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Sample records for additional delayed regional

  1. Network Delay Inference from Additive Metrics

    OpenAIRE

    Bhamidi, Shankar; Rajagopal, Ram; Roch, Sebastien

    2006-01-01

    We demonstrate the use of computational phylogenetic techniques to solve a central problem in inferential network monitoring. More precisely, we design a novel algorithm for multicast-based delay inference, i.e. the problem of reconstructing the topology and delay characteristics of a network from end-to-end delay measurements on network paths. Our inference algorithm is based on additive metric techniques widely used in phylogenetics. It runs in polynomial time and requires a sample of size ...

  2. Delayed imaging and additional methods to reduce subdiaphragmatic activity in myocardial perfusion SPECT imaging

    OpenAIRE

    Wosnitzer, Brian; Ata, Pashmina; DePuey, Ernest Gordon

    2015-01-01

    Compton scatter from radiotracer in structures close to the heart may partially or completely mask myocardial perfusion defects on SPECT imaging. Previous reports have discussed benefits of additional delayed imaging. We present a case in which additional delayed stress imaging reduced Compton scatter and unveiled clinically significant, stress-induced ischemia.

  3. Passivity and Passification of Memristor-Based Recurrent Neural Networks With Additive Time-Varying Delays.

    Science.gov (United States)

    Rakkiyappan, Rajan; Chandrasekar, Arunachalam; Cao, Jinde

    2015-09-01

    This paper presents a new design scheme for the passivity and passification of a class of memristor-based recurrent neural networks (MRNNs) with additive time-varying delays. The predictable assumptions on the boundedness and Lipschitz continuity of activation functions are formulated. The systems considered here are based on a different time-delay model suggested recently, which includes additive time-varying delay components in the state. The connection between the time-varying delay and its upper bound is considered when estimating the upper bound of the derivative of Lyapunov functional. It is recognized that the passivity condition can be expressed in a linear matrix inequality (LMI) format and by using characteristic function method. For state feedback passification, it is verified that it is apathetic to use immediate or delayed state feedback. By constructing a Lyapunov-Krasovskii functional and employing Jensen's inequality and reciprocal convex combination technique together with a tighter estimation of the upper bound of the cross-product terms derived from the derivatives of the Lyapunov functional, less conventional delay-dependent passivity criteria are established in terms of LMIs. Moreover, second-order reciprocally convex approach is employed for deriving the upper bound for terms with inverses of squared convex parameters. The model based on the memristor with additive time-varying delays widens the application scope for the design of neural networks. Finally, pertinent examples are given to show the advantages of the derived passivity criteria and the significant improvement of the theoretical approaches. PMID:25415991

  4. Formation of "delayed risks" in regional innovative production

    Directory of Open Access Journals (Sweden)

    Olga Avdeychik

    2014-02-01

    Full Text Available The article considers specific features of functioning of regional complexes within the framework of joint realization of both Sustainable Development Concept and an innovation strategy which provides a synergistic result of achieving optimal economic parameters while minimizing negative anthropogenic impact on the environment. Violation of the optimal equilibrium in the simultaneous implementation of both strategies increases the probability of manifestation of environmental and economic risks and economic risks, due to increasing share of waste at different stages of life cycle of industrial products with a predominant innovation component. Disproportions in the implementation of modern approaches to innovations functioning with regard to regional specifics of sustainable development increase adverse effects on the ecosystem. Forming a background of delayed technologic and environmental risk, they increase the likelihood of economic risk, reducing the effectiveness of already implemented innovations. An effective strategy for minimization of delayed risks to different species is the formation of regional cluster structures which include industrial, managerial, research and training components based on integration of intellectual, material and technological resources.

  5. Regional White Matter Volumes Correlate with Delay Discounting

    OpenAIRE

    Yu, Rongjun

    2012-01-01

    A preference for immediate gratification is a central feature in addictive processes. However, the neural structures underlying reward delay tolerance are still unclear. Healthy participants (n = 121) completed a delay discounting questionnaire assessing the extent to which they prefer smaller immediate rewards to larger delayed reward after undergoing magnetic resonance imaging (MRI) scanning. Whole brain voxel-based morphometric analysis shows that delay discounting severity was negatively ...

  6. Regional white matter volumes correlate with delay discounting.

    Directory of Open Access Journals (Sweden)

    Rongjun Yu

    Full Text Available A preference for immediate gratification is a central feature in addictive processes. However, the neural structures underlying reward delay tolerance are still unclear. Healthy participants (n = 121 completed a delay discounting questionnaire assessing the extent to which they prefer smaller immediate rewards to larger delayed reward after undergoing magnetic resonance imaging (MRI scanning. Whole brain voxel-based morphometric analysis shows that delay discounting severity was negatively correlated with right prefrontal subgyral white matter volume and positively correlated with white matter volume in parahippocampus/hippocampus, after whole brain correction. This study might better our understanding of the neural basis of impulsivity and addiction.

  7. Mixed butanols addition to gasoline surrogates: Shock tube ignition delay time measurements and chemical kinetic modeling

    KAUST Repository

    AlRamadan, Abdullah S.

    2015-10-01

    The demand for fuels with high anti-knock quality has historically been rising, and will continue to increase with the development of downsized and turbocharged spark-ignition engines. Butanol isomers, such as 2-butanol and tert-butanol, have high octane ratings (RON of 105 and 107, respectively), and thus mixed butanols (68.8% by volume of 2-butanol and 31.2% by volume of tert-butanol) can be added to the conventional petroleum-derived gasoline fuels to improve octane performance. In the present work, the effect of mixed butanols addition to gasoline surrogates has been investigated in a high-pressure shock tube facility. The ignition delay times of mixed butanols stoichiometric mixtures were measured at 20 and 40bar over a temperature range of 800-1200K. Next, 10vol% and 20vol% of mixed butanols (MB) were blended with two different toluene/n-heptane/iso-octane (TPRF) fuel blends having octane ratings of RON 90/MON 81.7 and RON 84.6/MON 79.3. These MB/TPRF mixtures were investigated in the shock tube conditions similar to those mentioned above. A chemical kinetic model was developed to simulate the low- and high-temperature oxidation of mixed butanols and MB/TPRF blends. The proposed model is in good agreement with the experimental data with some deviations at low temperatures. The effect of mixed butanols addition to TPRFs is marginal when examining the ignition delay times at high temperatures. However, when extended to lower temperatures (T < 850K), the model shows that the mixed butanols addition to TPRFs causes the ignition delay times to increase and hence behaves like an octane booster at engine-like conditions. © 2015 The Combustion Institute.

  8. Fokker-Planck description for a linear delayed Langevin equation with additive Gaussian noise

    Science.gov (United States)

    Giuggioli, Luca; McKetterick, Thomas John; Kenkre, V. M.; Chase, Matthew

    2016-09-01

    We construct an equivalent probability description of linear multi-delay Langevin equations subject to additive Gaussian white noise. By exploiting the time-convolutionless transform and a time variable transformation we are able to write a Fokker-Planck equation (FPE) for the 1-time and for the 2-time probability distributions valid irrespective of the regime of stability of the Langevin equations. We solve exactly the derived FPEs and analyze the aging dynamics by studying analytically the conditional probability distribution. We discuss explicitly why the initially conditioned distribution is not sufficient to describe fully out a non-Markov process as both preparation and observation times have bearing on its dynamics. As our analytic procedure can also be applied to linear Langevin equations with memory kernels, we compare the non-Markov dynamics of a one-delay system with that of a generalized Langevin equation with an exponential as well as a power law memory. Application to a generalization of the Green-Kubo formula is also presented.

  9. Identification and systematical studies of the electron-capture delayed fission (ECDF) in the lead region

    CERN Multimedia

    Pauwels, D B; Lane, J

    2008-01-01

    In our recent experiment (March 2007) at the velocity filter SHIP(GSI) we observed the electron-capture delayed fission of the odd-odd isotope $^{194}$At. This is the first unambiguous identification of this phenomenon in the very neutron-deficient nuclei in the vicinity of the proton shell closure at Z=82. In addition, the total kinetic energy (TKE) for the daughter nuclide $^{194}$Po was measured, despite the fact that this isotope does not decay via spontaneous fission. Semi-empirical analysis of the electron-capture Q$_{EC}$ values and fission barriers B$_{f}$ shows that a relatively broad island of ECDF must exist in this region of the Nuclide Chart, with some of the nuclei having unusually high ECDF probabilities. Therefore, this Proposal is intended to initiate the systematic identification and study of $\\beta$-delayed fission at ISOLDE in the very neutron-deficient lead region. Our aim is to provide unique low-energy fission data (e.g. probabilities, TKE release, fission barriers and their isospin dep...

  10. Bifurcation behaviors of synchronized regions in logistic map networks with coupling delay

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Longkun, E-mail: tomlk@hqu.edu.cn, E-mail: xqwu@whu.edu.cn [School of Mathematical Science, Huaqiao University, Quanzhou 362021 (China); Wu, Xiaoqun, E-mail: tomlk@hqu.edu.cn, E-mail: xqwu@whu.edu.cn; Lu, Jun-an, E-mail: jalu@whu.edu.cn [School of Mathematics and Statistics, Wuhan University, Wuhan 430072 (China); Lü, Jinhu, E-mail: jhlu@iss.ac.cn [LSC, Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190 (China); Faculty of Engineering, King Abdulaziz University, Jeddah (Saudi Arabia)

    2015-03-15

    Network synchronized regions play an extremely important role in network synchronization according to the master stability function framework. This paper focuses on network synchronous state stability via studying the effects of nodal dynamics, coupling delay, and coupling way on synchronized regions in Logistic map networks. Theoretical and numerical investigations show that (1) network synchronization is closely associated with its nodal dynamics. Particularly, the synchronized region bifurcation points through which the synchronized region switches from one type to another are in good agreement with those of the uncoupled node system, and chaotic nodal dynamics can greatly impede network synchronization. (2) The coupling delay generally impairs the synchronizability of Logistic map networks, which is also dominated by the parity of delay for some nodal parameters. (3) A simple nonlinear coupling facilitates network synchronization more than the linear one does. The results found in this paper will help to intensify our understanding for the synchronous state stability in discrete-time networks with coupling delay.

  11. An LMI Approach to H∞ Performance Analysis of Continous-Time System with Two Additive Time-Varying Delays

    Directory of Open Access Journals (Sweden)

    Wrastawa Ridwan

    2011-08-01

    Full Text Available This paper investigates the problem of H∞ performance analysis for continous–time systems with two additive time-varying delays in the state. Our objective is focused on stability analysis of a continuous system with two time-varying delays with an H∞ disturbance attenuation level γ. By exploiting Lyapunov-Krasovski functional and introducing free weighting matrix variables, LMI stability condition have been derived.

  12. Delayed Adrenarche may be an Additional Feature of Immunoglobulin Super Family Member 1 Deficiency Syndrome.

    Science.gov (United States)

    Hulle, Severine Van; Craen, Margarita; Callewaert, Bert; Joustra, Sjoerd; Oostdijk, Wilma; Losekoot, Monique; Wit, Jan Maarten; Turgeon, Marc Olivier; Bernard, Daniel J; Schepper, Jean De

    2016-03-01

    Immunoglobulin super family member 1 (IGSF1) deficiency syndrome is characterized by central hypothyroidism, delayed surge in testosterone during puberty, macro-orchidism, and in some cases, hypoprolactinemia and/or transient growth hormone (GH) deficiency. Our patient was a 19-year-old male adolescent who had been treated since the age of 9 years with GH and thyroxine for an idiopathic combined GH, thyroid-stimulating hormone (TSH), and prolactin (PRL) deficiency. His GH deficiency proved to be transient, but deficiencies of TSH and PRL persisted, and he had developed macro-orchidism since the end of puberty. Brain magnetic resonance imaging and PROP1 and POU1F1 sequencing were normal. A disharmonious puberty (delayed genital and pubic hair development, bone maturation, and pubertal growth spurt, despite normal testicular growth) was observed as well as a delayed adrenarche, as reflected by very low dehydroepiandrosterone sulfate and delayed pubarche. Direct sequencing of the IGSF1 gene revealed a novel hemizygous mutation, c.3127T>C, p.Cys1043Arg. Pathogenicity of the mutation was demonstrated in vitro. Male children with an idiopathic combined GH, PRL, and TSH deficiency, showing persistent central hypothyroidism but transient GH deficiency upon retesting at adult height, should be screened for mutations in the IGSF1 gene, especially when macro-orchidism and/or hypoprolactinemia are present. We suspect that delayed adrenarche, as a consequence of PRL deficiency, might be part of the clinical phenotype of patients with IGSF1 deficiency. PMID:26757742

  13. Stability Region Analysis of PID and Series Leading Correction PID Controllers for the Time Delay Systems

    Directory of Open Access Journals (Sweden)

    D. RAMA REDDY

    2012-07-01

    Full Text Available This paper describes the stability regions of PID (Proportional +Integral+ Derivative and a new PID with series leading correction (SLC for Networked control system with time delay. The new PID controller has a tuning parameter ‘β’. The relation between β, KP, KI and KD is derived. The effect of plant parameters on stabilityregion of PID controllers and SLC-PID controllers in first-order and second-order systems with time delay are also studied. Finally, an open-loop zero was inserted into the plant-unstable second order system with time delay so that the stability regions of PID and SLC-PID controllers get effectively enlarged. The total system isimplemented using MATLAB/Simulink.

  14. Delayed onset of tricuspid valve flow in repaired tetralogy of Fallot: an additional mechanism of diastolic dysfunction and interventricular dyssynchrony

    Directory of Open Access Journals (Sweden)

    Benson Lee N

    2011-08-01

    Full Text Available Abstract Background Diastolic dysfunction of the right ventricle (RV is common after repair of tetralogy of Fallot. While restrictive physiology in late diastole has been well known, dysfunction in early diastole has not been described. The present study sought to assess the prevalence and mechanism of early diastolic dysfunction of the RV defined as delayed onset of the tricuspid valve (TV flow after TOF repair. Methods The study population consisted of 31 children with repaired TOF (mean age ± SD, 12.3 ± 4.1 years who underwent postoperative cardiovascular magnetic resonance (CMR. The CMR protocol included simultaneous phase-contrast velocity mapping of the atrioventricular valves, which enabled direct comparison of the timing and patterns of tricuspid (TV and mitral (MV valve flow. The TV flow was defined to have delayed onset when its onset was > 20 ms later than the onset of the MV flow. The TV and MV flow from 14 normal children was used for comparison. The CMR results were correlated with the findings on echocardiography and electrocardiography. Result Delayed onset of the TV flow was observed in 16/31 patients and in none of the controls. The mean delay time was 64.81 ± 27.07 ms (8.7 ± 3.2% of R-R interval. The delay time correlated with the differences in duration of the TV and MV flow (55.94 ± 32.88 ms (r = 0.90, p Conclusions Early diastolic dysfunction with delayed onset of TV flow is common after TOF repair, and is associated with reduced RV ejection fraction. It is a further manifestation of interventricular dyssynchrony and represent an additional mechanism of ventricular diastolic dysfunction.

  15. Achievable Rate Regions for the Causal Cognitive Interference Channel With Delay

    CERN Document Server

    Mirmohseni, Mahtab; Aref, Mohammad Reza

    2010-01-01

    In this paper, we introduce the Causal Cognitive Interference Channel With Delay (CC-IFC-WD) in which the cognitive user transmission can depend on the L future received symbols as well as the past ones. Taking the effect of the link delays into account, CC-IFC-WD fills the gap between the genie-aided and causal cognitive radio channels. We study three special cases: 1)Classical CC-IFC (L=0), 2)CC-IFC without delay (L=1) and 3)CC-IFC with a block length delay (L=n). In each situation, we obtain an inner bound on the capacity region. Our coding schemes make use of cooperative strategy by generalized block Markov superposition coding, collaborative strategy by rate splitting, and Gel'fand-Pinsker coding in order to pre-cancel part of the interference. Moreover, instantaneous relaying and non-causal partial Decode-and-Forward are employed in the second and third cases, respectively. The derived achievable rate regions under special conditions, reduce to several previously known ones.

  16. Calibration of regional ionospheric delay with uncombined precise point positioning and accuracy assessment

    Indian Academy of Sciences (India)

    Li Wei; Cheng Pengfei; Bei Jinzhong; Wen Hanjiang; Wang Hua

    2012-08-01

    A new method for the calibration of regional ionospheric delay based on uncombined precise point positioning (U-PPP) is proposed in this study. The performance of the new method was comparatively validated in terms of its accuracy and robustness with respect to the phase-smoothed pseudorange (PSP) method through two short-baseline experiments. Accuracy of the PPP-derived ionospheric delays was further assessed by interpolating them to a user station to perform single-frequency simulated kinematic PPP. Two 24-hr period datasets of four continuous operation reference system (CORS) stations were analyzed, collected during calm and disturbed ionospheric conditions, respectively. The single-frequency GPS observables from a user station, that were a-priori corrected by the interpolated ionospheric delays, were utilized to implement single-frequency PPP (SF-PPP). The results show that interpolation accuracy is better than 1 dm and, with the proposed method, is less affected by the ionospheric activity; meanwhile, positioning accuracy of SF-PPP was 4 ∼5 cm (horizontal) and better than 1 dm (vertical). For comparison, two reference SF-PPP solutions were also obtained, in which the ionospheric delays are eliminated either by forming semi-combination observations or by using global ionosphere maps (GIM) model values; in both cases the positioning accuracy was only 4 ∼7 dm (horizontal) and 1 m (vertical). These results provide a further demonstration of the performance of PPP-based regional ionospheric calibration in the parameter domain.

  17. Effects of delayed treatment with nebracetam on neurotransmitters in brain regions after microsphere embolism in rats

    OpenAIRE

    Takeo, Satoshi; Hayashi, Hideki; Miyake, Keiko; Takagi, Kaori; Tadokoro, Mina; Takagi, Norio; Oshikawa, Sayuri

    1997-01-01

    The effects of delayed treatment with nebracetam, a novel nootropic drug, on neurotransmitters of brain regions were examined in rats with microsphere embolism-induced cerebral ischaemia.Cerebral ischaemia was induced by administration of 900 microspheres (48 μm) into the internal carotid artery. The rats with stroke-like symptoms were treated p.o. with 30 mg kg−1 nebracetam twice daily. The levels of acetylcholine, dopamine, noradrenaline, 5-hydroxytryptamine (5-HT) and their metabolites in ...

  18. Delayed Proton Emission in the A=70 Region, a Strobe for Level Density and Particle Width

    CERN Multimedia

    2002-01-01

    The delayed particle emission, which is a characteristic signature of the most exotic nuclei decay, provides a wide variety of spectroscopic information among which level density, and gives in some cases access to selected microscopic structures. In regard to these two aspects the $\\beta^+$-EC delayed proton emission in the A=70 neutron deficient mass region is of special interest to be investigated. Indeed, in this area located close to the proton drip line and along the N=Z line, the delayed proton emission constitutes an access to level density in the Q$_{EC}$-S$_p$ window of the emitting nucleus. Moreover, the unbound states populated by the EC process are expected to exhibit lifetimes in the vicinity of the K electronic shell filling time ($\\tau\\!\\sim\\!2\\times10^{-16}$s) and so the particle widths can be reached via proton X-ray coincidence measurements (PXCT). From theoretical approaches strongly deformed low-spin proton unbound levels which may be populated in the T$_Z$ = 1/2 precursors decay are predi...

  19. Increased risk of schizophrenia from additive interaction between infant motor developmental delay and obstetric complications: evidence from a population-based longitudinal study.

    LENUS (Irish Health Repository)

    Clarke, Mary C

    2011-12-01

    Obstetric complications and developmental delay are well-established risk factors for schizophrenia. The authors investigated whether these risk factors interact in an additive manner to further increase risk for schizophrenia.

  20. Stability regions for synchronized τ-periodic orbits of coupled maps with coupling delay τ

    Science.gov (United States)

    Karabacak, Özkan; Alikoç, Baran; Atay, Fatihcan M.

    2016-09-01

    Motivated by the chaos suppression methods based on stabilizing an unstable periodic orbit, we study the stability of synchronized periodic orbits of coupled map systems when the period of the orbit is the same as the delay in the information transmission between coupled units. We show that the stability region of a synchronized periodic orbit is determined by the Floquet multiplier of the periodic orbit for the uncoupled map, the coupling constant, the smallest and the largest Laplacian eigenvalue of the adjacency matrix. We prove that the stabilization of an unstable τ-periodic orbit via coupling with delay τ is possible only when the Floquet multiplier of the orbit is negative and the connection structure is not bipartite. For a given coupling structure, it is possible to find the values of the coupling strength that stabilizes unstable periodic orbits. The most suitable connection topology for stabilization is found to be the all-to-all coupling. On the other hand, a negative coupling constant may lead to destabilization of τ-periodic orbits that are stable for the uncoupled map. We provide examples of coupled logistic maps demonstrating the stabilization and destabilization of synchronized τ-periodic orbits as well as chaos suppression via stabilization of a synchronized τ-periodic orbit.

  1. Reactive changes in astrocytes, and delayed neuronal death, in the rat hippocampal CA1 region following cerebral ischemia/reperfusion

    Institute of Scientific and Technical Information of China (English)

    Guiqing Zhang; Xiang Luo; Zhiyuan Yu; Chao Ma; Shabei Xu; Wei Wang

    2009-01-01

    BACKGROUND: Blood supply to the hippocampus is not provided by the middle cerebral artery. However, previous studies have shown that delayed neuronal death in the hippocampus may occur following focal cerebral ischemia induced by middle cerebral artery occlusion. OBJECTIVE: To observe the relationship between reactive changes in hippocampal astrocytes and delayed neuronal death in the hippocampal CA1 region following middle cerebral artery occlusion. DESIGN, TIME AND SETTING: The immunohistochemical, randomized, controlled animal study was performed at the Laboratory of Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, from July to November 2007. MATERIALS: Rabbit anti-glial fibrillary acidic protein (GFAP) (Neomarkers, USA), goat anti-rabbit IgG (Sigma, USA) and ApoAlert apoptosis detection kit (Biosciences Clontech, USA) were used in this study. METHODS: A total of 42 healthy adult male Wistar rats, aged 3-5 months, were randomly divided into a sham operation group (n = 6) and a cerebral ischemia/reperfusion group (n = 36). In the cerebral ischemia/reperfusion group, cerebral ischemia/reperfusion models were created by middle cerebral artery occlusion. In the sham operation group, the thread was only inserted into the initial region of the internal carotid artery, and middle cerebral artery occlusion was not induced. Rats in the cerebral ischemia/reperfusion group were assigned to a delayed neuronal death (+) subgroup and a delayed neuronal death (-) subgroup, according to the occurrence of delayed neuronal death in the ischemic side of the hippocampal CA1 region following cerebral ischemia. MAIN OUTCOME MEASURES: Delayed neuronal death in the hippocampal CA1 region was measured by Nissl staining. GFAP expression and delayed neuronal death changes were measured in the rat hippocampal CA1 region at the ischemic hemisphere by double staining for GFAP and TUNEL. RESULTS: After 3 days of ischemia

  2. $\\beta$-delayed fission in proton-rich nuclei in the lead region

    CERN Document Server

    AUTHOR|(CDS)2085005; Huyse, Mark; Popescu, Lucia

    Nuclear fission is the breakup of an atomic nucleus into two (sometimes three) fragments, thereby releasing a large amount of energy. Soon after its discovery in the late 1930’s, the gross properties of the fission phenomenon were explained by macroscopic nuclear models. Certain features however, such as asymmetric fission-fragment mass distributions in the actinide region, require the inclusion of microscopic effects. This interplay of the microscopic motion of individual nucleons on this macroscopic process is, until today, not yet fully understood. The phenomenon of fission has therefore been of recurring interest for both theoretical and experimental studies. This thesis work focuses on the $\\beta$-delayed fission ($\\beta$DF) process, an excellent tool to study low-energy fission of exotic nuclei, which was discovered in 1966 in the actinide region. In this two-step process, a precursor nucleus first undergoes $\\beta$-decay to an excited level in the daughter nucleus, which may subsequently fission. Rec...

  3. Combined action of time-delay and colored cross-associated multiplicative and additive noises on stability and stochastic resonance for a stochastic metapopulation system

    Science.gov (United States)

    Wang, Kang-Kang; Zong, De-Cai; Wang, Ya-Jun; Li, Sheng-Hong

    2016-05-01

    In this paper, the transition between the stable state of a big density and the extinction state and stochastic resonance (SR) for a time-delayed metapopulation system disturbed by colored cross-correlated noises are investigated. By applying the fast descent method, the small time-delay approximation and McNamara and Wiesenfeld's SR theory, we investigate the impacts of time-delay, the multiplicative, additive noises and colored cross-correlated noise on the SNR and the shift between the two states of the system. Numerical results show that the multiplicative, additive noises and time-delay can all speed up the transition from the stable state to the extinction state, while the correlation noise and its correlation time can slow down the extinction process of the population system. With respect to SNR, the multiplicative noise always weakens the SR effect, while noise correlation time plays a dual role in motivating the SR phenomenon. Meanwhile, time-delay mainly plays a negative role in stimulating the SR phenomenon. Conversely, it could motivate the SR effect to increase the strength of the cross-correlation noise in the SNR-β plot, while the increase of additive noise intensity will firstly excite SR, and then suppress the SR effect.

  4. Vascular Steal Explains Early Paradoxical Blood Oxygen Level-Dependent Cerebrovascular Response in Brain Regions with Delayed Arterial Transit Times

    Directory of Open Access Journals (Sweden)

    Julien Poublanc

    2013-04-01

    Full Text Available Introduction: Blood oxygen level-dependent (BOLD magnetic resonance imaging (MRI during manipulation of inhaled carbon dioxide (CO2 can be used to measure cerebrovascular reactivity (CVR and map regions of exhausted cerebrovascular reserve. These regions exhibit a reduced or negative BOLD response to inhaled CO2. In this study, we sought to clarify the mechanism behind the negative BOLD response by investigating its time delay (TD. Dynamic susceptibility contrast (DSC MRI with the injection of a contrast agent was used as the gold standard in order to provide measurement of the blood arrival time to which CVR TD could be compared. We hypothesize that if negative BOLD responses are the result of a steal phenomenon, they should be synchronized with positive BOLD responses from healthy brain tissue, even though the blood arrival time would be delayed. Methods: On a 3-tesla MRI system, BOLD CVR and DSC images were collected in a group of 19 patients with steno-occlusive cerebrovascular disease. For each patient, we generated a CVR magnitude map by regressing the BOLD signal with the end-tidal partial pressure of CO2 (PETCO2, and a CVR TD map by extracting the time of maximum cross-correlation between the BOLD signal and PETCO2. In addition, a blood arrival time map was generated by fitting the DSC signal with a gamma variate function. ROI masks corresponding to varying degrees of reactivity were constructed. Within these masks, the mean CVR magnitude, CVR TD and DSC blood arrival time were extracted and averaged over the 19 patients. CVR magnitude and CVR TD were then plotted against DSC blood arrival time. Results: The results show that CVR magnitude is highly correlated to DSC blood arrival time. As expected, the most compromised tissues with the longest blood arrival time have the lowest (most negative CVR magnitude. However, CVR TD shows a noncontinuous relationship with DSC blood arrival time. CVR TD is well correlated to DSC blood arrival time

  5. Factors influencing surgical delay after hip fracture in hospitals of Emilia Romagna Region, Italy: a multilevel analysis.

    Science.gov (United States)

    Belotti, Laura Maria Beatrice; Bartoli, Simona; Trombetti, Susanna; Montella, Maria Teresa; Toni, Aldo; De Palma, Rossana

    2013-01-01

    Hip fracture is becoming a major public health concern, with associated mortality and morbidity particularly in the elderly. This study aims to investigate factors (i.e. patient factors and hospital variables) associated with increased risk for delaying surgery after hip fractures, and to assess whether and to what extent timing was associated with mortality risk. All patients aged 65 and over, resident in Emilia Romagna Region (Italy) and admitted to hospital for hip fracture (2009 - 2010) were selected. Data on surgical delay were adjusted using multilevel logistic regression model. A Cox proportional hazard model was fitted to a propensity score matched sample to assess mortality between delayed and early treated patients. Of the 10, 995 patients included (mean age: 83.3 years), 44.9% underwent surgery within 2 days. Significant risk factors for delayed surgery were: gender (OR: 1.16), comorbidity (OR: 1.29), anticoagulant (OR: 7.64) ,antiplatelet medication (OR: 2.43) , type of procedure (OR: 1.37) and day of admission (OR: Thu-Fri: 6.05; Sat-Sun: 1.17). Type of hospital and annual volume of hip fracture surgeries were not sufficient to explain hospital variability. A significant difference in mortality rate between early and delayed surgery emerged six months post surgery. PMID:23397198

  6. Pubertal hormones modulate the addition of new cells to sexually dimorphic brain regions

    OpenAIRE

    Ahmed, Eman I.; Zehr, Julia L.; Schulz, Kalynn M.; Lorenz, Betty H.; Doncarlos, Lydia L.; Sisk, Cheryl L.

    2008-01-01

    New cells, including neurons, arise in several brain regions during puberty in rats. Sex differences in pubertal addition of cells coincide with adult sexual dimorphisms: for each region, the sex that gains more cells during puberty has a larger volume in adulthood. Removing gonadal hormones before puberty eliminates these sex differences, indicating that gonadal steroids direct the addition of new cells during puberty to maintain and accentuate sexual dimorphisms in the adult brain.

  7. The Structure of the Broad Line Region in AGN: I. Reconstructed Velocity-Delay Maps

    CERN Document Server

    Grier, C J; Horne, Keith; Bentz, M C; Pogge, R W; Denney, K D; De Rosa, G; Martini, Paul; Kochanek, C S; Zu, Y; Shappee, B; Siverd, R; Beatty, T G; Sergeev, S G; Kaspi, S; Salvo, C Araya; Bird, J C; Bord, D J; Borman, G A; Che, X; Chen, C; Cohen, S A; Dietrich, M; Doroshenko, V T; Efimov, Yu S; Free, N; Ginsburg, I; Henderson, C B; King, A L; Mogren, K; Molina, M; Mosquera, A M; Nazarov, S V; Okhmat, D N; Pejcha, O; Rafter, S; Shields, J C; Skowron, J; Szczygiel, D M; Valluri, M; van Saders, J L

    2012-01-01

    We present velocity-resolved reverberation results for five active galactic nuclei. We recovered velocity-delay maps using the maximum-entropy method for four objects: Mrk 335, Mrk 1501, 3C120, and PG2130+099. For the fifth, Mrk 6, we were only able to measure mean time delays in different velocity bins of the H\\beta\\ emission line, but see tentative evidence of combined virial motion and infalling gas. The four velocity-delay maps show unique dynamical signatures for each object. For 3C120, the Balmer lines show kinematic signatures consistent with both an inclined disk and infalling gas, but the HeII 4686 emission line is suggestive only of inflow. The Balmer lines in Mrk 335, Mrk 1501, and PG 2130+099 show signs of infalling gas, but the HeII emission in Mrk 335 is consistent with an inclined disk. The maps for 3C120 and Mrk 335 are two of the most clearly defined velocity-delay maps to date. These maps constitute a large increase in the number of objects for which we have resolved velocity-delay maps and ...

  8. Addition of ketamine or dexmedetomidine to lignocaine in intravenous regional anesthesia: A randomized controlled study

    Directory of Open Access Journals (Sweden)

    Alok Kumar

    2012-01-01

    Results: Shortened sensory and motor block onset times (69.17 min and 7.83 min respectively, P < 0.0001 and improved quality of anesthesia (satisfaction score = 3, P < 0.05 were found in ketamine group. Visual analog scale scores (3.21 ± 0.41 were comparable while time to first analgesic requirement (166.25 ± 25.89 min, P < 0.0001 was significantly longer in dexmedetomidine group after tourniquet release. Conclusion: We conclude that the addition of 1 mcg/kg of body weight dexmedetomidine or 0.5 mg/kg of body weight ketamine to lignocaine for IVRA improves quality of anesthesia and perioperative analgesia without causing side effects. We considered ketamine reduced the time for onset of block, delayed the onset of tourniquet pain, and reduced postoperative analgesic requirement and had a better patient satisfaction than placebo or dexmedetomidine.

  9. Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease

    NARCIS (Netherlands)

    Gutierrez-Achury, Javier; Zhernakova, Alexandra; Pulit, Sara L.; Trynka, Gosia; Hunt, Karen A.; Romanos, Jihane; Raychaudhuri, Soumya; van Heel, David A.; Wijmenga, Cisca; de Balcker, Paul I. W.

    2015-01-01

    Although dietary gluten is the trigger for celiac disease, risk is strongly influenced by genetic variation in the major histocompatibility complex (MHC) region. We fine mapped the MHC association signal to identify additional risk factors independent of the HLA-DQA1 and HLA-DQB1 alleles and observe

  10. Organic Matter and Water Addition Enhance Soil Respiration in an Arid Region

    OpenAIRE

    Liming Lai; Jianjian Wang; Yuan Tian; Xuechun Zhao; Lianhe Jiang; Xi Chen; Yong Gao; Shaoming Wang; Yuanrun Zheng

    2013-01-01

    Climate change is generally predicted to increase net primary production, which could lead to additional C input to soil. In arid central Asia, precipitation has increased and is predicted to increase further. To assess the combined effects of these changes on soil CO2 efflux in arid land, a two factorial manipulation experiment in the shrubland of an arid region in northwest China was conducted. The experiment used a nested design with fresh organic matter and water as the two controlled par...

  11. Proteasome alteration and delayed neuronal death in hippocampal CA1 and dentate gyrus regions following transient cerebral ischemia

    Institute of Scientific and Technical Information of China (English)

    Pengfei Ge; Tianfei Luo; Jizhou Zhang; Haifeng Wang; Wenchen Li; Yongxin Luan; Feng Ling; Yi'nan Luo

    2009-01-01

    BACKGROUND:Proteasome dysfunction has been reported to induce abnormal protein aggregation and cell death.OBJECTIVE:To investigate the effect of proteasome changes on delayed neuronal death in CA1 and dentate gyrus (DG) regions of the rat hippocampus following transient cerebral ischemia.DESIGN,TIME AND SETTING:A randomized,controlled animal experiment.The study was performed at the Department of Biochemistry and Molecular Biology,Norman Bethune Medical College of Jilin University,from September 2006 to May 2008.MATERIALS:Rabbit anti-19S S10B polyclonal antibody was purchased from Bioreagents,USA;propidium iodide and fluorescently-labeled goat anti-rabbit IgG were purchased from Jackson Immunoresearch,USA;hematoxylin and eosin staining solution was purchased from Sigma,USA;LSM 510 confocal microscope was purchased from Zeiss,Germany.METHODS:A total of 40 healthy Wistar rats,male,4 months old,were randomly divided into sham surgery group (n=8) and model group (n=32).Ischemic models were established in the model group by transient clamping of the bilateral carotid arteries and decreased blood pressure.After 20 minutes of global ischemia,the clamp was removed to allow blood flow for 30 minutes,4,24,and 72 hours,respectively,with 8 rats at each time point.The bilateral carotid arteries were not ligated in the sham surgery group.MAIN OUTCOME MEASURES:Neuronal death in the CA1 and DG regions was observed by hematoxylin-eosin staining.Proteasome expression in CA1 and DG region neurons was detected by immunohistochemistry.RESULTS:Hematoxylin-eosin staining showed neuronal death in the CA1 region alone at 72 hours of reperfusion following ischemia.In comparison to the sham surgery group,a significant decrease in proteasome expression was observed,by immunohistochemistry,in the CA1 and DG regions in the model group,following 30 minutes,4,24,and 72 hours of reperfusion (P<0.01).After 72 hours of reperfusion following ischemia,proteasome expression had almost completely

  12. Frequency, delay and velocity analysis for intrinsic channel region of carbon nanotube field effect transistors

    Directory of Open Access Journals (Sweden)

    P. Geetha

    2014-03-01

    Full Text Available Gate wrap around field effect transistor is preferred for its good channel control. To study the high frequency behaviour of the device, parameters like cut-off frequency, transit or delay time, velocity are calculated and plotted. Double-walled and array of channels are considered in this work for enhanced output and impedance matching of the device with the measuring equipment terminal respectively. The perfomance of double-walledcarbon nanotube is compared with single-walled carbon nanotube and found that the device with double-wall shows appreciable improvement in its characteristics. Analysis of these parameters are done with various values of source/drain length, gate length, tube diameters and channel densities. The maximum cut-off frequency is found to be 72.3 THz with corresponding velocity as 5x106 m/s for channel density as 3 and gate length as 11nm. The number of channel is varied from 3 to 21 and found that the perfromance of the device containing double-walled carbon nano tube is better for channel number lesser than or equal to 12. The proposed modelling can be used for designing devices to handle high speed applications of future generation.

  13. Organic matter and water addition enhance soil respiration in an arid region.

    Directory of Open Access Journals (Sweden)

    Liming Lai

    Full Text Available Climate change is generally predicted to increase net primary production, which could lead to additional C input to soil. In arid central Asia, precipitation has increased and is predicted to increase further. To assess the combined effects of these changes on soil CO2 efflux in arid land, a two factorial manipulation experiment in the shrubland of an arid region in northwest China was conducted. The experiment used a nested design with fresh organic matter and water as the two controlled parameters. It was found that both fresh organic matter and water enhanced soil respiration, and there was a synergistic effect of these two treatments on soil respiration increase. Water addition not only enhanced soil C emission, but also regulated soil C sequestration by fresh organic matter addition. The results indicated that the soil CO2 flux of the shrubland is likely to increase with climate change, and precipitation played a dominant role in regulating soil C balance in the shrubland of an arid region.

  14. Constraints on the broad line region from regularized linear inversion: Velocity-delay maps for five nearby active galactic nuclei

    CERN Document Server

    Skielboe, Andreas; Treu, Tommaso; Park, Daeseong; Barth, Aaron J; Bentz, Misty C

    2015-01-01

    Reverberation mapping probes the structure of the broad emission-line region (BLR) in active galactic nuclei (AGN). The radius of the BLR along with the virial velocity of the BLR gas can be used to measure the mass of the supermassive black hole. The main systematic uncertainty affecting reverberation mapping is the unknown structure of the BLR. We develop a new method for analysing reverberation mapping data based on regularized linear inversion (RLI) that includes statistical modelling of the AGN continuum light curves. This method enables fast, flexible, and robust calculation of velocity-resolved response maps to probe BLR structure. Contrary to other methods, RLI allows for negative response in the BLR, such as when some areas of the BLR respond in inverse proportion to a change in ionizing continuum luminosity. We present time delays, integrated response functions, and velocity-delay maps for the H{\\beta} broad emission line in five nearby AGN, as well as H{\\alpha} and H{\\gamma} broad emission lines in...

  15. Transferability of regional permafrost disturbance susceptibility modelling using generalized linear and generalized additive models

    Science.gov (United States)

    Rudy, Ashley C. A.; Lamoureux, Scott F.; Treitz, Paul; van Ewijk, Karin Y.

    2016-07-01

    To effectively assess and mitigate risk of permafrost disturbance, disturbance-prone areas can be predicted through the application of susceptibility models. In this study we developed regional susceptibility models for permafrost disturbances using a field disturbance inventory to test the transferability of the model to a broader region in the Canadian High Arctic. Resulting maps of susceptibility were then used to explore the effect of terrain variables on the occurrence of disturbances within this region. To account for a large range of landscape characteristics, the model was calibrated using two locations: Sabine Peninsula, Melville Island, NU, and Fosheim Peninsula, Ellesmere Island, NU. Spatial patterns of disturbance were predicted with a generalized linear model (GLM) and generalized additive model (GAM), each calibrated using disturbed and randomized undisturbed locations from both locations and GIS-derived terrain predictor variables including slope, potential incoming solar radiation, wetness index, topographic position index, elevation, and distance to water. Each model was validated for the Sabine and Fosheim Peninsulas using independent data sets while the transferability of the model to an independent site was assessed at Cape Bounty, Melville Island, NU. The regional GLM and GAM validated well for both calibration sites (Sabine and Fosheim) with the area under the receiver operating curves (AUROC) > 0.79. Both models were applied directly to Cape Bounty without calibration and validated equally with AUROC's of 0.76; however, each model predicted disturbed and undisturbed samples differently. Additionally, the sensitivity of the transferred model was assessed using data sets with different sample sizes. Results indicated that models based on larger sample sizes transferred more consistently and captured the variability within the terrain attributes in the respective study areas. Terrain attributes associated with the initiation of disturbances were

  16. Delayed X-Ray Afterglows from Obscured Gamma-Ray Bursts in Star-Forming Regions

    OpenAIRE

    Meszaros, P.; Gruzinov, A.

    2000-01-01

    For Gamma-Ray Bursts occurring in dense star-forming regions, the X-ray afterglow behavior minutes to days after the trigger may be dominated by the small-angle scattering of the prompt X-ray emission off dust grains. We give a simple illustrative model for the X-ray light curves at different X-ray energies, and discuss possible implications. A bump followed by a steeper decay in soft X-rays is predicted for bursts which are heavily obscured in the optical.

  17. Delayed neutron and delayed photon characteristics from photofission of 232Th, 235,238U, and 237Np with endpoint Bremsstrahlung photons in the giant dipole resonance region

    Science.gov (United States)

    Doré, D.; Dighe, P. M.; Berthoumieux, E.; Laborie, J.-M.; Ledoux, X.; Macary, V.; Panebianco, S.; Ridikas, D.

    2009-10-01

    A renewed interest in photonuclear reactions was stimulated by applications as radioactive ion beam production, irradiation stations by high energy photons, shielding of electron accelerators, etc. Today, a particular attention is paid to the non-destructive characterization of waste barrels and the detection of nuclear materials, both based on photofission process and the associated delayed neutron (DN) and delayed photon (DP) emissions. The need of accurate and complete data for DN and DP yields and time characteristics of actinides was the motivation for an experimental campaign, started in 2004. In this paper, the experimental setup and the data analysis method will be presented and the modeling work will be described. Experimental results for DN and DP characteristics will be compared to calculations in the case of photofission of 232Th, 235,238U, and 237Np.

  18. Inner Mongolia Autonomous Region (IMAR) energy base: Additional final report and recommendations

    Energy Technology Data Exchange (ETDEWEB)

    Clark, Woodrow W. II.; Isherwood, William [Clark Strategic Partners, PO Box 17975, Beverly Hills, CA 90210 (United States)

    2010-03-15

    The ADB authors felt that an additional set of recommendations were needed to the final Report. Two reasons guided that decision: one was simply that the planned and budgeted final presentation of the Report was to be made in December 07 in Beijing to high level members of the Central Government. That meeting was cancelled. No reason was given but due to the upcoming Olympic Games in August 2008, perhaps discussion of the energy issues in China were too sensitive. But the other reason for the need to state additional recommendations was basically to help support the IMAR government in its direction for the future. The IMAR Government throughout the two years of research for this Report were extremely supportive and actively following the presentations and data. It was obvious that they felt that the Report or parts of it, for example, helping the next Five Year Plan for all of China define what sustainable development was and was not. However there were other elements that emerged including strong support for new alternative energy business development, education in this area, and strong resistance to the IMAR becoming a pipeline for natural gas coming from Russia to China. In short IMAR and China did not want to become another dependent region on Russian fossil fuels. These issues and recommendations are built upon the ADB Report but did not become apart of it. (author)

  19. Detection of postischemic regional left ventricular delayed outward wall motion or diastolic stunning after exercise-induced ischemia in patients with stable effort angina by using color kinesis.

    Science.gov (United States)

    Ishii, Katsuhisa; Miwa, Kunihisa; Sakurai, Takahiro; Kataoka, Kazuaki; Imai, Makoto; Kintaka, Aya; Aoyama, Takeshi; Kawanami, Masaki

    2008-04-01

    To determine whether postischemic diastolic stunning could be detected using color kinesis, we evaluated regional left ventricular (LV) diastolic wall motion in 36 patients with stable effort angina and a coronary stenosis (> or = 70% of luminal diameter), and in 30 control subjects. Regional LV filling fraction in the short-axis view during the first 30% of the LV filling time (color kinesis diastolic index) was determined before, 20 minutes, 1 hour, and 24 hours after the treadmill exercise test. In 33 of the 36 patients (92%), new regional LV delayed outward motion during early diastole (color kinesis diastolic index < or = 40%) was detected at 20 minutes after exercise. The regional LV delayed diastolic wall motion showed significant improvement but persisted 1 hour afterward in 20 of 36 patients (56%), and disappeared 24 hours after exercise. Detection of regional stunned myocardium with impaired diastolic function may be a useful tool for the diagnosis of coronary artery disease.

  20. The structure of the broad-line region in active galactic nuclei. I. Reconstructed velocity-delay maps

    DEFF Research Database (Denmark)

    Grier, C.J.; Peterson, B.M.; Pogge, R.W.;

    2013-01-01

    We present velocity-resolved reverberation results for five active galactic nuclei. We recovered velocity-delay maps using the maximum entropy method for four objects: Mrk 335, Mrk 1501, 3C 120, and PG 2130+099. For the fifth, Mrk 6, we were only able to measure mean time delays in different...

  1. Tomography with P, PP and pP delay-time data and the three-dimensional mantle structure below the Caribbean region

    NARCIS (Netherlands)

    van der Hilst, R.D.

    1990-01-01

    I address in this thesis two principal topics. Firstly, in chapters 2 and 3 I discuss improvements on the method of P delay-time tomography which were necessary to obtain reliable tomographic images of the mantle structure below the Caribbean region. These improvements include the reduction of refer

  2. Dynamics of cerebral tissue injury and perfusion after temporary hypoxia-ischemia in the rat - Evidence for region-specific sensitivity and delayed damage

    NARCIS (Netherlands)

    Dijkhuizen, RM; Knollema, S; van der Worp, H. Bart; Ter Horst, GJ; De Wildt, DJ; van der Sprenkel, JWB; Tulleken, KAF; Nicolay, K

    1998-01-01

    Background and Purpose-Selective regional sensitivity and delayed damage in cerebral ischemia provide opportunities for directed and late therapy for stroke. Our aim was to characterize the spatial and temporal profile of ischemia-induced changes in cerebral perfusion and tissue status, with the use

  3. Serotonin Transporter Promoter Region (5-HTTLPR) Polymorphism Is Not Associated With Paroxetine-Induced Ejaculation Delay in Dutch Men With Lifelong Premature Ejaculation

    NARCIS (Netherlands)

    Janssen, Paddy K C; Zwinderman, Aeilko H; Olivier, Berend; Waldinger, Marcel D

    2014-01-01

    PURPOSE: To investigate the association between the 5-HT-transporter-gene-linked promoter region (5-HTTLPR) polymorphism and 20-mg paroxetine-induced ejaculation delay in men with lifelong premature ejaculation (LPE). MATERIALS AND METHODS: This was a prospective study of 10 weeks of paroxetine trea

  4. Delayed Treatment with Sodium Hydrosulfide Improves Regional Blood Flow and Alleviates Cecal Ligation and Puncture (CLP)-Induced Septic Shock.

    Science.gov (United States)

    Ahmad, Akbar; Druzhyna, Nadiya; Szabo, Csaba

    2016-08-01

    Cecal ligation and puncture (CLP)-induced sepsis is a serious medical condition, caused by a severe systemic infection resulting in a systemic inflammatory response. Recent studies have suggested the therapeutic potential of donors of hydrogen sulfide (H2S), a novel endogenous gasotransmitter and biological mediator in various diseases. The aim of the present study was to assess the effect of H2S supplementation in sepsis, with special reference to its effect on the modulation of regional blood flow. We infused sodium hydrosulfide (NaHS), a compound that produces H2S in aqueous solution (1, 3, or 10 mg/kg/h, for 1 h at each dose level) in control rats or rats 24 h after CLP, and measured blood flow using fluorescent microspheres. In normal control animals, NaHS induced a characteristic redistribution of blood flow, and reduced cardiac, hepatic, and renal blood flow in a dose-dependent fashion. In contrast, in rats subjected to CLP, cardiac, hepatic, and renal blood flow was significantly reduced; infusion of NaHS (1 mg/kg/h and 3 mg/kg/h) significantly increased organ blood flow. In other words, the effect of H2S on regional blood flow is dependent on the status of the animals (i.e., a decrease in blood flow in normal controls, but an increase in blood flow in CLP). We have also evaluated the effect of delayed treatment with NaHS on organ dysfunction and the inflammatory response by treating the animals with NaHS (3 mg/kg) intraperitoneally (i.p.) at 24 h after the start of the CLP procedure; plasma levels of various cytokines and tissue indicators of inflammatory cell infiltration and oxidative stress were measured 6 h later. After 24 h of CLP, glomerular function was significantly impaired, as evidenced by markedly increased (over 4-fold over baseline) blood urea nitrogen and creatinine levels; this increase was also significantly reduced by treatment with NaHS. NaHS also attenuated the CLP-induced increases in malondialdehyde levels (an index of

  5. Delayed Treatment with Sodium Hydrosulfide Improves Regional Blood Flow and Alleviates Cecal Ligation and Puncture (CLP)-Induced Septic Shock.

    Science.gov (United States)

    Ahmad, Akbar; Druzhyna, Nadiya; Szabo, Csaba

    2016-08-01

    Cecal ligation and puncture (CLP)-induced sepsis is a serious medical condition, caused by a severe systemic infection resulting in a systemic inflammatory response. Recent studies have suggested the therapeutic potential of donors of hydrogen sulfide (H2S), a novel endogenous gasotransmitter and biological mediator in various diseases. The aim of the present study was to assess the effect of H2S supplementation in sepsis, with special reference to its effect on the modulation of regional blood flow. We infused sodium hydrosulfide (NaHS), a compound that produces H2S in aqueous solution (1, 3, or 10 mg/kg/h, for 1 h at each dose level) in control rats or rats 24 h after CLP, and measured blood flow using fluorescent microspheres. In normal control animals, NaHS induced a characteristic redistribution of blood flow, and reduced cardiac, hepatic, and renal blood flow in a dose-dependent fashion. In contrast, in rats subjected to CLP, cardiac, hepatic, and renal blood flow was significantly reduced; infusion of NaHS (1 mg/kg/h and 3 mg/kg/h) significantly increased organ blood flow. In other words, the effect of H2S on regional blood flow is dependent on the status of the animals (i.e., a decrease in blood flow in normal controls, but an increase in blood flow in CLP). We have also evaluated the effect of delayed treatment with NaHS on organ dysfunction and the inflammatory response by treating the animals with NaHS (3 mg/kg) intraperitoneally (i.p.) at 24 h after the start of the CLP procedure; plasma levels of various cytokines and tissue indicators of inflammatory cell infiltration and oxidative stress were measured 6 h later. After 24 h of CLP, glomerular function was significantly impaired, as evidenced by markedly increased (over 4-fold over baseline) blood urea nitrogen and creatinine levels; this increase was also significantly reduced by treatment with NaHS. NaHS also attenuated the CLP-induced increases in malondialdehyde levels (an index of

  6. Studies on the Regional Cerebral Blood Flow in Delayed Carbon Monoxide sequelae using 99mTc-HMPAO

    International Nuclear Information System (INIS)

    8 patients of delayed CO sequelae were evaluated using Brain CT and 99mTc-HMPAO SPECT. The results were as follows; 1) CT findings of delayed CO sequelae were bilateral low density lesion in globus pallidus (1 pt.), diffuse low density in white matter with bilateral low density in white matter (1 pt.), diffuse low density in white matter with bilateral low density in globus pallidus (1 pt.), diffuse low density in white matter with cortical atrophy (1 pt.), bilateral low density in globus pallidus and diffuse low density in white matter with cortical atrophy (1 pt.) and normal in 3 pts. 2) 99mTc-HMPAO Brain SPECT findings of delayed CO sequelae were decreased regiona1 cerebral blood flow (rCBF) in frontal (1 among 8 pts.), frontal and basal ganglia (3 among 8 pts.), and diffuse patch decreased rCBF pattern (4 among 8 pts.) 3) 99mTc-HMPAO Brain SPECT study was well correlated with neurologic symptoms and signs in delayed CO sequelae. Our results may suggest that reduced cerebral blood flow contributes to the development of delayed CO sequelae.

  7. Serotonin Transporter Promoter Region (5-HTTLPR) Polymorphism Is Not Associated With Paroxetine-Induced Ejaculation Delay in Dutch Men With Lifelong Premature Ejaculation

    OpenAIRE

    Paddy K C Janssen; Zwinderman, Aeilko H; Olivier, Berend; Waldinger, Marcel D.

    2014-01-01

    PURPOSE: To investigate the association between the 5-HT-transporter-gene-linked promoter region (5-HTTLPR) polymorphism and 20-mg paroxetine-induced ejaculation delay in men with lifelong premature ejaculation (LPE). MATERIALS AND METHODS: This was a prospective study of 10 weeks of paroxetine treatment in 54 men with LPE. Intravaginal ejaculation latency time (IELT) was measured by stopwatch. Controls consisted of 92 Caucasian men. All men with LPE were genotyped for the 5-HTTLPR polymorphi...

  8. Additional Support for Individuals with Intellectual Disabilities and Challenging Behaviors in Regions of Northwest Europe

    Science.gov (United States)

    Lunenborg, Carolien B.; Nakken, H.; van der Meulen, B. F.; Ruijssenaars, A. J. J. M.

    2011-01-01

    One in 10 individuals with intellectual disability (ID) exhibits behaviors that represent a significant challenge to the people who support them. Parents and staff (such as direct support professionals) often are challenged in trying to find a solution to overcome or reduce these behaviors. A form of additional professional support (i.e., external…

  9. An Analytical Delay Model

    Institute of Scientific and Technical Information of China (English)

    MIN Yinghua; LI Zhongcheng

    1999-01-01

    Delay consideration has been a majorissue in design and test of high performance digital circuits. Theassumption of input signal change occurring only when all internal nodesare stable restricts the increase of clock frequency. It is no longertrue for wave pipelining circuits. However, previous logical delaymodels are based on the assumption. In addition, the stable time of arobust delay test generally depends on the longest sensitizable pathdelay. Thus, a new delay model is desirable. This paper explores thenecessity first. Then, Boolean process to analytically describe thelogical and timing behavior of a digital circuit is reviewed. Theconcept of sensitization is redefined precisely in this paper. Based onthe new concept of sensitization, an analytical delay model isintroduced. As a result, many untestable delay faults under thelogical delay model can be tested if the output waveforms can be sampledat more time points. The longest sensitizable path length is computedfor circuit design and delay test.

  10. Retrieval of Wet-Tropospheric Path Delay over Coastal and Inland Water Regions using Wide-band Millimeter-Wave Radiometry

    Science.gov (United States)

    Bosch-Lluis, Xavier; Gilliam, Kyle L.; Reising, Steven C.; Tanner, Alan B.; Brown, Shannon T.; Kangaslahti, Pekka

    2013-04-01

    Currently, wet-tropospheric path delay measurements over inland water and coastal areas are extremely sparse. They are generally limited to twice-per-day radiosonde launches and a small number of ground-based GPS or radiometer path delay measurements, as well as radar measurements of phase delay to a small number of fixed targets on the ground. Knowledge of the wet-tropospheric path delay is necessary for next-generation high-resolution altimeters, such as the Surface Water and Ocean Topography (SWOT) mission, in formulation and planned for launch in 2020. SWOT has two major science objectives. First, the oceanographic objective is to characterize ocean mesoscale and sub-mesoscale circulation with horizontal resolution of 10 km and order of 1 cm height precision. Second, the hydrological objective is to provide global height measurements of inland surface water bodies with area of greater than 250 square meters and flow rate of rivers with width greater than 100 m. Wet-tropospheric path delay retrieval over coastal and inland-water areas is needed to achieve both of these objectives with sufficient height accuracy. In addition, information on total precipitable water vapor under nearly all weather conditions is needed to improve initialization of numerical weather prediction models. Currently, 18-34 GHz microwave radiometers provide wet-path delay corrections for the Jason series of nadir-viewing altimeters. However, these retrievals are limited to open ocean, and land incursion is unacceptable within 40 km of coastlines. The addition of millimeter-wave radiometers (70-170 GHz) is needed to address this problem by providing smaller surface footprint dimensions proportional to wavelength. In this work, we present a prototype algorithm to demonstrate the potential to retrieve wet-tropospheric path delay from brightness temperatures measured by millimeter-wave radiometers using the Brightness Temperature Deflection Ratio (BTDR) method. The BTDR algorithm retrieves wet

  11. The Revealed Competitiveness of Major Ports in the East Asian Region: An Additive Market Share Analysis

    Directory of Open Access Journals (Sweden)

    Tae Seung Kim

    2015-12-01

    Full Text Available In the single cargo market, the ordinary market share analysis method has been the representative tool for revealed competitiveness analysis. This paper develops and employs an applied market share index called the additive market share (AMS. Data are collected from 15 major container ports for the 1998-2013 period. In comparison to the results of an ordinary market share analysis, the highest AMS is observed for the Bohai Rim port cluster from 2008, not for the Yangtze River cluster or the Pearl River cluster. There are substitutable relationships between Yangtze River and non-Chinese ports and between Pearl River and Bohai Rim ports from 2001. Finally, there is an internal competition at Pearl River and Yangtze River ports, whereas Bohai Rim and non-Chinese ports show internally complementary relationships.

  12. Serotonin Transporter Promoter Region (5-HTTLPR) Polymorphism Is Not Associated With Paroxetine-Induced Ejaculation Delay in Dutch Men With Lifelong Premature Ejaculation

    Science.gov (United States)

    Janssen, Paddy K.C.; Zwinderman, Aeilko H.; Olivier, Berend

    2014-01-01

    Purpose To investigate the association between the 5-HT-transporter-gene-linked promoter region (5-HTTLPR) polymorphism and 20-mg paroxetine-induced ejaculation delay in men with lifelong premature ejaculation (LPE). Materials and Methods This was a prospective study of 10 weeks of paroxetine treatment in 54 men with LPE. Intravaginal ejaculation latency time (IELT) was measured by stopwatch. Controls consisted of 92 Caucasian men. All men with LPE were genotyped for the 5-HTTLPR polymorphism. Allele frequencies and genotypes of short (S) and long (L) variants of the polymorphism were compared between patients and controls. Associations between the LL, SL, and SS genotypes and fold increase of mean IELT were investigated. Results Of the 54 patients, 43 (79.6%) responded to 20-mg paroxetine treatment with an ejaculation delay, whereas 11 patients (20.4%) did not respond; 44%, 18%, and 18% of the patients showed a fold increase in mean IELT of 2-10, 10-20, and more than 20, respectively. Of the 54 men, 14 (25.9%) had the LL genotype, 29 (53.7%) had the SL genotype, and 11 (20.4%) had the SS genotype. In the 92 controls, the LL, SL, and SS genotypes were present in 27 (29.3%), 41 (44.6%), and 24 (26.1%), respectively. No statistically significant differences were found in 5-HTTLPR allelic variations or in 5-HTTLPR gene variations. In all men treated with 20 mg paroxetine, analysis of variance of the natural logarithm of fold increase in the IELT showed no statistically significant difference according to genotype (p=0.83). Conclusions The 5-HTTLPR polymorphism is not associated with daily 20-mg paroxetine treatment-induced ejaculation delay in men with LPE. PMID:24578810

  13. Isotope techniques in studies of paleontology environmental reconstruction (vegetation and climate) in the delayed quaternario of two Brazilian regions

    International Nuclear Information System (INIS)

    This paper presents an attempt to reconstruct vegetation and climate changes in the central region of the state of Sao Paulo (Jaguariuna) and west of the state of Mato Grosso (Pontes e Lacerda) during the last 12,000 years BP, based on δ13C values of soil organic matter (SOM), 14 C dating and botanical identification of buried charcoal in the soil profiles. Sampling site in Sao Paulo was located under natural vegetation ('cerradao'), along the slope of small hills and in the top of slope under the semi-deciduous forest in Mato Grosso. Charcoal was found predominantly between 150 and 50 cm depth, indicating a period of greater frequency of fires in these regions, between 6,000 and 3,000 years BP. More enriched values of δ13C of SOM (predominance of C4 plants) were observed from approximately 12,000 to 7,000 years BP in Jaguariuna, indicating drier climate when compared with nowadays conditions. The charcoal analyses indicated the predominance of cerrado species. In Pontes e Lacerda site, the δ13C profile suggests the presence of C3 vegetation (forest) during the last 10,000 years and the most of identified charcoal fragments indicated the presence of semi-deciduous forest as well as cerrado species. (author)

  14. Delay in Contests

    OpenAIRE

    Bester, Helmut; Konrad, Kai A.

    2003-01-01

    "Why is there delay in contests? In this paper we follow and extend the line of reasoning of Carl von Clausewitz to explain delay. For a given contest technology, delay may occur if there is an asymmetry between defense and attack, if the expected change in relative strengths is moderate, and if the additional cost of investment in future strength is low." (author's abstract) "In Konfliktsituationen findet der 'showdown' häufig mit einer Verzögerung statt. Das ist überraschend, weil sich m...

  15. The effect of growing regions, microbiological fertilizers and soil additives on productivity of buckwheat (Fagopyrum esculentum Moench

    Directory of Open Access Journals (Sweden)

    Dolijanović Željko K.

    2014-01-01

    Full Text Available This study was aimed at investigating the productivity of buckwheat taking into account growing regions, especially altitude, since this species does not have demanding soil requirements. The experiments were conducted during 2009 and 2010 in two localities: Valjevo (the village of Jasenica at 300 m altitude - 2009 and the village of Jovanja at 160 m altitude - 2010, and Nova Varos (the village of Radijevići at 1,065 m altitude. Soil of the experimental plots at both localities was characterized by acidic chemical reactions, with 3-5% of humus. In addition, the soil was rich in potassium, but poor in phosphorus. Within the objective test, with four replications, microbiological fertilizers Bactofil and Slavol were applied just before planting, alone or in combination with soil additives (hydrogel and zeolite. Half of each plot was fertilized foliarly, by the application of microbiological fertilizer Slavol using the concentrations of 50 ml per 10 liters of water. As compared with the control (no fertilizer application, in all variants of fertilization with a top dressing, increased grain yields were obtained. Significantly higher grain yields of buckwheat were obtained in the first locality, especially in the variant of fertilization with the combined use of Slavol and soil conditioner hydrogel. [Projekat Ministarstva nauke Republike Srbije, br. TR-31037

  16. Clustered chimera states in delay coupled oscillator systems

    OpenAIRE

    Sethia, Gautam C.; Sen, Abhijit; Atay, Fatihcan M

    2008-01-01

    We investigate "chimera" states in a ring of identical phase oscillators coupled in a time-delayed and spatially non-local fashion. We find novel "clustered chimera" states that have spatially distributed phase coherence separated by incoherence with adjacent coherent regions in anti-phase. The existence of such time-delay induced phase clustering is further supported through solutions of a generalized functional self-consistency equation of the mean field. Our results highlight an additional...

  17. Delayed discharge.

    Science.gov (United States)

    Allen, Daniel

    2016-07-01

    Essential facts Delays in discharging older peo ple from hospital cost the NHS £820 million a year, according to a report from the National Audit Office (NAO). Last year in acute hospitals, 1.15 million bed days were lost to delayed transfers of care, an increase of 31% since 2013. The NAO says rising demand for NHS services is compounded by reduced local authority spending on adult social care - down by 10% since 2009-10. PMID:27380673

  18. Additional stratifications in the equatorial F region at dawn and dusk during geomagnetic storms: Role of electrodynamics

    Science.gov (United States)

    Sreeja, V.; Balan, N.; Ravindran, Sudha; Pant, Tarun Kumar; Sridharan, R.; Bailey, G. J.

    2009-08-01

    The role of electrodynamics in producing additional stratifications in the equatorial F region (F 3 layer) at dawn and dusk during geomagnetic storms is discussed. Two cases of F 3 layer at dawn (0600-0730 LT on 5 October 2000 and 8 December 2000) and one case of F 3 layer at dusk (1600-1730 LT on 5 October 2000) are observed, for the first time, by the digital ionosonde at the equatorial station Trivandrum (8.5°N 77°E dip ˜ 0.5°N) in India. The unusual F 3 layers occurred during the geomagnetic storms and are associated with southward turning of interplanetary magnetic field B z , suggesting that eastward prompt penetration electric field could be the main cause of the F 3 layers. The dawn F 3 layer on 5 October is modeled using the Sheffield University Plasmasphere-Ionosphere Model by using the E × B drift estimated from the real height variation of the ionospheric peak during the morning period. The model qualitatively reproduces the dawn F 3 layer. While the existing F 2 layer rapidly drifts upward and forms the F 3 layer and topside ledge, a new layer forming at lower heights develops into the normal F 2 layer.

  19. Familiarity to a Feed Additive Modulates Its Effects on Brain Responses in Reward and Memory Regions in the Pig Model.

    Science.gov (United States)

    Val-Laillet, David; Meurice, Paul; Clouard, Caroline

    2016-01-01

    Brain responses to feed flavors with or without a feed additive (FA) were investigated in piglets familiarized or not with this FA. Sixteen piglets were allocated to 2 dietary treatments from weaning until d 37: the naive group (NAI) received a standard control feed and the familiarized group (FAM) received the same feed added with a FA mainly made of orange extracts. Animals were subjected to a feed transition at d 16 post-weaning, and to 2-choice feeding tests at d 16 and d 23. Production traits of the piglets were assessed up to d 28 post-weaning. From d 26 onwards, animals underwent 2 brain imaging sessions (positron emission tomography of 18FDG) under anesthesia to investigate the brain activity triggered by the exposure to the flavors of the feed with (FA) or without (C) the FA. Images were analyzed with SPM8 and a region of interest (ROI)-based small volume correction (p evaluation, cognition and reward, and included the prefrontal cortex, insular cortex, fusiform gyrus, limbic system and corpus striatum. The FAM animals showed a moderate preference for the novel post-transition FA feed compared to the C feed on d 16, i.e., day of the feed transition (67% of total feed intake). The presence or absence of the FA in the diet from weaning had no impact on body weight, average daily gain, and feed efficiency of the animals over the whole experimental period (p ≥ 0.10). Familiar feed flavors activated the prefrontal cortex. The amygdala, insular cortex, and prepyriform area were only activated in familiarized animals exposed to the FA feed flavor. The perception of FA feed flavor in the familiarized animals activated the dorsal striatum differently than the perception of the C feed flavor in naive animals. Our data demonstrated that the perception of FA in familiarized individuals induced different brain responses in regions involved in reward anticipation and/or perception processes than the familiar control feed flavor in naive animals. Chronic exposure to

  20. Demographic determinants of delayed divorce.

    Science.gov (United States)

    Chan, L Y; Heaton, T B

    1989-01-01

    This study identifies factors that predict delayed divorce in the US. The findings show that factors which influence marital stability in general also correlate with delayed divorce in the same direction. Wife's age at marriage, age of the youngest child, wife's religion, region of residence, and metropolitan residence have substantial effects of delayed divorce, but the effects of race, parental divorce, premarital pregnancy, and socioeconomic status are small.

  1. Delayed privatization

    OpenAIRE

    Bernardo Bortolotti; Paolo Pinotti

    2008-01-01

    This paper studies the timing of privatization in 21 major developed economies in the 1977-2002 period. Duration analysis shows that political fragmentation plays a significant role in explaining government's decision to privatize: privatization is delayed longer in democracies characterized by a larger number of parties and operating under proportional electoral rules, as predicted by war of attrition models of economic reform. Results are robust to various assumptions on the underlying stat...

  2. Four patients with speech delay, seizures and variable corpus callosum thickness sharing a 0.440 Mb deletion in region 1q44 containing the HNRPU gene

    NARCIS (Netherlands)

    Caliebe, Almuth; Kroes, Hester Y.; van der Smagt, Jasper J.; Martin-Subero, Jose I.; Toennies, Holger; van 't Slot, Ruben; Nievelstein, Rutger A. J.; Muhle, Hiltrud; Stephani, Ulrich; Alfke, Karsten; Stefanova, Irina; Hellenbroich, Yorck; Gillessen-Kaesbach, Gabriele; Hochstenbach, Ron; Siebert, Reiner; Poot, Martin

    2010-01-01

    Structural genome aberrations are frequently associated with highly variable congenital phenotypes involving mental retardation and developmental delay. Although some of these aberrations may result in recognizable phenotypes, a high degree of phenotypic variability often complicates a comprehensive

  3. Synchronizing time delay systems using variable delay in coupling

    Energy Technology Data Exchange (ETDEWEB)

    Ambika, G., E-mail: g.ambika@iiserpune.ac.in [Indian Institute of Science Education and Research, Pune 411 021 (India); Amritkar, R.E., E-mail: amritkar@prl.res.in [Physical Research Laboratory, Ahmedabad 380 009 (India)

    2011-11-15

    Highlights: > Delay and anticipation in coupling function varies with system dynamics. > Delay or anticipation of the synchronized state is independent of system delay. > Stability analysis developed is quite general. > We demonstrate enhanced security in communication. > Generalized synchronization possible over a wide range of parameter mismatch. - Abstract: We present a mechanism for synchronizing time delay systems using one way coupling with a variable delay in coupling that is reset at finite intervals. We present the analysis of the error dynamics that helps to isolate regions of stability of the synchronized state in the parameter space of interest for single and multiple delays. We supplement this by numerical simulations in a standard time delay system like Mackey Glass system. This method has the advantage that it can be adjusted to be delay or anticipatory in synchronization with a time which is independent of the system delay. We demonstrate the use of this method in communication using the bi channel scheme. We show that since the synchronizing channel carries information from transmitter only at intervals of reset time, it is not susceptible to an easy reconstruction.

  4. The effect of growing regions, microbiological fertilizers and soil additives on productivity of buckwheat (Fagopyrum esculentum Moench)

    OpenAIRE

    Dolijanović Željko K.; Oljača Snežana I.; Kovačević Dušan Đ.; Šeremešić Srđan I.; Jovović Zoran M.

    2014-01-01

    This study was aimed at investigating the productivity of buckwheat taking into account growing regions, especially altitude, since this species does not have demanding soil requirements. The experiments were conducted during 2009 and 2010 in two localities: Valjevo (the village of Jasenica at 300 m altitude - 2009 and the village of Jovanja at 160 m altitude - 2010), and Nova Varos (the village of Radijevići at 1,065 m altitude). Soil of the experimental p...

  5. Optimum Delayed Retirement Credit

    OpenAIRE

    Sheshinski, Eytan

    2002-01-01

    A central question for pension design is how benefits should vary with the age of retirement beyond early eligibility age. It is often argued that in order to be neutral with respect to individual retirement decisions benefits should be actuarially fair, that is, the present value of additional contributions and benefits (’Delayed Retirement Credit’ - DRC) due to postponed retirement should be equal. We show that in a self-selection, asymmetric information model, because individual decisions ...

  6. Permissible Delay in Payments

    Directory of Open Access Journals (Sweden)

    Yung-Fu Huang

    2007-01-01

    Full Text Available The main purpose of this paper wants to investigate the optimal retailer's lot-sizing policy with two warehouses under partially permissible delay in payments within the economic order quantity (EOQ framework. In this paper, we want to extend that fully permissible delay in payments to the supplier would offer the retailer partially permissible delay in payments. That is, the retailer must make a partial payment to the supplier when the order is received. Then the retailer must pay off the remaining balance at the end of the permissible delay period. In addition, we want to add the assumption that the retailer's storage space is limited. That is, the retailer will rent the warehouse to store these exceeding items when the order quantity is larger than retailer's storage space. Under these conditions, we model the retailer's inventory system as a cost minimization problem to determine the retailer's optimal cycle time and optimal order quantity. Three theorems are developed to efficiently determine the optimal replenishment policy for the retailer. Finally, numerical examples are given to illustrate these theorems and obtained a lot of managerial insights.

  7. Best Linear Unbiased Prediction (BLUP) for regional yield trials: a comparison to additive main effects and multiplicative interaction (AMMI) analysis.

    Science.gov (United States)

    Piepho, H P

    1994-11-01

    Multilocation trials are often used to analyse the adaptability of genotypes in different environments and to find for each environment the genotype that is best adapted; i.e. that is highest yielding in that environment. For this purpose, it is of interest to obtain a reliable estimate of the mean yield of a cultivar in a given environment. This article compares two different statistical estimation procedures for this task: the Additive Main Effects and Multiplicative Interaction (AMMI) analysis and Best Linear Unbiased Prediction (BLUP). A modification of a cross validation procedure commonly used with AMMI is suggested for trials that are laid out as a randomized complete block design. The use of these procedure is exemplified using five faba bean datasets from German registration trails. BLUP was found to outperform AMMI in four of five faba bean datasets.

  8. Systematics in delayed neutron yields

    Energy Technology Data Exchange (ETDEWEB)

    Ohsawa, Takaaki [Kinki Univ., Higashi-Osaka, Osaka (Japan). Atomic Energy Research Inst.

    1998-03-01

    An attempt was made to reproduce the systematic trend observed in the delayed neutron yields for actinides on the basis of the five-Gaussian representation of the fission yield together with available data sets for delayed neutron emission probability. It was found that systematic decrease in DNY for heavier actinides is mainly due to decrease of fission yields of precursors in the lighter side of the light fragment region. (author)

  9. An examination of the origin and evolution of additional tandem repeats in the mitochondrial DNA control region of Japanese sika deer (Cervus Nippon).

    Science.gov (United States)

    Ba, Hengxing; Wu, Lang; Liu, Zongyue; Li, Chunyi

    2016-01-01

    Tandem repeat units are only detected in the left domain of the mitochondrial DNA control region in sika deer. Previous studies showed that Japanese sika deer have more tandem repeat units than its cousins from the Asian continent and Taiwan, which often have only three repeat units. To determine the origin and evolution of these additional repeat units in Japanese sika deer, we obtained the sequence of repeat units from an expanded dataset of the control region from all sika deer lineages. The functional constraint is inferred to act on the first repeat unit because this repeat has the least sequence divergence in comparison to the other units. Based on slipped-strand mispairing mechanisms, the illegitimate elongation model could account for the addition or deletion of these additional repeat units in the Japanese sika deer population. We also report that these additional repeat units could be occurring in the internal positions of tandem repeat regions, possibly via coupling with a homogenization mechanism within and among these lineages. Moreover, the increased number of repeat units in the Japanese sika deer population could reflect a balance between mutation and selection, as well as genetic drift.

  10. Beta-decay half-lives and beta-delayed neutron emisison probabilities of nuclei in the region A. 110, relevant for the r-process

    Energy Technology Data Exchange (ETDEWEB)

    Moller, Peter [Los Alamos National Laboratory; Pereira, J [MSU; Hennrich, S [MSU; Aprahamian, A [UNIV OF NOTRE DAME; Arndt, O [GERMANY; Becerril, A [MSU; Elliot, T [MSU; Estrade, A [MSU; Galaviz, D [MSU; Kessler, R [UNIV MAINZ; Kratz, K - L [GERMANY; Lorusso, G [MSU; Mantica, P F [MSU; Matos, M [MSU; Montes, F [MSU; Pfeiffer, B [UNIV MAINZ; Schatz, F [MSU; Schnorrenberger, L [GERMANY; Smith, E [MSU; Stolz, A [MSU; Quinn, M [UNIV OF NOTRE DAME; Walters, W B [UNIV OF MARYLAND; Wohr, A [UNIV OF NOTRE DAME

    2009-01-01

    Measurements of the {beta}-decay properties of A {approx}< 110 r-process nuclei have been completed at the National Superconducting Cyclotron Laboratory, at Michigan State University. {beta}-decay half-lives for {sup 105}Y, {sup 106,107}Zr and {sup 108,111}Mo, along with ,B-delayed neutron emission probabilities of 104Y, 109,11OMo and upper limits for 105Y, 103-107Zr and 108,111 Mo have been measured for the first time. Studies on the basis of the quasi-random phase approximation are used to analyze the ground-state deformation of these nuclei.

  11. CAN LARGE TIME DELAYS OBSERVED IN LIGHT CURVES OF CORONAL LOOPS BE EXPLAINED IN IMPULSIVE HEATING?

    Energy Technology Data Exchange (ETDEWEB)

    Lionello, Roberto; Linker, Jon A.; Mikić, Zoran [Predictive Science, Inc., 9990 Mesa Rim Rd., Ste. 170, San Diego, CA 92121-3933 (United States); Alexander, Caroline E.; Winebarger, Amy R., E-mail: lionel@predsci.com, E-mail: linkerj@predsci.com, E-mail: mikicz@predsci.com, E-mail: caroline.e.alexander@nasa.gov, E-mail: amy.r.winebarger@nasa.gov [NASA Marshall Space Flight Center, ZP 13, Huntsville, AL 35805 (United States)

    2016-02-20

    The light curves of solar coronal loops often peak first in channels associated with higher temperatures and then in those associated with lower temperatures. The delay times between the different narrowband EUV channels have been measured for many individual loops and recently for every pixel of an active region observation. The time delays between channels for an active region exhibit a wide range of values. The maximum time delay in each channel pair can be quite large, i.e., >5000 s. These large time delays make-up 3%–26% (depending on the channel pair) of the pixels where a trustworthy, positive time delay is measured. It has been suggested that these time delays can be explained by simple impulsive heating, i.e., a short burst of energy that heats the plasma to a high temperature, after which the plasma is allowed to cool through radiation and conduction back to its original state. In this paper, we investigate whether the largest observed time delays can be explained by this hypothesis by simulating a series of coronal loops with different heating rates, loop lengths, abundances, and geometries to determine the range of expected time delays between a set of four EUV channels. We find that impulsive heating cannot address the largest time delays observed in two of the channel pairs and that the majority of the large time delays can only be explained by long, expanding loops with photospheric abundances. Additional observations may rule out these simulations as an explanation for the long time delays. We suggest that either the time delays found in this manner may not be representative of real loop evolution, or that the impulsive heating and cooling scenario may be too simple to explain the observations, and other potential heating scenarios must be explored.

  12. Source Coding When the Side Information May Be Delayed

    CERN Document Server

    Simeone, Osvaldo

    2011-01-01

    For memoryless sources, delayed side information at the decoder does not improve the rate-distortion function. However, this is not the case for more general sources with memory, as demonstrated by a number of works focusing on the special case of (delayed) feedforward. In this paper, a setting is studied in which the encoder is potentially uncertain about the delay with which measurements of the side information are acquired at the decoder. Assuming a hidden Markov model for the sources, at first, a single-letter characterization is given for the set-up where the side information delay is arbitrary and known at the encoder, and the reconstruction at the destination is required to be (near) lossless. Then, with delay equal to zero or one source symbol, a single-letter characterization is given of the rate-distortion region for the case where side information may be delayed or not, unbeknownst to the encoder. The characterization is further extended to allow for additional information to be sent when the side ...

  13. 山地延迟番茄晚疫病的发生与防治%Occurrence and Prevention of Delay Tomato Late Blight in Mountainous Region

    Institute of Scientific and Technical Information of China (English)

    李景明

    2015-01-01

    Symptom expression,etiology,occurred conditions of tomato late blight were elabrated.Causes of the outbreak on tomato late blight were analyzed.And in view of the characteristics of tomato late blight,prevention measures were put forward,so as to provide reference for delay tomato growers to forecast and prevention of the disease in Qingzhen City.%阐述了番茄晚疫病症状表现尧病原尧发生条件,分析该病重发原因,并针对番茄晚疫病的危害特点,提出防治措施,以期为清镇市延迟番茄种植户预测和防治该病提供参考。

  14. Stabilisation for switched linear systems with time-varying delay and input saturation

    Science.gov (United States)

    Chen, Yonggang; Fei, Shumin; Zhang, Kanjian

    2014-03-01

    This article investigates the stabilisation problems for continuous-time and discrete-time switched systems with time-varying delay and saturated control input. Based on dwell time switching signals and multiple Lyapunov functional method, stabilisation conditions are well obtained in the context of linear matrix inequalities. To estimate attractive regions as large as possible, the feasibility problems are translated into optimisation problems. In addition, the corresponding results are presented for linear time-delay systems and switched delay-free systems, which improve and supplement some existing ones in the literature. Finally, numerical examples and simulations are given to illustrate the effectiveness and values of the proposed results.

  15. Effective multicasting algorithm for dynamic membership with delay constraint

    Institute of Scientific and Technical Information of China (English)

    CHEN Lin; XU Zheng-quan

    2006-01-01

    This paper proposes an effective heuristic algorithm for dynamic multicast routing with delay-constrained DDMR.The tree constructed by DDMR has the following characteristics: (1) multicast tree changes with the dynamic memberships; (2)the cost of the tree is as small as possible at each node addition/removal event; (3) all of the path delay meet a fixed delay constraint;(4) minimal perturbation to an existing tree. The proposed algorithm is based on "damage" and "usefulness" concepts proposed in previous work, and has a new parameter bf(Balancing Factor) for judging whether or not to rearrange a tree region when membership changes. Mutation operation in Genetic Algorithm (GA) is also employed to find an attached node for a new adding node.Simulation showed that our algorithm performs well and is better than static heuristic algorithms, in term of cost especially.

  16. Dissipative Control of the State Delayed Systems

    Institute of Scientific and Technical Information of China (English)

    FU Yu-sun; TIAN Zuo-hua; SHI Song-jiao

    2001-01-01

    In this note, the dissipative control problem of the general quadratic supply rate for state delayed systems is considered. A systematic approach is used in this work so that a sufficient condition on the existence of a delay-independent state feedback controller is given. In addition, a sufficient condition on the existence of a delay-dependent state feedback is presented. Our solutions are expressed in terms of matrix inequalities that can be solved by numerical method. The delay-dependent controller might be less conservative than the delay-independent one in the sense that the delay-dependent case may have a solution for a larger class of systems than that for delay-independent case.

  17. Sloppy Addition and Multiplication

    DEFF Research Database (Denmark)

    Nannarelli, Alberto

    Sometimes reducing the precision of a numerical processor, by introducing errors, can lead to significant performance (delay, area and power dissipation) improvements without compromising the overall quality of the processing. In this work, we show how to perform the two basic operations, addition...

  18. Facilitating tolerance of delayed reinforcement during functional communication training.

    Science.gov (United States)

    Fisher, W W; Thompson, R H; Hagopian, L P; Bowman, L G; Krug, A

    2000-01-01

    Few clinical investigations have addressed the problem of delayed reinforcement. In this investigation, three individuals whose destructive behavior was maintained by positive reinforcement were treated using functional communication training (FCT) with extinction (EXT). Next, procedures used in the basic literature on delayed reinforcement and self-control (reinforcer delay fading, punishment of impulsive responding, and provision of an alternative activity during reinforcer delay) were used to teach participants to tolerate delayed reinforcement. With the first case, reinforcer delay fading alone was effective at maintaining low rates of destructive behavior while introducing delayed reinforcement. In the second case, the addition of a punishment component reduced destructive behavior to near-zero levels and facilitated reinforcer delay fading. With the third case, reinforcer delay fading was associated with increases in masturbation and head rolling, but prompting and praising the individual for completing work during the delay interval reduced all problem behaviors and facilitated reinforcer delay fading.

  19. Facilitating tolerance of delayed reinforcement during functional communication training.

    Science.gov (United States)

    Fisher, W W; Thompson, R H; Hagopian, L P; Bowman, L G; Krug, A

    2000-01-01

    Few clinical investigations have addressed the problem of delayed reinforcement. In this investigation, three individuals whose destructive behavior was maintained by positive reinforcement were treated using functional communication training (FCT) with extinction (EXT). Next, procedures used in the basic literature on delayed reinforcement and self-control (reinforcer delay fading, punishment of impulsive responding, and provision of an alternative activity during reinforcer delay) were used to teach participants to tolerate delayed reinforcement. With the first case, reinforcer delay fading alone was effective at maintaining low rates of destructive behavior while introducing delayed reinforcement. In the second case, the addition of a punishment component reduced destructive behavior to near-zero levels and facilitated reinforcer delay fading. With the third case, reinforcer delay fading was associated with increases in masturbation and head rolling, but prompting and praising the individual for completing work during the delay interval reduced all problem behaviors and facilitated reinforcer delay fading. PMID:10641365

  20. Time Interference Alignment via Delay Offset for Long Delay Networks

    CERN Document Server

    Blasco, Francisco Lazaro; Bauch, Gerhard

    2011-01-01

    Time Interference Alignment is a flavor of Interference Alignment that increases the network capacity by suitably staggering the transmission delays of the senders. In this work the analysis of the existing literature is generalized and the focus is on the computation of the dof for networks with randomly placed users in a n-dimensional Euclidean space. In the basic case without coordination among the transmitters analytical expressions of the sum dof can be derived. If the transmit delays are coordinated, in 20% of the cases time Interference Alignment yields additional dof with respect to orthogonal access schemes. The potential capacity improvements for satellite networks are also investigated.

  1. Coherent Pattern Prediction in Swarms of Delay-Coupled Agents

    Science.gov (United States)

    Mier-Y-Teran-Romero, Luis; Forgoston, Eric; Scwartz, Ira

    2013-03-01

    We consider a general swarm model of self-propelling particles interacting through a pairwise potential in the presence of a fixed communication time delay. Previous work has shown that swarms with communication time delays and noise may display pattern transitions that depend on the size of the coupling amplitude. We extend these results by completely unfolding the bifurcation structure of the mean field approximation. Our analysis reveals a direct correspondence between the different dynamical behaviors found in different regions of the coupling-time delay plane with the different classes of simulated coherent swarm patterns. We derive the spatio-temporal scales of the swarm structures, and also demonstrate how the complicated interplay of coupling strength, time delay, noise intensity, and choice of initial conditions can affect the swarm. In addition, when adding noise to the system, we find that for sufficiently large values of the coupling strength and/or the time delay, there is a noise intensity threshold that forces a transition of the swarm from a misaligned state into an aligned state. We show that this alignment transition exhibits hysteresis when the noise intensity is taken to be time dependent. Office of Naval Research, NIH (LMR and IBS) and NRL (EF)

  2. Can the addition of regional radiotherapy counter-balance important risk factors in breast cancer patients with extracapsular invasion of axillary lymph-node metastases?

    International Nuclear Information System (INIS)

    Purpose: To evaluate if locoregional radiotherapy (RT) versus local irradiation only can alter the pattern of failure in breast cancer patients with extranodal invasion. Patients and Methods: From 08/1988 to 06/1998, 81 patients with extranodal invasion were treated with adjuvant RT (median total dose: 50.4 Gy), 46/81 only locally, 35/81 locoregionally due to presumed adverse parameters. The mean number of resected (positive) lymph nodes was 17 (seven). 78 patients received adjuvant systemic treatment(s). Results: Patients treated with locoregional RT had significantly more often lymphatic vessel invasion (LVI; 63% vs. 28%; p = 0.003), T3/T4 tumors (43% vs. 17%; p = 0.014), and four or more positive lymph nodes (91% vs. 46%; p < 0.001) than patients irradiated only locally. Disease progression occurred in 24/81 patients (locoregional RT: 26% vs. local RT: 33%). The above risk factors were highly significant of worse outcome. Despite their overrepresentation in the locoregional RT group, no difference was found between both groups in regard to disease-free survival (DFS; p = 0.83) and overall survival (OS; p = 0.56), suggesting that regional RT was able to counterbalance the increased risk. There was even a trend toward a better 3-year DFS, 61% in locoregional RT and 37% in local RT, in the subgroup of patients with four or more positive lymph nodes. In a Cox regression model, higher T-stage, four or more positive lymph nodes, and LVI remained significant. For DFS and distant metastasis-free survival (DMFS), the absence of estrogen receptors and the omission of regional RT were also significant. Conclusion: Our data suggest that the addition of regional RT might be beneficial in selected subgroups of patients with extranodal invasion and other poor prognostic factors. (orig.)

  3. Delaying vortex breakdown by waves

    Science.gov (United States)

    Yao, M. F.; Jiang, L. B.; Wu, J. Z.; Ma, H. Y.; Pan, J. Y.

    1989-03-01

    The effect of spiral waves on delaying vortex breakdown in a tube is studied experimentally and theoretically. When a harmonic oscillation was imposed on one of guiding vanes in the tube, the breakdown was observed to be postponed appreciately. According to the generalized Lagrangian mean theory, proper forcing spiral waves may produce an additional streaming momentum, of which the effect is favorable and similar to an axial suction at downstream end. The delayed breakdown position is further predicted by using nonlinear wave theory. Qualitative agreement between theory and experiment is obtained, and experimental comparison of the effects due to forcing spiral wave and axial suction is made.

  4. Delays in the management of retroperitoneal sarcomas

    DEFF Research Database (Denmark)

    Seinen, Jojanneke; Almquist, Martin; Styring, Emelie;

    2010-01-01

    at the general practitioner, 36 days at local hospitals, and 55 days at the sarcoma centre. Conclusion. Centralization per se is not sufficient for optimized and efficient management. Our findings suggest that delays can be minimized by direct referral of patients from primary health care to sarcoma centers...... sarcoma in the southern Sweden health care region 2003-2009 were eligible for the study. Data on referrals and diagnostic investigations were collected from clinical files from primary health care, local hospitals, and from the sarcoma centre. Lead times were divided into patient delays and health care...... delays caused by primary health care, local hospitals, or procedures at the sarcoma centre. Results. Complete data were available from 33 patients and demonstrated a median patient delay of 23 days (0-17 months) and median health care delay of 94 days (1-40 months) with delays of median 15 days...

  5. Delay Time in Quaternionic Quantum Mechanics

    CERN Document Server

    De Leo, Stefano

    2012-01-01

    In looking for quaternionic violations of quantum mechanics, we discuss the delay time for pure quaternionic potentials. The study shows in which energy region it is possible to amplify the difference between quaternionic and complex quantum mechanics.

  6. Relative impact of previous disturbance history on the likelihood of additional disturbance in the Northern United States Forest Service USFS Region

    Science.gov (United States)

    Hernandez, A. J.

    2015-12-01

    The Landsat archive is increasingly being used to detect trends in the occurrence of forest disturbance. Beyond information about the amount of area affected, forest managers need to know if and how disturbance regimes change. The National Forest System (NFS) has developed a comprehensive plan for carbon monitoring that requires a detailed temporal mapping of forest disturbances across 75 million hectares. A long-term annual time series that shows the timing, extent, and type of disturbance beginning in 1990 and ending in 2011 has been prepared for several USFS Regions, including the Northern Region. Our mapping starts with an automated detection of annual disturbances using a time series of historical Landsat imagery. Automated detections are meticulously inspected, corrected and labeled using various USFS ancillary datasets. The resulting maps of verified disturbance show the timing and types are fires, harvests, insect activity, disease, and abiotic (wind, drought, avalanche) damage. Also, the magnitude of each change event is modeled in terms of the proportion of canopy cover lost. The sequence of disturbances for every pixel since 1990 has been consistently mapped and is available across the entirety of NFS. Our datasets contain sufficient information to describe the frequency of stand replacement, as well as how often disturbance results in only a partial loss of canopy. This information provides empirical insight into how an initial disturbance may predispose a stand to further disturbance, and it also show a climatic signal in the occurrence of processes such as fire and insect epidemics. Thus, we have the information to model the likelihood of occurrence of certain disturbances after a given event (i.e. if we have a fire in the past what does that do to the likelihood of occurrence of insects in the future). Here, we explore if previous disturbance history is a reliable predictor of additional disturbance in the future and we present results of applying

  7. Dimensional reduction of nonlinear time delay systems

    Directory of Open Access Journals (Sweden)

    M. S. Fofana

    2005-01-01

    infinite-dimensional problem without the assumption of small time delay. This dimensional reduction is illustrated in this paper with the delay versions of the Duffing and van der Pol equations. For both nonlinear delay equations, transcendental characteristic equations of linearized stability are examined through Hopf bifurcation. The infinite-dimensional nonlinear solutions of the delay equations are decomposed into stable and centre subspaces, whose respective dimensions are determined by the linearized stability of the transcendental equations. Linear semigroups, infinitesimal generators, and their adjoint forms with bilinear pairings are the additional candidates for the infinite-dimensional reduction.

  8. Time delay and long-range connection induced synchronization transitions in Newman-Watts small-world neuronal networks.

    Science.gov (United States)

    Qian, Yu

    2014-01-01

    The synchronization transitions in Newman-Watts small-world neuronal networks (SWNNs) induced by time delay τ and long-range connection (LRC) probability P have been investigated by synchronization parameter and space-time plots. Four distinct parameter regions, that is, asynchronous region, transition region, synchronous region, and oscillatory region have been discovered at certain LRC probability P = 1.0 as time delay is increased. Interestingly, desynchronization is observed in oscillatory region. More importantly, we consider the spatiotemporal patterns obtained in delayed Newman-Watts SWNNs are the competition results between long-range drivings (LRDs) and neighboring interactions. In addition, for moderate time delay, the synchronization of neuronal network can be enhanced remarkably by increasing LRC probability. Furthermore, lag synchronization has been found between weak synchronization and complete synchronization as LRC probability P is a little less than 1.0. Finally, the two necessary conditions, moderate time delay and large numbers of LRCs, are exposed explicitly for synchronization in delayed Newman-Watts SWNNs.

  9. Delayed translational silencing of ceruloplasmin transcript in gamma interferon-activated U937 monocytic cells: role of the 3' untranslated region

    Science.gov (United States)

    Mazumder, B.; Fox, P. L.

    1999-01-01

    Ceruloplasmin (Cp) is an acute-phase protein with ferroxidase, amine oxidase, and pro- and antioxidant activities. The primary site of Cp synthesis in human adults is the liver, but it is also synthesized by cells of monocytic origin. We have shown that gamma interferon (IFN-gamma) induces the synthesis of Cp mRNA and protein in monocytic cells. We now report that the induced synthesis of Cp is terminated by a mechanism involving transcript-specific translational repression. Cp protein synthesis in U937 cells ceased after 16 h even in the presence of abundant Cp mRNA. RNA isolated from cells treated with IFN-gamma for 24 h exhibited a high in vitro translation rate, suggesting that the transcript was not defective. Ribosomal association of Cp mRNA was examined by sucrose centrifugation. When Cp synthesis was high, i.e., after 8 h of IFN-gamma treatment, Cp mRNA was primarily associated with polyribosomes. However, after 24 h, when Cp synthesis was low, Cp mRNA was primarily in the nonpolyribosomal fraction. Cytosolic extracts from cells treated with IFN-gamma for 24 h, but not for 8 h, contained a factor which blocked in vitro Cp translation. Inhibitor expression was cell type specific and present in extracts of human cells of myeloid origin, but not in several nonmyeloid cells. The inhibitory factor bound to the 3' untranslated region (3'-UTR) of Cp mRNA, as shown by restoration of in vitro translation by synthetic 3'-UTR added as a "decoy" and detection of a binding complex by RNA gel shift analysis. Deletion mapping of the Cp 3'-UTR indicated an internal 100-nucleotide region of the Cp 3'-UTR that was required for complex formation as well as for silencing of translation. Although transcript-specific translational control is common during development and differentiation and global translational control occurs during responses to cytokines and stress, to our knowledge, this is the first report of translational silencing of a specific transcript following cytokine

  10. Delay in onset of metabolic alkalosis during regional citrate anti-coagulation in continous renal replacement therapy with calcium-free replacement solution

    Directory of Open Access Journals (Sweden)

    See Kay

    2009-01-01

    Full Text Available Regional citrate anti-coagulation for continuous renal replacement therapy chelates calcium to produce the anti- coagulation effect. We hypothesise that a calcium-free replacement solution will require less citrate and produce fewer metabolic side effects. Fifty patients, in a Medical Intensive Care Unit of a tertiary teaching hospital (25 in each group, received continuous venovenous hemofiltration using either calcium-containing or calcium-free replacement solutions. Both groups had no significant differences in filter life, metabolic alkalosis, hypernatremia, hypocalcemia, and hypercalcemia. However, patients using calcium-containing solution developed metabolic alkalosis earlier, compared to patients using calcium-free solution (mean 24.6 hours,CI 0.8-48.4 vs. 37.2 hours, CI 9.4-65, P = 0.020. When calcium-containing replacement solution was used, more citrate was required (mean 280ml/h, CI 227.2-332.8 vs. 265ml/h, CI 203.4-326.6, P = 0.069, but less calcium was infused (mean 21.2 ml/h, CI 1.2-21.2 vs 51.6ml/h, CI 26.8-76.4, P ≤ 0.0001.

  11. Effects of Addition of Systemic Tramadol or Adjunct Tramadol to Lidocaine Used for Intravenous Regional Anesthesia in Patients Undergoing Hand Surgery.

    Science.gov (United States)

    Yektaş, Abdulkadir; Gümüş, Funda; Karayel, Abdulhalim; Alagöl, Ayşin

    2016-01-01

    Intravenous regional anesthesia (IVRA) is used in outpatient hand surgery as an easily applicable and cost-effective technique with clinical advantages. The present study aimed to investigate the effects of addition of systemic tramadol or adjunct tramadol to lidocaine for IVRA in patients undergoing hand surgery. American Society of Anesthesiologists (ASA) I-II patients (n = 60) who underwent hand surgery were included. For this purpose, only lidocaine (LDC), lidocaine+adjunct tramadol (LDC+TRA group), or lidocaine+systemic tramadol (LDC+SysTRA group) was administered to the patients for IVRA and the groups were compared in terms of onset and recovery time of sensory and motor blocks, quality of anesthesia, and the degree of intraoperative and postoperative pain. The onset time of sensorial block was significantly shorter in the LDC+TRA group than that in the LDC+SysTRA group. The motor block recovery time was significantly shorter in the LDC+SysTRA group than that in the LDC+TRA and LDC groups. Administration of tramadol as an adjunct showed some clinical benefits by providing a shorter onset time of sensory and motor block, decreasing pain and analgesic requirement, and improving intraoperative conditions during IVRA. It was determined that systemic tramadol administration had no superiority.

  12. Effects of Addition of Systemic Tramadol or Adjunct Tramadol to Lidocaine Used for Intravenous Regional Anesthesia in Patients Undergoing Hand Surgery

    Directory of Open Access Journals (Sweden)

    Abdulkadir Yektaş

    2016-01-01

    Full Text Available Intravenous regional anesthesia (IVRA is used in outpatient hand surgery as an easily applicable and cost-effective technique with clinical advantages. The present study aimed to investigate the effects of addition of systemic tramadol or adjunct tramadol to lidocaine for IVRA in patients undergoing hand surgery. American Society of Anesthesiologists (ASA I-II patients (n=60 who underwent hand surgery were included. For this purpose, only lidocaine (LDC, lidocaine+adjunct tramadol (LDC+TRA group, or lidocaine+systemic tramadol (LDC+SysTRA group was administered to the patients for IVRA and the groups were compared in terms of onset and recovery time of sensory and motor blocks, quality of anesthesia, and the degree of intraoperative and postoperative pain. The onset time of sensorial block was significantly shorter in the LDC+TRA group than that in the LDC+SysTRA group. The motor block recovery time was significantly shorter in the LDC+SysTRA group than that in the LDC+TRA and LDC groups. Administration of tramadol as an adjunct showed some clinical benefits by providing a shorter onset time of sensory and motor block, decreasing pain and analgesic requirement, and improving intraoperative conditions during IVRA. It was determined that systemic tramadol administration had no superiority.

  13. Second Malignancies After Adjuvant Radiation Therapy for Early Stage Breast Cancer: Is There Increased Risk With Addition of Regional Radiation to Local Radiation?

    International Nuclear Information System (INIS)

    Purpose: This study was undertaken to determine whether there was an increased risk of second malignancies (SM), particularly lung cancer, in early stage breast cancer patients treated with the addition of nodal fields to breast and/or chest wall radiation therapy (RT). Materials and Methods: Subjects were stage I/II female breast cancer patients 20 to 79 years of age, diagnosed between 1989 and 2005 and treated with adjuvant RT at our institution. Patients were included if they survived and did not have SM within 3 years of diagnosis. Standardized incidence ratios (SIR) with 95% confidence intervals (CI) were calculated to compare SM incidence to cancer incidence in the general sex- and age-matched populations. Secondary malignancy risks in patients treated with local RT (LRT) to the breast/chest wall were compared to those in patients treated with locoregional RT (LRRT) to the breast/chest wall and regional nodes, using multivariate regression analysis (MVA) to account for covariates. Results: The cohort included 12,836 patients with a median follow-up of 8.4 years. LRRT was used in 18% of patients. The SIR comparing patients treated with LRT to the general population was 1.29 (CI: 1.21-1.38). No statistically significant increased incidence of in-field malignancies (SIR, 1.04; CI: 0.87-1.23) and lung cancers (SIR, 1.06; CI: 0.88-1.26) was detected. The SIR comparing patients treated with LRRT to the general population was 1.39 (CI: 1.17-1.64). No statistically significant increased incidence of in-field malignancies (SIR, 1.26; CI: 0.77-1.94) and lung cancers (SIR, 1.27; CI: 0.76-1.98) was detected. On MVA comparing LRRT to LRT, the adjusted hazard ratio was 1.20 for in-field malignancies (CI: 0.68-2.16) and 1.26 for lung cancer (CI: 0.67-2.36). The excess attributable risk (EAR) to regional RT was 3.1 per 10,000 person years (CI: −8.7 to 9.9). Conclusions: No statistically significant increased risk of second malignancy was detected after LRRT relative to

  14. Delayed Gambler's Ruin

    CERN Document Server

    Imai, Tomohisa

    2016-01-01

    We present here a new extended model of the gambler's ruin problem by incorporating delays in receiving of rewards and paying of penalties. When there is a difference between two delays, an exact analysis of the ruin probability is difficult. We derive an approximate scheme to find an effective shift in the initial assets of the gambler. Through comparison against computer simulations, this approximation is shown to work for small differences between the two delays.

  15. Controlling a time-delay system using multiple delay feedback control

    Institute of Scientific and Technical Information of China (English)

    Qi Wei; Zhang Yan; Wang Ying-Hai

    2007-01-01

    In this paper multiple delay feedback control (MDFC) with different and independent delay times is shown to be an efficient method for stabilizing fixed points in finite-dimensional dynamical systems. Whether MDFC can be applied to infinite-dimensional systems has been an open question. In this paper we find that for infinite-dimensional systems modelled by delay differential equations, MDFC works well for stabilizing (unstable) steady states in long-, moderate-and short-time delay regions, in particular for the hyperchaotic case.

  16. VARIABLE TIME DELAY MEANS

    Science.gov (United States)

    Clemensen, R.E.

    1959-11-01

    An electrically variable time delay line is described which may be readily controlled simuitaneously with variable impedance matching means coupied thereto such that reflections are prevented. Broadly, the delay line includes a signal winding about a magnetic core whose permeability is electrically variable. Inasmuch as the inductance of the line varies directly with the permeability, the time delay and characteristic impedance of the line both vary as the square root of the permeability. Consequently, impedance matching means may be varied similariy and simultaneously w:th the electrically variable permeability to match the line impedance over the entire range of time delay whereby reflections are prevented.

  17. VideoLat: An Extensible Tool for Multimedia Delay Measurements

    NARCIS (Netherlands)

    Jansen, A.J.

    2014-01-01

    When using a videoconferencing system there will always be a delay from sender to receiver. Such delays affect human communication, and therefore knowing the delay is a major factor in judging the expected quality of experience of the conferencing system. Additionally, for implementors, tuning the s

  18. Improved LMI representations for delay-independent and delay-dependent stability conditions

    Institute of Scientific and Technical Information of China (English)

    Yingmin JIA; Hideki Kokame

    2003-01-01

    Some new linear matrix inequality (LMI) representations for deley-independent and delay-dependent stability conditions are obtained by introducing additional matrices and eliminating the product coupling of the system matrices and the Lyapunov matrices. The results improve conservativeness of the given conditions for the analysis and the design of time-delay systems with polytopic-type uncertainty.

  19. Delay Banking for Managing Air Traffic

    Science.gov (United States)

    Green, Steve

    2008-01-01

    Delay banking has been invented to enhance air-traffic management in a way that would increase the degree of fairness in assigning arrival, departure, and en-route delays and trajectory deviations to aircraft impacted by congestion in the national airspace system. In delay banking, an aircraft operator (airline, military, general aviation, etc.) would be assigned a numerical credit when any of their flights are delayed because of an air-traffic flow restriction. The operator could subsequently bid against other operators competing for access to congested airspace to utilize part or all of its accumulated credit. Operators utilize credits to obtain higher priority for the same flight, or other flights operating at the same time, or later, in the same airspace, or elsewhere. Operators could also trade delay credits, according to market rules that would be determined by stakeholders in the national airspace system. Delay banking would be administered by an independent third party who would use delay banking automation to continually monitor flights, allocate delay credits, maintain accounts of delay credits for participating airlines, mediate bidding and the consumption of credits of winning bidders, analyze potential transfers of credits within and between operators, implement accepted transfers, and ensure fair treatment of all participating operators. A flow restriction can manifest itself in the form of a delay in assigned takeoff time, a reduction in assigned airspeed, a change in the position for the aircraft in a queue of all aircraft in a common stream of traffic (e.g., similar route), a change in the planned altitude profile for an aircraft, or change in the planned route for the aircraft. Flow restrictions are typically imposed to mitigate traffic congestion at an airport or in a region of airspace, particularly congestion due to inclement weather, or the unavailability of a runway or region of airspace. A delay credit would be allocated to an operator of a

  20. Discovery of a Plains Caldera Complex and Extinct Lava Lake in Arabia Terra, Mars: Implications for the Discovery of Additional Highland Volcanic Source Regions

    Science.gov (United States)

    Bleacher, Jacob; Michalski, Joseph

    2012-01-01

    Several irregularly shaped topographic depressions occur near the dichotomy boundary in northern Arabia Terra, Mars. The geomorphology of these features suggests that they formed by collapse, opposed to meteor impact. At least one depression (approx.55 by 85 km) displays geologic features indicating a complex, multi-stage collapse history. Features within and around the collapse structure indicate volcanic processes. The complex occurs within Hesperian ridged plains of likely volcanic origin and displays no crater rim or evidence for ejecta. Instead the depression consists of a series of circumferential graben and down-dropped blocks which also display upper surfaces similar to ridged plain lavas. Large blocks within the depression are tilted towards the crater center, and display graben that appear to have originally been linked with circumferential graben outside of the complex related to earlier collapse events. A nearly 700 m high mound exists along a graben within the complex that might be a vent. The deepest depression displays two sets of nearly continuous terraces, which we interpret as high-stands of a drained lava lake. These features appear similar to the black ledge described during the Kilauea Iki eruption in 1959. A lacustrine origin for the terraces seems unlikely because of the paucity of channels found in or around the depression that could be linked to aqueous surface processes. In addition, there is no obvious evidence for lacustrine sediments within the basin. Together with the presence of significant faulting that is indicative of collapse we conclude that this crater complex represents a large caldera formed in the Late Noachian to Early Hesperian. Other linear and irregular depressions in the region also might be linked to ancient volcanism. If that hypothesis is correct, it suggests that northern Arabia Terra could contain a large, previously unrecognized highland igneous province. Evacuation of magma via explosive and effusive activity

  1. Dynamic Network Delay Cartography

    CERN Document Server

    Rajawat, Ketan; Giannakis, Georgios B

    2012-01-01

    Path delays in IP networks are important metrics, required by network operators for assessment, planning, and fault diagnosis. Monitoring delays of all source-destination pairs in a large network is however challenging and wasteful of resources. The present paper advocates a spatio-temporal Kalman filtering approach to construct network-wide delay maps using measurements on only a few paths. The proposed network cartography framework allows efficient tracking and prediction of delays by relying on both topological as well as historical data. Optimal paths for delay measurement are selected in an online fashion by leveraging the notion of submodularity. The resulting predictor is optimal in the class of linear predictors, and outperforms competing alternatives on real-world datasets.

  2. Recovery of delay time from time series based on the nearest neighbor method

    Science.gov (United States)

    Prokhorov, M. D.; Ponomarenko, V. I.; Khorev, V. S.

    2013-12-01

    We propose a method for the recovery of delay time from time series of time-delay systems. The method is based on the nearest neighbor analysis. The method allows one to reconstruct delays in various classes of time-delay systems including systems of high order, systems with several coexisting delays, and nonscalar time-delay systems. It can be applied to time series heavily corrupted by additive and dynamical noise.

  3. Recovery of delay time from time series based on the nearest neighbor method

    Energy Technology Data Exchange (ETDEWEB)

    Prokhorov, M.D., E-mail: mdprokhorov@yandex.ru [Saratov Branch of Kotel' nikov Institute of Radio Engineering and Electronics of Russian Academy of Sciences, Zelyonaya Street, 38, Saratov 410019 (Russian Federation); Ponomarenko, V.I. [Saratov Branch of Kotel' nikov Institute of Radio Engineering and Electronics of Russian Academy of Sciences, Zelyonaya Street, 38, Saratov 410019 (Russian Federation); Department of Nano- and Biomedical Technologies, Saratov State University, Astrakhanskaya Street, 83, Saratov 410012 (Russian Federation); Khorev, V.S. [Department of Nano- and Biomedical Technologies, Saratov State University, Astrakhanskaya Street, 83, Saratov 410012 (Russian Federation)

    2013-12-09

    We propose a method for the recovery of delay time from time series of time-delay systems. The method is based on the nearest neighbor analysis. The method allows one to reconstruct delays in various classes of time-delay systems including systems of high order, systems with several coexisting delays, and nonscalar time-delay systems. It can be applied to time series heavily corrupted by additive and dynamical noise.

  4. Calculating drain delay in high electron mobility transistors

    Science.gov (United States)

    Coffie, R.

    2015-12-01

    An expression for the signal delay (drain delay) associated with electrons traveling through the gate-drain depletion region has been obtained for nonuniform electron velocity. Due to the presence of the gate metal, the signal delay through the gate-drain depletion region was shown to be larger than the signal delay in the base-collector depletion region of a bipolar transistor when equal depletion lengths and velocity profiles were assumed. Drain delay is also shown to be larger in transistors with field plates (independent of field plate connection) compared to transistors without field plates when equal depletion lengths and velocity profiles were assumed. For the case of constant velocity, two expressions for the proportionality constant relating drain delay and electron transit time across the depletion were obtained.

  5. commensurate point delays

    Directory of Open Access Journals (Sweden)

    M. de la Sen

    2005-01-01

    nominal controller is maintained. In the current approach, the finite spectrum assignment is only considered as a particular case of the designer's choice of a (delay-dependent arbitrary spectrum assignment objective.

  6. Quad precision delay generator

    International Nuclear Information System (INIS)

    A Quad Precision Delay Generator delays a digital edge by a programmed amount of time, varying from nanoseconds to microseconds. The output of this generator has an amplitude of the order of tens of volts and rise time of the order of nanoseconds. This was specifically designed and developed to meet the stringent requirements of the plasma focus experiments. Plasma focus is a laboratory device for producing and studying nuclear fusion reactions in hot deuterium plasma. 3 figs

  7. Regional dGEMRIC analysis in patients at risk of osteoarthritis provides additional information about activity related changes in cartilage structure

    DEFF Research Database (Denmark)

    Hawezi, Z K; Lammentausta, E; Svensson, J;

    2016-01-01

    . PURPOSE: To improve the knowledge about exercise effects on cartilage structure by re-analyzing previous images with regional dGEMRIC analysis. MATERIAL AND METHODS: Thirty patients (age range, 38-50 years) with a previous medial meniscus resection were divided into three groups according to self...

  8. The Text of the Agreement of 20 August 1984 Extending the Asian Regional Co-Operative Project on Food Irradiation. Additional acceptance of the Second Extension Agreement

    International Nuclear Information System (INIS)

    A notification of acceptance of the Second Agreement to Extend the Agreement Establishing the Asian Regional Co-operative Project on Food Irradiation by the Governments of Sri Lanka was received by the Agency on 28 October 1985. Pursuant to Article II, paragraph 2, the Second Extension Agreement consequently entered into force on that date with respect to the Government of Sri Lanka

  9. The Text of the Agreement of 20 August 1984 Extending the Asian Regional Co-Operative Project on Food Irradiation. Additional acceptance of the Second Extension Agreement

    International Nuclear Information System (INIS)

    A notification of acceptance of the Second Agreement to Extend the Agreement Establishing the Asian Regional Co-operative Project on Food Irradiation by the Governments of the Philippines was received by the Agency on 25 September 1985. Pursuant to Article II, paragraph 2, the Second Extension Agreement consequently entered into force on that date with respect to the Government of the Philippines

  10. Ral GTPase interacts with the N-terminal in addition to the C-terminal region of PLC-delta1.

    Science.gov (United States)

    Grujic, Ognjen; Bhullar, Rajinder P

    2009-06-12

    Previously, we have shown that RalA, a calmodulin (CaM)-binding protein, binds to the C2 region in the C-terminal of PLC-delta1, and increases its enzymatic activity. Since PLC-delta1 contains a CaM-like region in its N-terminus, we have investigated if RalA can also bind to the N-terminus of PLC-delta1. Therefore, we created a GST-PLC-delta1 construct consisting of the first 294 amino acids of PLC-delta1 (GST-PLC-delta1(1-294)). In vitro binding experiments confirmed that PLC-delta1(1-294) was capable of binding directly to RalA. W-7 coupled to polyacrylamide beads bound pure PLC-delta1, demonstrating that PLC-delta1 contains a CaM-like region. Competition assays with W-7, peptides representing RalA and the newly identified RalB CaM-binding regions, or the IQ peptide from PLC-delta1 were able to inhibit RalA binding to PLC-delta1(1-294). This study demonstrates that there are two binding sites for RalA in PLC-delta1 and provides further insight into the role of Ral GTPase in the regulation of PLC-delta1 function.

  11. A new subfamily of penaeidin with an additional serine-rich region from kuruma shrimp (Marsupenaeus japonicus) contributes to antimicrobial and phagocytic activities.

    Science.gov (United States)

    An, Ming-Yu; Gao, Jie; Zhao, Xiao-Fan; Wang, Jin-Xing

    2016-06-01

    Penaeidins are an important family of antimicrobial peptides (AMPs) in penaeid shrimp. To date, five groups of penaeidins have been identified in penaeid shrimp. All are composed of a proline-rich N-terminus and a C-terminus containing six cysteine residues engaged in three disulfide bridges. In this study, a new type of penaeidin from Marsupenaeus japonicus was identified. The full-length penaeidin contains a unique serine-rich region and a penaeidin domain, which consists of a proline-rich region and a cysteine-rich region. Here, we classify all penaeidins into two subfamilies. All reported penaeidins are in subfamily I, and the new penaeidin identified in M. japonicus is designated as Penaeidin subfamily II (MjPen-II). MjPen-II was expressed in hemocytes, heart, hepatopancreas, gills, stomach and intestine, and was upregulated after bacterial challenge. A liquid bacteriostatic assay showed that MjPen-II had antibacterial activity to some Gram-positive and Gram-negative bacteria. MjPen-II could bind to bacteria by binding to polysaccharides on the surface of bacteria, thus promoting bacterial agglutination. The serine-rich region enhanced the agglutination activity of MjPen-II. The proline-rich domain had a stronger bacterial-binding activity and polysaccharide-binding activity than the cysteine-rich domain. MjPen-II was also found to be involved in the phagocytosis of bacteria and efficiently improved the phagocytosis rate. Therefore, MjPen-II eliminates bacteria through direct bacterial inhibition as well as by promoting phagocytosis in shrimp. PMID:26855016

  12. The Agreement to Extend the Agreement 23 May 1980 Establishing the Asian Regional Co-Operative Project on Food Irradiation. Additional acceptances of the Agreement

    International Nuclear Information System (INIS)

    The Governments of the Philippines and India notified the Agency of their acceptance of the Agreement to Extend the Agreement Establishing the Asian Regional Co-operative Project on Food Irradiation of 8 July 1983, in accordance with Article II, paragraph 1 thereof, on 23 September 1983 and 27 September 1983 respectively. Pursuant to Article II, paragraph 2, the Extension Agreement consequently entered into force with respect to these Governments on the respective dates

  13. Additivity dominance

    Directory of Open Access Journals (Sweden)

    Paul Rozin

    2009-10-01

    Full Text Available Judgments of naturalness of foods tend to be more influenced by the process history of a food, rather than its actual constituents. Two types of processing of a ``natural'' food are to add something or to remove something. We report in this study, based on a large random sample of individuals from six countries (France, Germany, Italy, Switzerland, UK and USA that additives are considered defining features of what makes a food not natural, whereas ``subtractives'' are almost never mentioned. In support of this, skim milk (with major subtraction of fat is rated as more natural than whole milk with a small amount of natural vitamin D added. It is also noted that ``additives'' is a common word, with a synonym reported by a native speaker in 17 of 18 languages, whereas ``subtractive'' is lexicalized in only 1 of the 18 languages. We consider reasons for additivity dominance, relating it to omission bias, feature positive bias, and notions of purity.

  14. Diagrammatic approach to attosecond delays in photoionization

    CERN Document Server

    Dahlström, J M; Lindroth, E

    2012-01-01

    We study laser-assisted photoionization by attosecond pulses using a time-independent formalism based on diagrammatic many-body perturbation theory. Our aim is to provide an ab inito route to the "delays" for this above-threshold ionization process, which is essential for a quantitative understanding of attosecond metrology. We present correction curves for characterization schemes of attosecond pulses, such as "streaking", that account for the delayed atomic response in ionization from neon and argon. We also verify that photoelectron delays from many-electron atoms can be measured using similar schemes if, instead, the so-called continuum--continuum delay is subtracted. Our method is general and it can be extended also to more complex systems and additional correlation effects can be introduced systematically.

  15. Delayed stochastic control

    Science.gov (United States)

    Hosaka, Tadaaki; Ohira, Toru; Lucian, Christian; Milton, John

    2005-03-01

    Time-delayed feedback control becomes problematic in situations in which the time constant of the system is fast compared to the feedback reaction time. In particular, when perturbations are unpredictable, traditional feedback or feed-forward control schemes can be insufficient. Nonethless a human can balance a stick at their fingertip in the presence of fluctuations that occur on time scales shorter than their neural reaction times. Here we study a simple model of a repulsive delayed random walk and demonstrate that the interplay between noise and delay can transiently stabilize an unstable fixed-point. This observation leads to the concept of ``delayed stochastic control,'' i.e. stabilization of tasks, such as stick balancing at the fingertip, by optimally tuning the noise level with respect to the feedback delay time. References:(1)J.L.Cabrera and J.G.Milton, PRL 89 158702 (2002);(2) T. Ohira and J.G.Milton, PRE 52 3277 (1995);(3)T.Hosaka, T.Ohira, C.Lucian, J.L.Cabrera, and J.G.Milton, Prog. Theor. Phys. (to appear).

  16. The WNT2 Gene Polymorphism Associated with Speech Delay Inherent to Autism

    Science.gov (United States)

    Lin, Ping-I; Chien, Yi-Ling; Wu, Yu-Yu; Chen, Chia-Hsiang; Gau, Susan Shur-Fen; Huang, Yu-Shu; Liu, Shih-Kai; Tsai, Wen-Che; Chiu, Yen-Nan

    2012-01-01

    Previous evidence suggests that language function is modulated by genetic variants on chromosome 7q31-36. However, it is unclear whether this region harbors loci that contribute to speech delay in autism. We previously reported that the WNT2 gene located on 7q31 was associated with the risk of autism. Additionally, two other genes on 7q31-36,…

  17. Delayed breast implant reconstruction

    DEFF Research Database (Denmark)

    Hvilsom, Gitte B.; Hölmich, Lisbet R.; Steding-Jessen, Marianne;

    2011-01-01

    Studies of complications following reconstructive surgery with implants among women with breast cancer are needed. As the, to our knowledge, first prospective long-term study we evaluated the occurrence of complications following delayed breast reconstruction separately for one- and two......-stage procedures. From the Danish Registry for Plastic Surgery of the Breast, which has prospectively registered data for women undergoing breast implantations since 1999, we identified 559 women without a history of radiation therapy undergoing 592 delayed breast reconstructions following breast cancer during...... of reoperation was significantly higher following the one-stage procedure. For both procedures, the majority of reoperations were due to asymmetry or displacement of the implant. In conclusion, non-radiated one- and two-stage delayed breast implant reconstructions are associated with substantial risks...

  18. Time Delay Cosmography

    CERN Document Server

    Treu, Tommaso

    2016-01-01

    Gravitational time delays, observed in strong lens systems where the variable background source is multiply-imaged by a massive galaxy in the foreground, provide direct measurements of cosmological distance that are very complementary to other cosmographic probes. The success of the technique depends on the availability and size of a suitable sample of lensed quasars or supernovae, precise measurements of the time delays, accurate modeling of the gravitational potential of the main deflector, and our ability to characterize the distribution of mass along the line of sight to the source. We review the progress made during the last 15 years, during which the first competitive cosmological inferences with time delays were made, and look ahead to the potential of significantly larger lens samples in the near future.

  19. Consideration of QRS complex in addition to ST-segment abnormalities in the estimated "risk region" during acute anterior myocardial infarction

    DEFF Research Database (Denmark)

    van Hellemond, Irene E. G.; Bouwmeester, Sjoerd; Olson, Charles W.;

    2011-01-01

    The myocardial area at risk (MaR) has been estimated in patients with acute myocardial infarction (AMI) by using ST segment-based electrocardiographic (ECG) methods. As the process from ischemia to infarction progresses, the ST-segment deviation is typically replaced by QRS abnormalities causing...... a falsely low estimated total MaR if determined by using ST segment-based methods. The purpose of this study was to investigate if consideration of the abnormalities in the QRS complex, in addition to those in the ST segment, provides a more accurate estimated total MaR during anterior AMI than...

  20. Potlining Additives

    Energy Technology Data Exchange (ETDEWEB)

    Rudolf Keller

    2004-08-10

    In this project, a concept to improve the performance of aluminum production cells by introducing potlining additives was examined and tested. Boron oxide was added to cathode blocks, and titanium was dissolved in the metal pool; this resulted in the formation of titanium diboride and caused the molten aluminum to wet the carbonaceous cathode surface. Such wetting reportedly leads to operational improvements and extended cell life. In addition, boron oxide suppresses cyanide formation. This final report presents and discusses the results of this project. Substantial economic benefits for the practical implementation of the technology are projected, especially for modern cells with graphitized blocks. For example, with an energy savings of about 5% and an increase in pot life from 1500 to 2500 days, a cost savings of $ 0.023 per pound of aluminum produced is projected for a 200 kA pot.

  1. No Time to Delay Life Education in Newly-Established Regional Universities%新建地方本科高校生命教育的迫切性

    Institute of Scientific and Technical Information of China (English)

    赵桂英; 张象林

    2012-01-01

    There are a lot of accidents such as incidental death, suicide, killing and abuse of animals, indicating that the primary education paid little attention to life education, so there is no time to delay life education in universities. The newly-established regional universities take up one third of the total number of u- niversities with students taking up more than a half proportion. Students in those universities tend to be weak in comprehensive quality and academic background, and selfcontemptuous and self-conceited at the same time, so they are easily to go extreme. We have the obligation to enhance life education in those universities. There are many ways we can take, like developing life security and value education, gratitude education, frustration education, death education, mental health education and physical education to improve the young students' living ability and happiness index and cultivate them into all-round practical talents of high-quality%高校学生意外死亡、轻生、杀人、虐待动物等事件时有发生,提示我们基础教育阶段的生命教育效果不佳,提醒我们生命教育刻不容缓。而新建地方本科高校占据了高校总数的三分之一,学生比例超过一半以上,这些学生由于综合素质与文化基础相对较为薄弱,自卑与自大心理并存,对生命价值的认识更易陷入偏颇,因此,在新建地方本科高校必须加强生命教育。新建地方本科高校可以通过多种途径,开展生命安全、生命价值观教育,开展感恩教育、挫折教育、死亡教育,心理健康教育及身体健康训练、健康检测等项活动,从而提升青年学生的生存技能和幸福指数,培养他们成为素质高、发展全面的应用型人才。

  2. Approximation of distributed delays

    CERN Document Server

    Lu, Hao; Eberard, Damien; Simon, Jean-Pierre

    2010-01-01

    We address in this paper the approximation problem of distributed delays. Such elements are convolution operators with kernel having bounded support, and appear in the control of time-delay systems. From the rich literature on this topic, we propose a general methodology to achieve such an approximation. For this, we enclose the approximation problem in the graph topology, and work with the norm defined over the convolution Banach algebra. The class of rational approximates is described, and a constructive approximation is proposed. Analysis in time and frequency domains is provided. This methodology is illustrated on the stabilization control problem, for which simulations results show the effectiveness of the proposed methodology.

  3. Delayed Random Relays

    CERN Document Server

    Ohira, Toru

    2016-01-01

    We present here a system with collection of random walks relaying a signal in one dimension with a presence of a delay. We are interested in the time for a signal to travel from one end (start) to the other end (finish) of the lined group of random walkers. It is found that there is an optimal number of walkers for the signal to travel fastest if the delay is present. We discuss implications of this model and associated behaviors to physical and biological systems.

  4. Dragonflies and damselflies (Insecta: Odonata of the northeastern region of Bangladesh with five new additions to the Odonata fauna of Bangladesh

    Directory of Open Access Journals (Sweden)

    M. Kawsar Khan

    2015-09-01

    Full Text Available Odonata were surveyed in one reserve forest, two national parks, one Eco Park, one lake and one University campus in the northeastern region of Bangladesh from March 2014 to March 2015.  A total of 64 species of Anisoptera and Zygoptera belonging to 41 genera under seven families were recorded.  Among them 45 species and 19 genera were new records for the study area.  Two species of Anisoptera, i.e., Anax indicus Lieftinck, 1942 and Gynacantha khasiaca MacLachlan, 1896, and three species of Zygoptera i.e., Matrona nigripectus Selys, 1879, Agriocnemis kalinga Nair & Subramanian, 2014, and Prodasineura laidlawii Forster, 1907 were recorded for the first time from Bangladesh.  

  5. Delayed traumatic diaphragmatic hernia

    Science.gov (United States)

    Lu, Jing; Wang, Bo; Che, Xiangming; Li, Xuqi; Qiu, Guanglin; He, Shicai; Fan, Lin

    2016-01-01

    Abstract Background: Traumatic diaphragmatic hernias (TDHs) are sometimes difficult to identify at an early stage and can consequently result in diagnostic delays with life-threatening outcomes. It is the aim of this case study to highlight the difficulties encountered with the earlier detection of traumatic diaphragmatic hernias. Methods: Clinical data of patients who received treatment for delayed traumatic diaphragmatic hernias in registers of the First Affiliated Hospital of Xi’an Jiaotong University from 1998 to 2014 were analyzed retrospectively. Results: Six patients were included in this study. Left hemidiaphragm was affected in all of them. Most of the patients had a history of traffic accident and 1 a stab-penetrating injury. The interval from injury to developing symptoms ranged from 2 to 11 years (median 5 years). The hernial contents included the stomach, omentum, small intestine, and colon. Diaphragmatic injury was missed in all of them during the initial managements. All patients received operations once the diagnosis of delayed TDH was confirmed, and no postoperative mortality was detected. Conclusions: Delayed TDHs are not common, but can lead to serious consequences once occurred. Early detection of diaphragmatic injuries is crucial. Surgeons should maintain a high suspicion for injuries of the diaphragm in cases with abdominal or lower chest traumas, especially in the initial surgical explorations. We emphasize the need for radiographical follow-up to detect diaphragmatic injuries at an earlier stage. PMID:27512848

  6. Ignition Delay Studies on Hypergolic Fuel Grains

    Directory of Open Access Journals (Sweden)

    S. R. Jain

    1988-07-01

    Full Text Available The ignition delays of several solid hypergolic fuel compositions, casted using various polymeric binders, or as melts, have been determined with fuming nitric acid as oxidizer. The ignition delays of various hypergolic fuel compositions increase drasticaliy on casting with binders like. carboxyl or hydroxyl termninated polybutadiene. Fuel grains cast using some newly syhthesised epoxy  resins with other ingrcdients, such as curing agent, magnesium powder and fuel, have short ignition delays of the order of 200 ms, and also good mechanical strength. Increasing the amount of binder in the composition retards the hypergolicity of the rain. Similar studies have been made on melt-cast systems using low melting hypergolic fuels for casting fuel powders. The ignition delays of the melt-cast grains, are longer than those determined taking the composition in the powder form. The effect of highly hypergolic additives, and metal powders, on the ignition delay of the cast compositions has been determined. Grains having good mechanical strength and short ignition delays have been obtained by optimising the fuel grain composition.

  7. Stability analysis of a class of fractional delay differential equations

    Indian Academy of Sciences (India)

    Sachin B Bhalekar

    2013-08-01

    In this paper we analyse stability of nonlinear fractional order delay differential equations of the form $D^{} y(t) = af(y(t - )) - {\\text{by}} (t)$, where $D^{}$ is a Caputo fractional derivative of order 0 < ≤ 1. We describe stability regions using critical curves. To explain the proposed theory, we discuss fractional order logistic equation with delay.

  8. Cross delay line sensor characterization

    Energy Technology Data Exchange (ETDEWEB)

    Owens, Israel J [Los Alamos National Laboratory; Remelius, Dennis K [Los Alamos National Laboratory; Tiee, Joe J [Los Alamos National Laboratory; Buck, Steven E [Los Alamos National Laboratory; Whittemore, Stephen R [Los Alamos National Laboratory; Thompson, David C [Los Alamos National Laboratory; Shirey, Robert [Los Alamos National Laboratory

    2010-01-01

    There exists a wealth of information in the scientific literature on the physical properties and device characterization procedures for complementary metal oxide semiconductor (CMOS), charge coupled device (CCD) and avalanche photodiode (APD) format detectors. Numerous papers and books have also treated photocathode operation in the context of photomultiplier tube (PMT) operation for either non imaging applications or limited night vision capability. However, much less information has been reported in the literature about the characterization procedures and properties of photocathode detectors with novel cross delay line (XDL) anode structures. These allow one to detect single photons and create images by recording space and time coordinate (X, Y & T) information. In this paper, we report on the physical characteristics and performance of a cross delay line anode sensor with an enhanced near infrared wavelength response photocathode and high dynamic range micro channel plate (MCP) gain (> 10{sup 6}) multiplier stage. Measurement procedures and results including the device dark event rate (DER), pulse height distribution, quantum and electronic device efficiency (QE & DQE) and spatial resolution per effective pixel region in a 25 mm sensor array are presented. The overall knowledge and information obtained from XDL sensor characterization allow us to optimize device performance and assess capability. These device performance properties and capabilities make XDL detectors ideal for remote sensing field applications that require single photon detection, imaging, sub nano-second timing response, high spatial resolution (10's of microns) and large effective image format.

  9. Consideration of QRS complex in addition to ST-segment abnormalities in the estimation of the "risk region" during acute anterior or inferior myocardial infarction.

    Science.gov (United States)

    Vervaat, F E; Bouwmeester, S; van Hellemond, I E G; Wagner, G S; Gorgels, A P M

    2014-01-01

    The myocardial area at risk (MaR) is an important aspect in acute ST-elevation myocardial infarction (STEMI). It represents the myocardium at the onset of the STEMI that is ischemic and could become infarcted if no reperfusion occurs. The MaR, therefore, has clinical value because it gives an indication of the amount of myocardium that could potentially be salvaged by rapid reperfusion therapy. The most validated method for measuring the MaR is (99m)Tc-sestamibi SPECT, but this technique is not easily applied in the clinical setting. Another method that can be used for measuring the MaR is the standard ECG-based scoring system, Aldrich ST score, which is more easily applied. This ECG-based scoring system can be used to estimate the extent of acute ischemia for anterior or inferior left ventricular locations, by considering quantitative changes in the ST-segment. Deviations in the ST-segment baseline that occur following an acute coronary occlusion represent the ischemic changes in the transmurally ischemic myocardium. In most instances however, the ECG is not available at the very first moments of STEMI and as times passes the ischemic myocardium becomes necrotic with regression of the ST-segment deviation along with progressive changes of the QRS complex. Thus over the time course of the acute event, the Aldrich ST score would be expected to progressively underestimate the MaR, as was seen in studies with SPECT as gold standard; anterior STEMI (r=0.21, p=0.32) and inferior STEMI (r=0.17, p=0.36). Another standard ECG-based scoring system is the Selvester QRS score, which can be used to estimate the final infarct size by considering the quantitative changes in the QRS complex. Therefore, additional consideration of the Selvester QRS score in the acute phase could potentially provide the "component" of infarcted myocardium that is missing when the Aldrich ST score alone is used to determine the MaR in the acute phase, as was seen in studies with SPECT as gold

  10. Whole heart coronary imaging with flexible acquisition window and trigger delay.

    Directory of Open Access Journals (Sweden)

    Keigo Kawaji

    Full Text Available Coronary magnetic resonance imaging (MRI requires a correctly timed trigger delay derived from a scout cine scan to synchronize k-space acquisition with the quiescent period of the cardiac cycle. However, heart rate changes between breath-held cine and free-breathing coronary imaging may result in inaccurate timing errors. Additionally, the determined trigger delay may not reflect the period of minimal motion for both left and right coronary arteries or different segments. In this work, we present a whole-heart coronary imaging approach that allows flexible selection of the trigger delay timings by performing k-space sampling over an enlarged acquisition window. Our approach addresses coronary motion in an interactive manner by allowing the operator to determine the temporal window with minimal cardiac motion for each artery region. An electrocardiogram-gated, k-space segmented 3D radial stack-of-stars sequence that employs a custom rotation angle is developed. An interactive reconstruction and visualization platform is then employed to determine the subset of the enlarged acquisition window for minimal coronary motion. Coronary MRI was acquired on eight healthy subjects (5 male, mean age = 37 ± 18 years, where an enlarged acquisition window of 166-220 ms was set 50 ms prior to the scout-derived trigger delay. Coronary visualization and sharpness scores were compared between the standard 120 ms window set at the trigger delay, and those reconstructed using a manually adjusted window. The proposed method using manual adjustment was able to recover delineation of five mid and distal right coronary artery regions that were otherwise not visible from the standard window, and the sharpness scores improved in all coronary regions using the proposed method. This paper demonstrates the feasibility of a whole-heart coronary imaging approach that allows interactive selection of any subset of the enlarged acquisition window for a tailored reconstruction

  11. Refinement of the Region for Split Hand/Foot Malformation 5 on 2q31.1

    OpenAIRE

    Theisen, A.; Rosenfeld, J.A.; Shane, K.; McBride, K.L.; Atkin, J F; Gaba, C.; Hoo, J.; Kurczynski, T W; Schnur, R. E.; Coffey, L.B.; Zackai, E H; Schimmenti, L.; Friedman, N.; Zabukovec, M.; Ball, S

    2011-01-01

    Background: Deletions that encompass 2q31.1 have been proposed as a microdeletion syndrome with common clinical features, including intellectual disability/developmental delay, microcephaly, cleft palate, growth delay, and hand/foot anomalies. In addition, several genes within this region have been proposed as candidates for split hand-foot malformation 5 (SHFM5). Methods: To delineate the genotype-phenotype correlation between deletions of this region, we identified 14 individuals with delet...

  12. Calibration of Low-Frequency, Wide-Field Radio Interferometers Using Delay/Delay-Rate Filtering

    CERN Document Server

    Parsons, Aaron R

    2009-01-01

    We present a filtering technique that can be applied to individual baselines of wide-bandwidth, wide-field interferometric data to geometrically select regions on the celestial sphere that contain primary calibration sources. The technique relies on the Fourier transformation of wide-band frequency spectra from a given baseline to obtain one-dimensional "delay images", and then the transformation of a time-series of delay images to obtain two-dimensional "delay/delay-rate images." Source selection is possible in these images given appropriate combinations of baseline, bandwidth, integration time and source location. Strong and persistent radio frequency interference (RFI) limits the effectiveness of this source selection owing to the removal of data by RFI excision algorithms. A one-dimensional, complex CLEAN algorithm has been developed to compensate for RFI-excision effects. This approach allows CLEANed, source-isolated data to be used to isolate bandpass and primary beam gain functions. These techniques ar...

  13. Stability domains of the delay and PID coefficients for general time-delay systems

    Science.gov (United States)

    Almodaresi, Elham; Bozorg, Mohammad; Taghirad, Hamid D.

    2016-04-01

    Time delays are encountered in many physical systems, and they usually threaten the stability and performance of closed-loop systems. The problem of determining all stabilising proportional-integral-derivative (PID) controllers for systems with perturbed delays is less investigated in the literature. In this study, the Rekasius substitution is employed to transform the system parameters to a new space. Then, the singular frequency (SF) method is revised for the Rekasius transformed system. A novel technique is presented to compute the ranges of time delay for which stable PID controller exists. This stability range cannot be readily computed from the previous methods. Finally, it is shown that similar to the original SF method, finite numbers of singular frequencies are sufficient to compute the stable regions in the space of time delay and controller coefficients.

  14. Time-Delay Interferometry

    Science.gov (United States)

    Dhurandhar, Sanjeev V.; Tinto, Massimo

    2005-07-01

    Equal-arm interferometric detectors of gravitational radiation allow phase measurements many orders of magnitude below the intrinsic phase stability of the laser injecting light into their arms. This is because the noise in the laser light is common to both arms, experiencing exactly the same delay, and thus cancels when it is differenced at the photo detector. In this situation, much lower level secondary noises then set the overall performance. If, however, the two arms have different lengths (as will necessarily be the case with space-borne interferometers), the laser noise experiences different delays in the two arms and will hence not directly cancel at the detector. In order to solve this problem, a technique involving heterodyne interferometry with unequal arm lengths and independent phase-difference readouts has been proposed. It relies on properly time-shifting and linearly combining independent Doppler measurements, and for this reason it has been called Time-Delay Interferometry (TDI). This article provides an overview of the theory and mathematical foundations of TDI as it will be implemented by the forthcoming space-based interferometers such as the Laser Interferometer Space Antenna (LISA) mission. We have purposely left out from this first version of our "Living Review" article on TDI all the results of more practical and experimental nature, as well as all the aspects of TDI that the data analysts will need to account for when analyzing the LISA TDI data combinations. Our forthcoming "second edition" of this review paper will include these topics.

  15. Time-Delay Interferometry

    Directory of Open Access Journals (Sweden)

    Massimo Tinto

    2014-08-01

    Full Text Available Equal-arm detectors of gravitational radiation allow phase measurements many orders of magnitude below the intrinsic phase stability of the laser injecting light into their arms. This is because the noise in the laser light is common to both arms, experiencing exactly the same delay, and thus cancels when it is differenced at the photo detector. In this situation, much lower level secondary noises then set the overall performance. If, however, the two arms have different lengths (as will necessarily be the case with space-borne interferometers, the laser noise experiences different delays in the two arms and will hence not directly cancel at the detector. In order to solve this problem, a technique involving heterodyne interferometry with unequal arm lengths and independent phase-difference readouts has been proposed. It relies on properly time-shifting and linearly combining independent Doppler measurements, and for this reason it has been called time-delay interferometry (TDI. This article provides an overview of the theory, mathematical foundations, and experimental aspects associated with the implementation of TDI. Although emphasis on the application of TDI to the Laser Interferometer Space Antenna (LISA mission appears throughout this article, TDI can be incorporated into the design of any future space-based mission aiming to search for gravitational waves via interferometric measurements. We have purposely left out all theoretical aspects that data analysts will need to account for when analyzing the TDI data combinations.

  16. [Acromegaly: reducing diagnostic delay].

    Science.gov (United States)

    Giustina, Andrea

    2016-08-01

    Diagnostic delay of acromegaly is still very relevant (6-8 years on average) without substantial changes in last twenty years. Clinical impact of this diagnostic delay is significant: tumor growth (2/3 of the patients at diagnosis bear a pituitary macroadenoma), development of irreversible complications (arthropathy, sleep apnea) and in all increased mortality. Reasons for this delay are related to the disease itself (facial and acral changes are very slow and subtle) but also to medical unawareness. Simple tools based on a few sufficiently sensitive and specific signs and symptoms which can trigger the diagnostic suspect would be useful in clinical practice. Global evaluation during follow-up (tumor volume, signs and symptoms, complications, circulating levels of growth hormone and its peripheral mediator IGF-I) has become crucial for the therapeutic decision making. In this regard, tools like SAGIT are now under validation and are expected to improve management of acromegaly. In fact, in the last 30 years there has been a relevant growth of the medical options to treat acromegaly and in the near future there will be an expansion of the medical options. This will greatly help the needed personalization of treatment which necessarily should consider patient convenience and preference and control of complications such as diabetes mellitus. PMID:27571562

  17. $\\beta$-delayed proton decays near the proton drip line

    CERN Document Server

    Xu, S W; Huang, W X; Li, Z K; Pan Qiang Yan; Shu, N C; Wang, K; Wang, X D; Xie, Y X; Xing, Y B; Xu, F R; Yu, Y; 10.1103/PhysRevC.71.054318

    2005-01-01

    We briefly reviewed and summarized the experimental study on beta - delayed proton decays published by our group over the last 8 years, namely the experimental observation of beta -delayed proton decays of nine new nuclides in the rare-earth region near the proton drip line and five nuclides in the mass 90 region with N approximately=Z by utilizing the p- gamma coincidence technique in combination with a He-jet tape transport system. In addition, important technical details of the experiments were provided. The experimental results were compared to the theoretical predictions of some nuclear models, resulting in the following conclusions. (1) The experimental half- lives for /sup 85/Mo, /sup 92/Rh, as well as the predicted "waiting point" nuclei /sup 89/Ru and /sup 93/Pd were 5-10 times longer than the macroscopic-microscopic model predictions of Moller et al. At. Data Nucl. Data Tables 66,131(1997). These data considerably influenced the predictions of the mass abundances of the nuclides produced in the rp p...

  18. Numerical Investigation of Noise Enhanced Stability Phenomenon in a Time-Delayed Metastable System

    Institute of Scientific and Technical Information of China (English)

    JIA Zheng-Lin

    2008-01-01

    @@ The transient properties of a time-delayed metastable system subjected to the additive white noise are investigated by means of the stochastic simulation method. The noise enhanced stability phenomenon (NES) can be observed in this system and the effect of the delay time on the NES shows a critical behaviour, i.e., there is a critical value of the delay time Tc ≈ 1, above which the time delay enhances the NES effect with the delay time increasing and below which the time delay weakens the NES effect as the delay time increases.

  19. Stimulus-dependent synchronization in delayed-coupled neuronal networks

    Science.gov (United States)

    Esfahani, Zahra G.; Gollo, Leonardo L.; Valizadeh, Alireza

    2016-01-01

    Time delay is a general feature of all interactions. Although the effects of delayed interaction are often neglected when the intrinsic dynamics is much slower than the coupling delay, they can be crucial otherwise. We show that delayed coupled neuronal networks support transitions between synchronous and asynchronous states when the level of input to the network changes. The level of input determines the oscillation period of neurons and hence whether time-delayed connections are synchronizing or desynchronizing. We find that synchronizing connections lead to synchronous dynamics, whereas desynchronizing connections lead to out-of-phase oscillations in network motifs and to frustrated states with asynchronous dynamics in large networks. Since the impact of a neuronal network to downstream neurons increases when spikes are synchronous, networks with delayed connections can serve as gatekeeper layers mediating the firing transfer to other regions. This mechanism can regulate the opening and closing of communicating channels between cortical layers on demand. PMID:27001428

  20. Stimulus-dependent synchronization in delayed-coupled neuronal networks.

    Science.gov (United States)

    Esfahani, Zahra G; Gollo, Leonardo L; Valizadeh, Alireza

    2016-03-22

    Time delay is a general feature of all interactions. Although the effects of delayed interaction are often neglected when the intrinsic dynamics is much slower than the coupling delay, they can be crucial otherwise. We show that delayed coupled neuronal networks support transitions between synchronous and asynchronous states when the level of input to the network changes. The level of input determines the oscillation period of neurons and hence whether time-delayed connections are synchronizing or desynchronizing. We find that synchronizing connections lead to synchronous dynamics, whereas desynchronizing connections lead to out-of-phase oscillations in network motifs and to frustrated states with asynchronous dynamics in large networks. Since the impact of a neuronal network to downstream neurons increases when spikes are synchronous, networks with delayed connections can serve as gatekeeper layers mediating the firing transfer to other regions. This mechanism can regulate the opening and closing of communicating channels between cortical layers on demand.

  1. Impulsivity Relates To Striatal Gray Matter Volumes In Humans: Evidence From A Delay Discounting Paradigm

    Directory of Open Access Journals (Sweden)

    Melanie eTschernegg

    2015-07-01

    Full Text Available Time-stable personality traits, such as impulsivity and its relationship with functional and structural brain alterations, have gained much attention in the recent literature. Evidence from functional neuroimaging data implies an association between impulsivity and cortical as well as subcortical areas of the reward system. Discounting future rewards during impulsive decisions can be related to activation in the orbitofrontal cortex and striatum. Cortical structural changes in prefrontal regions have been found for introspective impulsivity measures. The present study focuses on brain regions associated with delay discounting to investigate structural manifestations of trait impulsivity. To test this, seventy subjects underwent structural MRI followed by a behavioural delay discounting task outside of the scanner to measure impulsivity with questions like: Would you like to have 3 € immediately or 10 € in five days?. The amount of smaller-but-sooner decisions was calculated and used as a measure of behavioural impulsivity. Furthermore, we estimated subject’s individual delay discounting parameter K reflecting the tendency to discount future rewards. Behaviourally, we found strong evidence in favour of a discounting utility model compared to a standard hyperbolic model of choice valuation. Neuronally, we focused on cortical and subcortical brain structure and investigated the association of behavioural impulsivity with delay discounting tendencies and gray matter volume. Voxel-based morphometric analyses showed positive correlations between delay discounting and gray matter volume in the striatum. Additional analyses using Freesurfer provided evidence for a positive correlation between delay discounting and gray matter volume of the caudate. Taken together, our study provides strong evidence for a structural manifestation of time-stable trait impulsivity in the human brain.

  2. The Cost of Delaying Approval of Golden Rice

    OpenAIRE

    Wesseler, J.H.H.; Kaplan, S; Zilberman, D.

    2014-01-01

    More than 250,000 children go blind every year because of Vitamin A deficiency. Vitamin A intake can be enhanced by consuming Golden Rice—a genetically engineered variety of rice. It was available for commercialization in 2002, but approval has been delayed. We estimate that this delay has resulted in 600,000 to 1.2 million additional cases of blindness.

  3. Synchronization Stability in Weighted Complex Networks with Coupling Delays

    Institute of Scientific and Technical Information of China (English)

    WANG Qing-Yun; DUAN Zhi-Sheng; CHEN Guan-Rong; LU Qi-Shao

    2009-01-01

    Realistic networks display not only a complex topological structure, but also a heterogeneous distribution of weights in connection strengths.In addition, the information spreading through a complex network is often associated with time delays due to the finite speed of signal transmission over a distance.Hence, the weighted complex network with coupling delays have meaningful implications in real world, and resultantly ga/ns increasing attention in various fields of science and engineering.Based on the theory of asymptotic stability of linear time-delay systems, synchronization stability of the weighted complex dynamical network with coupling delays is investigated, and simple criteria are obtained for both delay-independent and delay-dependent stabilities of synchronization states.The obtained criteria in this paper encompass the established results in the literature as special cases.Some examples are given to illustrate the theoretical results.

  4. Delayed Macular Hole Closure

    Directory of Open Access Journals (Sweden)

    Peter Distelmaier

    2014-04-01

    Full Text Available Purpose: The presented case raises questions regarding the favorable scheduling of planned postoperative care and the ideal observation interval to decide for reoperations in macular hole surgery. Furthermore a discussion about the use of short- and long-acting gas tamponades in macular hole surgery is encouraged. Methods: We present an interventional case report and a short review of the pertinent literature. Results: We report a case of spontaneous delayed macular hole closure after vitreoretinal surgery had been performed initially without the expected success. A 73-year-old male Caucasian patient presented at our clinic with a stage 2 macular hole in his left eye. He underwent 23-gauge pars plana vitrectomy and internal limiting membrane peeling with a 20% C2F6-gas tamponade. Sixteen days after the procedure, an OCT scan revealed a persistent stage 2 macular hole, and the patient was scheduled for reoperation. Surprisingly, at the date of planned surgery, which was another 11 days later, the macular hole had resolved spontaneously without any further intervention. Conclusions: So far no common opinion exists regarding the use of short- or long-acting gas in macular hole surgery. Our case of delayed macular hole closure after complete resorption of the gas tamponade raises questions about the need and duration of strict prone positioning after surgery. Furthermore short-acting gas might be as efficient as long-acting gas. We suggest to wait with a second intervention at least 4 weeks after the initial surgery, since a delayed macular hole closure is possible.

  5. Vehicle barrier with access delay

    Science.gov (United States)

    Swahlan, David J; Wilke, Jason

    2013-09-03

    An access delay vehicle barrier for stopping unauthorized entry into secure areas by a vehicle ramming attack includes access delay features for preventing and/or delaying an adversary from defeating or compromising the barrier. A horizontally deployed barrier member can include an exterior steel casing, an interior steel reinforcing member and access delay members disposed within the casing and between the casing and the interior reinforcing member. Access delay members can include wooden structural lumber, concrete and/or polymeric members that in combination with the exterior casing and interior reinforcing member act cooperatively to impair an adversarial attach by thermal, mechanical and/or explosive tools.

  6. Delayed breast implant reconstruction

    DEFF Research Database (Denmark)

    Hvilsom, Gitte B.; Hölmich, Lisbet R.; Steding-Jessen, Marianne;

    2012-01-01

    We evaluated the association between radiation therapy and severe capsular contracture or reoperation after 717 delayed breast implant reconstruction procedures (288 1- and 429 2-stage procedures) identified in the prospective database of the Danish Registry for Plastic Surgery of the Breast during...... of radiation therapy was associated with a non-significantly increased risk of reoperation after both 1-stage (HR = 1.4; 95% CI: 0.7-2.5) and 2-stage (HR = 1.6; 95% CI: 0.9-3.1) procedures. Reconstruction failure was highest (13.2%) in the 2-stage procedures with a history of radiation therapy. Breast...

  7. Stability and delay sensitivity of neutral fractional-delay systems.

    Science.gov (United States)

    Xu, Qi; Shi, Min; Wang, Zaihua

    2016-08-01

    This paper generalizes the stability test method via integral estimation for integer-order neutral time-delay systems to neutral fractional-delay systems. The key step in stability test is the calculation of the number of unstable characteristic roots that is described by a definite integral over an interval from zero to a sufficient large upper limit. Algorithms for correctly estimating the upper limits of the integral are given in two concise ways, parameter dependent or independent. A special feature of the proposed method is that it judges the stability of fractional-delay systems simply by using rough integral estimation. Meanwhile, the paper shows that for some neutral fractional-delay systems, the stability is extremely sensitive to the change of time delays. Examples are given for demonstrating the proposed method as well as the delay sensitivity. PMID:27586618

  8. Stability and delay sensitivity of neutral fractional-delay systems

    Science.gov (United States)

    Xu, Qi; Shi, Min; Wang, Zaihua

    2016-08-01

    This paper generalizes the stability test method via integral estimation for integer-order neutral time-delay systems to neutral fractional-delay systems. The key step in stability test is the calculation of the number of unstable characteristic roots that is described by a definite integral over an interval from zero to a sufficient large upper limit. Algorithms for correctly estimating the upper limits of the integral are given in two concise ways, parameter dependent or independent. A special feature of the proposed method is that it judges the stability of fractional-delay systems simply by using rough integral estimation. Meanwhile, the paper shows that for some neutral fractional-delay systems, the stability is extremely sensitive to the change of time delays. Examples are given for demonstrating the proposed method as well as the delay sensitivity.

  9. Benefit achieved through determination of patient-specific, best scan delay after administration of contrast agent in cardiovascular CT examination

    International Nuclear Information System (INIS)

    A peripheral contrast bolus was administered intravenously in 138 consecutive patients to determine the time to maximum density in a left ventricular or aortic region of interest by electron beam CT. 20 EKG-triggered scans were acquired within 70 heartbeats. The deviation of the time to maximum density from a standard, fixed scan delay was determined. Results: Mean time to maximum density was 22 s, and the average deviation from that mean was 5 s. At an injection rate of 4 cc/s, this deviation implies that determining the individual scan delay from a test bolus injection may potentially save 20 cc contrast per patient. This amount of contrast agent, in turn, is required for the test bolus. Conclusion: Deriving the individual scan delay from test bolus kinetics may improve image contrast in cardiovascular CT studies without additional contrast expense. (orig.)

  10. Location Estimation using Delayed Measurements

    DEFF Research Database (Denmark)

    Bak, Martin; Larsen, Thomas Dall; Nørgård, Peter Magnus;

    1998-01-01

    When combining data from various sensors it is vital to acknowledge possible measurement delays. Furthermore, the sensor fusion algorithm, often a Kalman filter, should be modified in order to handle the delay. The paper examines different possibilities for handling delays and applies a new techn...... technique to a sensor fusion system for estimating the location of an autonomous guided vehicle. The system fuses encoder and vision measurements in an extended Kalman filter. Results from experiments in a real environment are reported...

  11. Modeling delay in genetic networks: From delay birth-death processes to delay stochastic differential equations

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Chinmaya; López, José Manuel; Azencott, Robert; Ott, William [Department of Mathematics, University of Houston, Houston, Texas 77004 (United States); Bennett, Matthew R. [Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77204, USA and Institute of Biosciences and Bioengineering, Rice University, Houston, Texas 77005 (United States); Josić, Krešimir [Department of Mathematics, University of Houston, Houston, Texas 77004 (United States); Department of Biology and Biochemistry, University of Houston, Houston, Texas 77204 (United States)

    2014-05-28

    Delay is an important and ubiquitous aspect of many biochemical processes. For example, delay plays a central role in the dynamics of genetic regulatory networks as it stems from the sequential assembly of first mRNA and then protein. Genetic regulatory networks are therefore frequently modeled as stochastic birth-death processes with delay. Here, we examine the relationship between delay birth-death processes and their appropriate approximating delay chemical Langevin equations. We prove a quantitative bound on the error between the pathwise realizations of these two processes. Our results hold for both fixed delay and distributed delay. Simulations demonstrate that the delay chemical Langevin approximation is accurate even at moderate system sizes. It captures dynamical features such as the oscillatory behavior in negative feedback circuits, cross-correlations between nodes in a network, and spatial and temporal information in two commonly studied motifs of metastability in biochemical systems. Overall, these results provide a foundation for using delay stochastic differential equations to approximate the dynamics of birth-death processes with delay.

  12. Architectural Overview of Delay Tolerant Network.

    OpenAIRE

    S.Fowjiya; A.Udhayachandrika; Dr.A.Kathirvel

    2013-01-01

    This paper discuss about the current design of the Delay/Disruption Tolerant Networking (DTN) Architecture and also deals with some open issues regarding the architecture. At present we had achieved some stability within the design, but somehow additional experience is required to understand the concept of long ongoing transmissions at long running operational environments as well as to know the architectural complexity.The parameters including congestion, routing scenarios, security, and tra...

  13. Management of delayed nuclear power plant projects

    International Nuclear Information System (INIS)

    According to the available information at the IAEA PRIS (Power Reactor Information System) at the end of 1998 there were more than 40 nuclear power plant projects with delays of five or more years with respect to the originally scheduled commercial operation. The degree of conformance with original construction schedules showed large variations due to several issues, including financial, economic and public opinion factors. Taking into account the number of projects with several years delay in their original schedules, it was considered useful to identify the subject areas where exchange of experience among Member States would be mutually beneficial in identification of problems and development of guidance for successful management of the completion of these delayed projects. A joint programme of the IAEA Departments of Nuclear Energy (Nuclear Power Engineering Section) and Technical Co-operation (Europe Section, with additional support from the Latin America and West Asia Sections) was set up during the period 1997-1998. The specific aim of the programme was to provide assistance in the management of delayed nuclear power plants regarding measures to maintain readiness for resuming the project implementation schedule when the conditions permit. The integration of IAEA interdepartmental resources enabled the participation of 53 experts from 14 Member States resulting in a wider exchange of experience and dissemination of guidance. Under the framework of the joint programme, senior managers directly responsible for delayed nuclear power plant projects identified several issues or problem areas that needed to be addressed and guidance on management be provided. A work plan for the development of several working documents, addressing the different issues, was established. Subsequently these documents were merged into a single one to produce the present publication. This publication provides information and practical examples on necessary management actions to preserve

  14. Improving Accuracy in Arrhenius Models of Cell Death: Adding a Temperature-Dependent Time Delay.

    Science.gov (United States)

    Pearce, John A

    2015-12-01

    The Arrhenius formulation for single-step irreversible unimolecular reactions has been used for many decades to describe the thermal damage and cell death processes. Arrhenius predictions are acceptably accurate for structural proteins, for some cell death assays, and for cell death at higher temperatures in most cell lines, above about 55 °C. However, in many cases--and particularly at hyperthermic temperatures, between about 43 and 55 °C--the particular intrinsic cell death or damage process under study exhibits a significant "shoulder" region that constant-rate Arrhenius models are unable to represent with acceptable accuracy. The primary limitation is that Arrhenius calculations always overestimate the cell death fraction, which leads to severely overoptimistic predictions of heating effectiveness in tumor treatment. Several more sophisticated mathematical model approaches have been suggested and show much-improved performance. But simpler models that have adequate accuracy would provide useful and practical alternatives to intricate biochemical analyses. Typical transient intrinsic cell death processes at hyperthermic temperatures consist of a slowly developing shoulder region followed by an essentially constant-rate region. The shoulder regions have been demonstrated to arise chiefly from complex functional protein signaling cascades that generate delays in the onset of the constant-rate region, but may involve heat shock protein activity as well. This paper shows that acceptably accurate and much-improved predictions in the simpler Arrhenius models can be obtained by adding a temperature-dependent time delay. Kinetic coefficients and the appropriate time delay are obtained from the constant-rate regions of the measured survival curves. The resulting predictions are seen to provide acceptably accurate results while not overestimating cell death. The method can be relatively easily incorporated into numerical models. Additionally, evidence is presented

  15. On modeling the digital gate delay under process variation

    Institute of Scientific and Technical Information of China (English)

    Gao Mingzhi; Ye Zuochang; Wang Yan; Yu Zhiping

    2011-01-01

    To achieve a characterization method for the gate delay library used in block based statistical static timing analysis with neither unacceptably poor accuracy nor forbiddingly high cost,we found that general-purpose gate delay models are useful as intermediaries between the circuit simulation data and the gate delay models in required forms.In this work,two gate delay models for process variation considering different driving and loading conditions are proposed.From the testing results,these two models,especially the one that combines effective dimension reduction (EDR) from statistics society with comprehensive gate delay models,offer good accuracy with low characterization cost,and they are thus competent for use in statistical timing analysis (SSTA).In addition,these two models have their own value in other SSTA techniques.

  16. Chaos synchronization by resonance of multiple delay times

    Science.gov (United States)

    Martin, Manuel Jimenez; D'Huys, Otti; Lauerbach, Laura; Korutcheva, Elka; Kinzel, Wolfgang

    2016-02-01

    Chaos synchronization may arise in networks of nonlinear units with delayed couplings. We study complete and sublattice synchronization generated by resonance of two large time delays with a specific ratio. As it is known for single-delay networks, the number of synchronized sublattices is determined by the greatest common divisor (GCD) of the network loop lengths. We demonstrate analytically the GCD condition in networks of iterated Bernoulli maps with multiple delay times and complement our analytic results by numerical phase diagrams, providing parameter regions showing complete and sublattice synchronization by resonance for Tent and Bernoulli maps. We compare networks with the same GCD with single and multiple delays, and we investigate the sensitivity of the correlation to a detuning between the delays in a network of coupled Stuart-Landau oscillators. Moreover, the GCD condition also allows detection of time-delay resonances, leading to high correlations in nonsynchronizable networks. Specifically, GCD-induced resonances are observed both in a chaotic asymmetric network and in doubly connected rings of delay-coupled noisy linear oscillators.

  17. Delay Adjusted Incidence Infographic

    Science.gov (United States)

    This Infographic shows the National Cancer Institute SEER Incidence Trends. The graphs show the Average Annual Percent Change (AAPC) 2002-2011. For Men, Thyroid: 5.3*,Liver & IBD: 3.6*, Melanoma: 2.3*, Kidney: 2.0*, Myeloma: 1.9*, Pancreas: 1.2*, Leukemia: 0.9*, Oral Cavity: 0.5, Non-Hodgkin Lymphoma: 0.3*, Esophagus: -0.1, Brain & ONS: -0.2*, Bladder: -0.6*, All Sites: -1.1*, Stomach: -1.7*, Larynx: -1.9*, Prostate: -2.1*, Lung & Bronchus: -2.4*, and Colon & Rectum: -3/0*. For Women, Thyroid: 5.8*, Liver & IBD: 2.9*, Myeloma: 1.8*, Kidney: 1.6*, Melanoma: 1.5, Corpus & Uterus: 1.3*, Pancreas: 1.1*, Leukemia: 0.6*, Brain & ONS: 0, Non-Hodgkin Lymphoma: -0.1, All Sites: -0.1, Breast: -0.3, Stomach: -0.7*, Oral Cavity: -0.7*, Bladder: -0.9*, Ovary: -0.9*, Lung & Bronchus: -1.0*, Cervix: -2.4*, and Colon & Rectum: -2.7*. * AAPC is significantly different from zero (p<.05). Rates were adjusted for reporting delay in the registry. www.cancer.gov Source: Special section of the Annual Report to the Nation on the Status of Cancer, 1975-2011.

  18. Delayed unlatching mechanism

    Energy Technology Data Exchange (ETDEWEB)

    Bzorgi, Fariborz M.

    2015-05-19

    In various embodiments an apparatus is presented for securing a structure such as a door, window, hatch, or gate that moves between an open and a closed position relative to a fixed structure to provide or deny access to a compartment, a room, an outdoor area, or a facility. Various embodiments provide a delay in opening the closure of sufficient duration to frustrate a rapid activation that might be desired by a person who is attempting to pass through the closure for some illicit purpose. Typically, hydraulics are used to activate the apparatus and no electrical energy or electronic signals are employed. In one embodiment, a plurality of actuations of a hand lever operates a hydraulic pump that moves a locking bolt from a first position in which a locking bolt is engaged with a recess in the fixed structure (preventing opening of a gate) to a second position in which the locking bolt is disengaged from the recess to permit opening of the gate.

  19. #FakeNobelDelayReasons

    CERN Multimedia

    2013-01-01

    Tuesday’s hour-long delay of the Nobel Prize in Physics announcement was (and still is) quite the cause for speculation. But on the Twittersphere, it was simply the catalyst for some fantastic puns, so-bad-they're-good physics jokes and other shenanigans. Here are some of our favourite #FakeNobelDelayReasons.    

  20. Delayed Reinforcement of Operant Behavior

    Science.gov (United States)

    Lattal, Kennon A.

    2010-01-01

    The experimental analysis of delay of reinforcement is considered from the perspective of three questions that seem basic not only to understanding delay of reinforcement but also, by implication, the contributions of temporal relations between events to operant behavior. The first question is whether effects of the temporal relation between…

  1. Consumer Procrastination and Purchase Delay

    OpenAIRE

    Darpy, Denis

    2000-01-01

    Recent research on purchase delay have developed numerous situational and individual causes. This paper proposes Consumer Procrastination to conceptualize the individual factor which influence people to chronically delay their purchases. Consumer Procrastination is measured with a new scale. An experiment is designed to show the importance of its impact on the decision to not choose along with context effects.

  2. Magnetic bearing optical delay line

    NARCIS (Netherlands)

    Dool, T.C. van den; Kamphues, F.G.; Fouss, B.; Henrioulle, K.; Hogenhuis, H.

    2004-01-01

    TNO TPD, in close cooperation with Micromega-Dynamics and Dutch Space, has developed an advanced Optical Delay Line (ODL) for use in PRIMA, GENIE and other ground based interferometers. The delay line design is modular and flexible, which makes scaling for other applications a relatively easy task.

  3. Carbon monoxide-induced delayed amnesia, delayed neuronal death and change in acetylcholine concentration in mice

    Energy Technology Data Exchange (ETDEWEB)

    Nabeshima, T.; Katoh, A.; Ishimaru, H.; Yoneda, Y.; Ogita, K.; Murase, K.; Ohtsuka, H.; Inari, K.; Fukuta, T.; Kameyama, T. (Meijo Univ., Nagoya (Japan))

    1991-01-01

    We investigated the interrelationship of delayed amnesia, delayed neuronal death and changes in acetylcholine concentration induced by carbon monoxide (CO)-exposure in mice. In the test for retention of the passive avoidance task, amnesia was observed 5 and 7 days after CO-exposure when the mice were exposed to CO 1 day after training; in the case when the mice were exposed to CO 5 and 7 days before training, amnesia was also observed in a retention test given 1 day after training. The number of pyramidal cells in the hippocampal CA1 subfield was lower than that of the control 3, 5 and 7 days after CO-exposure. But the neurodegeneration in the parietal cortex, area 1, was not observed until 7 days after CO-exposure. The findings indicated that the amnesia and the neuronal death were produced after a delay when the mice were exposed to CO. In addition, the delayed amnesia was closely related to the delayed neuronal death in the hippocampal CA1 subfield. Moreover, (3H)glutamate and (3H)glycine binding sites did not change after CO-exposure but, 7 days after CO-exposure, the concentration of acetylcholine and the binding of (3H)quinuclidinyl benzilate in the frontal cortex and the striatum were found to have significantly changed, but those in the hippocampus did not show significant change. Therefore, we suggest that delayed amnesia induced by CO-exposure may result from delayed neuronal death in the hippocampal CA1 subfield and dysfunction in the acetylcholinergic neurons, in the frontal cortex, the striatum and/or the hippocampus.

  4. A novel memristive time-delay chaotic system without equilibrium points

    Science.gov (United States)

    Pham, V.-T.; Vaidyanathan, S.; Volos, C. K.; Jafari, S.; Kuznetsov, N. V.; Hoang, T. M.

    2016-02-01

    Memristor and time-delay are potential candidates for constructing new systems with complex dynamics and special features. A novel time-delay system with a presence of memristive device is proposed in this work. It is worth noting that this memristive time-delay system can generate chaotic attractors although it possesses no equilibrium points. In addition, a circuitry implementation of such time-delay system has been introduced to show its feasibility.

  5. Time-delay damping theory

    Institute of Scientific and Technical Information of China (English)

    洪峰

    2002-01-01

    In this paper, existing damping theories are briefly reviewed. On the basis of the existing damping theories, a new kind of damping theory, i.e., the time-delay damping theory, is developed. In the time-delay damping theory, the damping force is considered to be directly proportional to the increment of displacement. The response analysis of an SDOF time-delay damping system is carried out, and the methods for obtaining the solution for a time-delay damping system in the time domain as well as the frequency domain are given. The comparison between results from different damping theories shows that the time-delay damping theory is both reasonable and convenient.

  6. Group delay functions and its applications in speech technology

    Indian Academy of Sciences (India)

    Hema A Murthy; B Yegnanarayana

    2011-10-01

    Traditionally, the information in speech signals is represented in terms of features derived from short-time Fourier analysis. In this analysis the features extracted from the magnitude of the Fourier transform (FT) are considered, ignoring the phase component. Although the significance of the FT phase was highlighted in several studies over the recent three decades, the features of the FT phase were not exploited fully due to difficulty in computing the phase and also in processing the phase function. The information in the short-time FT phase function can be extracted by processing the derivative of the FT phase, i.e., the group delay function. In this paper, the properties of the group delay functions are reviewed, highlighting the importance of the FT phase for representing information in the speech signal. Methods to process the group delay function are discussed to capture the characteristics of the vocal-tract system in the form of formants or through a modified group delay function. Applications of group delay functions for speech processing are discussed in some detail. They include segmentation of speech into syllable boundaries, exploiting the additive and high resolution properties of the group delay functions. The effectiveness of segmentation of speech, and the features derived from the modified group delay are demonstrated in applications such as language identification, speech recognition and speaker recognition. The paper thus demonstrates the need to exploit the potential of the group delay functions for development of speech systems.

  7. Flight delay performance at Hartsfield-Jackson Atlanta International Airport

    Directory of Open Access Journals (Sweden)

    Grigoriy Yablonsky

    2014-01-01

    Full Text Available Purpose: The main objective of this paper is to determine the annual cyclical flight delays at Hartsfield-Jackson Atlanta International Airport. Then using other data such as annual precipitation, passenger and aircraft traffic volumes and other factors, we attempted to correlate these factors with overall delays. These data could assist airport management in predicting periods of flight delay.Design/methodology/approach: Data were taken and analyzed from the data base “Research and Innovation Technology Administration” (RITA for the years 2005-2011 for Hartsfield-Jackson Atlanta International Airport. The data included 2.8 million flights originating and departing from this airport. Data were also gathered from the National Oceanic and Atmospheric Administration (NOAA showing precipitation. Additional data were gathered from the FAA regarding delay causes, number and types of delays and changes to the infrastructure of ATL airportFindings: There is a repeatable annual pattern of delays at ATL that can be modeled using delay data from the Bureau of Transportation Statistics. This pattern appears to be caused primarily by the frequency and amount of precipitation that falls at ATL and by the amount of flights that arrive and depart at ATL.Originality/value: This information could assist airport operations personnel, FAA air traffic controllers and airlines in anticipating and mitigating delays at specific times of the year.

  8. Analysing End-to-End Packet Delay and Loss in mobile ad hoc networks for interactive audio applications

    OpenAIRE

    Benaissa, Mouna; Lecuire, Vincent; Lepage, Francis; Schaff, André

    2003-01-01

    Interactive audio applications such as audio conferencing and telephony require high constraints on delay, jitter and loss. The packets of these applications must be received without significant loss, with low delay and jitter. When packet loss rate exceeds 10% and one way delay exceeds 150 ms, speech quality can be quite poor. Human conversation tolerates a maximum end-to-end delay of between 150 and 300 milliseconds. In addition, these packets must have a small delay variation to maintain c...

  9. Transport of radioactive materials by air: a national approach to cope with denials and delays

    International Nuclear Information System (INIS)

    Full text: Around 300 nuclear medicine services in the Greater Caribbean depend, almost exclusively, on the airlines to receive radiopharmaceuticals. Less than 20 % of the regional airlines accept radioactive materials in addition to delays and denials, altogether, result in hardships to patients undergoing diagnosis and treatment, despite compliance with regulations. In the international framework leaded by the IAEA to alleviate the difficulties encountered, national approaches are needed to support this effort. The paper presents the Cuban experience regarding statistics of denials and delays by air, generic examples and classification of causes. The role of a Facilitation Working Group and actions taken in communication, awareness, harmonization of regulations, education and training are discussed. The results show a sensitive improvement in the reported instances of denials and delays at domestic level, strongly influenced by the corporative social responsibility of the main national airline and the actions underway. On the other hand, the increasing number of reported denials by international airlines in the last two years, demonstrate how much work must be done at regional and international level. (author)

  10. Attosecond Delays in Molecular Photoionization

    Science.gov (United States)

    Huppert, Martin; Jordan, Inga; Baykusheva, Denitsa; von Conta, Aaron; Wörner, Hans Jakob

    2016-08-01

    We report measurements of energy-dependent photoionization delays between the two outermost valence shells of N2O and H2O . The combination of single-shot signal referencing with the use of different metal foils to filter the attosecond pulse train enables us to extract delays from congested spectra. Remarkably large delays up to 160 as are observed in N2O , whereas the delays in H2O are all smaller than 50 as in the photon-energy range of 20-40 eV. These results are interpreted by developing a theory of molecular photoionization delays. The long delays measured in N2O are shown to reflect the population of molecular shape resonances that trap the photoelectron for a duration of up to ˜110 as. The unstructured continua of H2O result in much smaller delays at the same photon energies. Our experimental and theoretical methods make the study of molecular attosecond photoionization dynamics accessible.

  11. Attosecond delays in molecular photoionization

    CERN Document Server

    Huppert, Martin; Baykusheva, Denitsa; von Conta, Aaron; Wörner, Hans Jakob

    2016-01-01

    We report measurements of energy-dependent attosecond photoionization delays between the two outer-most valence shells of N$_2$O and H$_2$O. The combination of single-shot signal referencing with the use of different metal foils to filter the attosecond pulse train enables us to extract delays from congested spectra. Remarkably large delays up to 160 as are observed in N$_2$O, whereas the delays in H$_2$O are all smaller than 50 as in the photon-energy range of 20-40 eV. These results are interpreted by developing a theory of molecular photoionization delays. The long delays measured in N$_2$O are shown to reflect the population of molecular shape resonances that trap the photoelectron for a duration of up to $\\sim$110 as. The unstructured continua of H$_2$O result in much smaller delays at the same photon energies. Our experimental and theoretical methods make the study of molecular attosecond photoionization dynamics accessible.

  12. Dynamical behaviors in time-delay systems with delayed feedback and digitized coupling

    International Nuclear Information System (INIS)

    We consider a network of delay dynamical systems connected in a ring via unidirectional positive feedback with constant delay in coupling. For the specific case of Mackey–Glass systems on the ring topology, we capture the phenomena of amplitude death, isochronous synchronization and phase-flip bifurcation as the relevant parameters are tuned. Using linear stability analysis and Master Stability Function approach, we predict the region of amplitude death and synchronized states respectively in the parameter space and study the nature of transitions between the different states. For a large number of systems in the same dynamical configuration, we observe splay states, mixed splay states and phase locked clusters. We extend the study to the case of digitized coupling and observe that these emergent states still persist. However, the sampling and quantization reduce the regions of amplitude death and induce phase-flip bifurcation

  13. Dynamical behaviors in time-delay systems with delayed feedback and digitized coupling

    Science.gov (United States)

    Mitra, Chiranjit; Ambika, G.; Banerjee, Soumitro

    2014-12-01

    We consider a network of delay dynamical systems connected in a ring via unidirectional positive feedback with constant delay in coupling. For the specific case of Mackey-Glass systems on the ring topology, we capture the phenomena of amplitude death, isochronous synchronization and phase-flip bifurcation as the relevant parameters are tuned. Using linear stability analysis and master stability function approach, we predict the region of amplitude death and synchronized states respectively in the parameter space and study the nature of transitions between the different states. For a large number of systems in the same dynamical configuration, we observe splay states, mixed splay states and phase locked clusters. We extend the study to the case of digitized coupling and observe that these emergent states still persist. However, the sampling and quantization reduce the regions of amplitude death and induce phase-flip bifurcation.

  14. Time Delay in Molecular Photoionization

    CERN Document Server

    Hockett, P; Villeneuve, D M; Corkum, P B

    2015-01-01

    Time-delays in the photoionization of molecules are investigated. As compared to atomic ionization, the time-delays expected from molecular ionization present a much richer phenomenon, with a strong spatial dependence due to the anisotropic nature of the molecular scattering potential. We investigate this from a scattering theory perspective, and make use of molecular photoionization calculations to examine this effect in representative homonuclear and hetronuclear diatomic molecules, nitrogen and carbon monoxide. We present energy and angle-resolved maps of the Wigner delay time for single-photon valence ionization, and discuss the possibilities for experimental measurements.

  15. On Cucker-Smale model with noise and delay

    OpenAIRE

    Erban, Radek; Haskovec, Jan; Sun, Yongzheng

    2015-01-01

    A generalization of the Cucker-Smale model for collective animal behaviour is investigated. The model is formulated as a system of delayed stochastic differential equations. It incorporates two additional processes which are present in animal decision making, but are often neglected in modelling: (i) stochasticity (imperfections) of individual behaviour; and (ii) delayed responses of individuals to signals in their environment. Sufficient conditions for flocking for the generalized Cucker-Sma...

  16. Factors associated with patient and provider delays for tuberculosis diagnosis and treatment in Asia: a systematic review and meta-analysis.

    Directory of Open Access Journals (Sweden)

    Jing Cai

    Full Text Available Delays in tuberculosis (TB diagnosis and treatment is a major barrier to effective management of the disease. Determining the factors associated with patient and provider delay of TB diagnosis and treatment in Asia may contribute to TB prevention and control.We searched the PubMed, EMBASE and Web of Science for studies that assessed factors associated with delays in care-seeking, diagnosis, or at the beginning of treatment, which were published from January 1992 to September 2014. Two reviewers independently identified studies that were related to our meta-analysis and extracted data from each study. Independent variables were categorized in separate tables for patient and provider delays.Among 45 eligible studies, 40 studies assessed patient delay whereas 30 assessed provider delay. Cross-sectional surveys were used in all but two articles, which included 17 countries and regions. Socio-demographic characteristics, TB-related symptoms and medical examination, and conditions of seeking medical care in TB patients were frequently reported. Male patients and long travel time/distance to the first healthcare provider led to both shorter patient delays [odds ratio (OR (95% confidence intervals, CI = 0.85 (0.78, 0.92; 1.39 (1.08, 1.78] and shorter provider delays [OR (95%CI = 0.96 (0.93, 1.00; 1.68 (1.12, 2.51]. Unemployment, low income, hemoptysis, and positive sputum smears were consistently associated with patient delay [ORs (95%CI = 1.18 (1.07, 1.30, 1.23 (1.02, 1.49, 0.64 (0.40, 1.00, 1.77 (1.07, 2.94, respectively]. Additionally, consultation at a public hospital was associated with provider delay [OR (95%CI = 0.43 (0.20, 0.91].We propose that the major opportunities to reduce delays involve enabling socio-demographic factors and medical conditions. Male, unemployed, rural residence, low income, hemoptysis, positive sputum smear, and long travel time/distance significantly correlated with patient delay. Male, long travel time/distance and

  17. Fundamentals of Delayed Coking Joint Industry Project

    Energy Technology Data Exchange (ETDEWEB)

    Michael Volk; Keith Wisecarver

    2004-09-26

    Delayed coking evolved steadily over the early to mid 1900s to enable refiners to convert high boiling, residual petroleum fractions to light products such as gasoline. Pound for pound, coking is the most energy intensive of any operation in a modern refinery. Large amounts of energy are required to heat the thick, poor-quality petroleum residuum to the 900 to 950 degrees F required to crack the heavy hydrocarbon molecules into lighter, more valuable products. One common misconception of delayed coking is that the product coke is a disadvantage. Although coke is a low valued (near zero economic value) byproduct, compared to transportation fuels, there is a significant worldwide trade and demand for coke as it is an economical fuel. Coke production has increased steadily over the last ten years, with further increases forecast for the foreseeable future. Current domestic production is near 111,000 tons per day. A major driving force behind this increase is the steady decline in crude quality available to refiners. Crude slates are expected to grow heavier with higher sulfur contents while environmental restrictions are expected to significantly reduce the demand for high-sulfur residual fuel oil. Light sweet crudes will continue to be available and in even greater demand than they are today. Refiners will be faced with the choice of purchasing light sweet crudes at a premium price, or adding bottom of the barrel upgrading capability, through additional new investments, to reduce the production of high-sulfur residual fuel oil and increase the production of low-sulfur distillate fuels. A second disadvantage is that liquid products from cokers frequently are unstable, i.e., they rapidly form gum and sediments. Because of intermediate investment and operating costs, delayed coking has increased in popularity among refiners worldwide. Based on the 2000 Worldwide Refining Survey published in the Oil and Gas, the delayed coking capacity for 101 refineries around the world

  18. Interaction of Airspace Partitions and Traffic Flow Management Delay

    Science.gov (United States)

    Palopo, Kee; Chatterji, Gano B.; Lee, Hak-Tae

    2010-01-01

    To ensure that air traffic demand does not exceed airport and airspace capacities, traffic management restrictions, such as delaying aircraft on the ground, assigning them different routes and metering them in the airspace, are implemented. To reduce the delays resulting from these restrictions, revising the partitioning of airspace has been proposed to distribute capacity to yield a more efficient airspace configuration. The capacity of an airspace partition, commonly referred to as a sector, is limited by the number of flights that an air traffic controller can safely manage within the sector. Where viable, re-partitioning of the airspace distributes the flights over more efficient sectors and reduces individual sector demand. This increases the overall airspace efficiency, but requires additional resources in some sectors in terms of controllers and equipment, which is undesirable. This study examines the tradeoff of the number of sectors designed for a specified amount of traffic in a clear-weather day and the delays needed for accommodating the traffic demand. Results show that most of the delays are caused by airport arrival and departure capacity constraints. Some delays caused by airspace capacity constraints can be eliminated by re-partitioning the airspace. Analyses show that about 360 high-altitude sectors, which are approximately today s operational number of sectors of 373, are adequate for delays to be driven solely by airport capacity constraints for the current daily air traffic demand. For a marginal increase of 15 seconds of average delay, the number of sectors can be reduced to 283. In addition, simulations of traffic growths of 15% and 20% with forecasted airport capacities in the years 2018 and 2025 show that delays will continue to be governed by airport capacities. In clear-weather days, for small increases in traffic demand, increasing sector capacities will have almost no effect on delays.

  19. Delays and networked control systems

    CERN Document Server

    Hetel, Laurentiu; Daafouz, Jamal; Johansson, Karl

    2016-01-01

    This edited monograph includes state-of-the-art contributions on continuous time dynamical networks with delays. The book is divided into four parts. The first part presents tools and methods for the analysis of time-delay systems with a particular attention on control problems of large scale or infinite-dimensional systems with delays. The second part of the book is dedicated to the use of time-delay models for the analysis and design of Networked Control Systems. The third part of the book focuses on the analysis and design of systems with asynchronous sampling intervals which occur in Networked Control Systems. The last part of the book exposes several contributions dealing with the design of cooperative control and observation laws for networked control systems. The target audience primarily comprises researchers and experts in the field of control theory, but the book may also be beneficial for graduate students. .

  20. Delay discounting and frontostriatal fiber tracts: a combined DTI and MTR study on impulsive choices in healthy young adults.

    Science.gov (United States)

    Peper, Jiska S; Mandl, René C W; Braams, Barbara R; de Water, Erik; Heijboer, Annemieke C; Koolschijn, P Cédric M P; Crone, Eveline A

    2013-07-01

    Delay discounting, a measure of impulsive choice, has been associated with decreased control of the prefrontal cortex over striatum responses. The anatomical connectivity between both brain regions in delaying gratification remains unknown. Here, we investigate whether the quality of frontostriatal (FS) white matter tracts can predict individual differences in delay-discounting behavior. We use tract-based diffusion tensor imaging and magnetization transfer imaging to measure the microstructural properties of FS fiber tracts in 40 healthy young adults (from 18 to 25 years). We additionally explored whether internal sex hormone levels affect the integrity of FS tracts, based on the hypothesis that sex hormones modulate axonal density within prefrontal dopaminergic circuits. We calculated fractional anisotropy (FA), mean diffusivity (MD), longitudinal diffusivity, radial diffusivity (RD), and magnetization transfer ratio (MTR), a putative measure of myelination, for the FS tract. Results showed that lower integrity within the FS tract (higher MD and RD and lower FA), predicts faster discounting in both sexes. MTR was unrelated to delay-discounting performance. In addition, testosterone levels in males were associated with a lower integrity (higher RD) within the FS tract. Our study provides support for the hypothesis that enhanced structural integrity of white matter fiber bundles between prefrontal and striatal brain areas is associated with better impulse control.

  1. Language Delays in Toddlers: Information for Parents

    Science.gov (United States)

    ... Stages Listen Español Text Size Email Print Share Language Delays in Toddlers: Information for Parents Page Content ... situation or repeats scripts from TV Delays in language Delays in language are the most common types ...

  2. Measuring information-transfer delays.

    Directory of Open Access Journals (Sweden)

    Michael Wibral

    Full Text Available In complex networks such as gene networks, traffic systems or brain circuits it is important to understand how long it takes for the different parts of the network to effectively influence one another. In the brain, for example, axonal delays between brain areas can amount to several tens of milliseconds, adding an intrinsic component to any timing-based processing of information. Inferring neural interaction delays is thus needed to interpret the information transfer revealed by any analysis of directed interactions across brain structures. However, a robust estimation of interaction delays from neural activity faces several challenges if modeling assumptions on interaction mechanisms are wrong or cannot be made. Here, we propose a robust estimator for neuronal interaction delays rooted in an information-theoretic framework, which allows a model-free exploration of interactions. In particular, we extend transfer entropy to account for delayed source-target interactions, while crucially retaining the conditioning on the embedded target state at the immediately previous time step. We prove that this particular extension is indeed guaranteed to identify interaction delays between two coupled systems and is the only relevant option in keeping with Wiener's principle of causality. We demonstrate the performance of our approach in detecting interaction delays on finite data by numerical simulations of stochastic and deterministic processes, as well as on local field potential recordings. We also show the ability of the extended transfer entropy to detect the presence of multiple delays, as well as feedback loops. While evaluated on neuroscience data, we expect the estimator to be useful in other fields dealing with network dynamics.

  3. Tunable silicon CROW delay lines

    Science.gov (United States)

    Morichetti, Francesco; Canciamilla, Antonio; Torregiani, Matteo; Ferrari, Carlo; Melloni, Andrea; Martinelli, Mario

    2010-05-01

    Tunable coupled resonator optical waveguides (CROWs) are powerful and versatile devices that can be used to dynamically control the delay of optical data streams on chip. In this contribution we show that CROW delay lines fabricated on a silicon on insulator (SOI) platform are suitable for applications in the emerging scenario of optical systems at 100 Gbit/s. Issues concerning technology, design, limits and applications of SOI CROWs are discussed. The performances of silicon CROW delay lines activated by thermal tuning are compared to those of glass CROW in terms of power consumption, thermal crosstalk and reconfiguration speed. The continuous delay of 10-ps long optical pulses by 8 bit length is demonstrated by using a silicon CROW with a bandwidth of 87 GHz and made of 12 RRs. At 100 Gbit/s this structure provides comparable figures of merit (fractional delay of 0.75 bit/RR and fractional loss of 0.7 dB per bit-delay) of state-of-the art glass CROW operating at 10 Gbit/s, yet the area of the latter being three order of magnitude larger. The compatibility of silicon CROW with the emerging 100 Gbit/s systems is demonstrated by showing error-free phase-preserving propagation of a 100 Gbit/s return-to-zero (RZ) polarization-division-multiplexing (PolDM) differential quaternary phase shit keying (DQPSK) signal dynamically delayed by the CROW. It is also demonstrated that a silicon CROW can be used in a PolDM system to introduce a polarization selective delay in order to optimize the time interleaving of the two orthogonally polarized data streams.

  4. Deconstructing delayed posttraumatic stress disorder

    OpenAIRE

    Smid, G.E.

    2011-01-01

    According to the Diagnostic and Statistical Manual of Mental Disorders, delayed posttraumatic stress disorder (PTSD) must be diagnosed in individuals fulfilling criteria for PTSD if the onset of symptoms is at least six months after the trauma. The purpose of this thesis was to establish the prevalence of delayed PTSD and to examine factors that may explain its occurrence. We conducted a meta-analysis and examined prospective data from disaster survivors, unaccompanied refugee minors, and arm...

  5. Concurrent Delay in Construction Disputes

    DEFF Research Database (Denmark)

    Cavaleri, Sylvie Cécile

    the delay is contractually defined as a contractor's risk, the contractor is liable to pay liquidated damages to the employer; if it is not, the contractor can under certain circumstances claim an extension of time and in some cases also economic compensation from the employer. The situation where a given...... solutions to the issue of concurrent delay in a comparative perspective between common and civil law systems, with an emphasis on Danish and English law....

  6. 具有时滞和自食的阶段结构的合作系统的周期解的研究%The study of Periodic Solution a Nonautonomous Stage-Structured System With Time Delay and Cannibalism Two Kinds of Additive Maps on Operator Algebras

    Institute of Scientific and Technical Information of China (English)

    李秋英; 贾建文

    2006-01-01

    In this paper, we consider a cooperative model,which has a discrete delay, stage structure and cannibalism. By using the continuation theorem of coincidence degree theory, a sufficient condition is obtained for the existence of a positive periodic solution of this system.%本文讨论一类具有时滞、阶段结构及自食的非自治合作系统的动力学行为,利用重合度理论中的的连续性定理,得到系统正周期解存在的充分条件.

  7. Basin stability in delayed dynamics

    Science.gov (United States)

    Leng, Siyang; Lin, Wei; Kurths, Jürgen

    2016-02-01

    Basin stability (BS) is a universal concept for complex systems studies, which focuses on the volume of the basin of attraction instead of the traditional linearization-based approach. It has a lot of applications in real-world systems especially in dynamical systems with a phenomenon of multi-stability, which is even more ubiquitous in delayed dynamics such as the firing neurons, the climatological processes, and the power grids. Due to the infinite dimensional property of the space for the initial values, how to properly define the basin’s volume for delayed dynamics remains a fundamental problem. We propose here a technique which projects the infinite dimensional initial state space to a finite-dimensional Euclidean space by expanding the initial function along with different orthogonal or nonorthogonal basis. A generalized concept of basin’s volume in delayed dynamics and a highly practicable calculating algorithm with a cross-validation procedure are provided to numerically estimate the basin of attraction in delayed dynamics. We show potential applicabilities of this approach by applying it to study several representative systems of biological or/and physical significance, including the delayed Hopfield neuronal model with multistability and delayed complex networks with synchronization dynamics.

  8. Reaction diffusion equation with spatio-temporal delay

    Science.gov (United States)

    Zhao, Zhihong; Rong, Erhua

    2014-07-01

    We investigate reaction-diffusion equation with spatio-temporal delays, the global existence, uniqueness and asymptotic behavior of solutions for which in relation to constant steady-state solution, included in the region of attraction of a stable steady solution. It is shown that if the delay reaction function satisfies some conditions and the system possesses a pair of upper and lower solutions then there exists a unique global solution. In terms of the maximal and minimal constant solutions of the corresponding steady-state problem, we get the asymptotic stability of reaction-diffusion equation with spatio-temporal delay. Applying this theory to Lotka-Volterra model with spatio-temporal delay, we get the global solution asymptotically tend to the steady-state problem's steady-state solution.

  9. CALIBRATION OF LOW-FREQUENCY, WIDE-FIELD RADIO INTERFEROMETERS USING DELAY/DELAY-RATE FILTERING

    International Nuclear Information System (INIS)

    We present a filtering technique that can be applied to individual baselines of wide-bandwidth, wide-field interferometric data to geometrically select regions on the celestial sphere that contain primary calibration sources. The technique relies on the Fourier transformation of wide-band frequency spectra from a given baseline to obtain one-dimensional 'delay images', and then the transformation of a time-series of delay images to obtain two-dimensional 'delay/delay-rate images'. Source selection is possible in these images given appropriate combinations of baseline, bandwidth, integration time, and source location. Strong and persistent radio frequency interference (RFI) limits the effectiveness of this source selection owing to the removal of data by RFI excision algorithms. A one-dimensional, complex CLEAN algorithm has been developed to compensate for RFI-excision effects. This approach allows CLEANed, source-isolated data to be used to isolate bandpass and primary beam gain functions. These techniques are applied to data from the Precision Array for Probing the Epoch of Reionization as a demonstration of their value in calibrating a new generation of low-frequency radio interferometers with wide relative bandwidths and large fields of view.

  10. Various Forms of Project Delay in the Construction Industry

    Directory of Open Access Journals (Sweden)

    Nurbasirah Mohamed Alias

    2013-09-01

    Full Text Available Project delay can be defined as an incident that causes extended time in order to complete all or part of a particular project successfully. In other words, delay is the time overrun, either ahead of the date for project completion specified by the contract or further than the extensive contract period where an addition of time has been granted. It should be pointed out that the project delay in the construction industry is a universal or large-scale observable fact affecting not only the construction industry but the overall economy of countries too. As far as world construction industry is concerned, project delays are common problems in the construction industries; particularly most common is in the housing development industries. This paper will present different types of project delay that took place around the world. Project delay involves diverse complicated issues all of which are continuously of crucial importance to the parties to the construction contract. These issues concern right to convalesce costs of the project delay or the need to lengthen the project with the considerable right to recovery costs for adjustments to the contract schedules.

  11. On Delay-independent Stability Criteria for Linear Time-delay Systems

    Institute of Scientific and Technical Information of China (English)

    Ai-Guo Wu; Guang-Ren Duan

    2007-01-01

    Several LMI representations for delay-independence stability are proposed by applying Projection Lemma and the socalled "Small Scalar Method". These criteria realize the elimination of the products coupling the system matrices and Lyapunov matrices by introducing some additional matrices. When they are applied to robust stability analysis for polytopic uncertain systems,the vertex-dependent Lyapunov functions are allowed, so less conservative results can be obtained. A numerical example is employed to illustrate the effect of these proposed criteria.

  12. Effects of Delayed Second Cochlear Implant

    Institute of Scientific and Technical Information of China (English)

    XIA Rui-ming; WU Xi-hong; JANG Zi-gang; JING Yuan-yuan; LIN Yun-juan; YU Li-sheng

    2006-01-01

    Objective Since Helms' successful bilateral cochlear implantation with good results in 1996, there have been increasing number of reports on bilateral cochlear implantation. Most second device have been implantated within one year after the first. Considering effects of long time auditory deprivation, it is not clear whether a delayed second cochlear implant serves to add additional benefits and how it may interact with central nervous system plasticity. Methods Three cases who received delayed second cochlear implants at People's Hospital of Peking University from 2002 to 2005 were reviewed. The interval between the first and second implants was longer than 2 years in all three patients. Sound perception, and unilateral/bilateral speech discrimination in quiet and noise were evaluated. In addition, GAP detection test was conducted in one patient. Results In one case,having both implants on provided improved performance compared to using only one implant both in quiet and noise. Presumably due to visual interference from lip-reading or short interval between second implant and testing,one patient showed no improvement from using the second implant either in quiet or noise, while the last case demonstrated additional benefits from the second implant only in quiet. In all three patients, performance in recognizing the four tones in Mandarin was superior over word recognition. Conclusions Considerable plasticity in the cerebral auditory center is preserved, despite long acoustic deprivation in some children who have received unilateral cochlear implant. Delayed second implants can result in significant improvements in some of these children. Visual interference from lip-reading may be an obstacle during retraining. The better recognition of tones in the Mandarin language may represent a different sound discrimination mechanism in the auditory system,although it may also be related to the signal processing mechanisms of the implant used (MED-EL COMBI 40+).

  13. Model Additional Protocol

    International Nuclear Information System (INIS)

    Since the end of the cold war a series of events has changed the circumstances and requirements of the safeguards system. The discovery of a clandestine nuclear weapons program in Iraq, the continuing difficulty in verifying the initial report of Democratic People's Republic of Korea upon entry into force of their safeguards agreement, and the decision of the South African Government to give up its nuclear weapons program and join the Treaty on the Non-Proliferation of Nuclear Weapons have all played a role in an ambitious effort by IAEA Member States and the Secretariat to strengthen the safeguards system. A major milestone in this effort was reached in May 1997 when the IAEA Board of Governors approved a Model Protocol Additional to Safeguards Agreements. The Model Additional Protocol was negotiated over a period of less than a year by an open-ended committee of the Board involving some 70 Member States and two regional inspectorates. The IAEA is now in the process of negotiating additional protocols, State by State, and implementing them. These additional protocols will provide the IAEA with rights of access to information about all activities related to the use of nuclear material in States with comprehensive safeguards agreements and greatly expanded physical access for IAEA inspectors to confirm or verify this information. In conjunction with this, the IAEA is working on the integration of these measures with those provided for in comprehensive safeguards agreements, with a view to maximizing the effectiveness and efficiency, within available resources, the implementation of safeguards. Details concerning the Model Additional Protocol are given. (author)

  14. Earth system commitments due to delayed mitigation

    International Nuclear Information System (INIS)

    As long as global CO2 emissions continue to increase annually, long-term committed Earth system changes grow much faster than current observations. A novel metric linking this future growth to policy decisions today is the mitigation delay sensitivity (MDS), but MDS estimates for Earth system variables other than peak temperature (ΔT max) are missing. Using an Earth System Model of Intermediate Complexity, we show that the current emission increase rate causes a ΔT max increase roughly 3–7.5 times as fast as observed warming, and a millenial steric sea level rise (SSLR) 7–25 times as fast as observed SSLR, depending on the achievable rate of emission reductions after the peak of emissions. These ranges are only slightly affected by the uncertainty range in equilibrium climate sensitivity, which is included in the above values. The extent of ocean acidification at the end of the century is also strongly dependent on the starting time and rate of emission reductions. The preservable surface ocean area with sufficient aragonite supersaturation for coral reef growth is diminished globally at an MDS of roughly 25%–80% per decade. A near-complete loss of this area becomes unavoidable if mitigation is delayed for a few years to decades. Also with respect to aragonite, 12%–18% of the Southern Ocean surface become undersaturated per decade, if emission reductions are delayed beyond 2015–2040. We conclude that the consequences of delaying global emission reductions are much better captured if the MDS of relevant Earth system variables is communicated in addition to current trends and total projected future changes. (letter)

  15. Earth system commitments due to delayed mitigation

    Science.gov (United States)

    Pfister, Patrik L.; Stocker, Thomas F.

    2016-01-01

    As long as global CO2 emissions continue to increase annually, long-term committed Earth system changes grow much faster than current observations. A novel metric linking this future growth to policy decisions today is the mitigation delay sensitivity (MDS), but MDS estimates for Earth system variables other than peak temperature (ΔT max) are missing. Using an Earth System Model of Intermediate Complexity, we show that the current emission increase rate causes a ΔT max increase roughly 3-7.5 times as fast as observed warming, and a millenial steric sea level rise (SSLR) 7-25 times as fast as observed SSLR, depending on the achievable rate of emission reductions after the peak of emissions. These ranges are only slightly affected by the uncertainty range in equilibrium climate sensitivity, which is included in the above values. The extent of ocean acidification at the end of the century is also strongly dependent on the starting time and rate of emission reductions. The preservable surface ocean area with sufficient aragonite supersaturation for coral reef growth is diminished globally at an MDS of roughly 25%-80% per decade. A near-complete loss of this area becomes unavoidable if mitigation is delayed for a few years to decades. Also with respect to aragonite, 12%-18% of the Southern Ocean surface become undersaturated per decade, if emission reductions are delayed beyond 2015-2040. We conclude that the consequences of delaying global emission reductions are much better captured if the MDS of relevant Earth system variables is communicated in addition to current trends and total projected future changes.

  16. Delayed bedtimes and obsessive-compulsive symptoms.

    Science.gov (United States)

    Coles, Meredith E; Schubert, Jessica R; Sharkey, Katherine M

    2012-10-01

    There is increasing recognition of an important interplay between psychiatric disorders and sleep. Clinical observations and several empirical studies have shown that later bedtimes are associated with obsessive-compulsive disorder (OCD). This study examined the relation of delayed bedtimes (DBs) and symptoms of OCD. Two hundred and sixty-six undergraduates completed a battery of questionnaires assessing sleep patterns, mood, and obsessive-compulsive (OC) symptoms. Results showed that participants with DBs reported increased rates of OC symptoms, as compared with non-DB participants. Further, this relation remained significant when controlling for negative affect. Additional work examining the interplay between sleep and OC symptoms is warranted. PMID:22946735

  17. Optimal state estimation over communication channels with random delays

    KAUST Repository

    Mahmoud, Magdi S.

    2013-04-01

    This paper is concerned with the optimal estimation of linear systems over unreliable communication channels with random delays. The measurements are delivered without time stamp, and the probabilities of time delays are assumed to be known. Since the estimation is time-driven, the actual time delays are converted into virtual time delays among the formulation. The receiver of estimation node stores the sum of arrived measurements between two adjacent processing time instants and also counts the number of arrived measurements. The original linear system is modeled as an extended system with uncertain observation to capture the feature of communication, then the optimal estimation algorithm of systems with uncertain observations is proposed. Additionally, a numerical simulation is presented to show the performance of this work. © 2013 The Franklin Institute.

  18. Delayed Gastric Emptying after Living Donor Hepatectomy for Liver Transplantation

    Directory of Open Access Journals (Sweden)

    Hanjay Wang

    2014-01-01

    Full Text Available Delayed gastric emptying is a significant postoperative complication of living donor hepatectomy for liver transplantation and may require endoscopic or surgical intervention in severe cases. Although the mechanism of posthepatectomy delayed gastric emptying remains unknown, vagal nerve injury during intraoperative dissection and adhesion formation postoperatively between the stomach and cut liver surface are possible explanations. Here, we present the first reported case of delayed gastric emptying following fully laparoscopic hepatectomy for living donor liver transplantation. Additionally, we also present a case in which symptoms developed after open right hepatectomy, but for which dissection for left hepatectomy was first performed. Through our experience and these two specific cases, we favor a neurovascular etiology for delayed gastric emptying after hepatectomy.

  19. Geometric representation for numerical stability region of linear multistep methods

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Studies the numerical stability region of linear multistep(LM) methods applied to linear test equation of the formy′(t) = ay(t) + by( t - 1), t > 0, y( t ) = g( t ) - 1 ≤ t ≤ 0, a,b ∈ R, proves through delaydependent stability analysis that the intersection of stability regions of the equation and the method is not empty, in addition to approaches to the boundary of the delay differential equation(DDEs) in the limiting case of stepsize boundary of the stability region of linear multistep methods.

  20. Targeted resequencing of the pericentromere of chromosome 2 linked to constitutional delay of growth and puberty.

    Directory of Open Access Journals (Sweden)

    Diana L Cousminer

    Full Text Available Constitutional delay of growth and puberty (CDGP is the most common cause of pubertal delay. CDGP is defined as the proportion of the normal population who experience pubertal onset at least 2 SD later than the population mean, representing 2.3% of all adolescents. While adolescents with CDGP spontaneously enter puberty, they are at risk for short stature, decreased bone mineral density, and psychosocial problems. Genetic factors contribute heavily to the timing of puberty, but the vast majority of CDGP cases remain biologically unexplained, and there is no definitive test to distinguish CDGP from pathological absence of puberty during adolescence. Recently, we published a study identifying significant linkage between a locus at the pericentromeric region of chromosome 2 (chr 2 and CDGP in Finnish families. To investigate this region for causal variation, we sequenced chr 2 between the genomic coordinates of 79-124 Mb (genome build GRCh37 in the proband and affected parent of the 13 families contributing most to this linkage signal. One gene, DNAH6, harbored 6 protein-altering low-frequency variants (< 6% in the Finnish population in 10 of the CDGP probands. We sequenced an additional 135 unrelated Finnish CDGP subjects and utilized the unique Sequencing Initiative Suomi (SISu population reference exome set to show that while 5 of these variants were present in the CDGP set, they were also present in the Finnish population at similar frequencies. Additional variants in the targeted region could not be prioritized for follow-up, possibly due to gaps in sequencing coverage or lack of functional knowledge of non-genic genomic regions. Thus, despite having a well-characterized sample collection from a genetically homogeneous population with a large population-based reference sequence dataset, we were unable to pinpoint variation in the linked region predisposing delayed puberty. This study highlights the difficulties of detecting genetic variants

  1. Stability of nonlinearly-perturbed systems with time varying delay using LMIs

    Institute of Scientific and Technical Information of China (English)

    S.Jeeva Sathya Theesar; P.Balasubramaniam

    2013-01-01

    This paper studies delay dependent robust stability and the stabilization problem of nonlinear perturbed systems with time varying delay. A new set of sufficient conditions for the stability of open as wel as close loop systems are obtained in the sense of Lyapunov-Krasovski . To reduce the conservatism, the work exploits the idea of splitting the delay interval into multiple equal regions so that less information on the time delay can be imposed to derive the results. The derived criterion not only improves the upper bounds of the time delay but also does not require the derivative of the delay to be known at prior. Easily testable suffi-cient criteria are presented in terms of linear matrix inequalities. It is shown that the derived conditions are very less conservative while comparing the maximum al owable upper bound of delay with the existing results in literature.

  2. 49 CFR 236.563 - Delay time.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Delay time. 236.563 Section 236.563 Transportation... Cab Signal Systems Rules and Instructions; Locomotives § 236.563 Delay time. Delay time of automatic... requirements of § 236.24 shall take into consideration the delay time....

  3. Time-domain nature of group delay

    Institute of Scientific and Technical Information of China (English)

    王建武; 冯正和

    2015-01-01

    The characteristic of group delay is analyzed based on an electronic circuit, and its time-domain nature is studied with time-domain simulation and experiment. The time-domain simulations and experimental results show that group delay is the delay of the energy center of the amplitude-modulated pulse, rather than the propagation delay of the electromagnetic field. As group velocity originates from the definition of group delay and group delay is different from the propagation delay, the superluminality or negativity of group velocity does not mean the superluminal or negative propagation of the electromagnetic field.

  4. High-speed delay tuning of slow light in pin-diode-incorporated photonic crystal waveguide.

    Science.gov (United States)

    Hayakawa, Ryo; Ishikura, Norihiro; Nguyen, Hong C; Baba, Toshihiko

    2013-08-01

    We demonstrate the high-speed electrical delay tuning of slow light pulses using Si photonic crystal waveguides. The device has an i-region-chirped pin diode, within which thermo-optic and carrier plasma effects are generated by forward bias. The former changes the delay up to 62 ps for the DC bias. The latter changes the delay for 1 Gbps pseudo random bit sequence tuning signals, which will be applicable to advanced time-domain optical signal processing. PMID:23903110

  5. Drain Current Response Delay of FD-SOI MOSFETs in RF Operation

    OpenAIRE

    Shimizu, Yoshiyuki; Kim, Gue Chol; Murakami, Bunsei; Ueda, Keisuke; Utsurogi, Yoshihiro; Cha, Sungwoo; Matsuoka, Toshimasa; Taniguchi, Kenji

    2004-01-01

    We investigated the frequency dependences of Y22 of FD-SOI MOSFETs, in which the drain current response delay is observed for the first time. Short channel FD-SOI devices operating in linear region show significant drain current response delay. It is confirmed that FD-SOI MOSFET's RF behavior can be well reproduced with the proposed model including the drain current response delay.

  6. Two vicious circles contributing to a diagnostic delay for tuberculosis patients in Arkhangelsk

    OpenAIRE

    Vladimir N. Kuznetsov; Grjibovski, Andrej M.; Mariandyshev, Andrej O.; Johansson, Eva; Gunnar A. Bjune

    2014-01-01

    Setting: Delay in tuberculosis (TB) diagnosis increases the infectious pool in the community and the risk of development of resistance of mycobacteria, which results in an increased number of deaths.Objective: To describe patients’ and doctors’ perceptions of diagnostic delay in TB patients in the Arkhangelsk region and to develop a substantive model to better understand the mechanisms of how these delays are linked to each other.Design: A grounded theory approach was used to study the phenom...

  7. Factors Influencing Pre-hospital Patient Delay in Patients with Acute Myocardial Infarction

    Institute of Scientific and Technical Information of China (English)

    La Xie; Su-Fang Huang∗; You-Zhen Hu

    2015-01-01

    Acute myocardial infarction ( AMI) is a dangerous disease with a high mortality rate. For AMI patients, the outcome of the patients depends on time to beginning of effective treatment in addition to other factors such as severity of disease and involved vessels etc. The key is whether reperfusion therapy is started early enough after the onset of symptoms, and the benefit of reperfu-sion therapy depends on the time, too. The delay of AMI treatment is divided into pre-hospital de-lay and in-hospital delay. In-hospital delay, Door-to-Balloon Time, has been well controlled. Pre-hospital delay, accounting for 75% of the total delay time, is the most important factor affect-ing AMI treatment. Patient delay ( PD) time for AMI patients is summarised in this study.

  8. Livermore blasted for project delay

    CERN Multimedia

    1999-01-01

    In a 12 page report issued last week, a review committee set up by the University of California has concluded that mismanagement and poor planning are to blame for significant cost overruns and delays in the construction of NIF, the worlds largest laser (1 page).

  9. Diagnostic Delay in Rheumatoid Arthritis

    DEFF Research Database (Denmark)

    Mølbaek, Karen; Hørslev-Petersen, Kim; Primdahl, Jette

    2016-01-01

    BACKGROUND: To prevent joint damage among patients with rheumatoid arthritis (RA), there is a need to minimize delays from the onset of symptoms until the initiation of appropriate therapy. The present study explored the factors that have an impact on the time it takes for Danish patients with RA...

  10. Delayed School Entry in Uganda

    Science.gov (United States)

    Moyi, Peter

    2011-01-01

    Since 1997 Uganda has seen a large increase in school enrolment. Despite this increased enrolment, universal education has remained elusive. Many children enrol in school, but not at the recommended age, and they drop out before completing school. This article focuses on one of these problems--delayed school entry. What household factors are…

  11. Design flaw could delay collider

    CERN Multimedia

    Cho, Adrian

    2007-01-01

    "A magnet for the Large Hadron Collider (LHC) failed during a key test at the European particle physics laboratory CERN last week. Physicists and engineers will have to repair the damaged magnet and retrofit others to correct the underlynig design flaw, which could delay the start-up of the mammouth subterranean machine." (1,5 page)

  12. Advanced optical delay line demonstrator

    NARCIS (Netherlands)

    Dool, T.C. van den; Kamphues, F.G.; Fouss, B.; Henrioulle, K.; Hogenhuis, H.

    2004-01-01

    TNO TPD, in cooperation with Micromega-Dynamics and Dutch Space, has designed an advanced Optical Delay Line (ODL) for use in future ground based and space interferometry missions. The work is performed under NIVR contract in preparation for GENIE and DARWIN. Using the ESO PRIMA DDL requirements as

  13. Deconstructing delayed posttraumatic stress disorder

    NARCIS (Netherlands)

    Smid, G.E.

    2011-01-01

    According to the Diagnostic and Statistical Manual of Mental Disorders, delayed posttraumatic stress disorder (PTSD) must be diagnosed in individuals fulfilling criteria for PTSD if the onset of symptoms is at least six months after the trauma. The purpose of this thesis was to establish the prevale

  14. Providing Delay Guarantees in Bluetooth

    NARCIS (Netherlands)

    Ait Yaiz, Rachid; Heijenk, Geert; Titsworth, F.

    2003-01-01

    Bluetooth polling, also referred to as Bluetooth MAC scheduling or intra-piconet scheduling, is the mechanism that schedules the traffic between the participants in a Bluetooth network. Hence, this mechanism is highly determining with respect to the delay packets experience in a Bluetooth network. I

  15. Mechanism of delayed double ionization in a strong laser field

    OpenAIRE

    Mauger, Francois; Kamor, Adam; Chandre, Cristel; UZer, Turgay

    2011-01-01

    When intense laser pulses release correlated electrons, the time delay between the ionizations may last more than one laser cycle. We show that this "Recollision-Excitation with Subsequent Ionization" pathway originates from the inner electron being promoted to a sticky region by a recollision where it is trapped for a long time before ionizing. We identify the mechanism which regulates this region, and predict oscillations in the double ionization yield with laser intensity.

  16. Inactivation of IL11 signaling causes craniosynostosis, delayed tooth eruption, and supernumerary teeth

    DEFF Research Database (Denmark)

    Nieminen, Pekka; Morgan, Neil V; Fenwick, Aimée L;

    2011-01-01

    teeth. We performed homozygosity mapping in three unrelated consanguineous Pakistani families and localized the syndrome to a region in chromosome 9. Mutational analysis of candidate genes in the region revealed that all affected children harbored homozygous missense mutations (c.662C>G [p.Pro221Arg], c......Craniosynostosis and supernumerary teeth most often occur as isolated developmental anomalies, but they are also separately manifested in several malformation syndromes. Here, we describe a human syndrome featuring craniosynostosis, maxillary hypoplasia, delayed tooth eruption, and supernumerary.......734C>G [p.Ser245Cys], or c.886C>T [p.Arg296Trp]) in IL11RA (encoding interleukin 11 receptor, alpha) on chromosome 9p13.3. In addition, a homozygous nonsense mutation, c.475C>T (p.Gln159X), and a homozygous duplication, c.916_924dup (p.Thr306_Ser308dup), were observed in two north European families...

  17. Data Mining for Understanding and Improving Decision-making Affecting Ground Delay Programs

    Science.gov (United States)

    Kulkarni, Deepak; Wang, Yao; Sridhar, Banavar

    2013-01-01

    The continuous growth in the demand for air transportation results in an imbalance between airspace capacity and traffic demand. The airspace capacity of a region depends on the ability of the system to maintain safe separation between aircraft in the region. In addition to growing demand, the airspace capacity is severely limited by convective weather. During such conditions, traffic managers at the FAA's Air Traffic Control System Command Center (ATCSCC) and dispatchers at various Airlines' Operations Center (AOC) collaborate to mitigate the demand-capacity imbalance caused by weather. The end result is the implementation of a set of Traffic Flow Management (TFM) initiatives such as ground delay programs, reroute advisories, flow metering, and ground stops. Data Mining is the automated process of analyzing large sets of data and then extracting patterns in the data. Data mining tools are capable of predicting behaviors and future trends, allowing an organization to benefit from past experience in making knowledge-driven decisions.

  18. Fundamentals of Delayed Coking Joint Industry Project

    Energy Technology Data Exchange (ETDEWEB)

    Michael Volk Jr; Keith Wisecarver

    2005-10-01

    Delayed coking evolved steadily over the early to mid 1900s to enable refiners to convert high boiling, residual petroleum fractions to light products such as gasoline. Pound for pound, coking is the most energy intensive of any operation in a modern refinery. Large amounts of energy are required to heat the thick, poor-quality petroleum residuum to the 900 to 950 degrees F required to crack the heavy hydrocarbon molecules into lighter, more valuable products. One common misconception of delayed coking is that the product coke is a disadvantage. Although coke is a low valued (near zero economic value) byproduct, compared to transportation fuels, there is a significant worldwide trade and demand for coke as it is an economical fuel. Coke production has increased steadily over the last ten years, with further increases forecast for the foreseeable future. Current domestic production is near 111,000 tons per day. A major driving force behind this increase is the steady decline in crude quality available to refiners. Crude slates are expected to grow heavier with higher sulfur contents while environmental restrictions are expected to significantly reduce the demand for high-sulfur residual fuel oil. Light sweet crudes will continue to be available and in even greater demand than they are today. Refiners will be faced with the choice of purchasing light sweet crudes at a premium price, or adding bottom of the barrel upgrading capability, through additional new investments, to reduce the production of high-sulfur residual fuel oil and increase the production of low-sulfur distillate fuels. A second disadvantage is that liquid products from cokers frequently are unstable, i.e., they rapidly form gum and sediments. Because of intermediate investment and operating costs, delayed coking has increased in popularity among refiners worldwide. Based on the 2000 Worldwide Refining Survey published in the Oil and Gas, the delayed coking capacity for 101 refineries around the world

  19. Conical-Domain Model for Estimating GPS Ionospheric Delays

    Science.gov (United States)

    Sparks, Lawrence; Komjathy, Attila; Mannucci, Anthony

    2009-01-01

    -latitudes under disturbed conditions, the accuracy of SBAS systems based upon the thin-shell model suffers due to the presence of complex ionospheric structure, high delay values, and large electron density gradients. Interpolation on the vertical delay grid serves as an additional source of delay error. The conical-domain model permits direct computation of the user s slant delay estimate without the intervening use of a vertical delay grid. The key is to restrict each fit of GPS measurements to a spatial domain encompassing signals from only one satellite. The conical domain model is so named because each fit involves a group of GPS receivers that all receive signals from the same GPS satellite (see figure); the receiver and satellite positions define a cone, the satellite position being the vertex. A user within a given cone evaluates the delay to the satellite directly, using (1) the IPP coordinates of the line of sight to the satellite and (2) broadcast fit parameters associated with the cone. The conical-domain model partly resembles the thin-shell model in that both models reduce an inherently four-dimensional problem to two dimensions. However, unlike the thin-shell model, the conical domain model does not involve any potentially erroneous simplifying assumptions about the structure of the ionosphere. In the conical domain model, the initially four-dimensional problem becomes truly two-dimensional in the sense that once a satellite location has been specified, any signal path emanating from a satellite can be identified by only two coordinates; for example, the IPP coordinates. As a consequence, a user s slant-delay estimate converges to the correct value in the limit that the receivers converge to the user s location (or, equivalently, in the limit that the measurement IPPs converge to the user s IPP).

  20. Impact of early or delayed elective resection in complicated diverticulitis

    Institute of Scientific and Technical Information of China (English)

    Kai Bachmann; Geeske Krause; Tamina Rawnaq; Lena Tomkotter; Yogesh Vashist; Shanly Shahmiri; Jakob R Izbicki; Maximilian Bockhorn

    2011-01-01

    AIM: To investigate the outcomes of early and delayed elective resection after initial antibiotic treatment in patients with complicated diverticulitis.METHODS: The study, a non-randomized comparison of the two approaches, included 421 consecutive patients who underwent surgical resection for complicated sigmoid diverticulitis (Hinchey classification Ⅰ-Ⅱ) at the Department of Surgery, University Medical Center Hamburg-Eppendorf between 2004 and 2009. The operating procedure, duration of hospital and intensive care unit stay, outcome, complications and socioeconomic costs were analyzed, with comparison made between the early and delayed elective resection strategies. RESULTS: The severity of the diverticulitis and American Society of Anesthesiologists score were comparable for the two groups. Patients who underwent delayed elective resection had a shorter hospital stay and operating time, and the rate of successfully completed laparoscopic resections was higher (80% vs 75%). Eight patients who were scheduled for delayed elective resection required urgent surgery because of complications of the diverticulitis, which resulted in a high rate of morbidity. Analysis of the socioeconomic effects showed that hospitalization costs were significantly higher for delayed elective resection compared with early elective resection (9296 € ± 694 € vs 8423 € ± 968 €; P = 0.001). Delayed elective resection showed a trend toward lower complications, and the operation appeared simpler to perform than early elective resection. Nevertheless, delayed elective resection carries a risk of complications occurring during the period of 6-8 wk that could necessitate an urgent resection with its consequent high morbidity, which counterbalanced many of the advantages. CONCLUSION: Overall, early elective resection for complicated, non-perforated diverticulitis is shown to be a suitable alternative to delayed elective resection after 6-8 wk, with additional beneficial socioeconomic

  1. Distributed delays stabilize neural feedback systems

    CERN Document Server

    Meyer, Ulrike; Chakrabarty, Saurish; Brandt, Sebastian F; Luksch, Harald; Wessel, Ralf

    2007-01-01

    We consider the effect of distributed delays in neural feedback systems. The avian optic tectum is reciprocally connected with the nucleus isthmi. Extracellular stimulation combined with intracellular recordings reveal a range of signal delays from 4 to 9 ms between isthmotectal elements. This observation together with prior mathematical analysis concerning the influence of a delay distribution on system dynamics raises the question whether a broad delay distribution can impact the dynamics of neural feedback loops. For a system of reciprocally connected model neurons, we found that distributed delays enhance system stability in the following sense. With increased distribution of delays, the system converges faster to a fixed point and converges slower toward a limit cycle. Further, the introduction of distributed delays leads to an increased range of the average delay value for which the system's equilibrium point is stable. The enhancement of stability with increasing delay distribution is caused by the int...

  2. Experimental Evaluation of FSM-Based Testing Cost for Time-Delay Systems

    OpenAIRE

    Zheng Wei; Wu Xiaoxue; Cai Lu; Hu Desheng

    2014-01-01

    With time-delay systems arising, time-delay system testing has attracted much attention. Additionally, evaluating the cost and effectiveness is required to make a good test strategy in practice. In this paper, we take time-delay and other five factors (state number, input number, output number, completeness degree, and accessibility degree) into account and present a timer embedded FSM (TEFSM) model to design a comparative strategy for assessing the coverage criteria and test suites generati...

  3. Coping with persistent environmental problems: systemic delays in reducing eutrophication of the Baltic Sea

    Directory of Open Access Journals (Sweden)

    Riku Varjopuro

    2014-12-01

    Full Text Available In this paper we focus on systemic delays in the Baltic Sea that cause the problem of eutrophication to persist. These problems are demonstrated in our study by addressing three types of delays: (1 decision delay: the time it takes for an idea or perceived need to be launched as a policy; (2 implementation delay: the time from the launch of a policy to the actual implementation; (3 ecosystem delay: the time difference between the implementation and an actual measurable effects. A policy process is one characterized by delays. It may take years from problem identification to a decision to taking action and several years further for actual implementation. Ecosystem responses to measures illustrate that feedback can keep the ecosystem in a certain state and cause a delay in ecosystem response. These delays can operate on decadal scales. Our aim in this paper is to analyze these systemic delays and especially to discuss how the critical delays can be better addressed in marine protection policies by strengthening the adaptive capacity of marine protection. We conclude that the development of monitoring systems and reflexive, participatory analysis of dynamics involved in the implementation are keys to improve understanding of the systemic delays. The improved understanding is necessary for the adaptive management of a persistent environmental problem. In addition to the state of the environment, the monitoring and analysis should be targeted also at the implementation of policies to ensure that the societies are investing in the right measures.

  4. Daffodil flower delay senescence in cut Iris flowers

    NARCIS (Netherlands)

    Doorn, van W.G.; Sinz, A.; Tomassen, M.M.M.

    2004-01-01

    Visible symptoms of tepal senescence in cut Iris x hollandica (cv. Blue Magic) flowers were delayed by placing one cut daffodil flower (Narcissus pseudonarcissus, cv. Carlton) in the same vase. Addition of mucilage, exuded by daffodil stems, to the vase water had the same effect as the flowering daf

  5. The Child with Delayed Language: Assessment and Management

    OpenAIRE

    Tervo, Raymond C.; Kinney, Cheryl A.

    1981-01-01

    Speech and language disorders are the most common developmental problems among preschool children. Early detection and remediation of delayed language development are important in helping the child establish appropriate social behavior and acquire additional information about the world through the use of language.

  6. Delay-dependent finite-time boundedness of a class of Markovian switching neural networks with time-varying delays.

    Science.gov (United States)

    Zhong, Qishui; Cheng, Jun; Zhao, Yuqing

    2015-07-01

    In this paper, a novel method is developed for delay-dependent finite-time boundedness of a class of Markovian switching neural networks with time-varying delays. New sufficient condition for stochastic boundness of Markovian jumping neural networks is presented and proved by an newly augmented stochastic Lyapunov-Krasovskii functional and novel activation function conditions, the state trajectory remains in a bounded region of the state space over a given finite-time interval. Finally, a numerical example is given to illustrate the efficiency and less conservative of the proposed method.

  7. Delay locked loop integrated circuit.

    Energy Technology Data Exchange (ETDEWEB)

    Brocato, Robert Wesley

    2007-10-01

    This report gives a description of the development of a Delay Locked Loop (DLL) integrated circuit (IC). The DLL was developed and tested as a stand-alone IC test chip to be integrated into a larger application specific integrated circuit (ASIC), the Quadrature Digital Waveform Synthesizer (QDWS). The purpose of the DLL is to provide a digitally programmable delay to enable synchronization between an internal system clock and external peripherals with unknown clock skew. The DLL was designed and fabricated in the IBM 8RF process, a 0.13 {micro}m CMOS process. It was designed to operate with a 300MHz clock and has been tested up to 500MHz.

  8. Delayed neurological deterioration due to progressive pneumocephalus

    Directory of Open Access Journals (Sweden)

    Agrawal Amit

    2015-03-01

    Full Text Available Pneumocephalus can develop immediately following head trauma or clinical presentation may be delayed for days. We report a case of 35 year male whose initial CT scan brain plain small specks of pneumocephalus in left para-sellar region. However the next day he was complaining of severe headache and had multiple episodes of vomiting. Repeat CT scan showed increase in the size of pneumocephalus including appearance of intraventricular air with mild cerebral edema. The patient recovered well with conservative management. The present case is a gentle reminder that in a subgroup of head injury patients, intracranial air can produce significant mass effect leading to tension pneumocephalus which can can behave like other intracranial mass lesions and causes worsening of the neurological status of these patients.

  9. Stabilizing model predictive control for constrained nonlinear distributed delay systems.

    Science.gov (United States)

    Mahboobi Esfanjani, R; Nikravesh, S K Y

    2011-04-01

    In this paper, a model predictive control scheme with guaranteed closed-loop asymptotic stability is proposed for a class of constrained nonlinear time-delay systems with discrete and distributed delays. A suitable terminal cost functional and also an appropriate terminal region are utilized to achieve asymptotic stability. To determine the terminal cost, a locally asymptotically stabilizing controller is designed and an appropriate Lyapunov-Krasoskii functional of the locally stabilized system is employed as the terminal cost. Furthermore, an invariant set for locally stabilized system which is established by using the Razumikhin Theorem is used as the terminal region. Simple conditions are derived to obtain terminal cost and terminal region in terms of Bilinear Matrix Inequalities. The method is illustrated by a numerical example.

  10. Delay-sensitive and delay-insensitive deconvolution perfusion-CT: similar ischemic core and penumbra volumes if appropriate threshold selected for each

    Energy Technology Data Exchange (ETDEWEB)

    Man, Fengyuan [Capital Medical University, Department of Radiology, Beijing Tongren Hospital, Beijing (China); University of Virginia, Department of Radiology, Neuroradiology Division, Charlottesville, VA (United States); Patrie, James T.; Xin, Wenjun [University of Virginia, Department of Public Health Sciences, Charlottesville, VA (United States); Zhu, Guangming [University of Virginia, Department of Radiology, Neuroradiology Division, Charlottesville, VA (United States); Military General Hospital of Beijing PLA, Department of Neurology, Beijing (China); Hou, Qinghua [University of Virginia, Department of Radiology, Neuroradiology Division, Charlottesville, VA (United States); The Second Affiliated Hospital of Guangzhou Medical University, Department of Neurology, Guangzhou (China); Michel, Patrik; Eskandari, Ashraf [Centre Hospitalier Universitaire Vaudois, Department of Neurology, Lausanne (Switzerland); Jovin, Tudor [University of Pittsburgh, Department of Neurology, Pittsburgh, PA (United States); Xian, Junfang; Wang, Zhenchang [Capital Medical University, Department of Radiology, Beijing Tongren Hospital, Beijing (China); Wintermark, Max [University of Virginia, Department of Radiology, Neuroradiology Division, Charlottesville, VA (United States); Centre Hospitalier Universitaire Vaudois, Department of Radiology, Lausanne (Switzerland); Stanford University, Department of Radiology, Neuroradiology Division, Stanford, CA (United States)

    2015-03-07

    Perfusion-CT (PCT) processing involves deconvolution, a mathematical operation that computes the perfusion parameters from the PCT time density curves and an arterial curve. Delay-sensitive deconvolution does not correct for arrival delay of contrast, whereas delay-insensitive deconvolution does. The goal of this study was to compare delay-sensitive and delay-insensitive deconvolution PCT in terms of delineation of the ischemic core and penumbra. We retrospectively identified 100 patients with acute ischemic stroke who underwent admission PCT and CT angiography (CTA), a follow-up vascular study to determine recanalization status, and a follow-up noncontrast head CT (NCT) or MRI to calculate final infarct volume. PCT datasets were processed twice, once using delay-sensitive deconvolution and once using delay-insensitive deconvolution. Regions of interest (ROIs) were drawn, and cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT) in these ROIs were recorded and compared. Volume and geographic distribution of ischemic core and penumbra using both deconvolution methods were also recorded and compared. MTT and CBF values are affected by the deconvolution method used (p < 0.05), while CBV values remain unchanged. Optimal thresholds to delineate ischemic core and penumbra are different for delay-sensitive (145 % MTT, CBV 2 ml x 100 g{sup -1} x min{sup -1}) and delay-insensitive deconvolution (135 % MTT, CBV 2 ml x 100 g{sup -1} x min{sup -1} for delay-insensitive deconvolution). When applying these different thresholds, however, the predicted ischemic core (p = 0.366) and penumbra (p = 0.405) were similar with both methods. Both delay-sensitive and delay-insensitive deconvolution methods are appropriate for PCT processing in acute ischemic stroke patients. The predicted ischemic core and penumbra are similar with both methods when using different sets of thresholds, specific for each deconvolution method. (orig.)

  11. Assembly delay line pulse generators

    CERN Multimedia

    1971-01-01

    Assembly of six of the ten delay line pulse generators that will power the ten kicker magnet modules. One modulator part contains two pulse generators. Capacitors, inductances, and voltage dividers are in the oil tank on the left. Triggered high-pressure spark gap switches are on the platforms on the right. High voltage pulse cables to the kicker magnet emerge under the spark gaps. In the centre background are the assembled master gaps.

  12. Teriparatide Induced Delayed Persistent Hypercalcemia

    Directory of Open Access Journals (Sweden)

    Nirosshan Thiruchelvam

    2014-01-01

    Full Text Available Teriparatide, a recombinant PTH, is an anabolic treatment for osteoporosis that increases bone density. Transient hypercalcemia is a reported side effect of teriparatide that is seen few hours following administration of teriparatide and resolves usually within 16 hours of drug administration. Persistent hypercalcemia, although not observed in clinical trials, is rarely reported. The current case describes a rare complication of teriparatide induced delayed persistent hypercalcemia.

  13. Time delays across saddles as a test of modified gravity

    CERN Document Server

    Magueijo, Joao

    2012-01-01

    Modified gravity theories can produce strong signals in the vicinity of the saddles of the total gravitational potential. In a sub-class of these models this translates into diverging time-delays for echoes crossing the saddles. Such models arise from the possibility that gravity might be infrared divergent or confined, and if suitably designed they are very difficult to rule out. We show that Lunar Laser Ranging during an eclipse could probe the time-delay effect within meters of the saddle, thereby proving or excluding these models. Very Large Baseline Interferometry, instead, could target delays across the Jupiter-Sun saddle. Such experiments would shed light on the infrared behaviour of gravity and examine the puzzling possibility that there might be well-hidden regions of strong gravity and even singularities inside the solar system.

  14. Effect of exposure delay of concrete into aggressive environment

    Science.gov (United States)

    Abimouloud, Youcef; Kriker, Abdelouahed

    2016-07-01

    Some regions in the world suffered since several years from environmental problems such as underground level water rising. Water table effects durability of concrete implantation in the underground by the ease of luckless chemical elements ingress mainly through concrete the foundations of structures such as sulfate, chloride, and acids. For that reason a lot of foundations structures were made with SRPC (sulfate resisting Portland cement). This study is a contribution to assess the effect of exposure delay of concrete into aggressive fields, as a kind of cure which protects concrete from aggressive factors and allows it to acquire the needed strength. The study has shown that concrete exposure delay into aggressive environment is not a kind of cure mainly for concrete made with SRPC. Concrete with SRPC immediately exposed to aggressive environment shows a better mechanical resistance than concrete that has known exposure delay.

  15. A quantum delayed choice experiment

    CERN Document Server

    Peruzzo, Alberto; Brunner, Nicolas; Popescu, Sandu; O'Brien, Jeremy L

    2012-01-01

    Quantum systems exhibit particle-like or wave-like behaviour depending on the experimental apparatus they are confronted by. This wave-particle duality is at the heart of quantum mechanics, and is fully captured in Wheeler's famous delayed choice gedanken experiment. In this variant of the double slit experiment, the observer chooses to test either the particle or wave nature of a photon after it has passed through the slits. Here we report on a quantum delayed choice experiment, based on a quantum controlled beam-splitter, in which both particle and wave behaviours can be investigated simultaneously. The genuinely quantum nature of the photon's behaviour is tested via a Bell inequality, which here replaces the delayed choice of the observer. We observe strong Bell inequality violations, thus showing that no model in which the photon knows in advance what type of experiment it will be confronted by, hence behaving either as a particle or as wave, can account for the experimental data.

  16. Multiple μ-stability of neural networks with unbounded time-varying delays.

    Science.gov (United States)

    Wang, Lili; Chen, Tianping

    2014-05-01

    In this paper, we are concerned with a class of recurrent neural networks with unbounded time-varying delays. Based on the geometrical configuration of activation functions, the phase space R(n) can be divided into several Φη-type subsets. Accordingly, a new set of regions Ωη are proposed, and rigorous mathematical analysis is provided to derive the existence of equilibrium point and its local μ-stability in each Ωη. It concludes that the n-dimensional neural networks can exhibit at least 3(n) equilibrium points and 2(n) of them are μ-stable. Furthermore, due to the compatible property, a set of new conditions are presented to address the dynamics in the remaining 3(n)-2(n) subset regions. As direct applications of these results, we can get some criteria on the multiple exponential stability, multiple power stability, multiple log-stability, multiple log-log-stability and so on. In addition, the approach and results can also be extended to the neural networks with K-level nonlinear activation functions and unbounded time-varying delays, in which there can store (2K+1)(n) equilibrium points, (K+1)(n) of them are locally μ-stable. Numerical examples are given to illustrate the effectiveness of our results.

  17. Delay-induced instabilities in self-propelling swarms

    OpenAIRE

    Forgoston, Eric; Schwartz, Ira B.

    2008-01-01

    We consider a general model of self-propelling particles interacting through a pairwise attractive force in the presence of noise and communication time delay. Previous work by Erdmann, et al. [Phys. Rev. E {\\bf 71}, 051904 (2205)] has shown that a large enough noise intensity will cause a translating swarm of individuals to transition to a rotating swarm with a stationary center of mass. We show that with the addition of a time delay, the model possesses a transition that depends on the size...

  18. Reconfigurable diplexer based on switched delay line approach

    DEFF Research Database (Denmark)

    Zhurbenko, Vitaliy; Acar, Öncel; Ruaro, Andrea;

    2013-01-01

    In this work, a concept for the realization of a reconfigurable microwave multiplexer based on a switched delay-line topology is presented. The multiplexing concept is studied by considering a diplexer example. The topology provides two times reduction in the number of filters in comparison to the...... conventional directional filter approach. The switched delay-line topology enables the lossy and nonlinear switching elements to be used as a part of the coupling elements rather than within the resonators. Therefore, the diplexer potentially allows for a low insertion loss and high linearity. In addition...

  19. On Hamlet's Delay in the Revenge

    Institute of Scientific and Technical Information of China (English)

    刘莎

    2009-01-01

    Hamlet is a representative tragedy written by Shakespeare. Question on Hemlet's delay has been drawing the interest of many literature critics. It is still under discussion today. This thesis focuses on analyzing the reasons for Hamlet's delay in the revenge.

  20. Delaying or Preventing Type 2 Diabetes

    Science.gov (United States)

    ... Care Diabetes Statistics Delaying or Preventing Type 2 Diabetes What is type 2 diabetes? Type 2 diabetes, formerly called adult-onset diabetes, ... for some, taking aspirin daily. Can type 2 diabetes be delayed or prevented? Yes. The results of ...

  1. Chimera states in purely local delay-coupled oscillators

    Science.gov (United States)

    Bera, Bidesh K.; Ghosh, Dibakar

    2016-05-01

    We study the existence of chimera states in a network of locally coupled chaotic and limit-cycle oscillators. The necessary condition for chimera state in purely local coupled oscillators is discussed. At first, we numerically observe the existence of chimera or multichimera states in the locally coupled Hindmarsh-Rose neuron model. We find that delay time in the nonlinear local coupling reduces the domain of the coherent island in the parameter space of the synaptic coupling strength and time delay, and thus the coherent region can be completely eliminated once the time delay exceeds a certain threshold. We then consider another form of nonlinearity in the local coupling, and the existence of chimera states is observed in the time-delayed Mackey-Glass system and in a Van der Pol oscillator. We also discuss the effect of time delay in local coupling for the existence of chimera states in Mackey-Glass systems. The nonlinearity present in the coupling function plays a key role in the emergence of chimera or multichimera states. A phase diagram for the chimera state is identified over a wide parameter space.

  2. Data Mining for Understanding and Impriving Decision-Making Affecting Ground Delay Programs

    Science.gov (United States)

    Kulkarni, Deepak; Wang, Yao Xun; Sridhar, Banavar

    2013-01-01

    The continuous growth in the demand for air transportation results in an imbalance between airspace capacity and traffic demand. The airspace capacity of a region depends on the ability of the system to maintain safe separation between aircraft in the region. In addition to growing demand, the airspace capacity is severely limited by convective weather. During such conditions, traffic managers at the FAA's Air Traffic Control System Command Center (ATCSCC) and dispatchers at various Airlines' Operations Center (AOC) collaborate to mitigate the demand-capacity imbalance caused by weather. The end result is the implementation of a set of Traffic Flow Management (TFM) initiatives such as ground delay programs, reroute advisories, flow metering, and ground stops. Data Mining is the automated process of analyzing large sets of data and then extracting patterns in the data. Data mining tools are capable of predicting behaviors and future trends, allowing an organization to benefit from past experience in making knowledge-driven decisions. The work reported in this paper is focused on ground delay programs. Data mining algorithms have the potential to develop associations between weather patterns and the corresponding ground delay program responses. If successful, they can be used to improve and standardize TFM decision resulting in better predictability of traffic flows on days with reliable weather forecasts. The approach here seeks to develop a set of data mining and machine learning models and apply them to historical archives of weather observations and forecasts and TFM initiatives to determine the extent to which the theory can predict and explain the observed traffic flow behaviors.

  3. Indigenous mothers face more than three delays: The challenges of multiculturalism in health

    Directory of Open Access Journals (Sweden)

    Roosta-G., Manigeh

    2015-08-01

    Full Text Available Although the maternal mortality ratio has descended in Bolivia from 416 (1989 to 229 deaths (DHS 2003 per one hundred thousand live births, it is one of the highest in the region. As a national average, the ratio conceals the rural-urban, socio-economics differences and the reality of the indigenous population. Maternal mortality is one of the major challenges at national level. Reduction of maternal mortality, in addition of technical-medical measures offering health services, requires to focus on socio-cultural aspects that hamper the access to health services. This article examines challenges faced by indigenous mothers accessing the health services. In addition to the geographic, economic and administrative barriers that generate delays in access to the health services, there are others that are presented in the context of multiculturalism resulting from discriminatory attitudes exercised in health centers. The testimonies of indigenous mothers show delays faced in health centers because of prejudice and discrimination suffered, threatening the lives of mothers and their babies. The study also suggests the need to deepen the concept of multiculturalism as a successful strategy in health, in order to promote equity and social justice on the horizon of more inclusive societies.

  4. Absolute stability of nonlinear systems with time delays and applications to neural networks

    Directory of Open Access Journals (Sweden)

    Xinzhi Liu

    2001-01-01

    Full Text Available In this paper, absolute stability of nonlinear systems with time delays is investigated. Sufficient conditions on absolute stability are derived by using the comparison principle and differential inequalities. These conditions are simple and easy to check. In addition, exponential stability conditions for some special cases of nonlinear delay systems are discussed. Applications of those results to cellular neural networks are presented.

  5. Modelling delay propagation within an airport network

    NARCIS (Netherlands)

    Pyrgiotis, N.; Malone, K.M.; Odoni, A.

    2013-01-01

    We describe an analytical queuing and network decomposition model developed to study the complex phenomenon of the propagation of delays within a large network of major airports. The Approximate Network Delays (AND) model computes the delays due to local congestion at individual airports and capture

  6. Nonautonomous Lotka-Volterra Systems with Delays

    Science.gov (United States)

    Teng, Zhidong

    2002-03-01

    The paper studies the general nonautonomous Lotka-Volterra multispecies systems with finite delays. The ultimate boundedness, permanence, global attractivity, and existence and uniqueness of strictly positive solutions, positive periodic solutions, and almost periodic solutions are obtained. These results are basically an extension of the known results for nonautonomous Lotka-Volterra multispecies systems without delay to systems with delay.

  7. Synchronization analysis of coloured delayed networks under decentralized pinning intermittent control

    Indian Academy of Sciences (India)

    JIANG SHENGQIN; LU XIAOBO

    2016-06-01

    This paper investigates synchronization of coloured delayed networks under decentralized pinning intermittent control. To begin with, the time delays are taken into account in the coloured networks. In addition, we propose a decentralized pinning intermittent control for coloured delayed networks, which is different from that most of pinning intermittent controls are only appliedto the nodes from 1 to l or centralized nodes. Moreover, sufficient conditions are derived to guarantee the synchronization of coloured delayed networks based on Lyapunov stability theorem. Finally, numerical simulations are provided to verify the validity of the obtained results.

  8. Stimulus Frequency Otoacoustic Emission Delays and Generating Mechanisms in Guinea Pigs, Chinchillas, and Simulations.

    Science.gov (United States)

    Berezina-Greene, Maria A; Guinan, John J

    2015-12-01

    According to coherent reflection theory (CRT), stimulus frequency otoacoustic emissions (SFOAEs) arise from cochlear irregularities coherently reflecting energy from basilar membrane motion within the traveling-wave peak. This reflected energy arrives in the ear canal predominantly with a single delay at each frequency. However, data from humans and animals indicate that (1) SFOAEs can have multiple delay components, (2) low-frequency SFOAE delays are too short to be accounted for by CRT, and (3) "SFOAEs" obtained with a 2nd ("suppressor") tone ≥2 octaves above the probe tone have been interpreted as arising from the area basal to the region of cochlear amplification. To explore these issues, we collected SFOAEs by the suppression method in guinea pigs and time-frequency analyzed these data, simulated SFOAEs, and published chinchilla SFOAEs. Time-frequency analysis revealed that most frequencies showed only one SFOAE delay component while other frequencies had multiple components including some with short delays. We found no systematic patterns in the occurrence of multiple delay components. Using a cochlear model that had significant basilar membrane motion only in the peak region of the traveling wave, simulated SFOAEs had single and multiple delay components similar to the animal SFOAEs. This result indicates that multiple components (including ones with short delays) can originate from cochlear mechanical irregularities in the SFOAE peak region and are not necessarily indicative of SFOAE sources in regions ≥2 octaves basal of the SFOAE peak region. We conclude that SFOAEs obtained with suppressors close to the probe frequency provide information primarily about the mechanical response in the region that receives amplification, and we attribute the too-short SFOAE delays at low frequencies to distortion-source SFOAEs and coherent reflection from multiple cochlear motions. Our findings suggest that CRT needs revision to include reflections from multiple

  9. Epidemiology, diagnostic delay and outcome of tuberculosis in North Jutland, Denmark

    DEFF Research Database (Denmark)

    Andersen, Lene Rosa-Marie; Bjørn-Præst, Simon O; Gradel, Kim O;

    2011-01-01

    The objective of this study was to evaluate the clinical outcome of tuberculosis (TB) with regards to epidemiology, symptoms, delay, diagnostics, use of HIV-test, treatment, treatment outcome and mortality in the North Jutland Region from 2000 through 2008.......The objective of this study was to evaluate the clinical outcome of tuberculosis (TB) with regards to epidemiology, symptoms, delay, diagnostics, use of HIV-test, treatment, treatment outcome and mortality in the North Jutland Region from 2000 through 2008....

  10. Delay induced instabilities in self-propelling swarming particles

    Science.gov (United States)

    Forgoston, Eric; Schwartz, Ira

    2008-03-01

    We consider a general model of self-propelling biological or artificial individuals interacting through a pairwise attractive force in a two-dimensional system in the presence of noise and communication time delay. Previous work has shown that a large enough noise intensity will cause a translating swarm of individuals to transition to a rotating swarm with a stationary center of mass. In this work, we use numerical simulations to show that with the addition of a time delay, the model possesses a transition that depends on the size of the coupling parameter. This transition is independent of the swarm state (traveling or rotating) and is characterized by the alignment of all of the individuals along with a swarm oscillation. By considering the mean field equations without noise, we show that the time delay induced transition is associated with a Hopf bifurcation. The analytical result yields good agreement with numerical computations of the value of the coupling parameter at the Hopf point.

  11. Delay-induced instabilities in self-propelling swarms

    Science.gov (United States)

    Forgoston, Eric; Schwartz, Ira B.

    2008-03-01

    We consider a general model of self-propelling particles interacting through a pairwise attractive force in the presence of noise and communication time delay. Previous work by Erdmann [Phys. Rev. E 71, 051904 (2005)] has shown that a large enough noise intensity will cause a translating swarm of individuals to transition to a rotating swarm with a stationary center of mass. We show that with the addition of a time delay, the model possesses a transition that depends on the size of the coupling amplitude. This transition is independent of the initial swarm state (traveling or rotating) and is characterized by the alignment of all of the individuals along with a swarm oscillation. By considering the mean field equations without noise, we show that the time-delay-induced transition is associated with a Hopf bifurcation. The analytical result yields good agreement with numerical computations of the value of the coupling parameter at the Hopf point.

  12. A High Resolution On-Chip Delay Sensor with Low Supply-Voltage Sensitivity for High-Performance Electronic Systems

    Directory of Open Access Journals (Sweden)

    Duo Sheng

    2015-02-01

    Full Text Available An all-digital on-chip delay sensor (OCDS circuit with high delay-measurement resolution and low supply-voltage sensitivity for efficient detection and diagnosis in high-performance electronic system applications is presented. Based on the proposed delay measurement scheme, the quantization resolution of the proposed OCDS can be reduced to several picoseconds. Additionally, the proposed cascade-stage delay measurement circuit can enhance immunity to supply-voltage variations of the delay measurement resolution without extra self-biasing or calibration circuits. Simulation results show that the delay measurement resolution can be improved to 1.2 ps; the average delay resolution variation is 0.55% with supply-voltage variations of ±10%. Moreover, the proposed delay sensor can be implemented in an all-digital manner, making it very suitable for high-performance electronic system applications as well as system-level integration.

  13. Leapfrog: Optimal opportunistic Routing in Probabilistically Contacted Delay Tolerant Networks

    Institute of Scientific and Technical Information of China (English)

    Ming-Jun Xiao; Liu-Sheng Huang; Qun-Feng Dong; An Liu; Zhen-Guo Yang

    2009-01-01

    Delay tolerant networks (DTNs)experience frequent and long lasting network disconnection due to various reasons such as mobility.power management.and scheduling.One primary concern in DTNs is to route messages to keep the end-to-end delivery delay as low as possible.In this paper,we study the single-copy message routing problem and propose an optimal opportunistic routing strategy--Leapfrog Routing--for probabilistically contacted DTNs where nodes encounter or contact in some fixed probabilities.We deduce the iterative computation formulate of minimum expected opportunistic delivery delay from each node to the destination and discover that under the optimal opportunistic routing strategy,messages would be delivered from high-delay node to low-delay node in the leapfrog manner.Rigorous theoretical analysis shows that such a routing strategy is exactly the optimal among all possible ones.Moreover,we apply the idea of Reverse Dijkstra algorithm to design an algorithm.When a destination iS given,this algorithm can determine for each node the routing selection function under the Leapfrog Routing strategy.The computation overhead of this algorithm is only O(n~2) where n is the number of nodes in the network.In addition,through extensive simulations based on real DTN traces,we demonstrate that our algorithm can significantly outperform the previous ones.

  14. Clarifying the relationship between impulsive delay discounting and nicotine dependence.

    Science.gov (United States)

    Amlung, Michael; MacKillop, James

    2014-09-01

    Impulsive delayed reward discounting (DRD) has been linked to nicotine dependence, but with some inconsistency. This may be related to the considerable variability in the literature with regard to the DRD assessments used, particularly in the case of the reward magnitudes assessed. In addition, previous studies have often not considered concurrent substance use when examining the relationship between DRD and nicotine dependence. The current study sought to further clarify the relationship between DRD and nicotine dependence by characterizing DRD across diverse reward magnitudes and incorporating other substance use. Daily smokers (N = 933) were assessed for DRD preferences across nine reward magnitudes (delayed reward range: $2.50-$850), comorbid substance use, and relevant demographic variables (age, education, income). A significant large effect size magnitude effect was found for DRD, reflecting steeper discounting for smaller delayed rewards, but significant correlations across magnitudes also suggested similar relative levels of discounting. Principal components analysis (PCA) was used to generate a single latent index of discounting across all magnitudes that accounted for 69% of the total variance. In correlation and regression analyses, steeper composite DRD was significantly associated with nicotine dependence severity. This relationship remained statistically significant after incorporating demographic variables and alcohol and illicit drug use. These findings provide evidence of a specific link between impulsive DRD and nicotine dependence and reveal that this association is robust across a broad range of monetary rewards. The study also demonstrates the utility of using PCA to generate latent indices of delay discounting across multiple magnitudes of delayed reward. PMID:24841186

  15. Multi-agent consensus with time-varying delays and switching topologies

    Institute of Scientific and Technical Information of China (English)

    Jia Wei; and Huajing Fang

    2014-01-01

    The consensus problems of multi-agents with time-varying delays and switching topologies are studied. First, assume that an agent receives state information from its neighbors with fixed communication delays and processes its own state informa-tion with time-varying self-delay respectively. The state time-delay feedback is introduced into the existing consensus protocol to begenerate an improved protocol. Then a sufficient condition is derived which can make the system with time-varying self-delays achieve the consensus. On this basis, a specific form of consen-sus equilibrium influenced by the initial states of agents, time-delays and state feedback intensity is figured out. In addition, the multi-agent consensus is considered with time-varying topologies. Final y, simulations are presented to il ustrate the validity of theo-retical results.

  16. Delay-enhanced coherence of spiral waves in noisy Hodgkin-Huxley neuronal networks

    Energy Technology Data Exchange (ETDEWEB)

    Wang Qingyun [State Key Laboratory for Turbulence and Complex Systems, Department of Mechanics and Aerospace Engineering, College of Engineering, Peking University, Beijing 100871 (China) and School of Statistics and Mathematics, Inner Mongolia Finance and Economics College, Huhhot 010051 (China)], E-mail: nmqingyun@163.com; Perc, Matjaz [Department of Physics, Faculty of Natural Sciences and Mathematics, University of Maribor, Koroska cesta 160, SI-2000 Maribor (Slovenia); Duan Zhisheng [State Key Laboratory for Turbulence and Complex Systems, Department of Mechanics and Aerospace Engineering, College of Engineering, Peking University, Beijing 100871 (China); Chen Guanrong [State Key Laboratory for Turbulence and Complex Systems, Department of Mechanics and Aerospace Engineering, College of Engineering, Peking University, Beijing 100871 (China); Department of Electronic Engineering, City University of Hong Kong, Hong Kong (China)

    2008-08-25

    We study the spatial dynamics of spiral waves in noisy Hodgkin-Huxley neuronal ensembles evoked by different information transmission delays and network topologies. In classical settings of coherence resonance the intensity of noise is fine-tuned so as to optimize the system's response. Here, we keep the noise intensity constant, and instead, vary the length of information transmission delay amongst coupled neurons. We show that there exists an intermediate transmission delay by which the spiral waves are optimally ordered, hence indicating the existence of delay-enhanced coherence of spatial dynamics in the examined system. Additionally, we examine the robustness of this phenomenon as the diffusive interaction topology changes towards the small-world type, and discover that shortcut links amongst distant neurons hinder the emergence of coherent spiral waves irrespective of transmission delay length. Presented results thus provide insights that could facilitate the understanding of information transmission delay on realistic neuronal networks.

  17. BOLD delay times using group delay in sickle cell disease

    Science.gov (United States)

    Coloigner, Julie; Vu, Chau; Bush, Adam; Borzage, Matt; Rajagopalan, Vidya; Lepore, Natasha; Wood, John

    2016-03-01

    Sickle cell disease (SCD) is an inherited blood disorder that effects red blood cells, which can lead to vasoocclusion, ischemia and infarct. This disease often results in neurological damage and strokes, leading to morbidity and mortality. Functional Magnetic Resonance Imaging (fMRI) is a non-invasive technique for measuring and mapping the brain activity. Blood Oxygenation Level-Dependent (BOLD) signals contain also information about the neurovascular coupling, vascular reactivity, oxygenation and blood propagation. Temporal relationship between BOLD fluctuations in different parts of the brain provides also a mean to investigate the blood delay information. We used the induced desaturation as a label to profile transit times through different brain areas, reflecting oxygen utilization of tissue. In this study, we aimed to compare blood flow propagation delay times between these patients and healthy subjects in areas vascularized by anterior, middle and posterior cerebral arteries. In a group comparison analysis with control subjects, BOLD changes in these areas were found to be almost simultaneous and shorter in the SCD patients, because of their increased brain blood flow. Secondly, the analysis of a patient with a stenosis on the anterior cerebral artery indicated that signal of the area vascularized by this artery lagged the MCA signal. These findings suggest that sickle cell disease causes blood propagation modifications, and that these changes could be used as a biomarker of vascular damage.

  18. Value of delayed [{sup 18}F]-FDG-PET for brain tumors detection; Interet de la TEP au [{sup 18}F]-FDG double phase avec acquisition tardive dans la detection des tumeurs cerebrales

    Energy Technology Data Exchange (ETDEWEB)

    Vermeere, V.; Burg, S. [Centre Eugene-Marquis, Service de Medecine Nucleaire, 35 - Rennes (France); Wager, M. [Centre Hospitalier Universitaire de Poitiers, Service de Medecine Nucleaire et Biophysique, 86 - Poitiers (France); Perdrisot, R. [Centre Hospitalier Universitaire de Poitiers, Service de Neurochirurgie, 86 - Poitiers (France)

    2007-05-15

    The value of FDG-PET remains controversial in the study of brain tumors because of the high FDG uptake in gray matter. The aim of this study was to evaluate the utility of {sup 18}FDG-PET delayed acquisitions in the distinction of brain tumors from the cortex. Thirty patients with cerebral tumors were included, 25 high-grade tumors and five low grade. Two FDG-PET acquisitions, early (1 h), and delayed (5 h). were performed. On the delayed images. two types of three-dimensional regions of interest (ROI) were drawn using a Bayesian segmentation based on a Poisson law, the lesion ROI, specific (LS) and total (LT), and the ROI of references, on the healthy hemi-cortex (SG) and on the healthy white matter (SB). These ROI were reported on the early images. The evolution of the visualization of the lesions was appreciated using a qualitative visual analysis and a ROI ratios analysis. On the delayed images, the visual and the ROI ratios analysis showed an improvement of the visualization of the hyper-metabolic specific lesions compared to the SG and the SB. There was also a contrast improvement between the hypo-metabolic specific lesions and the SG with the ROI ratios analysis. Conclusion: delayed acquisitions in FDG-PET improve the visualization of brain tumors from the cortex. Dual phase FDG-PET with delayed acquisition could constitute an additional tool in the management of brain tumors. (authors)

  19. Delay Variation Model with Two Service Queues

    Directory of Open Access Journals (Sweden)

    Filip Rezac

    2010-01-01

    Full Text Available Delay in VoIP technology is very unpleasant issue and therefore a voice packets prioritization must be ensured. To maintain the high call quality a maximum information delivery time from the sender to the recipient is set to 150 ms. This paper focuses on the design of a mathematical model of end-to-end delay of a VoIP connection, in particular on a delay variation. It describes all partial delay components and mechanisms, their generation, facilities and mathematical formulations. A new approach to the delay variation model is presented and its validation has been done by experimention.

  20. Time-delayed feedback in neurosystems

    OpenAIRE

    Schoell, E.; Hiller, G; Hoevel, P.; Dahlem, M. A.

    2008-01-01

    The influence of time delay in systems of two coupled excitable neurons is studied in the framework of the FitzHugh-Nagumo model. Time-delay can occur in the coupling between neurons or in a self-feedback loop. The stochastic synchronization of instantaneously coupled neurons under the influence of white noise can be deliberately controlled by local time-delayed feedback. By appropriate choice of the delay time synchronization can be either enhanced or suppressed. In delay-coupled neurons, an...

  1. Reactor shutdown delays medical procedures

    Science.gov (United States)

    Gwynne, Peter

    2008-01-01

    A longer-than-expected maintenance shutdown of the Canadian nuclear reactor that produces North America's entire supply of molybdenum-99 - from which the radioactive isotopes technetium-99 and iodine-131 are made - caused delays to the diagnosis and treatment of thousands of seriously ill patients last month. Technetium-99 is a key component of nuclear-medicine scans, while iodine-131 is used to treat cancer and other diseases of the thyroid. Production eventually resumed, but only after the Canadian government had overruled the Canadian Nuclear Safety Commission (CNSC), which was still concerned about the reactor's safety.

  2. Delay-Dependent Observers for Uncertain Nonlinear Time-Delay Systems

    Directory of Open Access Journals (Sweden)

    Dongmei Yan

    2013-05-01

    Full Text Available This paper is concerned with the observer design problem for a class of discrete-time uncertain nonlinear systems with time-varying delay. The nonlinearities are assumed to satisfy global Lipschitz conditions which appear in both the state and measurement equations. The uncertainties are assumed to be time-varying but norm-bounded. Two Luenberger-like observers are proposed. One is delay observer and the other is delay-free observer. The delay observer which has an internal time delay is applicable when the time delay is known. The delay-free observer which does not use delayed information is especially applicable when the time delay is not known explicitly. Delay-dependent conditions for the existences of these two observers are derived based on Lyapunpv functional approach. Based on these conditions, the observer gains are obtained using the cone complementarity linearization algorithm. Finally, a numerical example is given to illustrate the effectiveness of the proposed method.

  3. Asymptotic Delay Analysis for Cross-Layer Delay-Based Routing in Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    Philippe Jacquet

    2007-01-01

    Full Text Available This paper addresses the problem of the evaluation of the delay distribution via analytical means in IEEE 802.11 wireless ad hoc networks. We show that the asymptotic delay distribution can be expressed as a power law. Based on the latter result, we present a cross-layer delay estimation protocol and we derive new delay-distribution-based routing algorithms, which are well adapted to the QoS requirements of real-time multimedia applications. In fact, multimedia services are not sensitive to average delays, but rather to the asymptotic delay distributions. Indeed, video streaming applications drop frames when they are received beyond a delay threshold, determined by the buffer size. Although delay-distribution-based routing is an NP-hard problem, we show that it can be solved in polynomial time when the delay threshold is large, because of the asymptotic power law distribution of the link delays.

  4. Reasons for diagnostic delay in gynecological malignancies

    DEFF Research Database (Denmark)

    Vandborg, Mai Partridge; Christensen, René dePont Christensen; Kragstrup, Jakob;

    2011-01-01

    ) and The Danish Gynecological Cancer Database (DGCD). 161 women were included; ovarian cancer: 63, endometrial cancer: 50, cervical cancer: 34 and vulvar cancer: 14. Outcome measures were different delay types counted in days and the influence of four clinical important variables: Presence of alarm symptoms, age......Aim The primary aim of this study was to identify and describe different delay types in women with gynecologic cancer, and to analyze the relationship between diagnostic delay and a number of characteristics for patients, cancers and the health care system. Setting A cohort study of women newly...... (≤ or > 60 years), performance of gynecological examination by the GP and notification of cancer suspicion on first referral from GP’s on the diagnostic delay (short delay ≤90 days and long delay >90 days). Results Across cancer type a median total delay of 101 days was observed. The 10% of women...

  5. Delay in the diagnosis of cancer

    DEFF Research Database (Denmark)

    Hansen, Rikke Pilegaard

    components, long delays were experienced by the 4th quartile of patients. We found much variation in delay by cancer type. In Article 2 we report that male patients had a higher likelihood of long doctor delays than women when gender-specific cancers were excluded, but apart from this, gender did not predict...... delay. Female patients with a high household fortune experienced shorter doctor and system delays and well-educated male patients experienced shorter doctor delays than the less privileged patients. We therefore hypothesized the existence of social inequalities in the distribution of delay. Article 3....... It is concluded that the study design may, to some extent, have given rise to selection and information bias and a risk of confounding, which, however, was largely accounted for in the analyses. We found a wide generalizability, although differences in health care systems regarding financing, degree...

  6. Estimation of time delay by coherence analysis

    CERN Document Server

    Govindan, R B; Kopper, F; Claussen, J C; Deuschl, G

    2004-01-01

    Using coherence analysis (which is an extensively used method to study the correlations in frequency domain, between two simultaneously measured signals) we estimate the time delay between two signals. This method is suitable for time delay estimation of narrow band coherence signals for which the conventional methods cannot be reliably applied. We show by analysing coupled R\\"ossler attractors with a known delay, that the method yields satisfactory results. Then, we apply this method to human pathologic tremor. The delay between simultaneously measured traces of Electroencephalogram (EEG) and Electromyogram (EMG) data of subjects with essential hand tremor is calculated. We find that there is a delay of 11-27 milli-seconds ($ms$) between the tremor correlated parts (cortex) of the brain (EEG) and the trembling hand (EMG) which is in agreement with the experimentally observed delay value of 15 $ms$ for the cortico-muscular conduction time. By surrogate analysis we calculate error-bars of the estimated delay.

  7. Delay, Doppler, and amplitude characteristics of HF signals received over a 1300-km transauroral sky wave channel

    Science.gov (United States)

    Wagner, L. S.; Goldstein, J. A.; Rupar, M. A.; Kennedy, E. J.

    1995-05-01

    Channel probe observations of propagation conditions along a 1294-km transauroral path between Sondrestrom, Greenland, and Keflavik, Iceland, were made during the period from March 13 to April 2, 1992. The midpoint of this path was located at a corrected geomagnetic latitude of 72°. The objective of these measurements was to supplement the existing data base describing propagation conditions on the HF transauroral channel with data pertaining to a period around the time of solar maximum. Received signals for this path fell into three distinct groups depending on their amplitude and delay and Doppler spread characteristics. These are (1) strong, specularly reflected ionospheric returns characteristic of a quiescent daytime ionospheric channel during magnetically quiet conditions; (2) strong specular multipath signals reflected from horizontal gradients of electron density and regularly encountered at night; and (3) weak scatter returns that are also a persistent nighttime phenomenon. The scatter returns are usually observed at delays exceeding those anticipated for the one-hop return and, very often, at frequencies that are well above the MUF for the great circle propagation path. The multipath and scatter returns exhibit large delay and Doppler spreads indicative of spatially extensive distributions of drifting and randomly moving irregularities. Two measurement events are discussed which illustrate these conclusions: a noontime measurement with Kp = 3, and a midnight measurement with Kp = 2. The noontime measurement exhibited a scatter return from an isolated irregularity region in addition to the usual ionospheric reflected signals. A simple irregularity drift model produced delay and Doppler shift curves that were consistent with those observed for the scatter component of the received signal and supported a hypothesis of an irregularity region drift speed of 1200 m s-1 parallel to the great circle propagation path.

  8. Optimal Kalman Filtering for a Class of State Delay Systems with Randomly Multiple Sensor Delays

    OpenAIRE

    Dongyan Chen; Long Xu

    2014-01-01

    The optimal Kalman filtering problem is investigated for a class of discrete state delay stochastic systems with randomly multiple sensor delays. The phenomenon of measurement delay occurs in a random way and the delay rate for each sensor is described by a Bernoulli distributed random variable with known conditional probability. Based on the innovative analysis approach and recursive projection formula, a new linear optimal filter is designed such that, for the state delay and randomly multi...

  9. Synchronization of time-delay chaotic systems on small-world networks with delayed coupling

    Institute of Scientific and Technical Information of China (English)

    Qi Wei; Wang Ying-Hai

    2009-01-01

    By using the well-known Ikeda model as the node dynamics,this paper studies synchronization of time-delay systems on small-world networks where the connections between units involve time delays.It shows that,in contrast with the undelayed case,networks with delays can actually synchronize more easily.Specifically,for randomly distributed delays,time-delayed mutual coupling suppresses the chaotic behaviour by stabilizing a fixed point that is unstable for the uncoupled dynamical system.

  10. Design for Additive Manufacturing

    OpenAIRE

    Bertran Comellas, Martí

    2012-01-01

    This Thesis, Design for Additive Manufacturing, has been mainly focused on the design process and the considerations to be taken into account when designing parts for Additive Manufacturing. It starts with an introduction to Additive Manufacturing, the different technologies and processes are described to let the readers understand their operating principle, materials used and their strengths and weaknesses. The applications of Additive manufacturing are also explained in the introductory ...

  11. Can Large Time Delays Observed in Light Curves of Coronal Loops be Explained by Impulsive Heating?

    CERN Document Server

    Lionello, Roberto; Winebarger, Amy R; Linker, Jon A; Mikić, Zoran

    2015-01-01

    The light curves of solar coronal loops often peak first in channels associated with higher temperatures and then in those associated with lower. The time delays between the different narrowband EUV channels have been measured for many individual loops and recently for every pixel of an active region observation. Time delays between channels for an active region exhibit a wide range of values, with maxima $>$ 5,000\\,s. These large time delays make up 3-26\\% (depending on the channel pair) of the pixels where a significant, positive time delay is measured. It has been suggested that time delays can be explained by impulsive heating. In this paper, we investigate whether the largest observed time delays can be explained by this hypothesis by simulating a series of coronal loops with different heating rates, loop lengths, abundances, and geometries to determine the range of expected time delays between a set of four EUV channels. We find that impulsive heating cannot address the largest time delays observed in t...

  12. Fuzzy Association Degree with Delayed Time in Temporal Data Model

    Institute of Scientific and Technical Information of China (English)

    刘惟一; 郭陵芝; 宋宁

    2001-01-01

    This paper presents an expression of the semantic proximity. Based on the temporal data model, a method of the temporal approximation is given. Using these concepts, this paper provides an evaluated method of fuzzy and dynamic association degree with delayed time and a superposition method of association degrees. Particularly, by means of the fuzzy and dynamic association degree, the connection between the weather data of two regions can be discovered.

  13. Stability of Teleoperation Systems for Time-Varying Delays by Neutral LMI Techniques

    Directory of Open Access Journals (Sweden)

    Emma Delgado

    2012-01-01

    Full Text Available This paper investigates the delay-dependent stability of a teleoperation system based on the transparent Generalized Four-Channel control (G-4C scheme under time-varying communication delays. To address stability we choose here a primitive result providing a Linear Matrix Inequalities (LMIs approach based on Lyapunov-Krasovskii functionals. Firstly, the scheme is modeled as the neutral-type differential-delayed equation; that is, the delay affects not only the state but also the state derivative. Secondly, we apply a less conservative stability criteria based on LMIs that are delay dependent and delay's time-derivative dependent. The reason is that, for better performance in the case of small delays, we must accept the possibility that stability is lost for large delays. The approach is applied to an example, and its advantages are discussed. As a result, we propose to modify the values of standard controllers in G-4C defining the μ-4C scheme, which introduces a tuning factor μ to increase in practical conditions the stable region fixing the desired bounds on time-varying delay, with the particularity of maintaining the tracking properties provided by this transparent control scheme. The simulation results justify the proposed control architecture and confirm robust stability and performance.

  14. Measurement of subcriticality using delayed neutron source combined with pulsed neutron accelerator

    International Nuclear Information System (INIS)

    A new experimental method for subcriticality measurement was developed by using delayed neutron source which is produced by external pulsed neutron source to increase accuracy of measured results by overcoming the space dependency problem which means difference of measured results in different detector position and often appeared in almost all other subcriticality measurement techniques. Experiments were performed at Kyoto University Critical Assembly (KUCA) combined with a DT accelerator to produce pulsed neutron in outside of the core repeatedly. In this method, neutron detection counts in the prompt neutron time region which are appeared just after injection of pulsed neutron are omitted, whereas neutron counts in the delayed neutron time region which are appeared after disappearance of exponential decay of the prompt neutron are adopted in analysis based on neutron source multiplication method or neutron noise analysis method; the variance to mean ratio method. In the delayed neutron time region, neutron sources to initiate fission chain reactions in subcritical state are delayed neutrons from delayed neutron precursors which are mainly produced by fission chain reactions in the prompt neutron time region, and delayed neutron precursors exist only in the fuel region, which makes possible to decrease the space dependency problem. The obtained results were compared with conventional pulsed neutron method, and it was found that the space dependency problem in subcriticality measurement can be fairly decreased by using the present new method compared with conventional one. (author)

  15. Improved visualization of delayed perfusion in lung MRI

    Energy Technology Data Exchange (ETDEWEB)

    Risse, Frank [Department of Medical Physics in Radiology, German Cancer Research Center, Heidelberg (Germany); Eichinger, Monika [Department of Radiology, German Cancer Research Center, Heidelberg (Germany); Kauczor, Hans-Ulrich [Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg (Germany); Semmler, Wolfhard [Department of Medical Physics in Radiology, German Cancer Research Center, Heidelberg (Germany); Puderbach, Michael, E-mail: m.puderbach@dkfz.de [Department of Radiology, German Cancer Research Center, Heidelberg (Germany)

    2011-01-15

    Introduction: The investigation of pulmonary perfusion by three-dimensional (3D) dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) was proposed recently. Subtraction images are generated for clinical evaluation, but temporal information is lost and perfusion defects might therefore be masked in this process. The aim of this study is to demonstrate a simple analysis strategy and classification for 3D-DCE-MRI perfusion datasets in the lung without omitting the temporal information. Materials and methods: Pulmonary perfusion measurements were performed in patients with different lung diseases using a 1.5 T MR-scanner with a time-resolved 3D-GRE pulse sequence. 25 3D-volumes were acquired after iv-injection of 0.1 mmol/kg KG Gadolinium-DTPA. Three parameters were determined for each pixel: (1) peak enhancement S{sub n,max} normalized to the arterial input function to detect regions of reduced perfusion; (2) time between arterial peak enhancement in the large pulmonary artery and tissue peak enhancement {tau} to visualize regions with delayed bolus onset; and (3) ratio R = S{sub n,max}/{tau} was calculated to visualize impaired perfusion, irrespectively of whether related to reduced or delayed perfusion. Results: A manual selection of peak perfusion images is not required. Five different types of perfusion can be found: (1) normal perfusion; (2) delayed non-reduced perfusion; (3) reduced non-delayed perfusion; (4) reduced and delayed perfusion; and (5) no perfusion. Types II and IV could not be seen in subtraction images since the temporal information is necessary for this purpose. Conclusions: The analysis strategy in this study allows for a simple and observer-independent visualization and classification of impaired perfusion in dynamic contrast-enhanced pulmonary perfusion MRI by using the temporal information of the datasets.

  16. Cerebral white matter correlates of delay discounting in adolescents.

    Science.gov (United States)

    Ho, Beng-Choon; Koeppel, Julie A; Barry, Amy B

    2016-05-15

    The adolescent brain undergoes extensive structural white matter (WM) changes. Adolescence is also a critical time period during which cognitive, emotional and social maturation occurs in transition into adulthood. Compared to adults, adolescents are generally more impulsive with increased risk-taking behaviors. The goal of this study is to examine whether adolescent impulsivity may be related to cerebral WM maturation. In 89 healthy adolescents, we assessed impulsivity using the delay discounting task, and MRI WM volumes in brain regions previously implicated in delay discounting behaviors. We found that smaller delay discounting AUC (area under the curve) was associated with larger WM volumes in orbitofrontal, dorsolateral and medial prefrontal cortices (PFC) and motor cortex. There were no significant effects of AUC on WM volumes within somatosensory brain regions. In our sample, younger age was significantly associated with greater WM volumes in orbitofrontal and dorsolateral PFC subregions. Even after accounting for age-related effects, preference for immediate rewards (or greater impulsivity) still correlated with larger WM volumes in prefrontal regions known to mediate cognitive control. Our findings lend further support to the notion that reduced brain WM maturity may limit the ability in adolescents to forgo immediate rewards leading to greater impulsivity. PMID:26946275

  17. Conversion of linear time-invariant time-delay feedback systems into delay-differential equations with commensurate delays

    Science.gov (United States)

    Yamazaki, Tatsuya; Hagiwara, Tomomichi

    2014-08-01

    A new stability analysis method of time-delay systems (TDSs) called the monodromy operator approach has been studied under the assumption that a TDS is represented as a time-delay feedback system consisting of a finite-dimensional linear time-invariant (LTI) system and a pure delay. For applying this approach to TDSs described by delay-differential equations (DDEs), the problem of converting DDEs into representation as time-delay feedback systems has been studied. With regard to such a problem, it was shown that, under discontinuous initial functions, it is natural to define the solutions of DDEs in two different ways, and the above conversion problem was solved for each of these two definitions. More precisely, the solution of a DDE was represented as either the state of the finite-dimensional part of a time-delay feedback system or a part of the output of another time-delay feedback system, depending on which definition of the DDE solution one is talking about. Motivated by the importance in establishing a thorough relationship between time-delay feedback systems and DDEs, this paper discusses the opposite problem of converting time-delay feedback systems into representation as DDEs, including the discussions about the conversion of the initial conditions. We show that the state of (the finite-dimensional part of) a time-delay feedback system can be represented as the solution of a DDE in the sense of one of the two definitions, while its 'essential' output can be represented as that of another DDE in the sense of the other type of definition. Rigorously speaking, however, it is also shown that the latter representation is possible regardless of the initial conditions, while some initial condition could prevent the conversion into the former representation. This study hence establishes that the representation of TDSs as time-delay feedback systems possesses higher ability than that with DDEs, as description methods for LTI TDSs with commensurate delays.

  18. Mixed delay-independent/delay-dependent stability of uncertain linear time-delayed systems

    Institute of Scientific and Technical Information of China (English)

    LI Wenlin; DONG Rui

    2004-01-01

    @@ Consider uncertain linear time delay systems described by the following state equation: x(t)=[A0+Δ A0(t)]x(t)+∑ri=1[Ai+ΔAi(t)]x(t-τi).(1) x(t)=(t)t∈[-,0];=maxri=1{τi}(2) where Δ A0(*) and Δ Ai(*)(i=1,…,r) are real matrix functions.Δ Ai(t)=LiFi(t)Ei,ΔA0(t)=L0F0(t)E0, where Li,Ei are known real constant matrices and Fi(t) are unknown real time-varying matrices with Lebesgue measurable elements satisfying ‖Fi(t)‖I,t(i=0,1,…,r). In this note, we develop the methods of robust stability which is dependent on the size of some delays but independent on the size of the others and is based on the solution of linear matrix inequalities.

  19. Variable-delay feedback control of unstable steady states in retarded time-delayed systems

    CERN Document Server

    Gjurchinovski, Aleksandar; 10.1103/PhysRevE.81.016209

    2010-01-01

    We study the stability of unstable steady states in scalar retarded time-delayed systems subjected to a variable-delay feedback control. The important aspect of such a control problem is that time-delayed systems are already infinite-dimensional before the delayed feedback control is turned on. When the frequency of the modulation is large compared to the system's dynamics, the analytic approach consists of relating the stability properties of the resulting variable-delay system with those of an analogous distributed delay system. Otherwise, the stability domains are obtained by a numerical integration of the linearized variable-delay system. The analysis shows that the control domains are significantly larger than those in the usual time-delayed feedback control, and that the complexity of the domain structure depends on the form and the frequency of the delay modulation.

  20. Fuzzy delay model based fault simulator for crosstalk delay fault test generation in asynchronous sequential circuits

    Indian Academy of Sciences (India)

    S Jayanthy; M C Bhuvaneswari

    2015-02-01

    In this paper, a fuzzy delay model based crosstalk delay fault simulator is proposed. As design trends move towards nanometer technologies, more number of new parameters affects the delay of the component. Fuzzy delay models are ideal for modelling the uncertainty found in the design and manufacturing steps. The fault simulator based on fuzzy delay detects unstable states, oscillations and non-confluence of settling states in asynchronous sequential circuits. The fuzzy delay model based fault simulator is used to validate the test patterns produced by Elitist Non-dominated sorting Genetic Algorithm (ENGA) based test generator, for detecting crosstalk delay faults in asynchronous sequential circuits. The multi-objective genetic algorithm, ENGA targets two objectives of maximizing fault coverage and minimizing number of transitions. Experimental results are tabulated for SIS benchmark circuits for three gate delay models, namely unit delay model, rise/fall delay model and fuzzy delay model. Experimental results indicate that test validation using fuzzy delay model is more accurate than unit delay model and rise/fall delay model.

  1. Cell probing by delayed luminescence

    Science.gov (United States)

    Musumeci, Francesco; Ballerini, Monica; Baroni, Giuliana; Costato, Michele; Ferraro, Lorenzo; Milani, Marziale; Scordino, Agata; Triglia, Antonio

    1999-05-01

    Delayed luminescence (D.L.) is a measure that provides important information on biological systems fields, structures and activities, by counting impinging and emitted photons. Many recent experimental works have shown the existence of a close connection, sometimes analytically expressed between the biological state of the system and D.L. parameters. Our investigations aim to show that D.L. is a workable analytical technique covering a large number of disciplinary fields, from agriculture to pollution control and from medical diagnostics to food quality control. The authors have conducted systematic research about D.L. from unicellular alga Acetabularia acetabulum to Saccharomyces cerevisiae yeast cultures and about more complex systems such as Soya seed (Glycine max, L.) and its dependence on sample preparation, history, intracellular signaling, metabolism and pollutant presence. We will discuss the most relevant results together with theoretical considerations on the basic interaction at work between biological systems and electromagnetic fields.

  2. Delay Estimator and Improved Proportionate Multi-Delay Adaptive Filtering Algorithm

    Directory of Open Access Journals (Sweden)

    E. Verteletskaya

    2012-04-01

    Full Text Available This paper pertains to speech and acoustic signal processing, and particularly to a determination of echo path delay and operation of echo cancellers. To cancel long echoes, the number of weights in a conventional adaptive filter must be large. The length of the adaptive filter will directly affect both the degree of accuracy and the convergence speed of the adaptation process. We present a new adaptive structure which is capable to deal with multiple dispersive echo paths. An adaptive filter according to the present invention includes means for storing an impulse response in a memory, the impulse response being indicative of the characteristics of a transmission line. It also includes a delay estimator for detecting ranges of samples within the impulse response having relatively large distribution of echo energy. These ranges of samples are being indicative of echoes on the transmission line. An adaptive filter has a plurality of weighted taps, each of the weighted taps having an associated tap weight value. A tap allocation/control circuit establishes the tap weight values in response to said detecting means so that only taps within the regions of relatively large distributions of echo energy are turned on. Thus, the convergence speed and the degree of estimation in the adaptation process can be improved.

  3. Additives in yoghurt production

    Directory of Open Access Journals (Sweden)

    Milna Tudor

    2008-02-01

    Full Text Available In yoghurt production, mainly because of sensory characteristics, different types of additives are used. Each group, and also each substance from the same group has different characteristics and properties. For that reason, for improvement of yoghurt sensory characteristics apart from addition selection, the quantity of the additive is very important. The same substance added in optimal amount improves yoghurt sensory attributes, but too small or too big addition can reduce yoghurt sensory attributes. In this paper, characteristics and properties of mostly used additives in yoghurt production are described; skimmed milk powder, whey powder, concentrated whey powder, sugars and artificial sweeteners, fruits, stabilizers, casein powder, inulin and vitamins. Also the impact of each additive on sensory and physical properties of yoghurt, syneresis and viscosity, are described, depending on used amount added in yoghurt production.

  4. Dynamics of Nonlinear Time-Delay Systems

    CERN Document Server

    Lakshmanan, Muthusamy

    2010-01-01

    Synchronization of chaotic systems, a patently nonlinear phenomenon, has emerged as a highly active interdisciplinary research topic at the interface of physics, biology, applied mathematics and engineering sciences. In this connection, time-delay systems described by delay differential equations have developed as particularly suitable tools for modeling specific dynamical systems. Indeed, time-delay is ubiquitous in many physical systems, for example due to finite switching speeds of amplifiers in electronic circuits, finite lengths of vehicles in traffic flows, finite signal propagation times in biological networks and circuits, and quite generally whenever memory effects are relevant. This monograph presents the basics of chaotic time-delay systems and their synchronization with an emphasis on the effects of time-delay feedback which give rise to new collective dynamics. Special attention is devoted to scalar chaotic/hyperchaotic time-delay systems, and some higher order models, occurring in different bran...

  5. Phase changes in delay propagation networks

    CERN Document Server

    Belkoura, Seddik

    2016-01-01

    The analysis of the dynamics of delays propagation is one of the major topics inside Air Transport Management research. Delays are generated by the elements of the system, but their propagation is a global process fostered by relationships inside the network. If the topology of such propagation process has been extensively studied in the literature, little attention has been devoted to the fact that such topology may have a dynamical nature. Here we differentiate between two phases of the system by applying two causality metrics, respectively describing the standard phase (i.e. propagation of normal delays) and a disrupted one (corresponding to abnormal and unexpected delays). We identify the critical point triggering the change of the topology of the system, in terms of delays magnitude, using a historical data set of flights crossing Europe in 2011. We anticipate that the proposed results will open new doors towards the understanding of the delay propagation dynamics and the mitigation of extreme events.

  6. Delay banking for air traffic management

    Science.gov (United States)

    Green, Steven M. (Inventor)

    2007-01-01

    A method and associated system for time delay banking for aircraft arrival time, aircraft departure time and/or en route flight position. The delay credit value for a given flight may decrease with passage of time and may be transferred to or traded with other flights having the same or a different user (airline owner or operator). The delay credit value for a given aircraft flight depends upon an initial delay credit value, which is determined by a central system and depends upon one or more other flight characteristics. Optionally, the delay credit value decreases with passage of time. Optionally, a transaction cost is assessed against a delay credit value that is used on behalf of another flight with the same user or is traded with a different user.

  7. Wire + Arc Additive Manufacturing

    OpenAIRE

    Williams, Stewart W.; Martina, Filomeno; Addison, Adrian C.; Ding, Jialuo; Pardal, Goncalo; Colegrove, Paul A.

    2016-01-01

    Depositing large components (>10 kg) in titanium, aluminium, steel and other metals is possible using Wire + Arc Additive Manufacturing. This technology adopts arc welding tools and wire as feedstock for additive manufacturing purposes. High deposition rates, low material and equipment costs, and good structural integrity make Wire+Arc Additive Manufacturing a suitable candidate for replacing the current method of manufacturing from solid billets or large forgings, especially with regards to ...

  8. Vicarious Michael Addition

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    C-H bond can undergo vicarious Michael addition reaction (VMA) with doubleactivated double bond in the absence of strong base and catalyst under mild conditions.Intramolecular H-bonding, electron-withdrawing inductive effect, and steric hindrance at aposition of nucleophile facilitates C-H addition over N-H addition. By using VMA, high branching multiplicity, novel branching pattern, controllable density and distribution of functional groups can be envisioned for novel dendrimer synthesis.

  9. DELAYED FLOWERING, an Arabidopsis Gene That Acts in the Autonomous Flowering Promotion Pathway and Is Required for Normal Development

    Institute of Scientific and Technical Information of China (English)

    Ming-Jie Chen; Zheng Yuan; Hai Huang

    2006-01-01

    The control of flowering time in higher plants is one of the most important physiological processes and is critical for their reproductive success. To investigate the mechanisms controlling flowering time, we screened for Arabidopsis mutants with late-flowering phenotypes. One mutant, designated delayed flowering (dfr) in the Landsberg erecta (Ler) ecotype, was identified with delayed flowering time. Genetic analysis revealed that dfr is a single gene recessive nuclear mutant and the mutation was mapped to a locus tightly linked to UFO on chromosome 1. To our knowledge, no gene regulating flowering time has been reported yet in this region. The dfr mutant plant showed a delayed flowering time under the different growth conditions examined,including long- and short-day photoperiods and gibberellic acid GA3 treatments, suggesting that DFR is a gene involved in the autonomous flowering promotion pathway. The Arabidopsis gene FLOWERING LOCUS C (FLC) plays a central role in repressing flowering and its transcripts are undetectable in wild-type Ler.However, FLCexpression was upregulated in the dfrmutant, suggesting that DFR is a negative regulator of FLC. In addition, the dfr mutant plant displayed altered valve shapes of the silique and the number of trichomes and branches of each trichome were both reduced, indicating that the DRFgene is also required for normal plant development. Moreover, dfr leafy-5 (Ify-5) double mutant plants showed a much later flowering time than either dfr or Ify-5 single mutants, indicating that DFR and LFYact synergistically to promote flowering in Arabidopsis.

  10. Effects of Time Delay on the Bistable System Subjected to Correlated Noises

    Institute of Scientific and Technical Information of China (English)

    NIE Lin-Ru; Mei Dong-Cheng

    2007-01-01

    The time-delayed bistable system subjected to the multiplicative and additive noises is investigated. In the condition of small delay time, the stationary probability distribution function (SPDF) is derived, and under the condition of large delay time, the SPDF is stochastically simulated. The analytical and simulative results indicate that: (i) For the case of λ= 0λ denotes the strength of correlations between the multiplicative and additive noises), the time delay affects weakly the SPDF peak structure, and the symmetrical property of the SPDF two-peak structure does not change with the increasing delay time, (ii) For the case of λ≠0, the two-peak structure changes with the increasing delay time, i.e. one peak goes up and the other go down simultaneously as the delay time increases and along with further increase of the delay time, the lower peak disappears gradually while the higher one goes up, i.e. the structure of the SPDF changes from a bimodal to a unimodal and the system becomes monostable.

  11. Prehospital delay in acute coronary syndrome--an analysis of the components of delay

    DEFF Research Database (Denmark)

    Ottesen, Michael Mundt; Dixen, Ulrik; Torp-Pedersen, Christian;

    2004-01-01

    more frequently atypical symptoms and increased prehospital delay caused by prolonged physician and transportation delay. Physician delay among women and men were 69 and 16 min, respectively. Patients with prior myocardial infarction had reduced prehospital delay, which was caused by shorter decision...... admitted with acute coronary syndrome is warranted. METHODS: A structured interview was conducted on 250 consecutive patients admitted alive with acute coronary syndrome. RESULTS: Median prehospital, decision, physician and transportation delays were 107, 74, 25 and 22 min, respectively. Women (n=77) had...... of acute coronary syndrome among women, and thereby contributes to unnecessary long delay to treatment. The patient's prior experience and interpretation has a significant influence on behaviour....

  12. Additional disulfide bonds in insulin

    DEFF Research Database (Denmark)

    Vinther, Tine N; Pettersson, Ingrid; Huus, Kasper;

    2015-01-01

    The structure of insulin, a glucose homeostasis-controlling hormone, is highly conserved in all vertebrates and stabilized by three disulfide bonds. Recently, we designed a novel insulin analogue containing a fourth disulfide bond located between positions A10-B4. The N-terminus of insulin's B......-chain is flexible and can adapt multiple conformations. We examined how well disulfide bond predictions algorithms could identify disulfide bonds in this region of insulin. In order to identify stable insulin analogues with additional disulfide bonds, which could be expressed, the Cβ cut-off distance had...... in comparison to analogues with additional disulfide bonds that were more difficult to predict. In contrast, addition of the fourth disulfide bond rendered all analogues resistant to fibrillation under stress conditions and all stable analogues bound to the insulin receptor with picomolar affinities. Thus...

  13. Delayed Self-Synchronization in Homoclinic Chaos

    OpenAIRE

    Arecchi, F. T.; Meucci, R.; E. Allaria; Di Garbo, A.; Tsimring, L. S.

    2001-01-01

    The chaotic spike train of a homoclinic dynamical system is self-synchronized by re-inserting a small fraction of the delayed output. Due to the sensitive nature of the homoclinic chaos to external perturbations, stabilization of very long periodic orbits is possible. On these orbits, the dynamics appears chaotic over a finite time, but then it repeats with a recurrence time that is slightly longer than the delay time. The effect, called delayed self-synchronization (DSS), displays analogies ...

  14. Delay in camera-to-display systems

    OpenAIRE

    2011-01-01

    Today we see an increasing number of time dependent visual computer systems, ranging from interactive video installations, via high definition teleconferencing to the high performance computer vision disciplines for example in industry and robotics. Common for all of these are the requirement for low and predictable delays from the system itself and its components. In this thesis, we look into the delay of camera-to-display computer systems to understand the properties of their delay com...

  15. Bubbling in delay-coupled lasers

    OpenAIRE

    Flunkert, V.; D'Huys, O.; Danckaert, J.; Fischer, I.; Schoell, E.

    2009-01-01

    We theoretically study chaos synchronization of two lasers which are delay-coupled via an active or a passive relay. While the lasers are synchronized, their dynamics is identical to a single laser with delayed feedback for a passive relay and identical to two delay-coupled lasers for an active relay. Depending on the coupling parameters the system exhibits bubbling, i.e., noise-induced desynchronization, or on-off intermittency. We associate the desynchronization dynamics in the coherence co...

  16. Treatment of bronchial ruptures by delayed surgery

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    Objective:To study the causes that resulted in delayed surgery for bronchial ruptures and the results.Methods:The cases with the bronchial ruptures by the delayed surgery last decade were retrospectively reviewed.The causes and unsatisfactory results were analysed.Results:The severe complications usually occurred after the delayed surgery and the results were not as satisfactory as those by early surgery.Conclusion:The bronchial ruptures ought to be operated in the early stage after being wounded.

  17. Construction delay analysis of EDA Center building

    OpenAIRE

    Tomažič, Denis

    2011-01-01

    This theses deals with the analysis of building construction and timeline of the project using the delay calculation method. The first and the second part are devoted to building presentation and construction characteristic technology, diversification work phases, facility structure and technological work processes. The third and the fourth part presents in detail the method for calculating the delay based on various reasons, such as the delay that happened for not anchoring the tower cran...

  18. Group Delay of High Q Antennas

    DEFF Research Database (Denmark)

    Bahramzy, Pevand; Pedersen, Gert Frølund

    2013-01-01

    become an issue, when working with high Q antennas, because of the steep phase shift over the frequency. In this paper, it is measured how large group delay variations can become, when going from a low Q antenna to a high Q antenna. The group delay of a low Q antenna is shown to be around 1.3 ns, whereas...... a high Q antenna has group delay of around 22 ns. It is due to this huge group delay variation characteristics of high Q antennas, that signal distortion might occur in the radio system with high Q antennas....

  19. Reducing Transmitted Vibration Using Delayed Hysteretic Suspension

    Directory of Open Access Journals (Sweden)

    Lahcen Mokni

    2011-01-01

    Full Text Available Previous numerical and experimental works show that time delay technique is efficient to reduce transmissibility of vibration in a single pneumatic chamber by controlling the pressure in the chamber. The present work develops an analytical study to demonstrate the effectiveness of such a technique in reducing transmitted vibrations. A quarter-car model is considered and delayed hysteretic suspension is introduced in the system. Analytical predictions based on perturbation analysis show that a delayed hysteretic suspension enhances vibration isolation comparing to the case where the nonlinear damping is delay-independent.

  20. Angle-resolved time delay in photoemission

    CERN Document Server

    Wätzel, Jonas; Pavlyukh, Yaroslav; Berakdar, Jamal

    2014-01-01

    We investigate theoretically the relative time delay of photoelectrons originating from different atomic subshells of noble gases. This quantity was measured via attosecond streaking and studied theoretically by Schultze et al. [Science 328, 1658 (2010)] for neon. A substantial discrepancy was found between the measured and the calculated values of the relative time delay. Several theoretical studies were put forward to resolve this issue, e.g., by including correlation effects. In the present paper we explore a further aspect, namely the directional dependence of time delay. In contrast to neon, for argon target a strong angular dependence of time delay is found near a Cooper minimum.

  1. Synchronization of Delay-coupled Micromechanical Oscillators

    CERN Document Server

    Shah, Shreyas Y; Rand, Richard; Lipson, Michal

    2015-01-01

    Delay-coupled oscillators exhibit unique phenomena that are not present in systems without delayed coupling. In this paper, we experimentally demonstrate mutual synchronisation of two free-running micromechanical oscillators, coupled via light with a total delay 139 ns which is approximately four and a half times the mechanical oscillation time period. This coupling delay, imposed by a finite speed of propagation of light, induces multiple stable states of synchronised oscillations, each with a different oscillation frequency. These states can be accessed by varying the coupling strengths. Our result could enable applications in reconfigurable radio-frequency networks, and novel computing concepts.

  2. Time delay plots of unflavoured baryons

    Science.gov (United States)

    Kelkar, N. G.; Nowakowski, M.; Khemchandani, K. P.; Jain, S. R.

    2004-01-01

    We explore the usefulness of the existing relations between the S-matrix and time delay in characterizing baryon resonances in pion-nucleon scattering. We draw attention to the fact that the existence of a positive maximum in time delay is a necessary criterion for the existence of a resonance and should be used as a constraint in conventional analyses which locate resonances from poles of the S-matrix and Argand diagrams. The usefulness of the time delay plots of resonances is demonstrated through a detailed analysis of the time delay in several partial waves of πN elastic scattering.

  3. Delay Computation Using Fuzzy Logic Approach

    Directory of Open Access Journals (Sweden)

    Ramasesh G. R.

    2012-10-01

    Full Text Available The paper presents practical application of fuzzy sets and system theory in predicting delay, with reasonable accuracy, a wide range of factors pertaining to construction projects. In this paper we shall use fuzzy logic to predict delays on account of Delayed supplies and Labor shortage. It is observed that the project scheduling software use either deterministic method or probabilistic method for computation of schedule durations, delays, lags and other parameters. In other words, these methods use only quantitative inputs leaving-out the qualitative aspects associated with individual activity of work. The qualitative aspect viz., the expertise of the mason or the lack of experience can have a significant impact on the assessed duration. Such qualitative aspects do not find adequate representation in the Project Scheduling software. A realistic project is considered for which a PERT chart has been prepared using showing all the major activities in reasonable detail. This project has been periodically updated until its completion. It is observed that some of the activities are delayed due to extraneous factors resulting in the overall delay of the project. The software has the capability to calculate the overall delay through CPM (Critical Path Method when each of the activity-delays is reported. We shall now demonstrate that by using fuzzy logic, these delays could have been predicted well in advance.

  4. Does Braun Enteroenterostomy Reduce Delayed Gastric Emptying After Pancreaticoduodenectomy?

    OpenAIRE

    Zhang, Xu-Feng; Yin, Guo-Zhi; Liu, Qing-Guang; Liu, Xue-Min; Wang, Bo; Yu, Liang; Liu, Si-Nan; Cui, Hong-Ying; Lv, Yi

    2014-01-01

    Abstract Whether an additional Braun enteroenterostomy is necessary in reducing delayed gastric emptying (DGE) after pancreaticoduodenectomy (PD) has not yet been well investigated. Herein, in this retrospective study, 395 consecutive cases of patients undergoing classic PD from 2009 to 2013 were reviewed. Patients with and without Braun enteroenterostomy were compared in preoperative baseline characteristics, surgical procedure, postoperative diagnosis, and morbidity including DGE. The DGE w...

  5. Delay-range-dependent chaos synchronization approach under varying time-lags and delayed nonlinear coupling.

    Science.gov (United States)

    Zaheer, Muhammad Hamad; Rehan, Muhammad; Mustafa, Ghulam; Ashraf, Muhammad

    2014-11-01

    This paper proposes a novel state feedback delay-range-dependent control approach for chaos synchronization in coupled nonlinear time-delay systems. The coupling between two systems is esteemed to be nonlinear subject to time-lags. Time-varying nature of both the intrinsic and the coupling delays is incorporated to broad scope of the present study for a better-quality synchronization controller synthesis. Lyapunov-Krasovskii (LK) functional is employed to derive delay-range-dependent conditions that can be solved by means of the conventional linear matrix inequality (LMI)-tools. The resultant control approach for chaos synchronization of the master-slave time-delay systems considers non-zero lower bound of the intrinsic as well as the coupling time-delays. Further, the delay-dependent synchronization condition has been established as a special case of the proposed LK functional treatment. Furthermore, a delay-range-dependent condition, independent of the delay-rate, has been provided to address the situation when upper bound of the delay-derivative is unknown. A robust state feedback control methodology is formulated for synchronization of the time-delay chaotic networks against the L2 norm bounded perturbations by minimizing the L2 gain from the disturbance to the synchronization error. Numerical simulation results are provided for the time-delay chaotic networks to show effectiveness of the proposed delay-range-dependent chaos synchronization methodologies.

  6. Additive Gaussian Processes

    CERN Document Server

    Duvenaud, David; Rasmussen, Carl Edward

    2011-01-01

    We introduce a Gaussian process model of functions which are additive. An additive function is one which decomposes into a sum of low-dimensional functions, each depending on only a subset of the input variables. Additive GPs generalize both Generalized Additive Models, and the standard GP models which use squared-exponential kernels. Hyperparameter learning in this model can be seen as Bayesian Hierarchical Kernel Learning (HKL). We introduce an expressive but tractable parameterization of the kernel function, which allows efficient evaluation of all input interaction terms, whose number is exponential in the input dimension. The additional structure discoverable by this model results in increased interpretability, as well as state-of-the-art predictive power in regression tasks.

  7. Stochastic Resonance in a Gene Transcriptional Regulatory System with Time Delay

    Institute of Scientific and Technical Information of China (English)

    ZENG Chun-Hua; XIE Chong-Wei

    2008-01-01

    We study the stochastic resonance (SR) phenomenon in a time-delayed gene transcriptional regulatory system under the simultaneous action of a multiplicative noise and an additive noise and a weak periodic signal.The expression of the signal-to-noise ratio RSNR is obtained by applying the two-state theory in adiabatic limit under the condition of small delay time.The effects of delay time and intensity of the correlation between multiplicative and additive noise on RSNR are discussed.It is found that the delay time (T) enhances the SR of the system.The correlation intensity λ enhances the SR in the RSNR - D plot (D denotes the multiplicative noise intensity),but weakens the SR in the RSNR - α plot (α denotes the additive noise intensity).

  8. Stability of Nonlinear Systems with Unknown Time-varying Feedback Delay

    Science.gov (United States)

    Chunodkar, Apurva A.; Akella, Maruthi R.

    2013-12-01

    This paper considers the problem of stabilizing a class of nonlinear systems with unknown bounded delayed feedback wherein the time-varying delay is 1) piecewise constant 2) continuous with a bounded rate. We also consider application of these results to the stabilization of rigid-body attitude dynamics. In the first case, the time-delay in feedback is modeled specifically as a switch among an arbitrarily large set of unknown constant values with a known strict upper bound. The feedback is a linear function of the delayed states. In the case of linear systems with switched delay feedback, a new sufficiency condition for average dwell time result is presented using a complete type Lyapunov-Krasovskii (L-K) functional approach. Further, the corresponding switched system with nonlinear perturbations is proven to be exponentially stable inside a well characterized region of attraction for an appropriately chosen average dwell time. In the second case, the concept of the complete type L-K functional is extended to a class of nonlinear time-delay systems with unknown time-varying time-delay. This extension ensures stability robustness to time-delay in the control design for all values of time-delay less than the known upper bound. Model-transformation is used in order to partition the nonlinear system into a nominal linear part that is exponentially stable with a bounded perturbation. We obtain sufficient conditions which ensure exponential stability inside a region of attraction estimate. A constructive method to evaluate the sufficient conditions is presented together with comparison with the corresponding constant and piecewise constant delay. Numerical simulations are performed to illustrate the theoretical results of this paper.

  9. Can the Swedish new variant of Chlamydia trachomatis (nvCT) be detected by UK NEQAS participants from seventeen European countries and five additional countries/regions in 2009?

    Science.gov (United States)

    Unemo, M; Rossouw, A; James, V; Jenkins, C

    2009-05-14

    In 2006, a new variant of Chlamydia trachomatis (nvCT) was reported in Sweden. The nvCT contains a deletion that includes the targets for the C. trachomatis genetic diagnostic single-target systems from Roche Diagnostics and Abbott Laboratories. Roche and Abbott have now developed certified dual-target assays that can detect the nvCT. This study examined the nucleic acid amplification tests (NAATs) currently used (in 2009) for C. trachomatis detection in laboratories from 17 European countries and five countries/regions outside Europe that are participating in the United Kingdom (UK) National External Quality Assessment Service (NEQAS). It further examined changes in these laboratories' testing strategy during the period from 2006 to 2009, and their performance regarding nvCT detection. A UK NEQAS blinded nvCT specimen was distributed to all 283 participating laboratories, which were asked to analyse the specimen according to their routine C. trachomatis diagnostic protocols for endocervical swabs. BD ProbeTec was the most commonly used NAAT, followed by Cobas Amplicor, Cobas TaqMan, and Aptima. From 2006 to 2009, the use of Cobas Amplicor, which does not detect the nvCT, decreased, but it was still used by 22% (n=57) of responding participants in 59% of the countries, 54 of these 57 used it as first assay. Virtually all of the other participants detected the nvCT correctly. Laboratories using commercial or in house NAATs that do not detect the nvCT are encouraged to carefully monitor their C. trachomatis incidence, participate in effective internal and external quality assurance and controls schemes, and to consider changing their testing system. PMID:19442398

  10. A Novel Message Scheduling Framework for Delay Tolerant Networks Routing

    KAUST Repository

    Elwhishi, Ahmed

    2013-05-01

    Multicopy routing strategies have been considered the most applicable approaches to achieve message delivery in Delay Tolerant Networks (DTNs). Epidemic routing and two-hop forwarding routing are two well-reported approaches for delay tolerant networks routing which allow multiple message replicas to be launched in order to increase message delivery ratio and/or reduce message delivery delay. This advantage, nonetheless, is at the expense of additional buffer space and bandwidth overhead. Thus, to achieve efficient utilization of network resources, it is important to come up with an effective message scheduling strategy to determine which messages should be forwarded and which should be dropped in case of buffer is full. This paper investigates a new message scheduling framework for epidemic and two-hop forwarding routing in DTNs, such that the forwarding/dropping decision can be made at a node during each contact for either optimal message delivery ratio or message delivery delay. Extensive simulation results show that the proposed message scheduling framework can achieve better performance than its counterparts.

  11. Slow light in ruby: delaying energy beyond the input pulse

    Science.gov (United States)

    Wisniewski-Barker, Emma; Gibson, Graham; Franke-Arnold, Sonja; Shi, Zhimin; Narum, Paul; Boyd, Robert W.; Padgett, Miles J.

    2015-03-01

    The mechanism by which light is slowed through ruby has been the subject of great debate. To distinguish between the two main proposed mechanisms, we investigate the problem in the time domain by modulating a laser beam with a chopper to create a clean square wave. By exploring the trailing edge of the pulsed laser beam propagating through ruby, we can determine whether energy is delayed beyond the input pulse. The effects of a time-varying absorber alone cannot delay energy into the trailing edge of the pulse, as a time-varying absorber can only attenuate a coherent pulse. Therefore, our observation of an increase in intensity at the trailing edge of the pulse provides evidence for a complicated model of slow light in ruby that requires more than just pulse reshaping. In addition, investigating the Fourier components of the modulated square wave shows that harmonic components with different frequencies are delayed by different amounts, regardless of the intensity of the component itself. Understanding the difference in delays of the individual Fourier components of the modulated beam reveals the cause of the distortion the pulse undergoes as it propagates through the ruby.

  12. Delayed ventricular repolarization as an anti-arrhythmic principle.

    Science.gov (United States)

    Vaughan Williams, E M

    1985-11-01

    Depolarization of cardiac muscle is achieved by 'fast inward current' through channels which are inactivated within about 1 ms. When the cells are repolarized the process of inactivation of fast channels is rapidly reversed. The class 1 anti-arrhythmic drugs delay the disappearance of inactivation until long after repolarization is complete. In theory, it should be possible to produce a similar extension of refractory period by delaying the repolarization itself. Quinidine and disopyramide caused minor delays of repolarization, but both were primarily class 1 agents, and in addition had undesirable anticholinergic activity. Amiodarone, already in use for many years as an antianginal drug, prolonged action potential duration (APD) and was shown to have an anti-arrhythmic action in rabbits, dogs and man. Although prolongation of APD lengthens QT, a long QT may be caused by phenomena other than prolonged APD, such as heterogeneity of sympathetic drive. Association of long QT with arrhythmia does not, therefore, invalidate the principle that homogeneously prolonged APD should be anti-arrhythmic. In practice, amiodarone, bretylium, sotalol, thyroidectomy, and long-term beta-blockade prolong APD, and are associated with low incidence of arrhythmia. Many mechanisms controlling cardiac repolarization have been proposed, but how repolarization is delayed by individual agents is not fully elucidated.

  13. Bayesian outbreak detection in the presence of reporting delays.

    Science.gov (United States)

    Salmon, Maëlle; Schumacher, Dirk; Stark, Klaus; Höhle, Michael

    2015-11-01

    One use of infectious disease surveillance systems is the statistical aberration detection performed on time series of counts resulting from the aggregation of individual case reports. However, inherent reporting delays in such surveillance systems make the considered time series incomplete, which can be an impediment to the timely detection and thus to the containment of emerging outbreaks. In this work, we synthesize the outbreak detection algorithms of Noufaily et al. (2013) and Manitz and Höhle (2013) while additionally addressing right truncation caused by reporting delays. We do so by considering the resulting time series as an incomplete two-way contingency table which we model using negative binomial regression. Our approach is defined in a Bayesian setting allowing a direct inclusion of all sources of uncertainty in the derivation of whether an observed case count is to be considered an aberration. The proposed algorithm is evaluated both on simulated data and on the time series of Salmonella Newport cases in Germany in 2011. Altogether, our method aims at allowing timely aberration detection in the presence of reporting delays and hence underlines the need for statistical modeling to address complications of reporting systems. An implementation of the proposed method is made available in the R package surveillance as the function "bodaDelay". PMID:26250543

  14. Additive and polynomial representations

    CERN Document Server

    Krantz, David H; Suppes, Patrick

    1971-01-01

    Additive and Polynomial Representations deals with major representation theorems in which the qualitative structure is reflected as some polynomial function of one or more numerical functions defined on the basic entities. Examples are additive expressions of a single measure (such as the probability of disjoint events being the sum of their probabilities), and additive expressions of two measures (such as the logarithm of momentum being the sum of log mass and log velocity terms). The book describes the three basic procedures of fundamental measurement as the mathematical pivot, as the utiliz

  15. A Cold Flare With Delayed Heating

    CERN Document Server

    Fleishman, Gregory D; Meshalkina, Natalia; Lysenko, Alexandra L; Kashapova, Larisa K; Altyntsev, Alexander T

    2016-01-01

    Recently, a number of peculiar flares have been reported, which demonstrate significant non-thermal particle signatures with a low, if any, thermal emission, that implies close association of the observed emission with the primary energy release/electron acceleration region. This paper presents a flare that appears a "cold" one at the impulsive phase, while displaying a delayed heating later on. Using HXR data from \\kw, microwave observations by SSRT, RSTN, NoRH and NoRP, context observations, and 3D modeling, we study the energy release, particle acceleration and transport, and the relationships between the nonthermal and thermal signatures. The flaring process is found to involve interaction between a small and a big loop and the accelerated particles divided in roughly equal numbers between them. Precipitation of the electrons from the small loop produced only weak thermal response because the loop volume was small, while the electrons trapped in the big loop lost most of their energy in the coronal part o...

  16. Delay-dependent state feedback robust stabilization for uncertain singular time-delay systems

    Institute of Scientific and Technical Information of China (English)

    Gao Huanli; Xu Bugong

    2008-01-01

    The problem of robust stabilization for uncertain singular time-delay systems is studied.First,a new delay-dependent asymptotic stability criteria for normal singular time-delay systems is given,which is less conservative.Using this result,the problem of state feedback robust stabilization for uncertain singular time-delay systems is discussed.Finally,two examples are given to illustrate the effectiveness of the results.

  17. Food Additives and Hyperkinesis

    Science.gov (United States)

    Wender, Ester H.

    1977-01-01

    The hypothesis that food additives are causally associated with hyperkinesis and learning disabilities in children is reviewed, and available data are summarized. Available from: American Medical Association 535 North Dearborn Street Chicago, Illinois 60610. (JG)

  18. Groups – Additive Notation

    Directory of Open Access Journals (Sweden)

    Coghetto Roland

    2015-06-01

    Full Text Available We translate the articles covering group theory already available in the Mizar Mathematical Library from multiplicative into additive notation. We adapt the works of Wojciech A. Trybulec [41, 42, 43] and Artur Korniłowicz [25].

  19. A stochastically forced time delay solar dynamo model: Self-consistent recovery from a maunder-like grand minimum necessitates a mean-field alpha effect

    International Nuclear Information System (INIS)

    Fluctuations in the Sun's magnetic activity, including episodes of grand minima such as the Maunder minimum have important consequences for space and planetary environments. However, the underlying dynamics of such extreme fluctuations remain ill-understood. Here, we use a novel mathematical model based on stochastically forced, non-linear delay differential equations to study solar cycle fluctuations in which time delays capture the physics of magnetic flux transport between spatially segregated dynamo source regions in the solar interior. Using this model, we explicitly demonstrate that the Babcock-Leighton poloidal field source based on dispersal of tilted bipolar sunspot flux, alone, cannot recover the sunspot cycle from a grand minimum. We find that an additional poloidal field source effective on weak fields—e.g., the mean-field α effect driven by helical turbulence—is necessary for self-consistent recovery of the sunspot cycle from grand minima episodes.

  20. A Stochastically Forced Time Delay Solar Dynamo Model: Self-Consistent Recovery from a Maunder-like Grand Minimum Necessitates a Mean-Field Alpha Effect

    CERN Document Server

    Hazra, Soumitra; Nandy, Dibyendu

    2013-01-01

    Fluctuations in the Sun's magnetic activity, including episodes of grand minima such as the Maunder minimum have important consequences for space and planetary environments. However, the underlying dynamics of such extreme fluctuations remain ill-understood. Here we use a novel mathematical model based on stochastically forced, non-linear delay differential equations to study solar cycle fluctuations, in which, time delays capture the physics of magnetic flux transport between spatially segregated dynamo source regions in the solar interior. Using this model we explicitly demonstrate that the Babcock-Leighton poloidal field source based on dispersal of tilted bipolar sunspot flux, alone, can not recover the sunspot cycle from a grand minimum. We find that an additional poloidal field source effective on weak fields--the mean-field alpha-effect driven by helical turbulence--is necessary for self-consistent recovery of the sunspot cycle from grand minima episodes.

  1. A novel approach to synchronization of nonlinearly coupled network systems with delays

    Science.gov (United States)

    Tseng, Jui-Pin

    2016-06-01

    In this investigation, a novel approach to establishing the global synchronization of coupled network systems is presented. Under this approach, individual subsystems can be non-autonomous, and the coupling configuration is rather general. The coupling terms can be non-diffusive, nonlinear, time-dependent, asymmetric, and with time delays. With an iteration scheme, the problem of synchronization is transformed into solving a corresponding linear system of algebraic equations. Subsequently, delay-dependent and delay-independent criteria for global synchronization can be established. We implement the present approach to analyze synchronization of the FitzHugh-Nagumo systems under delayed and nonlinear sigmoidal coupling. Two examples are presented to demonstrate new dynamical scenarios, where oscillatory behavior and multistability emerge or are suppressed as the coupled neurons synchronize under the synchronization criterion. In addition, asynchrony induced by the coupling strength or coupling delay occurs while the synchronization criterion is violated.

  2. Noise transmission and delay-induced stochasticoscillations in biochemical network motifs

    Institute of Scientific and Technical Information of China (English)

    Liu Sheng-Jun; Wang Qi; Liu Bo; Yan Shi-Wei; Fumihiko Sakata

    2011-01-01

    With the aid of stochastic delayed-feedback differential equations,we derive an analytic expression for the power spectra of reacting molecules included in a generic biological network motif that is incorporated with a feedback mechanism and time delays in gene regulation.We systematically analyse the effects of time delays,the feedback mechanism,and biological stochasticity on the power spectra.It has been clarified that the time delays together with the feedback mechanism can induce stochastic oscillations at the molecular level and invalidate the noise addition rule for a modular description of the noise propagator.Delay-induced stochastic resonance can be expected,which is related to the stability loss of the reaction systems and Hopf bifurcation occurring for solutions of the corresponding deterministic reaction equations.Through the analysis of the power spectrum,a new approach is proposed to estimate the oscillation period.

  3. Two vicious circles contributing to a diagnostic delay for tuberculosis patients in Arkhangelsk

    Directory of Open Access Journals (Sweden)

    Vladimir N. Kuznetsov

    2014-08-01

    Full Text Available Setting: Delay in tuberculosis (TB diagnosis increases the infectious pool in the community and the risk of development of resistance of mycobacteria, which results in an increased number of deaths. Objective: To describe patients’ and doctors’ perceptions of diagnostic delay in TB patients in the Arkhangelsk region and to develop a substantive model to better understand the mechanisms of how these delays are linked to each other. Design: A grounded theory approach was used to study the phenomenon of diagnostic delay. Patients with TB diagnostic delay and doctors–phthisiatricians were interviewed. Results: A model named ‘sickness trajectory in health-seeking behaviour among tuberculosis patients’ was developed and included two core categories describing two vicious circles of diagnostic delay in patients with TB: ‘limited awareness of the importance to contact the health system’ and ‘limited resources of the health system’ and the categories: ‘factors influencing health-seeking behaviour’ and ‘factors influencing the health system effectiveness’. Men were more likely to report patient delay, while women were more likely to report health system delay. Conclusions: To involve people in early medical examinations, it is necessary to increase alertness on TB among patients and to improve health systems in the districts.

  4. Additively Manufactured Propulsion System

    OpenAIRE

    Dushku, Matthew; Mueller, Paul

    2012-01-01

    New high-performance, carbon-fiber reinforced polymer material allows additive manufacturing to produce pressure vessels capable of high pressures (thousands of pounds per square inch). This advancement in turn allows integral hybrid propulsion which is revolutionary for both CubeSats and additively-manufactured spacecraft. Hybrid propulsion offers simplicity as compared to bipropellant liquid propulsion, significantly better safety compared to solid or monopropellant hydrazine propulsion, an...

  5. The pathophysiology of delayed ejaculation

    Science.gov (United States)

    2016-01-01

    Delayed ejaculation (DE) is probably least studied, and least understood of male sexual dysfunctions, with an estimated prevalence of 1–4% of the male population. Pathophysiology of DE is multifactorial and including psychosexual-behavioral and cultural factors, disruption of ejaculatory apparatus, central and peripheral neurotransmitters, hormonal or neurochemical ejaculatory control and psychosocial factors. Although knowledge of the physiology of the DE has increased in the last two decade, our understanding of the different pathophysiological process of the causes of DE remains limited. To provide a systematic update on the pathophysiology of DE. A systematic review of Medline and PubMed for relevant publications on ejaculatory dysfunction (EjD), DE, retarded ejaculation, inhibited ejaculation, and climax was performed. The search was limited to the articles published between the January 1960 and December 2015 in English. Of 178 articles, 105 were selected for this review. Only those publications relevant to the pathophysiology, epidemiology and prevalence of DE were included. The pathophysiology of DE involves cerebral sensory areas, motor centers, and several spinal nuclei that are tightly interconnected. The biogenic, psychogenic and other factors strongly affect the pathophysiology of DE. Despite the many publications on this disorder, there still is a paucity of publications dedicated to the subject.

  6. Development of an acoustic steam generator leak detection system using delay-and-sum beamformer

    International Nuclear Information System (INIS)

    A new acoustic steam generator leak detection system using delay-and-sum beamformer is proposed. The major advantage of the delay-and-sum beamformer is it could provide information of acoustic source direction. An acoustic source of a sodium-water reaction is supposed to be localized while the background noise of the steam generator operation is uniformly distributed in the steam generator tube region. Therefore the delay-and-sum beamformer could distinguish the acoustic source of the sodium-water reaction from steam generator background noise. In this paper, results from numerical analyses are provided to show fundamental feasibility of the new method. (author)

  7. Stability and bifurcation analysis of a generalized scalar delay differential equation.

    Science.gov (United States)

    Bhalekar, Sachin

    2016-08-01

    This paper deals with the stability and bifurcation analysis of a general form of equation D(α)x(t)=g(x(t),x(t-τ)) involving the derivative of order α ∈ (0, 1] and a constant delay τ ≥ 0. The stability of equilibrium points is presented in terms of the stability regions and critical surfaces. We provide a necessary condition to exist chaos in the system also. A wide range of delay differential equations involving a constant delay can be analyzed using the results proposed in this paper. The illustrative examples are provided to explain the theory. PMID:27586623

  8. Synchronization of unidirectional time delay chaotic networks and the greatest common divisor

    CERN Document Server

    Kanter, I; Englert, A; Geissler, F; Kinzel, W; 10.1209/0295-5075/93/60003

    2011-01-01

    We present the interplay between synchronization of unidirectional coupled chaotic nodes with heterogeneous delays and the greatest common divisor (GCD) of loops composing the oriented graph. In the weak chaos region and for GCD=1 the network is in chaotic zero-lag synchronization, whereas for GCD=m>1 synchronization of m-sublattices emerges. Complete synchronization can be achieved when all chaotic nodes are influenced by an identical set of delays and in particular for the limiting case of homogeneous delays. Results are supported by simulations of chaotic systems, self-consistent and mixing arguments, as well as analytical solutions of Bernoulli maps.

  9. Synchronization of unidirectional time delay chaotic networks and the greatest common divisor

    Science.gov (United States)

    Kanter, I.; Zigzag, M.; Englert, A.; Geissler, F.; Kinzel, W.

    2011-03-01

    We present the interplay between synchronization of unidirectional coupled chaotic nodes with heterogeneous delays and the greatest common divisor (GCD) of loops composing the oriented graph. In the weak-chaos region and for GCD=1 the network is in chaotic zero-lag synchronization, whereas for GCD=m>1 synchronization of m-sublattices emerges. Complete synchronization can be achieved when all chaotic nodes are influenced by an identical set of delays and in particular for the limiting case of homogeneous delays. Results are supported by simulations of chaotic systems, self-consistent and mixing arguments, as well as analytical solutions of Bernoulli maps.

  10. Stability and bifurcation analysis of a generalized scalar delay differential equation

    Science.gov (United States)

    Bhalekar, Sachin

    2016-08-01

    This paper deals with the stability and bifurcation analysis of a general form of equation D α x ( t ) = g ( x ( t ) , x ( t - τ ) ) involving the derivative of order α ∈ (0, 1] and a constant delay τ ≥ 0. The stability of equilibrium points is presented in terms of the stability regions and critical surfaces. We provide a necessary condition to exist chaos in the system also. A wide range of delay differential equations involving a constant delay can be analyzed using the results proposed in this paper. The illustrative examples are provided to explain the theory.

  11. Delays in Referral of Soft Tissue Sarcomas

    Directory of Open Access Journals (Sweden)

    G. D. Johnson

    2008-01-01

    Full Text Available Introduction and aims. It is well established that soft tissue sarcomas (STSs are more effectively treated in a specialist centre. However, delays in time taken for a patient to be referred to a specialist centre may lead to a poorer prognosis. This study aims to identify the length of these delays and where they occur. Patients and methods. Patients with a proven STS were included. They were recruited from both outpatient clinics and from the surgical ward of the Royal Orthopaedic Hospital (Birmingham, UK. A structured interview was used to take a detailed history of the patients' treatment pathway, before arriving at the specialist centre. Dates given were validated using the case notes. Results. The median time for the patient to present to a specialist centre from the onset of symptoms was 40.4 weeks. The median delay until presentation to a medical professional (patient delay was 1.3 weeks. Median delay in referral to a specialist centre (service delay was 25.0 weeks. Discussion. Medical professionals rather than patients contribute the greatest source of delay in patients reaching a specialist centre for treatment of STS. Adherence to previously published guidelines could decrease this delay for diagnosis of possible sarcoma. Steps should be taken to refer patients directly to a diagnostic centre if they have symptoms or signs suggestive of STS.

  12. Test Anxiety and Academic Delay of Gratification

    Science.gov (United States)

    Bembenutty, Hefer

    2009-01-01

    The present study examined the relationship between college students' willingness to delay gratification, motivation, self-regulation of learning, and their level of test anxiety (N = 364). Academic delay of gratification refers to students' postponement of immediately available opportunities to satisfy impulses in favor of pursuing academic…

  13. Delay synchronization of temporal Boolean networks

    Science.gov (United States)

    Wei, Qiang; Xie, Cheng-jun; Liang, Yi; Niu, Yu-jun; Lin, Da

    2016-01-01

    This paper investigates the delay synchronization between two temporal Boolean networks base on semi-tensor product method, which improve complete synchronization. Necessary and sufficient conditions for delay synchronization are drawn base on algebraic expression of temporal Boolean networks. A example is presented to show the effectiveness of theoretical analysis.

  14. Congenital rubella syndrome and delayed manifestations

    DEFF Research Database (Denmark)

    Dammeyer, Jesper Herup

    2010-01-01

    Objective: Several hypotheses of different medical and psychological delayed manifestations among people who have congenital rubella syndrome (CRS) have been discussed. This study tests some of these hypotheses of delayed manifestations. Methods: Gathering information about 35 individuals who have...

  15. Stabilization of a Nonlinear Delay System

    Directory of Open Access Journals (Sweden)

    Walid Arouri

    2012-01-01

    Full Text Available Problem statement: The analysis and control of delayed systems are becoming more and more research topics in progress. This is mainly due to the fact that the delay is frequently encountered in technological systems. This can affect their significantly operations. Most control command laws are based on current digital computers and delays are intrinsic to the process or in the control loop caused by the transmission time control sequences, or computing time. The delay may affect one or more states of the considered system. It may also affect the establishment of the command. Several studies have investigated the stability of delay systems under the assumption that the delay is a variable phenomenon; such variation is considered to be bounded or limited to facilitate analysis of the system. In this study we propose a modelling of delayed system by using the multimodels and switched system theory. The analysis of stability is based on the use of second Lyapunov method. The issued stability conditions are expressed as Bilinear Matrix Inequalities impossible to resolve. That’s why we propose the same original relaxations to come over this difficulty, an example of induction machine is given to illustrate over approach. Approach: We propose to use the control theory developed for switched systems to synthesis a control laws for the stabilisation of delays system. Results: We stabilize the induction machine around many operating points despite the non linearities. Conclusion: The developed method is less conservative and less pessimistic than the used classical methods.

  16. Analyzing delay causes in Egyptian construction projects

    Directory of Open Access Journals (Sweden)

    Mohamed M. Marzouk

    2014-01-01

    Full Text Available Construction delays are common problems in civil engineering projects in Egypt. These problems occur frequently during project life-time leading to disputes and litigation. Therefore, it is essential to study and analyze causes of construction delays. This research presents a list of construction delay causes retrieved from literature. The feedback of construction experts was obtained through interviews. Subsequently, a questionnaire survey was prepared. The questionnaire survey was distributed to thirty-three construction experts who represent owners, consultants, and contractor’s organizations. Frequency Index, Severity Index, and Importance Index are calculated and according to the highest values of them the top ten delay causes of construction projects in Egypt are determined. A case study is analyzed and compared to the most important delay causes in the research. Statistical analysis is carried out using analysis of variance ANOVA method to test delay causes, obtained from the survey. The test results reveal good correlation between groups while there is significant difference between them for some delay causes and finally roadmap for prioritizing delay causes groups is presented.

  17. Delaying Developmental Mathematics: The Characteristics and Costs

    Science.gov (United States)

    Johnson, Marianne; Kuennen, Eric

    2004-01-01

    This paper investigates which students delay taking a required developmental mathematics course and the impact of delay on student performance in introductory microeconomics. Analysis of a sample of 1462 students at a large Midwestern university revealed that, although developmental-level mathematics students did not reach the same level of…

  18. Delays in the management of retroperitoneal sarcomas

    DEFF Research Database (Denmark)

    Seinen, Jojanneke; Almquist, Martin; Styring, Emelie;

    2010-01-01

    Retroperitoneal sarcomas are rare and treatment should optimally be centralized. Despite successful centralization with 90% of the patients referred prior to surgery, delays occur, which led us to assess lead times in a population-based series. Method. Patients diagnosed with retroperitoneal sarc...... indicate that development of coordinated diagnostic packages could shorten delays at the sarcoma centre....

  19. Programmable delay circuit for sparker signal analysis

    Digital Repository Service at National Institute of Oceanography (India)

    Pathak, D.

    on it to classify the seafloor sediment properties. A specific purpose oriented programmable delay circuit was developed to generate the necessary delay so that the A/D conversion could start just before the arrival of the echo from the water bottom interface...

  20. Diagnostic Delay in Women with Endometriosis

    Institute of Scientific and Technical Information of China (English)

    Xiao-man Ding; Jing-he Lang

    2005-01-01

    @@ Women affected by endometriosis claim that delayed diagnosis of endometriosis is a great problem. Studies have shown a delay from 3 to 11 years between the onset of pain symptom and the final diagnosis of endometriosis. But the diagnostic time of Chinese patients has not been reported.

  1. On Delay and Security in Network Coding

    Science.gov (United States)

    Dikaliotis, Theodoros K.

    2013-01-01

    In this thesis, delay and security issues in network coding are considered. First, we study the delay incurred in the transmission of a fixed number of packets through acyclic networks comprised of erasure links. The two transmission schemes studied are routing with hop-by-hop retransmissions, where every node in the network simply stores and…

  2. Algebraic entropy for differential-delay equations

    OpenAIRE

    Viallet, Claude M.

    2014-01-01

    We extend the definition of algebraic entropy to a class of differential-delay equations. The vanishing of the entropy, as a structural property of an equation, signals its integrability. We suggest a simple way to produce differential-delay equations with vanishing entropy from known integrable differential-difference equations.

  3. Discounting of Delayed Rewards Is Not Hyperbolic

    Science.gov (United States)

    Luhmann, Christian C.

    2013-01-01

    Delay discounting refers to decision-makers' tendency to value immediately available goods more than identical goods available only after some delay. In violation of standard economic theory, decision-makers frequently exhibit dynamic inconsistency; their preferences change simply due to the passage of time. The standard explanation for this…

  4. Corrections and additions to a list of parasites for livestock and poultry in Guangxi Zhuang Autonomous Region%《广西壮族自治区畜禽寄生虫名录》补遗与修订(Ⅱ)

    Institute of Scientific and Technical Information of China (English)

    张毅强; 黄维义

    2001-01-01

    本文是《广西壮族自治区畜禽寄生虫名录》的补遗与修订,收载了广西畜禽体内外寄生虫共计518种,隶属于7门,10纲,25目。它们包括:鞭毛虫2科,2属,2种;类锥体虫2科,4 属,46种;无类锥体虫2科,2属,4种;纤毛虫1科,1属,1种;吸虫16科,38属,95种;绦虫6科,24属,42种;线虫30科,65属,136种,棘头虫3科,3属,5种;蜱螨7科,13属,25 种;昆虫19科,38属,162种。%This paper is corrections and additions to “A list of parasites for livestock and po ultry in Guangxi Zhuang Autonomous Region”.Up to the present,a grand total of 5 18 species of parasites have been recorded.They belong to 25 orders,10 classes,7 phyla,which include:2 species,2 genera,2 families of mastigote;46 species,4 gen era,2 families of conoide;4 species,2 genera,2 families of aconoide;1 species,1 genus,1 family of cliliate;95 species,38 genera,16 families of tremat ode;42 species,24 genera,6 families of cestode;136 species,64 genera,30 familiea of nematode;5 species,3 genera,3 families of acanthocephalan;25 species,13 gene ra,7 families of arachnid;162 species,38 genera,19 families of insect.

  5. Effects of Time Delay on Stability of an Unstable State in a Bistable System with Correlated Noises

    Institute of Scientific and Technical Information of China (English)

    LI Chun; MEI Dong-Cheng

    2011-01-01

    @@ Effects of time delay on stability of an unstable state in a time-delayed bistable system are investigated.The analytic expression of the transition rate W(xu,τ)from unstable state xu to stable state x+ is derived.The numerical calculation results of W(xu,τ)indicate that W(xu,τ)decreases with the increasing multiplicative noise intensity, the additive noise intensi by and the strength of correlations between the multiplicative and the additive noise increase, but W(xu,τ)increases with increasing delay time.Namely, the multiplicative noise, the additive noise and the correlations between the multiplicative and the additive noises enhance the stability of the unstable state in the time-delayed bistable system but the stability is weakened by time delay.%Effects of time delay on stability of an unstable state in a time-delayed bistable system are investigated. The analytic expression of the transition rate W(xu, T) from unstable state xu to stable state x+ is derived. The numerical calculation results of W(xu, T) indicate that W(xu, T) decreases with the increasing multiplicative noise intensity, the additive noise intensity and the strength of correlations between the multiplicative and the additive noise increase, but W(xu, T) increases with increasing delay time. Namely, the multiplicative noise, the additive noise and the correlations between the multiplicative and the additive noises enhance the stability of the unstable state in the time-delayed bistable system but the stability is weakened by time delay.

  6. Time-dependent delayed signatures from energetic photon interrogations

    International Nuclear Information System (INIS)

    Pulsed photonuclear interrogation environments generated by 8-24 MeV electron linac are rich with time-dependent, material-specific, radiation signatures. Nitrogen-based explosives and nuclear materials can be detected by exploiting these signatures in different delayed-time regions. Numerical and experimental results presented in this paper show the unique time and energy dependence of these signatures. It is shown that appropriate delayed-time windows are essential to acquire material-specific signatures in pulsed photonuclear assessment environments. These developments demonstrate that pulsed, high-energy, photon-inspection environments can be exploited for time-dependent, material-specific signatures through the proper operation of specialized detectors and detection methods

  7. Time-Dependent Delayed Signatures from Energetic Photon Interrogations

    International Nuclear Information System (INIS)

    Pulsed photonuclear interrogation environments generated by 8-24 MeV electron linac are rich with time-dependent, material-specific, radiation signatures. Nitrogen-based explosives and nuclear materials can be detected by exploiting these signatures in different delayed-time regions. Numerical and experimental results presented in this paper show the unique time and energy dependence of these signatures. It is shown that appropriate delayed-time windows are essential to acquire material-specific signatures in the pulsed photonuclear assessment (PPA) environments. These developments demonstrate that pulsed, high-energy, photon- inspection environments can be exploited for time-dependent, material-specific signatures through the proper operation of specialized detectors and detection methods

  8. Real-time estimation of ionospheric delay using GPS measurements

    Science.gov (United States)

    Lin, Lao-Sheng

    1997-12-01

    When radio waves such as the GPS signals propagate through the ionosphere, they experience an extra time delay. The ionospheric delay can be eliminated (to the first order) through a linear combination of L1 and L2 observations from dual-frequency GPS receivers. Taking advantage of this dispersive principle, one or more dual- frequency GPS receivers can be used to determine a model of the ionospheric delay across a region of interest and, if implemented in real-time, can support single-frequency GPS positioning and navigation applications. The research objectives of this thesis were: (1) to develop algorithms to obtain accurate absolute Total Electron Content (TEC) estimates from dual-frequency GPS observables, and (2) to develop an algorithm to improve the accuracy of real-time ionosphere modelling. In order to fulfil these objectives, four algorithms have been proposed in this thesis. A 'multi-day multipath template technique' is proposed to mitigate the pseudo-range multipath effects at static GPS reference stations. This technique is based on the assumption that the multipath disturbance at a static station will be constant if the physical environment remains unchanged from day to day. The multipath template, either single-day or multi-day, can be generated from the previous days' GPS data. A 'real-time failure detection and repair algorithm' is proposed to detect and repair the GPS carrier phase 'failures', such as the occurrence of cycle slips. The proposed algorithm uses two procedures: (1) application of a statistical test on the state difference estimated from robust and conventional Kalman filters in order to detect and identify the carrier phase failure, and (2) application of a Kalman filter algorithm to repair the 'identified carrier phase failure'. A 'L1/L2 differential delay estimation algorithm' is proposed to estimate GPS satellite transmitter and receiver L1/L2 differential delays. This algorithm, based on the single-site modelling technique, is

  9. Comments on Regional Geography.

    Science.gov (United States)

    Taaffe, Edward J.

    1985-01-01

    Reasons why regional geography should play a vital role in the development of U.S. geography are discussed. In addition, problems facing regional geographers are examined. A revival of regional geography can be significantly strengthened if there is more effective communication between regional and scientific geographers. (RM)

  10. Ice Formation Delay on Penguin Feathers

    Science.gov (United States)

    Alizadehbirjandi, Elaheh; Tavakoli-Dastjerdi, Faryar; St. Leger, Judy; Davis, Stephen H.; Rothstein, Jonathan P.; Kavehpour, H. Pirouz

    2015-11-01

    Antarctic penguins reside in a harsh environment where air temperature may reach -40 °C with wind speed of 40 m/s and water temperature remains around -2.2 °C. Penguins are constantly in and out of the water and splashed by waves, yet even in sub-freezing conditions, the formation of macroscopic ice is not observed on their feathers. Bird feathers are naturally hydrophobic; however, penguins have an additional hydrophobic coating on their feathers to reinforce their non-wetting properties. This coating consists of preen oil which is applied to the feathers from the gland near the base of the tail. The combination of the feather's hydrophobicity and surface texture is known to increase the contact angle of water drops on penguin feathers to over 140 ° and classify them as superhydrophobic. We here develop an in-depth analysis of ice formation mechanism on superhydrophobic surfaces through careful experimentations and development of a theory to address how ice formation is delayed on these surfaces. Furthermore, we investigate the anti-icing properties of warm and cold weather penguins with and without preen oil to further design a surface minimizing the frost formation which is of practical interest especially in aircraft industry.

  11. Delayed gait recovery in a stroke patient.

    Science.gov (United States)

    Seo, Jeong Pyo; Lee, Mi Young; Kwon, Yong Hyun; Jang, Sung Ho

    2013-06-01

    We report on a stroke patient who showed delayed gait recovery between 8 and 11 months after the onset of intracerebral hemorrhage. This 32-year-old female patient underwent craniotomy and drainage for right intracerebral hemorrhage due to rupture of an arteriovenous malformation. Brain MR images revealed a large leukomalactic lesion in the right fronto-parietal cortex. Diffusion tensor tractography at 8 months after onset revealed that the right corticospinal tract was severely injured. At this time, the patient could not stand or walk despite undergoing rehabilitation from 2 months after onset. It was believed that severe spasticity of the left leg and right ankle was largely responsible, and thus, antispastic drugs, antispastic procedures (alcohol neurolysis of the motor branch of the tibial nerve and an intramuscular alcohol wash of both tibialis posterior muscles) and physical therapy were tried to control the spasticity. These measures relieved the severe spasticity, with the result that the patient was able to stand at 3 months. In addition, the improvements in sensorimotor function, visuospatial function, and cognition also seemed to contribute to gait recovery. As a result, she gained the ability to walk independently on even floor with a left ankle foot orthosis at 11 months after onset. This case illustrates that clinicians should attempt to find the cause of gait inability and to initiate intensive rehabilitation in stroke patients who cannot walk at 3-6 months after onset. PMID:25206447

  12. Delayed gait recovery in a stroke patient

    Institute of Scientific and Technical Information of China (English)

    Jeong Pyo Seo; Mi Young Lee; Yong Hyun Kwon; Sung Ho Jang

    2013-01-01

    We report on a stroke patient who showed delayed gait recovery between 8 and 11 months after the onset of intracerebral hemorrhage. This 32-year-old female patient underwent craniotomy and drainage for right intracerebral hemorrhage due to rupture of an arteriovenous malformation. Brain MR images revealed a large leukomalactic lesion in the right fronto-parietal cortex. Diffusion tensor tractography at 8 months after onset revealed that the right corticospinal tract was severely injured. At this time, the patient could not stand or walk despite undergoing rehabilitation from 2 months after onset. It was believed that severe spasticity of the left leg and right ankle was largely responsible, and thus, antispastic drugs, antispastic procedures (alcohol neurolysis of the motor branch of the tibial nerve and an intramuscular alcohol wash of both tibialis posterior muscles) and physical therapy were tried to control the spasticity. These measures relieved the severe spasticity, with the result that the patient was able to stand at 3 months. In addition, the improvements in sensorimotor function, visuospatial function, and cognition also seemed to contribute to gait recovery. As a result, she gained the ability to walk independently on even floor with a left ankle foot orthosis at 11 months after onset. This case illustrates that clinicians should attempt to find the months after onset.

  13. Additive Manufacturing Infrared Inspection

    Science.gov (United States)

    Gaddy, Darrell

    2014-01-01

    Additive manufacturing is a rapid prototyping technology that allows parts to be built in a series of thin layers from plastic, ceramics, and metallics. Metallic additive manufacturing is an emerging form of rapid prototyping that allows complex structures to be built using various metallic powders. Significant time and cost savings have also been observed using the metallic additive manufacturing compared with traditional techniques. Development of the metallic additive manufacturing technology has advanced significantly over the last decade, although many of the techniques to inspect parts made from these processes have not advanced significantly or have limitations. Several external geometry inspection techniques exist such as Coordinate Measurement Machines (CMM), Laser Scanners, Structured Light Scanning Systems, or even traditional calipers and gages. All of the aforementioned techniques are limited to external geometry and contours or must use a contact probe to inspect limited internal dimensions. This presentation will document the development of a process for real-time dimensional inspection technique and digital quality record of the additive manufacturing process using Infrared camera imaging and processing techniques.

  14. Delay-Limited Capacity in the Low Power Regime

    KAUST Repository

    Rezki, Zouheir

    2016-02-11

    Outage performance of the M-block fading with additive white Gaussian noise (BF-AWGN) is investigated in the low-power regime. We consider delay-constrained constant-rate communications with perfect channel state information (CSI) at both the transmitter and the receiver (CSI-TR), under a shortterm power constraint (STPC) and a long-term power constraint (LTPC). Subject to STPC, we show that selection diversity that allocates all the power to the strongest block is asymptotically optimal. Then, we provide a simple characterization of the outage probability in the regime of interest. We quantify the reward due to CSI-TR over the constant-rate constant-power scheme and show that this reward increases with the delay constraint. For instance, for Rayleigh fading, we find that a power gain up to 4.3 dB is achievable. Subject to LTPC, we show that the above guidelines still holds and that the outage performance improves due to the flexibility of the LTPC over the STPC. More interestingly, we prove that LTPC allows zero-outage communication even at low SNR and characterize the delaylimited capacity at low SNR in a simple form. More precisely, we establish that the delay-limited capacity scales linearly with the power constraint, for a given M < 1. Our framework highlights the benefit of fading at low SNR as the delay-limited capacity may outperform the AWGN capacity. For instance, for Rayleigh fading and with M = 3, the delay-limited capacity is 16% higher than the capacity of an AWGN channel.

  15. Stochastic modeling of biochemical systems with multistep reactions using state-dependent time delay.

    Science.gov (United States)

    Wu, Qianqian; Tian, Tianhai

    2016-01-01

    To deal with the growing scale of molecular systems, sophisticated modelling techniques have been designed in recent years to reduce the complexity of mathematical models. Among them, a widely used approach is delayed reaction for simplifying multistep reactions. However, recent research results suggest that a delayed reaction with constant time delay is unable to describe multistep reactions accurately. To address this issue, we propose a novel approach using state-dependent time delay to approximate multistep reactions. We first use stochastic simulations to calculate time delay arising from multistep reactions exactly. Then we design algorithms to calculate time delay based on system dynamics precisely. To demonstrate the power of proposed method, two processes of mRNA degradation are used to investigate the function of time delay in determining system dynamics. In addition, a multistep pathway of metabolic synthesis is used to explore the potential of the proposed method to simplify multistep reactions with nonlinear reaction rates. Simulation results suggest that the state-dependent time delay is a promising and accurate approach to reduce model complexity and decrease the number of unknown parameters in the models. PMID:27553753

  16. Effects of intrinsic stochasticity on delayed reaction-diffusion patterning systems

    KAUST Repository

    Woolley, Thomas E.

    2012-05-22

    Cellular gene expression is a complex process involving many steps, including the transcription of DNA and translation of mRNA; hence the synthesis of proteins requires a considerable amount of time, from ten minutes to several hours. Since diffusion-driven instability has been observed to be sensitive to perturbations in kinetic delays, the application of Turing patterning mechanisms to the problem of producing spatially heterogeneous differential gene expression has been questioned. In deterministic systems a small delay in the reactions can cause a large increase in the time it takes a system to pattern. Recently, it has been observed that in undelayed systems intrinsic stochasticity can cause pattern initiation to occur earlier than in the analogous deterministic simulations. Here we are interested in adding both stochasticity and delays to Turing systems in order to assess whether stochasticity can reduce the patterning time scale in delayed Turing systems. As analytical insights to this problem are difficult to attain and often limited in their use, we focus on stochastically simulating delayed systems. We consider four different Turing systems and two different forms of delay. Our results are mixed and lead to the conclusion that, although the sensitivity to delays in the Turing mechanism is not completely removed by the addition of intrinsic noise, the effects of the delays are clearly ameliorated in certain specific cases. © 2012 American Physical Society.

  17. From additivity to synergism

    DEFF Research Database (Denmark)

    Ritz, Christian; Streibig, Jens Carl

    2014-01-01

    Interest in synergistic or antagonistic effects through mixture experiments has grown immensely over the past two decades, not the least within in pharmacology and toxicology. Several definitions of reference models exist; one commonly used reference model is concentration or dose addition, which...... assumes compounds, when administrated simultaneously, do not interfere with each other at the site of action. We focus on statistical modelling that allows evaluation of dose addition. We will describe several statistical approaches that are suitable for analysis mixture data where synergistic...... or antagonistic effects may be present. The statistical models are defined and explained and some of the approaches exemplified. Code in open-source software is provided....

  18. Alternative additives; Alternative additiver

    Energy Technology Data Exchange (ETDEWEB)

    2007-08-15

    In this project a number of industrial and agricultural waste products have been characterised and evaluated in terms of alkali-getter performance. The intended use is for biomass-fired power stations aiming at reducing corrosion or slagging related problems. The following products have been obtained, characterised and evaluated: 1) Brewery draff 2) Danish de-gassed manure 3) Paper sludge 4) Moulding sand 5) Spent bleaching earth 6) Anorthosite 7) Sand 8) Clay-sludge. Most of the above alternative additive candidates are deemed unsuitable due to insufficient chemical effect and/or expensive requirements for pre-treatment (such as drying and transportation). 3 products were selected for full-scale testing: de-gassed manure, spent bleaching earth and clay slugde. The full scale tests were undertaken at the biomass-fired power stations in Koege, Slagelse and Ensted. Spent bleaching earth (SBE) and clay sludge were the only tested additive candidates that had a proven ability to react with KCl, to thereby reduce Cl-concentrations in deposits, and reduce the deposit flux to superheater tubes. Their performance was shown to nearly as good as commercial additives. De-gassed manure, however, did not evaluate positively due to inhibiting effects of Ca in the manure. Furthermore, de-gassed manure has a high concentration of heavy metals, which imposes a financial burden with regard to proper disposal of the ash by-products. Clay-sludge is a wet clay slurring, and drying and transportation of this product entails substantial costs. Spent bleaching does not require much pre-treatment and is therefore the most promising alternative additive. On the other hand, bleaching earth contains residual plant oil which means that a range of legislation relating to waste combustion comes into play. Not least a waste combustion fee of 330 DKK/tonne. For all alternative (and commercial) additives disposal costs of the increase ash by-products represents a significant cost. This is

  19. Additives for the Axe

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    On May 1,China will begin to ban the production and use of two food additives commonly used to "bleach" flour,benzoyl peroxide and calcium peroxide.The decision was made after 10 years of wrangling between the policy makers,manufacturers,scientists and consumers.The Ministry of Health said in a statement it was applying the ban in response to consumers’ concerns about chemical substances in food,and technical improvements that had made the two additives unnecessary in flour processing.Minister of Health Chen Zhu has also said

  20. Stability criteria for T-S fuzzy systems with interval time-varying delays and nonlinear perturbations based on geometric progression delay partitioning method.

    Science.gov (United States)

    Chen, Hao; Zhong, Shouming; Li, Min; Liu, Xingwen; Adu-Gyamfi, Fehrs

    2016-07-01

    In this paper, a novel delay partitioning method is proposed by introducing the theory of geometric progression for the stability analysis of T-S fuzzy systems with interval time-varying delays and nonlinear perturbations. Based on the common ratio α, the delay interval is unequally separated into multiple subintervals. A newly modified Lyapunov-Krasovskii functional (LKF) is established which includes triple-integral terms and augmented factors with respect to the length of every related proportional subintervals. In addition, a recently developed free-matrix-based integral inequality is employed to avoid the overabundance of the enlargement when dealing with the derivative of the LKF. This innovative development can dramatically enhance the efficiency of obtaining the maximum upper bound of the time delay. Finally, much less conservative stability criteria are presented. Numerical examples are conducted to demonstrate the significant improvements of this proposed approach. PMID:27138648

  1. Survey of time preference, delay discounting models

    Directory of Open Access Journals (Sweden)

    John R. Doyle

    2013-03-01

    Full Text Available The paper surveys over twenty models of delay discounting (also known as temporal discounting, time preference, time discounting, that psychologists and economists have put forward to explain the way people actually trade off time and money. Using little more than the basic algebra of powers and logarithms, I show how the models are derived, what assumptions they are based upon, and how different models relate to each other. Rather than concentrate only on discount functions themselves, I show how discount functions may be manipulated to isolate rate parameters for each model. This approach, consistently applied, helps focus attention on the three main components in any discounting model: subjectively perceived money; subjectively perceived time; and how these elements are combined. We group models by the number of parameters that have to be estimated, which means our exposition follows a trajectory of increasing complexity to the models. However, as the story unfolds it becomes clear that most models fall into a smaller number of families. We also show how new models may be constructed by combining elements of different models. The surveyed models are: Exponential; Hyperbolic; Arithmetic; Hyperboloid (Green and Myerson, Rachlin; Loewenstein and Prelec Generalized Hyperboloid; quasi-Hyperbolic (also known as beta-delta discounting; Benhabib et al's fixed cost; Benhabib et al's Exponential / Hyperbolic / quasi-Hyperbolic; Read's discounting fractions; Roelofsma's exponential time; Scholten and Read's discounting-by-intervals (DBI; Ebert and Prelec's constant sensitivity (CS; Bleichrodt et al.'s constant absolute decreasing impatience (CADI; Bleichrodt et al.'s constant relative decreasing impatience (CRDI; Green, Myerson, and Macaux's hyperboloid over intervals models; Killeen's additive utility; size-sensitive additive utility; Yi, Landes, and Bickel's memory trace models; McClure et al.'s two exponentials; and Scholten and Read's trade

  2. Millisecond laser machining of transparent materials assisted by a nanosecond laser with different delays.

    Science.gov (United States)

    Pan, Yunxiang; Lv, Xueming; Zhang, Hongchao; Chen, Jun; Han, Bing; Shen, Zhonghua; Lu, Jian; Ni, Xiaowu

    2016-06-15

    A millisecond laser combined with a nanosecond laser was applied to machining transparent materials. The influences of delay between the two laser pulses on processing efficiencies and modified sizes were studied. In addition, a laser-supported combustion wave (LSCW) was captured during laser irradiation. An optimal delay corresponding to the highest processing efficiency was found for cone-shaped cavities. The modified size as well as the lifetime and intensity of the LSCW increased with the delay decreasing. Thermal cooperation effects of defects, overlapping effects of small modified sites, and thermal radiation from LSCW result in all the phenomena.

  3. Directed Current Induced by an Symmetrically ac Force Coexisting with a Time-Delayed Feedback

    Institute of Scientific and Technical Information of China (English)

    易述婷; 宋晖; 欧志娥; 艾保全; 熊建文

    2012-01-01

    We study the transport of overdamped Brownian particles in a symmetricaJly periodic potential in the presence of an asymmetrically ac driving force and a time-delayed feedback. It is found that for low frequencies, the average velocity can be negative by changing the driving amplitude, for high frequencies, there exists an optimized driving amplitude at which the average velocity takes its maximum value. Additionally, there is a threshold value of driving amplitude below which no directed transport can be obtained for high frequencies. For the large value of the delay time, the average velocity is independent of the delay time.

  4. Robustness Analysis of Hybrid Stochastic Neural Networks with Neutral Terms and Time-Varying Delays

    Directory of Open Access Journals (Sweden)

    Chunmei Wu

    2015-01-01

    Full Text Available We analyze the robustness of global exponential stability of hybrid stochastic neural networks subject to neutral terms and time-varying delays simultaneously. Given globally exponentially stable hybrid stochastic neural networks, we characterize the upper bounds of contraction coefficients of neutral terms and time-varying delays by using the transcendental equation. Moreover, we prove theoretically that, for any globally exponentially stable hybrid stochastic neural networks, if additive neutral terms and time-varying delays are smaller than the upper bounds arrived, then the perturbed neural networks are guaranteed to also be globally exponentially stable. Finally, a numerical simulation example is given to illustrate the presented criteria.

  5. Millisecond laser machining of transparent materials assisted by a nanosecond laser with different delays.

    Science.gov (United States)

    Pan, Yunxiang; Lv, Xueming; Zhang, Hongchao; Chen, Jun; Han, Bing; Shen, Zhonghua; Lu, Jian; Ni, Xiaowu

    2016-06-15

    A millisecond laser combined with a nanosecond laser was applied to machining transparent materials. The influences of delay between the two laser pulses on processing efficiencies and modified sizes were studied. In addition, a laser-supported combustion wave (LSCW) was captured during laser irradiation. An optimal delay corresponding to the highest processing efficiency was found for cone-shaped cavities. The modified size as well as the lifetime and intensity of the LSCW increased with the delay decreasing. Thermal cooperation effects of defects, overlapping effects of small modified sites, and thermal radiation from LSCW result in all the phenomena. PMID:27304294

  6. Delays in Building Construction Projects in Ghana

    Directory of Open Access Journals (Sweden)

    Adwoa B Agyakwah-Baah

    2010-07-01

    Full Text Available This study investigates the causes of delay of building construction projects in Ghana to determine the most important according to the key project participants; clients, consultants, and contractors. Thirty-two possible causes of delay were identified from the literature and semi-structured interviews of 15 key players in the implementation process. These delay factors were further categorised into nine major groups. The list of delay causes was subjected to a questionnaire survey for the identification of the most important causes of delay. The field survey included 130 respondents made up of 39 contractors, 37 clients and 54 consultants. The relative importance of the individual causes and the groups were calculated and ranked by their relative importance index. The overall results of the study indicate that the respondents generally agree that financial group factors ranked highest among the major factors causing delay in construction projects in Ghana. The financial group factors were delay in honouring payment certificates, difficulty in accessing credit and fluctuation in prices. Materials group factors are second followed by scheduling and controlling factors.

  7. Multipath time delay estimation of underwater acoustic sinusoidal signals

    Institute of Scientific and Technical Information of China (English)

    TONG Feng; XU Xiaomei; FANG Shiliang

    2009-01-01

    To overcome the performance limitation of multipath time-delay estimation posed by underwater acoustic sinusoidal signals, an approach incorporating the frequency-domain weighting of the highly oscillatory Nonlinear Least Squares (NLS) cost function with the evolutionary optimization was proposed to facilitate the accurate estimation of the multipath timedelay of sinusoidal signals. In the described method, the number of the effective multipath signals, which is included into the parameter model as well as the multipath time-delay and amplitude factor, can be estimated simultaneously thus avoiding the requirement of additional computation. The experimental results performed with numerical simulation and sea-trial data are provided, demonstrating the effectiveness and precision enhancement of the proposed algorithm.

  8. Construction of New Delay-Tolerant Space-Time Codes

    CERN Document Server

    Sarkiss, Mireille; Damen, Mohamed Oussama; Belfiore, Jean-Claude

    2010-01-01

    Perfect Space-Time Codes (STC) are optimal codes in their original construction for Multiple Input Multiple Output (MIMO) systems. Based on Cyclic Division Algebras (CDA), they are full-rate, full-diversity codes, have Non-Vanishing Determinants (NVD) and hence achieve Diversity-Multiplexing Tradeoff (DMT). In addition, these codes have led to optimal distributed space-time codes when applied in cooperative networks under the assumption of perfect synchronization between relays. However, they loose their diversity when delays are introduced and thus are not delay-tolerant. In this paper, using the cyclic division algebras of perfect codes, we construct new codes that maintain the same properties as perfect codes in the synchronous case. Moreover, these codes preserve their full-diversity in asynchronous transmission.

  9. Noise-enhanced phase synchronization in time-delayed systems.

    Science.gov (United States)

    Senthilkumar, D V; Shrii, M Manju; Kurths, J

    2012-02-01

    We investigate the phenomenon of noise-enhanced phase synchronization (PS) in coupled time-delay systems, which usually exhibit non-phase-coherent attractors with complex topological properties. As a delay system is essentially an infinite dimensional in nature with multiple characteristic time scales, it is interesting and crucial to understand the interplay of noise and the time scales in achieving PS. In unidirectionally coupled systems, the response system adjust all its time scales to that of the drive, whereas both subsystems adjust their rhythms to a single (main time scale of the uncoupled system) time scale in bidirectionally coupled systems. We find similar effects for both a common and an independent additive Gaussian noise.

  10. Remote optimal state estimation over communication channels with random delays

    KAUST Repository

    Mahmoud, Magdi S.

    2014-01-22

    This paper considers the optimal estimation of linear systems over unreliable communication channels with random delays. In this work, it is assumed that the system to be estimated is far away from the filter. The observations of the system are capsulized without time stamp and then transmitted to the network node at which the filter is located. The probabilities of time delays are assumed to be known. The event-driven estimation scheme is applied in this paper and the estimate of the states is updated only at each time instant when any measurement arrives. To capture the feature of communication, the system considered is augmented, and the arrived measurements are regarded as the uncertain observations of the augmented system. The corresponding optimal estimation algorithm is proposed and additionally, a numerical simulation represents the performance of this work. © 2014 The authors. Published by Oxford University Press on behalf of the Institute of Mathematics and its Applications. All rights reserved.

  11. Parenting Children with Developmental Delays: The Role of Positive Beliefs.

    Science.gov (United States)

    Paczkowski, Emilie; Baker, Bruce L

    2008-07-01

    Parents of children with developmental delays consistently report higher levels of child behavior problems and also parenting stress than parents of typically developing children. This study examined how mothers' positive beliefs influence the relation between children's behavior problems and mothers' parenting stress among families of children who are developmentally delayed (DD: n = 72) or typically developing (TD: n = 95) and assessed at ages 3, 5, and 7 years. Positive beliefs had a main effect on parenting stress at all ages, which was mediated by child behavior problems for mothers in the DD group at every age and across time. In the TD group, mediation was found at age 3 years. Additionally, support was found for a moderation effect of positive beliefs on the relation between child behavior problems and parenting stress, but only in the DD group at age 3. These findings have implications for interventions drawing on Seligman's (1991) work on learned optimism, the positive counterpart of learned helplessness. PMID:20107620

  12. Equilibrium and Disequilibrium Dynamics in Cobweb Models with Time Delays

    Science.gov (United States)

    Gori, Luca; Guerrini, Luca; Sodini, Mauro

    2015-06-01

    This paper aims to study price dynamics in two different continuous time cobweb models with delays close to [Hommes, 1994]. In both cases, the stationary equilibrium may be not representative of the long-term dynamics of the model, since it is possible to observe endogenous and persistent fluctuations (supercritical Hopf bifurcations) even if a deterministic context without external shocks is considered. In the model in which markets are in equilibrium every time, we show that the existence of time delays in the expectations formation mechanism may cause chaotic dynamics similar to those obtained in [Hommes, 1994] in a discrete time context. From a mathematical point of view, we apply the Poincaré-Lindstedt perturbation method to study the local dynamic properties of the models. In addition, several numerical experiments are used to investigate global properties of the systems.

  13. Delay-dependent robust H∞ controller design for a class of nonlinear uncertainty time-delay systems with input delay

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Based on an appropriate Lyapunov function,this paper analyzes the design of a delay-dependent robust H∞ state feedback control,with a focus on a class of non linear uncertainty linear time-delay systems with input delay using linear matrix inequalities.Under the condition that the nonlinear uncertain functions are gain bounded,a sufficient condition dependent on the delays of the state and input is presented for the existence of H∞ controller.The proposed controller not only stabilized closed-loop uncertain systems but also guaranteed a prescribed H∞ norm bound of closed-loop transfer matrix from the disturbance to controlled output.By solving a linear matrix inequation,we can obtain the robust H∞ controller.An example is given to show the effectiveness of the proposed method.

  14. Technical Progress of China's Delayed Coking Technology

    Institute of Scientific and Technical Information of China (English)

    Zhang Lixin; Li Hejie

    2005-01-01

    This article introduces the recent advances of China in the fields of process technology of delayed coking, enlarged equipment size, hydraulic decoking, automatic control and environmental protection. By the end of 2004 the total capacity of delayed coking units in China had reached 37.24Mt/a with the maximum coke drum diameter equating to 9.4 m. This article also presents the investment in delayed cokers and the current production status while pointing out the existing problems and future development trends.

  15. Delayed self-synchronization in homoclinic chaos

    Science.gov (United States)

    Arecchi, F. T.; Meucci, R.; Allaria, E.; di Garbo, A.; Tsimring, L. S.

    2002-04-01

    The chaotic spike train of a homoclinic dynamical system is self-synchronized by applying a time-delayed correction proportional to the laser output intensity. Due to the sensitive nature of the homoclinic chaos to external perturbations, stabilization of very long-periodic orbits is possible. On these orbits, the dynamics appears chaotic over a finite time, but then it repeats with a recurrence time that is slightly longer than the delay time. The effect, called delayed self-synchronization, displays analogies with neurodynamic events that occur in the buildup of long-term memories.

  16. Synchronisation of time-delay systems

    CERN Document Server

    Bünner, M J; Bünner, Martin J.; Just, Wolfram

    1998-01-01

    We present the linear-stability analysis of synchronised states in coupled time-delay systems. There exists a synchronisation threshold, for which we derive upper bounds, which does not depend on the delay time. We prove that at least for scalar time-delay systems synchronisation is achieved by transmitting a single scalar signal, even if the synchronised solution is given by a high-dimensional chaotic state with a large number of positive Lyapunov-exponents. The analytical results are compared with numerical simulations of two coupled Mackey-Glass equations.

  17. Statistical Elmore delay of RC interconnect tree

    Institute of Scientific and Technical Information of China (English)

    Dong Gang; Yang Yang; Chai Chang-Chun; Yang Yin-Tang

    2010-01-01

    As feature size keeps scaling down, process variations can dramatically reduce the accuracy in the estimation of interconnect performance. This paper proposes a statistical Elmore delay model for RC interconnect tree in the presence of process variations. The suggested method translates the process variations into parasitic parameter extraction and statistical Elmore delay evaluation. Analytical expressions of mean and standard deviation of interconnect delay can be obtained in a given fluctuation range of interconnect geometric parameters. Experimental results demonstrate that the approach matches well with Monte Carlo simulations. The errors of proposed mean and standard deviation are less than 1% and 7%, respectively. Simulations prove that our model is efficient and accurate.

  18. ON FEEDBACK CONTROL OF DELAYED CHAOTIC SYSTEM

    Institute of Scientific and Technical Information of China (English)

    李丽香; 彭海朋; 卢辉斌; 关新平

    2001-01-01

    In this paper two different types of feedback control technique are discussed: the standard feedback control and the time-delay feedback control which have been successfully used in many control systems. In order to understand to what extent the two different types of control technique are useful in delayed chaotic systems, some analytic stabilization conditions for chaos control from the two types of control technique are derived based on Lyapunov stabilization arguments. Similarly, we discuss the tracking problem by applying the time-delay feedback control. Finally, numerical examples are provided.

  19. STABILITY OF DISCRETE-TIME COHEN-GROSSBERG BAM NEURAL NETWORKS WITH DELAYS

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    In this paper, we study the existence and stability of an equilibrium of discrete-time Cohen-Grossberg BAM Neural Networks with delays. We obtain several sufficient conditions ensuring the existence and stability of an equilibrium of such systems, using discrete Halanay-type inequality and vector Lyapunov methods. In addition, we show that the proposed sufficient condition is independent of the delay parameter. An example is given to demonstrate the effectiveness of the results obtained.

  20. Ignition delay times of shock-heated tetraethoxysilane, hexamethyldisiloxane, and titanium tetraisopropoxide

    Science.gov (United States)

    Abdali, A.; Fikri, M.; Orthner, H.; Wiggers, H.; Schulz, C.

    2014-05-01

    Ignition delay times of tetraethoxysilane (TEOS), hexamethyldisiloxane (HMDSO) and titanium tetraisopropoxide (TTIP) were determined from the onset of chemiluminescence in shock-tube experiments behind reflected shock waves in dry as well as in humid gas mixtures. Additionally, the ignition delay times of TEOS and HMDSO have been investigated in humid air and as a function of water vapor concentration in the initial gas mixture.

  1. Control of unstable steady states by extended time-delayed feedback

    OpenAIRE

    Dahms, Thomas; Hoevel, Philipp; Schoell, Eckehard

    2007-01-01

    Time-delayed feedback methods can be used to control unstable periodic orbits as well as unstable steady states. We present an application of extended time delay autosynchronization introduced by Socolar et al. to an unstable focus. This system represents a generic model of an unstable steady state which can be found for instance in a Hopf bifurcation. In addition to the original controller design, we investigate effects of control loop latency and a bandpass filter on the domain of control. ...

  2. Global exponential stability of mixed discrete and distributively delayed cellular neural network

    Institute of Scientific and Technical Information of China (English)

    Yao Hong-Xing; Zhou Jia-Yan

    2011-01-01

    This paper concernes analysis for the global exponential stability of a class of recurrent neural networks with mixed discrete and distributed delays. It first proves the existence and uniqueness of the balance point, then by employing the Lyapunov-Krasovskii functional and Young inequality, it gives the sufficient condition of global exponential stability of cellular neural network with mixed discrete and distributed delays, in addition, the example is provided to illustrate the applicability of the result.

  3. Robustness Analysis of Hybrid Stochastic Neural Networks with Neutral Terms and Time-Varying Delays

    OpenAIRE

    Chunmei Wu; Junhao Hu; Yan Li

    2015-01-01

    We analyze the robustness of global exponential stability of hybrid stochastic neural networks subject to neutral terms and time-varying delays simultaneously. Given globally exponentially stable hybrid stochastic neural networks, we characterize the upper bounds of contraction coefficients of neutral terms and time-varying delays by using the transcendental equation. Moreover, we prove theoretically that, for any globally exponentially stable hybrid stochastic neural networks, if additive ne...

  4. Analysis of boundary point (break point) in Linear Delay Model for nanoscale VLSI standard cell library characterization at PVT corners

    CERN Document Server

    Agarwal, Gaurav Kumar

    2014-01-01

    In VLSI chip design flow, Static Timing Analysis (STA) is used for fast and accurate analysis of data-path delay. This process is fast because delay is picked from Look Up Tables (LUT) rather than conventional SPICE simulations. But accuracy of this method depends upon the underlying delay model with which LUT was characterized. Non Linear Delay Model (NLDM) based LUTs are quite common in industries. These LUT requires huge amount to time during characterization because of huge number of SPICE simulations done at arbitrary points. To improve this people proposed various other delay models like alpha-power and piecewise linear delay models. Bulusu et al proposed Linear Delay Model(LDM) which reduces LUT generation time to 50 percent. LDM divides delay curve w.r.t input rise time(trin) into two different region one is linear and other is non-linear. This boundary point between linear and non- linear region was called break point (trb). Linear region will be done if we simulate at only two points. This advantage...

  5. Additives in swine nutrition

    OpenAIRE

    Sinovec Zlatan J.; Jokić Živan; Šefer Dragan

    2002-01-01

    To attain better feed utilization, longer preservation, easier manipultion and higher production and better quality of food of animal orgin as the final goal, besides raw materials, feed mixes contain numerous pronutrients (additives), added to perform different effects, in a narrower sense, the term pronutrient implies heterogenous substances, which have no diverse effects and have to be efficient in the manner of use. Basically, all pronutrients have to reach the goal of keeping optimal ani...

  6. The Role of Drugs, Diet, and Food Additives in Hyperactivity.

    Science.gov (United States)

    Harshbarger, Mary E.

    A variety of causes have been suggested for hyperactivity: anoxia and other adverse birth conditions, genetic factors, delayed maturation, maternal smoking and drinking during pregnancy, interaction of temperament and environment, lead poisoning, radiation stress, allergy and food additives, and deprivation of required stimulation. Treatments…

  7. Additional protocol experience in Romania

    International Nuclear Information System (INIS)

    inconsistencies identified by the IAEA during its verification and evaluation activities. During 2001-2006 the IAEA performed in Romania 21 complementary accesses and took 21 samples. Training for the implementation of the Additional Protocol started in 2001 with a national seminar organized by the IAEA and CNCAN. In 2003 IAEA and CNCAN organized a regional seminar on the Additional Protocol implementation during 2004 - 2005 national seminars. (author)

  8. Severn barrage project. Additional regional studies 1991-1993

    International Nuclear Information System (INIS)

    These appendices contain summaries of the principle effects of barrage construction on different local authority areas and on transportation of labour. Recreation and tourism policies, current planning policy, potential development pressure, drainage, estuary management, coastal zone protection and planning, and a model simulating the behaviour of locks handling traffic with tidal constraints are discussed. Existing legislation is also considered. (UK)

  9. GBR技术用于上颌前牙唇侧骨缺损的延期种植修复的效果观察%Clinical Effect of Guided Bone Regeneration in Delayed Implant Restoration of Bone Defects in the Maxillary Anterior Region

    Institute of Scientific and Technical Information of China (English)

    沈汉

    2015-01-01

    Objective To probe into the effect of double guided bone regeneration applied in delayed implant restoration of bone defects in the maxillary anterior region. Methods The selected study subjects, twelve outpatients from January 2012 to August 2013 in Stomatological Hospital of Yangzhou restored partial bone defects after the primary GBR treatment on the conditon of the alveolar bone resorption and serious bone implant thinning due to cyst of jaw, trauma, dental caries or periodontal disease after the removal of the anterior teeth. The implants were inserted and GBR technique was applied once again 4-6 months later after the healing. Stage II surgeries of dental implantion were done 4-6 months later and dental crown restoration was completed. All the cases in the repair were taken local dental and oral panoramic X-rays at post-operation simultaneously, 3 months later, 6 months later and 12 months later respectively. Follow-up comparisons in peri implant bone level, bone density and osseointergration degree were conducted. Results Two cases of patients with GBR technology and 12 cases of implant were used in the process of planting, and the results showed that the X film was closely related to the alveolar bone. Conclusion The results showed that in all cases with 6 months to 12 months loading the peri implant bone level was stable locating above the first thread and ideal osseointergration was achieved.%目的:观察两次运用引导骨再生技术(GBR)在上颌前牙唇侧区骨质严重缺损种植修复中的应用效果。方法选取2012年1月~2013年8月我院收治的因外伤或颌骨囊肿拔牙后导致牙槽骨严重缺损患者12例作为研究对象,在首次进行GBR恢复部分骨缺损,愈合4~6个月后,再进行种植体植入术,同时再次使用GBR技术。术后4~6月进行种植二期、牙冠修复完成,所有患者均在修复完成当天、3个月、6个月、12个月行局部牙片和口腔全景片,对比种植

  10. Does Bilingualism Delay the Development of Dementia?

    Directory of Open Access Journals (Sweden)

    Amy L Atkinson

    2016-08-01

    Full Text Available It has been suggested that bilingualism (where individuals speak two languages may delay the development of dementia. However, much of the research is inconclusive. Some researchers have reported that bilingualism delays the onset and diagnosis of dementia, whilst other studies have found weak or even detrimental effects. This paper reviews a series of nine empirical studies, published up until March 2016, which investigated whether bilingualism significantly delays the onset of dementia. The article also explores whether the inconsistent findings can be attributed to differences in study designs or the definitions of bilingualism used between studies. Based on current evidence, it appears that lifelong bilingualism, where individuals frequently use both languages, may be protective against dementia. However, becoming bilingual in adulthood or using the second language infrequently is unlikely to substantially delay onset of the disease.

  11. Continuous retrieval of delayed Raman polaritons

    CERN Document Server

    Smartsev, Slava; Davidson, Nir; Firstenberg, Ofer

    2016-01-01

    We use a Raman four-wave mixing process to read out light from an atomic coherence which is continuously written. This realizes a continuous source of polaritons having been delayed or effectively stored for a finite duration. Contrary to slow-light delay, which depends on the atom number and population distribution, here the effective storage duration is determined solely by intensive properties of the system, approaching the ground-state natural lifetime at the weak driving limit. The generated polaritons are background free. We experimentally probe these properties utilizing spatial atomic diffusion as an 'internal clock' for the write-read delay. A continuous source of delayed polaritons can replace discrete write-read procedures when the atomic evolution is the subject of interest, for example, when dipolar interactions lead to retrieval of non-classical light.

  12. Monolithic Time Delay Integrated APD Arrays Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The overall goal of the proposed program by Epitaxial Technologies is to develop monolithic time delay integrated avalanche photodiode (APD) arrays with sensitivity...

  13. Delayed transverse radiation myelitis in esophageal carcinoma

    International Nuclear Information System (INIS)

    Objective: To investigate the prevention and treatment of delayed transverse myelitis caused by radiotherapy in patients with thoracic esophageal carcinoma. Methods: Radical radiotherapy had been given to five patients (female 3, male 2) with thoracic esophageal carcinoma with delayed transverse myelitis developed 7 to 30 months after radiotherapy without any local recurrence. The study was done in an attempt to describe the clinical symptoms and signs. Analysis of causes was done to seek possible means of treatment and prevention. Results: Once delayed transverse myelitis had happened, it was not possible to cure. In this group, four patients died 1-2 years after myelopathy had occurred, and one was alive with functional neurological loss. Conclusions: Delayed transverse myelitis is an uncommon and serious complication induced by irradiation. It is very difficult to manage and indicates a very poor prognosis. The authors recommend precise radiation design and prudent performance for prevention

  14. Internet end-to-end delay dynamics

    Institute of Scientific and Technical Information of China (English)

    Zhu Changhua; Pei Changxing; Li Jiandong; Chen Nan; Yi Yunhui

    2006-01-01

    End-to-end delay is one of the most important characteristics of Internet end-to-end packet dynamics, which can be applied to quality of services (QoS) management, service level agreement (SLA) management, congestion control algorithm development, etc. Nonstationarity and nonlinearity are found by the analysis of various delay series measured from different links. The fact that different types of links have different degree of Self-Similarity is also obtained. By constructing appropriate network architecture and neural functions, functional networks can be used to model the Internet end-to-end nonlinear delay time series. Furthermore, by using adaptive parameter studying algorithm, the nonstationarity can also be well modeled. The numerical results show that the provided functional network architecture and adaptive algorithm can precisely characterize the Internet end-to-end delay dynamics.

  15. Phase synchronization in time-delay systems.

    Science.gov (United States)

    Senthilkumar, D V; Lakshmanan, M; Kurths, J

    2006-09-01

    Though the notion of phase synchronization has been well studied in chaotic dynamical systems without delay, it has not been realized yet in chaotic time-delay systems exhibiting non-phase-coherent hyperchaotic attractors. In this paper we report identification of phase synchronization in coupled time-delay systems exhibiting hyperchaotic attractor. We show that there is a transition from nonsynchronized behavior to phase and then to generalized synchronization as a function of coupling strength. These transitions are characterized by recurrence quantification analysis, by phase differences based on a transformation of the attractors, and also by the changes in the Lyapunov exponents. We have found these transitions in coupled piecewise linear and in Mackey-Glass time-delay systems.

  16. Dry Mouth? Don't Delay Treatment

    Science.gov (United States)

    ... For Consumers Home For Consumers Consumer Updates Dry Mouth? Don't Delay Treatment Share Tweet Linkedin Pin ... saliva, cavities may occur. back to top Dry Mouth Treatments Your doctor or dentist may recommend oral ...

  17. Lensing Time Delays and Cosmological Complementarity

    CERN Document Server

    Linder, Eric V

    2011-01-01

    Time delays in strong gravitational lensing systems possess significant complementarity with distance measurements to determine the dark energy equation of state, as well as the matter density and Hubble constant. Time delays are most useful when observations permit detailed lens modeling and variability studies, requiring high resolution imaging, long time monitoring, and rapid cadence. We quantify the constraints possible between a sample of 150 such time delay lenses and a near term supernova program, such as might become available from an Antarctic telescope such as KDUST and the Dark Energy Survey. Adding time delay data to supernovae plus cosmic microwave background information can improve the dark energy figure of merit by almost a factor 5 and determine the matter density \\Omega_m to 0.004, Hubble constant h to 0.7%, and dark energy equation of state time variation w_a to 0.26, systematics permitting.

  18. Uranium Determination by Delayed Neutron Counting

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>Uranium is a very important resource in nuclear industry, especially in the exploiture of nuclear energy. Determination of uranium using delayed neutron counting (DNC) is simple, non-destructive, and

  19. Lauch of CERN particle accelerator delayed

    CERN Multimedia

    2007-01-01

    "Scientists seeking to uncover the secrets of the universe will have to wait a little longer after the CERN laboratory inSwitzerland yesterday confirmed a delay in tests of its massive new particle accelerator." (1 page)

  20. Interaction of Airspace Partitions and Traffic Flow Management Delay with Weather

    Science.gov (United States)

    Lee, Hak-Tae; Chatterji, Gano B.; Palopo, Kee

    2011-01-01

    The interaction of partitioning the airspace and delaying flights in the presence of convective weather is explored to study how re-partitioning the airspace can help reduce congestion and delay. Three approaches with varying complexities are employed to compute the ground delays.In the first approach, an airspace partition of 335 high-altitude sectors that is based on clear weather day traffic is used. Routes are then created to avoid regions of convective weather. With traffic flow management, this approach establishes the baseline with per-flight delay of 8.4 minutes. In the second approach, traffic flow management is used to select routes and assign departure delays such that only the airport capacity constraints are met. This results in 6.7 minutes of average departure delay. The airspace is then partitioned with a specific capacity. It is shown that airspace-capacity-induced delay can be reduced to zero ata cost of 20percent more sectors for the examined scenario.

  1. Intentional signals during saccadic and reaching delays in the human posterior parietal cortex.

    Science.gov (United States)

    Galati, Gaspare; Committeri, Giorgia; Pitzalis, Sabrina; Pelle, Gina; Patria, Fabiana; Fattori, Patrizia; Galletti, Claudio

    2011-12-01

    In the monkey posterior parietal cortex (PPC), there is clear evidence of anatomically segregated neuronal populations specialized for planning saccades and arm-reaching movements. However, functional neuroimaging studies in humans have yielded controversial results. Here we show that the human PPC contains distinct subregions responsive to salient visual cues, some of which combine spatial and action-related signals into 'intentional' signals. Participants underwent event-related functional magnetic resonance imaging while performing delayed saccades and long-range arm reaches instructed by visual cues. We focused on activity in the time period following the cue and preceding the actual movement. The use of individual cortical surface reconstructions with detailed sulcal labeling allowed the definition of six responsive regions with distinctive anatomical locations in the PPC. Each region exhibited a distinctive combination of transient and sustained signals during the delay, modulated by either the cue spatial location (contralateral vs. ipsilateral), the instructed action (saccades vs. reaching) or both. Importantly, a lateral and a medial dorsal parietal region showed sustained responses during the delay preferentially for contralateral saccadic and reaching trials, respectively. In the lateral region, preference for saccades was evident only as a more sustained response during saccadic vs. reaching delays, whereas the medial region also showed a higher transient response to cues signaling reaching vs. saccadic actions. These response profiles closely match the behavior of neurons in the macaque lateral and medial intraparietal area, respectively, and suggest that these corresponding human regions are encoding spatially directed action plans or 'intentions'.

  2. NONEL High Precision MS Delay Detonator

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The NONEL high precision MS Delay Detonator (FDG-1detonator) is introduced. The main aspects about the FDG-1 detonator include the choice of structure, delay composition, control of the gas chamber, o ptimum charge and density, suitable explosives per meter in the NONEL tube, base firing charge and the main specifications. The improvement of the characteristics of FDG-1 detonator has been tested systematical ly. The testing method is reliable and its precision can meet the dema nd for usage.

  3. Improvement of Delayed Neutron Counting System

    Institute of Scientific and Technical Information of China (English)

    YUAN; Guo-jun; XIAO; Cai-jin; YANG; Wei; ZHANG; Gui-ying; JIN; Xiang-chun; WANG; Ping-sheng; NI; Bang-fa

    2012-01-01

    <正>A new delayed neutron counting system, which is good at qualitative and quantitative analysis of fissionable nuclide mixture, will be established at China Advanced Research Reactor (CARR). We use 3 He proportional counters to count the delayed neutrons after the samples irradiated by reactor neutrons, including U3O8-stantard, uranium ore and enriched uranium. Then, the counting efficiency and limit of this system were calculated.

  4. Anharmonic resonances with recursive delay feedback

    OpenAIRE

    Goldobin, Denis S.

    2011-01-01

    We consider application of the multiple time delayed feedback for control of anharmonic (nonlinear) oscillators subject to noise. In contrast to the case of a single delay feedback, the multiple one exhibits resonances between feedback and nonlinear harmonics, leading to a resonantly strong or weak oscillation coherence even for a small anharmonicity. Analytical results are confirmed numerically for van der Pol and van der Pol-Duffing oscillators. Highlights: > We construct general theory of ...

  5. Delayed stoma formation in Fournier's gangrene.

    Science.gov (United States)

    Bronder, C S; Cowey, A; Hill, J

    2004-11-01

    Fournier's gangrene is traditionally treated with prompt surgical debridement and in many cases a diverting colostomy is also fashioned during the same procedure. We present four cases where stoma formation was delayed until the second look procedure. The physiological states at the time of either procedure were compared using POSSUM. The results showed an improvement in the physiological condition in all patients at the time of the second operation, suggesting that a delay can potentially improve prognosis in such cases. PMID:15521946

  6. Nursing diagnosis of delayed surgical recovery

    OpenAIRE

    Rosimere Ferreira Santana; Tallita Mello Delphino; Nathalia Martins Henriques; Priscilla Alfradique de Souza; Thais da Silva Soares; Shimmenes Kamacael Pereira

    2014-01-01

    The purpose of this study was to identify and analyze the nursing diagnosis of delayed surgical recovery, its defining characteristics and related factors according to NANDA-I taxonomy, through an integrative review. 34 articles were selected from MEDLINE, CINAHL, LILACS, and BDENF databases. In these, the delayed surgical recovery diagnosis was identified in a study. However, it was possible to identify the defining characteristics: difficulty to move about (36.4%) which requires help to com...

  7. Delay in diagnosis of congenital anal stenosis

    OpenAIRE

    Weledji, Elroy P; Motaze Sinju

    2016-01-01

    Although a minor anorectal malformation the delay in diagnosis and treatment of anal stenosis may result in significant early or late complications. Early inspection of the perineum in the neonate to pick up and correct anorectal malformation improves long term outcome but this requires proper anal examination or it could be missed. We present and discuss a case of delayed diagnosis of congenital anal stenosis (a low anorectal anomaly) with an imminent colonic perforation. Severe anal stenosi...

  8. Difference methods for stiff delay differential equations

    International Nuclear Information System (INIS)

    Delay differential equations of the form y'(t) = f(y(t), z(t)), where z(t) = [y1(α1(y(t))),..., y/sub n/(α/sub n/(y(t)))]/sup T/ and α/sub i/(y(t)) less than or equal to t, arise in many scientific and engineering fields when transport lags and propagation times are physically significant in a dynamic process. Difference methods for approximating the solution of stiff delay systems require special stability properties that are generalizations of those employed for stiff ordinary differential equations. By use of the model equation y'(t) = py(t) + qy(t-1), with complex p and q, the definitions of A-stability, A( )-stability, and stiff stability have been generalize to delay equations. For linear multistep difference formulas, these properties extend directly from ordinary to delay equations. This straight forward extension is not true for implicit Runge-Kutta methods, as illustrated by the midpoint formula, which is A-stable for ordinary equations, but not for delay equations. A computer code for stiff delay equations was developed using the BDF. 24 figures, 5 tables

  9. Introduction to attosecond delays in photoionization

    International Nuclear Information System (INIS)

    This tutorial presents an introduction to the interaction of light and matter on the attosecond timescale. Our aim is to detail the theoretical description of ultra-short time delays and to relate these to the phase of extreme ultraviolet (XUV) light pulses and to the asymptotic phaseshifts of photoelectron wave packets. Special emphasis is laid on time-delay experiments, where attosecond XUV pulses are used to photoionize target atoms at well-defined times, followed by a probing process in real time by a phase-locked, infrared laser field. In this way, the laser field serves as a ‘clock’ to monitor the ionization event, but the observable delays do not correspond directly to the delay associated with single-photon ionization. Instead, a significant part of the observed delay originates from a measurement induced process, which obscures the single-photon ionization dynamics. This artefact is traced back to a phaseshift of the above-threshold ionization transition matrix element, which we call the continuum-continuum phase. It arises due to the laser-stimulated transitions between Coulomb continuum states. As we shall show here, these measurement-induced effects can be separated from the single-photon ionization process, using analytical expressions of universal character, so that eventually the attosecond time delays in photoionization can be accessed.

  10. Additives in swine nutrition

    Directory of Open Access Journals (Sweden)

    Sinovec Zlatan J.

    2002-01-01

    Full Text Available To attain better feed utilization, longer preservation, easier manipultion and higher production and better quality of food of animal orgin as the final goal, besides raw materials, feed mixes contain numerous pronutrients (additives, added to perform different effects, in a narrower sense, the term pronutrient implies heterogenous substances, which have no diverse effects and have to be efficient in the manner of use. Basically, all pronutrients have to reach the goal of keeping optimal animal health status and to increase production of food of animal origin without adverse and negative effects. The development of biotechnology had a great part in the appearance of natural alternatives which are able to fulfil and satisfy the high demands of highly productive animals, as well as those of the consumer lobby and environmental protection movements. Growth promoters based upon physiological mechanisms and production potential of the animal have an unquestionable adventage, not only because of the lack of residues in food of animal origin; but also because of their ecological safety and decrease of envirnomental pollution by undigested materials. Demand continues to grow for "all natural", non-pharmaceutical feed additives with growth enhancing effects in food animals. Special attention is paid to minerals (anorganic and organic sources, growth stimulators (antibiotics, probiotics prebiotics, substances for better feed utilization (enzymes, acidifers adsorbents.

  11. Optimal Control with Time Delays via the Penalty Method

    Directory of Open Access Journals (Sweden)

    Mohammed Benharrat

    2014-01-01

    Full Text Available We prove necessary optimality conditions of Euler-Lagrange type for a problem of the calculus of variations with time delays, where the delay in the unknown function is different from the delay in its derivative. Then, a more general optimal control problem with time delays is considered. Main result gives a convergence theorem, allowing us to obtain a solution to the delayed optimal control problem by considering a sequence of delayed problems of the calculus of variations.

  12. Delay-dependent H-infinity control for continuous time-delay systems via state feedback

    Institute of Scientific and Technical Information of China (English)

    Xinchun JIA; Yibo GAO; Jingmei ZHANG; Nanning ZHENG

    2007-01-01

    The delay-dependent H-infinity analysis and H-infinity control problems for continuous time-delay systems are studied. By introducing an equality with some free weighting matrices, an improved criterion of delay-dependent stability with H-infinity performance for such systems is presented, and a criterion of existence and some design methods of delay-dependent H-infinity controller for such systems are proposed in term of a set of matrix inequalities, which is solved efficiently by an iterative algorithm. Further, the corresponding results for the delay-dependent robust H-infinity analysis and robust H-infinity control problems for continuous time-delay uncertain systems are given. Finally, two numerical examples are given to illustrate the efficiency of the proposed method by comparing with the other existing results.

  13. Simultaneous Estimation of Time Delays and Quasar Structure

    Science.gov (United States)

    Morgan, Christopher W.; Eyler, Michael E.; Kochanek, C. S.; Morgan, Nicholas D.; Falco, Emilio E.; Vuissoz, C.; Courbin, F.; Meylan, G.

    2008-03-01

    We expand our Bayesian Monte Carlo method for analyzing the light curves of gravitationally lensed quasars to simultaneously estimate time delays and the sizes of quasar continuum emission regions including their mutual uncertainties. We apply the method to HE1104-1805 and QJ0158-4325, two doubly imaged quasars with microlensing and intrinsic variability on comparable timescales. For HE1104-1805 the resulting time delay of Δ tAB = tA - tB = 162.2-5.9+6.3 days and accretion disk size estimate of log {(rs/cm) [cos (i)/0.5]1/2} = 15.7-0.5+0.4 at 0.2 μm in the rest frame and for inclination i are consistent with earlier estimates but suggest that existing methods for estimating time delays in the presence of microlensing underestimate the uncertainties. We are unable to measure a time delay for QJ0158-4325, but the accretion disk size is log {(rs/cm) [cos (i)/0.5]1/2} = 14.9 +/- 0.3 at 0.3 μm in the rest frame. Based on observations obtained with the Small and Moderate Aperture Research Telescope System (SMARTS) 1.3 m, which is operated by the SMARTS Consortium, and observations made with the NASA/ESA Hubble Space Telescope for program HST-GO-9744 of the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555.

  14. A Boolean delay equation model of ENSO variability

    Science.gov (United States)

    Saunders, Amira; Ghil, Michael

    2001-12-01

    Boolean delay equations (BDEs) provide a mathematical framework to formulate and analyze conceptual models of complex multi-component systems. This framework is used here to construct a simple conceptual model for the El-Niño/Southern Oscillation (ENSO) phenomenon. ENSO involves the coupling of atmospheric and oceanic processes that are far from being completely understood. Our BDE model uses Boolean variables to represent key atmospheric and oceanic quantities and equations that involve logical operators to describe their evolution. Two distinct time-delay parameters, one for the local atmosphere-ocean coupling effects and the other for oceanic wave propagation, are introduced. Over a range of physically relevant delay values, this truly minimal model captures two essential features of ENSO’s interannual variability - its regularity and its tendency to phase-lock to the annual cycle. Oscillations with average cycle length that is an integer multiple of the seasonal cycle are prevalent and range from 2 to 7 years. Transition zones - where the average period lengths are noninteger rational multiples of the forcing period - exhibit Devil’s staircases, a signature of the quasi-periodic (QP) route to chaos. Our BDE model thus validates results from previous studies of the interaction of the seasonal cycle with ENSO’s “delayed oscillator”. It gives therewith support to the view that the observed irregularity results predominantly from low-order chaotic processes rather than from stochastic weather noise. Moreover, in the transition zone between the two integer periodicities of 2 and 3 years, a heretofore unsuspected, self-similar “fractal sunburst” pattern emerges in phase-parameter space. This pattern provides a distinct and more complex scenario than the QP route to chaos found in earlier, more detailed ENSO models. Period selection in this 2-3-year transitional region seems to play a key role in ENSO’s irregularity, as well as in the appearance of

  15. Analysis of ion dynamics and peak shapes for delayed extraction time-of-flight mass spectrometers

    Science.gov (United States)

    Collado, V. M.; Ponciano, C. R.; Fernandez-Lima, F. A.; da Silveira, E. F.

    2004-06-01

    The dependence of time-of-flight (TOF) peak shapes on time-dependent extraction electric fields is studied theoretically. Conditions for time focusing are analyzed both analytically and numerically for double-acceleration-region TOF spectrometers. Expressions for the spectrometer mass resolution and for the critical delay time are deduced. Effects due to a leakage field in the first acceleration region are shown to be relevant under certain conditions. TOF peak shape simulations for the delayed extraction method are performed for emitted ions presenting a Maxwellian initial energy distribution. Calculations are compared to experimental results of Cs+ emission due to CsI laser ablation.

  16. Time delay induced different synchronization patterns in repulsively coupled chaotic oscillators.

    Science.gov (United States)

    Yao, Chenggui; Yi, Ming; Shuai, Jianwei

    2013-09-01

    Time delayed coupling plays a crucial role in determining the system's dynamics. We here report that the time delay induces transition from the asynchronous state to the complete synchronization (CS) state in the repulsively coupled chaotic oscillators. In particular, by changing the coupling strength or time delay, various types of synchronous patterns, including CS, antiphase CS, antiphase synchronization (ANS), and phase synchronization, can be generated. In the transition regions between different synchronous patterns, bistable synchronous oscillators can be observed. Furthermore, we show that the time-delay-induced phase flip bifurcation is of key importance for the emergence of CS. All these findings may light on our understanding of neuronal synchronization and information processing in the brain.

  17. HOPF BIFURCATION OF AN OSCILLATOR WITH QUADRATIC AND CUBIC NONLINEARITIES AND WITH DELAYED VELOCITY FEEDBACK

    Institute of Scientific and Technical Information of China (English)

    WANG Huailei; WANG Zaihua; HU Haiyan

    2004-01-01

    This paper studies the local dynamics of an SDOF system with quadratic and cubic stiffness terms, and with linear delayed velocity feedback. The analysis indicates that for a sufficiently large velocity feedback gain, the equilibrium of the system may undergo a number of stability switches with an increase of time delay, and then becomes unstable forever. At each critical value of time delay for which the system changes its stability, a generic Hopf bifurcation occurs and a periodic motion emerges in a one-sided neighbourhood of the critical time delay. The method of Fredholm alternative is applied to determine the bifurcating periodic motions and their stability. It stresses on the effect of the system parameters on the stable regions and the amplitudes of the bifurcating periodic solutions.

  18. Design of a Novel Current Balanced Voltage Controlled Delay Element

    Directory of Open Access Journals (Sweden)

    Pooja Saxena

    2014-04-01

    Full Text Available This paper presents a design of fast voltage controlled delay element based on modified version of low noise Current Balanced Logic (CBL. This delay element provides identical rising and falling edge delays controlled by the single control voltage. The post layout tunable delay range is from 140 ps to 800 ps over control voltage range of 0 to 2.1 V. An analysis for the delay element is also presented, which is in agreement with the simulated delays. A Delay Lock Loop (DLL is designed using this delay element to verify its performance.

  19. Delay-dependent guaranteed cost control for uncertain systems with both state and input delays

    Institute of Scientific and Technical Information of China (English)

    Xuanfang YANG; Wuhua CHEN; Huajing FANG

    2004-01-01

    This paper considers the guaranteed cost control problem for a class of uncertain linear systems with both state and input delays.By representing the time-delay system in the descriptor system form and using a recent result on bounding of cross products of vectors,we obtain new delay-dependent sufficient conditions for the existence of the guaranteed cost controller in terms of linear matrix inequalities.Two examples are presented which show the effectiveness of our approach.

  20. Delay dependent stability criteria for recurrent neural networks with time varying delays

    Institute of Scientific and Technical Information of China (English)

    Zhanshan WANG; Huaguang ZHANG

    2009-01-01

    This paper aims to present some delay-dependent global asymptotic stability criteria for recurrent neural networks with time varying delays.The obtained results have no restriction on the magnitude of derivative of time varying delay,and can be easily checked due to the form of linear matrix inequality.By comparison with some previous results,the obtained results are less conservative.A numerical example is utilized to demonstrate the effectiveness of the obtained results.

  1. Network Effects, Congestion Externalities, and Air Traffic Delays: Or Why All Delays Are Not Evil

    OpenAIRE

    Christopher Mayer; Todd Sinai

    2002-01-01

    We examine two factors that might explain the extent of air traffic delays in the United States: network benefits due to hubbing and congestion externalities. Airline hubs enable passengers to cross-connect to many destinations, thus creating network benefits that increase in the number of markets served from the hub. Delays are the equilibrium outcome of a hub airline equating high marginal benefits from hubbing with the marginal cost of delays. Congestion externalities are created when airl...

  2. Improving Delay-Range-Dependent Stability Condition for Systems with Interval Time-Varying Delay

    Directory of Open Access Journals (Sweden)

    Wei Qian

    2013-01-01

    Full Text Available This paper discusses the delay-range-dependent stability for systems with interval time-varying delay. Through defining the new Lyapunov-Krasovskii functional and estimating the derivative of the LKF by introducing new vectors, using free matrices and reciprocally convex approach, the new delay-range-dependent stability conditions are obtained. Two well-known examples are given to illustrate the less conservatism of the proposed theoretical results.

  3. Apparatus and Method for Compensating for Process, Voltage, and Temperature Variation of the Time Delay of a Digital Delay Line

    Science.gov (United States)

    Seefeldt, James (Inventor); Feng, Xiaoxin (Inventor); Roper, Weston (Inventor)

    2013-01-01

    A process, voltage, and temperature (PVT) compensation circuit and a method of continuously generating a delay measure are provided. The compensation circuit includes two delay lines, each delay line providing a delay output. The two delay lines may each include a number of delay elements, which in turn may include one or more current-starved inverters. The number of delay lines may differ between the two delay lines. The delay outputs are provided to a combining circuit that determines an offset pulse based on the two delay outputs and then averages the voltage of the offset pulse to determine a delay measure. The delay measure may be one or more currents or voltages indicating an amount of PVT compensation to apply to input or output signals of an application circuit, such as a memory-bus driver, dynamic random access memory (DRAM), a synchronous DRAM, a processor or other clocked circuit.

  4. Advanced access: reducing waiting and delays in primary care.

    Science.gov (United States)

    Murray, Mark; Berwick, Donald M

    2003-02-26

    Delay of care is a persistent and undesirable feature of current health care systems. Although delay seems to be inevitable and linked to resource limitations, it often is neither. Rather, it is usually the result of unplanned, irrational scheduling and resource allocation. Application of queuing theory and principles of industrial engineering, adapted appropriately to clinical settings, can reduce delay substantially, even in small practices, without requiring additional resources. One model, sometimes referred to as advanced access, has increasingly been shown to reduce waiting times in primary care. The core principle of advanced access is that patients calling to schedule a physician visit are offered an appointment the same day. Advanced access is not sustainable if patient demand for appointments is permanently greater than physician capacity to offer appointments. Six elements of advanced access are important in its application balancing supply and demand, reducing backlog, reducing the variety of appointment types, developing contingency plans for unusual circumstances, working to adjust demand profiles, and increasing the availability of bottleneck resources. Although these principles are powerful, they are counter to deeply held beliefs and established practices in health care organizations. Adopting these principles requires strong leadership investment and support.

  5. Advanced access: reducing waiting and delays in primary care.

    Science.gov (United States)

    Murray, Mark; Berwick, Donald M

    2003-02-26

    Delay of care is a persistent and undesirable feature of current health care systems. Although delay seems to be inevitable and linked to resource limitations, it often is neither. Rather, it is usually the result of unplanned, irrational scheduling and resource allocation. Application of queuing theory and principles of industrial engineering, adapted appropriately to clinical settings, can reduce delay substantially, even in small practices, without requiring additional resources. One model, sometimes referred to as advanced access, has increasingly been shown to reduce waiting times in primary care. The core principle of advanced access is that patients calling to schedule a physician visit are offered an appointment the same day. Advanced access is not sustainable if patient demand for appointments is permanently greater than physician capacity to offer appointments. Six elements of advanced access are important in its application balancing supply and demand, reducing backlog, reducing the variety of appointment types, developing contingency plans for unusual circumstances, working to adjust demand profiles, and increasing the availability of bottleneck resources. Although these principles are powerful, they are counter to deeply held beliefs and established practices in health care organizations. Adopting these principles requires strong leadership investment and support. PMID:12597760

  6. Vulnerability for mania - is it linked to problems delaying gratification?

    Science.gov (United States)

    Meyer, Thomas D; Newman, Antonia L; Jordan, Gabriele

    2015-09-30

    Impulsivity is described as one of the main risk factors for mania. One facet of impulsivity, the inability to delay gratification, might be of special relevance, because a hypersensitivity to reward is hypothesized to be related to mania. The main aim of this study was to examine whether risk for mania is associated with deficits in the ability to delay gratification using both a behavioral and a self-report (UPPS) measure. An additional reason for choosing the UPPS was to see if prior results about an association between risk for mania and positive urgency could be replicated. Thirty-three individuals at risk for mania and a matched control group were selected using the Hypomanic Personality Scale and interviewed for a history of mood disorders. The main outcome measures were the Single-Key-Impulsivity-Paradigm and Monetary Choice Questionnaire. The groups did not differ in measures of gratification delay but we replicated other studies reporting significantly higher levels of positive urgency and sensation seeking in at-risk individuals. We suggest that individuals at risk might not generally be more impulsive but rather that impulsive behaviors might be triggered in response to specific mood states. PMID:26160207

  7. Additive Pattern Database Heuristics

    CERN Document Server

    Felner, A; Korf, R E; 10.1613/jair.1480

    2011-01-01

    We explore a method for computing admissible heuristic evaluation functions for search problems. It utilizes pattern databases, which are precomputed tables of the exact cost of solving various subproblems of an existing problem. Unlike standard pattern database heuristics, however, we partition our problems into disjoint subproblems, so that the costs of solving the different subproblems can be added together without overestimating the cost of solving the original problem. Previously, we showed how to statically partition the sliding-tile puzzles into disjoint groups of tiles to compute an admissible heuristic, using the same partition for each state and problem instance. Here we extend the method and show that it applies to other domains as well. We also present another method for additive heuristics which we call dynamically partitioned pattern databases. Here we partition the problem into disjoint subproblems for each state of the search dynamically. We discuss the pros and cons of each of these methods a...

  8. Perspectives on Additive Manufacturing

    Science.gov (United States)

    Bourell, David L.

    2016-07-01

    Additive manufacturing (AM) has skyrocketed in visibility commercially and in the public sector. This article describes the development of this field from early layered manufacturing approaches of photosculpture, topography, and material deposition. Certain precursors to modern AM processes are also briefly described. The growth of the field over the last 30 years is presented. Included is the standard delineation of AM technologies into seven broad categories. The economics of AM part generation is considered, and the impacts of the economics on application sectors are described. On the basis of current trends, the future outlook will include a convergence of AM fabricators, mass-produced AM fabricators, enabling of topology optimization designs, and specialization in the AM legal arena. Long-term developments with huge impact are organ printing and volume-based printing.

  9. Sarks as additional fermions

    Science.gov (United States)

    Agrawal, Jyoti; Frampton, Paul H.; Jack Ng, Y.; Nishino, Hitoshi; Yasuda, Osamu

    1991-03-01

    An extension of the standard model is proposed. The gauge group is SU(2) X ⊗ SU(3) C ⊗ SU(2) S ⊗ U(1) Q, where all gauge symmetries are unbroken. The colour and electric charge are combined with SU(2) S which becomes strongly coupled at approximately 500 GeV and binds preons to form fermionic and vector bound states. The usual quarks and leptons are singlets under SU(2) X but additional fermions, called sarks. transform under it and the electroweak group. The present model explains why no more than three light quark-lepton families can exist. Neutral sark baryons, called narks, are candidates for the cosmological dark matter having the characteristics designed for WIMPS. Further phenomenological implications of sarks are analyzed i including electron-positron annihilation. Z 0 decay, flavor-changing neutral currents. baryon-number non-conservation, sarkonium and the neutron electric dipole moment.

  10. Delayed Hopf bifurcation in time-delayed slow-fast systems

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    This paper presents an investigation on the phenomenon of delayed bifurcation in time-delayed slow-fast differential systems.Here the two delayed’s have different meanings.The delayed bifurcation means that the bifurcation does not happen immediately at the bifurcation point as the bifurcation parameter passes through some bifurcation point,but at some other point which is above the bifurcation point by an obvious distance.In a time-delayed system,the evolution of the system depends not only on the present state but also on past states.In this paper,the time-delayed slow-fast system is firstly simplified to a slow-fast system without time delay by means of the center manifold reduction,and then the so-called entry-exit function is defined to characterize the delayed bifurcation on the basis of Neishtadt’s theory.It shows that delayed Hopf bifurcation exists in time-delayed slow-fast systems,and the theoretical prediction on the exit-point is in good agreement with the numerical calculation,as illustrated in the two illustrative examples.

  11. Time-Delay Estimation using the Characteristic Roots of Delay Differential Equations

    Directory of Open Access Journals (Sweden)

    Sun Yi

    2012-01-01

    Full Text Available Problem statement: For ordinary dynamic systems (i.e., non-delayed, various methods such as linear least-squares, gradient-weighted least-squares, Kalman filtering and other robust techniques have been widely used in signal processing, robotics, civil engineering. On the other hand, time-delay estimation of systems with unknown time-delay is still a challenging problem due to difficulty in formulation caused. Approach: The presented method makes use of the Lambert W function and analytical solutions of scalar first-order Delay Differential Equations (DDEs. The Lambert W function has been known to be useful in solving delay differential equations. From the solutions in terms of the Lambert W function, the dominant characteristic roots can be obtained and used to estimate time-delays. The function is already embedded in various software packages (e.g., MATLAB and thus, the presented method can be readily used for time-delay systems. Results: The presented method and the provided examples show ease of formulation and accuracy of time-delay estimation. Conclusion: Estimation of time-delays can be conducted in an analytical way. The presented method will be extended to general systems of DDEs and application to physical systems.

  12. Multivariate Markov processes for stochastic systems with delays: application to the stochastic Gompertz model with delay.

    Science.gov (United States)

    Frank, T D

    2002-07-01

    Using the method of steps, we describe stochastic processes with delays in terms of Markov diffusion processes. Thus, multivariate Langevin equations and Fokker-Planck equations are derived for stochastic delay differential equations. Natural, periodic, and reflective boundary conditions are discussed. Both Ito and Stratonovich calculus are used. In particular, our Fokker-Planck approach recovers the generalized delay Fokker-Planck equation proposed by Guillouzic et al. The results obtained are applied to a model for population growth: the Gompertz model with delay and multiplicative white noise.

  13. Impulsive control of time-delay systems using delayed impulse and its application to impulsive master-slave synchronization

    Energy Technology Data Exchange (ETDEWEB)

    Sun Jitao [Department of Mathematics, Tongji University, Shanghai 200092 (China); Centre for Intelligent and Networked Systems, Central Queensland University, Rockhampton Qld 4702 (Australia); Han Qinglong [Centre for Intelligent and Networked Systems, Central Queensland University, Rockhampton Qld 4702 (Australia); School of Computing Sciences, Central Queensland University, Rockhampton Qld 4702 (Australia)], E-mail: q.han@cqu.edu.au; Jiang Xiefu [Centre for Intelligent and Networked Systems, Central Queensland University, Rockhampton Qld 4702 (Australia); School of Automation, Hangzhou Dianzi University, Hangzhou 310018, Zhejiang (China)

    2008-10-13

    This Letter is concerned with impulsive control of a class of nonlinear time-delay systems. Some uniform stability criteria for the closed-loop time-delay system under delayed impulsive control are derived by using piecewise Lyapunov functions. Then the criteria are applied to impulsive master-slave synchronization of some secure communication systems with transmission delays and sample delays under delayed impulsive control. Two numerical examples are given to illustrate the effectiveness of the derived results.

  14. PET/CT imaging of delayed radiation encephalopathy following radiotherapy for nasopharyngeal carcinoma

    Institute of Scientific and Technical Information of China (English)

    WANG Xin-lu; YIN Ji-lin; LI Hua; LI Xiang-dong; QUAN Jiang-tao

    2007-01-01

    Background With the significant improvement in the survival of patients with nasopharyngeal carcinoma (NPC)undergoing radiotherapy and the growing availability of the sophisticated imaging modalities, the number of radiation encephalopathy (RE) cases relating to NPC radiotherapy is increasing. In this study, we investigated the metabolic and density changes of the compromised brain tissues during delayed RE using a positron-emission tomography-computed tomography (PET/CT) to provide clinical evidences for the diagnosis of delayed RE following radiotherapy for NPC.Methods The PET/CT manifestations and the clinical data of 53 pathologically confirmed NPC patients with delayed RE following radical radiotherapy and 15 healthy volunteers were investigated. The standardized uptake values (SUV) of the bilateral temporal lobes, the occipital lobe and the brain stem were measured respectively; and then the metabolic reduction rate of 88 temporal lobes and 13 brain stems were calculated for a statistical comparison between the two groups.Results The earliest case of delayed RE in the investigated patients occurred 1.5 years after radiotherapy. Delayed RE frequently involved the inferior temporal lobe. For patients with delayed RE confirmed by clinical symptoms and imaging findings, PET maintained a 100% coincidence rate with CT; however, in the 25 temporal lobes of the 35 delayed RE patients, PET revealed obvious hypometabolic changes whereas CT displayed normal density. The incidence of brain stem metabolic reductions was 24.5% (13/53) in the investigated patients, including 4 patients with hypometabolic changes shown by PET and negative finding shown by CT. The incidence of granuloma adjacent to the hypometabolic region in the temporal lobe was 12.5% (11/88).Conclusion Delayed RE patients exhibit significant hypometabolic changes in the inferior temporal lobe, captured by PET much earlier than by CT. PET/CT offers a valuable means for the diagnosis of delayed RE in

  15. Effect of Phase Response Curve Skew on Synchronization with and without Conduction Delays

    Directory of Open Access Journals (Sweden)

    Carmen eCanavier

    2013-12-01

    Full Text Available A central problem in cortical processing including sensory binding and attentional gating is how neurons can synchronize their responses with zero or near-zero time lag. For a spontaneously firing neuron, an input from another neuron can delay or advance the next spike by different amounts depending upon the timing of the input relative to the previous spike. This information constitutes the phase response curve (PRC. We present a simple graphical method for determining the effect of PRC shape on synchronization tendencies and illustrate it using type 1 PRCs, which consist entirely of advances (delays in response to excitation (inhibition. We obtained the following generic solutions for type 1 PRCs, which include the pulse coupled leaky integrate and fire model. For pairs with mutual excitation, exact synchrony can be stable for strong coupling because of the stabilizing effect of the causal limit region of the PRC in which an input triggers a spike immediately upon arrival. However, synchrony is unstable for short delays, because delayed inputs arrive during a refractory period and cannot trigger an immediate spike. Right skew destabilizes antiphase and enables modes with time lags that grow as the conduction delay is increased. Therefore, right skew favors near-synchrony at short conduction delays and a gradual transition between synchrony and antiphase for pairs coupled by mutual excitation. For pairs with mutual inhibition, zero time lag synchrony is stable for conduction delays ranging from zero to a substantial fraction of the period for pairs. However, for right skew there is a preferred antiphase mode at short delays. In contrast to mutual excitation, left skew destabilizes antiphase for mutual inhibition so that synchrony dominates at short delays as well. These pairwise synchronization tendencies constrain the synchronization properties of neurons embedded in larger networks.

  16. Tropospheric delay determination by Kalman filtering VLBI data

    Science.gov (United States)

    Soja, Benedikt; Nilsson, Tobias; Karbon, Maria; Zus, Florian; Dick, Galina; Deng, Zhiguo; Wickert, Jens; Heinkelmann, Robert; Schuh, Harald

    2015-09-01

    The troposphere is one of the most important error sources for space geodetic techniques relying on radio signals. Since it is not possible to model the wet part of the tropospheric delay with sufficient accuracy, it needs to be estimated from the observational data. In the analysis of very long baseline interferometry (VLBI) data, the parameter estimation is routinely performed using a least squares adjustment. In this paper, we investigate the application of a Kalman filter for parameter estimation, specifically focusing on the tropospheric delays. The main advantages of a Kalman filter are its real-time capability and stochastic approach. We focused on the latter and derived stochastic models for VLBI zenith wet delays, taking into account temporal and location-based differences. Compared to a static noise model, the quality of station coordinates, also estimated in the Kalman filter, increased as a result. In terms of baseline length and station coordinate repeatabilities, this improvement amounted to 2.3 %. Additionally, we compared the Kalman filter and least squares results for VLBI with zenith wet delays derived from GPS (Global Positioning System), water vapor radiometers, and ray tracing in numerical weather models. The agreement of the Kalman filter VLBI solution with respect to water vapor radiometer data was larger than that of the least squares solution by 6-15 %. Our investigations are based on selected VLBI data (CONT campaigns) that are closest to how future VLBI infrastructure is designed to operate. With the aim for continuous and near real-time parameter estimation and the promising results which we have achieved in this study, we expect Kalman filtering to grow in importance in VLBI analysis.

  17. Engineering Sensorial Delay to Control Phototaxis and Emergent Collective Behaviors

    Science.gov (United States)

    Mijalkov, Mite; McDaniel, Austin; Wehr, Jan; Volpe, Giovanni

    2016-01-01

    Collective motions emerging from the interaction of autonomous mobile individuals play a key role in many phenomena, from the growth of bacterial colonies to the coordination of robotic swarms. For these collective behaviors to take hold, the individuals must be able to emit, sense, and react to signals. When dealing with simple organisms and robots, these signals are necessarily very elementary; e.g., a cell might signal its presence by releasing chemicals and a robot by shining light. An additional challenge arises because the motion of the individuals is often noisy; e.g., the orientation of cells can be altered by Brownian motion and that of robots by an uneven terrain. Therefore, the emphasis is on achieving complex and tunable behaviors from simple autonomous agents communicating with each other in robust ways. Here, we show that the delay between sensing and reacting to a signal can determine the individual and collective long-term behavior of autonomous agents whose motion is intrinsically noisy. We experimentally demonstrate that the collective behavior of a group of phototactic robots capable of emitting a radially decaying light field can be tuned from segregation to aggregation and clustering by controlling the delay with which they change their propulsion speed in response to the light intensity they measure. We track this transition to the underlying dynamics of this system, in particular, to the ratio between the robots' sensorial delay time and the characteristic time of the robots' random reorientation. Supported by numerics, we discuss how the same mechanism can be applied to control active agents, e.g., airborne drones, moving in a three-dimensional space. Given the simplicity of this mechanism, the engineering of sensorial delay provides a potentially powerful tool to engineer and dynamically tune the behavior of large ensembles of autonomous mobile agents; furthermore, this mechanism might already be at work within living organisms such as

  18. Dietary approaches that delay age-related diseases.

    Science.gov (United States)

    Everitt, Arthur V; Hilmer, Sarah N; Brand-Miller, Jennie C; Jamieson, Hamish A; Truswell, A Stewart; Sharma, Anita P; Mason, Rebecca S; Morris, Brian J; Le Couteur, David G

    2006-01-01

    Reducing food intake in lower animals such as the rat decreases body weight, retards many aging processes, delays the onset of most diseases of old age, and prolongs life. A number of clinical trials of food restriction in healthy adult human subjects running over 2-15 years show significant reductions in body weight, blood cholesterol, blood glucose, and blood pressure, which are risk factors for the development of cardiovascular disease and diabetes. Lifestyle interventions that lower energy balance by reducing body weight such as physical exercise can also delay the development of diabetes and cardiovascular disease. In general, clinical trials are suggesting that diets high in calories or fat along with overweight are associated with increased risk for cardiovascular disease, type 2 diabetes, some cancers, and dementia. There is a growing literature indicating that specific dietary constituents are able to influence the development of age-related diseases, including certain fats (trans fatty acids, saturated, and polyunsaturated fats) and cholesterol for cardiovascular disease, glycemic index and fiber for diabetes, fruits and vegetables for cardiovascular disease, and calcium and vitamin D for osteoporosis and bone fracture. In addition, there are dietary compounds from different functional foods, herbs, and neutraceuticals such as ginseng, nuts, grains, and polyphenols that may affect the development of age-related diseases. Long-term prospective clinical trials will be needed to confirm these diet-disease relationships. On the basis of current research, the best diet to delay age-related disease onset is one low in calories and saturated fat and high in wholegrain cereals, legumes, fruits and vegetables, and which maintains a lean body weight. Such a diet should become a key component of healthy aging, delaying age-related diseases and perhaps intervening in the aging process itself. Furthermore, there are studies suggesting that nutrition in childhood and

  19. Stochastic Resonance in a Time-Delayed Bistable System Driven by Square-Wave Signal

    Institute of Scientific and Technical Information of China (English)

    GUO Feng; ZHOU Yu-Rong; ZHANG Yu

    2010-01-01

    @@ Stochastic resonance in a time-delayed bistable system subject to asymmetric dichotomous noise and multiplica-tire and additive white noise is investigated.Using small time delay approximation,we obtain the expression of the signal-to-noise ratio (SNR).It is found that the SNR is a non-monotonic function of the delayed times,of the amplitude of the input square-wave signal,as well as of the asymmetry of the dichotomous noise.In addition,the SNR varies non-monotonously with the system parameters,with the intensities of the multiplicative and additive noise,as well as with the correlate rate of the dichotomous noise.

  20. β-delayed proton decays near the proton drip line

    Institute of Scientific and Technical Information of China (English)

    XU; Shuwei; LI; Zhankui; XIE; Yuanxiang; HUANG; Wenxue; SH

    2005-01-01

    We briefly reviewed the experimental study on β-delayed proton decays near the proton drip line published by our group during the period of 1996―2004, namely the first observation of the β-delayed proton decays of 9 new nuclides in the rare-earth region and the new measurements of β-delayed proton decays of 5 nuclides in the mass (90 region near the N = Z line with the aid of the "p-γ" coincidence in combination with a He-jet tape transport system. In the meantime some important experimental technique details were supplemented. The experimental results, including the half-lives, spins, parities, deformations and production reaction cross sections for the 14 nuclei were summarized and compared with the current nuclear-model predictions, and then the following points were represented. (1) The experimental half-lives for 85Mo and 92Rh as well as the predicted "waiting point" nuclei 89Ru and 93Pd are 5―10 times longer than the theoretical predictions given by M(o)ller et al. using a macroscopic-microscopic model. It considerably influences the predictions of the abundances of the nuclides produced in the rp-process. (2) The current-model predictions are not consistent with the experimental assignments of the spins and parities for the proton drip-line nuclei 142Ho and 128Pm. However, the nuclear potential energy surface (PES) calculated by using a Woods- Saxon-Strutinsky method reproduced the experimental results. (3) The Alice code overestimated the production reaction cross sections of the studied 9 rare-earth nuclei by one order of magnitude or two, while HIVAP code overestimated them by one order of magnitude approximately.

  1. The delay effect on outcome evaluation: results from an Event-related Potential study

    Directory of Open Access Journals (Sweden)

    Chen eQu

    2013-11-01

    Full Text Available Behavioral studies demonstrate that the timing of receiving gains or losses affects decision-making, a phenomenon known as temporal discounting, as participants are inclined to prefer immediate rewards over delayed ones and vice versa for losses. The present study used the event-related potential (ERP technique with a simple gambling task to investigate how delayed rewards and losses affected the brain activity in outcome evaluations made by 20 young adults. Statistical analysis revealed a larger feedback related negativity (FRN effect between loss and gain following immediate outcomes than following future outcomes. In addition, delay impacted FRN only in gain conditions, with delayed winning eliciting a more negative FRN than immediatewinning. These results suggest that temporal discounting and sign effect could be encoded in the FRN in the early stage of outcome evaluation.

  2. Modulating resonance behaviors by noise recycling in bistable systems with time delay

    International Nuclear Information System (INIS)

    In this paper, the impact of noise recycling on resonance behaviors is studied theoretically and numerically in a prototypical bistable system with delayed feedback. According to the interior cooperating and interacting activity of noise recycling, a theory has been proposed by reducing the non-Markovian problem into a two-state model, wherein both the master equation and the transition rates depend on not only the current state but also the earlier two states due to the recycling lag and the feedback delay. By virtue of this theory, the formulae of the power spectrum density and the linear response function have been found analytically. And the theoretical results are well verified by numerical simulations. It has been demonstrated that both the recycling lag and the feedback delay play a crucial role in the resonance behaviors. In addition, the results also suggest an alternative scheme to modulate or control the coherence or stochastic resonance in bistable systems with time delay

  3. Effect of Boron on Delayed Fracture Resistance of Medium-Carbon High Strength Spring Steel

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The delayed fracture behavior of medium-carbon high strength spring steel containing different amounts of boron (0. 000 5%, 0. 001 6%) was studied using sustained load delayed fracture test. The results show that delayed fracture resistance of boron containing steels is higher than that of conventional steel 60Si2MnA at the same strength level and it increases with the increase of boron content from 0. 000 5 % to 0. 001 6 %. The delayed fracture mode is mainly intergranular in the boron containing steels tempered at 350 ℃, which indicates that the addition of boron does not change the fracture character. However, the increase of boron content enlarges the size of the crack initiation area. Further study of phase analysis indicates that most boron is in solid solution, and only a very small quantity of boron is in the M3 (C, B) phase.

  4. Modulating resonance behaviors by noise recycling in bistable systems with time delay

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Zhongkui, E-mail: sunzk2008@gmail.com; Xu, Wei [Department of Applied Mathematics, Northwestern Polytechnical University, Xi' an 710072 (China); Yang, Xiaoli [College of Mathematics and Information Science, Shaan' xi Normal University, Xi' an 710062 (China); Xiao, Yuzhu [Department of Mathematics and Information Science, Chang' an University, Xi' an 710086 (China)

    2014-06-01

    In this paper, the impact of noise recycling on resonance behaviors is studied theoretically and numerically in a prototypical bistable system with delayed feedback. According to the interior cooperating and interacting activity of noise recycling, a theory has been proposed by reducing the non-Markovian problem into a two-state model, wherein both the master equation and the transition rates depend on not only the current state but also the earlier two states due to the recycling lag and the feedback delay. By virtue of this theory, the formulae of the power spectrum density and the linear response function have been found analytically. And the theoretical results are well verified by numerical simulations. It has been demonstrated that both the recycling lag and the feedback delay play a crucial role in the resonance behaviors. In addition, the results also suggest an alternative scheme to modulate or control the coherence or stochastic resonance in bistable systems with time delay.

  5. Pubertal growth of the medial amygdala delayed by short photoperiods in the Siberian hamster, Phodopus sungorus.

    Science.gov (United States)

    Cooke, Bradley M; Jordan, Cynthia L; Breedlove, S Marc

    2007-09-01

    We investigated whether puberty influences the morphology of the medial nucleus of the amygdala (MeA) by comparing Siberian hamsters (Phodopus sungorus) that had been raised from birth in either long day (LD; 16:8 h light:dark) or short day (SD; 8:16) photoperiods. Hamsters were sacrificed at 42-49 days of age, at which point all LD hamsters were reproductively mature, as evidenced by adult-like testes weights (mean: 657 mg). In contrast, the testes weights of the SD hamsters were low (mean: 31 mg), indicating that the SD photoperiod had delayed puberty. The regional volume and mean soma size of the four MeA subnuclei was estimated bilaterally by stereological procedures. In the posterior dorsal and ventral MeA subnuclei, regional volume was 22-25% larger, and mean soma size 18% larger, in LD males than SD males. Unbiased cell counts in the posterior dorsal MeA showed that LD and SD hamsters have equivalent neuron numbers. In the anterior MeA subnuclei, regional volumes and soma sizes from LD and SD hamsters were equivalent. Additionally, the regional volume of the posteroventral subnucleus was larger in the right hemisphere than the left, but this laterality did not respond to photoperiod manipulation. These results suggest that the extant neurons within the posterior MeA, a steroid-sensitive nucleus implicated in socio-sexual behavior, grow in response to the elevated levels of circulating androgen accompanying puberty, and that photoperiodic regulation of puberty affects morphological maturation of this nucleus.

  6. Data Assimilation by delay-coordinate nudging

    Science.gov (United States)

    Pazo, Diego; Lopez, Juan Manuel; Carrassi, Alberto

    2016-04-01

    A new nudging method for data assimilation, delay-coordinate nudging, is presented. Delay-coordinate nudging makes explicit use of present and past observations in the formulation of the forcing driving the model evolution at each time-step. Numerical experiments with a low order chaotic system show that the new method systematically outperforms standard nudging in different model and observational scenarios, also when using an un-optimized formulation of the delay-nudging coefficients. A connection between the optimal delay and the dominant Lyapunov exponent of the dynamics is found based on heuristic arguments and is confirmed by the numerical results, providing a guideline for the practical implementation of the algorithm. Delay-coordinate nudging preserves the easiness of implementation, the intuitive functioning and the reduced computational cost of the standard nudging, making it a potential alternative especially in the field of seasonal-to-decadal predictions with large Earth system models that limit the use of more sophisticated data assimilation procedures.

  7. Delayed Station Blackout Event and Nuclear Safety

    Directory of Open Access Journals (Sweden)

    Andrija Volkanovski

    2015-01-01

    Full Text Available The loss of off-site power (LOOP event occurs when all electrical power to the nuclear power plant from the power grid is lost. Complete failure of both off-site and on-site alternating current (AC power sources is referred to as a station blackout (SBO. Combined LOOP and SBO events are analyzed in this paper. The analysis is done for different time delays between the LOOP and SBO events. Deterministic safety analysis is utilized for the assessment of the plant parameters for different time delays of the SBO event. Obtained plant parameters are used for the assessment of the probabilities of the functional events in the SBO event tree. The results show that the time delay of the SBO after the LOOP leads to a decrease of the core damage frequency (CDF from the SBO event tree. The reduction of the CDF depends on the time delay of the SBO after the LOOP event. The results show the importance of the safety systems to operate after the plant shutdown when the decay heat is large. Small changes of the basic events importance measures are identified with the introduction of the delay of the SBO event.

  8. Computing using delayed feedback systems: towards photonics

    Science.gov (United States)

    Appeltant, L.; Soriano, M. C.; Van der Sande, G.; Danckaert, J.; Massar, S.; Dambre, J.; Schrauwen, B.; Mirasso, C. R.; Fischer, I.

    2012-06-01

    Reservoir computing has recently been introduced as a new paradigm in the eld of machine learning. It is based on the dynamical properties of a network of randomly connected nodes or neurons and shows to be very promising to solve complex classication problems in a computationally ecient way. The key idea is that an input generates nonlinearly transient behavior rendering transient reservoir states suitable for linear classication. Our goal is to study up to which extent systems with delay, and especially photonic systems, can be used as reservoirs. Recently an new architecture has been proposed1 , based on a single nonlinear node with delayed feedback. An electronic1 and an opto-electronic implementation2, 3 have been demonstrated and both have proven to be very successful in terms of performance. This simple conguration, which replaces an entire network of randomly connected nonlinear nodes with one single hardware node and a delay line, is signicantly easier to implement experimentally. It is no longer necessary to construct an entire network of hundreds or even thousands of circuits, each one representing a node. With this approach one node and a delay line suce to construct a computational unit. In this manuscript, we present a further investigation of the properties of delayed feedback congurations used as a reservoir. Instead of quantifying the performance as an error obtained for a certain benchmark, we now investigate a task-independent property, the linear memory of the system.

  9. Performansi Parameter Delay Pada Aplikasi Monitoring DIAMon

    Directory of Open Access Journals (Sweden)

    Kurnia Ageng Pratama

    2013-03-01

    Full Text Available Kemampuan seorang administrator jaringan untuk mengawasi jaringan sangat penting agar jaringan tersebut dapat beroperasi dengan baik. Maka diperlukan aplikasi monitoring jaringan yang dapat memberikan informasi yang sedang terjadi pada jaringan tersebut, sehingga memudahkan administrator jaringan untuk mengatur dan bertindak agar jaringan tersebut memiliki kinerja yang baik. Salah satu parameter untuk menganalisa kondisi sebuah jaringan adalah delay. Metodologi pada tugas akhir ini dengan perancangan sistem terintegrasi monitoring delay dengan web aplikasi, pengujian monitoring delay dengan ping, pengambilan dan perhitungan statistik dari database MySQL, pengujian aplikasi monitoring DIAMon yang sudah terintegrasi dan penarikan kesimpulan dari pengujian dan hasil analisa data. Tugas akhir ini dibuat sebuah aplikasi monitoring DIAMon yang mampu mengukur delay dan ditampilkan dalam suatu dashboard yang komunikatif sehingga dapat membantu adminstrator jaringan bekerja. Dan didapatkan rata-rata selisih terbaik antara aplikasi monitoring DIAMon dengan PRTG yaitu 30,19853% dan terburuk yaitu 46,73768%. Sedangkan rata-rata selisih terbaik antara aplikasi monitoring DIAMon dengan perhitungan delay yaitu 57,79807% dan terburuk yaitu 91,69501%.  

  10. The use of delay in multitrack production

    Science.gov (United States)

    Case, Alexander U.

    2003-04-01

    Delay, inevitable whenever sound propagates through space, is too often the bane of the acoustician's practice. An audible echo generally relegates a music performance hall-no matter how beautiful it otherwise might sound-to the lowest status. Multitrack music production on the other hand, with its aggressive use of overdubbing, editing, and signal processing, is not bound by those rules of time and space which determine the sound of a hall. In the recording studio, where music is synthesized for playback over loudspeakers, the delay is employed as a powerful, multipurpose tool. It is not avoided. It is in fact embraced. Echoes are used on purpose, strategically, to enhance the loudspeaker listening experience. Moreover, the humble delay is the basis for many nonecho effects. Flanging, chorus, and pitch shifting are delay-based effects regularly used in audio engineering practice. This paper discusses some of the more common delay-based effects, reviewing their technical structure, the psychoacoustic motivation behind them, and the musical value they create.

  11. Recent advances of harmonic delay models for the neutral atmosphere (Invited)

    Science.gov (United States)

    Schindelegger, M.; Böhm, J.; Pain, G.

    2013-12-01

    The path delay caused by the neutral atmosphere is one of the main factors limiting the accuracy of positioning products from the analysis of space geodetic observations, like those from GNSS (Global Navigation Satellite Systems). For a precise account of this effect, the slant path delays are typically separated into a hydrostatic part and a wet part with each of them being the product of the zenith delay and a mapping function. If available, the analyst is advised to determine the zenith hydrostatic delay from pressure values recorded at the site, to derive the mapping functions from operational analysis fields of numerical weather models, and to estimate the zenith wet delay within the least-squares adjustment. If neither local pressure values nor operational mapping functions can be accessed, it is recommended to use so-called blind models which are based on harmonic functions and do not need any parameters other than approximate position and date. We outline the recent advances made in this field of empirical models for tropospheric slant delays by reference to GPT2, an improved version of the Global Pressure and Temperature (GPT) model and the Global Mapping Functions (GMF). Characterized by an increased horizontal resolution of 5 degrees, a temporal variability down to semi-annual periodicities, and an extended set of meteorological parameters, the model's excellent usability for GNSS applications is demonstrated by validation against in-situ pressure and temperature observations as well as ray-traced delays. In addition, real time positioning and navigation applications profit from another, currently developed augmentation of GPT2 in terms of accurate a priori estimates for zenith wet delays. We discuss the subtleties of this extension and assess its performance by comparing to zenith total delays from GNSS solutions in 2011-2012.

  12. The diffusive Lotka-Volterra predator-prey system with delay.

    Science.gov (United States)

    Al Noufaey, K S; Marchant, T R; Edwards, M P

    2015-12-01

    Semi-analytical solutions for the diffusive Lotka-Volterra predator-prey system with delay are considered in one and two-dimensional domains. The Galerkin method is applied, which approximates the spatial structure of both the predator and prey populations. This approach is used to obtain a lower-order, ordinary differential delay equation model for the system of governing delay partial differential equations. Steady-state and transient solutions and the region of parameter space, in which Hopf bifurcations occur, are all found. In some cases simple linear expressions are found as approximations, to describe steady-state solutions and the Hopf parameter regions. An asymptotic analysis for the periodic solution near the Hopf bifurcation point is performed for the one-dimensional domain. An excellent agreement is shown in comparisons between semi-analytical and numerical solutions of the governing equations. PMID:26471317

  13. The diffusive Lotka-Volterra predator-prey system with delay.

    Science.gov (United States)

    Al Noufaey, K S; Marchant, T R; Edwards, M P

    2015-12-01

    Semi-analytical solutions for the diffusive Lotka-Volterra predator-prey system with delay are considered in one and two-dimensional domains. The Galerkin method is applied, which approximates the spatial structure of both the predator and prey populations. This approach is used to obtain a lower-order, ordinary differential delay equation model for the system of governing delay partial differential equations. Steady-state and transient solutions and the region of parameter space, in which Hopf bifurcations occur, are all found. In some cases simple linear expressions are found as approximations, to describe steady-state solutions and the Hopf parameter regions. An asymptotic analysis for the periodic solution near the Hopf bifurcation point is performed for the one-dimensional domain. An excellent agreement is shown in comparisons between semi-analytical and numerical solutions of the governing equations.

  14. Effect of Delay on Children's Delay-Execute Prospective Memory Performance

    Science.gov (United States)

    Rendell, Peter G.; Vella, Melissa J.; Kliegel, Matthias; Terrett, Gill

    2009-01-01

    To date, little work has been done investigating prospective memory in children, particularly using a delay-execute paradigm. Two experiments were conducted to investigate this issue with children aged 5-11 years. While playing a computer driving game, children's ability to carry out a delayed intention either immediately a target cue appeared or…

  15. Robust delay-dependent feedforward control of neutral time-delay systems via dynamic IQCs

    Science.gov (United States)

    Ucun, L.; Küçükdemiral, I. B.

    2014-05-01

    This paper studies the design problem of delay-dependent ? based robust and optimal feedforward controller design for a class of time-delay control systems having state, control and neutral type delays which are subject to norm-bounded uncertainties and ? type measurable or observable disturbance signals. Two independent loops which include state-feedback and dynamic feedforward controller form the basis of the proposed control scheme in this study. State-feedback controller is generally used in stabilisation of the nominal delay-free system, whereas the feedforward controller is used for improving disturbance attenuation performance of the overall system. In order to obtain less conservative results, the delay and parametric uncertainty effects are treated in operator view point and represented by frequency-dependent (dynamic) integral quadratic constraints (IQCs). Moreover, sufficient delay-dependent criterion is developed in terms of linear matrix inequalities (LMIs) such that the time-delay system having parametric uncertainties is guaranteed to be asymptotically stable with minimum achievable disturbance attenuation level. Plenty of numerical examples are provided at the end, in order to illustrate the efficiency of the proposed technique. The achieved results on minimum achievable disturbance attenuation level and maximum allowable delay bounds are exhibited to be less conservative in comparison to those of controllers having only feedback loop.

  16. A Comparison of Motor Delays in Young Children: Autism Spectrum Disorder, Developmental Delay, and Developmental Concerns

    Science.gov (United States)

    Provost, Beth; Lopez, Brian R.; Heimerl, Sandra

    2007-01-01

    This study assessed motor delay in young children 21-41 months of age with autism spectrum disorder (ASD), and compared motor scores in children with ASD to those of children without ASD. Fifty-six children (42 boys, 14 girls) were in three groups: children with ASD, children with developmental delay (DD), and children with developmental concerns…

  17. A DELAY-DEPENDENT STABILITY CRITERION FOR NONLINEAR STOCHASTIC DELAY-INTEGRO-DIFFERENTIAL EQUATIONS

    Institute of Scientific and Technical Information of China (English)

    Niu Yuanling; Zhang Chengjian; Duan Jinqiao

    2011-01-01

    A type of complex systems under both random influence and memory effects is considered.The systems are modeled by a class of nonlinear stochastic delay-integrodifferential equations.A delay-dependent stability criterion for such equations is derived under the condition that the time lags are small enough.Numerical simulations are presented to illustrate the theoretical result.

  18. Delay-Dependent Exponential Stability Criterion for BAM Neural Networks with Time-Varying Delays

    Institute of Scientific and Technical Information of China (English)

    Wei-Wei Su; Yi-Ming Chen

    2008-01-01

    By employing the Lyapunov stability theory and linear matrix inequality (LMI) technique, delay dependent stability criterion is derived to ensure the exponential stability of bi-directional associative memory (BAM) neural networks with time-varying delays. The proposed condition can be checked easily by LMI control toolbox in Matlab. A numerical example is given to demonstrate the effectiveness of our results.

  19. Putative sugarcane FT/TFL1 genes delay flowering time and alter reproductive architecture in Arabidopsis

    Directory of Open Access Journals (Sweden)

    Carla P. Coelho

    2014-05-01

    Full Text Available Agriculturally important grasses such as rice, maize and sugarcane are evolutionarily distant from Arabidopsis, yet some components of the floral induction process are highly conserved. Flowering in sugarcane is an important factor that negatively affects cane yield and reduces sugar/ethanol production from this important perennial bioenergy crop. Comparative studies have facilitated the identification and characterization of putative orthologs of key flowering time genes in sugarcane, a complex polyploid plant whose genome has yet to be sequenced completely. Using this approach we identified phosphatidylethanolamine-binding protein (PEBP gene family members in sugarcane that are similar to the archetypical FT and TFL1 genes of Arabidopsis that play an essential role in controlling the transition from vegetative to reproductive growth. Expression analysis of ScTFL1, which falls into the TFL1-clade of floral repressors, showed transcripts in developing leaves surrounding the shoot apex but not at the apex itself. ScFT1 was detected in immature leaves and apical regions of vegetatively growing plants and, after the floral transition, expression also occurred in mature leaves. Ectopic over-expression of ScTFL1 in Arabidopsis caused delayed flowering in Arabidopsis, as might be expected for a gene related to TFL1. In addition, lines with the latest flowering phenotype exhibited aerial rosette formation. Unexpectedly, over-expression of ScFT1, which has greatest similarity to the florigen-encoding FT, also caused a delay in flowering. This preliminary analysis of divergent sugarcane FT and TFL1 gene family members from Saccharum spp. suggests that their expression patterns and roles in the floral transition has diverged from the predicted role of similar PEBP family members.

  20. Putative sugarcane FT/TFL1 genes delay flowering time and alter reproductive architecture in Arabidopsis

    Science.gov (United States)

    Coelho, Carla P.; Minow, Mark A. A.; Chalfun-Júnior, Antonio; Colasanti, Joseph

    2014-01-01

    Agriculturally important grasses such as rice, maize, and sugarcane are evolutionarily distant from Arabidopsis, yet some components of the floral induction process are highly conserved. Flowering in sugarcane is an important factor that negatively affects cane yield and reduces sugar/ethanol production from this important perennial bioenergy crop. Comparative studies have facilitated the identification and characterization of putative orthologs of key flowering time genes in sugarcane, a complex polyploid plant whose genome has yet to be sequenced completely. Using this approach we identified phosphatidylethanolamine-binding protein (PEBP) gene family members in sugarcane that are similar to the archetypical FT and TFL1 genes of Arabidopsis that play an essential role in controlling the transition from vegetative to reproductive growth. Expression analysis of ScTFL1, which falls into the TFL1-clade of floral repressors, showed transcripts in developing leaves surrounding the shoot apex but not at the apex itself. ScFT1 was detected in immature leaves and apical regions of vegetatively growing plants and, after the floral transition, expression also occurred in mature leaves. Ectopic over-expression of ScTFL1 in Arabidopsis caused delayed flowering in Arabidopsis, as might be expected for a gene related to TFL1. In addition, lines with the latest flowering phenotype exhibited aerial rosette formation. Unexpectedly, over-expression of ScFT1, which has greatest similarity to the florigen-encoding FT, also caused a delay in flowering. This preliminary analysis of divergent sugarcane FT and TFL1 gene family members from Saccharum spp. suggests that their expression patterns and roles in the floral transition has diverged from the predicted role of similar PEBP family members. PMID:24904616

  1. A rare association between Rathke's cyst and hypophysitis in a patient with delayed sex development and growth failure.

    Science.gov (United States)

    Takahashi, Daisuke; Kobayashi, Hiroyuki; Kubota, Kanako; Suzuki, Yasuto; Nakamura, Akie; Ishizu, Katsura; Nakanishi, Masanori; Nagashima, Tetsuro; Tajima, Toshihiro

    2013-01-01

    We report an 18-year-old Japanese male with a lack of secondary sex characterization and growth failure caused by a rare association between Rathke's cyst and hypophysitis. He was referred to us because of delayed secondary sex characterization. Endocrinological examination showed panhypopituitarism, and the replacement of hydrocortisone, levothyroxine, and desmopressin acetate (DDAVP) was initiated. Brain magnetic resonance imaging (MRI) showed a suprasellar region and a swollen pituitary stalk. The mass was partially resected using the transsphenoidal approach. The pathological diagnosis was hypophysitis and Rathke's cyst. Follow-up MRI performed 1 year after surgery showed that the size of sellar region had not changed. After surgery, in addition to pre-operative hormonal replacement, growth hormone and testosterone were initiated. Two years later, the size of sellar region remains unchanged. In conclusion, while an association between Rathke's cyst and hypophysitis is rare, we suggest that this condition should be included in differential diagnosis of the sellar region, even in adolescents. PMID:23729539

  2. Informed Network Coding for Minimum Decoding Delay

    CERN Document Server

    Costa, Rui A; Widmer, Joerg; Barros, Joao

    2008-01-01

    Network coding is a highly efficient data dissemination mechanism for wireless networks. Since network coded information can only be recovered after delivering a sufficient number of coded packets, the resulting decoding delay can become problematic for delay-sensitive applications such as real-time media streaming. Motivated by this observation, we consider several algorithms that minimize the decoding delay and analyze their performance by means of simulation. The algorithms differ both in the required information about the state of the neighbors' buffers and in the way this knowledge is used to decide which packets to combine through coding operations. Our results show that a greedy algorithm, whose encodings maximize the number of nodes at which a coded packet is immediately decodable significantly outperforms existing network coding protocols.

  3. Delay estimation for CMOS functional cells

    DEFF Research Database (Denmark)

    Madsen, Jan

    1991-01-01

    Presents a new RC tree network model for delay estimation of CMOS functional cells. The model is able to reflect topological changes within a cell, which is of particular interest when doing performance driven layout synthesis. Further, a set of algorithms to perform worst case analysis on arbitr...... arbitrary CMOS functional cells using the proposed delay model, is presented. Both model and algorithms have been implemented as a part of a cell compiler (CELLO) working in an experimental silicon compiler environment.......Presents a new RC tree network model for delay estimation of CMOS functional cells. The model is able to reflect topological changes within a cell, which is of particular interest when doing performance driven layout synthesis. Further, a set of algorithms to perform worst case analysis on...

  4. Delayed switching applied to memristor neural networks

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Frank Z.; Yang Xiao; Lim Guan [Future Computing Group, School of Computing, University of Kent, Canterbury (United Kingdom); Helian Na [School of Computer Science, University of Hertfordshire, Hatfield (United Kingdom); Wu Sining [Xyratex, Havant (United Kingdom); Guo Yike [Department of Computing, Imperial College, London (United Kingdom); Rashid, Md Mamunur [CERN, Geneva (Switzerland)

    2012-04-01

    Magnetic flux and electric charge are linked in a memristor. We reported recently that a memristor has a peculiar effect in which the switching takes place with a time delay because a memristor possesses a certain inertia. This effect was named the ''delayed switching effect.'' In this work, we elaborate on the importance of delayed switching in a brain-like computer using memristor neural networks. The effect is used to control the switching of a memristor synapse between two neurons that fire together (the Hebbian rule). A theoretical formula is found, and the design is verified by a simulation. We have also built an experimental setup consisting of electronic memristive synapses and electronic neurons.

  5. Time delay measurement in the frequency domain

    Energy Technology Data Exchange (ETDEWEB)

    Durbin, Stephen M., E-mail: durbin@purdue.edu; Liu, Shih-Chieh [Purdue University, West Lafayette, IN 47907 (United States); Dufresne, Eric M.; Li, Yuelin; Wen, Haidan [Argonne National Laboratory, Argonne, IL 60439 (United States)

    2015-08-06

    A simple frequency domain technique for determining the time delay between laser pump and X-ray probe pulses achieves 1 ps resolution even for ∼100 ps synchrotron pulses, permitting improved pump–probe characterization of ultrafast processes. Pump–probe studies at synchrotrons using X-ray and laser pulses require accurate determination of the time delay between pulses. This becomes especially important when observing ultrafast responses with lifetimes approaching or even less than the X-ray pulse duration (∼100 ps). The standard approach of inspecting the time response of a detector sensitive to both types of pulses can have limitations due to dissimilar pulse profiles and other experimental factors. Here, a simple alternative is presented, where the frequency response of the detector is monitored versus time delay. Measurements readily demonstrate a time resolution of ∼1 ps. Improved precision is possible by simply extending the data acquisition time.

  6. Delayed reconstruction of a quadriceps tendon.

    Science.gov (United States)

    Pocock, C A J; Trikha, S P; Bell, J S P

    2008-01-01

    Rupture of the quadriceps tendon is an uncommon injury and rapid diagnosis is important because delay in surgical repair generally is believed to adversely affect outcome. One study of 20 patients suggests repair should be done during the first 48 to 72 hours postinjury to achieve a successful outcome and late repair led to unsatisfactory recovery. Cases of delayed tendon repair have been reported, the longest to our knowledge being 11 months before surgical intervention. We present a case of successful outcome of a quadriceps tendon rupture reconstructed at least 8 years after occurrence and a review of the literature of delayed reconstructions. We show that successful restoration of extensor mechanism function can be achieved several years after tendon rupture.

  7. Time-delayed autosynchronous swarm control

    Science.gov (United States)

    Biggs, James D.; Bennet, Derek J.; Dadzie, S. Kokou

    2012-01-01

    In this paper a general Morse potential model of self-propelling particles is considered in the presence of a time-delayed term and a spring potential. It is shown that the emergent swarm behavior is dependent on the delay term and weights of the time-delayed function, which can be set to induce a stationary swarm, a rotating swarm with uniform translation, and a rotating swarm with a stationary center of mass. An analysis of the mean field equations shows that without a spring potential the motion of the center of mass is determined explicitly by a multivalued function. For a nonzero spring potential the swarm converges to a vortex formation about a stationary center of mass, except at discrete bifurcation points where the center of mass will periodically trace an ellipse. The analytical results defining the behavior of the center of mass are shown to correspond with the numerical swarm simulations.

  8. Time delays in correlated photoemission processes

    Science.gov (United States)

    Pazourek, R.; Nagele, S.; Burgdörfer, J.

    2015-09-01

    We theoretically study time-resolved two-photon double ionization (TPDI) of helium as probed by attosecond streaking. We review recent advances in the understanding of the photoelectric effect in the time domain and discuss the differences between one- and two-photon ionization, as well as one- and two-electron emission. We perform exact ab-initio simulations for attosecond streaking experiments in the sequential TPDI regime and compare the results to the two-electron Eisenbud-Wigner-Smith delay for the process. Our calculations directly show that the timing of the emission process sensitively depends on the energy sharing between the two outgoing electrons. In particular, we identify Fano-like interferences in the relative time delay of the two emitted electrons when the sequential ionization channel occurs via intermediate excited ionic (shake-up) states. Furthermore, we find that the photoemission time delays are only weakly dependent on the relative emission angle of the ejected electrons.

  9. Delay-dependent stability and stabilization criteria of networked control systems with multiple time-delays

    Institute of Scientific and Technical Information of China (English)

    Huaicheng YAN; Xinhan HUANG; Min WANG

    2006-01-01

    This paper deals with the problem of delay-dependent stability and stabilization for networked control systems(NCSs)with multiple time-delays. In view of multi-input and multi-output(MIMO) NCSs with many independent sensors and actuators, a continuous time model with distributed time-delays is proposed. Utilizing the Lyapunov stability theory combined with linear matrix inequalities(LMIs) techniques, some new delay-dependent stability criteria for NCSs in terms of generalized Lyapunov matrix equation and LMIs are derived. Stabilizing controller via state feedback is formulated by solving a set of LMIs. Compared with the reported methods, the proposed methods give a less conservative delay bound and more general results. Numerical example and simulation show that the methods are less conservative and more effective.

  10. Delay-dependent stability and stabilisation of continuous 2D delayed systems with saturating control

    Science.gov (United States)

    Hmamed, Abdelaziz; Kririm, Said; Benzaouia, Abdellah; Tadeo, Fernando

    2016-09-01

    This paper deals with the stabilisation problem of continuous two-dimensional (2D) delayed systems, in the presence of saturations on the control signals. For this, a new delay decomposition approach is proposed to deal with the stability and stabilisation issues. The idea is that the range of variation of each delay is divided into segments, and a specific Lyapunov- Krasovskii functional is used that contains different weight matrices in each segment. Then, based on this approach, new delay-dependent stability and stabilisation criteria for continuous 2D delayed systems are derived. These criteria are less conservative and include some existing results as special cases. Some numerical examples are provided to show that a significant improvement is achieved using the proposed approach.

  11. Linear delay-differential systems with commensurate delays an algebraic approach

    CERN Document Server

    Gluesing-Luerssen, Heide

    2002-01-01

    The book deals with linear time-invariant delay-differential equations with commensurated point delays in a control-theoretic context. The aim is to show that with a suitable algebraic setting a behavioral theory for dynamical systems described by such equations can be developed. The central object is an operator algebra which turns out to be an elementary divisor domain and thus provides the main tool for investigating the corresponding matrix equations. The book also reports the results obtained so far for delay-differential systems with noncommensurate delays. Moreover, whenever possible it points out similarities and differences to the behavioral theory of multidimensional systems, which is based on a great deal of algebraic structure itself. The presentation is introductory and self-contained. It should also be accessible to readers with no background in delay-differential equations or behavioral systems theory. The text should interest researchers and graduate students.

  12. Classic conditioning in aged rabbits: delay, trace, and long-delay conditioning.

    Science.gov (United States)

    Solomon, P R; Groccia-Ellison, M E

    1996-06-01

    Young (0.5 years) and aged (2+, 3+, and 4+ years) rabbits underwent acquisition of the classically conditioned nictitating membrane response in a delay (500-ms conditioned stimulus [CS], 400-ms interstimulus interval [ISI]), long-delay (1,000-ms CS, 900-ms ISI), or trace (500-ms CS, 400-ms stimulus-free period) paradigm. Collapsing across age groups, there is a general tendency for animals to acquire trace conditioning more slowly than delay conditioning. Collapsing across conditioning paradigms, there is a general tendency for aged animals to acquire more slowly than younger animals. Of greater significance, however, are the age differences in the different conditioning paradigms. In the delay and long-delay paradigms, significant conditioning deficits first appeared in the 4(+)-year-old group. In the trace conditioning paradigm, significant conditioning deficits became apparent in the 2(+)-year-old animals.

  13. Asymptotic Hyperstability of Dynamic Systems with Point Delays

    Directory of Open Access Journals (Sweden)

    M. De la Sen

    2005-01-01

    Full Text Available It is proved that a linear time-invariant system with internal point delays is asymptotically hyperstable independent of the delays if an associate delay-free system is asymptotically hyperstable and the delayed dynamics are sufficiently small.

  14. Delayed-onset akathisia due to amisulpride

    Directory of Open Access Journals (Sweden)

    Murad Atmaca

    2011-01-01

    Full Text Available Despite the fact that second-generation antipsychotics have a lower potential to cause extrapyramidal side-effects, including akathisia, their incidence is not negligible. Recent work suggests that tardive akathisia may have pharmacological differences from acute akathisia. In the present study, we have evaluated the nature of delayed-onset akathisia in patients on amisülpride monotherapy. Overall, we screened 56 patients on amisulpride treatment for 2 months at a stabilized amisulpride dose. However, 18 patients with diagnostic and statistical manual of mental disorders-IV (DSM-IV presented with acute or delayed-onset akathisia, and all of them also met the entry criteria. The patients were evaluated at baseline and at the time when akathisia presented clinically, with respect to the Positive and Negative Syndrome Scale and Barnes Akathisia Scale (BAS. Using the primary categorical criterion of akathisia (≥2 points of the BAS global scale, 12 (21.4% of the 56 patients experienced delayed-onset akathisia, and six (10.7% showed acute akathisia. The mean time for onset of acute or delayed-onset akathisia was 5.8 ± 2.1 and 39.4 ± 11.3 days, respectively. The mean BAS scores at baseline and after the period of 2 months were 1.3 ± 0.6 and 3.9 ± 2.4, respectively (P < 0.001. Our results revealed that amisulpride could considerably lead to delayed-onset akathisia. However, studies comprising larger samples receiving different antipsychotics, and more comprehensive assessment, will help to ascertain the role of amisulpride in delayed-onset akathisia.

  15. The Strong Lensing Time Delay Challenge (2014)

    Science.gov (United States)

    Liao, Kai; Dobler, G.; Fassnacht, C. D.; Treu, T.; Marshall, P. J.; Rumbaugh, N.; Linder, E.; Hojjati, A.

    2014-01-01

    Time delays between multiple images in strong lensing systems are a powerful probe of cosmology. At the moment the application of this technique is limited by the number of lensed quasars with measured time delays. However, the number of such systems is expected to increase dramatically in the next few years. Hundred such systems are expected within this decade, while the Large Synoptic Survey Telescope (LSST) is expected to deliver of order 1000 time delays in the 2020 decade. In order to exploit this bounty of lenses we needed to make sure the time delay determination algorithms have sufficiently high precision and accuracy. As a first step to test current algorithms and identify potential areas for improvement we have started a "Time Delay Challenge" (TDC). An "evil" team has created realistic simulated light curves, to be analyzed blindly by "good" teams. The challenge is open to all interested parties. The initial challenge consists of two steps (TDC0 and TDC1). TDC0 consists of a small number of datasets to be used as a training template. The non-mandatory deadline is December 1 2013. The "good" teams that complete TDC0 will be given access to TDC1. TDC1 consists of thousands of lightcurves, a number sufficient to test precision and accuracy at the subpercent level, necessary for time-delay cosmography. The deadline for responding to TDC1 is July 1 2014. Submissions will be analyzed and compared in terms of predefined metrics to establish the goodness-of-fit, efficiency, precision and accuracy of current algorithms. This poster describes the challenge in detail and gives instructions for participation.

  16. Delayed recompression for decompression sickness: retrospective analysis.

    Directory of Open Access Journals (Sweden)

    Amir Hadanny

    Full Text Available Most cases of decompression sickness (DCS occur soon after surfacing, with 98% within 24 hours. Recompression using hyperbaric chamber should be administrated as soon as feasible in order to decrease bubble size and avoid further tissue injury. Unfortunately, there may be a significant time delay from surfacing to recompression. The time beyond which hyperbaric treatment is non effective is unclear. The aims of the study were first to evaluate the effect of delayed hyperbaric treatment, initiated more than 48 h after surfacing for DCS and second, to evaluate the different treatment protocols.From January 2000 to February 2014, 76 divers had delayed hyperbaric treatment (≥48 h for DCS in the Sagol center for Hyperbaric medicine and Research, Assaf-Harofeh Medical Center, Israel. Data were collected from their medical records and compared to data of 128 patients treated earlier than 48 h after surfacing at the same hyperbaric institute.There was no significant difference, as to any of the baseline characteristics, between the delayed and early treatment groups. With respect to treatment results, at the delayed treatment divers, complete recovery was achieved in 76% of the divers, partial recovery in 17.1% and no improvement in 6.6%. Similar results were achieved when treatment started early, where 78% of the divers had complete recovery, 15.6% partial recovery and 6.2% no recovery. Delayed hyperbaric treatment using US Navy Table 6 protocol trended toward a better clinical outcome yet not statistically significant (OR=2.786, CI95%[0.896-8.66], p=0.07 compared to standard hyperbaric oxygen therapy of 90 minutes at 2 ATA, irrespective of the symptoms severity at presentation.Late recompression for DCS, 48 hours or more after surfacing, has clinical value and when applied can achieve complete recovery in 76% of the divers. It seems that the preferred hyperbaric treatment protocol should be based on US Navy Table 6.

  17. On the time delay between ultrarelativistic particles

    CERN Document Server

    Fleury, Pierre

    2016-01-01

    The time delay between the receptions of ultrarelativistic particles emitted simultaneously is an observable for both fundamental physics and cosmology. The expression of the delay when the particles travel through an arbitrary spacetime has been derived recently in arXiv:1512.08489, using a particular coordinate system and self-consistent assumptions. In this article I show that this formula enjoys a simple physical interpretation: the relative velocity between two ultrarelativistic particles is constant. This result reveals an interesting kinematical property of general relativity, namely that the tidal forces experienced by ultrarelativistic particles in the direction of their motion are much smaller than those experienced orthogonally to their motion.

  18. Delay generation methods with reduced memory requirements

    DEFF Research Database (Denmark)

    Tomov, Borislav Gueorguiev; Jensen, Jørgen Arendt

    2003-01-01

    Modern diagnostic ultrasound beamformers require delay information for each sample along the image lines. In order to avoid storing large amounts of focusing data, delay generation techniques have to be used. In connection with developing a compact beamformer architecture, recursive algorithms were...... investigated. These included an original design and a technique developed by another research group. A piecewise-linear approximation approach was also investigated. Two imaging setups were targeted - conventional beamforming with a sampling frequency of 40 MHz and subsample precision of 2 bits...

  19. Causal Analysis of Railway Running Delays

    DEFF Research Database (Denmark)

    Cerreto, Fabrizio; Nielsen, Otto Anker; Harrod, Steven;

    Operating delays and network propagation are inherent characteristics of railway operations. These are traditionally reduced by provision of time supplements or “slack” in railway timetables and operating plans. Supplement allocation policies must trade off reliability in the service commitments...... Denmark (the Danish infrastructure manager). The statistical analysis of the data identifies the minimum running times and the scheduled running time supplements and investigates the evolution of train delays along given train paths. An improved allocation of time supplements would result in smaller...

  20. Global Synchronization of General Delayed Dynamical Networks

    Institute of Scientific and Technical Information of China (English)

    LI Zhi

    2007-01-01

    Global synchronization of general delayed dynamical networks with linear coupling are investigated. A sufficient condition for the global synchronization is obtained by using the linear matrix inequality and introducing a reference state. This condition is simply given based on the maximum nonzero eigenvalue of the network coupling matrix. Moreover, we show how to construct the coupling matrix to guarantee global synchronization of network,which is very convenient to use. A two-dimension system with delay as a dynamical node in network with global coupling is finally presented to verify the theoretical results of the proposed global synchronization scheme.

  1. Delay in diagnosis of congenital anal stenosis

    Directory of Open Access Journals (Sweden)

    Elroy P. Weledji

    2016-03-01

    Full Text Available Although a minor anorectal malformation the delay in diagnosis and treatment of anal stenosis may result in significant early or late complications. Early inspection of the perineum in the neonate to pick up and correct anorectal malformation improves long term outcome but this requires proper anal examination or it could be missed. We present and discuss a case of delayed diagnosis of congenital anal stenosis (a low anorectal anomaly with an imminent colonic perforation. Severe anal stenosis will always require examination under anesthesia with graded Hegar's dilatation followed by postoperative maintenance. The Hegar dilator is thus both diagnostic and therapeutic in congenital anal stenosis.

  2. Modeling of Random Delays in Networked Control Systems

    Directory of Open Access Journals (Sweden)

    Yuan Ge

    2013-01-01

    Full Text Available In networked control systems (NCSs, the presence of communication networks in control loops causes many imperfections such as random delays, packet losses, multipacket transmission, and packet disordering. In fact, random delays are usually the most important problems and challenges in NCSs because, to some extent, other problems are often caused by random delays. In order to compensate for random delays which may lead to performance degradation and instability of NCSs, it is necessary to establish the mathematical model of random delays before compensation. In this paper, four major delay models are surveyed including constant delay model, mutually independent stochastic delay model, Markov chain model, and hidden Markov model. In each delay model, some promising compensation methods of delays are also addressed.

  3. Effect of Nb on hydrogen-induced delayed fracture in high strength hot stamping steels

    International Nuclear Information System (INIS)

    The effect of Nb addition (0.022, 0.053, 0.078 wt%) on the hydrogen-induced delayed fracture resistance of 22MnB5 was studied by constant load test and electrochemical hydrogen permeation method. It is shown that the appropriate addition of Nb is beneficial to the improvement of the delayed fracture resistance of tested steel, especially when the steel contains high concentration of hydrogen, and the maximum delayed fracture resistance is obtained at a Nb content of 0.053%.The result of hydrogen permeation test shows that the diffusion coefficient of hydrogen in the steel containing niobium is lower than that in steel without niobium, which indicates that it is harder for hydrogen in the steels containing niobium to diffuse and aggregate. In addition, the reason for Nb improving the delayed fracture resistance of steels is discussed from two aspects: hydrogen trap effect and grain refinement effect. The analysis shows that the main reason leading to the improvement of the delayed fracture resistance is the hydrogen trapping effect of NbC while the grain refinement effect of Nb(C,N) secondary

  4. Effect of Nb on hydrogen-induced delayed fracture in high strength hot stamping steels

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Shiqi [School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083 (China); College of Mechanical Engineering, Yangtze University, Jingzhou 434023 (China); Huang, Yunhua, E-mail: huangyh@mater.ustb.edu.cn [School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083 (China); Sun, Bintang, E-mail: bingtangsun@ustb.edu.cn [School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083 (China); Liao, Qingliang [School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083 (China); Lu, Hongzhou [CITIC Metal Co. Ltd., Room 1901, Capital Mansion 6, Xin Yuan Nanlu, Chaoyang District, Beijing 100004 (China); The School of Resources and Environmental Engineering, East China University of Science and Technology, Meilong road 130, Xujiahui District, Shanghai 200237 (China); Jian, Bian [Niobium Tech Asia, 068898 Singapore (Singapore); Mohrbacher, Hardy [NiobelCon bvba, 2970 Schilde (Belgium); Zhang, Wei; Guo, Aimin [CITIC Metal Co. Ltd., Room 1901, Capital Mansion 6, Xin Yuan Nanlu, Chaoyang District, Beijing 100004 (China); Zhang, Yue [School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083 (China); The State Key Laboratory for Advanced Metals and Materials, University of Science and Technology Beijing, Beijing 100083 (China)

    2015-02-25

    The effect of Nb addition (0.022, 0.053, 0.078 wt%) on the hydrogen-induced delayed fracture resistance of 22MnB5 was studied by constant load test and electrochemical hydrogen permeation method. It is shown that the appropriate addition of Nb is beneficial to the improvement of the delayed fracture resistance of tested steel, especially when the steel contains high concentration of hydrogen, and the maximum delayed fracture resistance is obtained at a Nb content of 0.053%.The result of hydrogen permeation test shows that the diffusion coefficient of hydrogen in the steel containing niobium is lower than that in steel without niobium, which indicates that it is harder for hydrogen in the steels containing niobium to diffuse and aggregate. In addition, the reason for Nb improving the delayed fracture resistance of steels is discussed from two aspects: hydrogen trap effect and grain refinement effect. The analysis shows that the main reason leading to the improvement of the delayed fracture resistance is the hydrogen trapping effect of NbC while the grain refinement effect of Nb(C,N) secondary.

  5. Timing of autumn bird migration under climate change: advances in long-distance migrants, delays in short-distance migrants

    Science.gov (United States)

    Jenni, L.; Kery, M.

    2003-01-01

    As a response to increasing spring temperature in temperate regions in recent years, populations of many plant and animal species, including migratory birds, have advanced the seasonal start of their reproduction or growth. However, the effects of climate changes on subsequent events of the annual cycle remain poorly understood. We investigated long-term changes in the timing of autumn migration in birds, a key event in the annual cycle limiting the reproductive period. Using data spanning a 42-year period, we analysed long-term changes in the passage of 65 species of migratory birds through Western Europe. The autumn passage of migrants wintering south of the Sahara has advanced in recent years, presumably as a result of selection pressure to cross the Sahel before its seasonal dry period. In contrast, migrants wintering north of the Sahara have delayed autumn passage. In addition, species with a variable rather than a fixed number of broods per year have delayed passage, possibly because they are free to attempt more broods. Recent climate changes seem to have a simple unidirectional effect on the seasonal onset of reproduction, but complex and opposing effects on the timing of subsequent events in the annual cycle, depending on the ecology and life history of a species. This complicates predictions of overall effects of global warming on avian communities.

  6. Prioritization of Delay Factors for NPP Construction Risk in International Project by Using AHP Methodology

    Energy Technology Data Exchange (ETDEWEB)

    Hossen, Muhammed Mufazzal; Kang, Sunkoo; Kim, Jonghyun [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2014-10-15

    It is crucial for the nuclear power plant project decision makers and management personnel to identify the actual factors of construction delay and their ranking in order to take preventive actions. NPP project is complex in nature and the construction phase is one of the most key phase which is subject to many factors result from many sources. From experience, nuclear projects have faced challenges similar to other complex mega projects with additional nuclear specific issues and life time cost of nuclear reactor is concentrated upfront as capital cost, and therefore delays in construction may become intolerable in terms of both lost revenues and interest on the capital. Budget over-runs and delays on next generation new build nuclear projects in recent years clearly demonstrate that the nuclear industry continues to repeat its failed management and project control processes of the past. Similar to major infra-structure projects, actual completion times can vary substantially from initial estimates but this uncertainty is too crucial to the nuclear industry due to high levels of capital at risk, for every year a project is delayed the levelized cost of electricity increases by approximately 8-10%. causes of delay, to develop a generalized AHP model for delay factors, and to prioritize the risk in different factors in various levels of construction phase in international turnkey NPP project. This paper describes and prioritizes Nuclear Power Plant (NPP) construction schedule delay factor for turnkey international project. This study also determines the different party's importance in percentage behind the construction schedule delay of NPP which constitutes main contractor (28.4%), regulatory authority (27.3%), financial and country factor (23.5%), and utility (20.8%). Decision makers of nuclear industry can understand the significance of different factors on NPP construction phase and they can apply risk informed decision making to avoid unexpected

  7. Advanced X-Ray Astrophysics Facility Delivery Delayed

    Science.gov (United States)

    1997-12-01

    TRW Space and Electronics Group, Redondo Beach, CA, has notified NASA that it will be unable to deliver the Advanced X-ray Astrophysics Facility (AXAF) to NASA's Kennedy Space Center, FL, on June 1, 1998, as required by contract, because it has experienced delays in assembly and testing of the facility. TRW is NASA's prime contractor for the observatory. NASA and contractor officials met at NASA Headquarters in Washington, DC, this week to discuss the issue. While no new delivery date was agreed upon, the agency has directed TRW to develop a plan of action that would show how the contractor can minimize impact to the June 1 delivery. Although a delay in delivery could delay the launch, currently scheduled for August 1998 aboard Space Shuttle Columbia's STS-93 mission, and could result in additional program costs, the exact impact is not yet known. "The delay in delivery of the observatory is unfortunate," said Fred Wojtalik, NASA Marshall Space Flight Center observatory projects office manager in Huntsville, AL. "However, our first priority is to launch a world-class observatory which has been thoroughly tested and meets all requirements. We will work closely with TRW to ensure that happens." The delay is primarily due to TRW's difficulty in configuring and programming its Integrated Spacecraft Automated Test System to test the observatory before it is delivered to NASA. The Advanced X-ray Astrophysics Facility is expected to play a vital role in answering fundamental questions about the universe, including its age and size, and will probe the nature and amounts of so-called "dark matter," providing unique insight into one of nature's great puzzles. The observatory also will allow scientists to see and measure the details of hot gas clouds in clusters of galaxies; observe X-rays generated when stars are torn apart by the incredibly strong gravity around massive black holes in the centers of galaxies; and provide images that will help understand how exploding stars

  8. Transformation of Breast Reconstruction via Additive Biomanufacturing.

    Science.gov (United States)

    Chhaya, Mohit P; Balmayor, Elizabeth R; Hutmacher, Dietmar W; Schantz, Jan-Thorsten

    2016-01-01

    Adipose tissue engineering offers a promising alternative to current breast reconstruction options. However, the conventional approach of using a scaffold in combination with adipose-derived precursor cells poses several problems in terms of scalability and hence clinical feasibility. Following the body-as-a-bioreactor approach, this study proposes a unique concept of delayed fat injection into an additive biomanufactured and custom-made scaffold. Three study groups were evaluated: Empty scaffold, Scaffold containing 4 cm(3) lipoaspirate and Empty scaffold +2-week prevascularisation period. In group 3, of prevascularisation, 4 cm(3) of lipoaspirate was injected into scaffolds after 2 weeks. Using a well-characterised additive biomanufacturing technology platform, patient-specific scaffolds made of medical-grade-polycaprolactone were designed and fabricated. Scaffolds were implanted in subglandular pockets in immunocompetent minipigs (n = 4) for 24-weeks. Angiogenesis and adipose tissue regeneration were observed in all constructs. Histological evaluation showed that the prevascularisation + lipoaspirate group had the highest relative area of adipose tissue (47.32% ± 4.12) which was significantly higher than both lipoaspirate-only (39.67% ± 2.04) and empty control group (8.31% ± 8.94) and similar to native breast tissue (44.97% ± 14.12). This large preclinical animal study provides proof-of-principle that the clinically applicable prevascularisation and delayed fat-injection techniques can be used for regeneration of large volumes of adipose tissue. PMID:27301425

  9. Examination of InSAR tropospheric delay correction with JRA-55 reanalysis data

    Science.gov (United States)

    Kinoshita, Y.; Furuya, M.

    2015-12-01

    Interferometric Synthetic Aperture Radar (InSAR) phase signal contains not only surface deformations but also propagation delays due to Earth's atmosphere, which is the principal limiting factor for InSAR application of small deformation with amplitude of a few centimeters or less. Bevis et al. (1992) showed that the tropospheric delay consists of the hydrostatic delay due to dry gases and the wet delay due to water vapor. Previous studies proposed correction methods which used GNSS delay data or numerical weather model outputs. However, it is still insignificant for detecting small surface deformation. Jolivet et al. (2014) showed that reanalysis data like ECMWF Interim Re-Analysis (ERA-Interim) data is useful to mitigate topography-correlated tropospheric delay from InSAR data. However, previous studies used only one of the model data as a case study and didn't apply the correction to other areas. In this study we examined an effect of the tropospheric delay correction with Japanese 55-year reanalysis (JRA-55) data (Kobayashi et al., 2015). The horizontal resolution of JRA-55 is TL319 (approximately 60 km) and has 60 vertical layers. In addition, we estimated the tropospheric delay with ERA-Interim data for comparison. SAR data used were derived from ALOS/PALSAR around Nagoya prefecture (Path-Frame: 411-690). To avoid the spatial decorrelation, interferometric pairs with the perpendicular baseline of less 3000 m were generated. As a result, 309 interferograms were generated from 28 SAR single-look complex images. In consequence of the tropospheric delay correction with JRA-55 and ERA-Interim data, the averaged standard deviation of all interferograms slightly reduced from 1.26716 cm to 1.25231 cm by JRA-55 and slightly increased to 1.26797 cm by ERA-Interim. We further examined the correction effect when dividing the estimated delay into the hydrostatic component and the wet component. These results showed that JRA-55 corrected these delays rather than ERA

  10. A Robust and Multi-Weighted Approach to Estimating Topographically Correlated Tropospheric Delays in Radar Interferograms.

    Science.gov (United States)

    Zhu, Bangyan; Li, Jiancheng; Chu, Zhengwei; Tang, Wei; Wang, Bin; Li, Dawei

    2016-01-01

    Spatial and temporal variations in the vertical stratification of the troposphere introduce significant propagation delays in interferometric synthetic aperture radar (InSAR) observations. Observations of small amplitude surface deformations and regional subsidence rates are plagued by tropospheric delays, and strongly correlated with topographic height variations. Phase-based tropospheric correction techniques assuming a linear relationship between interferometric phase and topography have been exploited and developed, with mixed success. Producing robust estimates of tropospheric phase delay however plays a critical role in increasing the accuracy of InSAR measurements. Meanwhile, few phase-based correction methods account for the spatially variable tropospheric delay over lager study regions. Here, we present a robust and multi-weighted approach to estimate the correlation between phase and topography that is relatively insensitive to confounding processes such as regional subsidence over larger regions as well as under varying tropospheric conditions. An expanded form of robust least squares is introduced to estimate the spatially variable correlation between phase and topography by splitting the interferograms into multiple blocks. Within each block, correlation is robustly estimated from the band-filtered phase and topography. Phase-elevation ratios are multiply- weighted and extrapolated to each persistent scatter (PS) pixel. We applied the proposed method to Envisat ASAR images over the Southern California area, USA, and found that our method mitigated the atmospheric noise better than the conventional phase-based method. The corrected ground surface deformation agreed better with those measured from GPS. PMID:27420066

  11. A Robust and Multi-Weighted Approach to Estimating Topographically Correlated Tropospheric Delays in Radar Interferograms

    Directory of Open Access Journals (Sweden)

    Bangyan Zhu

    2016-07-01

    Full Text Available Spatial and temporal variations in the vertical stratification of the troposphere introduce significant propagation delays in interferometric synthetic aperture radar (InSAR observations. Observations of small amplitude surface deformations and regional subsidence rates are plagued by tropospheric delays, and strongly correlated with topographic height variations. Phase-based tropospheric correction techniques assuming a linear relationship between interferometric phase and topography have been exploited and developed, with mixed success. Producing robust estimates of tropospheric phase delay however plays a critical role in increasing the accuracy of InSAR measurements. Meanwhile, few phase-based correction methods account for the spatially variable tropospheric delay over lager study regions. Here, we present a robust and multi-weighted approach to estimate the correlation between phase and topography that is relatively insensitive to confounding processes such as regional subsidence over larger regions as well as under varying tropospheric conditions. An expanded form of robust least squares is introduced to estimate the spatially variable correlation between phase and topography by splitting the interferograms into multiple blocks. Within each block, correlation is robustly estimated from the band-filtered phase and topography. Phase-elevation ratios are multiply- weighted and extrapolated to each persistent scatter (PS pixel. We applied the proposed method to Envisat ASAR images over the Southern California area, USA, and found that our method mitigated the atmospheric noise better than the conventional phase-based method. The corrected ground surface deformation agreed better with those measured from GPS.

  12. A Robust and Multi-Weighted Approach to Estimating Topographically Correlated Tropospheric Delays in Radar Interferograms

    Science.gov (United States)

    Zhu, Bangyan; Li, Jiancheng; Chu, Zhengwei; Tang, Wei; Wang, Bin; Li, Dawei

    2016-01-01

    Spatial and temporal variations in the vertical stratification of the troposphere introduce significant propagation delays in interferometric synthetic aperture radar (InSAR) observations. Observations of small amplitude surface deformations and regional subsidence rates are plagued by tropospheric delays, and strongly correlated with topographic height variations. Phase-based tropospheric correction techniques assuming a linear relationship between interferometric phase and topography have been exploited and developed, with mixed success. Producing robust estimates of tropospheric phase delay however plays a critical role in increasing the accuracy of InSAR measurements. Meanwhile, few phase-based correction methods account for the spatially variable tropospheric delay over lager study regions. Here, we present a robust and multi-weighted approach to estimate the correlation between phase and topography that is relatively insensitive to confounding processes such as regional subsidence over larger regions as well as under varying tropospheric conditions. An expanded form of robust least squares is introduced to estimate the spatially variable correlation between phase and topography by splitting the interferograms into multiple blocks. Within each block, correlation is robustly estimated from the band-filtered phase and topography. Phase-elevation ratios are multiply- weighted and extrapolated to each persistent scatter (PS) pixel. We applied the proposed method to Envisat ASAR images over the Southern California area, USA, and found that our method mitigated the atmospheric noise better than the conventional phase-based method. The corrected ground surface deformation agreed better with those measured from GPS. PMID:27420066

  13. Lupus vulgaris diagnosed after 37 years: a case of delayed diagnosis.

    Science.gov (United States)

    Turan, Enver; Yurt, Nurdan; Yesilova, Yavuz; Celik, Ozgur Ilhan

    2012-05-15

    Lupus vulgaris is the most common chronic, progressive form of cutaneous tuberculosis. Lesions are generally solitary and found on the head and neck region. Cutaneous tuberculosis can present with different clinical appearances. Therefore, it does not necessarily have characteristic findings and can be difficult to diagnose. Although there were typical clinical findings, the diagnosis of our case was delayed because of its asymptomatic course.

  14. Microwave delay characteristics of Cassegrainian antennas. [signal distortion analysis

    Science.gov (United States)

    Cha, A. G.; Otoshi, T. Y.; Rusch, W. V. T.

    1978-01-01

    A technique is presented in which the time an RF signal is delayed in propagating through a Cassegrain antenna is determined. The technique utilizes the group delay time and the envelope delay time as found from the antenna transfer function. The calculations show that a focused antenna is basically a nondispersive device whose delay time may be found from an optics formula. Small subreflector displacements result in significant delay changes requiring calibrations for many applications.

  15. Asymptotic properties of the spectrum of neutral delay differential equations

    OpenAIRE

    Kyrychko, Y. N.; Blyuss, K B; Hoevel, P.; Schoell, E.

    2012-01-01

    Spectral properties and transition to instability in neutral delay differential equations are investigated in the limit of large delay. An approximation of the upper boundary of stability is found and compared to an analytically derived exact stability boundary. The approximate and exact stability borders agree quite well for the large time delay, and the inclusion of a time-delayed velocity feedback improves this agreement for small delays. Theoretical results are complemented by a numerical...

  16. Constraints on interacting dark energy from time delay lenses

    Science.gov (United States)

    Pan, Yu; Cao, Shuo; Li, Li

    2016-10-01

    We use the time delay measurements between multiple images of lensed sources in 18 strongly gravitationally lensed (SGL) systems to put additional constraints on three phenomenological interaction models for dark energy (DE) and dark matter (DM). The compatibility among the fits on the three models seems to imply that the coupling between DE and DM is a small value close to zero, which is compatible with the previous results for constraining interacting DE parameters. We find that, among the three interacting DE models, the γmIDE model with the interaction term Q proportional to the energy density of DM provides relatively better fits to recent observations. However, the coincidence problem is still very severe in the framework of three interacting DE models, since the fitting results do not show any preference for a nonzero coupling between DE and DM. More importantly, we have studied the significance of the current strong lensing data in deriving the interacting information between dark sectors, which highlights the importance of strong lensing time delay measurements to provide additional observational fits on alternative cosmological models.

  17. Wet Tropospheric Zenith Delay and Precipitable Water Vapor Estimated From Radiosonde Data

    Science.gov (United States)

    Deniz, Ilke; Mekik, Cetin

    2014-05-01

    Continuously Operating GPS Networks are being used for meteorological and climate research. The wet tropospheric zenith delays derived from these networks are converted to the precipitable water vapour. Thus, an important data is produced for the development of numerical models of the tropospheric zenith delay and the precipitable water vapor for local, regional and global areas and for the meteorology and climate research. The radiosonde observation data and the results derived from them are taken as references for the determination of accurate and reliable transformation parameters between the wet tropospheric zenith delay and the precipitable water vapor. In this study, an algorithm is developed using Matlab to calculate the values of the weighted mean temperature (Tm), the wet tropospheric zenith delay, and the precipitable water vapor from the parameters of radiosonde profile data such as height (h), temperature (T), dew point temperature (Td), pressure (p) and humidity (H). The results of the algorithm using the parameters from Istanbul, Ankara, Diyarbakir and Samsun radiosonde stations are also given. The radiosonde temperature profile values are modelled using polynomial by the least squares method, because it is easy to integrate the polynomial as a function of height. The degree of the polynomial is taken as 5-8 and the precision of modelling depending on the amount of water vapor is found ±0.1-2.0 K. In addition, the surface temperature (Ts) is obtained by using estimated temperature values. The values of water vapor pressure (e), one of the most important parameter in the meteorological research, are calculated by Tetens equations for water and ice separately. In this calculation, the values of wet bulb temperature (Tw) are found by using iteration from the model given by Danish Meteorological Institute. Henceforth, the values of (e/T) and (e/T2) are modelled as a function of height using the polynomial again. Definite integrals are calculated from the

  18. Radiation induced early delayed changes in mice brain: a 1h MRS and behavioral evaluation study

    International Nuclear Information System (INIS)

    Radiation induced CNS injury can be classified as acute, early delayed and late delayed. Most of the studies suggest that acute injury is reversible whereas early delayed and late delayed injury is irreversible leading to metabolic and cognitive impairment. Extensive research has been carried out on cranial radiation induced early and late delayed changes, there are no reports on whole body radiation induced early and delayed changes. The present study was designed to observe early delayed effects of radiation during whole body radiation exposure. A total of 20 C57 male mice were divided in two groups of 10 animals each. One group was exposed to a dose of 5 Gy whole body radiation through Tele 60Co irradiation facility with source operating at 2.496 Gy/min, while other group served as sham irradiated control. Behavioral and MR spectroscopy was carried out 3 months post irradiation. Behavioral parameters such as locomotor activity and working memory were evaluated first then followed by MR spectroscopy at 7T animal MRI system. For MRS, voxel was localised in the cortex-hippocampus region of mouse brain. MR spectra were acquired using PRESS sequence, FID was processed using LC model for quantitation. The data showed impaired cognitive functions and altered metabolite levels during early delayed phase of whole body radiation induced injury. In behavioural experiments, there was a significant impairment in the cognitive as well as exploratory functions at 3 months post irradiation in irradiated group as compared to controls. MRS results explained changes in mI, glutamine and glx levels in irradiated animals compared to controls. Altered mI level has been found to be associated with reduced cognitive abilities in many brain disorders including MCI and Alzheimer's disease. The findings of this study suggest that whole body radiation exposure may have long lasting effect on the cognitive performance. (author)

  19. Dynamics of delayed-coupled chaotic logistic maps: Influence of network topology, connectivity and delay times

    Indian Academy of Sciences (India)

    Arturo C Martí; Marcelo Ponce; Cristina Masoller

    2008-06-01

    We review our recent work on the synchronization of a network of delay-coupled maps, focusing on the interplay of the network topology and the delay times that take into account the finite velocity of propagation of interactions. We assume that the elements of the network are identical ( logistic maps in the regime where the individual maps, without coupling, evolve in a chaotic orbit) and that the coupling strengths are uniform throughout the network. We show that if the delay times are su±ciently heterogeneous, for adequate coupling strength the network synchronizes in a spatially homogeneous steady state, which is unstable for the individual maps without coupling. This synchronization behavior is referred to as `suppression of chaos by random delays' and is in contrast with the synchronization when all the interaction delay times are homogeneous, because with homogeneous delays the network synchronizes in a state where the elements display in-phase time-periodic or chaotic oscillations. We analyze the influence of the network topology considering four different types of networks: two regular (a ring-type and a ring-type with a central node) and two random (free-scale Barabasi-Albert and small-world Newman-Watts). We find that when the delay times are sufficiently heterogeneous the synchronization behavior is largely independent of the network topology but depends on the network's connectivity, i.e., on the average number of neighbors per node.

  20. Time-Delay Interferometry with optical frequency comb

    CERN Document Server

    Tinto, Massimo

    2015-01-01

    Heterodyne laser phase measurements in a space-based gravitational wave interferometer are degraded by the phase fluctuations of the onboard clocks, resulting in unacceptable sensitivity performance levels of the interferometric data. In order to calibrate out the clock phase noises it has been previously suggested that additional inter-spacecraft phase measurements must be performed by modulating the laser beams. This technique, however, considerably increases system complexity and probability of subsystem failure. With the advent of self-referenced optical frequency combs, it is possible to generate the heterodyne microwave signal that is coherently referenced to the onboard laser. We show in this case that the microwave noise can be cancelled directly by applying modified second-generation Time-Delay Interferometric combinations to the heterodyne phase measurements. This approach avoids use of modulated laser beams as well as the need of additional ultra-stable oscillator clocks.