WorldWideScience

Sample records for ada

  1. Ada & the Analytical Engine.

    Science.gov (United States)

    Freeman, Elisabeth

    1996-01-01

    Presents a brief history of Ada Byron King, Countess of Lovelace, focusing on her primary role in the development of the Analytical Engine--the world's first computer. Describes the Ada Project (TAP), a centralized World Wide Web site that serves as a clearinghouse for information related to women in computing, and provides a Web address for…

  2. Ada Test and Evaluation.

    Science.gov (United States)

    1980-05-01

    Lady Lovelace , the daughter of the poet, Lord Byron. Ada was Charles Babbage’s programmer, Babbage being the inventor of the first mechanical...34 O-07 0 ARFOCERIGTAEOAUIAL LABS RIGHTPATTERSON AFB OH F/G 9/2 ADA TEST AND EVALUATION.(U) MAY BO A J SCARPELLI UNCLASSIFIED AFWAL-TR-BO-1024 NL E...llEllllEIlE III HA i28 5__ BIH~~ ~ 2 __I.,11 LZ AFAL-TR-80-1024 Ada TEST AND EVALUATION Alfred J. Scarpelli System Technology Branch Systen Avionics

  3. OLDER DRIVERS AND ADAS

    Directory of Open Access Journals (Sweden)

    Ragnhild J. DAVIDSE

    2006-01-01

    Next, based on the available literature, relevant ADAS are discussed in terms of their availability, their effects on safety and the willingness of older drivers to use and buy them. One of the conclusions is that only very few of the types of support that are thought to be most beneficial to the safety of older drivers are provided by the ADAS that are currently available.

  4. Transition to Ada

    Science.gov (United States)

    1993-02-01

    from design to implementation through integration with Cadre’s Ada Source Builder (ASB) and Design Sensitive Editor ( DSE ). When used with the ASG...inserted into the generated code using the DSE , but only within the code frames. The DSE automatically detects Ada syntax errors, and may be configured...Contains summaries of current approaches to likely problems, indications of deficiencies in existing knowledge, and checklists of questions to ask when

  5. Software engineering capability for Ada (GRASP/Ada Tool)

    Science.gov (United States)

    Cross, James H., II

    1995-01-01

    The GRASP/Ada project (Graphical Representations of Algorithms, Structures, and Processes for Ada) has successfully created and prototyped a new algorithmic level graphical representation for Ada software, the Control Structure Diagram (CSD). The primary impetus for creation of the CSD was to improve the comprehension efficiency of Ada software and, as a result, improve reliability and reduce costs. The emphasis has been on the automatic generation of the CSD from Ada PDL or source code to support reverse engineering and maintenance. The CSD has the potential to replace traditional prettyprinted Ada Source code. A new Motif compliant graphical user interface has been developed for the GRASP/Ada prototype.

  6. Ada Implementation Guide. Software Engineering With Ada. Volume 2

    Science.gov (United States)

    1994-04-01

    A-533 A.3.2 Publications ..................................... A-54 AdaDATA Newsletter .............................. A-54 Ada Letters ...and major modifications I GENINTRO 10/10/91 2048 Cover letter to accompany General Information Packet GLOSSARY 8/11/90 47056 Ada -related terms and...international standard LADY-LOV 11/25/91 10240 Article on life of Ada Lovelace by Carol L. James and Duncan E. Morrill with note on the naming of the Ada

  7. Toward ADA: The Continuing Development of an ADA Compiler.

    Science.gov (United States)

    1981-12-01

    the compiler. 1.2 Background Augusta Ada Byron, Countess Lovelace , the daughter of the poet Lord Byron, was a colleague of Charles Babbage and author of...compiler would handle. The AFIT- Ada compiler only processed the characters of the restricted character set. Any character other than upper-case letters ...AD-A115 479 AIR FORCE INST OF TECH WRZIkST-PATTERSON AFB OH SCHOO--ETC F/G 9/2 TOWARD ADA : THE CONTINUING DEVELOPMENT OF AN ADA COMP!LER.(U’ DEC 81 P

  8. ADAS Update and Maintainability

    Science.gov (United States)

    Watson, Leela R.

    2010-01-01

    Since 2000, both the National Weather Service Melbourne (NWS MLB) and the Spaceflight Meteorology Group (SMG) have used a local data integration system (LOIS) as part of their forecast and warning operations. The original LOIS was developed by the Applied Meteorology Unit (AMU) in 1998 (Manobianco and Case 1998) and has undergone subsequent improvements. Each has benefited from three-dimensional (3-D) analyses that are delivered to forecasters every 15 minutes across the peninsula of Florida. The intent is to generate products that enhance short-range weather forecasts issued in support of NWS MLB and SMG operational requirements within East Central Florida. The current LDIS uses the Advanced Regional Prediction System (ARPS) Data Analysis System (AD AS) package as its core, which integrates a wide variety of national, regional, and local observational data sets. It assimilates all available real-time data within its domain and is run at a finer spatial and temporal resolution than current national or regional-scale analysis packages. As such, it provides local forecasters with a more comprehensive understanding of evolving fine-scale weather features. Over the years, the LDIS has become problematic to maintain since it depends on AMU-developed shell scripts that were written for an earlier version of the ADAS software. The goals of this task were to update the NWS MLB/SMG LDIS with the latest version of ADAS, incorporate new sources of observational data, and upgrade and modify the AMU-developed shell scripts written to govern the system. In addition, the previously developed ADAS graphical user interface (GUI) was updated. Operationally, these upgrades will result in more accurate depictions of the current local environment to help with short-range weather forecasting applications, while also offering an improved initialization for local versions of the Weather Research and Forecasting (WRF) model used by both groups.

  9. Ada in the PAX Environment

    Science.gov (United States)

    1994-04-01

    individual styles and talents, it is argued. Furthermore, DOD believes that standardizat on will turn programming from an art into a discipline...called IntegrAda . The AETECH environment is probably r " most developer-friendly of all the Ada compilers for microcomputers. The AETECH compiler

  10. Ada Linear-Algebra Program

    Science.gov (United States)

    Klumpp, A. R.; Lawson, C. L.

    1988-01-01

    Routines provided for common scalar, vector, matrix, and quaternion operations. Computer program extends Ada programming language to include linear-algebra capabilities similar to HAS/S programming language. Designed for such avionics applications as software for Space Station.

  11. Ada (Trade Name) Bibliography. Volume 3.

    Science.gov (United States)

    1986-02-01

    maintenance of the Ada language. (author) INDEX TERMS STANDARDS . . . Ada Bibliography Volume Ill 117 ADA PUBLICATIONS ROMANOWSKY . HELEN DOCUMENT NUMBER...ENVIRONMENT ROGERS, W.J., u. OF WAIKATO. HAMILTON NEW ZEALAND 3316 -01 THE DESIGN OF A VIRTUAL MACHINE FOR ADA ROMANOWSKY , HELEN, ROCKWELL INT’L. MS124

  12. Multiprocessor performance modeling with ADAS

    Science.gov (United States)

    Hayes, Paul J.; Andrews, Asa M.

    1989-01-01

    A graph managing strategy referred to as the Algorithm to Architecture Mapping Model (ATAMM) appears useful for the time-optimized execution of application algorithm graphs in embedded multiprocessors and for the performance prediction of graph designs. This paper reports the modeling of ATAMM in the Architecture Design and Assessment System (ADAS) to make an independent verification of ATAMM's performance prediction capability and to provide a user framework for the evaluation of arbitrary algorithm graphs. Following an overview of ATAMM and its major functional rules are descriptions of the ADAS model of ATAMM, methods to enter an arbitrary graph into the model, and techniques to analyze the simulation results. The performance of a 7-node graph example is evaluated using the ADAS model and verifies the ATAMM concept by substantiating previously published performance results.

  13. Ada (Trademark) Joint Program Office Objectives and Progress -- through 1983.

    Science.gov (United States)

    1984-09-01

    Ada Byron, the countess of Lovelace . On 12 December 1980, the Under Secretary of Defense for Research and Engineering established the Ada ...language for DOD was named Ada , in honor of Augusta Ada Byron, the Countess of Lovelace . On 12 December 1980, the Under Secretary of Defense for Research... Ada Europe, JUG Ada and Ada LETTERS . Ada LETTERS is published bimonthly by SIGAda, and contains articles written by the AJPO and other Ada

  14. The Utility of Ada for Army Modeling

    Science.gov (United States)

    1990-04-10

    34 Ada " for Ada Lovelace (1815-1851), a mathematician who worked with Charles Babbage on his difference and analytic engines.9 Later in 1979, the HOLWG...OF ADA FOR ARMY MODELING BY COLONEL MICHAEL L. YOCOM DISTRIBUTION STATEMENT A: Approved for publie releases distribution is unlimited. 1% LF-, EC TE...TITLE (ad Subtitle) a. TYPE OF REPORT & PERIOD COVERED The Utility of Ada for Army Modeling Individual Study Project 6 PERFORMING ORG. REPORT NUMBER

  15. Software unit testing in Ada environment

    Science.gov (United States)

    Warnock, Glenn

    1986-01-01

    A validation procedure for the Ada binding of the Graphical Kernel System (GKS) is being developed. PRIOR Data Sciences is also producing a version of the GKS written in Ada. These major software engineering projects will provide an opportunity to demonstrate a sound approach for software testing in an Ada environment. The GKS/Ada validation capability will be a collection of test programs and data, and test management guidelines. These products will be used to assess the correctness, completeness, and efficiency of any GKS/Ada implementation. The GKS/Ada developers will be able to obtain the validation software for their own use. It is anticipated that this validation software will eventually be taken over by an independent standards body to provide objective assessments of GKS/Ada implementations, using an approach similar to the validation testing currently applied to Ada compilers. In the meantime, if requested, this validation software will be used to assess GKS/Ada products. The second project, implementation of GKS using the Ada language, is a conventional software engineering tasks. It represents a large body of Ada code and has some interesting testing problems associated with automatic testing of graphics routines. Here the normal test practices which include automated regression testing, independent quality assistance, test configuration management, and the application of software quality metrics will be employed. The software testing methods emphasize quality enhancement and automated procedures. Ada makes some aspects of testing easier, and introduces some concerns. These issues are addressed.

  16. The testability of Ada programs

    Science.gov (United States)

    Auty, David; Cohen, Norman H.

    1986-01-01

    Software development for NASA's Space Station poses a significant problem; considered the most difficult by some. The difficulty is the magnitude and complexity of the required software. The concerns raised by consideration of the requirements for testing and checkout procedures for the Space Station software are addressed. In particular, it addresses the use of Ada in the development of widely distributed yet closely coordinated processing.

  17. Ada and cyclic runtime scheduling

    Science.gov (United States)

    Hood, Philip E.

    1986-01-01

    An important issue that must be faced while introducing Ada into the real time world is efficient and prodictable runtime behavior. One of the most effective methods employed during the traditional design of a real time system is the cyclic executive. The role cyclic scheduling might play in an Ada application in terms of currently available implementations and in terms of implementations that might be developed especially to support real time system development is examined. The cyclic executive solves many of the problems faced by real time designers, resulting in a system for which it is relatively easy to achieve approporiate timing behavior. Unfortunately a cyclic executive carries with it a very high maintenance penalty over the lifetime of the software that is schedules. Additionally, these cyclic systems tend to be quite fragil when any aspect of the system changes. The findings are presented of an ongoing SofTech investigation into Ada methods for real time system development. The topics covered include a description of the costs involved in using cyclic schedulers, the sources of these costs, and measures for future systems to avoid these costs without giving up the runtime performance of a cyclic system.

  18. QUEST/Ada (Query Utility Environment for Software Testing) of Ada: The development of a program analysis environment for Ada

    Science.gov (United States)

    Brown, David B.

    1988-01-01

    A history of the Query Utility Environment for Software Testing (QUEST)/Ada is presented. A fairly comprehensive literature review which is targeted toward issues of Ada testing is given. The definition of the system structure and the high level interfaces are then presented. The design of the three major components is described. The QUEST/Ada IORL System Specifications to this point in time are included in the Appendix. A paper is also included in the appendix which gives statistical evidence of the validity of the test case generation approach which is being integrated into QUEST/Ada.

  19. Analysis of Ada as a prototyping language

    Science.gov (United States)

    Holloway, C. Michael

    1987-01-01

    This paper examines the suitability of Ada as a language for developing software prototypes. The differences between software prototypes and traditional engineering prototypes are discussed; the approaches to software prototyping are identified. Ada's potential as a language for prototyping is evaluated according to the writability, expressiveness, and flexibility of the language; Ada is found to be inadequate as a prototyping language because it lacks writability and expressiveness. Possible approaches to improving the expressiveness of the language are discussed.

  20. A Comparison of Ada 83 and C++

    Science.gov (United States)

    1991-06-01

    developing large, complex, software systems with long lifetimes. Those interviewed for this study who are familiar with both Ada and C++ believe that Ada is...with those who are familiar with both languages, there was a clear preference for using Ada for large complex systems with long lifetimes. These...University, December 1990 Additions by Nelson H. Weiderman, June 1991. Chile Empresa Nacional de Aeronautica (ENAER), real-time avionics system, Data

  1. Ada training evaluation and recommendations from the Gamma Ray Observatory Ada Development Team

    International Nuclear Information System (INIS)

    1985-10-01

    The Ada training experiences of the Gamma Ray Observatory Ada development team are related, and recommendations are made concerning future Ada training for software developers. Training methods are evaluated, deficiencies in the training program are noted, and a recommended approach, including course outline, time allocation, and reference materials, is offered

  2. A small evaluation suite for Ada compilers

    Science.gov (United States)

    Wilke, Randy; Roy, Daniel M.

    1986-01-01

    After completing a small Ada pilot project (OCC simulator) for the Multi Satellite Operations Control Center (MSOCC) at Goddard last year, the use of Ada to develop OCCs was recommended. To help MSOCC transition toward Ada, a suite of about 100 evaluation programs was developed which can be used to assess Ada compilers. These programs compare the overall quality of the compilation system, compare the relative efficiencies of the compilers and the environments in which they work, and compare the size and execution speed of generated machine code. Another goal of the benchmark software was to provide MSOCC system developers with rough timing estimates for the purpose of predicting performance of future systems written in Ada.

  3. Experiences with Ada in an embedded system

    Science.gov (United States)

    Labaugh, Robert J.

    1988-01-01

    Recent experiences with using Ada in a real time environment are described. The application was the control system for an experimental robotic arm. The objectives of the effort were to experiment with developing embedded applications in Ada, evaluating the suitability of the language for the application, and determining the performance of the system. Additional objectives were to develop a control system based on the NASA/NBS Standard Reference Model for Telerobot Control System Architecture (NASREM) in Ada, and to experiment with the control laws and how to incorporate them into the NASREM architecture.

  4. Software engineering and Ada in design

    Science.gov (United States)

    Oneill, Don

    1986-01-01

    Modern software engineering promises significant reductions in software costs and improvements in software quality. The Ada language is the focus for these software methodology and tool improvements. The IBM FSD approach, including the software engineering practices that guide the systematic design and development of software products and the management of the software process are examined. The revised Ada design language adaptation is revealed. This four level design methodology is detailed including the purpose of each level, the management strategy that integrates the software design activity with the program milestones, and the technical strategy that maps the Ada constructs to each level of design. A complete description of each design level is provided along with specific design language recording guidelines for each level. Finally, some testimony is offered on education, tools, architecture, and metrics resulting from project use of the four level Ada design language adaptation.

  5. New control system: IMAGIN supervision in ADA

    International Nuclear Information System (INIS)

    Maugeais, C.

    1991-01-01

    The structure, the initialization, the operating cycle, the different messages and the errors treatment of the new user oriented packages written in ADA language for IMAGIN software are presented. (A.B.). 2 figs

  6. Real-Time Ada Problem Solution Study

    Science.gov (United States)

    1989-03-24

    discussed in Chapter 13 of the Ada Language Reference Manual , a compiler vendor has some flexibility in determining a compiler implementation approach...Method - Tools Solution Timeframe - Short-term Solution Approach - Remedial Solution 2 - Use a compiler which provides "fast" interrupt procesoing . A...require some manual support to make them suitable for use in debugging an Ada application. Solution Method - Tools Solution Timeframe - Short-term Solution

  7. 49 CFR 37.123 - ADA paratransit eligibility: Standards.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false ADA paratransit eligibility: Standards. 37.123... INDIVIDUALS WITH DISABILITIES (ADA) Paratransit as a Complement to Fixed Route Service § 37.123 ADA... complementary paratransit service shall provide the service to the ADA paratransit eligible individuals...

  8. 49 CFR 37.125 - ADA paratransit eligibility: Process.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false ADA paratransit eligibility: Process. 37.125... INDIVIDUALS WITH DISABILITIES (ADA) Paratransit as a Complement to Fixed Route Service § 37.125 ADA... § 37.121 of this part shall establish a process for determining ADA paratransit eligibility. (a) The...

  9. ADASAGE, ADA Application Development System

    International Nuclear Information System (INIS)

    Taylor, M.; Russell, K.; Stewart, H.

    2001-01-01

    1 - Description of program or function: ADASAGE is an application development system designed to facilitate rapid and professional construction of applications written in Ada on microcomputers. ADASAGE applications may vary in size from small to large multi-program systems. ADASAGE consists of a collection of re-usable libraries for database management and form and report processing utilities having the following capabilities: basic universal type and function definitions; sequential file input/output; terminal and file input/output; DOS system command execution; data movement and fill; string manipulation; math libraries; bit manipulation; a relational database utility; data validation; menu form and window procedures; report generation; sort/merge, time, and date functions; sound production; editing; and index rebuilding. Each of the capabilities is integrated to allow the development of an efficient system. As an application is designed and developed, the desired ADASAGE capabilities are chosen and included along with any requirements unique to that application. 2 - Method of solution: All ADASAGE applications which use the database, forms (windows, menus, etc.), or reporting functions require a file with a suffix of .DFL. This file contains the database schema, the various forms and windows, and report definitions. The THOR editor is used to create and maintain the .DFL file. This editor operates on a file with the suffix .SRC and creates and edits schemes, forms, and report formats and compile the .SRC file into the .DFL file used by the application. The application will have unique requirements not satisfied by the selected utilities of ADASAGE. The code for these along with the code necessary to import and use the selected ADASAGE utilities constitutes the p rogrammed application . The completed application system will contain the .DFL file produced by the THOR editor, the required ADASAGE utilities, and the programmed application. During the course of

  10. An Embedded Rule-Based Diagnostic Expert System in Ada

    Science.gov (United States)

    Jones, Robert E.; Liberman, Eugene M.

    1992-01-01

    Ada is becoming an increasingly popular programming language for large Government-funded software projects. Ada with it portability, transportability, and maintainability lends itself well to today's complex programming environment. In addition, expert systems have also assumed a growing role in providing human-like reasoning capability expertise for computer systems. The integration is discussed of expert system technology with Ada programming language, especially a rule-based expert system using an ART-Ada (Automated Reasoning Tool for Ada) system shell. NASA Lewis was chosen as a beta test site for ART-Ada. The test was conducted by implementing the existing Autonomous Power EXpert System (APEX), a Lisp-based power expert system, in ART-Ada. Three components, the rule-based expert systems, a graphics user interface, and communications software make up SMART-Ada (Systems fault Management with ART-Ada). The rules were written in the ART-Ada development environment and converted to Ada source code. The graphics interface was developed with the Transportable Application Environment (TAE) Plus, which generates Ada source code to control graphics images. SMART-Ada communicates with a remote host to obtain either simulated or real data. The Ada source code generated with ART-Ada, TAE Plus, and communications code was incorporated into an Ada expert system that reads the data from a power distribution test bed, applies the rule to determine a fault, if one exists, and graphically displays it on the screen. The main objective, to conduct a beta test on the ART-Ada rule-based expert system shell, was achieved. The system is operational. New Ada tools will assist in future successful projects. ART-Ada is one such tool and is a viable alternative to the straight Ada code when an application requires a rule-based or knowledge-based approach.

  11. Ada Quality and Style: Guidelines for Professional Programmers

    Science.gov (United States)

    1991-01-01

    and Robert Mathis. Word processing was performed by Debra Morgan. Additional supporters included Bruce Barnes, Alex Blakemore, Terry Bollinger ...International 1985 Conference. pp. 14-16. Paris . BIBLIOGRAPHY ACVC (Ada Compiler Validation Capability). Ada Validation Facility, ASD/SIOL. Wright...Distributing Real-time Ada Programs Across Machines. Ada in Use, Proceedings of the Ada International Conference. pp. 14-16. Paris . Symbols acronym, 19

  12. Certification of Ada parts for reuse

    Science.gov (United States)

    Hansen, Gregory A.; Spaulding, S. D.; Edgar, Glenn

    1986-01-01

    One of the claims made by proponents of Ada is that Ada software is highly reusable. The fact that specifications are compiled and accessible would make reusability seem easily achievable. However, specifications give only a limited amount of information about a package; moreover, a specification cannot help determine whether a package worked, or how well it worked. This problem has led to the concept of certifying Ada parts for reuse; that is, determining the worthiness of a part as a reusable component. Issues that are critical to reuse are addressed: the characterization of part performance, design for reuse, and correct utilization of parts. Current areas of study beneficial in the development of a certification process are then addressed.

  13. Ada in Introductory Computer Science Courses

    Science.gov (United States)

    1993-01-01

    M2 111418111 1111111 I s%1 tems to des elop soaftware Systems for IM5. ONhalt oIf dt ufl’wae mownev b f "bs" arn .exti to k ,ulift la Ada. COMPUT...beftjobamdsodeckldthesespienicngamnug them. A celula 101110011ui systm Service in Ada& using an rmniticdawau dipay shows *I tatus. The systm objweaniiimd...liftt aftr of Fucal Nikkao Wirh. Some say Software i - , I, ced a pse-validaed ver. origina soitweim is coded. The idWa is to that Ads is the las gpat

  14. Atomic Data and Modelling for Fusion: the ADAS Project

    International Nuclear Information System (INIS)

    Summers, H. P.; O'Mullane, M. G.

    2011-01-01

    The paper is an update on the Atomic Data and Analysis Structure, ADAS, since ICAM-DATA06 and a forward look to its evolution in the next five years. ADAS is an international project supporting principally magnetic confinement fusion research. It has participant laboratories throughout the world, including ITER and all its partner countries. In parallel with ADAS, the ADAS-EU Project provides enhanced support for fusion research at Associated Laboratories and Universities in Europe and ITER. OPEN-ADAS, sponsored jointly by the ADAS Project and IAEA, is the mechanism for open access to principal ADAS atomic data classes and facilitating software for their use. EXTENDED-ADAS comprises a variety of special, integrated application software, beyond the purely atomic bounds of ADAS, tuned closely to specific diagnostic analyses and plasma models.The current scientific content and scope of these various ADAS and ADAS related activities are briefly reviewed. These span a number of themes including heavy element spectroscopy and models, charge exchange spectroscopy, beam emission spectroscopy and special features which provide a broad baseline of atomic modelling and support. Emphasis will be placed on 'lifting the fundamental data baseline'--a principal ADAS task for the next few years. This will include discussion of ADAS and ADAS-EU coordinated and shared activities and some of the methods being exploited.

  15. Ada in AI or AI in Ada. On developing a rationale for integration

    Science.gov (United States)

    Collard, Philippe E.; Goforth, Andre

    1988-01-01

    The use of Ada as an Artificial Intelligence (AI) language is gaining interest in the NASA Community, i.e., by parties who have a need to deploy Knowledge Based-Systems (KBS) compatible with the use of Ada as the software standard for the Space Station. A fair number of KBS and pseudo-KBS implementations in Ada exist today. Currently, no widely used guidelines exist to compare and evaluate these with one another. The lack of guidelines illustrates a fundamental problem inherent in trying to compare and evaluate implementations of any sort in languages that are procedural or imperative in style, such as Ada, with those in languages that are functional in style, such as Lisp. Discussed are the strengths and weakness of using Ada as an AI language and a preliminary analysis provided of factors needed for the development of criteria for the integration of these two families of languages and the environments in which they are implemented. The intent for developing such criteria is to have a logical rationale that may be used to guide the development of Ada tools and methodology to support KBS requirements, and to identify those AI technology components that may most readily and effectively be deployed in Ada.

  16. Gamma ray observatory dynamics simulator in Ada (GRODY)

    International Nuclear Information System (INIS)

    1990-09-01

    This experiment involved the parallel development of dynamics simulators for the Gamma Ray Observatory in both FORTRAN and Ada for the purpose of evaluating the applicability of Ada to the NASA/Goddard Space Flight Center's flight dynamics environment. The experiment successfully demonstrated that Ada is a viable, valuable technology for use in this environment. In addition to building a simulator, the Ada team evaluated training approaches, developed an Ada methodology appropriate to the flight dynamics environment, and established a baseline for evaluating future Ada projects

  17. New control system: ADA softwares organization

    International Nuclear Information System (INIS)

    David, L.

    1992-01-01

    On VAX/VMS, ADA compiler is integrated in a workshop of ACS software engineering which allows a coherent development by control of source and executable programs, by separation of applications in various levels of visibility and by management of existing links between different modules of a same application. (A.B.)

  18. LAS DOS TRÍADAS DEBEJARANO

    Directory of Open Access Journals (Sweden)

    Jorge Iván González

    Full Text Available El artículo diseute "dos tríadas" que propone Bejarano para calificar a la teoría económica actual. La primera tríada tiene que ver con el realismo, la pertinencia y la relevancia de la teoría. Y la segunda tríada con sus dimensiones política, institucional y moral. El artículo centra la atención en esta segunda tríada, argumentando que la teoría no es apolítica, ainstitucional y amoral como afirma Bejarano. El examen crítico de la posición de Bejarano se sustenta en algunas de las tesis de: Walras, Marshall, Hicks, vickrey, Samuelson y Arrow.This article discusses the "two triads" that Bejarano has proposed in order to describe present economic theory. The first triad refers to the realism, pertinence and relevance of the theory. The second triad to its political, institutional and moral dimension. The article centers its attention on this second triad, arguing that the theory is not apolitical, uninstitutional and amoral as Bejarano states. The critical examination of Bejarano's proposition is supported on thesis of Walras, Marshall, Hicks, Vickrey, Samuelson and Arrow.

  19. KYTC sidewalk and curb ramp inventory for ADA compliance.

    Science.gov (United States)

    2017-09-01

    The Americans with Disabilities Act of 1990 (ADA) requires that all public and private organizations providing services to the public ensure their facilities and infrastructure comply with regulations set forth therein. The ADA requires that a transi...

  20. Review of advanced driver assistance systems (ADAS)

    Science.gov (United States)

    Ziebinski, Adam; Cupek, Rafal; Grzechca, Damian; Chruszczyk, Lukas

    2017-11-01

    New cars can be equipped with many advanced safety solutions. Airbags, seatbelts and all of the essential passive safety parts are standard equipment. Now cars are often equipped with new advanced active safety systems that can prevent accidents. The functions of the Advanced Driver Assistance Systems are still growing. A review of the most popular available technologies used in ADAS and descriptions of their application areas are discussed in this paper.

  1. Evolving impact of Ada on a production software environment

    Science.gov (United States)

    Mcgarry, F.; Esker, L.; Quimby, K.

    1988-01-01

    Many aspects of software development with Ada have evolved as our Ada development environment has matured and personnel have become more experienced in the use of Ada. The Software Engineering Laboratory (SEL) has seen differences in the areas of cost, reliability, reuse, size, and use of Ada features. A first Ada project can be expected to cost about 30 percent more than an equivalent FORTRAN project. However, the SEL has observed significant improvements over time as a development environment progresses to second and third uses of Ada. The reliability of Ada projects is initially similar to what is expected in a mature FORTRAN environment. However, with time, one can expect to gain improvements as experience with the language increases. Reuse is one of the most promising aspects of Ada. The proportion of reusable Ada software on our Ada projects exceeds the proportion of reusable FORTRAN software on our FORTRAN projects. This result was noted fairly early in our Ada projects, and experience shows an increasing trend over time.

  2. Ada education in a software life-cycle context

    Science.gov (United States)

    Clough, Anne J.

    1986-01-01

    Some of the experience gained from a comprehensive educational program undertaken at The Charles Stark Draper Lab. to introduce the Ada language and to transition modern software engineering technology into the development of Ada and non-Ada applications is described. Initially, a core group, which included manager, engineers and programmers, received training in Ada. An Ada Office was established to assume the major responsibility for training, evaluation, acquisition and benchmarking of tools, and consultation on Ada projects. As a first step in this process, and in-house educational program was undertaken to introduce Ada to the Laboratory. Later, a software engineering course was added to the educational program as the need to address issues spanning the entire software life cycle became evident. Educational efforts to date are summarized, with an emphasis on the educational approach adopted. Finally, lessons learned in administering this program are addressed.

  3. Object-oriented programming with mixins in Ada

    Science.gov (United States)

    Seidewitz, ED

    1992-01-01

    Recently, I wrote a paper discussing the lack of 'true' object-oriented programming language features in Ada 83, why one might desire them in Ada, and how they might be added in Ada 9X. The approach I took in this paper was to build the new object-oriented features of Ada 9X as much as possible on the basic constructs and philosophy of Ada 83. The object-oriented features proposed for Ada 9X, while different in detail, are based on the same kind of approach. Further consideration of this approach led me on a long reflection on the nature of object-oriented programming and its application to Ada. The results of this reflection, presented in this paper, show how a fairly natural object-oriented style can indeed be developed even in Ada 83. The exercise of developing this style is useful for at least three reasons: (1) it provides a useful style for programming object-oriented applications in Ada 83 until new features become available with Ada 9X; (2) it demystifies many of the mechanisms that seem to be 'magic' in most object-oriented programming languages by making them explicit; and (3) it points out areas that are and are not in need of change in Ada 83 to make object-oriented programming more natural in Ada 9X. In the next four sections I will address in turn the issues of object-oriented classes, mixins, self-reference and supertyping. The presentation is through a sequence of examples. This results in some overlap with that paper, but all the examples in the present paper are written entirely in Ada 83. I will return to considerations for Ada 9X in the last section of the paper.

  4. The OPEN-ADAS Approach to Atomic Data Provision

    International Nuclear Information System (INIS)

    O'Mullane, M.

    2011-01-01

    Dr O'Mullane of University of Strathclyde presented an overview of the ADAS project (Atomic Data and Analysis Structure, http://www.adas.ac.uk/) and of OPEN-ADAS (http://open.adas.ac.uk/). ADAS is maintained as a self-funding consortium of fusion laboratories. The project provides an interconnected set of computer codes and data collections for modeling the radiating properties of ions and atoms in plasmas. The ADAS data fall into 3 broad classes: 1) Fundamental data such as A- values, cross-sections and effective collision strengths obtained from ADAS collaborators, the literature or data centres. 2) Derived data processed for modeling such as electron temperature and density dependent effective emission coefficients, effective ionization/recombination rates, radiated power and spectral emissivities. 3) Driver data which allow complete regeneration of all ADAS derived data in conjunction with the various ADAS codes. ADAS data uses high quality data as well as baseline data for fall-back when high quality data is not available. The data is mostly embedded in codes and the update without expert help is problematic. The ADAS data formats (adf) are precisely defined and Fortran codes are supplied to read the data sets for easy access. IDL can be used for interactive manipulation. The OPEN-ADAS project is a joint development between the ADAS Project and the IAEA to make the extensive fundamental and derived atomic data for fusion more widely available. It is designed to appeal to both plasma modelers and those interested in the detailed atomic physics. It has been searchable through the Google Scholar and appears in citations, which gives greater visibility and credits to the data producers. The OPEN-ADAS server was replaced due to a series of attacks since June 2011 and was off-line for 8 weeks. The new service removed the registration requirement and hence the user statistics is limited.

  5. QUEST/Ada: Query utility environment for software testing of Ada

    Science.gov (United States)

    Brown, David B.

    1989-01-01

    Results of research and development efforts are presented for Task 1, Phase 2 of a general project entitled, The Development of a Program Analysis Environment for Ada. A prototype of the QUEST/Ada system was developed to collect data to determine the effectiveness of the rule-based testing paradigm. The prototype consists of five parts: the test data generator, the parser/scanner, the test coverage analyzer, a symbolic evaluator, and a data management facility, known as the Librarian. These components are discussed at length. Also presented is an experimental design for the evaluations, an overview of the project, and a schedule for its completion.

  6. ada: An R Package for Stochastic Boosting

    Directory of Open Access Journals (Sweden)

    Mark Culp

    2006-09-01

    Full Text Available Boosting is an iterative algorithm that combines simple classification rules with ‘mediocre’ performance in terms of misclassification error rate to produce a highly accurate classification rule. Stochastic gradient boosting provides an enhancement which incorporates a random mechanism at each boosting step showing an improvement in performance and speed in generating the ensemble. ada is an R package that implements three popular variants of boosting, together with a version of stochastic gradient boosting. In addition, useful plots for data analytic purposes are provided along with an extension to the multi-class case. The algorithms are illustrated with synthetic and real data sets.

  7. ada: An R Package for Stochastic Boosting

    Directory of Open Access Journals (Sweden)

    Mark Culp

    2006-09-01

    Full Text Available Boosting is an iterative algorithm that combines simple classification rules with "mediocre" performance in terms of misclassification error rate to produce a highly accurate classification rule. Stochastic gradient boosting provides an enhancement which incorporates a random mechanism at each boosting step showing an improvement in performance and speed in generating the ensemble. ada is an R package that implements three popular variants of boosting, together with a version of stochastic gradient boosting. In addition, useful plots for data analytic purposes are provided along with an extension to the multi-class case. The algorithms are illustrated with synthetic and real data sets.

  8. Association of G22A and A4223C ADA1 gene polymorphisms and ADA activity with PCOS.

    Science.gov (United States)

    Salehabadi, Mahshid; Farimani, Marzieh; Tavilani, Heidar; Ghorbani, Marzieh; Poormonsefi, Faranak; Poorolajal, Jalal; Shafiei, Gholamreza; Ghasemkhani, Neda; Khodadadi, Iraj

    2016-06-01

    Adenosine deaminase-1 (ADA1) regulates the concentration of adenosine as the main modulator of oocyte maturation. There is compelling evidence for the association of ADA1 gene polymorphisms with many diseases but the importance of ADA1 polymorphisms in polycystic ovary syndrome (PCOS) has not been studied before. This study investigates serum total ADA activity (tADA), ADA1 and ADA2 isoenzyme activities, and genotype and allele frequencies of G22A and A4223C polymorphisms in healthy and PCOS women. In this case-control study 200 PCOS patients and 200 healthy women were enrolled. Genomic DNA was extracted from whole blood and the PCR-RFLP technique was used to determine the G22A and A4223C variants. The genotype frequencies were calculated and the association between polymorphic genotypes and enzyme activities were determined. tADA activity was significantly lower in the PCOS group compared with the control group (27.76±6.0 vs. 39.63±7.48, respectively). PCOS patients also showed reduced activity of ADA1 and ADA2. PCOS was not associated with G22A polymorphism whereas AA, AC, and CC genotypes of A4223C polymorphism were found distributed differently between the control and the PCOS women where the C allele showed a strong protective role for PCOS (odds ratio=1.876, p=0.033). The present study for the first time showed that lower ADA activity may be involved in pathogenesis of PCOS by maintaining a higher concentration of adenosine affecting follicular growth. As a novel finding, we also showed great differences in genotype distribution and allele frequencies of A4223C polymorphism between groups indicating a protective role for C allele against PCOS. AbbreviationsADA: adenosine deaminase PCOS: polycystic ovary syndrome PCR-RFLP: polymerase chain reaction-restriction fragment length polymorphism tADA: total adenosine deaminase.

  9. An Adaptation of the ADA Language for Machine Generated Compilers.

    Science.gov (United States)

    1980-12-01

    Ada Augusta, Lady Lovelace , the daughter of the poet, Lord Byron, and Charles Babbage’s programmer.# 2UNIX is a Trademark/Service Mark of the Bell...productions of the complete Ada language, the somewhat drastic abbreviation mechanism of converting every nonterminal to a two letter sequence was not...AN ADAPTATION OF THE ADA LANGUAGE FOR MACHINE GENERATED COMPILE-ETC(U) JNLSIIO DEC AG M A ROGERS, L P MYERS 7k .A9 22NVLPSTRDASHOOLMONEREYCAF EE9

  10. Developing portable user interfaces for Ada command control software

    OpenAIRE

    Sun, Chien Hsiung

    1990-01-01

    Approved for public release, distribution unlimited DoD mandated use of Ada for embedded systems include Combat and Control System such as shipboard Combat Direction System (CDS). A Low Cost CDS (LCCDS) which will use commercial workstation platforms will require interfacing Ada real-time programs with portable windowing environment such as X Windows. This thesis explores several methods for building X Windows based user interface for Ada C2 programs and provides a step-by-step approach to...

  11. Understanding the Adoption of Ada: A Field Study Report

    Science.gov (United States)

    1989-08-01

    a name change. The name Ada comes from Augusta Ada Byron, Countess of Lovelace , Charles Babbage’s colleague, and according to some, the first computer...Adoption of Ada : * 1 A Field Study Report A Gordon N. Smith Wesley M. Cohen William E. Hefley Daniel A. Levinthal. August 1989 E DTIC *ie jApproved f or...Puib1I release; -A’Djqtribution Unbmtod 0 (3 134 154 Technical Report 0 SEI-88-TR-28 ESD-TR-88-37 August 1989 Understanding the Adoption of Ada : A Field

  12. Ada and its impact on the scientific user

    International Nuclear Information System (INIS)

    Marty, R.

    1982-01-01

    The Ada programming language is the result of a collective effort to design a common language for programming real-time systems. The design of Ada was initiated by the United States Department of Defense (DoD) in 1975. Ada combines facilities found in most classical languages like Fortran, PL/I, Pascal, and Basic together with many features formerly found only in experimental languages. It is argued that these features make Ada a very decent tool not only for writing real-time programs but also for the development of software in the scientific sector. (orig.)

  13. A design for a reusable Ada library

    Science.gov (United States)

    Litke, John D.

    1986-01-01

    A goal of the Ada language standardization effort is to promote reuse of software, implying the existence of substantial software libraries and the storage/retrieval mechanisms to support them. A searching/cataloging mechanism is proposed that permits full or partial distribution of the database, adapts to a variety of searching mechanisms, permits a changine taxonomy with minimal disruption, and minimizes the requirement of specialized cataloger/indexer skills. The important observation is that key words serve not only as indexing mechanism, but also as an identification mechanism, especially via concatenation and as support for a searching mechanism. By deliberately separating these multiple uses, the modifiability and ease of growth that current libraries require, is achieved.

  14. Testing and analysis of DOD Ada language products for NASA

    Science.gov (United States)

    1985-01-01

    An activity is described that is keyed to Johnson Space Center's role as an Ada/APSE test site. Specific objectives and concerns relative to potential utilization of Ada for the Space Station are discussed. Finally, detailed discussion is provided concerning study tasks soon to be contracted out for detailed investigation and project risk assessment.

  15. Fine-Tuning ADAS Algorithm Parameters for Optimizing Traffic ...

    Science.gov (United States)

    With the development of the Connected Vehicle technology that facilitates wirelessly communication among vehicles and road-side infrastructure, the Advanced Driver Assistance Systems (ADAS) can be adopted as an effective tool for accelerating traffic safety and mobility optimization at various highway facilities. To this end, the traffic management centers identify the optimal ADAS algorithm parameter set that enables the maximum improvement of the traffic safety and mobility performance, and broadcast the optimal parameter set wirelessly to individual ADAS-equipped vehicles. After adopting the optimal parameter set, the ADAS-equipped drivers become active agents in the traffic stream that work collectively and consistently to prevent traffic conflicts, lower the intensity of traffic disturbances, and suppress the development of traffic oscillations into heavy traffic jams. Successful implementation of this objective requires the analysis capability of capturing the impact of the ADAS on driving behaviors, and measuring traffic safety and mobility performance under the influence of the ADAS. To address this challenge, this research proposes a synthetic methodology that incorporates the ADAS-affected driving behavior modeling and state-of-the-art microscopic traffic flow modeling into a virtually simulated environment. Building on such an environment, the optimal ADAS algorithm parameter set is identified through an optimization programming framework to enable th

  16. State of the art Advanced Driver Assistance Systems (ADAS).

    NARCIS (Netherlands)

    OEI, H.-L.

    2017-01-01

    An overview of state-of-the-art ADA Advanced Driver Assistance systems is given. First a main structuring system for the ADA systems is presented, needed for purposes of relevancy, and consistency : the three phases in the accident process, i.e. pre-crash, crash and post-crash; the driving task at

  17. Artificial Intelligence in ADA: Pattern-Directed Processing. Final Report.

    Science.gov (United States)

    Reeker, Larry H.; And Others

    To demonstrate to computer programmers that the programming language Ada provides superior facilities for use in artificial intelligence applications, the three papers included in this report investigate the capabilities that exist within Ada for "pattern-directed" programming. The first paper (Larry H. Reeker, Tulane University) is…

  18. 76 FR 38129 - Applications for New Awards; Americans With Disabilities Act (ADA) National Network Knowledge...

    Science.gov (United States)

    2011-06-29

    ... DEPARTMENT OF EDUCATION Applications for New Awards; Americans With Disabilities Act (ADA) National Network Knowledge Translation Center (ADA KT Center) AGENCY: Office of Special Education and... Program--Disability Rehabilitation Research Projects (DRRP)--The ADA National Network Knowledge...

  19. 76 FR 38124 - Applications for New Awards; Americans With Disabilities Act (ADA) National Network Regional...

    Science.gov (United States)

    2011-06-29

    ... DEPARTMENT OF EDUCATION Applications for New Awards; Americans With Disabilities Act (ADA) National Network Regional Centers and ADA National Network Collaborative Research Projects AGENCY: Office... Rehabilitation Research Projects and Centers Program--Disability Rehabilitation Research Projects (DRRP)--ADA...

  20. First International Conference on Ada (R) Programming Language Applications for the NASA Space Station, volume 1

    Science.gov (United States)

    Bown, Rodney L. (Editor)

    1986-01-01

    Topics discussed include: test and verification; environment issues; distributed Ada issues; life cycle issues; Ada in Europe; management/training issues; common Ada interface set; and run time issues.

  1. ADAS: Atomic data, modelling and analysis for fusion

    International Nuclear Information System (INIS)

    Summers, H. P.; O'Mullane, M. G.; Whiteford, A. D.; Badnell, N. R.; Loch, S. D.

    2007-01-01

    The Atomic Data and Analysis Structure, ADAS, comprises extensive fundamental and derived atomic data collections, interactive codes for the manipulation and generation of collisional-radiative data and models, off-line codes for large scale fundamental atomic data production and codes for diagnostic analysis in the fusion and astrophysical environments. ADAS data are organized according to precise specifications, tuned to application and are assigned to numbered ADAS data formats. Some of these formats contain very large quantities of data and some have achieved wide-scale adoption in the fusion community.The paper focuses on recent extensions of ADAS designed to orient ADAS to the needs of ITER. The issue of heavy atomic species, expected to be present as ITER wall and divertor materials, dopants or control species, will be addressed with a view to the economized handling of the emission and ionisation state data needed for diagnostic spectral analysis. Charge exchange and beam emission spectroscopic capabilities and developments in ADAS will be reviewed from an ITER perspective and in the context of a shared analysis between fusion laboratories. Finally an overview and summary of current large scale fundamental data production in the framework of the ADAS project will be given and its intended availability in both fusion and astrophysics noted

  2. Applications of an architecture design and assessment system (ADAS)

    Science.gov (United States)

    Gray, F. Gail; Debrunner, Linda S.; White, Tennis S.

    1988-01-01

    A new Architecture Design and Assessment System (ADAS) tool package is introduced, and a range of possible applications is illustrated. ADAS was used to evaluate the performance of an advanced fault-tolerant computer architecture in a modern flight control application. Bottlenecks were identified and possible solutions suggested. The tool was also used to inject faults into the architecture and evaluate the synchronization algorithm, and improvements are suggested. Finally, ADAS was used as a front end research tool to aid in the design of reconfiguration algorithms in a distributed array architecture.

  3. On 'Money' in ISLM and AD/AS Models

    OpenAIRE

    Thomas K. Rymes; Colin Rogers

    2000-01-01

    Hicks's ISLM model interpretation of Keynes's theory is subject to much controversy. In this paper, we focus upon the 'real balance' effect and its role in ISLM and AD/AS analyses. We shall argue that ISLM and AD/AS require 'nominal anchors'. We live in a world where, increasingly, the 'money' in the ISLM and AD/AS model no longer exists (as Keynes imperfectly understood in his TREATISE ON MONEy). There are no longer any nominal anchors, rather they have been replaced by discretionary policy....

  4. Integrity and security in an Ada runtime environment

    Science.gov (United States)

    Bown, Rodney L.

    1991-01-01

    A review is provided of the Formal Methods group discussions. It was stated that integrity is not a pure mathematical dual of security. The input data is part of the integrity domain. The group provided a roadmap for research. One item of the roadmap and the final position statement are closely related to the space shuttle and space station. The group's position is to use a safe subset of Ada. Examples of safe sets include the Army Secure Operating System and the Penelope Ada verification tool. It is recommended that a conservative attitude is required when writing Ada code for life and property critical systems.

  5. Bahan pemutih gigi dengan sertifikat ADA/ISO (Tooth bleaching material with ADA/ISO certificate

    Directory of Open Access Journals (Sweden)

    Asti Meizarini

    2005-06-01

    Full Text Available Bleaching of teeth for cosmetic reasons is a popular aspect of cosmetic dentistry because patients realize the aesthetical benefits of these products. The dentist as a clinician's practitioner must be knowledgeable of the products and their application techniques. Bleaching materials which are safe and effective are the ADA accepted or manufactured by those which have already haved ISO certificate. Dentist must have enough knowledge about in-office bleaching prescribed for home-use bleaching including their contra indication and side effects, to advise the patients and provide effective bleaching services.

  6. QUEST/Ada (Query Utility Environment for Software Testing of Ada): The development of a prgram analysis environment for Ada, task 1, phase 2

    Science.gov (United States)

    Brown, David B.

    1990-01-01

    The results of research and development efforts are described for Task one, Phase two of a general project entitled The Development of a Program Analysis Environment for Ada. The scope of this task includes the design and development of a prototype system for testing Ada software modules at the unit level. The system is called Query Utility Environment for Software Testing of Ada (QUEST/Ada). The prototype for condition coverage provides a platform that implements expert system interaction with program testing. The expert system can modify data in the instrument source code in order to achieve coverage goals. Given this initial prototype, it is possible to evaluate the rule base in order to develop improved rules for test case generation. The goals of Phase two are the following: (1) to continue to develop and improve the current user interface to support the other goals of this research effort (i.e., those related to improved testing efficiency and increased code reliable); (2) to develop and empirically evaluate a succession of alternative rule bases for the test case generator such that the expert system achieves coverage in a more efficient manner; and (3) to extend the concepts of the current test environment to address the issues of Ada concurrency.

  7. On some key features of Ada : Language and programming environment

    Science.gov (United States)

    Wehrum, R. P.; Hoyer, W.; Dießl, G.

    1986-08-01

    The present paper focuses upon those aspects of the Ada language whose purpose is to support the discipline of software engineering. It illustrates the use of Ada features for various forms of abstraction, separate compilation, exception handling and tasking and highlights the importance of separating the definition of a module interface from its implementation. It demonstrates the use of the package concept to realize information hiding, data encapsulation and abstract data types. Some key aspects of Ada numerics are dealt with briefly. The paper continues by providing an overview of the Ada programming environments, their history and their relationship to the CAIS interface. Finally, the special importance of the interactive debugger within such an environment is presented.

  8. Latvian PR people are world class / Ada Parr

    Index Scriptorium Estoniae

    Parr, Ada

    2004-01-01

    Suhtekorraldusfirma Porter Novelli rahvusvahelise partnerluse juht suhtekorralduse osatähtsuse kasvust ettevõtete äritegevuses, suhtekorraldusturu olukorrast ja teenuste kvaliteedi tasemest Baltimaades. Vt. samas: Ada Parr recommends

  9. A report on NASA software engineering and Ada training requirements

    Science.gov (United States)

    Legrand, Sue; Freedman, Glenn B.; Svabek, L.

    1987-01-01

    NASA's software engineering and Ada skill base are assessed and information that may result in new models for software engineering, Ada training plans, and curricula are provided. A quantitative assessment which reflects the requirements for software engineering and Ada training across NASA is provided. A recommended implementation plan including a suggested curriculum with associated duration per course and suggested means of delivery is also provided. The distinction between education and training is made. Although it was directed to focus on NASA's need for the latter, the key relationships to software engineering education are also identified. A rationale and strategy for implementing a life cycle education and training program are detailed in support of improved software engineering practices and the transition to Ada.

  10. Adenosine-deaminase (ADA activity in Psoriasis (A Preliminary Study

    Directory of Open Access Journals (Sweden)

    S D Chaudhry

    1988-01-01

    Full Text Available Study of adenosine-deaminase activity ′in 23 patients hav-mg psoriasis compared with an equal number of healthy controls revealed significantly high ADA-activity in the psotiatic patients.

  11. On the Suitability of ADA for Artificial Intelligence Applications

    Science.gov (United States)

    1980-07-01

    ON THE SUITABILITY OF ADA FOR ARTIFICIAL INTELLIGENCE APPLICATIONS July 1980 0By: Richard L. Schwartz P. M. Melliar-Smith Project Scientists Computer... ARTIFICIAL INTELLIGENCE APPLICATIONS July 1980 By: Richard L. Schwartz, Computer Scientist P. M. Melliar-Smith, Senior Computer Scientist Computer Science...Research The following papers have been prepared during this project: 0"The Suitability of Ada for Artificial Intelligence Applications ". Final

  12. An Ada environment for relativistic cross section calculations

    International Nuclear Information System (INIS)

    Nilsson, E.

    1990-01-01

    We have developed an Ada environment adapted to relativistic cross section calculations. Objects such as four-vectors, γ- matrices and propagators are defined as well as operations between these objects. In this environment matrix elements can be expressed in a compact and readable way as Ada code. Unpolarized cross sections are calculated numerically by explicitly summing and averaging over spins and polarizations. A short presentation of the technique is given

  13. An Independent Evaluation of the Declarative ADA Dialect

    Science.gov (United States)

    1994-01-01

    implementation. We believe it would have been better to have written the DAD language definition to say that a full implementation requires garbage...particular, both nested first class function definitions and exception handlers am translated into Ada code that does not compile correctly. In...pursue alternative approaches such as providing support for interlanguage calls between Ada and Smalltalk, ML or Miranda. The DAD software delivered by the

  14. Compiling knowledge-based systems from KEE to Ada

    Science.gov (United States)

    Filman, Robert E.; Bock, Conrad; Feldman, Roy

    1990-01-01

    The dominant technology for developing AI applications is to work in a multi-mechanism, integrated, knowledge-based system (KBS) development environment. Unfortunately, systems developed in such environments are inappropriate for delivering many applications - most importantly, they carry the baggage of the entire Lisp environment and are not written in conventional languages. One resolution of this problem would be to compile applications from complex environments to conventional languages. Here the first efforts to develop a system for compiling KBS developed in KEE to Ada (trademark). This system is called KATYDID, for KEE/Ada Translation Yields Development Into Delivery. KATYDID includes early prototypes of a run-time KEE core (object-structure) library module for Ada, and translation mechanisms for knowledge structures, rules, and Lisp code to Ada. Using these tools, part of a simple expert system was compiled (not quite automatically) to run in a purely Ada environment. This experience has given us various insights on Ada as an artificial intelligence programming language, potential solutions of some of the engineering difficulties encountered in early work, and inspiration on future system development.

  15. Examining the reliability of ADAS-Cog change scores.

    Science.gov (United States)

    Grochowalski, Joseph H; Liu, Ying; Siedlecki, Karen L

    2016-09-01

    The purpose of this study was to estimate and examine ways to improve the reliability of change scores on the Alzheimer's Disease Assessment Scale, Cognitive Subtest (ADAS-Cog). The sample, provided by the Alzheimer's Disease Neuroimaging Initiative, included individuals with Alzheimer's disease (AD) (n = 153) and individuals with mild cognitive impairment (MCI) (n = 352). All participants were administered the ADAS-Cog at baseline and 1 year, and change scores were calculated as the difference in scores over the 1-year period. Three types of change score reliabilities were estimated using multivariate generalizability. Two methods to increase change score reliability were evaluated: reweighting the subtests of the scale and adding more subtests. Reliability of ADAS-Cog change scores over 1 year was low for both the AD sample (ranging from .53 to .64) and the MCI sample (.39 to .61). Reweighting the change scores from the AD sample improved reliability (.68 to .76), but lengthening provided no useful improvement for either sample. The MCI change scores had low reliability, even with reweighting and adding additional subtests. The ADAS-Cog scores had low reliability for measuring change. Researchers using the ADAS-Cog should estimate and report reliability for their use of the change scores. The ADAS-Cog change scores are not recommended for assessment of meaningful clinical change.

  16. STUDY OF BCG SCAR AND SERUM ADA LEVELS IN INFANTS

    Directory of Open Access Journals (Sweden)

    Harishchandra Venkata Yanamandala

    2017-11-01

    Full Text Available BACKGROUND In developing countries, in both adults and children, tuberculosis is an important cause of morbidity and mortality. In 1993, it is declared as the first infectious disease by global health emergency.1 According to WHO report globally, there were an estimated 9.27 million ancient cases of TB in 2009. The cases reported were 8.3 million, the children covered an estimated percentage of 11 and it ranged from 3-25 percent.2 BCG vaccination was advocated for prevention of tuberculosis in children. The aim of the study is to estimate serum ADA levels in newborns before BCG vaccination, serum ADA levels in children with and without BCG scar, after receiving BCG vaccination, serum ADA levels in children without BCG vaccination and to find significance of serum ADA levels in BCG vaccinated children by comparing the above groups. MATERIALS AND METHODS This study was conducted at the Department of Paediatrics, Gitam Institute of Medical Sciences and Research Institute, October 2015 to September 2016. Babies who were in postnatal ward and infants of age of 12 weeks attending for BCG vaccination were included in the study. The total numbers of infants studied were 150. RESULTS In our study, out of 120 children included in the study before BCG vaccination comprising group-1, 61% were males and 39% were females. Out of 120 children received BCG vaccination, only 100 came for follow up comprising group-2, of which 67 (67% were males and 33 (33% were females. 15 children who did not receive BCG vaccination at 12 weeks of age were included in group 3 out of which 11 (73.33% were males and 4 (26.67% were females. Mean ADA levels at the age of 12 weeks in group-2 who were vaccinated at birth were 30.89 ± 5.27 U/L compared to mean ADA levels at the age of 12 weeks in group-3, which was 15.47 ± 1.85 U/L. This shows significant rise in mean ADA levels at 12 weeks of age in those who were vaccinated at birth comprising group-2 compared to their mean ADA

  17. Two Arabidopsis orthologs of the transcriptional coactivator ADA2 have distinct biological functions.

    Science.gov (United States)

    Hark, Amy T; Vlachonasios, Konstantinos E; Pavangadkar, Kanchan A; Rao, Sumana; Gordon, Hillary; Adamakis, Ioannis-Dimosthenis; Kaldis, Athanasios; Thomashow, Michael F; Triezenberg, Steven J

    2009-02-01

    Histone acetylation is an example of covalent modification of chromatin structure that has the potential to regulate gene expression. Gcn5 is a prototypical histone acetyltransferase that associates with the transcriptional coactivator Ada2. In Arabidopsis, two genes encode proteins that resemble yeast ADA2 and share approximately 45% amino acid sequence identity. We previously reported that plants harboring a T-DNA insertion in the ADA2b gene display a dwarf phenotype with developmental defects in several organs. Here we describe T-DNA insertion alleles in the ADA2a gene, which result in no dramatic growth or developmental phenotype. Both ADA2a and ADA2b are expressed in a variety of plant tissues; moreover, expression of ADA2a from a constitutive promoter fails to complement the ada2b-1 mutant phenotype, consistent with the hypothesis that the two proteins have distinct biochemical roles. To further probe the cellular roles of ADA2a and ADA2b, we studied the response of the transcriptional coactivator mutants to abiotic stress. Although ada2b seedlings display hypersensitivity to salt and abscisic acid and altered responses to low temperature stress, the responses of ada2a seedlings to abiotic stress generally parallel those of wildtype plants. Intriguingly, ada2a;ada2b double mutant plants display an intermediate, gcn5-like phenotype, suggesting that ADA2a and ADA2b each work independently with GCN5 to affect genome function in Arabidopsis.

  18. The Synergy Between PAV and AdaBoost.

    Science.gov (United States)

    Wilbur, W John; Yeganova, Lana; Kim, Won

    2005-11-01

    Schapire and Singer's improved version of AdaBoost for handling weak hypotheses with confidence rated predictions represents an important advance in the theory and practice of boosting. Its success results from a more efficient use of information in weak hypotheses during updating. Instead of simple binary voting a weak hypothesis is allowed to vote for or against a classification with a variable strength or confidence. The Pool Adjacent Violators (PAV) algorithm is a method for converting a score into a probability. We show how PAV may be applied to a weak hypothesis to yield a new weak hypothesis which is in a sense an ideal confidence rated prediction and that this leads to an optimal updating for AdaBoost. The result is a new algorithm which we term PAV-AdaBoost. We give several examples illustrating problems for which this new algorithm provides advantages in performance.

  19. V Olimpíada Brasileira de Astronomia

    Science.gov (United States)

    Villas da Rocha, J. F.; Canalle, J. B. G.; Wuesnche, C. A.; de Medeiros, J. R., Silva, A. V. R.; Lavouras, D. F.; Dottori, H. A.; Maia, M. A. G.; Vieira Martins, R.; Poppe, P. C. R.

    2003-08-01

    Neste trabalho apresentamos os resultados da V Olimpíada Brasileira de Astronomia, a qual ocorreu em 11/05/2002 em todos os estabelecimentos de ensino fundamental ou médio previamente cadastrados. Participaram do evento 60.338 alunos distribuídos por 1469 escolas pertencentes a todos os Estados brasileiros. Uma equipe de 5 alunos foi escolhida para representar o Brasil na VII Olimpíada Internacional de Astronomia que ocorreu na Rússia em 2002 e dois de nossos alunos ganharam a medalha de bronze naquele evento.

  20. DNA repair by the Ada protein of E. coli

    International Nuclear Information System (INIS)

    Karran, P.; Hall, J.

    1988-01-01

    This paper discusses the Ada protein of E. coli which exemplifies the highly specialized nature of the enzymes which have evolved to repair DNA. According to the authors, this protein exhibits not only novel mechanistic features but also provides an apparently unique example of a strategy for controlling gene expression in E. coli. They report that knowledge of the properties and mode of action of the Ada protein has afforded insight into how human cells are affected by alkylating agents, including those used in chemotherapy

  1. Impact of Ada in the Flight Dynamics Division: Excitement and frustration

    Science.gov (United States)

    Bailey, John; Waligora, Sharon; Stark, Mike

    1993-01-01

    In 1985, NASA Goddard's Flight Dynamics Division (FDD) began investigating how the Ada language might apply to their software development projects. Although they began cautiously using Ada on only a few pilot projects, they expected that, if the Ada pilots showed promising results, they would fully transition their entire development organization from FORTRAN to Ada within 10 years. However, nearly 9 years later, the FDD still produces 80 percent of its software in FORTRAN, despite positive results on Ada projects. This paper reports preliminary results of an ongoing study, commissioned by the FDD, to quantify the impact of Ada in the FDD, to determine why Ada has not flourished, and to recommend future directions regarding Ada. Project trends in both languages are examined as are external factors and cultural issues that affected the infusion of this technology. This paper is the first public report on the Ada assessment study, which will conclude with a comprehensive final report in mid 1994.

  2. Understanding road users’ expectations : an essential step for ADAS development.

    NARCIS (Netherlands)

    Houtenbos, M. Jagtman, H.M. Hagenzieker, M.P. Wieringa, P.A. & Hale, A.R.

    2006-01-01

    This article indicates the need for understanding road users’ expectations when developing Advanced Driver Assistance Systems (ADAS). Nowadays, technology allows more and more opportunities to provide road users with all sorts of information or even actively support aspects of the driving task.

  3. Older drivers and ADAS : which systems improve road safety?

    NARCIS (Netherlands)

    Davidse, R.J.

    2006-01-01

    In the coming decades, the number of older drivers that experiences difficulties in traffic as a result of functional limitations will strongly increase. Advanced Driver Assistance Systems (ADAS) could resolve some of these difficulties, by providing personal assistance in a road environment that

  4. Techniques and implementation of the embedded rule-based expert system using Ada

    Science.gov (United States)

    Liberman, Eugene M.; Jones, Robert E.

    1991-01-01

    Ada is becoming an increasingly popular programming language for large Government-funded software projects. Ada with its portability, transportability, and maintainability lends itself well to today's complex programming environment. In addition, expert systems have also assured a growing role in providing human-like reasoning capability and expertise for computer systems. The integration of expert system technology with Ada programming language, specifically a rule-based expert system using an ART-Ada (Automated Reasoning Tool for Ada) system shell is discussed. The NASA Lewis Research Center was chosen as a beta test site for ART-Ada. The test was conducted by implementing the existing Autonomous Power EXpert System (APEX), a Lisp-base power expert system, in ART-Ada. Three components, the rule-based expert system, a graphics user interface, and communications software make up SMART-Ada (Systems fault Management with ART-Ada). The main objective, to conduct a beta test on the ART-Ada rule-based expert system shell, was achieved. The system is operational. New Ada tools will assist in future successful projects. ART-Ada is one such tool and is a viable alternative to the straight Ada code when an application requires a rule-based or knowledge-based approach.

  5. An Assessment of Ada’s Suitability in General Purpose Programming Applications.

    Science.gov (United States)

    1985-09-01

    selected to honor the mathematician Lady Augusta Ada Byron (1815-1852), Countess of Lovelace . The Countess worked with Charles Babbage on his difference...stray from our research objectives. We would also like to thank Dr. Charles Richard for the assistance he gave us while learning the Ada language...7 introduction. . . . . . . . . . . . . . . . . 7 3ackground: General Issue. 7 Ada Development . . . . . . . . ... . . . . . . 11

  6. 77 FR 36231 - Americans With Disabilities Act (ADA) and Architectural Barriers Act (ABA) Accessibility...

    Science.gov (United States)

    2012-06-18

    ...-0004] RIN 3014-AA39 Americans With Disabilities Act (ADA) and Architectural Barriers Act (ABA... (ADA) and Architectural Barriers Act (ABA) Accessibility Guidelines to specifically address emergency... ensure that newly constructed and altered emergency transportable housing units covered by the ADA or ABA...

  7. 78 FR 10263 - Proposed Collection; Comment Request for ADA Accommodations Request Packet

    Science.gov (United States)

    2013-02-13

    ... DEPARTMENT OF THE TREASURY Internal Revenue Service Proposed Collection; Comment Request for ADA... the ADA Accommodations Packet. DATES: Written comments should be received on or before April 15, 2013...: ADA Accommodations Request Packet. OMB Number: 1545-2027. Abstract: Information is collected so that...

  8. Development of the Korean version of Alzheimer's Disease Assessment Scale (ADAS-K).

    Science.gov (United States)

    Youn, J C; Lee, D Y; Kim, K W; Lee, J H; Jhoo, J H; Lee, K U; Ha, J; Woo, J I

    2002-09-01

    The purpose of this study was the development of the Korean Version of Alzheimer's Disease Assessment Scale (ADAS-K). ADAS-K was administrated to 84 AD patients as well as 105 non-demented control subjects. Three aspects of reliability were tested. To evaluate the validity of ADAS-K, discriminant validity and concurrent validity were tested. To evaluate the sensitivity of ADAS-K to disease severity, all subjects, AD patients and control subjects, were grouped by CDR scale and their mean scores on ADAS-K were compared. ADAS-K demonstrated high levels of reliability. Mean ADAS-K scores for AD patients were significantly different from the control group (p ADAS-K exhibited significant correlations with other tests and scales (range 0.45-0.85, p ADAS-K displayed high diagnostic efficacy and the optimal cut-off point was selected between 18/19. ADAS-K was able to discriminate the degree of AD severity according to CDR classification. Our results suggested that ADAS-K-cog was sensitive to very mild AD. We demonstrated that ADAS-K is a reliable and valid instrument not only for AD diagnosis but also for evaluation of its severity. Copyright 2002 John Wiley & Sons, Ltd.

  9. 76 FR 31892 - Recordkeeping and Reporting Requirements Under Title VII, the ADA, and GINA

    Science.gov (United States)

    2011-06-02

    ... Requirements Under Title VII, the ADA, and GINA AGENCY: Equal Employment Opportunity Commission. ACTION: Notice... Civil Rights Act of 1964 (Title VII) and the Americans with Disabilities Act (ADA) to entities covered... the same record retention requirements under GINA that are imposed under Title VII and the ADA, i.e...

  10. 75 FR 43747 - Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles

    Science.gov (United States)

    2010-07-26

    ... With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles; Proposed Rule #0;#0... 3014-AA38 Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles... Disabilities Act (ADA) prohibits discrimination on the basis of disability in the provision of transportation...

  11. 76 FR 79065 - Recordkeeping and Reporting Requirements Under Title VII, the ADA and GINA

    Science.gov (United States)

    2011-12-21

    ... Reporting Requirements Under Title VII, the ADA and GINA CFR Correction In Title 29 of the Code of Federal... title VII or section 107 of the ADA'' and add in their place the words ``section 709(c) of title VII, section 107 of the ADA, or section 207(a) of GINA'' wherever they appear in the following sections...

  12. 77 FR 5396 - Recordkeeping and Reporting Requirements Under Title VII, the ADA, and GINA

    Science.gov (United States)

    2012-02-03

    ... Requirements Under Title VII, the ADA, and GINA AGENCY: Equal Employment Opportunity Commission. ACTION: Final... (Title VII) and the Americans with Disabilities Act (ADA) to entities covered by title II of the Genetic... requirements under GINA that apply under Title VII and the ADA, i.e., any records made or kept must be retained...

  13. 78 FR 34095 - Adequacy Status of the Idaho, Northern Ada County PM10

    Science.gov (United States)

    2013-06-06

    ..., Northern Ada County PM 10 State Implementation Plan for Transportation Conformity Purposes AGENCY...), and volatile organic compounds (VOC) for the years 2008, 2015 and 2023 in the Northern Ada County PM... Northern Ada County. The EPA's finding was made pursuant to the adequacy review process for implementation...

  14. Development of Software Tools for ADA Compliance Data Collection, Management, and Inquiry

    Science.gov (United States)

    2014-07-01

    In this NUTC research project, the UNR research team developed an iOS application (named NDOT ADA Data) to efficiently and intuitively collect ADA inventory data with iPhones or iPads. This tool was developed to facilitate NDOT ADA data collect...

  15. Evolution of Ada technology in the flight dynamics area: Implementation/testing phase analysis

    Science.gov (United States)

    Quimby, Kelvin L.; Esker, Linda; Miller, John; Smith, Laurie; Stark, Mike; Mcgarry, Frank

    1989-01-01

    An analysis is presented of the software engineering issues related to the use of Ada for the implementation and system testing phases of four Ada projects developed in the flight dynamics area. These projects reflect an evolving understanding of more effective use of Ada features. In addition, the testing methodology used on these projects has changed substantially from that used on previous FORTRAN projects.

  16. Administration and scoring variance on the ADAS-Cog.

    Science.gov (United States)

    Connor, Donald J; Sabbagh, Marwan N

    2008-11-01

    The Alzheimer's Disease Assessment Scale - Cognitive (ADAS-Cog) is the most commonly used primary outcome instrument in clinical trials for treatments of dementia. Variations in forms, administration procedures and scoring rules, along with rater turnover and intra-rater drift may decrease the reliability of the instrument. A survey of possible variations in the ADAS-Cog was administered to 26 volunteer raters at a clinical trials meeting. Results indicate notable protocol variations in the forms used, administration procedures, and scoring rules. Since change over time is used to determine treatment effect in clinical trials, standardizing the instrument's ambiguities and addressing common problems will greatly increase the instrument's reliability and thereby enhance its sensitivity to treatment effects.

  17. Uma maquina virtual para ADA num sistema com multiplos processadores

    OpenAIRE

    Osvaldo Alves dos Santos

    1985-01-01

    Resumo: A linguagem de programação Ada é uma linguagem de propósito geral, possuindo os recursos oferecidos pelas linguagens clássicas tais como Pascal e Algol bem como as facilidades de elaboração de programas modulares. Programação de sistemas e programação em tempo real, que normalmente são encontradas somente em linguagens específicas. Neste texto é apresentada uma proposta de um sistema de execução para Ada. Dada a extensão do trabalho, será tratada somente a parte concorrente e as exceç...

  18. AN ADA LINEAR ALGEBRA PACKAGE MODELED AFTER HAL/S

    Science.gov (United States)

    Klumpp, A. R.

    1994-01-01

    This package extends the Ada programming language to include linear algebra capabilities similar to those of the HAL/S programming language. The package is designed for avionics applications such as Space Station flight software. In addition to the HAL/S built-in functions, the package incorporates the quaternion functions used in the Shuttle and Galileo projects, and routines from LINPAK that solve systems of equations involving general square matrices. Language conventions in this package follow those of HAL/S to the maximum extent practical and minimize the effort required for writing new avionics software and translating existent software into Ada. Valid numeric types in this package include scalar, vector, matrix, and quaternion declarations. (Quaternions are fourcomponent vectors used in representing motion between two coordinate frames). Single precision and double precision floating point arithmetic is available in addition to the standard double precision integer manipulation. Infix operators are used instead of function calls to define dot products, cross products, quaternion products, and mixed scalar-vector, scalar-matrix, and vector-matrix products. The package contains two generic programs: one for floating point, and one for integer. The actual component type is passed as a formal parameter to the generic linear algebra package. The procedures for solving systems of linear equations defined by general matrices include GEFA, GECO, GESL, and GIDI. The HAL/S functions include ABVAL, UNIT, TRACE, DET, INVERSE, TRANSPOSE, GET, PUT, FETCH, PLACE, and IDENTITY. This package is written in Ada (Version 1.2) for batch execution and is machine independent. The linear algebra software depends on nothing outside the Ada language except for a call to a square root function for floating point scalars (such as SQRT in the DEC VAX MATHLIB library). This program was developed in 1989, and is a copyrighted work with all copyright vested in NASA.

  19. Ada Quality and Style: Guidelines for Professional Programmers

    Science.gov (United States)

    1989-01-01

    the older report. blank, the abstract is assumed to L Bc unlimited. Standard Form 298 Back (Rev. 2-89) 4~~~ SOFWARE .PRODUCTIVITY .. CONSORTIUM Ada...tasking implementation, or a reorganization of services among tasks need not concern users of the package. This guideline supports information hiding...inversion, where lower priority tasks are given service while higher priority tasks remain blocked. A program like the one in the example might behave

  20. Olimpíadas e geopolítica

    Directory of Open Access Journals (Sweden)

    João Fábio Bertonha

    2008-09-01

    Full Text Available

    o artigo trata de competições esportivas,

    em especial as olimpíadas. Nelas, valorizam-se o

    nacionalismo e o poder dos países.

  1. Issues and Approaches in the Design of Distributed Ada Programs.

    Science.gov (United States)

    1989-10-11

    COVERED 11 October 1989 jFinal ____________ 4- ILE AND SUBTITLE . FUID "N NUMES Issues and Approaches in the Design of Distributed Ada PR E45146 Programs...connections between end systems and provides end-to-end flow control and error control. The transport layer was designed according to the ISO standards...34out-of-band" data transfer, bypassing the flow control mechanisms of the transport layer. Message control types were included in the kernel to

  2. Software tools to aid Pascal and Ada program design

    Energy Technology Data Exchange (ETDEWEB)

    Jankowitz, H.T.

    1987-01-01

    This thesis describes a software tool which analyses the style and structure of Pascal and Ada programs by ensuring that some minimum design requirements are fulfilled. The tool is used in much the same way as a compiler is used to teach students the syntax of a language, only in this case issues related to the design and structure of the program are of paramount importance. The tool operates by analyzing the design and structure of a syntactically correct program, automatically generating a report detailing changes that need to be made in order to ensure that the program is structurally sound. The author discusses how the model gradually evolved from a plagiarism detection system which extracted several measurable characteristics in a program to a model that analyzed the style of Pascal programs. In order to incorporate more-sophistical concepts like data abstraction, information hiding and data protection, this model was then extended to analyze the composition of Ada programs. The Ada model takes full advantage of facilities offered in the language and by using this tool the standard and quality of written programs is raised whilst the fundamental principles of program design are grasped through a process of self-tuition.

  3. Overfitting Reduction of Text Classification Based on AdaBELM

    Directory of Open Access Journals (Sweden)

    Xiaoyue Feng

    2017-07-01

    Full Text Available Overfitting is an important problem in machine learning. Several algorithms, such as the extreme learning machine (ELM, suffer from this issue when facing high-dimensional sparse data, e.g., in text classification. One common issue is that the extent of overfitting is not well quantified. In this paper, we propose a quantitative measure of overfitting referred to as the rate of overfitting (RO and a novel model, named AdaBELM, to reduce the overfitting. With RO, the overfitting problem can be quantitatively measured and identified. The newly proposed model can achieve high performance on multi-class text classification. To evaluate the generalizability of the new model, we designed experiments based on three datasets, i.e., the 20 Newsgroups, Reuters-21578, and BioMed corpora, which represent balanced, unbalanced, and real application data, respectively. Experiment results demonstrate that AdaBELM can reduce overfitting and outperform classical ELM, decision tree, random forests, and AdaBoost on all three text-classification datasets; for example, it can achieve 62.2% higher accuracy than ELM. Therefore, the proposed model has a good generalizability.

  4. Chagas Parasite Detection in Blood Images Using AdaBoost

    Directory of Open Access Journals (Sweden)

    Víctor Uc-Cetina

    2015-01-01

    Full Text Available The Chagas disease is a potentially life-threatening illness caused by the protozoan parasite, Trypanosoma cruzi. Visual detection of such parasite through microscopic inspection is a tedious and time-consuming task. In this paper, we provide an AdaBoost learning solution to the task of Chagas parasite detection in blood images. We give details of the algorithm and our experimental setup. With this method, we get 100% and 93.25% of sensitivity and specificity, respectively. A ROC comparison with the method most commonly used for the detection of malaria parasites based on support vector machines (SVM is also provided. Our experimental work shows mainly two things: (1 Chagas parasites can be detected automatically using machine learning methods with high accuracy and (2 AdaBoost + SVM provides better overall detection performance than AdaBoost or SVMs alone. Such results are the best ones known so far for the problem of automatic detection of Chagas parasites through the use of machine learning, computer vision, and image processing methods.

  5. Ada Compiler Validation Summary Report: Certificate Number: 920509S1. 11259 Alenia Aeritalia and Selenia S.p.A DACS VAX/VMS to 80x86 PM MARA Ada Cross Compiler, Version 4.6 Microvax 4000/200 = MARA

    Science.gov (United States)

    1992-01-01

    handling associated to any process which implements an ADA task. It is activated whenever there is an exception, whether it is Ada or is not Ada. codice ...INTERFACE exc. non ADA ------- v codice ADA exception ADA AH A AI .1 I sistema operativo exc. non ADA ------- - fig. 1- Function Exception Handling is

  6. An Overview of Advanced Data Acquisition System (ADAS)

    Science.gov (United States)

    Mata, Carlos T.; Steinrock, T. (Technical Monitor)

    2001-01-01

    The paper discusses the following: 1. Historical background. 2. What is ADAS? 3. R and D status. 4. Reliability/cost examples (1, 2, and 3). 5. What's new? 6. Technical advantages. 7. NASA relevance. 8. NASA plans/options. 9. Remaining R and D. 10. Applications. 11. Product benefits. 11. Commercial advantages. 12. intellectual property. Aerospace industry requires highly reliable data acquisition systems. Traditional Acquisition systems employ end-to-end hardware and software redundancy. Typically, redundancy adds weight, cost, power consumption, and complexity.

  7. Large distributed control system using ADA in fusion research

    Energy Technology Data Exchange (ETDEWEB)

    Woodruff, J. P., LLNL

    1998-04-21

    Construction of the National Ignition Facility laser at Lawrence Livermore National Laboratory features a large distributed control system constructed using object-oriented software engineering techniques. Control of 60,000 devices is effected using a network of some 500 computers that run software written in Ada and communicating through CORBA. The project has completed its final design review; implementation of the first of five planned increments will be delivered at the end of fiscal year 1998. Preliminary measures of the distributed controls performance confirm the design decisions reported in this paper, and the measurement and supporting simulation of full system performance continue.

  8. How the FDA and the ADA affect development of prescription drugs for oral care.

    Science.gov (United States)

    Cooley, W E

    1992-01-01

    The patient-consumer, the health professional, and the producer are all essential in the world of prescription drugs for oral care. Also essential are the Food and Drug Administration (FDA) and the American Dental Association (ADA). The FDA is charged with reviewing new-drug applications in the United States and approving those drugs that are proved safe and effective. The FDA also controls prescription-drug advertising and promotion. The ADA applies professional standards in judging all submitted dental drugs. Those drugs accepted by ADA's Council on Dental Therapeutics may display the ADA seal in labeling and advertising. All advertising for accepted products must be cleared by the ADA. An example of a prescription drug approved by the FDA and accepted by the ADA is 0.12 percent chlorhexidine gluconate oral rinse (Peridex). This drug followed the FDA's investigational-drug (IND) regulations before final approval as a treatment for gingivitis.

  9. Rethinking ADA signage standards for low-vision accessibility

    Science.gov (United States)

    Arditi, Aries

    2017-01-01

    Americans With Disabilities Act (ADA) and International Code Council (ICC) standards for accessible buildings and facilities affect design and construction of all new and renovated buildings throughout the United States, and form the basis for compliance with the ADA. While these standards may result in acceptable accessibility for people who are fully blind, they fall far short of what they could and should accomplish for those with low vision. In this article I critique the standards, detailing their lack of evidence base and other shortcomings. I suggest that simply making existing requirements stricter (e.g., by mandating larger letter size or higher contrasts) will not ensure visual accessibility and therefore cannot act as a valid basis for compliance with the law. I propose two remedies. First, requirements for visual characteristics of signs intended to improve access for those with low vision should be expressed not in terms of physical features, such as character height and contrast, but rather in terms of the distance at which a sign can be read by someone with nominally normal (20/20) visual acuity under expected lighting conditions for the installed environment. This would give sign designers greater choice in design parameters but place on them the burden of ensuring legibility. Second, mounting of directional signs, which are critical for effective and efficient wayfinding, should be required to be in consistent and approachable locations so that those with reduced acuity may view them at close distance. PMID:28510625

  10. Space station Ada runtime support for nested atomic transactions

    Science.gov (United States)

    Monteiro, Edward J.

    1986-01-01

    The Space Station Data Management System (DMS), associated computing subsystems, and applications have varying degrees of reliability associated with their operation. A model has been developed (McKay '86) which allows the DMS runtime environment to appear as an Ada virtual machine to applications executing within it. This model is modular, flexible, and dynamically configurable to allow for evolution and growth over time. Support for Fault-tolerant computing is included within this model. The basic primitive involved in this support is based on atomic actions (Grey '78). An atomic action possesses two fundamental properties: (1) it is indivisible with respect to concurrent actions, and (2) it is indivisible with respect to failure. A transaction is a collection of atomic actions which collectively appear to be one action. Transactions may be nested, providing even more powerful support for reliability. A proposed approach is described for providing support for nested atomic transactions within the Ada runtime model developed for the Space Station environment. The level of support is modular, flexible and dynamically configurable just like the overall runtime support environment.

  11. Efficient Ada multitasking on a RISC register window architecture

    Science.gov (United States)

    Kearns, J. P.; Quammen, D.

    1987-01-01

    This work addresses the problem of reducing context switch overhead on a processor which supports a large register file - a register file much like that which is part of the Berkeley RISC processors and several other emerging architectures (which are not necessarily reduced instruction set machines in the purest sense). Such a reduction in overhead is particularly desirable in a real-time embedded application, in which task-to-task context switch overhead may result in failure to meet crucial deadlines. A storage management technique by which a context switch may be implemented as cheaply as a procedure call is presented. The essence of this technique is the avoidance of the save/restore of registers on the context switch. This is achieved through analysis of the static source text of an Ada tasking program. Information gained during that analysis directs the optimized storage management strategy for that program at run time. A formal verification of the technique in terms of an operational control model and an evaluation of the technique's performance via simulations driven by synthetic Ada program traces are presented.

  12. TCP-ADaLR: TCP with adaptive delay and loss response for broadband GEO satellite networks

    OpenAIRE

    Omueti, Modupe Omogbohun

    2007-01-01

    Transmission Control Protocol (TCP) performance degrades in broadband geostationary satellite networks due to long propagation delays and high bit error rates. In this thesis, we propose TCP with algorithm modifications for adaptive delay and loss response (TCP-ADaLR) to improve TCP performance. TCP-ADaLR incorporates delayed acknowledgement mechanism recommended for Internet hosts. We evaluate and compare the performance of TCP-ADaLR, TCP SACK, and TCP NewReno, with and without delayed ackno...

  13. ADA3 regulates normal and tumor mammary epithelial cell proliferation through c-MYC.

    Science.gov (United States)

    Griffin, Nicolas I; Sharma, Gayatri; Zhao, Xiangshan; Mirza, Sameer; Srivastava, Shashank; Dave, Bhavana J; Aleskandarany, Mohammed; Rakha, Emad; Mohibi, Shakur; Band, Hamid; Band, Vimla

    2016-11-16

    We have established the critical role of ADA3 as a coactivator of estrogen receptor (ER), as well as its role in cell cycle progression. Furthermore, we showed that ADA3 is predominantly nuclear in mammary epithelium, and in ER+, but is cytoplasmic in ER- breast cancers, the latter correlating with poor survival. However, the role of nuclear ADA3 in human mammary epithelial cells (hMECs), and in ER+ breast cancer cells, as well as the importance of ADA3 expression in relation to patient prognosis and survival in ER+ breast cancer have remained uncharacterized. We overexpressed ADA3 in hMECs or in ER+ breast cancer cells and assessed the effect on cell proliferation. The expression of ADA3 was analyzed then correlated with the expression of various prognostic markers, as well as survival of breast cancer patients. Overexpression of ADA3 in ER- hMECs as well as in ER+ breast cancer cell lines enhanced cell proliferation. These cells showed increased cyclin B and c-MYC, decreased p27 and increased SKP2 levels. This was accompanied by increased mRNA levels of early response genes c-FOS, EGR1, and c-MYC. Analysis of breast cancer tissue specimens showed a significant correlation of ADA3 nuclear expression with c-MYC expression. Furthermore, nuclear ADA3 and c-MYC expression together showed significant correlation with tumor grade, mitosis, pleomorphism, NPI, ER/PR status, Ki67 and p27 expression. Importantly, within ER+ cases, expression of nuclear ADA3 and c-MYC also significantly correlated with Ki67 and p27 expression. Univariate Kaplan Meier analysis of four groups in the whole, as well as the ER+ patients showed that c-MYC and ADA3 combinatorial phenotypes showed significantly different breast cancer specific survival with c-MYC-high and ADA3-Low subgroup had the worst outcome. Using multivariate analyses within the whole cohort and the ER+ subgroups, the significant association of ADA3 and c-MYC expression with patients' outcome was independent of tumor grade

  14. Autoimmune dysregulation and purine metabolism in adenosine deaminase (ADA-deficiency

    Directory of Open Access Journals (Sweden)

    Aisha Vanessa Sauer

    2012-08-01

    Full Text Available Genetic defects in the adenosine deaminase (ADA gene are among the most common causes for severe combined immunodeficiency (SCID. ADA-SCID patients suffer from lymphopenia, severely impaired cellular and humoral immunity, failure to thrive and recurrent infections. Currently available therapeutic options for this otherwise fatal disorder include bone marrow transplantation (BMT, enzyme replacement therapy with bovine ADA (PEG-ADA or hematopoietic stem cell gene therapy (HSC-GT. Although varying degrees of immune reconstitution can be achieved by these treatments, breakdown of tolerance is a major concern in ADA-SCID. Immune dysregulation such as autoimmune hypothyroidism, diabetes mellitus, hemolytic anemia, and immune thrombocytopenia are frequently observed in milder forms of the disease. However, several reports document similar complications also in patients on long-term PEG-ADA and after BMT or GT treatment.A skewed repertoire and decreased immune functions have been implicated in autoimmunity observed in certain B-cell and/or T-cell immunodeficiencies, but it remains unclear to what extent specific mechanisms of tolerance are affected in ADA deficiency. Herein we provide an overview about ADA-SCID and the autoimmune manifestations reported in these patients before and after treatment. We also assess the value of the ADA-deficient mouse model as a useful tool to study both immune and metabolic disease mechanisms. With focus on regulatory T and B cells we discuss the lymphocyte subpopulations particularly prone to contribute to the loss of self-tolerance and onset of autoimmunity in ADA deficiency. Moreover we address which aspects of immune dysregulation are specifically related to alterations in purine metabolism caused by the lack of ADA and the subsequent accumulation of metabolites with immunomodulatory properties.

  15. Towards a rAAV-based gene therapy for ADA-SCID: from ADA deficiency to current and future treatment strategies.

    Science.gov (United States)

    Silver, Jared N; Flotte, Terence R

    2008-07-01

    Adenosine deaminase deficiency fosters a rare, devastating pediatric immune deficiency with concomitant opportunistic infections, metabolic anomalies and multiple organ system pathology. The standard of care for adenosine deaminase deficient severe combined immune deficiency (ADA-SCID) includes enzyme replacement therapy or bone marrow transplantation. Gene therapies for ADA-SCID over nearly two decades have exclusively involved retroviral vectors targeted to lymphocytes and hematopoetic progenitors. These groundbreaking gene therapies represent a revolution in clinical medicine, but come with several challenges, including the risk of insertional mutagenesis. An alternative gene therapy for ADA-SCID may utilize recombinant adeno-associated virus vectors in vivo, with numerous target tissues, to foster ectopic expression and secretion of adenosine deaminase. This review endeavors to describe ADA-SCID, the traditional treatments, previous retroviral gene therapies, and primarily, alternative recombinant adeno-associated virus-based strategies to remedy this potentially fatal genetic disease.

  16. O tempo na terceira Enéada de Plotino

    OpenAIRE

    Daniel Schiochett

    2009-01-01

    Plotino é conhecido pela doutrina das três hipóstases: o Uno, a Inteligência e a Alma. Enquanto neoplatônico, sua doutrina é pensada a partir da visão platônica do mundo. Todavia, na terceira Enéada o filósofo se põe a discutir longamente a concepção antiga do tempo, fortemente devedora da doutrina aristotélica. Plotino, ao seu modo, consegue reinterpretar e adequar a noção aristotélica do tempo à concepção de mundo platônica. O tempo, para Plotino, por um lado, permanece referido ao moviment...

  17. The Alzheimer's Disease Assessment Scale-Cognitive-Plus (ADAS-Cog-Plus): an expansion of the ADAS-Cog to improve responsiveness in MCI.

    Science.gov (United States)

    Skinner, Jeannine; Carvalho, Janessa O; Potter, Guy G; Thames, April; Zelinski, Elizabeth; Crane, Paul K; Gibbons, Laura E

    2012-12-01

    The Alzheimer's Disease Assessment Scale cognitive subscale (ADAS-Cog) is widely used in AD, but may be less responsive to change when used in people with mild cognitive impairment (MCI). Participants from the Alzheimer's Disease Neuroimaging Initiative were administered a neuropsychological battery and 1.5 T MRI scans over 2-3 years. Informants were queried regarding functional impairments. Some participants had lumbar punctures to obtain cerebrospinal fluid (CSF). We added executive functioning (EF) and functional ability (FA) items to the ADAS-Cog to generate candidate augmented measures. We calibrated these candidates using baseline data (n = 811) and selected the best candidate that added EF items alone and that added EF and FA items. We selected candidates based on their responsiveness over three years in a training sample of participants with MCI (n = 160). We compared traditional ADAS-Cog scores with the two candidates based on their responsiveness in a validation sample of participants with MCI (n = 234), ability to predict conversion to dementia (n = 394), strength of association with baseline MRI (n = 394) and CSF biomarkers (n = 193). The selected EF candidate added category fluency (ADAS Plus EF), and the selected EF and FA candidate added category fluency, Digit Symbol, Trail Making, and five items from the Functional Assessment Questionnaire (ADAS Plus EF&FA). The ADAS Plus EF& FA performed as well as or better than traditional ADAS-Cog scores. Adding EF and FA items to the ADAS-Cog may improve responsiveness among people with MCI without impairing validity.

  18. Carrier frequency of a nonsense mutation in the adenosine deaminase (ADA) gene implies a high incidence of ADA-deficient severe combined immunodeficiency (SCID) in Somalia and a single, common haplotype indicates common ancestry

    DEFF Research Database (Denmark)

    Sanchez Sanchez, Juan Jose; Monaghan, Gemma; Børsting, Claus

    2007-01-01

    Inherited adenosine deaminase (ADA) deficiency is a rare metabolic disorder that causes immunodeficiency, varying from severe combined immunodeficiency (SCID) in the majority of cases to a less severe form in a small minority of patients. Five patients of Somali origin from four unrelated families......, with severe ADA-SCID, were registered in the Greater London area. Patients and their parents were investigated for the nonsense mutation Q3X (ADA c7C>T), two missense mutations K80R (ADA c239A>G) and R142Q (ADA c425G>A), and a TAAA repeat located at the 3' end of an Alu element (AluVpA) positioned 1.1 kb...... upstream of the ADA transcription start site. All patients were homozygous for the haplotype ADA-7T/ADA-239G/ADA-425G/AluVpA7. Among 207 Somali immigrants to Denmark, the frequency of ADA c7C>T and the maximum likelihood estimate of the frequency of the haplotype ADA-7T/ADA-239G/ADA-425G/AluVpA7 were both...

  19. 76 FR 12753 - Notice of Temporary Closures on Public Lands in Ada and Elmore Counties, ID

    Science.gov (United States)

    2011-03-08

    ... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLIDB00200 LF20000ES.JS0000 LFESFTF60000] Notice of Temporary Closures on Public Lands in Ada and Elmore Counties, ID AGENCY: Bureau of Land... business hours. SUPPLEMENTARY INFORMATION: The Big Fire closure affects public lands located in Ada County...

  20. Cartalk 2000: development of a co-operative ADAS based on vehicle-to-vehicle communication

    NARCIS (Netherlands)

    Morsink, P.L.J.; Hallouzi, R.; Dagli, I.; Cseh, C.; Schäfers, L.; Nelisse, M.W.; Bruin, D. de

    2003-01-01

    Advanced Driver Assistance Systems (ADAS) benefit from using vehicle-to-vehicle communication. In the 5th framework EC project CarTALK2000 co-operative ADAS are designed, tested and evaluated with respect to increasing traffic safety, efficiency and driving comfort. Communication based longitudinal

  1. 76 FR 57013 - Recordkeeping and Reporting Requirements Under Title VII, the ADA, and GINA

    Science.gov (United States)

    2011-09-15

    ... EQUAL EMPLOYMENT OPPORTUNITY COMMISSION 29 CFR Part 1602 RIN 3046-AA89 Recordkeeping and Reporting Requirements Under Title VII, the ADA, and GINA AGENCY: Equal Employment Opportunity Commission. ACTION... under title VII, the ADA, and GINA. (76 FR 31892, June 2, 2011). No requests to present oral testimony...

  2. The Labor Market Experience of Workers with Disabilities: The ADA and Beyond.

    Science.gov (United States)

    Hotchkiss, Julie L.

    This book provides a comprehensive analysis of the recent labor market experience of American workers with disabilities and an assessment of the impact the Americans with Disabilities Act (ADA) has had on that experience. Since one intention of the ADA is to break down barriers to employment for the disabled, the analyses focus on labor demand…

  3. Storage management in Ada. Three reports. Volume 1: Storage management in Ada as a risk to the development of reliable software. Volume 2: Relevant aspects of language. Volume 3: Requirements of the language versus manifestations of current implementations

    Science.gov (United States)

    Auty, David

    1988-01-01

    The risk to the development of program reliability is derived from the use of a new language and from the potential use of new storage management techniques. With Ada and associated support software, there is a lack of established guidelines and procedures, drawn from experience and common usage, which assume reliable behavior. The risk is identified and clarified. In order to provide a framework for future consideration of dynamic storage management on Ada, a description of the relevant aspects of the language is presented in two sections: Program data sources, and declaration and allocation in Ada. Storage-management characteristics of the Ada language and storage-management characteristics of Ada implementations are differentiated. Terms that are used are defined in a narrow and precise sense. The storage-management implications of the Ada language are described. The storage-management options available to the Ada implementor and the implications of the implementor's choice for the Ada programmer are also described.

  4. Epidermal Growth Factor Receptor activation promotes ADA3 acetylation through the AKT-p300 pathway.

    Science.gov (United States)

    Srivastava, Shashank; Mohibi, Shakur; Mirza, Sameer; Band, Hamid; Band, Vimla

    2017-08-18

    The ADA3 (Alteration/Deficiency in Activation 3) protein is an essential adaptor component of several Lysine Acetyltransferase (KAT) complexes involved in chromatin modifications. Previously, we and others have demonstrated a crucial role of ADA3 in cell cycle progression and in maintenance of genomic stability. Recently, we have shown that acetylation of ADA3 is key to its role in cell cycle progression. Here, we demonstrate that AKT activation downstream of Epidermal Growth Factor Receptor (EGFR) family proteins stimulation leads to phosphorylation of p300, which in turn promotes the acetylation of ADA3. Inhibition of upstream receptor tyrosine kinases (RTKs), HER1 (EGFR)/HER2 by lapatinib and the accompanying reduction of phospho-AKT levels led to a decrease in p300 phosphorylation and ADA3 protein levels. The p300/PCAF inhibitor garcinol also destabilized the ADA3 protein in a proteasome-dependent manner and an ADA3 mutant with K→R mutations exhibited a marked increase in half-life, consistent with opposite role of acetylation and ubiquitination of ADA3 on shared lysine residues. ADA3 knockdown led to cell cycle inhibitory effects, as well as apoptosis similar to those induced by lapatinib treatment of HER2+ breast cancer cells, as seen by accumulation of CDK inhibitor p27, reduction in mitotic marker pH3(S10), and a decrease in the S-phase marker PCNA, as well as the appearance of cleaved PARP. Taken together our results reveal a novel RTK-AKT-p300-ADA3 signaling pathway involved in growth factor-induced cell cycle progression.

  5. Research, development, training, and education using the Ada programming language. Final report, 1 September 1987-31 May 1989

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, G.C.

    1989-07-16

    The primary goal of this activity was to conduct research in the application and development of Ada, and in broader terms the objectives were as follows: (1) To develop numerical algorithms for parallel processing using the Ada language; (2) To develop new methodologies in reusing Ada software; (3) To solve select problems in applied mathematics using MACSYMA and Ada; (4) Simulate the interactions of nodes in a network using Ada; (5) To increase the cadre of educations available to provide Ada training by conducting Ada workshops for Norfolk State University faculty and staff; (6) To develop a series of in-class and individualized modules addressing Ada programming using computer-assisted instruction; and (7) To disseminate research and computer-aided instruction modules to other minority institutions through computer networking, workshops, and lecture series.

  6. The ada operon of Mycobacterium tuberculosis encodes two DNA methyltransferases for inducible repair of DNA alkylation damage.

    Science.gov (United States)

    Yang, Mingyi; Aamodt, Randi M; Dalhus, Bjørn; Balasingham, Seetha; Helle, Ina; Andersen, Pernille; Tønjum, Tone; Alseth, Ingrun; Rognes, Torbjørn; Bjørås, Magnar

    2011-06-10

    The ada operon of Mycobacterium tuberculosis, which encodes a composite protein of AdaA and AlkA and a separate AdaB/Ogt protein, was characterized. M. tuberculosis treated with N-methyl-N'-nitro-N-nitrosoguanidine induced transcription of the adaA-alkA and adaB genes, suggesting that M. tuberculosis mount an inducible response to methylating agents. Survival assays of the methyltransferase defective Escherichia coli mutant KT233 (ada ogt), showed that expression of the adaB gene rescued the alkylation sensitivity. Further, adaB but not adaA-alkA complemented the hypermutator phenotype of KT233. Purified AdaA-AlkA and AdaB possessed methyltransferase activity. These data suggested that AdaB counteract the cytotoxic and mutagenic effect of O(6)-methylguanine, while AdaA-AlkA most likely transfers methyl groups from innocuous methylphosphotriesters. AdaA-AlkA did not possess alkylbase DNA glycosylase activity nor rescue the alkylation sensitivity of the E. coli mutant BK2118 (tag alkA). We propose that AdaA-AlkA is a positive regulator of the adaptive response in M. tuberculosis. It thus appears that the ada operon of M. tuberculosis suppresses the mutagenic effect of alkylation but not the cytotoxic effect of lesions such as 3-methylpurines. Collectively, these data indicate that M. tuberculosis hypermutator strains with defective adaptive response genes might sustain robustness to cytotoxic alkylation DNA damage and confer a selective advantage contributing to host adaptation. Copyright © 2011 Elsevier B.V. All rights reserved.

  7. AdaBoost-based algorithm for network intrusion detection.

    Science.gov (United States)

    Hu, Weiming; Hu, Wei; Maybank, Steve

    2008-04-01

    Network intrusion detection aims at distinguishing the attacks on the Internet from normal use of the Internet. It is an indispensable part of the information security system. Due to the variety of network behaviors and the rapid development of attack fashions, it is necessary to develop fast machine-learning-based intrusion detection algorithms with high detection rates and low false-alarm rates. In this correspondence, we propose an intrusion detection algorithm based on the AdaBoost algorithm. In the algorithm, decision stumps are used as weak classifiers. The decision rules are provided for both categorical and continuous features. By combining the weak classifiers for continuous features and the weak classifiers for categorical features into a strong classifier, the relations between these two different types of features are handled naturally, without any forced conversions between continuous and categorical features. Adaptable initial weights and a simple strategy for avoiding overfitting are adopted to improve the performance of the algorithm. Experimental results show that our algorithm has low computational complexity and error rates, as compared with algorithms of higher computational complexity, as tested on the benchmark sample data.

  8. 76 FR 66034 - Proposed Foreign-Trade Zone-Ada and Canyon Counties, ID, Under Alternative Site Framework...

    Science.gov (United States)

    2011-10-25

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket 65-2011] Proposed Foreign-Trade Zone--Ada... establish a general-purpose foreign-trade zone at sites in Ada and Canyon Counties, Idaho, adjacent to the... proposed service area under the ASF would be Ada and Canyon Counties, Idaho. If approved, the applicant...

  9. 77 FR 46008 - Approval and Promulgation of State Implementation Plans: Idaho; Boise-Northern Ada County Air...

    Science.gov (United States)

    2012-08-02

    ... Promulgation of State Implementation Plans: Idaho; Boise-Northern Ada County Air Quality Maintenance Area... the Northern Ada County Air Quality Maintenance Area Second 10-year Carbon Monoxide Maintenance Plan...-Northern Ada County Air Quality Maintenance Area will maintain air quality standards for carbon monoxide...

  10. 76 FR 53705 - Notice To Rescind a Notice of Intent To Prepare an Environmental Impact Statement (EIS), Ada...

    Science.gov (United States)

    2011-08-29

    ... To Prepare an Environmental Impact Statement (EIS), Ada County, ID AGENCY: Federal Highway... Statement (EIS) for a proposed highway project in Ada County, Idaho is being rescinded. FOR FURTHER... Manager, Ada County Highway District, 318 East 37th Street, Garden City, ID 83714, telephone (208) 387...

  11. 77 FR 45962 - Approval and Promulgation of State Implementation Plans: Idaho; Boise-Northern Ada County Air...

    Science.gov (United States)

    2012-08-02

    ... Promulgation of State Implementation Plans: Idaho; Boise-Northern Ada County Air Quality Maintenance Area... (IDEQ) submitted the Northern Ada County Air Quality Maintenance Area Second 10-year Carbon Monoxide... Ada County Air Quality Maintenance Area will maintain air quality standards for carbon monoxide (CO...

  12. 76 FR 14745 - Notice To Rescind a Notice of Intent To Prepare an Environmental Impact Statement, Ada and Canyon...

    Science.gov (United States)

    2011-03-17

    ... To Prepare an Environmental Impact Statement, Ada and Canyon Counties, ID AGENCY: Federal Highway... prepare an Environmental Impact Statement for a proposed highway project in Ada and Canyon County, Idaho... Highway 44 from Exit 25 at Interstate 84 in Canyon County to Ballantyne Lane in Ada County. The project is...

  13. CITY GROUND DESIGN AND THE IMAGE OF THE CITY: THE PORTUGUESE CALÇADA

    Directory of Open Access Journals (Sweden)

    Antoni Remesar

    2014-10-01

    The pavement-form - including the "calçada-form"-is at the root of some of the flagship operations creating the image of the city (Havana, 1928; Alicante, 1957; the Ramblas in Barcelona, 1969; reform of the Avenida Atlantica in Rio by Burle Marx, 1970. However, these same operations show that the "form-calçada" does not meet many of the requirements of economy, security or universal accessibility required by the contemporary city. In the paper was to analyze the causes and reasons that hover over the announced death of calçada á Portugueza.

  14. Ada compiler evaluation on the Space Station Freedom Software Support Environment project

    Science.gov (United States)

    Badal, D. L.

    1989-01-01

    This paper describes the work in progress to select the Ada compilers for the Space Station Freedom Program (SSFP) Software Support Environment (SSE) project. The purpose of the SSE Ada compiler evaluation team is to establish the criteria, test suites, and benchmarks to be used for evaluating Ada compilers for the mainframes, workstations, and the realtime target for flight- and ground-based computers. The combined efforts and cooperation of the customer, subcontractors, vendors, academia and SIGAda groups made it possible to acquire the necessary background information, benchmarks, test suites, and criteria used.

  15. The ADAS-Cog revisited: novel composite scales based on ADAS-Cog to improve efficiency in MCI and early AD trials.

    Science.gov (United States)

    Raghavan, Nandini; Samtani, Mahesh N; Farnum, Michael; Yang, Eric; Novak, Gerald; Grundman, Michael; Narayan, Vaibhav; DiBernardo, Allitia

    2013-02-01

    The Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) has been used widely as a cognitive end point in Alzheimer's Disease (AD) clinical trials. Efforts to treat AD pathology at earlier stages have also used ADAS-Cog, but failure in these trials can be difficult to interpret because the scale has well-known ceiling effects that limit its use in mild cognitive impairment (MCI) and early AD. A wealth of data exists in ADAS-Cog from both historical trials and contemporary longitudinal natural history studies that can provide insights about parts of the scale that may be better suited for MCI and early AD trials. Using Alzheimer's Disease Neuroimaging Initiative study data, we identified the most informative cognitive measures from the ADAS-Cog and other available scales. We used cross-sectional analyses to characterize trajectories of ADAS-Cog and its individual subscales, as well as other cognitive, functional, or global measures across disease stages. Informative measures were identified based on standardized mean of 2-year change from baseline and were combined into novel composite endpoints. We assessed performance of the novel endpoints based on sample size requirements for a 2-year clinical trial. A bootstrap validation procedure was also undertaken to assess the reproducibility of the standardized mean changes of the selected measures and the corresponding composites. All proposed novel endpoints have improved standardized mean changes and thus improved statistical power compared with the ADAS-Cog 11. Further improvements were achieved by using cognitive-functional composites. Combining the novel composites with an enrichment strategy based on cerebral spinal fluid beta-amyloid (Aβ(1-42)) in a 2-year trial yielded gains in power of 20% to 40% over ADAS-Cog 11, regardless of the novel measure considered. An empirical, data-driven approach with existing instruments was used to derive novel composite scales based on ADAS-Cog 11 with improved performance

  16. 78 FR 67303 - Americans With Disabilities Act (ADA) Accessibility Guidelines for Buildings and Facilities...

    Science.gov (United States)

    2013-11-12

    ... ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD 36 CFR Part 1191 RIN 3014-AA22 Americans With Disabilities Act (ADA) Accessibility Guidelines for Buildings and Facilities; Architectural Barriers Act (ABA) Accessibility Guidelines; Correction AGENCY: Architectural and Transportation Barriers...

  17. 75 FR 18781 - Americans With Disabilities Act (ADA) Accessibility Guidelines for Buildings and Facilities...

    Science.gov (United States)

    2010-04-13

    ... ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD 36 CFR Parts 1191, 1193, and 1194 [Docket No. 2010-1] RIN 3014-AA37 Americans With Disabilities Act (ADA) Accessibility Guidelines for Buildings and Facilities; Telecommunications Act Accessibility Guidelines; Electronic and Information...

  18. Fine-Tuning ADAS Algorithm Parameters for Optimizing Traffic Safety and Mobility in Connected Vehicle Environment

    Science.gov (United States)

    With the development of Connected Vehicle Technology that facilitates wireless communication among vehicles and road-side infrastructure, the Advanced Driver Assistance Systems (ADAS) can be adopted as an effective tool for accelerating traffic safety and mobility optimization at...

  19. Errors in ADAS-cog administration and scoring may undermine clinical trials results.

    Science.gov (United States)

    Schafer, K; De Santi, S; Schneider, L S

    2011-06-01

    The Alzheimer's Disease Assessment Scale - cognitive subscale (ADAS-cog) is the most widely used cognitive outcome measure in AD trials. Although errors in administration and scoring have been suggested as factors masking accurate estimates and potential effects of treatments, there have been few formal examinations of errors with the ADAS-cog. We provided ADAS-cog administration training using standard methods to raters who were designated as experienced, potential raters by sponsors or contract research organizations for two clinical trials. Training included 1 hour sessions on test administration, scoring, question periods, and required that raters individually view and score a model ADAS-cog administration. Raters scores were compared to the criterion scores established for the model administration. A total of 108 errors were made by 80.6% of the 72 raters; 37.5% made 1 error, 25.0% made 2 errors and 18.0% made 3 or more. Errors were made in all ADAS-cog subsections. The most common were in word finding difficulty (67% of the raters), word recognition (22%), and orientation (22%). For the raters who made 1, 2, or ≥ 3 errors the ADAS-cog score was 17.5 (95% CI, 17.3 - 17.8), 17.8 (17.0 - 18.5), and 18.8 (17.6 - 20.0), respectively, and compared to the criterion score, 18.3. ADAS-cog means differed significantly and the variances were more than twice as large between those who made errors on word finding and those who did not, 17.6 (SD=1.4) vs. 18.8 (SD=0.9), respectively (χ(2) = 37.2, P ADAS-cog scores and clinical trials outcomes. These errors may undermine detection of medication effects by contributing both to a biased point estimate and increased variance of the outcome.

  20. What is the clinically relevant change on the ADAS-Cog?

    Science.gov (United States)

    Schrag, Anette; Schott, Jonathan M

    2012-02-01

    To establish the minimal clinically relevant change (MCRC) on the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) for patients with mild Alzheimer's disease (AD). Cohort study. 59 recruiting sites for the Alzheimer's Disease Neuroimaging Initiative. Outpatients with AD in the Alzheimer's Disease Neuroimaging Initiative. The authors applied anchor-based MCRC methodology comparing ADAS-Cog change against clinicians' judgement of clinically relevant worsening between baseline and 6 months in four domains: memory and non-memory cognitive performance; Clinical Dementia Rating Scale; and Functional Assessment Questionnaire. The analysis was repeated for the 6-12-month interval. To support these findings, the authors calculated distribution-based measures including half-baseline SD (1/2 SD) and SEM. 181 patients (baseline ADAS-Cog score 18.5±6.4) had ADAS-Cog data at 0 and 6 months. Those undergoing clinically significant worsening on any of the four anchor questions (n=41-47) had an average ADAS-Cog change of 3.1-3.8 points. Similar results were found for the 177 patients with 6-12-month data. The average 1/2 SD for the baseline ADAS-Cog score was 3.2, and the SEM was 3.7. 3 points decline on the ADAS-Cog may be an appropriate MCRC for clinical trials of patients with early AD. However, further studies assessing the MCRC for improvement on the ADAS-Cog, using patient-based judgement as an anchor, and determining the minimal clinically relevant difference between change on two treatments are required. http://clinicalTrials.gov Identifier: NCT00106899.

  1. 75 FR 45661 - Notice of Permanent Closure on Public Lands in Ada County, ID

    Science.gov (United States)

    2010-08-03

    ... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLIDB00100 L17110000.PH0000 241A 4500013040] Notice of Permanent Closure on Public Lands in Ada County, ID AGENCY: Bureau of Land Management, Interior.../2\\NW\\1/4\\ NW\\1/4\\ and N\\1/2\\SW\\1/4\\ NW\\1/4\\ of Section 32, T.1 S., R.3 E., Boise Meridian, Ada...

  2. A study of the portability of an Ada system in the software engineering laboratory (SEL)

    Science.gov (United States)

    Jun, Linda O.; Valett, Susan Ray

    1990-01-01

    A particular porting effort is discussed, and various statistics on analyzing the portability of Ada and the total staff months (overall and by phase) required to accomplish the rehost, are given. This effort is compared to past experiments on the rehosting of FORTRAN systems. The discussion includes an analysis of the types of errors encountered during the rehosting, the changes required to rehost the system, experiences with the Alsys IBM Ada compiler, the impediments encountered, and the lessons learned during this study.

  3. A-D-A small molecules for solution-processed organic photovoltaic cells.

    Science.gov (United States)

    Ni, Wang; Wan, Xiangjian; Li, Miaomiao; Wang, Yunchuang; Chen, Yongsheng

    2015-03-25

    A-D-A small molecules have drawn more and more attention in solution-processed organic solar cells due to the advantages of a diversity of structures, easy control of energy levels, etc. Recently, a power conversion efficiency of nearly 10% has been achieved through careful material design and device optimization. This feature article reviews recent representative progress in the design and application of A-D-A small molecules in organic photovoltaic cells.

  4. [Diagnostic value and functional correlations of the ADAS-Cog scale in Alzheimer's disease: data on NORMACODEM project].

    Science.gov (United States)

    Monllau, A; Pena-Casanova, J; Blesa, R; Aguilar, M; Bohm, P; Sol, J M; Hernandez, G

    2007-10-01

    The aims of this study were to assess the criterion validity of Alzheimer's Disease Assessment Scale (ADAS) and its cognitive subscale (ADAS-Cog) for the diagnosis of Alzheimer's disease (AD), and to determine their different cut-off scores and sensitivity and specificity values. In addition, we also attempted to study the possible correlations between cognitive scores (ADAS) and functional measures. 451 subjects were studied (254 controls, 86 subjects with mild cognitive impairment and 111 patients with AD). ADAS total score was obtained by adding the cognitive (ADAS-Cog) and non-cognitive (ADAS-Nocog) scales. Scores were adjusted for age and formal education. For assessing the possible correlation between cognitive and functional measures, the following instruments were administered: Rapid Disability Rating Scale-2 (RDRS-2), Blessed Dementia Rating Scale (BDRS) and the Interview for the Deterioration of Daily Living in Dementia (IDDD). ROC curves and Pearson correlation coefficient. ADAS best cut-off score for dementia was > or = 17 providing sensitivity and specificity values of 90.09% and 85.88 % respectively, while for the ADAS-Cog best cut-off score was > or = 12 with sensitivity and specificity values of 89.19 % and 88.53 % respectively. In both cases scores were adjusted for age and formal education. The area under the ROC curve was 0.95 and 0.94 respectively. Highly significant correlations were found for ADAS and 19 ADAS-Cog with the functional scales studied. Both, ADAS and ADAS-Cog report good validity in terms of sensitivity, specificity and as predictive value for AD. Moreover, significant correlations were found between the functional impairment observed in patients with AD and the overall scores achieved in the ADAS and ADAS-Cog.

  5. Constructing a working taxonomy of functional Ada software components for real-time embedded system applications

    Science.gov (United States)

    Wallace, Robert

    1986-01-01

    A major impediment to a systematic attack on Ada software reusability is the lack of an effective taxonomy for software component functions. The scope of all possible applications of Ada software is considered too great to allow the practical development of a working taxonomy. Instead, for the purposes herein, the scope of Ada software application is limited to device and subsystem control in real-time embedded systems. A functional approach is taken in constructing the taxonomy tree for identified Ada domain. The use of modular software functions as a starting point fits well with the object oriented programming philosophy of Ada. Examples of the types of functions represented within the working taxonomy are real time kernels, interrupt service routines, synchronization and message passing, data conversion, digital filtering and signal conditioning, and device control. The constructed taxonomy is proposed as a framework from which a need analysis can be performed to reveal voids in current Ada real-time embedded programming efforts for Space Station.

  6. An Ada-based preprocessor language for concurrent object oriented programming

    International Nuclear Information System (INIS)

    Almulla, M.; Al-Haddad, M.; Loeper, H.

    2001-01-01

    In this paper, implementation issues of concurrent-objected programming using Ada 95 are addressed. Ada is not a pure object-oriented language; in order to make it so, a uniform template for structuring object classes is proposed. The template constitutes a basis for an Ada-based preprocessor language that handles concurrent object-oriented programming. The preprocessor accepts Ada-like object-oriented programs (object classes, subclasses and main program) as input and produces Ada 95 concurrent object-oriented program units as output. The preprocessor language has the advantage of adding a new component to the class specification called the protocol, which specifies the order for requesting methods f an object. The preprocessor also touches on the extensibility of object classes issue. It supports defining class hierarchies by inheritance and aggregation. In addition, the preprocessor language supports the re-use of Ada packages, which are not necessarily written according to the object-oriented approach. The paper also investigates the definition of circular dependent object classes and proposes a solution for introducing a collection of classes. (author)

  7. Predictive value of 6-month decline in ADAS-cog for survival without severe Alzheimer's disease.

    Science.gov (United States)

    Helmer, Catherine; Andrieu, Sandrine; Pérès, Karine; Orgogozo, Jean-Marc; Vellas, Bruno; Dartigues, Jean-François

    2007-01-01

    To determine the predictive value of the 6-month evolution of the ADAS-cog score in initially mild to moderate Alzheimer's disease (AD) patients on the risk of death or severe dementia (MMSE ADAS-cog scale in the Real.fr study, a cohort of AD patients. Six classes of ADAS-cog evolution were distinguished, from the severest deterioration (decline >or=7 points) to the greatest cognitive improvement (gain >or=4 points). Among 536 AD patients, 53 (9.9%) had a 6-month decline of 7 points or more. This group with the severest deterioration was significantly associated with the risk of severe dementia or death at 2 years (relative risk, RR = 3.8, 95% confidence interval, CI = 2.1-6.8), even after adjustment for baseline MMSE, disability and ADAS-cog score (RR = 2.6, 95% CI = 1.4-5.0). In addition, subjects with a decline by at least 4 points were also at greater risk of severe dementia. These results confirm the value of the ADAS-cog scale as a judgement criterion in clinical trials since it is a good surrogate marker of long-term prognosis. The proportion of fast decliners on the ADAS-cog could be a helpful judgement criterion for future trials in AD.

  8. Improved utilization of ADAS-cog assessment data through item response theory based pharmacometric modeling.

    Science.gov (United States)

    Ueckert, Sebastian; Plan, Elodie L; Ito, Kaori; Karlsson, Mats O; Corrigan, Brian; Hooker, Andrew C

    2014-08-01

    This work investigates improved utilization of ADAS-cog data (the primary outcome in Alzheimer's disease (AD) trials of mild and moderate AD) by combining pharmacometric modeling and item response theory (IRT). A baseline IRT model characterizing the ADAS-cog was built based on data from 2,744 individuals. Pharmacometric methods were used to extend the baseline IRT model to describe longitudinal ADAS-cog scores from an 18-month clinical study with 322 patients. Sensitivity of the ADAS-cog items in different patient populations as well as the power to detect a drug effect in relation to total score based methods were assessed with the IRT based model. IRT analysis was able to describe both total and item level baseline ADAS-cog data. Longitudinal data were also well described. Differences in the information content of the item level components could be quantitatively characterized and ranked for mild cognitively impairment and mild AD populations. Based on clinical trial simulations with a theoretical drug effect, the IRT method demonstrated a significantly higher power to detect drug effect compared to the traditional method of analysis. A combined framework of IRT and pharmacometric modeling permits a more effective and precise analysis than total score based methods and therefore increases the value of ADAS-cog data.

  9. Proceedings of the Annual National Conference on Ada (Trademark) Technology (3rd) Held at Prarie View, Texas on 20-21 March 1985.

    Science.gov (United States)

    1985-01-01

    umeints WEIGHT SUMMNATION Figure 3. Ada Decision Matrix 90 Annual National Confefence on Ada Technology 1985 2., - .. ° •- , - Well written Ada code will...languages. candidates for recovery to the target environment is generated. Annual National Confefence on Ada Technology 1985 153 -.. • . . . .o

  10. Clinical significance of determination of serum HA, PCIII and ADA levels in patients with chronic hepatitis C

    International Nuclear Information System (INIS)

    Zhang Jing; Yu Fan; Zhao Changxin

    2006-01-01

    Objective: To explore the changes of serum HA, PCIII and ADA levels in patients with chronic hepatitis C. Methods: Serum HA, PCIII and ADA levels were detected with RIA in 42 cases with chronic hepatitis C and 35 controls. Results: The levels of serum HA, PC III and ADA in the patients were significantly higher than those in controls (P<0.01). Serum HA, PC m and ADA levels were positive correlated (r=0.6178, 0.6211, P<0.01). Conclusion: The results suggested the serum HA, PC m and ADA levels can reflect the degree of hepatic injury in the patients with cirrhosis, detection of serum HA, PC m and ADA levels is helpful in estimating the status of the disease. (authors)

  11. Revising the ADAS-cog for a more accurate assessment of cognitive impairment.

    Science.gov (United States)

    Wouters, Hans; van Gool, Willem A; Schmand, Ben; Lindeboom, Robert

    2008-01-01

    To examine whether it is appropriate to sum the cognitive part of the Alzheimer Disease Assessment Scale (ADAS-cog) items to assess cognitive impairment. This assumes items to have (1) equal measurement precision and (2) hierarchically ordered categories. Rasch analysis on the basis of pooled data from 3 Randomized Controlled Trials was used to examine these assumptions and to estimate each patient's level of impairment. Analyses were replicated in an independent sample. The original ADAS-cog scoring did not fit the Rasch Model and did not reliably distinguish between impairment levels. Patients with equal test scores had different impairment levels. Similarly, patients with different test scores could have the same impairment level. Revising the ADAS-cog by (1) weighting the items by their measurement precision and (2) collapsing nonhierarchical item categories resulted in good fit and a valid one to one correspondence between sum scores and estimated impairment levels. This revealed that equal differences in ADAS-cog scores did not reflect equal differences in impairment level along the test's score range. It is appropriate to summate the ADAS-cog items provided that the items are weighted and have their categories hierarchically ordered.

  12. Optimizing ADAS-Cog Worksheets: A Survey of Clinical Trial Rater s' Perceptions.

    Science.gov (United States)

    Meyer, Stephen M; Bertzos, Kristina A; Perez, Magdalena; Connor, Donald J; Schafer, Kimberly; Walter, Sarah

    2017-01-01

    The Alzheimer's Disease Assessment Scale-Cognitive subscale (ADASCog) remains the most widely used test of longitudinal cognitive functioning in Alzheimer's disease (AD) clinical trials. Unlike most neuropsychological tests, the ADAS-Cog source documentation worksheets are not uniform across clinical trials, and vary by document layout, inclusion of administration and/or scoring instructions, and documentation of subtest scoring (e.g., recording correct versus incorrect scores), among other differences. Many ADAS-Cog test administrators (raters) participate in multiple AD trials and switching between different ADAS-Cog worksheets may increase the likelihood of administration and/or scoring mistakes that lessen the reliability of the instrument. An anonymous online survey sought raters' experiences with ADAS-Cog worksheets and their opinions on the design and content of the worksheets. Results of the survey indicated preference for structure and standardization of the ADASCog worksheets, which has been considered in the development of a standard ADAS-Cog source document by the Alzheimer's Disease Cooperative Study (ADCS) Working Group. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  13. Autologous transplants of Adipose-Derived Adult Stromal (ADAS) cells afford dopaminergic neuroprotection in a model of Parkinson's disease.

    Science.gov (United States)

    McCoy, Melissa K; Martinez, Terina N; Ruhn, Kelly A; Wrage, Philip C; Keefer, Edward W; Botterman, Barry R; Tansey, Keith E; Tansey, Malú G

    2008-03-01

    Adult adipose contains stromal progenitor cells with neurogenic potential. However, the stability of neuronal phenotypes adopted by Adipose-Derived Adult Stromal (ADAS) cells and whether terminal neuronal differentiation is required for their consideration as alternatives in cell replacement strategies to treat neurological disorders is largely unknown. We investigated whether in vitro neural induction of ADAS cells determined their ability to neuroprotect or restore function in a lesioned dopaminergic pathway. In vitro-expanded naïve or differentiated ADAS cells were autologously transplanted into substantia nigra 1 week after an intrastriatal 6-hydroxydopamine injection. Neurochemical and behavioral measures demonstrated neuroprotective effects of both ADAS grafts against 6-hydroxydopamine-induced dopaminergic neuron death, suggesting that pre-transplantation differentiation of the cells does not determine their ability to survive or neuroprotect in vivo. Therefore, we investigated whether equivalent protection by naïve and neurally-induced ADAS grafts resulted from robust in situ differentiation of both graft types into dopaminergic fates. Immunohistological analyses revealed that ADAS cells did not adopt dopaminergic cell fates in situ, consistent with the limited ability of these cells to undergo terminal differentiation into electrically active neurons in vitro. Moreover, re-exposure of neurally-differentiated ADAS cells to serum-containing medium in vitro confirmed ADAS cell phenotypic instability (plasticity). Lastly, given that gene expression analyses of in vitro-expanded ADAS cells revealed that both naïve and differentiated ADAS cells express potent dopaminergic survival factors, ADAS transplants may have exerted neuroprotective effects by production of trophic factors at the lesion site. ADAS cells may be ideal for ex vivo gene transfer therapies in Parkinson's disease treatment.

  14. Ada (Trade Name) Compiler Validation Summary Report: Alsys Inc., AlsyCOMP 003, V3.1, HP Vectra.

    Science.gov (United States)

    1988-06-04

    Capability, ACVC, Validation Testing , Ada Validation Office, AVO, Ada Validation Facility, AVF, ANSI/MIL-STD- 1815A, Ada Joint Program Office, AJPO 20...CLASSIFICATION OF THIS PAGE (When Data Enrered) AVF Control Number: AVF-VSR-90502/26 Afla , COMPILER VALIDACION SUMMARY REPORT Alsys Inc AlsyCOMP .003, N73...HP Veutta Completion of On--Site Testing 4 June 1987 Prepared By The National Computing Centre Limited Oxford Road Manchester M1 7ED UK Prepared For

  15. Acetylation of Mammalian ADA3 Is Required for Its Functional Roles in Histone Acetylation and Cell Proliferation.

    Science.gov (United States)

    Mohibi, Shakur; Srivastava, Shashank; Bele, Aditya; Mirza, Sameer; Band, Hamid; Band, Vimla

    2016-10-01

    Alteration/deficiency in activation 3 (ADA3) is an essential component of specific histone acetyltransferase (HAT) complexes. We have previously shown that ADA3 is required for establishing global histone acetylation patterns and for normal cell cycle progression (S. Mohibi et al., J Biol Chem 287:29442-29456, 2012, http://dx.doi.org/10.1074/jbc.M112.378901). Here, we report that these functional roles of ADA3 require its acetylation. We show that ADA3 acetylation, which is dynamically regulated in a cell cycle-dependent manner, reflects a balance of coordinated actions of its associated HATs, GCN5, PCAF, and p300, and a new partner that we define, the deacetylase SIRT1. We use mass spectrometry and site-directed mutagenesis to identify major sites of ADA3 acetylated by GCN5 and p300. Acetylation-defective mutants are capable of interacting with HATs and other components of HAT complexes but are deficient in their ability to restore ADA3-dependent global or locus-specific histone acetylation marks and cell proliferation in Ada3-deleted murine embryonic fibroblasts (MEFs). Given the key importance of ADA3-containing HAT complexes in the regulation of various biological processes, including the cell cycle, our study presents a novel mechanism to regulate the function of these complexes through dynamic ADA3 acetylation. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  16. Pegademase bovine (PEG-ADA for the treatment of infants and children with severe combined immunodeficiency (SCID

    Directory of Open Access Journals (Sweden)

    Claire Booth

    2009-06-01

    Full Text Available Claire Booth1,2, H Bobby Gaspar1,21Centre for Immunodeficiency, Molecular Immunology Unit, UCL Institute of Child Health, London, UK; 2Dept of Clinical Immunology, Great Ormond Street Hospital NHS Trust, London, UKAbstract: Adenosine deaminase deficiency (ADA is a rare, inherited disorder of purine metabolism characterized by immunodeficiency, failure to thrive and metabolic abnormalities. A lack of the enzyme ADA allows accumulation of toxic metabolites causing defects of both cell mediated and humoral immunity leading to ADA severe combined immune deficiency (SCID, a condition that can be fatal in early infancy if left untreated. Hematopoietic stem cell transplant is curative but is dependent on a good donor match. Other therapeutic options include enzyme replacement therapy (ERT with pegademase bovine (PEG-ADA and more recently gene therapy. PEG-ADA has been used in over 150 patients worldwide and has allowed stabilization of patients awaiting more definitive treatment with hematopoietic stem cell transplant. It affords both metabolic detoxification and protective immune function with patients remaining clinically well, but immune reconstitution is often suboptimal and may not be long lived. We discuss the pharmacokinetics, immune reconstitution, effects on systemic disease and side effects of treatment with PEG-ADA. We also review the long-term outcome of patients receiving ERT and discuss the role of PEG-ADA in the management of infants and children with ADA-SCID, alongside other therapeutic options.Keywords: adenosine deaminase deficiency, PEG-ADA, enzyme replacement therapy, severe combined immune deficiency (SCID

  17. Selecting frequency feature for license plate detection based on AdaBoost

    Science.gov (United States)

    Tan, Huachun; Chen, Hao; Deng, Yafeng; Liu, Junhui

    2009-01-01

    In this paper, a new method for license plate detection based on AdaBoost is proposed. In the new method, character frequency feature, which is powerful feature for detecting license plate character, are introduced to feature pool. The frequency features obtained from the FFT of horizontal projection of binary image are selected by AdaBoost. Then, Haar-like features selected by AdaBoost are used to capture subtle structure of license plate. Furthermore, considering the characteristic of Chinese license plate that there are two types of license plate: deeper background-lighter character and lighter background-deeper character license plates, two detectors are designed to extract different license plates respectively. Experimental results show the efficiency of the proposed method.

  18. An enhanced Ada run-time system for real-time embedded processors

    Science.gov (United States)

    Sims, J. T.

    1991-01-01

    An enhanced Ada run-time system has been developed to support real-time embedded processor applications. The primary focus of this development effort has been on the tasking system and the memory management facilities of the run-time system. The tasking system has been extended to support efficient and precise periodic task execution as required for control applications. Event-driven task execution providing a means of task-asynchronous control and communication among Ada tasks is supported in this system. Inter-task control is even provided among tasks distributed on separate physical processors. The memory management system has been enhanced to provide object allocation and protected access support for memory shared between disjoint processors, each of which is executing a distinct Ada program.

  19. Evaluating rivastigmine in mild-to-moderate Parkinson's disease dementia using ADAS-cog items.

    Science.gov (United States)

    Schmitt, Frederick A; Aarsland, Dag; Brønnick, Kolbjørn S; Meng, Xiangyi; Tekin, Sibel; Olin, Jason T

    2010-08-01

    Rivastigmine has been shown to improve cognition in patients with Parkinson's disease dementia (PDD). To further explore the impact of anticholinesterase therapy on PDD, Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) items were assessed in a retrospective analysis of a 24-week, double-blind, placebo-controlled trial of rivastigmine. Mean changes from baseline at week 24 were calculated for ADAS-cog item scores and for 3 cognitive domain scores. A total of 362 patients were randomized to 3 to 12 mg/d rivastigmine capsules and 179 to placebo. Patients with PDD receiving rivastigmine improved versus placebo on items: word recall, following commands, ideational praxis, remembering test instructions, and comprehension of spoken language (P ADAS-cog is sensitive to broad cognitive changes in PDD. Overall, rivastigmine was associated with improvements on individual cognitive items and general cognitive domains.

  20. O6-methylguanine-DNA methyltransferase in wild-type and ada mutants of Escherichia coli

    International Nuclear Information System (INIS)

    Mitra, S.; Pal, B.C.; Foote, R.S.

    1982-01-01

    O 6 -Methylguanine-DNA methyltransferase is induced in Escherichia coli during growth in low levels of N-methyl-N'-nitro-N-nitrosoguanidine. We have developed a sensitive assay for quantitating low levels of this activity with a synthetic DNA substrate containing 3 H-labeled O 6 -methylguanine as the only modified base. Although both wild-type and adaptation-deficient (ada) mutants of E. coli contained low but comparable numbers (from 13 to 60) of the enzyme molecules per cell, adaptation treatment caused a significant increase of the enzyme in the wild type but not in the ada mutants, suggesting that the ada mutation is in a regulatory locus and not in the structural gene for the methyltransferase

  1. Court considers dentist's claim that ADA doesn't apply to HIV.

    Science.gov (United States)

    1996-11-29

    Oral arguments have begun in the 1st U.S. Circuit Court of Appeals in the case of dentist [name removed] who is charged with violating Title III of the Americans with Disabilities Act (ADA). [Name removed] refused to treat HIV-positive patient [name removed]. Ms. [Name removed] filed a complaint against [name removed] with the Maine Human Rights Commission. The ADA prohibits disability-based discrimination in public accommodations. A U.S. District judge in Maine rejected [name removed]'s argument that a patient with HIV infection poses a direct threat to a health care provider's health and safety. [Name removed] appealed, arguing that Abbot should not be entitled to ADA protection because reproduction is not a major life activity under the law. [Name removed] also argues that the standard universal precautions were not enough for him to feel secure. A decision in this case is expected in March 1997.

  2. Adult Autism Subthreshold Spectrum (AdAS Spectrum): Validation of a questionnaire investigating subthreshold autism spectrum.

    Science.gov (United States)

    Dell'Osso, L; Gesi, C; Massimetti, E; Cremone, I M; Barbuti, M; Maccariello, G; Moroni, I; Barlati, S; Castellini, G; Luciano, M; Bossini, L; Rocchetti, M; Signorelli, M; Aguglia, E; Fagiolini, A; Politi, P; Ricca, V; Vita, A; Carmassi, C; Maj, M

    2017-02-01

    Increasing literature has shown the usefulness of a dimensional approach to autism. The present study aimed to determine the psychometric properties of the Adult Autism Subthreshold Spectrum (AdAS Spectrum), a new questionnaire specifically tailored to assess subthreshold forms of autism spectrum disorder (ASD) in adulthood. 102 adults endorsing at least one DSM-5 symptom criterion for ASD (ASDc), 143 adults diagnosed with a feeding and eating disorder (FED), and 160 subjects with no mental disorders (CTL), were recruited from 7 Italian University Departments of Psychiatry and administered the following: SCID-5, Autism-Spectrum Quotient (AQ), Ritvo Autism and Asperger Diagnostic Scale 14-item version (RAADS-14), and AdAS Spectrum. The AdAS Spectrum demonstrated excellent internal consistency for the total score (Kuder-Richardson's coefficient=.964) as well as for five out of seven domains (all coefficients>.80) and sound test-retest reliability (ICC=.976). The total and domain AdAS Spectrum scores showed a moderate to strong (>.50) positive correlation with one another and with the AQ and RAADS-14 total scores. ASDc subjects reported significantly higher AdAS Spectrum total scores than both FED (pAdAS Spectrum scores from CTL subjects to ASD patients, across FED 0 , ASD 1 , FED 1 was shown. The AdAS Spectrum showed excellent internal consistency and test-retest reliability and strong convergent validity with alternative dimensional measures of ASD. The questionnaire performed differently among the three diagnostic groups and enlightened some significant effects of gender in the expression of autistic traits. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. [Is it pseudo-dementia? The validation of the Adas-Cog questionnaire in Hungary].

    Science.gov (United States)

    Drótos, Gergely; Pákáski, Magdolna; Papp, Edina; Kálmán, János

    2012-01-01

    The cognitive subscale of the Alzheimer's Disease Assessment Scale (ADAS-Cog) has been established internationally as an instrument for the assessment of treatment efficacy and cognitive performance in clinical trials. There is no data about the validity and characteristics of ADAS-Cog in Hungarian sample. This study is a part of the Hungarian standardization process of ADAS-Cog. It is crucial to examine the cognitive performance of patients with pseudodementia caused by depression (D) because of its' similarities with Alzheimer's disease (AK). The objective of the study was to analyze the characteristics of the cognitive subscale for further validation purposes. The study aimed at analyzing the ADAS-Cog performance of patients with D and AK in a Hungarian sample to make future studies more accurate through more exact differentiation between the two diseases. Fourty-seven normal elderly control (KNT) subjects, 66 AK patients and 39 patients with D participated in the study. The mental state and the severity of depressive symptoms of the participants were assessed by the means of ADAS-Cog, Mini Mental State Examination (MMSE) and Beck Depression Inventory. The ADAS-Cog is sensitive to the cognitive decline of the depressed group (sensitivity=69.2%, specificity=89.4%, AUC=0.868, p>0.001). While the performance of the two patient groups differed from the KNT, the groups are overlapping and the characteristic of the ROC curve and the optimal cut-off point (D:11.8; AK:12.1) indicates that the differentiation is mediocre. The results suggest that pseudodementia should be considered during the design of studies using ADASCog. Because the cognitive subscale can't accurately differentiate between AK and pseudodementia additional measures like BDI should be administered.

  4. Psychometric evaluation of ADAS-Cog and NTB for measuring drug response.

    Science.gov (United States)

    Karin, A; Hannesdottir, K; Jaeger, J; Annas, P; Segerdahl, M; Karlsson, P; Sjögren, N; von Rosen, T; Miller, F

    2014-02-01

    To conduct a psychometric analysis to determine the adequacy of instruments that measure cognition in Alzheimer's disease trials. Both the Alzheimer's Disease Assessment Scale - Cognition (ADAS-Cog) and the Neuropsychological Test Battery (NTB) are validated outcome measures for clinical trials in Alzheimer's disease and are approved also for regulatory purposes. However, it is not clear how comparable they are in measuring cognitive function. In fact, many recent trials in Alzheimer's disease patients have failed and it has been questioned if ADAS-Cog still is a sensitive measure. The present paper examines the psychometric properties of ADAS-Cog and NTB, based on a post hoc analysis of data from a clinical trial (NCT01024660), which was conducted by AstraZeneca, in mild-to-moderate Alzheimer's disease (AD) patients, with a Mini Mental State Examination (MMSE) Total score 16-24. Acceptability, reliability, different types of validity and ability to detect change were assessed using relevant statistical methods. Total scores of both tests, as well as separate domains of both tests, including the Wechsler Memory Scale (WMS), Rey Auditory Verbal Learning Test (RAVLT) and Delis-Kaplan Executive Function System (D-KEFS) Verbal Fluency Condition, were analyzed. Overall, NTB performed well, with acceptable reliability and ability to detect change, while ADAS-Cog had insufficient psychometric properties, including ceiling effects in 8 out of a total of 11 ADAS-Cog items in mild AD patients, as well as low test-retest reliability in some of the items. Based on a direct comparison on the same patient sample, we see advantages of the NTB compared with the ADAS-Cog for the evaluation of cognitive function in the population of mild-to-moderate AD patients. The results suggest that not all of ADAS-Cog items are relevant for both mild and moderate AD population. This validation study demonstrates satisfactory psychometric properties of the NTB, while ADAS-Cog was found to be

  5. Can pleural adenosine deaminase (ADA) levels in pleural tuberculosis predict the presence of pulmonary tuberculosis? A CT analysis

    International Nuclear Information System (INIS)

    Koh, Myung Je; Lee, In Jae; Kim, Joo-Hee

    2016-01-01

    Aim: To assess the relationship between imaging features of pulmonary tuberculosis at computed tomography (CT) and adenosine deaminase (ADA) values via pleural fluid analysis in patients with pleural tuberculosis. Materials and methods: This retrospective study enrolled 60 patients who underwent fluid analysis for ADA and chest CT and were diagnosed with tuberculosis by culture or polymerase chain reaction of pleural fluid and sputum. The presence of centrilobular nodules, consolidation, cavitation, and mediastinal lymphadenopathy at CT were evaluated. The relationship between ADA values and the pattern of pulmonary involvement of tuberculosis was analysed. Results: Pulmonary involvement was seen in 42 of the 60 patients. A centrilobular nodular pattern was seen in 37 and consolidation in 22. In 17 patients, both findings were identified. A centrilobular nodular pattern was more common than consolidation or cavitary lesions. When ADA values were high, pulmonary involvement was more frequent (p=0.002). Comparing low and high ADA groups using an obtained cut-off value of 80 IU/l, the high group had more frequent pulmonary involvement (p<0.001). Conclusion: Patients with tuberculous pleurisy who had high ADA values had a higher probability of manifesting pulmonary tuberculosis. High ADA values may help predict contagious pleuroparenchymal tuberculosis. The most common pulmonary involvement of tuberculous pleurisy showed a centrilobular nodular pattern. - Highlights: • To know the relationship of ADA values and pulmonary involvement pattern of pleural tuberculosis. • To help exact diagnosis of pleuroparenchymal tuberculosis in clinical setting. • The imaging findings of pleuroparenchymal tuberculosis.

  6. Lessons learned: Managing the development of a corporate Ada training project

    Science.gov (United States)

    Blackmon, Linda F.

    1986-01-01

    The management lessons learned during the implementation of a corporate mandate to develop and deliver an effective Ada training program to all divisions are discussed. The management process involved in obtaining cooperation from all levels in the development of a corporate-wide project is described. The problem areas are identified along with some possible solutions.

  7. Anemia nos pacientes com insuficiência cardíaca avançada

    Directory of Open Access Journals (Sweden)

    Juliano Cardoso

    2010-10-01

    Full Text Available FUNDAMENTO: Anemia está associada à pior evolução nos pacientes com insuficiência cardíaca (IC. Entretanto, há poucos estudos sobre a anemia nos pacientes com IC avançada. OBJETIVO: Avaliar as características da anemia na IC em fase avançada. MÉTODOS: Foram incluídos 99 pacientes hospitalizados para compensação de IC (CF IV/NYHA, com idade > 18 anos e FEVE 12 g/dl. A anemia foi marcador independente de mau prognóstico na análise multivariada (mortalidade 47% vs 24,6%, p = 0,016, risco relativo 2,54. CONCLUSÃO: Anemia acomete, aproximadamente, 1/3 dos pacientes com IC avançada, e a deficiência de ferro é uma importante etiologia. Pacientes anêmicos são mais idosos e apresentaram função renal mais deteriorada. A melhora da congestão não foi suficiente para melhorar a anemia na maioria dos casos. Nos pacientes com IC avançada, a anemia é marcador independente de mau prognóstico.

  8. Revising the ADAS-cog for a more accurate assessment of cognitive impairment

    NARCIS (Netherlands)

    Wouters, H.; van Gool, W.A.; Schmand, B.; Lindeboom, R.

    2008-01-01

    Background: To examine whether it is appropriate to sum the cognitive part of the Alzheimer Disease Assessment Scale (ADAS-cog) items to assess cognitive impairment. This assumes items to have (1) equal measurement precision and (2) hierarchically ordered categories. Methods: Rasch analysis on the

  9. How Do Scores on the ADAS-Cog, MMSE, and CDR-SOB Correspond?

    Science.gov (United States)

    Balsis, Steve; Benge, Jared F; Lowe, Deborah A; Geraci, Lisa; Doody, Rachelle S

    2015-01-01

    Clinicians and researchers who measure cognitive dysfunction often use the Alzheimer's Disease Assessment Scale--Cognitive Subscale (ADAS-Cog), the Mini-Mental State Examination (MMSE), or the Clinical Dementia Rating scale (CDR-SOB). But, the use of different measures can make it difficult to compare data across patients or studies. What is needed is a simple chart that shows how scores on these three important measures correspond to each other. Using data from 1709 participants from the Alzheimer's Disease Neuroimaging Initiative and item response theory-based statistics, we analyzed how scores on each measure, the ADAS-Cog, the MMSE, and the CDR-SOB, correspond. Results indicated multiple inflections in CDR-SOB and ADAS-Cog scores within a given MMSE score, suggesting that the CDR-SOB and ADAS-Cog are more precise in measuring the severity of cognitive dysfunction than the MMSE. This study shows how scores on these three popular measures of cognitive dysfunction correspond to each other, which is very useful information for both researchers and clinicians.

  10. 75 FR 54543 - Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles

    Science.gov (United States)

    2010-09-08

    ... ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD 36 CFR Part 1192 [Docket No. ATBCB 2010-0004] RIN 3014-AA38 Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles AGENCY: Architectural and Transportation Barriers Compliance Board. ACTION: Notice of public...

  11. 77 FR 56590 - Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles

    Science.gov (United States)

    2012-09-13

    ... ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD 36 CFR Part 1192 [Docket No. ATBCB 2010-0004] RIN 3014-AA38 Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles AGENCY: Architectural and Transportation Barriers Compliance Board. ACTION: Notice of information...

  12. 77 FR 50068 - Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles

    Science.gov (United States)

    2012-08-20

    ... ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD 36 CFR Part 1192 [Docket No. ATBCB 2010-0004] RIN 3014-AA38 Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles AGENCY: Architectural and Transportation Barriers Compliance Board. ACTION: Notice of public...

  13. Getting ADAS on the Road : Actors' Interactions in Advanced Driver Assistance Systems Deployment

    NARCIS (Netherlands)

    Walta, L.

    2011-01-01

    Currently, many car drivers spend many hours in congested traffic. If their cars would have been equipped with an electronic system that automatically follows the car in front of them, congestion might have been prevented. Such a system is an example of Advanced Driver Assistance Systems (ADAS).

  14. Analysis of the steel braced frames equipped with ADAS devices under the far field records

    Directory of Open Access Journals (Sweden)

    Mahmoud Bayat

    Full Text Available The usefulness of supplementary energy dissipation devices is now quite well-known in earthquake structural engineering for reducing the earthquake-induced response of structural systems. The seismic behavior of structures with supplemental ADAS devices is concerned in this study. In this paper, the ratio of the hysteretic energy to input energy is compared in different structural systems. The main purpose of this paper is to evaluate the behavior of structures equipped with yielding dampers (ADAS, located in far fields based on energy concepts. In order to optimize their seismic behavior, the codes and solutions are also presented. Three cases including five, ten and fifteen-story three-bay Concentric Braced Frames (CBF with and without ADAS were selected. The PERFORM 3D.V4 software along with three earthquake records (Northridge, Imperial Valley and Tabas is used for nonlinear time history analysis and the conclusions are drawn upon energy criterion. The effect of PGA variation and height of the frames are also considered in the study. Finally, to increase the energy damping ability and reduce the destructive effects in structures on an earthquake event, so that a great amount of induced energy is damped and destruction of the structure is prevented as much as possible by using ADAS dampers.

  15. Item analysis of ADAS-Cog: effect of baseline cognitive impairment in a clinical AD trial.

    Science.gov (United States)

    Sevigny, Jeffrey J; Peng, Yahong; Liu, Lian; Lines, Christopher R

    2010-03-01

    We explored the association of Alzheimer's disease (AD) Assessment Scale (ADAS-Cog) item scores with AD severity using cross-sectional and longitudinal data from the same study. Post hoc analyses were performed using placebo data from a 12-month trial of patients with mild-to-moderate AD (N =281 randomized, N =209 completed). Baseline distributions of ADAS-Cog item scores by Mini-Mental State Examination (MMSE) score and Clinical Dementia Rating (CDR) sum of boxes score (measures of dementia severity) were estimated using local and nonparametric regressions. Mixed-effect models were used to characterize ADAS-Cog item score changes over time by dementia severity (MMSE: mild =21-26, moderate =14-20; global CDR: mild =0.5-1, moderate =2). In the cross-sectional analysis of baseline ADAS-Cog item scores, orientation was the most sensitive item to differentiate patients across levels of cognitive impairment. Several items showed a ceiling effect, particularly in milder AD. In the longitudinal analysis of change scores over 12 months, orientation was the only item with noticeable decline (8%-10%) in mild AD. Most items showed modest declines (5%-20%) in moderate AD.

  16. Revising the ADAS-cog for a more accurate assessment of cognitive impairment

    NARCIS (Netherlands)

    Wouters, Hans; van Gool, Willem A; Schmand, Ben; Lindeboom, Robert

    2008-01-01

    BACKGROUND: To examine whether it is appropriate to sum the cognitive part of the Alzheimer Disease Assessment Scale (ADAS-cog) items to assess cognitive impairment. This assumes items to have (1) equal measurement precision and (2) hierarchically ordered categories. METHODS: Rasch analysis on the

  17. Reliability of the Alzheimer's disease assessment scale (ADAS-Cog) in longitudinal studies.

    Science.gov (United States)

    Khan, Anzalee; Yavorsky, Christian; DiClemente, Guillermo; Opler, Mark; Liechti, Stacy; Rothman, Brian; Jovic, Sofija

    2013-11-01

    Considering the scarcity of longitudinal assessments of reliability, there is need for a more precise understanding of cognitive decline in Alzheimer's Disease (AD). The primary goal was to assess longitudinal changes in inter-rater reliability, test retest reliability and internal consistency of scores of the ADAS-Cog. 2,618 AD subjects were enrolled in seven randomized, double-blind, placebo-controlled, multicenter-trials from 1986 to 2009. Reliability, internal-consistency and cross-sectional analysis of ADAS-Cog and MMSE across seven visits were examined. Intra-class correlation (ICC) for ADAS-Cog was moderate to high supporting their reliability. Absolute Agreement ICCs 0.392 (Visit-7) to 0.806 (Visit-2) showed a progressive decrease in correlations across time. Item analysis revealed a decrease in item correlations, with the lowest correlations for Visit 7 for Commands (ICC=0.148), Comprehension (ICC=0.092), Spoken Language (ICC=0.044). Suitable assessment of AD treatments is maintained through accurate measurement of clinically significant outcomes. Targeted rater education ADAS-Cog items over-time can improve ability to administer and score the scale.

  18. How well do the ADAS-cog and its subscales measure cognitive dysfunction in Alzheimer's disease?

    Science.gov (United States)

    Benge, Jared F; Balsis, Steve; Geraci, Lisa; Massman, Paul J; Doody, Rachelle S

    2009-01-01

    The Alzheimer's Disease Assessment Scale-cognitive (ADAS-cog) is regularly used to assess cognitive dysfunction in Alzheimer's disease (AD) clinical trials. Yet, little is known about how the instrument and its subscales measure cognition across the spectrum of AD. The current investigation used item response theory (IRT) analyses to assess the measurement properties of the ADAS-cog across the range of cognitive dysfunction in AD. We used IRT-based analyses to establish the relationship between cognitive dysfunction and the probability of obtaining observed scores on each subscale and the test as a whole. Data were obtained from 1,087 patients with AD and amnestic mild cognitive impairment. Results showed that the ADAS-cog and its subscales provide maximum information at moderate levels of cognitive dysfunction. Raw score differences toward the lower and higher ends of the scale corresponded to large differences in cognitive dysfunction, whereas raw score differences toward the middle of the scale corresponded to smaller differences. The utility of the ADAS-cog and its subscales is optimal in the moderate range of cognitive dysfunction, but raw score differences in that region correspond to relatively small differences in cognitive dysfunction. Implications for tracking and staging dementia and for clinical trials are discussed. Copyright 2009 S. Karger AG, Basel.

  19. OSHA and ADA: "Reasonable Accommodation" in Training Persons with Developmental Disabilities.

    Science.gov (United States)

    Sandoz, Charles J.

    This paper documents an approach to meeting the training requirements of the Occupational Safety and Health Act (OSHA) and the "reasonable accommodation" requirements of the Americans with Disabilities Act (ADA) for individuals with developmental disabilities. It describes a training program used with three adult workers with mild mental…

  20. EVALUATION OF THE ADA TECHNOLOGIES' ELECTRO-DECON PROCESS TO REMOVE RADIOLOGICAL CONTAMINATION

    Energy Technology Data Exchange (ETDEWEB)

    Pao, Jenn-Hai; Demmer, Rick L.; Argyle, Mark D.; Veatch, Brad D.

    2003-02-27

    A surface decontamination system featuring the use of ADA's electrochemical process was tested and evaluated. The process can be flexibly deployed by using an electrolyte delivery system that has been demonstrated to be reliable and effective. Experimental results demonstrate the effectiveness of this system for the surface decontamination of radiologically contaminated stainless steel.

  1. COMPARING THE EFFICACY OF ADA AND PCR IN DIAGNOSING TUBERCULOSIS IN PLEURAL EFFUSION

    Directory of Open Access Journals (Sweden)

    Prasanna Kumar T

    2017-05-01

    Full Text Available BACKGROUND Pleural effusion due to TB is currently the most common location for extrapulmonary TB and cases of pleural TB can be expected to increase with the increasing incidence of TB Worldwide. Historically, pleural biopsy was found to be more sensitive in diagnosing TB in pleural effusion as it is more invasive and hazardous than thoracocentesis, alternative diagnostic approaches have been extensively evaluated. Adenosine Deaminase (ADA has been developed and widely used for the diagnosis of TB due to its simplicity. The aim of the study is to assess and compare the validity of ADA and PCR by calculating the sensitivity and specificity in diagnosing tuberculosis among the patients with pleural effusion. MATERIALS AND METHODS A cross-sectional study was undertaken at our hospital for a period of 2 years between January 2014 to January 2016. 124 patients were admitted during that period and after getting the informed consent signed by the study population. They were included in our study. ADA activity was measured by the standard method as suggested by Guisti. Two mL of pleural fluid was collected in sterile container and was either immediately analysed or refrigerated at 4°C and analysed within 2 days. An ADA value >40 U/L was taken as the cutoff for calculating sensitivity and specificity. Polymerase chain reaction for M. tuberculosis 65 kDa gene was performed on pleural fluid specimens as previously described. The data were entered and analysed by using SPSS version 20. RESULTS Among 124 patients, 97 patients had been confirmed TB. So far, our analysis, we took 97 patients in which 79 were confirmed TB through HPE, 17 through pleural fluid culture and one patient was diagnosed by pleural fluid AFB smear. In our study, the ADA cutoff was assigned as 40 IU/L. The mean ADA levels among the patients with TB pleural effusion were found to be 53.5 IU/L. The sensitivity was 94%, whereas the specificity and the positive predictive value was found

  2. Alteration/Deficiency in Activation 3 (ADA3) Protein, a Cell Cycle Regulator, Associates with the Centromere through CENP-B and Regulates Chromosome Segregation*

    Science.gov (United States)

    Mohibi, Shakur; Srivastava, Shashank; Wang-France, Jun; Mirza, Sameer; Zhao, Xiangshan; Band, Hamid; Band, Vimla

    2015-01-01

    ADA3 (alteration/deficiency in activation 3) is a conserved component of several transcriptional co-activator and histone acetyltransferase (HAT) complexes. Recently, we generated Ada3 knock-out mice and demonstrated that deletion of Ada3 leads to early embryonic lethality. The use of Ada3FL/FL mouse embryonic fibroblasts with deletion of Ada3 using adenovirus Cre showed a critical role of ADA3 in cell cycle progression through mitosis. Here, we demonstrate an association of ADA3 with the higher order repeat region of the α-satellite region on human X chromosome centromeres that is consistent with its role in mitosis. Given the role of centromere proteins (CENPs) in mitosis, we next analyzed whether ADA3 associates with the centromere through CENPs. Both an in vivo proximity ligation assay and immunofluorescence studies confirmed the association of ADA3 with CENP-B protein, a highly conserved centromeric protein that binds to the 17-bp DNA sequences on α-satellite DNA. Deletional analysis showed that ADA3 directly associates with CENP-B through its N terminus, and a CENP-B binding-deficient mutant of ADA3 was incompetent in cell proliferation rescue. Notably, knockdown of ADA3 decreased binding of CENP-B onto the centromeres, suggesting that ADA3 is required for the loading of CENP-B onto the centromeres. Finally, we show that deletion of Ada3 from Ada3FL/FL mouse embryonic fibroblasts exhibited various chromosome segregation defects. Taken together, we demonstrate a novel ADA3 interaction with CENP-B-centromere that may account for its previously known function in mitosis. This study, together with its known function in maintaining genomic stability and its mislocalization in cancers, suggests an important role of ADA3 in mitosis. PMID:26429915

  3. Alteration/Deficiency in Activation 3 (ADA3) Protein, a Cell Cycle Regulator, Associates with the Centromere through CENP-B and Regulates Chromosome Segregation.

    Science.gov (United States)

    Mohibi, Shakur; Srivastava, Shashank; Wang-France, Jun; Mirza, Sameer; Zhao, Xiangshan; Band, Hamid; Band, Vimla

    2015-11-20

    ADA3 (alteration/deficiency in activation 3) is a conserved component of several transcriptional co-activator and histone acetyltransferase (HAT) complexes. Recently, we generated Ada3 knock-out mice and demonstrated that deletion of Ada3 leads to early embryonic lethality. The use of Ada3(FL/FL) mouse embryonic fibroblasts with deletion of Ada3 using adenovirus Cre showed a critical role of ADA3 in cell cycle progression through mitosis. Here, we demonstrate an association of ADA3 with the higher order repeat region of the α-satellite region on human X chromosome centromeres that is consistent with its role in mitosis. Given the role of centromere proteins (CENPs) in mitosis, we next analyzed whether ADA3 associates with the centromere through CENPs. Both an in vivo proximity ligation assay and immunofluorescence studies confirmed the association of ADA3 with CENP-B protein, a highly conserved centromeric protein that binds to the 17-bp DNA sequences on α-satellite DNA. Deletional analysis showed that ADA3 directly associates with CENP-B through its N terminus, and a CENP-B binding-deficient mutant of ADA3 was incompetent in cell proliferation rescue. Notably, knockdown of ADA3 decreased binding of CENP-B onto the centromeres, suggesting that ADA3 is required for the loading of CENP-B onto the centromeres. Finally, we show that deletion of Ada3 from Ada3(FL/FL) mouse embryonic fibroblasts exhibited various chromosome segregation defects. Taken together, we demonstrate a novel ADA3 interaction with CENP-B-centromere that may account for its previously known function in mitosis. This study, together with its known function in maintaining genomic stability and its mislocalization in cancers, suggests an important role of ADA3 in mitosis. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  4. A Novel AdaBoost Framework With Robust Threshold and Structural Optimization.

    Science.gov (United States)

    Zhang, Peng-Bo; Yang, Zhi-Xin

    2018-01-01

    The AdaBoost algorithm is a popular ensemble method that combines several weak learners to boost generalization performance. However, conventional AdaBoost.RT algorithms suffer from the limitation that the threshold value must be manually specified rather than chosen through a self-adaptive mechanism, which cannot guarantee a result in an optimal model for general cases. In this paper, we present a generic AdaBoost framework with robust threshold mechanism and structural optimization on regression problems. The error statistics of each weak learner on one given problem dataset is utilized to automate the choice of the optimal cut-off threshold value. In addition, a special single-layer neural network is employed to provide a second opportunity to further adjust the structure and strength the adaption capability of the AdaBoost regression model. Moreover, to consolidate the theoretical foundation of AdaBoost algorithms, we are the first to conduct a rigorous and comprehensive theoretical analysis on the proposed approach. We prove that the general bound on the empirical error with a fraction of training examples is always within a limited soft margin, which indicates that our novel algorithm can avoid over-fitting. We further analyze the bounds on the generalization error directly under probably approximately correct learning. The extensive experimental verifications on the UCI benchmarks have demonstrated that the performance of the proposed method is superior to other state-of-the-art ensemble and single learning algorithms. Furthermore, a real-world indoor positioning application has also revealed that the proposed method has higher positioning accuracy and faster speed.

  5. The ADAS-cog and clinically meaningful change in the VISTA clinical trial of galantamine for Alzheimer's disease.

    Science.gov (United States)

    Rockwood, Kenneth; Fay, Sherri; Gorman, Mary

    2010-02-01

    A minimum 4-point change at 6 months on the Alzheimer's disease assessment scale-cognitive subscale (ADAS-cog) is deemed clinically important, but this cut-point has been little studied in relation to clinical meaningfulness. In an investigator-initiated, clinical trial of galantamine, we investigated the extent to which a 4-point change classifies goal attainment by individual patients. Secondary analysis of the video imaging synthesis of treating Alzheimer's disease (VISTA) study: a 4-month, multi-centre, parallel-group, double-blind, placebo-controlled, trial of galantamine in 130 mild-moderate Alzheimer's disease patients (4-month open-label follow-up). ADAS-cog responses at 6 months were compared with outcomes on three clinical measures: clinician's interview based impression of change-plus caregiver input (CIBIC+), patient/carer-goal attainment scaling (PGAS) and clinician-GAS (CGAS). Thirty-seven of 99 patients improved by > or = 4 points on the ADAS-cog at 6 months, and 16/99 showed > or = 4-point worsening. ADAS-cog change scores correlated notionally to modestly with changes on the CGAS (r = -0.31), the PGAS (r = -0.29) and the CIBIC+ (r = 0.31). As a group, patients with ADAS-cog improvement were significantly more likely to improve on the clinical measures; those who worsened showed non-significant clinical decline. Individually, about half were misclassified in relation to each clinical measure; often when the ADAS-Cog detected 'no change', clinically meaningful effects could be detected. Even so, no ADAS-Cog cut-point optimally classified patients' clinical responses. A 4-point ADAS-cog change at 6 months is clinically meaningful for groups. Substantial individual misclassification between the ADAS-cog and clinical measures suggests no inherent meaning to a 4-point ADAS-cog change for a given patient.

  6. Detecting treatment effects with combinations of the ADAS-cog items in patients with mild and moderate Alzheimer's disease.

    Science.gov (United States)

    Ihl, Ralf; Ferris, Steven; Robert, Philippe; Winblad, Bengt; Gauthier, Serge; Tennigkeit, Frank

    2012-01-01

    When complex cognitive functions are measured with multi-item scales like the Alzheimer's Disease Assessment Scale - cognitive subscale (ADAS-cog), it seems valuable information can be lost due to combination of the ADAS-cog items results into a total score. We hypothesized, that an analysis of the results of different ADAS-cog item combinations may reveal drug treatment effects in distinct cognitive domains and/or enhance the sensitivity to detect such treatment effects. Here, we present a novel approach called 'subsetting analysis' for assessment of drug treatment effects with multi-item scales, like the ADAS-cog. The subsetting approach is a mathematical algorithm designed to select and group scale items in a subset detecting drug treatment effects in a particular study population. The approach was applied in a post-hoc analysis of ADAS-cog results from two randomized, placebo-controlled and double-blind clinical trials with memantine in mild to moderate Alzheimer's disease (AD). The subsetting analysis of the ADAS-cog combined database aimed at selecting the scale items showing no worsening at study end compared to baseline due to memantine treatment in mild AD (Mini-Mental State Examination (MMSE >19)) patients. Two ADAS-cog subsets were finally revealed by the analysis: a subset of five ADAS-cog items, identified as most sensitive to memantine effects in mild AD patients, and a subset of six ADAS-cog items shown to detect significant memantine effects in moderate AD patients. The subsetting approach of analyzing ADAS-cog data is a powerful alternative for gaining information about drug effects on cognitive performance in mild and moderate AD patients. Copyright © 2011 John Wiley & Sons, Ltd.

  7. Ada Compiler Validation Summary Report. Certificate Number: 891126I1. 10217, TeleSoft TeleGen2 Ada Development System for Hewlett-Packard 9000/370. Completion of On-Site Testing: 26 November 1989

    Science.gov (United States)

    1989-11-26

    ond dentf) by block number) TeleSoft, TeleGen2 Ada Development System, Version 1.4, Ottobrunn West Germany, Hewlett - Parkard 9000/370 under HP/UX 6.5...Report:TeleSoft, 26 Nov. 1989 to 26 Nov. 1990 TeleGen2 Ada Development Systems for Hewlett -Packard 9000’ 7 PLRFORMING’DRG. REPORT NUMBER /370 (Host...TeleSoft TeleGen2 Ada Develonpt- System for Hewlett -Packard 90no/70 Completion of On-Site Testing: 26 November 1989 Prepared y: ZABG nbH, A-bt. SZT

  8. Long-term changes in ADAS-cog: what is clinically relevant for disease modifying trials in Alzheimer?

    Science.gov (United States)

    Vellas, B; Andrieu, S; Cantet, C; Dartigues, J F; Gauthier, S

    2007-01-01

    With the development of long-term disease modifying trials, changes in ADAS-Cog at 18 months will rise certainly many questions. We decided to look in the Real.fr study at the links between changes in cognition, ADAS-Cog and function. A total of 346 Alzheimer's patients with ADAS-cog at entry and at 18 months. were eligible for this analysis. These patients were on average 77.44 years old and 254 (72.36%) were women. The great majority lived at home and about 93% were treated with a cholinesterase inhibitor at baseline. Thirty three patients (9%) had a gain of more than 2 points at the ADAS-cog at 18 months (Group I, improvement); 130 (38%) were considered as stable, the reference group (Group II ) characterized by a stability at the ADAS-cog: decline of 2 points to gain of 2 points, 112 subjects (32%) had a moderate decline between 2 and 7 at the ADAScog (Group III) and finally 71 subjects (21%) had a severe impairment more than seven points at the ADAS-cog. A loss of one Basic ADL is certainly highly relevant, and such a change was found at 18 months in more than half of the subjects, which is not surprising for a long-term evolution in mild to moderate AD. An impairment of more than 7 points at the ADAS-cog was found in 21% of the subjects at 18 months and was associated with loss.

  9. A study of the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) in an Icelandic elderly population.

    Science.gov (United States)

    Hannesdóttir, Kristin; Snaedal, Jón

    2002-01-01

    The Alzheimer's Disease Assessment Scale (ADAS) is designed for screening of cognitive and non-cognitive dysfunctions characteristic of persons with probable Alzheimer's disease (AD). The cognitive part of the scale (ADAS-Cog) is both convenient for screening of probable AD and as a measure of cognitive functioning during drug intervention. The aim of this study was to translate the ADAS-Cognitive sub-test (ADAS-Cog) into Icelandic and to study its application in an elderly Icelandic population. The Mini-Mental State Examination (MMSE) and the ADAS-Cog were administered to 20 AD patients and 20 controls. Each patient was also rated on the Global Deterioration Scale (GDS). The probable AD patients were divided into two groups based on their GDS: 3-4 and 5-6 points. The patients were also divided into two groups based on their MMSE score: very mild to mild (23-30 points) and mild to moderate (15-22 points). Furthermore, the subjects were divided into two age groups: 65-76 and 77-92 years. Results revealed a highly significant difference on MMSE (22.3 +/- 3.4; 26.8 +/- 1.6; P ADAS-Cog (18.4 +/- 7.7; 7.3 +/- 3.5; P ADAS-Cog plays an important role in the diagnostic makeup of AD along with other detailed investigations, such as neuropsychological assessment.

  10. Discrimination of Breast Tumors in Ultrasonic Images by Classifier Ensemble Trained with AdaBoost

    Science.gov (United States)

    Takemura, Atsushi; Shimizu, Akinobu; Hamamoto, Kazuhiko

    In this paper, we propose a novel method for acurate automated discrimination of breast tumors (carcinoma, fibroadenoma, and cyst). We defined 199 features related to diagnositic observations noticed when a doctor judges breast tumors, such as internal echo, shape, and boundary echo. These features included novel features based on a parameter of log-compressed K distribution, which reflect physical characteristics of ultrasonic B-mode imaging. Furthermore, we propose a discrimination method of breast tumors by using an ensemble classifier based on the multi-class AdaBoost algorithm with effective features selection. Verification by analyzing 200 carcinomas, 30 fibroadenomas and 30 cycts showed the usefulness of the newly defined features and the effectiveness of the discrimination by using an ensemble classifier trained by AdaBoost.

  11. Real-time multi-camera video acquisition and processing platform for ADAS

    Science.gov (United States)

    Saponara, Sergio

    2016-04-01

    The paper presents the design of a real-time and low-cost embedded system for image acquisition and processing in Advanced Driver Assisted Systems (ADAS). The system adopts a multi-camera architecture to provide a panoramic view of the objects surrounding the vehicle. Fish-eye lenses are used to achieve a large Field of View (FOV). Since they introduce radial distortion of the images projected on the sensors, a real-time algorithm for their correction is also implemented in a pre-processor. An FPGA-based hardware implementation, re-using IP macrocells for several ADAS algorithms, allows for real-time processing of input streams from VGA automotive CMOS cameras.

  12. VIII Olimpíada Brasileira de Astronomia e Astronáutica

    Science.gov (United States)

    Garcia Canalle, João Batista; Villas da Rocha, Jaime Fernando; Wuensche de Souza, Carlos Alexandre; Pereira Ortiz, Roberto; Aguilera, Nuricel Villalonga; Padilha, Maria De Fátima Catta Preta; Pessoa Filho, José Bezerra; Soares Rodrigues, Ivette Maria

    2007-07-01

    Neste trabalho apresentamos as motivações pelas quais organizamos, em conjunto, pela primeira vez, a Olimpíada Brasileira de Astronomia incluindo a Astronáutica, em colaboração com a Agência Espacial Brasileira. Esta ampliação contribuiu para atrair ainda mais alunos, professores, escolas e patrocinadores para participarem desta Olimpíada. Em 2005 participaram da VIII Olimpíada Brasileira de Astronomia e Astronáutica (VIII OBA) 187.726 alunos distribuídos por 3.229 escolas, pertencentes a todos os estados brasileiros, incluindo o Distrito Federal. O crescimento em número de alunos participantes foi 52,4% maior do que em 2004. Em abril de 2005 organizamos, em Itapecerica da Serra, SP, um curso para os 50 alunos previamente selecionados e participantes da VII OBA e ao final selecionamos, dentre eles, uma equipe de 5 alunos, os quais representaram o Brasil na X Olimpíada Internacional de Astronomia, na China, em outubro de 2005. Ganhamos, pela primeira vez, uma medalha de ouro naquele evento. Em Agosto de 2005, organizamos a VIII Escola de Agosto para 50 alunos e respectivos professores, em Águas de Lindóia, SP, juntamente com a XXXI reunião anual da Sociedade Astronômica Brasileira (SAB). Em novembro de 2005 realizamos a I Jornada Espacial, em São José dos Campos, com 22 alunos e 22 professores selecionados dentre os participantes que melhores resultados obtiveram nas questões de Astronáutica da VIII OBA. Neste trabalho detalhamos os resultados da VIII OBA bem como as ações subseqüentes.

  13. Ada Savin, ed. Migration and Exile: Charting New Literary and Artistic Territories.

    OpenAIRE

    Diamantoulis, Anna

    2014-01-01

    This collection of essays entitled Migration and Exile: Charting New Literary and Artistic Territories and edited by Ada Savin aims to bring together essays whose central concerns, as indeed the title suggests, are migration and exile and whose engagement with these concerns raises questions regarding nation, memory, space and language, all of which are categorised as “the central components of the exiled writers’ and artists’ existence and creation” (2). This collection also prides itself in...

  14. Ada/APSE: A Successor to CORAL 66 in the 80’s,

    Science.gov (United States)

    1983-01-01

    in sufficient detail to do the language justice. Neither can it fully describe the APSE. da is defined in the da Language Reference Manual (LM) [3...interface and primitives are embodied in the Kernal APSE ( CAPSE ); secondly, a basic but useful set of ccopetent tools, which exploit the facilities...Cputer Programming Language CORAL66, BS5905, November 1980. [3] Reference Manual for the Ada Programming Language, US DDD, July 1982. [4] Requirements

  15. A portable generic elementary function package in Ada and an accurate test suite

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Ping Tak Peter.

    1990-11-01

    A comprehensive set of elementary functions has been implemented portably in Ada. The high accuracy of the implementation has been confirmed by rigorous analysis. Moreover, we present new test methods that are efficient and offer a high resolution of 0.005 unit in the last place. These test methods have been implemented portably here and confirm the accuracy of our implemented functions. Reports on the accuracy of other function libraries obtained by our test programs are also presented. 26 refs., 9 tabs.

  16. AdaFF: Adaptive Failure-Handling Framework for Composite Web Services

    Science.gov (United States)

    Kim, Yuna; Lee, Wan Yeon; Kim, Kyong Hoon; Kim, Jong

    In this paper, we propose a novel Web service composition framework which dynamically accommodates various failure recovery requirements. In the proposed framework called Adaptive Failure-handling Framework (AdaFF), failure-handling submodules are prepared during the design of a composite service, and some of them are systematically selected and automatically combined with the composite Web service at service instantiation in accordance with the requirement of individual users. In contrast, existing frameworks cannot adapt the failure-handling behaviors to user's requirements. AdaFF rapidly delivers a composite service supporting the requirement-matched failure handling without manual development, and contributes to a flexible composite Web service design in that service architects never care about failure handling or variable requirements of users. For proof of concept, we implement a prototype system of the AdaFF, which automatically generates a composite service instance with Web Services Business Process Execution Language (WS-BPEL) according to the users' requirement specified in XML format and executes the generated instance on the ActiveBPEL engine.

  17. Using Ada to implement the operations management system in a community of experts

    Science.gov (United States)

    Frank, M. S.

    1986-01-01

    An architecture is described for the Space Station Operations Management System (OMS), consisting of a distributed expert system framework implemented in Ada. The motivation for such a scheme is based on the desire to integrate the very diverse elements of the OMS while taking maximum advantage of knowledge based systems technology. Part of the foundation of an Ada based distributed expert system was accomplished in the form of a proof of concept prototype for the KNOMES project (Knowledge-based Maintenance Expert System). This prototype successfully used concurrently active experts to accomplish monitoring and diagnosis for the Remote Manipulator System. The basic concept of this software architecture is named ACTORS for Ada Cognitive Task ORganization Scheme. It is when one considers the overall problem of integrating all of the OMS elements into a cooperative system that the AI solution stands out. By utilizing a distributed knowledge based system as the framework for OMS, it is possible to integrate those components which need to share information in an intelligent manner.

  18. Software engineering and Ada (Trademark) training: An implementation model for NASA

    Science.gov (United States)

    Legrand, Sue; Freedman, Glenn

    1988-01-01

    The choice of Ada for software engineering for projects such as the Space Station has resulted in government and industrial groups considering training programs that help workers become familiar with both a software culture and the intricacies of a new computer language. The questions of how much time it takes to learn software engineering with Ada, how much an organization should invest in such training, and how the training should be structured are considered. Software engineering is an emerging, dynamic discipline. It is defined by the author as the establishment and application of sound engineering environments, tools, methods, models, principles, and concepts combined with appropriate standards, guidelines, and practices to support computing which is correct, modifiable, reliable and safe, efficient, and understandable throughout the life cycle of the application. Neither the training programs needed, nor the content of such programs, have been well established. This study addresses the requirements for training for NASA personnel and recommends an implementation plan. A curriculum and a means of delivery are recommended. It is further suggested that a knowledgeable programmer may be able to learn Ada in 5 days, but that it takes 6 to 9 months to evolve into a software engineer who uses the language correctly and effectively. The curriculum and implementation plan can be adapted for each NASA Center according to the needs dictated by each project.

  19. Inhibition of the SOS response of Escherichia coli by the Ada protein

    International Nuclear Information System (INIS)

    Vericat, J.A.; Guerrero, R.; Barbe, J.

    1988-01-01

    Induction of the adaptive response by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) caused a decrease in the UV-mediated expression of both recA and sfiA genes but not of the umuDC gene. On the other hand, the adaptive response did not affect the temperature-promoted induction of SOS response in a RecA441 mutant. The inhibitory effect on the UV-triggered expression of the recA and sfiA genes was not dependent on either the alkA gene or the basal level of RecA protein, but rather required the ada gene. Furthermore, an increase in the level of the Ada protein, caused by the runaway plasmid pYN3059 in which the ada gene is regulated by the lac promoter, inhibited UV-mediated recA gene expression even in cells to which the MNNG-adaptive treatment had not been applied. This inhibitory effect of the adaptive pretreatment was not observed either in RecBC- strains or in RecBC mutants lacking exonuclease V-related nuclease activity. However, RecF- mutants showed an adaptive response-mediated decrease in UV-promoted induction of the recA gene

  20. Novel vehicle detection system based on stacked DoG kernel and AdaBoost

    Science.gov (United States)

    Kang, Hyun Ho; Lee, Seo Won; You, Sung Hyun

    2018-01-01

    This paper proposes a novel vehicle detection system that can overcome some limitations of typical vehicle detection systems using AdaBoost-based methods. The performance of the AdaBoost-based vehicle detection system is dependent on its training data. Thus, its performance decreases when the shape of a target differs from its training data, or the pattern of a preceding vehicle is not visible in the image due to the light conditions. A stacked Difference of Gaussian (DoG)–based feature extraction algorithm is proposed to address this issue by recognizing common characteristics, such as the shadow and rear wheels beneath vehicles—of vehicles under various conditions. The common characteristics of vehicles are extracted by applying the stacked DoG shaped kernel obtained from the 3D plot of an image through a convolution method and investigating only certain regions that have a similar patterns. A new vehicle detection system is constructed by combining the novel stacked DoG feature extraction algorithm with the AdaBoost method. Experiments are provided to demonstrate the effectiveness of the proposed vehicle detection system under different conditions. PMID:29513727

  1. Hiring discrimination against people with disabilities under the ADA: characteristics of charging parties.

    Science.gov (United States)

    McMahon, Brian T; Roessler, Richard; Rumrill, Philip D; Hurley, Jessica E; West, Steven L; Chan, Fong; Carlson, Linnea

    2008-06-01

    This article describes findings from a causal comparative study of the characteristics of Charging Parties who filed allegations of Hiring discrimination with the U.S. Equal Employment Opportunity Commission (EEOC) under Title I of the Americans with Disabilities Act (ADA) between 1992 and 2005. Charging Party Characteristics derived from 19,527 closed Hiring allegations are compared and contrasted to 259,680 closed allegations aggregated from six other prevalent forms of discrimination including Discharge and Constructive Discharge, Reasonable Accommodation, Disability Harassment and Intimidation, and Terms and Conditions of Employment. Tests of Proportion distributed as chi-square are used to form comparisons along a variety of factors including age, gender, impairment, and ethnicity. Most allegations of ADA job discrimination fall into the realm of job retention and career advancement as opposed to job acquisition. Hiring allegations, however, tend to be filed by Charging Parties who are disproportionately male, younger or older applicants, white, and coping with physical or sensory disabilities. Prevailing theories about stigma suggest that negative attitudes are more prevalent toward persons with behavioral disabilities. However, this study provides clear evidence that one behavioral manifestation of negative attitudes, Hiring discrimination, is more often directed at persons with physical or sensory impairments. More outreach regarding ADA rights appears indicated for individuals who share the aforementioned characteristics.

  2. Study on the clinical value of determination of serum adenosine deaminase (ADA) and HA, PIIIP levels for diagnosis of chronic hepatitis

    International Nuclear Information System (INIS)

    Ma Yun

    2007-01-01

    Objective: To explore the clinical value of determination of serum ADA and HA, PIIIP levels for diagnosis of chronic hepatitis. Methods: Serum ADA levels were determined with biochemistry and HA, PIIIP levels were detected with RIA in 36 patients with chronic hepatitis and 35 controls. Results: The levels of serum ADA, HA and PIIIP were significantly higher in the patients than those in controls (P<0.01). Serum ADA, HA, PIIIP levelers were mutually positively correlated (r=0.6117, 0.7134, P<0.01). Conclusion: Detection of serum ADA levels could reflect the liver reserve function and status of fibrosis. (authors)

  3. Autologous transplants of Adipose-Derived Adult Stromal (ADAS) afford dopaminergic neuroprotection in a model of Parkinson’s disease

    OpenAIRE

    McCoy, Melissa K.; Martinez, Terina N.; Ruhn, Kelly A.; Wrage, Philip C.; Keefer, Edward W.; Botterman, Barry R.; Tansey, Keith E.; Tansey, Malú G.

    2007-01-01

    Adult adipose contains stromal progenitor cells with neurogenic potential. However, the stability of neuronal phenotypes adopted by Adipose-Derived Adult Stromal (ADAS) cells and whether terminal neuronal differentiation is required for their consideration as alternatives in cell replacement strategies to treat neurological disorders is largely unknown. We investigated whether in vitro neural induction of ADAS cells determined their ability to neuroprotect or restore function in a lesioned do...

  4. Annual ASEET (Ada Software Engineering Education and Training) Symposium (SLIDES) Held in Dallas, TX. on 9-11 June 1987.

    Science.gov (United States)

    1987-06-11

    University of New Orleans (UNO) started implementing the programming language Ada as the departamental language. This paper is a personal report of this 3...year effort. 0 .?.’. ? Structure of lecture. University Setting. 0 Departamental Setting Curriculum overview. Ada as a Primary Programming Language...third course no more than a 25% . attrition rate when Pascal was the departamental programming language. Many students drop the class due to the fact

  5. Biochemical detection of E-ADA on Neospora caninum tachyzoites and the effects of a specific enzymatic inhibitor

    Directory of Open Access Journals (Sweden)

    Alexandre A. Tonin

    2015-01-01

    Full Text Available Objective. This study aimed to investigate the presence and activity of the ecto adenosine deaminase (E-ADA enzyme in tachyzoites of Neospora caninum (Nc-1 strain, as well as to assess the activity of a well-known E-ADA inhibitor, the deoxycoformycin. Materials and methods. The parasites were grown in cell culture, being subsequently separated in a pellet of tachyzoites, on which the E-ADA activity was tested using the concentrations 0 (control, 0.2, 0.4 and 0.8 mg mL-1. Results. The E-ADA showed high activity, progressively increasing its activity according to the enhancement of the protein concentration. The test was carried out with different concentrations of deoxycoformycin, showing that it was able to inhibit the E-ADA present on the free form of the parasite. Conclusions. Based on these results we conclude that the E-ADA is present on tachyzoites of N. caninum, and deoxycoformycin is able to inhibit this enzyme. In this sense, knowing the negative impact of N. caninum on reproductive issue in cattle (mainly abortion, might it is an alternative in order to deal with this parasitic infection.

  6. Eustacio y el Proemio de sus Comentarios a la Ilíada

    Directory of Open Access Journals (Sweden)

    Lucia Adriana Liñares

    1999-12-01

    Full Text Available No Prólogo de seus Comentários à Ilíada, Eustácio faz referência aos valores essenciais da poesia homérica, e, também, a algumas questões abordadas pela crítica. O presente trabalho procura delimitar e definir a orientação interpretativa que manifesta o prólogo de Eustácio, a partir da análise das referências que o texto oferece.

  7. An Ada Linear-Algebra Software Package Modeled After HAL/S

    Science.gov (United States)

    Klumpp, Allan R.; Lawson, Charles L.

    1990-01-01

    New avionics software written more easily. Software package extends Ada programming language to include linear-algebra capabilities similar to those of HAL/S programming language. Designed for such avionics applications as Space Station flight software. In addition to built-in functions of HAL/S, package incorporates quaternion functions used in Space Shuttle and Galileo projects and routines from LINPAK solving systems of equations involving general square matrices. Contains two generic programs: one for floating-point computations and one for integer computations. Written on IBM/AT personal computer running under PC DOS, v.3.1.

  8. Rituais escolares: notas sobre jogos e olimpíadas escolares como rituais

    OpenAIRE

    Medeiros,Ana Gabriela Alves; Rios,Fernanda Gonçalves; Varnier,Thaíse Ramos; Ribeiro,Etyelle; Tavares,Otávio

    2012-01-01

    A teoria sociológica aponta que todas as sociedades constroem formas de celebração de seus valores e identidade. Segundo autores como DaCosta (2000) e MacAloon (1984), os jogos olímpicos pautam-se em valores da modernidade ocidental, e que os celebra em grandiosas cerimônias. Inseridos no âmbito escolar, identificamos um elevado número de "jogos" e/ou "olimpíadas" que, direta ou indiretamente, baseiam-se no modelo olímpico. Neste contexto, tivemos por objetivo analisar os sentidos, significad...

  9. Development of Ada language control software for the NASA power management and distribution test bed

    Science.gov (United States)

    Wright, Ted; Mackin, Michael; Gantose, Dave

    1989-01-01

    The Ada language software developed to control the NASA Lewis Research Center's Power Management and Distribution testbed is described. The testbed is a reduced-scale prototype of the electric power system to be used on space station Freedom. It is designed to develop and test hardware and software for a 20-kHz power distribution system. The distributed, multiprocessor, testbed control system has an easy-to-use operator interface with an understandable English-text format. A simple interface for algorithm writers that uses the same commands as the operator interface is provided, encouraging interactive exploration of the system.

  10. Argamassa Reforçada com Armadura Difusa de Aço

    Directory of Open Access Journals (Sweden)

    José Eduardo Fairbanks Nascimbeni

    1990-12-01

    Full Text Available Apresenta métodos de ensaio, resultados e conclusões de experimentos controlados em corpos de prova e peças de argamassa reforçada com fibras de aço, como armadura difusa, São abordadas considerações teóricas sobre as condições gerais de ruptura e sobre as interferências fibra/matriz. Concluiu-se haver viabilidade técnica no uso do compósito, quanto à resistência à flexão

  11. Resultados do Grupo de Trabalho de Tecnologias Avançadas IDE do Projecto OTALEX C

    OpenAIRE

    Vivas, Pedro; Álvarez, Rafael; Mateus, Júlio; Pavo, Marcos; Rubio, J.M.; González, Julián; Soriano, Marcos; Caballero, Carmen; Aparício, Alberto; Batista, T.; Carriço, Cristina; Cabezas, José; Fernández, Luis; Jiménez, Alberto; Gamero, Ulises

    2013-01-01

    Apresentam-se os resultado do Grupo de Trabalho de Tecnologias Avançadas IDE do projeto OTALEX-C, sendo estes: a geração de dados interligados de elementos geográficos do território OTALEX-C para a publicação de uma Web Semântica, e a captura e publicação de dados ambientais através de serviços padronizados de registo de observações com recurso a sensores, aplicando a standard SOS definida pela OGC. POCTEP 2007-2013

  12. Plaque removal efficacy of a prototype manual toothbrush versus an ADA reference manual toothbrush with and without dental floss.

    Science.gov (United States)

    Terezhalmy, Geza T; Bsoul, Samer A; Bartizek, Robert D; Biesbrock, Aaron R

    2005-08-15

    The objective of this study was to compare the plaque removal efficacy of a prototype manual Deep Clean toothbrush versus an American Dental Association (ADA) manual toothbrush and the ADA manual toothbrush in conjunction with floss. This study was a randomized, examiner-blind, six-period cross-over, single-center study conducted in 60 adult subjects that examined plaque removal with a prototype Deep Clean manual toothbrush, an ADA reference manual toothbrush, and an ADA reference manual toothbrush followed by floss. During the course of this study, subjects used each treatment two times. Plaque was scored before and after brushing using the Rustogi Modification of the Navy Plaque Index. A mixed model analysis of covariance (ANCOVA) for a crossover design with baseline plaque score as the covariate was applied to the baseline minus one-minute post-brushing differences in average whole-mouth plaque scores. Supplemental analyses were also performed using the ANCOVA model separately for average gingival margin scores and for average interproximal scores, using the appropriate baseline score as the covariate. All comparisons were two-sided at the 0.05 level of significance. The prototype Deep Clean manual toothbrush delivered an adjusted (via ANCOVA) mean difference between baseline and post-brushing plaque scores of 0.245, while the ADA manual toothbrush plus floss delivered an adjusted mean difference of 0.207 versus 0.196 for the ADA manual toothbrush alone. The prototype Deep Clean manual toothbrush demonstrated a statistically significantly greater reduction in plaque than the ADA manual toothbrush plus floss (pfloss groups, respectively. Results for the interproximal and gingival margin regions also demonstrated statistically significantly (pfloss group.

  13. Twenty-Five Years After the ADA: Situating Disability in America’s System of Stratification

    Directory of Open Access Journals (Sweden)

    Michelle Maroto

    2015-09-01

    Full Text Available Americans with disabilities represent a significant proportion of the population. Despite their numbers and the economic hardships they face, disability is often excluded from general sociological studies of stratification and inequality. To address some of these omissions, this paper focuses on employment and earnings inequality by disability status in the United States since the enactment of the 1990 Americans with Disabilities Act (ADA, a policy that affects many Americans. After using Current Population Survey data from 1988-2014 to describe these continuing disparities, we review research that incorporates multiple theories to explain continuing gaps in employment and earnings by disability status. In addition to theories pointing to the so-called failures of the ADA, explanations also include general criticisms of the capitalist system and economic downturns, dependence on social welfare and disability benefits, the nature of work, and employer attitudes. We conclude with a call for additional research on disability and discrimination that helps to better situate disability within the American stratification system.

  14. Computer-aided detection of polyps in CT colonography by means of AdaBoost

    Science.gov (United States)

    Xu, Jian-Wu; Suzuki, Kenji

    2012-03-01

    Computer-aided detection (CADe) has been investigated for assisting radiologists in detecting polyps in CT colonography (CTC). One of the major challenges in current CADe of polyps in CTC is to improve the specificity without sacrificing the sensitivity. We have developed several CADe schemes based on a massive-training framework with different nonlinear regression models such as neural network regression, support vector regression, and Gaussian process regression. Individual CADe schemes based on different nonlinear regression models, however, achieved comparable results. In this paper, we propose to use the AdaBoost algorithm to combine different regression models in CADe schemes for improving the specificity without sacrificing the sensitivity. To test the performance of the proposed approach, we compared it with individual regression models in the distinction between polyps and various types of false positives (FPs). Our CTC database consisted of 246 CTC datasets obtained from 123 patients in the supine and prone positions. The testing set contained 93 patients including 19 polyps in seven patients and 86 negative patients with 474 FPs produced by an original CADe scheme. The AdaBoost algorithm combining multiple massive-training regression models achieved a performance that was higher than each individual regression model, yielding a 94.7% (18/19) bypolyp sensitivity at an FP rate of 2.0 (188/93) per patient in a leave-one-lesion-out cross validation test.

  15. ADA1 and NET1 Genes of Yeast Mediate Both Chromosome Maintenance and Mitochondrial $\\rho^{-}$ Mutagenesis

    CERN Document Server

    Koltovaya, N A; Tchekhouta, I A; Devin, A B

    2002-01-01

    An increase in the mitochondrial (mt) rho^- mutagenesis is a well-known respose of yeast cells to mutations in the numerous nuclear genes as well as to various kinds of stress. Notwithstanding the extensive studies during several decades the biological significance of this response is not yet fully understood. The genetic approach to solution of this subject includes the study of genes that are required for the high incidence of spontaneous rho^- mutants. Previously we found that mutations in certain nuclear genes including CDC28, the central cell-cycle regulation gene, may decrease the spontaneous rho^- mutability and simultaneously affect maintenance of the yeast chromosomes and plasmids. The present work provides data on identification of two more genes, resembling CDC28 in this respect. These genes NET1 and ADA1 mediate important regulatory protein-protein interactions in the yeast cell. The effects of net1 and ada1 mutations on the maintenance of yeast mt genome, chromosomes and plasmids as well as on ce...

  16. Failure to prove procreation is a life function dooms ADA suit.

    Science.gov (United States)

    1999-11-26

    The U.S. District Court for the Northern District of Texas rejected arguments in a discrimination case filed by [name removed], who sued American Airlines for discrimination following his dismissal in 1997. The court ruled that the plaintiff failed to prove that his HIV infection substantially limited him in any life functions covered under the Americans with Disabilities Act. [Name removed], who cited his inability to reproduce because of his infection, admitted in a deposition that he never had a desire to father children. The court held that his decision was a personal one, not subject to ADA limitations. The Equal Employment Opportunity Commission (EEOC) came to the same decision in the case, saying that [name removed] was not limited in his ability to walk, hear, see, breathe, or care for himself in any way. The ruling is the second of its kind. In the first case, [name removed] v. [Name removed]'s Stores Inc., the judge ruled that sexual intercourse was not a major life activity under the ADA meaning.

  17. Rivastigmine in Alzheimer's disease and Parkinson's disease dementia: an ADAS-cog factor analysis.

    Science.gov (United States)

    Weintraub, Daniel; Somogyi, Monique; Meng, Xiangyi

    2011-09-01

    Rivastigmine treatment is associated with significant improvements on the cognitive subscale of the Alzheimer's Disease Assessment Scale (ADAS-cog) in patients with mild-to-moderate Alzheimer's disease (AD) and Parkinson's disease dementia (PDD). Both AD and PDD are purported to have different profiles of cognitive impairment, which may respond differentially to rivastigmine treatment. This was a retrospective analysis of 3 randomized, double-blind, rivastigmine trial databases (Investigation of transDermal Exelon in ALzheimer's disease [IDEAL; AD], EXelon in PaRkinson's disEaSe dementia Study [EXPRESS; PDD], and Alzheimer's Disease with ENA 713 [ADENA; AD]). Factor analyses of the 11 baseline ADAS-cog items derived the same factors in the 2 diseases, that is, "memory" and "language". Rivastigmine-treated AD and PDD patients showed significant improvements (P < .0001 versus placebo) on both factors. For both AD and PDD, rivastigmine had a numerically greater effect on memory than language. Treatment effect sizes were numerically greater in PDD compared with AD. Rivastigmine treatment is associated with improvement in memory and language in AD and PDD. The numerically greater response in PDD is consistent with greater cholinergic deficits in this disease state.

  18. A Logic Architecture for 360 ADAS-Alerts for Hazards Detection Based in Driver Actions

    Directory of Open Access Journals (Sweden)

    Izquierdo-Reyes Javier

    2017-01-01

    Full Text Available In this work is presented a novel approach for passive safety in vehicles by Advanced Driver Assistance Systems (ADAS alert emission in 360° around driver to notify about hazards nearby the vehicle depending on the actions taken by driver per the context. This proposal would create a more robust system compared to current passive ADAS systems since the feedback to driver is in the same direction that hazard is detected (Punctual Sound Source Alert, compared with most assistance systems that emits sounds from the monitor or from the dashboard provoking distractions when emits alerts unnecessarily. The increase of security by this method will allow the driver to be aware of their surroundings even in a very quiet cabin or in a noisy environment. Also, it would detect the steering wheel angle, speed of movement and the activation of turning lights among other alerts, which would allow us to define a critical action during driving; apart from using sensors and cameras aimed at the driver to detect patterns of movement during these critical actions and have a prediction of a possible turn or manoeuvre when driving, refer to Figure 1. It will be necessary a reconfiguration of the alert in frequency, time of action depending upon the level of risk to prevent an accident or to reduce the consequences in an imminent accident.

  19. Functional ADA polymorphism increases sleep depth and reduces vigilant attention in humans.

    Science.gov (United States)

    Bachmann, Valérie; Klaus, Federica; Bodenmann, Sereina; Schäfer, Nikolaus; Brugger, Peter; Huber, Susanne; Berger, Wolfgang; Landolt, Hans-Peter

    2012-04-01

    Homeostatically regulated slow-wave oscillations in non-rapid eye movement (REM) sleep may reflect synaptic changes across the sleep-wake continuum and the restorative function of sleep. The nonsynonymous c.22G>A polymorphism (rs73598374) of adenosine deaminase (ADA) reduces the conversion of adenosine to inosine and predicts baseline differences in sleep slow-wave oscillations. We hypothesized that this polymorphism affects cognitive functions, and investigated whether it modulates electroencephalogram (EEG), behavioral, subjective, and biochemical responses to sleep deprivation. Attention, learning, memory, and executive functioning were quantified in healthy adults. Right-handed carriers of the variant allele (G/A genotype, n = 29) performed worse on the d2 attention task than G/G homozygotes (n = 191). To test whether this difference reflects elevated homeostatic sleep pressure, sleep and sleep EEG before and after sleep deprivation were studied in 2 prospectively matched groups of G/A and G/G genotype subjects. Deep sleep and EEG 0.75- to 1.5-Hz oscillations in non-REM sleep were significantly higher in G/A than in G/G genotype. Moreover, attention and vigor were reduced, whereas waking EEG alpha activity (8.5-12 Hz), sleepiness, fatigue, and α-amylase in saliva were enhanced. These convergent data demonstrate that genetic reduction of ADA activity elevates sleep pressure and plays a key role in sleep and waking quality in humans.

  20. Court won't hear State claims as part of worker's ADA suit.

    Science.gov (United States)

    1997-09-19

    The 11th U.S. Circuit Court of Appeals cannot overturn a Federal judge's refusal to hear the State-law sexual harassment claims brought as part of an Americans with Disabilities Act (ADA) suit. [Name removed] filed Federal and State charges against Checkers drive-in restaurants. [Name removed] claims he was subjected to offensive and sexually exploitive language and was ridiculed as gay and having AIDS by one of his supervisors. According to [name removed], a separate supervisor pressured him to have sex and subjected him to physical contact. When [name removed] was fired, he filed an eight-count complaint under Federal and State law. He alleged that Checkers violated the Americans with Disabilities Act (ADA) because his supervisors believed he was HIV-positive and discriminated against him intentionally on that basis. He also sought recovery under the Florida AIDS discrimination statute and the Florida Civil Rights Act. The Federal judge decided not to handle the State-law claims and the 11th Circuit Court of Appeals refused to act on [name removed]'s appeal. Now [name removed] may have to choose either a Federal or a State court to hear all of his claims.

  1. ADA1 and NET1 genes of yeast mediate both chromosome maintenance and mitochondrial rho- mutagenesis

    International Nuclear Information System (INIS)

    Koltovaya, N.A.; Gerasimova, A.S.; Chekhuta, I.A.; Devin, A.B.

    2002-01-01

    An increase in the mitochondrial (mt) rho - mutagenesis is a well-known response of yeast cells to mutations in the numerous nuclear genes as well as to various kinds of stress. Notwithstanding the extensive studies during several decades the biological significance of this response is not yet fully understood. The genetic approach to solution of this subject includes the study of genes that are required for the high incidence of spontaneous rho - mutants. Previously we found that mutations in certain nuclear genes including CDC28, the central cell-cycle regulation gene, may decrease the spontaneous rho - mutability and simultaneously affect maintenance of the yeast chromosomes and plasmids. The present work provides data on identification of two more genes, resembling CDC28 in this respect. These genes NET1 and ADA1 mediate important regulatory protein-protein interactions in the yeast cell. The effects of net1 and ada1 mutations on the maintenance of yeast mt genome, chromosomes and plasmids as well on cell sensitivity to ionizing radiation are also described. (author)

  2. Subjetividades ameaçadas: mudança de nome de testemunhas protegidas

    Directory of Open Access Journals (Sweden)

    Cássia Maria Rosato

    2013-06-01

    Full Text Available Esse trabalho apresenta um estudo exploratório dos casos de mudança de identidade realizados no Brasil, no âmbito do Programa de Proteção a Vítimas e Testemunhas Ameaçadas, através da Lei Federal 9.807/99. Para tanto, parte dos conceitos de identidade e subjetividade como elementos-chave para identificar e compreender os impactos objetivos e subjetivos dessa medida de proteção. Como não existem estudos brasileiros empíricos sobre mudança de identidade, foram trazidas experiências de programas de proteção de outros países para compará-las à realidade brasileira. Para produzir esses dados foi feita a aplicação de questionários semiestruturados junto a profissionais ligados ao Programa. O objetivo dessa investigação buscou conhecer melhor a mudança de identidade como uma medida de proteção ainda pouco utilizada e consequentemente contribuir para o aperfeiçoamento da política brasileira. Por fim, reconhece-se a importância da Psicologia nos processos de mudança de nome de pessoas ameaçadas.

  3. Beyond the Law: A Review of Knowledge, Attitudes and Perceptions in ADA Employment Research

    Directory of Open Access Journals (Sweden)

    Robert Gould

    2015-09-01

    Full Text Available The Americans with Disabilities Act (ADA, 1990 is the cornerstone of civil rights policy for people with disabilities. Although enforced through the justice system, the legacy of the ADA transcends well beyond its legal ramifications. The policy’s framework and the rhetoric of Disability Rights suggest both an embrace of the spirit and the letter of the law, or promulgating both legislative and cultural change to ensure that the rights of people with disabilities are met.  In attempting to understand how and if such change has happened, researchers have gathered extensive evidence since 1990.  Much of this research evidence, however, remains fragmented, under-utilized, and at times inconclusive.  This article presents the results of a rapid evidence review of a sample of such research that is crucial to understand the ADA’s progress.  The study examines evidence about the ADA’s influence on knowledge, attitudes and perceptions about employment of people with disabilities. The research illustrates the importance of moving beyond the law to incorporate changes in knowledge about the law, perceptions of employability, and workplace culture.

  4. OFICINA DE ORIGAMI: ATIVIDADE DESENVOLVIDA NO ENSINO FUNDAMENTAL A PARTIR DO TEMA OLIMPÍADAS

    Directory of Open Access Journals (Sweden)

    Joyce dos Santos Vieira

    2017-05-01

    Full Text Available Utilizar diferentes metodologias e ferramentas em sala de aula exige do professor conhecimento e interesse por propiciarem um estímulo no processo de ensino-aprendizagem dos alunos. Neste trabalho foi desenvolvida uma oficina de origami para uma turma do 6º Ano do Ensino Fundamental da E.E.E.F.M. ”Professor Pedro Simão” no município de Alegre-ES. O objetivo da mesma foi confeccionar/representar alguns animais e plantas da fauna e flora brasileira para compor uma maquete para o projeto da escola com o tema das olimpíadas. A oficina foi realizada em três aulas com a confecção dos modelos de uma borboleta, um macaco e da flor vinca Catharanthus roseus, abordando a sustentabilidade e a preservação ambiental, ambos os temas relacionados às olimpíadas. A participação e o empenho dos alunos foram surpreendentes, evidenciando que atividades diferenciadas podem aproximar o aluno de qualquer tema que o professor queira abordar, quando trabalhado de forma contextualizada, propiciando uma interação entre alunos e professores.

  5. Evaluation of NASA GEOS-ADAS Modeled Diurnal Warming Through Comparisons to SEVIRI and AMSR2 SST Observations

    Science.gov (United States)

    Gentemann, C. L.; Akella, S.

    2018-02-01

    An analysis of the ocean skin Sea Surface Temperature (SST) has been included in the Goddard Earth Observing System (GEOS) - Atmospheric Data Assimilation System (ADAS), Version 5 (GEOS-ADAS). This analysis is based on the GEOS atmospheric general circulation model (AGCM) that simulates near-surface diurnal warming and cool skin effects. Analysis for the skin SST is performed along with the atmospheric state, including Advanced Very High Resolution Radiometer (AVHRR) satellite radiance observations as part of the data assimilation system. One month (September, 2015) of GEOS-ADAS SSTs were compared to collocated satellite Spinning Enhanced Visible and InfraRed Imager (SEVIRI) and Advanced Microwave Scanning Radiometer 2 (AMSR2) SSTs to examine how the GEOS-ADAS diurnal warming compares to the satellite measured warming. The spatial distribution of warming compares well to the satellite observed distributions. Specific diurnal events are analyzed to examine variability within a single day. The dependence of diurnal warming on wind speed, time of day, and daily average insolation is also examined. Overall the magnitude of GEOS-ADAS warming is similar to the warming inferred from satellite retrievals, but several weaknesses in the GEOS-AGCM simulated diurnal warming are identified and directly related back to specific features in the formulation of the diurnal warming model.

  6. Three sides of the same coin: measuring global cognitive impairment with the MMSE, ADAS-cog and CAMCOG.

    Science.gov (United States)

    Wouters, Hans; van Gool, Willem A; Schmand, Ben; Zwinderman, Aeilko H; Lindeboom, Robert

    2010-08-01

    The total scores of the ADAS-cog, MMSE and CAMCOG, comprising various cognitive tasks, are widely used to measure a dimension of global cognitive impairment. It is unknown, however, whether this dimension is common to these instruments. This hampers comparisons when either of these instruments is used. The extent to which these instruments share a common dimension of global cognitive impairment and how their scores relate was examined. Rasch analysis of CAMCOG and MMSE data of participants from a population based study and two memory clinics pooled with ADAS-cog and MMSE data of participants from three RCTs (overall N = 1566) to estimate a common dimension of global cognitive impairment and to examine the goodness of fit of the individual items to this dimension. Using the estimated common dimension of global cognitive impairment, the total scores of the instruments could be related, e.g. a mean level of global cognitive impairment corresponded to a predicted score of 11.4 (ADAS-cog), 72.6 (CAMCOG) and 22.2 (MMSE). When revised according to The Rasch validity analyses, every individual item could be fitted to the dimension. The MMSE, ADAS-cog and CAMCOG reflect a valid common dimension of global cognitive impairment, which enables comparisons of RCTs that use the ADAS-cog and observational studies that use the CAMCOG and MMSE.

  7. Longer-term effects of ADAS use on speed and headway control in drivers diagnosed with Parkinson's disease.

    Science.gov (United States)

    Dotzauer, Mandy; Caljouw, Simone R; De Waard, Dick; Brouwer, Wiebo H

    2015-01-01

    An advanced driver assistance system (ADAS) provided information about speed limits, speed, speeding, and following distance. Information was presented to the participants by means of a head-up display. Effects of the information on speed and headway control were studied in a longer-term driving simulator study including 12 repeated measures spread out over 4 weeks. Nine healthy older drivers between the ages of 65 and 82 years and 9 drivers between the ages of 68 and 82 years diagnosed with Parkinson's disease (PD) participated in the study. Within the 4 weeks, groups completed 12 consecutive sessions (10 with ADAS and 2 without ADAS) in a driving simulator. Results indicate an effect of ADAS use on performance. Removing ADAS after short-term exposure led to deterioration of performance in all speed measures in the group of drivers diagnosed with PD. These results suggest that provision of traffic information was utilized by drivers diagnosed with PD in order to control their speed.

  8. Role of ascitic fluid adenosine deaminase (ADA) and serum CA-125 in the diagnosis of tuberculous peritonitis.

    Science.gov (United States)

    Ali, N; Nath, N C; Parvin, R; Rahman, A; Bhuiyan, T M; Rahman, M; Mohsin M N

    2014-12-01

    This cross sectional study was carried out in the department of gastroenterology, BIRDEM, Dhaka from January 2010 to May 2011 to determine the role of ascitic fluid ADA and serum CA-125 in the diagnosis of clinically suspected tubercular peritonitis. Total 30 patients (age 39.69 ± 21.26, 18M/12F) with clinical suspicion of tuberculosis peritonitis were included in this study after analyzing selection criteria. Laparoscopic peritoneal biopsy with 'histopathological diagnosis' was considered gold standard against which accuracics of two biomarkers (ADA & CA-125) were compared. Cut off value of ADA and CA-125 are 24 u/l, 35 U/ml respectively. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of ADA as a diagnostic modality in tuberculos peritonitis were 87.5%, 83.33%, 95.45%, 62.5% and 86.67% respectively where as CA-125 was found to have 83.33% sensitivity, 50% specificity, 86.9% positive predictive value, 42.85% negative predictive value and 76.6% accuracy. Both biomarkers are simple, non-invasive, rapid and relatively cheap diagnostic test where as laparoscopy is an invasive procedure, costly & requires trained staff and not without risk and also not feasible in all the centre in our country. So ascitic fluid ADA and serum CA-125 are important diagnostic test for peritoneal tuberculosis.

  9. ADA (Trade Name) Software Engineering Education and Training Symposium (2nd) Held in Dallas, Texas on 9-11 June 1987.

    Science.gov (United States)

    1987-06-11

    started implementing the programming language Ada as the departamental language. After almost 3 years into the project, we feel we have succeeded. The...of the following topics University Setting. Departamental Setting Curriculum overview. Ada as a Primary Programming Language. Ada curriculum... departamental language I proceed to state our common teaching philosophy and goals. at least with respect to the programming courses. In our teaching

  10. Clinical significance of combined determination of the changes of the serum ADA, HA and PIIIP levels in patients with hepatitis B

    International Nuclear Information System (INIS)

    Wang Xiaoyan

    2009-01-01

    Objective: To explore the clinical significance of the changes of serum ADA, HA and PIIIP levels in patients with hepatitis B. Methods: Serum adenosine deaminase (ADA) (with biochemistry) and HA PIIIP (with RIA) levels were determined in 102 patients with hepatitis B of various stages and 35 controls. Results: Serum ADA, HA and PIIIP levels in patients with hepatitis B were significantly higher than those in controls (P<0.01). Particularly in patients with cirrhosis (n=13) (P<0.001). Conclusion: The serum ADA, HA and PIIIP levels were closely related to the diseases process of hepatitis B and were of great clinical values. (authors)

  11. Derivation of a new ADAS-cog composite using tree-based multivariate analysis: prediction of conversion from mild cognitive impairment to Alzheimer disease.

    Science.gov (United States)

    Llano, Daniel A; Laforet, Genevieve; Devanarayan, Viswanath

    2011-01-01

    Model-based statistical approaches were used to compare the ability of the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog), cerebrospinal fluid (CSF), fluorodeoxyglucose positron emission tomography and volumetric magnetic resonance imaging (MRI) markers to predict 12-month progression from mild cognitive impairment (MCI) to Alzheimer disease (AD). Using the Alzheimer's Disease Neuroimaging Initiative (ADNI) data set, properties of the 11-item ADAS-cog (ADAS.11), the 13-item ADAS-cog (ADAS.All) and novel composite scores were compared, using weighting schemes derived from the Random Forests (RF) tree-based multivariate model. Weighting subscores using the RF model of ADAS.All enhanced discrimination between elderly controls, MCI and AD patients. The ability of the RF-weighted ADAS-cog composite and individual scores, along with neuroimaging or biochemical biomarkers to predict MCI to AD conversion over 12 months was also assessed. Although originally optimized to discriminate across diagnostic categories, the ADAS. All, weighted according to the RF model, did nearly as well or better than individual or composite baseline neuroimaging or CSF biomarkers in prediction of 12-month conversion from MCI to AD. These suggest that a modified subscore weighting scheme applied to the 13-item ADAS-cog is comparable to imaging or CSF markers in prediction of conversion from MCI to AD at 12 months. Copyright © 2011 by Lippincott Williams & Wilkins

  12. Using Penelope to assess the correctness of NASA Ada software: A demonstration of formal methods as a counterpart to testing

    Science.gov (United States)

    Eichenlaub, Carl T.; Harper, C. Douglas; Hird, Geoffrey

    1993-01-01

    Life-critical applications warrant a higher level of software reliability than has yet been achieved. Since it is not certain that traditional methods alone can provide the required ultra reliability, new methods should be examined as supplements or replacements. This paper describes a mathematical counterpart to the traditional process of empirical testing. ORA's Penelope verification system is demonstrated as a tool for evaluating the correctness of Ada software. Grady Booch's Ada calendar utility package, obtained through NASA, was specified in the Larch/Ada language. Formal verification in the Penelope environment established that many of the package's subprograms met their specifications. In other subprograms, failed attempts at verification revealed several errors that had escaped detection by testing.

  13. Structural controls on diffuse degassing in the Las Cañadas caldera, Tenerife, Canary Islands

    Science.gov (United States)

    Galindo, I.; Soriano, C.; Martí, J.; Pérez, N.

    2003-04-01

    The Las Cañadas caldera is an elliptical depression located in the central part of the Tenerife Island. The active Teide stratovolcano stands in the centre of the depression, which is limited to the south by the caldera wall, up to 500 m high above the caldera floor. Mapping most of the caldera wall at 1:5000 has provided new insights on its stratigraphy, structure, and geological evolution. Three major ENE-WSW normal faults have been mapped on the caldera wall in the area comprised between El Llano de Ucanca and Los Azulejos, where an intense hydrothermal alteration affects the lower stratigraphic levels of the caldera wall. Hydrothermal alteration is rather distinctive in this area, showing bluish to greenish colours. Most of the phonolitic cone sheets and radial dykes of the caldera wall do not show distinctive hydrothermal features, as do show the phonolitic pyroclastic rocks and lavas of the lower parts of the caldera wall. This suggests the main episodes of dyke intrusion in the Las Cañadas caldera postdate hydrothermal alteration. ENE-WSW normal faults involve dyke swarms and rocks of the upper stratigraphic levels of the caldera wall, and show displacements of up to 100 m. Unfortunately the upper possible age of these faults is poorly constrained since no contact relationship has been observed between fault planes and the rocks of the uppermost stratigraphic levels of the caldera wall. The rocks of the caldera wall adjacent to the faults are intensely fractured at the macro and mesoscale. In addition to field mapping, a soil gas survey was carried out at the caldera depression. Soil CO2 efflux and H2 concentration were measured reaching values of 12 gm-2d-1 and 4 ppmV, respectively. Spatial distribution of these species showed that positive anomalies coincide with the surface expression of the three major faults and their adjacent intensely fractured zone. The high CO2 and H2 values and their coincidence with major normal faults suggests that degassing in

  14. SMARTPHONE-BASED APPROACH TO ADVANCED DRIVER ASSISTANCE SYSTEM (ADAS RESEARCH AND DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    I. B. Lashkov

    2015-11-01

    Full Text Available Subject of Research.The paper deals with findings and presents asmartphone-based approach to advanced driver assistance system (ADAS research and development.The approach is based on the data of smartphone cameras and sensors. The line of researchis associated with the developmentof mobile advanced driver assistance system (ADAS. Method.The proposedapproach isbased on the use of driver'sand vehicle behavior ontologies. Current ADAS systems can be divided into two main categories according to the method of implementation: mobile applications, manually installed by the driver from the application stores, and safetyhardware and softwaresystems,integrated into vehicles by manufacturesor in the automotive service centers.Mobile application installed on the smartphone uses the built-in rear and front-facing cameras and sensors to monitor both the road and vehicles ahead, and at the same time the driver in order to prevent traffic collisions. The service consists of components for objects recognition in the images obtained with cameras, and components for traffic situation analysis. Main Results. The driver safety mobile application has been developedfor the use on mobile phones.The mobile phone is mounted on the windshield of a car.In case of dangerous event occurrence, the application engine will make an audible or vibration signal to inform the driver to be concentratedand more vigilant. For example, road obstacles, rear-end and stationary vehicle accidents are the most common accident types.The mobile application detects whether a crash is imminent by computing the ‘Time To Contact’ (TTC taking into account host vehicle speed, relative speed and relative acceleration.If the driver doesn’t maintain safe minimum distance with the car immediately ahead, the mobile application will alert the driver by displaying an attention icon with an audible alert. The dual-camera sensing application is designed to help the drivers increase the trip safety

  15. Psicópatas integrados en las relaciones de pareja: la tríada oscura de la personalidad

    OpenAIRE

    Pozueco Romero, José Manuel

    2016-01-01

    Tres son los principales perfiles de personalidad que se ha constatado influyen muy negativamente en cualquier tipo de relación íntima, ya sea ésta de corta o larga duración: la psicopatía, el maquiavelismo y el narcisismo. Al grupo de estos tres tipos de personalidades se les conoce como la tríada oscura de la personalidad. Diversos estudios han investigado las relaciones entre esta tríada oscura de la personalidad y las relaciones amorosas, evidenciando que emplean diversas tácticas de c...

  16. The neuro-glial properties of adipose-derived adult stromal (ADAS) cells are not regulated by Notch 1 and are not derived from neural crest lineage.

    Science.gov (United States)

    Wrage, Philip C; Tran, Thi; To, Khai; Keefer, Edward W; Ruhn, Kelly A; Hong, John; Hattangadi, Supriya; Treviño, Isaac; Tansey, Malú G

    2008-01-16

    We investigated whether adipose-derived adult stromal (ADAS) are of neural crest origin and the extent to which Notch 1 regulates their growth and differentiation. Mouse ADAS cells cultured in media formulated for neural stem cells (NSC) displayed limited capacity for self-renewal, clonogenicity, and neurosphere formation compared to NSC from the subventricular zone in the hippocampus. Although ADAS cells expressed Nestin, GFAP, NSE and Tuj1 in vitro, exposure to NSC differentiation supplements did not induce mature neuronal marker expression. In contrast, in mesenchymal stem cell (MSC) media, ADAS cells retained their ability to proliferate and differentiate beyond 20 passages and expressed high levels of Nestin. In neuritizing cocktails, ADAS cells extended processes, downregulated Nestin expression, and displayed depolarization-induced Ca(2+) transients but no spontaneous or evoked neural network activity on Multi-Electrode Arrays. Deletion of Notch 1 in ADAS cell cultures grown in NSC proliferation medium did not significantly alter their proliferative potential in vitro or the differentiation-induced downregulation of Nestin. Co-culture of ADAS cells with fibroblasts that stably expressed the Notch ligand Jagged 1 or overexpression of the Notch intracellular domain (NICD) did not alter ADAS cell growth, morphology, or cellular marker expression. ADAS cells did not display robust expression of neural crest transcription factors or genes (Sox, CRABP2, and TH); and lineage tracing analyses using Wnt1-Cre;Rosa26R-lacZ or -EYFP reporter mice confirmed that fewer than 2% of the ADAS cell population derived from a Wnt1-positive population during development. In summary, although media formulations optimized for MSCs or NSCs enable expansion of mouse ADAS cells in vitro, we find no evidence that these cells are of neural crest origin, that they can undergo robust terminal differentiation into functionally mature neurons, and that Notch 1 is likely to be a key

  17. Rdesign: A data dictionary with relational database design capabilities in Ada

    Science.gov (United States)

    Lekkos, Anthony A.; Kwok, Teresa Ting-Yin

    1986-01-01

    Data Dictionary is defined to be the set of all data attributes, which describe data objects in terms of their intrinsic attributes, such as name, type, size, format and definition. It is recognized as the data base for the Information Resource Management, to facilitate understanding and communication about the relationship between systems applications and systems data usage and to help assist in achieving data independence by permitting systems applications to access data knowledge of the location or storage characteristics of the data in the system. A research and development effort to use Ada has produced a data dictionary with data base design capabilities. This project supports data specification and analysis and offers a choice of the relational, network, and hierarchical model for logical data based design. It provides a highly integrated set of analysis and design transformation tools which range from templates for data element definition, spreadsheet for defining functional dependencies, normalization, to logical design generator.

  18. Multiclass AdaBoost ELM and Its Application in LBP Based Face Recognition

    Directory of Open Access Journals (Sweden)

    Yunliang Jiang

    2015-01-01

    Full Text Available Extreme learning machine (ELM is a competitive machine learning technique, which is simple in theory and fast in implementation; it can identify faults quickly and precisely as compared with traditional identification techniques such as support vector machines (SVM. As verified by the simulation results, ELM tends to have better scalability and can achieve much better generalization performance and much faster learning speed compared with traditional SVM. In this paper, we introduce a multiclass AdaBoost based ELM ensemble method. In our approach, the ELM algorithm is selected as the basic ensemble predictor due to its rapid speed and good performance. Compared with the existing boosting ELM algorithm, our algorithm can be directly used in multiclass classification problem. We also carried out comparable experiments with face recognition datasets. The experimental results show that the proposed algorithm can not only make the predicting result more stable, but also achieve better generalization performance.

  19. Lessons learned applying CASE methods/tools to Ada software development projects

    Science.gov (United States)

    Blumberg, Maurice H.; Randall, Richard L.

    1993-01-01

    This paper describes the lessons learned from introducing CASE methods/tools into organizations and applying them to actual Ada software development projects. This paper will be useful to any organization planning to introduce a software engineering environment (SEE) or evolving an existing one. It contains management level lessons learned, as well as lessons learned in using specific SEE tools/methods. The experiences presented are from Alpha Test projects established under the STARS (Software Technology for Adaptable and Reliable Systems) project. They reflect the front end efforts by those projects to understand the tools/methods, initial experiences in their introduction and use, and later experiences in the use of specific tools/methods and the introduction of new ones.

  20. Analysis of angular dependent Auger spectroscopy (ADAS) based on a quasiatomic model

    International Nuclear Information System (INIS)

    Davis, H.L.

    1977-01-01

    Calculated results are presented which are in good agreement with published M 2 , 3 VV Cu (100) ADAS data. The calculations are based on a quasiatomic model where each individual Auger emission is a partial wave of definite (l,m) character, but (l,m) may differ from emission to emission. The (l,m) emission weights have been estimated by fitting the data with a linear combination of calculated intensities for (l,m) up to l = 5. It is found that surprisingly few (l,m) values are necessary to obtain reasonable fits to the data, and the best fits occur for combinations of (l,m) intensities in which the l = 3 waves were most heavily weighted

  1. Design Method of ADAS for Urban Electric Vehicle Based on Virtual Prototyping

    Directory of Open Access Journals (Sweden)

    Katarzyna Jezierska-Krupa

    2018-01-01

    Full Text Available Since 2012, the Smart Power Team has been actively participating in the Shell Eco-marathon, which is a worldwide competition. From the very beginning, the team has been working to increase driver’s safety on the road by developing Advanced Driver Assistance Systems. This paper presents unique method for designing ADAS systems in order to minimize the costs of the design phase and system implementation and, at the same time, to maximize the positive effect the system has on driver and vehicle safety. The described method is based on using virtual prototyping tool to simulate the system performance in real-life situations. This approach enabled an iterative design process, which resulted in reduction of errors with almost no prototyping and testing costs.

  2. POLIMEROS COMO METODOS PARA RECUPERAÇÃO AVANÇADA DE PETRÓLEO

    OpenAIRE

    Marques, Landson S.; UFBA; Quintella, Cristina M.; UFBA; Neto, Guilherme João Musse; UFBA; Cavalcanti, David Falcão; UFBA; Santos, Lauro Tiago Souza; UFBA

    2014-01-01

    A recuperação terciária ou avançada de petróleo (EOR) com a injeção de soluções diluídas de um polímero nos reservatórios ajuda a deslocar o óleo dos poros atuando na viscosidade do fluido injetado e na molhabilidade. EOR é utilizada especialmente quando aumenta a demanda por petróleo e seus derivados. EOR com polímeros tem sido patenteada desde 1967 e continua até aos dias de hoje em pequenas ondas. Os EUA têm o maior número de patentes. A grandes depositantes são as maiores empresas de p...

  3. The Comparison Flow of Four Impression Compounds (Green Stick with ADA Standard

    Directory of Open Access Journals (Sweden)

    S. Mir Mohammad Rezaei

    2004-09-01

    Full Text Available Statement of Problem: Low- fusing compound (type 1 is used for border molding and impressions. Flow and reproducibility of surface detail are two important characteristics of these materials. There are no valid data available comparing domestic and imported brands.Purpose: The Purpose of this study was to evaluate these two properties of four different products including Kerr (Kerr Manufacture MI 98174-2600, Harvard (Hoffman Harvard Dental GMb H Germany; Kymia (Kymia dental company 713 Iran; and Pishro (Pishro72534 Iran.Materials and Methods: All procedures were followed according to ADA and BSStandard.Total number of 48 samples were divided into 8 groups (6 in each group.Twenty disks were fabricated for impression tests. The specimen dimensions were 40 mm (diameter and 6mm (thickness. Standard test blocks were used to test the specimens.Results: The Willcoxon test showed significant difference in flow rate between materials tested with the best result for Kerr (P<0.05. Kerr flow was 85% and under 5% at 45°C and 37°C, respectively. There were great deviations from standards value at 45°C. For the rest of the samples at 37°C; except Kymia the flow rate for 3 materials (Kerr; Harvard Pishrowere almost acceptable. The impression test results revealed that only Kerr was able torecord the details at 45°C.Conclusion: Kerr flow is exactly what ADA standards specify. But the flow rate for three materials exhibit a great distance from these standards. In impression test only Kerr was able to record the details

  4. Distribution of Isotopic and Environmental Tracers in Groundwater, Northern Ada County, Southwestern Idaho

    Science.gov (United States)

    Adkins, Candice B.; Bartolino, James R.

    2010-01-01

    Residents of northern Ada County, Idaho, depend on groundwater for domestic and agricultural uses. The population of this area is growing rapidly and groundwater resources must be understood for future water-resource management. The U.S. Geological Survey, in cooperation with the Idaho Department of Water Resources, used a suite of isotopic and environmental tracers to gain a better understanding of groundwater ages, recharge sources, and flowpaths in northern Ada County. Thirteen wells were sampled between September and October 2009 for field parameters, major anions and cations, nutrients, oxygen and hydrogen isotopes, tritium, radiocarbon, chlorofluorocarbons, and dissolved gasses. Well depths ranged from 30 to 580 feet below land surface. Wells were grouped together based on their depth and geographic location into the following four categories: shallow aquifer, intermediate/deep aquifer, Willow Creek aquifer, and Dry Creek aquifer. Major cations and anions indicated calcium-bicarbonate and sodium-bicarbonate water types in the study area. Oxygen and hydrogen isotopes carried an oxygen-18 excess signature, possibly indicating recharge from evaporated sources or water-rock interactions in the subsurface. Chlorofluorocarbons detected modern (post-1940s) recharge in every well sampled; tritium data indicated modern water (post-1951) in seven, predominantly shallow wells. Nutrient concentrations tended to be greater in wells signaling recent recharge based on groundwater age dating, thus confirming the presence of recent recharge in these wells. Corrected radiocarbon results generated estimated residence times from modern to 5,100 years before present. Residence time tended to increase with depth, as confirmed by all three age-tracers. The disagreement among residence times indicates that samples were well-mixed and that the sampled aquifers contain a mixture of young and old recharge. Due to a lack of data, no conclusions about sources of recharge could be drawn

  5. New scoring methodology improves the sensitivity of the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog) in clinical trials.

    Science.gov (United States)

    Verma, Nishant; Beretvas, S Natasha; Pascual, Belen; Masdeu, Joseph C; Markey, Mia K

    2015-11-12

    As currently used, the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog) has low sensitivity for measuring Alzheimer's disease progression in clinical trials. A major reason behind the low sensitivity is its sub-optimal scoring methodology, which can be improved to obtain better sensitivity. Using item response theory, we developed a new scoring methodology (ADAS-CogIRT) for the ADAS-Cog, which addresses several major limitations of the current scoring methodology. The sensitivity of the ADAS-CogIRT methodology was evaluated using clinical trial simulations as well as a negative clinical trial, which had shown an evidence of a treatment effect. The ADAS-Cog was found to measure impairment in three cognitive domains of memory, language, and praxis. The ADAS-CogIRT methodology required significantly fewer patients and shorter trial durations as compared to the current scoring methodology when both were evaluated in simulated clinical trials. When validated on data from a real clinical trial, the ADAS-CogIRT methodology had higher sensitivity than the current scoring methodology in detecting the treatment effect. The proposed scoring methodology significantly improves the sensitivity of the ADAS-Cog in measuring progression of cognitive impairment in clinical trials focused in the mild-to-moderate Alzheimer's disease stage. This provides a boost to the efficiency of clinical trials requiring fewer patients and shorter durations for investigating disease-modifying treatments.

  6. La tríada oscura de la personalidad: maquiavelismo, narcisismo y psicopatía. Una mirada evolutiva

    Directory of Open Access Journals (Sweden)

    Fernando Renee González Moraga

    2015-08-01

    Full Text Available Se aborda la denominada Tríada Oscura de la Personalidad -Tríada- (maquiavelismo, narcisismo subclínico y psicopatía subclínica desde una mirada evolutiva. El objetivo de esta investigación es revisar la evidencia que han presentado los teóricos evolucionistas sobre la Tríada, desde un acercamiento a la mirada evolutiva. Para esto, se indaga en las principales características de cada uno de estos rasgos, los instrumentos que se han utilizado para evaluarlos y las principales áreas en donde se han estudiado. La mirada evolutiva plantea que los rasgos de la Tríada son dimensionales y varían de acuerdo con las diversas estrategias que utilizan los sujetos para adaptarse a las características socioambientales en las que se desarrollan. Estos rasgos se caracterizan por presentar violencia psicológica, inhibición moral, manipulación, baja amabilidad, insensibilidad, egoísmo y dificultad para mentalizar en contextos de interacción interpersonal y social.

  7. Rezension: Ada Lovelace. Die Pionierin der Computertechnik und ihre Nachfolgerinnen von Sybille Krämer (Hg.

    Directory of Open Access Journals (Sweden)

    Bettina Schabschneider

    2015-12-01

    Full Text Available Ein aktueller von Sybille Krämer herausgegebener Sammelband beleuchtet die Bedeutung der Computertechnik-Pionierin Ada Lovelace. Bettina Schabschneider hat den Band einer detaillierten Lektüre unterzogen und für die MEDIENIMPULSE rezensiert …

  8. Software Technology for Adaptable, Reliable Systems (STARS). Repository Integration AdaKNET Software User’s Manual

    Science.gov (United States)

    1990-10-03

    knowledge bases via amalgama - tion of small, special-ptupose knowledge bases. For example, a fragment of the Gadfly knowledge base describing Ada...amalgamations must have as their root concept a generic con- cept which exists in the current network specification. The interpretation of amalgama - tons is

  9. Identifying Faculty Perceptions of Awareness and Preparedness Relating to ADA Compliance at a Small, Private College in NE PA

    Science.gov (United States)

    Stevens, Chad M.; Schneider, Elizabeth; Bederman-Miller, Patricia

    2018-01-01

    This paper explores post-secondary faculty perceptions of awareness and preparedness relating to Americans with Disabilities Act (ADA). Institutions of higher education are businesses. The largest threat to sustained viability for many businesses is litigation. Business-related litigation is often the result of non-employment discrimination or…

  10. Reviews: Effects of transdermal rivastigmine on ADAS-cog items in mild-to-moderate Alzheimer's disease.

    Science.gov (United States)

    Grossberg, George T; Schmitt, Frederick A; Meng, Xiangyi; Tekin, Sibel; Olin, Jason

    2010-12-01

    Alzheimer's disease (AD) patients treated with rivastigmine transdermal patch have shown statistically significant differences versus placebo on the AD Assessment scale-cognitive subscale (ADAS-cog). In this retrospective analysis of a double-blind, placebo- and active-controlled, 24-week clinical trial, the specific effects of rivastigmine patch on individual ADAS-cog items and cognitive domains (memory, language, and praxis) were explored. The mean baseline to week 24 changes were calculated for each ADAS-cog item and domain in this exploratory, hypothesis-generating analysis. Patients on 9.5 mg/24 h rivastigmine patch, 17.4 mg/24 h rivastigmine patch, and 3 to 12 mg/d rivastigmine capsules showed improvements over placebo on the memory and praxis ADAS-cog subscales. The rivastigmine patch groups also showed improvements on the language subscale. Significant differences versus placebo were seen on several individual item scores in the rivastigmine-treated groups. Rivastigmine patch was associated with improvements on the memory, praxis, and language domains of cognition in patients with mild-to-moderate AD.

  11. The stability of AQT processing speed, ADAS-Cog and MMSE during acetylcholinesterase inhibitor treatment in Alzheimer's disease.

    Science.gov (United States)

    Wiig, E H; Annas, P; Basun, H; Andreasen, N; Lannfelt, L; Zetterberg, H; Blennow, K; Minthon, L

    2010-03-01

    To explore the longitudinal stability of measures of cognition during treatment with acetylcholinesterase inhibitors (AchEI) in patients with Alzheimer's disease (AD). Cognitive status was measured in a cohort of 60 patients at 6 months after initiation of treatment with AchEI (baseline) and after an additional 6 months of treatment (endpoint). A Quick Test of Cognitive Speed (AQT), Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog), and MMSE were administered concurrently. Correlations (rho) between age and AQT processing speed were non-significant, but were significant for ADAS-Cog and Mini Mental State Examination (MMSE). AQT and ADAS-Cog means did not differ significantly between baseline and endpoint. There was a small, significant reduction in MMSE point scores. Measures of stability (Spearman's rho) were moderate-to-high for all tests. Means for subgroups did not differ as a function of medication type. AQT processing speed, ADAS-Cog, and MMSE measures proved stable during the second 6 months of treatment with AChEI.

  12. Reliability prediction for the vehicles equipped with advanced driver assistance systems (ADAS and passive safety systems (PSS

    Directory of Open Access Journals (Sweden)

    Balbir S. Dhillon

    2012-10-01

    Full Text Available The human error has been reported as a major root cause in road accidents in today’s world. The human as a driver in road vehicles composed of human, mechanical and electrical components is constantly exposed to changing surroundings (e.g., road conditions, environmentwhich deteriorate the driver’s capacities leading to a potential accident. The auto industries and transportation authorities have realized that similar to other complex and safety sensitive transportation systems, the road vehicles need to rely on both advanced technologies (i.e., Advanced Driver Assistance Systems (ADAS and Passive Safety Systems (PSS (e.g.,, seatbelts, airbags in order to mitigate the risk of accidents and casualties. In this study, the advantages and disadvantages of ADAS as active safety systems as well as passive safety systems in road vehicles have been discussed. Also, this study proposes models that analyze the interactions between human as a driver and ADAS Warning and Crash Avoidance Systems and PSS in the design of vehicles. Thereafter, the mathematical models have been developed to make reliability prediction at any given time on the road transportation for vehicles equipped with ADAS and PSS. Finally, the implications of this study in the improvement of vehicle designs and prevention of casualties are discussed.

  13. Longer-term effects of ADAS use on speed and headway control in drivers diagnosed with Parkinson's disease

    NARCIS (Netherlands)

    Dotzauer, Mandy; Caljouw, Simone R.; De Waard, Dick; Brouwer, Wiebo H.

    2015-01-01

    Objective: An advanced driver assistance system (ADAS) provided information about speed limits, speed, speeding, and following distance. Information was presented to the participants by means of a head-up display. Methods: Effects of the information on speed and headway control were studied in a

  14. The ADAS-cog in Alzheimer's disease clinical trials: psychometric evaluation of the sum and its parts.

    Science.gov (United States)

    Cano, Stefan J; Posner, Holly B; Moline, Margaret L; Hurt, Stephen W; Swartz, Jina; Hsu, Tim; Hobart, Jeremy C

    2010-12-01

    The Alzheimer's Disease Assessment Scale Cognitive Behavior Section (ADAS-cog), a measure of cognitive performance, has been used widely in Alzheimer's disease trials. Its key role in clinical trials should be supported by evidence that it is both clinically meaningful and scientifically sound. Its conceptual and neuropsychological underpinnings are well-considered, but its performance as an instrument of measurement has received less attention. Objective To examine the traditional psychometric properties of the ADAS-cog in a large sample of people with Alzheimer's disease. Data from three clinical trials of donepezil (Aricept) in mild-to-moderate Alzheimer's disease (n=1421; MMSE 10-26) were analysed at both the scale and component level. Five psychometric properties were examined using traditional psychometric methods. These methods of examination underpin upcoming Food and Drug Administration recommendations for patient rating scale evaluation. At the scale-level, criteria tested for data completeness, scaling assumptions (eg, component total correlations: 0.39-0.67), targeting (no floor or ceiling effects), reliability (eg, Cronbach's α: = 0.84; test-retest intraclass correlations: 0.93) and validity (correlation with MMSE: -0.63) were satisfied. At the component level, 7 of 11 ADAS-cog components had substantial ceiling effects (range 40-64%). Performance was satisfactory at the scale level, but most ADAS-cog components were too easy for many patients in this sample and did not reflect the expected depth and range of cognitive performance. The clinical implication of this finding is that the ADAS-cog's estimate of cognitive ability, and its potential ability to detect differences in cognitive performance under treatment, could be improved. However, because of the limitations of traditional psychometric methods, further evaluations would be desirable using additional rating scale analysis techniques to pinpoint specific improvements.

  15. Volcanic geomorphosites and geotourism in Las Cañadas del Teide National Park, Tenerife, Canary Islands, Spain

    Science.gov (United States)

    Dóniz-Paéz, Javier; Becerra-Ramírez, Rafael; González-Cárdenas, Elena; Rodriguez, Fátima

    2017-04-01

    Geomorphosites and geoturism studies are increasing for the high scientific, societal, cultural, and aesthetic values of the relief. Volcanic areas are exciting targets for such studies for their geodiversity. The aim of these study is an inventory of volcanic geomorphosites and its relationship to geotourism. Las Cañadas del Teide National Park (LCTNP) is a volcanic complex area located in the central part of Tenerife island (Canary Islands, Spain). This area is a volcanic paradise rich in spectacular landforms: stratovolcanoes, calderas, cinder cones, craters, pahoehoe, aa, block and balls lavas, gullies, etc. The national park is registered in the world heritage list (UNESCO) in 2007 as a natural site. The LCTNP receives more than 2,5 million tourists per year and it has 21 main pahts and 14 secondary ones. For the selection of the geomophosites the LCTNP was divided into four geomorphological units (Teide-Pico Viejo stratovolcanoes, Las Cañadas Caldera wall, the bottom of Las Cañadas and the basaltic volcanic field) and each one of them is selected the most representative geomorphosites by its geodiversity, because of its geomorphological heritage, its landscapes and its tourist potential with the paths. All selected geomorphosites are within areas where public use is allowed in the park. The inventory classifies the 23 geomorphosites in two main categories: (a) direct volcanic with 17 geomorphosites (stratovolcanoes, domes, cinder cones, pahoehoe, aa and bloc lava flows, etc.) and (b) eroded volcanic landforms with 6 (wall of Las Cañadas caldera, talusees, foodplains, etc.). The Teide-Pico Viejo unit is which has more geomorphosites with 8 and the Las Cañadas wall unit possessing less with 5. The assessment evaluates the scientific, cultural/historical, and use values and helps to define priorities in site management. These geomorphosites demonstrate the volcanic history and processes of the LCTNP.

  16. The Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog): Modifications and Responsiveness in Pre-Dementia Populations. A Narrative Review.

    Science.gov (United States)

    Kueper, Jacqueline K; Speechley, Mark; Montero-Odasso, Manuel

    2018-01-01

    The Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) was developed in the 1980s to assess the level of cognitive dysfunction in Alzheimer's disease. Advancements in the research field have shifted focus toward pre-dementia populations, and use of the ADAS-Cog has extended into these pre-dementia studies despite concerns about its ability to detect important changes at these milder stages of disease progression. If the ADAS-Cog cannot detect important changes, our understanding of pre-dementia disease progression may be compromised and trials may incorrectly conclude that a novel treatment approach is not beneficial. The purpose of this review was to assess the performance of the ADAS-Cog in pre-dementia populations, and to review all modifications that have been made to the ADAS-Cog to improve its measurement performance in dementia or pre-dementia populations. The contents of this review are based on bibliographic searches of electronic databases to locate all studies using the ADAS-Cog in pre-dementia samples or subsamples, and to locate all modified versions. Citations from relevant articles were also consulted. Overall, our results suggest the original ADAS-Cog is not an optimal outcome measure for pre-dementia studies; however, given the prominence of the ADAS-Cog, care must be taken when considering the use of alternative outcome measures. Thirty-one modified versions of the ADAS-Cog were found. Modification approaches that appear most beneficial include altering scoring methodology or adding tests of memory, executive function, and/or daily functioning. Although modifications improve the performance of the ADAS-Cog, this is at the cost of introducing heterogeneity that may limit between-study comparison.

  17. An Arabic Version of the Cognitive Subscale of the Alzheimer's Disease Assessment Scale (ADAS-Cog): Reliability, Validity, and Normative Data.

    Science.gov (United States)

    Ben Jemaa, Sonia; Attia Romdhane, Neila; Bahri-Mrabet, Amel; Jendli, Adel; Le Gall, Didier; Bellaj, Tarek

    2017-01-01

    The Alzheimer's Disease Assessment Scale's cognitive subscale (ADAS-Cog) is the most widely used instrument for screening cognitive dysfunction in Alzheimer's disease. The aim of the present study was to develop an Arabic version of this scale (A-ADAS-Cog), examine its psychometric properties (reliability and validity), and provide normative data. The A-ADAS-Cog), an Arabic version of the Mini-Mental State Examination (A-MMSE), and a Standardized Clinical Dementia Rating Scale (CDR) were administered to three Tunisian groups: 124 normal controls (NC), 33 patients with non-Alzheimer dementia (N-AD), and 25 patients with Alzheimer's disease (AD). The A-ADAS-Cog scores were significantly affected by age and education. A correction table was constructed to control these effects. The results showed that the A-ADAS-Cog has good internal consistency and reliability (α= 0.82 for AD). The test-retest reliability of the A-ADAS-Cog was stable over time (r = 0.97). An evaluation of the construct validity of the A-ADAS-Cog using principal component analysis led to a solution with three factors (memory, language and praxis), which explained 72% of the variance. The concurrent validity of the A-ADAS-Cog was established using the A-MMSE score (r = -0.86), CDR Sum of Boxes score (CDR-SB; r = 0.87), and global CDR score (CDR-Global; r = 0.74). Finally, the A-ADAS-Cog has an excellent discriminating power in the diagnosis of AD (ROC area = 0.92). A cut-off score of 10 (sensitivity = 84% and specificity = 91%) is indicated for the screening of the AD. Overall, the results indicated that the A-ADAS-Cog is psychometrically reliable and valid and provides promising results for screening of dementia in Arabic speaking patients.

  18. The Alzheimer’s Disease Assessment Scale–Cognitive Subscale (ADAS-Cog): Modifications and Responsiveness in Pre-Dementia Populations. A Narrative Review

    Science.gov (United States)

    Kueper, Jacqueline K.; Speechley, Mark; Montero-Odasso, Manuel

    2018-01-01

    The Alzheimer’s Disease Assessment Scale–Cognitive Subscale (ADAS-Cog) was developed in the 1980s to assess the level of cognitive dysfunction in Alzheimer’s disease. Advancements in the research field have shifted focus toward pre-dementia populations, and use of the ADAS-Cog has extended into these pre-dementia studies despite concerns about its ability to detect important changes at these milder stages of disease progression. If the ADAS-Cog cannot detect important changes, our understanding of pre-dementia disease progression may be compromised and trials may incorrectly conclude that a novel treatment approach is not beneficial. The purpose of this review was to assess the performance of the ADAS-Cog in pre-dementia populations, and to review all modifications that have been made to the ADAS-Cog to improve its measurement performance in dementia or pre-dementia populations. The contents of this review are based on bibliographic searches of electronic databases to locate all studies using the ADAS-Cog in pre-dementia samples or subsamples, and to locate all modified versions. Citations from relevant articles were also consulted. Overall, our results suggest the original ADAS-Cog is not an optimal outcome measure for pre-dementia studies; however, given the prominence of the ADAS-Cog, care must be taken when considering the use of alternative outcome measures. Thirty-one modified versions of the ADAS-Cog were found. Modification approaches that appear most beneficial include altering scoring methodology or adding tests of memory, executive function, and/or daily functioning. Although modifications improve the performance of the ADAS-Cog, this is at the cost of introducing heterogeneity that may limit between-study comparison. PMID:29660938

  19. PS1-35: Impact of an ADA-Accredited Diabetes Education on Healthcare Utilization

    Science.gov (United States)

    Basu, Rashmita; Allenson, Sarah; McLellan, Lynn; Hochhalter, Angela

    2012-01-01

    Background/Aims Diabetes self-management education delivered by certified diabetes educators (CDE) can improve persons’ self-management skills, self-efficacy for managing their diabetes, and clinical outcomes among patients with Type II diabetes. In addition, these education programs have the potential to reduce healthcare utilization, costs, and disabilities associated with the disease. Objective The purpose of this study was to measure the impact of Type 2 Diabetes BASICS education program (obtained from the International Diabetes Center in Minneapolis) on healthcare utilization among Scott & White SeniorCare members. The Diabetes Education site at Scott & White is nationally certified by the American Diabetes Association (ADA). Methods This was a retrospective cohort study of participants who attended the education program at a single program delivery site. Subjects were program participants who attended four BASICS class sessions over a six months period between January 2005 and July 2010 and were also enrolled in a Medicare Cost Contract product. About 349 subjects were included in the analysis. The key outcome variables were number of outpatient visits, number of inpatient hospitalization and length of inpatient stay. Differences in average number of outpatient visits, number of inpatient hospitalization, and length of inpatient stay were compared for the 12-months before participants began the education program and the 12-months after the completion. The unadjusted men differences were calculated using paired t-test. Adjusted mean difference in outpatient utilization was estimated from a linear regression and inpatient utilization by negative binomial regression adjusting for patient’s age and gender. Results On average, the number of outpatient visits decreased from 8.38 in the year before participants began the program to 7.70 (p=0.04) in the year after they finished the program. In addition, the unadjusted mean number of inpatient admissions per year

  20. Age- and gender-specific epistasis between ADA and TNF-α influences human life-expectancy.

    Science.gov (United States)

    Napolioni, Valerio; Carpi, Francesco M; Giannì, Paola; Sacco, Roberto; Di Blasio, Luca; Mignini, Fiorenzo; Lucarini, Nazzareno; Persico, Antonio M

    2011-11-01

    Aging is a complex phenotype with multiple determinants but a strong genetic component significantly impacts on survival to extreme ages. The dysregulation of immune responses occurring with increasing age is believed to contribute to human morbidity and mortality. Conversely, some genetic determinants of successful aging might reside in those polymorphisms for the immune system genes regulating immune responses. Here we examined the main effects of single loci and multi-locus interactions to test the hypothesis that the adenosine deaminase (ADA) and tumor necrosis factor alpha (TNF-α) genes may influence human life-expectancy. ADA (22G>A, rs73598374) and TNF-α (-308G>A, rs1800629; -238G>A, rs361525) functional SNPs have been determined for 1071 unrelated healthy individuals from Central Italy (18-106 years old) divided into three gender-specific age classes defined according to demographic information and accounting for the different survivals between sexes: for men (women), the first class consists of individuals88 years old (>91 years old). Single-locus analysis showed that only ADA 22G>A is significantly associated with human life-expectancy in males (comparison 1 (age class 2 vs. age class 1), O.R. 1.943, P=0.036; comparison 2 (age class 3 vs. age class 2), O.R. 0.320, P=0.0056). Age- and gender-specific patterns of epistasis between ADA and TNF-α were found using Generalized Multifactor Dimensionality Reduction (GMDR). In comparison 1, a significant two-loci interaction occurs in females between ADA 22G>A and TNF-α -238G>A (Sign Test P=0.011). In comparison 2, both two-loci and three-loci interaction are significant associated with increased life-expectancy over 88 years in males. In conclusion, we report that a combination of functional SNPs within ADA and TNF-α genes can influence life-expectancy in a gender-specific manner and that males and females follow different pathways to attain longevity. Copyright © 2011 Elsevier Ltd. All rights reserved.

  1. Lagu ABC (Ada Banyak Cara Karya Trio Bimbo Dalam Analisis Wacana Michel Foucault

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    Ubaidillah Ubaidillah

    2016-08-01

    Full Text Available This paper examines a song criticizing the phenomenon that occurs in the body of the government of Indonesia nowadays. Lyric of a song ABC (Ada Banyak Cara by Trio Bimbo that becomes the focus of study in this paper is interesting to be studied, considering the Trio Bimbo is famous musicians who focused on religious themes, voicing out his heart in criticizing the government.The discourse theory of Michel Foucault,in which his discourse of language is closely related to who is in power in the region, is used to analyze this song.The result founds that the discourse of language in the ABC song is representation the mercy of the people, in this case represented by Trio Bimbo sound, such as naikkan gaji sendiri, duduk sidang terus mimpi, jaksa hakim wiraswasta, and other discordant expressions that criticize the government. Trio Bimbo does not hesitate to cast his criticism of the government by voicing the discourse of language which is considered as a direct criticism, without the subtle innuendo. If this happens in the Orde Baru era, the discourse of language must be prohibited by the government, because they were in power at that time. However, after the fall of Orde Baru, resime people have the power to create their own linguistic discourse.

  2. ADA Title I allegations and the Mining, Quarrying, and Oil/Gas Extraction industry.

    Science.gov (United States)

    Van Wieren, Todd A; Rhoades, Laura; McMahon, Brian T

    2017-01-01

    The majority of research about employment discrimination in the U.S. Mining, Quarrying, and Oil/Gas (MQOGE) industries has concentrated on gender and race, while little attention has focused on disability. To explore allegations of Americans with Disabilities Act (ADA) Title I discrimination made to the Equal Employment Opportunity Commission (EEOC) by individuals with disabilities against MQOGE employers. Key data available to this study included demographic characteristics of charging parties, size of employers, types of allegations, and case outcomes. Using descriptive analysis, allegation profiles were developed for MQOGE's three main sectors (i.e., Oil/Gas Extraction, Mining except Oil/Gas, and Support Activities). These three profiles where then comparatively analyzed. Lastly, regression analysis explored whether some of the available data could partially predict MQOGE case outcomes. The predominant characteristics of MQOGE allegations were found to be quite similar to the allegation profile of U.S. private-sector industry as a whole, and fairly representative of MQOGE's workforce demographics. Significant differences between MQOGE's three main sector profiles were noted on some important characteristics. Lastly, it was found that MQOGE case outcomes could be partially predicted via some of the available variables. The study's limitations were presented and recommendations were offered for further research.

  3. ADA claim doesn't extend to arbritration clause in union pact.

    Science.gov (United States)

    1998-12-25

    The U.S. Supreme Court ruled unanimously that a collective bargaining agreement's (CBA) general arbitration clause cannot prevent workers from filing claims under the Americans with Disabilities Act (ADA). The ruling was based on the broad language used regarding claims covered by the CBA, and has limited impact. [Name removed], a longshoreman, received workers' compensation and Social Security benefits after an injury. He was prevented from returning to work 3 years later because he had settled a claim for permanent disability. [Name removed] was subject to a CBA that required all disputes to be referred to a grievance procedure. However, rather than follow through with the grievance procedure, he filed a claim in Federal district court. The defendants argued that [name removed]'s failure to file a grievance meant that he was not allowed to file the lawsuit. [Name removed] v. [Name removed] Service Corp. expressly left open the question of whether more specific language regarding claims covered by the CBA can relegate a worker to the arbitration forum.

  4. Fusion of optimized indicators from Advanced Driver Assistance Systems (ADAS) for driver drowsiness detection.

    Science.gov (United States)

    Daza, Iván García; Bergasa, Luis Miguel; Bronte, Sebastián; Yebes, Jose Javier; Almazán, Javier; Arroyo, Roberto

    2014-01-09

    This paper presents a non-intrusive approach for monitoring driver drowsiness using the fusion of several optimized indicators based on driver physical and driving performance measures, obtained from ADAS (Advanced Driver Assistant Systems) in simulated conditions. The paper is focused on real-time drowsiness detection technology rather than on long-term sleep/awake regulation prediction technology. We have developed our own vision system in order to obtain robust and optimized driver indicators able to be used in simulators and future real environments. These indicators are principally based on driver physical and driving performance skills. The fusion of several indicators, proposed in the literature, is evaluated using a neural network and a stochastic optimization method to obtain the best combination. We propose a new method for ground-truth generation based on a supervised Karolinska Sleepiness Scale (KSS). An extensive evaluation of indicators, derived from trials over a third generation simulator with several test subjects during different driving sessions, was performed. The main conclusions about the performance of single indicators and the best combinations of them are included, as well as the future works derived from this study.

  5. Fusion of Optimized Indicators from Advanced Driver Assistance Systems (ADAS for Driver Drowsiness Detection

    Directory of Open Access Journals (Sweden)

    Iván G. Daza

    2014-01-01

    Full Text Available This paper presents a non-intrusive approach for monitoring driver drowsiness using the fusion of several optimized indicators based on driver physical and driving performance measures, obtained from ADAS (Advanced Driver Assistant Systems in simulated conditions. The paper is focused on real-time drowsiness detection technology rather than on long-term sleep/awake regulation prediction technology. We have developed our own vision system in order to obtain robust and optimized driver indicators able to be used in simulators and future real environments. These indicators are principally based on driver physical and driving performance skills. The fusion of several indicators, proposed in the literature, is evaluated using a neural network and a stochastic optimization method to obtain the best combination. We propose a new method for ground-truth generation based on a supervised Karolinska Sleepiness Scale (KSS. An extensive evaluation of indicators, derived from trials over a third generation simulator with several test subjects during different driving sessions, was performed. The main conclusions about the performance of single indicators and the best combinations of them are included, as well as the future works derived from this study.

  6. BASIC CRITERIA OF IRANIAN COMMERCIAL TOOTHPASTES AND AN ADA APPROVED BRAND (CREST

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    N NOUR BAKHSH

    2003-03-01

    Full Text Available Introduction: The effectiveness of fluorided toothpastes in reducing dental caries is well-documented, However not all fluorided toothpastes are equally effective. The objective of this study was to compare some essential criteria of six different toothpastes manufactured in Iran with one brand of ADA approved toothpaste (Crest. Methods. Six commercial toothpastes produced in Iran named as Paveh, Puneh, Nasim, Darugar, golpasand and saviz were compared with Crest in three subjects as follows: 1. Amount of fluoride concentration 2. Amount of releasing fluoride 3. Cleaning efficiency. Two first criteria were tested using the potentiometric method with F- Ion specific electrode, and Cleaning efficiency was done by O'Leary index on 60 volunteers (10 for each toothpaste. Results: Fluoride Concentration in Paveh, Puneh, Nasim toothpastes were nearly700PPM,while in three others were much lower. The highest amount of fluoride was seen in Crest (1450 PPM. Cleaning efficiency of Darugar was better than Crest, Paveh, Puneh. Cleaning efficiency of Nasim was the same as Crest and Golpasand and Saviz were weaker than Crest. Discussion: Since at the present time, the most effective, Cost-benefit method for preventive aspects of fluoride, especially in developing countries is obtained by fluoride toothpastes. Manufactures should improve quality of fluoride toothpastes, ensure that all pates maximize Fluoride bioavailability, develop active agents to help better cleaning efficiency and label products clearly with containig fluoride in PPM.

  7. Fast AdaBoost-Based Face Detection System on a Dynamically Coarse Grain Reconfigurable Architecture

    Science.gov (United States)

    Xiao, Jian; Zhang, Jinguo; Zhu, Min; Yang, Jun; Shi, Longxing

    An AdaBoost-based face detection system is proposed, on a Coarse Grain Reconfigurable Architecture (CGRA) named “REMUS-II”. Our work is quite distinguished from previous ones in three aspects. First, a new hardware-software partition method is proposed and the whole face detection system is divided into several parallel tasks implemented on two Reconfigurable Processing Units (RPU) and one micro Processors Unit (µPU) according to their relationships. These tasks communicate with each other by a mailbox mechanism. Second, a strong classifier is treated as a smallest phase of the detection system, and every phase needs to be executed by these tasks in order. A phase of Haar classifier is dynamically mapped onto a Reconfigurable Cell Array (RCA) only when needed, and it's quite different from traditional Field Programmable Gate Array (FPGA) methods in which all the classifiers are fabricated statically. Third, optimized data and configuration word pre-fetch mechanisms are employed to improve the whole system performance. Implementation results show that our approach under 200MHz clock rate can process up-to 17 frames per second on VGA size images, and the detection rate is over 95%. Our system consumes 194mW, and the die size of fabricated chip is 23mm2 using TSMC 65nm standard cell based technology. To the best of our knowledge, this work is the first implementation of the cascade Haar classifier algorithm on a dynamically CGRA platform presented in the literature.

  8. Predictors of placebo group decline in the Alzheimer's disease Assessment Scale-cognitive subscale (ADAS-Cog) in 24 week clinical trials of Alzheimer's disease.

    Science.gov (United States)

    Irizarry, Michael C; Webb, David J; Bains, Chanchal; Barrett, Steven J; Lai, Robert Y; Laroche, Janette P; Hosford, David; Maher-Edwards, Gareth; Weil, John G

    2008-07-01

    One limitation of several recent 24 week Alzheimer's disease (AD) clinical trials was the lack of cognitive decline detected by the AD Assessment Scale-cognitive subscale (ADAS-cog) in the placebo groups, possibly obscuring true medication effects. Data from 733 individuals in the placebo arms of six AD clinical trials performed 1996-1997 were pooled to examine the relationship of clinical, demographic, and genetic characteristics with the 24 week change in ADAS-cog. Baseline cognitive and functional status and the screening-to-baseline change in ADAS-cog were the strongest independent predictors of the 24 week change in ADAS-cog. The ADAS-cog did not detect progression in patients with mild dementia (screening Mini-Mental State Exam, MMSE, >or=20). The change in ADAS-cog from screening to baseline was inversely correlated with the 24 week change score; it was more difficult to detect cognitive decline at 24 weeks if individuals markedly worsened from screening to baseline. The effects of baseline MMSE and screening-to-baseline change in ADAS-cog generalized to the placebo group (N=106) of another AD study performed in 2004-2005. Overcoming lack of placebo decline in AD clinical trials will require scales more sensitive to cognitive decline in mild AD and strategies to reduce within-person variability in outcome measures.

  9. ADa Compiler Validation Summary Report: Certificate Number 911107W1. 11227 Hewlett-Packard HP 9000 Series 700/800 Ada Compiler, Version 5.35 HP 9000 Series 700 Model 720 = HP 9000 Series 700 Model 720

    Science.gov (United States)

    1991-12-09

    Facility ASLi /SCEL Wright-Patterson AFB OH 45433-6503 92-04471 9 2 2 20 022 Certificate Information The following Ada implementation was tested and...following example illustrates the use of an enumeration representation clause. 4-2 F 4. Type Representation Example type COLOR is (RED, ORANGE , YELLOW...GREEN, AQUA, BLUE, VIOLET); for COLOR use (RED => 10, ORANGE => 20, YELLOW => 40, GREEN => 80, AQUA => 160, 4 BLUE => 320, VIOLET => 640); In the

  10. The clinical meaningfulness of ADAS-Cog changes in Alzheimer's disease patients treated with donepezil in an open-label trial

    Directory of Open Access Journals (Sweden)

    Gorman Mary

    2007-08-01

    Full Text Available Abstract Background In 6-month anti-dementia drug trials, a 4-point change in the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog is held to be clinically important. We examined how this change compared with measures of clinical meaningfulness. Methods This is a secondary analysis of a 12 month open-label study of 100 patients (71 women diagnosed with mild to moderate AD treated with 5–10 mg of donepezil daily. We studied the observed case, 6-month change from baseline on the ADAS-Cog, the Clinician's Interview Based Impression of Change-Plus Caregiver Input (CIBIC-Plus, patient-Goal Attainment Scaling (PGAS and clinician-GAS (CGAS. Results At 6 months, donepezil-treated patients (n = 95 were more likely to show no change (+/- 3 points on the ADAS-Cog (56% than to improve (20% or decline (24% by 4-points. ADAS-Cog change scores were little correlated with other measures: from -0.09 for PGAS to 0.27 for the CIBIC-Plus. While patients who improved on the ADAS-Cog were less likely to decline on the clinical measures (26%, 43% of patients who declined on the ADAS-Cog improved on at least two of the clinical measures. Conclusion The ADAS-Cog did not capture all clinically important effects. In general, ADAS-Cog improvement indicates clinical improvement, whereas many people with ADAS-Cog decline do not show clinical decline. The open-label design of this study does not allow us to know whether this is a treatment effect, which requires further investigation.

  11. The clinical meaningfulness of ADAS-Cog changes in Alzheimer's disease patients treated with donepezil in an open-label trial.

    Science.gov (United States)

    Rockwood, Kenneth; Fay, Sherri; Gorman, Mary; Carver, Daniel; Graham, Janice E

    2007-08-30

    In 6-month anti-dementia drug trials, a 4-point change in the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) is held to be clinically important. We examined how this change compared with measures of clinical meaningfulness. This is a secondary analysis of a 12 month open-label study of 100 patients (71 women) diagnosed with mild to moderate AD treated with 5-10 mg of donepezil daily. We studied the observed case, 6-month change from baseline on the ADAS-Cog, the Clinician's Interview Based Impression of Change-Plus Caregiver Input (CIBIC-Plus), patient-Goal Attainment Scaling (PGAS) and clinician-GAS (CGAS). At 6 months, donepezil-treated patients (n = 95) were more likely to show no change (+/- 3 points) on the ADAS-Cog (56%) than to improve (20%) or decline (24%) by 4-points. ADAS-Cog change scores were little correlated with other measures: from -0.09 for PGAS to 0.27 for the CIBIC-Plus. While patients who improved on the ADAS-Cog were less likely to decline on the clinical measures (26%), 43% of patients who declined on the ADAS-Cog improved on at least two of the clinical measures. The ADAS-Cog did not capture all clinically important effects. In general, ADAS-Cog improvement indicates clinical improvement, whereas many people with ADAS-Cog decline do not show clinical decline. The open-label design of this study does not allow us to know whether this is a treatment effect, which requires further investigation.

  12. Microevolution of the chromosomal region of acute disease antigen A (adaA in the query (Q fever agent Coxiella burnetii.

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    Dimitrios Frangoulidis

    Full Text Available The acute disease antigen A (adaA gene is believed to be associated with Coxiella burnetii strains causing acute Q fever. The detailed analysis of the adaA genomic region of 23 human- and 86 animal-derived C. burnetii isolates presented in this study reveals a much more polymorphic appearance and distribution of the adaA gene, resulting in a classification of C. burnetii strains of better differentiation than previously anticipated. Three different genomic variants of the adaA gene were identified which could be detected in isolates from acute and chronic patients, rendering the association of adaA positive strains with acute Q fever disease disputable. In addition, all adaA positive strains in humans and animals showed the occurrence of the QpH1 plasmid. All adaA positive isolates of acute human patients except one showed a distinct SNP variation at position 431, also predominant in sheep strains, which correlates well with the observation that sheep are a major source of human infection. Furthermore, the phylogenetic analysis of the adaA gene revealed three deletion events and supported the hypothesis that strain Dugway 5J108-111 might be the ancestor of all known C. burnetii strains. Based on our findings, we could confirm the QpDV group and we were able to define a new genotypic cluster. The adaA gene polymorphisms shown here improve molecular typing of Q fever, and give new insights into microevolutionary adaption processes in C. burnetii.

  13. Using naturalistic driving films as a design tool for investigating driver requirements in HMI design for ADAS.

    Science.gov (United States)

    Wang, Minjuan; Sun, Dong; Chen, Fang

    2012-01-01

    In recent years, there are many naturalistic driving projects have been conducted, such as the 100-Car Project (Naturalistic Driving study in United State), EuroFOT(European Large-Scale Field Operational Tests on Vehicle Systems), SeMi- FOT(Sweden Michigan Naturalistic Field Operational Test and etc. However, those valuable naturalistic driving data hasn't been applied into Human-machine Interaction (HMI) design for Advanced Driver Assistance Systems (ADAS), a good HMI design for ADAS requires a deep understanding of drive environment and the interactions between the driving car and other road users in different situations. The results demonstrated the benefits of using naturalistic driving films as a mean for enhancing focus group discussion for better understanding driver's needs and traffic environment constraints. It provided an efficient tool for designers to have inside knowledge about drive and the needs for information presentation; The recommendations for how to apply this method is discussed in the paper.

  14. Characteristic deterioration of ADAS-Jcog subscale scores and correlations with regional cerebral blood flow reductions in Alzheimer's disease.

    Science.gov (United States)

    Yoshii, Fumihito; Kawaguchi, Chikako; Kohara, Saori; Shimizu, Mie; Onaka, Hiroe; Ryo, Masafuchi; Takahashi, Wakoh

    2018-05-01

    The Alzheimer Disease Assessment Scale (Japanese version) cognitive subscale (ADAS-Jcog) is composed of a number of subscale tasks. However, it is not clear which subscale tasks are most susceptible to impairment in Alzheimer's disease (AD) or what is the relationship between reduction in regional cerebral blood flow (rCBF) and decreased ADAS-Jcog scores. Subjects were 32 AD patients, aged 52-86 years. We examined the relationship between subscale tasks that showed marked score changes and brain regions that showed reduced rCBF over a 2-year period. rCBF was measured by single-photon emission computed tomography (SPECT) with technetium-99m ethyl cysteinate dimer ( 99m Tc-ECD), and the SPECT imaging data were analyzed with the easy Z-score imaging system (eZIS) and voxel-based stereotactic extraction estimation (vbSEE) methods. Total score of ADAS-Jcog deteriorated from 19.5 ± 7.0 to 35.7 ± 15.2 after 2 years. Subscale scores were significantly worse in all fields, particularly in orientation, word recall, remembering test instructions, commands, constructional praxis, and ideational praxis, in that order. Significant correlations were found between (1) word recall and commands and rCBF in the left middle temporal lobe, (2) naming objects/fingers and rCBF in the left temporal (middle, inferior) lobe, and (3) constructional and ideational praxis and rCBF in the right parietal (superior, inferior) lobe, temporal (superior, middle) lobe, angular gyrus, and cingulate gyrus. We identified the brain regions associated with specifically impaired subscales of ADAS-Jcog during progressive deterioration of AD over 2 years.

  15. Near infrared organic light-emitting diodes based on acceptor-donor-acceptor (ADA) using novel conjugated isatin Schiff bases

    International Nuclear Information System (INIS)

    Taghi Sharbati, Mohammad; Soltani Rad, Mohammad Navid; Behrouz, Somayeh; Gharavi, Alireza; Emami, Farzin

    2011-01-01

    Fabrications of a single layer organic light emitting diodes (OLEDs) based on two conjugated acceptor-donor-acceptor (ADA) isatin Schiff bases are described. The electroluminescent spectra of these materials range from 630 to 700 nm and their band gaps were measured between 1.97 and 1.77 eV. The measured maximum external quantum efficiencies (EQE) for fabricated OLEDs are 0.0515% and 0.054% for two acceptor-donor-acceptor chromophores. The Commission International De L'Eclairage (CIE) (1931) coordinates of these two compounds were attained and found to be (0.4077, 0.4128) and (0.4411, 0.4126) for two used acceptor-donor-acceptor chromophores. The measured I-V curves demonstrated the apparent diode behavior of two ADA chromophores. The turn-on voltages in these OLEDs are directly dependent on the thickness. These results have demonstrated that ADA isatin Schiff bases could be considered as promising electroluminescence-emitting materials for fabrication of OLEDs.

  16. Using Vertical Electrical Soundings for Characterizing Hydrogeological and Tectonic Settings in Deir El-Adas Area, Yarmouk Basin, Syria

    Science.gov (United States)

    Al-Fares, Walid

    2016-06-01

    The present study is aimed at characterizing the subsurface geological and tectonic structure in Deir El-Adas area, by using Vertical Electrical Sounding survey (VES) and hydrogeological investigations, in order to determine the causes of the failure for the majority of the wells drilled in the area. The survey data was treated in three different approaches including direct VES inversion, pseudo-2D method and horizontal profiling, in order to maximize the reliability of the data interpretation. The results revealed the presence of a local faulted anticline structure at the top of the Paleogene formation, underneath the basaltic outcrops where Deir El-Adas village is situated. The appearance of this subsurface anticline structure has complicated the local hydro-geological situation, and most likely led to limitation of the groundwater recharge in the area. Moreover, the performed piezometric and discharge maps indicated the presence of a notable groundwater watershed, in addition to feeble water productivity of the wells drilled adjacent to Deir El-Adas, mostly related to the subsurface geological and tectonic settings in the area.

  17. Flow and linear coefficient of thermal expansion of four types of Base Plate waxes compared with ADA standard

    Directory of Open Access Journals (Sweden)

    Monzavi A

    2002-07-01

    Full Text Available Waxes have a lot of applications in dentistry. Such materials are of thermoplastic type that undergoes deformation in different temperatures. Two important properties of base plate waxes are flow and their coefficient of linear thermal expansion. Recently, different institutions, inside the country, produce dentistry waxes, while they have not been standardized. Consequently, consumers' dissatisfaction are observed. In this research, the two above- mentioned factors were compared between three kinds of Iranian waxes with Cavex that is foreign production, based on test number 24 of ADA. To measure the flow rate in the temperatures of 23, 37 and 45°c, Wilcoxon statistical analysis was used. The results showed that in 23°c, the flow rate of Cavex and Azardent waxes met ADA standards; however, it was not true for two others types. In 37°c, the flow of none of the waxes was standardized and in 45°c their flow was acceptable, moreover, thermal expansion coefficient, for Cavex and Azardent types, was based on ADA standard.

  18. Estruturas de concreto reforçadas com PRFC Parte II: análise dos modelos de cisalhamento

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    A. L. Gamino

    Full Text Available Este artigo corresponde à segunda parte de trabalho visando à avaliação de modelos de projeto de estruturas de concreto armado reforçadas com Polímeros Reforçados com Fibras de Carbono (PRFC. São avaliados modelos de cisalhamento correspondentes às recomendações ACI-440 e fib-14, além de outros modelos mais recentes, disponíveis na literatura. Esses modelos foram aplicados na análise de oito vigas "T" reforçadas ao cisalhamento com tiras de PRFC. Diferentes tipos de compósitos de fibras de carbono (tecidos e laminados disponíveis no mercado brasileiro, de diferentes fabricantes, foram aplicados neste estudo. Os resultados obtidos indicam um ganho de capacidade resistente e ductilidade das vigas reforçadas, a partir do mecanismo de ancoragem usado nas tiras de PRFC, e que nenhum dos modelos analíticos testados foi capaz de reproduzir satisfatoriamente o comportamento estrutural observado nos experimentos.

  19. An improved gravity compensation method for high-precision free-INS based on MEC–BP–AdaBoost

    International Nuclear Information System (INIS)

    Zhou, Xiao; Yang, Gongliu; Wang, Jing; Li, Jing

    2016-01-01

    In recent years, with the rapid improvement of inertial sensors (accelerometers and gyroscopes), gravity compensation has become more important for improving navigation accuracy in inertial navigation systems (INS), especially for high-precision INS. This paper proposes a mind evolutionary computation (MEC) back propagation (BP) AdaBoost algorithm neural-network-based gravity compensation method that estimates the gravity disturbance on the track based on measured gravity data. A MEC–BP–AdaBoost network-based gravity compensation algorithm used in the training process to establish the prediction model takes the carrier position (longitude and latitude) provided by INS as the input data and the gravity disturbance as the output data, and then compensates the obtained gravity disturbance into the INS’s error equations to restrain the position error propagation. The MEC–BP–AdaBoost algorithm can not only effectively avoid BP neural networks being trapped in local extrema, but also perfectly solve the nonlinearity between the input and output data that cannot be solved by traditional interpolation methods, such as least-square collocation (LSC) interpolation. The accuracy and feasibility of the proposed interpolation method are verified through numerical tests. A comparison of several other compensation methods applied in field experiments, including LSC interpolation and traditional BP interpolation, highlights the superior performance of the proposed method. The field experiment results show that the maximum value of the position error can reduce by 28% with the proposed gravity compensation method. (paper)

  20. The Spt-Ada-Gcn5 Acetyltransferase (SAGA complex in Aspergillus nidulans.

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    Paraskevi Georgakopoulos

    Full Text Available A mutation screen in Aspergillus nidulans uncovered mutations in the acdX gene that led to altered repression by acetate, but not by glucose. AcdX of A. nidulans is highly conserved with Spt8p of Saccharomyces cerevisiae, and since Spt8p is a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA complex, the SAGA complex may have a role in acetate repression in A. nidulans. We used a bioinformatic approach to identify genes encoding most members of the SAGA complex in A. nidulans, and a proteomic analysis to confirm that most protein components identified indeed exist as a complex in A. nidulans. No apparent compositional differences were detected in mycelia cultured in acetate compared to glucose medium. The methods used revealed apparent differences between Yeast and A. nidulans in the deubiquitination (DUB module of the complex, which in S. cerevisiae consists of Sgf11p, Sus1p, and Ubp8p. Although a convincing homologue of S. cerevisiae Ubp8p was identified in the A. nidulans genome, there were no apparent homologues for Sus1p and Sgf11p. In addition, when the SAGA complex was purified from A. nidulans, members of the DUB module were not co-purified with the complex, indicating that functional homologues of Sus1p and Sgf11p were not part of the complex. Thus, deubiquitination of H2B-Ub in stress conditions is likely to be regulated differently in A. nidulans compared to S. cerevisiae.

  1. Diagnostic value of combined determination of serum and chest fluid adenosine deaminase (ADA), IL-2, IL-6, IL-10 contents for differentiation of tuberculous from malignant pleural effusion

    International Nuclear Information System (INIS)

    Wu Jiaming; Wang Limin

    2005-01-01

    Objective: To investigate the possible diagnostic value of combined determination of serum and chest fluid contents of ADA, IL-2, IL-6, IL-10 in patients with tuberculous and malignant pleural effusion. Methods: Serum and chest fluid ADA (with biochemical method), IL-2, IL-6, IL-10 (with ELISA) contents were measured in 56 patients with tuberculosis pleural effusion, 53 patients with malignant effusion and 30 controls (in serum only). The receiving operative characteristic (ROC) curve for each parameter was analyzed for study of respective area under curse (Auc). Results: The serum IL-6 levels in both groups of patients were significantly higher than those in the controls (P<0.05). The chest fluid contents of ADA, IL-2, IL-6 and IL-10 in patients with tuberculous effusion were all significantly higher than those in patients with malignancies (P<0.05). The Auc in the ROC was largest in the case of ADA, followed by IL-10, IL-6 with IL-2 the least. Conclusion: Determination of chest fluid ADA, IL-2, IL-6, IL-10 contents was helpful in the differentiation of tuberculous from malignant pleural effusion. Combined determination of chest fluid ADA and IL-10 provided the highest accuracy rate for differentional diagnosis. (authors)

  2. ESTRUCTURA ESPACIAL DE Pachycereus weberi (Coult. Backeb. EN LA CAÑADA DEL ZOPILOTE, GUERRERO

    Directory of Open Access Journals (Sweden)

    Blanca Estela Linzaga-Román

    2011-01-01

    Full Text Available El propósito del presente estudio fue evaluar la estructura poblacional de Pachycereus weberi en la Cañada del Zopilote, Guerrero, México. Se estableció una parcela de observación de 50 x 50 m (2,500 m², dividida en cuadros de 10 x 10 m para facilitar el levantamiento de la información de campo. Todos los individuos de P. weberi con altura > 0.10 m se marcaron, se les midió la altura total y Diámetro Normal (DN, y se ubicaron por sus coordenadas X y Y. Además, todos los individuos de las especies leñosas asociadas con DN > 5 cm, se marcaron, se identificaron y se les registró su diámetro, y coordenadas X y Y. Se determinó el índice de distribución y correlación espacial de individuos de P. weberi, divididos en dos estadios de desarrollo, juveniles y adultos, a través del índice de Ripley. Se registraron un total de 18 especies, asociadas a P. weberi. El mayor índice de Valor de Importancia Relativa lo registró P. weberi con 41.1 %, seguido de Acacia tenciifolia con 22.6 %. Se encontraron individuos de P. weberi con más de 8.5 m de altura y diámetros desde 5 a 43.8 cm. El patrón de distribución espacial fue de forma agregada tanto para individuos en periodo de desarrollo juvenil como adulto. La correlación espacial de ambos estadios de desarrollo fue de repulsión en distancias de 2 a 13 m. La distribución diamétrica encontrada sugiere un reclutamiento de nuevos individuos a la población de tipo episódico. Es decir, existen pocas incorporaciones en tamaños intermedios entre juveniles y adultos.

  3. Calçada da fome: sobre os anjos e os mortos no Passeio da Glória

    OpenAIRE

    Caminha, José Guimarães; UERJ

    2017-01-01

    Resumo: Nesta reflexão sobre ontologias visuais, transita-se entre as fotografias antigas de pessoas provavelmente já mortas e o mercado vivo das ruas do Rio de Janeiro, notadamente no bairro da Glória, onde se observa o trabalho dos trapeiros numa área conhecida como “calçada da fome”. É nesse espaço intertextual/intermidial que a cidade transforma-se num palco no qual se descortinam os modos de sobrevivência do flâneur e do passante, do trapeiro e do colecionador, e de tantos outros persona...

  4. Vigas de concreto reforçadas com bambu Dendrocalamus giganteus. II: modelagem e critérios de dimensionamento

    OpenAIRE

    Lima Júnior,Humberto C.; Willrich,Fábio L.; Fabro,Gilmar

    2005-01-01

    Este trabalho corresponde à segunda parte de uma publicação sobre o comportamento estrutural de vigas de concreto reforçadas com bambu, na qual se apresenta e discute a modelagem dessas estruturas para, em seguida, serem apresentadas sugestões e hipóteses para o dimensionamento desses elementos estruturais. Para tanto, utilizou-se um modelo computacional baseado no Método dos Elementos Finitos, ao qual foram incorporadas sub-rotinas com as leis constitutivas do bambu e do concreto. Para calib...

  5. Formulação de um indicador de acessibilidade das calçadas e travessias

    Directory of Open Access Journals (Sweden)

    Celso Luiz Guimarães Keppe Junior

    2008-12-01

    Full Text Available O presente trabalho visa definir uma forma fácil e prática de avaliar-se o nível de serviço dos espaços públicos destinados às pessoas com deficiência física (calçadas e travessias de ruas pela determinação de um índice que considere os parâmetros de maior importância sob o ponto de vista dos usuários de cadeira de rodas. O índice é definido com a identificação e a ordenação de variáveis de caracterização física e ambiental das calçadas relacionadas aos aspectos de qualidade de conforto, segurança e condições do ambiente. A ponderação das variáveis de caracterização física e ambiental das calçadas (grau de importância é realizada por análise da percepção dos usuários de cadeira de rodas, definindo-se, dessa forma, o Índice de Acessibilidade das Calçadas e Travessias - IACT, e verificando sua funcionalidade por auditoria realizada com auxílio, também, de usuários de cadeira de rodas selecionados para realizar testes em dois locais da cidade de São Carlos. Munidos dessa ferramenta de avaliação, os órgãos de gestão viária podem avaliar a qualidade dos espaços públicos em uma rota total ou em trechos específicos dos deslocamentos imprescindíveis para a real participação da pessoa com dificuldade de locomoção na sociedade.

  6. Comportamento estrutural de vigas de concreto reforçadas com ripas de bambu cravejadas de pinos

    OpenAIRE

    Braga Filho,Antonio C.; Lima Júnior,Humberto C.; Barbosa,Normando P.; Willrich,Fabio L.

    2010-01-01

    Uma das deficiências do bambu reforçando vigas de concreto armado está relacionada com deslocamentos relativos entre os dois materiais. A investigação aqui reportada teve como objetivo avaliar experimentalmente a possibilidade de se melhorar o trabalho conjunto bambu-concreto, através do cravejamento de pinos nas ripas de bambu usadas como reforço. Para tanto, oito vigas de concreto foram ensaiadas, das quais seis foram reforçadas com ripas de bambu Dendrocalamus giganteus Munro cravejadas de...

  7. Relationships between cognitive impairment on ADAS-cog and regional cerebral blood flow using SPECT in late-onset Alzheimer's disease.

    Science.gov (United States)

    Takahashi, Michio; Oda, Yasunori; Okubo, Toshiyuki; Shirayama, Yukihiko

    2017-09-01

    The aim of this study was to examine brain hypoperfusion and its relationship with cognitive dysfunction in late-onset Alzheimer's disease (AD). Forty patients with late-onset AD and not receiving acetylcholinesterase inhibitors were recruited from outpatient clinics. We examined cognitive function using the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) and brain perfusion using single-photon emission computed tomography, and analyzed classified gyrus level segments with three-dimensional stereotactic surface projection and the stereotactic extraction estimation method level 3. ADAS-cog subscales were grouped into three domains: language, memory, and praxis. Patients with late-onset AD showed an apparent reduction in regional cerebral blood flow (rCBF) with a z score >1.5 in the frontal, temporal, and limbic lobes, with lesser reduction in the parietal and occipital lobes. Although hypoperfusion in the orbital, rectal, and subcallosal gyri of the frontal lobe was prominent, rCBF in the inferior frontal gyrus of the frontal lobe was significantly correlated with ADAS-cog total and language and praxis subscale scores. The parahippocampal gyrus of the limbic lobe was also significantly correlated with the ADAS-cog total, language, and praxis subscale scores. Additionally, the cingulate of the limbic lobe was significantly related with ADAS-cog memory. In spite of lesser hypoperfusion, the posterior cingulate gyrus of the limbic lobe was significantly related with ADAS-cog total, language, and memory subscale scores. Further, each subdivision of ADAS-cog was found to be related with various brain regions.

  8. Modeling and Implementing Two-Stage AdaBoost for Real-Time Vehicle License Plate Detection

    Directory of Open Access Journals (Sweden)

    Moon Kyou Song

    2014-01-01

    Full Text Available License plate (LP detection is the most imperative part of the automatic LP recognition system. In previous years, different methods, techniques, and algorithms have been developed for LP detection (LPD systems. This paper proposes to automatical detection of car LPs via image processing techniques based on classifier or machine learning algorithms. In this paper, we propose a real-time and robust method for LPD systems using the two-stage adaptive boosting (AdaBoost algorithm combined with different image preprocessing techniques. Haar-like features are used to compute and select features from LP images. The AdaBoost algorithm is used to classify parts of an image within a search window by a trained strong classifier as either LP or non-LP. Adaptive thresholding is used for the image preprocessing method applied to those images that are of insufficient quality for LPD. This method is of a faster speed and higher accuracy than most of the existing methods used in LPD. Experimental results demonstrate that the average LPD rate is 98.38% and the computational time is approximately 49 ms.

  9. Supervised retinal vessel segmentation from color fundus images based on matched filtering and AdaBoost classifier.

    Directory of Open Access Journals (Sweden)

    Nogol Memari

    Full Text Available The structure and appearance of the blood vessel network in retinal fundus images is an essential part of diagnosing various problems associated with the eyes, such as diabetes and hypertension. In this paper, an automatic retinal vessel segmentation method utilizing matched filter techniques coupled with an AdaBoost classifier is proposed. The fundus image is enhanced using morphological operations, the contrast is increased using contrast limited adaptive histogram equalization (CLAHE method and the inhomogeneity is corrected using Retinex approach. Then, the blood vessels are enhanced using a combination of B-COSFIRE and Frangi matched filters. From this preprocessed image, different statistical features are computed on a pixel-wise basis and used in an AdaBoost classifier to extract the blood vessel network inside the image. Finally, the segmented images are postprocessed to remove the misclassified pixels and regions. The proposed method was validated using publicly accessible Digital Retinal Images for Vessel Extraction (DRIVE, Structured Analysis of the Retina (STARE and Child Heart and Health Study in England (CHASE_DB1 datasets commonly used for determining the accuracy of retinal vessel segmentation methods. The accuracy of the proposed segmentation method was comparable to other state of the art methods while being very close to the manual segmentation provided by the second human observer with an average accuracy of 0.972, 0.951 and 0.948 in DRIVE, STARE and CHASE_DB1 datasets, respectively.

  10. Adaptable dialog architecture and runtime engine (AdaRTE): a framework for rapid prototyping of health dialog systems.

    Science.gov (United States)

    Rojas-Barahona, L M; Giorgino, T

    2009-04-01

    Spoken dialog systems have been increasingly employed to provide ubiquitous access via telephone to information and services for the non-Internet-connected public. They have been successfully applied in the health care context; however, speech technology requires a considerable development investment. The advent of VoiceXML reduced the proliferation of incompatible dialog formalisms, at the expense of adding even more complexity. This paper introduces a novel architecture for dialogue representation and interpretation, AdaRTE, which allows developers to lay out dialog interactions through a high-level formalism, offering both declarative and procedural features. AdaRTE's aim is to provide a ground for deploying complex and adaptable dialogs whilst allowing experimentation and incremental adoption of innovative speech technologies. It enhances augmented transition networks with dynamic behavior, and drives multiple back-end realizers, including VoiceXML. It has been especially targeted to the health care context, because of the great scale and the need for reducing the barrier to a widespread adoption of dialog systems.

  11. Synthesis of an A-D-A type of molecule used as electron acceptor for improving charge transfer in organic solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Chao-Zhi, E-mail: chzhzhang@sohu.com [Department of Chemistry, Nanjing University of Information Science & Technology, Nanjing 210044 (China); Gu, Shu-Duo; Shen, Dan; Yuan, Yang [Department of Chemistry, Nanjing University of Information Science & Technology, Nanjing 210044 (China); Zhang, Mingdao, E-mail: matchlessjimmy@163.com [Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control, Nanjing University of Information Science & Technology, Nanjing 210044 (China)

    2016-08-22

    Electron-accepting molecules play an important role in developing organic solar cells. A new type of A-D-A molecule, 3,6-di([7-(5-bromothiophen-2-yl)-1,5,2,4,6,8-dithiotetrazocin-3-yl]thiophen -2-yl)-9-(2-ethylhexyl)carbazole, was synthesized. The lowest unoccupied molecular orbital (LUMO) and highest occupied molecular orbital (HOMO) energy levels are −3.55 and −5.85 eV, respectively. Therefore, the A-D-A type of compound could be used as electron acceptor for fabricating organic solar cell with a high open circuit voltage. Gibbs free energy (−49.2 kJ/mol) reveals that the process of A-D-A acceptor accepting an electron from poly(3-hexylthiophene) at excited state is spontaneous. The value of entropy (118 J/mol) in the process of an electron transferring from P3HT to the A-D-A acceptor at organic interface suggests that electrons generated from separation of electron-hole pairs at donor/acceptor interface would be delocalized efficiently. Therefore, the A-D-A molecule would be a potential acceptor for efficient organic BHJ solar cells.

  12. One-year treatment of Alzheimer's disease with acetylcholinesterase inhibitors: improvement on ADAS-cog and TMT A, no change or worsening on other tests.

    Science.gov (United States)

    Borkowska, Alina; Ziolkowska-Kochan, Marzena; Rybakowski, Janusz K

    2005-08-01

    The aim of this study was to assess cognitive functioning measured by selected psychometric and neuropsychological tools in patients with Alzheimer's disease (AD) after 1-year treatment with acetylcholinesterase inhibitors. Seventy-six patients (22 male and 54 female) with a mild to moderate stage of AD, aged 56-86 (mean 68) years, were treated. Forty-seven received donepezil (mean dose 9.3 mg/d) and 29 rivastigmine (mean dose 8.5 mg/d). Cognitive measurements included: the mini mental state examination (MMSE), the Alzheimer disease assessment scale-cognitive (ADAS- cog), the trail making test (TMT) and the Stroop color word interference test. The assessments were made before and after 3, 6 and 12 months of treatment. A significant improvement in ADAS-cog (p ADAS-cog) and psychomotor speed (TMT A), however, such treatment is unable to prevent the deterioration of working memory and executive functions. Copyright (c) 2005 John Wiley & Sons, Ltd.

  13. Validation study of the Alzheimer's disease assessment scale-cognitive subscale (ADAS-Cog) for the Portuguese patients with mild cognitive impairment and Alzheimer's disease.

    Science.gov (United States)

    Nogueira, Joana; Freitas, Sandra; Duro, Diana; Almeida, Jorge; Santana, Isabel

    2018-03-23

    The Alzheimer's disease assessment scale-Cognitive Subscale (ADAS-Cog) is a battery to assess cognitive performance in Alzheimer's disease (AD) and was developed according to the core characteristics of cognitive decline in AD: memory, language, praxis, constructive ability, and orientation. The aim of this study was to explore the diagnostic accuracy and discriminative capacity of the ADAS-Cog for Mild Cognitive Impairment (MCI) and AD, using cut-off points for the Portuguese population. The European Portuguese version of the ADAS-Cog was administrated to 650 participants, divided into a control group (n = 210), an MCI group (n = 240), and an AD group (n = 200). The clinical groups fulfilled standard international diagnostic criteria. Controls were healthy cognitive participants actively integrated in the community. The neuropsychological assessment protocol included the ADAS-Cog, the Mini Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), and the Adults and Older Adults Functional Assessment Inventory (IAFAI). The ADAS-Cog revealed good psychometric indicators, and the total scores were significantly different between the three groups (p  9 points (AUC = .835; sensitivity = 58% and specificity = 91%) and AD > 12 points (AUC = .996; sensitivity = 94% and specificity = 98%). Our findings confirmed the capacity of the ADAS-Cog total score to identify cognitive impairment in AD patients, with poor sensitivity for MCI, in a Portuguese cohort.

  14. Perbedaan Daya Hambat Bakteri dari Propolis Cair yang Ada di Pasaran Terhadap Escherichia Coli dan Staphylococcus Aureus Secara In Vitro

    Directory of Open Access Journals (Sweden)

    Bangun Azhari Yusuf

    2015-09-01

    Full Text Available Abstrak Propolis adalah zat yang digunakan lebah melindungi sarangnya dari berbagai ancaman. Komponen utama propolis adalah resin yang dikumpulkan lebah dan dicampur dengan air liurnya. Manusia juga menggunakan propolis sebagai obat berbagai penyakit, seperti infeksi bakteri. Propolis memiliki kemampuan antibakteri terhadap Escherichiacoli dan Staphylococcus aureus. Kualitas dan jenis propolis sesuai dengan komposisi kimia, iklim dan tempat berkembang biak. Tujuan penelitian ini adalah melihat perbedaan daya hambat bakteri Propolis cair 1 dan Propolis cair 2 yang ada di pasaran terhadap Escherichia coli dan Staphylococcus aureus secara in vitro. Propolis yang akan diuji adalah propolis cair yang ada di pasaran dipilih dua secara acak. Penelitian dilaksanakan pada bulan Januari 2013 di laboratorium Mikrobiologi Fakultas Kedokteran Universitas Andalas. Jenis penelitian eksperimentalmenggunakan metode difusi (metode cakram dan analitik dengan menghubungkan perbedaan kedua propolis sebagai antibakteri. Hasil penelitian ini menunjukkan propolis cair 1 dan propolis cair 2 yang ada di pasaran tidak memiliki efek antibakteri terhadap Escherichia coli dan terdapat perbedaan daya hambat bakteri dari kedua propolisterhadap Staphylococcus aureus. Propolis cair 2 (diklaim berasal dari Selandia baru memiliki daya hambat bakteri yang lebih baik daripada propolis cair 1 (diklaim berasal dari Malaysia.Kata kunci: propolis cair, perbedaan daya hambat bakteri, Escherichia coli, Staphylococcus aureusAbstract Propolis is substance which use to protect bee hive from various threat. The main component of propolis is resin which is collected and mixed with saliva. The human also use propolis as a treatment against various illness such as bacterial infection. Propolis has an antibacterial effect to Escherichia coli and Stahpylococcus aureus. The quality and type of propolis is also in accordance with chemical composition, climate and their breeding location. The

  15. [Validation of the Hungarian version of Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) in patients with mild cognitive impairment].

    Science.gov (United States)

    Papp, Edina; Pákáski, Magdolna; Drótos, Gergely; Kálmán, János

    2012-01-01

    Early recognition of mild cognitive impairment (MCI) has increasing clinical relevance in the treatment process of dementia, since it is considered as prodromal period. A great variety of instruments have been developed for measuring cognitive performance of the demented patients. The cognitive subscale of the Alzheimer's Disease Assessment Scale (ADAS-Cog) is one of the most frequently applied instrument to determine the severity of dementia and the efficiency of pharmacotherapy. The aim of this study is to examine the sensitivity parameters of the Hungarian ADAS-Cog in differentiating healthy elderly from MCI patients, furthermore to compare the sociodemographic data of the two groups. Fourty-five patients with MCI and 47 healthy subjects (HS) participated in the study. Their age variated between 52 and 88 years, the mean age was 68.8 (standard deviation=8.6). The mean of the years of education was 11.8 (standard deviation=3.5). Mental state was determined by ADAS-Cog and Mini-Mental State Examination (MMSE) and Beck Depression Inventory (BDI) was used to exclude depression. Data analysis was performed with SPSS 17. There were no significant differences between the two groups considering the sociodemographic data. The total score of ADAS-Cog is the most sensitive index (AUC: 0.875, sensitivity: 95.6%) for determining MCI, although the ratio of false positive cases was very high (specificity: 70.2%). The cut-off scores of the ADAS-Cog in the Hungarian sample were higher than the findings in previous researches. Positive correlation between age and ADAS-Cog total score was only significant in the HS group. On the other hand, negative correlation was found between education and ADAS-Cog total score in the MCI group. These results indicate that the currently used Hungarian ADAS-Cog is able to distinguish between MCI patients and HS groups. However, the adaptation of the Hungarian version will be necessary during the further standardization process including the

  16. Structural zinc(II thiolate complexes relevant to the modeling of Ada repair protein: Application toward alkylation reactions

    Directory of Open Access Journals (Sweden)

    Mohamed M. Ibrahim

    2014-11-01

    Full Text Available The TtZn(II-bound perchlorate complex [TtZn–OClO3] 1 (Ttxyly = hydrotris[N-xylyl-thioimidazolyl]borate was used for the synthesis of zinc(II-bound ethanthiothiol complex [TtZn–SCH2CH3] 2 and its hydrogen-bond containing analog Tt–ZnSCH2CH2–NH(COOC(CH33 3. These thiolate complexes were examined as structural models for the active sites of Ada repair protein toward methylation reactions. The Zn[S3O] coordination sphere in complex 1 includes three thione donors from the ligand Ttixyl and one oxygen donor from the perchlorate coligand in ideally tetrahedral arrangement around the zinc center. The average Zn(1–S(thione bond length is 2.344 Å, and the Zn(1–O(1 bond length is 1.917 Å.

  17. Robust Grape Cluster Detection in a Vineyard by Combining the AdaBoost Framework and Multiple Color Components

    Science.gov (United States)

    Luo, Lufeng; Tang, Yunchao; Zou, Xiangjun; Wang, Chenglin; Zhang, Po; Feng, Wenxian

    2016-01-01

    The automatic fruit detection and precision picking in unstructured environments was always a difficult and frontline problem in the harvesting robots field. To realize the accurate identification of grape clusters in a vineyard, an approach for the automatic detection of ripe grape by combining the AdaBoost framework and multiple color components was developed by using a simple vision sensor. This approach mainly included three steps: (1) the dataset of classifier training samples was obtained by capturing the images from grape planting scenes using a color digital camera, extracting the effective color components for grape clusters, and then constructing the corresponding linear classification models using the threshold method; (2) based on these linear models and the dataset, a strong classifier was constructed by using the AdaBoost framework; and (3) all the pixels of the captured images were classified by the strong classifier, the noise was eliminated by the region threshold method and morphological filtering, and the grape clusters were finally marked using the enclosing rectangle method. Nine hundred testing samples were used to verify the constructed strong classifier, and the classification accuracy reached up to 96.56%, higher than other linear classification models. Moreover, 200 images captured under three different illuminations in the vineyard were selected as the testing images on which the proposed approach was applied, and the average detection rate was as high as 93.74%. The experimental results show that the approach can partly restrain the influence of the complex background such as the weather condition, leaves and changing illumination. PMID:27973409

  18. Robust Grape Cluster Detection in a Vineyard by Combining the AdaBoost Framework and Multiple Color Components

    Directory of Open Access Journals (Sweden)

    Lufeng Luo

    2016-12-01

    Full Text Available The automatic fruit detection and precision picking in unstructured environments was always a difficult and frontline problem in the harvesting robots field. To realize the accurate identification of grape clusters in a vineyard, an approach for the automatic detection of ripe grape by combining the AdaBoost framework and multiple color components was developed by using a simple vision sensor. This approach mainly included three steps: (1 the dataset of classifier training samples was obtained by capturing the images from grape planting scenes using a color digital camera, extracting the effective color components for grape clusters, and then constructing the corresponding linear classification models using the threshold method; (2 based on these linear models and the dataset, a strong classifier was constructed by using the AdaBoost framework; and (3 all the pixels of the captured images were classified by the strong classifier, the noise was eliminated by the region threshold method and morphological filtering, and the grape clusters were finally marked using the enclosing rectangle method. Nine hundred testing samples were used to verify the constructed strong classifier, and the classification accuracy reached up to 96.56%, higher than other linear classification models. Moreover, 200 images captured under three different illuminations in the vineyard were selected as the testing images on which the proposed approach was applied, and the average detection rate was as high as 93.74%. The experimental results show that the approach can partly restrain the influence of the complex background such as the weather condition, leaves and changing illumination.

  19. Control the wettability of poly(n-isopropylacrylamide-co-1-adamantan-1-ylmethyl acrylate) modified surfaces: the more Ada, the bigger impact?

    Science.gov (United States)

    Shi, Xiu-Juan; Chen, Gao-Jian; Wang, Yan-Wei; Yuan, Lin; Zhang, Qiang; Haddleton, David M; Chen, Hong

    2013-11-19

    Surface-initiated SET-LRP was used to synthesize polymer brush containing N-isopropylacrylamide and adamantyl acrylate using Cu(I)Cl/Me6-TREN as precursor catalyst and isopropanol/H2O as solvent. Different reaction conditions were explored to investigate the influence of different parameters (reaction time, catalyst concentration, monomer concentration) on the polymerization. Copolymers with variable 1-adamantan-1-ylmethyl acrylate (Ada) content and comparable thickness were synthesized onto silicon surfaces. Furthermore, the hydrophilic and bioactive molecule β-cyclodextrin-(mannose)7 (CDm) was synthesized and complexed with adamantane via host-guest interaction. The effect of adamantane alone and the effect of CDm together with adamantane on the wettability and thermoresponsive property of surface were investigated in detail. Experimental and molecular structure analysis showed that Ada at certain content together with CDm has the greatest impact on surface wettability. When Ada content was high (20%), copolymer-CDm surfaces showed almost no CDm complexed with Ada as the result of steric hindrance.

  20. Proceedings of the Annual National Conference on ADA Technology (9th) Held in Washington, DC on 4-7 March 1991

    Science.gov (United States)

    1991-03-07

    including user sessions, number of Imoroved usabili The CRS presents a consistent searches, number of matches, number of extractions, window and menu based...features and 7. Nielsen , K, & Shumate, K., Designing Large Real-Time syntax, is well constructed. Systems with Ada., McGraw-Hill. 4.2 Environment for

  1. Adaptation and validation of the Alzheimer's Disease Assessment Scale - Cognitive (ADAS-Cog) in a low-literacy setting in sub-Saharan Africa.

    Science.gov (United States)

    Paddick, Stella-Maria; Kisoli, Aloyce; Mkenda, Sarah; Mbowe, Godfrey; Gray, William Keith; Dotchin, Catherine; Ogunniyi, Adesola; Kisima, John; Olakehinde, Olaide; Mushi, Declare; Walker, Richard William

    2017-08-01

    This study aimed to assess the feasibility of a low-literacy adaptation of the Alzheimer's Disease Assessment Scale - Cognitive (ADAS-Cog) for use in rural sub-Saharan Africa (SSA) for interventional studies in dementia. No such adaptations currently exist. Tanzanian and Nigerian health professionals adapted the ADAS-Cog by consensus. Validation took place in a cross-sectional sample of 34 rural-dwelling older adults with mild/moderate dementia alongside 32 non-demented controls in Tanzania. Participants were oversampled for lower educational level. Inter-rater reliability was conducted by two trained raters in 22 older adults (13 with dementia) from the same population. Assessors were blind to diagnostic group. Median ADAS-Cog scores were 28.75 (interquartile range (IQR), 22.96-35.54) in mild/moderate dementia and 12.75 (IQR 9.08-16.16) in controls. The area under the receiver operating characteristic curve (AUC) was 0.973 (95% confidence interval (CI) 0.936-1.00) for dementia. Internal consistency was high (Cronbach's α 0.884) and inter-rater reliability was excellent (intra-class correlation coefficient 0.905, 95% CI 0.804-0.964). The low-literacy adaptation of the ADAS-Cog had good psychometric properties in this setting. Further evaluation in similar settings is required.

  2. Assessment of ADHD Documentation from Candidates Requesting Americans with Disabilities Act (ADA) Accommodations for the National Board of Osteopathic Medical Examiners COMLEX Exam

    Science.gov (United States)

    Joy, Javed A.; Julius, Rose J.; Akter, Rashida; Baron, David A.

    2010-01-01

    Purpose: Every year increasing numbers of candidates request special accommodations for high-stakes medical licensing examinations, due to ADHD, on the basis of the Americans with Disabilities Act (ADA). This poses significant challenges for both the applicant and the medical boards and has significant financial, legal, and ethical implications.…

  3. [The delayed word recall task using ADAS-Jcog word booklet effectively divides patients with mild cognitive impairment from normal elderly people].

    Science.gov (United States)

    Kawano, Naoko; Umegaki, Hiroyuki; Suzuki, Yusuke; Yamamoto, Sayaka; Mogi, Nanaka; Iguchi, Akihisa

    2007-07-01

    A new screening test for detecting mild cognitive impairment (MCI) with higher sensitivity that can easily be administered at the bedside is necessary. In this study, we proposed the delayed recall task using the word booklet of Alzheimer's Disease Assessment Scale-cognitive component-Japanese version (ADAS-Jcog) and compared the score of the task in patients with MCI with that of cognitive normal elderly (NE) and patients with AD. Thirty six patients with MCI, 13 very mild AD, 104 mild AD, 13 moderate AD, and age- and education-matched 19 NE, recruited from the memory clinic of Nagoya University Hospital, were evaluated by the ADAS-Jcog word recall task which consisted of immediate recall (IR), a classical method on ADAS-Jcog, and delayed recall (DR) that has been newly introduced. Compared with controls, patients with MCI were significantly impaired on both IR and DR. On the other hand, DR is more sensitive than IR for distinguishing MCI from NE. The highest sensitivity (94.4%) and specificity (68.4%) were achieved when the results of IR were combined with those of DR. The result suggests that the delayed word recall task using the word booklet of ADAS-Jcog may be a useful tool as a screening method for the detection of MCI.

  4. Okay, Our Courses Are Online, but Are They ADA Compliant? An Investigation of Faculty Awareness of Accessibility at a Midwestern University

    Science.gov (United States)

    Huss, John A.; Eastep, Shannon

    2016-01-01

    The purpose of this study was to investigate the current extent of our faculty's familiarity with the rights, responsibilities, and resources pertaining to the Americans with Disabilities Act (ADA) and Section 508 of the Workforce Rehabilitation Act insofar as compliance and accommodations for online courses. Through the collection of data we…

  5. Adding delayed recall to the ADAS-cog improves measurement precision in mild Alzheimer's disease: Implications for predicting instrumental activities of daily living.

    Science.gov (United States)

    Lowe, Deborah A; Balsis, Steve; Benge, Jared F; Doody, Rachelle S

    2015-12-01

    As research increasingly focuses on preclinical stages of Alzheimer's disease (AD), instruments must be retooled to identify early cognitive markers of AD. A supplemental delayed recall subtest for the Alzheimer's Disease Assessment Scale-cognitive (ADAS-cog; Mohs, Rosen, & Davis, 1983; Rosen, Mohs, & Davis, 1984) is commonly implemented, but it is not known precisely where along the spectrum of cognitive dysfunction this subtest yields incremental information beyond what is gained from the standard ADAS-cog, or whether it can improve prediction of functional outcomes. An item response theory approach can analyze this in a psychometrically rigorous way. Seven hundred eighty-eight patients with AD or amnestic complaints or impairment completed a battery including the ADAS-cog and 2 activities of daily living measures. The delayed recall subtest slightly improved the ADAS-cog's measurement precision in the mild range of cognitive dysfunction and increased prediction of instrumental activities of daily living for individuals with subjective memory impairment. (c) 2015 APA, all rights reserved).

  6. Graben structure in the Las Cañadas edifice (Tenerife, Canary Islands): implications for active degassing and insights on the caldera formation

    Science.gov (United States)

    Galindo, Inés; Soriano, Carles; Martí, Joan; Pérez, Nemesio

    2005-06-01

    A graben structure has been identified at the western area of the Las Cañadas caldera wall, here referred as the Los Azulejos Graben. This graben is 1 km wide and is bounded by two major normal faults trending NE-SW, the Los Azulejos Fault and the Ucanca Fault. The graben was active for at least 0.5 Ma, from the end of the Ucanca Fm to the end of the Guajara Fm, and before the collapse of the Las Cañadas edifice that formed the western caldera. A right-lateral transtension regime operated in the graben as suggested by small fault orientations and kinematics. The prolongation of the NE rift zone of Tenerife to the Cañadas edifice is the most likely volcano-tectonic scenario for the graben. In this context, inflation of phonolitic shallow magma chambers may have produced reverse faults and reactivation of normal faults. An intense and widespread hydrothermal alteration, here called Azulejos-type, occurred mainly before the graben formation, while a fault-related hydrothermal alteration occurred during and after the graben. Diffuse carbon dioxide and hydrogen degassing in and around the Las Cañadas caldera show relatively enriched values along a NE-SW trend suggesting that faults in the Los Azulejos Graben act as a pathway for deep-seated gases to the surface. Diffuse degassing and hydrothermalism indicate that the graben area has been a zone of intense fluid circulation during the evolution of the Las Cañadas edifice.

  7. Domain-specific cognitive effects of tramiprosate in patients with mild to moderate Alzheimer's disease: ADAS-cog subscale results from the Alphase Study.

    Science.gov (United States)

    Saumier, D; Duong, A; Haine, D; Garceau, D; Sampalis, J

    2009-11-01

    Tramiprosate (homotaurine, ALZHEMEDTM) was recently investigated for its efficacy, safety and disease-modification effects in a Phase III clinical study in mild to moderate Alzheimer's disease (AD) patients (the Alphase study). The primary cognitive endpoint measure of that study was the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog). To characterize potential cognitive benefits of tramiprosate, the present study describes exploratory analyses performed on scores obtained from the specific ADAS-cog subscales in order to determine whether specific domains of cognition may be differentially affected by tramiprosate, which would not have been evident from the measure's total score. Multi-center, double-blind, randomized, placebo-controlled study. 67 investigative sites in the United States and Canada. A total of 1,052 patients were randomized. Patients were randomized to receive twice a day Placebo (n=353), tramiprosate 100 mg (n=352) and tramiprosate 150 mg (n=347). ADAS-cog assessments were conducted every three months over the 78-week study period. Exploratory analyses were performed by comparing ADAS-cog subscale scores between Placebo and each active treatment arm at each visit. The findings of this analysis revealed statistically significant differences or statistical trends in favour of tramiprosate on six ADAS-cog subscales, namely Following Commands, Language Comprehension, Ideational Praxis, Object Naming, Remembering Test Instructions, and Spoken Language Ability. Differences in favor of Placebo were only observed on the Constructional Praxis subscale. This exploratory analysis suggests that tramiprosate may have some benefit on memory, language and praxis skills in mild to moderate AD individuals. Future clinical studies of tramiprosate should include specialized neuropsychological tests to validate its effects within these cognitive domains.

  8. GestAqua.AdaPT - Mediterranean river basin modeling and reservoir operation strategies for climate change adaptation

    Science.gov (United States)

    Alexandre Diogo, Paulo; Nunes, João Pedro; Marco, Machado; Aal, Carlo; Carmona Rodrigues, António; Beça, Pedro; Casanova Lino, Rafael; Rocha, João; Carvalho Santos, Cláudia

    2016-04-01

    Climate change (CC) scenarios for the Mediterranean region include an increase in the frequency and intensity of extreme weather events such as drought periods. higher average temperatures and evapotranspiration, combined with the decrease of annual precipitation may strongly affect the sustainability of water resources. In face of these risks, improving water management actions? by anticipating necessary operational measures is required to insure water quantity and quality according to the needs of the populations and irrigation in agriculture. This is clearly the case of the Alentejo region, southern Portugal, where present climatic conditions already pose significant challenges to water resources stakeholders, mainly from the agricultural and the urban supply sectors. With this in mind, the GestAqua.AdaPT project is underway during 2015 and 2016, aiming at analyzing CC impacts until 2100 and develop operational procedures to ensure water needs are adequately satisfied in the Monte Novo and Vigia reservoirs, which supply water for the city of Évora and nearby irrigation systems. Specific project objectives include: a) defining management and operational adaptation strategies aiming to ensure resource sustainability, both quantitatively and qualitatively; b) evaluate future potential costs and available alternatives to the regional water transfer infrastructure linked with the large Alqueva reservoir implemented in 2011; c) defining CC adaptation strategies to reduce irrigation water needs and d) identification of CC adaptation strategies which can be suitable also to other similar water supply systems. The methodology is centered on the implementation of a cascade of modeling tools, allowing the integrated simulation of the multiple variables under analysis. The project is based on CC scenarios resulting from the CORDEX project for 10 combinations of Global and regional climate models (GCMs and RCMs). The study follows by using two of these combinations

  9. Myndos (Asar Adası Geç Antik Dönem Seramikleri / Late Antiquity Pottery Of (Asar Island Myndos

    Directory of Open Access Journals (Sweden)

    Sinan Mimaroğlu

    2017-10-01

    ında sualtında tip olarak İS. 4. yüzyıl Yassıada batığında bulunan amphoralara benzer 10 kadar amphora bulunmuştur. 2004 ve 2006 yılları arasında Prof. Dr.Mustafa Şahin başkanlığında su altı çalışmaları ve yüzey araştırmaları gerçekleştirilmiştir. Kentteki 2008 yılında yaptırılan zemin etütleri esnasında detaylı bir şekilde incelenen Asar Adası’nda, anıtsal bir yapının varlığı tespit edilmiş ve 2009 yılında ilk bilimsel kazı çalışmalarına başlanmıştır. Tepe üzerinde yapılan çalışmalar sonucunda ortaya çıkarılan yapı katmanları, en erken Helenistik dönemden itibaren başlamaktadır. Geç Antik Dönemde tepe üzerine bazilika ve etrafına konutlar ve sarnıçlar inşa edilmiştir. En son tabakayı ise, Geç Bizans Dönemine tarihlendirilen sur duvarları temsil etmektedir. Bu makalede ilk kez ele alınan seramikler, Myndos kentinde 2009-2013 yılları arasında antik kentin limanını koruyan Asar Adası (Tavşan Adasıüzerinde sürdürülen kazı çalışmaları sırasında bulunmuşlardır. Değerlendirilen Geç Antik Döneme ait günlük seramik grupları arasında pişirme ve ısıtma kapları, kapaklar ve Kırmızı Astarlı Geç Roma Seramikleri yer almaktadır. Alanın Geç Antik Dönem yerleşimi açısından önemli veriler sunan seramikler yerleşimin dokusunu anlamamız için gerekli ipuçlarını vermektedir.

  10. ANÁLISIS DEL CONTENIDO NUTRICIONAL DE PLANTAS CONSUMIDAS POR CAPRINOS EN UNA LOCALIDAD DE LA CAÑADA, OAXACA

    Directory of Open Access Journals (Sweden)

    Anna R. Landa-Becerra

    2016-12-01

    Full Text Available Se reportan los resultados del contenido nutricional de algunas plantas consumidas por caprinos (Capra hircus en la localidad de San Gabriel Casa Blanca en la región de la Cañada dentro de la Reserva de Biosfera Tehuacán-Cuicatlán. En noviembre de 2012 (época de lluvias y en mayo de 2013 (época de seca se colectaron 16 especies de plantas consumidas frecuentemente por los caprinos. Los parámetros determinados fueron: contenido de proteína cruda, materia seca, cenizas, grasa cruda, fibra cruda, fibra detergente neutra, fibra detergente ácido, calcio, fósforo, digestibilidad in vitro de la materia seca y energía metabolizable. Los resultados se compararon por análisis multivariado. De las especies analizadas en época de lluvias Ceiba parvifolia, Waltheria indica, Prosopis leavigata, Solanum sp. y Sanvitalia procumbens aportaron mayor cantidad de proteína cruda, fibra detergente ácida, extracto libre de nitrógeno, fósforo y grasa cruda; mientras que de las colectadas en la época de secas Acacia farnesiana, Prosopis leavigata y Ziziphus pedunculata fueron fuente importante de proteína cruda, energía metabolizable y digestibilidad in vitro de la materia seca. Estos resultados pueden tener implicaciones para el manejo del alimento de los caprinos en la región de estudio.

  11. Giant gas bubbles in a rheomorphic vent fill at the Las Cañadas caldera, Tenerife (Canary Islands)

    Science.gov (United States)

    Soriano, Carles; Giordano, Daniele; Galindo, Inés; Hürlimann, Marcel; Ardia, Paola

    2009-10-01

    During rheomorphism subsequent to fallout deposition, a portion of the densely welded fallout of the La Grieta Member flowed back into the vent from where it was erupted, while the rest of it flowed down the outer slopes of the Las Cañadas caldera in Tenerife. The welded fallout and conduit-vent structure are physically connected and constitute a rare example of this type of deposits rooted to its feeder conduit and exposed in the caldera wall. The lower part of the vent-filling rheomorphic rocks shows gas bubbles and cavities that increase in size (up to 4 m) down vent. Bubbles are deformed against other bubbles, against the steep vent walls, flattened parallel to the flow foliation planes, and elongated parallel to the flow lineation and flow fold axes. The preservation of such giant bubbles, rather than their formation, seems to be a pretty unique feature of the phonolitic products investigated here and it is likely the result of the combination of factors that acted to preserve, in the surrounding of the glass transition interval, the sealing and the late stage cooling of a pressurized system. In addition, strain drop at the base of the vent-filling rheomorphic flow caused by flow stopping against vertical vent walls may have promoted rapid gas exsolution and the formation of large bubbles.

  12. Ethnobotany of medicinal plants in Ada'a District, East Shewa Zone of Oromia Regional State, Ethiopia.

    Science.gov (United States)

    Kefalew, Alemayehu; Asfaw, Zemede; Kelbessa, Ensermu

    2015-04-02

    An ethnobotanical study of medicinal plants was conducted in Ada'a District, Eastern Shewa Zone of Oromia Regional State of Ethiopia. The objective of the study was to identify and document medicinal plants and the associated ethnobotanical/ethnomedicinal knowledge of the local people. Relevant ethnobotanical data focused on medicinal plants and traditional herbal medicines were collected using guided field walk, semi-structured interview and direct field observation. Informant consensus method and group discussion were conducted for crosschecking and verification of the information. Both descriptive statistics and quantitative ethnobotanical methods were used for data analysis. We documented 131 species distributed in 109 genera and 54 families based on local claims of medicinal values. Patients who are using traditional drugs and herbalists collect most of these plants from the wild. The leading plant families that encompass large medicinal species were the Lamiaceae (14 species) followed by Asteraceae (13) and Solanaceae (7). The study reported the existence of a number of medicinal plants, an indication for the presence of plant-based traditional medicinal knowledge transfer that survived through generations. Informants asserted that wild growing medicinal plants are under threat due to increased use pressure coupled with unsuitable harvesting that frequently targets roots and barks for remedy preparations. This calls for urgent and collaborative actions to keep the balance between medicinal plants availability in the wild state and their utilization by the community. Furthermore, the study attempted to prioritize the most efficacious medicinal plants as perceived by the local people for possible pharmacological testing.

  13. Early breast cancer detection with digital mammograms using Haar-like features and AdaBoost algorithm

    Science.gov (United States)

    Zheng, Yufeng; Yang, Clifford; Merkulov, Alex; Bandari, Malavika

    2016-05-01

    The current computer-aided detection (CAD) methods are not sufficiently accurate in detecting masses, especially in dense breasts and/or small masses (typically at their early stages). A small mass may not be perceived when it is small and/or homogeneous with surrounding tissues. Possible reasons for the limited performance of existing CAD methods are lack of multiscale analysis and unification of variant masses. The speed of CAD analysis is important for field applications. We propose a new CAD model for mass detection, which extracts simple Haar-like features for fast detection, uses AdaBoost approach for feature selection and classifier training, applies cascading classifiers for reduction of false positives, and utilizes multiscale detection for variant sizes of masses. In addition to Haar features, local binary pattern (LBP) and histograms of oriented gradient (HOG) are extracted and applied to mass detection. The performance of a CAD system can be measured with true positive rate (TPR) and false positives per image (FPI). We are collecting our own digital mammograms for the proposed research. The proposed CAD model will be initially demonstrated with mass detection including architecture distortion.

  14. A non-sense mutation in the putative anti-mutator gene ada/alkA of Mycobacterium tuberculosis and M. bovis isolates suggests convergent evolution

    Directory of Open Access Journals (Sweden)

    Gicquel Brigitte

    2007-05-01

    Full Text Available Abstract Background Previous studies have suggested that variations in DNA repair genes of W-Beijing strains may have led to transient mutator phenotypes which in turn may have contributed to host adaptation of this strain family. Single nucleotide polymorphism (SNP in the DNA repair gene mutT1 was identified in MDR-prone strains from the Central African Republic. A Mycobacteriumtuberculosis H37Rv mutant inactivated in two DNA repair genes, namely ada/alkA and ogt, was shown to display a hypermutator phenotype. We then looked for polymorphisms in these genes in Central African Republic strains (CAR. Results In this study, 55 MDR and 194 non-MDR strains were analyzed. Variations in DNA repair genes ada/alkA and ogt were identified. Among them, by comparison to M. tuberculosis published sequences, we found a non-sense variation in ada/alkA gene which was also observed in M. bovis AF2122 strain. SNPs that are present in the adjacent regions to the amber variation are different in M. bovis and in M. tuberculosis strain. Conclusion An Amber codon was found in the ada/alkA locus of clustered M. tuberculosis isolates and in M. bovis strain AF2122. This is likely due to convergent evolution because SNP differences between strains are incompatible with horizontal transfer of an entire gene. This suggests that such a variation may confer a selective advantage and be implicated in hypermutator phenotype expression, which in turn contributes to adaptation to environmental changes.

  15. A Clinical Practice Update on the Latest AAOS/ADA Guideline (December 2012) on Prevention of Orthopaedic Implant Infection in Dental Patients

    OpenAIRE

    Hamedani, Sh

    2013-01-01

    The American Academy of Orthopaedic Surgeons (AAOS) and the American Dental Association (ADA), along with 10 other academic associations and societies recently (December 2012) published their mutual clinical practice guideline “Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures.” This evidence-based guideline ,detailed in 325 pages, has three recommendations and substitutes the previous AAOS guideline. The new published clinical guideline is a protocol to pre...

  16. Zeitabhängige Putzeffektivität einer Schallzahnbürste im Vergleich mit einer ADA-Referenz-Handzahnbürste

    OpenAIRE

    Pelka, Anna-Kristina

    2010-01-01

    Ziel der Studie war, in einer Kurzzeituntersuchung das Putzergebnis zweier unterschiedlicher Zahnbürsten zeitabhängig zu evaluieren. Zum Einsatz kamen die Sonicare elite 9800 Langkopf und eine ADA – Handzahnbürste. The purpose of the present study was to evaluate the plaque-removal efficacy of different toothbrushes for smooth and approximal surfaces in relation to brushing time. The brushes which were studied were the power toothbrush Sonicare e9800 (Philips) with the long brushing head a...

  17. Proceedings of the National Conference on Ada (trade mark) Technology (6th) Held on 14-18 March 1988 in Arlington, VA.

    Science.gov (United States)

    1988-03-01

    Advanced Ada Tasking Techniques for Motor Simula- Queueing Networks Modeling and Simulation-O. tion and Control-i LT L. S. Kim, Ft. Belvoir, VA ....... 269...sends the BC its PROCESO C status word where it is checked to determine the success of the information transfer. 4.2 Simulation Environment eI The...the communications sycste oes nal-ot eacnt f or interface system is unusable with dynamically proceso fauit-erace (foesor cassti declared data that

  18. Influências de fibra de aço no comportamento estrutural de vigotas reforçadas com PRFC

    Directory of Open Access Journals (Sweden)

    V. J. Ferrari

    Full Text Available Neste trabalho, apresenta-se a metodologia utilizada e os resultados da análise do comportamento de vigotas armadas e reforçadas externamente à flexão com manta de PRFC (polímeros reforçados com fibras de carbono. Avalia-se o comportamento do reforço de vigotas de concreto comum e compara-o com o do reforço de vigotas moldadas com um compósito cimentício à base de argamassa e fibras curtas de aço. O objetivo principal foi investigar a influência do compósito cimentício (escolhido sem maiores critérios sobre o comportamento e o modo de ruína das vigotas reforçadas. Para tanto, uma série de ensaios de flexão em três pontos em seis vigotas foi conduzida, além dos ensaios de caracterização dos materiais: ensaios de flexão em três pontos em corpos-de-prova prismáticos entalhados, ensaios de tração em barras de aço e ensaios de compressão axial em corpos-de-prova cilíndricos. Adicionalmente, uma análise de elementos finitos foi desenvolvida com objetivo de comparar os resultados obtidos com os experimentais. O ganho de tenacidade e de resistência à fissuração provocou mudanças significativas no desempenho da vigota moldada com fibras e reforçada quando comparada com a vigota reforçada de concreto comum.

  19. Contribution of the geophysical and radon techniques to characterize hydrogeological setting in the western volcanic zone of Yarmouk basin: Case study Deir El-Adas

    International Nuclear Information System (INIS)

    Al-Fares, W.; Soliman, E.; Al-Ali, A.

    2009-01-01

    The aim of this study is to illustrate the geophysical and radon techniques in characterizing ''at local scale'' a hydrogeological setting in the volcanic zone of Yarmouk basin. And to employ the obtained results to understand and explain similar hydrogeological situation related to particular subsurface geologic and tectonic structure. Based on the field observations and failed wells drilled at Deir El-Adas, and the occurrence of successful well out of that zone, all these reasons, have given us the incentive to verify and provide realistic explanation of this phenomena in the basaltic outcrops of Yarmouk basin. The interpretation of the vertical electrical surveys (VES), indicates to the presence of local faulted anticline structure of Palaeogene located under the volcanic outcrops. This structure has led to complex hydrogeological conditions, represented by limited recharge in this area which occurs through fractures and secondary faults in addition to the low direct precipitation. Piezometric map indicates to water divide in the north-west of Deir El-Adas related to the tectonic setting. Meanwhile, discharge map show low reproducibility of drilled wells in Deir El-Adas and its periphery. Due to limited radon data, it was difficult to draw concrete conclusions from this technique. (author)

  20. An evaluation of seepage gains and losses in Indian Creek Reservoir, Ada County, Idaho, April 2010–November 2011

    Science.gov (United States)

    Williams, Marshall L.; Etheridge, Alexandra B.

    2013-01-01

    The U.S. Geological Survey, in cooperation with the Idaho Department of Water Resources, conducted an investigation on Indian Creek Reservoir, a small impoundment in east Ada County, Idaho, to quantify groundwater seepage into and out of the reservoir. Data from the study will assist the Idaho Water Resources Department’s Comprehensive Aquifer Management Planning effort to estimate available water resources in Ada County. Three independent methods were utilized to estimate groundwater seepage: (1) the water-budget method; (2) the seepage-meter method; and (3) the segmented Darcy method. Reservoir seepage was quantified during the periods of April through August 2010 and February through November 2011. With the water-budget method, all measureable sources of inflow to and outflow from the reservoir were quantified, with the exception of groundwater; the water-budget equation was solved for groundwater inflow to or outflow from the reservoir. The seepage-meter method relies on the placement of seepage meters into the bottom sediments of the reservoir for the direct measurement of water flux across the sediment-water interface. The segmented-Darcy method utilizes a combination of water-level measurements in the reservoir and in adjacent near-shore wells to calculate water-table gradients between the wells and the reservoir within defined segments of the reservoir shoreline. The Darcy equation was used to calculate groundwater inflow to and outflow from the reservoir. Water-budget results provided continuous, daily estimates of seepage over the full period of data collection, while the seepage-meter and segmented Darcy methods provided instantaneous estimates of seepage. As a result of these and other difference in methodologies, comparisons of seepage estimates provided by the three methods are considered semi-quantitative. The results of the water-budget derived estimates of seepage indicate seepage to be seasonally variable in terms of the direction and magnitude

  1. Diffuse CO2 flux emissions from the soil in Las Cañadas caldera (Tenerife, Canary Islands)

    Science.gov (United States)

    Luengo-Oroz, Natividad; Torres, Pedro A.; Moure, David; D'Alessandro, Walter; Liuzzo, Marco; Longo, Manfredi; Pecoraino, Giovannella

    2014-05-01

    Starting in April 2004, unusual seismic activity was observed in the interior of the island of Tenerife (Canary Islands, Spain) with much evidence pointing to a reawakening of volcanic activity. During this seismic crisis, several events were felt by the population. Since then, a dense multiparametric monitoring network has been deployed all over the island by Instituto Geográfico Nacional (IGN). In the framework of this volcanic surveillance project, several geochemical studies have been accomplished. Measurements of diffuse CO2 flux from the soil have been carried out in some zones inside Las Cañadas caldera. This study has been performed during three different field campaigns in November 2012 and June and November 2013. The studied area includes two different zones known as Roques de García and Los Azulejos. Since several authors have reported the existence of fractures and faults all along both structures, the objectives of this work were to find anomalous CO2 fluxes from the soil and preferential degassing areas, identify possible hidden faults and study the origin of gas emanations in order to detect the presence of magmatic sources. More than 600 sampling sites have been measured with the accumulation chamber method in an area of about 1 km2. Soil gas has been sampled in points where high CO2 fluxes were detected for the determination of chemical and isotopic composition. The results of the gas prospection confirm the existence of CO2 degassing in the area. Some anomalous fluxes have been measured along previously inferred volcano-tectonic structures. The highest anomalies were found in Los Azulejos with values up to 1774 g/m2.d. Chemical analysis did not reveal significant concentrations of magmatic or geothermal gases except CO2. The latter showed concentrations at 50 cm depth within the soils up to 48% and a C-isotopic composition between -4.72 and -3.67 o indicating a prevailing magmatic origin.

  2. Utilização de plaquetas e de produtos derivados de plaquetas humanas em terapias avançadas

    Directory of Open Access Journals (Sweden)

    Marcus Vinicius Telles Teixeira

    2018-02-01

    Full Text Available Introdução: As plaquetas têm um papel central no processo da resposta tecidual à injúria, atuando na hemostasia primária e na coagulação, e liberando de maneira coordenada as moléculas bioativas importantes para a angiogênese e para a regeneração tecidual. O uso clínico não transfusional de produtos derivados de plaquetas, como o Plasma Rico em Plaquetas (PRP, baseia-se na sua habilidade de maximizar o processo de regeneração celular, em lesões com dificuldades de reparo natural. Objetivo: Esta revisão aborda as características e potencialidades do uso clínico de plaquetas e seus derivados e discute seu arcabouço legislativo no contexto brasileiro. Método: Foram consultadas as bases de dados PubMed, Biblioteca Virtual em Saúde, páginas eletrônicas da Anvisa e do ministério da Saúde, entre setembro 2017 e janeiro de 2018. Resultado: O PRP é produto derivado de plaquetas que não pode ser quimicamente definido, e o seu uso clínico aqui discutido não é ortólogo. Conclusão: Dessa maneira, podemos considerar a aplicação do PRP como uma Terapia Celular Avançada, sendo fundamental padronizar protocolos, estabelecer critérios de controle de qualidade (rastreabilidade, eficácia e fármaco-vigilância, tornando seu uso devidamente controlado pelos órgãos competentes, com maior segurança na sua utilização.

  3. ADaCGH: A parallelized web-based application and R package for the analysis of aCGH data.

    Directory of Open Access Journals (Sweden)

    Ramón Díaz-Uriarte

    Full Text Available BACKGROUND: Copy number alterations (CNAs in genomic DNA have been associated with complex human diseases, including cancer. One of the most common techniques to detect CNAs is array-based comparative genomic hybridization (aCGH. The availability of aCGH platforms and the need for identification of CNAs has resulted in a wealth of methodological studies. METHODOLOGY/PRINCIPAL FINDINGS: ADaCGH is an R package and a web-based application for the analysis of aCGH data. It implements eight methods for detection of CNAs, gains and losses of genomic DNA, including all of the best performing ones from two recent reviews (CBS, GLAD, CGHseg, HMM. For improved speed, we use parallel computing (via MPI. Additional information (GO terms, PubMed citations, KEGG and Reactome pathways is available for individual genes, and for sets of genes with altered copy numbers. CONCLUSIONS/SIGNIFICANCE: ADACGH represents a qualitative increase in the standards of these types of applications: a all of the best performing algorithms are included, not just one or two; b we do not limit ourselves to providing a thin layer of CGI on top of existing BioConductor packages, but instead carefully use parallelization, examining different schemes, and are able to achieve significant decreases in user waiting time (factors up to 45x; c we have added functionality not currently available in some methods, to adapt to recent recommendations (e.g., merging of segmentation results in wavelet-based and CGHseg algorithms; d we incorporate redundancy, fault-tolerance and checkpointing, which are unique among web-based, parallelized applications; e all of the code is available under open source licenses, allowing to build upon, copy, and adapt our code for other software projects.

  4. Spt-Ada-Gcn5-Acetyltransferase (SAGA Complex in Plants: Genome Wide Identification, Evolutionary Conservation and Functional Determination.

    Directory of Open Access Journals (Sweden)

    Rakesh Srivastava

    Full Text Available The recruitment of RNA polymerase II on a promoter is assisted by the assembly of basal transcriptional machinery in eukaryotes. The Spt-Ada-Gcn5-Acetyltransferase (SAGA complex plays an important role in transcription regulation in eukaryotes. However, even in the advent of genome sequencing of various plants, SAGA complex has been poorly defined for their components and roles in plant development and physiological functions. Computational analysis of Arabidopsis thaliana and Oryza sativa genomes for SAGA complex resulted in the identification of 17 to 18 potential candidates for SAGA subunits. We have further classified the SAGA complex based on the conserved domains. Phylogenetic analysis revealed that the SAGA complex proteins are evolutionary conserved between plants, yeast and mammals. Functional annotation showed that they participate not only in chromatin remodeling and gene regulation, but also in different biological processes, which could be indirect and possibly mediated via the regulation of gene expression. The in silico expression analysis of the SAGA components in Arabidopsis and O. sativa clearly indicates that its components have a distinct expression profile at different developmental stages. The co-expression analysis of the SAGA components suggests that many of these subunits co-express at different developmental stages, during hormonal interaction and in response to stress conditions. Quantitative real-time PCR analysis of SAGA component genes further confirmed their expression in different plant tissues and stresses. The expression of representative salt, heat and light inducible genes were affected in mutant lines of SAGA subunits in Arabidopsis. Altogether, the present study reveals expedient evidences of involvement of the SAGA complex in plant gene regulation and stress responses.

  5. Comparative Efficacy of a Soft Toothbrush with Tapered-tip Bristles and an ADA Reference Toothbrush on Established Gingivitis and Supragingival Plaque over a 12-Week Period.

    Science.gov (United States)

    Gallob, John; Petrone, Dolores M; Mateo, Luis R; Chaknis, Patricia; Morrison, Boyce M; Williams, Malcolm; Panagakos, Foti

    2016-06-01

    Evaluation of the efficacy of a soft toothbrush with tapered-tip bristles (Test Toothbrush) and an ADA reference soft toothbrush (ADA Toothbrush) on established gingivitis and supragingival plaque over a 12-week period. This randomized, single-center, examiner-blind, two-cell, parallel clinical research study assessed plaque removal by the comparison of pre- to- post-brushing after a single use, and again after six- and 12-weeks' use, using the Quigley-Hein Plaque Index, Turesky Modification. The study also assessed gingivitis after six weeks and 12 weeks using the Löe & Silness Gingival Index. Adult male and female subjects from the Central New Jersey, USA area refrained from all oral hygiene procedures for 24 hours. They reported to the study site after refraining from eating, drinking, and smoking for four hours. Subjects had the study procedure explained to them both orally and by written instructions. Subjects then gave written consent to participate before entry into the study. Following an examination for plaque (pre-brushing) and gingivitis (baseline), the subjects were randomized into two balanced groups, each group assigned to one of the two study toothbrushes. Subjects were instructed to brush their teeth for one minute under supervision with their assigned toothbrush and a commercially available fluoride toothpaste (Colgate© Cavity Protection Toothpaste), after which they were again evaluated for plaque (post-brushing). Subjects were dismissed from the study site with their assigned toothbrush and toothpaste, and instructed to brush twice daily at home for the next 12 weeks. The subjects were instructed to brush for one minute during each tooth brushing. The subjects reported to the study site after six weeks and 12 weeks of product use, at which time they were evaluated for plaque and gingivitis. Seventy-one (71) subjects complied with the protocol and completed the clinical study. Compared to the ADA Toothbrush, the Test Toothbrush provided

  6. The validity and reliability of the Turkish version of Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) in patients with mild and moderate Alzheimer's disease and normal subjects.

    Science.gov (United States)

    Mavioglu, H; Gedizlioglu, M; Akyel, S; Aslaner, T; Eser, E

    2006-03-01

    The cognitive subscale of the Alzheimer's Disease Assesment Scale (ADAS-Cog) is the most widely used test in clinical trials dealing with Alzheimer's disease (AD). The aim of this study was to investigate the validity and reliability of the Turkish version of ADAS-Cog. Twenty-nine patients with AD, fulfilling NINCDS-ADRDA criteria of probable AD, who were in stage 3-5 according to the Global Deterioration Scale (GDS), and 27 non-demented control subjects with similar age, gender and educational status were recruited for the study. The Turkish version of ADAS-Cog, Standardized Mini Mental Status Examination (MMSE) and Short Orientation-Memory-Concentration Test (SOMCT) were applied to both of the groups. Inter-rater reliability, internal consistency, test-retest reliability; face validity, differential validity and convergent validity were statistically analyzed. Both MMSE and ADAS-Cog have significantly differentiated patients with AD and control subjects (p ADAS-Cog scores in AD group (r: -0.739). ADAS-Cog was also highly significantly correlated with GDS (r: 0.720) and SOMCT (r: 0.738). For the group with AD, control and whole cohort coefficients of internal consistency, Cronbach's alpha: 0.800, 0.515, 0.873 were found respectively. Inter-rater reliability for total ADAS-Cog score was found as ICC: 0.99 and 0.98 and test-retest reliability was found as ICC: 0.91 and 0.95 for demented and nondemented subjects, respectively. The Turkish version of ADAS-Cog has been found to be highly reliable and valid in differentiating patients with mild and moderate AD from nondemented subjects.

  7. ADA Test and Evaluation

    Science.gov (United States)

    1981-02-06

    NRL) hID THEN and 0 iL3t R93- 01 pgs. I. grutat (NRL) Comment Convention 193- 02 pgs. R. Krutar (I’L) EXIT Statement 195- 103 Pgn. Marc RubbArd (WC...vs. *Parts* 079- 00 ps. C. H. Lindsey Meologisms; Various Points 080- 00 ps. V. R. LaLonde Strings 081- 00 ps. (ZABO) Systems Programming: Various...of Oser-Derined Type 096- 00 pgs. (Germany) Else Syntax Error-Prone 097- 00 pg.. V. R. LaLonde String. 098- 00 Pg.. Thomas A. Marainial Permanent

  8. ADA Tasking Performance Issues

    Science.gov (United States)

    1990-02-09

    alternativa 194 not available wait for alternative to be selected 489 150 Completion of Rendezvous 820 not available Exception within accept body 159 not...the latency predictable. Essentially none of the popular networks provide support for mair a, ing accurate time, access to global memory, or good

  9. Advanced Ada (Trademark).

    Science.gov (United States)

    1984-07-01

    Hedge"), new String’("Seasonal Shrub"), new F’ring’("Jolly Gymnosperm "), new String’("Ceremonial Cedar"), new String’ ("Inebriate Evergreen")); So, we...8217("Christmas Tree"), new String’("Holiday Hedge"), new String’ ("Seasonal Shrub"), new String’("Jolly Gymnosperm "), new Strina’("Ceremonial Cedar

  10. Proposta de marco regulatório para os Produtos de Terapias Avançadas no Brasil

    Directory of Open Access Journals (Sweden)

    Renata Miranda Parca

    2018-02-01

    Full Text Available Introdução: Os Produtos de Terapias Avançadas (PTA têm sido a grande promessa terapêutica para o tratamento de diversas doenças, inclusive aquelas para as quais não existe alternativa disponível no mercado. Estes produtos, obtidos a partir de células humanas,foram categorizados em âmbito internacional como nova classe terapêutica para a qual a regulamentação adotada assemelha-se à dos medicamentos biológicos, embora com abordagem e critérios diferenciados devido às peculiaridades dos PTA. Objetivo: O presente artigo tem como objetivos descrever o histórico das discussões e regulamentações editadas para a temática e apresentar as perspectivas relacionadas ao desenvolvimento do marco regulatório brasileiro para esta nova categoria de produto, a fim de propiciar um ambiente regulatório estável e transparente, favorável ao desenvolvimento tecnológico em âmbito nacional, bem como ao fomento através de investimentos nacionais e internacionais. Método: O desenvolvimento deste artigo baseou-se na pesquisa do histórico de normativos sobre o tema, nas iniciativas regulatórias adotadas pela Anvisa, bem como na experiência dos autores a partir de participação em fóruns e discussões afetas à área. Resultados: Fundamentação do marco regulatório sanitário nacional para PTA a ser elaborado, e exposição dos principais aspectos da proposta. Conclusões: A proposta de marco regulatório nacional para os PTAs abarcará regulamentos para avaliação e aprovação de ensaios clínicos pela Anvisa, Certificação de Boas Práticas em Células para estabelecimentos produtores e registro de produtos.

  11. Genetic Polymorphisms are Associated with Hair, Blood, and Urine Mercury Levels in the American Dental Association (ADA) Study Participants

    Science.gov (United States)

    Parajuli, Rajendra Prasad; Goodrich, Jaclyn M.; Chou, Hwai-Nan; Gruninger, Stephen E.; Dolinoy, Dana C.; Franzblau, Alfred; Basu, Niladri

    2015-01-01

    Background/Aims Mercury (Hg) is a potent toxicant of concern to the general public. Recent studies suggest that several genes that mediate Hg metabolism are polymorphic. We hypothesize that single nucleotide polymorphisms (SNPs) in such genes may underline inter-individual differences in exposure biomarker concentrations. Methods Dental professionals were recruited during the American Dental Association (ADA) 2012 Annual Meeting. Samples of hair, blood, and urine were collected for quantifying Hg levels and genotyping (88 SNPs in classes relevant to Hg toxicokinetics including glutathione metabolism, selenoproteins, metallothioneins, and xenobiotic transporters). Questionnaires were administrated to obtain information on demographics and sources of Hg exposure (e.g., fish consumption and use of dental amalgam). Here, we report results for 380 participants with complete genotype and Hg biomarker datasets. ANOVA and linear regressions were used for statistical analysis. Results Mean (geometric) Hg levels in hair (hHg), blood (bHg), urine (uHg), and the average estimated Hg intake from fish were 0.62μg/g, 3.75μg/L, 1.32μg/L, and 0.12μg/kg body weight/day, respectively. Out of 88 SNPs successfully genotyped, Hg biomarker levels differed by genotype for 25 SNPs, one of which remained significant following Bonferroni correction in ANOVA. When the associations between sources of Hg exposure and SNPs were analyzed with respect to Hg biomarker concentrations, 38 SNPs had significant main effects and/or gene-Hg exposure source interactions. Twenty-five, 23, and four SNPs showed significant main effects and/or interactions for hHg, bHg, and uHg levels, respectively (p<0.05), and six SNPs (in GCLC, MT1M, MT4, ATP7B, and BDNF) remained significant following Bonferroni correction. Conclusion The findings suggest that polymorphisms in environmentally-responsive genes can influence Hg biomarker levels. Hence, consideration of such gene-environment factors may improve the

  12. Comparative Efficacy of a Soft Toothbrush with Tapered-tip Bristles to an ADA Reference Toothbrush on Gingival Abrasion over a 12-Week Period.

    Science.gov (United States)

    Gallob, John; Petrone, Dolores M; Mateo, Luis R; Chaknis, Patricia; Morrison, Boyce M; Panagakos, Foti; Williams, Malcolm

    2016-06-01

    Evaluation of the impact of a soft toothbrush with tapered-tip (Test Toothbrush) bristles and an ADA reference toothbrush (ADA Toothbrush) on gingival abrasion over a 12-week period. This was a randomized, single-center, examiner-blind, two-cell, parallel clinical research study and used the Danser Gingival Abrasion Index to assess the level of gingival abrasion after a single brushing, as well as after six weeks and 12 weeks of twice-daily brushing. Adult male and female subjects from the Central New Jersey, USA area refrained from all oral hygiene procedures for 24 hours. They reported to the study site after refraining from eating, drinking, and smoking for four hours. Following a qualifying examination using plaque and gingivitis scores along with a baseline gingival abrasion examination, subjects were randomized into two balanced groups, each group using one of the two study toothbrushes. Subjects were instructed to brush their teeth for one minute, under supervision, with their assigned toothbrush and a commercially available fluoride toothpaste (Colgate© Cavity Protection Toothpaste), after which they were again evaluated for gingival abrasion. Subjects were dismissed from the study site with their assigned toothbrush and toothpaste, and instructed to brush twice daily at home for the next 12 weeks. The subjects were instructed to brush for one minute during each tooth brushing. The subjects reported to the study site after six weeks and 12 weeks of product use, at which time they were evaluated for gingival abrasion. Seventy-one (71) subjects complied with the protocol and completed the clinical study. The results of this study showed that the Test Toothbrush provided statistically significantly (p Toothbrush after a single tooth brushing, after six weeks, and after 12 weeks of product use (75.0%, 85.5%, 73.9%, respectively). The soft toothbrush with tapered-tip bristles produced significantly less gingival abrasion after 12 weeks of product use as

  13. Riesgo suicida según la tríada cognitiva negativa, ideación, desesperanza y depresión

    Directory of Open Access Journals (Sweden)

    Ronald Alberto Toro-Tobar

    2016-01-01

    Full Text Available Objetivo: establecer la relación entre ideación suicida, desesperanza, tríada cognitiva negativa y depresión, como evidencia del mo- delo cognitivo del riesgo suicida. Método: estudio empírico-analítico con diseño descriptivo, correlacional y comparativo. Las variables fueron medidas con los inventarios BDI-II, PANSI e ITC y la escala BHS. La muestra final estuvo constituida por 90 personas de ambos sexos, con una media de edad de 24,2 años (DT = 8,65 años pertenecientes a diversos niveles socioeconómicos, con estudios universi- tarios, principalmente. Resultados: se encontraron correlaciones estadísticamente significativas entre ideación suicida, desesperanza, depresión y la tríada cognitiva negativa. Las diferencias fueron significativas entre los grupos depresivos y no depresivos, con grandes efectos para las tres variables cognitivas. Interpretación y conclusiones: estos resultados constituyen nueva evidencia del modelo cognitivo planteado acerca de la relación entre las variables depresión, tríada cognitiva negativa, ideación suicida y desesperanza, tal como se ha propuesto en distintas revisiones sobre cognición negativa y suicidio. Se analizaron las limitaciones del estudio en cuanto el reducido tamaño muestral y las diferencias entre sexos para depresión ante estresores específicos, y las variaciones por grupos de edades en el riesgo suicida de los jóvenes.

  14. An AdaBoost Based Approach to Automatic Classification and Detection of Buildings Footprints, Vegetation Areas and Roads from Satellite Images

    Science.gov (United States)

    Gonulalan, Cansu

    In recent years, there has been an increasing demand for applications to monitor the targets related to land-use, using remote sensing images. Advances in remote sensing satellites give rise to the research in this area. Many applications ranging from urban growth planning to homeland security have already used the algorithms for automated object recognition from remote sensing imagery. However, they have still problems such as low accuracy on detection of targets, specific algorithms for a specific area etc. In this thesis, we focus on an automatic approach to classify and detect building foot-prints, road networks and vegetation areas. The automatic interpretation of visual data is a comprehensive task in computer vision field. The machine learning approaches improve the capability of classification in an intelligent way. We propose a method, which has high accuracy on detection and classification. The multi class classification is developed for detecting multiple objects. We present an AdaBoost-based approach along with the supervised learning algorithm. The combi- nation of AdaBoost with "Attentional Cascade" is adopted from Viola and Jones [1]. This combination decreases the computation time and gives opportunity to real time applications. For the feature extraction step, our contribution is to combine Haar-like features that include corner, rectangle and Gabor. Among all features, AdaBoost selects only critical features and generates in extremely efficient cascade structured classifier. Finally, we present and evaluate our experimental results. The overall system is tested and high performance of detection is achieved. The precision rate of the final multi-class classifier is over 98%.

  15. Produção e qualidade dos ovos de poedeiras comerciais submetidas a programas de muda forçada

    OpenAIRE

    Dalanezi, José Antonio [UNESP

    2007-01-01

    O objetivo deste trabalho foi de avaliar os efeitos do jejum, milho, farelo de trigo e ração de muda no processo de muda forçada em poedeiras comerciais com 73 semanas de idade. O trabalho foi conduzido na UNESP - FMVZ - no setor de avicultura, Câmpus de Botucatu. As aves foram alojadas em gaiolas com dois compartimentos internos, com quatro aves por compartimento, totalizando oito aves por gaiola. Foram utilizadas 512 poedeiras comerciais da linhagem Shaver. Durante o período de muda, as ave...

  16. O gesto em dança: descrição da gestualidade em uma narrativa dançada

    OpenAIRE

    Ana Luisa Seelaender

    2013-01-01

    Este trabalho tem como objetivo descrever e analisar os gestos produzidos em contexto de narrativa dançada, tomando como base os estudos dos gestos que acompanham a fala (Kendon 2004, McNeill 1992, Kita et al. 1998, Mittelberg 2006, Streeck 2009, entre outros). Para esse fim, adapto para o discurso dançado a proposta de estrutura tripartite de Poyatos (2002) para o discurso oral. Poyatos prevê os níveis linguístico (elementos segmentáveis), paralinguístico (elementos supressegmentais), e quin...

  17. O Impacto da Idade Materna Avançada sobre os Resultados da Gravidez Impact of Advanced Maternal Age on the Outcome of Pregnancy

    Directory of Open Access Journals (Sweden)

    José G. Cecatti

    1998-08-01

    Full Text Available Objetivo: identificar o efeito da idade sobre os resultados maternos e perinatais das gestações ocorridas em mulheres com 40 anos ou mais. Métodos: comparamos 494 gestantes com mais de 40 anos, com 988 gestantes com idade entre 20 e 29 anos, pareando-as por paridade. Após controlar possíveis variáveis confundidoras pela análise multivariada, a idade materna avançada manteve associação com a maior prevalência de hipertensão arterial, apresentação anômala, parto por cesária, hemorragia puerperal, índice de Apgar baixo, morte perinatal, natimortalidade e sofrimento fetal intraparto. Resultados: a idade materna avançada esteve isoladamente associada à hipertensão arterial, apresentação anômala, diagnóstico de sofrimento fetal intraparto, parto por cesária e hemorragia puerperal. Com relação aos resultados neonatais, a idade materna avançada estava associada independentemente apenas ao baixo índice de Apgar, morte perinatal e óbito fetal. Conclusões: esses achados mostram a necessidade de assistência obstétrica adequada com atenção especial a esses fatores para procurar melhorar os resultados maternos e perinatais das gestantes com idade avançada.Most authors agree on the negative impact of pregnancy in women with advanced maternal age on maternal and perinatal outcome. However, it is not usual to evaluate if some considered risk factors are only confounders because they are present in women over forty years. In order to identify the isolated effect of age on maternal and perinatal outcome of pregnancies in women over forty, 494 pregnancies from this age group were compared to 988 pregnancies among women aged 20 to 29 years, matched by parity. After controlling possible confounding variables through multivariate analysis, advanced maternal age maintained its association with a higher prevalence of hypertension, malpresentation, cesarean section, postpartum hemorrhage, low Apgar score, perinatal death, late fetal

  18. Influência da cultivar nas características sensoriais de azeitonas verdes descaroçadas produzidas em Trás-os-Montes.

    OpenAIRE

    Sousa, A.; Malheiro, Ricardo; Rodrigues, S.; Casal, Susana; Bento, Albino; Pereira, J.A.

    2009-01-01

    As azeitonas verdes descaroçadas, regionalmente apelidadas de "alcaparras", são um tipo de azeitona de mesa produzido de forma tradicional e muito apreciadas em Trás-os-Montes. Inicialmente, a produção deste tipo de azeitonas era vista como um aproveitamento de frutos caídos da oliveira, sobretudo a partir de meados e finais de Setembro, situação alterada hoje em dia devido ao preço que este produto atinge. Na Elaboração deste tipo de azeitonas, os frutos são colhidos verdes, part...

  19. Desarrollo de una herramienta de diagnóstico de fallos en motores de inducción mediante la técnica AdaBoost

    OpenAIRE

    Obregón Sandoval, Juan

    2016-01-01

    El objetivo de este Trabajo Fin de Máster es el de valorar la utilidad de los métodos de aprendizaje automático conocidos como AdaBoost para realizar una clasificación de motores de inducción en función del estado de las barras del rotor. De esta forma, se trata de ser capaces de identificar la avería de barra rota a partir de distintos predictores obtenidos del análisis de la corriente de alimentación del motor. Para conseguir tal fin se utilizará el software comercial MATLAB, desarrollan...

  20. Usos e Potencialidades da Cachoeira do Córrego da Caçada (Ituiutaba, MG Para o Lazer e o Turismo de Natureza

    Directory of Open Access Journals (Sweden)

    Anderson Pereira Portuguez

    2012-12-01

    Full Text Available Este trabalho buscou analisar os usos e potencialidades de lazer e do turismo de natureza na Cachoeira do Córrego da Caçada em Ituiutaba - MG. Para tanto, observou-se o potencial turístico da queda d’água a partir dos seguintes critérios: distância da queda até o centro da cidade; facilidade de acesso; tipo de propriedade; riqueza da cobertura vegetal do entorno; altura da queda; qualidade visual da água; atividades esportivas possíveis e outras. A Cachoeira do Córrego da Caçada apresenta potencial para o turismo de natureza, porém o que se pode dizer que ocorre hoje no local é lazer em ambiente natural. A visitação à queda d'água poderia enriquecer o “Circuito Turístico Águas do Cerrado”, pois conta com viabilidades ecoturística, geoturística e de turismo rural. Contudo, para que o local passe a fazer parte de um circuito turístico faz-se necessário o aprimoramento da infra-estrutura local e a capacitação dos envolvidos na recepção dos visitantes.

  1. AKTIVITAS ANTIBAKTERI EKSTRAK BUAH ADAS (Foeniculum vulgare, Mill PADA Vibrio harveyi DAN Vibrio alginolyticus Antibacterial Activity of Fennel (Foeniculum vulgare Mill Extract on Vibrio alginolyticus and Vibrio harveyi

    Directory of Open Access Journals (Sweden)

    Budianto Budianto

    2015-10-01

    Pada penelitian ini menggunakan ekstrak air dari buah adas untuk mengetahui aktivitas antibakteri terhadap Vibrio harveyi dan Vibrio alginolyticus dengan menggunakan metode uji Minimum Inhibitory Concentration (MIC dan difusi cakram kertas. Hasil yang diperoleh pada uji MIC, konsentrasi terkecil untuk menghambat pertumbuhan adalah 0,060 g/ml, untuk kedua spesies bakteri. Variasi perlakuan pada uji cakram kertas yaitu konsentrasi A (0,065 g/ml, B (0,070 g/ml, C (0,075 g/ml, D (0,080 g/ml, E (0,085 g/ml, F (0,090 g/ml dan kontrol (0,000 g/ml, hasil yang diperoleh adalah konsentrasi 0,090 g/ml memiliki diameter zona hambat tertinggi sebesar 11,17 ± 0,5 mm (V. harveyi dan 12,53 ± 1,14 mm (V. alginolyticus, sehingga dapat disimpulkan bahwa buah adas (F. vulgare Mill memiliki peranan ekologi yang sangat penting sebagai bahan pengobatan alternatif dalam pengendalian penyebaran penyakit Vibriosis yang disebabkan oleh V. harveyi dan V. alginolyticus. Kata kunci: Foeniculum vulgare Mill, Vibrio harveyi, Vibrio alginolyticus, uji MIC dan difusi cakram kertas

  2. Adult Autism Subthreshold Spectrum (AdAS Spectrum) in parents of pediatric patients with epilepsy: Correlations with post-traumatic stress symptoms.

    Science.gov (United States)

    Dell'Osso, L; Corsi, M; Gesi, C; Bertelloni, C A; Massimetti, G; Peroni, D; Bonuccelli, A; Orsini, A; Carmassi, C

    2018-05-01

    Increasing literature has shown the usefulness of a dimensional approach to mental disorders, particularly when exploring subjects exposed to traumatic experiences such as a severe illness in one's child. Recent evidence suggests an increased vulnerability in subjects with autism spectrum symptoms to develop post-traumatic stress symptoms. The aim of the present study was to evaluate the presence of adult autism subthreshold spectrum in a sample of parents of children with epilepsy and its impact on post-traumatic stress spectrum symptoms in the same study sample. Results revealed noteworthy correlations between post-traumatic stress symptoms and adult autism subthreshold spectrum (AdAS Spectrum) only in the subgroup of the fathers. In particular, were evidenced correlations between AdAS Spectrum domain of rumination and narrow interests and some TALS-SR nuclear domains: reaction to traumatic events, reexperiencing and arousal. These findings corroborate the hypothesis that subthreshold autistic features may influence the possible psychopathological reaction to trauma. Copyright © 2018 Elsevier Inc. All rights reserved.

  3. A Clinical Practice Update on the Latest AAOS/ADA Guideline (December 2012) on Prevention of Orthopaedic Implant Infection in Dental Patients.

    Science.gov (United States)

    Hamedani, Sh

    2013-03-01

    The American Academy of Orthopaedic Surgeons (AAOS) and the American Dental Association (ADA), along with 10 other academic associations and societies recently (December 2012) published their mutual clinical practice guideline "Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures." This evidence-based guideline ,detailed in 325 pages, has three recommendations and substitutes the previous AAOS guideline. The new published clinical guideline is a protocol to prevent patients undertaking dental procedures from orthopaedic implant infection. The guideline is developed on the basis of a collaborative systematic review to provide practical advice for training clinicians, dentists and any qualified physicians who need to consider prevention of orthopaedic implant (prosthesis) infection in their patients. This systematic review found no explicit evidence of cause-and-effect relationship between dental procedures and periprosthetic joint infection (PJI). This LTTE wishes to present a vivid summary of AAOS/ADA clinical practice guideline as a clinical update and an academic implementation to inform and assist Iranian competent clinicians and dentists in the course of their treatment decisions, to enrich the value and quality of health care on the latest international basis.

  4. Projeto, produção e execução de edificações com lajes pré-moldadas treliçadas

    Directory of Open Access Journals (Sweden)

    J. R. Figueiredo Filho

    Full Text Available O emprego de lajes pré-moldadas treliçadas nas estruturas de concreto armado ganhou impulso a partir dos anos 90. Sua construção passa por duas etapas principais: uma industrial na fabricação das joists treliçadas e outra, na obra, quando recebe o concreto para a confecção da capa. Seu uso se justifica pelas vantagens que apresenta em relação a outros sistemas, tais como a redução do consumo de materiais e da mão-de-obra, facilidade, agilidade e rapidez na execução, praticidade na confecção de instalações prediais, alívio do peso próprio da estrutura, versatilidade de aplicação e economia. Analisam-se os procedimentos de fabricação das joists e montagem dessas lajes em diversos tipos de edificações na região de São Carlos, São Paulo, além de feitas entrevistas com fabricantes, projetistas e construtores. Verificou-se que o sistema tem sido executado na maioria das vezes de maneira inadequada, sem cuidados simples que, se adotados, certamente melhorariam em muito os problemas de qualidade e durabilidade que quase sempre surgem na fase de utilização.

  5. Estruturas de concreto reforçadas com PRFC Parte I: análise dos modelos de flexão

    Directory of Open Access Journals (Sweden)

    A. L. Gamino

    Full Text Available Este trabalho, apresentado em duas partes, trata da avaliação dos modelos de projeto de estruturas de concreto armado reforçadas com Polímeros Reforçados com Fibras de Carbono (PRFC. Nesta primeira parte são avaliados modelos de flexão originados das recomendações ACI-440 e fib-14, assim como outros modelos mais recentes, disponíveis na literatura. Esses critérios foram aplicados a um total de vinte e cinco vigas reforçadas à flexão, ensaiadas pelos autores, das quais dezesseis com seção retangular e nove com seção "T". Foram aplicados diferentes tipos de compósitos de fibras de carbono (tecidos e laminados, de diferentes fabricantes, encontrados no mercado brasileiro. Os resultados obtidos mostram uma boa proximidade entre as cargas de ruptura calculadas de acordo com as recomendações ACI-440 para reforços à flexão e os valores observados nos ensaios.

  6. Lower frequency of the low activity adenosine deaminase allelic variant (ADA1*2 in schizophrenic patients Diminuição da frequência da variante alélica de baixa atividade da adenosina desaminase (ADA1*2 em pacientes esquizofrênicos

    Directory of Open Access Journals (Sweden)

    Gustavo Pimentel Dutra

    2010-09-01

    Full Text Available OBJECTIVE: Adenosine may play a role in the pathophysiology of schizophrenia, since it modulates the release of several neurotransmitters such as glutamate, dopamine, serotonin and acetylcholine, decreases neuronal activity by pos-synaptic hyperpolarization and inhibits dopaminergic activity. Adenosine deaminase participates in purine metabolism by converting adenosine into inosine. The most frequent functional polymorphism of adenosine deaminase (22G→A (ADA1*2 exhibits 20-30% lower enzymatic activity in individuals with the G/A genotype than individuals with the G/G genotype. The aim of this study was to evaluate the ADA polymorphism 22G→A (ADA1*2 in schizophrenic patients and healthy controls. METHOD: The genotypes of the ADA 22G→A were identified with allele-specific PCR strategy in 152 schizophrenic patients and 111 healthy individuals. RESULTS: A significant decrease in the frequency of the G/A genotype was seen in schizophrenic patients (7/152 - 4.6% relative to controls (13/111 - 11.7%, p = 0.032, OR = 2.6. CONCLUSION: These results suggest that the G/A genotype associated with low adenosine deaminase activity and, supposingly, with higher adenosine levels is less frequent among schizophrenic patients.OBJETIVO: A adenosina pode ter um papel importante na fisiopatologia da esquizofrenia, uma vez que modula a liberação de vários neurotransmissores, tais como glutamato, dopamina, serotonina e acetilcolina, diminui a atividade neuronal por hiperpolarização pós-sináptica e inibe a atividade dopaminérgica. A adenosina desaminase participa do metabolismo das purinas pela conversão de adenosina em inosina. O mais frequente polimorfismo funcional da adenosina desaminase (22G →A (ADA1*2 exibe uma diminuição de 20-30% da atividade funcional em indivíduos com genótipo G/A quando comparados com indivíduos com o genótipo G/G. O objetivo deste estudo foi avaliar o polimorfismo 22G→A (ADA1*2 em pacientes esquizofrênicos e em

  7. A systematic study of the effect of low pH acid treatment on anti-drug antibodies specific for a domain antibody therapeutic: Impact on drug tolerance, assay sensitivity and post-validation method assessment of ADA in clinical serum samples.

    Science.gov (United States)

    Kavita, Uma; Duo, Jia; Crawford, Sean M; Liu, Rong; Valcin, Joan; Gleason, Carol; Dong, Huijin; Gadkari, Snaehal; Dodge, Robert W; Pillutla, Renuka C; DeSilva, Binodh S

    2017-09-01

    We developed a homogeneous bridging anti-drug antibody (ADA) assay on an electro chemiluminescent immunoassay (ECLIA) platform to support the immunogenicity evaluation of a dimeric domain antibody (dAb) therapeutic in clinical studies. During method development we evaluated the impact of different types of acid at various pH levels on polyclonal and monoclonal ADA controls of differing affinities and on/off rates. The data shows for the first time that acids of different pH can have a differential effect on ADA of various affinities and this in turn impacts assay sensitivity and drug tolerance as defined by these surrogate controls. Acid treatment led to a reduction in signal of intermediate and low affinity ADA, but not high affinity or polyclonal ADA. We also found that acid pretreatment is a requisite for dissociation of drug bound high affinity ADA, but not for low affinity ADA-drug complexes. Although we were unable to identify an acid that would allow a 100% retrieval of ADA signal post-treatment, use of glycine pH3.0 enabled the detection of low, intermediate and high affinity antibodies (Abs) to various extents. Following optimization, the ADA assay method was validated for clinical sample analysis. Consistencies within various parameters of the clinical data such as dose dependent increases in ADA rates and titers were observed, indicating a reliable ADA method. Pre- and post-treatment ADA negative or positive clinical samples without detectable drug were reanalyzed in the absence of acid treatment or presence of added exogenous drug respectively to further assess the effectiveness of the final acid treatment procedure. The overall ADA results indicate that assay conditions developed and validated based on surrogate controls sufficed to provide a reliable clinical data set. The effect of low pH acid treatment on possible pre-existing ADA or soluble multimeric target in normal human serum was also evaluated, and preliminary data indicate that acid type and

  8. Detecting Treatment Group Differences in Alzheimer's Disease Clinical Trials: A Comparison of Alzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-Cog) and the Clinical Dementia Rating - Sum of Boxes (CDR-SB).

    Science.gov (United States)

    Wessels, A M; Dowsett, S A; Sims, J R

    2018-01-01

    The Alzheimer's Disease Assessment Scale's cognitive subscale (ADAS-Cog) has been widely used as an outcome measure in Alzheimer's Disease (AD) clinical trials. In its original form (ADAS-Cog11), the scale has been used successfully in mild-to-moderate AD dementia populations, but its use is more limited in the study of earlier disease (mild cognitive impairment [MCI] or mild dementia due to AD) owing to lack of appropriate sensitivity of some items. With recent focus on earlier treatment, efforts have focused on the development of more sensitive tools, including the Clinical Dementia Rating-Sum of Boxes (CDR-SB), a global assessment tool to evaluate both cognition and function. The ability of the ADAS-Cog and CDR-SB to detect treatment group differences in the clinical trial environment has not been systematically studied. The aim of this analysis was to compare the utility of these tools in detecting treatment group differences, by reviewing study findings identified through advanced searches of clinicaltrials.gov and Ovid, and press releases and scientific presentations. Findings from placebo-controlled studies of ≥ 6m duration and enrolling >100 participants were included; reporting of both the ADAS-Cog and CDR-SB at endpoint was also a requirement. Of the >300 records identified, 34 studies fulfilled the criteria. There were significant placebo versus active drug group differences based on findings from at least one measure for 14 studies. The ADAS-Cog detected treatment differences more frequently than the CDR-SB. Based on these and previously published findings, the ADAS-Cog appears more useful than the CDR-SB in detecting treatment group differences.

  9. Estudo exaustivo e sistemático de erros nas provas da olimpíada brasileira de astronomia - resultados preliminares

    Science.gov (United States)

    Oliveira, F. S.; Canalle, J. B. G.; Villas da Rocha, J. F.

    2003-08-01

    A Olimpíada Brasileira de Astronomia (OBA) contou, em sua quinta edição, com a participação de mais de 60 mil alunos dos ensinos fundamental e médio de praticamente todo o território nacional. Uma das formas de controle que a sua coordenação nacional possui sobre a correção, levada a cabo pelos professores que as aplicaram, é a do envio, por parte destes professores, das 10 melhores provas de cada um dos três níveis nos quais a Olimpíada é realizada. Assim, e dado ao caráter discursivo das provas da Olimpíada, a sua coordenação nacional dispõe de um vasto acervo sobre as concepções, certas ou erradas, dos alunos que dela participaram. Este conjunto de dados jamais fora explorado até o presente trabalho que pretende ser, neste sentido, inaugural. Nas provas dos níveis I e II da V OBA, que abrangem todo o conjunto do ensino fundamental, uma das questões versava sobre a noção que os alunos tinham sobre como os habitantes da Terra situam-se sobre sua superfície. Fizemos um estudo sistemático das respostas a esta questão. Primeiramente, todas as modalidades de erros foram levantadas; em seguida, realizamos uma distribuição por idade tanto do índice de acerto como da ocorrência e da distribuição de cada erro. Como resultado, obtivemos que, em ambos os níveis: 1) as concepções errôneas não se apresentam distribuídas aleatoriamente; 2) há uma concentração no tipo de erro apresentado; 3) há uma tendência de progressivo acerto com relação à idade quando os dados são considerados em termos nacionais; 4) esta tendência nacional é fraca ou mesmo não é verificada em alguns dos estados com maior patamar de acerto.

  10. Papel dos níveis de BNP no prognóstico da insuficiência cardíaca avançada descompensada

    Directory of Open Access Journals (Sweden)

    Antônio Carlos Pereira-Barretto

    2013-03-01

    Full Text Available FUNDAMENTO: A insuficiência cardíaca (IC é doença que cursa com má evolução, especialmente naqueles com IC avançada. A dosagem de peptídeo natriurético tipo B(BNP, ao lado da utilidade no diagnóstico da descompensação cardíaca, vem se mostrando útil na avaliação prognóstica. OBJETIVOS: Verificar se os níveis de BNP identificam quais pacientes evoluiriam pior e se o BNP seria fator independente de mortalidade considerando-se idade, sexo, funções cardíaca e renal e etiologia da cardiopatia. MÉTODOS: 189 pacientes com IC avançada em classe funcional III/IV foram estudados. Todos tinham disfunção sistólica e dosaram-se os níveis de BNP na hospitalização. Analisaram-se as variáveis relacionadas com a mortalidade através de análises univariada e multivariada. RESULTADOS: Os níveis de BNP foram mais elevados nos pacientes que morreram no primeiro ano de seguimento (1.861,9 versus 1.408,1 pg/dL; p = 0,044 e nos chagásicos (1.985 versus 1.452 pg/mL; p = 0,001, e esses pacientes chagásicos tiveram maior mortalidade no primeiro ano de seguimento (56% versus 35%; p = 0,010. Pela curva ROC, o valor de BNP de 1.400 pg/mL foi o melhor preditor de eventos, estando os valores elevados associados a FEVE mais baixa (0,23 versus 0,28; p = 0,002 e maior grau de disfunção renal (ureia média 92 versus 74,5 mg/dL; p = 0,002. CONCLUSÃO: Na IC avançada, os níveis elevados de BNP identificam pacientes com maior potencial de pior evolução. Os pacientes chagásicos apresentam níveis mais elevados de BNP do que as outras etiologias e têm pior evolução.

  11. Avaliação do desempenho estrutural em serviço de lajes treliçadas pré-moldadas de concretos com agregados leves

    OpenAIRE

    Oliveira,Anderson de; Garcia,Sergio Luis González; Cordeiro,Guilherme Chagas

    2011-01-01

    O concreto com agregado leve tem sido cada vez mais empregado em razão da reduzida massa específica, do elevado isolamento térmico e acústico e da melhoria na resistência estrutural a carregamentos cíclicos. Neste trabalho foram estudados concretos com agregados leves com resistência à compressão em torno de 20 MPa e seu desempenho estrutural em lajes treliçadas pré-moldadas. Utilizaram-se três diferentes concretos com valores de massa específica entre 1.200 e 1.600 kg/m³. Os concretos foram ...

  12. Análise e caracterização das questões das provas da Olimpíada Brasileira de Física

    Directory of Open Access Journals (Sweden)

    Joao Paulo Casaro Erthal

    2014-07-01

    Full Text Available http://dx.doi.org/10.5007/2175-7941.2015v32n1p142 No Brasil, anualmente, são organizadas e praticadas olimpíadas escolares em diversas áreas do conhecimento, tais como: língua portuguesa, matemática, biologia, física, entre outras. A Olimpíada Brasileira de Física (OBF tem como objetivo despertar e estimular nos estudantes o interesse pela física, proporcionando desafios e incentivando-os a seguir carreiras científicas e tecnológicas. Este trabalho visa investigar os conteúdos exigidos nas provas da OBF e a forma como estes são abordados, com a finalidade de traçar um perfil das provas da OBF, aplicadas aos estudantes do ensino médio. Para isso, realizou-se uma análise das questões das provas do período de 1999 a 2013, distribuindo os conteúdos das questões das provas em seis áreas de conhecimento da física: mecânica, ondulatória, física térmica, eletromagnetismo, óptica geométrica e física moderna. Após a análise foram construídos gráficos que auxiliaram a identificar peculiaridades destas provas. Os resultados mostram uma evolução no perfil da prova, que atualmente possui uma abordagem mais contextualizada e interdisciplinar quando comparada às edições anteriores, em consonância ao que está descrito nos documentos oficiais da educação brasileira.

  13. Pokročilé asistenční systémy (ADAS) – optika ve službách bezpečnosti silničního provozu

    Czech Academy of Sciences Publication Activity Database

    Viktorová, L.; Stanke, Ladislav

    2017-01-01

    Roč. 62, Sep-Oct (2017), s. 216-222 ISSN 0447-6441 Institutional support: RVO:68378271 Keywords : ADAS * automotive * LIDAR * sensors * traffic psychology * driver behaviour * traffic safety Subject RIV: AN - Psychology OBOR OECD: Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

  14. Protocolo de cooperação entre o Centro de Formação Profissional da Indústria de Construção Civil e Obras Públicas do Sul e a Universidade Lusíada

    OpenAIRE

    Universidade Lusíada de Lisboa; Centro de Formação Profissional da Indústria de Construção Civil e Obras Públicas do Sul

    2013-01-01

    Data da assinatura: 3 de Novembro de 1998 Troca de informação e experiências, estudo, preparação e lançamento de técnicas nos domínios das tecnologias da arquitectura, dirigido fundamentalmente aos alunos finalistas da Universidade Lusíada.

  15. rCBF and cognitive impairment changes assessed by SPECT and ADAS-cog in late-onset Alzheimer's disease after 18 months of treatment with the cholinesterase inhibitors donepezil or galantamine.

    Science.gov (United States)

    Shirayama, Yukihiko; Takahashi, Michio; Oda, Yasunori; Yoshino, Kouhei; Sato, Koichi; Okubo, Toshiyuki; Iyo, Masaomi

    2017-12-15

    Late-onset Alzheimer's disease (AD) differs substantially from early-onset AD. In this cross sectional study we investigated brain perfusion changes after 18 months of treatment with cholinesterase inhibitors (ChEIs) donepezil or galantamine. Twenty-five drug-naïve late-onset AD patients were recruited from outpatient clinics. We examined brain perfusion using single photon emission computed tomography (SPECT) and used three-dimensional stereotactic surface projection (3D-SSP) and the stereotactic extraction estimation method (SEE) level 3 to analyze classified gyrus level segments. We assessed cognitive function using the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) grouped into three subgroup domains, language, memory, and praxis. In the follow-up data, some regions were further hypoperfused, reflecting worsening of the disease, while other regions showed alleviated hypoperfusion, potentially related to the ChEIs treatment. Regional cerebral blood flow (rCBF) decreased in the parietal cortex and increased in the frontal and the limbic cortices. Increased hypoperfusion significantly correlated with ADAS-cog scores changes were seen in the superior parietal lobule, inferior parietal lobule, angular gyrus, and supramarginal gyrus of the parietal cortex. Alleviated hypoperfusion significantly related to recovery of ADAS-cog scores were seen in the rectal and paracentral lobule of the frontal cortex, and the anterior cingulate of the limbic cortex. These regions showed significant relationships with total ADAS-cog and language, memory and praxis subscales scores. The current longitudinal study indicates prominent rCBF changes and their relationships with changes in ADAS-cog scores in late-onset AD patients.

  16. Torta de mamona não destoxificada na indução da muda forçada em poedeiras comerciais

    Directory of Open Access Journals (Sweden)

    K.S.M. Mucida

    2014-08-01

    Full Text Available Avaliou-se o uso de dietas com diferentes porcentagens de torta de mamona não destoxificada (TM na indução da muda forçada, sendo utilizadas 120 poedeiras Lohman LSL de 81 semanas, distribuídas ao acaso em quatro tratamentos, com cinco repetições de seis aves. Um dos tratamentos consistiu na indução da muda pelo método do jejum por 11 dias, e os demais no uso de dietas de muda, compostas pela mistura de dieta de postura e TM nas quantidades de 20, 30 e 40%, por até 21 dias ou até quando as aves atingissem 23% de perda do peso. Diferenças significativas foram observadas nos eritrócitos, no hematócrito, na concentração média de hemoglobina globular, na proteína total do plasma, nos leucócitos e na alanina aminotransferase, medidos durante a indução da muda, bem como no desempenho das aves após a muda, no que diz respeito ao consumo de ração, à porcentagem de postura, ao peso do ovo, à massa do ovo e à conversão alimentar. A qualidade dos ovos não variou estatisticamente entre os métodos avaliados. A utilização da dieta de muda forçada contendo 40% de TM promoveu resultados semelhantes aos obtidos com o método do jejum, tanto para consumo de ração, porcentagem de postura, peso do ovo, massa do ovo, e conversão alimentar, como inerentes à qualidade dos ovos, quanto para densidade específica, unidade Haugh, porcentagens de gema, casca e albúmen. No entanto, menores alterações nos valores de eritrócitos, hematócrito e alanina aminotransferase foram observadas nesse método supracitado. O uso da dieta de muda contendo 40% de TM mostrou-se uma alternativa viável ao uso do método do jejum.

  17. Qualidade dos produtos de terapias avançadas: requisitos de células extensamente manipuladas usadas em terapias celulares e em bioengenharia

    Directory of Open Access Journals (Sweden)

    Rosana Bizon Carias

    2018-02-01

    Full Text Available Introdução: O preparo de produtos para terapias avançadas inclui, frequentemente, a manipulação extensa de células primárias in vitro, o que pode acarretar em alterações da população celular final. A padronização dos métodos de obtenção das culturas, seguindo as regras das Boas Práticas de Fabricação, com a realização dos controles de qualidade do processo e do produto final, é essencial para garantir a segurança do paciente e a comparabilidade dos resultados clínicos obtidos. Objetivo: Este estudo buscou identificar os ensaios, prevalentemente citados na literatura científica ou em normas sanitárias, aplicados na avaliação da qualidade de células primárias humanas, passíveis de serem inseridos na rotina dos Centros de Processamento Celular. Método: Foi realizado o levantamento de artigos científicos e de normas sanitárias que tratassem de terapia celular e dos ensaios de qualidade associados. Resultados: Foi evidenciado que as normas regulamentares direcionadas a produtos com base em células cultivadas in vitro não detalham os ensaios de qualidade, o que torna urgente a discussão dessa matéria. Conclusões: Evidenciamos a necessidade de preparo do produto na forma de um lote de células, que deve ser controlado para a qualidade, a partir de amostras representativas do todo e propomos a realização de uma bateria de ensaios, que definem a qualidade do produto de terapia avançada, a base de células cultivadas in vitro, com detalhamento dos pontos em que estes devem ser realizados, organizados como fluxogramas de processamento.

  18. Vigas de concreto reforçadas com bambu Dendrocalamus giganteus. I: análise experimental Concrete beams reinforced with bamboo (Dendrocalamus giganteus. I: experimental analysis

    Directory of Open Access Journals (Sweden)

    Humberto C. Lima Júnior

    2005-12-01

    Full Text Available Neste trabalho, apresenta-se e se discute um estudo experimental sobre o comportamento estrutural de vigas de concreto reforçadas com bambu. Ensaiaram-se dez vigas de concreto armado, sendo oito vigas armadas longitudinalmente com varas de bambu Dendrocalamus giganteus e duas vigas de referência, armadas com barras de aço. Duas variáveis foram estudadas: a taxa de armadura longitudinal (1,6 e 3,2% e a relação área/perímetro das varas de bambu (0,25 e 0,33 cm. Para cada combinação de variáveis foram confeccionadas duas vigas. Curvas força vs. deslocamento e força vs. deformação dos materiais são apresentadas e discutidas. Constatou-se que o comportamento estrutural das vigas de concreto reforçadas com bambu segue a teoria de flexão de Bernoulli-Kirchoff, sendo possível a aplicação dos procedimentos usuais de dimensionamento do concreto armado no projeto desses elementos. Observou-se, também, que a capacidade de carga dessas vigas se assemelha à das vigas de aço; contudo, estas são mais rígidas que aquelas.In this paper, an experimental study about bamboo reinforced concrete beams is presented and discussed. Ten reinforced concrete beams were tested, where eight of them were reinforced with Dendrocalamus giganteus bamboo-splint and two reference beams were reinforced with steel bars. Two factors were studied: the longitudinal reinforcement ratio (1.6 and 3.2% and the area/perimeter ratio of the bamboo-splint (0.25 and 0.33 cm. For each factor combination, two beams were cast. Force vs. displacement and force vs. strain curves are presented and discussed. It was found out that the structural behaviour of bamboo-concrete beams follow the Bernoulli-Kirchoff bending theory. Therefore, the usual design procedures of reinforced concrete can be used to design the bamboo-concrete beams. The load capacity of the bamboo-concrete beams is almost the same as that of reinforced with steel; nevertheless, are more stiffer than those

  19. Comportamento estrutural de vigas de concreto reforçadas com ripas de bambu cravejadas de pinos Structural behavior of concrete beams reinforced with pinned bamboo-splints

    Directory of Open Access Journals (Sweden)

    Antonio C. Braga Filho

    2010-10-01

    Full Text Available Uma das deficiências do bambu reforçando vigas de concreto armado está relacionada com deslocamentos relativos entre os dois materiais. A investigação aqui reportada teve como objetivo avaliar experimentalmente a possibilidade de se melhorar o trabalho conjunto bambu-concreto, através do cravejamento de pinos nas ripas de bambu usadas como reforço. Para tanto, oito vigas de concreto foram ensaiadas, das quais seis foram reforçadas com ripas de bambu Dendrocalamus giganteus Munro cravejadas de pinos e duas armadas com ripas de bambu sem a presença dos pinos, como referência. Usaram-se dois tipos de pino: de aço ou de bambu, em número de dois, três ou quatro pinos entre nós. Curvas força-deslocamento e força-deformação dos materiais são apresentadas e discutidas, em que os resultados mostraram que a cravação dos pinos produziu um aumento de rigidez das vigas; contudo, o furo feito para colocação do pino reduziu localmente a seção transversal da ripa de bambu e, consequentemente, a resistência última das vigas. Finalmente, resultados similares foram obtidos em vigas reforçadas com pino de aço ou de bambu.One drawback of bamboo as concrete reinforcement beams is the relative displacement between the two materials. The research reported in this paper aimed to experimentally investigate the improvement of bamboo-concrete-bond by means of nailing. Eight concrete beams were tested, six of them reinforced with Dendrocalamus giganteus Munro nailed bamboo-splints and two reference beams, reinforced with bamboo-splints without pins. Steel pins or bamboo pins were used. Two, three and four pins were nailed between bamboo nodes. Load-displacement and load-strain curves are presented and discussed. The results showed that the pins improved the beam stiffness; nevertheless, they reduced locally the transversal section of the bamboo splint and, consequently, the ultimate load. Finally, similar results were showed by beams reinforced

  20. Notas sobre lógica e dialética na Enéada de Plotino Notes on logic and dialectic in Enneads of Plotino

    Directory of Open Access Journals (Sweden)

    Loraine Oliveira

    2007-01-01

    Full Text Available Este trabalho objetiva caracterizar a lógica e a dialética, conforme a Enéada I, 3 [20] 4-5. Para Plotino, a lógica consiste em um conjunto de procedimentos que trata de proposições e silogismos. A dialética é um método que faz uso dos procedimentos lógicos. Mas é também uma disposição que permite compreender a estrutura do inteligível. Por conseguinte, é um caminho de ascensão rumo ao Uno. Neste sentido, tem um aspecto ético.This article aims to characterize logic and dialectic in Enneads I, 3 [20] 4-5. For Plotin, logic is a whole of proceedings that deals with propositions and syllogisms whereas dialectic is a method that employs logical proceedings. Nevertheless, dialectic is also an disposition through which the structure of the intelligible can be understood. So, it is a way towards the One. Thus, it has a ethical aspect.

  1. Avaliação do desempenho estrutural em serviço de lajes treliçadas pré-moldadas de concretos com agregados leves

    Directory of Open Access Journals (Sweden)

    Anderson de Oliveira

    Full Text Available O concreto com agregado leve tem sido cada vez mais empregado em razão da reduzida massa específica, do elevado isolamento térmico e acústico e da melhoria na resistência estrutural a carregamentos cíclicos. Neste trabalho foram estudados concretos com agregados leves com resistência à compressão em torno de 20 MPa e seu desempenho estrutural em lajes treliçadas pré-moldadas. Utilizaram-se três diferentes concretos com valores de massa específica entre 1.200 e 1.600 kg/m³. Os concretos foram avaliados com relação à resistência à compressão (aos 3, 7 e 28 dias e à absorção total de água (aos 28 dias. Com os três tipos de concreto foram produzidas e ensaiadas à flexão lajes pré-moldadas (duas lajes para cada tipo de concreto, com a avaliação de seu comportamento no estado limite de serviço (ELS para cargas de curta duração, ou seja, sem considerar efeitos ao longo do tempo. Os resultados mostraram o potencial do uso de concretos com agregados leves nesse tipo de laje estrutural.

  2. CEINCI-LAB un software libre para hallar la curva de capacidad sísmica de pórticos con disipadores ADAS o TADAS

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    Roberto Aguiar

    Full Text Available CEINCI-LAB es un sistema de computación desarrollado en MATLAB que permite realizar el análisis estático o dinámico de estructuras, en forma amigable y a la vez sirve para que el usuario pueda afianzar sus conocimientos estructurales. En este artículo se presentan los aspectos más importantes para hallar la curva de capacidad sísmica resistente de un pórtico plano de hormigón armado o de acero, con disipadores de energía ADAS o TADAS que se hallan sobre contravientos Chevrón, empleando la Técnica del Pushover. Para el conjunto contraviento-disipador se presentan dos modelos de análisis, el uno es mediante dos diagonales equivalentes y en el otro al elemento disipador se lo considera como un elemento corto. Para éste último caso, el elemento disipador es analizado de dos maneras, en la primera se encuentra la matriz de rigidez del elemento disipador y en la segunda se consideran varias dovelas rectangulares de sección constante para el elemento disipador.

  3. BIOMETRIC STUDY OF COMMERCIAL ALAYING HENS SUBMITTED TO THE PROGRAMS OF FORCED MOLTING BIOMETRIA DO INTESTINO DE POEDEIRAS COMERCIAIS SUBMETIDAS A PROGRAMAS DE MUDA FORÇADA

    Directory of Open Access Journals (Sweden)

    Lizandra Amoroso

    2008-12-01

    Full Text Available The forced molting in commercial laying hens had being utilized for get better the performance of birds for one more cycle of production of eggs. The experiment was aimed at evaluating the intestinal biometric parameters in laying hens submitted to the different forced molting program. Third two Hisex Brown laying hen with 58 weeks of age were  randomly subdivided into four programs (P1- California program; P2- diet of low-calcium; T3- diet of high-zinc and P4- diet of low-sodium in two replications constituted of four birds each. The biometric parameters occurred at 28th and 140nd days and for this, four birds were sacrificed of each program in the period cited. The bird corporal weight and the relative weight of the intestine (duodenum, jejunum, ileum, cecum and rectum were obtained on electronic precision scales and the lengths were measured. The data were submitted to the variance analysis and in case of significant difference; the averages were compared by the Tukey´s test. It was observed the commercial laying P1 and P3 the smallest mean body and relative weights (no significant and lengths in relation to the chickens P2 and P4 and to the 140th days the corporal weight, relative weight and length of the intestine of chickens were larger. Concluded that the different programs of forced molting presented similar results and they can be used for commercial laying hens in second production cycle.

    KEY WORDS: Digestory system, nutricional manage, physiology, postmolt.
    A muda forçada em poedeiras comerciais tem sido utilizada para melhorar o desempenho zootécnico das aves por mais um ciclo de produção de ovos. O experimento foi realizado com o objetivo de avaliar a biometria do intestino de poedeiras comerciais submetidas a diferentes programas de muda forçada. Trinta e duas aves da linhagem Hisex Brown com 58 semanas de idade foram distribuídas em um delineamento inteiramente casualizado, constando de quatro programas de

  4. Vantagens e desafios das biotécnicas avançadas utilizadas na reprodução equina assistida

    Directory of Open Access Journals (Sweden)

    Beatriz Ramos Bertozzo

    2014-01-01

    Full Text Available Relatos apontam que a espécie equina foi a primeira a ser submetida à inseminação artificial. Apesar deste fato, o desenvolvimento da reprodução assistida nos equinos foi lento em comparação às demais espécies voltadas diretamente para a produção animal. A liberação do uso da transferência de embriões pela maioria das associações de raças estimulou o desenvolvimento e a expansão de algumas técnicas de multiplicação animal para uso em equinos. A presente revisão teve por objetivo abordar as biotécnicas avançadas atualmente disponíveis para a espécie, como a superovulação, a transferência de ovócitos, a transferência intratubárica de gametas, a injeção intracitoplasmática de gametas, a produção in vitro de embriões e a clonagem, enfatizando suas aplicações prática e clínica, bem como determinados desafios que ainda precisam ser superados em cada biotécnica.

  5. O mito das Olimpíadas: Hesíodo, Bacon, Hobbes e a infindável luta dos titãs

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Santos da Silva

    2016-08-01

    Full Text Available O presente artigo tem por objetivo apresentar alguns dos aspectos mitológicos que fundamentam a realização das olimpíadas desde a antiguidade grega, particularmente a “corrida de tochas acessas” que atualmente inaugura a abertura dos jogos. Para tanto, buscamos apresentar alguns relatos que narram a realização dos jogos olímpicos como uma espécie memória aos mitos fundadores da cultura grega. Nesse registro, consideramos alguns aspectos das narrativas de Hesíodo sobre o mito de Prometeu, bem como algumas observações de filósofos modernos como Francis Bacon e Thomas Hobbes sobre como essa fábula narra a interpretação de uma condição humana fundada em uma competição análoga à uma interminável luta de titãs. Condição humana essa oriunda da desobediência às vontades dos deuses do Olimpo, cristalizada na expressão de uma cultura da competição que visa não apenas agradar a esses deuses, detentores do poder no Olimpo, mas também igualar certos homens a eles.

  6. Efetividade dos inibidores dos produtos finais da glicação avançada na prevenção da progressão da nefropatia diabética

    OpenAIRE

    Lemos, André Luis Alves de [UNIFESP

    2007-01-01

    Objetivo: O propósito desta revisão sistemática foi avaliar a progressão da nefropatia diabética em indivíduos recebendo inibidores dos produtos finais da glicação avançada. Métodos: Tipos de estudos: ensaios clínicos randomizados; tipos de participantes: pacientes com nefropatia diabética (estágios 1 a 4); intervenção: uso dos inibidores dos produtos finais da glicação avançada associado à terapia convencional (inibidores da enzima conversora de angiotensina e/ou antagonistas do recept...

  7. Effects of memantine on cognition in patients with moderate to severe Alzheimer's disease: post-hoc analyses of ADAS-cog and SIB total and single-item scores from six randomized, double-blind, placebo-controlled studies.

    Science.gov (United States)

    Mecocci, Patrizia; Bladström, Anna; Stender, Karina

    2009-05-01

    The post-hoc analyses reported here evaluate the specific effects of memantine treatment on ADAS-cog single-items or SIB subscales for patients with moderate to severe AD. Data from six multicentre, randomised, placebo-controlled, parallel-group, double-blind, 6-month studies were used as the basis for these post-hoc analyses. All patients with a Mini-Mental State Examination (MMSE) score of less than 20 were included. Analyses of patients with moderate AD (MMSE: 10-19), evaluated with the Alzheimer's disease Assessment Scale (ADAS-cog) and analyses of patients with moderate to severe AD (MMSE: 3-14), evaluated using the Severe Impairment Battery (SIB), were performed separately. The mean change from baseline showed a significant benefit of memantine treatment on both the ADAS-cog (p ADAS-cog single-item analyses showed significant benefits of memantine treatment, compared to placebo, for mean change from baseline for commands (p < 0.001), ideational praxis (p < 0.05), orientation (p < 0.01), comprehension (p < 0.05), and remembering test instructions (p < 0.05) for observed cases (OC). The SIB subscale analyses showed significant benefits of memantine, compared to placebo, for mean change from baseline for language (p < 0.05), memory (p < 0.05), orientation (p < 0.01), praxis (p < 0.001), and visuospatial ability (p < 0.01) for OC. Memantine shows significant benefits on overall cognitive abilities as well as on specific key cognitive domains for patients with moderate to severe AD. (c) 2009 John Wiley & Sons, Ltd.

  8. Geochemical study of two obsidian production centers in the Prehistory of Tenerife: El Tabonal de los Guanches (Icod de los Vinos) and el Tabonal Negro (Las Cañadas)

    OpenAIRE

    Hernández Gómez, Cristo M.; Galván Santos, Bertila

    2008-01-01

    The obsidian production is one of the work processes that allow a good characterization of the Guanches, first inhabitants of Tenerife (Canary Islands). On this occasion, addresses the geochemical study of the volcanic flows where the main obsidian sources of the Aboriginal of Tenerife are located: The Tabonal de Los Guanches (Icod de Los Vinos) and the Tabonal Negro, Mña. Blanca (Las Cañadas del Teide) characterized as Production Centres. The aim is to establish the compositional differences...

  9. Segundo termo aditivo [ao] Acordo de cooperação cultural, educacional e científico entre a Universidade Presbiteriana Mackenzie - UPM e Universidades Lusíada

    OpenAIRE

    Universidade Lusíada de Lisboa; Universidade Lusíada do Porto; Universidade Lusíada de Vila Nova de Famalicão; Universidade Presbiteriana Mackenzie

    2014-01-01

    Data da assinatura: 22 de outubro de 2014 Promover a cooperação académica entre as Faculdades de Arquitectura e Artes das Universidades Lusíada e a Faculdade de Arquitectura e Urbanismo da Universidade Presbiteriana Mackenzie, através do reconhecimento mútuo de formação em vista da possível outorga de dupla titulação.

  10. Terapia de Interacción Guiada en díadas madre-bebé con sintomatología depresiva materna en el embarazo: un estudio piloto

    Directory of Open Access Journals (Sweden)

    Marcia Paola Olhaberry Huber

    2015-11-01

    Full Text Available La depresión perinatal constituye un trastorno del ánimo de alta frecuencia, que afecta negativamente a la madre y al bebé, y requiere una intervención dirigida a ambos miembros de esta díada. Esta investigación evalúa la aplicabilidad y resultados de una intervención piloto dirigida a fortalecer el vínculo y a reducir la depresión en díadas con esta problemática. Se estudian tres díadas madre-hijo/a, con sintomatología depresiva materna y se desarrolla una intervención psicoterapéutica breve utilizando el modelo de Interacciones Guiadas. Los resultados muestran una reducción en la sintomatología depresiva y un aumento en sensibilidad materna, cooperatividad infantil y calidad vincular. La intervención realizada resulta eficaz en las variables estudiadas, requiriéndose nuevas aplicaciones en muestras de mayor tamaño para confirmar estos hallazgos.

  11. Fenologia, cultivo in vitro e aclimatização da bromélia ameaçada de extinção Nidularium minutum Mez

    Directory of Open Access Journals (Sweden)

    Flávia Maria Kazue Kurita

    2013-12-01

    Full Text Available http://dx.doi.org/10.5007/2175-7925.2014v27n1p59   O conhecimento da fenologia de uma espécie indica o período mais favorável à coleta de sementes maduras, que podem ser utilizadas na produção de mudas por meio de métodos eficientes como o cultivo in vitro. Essa técnica tem sido considerada uma estratégia para a propagação de espécies ameaçadas de extinção, como é o caso da bromélia Nidularium minutum Mez. Este artigo teve por objetivo identificar a época de frutificação e de produção de sementes de exemplares in situ de N. minutum e estabelecer um protocolo de cultivo in vitro a partir de sementes. A fenologia da espécie foi acompanhada por 12 meses em plantas na Estação Biológica do Alto da Serra, em Paranapiacaba-SP. Os resultados mostraram que o melhor período para a colheita das sementes foi de junho a agosto de 2008. O processo germinativo ocorreu em todas as temperaturas testadas, tendo sido mais eficiente aos 26ºC, não sendo necessários sais minerais. As melhores condições para o crescimento das plantas ocorreram com a mesma temperatura, em meio Murashige e Skoog (MS contendo metade da concentração dos macronutrientes. Por meio desse protocolo, é possível conservar as plantas in vitro e otimizar sua produção para o uso em programas de repovoamento.

  12. Annotated Ada 95 Reference Manual.

    Science.gov (United States)

    1994-12-21

    Character ’®; --Character’Val(174) Macron constant Character ’ --Character Val(175) --Character positions 176 (16#BO#).. 191 (16#BF#): 22 Degree-Sign...2.1(15) Macron A.3.3(21) MessagcProcedure 3.10(26) multiply operator 4.4(1), 4.5.5(1) Main 3.9.2(20), 3.10.2(22), 6.3.1(21), method multiplying

  13. JOVIAL/Ada Microprocessor Study.

    Science.gov (United States)

    1982-04-01

    and is approved for publication. APPROVED:Q-t A ,-* RICHARD M. MOTTO Project Engineer APPROVED: j J CINIAK, Colonel, US"F Chief, Comand and Control...system designers and embedded computer applications, it does not have a direct effect on software development. There are three expected developments which...constraints and characteristics of the target embedded computer system. Some alternatives and related comments are presented below: 1. Access variables

  14. ADA APA DENGAN KECEMASAN MATEMATIKA?

    Directory of Open Access Journals (Sweden)

    Fatrima Santri Syafri

    2017-01-01

    ABSTRACT Math anxiety is one of the factors that affect mathematics achievement. These factors can be influenced by several things, both with regard to internal factors and external factors learners. In this paper will discuss what it is about math anxiety, math anxiety indicators, impacts, and how to overcome them. Based on several studies of math anxiety, math anxiety appears that negatively affect the results of the teaching / learning achievement and influence to the mathematical abilities of learners. As a teacher or prospective teacher should also reduce math anxiety so as to reduce math anxiety owned by students. So that when giving instruction error does not occur in the delivery and may reduce students' mathematical anxiety. A teacher/tutors should understand how math anxiety indicator of students, so as to overcome math anxiety that occurs in students.at home. Keywords: math anxiety.

  15. Languages Beyond Ada and Lisp

    Science.gov (United States)

    1991-08-05

    believes everything Maggie says, but Mikhail disbelieves everything she says, so when each is asked whether the apparition in question is, or is not, the...these concepts during their talks today. We might want to go back and look at what they said. Littman. I still want to see examples. I’ll be a pain

  16. Mudanças organizacionais na adoção de tecnologias avançadas de manufatura Organizational changes in the adoption of advanced manufacturing technologies

    Directory of Open Access Journals (Sweden)

    Rafaela da Rosa Cardoso

    2010-12-01

    Full Text Available Para que a adoção de Tecnologia Avançada da Manufatura (AMT possa, de fato, proporcionar vantagens competitivas às empresas, faz-se necessário que essas tecnologias sejam selecionadas segundo critérios que considerem aspectos estratégicos. As características organizacionais de uma empresa influenciam sobremaneira o processo de adoção de AMT, de tal forma que se faz necessário desenvolver recomendações para a revisão do projeto organizacional. O presente trabalho propõe um processo para a geração de tais recomendações, através de uma metodologia denominada de "refinamentos sucessivos". Como resultado deste processo de "refinamentos sucessivos" obtém-se um conjunto de recomendações para a revisão do projeto organizacional, baseados em requisitos estabelecidos pelo processo de adoção de AMT. Essas recomendações constituem um conjunto de decisões a serem tomadas acerca do projeto organizacional para adequá-lo às demandas de uma nova tecnologia a ser introduzida, ou seja, a implementação de AMT.In order for the adoption of Advanced Manufacturing Technology (AMT to provide competitive advantages to the companies, it is necessary to select these technologies according to criteria that consider strategic aspects. The organizational characteristics of a company influence particularly the process of AMT adoption, in such a way that it is necessary to develop recommendations for the review of the organizational project. The present work proposes a process for the generation of these recommendations, which through a methodology called 'successive refinements' produces a set of recommendations for the review of the organizational project, based on requirements established by the AMT adoption process. These recommendations are a set of decisions that may be taken about the organizational project to adapt them to demands of the new technology to be introduced, in other words, the AMT implementation.

  17. Neoplasia avançada de esôfago: diagnóstico ainda muito tardio Advanced esophageal cancer: still a delayed diagnosis

    Directory of Open Access Journals (Sweden)

    Fernanda Prata Thuler

    2006-09-01

    Full Text Available RACIONAL: A neoplasia de esôfago está entre as 10 mais incidentes no Brasil. O diagnóstico é geralmente tardio e a sobrevida média é de 4 a 6 meses, independente da terapêutica. O alívio da disfagia e a melhora da qualidade de vida são os objetivos principais da terapêutica paliativa. OBJETIVO: Avaliar a qualidade de vida e a paliação da disfagia obtida com diferentes tipos de tratamento oferecidos aos pacientes com neoplasia avançada de esôfago. PACIENTES E MÉTODO: Avaliação prospectiva de 38 pacientes com neoplasia avançada de esôfago, com disfagia, sem possibilidade de tratamento curativo, entre setembro de 2001 a junho de 2005. Os pacientes foram alocados aleatoriamente, de acordo com a disponibilidade da terapia ou preferência do paciente ou do médico responsável, sendo 14 tratados com colocação de prótese (9 metálicas auto-expansíveis, 4 plásticas e 1 plástica auto-expansível, 4 com cirurgia paliativa, 8 com gastrostomia (7 cirúrgicas e 1 endoscópica e 12 com sonda nasoenteral. RESULTADOS: Houve melhora do índice médio de disfagia em 30 dias em todos os grupos, exceto no da gastrostomia. A colocação da prótese de esôfago melhorou a disfagia de forma estatisticamente significante em relação às outras terapias paliativas. A qualidade de vida avaliada pela mediana do índice de Karnofsky não apresentou melhora em nenhum grupo de pacientes. O número de internações necessárias não foi diferente entre os grupos. A duração média das internações foi maior no grupo de tratamento cirúrgico (42 dias, embora sem diferença significativa. Não houve diferença na sobrevida média dos pacientes, independente do tipo de tratamento. CONCLUSÃO: A paliação ideal para todos os casos não existe. O método deve ser individualizado para cada paciente. O tratamento cirúrgico paliativo é o mais oneroso, devido ao prolongado tempo médio de internação desses pacientes. Infelizmente, o diagnóstico de

  18. COMPORTAMENTO EM COMPRESSÃO DE ARGAMASSAS REFORÇADAS COM FIBRAS NATURAIS II. CURVA TENSÃO-DEFORMAÇÃO ANALÍTICA E RELAÇÃO CONSTITUTIVA DE COMPRESSÃO

    Directory of Open Access Journals (Sweden)

    Romildo Dias Toledo Filho

    Full Text Available RESUMO Esta é a segunda parte de um artigo dividido em duas partes que visa avaliar, analítica e experimentalmente, o comportamento em compressão de argamassas reforçadas com fibras naturais. No presente artigo são apresentadas relações analíticas para prever a completa curva tensão-deformação de argamassas reforçadas com fibras naturais, bem como propriedades-chave, tais como a resistência à compressão e o módulo de elasticidade, em função dos parâmetros de reforço das fibras e das propriedades da matriz. Uma relação constitutiva entre o módulo de elasticidade e a resistência a compressão é proposta para os compósitos reforçados com fibras naturais, com base na relação empírica proposta para o concreto simples. A precisão da expressão analítica usada para prever a completa curva tensão-deformação dos compósitos de argamassa reforçada com fibras naturais, foi verificada comparando-se curvas tensão-deformação experimentais com as previstas pelo modelo. Valores do módulo de elasticidade dos compósitos obtidos com base na relação constitutiva proposta foram comparados com os valores experimentais. Os resultados indicaram que tanto a expressão analítica quanto a lei constitutiva apresentaram boa correlação com os dados experimentais.

  19. Avaliação morfológica do oviduto e desempenho zootécnico de poedeiras comerciais (Gallus gallus) da linhagem Lohmann Selected Legorn submetidas e não submetidas a muda forçada.

    OpenAIRE

    Luciana Barbosa de Carvalho Borba

    2007-01-01

    Este trabalho teve o objetivo de avaliar a morfologia do oviduto (regiões do magno, istmo e glândula da casca) e desempenho zootécnico de poedeiras comerciais (Gallus gallus) submetidas e não submetidas a muda forçada. Para tanto foram utilizadas 4.000 poedeiras da linhagem Lohmann Selected Leghorn (LSL), com 65 semanas de idade alojadas em gaiolas de plástico e ferro, em uma granja comercial na cidade de Glória do Goitá, estado de Pernambuco. As poedeiras foram divididas em dois grupos, a...

  20. SCALA – Sistema de Comunicação Alternativa para Letramento de Pessoas com Autismo: implementação de um sistema de busca avançada

    OpenAIRE

    Franciscatto, Roberto; Perez, Cláudia Camerini Côrrea; Bez, Maria Rosângela; Passerino, Liliana Maria; Volpatto, Diego

    2016-01-01

    O trabalho em questão objetiva descrever sobre o processo de desenvolvimento de um sistema de busca avançada por pictogramas, através de palavras-chave e elementos de seleção para o sistema SCALAWEB. Ao longo do texto são abordados exemplos e conceituações de tecnologias assistivas de comunicação alternativa, uma síntese sobre o sistema SCALAWEB e seus objetivos, as tecnologias e ferramentas utilizadas na implementação do sistema avançado de busca proposta para o mesmo. Ainda, são especificad...

  1. Archive of Digital Boomer Seismic Reflection Data Collected During USGS Field Activity 02LCA02 in Lakes Ada, Crystal, Jennie, Mary, Rice, and Sylvan, Central Florida, July 2002

    Science.gov (United States)

    Harrison, Arnell S.; Dadisman, Shawn V.; Davis, Jeffrey B.; Wiese, Dana S.

    2008-01-01

    In July of 2002, the U.S. Geological Survey and St. Johns River Water Management District (SJRWMD) conducted geophysical surveys in Lakes Ada, Crystal, Jennie, Mary, Rice, and Sylvan, central Florida, as part of the USGS Lakes and Coastal Aquifers (LCA) study. This report serves as an archive of unprocessed digital boomer seismic reflection data, trackline maps, navigation files, Geographic Information System (GIS) files, and formal Federal Geographic Data Committee (FGDC) metadata. Filtered and gained (a relative increase in signal amplitude) digital images of the seismic profiles are also provided. Refer to the Acronyms page for expansions of acronyms and abbreviations used in this report. The archived trace data are in standard Society of Exploration Geophysicists (SEG) SEG-Y format (Barry and others, 1975) and may be downloaded and processed with commercial or public domain software such as Seismic Unix (SU). Example SU processing scripts and USGS software for viewing the SEG-Y files (Zihlman, 1992) are also provided. The USGS Florida Integrated Science Center (FISC) - St. Petersburg assigns a unique identifier to each cruise or field activity. For example, 02LCA02 tells us the data were collected in 2002 for the Lakes and Coastal Aquifers (LCA) study and the data were collected during the second field activity for that study in that calendar year. Refer to http://walrus.wr.usgs.gov/infobank/programs/html/definition/activity.html for a detailed description of the method used to assign the field activity ID. The boomer plate is an acoustic energy source that consists of capacitors charged to a high voltage and discharged through a transducer in the water. The transducer is towed on a sled floating on the water surface and when discharged emits a short acoustic pulse, or shot, which propagates through the water, sediment column, or rock beneath. The acoustic energy is reflected at density boundaries (such as the seafloor, sediment, or rock layers beneath the

  2. Morbidity and survival in advanced AIDS in Rio de Janeiro, Brazil Morbidade e sobrevida em AIDS avançada no Rio de Janeiro, Brasil

    Directory of Open Access Journals (Sweden)

    Ângela J. GADELHA

    2002-07-01

    Full Text Available Opportunistic diseases (OD are the most common cause of death in AIDS patients. To access the incidence of OD and survival in advanced immunodeficiency, we included 79 patients with AIDS treated at Hospital Evandro Chagas (FIOCRUZ from September 1997 to December 1999 with at least one CD4 count As doenças oportunistas (DO são a causa mais comum de morte em pacientes com AIDS. Para acessar a incidência de DO e a sobrevida na imunodeficiência avançada, foram incluídos 79 pacientes com AIDS tratados no Hospital Evandro Chagas (FIOCRUZ no período de Setembro de 1997 a Dezembro de 1999, com ao menos uma contagem de células CD4 <= 100/mm³. A incidência de DO foi analisada pela regressão de Poisson e a sobrevida pela analise de Kaplan Meier e Cox, considerando um período retrospectivo (anterior à contagem de CD4 <= 100 cels/mm³ e um prospectivo (após a contagem de CD4 <= 100 cels/mm³ e controlando-se características demográficas clínicas e laboratoriais. O intervalo de confiança estipulado foi o de 95%. O período médio de acompanhamento foi de 733 dias (IC = 683 - 782. Durante o estudo, nove (11,4% pacientes morreram. A sobrevida a partir do diagnóstico de AIDS foi em média de 2589 dias (IC = 2363 - 2816 e da data da contagem de CD4 <= 100 cels/mm³ foi em média de 1376 dias (IC = 1181 - 1572. A incidência de DO foi de 0,51 pp/ano no período pré-CD4 <= 100 cels/mm³ e 0,29 pp/ano no período pós-CD4 <= 100 cels/mm³. Um menor número de DO acumuladas no período pré-CD4 <= 100 cels/mm³ foi associado com taxas de incidência menores no período pós-CD4 <= 100 cels/mm³.O diagnóstico de AIDS baseado em contagem de CD4+ <= 200 cels/mm³ foi associado com menores taxas de incidência durante o período pós-CD4 <= 100 cels/mm³. As contagens basais de células CD4 acima de 50 cel/mm³ (HR = 0,16 foram associadas a um menor risco de morte assim como a restauração da contagem basal acima de 100 cels/mm³ (HR = 0

  3. Comparative In Vitro Binding Studies of TiCl2(dpme2, Ti(ada2(bzac2, and TiCl2(bzac(bpme Titanium Complexes with Calf-Thymus DNA

    Directory of Open Access Journals (Sweden)

    Pamita Awasthi

    2015-01-01

    Full Text Available The binding of TiCl2(dpme2 (1, (dpme = 6,6′-dimethyl-2,2′-bipyridine, Ti(ada2(bzac2 (2, (ada = adamantylamine; bzac = benzoylacetone, and TiCl2(bzac(bpme (3, (bpme = 4,4′-dimethyl-2,2′-bipyrdine with calf thymus (ct DNA has been studied by UV-visible spectroscopy, thermal denaturation, and circular dichroism spectroscopy. In UV-visible study complexes 1, 2, and 3 showed red, blue, and red shifts, respectively, upon the addition of ct-DNA along with a significant hyperchromism. The intrinsic binding constants (Kb calculated from UV-visible absorption studies were 2.3 × 103 M−1, 3.3 × 103 M−1 and, 7.1 × 103 M−1 for complexes 1, 2, and 3, respectively. The change in melting temperature (ΔTm was calculated to be 2-3°C for each complex. Circular dichroism (CD study showed blue shift for complex 2 and red shift for complexes 1 and 3 along with rise in molecular ellipticity upon the addition of complexes. Results suggest a binding mode of complex 2 different than 1 and 3.

  4. [Detection of entomopathogen nematode [EPN - sand flies (Phlebotomus tobbi)] caught in the wild in Aydın, Kuşadası town and its assessment as a biological control agent].

    Science.gov (United States)

    Karakuş, Mehmet; Arserim, Suha K; Töz, Seray Özensoy; Özbel, Yusuf

    2013-01-01

    In this study, the midgut of the sand flies investigated with direct method for the presence of parasites and other organisms. Wild sand flies collected in Kuşadası Town-Aydın, were dissected and midgut contents were examined by light microscopy. After midgut dissection, the head and genitalia of sand fly specimens were clarified and mounted for species identification. During the study, a total of 1027 sand flies were dissected. Eight and two species belonging to Phlebotomus and Sergentomyia genera were determined, respectively. Phlebotomus tobbi was found to be most abundant species (61.34%). A third stage of infective Entomopathogen Nematode belonging to Steinernematidae family was observed in the hemocoel of one specimen of P. tobbi during the dissection process. This is the first finding related to entomopathogen nematodes found in sand flies in Turkey. In the study, the sand fly fauna was determined in Kuşadası Town. For the control of sand flies, entomopathogenic nematodes which are not harmful for non-target organisms, can be used instead of chemical insecticides that can cause unknown damage in the environment.

  5. El espíritu del lugar en las Cañadas Reales de la Corona de Castilla./The spirit of the place in Canadas Royal Crown of Castile.

    Directory of Open Access Journals (Sweden)

    Cahn, Alicia Leonor

    2008-12-01

    Full Text Available El sistema de las Cañadas Reales y sus vías accesorias constituye un conjunto dinámico de gran trascendencia económica e histórica ─con 600 años de historia─ en el que se vinculan entre sí, dentro de un proceso productivo hábilmente organizado y dirigido a una finalidad concreta de índole comercial, los trazados viales de diferentes épocas, cada uno con sus testimonios particulares en cuanto a modos de hacer, tecnologías y materiales, en un amplio territorio interior./The Cañadas Reales system and accessory pathways is a dynamic set of great importance to economic and historical ─ 600 years of history ─ in which they are linked together within a production process skillfully organized and led for a particular purpose in nature commercial road paths from different eras, each with its particular testimony as to ways of doing things, technologies and materials in a wide hinterland.

  6. Secagem de fatias de abóboras (Cucurbita moschata, L. por convecção natural e forçada Drying of pumpkin (Cucurbita moschata, L. slices by natural and forced convection

    Directory of Open Access Journals (Sweden)

    Soraia Vilela Borges

    2008-12-01

    Full Text Available A abóbora (Cucurbita moschata, L. é uma importante fonte de provitamina A, de baixo custo, e sob a forma desidratada oferece diferentes opções de utilização e consumo. Secagens por convecção natural e forçada foram comparadas quanto ao grau de secagem atingido e encolhimento, em função da temperatura, velocidade de ar e dimensões do produto. Os resultados obtidos mostraram que o uso de fatias com volume de 6,25 cm³ em secador por convecção forçada a 50 °C e à velocidade de 5,5 x 10-4 ms-1 resultaram em produtos de menor encolhimento, sendo recomendadas estas condições.Besides its low price, Pumpkin (Cucurbita moschata, L. is an important source of provitamin-A, and when dehydrated it offers different options of utilizations and consumption. Natural and forced convection drying were compared according to the drying degree shrinkage as a function of temperature, and air velocity and product dimensions. The obtained results showed that slices with the volume of 6.25 cm³ in forced convection oven at 50 °C and at the velocity of 5.5 x 10-4 ms-1 resulted in a lower shrinkage products, so these conditions were recommended.

  7. Solução analítica para previsão do comportamento de vigas de concreto armado reforçadas com laminados de PRF

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    M. R. Garcez

    Full Text Available Visando desenvolver uma solução analítica para prever o comportamento de vigas de concreto armado reforçadas com laminados de PRF, com ou sem protensão, uma solução não-linear foi proposta, assumindo um diagrama momento-curvatura com resposta tri-linear. Os pontos característicos adotados para definir os estágios do diagrama foram: a fissuração do concreto, o escoamento do aço e capacidade última do elemento reforçado. As deflexões foram obtidas pela dupla integração do diagrama momento-curvatura da seção transversal do elemento reforçado, sendo geradas as respostas carga-deslocamento. A solução analítica foi implementada usando o software Matlab® e os resultados gerados se mostraram compatíveis aos obtidos experimentalmente, em ensaios de flexão de vigas de concreto armado reforçadas com laminados de PRF protendidos e não-protendidos.

  8. Solid waste recovery and insert your input as in industry: case study on the das Calçadas Street, the Recife commercial area | Recuperação de resíduos sólidos e inserção de sua entrada como na indústria: estudo de caso na rua das Calçadas, área comercial de Recife

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    Thaís Póvoas Souto

    2016-06-01

    Full Text Available The article deals with the problems of solid waste generated by the Das Calçadas Street  in Recife, bustling street commercials. Solid waste every day are becoming an increasing problem a real environmental chaos. Recycling is environmentally and economically most appropriate to deal with the solid waste of the commercial areas of all kinds. The problems generated by solid waste need to be made in a sustainable and socially inclusive. The introduction of collectors in the product lifecycle acting as selective collection tool and recycling brings great benefits for collectors and their associations for the waste generators and the environment. The National Solid Waste Policy is the instrument that enables all product lifecycle agents assume their responsibilities within the production process, in addition to fulfilling its social role inclusion of collectors, their associations and cooperatives. In the region of Das Calçadas Street to City Hall collection by EMLURB about 11 tons per day of waste the amount would be much higher if there was action of scavengers. Awareness and public policy actions are needed to optimize recycling and disposal for collection, application of the polluter pays principle is a necessity, as a way to force the companies to implement collection processes and selection of waste.

  9. Produtos da glicação avançada dietéticos e as complicações crônicas do diabetes Dietetics advanced glycation end-products and chronic complications of diabetes

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    Júnia Helena Porto Barbosa

    2009-02-01

    Full Text Available A geração dos produtos de glicação avançada é um dos principais mecanismos desencadeadores das doenças associadas ao diabetes mellitus, que incluem cardiopatia, retinopatia, neuropatia e nefropatia. Esta revisão tem como objetivo analisar o papel dos produtos de glicação avançada presentes na alimentação como mediadores das complicações diabéticas e apresentar estratégias de redução de sua ingestão. Para tanto, foram realizados levantamentos em bancos de dados de publicações da área, dos últimos 15 anos, considerando-se artigos de revisão, estudos clínicos e experimentais. Os produtos de glicação avançada são um grupo heterogêneo de moléculas formadas a partir de reações não enzimáticas entre grupamentos amino e carbonilo, sendo a carboximetilisina e a pentosidina exemplos de produtos de glicação avançada identificados em alimentos e in vivo. Os produtos de glicação avançada ingeridos são absorvidos, somando-se aos endógenos no surgimento e na progressão das diversas complicações do diabetes, existindo uma correlação direta entre o consumo e a concentração sanguínea. Sua restrição na alimentação se correlaciona à supressão dos níveis séricos de marcadores de doença vascular e de mediadores inflamatórios diretamente envolvidos no desenvolvimento das degenerações diabéticas. As atuais orientações dietéticas centram-se na proporção em nutrientes e na restrição energética, sem considerar o risco da ingestão de produtos de glicação avançada formados durante o processamento dos alimentos. Recomendações simples, como a utilização de temperaturas baixas por períodos mais curtos, em presença de água, no preparo de alimentos, exercem efeitos importantes na prevenção das complicações do diabetes. O estudo dos mecanismos envolvidos na geração de produtos de glicação avançada e das propriedades anti-glicação de compostos presentes nos alimentos podem contribuir com

  10. Variação Temporal no Prognóstico e Tratamento da Insuficiência Cardíaca Avançada - Antes e Após 2000

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    Carlos Henrique Del Carlo

    2014-06-01

    Full Text Available Fundamento: O tratamento da insuficiência cardíaca evoluiu nas últimas décadas, sugerindo que sua sobrevida tem aumentado. Objetivo: Verificar se houve melhora na sobrevida dos pacientes com insuficiência cardíaca avançada. Métodos: Comparamos retrospectivamente os dados de seguimento e tratamento de duas coortes de pacientes com insuficiência cardíaca sistólica admitidos para compensação até o ano 2000 (n = 353 e após 2000 (n = 279. Foram analisados: morte hospitalar, re-hospitalizações e morte no seguimento de 1 ano. Utilizamos os testes U de Mann-Whitney e qui-quadrado para comparação entre os grupos. Os preditores de mortalidade foram identificados pela análise de regressão por meio do método dos riscos proporcionais de Cox e análise de sobrevida pelo método de Kaplan-Meier. Resultados: Os pacientes internados até o ano 2000 eram mais jovens, tinham menor comprometimento ventricular esquerdo e receberam menor proporção de betabloqueadores na alta. A sobrevida dos pacientes hospitalizados antes de 2000 foi menor do que a dos hospitalizados após 2000 (40,1% vs. 67,4%; p < 0,001. Os preditores independentes de mortalidade na análise de regressão foram: a etiologia chagásica (hazard ratio: 1,9; intervalo de confiança de 95%: 1,3-3,0, inibidores da enzima conversora da angiotensina (hazard ratio: 0,6; intervalo de confiança de 95%: 0,4-0,9, betabloqueador (hazard ratio: 0,3; intervalo de confiança de 95%: 0,2-0,5, creatinina ≥ 1,4 mg/dL (hazard ratio: 2,0; intervalo de confiança de 95%: 1,3-3,0, sódio sérico ≤ 135 mEq/L (hazard ratio: 1,8; intervalo de confiança de 95%: 1,2-2,7. Conclusões: Pacientes com insuficiência cardíaca avançada apresentaram melhora significativa na sobrevida e redução nas re-hospitalizações. O bloqueio neuro-hormonal, com inibidores da enzima conversora da angiotensina e betabloqueadores, teve papel importante no aumento da sobrevida desses pacientes com insufici

  11. A experiência em extensão no pet matemática da UFSC e as olimpíadas de matemáticaDOI:10.5007/1807-0221.2010v7nespp18

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    José Luiz Rosas Pinho

    2010-11-01

    Full Text Available Neste trabalho relatamos a nossa experiência de treze anos em projetos de extensão na tutoria do programa PET do Curso de Matemática da UFSC. Quatro projetos de maior relevância são aqui brevemente apresentados, além de dois outros, atualmente considerados como Projetos Institucionais Permanentes da UFSC. Esses dois projetos são a Olimpíada Regional de Matemática de Santa Catarina (ORM e a Revista da ORM, que são aqui descritos com mais detalhes. Em especial, discutimos os aspectos criativos necessários à resolução dos problemas olímpicos de matemática e ressaltamos a importância do desenvolvimento do raciocínio crítico na formação de nossos estudantes do ensino básico.

  12. Anemia nos pacientes com insuficiência cardíaca avançada Anemia en los pacientes con insuficiencia cardíaca avanzada Anemia in patients with advanced heart failure

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    Juliano Cardoso

    2010-10-01

    Full Text Available FUNDAMENTO: Anemia está associada à pior evolução nos pacientes com insuficiência cardíaca (IC. Entretanto, há poucos estudos sobre a anemia nos pacientes com IC avançada. OBJETIVO: Avaliar as características da anemia na IC em fase avançada. MÉTODOS: Foram incluídos 99 pacientes hospitalizados para compensação de IC (CF IV/NYHA, com idade > 18 anos e FEVE 12 g/dl. A anemia foi marcador independente de mau prognóstico na análise multivariada (mortalidade 47% vs 24,6%, p = 0,016, risco relativo 2,54. CONCLUSÃO: Anemia acomete, aproximadamente, 1/3 dos pacientes com IC avançada, e a deficiência de ferro é uma importante etiologia. Pacientes anêmicos são mais idosos e apresentaram função renal mais deteriorada. A melhora da congestão não foi suficiente para melhorar a anemia na maioria dos casos. Nos pacientes com IC avançada, a anemia é marcador independente de mau prognóstico.FUNDAMENTO: Anemia está asociada a peor evolución en los pacientes con insuficiencia cardíaca (IC. Mientras tanto, hay pocos estudios sobre la anemia en los pacientes con IC avanzada. OBJETIVO: Evaluar las características de la anemia en la IC en fase avanzada. MÉTODOS: Fueron incluidos 99 pacientes hospitalizados para compensación de IC (CF IV/NYHA, con edad > 18 años y FEVI 12 g/dl. La anemia fue marcador independiente de mal pronóstico en el análisis multivariado (mortalidad 47% vs 24,6%, p = 0,016, riesgo relativo 2,54. CONCLUSIÓN: Anemia afecta, aproximadamente, 1/3 de los pacientes con IC avanzada, y la deficiencia de hierro es una importante etiología. Pacientes anémicos son más añosos y presentaron función renal más deteriorada. La mejora de la congestión no fue suficiente para mejorar la anemia en la mayoría de los casos. En los pacientes con IC avanzada, la anemia es marcador independiente de mal pronóstico.BACKGROUND: Anemia is linked with worsening of progress in patients with heart failure (HF. However, there are

  13. «Bajo el casco de Hades»: menores migrantes no acompañadas como posibles víctimas de trata y su triple invisibilización

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    María J. García de Diego

    2013-12-01

    Full Text Available El presente texto pretende acercarse al caso de las menores migrantes no acompañadas, con el fin de visibilizar las peculiaridades de su proyecto migratorio y el contexto en el que viven en España. Este artículo considera transversal la perspectivade género y recoge las incidencias de trata de seres humanos y explotaciónde estas menores migrantes.Desde comienzos de siglo ha aumentado el número de las menores que llegan a nuestro país. A las dificultades, ya conocidas, que enfrentan los menores no acompañados, se añaden otras que las chicas sufren en virtud de su género. Estas menores son, en ocasiones,víctimas de redes de explotación sexual, laboral o, tristemente ambas

  14. Estudo da germinação e crescimento in vitro de Hadrolaelia tenebrosa (Rolfe) Chiron & V.P. Castro (Orchidaceae), uma espécie da flora brasileira ameaçada de extinção

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    Suzuki,Rogério Mamoru; Moreira,Vania Carolina; Nakabashi,Myna; Ferreira,Wagner de Melo

    2009-01-01

    As orquídeas são espécies seriamente ameaçadas de extinção. Por isso, estudos sobre a propagação e desenvolvimento dessas plantas são extremamente importantes. Assim, este trabalho procurou estudar a influência do meio de cultura na germinação in vitro de sementes de Hadrolaelia tenebrosa, no desenvolvimento inicial dos protocormos até a formação das plântulas, bem como no crescimento dessas durante o primeiro ano de cultivo in vitro. Os resultados demonstraram que o método ideal para a multi...

  15. Caracterización del nivel de información sobre ITS/VIH/sida en adolescentes de la escuela secundaria básica "José Luis Arruñada" Characterization of the information level on sexual transmission infection (STI/HIV/aids in adolescents of the "José Luis Arruñada" basic secondary school

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    Alejandro Fadragas Fernández

    2012-03-01

    Full Text Available Introducción: en Cuba, el Programa Nacional de Prevención y Control de las Infecciones de Transmisión Sexual y el VIH/sida, se inició desde 1986, con el objetivo fundamental de evitar que el proceso de la infección-enfermedad, se convirtiera en un importante problema de salud para la población cubana. Objetivo: caracterizar el nivel de información que sobre las ITS/VIH/sida, tienen los adolescentes que pertenecen a la escuela secundaria básica "José Luis Arruñada", correspondiente al municipio Plaza de la Revolución, en el año 2009. Métodos: se realizó un estudio observacional descriptivo de corte transversal, en un grupo de adolescentes. De un universo de 180 de ellos, se aplicó el estudio a una muestra constituida por 121 participantes, para saber el nivel de información que tenían sobre las enfermedades estudiadas, mediante la aplicación de un cuestionario. Resultados: tenían nociones sobre las infecciones de transmisión sexual, 115 adolescentes para un 95,04 %, las fuentes de obtención de la información más reconocidas fueron la familia en 112 para un 92,56 %, y la escuela en 75 para un 61,98 %. Las infecciones de transmisión sexual más identificadas por ellos fueron: el VIH/sida 116 para un 95,86 %, la gonorrea 108 para un 89,25 % y la sífilis 101, para un 83,47 %; fueron menos reconocidas la gardella vaginal 4, chancro blando 11, clamidiasis 13, moniliasis 19 y la trichomoniasis 26 para un 3,30 %, 9,09 %, 10,74 %, 15,70 % y un 21,48 % respectivamente. De los adolescentes encuestados, 51 consideró que las posibilidades de contagio de las infecciones de transmisión sexual, son grandes en el sexo oral para un 42,14 %, 119 encuestados refirieron tener nociones sobre sexo seguro para un 98,34 %, y dentro de las variantes se identificó el uso del condón. Conclusiones: los adolescentes tenían un adecuado nivel de información sobre algunas de las enfermedades estudiadas.Introduction: in Cuba, the National Program

  16. Considerações sobre a propagação e o uso ornamental de plantas raras ou ameaçadas de extinção no Rio Grande do Sul, Brasil.

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    Cecília Maciel Barroso

    2007-06-01

    Full Text Available A extração de plantas silvestres para a comercialização, além de ser atividade ilegal e não sustentada, é considerada uma das principais causas de sua extinção. A introdução de plantas exóticas é considerada a segunda maior ameaça à conservação da biodiversidade mundial. Esta se voltou para o comércio de plantas ornamentais nos últimos tempos, e deu ocasião a invasões de muitas dessas plantas. A utilização de plantas nativas para ornamentação diminui consideravelmente os riscos de contaminação biológica quando estas escapam das áreas de cultivo. Sua propagação em viveiros legalizados diminui a pressão por coletas na natureza. Porém, quanto ao uso de plantas raras ou ameaçadas de extinção na ornamentação, questões como a pressão de coleta, a variabilidade genética intra e interespecífica e a seleção de variedades devem ser consideradas. Este artigo aborda estas e outras questões, como o conceito de espécie nativa, a propagação de espécies ameaçadas de extinção e a proliferação de determinadas variedades em detrimento de outras, que são pertinentes àqueles que desejam promover o uso de plantas nativas na ornamentação e no paisagismo.

  17. Geochemical study of two obsidian production centers in the Prehistory of Tenerife: El Tabonal de los Guanches (Icod de los Vinos and el Tabonal Negro (Las Cañadas

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    Hernández Gómez, Cristo M.

    2008-12-01

    Full Text Available The obsidian production is one of the work processes that allow a good characterization of the Guanches, first inhabitants of Tenerife (Canary Islands. On this occasion, addresses the geochemical study of the volcanic flows where the main obsidian sources of the Aboriginal of Tenerife are located: The Tabonal de Los Guanches (Icod de Los Vinos and the Tabonal Negro, Mña. Blanca (Las Cañadas del Teide characterized as Production Centres. The aim is to establish the compositional differences between the two in order to trace the distribution of their lithic productions in the island territory and recognize the pattern of supply that was put into practice.

    La producción obsidiánica es uno de los procesos de trabajo que mejor permite la caracterización social de los guanches, primeros habitantes de Tenerife (Canarias. En esta ocasión se aborda el estudio geoquímico de las coladas en las que se ubican sus principales fuentes de aprovisionamiento de obsidiana: El Tabonal de Los Guanches (Icod de los Vinos y El Tabonal Negro en Mña. Blanca (Las Cañadas del Teide, consideradas desde el punto de vista arqueológico como Centros de Producción. El objetivo es establecer las diferencias composicionales entre ambas para poder rastrear la distribución de sus respectivas producciones líticas en el territorio insular y reconocer el modelo de suministro que se puso en práctica.

  18. Análise dialélica parcial em gerações avançadas para seleção de populações segregantes de trigo

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    Adérico Júnior Badaró Pimentel

    2013-12-01

    Full Text Available O objetivo deste trabalho foi estimar, em gerações avançadas, os efeitos da capacidade geral e específica de combinação de genitores de trigo, bem como selecionar populações segregantes superiores. Doze genitores e suas 36 populações nas gerações F2 e F3, obtidas em arranjo de dialelo parcial, foram avaliados quanto à produtividade de grãos. Utilizou-se o delineamento em látice 7x7, com duas repetições, mais um tratamento para completar o látice. O efeito de capacidade geral de combinação foi significativo, nas duas gerações. Observou-se alta correlação (0,83 dos efeitos de capacidade geral de combinação entre gerações, mas inexpressiva influência dos efeitos de gerações e de anos na classificação dos cruzamentos. As populações provenientes do cruzamento entre os genitores BRS 254, BRS 264 e IAC 364 (Tucuruí III e os genitores MGS 1 Aliança, VI 98053 e UFVT 1 Pioneiro apresentam maior potencial para obtenção de linhagens superiores, quanto à produtividade de grãos. O uso da análise dialélica parcial em gerações avançadas é promissor para programas de melhoramento de trigo por hibridação.

  19. Uso de nanopartículas no rastreamento de células em terapias avançadas: possibilidades e desafios para a aplicação clínica

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    . Jasmin

    2018-02-01

    Full Text Available Introdução: Para uma regulamentação específica e implementação das novas tecnologias avançadas na clínica médica, é preciso refinar o conhecimento sobre as células utilizadas. Um dos maiores desafios está na dificuldade em determinar os mecanismos de funcionamento das células após a terapia. Objetivo: Compreender, usando os métodos de rastreamento celular em pacientes, a distribuição e a função de células usadas em terapias avançadas. Método: Este trabalho foi elaborado pelo levantamento de artigos científicos nas bases de dados internacionais e da legislação vigente sobre a utilização clínica das nanopartículas. Resultados: Constatamos que a nanotecnologia já é uma ferramenta de grande utilidade, pois diversas nanopartículas magnéticas já são aprovadas para uso clínico; elas podem ser incorporadas por células e visualizadas por imagens de ressonância magnética. O presente texto discute as perspectivas sobre uso de nanomedicamentos para rastreamento celular na clínica médica. Conclusões: A utilização das nanopartículas necessita a elaboração e aprovação de leis, guias e normas que orientem a indústria, como outros setores, sobre a caracterização dos nanomateriais e potenciais riscos à saúde humana, animal e ao meio ambiente.

  20. Vigas de concreto reforçadas com bambu Dendrocalamus giganteus. II: modelagem e critérios de dimensionamento Concrete beams reinforced with Dendrocalamus giganteus bamboo. II: modeling and design criterions

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    Humberto C. Lima Júnior

    2005-12-01

    Full Text Available Este trabalho corresponde à segunda parte de uma publicação sobre o comportamento estrutural de vigas de concreto reforçadas com bambu, na qual se apresenta e discute a modelagem dessas estruturas para, em seguida, serem apresentadas sugestões e hipóteses para o dimensionamento desses elementos estruturais. Para tanto, utilizou-se um modelo computacional baseado no Método dos Elementos Finitos, ao qual foram incorporadas sub-rotinas com as leis constitutivas do bambu e do concreto. Para calibração do modelo lançou-se mão dos dados experimentais de oito vigas de concreto reforçadas com bambu. Os resultados obtidos com o modelo computacional foram comparados com os experimentais, observando-se grande concordância. Finalmente, sugerem-se critérios de dimensionamento, os quais foram aplicados em um exemplo prático.This paper corresponds to the second part of a publication concerning the structural behaviour of concrete beams reinforced with bamboo. Modelling of concrete beams reinforced with bamboo-splint are presented and discussed. In addition, some design suggestions and hypotheses are presented. To perform the study, a Finite Element Program was used and some procedures were programmed and linked to it. The program was calibrated with the experimental data of eight concrete beams reinforced with bamboo-splint, whose results presented great accuracy. Finally, some design procedures were suggested and a practical example is given.

  1. Osmanlı İdaresinde Kıbrıs Adasında Faaliyet Gösteren Konsoloslar ve Faaliyetleri (1571-1878 The Consuls And Their Activities In Cyprus Under The Ottoman Administration (1571-1878

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    Ali Efdal ÖZKUL

    2013-03-01

    on consulate activities in Cyprus during theOttoman period including consuls, their interpreters, and the tradecarried out by the traders and their trading products.This study has been supported by the data gained from CyprusNicosia judicial record (Şer-i Sicil registers and from the diary entries of the consuls, vice-consuls of the other countries and those of Europeantravellers.The findings of the study aims to demonstrate and reachconclusions on the importance of Cyprus in terms of trade in theMediterranean Sea, the influence of such trade on Cypriot citizens, thepositive effects and negative effects of the consuls and their interpreterson the socio-economic structure in Cyprus. Kıbrıs, Akdeniz’de ve özellikle Doğu Akdeniz’de stratejik ve coğrafibakımdan çok önemli bir konuma sahip bulunmaktaydı. Söz konusukonumundan dolayı tarih boyunca Akdeniz ticaretinde önemli bir payasahip olmuştur. Tarih boyunca Akdeniz’de ticaret yapan devletler Kıbrısadasını da çeşitli amaçları için kullanmaktaydılar. Dolayısıyla Osmanlıülkesinde ticaret yapan devletlerin hemen hemen hepsinin adadatüccarları bulunmaktaydı. Kıbrıs adasında bulunan yabancı tüccarlarınsorunlarıyla ilgilenmeleri için İstanbul’da elçileri bulunan devletleradaya vekilleri olan konsolosları atamaktaydılar. Söz konusukonsoloslara ticareti canlandırmak için Osmanlı Devleti tarafındangeniş yetkiler verilmiştir. Başlangıçta Osmanlı Devleti konsoloslarınKıbrıs adasında sadece Tuzla kazasında kalmalarına izin vermişti.Ancak 18. yüzyılın sonları ile 19. yüzyılda adada konsolosları olandevletlerin Limasol’da, Mağusa’da, Baf’ta ve hatta Lefkoşa’da konsolosvekilleri olmaya başlamıştı.Kıbrıs adasının ticaretinde söz sahibi ülkelerin başında daİngiltere, Fransa ile Hollanda ve onun adadaki temsilcisi olan konsolosuve konsolos tercümanı gelmekteydi. Osmanlı idaresinde adada görevyapan konsoloslar ve terc

  2. Avaliação sensorial de bebidas de goiaba adoçadas com diferentes agentes adoçantes Sensory evaluation of guava drinks sweetened with different sweetening agents

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    Aline Gurgel Fernandes

    2009-06-01

    Full Text Available Devido à crescente procura por bebidas à base de frutas tropicais e à expansão do segmento de produtos com valores calóricos reduzidos, este trabalho objetivou avaliar o grau de doçura, sabor, impressão global e a intenção de compra das bebidas de goiaba adoçadas com diferentes agentes adoçantes através de frequência de notas, teste de médias e Mapa de Preferência Interno (MPI. Utilizaram-se polpa de goiaba, água potável e diferentes agentes adoçantes (sacarose, mistura ciclamato/sacarina, aspartame, acesulfame-K, estévia e mistura sacarina/ciclamato sódico/acesulfame-K. A avaliação sensorial foi realizada com 100 provadores não treinados em teste laboratorial através do delineamento de blocos completos balanceados. Objetivando a avaliação das respostas individuais de cada provador, as respostas sensoriais foram avaliadas pela metodologia do MPI, empregando-se a técnica de Análise de Componentes Principais. As bebidas de goiaba adoçadas com sacarose e aspartame apresentaram avaliação sensorial semelhante por parte dos consumidores, apresentando os maiores valores médios no teste de aceitação, enquanto as adoçadas com estévia, com a mistura de três agentes adoçantes e a mistura ciclamato/sacarina apresentaram os valores mais baixos na avaliação sensorial. A utilização do MPI confirmou os resultados obtidos através de frequência de notas e teste de médias.Due to a constant search for tropical fruit drinks and calorie reduced products, this work aimed to evaluate the degree of sweetness, flavor, overall global impression, and purchase intention of guava drinks sweetened with different sweetening agents through the response rank frequency and average test, and internal preference mapping (IPM. Guava pulp, drinking water, and sweetening agents (sucrose, mixture cyclamate/saccharine, aspartame, acesulfame K, stevia and mixture saccharine/sodium cyclamate/acesulfame K were used. The sensory evaluation was

  3. PRODUCTIVE AND EGG QUALITY TRAITS OF LAYING QUAIL SUBMITTED TO FORCED MOLTING ASPECTOS PRODUTIVOS E QUALIDADE DE OVOS DE CODORNAS JAPONESAS SUBMETIDAS A DIFERENTES MÉTODOS DE MUDA FORÇADA

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    Claúdio Cabral Campello

    2009-09-01

    Full Text Available This work was performed to verify egg production of Japanese quails submitted to induced molt by zinc oxide method (MZ and fasting (MC. A total number of 160 Japanese quails with 48 weeks of age were evaluated for post-molt egg production, percentage of egg contents and the viability rate of eggs for 12 weeks. According to the applied methods (fasting or zinc oxide, the birds were submitted to different body weight losses (BWL: 25 or 35%. The quails were separated into different treatment groups, according to their body weight loss during molt: Control group (unmolted quails, MC (induced by MC with 35% of BWL; MZ25 (induced by MZ with 25% of BWL; MZ35 (induced by MZ with 35% of BWL. Each treatment has 8 replicates with five birds each. The quails were evaluated for egg-laying production, egg weight, yolk and shell weight and their ratio. Between the second and fourth weeks of egg laying production, the MZ25 group had the best egg laying performance. There wasn’t significant improvements for egg characteristics and feed conversion of molted quails compared to the ones of control group. The forced molt by zinc oxide was able just to improve, numerically, egg production during the first weeks when the quails were submitted to a 25% body weight loss.

    KEY WORDS: Coturnix japonica, eggs, fasting, forced molting, quail, zinc oxide.

    O objetivo deste trabalho foi o de observar o desempenho produtivo obtido por codornas induzidas à muda pelo método alternativo do óxido de zinco (MZ e método convencional ou do jejum (MC. Foram utilizadas 160 codornas japonesas, com 48 semanas de idade, para avaliação do desempenho, do percentual dos constituintes dos ovos, bem como da taxa de ovos viáveis, durante doze semanas. De acordo com o método utilizado, a fome forçada ou a anorexia parcial provocou perda de peso corporal (PPC nas aves, sendo formados os seguintes grupos: Controle (codornas não tratadas; MC (indução pelo MC com

  4. Morfometria do oviduto de poedeiras comerciais semipesadas submetidas a diferentes métodos de muda forçada Morphometry of the oviduct of the brown egg layer hens submitted different methods of molt induction

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    Cristiane Soares da Silva Araújo

    2007-02-01

    Full Text Available Este experimento foi conduzido com o objetivo de avaliar a morfometria do oviduto de poedeiras submetidas a diferentes métodos de indução de muda forçada. Duzentas e oito aves com 58 semanas de idade foram distribuídas em um delineamento inteiramente casualizado, com quatro tratamentos (método Califórnia, dieta com alto teor de zinco, dieta com baixo cálcio e com baixo sódio e quatro repetições de 12 aves cada. Avaliou-se a biometria do oviduto no início do experimento, no 28°. dia e em três períodos subseqüentes à realização da muda forçada, analisando-se o peso corporal da ave, a percentagem do oviduto e do ovário, o número de pregas do magno e do istmo e o comprimento das diferentes partes que compõem o oviduto. No período pós-muda, as características macroscópicas do oviduto não sofreram influência dos tratamentos estudados.This experiment was aimed at evaluating the performance, oviduct morphometric, hormone concentration and bone density in laying hens submitted of the different methods of molt induction. Two hundred-eight laying hens, 58 weeks of age, were randomly divided into four treatments groups (california method, diet of high-zinc, diet of low-calcium and diet of low-sodium and four replicates. The experiment evaluated biometrics characteristics on day 1, 28 of the experiment and in three periods postmolt: body weight, ovary percentage, oviduct percentage, number of folds of the magnum and isthmus, and length of the different parts of oviduct. In the postmolt period, the morphometric analysis of the birds were not affected by any of the experimental treatments.

  5. Expansão maxilar em adultos e adolescentes com maturação esquelética avançada Maxillary expansion in adults and adolescents with advanced skeletal maturation

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    Rowdley Robert Pereira Rossi

    2009-10-01

    Full Text Available A deficiência transversa da maxila é um fator agravante e complicador do tratamento ortodôntico em adultos. Sua correção ainda gera dúvidas e controvérsias entre clínicos e pesquisadores. O objetivo deste trabalho foi analisar e discutir fatores determinantes para o planejamento da expansão maxilar em adultos e adolescentes com maturação esquelética avançada. Ausências dentárias múltiplas, grandes inclinações dentoalveolares para vestibular, recessão gengival, perda óssea alveolar e mobilidade dos dentes posterossuperiores contraindicam a realização de expansão rápida da maxila em indivíduos adultos ou com maturação esquelética avançada. No entanto, esses fatores não devem ser considerados isoladamente para a escolha do método de expansão palatal nesses pacientes. Nessas situações, a Expansão Rápida da Maxila Assistida Cirurgicamente (ERMAC pode ser uma opção, entretanto, a escolha por essa técnica deve basear-se principalmente na idade do paciente, no grau de maturação esquelética, na localização da deficiência transversa da maxila e nas estruturas anatômicas que oferecem maior resistência à expansão maxilar. O Hyrax é o aparelho mais indicado para indivíduos que vão se submeter à ERMAC.The transverse maxillary deficiency is a complication factor in adults' orthodontic treatment. Its correction still generates doubts and controversies between clinicians and researchers. The aim of this paper is to discuss the determinative factors in planning maxillary expansion in adults and adolescents with advanced skeletal maturation. Multiple dental absences, several dentoalveolar buccal inclination, gingival recession, alveolar bone loss and mobility of posterosuperior teeth contraindicate the rapid maxillary expansion in adults or patients with advanced skeletal maturation. However, these factors should not be considered separately when choosing the method for palatal expansion in adults. In these

  6. Una ruina habitada desde el presente: vestigios del horror, la resistencia y el duelo. A propósito de La Ilíada de Teatro de los Andes (2000

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    María Gabriela Aimaretti

    2016-12-01

    Full Text Available Este trabajo describe y analiza la obra La Ilíada (2000 de Teatro de los Andes que, retomando el texto homérico desde el contexto boliviano y latinoamericano, ofrece una interpretación crítica del pasado reciente de las dictaduras cívico-militares y el presente neoliberal. Esa lectura es posible gracias al diseño de una compleja arquitectura discursiva, visual, lingüística —con apelación al quechua y español– y musical —combinando tradiciones vernáculas y europeas–, que reelabora numerosos y variados intertextos. Nutrido de los aportes de la crítica cultural latinoamericana y los estudios de la memoria, y considerando el marco socio-histórico en el que se inserta y con el que discute la obra; este ensayo reflexiona sobre las formas de representación del dolor y la violencia, y las prácticas de la resistencia y de duelo, a propósito de un espectáculo que se postula a sí mismo como la memoria de un pasado-presente traumático del cual es necesario aprender.

  7. Achieving ADA/ISPAD clinical guideline goals is associated with higher insulin sensitivity and cardiopulmonary fitness in adolescents with type 1 diabetes: Results from RESistance to InSulin in Type 1 ANd Type 2 diabetes (RESISTANT) and Effects of MEtformin on CardiovasculaR Function in AdoLescents with Type 1 Diabetes (EMERALD) Studies.

    Science.gov (United States)

    Bjornstad, Petter; Cree-Green, Melanie; Baumgartner, Amy; Coe, Gregory; Reyes, Yesenia Garcia; Schäfer, Michal; Pyle, Laura; Regensteiner, Judith G; Reusch, Jane Eb; Nadeau, Kristen J

    2018-05-01

    Most youth with type 1 diabetes do not meet the American Diabetes Association (ADA) and International Society for Pediatric and Adolescent Diabetes (ISPAD) targets for hemoglobin A1c (HbA1c), blood pressure (BP), lipids, and body mass index (BMI). We hypothesized that ISPAD/ADA goal achievement would be associated with better insulin sensitivity (IS) and cardiopulmonary fitness. IS was quantified as glucose infusion rate (GIR) from a hyperinsulinemic-euglycemic clamp in youth with type 1 diabetes from the RESistance to InSulin in Type 1 ANd Type 2 diabetes (RESISTANT) (n = 86) and Effects of MEtformin on CardiovasculaR Function in AdoLescents with Type 1 Diabetes (EMERALD) (n = 41) cohorts (n = 127; age 15.7 ± 2.2 years, 52% girls). Cardiopulmonary fitness was measured as peak oxygen consumption (VO 2 peak/kg) during upright (RESISTANT) or supine (EMERALD) cycle ergometry and were stratified by cycle type. Goal achievement was defined as HbA1c 35 mg/dL, triglycerides EMERALD participants for supine VO 2 peak. ADA/ISPAD goal achievement was associated with greater IS and cardiopulmonary fitness. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  8. Níveis de aminoácidos sulfurados totais para poedeiras semi-pesadas após a muda forçada Total sulfur amino acids levels for semi heavy weight laying hens after forced molt

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    Antonio Carlos de Laurentiz

    2005-02-01

    Full Text Available Cento e sessenta e duas poedeiras semipesadas anteriormente submetidas à muda forçada foram distribuídas em um delineamento inteiramente ao acaso, com três tratamentos e nove repetições de seis aves para cada. Os tratamentos consistiram no fornecimento de rações contendo 0,45, 0,60 e 0,75% de aminoácidos sulfurados totais (AAST durante 30 dias após o término da muda forçada (fase de pós-muda. Após os 30 dias, cada um dos tratamentos adotados na fase de pós-muda foi desmembrado nos mesmos níveis de AAST, compondo, portanto, um delineamento inteiramente ao acaso em esquema fatorial 3x3 (3 níveis de AAST da fase pós-muda - 0,45; 0,60 e 0,75% x 3 níveis de AAST na fase de produção - 0,45; 0,60 e 0,75%, sendo os tratamentos nesta fase compostos de três repetições de seis aves cada. Na fase de pós-muda, o menor nível de AAST determinou menores valores para consumo de ração (POne hundred and sixty two brown laying hens after the induced molt were randomly assigned to three treatments with nine replications and six birds each. The treatments consisted of 0.45, 0.60 and 0.75% of total sulfur amino acids (TSAA in the diets for 30 days after the end of induced molt (postmolt phase. After 30 days, each one of the treatments used in the postmolt phase was dismembered in the same TSAA levels, composing therefore a completely randomized desing in a factorial arrangement 3x3 (3 levels of TSAA in the postmolt phase - 0.45, 0.60 and 0.75% x 3 TSAA levels in the production phase - 0.45, 0.60 and 0.75%. The treatments in the production phase were composed of three replications of six birds each. At the production phase the performance and egg quality were evaluated for 4 periods of 21 days. At postmolt phase the lower TSAA level (0.45% determined lower values (P<0.01 for feed intake, TSAA intake and body weight. The TSAA levels used in the postmolt phase affected (P<0.05 only the egg weight and the smaller weight were determined by 0

  9. Ílion, a Pátria dos Ventos: O uso da Meteorologia e da Astronomia na Ilíada * Ilion, la Patrie des Vents: l'utilisation de la Meteorologie et l'Astronomie dans l'Iliade

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    RAFAEL VIRGILIO DE CARVALHO

    2014-01-01

    Full Text Available Resumo: Na Grécia Antiga o céu era personificado como um dos deuses primordiais do panteão helênico. Como gerador de tudo o que existe, Urano (Céu abrigava em seu bojo as forças naturais que indicavam a presença dos deuses e dos titãs. Nessa direção, a observação de seus objetos - os metéoroi - era de inestimável valor para a cultura homérica. Homero iluminou as ações dos heróis da Ilíada por meio de analogias com os objetos celestes, os quais mais tarde no século IV a.C. mobilizariam os olhares de Platão e de Aristóteles. Os meteóroi, "objetos naturais suspensos no ar", foram descritos pelo poeta através de certas funções narrativas da epopeia, estruturando assim uma protometeorologia homérica. O presente trabalho procura então levantar certos padrões expressivos encontrados durante a leitura da Ilíada e algumas considerações que os problematizam de modo a iluminar o entendimento sobre tema.Palavras-chave: Mundo homérico – Meteorologia e astronomia – Crença – Mecanismos de linguagem. Résumé: Dans la Grèce antique, le ciel était personnifié comme l'un des dieux primordiaux du panthéon hellénique. Comme un générateur de tout ce qui existe, Uranus (le Ciel logé en elle les forces naturelles qui indiquaient la présence des dieux et des Titans. De cette façon, l'observation des ses objets - les meteóroi - a été d'une valeur inestimable à la culture homèrique. Homère éclarait les actions de l'Iliade grâce a des analogies avec les objets célestes, qui, plus tard dans l'IVe siècle av. J.-C., mobiliseraient les regards de Platon et d'Aristote. Les meteóroi, "les objets naturels en suspension dans l'air", ont été décrits par le poète à travers des certaines fonctions narratives de l'histoire, structurant ainsi une proto-météorologie homérique. Cet article cherche alors à soulever certaines normes de description trouvés au cours de la lecture de l'Iliade et quelques consid

  10. Novos valores de referência para espirometria forçada em brasileiros adultos de raça branca New reference values for forced spirometry in white adults in Brazil

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    Carlos Alberto de Castro Pereira

    2007-08-01

    Full Text Available OBJETIVO: Descrever novas equações de referência para a espirometria em adultos brasileiros saudáveis que nunca fumaram, e comparar os valores previstos atuais com os valores derivados em 1992. MÉTODOS: Equações e limites de referência foram derivados em 270 homens e 373 mulheres, habitantes de oito cidades brasileiras, por espirômetro. A idade variou de 20 a 85 anos nas mulheres e 26 a 86 anos nos homens. Os exames seguiram as normas recomendadas pela Sociedade Brasileira de Pneumologia e Tisiologia. Os limites inferiores foram derivados pela análise do 5º percentil dos resíduos. RESULTADOS: Os valores previstos para capacidade vital forçada (CVF, volume expiratório forçado no primeiro segundo (VEF1 e para as relações VEF1/CVF e VEF1/volume expiratório forçado nos primeiros seis segundos (VEF6 se ajustaram melhor em regressões lineares. Os fluxos ajustaram-se melhor em equações logarítmicas. Em ambos os sexos, maiores estaturas resultaram em menores valores para as relações VEF1/CVF, VEF1/VEF6 e fluxos/CVF. Os valores de referência do VEF1 e da CVF, no presente estudo, foram maiores do que aqueles derivados para adultos brasileiros em 1992. CONCLUSÃO: Novos valores previstos para a espirometria forçada foram obtidos em uma amostra da população brasileira de raça branca. Os valores são maiores do que os obtidos em 1992, provavelmente em decorrência de fatores técnicos.OBJECTIVE: To describe spirometric reference equations for healthy Brazilian adults who have never smoked and to compare the predicted values with those derived in 1992. METHODS: Reference equations for spirometry were derived in 270 men and 373 women living in eight cities in Brazil. Ages ranged from 20 to 85 years in women and from 26 to 86 years in men. Spirometry examinations followed the recommendations of the Brazilian Thoracic Society. Lower limits were derived by the analysis of the fifth percentiles of the residuals. RESULTS: Forced vital

  11. Fiber-reinforced fixed partial dentures: a preliminary retrospective clinical study Próteses parciais fixas reforçadas por fibras: um estudo clínico retrospectivo preliminar

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    Edno Moacir Piovesan

    2006-04-01

    Full Text Available The aim of this study was to evaluate the clinical performance (retention rate of fiber-reinforced composite fixed partial dentures (FPDs. Polyethylene fiber (Ribbond® was used combined with restorative composite during FPDs fabrication. FPDs were placed in thirteen patients in a private clinic. Nineteen FPDs were evaluated. The prosthetic space was filled with only one pontic using extracted teeth (2 cases, acrylic resin teeth (11 cases, or with composite resin (6 cases, combined with Polyethylene fiber. The clinical criterion used was based on retention rate of FPDs. If FPDs were in function in the mouth at the time of examination without previous repair they were classified as Complete Survival (CS restorations. A classification of Survival with Rebonding (SR was assigned in the event of an adhesive failure, but after rebonding the FPD still remained under evaluation. Treatment was classified as a Failure (F if the FPD restoration was lost. The time of evaluation was 41.15 months (±15.13. The FPDs evaluated were retained (CS=94.75%, and no failure was found except for in one situation which required rebonding (SR=5.25%. According to the survival estimation method of Kaplan-Meyer the mean survival time was 42.3 months. At the time of evaluation investigated, polyethylene-reinforced FPDs showed a favorable retention rate in preliminary data.O objetivo deste estudo foi avaliar a performance clínica (percentagem de retenção de próteses parciais fixas reforçadas por fibras. Fibras de polietileno (Ribbond® foram usadas em combinação com resina composta durante a confecção das próteses. Os tratamentos foram realizadas em 13 pacientes, em uma clínica privada., sendo que 19 próteses foram reavaliadas. O espaço protético era preenchido com um pôntico usando o próprio dente extraído (2 casos, dentes de acrílico (11 casos ou confeccionados com resina composta (6 casos, em todas as situações eram empregadas fibras de polietileno. Os

  12. AVALIAÇÃO DOS COEFICIENTES DE SEGURANÇA DOS CÓDIGOS NORMATIVOS PARA REFORÇOS AO CISALHAMENTO EM VIGAS DE CONCRETO ARMADO REFORÇADAS COM PRFC

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    Nara Villanova Menon

    2016-05-01

    Full Text Available RESUMO: O problema da avaliação do cisalhamento em vigas de concreto armado reforçadas por polímeros reforçados com fibras (PRF é um assunto muito complexo. As atuais normas/códigos mais importantes e recomendações de pesquisadores quantificam o cisalhamento por meio de uma simples soma das contribuições do concreto (Vc, do aço (Vsw, e do PRF (Vf. Apresentar comparações entre as formulações analíticas dos mais importantes códigos e recomendações disponíveis na literatura e avaliar os coeficientes de segurança propostos utilizando dados obtidos de resultados provenientes de investigações experimentais é o objetivo deste trabalho. Desenvolveu-se uma série de comparações entre as normas e recomendações NBR 6118 (2014, EUROCODE 2 (1992, ACI 318M (2011, ACI 440.2R (2008, fib BULLETIN 14 - TG 9.3 (2001 e CNR-DT 200 (2004. A base de dados foi feita pelos resultados experimentais de 30 vigas de concreto armado reforçadas. Observou-se que algumas normas são mais restritivas em relação às outras, oferecendo uma menor contribuição ao reforço, sendo, portanto, mais seguras. As informações permitiram demonstrar através de gráficos que o comportamento esperado, possível devido ao uso dos coeficientes de segurança, mantiveram os valores de cálculo muito abaixo dos valores de ruptura. Este trabalho pretende contribuir para a melhor utilização da combinação das principais normas utilizadas. ABSTRACT: The problem of the evaluation of the shear strength in RC beams strengthened with fibre-reinforced polymers (FRP is a very complex subject. The actual most important codes/recommendations quantify the nominal shear strength by a simple sum of the contributions to concrete (Vc, steel (Vsw, and FRP (Vf. This paper presents a broad comparison between the experimental results sourced from a number of experimental investigations and the analytical formulation of the most important codes/recommendations available in

  13. Estudo de oxidação avançada de corantes básicos via reação Fenton (Fe2+/H2O2

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    Thiago Romário Soares Paulino

    2015-09-01

    Full Text Available RESUMOO processo de oxidação avançada do tipo reação Fenton (Fe2+/H2O2 foi estudado neste trabalho para descoloração de dois efluentes sintéticos, contendo os corantes Azul de Metileno (AM e Rodamina B (RB. Experimentalmente, soluções em concentração de 10 mg L-1 dos corantes foram submetidas a diferentes dosagens de agente oxidante (H2O2 e catalisador (Fe2+ em uma temperatura de 27 °C e pH 3. Os resultados obtidos apresentaram altos níveis de remoção de cor, com eficiência da ordem de 96% para o AM e 86% no RB. Os dados mostraram bom ajuste ao modelo cinético. O monitoramento do espectro de absorção dos corantes mostrou uma diminuição da amplitude dos picos relacionados aos grupos cromóforos em ambos compostos, corroborando com os níveis de eficiência alcançados. A análise de remoção de matéria orgânica em termos de Demanda Química de Oxigênio (DQO não acompanhou a mesma taxa de decréscimo de descoloração, obtendo-se reduções de 40,9% para o AM e 25,5% para o RB.

  14. Evidências de validade das Matrizes Progressivas Avançadas de Raven em universitários Validity Evidence of Raven's Advanced Progressive Matrices in university students

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    Milena Oliveira Rosseti

    2009-08-01

    Full Text Available O objetivo do estudo foi encontrar evidências de validade das Matrizes Progressivas Avançadas de Raven em universitários. Participaram 369 universitários de duas universidades privadas do estado de São Paulo, sendo 104 (28,2% do sexo masculino e 265 (71,8% do feminino. Em relação aos cursos, 167 (45,3% são de Psicologia, 111 (30,1% de Administração de Empresas, 54 (14,6% de Gestão de Recursos Humanos e 37 (10% de Pedagogia. Os resultados demonstraram que houve diferença significativa com relação ao gênero, com um melhor desempenho do sexo masculino (t=4,21 e pThe aim of the study was to find validity evidence of Raven's Advanced Progressive Matrices in university students. The sample consisted of 369 university students from two private universities in the state of Sao Paulo, being a 104 (28,2% of the masculine and 265 (71,8% of the feminine. Regarding the courses, 167 (45,3% is of Psychology, 111 (30,1% is of Business Administration, 54 (14,6 % is of Management of Human Resources and 37 (10% is of Pedagogy. The results showed statistically significant difference of sex, with males having better performance in the instrument (t=4.21; p<0.01. The analysis of variance (ANOVA showed significant difference between averages of the courses (F=13,8; p<0,00, and the courses that are differentiated in accordance with the test ad-hoc of Tukey were Administration and Psychology that obtained scores bigger than the others courses. The results demonstrated what the used instrument showed precisely to value aspects of the general intelligence at university students.

  15. Redes personales y capital social en una parroquia rural de la Provincia de Maracaibo (Venezuela a fines del siglo XVIII: La Inmaculada Concepción de La Cañada (1784-1804

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    Luis Rincón Rubio

    2015-07-01

    Full Text Available En los estudios históricos, la expresión “red social” es utilizada principalmente como un concepto metafórico que implica la interconexión de diferentes individuos. Si bien este enfoque permite abordar aspectos funcionales de las redes sociales, no permite analizarlas sistemáticamente desde un punto de vista estructural. Superando el uso metafórico del concepto de red social, se adopta en esta investigación la metodología del Análisis de Redes Sociales (ARS para estudiar las redes personales tejidas durante las dos últimas décadas del siglo XVIII por los agentes sociales detentores de mayor capital social en la parroquia eclesiástica Inmaculada Concepción de La Cañada, provincia de Maracaibo de la antigua Capitanía General de Venezuela, mediante vínculos de parentesco consanguíneo y vínculos derivados de las instituciones eclesiásticas del matrimonio y el bautismo. La utilización de la metodología del ARS permitió ilustrar un enfoque todavía muy poco utilizado en la investigación histórica, y profundizar en aspectos de interés relativos a la creación de vínculos personales, la distribución del capital social y las estrategias de reproducción social puestas en práctica por los habitantes de una comunidad rural de la América Hispana.

  16. What impact do anxiety, depression, perceived control and technology capability have on whether patients with chronic heart failure take-up or continue to use home tele-monitoring services? Study design of ADaPT-HF.

    Science.gov (United States)

    Crundall-Goode, Amanda; Goode, Kevin M; Clark, Andrew L

    2017-04-01

    Home tele-monitoring (HTM) is used to monitor the clinical signs and symptoms of patients with chronic heart failure (CHF) in order to reduce unplanned hospital admissions. However, not all patients who are referred will agree to use HTM, and some patients choose to withdraw early from its use. ADaPT-HF will investigate whether depression, anxiety, low perceived control, reduced technology capability, level of education, age or the severity or complexity of a patient's illness can predict refusal of, or early withdrawal from, HTM in patients with CHF. The study will recruit 288 patients who have been recently admitted to hospital with heart failure who have been referred for HTM. At the time of referral, patients will complete depression (nine-item Patient Health Questionnaire), anxiety (seven-item Generalised Anxiety Disorder questionnaire), perceived control (eight-item revised Controlled Attitudes Scale) and technology capability (ten-item Technology Readiness Index 2.0) screening questionnaires. In addition, data on demographics, diagnosis, clinical examination, socio-economic status, history of comorbidities, medication, biochemistry and haematology will be recorded. The primary outcome will be a composite of refusal of or early withdrawal from HTM. The principle analysis will be made using logistic regression. By establishing which factors influence a patient's decision to refuse or withdraw early from HTM, it may be possible to redesign HTM referral processes. It may be that patients with CHF who also have depression, anxiety, low control and poor technology skills should not be referred until they receive appropriate support or that they should be managed differently when they do receive HTM. The results of ADAPT-HF may provide a way of making more efficient and cost-effective use of HTM services.

  17. Papel dos níveis de BNP no prognóstico da insuficiência cardíaca avançada descompensada Role of BNP levels on the prognosis of decompensated advanced heart failure

    Directory of Open Access Journals (Sweden)

    Antônio Carlos Pereira-Barretto

    2013-03-01

    Full Text Available FUNDAMENTO: A insuficiência cardíaca (IC é doença que cursa com má evolução, especialmente naqueles com IC avançada. A dosagem de peptídeo natriurético tipo B(BNP, ao lado da utilidade no diagnóstico da descompensação cardíaca, vem se mostrando útil na avaliação prognóstica. OBJETIVOS: Verificar se os níveis de BNP identificam quais pacientes evoluiriam pior e se o BNP seria fator independente de mortalidade considerando-se idade, sexo, funções cardíaca e renal e etiologia da cardiopatia. MÉTODOS: 189 pacientes com IC avançada em classe funcional III/IV foram estudados. Todos tinham disfunção sistólica e dosaram-se os níveis de BNP na hospitalização. Analisaram-se as variáveis relacionadas com a mortalidade através de análises univariada e multivariada. RESULTADOS: Os níveis de BNP foram mais elevados nos pacientes que morreram no primeiro ano de seguimento (1.861,9 versus 1.408,1 pg/dL; p = 0,044 e nos chagásicos (1.985 versus 1.452 pg/mL; p = 0,001, e esses pacientes chagásicos tiveram maior mortalidade no primeiro ano de seguimento (56% versus 35%; p = 0,010. Pela curva ROC, o valor de BNP de 1.400 pg/mL foi o melhor preditor de eventos, estando os valores elevados associados a FEVE mais baixa (0,23 versus 0,28; p = 0,002 e maior grau de disfunção renal (ureia média 92 versus 74,5 mg/dL; p = 0,002. CONCLUSÃO: Na IC avançada, os níveis elevados de BNP identificam pacientes com maior potencial de pior evolução. Os pacientes chagásicos apresentam níveis mais elevados de BNP do que as outras etiologias e têm pior evolução.BACKGROUND: Heart failure (HF is a condition with poor outcome, especially in advanced cases. Determination of B-type natriuretic peptide (BNP levels is useful in the diagnosis of cardiac decompensation and has also been proving useful in the prognostic evaluation. OBJECTIVES: To verify whether BNP levels are able to identify patients with a poorer outcome and whether it is an

  18. Fine-Tuning ADAS Algorithm Parameters

    Data.gov (United States)

    U.S. Environmental Protection Agency — With the development of the Connected Vehicle technology that facilitates wirelessly communication among vehicles and road-side infrastructure, the Advanced Driver...

  19. ADA Integrated Environment I. System Specification.

    Science.gov (United States)

    1981-12-01

    1840 Z 4C 0 -M 0 4, Im. ..-. . - S. C- o , z 34 CM o 0 10 L o 0 40. CU 0..4 41 C 1. I3 0 U. .0 ff M S o) M -Ca. C . in C, W W ,a~ 03S. ~ 4333 4 43Ce 3...executing on a target machine. 3.7.7 MAPSE Generation and Support MAPSE Generacion and Support (MGS) shall provide the facilities to develop the MAPSE on

  20. Ada Compiler Validation Implementers’ Guide,

    Science.gov (United States)

    1980-10-01

    Implementers’ Guide 10/l/8O 3-54 3.7.1 Discriminants • direct assignments to disriminant components are forbidden (see 5.2.T). • a...default discriminant values, e.g., type U(SEX: GENDER ) is ... ; requires a discriminant constraint (see 3.7.2 and 3.7.3) when used in an object or...resulting type. Consider the following examples, in which PERSONNAME and PERSONNAME(M) are access subtype indications: type PERSON (SEX: GENDER ) is record

  1. Meningokoki vastu saab end vaktsineerida / Ada Maltseva

    Index Scriptorium Estoniae

    Maltseva, Ada, 1970-

    2008-01-01

    Vt. ka Linnaleht : Tallinn : na russkom jazõke, Linnaleht : Tartu 16. jaan., lk. 7. Tervisekaitseinspektsiooni avalike suhete juht Iiris Saluri räägib meningokokknakkusest ning selle vastu vaktsineerimisest

  2. Real-Time Ada Demonstration Project

    Science.gov (United States)

    1989-05-31

    frequently o;perate from independent oscillators . This results in synchronization being required at initialization and periodically thereafter due to...Project Final Report Specifically, fields after "MSG LENGTH" shall be in a format that is directly compatible with the 80X86 family byte ord- ring . For...page address todsw ;fetch status into AL, NEXT PTR into AN xor aLM ; zero Low byte, Leaving a new pointer sub. ax,eth offset ;correct for memory vs page

  3. ADAS applications for improving traffic safety

    NARCIS (Netherlands)

    Lu, M.; Wevers, K.; Heijden, R.E.C.M. van der; Heijer, T.

    2004-01-01

    Governments in several European countries, and the EU have set challenging targets for the improvement of road traffic safety by the year 2010. In the Netherlands a program for infrastructure measures was launched, to meet the Dutch targets. The ongoing developments in the field of ITS applications

  4. Tríada de Carney incompleta e hipertensión arterial en una mujer joven Incomplete Carney’s triad and arterial hypertension in a young woman

    Directory of Open Access Journals (Sweden)

    Alberto Allievi

    2006-02-01

    Full Text Available Se presenta una el caso de paciente joven, con tríada de Carney incompleta que cursa hipertensión arterial de dos años de evolución y anemia ferropénica grave por pérdida crónica de sangre por tubo digestivo, con tumores gástricos múltiples y paraganglioma pararrenal. No presenta aún desarrollo de condromas pulmonares visibles por tomografía axial computada. En nuestra paciente el paraganglioma no resultó funcionante. Resaltamos que la presencia de tumores gástricos múltiples en un adulto joven debe sugerir la posibilidad de tumores estromales (GIST, cuyo diagnóstico por biopsia endoscópica es difícil debido a su localización profunda, situada en las capas musculares de la pared gástrica. Asimismo queremos remarcar la importancia de las técnicas de marcación descriptas para el diagnóstico preciso. El seguimiento debe ser constante dado el pronóstico incierto de estos tumores. Los condromas pulmonares pueden aparecer años después de la resección del GIST y ser confundidos con metástasis del GIST.The case of young woman with arterial hypertension diagnosed two years before, is here presented; she had a ferropenic anemia caused by digestive loss of blood. Multiple gastric tumors and pararenal non functioning paraganglioma were found. No chondromas were detected. An incomplete Carney’s Triad was diagnosed. We remark that multiple gastric tumors in a young adult suggest the possibility of gastrointestinal stromal tumors (GIST Endoscopic biopsy frequently is not effective because these tumors are deep placed in the muscular gastric layers. The importance of specific techniques for a positive diagnosis are emphasized. Continuous follow up is needed because these tumors have uncertain prognosis. Lung chondromas may appear years later after the GIST was removed and might be confused with GIST metastases.

  5. EL ESTILO DOCENTE UNIVERSITARIO EN RELACIÓN AL TIPO DE CLASE Y A LA DISCIPLINA ENSEÑADA/ TEACHING STYLES AT UNIVERSITY: QUALITATIVE AND QUANTITATIVE ANALYSIS IN TWO DISCIPLINES TAUGHT AND TWO CLASSES’ TYPES

    Directory of Open Access Journals (Sweden)

    Nestor Roselli***

    2010-03-01

    Full Text Available RESUMENEl presente artículo aborda los resultados obtenidos a partir de la utilización de una planilla de observación de clases endos casos paradigmáticos: una cátedra de Ciencias Humanas y otra de Ciencias Exactas. El instrumento permitió registrar, apartir de las verbalizaciones públicas emitidas y los recursos didácticos utilizados, el estilo docente de los profesoresobservados (Jefe de Cátedra y Auxiliar, en cada caso. El análisis de los datos se hizo en dos direcciones: relacionando elestilo docente con los tipos de clases (teóricas y prácticas y las disciplinas que enseñan (Ciencias Humanas o Exactas. Losresultados muestran que existen diferencias en el estilo docente según el tipo de clase y según la disciplina enseñada. Lasprimeras tienen que ver con clases más magistrales o participativas, según que las clases sean teóricas o prácticas; lassegundas conciernen al carácter más discursivo de la enseñanza de asignatura humanística y, más ligada a imágenes, en elcaso de epistemes exactas.ABSTRACTThis paper shows the results obtained from a class observation instrument in two different cases: One in a HumanScience class and the other in an Exact Science class. The tool registered, from the oral verbal expressions and the learningresources used as well, the teaching styles of the professors observed (chief of class and auxiliary in each case. The dataanalysis was done in two ways: by relating the teaching style to the types of classes (theoretical and practical and thesubjects taught (Human Sciences or Exact Sciences. Results show differences between the teaching style according to thetype of class and according to the subject taught. The first ones deal with classical lectures or based on students activitieseither theoretical or practical; the other ones are concerned to the discursive teaching of the Humanistic subject and closerto images, as in the case of exact epistemes.

  6. COMPORTAMENTO EM COMPRESSÃO DE ARGAMASSAS REFORÇADAS COM FIBRAS NATURAIS. I RELAÇÃO TENSÃO-DEFORMAÇÃO EXPERIMENTAL E PROCESSO DE FRATURA

    Directory of Open Access Journals (Sweden)

    Romildo Dias Toledo Filho

    Full Text Available RESUMO Esta é a primeira parte de um artigo dividido em duas partes e visa avaliar, analítica e experimentalmente, o comportamento em compressão de argamassas reforçadas com fibras naturais. No presente artigo pretende-se mostrar, de forma experimental, como a adição de fibras de sisal e coco afeta, em várias frações volumétricas e comprimentos, o comportamento tensão-deformação, em compressão, de duas matrizes de argamassa. A influência dessas fibras no processo de fratura das argamassas é também avaliada. O efeito da substituição parcial do cimento Portland (OPC por micro- sílica e escória de alto forno no comportamento dos compósitos é também discutido. Os resultados indicam que a adição de fibras naturais reduziu a resistência a compressão das matrizes em cerca de 18% a 32% e, de forma desprezível o seu módulo de elasticidade mas, não modificou, de forma significativa, o coeficiente de Poisson. Por outro lado, as fibras confinaram o material retardando a propagação da primeira fissura e aumentando a tenacidade pós-carga de pico do material. Com relação ao processo de fratura da argamassa, os resultados indicam que, até a tensão de ruptura, o efeito da adição de fibras de sisal e coco é similar às características produzidas pelo acréscimo da quantidade de areia na matriz de argamassa. A substituição parcial de OPC por escória e micro-sílica conduziu a misturas com uma resistência a compressão ligeiramente mais alta que a das preparadas apenas com OPC. A substituição do OPC resultou tanto na redução quanto no aumento do módulo de elasticidade, enquanto o coeficiente de Poisson não foi modificado significativamente.

  7. Análise numérica de vigas de concreto armado reforçadas por compósitos formados por fibras de alta resistência e argamassa de cimento

    Directory of Open Access Journals (Sweden)

    C. M. Paliga

    Full Text Available A aplicação de materiais compósitos à base de resinas poliméricas e fibras no reforço de estruturas de concreto armado se tornou uma técnica bastante difundida nos últimos tempos. O uso dos compósitos reforçados com fibras de carbono, ou outros tipos de fibras sintéticas, se consolidou pelas suas excelentes características, tais como elevada resistência, baixo peso, resistência à corrosão, etc. Este material, na forma de lâminas ou laminados, é colado no substrato de concreto através de adesivos à base de epóxi. Apesar do uso do epóxi apresentar excelentes resultados em termos de colagem e resistência, algumas desvantagens podem ser citadas, tais como: baixa permeabilidade, baixa compatibilidade térmica em relação ao concreto, baixa resistência ao fogo, etc. Para evitar alguns desses problemas, um sistema compósito à base de tecidos ou malhas de fibras sintéticas coladas na superfície de concreto com argamassa de cimento pode ser usado. O objetivo deste trabalho é fazer uma análise numérica, através de um modelo não linear de elementos finitos, do comportamento estrutural de vigas de concreto armado reforçadas à flexão com compósitos baseados na combinação de tecidos de fibras sintéticas de alta resistência e argamassa de cimento. Os resultados numéricos são comparados aos resultados experimentais publicados em artigos técnicos internacionais, que demonstram a eficiência da técnica de reforço e a capacidade do modelo numérico.

  8. Ada Compiler Validation Summary Report: Certificate Number: 921004W1.11283, Verdix Corporation, VADS System V/386/486 VAda-110-3232, Version 6.1, NCR Model 3550 under NCR UNIX SVR4 MP-RAS Release 2

    Science.gov (United States)

    1992-11-18

    ho per s moers.. A, Ig V • tine tar ra wK0bM Seig kuise eing] da , estem pilwt• •id mviftrw V.o l neede-, and r•mawft to aoledin of ,oriangiom Sved...written in a self -checking manner and produce a PASSED, FAILED, or NOT APPLICABLE message indicating the result when they are executed. Three Ada...OPTIONS -w (warnings) Suppress warning diagnostics. Diagnostics The diagnostics produced by the VADS compiler are intended to be self -explanatory

  9. Uma contribuição ao processo de soldagem plasma de arco transferido (PTA para posições forçadas A contribution to the plasma transferred arc welding process (PTA in flat, horizontal and overhead positions

    Directory of Open Access Journals (Sweden)

    Víctor Vergara Díaz

    2011-03-01

    Full Text Available Neste projeto foram realizados estudos do processo de soldagem plasma de arco transferido (PTA com o objetivo de contribuir à soldagem em posições forçadas. A tocha de soldagem foi desenvolvida a partir de uma tocha plasma para keyhole, o que permite a utilização de dois modelos de bicos constritores de plasma com diferentes ângulos de convergência para a alimentação do pó, 30 e 60 graus de ângulo de convergência. Com isto abre-se uma nova perspectiva para revestimentos metálicos fora de posição plana e neste contexto se insere a recuperação por soldagem de partes erodidas por cavitação de turbinas hidráulicas. Com o objetivo de conhecer o comportamento do processo fora da posição foram conduzidos alguns experimentos com corrente contínua pulsada, utilizando-se a liga Stellite 6, e comparados com os resultados obtidos na posição horizontal e plana. A liga Stellite 6 vem sendo uma das mais utilizadas por apresentar uma excelente resistência ao desgaste por abrasão, erosão, impacto e cavitação. Foram avaliadas as características geométricas dos cordões, grau de diluição, dureza e microestrutura. Na posição horizontal e sobre-cabeça foram encontrados resultados inéditos, tornando o LABSOLDA pioneiro em revestimentos fora da posição plana neste processo de soldagem.In this Project, besides of producing an equipment of plasma welding with injection of powder (PTA, studies were done with the purpose of contributing to the welding in flat, horizontal and overhead. The welding torch was developed starting from a Plasma torch for the keyhole. Furthermore, the adaptation proyect allows the use of two constrictor plasma nozzles with different convergency angles for powder feeding. For this proyect, two models were built, a nozzle with a 30º angle and another one with a 60 º convergency angle. With this, a new perspective is opened for metallic coverings out of a flat position and within this context it is

  10. Efeito de diferentes métodos de muda forçada sobre o desempenho de poedeiras comerciais Effect of different methods of molt induction on performance of commercial laying hens

    Directory of Open Access Journals (Sweden)

    Rubens Bastos Ramos

    1999-01-01

    Full Text Available Este experimento foi realizado para comparar o desempenho de poedeiras comerciais após serem submetidas a diferentes métodos de muda forçada. Noventa e seis poedeiras Hy Line brancas com 85 semanas de idade foram distribuídas em delineamento de blocos ao acaso, com quatro tratamentos. Os tratamentos foram: T1 - método convencional constituído da retirada do alimento durante os 12 primeiros dias do experimento; T2 - dieta com alto teor de zinco; T3 - dieta com baixa energia fornecida em quantidade limitada (45 g/ave.dia; e T4 - dieta com baixa energia fornecida à vontade. Os dados de produção após a muda foram registrados durante cinco períodos de 28 dias. A porcentagem de postura (ave/dia e a conversão alimentar (kg ração/kg ovo foram melhores para as aves submetidas à muda por intermédio dos métodos convencional (T1, alto teor de Zn (T2 e dieta com baixa energia fornecida à vontade (T4 em relação às aves submetidas à dieta com baixa energia fornecida em quantidade diária limitada (T3. O peso do ovo foi mais alto para as aves dos tratamentos convencional (T1 e dieta com baixa energia à vontade (T4 em relação às aves alimentadas com dietas com alto teor de zinco (T2 ou com baixa energia fornecida em quantidade limitada (T3. Os métodos de muda usados não influíram no consumo de ração. O uso de dieta com baixa energia, quando fornecida à vontade, e dieta com alto teor de Zn, como métodos para indução de muda, resultou em desempenho similar ao obtido com o método convencional.This experiment was carried out to compare the productive performance of commercial laying hens after being under different methods of induced molting. Ninety-six Hy-Line white laying hens, 85 weeks of age were allotted to a randomized block design with four treatments. The treatments were: T1 - the conventional method consisted of feed withdrawal during the 12 first days of the experiment; T2 - diet of high-zinc content; T3 - low

  11. Métodos alternativos de restrição alimentar na muda forçada de poedeiras comerciais Alternative methods of feed restriction in the forced molt of laying hens

    Directory of Open Access Journals (Sweden)

    Karina Márcia Ribeiro de Souza

    2010-02-01

    Full Text Available Foram avaliados métodos alternativos de restrição alimentar qualitativa em comparação à técnica convencional de muda forçada. Utilizaram-se 480 galinhas Babcock de 78 semanas distribuídas em três níveis de restrição alimentar (100, 75 e 50% e três percentuais de redução de peso corporal (15, 20 e 25%, cada um com cinco repetições de 32 aves. Quando as aves atingiram o percentual de redução de peso corporal, determinaram-se o volume globular, os percentuais de ovário, oviduto, moela, intestino e gordura abdominal e o comprimento de oviduto. A partir do 28º dia e durante cinco períodos de 28 dias, observaram-se as características quantitativas e qualitativas de produção pós-muda. O maior período de restrição foi observado no nível de 50% e proporcionou menores percentuais de gordura abdominal (0,66%, ovário (0,60%, oviduto (0,77% e comprimento de oviduto (32 cm. O percentual de produção de ovos foi maior no primeiro período para as aves submetidas aos métodos de 75 e 100% de restrição com 15 e 20% de redução de peso, respectivamente. Entretanto, para as aves com 50% de restrição e 25% de redução de peso, as maiores produções (86,80 e 83,20% ocorreram no quarto e quinto períodos. A restrição alimentar qualitativa, em 50% da dieta com ração e casca de arroz, por ser menos agressiva, proporciona melhores condições de bem-estar e facilita o manejo da granja.Alternative methods were assessed of qualitative feed restriction compared to the conventional forced molt technique. Four hundred and eighty Babcock hens were used distributed in three levels of feed restriction (100, 75 and 50% and three body weight reduction percentages (15, 20 and 25%, with five replications of 32 hens. When the birds reached the body weight reduction percentage the packed cell volume, percentages of ovary, oviduct, gizzard, intestine, abdominal fat and oviduct length were determined. Starting on day 28 and during five 28-day

  12. Analysis of cardiovascular system responses to forced vital capacity in COPD Análise das respostas do sistema cardiovascular ao teste de capacidade vital forçada na DPOC

    Directory of Open Access Journals (Sweden)

    Felipe A. R. Mendes

    2011-04-01

    Full Text Available BACKGROUND: The forced vital capacity (FVC test is routinely performed to evaluate pulmonary function in patients with chronic obstructive pulmonary disease (COPD. However, the influence of the FVC maneuver on the cardiovascular system of patients with COPD is poorly understood. OBJECTIVES: To analyze the behavior of heart rate (HR, blood pressure (BP and heart rate variability (HRV during the FVC test in COPD patients. METHODS: Nineteen men with COPD (72±7 years, GOLD stage I=3, II=5, III=7 and IV=4 patients performed the FVC test while having their HR monitored. HRV was assessed in time (rMSSD and frequency domains (LF, HF and LF/HF at rest, before and after the best FVC maneuver. BP was measured at rest, immediately before and at the end of the test, as well as 10 minutes after the end of the test. RESULTS: At the beginning of the FVC maneuver, HR decreased (pCONTEXTUALIZAÇÃO: O teste de capacidade vital forçada (CVF é rotineiramente realizado na avaliação da função pulmonar de pacientes com doença pulmonar obstrutiva crônica (DPOC. Entretanto, permanece pouco compreendida a influência do teste de CVF sobre o sistema cardiovascular de pacientes com DPOC. OBJETIVOS: Analisar o comportamento da frequência cardíaca (FC, pressão arterial (PA e variabilidade da frequência cardíaca (VFC no teste de CVF na DPOC. MÉTODOS: Dezenove homens com DPOC (72 ± 7 anos, no estágio de gravidade GOLD I=3, II=5, III=7 e IV=4 pacientes realizaram a manobra de CVF e tiveram sua FC monitorada durante todo o exame, e a VFC analisada nos domínios do tempo (rMSSD e da frequência (BF, AF e BF/AF durante o repouso, antes e após a melhor manobra de CVF. A PA foi analisada no repouso, imediatamente ao final da manobra de CVF e 10 minutos após o término de todos os testes. RESULTADOS: Ao início da manobra de CVF, a FC reduziu (p<0,001 e, em seguida, aumentou progressivamente até o final do teste (p<0,001. Após término da manobra, a FC continuou

  13. Efeitos de diferentes padrões respiratórios no desempenho e na organização temporal das braçadas do nado "Crawl" Effects of different breathing patterns on the performance and the arm stroke in the front Crawl

    Directory of Open Access Journals (Sweden)

    Marcos Roberto Apolinario

    2012-03-01

    Full Text Available O objetivo deste estudo foi investigar os efeitos de diferentes padrões respiratórios no desempenho e na organização temporal das braçadas do nado "Crawl" de atletas de elite. Vinte e um jovens atletas do gênero masculino participaram de forma voluntária do estudo. Eles foram filmados nadando 25 m do nado "Crawl", em velocidade máxima, em quatro condições de respiração: inspiração para o lado preferido (LP; para o lado não preferido (LNP; bilateral (B; e, sem respiração (S. Duas filmadoras digitais (60 fps captaram as imagens que foram analisadas através do "software" Kinovea 0.8.7 nos 10 metros centrais do percurso. Para análise foram consideradas medidas de desempenho e de organização temporal das braçadas. Os resultados permitiram concluir que o padrão respiratório afeta o desempenho de atletas jovens de elite. Mostraram que, em termos de velocidade, tempo, frequência e comprimento de braçada, é mais vantajosa a condição de nadar "Crawl" em apneia (S que em qualquer das condições com inspiração (B, LP e LNP. Portanto, o padrão preferido de respiração, não necessariamente, corresponde ao mais eficiente em termos do desempenho. Assim, professores e técnicos de Natação deveriam incentivar a prática e o emprego do padrão em apneia como estratégia tática para nadadores velocistas. Em relação à braçada, os resultados mostraram que diante da modificação do padrão respiratório, nadadores peritos jovens mantêm a estrutura temporal das braçadas direita e esquerda (aspectos invariantes da braçada bem como a coordenação entre os braços inalterada enquanto efetuam ajustes na fase aérea da braçada (aspectos variantes. Assim sendo, atletas jovens de elite apresentam braçada com relativa autonomia frente ao componente respiração e nadam efetuando ajustes considerando a economia de recursos.The aim of this study was to investigate the effects of different breathing patterns on the performance and

  14. Utilização da nebulização e ventilação forçada sobre o desempenho e a temperatura da pele de suínos na fase de terminação Effect of nebulization and artificial ventilation on the performance and skin temperature of finishing swine

    Directory of Open Access Journals (Sweden)

    Luiz Euquério de Carvalho

    2004-12-01

    Full Text Available O experimento foi realizado com o objetivo de avaliar os efeitos da nebulização e ventilação forçada sobre o desempenho e a temperatura da pele de suínos na fase de terminação. Utilizaram-se 137 animais (Landrace x Large White x Duroc machos castrados e fêmeas, distribuídos em um delineamento de blocos ao acaso, com dois tratamentos de oito repetições por tratamento, com média de oito animais/baia. Os tratamentos utilizados foram: T1 = sem nebulização de água e ventilação forçada e T2 = com nebulização de água e ventilação forçada. Durante o período experimental, a temperatura média observada foi de 26,32ºC (variando de 23,32 a 30,72ºC e a umidade relativa do ar média, de 64,5%. Os resultados não demonstraram diferenças significativas entre os tratamentos utilizados para as variáveis ganho de peso médio diário, consumo de ração médio diário e conversão alimentar. Entretanto, a nebulização de água associada à ventilação forçada apresentou menores valores de temperatura da pele, indicando melhor conforto aos animais. Não é necessário o uso de nebulização e ventilação forçada em instalações para suínos na fase de terminação, pois, apesar da melhoria no conforto dos animais (temperatura da pele, não trouxe benefício sobre o desempenho dos mesmos.An experiment was carried out to evaluate the effects of nebulization and artificial ventilation on the performance and skin temperature of finishing swine. Castrated males and females (n = 137; Landrace x Large White x Duroc were allotted to two treatments by using a radomized bolck design, with eight replicates: T1 = pens without either nebulization or artificial ventilation; T2 = pens with both nebulization and artificial ventilation. There was an average of eight animals per each pen. During the experimental period, average air temperature was 26.32ºC (from 23.32 to 30.72ºC and humidity, 64.5%. No signifgicant effects of treatments on

  15. Tıbbi Adaçayı (Salvia officinalis L.’nda Farklı Hasat Zamanlarının Uçucu Yağ ve Fenolik Bileşikler ile Antioksidan Aktivite Üzerine Etkisi

    Directory of Open Access Journals (Sweden)

    Müge BAŞYİĞİT

    2016-11-01

    Full Text Available Bu araştırma, bir yıl süreyle 12 ayı temsil edecek şekilde farklı zamanlarda hasat edilen tıbbi adaçayı (Salvia officinalis L.’nın herba ve yaprak verimi, yaprakların taşıdığı uçucu yağ oranı ve kompozisyonu, ekstrede  Folin-Ciocalteu kolorimetrik metodu kullanılarak toplam fenolik madde miktarı, fenolik bileşikleri, serbest radikal süpürücü aktivitesi (DPPH ve demir iyonu indirgeme gücü (FRAP yöntemlerine göre antioksidan aktivitelerini belirlemek amacıyla yapılmıştır. Tıbbi adaçayında taze herba verimi 500.0-961.0 kg/da, kuru herba verimi 223.4-556.6 kg/da, kuru yaprak verimi 129.6-367.2 kg/da, uçucu yağ oranı %0.83-3.33, toplam fenolik madde miktarı 14.54-30.83 mg/g arasında değişim göstermiştir. Yaz ve güz aylarında hasat edilen bitkilerin herba ve yaprak verimleri, uçucu yağ oranları ve verimleri ile toplam fenolik madde miktarları kış ve bahar aylarında hasat edilen bitkilere göre daha yüksek bulunmuştur. Tıbbi adaçayının uçucu yağ kompozisyonunu oluşturan en önemli bileşenlerin 1,8-sineol (%11.93-31.87, α-tuyon (%15.72-26.26, β-tuyon (%4.51-27.67 ve kamfor (%3.65-23.02 olduğu, 1,8-sineol ve kamfor oranları ilkbahar aylarında daha düşük oranlarda, α- ve β-tuyon oranları ise ilkbahar aylarında daha yüksek oranlarda bulunduğu tespit edilmiştir. Tıbbi adaçayının en önemli fenolik bileşenlerinin ise rosmarinik asit (15.15-100.57 mg/g, naringin (9.59-41.81 mg/g, hesperidin (9.80-53.26 mg/g ve rutin (0.73-10.04 mg/g olduğu, en yüksek antioksidan aktivite Mayıs ve Haziran aylarında biçilen ve en düşük antioksidan aktivite ise Mart ve Nisan aylarında biçilen tıbbi adaçayı yapraklarında gözlenmiştir.

  16. Ada (Trade Name) Training Curriculum. Basic Ada Programming L202 Teacher’s Guide. Volume 1.

    Science.gov (United States)

    1986-01-01

    4 . (A) 0 0 U)n c ~zz 0 L Iw m 0 0 W 0 4) 4 () cc 0 V) >- Z o - E z I x -j 0 C. m =zW ccZ- " I- 0 0z o ) aCCa - - z 0 N I--* S a-. ax a- c w Sn% L) C...oo U) 0 cc c C..) f8 4 (A U3 0 )0 C 1-- 00. _ zw w Ca41 LI (A) x Ř) cc (A w I- %__ _ 414 AjC CL W 0 64fl4 6-410 0 0h cr. U m L 0 a. 646)* w C.41 C w...Enl 0 wL U) W I cr. 0 w IL w 0 z L) w 0 u W F8 ~- - IL W >) " cr.0 0 Z x () U) IL W Z 0 U) - wi 0 4c 1 IL Un C 0 r C, wi 0 Z W w. w Ww i CL 00 03- z

  17. Validade do teste de 30 minutos (T-30 na determinação da capacidade aeróbia, parâmetros de braçada e performance aeróbia de nadadores treinados Validity of 30 minutes test (T-30 in aerobic capacity, stroke parameters and aerobic performance determination of trained swimmers

    Directory of Open Access Journals (Sweden)

    Rafael Deminice

    2007-06-01

    Full Text Available O objetivo do presente estudo foi verificar a utilização da velocidade de 30 minutos (VT-30, freqüência de braçada (fB, comprimento de braçada (CB e índice de braçada (IB, obtidos no teste T-30, como métodos não-invasivos para determinação da performance aeróbia e técnica de nadadores treinados. Catorze nadadores submeteram-se a três esforços de 400m (85, 90 e 100% do esforço máximo para determinação da velocidade de limiar anaeróbio (VLan correspondente à concentração fixa de 3,5mM de lactato e um esforço máximo de 30 minutos (VT-30. fB, CB e IB foram calculados nos 10m centrais da piscina (nado limpo para o teste T-30 (fBT-30, CBT-30 e IBT-30 e progressivo. Através da relação entre VLan e parâmetros de braçada no teste progressivo, determinaram-se freqüência de braçada de limiar (fBLan, comprimento de braçada de limiar (CBLan e índice de braçada de limiar (IBLan. O tempo para realizar 400m em máximo esforço foi considerado como parâmetro de performance (P400. Não foi encontrada diferença significativa entre VLan (1,29 ± 0,07m.s-1 e VT-30 (1,29 ± 0,08m.s-1, que ainda apresentaram alta correlação (r = 0,90. Os valores de fBLan (33,6 ± 4,14 ciclos/min e fBT-30 (34,9 ± 3,53 ciclos/min e de CBLan (2,09 ± 0,20m/ciclo e CBT-30 (2,09 ± 0,20m/ciclo também não foram significativamente diferentes. Correlações significativas (p The aim of the present study was to verify the use of the 30 minutes velocity (VT-30, stroke rate (SR, stroke length (SL and stroke index (SI, obtained in T-30 test, as non-invasive methods for trained swimmer's aerobic performance and technical determination. Fourteen swimmers accomplished three efforts along 400 m (85, 90 and 100% of the maximum effort for anaerobic threshold speed determination (ATS corresponding to 3.5 mM lactate fixed concentration, as well as a 30 minutes maximal effort (VT-30. SR, SL, and SI were calculated within the 10 m midsection of the swimming pool

  18. Avaliação da atenuação de ruído em diferentes sistemas de admissão de ar externo por ventilação forçada, usadas em edificações residenciais

    OpenAIRE

    Winck, Scheila Simone

    2012-01-01

    Resumo: Esta pesquisa aborda a problemática da propagação do ruído através da ventilação, e o seu objetivo foi avaliar a atenuação de ruído em diferentes sistemas de admissão de ar externo por ventilação forçada, para uso em edificações residenciais. Partiu-se do pressuposto de que um grande número de residências, ao utilizar a ventilação natural, por meio de janelas abertas, sofre com o ruído vindo do ambiente externo. Sendo assim, para mitigar o problema deste ruído intrusivo, deixa-se d...

  19. F. M. Dostoyevski’nin ‘‘Ölü Evinden Anılar’’, A. P. Çehov’un ‘‘Sahalin Adası’’ ve V. Şukşin’in ‘‘Kızıl Kartopu’’ Eserlerinde Tutuklu Psikolojisi

    OpenAIRE

    Şahinkaya, Nuray

    2014-01-01

    Bu çalışmada, Dostoyevski döneminden itibaren tutuklu psikolojisi, tutukluların karışlaştıkları zorluklar ve bunların ruh dünyalarına nasıl yansıdığı, F. M. Dosoyevski’nin ‘‘Ölü Evinden Anılar’’, A. P. Çehov’un ‘‘Sahalin Adası’’ ve V. Şukşin’in ‘‘Kızıl Kartopu’’ eserleri üzerinden incelenerek anlatılacaktır.

  20. Técnica de oscilações forçadas na análise da resposta broncodilatadora em voluntários sadios e indivíduos portadores de asma brônquica com resposta positiva Using the forced oscillation technique to evaluate bronchodilator response in healthy volunteers and in asthma patients presenting a verified positive response

    Directory of Open Access Journals (Sweden)

    Juliana Veiga Cavalcanti

    2006-04-01

    Full Text Available OBJETIVO: Analisar, através da técnica de oscilações forçadas, pacientes asmáticos com resposta broncodilatadora positiva pelo laudo espirométrico e comparar esses resultados com os obtidos em indivíduos sadios. MÉTODOS: Foram analisados 53 indivíduos não tabagistas, sendo 24 sadios sem história de doença pulmonar e 29 asmáticos com resposta broncodilatadora positiva segundo o laudo espirométrico. Todos foram submetidos à técnica de oscilações forçadas e a espirometria antes e após vinte minutos da administração de salbutamol spray (300 g. Os parâmetros derivados da técnica de oscilações forçadas foram: resistência total, reatância total, resistência extrapolada para o eixo y, coeficiente angular da reta de resistência e complacência dinâmica. Na espirometria, os parâmetros utilizados foram o volume expiratório forçado no primeiro segundo e a capacidade vital forçada. RESULTADOS: No grupo controle, a utilização do broncodilatador produziu alteração significativa na resistência extrapolada para o eixo y (p OBJECTIVE: To use the forced oscillation technique to evaluate asthma patients presenting positive bronchodilator responses (confirmed through spirometry and compare the results with those obtained in healthy individuals. METHODS: The study sample consisted of 53 non-smoking volunteers: 24 healthy subjects with no history of pulmonary disease and 29 asthmatics presenting positive bronchodilator response, as determined through analysis of spirometry findings. All of the subjects were submitted to forced oscillation technique and spirometry immediately before and 20 minutes after the administration of salbutamol spray (300 g. The parameters derived from the forced oscillation technique were total respiratory resistance, total respiratory reactance, resistance extrapolated to the y axis, the slope of resistance, and dynamic compliance. The parameters measured in the spirometry evaluation tests were forced

  1. Estudio comparativo de cimentaciones aisladas en la ciudad de Cuenca diseñadas por el método de la presión admisible con los obtenidos aplicando el método de los estados límites

    OpenAIRE

    Cabrera Palacios, Eduardo Guillermo

    2010-01-01

    En este trabajo se realiza un estudio comparativo de cimentaciones aisladas en la ciudad de Cuenca, diseñadas por el método de la Presión Admisible con los obtenidos aplicando el método de los Estados Limites; se analiza el problema de los métodos de diseño de cimentaciones utilizados en la ciudad de Cuenca, estableciéndose como objetivo primordial el demostrar que para el diseño de cimentaciones superficiales, el método que permite diseñar cimentaciones más económicas es el método de los Est...

  2. Determinação de massa fresca, massa seca, água e cinzas totais de folhas de Cissus verticillata (L. Nicolson & C. E. Jarvis subsp. verticillata e avaliação do processo de secagem em estufa com ventilação forçada

    Directory of Open Access Journals (Sweden)

    T. V. BRAGA

    2009-01-01

    Full Text Available

    Cissus verticillata (L. Nicolson & C. E. Jarvis subsp. verticillata (Vitaceae é conhecida popularmente como insulina vegetal, cortina japonesa, uva-brava, anil trepador e cipó-pucá e utilizada na medicina popular na forma de chá das folhas no tratamento da diabetes, como antiinflamatório, antiepilético, antihipertensivo, antitérmico, antireumático, antigripal e contra infecções respiratórias. O objetivo deste estudo foi avaliar os teores de massa fresca, massa seca, percentual de água e percentual de cinzas totais, visando melhoria das condições de secagem, armazenamento, dispensação e uso pela população. As folhas da espécie foram coletadas no bairro Antônio Dias, Ouro Preto, Minas Gerais, Brasil. Foram selecionadas, lavadas e secas em estufa com ventilação forçada à 45ºC e determinou-se as cinzas totais e perda por dessecação (através do método gravimétrico, ambos de acordo com a Farmacopéia Brasileira. Os resultados mostraram que as folhas de C. verticillata subsp. verticillata possuem alto teor de água. O processo de secagem em estufa de ventilação forçada, a temperatura de 45ºC, foi eficaz, proporcionando folhas com 11,47% de umidade e 17,99% de cinzas totais. Palavras-chave: Cissus verticillata; insulina vegetal; qualidade; gravimetria.

  3. Associação entre evolução da função cognitiva e mortalidade após a alta hospitalar em pacientes idosos com insuficiência cardíaca avançada

    Directory of Open Access Journals (Sweden)

    Ochiai Marcelo E.

    2004-01-01

    Full Text Available OBJETIVO: Avaliar a associação entre a evolução do desempenho cognitivo e o prognóstico de idosos após compensação de insuficiência cardíaca avançada. MÉTODOS: Selecionados, consecutivamente, 31 pacientes internados com insuficiência cardíaca classe IV da New York Heart Association, com idade > 64 anos (68 ±7 e fração de ejeção < 0,45 (0,38 ± 0,06. Submetidos a testes cognitivos (digit span, digit symbol, letter cancellation, trail making A e B e teste de caminhada de 6min, 4 dias antes da alta (T1 e 6 semanas após (T2, cujos desempenhos foram comparados pelo teste T. O valor prognóstico dos escores dos testes cognitivos foram analisados pela regressão logística e o valor de maior acurácia dos testes associado com o prognóstico determinado pela ROC curve. RESULTADOS: Após 24,7 meses, 17 (55% pacientes faleceram. Os desempenhos ao teste de caminhada e maioria dos testes cognitivos melhoraram entre T1 e T2. O escore do digit span entre os sobreviventes variou de 3,9 para 5,2 (p=0,003, permanecendo inalterado entre os que faleceram (4,1para 3,9; p=0,496. Melhora < 0,75 pontos no escore foi associada à mortalidade (risco relativo de 8,1; p=0,011. CONCLUSÃO: Em idosos, após a compensação de insuficiência cardíaca avançada, a ausência de melhora evolutiva do desempenho cognitivo foi associada a pior prognóstico.

  4. Envelhecimento de cachaça sob circulação forçada e aeração
    Aging of cachaça under forced circulation and aeration

    Directory of Open Access Journals (Sweden)

    M. C. C. BORRAGINI

    2010-09-01

    Full Text Available

    O envelhecimento é um procedimento que melhora a qualidade da cachaça, resultando em um produto compatível com as crescentes exigências dos mercados externo e interno. A redução do tempo de envelhecimento, maior obstáculo à adoção desta etapa na produção da cachaça, tem sido testada em função da economia que pode representar e também como uma forma de estimular e difundir a adoção desta prática. Foram objetivos desse estudo avaliar a redução do tempo de envelhecimento da cachaça, utilizando a circulação forçada da bebida em ancorotes de carvalho (Quercus sp, e verifi car o efeito da presença de ar no sistema introduzindo uma etapa de aeração, realizada diariamente durante doze minutos. As amostras assim obtidas foram comparadas com amostras do mesmo lote, submetidas, porém, ao processo tradicional de envelhecimento. Os resultados revelaram que as amostras de cachaça submetidas ao processo de envelhecimento forçado sob aeração apresentaram, ao longo de seis meses, menor extração dos componentes da madeira, menor teor de acidez e aceitação ligeiramente superior em relação aos atributos cor, aroma, sabor, impressão global, sabor adocicado, sabor amadeirado e agressividade, quando comparadas às amostras submetidas ao envelhecimento tradicional, revelando que a injeção de ar no sistema de circulação forçada pode influenciar positivamente algumas características físicoquímicas e sensoriais.

  5. Avaliação radiográfica da neoformação óssea induzida pela técnica de erupção ortodôntica forçada Radiological evaluation of bone growth induced by forced orthodontical eruption technique

    Directory of Open Access Journals (Sweden)

    Paulo de Tarso Barbosa Moreira

    2002-11-01

    Full Text Available Neste relato de caso a radiografia panorâmica é um elemento de importância como auxiliar no diagnóstico terapêutico inicial e depois como suporte no seguimento do caso até o final do tratamento. O caso aqui apresentado é uma abordagem interdisciplinar entre ortodontia e periodontia, em que uma paciente com doença periodontal avançada foi tratada pela técnica de erupção ortodôntica forçada e teve, ao final do tratamento, sua reabilitação conseguida com crescimento ósseo e gengival num primeiro instante e colocação de implantes e próteses dentárias numa abordagem também inovadora de carregamento protético imediato, ou seja, implantes e dentes colocados com 48 horas de diferença. O resultado alcançado aponta que nossos estudos devem prosseguir, visto que o crescimento ósseo foi conseguido sem a necessidade de enxerto, o tempo do tratamento não superou os 120 dias e que no futuro devemos obter resultados que colaborem para a superação de doenças periodontais graves sem varias etapas cirúrgicas, diminuindo o tempo de tratamento, morbidade e custos para o paciente.In this case report we discuss the importance of panoramic x-ray as an auxiliary tool for the diagnosis, initial treatment and follow-up of patients with periodontal disease. The case presented involved an interdisciplinary approach between orthodontics and periodontics. A female patient with advanced periodontal disease was treated with the forced orthodontical eruption technique that resulted in bone and gingival growth at the end of the treatment. Placement of the implants and dental prostheses was also performed in an innovative approach of immediate prosthetic loading, i.e. implants and teeth placed within a 48 hours interval. These results indicate that our studies should continue since bone growth was obtained without a bone graft, the time of the treatment did not exceed 120 days, and that we may in future obtain further results that will contribute to

  6. O efeito do tratamento térmico a 300 ºC na conectividade da estrutura de poros de argamassas de cimento Portland reforçadas por fibras de polipropileno The effect of heat-treatment at 300 ºC on pore structure connectivity of Portland cement mortars reinforced by polypropylene fibers

    Directory of Open Access Journals (Sweden)

    E. C. Amaral

    2012-06-01

    Full Text Available A degradação térmica a 300 ºC de argamassas de cimento Portland reforçada por fibras de polipropileno foi investigada. Foi proposto um modelo computacional para a avaliação qualitativa da conectividade da estrutura de poros. Os resultados revelaram a degradação das argamassas com a temperatura dos tratamentos térmicos. A conectividade da estrutura de poros aumentou com a temperatura do tratamento térmico para as argamassas com fibra. Os resultados também mostraram um aumento da conectividade da estrutura de poros para as argamassas com fibra não submetidas à alta temperatura.Thermal degradation at 300 ºC of polypropylene fiber reinforced Portland cement mortars was investigated. A geometric modeling considering pore with cylindrical shape was also used in order to do quantitative evaluation of pore structure's connectivity. The results revealed thermal degradation of the mortars by high temperature. The pore structure connectivity increased with thermal treatment temperature for mortar samples with fiber content. The test results also showed pore structure connectivity increase for non-heat treated fibered mortars.

  7. QUEST/Ada (query utility environment for software testing of Ada: The development of a program analysis environment for Ada, task 1, phase 3

    Science.gov (United States)

    Brown, David B.

    1991-01-01

    The results of research and development efforts of the first six months of Task 1, Phase 3 of the project are presented. The goals of Phase 3 are: (1) to further refine the rule base and complete the comparative rule base evaluation; (2) to implement and evaluate a concurrency testing prototype; (3) to convert the complete (unit-level and concurrency) testing prototype to a workstation environment; and (4) to provide a prototype development document to facilitate the transfer of research technology to a working environment. These goals were partially met and the results are summarized.

  8. Escore para avaliação do estado nutricional: seu valor na estratificação prognóstica de portadores de cardiomiopatia dilatada e insuficiência cardíaca avançada Score for nutritional status evaluation: the role played in the prognostic stratification of dilated cardiomyopathy and advanced heart failure patients

    Directory of Open Access Journals (Sweden)

    Luiz Guilherme Veloso

    2006-08-01

    Full Text Available OBJETIVO: Desenvolver método de avaliação do estado nutricional do paciente através de escore que expresse o estado nutricional de maneira universal e verificar se esse escore seria eficaz na estratificação prognóstica de pacientes com insuficiência cardíaca (IC avançada. MÉTODOS: Para compor o escore foram selecionados métodos de avaliação que procurassem quantificar forma de medida do estado nutricional: a porcentagem ideal do peso, a espessura da prega tricipital, os percentis da circunferência da massa muscular do braço, os níveis séricos de albumina, a contagem global de linfócitos. Para validá-lo, aplicou-se o escore num grupo de 95 pacientes com idade inferior a 65 anos, sem evidências de doenças consumptivas e analisou-se se esse escore manteria correlação com os dados clínicos da IC e permitiria estratificar o prognóstico. RESULTADOS: A situação nutricional esteve alterada nos pacientes e escore elevado sugerindo desnutrição moderada ou intensa foi observado em 31/95 (32,6% dos casos. Não houve correlação entre os valores do escore nutricional, duração dos sintomas e grau de disfunção ventricular. Os pacientes com escore nutricional elevado apresentaram tendência de maior mortalidade (p=0,0606. CONCLUSÕES: Os dados sugerem que a desnutrição atinge cerca de 1/3 dos pacientes com IC avançada. Um escore que englobou cinco parâmetros de avaliação nutricional teve boa correlação com a avaliação clínica e permitiu avaliar globalmente a desnutrição de portadores de IC. Escore superior a 8 identificou pacientes com maior probabilidade de morrer, confirmando que pacientes mais desnutridos têm pior evolução.OBJECTIVE: Develop a method for the evaluation of patient’s nutritional status through a score that expresses universal nutritional status, as well as investigate if that score would be efficient for the prognostic stratification of advanced heart failure (HF pts. METHODS: The score was

  9. Approach to suspected food allergy in atopic dermatitis. Guideline of the Task Force on Food Allergy of the German Society of Allergology and Clinical Immunology (DGAKI) and the Medical Association of German Allergologists (ADA) and the German Society of Pediatric Allergology (GPA).

    Science.gov (United States)

    Werfel, Thomas; Erdmann, Stephan; Fuchs, Thomas; Henzgen, Margot; Kleine-Tebbe, Jörg; Lepp, Ute; Niggemann, Bodo; Raithel, Martin; Reese, Imke; Saloga, Joachim; Vieths, Stefan; Zuberbier, Torsten

    2009-03-01

    The following guideline of the "Arbeitsgruppe Nahrungsmittelallergie der DGAKI" (Task Force on Food Allergy of the German Society of Allergology and Clinical Immunology) and the ADA ("Arzteverband Deutscher Allergologen", Medical Association of German Allergologists) and the GPA (German Society of Pediatric Allergology) summarizes the approach to be taken when food allergy is suspected in patients with atopic dermatitis (neurodermatitis, atopic eczema). The problem is clinically relevant because many patients assume that allergic reactions against foods are responsible for triggering or worsening their eczema. It is important to identify those patients who will benefit from an elimination diet but also to avoid unnecessary diets. Elimination diets (especially in early childhood) are associated with the risk of malnutrition and additional emotional stress for the patients. The gold standard for the diagnosis of food-dependent reactions is to perform placebo-controlled, double-blind oral food challenges because specific IgE, prick tests and history often do not correlate with clinical reactivity. This is particularly true in the case of delayed eczematous skin reactions. Diagnostic elimination diets should be used before an oral provocation test. If multiple sensitizations against foods are discovered in a patient, an oligoallergenic diet and a subsequent stepwise supplementation of the nutrition should be performed. If a specific food is suspected of triggering food allergy, oral provocation should be performed after a diagnostic elimination diet. As eczema-tous skin reactions may develop slowly (i. e. within one or two day), the skin be inspected the day after the provocation test and that a repetitive test be performed if the patient has not reacted to a given food on the first day of oral provocation. The guideline discusses various clinical situations for patients with atopic dermatitis to facilitate differentiated diagnostic procedures.

  10. A palavra esgarçada de Giorgio Caproni

    OpenAIRE

    Patricia Peterle

    2014-01-01

    L’esistenza come contraddizione, la perdita, il non-luogo, la storia come verità messa in scacco e la possibilità di lettura dai vestigi trovati negli scavi (della realtà e del linguaggio) sono i temi centrali della poetica di Giorgio Caproni

  11. A palavra esgarçada de Giorgio Caproni

    Directory of Open Access Journals (Sweden)

    Patricia Peterle

    2014-06-01

    Full Text Available L’esistenza come contraddizione, la perdita, il non-luogo, la storia come verità messa in scacco e la possibilità di lettura dai vestigi trovati negli scavi (della realtà e del linguaggio sono i temi centrali della poetica di Giorgio Caproni

  12. Implementing Priority Inheritance Algorithms in an Ada Runtime System

    Science.gov (United States)

    1989-04-01

    Bpp BpBpBpBpBp p:p PjP ^MMVXXXXXXXVXXXXXXXXXM^MJS.XXXXXXXX-j^H^MI^H^VXXXXXXXXXXXXXXXXXXXXXX C2 P P Bp P C2Bp Bp C2 C2 P...B-3: Basic Priority Inheritance Protocol — Example #2 CMU/SEI-89-TR-23 35 • At time f7 , T3 attempts to call server task S3. Because S3 is not

  13. LIBRARY 2.0 TIDAK TERASA ADA DI SEKITAR KITA

    Directory of Open Access Journals (Sweden)

    Rosa Widyawan

    2012-07-01

    Full Text Available This essay reveals application of Web 2.0 tools in some Indonesia university, academic, and special libraries. It is an explorative preliminary study, and this literature based article is a starting effort to conduct a more comprehensive research in this subject. Fifteen library web pages are examined to identify their application of Web 2.0 tools. It finds out that some of them use such tool, but they seem not really aware the advantages of Web 2.0 for their libraries. This essay suggest that the implementation of Web 2.0 tools should be supported by decission makers.

  14. Assessment of the Ada (Trade Name) Validation Process.

    Science.gov (United States)

    1985-12-01

    withdrawn for the above reason; odd that --A wasn’t pre- viously disputed?) CAl011A0, --Al, --A2, --A3, --A4, --A5, -- A6M The test objective should be...reason; odd that --A wasn’t pre- ) viously disputed?] The implementor seems to be correct. I > CA1Ol1AO, --Al. --A2, --A3, --A4, --A5, -- A6M C-5 The

  15. Ada 9X Project Revision Request Report. Supplement 1

    Science.gov (United States)

    1990-01-01

    letters consecutive ordinal order. Currently the EEC is doing a lot of work to merge the independent home markets of its twelve memberstates into one...huge international market . This work is to be completed by 1992. As a consequence there will be applications that need to store or handle information...accessed objects are shared). !discussion 84-01-18 ( DUFT ) As indicated in AI-00004, there is an implementation problem with 9.11(4), in that it always

  16. Mirtel Pohla läheb peatselt tulesurma / Ada Maltseva

    Index Scriptorium Estoniae

    Maltseva, Ada, 1970-

    2007-01-01

    Pirita kloostri varemetes etenduvas Arthur Honeggeri/Paul Claudeli oratooriumis "Jeanne d'Arc tuleriidal", lavastaja Üllar Saaremäe. Näitlejanna reklaamitööst, osalemisest TV3 draamaseriaalis "Kodu keset linna", rollidest filmis ja teatris

  17. Akuntansi Forensik: Perlukah Ada dalam Kurikulum Jurusan Akuntansi?

    Directory of Open Access Journals (Sweden)

    Sugianto

    2014-12-01

    Full Text Available The aim of this study is to identify whether forensic accounting unit should be included in the accounting curriculum of an accounting program at bachelor level. This study employed a discourse analysis approach in understanding the phenomena under investigation. The research result shows that forensic accounting should not be taught as separate course, but it can be incorporated into several accounting course. It is also implied that that education is an essential to produce proper conducts of human as a problem solver in the society and to strengthen the process of developing institutional competencies aimed to prevent fraud and combat corruption.

  18. Test Case Study: Estimating the Cost of Ada Software Development

    Science.gov (United States)

    1989-04-01

    capability of the prograining staff: the section manager, the project manager, and one of the programu- mg staff. Each respondent had a different...ACAP, ECAP , and MDDP new = EKfull + b/0.16 ( E1non - E7full) I __TER ___ VERY VR LWLW NONAL HIGH ACAP 1.57 - 1.29 - 1.00 - 0.80 - 0.61 - 1.46 1.19 1.00

  19. Comparison of the composition of Cinalux amalgam with ADA standard

    Directory of Open Access Journals (Sweden)

    Moosavi Nasab M

    2002-07-01

    Full Text Available Dental amalgam is one of the oldest restorative materials, used in dentistry, which has undergone a lot of quality changes since its advent. Copper is one of the major elements in dental amalgam. Dental amalgam is classified as low and high cooper group based on the percentage of this element. Cinaluy is an Iranian product, a product of Shahid Faghihi's factory and its particles are spherical with high copper and it does not contain any zinc and gama II phase. The goal of this study was to identify the type and percentage of its ingredients and to analyze this dental amalgam by muclear reactor. The products of the factory, at two different times, were compared with each other and also with the percentages presented by the factory, regarding their ingredients. They were also compared with two standardized amalgams called: Sybralloy and Tytin. Three typical Cinalux amalgam capsules, produced on different dates, were selected. The contents of capsules were enveloped in plastic bags and then sealed and placed in a miniature reactor to undergo nuclear radiation for 10 days. After this period, the elements in amalgam became activated and converted into radioisotopes of the same elements, and began to radiate. Then gama spectrometer system accumulated these radiations and transferred them to Span software. This software, aided by reference standards, shows the intensity and the wave length of the received radiation, and consequently identifies the type and percentage of the elements in amalgam. The results demonstrated that the Cinalux amalgam samples, regarding the type and percentage of their elements, were identical and also met the factory standards. The differences were not significant. There was also no significant difference between Cinalux amalgam and the standardized amalgam Sybralloy, regarding the percentage of their elements, but comparing this amalgam with the standardized amalgam Tytin, a significant difference was not observed.

  20. ADAS tools for collisional–radiative modelling of molecules

    Energy Technology Data Exchange (ETDEWEB)

    Guzmán, F., E-mail: francisco.guzman@cea.fr [Department of Physics, University of Strathclyde, Glasgow G4 0NG (United Kingdom); CEA, IRFM, Saint-Paul-lez-Durance 13108 (France); O’Mullane, M.; Summers, H.P. [Department of Physics, University of Strathclyde, Glasgow G4 0NG (United Kingdom)

    2013-07-15

    New theoretical and computational tools for molecular collisional–radiative models are presented. An application to the hydrogen molecule system has been made. At the same time, a structured database has been created where fundamental cross sections and rates for individual processes as well as derived data (effective coefficients) are stored. Relative populations for the vibrational states of the ground electronic state of H{sub 2} are presented and this vibronic resolution model is compared electronic resolution where vibronic transitions are summed over vibrational sub-states. Some new reaction rates are calculated by means of the impact parameter approximation. Computational tools have been developed to automate process and simplify the data assembly. Effective (collisional–radiative) rate coefficients versus temperature and density are presented.

  1. ADAS tools for collisional-radiative modelling of molecules

    Science.gov (United States)

    Guzmán, F.; O'Mullane, M.; Summers, H. P.

    2013-07-01

    New theoretical and computational tools for molecular collisional-radiative models are presented. An application to the hydrogen molecule system has been made. At the same time, a structured database has been created where fundamental cross sections and rates for individual processes as well as derived data (effective coefficients) are stored. Relative populations for the vibrational states of the ground electronic state of H2 are presented and this vibronic resolution model is compared electronic resolution where vibronic transitions are summed over vibrational sub-states. Some new reaction rates are calculated by means of the impact parameter approximation. Computational tools have been developed to automate process and simplify the data assembly. Effective (collisional-radiative) rate coefficients versus temperature and density are presented.

  2. ANTROPOLOGIS TENTANG TRAFFICKING TKW DI MALAYSIA: ANTARA ADA DAN TIADA

    Directory of Open Access Journals (Sweden)

    Tri Marhaeni Pudji Astuti

    2011-12-01

    Full Text Available Trafficking has existed since the period of kingdoms in Java, going on to the colonialism period, andto the present time. Its meaning is broadening beyond human trading into the matters related to violence,blackmailing, and forcing. Trafficking happens not only within one specific area, but has crossed theborder of countries, indicating the existence of an international net. The mushrooming of trafficking isdue to weak law and political commitment of the concerning countries. Moreover, the bilateral talk tobanish trafficking has not been maximally conducted. The actors of trafficking vary from man-powerbrokers, agents, taxi drivers, and even officers (of transmigration and police offices. Trafficking happens invarious places ranging from luxurious spots or starred-hotels to plantations and areas which accommodatea lot of migrants. The victims are usually in so unfavorable bargaining positions that they are muchdependent on those traffickers. This dependency is the impact of imbalanced gender relation. Based onsome existing cases, it is indicated that the women’s lack of power, strength, information, and educationare often misused by the traffickers to take them as their preys. That is why empowering migrant womenis very crucial. One of the ways is empowering them through their realization that this need comes fromtheir own selves, not from any force outside. Besides, there should be strong commitment from the stateto seriously implement the law against any traffickers. Cooperation between the concerning countriesare also needed, for instance by issuing common regulations to banish trafficking.Keywords: Trafficking, migrant women, receiving country, sending country, trafficker

  3. Derivas urbanas: la ciudad extrañada

    Directory of Open Access Journals (Sweden)

    Roger Paez i Blanch

    2014-02-01

    Full Text Available Desde la arquitectura no solo se construyen lugares con acero, madera, hormigón o cristal, sino también con la acción y la mirada. A través de derivas realizadas en distintas ciudades se establecen diferentes maneras de percibir la realidad urbana, maneras que a menudo quedan sepultadas bajo las representaciones dominantes de la ciudad. Construir documentos que muestren la ciudad desde ópticas tangenciales, relacionadas con visiones subjetivas y vivencias concretas, va más allá de un mero ejercicio de representación. Los mapas de derivas urbanas expuestos en este artículo ponen de manifiesto relaciones intensas con la ciudad a través de la acción que resultan en nuevas visiones urbanas. Nuevas maneras de percibir la ciudad abren caminos a nuevos modos de entender la rica realidad urbana, que a su vez inauguran nuevos modos de transformarla desde el proyecto arquitectónico. El sentido último de las derivas presentadas es la de abrirse a la riqueza de la ciudad para descubrir en ella múltiples niveles de sentido que sugieren nuevas maneras de transformar la ciudad

  4. Software Fault Tree Analysis of Concurrent Ada Processes

    Science.gov (United States)

    1994-09-01

    excerpt from the investigation into the Therac -25 accidents: It is clear from the AECL (Atomic Energy of Canada Limited) documentation on the...Publishing Co., Inc., New York, N.Y., 1988 25. Leveson, N.G and Turner, C.S., An Investigation of the Therac -25 Accidents, IEEE Computer, July 1993

  5. ADA Integrated Environment I Computer Program Development Specification. Volume II.

    Science.gov (United States)

    1981-12-01

    APPROVED: JOHN J. MARCINIAK, Colonel, USAF Chief, Command and Control Division FOR THE COMMANDER: -JOHN P. HUSS Acting Chief, Plans Office If your address...Government Documents [N-l IBM Virtual Machine Facility/370: System Programmer Guide, International Buisness Machines, Inc. [N-2] OS/32 Programmer...snapshot of the entire -- database to the tapes mounted by the operator. -- TIMESTAMP is the maximum time sequence number -- of any of the blocks

  6. The Highways and Byways of Teaching ADA: Our Backyard Approach

    Science.gov (United States)

    1994-05-01

    Operaing System Sonureu Hug. "m 0 designpres pw~ihimg w mallr pieces 0 cuwify dined impi. mqsg, flauth weero m mpmg Plow s mots atity Systm adow pm...coorduntiolk anm Syncbrouit (D Potential comntor exacuion of 0D opersutn £rn pocese C room mmkoiztion, F 0occe communication CDExample at th potentially...Aidow.m. I992 0 To ww~am =wm afvbwa My (~PkyucaI ad Wuiffal Mummy Allocation (2 bmsx) VND WtalMmmy M! Device Muanamwa (I bowx) mmmv Q) Dumd Pai 0 Pap Tab

  7. CAPOEIRA: Da senzala às Olimpíadas?

    Directory of Open Access Journals (Sweden)

    Américo Pellegrini Filho

    2010-09-01

    Full Text Available Normal 0 21 false false false PT-BR X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabela normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} Resumo: A partir de meados do século XX, há uma acelerada evolução da Capoeira. De prática de defesa e ataque, originada entre escravos negros no Brasil, passa a jogo atlético e de aprimoramento físico e mental, praticada inclusive por mulheres, sendo, ainda, um item constante em atividades turísticas. A presente análise apresenta como se deu o processo de “embranquecimento” e de valorização da Capoeira, expressas na existência de cerca de 5.500 academias (ou entidades com outras denominações de Capoeira, além da existência de federações nacionais no Brasil, Argentina e Portugal.

  8. Ada Agada African Philosophy and the Challenge of Innovative ...

    African Journals Online (AJOL)

    Oduor

    with certainty to a spontaneous beginning in the causal series. The Big Bang theory of the origin of the universe and the creation theory of Judaism, Christianity and Islam, for example, cannot be practically demonstrated: these theories are speculative. Furthermore, if the universe cannot be accounted for with certainty and if ...

  9. VI Olimpíada Brasileira de Astronomia

    Science.gov (United States)

    Canalle, J. B. G.; Villas da Rocha, J. F.; de Medeiros, J. R.; Wuensche de Souza, C. A.; da Silva, A. R.; Dottori, H. A.; Maia, M. A. G.; Poppe, P. C. R.; Martins, R. V.

    2004-04-01

    In this work we show the results of the VI Brazilian Olympiad of Astronomy, which took place on 17/05/2003 in all primary or secondary schools that previously registered. 76.445 students distributed over 1.565 schools from all Brazilian States took part in this event. A team of 5 students was selected to represent Brazil at the IX International Olympiad of Astronomy (IX IAO) in 2004. We participated of the VIII IAO that occurred in Stockholm, Sweden in 2003. Two of our students were awarded the bronze medal and silver medal in that event.

  10. Christine ja krepid Rakvere ametikoolis / Ada Väät

    Index Scriptorium Estoniae

    Väät, Ada

    2014-01-01

    Lyoni kutsekooli inglise keele õpetaja Christine Crimalault tuli Rakvere ametikooli Erasmuse programmi kaudu. Eestis külastas ta ametikooli tunde, osales kultuuriprogrammis ja kohtus siinsete keeleõpetajatega

  11. Diabetic kidney disease: a report from an ADA Consensus Conference.

    Science.gov (United States)

    Tuttle, Katherine R; Bakris, George L; Bilous, Rudolf W; Chiang, Jane L; de Boer, Ian H; Goldstein-Fuchs, Jordi; Hirsch, Irl B; Kalantar-Zadeh, Kamyar; Narva, Andrew S; Navaneethan, Sankar D; Neumiller, Joshua J; Patel, Uptal D; Ratner, Robert E; Whaley-Connell, Adam T; Molitch, Mark E

    2014-10-01

    The incidence and prevalence of diabetes mellitus have grown significantly throughout the world, due primarily to the increase in type 2 diabetes. This overall increase in the number of people with diabetes has had a major impact on development of diabetic kidney disease (DKD), one of the most frequent complications of both types of diabetes. DKD is the leading cause of end-stage renal disease (ESRD), accounting for approximately 50% of cases in the developed world. Although incidence rates for ESRD attributable to DKD have recently stabilized, these rates continue to rise in high-risk groups such as middle-aged African Americans, Native Americans, and Hispanics. The costs of care for people with DKD are extraordinarily high. In the Medicare population alone, DKD-related expenditures among this mostly older group were nearly $25 billion in 2011. Due to the high human and societal costs, the Consensus Conference on Chronic Kidney Disease and Diabetes was convened by the American Diabetes Association in collaboration with the American Society of Nephrology and the National Kidney Foundation to appraise issues regarding patient management, highlighting current practices and new directions. Major topic areas in DKD included (1) identification and monitoring, (2) cardiovascular disease and management of dyslipidemia, (3) hypertension and use of renin-angiotensin-aldosterone system blockade and mineralocorticoid receptor blockade, (4) glycemia measurement, hypoglycemia, and drug therapies, (5) nutrition and general care in advanced-stage chronic kidney disease, (6) children and adolescents, and (7) multidisciplinary approaches and medical home models for health care delivery. This current state summary and research recommendations are designed to guide advances in care and the generation of new knowledge that will meaningfully improve life for people with DKD. Copyright © 2014 American Diabetes Association and the National Kidney Foundation. Published by Elsevier Inc. All rights reserved.

  12. Ita Ever saab pojalt kingiks filmi / Ada Maltseva

    Index Scriptorium Estoniae

    Maltseva, Ada, 1970-

    2006-01-01

    Näitleja Ita Everi 75-ndaks sünnipäevaks jõuab ekraanile mängufilm "Vana daami visiit" : stsenaristid Roman Baskin, Ilmar Raag : režissöör Roman Baskin : MTÜ Kell Kümme koostöös ETV ja Exitfilmiga, Kultuurkapital. Filmi võtteplatsil toimunust

  13. The Impact of the ADA, 21 Years Later: June 26 Marks the Anniversary of the ADA's Passage

    Science.gov (United States)

    Exceptional Parent, 2011

    2011-01-01

    For most people, their major concern when running errands or shopping is whether they can fit all they need to do into the time available. For people with disabilities, however, particularly for those who have physical disabilities, their major concern is whether they can get into the stores or buildings in the first place and, once in, whether…

  14. Ada (Tradename) Compiler Validation Summary Report. Harris Corporation. Harris Ada Compiler, Version 1.0. Harris HCX-7.

    Science.gov (United States)

    1986-06-12

    range exceeding the INTEGER’LAST values and with a component that is a null BOOLEAN array, this compilar raises NUMERIC ERROR when the type is declared...Computer Systems Division Software Development . Program Structure and Compilation A ’main’ program must be a non-generic subprogram that is either a

  15. Ada (Trade Name) Compiler Validation Summary Report: Irvine Compiler Corporation, ICC Ada Compiler, Release 4.0, Gould 6060

    Science.gov (United States)

    1987-06-29

    resultA demonjicated that the compiler succe’-sfully pass-1 all applicable ’.jts, and that the compilar exhibited the e)pectecl behavior on all...also permitted. 5%’ B-6 Ile -- The following software is the sole property of -- -- Irvine Compiler Corporation -- -- containing its proprietary

  16. Vertebrados terrestres registrados mediante foto-trampeo en arroyos estacionales y cañadas con agua superficial en un hábitat semiárido de Baja California Sur, México Terrestrial vertebrates recorded by camera traps in areas with seasonal streams and creeks of superficial waters in a semiarid habitat of Baja California Sur, Mexico

    Directory of Open Access Journals (Sweden)

    Erika Mesa-Zavala

    2012-03-01

    Full Text Available Los cuerpos de agua superficial (CAS permanentes o efímeros (pozas, tinajas, escurrimientos, etc. que se encuentran en depresiones del terreno, como arroyos y cañadas, son soporte fundamental para el ecosistema en zonas áridas. Mediante el uso de cámaras-trampa, en este estudio se identifican especies de vertebrados terrestres silvestres presentes en 4 sitios con agua superficial, en el extremo sur de la sierra El Mechudo, Baja California Sur, y se analiza el uso de los CAS por las especies en los periodos de actividad. En cada sitio se caracterizó el hábitat (topografía, vegetación y agua. Los 4 sitios mostraron diferencias en sus características ambientales. Se identificaron 41 especies de vertebrados terrestres (3 reptiles, 31 aves y 7 mamíferos. Se encontraron también varias especies de murciélagos que no fueron identificadas. La riqueza de especies y frecuencia de visita fue diferente en cada sitio. Con excepción de 3 especies de mamíferos, el horario de actividad fue similar en los 4 sitios. La presente investigación aporta información sobre la importancia de los CAS en zonas semiáridas, describiendo el hábitat, las especies y su comportamiento, elementos básicos para la conservación y manejo de los recursos naturales.Permanent or ephemeral water ponds (puddles, catchments, drains, and so on located on ground depressions, such as streams and creeks, are a fundamental support for ecosystems in dry areas. This study identified the species of native terrestrial vertebrates in 4 sites in the southernmost part of the Sierra El Mechudo, B.C.S., including how such species use these bodies of water based on the periods of species activity. Habitats were characterized in 4 sites (topography, vegetation, and water sources; camera-traps were placed around water ponds from March to October 2007. The 4 sites differed in their environmental characteristics. Overall, there were 41 species of terrestrial vertebrates (3 reptiles, 31

  17. Revisão integrativa para substituição do soro fetal bovino por plasma humano rico em plaquetas para cultivo e expansão ex vivo de células humanas destinadas às terapias avançadas

    Directory of Open Access Journals (Sweden)

    Karla Menezes

    2018-02-01

    Full Text Available Introdução: O avanço dos ensaios clínicos e da terapia celular implicam na necessidade de substituição do soro fetal bovino por um produto de origem humana, capaz de sustentar a expansão de células humanas destinadas às pesquisas e terapias celulares. Objetivo: Esta revisão integrativa teve como objetivo principal avaliar diferentes alternativas de suplementação de cultura celulares livres de produtos animais, chamadas de culturas celulares xeno-free. Método: Foi realizada a análise de 50 artigos recuperados do PubMed publicados até janeiro de 2018 em língua inglesa ou em português. Resultados: O plasma rico em plaquetas (PRP é considerado como uma boa alternativa para suplementação do meio de cultura celular. O PRP é obtido a partir do sangue, e possui um rico conteúdo liberado pelas plaquetas ativadas, capaz de estimular a proliferação e a diferenciação de diversos tipos de células, tanto diferenciadas quanto progenitoras. A utilização do PRP em sistemas de cultura celular xeno-free não oferece risco de alterações genéticas da população celular, tampouco sua contaminação com patógenos. As vantagens de sua utilização incluem: 1 a possibilidade de uso de soro autólogo; 2 redução de riscos de contaminação; 3 facilidade de preparo e 4 baixo custo de produção. Conclusões: O uso de concentrado de plaquetas descartados nos centros de hemoterapia é uma boa alternativa para a produção do PRP, que será utilizado sistematicamente na cultura de células humanas. O desafio é padronizar esse processo de produção, de forma a garantir a qualidade do produto destinado às terapias avançadas.

  18. Avaliação de mecânica ventilatória por oscilações forçadas: fundamentos e aplicações clínicas Analysis of the ventilatory mechanics by forced oscillations technique: main concepts and clinical applications

    Directory of Open Access Journals (Sweden)

    PEDRO LOPES DE MELO

    2000-08-01

    Full Text Available Requerendo apenas cooperação passiva e fornecendo novos parâmetros para análise da mecânica ventilatória, a técnica de oscilações forçadas (TOF apresenta características complementares aos métodos clássicos de avaliação pulmonar. Neste trabalho, inicialmente é apresentada uma revisão dos princípios da técnica juntamente com uma discussão sobre suas vantagens e atuais limitações. A performance da técnica é comparada com a dos métodos clássicos na detecção de afecções respiratórias. As principais aplicações clínicas reportadas anteriormente na literatura, incluindo a avaliação da mecânica ventilatória infantil, estudos em neonatos, monitorização de pacientes sob ventilação mecânica, medicina ocupacional e avaliação de distúrbios no sono, são revisadas e discutidas. Com base na revisão efetuada e nos resultados obtidos em estudos efetuados em laboratório, os autores concluem que a TOF pode contribuir para um exame mais detalhado, assim como para facilitar a realização de testes de função pulmonar em condições nas quais as técnicas tradicionais não são adequadas.Requesting passive cooperation from the patient and supplying new parameters for the analysis of the ventilatory mechanics, the forced oscillations technique (FOT has complementary characteristics to the classical methods of lung evaluation. In this work, a review of the principles of this technique is initially presented together with a discussion about its advantages and present limitations. The performance of the technique is compared to classical methods in the detection of breathing disorders. The main clinical applications reported previously in the literature, including the evaluation of the ventilatory mechanics in children, studies in neonates, monitoring of patients under mechanical ventilation, occupational medicine, and evaluation of respiratory sleep disturbances are reviewed and discussed. Based on this review and on the

  19. Estudio de la expresividad emocional y la regulación afectiva en díadas madre-bebé durante el primer año de vida y su relación con la autoestima materna Study of emotional expressivity and affective regulation in mother-infant dyads during the first year of life and its relation to maternal self esteem

    Directory of Open Access Journals (Sweden)

    Clara Raznoszczyk de Schejtman

    2005-12-01

    Full Text Available El presente trabajo presenta una articulación entre resultados provenientes de la investigación empírica observacional en díadas madre-bebé y conceptualizaciones psicoanalíticas acerca de la estructuración psíquica. Se recorren conceptos freudianos acerca del rol del auxiliar externo en los primeros tiempos de la vida y especialmente en la constitución de yo. Estos conceptos se ligan a los aportes acerca de la regulación afectiva y el Modelo de Regulación Mutua producidos por los investigadores de infantes. Se filmaron 40 díadas madre bebé y se evaluó la regulación afectiva a través del microanálisis de 3 minutos de interacción cara a cara madre-bebé y 5 minutos de juego libre. Se estudió la autoestima materna a través de una entrevista y de instrumentos autoadministrados. Se presentan los resultados obtenidos acerca de las relaciones entre: la expresividad observada en la madre y el bebé, la expresividad y la autoestima materna y las diferencias obtenidas en las variables según el género de los bebés.The present paper deals with the overlapping between data obtained from observational mother-infant research and psychoanalytical conceptualizations on psychic structure. Freudian concepts, such as the function of the helping external object in the first time of life are presented and specially ego constitution is described. These concepts are linked to the contributions of infant researchers on affective regulation and Mutual Regulation Model. 40 mother-infant dyads were videotaped and affective regulation was studied through the microanalysis of 3 minutes face to face interaction and 5 minutes free play. Maternal self esteem was studied through an interview and self administered instruments offered to the mothers. Results are presented on: the relations obtained between the observed expressivity in the mother and the infant, the relations obtained between Maternal Self Esteem and expressivity and the relation obtained in

  20. Comportamento de variáveis fisiológicas em atletas de nado sincronizado durante uma sessão de treinamento na fase de preparação para as Olimpíadas de Atenas 2004 Comportamiento de variábles fisiológicas en atletas de nado sincronizado durante una sesion de entrenamiento en la fase de preparación para las Olimpíadas de Atenas 2004 Behavior of physiological variables in synchronized swimming athletes during a training session preparing for the Athens 2004 Olympic Games

    Directory of Open Access Journals (Sweden)

    Marina Guimarães Antunes Pazikas

    2005-12-01

    Full Text Available O objetivo do presente estudo foi avaliar o comportamento de variáveis fisiológicas durante uma sessão de treino de nado sincronizado realizada na fase de preparação para as Olimpíadas de Atenas 2004. MATERIAIS E MÉTODOS: A amostra utilizada foi constituída pelo dueto (24 ± 0 anos representante do Brasil em Atenas 2004. A coleta de dados foi realizada durante uma sessão de treinamento com duração de 198 minutos. O treino se iniciou com a parte física, seguida da parte técnica. Para a determinação da glicemia e da concentração de beta-hidroxibutirato foi utilizado o monitor Optium® com suas respectivas tiras. As concentrações de cortisol e das enzimas lactato desidrogenase (LDH e creatina quinase (CK foram determinadas por radioimunoensaio (DPC© e kits comerciais (CELM®, respectivamente. O acompanhamento da freqüência cardíaca (FC foi realizado com o freqüêncimetro Advantage Polar®. RESULTADOS: Foi observada redução (~2% do peso corporal. A glicemia também apresentou queda (~30% em comparação ao valor obtido no início do treino. Em contrapartida, foi observada elevação na concentração de cortisol (salivar 22% e plasmática 29% e de beta-hidroxibutirato (~340%. Não foi observada alteração significativa na concentração plasmática de CK e de LDH. O acompanhamento da FC demonstrou que dos 198 minutos que constituíram a sessão de treino, 36,5 ± 0,7 minutos foram realizados em intensidade leve; 103,5 ± 0,7 minutos em intensidade moderada, 54,0 ± 2,1 minutos em intensidade alta e 4,0 ± 0,0 minutos em intensidade muito alta. CONCLUSÕES: A perda de peso indica que a reposição hídrica não foi adequada. A redução na glicemia e o aumento na concentração de corpos cetônicos e de cortisol reforçam a importância da suplementação de carboidrato durante o treino de longa duração. O comportamento da FC demonstra que a sessão de treinamento foi realizada em uma intensidade moderada, porém com

  1. A prática da evidenciação de informações avançadas e não obrigatórias nas demonstrações contábeis das empresas brasileiras

    Directory of Open Access Journals (Sweden)

    Vera Maria Rodrigues Ponte

    2004-12-01

    Full Text Available Para garantir a qualidade das informações disponibilizadas pelas empresas brasileiras, o legislador e os órgãos de regulamentação têm empreendido esforços no sentido de definir as informações que devem ser apresentadas nas demonstrações contábeis. Entretanto, nem todas as orientações têm caráter de obrigatoriedade, tornando-se mais uma questão de ética e responsabilidade corporativa. O presente estudo procura responder à seguinte questão de pesquisa: Qual o grau de observância às orientações sobre evidenciação contábil praticado pelas sociedades anônimas brasileiras no tocante à prestação de informações não contempladas nas demonstrações contábeis tradicionais, consideradas de natureza avançada e não obrigatória? O estudo analisou as demonstrações contábeis de 95 empresas, relativas ao exercício social encerrado em 31/12/2002, com a utilização do método de "análise de conteúdo". Utilizou-se o software Statistical Package for Social Sciences - SPSS para apoio na tabulação e análise dos dados. De um total de 21 itens de evidenciação investigados, apenas seis apresentaram um índice de observância superior a 50%, o que demonstra que as organizações ainda têm um longo caminho a percorrer na busca da transparência e qualidade na divulgação das informações contábeis.In order to ensure the quality of information issued by Brazilian enterprises, legislators and regulatory agencies are making efforts to determine the set of information that should appear in the financial statements. However, not all of their recommendations are obligatory, turning this into a matter of company ethics and corporate responsibility. In this paper, the authors attempt to answer the following question: To what extent do Brazilian corporations follow the recommendations on advanced and non-obligatory information disclosure, which is not considered in traditional financial statements. Using the content analysis

  2. Efeito do alho (Allium sativum Linn., probiótico e virginiamicina antes, durante e após o estresse induzido pela muda forçada em poedeiras semipesadas Effect of bulb garlic (Allium sativum Linn., probiotic and virginiamycin before, during and after induced forced molt stress in semi-heavily laying hens

    Directory of Open Access Journals (Sweden)

    José Humberto Vilar da Silva

    2003-12-01

    Full Text Available Foram realizados três experimentos com 336 poedeiras no segundo ciclo de produção e 24 meses de idade, alojadas em condições de criação comercial (550 cm²/ave. O objetivo foi avaliar o alho (5 kg/t, probiótico (300 g/t e a virginiamicina (20 g/t como aditivos de rações antes, durante e após o estresse induzido pela muda forçada (MF. O delineamento experimental foi o inteiramente ao acaso e os tratamentos usados foram: dieta controle (DC; DC+alho (A; DC+probiótico (P; DC+virginiamicina (V; DC+A+V; DC+A +P; DC+P+V; DC+A+P+V, constituídos por sete repetições de seis aves. O período pré-experimental foi de 15 dias e o fotoperíodo, de 17 horas de luz/dia. O ensaio 1 foi realizado em quatro semanas antes da MF, com as aves recebendo 110 g de ração contendo os aditivos. O ensaio 2 foi realizado durante os doze dias de MF, com as aves recebendo 10 g de milho moído, usado como veículo para diluir a dose dos aditivos consumida em 110 g de ração. O ensaio 3 foi realizado em seis semanas, durante o terceiro ciclo de produção, com as aves recebendo 110 g de ração, sem os aditivos, e as coletas tiveram início após as aves terem atingido 50% de postura. Antes da MF, o alho reduziu a massa de ovos em relação ao probiótico (48,2 vs. 39,8 g e, durante a MF, a virginiamicina e a mistura P+V reduziram a porcentagem de intestinos em relação ao alho (7,51 e 7,72 vs. 9,43, mas o peso e a porcentagem de baço não foram alterados. Após a MF, as variáveis não foram afetadas pelos tratamentos. Nas condições do experimento, os antimicrobianos usados não melhoram o desempenho de poedeiras antes, durante e após o estresse induzido pela MF em relação à ração sem aditivos.Three trials were carried out with 336 laying hens, aging 24 weeks and after second forced molt, caged in commercial conditions (550 cm²/bird to evaluate the use of bulb garlic (5 kg/t, probiotic (300 g/t and virginiamycin (20 g/t as additives in laying hens

  3. Determinação do limiar anaeróbio em jogadores de futebol com paralisia cerebral e nadadores participantes da paraolimpíada de Sidney 2000 Determination of the anaerobic threshold in soccer players with cerebral palsy and swimmers participant in the Sidney 2000 paralympic games

    Directory of Open Access Journals (Sweden)

    Benedito Sérgio Denadai

    2002-06-01

    Full Text Available Os objetivos desse estudo foram: a determinar o limiar anaeróbio (LAn em jogadores de futebol com paralisia cerebral e nadadores participantes da Paraolimpíada de Sidney 2000 e; b analisar o comportamento do LAn em função das classes dos paratletas. Participaram do estudo, 28 atletas portadores de deficiência, sendo 11 jogadores de futebol com paralisia cerebral (classes: F36, F37 e F38 e 17 nadadores (14 homens e três mulheres (classes: S1 a S10 e B1. Nos jogadores de futebol, o LAn foi determinado em um protocolo progressivo e intermitente na esteira rolante. O LAn foi identificado como sendo a velocidade correspondente a 3,5mM de lactato sanguíneo. Na natação o LAn foi determinado por um protocolo incremental e intermitente de 3 x 200m. Após cada tiro houve coleta de sangue e por interpolação linear, foi calculada a velocidade correspondente a 4mM (LAn. A velocidade aeróbia máxima (Vamax e a correspondente ao LAn apresentaram uma tendência de melhora com o aumento da classe do jogador de futebol com paralisia cerebral. Entretanto, a proporção entre a velocidade do LAn e a Vamax (aproximadamente 80% foi bastante semelhante entre as classes. Na natação, a velocidade correspondente a 4mM aumentou em função do aumento das classes, indicando a limitação da capacidade funcional das classes mais baixas. Por outro lado, as concentrações de lactato em cada percentual da velocidade máxima de 200m foram muito semelhantes entre as classes, e também às obtidas em nadadores não portadores de deficiência. Com base nos resultados obtidos, podemos concluir que a classe (e portanto o nível de deficiência interfere na capacidade funcional aeróbia dos paratletas. Entretanto, a resposta de lactato ao exercício submáximo é semelhante entre as classes e também aos atletas não portadores de deficiência, sugerindo a validade do LAn para a avaliação aeróbia dos nadadores e dos jogadores de futebol com paralisia cerebral

  4. Effect of surface treatments on the bond strength of a zirconia-reinforced ceramic to composite resin Efeito de tratamentos de superfície sobre a resistência de união entre cerâmica reforçada por zircônia e resina composta

    Directory of Open Access Journals (Sweden)

    Alvaro Della Bona

    2007-03-01

    Full Text Available The objective of this study was to evaluate the tensile (sigmat and shear bond strength (sigmas of a glass-infiltrated alumina-based zirconia-reinforced ceramic (IZ - Vita In-Ceram Zirconia to a composite resin, testing the hypothesis that silica coating (SC - Cojet, 3M-Espe produces higher bond strength values than other ceramic surface treatments. Specimens were fabricated and tested according to the manufacturers' instructions, and to ISO6872 and ISO11405 specifications. Sixty IZ disk specimens were polished through 1 µm and divided into 3 groups (n = 20 according to the following surface treatments: HF - 9.5% hydrofluoric acid (Ultradent for 1 min; SB - sandblasting with 25-µm aluminum oxide particles for 10 s; SC - silica coating for 10 s. Silane (3M-Espe, adhesive (Single Bond, 3M-Espe and a composite resin cylinder (Z100, 3M-Espe were applied and polymerized to the treated bonding area (3.5 mm in diameter. Ten specimens from each group (n = 10 were tested for sigmat and ten specimens were tested for sigmas, using a universal testing machine (EMIC DL 2000 at a crosshead speed of 1 mm/min. The data were statistically analyzed by ANOVA and Tukey tests (alpha = 0.05. The mean and standard deviation values (MPa and statistical groupings for sigmat were: HF - 3.5 ± 1.0a; SB - 7.6 ± 1.2b; and SC - 10.4 ± 1.8c. For sigmas, the values were: HF - 10.4 ± 3.1A; SB - 13.9 ± 3.1B; and SC - 21.6 ± 1.7C (p O objetivo deste estudo foi avaliar a resistência adesiva à tração (sigmat e ao cisalhamento (sigmas de uma cerâmica à base de alumina infiltrada por vidro e reforçada com zircônia (IZ- Vita In-Ceram Zircônia à resina composta, testando a hipótese de que o sistema de silicatização (SC- Cojet, 3M-ESPE produz valores maiores de resistência adesiva do que demais tratamentos de superfície utilizados. Sessenta corpos-de-prova (cp em forma de disco da IZ foram fabricados e testados de acordo com as instruções dos fabricantes e as

  5. Resultados obtidos em mulheres portadoras de endometriose pélvica avançada e mulheres com ligadura tubária, submetidas a ICSI: análise comparativa Outcome of women with advanced pelvic endometriosis and women with tubal sterilization submitted to ICSI: a comparative analysis

    Directory of Open Access Journals (Sweden)

    Tsutomu Aoki

    2005-10-01

    Full Text Available OBJETIVO: análise comparativa dos resultados obtidos em mulheres portadoras de endometriose pélvica avançada e mulheres com ligadura tubária, submetidas a injeção intracitoplasmática de espermatozóide (ICSI. MÉTODOS: noventa e três mulheres com diagnóstico de infertilidade, com ciclo menstrual normal, não submetidas a qualquer tratamento hormonal e cirúrgico durante o último ano, índice de massa corporal igual a 20-25, portadoras de ovários sem a presença de cistos ou tumores participaram deste estudo e foram divididas em dois grupos: tubário (TUB, 39 mulheres com ligadura tubária, e endometriose (EDT, 54 mulheres com EDT-III e EDT-IV, submetidas a indução ovulatória com FSH-r e ICSI. Os dados clínicos e laboratoriais foram comparados. Testes chi2, Fisher, t pareado, t de Student e Mann-Whitney foram empregados. RESULTADOS: níveis mais baixos de estradiol (2243,1 vs 1666,3; p=0,001 e número menor de folículos por paciente (16,9 vs 13,9; p=0,001 foram recuperados no grupo EDT, apesar da utilização de maior número de unidades de FSH-r (1775,6 vs 1998,6; p=0,007, para TUB e EDT, respectivamente. Não houve diferença quanto à taxa de recuperação ovocitária (69 vs 73,5%; p=0,071 assim como nas taxas de fertilização normal (83,7 vs 81,7%; p=0,563 respectivamente para TUB e EDT. No entanto, menor número de pré-embriões ótimos foi obtido no grupo EDT (36,4 vs 24,8%, respectivamente para TUB e EDT; p=0,005. As taxas de gestação total (41,0 vs 42,6%; p=0,950 e de implantação (13,9% x 14,5%; p=0,905 não foram significativamente diferentes quando TUB e EDT foram comparados. CONCLUSÕES: os ovários das mulheres do grupo EDT parecem ser menos responsivos à indução da ovulação com FSH-r. A endometriose parece comprometer o número médio de folículos e de pré-embriões ótimos sem prejudicar as taxas de recuperação ovocitária e fertilização. No entanto, uma vez formados, os pré-embriões do grupo EDT

  6. Validação de novos valores previstos brasileiros para a espirometria forçada na raça branca e comparação com os valores previstos obtidos por outras equações de referência Validation of new brazilian predicted values for forced spirometry in caucasians and comparison with predicted values obtained using other reference equations

    Directory of Open Access Journals (Sweden)

    Andrezza Araújo de Oliveira Duarte

    2007-10-01

    Full Text Available OBJETIVO: Comparar os novos valores previstos brasileiros de capacidade vital forçada e volume expiratório forçado no primeiro segundo para a espirometria obtidos em 2006 com os obtidos por outras equações de referência e validar os achados por meio da comparação com uma nova amostra de brasileiros normais. MÉTODOS: Realizou-se espirometria forçada, de acordo com as normas da Sociedade Brasileira de Pneumologia e Tisiologia, em 643 adultos brancos não-fumantes. Os valores previstos obtidos por pesquisadores brasileiros em 1992 e os obtidos por quatro grupos de pesquisadores estrangeiros foram comparados com os novos valores previstos brasileiros obtidos em 2006. Em uma segunda fase, os valores médios obtidos em 65 mulheres e 79 homens adultos foram comparados aos valores previstos obtidos pelas diversas equações de referência. RESULTADOS: O teste t para amostras pareadas revelou diferenças significativas entre os valores previstos obtidos pelas seis equações e os obtidos pela equação brasileira de 2006. Na segunda fase, observou-se que os valores previstos obtidos por Crapo et al. e os obtidos por Hankinson et al. para os méxico-americanos mostraram valores médios semelhantes aos observados na nova amostra. Porém, quando os valores previstos obtidos na nova amostra foram comparados com os obtidos por esses autores, discrepâncias foram observadas, com valores previstos altos e baixos. Os valores obtidos pela equação brasileira de 2006 mostraram as menores diferenças em comparação com os valores médios obtidos na nova amostra. CONCLUSÕES: Estes resultados sublinham a importância de se usar equações de predição para espirometria que sejam apropriadas para nossa população.OBJECTIVE: To compare the most recent (2006 predicted values of forced vital capacity and forced expiratory volume in one second for spirometry in Brazilians with those obtained using other reference equations and to validate the findings

  7. Aves endêmicas e ameaçadas de extinção da Estação Ecológica de Xitué e a contribuição do taquaruçu Guadua tagoara (Nees Kunth para a riqueza local. Endemic and threatened birds of the Xitué Ecological Station and the contribution of the bamboo Guadua tagoara (Nees Kunth to local richness.

    Directory of Open Access Journals (Sweden)

    Alexsander Zamorano ANTUNES

    2007-12-01

    Full Text Available O contínuo ecológico da Serra deParanapiacaba, no sul do Estado de São Paulo,é uma área de extrema importância para aconservação das aves. Dentro do contínuo, a EstaçãoEcológica de Xitué é a Unidade de Conservaçãocuja avifauna é menos conhecida. Em levantamentoefetuado em 2006 foram registradas em Xitué48 espécies endêmicas da Mata Atlântica e 8ameaçadas de extinção. Apesar de ser a espécievegetal dominante em vastos trechos da estação,o taquaruçu Guadua tagoara (Nees Kunth parececontribuir pouco para a riqueza de espécies de avesencontradas. No entanto, entre estas espécies seencontra o criticamente ameaçado papa-capim-dataquaraSporophila falcirostris, granívoroespecializado em sementes de taquaras.The Paranapiacaba Range ecologicalcontinuum, in State of São Paulo southernBrazil, is an extremely important area to birdconservation. In Paranapiacaba Range the birds ofXitué Ecological Station remains poorly known.We surveyed the Xitué birds in 2006 and we found48 Atlantic Forest endemics species and 8 threatened.Although the bamboo Guadua tagoara (NeesKunth dominate many areas of Xitué, it contributedtoo little for bird richness. However, between thesebird species was the critically endangered Temminck’sSeedeater Sporophila falcirostris, specializedbamboo granivorous.

  8. Ada (Trade Name) Compiler Validation Summary Report: Irvine Compiler Corporation. ICC Ada Compiler, Release 4.0, VAX-11/750.

    Science.gov (United States)

    1988-06-27

    was submitted to the AVF by the applicant for review. naL .I .i of these resuiA.j demoitrated that the compilar successfully Dassed all applicable...types or unconstrained strings. Default values are also permitted. B-6 -- The following software is the sole property of -- -- Irvine Compiler

  9. DOE hearing on the draft area recommendation report for the Crystalline Repository Project, Ada High School Gymnasium, Ada, Minnesota, April 3, 1986: Transcript of proceedings

    International Nuclear Information System (INIS)

    1986-01-01

    This document contains a transcript of the comments of 64 witnesses. These meetings were held to hear public comments regarding the selection of a site for a second high-level nuclear waste repository

  10. Ada (Trade Name) Compiler Validation Summary Report: Verdix Ada Compiler System (VAda-010-0101) Version 6.0, VAX-11/750.

    Science.gov (United States)

    1986-04-02

    camot be my of dw following: a loop variable, a constant, an initalized variable, an aray, or a record& 2. Iuplementadom of Predeflued Prngan 2.1...not suppord L Restriction o Usicbecked Conversma The predefined gearic funco UNCHECKED CONVERSION camot be instanuated with a target type which is a

  11. DOE hearing on the draft area recommendation report for the Crystalline Repository Project, Ada High School Gymnasium, Ada, Minnesota, April 3, 1986: Transcript of proceedings

    International Nuclear Information System (INIS)

    1986-01-01

    This document contains a transcript of the comments of 64 witnesses. These meetings were held to hear the public's comments regarding the selection of a site for a second high-level radioactive waste repository

  12. Avaliação do padrão e das queixas relativas ao sono, cronotipo e adaptação ao fuso horário dos atletas brasileiros participantes da paraolimpíada em Sidney - 2000 Evaluation of sleep patterns and sleep-related complaints, chronotype, and time zone adaptation of Brazilian athletes participant in the Sydney 2000 paralympic games

    Directory of Open Access Journals (Sweden)

    Marco Túlio de Mello

    2002-06-01

    Full Text Available Diversas metodologias têm sido desenvolvidas para investigar a qualidade e as principais queixas e distúrbios relacionados ao sono. Uma forma conhecida de investigar as características temporais dos organismos é a cronobiologia, ciência divide a população em três cronotipos básicos para avaliar as diferenças individuais na prevalência pelos horários de vigília e de sono: os matutinos, os vespertinos e os indiferentes. Outro ponto importante, é que existem poucos estudos relacionando o padrão do sono em indivíduos com necessidades especiais e a atividade física. O sono é considerado como restaurador e o exercício está associado diversas alterações no padrão de sono. A maioria dos estudos referente ao feito do exercício sobre o sono podem ser abordados ou correlacionados com a teoria de restauração das funções do sono. O objetivo deste estudo foi o de avaliar o padrão, queixas relativas ao sono, cronotipo e adaptação ao fuso horário de Sidney dos atletas brasileiros que disputaram a paraolimpíada em 2000. Participaram da avaliação 64 atletas paraolímpicos, com idades de 26,3 (± 5,9. Todos os atletas responderam aos questionários de padrão e queixas relativas ao sono e cronotipo, passando também por uma adaptação ao fuso horário de Sidney. Oprocesso de sincronização ao fuso horário foi realizado de forma abrupta, na tentativa de romper com o ciclo claro-escuro que estava relacionado ao horário brasileiro. Os resultados demonstram que 34,4% dos atletas apresentavam uma insatisfação com o seu próprio sono, sendo que os distúrbios de sono mais relatados foram: apnéia (14%, refluxo gástrico (15,6%, dor de cabeça (14,1%, ansiedade pós-pesadelo (39,1%, caimbras (20,3%, sonilóquio (26,6%, pânico noturno (9,4%, PLM (9,4% e bruxismo (9,4%. Em relação a avaliação do cronotipo dos atletas, 73,43% se demonstraram indiferentes, 6,22% vespertinos moderados e 20,31% matutinos moderados. Observou-se boa

  13. Cerâmicas avançadas no processo de retificação cilíndrica externa de mergulho com rebolos diamantados com a técnica da mímima quantidade de lubrificação e refrigeração otimizada Advanced ceramics in the external cylindrical plunge grinding using the technique of minimum quantity of lubrication and the technique of optimized refrigeration with diamond wheels

    Directory of Open Access Journals (Sweden)

    M. H. Oikawa

    2011-09-01

    Full Text Available Os materiais cerâmicos têm muitas vantagens em relação a outros materiais, entre elas, três principais: capacidade de operação em altas temperaturas, alta dureza e alta resistência ao desgaste. Por essa razão, são aptos a serem usados em situações que exigem pouco desgaste, tanto em temperatura ambiente quanto em temperaturas elevadas. Estas propriedades fizeram as cerâmicas avançadas terem uma importante parte na utilização em aplicações na indústria nas últimas décadas. Porém, o custo agregado ao acabamento da peça ainda é muito alto. Esse acabamento geralmente é feito pelo processo de retificação, único processo economicamente viável que produz superfícies de elevada qualidade e precisão geométrica. As empresas desse modo vêm buscando a otimização no processo de retificação de cerâmicas, explorando outras técnicas de lubrificação. Assim, este projeto pretendeu explorar a otimização do método de lubrificação na retificação cilíndrica externa de mergulho com o método da mínima quantidade de lubrificação (MQL e refrigeração otimizada. Foram utilizadas três métodos de refrigeração, o convencional o MQL e a refrigeração otimizada, com três avanços de corte para cada caso. Foram analisadas como variáveis de saída a relação G, rugosidade e circularidade. Dos resultados obtidos, pode-se concluir que a refrigeração otimizada é a que apresenta os melhores resultados, sendo esta uma alternativa viável de melhora do processo. O MQL apresentou resultados insatisfatórios em comparação aos outros dois métodos, porém, ainda aceitáveis em alguns processos de retificação. Considerando a dificuldade e altos custos de descarte do fluido de corte devido às rígidas leis ambientais, o MQL vem como uma forte tendência neste tipo de processo.Ceramic materials have many advantages over other materials, including three main: capability of operating at high temperatures, high hardness and

  14. Birgy Lorenz julgustab nutiseadmeid hariduse heaks tööle rakendama / Ada Maltseva

    Index Scriptorium Estoniae

    Maltseva, Ada, 1970-

    2016-01-01

    Vestlusest algatuse "Nutitund igasse kooli!" eestvedaja, Tallinna Pelgulinna gümnaasiumi IT-arendusjuhi ja õpetaja Birgy Lorenziga nutitunni projektist. Ta on Eesti informaatikaõpetajate seltsi juhatuse liige, Tallinna ülikooli lektor nuti- ja digiturbe alal ning ka sealse digiturbe labori projektijuht. Netiturvalisust uurib ta oma doktoritöös "Teismelise internetikasutaja turvastrateegiad"

  15. PEDALAR NA COPA 2014 E NAS OLIMPÍADAS 2016 NO BRASIL?

    Directory of Open Access Journals (Sweden)

    Rodrigo Duarte Ferrari

    2010-10-01

    Full Text Available This paper is an approximation tothe projects of the FIFA World Cupin 2014 and 2016 Olympic Gamesto be held in Brazil. The intentionof the study is describing what isprovided in the projects of these twoevents in relation to urban mobility,as well as examinating these proposalsfrom the perspective of thepromotion and consolidation of thebicycle as a mobility alternative. Fordoing this the following topics arepresented: The Bicycle Brazil Project:Achievements and Challenges,which is a national public policyproposition of using the bicycle as amobility option; the Urban Mobilityproject of the World Cup host cities in 2014; and the Rio de Janeiro´ sUrban Mobility project for the 2016Olympics. Finally, after presentingthe three projects, they are articulatedwith emphasis on educationalopportunities and cultural formation,concluding that the bicycle as ameans of transport is almost ignoredin all dimensions as an alternative ofUrban Mobility in these events heldin Brazil.

  16. De Ada Byron a Grace Hopper y las programadoras del ENIAC: los bits, en femenino

    OpenAIRE

    Molero Prieto, Xavier

    2015-01-01

    Las mujeres han desempeñado, y lo siguen haciendo, un papel destacado en el desarrollo de la informática. Aunque ha sido tradicionalmente poco destacada, su contribución fue determinante en dos momentos históricos muy importantes. Primero, durante la génesis, ya a mediados del siglo XIX, de la idea de computador y, segundo, tras acabar la segunda guerra mundial una centuria después, cuando la informática hace acto de aparición en la sociedad ligada a la tecnología electrónica. En este trabajo...

  17. 300 Spanish in Sub-Saharan Africa: Whither Nigeria? Purity Ada ...

    African Journals Online (AJOL)

    Tracie1

    Abstract. The apparent lack of recognition of the need for Spanish as a foreign language is surprising in Nigeria where only one federal university offers Spanish (Uchechukwu, 2014). Even the Spanish government's Action Plans for Africa (2001-2012), efforts at the diplomatic level to foster bilateral relationships through ...

  18. The first colliders: AdA, VEP-1 and Princeton-Stanford

    Energy Technology Data Exchange (ETDEWEB)

    Shiltsev, V. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2013-07-11

    The idea of exploring collisions in the center-of-mass system to fully exploit the energy of the accelerated particles had been given serious consideration by the Norwegian engineer and inventor Rolf Wideröe, who had applied for a patent on the idea in 1943 (and got the patent in 1953 [1]) after considering the kinematic advantage of keeping the center of mass at rest to produce larger momentum transfers. Describing this advantage G.K.O’Neill, one of the collider pioneers, wrote in 1956 [2]: “…as accelerators of higher and higher energy are built, their usefulness is limited by the fact that the energy available for creating new particles is measured in the center-of-mass system of the target nucleon and the bombarding particle. In the relativistic limit, this energy rises only as the square root of the accelerator energy. However, if two particles of equal energy traveling in opposite directions could be made to collide, the available energy would be twice the whole energy of one particle...” Therefore, no kinetic energy is wasted by the motion of the center of mass of the system, and the available reaction energy ER = 2Ebeam (while a particle with the same energy Ebeam colliding with another particle of the mass m at rest produces only ER = (2Ebeam m)½ in the extreme relativistic case.) One can also add that the colliders are “cleaner” machines with respect to the fixed target ones since the colliding beams do not interact with the target materials. The other advantage is that it is much easier to organize collisions of beams composed of matter-antimatter particles, like in electron-positron and proton-antiproton colliders.

  19. PENGARUH HUMAN CAPITAL TERHADAP KINERJA AUDITOR PADA KAP YANG ADA DI BANDUNG

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    Nono Supriatna

    2014-04-01

    Full Text Available This research starting from the professionalism accountants as human capital at accountant firm as a service company. This research is intended  to study the effect of human capital on auditor performance at KAP in Bandung to propose the hypothesis that human capital has positive influence on auditors performance, either partially or simultaneously. Some dimensions of the sub-variables that make up the human capital that will be studied is represented by the factors individual capability, individual motivation, leadership, the organizational climate, and workgroup effectiveness. The auditor’s performance is measured by three factors that make up the performance:  (1 individual factor, (2 psychology factor, and (3 organization factor.             The research was conducted at the accounting firm located in Bandung. Of the number of samples taken at random population consisting of senior accountants and junior accountants as respondents. Technique of data collecting used  questionnaire. In accordance with the measurement scale, the data has been collected tested the validity of the formula Spearman Rank correlation and reliability with Cronbach alpha. The data has been tested and found valid and reliable then analyzed by correlation and regression analysis.             Based on the results of correlation and regression analysis to test hypotheses derived research findings that human capital simultaneously has a fairly close relationship with performance. While the multiple regression analysis known that each dimension contributes to the performance of the auditor's diverse and significant at p = 0.05, so the significance of test results, either partially or simultaneously can be concluded to accept the research hypothesis, namely human capital has positive influence on the performance of auditors.

  20. CURRÍCULO EM TEMPOS DE ESCOLA SEM PARTIDO: hegemonia disfarçada de neutralidade

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    Graça Regina Franco da Silva Reis

    2016-09-01

    Full Text Available O presente texto promove um diálogo entre o que intenta a Proposta de Lei Escola Sem Partido (que visa combater o que chama de doutrinação ideológica nas escolas e universidades com as noções que vêm sendo tecidas pelo campo de estudos do currículo. Ao trazermos a compreensão dos currículos como criação cotidiana, dos professorxs e alunxs como autores dos seus processos de ensinoaprendizagem e da produção do conhecimento como tessitura em rede evidencia-se que um currículo neutro, não ideológico e apolítico é impraticável, assim como é impossível que os professorxs aprendam a separar seus valores morais, políticos e ideológicos dos conteúdos, pois nem mesmo os conteúdos escolares previstos nos currículos formais o são. Além da discussão epistemológica, são trazidas narrativas docentes como um recurso que nos ajuda a compreender a indissociabilidade entre as múltiplas dimensões (fazer/sentir/pensar das quais está embebida a prática docente. Diante de tal impossibilidade percebemos que aqueles que promovem a ideia de uma escola neutra, ou possuem uma ingenuidade político-epistemológica ou, na verdade, maquiam um projeto de Escola de Um Único Partido: o hegemônico, que toma como verdade absoluta os conhecimentos validados pela alta cultura e, portanto, não relativiza o status quo. Concluímos que, em qualquer uma dessas possibilidades, devemos combater o projeto Escola Sem Partido assegurando o respeito mútuo e a expressão efetiva do direito à diferença nas nossas políticas curriculares educacionais, pois lecionar por um projeto de cidadania não pode ser crime!