WorldWideScience

Sample records for activity programme establishing

  1. Establishing a national universal vaccination programme.

    Science.gov (United States)

    Duma, R

    1995-01-01

    The collaborative efforts of healthcare providers, governmental policy and law makers and the public are often needed to provide the pressure necessary to establish a national universal vaccination programme. Key initiatives for those beginning to establish such a programme are the following: secure a scientific consensus or base of support; clarify relevance of the subject to all concerned; increase awareness of everyone (providers and consumers); recruit and involve influential people (angels) for support; seek out agendas within which to review the topic; generate cost-benefit data; encourage a consensus to be reached; identify legislative pathways to be used; convince politicians of the value of such a programme; request budgeting and funding; and, finally, follow up with surveillance studies to demonstrate the benefits of the programme.

  2. Establishing a Professional Identity via Mentoring in Design Programmes

    DEFF Research Database (Denmark)

    Bennyson, René; Hansen, Birgitte Kjølner; Blond, Malene

    2016-01-01

    the student’s job entry in the industry as opposed to professional mentoring within the industry where professionals mentor professionals for career development In conclusion this article is seeking to present an example of how a student becomes aware of a professional identity by being a legitimate......The use of a mentor mentee relation in the course of a not well known design programme in Bachelor of Applied Science will strengthen the establishment of the student’s professional identity, with the overall purpose of the student positioning themselves as a professional. The relation...... to the establishment of a professional identity for the student. The mentor mentee meetings is facilitated through a series of activities throughout the educational programme. The Activities arising from categories of practice, social relation and professional environment, which encapsulate the creation...

  3. Microarray of programmable electrochemically active elements

    DEFF Research Database (Denmark)

    McCaskill, John; Maeke, Thomas; Straczek, Lukas

    Possible applications of the MICREAgents Dock, a two dimensional array of programmable electrochemically active elements, to Alife.......Possible applications of the MICREAgents Dock, a two dimensional array of programmable electrochemically active elements, to Alife....

  4. Establishing a pharmacotherapy induced ototoxicity programme within a service-learning approach

    Directory of Open Access Journals (Sweden)

    Natalie Schellack

    2015-02-01

    Full Text Available Pharmacotherapy-induced ototoxicity is growing, especially in developing countries such as South Africa. This highlights the importance of ototoxicity monitoring and management of hearing loss. This article focuses on the establishment of an ototoxicity clinic as a site for the implementation of a service-learning module in the Audiology programme. The clinic offers a unique opportunity of collaboration between pharmacists and an audiologist where pharmacotherapy-induced ototoxicity is uniquely monitored. The Sefako Makgatho Health Sciences University (SMU provides training to both the disciplines audiology and pharmacy. The main aim of this article is to describe how ototoxicity monitoring is implemented in the curriculum within such an academic service-learning approach. Through service learning students develop a deeper understanding of course content, acquire new knowledge and engage in civic activity. It simultaneously provides a unique opportunity for interdisciplinary collaboration between the disciplines of audiology and pharmacy. The objectives for this programme are therefore to facilitate learning and to provide a service to the local community by identifying, preventing and monitoring medicine-induced hearing loss in in-hospital and out-patients; as well as to establish inter-disciplinary collaboration between the disciplines and stakeholders for more effective service delivery. The constant interdisciplinary teamwork between the audiologist, pharmacist, physician and nursing staff in the wards results in best practice and management of patients with ototoxic damage.

  5. Establishing a pharmacotherapy induced ototoxicity programme within a service-learning approach.

    Science.gov (United States)

    Schellack, Natalie; Wium, Anna M; Ehlert, Katerina; van Aswegen, Yolande; Gous, Andries

    2015-06-17

    Pharmacotherapy-induced ototoxicity is growing, especially in developing countries such as South Africa. This highlights the importance of ototoxicity monitoring and management of hearing loss. This article focuses on the establishment of an ototoxicity clinic as a site for the implementation of a service-learning module in the Audiology programme. The clinic offers a unique opportunity of collaboration between pharmacists and an audiologist where pharmacotherapy-induced ototoxicity is uniquely monitored. The Sefako Makgatho Health Sciences University (SMU) provides training to both the disciplines, audiology and pharmacy. The main aim of this article is to describe how ototoxicity monitoring is implemented in the curriculum within such an academic service-learning approach. Through service learning students develop a deeper understanding of course content, acquire new knowledge and engage in civic activity. It simultaneously provides a unique opportunity for interdisciplinary collaboration between the disciplines of audiology and pharmacy. The objectives for this programme are therefore to facilitate learning and to provide a service to the local community by identifying, preventing and monitoring medicine-induced hearing loss in in-hospital and out-patients; as well as to establish inter-disciplinary collaboration between the disciplines and stakeholders for more effective service delivery. The constant interdisciplinary teamwork between the audiologist, pharmacist, physician and nursing staff in the wards results in best practice and management of patients with ototoxic damage.

  6. Establishing a method to support academic and professional competence throughout an undergraduate radiography programme

    Energy Technology Data Exchange (ETDEWEB)

    Ng, Curtise K.C. [Department of Health Technology and Informatics, Hong Kong Polytechnic University, Hung Hom, Kowloon (Hong Kong)], E-mail: or.curtis@polyu.edu.hk; White, Peter [Department of Health Technology and Informatics, Hong Kong Polytechnic University, Hung Hom, Kowloon (Hong Kong)], E-mail: htpwhite@polyu.edu.hk; McKay, Janice C. [Department of Health Technology and Informatics, Hong Kong Polytechnic University, Hung Hom, Kowloon (Hong Kong)], E-mail: htjanmck@polyu.edu.hk

    2008-08-15

    Purpose: Radiography degree programmes are coming under increasing pressure from the community to ensure that graduates have not only the necessary academic development but also the practice-based skills. This study aims to establish a method of monitoring students' progress towards, and ability to meet, academic and professional competences throughout a radiography programme. Methods: Questionnaires were designed for students and academic staff to determine the stages and standards of progress of competence development, and to inform the review process of the current assessment tools throughout the programme. A literature search identified the appropriate pedagogy as a basis for devising the method. Another questionnaire was distributed to overseas radiography institutions to gain insights into other assessment practices to validate the framework. Results and discussion: It was established that years of study rather than semester periods were appropriate to allow students to meet the standards. Discrepancies were noted in the expectations between academic staff (higher expectations) and students (more realistic) in terms of the pace of development expected. As students progress at different rates, and do not experience the same clinical exposure, their ability to meet expectations may differ and so both sets of expectations were combined as a range of criteria. A multi-dimensional assessment approach should be adequate to gauge students' progress but time and resource effectiveness has not yet been addressed. The portfolio was identified as the pedagogy capable of integrating all the competence assessment tools, linked by reflective writing, to gather individual outcomes into a whole, and form a holistic framework. Outcome: The portfolio framework will initially run as a voluntary activity and standards of progress corresponding to the students' stages will be delivered to participants in advance. Participants will be required to select materials

  7. Microarray of programmable electrochemically active elements

    DEFF Research Database (Denmark)

    S. McCaskill, John; Maeke, Thomas; Straczek, Lukas;

    2016-01-01

    This paper describes possible applications of a two dimensional array of programmable electrochemically active elements to Alife. The array has been developed as part of the MICREA-gents project, and after several design phases, is now a mature enough device for general use beyond the project. Here...

  8. Microarray of programmable electrochemically active elements

    DEFF Research Database (Denmark)

    S. McCaskill, John; Maeke, Thomas; Straczek, Lukas

    2016-01-01

    This paper describes possible applications of a two dimensional array of programmable electrochemically active elements to Alife. The array has been developed as part of the MICREA-gents project, and after several design phases, is now a mature enough device for general use beyond the project. Here...

  9. Diversity Programme Activity Report 2012-2015

    CERN Document Server

    Guinot, Genevieve; CERN. Geneva. HR Department

    2016-01-01

    CERN’s Diversity programme was launched in 2012 and is now firmly established as one of the pillars of the Organization’s Human Resources strategy. This report provides information on the actions undertaken in pursuit of the seven diversity strategic objectives set for the period from 2012 to 2015 in the priority areas identified for actions of recruitment, career development and work environment. The report highlights the progress made in anchoring the diversity principles in policies, procedures and practices within the Organization, as well as the persistent difficulties for the Organization to improve the representation of some nationalities and to attract female applicants in science and engineering. It shows a constant increase of female representation in managerial positions and encouraging results in building a diverse talent pool of scientists and engineers through the various student and graduate programmes. The report also outlines how the Diversity Office contributed through several actions,...

  10. Establishing a Korean Language Programme in a European Higher Education Context: Rationale, Curriculum and Assessment Procedures

    Science.gov (United States)

    Carson, Lorna; Do, Eunjee

    2013-01-01

    A growth in interest in Korean contemporary culture in Europe has benefitted Korean language studies in Higher Education. This article describes an innovative Korean language programme in the School of Linguistic, Speech and Communication Sciences at Trinity College Dublin, Ireland. Since its establishment as a pilot project in 2010, the Korean…

  11. Establishing a Korean Language Programme in a European Higher Education Context: Rationale, Curriculum and Assessment Procedures

    Science.gov (United States)

    Carson, Lorna; Do, Eunjee

    2013-01-01

    A growth in interest in Korean contemporary culture in Europe has benefitted Korean language studies in Higher Education. This article describes an innovative Korean language programme in the School of Linguistic, Speech and Communication Sciences at Trinity College Dublin, Ireland. Since its establishment as a pilot project in 2010, the Korean…

  12. Establishing an independent mobile health programme for chronic disease self-management support in Bolivia

    Directory of Open Access Journals (Sweden)

    John D Piette

    2014-08-01

    Full Text Available Background: Mobile health (m-health work in low and middle-income countries (LMICs mainly consists of pilot programmes with an unclear path to scaling and dissemination. We describe the deployment and testing of an m-health platform for non-communicable disease (NCD self-management support in Bolivia. Methods: 364 primary care patients in La Paz with diabetes or hypertension completed surveys about their use of mobile phones, health and access to care. 165 of those patients then participated in a 12-week demonstration of automated telephone monitoring and self-management support. Weekly Interactive Voice Response (IVR calls were made from a platform established at a university in La Paz, under the direction of the regional health ministry. Results: 37% of survey respondents spoke indigenous languages at home, and 38% had six or fewer years of education. 82% had a mobile phone; half (45% used text messaging with a standard phone, and 9% had a smartphone. Smartphones were least common among patients who were older, spoke indigenous languages, or had less education. IVR programme participants completed 1007 self-management support calls, with an overall response rate of 51%. IVR call completion was lower among older adults, but was not related to patients’ ethnicity, health status or healthcare access. IVR health and self-care reports were consistent with information reported during baseline interviews. Patients’ likelihood of reporting excellent, very good, or good health (versus fair or poor health via IVR increased during programme participation, and was associated with better medication adherence. Patients completing follow-up interviews were satisfied with the programme, with 19/20 (95% reporting that they would recommend it to a friend. Conclusions: By collaborating with LMICs, m-health programmes can be transferred from higher-resource centres to LMICs and implemented in ways that improve access to self-management support among people

  13. An Irish Experience in Establishing and Evaluating an Intern Led Teaching Programme.

    Science.gov (United States)

    Jenkinson, A; Kelleher, E; Moneley, D; Offiah, G

    2017-03-10

    Near-Peer Teaching is a relatively new and expanding area of medical education. The benefit to medical students has been demonstrated in numerous contexts around the world. Our aim was to establish a structured Intern-Led Teaching (ILT) programme in the context of an Irish Intern Training Network affiliated to an Irish Medical School. We then sought to evaluate the success of this programme. Seventy interns were enrolled in the ILT programme and completed a Train the Trainer course involving teaching methods and skills of effective feedback. Following this, the intern tutors delivered several one-hour teaching sessions in small groups to final year medical students on a weekly basis. At the end of each teaching block, a feedback questionnaire was distributed to participating students to evaluate their experiences of this new teaching modality. Tutorial topics were varied. They included clinical examination, history taking, prescribing, and emergencies. Eighty-one percent of students found the intern-led tutorials to be beneficial compared to tutorials run by more senior doctors. Additionally, students felt that with intern led tutorials they could ask questions they otherwise would not. There was a more comfortable environment, and information taught was considered more relevant. A significant number of students felt less nervous about the final medical examinations after the intern-led tutorials. The establishment of a structured intern-led teaching programme was well received by final year medical students. This project shows that interns are a valuable teaching resource in the medical school and should be included in medical schools' curricula.

  14. Characterization of the plastid-specific germination and seedling establishment transcriptional programme.

    Science.gov (United States)

    Demarsy, E; Buhr, F; Lambert, E; Lerbs-Mache, S

    2012-01-01

    Upon imbibition, dry seeds rapidly gain metabolic activity and the switching on of a germination-specific transcriptional programme in the nucleus goes ahead, with the induction of many nucleus-encoded transcripts coding for plastid-localized proteins. Dedifferentiated plastids present in dry seeds differentiate into chloroplasts in cotyledons and into amyloplasts in the root and in the hypocotyl, raising the question of whether the beginning of a new plant's life cycle is also characterized by specific changes in the plastid transcriptional programme. Here the plastid transcriptome is characterized during imbibition/stratification, germination, and early seedling outgrowth. It is shown that each of these three developmental steps is characterized by specific changes in the transcriptome profile, due to differential activities of the three plastid RNA polymerases and showing the integration of plastids into a germination-specific transcriptional programme. All three RNA polymerases are active during imbibition; that is, at 4 °C in darkness. However, activity of plastid-encoded RNA polymerase (PEP) is restricted to the rrn operon. After cold release, PEP changes specificity by also transcribing photosynthesis-related genes. The period of germination and radicle outgrowth is further characterized by remarkable antisense RNA production that diminishes during greening when photosynthesis-related mRNAs accumulate to their highest but to very different steady-state levels. During stratification and germination mRNA accumulation is not paralleled by protein accumulation, indicating that plastid transcription is more important for efficient germination than translation.

  15. Students' Attitudes toward an After-School Physical Activity Programme

    Science.gov (United States)

    Agbuga, Bulent; Xiang, Ping; McBride, Ron

    2013-01-01

    Though considerable research on student attitudes has been conducted in physical education, little information exists concerning student attitudes toward after-school physical activity programmes. This study assessed students' attitudes toward their after-school physical activity programme located in southwest Texas, USA. Participants included 158…

  16. Stated Uptake of Physical Activity Rewards Programmes Among Active and Insufficiently Active Full-Time Employees.

    Science.gov (United States)

    Ozdemir, Semra; Bilger, Marcel; Finkelstein, Eric A

    2017-04-22

    Employers are increasingly relying on rewards programmes in an effort to promote greater levels of activity among employees; however, if enrolment in these programmes is dominated by active employees, then they are unlikely to be a good use of resources. This study uses a stated-preference survey to better understand who participates in rewards-based physical activity programmes, and to quantify stated uptake by active and insufficiently active employees. The survey was fielded to a national sample of 950 full-time employees in Singapore between 2012 and 2013. Participants were asked to choose between hypothetical rewards programmes that varied along key dimensions and whether or not they would join their preferred programme if given the opportunity. A mixed logit model was used to analyse the data and estimate predicted uptake for specific programmes. We then simulated employer payments based on predictions for the percentage of each type of employee likely to meet the activity goal. Stated uptake ranged from 31 to 67% of employees, depending on programme features. For each programme, approximately two-thirds of those likely to enrol were insufficiently active. Results showed that insufficiently active employees, who represent the majority, are attracted to rewards-based physical activity programmes, and at approximately the same rate as active employees, even when enrolment fees are required. This suggests that a programme with generous rewards and a modest enrolment fee may have strong employee support and be within the range of what employers may be willing to spend.

  17. Issues related to a programme of activities under the CDM

    Energy Technology Data Exchange (ETDEWEB)

    Ellis, J.

    2006-05-15

    need to be defined and clarified (such as what is meant by a programme of activities in the CDM context? How is it different from bundles of CDM projects? Does guidance on bundling also apply to PCDM? Is a programme of activities that is designed to implement a local/national/regional policy or standard eligible under the CDM?); (2) Guidance specific to PCDM may need to be established for some issues. For example, since the EB is examining new approaches to demonstrate additionality prior to COP/MOP2, it may wish to assess whether any future guidance on additionality should distinguish between PCDM and other CDM project activities. Other issues may also warrant guidance (or methodologies) specific to PCDM, such as crediting periods, determining baselines, ex ante definition (or not) of unique project locations.

  18. Costs and benefits of Danish active labour market programmes

    DEFF Research Database (Denmark)

    Jespersen, Svend; Munch, Jakob Roland; Skipper, Lars

    2008-01-01

    Since 1994, unemployed workers in the Danish labour market have participated in active labour market programmes on a large scale. This paper contributes with an assessment of costs and benefits of these programmes. Long-term treatment effects are estimated on a very detailed administrative dataset...

  19. Active Labour Market Programme Participation for Unemployment Insurance Recipients

    DEFF Research Database (Denmark)

    Filges, Trine; Smedslund, Geir; Jørgensen, Anne-Marie Klint

    2016-01-01

    Objective: This review evaluates the effectiveness of Active Labour Market Programme (ALMP) participation on employment status for unemployment insurance recipients. Methods and Analysis: We followed Campbell Collaboration guidelines to conduct a systematic review. Results: A total of 73 studies...

  20. Round one of the Adelaide and Meath Hospital/Trinity College Colorectal Cancer Screening Programme: programme report and analysis based on established international key performance indices.

    LENUS (Irish Health Repository)

    McNamara, D

    2012-02-01

    BACKGROUND: In Ireland, colorectal cancer (CRC) is the second most frequently diagnosed cancer in men, after prostate cancer, and the second most frequently diagnosed cancer in women, after breast cancer. By 2020, the number of new cases diagnosed annually in Ireland is projected to have increased by 79% in men and 56% in women. Organised screening for CRC is already underway or is in the process of being rolled out in several European countries, either at a regional or national level. The Adelaide and Meath Hospital\\/ Trinity College Dublin Colorectal Cancer Screening Programme (TTC-CRC-SP) is Ireland\\'s first pilot population based bowel screening programme. METHOD: Based on a biennial test model the pilot aimed to assess the accuracy of FIT and to evaluate the whole programme based on established international key performance indices. RESULTS: To date 9,993 individuals aged 50-74 years have been invited to participate in the TTC-CRC-SP with over 5,000 FIT\\'s analysed. Overall uptake was 51% and FIT positivity was 10%. The programme has undertaken over 400 screening colonoscopies and detected 154 precancerous adenomas and 38 cancerous lesions. CONCLUSIONS: The first round of The Adelaide and Meath Hospital Tallaght\\/Trinity College Dublin Colorectal Cancer Screening Programme has been highly successful and confirmed that there is an advantage for FIT based two stage bowel cancer screening programmes.

  1. RFID Key Establishment Against Active Adversaries

    CERN Document Server

    Bringer, Julien; Cohen, Gérard; Kindarji, Bruno

    2010-01-01

    We present a method to strengthen a very low cost solution for key agreement with a RFID device. Starting from a work which exploits the inherent noise on the communication link to establish a key by public discussion, we show how to protect this agreement against active adversaries. For that purpose, we unravel integrity $(I)$-codes suggested by Cagalj et al. No preliminary key distribution is required.

  2. Introducing an enhanced recovery programme to an established totally intracorporeal robot-assisted radical cystectomy service.

    Science.gov (United States)

    Collins, Justin W; Adding, Christofer; Hosseini, Abolfazl; Nyberg, Tommy; Pini, Giovannalberto; Dey, Linda; Wiklund, Peter N

    2016-01-01

    The aim of this study was to assess the effect of introducing an enhanced recovery programme (ERP) to an established robot-assisted radical cystectomy (RARC) service. Data were prospectively collected on 221 consecutive patients undergoing totally intracorporeal RARC between December 2003 and May 2014. The ERP was specifically designed to support an evolving RARC service, where increasing proportions of patients requiring radical cystectomy underwent RARC. Patient demographics and outcomes before and after implementation of the ERP were compared. The primary endpoint was length of stay (LOS). Secondary outcomes included age, American Society of Anesthesiologists (ASA) score, preoperative staging, operative time, complications and readmissions. Differences in outcomes between patients before and after implementation of ERP were tested with the Jonckheere-Terpstra trend test and quantile regression with backward selection. Following implementation of the ERP, the demographics of the patients (n = 135) changed, with median age increasing from 66 to 70 years (p service evolved from selected patients to a general service. Despite worsening demographics, LOS decreased following ERP implementation. This evidence-based ERP safely standardized perioperative care, resulting in decreased LOS and decreased variability in LOS.

  3. PROGRAMME

    African Journals Online (AJOL)

    MEASUREMENT OF SURVIVAL IN A PRIVATE. SECTOR HIV/AIDS DISEASE ... during the first 4 years of the programme was published in 2003.' The purpose of this ... that their scheme offers a Dl\\/IP, and must be willing to disclose their HlV ...

  4. Digitally Controlled ’ProgrammableActive Filters.

    Science.gov (United States)

    1985-12-01

    Mitra, S. K., Analysis and Synthesis of Linear Active .. Networks, Wiley, New York, 1969. * 6. Sedra , A. S. and Smith , K. C., "A Second-Generation...Current Conveyor and its Applications," IEEE Trans. Circuit Theory, Vol. CT-17, pp. 132-134, 1970. 7. Sedra , A. S., "A New Approach to Active Network...CT-18, pp. 358-361, May 1971. 27. Hamilton, T. A., and Sedra , A. S., "Some New IJ Configurations for Active Filters," IEEE Trans. Circuit Tehory, Vol

  5. Primer on CDM programme of activities

    Energy Technology Data Exchange (ETDEWEB)

    Hinostroza, M. (UNEP Risoe Centre, Roskilde (Denmark)); Lescano, A.D. (A2G Carbon Partners (Peru)); Alvarez, J.M. (Ministerio del Ambiente del Peru (Peru)); Avendano, F.M. (EEA Fund Management Ltd. (United Kingdom)

    2009-07-01

    As an advanced modality introduced in 2005, the Programmatic CDM (POA) is expected to address asymmetries of participation, especially of very small-scale project activities in certain areas, key sectors and many countries with considerable potential for greenhouse gas emission reductions, not reached by the traditional single-project-based CDM. Latest experiences with POAs and the recently finalized official guidance governing the Programmatic CDM are the grassroots of this Primer, which has the purpose of supporting the fully understanding of rules and procedures of POAs by interpreting them and analyzing real POA cases. Professional and experts from the public and private entities have contributed to the development of this Primer, produced by the UNEP Risoe Centre, as part of knowledge support activities for the Capacity Development for the CDM (CD4CDM) project. The overall objective of the CD4CDM is to develop the capacities of host countries to identify, design, approve, finance, implement CDM projects and commercialize CERs in participating countries. The CDM4CDM is funded by the Netherlands Ministry of Foreign Affairs. (author)

  6. Yugoslavia. "Migration" -- programme activities targeting men.

    Science.gov (United States)

    Dzeletovic, A; Matovic-miljanovic, S

    1999-01-01

    In Yugoslavia, companies send their workers to different parts of the world, including countries with a high incidence of AIDS. It has been noted that it is characteristic for migrants to accommodate themselves to foreign conditions, which subsequently lead to health problems, especially with regards to reproductive and sexual health. Often, in the case of partner separation, men may seek sexual relations with an unknown partner and/or neglect to use proper protection. According to research carried out in Yugoslavia, there are critical gaps in workers' knowledge on sexual and reproductive health. Based on research results, an educational program for migrants, designed to train and strengthen individuals¿ capabilities and modify their risky behavior, was created. Program activities include production of brochures targeting those people travelling to countries with a high incidence of HIV/AIDS. In addition, a process for creating more cooperation between the state and other organizations at regional and local levels was initiated.

  7. Certain aspects of the psychological analysis of programmer activity. [selection of computer programmers

    Science.gov (United States)

    Bondarovskaya, V. M.

    1975-01-01

    The psychological analysis of programmer activity showed that one of its basic characteristics is the need to employ formal languages. In determining ways of effectively mastering the capacity to write algorithms in the algorithmic language, it is expedient to proceed from its similarity to the living languages and the language of mathematical formulas, and to choose certain psychological principles of mastering foreign languages and mathematical symbols in teaching the algorithmic language. General models of the input language significantly increase the effectiveness of its mastery and permit the development of thinking on the part of the students.

  8. Establishing an Online HIV Peer Helping Programme: A Review of Process Challenges and Lessons Learned

    Science.gov (United States)

    Harris, Gregory E.; Corcoran, Valerie; Myles, Adam; Lundrigan, Philip; White, Robert; Greidanus, Elaine; Savage, Stephanie L.; Pope, Leslie; McDonald, James; Yetman, Gerard

    2015-01-01

    Background: Online peer support can be a valuable approach to helping people living with HIV, especially in regions with large rural populations and relatively centralised HIV services. Design: This paper focuses on a community-university partnership aimed at developing an online peer support programme in the Canadian province of Newfoundland and…

  9. Establishing an Online HIV Peer Helping Programme: A Review of Process Challenges and Lessons Learned

    Science.gov (United States)

    Harris, Gregory E.; Corcoran, Valerie; Myles, Adam; Lundrigan, Philip; White, Robert; Greidanus, Elaine; Savage, Stephanie L.; Pope, Leslie; McDonald, James; Yetman, Gerard

    2015-01-01

    Background: Online peer support can be a valuable approach to helping people living with HIV, especially in regions with large rural populations and relatively centralised HIV services. Design: This paper focuses on a community-university partnership aimed at developing an online peer support programme in the Canadian province of Newfoundland and…

  10. Establishing an educational programme for nurses to supply emergency hormonal contraception (combined method) to protocol.

    Science.gov (United States)

    Brittain, D

    1999-10-01

    This paper gives an account of an innovative educational programme developed by the Department of Midwifery Studies at the University of Central Lancashire (UCLAN) in 1995. The North West Regional Health Authority (NWRHA) approached the Department of Midwifery Studies to develop an educational programme for family planning nurses to supply the combined method of emergency hormonal contraception (EHC) under protocol when a doctor was not present. The purpose was to increase the availability and accessibility of EHC for young people in the North West region. The 3-day programme was designed to complement previous ENB 901/900 training, and also to provide the nurses with the specific skills and knowledge required to undertake this new role. One hundred and thirty-nine nurses from the North West area attended the programme between 1995-1998. Students were assessed both theoretically and clinically. Extending the role of family planning nurses to supply EHC gives purchasers and providers of sexual health care the potential to offer a wider range of accessible services. The recently published interim Crown Report1 on the supply and administration of medicines under group protocols states that protocols should specify clear arrangements for professional responsibility and accountability. Appropriate training is essential to ensure that the extended role of the nurse in family planning is fully understood.

  11. Establishing a generic training programme for future junior doctors: a role for neurosurgery within the framework of clinical neurosciences.

    OpenAIRE

    Nadarajah, Ramesh; Amin, Amit; Aldlyami, Ehabb; Kang, Niel; Wong, James Min-Leong; Selway, Richard; Gullan, Richard

    2005-01-01

    INTRODUCTION: To describe the opinion of junior doctors in neurosurgery in the UK and Eire about future reforms to training, and to relate this to the establishment of a generic neurosciences training programme. METHODS: A postal questionnaire survey of neurosurgery units in UK and Eire (36 units). All senior house officers (SHOs) taking part in a neurosurgery on-call rota during the 6 months between February and August 2003 (n=236); 190 respondents (response rate 81% overall, 90% neurosurger...

  12. Sport Activity and Eating Habits of People Who Were Attending Special Obesity Treatment Programme

    OpenAIRE

    Videmšek, Mateja; Štihec, Jože; Karpljuk, Damir; Starman, Anja

    2008-01-01

    The aims of the study were to analyse the sport activity and eating habits of obese people in their childhood and adulthood. The research was underpinned by a survey questionnaire containing 37 variables which was completed by 71 people attending the obesity programme. The frequencies and contingency tables were calculated, whereas statistical significance was established at a 5% significance level. The analysis of the results showed that more than one-half of the survey responden...

  13. How to Establish a Bioinformatics Postgraduate Degree Programme: A Case Study from South Africa

    CERN Document Server

    Machanick, Philip

    2014-01-01

    The Research Unit in Bioinformatics at Rhodes University (RUBi), South Africa offers a Masters of Science in Bioinformatics. Growing demand for Bioinformatics qualifications results in applications from across Africa. Courses aim to bridge gaps in the diverse backgrounds of students who range from biologists with no prior computing exposure to computer scientists with no biology background. The programme is evenly split between coursework and research, with diverse modules from a range of departments covering mathematics, statistics, computer science and biology, with emphasis on application to bioinformatics research. The early focus on research helps bring students up to speed with working as a researcher. We measure success of the programme by the high rate of subsequent entry to PhD study: 10 out of 14 students who completed in the years 2011-2013.

  14. Towards the establishment and standardization of a veterinary antimicrobial resistance surveillance and monitoring programme in South Africa

    Directory of Open Access Journals (Sweden)

    H. Nel

    2004-11-01

    Full Text Available The objective of this study was to establish a repeatable, standardized laboratory procedure for monitoring the development of antimicrobial resistance in bacteria isolated from animals and food of animal origin in South Africa, with reagents prepared in-house. The emergence of resistance and the spread of resistant bacteria can be limited by implementing a veterinary antimicrobial drug policy, in which inter alia systematic monitoring and prudent use play essential roles. The bacteria included in this study represented three different categories, namely zoonotic bacteria (Salmonella, indicator bacteria (Escherichia coli, Enterococcus faecalis and Enterococcus faecium and veterinary pathogens (Mannheimia haemolytica. Thirty isolates of each species were collected with the aim of standardizing the laboratory methodology for a future national veterinary surveillance and monitoring programme. Susceptibility to ten selected antimicrobial drugs was determined by means of minimum inhibitory concentrations (MICs using the microdilution method. The method according to the National Committee for Clinical Laboratory Standards was used as the standard. Multi-well plates containing varying dilutions of antimicrobial drugs and prepared in-house for MIC determinations, yielded repeatable results. Storage of plates for 2 months at -70 oC did not influence results meaningfully. Within this limited sample of bacteria, MIC results did not indicate meaningful resistance against any of the ten selected antimicrobial drugs. The findings of the study will be used to establish a national veterinary antimicrobial resistance surveillance and monitoring programme in South Africa. To allow for international comparison of data, harmonisation of the surveillance and monitoring programme in accordance with global trends is encouraged. Ideally it should be combined with a programme monitoring the quantities of antimicrobial drugs used. The aim is to contribute to slowing down

  15. Sport activity and eating habits of people who were attending special obesity treatment programme.

    Science.gov (United States)

    Videmsek, Mateja; Stihec, Joze; Karpljuk, Damir; Starman, Anja

    2008-09-01

    The aims of the study were to analyse the sport activity and eating habits of obese people in their childhood and adulthood. The research was underpinned by a survey questionnaire containing 37 variables which was completed by 71 people attending the obesity programme. The frequencies and contingency tables were calculated, whereas statistical significance was established at a 5% significance level. The analysis of the results showed that more than one-half of the survey respondents joined the obesity programme primarily for reasons of health and well-being. Most obese people did not engage in any organised sport activity in their childhood, nor did most of their parents. The respondents practiced sport in their childhood to a greater extent if their parents were also physically active and if they guided and encouraged their children. No less than one-third of the respondents were overweight in their childhood, of whom two-thirds did not participate in any organised sport activity. The majority of the respondents (85.9%) are currently engaged in an organised sport activity in their adulthood, mainly due to their participation in the weight reduction programme; most of them practice sport twice a week. Their eating habits are encouraging; the share of skipped meals is considerably lower and practically negligible compared to that in childhood. It has to be emphasized that most of them are of opinion that obese people have difficulties finding expert information on obesity, nutrition and sport activities as well as weight management centers and institutions.

  16. How Belgium helped establish a surveillance programme for Argentina's Atucha-2

    Energy Technology Data Exchange (ETDEWEB)

    Mitev, Lubomir [NucNet, Brussels (Belgium)

    2015-02-15

    Collaboration between Belgian experts and Argentina on the commissioning of Argentine reactors helped overcome problems caused by delays with construction. Marc Scibetta, deputy manager for nuclear materials science, from the Belgian Nuclear Research Centre (SCK CEN) gave an interview in which he told some facts to Lubomir Mitev of NucNet. The cooperation between SCK CEN an Argentina's Comision Nacional de Energia Atomica (CNEA) started in 2002. The first project was a support for the safety evaluation of the Atucha-1 reactor pressure vessel. When Argentina resumed the construction of Atucha-2 in 2006 - originally, construction started in 1981 but was suspended in 1985 due to financial reasons -, SCK CEN was asked to develop and implement a surveillance programme for the unit.

  17. Active Labour Market Programme Participation for Unemployment Insurance Recipients

    DEFF Research Database (Denmark)

    Filges, Trine; Smedslund, Geir; Jørgensen, Anne-Marie Klint

    2016-01-01

    Objective: This review evaluates the effectiveness of Active Labour Market Programme (ALMP) participation on employment status for unemployment insurance recipients. Methods and Analysis: We followed Campbell Collaboration guidelines to conduct a systematic review. Results: A total of 73 studies...... met the inclusion criteria and were critically appraised by the review authors. The available evidence suggests that there is a general effect of participating in ALMP. The findings are mixed, however, depending on the approach used to investigate the effect, with no effect found of being assigned...

  18. Active ingredients in anti-stigma programmes in mental health.

    Science.gov (United States)

    Pinfold, Vanessa; Thornicroft, Graham; Huxley, Peter; Farmer, Paul

    2005-04-01

    This paper draws upon a review of the relevant literature and the results of the recent Mental Health Awareness in Action (MHAA) programme in England to discuss the current evidence base on the active ingredients in effective anti-stigma interventions in mental health. The MHAA Programme delivered educational interventions to 109 police officers, 78 adults from different community groups whose working lives involved supporting people with mental health problems but who had received no mental health training and 472 schools students aged 14-15. Each adult target group received two intervention sessions lasting two hours. The two school lessons were 50 minutes each. Knowledge, attitudes and behavioural intent were assessed at baseline and follow-up. In addition focus groups were held with mental health service users to explore the impact of stigma on their lives and facilitators of educational workshops were interviewed to provide expert opinion on 'what works' to reduce psychiatric stigma. Personal contact was predictive of positive changes in knowledge and attitudes for the school students but not the police officers or community adult group. The key active ingredient identified by all intervention groups and workshop facilitators were the testimonies of service users. The statements of service users (consumers) about their experience of mental health problems and of their contact with a range of services had the greatest and most lasting impact on the target audiences in terms of reducing mental health stigma.

  19. An inexpensive programmable illumination microscope with active feedback

    Science.gov (United States)

    Tompkins, Nathan; Fraden, Seth

    2016-02-01

    We have developed a programmable illumination system capable of tracking and illuminating numerous objects simultaneously using only low-cost and reused optical components. The active feedback control software allows for a closed-loop system that tracks and perturbs objects of interest automatically. Our system uses a static stage where the objects of interest are tracked computationally as they move across the field of view allowing for a large number of simultaneous experiments. An algorithmically determined illumination pattern can be applied anywhere in the field of view with simultaneous imaging and perturbation using different colors of light to enable spatially and temporally structured illumination. Our system consists of a consumer projector, camera, 35-mm camera lens, and a small number of other optical and scaffolding components. The entire apparatus can be assembled for under 4,000. Supplemental matlab code is available to assist in the setup of the active feedback software.

  20. An inexpensive programmable illumination microscope with active feedback

    Science.gov (United States)

    Tompkins, Nathan; Fraden, Seth

    2016-01-01

    We have developed a programmable illumination system capable of tracking and illuminating numerous objects simultaneously using only low-cost and reused optical components. The active feedback control software allows for a closed-loop system that tracks and perturbs objects of interest automatically. Our system uses a static stage where the objects of interest are tracked computationally as they move across the field of view allowing for a large number of simultaneous experiments. An algorithmically determined illumination pattern can be applied anywhere in the field of view with simultaneous imaging and perturbation using different colors of light to enable spatially and temporally structured illumination. Our system consists of a consumer projector, camera, 35-mm camera lens, and a small number of other optical and scaffolding components. The entire apparatus can be assembled for under $4,000. PMID:27642182

  1. Programme Costing of a Physical Activity Programme in Primary Prevention: Should the Costs of Health Asset Assessment and Participatory Programme Development Count?

    Directory of Open Access Journals (Sweden)

    Silke B. Wolfenstetter

    2012-01-01

    Full Text Available This analysis aims to discuss the implications of the “health asset concept”, introduced by the WHO, and the “investment for health model” requiring a “participatory approach” of cooperative programme development applied on a physical activity programme for socially disadvantaged women and to demonstrate the related costing issues as well as the relevant decision context. The costs of programme implementation amounted to €48,700. Adding the costs for developing the programme design of €48,800 results in total costs of €97,500; adding on top of that the costs of asset assessment running to €35,600 would total €133,100. These four different cost figures match four different types of potentially relevant decisions contexts. Depending on the decision context the total costs, and hence the incremental cost-effectiveness ratio of a health promotion intervention, could differ considerably. Therefore, a detailed cost assessment and the identification of the decision context are of crucial importance.

  2. Electricity research programme - Overview report on activities in 2005; Programm Elektrizitaet. Ueberblicksbericht zum Forschungsprogramm 2005

    Energy Technology Data Exchange (ETDEWEB)

    Brueniger, R.

    2006-07-01

    This overview-report for the Swiss Federal Office of Energy (SFOE) summarises the work done in 2005 in the various research areas covered by the Swiss Electricity Research programme. Work done in the programme's two main areas - technologies and efficient applications - is reviewed. In the technologies area, high-temperature superconductivity - and especially its use in power-generation facilities - is looked at, as are the topics of energy conversion and thermo-electric power generation. Further, energy storage using compressed-air is discussed. Power distribution and the use of controllable storage in the low-voltage mains is briefly commented on, as is distributed power generation. Information and communications technologies are reviewed, as is work done in the electrical drives area. Work in other areas summarised includes lighting and uninterruptible power-supplies. Co-operation with Swiss institutions and international organisations such as the IEA is reviewed. Implementation work in the pilot and demonstration area is commented on. This includes work in various areas ranging from set-top boxes through to the optimisation of compressed-air systems and electrical drives as well as codes of conduct and agreements for water-dispensers and cooling systems in retail applications and the optimisation of wastewater treatment plant. The report is completed with a list of current research and development projects.

  3. [Worksite physical activity and nutrition programmes: beneficial to our health and wallet?].

    Science.gov (United States)

    van Wier, Marieke F; van Dongen, J M Hanneke; van Tulder, Maurits W

    2013-01-01

    The unhealthy lifestyle of many Dutch employees may negatively influence their health in general as well as their ability to work. Worksite physical activity, nutrition or combination programmes could improve employee health and, as a consequence of this, reduce costs due to illness absenteeism, early retirement, and health care use. In this article, we present current scientific research in terms of health-related effectiveness, cost-effectiveness and the financial return of these programmes. There is moderate evidence that programmes aimed at nutrition, as well as combined nutrition-and-physical activity programmes, do result in modest improvements in weight-related outcomes and the consumption of fruit, vegetables and fat after 6-12 months. There is also moderate evidence that physical fitness programmes improve physical activity and fitness in the short term. The programmes result in financial returns for the employer, but this conclusion is based on non-randomised studies. No firm conclusions can be drawn regarding their cost-effectiveness. Wide implementation of singular worksite physical activity, nutrition or combination programmes is therefore currently discouraged. It would probably be more effective and economical to set up a broad range of interventions and measures. This requires more research, however, as well as more opportunities for offering tailor-made programmes.

  4. Establishing the credibility for the Midbrain Activation Workshop

    OpenAIRE

    Fu, Hao

    2015-01-01

    The purpose of this thesis was to establish the creditability of the Midbrain Activation workshop to the Chinese public. The workshop is basically a brain development training course for the kids. Based on that choosing the social media includes the online advertising, video marketing can enhance the consumer’s perception to the Midbrain Activation Workshop which will results in improving business profitability. By implementing a variety of social media channels as their marketing strategi...

  5. The Effect of Sanctions and Active Labour Market Programmes on the Exit Rate From Unemployment

    DEFF Research Database (Denmark)

    Ahmad, Nisar; Svarer, Michael

    ). Hence, modeling only one of them as treatment might over or underestimate the true effect. Therefore, by using a multivariate mixed proportional hazard model (MMPH), we model the hazard rate out of unemployment along with the sanction rate and hazard rate into active labour market programmes. We......This paper simultaneously investigates the effectiveness of benefit sanctions and active labour market programmes on the exit rate from unemployment using Danish data. In the data about one third of the individuals who are sanctioned also participate in some active labour market programmes (ALMPs...... optimally select the number of supports point for the distribution of unobserved heterogeneity. Results show that pre-specifying two support points underestimates the effect of sanctions and active labour market programmes. Failing to control for selectivity for sanctions not only underestimates...

  6. The Effect of Sanctions and Active Labour Market Programmes on the Exit Rate From Unemployment

    DEFF Research Database (Denmark)

    Ahmad, Nisar; Svarer, Michael

    2009-01-01

    ). Hence, modeling only one of them as treatment might over or underestimate the true effect. Therefore, by using a multivariate mixed proportional hazard model (MMPH), we model the hazard rate out of unemployment along with the sanction rate and hazard rate into active labour market programmes. We......This paper simultaneously investigates the effectiveness of benefit sanctions and active labour market programmes on the exit rate from unemployment using Danish data. In the data about one third of the individuals who are sanctioned also participate in some active labour market programmes (ALMPs...... optimally select the number of supports point for the distribution of unobserved heterogeneity. Results show that pre-specifying two support points underestimates the effect of sanctions and active labour market programmes. Failing to control for selectivity for sanctions not only underestimates...

  7. The Effect of Sanctions and Active Labour Market Programmes on the Exit Rate From Unemployment

    DEFF Research Database (Denmark)

    Ahmad, Nisar; Svarer, Michael

    2009-01-01

    ). Hence, modeling only one of them as treatment might over or underestimate the true effect. Therefore, by using a multivariate mixed proportional hazard model (MMPH), we model the hazard rate out of unemployment along with the sanction rate and hazard rate into active labour market programmes. We......This paper simultaneously investigates the effectiveness of benefit sanctions and active labour market programmes on the exit rate from unemployment using Danish data. In the data about one third of the individuals who are sanctioned also participate in some active labour market programmes (ALMPs...... optimally select the number of supports point for the distribution of unobserved heterogeneity. Results show that pre-specifying two support points underestimates the effect of sanctions and active labour market programmes. Failing to control for selectivity for sanctions not only underestimates...

  8. Piloting a physical activity centred education programme for adults with a brain injury.

    Science.gov (United States)

    Driver, Simon; Irwin, Kelley; Woolsey, Anne; Warren, Ann Marie

    2013-01-01

    To pilot test a physical activity centred education (PACE) programme for adults with a brain injury. Purposive sampling was utilized from a convenience sample of nine adults with a brain injury (five female; four male). The sample completed an 8-week health promotion programme focused on improving physical activity behaviours. Participants completed measures of self-efficacy, stage of change and rehabilitation outcomes pre- and post-programme. Descriptive analysis, effect sizes (ES) and percentage change in variables were assessed. Results indicated improved rehabilitation outcomes as participants decreased from moderate to mild limitation (ES = 1.67). Furthermore, participants reported increased self-efficacy (ES = 0.41) and intention to be active. Specialists are challenged to find modes of rehabilitation that improve the health of individuals with a brain injury. Pilot results from the PACE programme indicate that education about physical activity may play an important role in the rehabilitation process and lead to improved health outcomes.

  9. Combustion chemistry - activities in the CHEK research programme

    Energy Technology Data Exchange (ETDEWEB)

    Dam-Johansen, K.; Johnsson, J.E.; Glarborg, P.; Frandsen, F.; Jensen, A.; Oestberg, M. [Technical Univ. of Denmark, Lyngby (Denmark). Dept. of Chemical Engineering

    1997-10-01

    The combustion chemistry in the oxidation of fossil fuels and biofuels determines together with mixing and heat transfer the required size of a furnace, the emission of gaseous pollutants, and the formation of ash and deposits on surfaces. This presentation describes technologies for solid fuels combustion and gives a summary of the fuels, the pollutant chemistry and the inorganic chemistry in combustion processes. Emphasis is put on the work carried out in the CHEC (Combustion and Harmful Emission Control) Research Programme. (orig.)

  10. Active Labour Market Programme Participation for Unemployment Insurance Recipients: A Systematic Review

    DEFF Research Database (Denmark)

    Filges, Trine; Smedslund, Geir; Knudsen, Anne-Sofie Due

    2015-01-01

    BACKGROUND During the 1990s, many countries introduced Active Labour Market Programmes (ALMPs) in an effort to reduce unemployment. The introduction of ALMPs is often motivated by the need to upgrade the skills of especially those suffering long-term unemployment to improve their productivity and...... assistance and education) are part-time and have a short duration (e.g. few days/weeks). It is possible to classify these programmes into a set of four core categories: A: (labour market) training, B: Private sector programmes, C: direct employment programmes in the public sector and D: Job search assistance....... The categories we use broadly correspond to classifications that have been suggested and used by the OECD and Eurostat (OECD, 2004 and Eurostat, 2005), even though there are differences between OECD and Eurostat in how they define and categorise these programmes. OBJECTIVES The objective of this systematic...

  11. Utilisation of Wearable Computing for Space Programmes Test Activities Optimasation

    Science.gov (United States)

    Basso, V.; Lazzari, D.; Alemanni, M.

    2004-08-01

    New technologies are assuming a relevant importance in the Space business domain also in the Assembly Integration and Test (AIT) activities allowing process optimization and capability that were unthinkable only few years ago. This paper has the aim to describe Alenia Spazio (ALS) gained experience on the remote interaction techniques as a results of collaborations established both on European Communities (EC) initiatives, with Alenia Aeronautica (ALA) and Politecnico of Torino (POLITO). The H/W and S/W components performances increase and costs reduction due to the home computing massive utilization (especially demanded by the games business) together with the network technology possibility (offered by the web as well as the hi-speed links and the wireless communications) allow today to re-think the traditional AIT process activities in the light of the multimedia data exchange: graphical, voice video and by sure more in the future. Aerospace business confirm its innovation vocation which in the year '80 represents the cradle of the CAD systems and today is oriented to the 3D data visualization/ interaction technologies and remote visualisation/ interaction in collaborative way on a much more user friendly bases (i.e. not for specialists). Fig. 1 collects AIT extended scenario studied and adopted by ALS in these years. ALS experimented two possibilities of remote visualization/interaction: Portable [e.g. Fig.2 Personal Digital Assistant (PDA), Wearable] and walls (e.g.VR-Lab) screens as both 2D/3D visualisation and interaction devices which could support many types of traditional (mainly based on EGSE and PDM/CAD utilisation/reports) company internal AIT applications: 1. design review support 2. facility management 3. storage management 4. personnel training 5. integration sequences definition 6. assembly and test operations follow up 7. documentation review and external access to AIT activities for remote operations (e.g. tele-testing) EGSE Portable Clean room

  12. From activity to learning: using cultural historical activity theory to model school library programmes and practices

    Directory of Open Access Journals (Sweden)

    E.M. Meyers

    2007-01-01

    Full Text Available Introduction. changes in educational policy and practice demand that we examine school library programmes from a new perspective. As a model that takes a developmental view of minds in context, Cultural Historical Activity Theory is particularly well suited to the study of school libraries and the learning that occurs therein. This paper focuses on the activity theoretic concepts of 'contradictions' and 'expansive learning' as they relate to the development of best practices. Method. Developmental Work Research was applied as a guiding methodology in an intervention study of six high school libraries in Washington State, USA. Library activity is illustrated from multiple perspectives using a triangulated, qualitative approach. Analysis. contradictions and tensions in the general school library activity system are identified, and an intervention was designed to facilitiate the development of expansive instruments. A case example illustrates a second level of analysis and specific points of intervention. Results. analysis reveals that the tensions and contradictions provide opportunities for expansive learning on the part of the teacher-Librarians. The research team can use practitioners' zones of proximal development to guide the alignment of library programme goals and practices. Conclusion. : some limitations and future promise of the framework and its application are discussed. The proposed activity theory toolkit suggest a new way of exploring the practices of teacher-librarians, incorporating research evidence, professional expertise, and reflective decision making.

  13. Combustion chemistry. Activities in the CHEC research programme

    Energy Technology Data Exchange (ETDEWEB)

    Dam-Johansen, K.; Johnsson, J.E.; Glarborg, P.; Frandsen, F.; Jensen, A.; Oestberg, M. [Technical Univ. of Denmark, Dept. of Chemical Engineering, Lyngby (Denmark)

    1996-12-01

    The combustion chemistry in the oxidation of fossil fuels and biofuels determines together with mixing and heat transfer the required size of a furnace, the emission of gaseous pollutants, and the formation of ash and deposits on surfaces. This paper describes technologies for solid fuels combustion and gives a summary of the fuels, the pollutant chemistry and the inorganic chemistry in combustion processes. Emphasis is put on the work carried out in the CHEC (Combustion and Harmful Emission Control Research Programme). (au) 173 refs.

  14. Adult Workers in Theory or Practice? : Lone Mothers’ Participation in Active Labour Market Programmes in Germany

    Directory of Open Access Journals (Sweden)

    Cordula Zabel

    2015-03-01

    Full Text Available This paper examines lone mothers’ participation in active labour market programmes in Germany. Since the 2005 Hartz IV employment and welfare policy reforms, expectations that non-em- ployed parents receiving means-tested benefits should be ready for employment or labour market programme participation have grown stronger. However, discretion for programme assignments is left to individual caseworkers. As a consequence, it is not clear to what extent the formal policy orientation towards an adult worker model of the family is reflected in practical policy implemen- tations. Thus, lone mothers’ participation in active labour market programmes is studied empiri- cally here on the basis of large-scale administrative data, using event-history analysis. Findings are that lone mothers are treated as adult workers with respect to workfare and training pro- grammes even when their children are still quite young. As soon as their youngest child is 3 - 5 years old, lone mothers’ transition rates into these programmes are as high as for childless single women. In the case of programmes that provide more direct pathways into regular employment, like job subsidies and in-firm training programmes, however, participation rates for lone mothers of young children are substantially lower than for childless single women.

  15. Oxytocin discontinuation after the active phase of labor is established.

    Science.gov (United States)

    Vlachos, Dimitrios-Efthymios G; Pergialiotis, Vasilios; Papantoniou, Nikolaos; Trompoukis, Stamoulis; Vlachos, Georgios D

    2015-08-01

    Despite the widespread usage of oxytocin, there is still no consensus on its mode of administration. The scope of the present meta-analysis was to assess the effect of oxytocin discontinuation after the active phase of labor is established on maternal fetal and neonatal outcomes. We searched Medline, Scopus, Popline, ClinicalTrials.gov and Google Scholar databases. Eight studies were finally retrieved, which involved 1232 parturient. We observed significantly decreased rates of cesarean sections among parturient that discontinued oxytocin (OR 0.51, 95% CI 0.35, 0.74) as well as decreased rates of uterine hyperstimulation (OR 0.33, 95% CI 0.19, 0.58). Similarly, cases of non-reassuring fetal heart rates were fewer among women that did not receive oxytocin after the establishment of the active phase of labor (OR 0.63, 95% CI 0.41, 0.97). Keeping in mind the aforementioned maternal and neonatal adverse effects that seem to result from infusion of oxytocin until delivery, future practice should aim towards its discontinuation after the establishment of the active phase of labor, as it does not seem to influence the total duration of labor. Future studies should aim towards specific populations of parturient in order to clarify whether different approaches are needed.

  16. Establishing New Cut-Off Limits for Galactose 1-Phosphate-Uridyltransferase Deficiency for the Dutch Newborn Screening Programme.

    Science.gov (United States)

    Kemper, E A; Boelen, A; Bosch, A M; van Veen-Sijne, M; van Rijswijk, C N; Bouva, M J; Fingerhut, R; Schielen, P C J I

    2016-05-21

    Newborn screening for classical galactosemia in the Netherlands is performed by five laboratories and is based on the measurement of galactose 1-phosphate-uridyltransferase (GALT) activity and total galactose (TGAL) in heel prick blood spots. Unexpected problems with the GALT assay posed a challenge to switch to a new assay. The aim of this study was to make an analytical and clinical evaluation of GALT assays to replace the current assay and to establish new cut-off values (COVs).First, the manual assay from PerkinElmer (NG-1100) and the GSP assay were compared by analyzing 626 anonymous heel prick samples in parallel. Secondly, a manual GSP method was evaluated and 2,052 samples were compared with the automated GSP assay. Finally, a clinical evaluation was performed by collecting data from 93 referred newborns.No satisfactory correlation was observed between GALT activity measured with the manual NG-1100 assay and the automated GSP assay. An acceptable correlation was found between the manual and automated GSP assay. Intra- and inter-assay variation of the automated GSP were 1.8-10.0% and 3.1-13.9%, respectively. Evaluation of clinical data demonstrated that adjusting the COVs for GALT to 2.0 U/dl and TGAL to 1,100 μmol/l improved specificity of screening for classical galactosemia.An assay designed for automated processing to measure GALT activity in heel prick samples works equally well when processed manually. We therefore adopted both methods in the Dutch screening laboratories. As a result of this evaluation new COVs for GALT and TGAL have been introduced and are valid from July 2015.

  17. Objects prompt authentic scientific activities among learners in a museum programme

    Science.gov (United States)

    Achiam, Marianne; Simony, Leonora; Kramer Lindow, Bent Erik

    2016-04-01

    Although the scientific disciplines conduct practical work in different ways, all consider practical work as the essential way of connecting objects and phenomena with ideas and the abstract. Accordingly, practical work is regarded as central to science education as well. We investigate a practical, object-based palaeontology programme at a natural history museum to identify how palaeontological objects prompt scientific activity among upper secondary school students. We first construct a theoretical framework based on an analysis of the programme's palaeontological content. From this, we build our reference model, which considers the specimens used in the programme, possible palaeontological interpretations of these specimens, and the conditions inherent in the programme. We use the reference model to analyse the activities of programme participants, and illustrate how these activities are palaeontologically authentic. Finally, we discuss our findings, examining the mechanism by which the specimens prompt scientific activities. We also discuss our discipline-based approach, and how it allows us to positively identify participants' activities as authentic. We conclude by discussing the implications of our findings.

  18. [Physical activity programmes to reduce overweight and obesity in children and adolescents; a systematic review].

    Science.gov (United States)

    Aguilar Cordero, M J; Ortegón Piñero, A; Mur Vilar, N; Sánchez García, J C; García Verazaluce, J J; García García, I; Sánchez López, A M

    2014-10-01

    Obesity treatment has been the subject of much controversy; various authors have recommended the application of a comprehensive treatment programme, and in the light of this previous research, we consider the question of what is the most effective programme of physical activity to reduce overweight and obesity in children and adolescents. To analyse major studies on the effectiveness of physical activity in reducing overweight and obesity in children and adolescents. Systematic review of the results of physical activity programmes, published in scientific articles, to reduce overweight and obesity. Using an automated database search in PubMed and Google Scholar, conducted from October 2013 to March 2014, we identified 85 valid items. In selecting the items, the criteria applied included the usefulness and relevance of the subject matter and the credibility or experience of the research study authors. The internal and external validity of each of the articles reviewed was taken into account. This review confirmed the effectiveness of physical activity in reducing overweight and obesity in children and adolescents. The most effective programmes were those combining aerobic and anaerobic exercises. It is generally accepted that at least 180 minutes per week should be dedicated to exercise, in the form of three 60-minute sessions of moderate intensity. Such programmes could be sufficient for persons with overweight or obesity. Researchers in this field agree that when a diet based on an appropriate distribution of meals is combined with regular physical activity, they reinforce each other, and thus optimum results are obtained. Weight reduction programmes that take account of family involvement are more effective than nutrition education itself or other routine interventions that fail to consider family involvement. The role of pa rents and of the persons around the child or adolescent is essential to reinforce positive behaviour toward lifestyle change. Copyright AULA

  19. Programmable Current-Mode Universal Active Filters Employing Current Conveyors

    OpenAIRE

    Muhammad Taher Abuelma'atti

    1998-01-01

    Novel current-mode active filter circuits using current-conveyors are presented. The proposed circuits can realize all standard second-order filter functions. The circuits enjoy high output impedances and can, therefore, be easily cascaded to produce higher order filters. Moreover, the realized filter function can be easily programmed using at most a 13-bit digital number without changing the circuit topology.

  20. Effectiveness of a physical activity programme based on the Pilates method in pregnancy and labour.

    Science.gov (United States)

    Rodríguez-Díaz, Luciano; Ruiz-Frutos, Carlos; Vázquez-Lara, Juana María; Ramírez-Rodrigo, Jesús; Villaverde-Gutiérrez, Carmen; Torres-Luque, Gema

    To assess the effectiveness and safety of a physical activity programme based on use of the Pilates method, over eight weeks in pregnant women, on functional parameters, such as weight, blood pressure, strength, flexibility and spinal curvature, and on labour parameters, such as, type of delivery, episiotomy, analgesia and newborn weight. A randomized clinical trial was carried out on pregnant women, applying a programme of physical activity using the Pilates method, designed specifically for this population. A sample consisting of a total of 105 pregnant women was divided into two groups: intervention group (n=50) (32.87±4.46 years old) and control group (n=55) (31.52±4.95 years old). The intervention group followed a physical activity programme based on the Pilates method, for 2 weekly sessions, whereas the control group did not follow the program. Significant improvements (p<0.05) in blood pressure, hand grip strength, hamstring flexibility and spinal curvature, in addition to improvements during labour, decreasing the number of Caesareans and obstructed labour, episiotomies, analgesia and the weight of the newborns were found at the end of the intervention. A physical activity programme of 8 weeks based on the Pilates method improves functional parameters in pregnant women and benefits delivery. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

  1. Evaluation of physical activity programmes for elderly people - a descriptive study using the EFQM' criteria

    Directory of Open Access Journals (Sweden)

    Santos Rute

    2011-02-01

    Full Text Available Abstract Background In the past years, there has been a growing concern in designing physical activity (PA programmes for elderly people, because evidence suggests that such health promotion interventions may reduce the deleterious effects of the ageing process. Quality is an important issue when designing a PA programme for older people. Some studies support the Excellence Model of the European Foundation for Quality Management (EFQM as an operational framework for evaluating the quality of an organization. Within this context, the aim of this study was to characterize the quality management models of the PA programmes developed by Portuguese Local Administration to enhance quality of life for elderly people, according to the criteria of the EFQM Excellence Model. Methods A methodological triangulation was conducted in 26 PA programmes using questionnaire surveys, semi-structured interviews and document analysis. We used standard approaches to the statistical analysis of data including frequencies and percentages for the categorical data. Results Results showed that Processes (65,38%, Leadership (61,03%, Customer results (58,46 and People (51,28% had high percentage occurrences of quality practices. In contrast, Partnerships and resources (45,77%, People results (41,03%, Policy and strategy (37,91%, Key performance results (19,23% and Society results (19,23% had lower percentage occurrences. Conclusions Our findings suggest that although there are some good practices in PA programmes, there are still relevant areas that require improvement.

  2. Evaluation of physical activity programmes for elderly people - a descriptive study using the EFQM' criteria.

    Science.gov (United States)

    Marques, Ana I; Rosa, Maria J; Soares, Pedro; Santos, Rute; Mota, Jorge; Carvalho, Joana

    2011-02-21

    In the past years, there has been a growing concern in designing physical activity (PA) programmes for elderly people, because evidence suggests that such health promotion interventions may reduce the deleterious effects of the ageing process. Quality is an important issue when designing a PA programme for older people. Some studies support the Excellence Model of the European Foundation for Quality Management (EFQM) as an operational framework for evaluating the quality of an organization. Within this context, the aim of this study was to characterize the quality management models of the PA programmes developed by Portuguese Local Administration to enhance quality of life for elderly people, according to the criteria of the EFQM Excellence Model. A methodological triangulation was conducted in 26 PA programmes using questionnaire surveys, semi-structured interviews and document analysis. We used standard approaches to the statistical analysis of data including frequencies and percentages for the categorical data. Results showed that Processes (65,38%), Leadership (61,03%), Customer results (58,46) and People (51,28%) had high percentage occurrences of quality practices. In contrast, Partnerships and resources (45,77%), People results (41,03%), Policy and strategy (37,91%), Key performance results (19,23%) and Society results (19,23%) had lower percentage occurrences. Our findings suggest that although there are some good practices in PA programmes, there are still relevant areas that require improvement.

  3. Evaluation of physical activity programmes for the elderly - exploring the lessons from other sectors and examining the general characteristics of the programmes

    Directory of Open Access Journals (Sweden)

    Clara-Santos Paula

    2011-09-01

    Full Text Available Abstract Background In Portugal, there are several physical activity (PA programmes for elderly people developed by the local government. The importance of these programmes has been increasing since the evidence has shown that this type of health promotion interventions may reduce the deleterious effects of the ageing process. However, no study has already identified the general characteristics of these programmes nor if they use any scheme to assess the quality of the service provided. A widely-used scheme is the EFQM Excellence Model, which will be in the core of our present work. Thus, the main aims of this preliminary study were 1 to identify the general characteristics of the PA programmes developed by the Portuguese Local Public Administration 2 to determine the extent of implementation of quality initiatives in these programmes. Methods Data were collected by an on-line questionnaire sent to all Continental Municipalities (n = 278. Categorical data were expressed as absolute counts and percentages. Continuous data were expressed as the mean and SD. An open-ended question was analysed using qualitative content analysis with QSR NVivo software. Associations between categorical variables were tested by the use of contingency tables and the calculation of chi-square tests. Significance level was set at p ≤ 0.05. Results Results showed: i a total of 125 PA programmes were identified in the 18 districts of the Portugal mainland; ii the main goal of the majority (95.2% was the participants' health promotion; iii different characteristics of the programmes were found according to different regions of the country; iv certain characteristics of the programmes were associated to the existence of other features; v only one PA programme developed quality initiatives. Conclusions In conclusion, although there are many PA programmes for elderly people spread throughout the country, aiming at improving the health of participants, the overwhelming

  4. Oncogenic programmes and Notch activity: an 'organized crime'?

    Science.gov (United States)

    Dominguez, Maria

    2014-04-01

    The inappropriate Notch signalling can influence virtually all aspect of cancer, including tumour-cell growth, survival, apoptosis, angiogenesis, invasion and metastasis, although it does not do this alone. Hence, elucidating the partners of Notch that are active in cancer is now the focus of much intense research activity. The genetic toolkits available, coupled to the small size and short life of the fruit fly Drosophila melanogaster, makes this an inexpensive and effective animal model, suited to large-scale cancer gene discovery studies. The fly eye is not only a non-vital organ but its stereotyped size and disposition also means it is easy to screen for mutations that cause tumours and metastases and provides ample opportunities to test cancer theories and to unravel unanticipated nexus between Notch and other cancer genes, or to discover unforeseen Notch's partners in cancer. These studies suggest that Notch's oncogenic capacity is brought about not simply by increasing signal strength but through partnerships, whereby oncogenes gain more by cooperating than acting individually, as in a ring 'organized crime'.

  5. Hydrogen activities in the European Union work-programme. Paper

    Energy Technology Data Exchange (ETDEWEB)

    Bahbout, A.; Tartaglia, G.P.; Buenger, U.

    2000-07-01

    Looking at some of the national and international developments in hydrogen technology it becomes clear which important contributions the hydrogen technology oriented activities of the EU have helped to prepare and trigger: (a) Transport Energy Strategy (TES): This initiative of 7 major German automobile and mineral oilcompanies is aimed at an industrial consensus on one or two gasoline alternative fuels, which are to be presented to the German Ministry of Transport. An intermediate trend is that hydrogen may become the fuel of choice. (b) BMW: The Bayerischen Motorenwerke have already very early exposed themselves to the vehicle and component development of hydrogen as a vehicle fuel, focussing on a strategy from CNG to LNG and LH{sub 2}. (c) Opel and GM: Opel has recently announced they have chosen hydrogen as the primary long term fuel for their fuel cell vehicles to be commercialized starting in 2004. (d) CFCP: The California Fuel Cell Partnership with partners from industry and politics has announced they are preparing the installation of hydrogen fuel stations aas well as 20-25 fuel cell buses and 30 passenger cars, mainly operated with hydrogen. (e) NEDO: The New Energy and Industrial Technology Development Organization (NEDO) of Japan has announced they are going to build hydrogen pilot refueling stations 18 months ahead of the original schedule to reduce the first-to-market-time. (f) Norway: A study group of Norwegian industry and institutes has carried out a comprehensive study for the Research Ministry on further R and D areas which should be intensified in a national strategy to be prepared for an international hydrogen energy system [SINTEF, 00]. (g) German Greens: The German ecologist party ''Greens'' has announced last week a shift from an anti-car lobbying to fostering greener cars, focussing on renewable hydrogen as a clean fuel. (h) Linde: The largest European Technical Gas Company has announced recently they will strategically

  6. Establishing a reproducible protocol for measuring index active extension strength.

    Science.gov (United States)

    Matter-Parrat, V; Hidalgo Diaz, J J; Collon, S; Salazar Botero, S; Prunières, G; Ichihara, S; Facca, S; Liverneaux, P

    2017-02-01

    The goal of this study was to establish a reproducible protocol to measure active extension strength in the index finger. The secondary objectives consisted in correlating the independent or associated index extension strength to the other fingers force of contraction of the extensor indicis propius with hand dominance. The population studied consisted of 24 healthy volunteers, including 19 women and 20 right-handed individuals. The independent and dependent index extension strength in each hand was measured three times with a dynamometer by three examiners at Day 0 and again at Day 7. Intra and inter-examiner reproducibility were, respectively, >0.90 and >0.75 in all cases. The independent extension strength was lower than the dependent one. There was no difference between the independent index extension strength on the dominant and non-dominant sides. The same was true for the dependent strength. Our results show that our protocol is reproducible in measuring independent and dependent index extension strength. Dominance did not come into account.

  7. Process evaluation of a school based physical activity related injury prevention programme using the RE-AIM framework

    Directory of Open Access Journals (Sweden)

    van Mechelen Willem

    2010-11-01

    Full Text Available Abstract Background In general, only information regarding the effectiveness of an intervention programme is ever published. However, in recent years evaluating the translatability and feasibility of an intervention programme has become more important. Therefore, this paper presents the results of the evaluation of the iPlay programme aimed at preventing physical activity related injuries in primary school children. Methods The iPlay programme targeted injuries gained through physical activity, and consisted of a teacher's manual, informative newsletters and posters, a website, and set exercises to be carried out during physical education (PE classes. In order to evaluate the iPlay programme for translatability and feasibility, teachers, children and parents who participated in the iPlay programme filled out a questionnaire The objective of this study is to describe the results of the process-evaluation of the iPlay programme based on the five dimensions of the RE-AIM framework. Results The results showed that the participation rate of the children was 100% (reach. Nine percent of the schools who were invited to take part were willing to participate in the study (adoption rate. Teachers stated that they implemented the different elements of the programme partly as intended (implementation. The percentage of children and parents who followed the programme was less than expected. In addition, 52% of the teachers indicated that the current iPlay programme could become standard practice in their teaching routine (maintenance. Conclusion The iPlay programme is a first start in the prevention of physical activity related injuries in children, but further improvements need to be made to the programme on the basis of this process evaluation. Trial registration ISRCTN78846684; http://www.controlled-trials.com

  8. New and recently finalised activities within the NKS Programmes for Nordic cooperation on nuclear reactor safety and emergency preparedness

    DEFF Research Database (Denmark)

    Andgren, Karin; Andersson, Kasper Grann; Magnússon, Sigurður M.

    2015-01-01

    Over the years, NKS has provided funding for hundreds of research activities in fields comprising reactor safety, decommissioning, nuclear and radiological emergency preparedness, and management of radioactive waste. Advanced technologies and methods developed under the NKS framework have been used...... within the Nordic countries as well as internationally. Two programme areas are defined under the NKS platform: The NKS-R programme on nuclear reactor safety and the NKS-B programme on emergency preparedness. Three articles, giving an introduction to NKS and its two programmes, were published...

  9. Teacher development programme and worklife practice in interplay: An inquiry into the transition from experienced to established teacher

    DEFF Research Database (Denmark)

    Rump, Camilla Østerberg; Kobayashi, Sofie; Christiansen, Frederik V

    in parallel with TDP participation. They do not tell how this development came about. In this study we use time-line interviews to inquire into how TDP participants match their development as teachers with meaningful engagement in other important work-life practices. We find that they do so by constituting...... of TDP contents and activities and also suggest new avenues for exploring how quality student learning relates to teacher development....

  10. Teacher development programme and worklife practice in interplay: An inquiry into the transition from experienced to established teacher

    DEFF Research Database (Denmark)

    Rump, Camilla Østerberg; Kobayashi, Sofie; Christiansen, Frederik V;

    the notion of ‘the good teacher’ in an array of qualitatively different ways. Importantly, we find that a teacher can be student focused and feel confident about their ability to facilitate quality student learning, but in a multitude of different ways. These findings have implications for the prioritizing...... of TDP contents and activities and also suggest new avenues for exploring how quality student learning relates to teacher development....

  11. Planetary protection R&D activities in the ESA exploration programme

    Science.gov (United States)

    Kminek, G.

    Since the begin of the Aurora exploration programme in 2001 the Human Spaceflight Microgravity and Exploration Directorate HME of ESA has invested in research and development activities related to planetary protection Some of these activities are focused on the recently approved ExoMars mission others are applicable to Mars missions in general including MSR the technology development of the latter one being part of the exploration core programme The proposed activities have been approved and initiated An overview of the activities and first results will be presented The main activities are begin itemize item Bioburden and Biodiversity evaluation in S C Facilities this activity will cover a period of almost two years and include the standard assay extension of the standard assay culture conditions identification of isolates using 16S rDNA via PCR and test of a rapid spore assay Protocols are developed in coordination with NASA-JPL item Extension of dry heat microbial reduction process to higher temperatures this activity will include a detailed study of the humidity effect on the inactivation kinetics This activity is in coordination with efforts at NASA-JPL item Validation of a dry heat sterilization process item Development of a low-temperature sterilization method the focus of this activity is on vapor hydrogen peroxide item Robotic capabilities for clean AIV AIT item Decontamination of man-rated systems item Definition of functional requirements for a Mars Sample Return Biological Containment Facility end itemize In

  12. Active surveillance and control programme for Salmonella Dublin in Cattle

    DEFF Research Database (Denmark)

    Nielsen, Liza Rosenbaum; Rattenborg, Erik

    2011-01-01

    surveillance systems. Register data might be useful for design of effective surveillance programmes for Salmonella Dublin in cattle in the future. Statistical analysis of register-based variables confirmed previously known risk factors for becoming test-positive (i.e. purchase of animals from test......This study illustrates how prevalence and incidence of Salmonella Dublin in cattle has been markedly reduced in dairy herds during active surveillance and a control programme targeting infected herds in Denmark from 2002 to 2010. The results suggest that this might by a good alternative to passive......-positive herds, number of cattle in test-positive neighbouring herds, herd size and season), but also pointed out additional factors affecting the risk of dairy herds changing status from test-negative to test-positive (indicative of new or recurrent infection). Increasing geometric cell count measured through...

  13. Evaluation of Activities in Primary Education Programme with The Teachers’ Views (Sample of Sinop Province

    Directory of Open Access Journals (Sweden)

    Necdet AYKAÇ

    2007-12-01

    Full Text Available This research, aims to investigate the concept of activity on the basis of learning-teaching duration inaccordance with teachers’ views, teachers guide and class materials in the primary education programme put in to practice in 2005- 2006. The research has two subjects. The first one is the quantitative subject aiming to determine the teachers’ views, the second is theoretical subject aiming to analyze the guide books and class metarials. The quantitative research, aiming to determine the teachers’ ideas is consisted of 184 teachers in total in the center and in the central villages of Sinop. The exemplification in this research is occupied by means of 86 teachers applying the teachers’ views determinating scale. In the research as a tool to collect data, determining teachers’ views scale prepared in 5 likert-type scale with 18 articles has been used. Analyzing with SPSS programme, the data gained from the scale has been stated as frequency and percentage. Theoretical dimension examining teachers’ guide and lesson metarials to put the teachers’ views on a objective base, aims to examine teachers guide books and lesson materials analytically and display the base of teachers’ views. It is stated that most of the teachers present their views in that way: They feel themselves insufficent to applythe activities,the physical opportunities of the schools and the facilities are not enough to apply some activities, the classes are crowded, the activities are not student-centered and active teaching methods are not used in the activities.

  14. Talking Techne: Techniques to Establish an Active Online Discussion Forum

    Science.gov (United States)

    Palenque, Stephanie Maher; DeCosta, Meredith

    2015-01-01

    Discussion forums are critically important to the online classroom, as they virtually take the place of a classroom discussion and become a stage on which active learning takes place. Active learning occurs when instructors practice certain techniques in the discussion that are carefully and thoughtfully crafted and guided. The authors propose the…

  15. Effects of a physical activity programme on body perception and composition in overweight adolescents

    Directory of Open Access Journals (Sweden)

    Onofre Ricardo Contreras-Jordán

    2017-03-01

    Full Text Available Background The purpose of this study was to examine the effectiveness of a six months' physical activity programme for overweight and obese adolescents, in order to improve the perception of their own body image and composition between two groups of adolescents, and to check possible gender differences. Aims The aim is to improve the body perception and composition in overweight adolescents with a physical activity programme. Methods It was a quasi-experimental design, with a control group and intervention group. Measures of pre-test and post-test were taken. A total of 38 adolescents that belong to the first cycle of Compulsory Secondary aged 12–15, with a body mass index (BMI higher than the 85th percentile according to the WHO (World Health Organization, participated in the intervention. The anthropometric variables, height, weight, BMI, body fat percentage, and the circumference of the waist, hip, arm and medial calf, were measured pre- and post-treatment. The body image perception was measured using the Gardner test. The experimental group participated in the physical activity programme for a six months period. The physical activity intervention consisted of three sessions of 90 minutes each week in a sports centre. The structure of the sessions consisted of a warm-up (5–10 minutes, a main activity (60–70 minutes, combineding strength and cardiovascular training and a cool-down (7–10 minutes. Results After physical activity intervention the results showed significant improvements in the experimental group compared to the control group in the circumference of the waist, the hip, the arm, the medial calf (p<0.01 and as well as the fat percentage, the percentage of muscle mass (p<0.05. The results showed how the body image distortion presented a significant and negative correlation with the circumference of the waist (p<0.001, of the hips (p<0.01, and of the arm (p<0.001, differences were observed between gender. Conclusion Our study

  16. [Effect of a physical activity programme in patients with fibromyalgia: a systematic review].

    Science.gov (United States)

    Cadenas-Sánchez, Cristina; Ruiz-Ruiz, Jonatan

    2014-12-23

    The aim of this review was to determine what type of physical activity programmes have been developed in patients with fibromyalgia and what are its effects and benefits on the degree of pain and quality of life. The search was performed in MEDLINE, Web of Science and SPORTDiscus databases. The word "fibromyalgia" was always used as a criterion for combined search (using "AND" connector) with physical activity, exercise, physical therapy and training (MeSH terms). Of the 2,531 initial results, 33 papers were selected for review. The studies reviewed focus primarily on dance activities, water activities, multidisciplinary, mind-body work, fitness and stretching. After applying the intervention program, the pain level was reduced between 10 and 44.2%, and the impact of the disease between 5.3 and 17.9%, improving the symptoms of these patients. In conclusion, a multidisciplinary programme (in which physical activity is included) may have positive effects on the quality of life of people with fibromyalgia. Copyright © 2013 Elsevier España, S.L.U. All rights reserved.

  17. Established and emerging biological activity markers of inflammatory bowel disease

    DEFF Research Database (Denmark)

    Nielsen, O H; Vainer, B; Madsen, S M;

    2000-01-01

    Assessment of disease activity in inflammatory bowel disease (IBD), i.e., ulcerative colitis (UC) and Crohn's disease (CD), is done using clinical parameters and various biological disease markers. Ideally, a disease marker must: be able to identify individuals at risk of a given disorder...... molecules. It is concluded that none of the pertinent laboratory surrogate markers of disease activity in IBD are specific or sensitive enough to replace basic clinical observation such as the number of daily bowel movements, general well-being, and other parameters in parallel. Further studies are highly...... warranted to identify and assess the clinical importance and applicability of new laboratory markers for the diagnosis or the disease activity of IBD....

  18. Established and emerging biological activity markers of inflammatory bowel disease

    DEFF Research Database (Denmark)

    Nielsen, O H; Vainer, B; Madsen, S M;

    2000-01-01

    Assessment of disease activity in inflammatory bowel disease (IBD), i.e., ulcerative colitis (UC) and Crohn's disease (CD), is done using clinical parameters and various biological disease markers. Ideally, a disease marker must: be able to identify individuals at risk of a given disorder......, be disease specific, mirror the disease activity and, finally, be easily applicable for routine clinical purposes. However, no such disease markers have yet been identified for IBD. In this article, classical disease markers including erythrocyte sedimentation rate, acute phase proteins (especially...

  19. Objects prompt authentic scientific activities among learners in a museum programme

    DEFF Research Database (Denmark)

    Achiam, Marianne; Simony, Leonora; Lindow, Bent Erik Kramer

    2016-01-01

    Although the scientific disciplines conduct practical work in different ways, all consider practical work as the essential way of connecting objects and phenomena with ideas and the abstract. Accordingly, practical work is regarded as central to science education as well. We investigate a practical......, object-based palaeontology programme at a natural history museum to identify how palaeontological objects prompt scientific activity among upper secondary school students. We first construct a theoretical framework based on an analysis of the programme’s palaeontological content. From this, we build our...... are palaeontologically authentic. Finally, we discuss our findings, examining the mechanism by which the specimens prompt scientific activities. We also discuss our discipline-based approach, and how it allows us to positively identify participants’ activities as authentic. We conclude by discussing the implications...

  20. The ProActive trial protocol – a randomised controlled trial of the efficacy of a family-based, domiciliary intervention programme to increase physical activity among individuals at high risk of diabetes [ISRCTN61323766

    Directory of Open Access Journals (Sweden)

    Ekelund Ulf

    2004-10-01

    Full Text Available Abstract Background Increasing prevalence of obesity and disorders associated with sedentary living constitute a major global public health problem. While previous evaluations of interventions to increase physical activity have involved communities or individuals with established disease, less attention has been given to interventions for individuals at risk of disease. Methods/design ProActive aims to evaluate the efficacy of a theoretical, evidence- and family-based intervention programme to increase physical activity in a sedentary population, defined as being at-risk through having a parental family history of diabetes. Primary care diabetes or family history registers were used to recruit 365 individuals aged 30–50 years, screened for activity level. Participants were assigned by central randomisation to three intervention programmes: brief written advice (comparison group, or a psychologically based behavioural change programme, delivered either by telephone (distance group or face-to-face in the family home over one year. The protocol-driven intervention programme is delivered by trained facilitators, and aims to support increases in physical activity through the introduction and facilitation of a range of self-regulatory skills (e.g. goal setting. The primary outcome is daytime energy expenditure and its ratio to resting energy expenditure, measured at baseline and one year using individually calibrated heart rate monitoring. Secondary measures include self-report of individual and family activity, psychological mediators of behaviour change, physiological and biochemical correlates, acceptability, and costs, measured at baseline, six months and one year. The primary intention to treat analysis will compare groups at one-year post randomisation. Estimation of the impact on diabetes incidence will be modelled using data from a parallel ten-year cohort study using similar measures. Discussion ProActive is the first efficacy trial of an

  1. Physical activity on prescription schemes (PARS): do programme characteristics influence effectiveness? Results of a systematic review and meta-analyses

    Science.gov (United States)

    Arsenijevic, Jelena; Groot, Wim

    2017-01-01

    Background Physical activity on prescription schemes (PARS) are health promotion programmes that have been implemented in various countries. The aim of this study was to outline the differences in the design of PARS in different countries. This study also explored the differences in the adherence rate to PARS and the self-reported level of physical activity between PARS users in different countries. Method A systematic literature review and meta-analyses were conducted. We searched PubMed and EBASCO in July 2015 and updated our search in September 2015. Studies that reported adherence to the programme and self-reported level of physical activity, published in the English language in a peer-reviewed journal since 2000, were included. The difference in the pooled adherence rate after finishing the PARS programme and the adherence rate before or during the PARS programme was 17% (95% CI 9% to 24%). The difference in the pooled physical activity was 0.93 unit score (95 CI −3.57 to 1.71). For the adherence rate, a meta-regression was conducted. Results In total, 37 studies conducted in 11 different countries met the inclusion criteria. Among them, 31 reported the adherence rate, while the level of physical activity was reported in 17 studies. Results from meta-analyses show that PARS had an effect on the adherence rate of physical activity, while the results from the meta-regressions show that programme characteristics such as type of chronic disease and the follow-up period influenced the adherence rate. Conclusions The effects of PARS on adherence and self-reported physical activity were influenced by programme characteristics and also by the design of the study. Future studies on the effectiveness of PARS should use a prospective longitudinal design and combine quantitative and qualitative data. Furthermore, future evaluation studies should distinguish between evaluating the adherence rate and the self-reported physical activity among participants with different

  2. Active Labour Market Programme Participation for Unemployment Insurance Recipients: A Systematic Review

    DEFF Research Database (Denmark)

    Filges, Trine; Smedslund, Geir; Knudsen, Anne-Sofie Due

    2015-01-01

    , subsequently, their employability. Other ALMPs are designed to encourage the unemployed to return to work. Typically, compulsory programme participation is required after the individual has received unemployment benefits for a certain period of time. A large variety of different ALMPs exist among countries....... They can consist of job search assistance, training, education, subsidized work and similar programmes. Some of the programmes (such as subsidized work, training and education) demand full-time participation over a long time period (e.g. several months), while other programmes (such as job search...... assistance and education) are part-time and have a short duration (e.g. few days/weeks). It is possible to classify these programmes into a set of four core categories: A: (labour market) training, B: Private sector programmes, C: direct employment programmes in the public sector and D: Job search assistance...

  3. MATHEMATICAL OPTIMIZATION METHODS TO ESTABLISH ACTIVE PHASES ON HETEROGENEOUS CATALYSIS: CASE OF BULK TRANSITION METAL SULPHIDES

    Directory of Open Access Journals (Sweden)

    Iván Machín

    2015-03-01

    Full Text Available This paper presents a set of procedures based on mathematical optimization methods to establish optimal active sulphide phases with higher HDS activity. This paper proposes a list of active phases as a guide for orienting the experimental work in the search of new catalysts that permit optimize the HDS process. Studies in this paper establish Co-S, Cr-S, Nb-S and Ni-S systems have the greatest potential to improve HDS activity.

  4. Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9.

    Science.gov (United States)

    Koo, Taeyoung; Lee, Jungjoon; Kim, Jin-Soo

    2015-06-01

    Programmable nucleases, which include zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and RNA-guided engineered nucleases (RGENs) repurposed from the type II clustered, regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9) system are now widely used for genome editing in higher eukaryotic cells and whole organisms, revolutionising almost every discipline in biological research, medicine, and biotechnology. All of these nucleases, however, induce off-target mutations at sites homologous in sequence with on-target sites, limiting their utility in many applications including gene or cell therapy. In this review, we compare methods for detecting nuclease off-target mutations. We also review methods for profiling genome-wide off-target effects and discuss how to reduce or avoid off-target mutations.

  5. Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins.

    Science.gov (United States)

    Maeder, Morgan L; Angstman, James F; Richardson, Marcy E; Linder, Samantha J; Cascio, Vincent M; Tsai, Shengdar Q; Ho, Quan H; Sander, Jeffry D; Reyon, Deepak; Bernstein, Bradley E; Costello, Joseph F; Wilkinson, Miles F; Joung, J Keith

    2013-12-01

    Genome-wide studies have defined cell type-specific patterns of DNA methylation that are important for regulating gene expression in both normal development and disease. However, determining the functional significance of specific methylation events remains challenging, owing to the lack of methods for removing such modifications in a targeted manner. Here we describe an approach for efficient targeted demethylation of specific CpGs in human cells using fusions of engineered transcription activator-like effector (TALE) repeat arrays and the TET1 hydroxylase catalytic domain. Using these TALE-TET1 fusions, we demonstrate that modification of critical methylated promoter CpG positions can lead to substantial increases in the expression of endogenous human genes. Our results delineate a strategy for understanding the functional significance of specific CpG methylation marks in the context of endogenous gene loci and validate programmable DNA demethylation reagents with potential utility for research and therapeutic applications.

  6. The SEDIBUD (Sediment Budgets in Cold Environments) Programme: Current activities and future key tasks

    Science.gov (United States)

    Beylich, A. A.; Lamoureux, S. F.; Decaulne, A.

    2012-04-01

    Projected climate change in cold regions is expected to alter melt season duration and intensity, along with the number of extreme rainfall events, total annual precipitation and the balance between snowfall and rainfall. Similarly, changes to the thermal balance are expected to reduce the extent of permafrost and seasonal ground frost and increase active layer depths. These effects will undoubtedly change surface environments in cold regions and alter the fluxes of sediments, nutrients and solutes, but the absence of quantitative data and coordinated process monitoring and analysis to understand the sensitivity of the Earth surface environment is acute in cold climate environments. The International Association of Geomorphologists (I.A.G./A.I.G.)SEDIBUD (Sediment Budgets in Cold Environments) Programme was formed in 2005 to address this existing key knowledge gap. SEDIBUD currently has about 400 members worldwide and the Steering Committee of this international programme is composed of ten scientists from eight different countries: Achim A. Beylich (Chair) (Norway), Armelle Decaulne (Secretary) (France), John C. Dixon (USA), Scott F. Lamoureux (Vice-Chair) (Canada), John F. Orwin (Canada), Jan-Christoph Otto (Austria), Irina Overeem (USA), Thorsteinn Saemundsson (Iceland), Jeff Warburton (UK), Zbigniew Zwolinski (Poland). The central research question of this global group of scientists is to: Assess and model the contemporary sedimentary fluxes in cold climates, with emphasis on both particulate and dissolved components. Initially formed as European Science Foundation (ESF) Network SEDIFLUX (2004-2006), SEDIBUD has further expanded to a global group of researchers with field research sites located in polar and alpine regions in the northern and southern hemisphere. Research carried out at each of the close to 50 defined SEDIBUD key test sites varies by programme, logistics and available resources, but typically represent interdisciplinary collaborations of

  7. Re-thinking global health sector efforts for HIV and tuberculosis epidemic control: promoting integration of programme activities within a strengthened health system

    Directory of Open Access Journals (Sweden)

    Maher Dermot

    2010-07-01

    Full Text Available Abstract Background The global financial crisis threatens global health, particularly exacerbating diseases of inequality, e.g. HIV/AIDS, and diseases of poverty, e.g. tuberculosis. The aim of this paper is to reconsider established practices and policies for HIV and tuberculosis epidemic control, aiming at delivering better results and value for money. This may be achieved by promoting greater integration of HIV and tuberculosis control programme activities within a strengthened health system. Discussion HIV and tuberculosis share many similarities in terms of their disease burden and the recommended stratagems for their control. HIV and tuberculosis programmes implement similar sorts of control activities, e.g. case finding and treatment, which depend for success on generic health system issues, including vital registration, drug procurement and supply, laboratory network, human resources, and financing. However, the current health system approach to HIV and tuberculosis control often involves separate specialised services. Despite some recent progress, collaboration between the programmes remains inadequate, progress in obtaining synergies has been slow, and results remain far below those needed to achieve universal access to key interventions. A fundamental re-think of the current strategic approach involves promoting integrated delivery of HIV and tuberculosis programme activities as part of strengthened general health services: epidemiological surveillance, programme monitoring and evaluation, community awareness of health-seeking behavior, risk behaviour modification, infection control, treatment scale-up (first-line treatment regimens, drug-resistance surveillance, containing and countering drug-resistance (second-line treatment regimens, research and development, global advocacy and global partnership. Health agencies should review policies and progress in HIV and tuberculosis epidemic control, learn mutual lessons for policy

  8. A primary school active break programme (ACTI-BREAK): study protocol for a pilot cluster randomised controlled trial.

    Science.gov (United States)

    Watson, Amanda; Timperio, Anna; Brown, Helen; Hesketh, Kylie D

    2017-09-19

    Levels of overall physical activity have been shown to decline across childhood. Schools are considered ideal settings to promote physical activity as children spend a large amount of their waking hours at school. Time-efficient physical activity strategies that demonstrate a positive impact on academic-related outcomes are needed to enable physical activity to be prioritised in the school day. The ACTI-BREAK programme requires classroom teachers to integrate active breaks; 5-min bursts of moderate-intensity physical activity into their classroom routine. Active breaks have been shown to be effective in improving academic-related outcomes, a potentially appealing aspect for teachers and schools. The primary aim of this study is to assess the feasibility and potential efficacy of the ACTI-BREAK programme on children's academic achievement. Secondary aims are to explore the impact of ACTI-BREAK on children's on-task behaviour and objectively measured physical activity levels. ACTI-BREAK is a 6-week, classroom-based, physical activity intervention. This pilot trial of the programme will be evaluated using a cluster randomised controlled design. Government primary schools in metropolitan Melbourne, Australia will be invited to participate in the programme in 2017. Randomisation will occur at the school level, with the aim to recruit six schools (three intervention and three control). The ACTI-BREAK programme is theoretically grounded, and was developed with input and guidance from current primary school teachers. Teachers from the intervention schools will receive a 45-min training session and be asked to incorporate ACTI-BREAKS into their classroom routine three times per day for 6 weeks. Intervention support will be provided via assisted delivery. The primary outcomes will be children's academic achievement in mathematics and reading. Children's on-task behaviour and school-day physical activity will be assessed as secondary outcomes. Process evaluation will also be

  9. A multichannel integrated circuit for electrical recording of neural activity, with independent channel programmability.

    Science.gov (United States)

    Mora Lopez, Carolina; Prodanov, Dimiter; Braeken, Dries; Gligorijevic, Ivan; Eberle, Wolfgang; Bartic, Carmen; Puers, Robert; Gielen, Georges

    2012-04-01

    Since a few decades, micro-fabricated neural probes are being used, together with microelectronic interfaces, to get more insight in the activity of neuronal networks. The need for higher temporal and spatial recording resolutions imposes new challenges on the design of integrated neural interfaces with respect to power consumption, data handling and versatility. In this paper, we present an integrated acquisition system for in vitro and in vivo recording of neural activity. The ASIC consists of 16 low-noise, fully-differential input channels with independent programmability of its amplification (from 100 to 6000 V/V) and filtering (1-6000 Hz range) capabilities. Each channel is AC-coupled and implements a fourth-order band-pass filter in order to steeply attenuate out-of-band noise and DC input offsets. The system achieves an input-referred noise density of 37 nV/√Hz, a NEF of 5.1, a CMRR > 60 dB, a THD < 1% and a sampling rate of 30 kS/s per channel, while consuming a maximum of 70 μA per channel from a single 3.3 V. The ASIC was implemented in a 0.35 μm CMOS technology and has a total area of 5.6 × 4.5 mm². The recording system was successfully validated in in vitro and in vivo experiments, achieving simultaneous multichannel recordings of cell activity with satisfactory signal-to-noise ratios.

  10. Indian Solar Cities Programme: An Overview of Major Activities and Accomplishments; Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Kandt, A.

    2012-05-01

    This paper details the Indian Solar City Programme, provides an overview of one city's Master Plan and implementation progress, describes NREL's support of the Indian Solar City Programme, and outlines synergies and differences between the Indian and American programs including unique challenges and opportunities India is facing.

  11. Decrease in heart rate after longitudinal participation in the Groningen Active Living Model (GALM) recreational sports programme

    NARCIS (Netherlands)

    de Jong, Johan; Lemmink, Koen; Scherder, Erik; Stewart, Roy; King, Abby; Stevens, Martin

    2009-01-01

    The aim of this study was to investigate changes in heart rate during submaximal exercise as an index of cardiovascular function in older adults participating in the Groningen Active Living Model recreational sports programme who were sedentary or underactive at baseline. A repeated measurement desi

  12. Short- and long-term effects of a physical activity counselling programme in COPD : A randomized controlled trial

    NARCIS (Netherlands)

    Altenburg, Wytske A.; ten Hacken, Nick H. T.; Bossenbroek, Linda; Kerstjens, Huib A. M.; de Greef, Mathieu H.G.; Wempe, Johan B.

    2015-01-01

    Background: We were interested in the effects of a physical activity (PA) counselling programme in three groups of COPD patients from general practice (primary care), outpatient clinic (secondary care) and pulmonary rehabilitation (PR). Methods: In this randomized controlled trial 155 COPD patients,

  13. Decrease in heart rate after longitudinal participation in the Groningen Active Living Model (GALM) recreational sports programme

    NARCIS (Netherlands)

    de Jong, Johan; Lemmink, Koen; Scherder, Erik; Stewart, Roy; King, Abby; Stevens, Martin

    2009-01-01

    The aim of this study was to investigate changes in heart rate during submaximal exercise as an index of cardiovascular function in older adults participating in the Groningen Active Living Model recreational sports programme who were sedentary or underactive at baseline. A repeated measurement

  14. Longitudinal changes in heart rate after participating in the Groningen Active Living Model (GALM) recreational sports programme

    NARCIS (Netherlands)

    Erik Scherder; Abby King; Roy Stewart; Dr. Johan de Jong; Koen A.P.M. Lemmink

    2009-01-01

    The aim of this study was to investigate changes in heart rate during submaximal exercise as an index of cardiovascular function in older adults participating in the Groningen Active Living Model recreational sports programme who were sedentary or underactive at baseline. A repeated measurement

  15. Sexual activity as a trigger of myocardial infarction. A case-crossover analysis in the Stockholm Heart Epidemiology Programme (SHEEP)

    DEFF Research Database (Denmark)

    Möller, J; Ahlbom, A; Hulting, J

    2001-01-01

    OBJECTIVE: To investigate sexual activity as a trigger of myocardial infarction and the potential effect modification of physical fitness. DESIGN: A case-crossover study nested in the Stockholm Heart Epidemiology Programme (SHEEP). SETTING: Stockholm County from April 1993 to December 1994...

  16. From Passive to Active Learners: The "Lived Experience" of Nurses in a Specialist Nephrology Nursing Education Programme

    Science.gov (United States)

    Bridger, Jane

    2007-01-01

    Purpose: This study aims to explore the lived experience of learning for a group of staff nurses in the Middle East, who undertook a post-registration nursing education programme in the speciality of nephrology nursing (the NNP) between 2001 and 2002. The broad-based curriculum seeks to develop the staff nurses into active learners, able to…

  17. Care of older people in nursing homes: an Intensive Programme as an educational activity within Erasmus-Socrates.

    Science.gov (United States)

    Kotzabassaki, Stella; Alabaster, Erica S; And, Kati; Larsson, Ulla; de Vree, Willem

    2003-02-01

    The paper describes and discusses an Intensive Programme as a European educational activity within Erasmus-Socrates. As nurses and European citizens, it is important to know and understand each other's culture and to be able to work within a united Europe. Education plays a leading role in the preparation of professionals who will have to develop these skills. Based on the aims of Erasmus-Socrates, an Intensive Programme entitled 'Care of Older People in Nursing Homes' was designed, sponsored, and implemented over three continuous academic years with the participation of five European countries. The topic was selected due to its importance for Europe, as it is a region with an ageing population. A wide range of themes was covered using lectures, group discussion, exercises and study visits as teaching strategies. Evaluation suggests that the aims of the programme were achieved.

  18. Hardware Activation by Means of PUFs and Elliptic Curve Cryptography in Field-Programmable Devices

    Directory of Open Access Journals (Sweden)

    Luis Parrilla

    2016-01-01

    Full Text Available Reusable design using IP cores requires of efficient methods for protecting the Intellectual Property of the designer and the corresponding license agreements. In this work, a new protection procedure establishing an activation protocol in a similar way to the activation process in the software world is presented. The procedure, named SEHAS (Secure Hardware Activation System allows the distribution of cores in either Blocked (not functioning or Demo (functioning with limited features modes, while ensuring the license agreements by identifying not only the IP core but also the implementation device, using Physically Unclonable Functions (PUF. Moreover, SEHAS secures the exchange of information between the core and the core vendor using an Elliptic Curve Cryptosystem (ECC. This secure channel allows the IP core vendor to send a unique Activation Code to the core in order to switch it to the Activated Mode, thus enabling all its features.

  19. Establishment and evolution of Radiological Environmental Monitoring Programmes in nuclear power plants; Establecimiento y evolucion de los programas de vigilancia radiologica ambiental en las centrales nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Marugan, I.; Luque, S.; Martin, J. L.; Rey, C.; Salas, R.; Sterling, A.; Ramos, L. M.

    2013-09-01

    This article presents a brief overview of how the Radiological Environmental Monitoring Programmes carried out around nuclear power plants have evolved associated to different reasons as the legal framework, operational phases of the facilities, development on the detection and measurement of low levels of radiation due to the state of art and best available technologies, changes within sites as well as in their surroundings and accident taken place inside and outside of our borders. (Author)

  20. A Structured Physical Activity and Fitness Programme for Older Adults with Intellectual Disabilities: Results of a Cluster-Randomised Clinical Trial

    Science.gov (United States)

    van Schijndel-Speet, M.; Evenhuis, H. M.; van Wijck, R.; van Montfort, K. C. A. G. M.; Echteld, M. A.

    2017-01-01

    Background: The physical activity level of older adults with intellectual disabilities (ID) is extremely low, and their fitness levels are far beneath accepted norms for older people with normal intelligence and comparable with frail older people. A physical activity programme, including an education programme, was developed for older adults with…

  1. A Structured Physical Activity and Fitness Programme for Older Adults with Intellectual Disabilities: Results of a Cluster-Randomised Clinical Trial

    Science.gov (United States)

    van Schijndel-Speet, M.; Evenhuis, H. M.; van Wijck, R.; van Montfort, K. C. A. G. M.; Echteld, M. A.

    2017-01-01

    Background: The physical activity level of older adults with intellectual disabilities (ID) is extremely low, and their fitness levels are far beneath accepted norms for older people with normal intelligence and comparable with frail older people. A physical activity programme, including an education programme, was developed for older adults with…

  2. Technology Programme

    Energy Technology Data Exchange (ETDEWEB)

    Batistoni, Paola; De Marco, Francesco; Pieroni, Leonardo (ed.)

    2005-07-01

    The technology activities carried out by the Euratom-ENEA Association in the framework of the European Fusion Development Agreement concern the Next Step (International Thermonuclear Experimental Reactor - ITER), the Long-Term Programme (breeder blanket, materials, International Fusion Materials Irradiation Facility - IFMIF), Power Plant Conceptual Studies and Socio-Economic Studies. The Underlying Technology Programme was set up to complement the fusion activities as well to develop technologies with a wider range of interest. The Technology Programme mainly involves staff from the Frascati laboratories of the Fusion Technical and Scientific Unit and from the Brasimone laboratories of the Advanced Physics Technologies Unit. Other ENEA units also provide valuable contributions to the programme. ENEA is heavily engaged in component development/testing and in design and safety activities for the European Fusion Technology Programme. Although the work documented in the following covers a large range of topics that differ considerably because they concern the development of extremely complex systems, the high level of integration and coordination ensures the capability to cover the fusion system as a whole. In 2004 the most significant testing activities concerned the ITER primary beryllium-coated first wall. In the field of high-heat-flux components, an important achievement was the qualification of the process for depositing a copper liner on carbon fibre composite (CFC) hollow tiles. This new process, pre-brazed casting (PBC), allows the hot radial pressing (HRP) joining procedure to be used also for CFC-based armour monoblock divertor components. The PBC and HRP processes are candidates for the construction of the ITER divertor. In the materials field an important milestone was the commissioning of a new facility for chemical vapour infiltration/deposition, used for optimising silicon carbide composite (SiCf/SiC) components. Eight patents were deposited during 2004

  3. SET-Routes programme

    CERN Document Server

    CERN audiovisual service

    2009-01-01

    The SET-Routes programme, launched in 2007 with the goal of attracting girls and young women to careers in science, came to an end in April this year. The result of a collaboration between EMBL, EMBO and CERN, the programme established a network of "ambassadors", women scientists who went out to talk about their careers in science at schools and universities across Europe.

  4. A programmable broadband low frequency active vibration isolation system for atom interferometry

    Science.gov (United States)

    Tang, Biao; Zhou, Lin; Xiong, Zongyuan; Wang, Jin; Zhan, Mingsheng

    2014-09-01

    Vibration isolation at low frequency is important for some precision measurement experiments that use atom interferometry. To decrease the vibrational noise caused by the reflecting mirror of Raman beams in atom interferometry, we designed and demonstrated a compact stable active low frequency vibration isolation system. In this system, a digital control subsystem is used to process and feedback the vibration measured by a seismometer. A voice coil actuator is used to control and cancel the motion of a commercial passive vibration isolation platform. With the help of field programmable gate array-based control subsystem, the vibration isolation system performed flexibly and accurately. When the feedback is on, the intrinsic resonance frequency of the system will change from 0.8 Hz to about 0.015 Hz. The vertical vibration (0.01-10 Hz) measured by the in-loop seismometer is reduced by an additional factor of up to 500 on the basis of a passive vibration isolation platform, and we have proved the performance by adding an additional seismometer as well as applying it in the atom interferometry experiment.

  5. A programmable broadband low frequency active vibration isolation system for atom interferometry.

    Science.gov (United States)

    Tang, Biao; Zhou, Lin; Xiong, Zongyuan; Wang, Jin; Zhan, Mingsheng

    2014-09-01

    Vibration isolation at low frequency is important for some precision measurement experiments that use atom interferometry. To decrease the vibrational noise caused by the reflecting mirror of Raman beams in atom interferometry, we designed and demonstrated a compact stable active low frequency vibration isolation system. In this system, a digital control subsystem is used to process and feedback the vibration measured by a seismometer. A voice coil actuator is used to control and cancel the motion of a commercial passive vibration isolation platform. With the help of field programmable gate array-based control subsystem, the vibration isolation system performed flexibly and accurately. When the feedback is on, the intrinsic resonance frequency of the system will change from 0.8 Hz to about 0.015 Hz. The vertical vibration (0.01-10 Hz) measured by the in-loop seismometer is reduced by an additional factor of up to 500 on the basis of a passive vibration isolation platform, and we have proved the performance by adding an additional seismometer as well as applying it in the atom interferometry experiment.

  6. Programmes of measures under the water framework directive – a comparative case study

    DEFF Research Database (Denmark)

    Baaner, Lasse

    2011-01-01

    direct the authorities’ activities with regard to water management. It concludes that there are major differences in the precision of the measures, the range of legal instruments used, and in the focus on active and direct management of the aquatic environment. The Danish programme seems to facilitate...... the establishment of an adaptive management, whereas the Swedish and Norwegian programmes seem to take a more integrative approach.......The water framework directive requires programmes of measures composed by the Member States, in order to achieve its environmental objectives. This article examines three programmes of measures for river basins in Denmark, Sweden, and Norway, with a focus on the differences in how the programmes...

  7. The Impact of Adventure Based Activity at Malaysian National Service Training Programme on Team Cohesion: A Demographic Analysis.

    Directory of Open Access Journals (Sweden)

    Jaffry Zakaria

    2012-12-01

    Full Text Available The present study examines the effects of physical module elements (adventure based activity included in the Malaysian National Service Programme and to investigate the socio-demographic variables impact on team cohesion building among the participants. In this study, the participants were selected from three different camps, namely, Tasoh camp, Guar Chenderai camp and Meranti camp, located in the state of Perlis, Malaysia. The participants were those from the second batch intake in the year 2007. The sample sizes comprised of 994 participants (480=males, 514=females. The present study applied a pre-test and post-test design. The group was tested before and after the programme. This design was chosen because it could measure the impacts of the adventure-based activity towards team cohesion over time through the pre- and post-test scores (Berg & Latin, 2004. The variables comprised of the demographic factors (age, gender and place of residence, which included team cohesion were measured by Group Environmental Questionnaire (GEQ (Carron, Widmeyer, & Brawley, 1985. Results indicated that the participants of the National Service Training Programme underwent group cohesion change during the Physical Module activities (adventure based activities that were carried out at the camp. The changes were observable based on the statistically analyzed data during the pre and post-test.

  8. Developmental programming of energy balance regulation: is physical activity more 'programmable' than food intake?

    Science.gov (United States)

    Zhu, Shaoyu; Eclarinal, Jesse; Baker, Maria S; Li, Ge; Waterland, Robert A

    2016-02-01

    Extensive human and animal model data show that environmental influences during critical periods of prenatal and early postnatal development can cause persistent alterations in energy balance regulation. Although a potentially important factor in the worldwide obesity epidemic, the fundamental mechanisms underlying such developmental programming of energy balance are poorly understood, limiting our ability to intervene. Most studies of developmental programming of energy balance have focused on persistent alterations in the regulation of energy intake; energy expenditure has been relatively underemphasised. In particular, very few studies have evaluated developmental programming of physical activity. The aim of this review is to summarise recent evidence that early environment may have a profound impact on establishment of individual propensity for physical activity. Recently, we characterised two different mouse models of developmental programming of obesity; one models fetal growth restriction followed by catch-up growth, and the other models early postnatal overnutrition. In both studies, we observed alterations in body-weight regulation that persisted to adulthood, but no group differences in food intake. Rather, in both cases, programming of energy balance appeared to be due to persistent alterations in energy expenditure and spontaneous physical activity (SPA). These effects were stronger in female offspring. We are currently exploring the hypothesis that developmental programming of SPA occurs via induced sex-specific alterations in epigenetic regulation in the hypothalamus and other regions of the central nervous system. We will summarise the current progress towards testing this hypothesis. Early environmental influences on establishment of physical activity are likely an important factor in developmental programming of energy balance. Understanding the fundamental underlying mechanisms in appropriate animal models will help determine whether early life

  9. [Self-management programme for leg ulcer patients: increased physical activity and fewer wound days

    NARCIS (Netherlands)

    Heinen, M.M.; Borm, G.F.; Vleuten, C.J. van der; Evers, A.W.; Oostendorp, R.A.B.; Achterberg, T. van

    2012-01-01

    OBJECTIVE: To investigate the effectiveness of the Lively Legs programme on patient adherence to compression therapy, walking behaviour and leg exercising, as well as on leg ulcer recurrence. DESIGN: Randomized controlled trial (ClinicalTrials.gov identifier: NCT00184873). METHOD: A total of 184 pat

  10. Active surveillance and control programme for Salmonella Dublin in Cattle

    DEFF Research Database (Denmark)

    Nielsen, Liza Rosenbaum; Rattenborg, Erik

    2011-01-01

    -positive. This suggests that there might be synergistic benefits from running control programmes for both infections simultaneously. We did not find the risk of becoming test-positive significantly different between organic and conventional herds, nor between analysing laboratories. Even when controlling for other risk...

  11. The CERN & Society programme launches its newsletter

    CERN Multimedia

    Matteo Castoldi

    2016-01-01

    The newsletter will be issued quarterly. Sign up to remain informed about the latest initiatives of the CERN & Society programme!    The CERN & Society programme encompasses projects in the areas of education and outreach, innovation and knowledge exchange, and culture and creativity that spread the CERN spirit of scientific curiosity for the inspiration and benefit of society. The programme is funded primarily by the CERN & Society Foundation, a charitable foundation established by CERN and supported by individuals, trusts, organisations and commercial companies. The projects are inspired or enabled by CERN but lie outside of the Laboratory’s specific research mandate. We especially want to help young talent from around the world to flourish in the future. The programme is now launching its newsletter, which will be issued quarterly. Everybody who wants to be informed about CERN & Society’s activities, stay up-to-date with its latest in...

  12. The UNESCO Bioethics Programme: a review.

    Science.gov (United States)

    Langlois, Adéle

    2014-01-01

    UNESCO's Bioethics Programme was established in 1993. In twenty years it has adopted three international declarations, on the human genome (1997), human genetic data (2003) and bioethics (2005); produced reports on a wide range of bioethics issues; and developed capacity building and public education programmes in bioethics. Yet UNESCO has sometimes struggled to assert its authority in the wider bioethics world. Some bioethicists have criticized the 2005 declaration and suggested that the World Health Organization might be better placed to advance bioethics. In 2011, after four years of debate, UNESCO decided not to draft a convention on human reproductive cloning, because consensus on the issue proved impossible. This article reviews the standard setting and capacity building activities of the UNESCO Bioethics Programme. While the Programme faces challenges common to most intergovernmental organizations, its achievements in expanding international law and building bioethics capacity should not be underestimated.

  13. THE FINANCING OF THE ACTIVITIES WITHIN THE SECTORIAL OPERATIONAL PROGRAMME “INCREASE OF ECONOMIC COMPETITIVENESS”

    OpenAIRE

    Vasile POPEANGĂ

    2009-01-01

    The Sectorial Operational Programme “Increase of Economic Competitiveness” (further referred to as SOP IEC) is one of the seven instruments (OPs), under the Convergence objective, for achieving the priorities of the National Strategic Reference Framework (NSRF) derived from the National Development Plan 2007 – 2013 (NDP), which aims to strengthen the strategic focus of the Economic and Social Cohesion policies across Romania, and to make the correct and appropriate ...

  14. Efficiency of the home parental programme in visual-motor home activity among first-grade children.

    Science.gov (United States)

    Ratzon, N Z; Zabaneh-Tannas, K; Ben-Hamo, L; Bart, Orit

    2010-03-01

    The objectives of this study were to assess the efficacy of the home parental programme (HPP) in improving children's visual-motor skills, and to assess parent satisfaction with the programme. Forty-five children and their parents participated in the study: 23 children and their parents in the study group (children receiving consultation in the classroom and whose parents participated in the HPP) and 22 children and their parents in the control group (children receiving consultation in the classroom only). All children were recruited based on their scores on the Visual Motor Integration test or upon teacher referral. The Developmental Test of Visual Perception-2 administered before and after intervention served as an outcome measure. HPP lasted approximately 12 weeks and included relevant visual-motor activities carried out at home by the parents with their children. The study failed to prove that HPP improved children's visual-motor skills beyond the other service delivery methods used in the present study. Parent satisfaction was significantly higher among those who participated in the HPP. Parents showed high compliance with the friendly programme despite their low socio-economic status.

  15. REVIEW OF THE NATIONAL RESTOCKING PROGRAMMEACTIVE PROTECTION OF NATIVE CRAYFISH IN POLAND” 1999-2001

    Directory of Open Access Journals (Sweden)

    ŠMIETANA P.

    2004-01-01

    Full Text Available After the first spread of crayfish plague (aphanomycosis at the end of the nineteenth century, the formerly abundant populations of native crayfish in Poland declined drastically. Analysis of historical data on the occurrence and distribution of crayfish in Poland led to the conclusion that without human intervention the native crayfish species would be at high risk of being made extinct. The largest programme concerning crayfish monitoring and restocking in Poland was “Active protection of native crayfish in Poland” conducted by the Inland Fisheries Institute, the Department of Ecology, University of Szczecin, the Department of Zoology, Warsaw Agricultural University and the University of Warmia and Mazury that was funded by the EkoFundusz Foundation and Inland Fisheries Institute in 1999-2001. One of the main objectives and results of this programme was the determination of indigenous crayfish distribution in Poland (mainly Astacus astacus and Astacus leptodactylus and the restocking of suitable habitats with indigenous crayfish. The densest populations (> 2 500 adult individuals per hectare were used as a source of restocking material. Restocking was performed in 54 water bodies using a total of 45 200 individuals of A. astacus and 9 800 of A. leptodactylus. Between 2001-2002, the success of the restocking programme was monitored. According to the results obtained so far, the restocking exercise has been successful in at least 60.8% of the cases.

  16. Have guidelines addressing physical activity been established in nonalcoholic fatty liver disease?

    Institute of Scientific and Technical Information of China (English)

    Carmine Finelli; Giovanni Tarantino

    2012-01-01

    The purpose of this review was to highlight,in relation to the currently accepted pathophysiology of non-alcoholic fatty liver disease (NAFLD),the known exercise habits of patients with NAFLD and to detail the benefits of lifestyle modification with exercise (and/or physical activity) on parameters of metabolic syndrome.More rigorous,controlled studies of longer duration and defined histopathological end-points comparing exercise alone and other treatment are needed before better,evidence-based physical activity modification guidelines can be established,since several questions remain unanswered.

  17. Finnish bioenergy research programme

    Energy Technology Data Exchange (ETDEWEB)

    Asplund, D. [VTT Energy, Jyvaeskylae (Finland)

    1996-12-31

    Finland is a leading country in the use of biofuels and has excellent opportunities to increase the use of biofuels by up to 25-30 %. The Finnish Government has set an objective for the promotion of bioenergy. The aim is to increase the use of bioenergy by about 25 % from the present level by 2005, and the increment corresponds to 1.5 million tonnes of oil equivalent (toe) per year. The R and D work has been considered as an important factor to achieve this ambitious goal. Energy research was organised into a series of research programmes in 1988 in accordance with the proposal of Finnish Energy Research Committee. The object of the research programmes is to enhance research activities and to bundle individual projects together into larger research packages. The common target of the Finnish energy research programmes is to proceed from basic and applied research to product development and pilot operation, and after that to the first commercial applications, e.g. demonstrations. As the organisation of energy research to programmes has led to good results, the Finnish Ministry of Trade and Industry decided to go on with this practice by launching new six-year programmes in 1993-1998. One of these programmes is the Bioenergy Research Programme and the co-ordination of this programme is carried out by VTT Energy. Besides VTT Energy the Finnish Forest Research Institute, Work Efficiency Institute, Metsaeteho and University of Joensuu are participating in the programme 7 refs.

  18. A cluster-randomised controlled trial of a physical activity and nutrition programme in retirement villages: a study protocol.

    Science.gov (United States)

    Holt, Anne-Marie; Jancey, Jonine; Lee, Andy H; Kerr, Deborah A; Hills, Andrew P; Anderson, Annie S; Howat, Peter A

    2014-09-25

    Physical activity levels of Australia's ageing population are declining and coincidentally rates of overweight and obesity are increasing. Adequate levels of physical activity and a healthy diet are recognised as important lifestyle factors for the maintenance of a healthy weight and prevention of chronic diseases. Retirement village (RV) residents rarely engage in physical activity and nutrition programmes offered, with poor attendance and low use of existing facilities such as on-site fitness centres and classes and nutrition seminars. The RV provides a unique setting to access and engage with this older target group, to test the effectiveness of strategies to increase levels of physical activity, improve nutrition and maintain a healthy weight. This cluster-randomised controlled trial will evaluate a physical activity, nutrition and healthy weight management intervention for insufficiently active ('not achieving 150 min of moderate-intensity physical activity per week') adults aged 60-75 residing in RV's. A total of 400 participants will be recruited from 20 randomly selected RV's in Perth, Western Australia. Villages will be assigned to either the intervention group (n=10) or the control group (n=10) each containing 200 participants. The Retirement Village Physical Activity and Nutrition for Seniors (RVPANS) programme is a home-based physical activity and nutrition programme that includes educational resources, along with facilitators who will motivate and guide the participants during the 6-month intervention. Descriptive statistics and mixed regression models will be performed to assess the intervention effects. This trial will evaluate an intervention for the modification of health risk factors in the RV setting. Such research conducted in RV's has been limited. Curtin University Human Research Ethics Committee (approval number: HR128/2012). Dissemination of the study results will occur through publications, reports, conference presentations and community

  19. The special programme of research in human reproduction: forty years of activities to achieve reproductive health for all.

    Science.gov (United States)

    Benagiano, Giuseppe; d'Arcangues, Catherine; Harris Requejo, Jennifer; Schafer, Alessandra; Say, Lale; Merialdi, Mario

    2012-01-01

    The Special Programme of Research in Human Reproduction (HRP), co-sponsored by the UNDP, UNFPA, WHO, and the World Bank, is celebrating 40 years of activities with an expansion of its mandate and new co-sponsors. When it began, in 1972, the main focus was on evaluating the acceptability, effectiveness, and safety of existing fertility-regulating methods, as well as developing new, improved modalities for family planning. In 1994, HRP not only made major contributions to the Plan of Action of the International Conference on Population and Development (ICPD); it also broadened its scope of work to include other aspects of health dealing with sexuality and reproduction, adding a specific perspective on gender issues and human rights. In 2002, HRP's mandate was once again broadened to include sexually transmitted infections and HIV/AIDS and in 2003 it was further expanded to research activities on preventing violence against women and its many dire health consequences. Today, the work of the Programme includes research on: the sexual and reproductive health of adolescents, women, and men; maternal and perinatal health; reproductive tract and sexually transmitted infections (including HIV/AIDS); family planning; infertility; unsafe abortion; sexual health; screening for cancer of the cervix in developing countries, and gender and reproductive rights. Additional activities by the Programme have included: fostering international cooperation in the field of human reproduction; the elaboration of WHO's first Global Reproductive Health Strategy; work leading to the inclusion of ICPD's goal 'reproductive health for all by 2015' into the Millennium Development Goal framework; the promotion of critical interagency statements on the public health, legal, and human rights implications of female genital mutilation and gender-biased sex selection. Finally, HRP has been involved in the creation of guidelines and tools, such as the 'Medical eligibility criteria for contraceptive use

  20. Research programme 'Active Solar Energy Use - Solar Heating and Heat Storage'. Activities and projects 2003; Programme 'Solaire actif - Chaleur et Stockage de chaleur'. Activites et projets en 2003

    Energy Technology Data Exchange (ETDEWEB)

    Hadorn, J.-C. [Base Consultants, Geneva (Switzerland); Renaud, P. [Planair SA, La Sagne (Switzerland)

    2003-07-01

    In this report by the research, development and demonstration (RD+D) programme coordinators the objectives, activities and main results in the area of solar heating and heat storage in Switzerland are presented for 2003. In a stagnating market environment the strategy of the Swiss Federal Office of Energy mainly consists in improving the quality and durability of solar collectors and materials, optimizing combisystems for space heating and domestic hot water preparation, searching for storage systems with a higher energy storage density than in the case of sensible heat storage in water, developing coloured solar collectors for more architectonic freedom, and finalizing a seasonal heat storage project for 100 dwellings to demonstrate the feasibility of solar fractions larger than 50% in apartment houses. Support was granted to the Swiss Testing Facility SPF in Rapperswil as in previous years; SPF was the first European testing institute to perform solar collector labeling according to the new rules of the 'Solar Keymark', introduced in cooperation with the European Committee for Standardization CEN. Several 2003 projects were conducted within the framework of the Solar Heating and Cooling Programme of the International Energy Agency IEA. Computerized simulation tools were improved. With the aim of jointly producing high-temperature heat and electric power a solar installation including a concentrating collector and a thermodynamic machine based on a Rankine cycle is still being developed. Seasonal underground heat storage was studied in detail by means of a validated computer simulation programme. Design guidelines were obtained for such a storage used in the summer time for cooling and in the winter time for space heating via a heat pump: depending on the ratio 'summer cooling / winter heating', cooling requires a cooling machine, or direct cooling without such a machine is possible. The report ends up with the list of all supported RD

  1. A switch from low to high Shh activity regulates establishment of limb progenitors and signaling centers.

    Science.gov (United States)

    Zhulyn, Olena; Li, Danyi; Deimling, Steven; Vakili, Niki Alizadeh; Mo, Rong; Puviindran, Vijitha; Chen, Miao-Hsueh; Chuang, Pao-Tien; Hopyan, Sevan; Hui, Chi-chung

    2014-04-28

    The patterning and growth of the embryonic vertebrate limb is dependent on Sonic hedgehog (Shh), a morphogen that regulates the activity of Gli transcription factors. However, Shh expression is not observed during the first 12 hr of limb development. During this phase, the limb bud is prepatterned into anterior and posterior regions through the antagonistic actions of transcription factors Gli3 and Hand2. We demonstrate that precocious activation of Shh signaling during this early phase interferes with the Gli3-dependent specification of anterior progenitors, disturbing establishment of signaling centers and normal outgrowth of the limb. Our findings illustrate that limb development requires a sweet spot in the level and timing of pathway activation that allows for the Shh-dependent expansion of posterior progenitors without interfering with early prepatterning functions of Gli3/Gli3R or specification of anterior progenitors.

  2. Establishing a faith-based organisation nursing school within a national primary health care programme in rural Tanzania: an auto-ethnographic case study

    Directory of Open Access Journals (Sweden)

    Alexander Bischoff

    2016-05-01

    Full Text Available Background: In 2007, the Tanzanian government called for improvements in its primary health care services. Part of this initiative was to accelerate the training rate for nurses qualified to work in rural areas. The aim of this study was to reflect on the issues experienced whilst establishing and implementing a faith-based organisation (FBO nursing school and make recommendations for other similar initiatives. Design: This paper describes an auto-ethnographic case study design to identify the key difficulties involved with establishing and implementing a new nursing school, and which factors helped the project achieve its goals. Results: Six themes emerged from the experiences that shaped the course of the project: 1 Motivation can be sustained if the rationale of the project is in line with its aims. Indeed, the project's primary health care focus was to strengthen the nursing workforce and build a public–private partnership with an FBO. All these were strengths, which helped in the midst of all the uncertainties. 2 Communication was an important and often underrated factor for all types of development projects. 3 Managing the unknown and 4 managing expectations characterised the project inception. Almost all themes had to do with 5 handling conflicts. With so many participants having their own agendas, tensions were unavoidable. A final theme was 6 the need to adjust to ever-changing targets. Conclusions: This retrospective auto-ethnographic manuscript serves as a small-scale case study, to illustrate how issues that can be generalised to other settings can be deconstructed to demonstrate how they influence health development projects in developing countries. From this narrative of experiences, key recommendations include the following: 1 Find the right ratio of stakeholders, participants, and agendas, and do not overload the project; 2 Be alert and communicate as much as possible with staff and do not ignore issues hoping they will solve

  3. Evaluation of Antibiotics Active against Methicillin-Resistant Staphylococcus aureus Based on Activity in an Established Biofilm.

    Science.gov (United States)

    Meeker, Daniel G; Beenken, Karen E; Mills, Weston B; Loughran, Allister J; Spencer, Horace J; Lynn, William B; Smeltzer, Mark S

    2016-10-01

    We used in vitro and in vivo models of catheter-associated biofilm formation to compare the relative activity of antibiotics effective against methicillin-resistant Staphylococcus aureus (MRSA) in the specific context of an established biofilm. The results demonstrated that, under in vitro conditions, daptomycin and ceftaroline exhibited comparable activity relative to each other and greater activity than vancomycin, telavancin, oritavancin, dalbavancin, or tigecycline. This was true when assessed using established biofilms formed by the USA300 methicillin-resistant strain LAC and the USA200 methicillin-sensitive strain UAMS-1. Oxacillin exhibited greater activity against UAMS-1 than LAC, as would be expected, since LAC is an MRSA strain. However, the activity of oxacillin was less than that of daptomycin and ceftaroline even against UAMS-1. Among the lipoglycopeptides, telavancin exhibited the greatest overall activity. Specifically, telavancin exhibited greater activity than oritavancin or dalbavancin when tested against biofilms formed by LAC and was the only lipoglycopeptide capable of reducing the number of viable bacteria below the limit of detection. With biofilms formed by UAMS-1, telavancin and dalbavancin exhibited comparable activity relative to each other and greater activity than oritavancin. Importantly, ceftaroline was the only antibiotic that exhibited greater activity than vancomycin when tested in vivo in a murine model of catheter-associated biofilm formation. These results emphasize the need to consider antibiotics other than vancomycin, most notably, ceftaroline, for the treatment of biofilm-associated S. aureus infections, including by the matrix-based antibiotic delivery methods often employed for local antibiotic delivery in the treatment of these infections.

  4. Efficacy of a compulsory homework programme for increasing physical activity and healthy eating in children: the healthy homework pilot study

    Directory of Open Access Journals (Sweden)

    Duncan Scott

    2011-11-01

    Full Text Available Abstract Background Most physical activity and nutrition interventions in children focus on the school setting; however, evidence suggests that children are less active and have greater access to unhealthy food at home. The aim of this pilot study was to examine the efficacy of a compulsory homework programme for increasing physical activity and healthy eating in children. Methods The six-week 'Healthy Homework' programme and complementary teaching resource was developed under the guidance of an intersectoral steering group. Eight senior classes (year levels 5-6 from two diverse Auckland primary schools were randomly assigned into intervention and control groups. A total of 97 children (57 intervention, 40 control aged 9-11 years participated in the evaluation of the intervention. Daily step counts were monitored immediately before and after the intervention using sealed multiday memory pedometers. Screen time, sports participation, active transport to and from school, and the consumption of fruits, vegetables, unhealthy foods and drinks were recorded concurrently in a 4-day food and activity diary. Results Healthy Homework resulted in a significant intervention effect of 2,830 steps.day-1 (95% CI: 560, 5,300, P = 0.013. This effect was consistent between sexes, schools, and day types (weekdays and weekend days. In addition, significant intervention effects were observed for vegetable consumption (0.83 servings.day-1, 95% CI: 0.24, 1.43, P = 0.007 and unhealthy food consumption (-0.56 servings.day-1, 95% CI: -1.05, -0.07, P = 0.027 on weekends but not weekdays, with no interactions with sex or school. Effects for all other variables were not statistically significant regardless of day type. Conclusions Compulsory health-related homework appears to be an effective approach for increasing physical activity and improving vegetable and unhealthy food consumption in children. Further research in a larger study is required to confirm these initial

  5. The ACIGA data analysis programme

    Energy Technology Data Exchange (ETDEWEB)

    Scott, Susan M; Searle, Antony C; Cusack, Benedict J; McClelland, David E [Department of Physics, Faculty of Science, Australian National University, Canberra ACT 0200 (Australia)

    2004-03-07

    The data analysis programme of the Australian Consortium for Interferometric Gravitational Astronomy (ACIGA) was set up in 1998 by Scott to complement the then existing ACIGA programmes working on suspension systems, lasers and optics and detector configurations. The ACIGA data analysis programme continues to contribute significantly in the field; we present an overview of our activities.

  6. The ACIGA Data Analysis programme

    CERN Document Server

    Scott, S M; Cusack, B J; McClelland, D E; Scott, Susan M; Searle, Antony C; Cusack, Benedict J; Clelland, David E Mc

    2004-01-01

    The Data Analysis programme of the Australian Consortium for Interferometric Gravitational Astronomy (ACIGA) was set up in 1998 by the first author to complement the then existing ACIGA programmes working on suspension systems, lasers and optics, and detector configurations. The ACIGA Data Analysis programme continues to contribute significantly in the field; we present an overview of our activities.

  7. Assessing the importance of human activities for the establishment of the invasive Poa annua in Antarctica

    Directory of Open Access Journals (Sweden)

    Marco A. Molina-Montenegro

    2014-06-01

    Full Text Available Because of its harsh environmental conditions and remoteness, Antarctica is often considered to be at low risk of plant invasion. However, an increasing number of reports have shown the presence and spread of non-native plants in Antarctica; it is therefore important to study which factors control the invasion process in this ecosystem. Here, we assessed the role of different human activities on the presence and abundance of the invasive Poa annua. In addition, we performed a reciprocal transplant experiment in the field, and a manipulative experiment of germination with P. annua and the natives Colobanthus quitensis and Deschampsia antarctica, in order to unravel the effects of physical soil disturbance on the establishment and survival of P. annua. We found a positive correlation between abundance of P. annua and level of soil disturbance, and that survival of P. annua was 33% higher in sites with disturbed soil than non-disturbed. Finally, we found that disturbance conditions increased germination for P. annua, whereas for native species germination in experimentally disturbed soil was either unchanged or reduced compared to undisturbed soil. Our results indicate that human activities that modify abiotic soil characteristics could play an important role in the abundance of this invasive species. If the current patterns of human activities are maintained in Antarctica, the establishment success and spread of P. annua could increase, negatively affecting native flora.

  8. Genome-scale definition of the transcriptional programme associated with compromised PU.1 activity in acute myeloid leukaemia.

    Science.gov (United States)

    Sive, J I; Basilico, S; Hannah, R; Kinston, S J; Calero-Nieto, F J; Göttgens, B

    2016-01-01

    Transcriptional dysregulation is associated with haematological malignancy. Although mutations of the key haematopoietic transcription factor PU.1 are rare in human acute myeloid leukaemia (AML), they are common in murine models of radiation-induced AML, and PU.1 downregulation and/or dysfunction has been described in human AML patients carrying the fusion oncogenes RUNX1-ETO and PML-RARA. To study the transcriptional programmes associated with compromised PU.1 activity, we adapted a Pu.1-mutated murine AML cell line with an inducible wild-type PU.1. PU.1 induction caused transition from leukaemia phenotype to monocytic differentiation. Global binding maps for PU.1, CEBPA and the histone mark H3K27Ac with and without PU.1 induction showed that mutant PU.1 retains DNA-binding ability, but the induction of wild-type protein dramatically increases both the number and the height of PU.1-binding peaks. Correlating chromatin immunoprecipitation (ChIP) Seq with gene expression data, we found that PU.1 recruitment coupled with increased histone acetylation induces gene expression and activates a monocyte/macrophage transcriptional programme. PU.1 induction also caused the reorganisation of a subgroup of CEBPA binding peaks. Finally, we show that the PU.1 target gene set defined in our model allows the stratification of primary human AML samples, shedding light on both known and novel AML subtypes that may be driven by PU.1 dysfunction.

  9. Konaklama İşletmelerinde İşe Alıştırma Eğitiminin Örgütsel Bağlılığa Etkisi(The Effect of Orientation Programme on Organisational Commitment in Hospitality Establishments

    Directory of Open Access Journals (Sweden)

    Edip ÖRÜCÜ

    2014-06-01

    Full Text Available Organisational commitment is one of the most important variable to determine of emplyee’s behavior. Morover organisational commitment is a major predictor of employees behaviors such as e,g. turnover intention, job loyalty, job performance and motivation. On the other hand orientation rogramme is a crucial process to develop an uniform organisational culture. Orientation programme has inversely relationship with turnover behaviour. For this reason the purpose of this study is to examine relationships between orientation and organisational commitment. In six hotel establishments where is in Balıkesir was examined a questionarrrie to determinate the effect of orientation programme on organisational commitment and the benefits of orientation programme on 53 hotel employees. According to the result of analysis it was exposed that content of orientation programme and benefits of orientation programme has highly lineer correlation.

  10. Establishing the Impact of Model Surfactants on Cloud Condensation Nuclei Activation of Sea Spray Aerosols

    Science.gov (United States)

    Forestieri, S.; Cappa, C. D.; Ruehl, C. R.

    2016-12-01

    Aerosol impacts on cloud properties, also known as indirect effects, remain a major source of uncertainty in modeling global radiative forcing. To reduce this uncertainty necessitates better understanding of how aerosol chemical composition impacts the cloud-forming ability of aerosols. It is well established that both size and hygroscopicity impact the cloud condensation nuclei (CCN) activity of aerosols. Previous studies demonstrate that the presence of surface-active organic material in aerosols can also reduce the surface tension of activating droplets, thereby enhancing CCN activity. We quantified surface tension of microscopic droplets using a continuous-flow stream-wise thermal gradient chamber at humidities close to activation for multi-component lab-generated sea spray aerosol (SSA) proxies. The SSA proxies used were atomized NaCl or synthetic sea salt coated with one to many various fatty acids found in nascent SSA particles. Observed surface tension values near the point of activation as a function of chemical composition for various SSA proxies will be presented.

  11. Establishment and Activity of the D Quadrant Organizer in the Marine Gastropod Crepidula fornicata.

    Science.gov (United States)

    Henry, Jonathan Q; Lyons, Deirdre C; Perry, Kimberly J; Cornelia Osborne, Chen

    2017-09-05

    During development in metazoan embryos, the fundamental embryonic axes are established by organizing centers that influence the fates of nearby cells. Among the spiralians, a large and diverse branch of protostome metazoans, studies have shown that an organizer sets up the dorsal-ventral axis, which arises from one of the four basic cell quadrants during development (the dorsal, D quadrant). Studies in a few species have also revealed variation in terms of how and when the D quadrant and the organizer are established. In some species the D quadrant is specified conditionally, via cell-cell interactions, while in others it is specified autonomously, via asymmetric cell divisions (such as those involving the formation of polar lobes). The third quartet macromere (3D) typically serves as the spiralian organizer; however, other cells born earlier or later in the D quadrant lineage can serve as the organizer, such as the 2d micromere in the annelid Capitella teleta or the 4d micromere in the mollusc Crepidula fornicata. Here we present work carried out in the snail C. fornicata to show that establishment of a single D quadrant appears to rely on a combination of both autonomous (via inheritance of the polar lobe) and conditional mechanisms (involving induction via the progeny of the first quartet micromeres). Through systematic ablation of cells, we show that D quadrant identity is established between 5th and 6th cleavage stages, as it is in other spiralians that use conditional specification. Subsequently, following the next cell cycle, organizer activity takes place soon after the birth of the 4d micromere. Therefore, unlike the case in other spiralians that use conditional specification, the specification of the D quadrant and the activity of the dorso-ventral organizer are temporally and spatially uncoupled. We also present data on organizer function in naturally-occurring and experimentally-induced twin embryos, which possess multiple D quadrants. We show that

  12. THE FINANCING OF THE ACTIVITIES WITHIN THE SECTORIAL OPERATIONAL PROGRAMME “INCREASE OF ECONOMIC COMPETITIVENESS”

    Directory of Open Access Journals (Sweden)

    Vasile POPEANGĂ

    2009-12-01

    Full Text Available The Sectorial Operational Programme “Increase of Economic Competitiveness” (further referred to as SOP IEC is one of the seven instruments (OPs, under the Convergence objective, for achieving the priorities of the National Strategic Reference Framework (NSRF derived from the National Development Plan 2007 – 2013 (NDP, which aims to strengthen the strategic focus of the Economic and Social Cohesion policies across Romania, and to make the correct and appropriate linkages to the European policies and the Lisbon Strategy for growth and job creation. SOP IEC was elaborated under the coordination of the Managing Authority for SOP IEC -Ministry of Economy and Finance (MEF, and is the result of the partnership consultations both with the strategic partners (ACIS within MEF, other MAs–ministries coordinating other OPs, institutions designated as Intermediate Bodies, other line ministries, and agencies, social partners, civil society organizations, potential beneficiaries, other stakeholders involved in this field.

  13. Assessing the Financial Viability of Academic Programmes

    Science.gov (United States)

    Swift, Lynette

    2012-01-01

    This paper reviews and examines approaches to determining the financial viability of academic programmes as a critical component of assessing a programme's overall sustainability. Key to assessing the financial viability of a programme is understanding the teaching activities required to deliver the programme and the cost of those activities. A…

  14. Fellows, Associates & Students Programmes

    CERN Document Server

    2005-01-01

    The present document reviews the CERN Fellows, Associates and Students Programmes emphasizing the developments since 2000, when the previous review was presented to the Scientific Policy Committee, Finance Committee and Council (CERN/2325), and makes proposals for the coming five years. In summary, it is proposed to â?¢ Simplify the payment scheme for the Paid Scientific Associates Programme, which will no longer depend on candidateâ??s home support and age; â?¢ Broaden the scope of the Fellowship Programme, in order to facilitate the recruitment of young graduates in computing and engineering. Age-related eligibility conditions and payment levels will be replaced with experience-based criteria; â?¢ Modify subsistence rates for the Doctoral and Technical Student Programme in order to harmonize CERNâ??s payment levels with those offered by other research establishments. This document is presented for discussion and recommendation by the Scientific Policy Committee and approval by the Council. Additiona...

  15. Acceptance test of an activity meter to be used as reference in a calibration methodology establishment

    Energy Technology Data Exchange (ETDEWEB)

    Correa, Eduardo L.; Kuahara, Lilian T.; Potiens, Maria da Penha A., E-mail: educorrea1905@gmail.com [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2014-07-01

    The nuclear medicine is a medical physics area in which radiopharmaceuticals are used in diagnostic procedures. These radioactive elements are administered in the patient and the radiation emitted is detected by an equipment, that makes the body scan, connected to a computer software, and the image is constructed. In order to operate the nuclear medicine service must have calibrated radiation detectors. Thought, it does not exist, in Brazil, an activity meter calibration methodology, which causes many measurement uncertainties. The goal of this study is to present the acceptance test results of an activity meter to be used as reference in a new calibration methodology establishment. It was checked an activity meter Capintec, CRC-25R model, using three control sources ({sup 137}Cs, {sup 57}Co, {sup 133}Ba). The tests were based on the CNEN-NN 3.05 standard, the manufacturer manual, the TRS-454 and the TECDOC 602 and include: physical inspection, chamber voltage, zero adjustment, background response, data check and repeatability. The linearity and geometry tests could not be made, because the laboratory where the activity meter is located is not authorized to receive non-sealed radioactive sources. The equipment has presented a good behavior. All the results are in the range presented by national and international standards and the equipment is now being used in the laboratory and periodically passes through the quality control tests. (author)

  16. Localized serine protease activity and the establishment of Drosophila embryonic dorsoventral polarity.

    Science.gov (United States)

    Stein, David; Cho, Yong Suk; Stevens, Leslie M

    2013-01-01

    Drosophila embryo dorsoventral polarity is established by a maternally encoded signal transduction pathway in which three sequentially acting serine proteases, Gastrulation Defective, Snake and Easter, generate the ligand that activates the Toll receptor on the ventral side of the embryo. The spatial regulation of this pathway depends upon ventrally restricted expression of the Pipe sulfotransferase in the ovarian follicle during egg formation. Several recent observations have advanced our understanding of the mechanism regulating the spatially restricted activation of Toll. First, several protein components of the vitelline membrane layer of the eggshell have been determined to be targets of Pipe-mediated sulfation. Second, the processing of Easter by Snake has been identified as the first Pipe-dependent, ventrally-restricted processing event in the pathway. Finally, Gastrulation Defective has been shown to undergo Pipe-dependent, ventral localization within the perivitelline space and to facilitate Snake-mediated processing of Easter. Together, these observations suggest that Gastrulation Defective, localized on the interior ventral surface of the eggshell in association with Pipe-sulfated eggshell proteins, recruits and mediates an interaction between Snake and Easter. This event leads to ventrally-restricted processing and activation of Easter and consequently, localized formation of the Toll ligand, and Toll activation.

  17. REHABILITATION PRACTICAL PROGRAMME

    Directory of Open Access Journals (Sweden)

    Suzana KRANJC JOLDIKJ

    Full Text Available Centre for Education and Rehabilitation of Physi­cally Handicapped Children and Adolescents Kamnik (Zavod za usposabljanje invalidne mlad­ine Kamnik; hereinafter: ZUIM perform verified or state-ap­proved programme the Rehabilitation practical pro­gramme. The programme is intended for all those young people, who have completed primary school education, but cannot continue regular schooling in secondary school pro­grammes. The programme con­sists of several equivalent parts: education, practical work, train­ing work, health, therapeutic, psychologi­cal, and other activities. For every beginner in the first month of education members of the operative team create an individualized programme, which in­cludes individualized school work, individualized training programme, and other expert activities. The programme can last for 6 years maximum, it can however be completed earlier, when the op­erative team feels the training is no longer neces­sary. Pro­gress of a young person is what matters the most, and if there is no progress, the training is brought to an end. Training of young people in the Rehabilitation practical programme is only the be­ginning. The country will have to start considering social enter­prises, which are found elsewhere in the world, for example in Scandinavian countries and in the USA.

  18. A structured physical activity and fitness programme for older adults with intellectual disabilities : Results of a cluster-randomised clinical trial

    NARCIS (Netherlands)

    van Schijndel-Speet, M.; Evenhuis, Heleen M.; van Wijck, R.; van Montfort, K. C. A. G. M.; Echteld, M. A.

    BackgroundThe physical activity level of older adults with intellectual disabilities (ID) is extremely low, and their fitness levels are far beneath accepted norms for older people with normal intelligence and comparable with frail older people. A physical activity programme, including an education

  19. Establishment of Epithelial Attachment on Titanium Surface Coated with Platelet Activating Peptide

    Science.gov (United States)

    Sugawara, Shiho; Maeno, Masahiko; Lee, Cliff; Nagai, Shigemi; Kim, David M.; Da Silva, John; Kondo, Hisatomo

    2016-01-01

    The aim of this study was to produce epithelial attachment on a typical implant abutment surface of smooth titanium. A challenging complication that hinders the success of dental implants is peri-implantitis. A common cause of peri-implantitis may results from the lack of epithelial sealing at the peri-implant collar. Histologically, epithelial sealing is recognized as the attachment of the basement membrane (BM). BM-attachment is promoted by activated platelet aggregates at surgical wound sites. On the other hand, platelets did not aggregate on smooth titanium, the surface typical of the implant abutment. We then hypothesized that epithelial BM-attachment was produced when titanium surface was modified to allow platelet aggregation. Titanium surfaces were coated with a protease activated receptor 4-activating peptide (PAR4-AP). PAR4-AP coating yielded rapid aggregation of platelets on the titanium surface. Platelet aggregates released robust amount of epithelial chemoattractants (IGF-I, TGF-β) and growth factors (EGF, VEGF) on the titanium surface. Human gingival epithelial cells, when they were co-cultured on the platelet aggregates, successfully attached to the PAR4-AP coated titanium surface with spread laminin5 positive BM and consecutive staining of the epithelial tight junction component ZO1, indicating the formation of complete epithelial sheet. These in-vitro results indicate the establishment of epithelial BM-attachment to the titanium surface. PMID:27741287

  20. Inhibition of establishment of primary and micrometastatic tumors by a urokinase plasminogen activator receptor antagonist.

    Science.gov (United States)

    Ignar, D M; Andrews, J L; Witherspoon, S M; Leray, J D; Clay, W C; Kilpatrick, K; Onori, J; Kost, T; Emerson, D L

    1998-01-01

    Tumor establishment and metastasis are dependent on extracellular matrix proteolysis, tumor cell migration, and angiogenesis. Urokinase plasminogen activator (uPA) and its receptor are essential mediators of these processes. The purpose of this study was to investigate the effect of a recombinant human uPAR antagonist on growth, establishment, and metastasis of tumors derived from human cancer cell lines. A noncatalytic recombinant protein, consisting of amino acids 1-137 of human uPA and the CH2 and CH3 regions of mouse IgG1 (uPA-IgG), was expressed, purified, and shown to bind specifically to human uPAR and to saturate the surface of human tumor cells which express uPAR. Daily i.p. administration of uPA-IgG to nude mice extended latencies of unstaged tumors derived from Lox melanoma and SW48 colon carcinoma cells by 7.7 and 5.5 days, respectively. uPA-IgG treatment did not affect the growth of Lox or KB tumors staged to 200 mg before antagonist treatment commenced. The effect of uPA-IgG on the establishment of micrometastases was assessed in SCID mice. KB head/neck tumor cells were injected in the tail vein and allowed to seed for 48 h before initiation of daily i.p. injections of uPA-IgG for 24 days. The number of lung colonies ranged between 5 and 30% of vehicle-treated mice in two separate experiments. Furthermore, a single 800 microg dose of uPA-IgG administered 1 h prior to tail vein injection of KB cells reduced lung colony formation to just 3.5% of vehicle-treated SCID mice. These data demonstrate that antagonism of uPAR arrested metastasis and inhibited the establishment of primary tumors and micrometastases. Thus, small molecule uPAR antagonists may serve as useful adjuvant agents in combination with existing cancer chemotherapy.

  1. The I.A.G. / A.I.G. SEDIBUD (Sediment Budgets in Cold Environments) Programme: Current and future activities

    Science.gov (United States)

    Beylich, Achim A.; Lamoureux, Scott; Decaulne, Armelle

    2013-04-01

    Projected climate change in cold regions is expected to alter melt season duration and intensity, along with the number of extreme rainfall events, total annual precipitation and the balance between snowfall and rainfall. Similarly, changes to the thermal balance are expected to reduce the extent of permafrost and seasonal ground frost and increase active layer depths. These effects will undoubtedly change surface environments in cold regions and alter the fluxes of sediments, nutrients and solutes, but the absence of quantitative data and coordinated geomorphic process monitoring and analysis to understand the sensitivity of the Earth surface environment is acute in cold climate environments. The International Association of Geomorphologists (I.A.G. / A.I.G. ) SEDIBUD (Sediment Budgets in Cold Environments) Programme was formed in 2005 to address this existing key knowledge gap. SEDIBUD currently has about 400 members worldwide and the Steering Committee of this international programme is composed of ten scientists from eight different countries: Achim A. Beylich (Chair) (Norway), Armelle Decaulne (Secretary) (France), John C. Dixon (USA), Scott F. Lamoureux (Vice-Chair) (Canada), John F. Orwin (Canada), Jan-Christoph Otto (Austria), Irina Overeem (USA), Thorsteinn Sæmundsson (Iceland), Jeff Warburton (UK) and Zbigniew Zwolinski (Poland). The central research question of this global group of scientists is to: Assess and model the contemporary sedimentary fluxes in cold climates, with emphasis on both particulate and dissolved components. Initially formed as European Science Foundation (ESF) Network SEDIFLUX (Sedimentary Source-to-Sink Fluxes in Cold Environments) (2004 - ), SEDIBUD has further expanded to a global group of researchers with field research sites located in polar and alpine regions in the northern and southern hemisphere. Research carried out at each of the close to 50 defined SEDIBUD key test sites varies by programme, logistics and available

  2. SWOV programme 2003-2006.

    NARCIS (Netherlands)

    2012-01-01

    SWOV uses a four-year programme to structure its activities over a longer period of time. The current four-year programme, for 2003-2006, includes proposals for so-called planning office activities, anticipatory research, knowledge management, and knowledge dissemination. The research activities are

  3. An novel analog programmable power supply for active gain control of the Multi-Pixel Photon Counter (MPPC)

    CERN Document Server

    Li, Zhengwei; Xu, Yupeng; Yan, Bo; Li, Yanguo; Lu, Xuefeng; Li, Xufang; Zhang, Shuo; Chang, Zhi; Li, Jicheng; Zhang, Yifei; Zhao, Jianling

    2016-01-01

    Silicon Photo-Multipliers (SiPM) are regarded as novel photo-detector to replace conventional Photo-Multiplier Tubes (PMTs). However, the breakdown voltage dependence on the ambient temperature results in a gain variation of $\\sim$3$\\% /^{\\circ} \\mathrm C$. This can severely limit the application of this device in experiments with wide range of operating temperature, especially in space telescope. An experimental setup in dark condition was established to investigate the temperature and bias voltage dependence of gain for the Multi-Pixel Photon Counter (MPPC), one type of the SiPM developed by Hamamatsu. The gain and breakdown voltage dependence on operating temperature of an MPPC can be approximated by a linear function, which is similar to the behavior of a zener diode. The measured temperature coefficient of the breakdown voltage is $(59.4 \\pm 0.4$ mV)$/^{\\circ} \\mathrm C$. According to this fact, a programmable power supply based on two zener diodes and an operational amplifier was designed with a positiv...

  4. Origami-inspired active graphene-based paper for programmable instant self-folding walking devices

    OpenAIRE

    Mu, Jiuke; Hou, Chengyi; Wang, Hongzhi; Li, Yaogang; Zhang, Qinghong; Zhu, Meifang

    2015-01-01

    Origami-inspired active graphene-based paper with programmed gradients in vertical and lateral directions is developed to address many of the limitations of polymer active materials including slow response and violent operation methods. Specifically, we used function-designed graphene oxide as nanoscale building blocks to fabricate an all-graphene self-folding paper that has a single-component gradient structure. A functional device composed of this graphene paper can (i) adopt predesigned sh...

  5. Greek Teachers Programme 2015

    CERN Multimedia

    Hoch, Michael

    2015-01-01

    The 3rd edition of this year's Greek Teachers Programme was co-organized by CERN Education Group and the Hellenic Physical Society and took place from 8 to 12 November 2015. The programme targets physics high-school teachers from all over Greece. It aims to help teachers inspire the next generation of scientists and engineers by motivating their students to understand and appreciate how science works at the world's largest physics laboratory, whereby increasing their interest in pursuing studies in STEM fields in secondary and post-secondary education. 33 teachers took part in this programme which comprised lectures by Greek members of the CERN scientific community, with visits to experimental facilities, hands-on activities and dedicated sessions on effective and creative ways through which participants may bring physics, particle physics and CERN closer to their school classroom. In 2015, more than 100 teachers took part in the three editions of the Greek Teachers Programme.

  6. Effect of the Great Activity Programme on healthy lifestyle behaviours in 7-11 year olds.

    Science.gov (United States)

    Morris, John G; Gorely, Trish; Sedgwick, Matthew J; Nevill, Alan; Nevill, Mary E

    2013-01-01

    The study investigated the effect of a school-based healthy lifestyles intervention on physical activity and dietary variables. In total 378 children (177 intervention, 201 control; age 9.75 ± 0.82 years (mean ± s)) took part in the 7-month intervention comprising: preparation for and participation in 3 highlight events (a dance festival, a walking event and a running event); an interactive website for pupils, teachers and parents; and vacation activity planners. Primary outcome measures were objectively measured physical activity (pedometers and accelerometers), endurance fitness and dietary variables. Multi-level modelling was employed for data analysis. The increase in physical activity was greater in the intervention group than the control group (steps: 1049 vs 632 daily steps each month; moderate to vigorous physical activity (MVPA) total: 4.6 min · day(-1) · month(-1) vs 1.3 min · day(-1) · month(-1); MVPA bouts: 5.4 min · day(-1) · month(-1) vs 2.6 min · day(-1) · month(-1); all P fitness test distance was greater for intervention participants (46 vs 29 m · month(-1) of intervention, group × month interaction, P healthy lifestyles or psychological variables. Thus an intervention centred around highlight events and including relatively few additional resources can impact positively on the objectively measured physical activity of children.

  7. European Identity through Space Space Activities and Programmes as a Tool to Reinvigorate the European Identity

    CERN Document Server

    Baranes, Blandina

    2013-01-01

    Space activities are one particularly visible area, where Europe can shape its identity. This publication investigates the effect space activities have already had on building a European “spirit” (e.g. through European missions or European astronauts). It also looks into the effects that activities labelled “national” have on the emergence of a European identity. Based on this analysis, the book's intention is to identify creative ways and means for how to further use space for shaping the European identity. For this purpose the focus is not only on policy analysis but also on expertise from the fields of cultural science and the arts in order to tap their creative potential and also their theoretical approaches to the topic. Selecting this theme provides ESPI with another opportunity to develop its trans-disciplinary approach.

  8. Strategies to improve the implementation of healthy eating, physical activity and obesity prevention policies, practices or programmes within childcare services.

    Science.gov (United States)

    Wolfenden, Luke; Jones, Jannah; Williams, Christopher M; Finch, Meghan; Wyse, Rebecca J; Kingsland, Melanie; Tzelepis, Flora; Wiggers, John; Williams, Amanda J; Seward, Kirsty; Small, Tameka; Welch, Vivian; Booth, Debbie; Yoong, Sze Lin

    2016-10-04

    Despite the existence of effective interventions and best-practice guideline recommendations for childcare services to implement policies, practices and programmes to promote child healthy eating, physical activity and prevent unhealthy weight gain, many services fail to do so. The primary aim of the review was to examine the effectiveness of strategies aimed at improving the implementation of policies, practices or programmes by childcare services that promote child healthy eating, physical activity and/or obesity prevention. The secondary aims of the review were to:1. describe the impact of such strategies on childcare service staff knowledge, skills or attitudes;2. describe the cost or cost-effectiveness of such strategies;3. describe any adverse effects of such strategies on childcare services, service staff or children;4. examine the effect of such strategies on child diet, physical activity or weight status. We searched the following electronic databases on 3 August 2015: the Cochrane Central Register of Controlled trials (CENTRAL), MEDLINE, MEDLINE In Process, EMBASE, PsycINFO, ERIC, CINAHL and SCOPUS. We also searched reference lists of included trials, handsearched two international implementation science journals and searched the World Health Organization International Clinical Trials Registry Platform (www.who.int/ictrp/) and ClinicalTrials.gov (www.clinicaltrials.gov). We included any study (randomised or non-randomised) with a parallel control group that compared any strategy to improve the implementation of a healthy eating, physical activity or obesity prevention policy, practice or programme by staff of centre-based childcare services to no intervention, 'usual' practice or an alternative strategy. The review authors independently screened abstracts and titles, extracted trial data and assessed risk of bias in pairs; we resolved discrepancies via consensus. Heterogeneity across studies precluded pooling of data and undertaking quantitative

  9. Methodological Establishment of HPLC-DAD for Determination of 10 Active Ingredients in Wuweizi

    Directory of Open Access Journals (Sweden)

    Feng YAO

    2015-09-01

    Full Text Available Objective: To establish high performance liquid chromatography-diode array detection (HPLC-DAD method for the determination of active ingredients of multiple lignans in Nanwuweizi (Kadsura longepedunculata and Beiwuweizi (Fructus Schisandrae Chinensis so as to set up the standard for the quality control of Wuweizi (Schisandra chinensis. Methods: Brava BDS C18 column (250 mm×4.6 mm, 5 μm was applied, with detection condition as follows: column temperature: 30℃; mobile phase: water (A-acetonitrile (B; gradient elution: 0.8 mL/min and detection wavelength: 225 nm.Results: Ten ingredients in Beiwuweizi and 5 in Nanwuweizi were completely separately within 75 min. Peak area was in favorable linear relationship with concentration. In addition, the recovery rate was 96.87-103.29% and relative standard deviation (RSD was 0.68-2.09%.Conclusion: HPLC-DAD is simple and reliable with favorable repeatability, so it can be used for the determination of multiple lignans in Wuweizi.

  10. Methodological Establishment of HPLC-DAD for Determination of 10 Active Ingredients in Wuweizi

    Institute of Scientific and Technical Information of China (English)

    YAO Feng; CHEN Da-shuai

    2015-01-01

    Objective: To establish high performance liquid chromatography-diode array detection (HPLC-DAD) method for the determination of active ingredients of multiple lignans in Nanwuweizi (Kadsura longepedunculata) and Beiwuweizi (Fructus Schisandrae Chinensis) so as to set up the standard for the quality control of Wuweizi (Schisandra chinensis). Methods: Brava BDS C18 column (250 mm×4.6 mm, 5 μm) was applied, with detection condition as follows: column temperature: 30℃; mobile phase: water (A)-acetonitrile (B); gradient elution: 0.8 mL/min and detection wavelength: 225 nm. Results: Ten ingredients in Beiwuweizi and 5 in Nanwuweizi were completely separately within 75 min. Peak area was in favorable linear relationship with concentration. In addition, the recovery rate was 96.87%-103.29% and relative standard deviation (RSD) was 0.68%-2.09%. Conclusion: HPLC-DAD is simple and reliable with favorable repeatability, so it can be used for the determination of multiple lignans in Wuweizi.

  11. Active Agents of Health Promotion? The School's Role in Supporting the HPV Vaccination Programme

    Science.gov (United States)

    Spratt, Jennifer; Shucksmith, Janet; Philip, Kate; McNaughton, Rebekah

    2013-01-01

    By providing a place in which children can be accessed, the school has long been a site for population-level health initiatives. Recent policy shifts towards health-promoting schools have however re-cast the school from passive host to active collaborator in public health. This paper examines secondary school teachers' views of their roles as…

  12. Positive Youth Development through an Outdoor Physical Activity Programme: Evidence from a Four-Year Evaluation

    Science.gov (United States)

    Armour, Kathleen; Sandford, Rachel

    2013-01-01

    In 2006, Sandford, Armour and Warmington undertook a comprehensive review of the literature on the role of physical activity/sport and physical education in promoting positive development for disaffected youth. This paper revisits the findings of the literature review in light of data from a four-year evaluation of one corporate-sponsored physical…

  13. Male Adolescents' View on Sexual Activity as Basis for the Development of Aids-Prevention Programmes.

    Science.gov (United States)

    Steyn, Hester; Myburgh, Chris P.H.; Poggenpoel, Marie

    2005-01-01

    The world regards AIDS as the most disastrous health threat in the world. HIV/AIDS- related issues amongst adolescents were initially neglected due to the visible impact of this pandemic on babies and adults. Adolescents' behavior is however regarded as high-risk because of their involvement in sexual activities from a young age. The purpose of…

  14. External Mobility Programme

    CERN Document Server

    HR Department

    2007-01-01

    Every year, a significant number of highly-skilled staff members leave the Organization and offer their talents on the European job market. CERN is launching a programme aiming to help staff members to whom the Organization cannot offer an indefinite contract in the transition towards their next employment. The programme, which is based on the establishment of a number of partnerships with potential employers in the private sector, will run on a voluntary basis. Staff members who have received confirmation that they will not be offered an indefinite contract and who are interested in availing themselves of the opportunities offered by the programme, are invited to enrol by following the procedure described at: https://ert.cern.ch/browse_intranet/wd_pds?p_web_page_id=5841 Applications will be processed in the strictest confidence by the Human Resources Department and eligible profiles will then be made available to partner companies for recruitment purposes. Any subsequent ...

  15. Systematic review on the financial return of worksite health promotion programmes aimed at improving nutrition and/or increasing physical activity

    NARCIS (Netherlands)

    Dongen, J.M. van; Proper, K.I.; Wier, M.F. van; Beek, A.J. van der; Bongers, P.M.; Mechelen, W. van; Tulder, M.W. van

    2011-01-01

    Summary: This systematic review summarizes the current evidence on the financial return of worksite health promotion programmes aimed at improving nutrition and/or increasing physical activity. Data on study characteristics and results were extracted from 18 studies published up to 14 January 2011.

  16. Cost-effectiveness of a long-term Internet-delivered worksite health promotion programme on physical activity and nutrition: A cluster randomized controlled trial

    NARCIS (Netherlands)

    S.J.W. Robroek (Suzan); S. Polinder (Suzanne); F.J. Bredt (Folef); A. Burdorf (Alex)

    2012-01-01

    textabstractThis study aims to evaluate the cost-effectiveness of a long-term workplace health promotion programme on physical activity (PA) and nutrition. In total, 924 participants enrolled in a 2-year cluster randomized controlled trial, with departments (n = 74) within companies (n = 6) as the u

  17. Design of a process evaluation of the implementation of a physical activity and sports stimulation programme in Dutch rehabilitation setting : ReSpAct

    NARCIS (Netherlands)

    Hoekstra, Femke; Alingh, Roelina A.; van der Schans, Cees P.; Hettinga, Florentina J.; Duijf, Marjo; Dekker, Rienk; van der Woude, Lucas H. V.

    2014-01-01

    Background: There is a growing interest to study the transfer of evidence-based information into daily practice. The evidence-based programme Rehabilitation, Sports and Exercise (RSE) that aims to stimulate an active lifestyle during and after a rehabilitation period in people with a disability and/

  18. Origami-inspired active graphene-based paper for programmable instant self-folding walking devices.

    Science.gov (United States)

    Mu, Jiuke; Hou, Chengyi; Wang, Hongzhi; Li, Yaogang; Zhang, Qinghong; Zhu, Meifang

    2015-11-01

    Origami-inspired active graphene-based paper with programmed gradients in vertical and lateral directions is developed to address many of the limitations of polymer active materials including slow response and violent operation methods. Specifically, we used function-designed graphene oxide as nanoscale building blocks to fabricate an all-graphene self-folding paper that has a single-component gradient structure. A functional device composed of this graphene paper can (i) adopt predesigned shapes, (ii) walk, and (iii) turn a corner. These processes can be remote-controlled by gentle light or heating. We believe that this self-folding material holds potential for a wide range of applications such as sensing, artificial muscles, and robotics.

  19. Bio-optofluidics and Bio-photonics: Programmable Phase Optics activities at DTU Fotonik

    DEFF Research Database (Denmark)

    Bañas, Andrew Rafael; Palima, Darwin; Pedersen, Finn

    We present ongoing research and development activities for constructing a compact next generation BioPhotonics Workstation and a Bio-optofluidic Cell Sorter (cell-BOCS) for all-optical micromanipulation platforms utilizing low numerical aperture beam geometries. Unlike conventional high NA optica...... the BioPhotonics Workstation platform more photon efficient by studying the 3D distribution of the counter propagating beams and utilizing the Generalized Phase Contrast (GPC) method for illuminating the applied spatial light modulators.......We present ongoing research and development activities for constructing a compact next generation BioPhotonics Workstation and a Bio-optofluidic Cell Sorter (cell-BOCS) for all-optical micromanipulation platforms utilizing low numerical aperture beam geometries. Unlike conventional high NA optical...

  20. Origami-inspired active graphene-based paper for programmable instant self-folding walking devices

    Science.gov (United States)

    Mu, Jiuke; Hou, Chengyi; Wang, Hongzhi; Li, Yaogang; Zhang, Qinghong; Zhu, Meifang

    2015-01-01

    Origami-inspired active graphene-based paper with programmed gradients in vertical and lateral directions is developed to address many of the limitations of polymer active materials including slow response and violent operation methods. Specifically, we used function-designed graphene oxide as nanoscale building blocks to fabricate an all-graphene self-folding paper that has a single-component gradient structure. A functional device composed of this graphene paper can (i) adopt predesigned shapes, (ii) walk, and (iii) turn a corner. These processes can be remote-controlled by gentle light or heating. We believe that this self-folding material holds potential for a wide range of applications such as sensing, artificial muscles, and robotics. PMID:26601135

  1. Bio-optofluidics and Bio-photonics: Programmable Phase Optics activities at DTU Fotonik

    DEFF Research Database (Denmark)

    Bañas, Andrew Rafael; Palima, Darwin; Pedersen, Finn

    We present ongoing research and development activities for constructing a compact next generation BioPhotonics Workstation and a Bio-optofluidic Cell Sorter (cell-BOCS) for all-optical micromanipulation platforms utilizing low numerical aperture beam geometries. Unlike conventional high NA optical...... tweezers, the BioPhotonics workstation is e.g. capable of long range 3D manipulation. This enables a variety of biological studies such as manipulation of intricate microfabricated assemblies or for automated and parallel optofluidic cell sorting. To further reduce its overhead, we propose ways of making...

  2. Programmable SERS active substrates for chemical and biosensing applications using amorphous/crystalline hybrid silicon nanomaterial

    Science.gov (United States)

    Powell, Jeffery Alexander; Venkatakrishnan, Krishnan; Tan, Bo

    2016-01-01

    We present the creation of a unique nanostructured amorphous/crystalline hybrid silicon material that exhibits surface enhanced Raman scattering (SERS) activity. This nanomaterial is an interconnected network of amorphous/crystalline nanospheroids which form a nanoweb structure; to our knowledge this material has not been previously observed nor has it been applied for use as a SERS sensing material. This material is formed using a femtosecond synthesis technique which facilitates a laser plume ion condensation formation mechanism. By fine-tuning the laser plume temperature and ion interaction mechanisms within the plume, we are able to precisely program the relative proportion of crystalline Si to amorphous Si content in the nanospheroids as well as the size distribution of individual nanospheroids and the size of Raman hotspot nanogaps. With the use of Rhodamine 6G (R6G) and Crystal Violet (CV) chemical dyes, we have been able to observe a maximum enhancement factor of 5.38 × 106 and 3.72 × 106 respectively, for the hybrid nanomaterial compared to a bulk Si wafer substrate. With the creation of a silicon-based nanomaterial capable of SERS detection of analytes, this work demonstrates a redefinition of the role of nanostructured Si from an inactive to SERS active role in nano-Raman sensing applications.

  3. FFUSION research programme 1993-1998. Final report of the Finnish fusion research programme

    Energy Technology Data Exchange (ETDEWEB)

    Karttunen, S.; Heikkinen, J.; Korhonen, R. [VTT Energy, Espoo (Finland)] [and others

    1998-12-31

    This report summarizes the results of the Fusion Energy Research Programme, FFUSION, during the period 1993-1998. After the planning phase the programme started in 1994, and later in March 1995 the FFUSION Programme was integrated into the EU Fusion Programme and the Association Euratom-Tekes was established. Research areas in the FFUSION Programme are (1) fusion physics and plasma engineering, (2) fusion reactor materials and (3) remote handling systems. In all research areas industry is involved. Recently, a project on environmental aspects of fusion and other future energy systems started as a part of the socio-economic research (SERF) in the Euratom Fusion Programme. A crucial component of the FFUSION programme is the close collaboration between VTT Research Institutes, universities and Finnish industry. This collaboration has guaranteed dynamic and versatile research teams, which are large enough to tackle challenging research and development projects. Regarding industrial fusion R and D activities, the major step was the membership of Imatran Voima Oy in the EFET Consortium (European Fusion Engineering and Technology), which further strengthened the position of industry in the engineering design activities of ITER. The number of FFUSION research projects was 66. In addition, there were 32 industrial R and D projects. The total cost of the FFUSION Programme in 1993-1998 amounted to FIM 54 million in research at VTT and universities and an additional FIM 21 million for R and D in Finnish industry. The main part of the funding was provided by Tekes, 36%. Since 1995, yearly Euratom funding has exceeded 25%. The FFUSION research teams have played an active role in the European Programme, receiving excellent recognition from the European partners. Theoretical and computational fusion physics has been at a high scientific level and the group collaborates with the leading experimental laboratories in Europe. Fusion technology is focused on reactor materials, joining

  4. Human amniotic epithelial cell transplantation induces markers of alternative macrophage activation and reduces established hepatic fibrosis.

    Directory of Open Access Journals (Sweden)

    Ursula Manuelpillai

    Full Text Available Chronic hepatic inflammation from multiple etiologies leads to a fibrogenic response that can progress to cirrhosis and liver failure. Transplantation of human amniotic epithelial cells (hAEC from term delivered placenta has been shown to decrease mild to moderate hepatic fibrosis in a murine model. To model advanced human liver disease and assess the efficacy of hAEC therapy, we transplanted hAEC in mice with advanced hepatic fibrosis. Immunocompetent C57BL/6 mice were administered carbon tetrachloride (CCl(4 twice weekly resulting in bridging fibrosis by 12 weeks. hAEC (2 × 10(6 were infused via the tail vein at week 8 or weeks 8 and 10 (single and double dose, respectively. Human cells were detected in mouse liver four weeks after transplantation showing hAEC engraftment. CCl(4 treated mice receiving single or double hAEC doses showed a significant but similar decrease in liver fibrosis area associated with decreased activation of collagen-producing hepatic stellate cells and decreased hepatic protein levels of the pro-fibrogenic cytokine, transforming growth factor-beta1. CCl(4 administration caused hepatic T cell infiltration that decreased significantly following hAEC transplantation. Hepatic macrophages play a crucial role in both fibrogenesis and fibrosis resolution. Mice exposed to CCl(4 demonstrated increased numbers of hepatic macrophages compared to normal mice; the number of macrophages decreased significantly in CCl(4 treated mice given hAEC. These mice had significantly lower hepatic protein levels of the chemokine monocyte chemoattractant protein-1 than mice given CCl(4 alone. Alternatively activated M2 macrophages are associated with fibrosis resolution. CCl(4 treated mice given hAEC showed increased expression of genes associated with M2 macrophages including YM-1, IL-10 and CD206. We provide novel data showing that hAEC transplantation induces a wound healing M2 macrophage phenotype associated with reduction of established

  5. Fenretinide-induced caspase-8 activation and apoptosis in an established model of metastatic neuroblastoma

    Directory of Open Access Journals (Sweden)

    Bénard Jean

    2009-03-01

    Full Text Available Abstract Background Resistance of high-risk metastatic neuroblastoma (HR-NB to high dose chemotherapy (HD-CT raises a major therapeutic challenge in pediatric oncology. Patients are treated by maintenance CT. For some patients, an adjuvant retinoid therapy is proposed, such as the synthetic retinoid fenretinide (4-HPR, an apoptotic inducer. Recent studies demonstrated that NB metastasis process is enhanced by the loss of caspase-8 involved in the Integrin-Mediated Death (IMD process. As the role of caspase-8 appears to be critical in preventing metastasis, we aimed at studying the effect of 4-HPR on caspase-8 expression in metastatic neuroblasts. Methods We used the human IGR-N-91 MYCN-amplified NB experimental model, able to disseminate in vivo from the primary nude mouse tumor xenograft (PTX into myocardium (Myoc and bone marrow (BM of the animal. NB cell lines, i.e., IGR-N-91 and SH-EP, were treated with various doses of Fenretinide (4-HPR, then cytotoxicity was analyzed by MTS proliferation assay, apoptosis by the propidium staining method, gene or protein expressions by RT-PCR and immunoblotting and caspases activity by colorimetric protease assays. Results The IGR-N-91 parental cells do not express detectable caspase-8. However the PTX cells established from the primary tumor in the mouse, are caspase-8 positive. In contrast, metastatic BM and Myoc cells show a clear down-regulation of the caspase-8 expression. In parallel, the caspases -3, -9, -10, Bcl-2, or Bax expressions were unchanged. Our data show that in BM, compared to PTX cells, 4-HPR up-regulates caspase-8 expression that parallels a higher sensitivity to apoptotic cell death. Stable caspase-8-silenced SH-EP cells appear more resistant to 4-HPR-induced cell death compared to control SH-EP cells. Moreover, 4-HPR synergizes with drugs since apoptosis is restored in VP16- or TRAIL-resistant-BM cells. These results demonstrate that 4-HPR in up-regulating caspase-8 expression

  6. Nutritional counselling and its effects on diet, nutritional knowledge and status, physical activity and quality of life in a Southern Europe population: evaluation of a health promotion programme.

    Directory of Open Access Journals (Sweden)

    Cecilia Quercioli

    2011-06-01

    Full Text Available

    Abstract:
    Background: Health promotion and primary prevention are key points for fighting the increase in non- communicable diseases. Aim: To test the effectiveness of a nutritional counselling programme in improving nutritional behaviours, knowledge and status, physical activity and health-related quality of life in a general population. Methods: In the period between January–December 2007, we studied the application of the nutritional counselling programme (NCP developed by Local Health Agency 10 (Florence-Italy. We compared , diet, nutritional knowledge, physical activity, health related quality of life (measured by SF36 questionnaire, body mass index (BMI and waist circumference before and after a two months intensive nutritional counselling programme using the paired t test and McNemar test. Diet, nutritional knowledge, physical activity, socio-demographic and morbidity information were collected through questionnaires. BMI and waist circumference were assessed by a medical doctor. Results: We enrolled 74 persons, 59 of whom completed the educational programme. Of these, 34 had a nutritional status assessment after the programme. Mean age was 49 years, 80% were females. BMI, waist circumference and diet, except for water intake, did not change. The percentage of people who had “never exercised in a week" decreased from 46% to 17% (p<0.001. Mean percentage of right answers to nutritional knowledge indicators increased from 64% to 78% (p<0.001. Health related quality of life (HRQL improved especially with regard to “Physical" and “Emotional Role". Conclusions: The NCP showed important results in promoting physical activity and improving HRQL and nutritional knowledge, moderate/none results in improving diet and nutritional status.

  7. Evaluation of beta spectrometry for environmental monitoring of undeclared nuclear activities. Report on task FIN A846 on the Finnish support programme to IAEA safeguards

    Energy Technology Data Exchange (ETDEWEB)

    Rosenberg, R.; Lipponen, M. [VTT Chemical Technology, Espoo (Finland); Jaakkola, T. [Helsinki Univ. (Finland). Dept. of Radiochemistry

    1996-03-01

    The IAEA (the Agency) is considering environmental monitoring as a possible method to detect the presence of undeclared nuclear activities in a country covered by a comprehensive safeguards agreement. The Finnish support program (FINSP), implemented by the Finnish Centre for Radiation and Nuclear Safety (STUK), is supporting the Agency in this new programme. This Agency Task FIN A 846, addresses the possibility of using beta-emitting nuclides as indicators for covert nuclear fuel reprocessing activities. (90 refs., 1 fig., 12 tabs.).

  8. The SEDIBUD (Sediment Budgets in Cold Environments) Programme: Ongoing activities and selected key tasks for the coming years

    Science.gov (United States)

    Beylich, Achim A.; Lamoureux, Scott F.; Decaulne, Armelle

    2012-09-01

    Projected climate change in cold environments is expected to alter melt-season duration and intensity, along with the number of extreme rainfall events, total annual precipitation and the balance between snowfall and rainfall. In addition, changes to the thermal balance are expected to reduce the extent of permafrost and seasonal ground frost and increase active layer depths. The combined effects of these changes will alter surface environments in cold climate regions and change the fluxes of sediments, nutrients and solutes, but the absence of data, coordinated process monitoring and coordinated quantitative analysis to understand the sensitivity of the Earth surface environment are acute in cold climate environments. The International Association of Geomorphologists (I.A.G./A.I.G.) SEDIBUD (Sediment Budgets in Cold Environments) Programme has been formed to address this key knowledge gap and builds on the earlier European Science Foundation (ESF) SEDIFLUX (Sedimentary Source-to-Sink-Fluxes in Cold Environments) Network. Coordinated efforts are carried out to monitor, quantify, compare and model sedimentary fluxes and possible effects of predicted climate change in currently 44 selected SEDIBUD Key Test Sites (cold climate environment catchments) worldwide.

  9. Recruitment of a mast-fruiting, bird-dispersed tree: Bridging frugivore activity and seedling establishment

    OpenAIRE

    Herrera, Carlos M.; Jordano, Pedro; López-Soria, L.; Amat, Juan A.

    1994-01-01

    The recruitment of Phillyrea latifolia L. (Oleaceae), a bird-dispersed tree of Mediterranean forest, is described. Fruit removal by birds, seed rain, post-dispersal seed predation, seed germination, and seedling emergence, survival, and establishment were studied. The main objective was testing whether seed dispersal by birds produced a predictable seedling shadow as a result of coupled patterns of seed rain, seedling emergence, and seedling establishment. P. latifolia is a mast-fruiting spec...

  10. Activating welfare recipients with health complaints: Reasons for failure of a cognitive training programme

    Directory of Open Access Journals (Sweden)

    Inge Bramsen

    2011-03-01

    Een groeiende nadruk op de activering van uitkeringsgerechtigden heeft in veel Westerse verzorgingsstaten geleid tot de ontwikkeling van interventies die gericht zijn op uitkeringsgerechtigden met gezondheidsklachten. Vormen van dwang, zoals verplichte participatie, worden meer en meer toegepast binnen dit activeringsbeleid. Een voorbeeld hiervan is het Nederlandse project “Gezond aan de Slag”, dat een interventie ontwikkelde en evalueerde waarin een fysiek trainingsprogramma gecombineerd wordt met cognitieve training. Hoewel HtW als “best practice” gold, liet een randomized trial geen positieve effecten van de interventie zien. Omdat het cognitieve trainingsprogramma, gebaseerd op rationeel-emotieve therapie, niet eerder afzonderlijk werd bestudeerd, werd een diepgaande kwalitatieve studie uitgevoerd. Getracht werd om de oorzaken van het falen van het programma in kaart te brengen. Zes, gericht geselecteerde, trainers werden geïnterviewd. De resultaten lieten zien dat de trainers problemen hadden met de heterogeniteit van de deelnemersgroep en op andere problemen, verwachtingen en arbeidsmarktobstakels stuitten dan vooraf verwacht. De verplichte aard van HtW had een negatief effect op de motivatie van zowel deelnemers als trainers. In de discussieparagraaf van dit artikel worden vraagtekens geplaatst bij de veronderstelling dat de coping stijl en cognities van uitkeringsgerechtigden met gezondheidsproblemen de belangrijkste hindernissen zijn voor het vinden van werk, en worden vraagtekens geplaatst bij het beleid om fysieke beperkingen van deelnemers te negeren. De auteurs suggereren dat met betrekking tot dit complexe praktijkprobleem, verbetering kan worden bereikt door aanpassen en leren van de interventie gedurende de toepassing daarvan toe te staan, en door expliciet te reflecteren op de normatieve aspecten van de interventie, en de perspectieven van de uitkeringsgerechtigden zelf.

  11. Cigotica programme: pediatric experiences

    Directory of Open Access Journals (Sweden)

    Lešović Snežana

    2011-01-01

    Full Text Available Introduction The alarming spread of obesity epidemic in children and adolsecents, as well as the absence of tested and efficient measures and programmes on obesity preven­tion indicate the necessity for the establishment of the Centre for the prevention, treatment and rehabilitation of obesity in children and adolescents and the 'Cigotica Programme' at the Special Hospital 'Zlatibor'. The advantage of the 'Cigotica' Programme is the multidisciplinary approach to treating obese children, which implies specific education, dietetic interventions with the reduction in the total daily calorie intake, physical activity, medical, educational and psychological support, change of behavior and lifestyle. Objective To define obesity complications, metabolic risk factors and treatment effects on body composition and metabolic parameters in adolescents participating in the 'Cigotica' Programme. Method 1,030 adolescents were examined (498 girls and 532 boys, aged 12 to 18, average age 15.45, diagnosed with primary obesity, hospitalized at the Centre for the prevention, treatment and rehabilitation of obesity in children and adolescents at the Special Hospital 'Zlatibor', in the period from 27/07/2008 to 03/10/2010. Hospitalization lasted 21 days. Obesity criterion was body mass index (BMI > +2 SD . Body The Special Hospital for the Thyroid Gland and Metabolism Zlatibor mass, BMI, % of fat were obtained by means of Tanita scales for determining body composition using the impendence method. Apart from medical examination, blood pressure was also taken. The levels of triglycerides, total HDL and LDL cholesterols, uric acids and glycemia were determined on the second and twenty-first day of hospitalization after a 12-day fasting period. Results After the multidisciplinary treatment, the average reduction in body mass (p< 0.05 in all adolescents was 5.92 ± 2.71 kg, in boys - 6.24 ±3.24 kg, and in girls -5.86±2.4. During the 21-day hospitalization, the average

  12. VIP in construction: systematic development and evaluation of a multifaceted health programme aiming to improve physical activity levels and dietary patterns among construction workers

    Directory of Open Access Journals (Sweden)

    Viester Laura

    2012-01-01

    Full Text Available Abstract Background The prevalence of both overweight and musculoskeletal disorders (MSD in the construction industry is high. Many interventions in the occupational setting aim at the prevention and reduction of these health problems, but it is still unclear how these programmes should be designed. To determine the effectiveness of interventions on these health outcomes randomised controlled trials (RCTs are needed. The aim of this study is to systematically develop a tailored intervention for prevention and reduction of overweight and MSD among construction workers and to describe the evaluation study regarding its (cost-effectiveness. Methods/Design The Intervention Mapping (IM protocol was applied to develop and implement a tailored programme aimed at the prevention and reduction of overweight and MSD. The (cost- effectiveness of the intervention programme will be evaluated using an RCT. Furthermore, a process evaluation will be conducted. The research population will consist of blue collar workers of a large construction company in the Netherlands. Intervention The intervention programme will be aimed at improving (vigorous physical activity levels and healthy dietary behaviour and will consist of tailored information, face-to-face and telephone counselling, training instruction (a fitness "card" to be used for exercises, and materials designed for the intervention (overview of the company health promoting facilities, waist circumference measuring tape, pedometer, BMI card, calorie guide, recipes, and knowledge test. Main study parameters/endpoints The intervention effect on body weight and waist circumference (primary outcome measures, as well as on lifestyle behaviour, MSD, fitness, CVD risk indicators, and work-related outcomes (i.e. productivity, sick leave (secondary outcome measures will be assessed. Discussion The development of the VIP in construction intervention led to a health programme tailored to the needs of construction

  13. Reducing musculoskeletal injury and concussion risk in schoolboy rugby players with a pre-activity movement control exercise programme: a cluster randomised controlled trial.

    Science.gov (United States)

    Hislop, Michael D; Stokes, Keith A; Williams, Sean; McKay, Carly D; England, Mike E; Kemp, Simon P T; Trewartha, Grant

    2017-08-01

    Injury risk in youth rugby has received much attention, highlighting the importance of establishing evidence-based injury reduction strategies. To determine the efficacy of a movement control exercise programme in reducing injuries in youth rugby players and to investigate the effect of programme dose on injury measures. In a cluster-randomised controlled trial, 40 independent schools (118 teams, 3188 players aged 14-18 years) were allocated to receive either the intervention or a reference programme, both of which were to be delivered by school coaches. The intervention comprised balance training, whole-body resistance training, plyometric training, and controlled rehearsal of landing and cutting manoeuvres. Time-loss (>24 hours) injuries arising from school rugby matches were recorded by coaches and medical staff. 441 time-loss match injuries (intervention, 233; control, 208) were reported across 15 938 match exposure-hours (intervention, 9083; control, 6855). Intention-to-treat results indicated unclear effects of trial arm on overall match injury incidence (rate ratio (RR)=0.85, 90% confidence limits 0.61 to 1.17), although clear reductions were evident in the intervention arm for concussion incidence (RR=0.71, 0.48 to 1.05). When trial arm comparisons were limited to teams who had completed three or more weekly programme sessions on average, clear reductions in overall match injury incidence (RR=0.28, 0.14 to 0.51) and concussion incidence (RR=0.41, 0.17 to 0.99) were noted in the intervention group. A preventive movement control exercise programme can reduce match injury outcomes, including concussion, in schoolboy rugby players when compared with a standardised control exercise programme, although to realise the greatest effects players should complete the programme at least three times per week. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted

  14. Feasibility of an after-school group-based exercise and lifestyle programme to improve cardiorespiratory fitness and health in less-active Pacific and Maori adolescents.

    Science.gov (United States)

    Chansavang, Yongchie; Elley, C Raina; McCaffrey, Brighid; Davidson, Chloe; Dewes, Ofa; Dalleck, Lance

    2015-03-01

    Obesity and low levels of physical activity are increasing among Pacific and Maori adolescents in New Zealand. To assess the feasibility of an after-school exercise and lifestyle programme to improve cardiorespiratory fitness, health and usual activity in less-active Pacific and Maori adolescents over six weeks. Eighteen less-active secondary school students participated. The six-week programme included 3 x 1.5 hour exercise and healthy lifestyle sessions per week. Outcomes included estimated cardiorespiratory fitness (VO2max), insulin resistance (Homeostasis Model Assessment), physical activity, glycated haemoglobin (HbA1c), fasting plasma glucose, blood pressure, waist circumference and fasting lipids, measured at baseline and six weeks. Programme attendance and qualitative comments were also recorded. Student's t-tests were used. Of the 18 students enrolled, 16 (89%) completed six-week follow-up, 14 (78%) were female, 13 (72%) were Pacific ethnicity and 5 (28%) were Maori . At baseline, mean age was 16.3 (standard deviation [SD] 1.0) years, body mass index (BMI) 35.2 (SD 6.7) kg/m2, VO2max 31.5 (SD 4.3) mL/kg/min, systolic blood pressure 125.0 (SD 12.9) mm Hg, HbA1c 39.9 (SD 3.8) mmol/mol, fasting serum insulin 28.3 (SD 27.8) μU/mL. At follow-up, improvements had occurred in VO2max (3.2 mL/kg/min; p=0.02), systolic blood pressure (-10.6 mm Hg; p=0.003), HbA1c (-1.1 mmol/mol; p=0.03) and weekly vigorous (4 hours, p=0.002) and moderate (2 hours, p=0.006) physical activity, although waist circumference increased (p=0.005). Programme attendance was over 50%. Comments were mostly positive. The after-school exercise and lifestyle programme and study methods were feasible. Such programmes have the potential to improve health outcomes for Pacific and Maori adolescents.

  15. Establishment and evaluation of a multi-system chain transitional care programme for postpartum pelvic floor training%产后盆底功能训练的延续护理模式构建及效果评价

    Institute of Scientific and Technical Information of China (English)

    霍然; 王惠珍; 石兰萍; 张巍颖; 吴震云; 陈学丽

    2014-01-01

    Objective To build a multi-system chain transitional care programme for postpartum pelvic floor training and test its effect.Methods By a prospective randomized controlled trial,the study group (n=60) received a multi-system chain transitional care programme which consisted of ward nurse,home visiting doctor,post-natal care clinic doctor,pelvic floor doctor and pelvic floor nurse.The control group(n=60) received routine care.The pelvic floor muscle strength,sexual function and patient satisfaction of baseline,on the 42th days,3rd months and 6th months were compared between two groups by short-term follow-up.Results There was no difference in baseline consisting of age,gestational weeks,birth weight and so on between groups.Participants in the study group had significantly better improvement and score in pelvic floor muscle strength,sexual thoughts,sexual arousal,sexual psychopathy and problems affecting sexual function.There was no difference in score of sexual pleasure and ejaculation time between two groups.Conclusions This study was an original effort to establish and evaluate a multi-system chain transitional care program for postpartum pelvic floor training.Results demonstrated that this transitional care was effective in improving pelvic floor function.%目的 构建产后盆底功能训练的延续护理模式并检验其效果.方法 采用前瞻性随机对照实验,延续护理60例接受病房责任护士-家庭访视医生-产后保健门诊医生-盆底诊疗中心医生-盆底诊疗中心护士构成的延续护理服务,对照组60例接受传统护理服务.随访和比较2组的基线情况,42 d、3个月和6个月盆底肌肌力、性功能和患者满意度.结果 2组在年龄、孕周、新生儿体质量等基线情况上比较差异无统计学意义.延续护理组在盆底肌肌力改善、性欲、性唤起、性心理和性行为异常症状上得分,以及患者满意度均优于对照组,差异有统计学意义.2组在性高潮和性

  16. SET-Routes programme

    CERN Multimedia

    Marietta Schupp, EMBL Photolab

    2008-01-01

    Dr Sabine Hentze, specialist in human genetics, giving an Insight Lecture entitled "Human Genetics – Diagnostics, Indications and Ethical Issues" on 23 September 2008 at EMBL Heidelberg. Activities in a achool in Budapest during a visit of Angela Bekesi, Ambassadors for the SET-Routes programme.

  17. Using intervention mapping to develop a culturally appropriate intervention to prevent childhood obesity: the HAPPY (Healthy and Active Parenting Programme for Early Years) study.

    Science.gov (United States)

    Taylor, Natalie J; Sahota, Pinki; Sargent, Judith; Barber, Sally; Loach, Jackie; Louch, Gemma; Wright, John

    2013-12-28

    Interventions that make extensive use of theory tend to have larger effects on behaviour. The Intervention Mapping (IM) framework incorporates theory into intervention design, implementation and evaluation, and was applied to the development of a community-based childhood obesity prevention intervention for a multi-ethnic population. IM was applied as follows: 1) Needs assessment of the community and culture; consideration of evidence-base, policy and practice; 2) Identification of desired outcomes and change objectives following identification of barriers to behaviour change mapped alongside psychological determinants (e.g. knowledge, self-efficacy, intention); 3) Selection of theory-based methods and practical applications to address barriers to behaviour change (e.g., strategies for responsive feeding); 4) Design of the intervention by developing evidence-based interactive activities and resources (e.g., visual aids to show babies stomach size). The activities were integrated into an existing parenting programme; 5) Adoption and implementation: parenting practitioners were trained by healthcare professionals to deliver the programme within Children Centres. HAPPY (Healthy and Active Parenting Programme for Early Years) is aimed at overweight and obese pregnant women (BMI > 25); consists of 12 × 2.5 hr. sessions (6 ante-natal from 24 weeks; 6 postnatal up to 9 months); it addresses mother's diet and physical activity, breast or bottle feeding, infant diet and parental feeding practices, and infant physical activity. We have demonstrated that IM is a feasible and helpful method for providing an evidence based and theoretical structure to a complex health behaviour change intervention. The next stage will be to assess the impact of the intervention on behaviour change and clinical factors associated with childhood obesity. The HAPPY programme is currently being tested as part of a randomised controlled feasibility trial.

  18. An economic evaluation of a self-management programme of activity, coping and education for patients with chronic obstructive pulmonary disease.

    Science.gov (United States)

    Dritsaki, Melina; Johnson-Warrington, Vicki; Mitchell, Katy; Singh, Sally; Rees, Karen

    2016-02-01

    The aim was to undertake a cost-utility analysis of a self-management programme of activity, coping and education (SPACE) for chronic obstructive pulmonary disease (COPD). The analysis was conducted alongside a six-month randomized controlled trial in 30 primary care settings. The economic analysis used data from 184 patients with confirmed diagnosis of COPD, forced expiratory volume in one second/forced vital capacity ratio management programme consisting of an education manual (SPACE for COPD) and consultation or usual care. Six-month costs were estimated from the National Health Service and Personal Social Services perspective and quality-adjusted life years (QALYs) were calculated based on patient responses at baseline and six months.The mean difference in costs between usual care and SPACE FOR COPD programme was -£27.18 (95% confidence interval (CI); -£122.59 to £68.25) while mean difference in QALYs was -0.10 (95% CI; -0.17 to -0.02). The results suggest that the intervention is more costly and more effective than usual care. The probability of the intervention being cost-effective was 97% at a threshold of £20,000/QALY gained. We conclude that the SPACE FOR COPD programme is cost-effective compared to usual care.

  19. Breast and cervical cancer screening programme implementation in 16 countries

    DEFF Research Database (Denmark)

    Dowling, Emily C; Klabunde, Carrie; Patnick, Julietta;

    2010-01-01

    There is a continuing need to monitor and evaluate the impact of organized screening programmes on cancer incidence and mortality. We report results from a programme assessment conducted within the International Cancer Screening Network (ICSN) to understand the characteristics of cervical screening...... programmes within countries that have established population-based breast cancer screening programmes....

  20. Effects of 6-month soccer and traditional physical activity programmes on body composition, cardiometabolic risk factors, inflammatory, oxidative stress markers and cardiorespiratory fitness in obese boys.

    Science.gov (United States)

    Seabra, André; Katzmarzyk, Peter; Carvalho, Maria José; Seabra, Ana; Coelho-E-Silva, Manuel; Abreu, Sandra; Vale, Susana; Póvoas, Susana; Nascimento, Henrique; Belo, Luís; Torres, Sandra; Oliveira, José; Mota, Jorge; Santos-Silva, Alice; Rêgo, Carla; Malina, Robert M

    2016-10-01

    Physical activity is important in obesity prevention, but the effectiveness of different physical activity modalities remains to be determined among children. The main purpose of this study was to compare the effects of a 6-month soccer programme and a traditional physical activity programme on changes in body composition, cardiometabolic risk factors, inflammatory and oxidative markers, cardiorespiratory fitness and perceived psychological status in obese boys. Eighty-eight boys (8-12 years; BMI > +2 standard deviations of WHO reference values) participated in one of three groups: soccer, traditional activity and control. Soccer and traditional activity programmes involved 3 sessions per week for 60-90 min at an average intensity of 70-80% of maximal heart rate. Control group participated in activities of normal daily living. All boys participated in school physical education, two sessions per week of 45-90-min. Measurements were taken at baseline and after 6 months, and included body size and composition, cardiometabolic risk factors, inflammatory and oxidative markers, cardiorespiratory fitness and perceived psychological status. Physical activity and dietary intake were assessed before and immediately following the intervention. The three groups had similar characteristics at baseline. After 6 months, both intervention groups had significantly lower relative fatness (% fat), waist circumference and total cholesterol, and higher cardiorespiratory fitness, self-esteem, perceived physical competence and attraction to physical activity compared with control group. In conclusion, physical activity interventions over 6 months positively influenced several indicators of health status among obese boys. The results also suggested that soccer has the potential as an effective tool for the prevention and reduction of childhood obesity and associated consequences.

  1. Developing activities to win the excellence in depth and establishing harmonious relationship between medical care providers and patients

    Directory of Open Access Journals (Sweden)

    Ya-bin JIANG

    2014-08-01

    Full Text Available Further developing activities of striving to be advanced and creating excellence are the need of strengthening party organization of basic level and establishing harmonious society of the socialism. In this paper, we explore the concrete methods of carrying out activities of striving to be advanced and creating excellence in emergency department, and their effects on improving relationship between medical care providers and patients, it has certain theoretical and real significance.

  2. Feasibility and acceptability of a midwife-led intervention programme called 'Eat Well Keep Active' to encourage a healthy lifestyle in pregnancy

    Directory of Open Access Journals (Sweden)

    Warren Lucie

    2012-04-01

    Full Text Available Abstract Background Eating a diet that is high in fat and sugar and having a sedentary lifestyle during pregnancy is understood to increase the risk of excessive gestational weight gain and obesity following the birth of the baby. However, there are no clinical guidelines in the UK on what is considered to be appropriate gestational weight gain. Indeed, clinical recommendations discourage the routine re-weighing of pregnant women, stating instead that women should be advised regarding their diet and activity levels, in order to prevent excessive weight gain. Pregnancy is seen as a time when many women may have an increased motivation to improve their lifestyle behaviours for the benefit of the fetus. However, it is evident that many women have difficulty in both maintaining a healthy balanced diet and remaining active through pregnancy. It would seem that midwives may be ideally placed to assist women to make and maintain healthier lifestyle choices during pregnancy. Methods/design This study will look at the feasibility and acceptability of a newly devised intervention programme called 'Eat Well Keep Active'. Participants will complete a questionnaire prior to the programme to obtain baseline data on food frequency, physical activity and to gauge their perception of personal ability to improve/maintain healthy lifestyle. The programme comprises client centred techniques; motivational interviewing and goal setting delivered early in pregnancy (12-16 weeks with the aim of supporting a healthy well balanced diet and either continuing or commencing appropriate levels of physical activity. Participants will then be followed up six weeks following the intervention with a one-to-one interview, and a further brief questionnaire. The interview will provide preliminary data regarding perceived effectiveness and acceptability of the 'Eat Well Keep Active' programme whilst the questionnaire will provide data regarding changes in the confidence of

  3. Development and implementation of a lifestyle intervention to promote physical activity and healthy diet in the Dutch general practice setting: the BeweegKuur programme

    Directory of Open Access Journals (Sweden)

    de Vries Nanne K

    2010-05-01

    Full Text Available Abstract Background The number of patients with diabetes is increasing. BeweegKuur (Dutch for 'Exercise Therapy' is a Dutch lifestyle intervention which aims to effectively and feasibly promote physical activity and better dietary behaviour in primary health care to prevent diabetes. Methods The goal of this paper is to present the development process and the contents of the intervention, using a model of systematic health promotion planning. The intervention consists of a 1-year programme for diabetic and prediabetic patients. Patients are referred by their general practitioner (GP to a lifestyle advisor (LSA, usually the practice nurse or a physiotherapist. Based on specific inclusion criteria and in close collaboration with the patient, an individual exercise programme is designed and supervised by the LSA. This programme can be attended at existing local exercise facilities or (temporarily under the supervision of a specialized exercise coach or physiotherapist. All participants are also referred to a dietician and receive diet-related group education. In the first pilot year (2008, the BeweegKuur programme was implemented in 7 regions in the Netherlands (19 GP practices and health centres, while 14 regions (41 GP practices and health centres participated during the second year. The aim is to implement BeweegKuur in all regions of the Netherlands by 2012. Discussion The BeweegKuur programme was systematically developed in an evidence- and practice-based process. Formative monitoring studies and (controlled effectiveness studies are needed to examine the diffusion process and the effectiveness and cost-effectiveness of the intervention.

  4. IDIOPATHIC THORACO SCOLIOSIS TREATMENT USING A COMBINATION OF DOCUMENTATION BASED CARE (DBC BACK ACTIVE RECONDITIONING PROGRAMME AND SCHROTH METHODS: A PROSPECTIVE CASE STUDY

    Directory of Open Access Journals (Sweden)

    Ganesan Kathiresan

    2013-10-01

    Full Text Available reconditioning programme and Schroth methods to lessen the curvature allied with idiopathic Thoracicscoliosis.ResearchDesign: Sampling-An 18 years old female, single case study,Setting-DBC Kuching Active rehabilitationcentre, Malaysia.Duration of the study-20 weeks,Outcome measures-A base line and follow-up outcomemeasures includes Borg pain scale, Functional Rating Index, Balance test, and Radiographic analysis.Interventions-Document Based Care (DBC Back active reconditioning programme and Schroth methodsConclusion-The combination of the Document Based Care (DBC Back active reconditioning programme andSchroth methods seemed to be effective at reducing a Thoracic dextroscoliosis by about 14° (50% andLumbarLevoscoliosis by about 7° (25%, Short form (SF-36 showed improvement inQuality of life,balance time on theBalance board improved to 52 seconds and Borg pain scale rated 8/10 at the onset of care, dropped to a 1/10after 20 weeks, in this single case study. The positive outcomes of this practice validate a policyof offeringconservative treatment as an alternative to Thoracic scoliosis patients, including those for whom surgery isdiscussed

  5. Teaching in English-medium programmes

    DEFF Research Database (Denmark)

    Lauridsen, Karen M.; Cozart, Stacey Marie

    on the foundation module in the whole course, this particular module has been established especially for those Danish assistant professors who are to teach in the EMI programmes. The intended learning outcomes are that, at the end of the course, participants should be able to plan and deliver their teaching...... in such a way that they take into account their students’ diverse cultural and linguistic backgrounds and use them as a strength in the classroom; and they should be able to engage all students in joint learning activities so that both the Danish and the international students benefit from the programme....... The overarching idea is thus to develop participants’ awareness of how they can teach for diversity, taking into consideration interlinked cultural, linguistic and didactic issues in the international classroom. The content of the module is closely linked to the assistant professors’ own teaching practice...

  6. Neutron radiography in Indian space programme

    CERN Document Server

    Viswanathan, K

    1999-01-01

    Pyrotechnic devices are indispensable in any space programme to perform such critical operations as ignition, stage separation, solar panel deployment, etc. The nature of design and configuration of different types of pyrotechnic devices, and the type of materials that are put in their construction make the inspection of them with thermal neutrons more favourable than any other non destructive testing methods. Although many types of neutron sources are available for use, generally the radiographic quality/exposure duration and cost of source run in opposite directions even after four decades of research and development. But in the area of space activity, by suitably combining the X-ray and neutron radiographic requirements, the inspection of the components can be made economically viable. This is demonstrated in the Indian space programme by establishing a 15 MeV linear accelerator based neutron generator facility to inspect medium to giant solid propellant boosters by X-ray inspection and all types of critic...

  7. Establishment of national emission measurement activity in neighbouring areas of Finland

    Energy Technology Data Exchange (ETDEWEB)

    Aunela, L.; Larjava, K.; Jormanainen, P. [VTT Chemical Technology, Espoo (Finland). Environmental Technology; Muurinen, M. [Enemi Ltd, Lahti (Finland); Hietamaeki, M. [Ministry of the Environment, Helsinki (Finland)

    1995-12-31

    Estonia, Latvia, and Lithuania (the Baltic countries) and the Republic State of Carelia, Russia belong to the so-called nearby areas of Finland. All being part of the former Soviet Union, they are now undergoing the establishment of their own environment- managing systems. Finland has shown a great amount of interest in supporting the efforts of these areas to solve their environmental problems. In 1993 VTT started, at the request of the East European Project of the Finnish Ministry of the Environment, a four year project aiming at the establishment of national atmospheric emission measurement systems in the Baltic countries and the Republic state of Carelia (later: the counterpart countries). Proper national emission measurement systems were regarded important in order to provide reliable data on the emission situation for national and international use. The main target of the work is to raise the level of the emission measurements in the counterpart countries to the international level. Two aspects were considered to be required to achieve this goal; (1) delivery of proper emission measurement equipment, (2) training of the emission measurement personnel. It was estimated that within three to four years these counterpart countries could join the Finnish quality assurance system in emission measurements if desired. (author)

  8. HIV Latency Is Established Directly and Early in Both Resting and Activated Primary CD4 T Cells.

    Directory of Open Access Journals (Sweden)

    Leonard Chavez

    2015-06-01

    Full Text Available Highly active antiretroviral therapy (HAART suppresses human immunodeficiency virus (HIV replication to undetectable levels but cannot fully eradicate the virus because a small reservoir of CD4+ T cells remains latently infected. Since HIV efficiently infects only activated CD4+ T cells and since latent HIV primarily resides in resting CD4+ T cells, it is generally assumed that latency is established when a productively infected cell recycles to a resting state, trapping the virus in a latent state. In this study, we use a dual reporter virus--HIV Duo-Fluo I, which identifies latently infected cells immediately after infection--to investigate how T cell activation affects the establishment of HIV latency. We show that HIV latency can arise from the direct infection of both resting and activated CD4+ T cells. Importantly, returning productively infected cells to a resting state is not associated with a significant silencing of the integrated HIV. We further show that resting CD4+ T cells from human lymphoid tissue (tonsil, spleen show increased latency after infection when compared to peripheral blood. Our findings raise significant questions regarding the most commonly accepted model for the establishment of latent HIV and suggest that infection of both resting and activated primary CD4+ T cells produce latency.

  9. Auditing emergency management programmes: Measuring leading indicators of programme performance.

    Science.gov (United States)

    Tomsic, Heather

    Emergency Management Programmes benefit from review and measurement against established criteria. By measuring current vs required programme elements for their actual currency, completeness and effectiveness, the resulting timely reports of achievements and documentation of identified gaps can effectively be used to rationally support prioritised improvement. Audits, with their detailed, triangulated and objectively weighted processes, are the ultimate approach in terms of programme content measurement. Although Emergency Management is often presented as a wholly separate operational mechanism, distinct and functionally different from the organisation's usual management structure, this characterisation is only completely accurate while managing an emergency itself. Otherwise, an organisation's Emergency Management Programme is embedded within that organisation and dependent upon it. Therefore, the organisation's culture and structure of management, accountability and measurement must be engaged for the programme to exist, much less improve. A wise and successful Emergency Management Coordinator does not let the separate and distinct nature of managing an emergency obscure their realisation of the need for an organisation to understand and manage all of the other programme components as part of its regular business practices. This includes its measurement. Not all organisations are sufficiently large or capable of supporting the use of an audit. This paper proposes that alternate, less formal, yet effective mechanisms can be explored, as long as they reflect and support organisational management norms, including a process of relatively informal measurement focused on the organisation's own perception of key Emergency Management Programme performance indicators.

  10. ESTABLISHMENT OF THE ANTIOXIDANT/ANTIRADICAL ACTIVITY OF THE INHIBITORS USING THE DPPH–RADICAL

    Directory of Open Access Journals (Sweden)

    Maria Gonta

    2008-06-01

    Full Text Available This research paper presents the results of the investigation of antioxidant activities of various inhibitors, which are constituents of winery products: quercitin, rezveratrol, dihydroxyfumaric acid. Also, the antioxidant activity of tartaric and dihydroxyfumaric (DFH4 acids derivatives has been determined: sodium dihydroxyfumarate, dimethylic ester of DFH4 and dimethylic ester of tartaric acid. The enotannin extracts obtained from grape seeds have been evaluated: the non-oxidized enotannin extract Eneox and the oxidized one -Enoxil.

  11. Data for action: the use of formative research to design a school-based intervention programme to increase physical activity in adolescents.

    Science.gov (United States)

    Murillo Pardo, Berta; Camacho-Miñano, Maria José; Generelo Lanaspa, Eduardo; Julián Clemente, José Antonio; Novais, Carina; Maia Santos, Maria Paula

    2015-09-01

    Formative research is a critical step for the development of interventions aimed at changing behaviours, as is the case of physical activity. This process permits obtaining detailed information about the programme application context. 'Follow the Footstep' is a quasi-experimental and longitudinal study in secondary schools, the aim of which is to increase levels of physical activity among adolescents. To inform the design of the intervention programme, formative research has been carried out to analyse the perceptions of parents, teachers and students, through six focus groups.The social-ecological model was used both to carry out the formative research and then to design the programme, including five levels of influence on behaviour (individual, interpersonal, organizational, community and political), which are important when it comes to adopting a comprehensive intervention approach. The authors describe how the results of formative research were transferred to guide the design and development of the intervention. As results indicate, parents, teachers and students agreed on a need to intervene by engaging adolescents and their close social environment. The school centre is the key organizational structure to implement this intervention, supported by professionals and the community.

  12. Personal goals, group performance and ‘social’ networks: participants’ negotiation of virtual and embodied relationships in the ‘Workplace Challenge’ physical activity programme

    DEFF Research Database (Denmark)

    Evans, Adam Brian; Carter, Alice; Middleton, Geoff

    2016-01-01

    County Sports Partnerships (CSPs) epitomise the growing reliance upon building networks and partnerships in sports delivery. This study investigated how social networks were created and contested in a CSP-led programme entitled the ‘Workplace Challenge’ (WPC). The WPC used a web-platform to encou......County Sports Partnerships (CSPs) epitomise the growing reliance upon building networks and partnerships in sports delivery. This study investigated how social networks were created and contested in a CSP-led programme entitled the ‘Workplace Challenge’ (WPC). The WPC used a web...... in professional I–We identities, whereas virtual networks sometimes highlighted participants’ isolation. Moreover, emphasis upon competition within and between teams caused some participants to question their performance. Often, competition motivated engagement. For less active participants, constant comparison...

  13. A theory evaluation of an induction programme

    Directory of Open Access Journals (Sweden)

    Kenrick Hendricks

    2012-07-01

    Full Text Available Orientation: An induction programme is commonly used to help new employees understand their job within the organisation. Research purpose: The main aim of this study was to examine whether or not the programme theory of an induction programme was plausible and would lead to the intended outcomes as described by the programme manager.Motivation for the study: Induction training is one of the most common training programmes in an organisation. However, there is little research to evaluate whether or not the activities of an induction programme will lead to the intended outcomes of such a programme.Research design, approach and method: This theory evaluation used a descriptive design. One hundred and thirteen employees of a media company completed a ten-item, five-point Likert scale which measured their perceptions of the programme’s outcome, identification with the organisation and intentions to stay with the organisation.Main findings: From this theory evaluation it was apparent that an induction programme based on an implausible programme theory could be problematic. An implausible programme theory affects the design of the programme activities and unsuitable activities may not deliver the desired outcomes.Practical/managerial implications: The intention of the evaluation is to guide human resource managers through a process of replacing an implausible programme theory with one that is plausible, and which ensures better alignment of programme activities and outcomes.Contribution/value-add: The evaluators showed how a plausible programme theory could improve programme design. This redesigned induction programme may lead to benefits, such as staff retention and company identification, rather than the vague assumption that it has been conforming to a legal obligation.

  14. The effects of a home-based arm ergometry exercise programme on physical fitness, fatigue and activity in polio survivors: protocol for a randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Murray Deirdre

    2012-12-01

    Full Text Available Abstract Background Many Polio survivors have reduced mobility, pain and fatigue, which make access to conventional forms of aerobic exercise difficult. Inactivity leads to increased risk of health problems, many of which are prevalent among Polio survivors. Aerobic exercise programmes in Polio survivors should utilise stable muscle groups and should be designed to minimise exacerbation of pain and fatigue. A home-based arm ergometry aerobic exercise programme may represent an affordable and accessible exercise modality, incorporating exercise prescription principles in this group. Methods/design This is a prospective, single blinded, randomised controlled trial. There are two arms; exercise intervention using arm ergometers and control. Polio survivors meeting eligibility criteria will be recruited and randomly allocated to intervention or control groups. Participants allocated to the intervention group will receive a small arm ergometer and a polar heart rate monitor. They will carry out a home-based moderate intensity (50-70% HRMax aerobic exercise programme for eight weeks, following instruction by the treating physiotherapist. Assessments will occur at baseline and after eight weeks and will include tests of physical fitness, activity, energy cost of walking, fatigue and quality of life. Clinically feasible assessment tools including the Six Minute Arm Test, the Physical Activity Scale for People with Physical Disabilities questionnaire, the Physiological Cost Index, Fatigue Severity Scale and the SF-36v2 will be utilised. Discussion The efficacy of a home-based arm ergometry programme in Polio survivors will be examined. No previous trial has examined such a programme using a wide range of outcome measures pertinent to Polio survivors. This study will provide new information on the impact of arm ergometry on physical fitness, activity, body composition, fatigue, pain, muscle strength, and health related quality of life. Also, the study

  15. A switch from low to high Shh activity regulates establishment of limb progenitors and signaling centers

    Science.gov (United States)

    The patterning and growth of the embryonic vertebrate limb is dependent on Sonic hedgehog (Shh), a morphogen that regulates the activity of Gli transcription factors. However, "Shh" expression is not observed during the first 12 hours of limb development. During this phase, the limb bud is prepatter...

  16. Establishing bounding internal dose estimates for thorium activities at Rocky Flats.

    Science.gov (United States)

    Ulsh, Brant A; Rich, Bryce L; Chew, Melton H; Morris, Robert L; Sharfi, Mutty; Rolfes, Mark R

    2008-07-01

    As part of an evaluation of a Special Exposure Cohort petition filed on behalf of workers at the Rocky Flats Plant, the National Institute for Occupational Safety and Health (NIOSH) was required to demonstrate that bounding values could be established for radiation doses due to the potential intake of all radionuclides present at the facility. The main radioactive elements of interest at Rocky Flats were plutonium and uranium, but much smaller quantities of several other elements, including thorium, were occasionally handled at the site. Bounding potential doses from thorium has proven challenging at other sites due to the early historical difficulty in detecting this element through urinalysis methods and the relatively high internal dose delivered per unit intake. This paper reports the results of NIOSH's investigation of the uses of thorium at Rocky Flats and provides bounding dose reconstructions for these operations. During this investigation, NIOSH reviewed unclassified reports, unclassified extracts of classified materials, material balance and inventory ledgers, monthly progress reports from various groups, and health physics field logbooks, and conducted interviews with former Rocky Flats workers. Thorium operations included: (1) an experimental metal forming project with 240 kg of thorium in 1960; (2) the use of pre-formed parts in weapons mockups; (3) the removal of Th from U; (4) numerous analytical procedures involving trace quantities of thorium; and (5) the possible experimental use of thorium as a mold coating compound. The thorium handling operations at Rocky Flats were limited in scope, well-monitored and documented, and potential doses can be bounded.

  17. Established liked versus disliked brands: Brain activity, implicit associations and explicit responses

    Directory of Open Access Journals (Sweden)

    Shannon S. Bosshard

    2016-12-01

    Full Text Available Consumers’ attitudes towards established brands were tested using implicit and explicit measures. In particular, late positive potential (LPP effects were assessed as an implicit neurophysiological measure of motivational significance. The Implicit Association Test (IAT was used as an implicit behavioural measure of valence-related aspects (affective content of brand attitude. We constructed individualised stimulus lists of liked and disliked brand types from participants’ subjective pre-assessment. Participants then re-rated these visually presented brands whilst brain potential changes were recorded via electroencephalography (EEG. First, self-report measures during the test confirmed pre-assessed attitudes underlining consistent explicit rating performance. Second, liked brands elicited significantly more positive going waveforms (LPPs than disliked brands over right parietal cortical areas starting at about 800 ms post stimulus onset (reaching statistical significance at around 1,000 ms and lasting until the end of the recording epoch (2,000 ms. In accordance to the literature, this finding is interpreted as reflecting positive affect-related motivational aspects of liked brands. Finally, the IAT revealed that both liked and disliked brands indeed are associated with affect-related valence. The increased levels of motivation associated with liked brands is interpreted as potentially reflecting increased purchasing intention, but this is of course only speculation at this stage.

  18. Establishing a definition of polar bear (Ursus maritimus) health: A guide to research and management activities

    Science.gov (United States)

    Patyk, Kelly A.; Duncan, Colleen G.; Nol, Pauline; Sonne, C.; Laidre, Kristin L.; Obbard, Martyn E.; Wiig, Øystein; Aars, Jon; Regehr, Eric V.; Gustafson, L.; Atwood, Todd C.

    2015-01-01

    The meaning of health for wildlife and perspectives on how to assess and measure health, are not well characterized. For wildlife at risk, such as some polar bear (Ursus maritimus) subpopulations, establishing comprehensive monitoring programs that include health status is an emerging need. Environmental changes, especially loss of sea ice habitat, have raised concern about polar bear health. Effective and consistent monitoring of polar bear health requires an unambiguous definition of health. We used the Delphi method of soliciting and interpreting expert knowledge to propose a working definition of polar bear health and to identify current concerns regarding health, challenges in measuring health, and important metrics for monitoring health. The expert opinion elicited through the exercise agreed that polar bear health is defined by characteristics and knowledge at the individual, population, and ecosystem level. The most important threats identified were in decreasing order: climate change, increased nutritional stress, chronic physiological stress, harvest management, increased exposure to contaminants, increased frequency of human interaction, diseases and parasites, and increased exposure to competitors. Fifteen metrics were identified to monitor polar bear health. Of these, indicators of body condition, disease and parasite exposure, contaminant exposure, and reproductive success were ranked as most important. We suggest that a cumulative effects approach to research and monitoring will improve the ability to assess the biological, ecological, and social determinants of polar bear health and provide measurable objectives for conservation goals and priorities and to evaluate progress.

  19. ISOLDE PROGRAMME

    CERN Multimedia

    Fedosseev, V; Lynch, K M; Grob, L K; Herfurth, F; Scheidenberger, C; Geppert, C; Gorges, C; Ratajczyk, T; Vogel, S; Munch, M K; Nieminen, P; Pakarinen, J J A; Lecesne, N; Bouzomita, H; Grinyer, J; Marques moreno, F M; Parlog, M; Pedroza, J; Ghetta, V; Lozeva, R; Guillemaud mueller, D S; Cottereau, E; Cheikh mhamed, M; Tusseau nenez, S; Tungate, G; Walker, P M; Smith, A G; Fitzpatrick, C; Dominik, W M; Karny, M; Ciemny, A A; Nyman, G H; Thies, R M A; Lindberg, S K G; Langouche, G F; Delaure, B J P; Mayet, P; Ory, G T; Kesteloot, N J K; Papuga, J; Dehairs, M H R; Callens, M; Boudreau, M; Domnanich, K A; Richter, D; Lutter, R J; Wiehr, S; Nacher gonzalez, E; Jungclaus, A; Ribeiro jimenez, G; Marroquin alonso, I; Cal gonzalez, J; Paziy, V; Salsac, M; Murphy, C; Podolyak, Z F; Bajoga, A D; Butler, P; Pritchard, A; Steer, A N; Fox, S P; Wadsworth, B A; Truesdale, V L; Al monthery, M; Guttormsen, M S; Ingeberg, V W; Badea, M N; Calinescu, S; Cederkall, J A; Zemlyanoy, S; Donets, E D; Golovkov, M; Wu, C; Harrichunder, S; Ncube, M; Gerten, R F; Lehnert, J; Gladnishki, K A; Rainovski, G I; Pospisil, S; Datta pramanik, U; Benzoni, G; Fedorov, D; Molkanov, P; Pfeiffer, B; Griesel, T; Wehner, L W; Mikkelsen, M; Recchia, F; Smith, J F; Kelly, C M; De melo bandeira tavares, P M; Vieira, J M; Martins da silva, M A; Lima lopes, A M; Mader, J; Kessler, P; Laurent, B G; Schweikhard, L C; Marx, G H; Kulczycka, E; Komorowska, M; Da silva, M F; Goncalves marques, C P; Baptista peres, M A; Welander, J E; Leimbach, D; Coeck, S; Ryssens, W A M; Knoops, G; Vanbuel, J; Reiter, P; Miller, C; Martin sanchez-cano, D; Wiens, A; Blazhev, A A; Braun, N; Cappellazzo, M V; Birkenbach, B; Gerst, R; Dannhoff, M F; Sithole, M J; Bilgier, B; Nardelli, S; Vetter, U; Araujo mendes, C M; Agramunt ros, J; Valencia marin, E; Pantea, E; Hessberger, F P; Leduc, A J; Mitsuoka, S; Carbonari, A W; Buchegger, F J; Garzon camacho, A; Stachura, M K; Stora, T; Marsh, B A; Thiboud, J A; Antalic, S; Stahl, C; Bauer, C; Thurauf, M; Maass, B; Sturm, S; Boehm, C; Ways, M; Heylen, H; Riisager, K; Ruotsalainen, P A; Bastin, B; Duval, F T; Penessot, G; Flechard, X D; Desrues, P; Giovinazzo, J; Blank, B A; Kurtukian nieto, T; Ascher, P E L; Roccia, S; Matea, I; Croizet, H A G; Bonnin, C M; Morfouace, P; Smith, A J; Guin, R; Banerjee, D; Gunnlaugsson, H P; Ohtsubo, T; Zhukov, M V; Tengborn, E A; Dessagne, P; Juscamaita vivanco, Y; De rydt, M A E; Vermaelen, P; Monten, R; Yang, X; De coster, A; Kruecken, R; Nowak, A K; Cano ott, D; Murphy, A S J; Shand, C M; Regan, P H; Jones, G D; Herzberg, R; Ikin, P; Napoli, D R; Scarel, G; Larsen, A; Tornyi, T G; Pascu, S G; Stroe, L; Toma, S; Jansson, K; Dronjak fahlander, M; Krupko, S; Hurst, A M; Veskovic, M; Nikolov, J; Sibanda, W N; Rocchini, M; Klimo, J; Deicher, M; Wichert, T; Wolf, E; Kronenberg, J; Helmke, A; Meliani, Z; Ivanov, V S; Kuti, I; Halasz, Z; Henry, M O; Bras de sequeira amaral, V; Espirito santo, F; Da silva, D J; Carvalho teixeira, R C; Rosendahl, S; Speidel, K; Agarwal, I; Faul, T; Kownacki, J M; Martins correia, J G; Lorenz, K; Costa miranda, S M; Granadeiro costa, A R; Da costa pereira, L M; Keupers, M; Stukken, R; Wursten, E J; Kotthaus, T; Pfeiffer, M; Gironi, L; Cakirli, R B; Jensen, A; Romstedt, F; Constantino silva furtado, I; Heredia cardona, J A; Jordan martin, M D; Montaner piza, A; Zacate, M O; Plewinski, F; Mesli, A; Pichard, A; Hergemoller, F; Fallis starhunter, J P; Voulot, D; Mrazek, J; Ugryumov, V; Savreux, R P; Kojouharov, I M; Stegmann, R; Kern, R O; Fitting, J; Lauer, M; Kirsebom, O S; Jensen, K L; Jokinen, A; Rahkila, P J; Hager, U D K; Konki, J P; Dubois, M; Orr, N A; Fabian, X; Huikari, J E; Goigoux, T; Magron, C; Zakari, A A; Maietta, M; Bachelet, C E M; Roussiere, B; Li, R; Foster, R M; Mertzimekis, T; Gislason, H P; Shayestehaminzadeh, S; Qi, B; Mukai, M; Watanabe, Y; Willmann, L; Kurcewicz, W; Wimmer, K; Meisel, Z P; Dorvaux, O; Nowacki, F; Lievens, P; Neyens, G; Darby, I G; Descamps, B O; Ceruti, S; Bunka, M; Vermeulen, C; Umbricht, C A; De boer, J; Podadera aliseda, I; Alcorta moreno, M; Pesudo fortes, V; Zielinska, M; Korten, W; Wang, C H; Lotay, G J; Mason, P; Rice, S J; Willenegger, L M; Judson, D S; Revill, J P; Andreev, A; Yavuzkanat, N; Hass, M; Kumar, V; Crespo campo, L; Zamfir, N - V; Deleanu, D; Jeppesen, H B; Pain, S D; Stracener, D W; Matousek, V; Venhart, M; Birova, M; Li, X; Stuchbery, A E; Lellep, G M; Chakraborty, S; Leoni, S; Chupp, T; Yilmaz, C; Severin, G; Garcia ramos, J E; Hadinia, B; Mc glynn, E; Monteiro de sena silvares de carvalho, I; Friedag, P; Koos, V; Meot, V H; Pauwels, D B; Jancso, A; Srebrny, J; Alves, E J; David bosne, E; Dexters, W M M; Velten, P; Kalkuehler, M; Albers, M; Bharuth-ram, K; Akkus, B; Hemmingsen, L B S; Pedersen, J T; Dos santos redondo, L M; Rubio barroso, B; Algora, A; Kozlov, V; Mokhles gerami, A; Bernardo da silva, E; Unzueta solozabal, I; Schell, J; Szybowicz, M; Lassen, J; Johnston, K; Miyazaki, A; Macko, M; Coquard, L; Bloch, T P; Bonig, E S; Ignatov, A; Paschalis, S; Fernandez martinez, G; Schilling, M; Habermann, T; Von hahn, R; Minaya ramirez, E E; Manea, V; De roubin, A A J; Karthein, J; Moore, I D; Wang, Y; Saastamoinen, A J; Grahn, T; Herzan, A; Stolze, S M; Clement, E; Dijon, A; Shornikov, A; Lienard, E; Gibelin, J D; Pain, C; Canchel, G; Simpson, G S; Latrasse, L P; Huang, W; Forest, D H; Billowes, J; Flanagan, K; Strashnov, I; Binnersley, C L; Simpson, J; Morrall, P S; Grant, A F; Charisopoulos, S; Lagogiannis, A; Bhattacharya, C; Olafsson, S; Tornqvist, H T; Heinz, A M; White iv, E R; Vermote, S L; Courtin, S; Marechal, F; Randisi, G; Rajabali, M M; Lannoo, B J M; Frederickx, R; De coster, T J C; Roovers, N; De lemos lima, T A; Haller, S; Rizzi, M; Reichert, S B; Bonn, J; Thirolf, P G; Garcia rios, A R; Gugliermina, V M; Cubero campos, M A; Sanchez tembleque, V; Benito garcia, J; Senoville, M; Mountford, D J; Gelletly, W; Alharbi, T S T; Wilson, E; Rigby, S V; Andreoiu, C; Paul, E S; O'neill, G G; Harkness, L J; Wraith, C; Van esbroeck, K; Wadsworth, R; Cubiss, J G; Doherty, D T; Harding, R D; Vaintraub, S; Mandal, S K; Hadynska-klek, K; Scarpa, D; Hoff, P; Syed naeemul, H; Borcea, R; Balabanski, D L; Marginean, R; Rotaru, F; Rudolph, D; Fahlander, C H; Chudoba, V; Naidoo, D; Veselsky, M; Kliman, J; Raisanen, J A; Dietrich, M; Maung maung than, M M T; Reed, M W; Danchev, M T; Ray, J; Roy, M; Hammen, M; Capponi, L; Veghne csatlos, M M; Fryar, J; Mirzadeh vaghefi, S P; Trindade pereira, A M; Bakenecker, A; Tramm, C; Germic, V; Morel, P A; Kowalczyk, M; Matejska-minda, M; Ringvall moberg, A; Kana, T; Vermeeren, B R M; Dockx, K; Mantovan, R; Fransen, C H; Radeck, F; Schneiders, D W; Steinbach, T; Vibenholt, J E; Magnussen, M J; Stevnhoved, H M; Comas lijachev, V; Dasenbrock-gammon, N M; Perkowski, J; Matveev, Y; Wegner, M; Garcia borge, M J; Molholt, T E; Srnka, D; Dlouhy, Z; Beck, D; Homm, I; Eliseev, S; Blaum, K; Probst, M B; Kaiser, C J; Martin, J A; Refsgaard, J; Papadakis, F; Peura, P J; Greenlees, P T; Auranen, K; Delahaye, P; Traykov, E K; Perez loureiro, D; Mery, A A; Couratin, C; Tsekhanovich, I; Lunney, D; Gaulard, C V; Althubiti, N A S; Mottram, A D; Das, S K; Van de walle, J; Mazzocchi, C; Jonson, B N G; Woehr, A; Lesher, S R; Zuber, K T; Koudriavtsev, I; De witte, H J; Van den bergh, P A M; Raabe, R; Depuydt, M J F; Radulov, D P; Elseviers, J; Reynders, K L T; Sels, S M C; Verlinde, M; Delombaerde, L; De maesschalck, D; Dunlop, R A; Tarasava, K; Gernhaeuser, R A; Weinzierl, W; Berger, C; Wendt, K; Achtzehn, T; Gottwald, T; Schug, M; Rossel, R E; Dominguez reyes, R R; Briz monago, J A; Koester, U H; Bunce, M R; Bowry, M D; Nakhostin, M; Shearman, R; Cresswell, J R; Joss, D T; Gredley, A; Groombridge, D; Laird, A M; Aslanoglou, X; Siem, S; Weterings, J A; Renstrom, T; Szpak, B T; Luczkowski, M J; Ghita, D; Bezbakh, A; Bollmann, J; Bhattacharya, P; Roy, S; Rahaman, M A; Wlodarski, T; Carvalho soares, J; Barzakh, A; Werner, V R; Schertz, F; Froemmgen, N E; Liberati, V; Foy, B E; De pinho oliveira, G N; Weinheimer, C P; Zboril, M; Figuera, P; Simon, R E; Popescu, L A; Czosnyka, T; Miranda jana, P A; Buescher, J S L; Plociennik, W A; Ruchowska, E E; Chiara, C J; Eberth, J H; Thomas, T; Thole, P; Queiser, M T; Lo bianco, G; D'amico, F; Muller, S; Sanchez alarcon, R M; Tain enriquez, J L; Orrigo, S E A; Orlandi, R; Plazaola muguruza, F C; Pallada, S; Lepareur, N G; Wildner, E; Kowalska, M; Malbrunot, S; Slezak, M; Roeckl, E; Schrieder, G H; Ilieva, S K; Koenig, K L; Amoretti, M A; Lommen, J M; Fynbo, H O U; Weyer, G O P; Koldste, G T; Madsboll, K; Jensen, J H; Nieminen, A M; Reponen, M; Villari, A; Thomas, J; Saint-laurent, M; Sorlin, O H; Carniol, B; Pereira lopez, J; Grevy, S; Plaisir, C; Marie-jeanne, M J; Georgiev, G P; Etile, A M; Le blanc, F M; Verney, D; Stefan, G I; Assie, M; Suzuki, D; Guillot, J; Vazquez rodriguez, L; Campbell, P; Deacon, A N; Ware, T; Flueras, A; Xie, L; Banerjee, K; Piersa, M; Johansson, H T; Schwarz, S; Welker, A; Krauth, M R; Perrot, F; Aumont, J; Sferrazza, M; Van duppen, P L E; Versyck, S; Dehaes, J; Bree, N C F; Neyskens, P; Martinez palenzuela, Y; De groote, R P; Carlier, L M F; De schepper, S; Dewolf, K W A; Kabir, L R; Garcia ruiz, R F; Khodery ahmad, M A; Zadvornaya, A; Xu, Z; Smolders, P; Krastev, P; Rapisarda, E; Reber, J A; Mattolat, C F; Raeder, S; Habs, D; Martinez perez, T; Fraile prieto, L M; Vidal, M; Perez liva, M; Calvo portela, P; Ulla pedrera, F J; Wood, R T; Lalkovski, S; Page, R; Petri, M; Barton, C J; Nichols, A J; Vermeulen, M J; Bloor, D M; Henderson, J; Wilson, G L; De angelis, G; Buerger, A; Klintefjord, M L; Fornal, B A; Marginean, R; Sava, T; Suvaila, R; Lica, R; Costache, C; Mihai, R; Ionescu, A; Baeck, T M; Masenda, H; Sedlak, M; Koskelo, O K; Kyaw myat, K M; Ganguly, B; Goncalves marques, J; Cardoso, S; Seliverstov, M; Niessen, B D; Gutt, L E; Chapman, R; Spagnoletti, P N; Lopes, C; De oliveira amorim, C; Batista lopes, C M; Araujo, J; Schielke, S J; Daugas, J R; Gaudefroy, L; Chevrier, R; Szunyogh, D M; Napiorkowski, P J; Wrzosek-lipska, K; Wahl, U; Catarino, N; Pereira carvalho alves de sequeira, M; Decoster, S J; Porobic, T; Babo, M; Walters, W; Hess, H E; Holler, A; Bettermann, L; Geibel, K; Taprogge, J; Lewandowski, L T N; Manchado de sola, F; Das gupta, S; Thulstrup, P W; Heinz, U; Nogwanya, T; Neidherr, D M; Domingo pardo, C; Morales lopez, A I; Gumenyuk, O; Peaker, A R; Wakabayashi, Y; Abrahams, K J; Mach, H A; Souza ribeiro junior, I; He, J; Giles, T J; Dorsival, A; Kalaninova, Z; Venos, D; Kraemer, J; Saha, S; Neugart, R; Eronen, T O; Kreim, K D; Heck, M K; Goncharov, M; Julin, R J; Jakobsson, E H U; Eleon, C; Achouri, N L; Grinyer, G F; Fontbonne, C M; Alfaurt, P; Kusoglu, A; Wilkins, S G; Brown, A R; Imai, N; Pomorski, M J; Janiak, L; Nilsson, T; Stroke, H H; Stanja, J; Dangelser, E; Heenen, P; Mallion, S N; Diriken, J V J; Ghys, L H L; Khamehchi, M A; Van beveren, C; Gins, W A M; Bouma, J T; Koszorus, A; Mcnulty, J F; Ohlert, C M; Schwerdtfeger, W; Tengblad, O; Becerril reyes, A D; Perea martinez, A; Martinez perez, M C; Margerin, V; Rudigier, M; Alexander, T D; Patel, Z V; Hammond, N; Wearing, F; Patel, A; Jenkins, D G; Debernardi, A; Giacoppo, F; Tveten, G M; Malatji, K L; Krolas, W A; Stanoiu, M A; Rickert, E U; Ter-akopian, G; Cline, D; Riihimaeki, I A; Simon, K D; Wagner, F E; Turker, M; Neef, M H; Jakubek, J; Vagena, E; Bottoni, S; Nishimura, K; Correia, J; Rodrigues valdrez, C J; Ostrowski, A N; Hallmann, O; Scheck, M; Wady, P T; Lane, J; Krasznahorkay, A J; Kunne sohler, D; Meaney, A J; Baptista barbosa, M; Hochschulz, F; Roig, O; Houngbo, D; Behan, C C; Kargoll, S; Kemnitz, S; Redondo cubero, A; Dirkx, D; Stegemann, S T; Tallarida, G; Kaczarowski, R; Finke, F; Linnemann, A; Altenkirch, R; Saed-samii, N; Ansari, S H; Dlamini, W B; Adoons, V N; Ronning, C R; Wiedeking, M; Guadilla gomez, V; Herlert, A J; Mehl, C V; Judge, S M; Catherall, R; Lettry, J; Wenander, F J C; Zakoucky, D; Catchen, G L; Noertershaeuser, W; Kroell, T; Leske, J; Shubina, D; Murray, I M; Pancin, J; Delaunay, F; Poincheval, J J L; Audirac, L L; Gerbaux, M T; Aouadi, M; Sole, P G P; Fallot, M P; Onillon, A; Duchemin, C; Formento cavaier, R; Audi, G; Boukhari, A; Lau, C; Martin, J A; Barre, N H; Berry, T A; Procter, T J; Farooq-smith, G J; Bladen, L K; Axiotis, M; Muto, S; Jeong, S C; Hirayama, Y; Korgul, A B; Minamisono, K; Bingham, C R; Aprahamian, A; Bucher, B M; Huyse, M L; Himpe, P; Ferrer garcia, R; Sambi, S; Budincevic, I; Neven, M; Bomans, P; Romano, N; Maugeri, E A; Klupp, S C; Dehn, M H; Heinke, R M; Naubereit, P; Maira vidal, A; Vedia fernandez, M V; Ibanez garcia, P B; Bruyneel, B J E; Materna, T; Al-dahan, N; Alazemi, N; Carroll, R J; Babcock, C; Eleme, Z; Dhal, A; Valiente dobon, J J; Sahin, E; Goergen, A; Maj, A; Bednarczyk, P A; Borcea, C; Negoita, F; Suliman, G; Marginean, N M; Sotty, C O; Negret, A L; Nae, S A; Nita, C; Golubev, P I; Knyazev, A; Jost, C U; Petrik, K; Strisovska, J; Vaeyrynen, S A; Dracoulis, G D; Uher, J; Fernandez dominguez, B; Chakraborty, P; Avigo, R; Galaviz redondo, D; Castro ribeiro da silva, M; Bernards, C W; Falahat, S; Lekovic, F; Dorrer, H J; Derkx, X; Angus, L J; Sandhu, K S; Gregor, E; Byrne, D J; Haas, H; Lourenco, A A; Sousa pereira, S M; Sousa, J B; De melo mendonca, T M; Tavares de sousa, C; Guerreiro dos santos oliveira custodio, L M; Da rocha rodrigues, P M; Yamaguchi, T; Thompson, P C; Rosenbusch, M; Wienholtz, F; Fischer, P; Iwanicki, J S; Rusek, K M; Hanstorp, D; Severijns, N; Vanpoucke, B R S; Finlay, P E J; Park, S H; Warr, N V; Doornenbal, P C; Imig, A; Seidlitz, M; Moschner, K; Vogt, A; Kaya, L; Martel bravo, I; Orduz, A K; Serot, O; Majola, S N; Litvinov, Y; Bommert, M; Hensel, S; Markevich, V; Nishio, K; Ota, S; Matos, I; Zenkevich, A; Picado sandi, E; Forstner, O

    2002-01-01

    The experiments aim at a broad exploration of the properties of atomic nuclei far away from the region of beta stability. Furthermore, the unique radioactive beams of over 60~elements produced at the on-line isotope separators ISOLDE-2 and ISOLDE-3 are used in a wide programme of atomic, solid state and surface physics. Around 300 scientists are involved in the project, coming from about 70 laboratories. \\\\ \\\\ The electromagnetic isotope separators are connected on-line with their production targets in the extracted 600 MeV proton or 910~MeV Helium-3 beam of the Synchro-Cyclotron. Secondary beams of radioactive isotopes are available at the facility in intensities of 10$^1

  20. Enresa's Participation in the Technical Assistance Programmes to the Eastern European Countries

    Energy Technology Data Exchange (ETDEWEB)

    Beceiro, A. R.; Vico, E. [ENRESA. Madrid (Spain)

    2000-07-01

    This article briefly describes the participation of ENRESA in the technical assistance programmes to the Central and Eastern European countries (PHARE) and to the New Independent States (TACIS) as well as in the co-operation programmes all of them established by the European Commission. It is worth to point out the active role of ENRESA within the European Consortium CASSIOPEE, formed in 1993 by the six radioactive waste management companies in existence in the European Union at that time. CASSIOPEE was created to assist the European Commission in the area of radioactive waste management of the PHARE and TACIS technical assistance programmes. (Author)

  1. Effectiveness of a Universal Parental Support Programme to Promote Healthy Dietary Habits and Physical Activity and to Prevent Overweight and Obesity in 6-Year-Old Children: The Healthy School Start Study, a Cluster-Randomised Controlled Trial: e0116876

    National Research Council Canada - National Science Library

    Gisela Nyberg; Elinor Sundblom; Åsa Norman; Benjamin Bohman; Jan Hagberg; Liselotte Schäfer Elinder

    2015-01-01

      Objective To develop and evaluate the effectiveness of a parental support programme to promote healthy dietary and physical activity habits and to prevent overweight and obesity in Swedish children...

  2. Establishment of testis-specific SOX9 activation requires high-glucose metabolism in mouse sex differentiation.

    Science.gov (United States)

    Matoba, Shogo; Hiramatsu, Ryuji; Kanai-Azuma, Masami; Tsunekawa, Naoki; Harikae, Kyoko; Kawakami, Hayato; Kurohmaru, Masamichi; Kanai, Yoshiakira

    2008-12-01

    In mouse sex differentiation, SRY promotes Sertoli cell differentiation via SOX9 action, resulting in testis formation. SRY/SOX9 also initiates various testis-specific morphogenic events including glycogenesis in pre-Sertoli cells, suggesting the importance of glucose storage for certain SRY/SOX9-downstream events in gonadal sex determination. However, it remains unclear which cell types and what molecular/cellular events require sex-dimorphic high-energy metabolic rate. Here we show that the establishment of SOX9 activation itself is a metabolically active process with sex-dimorphic high-energy requirements in gonadal sex differentiation. The glucose-deprivation and metabolic rescue experiments using genital ridge cultures of the XY/XX-wildtype and XX/Sry transgenic embryos demonstrated that, among the various somatic cell types, pre-Sertoli cells are the most sensitive to glucose starvation despite the differences between XX/Sry and XY genotypes. Moreover, our data showed that, in developing pre-Sertoli cells, the high-glucose metabolic state is required for the establishment of SOX9 expression through an ECM (extracellular matrix)-mediated feed-forward pathway. In contrast, the expression of SRY, SF1/Ad4Bp, GATA4 and WT1, as well as initiation of early SOX9 expression, is properly maintained in the glucose-deprived condition. Therefore, our results imply the metabolic importance of the high-glucose condition for the establishment of SOX9 activation in testis differentiation.

  3. Association between activity space exposure to food establishments and individual risk of overweight.

    Directory of Open Access Journals (Sweden)

    Yan Kestens

    Full Text Available OBJECTIVE: Environmental exposure to food sources may underpin area level differences in individual risk for overweight. Place of residence is generally used to assess neighbourhood exposure. Yet, because people are mobile, multiple exposures should be accounted for to assess the relation between food environments and overweight. Unfortunately, mobility data is often missing from health surveys. We hereby test the feasibility of linking travel survey data with food listings to derive food store exposure predictors of overweight among health survey participants. METHODS: Food environment exposure measures accounting for non-residential activity places (activity spaces were computed and modelled in Montreal and Quebec City, Canada, using travel surveys and food store listings. Models were then used to predict activity space food exposures for 5,578 participants of the Canadian Community Health Survey. These food exposure estimates, accounting for daily mobility, were used to model self-reported overweight in a multilevel framework. Median Odd Ratios were used to assess the proportion of between-neighborhood variance explained by such food exposure predictors. RESULTS: Estimates of food environment exposure accounting for both residential and non-residential destinations were significantly and more strongly associated with overweight than residential-only measures of exposure for men. For women, residential exposures were more strongly associated with overweight than non-residential exposures. In Montreal, adjusted models showed men in the highest quartile of exposure to food stores were at lesser risk of being overweight considering exposure to restaurants (OR = 0.36 [0.21-0.62], fast food outlets (0.48 [0.30-0.79], or corner stores (0.52 [0.35-0.78]. Conversely, men experiencing the highest proportion of restaurants being fast-food outlets were at higher risk of being overweight (2.07 [1.25-3.42]. Women experiencing higher residential exposures

  4. Self-reported physical activity and major adverse events in patients with atrial fibrillation: a report from the EURObservational Research Programme Pilot Survey on Atrial Fibrillation (EORP-AF) General Registry.

    Science.gov (United States)

    Proietti, Marco; Boriani, Giuseppe; Laroche, Cécile; Diemberger, Igor; Popescu, Mircea I; Rasmussen, Lars H; Sinagra, Gianfranco; Dan, Gheorghe-Andrei; Maggioni, Aldo P; Tavazzi, Luigi; Lane, Deirdre A; Lip, Gregory Y H

    2017-04-01

    Physical activity is protective against cardiovascular (CV) events, both in general population and in high-risk CV cohorts. However, the relationship between physical activity with major adverse outcomes in atrial fibrillation (AF) is not well-established. Our aim was to analyse this relationship in a 'real-world' AF population. Second, we investigated the influence of physical activity on arrhythmia progression. We studied all patients enrolled in the EURObservational Research Programme on AF (EORP-AF) Pilot Survey. Physical activity was defined as 'none', 'occasional', 'regular', and 'intense', based on patient self-reporting. Data on physical activity were available for 2442 patients: 38.9% reported none, 34.7% occasional, 21.7% regular, and 4.7% intense physical activity. Prevalence of the principal CV risk factors progressively decreased from none to intense physical activity. Lower rates of CV death, all-cause death, and composite outcomes were found in AF patients who reported regular and intense physical activity (P < 0.0001). Increasing physical activity was inversely associated with CV death/any thromboembolic event (TE)/bleeding in the whole cohort, irrespective of gender, paroxysmal AF, elderly age, or high stroke risk. Any level of physical activity intensity was significantly associated with lower risk of CV death/any TE/bleeding at 1-year follow-up. Physical activity was not significantly associated with arrhythmia progression. Atrial fibrillation patients taking regular exercise were associated with a lower risk of all-cause death, even when we considered various subgroups, including gender, elderly age, symptomatic status, and stroke risk class. Efforts to increase physical activity among AF patients may improve outcomes in these patients.

  5. CASINDO Programme Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Van der Linden, N.; Smekens, K.; Bole-Rentel, T.; Saidi, R. [Unit ECN Policy Studies, Energy research Centre of the Netherlands ECN, Petten (Netherlands); Wijnker, M. [Eindhoven University of Technology TUE, Eindhoven (Netherlands); Kamphuis, E. [ETC Netherlands, Leusden (Netherlands); Winarno, Oetomo Tri [Institute of Technology, Bandung (Indonesia); Permana, Iman [Technical Education Development Centre, Bandung (Indonesia)

    2012-06-15

    The overall objective of the CASINDO programme is to establish a self-sustaining and self-developing structure at both the national and regional level to build and strengthen human capacity to enable the provinces of North Sumatra, Yogyakarta, Central Java, West Nusa Tenggara and Papua to formulate sound policies for renewable energy and energy efficiency and to develop and implement sustainable energy projects. CASINDO stands for Capacity development and strenghtening for energy policy formulation adn implementation of sustainable energy projects in Indonesia.

  6. Leishmania lipophosphoglycan: how to establish structure-activity relationships for this highly complex and multifunctional glycoconjugate?

    Directory of Open Access Journals (Sweden)

    Claire-Lise eForestier

    2015-01-01

    Full Text Available A key feature of many pathogenic microorganisms is the presence of a dense glycocalyx at their surface, composed of lipid-anchored glycoproteins and non-protein-bound polysaccharides. These surface glycolipids are important virulence factors for bacterial, fungal and protozoan pathogens. The highly complex glycoconjugate lipophosphoglycan (LPG is one of the dominant surface macromolecules of the promastigote stage of all Leishmania parasitic species. LPG plays critical pleiotropic roles in parasite survival and infectivity in both the sandfly vector and the mammalian host. Here, we review the composition of the Leishmania glycocalyx, the chemical structure of LPG and what is currently known about its effects in the mammalian host, specifically. We will then discuss the current approaches employed to elucidate LPG functions. Finally, we will provide a viewpoint on future directions that this area of investigation could take to unravel in detail the biological activity of the specific molecular elements composing the structurally complex LPG.

  7. Establishing `fields of care': teaching settings as active participants in science education

    Science.gov (United States)

    Blatt, Erica N.

    2014-03-01

    In their article, "Space, relations, and the learning of science," Wolff-Michael Roth and Pei-Ling Hsu draw our attention to the importance of field in the teaching and learning of science. While the Roth and Hsu study is focused on the scientific research laboratory as an internship setting for the teaching of science, this response to their paper expands the discussion of the settings where science is taught in order to bring to the fore some of the affordances and challenges associated with teaching science in specific fields. By extending our thinking about the settings where science is taught/learned and the active role these settings play in teaching our students, we can re-envision how to better utilize a variety of fields in the teaching of science. The notion of `field of care' is explored as a way of both finding and building connections between students and the settings where science is experienced.

  8. Surface activity distribution measurements and establishment of a dose rate map inside the destroyed Chernobyl reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chesnokov, A.V.; Fedin, V.I.; Gulyaev, A.A. [RECOM Ltd., Moscow (Russian Federation)] [and others

    1999-02-01

    A Gamma Locator designed for contamination survey inside the reactor hall of the 4th unit of Chernobyl NNP has been developed. The device consists of a detector head and a remote control computer connected by a 150 m long cable. The detector head (dimensions: 500 mm by 500 mm by 400 mm; weight: about 40 kg) is a collimated scintillation gamma detector (the collimation angle is 10 deg.). It is installed on a scanning unit and was placed inside the reactor hall. The Gamma Locator scans all surfaces of the reactor hall with angular steps ({<=} 1 deg. vertically as well as horizontally) and the particle fluence from the corresponding direction is recorded. The distance between the device head and the measured surface is instantaneously registered by a laser distance gauge. Inside the collimator there is a small CCD camera which makes it possible to obtain a visible image of the measured surface. The effective surface activity levels are presented in colour on the screen of the control computer. The gamma detector essentially consists of a CsI(TI) scintillator crystal ({phi} 8 mm in diameter, 2.5 mm in thickness) and a Si photodiode. The detector energy resolution is about 8% for radiation from {sup 137}Cs. The exposure dose rate distribution in the reactor hall is estimated from the measured effective surface activities ({sup 137}Cs is the main gamma emitting isotope inside the reactor hall). The results of dose rate calculations are presented in colour superposed on a drawing of the reactor hall. (au) 1 tab., 28 ills., 16 refs.

  9. Identification of active Plasmodium falciparum calpain to establish screening system for Pf-calpain-based drug development

    Directory of Open Access Journals (Sweden)

    Soh Byoung

    2013-02-01

    Full Text Available Abstract Background With the increasing resistance of malaria parasites to available drugs, there is an urgent demand to develop new anti-malarial drugs. Calpain inhibitor, ALLN, is proposed to inhibit parasite proliferation by suppressing haemoglobin degradation. This provides Plasmodium calpain as a potential target for drug development. Pf-calpain, a cysteine protease of Plasmodium falciparum, belongs to calpain-7 family, which is an atypical calpain not harboring Ca2+-binding regulatory motifs. In this present study, in order to establish the screening system for Pf-calpain specific inhibitors, the active form of Pf-calpain was first identified. Methods Recombinant Pf-calpain including catalytic subdomain IIa (rPfcal-IIa was heterologously expressed and purified. Enzymatic activity was determined by both fluorogenic substrate assay and gelatin zymography. Molecular homology modeling was carried out to address the activation mode of Pf-calpain in the aspect of structural moiety. Results Based on the measurement of enzymatic activity and protease inhibitor assay, it was found that the active form of Pf-calpain only contains the catalytic subdomain IIa, suggesting that Pf-calpain may function as a monomeric form. The sequence prediction indicates that the catalytic subdomain IIa contains all amino acid residues necessary for catalytic triad (Cys-His-Asn formation. Molecular modeling suggests that the Pf-calpain subdomain IIa makes an active site, holding the catalytic triad residues in their appropriate orientation for catalysis. The mutation analysis further supports that those amino acid residues are functional and have enzymatic activity. Conclusion The identified active form of Pf-calpain could be utilized to establish high-throughput screening system for Pf-calpain inhibitors. Due to its unique monomeric structural property, Pf-calpain could be served as a novel anti-malarial drug target, which has a high specificity for malaria parasite

  10. Sale leisure activities of children and youth in out of school educational establishments of physical culture and sports destinations

    Directory of Open Access Journals (Sweden)

    Tikhonova N.V.

    2014-10-01

    Full Text Available Purpose : To determine the role of extracurricular educational establishments of physical culture sports direction in providing leisure activities for children and youth. Material : The results of the analysis of the scientific and methodological literature, statistical reports of the Ministry of Youth and Sports of Ukraine, authorities of Physical Culture and Sport, authorities the Department of Education and Science. Results : Based on the analysis of statistical reports determined satisfactory condition and leisure activities in non-school educational establishments physical culture sports direction. This is confirmed by an increase in the number of pupils and students dealing all kinds of physical culture health improvement work. Also, the decline in the number of pupils and students classified for health reasons for the special medical group. Conclusions : Our data showed that extracurricular educational institutions physical culture sports direction have a place in leisure activities. They play an important role in motor activity, substantial leisure and healthy lifestyles for children and young people of our country.

  11. READINESS OF TEACHERS FOR THE ORGANIZATION OF EXTRACURRICULAR ACTIVITIES OF STUDENTS AT HIGHER EDUCATIONAL ESTABLISHMENT OF ECONOMICS

    Directory of Open Access Journals (Sweden)

    L. V. Vishnevetskaja

    2014-09-01

    Full Text Available The urgency of the article, its theoretical and practical importance are caused by the existing contradiction between the state order for the formation of socially active person and lack of scientifically-practical workings out in the field of pedagogical support of the organization of extracurricular socially useful activity of the students. The settlement of the contradiction is possible in the presence of teachers specially prepared for the given process.Purpose. The purpose of the article is the theoretical substantiation and experimental estimation of teachers’ readiness for the organization of extracurricular activities of students in higher education establishments of economics.Methodology, Results. Complex application of theoretical (element and the structural analysis, comparison, generalization and empirical (questioning, testing, the expert estimation, included pedagogical supervision methods has allowed to define the essence of investigated concept as integrative personal formation, to develop criteria and its indicators of its formation and experimentally estimate the level of readiness of teaching staff for the organization of students’ extracurricular activities in higher education establishments of economics.Practical implications. The results of the research can be widely used in the work of curators of academic groups, tutors, teachers-organizers, in the system of training and advanced training of teaching staff.

  12. Does a physiotherapy programme of gross motor training influence motor function and activities of daily living in children presenting with developmental coordination disorder?

    Directory of Open Access Journals (Sweden)

    Sonill S. Maharaj

    2016-02-01

    Full Text Available Background: Children with developmental coordination disorder (DCD lack motor coordination and have difficulty performing motor skills and activities of daily living. Research shows these children do not outgrow their motor difficulties and without intervention do not improve. Physiotherapy is relevant for these children, but due to limited clinical protocols for DCD the aim of this study was to determine the effect of a gross motor training programme for 6–12-year-old children with DCD.Methods: This randomised pre-test, post-test study recruited 64 children with scores of 15th percentile or below using the Movement Assessment Battery for Children (M-ABC. The children were divided equally into an intervention group receiving 8 weeks of gross motor training for core stability, strengthening exercises, balance and coordination with task-specific activities for 30 min per week, while the control group continued with general therapy and activities of daily living. The M-ABC and Developmental Coordination Disorder Questionnaire (DCDQ were used to assess each child before and after 8 weeks.Results: Sixty children completed the study, with 43 males and 17 females (mean age 10.02 years, SD = 2.10. There were no adverse reactions to the programme and M-ABC scores for the intervention programme improved by 6.46%, ball skills (3.54% and balance (4.80% compared with the control (0.17% and (0.15%, respectively. There were significant (p < 0.05 improvements in DCDQ scores, but teachers allocated lower scores than parents.Conclusion: This study supports 8 weeks of gross motor training which can be a beneficial intervention for physiotherapists to improve gross motor function for DCD.Keywords: Developmental, co-ordination, skills, motor

  13. The Back 2 Activity Trial: education and advice versus education and advice plus a structured walking programme for chronic low back pain

    Directory of Open Access Journals (Sweden)

    Bradbury Ian

    2010-07-01

    Full Text Available Abstract Background Current evidence supports the use of exercise-based treatment for chronic low back pain that encourages the patient to assume an active role in their recovery. Walking has been shown it to be an acceptable type of exercise with a low risk of injury. However, it is not known whether structured physical activity programmes are any more effective than giving advice to remain active. Methods/Design The proposed study will test the feasibility of using a pedometer-driven walking programme, as an adjunct to a standard education and advice session in participants with chronic low back pain. Fifty adult participants will be recruited via a number of different sources. Baseline outcome measures including self reported function; objective physical activity levels; fear-avoidance beliefs and health-related quality of life will be recorded. Eligible participants will be randomly allocated under strict, double blind conditions to one of two treatments groups. Participants in group A will receive a single education and advice session with a physiotherapist based on the content of the 'Back Book'. Participants in group B will receive the same education and advice session. In addition, they will also receive a graded pedometer-driven walking programme prescribed by the physiotherapist. Follow up outcomes will be recorded by the same researcher, who will remain blinded to group allocation, at eight weeks and six months post randomisation. A qualitative exploration of participants' perception of walking will also be examined by use of focus groups at the end of the intervention. As a feasibility study, treatment effects will be represented by point estimates and confidence intervals. The assessment of participant satisfaction will be tabulated, as will adherence levels and any recorded difficulties or adverse events experienced by the participants or therapists. This information will be used to modify the planned interventions to be used in a

  14. Bioergia Research Programme

    Energy Technology Data Exchange (ETDEWEB)

    Asplund, D.

    1997-12-31

    The main objectives of Finland`s Bioenergia Research Programme are (1) To develop new methods of producing biofuels which can compete with imported fuels, demonstrating the most promising production methods through pilot schemes, (2) To develop and demonstrate 3 - 4 new pieces of equipment or methods connected with handling and using bioenergy, (3) To produce basic information on conversion techniques and evaluate the quality, usability and environmental impacts of the products as well as the overall economy of the entire production chain and to create 2-3 conversion methods for follow-up development by industry. The principle research areas are (1) Development of production technology for wood-derived fuels, (2) Peat production, (3) The use of bioenergy and (4) Biomass conversion. This conference paper discusses the results obtained so far and reviews in some detail the activities of the programme. 3 figs., 3 tabs.

  15. Technical proposal for including health in the procedures for assessing the environmental impact of policies, plans, programmes, projects and activities

    Directory of Open Access Journals (Sweden)

    Almudena García Nieto

    2015-05-01

    Full Text Available Health was an element of general licensing procedures until Spain joined the EU in 1986, when the health report became diluted. The purpose of this article is to provide an overview of this topic’s current regulatory framework and to try to briefly describe health priorities and the channels for feasibly integrating the health variable in the environmental assessment of plans, programmes and projects from the public and private sectors. The current existence of the Environmental Assessment Act and the Public Health Act may help to achieve this.When preparing a strategic environmental study and an environmental impact study, the health impact assessment should be considered an essential step in these environmental procedures and have the same legal treatment as the “compulsory and determinant reports” of said procedures.Thus, it is concluded that the regulatory development of the aspects relating to the assessment of the health impact of the plans, programmes and projects envisaged in the Environmental Assessment Act is essential, the health impact assessment being the tool for doing so.

  16. The HAT TRICK programme for improving physical activity, healthy eating and connectedness among overweight, inactive men: study protocol of a pragmatic feasibility trial.

    Science.gov (United States)

    Caperchione, Cristina M; Bottorff, Joan L; Oliffe, John L; Johnson, Steven T; Hunt, Kate; Sharp, Paul; Fitzpatrick, Kayla M; Price, Ryley; Goldenberg, S Larry

    2017-09-06

    Physical activity, healthy eating and maintaining a healthy weight are associated with reduced risk of cardiovascular disease, type 2 diabetes and cancer and with improved mental health. Despite these benefits, many men do not meet recommended physical activity guidelines and have poor eating behaviours. Many health promotion programmes hold little appeal to men and consequently fail to influence men's health practices. HAT TRICK was designed as a 12-week face-to-face, gender-sensitised intervention for overweight and inactive men focusing on physical activity, healthy eating and social connectedness and was delivered in collaboration with a major junior Canadian ice hockey team (age range 16-20 years). The programme was implemented and evaluated to assess its feasibility. This article describes the intervention design and study protocol of HAT TRICK. HAT TRICK participants (n=60) were men age 35 years, residing in the Okanagan Region of British Columbia, who accumulate 150 min of moderate to vigorous physical activity a week, with a body mass index of >25 kg/m(2) and a pant waist size of >38'. Each 90 min weekly session included targeted health education and theory-guided behavioural change techniques, as well as a progressive (ie, an increase in duration and intensity) group physical activity component. Outcome measures were collected at baseline, 12 weeks and 9 months and included the following: objectively measured anthropometrics, blood pressure, heart rate, physical activity and sedentary behaviour, as well as self-reported physical activity, sedentary behaviour, diet, smoking, alcohol consumption, sleep habits, risk of depression, health-related quality of life and social connectedness. Programme feasibility data (eg, recruitment, satisfaction, adherence, content delivery) were assessed at 12 weeks via interviews and self-report. Ethical approval was obtained from the University of British Columbia Okanagan Behavioural Research Ethics Board (reference no H

  17. The (cost-effectiveness of an individually tailored long-term worksite health promotion programme on physical activity and nutrition: design of a pragmatic cluster randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Burdorf Alex

    2007-09-01

    Full Text Available Abstract Background Cardiovascular disease is the leading cause of disability and mortality in most Western countries. The prevalence of several risk factors, most notably low physical activity and poor nutrition, is very high. Therefore, lifestyle behaviour changes are of great importance. The worksite offers an efficient structure to reach large groups and to make use of a natural social network. This study investigates a worksite health promotion programme with individually tailored advice in physical activity and nutrition and individual counselling to increase compliance with lifestyle recommendations and sustainability of a healthy lifestyle. Methods/Design The study is a pragmatic cluster randomised controlled trial with the worksite as the unit of randomisation. All workers will receive a standard worksite health promotion program. Additionally, the intervention group will receive access to an individual Health Portal consisting of four critical features: a computer-tailored advice, a monitoring function, a personal coach, and opportunities to contact professionals at request. Participants are employees working for companies in the Netherlands, being literate enough to read and understand simple Internet-based messages in the Dutch language. A questionnaire to assess primary outcomes (compliance with national recommendations on physical activity and on fruit and vegetable intake will take place at baseline and after 12 and 24 months. This questionnaire also assesses secondary outcomes including fat intake, self-efficacy and self-perceived barriers on physical activity and fruit and vegetable intake. Other secondary outcomes, including a cardiovascular risk profile and physical fitness, will be measured at baseline and after 24 months. Apart from the effect evaluation, a process evaluation will be carried out to gain insight into participation and adherence to the worksite health promotion programme. A cost-effectiveness analysis and

  18. Expanded Programme on Immunization in Iran: Last 3 Decades Achievements from 1979 to 2008

    Directory of Open Access Journals (Sweden)

    MM Gouya

    2009-03-01

    Full Text Available "nExpanded Programme on Immunization (EPI in I.R.Iran began in 1984 after establishing of health network for PHC all over the country and reached to high & accepted coverage rates for active immunization of infants against vaccine prevent­able diseases including Diphteria, Tetanus, Pertussis, Measles, Poliomyelitis and Tuberculosis.

  19. An active factor from tomato root exudates plays an important role in efficient establishment of mycorrhizal symbiosis.

    Directory of Open Access Journals (Sweden)

    Shubin Sun

    Full Text Available Root exudates play an important role in the early signal exchange between host plants and arbuscular mycorrhizal fungi. M161, a pre-mycorrhizal infection (pmi mutant of the tomoto (Solanum lycopersicum cultivar Micro-Tom, fails to establish normal arbuscular mycorrhizal symbioses, and produces exudates that are unable to stimulate hyphal growth and branching of Glomus intraradices. Here, we report the identification of a purified active factor (AF that is present in the root exudates of wild-type tomato, but absent in those of M161. A complementation assay using the dual root organ culture system showed that the AF could induce fungal growth and branching at the pre-infection stage and, subsequently, the formation of viable new spores in the M161 background. Since the AF-mediated stimulation of hyphal growth and branching requires the presence of the M161 root, our data suggest that the AF is essential but not sufficient for hyphal growth and branching. We propose that the AF, which remains to be chemically determined, represents a plant signal molecule that plays an important role in the efficient establishment of mycorrhizal symbioses.

  20. Programme news: agencies report on their activities in nutrition. How is interagency coordination in countries actually meant to work?

    Science.gov (United States)

    1997-12-01

    United Nations Administrative Committee on Coordination representatives have been urged to establish thematic groups to facilitate interagency coordination in their countries. By 1996, there were only six countries--Angola, Kuwait, Libya, Saudi Arabia, Afghanistan, and North Korea--that had not yet established such groups. In addition to information exchange and networking, thematic groups have focused on joint programming, development of sector plans, and resource mobilization. Four clusters of themes exist: food security and agriculture, health and population, poverty, and HIV. Remaining is a need to operationalize technical strategies and agency agendas, translate cross-sectoral priorities into sectoral priorities, and evaluate ongoing programs.

  1. Evaluation of support for non-agricultural activities in Slovakia in the period 2007-2013 through the Rural Development Programme 2007-2013

    Directory of Open Access Journals (Sweden)

    Zuzana BOHATOVA

    2016-06-01

    Full Text Available Rural Development Programme of the SR (RDP SR 2007-2013 represented a comprehensive programme document for funding from the European Agricultural Fund for Rural Development (EAFRD in the programming period 2007-2013. The RDP SR 2007-2013 supported many activities related to agriculture, forestry industry, livestock production, tourism and agro-tourism. Following goals of the EAFRD were supported by the RDP SR 2007-2013: Increasing the competitiveness of agriculture, food and forestry sector; Improving the environment and landscape; Improvement of life in rural areas and Diversification of the rural economy. The last mentioned activity: Diversification of the rural economy was supported in the previous programming period by the Axis 3: Quality of life in rural areas, Measure 3.1. Diversification into non-agricultural activities. The objective of this paper is to evaluate the implementation of the Measure 3.1. The paper focuses on content evaluation of supported projects and spatial and financial allocation of request for non-repayable financial contribution. The first part of the paper is focused on the submission of request for non-repayable financial contribution: call for proposals, supported documents available for applicants, preparation of projects and their submission. The second part of the paper is oriented on evaluation of submitted projects by the Agricultural Paying Agency and payments for beneficiaries. The third part of the paper is oriented on evaluation of realization of projects with emphasis on problems on both sides: on the side of beneficiaries and on the side of the Agricultural Paying Agency. The goal of the paper is to show problems which occurred in all phases of realization of projects under the measure 3.1 with the aim to avoid the appearance of the same problems in following programming periods.

  2. Radiation research within the framework programmes of the European Commission

    Energy Technology Data Exchange (ETDEWEB)

    Karaoglou, A.; Kelly, G.N.; Desmet, G.; Menzel, H.G.; Schibilla, H.; Olast, M.; Gasperini, F.; Chadwick, K.H.; Sinnave, J. [European Commission Directorate General science, Brussels (Belgium). Research and Development, Radiation Protection Research Action

    1997-09-01

    The background to the radiation protection research and training programme of the European Commission is described in the presentation. The objectives and achievements of the third framework programme are summarised together with a description of how the achievements led to the establishment of the priorities for the fourth framework programme. Indications on the preliminary prospects for the fifth framework programme, 1998-2002 are also given. (6 refs.).

  3. Modelling Landscape Dynamics in a Highland Mediterranean Catchment: Establishing the impact of Climate Variation and Human Activity

    Science.gov (United States)

    van Beek, L. P. H.; Feiken, H.; van Asch, T. W. J.; Bierkens, M. F. P.

    2012-04-01

    The close link between human occupancy and the Mediterranean landscape has long been recognized. Through the exploitation of the various but fragmented resources that these landscapes have to offer, man has been able to secure a living. However, these activities are often marginal and small shifts in population pressure, corresponding land use patterns or climatic variability can have large consequences on the redistribution of water and sediment in these areas. The meso-scale landscape dynamics model, CALEROS, has been developed to simulate the interactions between climate, soil production and erosion, vegetation and land use on geomorphological to human time scales in Mediterranean environments. Starting from an initial landscape consisting of a DTM, soil distribution and underlying lithology, the landscape is free to develop in response to the imposed climate variability and seismicity. In addition to changes in soil distribution and bedrock lowering, this includes the establishment of vegetation as conditioned by a selection of plant functional types and, optionally, population and land use dynamics as conditioned by land use scenarios specifying technological and dietary constraints for different periods. As such CALEROS is well-suited to investigate the relative impacts of climate, land cover and human activities on the hydrological catchment response and the associated sediment fluxes due to soil erosion and mass movements. Within the context of a geo-archeological study on the conservation potential of settlement history in the Contrada Maddalena (~14km2, Calabria, Italy), we apply CALEROS to investigate the relative contributions of climate and man from Neolithic times onwards (5000 BP-present). Model results allow to establish when human impacts become significant over natural variations and to discern shifts in catchment functioning as a result of sudden or climatic variations (e.g., Little Ice Age) as reflected in vegetation patterns and water and

  4. Going global in physical therapist education: International Service-Learning in US-based programmes.

    Science.gov (United States)

    Pechak, Celia; Thompson, Mary

    2011-12-01

     Internationalization is expanding its presence in higher education in the United States. Reflecting this trend that includes incorporating global perspectives in the curricula, physical therapist education programmes increasingly offer international opportunities such as International Service-Learning (ISL) to their students. Service-learning, a teaching strategy that integrates community service with structured learning activities, has gained broad acceptance in health professions education including physical therapy, and is therefore the focus of this paper. The specific purposes of this paper were to identify and analyse the commonalities that existed among established ISL programmes within physical therapist education programmes in terms of structures and processes, and to consider its broader implications for physical therapist education.   A descriptive, exploratory study was performed using grounded theory. Snowball and purposive, theoretical sampling yielded 14 faculty members with experience in international service, international learning or ISL in physical therapist education programmes. Faculty were interviewed by phone. Interview transcriptions and course documents were analysed applying grounded theory methodology. Data from eight programmes which met the operational definition of established ISL were used to address the purposes of this paper.   Five phases of establishing an ISL programme were identified: development, design, implementation, evaluation, and enhancement. Although no single model exists for ISL in physical therapist education; commonalities in structures and processes were identified in each phase. However, attention to service objectives and outcomes is lacking.   While analysis revealed that each programme shared commonalities and demonstrated differences in structures and processes compared with the other programmes, the study demonstrated a general lack of focus on formal community outcomes which raises ethical

  5. Antitumor activities of a new indolocarbazole substance, NB-506, and establishment of NB-506-resistant cell lines, SBC-3/NB.

    Science.gov (United States)

    Kanzawa, F; Nishio, K; Kubota, N; Saijo, N

    1995-07-01

    The novel anticancer glucosyl derivative of indolo-carbazole (NB-506), an inhibitor of DNA topoisomerase I, exhibited strong in vitro cytotoxicity against various human cancer cell lines. In order to elucidate its cytotoxic mechanisms, we established nine NB-506-resistant sublines with different resistance ratios from human small cell lung cancer cells (SBC-3/P) by stepwise and brief exposure (24 h) to NB-506. Among them, SBC-3/NB#9 was 454 times more resistant to NB-506 than the parent cell line. The SBC-3/NB#9 cells showed cross-resistance only to topoisomerase I inhibitors, such as 11,7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecia and 7-ethyl-10-hydroxy-camptothecin, and not to other anticancer drugs, such as vincristine, vinblastine, Adriamycin, etoposide, and teniposide. These results indicate that the difference on the effect of topoisomerase I was considered to be related to a resistance mechanism. The topoisomerase I activities of nuclear extracts eluted from SBC-3/NB#9 cells was only one-tenth of the parent cell activity. A Western blotting study indicated that this lower activity was due to a lower amount of DNA topoisomerase I. Furthermore, we found correlations between topoisomerase I activity and sensitivity to NB-506 in sublines with different degrees of resistance. Accumulation of 3H-labeled NB-506 by SBC-3/NB#9 cells was only one-fifth of that by the parent cells, whereas intracellular accumulation of 3H-labeled camptothecin by both cell lines did not differ. The reduction of accumulation was specific to NB-506, and this result may explain why the resistance ratio for NB-506 was higher than those for 11,7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin and 7-ethyl-10-hydroxy-camptothecin.

  6. Efficacy of Tailored Physical Activity or Chronic Pain Self-Management Programme on return to work for sick-listed citizens

    DEFF Research Database (Denmark)

    Andersen, Lotte Nygaard; Juul-Kristensen, Birgit; Sørensen, Thomas Lund

    2015-01-01

    . In contrast, no benefit of TPA and CPSMP was evident regarding work ability, kinesiophobia or physical capacity after 3 months of follow-up. CONCLUSIONS: The results suggest that TPA is a promising intervention to facilitate return to work and reduce pain among sick-listed citizens with pain related......OBJECTIVES: The aim was to evaluate the efficacy of 'Tailored Physical Activity' (TPA) and a 'Chronic Pain Self-management Programme' (CPSMP) compared with a reference group (REF) on return to work after 3 months as sick-listed citizens with pain related to the back or the upper body. METHODS......: Using a randomised controlled trial design all participants (n= 141) received health guidance for 1.5 hours and were randomised to TPA, CPSMP or REF. Characteristics of participants were collected from a questionnaire. The primary endpoint was proportion of participants returned to work as registered...

  7. The influence of external environment factors on the activity of higher educational establishments in the Russian Federation

    Directory of Open Access Journals (Sweden)

    Olga Leonidovna Guzakova

    2014-05-01

    Full Text Available The instability of market economy development causes continuous changes in the activity of higher educational establishments. The article deals with the processes, taking place in the system of higher professional education in the Russian Federation in recent decades. On the basis of the analysis of statistical data and normative acts of the Government and Ministry of Education and Science of the Russian Federation, the key global and national trends in higher education are identified: increasing demand for higher education, resulted in its considerable offer (the growth of quantitative indicators is not always accompanied by improvement of higher education quality; reduction in the total number of students due to the demographic situation worsening; transition to a multi-level system of higher education under the Bologna process; change in specialties patterns and directions of training specialists with higher professional education due to the economy structural reforms and labor market needs; aggravation of competition. The tendencies lead to the emergence of demographic, political and economic risks. To reduce negative impact of the external risks to the universities’ activity it is necessary to develop corresponding state educational policy in the sphere of higher education and risk management in universities

  8. A survey of radiation treatment planning peer-review activities in a provincial radiation oncology programme: current practice and future directions

    Science.gov (United States)

    Brundage, Michael; Foxcroft, Sophie; McGowan, Tom; Gutierrez, Eric; Sharpe, Michael; Warde, Padraig

    2013-01-01

    Objectives To describe current patterns of practice of radiation oncology peer review within a provincial cancer system, identifying barriers and facilitators to its use with the ultimate aim of process improvement. Design A survey of radiation oncology programmes at provincial cancer centres. Setting All cancer centres within the province of Ontario, Canada (n=14). These are community-based outpatient facilities overseen by Cancer Care Ontario, the provincial cancer agency. Participants A delegate from each radiation oncology programme filled out a single survey based on input from their multidisciplinary team. Outcome measures Rated importance of peer review; current utilisation; format of the peer-review process; organisation and timing; case attributes; outcomes of the peer-review process and perceived barriers and facilitators to expanding peer-review processes. Results 14 (100%) centres responded. All rated the importance of peer review as at least 8/10 (10=extremely important). Detection of medical error and improvement of planning processes were the highest rated perceived benefits of peer review (each median 9/10). Six centres (43%) reviewed at least 50% of curative cases; four of these centres (29%) conducted peer review in more than 80% of cases treated with curative intent. Fewer than 20% of cases treated with palliative intent were reviewed in most centres. Five centres (36%) reported usually conducting peer review prior to the initiation of treatment. Five centres (36%) recorded the outcomes of peer review on the medical record. Thirteen centres (93%) planned to expand peer-review activities; a critical mass of radiation oncologists was the most important limiting factor (median 6/10). Conclusions Radiation oncology peer-review practices can vary even within a cancer system with provincial oversight. The application of guidelines and standards for peer-review processes, and monitoring of implementation and outcomes, will require effective knowledge

  9. The effectiveness of a physical activity stimulation programme for children with cerebral palsy on social participation, self-perception and quality of life: a randomized controlled trial.

    Science.gov (United States)

    Van Wely, Leontien; Balemans, Astrid Cj; Becher, Jules G; Dallmeijer, Annet J

    2014-10-01

    To determine the effects of a six-month physical activity stimulation programme on social participation, self-perception and quality of life in children with cerebral palsy. Multicentre randomized controlled trial with concealed allocation, blinded assessments and intention-to-treat analysis. Paediatric physiotherapy practices, special schools for children with a disability, and the child's own home. Forty-nine children with spastic cerebral palsy (28 male), aged 7-13 years, able to walk with and without walking aids. The intervention group followed a six-month physical activity stimulation programme involving counselling through motivational interviewing, home-based physiotherapy and four months of fitness training. The control group continued regular paediatric physiotherapy. Outcomes included social participation in domestic life, social participation in recreation and leisure (Life-Habits for Children questionnaire and Children's Assessment of Participation and Enjoyment questionnaire), self-perception (Harter's Self-Perception Profile for Children) and parent-reported quality of life (Cerebral Palsy Quality of Life Questionnaire). Assessments were performed at baseline, at six months (except quality of life) and at twelve months. Intervention resulted in a positive effect on social participation in domestic life at twelve months (mean between-group difference = 0.9, 95% confidence interval (CI) = 0.1 to 1.7 [1-10 scale], P = 0.03), but not at six months. No significant effects were found for social participation in recreation and leisure, self-perception at six months and twelve months or for quality of life at twelve months. The combination of counselling, home-based physiotherapy and fitness training was not effective in improving social participation in recreation and leisure, self-perception or quality of life, but did show a potential for improving social participation in domestic life over the longer term. © The Author(s) 2013.

  10. Olympic Partner Programme

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ The Olympic Partner Programme (TOP) is an international Olympic marketing programme created by the International Olympic Committee (IOC),which includes the Organising Committees of the Games,the National Olympic Committees and the TOP Partners.

  11. Improving the outcome of established therapies for osteoporosis by adding the active D-hormone analog alfacalcidol.

    Science.gov (United States)

    Ringe, J D; Schacht, E

    2007-12-01

    While in other chronic diseases combined treatment regimens are the rule there is a lack of reported experience or study data on combining different specific drugs to treat osteoporosis. Significant differences in the mode of action (MOA) of the substances to be combined may be important for achieving optimal therapeutic results. Recognising that today bisphosphonates are the leading therapy for osteoporosis we suggest that the active D-hormone analog alfacalcidol with its completely different mechanisms of action could be an interesting combination to improve the therapeutic outcome of the pure antiresoptive action of bisphosphonates. Alfacalcidol is activated by the enzyme 25-hydroxylase in the liver for systemic and in osteoblasts for local D-hormone actions. It possesses a unique pattern of pleiotropic effects on, e.g. gut, bone, pararthyroids, muscle and brain. Alfacalcidol is superior to plain vitamin D (cholecalciferol) because the final kidney activation of the latter is regulated by a negative feedback mechanism. In vitamin D replete patients or patients with impaired kidney function no increased D-hormone action at the target tissues can be achieved. Animal studies and several trials in humans with alendronate plus calcitriol or alfacalcidol proved that the combination induced significantly higher increases of bone mineral density (BMD) than the respective mono-therapies. The results of the 2-year AAC-trial from our group indicate that the combination alendronate and alfacalcidol is also superior in terms of falls, fractures and back pain. From the review of the literature and the own new results we conclude that this combined therapeutic regimen is a very promising option for treating established osteoporosis and propose a differentiated use of alfacalcidol alone or the combination with alendronate in different stages and clinical situations of osteoporosis.

  12. LIMK1 activity is required for MTOC localization and spindle bipolarity establishment during meiosis in mouse oocytes

    Institute of Scientific and Technical Information of China (English)

    Liu Xiaoyun; Li Xin; Ma Wei

    2015-01-01

    Aneuploid embryo generally leads to infertility, spontaneous abortion and birth defects, mainly resulting from abnormal chromosome segregation during maternal oocytes meiosis. Chromosome division is conducted by bipolar spindle which formed through an acentrosomal way, dependent on a unique microtubule organizing center ( MTOC) in mammalian oocytes, however, the molecular composition and functional regulation of MTOC is still not fully ex-plored. LIM kinases 1 (LIMK1) is a conserved serine/threonine kinase, a major regulator of actin and microtubule dynamics, involved in microtubule stability and spindle positioning during mitosis. So far little is known about LIMK1 protein expression and its roles in oocytes during meiosis. We reported here the protein expression and sub-cellular distribution of LIMK1 in mouse oocytes during meiosis. Western blot procedure detected high and stable expression of LIMK1 in mouse oocytes from germinal vesicle ( GV) stage to metaphase II ( MII) . In contrast, acti-vated LIMK1 ( phosphorylated at Thr508 , pLIMK1 Thr508 ) was only observed after germinal vesicle breakdown ( GVBD) , and gradually increased with peak levels at metaphase I ( MI) and MII. Immunofluorescence analysis showed that LIMK1 was co-localized with microtubules on the whole spindle structure, while pLIMK1Thr508 was con- centrated with key components of MTOC,pericentrin and -Tubulin, on spindle poles in mouse oocytes. Inhibition of LIMK1 activity by BMS3, a specific ATPase competitive inhibitor, distroyed the formation of bipolar spindle structure, disturbed MTOC integrity and MTOC proteins recruitment to spindle poles. Moreover, LIMK1 inhibition caused chromosome misalignment and meiotic progression arrest at MI stage. Therefore, LIMK1 activity is required for formation and maintenance of bipolar spindle in mouse oocytes,importantly, pLIMK1T508 is MTOC-associated protein,involved in establishment and positioning of MTOC.

  13. Self-reported care activities in a home-based intervention programme for families with multiple problems

    NARCIS (Netherlands)

    Tausendfreund, Tim; Metselaar, Janneke; Conradie, Jelte; de Groot, Maria Helena; Schipaanboord, Nicolien; Knot-Dickscheit, Jana; Grietens, Hans; Knorth, Erik J.

    2015-01-01

    The purpose of this paper is to describe the development and application of the KIPP-list of care activities. The acronym KIPP stands for Knowledge and Insight into Primary Processes. The instrument is intended as a tool for family coaches to systematically report care activities conducted in the Du

  14. Evaluation of a school-based intervention programme to promote physical activity: an application of the theory of planned behavior.

    Science.gov (United States)

    Tsorbatzoudis, Haralambos

    2005-12-01

    The Theory of Planned Behavior provides a useful framework to study attitudes toward participation in physical activity. The objective of the study was to test the effectiveness of an intervention in manipulating the variables of the Theory of Planned Behavior and exercise habits with 366 high school students (M = 14.2 yr., SD = .7; 201 boys and 165 girls). The students were divided into intervention and control groups. A questionnaire to measure components of the theory, and the Baecke Questionnaire of Habitual Activity measuring exercise habits, were administered. The intervention lasted 12 wk. and included posters and lectures promoting participation in physical activity. Analyses showed the intervention was effective in improving attitudes towards physical activity, perceived behavioral control, intention, and self-reported actual behavior, but it was ineffective for improving attitude strength, subjective norms, and role identity. The results provide useful information for physical education teachers interested in promoting students' positive attitudes towards physical activity.

  15. The impact of a bodyweight and physical activity intervention (BeWEL) initiated through a national colorectal cancer screening programme: randomised controlled trial.

    Science.gov (United States)

    Anderson, Annie S; Craigie, Angela M; Caswell, Stephen; Treweek, Shaun; Stead, Martine; Macleod, Maureen; Daly, Fergus; Belch, Jill; Rodger, Jackie; Kirk, Alison; Ludbrook, Anne; Rauchhaus, Petra; Norwood, Patricia; Thompson, Joyce; Wardle, Jane; Steele, Robert J C

    2014-03-07

    To evaluate the impact of a diet and physical activity intervention (BeWEL) on weight change in people with a body mass index >25 weight (kg)/height (m)(2) at increased risk of colorectal cancer and other obesity related comorbidities. Multicentre, parallel group, randomised controlled trial. Four Scottish National Health Service health boards. 329 overweight or obese adults (aged 50 to 74 years) who had undergone colonoscopy after a positive faecal occult blood test result, as part of the national bowel screening programme, and had a diagnosis of adenoma confirmed by histopathology. 163 were randomised to intervention and 166 to control. Participants were randomised to a control group (weight loss booklet only) or 12 month intervention group (three face to face visits with a lifestyle counsellor plus monthly 15 minute telephone calls). A goal of 7% reduction in body weight was set and participants received a personalised energy prescription (2508 kJ (600 kcal) below that required for weight maintenance) and bodyweight scales. Motivational interviewing techniques explored self assessed confidence, ambivalence, and personal values concerning weight. Behavioural strategies included goal setting, identifying intentions of implementation, self monitoring of body weight, and counsellor feedback about reported diet, physical activity, and weight change. The primary outcome was weight change over 12 months. Secondary outcomes included changes in waist circumference, blood pressure, fasting cardiovascular biomarkers, and glucose metabolism variables, physical activity, diet, and alcohol consumption. At 12 months, data on the primary outcome were available for 148 (91%) participants in the intervention group and 157 (95%) in the control group. Mean weight loss was 3.50 kg (SD 4.91) (95% confidence interval 2.70 to 4.30) in the intervention group compared with 0.78 kg (SD 3.77) (0.19 to 1.38) in the control group. The group difference was 2.69 kg (95% confidence interval 1

  16. UNESCO's Ethics Education Programme.

    NARCIS (Netherlands)

    Have, H.A.M.J. ten

    2008-01-01

    Unesco initiated the Ethics Education Programme in 2004 at the request of member states to reinforce and increase the capacities in the area of ethics teaching. The programme is focused on providing detailed information about existing teaching programmes. It also develops and promotes teaching throu

  17. A reappraisal of the virtues of private sector employment programmes

    DEFF Research Database (Denmark)

    Graversen, Brian Krogh; Jensen, Peter

    2010-01-01

    This paper evaluates the employment effects of active labour market programmes for Danish welfare benefit recipients, focusing on private sector employment (PSE) programmes. Using a latent variable model that allows for heterogeneous treatment effects among observationally identical persons, we...

  18. Why some do but most don't. Barriers and enablers to engaging low-income groups in physical activity programmes: a mixed methods study

    Directory of Open Access Journals (Sweden)

    Fox Kenneth R

    2011-06-01

    Full Text Available Abstract Background The beneficial effect of physical activity for the prevention of a range of chronic diseases is widely acknowledged. These chronic conditions are most pronounced in economically disadvantaged groups where physical activity levels are consistently lower, yet this group is particularly difficult to recruit and retain in physical activity programmes. This study examined the perceptions of participants, non-participants, and exercise leaders in a low-income area regarding barriers, motives, and enabling factors for organised physical activity with a view to improving recruitment and retention. Methods A mixed methods research approach was adopted to guide data collection and analysis. A survey, incorporating the Motivation for Physical Activity Measure - Revised (MPAM-R, was used to assess the motivations of 152 physical activity session participants in a highly deprived suburban neighbourhood. The MPAM-R data were analysed using t tests, analyses of variance to estimate age, body mass index, and activity mode differences and Pearson's correlation coefficient to address associations. Semi-structured interviews were also conducted with 33 local residents who did not participate in activity sessions and with 14 activity session leaders. All interviews were audio-taped, transcribed verbatim and analyzed using an inductive thematic approach. Results Participants reported cost, childcare, lack of time and low awareness as barriers to joining activity classes. The need for support, confidence and competence in order to take up activity was widely expressed, particularly among women. Once people are active, high levels of social interaction, interest and enjoyment are associated with improved levels of retention, with different types of physical activity scoring differently on these factors. Conclusions This study suggests that some factors such as cost, the fear of 'walking in alone', accessibility of facilities, and appropriate

  19. Support of Gulf of Mexico Hydrate Research Consortium: Activities of Support Establishment of a Sea Floor Monitoring Station Project

    Energy Technology Data Exchange (ETDEWEB)

    J. Robert Woolsey; Thomas McGee; Carol Lutken

    2008-05-31

    The Gulf of Mexico Hydrates Research Consortium (GOM-HRC) was established in 1999 to assemble leaders in gas hydrates research that shared the need for a way to conduct investigations of gas hydrates and their stability zone in the Gulf of Mexico in situ on a more-or-less continuous basis. The primary objective of the group is to design and emplace a remote monitoring station or sea floor observatory (SFO) on the sea floor in the northern Gulf of Mexico, in an area where gas hydrates are known to be present at, or just below, the sea floor and to discover the configuration and composition of the subsurface pathways or 'plumbing' through which fluids migrate into and out of the hydrate stability zone (HSZ) to the sediment-water interface. Monitoring changes in this zone and linking them to coincident and perhaps consequent events at the seafloor and within the water column is the eventual goal of the Consortium. This mission includes investigations of the physical, chemical and biological components of the gas hydrate stability zone - the sea-floor/sediment-water interface, the near-sea-floor water column, and the shallow subsurface sediments. The eventual goal is to monitor changes in the hydrate stability zone over time. Establishment of the Consortium succeeded in fulfilling the critical need to coordinate activities, avoid redundancies and communicate effectively among those involved in gas hydrates research. Complementary expertise, both scientific and technical, has been assembled to promote innovative methods and construct necessary instrumentation. Following extensive investigation into candidate sites, Mississippi Canyon 118 (MC118) was chosen by consensus of the Consortium at their fall, 2004, meeting as the site most likely to satisfy all criteria established by the group. Much of the preliminary work preceding the establishment of the site - sensor development and testing, geophysical surveys, and laboratory studies - has been reported in

  20. Expert validation of fit-for-purpose guidelines for designing programmes of assessment.

    NARCIS (Netherlands)

    Dijkstra, J.; Galbraith, R.; Hodges, B.D.; McAvoy, P.A.; McCrorie, P.; Southgate, L.J.; Vleuten, C.P.M. van der; Wass, V.; Schuwirth, L.W.

    2012-01-01

    ABSTRACT: BACKGROUND: An assessment programme, a purposeful mix of assessment activities, is necessary to achieve a complete picture of assessee competence. High quality assessment programmes exist, however, design requirements for such programmes are still unclear. We developed guidelines for desig

  1. New and recently finalised activities within the NKS Programmes for Nordic cooperation on nuclear reactor safety and emergency preparedness

    DEFF Research Database (Denmark)

    Andgren, Karin; Andersson, Kasper Grann; Magnússon, Sigurður M.

    2015-01-01

    Over the years, NKS has provided funding for hundreds of research activities in fields comprising reactor safety, decommissioning, nuclear and radiological emergency preparedness, and management of radioactive waste. Advanced technologies and methods developed under the NKS framework have been used...

  2. Influences of establishment and maintenance of territory on reproductive activity in the male dwarf gourami Colisa lalia.

    Science.gov (United States)

    Hayakawa, Youichi; Kobayashi, Makito

    2012-03-01

    We examined the importance of establishment and maintenance of territory on reproductive activity in the male dwarf gourami, Colisa lalia. After three males had been forced to fight for territory (five sets) for three weeks, social status was divided into three classes: the territorially dominant male, which guarded the territory under the floating nest; the second male which remained near the nest and occasionally attacked the dominant male; and the third male which was non-aggressive and remained at a distance from the other two males. Comparing testicular size by gonadosomatic indices (GSI) after three weeks of aggression, GSI of the dominant male (1.19 ± 0.07) was significantly larger than that of the second (0.81 ± 0.15) and the third (0.62 ± 0.08) males, as well as the initial control (not involved in any experiments: 0.85 ± 0.10, n = 5), indicating that the testes of the dominant males enlarge during territory defense. Histological observations of testes revealed that sperm production in the dominant males was more active compared to males of other classes, although spermatogenesis was confirmed in all males examined, suggesting that dominance accelerates sperm production. Social-status dependent development of testes suggests an absence of sperm competition due to the lack of sneaking by subordinate males. Since non-territorial males do not engage in alternative tactics (e.g., sneaking) leading to emission of semen, male C. lalia must obtain and defend territory if they are to increase their reproductive success.

  3. Leishmania donovani activates SREBP2 to modulate macrophage membrane cholesterol and mitochondrial oxidants for establishment of infection.

    Science.gov (United States)

    Mukherjee, Madhuchhanda; Basu Ball, Writoban; Das, Pijush K

    2014-10-01

    Establishment of infection by an intracellular pathogen depends on successful internalization with a concomitant neutralization of host defense machinery. Leishmania donovani, an intramacrophage pathogen, targets host SREBP2, a critical transcription factor, to regulate macrophage plasma membrane cholesterol and mitochondrial reactive oxygen species generation, favoring parasite invasion and persistence. Leishmania infection triggered membrane-raft reorientation-dependent Lyn-PI3K/Akt pathway activation which in turn deactivated GSK3β to stabilize nuclear SREBP2. Moreover, cells perceiving less available intracellular cholesterol due to its sequestration at the plasma membrane resulted in the deregulation of the ER-residing SCAP-SREBP2-Insig circuit thereby assisting increased nuclear translocation of SREBP2. Both increased nuclear transport and stabilization of SREBP2 caused HMGCR-catalyzed cholesterol biosynthesis-mediated plasma membrane cholesterol enrichment leading to decreased membrane-fluidity and plausibly assisting delay in phagosomal acidification. Parasite survival ensuing entry was further ensured by SREBP2-dependent transcriptional up-regulation of UCP2, which suppressed mitochondrial ROS generation, one of the primary microbicidal molecules in macrophages recognized for its efficacy against Leishmania. Functional knock-down of SREBP2 both in vitro and in vivo was associated with reduction in macrophage plasma membrane cholesterol, increased ROS production and lower parasite survival. To our knowledge, this study, for the first time, reveals that Leishmania exploits macrophage cholesterol-dependent SREBP2 circuit to facilitate its entry and survival within the host.

  4. A Statistical Programme Assignment Model

    DEFF Research Database (Denmark)

    Rosholm, Michael; Staghøj, Jonas; Svarer, Michael

    When treatment effects of active labour market programmes are heterogeneous in an observable way  across the population, the allocation of the unemployed into different programmes becomes a particularly  important issue. In this paper, we present a statistical model designed to improve the present...... assignment  mechanism, which is based on the discretionary choice of case workers. This is done in a duration model context, using the timing-of-events framework to identify causal effects. We compare different assignment  mechanisms, and the results suggest that a significant reduction in the average...... duration of unemployment spells may result if a statistical programme assignment model is introduced. We discuss several issues regarding the  plementation of such a system, especially the interplay between the statistical model and  case workers....

  5. The WHO AFRO external quality assessment programme (EQAP: Linking laboratory networks through EQA programmes

    Directory of Open Access Journals (Sweden)

    Debrah I. Boeras

    2016-10-01

    Full Text Available External Quality Assessment (EQA surveys performed by the World Health Organization Regional Office for Africa (WHO AFRO revealed the need for the strengthening of publichealth microbiology laboratories, particularly for testing of epidemic-prone diseases in theAfrican Region. These surveys revealed common issues such as supply chain managementskilled personnel, logistical support and overall lack of quality standards. For sustainableimprovements to health systems as well as global health security, deficiencies identified needto be actively corrected through robust quality assurance programmes and implementation oflaboratory quality management systems.Given all the pathogens of public health importance, an external quality assessment programmewith a focus on vaccine-preventable diseases and emerging and re-emerging dangerouspathogens is important, and should not be stand-alone, but integrated within laboratorynetworks as seen in polio, measles, yellow fever and rubella.In 2015, WHO AFRO collaborated with the US Centers for Disease Control and Preventionthe London School of Hygiene & Tropical Medicine and partners in a series of consultationswith countries and national and regional EQA providers for the development of qualityassurance models to support HIV point-of-care testing and monitoring. These consultationsrevealed similar challenges as seen in the WHO AFRO surveys. WHO AFRO brought forthits experience in implementing quality standards for health programmes, and also openeddiscussions on how lessons learned through such established programmes can be utilised tosupporting and strengthening the introduction of early infant diagnosis of HIV and viralload point-of-care testing.An optimised external quality assessment programme will impact the ability of countries tomeet core capacities, providing improved quality management systems, improving theconfidence of diagnostic network services in Africa, and including capacities to detect eventsof

  6. Concept of the Flemish human biomonitoring programme.

    Science.gov (United States)

    Schoeters, Greet; Den Hond, Elly; Colles, Ann; Loots, Ilse; Morrens, Bert; Keune, Hans; Bruckers, Liesbeth; Nawrot, Tim; Sioen, Isabelle; De Coster, Sam; Van Larebeke, Nicolas; Nelen, Vera; Van de Mieroop, Els; Vrijens, Jan; Croes, Kim; Goeyens, Karen; Baeyens, Willy

    2012-02-01

    Since 2002 a human biomonitoring network has been established in Flanders (Belgium) as part of a programme on environmental health surveillance. The human biomonitoring network should support environmental health policy by identifying priorities for further action. The first cycle of the programme (2002-2006) confirmed the hypotheses that living in areas with different environmental pressure is reflected in different loads of environmental chemicals in the residents. In the second cycle of the programme (2007-2011) the number of environmental chemicals for which human biomonitoring data were obtained was expanded substantially. The goal of the Flemish programme is to use and translate the scientific results into policy actions. Its further orientation in the second cycle to human biomonitoring in hot spots and sensitive age groups or susceptible persons with underlying complications (e.g. persons with diabetes) are linked to these goals. Interaction with stakeholders is embedded in the programme emphasizing transparency of the choices that are made and direct communication. The Flemish human biomonitoring programme is organized centrally with major involvement of research partners from different disciplines which allows engrafting environmental health research on the programme. One of the major focuses is the question whether combinations of pollutants in the general population are associated with biological effects. The objective of this paper is to review and discuss the options that were taken in the human biomonitoring programme in order to achieve its goals.

  7. SUPPORT OF GULF OF MEXICO HYDRATE RESEARCH CONSORTIUM: ACTIVITIES TO SUPPORT ESTABLISHMENT OF A SEA FLOOR MONITORING STATION PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    J. Robert Woolsey; Tom McGee; Carol Lutken; Elizabeth Stidham

    2006-06-01

    The Gulf of Mexico Hydrates Research Consortium (GOM-HRC) was established in 1999 to assemble leaders in gas hydrates research. The Consortium is administered by the Center for Marine Resources and Environmental Technology, CMRET, at the University of Mississippi. The primary objective of the group is to design and emplace a remote monitoring station or sea floor observatory (MS/SFO) on the sea floor in the northern Gulf of Mexico by the year 2007, in an area where gas hydrates are known to be present at, or just below, the sea floor. This mission, although unavoidably delayed by hurricanes and other disturbances, necessitates assembling a station that will monitor physical and chemical parameters of the marine environment, including sea water and sea-floor sediments, on a more-or-less continuous basis over an extended period of time. In 2005, biological monitoring, as a means of assessing environmental health was added to the mission of the MS/SFO. Establishment of the Consortium has succeeded in fulfilling the critical need to coordinate activities, avoid redundancies and communicate effectively among researchers in the arena of gas hydrates research. Complementary expertise, both scientific and technical, has been assembled to promote innovative research methods and construct necessary instrumentation. The observatory has now achieved a microbial dimension in addition to the geophysical and geochemical components it had already included. Initial components of the observatory, a probe that collects pore-fluid samples and another that records sea floor temperatures, were deployed in Mississippi Canyon 118 in May of 2005. Follow-up deployments, planned for fall 2005, had to be postponed due to the catastrophic effects of Hurricane Katrina (and later, Rita) on the Gulf Coast. Every effort was made to locate and retain the services of a suitable vessel and submersibles or Remotely Operated Vehicles (ROVs) following the storms and the loss of the contracted vessel

  8. SUPPORT OF GULF OF MEXICO HYDRATE RESEARCH CONSORTIUM: ACTIVITIES TO SUPPORT ESTABLISHMENT OF A SEA FLOOR MONITORING STATION PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    Paul Higley; J. Robert Woolsey; Ralph Goodman; Vernon Asper; Boris Mizaikoff; Angela Davis; Bob A. Hardage; Jeffrey Chanton; Rudy Rogers

    2006-03-01

    The Gulf of Mexico Hydrates Research Consortium was established in 1999 to assemble leaders in gas hydrates research. The group is administered by the Center for Marine Resources and Environmental Technology, CMRET, at the University of Mississippi. The primary objective of the group is to design and emplace a remote monitoring station or sea floor observatory on the sea floor in the northern Gulf of Mexico by the year 2005, in an area where gas hydrates are known to be present at, or just below, the sea floor. This mission necessitates assembling a station that will monitor physical and chemical parameters of the sea water and sea floor sediments on a more-or-less continuous basis over an extended period of time. Development of the station has always included the possibility of expanding its capabilities to include biological monitoring, as a means of assessing environmental health. This possibility has recently received increased attention and the group of researchers working on the station has expanded to include several microbial biologists. Establishment of the Consortium has succeeded in fulfilling the critical need to coordinate activities, avoid redundancies and communicate effectively among researchers in this relatively new research arena. Complementary expertise, both scientific and technical, has been assembled to promote innovative research methods and construct necessary instrumentation. Initial components of the observatory, a probe that collects pore-fluid samples and another that records sea floor temperatures, were deployed in Mississippi Canyon 118 in May of 2005. Follow-up deployments are planned for fall 2005 and center about the use of the vessel M/V Ocean Quest and its two manned submersibles. The subs will be used to effect bottom surveys, emplace sensors and sea floor experiments and make connections between sensor data loggers and the integrated data power unit (IDP). Station/observatory completion is anticipated for 2007 following the

  9. Uptake of Space Technologies - An Educational Programme

    Science.gov (United States)

    Bacai, Hina; Zolotikova, Svetlana; Young, Mandy; Cowsill, Rhys; Wells, Alan; Monks, Paul; Archibald, Alexandra; Smith, Teresa

    2013-04-01

    Earth Observation data and remote sensing technologies have been maturing into useful tools that can be utilised by local authorities and businesses to aid in activates such as monitoring climate change trends and managing agricultural land and water uses. The European Earth observation programme Copernicus, previously known as GMES (Global Monitoring for Environment and Security), provides the means to collect and process multi-source EO and environmental data that supports policy developments at the European level. At the regional and local level, the Copernicus programme has been initiated through Regional Contact Office (RCO), which provide knowledge, training, and access to expertise both locally and at a European level through the network of RCOs established across Europe in the DORIS_Net (Downstream Observatory organised by Regions active In Space - Network) project (Grant Agreement No. 262789 Coordination and support action (Coordinating) FP7 SPA.2010.1.1-07 "Fostering downstream activities and links with regions"). In the East Midlands UK RCO, educational and training workshops and modules have been organised to highlight the wider range of tools and application available to businesses and local authorities in the region. Engagement with businesses and LRA highlighted the need to have a tiered system of training to build awareness prior to investigating innovative solutions and space technology uses for societal benefits. In this paper we outline education and training programmes which have been developed at G-STEP (GMES - Science and Technology Education Partnership), University of Leicester, UK to open up the Copernicus programme through the Regional Contact Office to downstream users such as local businesses and LRAs. Innovative methods to introduce the operational uses of Space technologies in real cases through e-learning modules and web-based tools will be described and examples of good practice for educational training in these sectors will be

  10. Computational Fluid Dynamics (CFD) Technology Programme 1995- 1999

    Energy Technology Data Exchange (ETDEWEB)

    Haekkinen, R.J.; Hirsch, C.; Krause, E.; Kytoemaa, H.K. [eds.

    1997-12-31

    The report is a mid-term evaluation of the Computational Fluid Dynamics (CFD) Technology Programme started by Technology Development Centre Finland (TEKES) in 1995 as a five-year initiative to be concluded in 1999. The main goal of the programme is to increase the know-how and application of CFD in Finnish industry, to coordinate and thus provide a better basis for co-operation between national CFD activities and encouraging research laboratories and industry to establish co-operation with the international CFD community. The projects of the programme focus on the following areas: (1) studies of modeling the physics and dynamics of the behaviour of fluid material, (2) expressing the physical models in a numerical mode and developing a computer codes, (3) evaluating and testing current physical models and developing new ones, (4) developing new numerical algorithms, solvers, and pre- and post-processing software, and (5) applying the new computational tools to problems relevant to their ultimate industrial use. The report consists of two sections. The first considers issues concerning the whole programme and the second reviews each project

  11. Impact of a school-based intervention on nutritional education and physical activity in primary public schools in Chile (KIND) programme study protocol: cluster randomised controlled trial.

    Science.gov (United States)

    Bustos, Nelly; Olivares, Sonia; Leyton, Bárbara; Cano, Marcelo; Albala, Cecilia

    2016-12-03

    Chile has suffered a fast increase in childhood obesity in the last 10 years. As a result, several school programmes have been implemented, however the effectiveness of these needs to be evaluated to identify and prioritize strategies to curve this trend. Cluster randomized controlled trial. Twelve primary public schools chosen at random over three regions of the country will take part in this study. The sample size consisted of a total of 1,655 children. For each region one school will be selected for each of the three nutritional intervention modes and one school will be selected as the control group. The intervention modes consist of the following: Healthy Kiosk and nutritional education (KSEAN); Optimized physical activity (AFSO); Healthy Kiosk and nutritional education (KSEAN) + optimized physical activity (AFSO); Control group. The effectiveness of each intervention will be evaluated by determining the nutritional condition of each child by measuring percentage of body fat, BMI and the z-score of the BMI. This study will also identify the eating behaviours, nutritional knowledge and fitness of each child, along with the effective time of moderate activity during physical education classes. A protocol to evaluate the effectiveness of a school based intervention to control and/or reduce the rates of childhood obesity for children between 6 and 10 years of age was developed. The protocol was developed in line with the Declaration of Helsinski, the Nüremberg Code and the University of Chile Guidelines for ethical committees, and was approved by the INTA, Universidad de Chile ethical committee on Wednesday 12 March 2014. There is consensus among researchers and health and education personnel that schools are a favourable environment for actions to prevent and/or control childhood obesity. However a lack of evidence on the effectiveness of interventions to date has led some to question the wisdom of allocating resources to programmes. This is the first study

  12. Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing

    DEFF Research Database (Denmark)

    Bousquet, J; Farrell, J; Crooks, G;

    2016-01-01

    Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS ...

  13. Implementation of a metrology programme to provide traceability for radionuclides activity measurements in the CNEN Radiopharmaceuticals Producers Centers

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Erica A.L. de; Braghirolli, Ana M.S.; Tauhata, Luiz; Gomes, Regio S.; Silva, Carlos J., E-mail: erica@ien.gov.br [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Delgado, Jose U.; Oliveira, Antonio E.; Iwahara, Akira, E-mail: ealima@ird.gov.br [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2013-07-01

    The commercialization and use of radiopharmaceuticals in Brazil are regulated by Agencia Nacional de Vigilancia Sanitaria (ANVISA) which require Good Manufacturing Practices (GMP) certification for Radiopharmaceuticals Producer Centers. Quality Assurance Program should implement the GMP standards to ensure radiopharmaceuticals have requirements quality to proving its efficiency. Several aspects should be controlled within the Quality Assurance Programs, and one of them is the traceability of the Radionuclides Activity Measurement in radiopharmaceuticals doses. The quality assurance of activity measurements is fundamental to maintain both the efficiency of the nuclear medicine procedures and patient and exposed occupationally individuals safety. The radiation doses received by patients, during the nuclear medicine procedures, is estimated according to administered radiopharmaceuticals quantity. Therefore it is very important either the activity measurements performed in radiopharmaceuticals producer centers (RPC) as the measurements performed in nuclear medicine services are traceable to national standards. This paper aims to present an implementation program to provide traceability to radionuclides activity measurements performed in the dose calibrators(well type ionization chambers) used in Radiopharmaceuticals Producer Center placed in different states in Brazil. The proposed program is based on the principles of GM Pand ISO 17025 standards. According to dose calibrator performance, the RPC will be able to provide consistent, safe and effective radioactivity measurement to the nuclear medicine services. (author)

  14. Support of Gulf of Mexico Hydrate Research Consortium: Activities of Support Establishment of a Sea Floor Monitoring Station Project

    Energy Technology Data Exchange (ETDEWEB)

    J. Robert Woolsey; Thomas McGee; Carol Lutken

    2008-05-31

    The Gulf of Mexico Hydrates Research Consortium (GOM-HRC) was established in 1999 to assemble leaders in gas hydrates research that shared the need for a way to conduct investigations of gas hydrates and their stability zone in the Gulf of Mexico in situ on a more-or-less continuous basis. The primary objective of the group is to design and emplace a remote monitoring station or sea floor observatory (SFO) on the sea floor in the northern Gulf of Mexico, in an area where gas hydrates are known to be present at, or just below, the sea floor and to discover the configuration and composition of the subsurface pathways or 'plumbing' through which fluids migrate into and out of the hydrate stability zone (HSZ) to the sediment-water interface. Monitoring changes in this zone and linking them to coincident and perhaps consequent events at the seafloor and within the water column is the eventual goal of the Consortium. This mission includes investigations of the physical, chemical and biological components of the gas hydrate stability zone - the sea-floor/sediment-water interface, the near-sea-floor water column, and the shallow subsurface sediments. The eventual goal is to monitor changes in the hydrate stability zone over time. Establishment of the Consortium succeeded in fulfilling the critical need to coordinate activities, avoid redundancies and communicate effectively among those involved in gas hydrates research. Complementary expertise, both scientific and technical, has been assembled to promote innovative methods and construct necessary instrumentation. Following extensive investigation into candidate sites, Mississippi Canyon 118 (MC118) was chosen by consensus of the Consortium at their fall, 2004, meeting as the site most likely to satisfy all criteria established by the group. Much of the preliminary work preceding the establishment of the site - sensor development and testing, geophysical surveys, and laboratory studies - has been reported in

  15. The HADES RV Programme with HARPS-N@TNG. III. Flux-flux and activity-rotation relationships of early-M dwarfs

    CERN Document Server

    Maldonado, J; Stelzer, B; Biazzo, K; Lanza, A F; Maggio, A; Micela, G; González-Álvarez, E; Affer, L; Claudi, R U; Cosentino, R; Damasso, M; Desidera, S; Hernández, J I González; Gratton, R; Leto, G; Messina, S; Molinari, E; Pagano, I; Perger, M; Piotto, G; Rebolo, R; Ribas, I; Sozzetti, A; Mascareño, A Suárez; Sanchez, R Zanmar

    2016-01-01

    (Abridged) Understanding stellar activity in M dwarfs is crucial for the physics of stellar atmospheres as well as for ongoing radial velocity exoplanet programmes. Despite the increasing interest in M dwarfs, our knowledge of the chromospheres of these stars is far from being complete. We aim to test whether the relations between activity, rotation, and stellar parameters and flux-flux relationships also hold for early-M dwarfs on the main-sequence. We analyse in an homogeneous and coherent way a well defined sample of 71 late-K/early-M dwarfs that are currently being observed in the framework of the HArps-n red Dwarf Exoplanet Survey (HADES). Rotational velocities are derived using the cross-correlation technique while emission flux excesses in the Ca II H & K and Balmer lines from Halpha up to Hepsilon are obtained by using the spectral subtraction technique. The relationships between the emission excesses and the stellar parameters are studied. Relations between pairs of fluxes of different chromosphe...

  16. Contribution of space platforms to a ground and airborne remote-sensing programme over active Italian volcanoes

    Science.gov (United States)

    Cassinis, R.; Lechi, G. M.; Tonelli, A. M.

    1974-01-01

    ERTS-1 imagery of the volcanic areas of southern Italy was used primarily for the evaluation of space platform capabilties in the domains of regional geology, soil and rock-type classification and, more generally, to study the environment of active volcanoes. The test sites were selected and equipped primarily to monitor thermal emission, but ground truth data was also collected in other domains (reflectance of rocks, soils and vegetation). The test areas were overflown with a two channel thermal scanner, while a thermo camera was used on the ground to monitor the hot spots. The primary goal of this survey was to plot the changes in thermal emission with time in the framework of a research program for the surveillance of active volcanoes. However, another task was an evaluation of emissivity changes by comparing the outputs of the two thermal channels. These results were compared with the reflectance changes observed on multispectral ERTS-1 imagery.

  17. Inhibition of the NOTCH pathway using γ-secretase inhibitor RO4929097 has limited antitumor activity in established glial tumors.

    Science.gov (United States)

    Dantas-Barbosa, Carmela; Bergthold, Guillaume; Daudigeos-Dubus, Estelle; Blockus, Heike; Boylan, John F; Ferreira, Celine; Puget, Stephanie; Abely, Michel; Vassal, Gilles; Grill, Jacques; Geoerger, Birgit

    2015-03-01

    Notch signaling is altered in many cancers. Our previous findings in primary pediatric ependymoma support a role for NOTCH in glial oncogenesis. The present study evaluates the γ-secretase inhibitor RO4929097 in glial tumor models. The expression of Notch pathway genes was evaluated using real-time RT-PCR in 21 ependymoma and glioma models. NOTCH1 mutations were analyzed by DNA sequencing. RO4929097 activity was evaluated in vitro and in vivo, as a single agent and in combination, in glioma and ependymoma models. Notch pathway genes are overexpressed in ependymomas and gliomas along with FBXW7 downregulation. NOTCH1 mutations in the TAD domain were observed in 20% (2/10) of ependymoma primary cultures. Blocking the Notch pathway with the γ-secretase inhibitor RO4929097 reduced cell density and viability in ependymoma short-term cultures. When combined with chemotherapeutic agents, RO4929097 enhanced temozolomide effects in ependymoma short-term cultures and potentiated the cytotoxicity of etoposide, cisplatinum, and temozolomide in glioma cells. RO4929097, in combined treatment with mTOR inhibition, potentiated cytotoxicity in vitro, but did not enhance antitumor effects in vivo. In contrast, RO4929097 enhanced irradiation effects in glioma and ependymoma xenografts and showed tumor growth inhibition in advanced-stage IGRG121 glioblastoma xenografts. RO4929097-mediated effects were independent of NOTCH1 mutation status or expression levels, but associated with low IL-6 levels. In established glial tumor models, NOTCH inhibition had limited effects as a single agent, but enhanced efficacy when combined with DNA-interfering agents. These preclinical data need to be considered for further clinical development of NOTCH inhibitors in glial tumors.

  18. An infant oral health programme in Goiânia-GO, Brazil: results after 3 years of establishment Um programa de Saúde Bucal para bebês em Goiânia-GO: resultados após 3 anos

    Directory of Open Access Journals (Sweden)

    Marina Batista Borges Pereira

    2004-03-01

    Full Text Available The objective of this study was to describe the outcomes of an infant oral health programme 3 years after implementation, a programme focused on health education for parents and caries prevention methods for children in a baby clinic. A retrospective cohort study was carried out. The setting was the Infant Oral Health Programme developed at the baby clinic of the State Department of Health, Goiânia-GO, Brazil. The sample comprised 100 children who entered the programme from birth to 12 months and were followed for 2 to 3 years. Variables investigated were caries experience, caries risk, and children's behaviour in the dental clinic. The number of children with caries experience was 1 at the initial visit and 8 after the follow-up. There was a dramatic decrease in the number of children in the high risk group, from 51% at the initial visit to only 1% after 2 to 3 years. Children's behaviour in the dental clinic was according to their psychological development. It was concluded that the Infant Oral Health Programme in Goiânia showed positive outcomes after 3 years of establishment. Further investigations should evaluate the cost-benefit, as well as the effectiveness of the procedures used in the programme.O objetivo do presente estudo foi descrever os resultados após 3 anos de implantação de um programa odontológico para bebês, com ênfase na educação dos pais e em métodos de prevenção para as crianças. Foi realizado um estudo de coorte retrospectivo utilizando-se dados do Programa de Saúde Bucal para Bebês desenvolvido na Secretaria Estadual de Saúde de Goiânia-GO, Brasil. A amostra foi constituída de 100 crianças que freqüentaram o programa desde o nascimento até os 12 meses de idade e que foram acompanhadas durante 2 a 3 anos. As variáveis investigadas foram a experiência de cárie, o risco de cárie e o comportamento das crianças na clínica. O número de crianças com experiência de cárie foi uma na visita inicial e

  19. Photovoltaic programme - edition 2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    This publication issued by the Swiss Federal Office of Energy's Photovoltaics (PV) Programme presents an overview (in English) of activities and projects in the photovoltaics research and pilot and demonstration area in Switzerland. Progress in the area of future solar cell technologies, modules and building integration, system technologies, planning and operating aids is summarised. Also, PV for applications in developing countries, thermo-photovoltaics and international co-operation are commented on. In the area of pilot and demonstration projects, component development, PV integration in sloping roofs, on flat roofs and noise barriers as well as further PV plant are looked at. Also, measurement campaigns, studies, statistics and further PV-related topics are summarised. This volume also presents the abstracts of reports made by the project managers of 73 research and pilot and demonstration projects in these areas for 2002.

  20. Positive affect as coercive strategy: conditionality, activation and the role of psychology in UK government workfare programmes.

    Science.gov (United States)

    Friedli, Lynne; Stearn, Robert

    2015-06-01

    Eligibility for social security benefits in many advanced economies is dependent on unemployed and underemployed people carrying out an expanding range of job search, training and work preparation activities, as well as mandatory unpaid labour (workfare). Increasingly, these activities include interventions intended to modify attitudes, beliefs and personality, notably through the imposition of positive affect. Labour on the self in order to achieve characteristics said to increase employability is now widely promoted. This work and the discourse on it are central to the experience of many claimants and contribute to the view that unemployment is evidence of both personal failure and psychological deficit. The use of psychology in the delivery of workfare functions to erase the experience and effects of social and economic inequalities, to construct a psychological ideal that links unemployment to psychological deficit, and so to authorise the extension of state-and state-contracted-surveillance to psychological characteristics. This paper describes the coercive and punitive nature of many psycho-policy interventions and considers the implications of psycho-policy for the disadvantaged and excluded populations who are its primary targets. We draw on personal testimonies of people experiencing workfare, policy analysis and social media records of campaigns opposed to workfare in order to explore the extent of psycho-compulsion in workfare. This is an area that has received little attention in the academic literature but that raises issues of ethics and professional accountability and challenges the field of medical humanities to reflect more critically on its relationship to psychology.

  1. SUPPORT OF GULF OF MEXICO HYDRATE RESEARCH CONSORTIUM: ACTIVITIES TO SUPPORT ESTABLISHMENT OF A SEA FLOOR MONITORING STATION PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    Paul Higley; J. Robert Woolsey; Ralph Goodman; Vernon Asper; Boris Mizaikoff; Angela Davis

    2005-11-01

    A Consortium, designed to assemble leaders in gas hydrates research, has been established at the University of Mississippi's Center for Marine Resources and Environmental Technology, CMRET. The primary objective of the group is to design and emplace a remote monitoring station on the sea floor in the northern Gulf of Mexico by the year 2005, in an area where gas hydrates are known to be present at, or just below, the sea floor. This mission necessitates assembling a station that will monitor physical and chemical parameters of the sea water and sea floor sediments on a more-or-less continuous basis over an extended period of time. Development of the station allows for the possibility of expanding its capabilities to include biological monitoring, as a means of assessing environmental health. Establishment of the Consortium has succeeded in fulfilling the critical need to coordinate activities, avoid redundancies and communicate effectively among researchers in this relatively new research arena. Complementary expertise, both scientific and technical, has been assembled to promote innovative research methods and construct necessary instrumentation. Noteworthy achievements one year into the extended life of this cooperative agreement include: (1) Progress on the vertical line array (VLA) of sensors: (1a) Repair attempts of the VLA cable damaged in the October >1000m water depth deployment failed; a new design has been tested successfully. (1b) The acoustic modem damaged in the October deployment was repaired successfully. (1c) Additional acoustic modems with greater depth rating and the appropriate surface communications units have been purchased. (1d) The VLA computer system is being modified for real time communications to the surface vessel using radio telemetry and fiber optic cable. (1e) Positioning sensors--including compass and tilt sensors--were completed and tested. (1f) One of the VLAs has been redesigned to collect near sea floor geochemical data. (2

  2. Support of Gulf of Mexico Hydrate Research Consortium: Activities to Support Establishment of a Sea Floor Monitoring Station Project

    Energy Technology Data Exchange (ETDEWEB)

    Carol Lutken

    2006-09-30

    The Gulf of Mexico Hydrates Research Consortium (GOM-HRC) was established in 1999 to assemble leaders in gas hydrates research. The Consortium is administered by the Center for Marine Resources and Environmental Technology, CMRET, at the University of Mississippi. The primary objective of the group is to design and emplace a remote monitoring station or sea floor observatory (MS/SFO) on the sea floor in the northern Gulf of Mexico by the year 2007, in an area where gas hydrates are known to be present at, or just below, the sea floor. This mission, although unavoidably delayed by hurricanes and other disturbances, necessitates assembling a station that will monitor physical and chemical parameters of the marine environment, including sea water and sea-floor sediments, on a more-or-less continuous basis over an extended period of time. In 2005, biological monitoring, as a means of assessing environmental health, was added to the mission of the MS/SFO. Establishment of the Consortium has succeeded in fulfilling the critical need to coordinate activities, avoid redundancies and communicate effectively among researchers in the arena of gas hydrates research. Complementary expertise, both scientific and technical, has been assembled to promote innovative research methods and construct necessary instrumentation. The observatory has now achieved a microbial dimension in addition to the geophysical, geological, and geochemical components it had already included. Initial components of the observatory, a probe that collects pore-fluid samples and another that records sea floor temperatures, were deployed in Mississippi Canyon 118 in May of 2005. Follow-up deployments, planned for fall 2005, had to be postponed due to the catastrophic effects of Hurricane Katrina (and later, Rita) on the Gulf Coast. Station/observatory completion, anticipated for 2007, will likely be delayed by at least one year. The CMRET has conducted several research cruises during this reporting period

  3. Support of Gulf of Mexico Hydrate Research Consortium: Activities to Support Establishment of a Sea Floor Monitoring Station Project

    Energy Technology Data Exchange (ETDEWEB)

    J. Robert Woolsey; Thomas M. McGee; Carol Blanton Lutken; Elizabeth Stidham

    2007-03-31

    The Gulf of Mexico Hydrates Research Consortium (GOM-HRC) was established in 1999 to assemble leaders in gas hydrates research. The Consortium is administered by the Center for Marine Resources and Environmental Technology, CMRET, at the University of Mississippi. The primary objective of the group is to design and emplace a remote monitoring station or sea floor observatory (MS/SFO) on the sea floor in the northern Gulf of Mexico by the year 2007, in an area where gas hydrates are known to be present at, or just below, the sea floor. This mission, although unavoidably delayed by hurricanes and other disturbances, necessitates assembling a station that will monitor physical and chemical parameters of the marine environment, including sea water and sea-floor sediments, on a more-or-less continuous basis over an extended period of time. In 2005, biological monitoring, as a means of assessing environmental health, was added to the mission of the MS/SFO. Establishment of the Consortium has succeeded in fulfilling the critical need to coordinate activities, avoid redundancies and communicate effectively among researchers in the arena of gas hydrates research. Complementary expertise, both scientific and technical, has been assembled to promote innovative research methods and construct necessary instrumentation. The observatory has now achieved a microbial dimension in addition to the geophysical, geological, and geochemical components it had already included. Initial components of the observatory, a probe that collects pore-fluid samples and another that records sea floor temperatures, were deployed in Mississippi Canyon 118 (MC118) in May of 2005. Follow-up deployments, planned for fall 2005, had to be postponed due to the catastrophic effects of Hurricane Katrina (and later, Rita) on the Gulf Coast. Station/observatory completion, anticipated for 2007, will likely be delayed by at least one year. These delays caused scheduling and deployments difficulties but many

  4. SUPPORT OF GULF OF MEXICO HYDRATE RESEARCH CONSORTIUM: ACTIVITIES TO SUPPORT ESTABLISHMENT OF A SEA FLOOR MONITORING STATION PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    Paul Higley; J. Robert Woolsey; Ralph Goodman; Vernon Asper; Boris Mizaikoff; Angela Davis; Bob A. Hardage; Jeffrey Chanton; Rudy Rogers

    2006-05-18

    The Gulf of Mexico Hydrates Research Consortium (GOM-HRC) was established in 1999 to assemble leaders in gas hydrates research. The primary objective of the group has been to design and emplace a remote monitoring station or sea floor observatory (MS/SFO) on the sea floor in the northern Gulf of Mexico by the year 2005, in an area where gas hydrates are known to be present at, or just below, the sea floor. This mission, although unavoidably delayed by hurricanes and other disturbances, necessitates assembling a station that will monitor physical and chemical parameters of the sea water and sea floor sediments on a more-or-less continuous basis over an extended period of time. Development of the station has always included the possibility of expanding its capabilities to include biological monitoring, as a means of assessing environmental health. This possibility has recently achieved reality via the National Institute for Undersea Science and Technology's (NIUST) solicitation for proposals for research to be conducted at the MS/SFO. Establishment of the Consortium has succeeded in fulfilling the critical need to coordinate activities, avoid redundancies and communicate effectively among researchers in the arena of gas hydrates research. Complementary expertise, both scientific and technical, has been assembled to promote innovative research methods and construct necessary instrumentation. The observatory has achieved a microbial dimension in addition to the geophysical and geochemical components it had already included. Initial components of the observatory, a probe that collects pore-fluid samples and another that records sea floor temperatures, were deployed in Mississippi Canyon 118 in May of 2005. Follow-up deployments, planned for fall 2005, have had to be postponed and the use of the vessel M/V Ocean Quest and its two manned submersibles sacrificed due to the catastrophic effects of Hurricane Katrina (and later, Rita) on the Gulf Coast. Every effort is

  5. Drosophila Grainyhead specifies late programmes of neural proliferation by regulating the mitotic activity and Hox-dependent apoptosis of neuroblasts.

    Science.gov (United States)

    Cenci, Caterina; Gould, Alex P

    2005-09-01

    The Drosophila central nervous system is generated by stem-cell-like progenitors called neuroblasts. Early in development, neuroblasts switch through a temporal series of transcription factors modulating neuronal fate according to the time of birth. At later stages, it is known that neuroblasts switch on expression of Grainyhead (Grh) and maintain it through many subsequent divisions. We report that the function of this conserved transcription factor is to specify the regionalised patterns of neurogenesis that are characteristic of postembryonic stages. In the thorax, Grh prolongs neural proliferation by maintaining a mitotically active neuroblast. In the abdomen, Grh terminates neural proliferation by regulating the competence of neuroblasts to undergo apoptosis in response to Abdominal-A expression. This study shows how a factor specific to late-stage neural progenitors can regulate the time at which neural proliferation stops, and identifies mechanisms linking it to the Hox axial patterning system.

  6. Antimicrobial stewardship in Scotland: impact of a national programme

    Directory of Open Access Journals (Sweden)

    Nathwani Dilip

    2012-02-01

    Full Text Available Abstract Backgound The Scottish Antimicrobial Prescribing Group (SAPG was established by the Scottish Government in 2008 to lead the first national initiative to actively address antimicrobial stewardship. Healthcare associated infection (HAI is a priority in Scotland and the work of SAPG contributes to the national HAI Delivery Plan. SAPG's early work has focused on restricting the use of antibiotics associated with a high risk of Clostridium difficile infection (CDI and development of national prescribing indicators to support reduction of CDI. Findings Scottish Antimicrobial Prescribing Group has developed prescribing indicators for hospital and primary care, which are measured and reported in all 14 NHS board areas. Improvement in compliance with the indicators has been demonstrated with resultant reductions in CDI rates and no adverse effect on mortality or antimicrobial resistance patterns. Conclusions The establishment of a Scottish national antimicrobial stewardship programme has made a significant contribution to the HAI agenda, particularly in relation to CDI. The programme is supported by local antimicrobial teams, a national framework for education, surveillance of antimicrobial use and resistance and sharing of data for improvement. Antimicrobial stewardship has been integrated with other national programmes on patient safety and quality improvement.

  7. Evaluating an in-home multicomponent cognitive behavioural programme to manage concerns about falls and associated activity avoidance in frail community-dwelling older people: Design of a randomised control trial [NCT01358032

    Directory of Open Access Journals (Sweden)

    van Rossum Erik

    2011-09-01

    Full Text Available Abstract Background Concerns about falls are frequently reported by older people. These concerns can have serious consequences such as an increased risk of falls and the subsequent avoidance of activities. Previous studies have shown the effectiveness of a multicomponent group programme to reduce concerns about falls. However, owing to health problems older people may not be able to attend a group programme. Therefore, we adapted the group approach to an individual in-home programme. Methods/Design A two-group randomised controlled trial has been developed to evaluate the in-home multicomponent cognitive behavioural programme to manage concerns about falls and associated activity avoidance in frail older people living in the community. Persons were eligible for study if they were 70 years of age or over, perceived their general health as fair or poor, had at least some concerns about falls and associated avoidance of activity. After screening for eligibility in a random sample of older people, eligible persons received a baseline assessment and were subsequently allocated to the intervention or control group. Persons assigned to the intervention group were invited to participate in the programme, while those assigned to the control group received care as usual. The programme consists of seven sessions, comprising three home visits and four telephone contacts. The sessions are aimed at instilling adaptive and realistic views about falls, as well as increasing activity and safe behaviour. An effect evaluation, a process evaluation and an economic evaluation are conducted. Follow-up measurements for the effect evaluation are carried out 5 and 12 months after the baseline measurement. The primary outcomes of the effect evaluation are concerns about falls and avoidance of activity as a result of these concerns. Other outcomes are disability and falls. The process evaluation measures: the population characteristics reached; protocol adherence by

  8. An After-School, high-intensity, interval physical activity programme improves health-related fitness in children

    Directory of Open Access Journals (Sweden)

    Sergio Reloba Martínez

    Full Text Available Abstract Health problems related to a low level of physical activity (PA in children and adolescents have prompted research into extracurricular PA programs. This study was designed to determine the effects of two different levels of PA on the health-related fitness of school children. Ninety-four girls and boys (7-9 years were randomly assigned to a control group (CG or intervention group (IG. Over a 12 week study period, children in the CG participated in a similar PA program to that of a standard school physical education program while those in the IG completed a high intensity interval training (HIIT program. Both programs involved two 40 minute extracurricular sessions per week. Our findings indicate that the HIIT intervention improved motor capacity (speed/agility, Vpeak, VO2 max and excess post-exercise oxygen consumption (EPOC (p < 0.05 along with the musculoskeletal capacity of the lower trunk (mean propulsive velocity and standing long jump, p < 0.05. The PA program had no effect on anthropometric variables or hand-grip strength. The data indicate that a 12 week strength training program using workloads adapted to children may significantly improve several markers of health and physical fitness compared to a standard school PA program.

  9. SUPPORT OF GULF OF MEXICO HYDRATE RESEARCH CONSORTIUM: ACTIVITIES TO SUPPORT ESTABLISHMENT OF A SEA FLOOR MONITORING STATION PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    Paul Higley; J. Robert Woolsey; Ralph Goodman; Vernon Asper; Boris Mizaikoff; Angela Davis

    2005-09-01

    A Consortium, designed to assemble leaders in gas hydrates research, has been established at the University of Mississippi's Center for Marine Resources and Environmental Technology, CMRET. The primary objective of the group is to design and emplace a remote monitoring station on the sea floor in the northern Gulf of Mexico by the year 2005, in an area where gas hydrates are known to be present at, or just below, the sea floor. This mission necessitates assembling a station that will monitor physical and chemical parameters of the sea water and sea floor sediments on a more-or-less continuous basis over an extended period of time. Development of the station allows for the possibility of expanding its capabilities to include biological monitoring, as a means of assessing environmental health. Establishment of the Consortium has succeeded in fulfilling the critical need to coordinate activities, avoid redundancies and communicate effectively among researchers in this relatively new research arena. Complementary expertise, both scientific and technical, has been assembled to promote innovative research methods and construct necessary instrumentation. Noteworthy achievements six months into the extended life of this cooperative agreement include: (1) Progress on the vertical line array (VLA) of sensors: Analysis and repair attempts of the VLA used in the deep water deployment during October 2003 have been completed; Definition of an interface protocol for the VLA DATS to the SFO has been established; Design modifications to allow integration of the VLA to the SFO have been made; Experience gained in the deployments of the first VLA is being applied to the design of the next VLAs; One of the two planned new VLAs being modified to serve as an Oceanographic Line Array (OLA). (2) Progress on the Sea Floor Probe: The decision to replace the Sea Floor Probe technology with the borehole emplacement of a geophysical array was reversed due to the 1300m water depth at the

  10. Effects of physical activity programmes in the workplace (PAPW) on the perception and intensity of musculoskeletal pain experienced by garment workers.

    Science.gov (United States)

    Pereira, Cynara Cristina Domingues Alves; López, Ramón Fabian Alonso; Vilarta, Roberto

    2013-01-01

    The physical activity programmes in the workplace (PAPW) are applied to minimize the prevalence, incidence and intensity of pain. This study evaluated the perception of pain and quantifies its intensity among garment workers before and after performing a PAPW. We included 61 workers of a clothing company, who were classified randomly into experimental group (n = 44) 28.7 ± 8.8 years old and a control group (n = 17) 27.8 ± 7.4 years (20-43 years). The Trigger Points test questionnaire was used to assess pain perception and quantify its intensity. The PAPW was conducted in 15-minute sessions per day, consisting of stretching exercises (40%), muscular endurance (40%), self-massage relaxation and massage techniques (10%), and group dynamics (10%). The garment workers who participated in the PAPW showed a significant reduction of pain felt in the neck and wrists, and also a reduction in pain intensity in shoulders, arms, fingers and wrists that are most often strained during sewing. Our findings suggest that PAPW that target muscle groups that are more tense in sewing tasks, may be considered by companies for supporting adaptation to the work environment and improving health by reducing muscle and joint pain.

  11. A Randomised Control Trial of the Impact of a Computer-Based Activity Programme upon the Fitness of Children with Autism

    Directory of Open Access Journals (Sweden)

    Kathleen Dickinson

    2014-01-01

    Full Text Available The poor levels of fitness in children with autism are prompting concern for the children’s future health. This study looked to assess if a computer-based activity programme could improve fitness levels (as reflected in cardiopulmonary function of these children, and achieve a reduction in their body mass index. In a randomised controlled trial, 50 children with autism (of which 33 were under the age of 11 years and 39 were boys were allocated to an intervention group which encouraged them to use the Nintendo Wii and the software package “Mario and Sonics at the Olympics” in addition to their routine physical education classes. 50 children with autism (34 under the age of 11 years and 40 being boys acted as controls. At the end of one year, analysis of the changes in scores using analysis of covariance (ANCOVA on the Eurofit fitness tests showed that the intervention group had made statistically significant improvement on all tests other than flexibility. These improvements were also significantly better than controls. This type of intervention appears to be an effective addition to standard fitness training in order to help children with autism improve their fitness levels.

  12. European programme towards the 1 MeV ITER NB injector

    Energy Technology Data Exchange (ETDEWEB)

    Masiello, A. [Fusion for Energy, C/Josep Pla 2, 08019 Barcelona (Spain)], E-mail: antonio.masiello@f4e.europa.eu; Agarici, G.; Bonicelli, T.; Simon, M. [Fusion for Energy, C/Josep Pla 2, 08019 Barcelona (Spain); Antoni, V. [Consorzio RFX, Euratom-ENEA Association, C.so Stati Uniti 4, I-35126, Padova (Italy); De Esch, H. [Association EURATOM, CEA Cadarache, IRFM/SCCP, 13108 St. Paul Lez Durance (France); De Lorenzi, A. [Consorzio RFX, Euratom-ENEA Association, C.so Stati Uniti 4, I-35126, Padova (Italy); Dremel, M. [Forschungszentrum Karlsruhe, EURATOM Association, 76021 Karlsruhe (Germany); Franzen, P. [Max-Planck-Institut fur Plasmaphysik, EURATOM Association, D-85740, Garching (Germany); Hemsworth, R. [ITER, ITER Joint Work Site, CEA Cadarache, 13108 St. Paul Lez Durance (France); Liniers, M. [Association EURATOM-CIEMAT, Av. Complutense 22, 28040, Madrid (Spain); Marcuzzi, D. [Consorzio RFX, Euratom-ENEA Association, C.so Stati Uniti 4, I-35126, Padova (Italy); Martin, D. [UKAEA Fusion Association, Culham Science Centre, Abingdon, OX14 3DB (United Kingdom); Piovan, R. [Consorzio RFX, Euratom-ENEA Association, C.so Stati Uniti 4, I-35126, Padova (Italy); Simonin, A. [Association EURATOM, CEA Cadarache, IRFM/SCCP, 13108 St. Paul Lez Durance (France); Sonato, P. [Consorzio RFX, Euratom-ENEA Association, C.so Stati Uniti 4, I-35126, Padova (Italy); Surrey, E. [UKAEA Fusion Association, Culham Science Centre, Abingdon, OX14 3DB (United Kingdom); Svensson, L. [Association EURATOM, CEA Cadarache, IRFM/SCCP, 13108 St. Paul Lez Durance (France); Tanga, A. [ITER, ITER Joint Work Site, CEA Cadarache, 13108 St. Paul Lez Durance (France); Toigo, V. [Consorzio RFX, Euratom-ENEA Association, C.so Stati Uniti 4, I-35126, Padova (Italy)] (and others)

    2009-06-15

    The ITER neutral beam (NB) system presents several challenges and a robust program is necessary in order to achieve the requirements within the tight constraints due to the ITER construction plan. The establishment of full scale NB test facilities (NBTF) has therefore become a centre piece of the international NB development strategy. This paper describes the status of the design activities that have been undertaken in Europe to develop the components for the heating NB injectors along with the main plans and results of the R and D activities. A description of the programme towards the establishment of the test facilities and the planned activities is also reported.

  13. Programme impact on current contraception in Bangladesh.

    Science.gov (United States)

    Latif, M A

    1994-03-01

    "This paper analyses the impact of three credit programmes--the Bangladesh Rural Advancement Committee (BRAC), the Bangladesh Rural Development Board's Rural Development-12 (BRDB RD-12), and the Grameen Bank (GB), on current rate of contraception. These programmes are targeted to alleviate poverty by providing group-based credit to the rural poor in creating self employment opportunities. With small credits, these programmes combine family planning activities in terms of consciousness raising, awareness building and motivation. Sample survey data are used to analyse the problem of impact evaluation. The analyses show that the BRAC and the GB programmes have [a] significantly positive impact on the current rate of contraception, while the BRDB RD-12 programme does not have any such impact. It is also found that education, both of female[s] and male[s] separately, and child survivorship have independently positive impact[s] on current contraception."

  14. The BGAN extension programme

    Science.gov (United States)

    Rivera, Juan J.; Trachtman, Eyal; Richharia, Madhavendra

    2005-11-01

    Mobile satellite telecommunications systems have undergone an enormous evolution in the last decades, with the interest in having advanced telecommunications services available on demand, anywhere and at any time, leading to incredible advances. The demand for braodband data is therefore rapidly gathering pace, but current solutions are finding it increasingly difficult to combine large bandwidth with ubiquitous coverage, reliability and portability. The BGAN (Broadband Global Area Network) system, designed to operate with the Inmarsat-4 satellites, provides breakthrough services that meet all of these requirements. It will enable broadband connection on the move, delivering all the key tools of the modern office. Recognising the great impact that Inmarsat's BGAN system will have on the European satellite communications industry, and the benefits that it will bring to a wide range of European industries, in 2003 ESA initiated the "BGAN Extension" project. Its primary goals are to provide the full range of BGAN services to truly mobile platforms, operating in aeronautical, vehicular and maritime environments, and to introduce a multicast service capability. The project is supported by the ARTES Programme which establishes a collaboration agreement between ESA, Inmarsat and a group of key industrial and academic institutions which includes EMS, Logica, Nera and the University of Surrey (UK).

  15. 12 CFR 225.145 - Limitations established by the Competitive Equality Banking Act of 1987 on the activities and...

    Science.gov (United States)

    2010-01-01

    ... established in Dimension. Under this test, a commercial loan would not include, for example, an open-market... brokerage investment advisory services, underwriting or dealing in government securities as permissible for... result of market or technological innovation are similarly permitted to the extent that they do...

  16. A proposed adaptation of the European Foundation for Quality Management Excellence Model to physical activity programmes for the elderly - development of a quality self-assessment tool using a modified Delphi process

    Directory of Open Access Journals (Sweden)

    Marques Ana I

    2011-09-01

    Full Text Available Abstract Background There has been a growing concern in designing physical activity (PA programmes for elderly people, since evidence suggests that such health promotion interventions may reduce the deleterious effects of the ageing process. Complete programme evaluations are a necessary prerequisite to continuous quality improvements. Being able to refine, adapt and create tools that are suited to the realities and contexts of PA programmes for the elderly in order to support its continuous improvement is, therefore, crucial. Thus, the aim of this study was to develop a self-assessment tool for PA programmes for the elderly. Methods A 3-round Delphi process was conducted via the Internet with 43 national experts in PA for the elderly, management and delivery of PA programmes for the elderly, sports management, quality management and gerontology, asking experts to identify the propositions that they considered relevant for inclusion in the self-assessment tool. Experts reviewed a list of proposed statements, based on the criteria and sub-criteria from the European Foundation for Quality Management Excellence Model (EFQM and PA guidelines for older adults and rated each proposition from 1 to 8 (disagree to agree and modified and/or added propositions. Propositions receiving either bottom or top scores of greater than 70% were considered to have achieved consensus to drop or retain, respectively. Results In round 1, of the 196 originally-proposed statements (best practice principles, the experts modified 41, added 1 and achieved consensus on 93. In round 2, a total of 104 propositions were presented, of which experts modified 39 and achieved consensus on 53. In the last round, of 51 proposed statements, the experts achieved consensus on 19. After 3 rounds of rating, experts had not achieved consensus on 32 propositions. The resulting tool consisted of 165 statements that assess nine management areas involved in the development of PA programmes for

  17. Programmable Logic Controllers.

    Science.gov (United States)

    Insolia, Gerard; Anderson, Kathleen

    This document contains a 40-hour course in programmable logic controllers (PLC), developed for a business-industry technology resource center for firms in eastern Pennsylvania by Northampton Community College. The 10 units of the course cover the following: (1) introduction to programmable logic controllers; (2) DOS primer; (3) prerequisite…

  18. Stages and methodology of experimental work on professional development of specialists of preschool educational establishments in the field of educationally-health activity

    Directory of Open Access Journals (Sweden)

    Makovetskaya N.V.

    2012-10-01

    Full Text Available The stages of experimental work are certain on professional development of educators and instructors of physical culture of preschool educational establishments in the field of to educationally-health-improvement to activity. The method of this work is resulted. 266 specialists of preschool educational establishments were plugged in research. From them 139 belonged to the experimental group, 127 - to control. The level of their professional development was determined on such components: motivational, activity, cognitive, personality. A forming experiment foresaw application of model of organization of methodical work with specialists in preschool educational establishment. Organizational and methodical terms are selected for professional development of specialists: development of maintenance, determination of forms (methods and features of professional development. It was instrumental in the considerable increase of level of professional development of respondents of experimental group.

  19. Blood Establishment Registration Database

    Data.gov (United States)

    U.S. Department of Health & Human Services — This application provides information for active, inactive, and pre-registered firms. Query options are by FEI, Applicant Name, Establishment Name, Other Names,...

  20. A process evaluation of a supervisory development programme

    Directory of Open Access Journals (Sweden)

    Jasper Buys

    2012-07-01

    Full Text Available Orientation: An important evaluation function is to assess the adequacy of the programme process, including the extent to which the appropriate people participate in its activities.Research purpose: The study aimed to provide information about coverage, service delivery, organisational resources, and medium-term outcomes for a supervisory development programme (SDP in the hospitality industry.Motivation for the study: The primary motivation was to assist programme staff to understand their programme and also to generate information that the programme staff could use to reflect on the programme’s performance and future direction.Research design, approach and method: A mixture of quantitative and qualitative methods was employed, namely: a literature review; personal interviews; and internal programme documentation, such as e-mail correspondence, financial statements, attendance registers, and personnel records. Personal interviews were conducted with two stakeholders, namely the programme manager and programme administrator. The programme data of 69 participants in the SDP were utilised for the evaluation.Main findings: The evaluation’s main finding concluded that the ‘implemented programme’ was not congruent with the ‘planned programme’.Practical/managerial implications: It is recommended that programme activities and theory should be re-evaluated, as the programme is used mainly as a training programme for new appointees, rather than a management development programme to create a pool of potential supervisors. Programme uptake and output should also be closely aligned. The length of time that people in the pool of potential supervisors had to wait before they were appointed should also be reduced.Contribution/value-add: By explicating the basic programme theory and studying programme implementation, this evaluation serves as a starting point for future evaluations of the SDP.

  1. Informationist programme in support of biomedical research: a programme description and preliminary findings of an evaluation.

    Science.gov (United States)

    Whitmore, Susan C; Grefsheim, Suzanne F; Rankin, Jocelyn A

    2008-06-01

    The informationist programme at the Library of the National Institutes of Health (NIH) in Bethesda, MD, USA has grown to 14 informationists working with 40 clinical and basic science research teams. This case report, intended to contribute to the literature on informationist programmes, describes the NIH informationist programme, including implementation experiences, the informationists' training programme, their job responsibilities and programme outcomes. The NIH informationist programme was designed to enhance the library's service capacity. Over time, the steps for introducing the service to new groups were formalized to ensure support by leadership, the team being served and the library. Job responsibilities also evolved from traditional library roles to a wide range of knowledge management activities. The commitment by the informationist, the team and the library to continuous learning is critical to the programme's success. RESULTS / OUTCOMES: NIH scientists reported that informationists saved them time and contributed to teamwork with expert searching and point-of-need instruction. Process evaluation helped refine the programme. High-level, preliminary outcomes were identified from a survey of scientists receiving informationist services, along with key informant interviews. Process evaluation examined service implementation, informationists' training and service components. Anecdotal evidence has also indicated a favourable response to the programme.

  2. 34 CFR 299.3 - What priority may the Secretary establish for activities in an Empowerment Zone or Enterprise...

    Science.gov (United States)

    2010-07-01

    ... activities in an Empowerment Zone or Enterprise Community? 299.3 Section 299.3 Education Regulations of the... activities in an Empowerment Zone or Enterprise Community? For any ESEA discretionary grant program, the... significant portion of the program funds to address substantial problems in an Empowerment Zone, including...

  3. Integrating active restoration with environmental flows to improve native riparian tree establishment in the Colorado River Delta

    Science.gov (United States)

    Schlatter, Karen; Grabau, Matthew R.; Shafroth, Patrick B.; Zamora-Arroyo, Francisco

    2017-01-01

    Drastic alterations to river hydrology, land use change, and the spread of the nonnative shrub, tamarisk (Tamarix spp.), have led to the degradation of riparian habitat in the Colorado River Delta in Mexico. Delivery of environmental flows to promote native cottonwood (Populus spp.) and willow (Salix spp.) recruitment in human-impacted riparian systems can be unsuccessful due to flow-magnitude constraints and altered abiotic–biotic feedbacks. In 2014, an experimental pulse flow of water was delivered to the Colorado River in Mexico as part of the U.S.-Mexico binational agreement, Minute 319. We conducted a field experiment to assess the effects of vegetation removal, seed augmentation, and environmental flows, separately and in combination, on germination and first-year seedling establishment of cottonwood, willow, and tamarisk at five replicate sites along 5 river km. The relatively low-magnitude flow deliveries did not substantively restore natural fluvial processes of erosion, sediment deposition, and vegetation scour, but did provide wetted surface soils, shallow groundwater, and low soil salinity. Cottonwood and willow only established in wetted, cleared treatments, and establishment was variable in these treatments due to variable site conditions and inundation duration and timing. Wetted soils, bare surface availability, soil salinity, and seed availability were significant factors contributing to successful cottonwood and willow germination, while soil salinity and texture affected seedling persistence over the growing season. Tamarisk germinated and persisted in a wider range of environmental conditions than cottonwood and willow, including in un-cleared treatment areas. Our results suggest that site management can increase cottonwood and willow recruitment success from low-magnitude environmental flow events, an approach that can be applied in other portions of the Delta and to other human-impacted riparian systems across the world with similar

  4. Perspectives on a Whole Class Mindfulness Programme

    Science.gov (United States)

    Thomas, George; Atkinson, Cathy

    2017-01-01

    This study sought to establish pupil and teacher views about a six-hour, whole-class mindfulness programme called Paws.b. Pupil post-intervention focus groups and teacher semi-structured interviews were used to ascertain what was interesting and useful about Paws.b, and how it could be developed. Audio recordings were transcribed and thematically…

  5. Influence of motive activity on forming of proof skills of healthy way of life of students of higher educational establishments.

    Directory of Open Access Journals (Sweden)

    Trotsenko V.V.

    2010-08-01

    Full Text Available The estimation and the analysis of impellent activity of students is considered. The importance of impellent activity in forming a healthy way of life of students is shown. In research the data of questionnaire of students are used. sports priorities of students are revealed should to undertake in attention by development of the program of physical training. The wide spectrum of the reasons which interfere with exercises is revealed. These reasons should be considered during individual work with each student. It is proved, that impellent activity influences forming of proof skills of a healthy way of life of students.

  6. [Work organisation improvement methods applied to activities of Blood Transfusion Establishments (BTE): Lean Manufacturing, VSM, 5S].

    Science.gov (United States)

    Bertholey, F; Bourniquel, P; Rivery, E; Coudurier, N; Follea, G

    2009-05-01

    Continuous improvement of efficiency as well as new expectations from customers (quality and safety of blood products) and employees (working conditions) imply constant efforts in Blood Transfusion Establishments (BTE) to improve work organisations. The Lean method (from "Lean" meaning "thin") aims at identifying wastages in the process (overproduction, waiting, over-processing, inventory, transport, motion) and then reducing them in establishing a mapping of value chain (Value Stream Mapping). It consists in determining the added value of each step of the process from a customer perspective. Lean also consists in standardizing operations while implicating and responsabilizing all collaborators. The name 5S comes from the first letter of five operations of a Japanese management technique: to clear, rank, keep clean, standardize, make durable. The 5S method leads to develop the team working inducing an evolution of the way in the management is performed. The Lean VSM method has been applied to blood processing (component laboratory) in the Pays de la Loire BTE. The Lean 5S method has been applied to blood processing, quality control, purchasing, warehouse, human resources and quality assurance in the Rhône-Alpes BTE. The experience returns from both BTE shows that these methods allowed improving: (1) the processes and working conditions from a quality perspective, (2) the staff satisfaction, (3) the efficiency. These experiences, implemented in two BTE for different processes, confirm the applicability and usefulness of these methods to improve working organisations in BTE.

  7. Microbial inoculants and organic amendment improves the establishment of autochtonous shrub species and microbial activity recovery in a semiarid soil

    Science.gov (United States)

    Mengual, Carmen; Schoebitz, Mauricio; Azcon, Rosario; Torres, Pilar; Caravaca, Fuensanta; Roldan, Antonio

    2014-05-01

    The re-establishment of autochthonous shrub species is an essential strategy for recovering degraded soils under semiarid Mediterranean conditions. A field assay was carried out to determine the combined effects of the inoculation with native rhizobacteria (B. megaterium, Enterobacter sp, B. thuringiensis and Bacillus sp) and the addition of composted sugar beet (SB) residue on physicochemical soil properties and Lavandula dentata L. establishment. One year after planting, Bacillus sp. and B. megaterium+SB were the most effective treatments for increasing shoot dry biomass (by 5-fold with respect to control) and Enterobacter sp+SB was the most effective treatments for increasing dry root biomass. All the treatments evaluated significantly increased the foliar nutrient content (NPK) compared to control values (except B. thuringiensis+SB). The organic amendment had significantly increased available phosphorus content in rhizosphere soil by 29% respect to the control. Enterobacter sp combined with sugar beet residue improved total N content in soil (by 46% respect to the control) as well as microbiological and biochemical properties. The selection of the most efficient rhizobacteria strains and their combined effect with organic residue seems to be a critical point that drives the effectiveness of using these biotechnological tools for the revegetation and rehabilitation of degraded soils under semiarid conditions.

  8. Why people co-produce within activation services: the necessity of motivation and trust – an investigation of selection biases in a municipal activation programme in the Netherlands

    NARCIS (Netherlands)

    Fledderus, J.; Honingh, M.E.

    2016-01-01

    Activation services that aim at re-employment of jobseekers often suffer from ‘creaming’, i.e. selecting those who have the best qualifications to re-enter the labour market. New ways of delivery, such as co-production, are supposed to be less subject to selection mechanisms. To analyse whether

  9. The European Framework Programme under way

    CERN Multimedia

    2007-01-01

    The new European Framework Programme - FP7 - has recently started and will offer various possibilities for CERN to participate in EU co-funded projects for research and technological development. In December 2006, the Council of the European Union (EU) formally adopted the 7th European Framework Programme for research, technological development and demonstration activities (FP7). FP7 started on 1 January 2007 and will cover the period 2007 to 2013. With a total budget of 50.5 B-Euros, FP7 is the largest Framework Programme in the history of the EU. FP7 consists of four major sub-programmes, referred to as 'Specific Programmes'. 'Cooperation' is focused on collaborative research and is divided into 10 research themes. 'Ideas' is a new EU programme for funding of frontier research in all fields of science. 'Capacities' aims at strengthening the research capacities in Europe. Finally, 'People' succeeds the previous Marie Curie Programmes and targets the development of Europe's human potential. On 22 December...

  10. The European Framework Programme under way

    CERN Multimedia

    2007-01-01

    The new European Framework Programme - FP7 - has recently started and will offer various possibilities for CERN to participate in EU co-funded projects for research and technological development. In December 2006, the Council of the European Union (EU) formally adopted the 7th European Framework Programme for research, technological development and demonstration activities (FP7). FP7 started on 1st January 2007 and will cover the period 2007 to 2013. With a total budget of 50.5 billion euros, FP7 is the largest Framework Programme in the history of the EU. FP7 consists of four major sub-programmes, referred to as 'Specific Programmes'. 'Cooperation' is focused on collaborative research and is divided into 10 research themes. 'Ideas' is a new EU programme for funding frontier research in all fields of science. 'Capacities' aims at strengthening the research capacities in Europe. Finally, 'People' succeeds the previous Marie Curie Programmes and targets the development of Europe's human potential. On 22 Decem...

  11. National and regional asthma programmes in Europe

    Directory of Open Access Journals (Sweden)

    Olof Selroos

    2015-09-01

    Full Text Available This review presents seven national asthma programmes to support the European Asthma Research and Innovation Partnership in developing strategies to reduce asthma mortality and morbidity across Europe. From published data it appears that in order to influence asthma care, national/regional asthma programmes are more effective than conventional treatment guidelines. An asthma programme should start with the universal commitments of stakeholders at all levels and the programme has to be endorsed by political and governmental bodies. When the national problems have been identified, the goals of the programme have to be clearly defined with measures to evaluate progress. An action plan has to be developed, including defined re-allocation of patients and existing resources, if necessary, between primary care and specialised healthcare units or hospital centres. Patients should be involved in guided self-management education and structured follow-up in relation to disease severity. The three evaluated programmes show that, thanks to rigorous efforts, it is possible to improve patients' quality of life and reduce hospitalisation, asthma mortality, sick leave and disability pensions. The direct and indirect costs, both for the individual patient and for society, can be significantly reduced. The results can form the basis for development of further programme activities in Europe.

  12. Photovoltaic programme, edition 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This comprehensive publication issued by the Swiss Federal Office of Energy's Photovoltaics (PV) Programme presents an overview (in English) of activities and projects in the photovoltaics research and pilot and demonstration areas in Switzerland for the year 2003. Progress in future solar cell technologies as well as in the area of modules, building integration and system technologies is summarised. Also, national and international co-operation and multi-national pilot and demonstration projects are commented on. Associated projects such as eco-balances for PV systems, forecasting and modelling tools as well as system monitoring tools are discussed. In the area of pilot and demonstration projects, component development, PV integration in sloping roofs, on flat roofs and on facades as well as further PV plant are looked at. Also, measurement campaigns, studies, statistics and other PV-related topics are summarised. This volume presents a list of 92 projects in the PV area including the appropriate Internet links and is completed with a collection of project abstracts.

  13. FAST joins Breakthrough programme

    Science.gov (United States)

    Banks, Michael

    2016-11-01

    The 180m Five-hundred-meter Aperture Spherical radio Telescope (FAST) - the world's largest single-aperture radio receiver - has become part of the Breakthrough Listen programme, which launched in July 2015 to look for intelligent life beyond Earth.

  14. Programmable mechanical metamaterials

    NARCIS (Netherlands)

    Florijn, H.C.B.

    2016-01-01

    We present a novel strategy to overcome this limitation and create programmable me chanical metamaterials, where the response of a single structure is determined and can be changed by the amount of lateral confinement.

  15. Elukestva õppe programm : Erasmus+

    Index Scriptorium Estoniae

    2014-01-01

    Erasmus+ programm liidab senised koostööprogrammid „Euroopa elukestva õppe programm“, „Euroopa Noored“ ning Euroopa komisjoni rahvusvahelised kõrgharidusprogrammid. Elukestva õppe programmi 2013 kokkuvõte

  16. The HAWC GRB Programme

    Science.gov (United States)

    Lennarz, D.; Taboada, I.

    2016-10-01

    HAWC is a very-high-energy gamma-ray extensive air shower detector located in central Mexico at an altitude of 4,100 m above sea level. This contribution summarises recent results of the HAWC GRB programme.

  17. National programme for prevention of burn injuries

    Directory of Open Access Journals (Sweden)

    Gupta J

    2010-10-01

    Full Text Available The estimated annual burn incidence in India is approximately 6-7 million per year. The high incidence is attributed to illiteracy, poverty and low level safety consciousness in the population. The situation becomes further grim due to the absence of organized burn care at primary and secondary health care level. But the silver lining is that 90% of burn injuries are preventable. An initiative at national level is need of the hour to reduce incidence so as to galvanize the available resources for more effective and standardized treatment delivery. The National Programme for Prevention of Burn Injuries is the endeavor in this line. The goal of National programme for prevention of burn injuries (NPPBI would be to ensure prevention and capacity building of infrastructure and manpower at all levels of health care delivery system in order to reduce incidence, provide timely and adequate treatment to burn patients to reduce mortality, complications and provide effective rehabilitation to the survivors. Another objective of the programme will be to establish a central burn registry. The programme will be launched in the current Five Year Plan in Medical colleges and their adjoining district hospitals in few states. Subsequently, in the next five year plan it will be rolled out in all the medical colleges and districts hospitals of the country so that burn care is provided as close to the site of accident as possible and patients need not to travel to big cities for burn care. The programme would essentially have three components i.e. Preventive programme, Burn injury management programme and Burn injury rehabilitation programme.

  18. Visual Basic educational programme

    OpenAIRE

    Pranaitis, Arūnas

    2005-01-01

    Visual basic educational programme Informational Technologies has become such a popular subject that they are applied in all works of life. However, Informational Technologies are still rarely used in the lessons at school. There are such reasons of the mentioned issue: · Insufficient base of computers, · The old software and its disadvantages, · The lack of computerized educational programmes. The aim of the work was to prove that it is actual to create computerized educat...

  19. Motivation programmes of organizations

    OpenAIRE

    Pízová, Tereza

    2008-01-01

    The Bachelor Thesis "'Motivation Programmes of Organizations" focuses on an extremely important area within personnel management. Employee motivation is crucial to the effective operation of businesses. Motivation programmes assist in increasing and maintaining employee motivation and demonstrate an organization's interest in its employees. This piece is on one hand concerned with theoretical foundations of motivation, describing theories and concepts important to the area of human behaviour ...

  20. Punch Card Programmable Microfluidics

    OpenAIRE

    George Korir; Manu Prakash

    2014-01-01

    Small volume fluid handling in single and multiphase microfluidics provides a promising strategy for efficient bio-chemical assays, low-cost point-of-care diagnostics and new approaches to scientific discoveries. However multiple barriers exist towards low-cost field deployment of programmable microfluidics. Incorporating multiple pumps, mixers and discrete valve based control of nanoliter fluids and droplets in an integrated, programmable manner without additional required external component...

  1. The Gold Standard Programme

    DEFF Research Database (Denmark)

    Neumann, Tim; Rasmussen, Mette; Ghith, Nermin

    2013-01-01

    To evaluate the real-life effect of an evidence-based Gold Standard Programme (GSP) for smoking cessation interventions in disadvantaged patients and to identify modifiable factors that consistently produce the highest abstinence rates.......To evaluate the real-life effect of an evidence-based Gold Standard Programme (GSP) for smoking cessation interventions in disadvantaged patients and to identify modifiable factors that consistently produce the highest abstinence rates....

  2. Behavioural activity of wild rabbits (Oryctolagus cuniculus under semi-natural rearing systems: establishing a seasonal pattern

    Directory of Open Access Journals (Sweden)

    Carlos Díez Valle

    2013-12-01

    Full Text Available The activity of 2 populations of wild rabbits (Oryctolagus cuniculus, L. 1758, consisting of 14 adults (>9 mo of age each (4 males and 10 females, was analysed over 2 consecutive years. Rabbits were captured in the wild and kept in 2 separate enclosures of 0.5 ha, with each enclosure divided into 2 zones: a smaller area where warrens were located (breeding area and a larger area where food and water were provided (feeding area. Seven rabbits in each enclosure were individually tagged with a microchip (2 males and 5 females and, after installing 2 detection devices, it was possible to identify which of the 2 areas they were located in and record the length of time spent in each. To regulate the size of the breeding population, young rabbits produced in the enclosures were captured and removed regularly. Considering the number of movements between areas and the time spent in the feeding area, a circadian activity pattern was found, reporting 2 maximum activity peaks coinciding with twilight (18.35% of the total movements, 6-8 a.m. and daybreak (22.95%, 7-10 p.m. while activity was dramatically decreased during the midday hours (1.86%, 10 a.m.-4 p.m.. Rabbits displayed a seasonal pattern throughout the year, with maximum activity levels during winter (45.76% of the total movements, January-March and spring (42.91%, April-June, which could be related to higher reproductive activity at this time of the year as a higher breeding output was reported in June and September. The levels of activity exhibited by males (13.44% daily activity rate were significantly higher than those displayed by females (9.80%. No significant differences were found regarding time spent on the feeding area in relation to season or gender. The average duration of each foray to the feeding area was higher during the summer, higher for females than males and higher during the middle of the night than the rest of the day.

  3. Programmable Multi-Chip Module

    Science.gov (United States)

    Kautz, David; Morgenstern, Howard; Blazek, Roy J.

    2004-11-16

    A multi-chip module comprising a low-temperature co-fired ceramic substrate having a first side on which are mounted active components and a second side on which are mounted passive components, wherein this segregation of components allows for hermetically sealing the active components with a cover while leaving accessible the passive components, and wherein the passive components are secured using a reflow soldering technique and are removable and replaceable so as to make the multi-chip module substantially programmable with regard to the passive components.

  4. HADES RV Programme with HARPS-N at TNG . III. Flux-flux and activity-rotation relationships of early-M dwarfs

    Science.gov (United States)

    Maldonado, J.; Scandariato, G.; Stelzer, B.; Biazzo, K.; Lanza, A. F.; Maggio, A.; Micela, G.; González-Álvarez, E.; Affer, L.; Claudi, R. U.; Cosentino, R.; Damasso, M.; Desidera, S.; González Hernández, J. I.; Gratton, R.; Leto, G.; Messina, S.; Molinari, E.; Pagano, I.; Perger, M.; Piotto, G.; Rebolo, R.; Ribas, I.; Sozzetti, A.; Suárez Mascareño, A.; Zanmar Sanchez, R.

    2017-01-01

    Context. Understanding stellar activity in M dwarfs is crucial for the physics of stellar atmospheres and for ongoing radial velocity exoplanet programmes. Despite the increasing interest in M dwarfs, our knowledge of the chromospheres of these stars is far from being complete. Aims: We test whether the relations between activity, rotation, and stellar parameters and flux-flux relationships previously investigated for main-sequence FGK stars and for pre-main-sequence M stars also hold for early-M dwarfs on the main-sequence. Although several attempts have been made so far, here we analyse a large sample of stars undergoing relatively low activity. Methods: We analyse in a homogeneous and coherent way a well-defined sample of 71 late-K/early-M dwarfs that are currently being observed in the framework of the HArps-N red Dwarf Exoplanet Survey (HADES). Rotational velocities are derived using the cross-correlation technique, while emission flux excesses in the Ca ii H & K and Balmer lines from Hα up to Hɛ are obtained by using the spectral subtraction technique. The relationships between the emission excesses and the stellar parameters (projected rotational velocity, effective temperature, kinematics, and age) are studied. Relations between pairs of fluxes of different chromospheric lines (flux-flux relationships) are also studied and compared with the literature results for other samples of stars. Results: We find that the strength of the chromospheric emission in the Ca ii H & K and Balmer lines is roughly constant for stars in the M0-M3 spectral range. Although our sample is likely to be biased towards inactive stars, our data suggest that a moderate but significant correlation between activity and rotation might be present, as well as a hint of kinematically selected young stars showing higher levels of emission in the calcium line and in most of the Balmer lines. We find our sample of M dwarfs to be complementary in terms of chromospheric and X-ray fluxes with

  5. A Compact, Waveguide Based Programmable Optical Comb Generator Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This NASA Phase I STTR effort will establish the feasibility of developing a compact broadband near to mid-IR programmable optical comb for use in laser based remote...

  6. Sustainable practice change: Professionals' experiences with a multisectoral child health promotion programme in Sweden

    Directory of Open Access Journals (Sweden)

    Mogren Ingrid

    2011-03-01

    Full Text Available Abstract Background New methods for prevention and health promotion and are constantly evolving; however, positive outcomes will only emerge if these methods are fully adopted and sustainable in practice. To date, limited attention has been given to sustainability of health promotion efforts. This study aimed to explore facilitators, barriers, and requirements for sustainability as experienced by professionals two years after finalizing the development and implementation of a multisectoral child health promotion programme in Sweden (the Salut programme. Initiated in 2005, the programme uses a 'Salutogenesis' approach to support health-promoting activities in health care, social services, and schools. Methods All professionals involved in the Salut Programme's pilot areas were interviewed between May and September 2009, approximately two years after the intervention package was established and implemented. Participants (n = 23 were midwives, child health nurses, dental hygienists/dental nurses, and pre-school teachers. Transcribed data underwent qualitative content analysis to illuminate perceived facilitators, barriers, and requirements for programme sustainability. Results The programme was described as sustainable at most sites, except in child health care. The perception of facilitators, barriers, and requirements were largely shared across sectors. Facilitators included being actively involved in intervention development and small-scale testing, personal values corresponding to programme intentions, regular meetings, working close with collaborators, using manuals and a clear programme branding. Existing or potential barriers included insufficient managerial involvement and support and perceived constraints regarding time and resources. In dental health care, barriers also included conflicting incentives for performance. Many facilitators and barriers identified by participants also reflected their perceptions of more general and forthcoming

  7. Sustainable practice change: professionals' experiences with a multisectoral child health promotion programme in Sweden.

    Science.gov (United States)

    Edvardsson, Kristina; Garvare, Rickard; Ivarsson, Anneli; Eurenius, Eva; Mogren, Ingrid; Nyström, Monica E

    2011-03-22

    New methods for prevention and health promotion and are constantly evolving; however, positive outcomes will only emerge if these methods are fully adopted and sustainable in practice. To date, limited attention has been given to sustainability of health promotion efforts. This study aimed to explore facilitators, barriers, and requirements for sustainability as experienced by professionals two years after finalizing the development and implementation of a multisectoral child health promotion programme in Sweden (the Salut programme). Initiated in 2005, the programme uses a 'Salutogenesis' approach to support health-promoting activities in health care, social services, and schools. All professionals involved in the Salut Programme's pilot areas were interviewed between May and September 2009, approximately two years after the intervention package was established and implemented. Participants (n = 23) were midwives, child health nurses, dental hygienists/dental nurses, and pre-school teachers. Transcribed data underwent qualitative content analysis to illuminate perceived facilitators, barriers, and requirements for programme sustainability. The programme was described as sustainable at most sites, except in child health care. The perception of facilitators, barriers, and requirements were largely shared across sectors. Facilitators included being actively involved in intervention development and small-scale testing, personal values corresponding to programme intentions, regular meetings, working close with collaborators, using manuals and a clear programme branding. Existing or potential barriers included insufficient managerial involvement and support and perceived constraints regarding time and resources. In dental health care, barriers also included conflicting incentives for performance. Many facilitators and barriers identified by participants also reflected their perceptions of more general and forthcoming requirements for programme sustainability. These

  8. Modelling Landscape Dynamics in a Highland Mediterranean Catchment: Establishing the impact of Climate Variation and Human Activity

    NARCIS (Netherlands)

    Beek, L.P.H. van; Feiken, H.; Asch, Th.W.J. van; Bierkens, M.F.P.

    2012-01-01

    The close link between human occupancy and the Mediterranean landscape has long been recognized. Through the exploitation of the various but fragmented resources that these landscapes have to offer, man has been able to secure a living. However, these activities are often marginal and small shifts i

  9. Survey of radiation protection programmes for transport; Etude des programmes de radioprotection pour les transports de matieres radioactives

    Energy Technology Data Exchange (ETDEWEB)

    Lizot, M.T.; Perrin, M.L.; Sert, G. [CEA Fontenay-aux-Roses, Inst. de Protection et de Surete Nucleaire, Dept. de Protection et de Surete Nucleaire, 92 (France); Lange, F.; Schwarz, G.; Feet, H.J.; Christ, R. [Gesellschaft fur Anlagen-und Reaktorsicherheit, GRS, mbH, Cologne (Germany); Shaw, K.B.; Hughes, J.S.; Gelder, R. [National Radiological Protection Board (NRPB), Oxon, OX (United Kingdom)

    2001-07-01

    The survey of radiation protection programmes for transport has been jointly performed by three scientific organisations I.P.S.N. (France), G.R.S. ( Germany), and N.R.P.B. (United kingdom) on behalf of the European Commission and the pertaining documentation summarises the findings and conclusions of the work that was undertaken with the principal objectives to provide guidance on the establishment, implementation and application of radiation protection programmes for the transport of radioactive materials by operators and the assessment and evaluation of such programmes by the competent authority and to review currently existing radiation protection programmes for the transport of radioactive materials. (N.C.)

  10. Serological evidence of continuing high Usutu virus (Flaviviridae) activity and establishment of herd immunity in wild birds in Austria.

    Science.gov (United States)

    Meister, Tanja; Lussy, Helga; Bakonyi, Tamás; Sikutová, Silvie; Rudolf, Ivo; Vogl, Wolfgang; Winkler, Hans; Frey, Hans; Hubálek, Zdenek; Nowotny, Norbert; Weissenböck, Herbert

    2008-03-18

    Usutu virus (USUV), family Flaviviridae, has been responsible for avian mortality in Austria from 2001 to 2006. The proportion of USUV-positive individuals among the investigated dead birds decreased dramatically after 2004. To test the hypothesis that establishment of herd immunity might be responsible, serological examinations of susceptible wild birds were performed. Blood samples of 442 wild birds of 55 species were collected in 4 consecutive years (2003--2006). In addition, 86 individuals from a birds of prey rehabilitation centre were bled before, at the peak, and after the 2005 USUV transmission season in order to identify titre dynamics and seroconversions. The haemagglutination inhibition test was used for screening and the plaque reduction neutralization test for confirmation. While in the years 2003 and 2004 the proportion of seropositive wild birds was 50% in 2005 and 2006. At the birds of prey centre, almost three quarters of the owls and raptors exhibited antibodies before the 2005 transmission season; this percentage dropped to less than half at the peak of USUV transmission and raised again to almost two thirds after the transmission season. These data show a from year to year continuously increasing proportion of seropositive wild birds. The owl and raptor data indicate significant viral exposure in the previous season(s), but also a number of new infections during the current season, despite the presence of antibodies in some of these birds. Herd immunity is a possible explanation for the significant decrease in USUV-associated bird mortalities in Austria during the recent years.

  11. Mechanisms of change of a novel weight loss programme provided by a third sector organisation: a qualitative interview study.

    Science.gov (United States)

    McMahon, Naoimh E; Visram, Shelina; Connell, Louise A

    2016-05-10

    There is a need for theory-driven studies that explore the underlying mechanisms of change of complex weight loss programmes. Such studies will contribute to the existing evidence-base on how these programmes work and thus inform the future development and evaluation of tailored, effective interventions to tackle overweight and obesity. This study explored the mechanisms by which a novel weight loss programme triggered change amongst participants. The programme, delivered by a third sector organisation, addressed both diet and physical activity. Over a 26 week period participants engaged in three weekly sessions (education and exercise in a large group, exercise in a small group and a one-to-one education and exercise session). Novel aspects included the intensity and duration of the programme, a competitive selection process, milestone physical challenges (e.g. working up to a 5 K and 10 K walk/run during the programme), alumni support (face-to-face and online) and family attendance at exercise sessions. Data were collected through interviews with programme providers (n = 2) and focus groups with participants (n = 12). Discussions were audio-recorded, transcribed and analysed using NVivo10. Published behaviour change frameworks and behaviour change technique taxonomies were used to guide the coding process. Clients' interactions with components of the weight loss programme brought about a change in their commitment, knowledge, beliefs about capabilities and social and environmental contexts. Intervention components that generated these changes included the competitive selection process, group and online support, family involvement and overcoming milestone challenges over the 26 week programme. The mechanisms by which these components triggered change differed between participants. There is an urgent need to establish robust interventions that can support people who are overweight and obese to achieve a healthy weight and maintain this change. Third

  12. Modelling Landscape Dynamics in a Highland Mediterranean Catchment: Establishing the impact of Climate Variation and Human Activity

    OpenAIRE

    L. P. H. van Beek; (Rik) Feiken, H.; Asch, Th. W. J. van; Bierkens, M.F.P.

    2012-01-01

    The close link between human occupancy and the Mediterranean landscape has long been recognized. Through the exploitation of the various but fragmented resources that these landscapes have to offer, man has been able to secure a living. However, these activities are often marginal and small shifts in population pressure, corresponding land use patterns or climatic variability can have large consequences on the redistribution of water and sediment in these areas.

  13. Control programme for cystic echinococcosis in Uruguay

    Directory of Open Access Journals (Sweden)

    Pilar Irabedra

    2016-06-01

    Full Text Available Cystic echinococcosis is a highly endemic parasitic zoonosis that is present in the Southern Cone countries of America. For several decades, various prevention and control programmes have been implemented in different countries and regions, with varying results. In Uruguay, a new control programme was implemented in 2006 that employed new strategies for canine diagnosis and treatment, dog population control, diagnosis in humans, epidemiological surveillance, and health education, including community participation. The control programme in Uruguay addresses the control and surveillance of the disease from a holistic perspective based on Primary Health Care, which has strengthened the community’s participation in developing and coordinating activities in an interdisciplinary manner. Similarly, the control programme that is currently implemented is based on a risk-focused approach. The surveillance and control measures were focused on small villages and extremely poor urban areas. In this study, the strategies used and the results obtained from 2008-2013 are analysed and discussed.

  14. Control programme for cystic echinococcosis in Uruguay

    Science.gov (United States)

    Irabedra, Pilar; Ferreira, Ciro; Sayes, Julio; Elola, Susana; Rodríguez, Miriam; Morel, Noelia; Segura, Sebastian; dos Santos, Estela; Guisantes, Jorge A

    2016-01-01

    Cystic echinococcosis is a highly endemic parasitic zoonosis that is present in the Southern Cone countries of America. For several decades, various prevention and control programmes have been implemented in different countries and regions, with varying results. In Uruguay, a new control programme was implemented in 2006 that employed new strategies for canine diagnosis and treatment, dog population control, diagnosis in humans, epidemiological surveillance, and health education, including community participation. The control programme in Uruguay addresses the control and surveillance of the disease from a holistic perspective based on Primary Health Care, which has strengthened the community’s participation in developing and coordinating activities in an interdisciplinary manner. Similarly, the control programme that is currently implemented is based on a risk-focused approach. The surveillance and control measures were focused on small villages and extremely poor urban areas. In this study, the strategies used and the results obtained from 2008-2013 are analysed and discussed. PMID:27223652

  15. Control programme for cystic echinococcosis in Uruguay.

    Science.gov (United States)

    Irabedra, Pilar; Ferreira, Ciro; Sayes, Julio; Elola, Susana; Rodríguez, Miriam; Morel, Noelia; Segura, Sebastian; Santos, Estela Dos; Guisantes, Jorge A

    2016-05-24

    Cystic echinococcosis is a highly endemic parasitic zoonosis that is present in the Southern Cone countries of America. For several decades, various prevention and control programmes have been implemented in different countries and regions, with varying results. In Uruguay, a new control programme was implemented in 2006 that employed new strategies for canine diagnosis and treatment, dog population control, diagnosis in humans, epidemiological surveillance, and health education, including community participation. The control programme in Uruguay addresses the control and surveillance of the disease from a holistic perspective based on Primary Health Care, which has strengthened the community's participation in developing and coordinating activities in an interdisciplinary manner. Similarly, the control programme that is currently implemented is based on a risk-focused approach. The surveillance and control measures were focused on small villages and extremely poor urban areas. In this study, the strategies used and the results obtained from 2008-2013 are analysed and discussed.

  16. The development and pilot testing of the Self-management Programme of Activity, Coping and Education for Chronic Obstructive Pulmonary Disease (SPACE for COPD

    Directory of Open Access Journals (Sweden)

    Apps LD

    2013-07-01

    Full Text Available Lindsay D Apps,1 Katy E Mitchell,1 Samantha L Harrison,1 Louise Sewell,1 Johanna E Williams,1 Hannah ML Young,1 Michael Steiner,1 Mike Morgan,1 Sally J Singh1,2 1National Institute of Health Research CLAHRC-LNR Pulmonary Rehabilitation Research Group, University Hospitals of Leicester NHS, Leicester, UK; 2Applied Research Centre, Health and Lifestyle Interventions, Coventry University, Coventry, UK Purpose: There is no independent standardized self-management approach available for chronic obstructive pulmonary disease (COPD. The aim of this project was to develop and test a novel self-management manual for individuals with COPD. Patients: Participants with a confirmed diagnosis of COPD were recruited from primary care. Methods: A novel self-management manual was developed with health care professionals and patients. Five focus groups were conducted with individuals with COPD (N = 24 during development to confirm and enhance the content of the prototype manual. The Self-management Programme of Activity, Coping and Education for Chronic Obstructive Pulmonary Disease (SPACE for COPD manual was developed as the focus of a comprehensive self-management approach facilitated by health care professionals. Preference for delivery was initial face-to-face consultation with telephone follow-up. The SPACE for COPD manual was piloted with 37 participants in primary care. Outcome measures included the Self-Report Chronic Respiratory Questionnaire, Incremental Shuttle Walk Test, and Endurance Shuttle Walking Test (ESWT; measurements were taken at baseline and 6 weeks. Results: The pilot study observed statistically significant improvements for the dyspnea domain of the Self-Report Chronic Respiratory Questionnaire and ESWT. Dyspnea showed a mean change of 0.67 (95% confidence interval 0.23–1.11, P = 0.005. ESWT score increased by 302.25 seconds (95% confidence interval 161.47–443.03, P < 0.001. Conclusion: This article describes the development and

  17. The INTEGRAL Core Observing Programme

    OpenAIRE

    Winkler, C; Gehrels, N.; Lund, N.; Schoenfelder, V.; Ubertini, P.

    1999-01-01

    The Core Programme of the INTEGRAL mission is defined as the portion of the scientific programme covering the guaranteed time observations for the INTEGRAL Science Working Team. This paper describes the current status of the Core Programme preparations and summarizes the key elements of the observing programme.

  18. Magnetic-activated cell sorting (MACS) can be used as a large-scale method for establishing zebrafish neuronal cell cultures

    OpenAIRE

    Georg Welzel; Daniel Seitz; Stefan Schuster

    2015-01-01

    Neuronal cell cultures offer a crucial tool to mechanistically analyse regeneration in the nervous system. Despite the increasing importance of zebrafish (Danio rerio) as an in vivo model in neurobiological and biomedical research, in vitro approaches to the nervous system are lagging far behind and no method is currently available for establishing enriched neuronal cell cultures. Here we show that magnetic-activated cell sorting (MACS) can be used for the large-scale generation of neuronal-r...

  19. HISTORICAL FRAGMENTS OF ESTABLISHMENT OF "MAGARACH" SCIENTIFIC INSTITUTE OF GRAPES AND WINE AND THE ELEMENTS OF ITS SCIENTIFIC ACTIVITY

    Directory of Open Access Journals (Sweden)

    Klimova-Donchouk L. B.

    2015-11-01

    Full Text Available The article presents historical information about the stages of gradual transformation of the first non-large wine-making institution of Crimea, organized in 1828 under the initiative of Prince M.S. Vorontsov in the natural boundary called Magarach near the Imperial Nikitsky botanical garden in the world famous Institute of Grape and Wine "Magarach" - once the chief coordinator of the research work in the field of viticulture and winemaking republics of the USSR and the main forge of scientific staff in this direction. Among the directors of the institute of the last century, there were such talented organizers as A.G. Globa, T.G. Kataryan, P.Y. Golodriga. The Institute operated a network of regional branches, created enotec with a settled in 1836 wine Muscat pink Magarach (World rarity is reflected in the Guinness book of records, the world ampelographic collection (fourth in number of samples, scientists developed area-standard assortment for production, issued 11 Volumes of "Ampelography of USSR" (awarded by OIV, designed a lot of outstanding for yield and stability varieties (Pervenets Magaracha, Ranniy Magaracha, Citron Magaracha et al. and clones (Muscat white of Red Stone, Pinot Noir yields and others. grapes. There was a significant contribution in the sphere of research and development of viticulture and winemaking of world, the institute was given an international prestige and this led to establishing the base of the General Assembly of the OIV - International Organization of Grape and Wine, the International Symposium on the selection of wine-town, several international wine tasting competitions and International finest examples of table grapes

  20. The development of entrepreneurial capacity and business activity of students of educational establishments using information and communication technologies

    Directory of Open Access Journals (Sweden)

    L. A. Danchenok

    2016-01-01

    Full Text Available The article is devoted to problems of organizational and methodical process modeling of the entrepreneurial potential and business activity of students of educational institutions through the use of Smart-technologies. It is noted that the successful implementation of enterprise and business projects are the basis of economic development of society, with the main factor for the development of entrepreneurship in the country in the long term is to develop the entrepreneurial mindset of young people. Entrepreneurial younger generation reserve created for the period of study, will provide the subsequent decades of business operation, incomenot only to the owner, but also the composition of personnel of the company and, in general, the country. The specifics of perception of the new generation of knowledge, learning and the formation of professional skills is that their effectiveness depends, sometimes completely determined by the degree of use of information and communication technologies, not only in the preparation and implementation of knowledge by the learners, but also in the work themselves teachers. Therefore, an effective and modern instrument for achieving the development goals of the business potential and business students to provide such forms of work with students, which would stimulate their interest in entrepreneurship through the active use of information technologies. The organizational and methodological training model and a set of measures aimed at developing the entrepreneurial potential and business activity of the young generation. To a large extent the elements of our model successfully implemented in REU them. GV Plekhanov at the Faculty of “Marketing Business School and Entrepreneurship”, to carry out training business technologies in relevant areas of knowledge for the information society and the modern state of the economy – business intelligence, innovation and creative business, crisis and risk management

  1. Establishment of a transgenic yeast screening system for estrogenicity and identification of the anti-estrogenic activity of malachite green.

    Science.gov (United States)

    Jiao, Baowei; Yeung, Eric K C; Chan, Chi Bun; Cheng, Christopher H K

    2008-12-15

    Endocrine disruptors refer to chemical compounds in the environment which interfere with the endocrine systems of organisms. Among them, environmental estrogens pose serious problems to aquatic organisms, in particular fish. It is therefore important and necessary to have a fast and low-cost system to screen the large number of different chemical compounds in the aquatic environment for their potential endocrine disrupting actions. In this study, a screening platform was developed to detect xenoestrogens in the aquatic environment using the fission yeast Schizosaccharomyces pombe, and applied for compound screening. The aim was to demonstrate any significant potential differences between the fish screening system and the human screening system. To this end, a yeast expression vector harboring a fish estrogen receptor alpha and a reporter vector containing the estrogen responsive element fused with the Escherichia coli LacZ gene were constructed. After transformation with these two vectors, the transformed yeast clones were confirmed by Western blotting and selected on the basis of the beta-galactosidase activity. In this transgenic yeast system, the natural estrogen (estradiol) and other known xenoestrogens such as diethylstilbestrol, bisphenol A, genistein and dichloro-diphenyl-trichloroethane exhibited dose-dependent activities. Using this system, more than 40 putative endocrine disruptors including phytoestrogens, pesticides, herbicides, industrial dyes and other industrial chemicals were screened. Ten of them were demonstrated to exhibit estrogenic actions. Industrial dyes such as malachite green (MG) that disrupt thyroid hormone synthesis are extensively used and are widely distributed in the aquatic environment. Using this system, MG did not show any estrogenic action, but was demonstrated to exhibit anti-estrogenic activity.

  2. The Importance of Establishing and Maintaining Continuity of Knowledge during 21st Century Nuclear Fuel Cycle Activities

    Energy Technology Data Exchange (ETDEWEB)

    Pickett, Chris A [ORNL; Rowe, Nathan C [ORNL; Younkin, James R [ORNL; Wishard, Bernard [International Atomic Energy Agency (IAEA); Bean, Robert [U.S. Department of Energy, NNSA; Blair, Dianna [Sandia National Laboratories (SNL); Lawson, Ray [Savannah River National Laboratory (SRNL); Weeks, George [Savannah River National Laboratory (SRNL); Tolk, Keith [Milagro Consulting

    2012-01-01

    During this century, the entire nuclear fuel cycle will expand and become increasingly more global, taxing both the resources and capabilities of the International Atomic Energy Agency (IAEA) to maintain an effective Continuity of Knowledge (CoK) and its ability to provide timely detection of diversion. Uranium that currently is mined and milled in one country will be converted, enriched, and fabricated into fuel for reactors in an expanding set of new countries. This expansion will make it harder to guarantee that regional activities stay regional and that diversion detection is timely unless new and sustainable tools are developed to improve inspector effectiveness. To deal with this emerging reality, the IAEA must increase its use of unattended monitoring and employ new tools and methods that enhance CoK during all phases of the fuel cycle. This approach will help provide useful information to aid in detecting undeclared activities and create opportunities for timely and appropriate responses to events well before they enter phases of greater concern (e.g., enrichment). The systems that maintain CoK of safeguarded assets rely on containment and surveillance (C/S) technologies. The 21st century fuel cycle will require increased use of these technologies and systems, plus greater implementation of unattended systems that can securely collect data when inspectors are not present.

  3. Preliminary Screening of Antioxidant and Antibacterial Activities and Establishment of an Efficient Callus Induction in Curculigo latifolia Dryand (Lemba

    Directory of Open Access Journals (Sweden)

    Reza Farzinebrahimi

    2016-01-01

    Full Text Available Leaf, seed, and tuber explants of C. latifolia were inoculated on MS medium supplemented with various concentrations of BAP and IBA, alone or in combinations, to achieve in vitro plant regeneration. Subsequently, antioxidant and antibacterial activities were determined from in vitro and in vivo plant developed. No response was observed from seed culture on MS media with various concentrations of PGRs. The highest percentage of callus was observed on tuber explants (94% and leaf explants (89% when cultured on MS media supplemented with IBA in combination with BAP. A maximum of 88% shoots per tuber explant, with a mean number of shoots (8.8±1.0, were obtained on MS medium supplemented with combinations of BAP and IBA (2.5 mg L−1. The best root induction (92% and mean number (7.6±0.5 from tuber explants were recorded on 2.5 mg L−1 IBA alone supplemented to MS medium. The higher antioxidant content (80% was observed from in vivo tuber. However, tuber part from the intact plant showed higher inhibition zone in antibacterial activity compared to other in vitro and in vivo tested parts.

  4. Establishment of a reference interval for natural killer cell activity through flow cytometry and its clinical application in the diagnosis of hemophagocytic lymphohistiocytosis.

    Science.gov (United States)

    Chung, H J; Park, C J; Lim, J H; Jang, S; Chi, H S; Im, H J; Seo, J J

    2010-04-01

    Recently, the Histiocyte Society revised the diagnostic criteria for hemophagocytic lymphohistiocytosis (HLH) to include low or absent natural killer (NK) cell activity, according to local laboratory reference. The aim of this study was to establish reference interval for functional NK-cell activity in 63 healthy Korean individuals using a flow-cytometric assay. We used peripheral blood mononuclear cells (PBMCs) as effector cells and Fluorescein isothiocyanate-labeled K562 cells as target cells. NK-cell activity was calculated using the following equation: NK-cell activity (%) = (test lysis - spontaneous lysis) x 100/(maximum lysis - spontaneous lysis). NK-cell activity was analyzed in 13 known HLH patients and 16 suspected non-HLH patients using a flow-cytometric assay. The mean (+/-SD) cytotoxicity of PBMCs from healthy individuals was 20.9 +/- 5.3% and the reference interval was 11.8-31.9%. The mean NK-cell activity of HLH patients (8.3 +/- 8.9%) was significantly lower (P = 0.001) than that of non-HLH patients (20.1 +/- 7.8%). The sequential changes in NK-cell activity in the HLH group corresponded to clinical and laboratory findings following treatment. We successfully developed a functional NK-cell activity test for use in the clinical laboratory and obtained a reference interval of NK-cell activity from healthy donors. This assay, and associated reference interval, was used to analyze 30 clinically relevant specimens and the results were shown to be well correlated.

  5. 'It's like a personal motivator that you carried around wi' you': utilising self-determination theory to understand men's experiences of using pedometers to increase physical activity in a weight management programme.

    Science.gov (United States)

    Donnachie, Craig; Wyke, Sally; Mutrie, Nanette; Hunt, Kate

    2017-05-05

    Self-monitoring using pedometers is an effective behaviour change technique to support increased physical activity (PA). However, the ways in which pedometers operate as motivational tools in adoption and maintenance of PA is not well understood. This paper investigates men's experiences of pedometers as motivational tools both during and after their participation in a 12-week group-based, weight management programme for overweight/obese men, Football Fans in Training (FFIT). Semi-structured telephone interviews were conducted with 28 men, purposively sampled to include men who did and did not achieve 5% weight loss during the programme. Data were analysed thematically utilising the framework approach, using Self-Determination Theory (SDT) - namely concepts of behavioural regulation and the basic needs of relatedness, competence and autonomy - as an analytical lens. During the programme, FFIT's context and fellow participants supported relatedness and encouraged use of the pedometer. The pedometer was seen to provide tangible proof of progress, thus increasing competence for change, whilst the ability to monitor one's own progress and take remedial action supported autonomy; these men portrayed the pedometer as an 'ally'. However, a minority found the pedometer 'dispiriting' or controlling when it evidenced their inability to meet their PA targets. After the programme, some men no longer used the device as they had fully internalised their motivations for increased PA. In contrast, others continued to use pedometers or progressed to other self-monitoring technologies because it was enjoyable and facilitated maintenance of their increased PA. However, the minority of men who experienced the pedometer as controlling no longer used it. They were less successful in achieving 5% weight loss and appeared reliant on external factors, including support from coach and group members, to maintain motivation. These findings show how self-monitoring using pedometers and

  6. The impact of four family support programmes for people with a disability in Ireland.

    LENUS (Irish Health Repository)

    Daly, Louise

    2015-03-01

    This article reports on an evaluation of four family support programmes in Ireland for families of people with a physical or an intellectual disability or autism. The focus of the evaluation, which took place within a year of the programmes\\' completion, was on establishing whether the programmes had an impact on families\\' capacity to effectively support their family member.

  7. Establishing the NeuroRecovery Network: multisite rehabilitation centers that provide activity-based therapies and assessments for neurologic disorders.

    Science.gov (United States)

    Harkema, Susan J; Schmidt-Read, Mary; Behrman, Andrea L; Bratta, Amy; Sisto, Sue Ann; Edgerton, V Reggie

    2012-09-01

    The mission of the NeuroRecovery Network (NRN) is to provide support for the implementation of specialized centers at rehabilitation sites in the United States. Currently, there are 7 NRN centers that provide standardized activity-based interventions designed from scientific and clinical evidence for recovery of mobility, posture, standing, and walking and improvements in health and quality of life in individuals with spinal cord injury. Extensive outcome measures evaluating function, health, and quality of life are used to determine the efficacy of the program. NRN members consist of scientists, clinicians, and administrators who collaborate to achieve the goals and objectives of the network within an organizational structure by designing and implementing a clinical model that provides consistent interventions and evaluations and a general education and training program. Copyright © 2012 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  8. Effectiveness of a universal parental support programme to promote healthy dietary habits and physical activity and to prevent overweight and obesity in 6-year-old children: the Healthy School Start Study, a cluster-randomised controlled trial.

    Science.gov (United States)

    Nyberg, Gisela; Sundblom, Elinor; Norman, Åsa; Bohman, Benjamin; Hagberg, Jan; Elinder, Liselotte Schäfer

    2015-01-01

    To develop and evaluate the effectiveness of a parental support programme to promote healthy dietary and physical activity habits and to prevent overweight and obesity in Swedish children. A cluster-randomised controlled trial was carried out in areas with low to medium socio-economic status. Participants were six-year-old children (n = 243) and their parents. Fourteen pre-school classes were randomly assigned to intervention (n = 7) and control groups (n = 7). The intervention lasted for 6 months and included: 1) Health information for parents, 2) Motivational Interviewing with parents and 3) Teacher-led classroom activities with children. Physical activity was measured by accelerometry, dietary and physical activity habits and parental self-efficacy through a questionnaire. Body weight and height were measured and BMI standard deviation score was calculated. Measurements were conducted at baseline, post-intervention and at 6-months follow-up. Group differences were examined using analysis of covariance and Poisson regression, adjusted for gender and baseline values. There was no significant intervention effect in the primary outcome physical activity. Sub-group analyses showed a significant gender-group interaction in total physical activity (TPA), with girls in the intervention group demonstrating higher TPA during weekends (p = 0.04), as well as in sedentary time, with boys showing more sedentary time in the intervention group (p = 0.03). There was a significantly higher vegetable intake (0.26 servings) in the intervention group compared to the control group (p = 0.003). At follow-up, sub-group analyses showed a sustained effect for boys. The intervention did not affect the prevalence of overweight or obesity. It is possible to influence vegetable intake in children and girls' physical activity through a parental support programme. The programme needs to be intensified in order to increase effectiveness and sustain the effects long-term. These findings are an

  9. Effectiveness of a universal parental support programme to promote healthy dietary habits and physical activity and to prevent overweight and obesity in 6-year-old children: the Healthy School Start Study, a cluster-randomised controlled trial.

    Directory of Open Access Journals (Sweden)

    Gisela Nyberg

    Full Text Available To develop and evaluate the effectiveness of a parental support programme to promote healthy dietary and physical activity habits and to prevent overweight and obesity in Swedish children.A cluster-randomised controlled trial was carried out in areas with low to medium socio-economic status. Participants were six-year-old children (n = 243 and their parents. Fourteen pre-school classes were randomly assigned to intervention (n = 7 and control groups (n = 7. The intervention lasted for 6 months and included: 1 Health information for parents, 2 Motivational Interviewing with parents and 3 Teacher-led classroom activities with children. Physical activity was measured by accelerometry, dietary and physical activity habits and parental self-efficacy through a questionnaire. Body weight and height were measured and BMI standard deviation score was calculated. Measurements were conducted at baseline, post-intervention and at 6-months follow-up. Group differences were examined using analysis of covariance and Poisson regression, adjusted for gender and baseline values.There was no significant intervention effect in the primary outcome physical activity. Sub-group analyses showed a significant gender-group interaction in total physical activity (TPA, with girls in the intervention group demonstrating higher TPA during weekends (p = 0.04, as well as in sedentary time, with boys showing more sedentary time in the intervention group (p = 0.03. There was a significantly higher vegetable intake (0.26 servings in the intervention group compared to the control group (p = 0.003. At follow-up, sub-group analyses showed a sustained effect for boys. The intervention did not affect the prevalence of overweight or obesity.It is possible to influence vegetable intake in children and girls' physical activity through a parental support programme. The programme needs to be intensified in order to increase effectiveness and sustain the effects long-term. These findings

  10. Swedish support programme on nuclear non-proliferation in Central and Eastern Europe and Central Asia

    Energy Technology Data Exchange (ETDEWEB)

    Ek, P.; Andersson, Sarmite [Swedish Nuclear Power Inspectorate, Stockholm (Sweden); Wredberg, L. [ILG Consultant Ltd., Vienna (Austria)

    2000-06-15

    convinced understanding and opinion of the Swedish Support Programme Management that the States in question are seriously motivated and are carrying out an ambitious work to develop and improve their national non-proliferation regimes, in spite of their shortcomings concerning financial and human resources. For those States, with which Sweden has established support and co-operation programmes with 'full-scope' non-proliferation objectives, it is judged that the goals reached, up till now, are very satisfactory, and that the States in question have come a long way towards the fulfilment of international requirements. The Programme is now entering a third phase and the future Programme plans are currently under consideration. A broad outlook of the future activities is made in chapter D of this report.

  11. Impact of a school-based intervention on nutritional education and physical activity in primary public schools in Chile (KIND) programme study protocol: cluster randomised controlled trial

    OpenAIRE

    Bustos, Nelly; Olivares, Sonia; Leyton, Bárbara; Cano, Marcelo; Albala,Cecilia

    2016-01-01

    Background Chile has suffered a fast increase in childhood obesity in the last 10 years. As a result, several school programmes have been implemented, however the effectiveness of these needs to be evaluated to identify and prioritize strategies to curve this trend. Methods Cluster randomized controlled trial. Twelve primary public schools chosen at random over three regions of the country will take part in this study. The sample size consisted of a total of 1,655 children. For each region on...

  12. South African antarctic biological research programme

    CSIR Research Space (South Africa)

    SASCAR

    1981-07-01

    Full Text Available This document provides a description of the past, current and planned South African biological research activities in the sub-Antarctic and Antarctic regions. Future activities will fall under one of the five components of the research programme...

  13. Establishment of activity indicator of TiO{sub 2} photocatalytic reaction-Hydroxyl radical trapping method

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Chen-Yu, E-mail: cychang@mdu.edu.tw [Department of Life Science, Ming-Dao University, 369 Wen-Hua Road, Peetow, Chang-Hua County 52345, Taiwan (China); Hsieh, Yung-Hsu [Department of Environmental Engineering, National Chung-Hsing University, 250 Kuo-Kuang Road, Taichung, Taiwan (China); Hsieh, Ling-Ling [Department of Radiological Technology, Central Taiwan University of Sciences and Technology, 11 Pu-Tze Lane, Pei-Tun District, Taichung, Taiwan (China); Yao, Kuo-Shan; Cheng, Ta-Chih [Department of Life Science, Ming-Dao University, 369 Wen-Hua Road, Peetow, Chang-Hua County 52345, Taiwan (China)

    2009-07-30

    In this study, a new, low cost and easy method, hydroxyl radical trapping method, was employed to investigate the photo-activity of UV/TiO{sub 2} photocatalytic reaction. The Taguchi method was utilized to optimize the preparation of titanium dioxide (TiO{sub 2}) thin-film reactor through the modified chemical vapor deposition (CVD) method. The optimal yield of hydroxyl radicals was then evaluated by calculating the conversion ratio of salicylic acid under the optimal conditions. In the experiments, salicylic acid was used as the free-radical scavenger and the formation of three different intermediates were examined to shed light on the trend and kinetics of reaction of hydroxyl radical with organic substance under different operation conditions. The results indicated that the yield of hydroxyl radicals increased with increasing irradiation intensity and dissolved oxygen level. The optimal experimental conditions obtained in this study were irradiation with intensity of 2.9 mW cm{sup -2} on salicylic acid at concentration of 250 mg L{sup -1} by both agitation and aeration processes (dissolved oxygen level = 8.2 mg O{sub 2} L{sup -1}) at pH 5. Such conditions could achieve the optimal hydroxyl radical yield of 5.1 x 10{sup -17} M.

  14. Punch Card Programmable Microfluidics

    CERN Document Server

    Korir, George

    2014-01-01

    Small volume fluid handling in single and multiphase microfluidics provides a promising strategy for efficient bio-chemical assays, low-cost point-of-care diagnostics and new approaches to scientific discoveries. However multiple barriers exist towards low-cost field deployment of programmable microfluidics. Incorporating multiple pumps, mixers and discrete valve based control of nanoliter fluids and droplets in an integrated, programmable manner without additional required external components has remained elusive. Combining the idea of punch card programming with arbitrary fluid control, here we describe a self-contained, hand-crank powered, multiplex and robust programmable microfluidic platform. A paper tape encodes information as a series of punched holes. A mechanical reader/actuator reads these paper tapes and correspondingly executes a series of operations onto a microfluidic chip coupled to the platform in a plug-and-play fashion. Enabled by the complexity of codes that can be represented by a series ...

  15. Evaluation of service users' experiences of participating in an exercise programme at the Western Australian State Forensic Mental Health Services.

    Science.gov (United States)

    Wynaden, Dianne; Barr, Lesley; Omari, Omar; Fulton, Anthony

    2012-06-01

    Approximately 210 patients are admitted each year to the Western Australian State Forensic Mental Health Service, and most present with psychotic illness, along with other physical and mental comorbidities. In 2010, a healthy lifestyle programme, which included a formal exercise programme coordinated by an exercise physiologist, was introduced at the service. A self-report questionnaire was developed to obtain feedback on the programme, and 56 patients completed the questionnaire during the 6-month evaluation period. As well as providing patients with access to regular physical activity, the programme also supports the recovery philosophy, where patients work in partnership with forensic mental health staff. Overall, patients reported that the programme assisted them to manage their psychiatric symptoms, as well as improving their level of fitness, confidence, and self-esteem. In addition, patients received education about the importance of regular exercise to their mental health, and the role exercise plays in preventing chronic illness and obesity. While the benefits of exercise on mental health outcomes for people with depression and anxiety are well established, this evaluation adds to the evidence that such programmes provide similar benefits to people who have a psychotic illness and are hospitalized in an acute secure setting.

  16. The volunteer programme ‘Night Ravens’:

    DEFF Research Database (Denmark)

    Larsen, Britt Østergaard; Bendix Kleif, Helle; Kolodziejczyk, Christophe

    2015-01-01

    The volunteer programme ‘Night Ravens’ (NR) was founded in Sweden in 1987 and has, over the years, developed into a Scandinavian concept covering large areas of Sweden, Denmark, Norway, Greenland and the Faroe Islands. The NR programme is a crime prevention initiative with adults walking the stre......The volunteer programme ‘Night Ravens’ (NR) was founded in Sweden in 1987 and has, over the years, developed into a Scandinavian concept covering large areas of Sweden, Denmark, Norway, Greenland and the Faroe Islands. The NR programme is a crime prevention initiative with adults walking...... the streets at night in identifiable ‘uniforms’ in areas with high activity. The purpose of this study is to evaluate the effects of the NR programme in Denmark based on a volunteer set-up with a less intrusive approach to situational crime prevention than, for instance, hot spot policing. The analyses...... with NR organizations to districts without NR organizations. The results show no difference in the crime rates between Danish postcode districts with and without the NR programme. Hence, we cannot identify positive effects of situational crime prevention when evaluating this Scandinavian volunteer...

  17. Setting up a structured laboratory mentoring programme

    Directory of Open Access Journals (Sweden)

    Talkmore Maruta

    2013-03-01

    Full Text Available Introduction: Laboratory mentoring programmes can be an important vehicle to establish and solidify quality management systems and help laboratories achieve accreditation goals. Different mentoring approaches have been used with varying levels of success. The authors provide a guide to implementing a structured laboratory mentorship programme based on their practical field experience.Method: The study is based on experience in Lesotho as well as subsequent roll out of a similar approach in the other African countries of Zimbabwe, Mozambique, Swaziland and Cameroon between 2009 and 2011.Summary: We highlight critical elements to consider when setting up a long-term, sustainable and well-structured mentorship programme. These elements include: well-defined goals; sufficient length of mentor engagement on site; standardised approach across laboratories; measurement of progress using standardised tools; well-structured reporting mechanisms; alignment of the programme with overall Ministry of Health plans; and selection and training of the mentors. These elements will differ in application, depending on countries’ needs and available resources. A structured approach allows for scalability, comparison across laboratories and countries and an easier approach to budgeting and planning for countries intending to set up similar programmes.

  18. Air Quality Monitoring Programme

    DEFF Research Database (Denmark)

    Kemp, K.; Palmgren, F.

    The Danish Air Quality Monitoring Programme (LMP IV) has been revised in accordance with the Framework Directive and the first three daughter directives of SO2, NOx/NO2, PM10, lead, benzene, CO and ozone. PM10 samplers are under installation and the installation will be completed during 2002....... The PM10 results from 2000 are spares, only TSP are thus included in this report. The data sets for year 2000 is complete for many stations. The monitoring programme consists of 10 stations plus 2 extra stations under the Municipality of Copenhagen. The SO2 and lead levels are still decreasing and far...

  19. A programmer's geometry

    CERN Document Server

    Bowyer, Adrian

    1983-01-01

    A Programmer's Geometry provides a guide in programming geometric shapes. The book presents formulas and examples of computer representation and coding of geometry. Each of the nine chapters of the text deals with the representation and solution of a specific geometrical problem, such as areas, vectors, and volumes. The last chapter provides a brief discussion on generating image through a computer. The codes presented in the book are written in FORTRAN 77. The text will be of great use to programmers who are working on projects that involve geometric calculations.

  20. Computer mathematics for programmers

    CERN Document Server

    Abney, Darrell H; Sibrel, Donald W

    1985-01-01

    Computer Mathematics for Programmers presents the Mathematics that is essential to the computer programmer.The book is comprised of 10 chapters. The first chapter introduces several computer number systems. Chapter 2 shows how to perform arithmetic operations using the number systems introduced in Chapter 1. The third chapter covers the way numbers are stored in computers, how the computer performs arithmetic on real numbers and integers, and how round-off errors are generated in computer programs. Chapter 4 details the use of algorithms and flowcharting as problem-solving tools for computer p

  1. 母猪猪瘟、口蹄疫血清抗体与乳中母源抗体的相关性分析及其免疫程序制定%Correlative analysis of sow fever,aftosa serum antibody and maternal antibody and the establishment of its immune programme

    Institute of Scientific and Technical Information of China (English)

    黄卫平; 庞继光

    2011-01-01

    This experiment actualized immunization on the sows in the same period with different time, dosage and 'number of times. It was found that the serum antibody inoreased with the enhance of dosage and number of times, the time of immunizaiton had no influence on the efficiency of serum antibody, but the parturition rate of sows, which immunized with sow fever vaccine in gestation period were lower than that of the nonpregnant period immune; the sow fever and aftosa whey antibody were strongly relevant to serum antibody on the parturition day, and the related coefficients were 0.986 3 and 0.670 9. Meanwhile, the sow fever and aftosa immune programme of Liangshan prefecture was established based on the experiment results.%本试验采用不同的免疫时间、剂量和次数对同期后备母猪进行免疫,发现母猪分娩当天血清抗体水平随着免疫次数和免疫剂量的增加而增大;免疫时间不影响母猪的血清抗体水平,但在妊娠期进行猪瘟疫苗免疫的母猪的分娩率低于空怀期免疫的母猪;分娩当天乳清中的猪瘟、口蹄疫母源抗体与血清抗体呈强相关,其相关系数为0.9863和0.6709。同时,依据试验结果确定了凉山州规模化猪场母猪的免疫程序。

  2. Correlation of priority lines of personality with the level of motivation of schoolboys to the specially organized motive activity, depending on the type of educational establishment.

    Directory of Open Access Journals (Sweden)

    Fedorenko E.O.

    2011-05-01

    Full Text Available Considered and analysed influencing of features educational-organizational process on forming of priority lines of personality and level of motivation student to the specially organized motive activity. In experiment took part 101 senior pupils. Information of the questionnaire questioning in which students were determine the priority lines of personality and priorities during conducting of leisure is utillized in research. The presence of connections is certain between the level of motivation to the specially organized motive activity and lines personalities which student senior classes determine priority. It is proved that on intercommunication of lines of personality with the level of motivation to employments differences influence motive activity in organization of educational process of educational establishment.

  3. Establishing a baseline for monitoring and evaluating user satisfaction with climate services in Tanzania

    OpenAIRE

    2016-01-01

    This report is an output from the Global Framework for Climate Services Adaptation Program in Africa (GFCS-APA) Tanzania country activities. The aim of the report is to establish a baseline for monitoring “User Satisfaction with Climate Services” at the national, district, and local levels, with a focus on the programme target districts of Longido and Kiteto. A qualitative approach was employed to document 1) existing institutional coordination and steering mechanisms for a dedicated climate ...

  4. Advanced energy systems and technologies research in Finland. NEMO-2 Programme Annual Report 1996-1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-10-01

    Advanced energy technologies were linked to the national energy research in the beginning of 1988 when energy research was reorganised in Finland. The Ministry of Trade and Industry established several energy research programmes and NEMO was one of them. Major objectives of the programme were to assess the potential of new energy systems for the national energy supply system and to promote industrial activities. Within the NEMO 2 programme for the years 1993-1998, research was focused on a few promising technological solutions. In the beginning of 1995, the national energy research activities were passed on to the Technology Development Centre TEKES. The NEMO 2 programme is directed towards those areas that have particular potential for commercial exploitation or development. Emphasis is placed particularly on solar and wind energy, as well as supporting technologies, such as energy storage and hydrogen technology. Resources have been focused on three specific areas: arctic wind technology, wind turbine components, and the integration of solar energy into applications (including thin film solar cells). In Finland, the growth of the new energy technology industry is concentrated on these areas. The turnover of the Finnish industry has been growing considerably due to the national research activities and support of technology development. The sales have increased more than 10 times compared with the year 1987 and is now over 300 million FIM. The support to industries and their involvement in the program has grown considerably. In this report, the essential research projects of the programme during 1996-1997 are described. The total funding for these projects was about 30 million FIM per year, of which the TEKES`s share was about 40 per cent. The programme consists of 10 research projects, some 15 joint development projects, and 9 EU projects. In case the research projects and joint development projects are acting very closely, the description of the project is

  5. An oxidative burst and its attenuation by bacterial peroxidase activity is required for optimal establishment of the Arachis hypogaea-Bradyrhizobium sp. symbiosis.

    Science.gov (United States)

    Muñoz, V; Ibáñez, F; Figueredo, M S; Fabra, A

    2016-07-01

    The main purpose of this study was to determine whether the Arachis hypogaea L. root oxidative burst, produced at early stages of its symbiotic interaction with Bradyrhizobium sp. SEMIA 6144, and the bacterial antioxidant system are required for the successful development of this interaction. Pharmacological approaches were used to reduce both plant oxidative burst and bacterial peroxidase enzyme activity. In plants whose H2 O2 levels were decreased, a low nodule number, a reduction in the proportion of red nodules (%) and an increase in the bacteroid density were found. The symbiotic phenotype of plants inoculated with a Bradyrhizobium sp. SEMIA 6144 culture showing decreased peroxidase activity was also affected, since the biomass production, nodule number and percentage of red nodules in these plants were lower than in plants inoculated with Bradyrhizobium sp. control cultures. We demonstrated for the first time that the oxidative burst triggered at the early events of the symbiotic interaction in peanut, is a prerequisite for the efficient development of root nodules, and that the antioxidant system of bradyrhizobial peanut symbionts, particularly the activity of peroxidases, is counteracting this oxidative burst for the successful establishment of the symbiosis. Our results provide new insights into the mechanisms involved in the development of the symbiotic interaction established in A. hypogaea L. a legume infected in an intercellular way. © 2016 The Society for Applied Microbiology.

  6. A programmable molecular robot.

    Science.gov (United States)

    Muscat, Richard A; Bath, Jonathan; Turberfield, Andrew J

    2011-03-09

    We have developed a programmable and auton-omous molecular robot whose motion is fueled by DNA hybridization. Instructions determining the path to be followed are programmed into the fuel molecules, allowing precise control of cargo motion on a branched track.

  7. User programmable virtualized networks

    NARCIS (Netherlands)

    Meijer, R.J.; Strijkers, R.J.; Gommans, L.; Laat, C.de

    2006-01-01

    This paper introduces the concept of a User Programmable Virtualized Network, which allows networks to deliver application specific services using network element components that developers can program as part of a users application. The use of special tokens in data or control packets is the basis

  8. Progressive Retirement Programme

    CERN Multimedia

    HR Department

    2009-01-01

    Following the Standing Concertation Committee meeting of 2 December 2008, please note that the Progressive Retirement Programme has been extended by one year, i.e. until 31 March 2010. Further information is available on : https://hr-services.web.cern.ch/hr-services/services-Ben/prp/prp.asp HR Department, tel. 73903

  9. The European Programme Manager

    DEFF Research Database (Denmark)

    Larson, Anne; Bergman, E.; Ehlers, S.;

    The publication is a result of a cooperation between organisations in six European countries with the aim to develop a common European education for programme managers. It contains of a description of the different elements of the education together with a number of case-studies from the counties...

  10. Air Quality Monitoring Programme

    DEFF Research Database (Denmark)

    Kemp, K.; Palmgren, F.

    The Danish Air Quality Monitoring Programme (LMP IV) has been revised in accordance with the Framework Directive and the first three daughter directives of SO2, NOx/NO2, PM10, lead, benzene, CO and ozone. PM10 samplers are under installation and the installation will be completed during 2002...

  11. VAM programme 14

    Energy Technology Data Exchange (ETDEWEB)

    Youngman, Michael [National Radiological Protection Board, Chilton (United Kingdom)

    1995-05-01

    Since 1988, the Department of Trade and Industry (DTI) has supported a Valid Analytical Measurement (VAM) initiative. VAM programming 14 is concerned with sampling and measurement of aerosols and particulates in the gas phase. The programme of work is summarised here. (author).

  12. En model for programmer

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak

    Dette undervisningsmateriale beskriver en model for, hvordan programmer er opbygget. Materialet er skrevet til brug i det gymnasiale forsøgsfag Informationsteknologi. Seneste version af dette undervisningsmateriale kan findes på http:// www.imhotep.dk. Tak til Elisabeth Husum for en kritisk...

  13. CD11c+ dendritic cells and B cells contribute to the tumoricidal activity of anti-DR5 antibody therapy in established tumors.

    Science.gov (United States)

    Haynes, Nicole M; Hawkins, Edwin D; Li, Ming; McLaughlin, Nicole M; Hämmerling, Günter J; Schwendener, Reto; Winoto, Astar; Wensky, Allen; Yagita, Hideo; Takeda, Kazuyoshi; Kershaw, Michael H; Darcy, Phillip K; Smyth, Mark J

    2010-07-01

    The selective targeting of the tumor-associated death-inducing receptors DR4 and DR5 with agonistic mAbs has demonstrated preclinical and clinical antitumor activity. However, the cellular and molecular mechanisms contributing to this efficacy remain poorly understood. In this study, using the first described C57BL/6 (B6) TRAIL-sensitive experimental tumor models, we have characterized the innate and adaptive immune components involved in the primary rejection phase of an anti-mouse DR5 (mDR5) mAb, MD5-1 in established MC38 colon adenocarcinomas. FcR mediated cross-linking of MD5-1 significantly inhibited the growth of MC38 colon adenocarcinomas through the induction of TRAIL-R-dependent tumor cell apoptosis. The loss of host DR5, TRAIL, perforin, FasL, or TNF did not compromise anti-DR5 therapy in vivo. By contrast, anti-DR5 therapy was completely abrogated in mice deficient of B cells or CD11c(+) dendritic cells (DCs), providing the first direct evidence that these cells play a critical role. Importantly, the requirement for an intact B cell compartment for optimal anti-DR5 antitumor efficacy was also observed in established AT-3 mammary tumors. Interestingly, MD5-1-mediated apoptosis as measured by early TUNEL activity was completely lost in B cell-deficient microMT mice, but intact in mice deficient in CD11c(+) DCs. Overall, these data show that Ab-mediated targeting of DR5 triggers tumor cell apoptosis in established tumors in a B cell-dependent manner and that CD11c(+) DCs make a critical downstream contribution to anti-DR5 antitumor activity.

  14. EdAl-2 (Educació en Alimentació) programme: reproducibility of a cluster randomised, interventional, primary-school-based study to induce healthier lifestyle activities in children

    OpenAIRE

    2014-01-01

    Objectives To assess the reproducibility of an educational intervention EdAl-2 ( Educació en Alimentació) programme in ‘Terres de l'Ebre’ (Spain), over 22 months, to improve lifestyles, including diet and physical activity (PA). Design Reproduction of a cluster randomised controlled trial. Setting Two semi-rural town-group primary-school clusters were randomly assigned to the intervention or control group. Participants Pupils (n=690) of whom 320 constituted the intervention group (1 cluster) ...

  15. Evaluating the effectiveness of a schools-based programme to promote exercise self-efficacy in children and young people with risk factors for obesity: Steps to active kids (STAK

    Directory of Open Access Journals (Sweden)

    Yang Min

    2011-10-01

    Full Text Available Abstract Background Low levels of physical activity in children have been linked to an increased risk of obesity, but many children lack confidence in relation to exercise (exercise self-efficacy. Factors which can impact on confidence include a chronic health condition such as asthma, poor motor skills and being overweight. Increasing levels of physical activity have obvious benefits for children with asthma and children who are overweight, but few activity interventions with children specifically target children with low exercise self-efficacy (ESE. This study aims to evaluate the efficacy and feasibility of a schools-based activity programme suitable for children with risk factors for adult obesity, including asthma, overweight and low exercise self-efficacy. Methods/Design A clustered (at the level of school RCT will be used to compare a targeted, 10 week, stepped activity programme (activity diary, dance DVD, circuit-training and motivational interviewing designed to promote ESE. We will recruit 20 primary schools to participate in the intervention and 9-11 year old children will be screened for low levels of ESE, asthma and overweight. In order to provide sufficient power to detect a difference in primary outcomes (Body Mass Index-BMI & ESE at 12 month follow-up between children in the intervention schools and control schools, the target sample size is 396. Assessments of BMI, ESE, waist circumference, peak flow, activity levels and emotional and behavioural difficulties will be made at baseline, 4 months and 12 month follow-up. Discussion We aim to increase ESE and levels of physical activity in children with risk factors for adult obesity. The outcomes of this study will inform policy makers about the feasibility, acceptability and effectiveness of delivering targeted health interventions within a school setting. Trial Registration ISRCTN Register no. ISRCTN12650001

  16. Evaluating the effectiveness of a schools-based programme to promote exercise self-efficacy in children and young people with risk factors for obesity: Steps to active kids (STAK)

    Science.gov (United States)

    2011-01-01

    Background Low levels of physical activity in children have been linked to an increased risk of obesity, but many children lack confidence in relation to exercise (exercise self-efficacy). Factors which can impact on confidence include a chronic health condition such as asthma, poor motor skills and being overweight. Increasing levels of physical activity have obvious benefits for children with asthma and children who are overweight, but few activity interventions with children specifically target children with low exercise self-efficacy (ESE). This study aims to evaluate the efficacy and feasibility of a schools-based activity programme suitable for children with risk factors for adult obesity, including asthma, overweight and low exercise self-efficacy. Methods/Design A clustered (at the level of school) RCT will be used to compare a targeted, 10 week, stepped activity programme (activity diary, dance DVD, circuit-training and motivational interviewing) designed to promote ESE. We will recruit 20 primary schools to participate in the intervention and 9-11 year old children will be screened for low levels of ESE, asthma and overweight. In order to provide sufficient power to detect a difference in primary outcomes (Body Mass Index-BMI & ESE at 12 month follow-up) between children in the intervention schools and control schools, the target sample size is 396. Assessments of BMI, ESE, waist circumference, peak flow, activity levels and emotional and behavioural difficulties will be made at baseline, 4 months and 12 month follow-up. Discussion We aim to increase ESE and levels of physical activity in children with risk factors for adult obesity. The outcomes of this study will inform policy makers about the feasibility, acceptability and effectiveness of delivering targeted health interventions within a school setting. Trial Registration ISRCTN Register no. ISRCTN12650001 PMID:22029547

  17. Evaluating the effectiveness of a schools-based programme to promote exercise self-efficacy in children and young people with risk factors for obesity: steps to active kids (STAK).

    Science.gov (United States)

    Glazebrook, Cris; Batty, Martin J; Mullan, Nivette; Macdonald, Ian; Nathan, Dilip; Sayal, Kapil; Smyth, Alan; Yang, Min; Guo, Boliang; Hollis, Chris

    2011-10-26

    Low levels of physical activity in children have been linked to an increased risk of obesity, but many children lack confidence in relation to exercise (exercise self-efficacy). Factors which can impact on confidence include a chronic health condition such as asthma, poor motor skills and being overweight. Increasing levels of physical activity have obvious benefits for children with asthma and children who are overweight, but few activity interventions with children specifically target children with low exercise self-efficacy (ESE). This study aims to evaluate the efficacy and feasibility of a schools-based activity programme suitable for children with risk factors for adult obesity, including asthma, overweight and low exercise self-efficacy. A clustered (at the level of school) RCT will be used to compare a targeted, 10 week, stepped activity programme (activity diary, dance DVD, circuit-training and motivational interviewing) designed to promote ESE. We will recruit 20 primary schools to participate in the intervention and 9-11 year old children will be screened for low levels of ESE, asthma and overweight. In order to provide sufficient power to detect a difference in primary outcomes (Body Mass Index-BMI & ESE at 12 month follow-up) between children in the intervention schools and control schools, the target sample size is 396. Assessments of BMI, ESE, waist circumference, peak flow, activity levels and emotional and behavioural difficulties will be made at baseline, 4 months and 12 month follow-up. We aim to increase ESE and levels of physical activity in children with risk factors for adult obesity. The outcomes of this study will inform policy makers about the feasibility, acceptability and effectiveness of delivering targeted health interventions within a school setting. ISRCTN Register no. ISRCTN12650001.

  18. Framework Programmable Platform for the Advanced Software Development Workstation (FPP/ASDW). Demonstration framework document. Volume 1: Concepts and activity descriptions

    Science.gov (United States)

    Mayer, Richard J.; Blinn, Thomas M.; Dewitte, Paul S.; Crump, John W.; Ackley, Keith A.

    1992-01-01

    The Framework Programmable Software Development Platform (FPP) is a project aimed at effectively combining tool and data integration mechanisms with a model of the software development process to provide an intelligent integrated software development environment. Guided by the model, this system development framework will take advantage of an integrated operating environment to automate effectively the management of the software development process so that costly mistakes during the development phase can be eliminated. The Advanced Software Development Workstation (ASDW) program is conducting research into development of advanced technologies for Computer Aided Software Engineering (CASE).

  19. The 'Walking for Wellbeing in the West' randomised controlled trial of a pedometer-based walking programme in combination with physical activity consultation with 12 month follow-up: rationale and study design

    Directory of Open Access Journals (Sweden)

    Ogilvie David

    2008-07-01

    Full Text Available Abstract Background Scotland has a policy aimed at increasing physical activity levels in the population, but evidence on how to achieve this is still developing. Studies that focus on encouraging real world participants to start physical activity in their settings are needed. The Walking for Well-being in the West study was designed to assess the effectiveness of a pedometer-based walking programme in combination with physical activity consultation. The study was multi-disciplinary and based in the community. Walking for Well-being in the West investigated whether Scottish men and women, who were not achieving the current physical activity recommendation, increased and maintained walking behaviour over a 12 month period. This paper outlines the rationale and design of this innovative and pragmatic study. Methods Participants were randomised into two groups: Group 1: Intervention (pedometer-based walking programme combined with a series of physical activity consultations; Group 2: Waiting list control for 12 weeks (followed by minimal pedometer-based intervention. Physical activity (primary outcome was measured using pedometer step counts (7 day and the International Physical Activity Questionnaire (long version. Psychological processes were measured using questionnaires relating to the Transtheoretical Model of Behaviour Change, mood (Positive and Negative Affect Schedule and quality of life (Euroqol EQ-5D instrument. Physiological measures included anthropometric and metabolic outcomes. Environmental influences were assessed subjectively (Neighbourhood Quality of Life Survey and objectively (neighbourhood audit tool and GIS mapping. The qualitative evaluation employed observation, semi-structured interviews and focus groups. A supplementary study undertook an economic evaluation. Discussion Data analysis is on-going. Walking for Well-being in the West will demonstrate if a pedometer based walking programme, in combination with physical

  20. Development of human resources for Indian nuclear power programme

    Indian Academy of Sciences (India)

    R B Grover; R R Puri

    2013-10-01

    The continuing research and development on nuclear technology by research establishments in the country and maturing of Indian industry have brought the nuclear energy programme in India to a stage where it is poised to take a quantum leap forward. The vision of expansion of nuclear power also requires a wellstructured specialized human resource development programme. This paper discusses the requirements of the human resource development programme for nuclear energy, the challenges in the way of its realization, its national and international status and traces the history of nuclear education in the country. It brings out the linkage of human resource development programme with the nuclear energy programme in the country. It also describes the initiatives by the university system in the area of nuclear education and support provided by the Department of Atomic Energy to the university system by way of extra-mural funding and by providing access to research facilities.

  1. The INTEGRAL Core Observing Programme

    DEFF Research Database (Denmark)

    Winkler, C.; Gehrels, N.; Lund, Niels

    1999-01-01

    The Core Programme of the INTEGRAL mission is defined as the portion of the scientific programme covering the guaranteed time observations for the INTEGRAL Science Working Team. This paper describes the current status of the Core Programme preparations and summarizes the key elements...

  2. The INTEGRAL Core Observing Programme

    DEFF Research Database (Denmark)

    Winkler, C.; Gehrels, N.; Lund, Niels

    1999-01-01

    The Core Programme of the INTEGRAL mission is defined as the portion of the scientific programme covering the guaranteed time observations for the INTEGRAL Science Working Team. This paper describes the current status of the Core Programme preparations and summarizes the key elements...

  3. International Cooperative Programme for Assessment and Monitoring of Acidification of Rivers and Lakes. Programme Manual

    Energy Technology Data Exchange (ETDEWEB)

    Bowman, J.; Forsius, M.; Jeffries, D. [and others

    1996-12-31

    The International Cooperative Programme for Assessment of Acidification of Rivers and lakes (ICP Waters) was established in 1985 by the UN/ECE Executive Body for the Convention of Long-Range Transboundary Air Pollution. Achieving the programme objectives requires that both the temporally intensive and regionally extensive data are collected on a continuing basis. To guide the development and harmonization of the various national contributions, a manual was worked out. The present report is an expanded and consolidated revision of that manual. 33 refs., 3 tabs.

  4. State Safety Programme and State Safety Plan - Part one – State Safety Programme structure

    Directory of Open Access Journals (Sweden)

    Peter Vittek

    2014-11-01

    Full Text Available State Safety Programme and plan are considered the main instruments in safety management. In that matter, this paper focuses on their description and simultaneously tries to clarify a need and significance of their establishment and implementation within respective state. All elements, defined in ICAO doc. 9859 as State Safety Programme (SSP fundamentals, are separately described. These elements are divided into four groups, further detailed in individual chapters – State Safety Policy and objectives, State Safety Risk management, State safety assurance, State Safety Promotion.

  5. Economic viability of new launched school lunch programmes

    DEFF Research Database (Denmark)

    Jensen, Jørgen Dejgård; Smed, Sinne; Mørkbak, Morten Raun

    2013-01-01

    activities related to the schools’ support and the users’ feeling of ownership, as well as internal professionalism and leadership in the implementation of the school lunch programme are important for the viability of the programme. Strong performance on the latter factors might to some extent compensate...

  6. The VIDA Programme

    DEFF Research Database (Denmark)

    Jensen, Bente; Iannone, Rosa Lisa

    and Innovation’ within the project ‘Curriculum Quality Analysis and Impact Review of European Education and Care’ (CARE). The programme at the centre of this case builds on theory drawn from research on child development, social disadvantage related to issues of social inequality, and research on organisational...... learning and innovation. The latter field has tended to focus primarily on technological innovation, leaving socially-driven innovation in the shade (Dawson & Daniel, 2010). Here, in the field of early childhood education and care (ECEC), we draw on Dawson and Daniel’s (ibid., p. 10) definition...... programme period (2010-2013) and beyond?; 2) What is the impact of the VIDA approach to professional development on i) educators’ practices regarding high quality ECEC (output), ii) child outcomes (outcome), and iii) improved practice at the municipal level (impact in a broader sense)?; and 3) Which factors...

  7. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    Main Auditorium bldg. 500 Date Time Lecturer Title Monday 13 August 9:15 10:15 11:15 Student Session (3/3) Course Review Course Review Tuesday 14 August 16:00 Poster Session Further information can be obtained on the web at the following URL: Summer Student Lecture ProgrammeSummer Student Lectures are available at: http://agenda.cern.ch/SSLP2001

  8. NSF announces diversity programme

    Science.gov (United States)

    Kruesi, Liz

    2016-04-01

    The US National Science Foundation (NSF) has initiated a new funding programme that will create schemes to increase diversity in science, technology, engineering and mathematics (STEM). The initiative - Inclusion across the Nation of Communities of Learners of Underrepresented Discoverers in Engineering and Science (INCLUDES) - aims to increase the participation of women, those with a low socioeconomic status, people with disabilities and those from minority racial backgrounds.

  9. Programmable mechanical metamaterials.

    Science.gov (United States)

    Florijn, Bastiaan; Coulais, Corentin; van Hecke, Martin

    2014-10-24

    We create mechanical metamaterials whose response to uniaxial compression can be programmed by lateral confinement, allowing monotonic, nonmonotonic, and hysteretic behavior. These functionalities arise from a broken rotational symmetry which causes highly nonlinear coupling of deformations along the two primary axes of these metamaterials. We introduce a soft mechanism model which captures the programmable mechanics, and outline a general design strategy for confined mechanical metamaterials. Finally, we show how inhomogeneous confinement can be explored to create multistability and giant hysteresis.

  10. Punch card programmable microfluidics.

    Science.gov (United States)

    Korir, George; Prakash, Manu

    2015-01-01

    Small volume fluid handling in single and multiphase microfluidics provides a promising strategy for efficient bio-chemical assays, low-cost point-of-care diagnostics and new approaches to scientific discoveries. However multiple barriers exist towards low-cost field deployment of programmable microfluidics. Incorporating multiple pumps, mixers and discrete valve based control of nanoliter fluids and droplets in an integrated, programmable manner without additional required external components has remained elusive. Combining the idea of punch card programming with arbitrary fluid control, here we describe a self-contained, hand-crank powered, multiplex and robust programmable microfluidic platform. A paper tape encodes information as a series of punched holes. A mechanical reader/actuator reads these paper tapes and correspondingly executes operations onto a microfluidic chip coupled to the platform in a plug-and-play fashion. Enabled by the complexity of codes that can be represented by a series of holes in punched paper tapes, we demonstrate independent control of 15 on-chip pumps with enhanced mixing, normally-closed valves and a novel on-demand impact-based droplet generator. We demonstrate robustness of operation by encoding a string of characters representing the word "PUNCHCARD MICROFLUIDICS" using the droplet generator. Multiplexing is demonstrated by implementing an example colorimetric water quality assays for pH, ammonia, nitrite and nitrate content in different water samples. With its portable and robust design, low cost and ease-of-use, we envision punch card programmable microfluidics will bring complex control of microfluidic chips into field-based applications in low-resource settings and in the hands of children around the world.

  11. Punch card programmable microfluidics.

    Directory of Open Access Journals (Sweden)

    George Korir

    Full Text Available Small volume fluid handling in single and multiphase microfluidics provides a promising strategy for efficient bio-chemical assays, low-cost point-of-care diagnostics and new approaches to scientific discoveries. However multiple barriers exist towards low-cost field deployment of programmable microfluidics. Incorporating multiple pumps, mixers and discrete valve based control of nanoliter fluids and droplets in an integrated, programmable manner without additional required external components has remained elusive. Combining the idea of punch card programming with arbitrary fluid control, here we describe a self-contained, hand-crank powered, multiplex and robust programmable microfluidic platform. A paper tape encodes information as a series of punched holes. A mechanical reader/actuator reads these paper tapes and correspondingly executes operations onto a microfluidic chip coupled to the platform in a plug-and-play fashion. Enabled by the complexity of codes that can be represented by a series of holes in punched paper tapes, we demonstrate independent control of 15 on-chip pumps with enhanced mixing, normally-closed valves and a novel on-demand impact-based droplet generator. We demonstrate robustness of operation by encoding a string of characters representing the word "PUNCHCARD MICROFLUIDICS" using the droplet generator. Multiplexing is demonstrated by implementing an example colorimetric water quality assays for pH, ammonia, nitrite and nitrate content in different water samples. With its portable and robust design, low cost and ease-of-use, we envision punch card programmable microfluidics will bring complex control of microfluidic chips into field-based applications in low-resource settings and in the hands of children around the world.

  12. The Mathematica programmer

    CERN Document Server

    Maeder, Roman E

    1994-01-01

    The Mathematica Programmer covers the fundamental programming paradigms and applications of programming languages. This book is organized into two parts encompassing 10 chapters. Part 1 begins with an overview of the programming paradigms. This part also treats abstract data types, polymorphism and message passing, object-oriented programming, and relational databases. Part 2 looks into the practical aspects of programming languages, including in lists and power series, fractal curves, and minimal surfaces.This book will prove useful to mathematicians and computer scientists.

  13. Programmable Quantitative DNA Nanothermometers.

    Science.gov (United States)

    Gareau, David; Desrosiers, Arnaud; Vallée-Bélisle, Alexis

    2016-07-13

    Developing molecules, switches, probes or nanomaterials that are able to respond to specific temperature changes should prove of utility for several applications in nanotechnology. Here, we describe bioinspired strategies to design DNA thermoswitches with programmable linear response ranges that can provide either a precise ultrasensitive response over a desired, small temperature interval (±0.05 °C) or an extended linear response over a wide temperature range (e.g., from 25 to 90 °C). Using structural modifications or inexpensive DNA stabilizers, we show that we can tune the transition midpoints of DNA thermometers from 30 to 85 °C. Using multimeric switch architectures, we are able to create ultrasensitive thermometers that display large quantitative fluorescence gains within small temperature variation (e.g., > 700% over 10 °C). Using a combination of thermoswitches of different stabilities or a mix of stabilizers of various strengths, we can create extended thermometers that respond linearly up to 50 °C in temperature range. Here, we demonstrate the reversibility, robustness, and efficiency of these programmable DNA thermometers by monitoring temperature change inside individual wells during polymerase chain reactions. We discuss the potential applications of these programmable DNA thermoswitches in various nanotechnology fields including cell imaging, nanofluidics, nanomedecine, nanoelectronics, nanomaterial, and synthetic biology.

  14. A new video programme

    CERN Multimedia

    CERN video productions

    2011-01-01

    "What's new @ CERN?", a new monthly video programme, will be broadcast on the Monday of every month on webcast.cern.ch. Aimed at the general public, the programme will cover the latest CERN news, with guests and explanatory features. Tune in on Monday 3 October at 4 pm (CET) to see the programme in English, and then at 4:20 pm (CET) for the French version.   var flash_video_player=get_video_player_path(); insert_player_for_external('Video/Public/Movies/2011/CERN-MOVIE-2011-129/CERN-MOVIE-2011-129-0753-kbps-640x360-25-fps-audio-64-kbps-44-kHz-stereo', 'mms://mediastream.cern.ch/MediaArchive/Video/Public/Movies/2011/CERN-MOVIE-2011-129/CERN-MOVIE-2011-129-Multirate-200-to-753-kbps-640x360-25-fps.wmv', 'false', 480, 360, 'https://mediastream.cern.ch/MediaArchive/Video/Public/Movies/2011/CERN-MOVIE-2011-129/CERN-MOVIE-2011-129-posterframe-640x360-at-10-percent.jpg', '1383406', true, 'Video/Public/Movies/2011/CERN-MOVIE-2011-129/CERN-MOVIE-2011-129-0600-kbps-maxH-360-25-fps-...

  15. 2001 - 2002 ACADEMIC TRAINING PROGRAMME

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    1ST TERM 1ST OCTOBER - 23 NOVEMBER 2001 LECTURE SERIES FOR POSTGRADUATE STUDENTS The Autumn term of the Academic Training Programme is about to start. As usual, the first term includes lectures primarily dedicated to Post-graduate students. These are meant to help students complement the courses available from their home Universities with lectures on topics close to CERN activities. The lectures are nevertheless open to all CERN staff, and in particular to young Fellows. This year's series include courses on Accelerator Physics, on Field Theory, and on Symmetry Breaking Phenomena in Physics. The course on Accelerators by Dr. Wilson has been a regular feature on the Academic Training programme for many previous editions. This year, the course will be updated to include new sections on Colliders and on future facilities such as the Neutrino Factory. A good introduction to this very successful course can be found in the previous version of these lectures, available from the Web Lecture Archive Project: http://w...

  16. Sellafield Decommissioning Programme - Update and Lessons Learned

    Energy Technology Data Exchange (ETDEWEB)

    Lutwyche, P. R.; Challinor, S. F.

    2003-02-24

    The Sellafield site in North West England has over 240 active facilities covering the full nuclear cycle from fuel manufacture through generation, reprocessing and waste treatment. The Sellafield decommissioning programme was formally initiated in the mid 1980s though several plants had been decommissioned prior to this primarily to create space for other plants. Since the initiation of the programme 7 plants have been completely decommissioned, significant progress has been made in a further 16 and a total of 56 major project phases have been completed. This programme update will explain the decommissioning arrangements and strategies and illustrate the progress made on a number of the plants including the Windscale Pile Chimneys, the first reprocessing plan and plutonium plants. These present a range of different challenges and requiring approaches from fully hands on to fully remote. Some of the key lessons learned will be highlighted.

  17. A job-related self-image enhancement programme

    OpenAIRE

    2012-01-01

    D.Litt. et Phil. This research focuses on self-concept improvement for adults. A self-image enhancement programme has been developed and its impact tested with regard to shortand medium term developments. Various training approaches have been compared to establish whether massed or spaced sessions training is more effective, and whether individual follow-up after the programme is of advantage. Self-image enhancement is seen as central to a person's functioning and psychological well-being....

  18. Creating meaningful business continuity management programme metrics.

    Science.gov (United States)

    Strong, Brian

    2010-11-01

    The popular axiom, 'what gets measured gets done', is often applied in the quality management and continuous improvement disciplines. This truism is also useful to business continuity practitioners as they continually strive to prove the value of their organisation's investment in a business continuity management (BCM) programme. BCM practitioners must also remain relevant to their organisations as executives focus on the bottom line and maintaining stakeholder confidence. It seems that executives always find a way, whether in a hallway or elevator, to ask BCM professionals about the company's level of readiness. When asked, they must be ready with an informed response. The establishment of a process to measure business continuity programme performance and organisational readiness has emerged as a key component of US Department of Homeland Security 'Voluntary Private Sector Preparedness (PS-Prep) Program' standards where the overarching goal is to improve private sector preparedness for disasters and emergencies. The purpose of this paper is two-fold: to introduce continuity professionals to best practices that should be considered when developing a BCM metrics programme as well as providing a case study of how a large health insurance company researched, developed and implemented a process to measure BCM programme performance and company readiness.

  19. Report for Energy Centre Denmark's OPET activities 1997-1998; Rapport over Energicenter Danmarks OPET aktiviteter 1997-98

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The report presents OPET activities of Energy Center during the period 1997-1998. The EU Commission established the OPET network in preparation for spreading information about innovative energy forms and presentation of EU's FoU programmes with weight on the THERMIE programme. (EHS)

  20. Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer

    Science.gov (United States)

    Zhang, Yaqing; Velez-Delgado, Ashley; Mathew, Esha; Li, Dongjun; Mendez, Flor M; Flannagan, Kevin; Rhim, Andrew D; Simeone, Diane M; Beatty, Gregory L; Pasca di Magliano, Marina

    2017-01-01

    Background Pancreatic cancer is characterised by the accumulation of a fibro-inflammatory stroma. Within this stromal reaction, myeloid cells are a predominant population. Distinct myeloid subsets have been correlated with tumour promotion and unmasking of anti-tumour immunity. Objective The goal of this study was to determine the effect of myeloid cell depletion on the onset and progression of pancreatic cancer and to understand the relationship between myeloid cells and T cell-mediated immunity within the pancreatic cancer microenvironment. Methods Primary mouse pancreatic cancer cells were transplanted into CD11b-diphtheria toxin receptor (DTR) mice. Alternatively, the iKras* mouse model of pancreatic cancer was crossed into CD11b-DTR mice. CD11b+ cells (mostly myeloid cell population) were depleted by diphtheria toxin treatment during tumour initiation or in established tumours. Results Depletion of myeloid cells prevented KrasG12D-driven pancreatic cancer initiation. In pre-established tumours, myeloid cell depletion arrested tumour growth and in some cases, induced tumour regressions that were dependent on CD8+ T cells. We found that myeloid cells inhibited CD8+ T-cell anti-tumour activity by inducing the expression of programmed cell death-ligand 1 (PD-L1) in tumour cells in an epidermal growth factor receptor (EGFR)/mitogen-activated protein kinases (MAPK)-dependent manner. Conclusion Our results show that myeloid cells support immune evasion in pancreatic cancer through EGFR/MAPK-dependent regulation of PD-L1 expression on tumour cells. Derailing this crosstalk between myeloid cells and tumour cells is sufficient to restore anti-tumour immunity mediated by CD8+ T cells, a finding with implications for the design of immune therapies for pancreatic cancer. PMID:27402485

  1. Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer.

    Science.gov (United States)

    Zhang, Yaqing; Velez-Delgado, Ashley; Mathew, Esha; Li, Dongjun; Mendez, Flor M; Flannagan, Kevin; Rhim, Andrew D; Simeone, Diane M; Beatty, Gregory L; Pasca di Magliano, Marina

    2017-01-01

    Pancreatic cancer is characterised by the accumulation of a fibro-inflammatory stroma. Within this stromal reaction, myeloid cells are a predominant population. Distinct myeloid subsets have been correlated with tumour promotion and unmasking of anti-tumour immunity. The goal of this study was to determine the effect of myeloid cell depletion on the onset and progression of pancreatic cancer and to understand the relationship between myeloid cells and T cell-mediated immunity within the pancreatic cancer microenvironment. Primary mouse pancreatic cancer cells were transplanted into CD11b-diphtheria toxin receptor (DTR) mice. Alternatively, the iKras* mouse model of pancreatic cancer was crossed into CD11b-DTR mice. CD11b(+) cells (mostly myeloid cell population) were depleted by diphtheria toxin treatment during tumour initiation or in established tumours. Depletion of myeloid cells prevented Kras(G12D)-driven pancreatic cancer initiation. In pre-established tumours, myeloid cell depletion arrested tumour growth and in some cases, induced tumour regressions that were dependent on CD8(+) T cells. We found that myeloid cells inhibited CD8(+) T-cell anti-tumour activity by inducing the expression of programmed cell death-ligand 1 (PD-L1) in tumour cells in an epidermal growth factor receptor (EGFR)/mitogen-activated protein kinases (MAPK)-dependent manner. Our results show that myeloid cells support immune evasion in pancreatic cancer through EGFR/MAPK-dependent regulation of PD-L1 expression on tumour cells. Derailing this crosstalk between myeloid cells and tumour cells is sufficient to restore anti-tumour immunity mediated by CD8(+) T cells, a finding with implications for the design of immune therapies for pancreatic cancer. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  2. Flexible programmable logic module

    Energy Technology Data Exchange (ETDEWEB)

    Robertson, Perry J. (Albuquerque, NM); Hutchinson, Robert L. (Albuquerque, NM); Pierson, Lyndon G. (Albuquerque, NM)

    2001-01-01

    The circuit module of this invention is a VME board containing a plurality of programmable logic devices (PLDs), a controlled impedance clock tree, and interconnecting buses. The PLDs are arranged to permit systolic processing of a problem by offering wide data buses and a plurality of processing nodes. The board contains a clock reference and clock distribution tree that can drive each of the PLDs with two critically timed clock references. External clock references can be used to drive additional circuit modules all operating from the same synchronous clock reference.

  3. The ONTARGET trial programme

    DEFF Research Database (Denmark)

    Unger, Thomas; Kintscher, Ulrich; Kappert, Kai;

    2009-01-01

    The ONTARGET trial programme tested the effects of the angiotensin AT1 receptor blocker (ARB), telmisartan, alone or in combination with the angiotensin converting enzyme (ACE) inhibitor, ramipril, in more than 25.000 patients at high cardiovascular risk including diabetes on a combined endpoint ....... Telmisartan thus proved to be the first and so far the only representative of the ARB class that can be used as an alternative to the "gold standard" ACE-inhibitor, ramipril, in patients at high cardiovascular risk with or without hypertension. © 2009 Bentham Science Publishers Ltd....

  4. Programmable pulse generator

    CERN Document Server

    Xue Zhi Hua; Duan Xiao Hui

    2002-01-01

    The author introduces the design of programmable pulse generator that is based on a micro-controller and controlled by RS232 interface of personal computer. The whole system has good stability. The pulse generator can produce TTL pulse and analog pulse. The pulse frequency can be selected by EPLD. The voltage amplitude and pulse width of analog pulse can be adjusted by analog switches and digitally-controlled potentiometers. The software development tools of computer is National Instruments LabView5.1. The front panel of this virtual instrumentation is intuitive and easy-to-use. Parameters can be selected and changed conveniently by knob and slide

  5. Binary mask programmable hologram.

    Science.gov (United States)

    Tsang, P W M; Poon, T-C; Zhou, Changhe; Cheung, K W K

    2012-11-19

    We report, for the first time, the concept and generation of a novel Fresnel hologram called the digital binary mask programmable hologram (BMPH). A BMPH is comprised of a static, high resolution binary grating that is overlaid with a lower resolution binary mask. The reconstructed image of the BMPH can be programmed to approximate a target image (including both intensity and depth information) by configuring the pattern of the binary mask with a simple genetic algorithm (SGA). As the low resolution binary mask can be realized with less stringent display technology, our method enables the development of simple and economical holographic video display.

  6. RDandD Programme 2010. Programme for research, development and demonstration of methods for the management and disposal of nuclear waste

    Energy Technology Data Exchange (ETDEWEB)

    2010-09-15

    RDandD Programme 2010 presents SKB's plans for research, development and demonstration during the period 2011-2016. SKB's activities are divided into two main areas: the programme for low- and intermediate-level waste (the LILW Programme) and the Nuclear Fuel Programme. Operation of the existing facilities takes place within the Operational Process. RDandD Programme 2010 consists of five parts: Part I Overall plan of action Part II The LILW Programme Part III The Nuclear Fuel Programme Part IV Research for assessment of long-term safety Part V Social science research RDandD Programme 2007 was mainly focused on development of technology to realize the final repository for spent nuclear fuel. The efforts described were aimed at gaining a greater knowledge of long-term safety and compiling technical supporting documentation for applications under the Nuclear Activities Act for the final repository for spent nuclear fuel and under the Environmental Code for the final repository system. Many important results from these efforts are reported in this programme. The integrated account of the results will be presented in applications submitted in early 2011. The regulatory review of RDandD Programme 2007 and its supplement called for clarifications of plans and programmes for the final repository for short-lived radioactive waste, SFR, and the final repository for long-lived waste, SFL. This RDandD Programme describes these plans more clearly

  7. [Immunization Programme and Coverage against Measles and Rubella in Spain. Challenges for Achieving their Elimination].

    Science.gov (United States)

    Limia Sánchez, Aurora; Molina Olivas, Marta

    2015-01-01

    The World Health Organization had established the achievement and sustainability of very high coverage with two doses of vaccine against measles and at least one against rubella as one of the key strategies for the elimination of both measles and rubella. The current immunization programme in Spain includes the immunization with two doses of combined vaccine against measles, mumps and rubella at 12 months and 3-4 years of age. Since 2000 coverage with first dose is over the target of 95% but the coverage with the second dose remains between 90 and 95%. In 2014, at subnational level three regions had coverage below the objective and only eight regions achieved the objective for the second dose. The challenges and some activities to strengthen the immunization programme in order to achieve the elimination of measles and rubella are discussed.

  8. Critical interactions between Global Fund-supported programmes and health systems: a case study in Papua New Guinea.

    Science.gov (United States)

    Rudge, James W; Phuanakoonon, Suparat; Nema, K Henry; Mounier-Jack, Sandra; Coker, Richard

    2010-11-01

    In Papua New Guinea, investment by the Global Fund to Fight AIDS, Tuberculosis and Malaria (the Global Fund) has played an important role in scaling up the response to HIV and tuberculosis (TB). As part of a series of case studies on how Global Fund-supported programmes interact with national health systems, we assessed the nature and extent of integration of the Global Fund portfolios within the national HIV and TB programmes, the integration of the HIV and TB programmes within the general health system, and system-wide effects of Global Fund support in Papua New Guinea. The study relied on a literature review and 30 interviews with key stakeholders using the Systemic Rapid Assessment Toolkit and thematic analysis. Global Fund-supported activities were found to be largely integrated, or at least coordinated, with the national HIV and TB programmes. However, this has reinforced the vertical nature of these programmes with respect to the general health system, with parallel systems established to meet the demands of programme scale-up and the performance-based nature of Global Fund investment in the weak health system context of Papua New Guinea. The more parallel functions include monitoring and evaluation, and procurement and supply chain systems, while human resources and infrastructure for service delivery are increasingly integrated at more local levels. Positive synergies of Global Fund support include engagement of civil-society partners, and a reliable supply of high-quality drugs which may have increased patient confidence in the health system. However, the severely limited and overburdened pool of human resources has been skewed towards the three diseases, both at management and service delivery levels. There is also concern surrounding the sustainability of the disease programmes, given their dependence on donors. Increasing Global Fund attention towards health system strengthening was viewed positively, but should acknowledge that system changes are slow

  9. Establishing biomass heating in the UK: phase 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    The Biomass Heat Working Group, first set up in 1995, was taken on by British BioGen in 1996. Over the summer of 1996 British BioGen, supported by DTI, worked with the group to produce 'A Strategy to Develop the UK Market for Biomass Heating Installations'. In the spring of 1997 British BioGen agreed a two-year programme with ETSU (for the DTI) to 'Establish Biomass Heating in the UK'. The DTI's New and Renewable Energy Programme has supported this two-year programme which aims to bring together industry stakeholders and assist in the development of a significant biomass heat market in the UK. Overall we believe the project has been successful in its aim to increase the volume of biomass heating enquiries and enable greater use of the industry 'knowledge base'. Throughout the duration of the project a number of new biomass heating systems have been installed, including Shenstone Lodge School, Boughton Pumping Station and Elvendon Priory. In addition, an efficient system of information exchange has been established for customers and industry. British BioGen believe that the benefits of this system will be a crucial factor in achieving bioenergy industry targets of 2MWt for domestic heating, 2MWt for industrial and commercial heating and 2MWt for CHP by the end of 2001. The remainder of this summary offers highlights of the activities undertaken within the project, outlines the conclusions of the project and makes brief recommendations for further actions to assist the further deployment of biomass heating in the UK. (author)

  10. The Transparency Programme of the Swedish National Council for Nuclear Waste. A Status Report

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Kjell (Karita Research AB, Taeby (Sweden)), E-Mail: kjell.andersson@karita.se

    2009-12-15

    In this paper the activities of the Transparency Programme of the Swedish National Council for Nuclear Waste have been explored. Comparisons have been made with other activities using the same transparency approach and observations made from different reports that deal with the programme or parts of it have been taken into account. Obviously, to make firm conclusions to what extent the aims of the Transparency Programme have been achieved a formal review should be done. It seems evident however that the programme has vitalized the overall dialogue about the Swedish nuclear waste management programme and that the hearings held have raised the awareness about issues that have been dealt with such as value-laden aspects of disposals methods, feasibility of certain alternatives, the need for clarification of how regulatory criteria can be applied and the use of research on governance processes. Stakeholders seem to have appreciated the overall organization and the stretching that took place during the hearings held. For possible future activities, the observations made about the antagonism between certain parties which has existed since a long time ago and the common language and culture need to be taken into account. The core problem, however, is to reach out to the political decision makers at the national level, especially since the time distance between hearings held so far and critical government decisions is at least six years which put a high demand on the reporting system. Taking the experiences from other transparency projects into account, the Council might consider the possibility to establish a reference group with participation from different stakeholders and politicians who could have a role for conveying results to wider groups. One observer has concluded that the reporting from the Transparency Programme should be open in the sense that it should not make conclusions on the issues as such (e.g. if a certain disposal method is to prefer or not). Instead

  11. A Method of Hepatocyte Extraction Conjugated with HPLC is Established for Screening Potential Active Components in Chinese Medicines—Probing Herba Artemisiae Scopariae as an Exemplifying Approach

    Directory of Open Access Journals (Sweden)

    Hong-Wei Fan

    2012-02-01

    Full Text Available In order to establish an effective and quick method for screening potential bioactive compounds in Traditional Chinese Medicines (TCMs, hepatocytes were employed for extracting either bifendate, a clinical medicine for liver diseases, or chemicals in Herba Artemisiae Scopariae (A. Scopariae, a commonly used traditional Chinese medicine for remedying liver diseases such as hepatitis induced by viruses, chemicals or alcohol. After hepatocyte extraction the compounds were analyzed by HPLC, therefore this method was referrred to as hepatocyte extraction conjugated with HPLC (HE-HPLC. In the first part of this study, HE-HPLC showed that bifendate was extracted by hepatocytes and detected by HPLC-DAD which indicated the feasibility of this method. Then in the second part of the study, the potential active components in the A. scopariae extract were studied using HE-HPLC. Six chemicals in the A. scopariae extract, which could bind to hepatocytes in vitro, were detected by HPLC-DAD and three were identified as 7-hydroxy-coumarin (7-OH-C, capillartemisin A and 7-methoxy-coumarin, respectively. In vitro assays showed that 7-OH-C protected HL-7702 hepatocytes from H2O2 injury. The results indicated that these compounds could be extracted by hepatocytes, could be detected by HPLC and more importantly were bioactive. It is suggested that HE-HPLC is a useful method for screening potent active components in Chinese medicines used to treat liver diseases.

  12. Nuc-ErbB3 regulates H3K27me3 levels and HMT activity to establish epigenetic repression during peripheral myelination.

    Science.gov (United States)

    Ness, Jennifer K; Skiles, Amanda A; Yap, Eng-Hui; Fajardo, Eduardo J; Fiser, Andras; Tapinos, Nikos

    2016-06-01

    Nuc-ErbB3 an alternative transcript from the ErbB3 locus binds to a specific DNA motif and associates with Schwann cell chromatin. Here we generated a nuc-ErbB3 knockin mouse that lacks nuc-ErbB3 expression in the nucleus without affecting the neuregulin-ErbB3 receptor signaling. Nuc-ErbB3 knockin mice exhibit hypermyelination and aberrant myelination at the paranodal region. This phenotype is attributed to de-repression of myelination associated gene transcription following loss of nuc-ErbB3 and histone H3K27me3 promoter occupancy. Nuc-ErbB3 knockin mice exhibit reduced association of H3K27me3 with myelination-associated gene promoters and increased RNA Pol-II rate of transcription of these genes. In addition, nuc-ErbB3 directly regulates levels of H3K27me3 in Schwann cells. Nuc-ErbB3 knockin mice exhibit significant decrease of histone H3K27me3 methyltransferase (HMT) activity and reduced levels of H3K27me3. Collectively, nuc-ErbB3 is a master transcriptional repressor, which regulates HMT activity to establish a repressive chromatin landscape on promoters of genes during peripheral myelination.

  13. Establishment of hairy root cultures by Agrobacterium rhizogenes mediated transformation of Isatis tinctoria L. For the efficient production of flavonoids and evaluation of antioxidant activities.

    Directory of Open Access Journals (Sweden)

    Qing-Yan Gai

    Full Text Available In this work, Isatis tinctoria hairy root cultures (ITHRCs were established as an alternative source for flavonoids (FL production. I. tinctoria hairy root line V was found to be the most efficient line and was further confirmed by the PCR amplification of rolB, rolC and aux1 genes. Culture parameters of ITHRCs were optimized by Box-Behnken design (BBD, and eight bioactive FL constituents (rutin, neohesperidin, buddleoside, liquiritigenin, quercetin, isorhamnetin, kaempferol and isoliquiritigenin were quali-quantitatively determined by LC-MS/MS. Under optimal conditions, the total FL accumulation of ITHRCs (24 day-old achieved was 438.10 μg/g dry weight (DW, which exhibited significant superiority as against that of 2 year-old field grown roots (341.73 μg/g DW. Additionally, in vitro antioxidant assays demonstrated that ITHRCs extracts exhibited better antioxidant activities with lower IC₅₀ values (0.41 and 0.39, mg/mL as compared to those of field grown roots (0.56 and 0.48, mg/mL. To the best of our knowledge, this is the first report describing FL production and antioxidant activities from ITHRCs.

  14. Establishment of hairy root cultures by Agrobacterium rhizogenes mediated transformation of Isatis tinctoria L. For the efficient production of flavonoids and evaluation of antioxidant activities.

    Science.gov (United States)

    Gai, Qing-Yan; Jiao, Jiao; Luo, Meng; Wei, Zuo-Fu; Zu, Yuan-Gang; Ma, Wei; Fu, Yu-Jie

    2015-01-01

    In this work, Isatis tinctoria hairy root cultures (ITHRCs) were established as an alternative source for flavonoids (FL) production. I. tinctoria hairy root line V was found to be the most efficient line and was further confirmed by the PCR amplification of rolB, rolC and aux1 genes. Culture parameters of ITHRCs were optimized by Box-Behnken design (BBD), and eight bioactive FL constituents (rutin, neohesperidin, buddleoside, liquiritigenin, quercetin, isorhamnetin, kaempferol and isoliquiritigenin) were quali-quantitatively determined by LC-MS/MS. Under optimal conditions, the total FL accumulation of ITHRCs (24 day-old) achieved was 438.10 μg/g dry weight (DW), which exhibited significant superiority as against that of 2 year-old field grown roots (341.73 μg/g DW). Additionally, in vitro antioxidant assays demonstrated that ITHRCs extracts exhibited better antioxidant activities with lower IC₅₀ values (0.41 and 0.39, mg/mL) as compared to those of field grown roots (0.56 and 0.48, mg/mL). To the best of our knowledge, this is the first report describing FL production and antioxidant activities from ITHRCs.

  15. piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells.

    Science.gov (United States)

    Pezic, Dubravka; Manakov, Sergei A; Sachidanandam, Ravi; Aravin, Alexei A

    2014-07-01

    Transposable elements (TEs) occupy a large fraction of metazoan genomes and pose a constant threat to genomic integrity. This threat is particularly critical in germ cells, as changes in the genome that are induced by TEs will be transmitted to the next generation. Small noncoding piwi-interacting RNAs (piRNAs) recognize and silence a diverse set of TEs in germ cells. In mice, piRNA-guided transposon repression correlates with establishment of CpG DNA methylation on their sequences, yet the mechanism and the spectrum of genomic targets of piRNA silencing are unknown. Here we show that in addition to DNA methylation, the piRNA pathway is required to maintain a high level of the repressive H3K9me3 histone modification on long interspersed nuclear elements (LINEs) in germ cells. piRNA-dependent chromatin repression targets exclusively full-length elements of actively transposing LINE families, demonstrating the remarkable ability of the piRNA pathway to recognize active elements among the large number of genomic transposon fragments.

  16. Energy technology programmes 1993-1998. Evaluation report

    Energy Technology Data Exchange (ETDEWEB)

    1999-09-01

    In the late 1980s Finland`s Ministry of Trade and Industry (KTM) initiated a series of research and development (R and D) programmes in the field of energy technology. Subsequently, in 1993, it launched a further suite of eleven Energy Technology Programmes scheduled to run over the period 1993-1998. Aimed at the development of efficient and environmentally sound energy technologies intended to be competitive in the international marketplace, the programmes sought to involve the research, industrial and public sectors in some FIM 1.2 billion of research and development activity. The technology areas spanned: Combustion and gasification techniques Bioenergy, Advanced energy systems and technologies (e.g. wind, solar energy), Fusion, Energy and environmental technology, Energy and the environment in transportation, Energy use in buildings, Energy in steel and metal production, Energy in paper and board production, District heating, Electricity distribution automation. In early 1995, the Technology Development Centre of Finland (Tekes) assumed responsibility for the funding, management and administration of the programmes. As the final year of activities began, Tekes commissioned Technopolis to assemble a team to conduct a major review of all eleven programmes over the course of 1998. The broad aim of the exercise was to review the experience of the eleven technology R and D programmes and to make suggestions for the future. In particular, the intention was to cover a number of distinct levels. Most important were the Programme and Portfolio levels. At the individual Programme level, the review was to comment on the relevance, calibre and impact of programmes, concentrating in particular on the following: Relevance - were programme and project level goals in line with Finnish interests and comparable agendas in other countries; Efficiency - how well were the programmes implemented and managed; Quality - how did the scientific and technological quality of the work

  17. Establishment and evaluation of LPS stimulation on microglia activation%LPS诱导小胶质细胞活化模型的建立及评价

    Institute of Scientific and Technical Information of China (English)

    黄欢; 武汪洋; 吴阳洋; 陈寒青; 尹艳艳

    2013-01-01

    目的 探讨不同浓度脂多糖(Lipopolysaccharides,LPS)对小胶质细胞活化作用,建立小胶质细胞活化的模型.方法 不同浓度LPS(0.01,0.1,1,10,100 mg·L-1)刺激原代纯化的小胶质细胞及BV2细胞株,采用MTT法检测细胞活力;采用细胞免疫化学法观察细胞形态变化.结果 LPS(1 mg·L-1)可以明显激活原代小胶质细胞,但不影响细胞活力,OX-42染色显示小胶质细胞胞体变大,轴突变短变多,形似"阿米巴状";LPS(10 mg·L-1)可以激活BV2细胞,且不降低细胞活力,镜下观察发现BV2细胞胞体明显增大.结论 采用LPS(1 mg·L-1)刺激原代小胶质细胞,LPS(10 mg·L-1)刺激BV2细胞株,可以建立稳定的小胶质细胞活化模型.%Objective To explore the effect of different concentrations of LPS on microglia activation, and to establish the model of microglia activation. Methods Primary cultured microglia and BV2 microglia cells were stimulated with different concentrations of LPS ( 0.01,0. 1,1,10,100 mg · L-1 ). The cytotoxicity of LPS was measured by MTT assay, morphological changes of microglia were observed by immunocytochemical method. Results LPS( 1 mg · L-1 )could significantly activated primary cultured microglia but did not affect cell viability. According to the OX-42 staining pictures, after activated by LPS, the cell bodies relatively increased with multiple slender prominences like amebocytes. LPS( 10 mg · L-1 )could activate the BV2 microglia, but did not affect cell viability. Conclusion LPS( 1 mg · L-1 )stimulation of primary cultured microglia and LPS( 10 mg · L-1 )stimulation of the BV2 microglia can create a stable model of microglia activation.

  18. Finnish energy technology programmes 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-01

    The Finnish Technology Development Centre (Tekes) is responsible for the financing of research and development in the field of energy production technology. A considerable part of the financing goes to technology programmes. Each technology programme involves major Finnish institutions - companies, research institutes, universities and other relevant interests. Many of the energy technology programmes running in 1998 were launched collectively in 1993 and will be completed at the end of 1998. They are complemented by a number of other energy-related technology programmes, each with a timetable of its own. Because energy production technology is horizontal by nature, it is closely connected with research and development in other fields, too, and is an important aspect in several other Tekes technology programmes. For this reason this brochure also presents technology programmes where energy is only one of the aspects considered but which nevertheless contribute considerably to research and development in the energy production sector

  19. PREPARATION FOR RETIREMENT PROGRAMME

    CERN Multimedia

    Human Resources Division

    2001-01-01

    27 March 2001 from 2.00 p.m. to 5.30 p.m. 28 March 2001 from 2.00 p.m. to 5.30 p.m. 29 March 2001 from 2.00 p.m. to 5.30 p.m. 30 March 2001 from 2.00 p.m. to 4.45 p.m. Auditorium (Main Building) After the success of the preparation seminars held in recent years, it has been decided that the programme should continue. The forthcoming seminar has been prepared in close collaboration with the CERN Pensioners' Association. The programme will be organised over several half-day sessions. Once again this year, a special session will be devoted to the 10th revision of the Swiss state pension scheme, the 'AVS' (Assurance-Vieillesse et Survivants), and the consequences for international civil servants. A talk will be given by Mrs Danièle Siebold, Director of the Caisse Cantonale Genevoise de Compensation, aimed mainly at those residing in or intending to move to Switzerland, or who worked in Switzerland before joining CERN. To enable Mrs Siebold to respond to your concerns as effectively as possible, please ...

  20. Reactor Physics Programme

    Energy Technology Data Exchange (ETDEWEB)

    De Raedt, C

    2000-07-01

    The Reactor Physics and Department of SCK-CEN offers expertise in various areas of reactor physics, in particular in neutronics calculations, reactor dosimetry, reactor operation, reactor safety and control and non-destructive analysis on reactor fuel. This expertise is applied within the Reactor Physics and MYRRHA Research Department's own research projects in the VENUS critical facility, in the BR1 reactor and in the MYRRHA project (this project aims at designing a prototype Accelerator Driven System). Available expertise is also used in programmes external to the Department such as the reactor pressure steel vessel programme, the BR2 reactor dosimetry, and the preparation and interpretation of irradiation experiments. Progress and achievements in 1999 in the following areas are reported on: (1) investigations on the use of military plutonium in commercial power reactors; (2) neutron and gamma calculations performed for BR-2 and for other reactors; (3) the updating of neutron and gamma cross-section libraries; (4) the implementation of reactor codes; (6) the management of the UNIX workstations; and (6) fuel cycle studies.

  1. Copernicus Earth observation programme

    Science.gov (United States)

    Žlebir, Silvo

    European Earth observation program Copernicus is an EU-wide programme that integrates satellite data, in-situ data and modeling to provide user-focused information services to support policymakers, researchers, businesses and citizens. Land monitoring service and Emergency service are fully operational already, Atmosphere monitoring service and Marine environment monitoring service are preoperational and will become fully operational in the following year, while Climate change service and Security service are in an earlier development phase. New series of a number of dedicated satellite missions will be launched in the following years, operated by the European Space Agency and EUMETSAT, starting with Sentinel 1A satellite early this year. Ground based, air-borne and sea-borne in-situ data are provided by different international networks and organizations, EU member states networks etc. European Union is devoting a particular attention to secure a sustainable long-term operational provision of the services. Copernicus is also stated as a European Union’s most important contribution to Global Earth Observation System of Systems (GEOSS). The status and the recent development of the Copernicus programme will be presented, together with its future perspective. As Copernicus services have already demonstrated their usability and effectiveness, some interesting cases of their deployment will be presented. Copernicus free and open data policy, supported by a recently adopted EU legislative act, will also be presented.

  2. Programmable pH buffers

    Energy Technology Data Exchange (ETDEWEB)

    Gough, Dara Van; Huber, Dale L.; Bunker, Bruce C.; Roberts, Mark E.

    2017-01-24

    A programmable pH buffer comprises a copolymer that changes pK.sub.a at a lower critical solution temperature (LCST) in water. The copolymer comprises a thermally programmable polymer that undergoes a hydrophobic-to-hydrophilic phase change at the LCST and an electrolytic polymer that exhibits acid-base properties that are responsive to the phase change. The programmable pH buffer can be used to sequester CO.sub.2 into water.

  3. Programmable fast data acquisition system

    Science.gov (United States)

    Montebugnoli, S.; Bianchi, G.; Zoni, L.

    The goal of this work is to investigate the possibility to install on modern radiotelescopes a fast and programmable backend instead of several backends, each dedicated to a single acquisition task. Such an approach could lower the costs and make available a more compact and flexible back end. Exploiting the state-of-the-art of the FPGAs (Field Programmable Gate Arrays) and innovative architectures, a programmable system might be conceived.

  4. Physics R and D programme

    Energy Technology Data Exchange (ETDEWEB)

    Engelmann, F.; Pacher, H.D. (Max-Planck-Institut fuer Plasmaphysik, Garching (Germany, F.R.)); Fujisawa, N.; Sugihara, M.; Tsunematsu, T. (Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan)); Luxon, J. (General Atomics, San Diego, CA (USA)); Mukhovatov, V. (Gosudarstvennyj Komitet po Ispol' zovaniyu Atomnoj Ehnergii SSSR, Moscow (USSR). Inst. Atomnoj Ehnergii); Post, D.; Young, K. (Princeton Un

    1990-12-01

    ITER-Related Physics R and D Programmes were set up in two steps: A first programme covering the latter part of the ITER conceptual design phase (1989--1990) was generated and agreed between summer 1988 and spring 1989, and partial results have been reported. A second programme is being developed, to provide the data base necessary for supporting the decision to start ITER construction and to be carried out in parallel with the ITER engineering design (1991--1995).

  5. SLC7 family transporters control the establishment of left-right asymmetry during organogenesis in medaka by activating mTOR signaling.

    Science.gov (United States)

    Asaoka, Yoichi; Nagai, Yoko; Namae, Misako; Furutani-Seiki, Makoto; Nishina, Hiroshi

    2016-05-20

    The precise government of the left-right (LR) specification of an organ is an essential aspect of its morphogenesis. Multiple signaling cascades have been implicated in the establishment of vertebrate LR asymmetry. Recently, mTOR signaling was found to critically regulate the development of LR asymmetry in zebrafish. However, the upstream factor(s) that activate mTOR signaling in the context of LR specification are as yet unknown. In this study, we identify the SLC7 amino acid transporters Slc7a7 and Slc7a8 as novel regulators of LR asymmetry development in the small fish medaka. Knockdown of Slc7a7 and/or Slc7a8 in medaka embryos disrupted LR organ asymmetries. Depletion of Slc7a7 hindered left-sided expression of the southpaw (spaw) gene, which is responsible for LR axis determination. Work at the cellular level revealed that Slc7a7 coordinates ciliogenesis in the epithelium of Kupffer's vesicle and thereby the generation of the nodal fluid flow required for LR asymmetry. Interestingly, knockdown of Slc7a7 depressed mTOR signaling activity in medaka embryos. Treatment with rapamycin, an inhibitor of mTOR signaling, together with Slc7a7 knockdown synergistically perturbed spaw expression, indicating an interaction between Slc7a7 and mTOR signaling affecting gene expression required for LR specification. Taken together, our results demonstrate that Slc7a7 governs the regulation of LR asymmetry development via the activation of mTOR signaling.

  6. Evaluation of the medical student research programme in Norwegian medical schools. A survey of students and supervisors

    Directory of Open Access Journals (Sweden)

    Tømmerås Karin

    2009-07-01

    Full Text Available Abstract Background The Medical Student Research Programme is a national education and grant scheme for medical students who wish to carry out research in parallel with their studies. The purpose of the programme is to increase recruitment of people with a standard medical degree to medical research. The Research Programme was established in 2002 and underwent a thorough evaluation during the spring of 2007. The evaluation should investigate if the programme had fulfilled its objectives of increased recruitment to medical research, in addition to the students' and supervisors' satisfaction of the programme, and unwanted differences between the universities. Methods Data was collected from students, supervisors and administrative staff via web-based questionnaires. Information about admission, implementation, results achieved and satisfaction was analysed and compared between the four Norwegian medical schools. In addition, the position of the scheme in relation to the national Quality Reform of Higher Education was analysed. Results At the end of 2006, the Medical Student Research Programme had recruited 265 medical students to research. These consisted of 214 active students, 35 who had completed their studies and only 17 who had dropped out. Both students and supervisors were generally very satisfied with the scheme, including the curriculum, the results achieved and the administrative service. The majority of students wanted to continue their research towards a PhD and, of those who had completed the Medical Student Research Programme, practically all had published one or several scientific papers. The survey showed only small differences between the four medical schools, despite their choice of somewhat different solutions in terms of administration and organisation. The Medical Student Research Programme satisfies the majority of the demands of the Quality Reform, however as an integrated research programme aimed at a PhD it presupposes

  7. What promotes sustainability in Safe Community programmes?

    Directory of Open Access Journals (Sweden)

    Lindqvist Kent

    2009-01-01

    . Increased relational resources facilitated the transfer of information. A regular flow of information to policy-makers, residents, and staff was needed in order to integrate safety programmes into routines. Adopting a bottom-up approach requires that informal and ad hoc activities in information management be replaced by formalized, organizationally sanctioned routines. In contrast to injury prevention, which focuses on technical solutions, safety promotion tries to influence attitudes. Collaboration with the media was an area that could be improved.

  8. A Study on the Translation of Erasmus+Programme Guide

    Institute of Scientific and Technical Information of China (English)

    韩姣

    2016-01-01

    In 2014, the European Commission carries out a new programme----"Erasmus+ Programme". It increases people's skills and employability through provides grants to support students, trainees, staff and volunteers to study or work abroad and organizations to organize activities. In order to let more Chinese people know about"Erasmus+Programme"and participate in it, the author of the paper just selects its introductory part Erasmus+Programme Guide to translate. While translating, the author of the paper finds that certain translation theory and correspondent translation methods must be adopted to guide the translation in order to produce a correct and expressive version. The paper is hence intended to study the translation theory and translation methods adopted in the translation of Erasmus+Programme Guide.

  9. Konaklama İşletmelerinde İşe Alıştırma Eğitiminin Örgütsel Bağlılığa Etkisi(The Effect of Orientation Programme on Organisational Commitment in Hospitality Establishments)

    OpenAIRE

    Edip ÖRÜCÜ; Hakan BOZ

    2014-01-01

    Organisational commitment is one of the most important variable to determine of emplyee’s behavior. Morover organisational commitment is a major predictor of employees behaviors such as e,g. turnover intention, job loyalty, job performance and motivation. On the other hand orientation rogramme is a crucial process to develop an uniform organisational culture. Orientation programme has inversely relationship with turnover behaviour. For this reason the purpose of this study is to examine rela...

  10. Validation of dose calculation programmes for recycling

    Energy Technology Data Exchange (ETDEWEB)

    Menon, Shankar [Menon Consulting, Nykoeping (Sweden); Brun-Yaba, Christine [Inst. de Radioprotection et Securite Nucleaire (France); Yu, Charley; Cheng, Jing-Jy [Argonne National Laboratory, IL (United States). Environmental Assessment Div.; Bjerler, Jan [Studsvik Stensand, Nykoeping (Sweden); Williams, Alexander [Dept. of Energy (United States). Office of Environmental Management

    2002-12-01

    This report contains the results from an international project initiated by the SSI in 1999. The primary purpose of the project was to validate some of the computer codes that are used to estimate radiation doses due to the recycling of scrap metal. The secondary purpose of the validation project was to give a quantification of the level of conservatism in clearance levels based on these codes. Specifically, the computer codes RESRAD-RECYCLE and CERISE were used to calculate radiation doses to individuals during the processing of slightly contaminated material, mainly in Studsvik, Sweden. Calculated external doses were compared with measured data from different steps of the process. The comparison of calculations and measurements shows that the computer code calculations resulted in both overestimations and underestimations of the external doses for different recycling activities. The SSI draws the conclusion that the accuracy is within one order of magnitude when experienced modellers use their programmes to calculate external radiation doses for a recycling process involving material that is mainly contaminated with cobalt-60. No errors in the codes themselves were found. Instead, the inaccuracy seems to depend mainly on the choice of some modelling parameters related to the receptor (e.g., distance, time, etc.) and simplifications made to facilitate modelling with the codes (e.g., object geometry). Clearance levels are often based on studies on enveloping scenarios that are designed to cover all realistic exposure pathways. It is obvious that for most practical cases, this gives a margin to the individual dose constraint (in the order of 10 micro sievert per year within the EC). This may be accentuated by the use of conservative assumptions when modelling the enveloping scenarios. Since there can obviously be a fairly large inaccuracy in the calculations, it seems reasonable to consider some degree of conservatism when establishing clearance levels based on

  11. African Primary Care Research: Performing a programme evaluation

    Directory of Open Access Journals (Sweden)

    Lilian Dudley

    2014-06-01

    Full Text Available This article is part of a series on Primary Care Research in the African context and focuses on programme evaluation. Different types of programme evaluation are outlined: developmental, process, outcome and impact. Eight steps to follow in designing your programme evaluation are then described in some detail: engage stakeholders; establish what is known; describe the programme; define the evaluation and select a study design; define the indicators; plan and manage data collection and analysis; make judgements and recommendations; and disseminate the findings. Other articles in the series cover related topics such as writing your research proposal, performing a literature review, conducting surveys with questionnaires, qualitative interviewing and approaches to quantitative and qualitative data analysis.

  12. Programmable Cadence Timer

    Science.gov (United States)

    Hall, William A.; Gilbert, John

    1990-01-01

    Electronic metronome paces users through wide range of exercise routines. Conceptual programmable cadence timer provides rhythmic aural and visual cues. Timer automatically changes cadence according to program entered by the user. It also functions as clock, stopwatch, or alarm. Modular pacer operated as single unit or as two units. With audiovisual module moved away from base module, user concentrates on exercise cues without distraction from information appearing on the liquid-crystal display. Variety of uses in rehabilitative medicine, experimental medicine, sports, and gymnastics. Used in intermittent positive-pressure breathing treatment, in which patient must rhythmically inhale and retain medication delivered under positive pressure; and in incentive spirometer treatment, in which patient must inhale maximally at regular intervals.

  13. Programmable ferroelectric tunnel memristor

    Directory of Open Access Journals (Sweden)

    Andy eQuindeau

    2014-02-01

    Full Text Available We report an analogously programmable memristor based on genuine electronic resistive switching combining ferroelectric switching and electron tunneling. The tunnel current through an 8 unit cell thick epitaxial Pb(Zr[0.2]Ti[0.8]O[3] film sandwiched between La[0.7]Sr[0.3]MnO[3] and cobalt electrodes obeys the Kolmogorov-Avrami-Ishibashi model for bidimensional growth with a characteristic switching time in the order of 10^-7 seconds. The analytical description of switching kinetics allows us to develop a characteristic transfer function that has only one parameter viz. the characteristic switching time and fully predicts the resistive states of this type of memristor.

  14. DESIGNING OF COMPUTER AIDED AND USER INTERACTIVE CNC PART PROGRAMME FOR A MILLING MACHINE

    Directory of Open Access Journals (Sweden)

    M. Ali DÖNERTAŞ

    2005-02-01

    Full Text Available In this study, a user–interactive computer programme generating CNC part programme according to dialog method has been developed. The design of programme has been prepared like a CAM programme structure. The part programme was established by required parameters asking to the user with a specific order. Subsequently, this parameters are used to create M and G codes, and these codes are showed at a different page on the screen. In addition, these code pages can be stored with "txt" format. This program includes basic processes and the programme design has been prepared for milling machine working according to Fanuc system. The computer programme was written by using Delphi 6 programming language.

  15. An activity stimulation programme during a child's first year reduces some indicators of adiposity at the age of two-and-a-half

    NARCIS (Netherlands)

    de Vries, Agm; Huiting, H. G.; van den Heuvel, Er; L'Abée, C; Corpeleijn, E; Stolk, Rp

    2015-01-01

    AIM: Obesity tracks from childhood into adulthood. We evaluated the effect of early stimulation of physical activity on growth, body composition, motor activity and motor development in toddlers. METHODS: We performed a cluster randomised controlled single-blinded trial in Dutch Well Baby Clinics, w

  16. The effect a of community-based social marketing campaign on recruitment and retention of low-income groups into physical activity programmes - a controlled before-and-after study

    Directory of Open Access Journals (Sweden)

    Withall Janet

    2012-10-01

    Full Text Available Abstract Background The beneficial effect of physical activity for the prevention of a range of chronic diseases is widely acknowledged. These conditions are most prevalent in low-income groups where physical activity levels are consistently lower. Social marketing is the government’s recommended approach to promoting physical activity but evidence of its effectiveness is limited. The purpose of this study was to examine the effect of a social marketing campaign on the monthly recruitment, attendance and retention levels at a community-based physical activity programme in a low income area. Methods A six-month social marketing campaign was designed and delivered in a highly-deprived suburban neighbourhood. Analysis of variance was used to assess effects on recruitment and attendance. χ2 tests of independence were used to compare dropouts and adherers and effectiveness of recruitment mechanisms. Percentages were used to compare adherence rates at intervention, pre-existing sessions in the intervention area and control area sessions. Results Attendance data were collected weekly and presented and analysed monthly to provide a view of changing participation over the six month intervention period, as compared to attendance at pre-existing sessions in the intervention area and in a control area. Recruitment into intervention sessions was significantly greater than into pre-existing and control area sessions in Month 1 (18.13v1.04 p = .007, 18.13v.30 p=.005, Month 5 (3.45v.84 p=.007, 3.45v.30 p Conclusions Direct comparisons with other programmes were difficult due to a lack of standard definitions of recruitment and adherence and limited reporting of findings. However when compared to pre-existing sessions and sessions delivered in a control area, monthly attendance patterns indicated that a reasonably well funded social marketing campaign increased recruitment into exercise sessions, maintained good levels of attendance and reasonable levels

  17. The effect a of community-based social marketing campaign on recruitment and retention of low-income groups into physical activity programmes - a controlled before-and-after study

    Science.gov (United States)

    2012-01-01

    Background The beneficial effect of physical activity for the prevention of a range of chronic diseases is widely acknowledged. These conditions are most prevalent in low-income groups where physical activity levels are consistently lower. Social marketing is the government’s recommended approach to promoting physical activity but evidence of its effectiveness is limited. The purpose of this study was to examine the effect of a social marketing campaign on the monthly recruitment, attendance and retention levels at a community-based physical activity programme in a low income area. Methods A six-month social marketing campaign was designed and delivered in a highly-deprived suburban neighbourhood. Analysis of variance was used to assess effects on recruitment and attendance. χ2 tests of independence were used to compare dropouts and adherers and effectiveness of recruitment mechanisms. Percentages were used to compare adherence rates at intervention, pre-existing sessions in the intervention area and control area sessions. Results Attendance data were collected weekly and presented and analysed monthly to provide a view of changing participation over the six month intervention period, as compared to attendance at pre-existing sessions in the intervention area and in a control area. Recruitment into intervention sessions was significantly greater than into pre-existing and control area sessions in Month 1 (18.13v1.04 p = .007, 18.13v.30 p=.005), Month 5 (3.45v.84 p=.007, 3.45v.30 pmarketing techniques (posters/outdoor banners/flyers) had the greatest influence on recruitment compared to word of mouth communication (84.5%v15.5%). In months five and six word of mouth influenced 57.5% of new recruits. Conclusions Direct comparisons with other programmes were difficult due to a lack of standard definitions of recruitment and adherence and limited reporting of findings. However when compared to pre-existing sessions and sessions delivered in a control area

  18. The effect a of community-based social marketing campaign on recruitment and retention of low-income groups into physical activity programmes - a controlled before-and-after study.

    Science.gov (United States)

    Withall, Janet; Jago, Russell; Fox, Kenneth R

    2012-10-02

    The beneficial effect of physical activity for the prevention of a range of chronic diseases is widely acknowledged. These conditions are most prevalent in low-income groups where physical activity levels are consistently lower. Social marketing is the government's recommended approach to promoting physical activity but evidence of its effectiveness is limited. The purpose of this study was to examine the effect of a social marketing campaign on the monthly recruitment, attendance and retention levels at a community-based physical activity programme in a low income area. A six-month social marketing campaign was designed and delivered in a highly-deprived suburban neighbourhood. Analysis of variance was used to assess effects on recruitment and attendance. χ2 tests of independence were used to compare dropouts and adherers and effectiveness of recruitment mechanisms. Percentages were used to compare adherence rates at intervention, pre-existing sessions in the intervention area and control area sessions. Attendance data were collected weekly and presented and analysed monthly to provide a view of changing participation over the six month intervention period, as compared to attendance at pre-existing sessions in the intervention area and in a control area. Recruitment into intervention sessions was significantly greater than into pre-existing and control area sessions in Month 1 (18.13v1.04 p = .007, 18.13v.30 p=.005), Month 5 (3.45v.84 p=.007, 3.45v.30 pmarketing techniques (posters/outdoor banners/flyers) had the greatest influence on recruitment compared to word of mouth communication (84.5%v15.5%). In months five and six word of mouth influenced 57.5% of new recruits. Direct comparisons with other programmes were difficult due to a lack of standard definitions of recruitment and adherence and limited reporting of findings. However when compared to pre-existing sessions and sessions delivered in a control area, monthly attendance patterns indicated that a

  19. International Geological Correlation Programme (IGCP) /International Geoscience Programme (IGCP)

    Institute of Scientific and Technical Information of China (English)

    WolfgangEder; MargaretePatzak

    2004-01-01

    Although many countries, especially from the developing world, share the most exciting geological features, geological structures and natural resources, research activities at various institutions are undertaken in isolation. The IGCP is unique as an international Programme that brings together several thousands of scientists from different disciplines, to stimulate dialogue and facilitate communication among

  20. Programmable architecture for quantum computing

    NARCIS (Netherlands)

    Chen, J.; Wang, L.; Charbon, E.; Wang, B.

    2013-01-01

    A programmable architecture called “quantum FPGA (field-programmable gate array)” (QFPGA) is presented for quantum computing, which is a hybrid model combining the advantages of the qubus system and the measurement-based quantum computation. There are two kinds of buses in QFPGA, the local bus and t

  1. Ny software helt uden programmering

    DEFF Research Database (Denmark)

    Kindler, Ekkart

    2010-01-01

    Fremtiden er modelbaseret softwareudvikling. Men er det bare en våd drøm, eller er det realistisk at tro, at man kan lave software uden programmering?......Fremtiden er modelbaseret softwareudvikling. Men er det bare en våd drøm, eller er det realistisk at tro, at man kan lave software uden programmering?...

  2. Programmable architecture for quantum computing

    NARCIS (Netherlands)

    Chen, J.; Wang, L.; Charbon, E.; Wang, B.

    2013-01-01

    A programmable architecture called “quantum FPGA (field-programmable gate array)” (QFPGA) is presented for quantum computing, which is a hybrid model combining the advantages of the qubus system and the measurement-based quantum computation. There are two kinds of buses in QFPGA, the local bus and t

  3. An automatic bibliography indexing programme

    Directory of Open Access Journals (Sweden)

    J. W. Morris

    1974-12-01

    Full Text Available A relatively simple FORTRAN IV programme, designed for a small computer, for author and key-word indexes to bibliographic records is described, and examples of output are given. It is com­pared with some other systems. Suggested improvements to the programme are given.

  4. Japan's Eco-School Programme

    Science.gov (United States)

    Mori, Masayuki

    2007-01-01

    Since 1997, several ministries in Japan have collaborated on an eco-school programme, which applies to both newly constructed and renovated school buildings, in an effort to make its schools more environmentally friendly. The programme equips school buildings with ecological features such as photovoltaic cells, solar thermal collectors, other new…

  5. The Objectives of the Egyptian Space Programme

    Science.gov (United States)

    Shaltout, Mosalam

    : The aim of the Egyptsat series is to build on the experience gained from these missions to extend Egypt's space effort into scientific research and to expand its role in educational, agricultural and other development fields. The Egyptian Space Programme envisages that Egypt will be able to join the space age through the gradual establishment of the facilities needed for the manufacture of small research and remote sensing satellites, by acquiring appropriate technological knowledge and capabilities, and by building up the necessary infrastructure to enable the country to design and manufacture its own small satellites. Included in this overall vision would be the capacity to utilize space technologies And applications to serve the national development plans and contribute to the development of scientific and technological research in Egypt, as well as to the establishment of a scientific and research base for advanced industries in Egypt. To hasten the achievement of some or all of these objectives, it will be necessary to: • Transfer advanced space technologies in communication, computers, programs, optics, sensors, new materials, command and control, and energy into the domain of the Egyptian scientific community. • Utilize space technologies and apply these to the country's development plans. • Acquire national capabilities in space technology disciplines. Establish scientific and industrial base in advanced technology fields. • Enhance our human resource capabilities for space sciences fields. • Promote cooperation between the country's research and industrial centres in order to bring about successful project within the national space programme.

  6. Wheels, hubs and spokes: incorporating a scorecard into a business continuity programme.

    Science.gov (United States)

    Stourac, Tracy

    2014-01-01

    A scorecard can provide much more than periodic measurements; it can actually serve as the 'hub' of a programme. By taking a strategic look at what one is trying to accomplish, using consistent messaging, following a flexible but defined process and creating an actionable report for the senior leadership, a programme can be built that not only gets attention but is also efficient and effective. The scorecard establishes accountability and consistency while creating a brand for a business continuity programme.

  7. Understanding elite commitment to social protection: Rwanda's Vision 2020 Umurenge Programme

    OpenAIRE

    Lavers, Tom

    2016-01-01

    This paper examines the political economy of Rwanda's Vision 2020 Umurenge Programme, concluding that strong government commitment to the programme has been shaped by the specific characteristics of the political settlement that was established around 2000. For the Rwandan government, the programme has never been just about social transfer, but a key part of the development strategy that aims to promote social stability and the legitimacy of the ruling coalition through rapid socioeconomic de...

  8. The Wind Energy programme - SFOE Research Programme 2000 - 2003; Programm Wind. Konzept BFE-Forschungsprogramm 'Wind' 2000 - 2003

    Energy Technology Data Exchange (ETDEWEB)

    Horbaty, R.

    2001-07-01

    This document, issued by the Swiss Federal Office of Energy (SFOE) describes the concept behind the Swiss wind energy programme. The first part of the report discusses the origins and development of the wind energy programme in Switzerland, discussing the importance of wind energy and policy matters associated with its promotion. The experience gained during the previous research programmes is reviewed. The degree to which targets were reached, promotional activities, the central government's own wind energy activities and the results of a programme evaluation are discussed. Lists of projects that have been realised and activities that have been carried out are presented and positive and negative influences on development are noted. A second part is dedicated to the goals of the wind energy programme in terms of target figures for the year 2010 and the strategies chosen to reach these goals, including pilot and demonstration projects (P and D) and promotional activities. Details of the P and D programme including lists of wind-power projects to be supported, the priorities that have been set and information and further education that is to be provided, are given. New activities in the wind power area such as the development of new type of wind turbine especially suited to alpine conditions are discussed. The role of the Swiss Association for Wind Energy 'Suisse Eole' as a network-partner in the wind energy programme is discussed. An appendix provides details of wind energy projects in Switzerland, market partners and customers. The results of a survey made of wind energy activities at Swiss institutes of higher education are presented.

  9. Situational analysis of infant and young child nutrition policies and programmatic activities in Senegal.

    Science.gov (United States)

    Wuehler, Sara E; Ly Wane, Coudy Thierno

    2011-04-01

    Progress towards reducing mortality and malnutrition among children nutrition in the Sahel', starting with an analysis of current activities related to infant and young child nutrition (IYCN). The main objectives of the situational analysis are to compile, analyse and interpret available information on infant and child feeding and the nutrition situation of children nutrition division was developed to support a national nutrition strengthening programme; (4) the national nutrition counsel was organized to coordinate nutritional activities across various organizations and governmental sectors, involving representatives from health, agriculture and surveillance; and (5) an integrated communications programme was developed to support harmonized behaviour change communication tools for the health and nutrition sectors. Along with these activities, a number of programme evaluations were conducted to ensure that programmes obtain desired results. Although useful, these evaluations were not rigorous enough to identify effective programmes that contributed to the mentioned reductions in the prevalence of underweight and mortality, and increases in exclusive breastfeeding. The policy and programme framework is well established for support of optimal IYCN practices in Senegal. Despite the recent improvements in infant and young child nutritional status indicators, there is still much to do. Greater resources and continued capacity building are needed to: (1) conduct necessary research for adapting training materials and programme protocols to programmatic needs; (2) improve and carry out monitoring and evaluation that identify effective programme components; and (3) apply these findings in developing, expanding and improving effective programmes.

  10. The Brazilian programme for labelling photovoltaic systems

    Energy Technology Data Exchange (ETDEWEB)

    Galdino, Marco Antonio; Lima, Jorge Henrique [Centro de Pesquisas de Energia Eletrica (CEPEL), Rio de Janeiro, RJ (Brazil)], E-mail: marcoag@cepel.br; Novgorodcev, Alexandre [Instituto Nacional de Metrologia, Normalizacao e Qualidade Industrial (PBE/INMETRO), Brasilia, DF (Brazil). Programa Brasileiro de Etiquetagem; Zilles, Roberto [Universidade de Sao Paulo (IEE/USP), SP (Brazil). Inst. de Eletrotecnica e Energia; Zanesco, Izete; Moehlecke, Adriano [Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Porto Alegre, RS (Brazil); Krenzinger, Arno [Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS (Brazil); Orlando, Alcir de Faro [Pontificia Universidade Catolica do Rio de Janeiro (PUC-Rio), Rio de Janeiro, RJ (Brazil)

    2003-07-01

    A great increase in the installation of stand-alone PV systems for rural electrification is expected in Brazil for the next years due to a government program named Luz para Todos. However, there is a major concern for the quality of the equipment and systems to be acquired and installed, which led to an initiative, coordinated by INMETRO - Brazilian Institute for Metrology, Standardisation and Industrial Quality (Instituto Brasileiro de Metrologia, Normalizacao e Qualidade Industrial), joining several institutions to establish a programme for labelling these equipment. The adopted requirements are discussed in the present article. (author)

  11. THORPEX: A Global Atmospheric Research Programme

    Science.gov (United States)

    Thorpe, A.; Shapiro, M.

    2003-04-01

    THORPEX: A Global Atmospheric Research Programme is a ten-year international programme designed to accelerate improvements in short-range (up to 3 days), medium-range (3 to 7 days) and extended-range (week two) weather predictions, and to establish the societal &economic value of advanced forecast products. The programme builds upon ongoing advances within the basic-research and operational-forecasting and communities. These include: advances in the science of atmospheric predictability; new observing and data assimilation techniques; relentless advances in computational technology; improved models; increasing needs of society for weather forecast information. The integration of these advances, together with the concept of using the weather prediction system to determine when, where and what observations will lead to the greatest improvement in forecasts, offers a new paradigm in weather prediction; namely a dynamically controlled, two-way interactive, process encompassing the forecast system and societal needs. This is the THORPEX Paradigm. It applies to weather predictions out to two weeks and beyond, for which the prediction of local high-impact weather is strongly dependent on global-to-regional atmospheric and oceanic structure and the associated dynamical processes. THORPEX plans and ongoing research will be presented.

  12. The Technical Student Programme draws Norwegians

    CERN Multimedia

    2005-01-01

    Erik Hejne, second from left, Chairman of the Technical Students Committee, and Jens Vigen, who is concerned spefically with Norwegian students at CERN, with some of the Norwegian technical students who arrived at CERN in spring 2005, together with their teachers. From mid-April, CERN's PH and IT Departments are hosting ten Norwegian students from Bergen University College, the Sør-Trøndelag University College and the University of Science and Technology in Trondheim to take part in the Laboratory's Technical Student Programme. The Technical Student Programme is open to students of universities and technical higher education establishments in the Member States who, in the course of their studies, are required to complete a period of professional training in industry or in a laboratory. Around 70 Technical Students come to work at CERN each year. Selected by a committee, they spend between six months and one year with the Organization. The programme is funded by CERN. However, once the Laboratory's quota of...

  13. The ESA Space Situational Awareness Preparatory Programme

    Science.gov (United States)

    Bobrinsky, Nicolas

    A new ESA Programme on Space Situational Awareness (SSA) has been approved during the ESA Council at Ministerial level in November 2008. A preparatory phase is in progress, covering the timeframe 2009 -2012. It concentrates on the architectural design of the SSA System, its governance and data policy, as well as on the provision of precursor services based on the federation of existing National and European assets. A continuation of the SSA programme will be proposed at the next Ministerial Council for the years 2012 and onwards. The SSA Preparatory Programme covers three distinct segments, namely: -Space Surveillance and Tracking of artificial objects orbiting the Earth -Space Weather -Near Earth Objects Each of the above segments has a strong relation with Science and is supported by specific RD Programmes at National, EC and ESA levels. In this paper, the scientific aspects of the three SSA Segments are outlined and the following main topics developed: • Space Surveillance: statistical models of the evolution of the space debris population in Earth-bound orbits, study of active mitigation measures, impact analysis, tracking and char-acterisation principles based on radar and optical techniques. • Space Weather: awareness of the natural space environment, detection and forecasting of space weather effects and interferences, analysis of appropriate ground and space-based sensors for the monitoring of the Sun, the solar wind, the radiation belts, the magnetosphere and the ionosphere. • Near Earth Objects (NEOs): methods for determination of physical characteristics of newly discovered objects, study of appropriate sensors based on radar and optical techniques, iden-tification and ranking of collision risks of NEOs with the Earth, study of possible mitigation measures (e.g. Don Quichotes project). The research topics undertaken during the preparatory programme, as well as those foreseen during the next phase, possibly with a strong international cooperation

  14. South African southern ocean research programme

    CSIR Research Space (South Africa)

    SASCAR

    1987-01-01

    Full Text Available This document describes the South African National Antarctic Research Programme's (SANARP) physical, chemical and biological Southern Ocean research programme. The programme has three main components: ecological studies of the Prince Edward Islands...

  15. STRENGTHEN AND UPGRADE REGIONAL CAPABILITIES (REGIONAL UNIVERSITY KNOWLEDGE CENTRE PROGRAMME IN HUNGARY

    Directory of Open Access Journals (Sweden)

    Annamária INZELT

    2008-06-01

    Full Text Available The emerging vision of the modern, innovative Hungarian economy, which can compete successfully in the global arena, made it absolutely necessary to encourage business firms to be innovation-oriented and to encourage universities to develop, beyond their traditional teaching mission, also their research performance and their capabilities to transfer research results and new knowledge to convert them into commercially relevant innovations. The role of government was to create a suitable legal environment and proper incentives to stimulate and support change and to enable collaborations between Public and Private Sector actors. Despite all efforts in launching relevant programmes, the competency and attractiveness of universities for strategic research partnerships with the private sector remained heterogeneous and partially unsatisfactory because of shortcomings in their knowledge base and their capability to act as well-performing research partners in collaborative projects. In 2004 Hungary established a new complementary programme which addressed particularly these shortcomings, the Pázmány Péter – Regional University Knowledge Centre programme. This paper describes shortly the programme and then investigates the experiences of two initial calls. This Public-Private-Partnership model, where the state is not the single supporter of the programme, the participating Private Sector actors provide complementary funding. In addition, the centres can also attract external funding from various other sources. In addition, Private Sector enterprises make advanced technical equipment available for use by members and non-members. By the first experiences this programme is a good frame to support overcoming on one of the failure of the system, weak knowledge distribution capability. This initiative, the Pázmány Péter programme provides a potentially transferable example for other countries with shortcomings similar to those of Hungary’s National

  16. RegA Plays a Key Role in Oxygen-Dependent Establishment of Persistence and in Isocitrate Lyase Activity, a Critical Determinant of In vivo Brucella suis Pathogenicity

    Directory of Open Access Journals (Sweden)

    Elias Abdou

    2017-05-01

    Full Text Available For aerobic human pathogens, adaptation to hypoxia is a critical factor for the establishment of persistent infections, as oxygen availability is low inside the host. The two-component system RegB/A of Brucella suis plays a central role in the control of respiratory systems adapted to oxygen deficiency, and in persistence in vivo. Using an original “in vitro model of persistence” consisting in gradual oxygen depletion, we compared transcriptomes and proteomes of wild-type and ΔregA strains to identify the RegA-regulon potentially involved in the set-up of persistence. Consecutive to oxygen consumption resulting in growth arrest, 12% of the genes in B. suis were potentially controlled directly or indirectly by RegA, among which numerous transcriptional regulators were up-regulated. In contrast, genes or proteins involved in envelope biogenesis and in cellular division were repressed, suggesting a possible role for RegA in the set-up of a non-proliferative persistence state. Importantly, the greatest number of the RegA-repressed genes and proteins, including aceA encoding the functional IsoCitrate Lyase (ICL, were involved in energy production. A potential consequence of this RegA impact may be the slowing-down of the central metabolism as B. suis progressively enters into persistence. Moreover, ICL is an essential determinant of pathogenesis and long-term interactions with the host, as demonstrated by the strict dependence of B. suis on ICL activity for multiplication and persistence during in vivo infection. RegA regulates gene or protein expression of all functional groups, which is why RegA is a key regulator of B. suis in adaptation to oxygen depletion. This function may contribute to the constraint of bacterial growth, typical of chronic infection. Oxygen-dependent activation of two-component systems that control persistence regulons, shared by several aerobic human pathogens, has not been studied in Brucella sp. before. This work

  17. FPGAs for software programmers

    CERN Document Server

    Hannig, Frank; Ziener, Daniel

    2016-01-01

    This book makes powerful Field Programmable Gate Array (FPGA) and reconfigurable technology accessible to software engineers by covering different state-of-the-art high-level synthesis approaches (e.g., OpenCL and several C-to-gates compilers). It introduces FPGA technology, its programming model, and how various applications can be implemented on FPGAs without going through low-level hardware design phases. Readers will get a realistic sense for problems that are suited for FPGAs and how to implement them from a software designer’s point of view. The authors demonstrate that FPGAs and their programming model reflect the needs of stream processing problems much better than traditional CPU or GPU architectures, making them well-suited for a wide variety of systems, from embedded systems performing sensor processing to large setups for Big Data number crunching. This book serves as an invaluable tool for software designers and FPGA design engineers who are interested in high design productivity through behavi...

  18. Management and Communication programme

    CERN Multimedia

    Nathalie Dumeaux

    2005-01-01

    We are pleased to announce the launch of three new courses in the Management and Communication programme: 1.     Managing Time (Open to all Staff Members) The objectives are: To enhance your personal effectiveness through better organisation skills To acquire ways of making the most of your time through improved work habits To reduce stress For the description of this course, please see:  http://humanresources.web.cern.ch/humanresources/external/training/MANCO/P9798/S8E_e.asp 2.     Service Orientation (Open to all Staff Members working in a service-related function) The objectives are: To understand the key elements in an effective client/service provider relationship To develop a client focused approach to providing services For the description of this course, please see:  http://humanresources.web.cern.ch/humanresources/external/training/MANCO/P9798/serv_e.asp 3.   Introduction to Leadership (Open to Staff in Career Paths E & above, including newly appointed supervisors and Sect...

  19. Management and Communication programme

    CERN Multimedia

    Nathalie Dumeaux

    2005-01-01

    We are pleased to announce the launch of three new courses in the Management and Communication programme: 1.     Managing Time (Open to all Staff Members) The objectives are: To enhance your personal effectiveness through better organisation skills To acquire ways of making the most of your time through improved work habits To reduce stress For the description of this course, please see:  http://humanresources.web.cern.ch/humanresources/external/training/MANCO/P9798/S8E_e.asp 2.     Service Orientation (Open to all Staff Members working in a service-related function) The objectives are: To understand the key elements in an effective client/service provider relationship To develop a client focused approach to providing services For the description of this course, please see:  http://humanresources.web.cern.ch/humanresources/external/training/MANCO/P9798/serv_e.asp 3.   Introduction to Leadership (Open to Staff in Career Paths E & above, including newly appointed supervisors and Secti...

  20. Summer Student Lecture Programme

    CERN Multimedia

    2004-01-01

    Main Auditorium, bldg. 500 More Information DATE TIME LECTURER TITLE Wednesday 7 July 09:15 - 10:00 L. Fayard, O. Ullaland, D. Heagerty (CERN) Programme Presentation Workshops presentation Information on Computing Rules 10:15 - 11:00 R. Aymar (CERN) Introduction to CERN (1/2) 11:15 - 12:00 J. Engelen (CERN) Introduction to CERN (2/2) 15:00 - 16:30 H. Menzel (CERN) An Introduction to Radiation Protection DATE TIME LECTURER TITLE Thursday 8 july 09:15 - 10:00 L. Di Lella (CERN) Introduction to Particle Physics (1/4) 10:15 - 11:00 L. Di Lella (CERN) Introduction to Particle Physics (2/4) 11:15 - 12:00 P. Chomaz (GANIL / CERN) Fundamental questions in modern nuclear physics: The challenge of exotic nuclei (1/2) DATE TIME LECTURER TITLE Friday 9 July 09:15 - 10:00 L. Di Lella (CERN) Introduction to Particle Physics (3/4) 10:15 - 11:00 P. Chomaz (GANIL / CERN) Fundamental questions in modern nuclear physics: The challenge of exotic nuclei (2/2) 11:15 - 12:00 P....

  1. Summer Student Programme

    CERN Multimedia

    2006-01-01

    Date Time Title Speaker 05/07/2006 09:15 - 10:00 Presentation of the Summer Student Programme F. CERUTTI Information on Computing Rules D. HEAGERTY Workshops presentation O. ULLALAND 10:15 - 11:00 Introduction to CERN J. ENGELEN 11:15 Film on CERN 11:00 Introduction to Particle Physics F. CLOSE 11:15 - 12:00 Accelerators (1/5) S. GILARDONI / E. METRAL 12:00 Discussion Session 7/07/2006 09:15 - 11:00 Introduction to Particle Physics F. CLOSE 11:15 - 12:00 Accelerators (2/5) S. GILARDONI / E. METRAL 12:00 Discussion Session 09:15 - 10:00 Accelerators (3/5) S. GILARDONI / E. METRAL 10:15 - 12:00 Detectors (1-2/5) O. ULLALAND 12:00 Discussion Session 11/07/2006 09:15 - 10:00 Accelerators (4/5) S. GILARDONI / E. METRAL 10:15 - 11:00 Detectors (3/5) O. ULLALAND 11:15 - 12:00 Introduction to Nuclear Physics (1/4) P. CHOMAZ P. CHOMAZ 10:15 - 11:00 Accelerators (5/5) S. GILARDONI / E. METRAL 11:15 - 12:00 Detectors (4/5) O. ULLALAND 12:00 Discus...

  2. Scientific Programme Committee

    Science.gov (United States)

    2013-02-01

    Scientific Programme Committee A. Blondel, University of Geneva A. Cervera, IFIC M. Dracos, IN2P3 I. Efhymiopoulos, CERN J. Ellis, CERN S. Geer, FNAL R. Garoby, CERN M. Goodman, ANL D. Harris, FNAL T. Hasegawa, KEK P. Huber, Virginia Tech. D. Kaplan, IIT Y.D. Kim, Sejong University H. Kirk, BNL Y. Kuno, Osaka University K. Long, Imperial College N.K. Mondal, TIFR J. Morfin, FNAL Y. Mori, Kyoto University K. Nishikawa, KEK V. Palladino, University of Napoli C. Prior, RAL F.J.P. Soler, University of Glasgow J. Strait, FNAL R. Svoboda, University of California Davis F. Terranova, LN Frascati M. Zisman, LBNL Local Organizing Committee E. Benedetto, CERN/NTUA C. Blanchard, University of Geneva A. Blondel, University of Geneva (co-chair) I. Efthymiopoulos, CERN (co-chair) F. Dufour, University of Geneva F. Girard-Madoux, CERN E. Gschwendtner, CERN A. Korzenev, University of Geneva M. Morer-Olafsen, CERN S. Murphy, University of Geneva G. Prior, CERN G. Wikström, University of Geneva E. Wildner, CERN Sponsors EuCARD European Organization for Nuclear Research (CERN) Swiss Institute for Particle Physics (CHIPP) University of Geneva

  3. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Françoise Benz

    2002-01-01

    SUMMER STUDENT LECTURE PROGRAMME Main Auditorium, bldg. 500   DATE TIME LECTURER TITLE Monday 29 July 09:15 - 10:00 R. RATTAZZI Beyond the Standard Model (3/3) 10:15 - 11:00 P. WELLS Experimental test of the SM - LEP (3/3) 11:15 - 12:00 P. WELLS Discussion Session 14:00 - 16:00 R. ASSMANN The CLIC Concept for a Future Particle Collider at the Energy Frontier Tuesday 30 July 09:15 - 10:00 F. ANTINORI Heavy Ions (1/2) 10:15 - 12:00 F. DYDAK Neutrino Physics (1&2/4) Wednesday 31 July  09:15 - 10:00 F. ANTINORI Heavy Ions (2/2) 10:15 - 11:00 F. DYDAK Neutrino Physics (3/4) 11:15 - 12:00 F. DYDAK / F. ANTINORI Discussion Session Thursday 1 August 09:15 - 10:00 T. NAKADA CP Violation (1/4) 10:15 - 11:00 F. DYDAK Neutrino Physics (4/4) 11:15 - 12:00 F. BEDESCHI Experimental test of the SM Tevatron (1/2) Friday 2 August 09:15 - 10:00 T. NAKADA CP Violation (2/4) 10:15 ? 11:00 F. BEDESCHI Experimental test of the SM Tevatron (2/2) 11:15 ? 12:00 F. BEDESCHI / T. NAKADA Di...

  4. ALICE pp physics programme

    CERN Document Server

    Kraus, Ingrid

    2009-01-01

    The physics programme of the ALICE experiment at CERN-LHC comprises besides studies of high-energy heavy-ion collisions measurements of proton-proton interactions at unprecedented energies, too. This paper focuses on the global event characterisation in terms of the multiplicity distribution of charged hadrons and mean transverse momentum. These bulk observables become accessible because the detector features excellent track reconstruction, especially at low transverse momenta. The measurement of strange hadrons is of particular interest since the strange-particle phase-space was found to be suppressed beyond canonical reduction at lower center-of-mass energies and the production mechanism of soft particles is not yet fully understood. Here we benefit in particular from particle identification down to very low transverse momentum, i.e. 100 - 300 MeV/c, giving access to spectra and integrated yields of identified hadrons. Equipped with these features, ALICE will play a complementary role w.r.t. other LHC exper...

  5. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Françoise Benz

    2002-01-01

    Main Auditorium, bldg. 500   DATE TIME LECTURER TITLE Wednesday 3 July 09:15 - 10:00 L. FAYARD, O. ULLALAND Presentation of the Summer Student Programm 10:15 - 12:00 L. MAIANI Introduction to CERN (1&2/2) 14:00 - 15:00 G. Stevenson Radiation Protection (Council Chamber, bldg.503) Thursday 4 July 09:15 - 11:00 F. CLOSE Introduction to Particle Physics for non Physics Students (1&2/4) 11:15 - 12:00 C. JORAM Particle Detectors (1/5) Friday 5 July 09:15 - 11:00 F. CLOSE Introduction to Particle Physics for non Physics Students (3&4/4) 11:15 - 12:00 Discussion Session Monday 8 July 09:15 - 10:00 R. KLEISS Fundamental Concepts of Particle Physics (1/6) 10:15 - 11:00 C. JORAM Particle Detectors (2/5) 11:15 - 12:00 M. FRANKLIN Classic Experiments (1/3) 14:00 - 15:00 M. LINDROOS Isolde 15:30 - 16:30 M. LINDROOS Visit of the Experiment Tuesday 9 july 09:15 - 10:00 R. KLEISS Fundamental Concepts of Particle Physics (2/6) 10:15 - 11:00 C. JORAM Part...

  6. Designing Adult Education Activities: A Case of Civic Education Programmes by National Commission for Civic Education in the Ashaiman Municipality in Ghana

    Science.gov (United States)

    Afriyie, Sally Adwoa

    2015-01-01

    This article discusses the efficiency of the design of educational activities of the National Commission for Civic Education (NCCE) in Ashaiman municipality in Ghana. Using a descriptive case study design, data was collected from seven (7) Community Based Groups in Ashaiman. The results of the study indicated that to a large extent, there was…

  7. Adapted Physical Activity Programme and Self-Perception in Obese Adolescents with Intellectual Disability: Between Morphological Awareness and Positive Illusory Bias

    Science.gov (United States)

    Salaun, Laureline; Reynes, Eric; Berthouze-Aranda, Sophie E.

    2014-01-01

    Background: In adolescents with intellectual disability, the management of obesity is a crucial issue, yet also quite complex because of their particular perception of themselves. This study investigated the relationship between self-perception variables and morphological variables and their changes after a 9-month Adapted Physical Activity (APA)…

  8. The (cost-)effectiveness of an individually tailored long-term worksite health promotion programme on physical activity and nutrition: design of a pragmatic cluster randomised controlled trial

    NARCIS (Netherlands)

    S.J.W. Robroek (Suzan); F.J. Bredt (Folef); A. Burdorf (Alex)

    2007-01-01

    textabstractCardiovascular disease is the leading cause of disability and mortality in most Western countries. The prevalence of several risk factors, most notably low physical activity and poor nutrition, is very high. Therefore, lifestyle behaviour changes are of great importance. The worksite off

  9. Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3 : Area 5)

    NARCIS (Netherlands)

    Bousquet, J; Farrell, J; Crooks, G; Hellings, P; Bel, E H; Bewick, M; Chavannes, N H; de Sousa, J Correia; Cruz, A A; Haahtela, T; Joos, G; Khaltaev, N; Malva, J; Muraro, A; Nogues, M; Palkonen, S; Pedersen, S; Robalo-Cordeiro, C; Samolinski, B; Strandberg, T; Valiulis, A; Yorgancioglu, A; Zuberbier, T; Bedbrook, A; Aberer, W; Adachi, M; Agusti, A; Akdis, C A; Akdis, M; Ankri, J; Alonso, A; Annesi-Maesano, I; Ansotegui, I J; Anto, J M; Arnavielhe, S; Arshad, H; Bai, C; Baiardini, I; Bachert, C; Baigenzhin, A K; Barbara, C; Bateman, E D; Beghé, B; Kheder, A Ben; Bennoor, K S; Benson, M; Bergmann, K C; Bieber, T; Bindslev-Jensen, C; Bjermer, L; Blain, H; Blasi, F; Boner, A L; Bonini, M; Bonini, S; Bosnic-Anticevitch, S; Boulet, L P; Bourret, R; Bousquet, P J; Braido, F; Briggs, A H; Brightling, C E; Brozek, J; Buhl, R; Burney, P G; Bush, A; Caballero-Fonseca, F; Caimmi, D; Calderon, M A; Calverley, P M; Camargos, P A M; Canonica, G W; Camuzat, T; Carlsen, K H; Carr, W; Carriazo, A; Casale, T; Cepeda Sarabia, A M; Chatzi, L; Chen, Y. Z.; Chiron, R; Chkhartishvili, E; Chuchalin, A G; Chung, K F; Ciprandi, G; Cirule, I; Cox, L; Costa, D J; Custovic, A; Dahl, R; Dahlen, S E; Darsow, U; De Carlo, G; De Blay, F; Dedeu, T; Deleanu, D; De Manuel Keenoy, E; Demoly, P; Denburg, J A; Devillier, P; Didier, A; Dinh-Xuan, A T; Djukanovic, R; Dokic, D; Douagui, H; Dray, G; Dubakiene, R; Durham, S R; Dykewicz, M S; El-Gamal, Y; Emuzyte, R; Fabbri, L M; Fletcher, M; Fiocchi, A; Fink Wagner, A; Fonseca, J; Fokkens, W J; Forastiere, F; Frith, P; Gaga, M; Gamkrelidze, A; Garces, J; Garcia-Aymerich, J; Gemicioğlu, B; Gereda, J E; González Diaz, S; Gotua, M; Grisle, I; Grouse, L; Gutter, Z; Guzmán, M A; Heaney, L G; Hellquist-Dahl, B; Henderson, D; Hendry, A; Heinrich, J.; Heve, D; Horak, F; Hourihane, J O' B; Howarth, P; Humbert, M; Hyland, M E; Illario, M; Ivancevich, J C; Jardim, J R; Jares, E J; Jeandel, C; Jenkins, C; Johnston, S L; Jonquet, O; Julge, K; Jung, K S; Just, J; Kaidashev, I; Kaitov, M R; Kalayci, O; Kalyoncu, A F; Keil, T; Keith, P K; Klimek, L; Koffi N'Goran, B; Kolek, V; Koppelman, G H; Kowalski, M L; Kull, I; Kuna, P; Kvedariene, V; Lambrecht, B; Lau, S; Larenas-Linnemann, D; Laune, D; Le, L T T; Lieberman, P; Lipworth, B; Li, J.; Lodrup Carlsen, K; Louis, R; MacNee, W; Magard, Y; Magnan, A; Mahboub, B; Mair, A; Majer, I; Makela, M J; Manning, P; Mara, S; Marshall, G D; Masjedi, M R; Matignon, P; Maurer, M.; Mavale-Manuel, S; Melén, E; Melo-Gomes, E; Meltzer, E O; Menzies-Gow, A; Merk, H.; Michel, J P; Miculinic, N; Mihaltan, F; Milenkovic, B; Mohammad, G M Y; Molimard, M; Momas, I; Montilla-Santana, A; Morais-Almeida, M; Morgan, M; Mösges, R; Mullol, J; Nafti, S; Namazova-Baranova, L; Naclerio, R; Neou, A; Neffen, H; Nekam, K; Niggemann, B; Ninot, G; Nyembue, T D; O'Hehir, R E; Ohta, K; Okamoto, Y; Okubo, K; Ouedraogo, S; Paggiaro, P; Pali-Schöll, I; Panzner, P; Papadopoulos, N; Papi, A; Park, H S; Passalacqua, G; Pavord, I; Pawankar, R; Pengelly, R; Pfaar, O; Picard, R; Pigearias, B; Pin, I; Plavec, D; Poethig, D; Pohl, W; Popov, T A; Portejoie, F; Potter, P; Postma, D; Price, D; Rabe, K F; Raciborski, F; Radier Pontal, F; Repka-Ramirez, S; Reitamo, S; Rennard, S; Rodenas, F; Roberts, J; Roca, J; Rodriguez Mañas, L; Rolland, C; Roman-Rodriguez, M.; Romano, A; Rosado-Pinto, J; Rosario, N; Rosenwasser, L; Rottem, M; Ryan, D.; Sanchez-Borges, M; Scadding, G K; Schunemann, H J; Serrano, E; Schmid-Grendelmeier, P; Schulz, H; Sheikh, A; Shields, M; Siafakas, N; Sibille, Y; Similowski, T; Simons, F E R; Sisul, J C; Skrindo, I; Smit, H. A.; Solé, D; Sooronbaev, T; Spranger, O; Stelmach, R; Sterk, P J; Sunyer, J; Thijs, C.; To, T; Todo-Bom, A; Triggiani, M; Valenta, R; Valero, A L; Valia, E; Valovirta, E; Van Ganse, E; van Hage, M; Vandenplas, O; Vasankari, T; Vellas, B; Vestbo, J; Vezzani, G; Vichyanond, P; Viegi, G; Vogelmeier, C; Vontetsianos, T; Wagenmann, M; Wallaert, B; Walker, S; Wang, D. Y.; Wahn, U; Wickman, M; Williams, D M; Williams, S; Wright, J; Yawn, B P; Yiallouros, P K; Yusuf, O M; Zaidi, A; Zar, H J; Zernotti, M E; Zhang, L.; Zhong, N; Zidarn, M; Mercier, J

    2016-01-01

    Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS

  10. Designing Adult Education Activities: A Case of Civic Education Programmes by National Commission for Civic Education in the Ashaiman Municipality in Ghana

    Science.gov (United States)

    Afriyie, Sally Adwoa

    2015-01-01

    This article discusses the efficiency of the design of educational activities of the National Commission for Civic Education (NCCE) in Ashaiman municipality in Ghana. Using a descriptive case study design, data was collected from seven (7) Community Based Groups in Ashaiman. The results of the study indicated that to a large extent, there was…

  11. Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3

    DEFF Research Database (Denmark)

    Bousquet, J; Farrell, J; Crooks, G;

    2016-01-01

    Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS ...

  12. "This Choice Thing Really Works?…?" Changes in Experiences and Engagement of Adolescent Girls in Physical Education Classes, during a School-Based Physical Activity Programme

    Science.gov (United States)

    Mitchell, Fiona; Gray, Shirley; Inchley, Jo

    2015-01-01

    Background: There is a significant amount of research which shows a proportion of girls are not engaging with physical education (PE) in school, resulting in a number of relatively inactive girls within the PE class. These girls are often identified in the literature as "low active", "hard to reach" or "disengaged".…

  13. Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).

    Science.gov (United States)

    Bousquet, J; Farrell, J; Crooks, G; Hellings, P; Bel, E H; Bewick, M; Chavannes, N H; de Sousa, J Correia; Cruz, A A; Haahtela, T; Joos, G; Khaltaev, N; Malva, J; Muraro, A; Nogues, M; Palkonen, S; Pedersen, S; Robalo-Cordeiro, C; Samolinski, B; Strandberg, T; Valiulis, A; Yorgancioglu, A; Zuberbier, T; Bedbrook, A; Aberer, W; Adachi, M; Agusti, A; Akdis, C A; Akdis, M; Ankri, J; Alonso, A; Annesi-Maesano, I; Ansotegui, I J; Anto, J M; Arnavielhe, S; Arshad, H; Bai, C; Baiardini, I; Bachert, C; Baigenzhin, A K; Barbara, C; Bateman, E D; Beghé, B; Kheder, A Ben; Bennoor, K S; Benson, M; Bergmann, K C; Bieber, T; Bindslev-Jensen, C; Bjermer, L; Blain, H; Blasi, F; Boner, A L; Bonini, M; Bonini, S; Bosnic-Anticevitch, S; Boulet, L P; Bourret, R; Bousquet, P J; Braido, F; Briggs, A H; Brightling, C E; Brozek, J; Buhl, R; Burney, P G; Bush, A; Caballero-Fonseca, F; Caimmi, D; Calderon, M A; Calverley, P M; Camargos, P A M; Canonica, G W; Camuzat, T; Carlsen, K H; Carr, W; Carriazo, A; Casale, T; Cepeda Sarabia, A M; Chatzi, L; Chen, Y Z; Chiron, R; Chkhartishvili, E; Chuchalin, A G; Chung, K F; Ciprandi, G; Cirule, I; Cox, L; Costa, D J; Custovic, A; Dahl, R; Dahlen, S E; Darsow, U; De Carlo, G; De Blay, F; Dedeu, T; Deleanu, D; De Manuel Keenoy, E; Demoly, P; Denburg, J A; Devillier, P; Didier, A; Dinh-Xuan, A T; Djukanovic, R; Dokic, D; Douagui, H; Dray, G; Dubakiene, R; Durham, S R; Dykewicz, M S; El-Gamal, Y; Emuzyte, R; Fabbri, L M; Fletcher, M; Fiocchi, A; Fink Wagner, A; Fonseca, J; Fokkens, W J; Forastiere, F; Frith, P; Gaga, M; Gamkrelidze, A; Garces, J; Garcia-Aymerich, J; Gemicioğlu, B; Gereda, J E; González Diaz, S; Gotua, M; Grisle, I; Grouse, L; Gutter, Z; Guzmán, M A; Heaney, L G; Hellquist-Dahl, B; Henderson, D; Hendry, A; Heinrich, J; Heve, D; Horak, F; Hourihane, J O' B; Howarth, P; Humbert, M; Hyland, M E; Illario, M; Ivancevich, J C; Jardim, J R; Jares, E J; Jeandel, C; Jenkins, C; Johnston, S L; Jonquet, O; Julge, K; Jung, K S; Just, J; Kaidashev, I; Kaitov, M R; Kalayci, O; Kalyoncu, A F; Keil, T; Keith, P K; Klimek, L; Koffi N'Goran, B; Kolek, V; Koppelman, G H; Kowalski, M L; Kull, I; Kuna, P; Kvedariene, V; Lambrecht, B; Lau, S; Larenas-Linnemann, D; Laune, D; Le, L T T; Lieberman, P; Lipworth, B; Li, J; Lodrup Carlsen, K; Louis, R; MacNee, W; Magard, Y; Magnan, A; Mahboub, B; Mair, A; Majer, I; Makela, M J; Manning, P; Mara, S; Marshall, G D; Masjedi, M R; Matignon, P; Maurer, M; Mavale-Manuel, S; Melén, E; Melo-Gomes, E; Meltzer, E O; Menzies-Gow, A; Merk, H; Michel, J P; Miculinic, N; Mihaltan, F; Milenkovic, B; Mohammad, G M Y; Molimard, M; Momas, I; Montilla-Santana, A; Morais-Almeida, M; Morgan, M; Mösges, R; Mullol, J; Nafti, S; Namazova-Baranova, L; Naclerio, R; Neou, A; Neffen, H; Nekam, K; Niggemann, B; Ninot, G; Nyembue, T D; O'Hehir, R E; Ohta, K; Okamoto, Y; Okubo, K; Ouedraogo, S; Paggiaro, P; Pali-Schöll, I; Panzner, P; Papadopoulos, N; Papi, A; Park, H S; Passalacqua, G; Pavord, I; Pawankar, R; Pengelly, R; Pfaar, O; Picard, R; Pigearias, B; Pin, I; Plavec, D; Poethig, D; Pohl, W; Popov, T A; Portejoie, F; Potter, P; Postma, D; Price, D; Rabe, K F; Raciborski, F; Radier Pontal, F; Repka-Ramirez, S; Reitamo, S; Rennard, S; Rodenas, F; Roberts, J; Roca, J; Rodriguez Mañas, L; Rolland, C; Roman Rodriguez, M; Romano, A; Rosado-Pinto, J; Rosario, N; Rosenwasser, L; Rottem, M; Ryan, D; Sanchez-Borges, M; Scadding, G K; Schunemann, H J; Serrano, E; Schmid-Grendelmeier, P; Schulz, H; Sheikh, A; Shields, M; Siafakas, N; Sibille, Y; Similowski, T; Simons, F E R; Sisul, J C; Skrindo, I; Smit, H A; Solé, D; Sooronbaev, T; Spranger, O; Stelmach, R; Sterk, P J; Sunyer, J; Thijs, C; To, T; Todo-Bom, A; Triggiani, M; Valenta, R; Valero, A L; Valia, E; Valovirta, E; Van Ganse, E; van Hage, M; Vandenplas, O; Vasankari, T; Vellas, B; Vestbo, J; Vezzani, G; Vichyanond, P; Viegi, G; Vogelmeier, C; Vontetsianos, T; Wagenmann, M; Wallaert, B; Walker, S; Wang, D Y; Wahn, U; Wickman, M; Williams, D M; Williams, S; Wright, J; Yawn, B P; Yiallouros, P K; Yusuf, O M; Zaidi, A; Zar, H J; Zernotti, M E; Zhang, L; Zhong, N; Zidarn, M; Mercier, J

    2016-01-01

    Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS integrated care pathways (ICPs), (2) the joint initiative between the Reference site MACVIA-LR (Contre les MAladies Chroniques pour un VIeillissement Actif) and ARIA (Allergic Rhinitis and its Impact on Asthma), (3) Commitments for Action to the European Innovation Partnership on Active and Healthy Ageing and the AIRWAYS ICPs network. It is deployed in collaboration with the World Health Organization Global Alliance against Chronic Respiratory Diseases (GARD). The European Innovation Partnership on Active and Healthy Ageing has proposed a 5-step framework for developing an individual scaling up strategy: (1) what to scale up: (1-a) databases of good practices, (1-b) assessment of viability of the scaling up of good practices, (1-c) classification of good practices for local replication and (2) how to scale up: (2-a) facilitating partnerships for scaling up, (2-b) implementation of key success factors and lessons learnt, including emerging technologies for individualised and predictive medicine. This strategy has already been applied to the chronic respiratory disease action plan of the European Innovation Partnership on Active and Healthy Ageing.

  14. Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3 : Area 5)

    NARCIS (Netherlands)

    Bousquet, J; Farrell, J; Crooks, G; Hellings, P; Bel, E H; Bewick, M; Chavannes, N H; de Sousa, J Correia; Cruz, A A; Haahtela, T; Joos, G; Khaltaev, N; Malva, J; Muraro, A; Nogues, M; Palkonen, S; Pedersen, S; Robalo-Cordeiro, C; Samolinski, B; Strandberg, T; Valiulis, A; Yorgancioglu, A; Zuberbier, T; Bedbrook, A; Aberer, W; Adachi, M; Agusti, A; Akdis, C A; Akdis, M; Ankri, J; Alonso, A; Annesi-Maesano, I; Ansotegui, I J; Anto, J M; Arnavielhe, S; Arshad, H; Bai, C; Baiardini, I; Bachert, C; Baigenzhin, A K; Barbara, C; Bateman, E D; Beghé, B; Kheder, A Ben; Bennoor, K S; Benson, M; Bergmann, K C; Bieber, T; Bindslev-Jensen, C; Bjermer, L; Blain, H; Blasi, F; Boner, A L; Bonini, M; Bonini, S; Bosnic-Anticevitch, S; Boulet, L P; Bourret, R; Bousquet, P J; Braido, F; Briggs, A H; Brightling, C E; Brozek, J; Buhl, R; Burney, P G; Bush, A; Caballero-Fonseca, F; Caimmi, D; Calderon, M A; Calverley, P M; Camargos, P A M; Canonica, G W; Camuzat, T; Carlsen, K H; Carr, W; Carriazo, A; Casale, T; Cepeda Sarabia, A M; Chatzi, L; Chen, Y. Z.; Chiron, R; Chkhartishvili, E; Chuchalin, A G; Chung, K F; Ciprandi, G; Cirule, I; Cox, L; Costa, D J; Custovic, A; Dahl, R; Dahlen, S E; Darsow, U; De Carlo, G; De Blay, F; Dedeu, T; Deleanu, D; De Manuel Keenoy, E; Demoly, P; Denburg, J A; Devillier, P; Didier, A; Dinh-Xuan, A T; Djukanovic, R; Dokic, D; Douagui, H; Dray, G; Dubakiene, R; Durham, S R; Dykewicz, M S; El-Gamal, Y; Emuzyte, R; Fabbri, L M; Fletcher, M; Fiocchi, A; Fink Wagner, A; Fonseca, J; Fokkens, W J; Forastiere, F; Frith, P; Gaga, M; Gamkrelidze, A; Garces, J; Garcia-Aymerich, J; Gemicioğlu, B; Gereda, J E; González Diaz, S; Gotua, M; Grisle, I; Grouse, L; Gutter, Z; Guzmán, M A; Heaney, L G; Hellquist-Dahl, B; Henderson, D; Hendry, A; Heinrich, J.; Heve, D; Horak, F; Hourihane, J O' B; Howarth, P; Humbert, M; Hyland, M E; Illario, M; Ivancevich, J C; Jardim, J R; Jares, E J; Jeandel, C; Jenkins, C; Johnston, S L; Jonquet, O; Julge, K; Jung, K S; Just, J; Kaidashev, I; Kaitov, M R; Kalayci, O; Kalyoncu, A F; Keil, T; Keith, P K; Klimek, L; Koffi N'Goran, B; Kolek, V; Koppelman, G H; Kowalski, M L; Kull, I; Kuna, P; Kvedariene, V; Lambrecht, B; Lau, S; Larenas-Linnemann, D; Laune, D; Le, L T T; Lieberman, P; Lipworth, B; Li, J.; Lodrup Carlsen, K; Louis, R; MacNee, W; Magard, Y; Magnan, A; Mahboub, B; Mair, A; Majer, I; Makela, M J; Manning, P; Mara, S; Marshall, G D; Masjedi, M R; Matignon, P; Maurer, M.; Mavale-Manuel, S; Melén, E; Melo-Gomes, E; Meltzer, E O; Menzies-Gow, A; Merk, H.; Michel, J P; Miculinic, N; Mihaltan, F; Milenkovic, B; Mohammad, G M Y; Molimard, M; Momas, I; Montilla-Santana, A; Morais-Almeida, M; Morgan, M; Mösges, R; Mullol, J; Nafti, S; Namazova-Baranova, L; Naclerio, R; Neou, A; Neffen, H; Nekam, K; Niggemann, B; Ninot, G; Nyembue, T D; O'Hehir, R E; Ohta, K; Okamoto, Y; Okubo, K; Ouedraogo, S; Paggiaro, P; Pali-Schöll, I; Panzner, P; Papadopoulos, N; Papi, A; Park, H S; Passalacqua, G; Pavord, I; Pawankar, R; Pengelly, R; Pfaar, O; Picard, R; Pigearias, B; Pin, I; Plavec, D; Poethig, D; Pohl, W; Popov, T A; Portejoie, F; Potter, P; Postma, D; Price, D; Rabe, K F; Raciborski, F; Radier Pontal, F; Repka-Ramirez, S; Reitamo, S; Rennard, S; Rodenas, F; Roberts, J; Roca, J; Rodriguez Mañas, L; Rolland, C; Roman-Rodriguez, M.; Romano, A; Rosado-Pinto, J; Rosario, N; Rosenwasser, L; Rottem, M; Ryan, D.; Sanchez-Borges, M; Scadding, G K; Schunemann, H J; Serrano, E; Schmid-Grendelmeier, P; Schulz, H; Sheikh, A; Shields, M; Siafakas, N; Sibille, Y; Similowski, T; Simons, F E R; Sisul, J C; Skrindo, I; Smit, H. A.; Solé, D; Sooronbaev, T; Spranger, O; Stelmach, R; Sterk, P J; Sunyer, J; Thijs, C.; To, T; Todo-Bom, A; Triggiani, M; Valenta, R; Valero, A L; Valia, E; Valovirta, E; Van Ganse, E; van Hage, M; Vandenplas, O; Vasankari, T; Vellas, B; Vestbo, J; Vezzani, G; Vichyanond, P; Viegi, G; Vogelmeier, C; Vontetsianos, T; Wagenmann, M; Wallaert, B; Walker, S; Wang, D. Y.; Wahn, U; Wickman, M; Williams, D M; Williams, S; Wright, J; Yawn, B P; Yiallouros, P K; Yusuf, O M; Zaidi, A; Zar, H J; Zernotti, M E; Zhang, L.; Zhong, N; Zidarn, M; Mercier, J

    2016-01-01

    Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS int

  15. Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3 Area 5)

    NARCIS (Netherlands)

    Bousquet, J; Farrell, J; Crooks, G; Hellings, P; Bel, E H; Bewick, M; Chavannes, N H; de Sousa, J Correia; Cruz, A A; Haahtela, T; Joos, G; Khaltaev, N; Malva, J; Muraro, A; Nogues, M; Palkonen, S; Pedersen, S; Robalo-Cordeiro, C; Samolinski, B; Strandberg, T; Valiulis, A; Yorgancioglu, A; Zuberbier, T; Bedbrook, A; Aberer, W; Adachi, M; Agusti, A; Akdis, C A; Akdis, M; Ankri, J; Alonso, A; Annesi-Maesano, I; Ansotegui, I J; Anto, J M; Arnavielhe, S; Arshad, H; Bai, C; Baiardini, I; Bachert, C; Baigenzhin, A K; Barbara, C; Bateman, E D; Beghé, B; Kheder, A Ben; Bennoor, K S; Benson, M; Bergmann, K C; Bieber, T; Bindslev-Jensen, C; Bjermer, L; Blain, H; Blasi, F; Boner, A L; Bonini, M; Bonini, S; Bosnic-Anticevitch, S; Boulet, L P; Bourret, R; Bousquet, P J; Braido, F; Briggs, A H; Brightling, C E; Brozek, J; Buhl, R; Burney, P G; Bush, A; Caballero-Fonseca, F; Caimmi, D; Calderon, M A; Calverley, P M; Camargos, P A M; Canonica, G W; Camuzat, T; Carlsen, K H; Carr, W; Carriazo, A; Casale, T; Cepeda Sarabia, A M; Chatzi, L; Chen, Y Z; Chiron, R; Chkhartishvili, E; Chuchalin, A G; Chung, K F; Ciprandi, G; Cirule, I; Cox, L; Costa, D J; Custovic, A; Dahl, R; Dahlen, S E; Darsow, U; De Carlo, G; De Blay, F; Dedeu, T; Deleanu, D; De Manuel Keenoy, E; Demoly, P; Denburg, J A; Devillier, P; Didier, A; Dinh-Xuan, A T; Djukanovic, R; Dokic, D; Douagui, H; Dray, G; Dubakiene, R; Durham, S R; Dykewicz, M S; El-Gamal, Y; Emuzyte, R; Fabbri, L M; Fletcher, M; Fiocchi, A; Fink Wagner, A; Fonseca, J; Fokkens, W J; Forastiere, F; Frith, P; Gaga, M; Gamkrelidze, A; Garces, J; Garcia-Aymerich, J; Gemicioğlu, B; Gereda, J E; González Diaz, S; Gotua, M; Grisle, I; Grouse, L; Gutter, Z; Guzmán, M A; Heaney, L G; Hellquist-Dahl, B; Henderson, D; Hendry, A; Heinrich, J; Heve, D; Horak, F; Hourihane, J O' B; Howarth, P; Humbert, M; Hyland, M E; Illario, M; Ivancevich, J C; Jardim, J R; Jares, E J; Jeandel, C; Jenkins, C; Johnston, S L; Jonquet, O; Julge, K; Jung, K S; Just, J; Kaidashev, I; Kaitov, M R; Kalayci, O; Kalyoncu, A F; Keil, T; Keith, P K; Klimek, L; Koffi N'Goran, B; Kolek, V; Koppelman, G H; Kowalski, M L; Kull, I; Kuna, P; Kvedariene, V; Lambrecht, B; Lau, S; Larenas-Linnemann, D; Laune, D; Le, L T T; Lieberman, P; Lipworth, B; Li, J; Lodrup Carlsen, K; Louis, R; MacNee, W; Magard, Y; Magnan, A; Mahboub, B; Mair, A; Majer, I; Makela, M J; Manning, P; Mara, S; Marshall, G D; Masjedi, M R; Matignon, P; Maurer, M; Mavale-Manuel, S; Melén, E; Melo-Gomes, E; Meltzer, E O; Menzies-Gow, A; Merk, H; Michel, J P; Miculinic, N; Mihaltan, F; Milenkovic, B; Mohammad, G M Y; Molimard, M; Momas, I; Montilla-Santana, A; Morais-Almeida, M; Morgan, M; Mösges, R; Mullol, J; Nafti, S; Namazova-Baranova, L; Naclerio, R; Neou, A; Neffen, H; Nekam, K; Niggemann, B; Ninot, G; Nyembue, T D; O'Hehir, R E; Ohta, K; Okamoto, Y; Okubo, K; Ouedraogo, S; Paggiaro, P; Pali-Schöll, I; Panzner, P; Papadopoulos, N; Papi, A; Park, H S; Passalacqua, G; Pavord, I; Pawankar, R; Pengelly, R; Pfaar, O; Picard, R; Pigearias, B; Pin, I; Plavec, D; Poethig, D; Pohl, W; Popov, T A; Portejoie, F; Potter, P; Postma, D.; Price, D; Rabe, K F; Raciborski, F; Radier Pontal, F; Repka-Ramirez, S; Reitamo, S; Rennard, S; Rodenas, F; Roberts, J; Roca, J; Rodriguez Mañas, L; Rolland, C; Roman Rodriguez, M; Romano, A; Rosado-Pinto, J; Rosario, N; Rosenwasser, L; Rottem, M; Ryan, D; Sanchez-Borges, M; Scadding, G K; Schunemann, H J; Serrano, E; Schmid-Grendelmeier, P; Schulz, H; Sheikh, A; Shields, M; Siafakas, N; Sibille, Y; Similowski, T; Simons, F E R; Sisul, J C; Skrindo, I; Smit, H A; Solé, D; Sooronbaev, T; Spranger, O; Stelmach, R; Sterk, P J; Sunyer, J; Thijs, C; To, T; Todo-Bom, A; Triggiani, M; Valenta, R; Valero, A L; Valia, E; Valovirta, E; Van Ganse, E; van Hage, M; Vandenplas, O; Vasankari, T; Vellas, B; Vestbo, J; Vezzani, G; Vichyanond, P; Viegi, G; Vogelmeier, C; Vontetsianos, T; Wagenmann, M; Wallaert, B; Walker, S; Wang, D Y; Wahn, U; Wickman, M; Williams, D M; Williams, S; Wright, J; Yawn, B P; Yiallouros, P K; Yusuf, O M; Zaidi, A; Zar, H J; Zernotti, M E; Zhang, L; Zhong, N; Zidarn, M; Mercier, J

    2016-01-01

    Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS int

  16. Depository libraries in the 21st Century: recasting the ILO programme

    OpenAIRE

    Niimi, Keiko; Furer-Benedetti, Michèle; Corpataux, Yves

    2016-01-01

    Institutions established depository library programmes to ensure universal access to specified documentation. Access to depository materials has traditionally been physical, requiring publishing, dispatching, cataloguing and shelving of documents. With the global shift from print to online availability of material, institutions are questioning whether their depository library programmes have become redundant. Are depository schemes anachronistic when the public can access documents directly v...

  17. Academic Programmes in Universities in East Africa: A Catalyst to Development

    Science.gov (United States)

    Karimi, Florah Katanu

    2015-01-01

    The types of academic programmes offered by universities, both public and private, are considered to be critical to the realization of development agendas. This study was descriptive in nature and sought to establish whether universities in the East African region were offering academic programmes that were relevant to the realization of the…

  18. Predicting the risk of a false-positive test for women following a mammography screening programme

    DEFF Research Database (Denmark)

    Njor, Sisse Helle; Olsen, Anne Helene; Schwartz, Walter

    2007-01-01

    OBJECTIVES: The objectives of this study was to provide a simple estimate of the cumulative risk of a false-positive test for women participating in mammography screening. To test the method, we used data from two well-established, organized mammography screening programmes offering biennial...... be calculated in a simple way relatively early after the start of a mammography screening programme....

  19. Curriculum Assessment as a Direct Tool in ABET Outcomes Assessment in a Chemical Engineering Programme

    Science.gov (United States)

    Abu-Jdayil, Basim; Al-Attar, Hazim

    2010-01-01

    The chemical engineering programme at the United Arab Emirates University is designed to fulfil the Accreditation Board for Engineering and Technology (ABET) (A-K) EC2000 criteria. The Department of Chemical & Petroleum Engineering has established a well-defined process for outcomes assessment for the chemical engineering programme in order to…

  20. Chinese integrative medicine:inclusion of a Chinese medicine programme in a conventional medical institute

    Institute of Scientific and Technical Information of China (English)

    Hai-Yong Chen; Yibin Feng; Lixing Lao

    2014-01-01

    To meet community demands with optimal Chinese and conventional medical treatment, the University of Hong Kong is promoting integrative medicine by developing Chinese medicine programmes that train students of both Western and Chinese medicine. The programmes emphasize multi-disciplinary training and interaction between the two therapeutic approaches, enabling students to establish reliable, consistent, and respectful mutual cooperation in their future careers.

  1. Professor Claude Detraz, Director for fixed target and future programmes

    CERN Multimedia

    Patrice Loïez

    2003-01-01

    Four of them came under the newly established collaboration agreement between CERN (Prof. Claude Detraz) and NTU (Prof. Evangelos Gazis), prepared by Dr. Magda Lola (CERN-Recruitment Service), for the training of students at the Laboratory, while two more are participants to the standard CERN Summer Students Programme.

  2. Tony’s influence on the music therapy doctoral programme

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner

    2011-01-01

    The first important initiatives to establish international collaboration in music therapy research were taken in 1995 by Inge Nygaard Pedersen, Lars Ole Bonde and Tony Wigram. In 1997 Tony was given the task of leading, developing and creating a doctoral programme. The faculty of humanities granted...

  3. DANIDA; Air Quality Monitoring Programme. Mission 3 Report

    Energy Technology Data Exchange (ETDEWEB)

    Sivertsen, B.; Marsteen, L.

    1996-12-31

    In the development of the Environmental Information and Monitoring Programme for the Arab Republic of Egypt (EIMP), NILU is responsible for the establishment of an air pollution monitoring system. This report summarizes the third mission to Egypt and includes meetings and site visit reports. Air quality sites in Alexandria are described and comments are given to earlier selected sites in Cairo

  4. Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).

    OpenAIRE

    Bousquet, J.; Farrell, J.; Crooks, G.; Hellings, P; Bel, E. H.; Bewick, M; Chavannes, N H; de Sousa, J. Correia; Cruz, A A; Haahtela, T.; Joos, G.; Didier, A.; Dinh-Xuan, A. T.; Djukanovic, R.; Dokic, D.

    2016-01-01

    Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS integrated care pathways (ICPs), (2) the joint initiative between the Reference site MACVIA-LR (Contre les MAladies Chroniques pour un VIeillissement Actif) and ARIA (Allergic Rhinitis and its Impact ...

  5. Changes in experiences and engagement of adolescent girls in Physical Education classes, during a school-based physical activity programme : a qualitative longitudinal study.

    OpenAIRE

    Mitchell, Fiona

    2012-01-01

    There is a growing body of literature investigating age-related declines in physical activity (PA) participation among young people and especially girls, who have lower rates of PA than boys throughout the teenage years. Low PA is particularly apparent within the context of the school physical education classes – termed here as the Physical Education (PE) environment. My PhD thesis aims to explore the reasons for some girls disengagement in PE classes. Using a longitudina...

  6. The IDEFICS Community-Oriented Intervention Programme

    DEFF Research Database (Denmark)

    De Henauw, Stefaan; Verbestel, V.; Mårild, Staffan

    2011-01-01

    levels of society, with the aim of facilitating the adoption of a healthy obesity-preventing lifestyle. The overall programme has been composed of 10 modules: three at community level, six at school level and one for parents. The main focus was on diet, physical activity and stress-coping capacity......Background and objectives: The European Union—as well as other parts of the world—faces a major challenge of increasing incidence of overweight/obesity. In particular, the increase in childhood obesity gives rise to a strong imperative for immediate action. Yet, little is known about...... to develop new pathways for sustainable health-promoting communities. Against this background, the IDEFICS (Identification and prevention of dietary- and lifestyle-induced health effects in children and infants) study developed and implemented innovative community-oriented intervention programmes for obesity...

  7. Establishing effective working relationships.

    Science.gov (United States)

    Houghton, Trish

    2016-02-24

    This article, the second in a series of 11, provides support and offers advice to new and existing mentors and practice teachers to enable them to progress in their role and develop a portfolio of evidence. In particular, the article discusses how to establish effective working relationships and emphasises the importance of the student-mentor or student-practice teacher relationship. It examines the essential qualities, attributes and characteristics of an effective mentor or practice teacher. The article provides learning activities and suggests ways in which mentors and practice teachers can undertake various self-assessments, enabling them to gather relevant evidence to demonstrate how they can meet and maintain the requirements for these roles as stipulated by the Nursing and Midwifery Council.

  8. Post Graduate Programme in Dietetics & Food Service Management (MSCDFSM) Programme of IGNOU: Access through the Lucknow Regional Centre

    Science.gov (United States)

    Dorothy, J. S.; Kumar, Ashwini

    2014-01-01

    Indira Gandhi National Open University (IGNOU) which was established initially as a Single mode Distance Teaching Institution (DTI) in the year 1985 opened its campus to face-to-face education in the year 2008 and thus now is a Dual mode Distance Teaching Institution (DTI). The Post Graduate Programme (Master of Science) in Dietetics and Food…

  9. Strategic planning of the master programme in health informatics at Aalborg University: targeting and updating the programme, to meet explicit customer needs.

    Science.gov (United States)

    Nøhr, C; Bygholm, A; Hejlesen, O

    1998-06-01

    Education is essentially giving people new skills and qualifications to fulfil certain tasks. In planning and managing educational programmes it is crucial to know what skills and what qualifications are needed to carry out the tasks in question, not to mention the importance of knowing what tasks are relevant to carry out. The programme in health informatics at Aalborg University produces health informatics professionals. The students are developing skills in solving informatics problems in health care organisations. The programme has been running for 3 years now and to maintain the perception of the aim for the programme a number of activities have been launched. In the following, the programme will be presented, the activities to obtain information on how to keep the programme targeted and updated will be described and the changes that are going to be introduced will be outlined.

  10. Abandoning weight-loss programmes

    African Journals Online (AJOL)

    emphasis on factors relating to reasons why the weight loss programmes had ... the increase according to a National Health and Nutrition .... classes after weight gain. 7. 14. 26 .... 'slow metabolism' (8%), and a chronic problem of premenstrual.

  11. CERN openlab summer student programme

    CERN Multimedia

    2013-01-01

    CERN openlab is currently taking applications for its summer student programme. The closing date for applications is 31 March 2013.   The openlab summer student programme is open for applications from bachelor, master and PhD students in computer science and physics. Successful applicants will spend 9 weeks at CERN, during the period from June to September 2013, working with some of the latest hardware and software technologies. The programme is more than just a summer at CERN: it can lead to follow-on projects at the home institute and may even inspire students to become entrepreneurs in cutting-edge computing technologies. A series of lectures will be given by experts in various domains of CERN-related high-throughput computing. Study tours of external companies and universities as well as of CERN facilities are also part of the programme. Please visit the CERN openlab website for more information.

  12. CERN openlab Summer Student Programme

    CERN Multimedia

    2012-01-01

    CERN openlab is currently taking applications for its summer student programme. The closing date for applications is 30 March 2012.   The openlab Summer Student Programme is open for applications from bachelor, master and PhD students in computer science and physics. Successful applicants will spend 8 weeks at CERN, during the period June to September 2012, to work with some of the latest hardware and software technologies. The programme is more than just a summer at CERN: it can lead to follow-on projects at the home institute and may even inspire the students to become entrepreneurs in cutting-edge computing technologies. A series of lectures will be given by experts in various domains of CERN related high-throughput computing. Study tours to external companies and universities as well as to CERN facilities are also part of the programme. Please visit www.cern.ch/openlab-students for more information.

  13. A Novel Processor Scheduling Schema in Programmable Router Based on Queue Length Thresholds

    Institute of Scientific and Technical Information of China (English)

    Xu Ke(徐恪); Lin Chuang; Wu Jianping

    2004-01-01

    Programmable router may execute computing tasks except for forwarding IP packets. How to schedule the CPU in the programmable router is an important issue that needs to be solved. In this paper, the authors establish general software architecture of programmable router firstly. Based on this architecture, authors present a novel CPU scheduling algorithm based on queue length thresholds. We model this algorithm using stochastic Petri nets. The analytic results show that this scheduling algorithm can guarantee the requirements of computing of best-effort flows and QoS flows in programmable router at the same time.

  14. Experimental programs; Programmes experimentaux

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-10-01

    The aim of this Workshop is to establish the status of the experiments for transmutation demonstration and assessment, especially for innovative options and accelerator driven systems (ADS), to establish the results expected to be available for 2006 and to indicate the needs, and to exchange information on experiments. Only one communication is available and concerns the PROFIL irradiation experiments performed with the Phenix reactor. In these experiments, isotopes are separately set in a fuel needle which is placed in a fuel assembly close to the core centre. Samples are analyzed after irradiation in order to determine their variation of composition. These experiments supply precious information about basic nuclear data (capture, fission, n,2n and branching factors) with limited uncertainties. (J.S.)

  15. Field Evaluation of Programmable Thermostats

    Energy Technology Data Exchange (ETDEWEB)

    Sachs, O. [Fraunhofer Center for Sustainable Energy Systems (CSE), Cambridge, MA (United States); Tiefenbeck, V. [Fraunhofer Center for Sustainable Energy Systems (CSE), Cambridge, MA (United States); Duvier, C. [Fraunhofer Center for Sustainable Energy Systems (CSE), Cambridge, MA (United States); Qin, A. [Fraunhofer Center for Sustainable Energy Systems (CSE), Cambridge, MA (United States); Cheney, K. [Fraunhofer Center for Sustainable Energy Systems (CSE), Cambridge, MA (United States); Akers, C. [Fraunhofer Center for Sustainable Energy Systems (CSE), Cambridge, MA (United States); Roth, K. [Fraunhofer Center for Sustainable Energy Systems (CSE), Cambridge, MA (United States)

    2012-12-01

    Prior research suggests that poor programmable thermostats usability may prevent their effective use to save energy. The Fraunhofer team hypothesized that home occupants with high-usability thermostats would be more likely to use them to save energy than people with a basic thermostats. In this report, the team discusses results of a project in which the team monitored and compared programmable thermostats with basic thermostats in an affordable housing apartment complex.

  16. "Cosmic Vision": the new ESA Science Programme

    Science.gov (United States)

    2002-05-01

    demonstration mission (2006) for LISA, a joint mission with NASA, searching for gravitational waves (2011). In addition the Agency is committed to cooperation with NASA in NGST (the Next Generation Space Telescope), the successor of the Hubble Space telescope, with launch in 2010. STEP (2005), the mission to test of the nature of mass and the basis of mechanics, relies on a decision by NASA, the major partner. The production groups are more than scientific groupings. Missions within each will be built synergistically using common technologies and engineering teams where possible. Such a scenario is going to rely on specific commitment to new ways of working: - The implementation of BepiColombo and Solar Orbiter with international partners. Both missions will be implemented as a single activity, leading to significant savings. - The implementation of Herschel/Planck and Eddington in a single project, re-using the same bus. This implies a launch of Eddington not later than 2008. - Major technical changes reducing the cost of GAIA with no science loss. GAIA will be launched no later than 2012, the date agreed in Bern. - Significant gains through new technology in cost effectiveness of spacecraft development and procurement. - The timely availability of payloads, one of the current pressing problems. - Acceptance of increased managerial complexity and overall programmatic risk. Obviously, the implementation of such an ambitious programme requires full commitment of all involved parties, namely industry, the Executive, the national funding agencies and the scientific community from the start. Initially the Executive had included in its proposal also VENUS EXPRESS, which would have started immediately. However, the Director of the Science Programme felt that the precondition had not been met and decided to withdraw the proposal. The Executive is going to have to keep such an attitude in the future if it is to implement the programme successfully. Increased programmatic risk means

  17. Longer term follow-up on effects of Tailored Physical Activity or Chronic Pain Self-Management Programme on return-to-work

    DEFF Research Database (Denmark)

    Andersen, Lotte Nygaard; Juul-Kristensen, Birgit; Sørensen, Thomas Lund

    2016-01-01

    the reference group as regards return-to-work. Compared with the reference group no other benefits of TPA and CPSMP were evident regarding pain, work ability, kinesiophobia or physical capacity. CONCLUSION: After 11 months TPA, the reference group, and CPSMP show similar patterns of facilitating return-to-work......OBJECTIVE: To evaluate the longer term efficacy of the interventions Tailored Physical Activity (TPA) and Chronic Pain Self-management Program (CPSMP) against a reference group on return-to-work for sick-listed subjects with pain in the back or upper body. DESIGN: A randomized controlled trial...... to work and the co-primary end-point was the duration of the sickness absence period retrieved 11 months after the first day on sick leave. Secondary outcomes were pain level, body mass index, aerobic capacity, work ability and kinesiophobia. RESULTS: TPA and CPSMP were no more effective than...

  18. Norwegian mastitis control programme.

    Science.gov (United States)

    Osterås, O; Sølverød, L

    2009-04-01

    breeding, eradicating bovine virus diarrhoea virus (BVDV) and a better implementation of mastitis prevention programmes.

  19. Norwegian mastitis control programme

    Science.gov (United States)

    2009-01-01

    breeding, eradicating bovine virus diarrhoea virus (BVDV) and a better implementation of mastitis prevention programmes. PMID:22081877

  20. Norwegian mastitis control programme

    Directory of Open Access Journals (Sweden)

    Østerås O

    2009-04-01

    changes in attitude and breeding, eradicating bovine virus diarrhoea virus (BVDV and a better implementation of mastitis prevention programmes.

  1. The GAPS programme with HARPS-N at TNG. VII. Putting exoplanets in the stellar context: magnetic activity and asteroseismology of τ Bootis A

    Science.gov (United States)

    Borsa, F.; Scandariato, G.; Rainer, M.; Bignamini, A.; Maggio, A.; Poretti, E.; Lanza, A. F.; Di Mauro, M. P.; Benatti, S.; Biazzo, K.; Bonomo, A. S.; Damasso, M.; Esposito, M.; Gratton, R.; Affer, L.; Barbieri, M.; Boccato, C.; Claudi, R. U.; Cosentino, R.; Covino, E.; Desidera, S.; Fiorenzano, A. F. M.; Gandolfi, D.; Harutyunyan, A.; Maldonado, J.; Micela, G.; Molaro, P.; Molinari, E.; Pagano, I.; Pillitteri, I.; Piotto, G.; Shkolnik, E.; Silvotti, R.; Smareglia, R.; Southworth, J.; Sozzetti, A.; Stelzer, B.

    2015-06-01

    Aims: We observed the τ Boo system with the HARPS-N spectrograph to test a new observational strategy aimed at jointly studying asteroseismology, the planetary orbit, and star-planet magnetic interaction. Methods: We collected high-cadence observations on 11 nearly consecutive nights and for each night averaged the raw FITS files using a dedicated software. In this way we obtained spectra with a high signal-to-noise ratio, used to study the variation of the Ca ii H&K lines and to have radial velocity values free from stellar oscillations, without losing the oscillations information. We developed a dedicated software to build a new custom mask that we used to refine the radial velocity determination with the HARPS-N pipeline and perform the spectroscopic analysis. Results: We updated the planetary ephemeris and showed the acceleration caused by the stellar binary companion. Our results on the stellar activity variation suggest the presence of a high-latitude plage during the time span of our observations. The correlation between the chromospheric activity and the planetary orbital phase remains unclear. Solar-like oscillations are detected in the radial velocity time series: we estimated asteroseismic quantities and found that they agree well with theoretical predictions. Our stellar model yields an age of 0.9 ± 0.5 Gyr for τ Boo and further constrains the value of the stellar mass to 1.38 ± 0.05 M⊙. Based on observations made with the Italian Telescopio Nazionale Galileo (TNG) operated on the island of La Palma by the Fundacion Galileo Galilei of the INAF at the Spanish Observatorio Roque de los Muchachos of the IAC in the frame of the program Global Architecture of the Planetary Systems (GAPS).Full Table 1 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/578/A64

  2. Educating sexologists in a Danish university hospital in accordance with a Nordic educational programme

    DEFF Research Database (Denmark)

    Rischel, Karen; Kristensen, Ellids

    2005-01-01

    The establishment of an educational programme in sexology in a Danish university hospital is described and an overview of the historical background of the Nordic Association for Clinical Sexology (NACS) and the Nordic educational programme is presented. The Nordic Association for Clinical Sexology...... was founded in 1978. In 2000, agreement was reached on a three-level educational programme for sexologists and identical rules for authorization in the Nordic countries. After analysis of the Nordic educational programme, curricula on levels 1 and 2 as well as logbooks were designed. Employees of the clinic...... with relevant clinical work could enter the programme. Twelve employees entered the programme at different points; one junior doctor graduated in March 2004. The NACS curricula secure a similar standard of authorized Nordic sexologists. The use of specialist teachers from non-Nordic countries links the Nordic...

  3. Fast track concept in the European fusion programme

    Energy Technology Data Exchange (ETDEWEB)

    Bolt, Harald [Max-Planck-Institute for Plasma Physics, Garching (Germany)

    2002-10-01

    Recently an expert meeting regarding a possible acceleration of the fusion programme with a view to energy production ('fast track') was held on the initiative of the EU Research Council. In the course of the discussions about the fast track programme, it has turned out that successful extraction of reactor grade heat and tritium from the blanket modules is essential in the ITER operation. In parallel with ITER, material development using a high intensity neutron source is essential to establish a database for licensing. The operation of a reactor combining DEMO and PROTO generations into a single step could be around 2030. (author)

  4. HES6 drives a critical AR transcriptional programme to induce castration-resistant prostate cancer through activation of an E2F1-mediated cell cycle network

    Science.gov (United States)

    Ramos-Montoya, Antonio; Lamb, Alastair D; Russell, Roslin; Carroll, Thomas; Jurmeister, Sarah; Galeano-Dalmau, Nuria; Massie, Charlie E; Boren, Joan; Bon, Helene; Theodorou, Vasiliki; Vias, Maria; Shaw, Greg L; Sharma, Naomi L; Ross-Adams, Helen; Scott, Helen E; Vowler, Sarah L; Howat, William J; Warren, Anne Y; Wooster, Richard F; Mills, Ian G; Neal, David E

    2014-01-01

    Castrate-resistant prostate cancer (CRPC) is poorly characterized and heterogeneous and while the androgen receptor (AR) is of singular importance, other factors such as c-Myc and the E2F family also play a role in later stage disease. HES6 is a transcription co-factor associated with stem cell characteristics in neural tissue. Here we show that HES6 is up-regulated in aggressive human prostate cancer and drives castration-resistant tumour growth in the absence of ligand binding by enhancing the transcriptional activity of the AR, which is preferentially directed to a regulatory network enriched for transcription factors such as E2F1. In the clinical setting, we have uncovered a HES6-associated signature that predicts poor outcome in prostate cancer, which can be pharmacologically targeted by inhibition of PLK1 with restoration of sensitivity to castration. We have therefore shown for the first time the critical role of HES6 in the development of CRPC and identified its potential in patient-specific therapeutic strategies. PMID:24737870

  5. HES6 drives a critical AR transcriptional programme to induce castration-resistant prostate cancer through activation of an E2F1-mediated cell cycle network.

    Science.gov (United States)

    Ramos-Montoya, Antonio; Lamb, Alastair D; Russell, Roslin; Carroll, Thomas; Jurmeister, Sarah; Galeano-Dalmau, Nuria; Massie, Charlie E; Boren, Joan; Bon, Helene; Theodorou, Vasiliki; Vias, Maria; Shaw, Greg L; Sharma, Naomi L; Ross-Adams, Helen; Scott, Helen E; Vowler, Sarah L; Howat, William J; Warren, Anne Y; Wooster, Richard F; Mills, Ian G; Neal, David E

    2014-05-01

    Castrate-resistant prostate cancer (CRPC) is poorly characterized and heterogeneous and while the androgen receptor (AR) is of singular importance, other factors such as c-Myc and the E2F family also play a role in later stage disease. HES6 is a transcription co-factor associated with stem cell characteristics in neural tissue. Here we show that HES6 is up-regulated in aggressive human prostate cancer and drives castration-resistant tumour growth in the absence of ligand binding by enhancing the transcriptional activity of the AR, which is preferentially directed to a regulatory network enriched for transcription factors such as E2F1. In the clinical setting, we have uncovered a HES6-associated signature that predicts poor outcome in prostate cancer, which can be pharmacologically targeted by inhibition of PLK1 with restoration of sensitivity to castration. We have therefore shown for the first time the critical role of HES6 in the development of CRPC and identified its potential in patient-specific therapeutic strategies.

  6. A reappraisal of the virtues of private sector employment programmes

    DEFF Research Database (Denmark)

    Jensen, Peter; Graversen, Brian Krogh

    In this paper, we evaluate the employment effects of Danish active labour market programmes aimed at welfare benefit recipients. We estimate an econometric model with treatment effects and discrete outcomes and we allow the responses to treatment to vary among observationally identical persons....... The empirical analysis is based on a register-based dataset that gives infor-mation on participation in labour market programmes and subsequent employment. Using a latent variable model, we estimate commonly defined treatment effects, and in particular, the distribution of treatment effects. We do not find any...... significant mean effects of participation in private sector employment programmes compared to participation in other programmes, but we find evidence of heterogeneity in the treatment effects....

  7. Establishment and characterization of melanoma cell line from a xeroderma pigmentosum patient: activation of N-ras at a potential pyrimidine dimer site.

    NARCIS (Netherlands)

    W. Keijzer; M.P. Mulder; J.C.M. Langeveld; E.M.E. Smit (Elisabeth); J.L. Bos; D. Bootsma (Dirk); J.H.J. Hoeijmakers (Jan)

    1989-01-01

    textabstractPatients suffering from the genetic disorder xeroderma pigmentosum (XP) display an extreme sensitivity of their skin to sun (UV) exposure and predisposition to skin cancer due to deficiencies in the excision DNA repair pathway. Here we describe the establishment and characterization of t

  8. The Learning Effects of a Multidisciplinary Professional Development Programme

    Science.gov (United States)

    Visser, Talitha Christine; Coenders, Fer G. M.; Pieters, Jules M.; Terlouw, Cees

    2013-12-01

    Professional development becomes relevant and effective when teachers are actively involved, collaborate, and when it is linked to teachers' daily school practice (Hunzicker in Prof Dev Educ 37:177-179, 2011). Preparation of teachers for a curriculum implementation such as the new subject Nature, Life, and Technology can be done by a professional development programme where teachers are actively involved (Visser et al. 2010). This study evaluates the designed and implemented professional development programme with respect to its effectiveness in terms of degree of teacher learning and development. Effects are evaluated for five learning areas: Instructional strategies, differences in students' prior knowledge, adjustments to the module, assessment methods and instruments, and field trips and guest lectures. Eleven teachers from four different schools participated in two professional development programmes, six teachers in the first professional development programme and five teachers in the programme for the subsequent module. Questionnaires and interviews were used to assess the effects in the different learning areas. The findings show that the professional development programme is a useful venture for teachers' professional growth in different learning areas.

  9. The Mice Drawer System (MDS) Tissue Sharing Programme: effect of space conditions on skin metabolic activity and vascularization and potential impact of radiations in mice.

    Science.gov (United States)

    Nusgens, Betty; Lambert, Charles; Liu, Yi; Cancedda, Ranieri; Tavella, Sara; Ruggiu, Alessandra; Colige, Alain

    morphological and immunochemical analysis aim at investigating dermal and epidermal thickness, number and surface of blood vessels (CD31, VW factor, type IV collagen) and lymphatics (D2-40, Lyve), score of acanthosis and papillomatosis, proliferation index (Ki67), epidermal markers of differentiation and FXIIIa positive dendritic cells. Another fragment of skin is used for measuring water content, total collagen content (hydroxyproline) and total proteoglycans content (uronic acid). A differential extraction procedure allows to quantify the newly synthetized collagen and the progressively more heavily cross-linked colla-gen, the pattern of extraction reflecting the turn-over rate of collagen. Quantitative RT-PCR procedure is used to evaluate the expression of extracellular matrix components (fibrillar and FACIT collagens), the enzymes involved in their postranslational modifications (ADAMTS-2, -3, -14, BMP1, prolylhydroxylase, lysyloxydase), the MMPs and their physiologic activators and inhibitors, proteoglycans of the hyalectans family and the SLRP, hyaluronansynthase, ag-grecanases of the ADAMTS family, and vascular markers (CD31, VEGF-A, -C, -D, VEGF-R1, -R2, -R3, PlGF, NRP1 2, SEMA3). A special attention will be paid to the splice variants of VEGF-A. We recently discovered a new splice variant, VEGF111, lacking exons 5, 6 and 7, bio-logically active and resistant to proteolysis that is specifically induced by genotoxic agents such as radiations. Its expression might reflect an impact of radiations during the long stay of the animals in space environment. Additionally, a genome-wide analysis of gene expression will be performed using DNA microarrays (Affimetrix). Partial results of the analyses under way will be presented. http://www.nasa.gov/missionp ages/station/science/experiments/M DS.html

  10. Saltwell Leak Detector Station Programmable Logic Controller (PLC) Software Configuration Management Plan (SCMP)

    Energy Technology Data Exchange (ETDEWEB)

    WHITE, K.A.

    2000-11-28

    This document provides the procedures and guidelines necessary for computer software configuration management activities during the operation and maintenance phases of the Saltwell Leak Detector Stations as required by HNF-PRO-309, Rev. 1, Computer Software Quality Assurance, Section 2.4, Software Configuration Management. The software configuration management plan (SCMP) integrates technical and administrative controls to establish and maintain technical consistency among requirements, physical configuration, and documentation for the Saltwell Leak Detector Station Programmable Logic Controller (PLC) software during the Hanford application, operations and maintenance. This SCMP establishes the Saltwell Leak Detector Station PLC Software Baseline, status changes to that baseline, and ensures that software meets design and operational requirements and is tested in accordance with their design basis.

  11. Saltwell PIC Skid Programmable Logic Controller (PLC) Software Configuration Management Plan

    Energy Technology Data Exchange (ETDEWEB)

    KOCH, M.R.

    1999-11-16

    This document provides the procedures and guidelines necessary for computer software configuration management activities during the operation and maintenance phases of the Saltwell PIC Skids as required by LMH-PRO-309, Rev. 0, Computer Software Quality Assurance, Section 2.6, Software Configuration Management. The software configuration management plan (SCMP) integrates technical and administrative controls to establish and maintain technical consistency among requirements, physical configuration, and documentation for the Saltwell PIC Skid Programmable Logic Controller (PLC) software during the Hanford application, operations and maintenance. This SCMP establishes the Saltwell PIC Skid PLC Software Baseline, status changes to that baseline, and ensures that software meets design and operational requirements and is tested in accordance with their design basis.

  12. De-Radicalising Prisoners in Nigeria: developing a basic prison based de-radicalisation programme

    Directory of Open Access Journals (Sweden)

    Atta Barkindo

    2016-06-01

    Full Text Available The Nigerian Counter Terrorism Strategy recognised that force alone was not enough to combat violent extremist elements in Nigeria and that a multi-faceted approach was required to counter the threat of violent extremism. The Office of the National Security Advisor (ONSA was tasked with developing an ambitious countering violent extremism (CVE programme consisting of three elements: community-based counter radicalisation; strategic communications; and de-radicalisation. The de-radicalisation element of the CVE programme included establishing a prison based de-radicalisation programme for sentenced and pre-trial prisoners. The challenge facing ONSA and the Nigerian Prisons Service (NPS in setting up the de-radicalisation programme was considerable. Prison conditions were basic; there were no existing offending behaviour programmes on which to build; risk assessment was rudimentary and focussed on escape risk; awareness among staff at all levels of de-radicalisation programmes, their content and how they should be managed, was minimal; specialist staff were in short supply and had no training in running interventions; and resources, both physical and financial, were limited. This paper sets out how ONSA and NPS went about establishing the de-radicalisation programme and describes key elements of that programme, including: creating a supportive operating environment; risk and needs assessment; types of intervention; and programme management and staffing. It highlights the challenges and lessons that can be drawn from the operation of the programme during its first 18 months, which will be of particular interest to low resource, post-conflict and fragile states that are seeking to establish their own basic de-radicalisation programmes.

  13. Perspectives for food research and European collaboration in the European Research Area and the new Framework Programme.

    Science.gov (United States)

    Breslin, L

    2001-08-01

    Since 1987, successive framework programmes have contributed to strengthen European food research through the establishment of networks between research institutions, universities and companies from various European countries. In the FAIR programme (1994-1998), 118 research projects comprising nearly 1,000 participants from the European Union and Associated States have been supported in the food area with a European funding of about [symbol: see text] 108 million. Within the Quality of Life and Management of Living Resources programme (1998-2002), food research is mostly supported within the key action 'food, nutrition and health' with a budget of [symbol: see text] 290 million. After the first four deadlines, 735 eligible research proposals have already been received. Further to their evaluation by a panel of independent experts, 108 proposals have been funded or selected for funding representing a total contribution of about [symbol: see text] 168 million. Among those, several clusters of projects are now running on important topics such as probiotics, coeliac diseases, mycotoxins, GMO, safety and food for the elderly. In addition, technology stimulation measures are largely benefiting SMEs to foster their innovation potential. In January 2000, the European Commission adopted a Communication entitled "Towards the European Research Area (ERA)" with the objective to contribute to developing better framework conditions for research in Europe. On 21 February 2001, the Commission adopted proposals to be submitted to the European Parliament and Council for the next framework programme for research and innovation (2002-2006). The new framework programme that is becoming one of the financial instruments of the ERA aims at catalysing the integration of European research by: strengthening of links between the Community research effort and national and regional research policies; concentrating on a limited number of priority fields or research to which activities at the

  14. Determination of plateau slope and activity using filter measurement results and W. Chauvenet's criterion (Mage II and Fortran IV calculation programmes); Determination de pente de palier et d'activite a partir de resultats de mesure filtres selon le critere de W. Chauvenet (programmes de calcul en Mage II et Fortran IV)

    Energy Technology Data Exchange (ETDEWEB)

    Becker, A. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires, Departement d' Electronique Generale, Laboratoire de Metrologie de la Radioactivite

    1967-10-01

    In order to permit (at least partially) the objective comparison of plateau characteristics of gas-ionisation counters, plateaus which are obtained when each radioactive sample from normal LMR production is measured, a programme has been drawn up (on an electronic computer) comprising a processing section using least squares for obtaining the corrected plateaux and energies. With a view to an automatic operation of radio-measurement chains, the programme also comprises a preliminary section in which the statistical considerations of B. Peirce have been applied in the version better known as Chauvenet's criterion; this has been done with a view to eliminate measurement results which are dubious and even totally wrong. (author) [French] Pour rendre possibles (au moins partiellement) des comparaisons objectives entre paliers de caracteristiques de compteurs a ionisation gazeuse, paliers traces lors de la mesure de chaque etalon radioactif de la production courante du L.M.R., il a ete ecrit un programme (sur machine a calculer electronique) comportant une partie de traitement par les moindres carres en vue de la determination de pentes et d'activites corrigees. En prevision d'une exploitation automatique de cha es de radio-mesure, le programme comporte en outre une partie preliminaire dans laquelle des considerations statistiques dues a B. Peirce ont ete appliquees dans leur version plus connue sous le nom de critere de Chauvenet et ce dans le but d'une elimination des resultats de mesure suspects et meme veritablement aberrants. (auteur)

  15. Origins of Programmable Nucleases for Genome Engineering.

    Science.gov (United States)

    Chandrasegaran, Srinivasan; Carroll, Dana

    2016-02-27

    Genome engineering with programmable nucleases depends on cellular responses to a targeted double-strand break (DSB). The first truly targetable reagents were the zinc finger nucleases (ZFNs) showing that arbitrary DNA sequences could be addressed for cleavage by protein engineering, ushering in the breakthrough in genome manipulation. ZFNs resulted from basic research on zinc finger proteins and the FokI restriction enzyme (which revealed a bipartite structure with a separable DNA-binding domain and a non-specific cleavage domain). Studies on the mechanism of cleavage by 3-finger ZFNs established that the preferred substrates were paired binding sites, which doubled the size of the target sequence recognition from 9 to 18bp, long enough to specify a unique genomic locus in plant and mammalian cells. Soon afterwards, a ZFN-induced DSB was shown to stimulate homologous recombination in cells. Transcription activator-like effector nucleases (TALENs) that are based on bacterial TALEs fused to the FokI cleavage domain expanded this capability. The fact that ZFNs and TALENs have been used for genome modification of more than 40 different organisms and cell types attests to the success of protein engineering. The most recent technology platform for delivering a targeted DSB to cellular genomes is that of the RNA-guided nucleases, which are based on the naturally occurring Type II prokaryotic CRISPR-Cas9 system. Unlike ZFNs and TALENs that use protein motifs for DNA sequence recognition, CRISPR-Cas9 depends on RNA-DNA recognition. The advantages of the CRISPR-Cas9 system-the ease of RNA design for new targets and the dependence on a single, constant Cas9 protein-have led to its wide adoption by research laboratories around the world. These technology platforms have equipped scientists with an unprecedented ability to modify cells and organisms almost at will, with wide-ranging implications across biology and medicine. However, these nucleases have also been shown to cut

  16. National Tuberculosis Control Programme.

    Science.gov (United States)

    Uke, B T

    1995-01-01

    Tuberculosis (TB) continues to be a major public health problem in India, since there are an estimated 2.5-3 million sputum positive cases and 5-6 million noninfectious cases in the country. The National Tuberculosis Program was established in 1962 with the main objective of reducing the disability and death from TB by effective treatment. Under the District Tuberculosis Program, district TB centers (DTCs) were set up for referral diagnosis, treatment, and community control of TB. Nationally, there are 390 districts with fully equipped DTCs staffed by a team of medical and paramedical personnel. Another 330 TB clinics are mostly located in big cities, caring for the local populace. In addition, 17 tuberculosis training and demonstration centers provide basic training to paramedical personnel, including general practitioners. There are a total of about 47,000 beds available nationwide for TB patients. The majority of patients are treated at home, thus only serious cases or those requiring surgical treatment are admitted. The NTP also stresses health education aimed at the community and general practitioners. Booklets, pamphlets, radio, TV, and newspaper advertisements are utilized for this purpose. International assistance has been provided by UNICEF, WHO, and the Swedish International Development Agency since the 1950s. The National Tuberculosis Institute was established in 1959 in Bangalore and it has engaged in research on epidemiological, sociological, and operations aspects, along with monitoring of the program. Other TB research institutes are the TB Research Center in Madras and the LRS Institute of TB and Allied Diseases in Delhi. BCG vaccination of children up to the age of 1 year continues, although a study showed that vaccination did not protect from adult TB. Evaluation of the NTP comprises quarterly reports for DTCs and countrywide assessment. NTP achievements include 85% coverage of districts, diagnosis of 1,500,000 new cases a year, and short

  17. Attendance in cancer screening programmes in Italy

    Directory of Open Access Journals (Sweden)

    Grazia Grazzini

    2008-06-01

    Full Text Available

    Background: The European Community recommends mammography, cervical and colorectal cancer screening programmes. In Italy, cancer screening programmes have been included in the Basic Healthcare Parameters (Livelli Essenziali di Assistenza since 2001. Full national coverage of a population-based organized screening programme has been planned for in Italy and is being implemented. Since 2005, the Ministry of Health - Department of Prevention has formally charged The National Centre for Screening Monitoring (Osservatorio Nazionale Screening –ONS- with monitoring and promoting screening programmes nationwide. Participation of target populations is a key indicator of the impact and efficacy of a screening programme in reducing cancer mortality.

    Methods: Attendance of invitees is one of the indicators calculated every year in the quality control of Italian screening programmes. Data collection is organized by means of a structured questionnaire, sent by ONS to the referent for data collection in each Region, who then returns the completed questionnaires to the Regional Centre. Questionnaires are then sent to the National Centre. Logical and epidemiologic checks are performed at both levels. Every year ONS publishes reports on the results of the surveys. A feasibility study for a National data warehouse based on individual records is in progress. The national survey “Multiscopo sulle famiglie” and the Passi Study (Progetti delle Aziende Sanitarie per la Salute in Italia provided additional information regarding spontaneous preventive health care activities in the Italian population.

    Results: Mammography screening: In 2006, 78.2% of Italian women aged 50-69 lived in areas where organised screening was in place (theoretical extension, however, the distribution of the screening activity is not uniform (higher in Northern/Central Italy compared with Southern

  18. Improving Latino Children's Early Language and Literacy Development: Key Features of Early Childhood Education within Family Literacy Programmes

    Science.gov (United States)

    Jung, Youngok; Zuniga, Stephen; Howes, Carollee; Jeon, Hyun-Joo; Parrish, Deborah; Quick, Heather; Manship, Karen; Hauser, Alison

    2016-01-01

    Noting the lack of research on how early childhood education (ECE) programmes within family literacy programmes influence Latino children's early language and literacy development, this study examined key features of ECE programmes, specifically teacher-child interactions and child engagement in language and literacy activities and how these…

  19. Report of the Director-General on the Long-Term Programme in the Field of Hydrology.

    Science.gov (United States)

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). General Conference.

    The report describes the principal orientations of the International Hydrological Programme, as well as the procedures suggested for its execution. The origin and justification of the programme are presented. The objectives of the 1975 programme are stated and the contents, which include the activities, themes, application of new techniques in…

  20. Improving Latino Children's Early Language and Literacy Development: Key Features of Early Childhood Education within Family Literacy Programmes

    Science.gov (United States)

    Jung, Youngok; Zuniga, Stephen; Howes, Carollee; Jeon, Hyun-Joo; Parrish, Deborah; Quick, Heather; Manship, Karen; Hauser, Alison

    2016-01-01

    Noting the lack of research on how early childhood education (ECE) programmes within family literacy programmes influence Latino children's early language and literacy development, this study examined key features of ECE programmes, specifically teacher-child interactions and child engagement in language and literacy activities and how these…