WorldWideScience

Sample records for activated manufacturing architecture

  1. Demand Activated Manufacturing Architecture (DAMA) model for supply chain collaboration

    Energy Technology Data Exchange (ETDEWEB)

    CHAPMAN,LEON D.; PETERSEN,MARJORIE B.

    2000-03-13

    The Demand Activated Manufacturing Architecture (DAMA) project during the last five years of work with the U.S. Integrated Textile Complex (retail, apparel, textile, and fiber sectors) has developed an inter-enterprise architecture and collaborative model for supply chains. This model will enable improved collaborative business across any supply chain. The DAMA Model for Supply Chain Collaboration is a high-level model for collaboration to achieve Demand Activated Manufacturing. The five major elements of the architecture to support collaboration are (1) activity or process, (2) information, (3) application, (4) data, and (5) infrastructure. These five elements are tied to the application of the DAMA architecture to three phases of collaboration - prepare, pilot, and scale. There are six collaborative activities that may be employed in this model: (1) Develop Business Planning Agreements, (2) Define Products, (3) Forecast and Plan Capacity Commitments, (4) Schedule Product and Product Delivery, (5) Expedite Production and Delivery Exceptions, and (6) Populate Supply Chain Utility. The Supply Chain Utility is a set of applications implemented to support collaborative product definition, forecast visibility, planning, scheduling, and execution. The DAMA architecture and model will be presented along with the process for implementing this DAMA model.

  2. Demand Activated Manufacturing Architecture (DAMA) supply chain collaboration development methodology

    Energy Technology Data Exchange (ETDEWEB)

    PETERSEN,MARJORIE B.; CHAPMAN,LEON D.

    2000-03-15

    The Demand Activated Manufacturing Architecture (DAMA) project during the last five years of work with the U.S. Integrated Textile Complex (retail, apparel, textile, and fiber sectors) has developed an inter-enterprise supply chain collaboration development methodology. The goal of this methodology is to enable a supply chain to work more efficiently and competitively. The outcomes of this methodology include: (1) A definitive description and evaluation of the role of business cultures and supporting business organizational structures in either inhibiting or fostering change to a more competitive supply chain; (2) ``As-Is'' and proposed ``To-Be'' supply chain business process models focusing on information flows and decision-making; and (3) Software tools that enable and support a transition to a more competitive supply chain, which results form a business driven rather than technologically driven approach to software design. This methodology development will continue in FY00 as DAMA engages companies in the soft goods industry in supply chain research and implementation of supply chain collaboration.

  3. APPLICATION OF IMPROVED PRODUCTION ACTIVITY CONTROL ARCHITECTURE FOR SHOP FLOOR INFORMATION SYSTEM IN DIGITAL MANUFACTURING

    Institute of Scientific and Technical Information of China (English)

    SHAHID Ikramullah Butt; SUN Houfang; GAO Zhengqing

    2006-01-01

    Shop floor control (SFC) is responsible for the coordination and control of the manufacturing physical and information flow within the shop floor in the manufacturing system. Weaknesses of the production activity control (PAC) architecture of the shop floor are addressed by the Maglica's new system architecture. This architecture gives rise to unlimited number of movers and producers thus evolving more complex but decentralized architecture. Beijing Institute of Technology - production activity control (BIT-PAC) architecture introduces an idea of sub-producers and sub-movers thus reducing the complexity of the architecture. All the equipments including sub-producers and sub-movers are considered to be passive in the proposed shop floor information system. The dissemination of information from sub-producers and sub-movers is done manually through a PC. Proposed BIT-PAC SFC architecture facilitates the information flow from shop floor to the other area of the organization. Effective use of internet information services (IIS) and SQL2000 is done along with the ASP. NET technology to implement the application logic. Applicability of the software based on BIT-PAC architecture is checked by running application software on a network PC that supports the dynamic flow of information from sub-producers and sub-movers to the other parts of the organization. Use of software is also shown at the end for BIT training workshop thus supporting the use of SFC architecture for similar kind of environments.

  4. A Grid Architecture for Manufacturing Database System

    Directory of Open Access Journals (Sweden)

    Laurentiu CIOVICĂ

    2011-06-01

    Full Text Available Before the Enterprise Resource Planning concepts business functions within enterprises were supported by small and isolated applications, most of them developed internally. Yet today ERP platforms are not by themselves the answer to all organizations needs especially in times of differentiated and diversified demands among end customers. ERP platforms were integrated with specialized systems for the management of clients, Customer Relationship Management and vendors, Supplier Relationship Management. They were integrated with Manufacturing Execution Systems for better planning and control of production lines. In order to offer real time, efficient answers to the management level, ERP systems were integrated with Business Intelligence systems. This paper analyses the advantages of grid computing at this level of integration, communication and interoperability between complex specialized informatics systems with a focus on the system architecture and data base systems.

  5. Design and Development of a CIM Architecture for Food Manufacturing

    Science.gov (United States)

    1994-07-01

    to support the IDEFIX Model Pro Software of D. Appleton, Inc., which requires a VGA monitor. This task, completed in the quarter ending April, 1990...architecture that covered both civilian and military product manufacture. This architecture, defined in IDEFIX modeling language, became the basis for...its extension, IDEFIX , is a methodology for modeling data entities and their relation- i ships. An entity is represented by a box labeled by a noun

  6. Architectural Design Activities for JAS

    CERN Document Server

    Khaled, Lena

    2009-01-01

    The critical part for building any software system is its architecture. Architectural design is a design at a higher level of abstraction. A good architecture ensures that software will satisfy its requirement. This paper defines the most important activities of architectural design that used through building any software; also it applies these activities on one type of Electronic Commerce (EC) applications that is Job Agency System(JAS) to show how these activities can work through these types of applications.

  7. An agile and cooperative architecture for distributed manufacturing systems

    OpenAIRE

    Leitão, Paulo; Restivo, Francisco

    2001-01-01

    World-wide competition among enterprises leads to the need for new systems to perform the control of distributed manufacturing systems, through the integration of information systems and self-organisation features, in order to adapt quickly to the environment changes. This paper presents an agile and cooperative architecture for distributed manufacturing systems based in the multiagent technology which implements some holonic and bionic concepts and supports a new control approach, including ...

  8. ARCHITECTURE OF MANUFACTURING EXECUTION SYSTEM IN THE EXTENDED ENTERPRISE

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The extended enterprise is formed according to the philosophy of dispersed networked manufacturing. Manufacturing execution system (MES) can close the information gap which exists between device control system and production information management system. The functions and the web-based architecture of the MES in the extended enterprise are introduced. Using the cooperating system models of object-oriented and distributed agents and CORBA, all objects keep to uniform interface standards and are easily inserted to object request broker. The utilization of distributed MES in extended enterprise can adapt fast change of manufacturing environment and resource. It also can improve the independent management capability of manufacturing cell and the enterprise response capability to global economic competition.

  9. ARCHITECTURE OF WEB BASED COMPUTER-AIDED MANUFACTURING SYSTEM

    Directory of Open Access Journals (Sweden)

    N. E. Filyukov

    2014-09-01

    Full Text Available The paper deals with design of a web-based system for Computer-Aided Manufacturing (CAM. Remote applications and databases located in the "private cloud" are proposed to be the basis of such system. The suggested approach contains: service - oriented architecture, using web applications and web services as modules, multi-agent technologies for implementation of information exchange functions between the components of the system and the usage of PDM - system for managing technology projects within the CAM. The proposed architecture involves CAM conversion into the corporate information system that will provide coordinated functioning of subsystems based on a common information space, as well as parallelize collective work on technology projects and be able to provide effective control of production planning. A system has been developed within this architecture which gives the possibility for a rather simple technological subsystems connect to the system and implementation of their interaction. The system makes it possible to produce CAM configuration for a particular company on the set of developed subsystems and databases specifying appropriate access rights for employees of the company. The proposed approach simplifies maintenance of software and information support for CAM subsystems due to their central location in the data center. The results can be used as a basis for CAM design and testing within the learning process for development and modernization of the system algorithms, and then can be tested in the extended enterprise.

  10. Final report: An enabling architecture for information driven manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Griesmeyer, J.M.

    1997-08-01

    This document is the final report for the LDRD: An Enabling Architecture for Information Driven Manufacturing. The project was motivated by the need to bring quality products to market quickly and to remain efficient and profitable with small lot sizes, intermittent production and short product life cycles. The emphasis is on integration of the product realization process and the information required to drive it. Enterprise level information was not addressed except in so far as the enterprise must provide appropriate information to the production equipment to specify what to produce, and the equipment must return enough information to record what was produced. A production script approach was developed in which the production script specifies all of the information required to produce a quality product. A task sequencer that decomposes the script into process steps which are dispatched to capable Standard Manufacturing Modules. The plug and play interface to these modules allows rapid introduction of new modules into the production system and speeds up the product realization cycle. The results of applying this approach to the Agile Manufacturing Prototyping System are described.

  11. An Improved Production Activity Control Architecture for Shop Floor Control

    Institute of Scientific and Technical Information of China (English)

    SHAHIDIkramullahButt; SUNHou-fang; HAMIDUllahKhanNiazi

    2005-01-01

    This paper presents a further improved Production Activity Control Architecture to deal with the complexity of information by creating Sub-Producers and Sub-Movers which will not only give a better control at workstation level but also reduce load on the Dispatcher. It also makes an analysis of the basic and improved PAC (Production Activity Control) Architecture in the Control System for Integrated Manufacturing. The PAC Architecture and the improvement will further enhance the flexibility and adaptability of the architecture in the ever changing environment of the Shop Floor Control (SFC) Systems.

  12. Architectural communication: Intra and extra activity of architecture

    Directory of Open Access Journals (Sweden)

    Stamatović-Vučković Slavica

    2013-01-01

    Full Text Available Apart from a brief overview of architectural communication viewed from the standpoint of theory of information and semiotics, this paper contains two forms of dualistically viewed architectural communication. The duality denotation/connotation (”primary” and ”secondary” architectural communication is one of semiotic postulates taken from Umberto Eco who viewed architectural communication as a semiotic phenomenon. In addition, architectural communication can be viewed as an intra and an extra activity of architecture where the overall activity of the edifice performed through its spatial manifestation may be understood as an act of communication. In that respect, the activity may be perceived as the ”behavior of architecture”, which corresponds to Lefebvre’s production of space.

  13. Hierarchical architecture of active knits

    Science.gov (United States)

    Abel, Julianna; Luntz, Jonathan; Brei, Diann

    2013-12-01

    Nature eloquently utilizes hierarchical structures to form the world around us. Applying the hierarchical architecture paradigm to smart materials can provide a basis for a new genre of actuators which produce complex actuation motions. One promising example of cellular architecture—active knits—provides complex three-dimensional distributed actuation motions with expanded operational performance through a hierarchically organized structure. The hierarchical structure arranges a single fiber of active material, such as shape memory alloys (SMAs), into a cellular network of interlacing adjacent loops according to a knitting grid. This paper defines a four-level hierarchical classification of knit structures: the basic knit loop, knit patterns, grid patterns, and restructured grids. Each level of the hierarchy provides increased architectural complexity, resulting in expanded kinematic actuation motions of active knits. The range of kinematic actuation motions are displayed through experimental examples of different SMA active knits. The results from this paper illustrate and classify the ways in which each level of the hierarchical knit architecture leverages the performance of the base smart material to generate unique actuation motions, providing necessary insight to best exploit this new actuation paradigm.

  14. An Architecture for Hybrid Manufacturing Combining 3D Printing and CNC Machining

    Directory of Open Access Journals (Sweden)

    Marcel Müller

    2016-01-01

    Full Text Available Additive manufacturing is one of the key technologies of the 21st century. Additive manufacturing processes are often combined with subtractive manufacturing processes to create hybrid manufacturing because it is useful for manufacturing complex parts, for example, 3D printed sensor systems. Currently, several CNC machines are required for hybrid manufacturing: one machine is required for additive manufacturing and one is required for subtractive manufacturing. Disadvantages of conventional hybrid manufacturing methods are presented. Hybrid manufacturing with one CNC machine offers many advantages. It enables manufacturing of parts with higher accuracy, less production time, and lower costs. Using the example of fused layer modeling (FLM, we present a general approach for the integration of additive manufacturing processes into a numerical control for machine tools. The resulting CNC architecture is presented and its functionality is demonstrated. Its application is beyond the scope of this paper.

  15. A Layered Software Architecture for the Management of a Manufacturing Company

    Directory of Open Access Journals (Sweden)

    Domenico CONSOLI

    2011-01-01

    Full Text Available In this paper we describe a layered software architecture in the management of a manufactur-ing company that intensively uses computer technology. Application tools, new and legacy, after the updating, operate in a context of an open web oriented architecture. The software architecture enables the integration and interoperability among all tools that support business processes. Manufacturing Executive System and Text Mining tools are excellent interfaces, the former both for internal production and management processes and the latter for external processes coming from the market. In this way, it is possible to implement, a computer integrated factory, flexible and agile, that immediately responds to customer requirements.

  16. Adaptive compensation of sculptured surface machining errors by open architecture manufacturing system

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Presents the adaptive compensation of sculptured surfacemachining errors by using the open architecture intelligent manufacturing system to ensure real-time high-precision machining of sculptured surface, and the tool deflection model constructed for prediction of machining errors to be compensated and analysis of the effect of tool deflection on machining errors, and concludes from experimental results that the open architecture intelligent manufacturing system can effectively improve the machining precision and reduce the machining errors by 30%.

  17. Design of a modular product architecture and a cellular manufacturing layout : A concurrent engineering approach

    NARCIS (Netherlands)

    Slomp, J; McGinnis, LF; Ahmad, MM; Sullivan, WG

    1996-01-01

    This paper formalizes the problem of a concurrent design of a modular product architecture and a cellular manufacturing layout and presents a way to deal with this design problem. First, the different types of a modular product architecture are explained as well as important implications of modulari

  18. Reconfigurable Equiplets Operating System A Hybrid Architecture to Combine Flexibility and Performance for Manufacturing

    NARCIS (Netherlands)

    Telgen, Daniël; Puik, Erik; Moergestel, leo van; Bakker, Tommas; Meyer, John-Jules

    2015-01-01

    Author supplied: Abstract—The growing importance and impact of new technologies are changing many industries. This effect is especially noticeable in the manufacturing industry. This paper explores a practical implementation of a hybrid architecture for the newest generation of manufacturing systems

  19. Solar collector manufacturing activity, 1992

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-09

    This report presents data provided by US-based manufacturers and importers of solar collectors. Summary data on solar thermal collector shipments are presented for the years 1974 through 1992. Summary data on photovoltaic cell and module shipments are presented for the years 1982 through 1992. Detailed information for solar thermal collectors and photovoltaic cells and modules are presented for 1992. Appendix A describes the survey methodology. Appendix B contains the 1992 survey forms and instructions. Appendices C and D list the companies that responded to the 1992 surveys and granted permission for their names and addresses to appear in the report. Appendix E provides selected tables from this report with data shown in the International System of Units (SI) metric units. Appendix F provides an estimate of installed capacity and energy production from solar collectors for 1992.

  20. Global Sourcing of Services Versus Manufacturing Activities

    DEFF Research Database (Denmark)

    Ørberg Jensen, Peter D.; Petersen, Bent

    2012-01-01

    International sourcing strategies and operations are usually described distinctively for manufacturing and services. In this paper, the theoretical and strategic relevance of this distinction is questioned. As an alternative, an activity-based theoretical framework for exploring the linkages betw...... strategy, activity and organization is a key determinant of the success of the sourcing process and outcome....

  1. 15 CFR 400.31 - Manufacturing and processing activity; criteria.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Manufacturing and processing activity... ZONES BOARD Manufacturing and Processing Activity-Reviews § 400.31 Manufacturing and processing activity....” When evaluating zone and subzone manufacturing and processing activity, either as proposed in...

  2. The Management of Manufacturing-Oriented Informatics Systems Using Efficient and Flexible Architectures

    Directory of Open Access Journals (Sweden)

    Constantin Daniel AVRAM

    2011-01-01

    Full Text Available Industry and in particular the manufacturing-oriented sector has always been researched and innovated as a result of technological progress, diversification and differentiation among consumers' demands. A company that provides to its customers products matching perfectly their demands at competitive prices has a great advantage over its competitors. Manufacturing-oriented information systems are becoming more flexible and configurable and they require integration with the entire organization. This can be done using efficient software architectures that will allow the coexistence between commercial solutions and open source components while sharing computing resources organized in grid infrastructures and under the governance of powerful management tools.

  3. Laminated Panel Manufacture of Two Kinds of Bamboo for Architecture Material and Property Comparison

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    The manufacture technologies of two kinds of bamboo laminated panel and their physical-mechanical properties have been studied in the paper. The species of bamboo are the D. yunnanicus Hsueh et D. Z. Li in Yunnan Province and P. heterocycla var. pubescens Ohwi in Zhejiang Province. The data are offered in order to provide proof to produce architectural panel by bamboo materials. The results show as follows: Laminated bamboo panel can be produced by the reconstruction technology, and the mechanical prope...

  4. Outsourcing of Logistics Activities in Manufacturing Industry

    Directory of Open Access Journals (Sweden)

    Anton Ogorelc

    2012-10-01

    Full Text Available The external supply of logistics se1vices is part of a trend towardoutsourcing non-core logistics activities. The scope ofthird-party logistics may range from a relatively limited combinationof activities (e.g. transportation and warehousing to acomprehensive set of logistics se1vices.The authors first discuss the characteristics of business logisticsin manufacturing indusfly, to be taken into account inlogistics outsourcing. They particularly point out the motimtionsfor logistics outsourcing, the possibilities of outsourcing,as well as supplier selection. Finally they analyze the outsourcingin the reverse logistics.

  5. ARCHITECTURE IN RECONFIGURABLE MANUFACTURING SYSTEM*%可重构制造系统的体系结构

    Institute of Scientific and Technical Information of China (English)

    郭志平

    2001-01-01

    可重构制造系统是现代企业生存和发展的基本手段,具有较高可重构性的企业能在难以预测的环境中,面对竞争对手脱颖而出.本文从可重构制造系统的概念,组织体系,商业体系,产品体系及信息体系等方面研究了可重构制造系统的体系结构,探讨了可重构制造系统的可行性.%Reconfigurable manufacturing system is an essential means for a modern enterprise to survive and. develop. The enterprise of having reconfigurable manufacturing ability can go beyond from other enterprise and be well always at a constantly changing and unforeseeing environment. This paper discusses architecture in reconfigurable manufacturing system from the six aspects of the concept of reconfigurable manufacturing system, reconfigurable organization architecture, reconfigurable business architecture, reconfigurable product architecture and reconfigurable workshop machine architecture and reconfigurable information architecture. Their relations one anther and contexts show the architecture frame of a manufacture system in this paper.

  6. An Open CNC Based Integrated Measuring, Modeling and Manufacturing System Architecture

    Institute of Scientific and Technical Information of China (English)

    WANG Huabing; LIU Weijun

    2006-01-01

    A new architecture based on open-architecture CNC of an integrated measuring, modeling and manufacturing system is presented. A 3-axis vertical milling structure is used to achieve the manufacturing function. And a computer vision camera is to be set up on the holder of the milling machine to capture the images of the work-piece and a image data acquisition card is used to translate the image data to the control computer, which acts as the measuring subsystem. Through processing the image data the model of the work-piece is established which plays the role of modeling subsystem. A motion control card is inserted into an industry computer to construct an open CNC system of the type of NC embedded PC which is more sophisticated than other new technologies on open CNC. The embedded motion card burdens the real-time tasks of the system and the IPC does the other management and planning tasks. The IPC together with the motion control card command the three axes of the system to accomplish the manufacturing and measuring functions and further the modeling function.

  7. Proposal of a Methodology for Implementing a Service-Oriented Architecture in Distributed Manufacturing Systems

    Science.gov (United States)

    Medina, I.; Garcia-Dominguez, A.; Aguayo, F.; Sevilla, L.; Marcos, M.

    2009-11-01

    As envisioned by Intelligent Manufacturing Systems (IMS), Next Generation Manufacturing Systems (NGMS) will satisfy the needs of an increasingly fast-paced and demanding market by dynamically integrating systems from inside and outside the manufacturing firm itself into a so-called extended enterprise. However, organizing these systems to ensure the maximum flexibility and interoperability with those from other organizations is difficult. Additionally, a defect in the system would have a great impact: it would affect not only its owner, but also its partners. For these reasons, we argue that a service-oriented architecture (SOA) would be a good candidate. It should be designed following a methodology where services play a central role, instead of being an implementation detail. In order for the architecture to be reliable enough as a whole, the methodology will need to help find errors before they arise in a production environment. In this paper we propose using SOA-specific testing techniques, compare some of the existing methodologies and outline several extensions upon one of them to integrate testing techniques.

  8. 15 CFR Supplement No. 2 to Part 783 - Manufacturing Activities

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Manufacturing Activities No. Supplement No. 2 to Part 783 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... Part 783—Manufacturing Activities The following constitute manufacturing activities that require...

  9. Evaluation of the Impact of an Additive Manufacturing Enhanced CubeSat Architecture on the CubeSat Development Process

    Science.gov (United States)

    2016-09-15

    structures, including the propulsion system, at less cost than current CubeSat manufacturing methods (Moore et al., 2010). Because CubeSats are often a...development and manufacturing, where each build is unique. Due to the issues of long development schedules and high development and manufacturing costs ...architecture is a quantitative demonstration of how AM techniques can decrease mass, decrease volume, increase delta V (a measure of the impulse

  10. 27 CFR 40.526 - Minimum manufacturing and activity requirements.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Minimum manufacturing and activity requirements. 40.526 Section 40.526 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX... Manufacturers of Processed Tobacco § 40.526 Minimum manufacturing and activity requirements. A permit...

  11. 27 CFR 40.256 - Minimum manufacturing and activity requirements.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Minimum manufacturing and... Provisions Relating to Operations § 40.256 Minimum manufacturing and activity requirements. The minimum manufacturing and activity requirement prescribed in § 40.61(b) of this part is a continuing condition of...

  12. Virtual Manufacturing Techniques Designed and Applied to Manufacturing Activities in the Manufacturing Integration and Technology Branch

    Science.gov (United States)

    Shearrow, Charles A.

    1999-01-01

    One of the identified goals of EM3 is to implement virtual manufacturing by the time the year 2000 has ended. To realize this goal of a true virtual manufacturing enterprise the initial development of a machinability database and the infrastructure must be completed. This will consist of the containment of the existing EM-NET problems and developing machine, tooling, and common materials databases. To integrate the virtual manufacturing enterprise with normal day to day operations the development of a parallel virtual manufacturing machinability database, virtual manufacturing database, virtual manufacturing paradigm, implementation/integration procedure, and testable verification models must be constructed. Common and virtual machinability databases will include the four distinct areas of machine tools, available tooling, common machine tool loads, and a materials database. The machine tools database will include the machine envelope, special machine attachments, tooling capacity, location within NASA-JSC or with a contractor, and availability/scheduling. The tooling database will include available standard tooling, custom in-house tooling, tool properties, and availability. The common materials database will include materials thickness ranges, strengths, types, and their availability. The virtual manufacturing databases will consist of virtual machines and virtual tooling directly related to the common and machinability databases. The items to be completed are the design and construction of the machinability databases, virtual manufacturing paradigm for NASA-JSC, implementation timeline, VNC model of one bridge mill and troubleshoot existing software and hardware problems with EN4NET. The final step of this virtual manufacturing project will be to integrate other production sites into the databases bringing JSC's EM3 into a position of becoming a clearing house for NASA's digital manufacturing needs creating a true virtual manufacturing enterprise.

  13. Physical Activity Design Guidelines for School Architecture.

    Directory of Open Access Journals (Sweden)

    Jeri Brittin

    Full Text Available Increasing children's physical activity at school is a national focus in the U.S. to address childhood obesity. While research has demonstrated associations between aspects of school environments and students' physical activity, the literature currently lacks a synthesis of evidence to serve as a practical, spatially-organized resource for school designers and decision-makers, as well as to point to pertinent research opportunities. This paper describes the development of a new practical tool: Physical Activity Design Guidelines for School Architecture. Its aims are to provide architects and designers, as well as school planners, educators, and public health professionals, with strategies for making K-12 school environments conducive to healthy physical activity, and to engage scientists in transdisciplinary perspectives toward improved knowledge of the school environment's impact. We used a qualitative review process to develop evidence-based and theory-driven school design guidelines that promote increased physical activity among students. The design guidelines include specific strategies in 10 school design domains. Implementation of the guidelines is expected to enable students to adopt healthier physical activity behaviors. The tool bridges a translational gap between research and environmental design practice, and may contribute to setting new industry and education standards.

  14. Physical Activity Design Guidelines for School Architecture.

    Science.gov (United States)

    Brittin, Jeri; Sorensen, Dina; Trowbridge, Matthew; Lee, Karen K; Breithecker, Dieter; Frerichs, Leah; Huang, Terry

    2015-01-01

    Increasing children's physical activity at school is a national focus in the U.S. to address childhood obesity. While research has demonstrated associations between aspects of school environments and students' physical activity, the literature currently lacks a synthesis of evidence to serve as a practical, spatially-organized resource for school designers and decision-makers, as well as to point to pertinent research opportunities. This paper describes the development of a new practical tool: Physical Activity Design Guidelines for School Architecture. Its aims are to provide architects and designers, as well as school planners, educators, and public health professionals, with strategies for making K-12 school environments conducive to healthy physical activity, and to engage scientists in transdisciplinary perspectives toward improved knowledge of the school environment's impact. We used a qualitative review process to develop evidence-based and theory-driven school design guidelines that promote increased physical activity among students. The design guidelines include specific strategies in 10 school design domains. Implementation of the guidelines is expected to enable students to adopt healthier physical activity behaviors. The tool bridges a translational gap between research and environmental design practice, and may contribute to setting new industry and education standards.

  15. An Architecture for Hybrid Manufacturing Combining 3D Printing and CNC Machining

    OpenAIRE

    Marcel Müller; Elmar Wings

    2016-01-01

    Additive manufacturing is one of the key technologies of the 21st century. Additive manufacturing processes are often combined with subtractive manufacturing processes to create hybrid manufacturing because it is useful for manufacturing complex parts, for example, 3D printed sensor systems. Currently, several CNC machines are required for hybrid manufacturing: one machine is required for additive manufacturing and one is required for subtractive manufacturing. Disadvantages of conventional h...

  16. LSST active optics system software architecture

    Science.gov (United States)

    Thomas, Sandrine J.; Chandrasekharan, Srinivasan; Lotz, Paul; Xin, Bo; Claver, Charles; Angeli, George; Sebag, Jacques; Dubois-Felsmann, Gregory P.

    2016-08-01

    The Large Synoptic Survey Telescope (LSST) is an 8-meter class wide-field telescope now under construction on Cerro Pachon, near La Serena, Chile. This ground-based telescope is designed to conduct a decade-long time domain survey of the optical sky. In order to achieve the LSST scientific goals, the telescope requires delivering seeing limited image quality over the 3.5 degree field-of-view. Like many telescopes, LSST will use an Active Optics System (AOS) to correct in near real-time the system aberrations primarily introduced by gravity and temperature gradients. The LSST AOS uses a combination of 4 curvature wavefront sensors (CWS) located on the outside of the LSST field-of-view. The information coming from the 4 CWS is combined to calculate the appropriate corrections to be sent to the 3 different mirrors composing LSST. The AOS software incorporates a wavefront sensor estimation pipeline (WEP) and an active optics control system (AOCS). The WEP estimates the wavefront residual error from the CWS images. The AOCS determines the correction to be sent to the different degrees of freedom every 30 seconds. In this paper, we describe the design and implementation of the AOS. More particularly, we will focus on the software architecture as well as the AOS interactions with the various subsystems within LSST.

  17. An agent-based peer-to-peer architecture for semantic discovery of manufacturing services across virtual enterprises

    Science.gov (United States)

    Zhang, Wenyu; Zhang, Shuai; Cai, Ming; Jian, Wu

    2015-04-01

    With the development of virtual enterprise (VE) paradigm, the usage of serviceoriented architecture (SOA) is increasingly being considered for facilitating the integration and utilisation of distributed manufacturing resources. However, due to the heterogeneous nature among VEs, the dynamic nature of a VE and the autonomous nature of each VE member, the lack of both sophisticated coordination mechanism in the popular centralised infrastructure and semantic expressivity in the existing SOA standards make the current centralised, syntactic service discovery method undesirable. This motivates the proposed agent-based peer-to-peer (P2P) architecture for semantic discovery of manufacturing services across VEs. Multi-agent technology provides autonomous and flexible problemsolving capabilities in dynamic and adaptive VE environments. Peer-to-peer overlay provides highly scalable coupling across decentralised VEs, each of which exhibiting as a peer composed of multiple agents dealing with manufacturing services. The proposed architecture utilises a novel, efficient, two-stage search strategy - semantic peer discovery and semantic service discovery - to handle the complex searches of manufacturing services across VEs through fast peer filtering. The operation and experimental evaluation of the prototype system are presented to validate the implementation of the proposed approach.

  18. Real-time collaboration in activity-based architectures

    DEFF Research Database (Denmark)

    Bardram, Jakob Eyvind; Christensen, Henrik Bærbak

    2004-01-01

    With the growing research into mobile and ubiquitous computing, there is a need for addressing how such infrastructures can support collaboration between nomadic users. We present the activity based computing paradigm and outline a proposal for handling collaboration in an activity......-based architecture. We argue that activity-based computing establishes a natural and sound conceptual and architectural basis for session management in real-time, synchronous collaboration....

  19. Operations Assessment of Launch Vehicle Architectures using Activity Based Cost Models

    Science.gov (United States)

    Ruiz-Torres, Alex J.; McCleskey, Carey

    2000-01-01

    The growing emphasis on affordability for space transportation systems requires the assessment of new space vehicles for all life cycle activities, from design and development, through manufacturing and operations. This paper addresses the operational assessment of launch vehicles, focusing on modeling the ground support requirements of a vehicle architecture, and estimating the resulting costs and flight rate. This paper proposes the use of Activity Based Costing (ABC) modeling for this assessment. The model uses expert knowledge to determine the activities, the activity times and the activity costs based on vehicle design characteristics. The approach provides several advantages to current approaches to vehicle architecture assessment including easier validation and allowing vehicle designers to understand the cost and cycle time drivers.

  20. CAAD as Computer-Activated Architectural Design

    DEFF Research Database (Denmark)

    Galle, Per

    1998-01-01

    In a brief sketch, drawing on a general philosophical conception of human interaction with the world, the architectural design process is analysed in terms of two kinds of human action: interpretation and production. Both of these are seen as establishing a link between mental and material entiti...

  1. Constructing Active Architectures in the ArchWare ADL

    CERN Document Server

    Morrison, Ron; Balasubramaniam, Dharini; Mickan, Kath; Oquendo, Flavio; Cîmpan, Sorana; Warboys, Brian; Snowdon, Bob; Greenwood, Mark

    2010-01-01

    Software that cannot change is condemned to atrophy: it cannot accommodate the constant revision and re-negotiation of its business goals nor intercept the potential of new technology. To accommodate change in such systems we have defined an active software architecture to be: dynamic in that the structure and cardinality of the components and interactions are not statically known; updatable in that components can be replaced dynamically; and evolvable in that it permits its executing specification to be changed. Here we describe the facilities of the ArchWare architecture description language (ADL) for specifying active architectures. The contribution of the work is the unique combination of concepts including: a {\\pi}-calculus based communication and expression language for specifying executable architectures; hyper-code as an underlying representation of system execution; a decomposition operator to break up and introspect on executing systems; and structural reflection for creating new components and bind...

  2. A Novel Active Network Architecture Based on Extensible Services Router

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Active networks are a new kind of packet-switched networks in which packets have code fragments that are executed on the intermediary nodes (routers). The code can extend or modify the foundation architecture of a network. In this paper, the authors present a novel active network architecture combined with advantages of two major active networks technology based on extensible services router. The architecture consists of extensible service router, active extensible components server and key distribution center (KDC). Users can write extensible service components with programming interface. At the present time, we have finished the extensible services router prototype system based on Highly Efficient Router Operating System (HEROS), active extensible components server and KDC prototype system based on Linux.

  3. Cloud-based multi-agent architecture for effective planning and scheduling of distributed manufacturing

    DEFF Research Database (Denmark)

    Mishra, Nishikant; Singh, Akshit; Kumari, Sushma

    2016-01-01

    In modern world, manufacturing processes have become very complex because of consistently fluctuating demand of customers. Numerous production facilities located at various geographical locations are being utilised to address the demands of their multiple clients. Often, the components manufactured...... at distinct locations are being assembled in a plant to develop the final product. In this complex scenario, manufacturing firms have to be responsive enough to cope with the fluctuating demand of customers. To accomplish it, there is a need to develop an integrated, dynamic and autonomous system...... described in this study demonstrates how the autonomous agents interact with each other to rectify the internal discrepancies in manufacturing system. It can also address the external interferences like variations in client’s orders to maximise the profit of manufacturing firm in both short and long term...

  4. Computational Strategies for the Architectural Design of Bending Active Structures

    DEFF Research Database (Denmark)

    Tamke, Martin; Nicholas, Paul

    2013-01-01

    with the design of bending-active structures, through computational strategies. We report three built structures that develop architecturally oriented design methods for bending-active systems using composite materials. These projects demonstrate the application and limits of the introduction of advanced...

  5. Solar-collector manufacturing activity, July through December, 1981

    Energy Technology Data Exchange (ETDEWEB)

    None

    1982-03-01

    Solar thermal collector and solar cell manufacturing activity is both summarized and tabulated. Data are compared for three survey periods (July through December, 1981; January through June, 1981; and July through December, 1980). Annual totals are also provided for the years 1979 through 1981. Data include total producer shipments, end use, market sector, imports and exports. (LEW)

  6. Maya Lime Mortars—Relationship between Archaeomagnetic Dating, Manufacturing Technique, and Architectural Function—The Dzibanché Case

    Directory of Open Access Journals (Sweden)

    Luisa Straulino Mainou

    2016-11-01

    Full Text Available Researchers have related the manufacturing technique of plasters and stucco in the Maya area with their period of production but not with their architectural function. In this paper, we establish a relationship between those three features (manufacturing technique, age, and architectural function in the plasters of the Maya site of Dzibanché in southern Quintana Roo. Dzibanché has abundant remains of stuccos and plasters found mainly in three buildings (Plaza Pom, Pequeña Acrópolis, and Structure 2. We used thin sections, SEM and XRD, and archaeomagnetic dating processes. The pictorial layer of Structure 2 was the earliest (AD 274–316 and the stuccoes and plasters of the other two buildings were dated to the Middle Classic (AD 422–531, but we obtained different archaeomagnetic dates for the red pigment layers found in the buildings of the Pequeña Acrópolis and thus we were able to determine their chronological order of construction. The raw materials and proportions were carefully chosen to fulfil the mechanical necessities of the architectonic function: different proportions were found in plasters of floors, in the external walls, and inside the buildings; differences between earlier and later plasters were also detected.

  7. RETROFITTING AN AUTOMATIC MANUFACTURING WORKCELL FOR STUDY OF OPEN ARCHITECTURE INTEGRATION OF MECHATRONIC SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Research work on plug-and-play open architecture and object-oriented mechatronic system integration is described. The original controllers of two popular industrial robot manipulators Puma 560 and IBM 7575 are completely retrofitted and integrated with a conveyor system to form a robot workcell. This robot workcell can be programmed to run under the Ch language environment. The outline of the Ch language, and the retrofitting strategy of the robot workcell will be described. A sample application program for simulated assembly operations of this robot workcell will be presented to demonstrate the underlying principles of open architecture integration of mechatronic systems under the programming paradigm of the Ch language environment.

  8. Multiscale architectured materials with composition and grain size gradients manufactured using high-pressure torsion.

    Science.gov (United States)

    Kang, Ji Yun; Kim, Jung Gi; Park, Hyo Wook; Kim, Hyoung Seop

    2016-05-27

    The concept of multiscale architectured materials is established using composition and grain size gradients. Composition-gradient nanostructured materials are produced from coarse grained interstitial free steels via carburization and high-pressure torsion. Quantitative analyses of the dislocation density using X-ray diffraction and microstructural studies clearly demonstrate the gradients of the dislocation density and grain size. The mechanical properties of the gradient materials are compared with homogeneous nanostructured carbon steel without a composition gradient in an effort to investigate the gradient effect. Based on the above observations, the potential of multiscale architecturing to open a new material property is discussed.

  9. 15 CFR 400.33 - Restrictions on manufacturing and processing activity.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Restrictions on manufacturing and...-TRADE ZONES BOARD Manufacturing and Processing Activity-Reviews § 400.33 Restrictions on manufacturing and processing activity. (a) In general. In approving manufacturing or processing activity for a...

  10. Methods and Software Architecture for Activity Recognition from Position Data

    DEFF Research Database (Denmark)

    Godsk, Torben

    rates -- both in an offline setup as well as in real-time with continuously streamed data. In real-time, I am able to classify the five activities with success rates of: 97.8%, 85.2%, 84%, 93.7% and 72.2%, respectively, with a weighted average of 90.6%. Moreover, when doing the classification offline, I......This thesis describes my studies on the subject of recognizing cow activities from satellite based position data. The studies comprise methods and software architecture for activity recognition from position data, applied to cow activity recognition. The development of methods and software...... architecture is the first step towards a decision support system for dairy farmers. The system is to include a component for recognition of cow activities. The decision support system will -- in its final version -- convert the result of the activity recognition to knowledge about the cows' individual behavior...

  11. Evaluating a Prototype Approach to Validating a DDS-based System Architecture for Automated Manufacturing Environments

    NARCIS (Netherlands)

    Essers, M.S.; Vaneker, T.H.J.

    2014-01-01

    Data Distribution Services (DDS) are emerging as communication systems in manufacturing environments. One of the key features of a DDS based system is the ability to regain performance levels after the introduction or removal of a DDS participant. In implementing a DDS participant to an existing sys

  12. Scheduling Activity in an Agent Architecture

    OpenAIRE

    Soto, Ignacio

    2000-01-01

    Agents for applications in dynamic environments require artificial intelligence techniques to solve problems to achieve their objectives. For example, they must develop plans of actions to carry out missions in their environment, in other words, to achieve some state in the world. But also, the agents must fulfill real-time requirements that arise because the characteristics of the applications and the dynamism of the environment. In this paper we analyze the use of a schedule of activity in ...

  13. In Situ Manufacturing is a Necessary Part of Any Planetary Architecture

    Science.gov (United States)

    Edmunson, Jennifer E.; McLemore, Carole A.

    2012-01-01

    The key to any sustainable presence in space is the ability to manufacture necessary tools, parts, structures, spares, etc. in situ and on demand. Cost, volume, and up-mass constraints prohibit launching everything needed for long-duration or long-distance missions from Earth, including spare parts and replacement systems. There are many benefits to building items as-needed in situ using computer aided drafting (CAD) models and additive manufacturing technology: (1) Cost, up-mass, and volume savings for launch due to the ability to manufacture specific parts when needed. (2) CAD models can be generated on Earth and transmitted to the station or spacecraft, or they can be designed in situ for any task. Thus, multiple people in many locations can work on a single problem. (3) Items can be produced that will enhance the safety of crew and vehicles (e.g., latches or guards). (4) Items can be produced on-demand in a small amount of time (i.e., hours or days) compared to traditional manufacturing methods and, therefore, would not require the lengthy amount of time needed to machine the part from a solid block of material nor the wait time required if the part had to be launched from Earth. (5) Used and obsolete parts can be recycled into powder or wire feedstock for use in later manufacturing. (6) Ultimately, the ability to produce items as-needed will reduce mission risk, as one will have everything they need to fix a broken system or fashion a new part making it available on a more timely basis.

  14. Performance and modeling of active metal-matrix composites manufactured by ultrasonic additive manufacturing

    Science.gov (United States)

    Hahnlen, Ryan; Dapino, Marcelo J.

    2011-04-01

    This paper presents the development and characterization of active aluminum-matrix composites manufactured by Ultrasonic Additive Manufacturing (UAM), an emerging rapid prototyping process based on ultrasonic metal welding. The primary benefit of UAM over other metal-matrix fabrication processes is the low process temperatures, as low as 25 °C. UAM thus provides unprecedented opportunities to develop adaptive structures with seamlessly embedded smart materials and electronic components without degrading the properties that make these materials and components attractive. The objective of this research is to develop UAM composites with aluminum matrices and embedded shape memory NiTi, magnetostrictive Galfenol (FeGa), and polyvinylidene fluoride (PVDF) phases. The paper is focused on the thermally induced strain response and stiffness behavior of NiTi-Al composites, the actuation properties of FeGa-Al composites, and the embedded sensing capabilities of PVDF-Al composites. We observe up to a 10% increase over room temperature stiffness for NiTi-Al composites and a magnetomechanical response in the FeGa-Al composite up to 52.4 μɛ. The response of the PVDF-Al composite to harmonic loads is observed over a frequency range of 10 to 1000 Hz.

  15. Additive manufacturing and mechanical characterization of graded porosity scaffolds designed based on triply periodic minimal surface architectures.

    Science.gov (United States)

    Afshar, M; Anaraki, A Pourkamali; Montazerian, H; Kadkhodapour, J

    2016-09-01

    Since the advent of additive manufacturing techniques, triply periodic minimal surfaces have emerged as a novel tool for designing porous scaffolds. Whereas scaffolds are expected to provide multifunctional performance, spatially changing pore patterns have been a promising approach to integrate mechanical characteristics of different architectures into a unique scaffold. Smooth morphological variations are also frequently seen in nature particularly in bone and cartilage structures and can be inspiring for designing of artificial tissues. In this study, we carried out experimental and numerical procedures to uncover the mechanical properties and deformation mechanisms of linearly graded porosity scaffolds for two different mathematically defined pore structures. Among TPMS-based scaffolds, P and D surfaces were subjected to gradient modeling to explore the mechanical responses for stretching and bending dominated deformations, respectively. Moreover, the results were compared to their corresponding uniform porosity structures. Mechanical properties were found to be by far greater for the stretching dominated structure (P-Surface). For bending dominated architecture (D-Surface), although there was no global fracture for uniform structures, graded structure showed a brittle fracture at 0.08 strain. A layer by layer deformation mechanism for stretching dominated structure was observed. For bending dominated scaffolds, deformation was accompanied by development of 45° shearing bands. Finite element simulations were also performed and the results showed a good agreement with the experimental observations.

  16. Mesoscale architecture shapes initiation and richness of spontaneous network activity.

    Science.gov (United States)

    Okujeni, Samora; Kandler, Steffen; Egert, Ulrich

    2017-03-14

    Spontaneous activity in the absence of external input, including propagating waves of activity, is a robust feature of neuronal networks in vivo and in vitro. The neurophysiological and anatomical requirements for initiation and persistence of such activity, however, are poorly understood, as is their role in the function of neuronal networks. Computational network studies indicate that clustered connectivity may foster the generation, maintenance and richness of spontaneous activity. Since this mesoscale architecture cannot be systematically modified in intact tissue, testing these predictions is impracticable in vivo. Here, we investigate how the mesoscale structure shapes spontaneous activity in generic networks of rat cortical neurons in vitro. In these networks, neurons spontaneously arrange into local clusters with high neurite density and form fasciculating long-range axons. We modified this structure by modulation of protein kinase C, an enzyme regulating neurite growth and cell migration. Inhibition of protein kinase C reduced neuronal aggregation and fasciculation of axons, i.e. promoted uniform architecture. Conversely, activation of protein kinase C promoted aggregation of neurons into clusters, local connectivity and bundling of long-range axons. Supporting predictions from theory, clustered networks were more spontaneously active and generated diverse activity patterns. Neurons within clusters received stronger synaptic inputs and displayed increased membrane potential fluctuations. Intensified clustering promoted the initiation of synchronous bursting events but entailed incomplete network recruitment. Moderately clustered networks appear optimal for initiation and propagation of diverse patterns of activity. Our findings support a crucial role of the mesoscale architectures in the regulation of spontaneous activity dynamics.SIGNIFICANCE STATEMENTComputational studies predict richer and persisting spatio-temporal patterns of spontaneous activity in

  17. A High-Speed Active Switch Routing Architecture

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    In this paper, combining with active networks, we design a new kind of programmable routing switch architecture to provide a common intelligent switch platform for multi-protocol switching and multi-service accessing. We elaborate how programmable switch and network intelligence are achieved, and how packets are classified, queued and scheduled. We point out that edge intelligence and network software are the tendency for the development of future networks.

  18. Lifecycle Prognostics Architecture for Selected High-Cost Active Components

    Energy Technology Data Exchange (ETDEWEB)

    N. Lybeck; B. Pham; M. Tawfik; J. B. Coble; R. M. Meyer; P. Ramuhalli; L. J. Bond

    2011-08-01

    There are an extensive body of knowledge and some commercial products available for calculating prognostics, remaining useful life, and damage index parameters. The application of these technologies within the nuclear power community is still in its infancy. Online monitoring and condition-based maintenance is seeing increasing acceptance and deployment, and these activities provide the technological bases for expanding to add predictive/prognostics capabilities. In looking to deploy prognostics there are three key aspects of systems that are presented and discussed: (1) component/system/structure selection, (2) prognostic algorithms, and (3) prognostics architectures. Criteria are presented for component selection: feasibility, failure probability, consequences of failure, and benefits of the prognostics and health management (PHM) system. The basis and methods commonly used for prognostics algorithms are reviewed and summarized. Criteria for evaluating PHM architectures are presented: open, modular architecture; platform independence; graphical user interface for system development and/or results viewing; web enabled tools; scalability; and standards compatibility. Thirteen software products were identified and discussed in the context of being potentially useful for deployment in a PHM program applied to systems in a nuclear power plant (NPP). These products were evaluated by using information available from company websites, product brochures, fact sheets, scholarly publications, and direct communication with vendors. The thirteen products were classified into four groups of software: (1) research tools, (2) PHM system development tools, (3) deployable architectures, and (4) peripheral tools. Eight software tools fell into the deployable architectures category. Of those eight, only two employ all six modules of a full PHM system. Five systems did not offer prognostic estimates, and one system employed the full health monitoring suite but lacked operations and

  19. A Single-Transistor Active Pixel CMOS Image Sensor Architecture

    Institute of Scientific and Technical Information of China (English)

    ZHANG Guo-An; ZHANG Dong-Wei; HE Jin; SU Yan-Mei; WANG Cheng; CHEN Qin; LIANG Hai-Lang; YE Yun

    2012-01-01

    A single-transistor CMOS active pixel image sensor (1T CMOS APS) architecture is proposed,By switching the photosensing pinned diode,resetting and selecting can be achieved by diode pull-up and capacitive coupling pull-down of the source follower. Thus,the reset and selected transistors can be removed. In addition,the reset and selected signal lines can be shared to reduce the metal signal line,leading to a very high fill factor.The pixel design and operation principles are discussed in detail.The functionality of the proposed 1 T CMOS APS architecture has been experimentally verified using a fabricated chip in a standard 0.35 μm CMOS AMIS technology.

  20. Influence of Additive Manufactured Scaffold Architecture on the Distribution of Surface Strains and Fluid Flow Shear Stresses and Expected Osteochondral Cell Differentiation

    Science.gov (United States)

    Hendrikson, Wim J.; Deegan, Anthony J.; Yang, Ying; van Blitterswijk, Clemens A.; Verdonschot, Nico; Moroni, Lorenzo; Rouwkema, Jeroen

    2017-01-01

    Scaffolds for regenerative medicine applications should instruct cells with the appropriate signals, including biophysical stimuli such as stress and strain, to form the desired tissue. Apart from that, scaffolds, especially for load-bearing applications, should be capable of providing mechanical stability. Since both scaffold strength and stress–strain distributions throughout the scaffold depend on the scaffold’s internal architecture, it is important to understand how changes in architecture influence these parameters. In this study, four scaffold designs with different architectures were produced using additive manufacturing. The designs varied in fiber orientation, while fiber diameter, spacing, and layer height remained constant. Based on micro-CT (μCT) scans, finite element models (FEMs) were derived for finite element analysis (FEA) and computational fluid dynamics (CFD). FEA of scaffold compression was validated using μCT scan data of compressed scaffolds. Results of the FEA and CFD showed a significant impact of scaffold architecture on fluid shear stress and mechanical strain distribution. The average fluid shear stress ranged from 3.6 mPa for a 0/90 architecture to 6.8 mPa for a 0/90 offset architecture, and the surface shear strain from 0.0096 for a 0/90 offset architecture to 0.0214 for a 0/90 architecture. This subsequently resulted in variations of the predicted cell differentiation stimulus values on the scaffold surface. Fluid shear stress was mainly influenced by pore shape and size, while mechanical strain distribution depended mainly on the presence or absence of supportive columns in the scaffold architecture. Together, these results corroborate that scaffold architecture can be exploited to design scaffolds with regions that guide specific tissue development under compression and perfusion. In conjunction with optimization of stimulation regimes during bioreactor cultures, scaffold architecture optimization can be used to improve

  1. Influence of Additive Manufactured Scaffold Architecture on the Distribution of Surface Strains and Fluid Flow Shear Stresses and Expected Osteochondral Cell Differentiation.

    Science.gov (United States)

    Hendrikson, Wim J; Deegan, Anthony J; Yang, Ying; van Blitterswijk, Clemens A; Verdonschot, Nico; Moroni, Lorenzo; Rouwkema, Jeroen

    2017-01-01

    Scaffolds for regenerative medicine applications should instruct cells with the appropriate signals, including biophysical stimuli such as stress and strain, to form the desired tissue. Apart from that, scaffolds, especially for load-bearing applications, should be capable of providing mechanical stability. Since both scaffold strength and stress-strain distributions throughout the scaffold depend on the scaffold's internal architecture, it is important to understand how changes in architecture influence these parameters. In this study, four scaffold designs with different architectures were produced using additive manufacturing. The designs varied in fiber orientation, while fiber diameter, spacing, and layer height remained constant. Based on micro-CT (μCT) scans, finite element models (FEMs) were derived for finite element analysis (FEA) and computational fluid dynamics (CFD). FEA of scaffold compression was validated using μCT scan data of compressed scaffolds. Results of the FEA and CFD showed a significant impact of scaffold architecture on fluid shear stress and mechanical strain distribution. The average fluid shear stress ranged from 3.6 mPa for a 0/90 architecture to 6.8 mPa for a 0/90 offset architecture, and the surface shear strain from 0.0096 for a 0/90 offset architecture to 0.0214 for a 0/90 architecture. This subsequently resulted in variations of the predicted cell differentiation stimulus values on the scaffold surface. Fluid shear stress was mainly influenced by pore shape and size, while mechanical strain distribution depended mainly on the presence or absence of supportive columns in the scaffold architecture. Together, these results corroborate that scaffold architecture can be exploited to design scaffolds with regions that guide specific tissue development under compression and perfusion. In conjunction with optimization of stimulation regimes during bioreactor cultures, scaffold architecture optimization can be used to improve

  2. Photo-active collagen systems with controlled triple helix architecture.

    Science.gov (United States)

    Tronci, Giuseppe; Russell, Stephen J; Wood, David J

    2013-08-14

    The design of photo-active collagen systems is presented as a basis for establishing biomimetic materials with varied network architecture and programmable macroscopic properties. Following in-house isolation of type I collagen, reaction with vinyl-bearing compounds of varied backbone rigidity, i.e. 4-vinylbenzyl chloride (4VBC) and glycidyl methacrylate (GMA), was carried out. TNBS colorimetric assay, (1)H-NMR and ATR-FTIR confirmed covalent and tunable functionalization of collagen lysines. Depending on the type and extent of functionalization, controlled stability and thermal denaturation of triple helices were observed via circular dichroism (CD), whereby the hydrogen-bonding capability of introduced moieties was shown to play a major role. Full gel formation was observed following photo-activation of functionalized collagen solutions. The presence of a covalent network only slightly affected collagen triple helix conformation (as observed by WAXS and ATR-FTIR), confirming the structural organization of functionalized collagen precursors. Photo-activated hydrogels demonstrated an increased denaturation temperature (DSC) with respect to native collagen, suggesting that the formation of the covalent network successfully stabilized collagen triple helices. Moreover, biocompatibility and mechanical competence of obtained hydrogels were successfully demonstrated under physiologically-relevant conditions. These results demonstrate that this novel synthetic approach enabled the formation of biocompatible collagen systems with defined network architecture and programmable macroscopic properties, which can only partially be obtained with current synthetic methods.

  3. Survey of US Department of Defense Manufacturing Technology Program activities applicable to civilian manufacturing industries. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Azimi, S.A.; Conrad, J.L.; Reed, J.E.

    1985-03-01

    Intent of the survey was to identify and characterize activities potentially applicable to improving energy efficiency and overall productivity in the civilian manufacturing industries. The civilian industries emphasized were the general manufacturing industries (including fabricated metals, glass, machinery, paper, plastic, textile, and transportation equipment manufacturing) and the primary metals industries (including primary aluminum, copper, steel, and zinc production). The principal steps in the survey were to: develop overview taxonomies of the general manufacturing and primary metals industries as well as specific industry taxonomies; identify needs and opportunities for improving process energy efficiency and productivity in the industries included; identify federal programs, capabilities, and special technical expertise that might be relevant to industry's needs and opportunities; contact federal laboratories/facilities, through visits and other forms of inquiry; prepare formatted profiles (descriptions) potentially applicable work efforts; review findings with industry; and compile and evaluate industry responses.

  4. Photo-active collagen systems with controlled triple helix architecture

    CERN Document Server

    Tronci, Giuseppe; Wood, David J

    2013-01-01

    The design of photo-active collagen systems is presented as a basis for establishing biomimetic materials with varied network architecture and programmable macroscopic properties. Following in-house isolation of type I collagen, reaction with vinyl-bearing compounds of varied backbone rigidity, i.e. 4-vinylbenzyl chloride (4VBC) and glycidyl methacrylate (GMA), was carried out. TNBS colorimetric assay, 1H-NMR and ATR-FTIR confirmed covalent and tunable functionalization of collagen lysines. Depending on the type and extent of functionalization, controlled stability and thermal denaturation of triple helices were observed via circular dichroism (CD), whereby the hydrogen-bonding capability of introduced moieties was shown to play a major role. Full gel formation was observed following photo-activation of functionalized collagen solutions. The presence of a covalent network only slightly affected collagen triple helix conformation (as observed by WAXS and ATR-FTIR), confirming the structural organization of fun...

  5. A distributed architecture for activating the peripheral nervous system

    Science.gov (United States)

    Andreu, David; Guiraud, David; Souquet, Guillaume

    2009-04-01

    We present a new system for functional electrical stimulation (FES) applications based on networked stimulation units. They embed an advanced analog circuit, which provides multipolar and multiphasic stimulation profiles, and digital circuits, which ensure safety, locally executed programmed profiles, and communication with the master controller. This architecture is thus based on distributed stimulation units (DSU) that need only a two-wire bus to communicate, regardless of the number of poles of each DSU-driven electrode. This structure minimizes the required bandwidth between master and distributed units, increases the safety and stimulation features and decreases the complexity of the surgical approach. We have successfully tested this network-based stimulation architecture on benchtop stimulators. This original approach allows broad exploration of all possible methods to stimulate peripheral nerves, particularly in the goal of restoring the motor function. It provides a powerful research device to determine the optimal, least aggressive and the most efficient way to activate the peripheral nervous system using an implanted FES system that is less invasive than other existing devices.

  6. A distributed architecture for activating the peripheral nervous system.

    Science.gov (United States)

    Andreu, David; Guiraud, David; Souquet, Guillaume

    2009-04-01

    We present a new system for functional electrical stimulation (FES) applications based on networked stimulation units. They embed an advanced analog circuit, which provides multipolar and multiphasic stimulation profiles, and digital circuits, which ensure safety, locally executed programmed profiles, and communication with the master controller. This architecture is thus based on distributed stimulation units (DSU) that need only a two-wire bus to communicate, regardless of the number of poles of each DSU-driven electrode. This structure minimizes the required bandwidth between master and distributed units, increases the safety and stimulation features and decreases the complexity of the surgical approach. We have successfully tested this network-based stimulation architecture on benchtop stimulators. This original approach allows broad exploration of all possible methods to stimulate peripheral nerves, particularly in the goal of restoring the motor function. It provides a powerful research device to determine the optimal, least aggressive and the most efficient way to activate the peripheral nervous system using an implanted FES system that is less invasive than other existing devices.

  7. Overview of additive manufacturing activities at MTU aero engines

    Science.gov (United States)

    Bamberg, Joachim; Dusel, Karl-Heinz; Satzger, Wilhelm

    2015-03-01

    Additive Manufacturing (AM) is a promising technology to produce parts easily and effectively, just by using metallic powder or wire as starting material and a sophisticated melting process. In contrast to milling or turning technologies complex shaped and hollow parts can be built up in one step. That reduces the production costs and allows the implementation of complete new 3D designs. Therefore AM is also of great interest for aerospace and aero engine industry. MTU Aero Engines has focused its AM activities to the selective laser melting technique (SLM). This technique uses metallic powder and a laser for melting and building up the part layer by layer. It is shown which lead part was selected for AM and how the first production line was established. A special focus is set on the quality assurance of the selective laser melting process. In addition to standard non-destructive inspection techniques a new online monitoring tool was developed and integrated into the SLM machines. The basics of this technique is presented.

  8. SOME IMPORTANT FACTORS AFFECTING EVOLUTION OF ACTIVITY BASED COSTING (ABC SYSTEM IN EGYPTIAN MANUFACTURING FIRMS

    Directory of Open Access Journals (Sweden)

    Karim MAMDOUH ABBAS

    2014-04-01

    Full Text Available The present investigation aims to determine the factors affecting evolution of Activity Based Costing (ABC system in Egyptian case. The study used the survey method to describe and analyze these factors in some Egyptian firms. The population of the study is Egyptian manufacturing firms. Accordingly, the number of received questionnaires was 392 (23 Egyptian manufacturing firms in the first half of 2013. Finally, the study stated some influencing factors for evolution this system (ABC in Egyptian manufacturing firms.

  9. Methodologies for Active Aging in the Manufacturing Sector

    Science.gov (United States)

    Fornasiero, Rosanna; Berdicchia, Domenica; Zambelli, Mario; Masino, Giovanni

    The research project named “Flexibly Beyond” studied and experimented innovative models for the enhancement of the role of senior workers and prolongation of their working life. The research was based on the application of innovative methods and tools to the ageing society and in particular to the European manufacturing companies represented in the project by apparel and footwear sectors. The project was funded under the Innovative Measures of the art.6 of the European Social Fund (VS/2006/0353) and coordinated by Politecnico Calzaturiero. The real strength of the project was the large network including all the actors of the value chain which allows transferring the theoretical findings to practical level in SMEs manufacturing context.

  10. Activate: Social Action in landscape Architecture Design Education

    Directory of Open Access Journals (Sweden)

    Helen Mclean

    2004-06-01

    Full Text Available This paper is a reflection on the teaching approach adopted in two landscape architecture design studios where students were engaged in developing design projects and campaign strategies informed by personal understandings of action and advocacy for and with communities. The approach was a deliberate application of principles from advocacy theory enmeshed in an educational philosophy of learner-centeredness and the intent was for students to develop strong individual senses of awareness and empowerment in an environment that value personal interests and learning. An evaluation of the approach as an attempt to position landscape architecture as social practice is provided.

  11. TSCA Chemical Data Reporting Fact Sheet: Reporting Manufactured Chemical Substances from Metal Mining and Related Activities

    Science.gov (United States)

    This fact sheet provides guidance on the Chemical Data Reporting (CDR) rule requirements related to the reporting of mined metals, intermediates, and byproducts manufactured during metal mining and related activities.

  12. 支持跨粒度重构的制造执行系统体系结构%Manufacturing execution system architecture supporting cross-grain reconfiguration

    Institute of Scientific and Technical Information of China (English)

    黄毅; 郑力; 向晴; 危凯权

    2011-01-01

    To enable Manufacturing Execution Systems (MES) keep working well with related production systems, i.e.response to more intensive & more complicated reconfiguration demand, a Reconfigurable Manufacturing Execution Systems Architecture (RMESA) supporting cross-grained reconfiguration was proposed.Based on reconfiguration demand details, technologies such as domain driven and modularization design were used to decompose MES into module layers with definite responsibility and grain dissimilarity.Main architecture of upper layer was generalized to reduce MES complexity, and modules in lower layer were generalized to collect reusable modules to support modeling in strong cohesion and low coupling.Finally, the proposed architecture was proved to be effective by application example.%为保持制造执行系统与生产系统同步,以响应更密集、更复杂的制造执行系统重构需求,提出一套支持跨粒度重构的制造执行系统体系结构.该结构基于重构需求细节,使用领域驱动设计、模块化设计等技术,将制造执行系统解构为职责明确、粒度相异的模块层级,一方面归纳通用的上层模块主体框架以有效分割制造执行系统的复杂度,另一方面归纳标准的下层模块以支持高内聚、低耦合的模型复用.通过在实际案例中的应用,验证了所提体系结构的有效性.

  13. International Conference on Harmonisation; guidance on good manufacturing practice for active pharmaceutical ingredients; availability. Notice.

    Science.gov (United States)

    2001-09-25

    The Food and Drug Administration (FDA) is announcing the availability of a guidance entitled "Q7A Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients." The guidance was prepared under the auspices of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The guidance describes current good manufacturing practice (CGMP) for manufacturing of active pharmaceutical ingredients (APIs). The guidance is intended to help ensure that all APIs meet the standards for quality and purity they purport or are represented to possess.

  14. Molecular analysis of plant architecture in Arabidopsis thaliana using activation tagging.

    NARCIS (Netherlands)

    Chalfun Junior, A.

    2004-01-01

    Keywords: Arabidopsisthaliana, activation tagging, T-DNA, transposon, mutants, enhancer, DNA methylation, plant architecture, development, forward/reverse genetics, lateral organs, flower, vascular tissue, HLH, transmembrane, transcription factorsPlant development is one of the mos

  15. A method of manufacturing process modeling based on activity network for large-sized and complex products

    Institute of Scientific and Technical Information of China (English)

    LV Min; TONG Zhen-bo; WANG Gang

    2008-01-01

    Simulation technique is an efficient approach to realize the planning and scheduling of manufacturing process of products. An appropriate and efficient manufacturing process model is the basis and key of manufac-turing process simulation. By analyzing the features of large-sized and complex products, a method of manufac-turing process modeling based on activity network is presented and a mapping algorithm of translating BOM/ BOP into the manufacturing process model is designed in detail.

  16. BIO-INSPIRED SELF-ADAPTIVE MANUFACTURING SYSTEM CONTROL ARCHITECTURE%类生物化自适应制造系统控制结构

    Institute of Scientific and Technical Information of China (English)

    王雷; 唐敦兵; 万敏; 袁伟东; 许美健

    2009-01-01

    未来的制造系统需要应对多变的不可预测环境的干扰,因此要求制造系统的控制结构具有较好的自适应性、自组织性、敏捷性、智能性和鲁棒性.而具有这些生物行为特征的类生物化制造系统能够很好的满足这一要求.因此,借鉴生物系统的组织结构、控制机理和运行模式,从一个全新角度提出了有机制造单元的概念,并结合基于激素分泌调节的超短反馈机制,建立了类生物化生产系统自适应控制模型;基于神经-内分泌-免疫系统调节机制,建立了类生物化自适应制造系统控制结构模型.最后,通过一个基于信息素通信机制的实例表明:整个系统具有较强的鲁棒性.%Future manufacturing systems need to cope with frequent changes and disturbances, therefore their control architectures require constant adaptability, agility, stability, self-organization, intelligence, and robustness. Bio-inspired manufacturing system can well satisfy these requirements. For this purpose, by referencing the biological organization structure and the mechanism, a bio-inspired manufacturing cell is presented from a novel view, and then a bio-inspired self-adaptive manufacturing model is established based on the ultra-short feedback mechanism of the neuro-endocrine system. A bio-inspired self-adaptive manufacturing system coordinated model is also established based on the neuro-endocrine-immunity system (NEIS). Finally, an example based on pheromone communication mechanism indicates that the robustness of the whole manufacturing system is improved by bio-inspired technologies.

  17. An Architecture of Active Learning SVMs with Relevance Feedback for Classifying E-mail

    CERN Document Server

    Islam, Md Saiful

    2010-01-01

    In this paper, we have proposed an architecture of active learning SVMs with relevance feedback (RF)for classifying e-mail. This architecture combines both active learning strategies where instead of using a randomly selected training set, the learner has access to a pool of unlabeled instances and can request the labels of some number of them and relevance feedback where if any mail misclassified then the next set of support vectors will be different from the present set otherwise the next set will not change. Our proposed architecture will ensure that a legitimate e-mail will not be dropped in the event of overflowing mailbox. The proposed architecture also exhibits dynamic updating characteristics making life as difficult for the spammer as possible.

  18. KNOWLEDGE MANAGEMENT FOR MAINTENANCE ACTIVITIES IN THE MANUFACTURING SECTOR

    Directory of Open Access Journals (Sweden)

    M.A. Mansor

    2012-06-01

    Full Text Available Maintenance is an indispensable part of the business process and plays an important role in an organisation’s success and survival. The main purpose of maintenance is to ensure equipment functions at its original optimal level. Thus, the knowledge and skills of operators are crucial and in demand. This paper presents a knowledge management of maintenance activities transfer method. Knowledge management is a process that a company cannot avoid, because it is a step in providing the necessary information for business performance measurements. Based on the example of a knowledge management system for a consultant company, we propose a knowledge repository or warehouse for maintenance activities that consists of four elements: best practice, databases, discussion forums and assessment tools. Each element has its own role and contribution towards better maintenance activities. Therefore, knowledge management has a deep relationship with performance evaluation or measurement.

  19. Do Changes in Muscle Architecture Affect Post-Activation Potentiation?

    Directory of Open Access Journals (Sweden)

    Danielle Reardon, Jay R. Hoffman, Gerald T. Mangine, Adam J. Wells, Adam M. Gonzalez, Adam R. Jajtner, Jeremy R. Townsend, William P. McCormack, Jeffrey R. Stout, Maren S. Fragala, David H. Fukuda

    2014-09-01

    Full Text Available The purpose of this randomized, cross-over design study was to examine the effect of three different muscle potentiation protocols on acute changes in muscle architecture and vertical jump performance. Eleven experienced, resistance trained men (25.2±3.6y completed three potentiation squat protocols using moderate intensity (MI; 75%, 3 sets x 10 repetitions, high intensity (HI; 90%, 3 sets x 3 repetitions and 100% (1RM; 1 set x 1repetition of their 1RM. In addition, all participants completed a control session (CTL in which no protocol was performed. During each testing session, muscle architecture and vertical jump testing were assessed at baseline (BL, 8min post (8P and 20min post (20P workout. Ultrasound measures included cross sectional area (CSA and pennation angle (PANG of both the rectus femoris (RF and vastus lateralis (VL. Following each ultrasound measure, peak vertical jump power (PVJP and mean (MVJP power was assessed using an accelerometer. Magnitude based inferences were used to make comparisons between trials. The MI trial resulted in a likely greater increase from BL to 8P and 20P in RF-CSA and VL-CSA, while the HI trial resulted in a likely greater change from BL to 20P in both RF-CSA and VL-CSA. Meanwhile, changes in PVJP and MVJP for the MI trial was likely decreased at BL-8P and BL–20P, while the HI trial was shown to result in a likely or possible decrease compared to CTL at BL-8P and BL–20P, respectively. A likely negative relationship was observed between changes in VL-PANG and MVJP (r = -0.35; p , 0.018 at BL-8P, and between changes in PVJP and RF-CSA (r = -0.37; p , 0.014 at BL–20P. Results of this study were unable to demonstrate any potentiation response from the trials employed, however these protocols did result in acute muscle architectural changes.

  20. Space Industrialization: Manufacturing and Construction Activities. Part 2.

    Science.gov (United States)

    Story, Charles H.

    1983-01-01

    Discusses how space industrialization will provide direct benefits for our nation and will transfer technology to the many diverse areas of human activity. Examples are the development of the Space Shuttle, the Space Studies Institute, and the LS Society (advocates for colonizing space). (NRJ)

  1. Industry 4.0 implies lean manufacturing: Research activities in industry 4.0 function as enablers for lean manufacturing

    OpenAIRE

    Adam Sanders; Chola Elangeswaran; Jens Wulfsberg

    2016-01-01

    Purpose: Lean Manufacturing is widely regarded as a potential methodology to improve productivity and decrease costs in manufacturing organisations. The success of lean manufacturing demands consistent and conscious efforts from the organisation, and has to overcome several hindrances. Industry 4.0 makes a factory smart by applying advanced information and communication systems and future-oriented technologies. This paper analyses the incompletely perceived link between Industr...

  2. Technological review of the HRP manufacturing process R and D activity

    Energy Technology Data Exchange (ETDEWEB)

    Visca, Eliseo, E-mail: eliseo.visca@enea.it [Associazione EURATOM-ENEA sulla Fusione, C.R. Frascati, Via E. Fermi 45, IT-00044 Frascati (Italy); Pizzuto, A. [Associazione EURATOM-ENEA sulla Fusione, C.R. Frascati, Via E. Fermi 45, IT-00044 Frascati (Italy); Gavila, P.; Riccardi, B. [Fusion For Energy, C. Josep Pla 2, ES-08019 Barcelona (Spain); Roccella, S. [Associazione EURATOM-ENEA sulla Fusione, C.R. Frascati, Via E. Fermi 45, IT-00044 Frascati (Italy); Candura, D.; Sanguinetti, G.P. [Ansaldo Nucleare S.p.A., Corso Perrone 25, IT-16121 Genova (Italy)

    2013-10-15

    Highlights: • R and D activities for the manufacturing of ITER divertor high heat flux plasma-facing components (HHFC). • ENEA and Ansaldo have jointly manufactured several actively cooled monoblock mock-ups and prototypical components. • Successful manufacturing by HRP (hot radial pressing) and PBC (pre-brazed casting) of both W and CFC armoured small and medium scale mockups. • ENEA-ANSALDO participate to the European programme for the qualification of the manufacturing technology for the ITER divertor IVT. • A qualification divertor inner vertical target prototype successfully tested at ITER relevant thermal heat fluxes. -- Abstract: ENEA and Ansaldo Nucleare S.p.A. have been deeply involved in the European International Thermonuclear Experimental Reactor (ITER) R and D activities for the manufacturing of high heat flux plasma-facing components (HHFC), and in particular for the inner vertical target (IVT) of the ITER divertor. This component has to be manufactured by using both armour and structural materials whose properties are defined by ITER. Their physical properties prevent the use of standard joining techniques. The reference armour materials are tungsten and carbon/carbon fibre composite (CFC). The cooling pipe is made of copper alloy (CuCrZr-IG). During the last years ENEA and Ansaldo have jointly manufactured several actively cooled monoblock mock-ups and prototypical components of different length, geometry and materials, by using innovative processes: HRP (hot radial pressing) and PBC (pre-brazed casting). The history of the technical issues solved during the R and D phase and the improvements implemented to the assembling tools and equipments are reviewed in the paper together with the testing results. The optimization of the processes started from the successful manufacturing of both W and CFC armoured small scale mockups thermal fatigue tested in the worst ITER operating condition (20 MW/m{sup 2}) through the achievement of record

  3. [Determination of the biological activity of aminoglycoside antibiotics on a dry nutrient medium of Soviet manufacture].

    Science.gov (United States)

    Grigor'eva, V M; Andreeva, Z M; Astanina, L N; Shiriaeva, V L; Gridneva, N I

    1981-06-01

    Possible use of the dry nutrient medium manufactured in the USSR for the assay of aminoglycoside antibiotic activity with the agar diffusion method was studied. The optimal conditions for the antibiotic activity assay on this medium were developed. The dry nutrient medium may be used for the activity assay of the aminoglycoside antibiotics, i. e. streptomycin sulfate, dihydrostreptomycin sulfate, neomycin sulfate, monomycin and gentamicin sulfate.

  4. Milk catalase activity as an indicator of thermization treatments used in the manufacture of cheddar cheese.

    Science.gov (United States)

    Hirvi, Y; Griffiths, M W

    1998-02-01

    Pilot-scale studies were carried out to determine the effect of different heat treatments on catalase activity during the manufacture and maturation of Cheddar cheese. Three trials were conducted to monitor catalase activity using disk flotation and polarographic methods. Cheese was manufactured from raw milk and from milk that had been treated at 60, 65 and 72 degrees C for 16 s using a high temperature, short time heat exchanger. Catalase activity was also determined in samples of commercial milk and in samples of mild, medium, sharp, and extra sharp Cheddar cheeses obtained from different manufacturers in order to verify that the enzyme could be used as an indicator of the type of heat treatment applied to cheese milk. Catalase activity was present in cheese made from raw milk but was only present at low concentrations in cheese manufactured from thermized milk. However, high catalase activity was observed in commercial samples of sharp and extra sharp Cheddar cheese that was apparently due to the growth of catalase-producing yeasts in the cheese during maturation.

  5. Industry 4.0 implies lean manufacturing: Research activities in industry 4.0 function as enablers for lean manufacturing

    Directory of Open Access Journals (Sweden)

    Adam Sanders

    2016-09-01

    Full Text Available Purpose: Lean Manufacturing is widely regarded as a potential methodology to improve productivity and decrease costs in manufacturing organisations. The success of lean manufacturing demands consistent and conscious efforts from the organisation, and has to overcome several hindrances. Industry 4.0 makes a factory smart by applying advanced information and communication systems and future-oriented technologies. This paper analyses the incompletely perceived link between Industry 4.0 and lean manufacturing, and investigates whether Industry 4.0 is capable of implementing lean. Executing Industry 4.0 is a cost-intensive operation, and is met with reluctance from several manufacturers. This research also provides an important insight into manufacturers’ dilemma as to whether they can commit into Industry 4.0, considering the investment required and unperceived benefits. Design/methodology/approach: Lean manufacturing is first defined and different dimensions of lean are presented. Then Industry 4.0 is defined followed by representing its current status in Germany. The barriers for implementation of lean are analysed from the perspective of integration of resources. Literatures associated with Industry 4.0 are studied and suitable solution principles are identified to solve the abovementioned barriers of implementing lean. Findings: It is identified that researches and publications in the field of Industry 4.0 held answers to overcome the barriers of implementation of lean manufacturing. These potential solution principles prove the hypothesis that Industry 4.0 is indeed capable of implementing lean. It uncovers the fact that committing into Industry 4.0 makes a factory lean besides being smart. Originality/value: Individual researches have been done in various technologies allied with Industry 4.0, but the potential to execute lean manufacturing was not completely perceived. This paper bridges the gap between these two realms, and identifies

  6. Design of phosphorylated dendritic architectures to promote human monocyte activation.

    Science.gov (United States)

    Poupot, Mary; Griffe, Laurent; Marchand, Patrice; Maraval, Alexandrine; Rolland, Olivier; Martinet, Ludovic; L'Faqihi-Olive, Fatima-Ezzahra; Turrin, Cédric-Olivier; Caminade, Anne-Marie; Fournié, Jean-Jacques; Majoral, Jean-Pierre; Poupot, Rémy

    2006-11-01

    As first defensive line, monocytes are a pivotal cell population of innate immunity. Monocyte activation can be relevant to a range of immune conditions and responses. Here we present new insights into the activation of monocytes by a series of phosphonic acid-terminated, phosphorus-containing dendrimers. Various dendritic or subdendritic structures were synthesized and tested, revealing the basic structural requirements for monocyte activation. We showed that multivalent character and phosphonic acid capping of dendrimers are crucial for monocyte targeting and activation. Confocal videomicroscopy showed that a fluorescein-tagged dendrimer binds to isolated monocytes and gets internalized within a few seconds. We also found that dendrimers follow the phagolysosomial route during internalization by monocytes. Finally, we performed fluorescence resonance energy transfer (FRET) experiments between a specifically designed fluorescent dendrimer and phycoerythrin-coupled antibodies. We showed that the typical innate Toll-like receptor (TLR)-2 is clearly involved, but not alone, in the sensing of dendrimers by monocytes. In conclusion, phosphorus-containing dendrimers appear as precisely tunable nanobiotools able to target and activate human innate immunity and thus prove to be good candidates to develop new drugs for immunotherapies.

  7. Physical activity support community togetheractive - architecture, implementation and evaluation

    NARCIS (Netherlands)

    Elloumi, Lamia; Beijnum, van Bert-Jan; Hermens, Hermie

    2015-01-01

    Reducing sedentary lifestyle and physical inactivity is getting an increased attention of researchers and health organizations due to its significant benefits on health. In the same direction we are proposing a virtual community system, TogetherActive, which supports people in their daily physical a

  8. A control architecture to coordinate distributed generators and active power filters coexisting in a microgrid

    DEFF Research Database (Denmark)

    Hashempour, Mohammad M.; Savaghebi, Mehdi; Quintero, Juan Carlos Vasquez

    2016-01-01

    This paper proposes a control architecture of distributed generators (DGs) inverters and shunt active power filters (APFs) in microgrids to compensate voltage harmonics in a coordinated way. For this, a hierarchical control structure is proposed that includes two control levels. The primary (local...

  9. A Control Architecture to Coordinate Distributed Generators and Active Power Filters Coexisting in a Microgrid

    DEFF Research Database (Denmark)

    Hashempour, Mohammad M.; Firoozabadi, Mehdi Savaghebi; Quintero, Juan Carlos Vasquez

    2016-01-01

    This paper proposes a control architecture of distributed generators (DGs) inverters and shunt active power filters (APFs) in microgrids to compensate voltage harmonics in a coordinated way. For this, a hierarchical control structure is proposed that includes two control levels. The primary (local...

  10. Three-dimensional architecture of lithium-anodes made from graphite fibers coated with thin-films of silicon oxycarbide: Design, performance and manufacturability

    Science.gov (United States)

    Saleh, Ibrahim; Raj, Rishi

    2016-04-01

    Silicon oxycarbide (SiCO) is an amorphous molecular network of Sisbnd Csbnd O tetrahedra anchored to graphene-like carbon. The graphene forms a three dimensional cellular network with a domain size of ∼5 nm. Therefore nanometer thick films of SiCO grown on graphite may be expected to have unusual behavior. We grow these films on a bed of commercially available graphite fibers that serve the dual function of a current collector. The electrochemical behavior of the composite is measured as a function of the thickness of the SiCO films. Thick films approach the typical behavior of bulk SiCO (which has three times the capacity of graphite, but suffers from poor first cycle efficiency). However, films, approximately 100 nm thick, show high first cycle efficiency as well as high capacity. The composite performs better than the prediction from the rule-of-mixtures, which further substantiates the unusual behavior of the thin-film architecture. The Raman spectra of these thin films also differ from bulk SiCO. The development of thin graphite fibers, with a high surface to volume ratio that have the same capacity as the current graphite-powder technology, coupled with manufacturing of these thin-films by a liquid-polymer precursor based process, can propel these results toward commercialization.

  11. Hierarchical nitrogen doped bismuth niobate architectures: Controllable synthesis and excellent photocatalytic activity

    Energy Technology Data Exchange (ETDEWEB)

    Hou, Jungang, E-mail: lorinhjg@yahoo.com.cn [School of Metallurgical and Ecological Engineering, University of Science and Technology Beijing, Beijing 100083 (China); Cao, Rui; Wang, Zheng [School of Metallurgical and Ecological Engineering, University of Science and Technology Beijing, Beijing 100083 (China); Jiao, Shuqiang, E-mail: sjiao@ustb.edu.cn [School of Metallurgical and Ecological Engineering, University of Science and Technology Beijing, Beijing 100083 (China); Zhu, Hongmin [School of Metallurgical and Ecological Engineering, University of Science and Technology Beijing, Beijing 100083 (China)

    2012-05-30

    Graphical abstract: Efficient visible-light-driven photocatalysts of peony-like nitrogen doped Bi{sub 3}NbO{sub 7} hierarchical architectures and silver-layered Bi{sub 3}NbO{sub 7-x}Nx heterostructures were successfully synthesized in this discovery. Highlights: Black-Right-Pointing-Pointer N-Bi{sub 3}NbO{sub 7} architectures were synthesized via two-step hydrothermal process. Black-Right-Pointing-Pointer Electronic structure calculations indicated that N replaced O in samples. Black-Right-Pointing-Pointer Growth mechanism is proposed for transformation of nanoparticles to microflowers. Black-Right-Pointing-Pointer Excellent activities of N-Bi{sub 3}NbO{sub 7} architectures were obtained for degradation. Black-Right-Pointing-Pointer Enhanced photocatalytic performance was observed for Ag/N-Bi{sub 3}NbO{sub 7} architectures. - Abstract: Nitrogen doped bismuth niobate (N-Bi{sub 3}NbO{sub 7}) hierarchical architectures were synthesized via a facile two-step hydrothermal process. XRD patterns revealed that the defect fluorite-type crystal structure of Bi{sub 3}NbO{sub 7} remained intact upon nitrogen doping. Electron microscopy showed the N-Bi{sub 3}NbO{sub 7} architecture has a unique peony-like spherical superstructure composed of numerous nanosheets. UV-vis spectra indicated that nitrogen doping in the compound results in a red-shift of the absorption edge from 450 nm to 470 nm. XPS indicated that [Bi/Nb]-N bonds were formed by inducing nitrogen to replace a small amount of oxygen in Bi{sub 3}NbO{sub 7-x}N{sub x}, which is explained by electronic structure calculations including energy band and density of states. Based on observations of architectures formation, a possible growth mechanism was proposed to explain the transformation of polyhedral-like nanoparticles to peony-like microflowers via an Ostwald riping mechanism followed by self-assembly. The N-Bi{sub 3}NbO{sub 7} architectures due to the large specific surface area and nitrogen doping exhibited higher

  12. Manufacture of magnetically active fiber-reinforced composites for use in power generation

    Science.gov (United States)

    Etches, Julie; Bond, Ian; Mellor, Phil

    2004-07-01

    A major issue yet to be resolved for embedding sensors, actuators and microelectromechanical systems (MEMS) in 'smart' structures is that of providing power. Work is ongoing in the field with examples of micro battery technology, use of solar power and micro fuel cells. The work presented here considers a technology to enable the development of integrated power generation and actuation. Magnetic fibre reinforced composite material has been developed which utilises hollow glass fibres filled with active magnetic material. The resulting material maintains structural integrity as well as providing a possible means of electrical power generation from a dynamically loaded structure. The hollow glass fibres were manufactured in-house using a bespoke fibre drawing facility. Hard magnetic powder materials were introduced into the hollow fibre cores to provide an active electromagnetic function. This paper will discuss the manufacture, characterization and optimisation of active magnetic fibre reinforced composite materials.

  13. A RSC/nucleosome complex determines chromatin architecture and facilitates activator binding.

    Science.gov (United States)

    Floer, Monique; Wang, Xin; Prabhu, Vidya; Berrozpe, Georgina; Narayan, Santosh; Spagna, Dan; Alvarez, David; Kendall, Jude; Krasnitz, Alexander; Stepansky, Asya; Hicks, James; Bryant, Gene O; Ptashne, Mark

    2010-04-30

    How is chromatin architecture established and what role does it play in transcription? We show that the yeast regulatory locus UASg bears, in addition to binding sites for the activator Gal4, sites bound by the RSC complex. RSC positions a nucleosome, evidently partially unwound, in a structure that facilitates Gal4 binding to its sites. The complex comprises a barrier that imposes characteristic features of chromatin architecture. In the absence of RSC, ordinary nucleosomes encroach over the UASg and compete with Gal4 for binding. Taken with our previous work, the results show that both prior to and following induction, specific DNA-binding proteins are the predominant determinants of chromatin architecture at the GAL1/10 genes. RSC/nucleosome complexes are also found scattered around the yeast genome. Higher eukaryotic RSC lacks the specific DNA-binding determinants found on yeast RSC, and evidently Gal4 works in those organisms despite whatever obstacle broadly positioned nucleosomes present.

  14. ACTIVITY-BASED COSTING DAN SIMULATED ANNEALING UNTUK PENCARIAN RUTE PADA FLEXIBLE MANUFACTURING SYSTEMS

    Directory of Open Access Journals (Sweden)

    Gregorius Satia Budhi

    2003-01-01

    Full Text Available Flexible Manufacturing System (FMS is a manufacturing system that is formed from several Numerical Controlled Machines combine with material handling system, so that different jobs can be worked by different machines sequences. FMS combine the high productivity and flexibility of Transfer Line and Job Shop manufacturing system. In this reasearch, Activity-Based Costing(ABC approach was used as the weight to search the operation route in the proper machine, so that the total production cost can be optimized. The search method that was used in this experiment is Simulated Annealling, a variant form Hill Climbing Search method. An ideal operation time to proses a part was used as the annealling schedule. From the empirical test, it could be proved that the use of ABC approach and Simulated Annealing to search the route (routing process can optimize the Total Production Cost. In the other hand, the use of ideal operation time to process a part as annealing schedule can control the processing time well. Abstract in Bahasa Indonesia : Flexible Manufacturing System (FMS adalah sistem manufaktur yang tersusun dari mesin-mesin Numerical Control (NC yang dikombinasi dengan Sistem Penanganan Material, sehingga job-job berbeda dikerjakan oleh mesin-mesin dengan alur yang berlainan. FMS menggabungkan produktifitas dan fleksibilitas yang tinggi dari Sistem Manufaktur Transfer Line dan Job Shop. Pada riset ini pendekatan Activity-Based Costing (ABC digunakan sebagai bobot / weight dalam pencarian rute operasi pada mesin yang tepat, untuk lebih mengoptimasi biaya produksi secara keseluruhan. Adapun metode Searching yang digunakan adalah Simulated Annealing yang merupakan varian dari metode searching Hill Climbing. Waktu operasi ideal untuk memproses sebuah part digunakan sebagai Annealing Schedulenya. Dari hasil pengujian empiris dapat dibuktikan bahwa penggunaan pendekatan ABC dan Simulated Annealing untuk proses pencarian rute (routing dapat lebih

  15. Archaeal promoter architecture and mechanism of gene activation

    DEFF Research Database (Denmark)

    Peng, Nan; Ao, Xiang; Liang, Yun Xiang;

    2011-01-01

    Sulfolobus solfataricus and Sulfolobus islandicus contain several genes exhibiting D-arabinose-inducible expression and these systems are ideal for studying mechanisms of archaeal gene expression. At sequence level, only two highly conserved cis elements are present on the promoters: a regulatory...... element named ara box directing arabinose-inducible expression and the basal promoter element TATA, serving as the binding site for the TATA-binding protein. Strikingly, these promoters possess a modular structure that allows an essentially inactive basal promoter to be strongly activated. The invoked...

  16. Experimental investigation of active rib stitch knitted architecture for flow control applications

    Science.gov (United States)

    Abel, Julianna M.; Mane, Poorna; Pascoe, Benjamin; Luntz, Jonathan; Brei, Diann

    2010-04-01

    Actively manipulating flow characteristics around the wing can enhance the high-lift capability and reduce drag; thereby, increasing fuel economy, improving maneuverability and operation over diverse flight conditions which enables longer, more varied missions. Active knits, a novel class of cellular structural smart material actuator architectures created by continuous, interlocked loops of stranded active material, produce distributed actuation that can actively manipulate the local surface of the aircraft wing to improve flow characteristics. Rib stitch active knits actuate normal to the surface, producing span-wise discrete periodic arrays that can withstand aerodynamic forces while supplying the necessary displacement for flow control. This paper presents a preliminary experimental investigation of the pressuredisplacement actuation performance capabilities of a rib stitch active knit based upon shape memory alloy (SMA) wire. SMA rib stitch prototypes in both individual form and in stacked and nestled architectures were experimentally tested for their quasi-static load-displacement characteristics, verifying the parallel and series relationships of the architectural configurations. The various configurations tested demonstrated the potential of active knits to generate the required level of distributed surface displacements while under aerodynamic level loads for various forms of flow control.

  17. Activities of nicotinic acetylcholine receptors modulate neurotransmission and synaptic architecture

    Institute of Scientific and Technical Information of China (English)

    Akira Oda; Hidekazu Tanaka

    2014-01-01

    The cholinergic system is involved in a broad spectrum of brain function, and its failure has been implicated in Alzheimer’s disease. Acetylcholine transduces signals through muscarinic and nicotinic acetylcholine receptors, both of which inlfuence synaptic plasticity and cognition. However, the mechanisms that relate the rapid gating of nicotinic acetylcholine receptors to per-sistent changes in brain function have remained elusive. Recent evidence indicates that nicotinic acetylcholine receptors activities affect synaptic morphology and density, which result in per-sistent rearrangements of neural connectivity. Further investigations of the relationships between nicotinic acetylcholine receptors and rearrangements of neural circuitry in the central nervous system may help understand the pathogenesis of Alzheimer’s disease.

  18. Improvement of the Mechanism for the Management of Innovation Activity in the Manufacturing Industry

    Directory of Open Access Journals (Sweden)

    Vitalii Nikolaevich Makoveev

    2015-09-01

    Full Text Available The transition of Russia’s economy from raw materials exporting model of development to the innovation model is a national priority, since it contributes to intensive and sustainable economic growth and reduces economic dependence on external markets. GDP growth rate of 75–90% in the developed countries such as the USA, Japan, Germany, the UK, France, and also in the newly industrialized countries of Southeast Asia and China, is achieved due to the “progress of knowledge” – the intellectualization of the main production factors. Due to this fact, the increase in the standard of living in Russia, as well as overcoming its technological and economic lagging behind the more developed countries is possible only on the basis of the increase in productivity, enhancement of Russia’s competitiveness in international markets of innovative products, modernization and sustainable development of industrial enterprises through the creation of new innovation capabilities and the extensive utilization of that which have already been accumulated. The manufacturing industry is a powerful driving force of innovation economic development, since this sector concentrates the main production of the most technologically sophisticated and knowledgeintensive products with high added value. However, in the process of market transformations the products of domestic manufacturing enterprises have become much less competitive on international markets. There is a steady tendency toward the growth of imports and decrease of exports of enterprises of this sector. In this regard, the article identifies the factors that have the greatest influence on the development of innovation activities in the manufacturing industry. The author builds a multivariate regression model that determines the degree of influence of various socio-economic factors on the level of development of innovation activity in manufacturing. The paper proposes an organizational-economic mechanism

  19. Addressing fundamental architectural challenges of an activity-based intelligence and advanced analytics (ABIAA) system

    Science.gov (United States)

    Yager, Kevin; Albert, Thomas; Brower, Bernard V.; Pellechia, Matthew F.

    2015-06-01

    The domain of Geospatial Intelligence Analysis is rapidly shifting toward a new paradigm of Activity Based Intelligence (ABI) and information-based Tipping and Cueing. General requirements for an advanced ABIAA system present significant challenges in architectural design, computing resources, data volumes, workflow efficiency, data mining and analysis algorithms, and database structures. These sophisticated ABI software systems must include advanced algorithms that automatically flag activities of interest in less time and within larger data volumes than can be processed by human analysts. In doing this, they must also maintain the geospatial accuracy necessary for cross-correlation of multi-intelligence data sources. Historically, serial architectural workflows have been employed in ABIAA system design for tasking, collection, processing, exploitation, and dissemination. These simpler architectures may produce implementations that solve short term requirements; however, they have serious limitations that preclude them from being used effectively in an automated ABIAA system with multiple data sources. This paper discusses modern ABIAA architectural considerations providing an overview of an advanced ABIAA system and comparisons to legacy systems. It concludes with a recommended strategy and incremental approach to the research, development, and construction of a fully automated ABIAA system.

  20. ERECTA signaling controls Arabidopsis inflorescence architecture through chromatin-mediated activation of PRE1 expression.

    Science.gov (United States)

    Cai, Hanyang; Zhao, Lihua; Wang, Lulu; Zhang, Man; Su, Zhenxia; Cheng, Yan; Zhao, Heming; Qin, Yuan

    2017-03-13

    Flowering plants display a remarkable diversity in inflorescence architecture, and pedicel length is one of the key contributors to this diversity. In Arabidopsis thaliana, the receptor-like kinase ERECTA (ER) mediated signaling pathway plays important roles in regulating inflorescence architecture by promoting cell proliferation. However, the regulating mechanism remains elusive in the pedicel. Genetic interactions between ERECTA signaling and the chromatin remodeling complex SWR1 in the control of inflorescence architecture were studied. Comparative transcriptome analysis was applied to identify downstream components. Chromatin immunoprecipitation and nucleosome occupancy was further investigated. The results indicated that the chromatin remodeler SWR1 coordinates with ERECTA signaling in regulating inflorescence architecture by activating the expression of PRE1 family genes and promoting pedicel elongation. It was found that SWR1 is required for the incorporation of the H2A.Z histone variant into nucleosomes of the whole PRE1 gene family and the ERECTA controlled expression of PRE1 gene family through regulating nucleosome dynamics. We propose that utilization of a chromatin remodeling complex to regulate gene expression is a common theme in developmental control across kingdoms. These findings shed light on the mechanisms through which chromatin remodelers orchestrate complex transcriptional regulation of gene expression in coordination with a developmental cue.

  1. Aggregate size and architecture determine biomass activity for one-stage partial nitritation and anammox

    DEFF Research Database (Denmark)

    Vlaeminck, S.; Terada, Akihiko; Smets, Barth F.

    2010-01-01

    In partial nitritation/anammox systems, aerobic and anoxic ammonium-oxidizing bacteria (AerAOB and AnAOB) remove ammonium from wastewater. In this process, large granular microbial aggregates enhance the performance, but little is known about this type of granulation so far. In this study......, aggregates of three reactors (A, B, C) with different inoculation and operation were studied. The test objectives were to quantify the AerAOB and AnAOB abundance and the activity balance for the different aggregate sizes, and to relate aggregate morphology, size distribution, and architecture putatively...... to the inoculation and operation of the reactors. Fluorescent in-situ hybridization (FISH) was applied on aggregate sections to quantify AerAOB and AnAOB, as well as to visualize the aggregate architecture. The activity balance of the aggregates was calculated as the nitrite accumulation rate ratio (NARR), i...

  2. Active materials for adaptive architectural envelopes based on plant adaptation principles

    Directory of Open Access Journals (Sweden)

    Marlen Lopez

    2015-06-01

    Full Text Available In this paper, the authors present research into adaptive architectural envelopes that adapt to environmental changes using active materials, as a result of application of biomimetic principles from plants to architecture. Buildings use large amounts of energy in order to maintain their internal comfort, because conventional buildings are designed to provide a static design solution. Most of the current solutions for facades are not designed for optimum adaptation to contextual issues and needs, while biological solutions to adaptation are often complex, multi-functional and highly responsive. We focus on plant adaptations to the environment, as, due to their immobility, they have developed special means of protection against weather changing conditions. Furthermore, recent developments in new technologies are allowing the possibility to transfer these plant adaptation strategies to technical implementation. These technologies include: multi-material 3D printing, advances in materials science and new capabilities in simulation software. Unlike traditional mechanical activation used for dynamic systems in kinetic facades, adaptive architectural envelopes require no complex electronics, sensors, or actuators. The paper proposes a research of the relationship that can be developed between active materials and environmental issues in order to propose innovative and low-tech design strategies to achieve living envelopes according to plant adaptation principles.  

  3. Genome-wide binding analysis of the transcription activator ideal plant architecture1 reveals a complex network regulating rice plant architecture.

    Science.gov (United States)

    Lu, Zefu; Yu, Hong; Xiong, Guosheng; Wang, Jing; Jiao, Yongqing; Liu, Guifu; Jing, Yanhui; Meng, Xiangbing; Hu, Xingming; Qian, Qian; Fu, Xiangdong; Wang, Yonghong; Li, Jiayang

    2013-10-01

    Ideal plant architecture1 (IPA1) is critical in regulating rice (Oryza sativa) plant architecture and substantially enhances grain yield. To elucidate its molecular basis, we first confirmed IPA1 as a functional transcription activator and then identified 1067 and 2185 genes associated with IPA1 binding sites in shoot apices and young panicles, respectively, through chromatin immunoprecipitation sequencing assays. The Squamosa promoter binding protein-box direct binding core motif GTAC was highly enriched in IPA1 binding peaks; interestingly, a previously uncharacterized indirect binding motif TGGGCC/T was found to be significantly enriched through the interaction of IPA1 with proliferating cell nuclear antigen promoter binding factor1 or promoter binding factor2. Genome-wide expression profiling by RNA sequencing revealed IPA1 roles in diverse pathways. Moreover, our results demonstrated that IPA1 could directly bind to the promoter of rice teosinte branched1, a negative regulator of tiller bud outgrowth, to suppress rice tillering, and directly and positively regulate dense and erect panicle1, an important gene regulating panicle architecture, to influence plant height and panicle length. The elucidation of target genes of IPA1 genome-wide will contribute to understanding the molecular mechanisms underlying plant architecture and to facilitating the breeding of elite varieties with ideal plant architecture.

  4. Load-specific physical activity scores are related to tibia bone architecture.

    Science.gov (United States)

    Kindler, Joseph M; Ross, Hannah L; Laing, Emma M; Modlesky, Christopher M; Pollock, Norman K; Baile, Clifton A; Lewis, Richard D

    2015-04-01

    Assessment of physical activity in clinical bone studies is essential. Two bone-specific physical activity scoring methods, the Bone Loading History Questionnaire (BLHQ) and Bone-Specific Physical Activity Questionnaire (BPAQ), have shown correlations with bone density and geometry, but not architecture. The purpose of this study was to determine relationships between physical activity scoring methods and bone architecture in non-Hispanic white adolescent females (N = 24; 18-19 years of age). Bone loading scores (BLHQ [hip and spine] and past BPAQ) and energy expenditure (7-day physical activity recall) were determined from respective questionnaires. Estimates of trabecular and cortical bone architecture at the nondominant radius and tibia were assessed via magnetic resonance imaging. Total body and regional areal bone mineral density (aBMD), as well as total body fat mass and fat-free soft tissue (FFST) mass were assessed via dual energy X-ray absorptiometry. Pearson's correlations and partial correlations adjusting for height, total body fat mass, and FFST were performed. Hip BLHQ scores were correlated with midtibia cortical volume (r = .43; p = .03). Adjusted hip and spine BLHQ scores were correlated with all midtibia cortical measures (r = .50-0.58; p < .05) and distal radius apparent trabecular number (r = .46-0.53; p < .05). BPAQ scores were correlated with all midtibia cortical (r = .41-0.51; p < .05) and most aBMD (r = .47-0.53; p < .05) measures. Energy expenditure was inversely associated with femoral neck aBMD only after statistical adjustment (r = .49, p < .05). These data show that greater load-specific physical activity scores, but not energy expenditure, are indicative of greater midtibia cortical bone quality, thus supporting the utility of these instruments in musculoskeletal research.

  5. Antimicrobial activity of thin metallic silver flakes, waste products of a manufacturing process

    Institute of Scientific and Technical Information of China (English)

    Manuela Anzano; Alessandra Tosti; Marina Lasagni; Alfredo Campiglio; Demetrio Pitea; Elena Collina*

    2011-01-01

    The aim of the research was to develop new products and processes from a manufacturing waste from an Italian metallurgic company.The company produced thin silver metallic films and the production scraps were silver flakes.The possibility to use the silver flakes in water disinfection processes was studied.The antimicrobial activity of the flakes was investigated in batch using Escherichia coli as Gram-negative microorganism model.The flakes did not show any antimicrobial activity,so they were activated with two different processes:thermal activation in reducing atmosphere and chemical activation,obtaining,respectively,reduced flakes (RF) and chemical flakes (CF).The flakes,activated with either treatment,showed antimicrobial activity against E.coli.The kill rate was dependent on the type of activated flakes.The chemical flakes were more efficient than reduced flakes.The kill rate determined for 1 g of CF,1.0 ± 0.2min-1,was greater than the kill rate determined for 1 g of RF,0.069 + 0.004 min-1.This was confirmed also by the minimum inhibitory concentration values.It was demonstrated that the antimicrobial capability was dependent on flakes amount and on the type of aqueous medium.Furthermore,the flakes maintained their properties also when used a second time.Finally,the antimicrobial activities of flakes were tested in an effluent of a wastewater treatment plant where a variety of heterotrophic bacteria were present.

  6. Architectural Design Education: Designing a Library, Public Communication and Information Center in the Manufacturing Zone of Central Eskis, Ehir Turkey, a Case Study

    Science.gov (United States)

    Caglar, Nur; Uludag, Zeynep

    2006-01-01

    It is a fact that architectural design education has become the focus of an extremely complicated set of issues and conscientious debates. Therefore, to extend and challenge educational understanding in architecture it becomes crucial to exchange pedagogical practices. In this article, a specific theoretical approach and teaching methodology,…

  7. ACTIVITY-BASED COSTING IN THE MANUFACTURING SECTOR: A MANAGERIAL INSTRUMENT FOR DECISION-MAKING

    Directory of Open Access Journals (Sweden)

    Ioana D. BUFAN

    2014-04-01

    Full Text Available The aim of this paper is to emphasize the importance of using the activity-based costing (management system in the manufacturing sector. The utility of the ABC (ABM system concerns decisions taken at a strategic and operational level. In our country, few managers understand the need for such a system and many Romanian companies use only a traditional costing system or don’t use one at all. The paper also includes a case study which is a small example of using the ABC method in a Romanian manufacturing company. The study shows that the ABC/ABM system helps managers to properly manage indirect costs (by activities and understand the profitability of products, distribution channels and customers. Therefore, it offers a powerful instrument for decision-making. Although ABC is a new system of cost calculation that is absolutely necessary, in most cases the ABC method must be implemented in addition to the traditional costing systems, which are essential for the purposes of management accounting.

  8. Microbial diversity, dynamics and activity throughout manufacturing and ripening of Castelmagno PDO cheese.

    Science.gov (United States)

    Dolci, P; Alessandria, V; Rantsiou, K; Bertolino, M; Cocolin, L

    2010-09-30

    The diversity, dynamics and activity of Castelmagno PDO cheese microbiota were studied in three batches produced in a floor valley farm, in the Grana Valley (northwest Italy), during the wintertime. Samples of milk, curd and cheese (core and subsurface) at different ripening time were submitted to both culture-dependent and -independent analysis. In particular, DNA and RNA directly extracted from the matrices were studied by PCR-Denaturing gradient gel electrophoresis (DGGE) and reverse transcription (RT)-PCR-DGGE. Culture-dependent methods highlighted the initial dominance of a thermophilic streptococcal population with the species Streptococcus thermophilus and S. agalactiae. Then, mesophilic lactococci occurred among isolates during manufacturing, with Lactococcus lactis which was also well represented in the first month of Castelmagno PDO ripening. At this point and throughout the ripening, lactobacilli prevailed in cheese samples, represented from Lactobacillus plantarum and Lb. casei. Culture-independent analysis underlined the undoubted role of L. lactis, actively involved in both Castelmagno PDO manufacturing and ripening. Despite Lb. helveticus was never isolated on selective media, a DGGE band referred to this microorganism was detected, at RNA level, in samples from ripened cheeses. On the other hand, Lb. plantarum was widely isolated from the plates, among lactobacilli, but never detected by direct analysis. Due to the importance of microbiota in the sensory richness and properties of traditional cheeses, new information have been added, in this work, on microbial diversity of Castelmagno PDO cheese.

  9. Current information technology needs of small to medium sized apparel manufacturers and contractors

    Energy Technology Data Exchange (ETDEWEB)

    Wipple, C.; Vosti, E.

    1997-11-01

    This report documents recent efforts of the American Textile Partnership (AMTEX) Demand Activated Manufacturing Architecture (DAMA) Project to address needs that are characterized of small to medium sized apparel manufactures and contractors. Background on the AMTEX/DAMA project and objectives for this specific efforts are discussed.

  10. 事件驱动的面向云制造服务架构及其开源实现%Event-driven service-oriented architecture for cloud manufacturing and its implementation with open source tools

    Institute of Scientific and Technical Information of China (English)

    姚锡凡; 金鸿; 李彬; 张洁; 林颖; 周宏甫

    2013-01-01

    Internet-of-Things enabled Cloud Manufacturing faces the problems such as vertical collaboration between services via the Internet of Services, the horizontal collaboration between devices via the Internet of Things (IoT), and consequent Complex Event Processing (CEP) and Event-Driven Architecture (EDA). Therefore, Cloud Computing, CEP, Service-Oriented Architecture (SOA) and EDA were fused to propose Event-Driven SOA for Cloud Manufacturing (EDSOA4CM), and EDSOA4CM was implemented with open source tools. The proposed architecture was the extension of SOA for Cloud Manufacturing (SOA4CM), its service-oriented and event-driven functions were supported by the Enterprise Service Bus (ESB), and event pattern detection and event-driven business process were implemented via an event flow engine and a rule engine.%物联网使能的云制造面临在垂直方向上通过务联网协同各种服务、在水平方向上通过物联网协同各种设备以及由此引起的事件复杂处理和事件驱动架构问题.为此,融合云计算、复杂事件处理、面向服务架构与事件驱动架构,提出事件驱动的面向云制造服务架构,并用开源软件加以实现.该架构是面向云制造服务架构的延伸,能够通过企业服务总线实现面向服务与事件驱动功能,通过事件流引擎和规则引擎结合实现事件模式检测和事件驱动的业务流程.

  11. Analysis of Wooden Toy Manufacturing Costs Through the Application of a Time-Driven Activity-Based Costing System

    OpenAIRE

    PONGWASIT, Ramida; CHOMPU-INWAI, Rungchat

    2016-01-01

    The case study company, which manufactures wooden toys, encounters problems when fixing its product prices, since its experienced owners tend to dictate the prices of all the products, yet do not have available the appropriate product price and cost data. Currently, the company’s product costs are calculated using traditional accounting methods, but these are unable to accurately record the costs associated with the resources used and activities that occur during manufacture. Furthermore, whe...

  12. Architectural technology

    DEFF Research Database (Denmark)

    2005-01-01

    The booklet offers an overall introduction to the Institute of Architectural Technology and its projects and activities, and an invitation to the reader to contact the institute or the individual researcher for further information. The research, which takes place at the Institute of Architectural...... Technology at the Roayl Danish Academy of Fine Arts, School of Architecture, reflects a spread between strategic, goal-oriented pilot projects, commissioned by a ministry, a fund or a private company, and on the other hand projects which originate from strong personal interests and enthusiasm of individual...

  13. The history of the peat manufacturing industry in The Netherlands: Peat moss litter and active carbon

    Directory of Open Access Journals (Sweden)

    M.A.W. Gerding

    2015-11-01

    Full Text Available This article describes the development of three major forms of peat processing by the manufacturing industry in The Netherlands since the last quarter of the 19th century. At a time when peat as a fuel was gradually being replaced by coal, the first form was the peat moss litter industry. Peat moss litter was made from white peat that was ground and sieved in factories which were located mainly in bog areas in the south-east of the province of Drenthe. It served as excellent bedding for horses and cattle. The second form of industrial peat processing was the manufacture, from 1921 onwards, of active carbon made from black peat. The Purit (Norit factory, now part of the Cabot Corporation, is still the only active carbon factory using peat as a raw material. The third form of peat processing was the production of garden peat and potting soil. This is still a widespread activity in peat areas all over the world. The peat moss litter industry thrived from the 1880s until shortly after the First World War. The arrival of the horse-drawn tram in all of the major cities of Europe created a great demand for animal bedding to be used in the vast stables of the tramway companies. Peat moss litter was cleaner, healthier and easier to handle than straw. There was similar demand from the armies, which used millions of horses during the First World War. Owing to the development of motorised vehicles, the peat market collapsed after the war and this plunged the industry into a prolonged crisis which was not overcome until peat was found to be a suitable growing medium for horticulture in the 1950s. Living and working conditions in peatlands were harsh, earnings irregular and labourers’ rights limited. The peat manufacturing industry was the first to introduce collective labour agreements, medical benefits and pension plans. Nonetheless massive unemployment, poverty and the necessity to migrate to other parts of the country were clear signs that the era of

  14. Effects of Active Subsidence Vs. Existing Basin Geometry on Fluviodeltaic Channels and Stratal Architecture

    Science.gov (United States)

    Liang, M.; Kim, W.; Passalacqua, P.

    2015-12-01

    Tectonic subsidence and basin topography, both determining the accommodation, are fundamental controls on the basin filling processes. Their effects on the fluvial organization and the resultant subsurface patterns remain difficult to predict due to the lack of understanding about interaction between internal dynamics and external controls. Despite the intensive studies on tectonic steering effects on alluvial architecture, how the self-organization of deltaic channels, especially the distributary channel network, respond to tectonics and basin geometry is mostly unknown. Recently physical experiments and field studies have hinted dramatic differences in fluviodeltaic evolution between ones associated with active differential subsidence and existing basin depth. In this work we designed a series of numerical experiments using a reduced-complexity channel-resolving model for delta formation, and tested over a range of localized subsidence rates and topographic depression in basin geometry. We also used a set of robust delta metrics to analyze: i) shoreline planform asymmetry, ii) channel and lobe geometry, iii) channel network pattern, iv) autogenic timescales, and v) subsurface structure. The modeling results show that given a similar final thickness, active subsidence enhances channel branching with smaller channel sand bodies that are both laterally and vertically connected, whereas existing topographic depression causes more large-scale channel avulsions with larger channel sand bodies. In general, both subsidence and existing basin geometry could steer channels and/or lock channels in place but develop distinct channel patterns and thus stratal architecture.

  15. Product Architecture Definition: Evaluating the Potentiality of TRIZ Tools

    OpenAIRE

    Lorenzo, Fiorineschi; Frillici, Francesco Saverio; Rissone, Paolo; Cascini, Gaetano

    2015-01-01

    Product Architecture definition plays more and more a crucial role for enhancing product customizability, easing after-sale management and reducing manufacturing costs. Despite major efforts have been dedicated to the development of methods and tools supporting Product Architecture definition for “Adaptive Design” tasks, no real means are available while addressing more radical innovation activities. The paper proposes a critical overview of TRIZ models and tools to evaluate their potential i...

  16. Manufacturing and testing a thin glass mirror shell with piezoelectric active control

    Science.gov (United States)

    Spiga, D.; Barbera, M.; Collura, A.; Basso, S.; Candia, R.; Civitani, M.; Di Bella, M.; Di Cicca, G.; Lo Cicero, U.; Lullo, G.; Pelliciari, C.; Riva, M.; Salmaso, B.; Sciortino, L.; Varisco, S.

    2015-09-01

    Optics for future X-ray telescopes will be characterized by very large aperture and focal length, and will be made of lightweight materials like glass or silicon in order to keep the total mass within acceptable limits. Optical modules based on thin slumped glass foils are being developed at various institutes, aiming at improving the angular resolution to a few arcsec HEW. Thin mirrors are prone to deform, so they require a careful integration to avoid deformations and even correct forming errors. On the other hand, this offers the opportunity to actively correct the residual deformation: a viable possibility to improve the mirror figure is the application of piezoelectric actuators onto the non-optical side of the mirrors, and several groups are already at work on this approach. The concept we are developing consists of actively integrating thin glass foils with piezoelectric patches, fed by voltages driven by the feedback provided by X-rays. The actuators are commercial components, while the tension signals are carried by a printed circuit obtained by photolithography, and the driving electronic is a multi-channel low power consumption voltage supply developed inhouse. Finally, the shape detection and the consequent voltage signal to be provided to the piezoelectric array are determined in X-rays, in intra-focal setup at the XACT facility at INAF/OAPA. In this work, we describe the manufacturing steps to obtain a first active mirror prototype and the very first test performed in X-rays.

  17. Improving Polymerase Activity with Unnatural Substrates by Sampling Mutations in Homologous Protein Architectures.

    Science.gov (United States)

    Dunn, Matthew R; Otto, Carine; Fenton, Kathryn E; Chaput, John C

    2016-05-20

    The ability to synthesize and propagate genetic information encoded in the framework of xeno-nucleic acid (XNA) polymers would inform a wide range of topics from the origins of life to synthetic biology. While directed evolution has produced examples of engineered polymerases that can accept XNA substrates, these enzymes function with reduced activity relative to their natural counterparts. Here, we describe a biochemical strategy that enables the discovery of engineered polymerases with improved activity for a given unnatural polymerase function. Our approach involves identifying specificity determining residues (SDRs) that control polymerase activity, screening mutations at SDR positions in a model polymerase scaffold, and assaying key gain-of-function mutations in orthologous protein architectures. By transferring beneficial mutations between homologous protein structures, we show that new polymerases can be identified that function with superior activity relative to their starting donor scaffold. This concept, which we call scaffold sampling, was used to generate engineered DNA polymerases that can faithfully synthesize RNA and TNA (threose nucleic acid), respectively, on a DNA template with high primer-extension efficiency and low template sequence bias. We suggest that the ability to combine phenotypes from different donor and recipient scaffolds provides a new paradigm in polymerase engineering where natural structural diversity can be used to refine the catalytic activity of synthetic enzymes.

  18. Embedded Real-Time Architecture for Level-Set-Based Active Contours

    Directory of Open Access Journals (Sweden)

    Dejnožková Eva

    2005-01-01

    Full Text Available Methods described by partial differential equations have gained a considerable interest because of undoubtful advantages such as an easy mathematical description of the underlying physics phenomena, subpixel precision, isotropy, or direct extension to higher dimensions. Though their implementation within the level set framework offers other interesting advantages, their vast industrial deployment on embedded systems is slowed down by their considerable computational effort. This paper exploits the high parallelization potential of the operators from the level set framework and proposes a scalable, asynchronous, multiprocessor platform suitable for system-on-chip solutions. We concentrate on obtaining real-time execution capabilities. The performance is evaluated on a continuous watershed and an object-tracking application based on a simple gradient-based attraction force driving the active countour. The proposed architecture can be realized on commercially available FPGAs. It is built around general-purpose processor cores, and can run code developed with usual tools.

  19. Facile synthesis of dendritic gold nanostructures with hyperbranched architectures and their electrocatalytic activity toward ethanol oxidation.

    Science.gov (United States)

    Huang, Jianshe; Han, Xinyi; Wang, Dawei; Liu, Dong; You, Tianyan

    2013-09-25

    Gold dendritic nanostructures with hyperbranched architectures were synthesized by the galvanic replacement reaction between nickel wire and HAuCl4 in aqueous solution. The study revealed that the morphology of the obtained nanostructures strongly depended on experimental parameters such as the HAuCl4 solution concentration, reaction temperature, and time, as well as stirring or not. According to the investigation of the growth process, it was proposed that gold nanoparticles with rough surfaces were first deposited on the nickel substrate and that subsequent growth preferentially occurred on the preformed gold nanoparticles, finally leading to the formation of hyperbranched gold dendrites via a self-organization process under nonequilibrium conditions. The electrochemical experiment results demonstrated that the as-obtained gold dendrites exhibited high catalytic activity toward ethanol electrooxidation in alkaline solution, indicating that this nanomaterial may be a potential catalyst for direct ethanol fuel cells.

  20. Manufacturing an active X-ray mirror prototype in thin glass.

    Science.gov (United States)

    Spiga, D; Barbera, M; Collura, A; Basso, S; Candia, R; Civitani, M; Di Bella, M S; Di Cicca, G; Lo Cicero, U; Lullo, G; Pelliciari, C; Riva, M; Salmaso, B; Sciortino, L; Varisco, S

    2016-01-01

    Adjustable mirrors equipped with piezo actuators are commonly used at synchrotron and free-electron laser (FEL) beamlines, in order to optimize their focusing properties and sometimes to shape the intensity distribution of the focal spot with the desired profile. Unlike them, X-ray mirrors for astronomy are much thinner in order to enable nesting and reduce the areal mass, and the application of piezo actuators acting normally to the surface appears much more difficult. There remains the possibility to correct the deformations using thin patches that exert a tangential strain on the rear side of the mirror: some research groups are already at work on this approach. The technique reported here relies on actively integrating thin glass foils with commercial piezoceramic patches, fed by voltages driven by the feedback provided by X-rays, while the tension signals are carried by electrodes on the back of the mirror, obtained by photolithography. Finally, the shape detection and the consequent voltage signal to be provided to the piezoelectric array will be determined by X-ray illumination in an intra-focal setup at the XACT facility. In this work, the manufacturing steps for obtaining a first active mirror prototype are described.

  1. Architecture on Architecture

    DEFF Research Database (Denmark)

    Olesen, Karen

    2016-01-01

    This paper will discuss the challenges faced by architectural education today. It takes as its starting point the double commitment of any school of architecture: on the one hand the task of preserving the particular knowledge that belongs to the discipline of architecture, and on the other hand...... that is not scientific or academic but is more like a latent body of data that we find embedded in existing works of architecture. This information, it is argued, is not limited by the historical context of the work. It can be thought of as a virtual capacity – a reservoir of spatial configurations that can...... the autonomy of architecture, not as an esoteric concept but as a valid source of information in a pragmatic design practice, may help us overcome the often-proclaimed dichotomy between formal autonomy and a societally committed architecture. It follows that in architectural education there can be a close...

  2. Exposure characteristics of ferric oxide nanoparticles released during activities for manufacturing ferric oxide nanomaterials.

    Science.gov (United States)

    Xing, Mingluan; Zhang, Yuanbao; Zou, Hua; Quan, Changjian; Chang, Bing; Tang, Shichuan; Zhang, Meibian

    2015-02-01

    The exposure characteristics of Fe2O3 nanoparticles (NPs) released in a factory were investigated, as exposure data on this type of NP is absent. The nature of the particles was identified in terms of their concentrations [i.e. number concentration (NC(20-1000 nm)), mass concentration (MC(100-1000 nm)), surface area concentration (SAC(10-1000 nm))], size distribution, morphology and elemental composition. The relationships between different exposure metrics were determined through analyses of exposure ranking (ER), concentration ratios (CR), correlation coefficients and shapes of the particle concentration curves. Work activities such as powder screening, material feeding and packaging generated higher levels of NPs as compared to those of background particles (p modal size of the Fe2O3 NPs remained relatively constant (ranging from 10 to 15 nm) during the working periods. The ER, CR values and the shapes of NC(20-1000 nm) and SAC(10-1000 nm) curves were similar; however, these were significantly different from those for MC(100-1000 nm). There was a high correlation between NC(20-1000 nm) and SAC(10-1000 nm), and relatively lower correlations between the two and MC(100-1000 nm). These findings suggest that the work activities during the manufacturing processes generated high levels of primary Fe2O3 NPs. The particle concentrations exhibited periodicity and were activity dependent. The number and SACs were found to be much more relevant metrics for characterizing NPs than was the mass concentration.

  3. Magnet Architectures and Active Radiation Shielding Study - SR2S Workshop

    Science.gov (United States)

    Westover, Shane; Meinke, Rainer; Burger, William; Ilin, Andrew; Nerolich, Shaun; Washburn, Scott

    2014-01-01

    Analyze new coil configurations with maturing superconductor technology -Develop vehicle-level concept solutions and identify engineering challenges and risks -Shielding performance analysis Recent advances in superconducting magnet technology and manufacturing have opened the door for re-evaluating active shielding solutions as an alternative to mass prohibitive passive shielding.Publications on static magnetic field environments and its bio-effects were reviewed. Short-term exposure information is available suggesting long term exposure may be okay. Further research likely needed. center dotMagnetic field safety requirements exist for controlled work environments. The following effects have been noted with little noted adverse effects -Magnetohydrodynamic (MHD) effects on ionized fluids (e.g. blood) creating an aortic voltage change -MHD interaction elevates blood pressure (BP) center dot5 Tesla equates to 5% BP elevation -Prosthetic devises and pacemakers are an issue (access limit of 5 gauss).

  4. Active Vibration Isolation of Micro-Manufacturing Platform Based on Neural Network

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The micromation and precision of the Micro-Electromechanical System demand that its manufacturing, measuring and assembling must work in a micro-manufacturing platform with good ability to isolate vibrations. This paper develops a vibration isolation system of micro-manufacturing platform. The brains of many kinds of birds can isolate vibrations well, such as woodpecker's brain. When a woodpecker pecks the wood at the speed as 1.6 times as the velocity of sound, its brain will tolerate the wallop 1 500 time...

  5. A new architecture for printable photovoltaics overcoming conventional module limits.

    Science.gov (United States)

    Kang, Hongkyu; Hong, Soonil; Back, Hyungcheol; Lee, Kwanghee

    2014-03-12

    A new architecture for manufacturing large-area polymer solar cells that does not produce concomitant aperture and Ohmic losses is presented. By introducing the innovative concept of metal-filamentary nanoelectrodes, which are vertically formed inside the main active layers, loss-free, widely expandable solar cells with the highest relative power conversion efficiency (ca. 90%) in organic photovoltaic systems are demonstrated.

  6. System Architecture for a Military Weapon System Development Process to Integrate Design and the Manufacturing Process for Use by a Government Technical Development Agency

    Science.gov (United States)

    2014-09-01

    development process is utilized. The FDC process is similar to and based upon the “spiral –to-circle” model used by Industry and described by Maier and...it difficult to defend a claim that the new fuze design cannot be produced. This process is modeled after current product development practices used...it needs to be” (2007). 17 A significant part of CE is the concept of Design for Manufacturability (DFM), which is described by Chiang and Kawa

  7. Telemetric Study of Sleep Architecture and Sleep Homeostasis in the Day-Active Tree Shrew Tupaia belangeri

    NARCIS (Netherlands)

    Coolen, Alex; Hoffmann, Kerstin; Barf, R. Paulien; Fuchs, Eberhard; Meerlo, Peter

    2012-01-01

    Study Objectives: In this study the authors characterized sleep architecture and sleep homeostasis in the tree shrew, Tupaia belangeri, a small, omnivorous, day-active mammal that is closely related to primates. Design: Adult tree shrews were individually housed under a 12-hr light/12-hr dark cycle

  8. Architectural Illusion.

    Science.gov (United States)

    Doornek, Richard R.

    1990-01-01

    Presents a lesson plan developed around the work of architectural muralist Richard Haas. Discusses the significance of mural painting and gives key concepts for the lesson. Lists class activities for the elementary and secondary grades. Provides a photograph of the Haas mural on the Fountainbleau Hilton Hotel, 1986. (GG)

  9. Cytoplasmic streaming in Drosophila oocytes varies with kinesin activity and correlates with the microtubule cytoskeleton architecture.

    Science.gov (United States)

    Ganguly, Sujoy; Williams, Lucy S; Palacios, Isabel M; Goldstein, Raymond E

    2012-09-18

    Cells can localize molecules asymmetrically through the combined action of cytoplasmic streaming, which circulates their fluid contents, and specific anchoring mechanisms. Streaming also contributes to the distribution of nutrients and organelles such as chloroplasts in plants, the asymmetric position of the meiotic spindle in mammalian embryos, and the developmental potential of the zygote, yet little is known quantitatively about the relationship between streaming and the motor activity which drives it. Here we use Particle Image Velocimetry to quantify the statistical properties of Kinesin-dependent streaming during mid-oogenesis in Drosophila. We find that streaming can be used to detect subtle changes in Kinesin activity and that the flows reflect the architecture of the microtubule cytoskeleton. Furthermore, based on characterization of the rheology of the cytoplasm in vivo, we establish estimates of the number of Kinesins required to drive the observed streaming. Using this in vivo data as the basis of a model for transport, we suggest that the disordered character of transport at mid-oogenesis, as revealed by streaming, is an important component of the localization dynamics of the body plan determinant oskar mRNA.

  10. Assessment of microbial respiratory activity of a manufactured gas plant soil after remediation using sunflower oil.

    Science.gov (United States)

    Gong, Zongqiang; Alef, Kassem; Wilke, Berndt-Michael; Mai, Maike; Li, Peijun

    2005-09-30

    Microbial activity of a manufactured gas plant (MGP) soil, as well as remaining oil degradability, before and after remediation using sunflower oil was assessed. A sandy soil contaminated with polycyclic aromatic hydrocarbons (PAHs) was collected from an MGP site in Berlin, Germany. Column solubilizations of PAHs from the field-moist soil and air-dried soil using sunflower oil as an extractant at an oil/soil ratio of 2:1 (v/m) were carried out to compare PAH removals from the soil under these two conditions. After column solubilizations, portions of untreated soil (UTS), solubilized field-moist soil (SFMS), and solubilized air-dried soil (SADS) were amended with nutrients. Both nutrient amended and unamended soil samples were subjected to soil respiratory measurement. Soil respiration parameters, such as basal respiration rate, nutrient-induced respiration rate, lag time, exponential growth rate, respiratory activation quotient, peak maximum time, and cumulative CO2 evolution were calculated from the soil respiration curves. The parameters were compared using analysis of variance (ANOVA) and least-significance difference (LSD). Results showed that the impact of soil moisture on the PAH removals was quite significant, with the SADS showing higher PAH removals and the SFMS showing lower ones. There were significant differences between the respiration parameters with respect to the UTS, SFMS, and SADS. Basal respiration rate, nutrient-induced respiration rate, and exponential growth rate were lower for the SFMS and SADS relative to the UTS. Lag time and peak maximum time were higher for the SFMS and SADS relative to the UTS. Exponential growth rate was higher for the SFMS relative to the SADS. These parameters demonstrated that soil microbial activity was reduced at the onset of the test, because a lot of bioavailable materials for microbial growth were removed by sunflower oil. On the other hand, cumulative CO2 evolutions in the SFMS and SADS were higher than that in

  11. Architecture engineering toward highly active palladium integrated titanium dioxide yolk-double-shell nanoreactor for catalytic applications

    Science.gov (United States)

    Liu, Baocang; Wang, Qin; Yu, Shengli; Jing, Peng; Liu, Lixia; Xu, Guangran; Zhang, Jun

    2014-09-01

    Rational design of the hierarchical architecture of a material with well controlled functionality is crucially important for improving its properties. In this paper, we present the general strategies for rationally designing and constructing three types of hierarchical Pd integrated TiO2 double-shell architectures, i.e. yolk-double-shell TiO2 architecture (Pd@TiO2/Pd@TiO2) with yolk-type Pd nanoparticles residing inside the central cavity of the hollow TiO2 structure; ultrafine Pd nanoparticles homogenously dispersed on both the external and internal surfaces of the inner TiO2 shell; and double-shell TiO2 architecture (@TiO2/Pd@TiO2) with Pd nanoparticles solely loaded on the external surface of the inner TiO2 shell, and double-shell TiO2 architecture (@TiO2@Pd@TiO2) with Pd nanoparticles dispersed in the interlayer space of double TiO2 shells, via newly developed Pd2+ ion-diffusion and Pd sol impregnation methodologies. These architectures are well controlled in structure, size, morphology, and configuration with Pd nanoparticles existing in various locations. Owing to the variable synergistic effects arising from the location discrepancies of Pd nanoparticle in the architectures, they exhibit remarkable variations in catalytic activity. In particular, different from previously reported yolk-shell structures, the obtained yolk-double-shell Pd@TiO2/Pd@TiO2 architecture, which is revealed for the first time, possesses a uniform hierarchical structure, narrow size distribution, and good monodispersibility, and it creates two Pd-TiO2 interfaces on the external and internal surfaces of the inner TiO2 shell, leading to the strongest synergistic effect of Pd nanoparticles with TiO2 shell. Furthermore, the interlayer chamber between the double TiO2 shells connecting with the central cavity of the hollow TiO2 structure through the mesoporous TiO2 wall forms a nanoreactor for enriching the reactants and preventing the deletion of Pd nanoparticles during the reaction, thus

  12. Fundamentals of Digital Manufacturing Science

    CERN Document Server

    Zhou, Zude; Chen, Dejun

    2012-01-01

    The manufacturing industry will reap significant benefits from encouraging the development of digital manufacturing science and technology. Digital Manufacturing Science uses theorems, illustrations and tables to introduce the definition, theory architecture, main content, and key technologies of digital manufacturing science. Readers will be able to develop an in-depth understanding of the emergence and the development, the theoretical background, and the techniques and methods of digital manufacturing science. Furthermore, they will also be able to use the basic theories and key technologies described in Digital Manufacturing Science to solve practical engineering problems in modern manufacturing processes. Digital Manufacturing Science is aimed at advanced undergraduate and postgraduate students, academic researchers and researchers in the manufacturing industry. It allows readers to integrate the theories and technologies described with their own research works, and to propose new ideas and new methods to...

  13. 基于关键性能指标的流程行业制造执行系统评价体系%Evaluation architecture of manufacturing execution system based on key performance indicators in process industry

    Institute of Scientific and Technical Information of China (English)

    朱理; 苏宏业; 沈清泓

    2012-01-01

    面向流程行业,根据制造执行系统的具体特点引人关键性能指标,提出了流程行业制造执行系统的关键性能指标概念定义和评价体系,从流程行业中的生产、质量、库存、维护和能源五大运行部分给出了相应的规范化关键性能指标。通过该评估体系用于实际指导石化行业能源消耗的应用实例,实现了对流程行业综合能耗的有效评估。%According to the characteristics of Manufacturing Execution System (MES) in process industry, the concept and evaluation architecture of Key Performance Indicators (KPI) for MES were studied. The corresponding and normalized KPIs were given from the main operation aspects of production, quality, inventory, maintenance and energy in process industry. The evaluation architecture was applied to guide the energy consumption in petrochemical industry, and the effective evaluation for comprehensive energy consumption of process industry was realized.

  14. Strategic Roles of Manufacturing

    DEFF Research Database (Denmark)

    Yang, Cheng

    Addressing three development trends of manufacturing, this thesis aims to explore: (1) facing challenges on manufacturing (globalisation, knowledge-based manufacturing and servitisation of manufacturing), what kinds of roles does manufacturing play within industrial companies; (2) along...... with the trend of globalisation, how do industrial companies develop their global manufacturing networks? These two questions are actually interlinked. On the one hand, facing increasing offshoring and outsourcing of production activities, industrial companies have to understand how to develop their global...... manufacturing networks. On the other hand, ongoing globalisation also brings tremendous impacts to post-industrial economies (e.g. Denmark). A dilemma therefore arises, i.e. whether it is still necessary to keep manufacturing in these post-industrial economies; if yes, what kinds of roles manufacturing should...

  15. On the beginnings of cinema historiography: the architecture of a modern commercial activity

    Directory of Open Access Journals (Sweden)

    Andrés Ávila Gómez

    2015-12-01

    Full Text Available This article outlines a structured critical reflection of Ben Hall´s analysis in his The Best Remaining Seats. The Golden Age of the Movie Palace. When it was published in 1961, this article progressively provoked interest in commercial architecture. Its mutations foretold its own disappearance, in the ways that were known at that time: it was architecture for cinematographic exhibition. Beginning with the identification of the main historic elements that are suggested by Hall, this analysis seeks to establish some of the continuities or lack of continuities that they subsequently have in renowned researchers’ written works on the ever-changing cinema architecture.

  16. Manufacturing in Denmark

    DEFF Research Database (Denmark)

    Hansen, Johannes; Boer, Henrike Engele Elisabeth; Boer, Harry

    This report compares the manufacturing strategies, practices, performances and improvement activities of 39 companies that are representative for the Danish assembly industry with those of 804 companies from 19 other countries. The data supporting this report were collected in 2013 and concern......: • Manufacturing strategies pursued and implemented between 2010 and 2012. • Performance improvements achieved during that period. • Actual manufacturing practices and performances as well as competitive priorities in 2012. • Manufacturing strategies pursued for the years 2010-2012....

  17. Late Quaternary activity along the Ferrara thrust inferred from stratigraphic architecture and geophysical surveys

    Science.gov (United States)

    Stefani, Marco; Bignardi, Samuel; Caputo, Riccardo; Minarelli, Luca; Abu-Zeid, Nasser; Santarato, Giovanni

    2010-05-01

    Since Late Miocene, the Emilia-Romagna portion of the Po Plain-Adriatic foredeep basin was progressively affected by compressional deformation, due to the northward propagation of the Apennines fold-and-thrust belt. The major tectonic structures within the basin have been recognised and are relatively well known, thanks to the widespread, even if outdated, seismic survey, performed after WW II, for hydrocarbon exploration. More recently, a large amount of surface and shallow-subsurface information has been provided by the CARG geological mapping project. The region therefore provides a valuable opportunity to discuss the genetic relationship between tectonic deformation, eustatic-paleoclimatic fluctuations, and depositional architecture. The activity of blind thrusts and fault-propagation folds induced repeated angular unconformities and impressive lateral variations in the Pliocene-Quaternary stratigraphy, causing thickness changes, from a few metres, close to the Apennines piedmont line, to more than 9 km, in fast subsiding depocenters (e.g. Lido di Savio). In the Ferrara region, the post-Miocene succession ranges from about 4 km, west of Sant'Agostino, to less than 200 m, on the Casaglia anticline, where Late Quaternary fluvial strata rest on Miocene marine marls, with an angular unconformity relationship. In this sector of the Po Plain, the tip-line of the northernmost thrust has been reconstructed north of the Po River (Occhiobello) and is associated with the growth of a large fold (Ferrara-Casaglia anticline), cross-cut by a complex splay of minor backthrusts and reverse faults. The thrust-anticline structure hosts an energy producing geothermal field, whose hydrogeological behaviour is largely influenced by the fracture pattern. The Apennines frontal thrust probably provided the seismic source for the earthquakes that severely damaged Ferrara, during the 1570 a.D. fall season, as documented by the structural damage still visible in many historic buildings (e

  18. Implementation of activity-based costing (ABC) to drive cost reduction efforts in a semiconductor manufacturing operation

    Science.gov (United States)

    Naguib, Hussein; Bol, Igor I.; Lora, J.; Chowdhry, R.

    1994-09-01

    This paper presents a case study on the implementation of ABC to calculate the cost per wafer and to drive cost reduction efforts for a new IC product line. The cost reduction activities were conducted through the efforts of 11 cross-functional teams which included members of the finance, purchasing, technology development, process engineering, equipment engineering, production control, and facility groups. The activities of these cross functional teams were coordinated by a cost council. It will be shown that these activities have resulted in a 57% reduction in the wafer manufacturing cost of the new product line. Factors contributed to successful implementation of an ABC management system are discussed.

  19. Detail in architecture: Between arts

    Directory of Open Access Journals (Sweden)

    Dulencin Juraj

    2016-06-01

    Full Text Available Architectural detail represents an important part of architecture. Not only can it be used as an identifier of a specific building but at the same time enhances the experience of the realized project. Within it lie the signs of a great architect and clues to understanding his or her way of thinking. It is therefore the central topic of a seminar offered to architecture students at the Brno University of Technology. During the course of the semester-long class the students acquaint themselves with atypical architectural details of domestic and international architects by learning to read them, understand them and subsequently draw them by creating architectural blueprints. In other words, by general analysis of a detail the students learn theoretical thinking of its architect who, depending on the nature of the design, had to incorporate a variety of techniques and crafts. Students apply this analytical part to their own architectural detail design. The methodology of the seminar consists of experiential learning by project management and is complemented by a series of lectures discussing a diversity of details as well as materials and technologies required to implement it. The architectural detail design is also part of students’ bachelors thesis, therefore, the realistic nature of their blueprints can be verified in the production process of its physical counterpart. Based on their own documentation the students choose the most suitable manufacturing process whether it is supplied by a specific technology or a craftsman. Students actively participate in the production and correct their design proposals in real scale with the actual material. A student, as a future architect, stands somewhere between a client and an artisan, materializes his or her idea and adjusts the manufacturing process so that the final detail fulfills aesthetic consistency and is in harmony with its initial concept. One of the very important aspects of the design is its

  20. Implementation of a Cellular Manufacturing Tool for Minimization of Non Value Added Activities

    Directory of Open Access Journals (Sweden)

    Amanparteek Singh

    2014-08-01

    Full Text Available The purpose of this study is to develop a plan for reducing lead-times and increasing profit of Centre bolt product by using value stream mapping. The Centre bolt product manufacturer is inefficient because it produces products in large batch quantities and has poor product flow as operations being departmentalized and departments are very far away from each other due to this increase in lead-times could cause a loss in the market share to its competitors. The Centre bolt product manufacturer must reduce its lead-times in order to remain competitive and continue its growth by providing quality products in a timely manner. A study will be carried out using value stream mapping to determine areas of potential improvement on the plant floor. A current state map will be developed and analyzed the areas that have potential for improvement. A future state map will then be created to suggest ways to reduce lead-times and increase profit. The map will include lean manufacturing methods to reduce wastes in the system; increasing profit and reducing lead-times. Current state and future state of manufacturing of a firm are compared and witnessed: 50 percent reduction in lead time, 4 percent reduction in processing time, 58.5 percent reduction in WIP and 22 percent reduction in manpower required to perform same amount of work.

  1. Green Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Patten, John

    2013-12-31

    Green Manufacturing Initiative (GMI): The initiative provides a conduit between the university and industry to facilitate cooperative research programs of mutual interest to support green (sustainable) goals and efforts. In addition to the operational savings that greener practices can bring, emerging market demands and governmental regulations are making the move to sustainable manufacturing a necessity for success. The funding supports collaborative activities among universities such as the University of Michigan, Michigan State University and Purdue University and among 40 companies to enhance economic and workforce development and provide the potential of technology transfer. WMU participants in the GMI activities included 20 faculty, over 25 students and many staff from across the College of Engineering and Applied Sciences; the College of Arts and Sciences' departments of Chemistry, Physics, Biology and Geology; the College of Business; the Environmental Research Institute; and the Environmental Studies Program. Many outside organizations also contribute to the GMI's success, including Southwest Michigan First; The Right Place of Grand Rapids, MI; Michigan Department of Environmental Quality; the Michigan Department of Energy, Labor and Economic Growth; and the Michigan Manufacturers Technical Center.

  2. Architecture on Architecture

    DEFF Research Database (Denmark)

    Olesen, Karen

    2016-01-01

    that is not scientific or academic but is more like a latent body of data that we find embedded in existing works of architecture. This information, it is argued, is not limited by the historical context of the work. It can be thought of as a virtual capacity – a reservoir of spatial configurations that can...... the obligation to prepare students to perform in a profession that is largely defined by forces outside that discipline. It will be proposed that the autonomy of architecture can be understood as a unique kind of information: as architecture’s self-reliance or knowledge-about itself. A knowledge...... be transformed and reapplied endlessly through its confrontation with shifting information from outside the realms of architecture. A selection of architects’ statements on their own work will be used to demonstrate how in quite diverse contemporary practices the re-use of existing architectures is applied...

  3. Comparative Study of Alkali-Activated Fly Ash Manufactured Under Pulsed Microwave Curing and Thermal Oven Curing

    OpenAIRE

    Shi, Shi; Bai, Yun; Li, H.; Xu, D. L.; Basheer, P. A. Muhammed

    2014-01-01

    This paper compares the alkali-activated fly ash (AAFA) manufactured with thermal oven curing and pulsed microwave curing methods. Fly ash activated by 8M NaOH solution at a liquid to solid ratio of 0.3 was cured by thermal oven at 85°C and domestic microwave oven, respectively. Apart from compressive strength test, the temperature profiles of AAFA samples were captured by thermal camera. Reaction products of AAFA were characterised with XRD, FTIR and TG/DTG, while the microstructure of AAFA ...

  4. The global decentralization of commercial aircraft production: Implications for United States-based manufacturing activity

    Science.gov (United States)

    Pritchard, David John

    This research explores the role of industrial offset agreements and international subcontracting patterns in the global decentralization of US commercial aircraft production. Particular attention is given to the manufacturing processes involved in the design and assembly of large passenger jets (100 seats or more). It is argued that the current geography of aircraft production at the global level has been shaped by a new international distribution of input costs and technological capability. Specifically, low-cost producers within several of the newly emerging markets (NEMs) have acquired front-end manufacturing expertise as a direct result of industrial offset contracts and/or other forms of technology transfer (e.g. international joint-ventures, imports of advanced machine tools). The economic and technological implications of industrial offset (compensatory trade) are examined with reference to the commercial future of US aircraft production. Evidence gathered via personal interviews with both US and foreign producers suggests that the current Western duopoly (Boeing and Airbus) faces a rather uncertain future. In particular, the dissertation shows that the growth of subcontracting and industrial offset portends the transformation of Boeing from an aircraft manufacturer to a systems integrator. The economic implications of this potential reconfiguration of the US aircraft industry are discussed in the context of several techno-market futures, some of which look rather bleak for US workers in this industry.

  5. Manufacturing and thermomechanical testing of actively cooled all beryllium high heat flux test pieces

    Energy Technology Data Exchange (ETDEWEB)

    Vasiliev, N.N.; Sokolov, Yu.A.; Shatalov, G.E. [and others

    1995-09-01

    One of the problems affiliated to ITER high heat flux elements development is a problem of interface of beryllium protection with heat sink routinely made of copper alloys. To get rid of this problem all beryllium elements could be used as heat receivers in places of enhanced thermal loads. In accordance with this objectives four beryllium test pieces of two types have been manufactured in {open_quotes}Institute of Beryllium{close_quotes} for succeeding thermomechanical testing. Two of them were manufactured in accordance with JET team design; they are round {open_quotes}hypervapotron type{close_quotes} test pieces. Another two ones are rectangular test sections with a twisted tape installed inside of the circular channel. Preliminary stress-strain analysis have been performed for both type of the test pieces. Hypervapotrons have been shipped to JET where they were tested on JET test bed. Thermomechanical testing of pieces of the type of {open_quotes}swirl tape inside of tube{close_quotes} have been performed on Kurchatov Institute test bed. Chosen beryllium grade properties, some details of manufacturing, results of preliminary stress-strain analysis and thermomechanical testing of the test pieces {open_quotes}swirl tape inside of tube{close_quotes} type are given in this report.

  6. Lean Manufacturing measurement: The relationships between Lean activities and Lean metrics

    Directory of Open Access Journals (Sweden)

    Diego Fernando Manotas Duque

    2007-01-01

    Full Text Available Medición en Lean Manufacturing: Relaciones entre Actividades Lean y Métricas Lean Lean Manufacturing fue desarrollada por Toyota para satisfacer sus necesidades específicas en un mercado restringido y en tiempos de estrechez económica. Estos conceptos han sido estudiados y se ha comprobado su aplicabilidad en una amplia variedad de industrias. El objetivo de este artículo es el de integrar un conjunto de métricas que han sido propuestas por diferentes autores, de tal manera que sean consistentes con las etapas y elementos de implementaciones de Lean Manufacturing. Para lograrlo se presentan dos marcos de referencia para implementaciones Lean y los principales factores de éxito se utilizan como base para proponer métricas que identifiquen el avance en estos factores. Posteriormente se propone una tabla que cruza el impacto de las “Actividades Lean” sobre las métricas, postulando que muchos de los supuestos a priori sobre estos impactos deberían ser precisos. Finalmente se proponen algunas ideas para proyectos de investigación hacia el futuro y posibles extensiones de las aplicaciones propuestas aquí.

  7. Advanced optical manufacturing digital integrated system

    Science.gov (United States)

    Tao, Yizheng; Li, Xinglan; Li, Wei; Tang, Dingyong

    2012-10-01

    It is necessarily to adapt development of advanced optical manufacturing technology with modern science technology development. To solved these problems which low of ration, ratio of finished product, repetition, consistent in big size and high precision in advanced optical component manufacturing. Applied business driven and method of Rational Unified Process, this paper has researched advanced optical manufacturing process flow, requirement of Advanced Optical Manufacturing integrated System, and put forward architecture and key technology of it. Designed Optical component core and Manufacturing process driven of Advanced Optical Manufacturing Digital Integrated System. the result displayed effective well, realized dynamic planning Manufacturing process, information integration improved ratio of production manufactory.

  8. Kosmos = architecture

    Directory of Open Access Journals (Sweden)

    Tine Kurent

    1985-12-01

    Full Text Available The old Greek word "kosmos" means not only "cosmos", but also "the beautiful order", "the way of building", "building", "scenography", "mankind", and, in the time of the New Testament, also "pagans". The word "arhitekton", meaning first the "master of theatrical scenography", acquired the meaning of "builder", when the words "kosmos" and ~kosmetes" became pejorative. The fear that architecture was not considered one of the arts before Renaissance, since none of the Muses supervised the art of building, results from the misunderstanding of the word "kosmos". Urania was the Goddes of the activity implied in the verb "kosmein", meaning "to put in the beautiful order" - everything, from the universe to the man-made space, i. e. the architecture.

  9. Additive Manufacturing (AM) Activities and Non-Destructive Evaluation (NDE) at GSFC

    Science.gov (United States)

    Jones, Justin S.

    2017-01-01

    NASA personnel will be meeting with a delegation from the Japan Aerospace Exploration Agency (JAXA) Office of Safety and Mission Assurance (OSMA) at Langley Research Center on 2217 through 3217. The purpose of the meeting is a technical interchange between NASA and JAXA to discuss Non-Destructive Evaluation (NDE) of Additive Manufacturing (AM) parts and the HALT process (relates to accelerated life testing). The visitors will be a small group of Japanese citizens. Goddard Space Flight Center (GSFC) has been asked to participate in the meeting, either in person or via teleconference. This presentation covers NDE efforts at GSFC and provides a cursory overview of AM and lab capabilities.

  10. Special equipment in competitive activities of powerlifters and dynamics of its manufacture

    Directory of Open Access Journals (Sweden)

    Kotendzhy L. V.

    2012-02-01

    Full Text Available There was reviewed the problem of use of ergogenic facilities in powerlifting, which makes it possible to expand representation about patterns of this kind of sport development. There was given comparative characteristic of applying special equipment of alternative international powerlifting organizations. There was researched the influence of special equipment on the effectiveness of powerlifters. There was studied the chronology of manufacture dynamics of special powerlifting equipment in different periods. There was grounded the necessity of changes in priorities for further understanding of the special powerlifting equipment taking into account aesthetic, social and ethical norms and its impact on the human body.

  11. Process understanding for scale-up and manufacture of active ingredients

    CERN Document Server

    Houson, Ian

    2011-01-01

    Process Understanding is the underpinning knowledge that allows the manufacture of chemical entities to be carried out routinely, robustly and to the required standard of quality. This area has gained in importance over the last few years, particularly due to the recent impetus from the USA`s Food and Drug Administration. This book covers the multidisciplinary aspects required for successful process design, safety, modeling, scale-up, PAT, pilot plant implementation, plant design as well the rapidly expanding area of outsourcing. In discussing what process understanding means to differ

  12. Architectural slicing

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak; Hansen, Klaus Marius

    2013-01-01

    a system and a slicing criterion, architectural slicing produces an architectural prototype that contain the elements in the architecture that are dependent on the ele- ments in the slicing criterion. Furthermore, we present an initial design and implementation of an architectural slicer for Java.......Architectural prototyping is a widely used practice, con- cerned with taking architectural decisions through experiments with light- weight implementations. However, many architectural decisions are only taken when systems are already (partially) implemented. This is prob- lematic in the context...... of architectural prototyping since experiments with full systems are complex and expensive and thus architectural learn- ing is hindered. In this paper, we propose a novel technique for harvest- ing architectural prototypes from existing systems, \\architectural slic- ing", based on dynamic program slicing. Given...

  13. Architecture of the Product State Model Environment

    DEFF Research Database (Denmark)

    Holm Larsen, Michael; Lynggaard, Hans Jørgen B.

    2003-01-01

    technologies already haveproved their worth in the design and engineering phases of shipbuilding and in the operation phase.However, the handling of product information on the shop floor is not yet equally developed.The paper reports from the Brite-Euram project (No. BE97-4510) QualiGlobe focusing...... on thedevelopment activities of the PSM architecture. An example discusses how to handle product relatedinformation on the shop floor in a manufacturing company and focuses on how dynamically updatedproduct data can improve control of production activities. This prototype example of welding a jointbetween two steel...

  14. Modeling of Agile Intelligent Manufacturing-oriented Production Scheduling System

    Institute of Scientific and Technical Information of China (English)

    Zhong-Qi Sheng; Chang-Ping Tang; Ci-Xing Lv

    2010-01-01

    Agile intelligent manufacturing is one of the new manufacturing paradigms that adapt to the fierce globalizing market competition and meet the survival needs of the enterprises, in which the management and control of the production system have surpassed the scope of individual enterprise and embodied some new features including complexity, dynamicity, distributivity, and compatibility. The agile intelligent manufacturing paradigm calls for a production scheduling system that can support the cooperation among various production sectors, the distribution of various resources to achieve rational organization, scheduling and management of production activities. This paper uses multi-agents technology to build an agile intelligent manufacturing-oriented production scheduling system. Using the hybrid modeling method, the resources and functions of production system are encapsulated, and the agent-based production system model is established. A production scheduling-oriented multi-agents architecture is constructed and a multi-agents reference model is given in this paper.

  15. Supercritical fluid chromatography for GMP analysis in support of pharmaceutical development and manufacturing activities.

    Science.gov (United States)

    Hicks, Michael B; Regalado, Erik L; Tan, Feng; Gong, Xiaoyi; Welch, Christopher J

    2016-01-05

    Supercritical fluid chromatography (SFC) has long been a preferred method for enantiopurity analysis in support of pharmaceutical discovery and development, but implementation of the technique in regulated GMP laboratories has been somewhat slow, owing to limitations in instrument sensitivity, reproducibility, accuracy and robustness. In recent years, commercialization of next generation analytical SFC instrumentation has addressed previous shortcomings, making the technique better suited for GMP analysis. In this study we investigate the use of modern SFC for enantiopurity analysis of several pharmaceutical intermediates and compare the results with the conventional HPLC approaches historically used for analysis in a GMP setting. The findings clearly illustrate that modern SFC now exhibits improved precision, reproducibility, accuracy and robustness; also providing superior resolution and peak capacity compared to HPLC. Based on these findings, the use of modern chiral SFC is recommended for GMP studies of stereochemistry in pharmaceutical development and manufacturing.

  16. Architectural Considerations for Holonic Shop Floor Control

    DEFF Research Database (Denmark)

    Langer, Gilad; Bilberg, Arne

    1997-01-01

    as flexible. This is a highly de-manding task for the manufacturing control system. The emerging theory regarding Holonic Manufacturing Sys-tems (HMS) introduces an advantageous theoretical foundation for the control system of the manufacturing system of the future. This article presents an overview...... will present a model of both a holonic cell and multi-cell control architecture. The work is based on a theoretical study of new manufac-turing systems theories, practical test, development of a prototype, and two case studies. It is part of a research project which aims at developing a multi-cell control...... architecture based on the Holonic Manufacturing Sys-tem theory....

  17. Additive manufactured polymeric 3D scaffolds with tailored surface topography influence mesenchymal stromal cells activity.

    Science.gov (United States)

    Neves, Sara C; Mota, Carlos; Longoni, Alessia; Barrias, Cristina C; Granja, Pedro L; Moroni, Lorenzo

    2016-05-24

    Additive manufactured three-dimensional (3D) scaffolds with tailored surface topography constitute a clear advantage in tissue regeneration strategies to steer cell behavior. 3D fibrous scaffolds of poly(ethylene oxide terephthalate)/poly(butylene terephthalate) block copolymer presenting different fiber surface features were successfully fabricated by additive manufacturing combined with wet-spinning, in a single step, without any post-processing. The optimization of the processing parameters, mainly driven by different solvent/non-solvent combinations, led to four distinct scaffold types, with average surface roughness values ranging from 0.071 ± 0.012 μm to 1.950 ± 0.553 μm, average pore sizes in the x- and y-axis between 351.1 ± 33.6 μm and 396.1 ± 32.3 μm, in the z-axis between 36.5 ± 5.3 μm and 70.7 ± 8.8 μm, average fiber diameters between 69.4 ± 6.1 μm and 99.0 ± 9.4 μm, and porosity values ranging from 60.2 ± 0.8% to 71.7 ± 2.6%. Human mesenchymal stromal cells (hMSCs) cultured on these scaffolds adhered, proliferated, and produced endogenous extracellular matrix. The effect of surface roughness and topography on hMSCs differentiation was more evident for cells seeded at lower density, where the percentage of cells in direct contact with the surface was higher compared to more densely seeded scaffolds. Under osteogenic conditions, lower surface roughness values (0.227 ± 0.035 μm) had a synergistic effect on hMSCs behavior, while chondrogenesis was favored on rougher surfaces (1.950 ± 0.553 μm).

  18. Manufacturing plant control challenges and issues

    OpenAIRE

    Morel, Gérard; Valckenaers, Paul; Faure, Jean-Marc; Pereira, Carlos Eduardo; Diedrich, Christian

    2007-01-01

    International audience; Enterprise control system integration between business systems, manufacturing execution systems and shop-floor process-control systems remains a key issue for facilitating the deployment of plant-wide information control systems for practical e-business-to-manufacturing industry-led issues. Achievement of the integration-in-manufacturing paradigm based on centralized/distributed hardware/software automation architectures is evolving using the intelligence-in-manufactur...

  19. Architectural Prototyping

    DEFF Research Database (Denmark)

    Bardram, Jakob; Christensen, Henrik Bærbak; Hansen, Klaus Marius

    2004-01-01

    A major part of software architecture design is learning how specific architectural designs balance the concerns of stakeholders. We explore the notion of "architectural prototypes", correspondingly architectural prototyping, as a means of using executable prototypes to investigate stakeholders......' concerns with respect to a system under development. An architectural prototype is primarily a learning and communication vehicle used to explore and experiment with alternative architectural styles, features, and patterns in order to balance different architectural qualities. The use of architectural...... prototypes in the development process is discussed, and we argue that such prototypes can play a role throughout the entire process. The use of architectural prototypes is illustrated by three distinct cases of creating software systems. We argue that architectural prototyping can provide key insights...

  20. Architectural prototyping

    DEFF Research Database (Denmark)

    Bardram, Jakob Eyvind; Christensen, Henrik Bærbak; Hansen, Klaus Marius

    2004-01-01

    A major part of software architecture design is learning how specific architectural designs balance the concerns of stakeholders. We explore the notion of "architectural prototypes", correspondingly architectural prototyping, as a means of using executable prototypes to investigate stakeholders......' concerns with respect to a system under development. An architectural prototype is primarily a learning and communication vehicle used to explore and experiment with alternative architectural styles, features, and patterns in order to balance different architectural qualities. The use of architectural...... prototypes in the development process is discussed, and we argue that such prototypes can play a role throughout the entire process. The use of architectural prototypes is illustrated by three distinct cases of creating software systems. We argue that architectural prototyping can provide key insights...

  1. Computational manufacturing

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    This paper presents a general framework for computational manufacturing. The methodology of computational manufacturing aims at integrating computational geometry, machining principle, sensor information fusion, optimization, computational intelligence and virtual prototyping to solve problems of the modeling, reasoning, control, planning and scheduling of manufacturing processes and systems. There are three typical problems in computational manufacturing, i.e., scheduling (time-domain), geometric reasoning (space-domain) and decision- making (interaction between time-domain and space-domain). Some theoretical fundamentals of computational manufacturing are also discussed.

  2. Antimicrobial activity of tea as affected by the degree of fermentation and manufacturing season.

    Science.gov (United States)

    Chou, C C; Lin, L L; Chung, K T

    1999-05-01

    Bacillus subtilis, Escherichia coli, Proteus vulgaris, Pseudomonas fluorescens, Salmonella sp. and Staphylococcus aureus were used to test the antimicrobial activity of tea flush extract and extracts of various tea products. Among the six test organisms, P. fluorescens was the most sensitive to the extracts, while B. subtilis was the least sensitive. In general, antimicrobial activity decreased when the extents of tea fermentation increased. The antimicrobial activities of tea flush extract and extracts of tea products with different extents of fermentation varied with test organisms. Tea flush and Green tea, the unfermented tea, exerted the strongest antimicrobial activity followed by the partially fermented tea products such as Longjing, Tieh-Kuan-Ying, Paochung, and Oolong teas. On the other hand, Black tea, the completely fermented tea, showed the least antimicrobial activity. It was also noted that extracts of Oolong tea prepared in summer exhibited the strongest antimicrobial activity, followed by those prepared in spring, winter and fall.

  3. Precision manufacturing

    CERN Document Server

    Dornfeld, David

    2008-01-01

    Today there is a high demand for high-precision products. The manufacturing processes are now highly sophisticated and derive from a specialized genre called precision engineering. Precision Manufacturing provides an introduction to precision engineering and manufacturing with an emphasis on the design and performance of precision machines and machine tools, metrology, tooling elements, machine structures, sources of error, precision machining processes and precision process planning. As well as discussing the critical role precision machine design for manufacturing has had in technological developments over the last few hundred years. In addition, the influence of sustainable manufacturing requirements in precision processes is introduced. Drawing upon years of practical experience and using numerous examples and illustrative applications, David Dornfeld and Dae-Eun Lee cover precision manufacturing as it applies to: The importance of measurement and metrology in the context of Precision Manufacturing. Th...

  4. Appraising manufacturing location

    NARCIS (Netherlands)

    Steenhuis, Harm-Jan; Bruijn, de Erik J.

    2002-01-01

    International location of manufacturing activities is an issue for managers of manufacturing companies as well as public policy makers. For managers, the issue is relevant because international locations offer opportunities for lowering costs due to productivity improvements. For governments the iss

  5. Assessing manufacturing location

    NARCIS (Netherlands)

    Steenhuis, Harm-Jan; Bruijn, de Erik J.

    2004-01-01

    International location of manufacturing activities is an issue for managers of manufacturing companies as well as public policy-makers. For managers, the issue is relevant because international locations offer opportunities for lowering costs due to productivity improvements. For governments the iss

  6. Software Architecture of Manufacturing Execution Systems

    Directory of Open Access Journals (Sweden)

    Heiko Meyer

    2010-04-01

    Full Text Available The globalization of the economy and the associated factors of increasing effectiveness in production, shortening innovation cycles, safeguarding high quality, etc. are continually augmenting the pressure on the production business. It has been possible to compensate somewhat for this pressure in recent years by relocating production to low-cost countries. However, in the medium term, the demands of workers in countries that are now still low cost will increase, and production costs will rise as a result, so the need for action will arise. Tools will be needed to increase efficiency in existing production processes. It also must be considered that production in high-cost countries definitely has its advantages, so these countries are becoming more and more feasible as production locations and will remain so in the long term. The degree of automation is already extremely high in these countries, so modifying production processes will not increase efficiency significantly.

  7. Robotic Architectures

    Directory of Open Access Journals (Sweden)

    Mbali Mtshali

    2010-01-01

    Full Text Available In the development of mobile robotic systems, a robotic architecture plays a crucial role in interconnecting all the sub-systems and controlling the system. The design of robotic architectures for mobile autonomous robots is a challenging and complex task. With a number of existing architectures and tools to choose from, a review of the existing robotic architecture is essential. This paper surveys the different paradigms in robotic architectures. A classification of the existing robotic architectures and comparison of different proposals attributes and properties have been carried out. The paper also provides a view on the current state of designing robot architectures. It also proposes a conceptual model of a generalised robotic architecture for mobile autonomous robots.Defence Science Journal, 2010, 60(1, pp.15-22, DOI:http://dx.doi.org/10.14429/dsj.60.96

  8. Multi-agent Based Modeling of Manufacturing Network

    Institute of Scientific and Technical Information of China (English)

    GUO Yuming; SUN Yanming; ZHENG Shixiong

    2006-01-01

    An intelligent manufacturing system is modeled currently from the viewpoint of manufacturing applications, and the network platform's influence to manufacturing applications is not considered adequately. However any bottleneck in service oriented architecture (SOA) for the manufacturing network can affect the agility of the IT environment. In this paper, to achieve a trade-off between manufacturing resources and network resources, the manufacturing network is modeled with multi-agent, in which two kinds of basic elements, the manufacturing application unit and the network carrier of manufacturing information, are presented. And their main characters are described by colored petri net. The manufacturing application model drives the network platform that inversely provides this application model technology supports. The proposed multi-agent system is demonstrated through an example integration scenario involving production plan, resources management and execution subsystems. And the result suggests that analyzing and designing the system architecture of networked manufacturing should give due attention to the operation system as well as manufacturing applications.

  9. Architecture & Environment

    Science.gov (United States)

    Erickson, Mary; Delahunt, Michael

    2010-01-01

    Most art teachers would agree that architecture is an important form of visual art, but they do not always include it in their curriculums. In this article, the authors share core ideas from "Architecture and Environment," a teaching resource that they developed out of a long-term interest in teaching architecture and their fascination with the…

  10. The internationalization of Chinese industries : Overseas acquisition activity in Chinese mining and manufacturing industries

    NARCIS (Netherlands)

    Zhou, C.; van Witteloostuijn, A.; Zhang, J.

    2014-01-01

    This study examines how industrial characteristics at home affect Chinese overseas acquisition activities from an industry-level resource-based view. Analyzing data on 512 Chinese overseas acquisition deals across 36 industries in 60 countries over 2003–2008, we find that: (1) firms in industries wi

  11. Manufacture and Testing of an Activation Foil Package for Use in AFIDS

    Science.gov (United States)

    2005-03-01

    designed to capture fast and epithermal neutrons from any direction. Direction is not as important for thermal neutrons because thermal neutrons ... nuclear weapon neutron output, foil activation and the methodology used by ORNL to compare neutron spectra. Chapter III provides the foil package design ...SCALE simulations for N2O, air and liquid air. Liquid/Air Experiment Design An experiment using the beam port of the OSU research reactor was

  12. Low accessibility and chemical activity of PAHs restrict bioremediation and risk of exposure in a manufactured gas plant soil

    Energy Technology Data Exchange (ETDEWEB)

    Reichenberg, Fredrik; Karlson, Ulrich Gosewinkel [Department of Environmental Chemistry and Microbiology, National Environmental Research Institute, Aarhus University, P.O. Box 358, 4000 Roskilde (Denmark); Gustafsson, Orjan [Stockholm University, Department of Applied Environmental Science (ITM), 10691 Stockholm (Sweden); Long, Sara M. [Centre for Ecology and Hydrology, Monks Wood, Abbots Ripton, Huntingdon, Cambridgeshire PE28 2LS (United Kingdom); Pritchard, Parmely H. [Department of Environmental Chemistry and Microbiology, National Environmental Research Institute, Aarhus University, P.O. Box 358, 4000 Roskilde (Denmark); Department of Biology, Portland State University, PO Box 751, Portland, OR 97207 (United States); Mayer, Philipp, E-mail: phm@dmu.d [Department of Environmental Chemistry and Microbiology, National Environmental Research Institute, Aarhus University, P.O. Box 358, 4000 Roskilde (Denmark)

    2010-05-15

    Composting of manufactured gas plant soil by a commercial enterprise had removed most of its polycyclic aromatic hydrocarbons (PAHs), but concentrations remained above regulatory threshold levels. Several amendments and treatments were first tested to restart the PAH degradation, albeit with little success. The working hypothesis was then that PAHs were 'stuck' due to strong sorption to black carbon. Accessibility was measured with cyclodextrin extractions and on average only 4% of the PAHs were accessible. Chemical activity of the PAHs was measured by equilibrium sampling, which confirmed a low exposure level. These results are consistent with strong sorption to black carbon (BC), which constituted 59% of the total organic carbon. Composting failed to remove the PAHs, but it succeeded to minimize PAH accessibility and chemical activity. This adds to accumulating evidence that current regulatory thresholds based on bulk concentrations are questionable and alternative approaches probing actual risk should be considered. - Bioremediation of MGP soil failed to eliminate PAHs but it succeeded to limit their accessibility, chemical activity and the remaining risk of biological exposure.

  13. Effect of Copolymer Chain Architecture on Active Layer Morphology and Device Performance

    Science.gov (United States)

    Amonoo, Jojo; Li, Anton; Sykes, Matthew; Huang, Bingyuan; Palermo, Edmund; McNeil, Anne; Shtein, Max; Green, Peter

    2014-03-01

    The optimum morphological structure that determines the device performance of bulk heterojunction thin film polymer solar cells is greatly influenced by the extent of phase separation between the polymer and fullerene components, which ultimately defines the length scales and purity of the donor- and acceptor-rich phases. Block copolymer thin films have been widely studied for their ability to microphase separate into well-defined nanostructures. Nickel-catalyzed chain-growth copolymerizations of thiophene and selenophene derivatives afforded well-defined π-conjugated copolymers of poly(3-hexylthiophene) (P3HT) and poly(3-hexylselenophene) (P3HS) to achieve diblock, random and gradient copolymer chain architectures. This allowed us to study the effect of copolymer sequence and nanoscale morphology of P3HT-P3HS copolymer/[6,6]-phenyl-C61-butyric acid methyl ester (PC61BM) on device performance. With the use of energy-filtered transmission electron microscopy and conductive and photoconductive atomic force microscopy we found that copolymer sequence strongly influences the phase separation capabilities of the copolymer-fullerene blend in bulk heterojunction organic photovoltaic devices.

  14. Manufacturing technologies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    The Manufacturing Technologies Center is an integral part of Sandia National Laboratories, a multiprogram engineering and science laboratory, operated for the Department of Energy (DOE) with major facilities at Albuquerque, New Mexico, and Livermore, California. Our Center is at the core of Sandia`s Advanced Manufacturing effort which spans the entire product realization process.

  15. Manufacturing Interfaces

    NARCIS (Netherlands)

    Houten, van F.J.A.M.

    1992-01-01

    The paper identifies the changing needs and requirements with respect to the interfacing of manufacturing functions. It considers the manufacturing system, its components and their relationships from the technological and logistic point of view, against the background of concurrent engineering. Desi

  16. Manufacturing and testing a thin glass mirror shell with piezoelectric active control

    CERN Document Server

    Spiga, D; Collura, A; Basso, S; Candia, R; Civitani, M; Di Bella, M; Di Cicca, G; Cicero, U Lo; Lullo, G; Pelliciari, C; Riva, M; Salmaso, B; Sciortino, L; Varisco, S

    2016-01-01

    Optics for future X-ray telescopes will be characterized by very large aperture and focal length, and will be made of lightweight materials like glass or silicon in order to keep the total mass within acceptable limits. Optical modules based on thin slumped glass foils are being developed at various institutes, aiming at improving the angular resolution to a few arcsec HEW. Thin mirrors are prone to deform, so they require a careful integration to avoid deformations and even correct forming errors. On the other hand, this offers the opportunity to actively correct the residual deformation: a viable possibility to improve the mirror figure is the application of piezoelectric actuators onto the non-optical side of the mirrors, and several groups are already at work on this approach. The concept we are developing consists of actively integrating thin glass foils with piezoelectric patches, fed by voltages driven by the feedback provided by X-rays. The actuators are commercial components, while the tension signal...

  17. Formation mechanism, structural characterization, optical properties and photocatalytic activity of hierarchically arranged sisal-like ZnO architectures

    Science.gov (United States)

    Xu, Fen; Du, Gao-Hui; Halasa, Matej; Su, Bao-Lian

    2006-07-01

    A simple low-temperature solution-based self-construction approach has been demonstrated for fabricating the highly uniform assembly of ZnO nanocones with much higher aspect ratio, in which a highly non-equilibrium chemical environment favors for the large-scale generation of the complex architectures mimicking the sisal-like structures. The formation mechanism has been studied at molecular level. The optical and photocatalytic properties of the as-synthesized product have been correlated with their chemical composition, morphology and structural features. These sisal-like ZnO nanocone assemblies have shown a strong UV emission with a broad blue emission band and a high photocatalytic activity in decomposition of polyaromatics, suggesting their potentials in light and field emission and environmental applications.

  18. Active learning units interrelated using TIC’s tools in architectural construction

    Directory of Open Access Journals (Sweden)

    Núria Martí Audí

    2013-08-01

    Full Text Available 0 0 1 141 779 USAL 6 1 919 14.0 Normal 0 21 false false false ES JA X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0cm; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:Calibri; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-ansi-language:ES; mso-fareast-language:EN-US;} The presence of new technologies in the university world is a matter of fact. Nevertheless, it has not always blended correctly as in many cases TIC incorporation has not taken alumni opinion understood as final users. A correct implementation might evaluate some variables as satisfaction, need, interest and finally that versatility to adapt it to proficient professional training on a regular basis. This paper analyses a new approach to learning in the field of Architectural Construction based on a series of strategically designed and interactive units. The centre of these is the collaborative project; this is based on complex problem-solving situations akin to the professional world; where theory and practice are combined in a discovery-learning process. The tools of Information and Communication Technology are applied, simultaneously facilitating the student’s autonomy in acquiring skills and knowledge.

  19. Controlling the molecular architecture of lactase immobilized in Langmuir-Blodgett films of phospholipids to modulate the enzyme activity.

    Science.gov (United States)

    Ayoub, Fábio de Paula; Caseli, Luciano

    2017-02-01

    In this present work, the adsorption of the enzyme lactase onto Langmuir monolayers of the phospholipid dimyristoylphosphatidic acid (DMPA) was investigated and characterized with surface pressure-area isotherms, surface potential-area isotherms and polarization-modulated infrared reflection-absorption spectroscopy (PM-IRRAS). The adsorption of the enzyme at the air-water interface expanded the lipid monolayer and increased the film compressibility at high surface pressures. Amide bands in the PM-IRRAS spectra were identified, with the CN and CO dipole moments lying parallel to the monolayer plane, revealing that the structuring of the enzyme into β-sheets was kept in the mixed monolayer. The enzyme-lipid films were transferred from the floating monolayer to solid supports as Langmuir-Blodgett (LB) films and characterized with fluorescence spectroscopy and atomic force microscopy. The catalytic activity of the films was measured and compared to the homogenous medium. The enzyme accommodated in the LB films preserved more than 80% of the enzyme activity after 20days, in contrast for the homogeneous medium, which preserved less than 60% of the enzyme activity. The method presented in this present work not only allows for an enhanced catalytic activity toward lactose, but also can help explain why certain film architectures exhibit better performance.

  20. Alkali treatment of microrough titanium surfaces affects macrophage/monocyte adhesion, platelet activation and architecture of blood clot formation

    Directory of Open Access Journals (Sweden)

    V Milleret

    2011-05-01

    Full Text Available Titanium implants are most commonly used for bone augmentation and replacement due to their favorable osseointegration properties. Here, hyperhydrophilic sand-blasted and acid-etched (SBA titanium surfaces were produced by alkali treatment and their responses to partially heparinized whole human blood were analyzed. Blood clot formation, platelet activation and activation of the complement system was analyzed revealing that exposure time between blood and the material surface is crucial as increasing exposure time results in higher amount of activated platelets, more blood clots formed and stronger complement activation. In contrast, the number of macrophages/monocytes found on alkali-treated surfaces was significantly reduced as compared to untreated SBA Ti surfaces. Interestingly, when comparing untreated to modified SBA Ti surfaces very different blood clots formed on their surfaces. On untreated Ti surfaces blood clots remain thin (below 15 mm, patchy and non-structured lacking large fibrin fiber networks whereas blood clots on differentiated surfaces assemble in an organized and layered architecture of more than 30 mm thickness. Close to the material surface most nucleated cells adhere, above large amounts of non-nucleated platelets remain entrapped within a dense fibrin fiber network providing a continuous cover of the entire surface. These findings might indicate that, combined with findings of previous in vivo studies demonstrating that alkali-treated SBA Ti surfaces perform better in terms of osseointegration, a continuous and structured layer of blood components on the blood-facing surface supports later tissue integration of an endosseous implant.

  1. Manufacturing of Porous Al-Cr Preforms for Composite Reinforcing Using Microwave Activated Combustion Synthesis

    Directory of Open Access Journals (Sweden)

    Naplocha K.

    2014-10-01

    Full Text Available The combustion synthesis of porous skeletons (preforms of intermetallic Al–Cr compounds intended for metal matrix composite MMC reinforcing was developed. Mixture of Al and Cr powders with granularity of −10, −44, −74mm were cold isostatic pressed and next ignited and synthetized in a microwave reactor under argon atmosphere (microwave-activated combustion synthesis MACS. In order to ignite the synthesis, microwave energy was focused by a tuner on the specimen. The analysis of reaction temperature diagrams revealed that the synthesis proceeded through the following peritectic transformations: L(liquidus+Al7Cr→L+Al11Cr2→L+Al4Cr. Moreover, EDS and XRD examinations showed that the reaction proceeded between a solid Cr and a liquid Al to create a distinct envelope of Al9Cr4 on Cr particle which next extended and spreaded over the entire structure. The produced preforms with uniform structure and interconnected porosity were infiltrated with liquid Cu and Al alloy. The obtained composite materials exhibited high hardness, wear and distinct temperature oxidation resistance.

  2. Architectural freedom and industrialised architecture

    DEFF Research Database (Denmark)

    Vestergaard, Inge

    2012-01-01

    compares "best practice" in Denmark and "best practice" in Austria. The modern architects accepted the fact that industrialized architecture told the storey of repetition and monotonous as basic condition. This article aims to explain that architecture can be thought as a complex and diverse design through......Architectural freedom and industrialized architecture. Inge Vestergaard, Associate Professor, Cand. Arch. Aarhus School of Architecture, Denmark Noerreport 20, 8000 Aarhus C Telephone +45 89 36 0000 E-mai l inge.vestergaard@aarch.dk Based on the repetitive architecture from the "building boom" 1960...... to 1973 it is discussed how architects can handle these Danish element and montage buildings through the transformation to upgraded aesthetical, functional and energy efficient architecture. The method used is analysis of cases, parallels to literature studies and producer interviews. This analysis...

  3. Detail in architecture: Between arts & crafts

    Science.gov (United States)

    Dulencin, Juraj

    2016-06-01

    Architectural detail represents an important part of architecture. Not only can it be used as an identifier of a specific building but at the same time enhances the experience of the realized project. Within it lie the signs of a great architect and clues to understanding his or her way of thinking. It is therefore the central topic of a seminar offered to architecture students at the Brno University of Technology. During the course of the semester-long class the students acquaint themselves with atypical architectural details of domestic and international architects by learning to read them, understand them and subsequently draw them by creating architectural blueprints. In other words, by general analysis of a detail the students learn theoretical thinking of its architect who, depending on the nature of the design, had to incorporate a variety of techniques and crafts. Students apply this analytical part to their own architectural detail design. The methodology of the seminar consists of experiential learning by project management and is complemented by a series of lectures discussing a diversity of details as well as materials and technologies required to implement it. The architectural detail design is also part of students' bachelors thesis, therefore, the realistic nature of their blueprints can be verified in the production process of its physical counterpart. Based on their own documentation the students choose the most suitable manufacturing process whether it is supplied by a specific technology or a craftsman. Students actively participate in the production and correct their design proposals in real scale with the actual material. A student, as a future architect, stands somewhere between a client and an artisan, materializes his or her idea and adjusts the manufacturing process so that the final detail fulfills aesthetic consistency and is in harmony with its initial concept. One of the very important aspects of the design is its economic cost, an

  4. Service Manufacturings Strategy of Value Creation Analysis of R & D Activity in Chinas Manufacturing Enterprises%服务型制造战略下中国制造企业研发活动价值创造分析

    Institute of Scientific and Technical Information of China (English)

    吴安波; 孙林岩; 杨才君; 张颖

    2012-01-01

    here are many new issues in R&D research area, such as R&D conception lag behind, lack of efficient organization structure, inefficient process, weak R&D independent capacity, and loose connection with market, while Chinese manufacturing enterprises are restructuring and shifting their innovation system and service system. This paper constructs a value creation system of R&D activity for Chinese manufacturing enterprises in the period of transition; summarizes current R&D problems of manufacturing enterprises in China, and analyzes the characteristics of value creation for R&D activity based on Service Manufacturing strategy. Then it is proposed to carry out collaborative R&D and R&D outsourcing strategy based on Service Manufacturing network; implement open R&D strategy oriented by customer demand; develop customer engagement, suppliers involvement in R&D activities; and let valid R&D cost management, project management and performance management support strategy implementation.%我国制造企业的服务转型及创新体系转型引发了传统制造企业研发观念落后、组织架构不合理、流程效率低、自主研发能力弱、与市场联系不紧密等研发问题.针对这些问题,构建了转型期中国制造企业的价值创造活动体系,并以研发活动为例,分析了我国制造企业的研发现状,研究了服务型制造下研发活动价值创造的特征,在此基础上提出:①开展基于服务型制造网络的合作研发与研发外包;②以客户需求为研发导向,实施开放式研发战略;③发展客户和供应商参与研发;④依靠有效的研发成本管理、研发项目管理和研发绩效管理提供辅助支持的合作创新模式.

  5. Early activation of quorum sensing in Pseudomonas aeruginosa reveals the architecture of a complex regulon

    Directory of Open Access Journals (Sweden)

    Schuster Martin

    2007-08-01

    , or that expression is controlled posttranscriptionally. This architecture permits the integration of multiple signaling pathways resulting in quorum responses that require a "quorum" but are otherwise highly adaptable and receptive to environmental conditions.

  6. Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function

    Science.gov (United States)

    Muhammad, Karzan; Reddy-Alla, Suneel; Driller, Jan H; Schreiner, Dietmar; Rey, Ulises; Böhme, Mathias A.; Hollmann, Christina; Ramesh, Niraja; Depner, Harald; Lützkendorf, Janine; Matkovic, Tanja; Götz, Torsten; Bergeron, Dominique D.; Schmoranzer, Jan; Goettfert, Fabian; Holt, Mathew; Wahl, Markus C.; Hell, Stefan W.; Scheiffele, Peter; Walter, Alexander M.; Loll, Bernhard; Sigrist, Stephan J.

    2015-01-01

    Assembly and maturation of synapses at the Drosophila neuromuscular junction (NMJ) depend on trans-synaptic neurexin/neuroligin signalling, which is promoted by the scaffolding protein Syd-1 binding to neurexin. Here we report that the scaffold protein spinophilin binds to the C-terminal portion of neurexin and is needed to limit neurexin/neuroligin signalling by acting antagonistic to Syd-1. Loss of presynaptic spinophilin results in the formation of excess, but atypically small active zones. Neuroligin-1/neurexin-1/Syd-1 levels are increased at spinophilin mutant NMJs, and removal of single copies of the neurexin-1, Syd-1 or neuroligin-1 genes suppresses the spinophilin-active zone phenotype. Evoked transmission is strongly reduced at spinophilin terminals, owing to a severely reduced release probability at individual active zones. We conclude that presynaptic spinophilin fine-tunes neurexin/neuroligin signalling to control active zone number and functionality, thereby optimizing them for action potential-induced exocytosis. PMID:26471740

  7. Research of Manufacture Time Management System Based on PLM

    Science.gov (United States)

    Jing, Ni; Juan, Zhu; Liangwei, Zhong

    This system is targeted by enterprises manufacturing machine shop, analyzes their business needs and builds the plant management information system of Manufacture time and Manufacture time information management. for manufacturing process Combined with WEB technology, based on EXCEL VBA development of methods, constructs a hybrid model based on PLM workshop Manufacture time management information system framework, discusses the functionality of the system architecture, database structure.

  8. Software architecture

    CERN Document Server

    Vogel, Oliver; Chughtai, Arif

    2011-01-01

    As a software architect you work in a wide-ranging and dynamic environment. You have to understand the needs of your customer, design architectures that satisfy both functional and non-functional requirements, and lead development teams in implementing the architecture. And it is an environment that is constantly changing: trends such as cloud computing, service orientation, and model-driven procedures open up new architectural possibilities. This book will help you to develop a holistic architectural awareness and knowledge base that extends beyond concrete methods, techniques, and technologi

  9. Green Architecture

    Science.gov (United States)

    Lee, Seung-Ho

    Today, the environment has become a main subject in lots of science disciplines and the industrial development due to the global warming. This paper presents the analysis of the tendency of Green Architecture in France on the threes axes: Regulations and Approach for the Sustainable Architecture (Certificate and Standard), Renewable Materials (Green Materials) and Strategies (Equipments) of Sustainable Technology. The definition of 'Green Architecture' will be cited in the introduction and the question of the interdisciplinary for the technological development in 'Green Architecture' will be raised up in the conclusion.

  10. Micro Manufacturing

    DEFF Research Database (Denmark)

    Hansen, Hans Nørgaard

    2003-01-01

    Manufacturing deals with systems that include products, processes, materials and production systems. These systems have functional requirements, constraints, design parameters and process variables. They must be decomposed in a systematic manner to achieve the best possible system performance....... If a micro manufacturing system isn’t designed rationally and correctly, it will be high-cost, unreliable, and not robust. For micro products and systems it is a continuously increasing challenge to create the operational basis for an industrial production. As the products through product development...... processes are made applicable to a large number of customers, the pressure in regard to developing production technologies that make it possible to produce the products at a reasonable price and in large numbers is growing. The micro/nano manufacturing programme at the Department of Manufacturing...

  11. Smart Manufacturing.

    Science.gov (United States)

    Davis, Jim; Edgar, Thomas; Graybill, Robert; Korambath, Prakashan; Schott, Brian; Swink, Denise; Wang, Jianwu; Wetzel, Jim

    2015-01-01

    Historic manufacturing enterprises based on vertically optimized companies, practices, market share, and competitiveness are giving way to enterprises that are responsive across an entire value chain to demand dynamic markets and customized product value adds; increased expectations for environmental sustainability, reduced energy usage, and zero incidents; and faster technology and product adoption. Agile innovation and manufacturing combined with radically increased productivity become engines for competitiveness and reinvestment, not simply for decreased cost. A focus on agility, productivity, energy, and environmental sustainability produces opportunities that are far beyond reducing market volatility. Agility directly impacts innovation, time-to-market, and faster, broader exploration of the trade space. These changes, the forces driving them, and new network-based information technologies offering unprecedented insights and analysis are motivating the advent of smart manufacturing and new information technology infrastructure for manufacturing.

  12. Composite Event Specification and Detection for Supporting Active Capability in an OODBMS: Semantics Architecture and Implementation.

    Science.gov (United States)

    1995-03-01

    For all outgoing edges i from ’n’ propagate parameters in node ’n’ to the nodei connected by edge i activate-operator-node( nodej ); Delete propagated...El E2 Figure 6: Detection of X in recent mode PROCEDURE activate-operator-node( nodej ) /* Recent Context */ CASE nodei is of type a primitive or...composite event has been signalled to nodej */ AND(E1, E2): if left event el is signalled if E2’s list is not empty Pass <e2, el> to the parent Replace el in

  13. Inhibitory activity of Lactobacillus plantarum TF711 against Clostridium sporogenes when used as adjunct culture in cheese manufacture.

    Science.gov (United States)

    González, Lorena; Zárate, Victoria

    2015-05-01

    Bacteriocins produced by lactic acid bacteria are of great interest to the food-processing industry as natural preservatives. This work aimed to investigate the efficacy of bacteriocin-producing Lactobacillus plantarum TF711, isolated from artisanal Tenerife cheese, in controlling Clostridium sporogenes during cheese ripening. Cheeses were made from pasteurised milk artificially contaminated with 10(4) spores m/l C. sporogenes. Experimental cheeses were manufactured with Lb. plantarum TF711 added at 1% as adjunct to commercial starter culture. Cheeses made under the same conditions but without Lb. plantarum TF711 served as controls. Evolution of microbiological parameters, pH and NaCl content, as well as bacteriocin production was studied throughout 45 d of ripening. Addition of Lb. plantarum TF711 did not bring about any significant change in starter culture counts, NaCl content and pH, compared with control cheese. In contrast, clostridial spore count in experimental cheeses were significantly lower than in control cheeses from 7 d onwards, reaching a maximum reduction of 2·2 log units on day 21. Inhibition of clostridia found in experimental cheeses was mainly attributed to plantaricin activity, which in fact was recovered from these cheeses.

  14. Inter-rater reliability of cyclic and non-cyclic task assessment using the hand activity level in appliance manufacturing.

    Science.gov (United States)

    Paulsen, Robert; Schwatka, Natalie; Gober, Jennifer; Gilkey, David; Anton, Dan; Gerr, Fred; Rosecrance, John

    2014-01-01

    This study evaluated the inter-rater reliability of the American Conference of Governmental Industrial Hygienists (ACGIH(®)) hand activity level (HAL), an observational ergonomic assessment method used to estimate physical exposure to repetitive exertions during task performance. Video recordings of 858 cyclic and non-cyclic appliance manufacturing tasks were assessed by sixteen pairs of raters using the HAL visual-analog scale. A weighted Pearson Product Moment-Correlation Coefficient was used to evaluate the agreement between the HAL scores recorded by each rater pair, and the mean weighted correlation coefficients for cyclic and non-cyclic tasks were calculated. Results indicated that the HAL is a reliable exposure assessment method for cyclic (r̄-bar w = 0.69) and non-cyclic work tasks (r̄-bar w = 0.68). When the two reliability scores were compared using a two-sample Student's t-test, no significant difference in reliability (p = 0.63) between these work task categories was found. This study demonstrated that the HAL may be a useful measure of exposure to repetitive exertions during cyclic and non-cyclic tasks.

  15. Processes for an Architecture of Volume

    DEFF Research Database (Denmark)

    Mcgee, Wes; Feringa, Jelle; Søndergaard, Asbjørn

    2013-01-01

    This paper addresses both the architectural, conceptual motivations and the tools and techniques necessary for the digital production of an architecture of volume. The robotic manufacturing techniques of shaping volumetric materials by hot wire and abrasive wire cutting are discussed through...

  16. ACTIVITY OF AUTHORITIES ON DEVELOPMENT OF MANUFACTURE OF COMBINE HARVESTERS IN ROSTOV AREA IN 1966‒1975

    Directory of Open Access Journals (Sweden)

    O. I. ALEKSEENKO

    2016-01-01

    Full Text Available In article on basis of published and archival documents, research literature activity of party-state bodies on development of agricultural mechanical engineering in Rostov area within 8-th and 9-th five-year periods is considered. In article decisions March and September 1965 of Plenums of Central Committee of CPSU, instruction and decision of XXIII congress of CPSU, Ministerial council of USSR, developed bases of an agrarian policy of party and state during investigated period, put before the enterprises of agricultural and tractor mechanical engineering specific targets are studied. Author in detail shines actions, spent under direction of state authorities, Rostov regional committee of CPSU and local party organizations, on leading enterprises of branch – Rostov factory of agricultural mechanical engineering (Rostselmash and Taganrog factory of combines: development and release of new models of combine harvesters, their subsequent updating, modernization of manufacture and management, distribution of advanced methods of organization of work. Author has shown wide attraction to decision of complex industrial problems of technical and economic advice (TEA, Taganrog State special design office (TSSDO, public organizations (scientific and technical society (STS to machine engineering industry, trade unions, Komsomol, public design offices, inventors and rationalizers, technical officers (TO, scientists, innovators of manufacture. In article high competitiveness of combines SK-4, ”Field”, “Ear”, “Don”, issued by these factories in 1960-1980, in the world market is noted. Author does conclusion about necessity of use of experience, saved up in Soviet period, during restoration of agricultural mechanical engineering, and also support from bodies of government and management of modern Russia.

  17. Evaluation of Agile Manufacturing Enterprises%Evaluation of Agile Manufacturing Enterprises

    Institute of Scientific and Technical Information of China (English)

    黄新刚; 王先逵; 刘成颖

    2001-01-01

    Agile manufacturing is an important manufacturing philosophy todevelop advanced manufacturing enterprises to improve competivity. The evaluation of Agile Manufacturing Enterprises (AME) is one of the key activities in implementing agile manufacturing. This paper proposes a method for evaluating AME, establishes a basic feature model of AME based on the feature tree and discusses the hierarchical decomposition algorithm based on the model with an example.

  18. The architecture of the active surface control system of the Large Millimeter Telescope

    Science.gov (United States)

    Souccar, Kamal; Wallace, Gary; Grosslein, Ron; Schloerb, F. Peter

    2014-07-01

    One of the fundamental design principles of the LMT is that its segmented primary surface must be active: the position and orientation of each of the segments must be moved in order to maintain the precise parabolic surface that is required by the specifications. Consequently, a system of actuators, one at the corner of each segment, is used to move the segments to counteract surface deformations attributed to gravity or thermal effects. A new control system was designed and built within the project to implement an active surface at the LMT. The technical concept for the active surface control system is to provide a set of bus boxes with built-in control and I/O capabilities to run four actuators each. Bus boxes read the LVDT sensor position and limit switch status for each actuator and use this information to drive the actuator's DC motor, closing the position loop. Each bus box contains a DC power supply for the electronics, a second DC power supply for the motors, an embedded controller with I/O to close the position loop, and a custom printed circuit board to condition the LVDT signals and drive the motors. An interface printed circuit board resides in each actuator providing a single connector access to the LVDT, the motor, and the limit switches. During the fall of 2013, 84 bus boxes were commissioned to control the 336 actuators of the inner three rings of the telescope. The surface correction model was determined using holography measurements and the active surface system has been in regular use during the scientific observation at the LMT.

  19. Enzyme Architecture: The Activating Oxydianion Binding Domain for Orotidine 5′-Monophophate Decarboxylase

    Science.gov (United States)

    Spong, Krisztina; Amyes, Tina L.; Richard, John P.

    2014-01-01

    Orotidine 5′-monophosphate decarboxylase catalyzes the decarboxylation of truncated substrate (1-β-D-erythrofuranosyl)orotic acid (EO) to form (1-β-D-erythrofuranosyl)uracil (EU). This enzymecatalyzed reaction is activated by tetrahedral oxydianions, which bind weakly to unliganded OMPDC and tightly to the enzyme-transition state complex, with the following intrinsic oxydianion binding energies (kcal/mole): SO32−, −8.3; HPO32−, −7.7; S2O32−, −4.6; SO42−, −4.5; HOPO32−, −3.0; HOAsO32−, no activation detected. We propose that oxydianion and orotate binding domains perform complementary functions in catalysis of decarboxylation reactions. (1) The orotate binding domain carries out decarboxylation of the orotate ring. (2) The activating oxydianion binding domain has the cryptic function of utilizing binding interactions with tetrahedral inorganic oxydianions to drive an enzyme conformational change that results in the stabilization of transition states at the distant orotate domain. PMID:24274746

  20. Enzyme architecture: the activating oxydianion binding domain for orotidine 5'-monophophate decarboxylase.

    Science.gov (United States)

    Spong, Krisztina; Amyes, Tina L; Richard, John P

    2013-12-11

    Orotidine 5'-monophosphate decarboxylase catalyzes the decarboxylation of truncated substrate (1-β-D-erythrofuranosyl)orotic acid to form (1-β-D-erythrofuranosyl)uracil. This enzyme-catalyzed reaction is activated by tetrahedral oxydianions, which bind weakly to unliganded OMPDC and tightly to the enzyme-transition state complex, with the following intrinsic oxydianion binding energies (kcal/mol): SO3(2-), -8.3; HPO3(2-), -7.7; S2O3(2-), -4.6; SO4(2-), -4.5; HOPO3(2-), -3.0; HOAsO3(2-), no activation detected. We propose that the oxydianion and orotate binding domains of OMPDC perform complementary functions in catalysis of decarboxylation reactions: (1) The orotate binding domain carries out decarboxylation of the orotate ring. (2) The activating oxydianion binding domain has the cryptic function of utilizing binding interactions with tetrahedral inorganic oxydianions to drive an enzyme conformational change that results in the stabilization of transition states at the distant orotate domain.

  1. The functional architecture of the human body: assessing body representation by sorting body parts and activities.

    Science.gov (United States)

    Bläsing, Bettina; Schack, Thomas; Brugger, Peter

    2010-05-01

    We investigated mental representations of body parts and body-related activities in two subjects with congenitally absent limbs (one with, the other without phantom sensations), a wheelchair sports group of paraplegic participants, and two groups of participants with intact limbs. To analyse mental representation structures, we applied Structure Dimensional Analysis. Verbal labels indicating body parts and related activities were presented in randomized lists that had to be sorted according to a hierarchical splitting paradigm. Participants were required to group the items according to whether or not they were considered related, based on their own body perception. Results of the groups of physically intact and paraplegic participants revealed separate clusters for the lower body, upper body, fingers and head. The participant with congenital phantom limbs also showed a clear separation between upper and lower body (but not between fingers and hands). In the participant without phantom sensations of the absent arms, no such modularity emerged, but the specific practice of his right foot in communication and daily routines was reflected. Sorting verbal labels of body parts and activities appears a useful method to assess body representation in individuals with special body anatomy or function and leads to conclusions largely compatible with other assessment procedures.

  2. Nuclear envelope lamin-A couples actin dynamics with immunological synapse architecture and T cell activation.

    Science.gov (United States)

    González-Granado, José M; Silvestre-Roig, Carlos; Rocha-Perugini, Vera; Trigueros-Motos, Laia; Cibrián, Danay; Morlino, Giulia; Blanco-Berrocal, Marta; Osorio, Fernando G; Freije, José M P; López-Otín, Carlos; Sánchez-Madrid, Francisco; Andrés, Vicente

    2014-04-22

    In many cell types, nuclear A-type lamins regulate multiple cellular functions, including higher-order genome organization, DNA replication and repair, gene transcription, and signal transduction; however, their role in specialized immune cells remains largely unexplored. We showed that the abundance of A-type lamins was almost negligible in resting naïve T lymphocytes, but was increased upon activation of the T cell receptor (TCR). The increase in lamin-A was an early event that accelerated formation of the immunological synapse between T cells and antigen-presenting cells. Polymerization of F-actin in T cells is a critical step for immunological synapse formation, and lamin-A interacted with the linker of nucleoskeleton and cytoskeleton (LINC) complex to promote F-actin polymerization. We also showed that lamin-A expression accelerated TCR clustering and led to enhanced downstream signaling, including extracellular signal-regulated kinase 1/2 (ERK1/2) signaling, as well as increased target gene expression. Pharmacological inhibition of the ERK pathway reduced lamin-A-dependent T cell activation. Moreover, mice lacking lamin-A in immune cells exhibited impaired T cell responses in vivo. These findings underscore the importance of A-type lamins for TCR activation and identify lamin-A as a previously unappreciated regulator of the immune response.

  3. Matrix stiffness modulates formation and activity of neuronal networks of controlled architectures.

    Science.gov (United States)

    Lantoine, Joséphine; Grevesse, Thomas; Villers, Agnès; Delhaye, Geoffrey; Mestdagh, Camille; Versaevel, Marie; Mohammed, Danahe; Bruyère, Céline; Alaimo, Laura; Lacour, Stéphanie P; Ris, Laurence; Gabriele, Sylvain

    2016-05-01

    The ability to construct easily in vitro networks of primary neurons organized with imposed topologies is required for neural tissue engineering as well as for the development of neuronal interfaces with desirable characteristics. However, accumulating evidence suggests that the mechanical properties of the culture matrix can modulate important neuronal functions such as growth, extension, branching and activity. Here we designed robust and reproducible laminin-polylysine grid micropatterns on cell culture substrates that have similar biochemical properties but a 100-fold difference in Young's modulus to investigate the role of the matrix rigidity on the formation and activity of cortical neuronal networks. We found that cell bodies of primary cortical neurons gradually accumulate in circular islands, whereas axonal extensions spread on linear tracks to connect circular islands. Our findings indicate that migration of cortical neurons is enhanced on soft substrates, leading to a faster formation of neuronal networks. Furthermore, the pre-synaptic density was two times higher on stiff substrates and consistently the number of action potentials and miniature synaptic currents was enhanced on stiff substrates. Taken together, our results provide compelling evidence to indicate that matrix stiffness is a key parameter to modulate the growth dynamics, synaptic density and electrophysiological activity of cortical neuronal networks, thus providing useful information on scaffold design for neural tissue engineering.

  4. Local architecture

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Local architecture refers to structures built in the countryside,such as temples,memorial halls,residences, stores,pavilions, bridges,decorated archways, and wells. Because these structures were all built by focal craftsmen and villagers in the traditional local style, they are generally called local architecture.

  5. Architecture Sustainability

    NARCIS (Netherlands)

    Avgeriou, Paris; Stal, Michael; Hilliard, Rich

    2013-01-01

    Software architecture is the foundation of software system development, encompassing a system's architects' and stakeholders' strategic decisions. A special issue of IEEE Software is intended to raise awareness of architecture sustainability issues and increase interest and work in the area. The fir

  6. Architectural Contestation

    NARCIS (Netherlands)

    Merle, J.

    2012-01-01

    This dissertation addresses the reductive reading of Georges Bataille's work done within the field of architectural criticism and theory which tends to set aside the fundamental ‘broken’ totality of Bataille's oeuvre and also to narrowly interpret it as a mere critique of architectural form, consequ

  7. Architectural geometry

    NARCIS (Netherlands)

    Pottmann, Helmut; Eigensatz, Michael; Vaxman, A.; Wallner, Johannes

    2015-01-01

    Around 2005 it became apparent in the geometry processing community that freeform architecture contains many problems of a geometric nature to be solved, and many opportunities for optimization which however require geometric understanding. This area of research, which has been called architectural

  8. Architectural Narratives

    DEFF Research Database (Denmark)

    Kiib, Hans

    2010-01-01

    and architectural heritage; another group tries to embed new performative technologies in expressive architectural representation. Finally, this essay provides a theoretical framework for the analysis of the political rationales of these projects and for the architectural representation bridges the gap between......In this essay, I focus on the combination of programs and the architecture of cultural projects that have emerged within the last few years. These projects are characterized as “hybrid cultural projects,” because they intend to combine experience with entertainment, play, and learning. This essay...... identifies new rationales related to this development, and it argues that “cultural planning” has increasingly shifted its focus from a cultural institutional approach to a more market-oriented strategy that integrates art and business. The role of architecture has changed, too. It not only provides...

  9. Architectural Theatricality

    DEFF Research Database (Denmark)

    Tvedebrink, Tenna Doktor Olsen

    This PhD thesis is motived by a personal interest in the theoretical, practical and creative qualities of architecture. But also a wonder and curiosity about the cultural and social relations architecture represents through its occupation with both the sciences and the arts. Inspired by present...... initiatives in Aalborg Hospital to overcome patient undernutrition by refurbishing eating environments, this thesis engages in an investigation of the interior architectural qualities of patient eating environments. The relevance for this holistic perspective, synthesizing health, food and architecture...... environments and a knowledge gap therefore exists in present hospital designs. Consequently, the purpose of this thesis has been to investigate if any research-based knowledge exist supporting the hypothesis that the interior architectural qualities of eating environments influence patient food intake, health...

  10. Architectural Theatricality

    DEFF Research Database (Denmark)

    Tvedebrink, Tenna Doktor Olsen

    and well-being, as well as outline a set of basic design principles ‘predicting’ the future interior architectural qualities of patient eating environments. Methodologically the thesis is based on an explorative study employing an abductive approach and hermeneutic-interpretative strategy utilizing tactics......This PhD thesis is motived by a personal interest in the theoretical, practical and creative qualities of architecture. But also a wonder and curiosity about the cultural and social relations architecture represents through its occupation with both the sciences and the arts. Inspired by present...... initiatives in Aalborg Hospital to overcome patient undernutrition by refurbishing eating environments, this thesis engages in an investigation of the interior architectural qualities of patient eating environments. The relevance for this holistic perspective, synthesizing health, food and architecture...

  11. Summary Report for the Technical Interchange Meeting on Development of Baseline Material Properties and Design Guidelines for In-Space Manufacturing Activities

    Science.gov (United States)

    Prater, T. J.; Bean, Q. A.; Werkheiser, N. J.; Johnston, M. M.; Ordonez, E. A.; Ledbetter, F. E.; Risdon, D. L.; Stockman, T. J.; Sandridge, S. K. R.; Nelson, G. M.

    2016-01-01

    NASA Marshall Space Flight Center (MSFC) and the Agency as a whole are currently engaged in a number of in-space manufacturing (ISM) activities that have the potential to reduce launch costs, enhance crew safety, and provide the capabilities needed to undertake long-duration spaceflight. The recent 3D Printing in Zero-G experiment conducted on board the International Space Station (ISS) demonstrated that parts of acrylonitrile butadiene styrene (ABS) plastic can be manufactured in microgravity using fused deposition modeling (FDM). This project represents the beginning of the development of a capability that is critical to future NASA missions. Current and future ISM activities will require the development of baseline material properties to facilitate design, analysis, and certification of materials manufactured using in-space techniques. The purpose of this technical interchange meeting (TIM) was to bring together MSFC practitioners and experts in materials characterization and development of baseline material properties for emerging technologies to advise the ISM team as we progress toward the development of material design values, standards, and acceptance criteria for materials manufactured in space. The overall objective of the TIM was to leverage MSFC's shared experiences and collective knowledge in advanced manufacturing and materials development to construct a path forward for the establishment of baseline material properties, standards development, and certification activities related to ISM. Participants were asked to help identify research and development activities that will (1) accelerate acceptance and adoption of ISM techniques among the aerospace design community; (2) benefit future NASA programs, commercial technology developments, and national needs; and (3) provide opportunities and avenues for further collaboration.

  12. The Activity-Based Computing Project - A Software Architecture for Pervasive Computing Final Report

    DEFF Research Database (Denmark)

    Bardram, Jakob Eyvind

    done. Moreover, partly based on the research done in the ABC project, the company Cetrea A/S has been founded, which incorporate ABC concepts and technologies in its products. The concepts of activity-based computing have also been researched in cooperation with IBM Research, and the ABC project has...... to delays in recruitment. This delay has not had any impact on the results obtain; on the contrary. From a research management point-of-view, the project has learned us several lessons, which are being incorporated into the management of current research project at ITU. The research on the ABC concepts...

  13. High Integrated Microwave Architecture Using LTCC-SIP Technology in Active Phased Array Antenna Applications

    Science.gov (United States)

    Zhou, Jun; Shi, Wei; Dou, Wen-Bin; Shen, Ya

    2012-06-01

    A kind of three dimensional Low Temperature Co-fired Ceramic (LTCC)-System in Package (SIP) transition was proposed in this paper. The basic design of SIP with LTCC technology was done by vertical transitions which transmit the microwave signal from the bottom to the surface of the substrate. The measured insertion loss did not exceed 1.5 dB, which contains the insertion loss of the test board about 0.6 dB at 18 GHz and the return loss was better than-15 dB up to 18 GHz. Then this technology was applied to a kind of phase shifting and amplifier module with two output ports. Basing on this module, a miniature Ku-band active phase array antenna was realized. The design results in a small size(84.8 mm×84.8 mm×55 mm). The measured performance of systems radiation pattern was also given.

  14. Effect of adenosine on the supramolecular architecture and activity of 5-fluorouracil

    Science.gov (United States)

    Singh, Udai P.; Kashyap, Sujata; Singh, Hari Ji; Mishra, Bhupesh Kumar; Roy, Partha; Chakraborty, Ajanta

    2012-04-01

    The reactions of adenosine (Ad) with 5-halouracils (5XU where X = F for 1, Cl for 2, Br for 3 and I for 4) resulted in the formation of co-crystals 1-4 in monoclinic with P21 space group. Despite of great variation in the halo substituent at the 5th position of the uracil, each structure contains the same number and same type of non-covalent interactions i.e., primary N-H⋯N, N-H⋯O, O-H⋯N, O-H⋯O hydrogen bonds and secondary C-H⋯O and X⋯O interactions within these motifs as well as with neighboring molecules. As compared to Ad the size of cavity increases in co-crystal 1 to accommodate the 5FU as a guest. With the variation of halogen from fluoro to iodo on the uracil, the orientation of the molecules remains the same with a slight difference in the dihedral angle in all the co-crystals 1-4. This study demonstrates that hydrogen-bonded interactions between adenosine and halouracils provide a supramolecular assembly to these co-crystals. Computational studies illustrate that the size of the halo substituents on uracil has no effect on the hydrogen bond interaction energy. It further reveals that the orientation of molecules remain same in both solid phase as well as in the gaseous phase. The antitumor and DNA cleavage activity studies show that the antitumor activity of 5-fluorouracil against MCF-7 breast cancer decreases in the presence of adenosine.

  15. ATPase site architecture is required for self-assembly and remodeling activity of a hexameric AAA+ transcriptional activator.

    Science.gov (United States)

    Joly, Nicolas; Zhang, Nan; Buck, Martin

    2012-08-10

    AAA+ proteins (ATPases associated with various cellular activities) are oligomeric ATPases that use ATP hydrolysis to remodel their substrates. By similarity with GTPases, a dynamic organization of the nucleotide-binding pockets between ATPase protomers is proposed to regulate functionality. Using the transcription activator PspF as an AAA+ model, we investigated contributions of conserved residues for roles in ATP hydrolysis and intersubunit communication. We determined the R-finger residue and revealed that it resides in a conserved "R-hand" motif (R(x)D(xxx)R) needed for its "trans-acting" activity. Further, a divergent Walker A glutamic acid residue acts synergistically with a tyrosine residue to function in ADP-dependent subunit-subunit coordination, forming the "ADP-switch" motif. Another glutamic acid controls hexamer formation in the presence of nucleotides. Together, these results lead to a "residue-nucleotide" interaction map upon which to base AAA+ core regulation.

  16. Design of a specific activator for skeletal muscle sodium channels uncovers channel architecture.

    Science.gov (United States)

    Cohen, Lior; Ilan, Nitza; Gur, Maya; Stühmer, Walter; Gordon, Dalia; Gurevitz, Michael

    2007-10-05

    Gating modifiers of voltage-gated sodium channels (Na(v)s) are important tools in neuroscience research and may have therapeutic potential in medicinal disorders. Analysis of the bioactive surface of the scorpion beta-toxin Css4 (from Centruroides suffusus suffusus) toward rat brain (rNa(v)1.2a) and skeletal muscle (rNa(v)1.4) channels using binding studies revealed commonality but also substantial differences, which were used to design a specific activator, Css4(F14A/E15A/E28R), of rNa(v)1.4 expressed in Xenopus oocytes. The therapeutic potential of Css4(F14A/E15A/E28R) was tested using an rNa(v)1.4 mutant carrying the same mutation present in the genetic disorder hypokalemic periodic paralysis. The activator restored the impaired gating properties of the mutant channel expressed in oocytes, thus offering a tentative new means for treatment of neuromuscular disorders with reduced muscle excitability. Mutant double cycle analysis employing toxin residues involved in the construction of Css4(F14A/E15A/E28R) and residues whose equivalents in the rat brain channel rNa(v)1.2a were shown to affect Css4 binding revealed significant coupling energy (>1.3 kcal/mol) between F14A and E592A at Domain-2/voltage sensor segments 1-2 (D2/S1-S2), R27Q and E1251N at D3/SS2-S6, and E28R with both E650A at D2/S3-S4 and E1251N at D3/SS2-S6. These results show that despite the differences in interactions with the rat brain and skeletal muscle Na(v)s, Css4 recognizes a similar region on both channel subtypes. Moreover, our data indicate that the S3-S4 loop of the voltage sensor module in Domain-2 is in very close proximity to the SS2-S6 segment of the pore module of Domain-3 in rNa(v)1.4. This is the first experimental evidence that the inter-domain spatial organization of mammalian Na(v)s resembles that of voltage-gated potassium channels.

  17. Aroma-Active Compounds in Bartlett Pears and Their Changes during the Manufacturing Process of Bartlett Pear Brandy.

    Science.gov (United States)

    Zierer, Bianca; Schieberle, Peter; Granvogl, Michael

    2016-12-21

    Application of aroma extract dilution analysis to Bartlett pears and the fermented mash produced thereof revealed 24 and 34 aroma-active compounds in the flavor dilution (FD) factor range between 8 and 8192. Twenty-eight compounds, which have not been described before in Bartlett pears or in fermented pear mash, were identified. While ethyl (E,Z)-2,4-decadienoate (pear-like, metallic odor impression), hexyl acetate (green, fruity), and acetic acid (vinegar-like) showed the highest concentrations in Bartlett pears, ethanol (ethanolic), acetic acid, 3-methyl-1-butanol (malty), 1-hexanol (grassy, marzipan-like), (S)-2- and 3-methylbutanoic acid (sweaty), and 2-phenylethanol (flowery, honey-like) were present at the highest amounts in the fermented mash. The key aroma compounds were quantitated in each pear brandy production step (pears, fermented mash, distillate, and aged distillate) by stable isotope dilution analysis showing a clear influence of each step on the overall aroma of the spirit and, consequently, revealing clearly changing concentrations (e.g., of ethyl (S)-2-methylbutanoate, (E)-β-damascenone, ethyl (E,Z)-2,4-decadienoate, and ethyl (E,E)-2,4-decadienoate) and different aroma perceptions during the manufacturing process. In addition, the concentrations of the so-called "pear esters" ethyl (E,Z)-2,4-decadienoate and ethyl (E,E)-2,4-decadienoate were determined in 6 different pear varieties (Abate Fetel, Anjou, Bartlett, Forelle, Kaiser Alexander, and Packham's Triumph) clearly demonstrating the aroma potential of the variety Bartlett, which is mostly used for brandy production due to the high amounts of both esters eliciting a typical pear-like odor impression.

  18. Humanizing Architecture

    DEFF Research Database (Denmark)

    Toft, Tanya Søndergaard

    2015-01-01

    The article proposes the urban digital gallery as an opportunity to explore the relationship between ‘human’ and ‘technology,’ through the programming of media architecture. It takes a curatorial perspective when proposing an ontological shift from considering media facades as visual spectacles...... agency and a sense of being by way of dematerializing architecture. This is achieved by way of programming the symbolic to provide new emotional realizations and situations of enlightenment in the public audience. This reflects a greater potential to humanize the digital in media architecture....

  19. 云制造环境下活动驱动的工业设计电子服务系统%Activity driven industrial design E-service system in cloud manufacturing

    Institute of Scientific and Technical Information of China (English)

    程时伟; 刘肖健

    2012-01-01

    To adapt to network cloud manufacturing mode oriented to service, and to improve industrial design level for medium and small enterprises, E-service system architecture for industrial design in cloud manufacturing was proposed. The activity theory was used to model the industrial design E-service, and the key elements such as subjects, objects and tools were extracted, thus the activity structure of E-service system and the analysis hierarchy were constructed. The functions of cloud manufacturing environment on industrial design E-service were analyzed, and sub-systems of service generation, service collaboration, service distribution and service consumption were set up. Besides, network based key technologies of design service resource integration and user experience enhanced human computer interaction were described. An industrial design E-service application system for lamp products was presented, and the design quality and work efficiency was improved through the system's operation in related enterprises.%为适应面向服务的网络化云制造模式,提升中小企业工业设计水平,提出云制造环境下的工业设计电子服务系统架构。基于活动理论对工业设计电子服务进行建模,提取活动主体、客体、工具等要素,建立电子服务系统的活动结构和层次分析框架。分析云制造环境对工业设计电子服务的作用机制,建立服务生产、协作、分配和消费子系统,并阐述了基于网络的设计服务资源集成和增强用户体验的人机交互等关键实现技术。给出一个面向灯具产品的工业设计电子服务应用系统实例,通过在相关企业运行,表明其能有效提高产品设计质量和设计工作效率。

  20. Analysis of trabecular bone architectural changes induced by osteoarthritis in rabbit femur using 3D active shape model and digital topology

    Science.gov (United States)

    Saha, P. K.; Rajapakse, C. S.; Williams, D. S.; Duong, L.; Coimbra, A.

    2007-03-01

    Osteoarthritis (OA) is the most common chronic joint disease, which causes the cartilage between the bone joints to wear away, leading to pain and stiffness. Currently, progression of OA is monitored by measuring joint space width using x-ray or cartilage volume using MRI. However, OA affects all periarticular tissues, including cartilage and bone. It has been shown previously that in animal models of OA, trabecular bone (TB) architecture is particularly affected. Furthermore, relative changes in architecture are dependent on the depth of the TB region with respect to the bone surface and main direction of load on the bone. The purpose of this study was to develop a new method for accurately evaluating 3D architectural changes induced by OA in TB. Determining the TB test domain that represents the same anatomic region across different animals is crucial for studying disease etiology, progression and response to therapy. It also represents a major technical challenge in analyzing architectural changes. Here, we solve this problem using a new active shape model (ASM)-based approach. A new and effective semi-automatic landmark selection approach has been developed for rabbit distal femur surface that can easily be adopted for many other anatomical regions. It has been observed that, on average, a trained operator can complete the user interaction part of landmark specification process in less than 15 minutes for each bone data set. Digital topological analysis and fuzzy distance transform derived parameters are used for quantifying TB architecture. The method has been applied on micro-CT data of excised rabbit femur joints from anterior cruciate ligament transected (ACLT) (n = 6) and sham (n = 9) operated groups collected at two and two-to-eight week post-surgery, respectively. An ASM of the rabbit right distal femur has been generated from the sham group micro-CT data. The results suggest that, in conjunction with ASM, digital topological parameters are suitable for

  1. Architectural Engineers

    DEFF Research Database (Denmark)

    Petersen, Rikke Premer

    engineering is addresses from two perspectives – as an educational response and an occupational constellation. Architecture and engineering are two of the traditional design professions and they frequently meet in the occupational setting, but at educational institutions they remain largely estranged......The design professions have always been an amorphous phenomena difficult to merge under one label. New constellations continually emerge, questioning, stretching, and reconfiguring the understanding of design and the professional practices linked to it. In this paper the idea of architectural....... The paper builds on a multi-sited study of an architectural engineering program at the Technical University of Denmark and an architectural engineering team within an international engineering consultancy based on Denmark. They are both responding to new tendencies within the building industry where...

  2. Architectural Mealscapes

    DEFF Research Database (Denmark)

    Tvedebrink, Tenna Doktor Olsen; Fisker, Anna Marie; Kirkegaard, Poul Henning

    2012-01-01

    the German architect Gottfried Semper developed a theory on the “four elements of Architecture” tracing the origin of architecture back to the rise of the early human settlement and the creation of fire. With the notion ‘hearth’ as the first motive in architecture and the definition of three enclosing...... motives; mounding, enclosure and roof, Semper linked the cultural and social values of the primordial fireplace with the order and shape of architecture. He claimed that any building ever made was nothing but a variation of the first primitive shelters erected around the fireplace, and that the three...... enclosing motives existed only as defenders of the “sacred flame”. In that way Semper developed the idea that any architectural scenery can be described, analyzed and explained by understanding the contextual, symbolic and social values of how the four basic motives of hearth, mounding, enclosure, and roof...

  3. Systemic Architecture

    DEFF Research Database (Denmark)

    Poletto, Marco; Pasquero, Claudia

    2012-01-01

    design protocols developed to describe the city as a territory of self-organization. Collecting together nearly a decade of design experiments by the authors and their practice, ecoLogicStudio, the book discusses key disciplinary definitions such as ecologic urbanism, algorithmic architecture, bottom......-up or tactical design, behavioural space and the boundary of the natural and the artificial realms within the city and architecture. A new kind of "real-time world-city" is illustrated in the form of an operational design manual for the assemblage of proto-architectures, the incubation of proto......-gardens and the coding of proto-interfaces. These prototypes of machinic architecture materialize as synthetic hybrids embedded with biological life (proto-gardens), computational power, behavioural responsiveness (cyber-gardens), spatial articulation (coMachines and fibrous structures), remote sensing (FUNclouds...

  4. Advanced customization in architectural design and construction

    CERN Document Server

    Naboni, Roberto

    2015-01-01

    This book presents the state of the art in advanced customization within the sector of architectural design and construction, explaining important new technologies that are boosting design, product and process innovation and identifying the challenges to be confronted as we move toward a mass customization construction industry. Advanced machinery and software integration are discussed, as well as an overview of the manufacturing techniques offered through digital methods that are acquiring particular significance within the field of digital architecture. CNC machining, Robotic Fabrication, and Additive Manufacturing processes are all clearly explained, highlighting their ability to produce personalized architectural forms and unique construction components. Cutting-edge case studies in digitally fabricated architectural realizations are described and, looking towards the future, a new model of 100% customized architecture for design and construction is presented. The book is an excellent guide to the profoun...

  5. The Connotation of Digital Manufacturing Science and Its Expectation

    Institute of Scientific and Technical Information of China (English)

    ZHOU Zude; LIU Quan

    2006-01-01

    After reviewing the phylogeny of manufacturing activities and manufacturing science and summarizing the application actuality of digital manufacturing(DM) technologies in manufacturing, the theory supporting system of digital manufacturing science (DMS) were deeply researched, including calculation manufacturing science and manufacturing informatics, bionics mechanics, manufacturing intelligent science and technical management science and so on. Then the connation of digital manufacturing technologies were dissertated, includes the digital technology set of product life cycle, the digital manufacturing resources technology set, the manufacturing information technology set and technology characterizations of digital products. The developing directions of DMS in future were put forward at last.

  6. Manufacturing technology

    Energy Technology Data Exchange (ETDEWEB)

    Leonard, J.A.; Floyd, H.L.; Goetsch, B.; Doran, L. [eds.

    1993-08-01

    This bulletin depicts current research on manufacturing technology at Sandia laboratories. An automated, adaptive process removes grit overspray from jet engine turbine blades. Advanced electronic ceramics are chemically prepared from solution for use in high- voltage varistors. Selective laser sintering automates wax casting pattern fabrication. Numerical modeling improves performance of photoresist stripper (simulation on Cray supercomputer reveals path to uniform plasma). And mathematical models help make dream of low- cost ceramic composites come true.

  7. An Active Networks Architecture Based on Mobile Agent%一种基于移动Agent的主动网络体系结构

    Institute of Scientific and Technical Information of China (English)

    张君雁; 闵帆; 杨国纬

    2003-01-01

    This paper proposes an active networks architecture which supports both integrated and discrete operationmodel based on mobile Agent technology. Mobile Agent is the component for customized function transferring, activenode provides software application layer, and Agent server processes mobile Agent specific customization. For devel-opment and deployment of specific application protocol, this paper also proposes an abstract protocol framework and aprotocol loading mechanism to enhance network performance.

  8. ANALYSIS OF THE KEY ACTIVITIES OF THE LIFE CYCLE OF KNOWLEDGE MANAGEMENT IN THE UNIVERSITY AND DEVELOPMENT OF THE CONCEPTUAL ARCHITECTURE OF THE KNOWLEDGE MANAGEMENT SYSTEM

    Directory of Open Access Journals (Sweden)

    Eugene N. Tcheremsina

    2013-01-01

    Full Text Available This article gives an analysis of the key activities of the life cycle of knowledge management in terms of the features of knowledge management in higher education. Based on the analysis we propose the model of the conceptual architecture of virtual knowledge-space of a university. The proposed model is the basis for the development of kernel intercollegiate virtual knowledge-space, based on cloud technology. 

  9. Architectural geometry

    KAUST Repository

    Pottmann, Helmut

    2014-11-26

    Around 2005 it became apparent in the geometry processing community that freeform architecture contains many problems of a geometric nature to be solved, and many opportunities for optimization which however require geometric understanding. This area of research, which has been called architectural geometry, meanwhile contains a great wealth of individual contributions which are relevant in various fields. For mathematicians, the relation to discrete differential geometry is significant, in particular the integrable system viewpoint. Besides, new application contexts have become available for quite some old-established concepts. Regarding graphics and geometry processing, architectural geometry yields interesting new questions but also new objects, e.g. replacing meshes by other combinatorial arrangements. Numerical optimization plays a major role but in itself would be powerless without geometric understanding. Summing up, architectural geometry has become a rewarding field of study. We here survey the main directions which have been pursued, we show real projects where geometric considerations have played a role, and we outline open problems which we think are significant for the future development of both theory and practice of architectural geometry.

  10. Transfer of manufacturing units

    DEFF Research Database (Denmark)

    Madsen, Erik Skov; Riis, Jens Ove; Sørensen, Brian Vejrum

    2008-01-01

    The ongoing and unfolding relocation of activities is one of the major trends, that calls for attention in the domain of operations management. In particular, prescriptive models outlining: stages of the process, where to locate, and how to establish the new facilities have been studied, while th...... and dilemmas to be addressed when transferring manufacturing units....

  11. Architectural Anthropology

    DEFF Research Database (Denmark)

    Stender, Marie

    Architecture and anthropology have always had a common focus on dwelling, housing, urban life and spatial organisation. Current developments in both disciplines make it even more relevant to explore their boundaries and overlaps. Architects are inspired by anthropological insights and methods......, while recent material and spatial turns in anthropology have also brought an increasing interest in design, architecture and the built environment. Understanding the relationship between the social and the physical is at the heart of both disciplines, and they can obviously benefit from further...... collaboration: How can qualitative anthropological approaches contribute to contemporary architecture? And just as importantly: What can anthropologists learn from architects’ understanding of spatial and material surroundings? Recent theoretical developments in anthropology stress the role of materials...

  12. Multithreading architecture

    CERN Document Server

    Nemirovsky, Mario

    2013-01-01

    Multithreaded architectures now appear across the entire range of computing devices, from the highest-performing general purpose devices to low-end embedded processors. Multithreading enables a processor core to more effectively utilize its computational resources, as a stall in one thread need not cause execution resources to be idle. This enables the computer architect to maximize performance within area constraints, power constraints, or energy constraints. However, the architectural options for the processor designer or architect looking to implement multithreading are quite extensive and

  13. Architectural Anthropology

    DEFF Research Database (Denmark)

    Stender, Marie

    and other spaces that architects are preoccupied with. On the other hand, the distinction between architecture and design is not merely one of scale. Design and architecture represent – at least in Denmark – also quite different disciplinary traditions and methods. Where designers develop prototypes......, architects tend to work with models and plans that are not easily understood by lay people. Further, many architects are themselves sceptical towards notions of user-involvement and collaborative design. They fear that the imagination of citizens and users is restricted to what they are already familiar with...

  14. Paneling architectural freeform surfaces

    KAUST Repository

    Eigensatz, Michael

    2010-07-25

    The emergence of large-scale freeform shapes in architecture poses big challenges to the fabrication of such structures. A key problem is the approximation of the design surface by a union of patches, so-called panels, that can be manufactured with a selected technology at reasonable cost, while meeting the design intent and achieving the desired aesthetic quality of panel layout and surface smoothness. The production of curved panels is mostly based on molds. Since the cost of mold fabrication often dominates the panel cost, there is strong incentive to use the same mold for multiple panels. We cast the major practical requirements for architectural surface paneling, including mold reuse, into a global optimization framework that interleaves discrete and continuous optimization steps to minimize production cost while meeting user-specified quality constraints. The search space for optimization is mainly generated through controlled deviation from the design surface and tolerances on positional and normal continuity between neighboring panels. A novel 6-dimensional metric space allows us to quickly compute approximate inter-panel distances, which dramatically improves the performance of the optimization and enables the handling of complex arrangements with thousands of panels. The practical relevance of our system is demonstrated by paneling solutions for real, cutting-edge architectural freeform design projects.

  15. Paneling architectural freeform surfaces

    KAUST Repository

    Eigensatz, Michael

    2010-07-26

    The emergence of large-scale freeform shapes in architecture poses big challenges to the fabrication of such structures. A key problem is the approximation of the design surface by a union of patches, socalled panels, that can be manufactured with a selected technology at reasonable cost, while meeting the design intent and achieving the desired aesthetic quality of panel layout and surface smoothness. The production of curved panels is mostly based on molds. Since the cost of mold fabrication often dominates the panel cost, there is strong incentive to use the same mold for multiple panels. We cast the major practical requirements for architectural surface paneling, including mold reuse, into a global optimization framework that interleaves discrete and continuous optimization steps to minimize production cost while meeting user-specified quality constraints. The search space for optimization is mainly generated through controlled deviation from the design surface and tolerances on positional and normal continuity between neighboring panels. A novel 6-dimensional metric space allows us to quickly compute approximate inter-panel distances, which dramatically improves the performance of the optimization and enables the handling of complex arrangements with thousands of panels. The practical relevance of our system is demonstrated by paneling solutions for real, cutting-edge architectural freeform design projects. © 2010 ACM.

  16. Research on an Agile Manufacturing Information System

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    With the more intense competition in the worldwide market, the agile virtual enterprise (AVE) will become a new organization form of manufacturing enterprise. To support the new rela tionship, an agile manufacturing information system (AMIS) is described in this paper which serves to assist the virtual enterprise to manage and control information flow among collaborating partners. Based on the requirement analysis of virtual information system, the architecture, functions, features and execution scheme of AMIS are discussed in detail.

  17. Research on Evaluation and Management of Networked Manufacturing Resources Based on WUXIASP

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    The data models and description of manufacturing resources are discussed for realizing distributed networked manufacturing and the multi-goal evaluating model is put forward. The factors and process in networked manufacturing resources evaluating are given, and the service function and the system architecture of WUXIASP is set up. It is useful to actualize area networked manufacture.

  18. Architectural Tops

    Science.gov (United States)

    Mahoney, Ellen

    2010-01-01

    The development of the skyscraper is an American story that combines architectural history, economic power, and technological achievement. Each city in the United States can be identified by the profile of its buildings. The design of the tops of skyscrapers was the inspiration for the students in the author's high-school ceramic class to develop…

  19. Religious Architecture

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    The main religions of ancient China were Buddhism,Taoism and Islam, of which Buddhism was the most widespread. As a result, Buddhist temples and towers are found all over China, and have become important components of the country's ancient architecture.

  20. Textile Architecture

    DEFF Research Database (Denmark)

    Heimdal, Elisabeth Jacobsen

    2010-01-01

    Textiles can be used as building skins, adding new aesthetic and functional qualities to architecture. Just like we as humans can put on a coat, buildings can also get dressed. Depending on our mood, or on the weather, we can change coat, and so can the building. But the idea of using textiles...

  1. Additive Manufacturing of Aerospace Propulsion Components

    Science.gov (United States)

    Misra, Ajay K.; Grady, Joseph E.; Carter, Robert

    2015-01-01

    The presentation will provide an overview of ongoing activities on additive manufacturing of aerospace propulsion components, which included rocket propulsion and gas turbine engines. Future opportunities on additive manufacturing of hybrid electric propulsion components will be discussed.

  2. Manufacturing strategy issues in selected Indian manufacturing industry

    Directory of Open Access Journals (Sweden)

    Mahender Singh

    2013-03-01

    Full Text Available This paper presents some findings of Indian manufacturing sectors viz. automobile (especially two-wheeler, tractor and general manufacturing industry. Various manufacturing strategy issues such as competitive priorities, improvement activities, and performance measures, have been identified and assessed in Indian context. Sector wise comparison of competitive priorities, improvement activities i.e. advanced manufacturing technology (AMT, integrated information systems (IIS, and advanced management systems (AMS, and performance measure, is provided. Our results showed that most of the Indian companies are still emphasizing on quality. However, automobile sector has set to compete globally with high innovation rate, faster new product development, and continuous improvement. It is also observed that Indian companies are investing more in AMS as compared to IIS and AMT. Manufacturing competence index is also computed for each sector.

  3. Principles of landscape architecture

    NARCIS (Netherlands)

    Nijhuis, S.

    2013-01-01

    The Department of Urbanism at the Faculty of Architecture and Built Environment, TU Delft considers urbanism as a planning and design oriented activity towards urban and rural landscapes. It aims to enhance, restore or create landscapes from a perspective of sustainable development, so as to guide,

  4. 石煤渣在制造建筑轻骨料中的应用研究%Application of Stone Coal Cinder in Manufacturing Architecture for Lightweight Aggregate

    Institute of Scientific and Technical Information of China (English)

    冯永

    2013-01-01

    以石煤渣作原料来制造建筑轻骨料,所制造的轻骨料密度小、保温性好、抗震性好,应用于高层及大跨度建筑轻骨料混凝土中效果很好。通过实验详细分析了石煤渣在制造轻骨料中的反应,论述了石煤渣掺量与粘结剂对所制造的建筑轻骨料性能及工艺的影响。%Taking the stone coal cinder as raw materials to manufacture building lightweight aggregate, made of lightweight aggregate small density, good insulation resistance, good shock resistance, used in high and large span buildings in lightweight aggregate concrete effect is very good. The author detailed analysis through the experiment of stone coal cinder in manufacturing lightweight aggregate reaction, this paper discusses the dosage of stone coal cinder and binder for the manufacture of building performance of lightweight aggregate and the influence of the process.

  5. Nanorobot architecture for medical target identification

    Science.gov (United States)

    Cavalcanti, Adriano; Shirinzadeh, Bijan; Freitas, Robert A., Jr.; Hogg, Tad

    2008-01-01

    This work has an innovative approach for the development of nanorobots with sensors for medicine. The nanorobots operate in a virtual environment comparing random, thermal and chemical control techniques. The nanorobot architecture model has nanobioelectronics as the basis for manufacturing integrated system devices with embedded nanobiosensors and actuators, which facilitates its application for medical target identification and drug delivery. The nanorobot interaction with the described workspace shows how time actuation is improved based on sensor capabilities. Therefore, our work addresses the control and the architecture design for developing practical molecular machines. Advances in nanotechnology are enabling manufacturing nanosensors and actuators through nanobioelectronics and biologically inspired devices. Analysis of integrated system modeling is one important aspect for supporting nanotechnology in the fast development towards one of the most challenging new fields of science: molecular machines. The use of 3D simulation can provide interactive tools for addressing nanorobot choices on sensing, hardware architecture design, manufacturing approaches, and control methodology investigation.

  6. Nanorobot architecture for medical target identification

    Energy Technology Data Exchange (ETDEWEB)

    Cavalcanti, Adriano [CAN Center for Automation in Nanobiotech, Melbourne VIC 3168 (Australia); Shirinzadeh, Bijan [Robotics and Mechatronics Research Laboratory, Department of Mechanical Engineering, Monash University, Clayton, Melbourne VIC 3800 (Australia); Freita, Robert A Jr [Institute for Molecular Manufacturing, Pilot Hill, CA 95664 (United States); Hogg, Tad [Hewlett-Packard Laboratories, Palo Alto, CA 94304 (United States)

    2008-01-09

    This work has an innovative approach for the development of nanorobots with sensors for medicine. The nanorobots operate in a virtual environment comparing random, thermal and chemical control techniques. The nanorobot architecture model has nanobioelectronics as the basis for manufacturing integrated system devices with embedded nanobiosensors and actuators, which facilitates its application for medical target identification and drug delivery. The nanorobot interaction with the described workspace shows how time actuation is improved based on sensor capabilities. Therefore, our work addresses the control and the architecture design for developing practical molecular machines. Advances in nanotechnology are enabling manufacturing nanosensors and actuators through nanobioelectronics and biologically inspired devices. Analysis of integrated system modeling is one important aspect for supporting nanotechnology in the fast development towards one of the most challenging new fields of science: molecular machines. The use of 3D simulation can provide interactive tools for addressing nanorobot choices on sensing, hardware architecture design, manufacturing approaches, and control methodology investigation.

  7. Reframing information architecture

    CERN Document Server

    Resmini, Andrea

    2014-01-01

    Information architecture has changed dramatically since the mid-1990s and earlier conceptions of the world and the internet being different and separate have given way to a much more complex scenario in the present day. In the post-digital world that we now inhabit the digital and the physical blend easily and our activities and usage of information takes place through multiple contexts and via multiple devices and unstable, emergent choreographies. Information architecture now is steadily growing into a channel- or medium-specific multi-disciplinary framework, with contributions coming from a

  8. Developing a System Architecture for Holonic Shop Floor Control

    DEFF Research Database (Denmark)

    Sørensen, Christian; Langer, Gilad; Alting, Leo

    1998-01-01

    This paper describes the results of research regarding the emerging theory of Holonic Manufacturing Systems. This theory and in particular its corresponding reference architecture serves as the basis for the development of a system-architecture for shop floor control systems in a multi-cellular c......This paper describes the results of research regarding the emerging theory of Holonic Manufacturing Systems. This theory and in particular its corresponding reference architecture serves as the basis for the development of a system-architecture for shop floor control systems in a multi...

  9. Architecture Knowledge Management: Challenges, Approaches, and Tools

    Energy Technology Data Exchange (ETDEWEB)

    Babar, Muhammad A.; Gorton, Ian

    2007-08-01

    Capturing the technical knowledge, contextual information, and rationale surrounding the design decisions underpinning system architectures can greatly improve the software development process. If not managed, this critical knowledge is implicitly embedded in the architecture, becoming tacit knowledge which erodes as personnel on the project change. Moreover, the unavailability of architecture knowledge precludes organizations from growing their architectural capabilities. In this tutorial, we highlight the benefits and challenges in managing software architecture knowledge. We discuss various approaches to characterize architecture knowledge based on the requirements of a particular domain. We describe various concepts and approaches to manage the architecture knowledge from both management and technical perspectives. We also demonstrate the utility of captured knowledge to support software architecture activities with a case study covering the use of architecture knowledge management techniques and tools in an industrial project.

  10. MUF architecture /art London

    DEFF Research Database (Denmark)

    Svenningsen Kajita, Heidi

    2009-01-01

    Om MUF architecture samt interview med Liza Fior og Katherine Clarke, partnere i muf architecture/art......Om MUF architecture samt interview med Liza Fior og Katherine Clarke, partnere i muf architecture/art...

  11. Altered architecture and enhanced drought tolerance in rice via the down-regulation of indole-3-acetic acid by TLD1/OsGH3.13 activation.

    Science.gov (United States)

    Zhang, Sheng-Wei; Li, Chen-Hui; Cao, Jia; Zhang, Yong-Cun; Zhang, Su-Qiao; Xia, Yu-Feng; Sun, Da-Ye; Sun, Ying

    2009-12-01

    Plant architecture is determined by genetic and developmental programs as well as by environmental factors. Sessile plants have evolved a subtle adaptive mechanism that allows them to alter their growth and development during periods of stress. Phytohormones play a central role in this process; however, the molecules responsible for integrating growth- and stress-related signals are unknown. Here, we report a gain-of-function rice (Oryza sativa) mutant, tld1-D, characterized by (and named for) an increased number of tillers, enlarged leaf angles, and dwarfism. TLD1 is a rice GH3.13 gene that encodes indole-3-acetic acid (IAA)-amido synthetase, which is suppressed in aboveground tissues under normal conditions but which is dramatically induced by drought stress. The activation of TLD1 reduced the IAA maxima at the lamina joint, shoot base, and nodes, resulting in subsequent alterations in plant architecture and tissue patterning but enhancing drought tolerance. Accordingly, the decreased level of free IAA in tld1-D due to the conjugation of IAA with amino acids greatly facilitated the accumulation of late-embryogenesis abundant mRNA compared with the wild type. The direct regulation of such drought-inducible genes by changes in the concentration of IAA provides a model for changes in plant architecture via the process of drought adaptation, which occurs frequently in nature.

  12. Tectonic Thinking in Contemporary Industrialized Architecture

    OpenAIRE

    Dell, Anne

    2013-01-01

    This paper argues for a new critical approach to the ways architectural design strategies are developing. Contemporary construction industry appears to evolve into highly specialized and optimized processes driven by industrialized manufacturing, therefore the role of the architect and the understanding of the architectural design process ought to be revised. The paper is based on the following underlying hypothesis: ‘Tectonic thinking – defined as a central attention towards the nature, the ...

  13. Architectural Theatricality

    DEFF Research Database (Denmark)

    Tvedebrink, Tenna Doktor Olsen

    putting an emphasis on architecture as unified scenery guided by the four motives hearth, enclosure, dressing and context. This theoretical framework draws on the Gastronomic Analogy put forth by James Fergusson in 1862 and an interpretation of the writings of the 19th century architect Gottfried Semper...... with the material appearance of objects, but also the imaginary world of dreams and memories which are concealed with the communicative significance of intentions when designing the future super hospitals....

  14. Architectural Theatricality

    DEFF Research Database (Denmark)

    Tvedebrink, Tenna Doktor Olsen; Fisker, Anna Marie; Kirkegaard, Poul Henning

    2013-01-01

    is known for his writings on theatricality, understood as a holistic design approach emphasizing the contextual, cultural, ritual and social meanings rooted in architecture. Relative hereto, the International Food Design Society recently argued, in a similar holistic manner, that the methodology used......’ is an overlooked element in hospital eating environments today, and further point at how Semper’s discourse on theatricality can be used to add a more nuanced perspective to future hospitality studies....

  15. E3 Sustainable Manufacturing Curriculum

    Science.gov (United States)

    A short E3 course containing three modules on Environmental Sustainability; Lean Manufacturing and Pollution Prevention; and Energy and Carbon. Each module includes slides, a facilitator's guide with handouts, activities, quizzes, and facilitator's notes.

  16. Developing Materials Processing to Performance Modeling Capabilities and the Need for Exascale Computing Architectures (and Beyond)

    Energy Technology Data Exchange (ETDEWEB)

    Schraad, Mark William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Physics and Engineering Models; Luscher, Darby Jon [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Advanced Simulation and Computing

    2016-09-06

    Additive Manufacturing techniques are presenting the Department of Energy and the NNSA Laboratories with new opportunities to consider novel component production and repair processes, and to manufacture materials with tailored response and optimized performance characteristics. Additive Manufacturing technologies already are being applied to primary NNSA mission areas, including Nuclear Weapons. These mission areas are adapting to these new manufacturing methods, because of potential advantages, such as smaller manufacturing footprints, reduced needs for specialized tooling, an ability to embed sensing, novel part repair options, an ability to accommodate complex geometries, and lighter weight materials. To realize the full potential of Additive Manufacturing as a game-changing technology for the NNSA’s national security missions; however, significant progress must be made in several key technical areas. In addition to advances in engineering design, process optimization and automation, and accelerated feedstock design and manufacture, significant progress must be made in modeling and simulation. First and foremost, a more mature understanding of the process-structure-property-performance relationships must be developed. Because Additive Manufacturing processes change the nature of a material’s structure below the engineering scale, new models are required to predict materials response across the spectrum of relevant length scales, from the atomistic to the continuum. New diagnostics will be required to characterize materials response across these scales. And not just models, but advanced algorithms, next-generation codes, and advanced computer architectures will be required to complement the associated modeling activities. Based on preliminary work in each of these areas, a strong argument for the need for Exascale computing architectures can be made, if a legitimate predictive capability is to be developed.

  17. Additive manufacturing of wet-spun polymeric scaffolds for bone tissue engineering.

    Science.gov (United States)

    Puppi, Dario; Mota, Carlos; Gazzarri, Matteo; Dinucci, Dinuccio; Gloria, Antonio; Myrzabekova, Mairam; Ambrosio, Luigi; Chiellini, Federica

    2012-12-01

    An Additive Manufacturing technique for the fabrication of three-dimensional polymeric scaffolds, based on wet-spinning of poly(ε-caprolactone) (PCL) or PCL/hydroxyapatite (HA) solutions, was developed. The processing conditions to fabricate scaffolds with a layer-by-layer approach were optimized by studying their influence on fibres morphology and alignment. Two different scaffold architectures were designed and fabricated by tuning inter-fibre distance and fibres staggering. The developed scaffolds showed good reproducibility of the internal architecture characterized by highly porous, aligned fibres with an average diameter in the range 200-250 μm. Mechanical characterization showed that the architecture and HA loading influenced the scaffold compressive modulus and strength. Cell culture experiments employing MC3T3-E1 preosteoblast cell line showed good cell adhesion, proliferation, alkaline phosphatase activity and bone mineralization on the developed scaffolds.

  18. Drawing Architecture Theory on the City

    NARCIS (Netherlands)

    Altürk, E.

    2009-01-01

    This study is about architectural drawings. I especially address how drawings operate in architecture theory, and stress a particular role that they play in facilitating critique and speculation as theoretical activities. In this sense, I dwell on the capacity of architectural drawing not only as re

  19. Multi-agent for manufacturing systems optimization

    Science.gov (United States)

    Ciortea, E. M.; Tulbure, A.; Huţanu, C.-tin

    2016-08-01

    The paper is meant to be a dynamic approach to optimize manufacturing systems based on multi-agent systems. Multi-agent systems are semiautonomous decision makers and cooperate to optimize the manufacturing process. Increasing production the capacity is achieved by developing, implementing efficient and effective systems from control based on current manufacturing process. The model multi-agent proposed in this paper is based on communication between agents who, based on their mechanisms drive to autonomous decision making. Methods based on multi-agent programming are applied between flexible manufacturing processes and cooperation with agents. Based on multi-agent technology and architecture of intelligent manufacturing can lead to development of strategies for control and optimization of scheduled production resulting from the simulation.

  20. Virtual manufacturing in reality

    Science.gov (United States)

    Papstel, Jyri; Saks, Alo

    2000-10-01

    SMEs play an important role in manufacturing industry. But from time to time there is a shortage in resources to complete the particular order in time. Number of systems is introduced to produce digital information in order to support product and process development activities. Main problem is lack of opportunity for direct data transition within design system modules when needed temporary extension of design capacity (virtuality) or to implement integrated concurrent product development principles. The planning experience in the field is weakly used as well. The concept of virtual manufacturing is a supporting idea to solve this problem. At the same time a number of practical problems should be solved like information conformity, data transfer, unified technological concepts acceptation etc. In the present paper the proposed ways to solve the practical problems of virtual manufacturing are described. General objective is to introduce the knowledge-based CAPP system as missing module for Virtual Manufacturing in the selected product domain. Surface-centered planning concept based on STEP- based modeling principles, and knowledge-based process planning methodology will be used to gain the objectives. As a result the planning module supplied by design data with direct access, and supporting advising environment is expected. Mould producing SME would be as test basis.

  1. THE SCENE OF ARCHITECTURAL SPACE IN THE CONTEX PRESSIVE BEING OF ARCHITECTURAL SPACE

    Directory of Open Access Journals (Sweden)

    Elena E. BIRYUKOVA

    2015-01-01

    Full Text Available The aesthetic aspects of the existence of architectural space is closely related to its scene. The scene of architectural objects and all the architectural space allow enables the existence and active external expression of its non-use component, abstract spiritual meanings, ideas and images. The purpose of this study is the aesthetic and philosophical analysis of the shape of architectural space. The research problem is the search for the relationship between the scene of the architectural space and its existence as the outer presentation of spiritual meanings. Under the scene of architectural space we mean to its expressive exterior shell that is available to the perception of the senses. Architectural space is a certain visibility. This space by which can act spiritual aspects of the human content of architecture. The architectural scene is not only the look of the architectural object or element of architectural space, but and architectural appearance (face of the people. The architectural scene is built in accordance with the needs of the inner world of man and contains the image of the person in the material form. It is also the external scene of the architectural environment for human been and appearance of the individual life. Therefore, the scene of architecture is concrete space. National, social, cultural identity finds expression through the scene of its architectural space. 

  2. 主动网络安全结构模型设计%Design of Secure System Architecture Model for Active Network

    Institute of Scientific and Technical Information of China (English)

    夏正友; 张世永

    2002-01-01

    介绍了主动网络安全系统的假设模型和威胁模型.基于上述模型和主动网络的安全需要提出了一种安全系统结构模型.该安全模型包括授权、认证、完整性检查和加密等.使用加密和数字签名方法来保护主动网络报文的完整性,使用授权和政策来阻止非法访问以及主动节点的资源请求和行为.%In this paper, the assumption model and the threat model of active network security system are introduced. A secure system architecture model based on these models and security requirement is presented. Definition of secure system architecture model includes authentication, authorization, integrity and encryption. To protect the integrity of the contents of active packet, the encryption and the digital signatures can be employed and the authorization mechanisms or policies are defined and enforced to provide controlled access to the active node resources.

  3. Association between the activation of MCH and orexin immunorective neurons and REM sleep architecture during REM rebound after a three day long REM deprivation.

    Science.gov (United States)

    Kitka, Tamas; Adori, Csaba; Katai, Zita; Vas, Szilvia; Molnar, Eszter; Papp, Rege S; Toth, Zsuzsanna E; Bagdy, Gyorgy

    2011-10-01

    Rapid eye movement (REM) sleep rebound following REM deprivation using the platform-on-water method is characterized by increased time spent in REM sleep and activation of melanin-concentrating hormone (MCH) expressing neurons. Orexinergic neurons discharge reciprocally to MCH-ergic neurons across the sleep-wake cycle. However, the relation between REM architecture and the aforementioned neuropeptides remained unclear. MCH-ergic neurons can be divided into two subpopulations regarding their cocaine- and amphetamine-regulated transcript (CART) immunoreactivity, and among them the activation of CART-immunoreactive subpopulation is higher during the REM rebound. However, the possible role of stress in this association has not been elucidated. Our aims were to analyze the relationship between the architecture of REM rebound and the activation of hypothalamic MCH-ergic and orexinergic neurons. We also intended to separate the effect of stress and REM deprivation on the subsequent activation of subpopulations of MCH-ergic neurons. In order to detect neuronal activity, we performed MCH/cFos and orexin/cFos double immunohistochemistry on home cage, sleep deprived and sleep-rebound rats using the platform-on-water method with small and large (stress control) platforms. Furthermore, REM architecture was analyzed and a triple MCH/CART/cFos immunohistochemistry was also performed on the rebound groups in the same animals. We found that the activity of MCH- and orexin-immunoreactive neurons during REM rebound was positively and negatively correlated with the number of REM bouts, respectively. A negative reciprocal correlation was also found between the activation of MCH- and orexin-immunoreactive neurons during REM rebound. Furthermore, difference between the activation of CART-immunoreactive (CART-IR) and non-CART-immunoreactive MCH-ergic neuron subpopulations was found only after selective REM deprivation, it was absent in the large platform (stress control) rebound group

  4. Communication architectures for systems-on-chip

    CERN Document Server

    Ayala, Jose L

    2011-01-01

    A presentation of state-of-the-art approaches from an industrial applications perspective, Communication Architectures for Systems-on-Chip shows professionals, researchers, and students how to attack the problem of data communication in the manufacture of SoC architectures. With its lucid illustration of current trends and research improving the performance, quality, and reliability of transactions, this is an essential reference for anyone dealing with communication mechanisms for embedded systems, systems-on-chip, and multiprocessor architectures--or trying to overcome existing limitations.

  5. Additive manufacturing – a sustainable manufacturing route

    Directory of Open Access Journals (Sweden)

    Frăţilă Domniţa

    2017-01-01

    Full Text Available Additive Manufacturing (AM technologies allow developing and manufacturing very complex shaped parts and functional products with a high level of customization, being a great alternative to Traditional Manufacturing (TM methods like injection molding, die-casting or machining. Due to the importance of cleaner production in the field of manufacturing processes, sustainability of AM processes needs to be assessed in order to make easier its acceptance and implementation in the industry. Furthermore, the manufacturers can improve their competitiveness and profitability by considering the ecological aspects during the manufacturing step of a product. This paper gives a survey on sustainability issues related to AM.

  6. STUDY ON USING WASTE ORGANIC SILK TO MANUFACTURE ACTIVATED CARBON FIBER%废旧有机丝制备活性炭纤维的研究

    Institute of Scientific and Technical Information of China (English)

    杨建利; 杜美利; 黄婕; 王健

    2012-01-01

    活性炭纤维是以高聚物为原料,经高温炭化和活化而制成的一种纤维状高效吸附分离材料.利用废旧有机丝为原料,探索在不同工艺条件下制取活性炭纤维的可行性.经扫描电镜、X射线衍射、红外分光光度计及亚甲基蓝吸附实验分析得出优化的工艺条件为:炭化温度,650℃;用CO2活化,活化温度为950℃,活化时间为60 min,制得吸附性能优良的活性炭纤维.%The activated carbon fiber is a kind of highly effective separation and adsorption material, which takes polymer as raw material while carbonization and activation in high temperature. In this study, we use waste organic silk as raw material, seek feasibility to manufacture activated carbon fiber in different condition. In the end, through the SEM, XRD, IR and adsorption of methylene blue trihydrate, we has preparated excellent performance activated carbon fiber and concluded optimal conditions: carbonization temperature is 650 ℃ , activation is in CO2 atmosphere, activation temperature is 950 ℃, activation time is 60 min.

  7. Resources publication and discovery in manufacturing grid

    Institute of Scientific and Technical Information of China (English)

    TAO Fei; HU Ye-fa; DING Yu-feng; SHENG Bu-yun; ZHOU Zu-de

    2006-01-01

    In the manufacturing grid's architecture, Resources Management System (RMS) is the central component responsible for disseminating resource information across the grid, accepting requests for resources, discovering and scheduling the suitable resources that match the requests for the global grid resource, and executing the requests on scheduled resources. In order to resolve the problem of resources publication and discovery in Manufacturing Grid (MGrid), the classification of manufacturing resources is first researched after which the resources encapsulation class modes are put forward. Then, a scalable two-level resource management architecture is constructed on the model, which includes root nodes, domain nodes and leaf nodes. And then an RMS is proposed, and the resources publication and discovery mechanism are detailedly described. At last, an application prototype is developed to show the validity and the practicability of the proved theory and method.

  8. From green architecture to architectural green

    DEFF Research Database (Denmark)

    Earon, Ofri

    2011-01-01

    they have overshadowed the architectural potential of green architecture. The paper questions how a green space should perform, look like and function. Two examples are chosen to demonstrate thorough integrations between green and space. The examples are public buildings categorized as pavilions. One....... Architectural green could signify green architecture with inclusive interrelations between green and space, built and unbuilt, inside and outside. The aim of the term is to reflect a new focus in green architecture – its architectural performance. Ecological issues are not underestimated or ignored, but so far......The paper investigates the topic of green architecture from an architectural point of view and not an energy point of view. The purpose of the paper is to establish a debate about the architectural language and spatial characteristics of green architecture. In this light, green becomes an adjective...

  9. Textile Architecture

    DEFF Research Database (Denmark)

    Heimdal, Elisabeth Jacobsen

    2010-01-01

    Textiles can be used as building skins, adding new aesthetic and functional qualities to architecture. Just like we as humans can put on a coat, buildings can also get dressed. Depending on our mood, or on the weather, we can change coat, and so can the building. But the idea of using textiles...... to create human habitation is not new. As Diether S. Hope phrases it, referring to tents: The history of development of humanity would be barely conceivable without free spanning textile membrane structures....

  10. Catalyst Architecture

    DEFF Research Database (Denmark)

    Kiib, Hans; Marling, Gitte; Hansen, Peter Mandal

    2014-01-01

    of programs, have a role in mediating positive social and/or cultural development. In this sense, we talk about architecture as a catalyst for: sustainable adaptation of the city’s infrastructure appropriate renovation of dilapidated urban districts strengthening of social cohesiveness in the city development...... meaningful for everyone. The exhibited works are designed by SANAA, Diller Scofidio + Renfro, James Corner Field Operation, JBMC Arquitetura e Urbanismo, Atelier Bow-Wow, Ateliers Jean Nouvel, COBE, Transform, BIG, Topotek1, Superflex, and by visual artist Jane Maria Petersen....

  11. Architectural dreaming

    Institute of Scientific and Technical Information of China (English)

    Mark Godfrey

    2004-01-01

    <正> For the first 800 years of its existence, Beijing retained essentially the same character: a walled palace city at its centre, organised on a strict north-south axis and contained within a sea of courtyard houses along lanes too narrow forcars. Today Beijing’s basic unit of architectural scale has become the skyscraper, erected a dozen at a time and facing massive highways. Ancient buildings are so small and unloved by comparison that they threaten to disappear from view. Fuelled by an economic boom, and propelled by banks flushed with mortgage cash, Beijing has embarked on the largest building campaign the world has ever seen.

  12. Synthesis of Bi{sub 2}O{sub 3} architectures in DMF–H{sub 2}O solution by precipitation method and their photocatalytic activity

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Li-Li; Han, Qiao-Feng, E-mail: hanqiaofeng@njust.edu.cn; Zhao, Jin; Zhu, Jun-Wu; Wang, Xin, E-mail: wangx@njust.edu.cn; Ma, Wei-Hua

    2014-11-25

    Graphical abstract: Flowerlike α-Bi{sub 2}O{sub 3} architectures assembled by nanobrick-based petals with pineapple surface were firstly synthesized by precipitation method at room temperature in DMF–H{sub 2}O solution. - Highlights: • Nanobrick-based flowerlike Bi{sub 2}O{sub 3} crystals with pineapple surface were synthesized by precipitation method. • Good solubility of Bi(NO{sub 3}){sub 3} in DMF played a crucial role in the growth of flowerlike Bi{sub 2}O{sub 3}. • The growth mechanism of Bi{sub 2}O{sub 3} microcrystallites has been explained in detail. - Abstract: Well-crystalline flowerlike α-Bi{sub 2}O{sub 3} hierarchical architectures with pineapple-shaped petals have been synthesized by precipitation method at a volume ratio of DMF/H{sub 2}O of 5, where DMF and H{sub 2}O were used to dissolve Bi(NO{sub 3}){sub 3} and KOH, respectively. If the DMF/H{sub 2}O ratio was decreased to 2:1, 1:1 and 0:30, flower-, bundle- and dendrite-shaped α-Bi{sub 2}O{sub 3} microcrystallites aggregated by nanorods were formed, respectively. The simple synthetic route and thus obtained Bi{sub 2}O{sub 3} architectures of various morphologies provide a basis insight for their formation mechanism. The photocatalytic activity of the as-prepared Bi{sub 2}O{sub 3} particles for degradation of Rhodamine B (RhB) under visible-light irradiation was obviously influenced by their morphologies. Bi{sub 2}O{sub 3} of nanorod-based microstructures exhibited higher photodegradation activity than nanobrick-based ones, owing to higher light absorption and carrier separation efficiency in one-dimensional (1D) nanostructured materials.

  13. Additive manufacturing – a sustainable manufacturing route

    OpenAIRE

    Frăţilă Domniţa; Rotaru Horaţiu

    2017-01-01

    Additive Manufacturing (AM) technologies allow developing and manufacturing very complex shaped parts and functional products with a high level of customization, being a great alternative to Traditional Manufacturing (TM) methods like injection molding, die-casting or machining. Due to the importance of cleaner production in the field of manufacturing processes, sustainability of AM processes needs to be assessed in order to make easier its acceptance and implementation in the industry. Furth...

  14. Biofunctional composite coating architectures based on polycaprolactone and nanohydroxyapatite for controlled corrosion activity and enhanced biocompatibility of magnesium AZ31 alloy

    Energy Technology Data Exchange (ETDEWEB)

    Zomorodian, A., E-mail: amir.zomorodian@ist.utl.pt [ICEMS-DEQ, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa (Portugal); Garcia, M.P. [Laboratory for Bone Metabolism and Regeneration, Faculty of Dental Medicine, University of Porto, Porto (Portugal); Moura e Silva, T. [ICEMS-DEQ, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa (Portugal); ISEL, Department of Mechanical Engineering, 1959-007 Lisboa (Portugal); Fernandes, J.C.S. [ICEMS-DEQ, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa (Portugal); Fernandes, M.H. [Laboratory for Bone Metabolism and Regeneration, Faculty of Dental Medicine, University of Porto, Porto (Portugal); Montemor, M.F. [ICEMS-DEQ, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa (Portugal)

    2015-03-01

    In this work a biofunctional composite coating architecture for controlled corrosion activity and enhanced cellular adhesion of AZ31 Mg alloys is proposed. The composite coating consists of a polycaprolactone (PCL) matrix modified with nanohydroxyapatite (HA) applied over a nanometric layer of polyetherimide (PEI). The protective properties of the coating were studied by electrochemical impedance spectroscopy (EIS), a non-disturbing technique, and the coating morphology was investigated by field emission scanning electron microscopy (FE-SEM). The results show that the composite coating protects the AZ31 substrate. The barrier properties of the coating can be optimized by changing the PCL concentration. The presence of nanohydroxyapatite particles influences the coating morphology and decreases the corrosion resistance. The biocompatibility was assessed by studying the response of osteoblastic cells on coated samples through resazurin assay, confocal laser scanning microscopy (CLSM) and scanning electron microscopy (SEM). The results show that the polycaprolactone to hydroxyapatite ratio affects the cell behavior and that the presence of hydroxyapatite induces high osteoblastic differentiation. - Highlights: • A biofunctional coating architecture for bioresorbable AZ31 Mg alloys is proposed. • The composite coating provides corrosion protection of the bare material. • The coating enhances alkaline phosphatase activity of osteoblastic cells. • The presence of hydroxyapatite results in higher osteoblastic differentiation.

  15. Desktop Manufacturing Technologies.

    Science.gov (United States)

    Snyder, Mark

    1991-01-01

    Desktop manufacturing is the use of data from a computer-assisted design system to construct actual models of an object. Emerging processes are stereolithography, laser sintering, ballistic particle manufacturing, laminated object manufacturing, and photochemical machining. (SK)

  16. Self-assembly, redox activity, and charge transport of functional surface nano-architectures by molecular design

    Science.gov (United States)

    Skomski, Daniel

    Surface-assisted molecular self-assembly is a promising strategy to program the structure and chemical state of atoms and molecules in nano-architectures to achieve a specific function. The experiments described in this thesis demonstrate that the design and programming of basic organic components leads to desired characteristics by self-assembly. The fabrication of uniform single-site metal centers at surfaces, important for high selectivity in next-generation catalysts, was accomplished by coordination to redox non-innocent phenanthroline and tetrazine-based ligands. These examples were the first demonstrating tuning of the metal oxidation state in surface coordination architectures through rational ligand design. The molecular-scale coordination architectures were the first formed from chromium and vanadium, and the first from platinum in a non-porphyrin system. The first mixed valence metal-ligand surface structure was fabricated that attained the same ligand coordination number for all metal sites. A new surface reaction method was demonstrated between an inexpensive sodium chloride reagent and carboxylate ligands. High-temperature, molecular-resolution microscopy and spectroscopy of the ordered metal-organic structures demonstrated thermal stability up to 300 °C, the highest molecular-level thermal stability in organic surface nanostructures yet achieved, making such systems potential candidates for moderate-temperature catalytic reactions. Molecular self-assembly was expanded into organic semiconductor thin films. In a two-component, bi-layered system, hydrogen bonding between carboxylates and carboxylic acid-substituted thiophenes was utilized, yielding the first real-space images of phenyl-thiophene stacking. In a one-component system, multiple donor-acceptor pi-pi contacts between phenyltriazole building blocks accomplished assembly of flat-lying molecules from a surface with molecular-scale precision through more than twenty molecular layers. Sufficient

  17. Developing A System Architecture For Holonic Shop Floor Control

    DEFF Research Database (Denmark)

    Sørensen, Christian; Langer, Gilad; Alting, Leo

    1998-01-01

    This paper describes theresults of research regarding the emerging theory of Holonic Manufacturing Systems. This theory and in particular itscorresponding reference architecture serves as the basis for thedevelopment of a system-architecture for shop floor controlsystems in a multi-cellular conte...

  18. Tribology in Manufacturing Technology

    CERN Document Server

    2013-01-01

    The present book aims to provide research advances on tribology in manufacturing technology for modern industry. This book can be used as a research book for final undergraduate engineering course (for example, mechanical, manufacturing, materials, etc) or as a subject on manufacturing at the postgraduate level. Also, this book can serve as a useful reference for academics, manufacturing and tribology researchers, mechanical, mechanical, manufacturing and materials engineers, professionals in related industries with manufacturing and tribology.

  19. Effect of lead (Pb) exposure on the activity of superoxide dismutase and catalase in battery manufacturing workers (BMW) of Western Maharashtra (India) with reference to heme biosynthesis.

    Science.gov (United States)

    Patil, Arun J; Bhagwat, Vinod R; Patil, Jyotsna A; Dongre, Nilima N; Ambekar, Jeevan G; Jailkhani, Rama; Das, Kusal K

    2006-12-01

    The aim of this study was to estimate the activity of superoxide dismutase (SOD) and catalase in erythrocytes and malondialdehyde (MDA) in plasma of battery manufacturing workers (BMW) of Western Maharashtra (India) who were occupationally exposed to lead (Pb) over a long period of time (about 15 years). This study was also aimed to determine the Pb intoxication resulted in a disturbance of heme biosynthesis in BMW group. The blood Pb level of BMW group (n = 28) was found to be in the range of 25.8 - 78.0 microg/dL (mean + SD, 53.63 + 16.98) whereas in Pb unexposed control group (n = 35) the range was 2.8 - 22.0 microg/dL (mean + SD, 12.52 + 4.08). The blood level (Pb-B) and urinary lead level (Pb-U) were significantly increased in BMW group as compared to unexposed control. Though activated d- aminolevulinic acid dehydratase (ALAD) activities in BMW group did not show any significant change when compared to control group but activated / non activated erythrocyte - ALAD activities in BMW group showed a significant increase. Erythrocyte- zinc protoporphyrin (ZPP), urinary daminolevulinic acid (ALA-U) and porphobilinogen (PBG-U) of BMW groups elevated significantly as compared to control. A positive correlation (r = 0.66, p BMW group but no such significant correlation (r = 0.02, p> 1.0) were observed in control group. Hematological study revealed a significant decrease of hemoglobin concentration, packed cell volume (%) and other blood indices and a significant increase of total leucocytes count in BMW group in comparison to control group. The serum MDA content was significantly increased (p BMW group as compared to control group. A positive correlation (r = 0.45, p BMW group (Pb-B range 25.8 - 78.0 microg / dL) but such significant correlation did not notice in control group (Pb-B range 2.8 - 22.0 microg / dL). The study clearly showed an adverse effect of heme biosynthesis and imbalance of pro-oxidant / antioxidant status in lead exposed battery manufacturing

  20. Lab architecture

    Science.gov (United States)

    Crease, Robert P.

    2008-04-01

    There are few more dramatic illustrations of the vicissitudes of laboratory architecturethan the contrast between Building 20 at the Massachusetts Institute of Technology (MIT) and its replacement, the Ray and Maria Stata Center. Building 20 was built hurriedly in 1943 as temporary housing for MIT's famous Rad Lab, the site of wartime radar research, and it remained a productive laboratory space for over half a century. A decade ago it was demolished to make way for the Stata Center, an architecturally striking building designed by Frank Gehry to house MIT's computer science and artificial intelligence labs (above). But in 2004 - just two years after the Stata Center officially opened - the building was criticized for being unsuitable for research and became the subject of still ongoing lawsuits alleging design and construction failures.

  1. Generalized Reactive Manufacturing System

    Institute of Scientific and Technical Information of China (English)

    李蓓智

    2001-01-01

    Generalized reactive manufacturing system named GRMS is introduced. GRMS is a human-centered system based on Multi-agent. Its management and control organization is made up of three types of agents named device agent,task agent and shop-floor agent. GRMS adopts a top down and bottom- up competition and cooperation strategy based on the dynamic sifter and funnel To constrain the behavior of agents, a reward and penaity policy is introduced into the system and the closed-loop adjustment of GRMS is realized through such policy.Agents for the same task should be cooperated with each other and agents for different tasks should compete for survival in the dynamic changing environment. A distributed-hierarchical architecture with three levels of master-slave relationships among agents are proposed.Self-propelled process planning is also discussed. In order to evaluate GRMS, a time-driven simulation system-GRMOSS is developed to check the physical consistency of GRMS.

  2. Basic design in architectural education in Turkey

    Directory of Open Access Journals (Sweden)

    Makaklı Elif Süyük

    2016-01-01

    Full Text Available Creative activity is one of the most significant parts of architectural education. In the architectural curriculum organisation ‘design studio’ is the unique and preeminent subject. Freshman students encounter ‘design’ first in basic design course, before they know what designing incorporates. The Basic Design is the starting point of initiating creativity in architecture education. It helps each student to understand architecture as a creative and innovative practice in the first year of education. This study analyzes the characteristics of basic design course, the topics of the course contents and its significance in the architectural curriculum in Turkey as well.

  3. “喜庆文化”融合“绿色建筑”理念的厂区环境景观设计——以中烟公司广州生产基地为例%Combined Happy Culture with Green Architecture in EnviromentLandscape Design -Take the China Tobacco CoorperationManufacture Base in Guangzhou as Example

    Institute of Scientific and Technical Information of China (English)

    彭莉霞; 陈志

    2011-01-01

    This paper expatiates the architecture environment landscape design of the china tobacco Coor-peration Manufacture Base in Guangzhou. Combining the specialbility of the "double happy breed" of the products in this coorperation, on the basis of introducing green architecture logos, promoting and developing the happy culture in the landscape, the overall layouts, the environment landscape and some garden essays have been designed in this item, some special landscapes such as the gaet, the union factor,the technological laboratory and the happy square have been plotted in this paper, four district have been plotted around the centre of the factor,they are ;the east fragrang and jade green; the south clear ring satisfaction; the west warm grass fruit mountain; the north red bamboo hear happy.%文章阐述了中烟公司广州生产基地易地技改项目环境景观工程的设计方案,方案结合该公司产品“双喜”品牌的特点,通过在园林中大力弘扬“喜庆文化”,引入“绿色建筑”的理念,对生产基地进行总体规划以及对环境景观与园林小品进行详细设计.文中重点介绍了基地大门、联合工房、技术实验室与如意广场等特色景观以及厂房周围的4个区域:东区的东芳叠翠,南区的澄环如意,西区的草暖果岭,北区的丹竹闻喜的设计特点.

  4. Behavior models for software architecture

    OpenAIRE

    Auguston, Mikhail

    2014-01-01

    Approved for public release; distribution is unlimited. Approved for public release; distribution is unlimited Monterey Phoenix (MP) is an approach to formal software system architecture specification based on behavior models. Architecture modeling focuses not only on the activities and interactions within the system, but also on the interactions between the system and its environment, providing an abstraction for interaction specification. The behavior of the system is defined as a set...

  5. Decoding the architectural theory

    Institute of Scientific and Technical Information of China (English)

    Gu Mengchao

    2008-01-01

    Starting from the illustration of the definition and concept of the architectural theory, the author established his unique understanding about the framework of the architectural theory and the innovation of the architectural theory underlined by Chinese characteristics.

  6. Readout Architecture for Hybrid Pixel Readout Chips

    CERN Document Server

    AUTHOR|(SzGeCERN)694170; Westerlund, Tomi; Wyllie, Ken

    The original contribution of this thesis to knowledge are novel digital readout architectures for hybrid pixel readout chips. The thesis presents asynchronous bus-based architecture, a data-node based column architecture and a network-based pixel matrix architecture for data transportation. It is shown that the data-node architecture achieves readout efficiency 99 % with half the output rate as a bus-based system. The network-based solution avoids ``broken'' columns due to some manufacturing errors, and it distributes internal data traffic more evenly across the pixel matrix than column-based architectures. An improvement of $>$ 10 % to the efficiency is achieved with uniform and non-uniform hit occupancies. Architectural design has been done using transaction level modeling ($TLM$) and sequential high-level design techniques for reducing the design and simulation time. It has been possible to simulate tens of column and full chip architectures using the high-level techniques. A decrease of $>$ 10 in run-time...

  7. SUSTAINABLE ARCHITECTURE : WHAT ARCHITECTURE STUDENTS THINK

    OpenAIRE

    SATWIKO, PRASASTO

    2013-01-01

    Sustainable architecture has become a hot issue lately as the impacts of climate change become more intense. Architecture educations have responded by integrating knowledge of sustainable design in their curriculum. However, in the real life, new buildings keep coming with designs that completely ignore sustainable principles. This paper discusses the results of two national competitions on sustainable architecture targeted for architecture students (conducted in 2012 and 2013). The results a...

  8. Performative Urban Architecture

    DEFF Research Database (Denmark)

    Thomsen, Bo Stjerne; Jensen, Ole B.

    The paper explores how performative urban architecture can enhance community-making and public domain using socio-technical systems and digital technologies to constitute an urban reality. Digital medias developed for the web are now increasingly occupying the urban realm as a tool for navigating...... the perspectives of using interactive technologies for performative objects, which are able to register the impulses of urban activity and reproduce the contexts of the city. In this way the performative environment is established as an event setting providing an embodied experience as a ‘quasi-object' that can...... couple relationships between architecture, humans and society. These performative relationships between digital and physical environments are seen as illustrative of the social production of space by performance and the creative production of identity. The paper reflects on the perspectives...

  9. Modeling Architectural Patterns Using Architectural Primitives

    NARCIS (Netherlands)

    Zdun, Uwe; Avgeriou, Paris

    2005-01-01

    Architectural patterns are a key point in architectural documentation. Regrettably, there is poor support for modeling architectural patterns, because the pattern elements are not directly matched by elements in modeling languages, and, at the same time, patterns support an inherent variability that

  10. Lightweight enterprise architectures

    CERN Document Server

    Theuerkorn, Fenix

    2004-01-01

    STATE OF ARCHITECTUREArchitectural ChaosRelation of Technology and Architecture The Many Faces of Architecture The Scope of Enterprise Architecture The Need for Enterprise ArchitectureThe History of Architecture The Current Environment Standardization Barriers The Need for Lightweight Architecture in the EnterpriseThe Cost of TechnologyThe Benefits of Enterprise Architecture The Domains of Architecture The Gap between Business and ITWhere Does LEA Fit? LEA's FrameworkFrameworks, Methodologies, and Approaches The Framework of LEATypes of Methodologies Types of ApproachesActual System Environmen

  11. Software architecture 2

    CERN Document Server

    Oussalah, Mourad Chabanne

    2014-01-01

    Over the past 20 years, software architectures have significantly contributed to the development of complex and distributed systems. Nowadays, it is recognized that one of the critical problems in the design and development of any complex software system is its architecture, i.e. the organization of its architectural elements. Software Architecture presents the software architecture paradigms based on objects, components, services and models, as well as the various architectural techniques and methods, the analysis of architectural qualities, models of representation of architectural templa

  12. Software architecture 1

    CERN Document Server

    Oussalah , Mourad Chabane

    2014-01-01

    Over the past 20 years, software architectures have significantly contributed to the development of complex and distributed systems. Nowadays, it is recognized that one of the critical problems in the design and development of any complex software system is its architecture, i.e. the organization of its architectural elements. Software Architecture presents the software architecture paradigms based on objects, components, services and models, as well as the various architectural techniques and methods, the analysis of architectural qualities, models of representation of architectural template

  13. HRST architecture modeling and assessments

    Science.gov (United States)

    Comstock, Douglas A.

    1997-01-01

    This paper presents work supporting the assessment of advanced concept options for the Highly Reusable Space Transportation (HRST) study. It describes the development of computer models as the basis for creating an integrated capability to evaluate the economic feasibility and sustainability of a variety of system architectures. It summarizes modeling capabilities for use on the HRST study to perform sensitivity analysis of alternative architectures (consisting of different combinations of highly reusable vehicles, launch assist systems, and alternative operations and support concepts) in terms of cost, schedule, performance, and demand. In addition, the identification and preliminary assessment of alternative market segments for HRST applications, such as space manufacturing, space tourism, etc., is described. Finally, the development of an initial prototype model that can begin to be used for modeling alternative HRST concepts at the system level is presented.

  14. Chip architecture - A revolution brewing

    Science.gov (United States)

    Guterl, F.

    1983-07-01

    Techniques being explored by microchip designers and manufacturers to both speed up memory access and instruction execution while protecting memory are discussed. Attention is given to hardwiring control logic, pipelining for parallel processing, devising orthogonal instruction sets for interchangeable instruction fields, and the development of hardware for implementation of virtual memory and multiuser systems to provide memory management and protection. The inclusion of microcode in mainframes eliminated logic circuits that control timing and gating of the CPU. However, improvements in memory architecture have reduced access time to below that needed for instruction execution. Hardwiring the functions as a virtual memory enhances memory protection. Parallelism involves a redundant architecture, which allows identical operations to be performed simultaneously, and can be directed with microcode to avoid abortion of intermediate instructions once on set of instructions has been completed.

  15. How architecture students gain and apply knowledge of sustainable architecture

    DEFF Research Database (Denmark)

    Donovan, Elizabeth; Holder, Anna

    2016-01-01

    This paper will reflect on understandings of architectural pedagogy and the integration of sustainability into architectural design education. This is framed within an understanding of the construction industry’s role in the production of waste. Despite the complexity of global environmental crises...... teaching is partially integrated within the design studio courses. We compare the institution’s philosophy for sustainability with pedagogical approaches as practiced within the school. An empirical study was made of 2nd year architecture student experiences of a one-month introduction course to ‘Reuse...... and materials’. Within this, the students’ baseline knowledge of sustainable architecture was compared with their subsequent understandings and the opinions they formed. Our findings emphasise the importance of students’ personal critical reflection and active engagement but also the need for students...

  16. Inhibitory activity of Lactobacillus plantarum LMG P-26358 against Listeria innocua when used as an adjunct starter in the manufacture of cheese

    LENUS (Irish Health Repository)

    2011-08-30

    Abstract Lactobacillus plantarum LMG P-26358 isolated from a soft French artisanal cheese produces a potent class IIa bacteriocin with 100% homology to plantaricin 423 and bacteriocidal activity against Listeria innocua and Listeria monocytogenes. The bacteriocin was found to be highly stable at temperatures as high as 100°C and pH ranges from 1-10. While this relatively narrow spectrum bacteriocin also exhibited antimicrobial activity against species of enterococci, it did not inhibit dairy starters including lactococci and lactobacilli when tested by well diffusion assay (WDA). In order to test the suitability of Lb. plantarum LMG P-26358 as an anti-listerial adjunct with nisin-producing lactococci, laboratory-scale cheeses were manufactured. Results indicated that combining Lb. plantarum LMG P-26358 (at 108 colony forming units (cfu)\\/ml) with a nisin producer is an effective strategy to eliminate the biological indicator strain, L. innocua. Moreover, industrial-scale cheeses also demonstrated that Lb. plantarum LMG P-26358 was much more effective than the nisin producer alone for protection against the indicator. MALDI-TOF mass spectrometry confirmed the presence of plantaricin 423 and nisin in the appropriate cheeses over an 18 week ripening period. A spray-dried fermentate of Lb. plantarum LMG P-26358 also demonstrated potent anti-listerial activity in vitro using L. innocua. Overall, the results suggest that Lb. plantarum LMG P-26358 is a suitable adjunct for use with nisin-producing cultures to improve the safety and quality of dairy products.

  17. Comparing Architectural Styles for Service-Oriented Architectures - a REST vs. SOAP Case Study

    Science.gov (United States)

    Becker, Jörg; Matzner, Martin; Müller, Oliver

    Two architectural styles are currently heavily discussed regarding the design of service-oriented architectures (SOA). Within this chapter we have compared those two alternative styles - the SOAP-style with procedural designs similar to remote procedure calls and the REST-style with loosely coupled services similar to resources of the World Wide Web. We introduce the case of a business network consisting of manufacturers and service providers of the electronics industry for deriving a set of requirements towards a specific SOA implementation. For each architectural style we present a concrete SOA design and evaluate it against the defined set of requirements.

  18. Manufacturing network evolution

    DEFF Research Database (Denmark)

    Yang, Cheng; Farooq, Sami; Johansen, John

    2011-01-01

    Purpose – This paper examines the effect of changes at the manufacturing plant level on other plants in the manufacturing network and also investigates the role of manufacturing plants on the evolution of a manufacturing network. Design/methodology/approach –The research questions are developed...... by identifying the gaps in the reviewed literature. The paper is based on three case studies undertaken in Danish manufacturing companies to explore in detail their manufacturing plants and networks. The cases provide a sound basis for developing the research questions and explaining the interaction between...... different manufacturing plants in the network and their impact on network transformation. Findings – The paper highlights the dominant role of manufacturing plants in the continuously changing shape of a manufacturing network. The paper demonstrates that a product or process change at one manufacturing...

  19. Distributed optically integrated manufacture system based on CORBA

    Science.gov (United States)

    Cen, Ming; Jiang, Jian-chun; Liu, Xing-fa; Hu, Rui-fei

    2007-12-01

    Focused on the shortcoming and insufficiency of reconfigurable manufacture system (RMS) for optical manufacturing in control layer and interface of manufacturing execution systems (MES) and control layer, the difference of MES-plan layer interface and that of MES-control layer is discussed, and an architecture of distributed optically integrated manufacture executing system based on fieldbus/Ethernet network and common object request broker architecture (CORBA) is presented. In this solution, the optical manufacture equipments are connected by fieldbus network, a gateway is used for the communication of fieldbus manufacture equipment and MES in the workshop, and CORBA services which provide a general interface for communication of heterogeneous fieldbus manufacture equipment of workshop are realized on the gateway. Then all specifics of heterogeneous fieldbus manufacture equipments are concealed, which show as virtual equipment and can be accessed in a simple and unified way. So the control layer is composed of virtual equipment and easy to be reconfigured. Similarly workshop management function components are modeled and encapsulated by CORBA interface, and MES could be integrated to RMS expediently. The optical integrated manufacture system presented is proved with good ability of flexible, reconfigurable, opening and high feasibility, and met the reconfigurable requirement of distributed optical manufacturing workshop preferably.

  20. Role of Ontologies for CPS Implementation in Manufacturing

    Directory of Open Access Journals (Sweden)

    Garetti Marco

    2015-12-01

    Full Text Available Cyber Physical Systems are an evolution of embedded systems featuring a tight combination of collaborating computational elements that control physical entities. CPSs promise a great potential of innovation in many areas including manufacturing and production. This is because we obtain a very powerful, flexible, modular infrastructure allowing easy (re configurability and fast ramp-up of manufacturing applications by building a manufacturing system with modular mechatronic components (for machining, transportation and storage and embedded intelligence, by integrating them into a system, through a network connection. However, when building such kind of architectures, the way to supply the needed domain knowledge to real manufacturing applications arises as a problem to solve. In fact, a CPS based architecture for manufacturing is made of smart but independent manufacturing components without any knowledge of the role they have to play together in the real world of manufacturing applications. Ontologies can supply such kind of knowledge, playing a very important role in CPS for manufacturing. The paper deals with this intriguing theme, also presenting an implementation of this approach in a research project for the open automation of manufacturing systems, in which the power of CPS is complemented by the support of an ontology of the manufacturing domain.

  1. The Networked Manufacturing Resources Optimizing Configuration System and Its Partners Selection Method

    Institute of Scientific and Technical Information of China (English)

    DONG Zhao-yang; SUN Shu-dong

    2006-01-01

    The three levels optimizing strategy is put forward for the networked manufacturing resources optimizing configuration, namely, the optimizing of a logical manufacturing process,the optimizing of simulation-based integration of process planning and scheduling, and the optimizing of networked production scheduling. Then, the web services-based architecture of networked manufacturing resources optimizing configuration is brought forward. Finally, the key algorithm of the networked manufacturing resources optimizing configuration is discussed, namely, the two phases manufacturing partners selection method, which including the group technology-based manufacturing resources pre-configuration and the genetic algorithm-based executable manufacturing process optimizing.

  2. Effects of tea infusions of various varieties or different manufacturing types on inhibition of mouse mast cell activation.

    Science.gov (United States)

    Maeda-Yamamoto, M; Kawahara, H; Matsuda, N; Nesumi, K; Sano, M; Tsuji, K; Kawakami, Y; Kawakami, T

    1998-11-01

    We investigated effects of various tea infusions on mast cell activation using mouse mast cells. Among various tea extracts, infusions from cultivar 'Benihomare' and Taiwan lineage strongly inhibited histamine release after Fc epsilon RI cross-linking. Among three types of tea (from cultivar 'Benihomare'), extract from oolong tea or black tea inhibited histamine release more strongly than green tea extract. Furthermore, 'Benihomare' oolong tea extract suppressed tyrosine phosphorylation of cellular proteins after Fc epsilon RI cross-linking, but polyvinyl polypyrrolidone treatment of the extract to remove phenolic compounds, weakened the suppressive effect.

  3. Materials Driven Architectural Design and Representation

    DEFF Research Database (Denmark)

    Kruse Aagaard, Anders

    2015-01-01

    another role in relation to architectural production. It is, in this paper, the intention to point at material research as an active initiator in explorative approaches to architectural design methods and architectural representation. This paper will point at the inclusion of tangible and experimental......This paper aims to outline a framework for a deeper connection between experimentally obtained material knowledge and architectural design. While materials and architecture in the process of realisation are tightly connected, architectural design and representation are often distanced from...... the material domain in which the construction eventually will happen. In many cases, it can seem that materials play the role of a selection of building blocks from which a determined architectural vision or representation are tried to be build. Research in materials, materials behaviour and new materials...

  4. Enabling globalization of manufacturing through supply chain improvement programs

    DEFF Research Database (Denmark)

    Farooq, Sami; Dukovska-Popovska, Iskra; Boer, Harry

    2012-01-01

    This paper investigates the association between globalization of manufacturing activities and seven upstream and downstream oriented supply chain action programs. The paper also examines the relationship between nine globalization objectives and global manufacturing activities. The study is based...

  5. Research on Cloud Manufacturing Resource-Aware and Access Technology Using RFID

    Institute of Scientific and Technical Information of China (English)

    Min Lv; ChuanXia Zhou; JiShuai Shi; Lei Liu

    2014-01-01

    With the continuous development of cloud manufacturing technology, in order to solve more complex manufacturing problem and conduct large-scale networked manufacturing, combining with the characteristic of discrete manufacturing enterprise ’ s demands and RFID ( Radio Frequency Identification ) , a kind of RFID-based cloud manufacturing resource-aware and access technology is proposed. Firstly, the architecture of the cloud manufacturing system and RFID system is briefly introduced. Then, the key technologies of manufacturing resource-aware and access technology are analyzed, including anti-collision technology, reader management technology and so on. Finally, taking the manufacturing of the key components in discrete manufacturing enterprise as an example, the practicality and feasibility of the technology is verified. The results show that the application of this technology provides a strong guarantee for the sharing and collaboration of manufacturing resources and capacity in the discrete manufacturing industry.

  6. Effect of Lead (Pb Exposure on the Activity of Superoxide Dismutase and Catalase in Battery Manufacturing Workers (BMW of Western Maharashtra (India with Reference to Heme biosynthesis

    Directory of Open Access Journals (Sweden)

    Kusal K. Das

    2006-12-01

    Full Text Available The aim of this study was to estimate the activity of superoxide dismutase (SOD and catalase in erythrocytes and malondialdehyde (MDA in plasma of battery manufacturing workers (BMW of Western Maharashtra (India who were occupationally exposed to lead (Pb over a long period of time (about 15 years. This study was also aimed to determine the Pb intoxication resulted in a disturbance of heme biosynthesis in BMW group. The blood Pb level of BMW group (n = 28 was found to be in the range of 25.8 – 78.0 μg/dL (mean + SD, 53.63 + 16.98 whereas in Pb unexposed control group (n = 35 the range was 2.8 – 22.0 μg/dL (mean + SD, 12.52 + 4.08. The blood level (Pb-B and urinary lead level (Pb-U were significantly increased in BMW group as compared to unexposed control. Though activated d- aminolevulinic acid dehydratase (ALAD activities in BMW group did not show any significant change when compared to control group but activated / non activated erythrocyte – ALAD activities in BMW group showed a significant increase. Erythrocyte- zinc protoporphyrin (ZPP, urinary daminolevulinic acid (ALA-U and porphobilinogen (PBG-U of BMW groups elevated significantly as compared to control. A positive correlation (r = 0.66, p 1.0 were observed in control group. Hematological study revealed a significant decrease of hemoglobin concentration, packed cell volume (% and other blood indices and a significant increase of total leucocytes count in BMW group in comparison to control group. The serum MDA content was significantly increased (p< 0.001 and the activities of antioxidant enzymes such as erythrocyte- SOD (p< 0.001 and erythrocytecatalase (p< 0.001 were significantly reduced in BMW group as compared to control group. A positive correlation (r = 0.45, p<0.02 between Pb-B and serum MDA level was observed in BMW group (Pb-B range 25.8 – 78.0 μg / dL but such significant correlation did not notice in

  7. Framework for Grid Manufacturing

    Institute of Scientific and Technical Information of China (English)

    陈笠; 邓宏; 邓倩妮; 吴振宇

    2004-01-01

    With the development of networked manufacturing, it is more and more imminent to solve problems caused by inherent limitations of network technology, such as heterogeneity, collaboration collision, and decentralized control.This paper presents a framework for grid manufacturing, which neatly combines grid technology with the infrastructure of advanced manufacturing technology.The paper studies grid-oriented knowledge description and acquisition, and constructs a distributed knowledge grid model.The paper also deals with the protocol of node description in collaborative design, and describes a distributed collaborative design model.The protocol and node technology leads to a collaborative production model for grid manufacturing.The framework for grid manufacturing offers an effective and feasible solution for the problems of networked manufacturing.The grid manufacturing will become an advanced distributed manufacturing model and promote the development of advanced manufacturing technologies.

  8. Architecture as Design Study.

    Science.gov (United States)

    Kauppinen, Heta

    1989-01-01

    Explores the use of analogies in architectural design, the importance of Gestalt theory and aesthetic cannons in understanding and being sensitive to architecture. Emphasizes the variation between public and professional appreciation of architecture. Notes that an understanding of architectural process enables students to improve the aesthetic…

  9. Can You Hear Architecture

    DEFF Research Database (Denmark)

    Ryhl, Camilla

    2016-01-01

    Taking an off set in the understanding of architectural quality being based on multisensory architecture, the paper aims to discuss the current acoustic discourse in inclusive design and its implications to the integration of inclusive design in architectural discourse and practice as well...... design and architectural quality for people with a hearing disability and a newly conducted qualitative evaluation research in Denmark as well as architectural theories on multisensory aspects of architectural experiences, the paper uses examples of existing Nordic building cases to discuss the role...... of acoustics in both inclusive design and multisensory architecture....

  10. Dynamic brain architectures in local brain activity and functional network efficiency associate with efficient reading in bilinguals.

    Science.gov (United States)

    Feng, Gangyi; Chen, Hsuan-Chih; Zhu, Zude; He, Yong; Wang, Suiping

    2015-10-01

    The human brain is organized as a dynamic network, in which both regional brain activity and inter-regional connectivity support high-level cognitive processes, such as reading. However, it is still largely unknown how the functional brain network organizes to enable fast and effortless reading processing in the native language (L1) but not in a non-proficient second language (L2), and whether the mechanisms underlying local activity are associated with connectivity dynamics in large-scale brain networks. In the present study, we combined activation-based and multivariate graph-theory analysis with functional magnetic resonance imaging data to address these questions. Chinese-English unbalanced bilinguals read narratives for comprehension in Chinese (L1) and in English (L2). Compared with L2, reading in L1 evoked greater brain activation and recruited a more globally efficient but less clustered network organization. Regions with both increased network efficiency and enhanced brain activation in L1 reading were mostly located in the fronto-temporal reading-related network (RN), whereas regions with decreased global network efficiency, increased clustering, and more deactivation in L2 reading were identified in the default mode network (DMN). Moreover, functional network efficiency was closely associated with local brain activation, and such associations were also modulated by reading efficiency in the two languages. Our results demonstrate that an economical and integrative brain network topology is associated with efficient reading, and further reveal a dynamic association between network efficiency and local activation for both RN and DMN. These findings underscore the importance of considering interregional connectivity when interpreting local BOLD signal changes in bilingual reading.

  11. Deindustrialization or metamorphosis of the industry. The new relationship between the manufacturing and tertiary activities; Desindustrializacion o metamorfosis de la instria?. La nueva relacion entre las actividades manufacturera y terciaria

    Energy Technology Data Exchange (ETDEWEB)

    Baro Tomas, E.

    2013-06-01

    The evolution of the manufacturing industry in recent decades has been subject to a complex process of transformation. Relevant changes have occurred in the composition of these activities, in the nature thereof and in the relationships established between the various productive sectors, especially the manufacturing sectors and an important part of the tertiary sectors. The analysis of these transformations requires a new viewpoint of what currently constitutes the industrial sector and, especially, a new definition of its effective perimeter. This new perimeter should incorporate a significant portion of tertiary activities: the services for production. In sum, we must put more emphasis on the complementary relationships that exist between the two types of activities, rather than considering the deindustrialization process as a simple shift of industrial activities by service activities. (Author) 33 refs.

  12. Distinct Polymer Architecture Mediates Switching of Complement Activation Pathways at the Nanosphere-Serum Interface: Implications for Stealth Nanoparticle Engineering

    DEFF Research Database (Denmark)

    Hamad, I.; Al-Hanbali, O.; Hunter, A.C.;

    2010-01-01

    Nanoparticles with surface projected polyethyleneoxide (PEO) chains in 'mushroom-brush' and "brush" configurations display stealth properties in systemic circulation and have numerous applications in site specific targeting for controlled drug delivery and release as well as diagnostic Imaging. W...... engineering and design of immunologically safer stealth and targetable nanosystems with polymers for use in clinical medicine.......Nanoparticles with surface projected polyethyleneoxide (PEO) chains in 'mushroom-brush' and "brush" configurations display stealth properties in systemic circulation and have numerous applications in site specific targeting for controlled drug delivery and release as well as diagnostic Imaging. We...... switches complement activation from C1q dependent classical to lectin pathway but also reduces the level of generated complement activation, products C4d, Bb, C5a, and SC5b-9. Also changes In adsorbed polymer configuration trigger alternative pathway activation differently and through different initiators...

  13. Functional webs for freeform architecture

    KAUST Repository

    Deng, Bailin

    2011-08-01

    Rationalization and construction-aware design dominate the issue of realizability of freeform architecture. The former means the decomposition of an intended shape into parts which are sufficiently simple and efficient to manufacture; the latter refers to a design procedure which already incorporates rationalization. Recent contributions to this topic have been concerned mostly with small-scale parts, for instance with planar faces of meshes. The present paper deals with another important aspect, namely long-range parts and supporting structures. It turns out that from the pure geometry viewpoint this means studying families of curves which cover surfaces in certain well-defined ways. Depending on the application one has in mind, different combinatorial arrangements of curves are required. We here restrict ourselves to so-called hexagonal webs which correspond to a triangular or tri-hex decomposition of a surface. The individual curve may have certain special properties, like being planar, being a geodesic, or being part of a circle. Each of these properties is motivated by manufacturability considerations and imposes constraints on the shape of the surface. We investigate the available degrees of freedom, show numerical methods of optimization, and demonstrate the effectivity of our approach and the variability of construction solutions derived from webs by means of actual architectural designs.

  14. Economic benefits of metrology in manufacturing

    DEFF Research Database (Denmark)

    Savio, Enrico; De Chiffre, Leonardo; Carmignato, S.

    2016-01-01

    In streamlined manufacturing systems, the added value of inspection activities is often questioned, and metrology in particular is sometimes considered only as an avoidable expense. Documented quantification of economic benefits of metrology is generally not available. This work presents concrete...... examples from industrial production, in which the added value of metrology in manufacturing is discussed and quantified. Case studies include: general manufacturing, forging, machining, and related metrology. The focus of the paper is on the improved effectiveness of metrology when used at product...

  15. An architecture for agile shop floor control systems

    DEFF Research Database (Denmark)

    Langer, Gilad; Alting, Leo

    2000-01-01

    manufacturing systems to accommodate the increasing dynamic characteristics of the manufacturing environment. Regarding these new concepts, specifically holonic manufacturing systems, there are many aspects that should be considered. One of the aspects is the manufacturing system and its control, commonly known...... as shop floor control. This paper presents the Holonic Multi-cell Control System (HoMuCS) architecture that allows for design and development of holonic shop floor control systems. The HoMuCS is a shop floor control system which is sometimes referred to as a manufacturing execution system......Changes in markets and global business trends affect the manufacturing environment in infinite ways. These changes have brought about the need for a paradigm shift to reassess the manner in which manufacturing systems are developed and operated. New theories and concepts present solutions to enable...

  16. Wire + Arc Additive Manufacturing

    OpenAIRE

    Williams, Stewart W.; Martina, Filomeno; Addison, Adrian C.; Ding, Jialuo; Pardal, Goncalo; Colegrove, Paul A.

    2016-01-01

    Depositing large components (>10 kg) in titanium, aluminium, steel and other metals is possible using Wire + Arc Additive Manufacturing. This technology adopts arc welding tools and wire as feedstock for additive manufacturing purposes. High deposition rates, low material and equipment costs, and good structural integrity make Wire+Arc Additive Manufacturing a suitable candidate for replacing the current method of manufacturing from solid billets or large forgings, especially with regards to ...

  17. Photosensitization of Carbon Nitride Photoelectrodes with CdS: A Novel Architecture with Highly Efficient Photocatalytic Activity

    Directory of Open Access Journals (Sweden)

    Xiaosong Zhou

    2014-01-01

    Full Text Available CdS with well-defined crystallinity is anchored on carbon nitride photoelectrodes by a successive chemical bath deposition. And the as-synthesized samples were characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, ultraviolet-visible diffuse reflection spectroscopy, X-ray photoelectron spectroscopy, and photoluminescence spectroscopy techniques. The effect of the amount of CdS on the catalytic activity for the degradation of acid Orange II is investigated under visible light irradiation. Results show that the photoelectrodes composed of CdS/CN exhibit much higher catalytic activity than pure CN photoelectrodes. A possible photocatalytic mechanism of the CdS/CN electrodes is proposed under visible light irradiation.

  18. Architecture and evolution of an Early Permian carbonate complex on a tectonically active island in east-central California

    Science.gov (United States)

    Stevens, Calvin H.; Magginetti, Robert T.; Stone, Paul

    2015-01-01

    The newly named Upland Valley Limestone represents a carbonate complex that developed on and adjacent to a tectonically active island in east-central California during a brief interval of Early Permian (late Artinskian) time. This lithologically unique, relatively thin limestone unit lies within a thick sequence of predominantly siliciclastic rocks and is characterized by its high concentration of crinoidal debris, pronounced lateral changes in thickness and lithofacies, and a largely endemic fusulinid fauna. Most outcrops represent a carbonate platform and debris derived from it and shed downslope, but another group of outcrops represents one or possibly more isolated carbonate buildups that developed offshore from the platform. Tectonic activity in the area occurred before, probably during, and after deposition of this short-lived carbonate complex.

  19. Designing using manufacturing features

    Science.gov (United States)

    Szecsi, T.; Hoque, A. S. M.

    2012-04-01

    This paper presents a design system that enables the composition of a part using manufacturing features. Features are selected from feature libraries. Upon insertion, the system ensures that the feature does not contradict the design-for-manufacture rules. This helps eliminating costly manufacturing problems. The system is developed as an extension to a commercial CAD/CAM system Pro/Engineer.

  20. Perspectives on the Role and Synergies of Architecture and Social and Built Environment in Enabling Active Healthy Aging

    OpenAIRE

    Evangelia Chrysikou; Richard Rabnett; Chariklia Tziraki

    2016-01-01

    Research has demonstrated that enabling societal and physical infrastructure and personal accommodations enhance healthy and active aging throughout the lifespan. Yet, there is a paucity of research on how to bring together the various disciplines involved in a multidomain synergistic collaboration to create new living environments for aging. This paper aims to explore the key domains of skills and knowledge that need to be considered for a conceptual prototype of an enabling educational proc...

  1. INTEGRATED AUTOMOTIVE MANUFACTURING SUPPLY

    Directory of Open Access Journals (Sweden)

    P.J.S. Van Dyk

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: Supply planning and traffic flow planning are major activities in the automotive manufacturing environment worldwide. Traditionally, the impact of supply planning strategies on plant traffic is rarely considered. This paper describes the development of a Decision Support System (DSS that will assist automotive manufacturers to analyse the effect of supply planning decisions on plant traffic during the supply planning phase of their logistics planning process. In essence, this DSS consists of a Supply Medium Decision Support Tool (SMDST (an interactive MS-Excel model with Visual Basic interfacing and a traffic flow simulation model tool (using eMPlant simulation software.

    AFRIKAANSE OPSOMMING: Verskaffingsbeplanning en verkeersvloeibeplanning is belangrike aktiwiteite in die motorvervaardigingsbedryf wêreldwyd. Tradisioneel word die uitwerking van verskaffings-beplanningsstrategië op aanlegverkeer selde in ag geneem. Hierdie artikel beskryf die ontwikkeling van ’n Besluitnemings Ondersteuningstelsel (DSS wat motorvervaardigers sal ondersteun in die analise van die effek van verskaffingsbeplanningbesluite op aanlegverkeer tydens die verskaffingsbeplanningsfase van hulle logistieke beplanningsproses. Hierdie DSS bestaan hoofsaaklik uit ’n Verskaffings-vervoermiddel Besluitnemingshulpmiddel (SMDST (’n interaktiewe MS-Excel model met “Visual Basic” koppelling asook ’n simulasiemodel van verkeersvloei (met eM-Plant simulasiesagteware.

  2. Perspectives on the Role and Synergies of Architecture and Social and Built Environment in Enabling Active Healthy Aging

    Directory of Open Access Journals (Sweden)

    Evangelia Chrysikou

    2016-01-01

    Full Text Available Research has demonstrated that enabling societal and physical infrastructure and personal accommodations enhance healthy and active aging throughout the lifespan. Yet, there is a paucity of research on how to bring together the various disciplines involved in a multidomain synergistic collaboration to create new living environments for aging. This paper aims to explore the key domains of skills and knowledge that need to be considered for a conceptual prototype of an enabling educational process and environments where healthcare professionals, architects, planners, and entrepreneurs may establish a shared theoretical and experiential knowledge base, vocabulary, and implementation strategies, for the creation of the next generation of living communities of active healthy adults, for persons with disabilities and chronic disease conditions. We focus on synergistic, paradigmatic, simple, and practical issues that can be easily upscaled through market mechanisms. This practical and physically concrete approach may also become linked with more elaborate neuroscientific and technologically sophisticated interventions. We examine the domains of knowledge to be included in establishing a learning model that focuses on the still-understudied impact of the benefits toward active and healthy aging, where architects, urban planners, clinicians, and healthcare facility managers are educated toward a synergistic approach at the operational level.

  3. Perspectives on the Role and Synergies of Architecture and Social and Built Environment in Enabling Active Healthy Aging.

    Science.gov (United States)

    Chrysikou, Evangelia; Rabnett, Richard; Tziraki, Chariklia

    2016-01-01

    Research has demonstrated that enabling societal and physical infrastructure and personal accommodations enhance healthy and active aging throughout the lifespan. Yet, there is a paucity of research on how to bring together the various disciplines involved in a multidomain synergistic collaboration to create new living environments for aging. This paper aims to explore the key domains of skills and knowledge that need to be considered for a conceptual prototype of an enabling educational process and environments where healthcare professionals, architects, planners, and entrepreneurs may establish a shared theoretical and experiential knowledge base, vocabulary, and implementation strategies, for the creation of the next generation of living communities of active healthy adults, for persons with disabilities and chronic disease conditions. We focus on synergistic, paradigmatic, simple, and practical issues that can be easily upscaled through market mechanisms. This practical and physically concrete approach may also become linked with more elaborate neuroscientific and technologically sophisticated interventions. We examine the domains of knowledge to be included in establishing a learning model that focuses on the still-understudied impact of the benefits toward active and healthy aging, where architects, urban planners, clinicians, and healthcare facility managers are educated toward a synergistic approach at the operational level.

  4. Colloidal-based additive manufacturing of bio-inspired composites

    Science.gov (United States)

    Studart, Andre R.

    Composite materials in nature exhibit heterogeneous architectures that are tuned to fulfill the functional demands of the surrounding environment. Examples range from the cellulose-based organic structure of plants to highly mineralized collagen-based skeletal parts like bone and teeth. Because they are often utilized to combine opposing properties such as strength and low-density or stiffness and wear resistance, the heterogeneous architecture of natural materials can potentially address several of the technical limitations of artificial homogeneous composites. However, current man-made manufacturing technologies do not allow for the level of composition and fiber orientation control found in natural heterogeneous systems. In this talk, I will present two additive manufacturing technologies recently developed in our group to build composites with exquisite architectures only rivaled by structures made by living organisms in nature. Since the proposed techniques utilize colloidal suspensions as feedstock, understanding the physics underlying the stability, assembly and rheology of the printing inks is key to predict and control the architecture of manufactured parts. Our results will show that additive manufacturing routes offer a new exciting pathway for the fabrication of biologically-inspired composite materials with unprecedented architectures and functionalities.

  5. Security Considerations Based on PKI/CA in Manufacturing Grid

    Institute of Scientific and Technical Information of China (English)

    YIN Yong; LI Yu

    2006-01-01

    In the manufacturing grid environment, the span of the consideration of security issues is more extensive, and the solutions for them are more complex, therefore these problems in manufacturing grid can't longer be addressed by existing security technologies. In order to solve this problem, the paper first puts forward the security architecture of manufacturing grid on the basis of the proposal of the security strategies for manufacturing grid; then the paper introduces key technologies based on public key infrastructure-certificate authority (PKI/CA) to ensure the security of manufacturing grid, such as single sign-on, security proxy, independent authentication and so on. Schemes discussed in the paper have some values to settle security problems in the manufacturing grid environment.

  6. Advanced Manufacturing Technologies (AMT): Manufacturing Initiative Project

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA supports the Advanced Manufacturing National Program Office (AMNPO). Hosted by the National Institute of Standards and Technology (NIST) the AMNPO is...

  7. Brain architecture: A design for natural computation

    CERN Document Server

    Kaiser, Marcus

    2008-01-01

    Fifty years ago, John von Neumann compared the architecture of the brain with that of computers that he invented and which is still in use today. In those days, the organisation of computers was based on concepts of brain organisation. Here, we give an update on current results on the global organisation of neural systems. For neural systems, we outline how the spatial and topological architecture of neuronal and cortical networks facilitates robustness against failures, fast processing, and balanced network activation. Finally, we discuss mechanisms of self-organization for such architectures. After all, the organization of the brain might again inspire computer architecture.

  8. Landscape Architecture in Contemporary Danish Suburban Development

    DEFF Research Database (Denmark)

    Roden, Tina Maria

    2013-01-01

    design, it is argued that the current discourse of landscape urbanism needs to define itself more clearly in relation to the Danish landscape architecture tradition and more actively consider amenity and aesthetics. Via the discourse of landscape urbanism, landscape architecture in Danish suburban...... it became a theory, landscape urbanism has been common practice in European design projects. This implies that the urban challenges have been in the centre of landscape thought and practice for so long that Danish landscape architecture already includes urbanism. In order to recover momentum in Danish urban...... the indeterminacy of the future. KEYWORDS: Suburban development, landscape urbanism, landscape architecture, sustainability...

  9. Digital Aircraft Sheet Metal Part Manufacturing System and Its Key Technology

    Institute of Scientific and Technical Information of China (English)

    Wang; Junbiao; Liu; Chuang

    2007-01-01

    The architecture of digital sheet metal manufacturing system is proposed based on the classification of sheet metal manufacturing information.The essence of digital manufacturing is the definition,management and transfer of information,and the key technologies are brought forward and described.It is pointed out that knowledge-based manufacturing elements design is necessary to make digital technology efficient.The management of all kinds of sheet metal manufacturing element information is to build single source of manufacturing data.Multi-state model-based digital transfer and coordination method is designed to provide a foundation for digital manufacturing of aircraft sheet metal part.The application of digital sheet metal manufacturing is exemplified with an aircraft sheet metal part.The application result is compared to that of the traditional analog transfer technology.It is shown that the developed technology can improve part quality,shorten manufacturing time and lower manufacturing cost.

  10. Tectonic thinking in contemporary industrialized architecture

    Directory of Open Access Journals (Sweden)

    Anne

    2013-12-01

    Full Text Available Corresponding author: Professor Anne Beim, Ph.D., CINARK – Centre for Industrialized Architecture, Institute of Architectural Technology, The Royal Danish Academy of Fine Arts – School of Architecture, Phillip Langes ALlé 10, DK-1435 Copenhagen, Denmark. Tel.: +45 4170 1623; E-mail: anne.beim@kadk.dk This paper argues for a new critical approach to the ways architectural design strategies are developing. Contemporary construction industry appears to evolve into highly specialized and optimized processes driven by industrialized manufacturing, therefore the role of the architect and the understanding of the architectural design process ought to be revised. The paper is based on the following underlying hypothesis: ‘Tectonic thinking – defined as a central attention towards the nature, the properties, and the application of building materials (construction and how this attention forms a creative force in building constructions, structural features and architectural design (construing – helps to identify and refine technology transfer in contemporary industrialized building construction’. Through various references from the construction industry, business theory and architectural practice the paper offers various analyses, comparisons and concrete design approaches. How architectural design processes and the tectonic design can benefit from Integrated Product Deliveries, mass-customization and Design for Disassembly is examined and discussed. The paper concludes by presenting a series of arguments that call for adaptable systems based on sufficient numbers of industrialized building products of high quality and a great variety of suppliers, and point at the need for optimizing our use of resources in order to reach sustainable solutions in architecture.

  11. Structure of a Clostridium botulinum C143S thiaminase I/thiamin complex reveals active site architecture .

    Science.gov (United States)

    Sikowitz, Megan D; Shome, Brateen; Zhang, Yang; Begley, Tadhg P; Ealick, Steven E

    2013-11-05

    Thiaminases are responsible for the degradation of thiamin and its metabolites. Two classes of thiaminases have been identified based on their three-dimensional structures and their requirements for a nucleophilic second substrate. Although the reactions of several thiaminases have been characterized, the physiological role of thiamin degradation is not fully understood. We have determined the three-dimensional X-ray structure of an inactive C143S mutant of Clostridium botulinum (Cb) thiaminase I with bound thiamin at 2.2 Å resolution. The C143S/thiamin complex provides atomic level details of the orientation of thiamin upon binding to Cb-thiaminase I and the identity of active site residues involved in substrate binding and catalysis. The specific roles of active site residues were probed by using site directed mutagenesis and kinetic analyses, leading to a detailed mechanism for Cb-thiaminase I. The structure of Cb-thiaminase I is also compared to the functionally similar but structurally distinct thiaminase II.

  12. Rapid Response Manufacturing (RRM). Final CRADA report

    Energy Technology Data Exchange (ETDEWEB)

    Cain, W.D. [Lockheed Martin Energy Systems, Inc., Oak Ridge, TN (United States); Waddell, W.L. [National Centers for Manufacturing Sciences, Ann Arbor, MI (United States)

    1997-08-28

    A major accomplishment of the Rapid Response Manufacturing (RRM) project was the development of a broad-based generic framework for automating and integrating the design-to-manufacturing activities associated with machined part products. Key components of the framework are a manufacturing model that integrates product and process data in a consistent, minimally redundant manner, an advanced computer-aided engineering working environment, knowledge-based software systems for design, process planning, and manufacturing and new production technologies for making products directly from design application software.

  13. 4th Conference on Advances in architectural geometry 2014

    CERN Document Server

    Knippers, Jan; Mitra, Niloy; Wang, Wenping

    2015-01-01

    This book contains 24 technical papers presented at the fourth edition of the Advances in Architectural Geometry conference, AAG 2014, held in London, England, September 2014. It offers engineers, mathematicians, designers, and contractors insight into the efficient design, analysis, and manufacture of complex shapes, which will help open up new horizons for architecture. The book examines geometric aspects involved in architectural design, ranging from initial conception to final fabrication. It focuses on four key topics: applied geometry, architecture, computational design, and also practice in the form of case studies. In addition, the book also features algorithms, proposed implementation, experimental results, and illustrations. Overall, the book presents both theoretical and practical work linked to new geometrical developments in architecture. It gathers the diverse components of the contemporary architectural tendencies that push the building envelope towards free form in order to respond to multiple...

  14. Discussion on advanced manufacturing

    Institute of Scientific and Technical Information of China (English)

    WANG Xiankui

    2007-01-01

    Advanced manufacturing consists of continuity of manufacturing,its broad sense,and the core of the manufacturing process.The technology of continuous manufacturing is discussed according to both historical and modern perspectives.The relationship between human development and manufacturing technology is also discussed.Manufacturing is a continuously evolving topic.It is not only the foundation and means of imagination,conception,the science,and the technology of material change,but also the expression of national economy,national defense,and the support industries.The broad sense of manufacturing theory,which extends the concept of manufacturing,is an important development in the 20th century.The sense is analyzed in connection with design,material forming theory,synthesis of manufacturing technology,manufacturing modes,life cycle of product,hardware and sottware,and support environment,etc.At the same time,the core action and the development of the theory and technology of process is also discussed.At the end of this paper,the development directions of mechanical manufacturing science and technology are mentioned.

  15. Architecture of firm dynamic capabilities across inter-organizational activities: Explaining innovativeness in the context of nanotechnology

    Science.gov (United States)

    Petricevic, Olga

    In this dissertation I first develop a theoretical framework that explores different components of dynamic capabilities related to firm's boundary-spanning linkages across two different types of inter-organizational activities---alliances and networks. I argue that there are four different subsets of dynamic capabilities simultaneously at work: alliance opportunity-sensing, alliance opportunity-seizing, network opportunity-sensing and network opportunity-seizing. Furthermore, I argue that there are significant interaction effects between these distinctive subsets driving the firm's overall effectiveness in sensing and seizing of novel and innovative external opportunities. In order to explore potential interdependencies and draw distinctions among different dynamic capability subsets I integrate concepts from the two theoretical perspectives that often neglect the emphasis of the other---the dynamic capability view and the social network perspective. I then test the hypothesized relationships in the context of firms actively patenting in nanotechnology. Nanotechnology innovations are multidisciplinary in nature and require search and discovery across multiple inter-organizational, scientific, geographic, industry, or technological domains by a particular firm. The findings offer support for the conceptualizations of dynamic capabilities as consisting of distinct subsets of capabilities for the sensing and the seizing of external new-knowledge opportunities. The findings suggest that firm's innovativeness in an interdisciplinary scientific field such as nanotechnology is the function of the vector of multi-dimensional dynamic capabilities that are context-specific. Furthermore, the findings also suggest that there are inherent trade-offs embedded in different dimensions of dynamic capabilities when deployed across a wide range of inter-organizational relationships.

  16. Current information technology needs of small to medium sized apparel manufacturers and contractors

    Energy Technology Data Exchange (ETDEWEB)

    Wimple, C., LLNL

    1998-04-01

    This report documents recent efforts of the American Textile Partnership (AMTEX{sup TM}) Demand Activated Manufacturing Architecture (DAMA) Project to identify opportunities for cost effective enhanced information technology use by small to medium sized apparel manufacturers and contractors. Background on the AMTEX/DAMA project and objectives for the specific DAMA Small and Medium Enterprise (SME) effort are discussed in this section. The approach used to gather information about current opportunities or needs is outlined in Section 2 Approach, and relevant findings are identified and a brief analysis of the information gathered is presented in Section 3 Findings. Recommendations based on the analysis, are offered in Section 4 Recommendations, and plans are suggested for DAMA follow-on in Section 5 Future Plans. Trip reports for each of the companies visited are contained in Appendix E - Company Trip Reports. These individual reports contain the data upon which the analysis presented in Section 3 Findings is based.

  17. White paper on continuous bioprocessing. May 20-21, 2014 Continuous Manufacturing Symposium.

    Science.gov (United States)

    Konstantinov, Konstantin B; Cooney, Charles L

    2015-03-01

    There is a growing interest in realizing the benefits of continuous processing in biologics manufacturing, which is reflected by the significant number of industrial and academic researchers who are actively involved in the development of continuous bioprocessing systems. These efforts are further encouraged by guidance expressed in recent US FDA conference presentations. The advantages of continuous manufacturing include sustained operation with consistent product quality, reduced equipment size, high-volumetric productivity, streamlined process flow, low-process cycle times, and reduced capital and operating cost. This technology, however, poses challenges, which need to be addressed before routine implementation is considered. This paper, which is based on the available literature and input from a large number of reviewers, is intended to provide a consensus of the opportunities, technical needs, and strategic directions for continuous bioprocessing. The discussion is supported by several examples illustrating various architectures of continuous bioprocessing systems.

  18. The Rhetoric of Campus Architecture

    Science.gov (United States)

    Smith, Cynthia Duquette

    2016-01-01

    The group activity described in this article was originally designed for an upper-division undergraduate course on Rhetoric and Architecture, but would also be well suited for courses in Persuasion, Rhetorical Criticism, or Visual Rhetoric. Any undergraduate course related to communication and design (including Advertising) could make excellent…

  19. Architecture for Direct Model-to-Part CNC Manufacturing

    Directory of Open Access Journals (Sweden)

    Gilbert Poon

    2006-02-01

    Full Text Available In the traditional paradigm for Computer Numerical Control (CNC machining, tool paths are programmed offline from the CNC machine using the Computer-Aided Design (CAD model of the workpiece. The program is downloaded to the CNC controller and the part is then machined. Since a CAD model does not exist inside the CNC controller, it is unaware of the part to be machined and cannot predict or prevent errors. Not only is this paradigm labor intensive, it can lead to catastrophic damage if there are errors during machining. This paper presents a new concept for CNC machine control whereby a CAD model of the workpiece exists inside the controller and the tool positions are generated in real-time by the controller using the computer's graphics hardware without human intervention. The new concept was implemented on an experimental lathe machine specifically designed to machine complicated ornamental wood workpieces with a personal computer. An example workpiece was machined and measured using a 3D camera. The measured data was registered to the CAD model to evaluate machining accuracy.

  20. Nanoscale topographical replication of graphene architecture by manufactured DNA nanostructures

    Science.gov (United States)

    Moon, Youngkwon; Shin, Jihoon; Seo, Soonbeom; Park, Sung Ha; Ahn, Joung Real

    2015-03-01

    Despite many studies on how geometry can be used to control the electronic properties of graphene, certain limitations to fabrication of designed graphene nanostructures exist. Here, we demonstrate controlled topographical replication of graphene by artificial deoxyribonucleic acid (DNA) nanostructures. Owing to the high degree of geometrical freedom of DNA nanostructures, we controlled the nanoscale topography of graphene. The topography of graphene replicated from DNA nanostructures showed enhanced thermal stability and revealed an interesting negative temperature coefficient of sheet resistivity when underlying DNA nanostructures were denatured at high temperatures.

  1. Exporting Humanist Architecture

    DEFF Research Database (Denmark)

    Nielsen, Tom

    2016-01-01

    values and ethical stands involved in the export of Danish Architecture. Abstract: Danish architecture has, in a sense, been driven by an unwritten contract between the architects and the democratic state and its institutions. This contract may be viewed as an ethos – an architectural tradition...... with inherent aesthetic and moral values. Today, however, Danish architecture is also an export commodity. That raises questions, which should be debated as openly as possible. What does it mean for architecture and architects to practice in cultures and under political systems that do not use architecture...... as a way of generating humanism, freedom or equality? The essay outlines the background story, identifies a number of positions in relation to architecture exports and discusses some of the dilemmas that arise when Danish architecture is seen in an export perspective....

  2. Religious architecture: anthropological perspectives

    NARCIS (Netherlands)

    O. Verkaaik

    2013-01-01

    Religious Architecture: Anthropological Perspectives develops an anthropological perspective on modern religious architecture, including mosques, churches and synagogues. Borrowing from a range of theoretical perspectives on space-making and material religion, this volume looks at how religious buil

  3. Rhein-Ruhr architecture

    DEFF Research Database (Denmark)

    2002-01-01

    katalog til udstillingen 'Rhein - Ruhr architecture' Meldahls smedie, 15. marts - 28. april 2002. 99 sider......katalog til udstillingen 'Rhein - Ruhr architecture' Meldahls smedie, 15. marts - 28. april 2002. 99 sider...

  4. Architectural Qualities in Passive Houses

    DEFF Research Database (Denmark)

    Brunsgaard, Camilla

    2012-01-01

    In recent years in Denmark there has been an increasing focus on implementing passive and active strategies in buildings to fulfil low energy demands like for example the Passive House Standard. From a technical rational perspective, plenty of pilot projects and commercial projects have shown...... that it is possible to build this type of houses, but the knowledge and discussion about the architectural quality in the buildings is hardly present. The question is if the strategies for optimising energy use and indoor environment collide with the architectural qualities of buildings. This paper brings forth...

  5. Research on Cost Index of Working Procedure in Manufacturing Process Based on Activity-Based Costing%基于作业成本法的制造过程工序成本指标研究

    Institute of Scientific and Technical Information of China (English)

    解德凤; 王慧; 付秀丽; 聂金宁

    2011-01-01

    In order to control the quality cost of manufacturing process effectively, it proposes the method of cost index of working procedure based on activity - based costing. Taking the manufacturing process of transmission shaft in heavy duty machine tools enterprise as an example, it uses activity- based costing theory to distribute the loss cost of manufacturing process among the working procedures, formulates the maximum allowable quality loss index of working procedure. The results show that working procedure cost index can play an important part in improving the qualified rate of product, reducing the mass loss and quality cost of manufacturing process.%为给制造过程质量成本控制提供有效依据,提出了基于作业成本法的工序成本指标研究方法.以某重型机床制造企业一批传动轴的加工过程为例,采用作业成本法理论,将制造过程产生的损失费用分配到各工序,制定各工序最大允许质量损失指标.结果表明,工序成本指标研究对降低制造过程质量损失率、提高产品合格率、降低质量成本具有一定的指导作用.

  6. Functional Architecture of Noise Correlations in Human Early Visual Cortex and its Relationship with Coherent Spontaneous Activity

    Directory of Open Access Journals (Sweden)

    Jungwon Ryu

    2012-10-01

    Full Text Available Responses of single sensory neurons to stimuli are ‘noisy’, varying substantially across repeated trials of identical stimulation. Intriguingly, these individual ‘noise responses’ (NR—deviations from their means—are not isolated; rather they are highly correlated, referred to as ‘noise correlation’ (NC. From a computational viewpoint, the presence and nature of NC exert great impacts on the information processing capacity of neurons as they encode sensory events as a population, decode those encoded neural responses, and contribute to perceptual choices for action. Regarding the origin of NR, on the other hand, there has been growing evidence pointing to its tight linkage with ‘spontaneous responses’ (SR—fluctuations of neural activity in the absence of external input or tasks. To investigate the functional structure of NC and its relationship with ‘correlations in SR’ (SC, we defined population receptive fields (pRFs of unit volumes of gray matter (UV in human early visual cortex and computed NRs and SRs using fMRI. NC increased with an increasing degree of similarity in pRF tuning properties such as orientation, spatial frequency, and visuotopic position, particularly between UV pairs close in cortical distance. This ‘like-to-like’ structure of NC remained unaltered across scan runs with different stimuli, even among between-area UV pairs. SC was higher than NC, and its functional and temporal structures were quite similar to those of NC. Furthermore, the partial correlation analysis revealed that NC between a given pair of UVs was best predicted by their SC than by any other factors examined in the current study.

  7. Improved Large Aperture Collector Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    O' Rourke, Deven [Abengoa Solar LLC, Lakewood, CO (United States); Farr, Adrian [Abengoa Solar LLC, Lakewood, CO (United States)

    2015-12-01

    The parabolic trough is the most established CSP technology and carries a long history of design experimentation dating back to the 1970’s. This has led to relatively standardized collector architectures, a maturing global supply chain, and a fairly uniform cost reduction strategy. Abengoa has deployed more than 1,500MWe of CSP troughs across several countries and has built and tested full-scale prototypes of many R&D concepts. The latest trough R&D efforts involved efforts to internalize non-CSP industry experience including a preliminary DFMA principles review done with Boothroyd Dewhurst, a construction literature review by the Arizona State University School of Construction Management, and two more focused manufacturing engineering subcontracts done by Ricardo Inc. and the nonprofit Edison Welding Institute. The first two studies highlighted strong opportunities in lowering part count, standardizing components and fasteners, developing modular designs to support prefabrication and automation, and devising simple, error-proof manual assembly methods. These principles have delivered major new cost savings in otherwise “mature” products in analogous industries like automotive, truck trailer manufacture, metal building fabrication, and shipbuilding. For this reason, they were core in the design development of the SpaceTube® collector, and arguably key to its early successes. The latter two studies were applied specifically to the first-generation SpaceTube® design and were important in setting the direction of the present SolarMat project. These studies developed a methodology to analyze the costs of manufacture and assembly, and identify new tooling concepts for more efficient manufacture. Among the main opportunities identified in these studies were the automated mirror arm manufacturing concept and the need for a less infrastructure-intensive assembly line, both of which now form central pillars of the SolarMat project strategy. These new designs will be

  8. Architectural Knitted Surfaces

    DEFF Research Database (Denmark)

    Mossé, Aurélie

    2010-01-01

    WGSN reports from the Architectural Knitted Surfaces workshop recently held at ShenkarCollege of Engineering and Design, Tel Aviv, which offered a cutting-edge insight into interactive knitted surfaces. With the increasing role of smart textiles in architecture, the Architectural Knitted Surfaces...

  9. BIOLOGICAL NANOROBOT ARCHITECTURE FOR MEDICAL TARGET IDENTIFICATION

    Directory of Open Access Journals (Sweden)

    S. Paul and Dipti*

    2012-07-01

    Full Text Available This work has an innovative approach for the development of biological nanorobots with sensors for medicine. The biological nanorobots operate in a virtual environment based on random, thermal and chemical control techniques. The biological nanorobot architecture model has biological nano bioelectronics as the basis for manufacturing integrated system devices with embedded biological nano biosensors and actuators, which facilitates its application for medical target identification and drug delivery. The biological nanorobot interaction with the described workspace shows how these biological nanorobots detect the target area and supply the drug. Therefore, our work addresses the control and the architecture design for developing practical molecular machines. Advances in nanotechnology are enabling manufacturing nanosensors and actuators through nano bioelectronics and biologically inspired devices. Analysis of integrated system modeling is one important aspect for supporting nanotechnology in the fast development towards one of the most challenging new fields of science: molecular machines. The use of 3D simulation can provide interactive tools for addressing nanorobot choices on sensing, hardware architecture design, manufacturing approaches, and control methodology investigation.

  10. HyperForest: A high performance multi-processor architecture for real-time intelligent systems

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, P. Jr.; Rebeil, J.P. [Sandia National Labs., Albuquerque, NM (United States); Pollard, H. [Univ. of New Mexico, Albuquerque, NM (United States). Electrical Engineering and Computer Engineering Dept.

    1997-04-01

    Intelligent Systems are characterized by the intensive use of computer power. The computer revolution of the last few years is what has made possible the development of the first generation of Intelligent Systems. Software for second generation Intelligent Systems will be more complex and will require more powerful computing engines in order to meet real-time constraints imposed by new robots, sensors, and applications. A multiprocessor architecture was developed that merges the advantages of message-passing and shared-memory structures: expendability and real-time compliance. The HyperForest architecture will provide an expandable real-time computing platform for computationally intensive Intelligent Systems and open the doors for the application of these systems to more complex tasks in environmental restoration and cleanup projects, flexible manufacturing systems, and DOE`s own production and disassembly activities.

  11. The EPOS ICT Architecture

    Science.gov (United States)

    Jeffery, Keith; Harrison, Matt; Bailo, Daniele

    2016-04-01

    The EPOS-PP Project 2010-2014 proposed an architecture and demonstrated feasibility with a prototype. Requirements based on use cases were collected and an inventory of assets (e.g. datasets, software, users, computing resources, equipment/detectors, laboratory services) (RIDE) was developed. The architecture evolved through three stages of refinement with much consultation both with the EPOS community representing EPOS users and participants in geoscience and with the overall ICT community especially those working on research such as the RDA (Research Data Alliance) community. The architecture consists of a central ICS (Integrated Core Services) consisting of a portal and catalog, the latter providing to end-users a 'map' of all EPOS resources (datasets, software, users, computing, equipment/detectors etc.). ICS is extended to ICS-d (distributed ICS) for certain services (such as visualisation software services or Cloud computing resources) and CES (Computational Earth Science) for specific simulation or analytical processing. ICS also communicates with TCS (Thematic Core Services) which represent European-wide portals to national and local assets, resources and services in the various specific domains (e.g. seismology, volcanology, geodesy) of EPOS. The EPOS-IP project 2015-2019 started October 2015. Two work-packages cover the ICT aspects; WP6 involves interaction with the TCS while WP7 concentrates on ICS including interoperation with ICS-d and CES offerings: in short the ICT architecture. Based on the experience and results of EPOS-PP the ICT team held a pre-meeting in July 2015 and set out a project plan. The first major activity involved requirements (re-)collection with use cases and also updating the inventory of assets held by the various TCS in EPOS. The RIDE database of assets is currently being converted to CERIF (Common European Research Information Format - an EU Recommendation to Member States) to provide the basis for the EPOS-IP ICS Catalog. In

  12. Information architecture. Volume 1, The foundations

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-03-01

    The Information Management Planning and Architecture Coordinating Team was formed to establish an information architecture framework to meet DOE`s current and future information needs. This department- wide activity was initiated in accordance with the DOE Information Management Strategic Plan; it also supports the Departmental Strategic Plan. It recognizes recent changes in emphasis as reflected in OMB Circular A-130 and the Information Resources Management Planning Process Improvement Team recommendations. Sections of this document provides the foundation for establishing DOE`s Information Architecture: Background, Business Case (reduced duplication of effort, increased integration of activities, improved operational capabilities), Baseline (technology baseline currently in place within DOE), Vision (guiding principles for future DOE Information Architecture), Standards Process, Policy and Process Integration (describes relations between information architecture and business processes), and Next Steps. Following each section is a scenario. A glossary of terms is provided.

  13. MEASURING MANUFACTURING INNOVATIVENESS

    DEFF Research Database (Denmark)

    Blichfeldt, Henrik; Knudsen, Mette Præst

    2017-01-01

    Globalization and customization increases the pressure on manufacturing companies, and the ability to provide innovativeness is a potential source of competitive advantage. This paper positions the manufacturing entity in the innovation process, and investigates the relation between innovation vers...... technology and organizational concepts. Based on Danish survey data from the European Manufacturing Survey (EMS-2015) this paper finds that there is a relation between innovative companies, and their level of technology and use of organizational concepts. Technology and organizational concepts act...... as manufacturing levers to support the manufacturing and production system to provide innovativeness. The managerial implication lies in building manufacturing capabilities to support the innovative process, by standardization, optimization and creating stability in combination with automation and advanced...

  14. Tectonic Thinking in Contemporary Industrialized Architecture

    Directory of Open Access Journals (Sweden)

    Anne Beim

    2013-12-01

    Full Text Available This paper argues for a new critical approach to the ways architectural design strategies are developing. Contemporary construction industry appears to evolve into highly specialized and optimized processes driven by industrialized manufacturing, therefore the role of the architect and the understanding of the architectural design process ought to be revised. The paper is based on the following underlying hypothesis: ‘Tectonic thinking – defined as a central attention towards the nature, the properties, and the application of building materials (construction and how this attention forms a creative force in building constructions, structural features and architectural design (construing – helps to identify and refine technology transfer in contemporary industrialized building construction’. (This definition of tectonic thinking forms part of a large, central research project: Towards a tectonic sustainable building practice, that is presently (2010- 2014 executed in collaboration between; The Royal Danish Academy of Fine Arts – School of Architecture, Aarhus School of Architecture, and The Danish Building Research Institute.Through various references from the construction industry, business theory and architectural practice the paper offers various analyses, comparisons and concrete design approaches. How architectural design processes and the tectonic design can benefit from Integrated Product Deliveries, mass-customization and Design for Disassembly is examined and discussed. The paper concludes by presenting a series of arguments that call for adaptable systems based on sufficient numbers of industrialized building products of high quality and a great variety of suppliers, and point at the need for optimizing our use of resources in order to reach sustainable solutions in architecture.

  15. Manufacturing Demonstration Facility (MDF)

    Data.gov (United States)

    Federal Laboratory Consortium — The U.S. Department of Energy Manufacturing Demonstration Facility (MDF) at Oak Ridge National Laboratory (ORNL) provides a collaborative, shared infrastructure to...

  16. Composite Structures Manufacturing Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Composite Structures Manufacturing Facility specializes in the design, analysis, fabrication and testing of advanced composite structures and materials for both...

  17. Advanced Manufacturing Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Manufacturing Laboratory at the University of Maryland provides the state of the art facilities for realizing next generation products and educating the...

  18. Software architecture evolution

    DEFF Research Database (Denmark)

    Barais, Olivier; Le Meur, Anne-Francoise; Duchien, Laurence

    2008-01-01

    Software architectures must frequently evolve to cope with changing requirements, and this evolution often implies integrating new concerns. Unfortunately, when the new concerns are crosscutting, existing architecture description languages provide little or no support for this kind of evolution....... The software architect must modify multiple elements of the architecture manually, which risks introducing inconsistencies. This chapter provides an overview, comparison and detailed treatment of the various state-of-the-art approaches to describing and evolving software architectures. Furthermore, we discuss...... one particular framework named Tran SAT, which addresses the above problems of software architecture evolution. Tran SAT provides a new element in the software architecture descriptions language, called an architectural aspect, for describing new concerns and their integration into an existing...

  19. A Technical and Business Perspective on Wireless Sensor Network for Manufacturing Execution System

    Directory of Open Access Journals (Sweden)

    Wei Xu

    2015-01-01

    Full Text Available Motivated by the complex production management with difficulties in error-prone assembly system and inaccurate supply chain inventory, this paper designs a novel manufacturing execution system (MES architecture for intelligent monitoring based on wireless sensor network (WSN. The technical perspective includes analysis on the proposed manufacturing resource mutual inductance method under active sensing network, appreciation technology of multisource information, and dynamic optimization technology for manufacturing execution processes. From business perspective, this paper elaborates the impact of RFID investment on complex product by establishing a three-stage supply chain model that involves two suppliers carrying out Stackelberg games (manufacturer and retailer. The optimal cost threshold values of technology investment are examined for both the centralized and the decentralized scenarios utilizing quantitative modeling methods. By analyzing and comparing the optimal profit with or without investment on WSN, this paper establishes a supply chain coordination and boosting model. The results of this paper have contributed significantly for one to make decision on whether RFID should be adopted among its members in supply chain. The system performance and model extension are verified via numerical analyses.

  20. Functional Biomimetic Architectures

    Science.gov (United States)

    Levine, Paul M.

    N-substituted glycine oligomers, or 'peptoids,' are a class of sequence--specific foldamers composed of tertiary amide linkages, engendering proteolytic stability and enhanced cellular permeability. Peptoids are notable for their facile synthesis, sequence diversity, and ability to fold into distinct secondary structures. In an effort to establish new functional peptoid architectures, we utilize the copper-catalyzed azide-alkyne [3+2] cycloaddition (CuAAC) reaction to generate peptidomimetic assemblies bearing bioactive ligands that specifically target and modulate Androgen Receptor (AR) activity, a major therapeutic target for prostate cancer. Additionally, we explore chemical ligation protocols to generate semi-synthetic hybrid biomacromolecules capable of exhibiting novel structures and functions not accessible to fully biosynthesized proteins.

  1. Innovative Teaching of IC Design and Manufacture Using the Superchip Platform

    Science.gov (United States)

    Wilson, P. R.; Wilcock, R.; McNally, I.; Swabey, M.

    2010-01-01

    This paper describes how an intelligent chip architecture has allowed a large cohort of undergraduate (UG) students to be given effective practical insight into integrated circuit (IC) design by designing and manufacturing their own ICs. To achieve this, an efficient chip architecture, the "Superchip," was developed, which allows multiple student…

  2. Insights into the 3D architecture of an active caldera ring-fault at Tendürek volcano through modeling of geodetic data

    KAUST Repository

    Vasyura-Bathke, Hannes

    2015-04-28

    The three-dimensional assessment of ring-fault geometries and kinematics at active caldera volcanoes is typically limited by sparse field, geodetic or seismological data, or by only partial ring-fault rupture or slip. Here we use a novel combination of spatially dense InSAR time-series data, numerical models and sand-box experiments to determine the three-dimensional geometry and kinematics of a sub-surface ring-fault at Tendürek volcano in Turkey. The InSAR data reveal that the area within the ring-fault not only subsides, but also shows substantial westward-directed lateral movement. The models and experiments explain this as a consequence of a ‘sliding-trapdoor’ ring-fault architecture that is mostly composed of outward-inclined reverse segments, most markedly so on the volcano\\'s western flanks but includes inward-inclined normal segments on its eastern flanks. Furthermore, the model ring-fault exhibits dextral and sinistral strike-slip components that are roughly bilaterally distributed onto its northern and southern segments, respectively. Our more complex numerical model describes the deformation at Tendürek better than an analytical solution for a single rectangular dislocation in a half-space. Comparison to ring-faults defined at Glen Coe, Fernandina and Bárðarbunga calderas suggests that ‘sliding-trapdoor’ ring-fault geometries may be common in nature and should therefore be considered in geological and geophysical interpretations of ring-faults at different scales worldwide.

  3. Modern manufacturing engineering

    CERN Document Server

    2015-01-01

    This book covers recent research and trends in Manufacturing Engineering. The chapters emphasize different aspects of the transformation from materials to products. It provides the reader with fundamental materials treatments and the integration of processes. Concepts such as green and lean manufacturing are also covered in this book.

  4. Retailer brand architectures: Consumer perceptions of five Danish food retailers

    DEFF Research Database (Denmark)

    Esbjerg, Lars; Grunert, Klaus G.; Juhl, Hans Jørn

    In this paper we adapt the concept of brand architecture to food retailing. We present initial findings of a study investigating how consumer perceive and evaluate the brand architectures of five different Danish food retailers. Our findings show that consumers perceive differences in the brand...... architecture of food retailers and that it is an important factor in relation to evaluations of food retailers. We also find that consumers have considerable difficulties distinguishing between retailer brands and manufacturer brands, which has potentially disconcerting implications for branded food...

  5. Manufacturing tolerant topology optimization

    DEFF Research Database (Denmark)

    Sigmund, Ole

    2009-01-01

    In this paper we present an extension of the topology optimization method to include uncertainties during the fabrication of macro, micro and nano structures. More specifically, we consider devices that are manufactured using processes which may result in (uniformly) too thin (eroded) or too thick...... (dilated) structures compared to the intended topology. Examples are MEMS devices manufactured using etching processes, nano-devices manufactured using e-beam lithography or laser micro-machining and macro structures manufactured using milling processes. In the suggested robust topology optimization...... that the method provides manufacturing tolerant designs with little decrease in performance. As a positive side effect the robust design formulation also eliminates the longstanding problem of one-node connected hinges in compliant mechanism design using topology optimization....

  6. Optimized manufacturable porous materials

    DEFF Research Database (Denmark)

    Andreassen, Erik; Andreasen, Casper Schousboe; Jensen, Jakob Søndergaard

    Topology optimization has been used to design two-dimensional material structures with specific elastic properties, but optimized designs of three-dimensional material structures are more scarsely seen. Partly because it requires more computational power, and partly because it is a major challenge...... to include manufacturing constraints in the optimization. This work focuses on incorporating the manufacturability into the optimization procedure, allowing the resulting material structure to be manufactured directly using rapid manufacturing techniques, such as selective laser melting/sintering (SLM....../S). The available manufacturing methods are best suited for porous materials (one constituent and void), but the optimization procedure can easily include more constituents. The elasticity tensor is found from one unit cell using the homogenization method together with a standard finite element (FE) discretization...

  7. Three-dimensional Biomimetic Technology: Novel Biorubber Creates Defined Micro- and Macro-scale Architectures in Collagen Hydrogels.

    Science.gov (United States)

    Rodriguez-Rivera, Veronica; Weidner, John W; Yost, Michael J

    2016-02-12

    Tissue scaffolds play a crucial role in the tissue regeneration process. The ideal scaffold must fulfill several requirements such as having proper composition, targeted modulus, and well-defined architectural features. Biomaterials that recapitulate the intrinsic architecture of in vivo tissue are vital for studying diseases as well as to facilitate the regeneration of lost and malformed soft tissue. A novel biofabrication technique was developed which combines state of the art imaging, three-dimensional (3D) printing, and selective enzymatic activity to create a new generation of biomaterials for research and clinical application. The developed material, Bovine Serum Albumin rubber, is reaction injected into a mold that upholds specific geometrical features. This sacrificial material allows the adequate transfer of architectural features to a natural scaffold material. The prototype consists of a 3D collagen scaffold with 4 and 3 mm channels that represent a branched architecture. This paper emphasizes the use of this biofabrication technique for the generation of natural constructs. This protocol utilizes a computer-aided software (CAD) to manufacture a solid mold which will be reaction injected with BSA rubber followed by the enzymatic digestion of the rubber, leaving its architectural features within the scaffold material.

  8. Component-based Control Software Design for Flexible Manufacturing System

    Institute of Scientific and Technical Information of China (English)

    周炳海; 奚立峰; 曹永上

    2003-01-01

    A new method that designs and implements the component-based distributed & hierarchical flexible manufacturing control software is described with a component concept in this paper. The proposed method takes aim at improving the flexibility and reliability of the control system. On the basis of describing the concepts of component-based software and the distributed object technology, the architecture of the component-based software of the control system is suggested with the Common Object Request Broker Architecture (CORBA). And then, we propose a design method for component-based distributed & hierarchical flexible manufacturing control system. Finally, to verify the software design method, a prototype flexible manufacturing control system software has been implemented in Orbix 2. 3c, VC++6.0 and has been tested in connection with the physical flexible ranufacturing shop at the WuXi Professional Institute.

  9. A TQCS-based Scheduling Approach for Manufacturing Grid

    Institute of Scientific and Technical Information of China (English)

    LIU Li-lan; YU Tao; CAO Hong-wu; SHI Zhan-bei

    2004-01-01

    With Open Grid Service Architecture (OGSA) as system framework, and Globus Toolkit3.0 (GT3) as developing tools, Manufacturing Grid (MG) is proposed in this research to realize resource sharing and collaborative working among manufacturing resources, and task scheduling is one of the most critical components in this system. Nevertheless, the Globus Resource Allocation Manager (GRAM) does not provide scheduling system by default, and traditional performance-guided or economy-guided schedulers cannot satisfy our needs in MG. So, in this paper, a TQCS (Time, Quality, Cost, Service)-based scheduling approach is presented and the corresponding scheduler (Manufacturing Grid Task Scheduler, MGTS) is implemented with the functions of Global Process Planning (GPP) analyzing, resource discovery, resource selection, AHP (Analytic Hierarchy Process)-based resource mapping, and fault-tolerant handling. Furthermore, the application architecture is depicted at the end of the paper to illustrate the utilization of our scheduler.

  10. Architecture humanitarian emergencies

    DEFF Research Database (Denmark)

    Gomez-Guillamon, Maria; Eskemose Andersen, Jørgen; Contreras, Jorge Lobos

    2013-01-01

    Introduced by scientific articles conserning architecture and human rights in light of cultures, emergencies, social equality and sustainability, democracy, economy, artistic development and science into architecture. Concluding in definition of needs for new roles, processes and education of arc......, Architettura di Alghero in Italy, Architecture and Design of Kocaeli University in Turkey, University of Aguascalientes in Mexico, Architectura y Urbanismo of University of Chile and Escuela de Architectura of Universidad Austral in Chile....

  11. IT Architecture For Dummies

    CERN Document Server

    Hausman, Kalani Kirk

    2010-01-01

    A solid introduction to the practices, plans, and skills required for developing a smart system architecture. Information architecture combines IT skills with business skills in order to align the IT structure of an organization with the mission, goals, and objectives of its business. This friendly introduction to IT architecture walks you through the myriad issues and complex decisions that many organizations face when setting up IT systems to work in sync with business procedures. Veteran IT professional and author Kirk Hausman explains the business value behind IT architecture and provides

  12. Towards a Media Architecture

    DEFF Research Database (Denmark)

    Ebsen, Tobias

    2010-01-01

    This text explores the concept of media architecture as a phenomenon of visual culture that describes the use of screen-technology in new spatial configurations in practices of architecture and art. I shall argue that this phenomenon is not necessarily a revolutionary new approach, but rather...... a result of conceptual changes in both modes visual representation and in expressions of architecture. These are changes the may be described as an evolution of ideas and consequent experiments that can be traced back to changes in the history of art and the various styles and ideologies of architecture....

  13. Grid Architecture 2

    Energy Technology Data Exchange (ETDEWEB)

    Taft, Jeffrey D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-01-01

    The report describes work done on Grid Architecture under the auspices of the Department of Electricity Office of Electricity Delivery and Reliability in 2015. As described in the first Grid Architecture report, the primary purpose of this work is to provide stakeholder insight about grid issues so as to enable superior decision making on their part. Doing this requires the creation of various work products, including oft-times complex diagrams, analyses, and explanations. This report provides architectural insights into several important grid topics and also describes work done to advance the science of Grid Architecture as well.

  14. Elements of Architecture

    DEFF Research Database (Denmark)

    Elements of Architecture explores new ways of engaging architecture in archaeology. It conceives of architecture both as the physical evidence of past societies and as existing beyond the physical environment, considering how people in the past have not just dwelled in buildings but have existed...... and affective impacts, of these material remains. The contributions in this volume investigate the way time, performance and movement, both physically and emotionally, are central aspects of understanding architectural assemblages. It is a book about the constellations of people, places and things that emerge...

  15. Development of Aluminum in Architecture

    Directory of Open Access Journals (Sweden)

    Prof. Phd. Vangjel Dunovski

    2016-04-01

    Full Text Available Generally speaking, the task of the architecture is to create suitable atmosphere for performing a certain function of the human being. Though today, the interior and exterior space are shaped with equal responsibility and seriousness, the interior ambient is the one in which man spends most of his time. A building as a closed space provides protection from outside climate and weather changes and provides necessary conditions for work and living no matter the outside weather and climate conditions, sounds and noises. The outside walls with the windows are the vital shell under whose protection many useful human activities take place. The evolution of the window is as old as the architecture itself. Since the beginnings of architecture, man has been working on developing the window. One of the features of that evolution of the window is a relation of the surface of the hole of the window towards the outside walls. The advancing of the technology had its influence over the range of capacity of the construction which on the other hand had its influence over the enlarging the window's dimensions. From this we conclude that windows and window openings were and still are important instrument of expressing in the architecture. Besides providing daylight and air in the rooms, the windows also are a visual contact with the nature and underline the role of the building as a human being habitat like no other element of the building.

  16. Additive manufacturing of polymer-derived ceramics.

    Science.gov (United States)

    Eckel, Zak C; Zhou, Chaoyin; Martin, John H; Jacobsen, Alan J; Carter, William B; Schaedler, Tobias A

    2016-01-01

    The extremely high melting point of many ceramics adds challenges to additive manufacturing as compared with metals and polymers. Because ceramics cannot be cast or machined easily, three-dimensional (3D) printing enables a big leap in geometrical flexibility. We report preceramic monomers that are cured with ultraviolet light in a stereolithography 3D printer or through a patterned mask, forming 3D polymer structures that can have complex shape and cellular architecture. These polymer structures can be pyrolyzed to a ceramic with uniform shrinkage and virtually no porosity. Silicon oxycarbide microlattice and honeycomb cellular materials fabricated with this approach exhibit higher strength than ceramic foams of similar density. Additive manufacturing of such materials is of interest for propulsion components, thermal protection systems, porous burners, microelectromechanical systems, and electronic device packaging.

  17. Additive manufacturing of biologically-inspired materials.

    Science.gov (United States)

    Studart, André R

    2016-01-21

    Additive manufacturing (AM) technologies offer an attractive pathway towards the fabrication of functional materials featuring complex heterogeneous architectures inspired by biological systems. In this paper, recent research on the use of AM approaches to program the local chemical composition, structure and properties of biologically-inspired materials is reviewed. A variety of structural motifs found in biological composites have been successfully emulated in synthetic systems using inkjet-based, direct-writing, stereolithography and slip casting technologies. The replication in synthetic systems of design principles underlying such structural motifs has enabled the fabrication of lightweight cellular materials, strong and tough composites, soft robots and autonomously shaping structures with unprecedented properties and functionalities. Pushing the current limits of AM technologies in future research should bring us closer to the manufacturing capabilities of living organisms, opening the way for the digital fabrication of advanced materials with superior performance, lower environmental impact and new functionalities.

  18. Additive manufacturing of polymer-derived ceramics

    Science.gov (United States)

    Eckel, Zak C.; Zhou, Chaoyin; Martin, John H.; Jacobsen, Alan J.; Carter, William B.; Schaedler, Tobias A.

    2016-01-01

    The extremely high melting point of many ceramics adds challenges to additive manufacturing as compared with metals and polymers. Because ceramics cannot be cast or machined easily, three-dimensional (3D) printing enables a big leap in geometrical flexibility. We report preceramic monomers that are cured with ultraviolet light in a stereolithography 3D printer or through a patterned mask, forming 3D polymer structures that can have complex shape and cellular architecture. These polymer structures can be pyrolyzed to a ceramic with uniform shrinkage and virtually no porosity. Silicon oxycarbide microlattice and honeycomb cellular materials fabricated with this approach exhibit higher strength than ceramic foams of similar density. Additive manufacturing of such materials is of interest for propulsion components, thermal protection systems, porous burners, microelectromechanical systems, and electronic device packaging.

  19. Competitive Manufacturing Dynamics

    DEFF Research Database (Denmark)

    Rymaszewska, Anna; Christensen, Irene; Karlsson, Christer

    The increasing complexity of business environments and the pressure for organizations on delivering new products faster while maintaining the superior quality of their products, has forced manufacturing organizations to rethink their operations. Managers responsible for manufacturing ramp-up need...... to constantly improve this process in terms of time to volume, according to predefined cost and quality measures. The importance of the success of this process can lead to a significant creation of competitive advantage. This paper addresses the challenges of the manufacturing ramp-up process in the context...

  20. Model & scale as conceptual devices in architectural representation

    NARCIS (Netherlands)

    Stellingwerff, M.C.; Koorstra, P.A.

    2013-01-01

    This year we celebrate the tenth anniversary of our Computer Aided Manufacturing laboratory (CAMlab, http://www.camlab-bk.nl). From the start we provide laser cutting, CNC-milling and 3D-print facilities for the students and the researchers at the Faculty of Architecture in Delft. Over the past ten

  1. 75 FR 80040 - Manufacturing Council

    Science.gov (United States)

    2010-12-21

    ... International Trade Administration Manufacturing Council AGENCY: International Trade Administration, U.S... Manufacturing Council. SUMMARY: On November 23, 2010, the Department of Commerce's International Trade... vacant position on the Manufacturing Council (Council). The November 23, 2010 notice provided that...

  2. 75 FR 30781 - Manufacturing Council

    Science.gov (United States)

    2010-06-02

    ... International Trade Administration Manufacturing Council AGENCY: International Trade Administration, U.S... Manufacturing Council. SUMMARY: On March 16, 2010, the Department of Commerce's International Trade... the Manufacturing Council (Council). The March 16, 2010 notice provided that all applications must...

  3. RESHORING IN MANUFACTURING AND SERVICES

    Directory of Open Access Journals (Sweden)

    Serghei MĂRGULESCU

    2014-05-01

    Full Text Available The extent of offshoring and outsourcing recorded in manufacturing and services in the last two decades has gradually eroded the advantage of the global arbitrage of labor costs. Along with other factors, this process began to change the options of international relocation of some companies that initially had adopted such a strategy, generating a reverse trend for returning in the country of origin of manufacturing and other activities. This process, called "reshoring," has recently started to gain some consistency. The trend is most notable in the sphere of production. In terms of business and IT services we cannot yet speak of a tangible start of the reshoring phenomenon, as it does in the sphere of production. Nevertheless we can see a slowdown in the offshoring of services and the emergence of new strategies in the field.

  4. Reshoring in Manufacturing and Services

    Directory of Open Access Journals (Sweden)

    SERGHEI MĂRGULESCU

    2014-05-01

    Full Text Available The extent of offshoring and outsourcing recorded in manufacturing and services in the last two decades has gradually eroded the advantage of the global arbitrage of labor costs. Along with other factors, this process began to change the options of international relocation of some companies that initially had adopted such a strategy, generating a reverse trend for returning in the country of origin of manufacturing and other activities. This process, called "reshoring" has recently started to gain some consistency. The trend is most notable in the sphere of production. In terms of business and IT services we cannot yet speak of a tangible start of the reshoring phenomenon, as it does in the sphere of production. Nevertheless we can see a slowdown in the offshoring of services and the emergence of new strategies in the field.

  5. On Detailing in Contemporary Architecture

    DEFF Research Database (Denmark)

    Kristensen, Claus; Kirkegaard, Poul Henning

    2010-01-01

    / tactility can blur the meaning of the architecture and turn it into an empty statement. The present paper will outline detailing in contemporary architecture and discuss the issue with respect to architectural quality. Architectural cases considered as sublime piece of architecture will be presented...

  6. An Embodied Architecture

    Directory of Open Access Journals (Sweden)

    Frances Downing

    2012-10-01

    Full Text Available An architecture of the body is emerging out of theories of biology, complexity, and systems through the use of an evolving organism as its metaphor. Autopoiesis is the term used by biologists to describe the realm of existence for a living organism as it slides between the interchange of structure and information. Incoming information is filtered through the organism for its usefulness in the art of staying alive. Structural or organizational changes evolve as the organism adjusts to new information. To remain a viable organism—to survive—means that an entity must keep evolving without surrendering identity. Humans must maintain an embodied identity, often referred to as an organized self (Maturana & Varela, 1980, 1987, while viably exchanging information with other entities and the environment. This operation creates a topological boundary across which the communication takes place. Cognitive theorists and researchers have proposed that the animal condition is one of Embodied Realism; that is, animals such as we humans, are embodied, using our bodies to create basic metaphors, and, that we do this in a“real” world. The role of cognition in this equation is to allow humans the use of embodiment to explore abstract ideas through metaphor—such as “grasping an idea” (Lakoff &Johnson, 2003. In doing so, it allows the invention of an evolving language that refers to things “outside” our skin,like other entities and places. Autopoiesis describes the activities at the “edge” or boundary of an organism. The linguistic act can, therefore, be identified as fundamental medium for communication in the edge, between inside and outside, that assures the autopoiesis of place.In our own bodies, flesh is the biological manifest of the edge or boundary condition. Our understanding of flesh is that it is another of our organs; and at the same time, all organs are also bounded by flesh. It serves as a porous filter, delicate and complicated

  7. MEDICAL MANUFACTURING INNOVATIONS

    Directory of Open Access Journals (Sweden)

    Cosma Sorin Cosmin

    2015-02-01

    Full Text Available The purpose of these studies was to improve the design and manufacturing process by selective laser melting, of new medical implants. After manufacturing process, the implants were measured, microscopically and mechanical analyzed. Implants manufactured by AM can be an attractive option for surface coatings to improve the osseointegration process. The main advantages of customized implants made by AM process are: the precise adaptation to the region of implantation, better cosmesis, reduced surgical times and better performance over their generic counterparts. These medical manufacturing changes the way that the surgeons are planning surgeries and engineers are designing custom implant. AM process has eliminated the constraints of shape, size, internal structure and mechanical properties making it possible for fabrication of implants that conform to the physical and mechanical requirements of implantation according to CT images. This article will review some custom implants fabricated in DME using biocompatible titanium.

  8. Manufacturing parabolic mirrors

    CERN Multimedia

    1975-01-01

    The photo shows the construction of a vertical centrifuge mounted on an air cushion, with a precision of 1/10000 during rotation, used for the manufacture of very high=precision parabolic mirrors. (See Annual Report 1974.)

  9. Many Manufactured Nanosats Project

    Data.gov (United States)

    National Aeronautics and Space Administration — To achieve the capability to affordably produce scores of nano-spacecraft for envisioned constellation missions, a new manufacturing process is needed to reduce the...

  10. 基于制造业的高职职业英语第二课堂教学研究%A Study on the Teaching Strategies of EOP in Extracurricular Activities Based on Manufacturing in Vocational Colleges

    Institute of Scientific and Technical Information of China (English)

    张妍

    2014-01-01

    Manufacturing is the basic industry of national defense as well as economic progress. Under the backgrounds of dynamization, customization and globalization, manufacturing and services have an increasingly closer relationship in development. Improving service quality plays a vital role in manufacturing in China,and EOP in extracurricular activities is one of the necessary media to realize the goal. Vocational colleges located in Northeast China are obliged to do researches for achieving the aim of“Made in China”in the servitization of manufacturing. This paper studies on the main idea of EOP,the present state of English extracurricular activities, and the teaching strategies of EOP in extracurricular activities on the basis of manufacturing and modern service consciousness including local features, industry trend,contest participation,teacher-student relationship,ability development and guarantee mechanism.%制造业是国防建设和经济发展的基础产业。在全球顾客需求动态化、定制化、国际化背景下,制造业与服务业日趋融合发展,提高服务质量对于我国制造业至关重要,而职业英语(EOP)第二课堂是实现这一愿景的必要载体。东北地区的高职院校有责任探索在服务化转型的过程中成就“中国制造”的方略。通过分析EOP内涵,结合高职第二课堂开展现状,从地域特征、行业走向、以赛促学、师生角色、能力养成、保障机制等方面研究基于制造业且具有现代服务意识的高职EOP第二课堂教学策略。

  11. Additively Manufactured Propulsion System

    OpenAIRE

    Dushku, Matthew; Mueller, Paul

    2012-01-01

    New high-performance, carbon-fiber reinforced polymer material allows additive manufacturing to produce pressure vessels capable of high pressures (thousands of pounds per square inch). This advancement in turn allows integral hybrid propulsion which is revolutionary for both CubeSats and additively-manufactured spacecraft. Hybrid propulsion offers simplicity as compared to bipropellant liquid propulsion, significantly better safety compared to solid or monopropellant hydrazine propulsion, an...

  12. Plasma-aided manufacturing

    Science.gov (United States)

    Shohet, J. L.

    1993-12-01

    Plasma-aided manufacturing is used for producing new materials with unusual and superior properties, for developing new chemical compounds and processes, for machining, and for altering and refining materials and surfaces. Plasma-aided manufacturing has direct applications to semiconductor fabrication, materials synthesis, welding, lighting, polymers, anti-corrosion coatings, machine tools, metallurgy, electrical and electronics devices, hazardous waste removal, high performance ceramics, and many other items in both the high-technology and the more traditional industries in the United States.

  13. Workflow automation architecture standard

    Energy Technology Data Exchange (ETDEWEB)

    Moshofsky, R.P.; Rohen, W.T. [Boeing Computer Services Co., Richland, WA (United States)

    1994-11-14

    This document presents an architectural standard for application of workflow automation technology. The standard includes a functional architecture, process for developing an automated workflow system for a work group, functional and collateral specifications for workflow automation, and results of a proof of concept prototype.

  14. Architecture and Stages

    DEFF Research Database (Denmark)

    Kiib, Hans

    2009-01-01

    as "experiencescape" - a space between tourism, culture, learning and economy. Strategies related to these challenges involve new architectural concepts and art as ‘engines' for a change. New expressive architecture and old industrial buildings are often combined into hybrid narratives, linking the past...

  15. Aesthetics of sustainable architecture

    NARCIS (Netherlands)

    Lee, S.

    2011-01-01

    The purpose of this book is to reveal, explore and further the debate on the aesthetic potentials of sustainable architecture and its practice. This book opens a new area of scholarship and discourse in the design and production of sustainable architecture, one that is based in aesthetics. The chapt

  16. SMRF architecture concepts

    NARCIS (Netherlands)

    Rossum, W.L. van; Wit, J.J.M. de; Otten, M.P.G.; Huizing, A.G.

    2011-01-01

    This presents three valuable applications of scalable multifunction RF (SMRF) systems. These systems allow radar, ESM, and communication functionality using a single front-end architecture. With the use of a novel system design tool, concepts for SMRF architectures for airborne, ground-based and nav

  17. Architecture and energy

    DEFF Research Database (Denmark)

    Marsh, Rob; Lauring, Michael

    2011-01-01

    Traditional low-energy architecture has not necessarily led to reduced energy consumption. A paradigm shift is proposed promoting pluralistic energy-saving strategies.......Traditional low-energy architecture has not necessarily led to reduced energy consumption. A paradigm shift is proposed promoting pluralistic energy-saving strategies....

  18. Digitally-Driven Architecture

    Directory of Open Access Journals (Sweden)

    Henriette Bier

    2014-07-01

    Full Text Available The shift from mechanical to digital forces architects to reposition themselves: Architects generate digital information, which can be used not only in designing and fabricating building components but also in embedding behaviours into buildings. This implies that, similar to the way that industrial design and fabrication with its concepts of standardisation and serial production influenced modernist architecture, digital design and fabrication influences contemporary architecture. While standardisation focused on processes of rationalisation of form, mass-customisation as a new paradigm that replaces mass-production, addresses non-standard, complex, and flexible designs. Furthermore, knowledge about the designed object can be encoded in digital data pertaining not just to the geometry of a design but also to its physical or other behaviours within an environment. Digitally-driven architecture implies, therefore, not only digitally-designed and fabricated architecture, it also implies architecture – built form – that can be controlled, actuated, and animated by digital means.In this context, this sixth Footprint issue examines the influence of digital means as pragmatic and conceptual instruments for actuating architecture. The focus is not so much on computer-based systems for the development of architectural designs, but on architecture incorporating digital control, sens­ing, actuating, or other mechanisms that enable buildings to inter­act with their users and surroundings in real time in the real world through physical or sensory change and variation.

  19. Teaching American Indian Architecture.

    Science.gov (United States)

    Winchell, Dick

    1991-01-01

    Reviews "Native American Architecture," by Nabokov and Easton, an encyclopedic work that examines technology, climate, social structure, economics, religion, and history in relation to house design and the "meaning" of space among tribes of nine regions. Describes this book's use in a college course on Native American architecture. (SV)

  20. Software Architecture Evolution

    Science.gov (United States)

    Barnes, Jeffrey M.

    2013-01-01

    Many software systems eventually undergo changes to their basic architectural structure. Such changes may be prompted by new feature requests, new quality attribute requirements, changing technology, or other reasons. Whatever the causes, architecture evolution is commonplace in real-world software projects. Today's software architects, however,…

  1. Applying neuroscience to architecture.

    Science.gov (United States)

    Eberhard, John P

    2009-06-25

    Architectural practice and neuroscience research use our brains and minds in much the same way. However, the link between neuroscience knowledge and architectural design--with rare exceptions--has yet to be made. The concept of linking these two fields is a challenge worth considering.

  2. Energetics Manufacturing Technology Center (EMTC)

    Data.gov (United States)

    Federal Laboratory Consortium — The Energetics Manufacturing Technology Center (EMTC), established in 1994 by the Office of Naval Research (ONR) Manufacturing Technology (ManTech) Program, is Navy...

  3. New strategic roles of manufacturing

    DEFF Research Database (Denmark)

    Yang, Cheng; Johansen, John; Boer, Harry

    2008-01-01

    This paper aims to view manufacturing from a new angle, and tries to look beyond fit, focus and trade-offs, approaches which may no longer be sufficient for long-term competitive success. Four cases from different industries are described and used to illustrate and discuss the possibility...... of manufacturing playing new strategic roles. Backward, forward and lateral interactive support are suggested to explicate how manufacturing can realize its new strategic roles. Finally, four new strategic roles of manufacturing are suggested. They are: innovation manufacturing, ramp-up manufacturing, primary...... manufacturing, and service manufacturing....

  4. Architecture as liminal Space

    Directory of Open Access Journals (Sweden)

    Nilly Harag

    2015-11-01

    Full Text Available The point of departure of the architectural project has to stem from the combination of inner and outer journeys in between the real or imagined limits. The pressing challenge is to destabilize the neat division of architecture into separate bodies of knowledge and pose the architect’s mode of action on the threshold between the concrete and the universal. Architecture is a lens, an instrument one looks through to bring new perspectives into focus, enabling the transformation of experience from a magnified self-concentrated space to a wide horizon. Architecture narrates relations between spaces and examines its validity through signifying practices of design. Design for itself becomes the language of the current, of the immediate fashion. Architecture can fulfill peoples’ dreams and miraculously can provide them tools to invent new ones: Curiosity is the first motive to act.

  5. Can architecture be barbaric?

    Science.gov (United States)

    Hürol, Yonca

    2009-06-01

    The title of this article is adapted from Theodor W. Adorno's famous dictum: 'To write poetry after Auschwitz is barbaric.' After the catastrophic earthquake in Kocaeli, Turkey on the 17th of August 1999, in which more than 40,000 people died or were lost, Necdet Teymur, who was then the dean of the Faculty of Architecture of the Middle East Technical University, referred to Adorno in one of his 'earthquake poems' and asked: 'Is architecture possible after 17th of August?' The main objective of this article is to interpret Teymur's question in respect of its connection to Adorno's philosophy with a view to make a contribution to the politics and ethics of architecture in Turkey. Teymur's question helps in providing a new interpretation of a critical approach to architecture and architectural technology through Adorno's philosophy. The paper also presents a discussion of Adorno's dictum, which serves for a better understanding of its universality/particularity.

  6. Product Architecture Modularity Strategies

    DEFF Research Database (Denmark)

    Mikkola, Juliana Hsuan

    2003-01-01

    The focus of this paper is to integrate various perspectives on product architecture modularity into a general framework, and also to propose a way to measure the degree of modularization embedded in product architectures. Various trade-offs between modular and integral product architectures...... and how components and interfaces influence the degree of modularization are considered. In order to gain a better understanding of product architecture modularity as a strategy, a theoretical framework and propositions are drawn from various academic literature sources. Based on the literature review......, the following key elements of product architecture are identified: components (standard and new-to-the-firm), interfaces (standardization and specification), degree of coupling, and substitutability. A mathematical function, termed modularization function, is introduced to measure the degree of modularization...

  7. Architecture as Ars Combinatoria

    Directory of Open Access Journals (Sweden)

    Francesco Cacciatore

    2015-11-01

    Full Text Available Architecture today, no longer reflects the limits of experimentation and innovation. An extremely low-tech art whose field of possibilities consists of choosing and using that which has already been done in the past. It is because of this that the key skill a designer should have is the ability to recognize the complexity in forms around them: cities have the widest programming opportunities for architecture, in the two-way relationship that is established from the city that takes form in architecture and an architecture that finds its place in the contemporary city. Thus, architecture has its foundation in hospitality, an element that differentiates it significantly from the design.

  8. A Hierarchical Model Architecture for Enterprise Integration in Chemical Industries

    Institute of Scientific and Technical Information of China (English)

    华贲; 周章玉; 成思危

    2001-01-01

    Towards integration of supply chain, manufacturing/production and investment decision making, this paper presents a hierarchical model architecture which contains six sub-models covering the areas of manufacturing control, production operation, design and revamp, production management, supply chain and investment decision making. Six types of flow, material, energy, information, humanware, partsware and capital are ciasified. These flows connect enterprise components/subsystems to formulate system topology and logical structure. Enterprise components/subsystems are abstracted to generic elementary and composite classes. Finally, the model architecture is applied to a management system of an integrated suply chain, and suggestion are made on the usage of the model architecture and further development of the model as well as imvlementation issues.

  9. Minimalism in architecture: Abstract conceptualization of architecture

    Directory of Open Access Journals (Sweden)

    Vasilski Dragana

    2015-01-01

    Full Text Available Minimalism in architecture contains the idea of the minimum as a leading creative tend to be considered and interpreted in working through phenomena of empathy and abstraction. In the Western culture, the root of this idea is found in empathy of Wilhelm Worringer and abstraction of Kasimir Malevich. In his dissertation, 'Abstraction and Empathy' Worringer presented his thesis on the psychology of style through which he explained the two opposing basic forms: abstraction and empathy. His conclusion on empathy as a psychological basis of observation expression is significant due to the verbal congruence with contemporary minimalist expression. His intuition was enhenced furthermore by figure of Malevich. Abstraction, as an expression of inner unfettered inspiration, has played a crucial role in the development of modern art and architecture of the twentieth century. Abstraction, which is one of the basic methods of learning in psychology (separating relevant from irrelevant features, Carl Jung is used to discover ideas. Minimalism in architecture emphasizes the level of abstraction to which the individual functions are reduced. Different types of abstraction are present: in the form as well as function of the basic elements: walls and windows. The case study is an example of Sou Fujimoto who is unequivocal in its commitment to the autonomy of abstract conceptualization of architecture.

  10. Digital Architecture Planning Model

    Energy Technology Data Exchange (ETDEWEB)

    Oxstrand, Johanna Helene [Idaho National Lab. (INL), Idaho Falls, ID (United States). Light Water Reactor Sustainability Program (LWRS); Al Rashdan, Ahmad Yahya Mohammad [Idaho National Lab. (INL), Idaho Falls, ID (United States). Light Water Reactor Sustainability Program (LWRS); Bly, Aaron Douglas [Idaho National Lab. (INL), Idaho Falls, ID (United States). Light Water Reactor Sustainability Program (LWRS); Rice, Brandon Charles [Idaho National Lab. (INL), Idaho Falls, ID (United States). Light Water Reactor Sustainability Program (LWRS); Fitzgerald, Kirk [Idaho National Lab. (INL), Idaho Falls, ID (United States). Light Water Reactor Sustainability Program (LWRS); Wilson, Keith Leon [Idaho National Lab. (INL), Idaho Falls, ID (United States). Light Water Reactor Sustainability Program (LWRS)

    2016-03-01

    As part of the U.S. Department of Energy’s Light Water Reactor Sustainability Program, the Digital Architecture (DA) Project focuses on providing a model that nuclear utilities can refer to when planning deployment of advanced technologies. The digital architecture planning model (DAPM) is the methodology for mapping power plant operational and support activities into a DA that unifies all data sources needed by the utilities to operate their plants. The DA is defined as a collection of information technology capabilities needed to support and integrate a wide spectrum of real-time digital capabilities for performance improvements of nuclear power plants. DA can be thought of as integration of the separate instrumentation and control and information systems already in place in nuclear power plants, which are brought together for the purpose of creating new levels of automation in plant work activities. A major objective in DAPM development was to survey all key areas that needed to be reviewed in order for a utility to make knowledgeable decisions regarding needs and plans to implement a DA at the plant. The development was done in two steps. First, researchers surveyed the nuclear industry in order to learn their near-term plans for adopting new advanced capabilities and implementing a network (i.e., wireless and wire) infrastructure throughout the plant, including the power block. Secondly, a literature review covering regulatory documents, industry standards, and technical research reports and articles was conducted. The objective of the review was to identify key areas to be covered by the DAPM, which included the following: 1. The need for a DA and its benefits to the plant 2. Resources required to implement the DA 3. Challenges that need to be addressed and resolved to implement the DA 4. Roles and responsibilities of the DA implementation plan. The DAPM was developed based on results from the survey and the literature review. Model development, including

  11. Data-Centric Enterprise Architecture

    OpenAIRE

    Zeinab Rajabi; Maryam Nooraei Abade

    2012-01-01

    Enterprises choose Enterprise Architecture (EA) solution, in order to overcome dynamic business challenges and in coordinate various enterprise elements. In this article, a solution is suggested for the Enterprise Architecture development. The solution focuses on architecture data in the Enterprise Architecture development process. Data-centric architecture approach is preferred product-centric architecture approach. We suggest using Enterprise Ontology (EO) as context for collecting architec...

  12. Hybrid architecture: object, landscape, infrastructure

    OpenAIRE

    Pinto de Freitas, Rita

    2011-01-01

    The concept of "hybrid architecture" developed in this study considers hybrid all architecture that is at once object, landscape and infrastructure. Hybrid architecture, pushed by the fact that it concentrates in a single architectural intervention a triple object-, landscape- and infrastructure-related nature, generates architectural answers with very specific features, and its study achieves following goals: 1: Clarify the term hybrid related to architectural intervention; 2: Tran...

  13. Architectural view model for an integration platform

    Directory of Open Access Journals (Sweden)

    Tomasz Górski

    2012-03-01

    Full Text Available The most common architectural view model is "4+1" by Philipe Kruchten. This model presents the views required for a full description of computer system architecture. By contrast, this model seems to be insufficient to describe architecture of integration platform. Definitely lacks the view of integrated business processes. In the serviceoriented approach, one of the basic elements is a contract. It should also be included in the description of the architecture. Moreover, very important are integration mechanisms and mediation flows that should be presented in the description of architecture. Hence the need for integrated services view, and manner of their integration on the enterprise service bus. Use case view should also be extended by stereotypes required for presenting functionality exposed for other computer systems. It is therefore proposed architectural view model “1+5” for an integration platform. This model has following architectural views: Integrated processes, Use Cases, Logical, Integrated Services, Contracts, Deployment. Furthermore, in article was presented new UML profile "UML Profile for Integration Flows". In the profile were placed stereotypes corresponding to integration patterns and mediation mechanisms. It is important, that UML activity diagram was extended and its special form was obtained to model mediation flows on integration platform. Thus was proposed a new UML diagram: mediation flows diagram.

  14. Approaching Environmental Issues in Architecture

    DEFF Research Database (Denmark)

    Petersen, Mads Dines; Knudstrup, Mary-Ann

    2013-01-01

    The research presented here takes its point of departure in the design process with a specific focus on how it is approached when designing energy efficient architecture. This is done through a case-study of a design process in a Danish architectural office. This study shows the importance...... of having a clear strategy about how to work with optimizing the energy efficiency in the building from the first stages of the design process. It is not just a task that can be addressed by the engineers when a concept has been developed and approved by the client. It requires architects and engineers...... to address it from the beginning and work actively with it, but it also requires the client to state it clearly in the brief. From this study, it is evident that the work with energy efficiency requires us to focus on the formal framework for the design process. It must allow and support a multi...

  15. Utilizing Mass Customization Methods for Modular Manufacturing System Design

    DEFF Research Database (Denmark)

    Jørgensen, Steffen; Jacobsen, Alexia; Nielsen, Kjeld

    2011-01-01

    Markets today have become dynamic and demand rapid product changes, product variety, and customized products. In order to operate under and taking advantages of such conditions requires, amongst other aspects, manufacturing processes robust to product changes - a contradiction to traditional...... of Mass Customization (MC). Research focus has been on the basic principles and enabling technologies, while modular architectures and system design have received less attention. A potential to fill these gaps by applying selected design theories and methods of MC have been seen. Based on a communality...... manufacturing systems developed as dedicated engineer-to-order solutions, tailored to production of a specific product or a limited product assortment. In response, modular manufacturing concepts are evolving, which are aimed at possessing the needed responsiveness and aimed at being the manufacturing paradigm...

  16. Fractal Geometry of Architecture

    Science.gov (United States)

    Lorenz, Wolfgang E.

    In Fractals smaller parts and the whole are linked together. Fractals are self-similar, as those parts are, at least approximately, scaled-down copies of the rough whole. In architecture, such a concept has also been known for a long time. Not only architects of the twentieth century called for an overall idea that is mirrored in every single detail, but also Gothic cathedrals and Indian temples offer self-similarity. This study mainly focuses upon the question whether this concept of self-similarity makes architecture with fractal properties more diverse and interesting than Euclidean Modern architecture. The first part gives an introduction and explains Fractal properties in various natural and architectural objects, presenting the underlying structure by computer programmed renderings. In this connection, differences between the fractal, architectural concept and true, mathematical Fractals are worked out to become aware of limits. This is the basis for dealing with the problem whether fractal-like architecture, particularly facades, can be measured so that different designs can be compared with each other under the aspect of fractal properties. Finally the usability of the Box-Counting Method, an easy-to-use measurement method of Fractal Dimension is analyzed with regard to architecture.

  17. A new physical unclonable function architecture

    Science.gov (United States)

    Chuang, Bai; Xuecheng, Zou; Kui, Dai

    2015-03-01

    This paper describes a new silicon physical unclonable function (PUF) architecture that can be fabricated on a standard CMOS process. Our proposed architecture is built using process sensors, difference amplifier, comparator, voting mechanism and diffusion algorithm circuit. Multiple identical process sensors are fabricated on the same chip. Due to manufacturing process variations, each sensor produces slightly different physical characteristic values that can be compared in order to create a digital identification for the chip. The diffusion algorithm circuit ensures further that the PUF based on the proposed architecture is able to effectively identify a population of ICs. We also improve the stability of PUF design with respect to temporary environmental variations like temperature and supply voltage with the introduction of difference amplifier and voting mechanism. The PUF built on the proposed architecture is fabricated in 0.18 μm CMOS technology. Experimental results show that the PUF has a good output statistical characteristic of uniform distribution and a high stability of 98.1% with respect to temperature variation from -40 to 100 °C, and supply voltage variation from 1.7 to 1.9 V. Project supported by the National Natural Science Foundation of China (No. 61376031).

  18. Avionics Architecture for Exploration Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Avionics Architectures for Exploration Project team will develop a system level environment and architecture that will accommodate equipment from multiple...

  19. Integrated Data Assimilation Architecture Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Integrated Data Assimilation Architecture (IDAA) is a middleware architecture that facilitates the incorporation of heterogeneous sensing and control devices...

  20. Method for creating and visualizing product architectures

    DEFF Research Database (Denmark)

    Kvist, Morten; Pedersen, Rasmus; Mortensen, Niels Henrik

    2005-01-01

    presents a new method for synthesis and visualization of product architecture concepts. The visualization represents the concept from a market, product assortment and production/supply chain point of view in order to support the complex process of making the right decisions. The work is based...... on the assumption that a graphical overview of a given solution space and relations between market demands, product architecture and manufacturing layout can support decision-making and constitute a very powerful interaction between stakeholders in product development. The key feature of the method is two jigsaw....... The second is that several products can be developed from the same basis so that the company can base product families on the same basic set of design principles and technologies. The third is that modularization may support an alignment of market, product and production/supply chain aspects. This paper...

  1. Manufacturing tolerant topology optimization

    Institute of Scientific and Technical Information of China (English)

    Ole Sigmund

    2009-01-01

    In this paper we present an extension of the topology optimization method to include uncertainties during the fabrication of macro, micro and nano structures. More specifically, we consider devices that are manufactured using processes which may result in (uniformly) too thin (eroded)or too thick (dilated) structures compared to the intended topology. Examples are MEMS devices manufactured using etching processes, nano-devices manufactured using e-beam lithography or laser micro-machining and macro structures manufactured using milling processes. In the suggested robust topology optimization approach, under- and over-etching is modelled by image processing-based "erode" and "dilate" operators and the optimization problem is formulated as a worst case design problem. Applications of the method to the design of macro structures for minimum compliance and micro compliant mechanisms show that the method provides manufacturing tolerant designs with little decrease in performance. As a positive side effect the robust design formulation also eliminates the longstanding problem of one-node connected hinges in compliant mechanism design using topology optimization.

  2. Material and heat balance calculations for manufacturing of phosphoric acid activated carbon used in sugar refining%磷酸活化法制备糖用活性炭的物料和热量衡算

    Institute of Scientific and Technical Information of China (English)

    朱芸; 左宋林; 孙康; 许玉; 邓先伦

    2013-01-01

    按照目前磷酸活化杉木屑生产活性炭的常规工艺,分析并计算了年产1 500t糖用粉状活性炭生产的各个工序的物料和热量平衡.分析计算结果可以为磷酸活化法生产活性炭的工厂工艺设计、设备选型、能量消耗和成本核算提供基本依据,并可以为磷酸活化法工艺的改进和优化提供参考.%This paper calculated the material and heat balance of manufacturing phosphoric acid activated carbon used in sugar refining. The calculation was based on a conventional production line with Chinese fir sawdust as raw material and an annual capacity of 1 500 t. The results provided the fundamental data for process design, equipment selection, energy consumption evaluation and cost accounting of activated carbon manufacturing and helped optimizing the phosphoric acid activation process.

  3. RECONSTRUCTING DECONSTRUCTION IN ARCHITECTURE

    Directory of Open Access Journals (Sweden)

    IDHAM Noor Cholis

    2013-12-01

    Full Text Available This paper examines deconstruction in architecture and forms used, which triggered by dispute of form and its scientification claimed by deconstructivists. Deconstruction terminologyis studied in the first part related to architecture field as a base knowledge. Some sample works of known deconstructionist architects are assessed in order to understand how their building is deconstructed and what forms they used. Discussion about form and its relation to other fields is then pursued by discussing the involvement of terminology of science, aesthetic pattern, and human life. The results of this discussion give clear understanding how form related to deconstruction in architecture are used.

  4. ARCHITECTURE INFORMS HISTORY

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Clusters of ancient architecture in central China have recently been entered on the world heritage list A group of ancient architecture in Dengfeng,central China’s Henan Province,was added to the world heritage list at the 34th session of the World Heritage Committee in Brazil on August 1 this year.The architectural collection is China’s 39th property inscribed on the list,and the third world heritage site in the province after the Longmen Grottoes and Yinxu in Anyang,site of the capital of the late Shang Dynasty(1600-1046 B.C.).

  5. Adaptive Architectural Envelope

    DEFF Research Database (Denmark)

    Foged, Isak Worre; Kirkegaard, Poul Henning

    2010-01-01

    . The general scopes of this paper are to develop a new adaptive kinetic architectural structure, particularly a reconfigurable architectural structure which can transform body shape from planar geometries to hyper-surfaces using different control strategies, i.e. a transformation into more than one or two...... different shape alternatives. The adaptive structure is a proposal for a responsive building envelope which is an idea of a first level operational framework for present and future investigations towards performance based responsive architectures through a set of responsive typologies. A mock- up concept...

  6. Towards Adaptive Evolutionary Architecture

    DEFF Research Database (Denmark)

    Bak, Sebastian HOlt; Rask, Nina; Risi, Sebastian

    2016-01-01

    This paper presents first results from an interdisciplinary project, in which the fields of architecture, philosophy and artificial life are combined to explore possible futures of architecture. Through an interactive evolutionary installation, called EvoCurtain, we investigate aspects of how...... to the development of designs tailored to the individual preferences of inhabitants, changing the roles of architects and designers entirely. Architecture-as-it-could-be is a philosophical approach conducted through artistic methods to anticipate the technological futures of human-centered development within...

  7. Computer architecture technology trends

    CERN Document Server

    1991-01-01

    Please note this is a Short Discount publication. This year's edition of Computer Architecture Technology Trends analyses the trends which are taking place in the architecture of computing systems today. Due to the sheer number of different applications to which computers are being applied, there seems no end to the different adoptions which proliferate. There are, however, some underlying trends which appear. Decision makers should be aware of these trends when specifying architectures, particularly for future applications. This report is fully revised and updated and provides insight in

  8. Robust Manufacturing Control

    CERN Document Server

    2013-01-01

    This contributed volume collects research papers, presented at the CIRP Sponsored Conference Robust Manufacturing Control: Innovative and Interdisciplinary Approaches for Global Networks (RoMaC 2012, Jacobs University, Bremen, Germany, June 18th-20th 2012). These research papers present the latest developments and new ideas focusing on robust manufacturing control for global networks. Today, Global Production Networks (i.e. the nexus of interconnected material and information flows through which products and services are manufactured, assembled and distributed) are confronted with and expected to adapt to: sudden and unpredictable large-scale changes of important parameters which are occurring more and more frequently, event propagation in networks with high degree of interconnectivity which leads to unforeseen fluctuations, and non-equilibrium states which increasingly characterize daily business. These multi-scale changes deeply influence logistic target achievement and call for robust planning and control ...

  9. Architectures of prototypes and architectural prototyping

    DEFF Research Database (Denmark)

    Hansen, Klaus Marius; Christensen, Michael; Sandvad, Elmer;

    1998-01-01

    together as a team, but developed a prototype that more than fulfilled the expectations of the shipping company. The prototype should: - complete the first major phase within 10 weeks, - be highly vertical illustrating future work practice, - continuously live up to new requirements from prototyping...... sessions with users, - evolve over a long period of time to contain more functionality - allow for 6-7 developers working intensively in parallel. Explicit focus on the software architecture and letting the architecture evolve with the prototype played a major role in resolving these conflicting......This paper reports from experience obtained through development of a prototype of a global customer service system in a project involving a large shipping company and a university research group. The research group had no previous knowledge of the complex business of shipping and had never worked...

  10. "Advanced Manufacturing Methods for Systems of Nanospacecrafts".

    OpenAIRE

    Rochus, Pierre

    2014-01-01

    Space instrumentation and Space Environmental testing activities at CSL Dreams, a priori expectations and space specificities Advanced Manufacturing Techniques considered in our studies First steps realizations 15 years ago More concrete and more recent examples Conclusions and future activities Peer reviewed

  11. International transfer of manufacturing

    DEFF Research Database (Denmark)

    Petersen, Casper Landbo; Langkjær, Anna-Katrine Egsgaard; Larsen, René Toft

    2012-01-01

    From 2001 to 2007 Arla Foods, one of the largest dairy companies in the world has undergone a major Enterprise Architecture transformation involving organizational and technological changes. While the changes have been successful and the organization is enjoying a period of unprecedented success,...

  12. Design of Manufacturing Execution System for FMCG Industries

    Directory of Open Access Journals (Sweden)

    Arindam Banerjee

    2013-06-01

    Full Text Available Manufacturing Execution System (MES has been evolved as an effective solution for today’s high performance, mass production industrial automation system. MES acts like a bridge between managerial level ERP solution and shop floor level control systems hardwares. MES solutions are highly flexible which are developed and customized targeting some particular industry. In this paper we plan to design an MES architecture aiming FMCG (Fast Moving Consumer Goods industries. The proposed solution keeps the basic MES architecture intact while improves production data capturing process based on batch event detection approach. It also accelerates the 2-way communication between ERP and MES for exchanging batch production data.

  13. Strengthening the Competitiveness and Sustainability of a Semiconductor Manufacturer with Cloud Manufacturing

    Directory of Open Access Journals (Sweden)

    Toly Chen

    2014-01-01

    Full Text Available Cloud manufacturing (CMfg is a new-generation service-oriented networked manufacturing model that provides distributed users centralized managed manufacturing resources, ability, and services. CMfg is applied here to a semiconductor manufacturing factory. Benefits are classified into five aspects: cost savings, efficiency, additional data analysis capabilities, flexibility, and closer partner relationships. A strength, weakness, opportunity, and threat (SWOT analysis is done which guides a semiconductor manufacturer in planning CMfg implementation projects. Simulation of a wafer fabrication factory (wafer fab is used as an example. Several CMfg services are proposed for assisting the fab simulation activities through the collaboration of cloud service providers, software vendors, equipment suppliers, and the wafer fab. The connection with the competitiveness and sustainability of a wafer fab is also stressed.

  14. The brand architecture of grocery retailers

    DEFF Research Database (Denmark)

    Bech-Larsen, Tino; Esbjerg, Lars

    2009-01-01

    on these concepts has taken an internal management perspective on how retailers can manipulate aspects of the retail setting to serve their own interests. Then, we develop an alternative conceptualisation of retailer brand architecture that takes into account that consumers (and other constituents) are active co......This article discusses how the brand architecture of grocery retailers set material and symbolic boundaries for consumer choice, thus limiting consumer sovereignty. The article first discusses previous work on store atmospherics, servicescapes and brand architecture. It is argued that work based......- constructors of material and symbolic aspects of retail settings. It is discussed how consumers participate in constructing retailer brand architecture and how this concept differs from previous research. Implications for both research and practice are discussed....

  15. Localisation and World Modelling: an Architectural Perspective

    Directory of Open Access Journals (Sweden)

    Domenico G. Sorrenti

    2008-11-01

    Full Text Available Autonomous robot world modelling is a "chicken-and-egg" problem: position estimation needs a model of the world, whereas world modelling needs the robot position. Most of the works dealing with this issue propose holistic solutions under an algorithmic perspective by neglecting software architecture issues. This results in huge and monolithic pieces of software where implementation details reify strategic decisions. An architectural approach founded on separation of concerns may help to break the loop. Localisation and modelling, acting on different time scales, are mostly independent of each other. Sometimes synchronisation is required. Whenever needed, an external strategy tunes the relative rates of the two activities. The paper introduces rationale, design, and implementation of such a system which relies on Real-Time Performers, a software architecture providing suitable architectural abstractions to observe and control the system's temporal behaviour.

  16. Knowledge Management for Manufacturing

    Institute of Scientific and Technical Information of China (English)

    OveRustungHjelmervik; 王克胜; 袁庆丰; 方明伦

    2004-01-01

    Technology development and implementation on the manufacturing arena has, throughout the years, frustrated employees over the requirement of constantly adjusting to new technologies. The employee's ability to learn is bounded, and thus limited. Looking at a modern production system, it is often a complicated array of technologies that have to be coordinated; or the technologies are coordinating themselves through artificial intelligence. This paper discusses the need for a holistic knowledge management approach to manufacturing,combining in-place technology with process management philosophy, in order for the firm's human resources to create, share, store and apply new knowledge.

  17. Laser in manufacturing

    CERN Document Server

    Davim, J Paulo

    2013-01-01

    Generally a laser (light amplification by stimulated emission of radiation) is defined as "a device which uses a quantum mechanical effect, stimulated emission, to generate a coherent beam of light from a lasing medium of controlled purity, size, and shape". Laser material processing represents a great number of methods, which are rapidly growing in current and different industrial applications as new alternatives to traditional manufacturing processes. Nowadays, the use of lasers in manufacturing is an emerging area with a wide variety of applications, for example, in electronics, molds an

  18. Manufacturing and automation

    Directory of Open Access Journals (Sweden)

    Ernesto Córdoba Nieto

    2010-04-01

    Full Text Available The article presents concepts and definitions from different sources concerning automation. The work approaches automation by virtue of the author’s experience in manufacturing production; why and how automation prolects are embarked upon is considered. Technological reflection regarding the progressive advances or stages of automation in the production area is stressed. Coriat and Freyssenet’s thoughts about and approaches to the problem of automation and its current state are taken and examined, especially that referring to the problem’s relationship with reconciling the level of automation with the flexibility and productivity demanded by competitive, worldwide manufacturing.

  19. NASA Game Changing Development Program Manufacturing Innovation Project

    Science.gov (United States)

    Tolbert, Carol; Vickers, John

    2011-01-01

    This presentation examines the new NASA Manufacturing Innovation Project. The project is a part of the Game Changing Development Program which is one element of the Space Technology Programs Managed by Office of the Chief Technologist. The project includes innovative technologies in model-based manufacturing, digital additive manufacturing, and other next generation manufacturing tools. The project is also coupled with the larger federal initiatives in this area including the National Digital Engineering and Manufacturing Initiative and the Advanced Manufacturing Partnership. In addition to NASA, other interagency partners include the Department of Defense, Department of Commerce, NIST, Department of Energy, and the National Science Foundation. The development of game-changing manufacturing technologies are critical for NASA s mission of exploration, strengthening America s manufacturing competitiveness, and are highly related to current challenges in defense manufacturing activities. There is strong consensus across industry, academia, and government that the future competitiveness of U.S. industry will be determined, in large part, by a technologically advanced manufacturing sector. This presentation highlights the prospectus of next generation manufacturing technologies to the challenges faced NASA and by the Department of Defense. The project focuses on maturing innovative/high payoff model-based manufacturing technologies that may lead to entirely new approaches for a broad array of future NASA missions and solutions to significant national needs. Digital manufacturing and computer-integrated manufacturing "virtually" guarantee advantages in quality, speed, and cost and offer many long-term benefits across the entire product lifecycle. This paper addresses key enablers and emerging strategies in areas such as: Current government initiatives, Model-based manufacturing, and Additive manufacturing.

  20. Analysis of Architecture Pattern Usage in Legacy System Architecture Documentation

    NARCIS (Netherlands)

    Harrison, Neil B.; Avgeriou, Paris

    2008-01-01

    Architecture patterns are an important tool in architectural design. However, while many architecture patterns have been identified, there is little in-depth understanding of their actual use in software architectures. For instance, there is no overview of how many patterns are used per system or wh

  1. Robot Electronics Architecture

    Science.gov (United States)

    Garrett, Michael; Magnone, Lee; Aghazarian, Hrand; Baumgartner, Eric; Kennedy, Brett

    2008-01-01

    An electronics architecture has been developed to enable the rapid construction and testing of prototypes of robotic systems. This architecture is designed to be a research vehicle of great stability, reliability, and versatility. A system according to this architecture can easily be reconfigured (including expanded or contracted) to satisfy a variety of needs with respect to input, output, processing of data, sensing, actuation, and power. The architecture affords a variety of expandable input/output options that enable ready integration of instruments, actuators, sensors, and other devices as independent modular units. The separation of different electrical functions onto independent circuit boards facilitates the development of corresponding simple and modular software interfaces. As a result, both hardware and software can be made to expand or contract in modular fashion while expending a minimum of time and effort.

  2. Architecture for the senses

    DEFF Research Database (Denmark)

    Ryhl, Camilla

    2009-01-01

    findings from the PhD thesis 'A House for the Senses' by the author, a study of architectural requirements in housing design implied by a sensory impairment. The empirical research project is based on qualitative interviews and 1:1 testing in existing housing with participants who were either blind, deaf......Accommodating sensory disabilities in architectural design requires specific design considerations. These are different from the ones included by the existing design concept 'accessibility', which primarily accommodates physical disabilites. Hence a new design concept 'sensory accessbility......' is presented as a parallel and complementary concept to the existing one. Sensory accessiblity accommodates sensory disabilities and describes architectural design requirements needed to ensure access to to the sensory experiences and architectural quality of a given space. The article is based on research...

  3. DSP Architecture Design Essentials

    CERN Document Server

    Marković, Dejan

    2012-01-01

    In DSP Architecture Design Essentials, authors Dejan Marković and Robert W. Brodersen cover a key subject for the successful realization of DSP algorithms for communications, multimedia, and healthcare applications. The book addresses the need for DSP architecture design that maps advanced DSP algorithms to hardware in the most power- and area-efficient way. The key feature of this text is a design methodology based on a high-level design model that leads to hardware implementation with minimum power and area. The methodology includes algorithm-level considerations such as automated word-length reduction and intrinsic data properties that can be leveraged to reduce hardware complexity. From a high-level data-flow graph model, an architecture exploration methodology based on linear programming is used to create an array of architectural solutions tailored to the underlying hardware technology. The book is supplemented with online material: bibliography, design examples, CAD tutorials and custom software.

  4. Analyzing architecture articles

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    In the present study, we express the quality, function, and characteristics of architecture to help people comprehensively understand what architecture is. We also reveal the problems and conflict found in population, land, water resources, pollution, energy, and the organization systems in construction. China’s economy is transforming. We should focus on the cities, architectural environment, energy conservation, emission-reduction, and low-carbon output that will result in successful green development. We should macroscopically and microscopically analyze the development, from the natural environment to the artificial environment; from the relationship between human beings and nature to the combination of social ecology in cities, and farmlands. We must learn to develop and control them harmoniously and scientifically to provide a foundation for the methods used in architecture research.

  5. Ancient Chinese Architecture

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    CHINESE people have accu-mulated a great deal ofexperience in architecture,constantly improving building ma-terials and thus creating uniquebuilding styles.The history of ancient Chinesearchitechtural development can be

  6. Model Construct Based Enterprise Model Architecture and Its Modeling Approach

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    In order to support enterprise integration, a kind of model construct based enterprise model architecture and its modeling approach are studied in this paper. First, the structural makeup and internal relationships of enterprise model architecture are discussed. Then, the concept of reusable model construct (MC) which belongs to the control view and can help to derive other views is proposed. The modeling approach based on model construct consists of three steps, reference model architecture synthesis, enterprise model customization, system design and implementation. According to MC based modeling approach a case study with the background of one-kind-product machinery manufacturing enterprises is illustrated. It is shown that proposal model construct based enterprise model architecture and modeling approach are practical and efficient.

  7. A Frame Based Architecture for Information Integration in CIMS

    Institute of Scientific and Technical Information of China (English)

    吴信东

    1992-01-01

    This paper foumulates and architecture for information integration in computer integrated manufacturing systems(CIMS).The architecture takes the frame structure as single link among applications and between applications and physical storage.All the advantages in form features based intgrated systems can be found in the frame-based architecture as the frame structrue here takes from features as its primitives.But other advantage,e.g.,default knowledge and dynamic domain knowledge can be attached to frames and the frame structure is easy to be changed and extended,which cannot be found ing form reatures based systems,can also be showed in frame based architectures as the frame structure is a typical knowledge representation scheme in artificial intelligence and many researches and interests have put on it.

  8. Domain Specific Software Architecture for Design Center Automation

    CERN Document Server

    Sinha, Anshuman; Balakrishna, Vijaya

    2008-01-01

    Domain specific software architecture aims at software reuse through construction of domain architecture reference model. The constructed reference model presents a set of individual components and their interaction points. When starting on a new large software project, the design engineer starts with pre-constructed model, which can be easily browsed and picks up opportunities of use in the new solution design. This report discusses application of domain reference design methods by deriving domain specific reference architecture for a product ordering system in a design center. The product in this case is instock and special order blinds from different manufacturers in a large supply store. The development of mature domain specific reference software architecture for this domain is not the objective of this report. However, this report would like to capture the method used in one such process and that is the primary concern of this report. This report lists subjective details of such a process applied to the...

  9. ARCHITECTURE INFORMS HISTORY

    Institute of Scientific and Technical Information of China (English)

    ZAN JIFANG

    2010-01-01

    @@ Agroup of ancient architecture in Dengfeng, central China's Henan Province, was added to the world heritage list at the 34th session of the World Heritage Committee in Brazil on August 1 this year. The architectural col-lection is China's 39th property inscribed on the list, and the third world heritage site in the province after the Longmen Grottoes and Yinxu in Anyang, site of the capital of the late Shang Dynasty (1600-1046 B.C.).

  10. BioArchitecture

    OpenAIRE

    Gunning, Peter

    2012-01-01

    Volume 1 has defined the scope of BioArchitecture. From the outset we have strived to ensure that BioArchitecture is not limited to the three major polymer systems of the cytoplasm. I am happy to say that a cursory glance at the contents of volume 1 makes it clear that we are interested in all aspects of bioarchitecture from molecules to polymers to cells to tissue to the organism.

  11. Essential software architecture

    CERN Document Server

    Gorton, Ian

    2011-01-01

    Job titles like ""Technical Architect"" and ""Chief Architect"" nowadays abound in software industry, yet many people suspect that ""architecture"" is one of the most overused and least understood terms in professional software development. Gorton's book tries to resolve this dilemma. It concisely describes the essential elements of knowledge and key skills required to be a software architect. The explanations encompass the essentials of architecture thinking, practices, and supporting technologies. They range from a general understanding of structure and quality attributes through technical i

  12. Artificial cognition architectures

    CERN Document Server

    Crowder, James A; Friess, Shelli A

    2013-01-01

    The goal of this book is to establish the foundation, principles, theory, and concepts that are the backbone of real, autonomous Artificial Intelligence. Presented here are some basic human intelligence concepts framed for Artificial Intelligence systems. These include concepts like Metacognition and Metamemory, along with architectural constructs for Artificial Intelligence versions of human brain functions like the prefrontal cortex. Also presented are possible hardware and software architectures that lend themselves to learning, reasoning, and self-evolution

  13. Climate and architecture

    DEFF Research Database (Denmark)

    Tind Kristensen, Eva; Friis Møller, Winnie; Rotne, Georg

    2010-01-01

    Climate and Architecture analyserer klimaets rolle i arkitekturen. Intentionen med bogen er at pege på nogle af de mange muligheder for bygningers klimaregulering, som et mere detaljeret studie af de lokale klimatiske forhold og den stedlige byggeskik tilbyder.......Climate and Architecture analyserer klimaets rolle i arkitekturen. Intentionen med bogen er at pege på nogle af de mange muligheder for bygningers klimaregulering, som et mere detaljeret studie af de lokale klimatiske forhold og den stedlige byggeskik tilbyder....

  14. Greek architecture now

    DEFF Research Database (Denmark)

    Skousbøll, Karin Merete

    2006-01-01

    With the author's Scandinavian viewpoint the aim of this book has been an investigation into contemporary Greek architecture and at the same time providing an understanding for its essential characteristics based on the historic, cultural heritage of Hellas.......With the author's Scandinavian viewpoint the aim of this book has been an investigation into contemporary Greek architecture and at the same time providing an understanding for its essential characteristics based on the historic, cultural heritage of Hellas....

  15. 6th Workshop on Service Orientation in Holonic and Multi-Agent Manufacturing

    CERN Document Server

    Trentesaux, Damien; Thomas, André; Leitão, Paulo; Oliveira, José

    2017-01-01

    The book offers an integrated vision on Cloud and HPC, Big Data, Analytics and virtualization in computing-oriented manufacturing, combining information and communication technologies, service-oriented control of holonic architectures as well as enterprise integration solutions based on SOA principles. It is structured in eight parts, each one grouping research and trends in digital manufacturing and service oriented manufacturing control: Cloud and Cyber-Physical Systems for Smart Manufacturing, Reconfigurable and Self-organized Multi-Agent Systems for Industry and Service, Sustainability Issues in Intelligent Manufacturing Systems, Holonic and Multi-agent System Design for Industry and Service, Should Intelligent Manufacturing Systems be Dependable and Safe?, Service-oriented Management and Control of Manufacturing Systems, Engineering and Human Integration in Flexible and Reconfigurable Industrial Systems,Virtualization and Simulation in Computing-oriented Industry and Service.

  16. Approaching Technical Issues in Architectural Education

    DEFF Research Database (Denmark)

    Pugnale, Alberto; Parigi, Dario

    2012-01-01

    This paper discusses teaching of technical subjects in architecture, presenting two experimental activities, recently organized at Aalborg University - a two week long workshop and a one day long lecture. From the pedagogical point of view, the activities are strategically placed between...

  17. The NASA Integrated Information Technology Architecture

    Science.gov (United States)

    Baldridge, Tim

    1997-01-01

    This document defines an Information Technology Architecture for the National Aeronautics and Space Administration (NASA), where Information Technology (IT) refers to the hardware, software, standards, protocols and processes that enable the creation, manipulation, storage, organization and sharing of information. An architecture provides an itemization and definition of these IT structures, a view of the relationship of the structures to each other and, most importantly, an accessible view of the whole. It is a fundamental assumption of this document that a useful, interoperable and affordable IT environment is key to the execution of the core NASA scientific and project competencies and business practices. This Architecture represents the highest level system design and guideline for NASA IT related activities and has been created on the authority of the NASA Chief Information Officer (CIO) and will be maintained under the auspices of that office. It addresses all aspects of general purpose, research, administrative and scientific computing and networking throughout the NASA Agency and is applicable to all NASA administrative offices, projects, field centers and remote sites. Through the establishment of five Objectives and six Principles this Architecture provides a blueprint for all NASA IT service providers: civil service, contractor and outsourcer. The most significant of the Objectives and Principles are the commitment to customer-driven IT implementations and the commitment to a simpler, cost-efficient, standards-based, modular IT infrastructure. In order to ensure that the Architecture is presented and defined in the context of the mission, project and business goals of NASA, this Architecture consists of four layers in which each subsequent layer builds on the previous layer. They are: 1) the Business Architecture: the operational functions of the business, or Enterprise, 2) the Systems Architecture: the specific Enterprise activities within the context

  18. Additive Manufacturing: Making Imagination the Major Limitation

    Science.gov (United States)

    Zhai, Yuwei; Lados, Diana A.; LaGoy, Jane L.

    2014-05-01

    Additive manufacturing (AM) refers to an advanced technology used for the fabrication of three-dimensional near-net-shaped functional components directly from computer models, using unit materials. The fundamentals and working principle of AM offer several advantages, including near-net-shape capabilities, superior design and geometrical flexibility, innovative multi-material fabrication, reduced tooling and fixturing, shorter cycle time for design and manufacturing, instant local production at a global scale, and material, energy, and cost efficiency. Well suiting the requests of modern manufacturing climate, AM is viewed as the new industrial revolution, making its way into a continuously increasing number of industries, such as aerospace, defense, automotive, medical, architecture, art, jewelry, and food. This overview was created to relate the historical evolution of the AM technology to its state-of-the-art developments and emerging applications. Generic thoughts on the microstructural characteristics, properties, and performance of AM-fabricated materials will also be discussed, primarily related to metallic materials. This write-up will introduce the general reader to specifics of the AM field vis-à-vis advantages and common techniques, materials and properties, current applications, and future opportunities.

  19. Cladding tube manufacturing technology

    Energy Technology Data Exchange (ETDEWEB)

    Hahn, R. [Kraftwerk Union AG, Mulheim (Germany); Jeong, Y.H.; Baek, B.J.; Kim, K.H.; Kim, S.J.; Choi, B.K.; Kim, J.M. [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1999-04-01

    This report gives an overview of the manufacturing routine of PWR cladding tubes. The routine essentially consists of a series of deformation and annealing processes which are necessary to transform the ingot geometry to tube dimensions. By changing shape, microstructure and structure-related properties are altered simultaneously. First, a short overview of the basics of that part of deformation geometry is given which is related to tube reducing operations. Then those processes of the manufacturing routine which change the microstructure are depicted, and the influence of certain process parameters on microstructure and material properties are shown. The influence of the resulting microstructure on material properties is not discussed in detail, since it is described in my previous report 'Alloy Development for High Burnup Cladding.' Because of their paramount importance still up to now, and because manufacturing data and their influence on properties for other alloys are not so well established or published, the descriptions are mostly related to Zry4 tube manufacturing, and are only in short for other alloys. (author). 9 refs., 46 figs.

  20. Manufacturing halal in Malaysia

    DEFF Research Database (Denmark)

    Fischer, Johan

    2016-01-01

    production, trade and consumption. Based on fieldwork in Malaysia, this article explores how manufacturing companies understand and practise halal certification, standards and technoscience. I argue that while existing studies of halal overwhelmingly explore micro-social aspects such as the everyday...

  1. Reusing Old Manufacturing Buildings

    Science.gov (United States)

    Roman, Harry T.

    2014-01-01

    This article presents an interesting design challenge for students, one that will certainly let them integrate subject matter and get a sense of pride for doing something useful in their own community. The author would be willing to bet that the average town or city has some old red brick manufacturing building(s) that have seen much better days.…

  2. Manufacturer's Suggested Retail Prices

    NARCIS (Netherlands)

    Rosenkranz, S.

    2003-01-01

    Based on arguments of the `reference- dependent' theory of consumer choice we assume that a retailer's discount of a manufacturer's suggested retail price changes consumers' demand. We can show that the producer benefits from suggesting a retail price. If consumers are additionally sufficiently `los

  3. Drug development and manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Warner, Benjamin P.; McCleskey, T. Mark; Burrell, Anthony K.

    2015-10-13

    X-ray fluorescence (XRF) spectrometry has been used for detecting binding events and measuring binding selectivities between chemicals and receptors. XRF may also be used for estimating the therapeutic index of a chemical, for estimating the binding selectivity of a chemical versus chemical analogs, for measuring post-translational modifications of proteins, and for drug manufacturing.

  4. Time · Space · Architecture

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    In the 20th century a Swiss writer wrote a book titled Time, Space and Architecture, in which he discussed the relationship between architecture and the times. Fifty years after that, this paper adopts the same title, hoping to deepen the understanding of the space-time structure in architecture and contribute to the new exploration of architectural forms.

  5. Geometric Rationalization for Freeform Architecture

    KAUST Repository

    Jiang, Caigui

    2016-06-20

    The emergence of freeform architecture provides interesting geometric challenges with regards to the design and manufacturing of large-scale structures. To design these architectural structures, we have to consider two types of constraints. First, aesthetic constraints are important because the buildings have to be visually impressive. Sec- ond, functional constraints are important for the performance of a building and its e cient construction. This thesis contributes to the area of architectural geometry. Specifically, we are interested in the geometric rationalization of freeform architec- ture with the goal of combining aesthetic and functional constraints and construction requirements. Aesthetic requirements typically come from designers and architects. To obtain visually pleasing structures, they favor smoothness of the building shape, but also smoothness of the visible patterns on the surface. Functional requirements typically come from the engineers involved in the construction process. For exam- ple, covering freeform structures using planar panels is much cheaper than using non-planar ones. Further, constructed buildings have to be stable and should not collapse. In this thesis, we explore the geometric rationalization of freeform archi- tecture using four specific example problems inspired by real life applications. We achieve our results by developing optimization algorithms and a theoretical study of the underlying geometrical structure of the problems. The four example problems are the following: (1) The design of shading and lighting systems which are torsion-free structures with planar beams based on quad meshes. They satisfy the functionality requirements of preventing light from going inside a building as shad- ing systems or reflecting light into a building as lighting systems. (2) The Design of freeform honeycomb structures that are constructed based on hex-dominant meshes with a planar beam mounted along each edge. The beams intersect without

  6. New Energy Architecture. Myanmar

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-06-15

    A global transition towards a new energy architecture is under way, driven by countries' need to respond to the changing dynamics of economic growth, environmental sustainability and energy security. The World Economic Forum, in collaboration with Accenture, has created the New Energy Architecture Initiative to address and accelerate this transition. The Initiative supports the development of national strategies and policy frameworks as countries seek to achieve the combined goals of energy security and access, sustainability, and economic growth and development. The World Economic Forum has formed a partnership with the Ministry of Energy of Myanmar to help apply the Initiative's approach to this developing and resource-rich nation. The Asian Development Bank and the World Economic Forum's Project Adviser, Accenture, have collaborated with the Forum on this consultation process, and have been supported by relevant government, industry and civil society stakeholders. The consultation process aims to understand the nation's current energy architecture challenges and provide an overview of a path to a New Energy Architecture through a series of insights. These insights could form the basis for a long-term multistakeholder roadmap to build Myanmar's energy sector in a way that is secure and sustainable, and promotes economic growth as the country makes its democratic transition. While not all recommendations can be implemented in the near term, they do provide options for creating a prioritized roadmap for Myanmar's energy transition. This report is the culmination of a nine-month multistakeholder process investigating Myanmar's energy architecture. Over the course of many visits to the country, the team has conducted numerous interviews, multistakeholder workshops, and learning and data-gathering exercises to ensure a comprehensive range of information and views. The team has also engaged with a variety of stakeholders to better

  7. Service Orientation in Holonic and Multi-Agent Manufacturing Control

    CERN Document Server

    Thomas, André; Trentesaux, Damien

    2012-01-01

    Service orientation is emerging nowadays at multiple organizational levels in enterprise business, and it leverages technology in response to the growing need for greater business integration, flexibility and agility of manufacturing enterprises. This book gathers contributions from scientists, researchers and industrialists on concepts, methods, frameworks and implementing issues addressing trends in the service orientation of control technology and management applied to manufacturing enterprise. It analyzes a Service Oriented Architecture (SOA) representing a technical architecture, a business modelling concept, a type of infrastructure, an integration source and a new way of viewing units of automation within the enterprise. The presents how SOA aligns the business world with the world of information technology in a way that makes both more effective.  

  8. Configurable Enterprise: A New Trend in Manufacturing Enterprise Evolution

    Institute of Scientific and Technical Information of China (English)

    GU Yuanxun; GUO Jingjuan

    2006-01-01

    Along with the popularity of enterprise applications, the management reform of manufacturing enterprise (ME) relies on the business process reengineering is gradually invalid. Reviewing and comparison the former structure of different enterprise such as extend enterprise, virtual enterprise etc. from the perspective of link, unit, and focus. Through comparison the evolution of ME structure the configurable enterprise (CE) was put forward which based on the information and communication technology providing a new mechanism for the elements configuration and the resources allocation. Based on the reference model of enterprise business architecture, the framework of CE was raised, which includes enterprise business architecture, business model and component. Then modeling the dynamics of CE, the mechanism of key success factors interactions was analyzed and verified the key factors that de decided the evolution of CE which could forecast the development trend of manufacturing enterprise.

  9. Effect of Ceramic Scaffold Architectural Parameters on Biological Response

    Directory of Open Access Journals (Sweden)

    Maria Isabella eGariboldi

    2015-10-01

    Full Text Available Numerous studies have focused on the optimization of ceramic architectures to fulfill a variety of scaffold functional requirements and improve biological response. Conventional fabrication techniques, however, do not allow for the production of geometrically controlled, reproducible structures and often fail to allow the independent variation of individual geometric parameters. Current developments in additive manufacturing technologies suggest that 3D printing will allow a more controlled and systematic exploration of scaffold architectures. This more direct translation of design into structure requires a pipeline for design-driven optimization. A theoretical framework for systematic design and evaluation of architectural parameters on biological response is presented. Four levels of architecture are considered, namely (1 surface topography, (2 pore size and geometry, (3 porous networks and (4 macroscopic pore arrangement, including the potential for spatially varied architectures. Studies exploring the effect of various parameters within these levels are reviewed. This framework will hopefully allow uncovering of new relationships between architecture and biological response in a more systematic way, as well as inform future refinement of fabrication techniques to fulfill architectural necessities with a consideration of biological implications.

  10. Effect of Ceramic Scaffold Architectural Parameters on Biological Response.

    Science.gov (United States)

    Gariboldi, Maria Isabella; Best, Serena M

    2015-01-01

    Numerous studies have focused on the optimization of ceramic architectures to fulfill a variety of scaffold functional requirements and improve biological response. Conventional fabrication techniques, however, do not allow for the production of geometrically controlled, reproducible structures and often fail to allow the independent variation of individual geometric parameters. Current developments in additive manufacturing technologies suggest that 3D printing will allow a more controlled and systematic exploration of scaffold architectures. This more direct translation of design into structure requires a pipeline for design-driven optimization. A theoretical framework for systematic design and evaluation of architectural parameters on biological response is presented. Four levels of architecture are considered, namely (1) surface topography, (2) pore size and geometry, (3) porous networks, and (4) macroscopic pore arrangement, including the potential for spatially varied architectures. Studies exploring the effect of various parameters within these levels are reviewed. This framework will hopefully allow uncovering of new relationships between architecture and biological response in a more systematic way as well as inform future refinement of fabrication techniques to fulfill architectural necessities with a consideration of biological implications.

  11. DECOMPOSITION OF MANUFACTURING PROCESSES: A REVIEW

    Directory of Open Access Journals (Sweden)

    N.M.Z.N. Mohamed

    2012-06-01

    Full Text Available Manufacturing is a global activity that started during the industrial revolution in the late 19th century to cater for the large-scale production of products. Since then, manufacturing has changed tremendously through the innovations of technology, processes, materials, communication and transportation. The major challenge facing manufacturing is to produce more products using less material, less energy and less involvement of labour. To face these challenges, manufacturing companies must have a strategy and competitive priority in order for them to compete in a dynamic market. A review of the literature on the decomposition of manufacturing processes outlines three main processes, namely: high volume, medium volume and low volume. The decomposition shows that each sub process has its own characteristics and depends on the nature of the firm’s business. Two extreme processes are continuous line production (fast extreme and project shop (slow extreme. Other processes are in between these two extremes of the manufacturing spectrum. Process flow patterns become less complex with cellular, line and continuous flow compared with jobbing and project. The review also indicates that when the product is high variety and low volume, project or functional production is applied.

  12. Cellulose production, activated by cyclic di-GMP through BcsA and BcsZ, is a virulence factor and an essential determinant of the three-dimensional architectures of biofilms formed by Erwinia amylovora Ea1189.

    Science.gov (United States)

    Castiblanco, Luisa F; Sundin, George W

    2016-10-18

    Bacterial biofilms are multicellular aggregates encased in an extracellular matrix mainly composed of exopolysaccharides (EPSs), protein and nucleic acids, which determines the architecture of the biofilm. Erwinia amylovora Ea1189 forms a biofilm inside the xylem of its host, which results in vessel plugging and water transport impairment. The production of the EPSs amylovoran and levan is critical for the formation of a mature biofilm. In addition, cyclic dimeric GMP (c-di-GMP) has been reported to positively regulate amylovoran biosynthesis and biofilm formation in E. amylovora Ea1189. In this study, we demonstrate that cellulose is synthesized by E. amylovora Ea1189 and is a major modulator of the three-dimensional characteristics of biofilms formed by this bacterium, and also contributes to virulence during systemic host invasion. In addition, we demonstrate that the activation of cellulose biosynthesis in E. amylovora is a c-di-GMP-dependent process, through allosteric binding to the cellulose catalytic subunit BcsA. We also report that the endoglucanase BcsZ is a key player in c-di-GMP activation of cellulose biosynthesis. Our results provide evidence of the complex composition of the extracellular matrix produced by E. amylovora and the implications of cellulose biosynthesis in shaping the architecture of the biofilm and in the expression of one of the main virulence phenotypes of this pathogen.

  13. In-situ construction of Au nanoparticles confined in double-shelled TiO2/mSiO2 hollow architecture for excellent catalytic activity and enhanced thermal stability

    Science.gov (United States)

    Fang, Jiasheng; Zhang, Yiwei; Zhou, Yuming; Zhang, Chao; Zhao, Shuo; Zhang, Hongxing; Sheng, Xiaoli

    2017-01-01

    A facile strategy has been developed for the synthesis of H-TS-Au microspheres (MCs) with double-shelled hollow architecture and sub-5 nm Au nanoparticles (Au NPs). The synthetic procedure involves the successive sol-gel template-assisted method for the preparation of uniform hierarchical hollow-in-hollow H-TS MCs with TiO2/mSiO2 as yolks/shells, and the unique deposition-precipitation method mediated with Au(en)2Cl3 precursors for the in-situ construction of extremely stable Au NPs under a low-temperature hydrogen reduction. The synthesized H-TS-Au MCs were characterized by TEM, SEM, FTIR, XRD, BET and UV-vis absorption spectra. Catalytic activity of H-TS-Au was evaluated using the reduction of 4-nitrophenol (4-NP) into 4-aminophenol (4-AP) by NaBH4. Results established that H-TS-Au MCs possessed a large-size double-shelled architecture with high structural integrity and robustness,which can effectively confine numerous tiny Au NPs and restrict them from sintering aggregation even up to further calcination at 800 °C. Owing to the advantageous structural configuration and the synergistic effect of TiO2/mSiO2 double shells, the H-TS-Au MCs were demonstrated to exhibit a remarkable catalytic activity and stability, and preserve the intact morphology after 6 repeating reduction of 4-NP.

  14. Macromolecular architectures for organic photovoltaics.

    Science.gov (United States)

    Popere, Bhooshan C; Della Pelle, Andrea M; Poe, Ambata; Thayumanavan, S

    2012-03-28

    Research in the field of organic photovoltaics has gained considerable momentum in the last two decades owing to the need for developing low-cost and efficient energy harvesting systems. Elegant molecular architectures have been designed, synthesized and employed as active materials for photovoltaic devices thereby leading to a better molecular structure-device property relationship understanding. In this perspective, we outline new macromolecular scaffolds that have been designed within the purview of each of the three fundamental processes involving light harvesting, charge separation and charge transport.

  15. Hinge Dimension: An Exploration of Enaction in Architecture

    DEFF Research Database (Denmark)

    Franinovic, Karmen; Wilson, Alexander

    2007-01-01

    In this paper, we address issues of technologically mediated enactive experience with and within architectural contexts, and the ways in which it may affect our relationships to constructed surroundings. We present the conceptual ideas and design development of the Hinge Dimension project......, an interactive architecture which is activated and transformed though the actions of its inhabitants. Changing structural, sonic and luminous arrangements continuously produce different spatial experiences as visitors move though the architecture. We summarize the results that we gathered during the public...

  16. Bridging LSTM Architecture and the Neural Dynamics during Reading

    OpenAIRE

    Qian, Peng; Qiu, Xipeng; Huang, Xuanjing

    2016-01-01

    Recently, the long short-term memory neural network (LSTM) has attracted wide interest due to its success in many tasks. LSTM architecture consists of a memory cell and three gates, which looks similar to the neuronal networks in the brain. However, there still lacks the evidence of the cognitive plausibility of LSTM architecture as well as its working mechanism. In this paper, we study the cognitive plausibility of LSTM by aligning its internal architecture with the brain activity observed v...

  17. Globalization and Landscape Architecture

    Directory of Open Access Journals (Sweden)

    Robert R. Hewitt

    2014-02-01

    Full Text Available The literature review examines globalization and landscape architecture as discourse, samples its various meanings, and proposes methods to identify and contextualize its specific literature. Methodologically, the review surveys published articles and books by leading authors and within the WorldCat.org Database associated with landscape architecture and globalization, analyzing survey results for comprehensive conceptual and co-relational frameworks. Three “higher order” dimensions frame the review’s conceptual organization, facilitating the organization of subordinate/subtopical areas of interest useful for comparative analysis. Comparative analysis of the literature suggests an uneven clustering of discipline-related subject matter across the literature’s “higher order” dimensions, with a much smaller body of literature related to landscape architecture confined primarily to topics associated with the dispersion of global phenomena. A subcomponent of this smaller body of literature is associated with other fields of study, but inferentially related to landscape architecture. The review offers separate references and bibliographies for globalization literature in general and globalization and landscape architecture literature, specifically.

  18. Mobile Agent PLM Architecture for extended enterprise

    Directory of Open Access Journals (Sweden)

    Abdelhak Boulaalam

    2011-01-01

    Full Text Available Nowadays manufacturers are under increased pressure to have an add value for their products to struggle the low-cost production in emerging countries. Distributed control and Intelligent Product are a new and exciting opportunity to build more effective process networks for a wide range of applications in logistics and product development, Radio Frequency Identification is applied increasingly; this technology applied in conjunction with the Mobile Agent system can bring more values in managing and control the lifecycle of products by optimizing the three essential factors: cost, quality and deadline for the survival of a company in the competitive manufacturing world. In this paper we propose Mobile Agent PLM Architecture for extended enterprise, based on Mobile Agent and RFID or, more generally, Product Embedded Information Devices (PEID, for tracking and managing the information of the whole product lifecycle in the extended enterprise, and to satisfy new requirements for increased integrability, traceability, adaptability, extendibility, and closed-loop PLM. Mobile Agents are suitable for tracking information in distributing environment and the mobility aspect, at any time and any place. This paper proposes a first architecture based on these technologies.

  19. Low Cost Lithography Tool for High Brightness LED Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Andrew Hawryluk; Emily True

    2012-06-30

    The objective of this activity was to address the need for improved manufacturing tools for LEDs. Improvements include lower cost (both capital equipment cost reductions and cost-ofownership reductions), better automation and better yields. To meet the DOE objective of $1- 2/kilolumen, it will be necessary to develop these highly automated manufacturing tools. Lithography is used extensively in the fabrication of high-brightness LEDs, but the tools used to date are not scalable to high-volume manufacturing. This activity addressed the LED lithography process. During R&D and low volume manufacturing, most LED companies use contact-printers. However, several industries have shown that these printers are incompatible with high volume manufacturing and the LED industry needs to evolve to projection steppers. The need for projection lithography tools for LED manufacturing is identified in the Solid State Lighting Manufacturing Roadmap Draft, June 2009. The Roadmap states that Projection tools are needed by 2011. This work will modify a stepper, originally designed for semiconductor manufacturing, for use in LED manufacturing. This work addresses improvements to yield, material handling, automation and throughput for LED manufacturing while reducing the capital equipment cost.

  20. 75 FR 104 - Manufacturing & Services' Sustainable Manufacturing Initiative; Update

    Science.gov (United States)

    2010-01-04

    ... No: E9-31188] DEPARTMENT OF COMMERCE International Trade Administration Manufacturing & Services' Sustainable Manufacturing Initiative; Update ACTION: Notice and request for input on proposed new areas of work for the Sustainable Manufacturing Initiative which could include a series of events...

  1. Perspectives on Additive Manufacturing

    Science.gov (United States)

    Bourell, David L.

    2016-07-01

    Additive manufacturing (AM) has skyrocketed in visibility commercially and in the public sector. This article describes the development of this field from early layered manufacturing approaches of photosculpture, topography, and material deposition. Certain precursors to modern AM processes are also briefly described. The growth of the field over the last 30 years is presented. Included is the standard delineation of AM technologies into seven broad categories. The economics of AM part generation is considered, and the impacts of the economics on application sectors are described. On the basis of current trends, the future outlook will include a convergence of AM fabricators, mass-produced AM fabricators, enabling of topology optimization designs, and specialization in the AM legal arena. Long-term developments with huge impact are organ printing and volume-based printing.

  2. Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures.

    Science.gov (United States)

    Nowotarski, Shannon L; Pachaiyappan, Boobalan; Holshouser, Steven L; Kutz, Craig J; Li, Youxuan; Huang, Yi; Sharma, Shiv K; Casero, Robert A; Woster, Patrick M

    2015-04-01

    Methylation at specific histone lysine residues is a critical post-translational modification that alters chromatin architecture, and dysregulated lysine methylation/demethylation is associated with the silencing of tumor suppressor genes. The enzyme lysine-specific demethylase 1 (LSD1) complexed to specific transcription factors catalyzes the oxidative demethylation of mono- and dimethyllysine 4 of histone H3 (H3K4me and H3K4me2, respectively). We have previously reported potent (bis)urea and (bis)thiourea LSD1 inhibitors that increase cellular levels of H3K4me and H3K4me2, promote the re-expression of silenced tumor suppressor genes and suppress tumor growth in vitro. Here we report the design additional (bis)urea and (bis)thiourea LSD1 inhibitors that feature 3-5-3 or 3-6-3 carbon backbone architectures. Three of these compounds displayed single-digit IC50 values in a recombinant LSD1 assay. In addition, compound 6d exhibited an IC50 of 4.2μM against the Calu-6 human lung adenocarcinoma line, and 4.8μM against the MCF7 breast tumor cell line, in an MTS cell viability assay. Following treatment with 6b-6d, Calu-6 cells exhibited a significant increase in the mRNA expression for the silenced tumor suppressor genes SFRP2, HCAD and p16, and modest increases in GATA4 message. The compounds described in this paper represent the most potent epigenetic modulators in this series, and have potential for use as antitumor agents.

  3. Accelerating Industrial Adoption of Metal Additive Manufacturing Technology

    Science.gov (United States)

    Vartanian, Kenneth; McDonald, Tom

    2016-03-01

    While metal additive manufacturing (AM) technology has clear benefits, there are still factors preventing its adoption by industry. These factors include the high cost of metal AM systems, the difficulty for machinists to learn and operate metal AM machines, the long approval process for part qualification/certification, and the need for better process controls; however, the high AM system cost is the main barrier deterring adoption. In this paper, we will discuss an America Makes-funded program to reduce AM system cost by combining metal AM technology with conventional computerized numerical controlled (CNC) machine tools. Information will be provided on how an Optomec-led team retrofitted a legacy CNC vertical mill with laser engineered net shaping (LENS®—LENS is a registered trademark of Sandia National Labs) AM technology, dramatically lowering deployment cost. The upgraded system, dubbed LENS Hybrid Vertical Mill, enables metal additive and subtractive operations to be performed on the same machine tool and even on the same part. Information on the LENS Hybrid system architecture, learnings from initial system deployment and continuing development work will also be provided to help guide further development activities within the materials community.

  4. Towards an Architectural Anthropology

    DEFF Research Database (Denmark)

    Stender, Marie

    2016-01-01

    their overlaps and collaboration. However, there are also challenging differences to take into account regarding disciplinary traditions of, for example, communication, temporality, and normativity. This article explores the potentials and challenges of architectural anthropology as a distinct sub......Architecture and anthropology have always had overlapping interests regarding issues such as spatial organisation, forms of human dwellings, and the interplay between social life and physical surroundings. Recent developments in both disciplines make it even more relevant to explore and evolve......-discipline and outlines its possible theoretical, methodological, and applied contributions. It is proposed that the ambition to understand people in a different way than they understand themselves is key in both disciplines, and that architectural anthropology is consequently not only relevant in studies of vernacular...

  5. Persian architecture and mathematics

    CERN Document Server

    2012-01-01

    This volulme features eight original papers dedicated to the theme “Persian Architecture and Mathematics,” guest edited by Reza Sarhangi. All papers were approved through a rigorous process of blind peer review and edited by an interdisciplinary scientific editorial committee. Topics range from symmetry in ancient Persian architecture to the elaborate geometric patterns and complex three-dimensional structures of standing monuments of historical periods, from the expression of mathematical ideas to architectonic structures, and from decorative ornament to the representation of modern group theory and quasi-crystalline patterns. The articles discuss unique monuments Persia, including domed structures and two-dimensional patterns, which have received significant scholarly attention in recent years. This book is a unique contribution to studies of Persian architecture in relation to mathematics.

  6. Towards an Architectural Anthropology

    DEFF Research Database (Denmark)

    Stender, Marie

    2016-01-01

    Architecture and anthropology have always had overlapping interests regarding issues such as spatial organisation, forms of human dwellings, and the interplay between social life and physical surroundings. Recent developments in both disciplines make it even more relevant to explore and evolve...... their overlaps and collaboration. However, there are also challenging differences to take into account regarding disciplinary traditions of, for example, communication, temporality, and normativity. This article explores the potentials and challenges of architectural anthropology as a distinct sub......-discipline and outlines its possible theoretical, methodological, and applied contributions. It is proposed that the ambition to understand people in a different way than they understand themselves is key in both disciplines, and that architectural anthropology is consequently not only relevant in studies of vernacular...

  7. Agent Architectures for Compliance

    Science.gov (United States)

    Burgemeestre, Brigitte; Hulstijn, Joris; Tan, Yao-Hua

    A Normative Multi-Agent System consists of autonomous agents who must comply with social norms. Different kinds of norms make different assumptions about the cognitive architecture of the agents. For example, a principle-based norm assumes that agents can reflect upon the consequences of their actions; a rule-based formulation only assumes that agents can avoid violations. In this paper we present several cognitive agent architectures for self-monitoring and compliance. We show how different assumptions about the cognitive architecture lead to different information needs when assessing compliance. The approach is validated with a case study of horizontal monitoring, an approach to corporate tax auditing recently introduced by the Dutch Customs and Tax Authority.

  8. Ancient Chinese Landscape Architecture

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    IN the past decade,the worldhas suddenly discovered thewonders of Chinese landscapegardening and garden architecture,and places like New York,Singaporeand London have all built Chinese-style gardens.The architectural stylespecial to Chinese gardens has,infact,developed·a“school”of itsown.In China,the landscaped gardenhas long been a part of culture,andliterature,painting,philosophy,cal-ligraphy and folk customs have alldealt with it at one time or another.Two categories of garden architec-ture exist:the imperial garden andthe private garden.The former is,ofcourse,grand and palatial and occu-pies large tracts of land,while the

  9. Architecture of Environmental Engineering

    DEFF Research Database (Denmark)

    Wenzel, Henrik; Alting, Leo

    2006-01-01

    An architecture of Environmental Engineering has been developed comprising the various disciplines and tools involved. It identifies industry as the major actor and target group, and it builds on the concept of Eco-efficiency. To improve Eco-efficiency, there is a limited number of intervention......-efficiency is the aim of Environmental Engineering, the discipline of synthesis – design and creation of solutions – will form a core pillar of the architecture. Other disciplines of Environmental Engineering exist forming the necessary background and frame for the synthesis. Environmental Engineering, thus, in essence...... comprise the disciplines of: management, system description & inventory, analysis & assessment, prioritisation, synthesis, and communication, each existing at all levels of intervention. The developed architecture of Environmental Engineering, thus, consists of thirty individual disciplines, within each...

  10. Architecture of Environmental Engineering

    DEFF Research Database (Denmark)

    Wenzel, Henrik; Alting, Leo

    2004-01-01

    An architecture of Environmental Engineering has been developed comprising the various disciplines and tools involved. It identifies industry as the major actor and target group, and it builds on the concept of Eco-efficiency. To improve Eco-efficiency, there is a limited number of intervention...... of Eco-efficiency is the aim of Environmental Engineering, the discipline of synthesis – design and creation of solutions – will form a core pillar of the architecture. Other disciplines of Environmental Engineering exist forming the necessary background and frame for the synthesis. Environmental...... Engineering, thus, in essence comprise the disciplines of: management, system description & inventory, analysis & assessment, prioritisation, synthesis, and communication, each existing at all levels of intervention. The developed architecture of Environmental Engineering, thus, consists of thirty individual...

  11. Advances in Additive Manufacturing

    Science.gov (United States)

    2016-07-14

    burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching ...Society for Machinery Failure Prevention Technology conference in Dayton, OH, on 23–26 May 2016. These 6 briefs were presented in the Additive...manufacturing (AM) at the 2016 conference in Dayton, Ohio, on May 24th, 2016. The presentations included work being performed within the Department of Defense

  12. Electrohydrodynamic Printing and Manufacturing

    Science.gov (United States)

    Aksay, Ilhan A. (Inventor); Saville, Dudley A. (Inventor); Poon, Hak Fei (Inventor); Korkut, Sibel (Inventor); Chen, Chuan-hua (Inventor)

    2014-01-01

    An stable electrohydrodynamic filament is obtained by causing a straight electrohydrodynamic filament formed from a liquid to emerge from a Taylor cone, the filament having a diameter of from 10 nm to 100.mu.m. Such filaments are useful in electrohydrodynamic printing and manufacturing techniques and their application in liquid drop/particle and fiber production, colloidal deployment and assembly, and composite materials processing.

  13. Northwest Manufacturing Initiative

    Science.gov (United States)

    2012-03-27

    Training areas included Total Productive Maintenance, First Aide and Safety, Lean Training, Inventory Management, Purchasing Supply Chain, ISO 13485 ...improve their business through quality certifications and initiatives such as AS9100, ISO 9001-2000, and implementing Lean Manufacturing. All of these...not show up on a visible profile. 13 Certifications: Quality Certifications such as AS9100, ISO etc. a. List Certifying Agency and number

  14. Manufacturing of Lightweight Mirror

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Fabrication of the lightweight mirror is one of the key techniques for many large optical systems. CAD,CAM and CNC technologies are adopted in designing and manufacturing such mirrors in CIOMP. Better working efficiency and higher lightweight grade have been achieved. The results show that mirrors up to 70% weight reduction and 0.02λ(rms.) surface accuracy or better can be obtained.

  15. Effects of tributylborane-activated adhesive and two silane agents on bonding computer-aided design and manufacturing (CAD/CAM) resin composite.

    Science.gov (United States)

    Shinohara, Ayano; Taira, Yohsuke; Sawase, Takashi

    2017-01-09

    The present study was conducted to evaluate the effects of an experimental adhesive agent [methyl methacrylate-tributylborane liquid (MT)] and two adhesive agents containing silane on the bonding between a resin composite block of a computer-aided design and manufacturing (CAD/CAM) system and a light-curing resin composite veneering material. The surfaces of CAD/CAM resin composite specimens were ground with silicon-carbide paper, treated with phosphoric acid, and then primed with either one of the two silane agents [Scotchbond Universal Adhesive (SC) and GC Ceramic Primer II (GC)], no adhesive control (Cont), or one of three combinations (MT/SC, MT/GC, and MT/Cont). A light-curing resin composite was veneered on the primed CAD/CAM resin composite surface. The veneered specimens were subjected to thermocycling between 4 and 60 °C for 10,000 cycles, and the shear bond strengths were determined. All data were analyzed using analysis of variance and a post hoc Tukey-Kramer HSD test (α = 0.05, n = 8). MT/SC (38.7 MPa) exhibited the highest mean bond strengths, followed by MT/GC (30.4 MPa), SC (27.9 MPa), and MT/Cont (25.7 MPa), while Cont (12.9 MPa) and GC (12.3 MPa) resulted in the lowest bond strengths. The use of MT in conjunction with a silane agent significantly improved the bond strength. Surface treatment with appropriate adhesive agents was confirmed as a prerequisite for veneering CAD/CAM resin composite restorations.

  16. Advanced manufacturing: Technology diffusion

    Energy Technology Data Exchange (ETDEWEB)

    Tesar, A.

    1995-12-01

    In this paper we examine how manufacturing technology diffuses rom the developers of technology across national borders to those who do not have the capability or resources to develop advanced technology on their own. None of the wide variety of technology diffusion mechanisms discussed in this paper are new, yet the opportunities to apply these mechanisms are growing. A dramatic increase in technology diffusion occurred over the last decade. The two major trends which probably drive this increase are a worldwide inclination towards ``freer`` markets and diminishing isolation. Technology is most rapidly diffusing from the US In fact, the US is supplying technology for the rest of the world. The value of the technology supplied by the US more than doubled from 1985 to 1992 (see the Introduction for details). History shows us that technology diffusion is inevitable. It is the rates at which technologies diffuse to other countries which can vary considerably. Manufacturers in these countries are increasingly able to absorb technology. Their manufacturing efficiency is expected to progress as technology becomes increasingly available and utilized.

  17. Information architecture. Volume 3: Guidance

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    The purpose of this document, as presented in Volume 1, The Foundations, is to assist the Department of Energy (DOE) in developing and promulgating information architecture guidance. This guidance is aimed at increasing the development of information architecture as a Departmentwide management best practice. This document describes departmental information architecture principles and minimum design characteristics for systems and infrastructures within the DOE Information Architecture Conceptual Model, and establishes a Departmentwide standards-based architecture program. The publication of this document fulfills the commitment to address guiding principles, promote standard architectural practices, and provide technical guidance. This document guides the transition from the baseline or defacto Departmental architecture through approved information management program plans and budgets to the future vision architecture. This document also represents another major step toward establishing a well-organized, logical foundation for the DOE information architecture.

  18. Manufacturing a Superconductor in School.

    Science.gov (United States)

    Barrow, John

    1989-01-01

    Described is the manufacture of a superconductor from a commercially available kit using equipment usually available in schools or easily obtainable. The construction is described in detail including equipment, materials, safety procedures, tolerances, and manufacture. (Author/CW)

  19. 78 FR 67117 - Manufacturing Council

    Science.gov (United States)

    2013-11-08

    ... International Trade Administration Manufacturing Council AGENCY: International Trade Administration, U.S... States remains the preeminent destination for investment in manufacturing throughout the world'' as... participating in Council meetings and events are responsible for their travel, living and other...

  20. Green Manufacturing Fundamentals and Applications

    CERN Document Server

    2013-01-01

    Green Manufacturing: Fundamentals and Applications introduces the basic definitions and issues surrounding green manufacturing at the process, machine and system (including supply chain) levels. It also shows, by way of several examples from different industry sectors, the potential for substantial improvement and the paths to achieve the improvement. Additionally, this book discusses regulatory and government motivations for green manufacturing and outlines the path for making manufacturing more green as well as making production more sustainable. This book also: • Discusses new engineering approaches for manufacturing and provides a path from traditional manufacturing to green manufacturing • Addresses regulatory and economic issues surrounding green manufacturing • Details new supply chains that need to be in place before going green • Includes state-of-the-art case studies in the areas of automotive, semiconductor and medical areas as well as in the supply chain and packaging areas Green Manufactu...