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Sample records for actinomycosis

  1. Actinomycosis

    Science.gov (United States)

    Treatment of actinomycosis usually requires antibiotics for several months to a year. Surgical drainage or removal of the affected area (lesion) may be needed. If the condition is related to an IUD, the device must be removed.

  2. Pelvic actinomycosis.

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    Gorisek, B; Rebersek-Gorisek, H; Kavalar, R; Krajnc, I; Zavrsnik, S

    1999-08-20

    Pelvic actinomycosis is a rare chronic infection caused by bacteria of the family Actinomycetaceae. Prolonged use of an intrauterine contraceptive device (IUD) is a well known risk factor. We report six patients with pelvic actinomycosis, all of whom had an IUD inserted for over six years. Diagnostic problems necessitated a laparotomy in all patients. The pathohistological diagnosis was based on the characteristic microscopic image and specific staining. The patients were treated with penicillin and amoxycillin for several months.

  3. Abdominal actinomycosis.

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    Wagenlehner, F M E; Mohren, B; Naber, K G; Männl, H F K

    2003-08-01

    Intra-abdominal and extraperitoneal actinomycosis are rare infections, caused by different Actinomyces species. However, they have been diagnosed more frequently in the last ten years. We report three cases of abdominal actinomycosis and a literature review of the last eight years. All three patients were diagnosed by means of histopathologic examination only. In one case, an intrauterine device (IUD) was associated with the infection. Therapy consisted of surgical resection of the inflammatory, infected tissue, and long-term antibiotic therapy. All patients are free of recurrence. Abdominal actinomycosis should be included in the differential diagnosis of an abdominal pathology of insidious onset, especially when an IUD is in place. Even when infection had spread extensively, combined operative and antibiotic therapy cured most of the cases.

  4. Spinal actinomycosis: A rare disease

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    Dua Rakesh

    2010-01-01

    Full Text Available Actinomycosis is an indolent, slowly progressive infection caused by Actinomyces species. Of human actinomycosis, the spinal form is rare and actinomycosis-related spinal neurological deficit is uncommon. We report two cases with cervical and dorsal actinomycosis and one of them with spinal neurological deficit.

  5. Case report: pelvic actinomycosis.

    Science.gov (United States)

    Maxová, K; Menzlová, E; Kolařík, D; Dundr, P; Halaška, M

    2012-01-01

    A case of pelvic actinomycosis is presented. The patient is 42-year-old female with a 5 weeks history of pelvic pain. An intrauterine device (IUD) was taken out 3 weeks ago. There is a lump length 9 cm between rectus muscles. Ultrasound, magnetic resonance imaging (MRI) and histology are used to make the diagnosis. Actinomycosis can mimic the tumour disease. The definitive diagnosis requires positive anaerobic culture or histological identification of actinomyces granulas. A long lasting antibiotic therapy is performed.

  6. [Thoracic actinomycosis: three cases].

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    Herrak, L; Msougar, Y; Ouadnouni, Y; Bouchikh, M; Benosmane, A

    2007-09-01

    Actinomycosis is a rare condition which, in the thoracic localisation, can mimic cancer or tuberculosis. We report a series of three case of thoracic actinomycosis treated in the Ibn Sina University Thoracic Surgery Unit in Rabat, Morocco. CASE N degrees 1: This 45-year-old patient presented a tumefaction on the left anterior aspect of the chest. Physical examination identified a parietal mass with fistulisation to the skin. Radiography demonstrated a left pulmonary mass. Transparietal puncture led to the pathological diagnosis of actinomycosis. The patient was given medical treatment and improved clinically and radiographically. CASE N degrees 2: This 68-year-old patient presented repeated episodes of hemoptysis. The chest x-ray revealed atelectasia of the middle lobe and bronchial fibroscopy demonstrated the presence of a bud in the middle lobar bronchus. Biopsies were negative. The patient underwent surgery and the histology examination of the operative specimen revealed pulmonary actinomycosis. The patient recovered well clinically and radiographically with antibiotic therapy. CASE N degrees 3: This 56-year-old patient presented cough and hemoptysis. Physical examination revealed a left condensation and destruction of the left lung was noted on the chest x-ray. Left pleuropulmonectomy was performed. Histological analysis of the surgical specimen identified associated Aspergillus and Actinomyces. The outcome was favorable with medical treatment. The purpose of this work was to recall the radiological, clinical, histological, therapeutic, outcome aspects of this condition and to relate the problems of differential diagnosis when can suggest other diseases.

  7. A Case of Ovarian Actinomycosis

    OpenAIRE

    2003-01-01

    Background: Pelvic actinomycosis is uncommon and often presents as a complication of an intrauterine device (IUD). A diagnosis of actinomycosis can be made from the finding of sulfur granules within inflammatory exudate on histologic examination after surgery. However, it may be possible to diagnose actinomycosis before surgery by finding Actinomyces-like organisms on Papanicolaou smears. Case: A 41-year-old woman had been diagnosed as having a pelvic abscess, and bilateral salpingo-oophorect...

  8. Pelvic actinomycosis: urologic perspective

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    Venkata K. Marella

    2004-10-01

    Full Text Available PURPOSE: Actinomycosis is a chronic granulomatous infection caused by the gram-positive anaerobic bacteria, Actinomyces israelli. This paper reviews the etiology and clinical presentation associated with Actinomycosis that often presents as a pelvic mass that mimics a pelvic malignancy. MATERIALS AND METHODS: A combination of patients treated by the authors in the recent past and a literature review of patients with pelvic Actinomycosis were assessed for diographic, clinical and predisposing co-factors. An analysis is made of age distribution, gender, diagnostic methods and treatment concepts. RESULTS: Thirty-three patients were included in the study that included 2 current patients and 31 obtained from literature review. There were 27 fiales (age range 16 - 69 years, mean 38 years and 6 males (16 - 55 years, mean 36 years. Presenting signs and symptoms were lower abdominal mass in 28 (85%; lower abdominal pain in 21 (63%; vaginal discharge or hiaturia in 7 (22%. Two patients developed fistulae (entero-vesico 1; vesico-cutaneous 1. Nineteen (70% of the 27 fiale patients had intra-uterine contraceptive devices (IUD. Four patients (12.5% (3 males and 1 fiale had urachus or urachal rinants. Cystoscopy in 12 patients noted an extrinsic mass effect, bullous edia and in one patient vegetative proliferation proven to be a chronic inflammatory change. Exploratory laparotomy was performed in 32 of the 33 patients who had excision of mass and involved organs. Diagnosis was established by histologic examination of rioved tissue. Penicillin (6 weeks therapy was utilized to control infections. CONCLUSION: Pelvic actinomycosis mimics pelvic malignancy and may be associated with the long-term use of intra-uterine contraceptive devices, and persistent urachal rinants. Rioval of infected mass and antibiotic therapy will eradicate the inflammatory process.

  9. [Abdominal actinomycosis with IUD].

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    Kamprath, S; Merker, A; Kühne-Heid, R; Schneider, A

    1997-01-01

    We report a case of abdominal actinomycosis in a 54 year old woman using an intrauterine device for a period of 8 years. The most important finding was a tuboovarialabscess at the left pelvic side with involvement of the serosa of the jejunum, ileum, sigma, and omentum majus. Intraoperative exploration showed a solid retroperitoneal infiltration between the pelvic side wall and sigma. Another infiltration was found on the left side of the abdominal wall. The diagnosis was confirmed by histopathological examination and the patient was treated by a combination of Aminopenicillin and Metronidazol. After a period of three months we observed a complete regression of the clinical and the MRI findings.

  10. A Case of Ovarian Actinomycosis

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    Nishikawa, Akira; Akutagawa, Noriyuki; Fujimoto, Takashi; Teramoto, Mizue; Kudo, Ryuichi

    2003-01-01

    Background: Pelvic actinomycosis is uncommon and often presents as a complication of an intrauterine device (IUD). A diagnosis of actinomycosis can be made from the finding of sulfur granules within inflammatory exudate on histologic examination after surgery. However, it may be possible to diagnose actinomycosis before surgery by finding Actinomyces-like organisms on Papanicolaou smears. Case: A 41-year-old woman had been diagnosed as having a pelvic abscess, and bilateral salpingo-oophorectomy was performed. She had been an IUD user for 6 years. Actinomyces-like organisms were detected in her previous Papanicolaou cervical smears. If the patient had been treated when the Actinomyces-like organisms were detected by Papanicolaou smears, the serious ovarian actinomycosis might have been avoided. Conclusion: We suggest that routine cervical examinations are important for women who are IUD users. PMID:15022879

  11. Actinomycosis - Left Post Chest Wall

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    Kafil Akhtar, M. Naim, S. Shamshad Ahmad, Nazoora Khan, Uroos Abedi, A.H. Khan*

    2008-01-01

    Full Text Available A forty year old female of weak body built presented with recurring small hard lumps in let posteriorchest wall for 3 years and discharging ulcers for 3 months duration. Clinically, the provisional diagnosiswas malignancy with secondary infection. FNAC showed features suggestive of dysplasia buthistopathology confirmed the diagnosis as actinomycosis. The present case is reported due to rare incidenceof actinomycosis at post chest wall with muscle involvement.

  12. Cutaneous actinomycosis: A rare case

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    Metgud S

    2007-01-01

    Full Text Available Cutaneous actinomycosis is a rare presentation. Here we present a case of cutaneous actinomycosis with no history of trauma or systemic dissemination. The isolate was identified as Actinomyces viscosus by standard methods. The isolate was found to be penicillin resistant by Kirby Bauer disc diffusion method. Therefore, the patient was treated with cotrimoxazole and improved. Thus, this case highlights the importance of isolation and susceptibility testing in actinomycotic infection. The sinuses have healed, and the patient has recovered.

  13. Abdominal actinomycosis mimicking acute appendicitis.

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    Conrad, Robert Joseph; Riela, Steven; Patel, Ravi; Misra, Subhasis

    2015-01-01

    A 52-year-old Hispanic woman presented to the emergency department, reporting worsening sharp lower right quadrant abdominal pain for 3 days. CT of the abdomen and pelvis showed evidence of inflammation in the peritoneal soft tissues adjacent to an enlarged and thick-walled appendix, an appendicolith, no abscess formation and a slightly thickened caecum consistent with acute appendicitis. During laparoscopic appendectomy, the caecum was noted to be firm, raising suspicion of malignancy. Surgical oncology team was consulted and open laparotomy with right hemicolectomy was performed. Pathology reported that the ileocaecal mass was not a malignancy but was, rather, actinomycosis. The patient was discharged after 10 days of intravenous antibiotics in the hospital, with the diagnosis of abdominal actinomycosis. Although the original clinical and radiological findings in this case were highly suggestive of acute appendicitis, abdominal actinomycosis should be in the differential for right lower quadrant pain as it may be treated non-operatively.

  14. [IUD-associated abdominopelvic actinomycosis].

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    Anteby, E; Milvidsky, A; Goshen, R; Ben-Chetrit, A; Ron, M

    1991-09-01

    Abdominopelvic actinomycosis associated with the use of an intrauterine contraceptive device (IUD) is described. The diagnosis is usually made after exploratory laparotomy for severe abdominal pain and signs of an acute abdomen, or for prolonged lower abdominal pain and findings consistent with pelvic malignancy. 3 women aged 33, 44 and 52 years, respectively, are presented.

  15. Actinomycosis of The Tongue: A Diagnostic Dilemma

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    Aniece Chowdary, Anirudh Kaul, Surinder Atri*

    2010-10-01

    Full Text Available Actinomycosis is a bacterial, suppurative chronic infectious disease caused by Actinomyces israelli.Actinomycotic infections of the cervicofacial region are not uncommon , however Actinomycosis of tongueis rare. A mass that may mimic both benign and malignant neoplasms can be seen at clinical presentationand may mislead the diagnosis. We report a patient who presented with a tumor like tongue mass causingspeech disturbance and difficulty in swallowing, diagnosed as actinomycosis

  16. [Genital actinomycosis in women wearing IUD].

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    Brittig, F; Bánlaki, S

    1980-12-14

    The authors describe genital actinomycosis in 5 women using the IUD. They call attention to the relationship between the IUD and actinomycosis. They think it necessary to examine tissues and fluids adhering to the IUD coil upon removal. And they recommend that this be supplemented by regular cytological examination of the coil, with this data being associated with data from screening.

  17. [Actinomycosis and the intrauterine spiral].

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    Puchner, T; Egarter, C

    1995-05-01

    Genital actinomycosis infections are relatively rare and show a strong coincidence with long-lasting IUD application. Two patients without symptoms, where diagnosis was made by means of Papanicolaou smears were compared with two patients, where removal of a tubo-ovarian mass led to diagnosis. A general agreement about diagnosis and especially screening tests is still missing, but there seems to be a consensus regarding the types of IUD, the duration of use, and the sexual behaviour of the couple.

  18. Actinomycosis of urinary bladder - a rare entity

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    Chaman Lal Gupta

    2003-01-01

    Full Text Available Actinomycosis is considered the most misdiagnosed dis-ease usually involving the cervico fascial region, thorax, abdomen and occasionally also the pelvis, usually in case of the females using intra-uterine devices. The involve-ment of the urinary tract is rare and primary actinomyco-sis of urinary bladder is still rarer. The disease is usually diagnosed by demonstration of the discharged sulphur granules. In our case this was not the usual presentation and the patient was first diagnosed as having appendicu-lar mass and then bladder malignancy. The excised mass demonstrated features suggestive of actinomycosis.

  19. Renal actinomycosis with concomitant renal vein thrombosis.

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    Chang, Dong-Suk; Jang, Won Ik; Jung, Ji Yoon; Chung, Sarah; Choi, Dae Eun; Na, Ki-Ryang; Lee, Kang Wook; Shin, Yong-Tai

    2012-02-01

    Renal actinomycosis is a rare infection caused by fungi of the genus Actinomyces. A 74-year-old male was admitted to our hospital because of gross hematuria with urinary symptoms and intermittent chills. Computed tomography of the abdomen showed thrombosis in the left renal vein and diffuse, heterogeneous enlargement of the left kidney. After nephrectomy, sulfur granules with chronic suppurative inflammation were seen microscopically, and the histopathological diagnosis was renal actinomycosis. Our case is the first report of renal actinomycosis with renal vein thrombosis.

  20. Diagnosis and therapy of pelvic actinomycosis.

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    Taga, Shigeki

    2007-12-01

    Pelvic actinomycosis is difficult to diagnose. In most cases, it is not diagnosed until after surgery. If this condition is diagnosed preoperatively, it can be treated in many cases. Three cases of actinomycosis are reported here. Three women with intrauterine devices (IUD) each presented with lower abdominal pain and pelvic mass, and elevated white blood cell count and C-reactive protein. Left salpingo-oophorectomy was performed for one the women. The pathological diagnosis was actinomycosis. For the other two women, a Gram or Papanicolaou stain of the IUD sample showed actinomycetes. They were discharged after intravenous administration of penicillin without surgery.

  1. Cutaneous actinomycosis. A case report

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    Tomasz Wasyłyszyn

    2016-10-01

    Full Text Available A 27 year old patient presented a swollen lesion in the right mandibular area. Prior to the visit the patient was diagnosed with acne and was treated for 6 consecutive months with oral limecycline with no positive response. During the visit the cervicofacial actinomycosis was diagnosed and the patient was administered treatment containing oral amoxycilin plus clavulanic acid among others. The skin lesion disappeared within three weeks. The authors discuss this case in spite of diagnostic difficulties of this uncommon condition, especially while differentiating from acne conglobata.

  2. Vocal Cord Actinomycosis: A Case Report

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    Bijan Khademi

    2011-04-01

    Full Text Available Introduction: Actinomycosis is a systemic chronic bacterial infection caused by Actinomyces Israelii, an anaerobic organism normally resident in the human mouth. However, the actinomycosis of the larynx is very rare, and only about 15 cases have been reported in the literature so far. Most of the cases reported occurred in patients who had previously undergone radiotherapy for laryngeal cancer. Case Report: Here we report a case of actinomycosis of the larynx in a 14-year-old shepherd boy who was not immunocompromised but had a history of tooth extraction two months prior to admission to the hospital and severe laryngitis one year prior to admission. Conclusion:        Laryngeal actinomycosis might be related to poor oral hygiene and mucosal barrier disruption, as well as to being immunocompromised.

  3. Misleading diagnosis of retroperitoneal actinomycosis

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    Berchtenbreiter, C.; Bruening, R.; Reiser, M. [Inst. of Diagnostic Radiology, University Hospital Grosshadern, Ludwig Maximilians University, Munich (Germany); Auernhammer, A. [Medical Clinic II, Univ. Hospital Grosshadern, Ludwig Maximilians University, Munich (Germany)

    1999-07-01

    A 34-year-old woman presented with a left-sided suprarenal space-occupying lesion on sonography. Culture of material obtained during sonographic-guided puncture of the retroperitoneal lesion yielded a mixed flora of Actinomyces and Peptostreptococcus. Initially, a misleading diagnosis of an adrenal pheochromocytoma was initiated by highly positive metaiodobenzylguanidine scintigraphy after chemical chemistry vanillylmandelic acid (VMA) test showed elevated values for adrenaline and its derivatives. Retroperitoneal actinomycosis with yet unproven spread into thoracic and cervical compartments is a particular unusual presentation of an infection with these organisms. Because it may mimic subacute infections or malignant masses in terms of clinical and laboratory findings, radiological diagnosis of this entity may be difficult. The diagnosis was based on results of culture and the response of the patient to long-term penicillin-derivate therapy after surgical drainage of the suprarenal abscess formation. (orig.)

  4. [Pelvic actinomycosis in Tunisia: five cases].

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    Chelli, Dalenda; Hassini, Abdelwahed; Aloui, Fadhel; Sfar, Ezzeddine; Zouaoui, Béchir; Chelli, Héla; Chanoufi, Badis

    2008-01-01

    Actinomycosis is a rare suppurative disease due to Actinomyces species. These Gram-positive, non-acid fast anaerobic filamentous bacteria are normal inhabitants of the human body, tending to reside in the oropharynx and bowel but are occasionally found in the vagina. Pelvic actinomycosis is a rare bacterial disease in women. Clinical manifestations are various and non specific and may be acute or chronic. No consensus exists for treatment. We reviewed files and identified all five cases of pelvic actinomycosis managed at Obstetrics and Gynaecology department "A" at the Maternity Center of Tunis over an eight-year period (1998-2005). The women's average age was 39.2 years. One patient was menopausal and consulted for bleeding. The other four patients were younger and had all been using an intrauterine device (IUD) for contraception. They presented with acute clinical manifestations. Their main symptom was pelvic pain. Three women had fever, and two presented with urinary tract obstruction. All patients had surgery. A pelvic abscess was found in four cases. Laparoscopic management was possible in only one case. Laparotomy was necessary in the other four. Four women had adnexectomies, two with hysterectomy. Digestive complications occurred in three cases. Actinomycosis was diagnosed only after surgery, by the histological examination. This series confirms the difficulties encountered in the management of pelvic actinomycosis. We review the recent literature and describe the diagnostic and therapeutic procedures currently recommended. The relationship between pelvic actinomycosis and IUDs, the most common method of contraception in Tunisia, is clearly established. Clinical diagnosis of pelvic actinomycosis is difficult because the symptoms are non-specific. Laboratory tests can help by showing serious inflammation, however. Imaging findings are also non-specific and may suggest an abscess or an inflammatory or neoplastic process. Interventional radiology, specifically

  5. [Pelvic actinomycosis and sub-acute abdomen].

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    Messalli, E M; Cobellis, L; Festa, B; Pecori, E; Stradella, L; Cobellis, G

    2002-12-01

    An interesting case of pelvic actinomycosis with paculiar clinical manifestation is presented. A 42 years-old patient came to our emergency service for an abdominal pelvic pain and fever. Past history showed IUD in situ for over 15 years. The patient was submitted to a ultrasonographic scan and a complete hematological screening was performed. The diagnosis was of subacute abdomen, and an exploratory laparotomy was carried out. During laparotomy an atypical reactive tissue and a suppurative cavity were found. The histological finding of tissue biopsy showed pelvic actinomycosis. On the basis of these findings the conclusion is drawn that a better prevention of pelvic actinomycosis is necessary of its diffusion in the last years due to sexual habit changes.

  6. Uncommon presentation of actinomycosis mimicking colonic cancer: Colon actinomycosis with invasion of the abdominal wall

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    Ilhan Bali

    2015-04-01

    Full Text Available Actinomycosis is an uncommon chronic suppurative infectious disease that is caused by Actinomycetes organisms, which are gram-positive, microaerophilic, anaerobic bacteria. Herein, we present the case of a 42-year-old female patient who underwent surgical exploration following presentation with abdominal pain and an abdominal mass, initially thought to be a malignancy. Histological examination of the specimen revealed colon actinomycosis. [Arch Clin Exp Surg 2015; 4(2.000: 107-110

  7. Actinomycosis mimicking abdominal neoplasm. Case report

    DEFF Research Database (Denmark)

    Waaddegaard, P; Dziegiel, Morten Hanefeld

    1988-01-01

    In a patient with a 6-month history of nonspecific abdominal complaints, preoperative examination indicated malignant disease involving the right ovary, rectum and sigmoid, but laparotomy revealed abdominal actinomycosis. Removal of the ovary and low anterior colonic resection followed by penicil...

  8. Abdominal manifestations of actinomycosis in IUD users.

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    Asuncion, C M; Cinti, D C; Hawkins, H B

    1984-08-01

    The use of an intrauterine device (IUD) is associated with the presence of actinomyces in the female genital tract. Since IUD use is currently so prevalent, IUD-related pelvic inflammatory disease occasionally spreads to the rest of the abdomen. Two patients with abdominal actinomycosis in association with an IUD illustrate the problem; we review the general problem.

  9. Pelvic actinomycosis associated with intrauterine device use: case report

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    Alfuhaid, T. [Dept. of Medical Imaging, Univ. Health Centre and Mount Sinai Hospital, Toronto General Hospital, Toronto, Ontario (Canada); Reinhold, C. [Radiology, Gastroenterology and Gynecology, McGill Univ. Health Centre, Montreal General Hospital, Montreal, Quebec (Canada)

    2003-06-01

    Pelvic actinomycosis is a rare disease that may complicate longstanding intrauterine device (IUD) use. Its timely recognition is crucial to minimize morbidity and avoid the erroneous diagnosis of malignancy with subsequent, unnecessary surgery. We describe a case of pelvic actinomycosis. The role of magnetic resonance imaging (MRI) in recognizing this infectious disease process is stressed. (author)

  10. A case of pelvic actinomycosis presenting as cutaneous fistula.

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    Tedeschi, Amando; Di Mezza, Giovanni; D'Amico, Odette; Ermann, Alfredo; Montone, Luigi; Siciliano, Marcello; Cobellis, Giovanni

    2003-05-01

    Actinomycosis of the female genital tract has greatly increased over the last two decades. A pelvic form of the disease, associated with the use of Intra-uterine Devices (IUD), can severely damage pelvic organs and even can lead to death. We report a case of pelvic actinomycosis presenting as cutaneous fistula.

  11. Actinomycosis of the female genital tract.

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    Lomax, C W; Harbert, G M; Thornton, W N

    1976-09-01

    Four cases of actinomycosis involving the uterus and adnexal structures are reported. In 2 cases the infection was transmitted from a ruptured appendix. Ascending actinomycosis involving the endometrium and resulting in adnexal abscesses was associated with the use of an IUD in 2 patients. This infection should be suspected in any patient who develops a pelvic abscess with an IUD in place. Culture and histologic examination of tissue removed with the IUD may be a means of early diagnosis. The nature of these infections became apparent only after serious complications developed. Each patient required several surgical procedures. The diagnosis remained unsuspected until repeated laboratory examinations detected the fungus. The difficulty encountered identifying Actinomyces israeli indicates the infection is often undetected. Gallium scans were helpful in localizing occult abscesses in 2 patients.

  12. [Pelvic actinomycosis in menopausal patient, case review].

    Science.gov (United States)

    Treviño Salinas, Emilio Modesto; Martínez Palones, José María; Pérez Benavente, Ma Asunción; Xercavins Montosa, Jordi

    2003-10-01

    Pelvic actinomycosis is a granulomatous chronic illness due to anaerobic, gram-positive, branching filamentous bacteria (Actinomyces israelii), this and other species of actinomyces occur in the normal flora of the gastrointestinal and genital tract in humans. Infection is associated in women using an IUD (Intrauterine device) for long periods and it has the characteristic of simulate malignant diseases causing most of the times wrong preoperative diagnosis. We analyzed a postmenopausal patient who was treated surgically without specific diagnosis, then by anatomo-pathologic study of the specimen the result was actinomycosis. The main purpose to obtain the correct preoperative diagnosis is because we have to use antibiotics in the treatment and it may reduce the frequency of radical surgeries.

  13. Tubo-ovarian Actinomycosis Mimicking Ovarian Malignancy: Case Report

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    Faten Limaiem

    2015-09-01

    Full Text Available Actinomycosis is a chronic suppurative granulomatous infection caused by Actinomyces israelii, an anaerobic Gram-positive microorganism. Pelvic actinomycosis is rare and constitutes 3% of all human actinomycosis infections. Pre-operative diagnosis is usually difficult with the majority of cases being diagnosed after the histological and bacteriological examination of the resected specimen. In this paper, the authors report a new case of tubo-ovarian actinomycosis in a 42-year-old woman that was misdiagnosed pre-operatively as ovarian malignancy. Tubo-ovarian actinomycosis should be considered in patients with a pelvic mass especially in ones using intra-uterine devices. Surgeons should be aware of this infection in order to avoid excessive surgical procedures. [J Interdiscipl Histopathol 2015; 3(3.000: 117-119

  14. [Inflammation of the small pelvis caused by Actinomycosis infection].

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    Koltai, M; Barkai, L; Hardonyi, A

    1991-02-03

    Authors report their observations obtained in the course of treatment of 36 patients suffered from pelvic Actinomycosis. The course of disease of patients treated with pelvic inflammatory disease during a period of five years was compared with the occurrence at IUD users and non-users. The interdependence of occurrence of Actinomycosis, as well as previous deliveries, abortions and the period of use of IUD was investigated retrospectively. Difference was made between primary and secondary Actinomycosis. Authors investigated the methods of diagnostics of Actinomycosis and those of prevention and treatment. It was stated that because of pelvic Actinomycosis at IUD users the surgical intervention was not higher than the PID caused by other pathogenic. microorganisms.

  15. [Actinomycosis of the pelvis with an indwelling IUD].

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    Kurz, R; Amon, K; Laqua, D; Fischbach, F; Buck, J; Heinkelein, J

    2000-05-01

    Infection with actinomycosis israeli (an anaerobic, gram-positive bacterium) presents as chronic inflammation with tendency to fibrosis and suppuration with formation of external sinuses. Cervicofacial, thoracic and abdominal forms of the disease made up 95% of cases of actinomycosis. A 53-year-old woman was admitted to the hospital because of a pelvic mass which was thought to be malignant. A laparotomy was performed and the histologic examination showed actinomycosis. The patient first received penicillin followed by tetracyclin and the pelvic mass shrunk. One year later no more mass was detectable. We think that the IUP in place over years is the source for this infection.

  16. [Genital actinomycosis. Diagnostic and therapeutic difficulties. Report of three cases].

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    Atallah, D; Lizee, D S; Van den Akker, M; Gadonneix, P; Tranbaloc, P; Villet, R

    1999-01-01

    Genital actinomycosis is a rare bacterial infection affecting women of child-bearing age, which is sometimes related to the use of an IUD or an intra-vaginal pessary. Nevertheless, this relationship is at best tenous and actinomycosis is not the only bacterial infection caused by IUD use. Genital actinomycosis often occurs as a pelvic tumour which is sometimes difficult to correctly diagnose and consequently treat accordingly. Rapid diagnosis is essential in order to avoid any irreparable tissue damage. Treatment of this condition consists of a combination of antibiotics and surgery to achieve complete recovery. Three cases are described.

  17. Actinomycosis--an unusual case of an uncommon disease.

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    Petrone, L R; Sivalingam, J J; Vaccaro, A R

    1999-01-01

    Actinomycosis is an uncommon disease caused by organisms of the Actinomyces genus. These organisms are commonly found in the mucous membranes but do not cause infection unless there is disruption of the membranes, as occurs, for example, during dental trauma or abdominal surgery. Use of an IUD is also a risk factor for pelvic actinomycosis. The disease is usually insidious and is often mistaken for other conditions. Treatment of the infection, once diagnosed, is a regimen of long-term antibiotics such as penicillin, clindamycin, and others. Our patient had pelvic and sacral actinomycosis without any of the traditional risk factors for infection.

  18. Incidence of actinomycosis associated with intrauterine devices.

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    Chatwani, A; Amin-Hanjani, S

    1994-08-01

    The incidence of intrauterine device (IUD)-associated cervicovaginal actinomycosis was evaluated. Papanicolaou-stained cervicovaginal smears from 1,520 women with IUDs were reviewed for the presence of Actinomyces-like organisms. The overall colonization rate was 11.4%. The colonization rates for the Progestasert, plastic IUDs and copper IUDs were 14.3%, 10.8% and 6.69%, respectively. The colonization rate appeared to increase with the duration of IUD use. The relatively high cervicovaginal Actinomyces colonization rate suggests that all patients with IUDs should undergo annual cytologic smears, with specific attention given to the presence of Actinomyces-like organisms.

  19. [Primary hepatic actinomycosis: a case of inflammatory pseudotumor (case report)].

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    Tamsel, Sadik; Demirpolat, Gülgün; Killi, Refik; Elmas, Nevra

    2004-06-01

    Actinomycosis is an uncommon chronic infection in which primary liver involvement accounts for 5% of all actinomycotic infections. Abdominal actinomycosis is a severe and progressive peritoneal infection due to an anaerobic gram-positive bacterium, Actinomyces israelii. The presence of a long-standing intrauterine device (IUD) is a well-known risk factor in young women. Although hepatic lesions are present in 15% of cases of abdominal actinomycotic infection, liver involvement in the majority of these cases is attributable to metastatic spread from other evident intraabdominal sites. Hepatic actinomycosis presents most commonly as a single abscess. However, hepatic actinomycosis can closely mimic a malignant tumor on clinical and radiological examination. Such lesions have been termed inflammatory pseudotumors. Tissue specimens for microscopic examination are necessary for diagnosis. We report a rare case of inflammatory pseudotumor of the liver caused by actinomycotic infection.

  20. Genital tract actinomycosis caused by Actimyces israëlii.

    Science.gov (United States)

    Quercia, R; Bani Sadr, F; Cortez, A; Arlet, G; Pialoux, G

    2006-07-01

    We report a case of actinomycosis caused by actinomyces israelii, related to the removal of intrauterine device (IUD). Diagnosing actinomycosis is difficult but should be considered in the event of any acute abdominal problems in a woman carrying an IUD. All abdominal organs may be affected. Even with a disseminated infection, the combination of appropriate antibiotic therapy (penicillin G) and surgery ensures a full recovery in most cases.

  1. Abdominal wall actinomycosis associated with an IUD. A case report.

    Science.gov (United States)

    Adachi, A; Kleiner, G J; Bezahler, G H; Greston, W M; Friedland, G H

    1985-02-01

    Abdominal wall actinomycosis without pelvic organ involvement in users of intrauterine contraceptive devices (IUDs) has not been reported on previously. We encountered one such patient, whose uterine cervix was colonized superficially with Actinomyces. We suggest that systemic actinomycosis be included in the differential diagnosis of pain in IUD users when Actinomyces is found on Papanicolaou smears or in endocervical curettings. Such patients should be treated with appropriate antibiotic therapy, especially prior to any surgical intervention.

  2. Abdominal-Pelvic Actinomycosis Mimicking Malignant Neoplasm

    Directory of Open Access Journals (Sweden)

    Teresa Pusiol

    2011-01-01

    Full Text Available Abdominal-pelvic actinomycosis is often mistaken for other conditions, presenting a preoperative diagnostic challenge. In a 46-year-old female, computed tomography showed an abdominal-pelvic retroperitoneal mass extending from the lower pole of the right kidney to the lower pelvis. The patient had a 3-year history of intrauterine device. The mass appeared to involve the ascending colon, cecum, distal ileum, right Fallopian tube and ovary, and ureter anteriorly and the psoas muscle posteriorly. The resection of retroperitoneal mass, distal ileum appendicectomy, right hemicolectomy, and right salpingo-oophorectomy was performed. The postoperative period was uneventful. Penicillin therapy was given for six months without any complication. The retroperitoneal mass measured 4.5 × 3.5 × 3 cm, surrounded adjacent organs and histologically showed inflammatory granulomatous tissue, agglomeration of filaments, and sulfur granules of Actinomyces, with positive reaction with periodic acid Schiff. Right tubo-ovarian abscess was present. Abdominalpelvic actinomycosis should always be considered in patients with a pelvic mass especially in ones using intrauterine device.

  3. Actinomycosis of the appendix mimicking appendiceal tumor:A case report

    Institute of Scientific and Technical Information of China (English)

    Sang-Yun; Lee; Hee-Jin; Kwon; Jin-Han; Cho; Jong-Young; Oh; Kyung-Jin; Nam; Jin-Hwa; Lee; Seong-Kuk; Yoon; Myong-Jin; Kang; Jin-Sook; Jeong

    2010-01-01

    Actinomycosis is an uncommon chronic infectious disease. Common sites of involvement include the cervicofacial, thoracic and abdominopelvic regions. In abdominopelvic actinomycosis, the ileocecal region, including the appendix, is the most commonly involved site. In some reports, limited appendiceal actinomycosis has revealed a thickened appendiceal wall with peri-appendiceal inflammation as acute appendicitis or perforated appendicitis. We experienced pathologically confirmed intraluminal limited appendice...

  4. Treatment of cervicofacial actinomycosis: a report of 19 cases and review of literature

    NARCIS (Netherlands)

    Moghimi, M.; Salentijn, E.; Debets-Ossenkop, Y.; Karagozoglu, K.H.; Forouzanfar, T.

    2013-01-01

    Objectives: Actinomycosis is a chronic suppurative granulomatous infection caused by the Actinomyces genus. Orocervicofacial actinomycosis is the most common form of the disease, seen in up to 55% of cases. All forms of actinomycosis are treated with high doses of intravenous penicillin G over two t

  5. [Long-lasting disease after serious genital actinomycosis in a former IUD user].

    Science.gov (United States)

    Ravn, Pernille; Staer-Jensen, Jette E; Antonsen, Annemarie

    2002-09-23

    A previous IUD user underwent surgery on suspicion of ovarian cancer. No malignancy was found and genital actinomycosis was diagnosed on the histology and a history of previously verified, but inadequately treated, actinomycosis of the internal genitals. Actinomycosis is a rare disease with a potentially high morbidity. Diagnosis is difficult, as symptoms are non-specific and culture is often negative.

  6. [Pelvic actinomycosis abscess and intrauterine device].

    Science.gov (United States)

    Ko-Kivok-Yun, P; Charasson, T; Halasz, A; Fournié, A

    1997-03-01

    A case of association between IUD and a left tubal actinomycotic abscess is presented. The 45 year old patient was wearing an IUD for five years. The symptomatology was mainly that of pelvic pain with an associated mass in the left iliac fossa. The working diagnosis was that of a digestive tumor or an adnexal mass. The surgical procedure allowed to identify an inflammatory reaction with a pseudotumoral abscess formation in the left fallopian tube. The etiology was confirmed by the pathology and bacteriology reports. Treatment consists in surgical extirpation of the infected structures and long term antibacterial therapy. Actinomycosis is a rare but potentially serious pelvic disease. It may involve various organs and readily takes on the aspect of tumor formation.

  7. Can Surgery Be Avoided? Exclusive Antibiotic Treatment for Pelvic Actinomycosis

    Science.gov (United States)

    Williams, E. M.; Markey, C. M.; Johnson, A. M.; Morales-Ramirez, P. B.

    2017-01-01

    Pelvic actinomycosis is an uncommon, slowly progressing granulomatous infection that has been associated with the presence of intrauterine devices. Due to its unspecific clinical and radiologic findings, it can mimic pelvic or intra-abdominal malignancy leading to mutilating surgery of high morbidity. Rarely, diagnosis is made preoperatively and in most cases surgical intervention is necessary. The patient in our case is a 42-year-old female with an IUD for 15 years diagnosed with pelvic actinomycosis. Patient was uniquely diagnosed preoperatively through paracentesis and treated conservatively with prolonged antibiotic therapy and without any type of surgical intervention. Follow-up at 1 year showed almost complete radiologic resolution of the inflammatory mass, nutritional recovery, and absence of symptoms. Pelvic actinomycosis can be successfully diagnosed and treated medically without surgical interventions. PMID:28299218

  8. Abdominal actinomycosis associated with intrauterine device: CT features.

    Science.gov (United States)

    Laurent, T; de Grandi, P; Schnyder, P

    1996-01-01

    Abdominal actinomycosis is a severe and progressive peritoneal infection, due to an anerobic gram-positive bacterium, Actinomyces israelii. The presence of a long-standing intrauterine device (IUD) is a well-known risk factor in young women. We report two cases of pelviperitoneal actinomycosis appearing in two young women with acute low abdominal pain. Abdominal CT demonstrated multiple solid or encapsulated peritoneal masses with marked contrast enhancement and infiltration of the adjacent mesenteric fat. Laparoscopy confirmed the presence of intraperitoneal abscesses which contained Actinomyces israelii. High doses of amoxicillin and clavulanic acid (Augmentine) were given and following CT scan after 2 and 6 weeks showed a slow, but complete, resolution of the lesions. Although the radiologic presentation of actinomycosis is nonspecific, the diagnosis should be raised in the presence of pseudotumoral mesenteric infiltration, particularly in young women with an IUD. Abdominal CT is a useful method for diagnosis and for follow-up.

  9. Actinomycosis: etiology, clinical features, diagnosis, treatment, and management

    Directory of Open Access Journals (Sweden)

    Valour F

    2014-07-01

    Full Text Available Florent Valour,1–3 Agathe Sénéchal,1,2 Céline Dupieux,2–4 Judith Karsenty,1,2 Sébastien Lustig,2,5 Pierre Breton,2,6 Arnaud Gleizal,2,7 Loïc Boussel,2,8,9 Frédéric Laurent,2–4 Evelyne Braun,1 Christian Chidiac,1–3 Florence Ader,1–3 Tristan Ferry1–3 1Service des Maladies Infectieuses et Tropicales, Hospices Civils de Lyon, Groupement Hospitalier Nord, Lyon, France; 2Université Claude Bernard Lyon 1, Lyon, France; 3Centre International de Recherche en Infectiologie, CIRI, INSERM U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France; 4Laboratoire de Bactériologie, Centre de Biologie du Nord, Hospices Civils de Lyon, Groupement Hospitalier Nord, Lyon, France; 5Chirurgie Orthopédique, Hospices Civils de Lyon, Groupement Hospitalier Nord, Lyon, France; 6Stomatologie et Chirurgie Maxillo-faciale, Hospices Civils de Lyon, Groupement Hospitalier Sud, Lyon, France; 7Chirurgie Maxillo-faciale, Hospices Civils de Lyon, Groupement Hospitalier Nord, Lyon, France; 8Radiologie, Hospices Civils de Lyon, Groupement Hospitalier Nord, Lyon, France; 9Creatis, CNRS UMR 5220, INSERM U1044, Université Lyon 1, INSA Lyon, Lyon, France Abstract: Actinomycosis is a rare chronic disease caused by Actinomyces spp., anaerobic Gram-positive bacteria that normally colonize the human mouth and digestive and genital tracts. Physicians must be aware of typical clinical presentations (such as cervicofacial actinomycosis following dental focus of infection, pelvic actinomycosis in women with an intrauterine device, and pulmonary actinomycosis in smokers with poor dental hygiene, but also that actinomycosis may mimic the malignancy process in various anatomical sites. Bacterial cultures and pathology are the cornerstone of diagnosis, but particular conditions are required in order to get the correct diagnosis. Prolonged bacterial cultures in anaerobic conditions are necessary to identify the bacterium and typical microscopic findings include necrosis with

  10. Female pelvic actinomycosis and intrauterine contraceptive devices

    Directory of Open Access Journals (Sweden)

    Faustino R Pérez-López

    2010-05-01

    Full Text Available Faustino R Pérez-López1,2, José J Tobajas1,3, Peter Chedraui41Department of Obstetrics and Gynecology, Facultad de Medicina, Universidad de Zaragoza; 2Hospital Clínico Lozano Blesa; 3Hospital Universitario Miguel Servet, Zaragoza, Spain; 4Enrique C. Sotomayor Obstetrics and Gynecology Hospital, Guayaquil, EcuadorAbstract: Female genital Actinomyces infection is relatively rare, although strongly related to long-lasting intrauterine contraceptive device (IUD application. An infective pathway has been postulated extending upward from the female perineum to the vagina and cervix. The traumatic effect of the device and a prior infection may contribute to the Actinomyces infection in the female genitalia. This disease is characterized by local swelling, suppuration, abscess formation, tissue fibrosis, tubal-ovarian mass and fistula formation. The infection spreads by contiguity often mimicking the characteristics of a malignant neoplastic process. Currently there is no consensus regarding diagnosis and screening tests, although there seems to be agreement in relation to IUD type, duration, and sexual behavior as major risk factors.Keywords: contraception, intrauterine contraceptive device, pelvic actinomycosis, sexuality

  11. A case of isolated hepatic actinomycosis causing right pulmonary empyema

    Institute of Scientific and Technical Information of China (English)

    Gonenc Kocabay; Atahan Cagatay; Haluk Eraksoy; Betul Tiryaki; Aydin Alper; Semra Calangu

    2006-01-01

    @@ The clinical picture of actinomycosis was first described in 1878.1 Actinomvcosis agents are found in the natural flora of the oral cavity, upper gastrointestinal system and female genital systems.Actinomyces israelii is usually responsible for the infections and causes chronic suppurative and granulomatous infections.1 The most common disease form is cervicofascial infection.

  12. Primary Vesical Actinomycosis in a 23-Year-Old Man

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    Tevfik Ziypak

    2014-01-01

    Full Text Available Introduction. Actinomycosis can affect any organ of the body, although cutaneous fistulas are common in actinomycotic infections, and other organs such as the bladder are only rarely involved. Case Presentation. Herein we report and discuss a young male patient with primary vesical actinomycosis. A 23-year-old man was hospitalized complaining of intermittent gross hematuria over a 6-month duration. The patient underwent a cystoscopic examination under general anesthesia; an edematous, hyperemic, wide-based mass, which protruded from the dome of the bladder, was seen and incompletely resected. The histopathological examination of the material showed Actinomyces organisms surrounded by inflammation and a photomicrograph showed the microorganism. After confirmation of bladder actinomycosis, the patient received penicillin. A CT scan of the abdomen and pelvis showed no evidence of the mass at the postoperative 6th month. Cystoscopic examination showed complete healing of the transurethral resection area at the dome of the bladder. Conclusion. In conclusion, we believe that the gold standard treatment for vesical actinomycosis should include the combination of a transurethral resection of the mass and long-term penicillin treatment.

  13. Thrombocytosis and small bowel perforation: unusual presentation of abdominopelvic actinomycosis.

    Science.gov (United States)

    Desteli, Güldeniz Aksan; Gürsu, Tvrkan; Bircan, Hüseyin Yüce; Kızılkılıç, Ebru; Demiralay, Ebru; Timurkaynak, Funda

    2013-12-15

    Intrauterine devices (IUD) are frequently used as a family planning procedure in developing countries because they are easy to administer and governmental policies support their use in many countries. It is recommended that IUDs be removed or replaced after 10 years, but longer use is common, especially in developing countries. In some cases, rare infections such as pelvic inflammatory diseases, pelvic tuberculosis, or abdominopelvic actinomycosis related to IUD can develop. Pelvic actinomycosis is a rare disease and is often diagnosed incidentally during surgery. In recent years, there has been an increase in actinomycotic infections mostly due to long-term usage of IUD and forgotten intravaginal pessaries. It usually develops as an ascending infection. It is usually associated with non-specific symptoms such as lower abdominal pain, menstrual disturbances, fever, and vaginal discharge. The disease is sometimes asymptomatic. The rate of accurate preoperative diagnosis for pelvic actinomycosis is less than 10%, and symptoms and imaging studies sometimes mimic pelvic malignancy. This report details a case with abdominopelvic actinomycosis associated with an IUD presenting with highly elevated thromboctye count and small bowel perforation with abscess formation.

  14. Preoperative diagnosis of pelvic actinomycosis by clinical cytology

    Directory of Open Access Journals (Sweden)

    Matsuda K

    2012-09-01

    Full Text Available Katsuya Matsuda,1 Hisayoshi Nakajima,2 Khaleque N Khan,1 Terumi Tanigawa,1 Daisuke Hamaguchi,1 Michio Kitajima,1 Koichi Hiraki,1 Shingo Moriyama,3 Hideaki Masuzaki11Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, 2Department of Health Sciences, Nagasaki University Graduate School of Biomedical Sciences, 3Shimabara Maternity Clinic, Nagasaki, JapanBackground: The purpose of this work was to investigate whether clinical cytology could be useful in the preoperative diagnosis of pelvic actinomycosis.Methods: This study involved the prospective collection of samples derived from the endometrium and the uterine cervix, and retrospective data analysis. Nine patients with clinically diagnosed pelvic actinomycosis were enrolled. The clinical and hematological characteristics of patients were recorded, and detection of actinomyces was performed by cytology, pathology, and bacteriological culture of samples and by imprint intrauterine contraceptive device (IUD cytology.Results: The detection rate of actinomyces was 77.7% by combined cervical and endometrial cytology, 50.0% by pathology, and 11.1% by bacterial culture.Conclusion: The higher detection rate of actinomyces by cytology than by pathology or bacteriology suggests that careful cytological examination may be clinically useful in the preoperative diagnosis of pelvic actinomycosis.Keywords: actinomycosis, cytology, pathology, intrauterine contraceptive device, pelvic inflammatory disease

  15. Actinomycosis involving the liver. Computed tomography/ultrasound correlation.

    Science.gov (United States)

    Sheth, S; Fishman, E K; Sanders, R

    1987-06-01

    The clinical profile of pelvic actinomycosis, which is being recognized with increased frequency in IUD users, can be misleading in such patients and lead to dangerous delays in diagnosis. The authors present a case in which an IUD user initially sought medical attention for multiple liver abscesses secondary to spread from unsuspected ovarian actinomycosis. The 43-year-old patient, who was admitted with right upper quadrant pain and fever, had a 15-year history of IUD use, although the device had been removed 1 year prior to admission for apparent infection in the left ovary. Ultrasound revealed mixed cystic and solid liver lesions as well as a complex subcapsular fluid collection. A solid left adnexal mass was demonstrated in the pelvis. Computed tomography scan indicated extension of 1 of the complex cystic liver lesions through the liver capsule and into the abdominal wall. Needle aspirations of the liver lesions yielded thick pus that was later identified as Actinomyces israelii. Actinomycosis was evident in the ovarian lesion. Colonization of the vagina and uterus by actinomycosis has been reported by 1.6-5.3% of IUD users, and the risk appears to increase when the same IUD is used for a prolonged time period. In this case, neither the computed tomography scan nor ultrasound suggested an inflammatory process of the left ovary. Aspiration of a liver lesion under ultrasound guidance was necessary for the correct diagnosis. Since actinomycosis has the potential to spread to extrapelvic organs such as the peritoneum, liver, and brain, early diagnosis is essential.

  16. Ovarian and vesical actinomycosis: a case report and literature review.

    Science.gov (United States)

    Hwang, Jong Ha; Hong, Jin Hwa; Lee, Jae Kwan

    2009-04-01

    We present a patient with a tubo-ovarian abscess pathologically confirmed to be actinomycosis in a 44-year-old woman with an intrauterine device (IUD). An ultrasound showed that the IUD was imposed on an apparently degenerated myoma. A pelvic MRI was performed to differentiate the uterine findings from a sarcoma. The MRI showed a heterogeneous pelvic mass and a bladder mass suggesting chronic inflammation caused by an organism such as actinomycosis. An exploratory laparotomy was performed, which revealed a right tubo-ovarian mass with abscess formation as well as a bladder mass. A subtotal hysterectomy, right salpingoophorectomy, partial cystectomy, and appendectomy were performed in addition to drainage of the abscess. Histopathological examination revealed a tubo-ovarian abscess and a bladder mass with colonies of actinomycoses.

  17. Abdominal actinomycosis associated with intrauterine device: CT features

    Energy Technology Data Exchange (ETDEWEB)

    Laurent, T. [Dept. of Radiology, CHUV-1011, Lausanne (Switzerland); Grandi, P. de [Dept. of Gynecology-Obstetrics, CHUV-1011, Lausame (Switzerland); Schnyder, P. [Dept. of Radiology, CHUV-1011, Lausanne (Switzerland)

    1996-10-01

    We report two cases of pelviperitoneal actinomycosis appearing in two young women with acute low abdominal pain. Abdominal CT demonstrated multiple solid or encapsulated peritoneal masses with marked contrast enhancement and infiltration of the adjacent mesenteric fat. Laparoscopy confirmed the presence of intraperitoneal abscesses which contained Actinomyces israelii. High doses of amoxicillin and clavulanic acid (Augmentine) were given and following CT scan after 2 and 6 weeks showed a slow, but complete, resolution of the lesions. Although the radiologic presentation of actinomycosis is nonspecific, the diagnosis should be raised in the presence of pseudotumoral mesenteric infiltration, particularly in young women with an IUD. Abdominal CT is a useful method for diagnosis and for follow-up. (orig./MG)

  18. Pelvic actinomycosis with tuboovarian invelvement mimicking ovarian neoplasm: Case report

    OpenAIRE

    2010-01-01

    Actinomycosis is a chronic, suppurative, granulomatous bacterial infection caused by Actinomyces Israeli with rarely involment of pelvis. However, it is a clinical entity that its relationship with the conditions of facilitated access of microorganisms to pelvis such as intrauterine devices, well-defined. It can be diagnosed before they becoming symptomatic, with the seeing actinomyces-like organisms in routine Pap smear screening of intrauterine device users. But, in patients who have not th...

  19. Pelvic actinomycosis in association with an intrauterine device.

    Science.gov (United States)

    Garland, S M; Rawling, D

    1993-02-01

    A case of pelvic actinomycosis is described which occurred in association with the use of an intrauterine device (IUD). Initially medical management alone was used, but surgical intervention was necessitated for multiple pelvic abscesses. We would strongly recommend that any IUD be removed should it be associated with actinomyces on genital smears and/or culture. If sepsis is also apparent, IUD removal with use of long-term antibiotics is required.

  20. A Suspicious Pancreatic Mass in Chronic Pancreatitis: Pancreatic Actinomycosis

    Directory of Open Access Journals (Sweden)

    F. de Clerck

    2015-01-01

    Full Text Available Introduction. Pancreatic actinomycosis is a chronic infection of the pancreas caused by the suppurative Gram-positive bacterium Actinomyces. It has mostly been described in patients following repeated main pancreatic duct stenting in the context of chronic pancreatitis or following pancreatic surgery. This type of pancreatitis is often erroneously interpreted as pancreatic malignancy due to the specific invasive characteristics of Actinomyces. Case. A 64-year-old male with a history of chronic pancreatitis and repeated main pancreatic duct stenting presented with weight loss, fever, night sweats, and abdominal pain. CT imaging revealed a mass in the pancreatic tail, invading the surrounding tissue and resulting in splenic vein thrombosis. Resectable pancreatic cancer was suspected, and pancreatic tail resection was performed. Postoperative findings revealed pancreatic actinomycosis instead of neoplasia. Conclusion. Pancreatic actinomycosis is a rare type of infectious pancreatitis that should be included in the differential diagnosis when a pancreatic mass is discovered in a patient with chronic pancreatitis and prior main pancreatic duct stenting. Our case emphasizes the importance of pursuing a histomorphological confirmation.

  1. Abdominal actinomycosis: barium enema and computed tomography findings.

    Science.gov (United States)

    Uchiyama, N; Ishikawa, T; Miyakawa, K; Iinuma, G; Nakajima, H; Ushio, K; Yokota, T; Akasu, T; Shimoda, T

    1997-02-01

    A case of abdominal actinomycosis is described in a woman with recurrent right lower abdominal pain and low-grade fever without history of appendectomy. Past history included the use of an intrauterine device (IUD) until 10 years before manifestation of these symptoms. We followed up the patient, via diagnostic imaging, for 7 months. On initial barium enema, a polypoid lesion was visualized at the bottom of the cecum and there was constriction of the sigmoid colon; the appendix was not seen. Seven months later, poor extension at the cecum, severe constriction in the sigmoid colon, and narrowing of the terminal ileum were also visualized. On computed tomography (CT), the lesion was initially localized only in the ileocecal region adjacent to the sigmoid colon. After 7 months, the lesion had infiltrated adjacent anatomic components and showed direct infiltration of the pelvic space. Differential diagnosis was difficult, as it was not obvious whether this was a pelvic abscess due to inflammation or appendiceal carcinoma. Laparotomy was performed. Macroscopically, the lesion was not limited to the ileocecal region, but involved the right ureter, tubes the Fallopian and ovary, bladder, psoas muscle, and abdominal wall. Pathology findings showed, chronic inflammatory tissue with evidence of actinomycosis. Although previous reports have described a lack of specific findings in this disease. When actinomycosis is suspected, CT is recommended to define its extent.

  2. Primary omental actinomycosis as a differential diagnosis of acute appendicitis in children. Case report

    Directory of Open Access Journals (Sweden)

    Sergio Castañeda

    2016-09-01

    Full Text Available Actinomycosis is a chronic suppurative granulomatous inflammation caused by Actinomyces species. Abdominal actinomycosis is a rare condition, with very low incidence in childhood, and usually associated to trauma or perforation of hollow viscera. We are presenting a case of a ten-year-old boy with omental actinomycosis mimic and appendiceal infection, without a history of trauma or perforation, suggesting a hemmatogen spread. The complete resection of the affected tissue may warrant a cure in spite of a short antibiotic curse.

  3. [Infiltrating tubo-ovarian abscess in IUD-associated actinomycosis].

    Science.gov (United States)

    Franz, H B; Strohmaier, W L; Geppert, M; Wechsel, H

    1992-08-01

    We report on a case of a 55-year old patient with a great adnexal tumour (10 x 5 x 8 cm), on the left side with infiltration of the bladder and the pelvis with recurring urinary retention in the kidney. Histological examination revealed an intrauterine device-associated actinomycosis. Following a 6-month high dose penicillin therapy, the abdominal hysterectomy with adnexectomy and partial resection of the bladder with new implantation of the ureter (Boari) was performed. The postoperative period was uneventful, the urogram normal.

  4. Differentiating pelvic actinomycosis from advanced ovarian cancer: a report of two cases, management reflections and literature review

    OpenAIRE

    2014-01-01

    Pelvic actinomycosis comprises a rare, subacute to chronic bacterial infection characterised by suppurative and granulomatous inflammation. Diagnosis is difficult as it may simulate pelvic malignancies. Laboratory and radiological findings are non-specific. We reported on 2 cases of pelvic actinomycosis mimicking ovarian malignancy with different management approaches that lead to opposite outcomes. We reviewed the literature on pelvic actinomycosis imitating ovarian cancer with a focus on it...

  5. Successful treatment of pelvic actinomycosis using transgluteal drainage: A case report.

    Science.gov (United States)

    Inatomi, Ayako; Tsuji, Shunichiro; Amano, Tsukuru; Kobayashi, Masashi

    2016-08-01

    Actinomycosis is a rare chronic suppurative granulomatous infection, associated with long-term IUD placement. Standard treatment is long-term antibiotic administration. Here, we report a more radical pelvic abscess drainage treatment, because conservative therapy failed to provide relief. A 52-year-old woman (gravida 4 para 3) with an 18-year IUD history was referred to our hospital with a pelvic abscess, indicated clinically to be pelvic actinomycosis. Standard conservative penicillin therapy provided no relief. We performed transgluteal drainage, confirmed actinomycosis pathologically, administered clindamycin, and observed no relapse. Transgluteal percutaneous drainage combined with antibiotics may be useful for refractory deep pelvic abscess caused by actinomycosis and may even curtail the antibiotic administration period.

  6. Differentiating pelvic actinomycosis from advanced ovarian cancer: a report of two cases, management reflections and literature review.

    Science.gov (United States)

    Laios, Alex; Terekh, Iryna; Majd, Hooman Soleymani; Pathiraja, Pubudu; Manek, Sanjiv; Haldar, Krishnayan

    2014-01-01

    Pelvic actinomycosis comprises a rare, subacute to chronic bacterial infection characterised by suppurative and granulomatous inflammation. Diagnosis is difficult as it may simulate pelvic malignancies. Laboratory and radiological findings are non-specific. We reported on 2 cases of pelvic actinomycosis mimicking ovarian malignancy with different management approaches that lead to opposite outcomes. We reviewed the literature on pelvic actinomycosis imitating ovarian cancer with a focus on its surgical management. Despite agreement on the duration of antibiotic therapy following surgical management, consensus regarding surgical approach was rather equivocal. We concluded that pelvic actinomycosis should be strongly suspected in women with presumed ovarian cancer of atypical presentation and a history of intrauterine devices (IUD).

  7. Clinical Features of Abdominopelvic Actinomycosis: Report of Twenty Cases and Literature Review

    OpenAIRE

    2009-01-01

    Purpose Intrabdominal actinomycosis is difficult to diagnose preoperatively. This chronic infection has a propensity to mimic many other diseases and may present with a wide variety of symptoms. The aim of this study was to evaluate the characteristic clinical features with review of the literature. Materials and Methods We retrospectively analyzed 22 patients with intrabdominal actinomycosis between January 2000 and January 2006. Results There were two men and 20 women with a mean age of 42....

  8. IUD-associated ovarian actinomycosis causing bowel obstruction.

    Science.gov (United States)

    Maroni, E S; Genton, C Y

    1986-01-01

    This case report presents an unusual case of primary IUD-associated ovarian actinomycosis, which spread to the sigmoid causing intestinal obstruction. A 43-year-old gravida 3, para 2, had her 1st IUD from 1978-80 (Gyne-T) and her 2nd IUD from 1980 to October 1983 (Multiload). Right lower abdominal pain led to hospitalization in May 1983. A tender nodular mass was palpated in the left pelvic area. Laboratory results confirmed the presence of inflammation. Rapid improvement followed a course of laxatives and cephalosporin antibiotics, and the patient was discharged with the diagnosis of acute sigmoid diverticulitis. 2 months later, a double contrast examination of the large intestine was done and showed severe narrowing of the sigmoid colon over a distance of 12 cm and occasional sharp recesses. Colonoscopy showed a spastic stricture of the sigmoid with massive edema of the otherwise intact mucosa at 18 cm. Computer tomography of the abdomen showed a large, focally cystic infiltrative mass in the pelvis with congestion and displacement of both ureters as well as bilateral hydronephrosis, predominantly on the right side. The descending colon was congested. The patient was readmitted to hospital with the tentative diagnosis of ovarian cancer when her general condition deteriorated. She complained again of abdominal pain in the right lower quadrant and alternating diarrhea and constipation. Pyrexia and the hematological findings suggested sepsis. The pelvis contained a predominantly leftsided nodular mass and a brown fetid discharge was coming through the cervix. The IUD was removed and treatment with ampicillin and clindamycin was started with rapid improvement in the patient's condition. Obstruction with extreme distention of the colon required emergency laparotomy. An inflammatory mass was found in the pelvis consisting of a right-sided ovarian tumor, bilateral hydrosalpinges, and a tightly encased sigmoid colon. The dilated caecum had a large necrotic area in its

  9. IUD-associated pelvic actinomycosis: a report of five cases.

    Science.gov (United States)

    Müller-Holzner, E; Ruth, N R; Abfalter, E; Schröcksnadel, H; Dapunt, O; Martin-Sances, L; Nogales, F F

    1995-01-01

    Five cases of intrauterine device (IUD)-associated tuboovarian actinomycosis are presented. The patients' ages ranged from 33 to 49 years and their IUD usage from 2 to 12 years. Clinical features of the cases included stenosis of the sigmoid colon in 4 cases, ureteric or bladder obstruction in two cases, and rectal fistula in a further instance. All patients were successfully treated postoperatively with penicillin or ampicillin. An initial diagnosis of ovarian carcinoma was considered in all cases. Although Actinomyces is difficult to differentiate histopathologically from microorganisms and other substances that cause the Splendore-Hoeppli phenomenon, morphological diagnosis permits a quicker and more practical approach than bacterial cultures in the establishment of postoperative antibiotic treatment. Intraoperative frozen-section diagnosis of an acute inflammatory process permits the surgeon to make an immediate decision in order to avoid extensive surgery when ovarian carcinoma is suspected.

  10. [Tumorous actinomycosis of the pelvis with in situ intrauterine device].

    Science.gov (United States)

    Bilek, K; Horn, L C; Schinagl, A

    1993-11-01

    The case is described of a 53-year old woman who had given birth three times and had undergone one abortion. After she was treated as an outpatient because of back pain in the lower waist area suppuration occurred from a fistula laterally right to the sacral bone in the area of the buttocks triangle, which persisted even after several outpatient surgical interventions. In addition, she had experienced a weight loss of 24 kg. At admission she had a temperature of 39 degrees Celsius, anemia, and leukocytosis. Sonography indicated slight hepatomegaly, hydroureter, right-sided hydronephrosis, and an right ovarian cyst of 4 cm size. Computer tomography showed a blurry structure that extended from the right kidney pole along the M. iliopsoas caudally up to the small pelvis, pressing against the organs caudally-ventrally, which also broke through dorsally between the lumbar region vertebrae and pelvis in the gluteal region percutaneously. The process was categorized as a frank paranephritis prolapsus abscess. Cessation of urine was determined. Laparotomy was carried out because of the suspicion of an inflammatory adnexal disease with parametritis. The uterus, including both adnexa as well as the conglomeration tumor, were removed. In the uterine cavity a Dana Cor IUD was found that had been inserted 13 years before and forgotten by the patient. At the site of the right adnexum there was a tumor (9 x 6 x 5 cu. cm) as well as a tube changed by inflammation (7 x 1.5 sq. cm). On the right side there was unspecific, suppurative salpingitis and in the ovary an abscess formation on the grounds of actinomycosis. On the left side there was only a suppurative inflammation of the tube without actinomycosis sediment. Immediately a high-dose antibiotic therapy (Penicillin G, 10 million IU) was started, lasting for 1 year. The kidney cessation with the back complaints rapidly disappeared. The cutaneous fistulae healed with scarring, however, a fully normal right-sided kidney function

  11. [Abdomino-pelvic actinomycosis associated with an intrauterine device. Apropos of a case].

    Science.gov (United States)

    Domecq, G; Mendoza, E; Docobo, F; Lozano, M; Gavilan, F; Fernández Dovale, M

    1982-05-01

    Although over 300 cases of pelvic actinomycosis have been published, it was not until 1973 that the 1st case of pelvic actinomycosis associated with the new generation of IUDs was described. Data is provided in this article on the causative agent, laboratory procedures, surgical excision, and pathological studies in 1 case of abdominal-pelvic actinomycosis, and the findings are compared to other reports in the English and Spanish literature. A multipara of 25 years with fever, metrorrhagia, and painful tumoration began to suffer dysmenorrhea in June 1980 but attributed the symptoms to the Copper 250 Multiload IUD she had used since July 1979. A laparotomy in December 1980 disclosed the infection, and pathological tests confirmed the diagnosis. The exact incidence of the association of actinomycosis and the IUD is not known, but the microorganism, Actinomyces-Israeli, is more common in wearers of IUDs than in other women. The diagnosis of actinomycosis is confirmed through microbiological study and histological identification. Treatment since 1945 has consisted of large doses of penicillin over long periods of time, but the use of other antibiotics including tetracycline and erythromycin has been introduced. The abscess or abscesses should be excised and the IUD removed in cases where a relationship is suspected.

  12. Pulmonary actinomycosis: a case undergoing resection through video-assisted thoracic surgery (VATS)

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Actinomycosis is an uncommon disease, which is usually manifested as cervicofacial infection and related to poor oral hygiene or compromised immune function. Pulmonary actinomycosis is rare, but its diagnosis is changing due to its variable presentation and the similarity in appearance to other intrapulmonary diseases. Here we report an 80-year-old man with a solitary pulmonary nodule over the left upper lobe. Pulmonary neoplasm was highly suspected in this patient and thus resection of the mass was undertaken through video-assisted thoracic surgery (VATS). Histopathological examination demonstrated this patient had an Actinomyeces infection. While the application of VATS in patients with pulmonary actinomycosis has rarely been reported in literature, we conclude that VATS is valuable for the diagnosis and treatment of patients with undetermined pulmonary nodule(s).

  13. Mycotic pulmonary artery aneurysm as an unusual complication of thoracic actinomycosis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyung-Soo; Lee, Sang-Yeub [Wonkwang University College, Iksan (Korea, Republic of); Oh, Yu-Whan; Noh, Hyung-Jun; Lee, Ki-Yeol; Kang, Eun-Young [Korea University Hospital and Korea University College, Seoul (Korea, Republic of)

    2004-03-15

    Although pulmonary artery aneurysms are a rare vascular anomaly, they are seen in a wide variety of conditions, such as congenital heart disease, infection, trauma, pulmonary hypertension, cystic medial necrosis and generalized vasculitis. To our knowledge, mycotic aneurysms caused by pulmonary actinomycosis have not been reported in the radiologic literature. Herein, a case of pulmonary actinomycosis complicated by mycotic aneurysm is presented. On CT scans, this case showed focal aneurysmal dilatation of a peripheral pulmonary artery within necrotizing pneumonia of the right lower lobe, which was successfully treated with transcatheter embolization using wire coils.

  14. [Genital actinomycosis, following insertion of intra-uterine device (IUD) -- possibilities for prevention (author's transl)].

    Science.gov (United States)

    Szabo, L G; Esztergaly, S; Dzvonyar, I

    1981-01-01

    Occurrence of actinomyces infection, following IUD insertion, was observed by the authors in two cases. A pathogenetic role has been positively ascribed to the IUD. In one case, actinomycosis was histologically confirmed on a surgically removed and accompanied by severe tuberculoid tissue reaction. In the second case, actinomyces colonies were recorded and identified from the IUD which had been removed for adnexitis. Good success was obtained by early medication. Prevention and early detection will be possible by vaginal smears prior to insertion of an IUD and with the latter in place, after some time, as well as by testing the IUD proper for actinomycosis, after its removal.

  15. Pelvic actinomycosis associated with use of intrauterine device: a new challenge for the surgeon.

    Science.gov (United States)

    Doberneck, R C

    1982-01-01

    Pelvic actinomycosis associated with the use of an intrauterine device (IUD) is a recently recognized combination. The usual manifestation of the disease are those of mild pelvic inflammatory disease (PID) in a woman who uses an IUD. The disease is easily recognized on Papanicolaou-stained cervicovaginal smears. Early treatment involves removal of the IUD and administration of penicillin. Rarely, the disease may be serious and may require drainage of intra-abdominal abscesses, hysterectomy with salpingo-oophorectomy, or both. The second known death from pelvic actinomycosis associated with use of an IUD is reported.

  16. [Actinomycosis of the minor pelvis associated with prolonged use of intrauterine contraceptive devices (IUD)].

    Science.gov (United States)

    Durdević, S; Vejnović, T; Novakov, A

    1993-01-01

    Pelvic actinomycosis is a rare disorder caused by Gram-positive anaerobic bacteria Actinomyces Israeli, and it is commonly associated with the prolonged use of IUD. The authors present two cases of pelvic actinomycosis in patients who used IUD for prolonged periods of time (eight and fourteen years). The diagnostic procedure in both cases lasted long and the definite diagnosis was made only after the pathohistological examination of the material taken during the surgical treatment. Actinomyces Israeli should be considered as one of the causes of the diagnosed pelvic inflammation especially when it is associated with the prolonged use of IUD.

  17. Actinomycosis Presenting as an Abdominal Mass in a Child

    Directory of Open Access Journals (Sweden)

    Rahsan Özcan

    2011-03-01

    Full Text Available Abdominal actinomycosis in childhood period is very rare and a relation to trauma is not well established. Herein we report a case that appeared subsequent to abdominal trauma. A 17 years old boy presented with left lower quadrant abdominal mass and signs of acute abdomen. The symptoms of abdominal discomfort began after a fall from height 3 months before admission. There were signs of acute abdomen at physical examination. Ultrasound of abdomen demonstrated a mass; CT scan findings pointed to a suspicious “internal hernia”. An emergency laparotomy was performed. During surgery, a mass located over sigmoid colon and infiltrating the lateral abdominal wall was found. It was removed en bloc with the adjacent omentum. Except for the thickened sigmoid colon, no other pathologies were present at laparotomy. The pathology specimen revealed the actinomyces infection. The patient was treated with oral penicillin after discharge and the follow-up was uneventful. We advocate, keeping the actinomyces infection in mind in cases presenting with abdominal mass of unknown origin in childhood period.

  18. Intra-Abdominal Actinomycosis Mimicking Malignant Abdominal Disease

    Directory of Open Access Journals (Sweden)

    Ali Ridha

    2017-01-01

    Full Text Available Abdominal actinomycosis is a rare infectious disease, caused by gram positive anaerobic bacteria, that may appear as an abdominal mass and/or abscess (Wagenlehner et al. 2003. This paper presents an unusual case of a hemodynamically stable 80-year-old man who presented to the emergency department with 4 weeks of worsening abdominal pain and swelling. He also complains of a 20-bound weight loss in 2 months. A large tender palpable mass in the right upper quadrant was noted on physical exam. Laboratory studies showed a normal white blood cell count, slightly decreased hemoglobin and hematocrit, and mildly elevated total bilirubin and alkaline phosphatase. A CT with contrast was done and showed a liver mass. Radiology and general surgery suspected malignancy and recommended CT guided biopsy. The sample revealed abundant neutrophils and gram positive rods. Cytology was negative for malignancy and cultures eventually grew actinomyces. High dose IV penicillin therapy was given for 4 weeks and with appropriate response transitioned to oral antibiotic for 9 months with complete resolution of symptoms.

  19. Intra-Abdominal Actinomycosis Mimicking Malignant Abdominal Disease

    Science.gov (United States)

    Oguejiofor, Njideka; Al-Abayechi, Sarah; Njoku, Emmanuel

    2017-01-01

    Abdominal actinomycosis is a rare infectious disease, caused by gram positive anaerobic bacteria, that may appear as an abdominal mass and/or abscess (Wagenlehner et al. 2003). This paper presents an unusual case of a hemodynamically stable 80-year-old man who presented to the emergency department with 4 weeks of worsening abdominal pain and swelling. He also complains of a 20-bound weight loss in 2 months. A large tender palpable mass in the right upper quadrant was noted on physical exam. Laboratory studies showed a normal white blood cell count, slightly decreased hemoglobin and hematocrit, and mildly elevated total bilirubin and alkaline phosphatase. A CT with contrast was done and showed a liver mass. Radiology and general surgery suspected malignancy and recommended CT guided biopsy. The sample revealed abundant neutrophils and gram positive rods. Cytology was negative for malignancy and cultures eventually grew actinomyces. High dose IV penicillin therapy was given for 4 weeks and with appropriate response transitioned to oral antibiotic for 9 months with complete resolution of symptoms. PMID:28299215

  20. Primary hepatic actinomycosis mimicking a tumor (inflammatory pseudotumor: Case report and literature review

    Directory of Open Access Journals (Sweden)

    Ayşe Batirel

    2015-06-01

    Full Text Available Actinomycosis often manifests with abscesses in the cervicofacial region. Hepatic involvement occurs usually secondary to an intraabdominal infection. “Isolated or primary hepatic actinomycosis (PHA defines actinomycosis in which the source of infection cannot be demonstrated elsewhere. Herein, we aimed to highlight hepatic actinomycosis in the differential diagnosis of hepatic mass lesions, and also its occurrence even in patients without underlying risk factors. A 24-year-old man, who presented with epigastric and right-upper-quadrant abdominal pain, fever, weight loss, and had a tumor-like mass in the liver was admitted to our hospital. He had no predisposing risk factors or comorbidities. We reviewed all the cases with PHA, who had no predisposing risk factors, in English medical literature from 1993 to 2014. Actinomycotic hepatic pseudotumors should be considered in the differential diagnosis of solitary liver lesions even in patients without any predisposing factors. Multi-disciplinary approach is important in the diagnosis and management. J Microbiol Infect Dis 2015;5(2: 79-84

  1. [Adnexal actinomycosis in a woman using an intrauterine contraceptive device (IUD)].

    Science.gov (United States)

    Pawlina, W; Bogdanowicz, M

    1987-01-01

    The case-study of genital actinomycosis in a 33-year old woman wearing a "Copper T200" IUD is presented. She was hospitalized and treated for lower abdominal pain and non-characteristic signs of adnexitis twice. Adnexectomy on the left side was performed to remove an orange-size cyst. Histo-pathological examination of a prepared tissue sample revealed a colony of Actinomyces. Following the operation the patient was treated with 3 x 500 mg Flagyl (metronidazole) 3 x 80 mg of Gentamicin im. The wound healed in 19 days after operation. This woman had worn the IUD continuously for more than 3 years, thus there was an increased risk of uterine lesions. The most frequent consequences of wearing IUDs for a long time are dysmenorrhea and endometritis and therapeutic approaches are detailed. Since its first description in the literature in 1857 actinomycosis has not been mentioned frequently. However, with the spread of IUDs, the number of actinomycosis-like cases has increased and this justifies the need for improved diagnosis. The frequency of actinomycosis occurring in women wearing IUDs ranges between 1.6% and 19.7%

  2. [Pseudotumoral pelvic actinomycosis in a woman who had been using an IUD for 15 years].

    Science.gov (United States)

    Ben Nasr, R; Ben Othman, M; Cammoun, M

    1989-01-01

    A 56-year-old woman was referred to a hospital in Tunis for a tumor of the right ovary. The patient had had 11 term pregnancies and had been using an IUD with no medical supervision for 15 years. She complained of recent constipation and weight loss. The uterus was of normal size but of hard consistency and fixed to the sacrum. A cervical smear was normal. The patient was found to be anemic and the sedimentation rate was accelerated. A diagnosis of probably malignant tumor of the right ovary was made and a hysterectomy with bilateral ovarectomy was performed after laparotomy. The patient left the hospital after receiving a prescription for ampicillin and was lost to follow-up. Histological examination showed the mass to be comprised of inflammatory fibrous and granulomatous tissue with numerous abscesses of a filamentous, strongly eosinophilic character suggesting actinomycosis. Pelvic actinomycosis is a rare chronic infection caused by a gram positive anaerobic bacteria, Actinomyces Israeli. The clinical signs usually include anemia, weight loss, and pelvic mass. Clinical diagnosis is difficult, and diagnosis is usually based on histological and bacteriologic examination. Observation of the symptoms in association with IUD use suggests actinomycosis. The treatment of choice combines surgery with antibiotic therapy for 2 months. Cervical smears should be regularly scheduled for IUD users not only to screen for prenoplastic and neoplastic lesions but to indicate actinomycosis at an early stage when treatment will allow serious complications to be avoided.

  3. Intrauterine contraceptive device-associated pelvic actinomycosis caused by Actinomyces urogenitalis.

    Science.gov (United States)

    Elsayed, S; George, A; Zhang, K

    2006-04-01

    We report a case of intrauterine contraceptive device (IUD) associated pelvic actinomycosis due to Actinomyces urogenitalis in a previously healthy young adult woman. Diagnosis was confirmed by 16S ribosomal RNA gene sequencing of bacterial colonies growing from the extracted device. This is the first documented report of human infection caused by this micro-organism.

  4. A Retrospective Study of Pulmonary Actinomycosis in a Single Institution in China

    Institute of Scientific and Technical Information of China (English)

    Xue-Feng Sun; Peng Wang; Hong-Rui Liu; Ju-Hong Shi

    2015-01-01

    Background:Actinomycosis is a rare indolent infectious disease caused by Actinomyces.Although pulmonary actinomycosis is thought to be more prevalent in developing countries,data from developing countries are scanty.This study was to reveal the current situation of pulmonary actinomycosis in developing countries and the difference from that in developed countries.Methods:Patients fulfilling the inclusion criteria for pulmonary actinomycosis from Peking Union Medical College Hospital in China between January 2003 and December 2014 were retrospectively analyzed.Baseline characteristics,clinical symptoms,underlying diseases,diagnostic methods,pulmonary function test results,chest computed tomography (CT) tests,fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) tests,initial diagnosis,treatment and prognosis were retrieved from medical records and analyzed.Results:Twenty-six patients were included in this study (mean age 52.0 + 13.1 years).The ratio of male to female was 1.17:1.Most common clinical symptoms were cough (15/26),sputum (12/26) and hemoptysis (12/26).Chest CT findings presented as masses (13/26),nodules (10/26) and infiltrates (3/26).FDG-PET had an increased standardized uptake value and 4/6 patients were misdiagnosed as malignancy.Many kinds of antibiotics were used in the treatment of pulmonary actonomycosis and all got favorable results.Five patients receiving complete resection of the lesion were cured without postoperative use of antibiotic.Conclusions:Pulmonary actinomycosis is a rare disease even in developing countries,and both misdiagnosis and missed diagnosis are common.FDG-PET seems useless in the differential diagnosis,and complete resection of the pulmonary lesion without postoperative antibiotic therapy might be enough to achieve cure.

  5. Abdominopelvic actinomycosis in three different locations with invasion of the abdominal wall and ureteric obstruction: An uncommon presentation

    OpenAIRE

    2015-01-01

    Introduction: Actinomycosis is a rare chronic infectious disease caused by Gram-positive anaerobic bacteria that normally colonize the bronchial system and gastrointestinal tract in humans. The most common diseases associated with actinomycosis are orocervicofacial, thoracic and abdominal infections involving Actinomyces israelii. Due to its rarity, its various clinical presentations and often-infiltrative characteristics in radiological imaging, it can easily be mistaken for other clinical c...

  6. Pelvic Actinomycosis; the Disease for Which Diagnostic and Therapeutic Delay is Still Being Experienced

    Directory of Open Access Journals (Sweden)

    Dinc Suren

    2014-03-01

    Full Text Available Actinomyces is a gram-positive bacteria, which presents as a normal flora member at mucosal areas. Because of its unexpected localization, malignancy is the clinical prediagnosis for more than half of the pelvic cases, and unnecessary extended surgery is performed in these patients. In this report, we present a case of a premenopausal woman with an abdominal mass, who had a pre-operative diagnosis of malignancy, but a post-operative histopathologic diagnosis of pelvic Actinomycosis. Although the clinical appearance resembles a malignancy, for the patient with intrauterine device (IUD history, distinctive aspect of the pelvic Actinomycosis should absolutely be considered. After the diagnosis is established, the infection source IUD should be removed and long term high dose penicillin therapy should be administered.  Surgery should be considered only if malignancy cannot be certainly excluded, if abscess drainage is necessary and if necrotic tissues and sinuses should be removed

  7. [Abdominal-pelvic actinomycosis with urinary tract involvement, secondary to gynecologic infection caused by intrauterine device].

    Science.gov (United States)

    Pérez García, M D; Rodríguez Alonso, A; Núñez López, A; Ojea Calvo, A; Alonso Rodrigo, A; Rodríguez Iglesias, B; Barros Rodríguez, M; Benavente Delgado, J; González-Carreró Fojón, J; Nogueira March, J L

    2000-02-01

    Abdomino-pelvic actinomycosis is a condition caused by Actinomyces israelii, a Gram-positive opportunistic bacteria that triggers and develops the infection only in previously injured tissues, and then slowly progresses and spreads until it extrinsically affects the urinary tract. Use of an intrauterine device is a known risk factor to suffer from this disease. Relative risk in IUD users is two- to four-fold higher compared to IUD non-users. Risk increased with prolonged IUD use. Treatment is by removal of the causative agent, surgical resection of necrotic tissues and administration of intravenous Penicillin G, 4 million units every 4 hours for 30 days, followed by Amoxicillin 500 mg every 8 hours for 12 months. This paper contributes two cases of abdomino-pelvic actinomycosis with urinary tract involvement in IUD users. Standard treatment was employed with good evolution.

  8. Intrauterine device--associated pelvic actinomycosis: a rare disease mimicking advanced ovarian cancer: a case report.

    Science.gov (United States)

    Kirova, Y M; Feuilhade, F; Belda-Lefrère, M A; Le Bourgeois, J P

    1997-01-01

    A case report of intrauterine device (IUD)-associated tubo-ovarian actinomycosis is presented. The patient was a 37-year-old nulliparous woman with IUD usage for the last four years. She presented anemia and weight lost of 8 kg. Ultrasound and computed tomography showed an unilateral large mass in the right adnexum adherent to the uterus and compressing the urinary bladder. Preoperative diagnosis of ovarian cancer with liver metastases was made. Bilateral salpingoophorectomy and total abdominal hysterectomy were performed. After pathological and biological analyses, actinomycosis was diagnosed and the patient was treated postoperatively with penicillin. The purpose of this article is to add to the literature a new case of this rare disease which clinically mimics ovarian cancer.

  9. [Intrauterine device and pelvic tumor: two case reports of pelvic actinomycosis with pseudotumor from tropical zones].

    Science.gov (United States)

    Abid, M; Ben Amar, M; Damak, Z; Feriani, N; Guirat, A; Khebir, A; Mzali, R; Frikha, M F; Beyrouti, M I

    2010-06-01

    Pelvic actinomycosis is a rare chronic disease caused by actinomycete species. The pseudotumorous form is the most common and often leads to misdiagnosis. The purpose of this report is to describe two cases of pelvic actinomycosis involving women with a history of intrauterine contraceptive device (IUD) use. Diagnosis was based on pelvic mass and the findings of surgery undertaken for suspicion of an advanced ovarian tumor with hepatic metastasis in one case and for a tumor of the right ovary in the other case. Diagnosis was confirmed by histological examination of a biopsy specimen in the first case and of the surgical specimen (right ovariectomy) in the second case. Long-term antibiotic therapy was effective in both patients. Based on these two cases and review of the literature, discussion focuses on diagnostic pitfalls, natural course, and therapeutic options for this particular infection.

  10. [Primary actinomycosis of the abdominal wall. Description of 2 cases and review of the literature].

    Science.gov (United States)

    García García, J C; Núñez Fernández, M J; Cerqueiro González, J M; García Martín, C; Rodríguez García, J C; Anibarro García, L; de Lis Muñoz, J M; Piñeiro Gómez-Durán, L

    2001-02-01

    We report two cases of isolated abdominal wall actinomycosis and review 18 previously reported cases to further characterize the clinical findings and the therapeutic management of this syndrome. This diagnosis would be advocated in patients with a palpable abdominal mass of subacute appearance with a previous history of digestive medical illness, diabetes, abdominal surgery, or prolonged IUD use. In contrast with other actinomycosis locations, remarkable data were a more elevated mean age of patients; a female predominance; a prevalent location of mass in abdominal lower left quadrant; and a shorter duration of symptomatology before to diagnosis. The CT is the first choice for imaging study and percutaneous needle aspiration would be recommended for definite diagnosis. The long-term antibiotic therapy, with or without percutaneous drainage, is the first treatment choice because is very effective and made unnecessary a more invasive surgical management. The prognosis is excellent with adequated treatment.

  11. Pulmonary actinomycosis: CT studies of diagnostic and post-treatment findings

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Su Jung; Song, Sun Wha; Bo, Seal Hwang; Park, Hyun Jin; Kim, Hyeon Sook; Kim, Ki Jun; Kim, Horrim; Park, Seog Hee [College of Medicine, the Catholic University of Korea, Uijeongbu (Korea, Republic of)

    2008-05-15

    To investigate the value of the computed tomography (CT) in the study of diagnostic and post-treatment findings of pulmonary actinomycosis. Clinical data and CT findings were retrospectively analyzed in 10 patients with histopathologically confirmed pulmonary actinomycosis. We analyzed the initial CT findings in search of patterns and distributions which suggest possible lung abnormalities and found the pleura, chest wall, and lymphadenopathy to be involved as part of the indicators of lung abnormalities. We analyzed follow-up CT findings for changes in the lungs after antibiotic therapy and recurrence after surgery. Of the 10 patients analyzed by CT for lung lesions, seven had been diagnosed with alcoholism and nine were male. The initial CTs (n = 10) indicated that all the pulmonary lesions were solitary without chest wall involvement. However, a transfissural extension was observed in 20% of the study population (n = 2). Furthermore, peripheral lung distribution and adjacent pleural thickening was observed in 70% of the study population (n = 7). Within the consolidation (n = 6) or mass (n = 4), a central low density with peripheral enhancement was seen in 70% of the study population (n = 7). A follow-up CT of the seven cases following antiobiotic therapy revealed that four cases showed minimal improvement or aggravation of their lung lesions, whereas three cases showed resolution or improvement. The improvement of the central low density was related to the improvement of consolidation or mass. Furthermore the presence of fibrosis was observed after the resolution of pulmonary lesions (n = 2). No relationship was found between the duration and response of antibiotic therapy. A follow-up CT (n = 4) subsequent to a lung resection revealed the onset of chest wall actinomycosis and a thickened pleura in one case. The results of this study highlight the value of the CT in pulmonary actinomycosis in order to diagnose and evaluate antibiotic responses, complications, or

  12. Pelvic actinomycosis presenting as a malignant pelvic mass: a case report

    Directory of Open Access Journals (Sweden)

    Perek Asiye

    2011-01-01

    Full Text Available Abstract Introduction Pelvic actinomycosis constitutes 3% of all human actinomycosis infections. It is usually insidious, and is often mistaken for other conditions such as diverticulitis, abscesses, inflammatory bowel disease and malignant tumors, presenting a diagnostic challenge pre-operatively; it is identified post-operatively in most cases. Here we present a case that presented as pelvic malignancy and was diagnosed as pelvic actinomycosis post-operatively. Case presentation A 48-year-old Caucasian Turkish woman presented to our clinic with a three-month history of abdominal pain, weight loss and difficulty in defecation. She had used an intra-uterine device for 16 years, however it had recently been removed. The rectosigmoidoscopy revealed narrowing of the lumen at 12 cm due to a mass lesion either in the wall or due to an extrinsic lesion that prevented the passage of the endoscope. On examination, there was no gynecological pathology. Magnetic resonance imaging showed a mass, measuring 5.5 × 4 cm attached to the rectum posterior to the uterus. The ureter on that side was dilated. Surgically there was a pelvic mass adhered to the rectum and uterine adnexes, measuring 10 × 12 cm. It originated from uterine adnexes, particularly ones from the left side and formed a conglomerated mass with the uterus and nearby organs; the left ureter was also dilated due to the pelvic mass. Because of concomitant tubal abscess formation and difficulty in dissection planes, total abdominal hysterectomy and bilateral salphingo-oophorectomy was performed (our patient was 48 years old and had completed her childbearing period. The cytology revealed inflammatory cells with aggregates of Actinomyces. Penicillin therapy was given for six months without any complication. Conclusions Pelvic actinomycosis should always be considered in patients with a pelvic mass especially in ones using intra-uterine devices, and who have a history of appendectomy, tonsillectomy

  13. Pelvic Actinomycosis; the Disease for Which Diagnostic and Therapeutic Delay is Still Being Experienced

    OpenAIRE

    2014-01-01

    Actinomyces is a gram-positive bacteria, which presents as a normal flora member at mucosal areas. Because of its unexpected localization, malignancy is the clinical prediagnosis for more than half of the pelvic cases, and unnecessary extended surgery is performed in these patients. In this report, we present a case of a premenopausal woman with an abdominal mass, who had a pre-operative diagnosis of malignancy, but a post-operative histopathologic diagnosis of pelvic Actinomycosis. Although ...

  14. Ovarian actinomycosis developed during the use of a plastic intrauterine contraceptive device.

    Science.gov (United States)

    Csapó, Z; Csömör, S; Zámbó, Z; Fedák, L; Vilics, G; Németh, F

    1977-01-01

    The case of a primary ovarian actinomycosis developed during the use of a Szontágh--Szereday type plastic IUD is presented. After a radical operation the patient was discharged in a good condition but 40 days later had to be readmitted because of a pelvic and abdominal wall abscess. After local surgery and massive penicillin treatment she is free of complaints. It is assumed that the IUD had a pathomechanical role.

  15. Pulmonary actinomycosis presenting with hemoptysis and a peripheral lung mass; a case report

    Directory of Open Access Journals (Sweden)

    Konstantinos Potaris

    2009-01-01

    Full Text Available SUMMARY. Pulmonary actinomycosis is a rare, chronic granulomatous disease, which is difficult to diagnose because it is commonly confused with other granulomatous infections or lung cancer. The case is reported of a 48 year-old man, a smoker, who presented with a 30 day history of productive cough with blood tinged sputum and a peripheral lung mass on the chest X-ray. He underwent full clinical and laboratory evaluation including bronchoscopy, which was unrevealing. Because of the haemoptysis the patient refused a computerized tomography (CT guided fine needle aspiration biopsy, and proceeded directly to surgery. Following a right posterolateral thoracotomy and lysis of adhesions, a wedge resection of the right lower lobe mass in the lung was performed and sent for frozen section which was negative for malignancy. His postoperative course was unremarkable. The final pathology report established the diagnosis of pulmonary actinomycosis. Pulmonary actinomycosis should be included in the differential diagnosis of a lung mass in a patient presenting with haemoptysis, because an early and accurate diagnosis will preclude unwarranted surgery. Pneumon 2009, 22(3:254-261.

  16. Actinomycosis affecting the fallopian tube and ovary: report of 3 cases, with special reference to 2 cases following IUD application.

    Science.gov (United States)

    Hsu, C T; Roan, C H; Rai, S Y; Jong, H L; Chen, T Y; Lin, Y N; Lan, C C

    1988-09-01

    Since the late 1970s, pelvic actinomycosis in association with IUD use has been a not infrequent complication in the US and Europe. In contrast, only 3 cases of pelvic actinomycosis have been reported from Taiwan over the past 40 years. IUD use was present in 2 of these cases (for 13 months and 5 years, respectively); the 3rd patient had never been an IUD user. These 3 cases were detected by sulfur granules and histology. Pathologic signs included pymetra containing pus with sulfur granules, branching of actinomyces, chronic inflammation of the bilateral fallopian tubes and ovaries, liquefaction necrosis, and tubo-ovarian abscesses. Penicillin and tetracycline were administered; the postoperative course was uneventful. The longterm presence of an IUD is believed to facilitate actinomycosis given the preexistence of other anaerobic infection or endometrial injury. In the 1 Taiwanese case where there was a history of IUD use, infection may have penetrated from the anorectum; in the 2nd such case, the intestinal route seemed likely. The low incidence of pelvic actinomycosis in Taiwan occurs against a backdrop of widespread IUD use (136,200 IUD insertions in Taiwan Province in 1986). It remains unclear whether the rarity of pelvic actinomycosis in this setting reflects underdiagnosis, life style factors, or racial differences in sexual behavior.

  17. Intracranial Complication of Rhinosinusitis from Actinomycosis of the Paranasal Sinuses: A Rare Case of Abducens Nerve Palsy

    Directory of Open Access Journals (Sweden)

    G. L. Fadda

    2014-01-01

    Full Text Available Sinonasal actinomycosis should be suspected when a patient with chronic sinusitis does not respond to medical therapy or has a history of facial trauma, dental disease, cancer, immunodeficiency, long-term steroid therapy, diabetes, or malnutrition. Radiological evaluation with computed tomography and magnetic resonance imaging are important in differential diagnosis, evaluating the extent of disease, and understanding clinical symptoms. Endoscopic sinus surgery associated with long-term intravenous antibiotic therapy is the gold standard for treatment of sinonasal actinomycosis. We report an unusual case of abducens nerve palsy resulting from invasive sinonasal actinomycosis in a patient with an abnormally enlarged sphenoid sinus. A review of the current literature highlighting clinical presentation, radiological findings, and treatment of this uncommon complication is also presented.

  18. The relationship of the intrauterine device, actinomycosis infection, and bowel abscesses.

    Science.gov (United States)

    Wagner, M; Kiselow, M C; Goodman, J J; Biever, P; Gill, L

    1979-05-01

    A case study of the injurious effect of an IUD as a contributing factor to the development of an actinomycotic infection in the female genitalia and associated abdominal viscera is reviewed. A 38-year-old white woman presented with a 2-month history of pelvic cramps, menorrhagia, and "weakness." She also complained of occasional night sweats, a 6-pound weight loss, vaginal discharge, and a low-grade fever for 6 weeks prior to admission. The patient had no significant medical history except for a calcified pelvic mass (fibroid uterus); she had had a Dalkon Shield IUD in place for several years. The patient was admitted to the hospital gynecological service for removal of the IUD, dilatation and curettage, and probable hysterectomy. Cultures were taken of the IUD and the curettings. The mass involving the rectosigmoid as well as the enlarged fibroid uterus were confirmed on pelvic examinations. The histologic diagnosis of modern squamous metaplasia was made on microscopic examination. Fungal colonies in the detritus were noted on the IUD and curettings. The pelvic mass that was palpable on examination and associated with the fibroid uterus was found to be an abscess in juxtaposition to the sigmoid colon. The operative procedure included lysis of multiple adhesions, a subtotal hysterectomy and bilateral salpingo-oophorectomy, omentectomy with a transverse colon resection leaving a proximal colostomy and a distal mucous fistula. Microscopic examination of the abscesses was diagnostic for actinomycosis. Intravenous penicillin and clindamycin were used for treatment of the actinomycosis and bacteroids that were cultured from the abscesses. The IUD, colonic abscess, fallopian tubes, uterus, transverse colon and ovaries had microscopic evidence of actinomycotic infection. Review of the world literature reveals that the papers of Barth and Tietze are the 1st to indict the IUD as an etiologic factor for actinomycosis of the female genital organs.

  19. [A case of pelvic actinomycosis in a woman as a complication of long-term IUD use].

    Science.gov (United States)

    Barwijuk, A J; Czekanowski, R

    1994-04-01

    The authors present the subsequent case of pelvic actinomycosis which occurred in woman who was using an intrauterine device for 6 years. Because of diversity of opinion, on the base of literature and own experience we propose the management of IUD users with actinomyces.

  20. Pelvic actinomycosis associated with the use of intrauterine devices. Diagnostic and therapeutic criteria.

    Science.gov (United States)

    Surico, N; Tavassoli, K; Porcelli, A; Wierdis, T

    1987-01-01

    The association between IUD use and the occurrence of pelvic infections caused by actinomyces was investigated in 221 IUD users at a University of Turin clinic. Pelvic actinomycosis is chronic and progressive, and diagnostic error and/or inappropriate treatment often lead symptoms to persist for years. Each study participant had a Papanicolaou smear both before IUD insertion and during IUD use. No Pap smear was positive for actinomyces before IUD insertion; however, during IUD use, this microorganism was identified in 30 patients (14%). There was no correlation between infection and socioeconomic status, a history of prior abortion, or IUD size. There was no significant difference between infection rates in nulliparae (12%) and primiparae (14%). Infection was found in 8% of Papanicolaou class I patients and in 15% of class II subjects. The mean duration of IUD use in women with positive Actinomyces vaginal smears was 32.1 months compared with 23.2 months for patients with negative findings. Finally, the risk of infection was higher among acceptors of plastic rather than copper IUDs. These findings confirm the association between IUD use and pelvic actinomycosis; a review of the literature reveals 395 such cases. When actinomycotic infection is discovered, immediate removal of the IUD is necessary and targetted antibiotic treatment should be commenced.

  1. The role of high mobility group box chromosomal protein 1 expression in the differential diagnosis of hepatic actinomycosis: a case report

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    Wu Chuan-Xin

    2013-01-01

    Full Text Available Abstract Introduction Primary hepatic actinomycosis is a rare disease, but is important in the differential diagnosis of hepatoma in endemic areas. As high mobility group box chromosomal protein 1 plays an important role in the pathogenesis of both acute and chronic inflammatory conditions, we postulate that high mobility group box chromosomal protein 1 may have a possible pathogenic role in hepatic actinomycosis. To the best of our knowledge, our report is the first to detect an association between highly elevated high mobility group box chromosomal protein 1 expression and hepatic actinomycosis. Case presentation A 67-year-old Chinese man was admitted to our hospital with a three-month history of epigastric pain, anorexia, and subjective weight loss. Ultrasonography and computed tomography of the patient’s abdomen confirmed a hypodense mass measuring seven cm in diameter in the left lateral segment of his liver. A hepatic tumor was suspected and surgical resection was scheduled. Histopathologic examination revealed that the overall features of the hepatic tissues were consistent with hepatic actinomycosis. Whole blood and hepatic tissue samples of the patient, of patients who had hepatocellular carcinoma and of healthy donors were collected. Serum high mobility group box chromosomal protein 1 concentration in actinomycosis was 8.5ng/mL, which was higher than the hepatocellular carcinoma level of 5.2ng/mL and the normal level of Conclusion High mobility group box chromosomal protein 1 may have a potent biological effect on the pathogenesis of hepatic actinomycosis as a novel cytokine and may be a useful marker in the differential diagnosis of hepatic actinomycosis.

  2. Actinomicose cerebral: relato de caso Actinomycosis of the brain: case report

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    ÉBER ASSIS DOS SANTOS JÚNIOR

    1999-09-01

    Full Text Available O acometimento do sistema nervoso central por actinomicetos é raro, porém apresenta bom prognóstico se diagnosticado precocemente e tratado adequadamente. Um caso de abscesso cerebral actinomicótico é apresentado mostrando a necessidade de inclusão desta patologia no diagnóstico diferencial dos processos infecciosos que acometem o sistema nervoso central.Actinomycosis located in the central nervous system is an extremely uncommon event, but if correctly diagnosed and properly treated may have a good prognosis. This case report of a cerebral abscess caused by actinomyces suggests that such a rare event should be included in the differential diagnosis of infectious diseases that affect the central nervous system.

  3. Actinomicose laríngea: relato de caso Actinomycosis of the larynx: a case report

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    Marcelo Carneiro Menezes

    2006-08-01

    Full Text Available Relatamos um caso de actinomicose laríngea mimetizando neoplasia, com revisão da literatura a respeito dos aspectos clínicos, patológicos e de imagens. Utilizamos tomografia computadorizada, exame loco-regional, nasofibroscopia e estudo anatomopatológico. A importância do estudo se deve à raridade da enfermidade, localização atípica e particularmente ao diagnóstico diferencial com neoplasia de laringe. Não identificamos, na literatura, casos com avaliação por meio de tomografia computadorizada.We report a case of a patient with actinomycosis of the larynx mimicking a neoplasm. A literature review, clinical features, pathology and imaging findings is also presented. This paper reports a rare disease occurring in an atypical location, simulating larynx neoplasm. To our knowledge, there is no report of this disease and locations evaluated with computed tomography.

  4. A rare and an unusually delayed presentation of orbital actinomycosis following avulsion injury of the scalp

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    Hegde Vidya

    2010-01-01

    Full Text Available We report a rare case of orbital swelling presenting one year after head trauma. An initial fine needle aspiration cytology revealed it to be an infected organizing hematoma. However, broad-spectrum antibiotics did not resolve the infection and the orbital lesion continued to grow in size, as evaluated by magnetic resonance imaging. Incisional biopsies were done, which were reported as orbital actinomycosis. Patient has responded well to treatment with penicillin. This case is of interest due to the delayed presentation of an orbital complication of head trauma and the rare infection with actinomyces. It also highlights the importance of using appropriate antibiotics, as well as the need for long-term treatment.

  5. PELVIC ACTINOMYCOSIS MIMICKING A LOCALLY ADVANCED PELVIC MALIGNANCY--CASE REPORT.

    Science.gov (United States)

    Velenciuc, Natalia; Velenciuc, I; Makkai Popa, S; Roată, C; Ferariu, D; Luncă, S

    2016-01-01

    We present the case of a former user of an intrauterine contraceptive device (IUD) for 10 years, diagnosed with a bulky, fixed pelvic tumor involving the internal genital organs and the recto sigmoid, causing luminal narrowing of the rectum, interpreted as locally advanced pelvic malignancy, probably of genital origin. Intraoperatively, a high index of suspicion made us collect a sample from the fibrous wall of the tumor mass, large Actinomyces colonies were thus identified. Surgery consisted in debridement, removal of a small amount of pus and appendectomy, thus avoiding a mutilating and useless surgery. Specific antibiotic therapy was administered for 3 months, with favorable postoperative and long-term outcomes. Pelvic actinomycosis should always be considered in the differential diagnosis of pelvic tumors in women using an IUD. The association of long-term antibiotic treatment is essential to eradicate the infection and prevent relapses.

  6. Isolated Abdominal Wall Actinomycosis Associated with an Intrauterine Contraceptive Device: A Case Report and Review of the Relevant Literature

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    Sinan Carkman

    2010-01-01

    Full Text Available Isolated abdominal wall actinomycosis in the presence of an intrauterine contraceptive device (IUCD is extremely rare and only six such cases have been reported in the literature. We report a case where clinical and radiological examinations revealed a pseudotumor within the anterior abdominal wall. After being lost to follow-up, the patient presented two years later with the enlargement of the mass. The mass including the affected anterior abdominal wall was completely excised. The diagnosis of actinomycosis was established postoperatively by histopathological examination. Further questioning concerning her gynecological history revealed long-term use of the same IUCD. Surgical excision of the actinomycotic pseudotumour and removal of the IUCD followed by antibiotic therapy resulted in the full recovery of the patient.

  7. Primary hepatic actinomycosis mimicking hepatic malignancy with metastatic lymph nodes by F-18 FDG PET/CT

    Energy Technology Data Exchange (ETDEWEB)

    Kong, Eun Jung [Yeungnam Univ. Medical School and Hospital, Daegu (Korea, Republic of)

    2016-03-15

    Hepatic involvement is usually secondary to abdominal actinomycosis infection. Symptom onset is typically subscute and the disease follows a chronic and indolent course. These lesions are called inflammatory pseudotumors and cannot be differentiated from malignant tumors by radiological examination alone. Laboratory tests showed mild anemia; hemoglobin 119 g/L, elevated white blood cell count of 23,060/mm{sup 3}, AST 33 U/L, ALT 45 U/L, and γ-GT 155 U/L.

  8. Radiologic Findings of Oral Bisphosphonate-Related Osteonecrosis of the Maxilla, Complicated by Actinomycosis: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yi Kyung; Kim, Hyung Jin; Kim, Eun Hee; Chung, Seung Kyu; Hong, Jong Rak [Samsung Medical Center, Seoul (Korea, Republic of)

    2010-01-15

    Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a rare, but serious complication, which has recently been more frequently reported. However, this entity is unfamiliar to radiologists. We report a case of BRONJ complicated by actinomycosis following a tooth extraction in a 68-year-old woman who has been treated with oral bisphosphonate for treatment of osteoporosis over the last 3 years and 3 months

  9. Palatal Actinomycosis and Kaposi Sarcoma in an HIV-Infected Subject with Disseminated Mycobacterium avium-intracellulare Infection

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    Yuria Ablanedo-Terrazas

    2012-01-01

    Full Text Available Actinomyces and Mycobacterium avium-intracellulare are facultative intracellular organisms, members of the bacterial order actinomycetales. Although Actinomyces can behave as copathogen when anatomic barriers are compromised, its coinfection with Mycobacterium avium-intracellulare has not previously been reported. We present the first reported case of palatal actinomycosis co-infection with disseminated MAC, in an HIV-infected subject with Kaposi sarcoma and diabetes. We discuss the pathogenesis of the complex condition of this subject.

  10. [The course of actinomycosis of female reproductive organs mimicking ovarian cancer--the diagnostic limits and difficulties].

    Science.gov (United States)

    Milczek, Tomasz; Gołka, Karolina; Klasa-Mazurkiewicz, Dagmara; Emerich, Janusz

    2006-12-01

    A case of actinomycosis presenting as tubo-ovarian abscess, misdiagnosed as ovarian malignancy in 54-year old woman with IUD is reported. Author presents the diagnostic problems due to uncommon location, no reliable clinical manifestation and nonspecific CT imaging findings, based on current literature. Knowledge of the characteristic features may help one consider the possibility of actinomycetic infection in the differential diagnosis, in patients with a previous history of predisposing factors and treat them appropriately.

  11. Actinomicose pulmonar com envolvimento da parede torácica Lung actinomycosis with chest wall involvement

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    Marcelo Cunha Fatureto

    2007-02-01

    Full Text Available A Actinomicose é uma infecção rara, crônica, supurativa e granulomatosa que pode envolver diversos órgãos. A infecção pulmonar geralmente está relacionada à imunodepressão e à saúde bucal precária. O envolvimento torácico é incomum (10 - 20%, a parede torácica é acometida em apenas 12% destes casos. No presente trabalho, é descrito o caso de um paciente de 26 anos, não HIV e sem co-morbidades, assintomático respiratório, com massa infra-escapular, de crescimento progressivo, muito dolorosa, com sinais locais flogísticos, sem trauma local, apresentando febre persistente, com três meses de evolução. O diagnóstico inicial foi de neoplasia de partes moles de parede torácica. À biopsia incisional da referida massa, houve saída de secreção gelatinosa vinhosa com grânulos amarelados, sugestivos de actinomicose, sendo confirmado por exame anatomopatológico. Empiricamente foi instituída ciprofloxacina devido alergia à cefalosporina. Houve excelente resposta clínica à drenagem externa e à medicação prescrita. Não houve recaída da doença em 18 meses de seguimento.Actinomycosis is an uncommon suppurative granulomatous chronic infection that may involve several organs. Lung infection is usually related to immunodepression and poor oral hygiene. Cases of thoracic involvement are rare (10 - 20% and only 12% of such cases affect the chest wall. This report describes the case of a 26-year-old HIV-negative patient without comorbidities or respiratory complaints who presented a very painful, progressively growing infrascapular mass, with local phlogistic signs and no local trauma, and persistent fever. It had been progressing for three months. The initial diagnosis was neoplasia of chest wall soft tissue. However, incision biopsy in this mass produced a red wine-colored gelatinous secretion containing yellowish granules suggestive of actinomycosis, which was later confirmed by anatomopathological examination

  12. Pulmonary actinomycosis

    Science.gov (United States)

    ... Destruction of parts of the lungs Emphysema Meningitis Osteomyelitis (bone infection) When to Contact a Medical Professional ... More Brain abscess Dental care - adult Empyema Meningitis Osteomyelitis Pleural effusion Tooth abscess Review Date 3/13/ ...

  13. Actinomycosis, a rare and unsuspected cause of anal fistulous abscess: report of three cases and review of the literature.

    Science.gov (United States)

    Coremans, G; Margaritis, V; Van Poppel, H P; Christiaens, M R; Gruwez, J; Geboes, K; Wyndaele, J; Vanbeckevoort, D; Janssens, J

    2005-03-01

    Primary perianal actinomycosis is rare. Sporadic cases, with lesions varying in extent have been reported. The infection is caused by the bacterium Actinomyces, which often is a saprophyte. Male gender and diabetes are risk factors, but the exact pathogenic mechanism remains speculative. The diagnosis is a challenge and often delayed, with a protracted history of masses and sinuses extending into the gluteal and genital region. The treatment, a combination of surgery and antibiotics, is poorly standardized. We report three cases and compare their characteristics to those of published cases, found by a computerized literature search (1968-2002). The lesions, a simple fistula-in-ano or a mass, were diagnosed in an early stage in all three patients. The infection always spread into the scrotum. There were no risk factors other than gender, except in one patient. The diagnosis was suspected by the observation of draining sulfur granules and promptly confirmed by histology in the three cases. All patients healed with antibiotics in addition to simple surgical procedures. Treatment consisted of amoxicillin for two weeks in two cases and more extended antimicrobial treatment in the third. These findings are contrasting with the classic picture of perianal actinomycosis. It is concluded that perianal actinomycosis can occur in the absence of risk factors and that early diagnosis requires a high degree of suspicion. An infection with Actinomyces should be suspected in the presence of lesions containing watery purulent material with sulfur granules. The indication for extended antibiotherapy combined with sphincter damaging surgery may need to be revised in the presence of early detection.

  14. Pulmonary actinomycosis imitating lung cancer on {sup 18}F-FDG PERT/CT: A case report and literature review

    Energy Technology Data Exchange (ETDEWEB)

    Qiu, Lin; Lan, Lian Jun; Feng, Yue; Huang, Zhan Wen; Chen, Yue [The First Affiliated Hospital, Sichuan Medical University, Sichuan (China)

    2015-12-15

    Here we report a case of 41-year-old man with a soft tissue density mass at right upper lung and palpable abscesses at right upper backside and right wrist. {sup 18}F-fluorodeoxyglucose positron emission tomography/computed tomography demonstrated a 7.8 × 5.0 cm mass with soft-tissue density in the upper lobe of the right lung with high metabolic activity. The infiltrative mass extended to adjacent chest wall soft tissue. Final diagnosis of pulmonary actinomycosis with multiple abscesses was made. The patient responded well to antibiotics treatment.

  15. Prevalence of Trichomoniasis, Vaginal Candidiasis, Genital Herpes, Chlamydiasis, and Actinomycosis among Urban and Rural Women of Haryana, India

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    Brij Bala Arora

    2014-01-01

    Full Text Available Despite being curable reproductive tract infections (RTIs including sexually transmitted infections continue to be a major health problem in developing countries. The present study was undertaken to know the prevalence of trichomoniasis, vaginal candidiasis, genital herpes, chlamydiasis, and actinomycosis in rural and urban women of Haryana by using wet mount, PAP smear, and fluorescent microscopic examination. Patients suspected of suffering from bacterial vaginosis were given treatment and were not included in the study. RTIs were seen in 16.6% of urban and 28.7% of rural women. The highest prevalence seen was that of trichomoniasis in both rural (24.2% and urban (15.7% women, followed by candidiasis (4.2% in rural and 0.6% in urban women, genital herpes (0.3% in rural and 0.2% in urban women, and chlamydiasis (0.02% in rural and 0.05% in urban women. Pelvic actinomycosis was seen in 1.4% of rural and 0.06% of urban women using intrauterine contraceptive devices. Mixed infection of Trichomonas vaginalis with Candida spp. was seen in 6.3% of rural women only. It is desirable to have a baseline profile of the prevalence of various agents causing RTIs in a particular geographic area and population which will help in better syndromic management of the patients.

  16. Uterine perforation with Lippes loop intrauterine device-associated actinomycosis: a case report and review of the literature.

    Science.gov (United States)

    Phupong, V; Sueblinvong, T; Pruksananonda, K; Taneepanichskul, S; Triratanachat, S

    2000-05-01

    A case of a 67-year-old postmenopausal woman, gravida 2, para 2, with an uterine perforation from actinomycotic infection with Lippes loop IUD is reported. She had the Lippes loop IUD inserted for 35 years, and had never had any pelvic examination nor Papanicolaou smear. She presented with acute abdominal pain. The clinical picture mimicked peptic ulcer perforation. The woman underwent laparotomy and exudative fluid was discovered in the abdominal cavity with the tip of the Lippes loop IUD at one of the two small holes of the uterine fundus. Total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed. The postoperative microscopic pathological report demonstrated characteristics of actinomycosis. She was treated with parenteral high-dose penicillin for 4 weeks followed by oral penicillin for 6 months. The woman had an uneventful recovery. To our knowledge, this is the first case report of uterine perforation due to Lippes loop IUD-associated actinomycotic infection.

  17. Primary cutaneous actinomycosis of the foot simulating a soft tissue neoplasm: a case report; Actinomicose cutanea primaria do pe simulando neoplasia de partes moles: relato de caso

    Energy Technology Data Exchange (ETDEWEB)

    Vieira, Renata La Rocca; Meirelles, Gustavo de Souza Portes; Yamashita, Jane; Oliveira, Heverton Cesar de; Fernandes, Artur da Rocha Correa [Universidade Federal de Sao Paulo (UNIFESP), SP (Brazil). Escola Paulista de Medicina (EPM). Dept. de Diagnostico por Imagem; Turrini, Elizabete [Universidade Federal de Sao Paulo (UNIFESP), SP (Brazil). Escola Paulista de Medicina (EPM). Disciplina de Dermatologia]. E-mail: renatalarocca@bol.com.br

    2003-08-01

    We report a case of a patient with primary cutaneous actinomycosis of the foot simulating a soft tissue neoplasm. A literature review on the incidence, clinical features, pathology and imaging findings is also presented. The plain films and magnetic resonance imaging findings and the pathology results are presented. This paper reports a rare disease occurring in an atypical location, simulating a soft tissue neoplasm. (author)

  18. Radiographic findings in the thoracic actinomycosis: apropos a clinical case; Achados radiograficos na actinomicose pulmonar: a proposito de um caso clinico

    Energy Technology Data Exchange (ETDEWEB)

    Hochhegger, Bruno [Santa Casa de Misericordia de Porto Alegre, RS (Brazil)]. E-mail: brunorgs@pop.com.br; Haygert, Carlos Jesus Pereira; Antunes, Paulo Sergio Pase [Hospital Universitario de Santa Maria, RS (Brazil); Gazzoni, Fernando [Pontificia Universidade Catolica do Rio Grande do Sul (PUC-RS), Porto Alegre, RS (Brazil). Hospital Sao Lucas. Radiologia; Andrade, Rubes Gabriel Feijo [Instituto de Cardiologia - ISD, Porto Alegre, RS (Brazil). Radiologia; Orige, Samuel [Hospital das Clinicas de Porto Alegre, RS (Brazil). Cirurgia

    2007-01-15

    The chronic infection caused by Actinomyces bacteria can result in a suppurative inflammatory response with generation of granulomas. The most characteristic feature is the contiguous dissemination, without respect the anatomic lines and with fistulating process. The computed tomography shows a non-segmentary disease of air space and in magnetic resonance imaging can have its characteristic spread evaluated, generating low signal in T1 and high signal in T2. We have to consider actinomycosis in the differential diagnosis of granulomatous and neoplasic diseases, avoiding retard in treatment and its characteristic dissemination. (author)

  19. Actinomicosis cervicofacial tras cirugía ortognática: A propósito de un caso Cervicofacial actinomycosis after orthognathic surgery: a case report

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    Germán Macía

    2011-06-01

    Full Text Available Objetivos: Presentar un caso de actinomicosis cervicofacial tras cirugía ortognática. Material y métodos: Varón de 32 años, intervenido de cirugía ortognática bimaxilar en otro centro, que al cabo de varias semanas comienza a desarrollar una masa laterocervical derecha con signos de inflamación local intermitente. Las pruebas de imagen cervical informan de tumoración sólida o vascular. La citología refiere linfocitosis. Resultados: Al cabo de 2 años es intervenido y se le realiza una incisión tipo Risdon cervical, en la que se observa un granuloma caudal a la celda submaxilar derecha y una fístula con trayecto hasta el nivel del ángulo mandibular. El informe de anatomía patológica describe absceso con cambios crónicos y colonia de actinomices. Conclusiones: El diagnóstico temprano de actinomicosis cervicofacial es difícil y sólo un 10% se diagnostican en el inicio de su presentación. Aunque es un hecho infrecuente, debemos considerar la actinomicosis cervicofacial en pacientes intervenidos de cirugía ortognática que desarrollaron una masa cervical varias semanas después de la intervención.Objectives: Presentation of a case of cervicofacial actinomycosis after orthognathic surgery. Material and methods: A 32-year-old male underwent bimaxillary orthognathic surgery at another clinic. Several weeks after surgery, the patient developed a right lateral mass in the neck with intermittent signs of local inflammation. Cervical imaging suggested a solid or vascular tumor. The cytology revealed lymphocytosis. Results: Two years after the index intervention, surgery performed through a Risdontype cervical incision revealed a granuloma in the lower right submaxillary cell with a fistula to the mandibular angle. The pathology report was consistent with chronic abscess with actinomyces colonization. Conclusions: Early diagnosis of cervicofacial actinomycosis is difficult and only 10% of cases are detected at onset. Although uncommon

  20. Actinomicosis: presentación de un caso y revisión del tema con énfasis en los aspectos orales Actinomycosis in children with emphasis on oral aspects

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    Luis Fernando Gómez Jiménez

    1997-04-01

    Full Text Available En el presente artículo se actualizan los conocimientos sobre actinomicosis y se presenta el caso de un niño con la forma torácica de dicha entidad. La actinomicosis es una infección infrecuente que puede afectar cualquier parte del cuerpo; los Actinomyces son bacilos o filamentos gram positivos que forman parte de la flora endógena de las mucosas en especial las de las cavidades oral e intestinal. Su comportamiento es insidioso pero en oportunidades tiene expresión aguda, fistulización a piel y cicatrización con fibrosis. Los llamados gránulos de azufre son una característica macroscópica del exudado que contribuye al diagnóstico de laboratorio. La infección inicial para la forma cervicofacial suele provenir de la cavidad oral y extenderse a la vecindad o ser aspirada a los pulmones. El tratamiento de elección es la penicilina, inicialmente endovenosa y seguidamente oral por un lapso no menor de 6 meses. Algunas formas requieren manejo quirúrgico. We report the case of a child with thoracic actinomycosis and review this disease. Actinomycosis is a rare infection that can affect any part of the body; Actinomyces are gram positive bacilli or filaments belonging to the endogenous flora of the mUCOUS membranes, specially that of the oral cavity and the intestinal tract. Actinomycosis usually behaves as an insidioUS disease but may ocassionally have acute expressions with fistulization to the skin and fibroUS healing during resolution. The So called sulfur granules are an important macroscopic detail that helps establish the diagnosis. Actinomyces infections usually start in the oral cavity for the cervicofacial form and then spread to contiguous tissues or to the lungs via aspiration. Penicillin is the drug of choice and surgical drainage may become necessary.

  1. 2株嗜碱性放线菌的分离鉴定及特性研究%Isolation, identification and characterization of two basophilic actinomycosis

    Institute of Scientific and Technical Information of China (English)

    熊鹰; 余金辉; 阿不都克里木·热依木; 魏艳红; 李逸; 莫小妍; 陈湖星; 袁永泽; 刘德立

    2012-01-01

    从新疆巴洲和硕县碱性土壤中分离纯化出2株放线菌菌株XJ-1和XJ-4,对其形态特征、生理生化特性、抗生素产生以及16SrRNA基因序列分析等方面进行了多种特性研究.结果表明.2株放线菌在pH7.0的中性条件下不能生长,在pH12.0的强碱性条件下能够生长,最适生长pH为10.0,属于嗜碱性放线菌.2株放线菌菌株能耐受10%的NaCl,最高耐受温度为45℃.菌株XJ-1产生抗生素,能抑制柑橘绿霉菌、水稻轮纹菌、棉花枯萎菌和小麦赤霉菌的生长.16S rRNA基因同源性分析表明XJ-1属于拟诺卡氏菌属的Nocardiopsis dassonvillei,序列相似性达到了99.9%.而XJ-4与Nocardiopsis.sp.AF-333的序列相似性达到了99.3%,有可能是一新种.%Two actinomycete strains XJ-1 and XJ-4 were isolated from the alkaline soil of Shuo County and BaZhou County in Xinjiang Province. Based on the morphology, physiological and biochemical characteristics, antibiotics production and 16S rRNA gene sequence analysis, the results showed that the optimum growth pH of these two baso-philic actinomycosis was 10. 0; they could not grow in the neutral conditions of pH7. 0 and could grow in the strong alkaline conditions of pH12. 0. Two actinomycete strains had a tolerance of 10% NaCl and the highest tolerance of temperature were 45℃. XJ-1 was able to produce antibiotics. It could obviously inhibit the growth of Penicillium digi-tatum, but also inhibit the growth of Rhizoctonia solani, Fusariumoxysporum and Fu-sarium raminearum. XJ-1 was preliminarily determined to be the Nocardiopsis dassonvil-lei, their sequence similarity reached 99. 9%. The homology of the 16S rDNA sequences of strain XJ-4 with Nocardiopsis. sp. AF-333 was more than 99. 0% , so the strain XJ-4 maybe a new species belonged to the basophilic actinomycetes.

  2. Actinomycosis of the Chest X-ray Plain Film and CT Imaging Features%胸部放线菌病的X线平片和CT影像特点研究

    Institute of Scientific and Technical Information of China (English)

    岳莉; 闫国梁

    2015-01-01

    Objective Analysis actinomycosis of the chest X-ray plain film and CT tomography imaging characteristics, the evaluation of the value of X-ray and CT in the diagnosis of the disease.Methods Choose from January 2005 to February 2015, in our hospital during the period, confirmed by laboratory tests for patients with thoracic actinomycosis 10 cases as the research object, all patients were performed X-ray plain film and CT tomography; CT images with a standard algorithm, multi plane restructuring image, image characteristics.Results This group of 10 cases with X-ray is, lateral chest plain film are displayed as mass and large dense shadow, but did not show empty, liquefied gas and lesions; CT examination results showed that 52 actinomycetes lesions involving 18 normal; 8 cases of patients with CT images show that mass as the main lesions, lung see more spots or patch around the lesions and the funicular fuzzy shadow; Mass in the thin wall, and hollow, thin wall smooth, hollow with low density liquefaction and scattered suspended gas oven shadow; CT scan showed to see gas-liquid surface; CT images of 10 cases were showed lesion adjacent pleural thickening, 8 cases of patients with lung CT images showed the door increases and/or mediastinal lymph nodes, 2 cases of right lung CT images showed patchy shadow merge mediastinal abscess.Conclusion X-ray plain film to check the chest actinomycosis cannot view demonstrates the focal area of cavity, liquid and gas, limited diagnostic value and CT tomography can display the details of the lesion, has the characteristic, has high diagnostic value.%目的:分析胸部放线菌病的X线平片和CT体层摄影术影像特点,评价X线及CT在诊断该病中的价值。方法选择2005年1月至2015年2月期间我院收治,经实验室检查证实为胸部放线菌病的患者10例为研究对象,所有患者均行X线平片和CT体层摄影术检查;CT影像采用标准算法、多平面重组图像,观

  3. Medical image of the week: actinomycosis

    Directory of Open Access Journals (Sweden)

    Siddiqi TA

    2015-05-01

    Full Text Available No abstract available. Article truncated at 150 words. A 55-year-old man with history of tobacco and alcohol abuse, presented with unresolving pneumonia despite treatment with moxifloxacin. It was thought to be possible coccidioidomycosis and an azole was started. However, he returned with increasing dyspnea and hypoxemia. He had leukocytosis with a thoracic CT revealing a loculated empyema, multifocal necrotizing infection and a large intrapulmonary abscess (Figure 1. He was admitted to MICU, intubated and ventilated. He was in septic shock requiring fluid resuscitation, vasopressors, and broad antibiotics. Bronchoscopy revealed erythematous and edematous airways, with drainage of over one liter of purulent fluid. A chest tube was placed to drain pleural fluid with removal of around two liters of blood-tinged, purulent fluid. His condition worsened with development of disseminated intravascular coagulation leading to hemorrhagic shock. He arrested and died. Gram stain on bronchoalveolar lavage fluid showed mixed gram negative and gram variable rods, and cultures grew lactobacillus species. GMS ...

  4. Female pelvic actinomycosis and intrauterine contraceptive devices

    OpenAIRE

    2010-01-01

    Faustino R Pérez-López1,2, José J Tobajas1,3, Peter Chedraui41Department of Obstetrics and Gynecology, Facultad de Medicina, Universidad de Zaragoza; 2Hospital Clínico Lozano Blesa; 3Hospital Universitario Miguel Servet, Zaragoza, Spain; 4Enrique C. Sotomayor Obstetrics and Gynecology Hospital, Guayaquil, EcuadorAbstract: Female genital Actinomyces infection is relatively rare, although strongly related to long-lasting intrauterine contraceptive dev...

  5. Management of Intrauterine Device-Associated Actinomycosis

    OpenAIRE

    1993-01-01

    Objective: To assess various methods of management of actinomyces-like organisms associated with intrauterine devices. Methods: A retrospective chart review of 173 patients with intrauterine device-associated actinomyces- like organisms detected on Pap smear was performed. The patients were managed by IUD removal with or without antibiotic therapy, antibiotic therapy alone, or no treatment at all. Results: The success rate as reflected in negative follow-up smear was 100% for IUD removal comb...

  6. Management of Intrauterine Device-Associated Actinomycosis

    Science.gov (United States)

    Amin-Hanjani, Soheil

    1993-01-01

    Objective: To assess various methods of management of actinomyces-like organisms associated with intrauterine devices. Methods: A retrospective chart review of 173 patients with intrauterine device-associated actinomyces- like organisms detected on Pap smear was performed. The patients were managed by IUD removal with or without antibiotic therapy, antibiotic therapy alone, or no treatment at all. Results: The success rate as reflected in negative follow-up smear was 100% for IUD removal combined with antibiotics, 97.4% for IUD removal alone, and 36.8% for antibiotics therapy alone. Conclusions: The best way to manage intrauterine device-associated actinomyces-like organisms is removal of the device with or without antibiotics. PMID:18475332

  7. Intracranial actinomycosis: Varied clinical and radiologic presentations in two cases

    Directory of Open Access Journals (Sweden)

    Sandeep Mohindra

    2012-01-01

    Full Text Available Two patients with primary actinomycotic brain infection are presented here. The first case had 2 predisposing factors, cardiac septal defect and chronic mastoiditis, whereas the second patient was a chronic smoker, belonging to a desert region. Both the patients were successfully managed with surgical debridement and prolonged administration of antibiotics.

  8. [Pulmonary actinomycosis and tuberculosis. A comorbidity pediatric case].

    Science.gov (United States)

    Bisero, Elsa D; Luque, Graciela F; Rizzo, Cristina N; Zapata, Alejandra E; Cuello, María S

    2016-08-01

    La actinomicosis es una infección supurativa crónica, producida por bacterias Gram-positivas anaeróbicas o especies Actinomyces microaerófilas. Es rara en niños y adolescentes; es más común en inmunodeprimidos. El Mycobacterium tuberculosis colabora en el desarrollo de la enfermedad. La afectación pulmonar aparece como un cuadro de condensación crónica que no mejora con el tratamiento antibiótico convencional. Las complicaciones clásicas de afectación de la pared torácica con fistulización y supuración en «granulo de azufre» son descritas con menor frecuencia en la actualidad. El diagnóstico es un verdadero desafío y se establece mediante el aislamiento de las especies de Actinomyces. El tratamiento de elección para todas las formas clínicas de la enfermedad es el uso prolongado de antibióticos. Objetivo. Presentar un caso pediátrico de comorbilidad entre tuberculosis y actinomicosis. Resaltar la importancia de la sospecha diagnóstica de actinomicosis frente a todo proceso supurado crónico.

  9. Actinomycosis: etiology, clinical features, diagnosis, treatment, and management

    OpenAIRE

    Valour F; Sénéchal A; Dupieux C; Karsenty J; Lustig S; Breton P; Gleizal A; Boussel L; Laurent F; Braun E; Chidiac C; Ader F; Ferry T

    2014-01-01

    Florent Valour,1–3 Agathe Sénéchal,1,2 Céline Dupieux,2–4 Judith Karsenty,1,2 Sébastien Lustig,2,5 Pierre Breton,2,6 Arnaud Gleizal,2,7 Loïc Boussel,2,8,9 Frédéric Laurent,2–4 Evelyne Braun,1 Christian Chidiac,1–3 Florence Ader,1–3 Tristan Ferry1–3 1Service des Maladies Infectieuses et Tropicales, Hospices Civils de Lyon, Groupement Hospitalier Nord, Lyon, Fra...

  10. [Pelvic actinomycosis in IUD wearers. A case report].

    Science.gov (United States)

    Di Capua, F

    1994-01-01

    The author describes a case of pelvic actinomyces in woman using intrauterine contraceptive device, in support of frequent association on two conditions. The woman was treated by surgery. Moreover, the author underlines the difficulty in diagnosis, which explains the frequent recourse to surgery.

  11. Pelvic actinomycosis and usage of intrauterine contraceptive devices.

    Science.gov (United States)

    Kelly, J; Aaron, J

    1982-01-01

    Pelvic inflammatory disease (PID) is one of the most commonly encountered serious infectious disease entities in gynecology. The past decade has witnessed many advances in our understanding of the pathogenesis of PID. It is now evident that such pelvic infections are largely polymicrobial in origin, with major involvement by anaerobic organisms. Salpingo-oophoritis is a part of the spectrum of PID. Included among this group of infections are tubo-ovarian abscesses, traditionally referred to as either gonococcal or non-gonococcal in origin. Within the latter group of infections the importance of anaerobic organisms has also been elucidated. Of particular interest is the reported observation of an increased frequency of salpingo-oophoritis among users of intrauterine devices (IUDs). These reports have noted the specific occurrence of serious pelvic infections due to Actinomyces species, and this will be the topic of the infectious disease conference. Our patient presented with a chronic illness characterized by lethargy, back pain, fever, and anemia; subsequently evaluation disclosed the presence of a large pelvic mass which was confirmed as a tubo-ovarian abscess at surgery. Histological evaluation demonstrated involvement by Actinomyces species. This patient's illness is discussed as a complication of chronic IUD usage with reference to specific management for this emerging problem.

  12. Abdominal and endometrial actinomycosis associated with an intrauterine device.

    Science.gov (United States)

    O'Brien, P. K.

    1975-01-01

    Actinomycotic endometrial infection associated with an intrauterine device (IUD) complicated chronic abdominal inflammatory disease in a 28-year-old woman. Colonies of organisms with morphologic resemblance to and staining reactions of Actinomyces israelii were observed in tissue adherent to the IUD and in inflamed omental and pericolic tissues. However, the organism could not be cultured. Because intact tissues are resistant to actinomyces it is likely that the IUD created an environment favouring the establishment and growth of the organism. Images FIG. 1 FIG. 2 PMID:1116090

  13. Preoperative diagnosis of pelvic actinomycosis by clinical cytology

    OpenAIRE

    2012-01-01

    Katsuya Matsuda,1 Hisayoshi Nakajima,2 Khaleque N Khan,1 Terumi Tanigawa,1 Daisuke Hamaguchi,1 Michio Kitajima,1 Koichi Hiraki,1 Shingo Moriyama,3 Hideaki Masuzaki11Department of Obstetrics and Gynecology, Nagasaki University Graduate School of Biomedical Sciences, 2Department of Health Sciences, Nagasaki University Graduate School of Biomedical Sciences, 3Shimabara Maternity Clinic, Nagasaki, JapanBackground: The purpose of this work was to investigate whether clinical cytology could be usef...

  14. Actinomicose pulmonar com envolvimento da parede torácica Lung actinomycosis with chest wall involvement

    OpenAIRE

    Marcelo Cunha Fatureto; Paulo Fernando Oliveira; Almeida,Cynthia Ottaiano R.; Fernandes,Lúcia Helena G.

    2007-01-01

    A Actinomicose é uma infecção rara, crônica, supurativa e granulomatosa que pode envolver diversos órgãos. A infecção pulmonar geralmente está relacionada à imunodepressão e à saúde bucal precária. O envolvimento torácico é incomum (10 - 20%), a parede torácica é acometida em apenas 12% destes casos. No presente trabalho, é descrito o caso de um paciente de 26 anos, não HIV e sem co-morbidades, assintomático respiratório, com massa infra-escapular, de crescimento progressivo, muito dolorosa, ...

  15. [Actinomycosis sub-masseter abscess, simulating a parotiditis. Review of case and revision of literature].

    Science.gov (United States)

    Padilla Parrado, M; Aranzana Gómez, A; Jiménez Antolín, J A; García Manríquez, A; Céspedes Más, M; Menéndez Loras, L M

    2003-01-01

    We present one case of a pluripathologic female patient who has developed an submaseterin abscess secondary to an actinomyces mandibular osteomielitis. The initial presentation seems an acute supurative parothiditis. We describe its presentation, evolution, special tests done for its diagnostic, as also the discussion of the type and duration of the treatment. And we include also a differential diagnosis between the two diseases, with a similar form. We do also a bibliographic revision of the few similar cases published.

  16. [Reactive and areactive actinomycosis infection of the female genitals and differentiation of pseudoactinomycosis].

    Science.gov (United States)

    Horn, L C; Bilek, K

    1995-01-01

    Actinomycotic infections of the female genital tract are rare. In relation of clinical symptoms and therapeutical implications, reactive and non-reactive infections can be distinguished. During a period of seven years we observed five reactive infections. All these cases with tubo-ovarian abscesses (TOA) were seen in women using intrauterine devices (IUD) for 9.8 years on average. 9.1% of all TOA in this period were caused by actinomyces. Ten cases showed a non-reactive infection (colonisation). The frequency was 1.9%. In three cases pseudosulfurgranules (pseudoactinomycotic granules) were identified histologically by PAS-, Grocott-and Kossa-staining). One case showed a bacterial infection of a mucinous cystadenofibroma of the ovary with colonization of microorganisms similar to cases of botryomycosis in lung and other organs. Reactive infections require antibiotic therapy. Reimplantation of IUD should be done after 4 to 8 weeks, even in areactive infections. In specimens with pseudosulfurgranules no therapy is necessary.

  17. [Unavoidable surgical intervention in two women with severe actinomycosis during IUD use].

    Science.gov (United States)

    Bergenhenegouwen, L A; de Haan, H H; Sijbrandij, E S; Groeneveld, P H

    2003-11-29

    Extensive abdominal infections with Actinomyces were diagnosed in two women aged 35 and 33 years respectively, who suffered from the nonspecific symptoms fever and abdominal pain. These infections occur more often in women with an intrauterine device. Development of an abdominal mass with ureter or bowel obstruction may cause hydronephrosis and mechanical ileus. The patients underwent a laparotomy and a double-J catheter was inserted, which could be removed later on (temporary stoma). Treatment included high-dose penicillin i.v. followed by oral amoxicillin. Both patients recovered. It may be difficult to establish this diagnosis: the first patient was diagnosed by histopathological examination, in the second Actinomyces had been found in a routine cervical smear a few years earlier.

  18. Chest wall actinomycosis in association with the use of an intra-uterine device.

    Science.gov (United States)

    McBride, W J; Hill, D R; Gordon, D L

    1995-02-01

    A 31 year old woman presented with a chest wall abscess due to Actinomyces israellii and Porphyromonas asaccharolytica (previously Bacteroides asaccharolyticus). She was a long-term user of an intra-uterine device (IUD) and, although asymptomatic, had radiological evidence of pelvic infection. Actinomyces-like organisms were seen on cervico-vaginal smears. The abscess was surgically drained, the IUD removed, and a prolonged course of amoxycillin/clavulanic acid given.

  19. Retroperitoneal fibrosis and obstructive uropathy due to actinomycosis: case report of a treatment approach.

    Science.gov (United States)

    Yagmurdur, Mahmut Can; Akbulut, Sami; Colak, Aysel; Aygun, Cem; Haberal, Mehmet

    2009-01-01

    An actinomycotic retroperitoneal infection usually occurs in the presence of an intrauterine device (IUD). It can result in pelvic inflammatory disease and diffuse retroperitoneal fibrosis. A 39-year-old patient was admitted to the emergency unit with left flank pain. A computed tomography scan of the abdomen showed bilateral hydroureteronephrosis and a retroperitoneal malignant mass. Other tumors were excluded with a colonoscopy and an upper gastrointestinal endoscopy. Results of a fine needle aspiration biopsy showed fibrosis compatible with retroperitoneal mesenteritis. Double-J stents were placed in both ureters, and immunosuppressive therapy was started. The patient had clinical and radiologic responses to the therapy. A bilateral ureterolysis and sigmoid colon resection were done. The pathology report showed fibrosis and Actinomyces israelii infection. Parenteral and oral penicillins were administered. The probability of an Actinomyces infection in patients with retroperitoneal fibrosis should be kept in mind, especially in cases in which the patient has an intrauterine device.

  20. Abdominopelvic actinomycosis in three different locations with invasion of the abdominal wall and ureteric obstruction: An uncommon presentation

    Directory of Open Access Journals (Sweden)

    Christian L. Galata

    2015-01-01

    Conclusion: A rare actinomyceal infection should be considered in patients with a non-specific pelvic mass and atypical abdominal presentations, especially if a previous history of IUD usage is known.

  1. Thoracic Actinomycosis Simulating Neoplastic Disease In Pediatrics [actinomicose Torácica Simulando Doença Neoplásica Em Pediatria

    OpenAIRE

    Ricardo Mendes Pereira; Fabio Bucaretchi; Antonia Teresinha Tresoldi

    2012-01-01

    OBJETIVO: Descrever um caso de actinomicose pulmonar em paciente pediátrico. DESCRIÇÃO DO CASO: Menina de dez anos, saudável, com história de dor torácica há três meses, evoluindo há dois meses com abaulamento em parede torácica anterior esquerda. Ao exame físico, apresentava massa de 8,0cm de diâmetro em região inframamilar esquerda, sem sinais flogísticos. A tomografia do tórax mostrou processo expansivo em parede torácica anterior esquerda. Realizou-se biópsia e a cultura do material ident...

  2. Large Bowel Obstruction in a Young Woman Simulating a Malignant Neoplasm: A Case Report of Actinomyces Infection

    Science.gov (United States)

    Nissi, R.; Blanco Sequeiros, R. B.; Lappi-Blanco, E.; Karjula, H.; Talvensaari-Mattila, A.

    2013-01-01

    Pelvic and intra-abdominal Actinomycosis can be difficult to diagnose preoperatively and it may also mimic many other diseases, including malignancies. We present a patient with pelvic Actinomycosis probably caused by a long-standing intrauterine device (IUD). We emphasize the challenges in diagnostic process and stress that though a rare disease, intra-abdominal Actinomycosis should be suspected in cases with intra-abdominal mass of uncertain etiology. The early recognition may spare the patient from extensive surgical operation. PMID:23936699

  3. Large Bowel Obstruction in a Young Woman Simulating a Malignant Neoplasm: A Case Report of Actinomyces Infection

    OpenAIRE

    2013-01-01

    Pelvic and intra-abdominal Actinomycosis can be difficult to diagnose preoperatively and it may also mimic many other diseases, including malignancies. We present a patient with pelvic Actinomycosis probably caused by a long-standing intrauterine device (IUD). We emphasize the challenges in diagnostic process and stress that though a rare disease, intra-abdominal Actinomycosis should be suspected in cases with intra-abdominal mass of uncertain etiology. The early recognition may spare the pat...

  4. Large bowel obstruction in a young woman simulating a malignant neoplasm: a case report of actinomyces infection.

    Science.gov (United States)

    Nissi, R; Blanco Sequeiros, R B; Lappi-Blanco, E; Karjula, H; Talvensaari-Mattila, A

    2013-01-01

    Pelvic and intra-abdominal Actinomycosis can be difficult to diagnose preoperatively and it may also mimic many other diseases, including malignancies. We present a patient with pelvic Actinomycosis probably caused by a long-standing intrauterine device (IUD). We emphasize the challenges in diagnostic process and stress that though a rare disease, intra-abdominal Actinomycosis should be suspected in cases with intra-abdominal mass of uncertain etiology. The early recognition may spare the patient from extensive surgical operation.

  5. 9 CFR 71.4 - Maintenance of certain facilities and premises in a sanitary condition required; cleaning and...

    Science.gov (United States)

    2010-01-01

    ... contagious, infectious, or communicable disease of livestock or poultry other than slight unopened cases of actinomycosis or actinobacillosis (or both), bovine foot rot, atrophic rhinitis, ram epididymitis,...

  6. Perianal abscess caused by Actinomyces: report of a case.

    Science.gov (United States)

    Magdeburg, R; Grobholz, R; Dornschneider, G; Post, S; Bussen, D

    2008-12-01

    Most anal abscesses are caused by anal fistula and invasion of the surrounding tissues by a mixed colonic flora. The treatment comprises excision of the abscess and. if appropriate, fistulectomy. Primary anorectal actinomycosis and perianal actinomycosis are very rare and are caused by Actinomyces, which is a ubiquitous microaerophilic bacterium. Here we report a case of perianal actinomycosis. The patient had a short history of painless perineal induration without fever or leucocytosis with normal routine blood tests. After excision sulphur granules drained from the cavity and the pathological investigations were indicative of perianal actinomycosis. Appropriate surgery and antibiotic treatment healed the perianal infection. After elimination of other diagnoses, e.g. Crohn's disease, tuberculosis and malignant growths, this rare case of perianal actinomycosis should be kept in mind in the differential diagnosis of a painless perianal mass.

  7. Actinomicosis: presentación de un caso y revisión del tema con énfasis en los aspectos orales Actinomycosis in children with emphasis on oral aspects

    OpenAIRE

    Luis Fernando Gómez Jiménez; Dianelisa De La Hoz Rodríguez; Patricia Rivas Pulido; Miguel Builes; Juan Manuel Alfaro Velásquez

    1997-01-01

    En el presente artículo se actualizan los conocimientos sobre actinomicosis y se presenta el caso de un niño con la forma torácica de dicha entidad. La actinomicosis es una infección infrecuente que puede afectar cualquier parte del cuerpo; los Actinomyces son bacilos o filamentos gram positivos que forman parte de la flora endógena de las mucosas en especial las de las cavidades oral e intestinal. Su comportamiento es insidioso pero en oportunidades tiene expresión aguda, fistulización a pie...

  8. Optimization of Fermentation Conditions of Ferulic Acid Release from Brewers' Spent Grain by Actinomycosis%放线菌降解麦糟释放阿魏酸的发酵培养条件优化

    Institute of Scientific and Technical Information of China (English)

    程珊影; 李夏兰; 陈志燕; 方柏山

    2010-01-01

    应用均匀设计法设计和二次多项式逐步回归分析,对一株放线菌降解麦糟释放反式阿魏酸的发酵培养条件进行优化.由实验得出最优发酵培养条件:发酵时间为120 h,温度为28 ℃,摇瓶转速为220 r·min~(-1),装液量为30 mL,接种量为1 mL,初始pH值为8.0.然后,优化发酵培养基的碳源和氮源配方:麦糟质量浓度为120 g·L~(-1),麦糟粒径为0.054 mm.在此基础上,反式阿魏酸的最高释放率为25.38%,比发酵培养工艺优化前提高152.0%,而重要的是,放线菌利用麦糟释放阿魏酸的发酵培养基中不需要另外加入酵母粉.

  9. Large Bowel Obstruction in a Young Woman Simulating a Malignant Neoplasm: A Case Report of Actinomyces Infection

    Directory of Open Access Journals (Sweden)

    R. Nissi

    2013-01-01

    Full Text Available Pelvic and intra-abdominal Actinomycosis can be difficult to diagnose preoperatively and it may also mimic many other diseases, including malignancies. We present a patient with pelvic Actinomycosis probably caused by a long-standing intrauterine device (IUD. We emphasize the challenges in diagnostic process and stress that though a rare disease, intra-abdominal Actinomycosis should be suspected in cases with intra-abdominal mass of uncertain etiology. The early recognition may spare the patient from extensive surgical operation.

  10. [How is agonizing leg pain associated with an intrauterine device?].

    Science.gov (United States)

    Jäckel, Kristian; Braschler, Thomas; Jochum, Wolfram; Hülder, Tanja; Knechtle, Beat

    2015-05-06

    We report on a typical clinical course of pelvic actinomycosis: initial uncharacteristic discomfort develops into a systemic illness associated with a pelvic mass, which progresses so fast that along with the systemic infection further symptoms can be reduced to its growth rate--tiredness, abdominal pain, micturition deficiency, and leg pain. Distinction between malignancy and pelvic actinomycosis could be made only intraoperative. After hysterectomy and with antibiotics the patient recovered quickly.

  11. Actinomyces and Nocardia infections in chronic granulomatous disease

    Directory of Open Access Journals (Sweden)

    Shahindokht Bassiri-Jahromi

    2011-01-01

    Full Text Available Objective : Chronic granulomatous disease (CGD is an inherited disorder of the Nicotinamide adenine dinucleotide phosphate reduced oxidase complex characterized by recurrent bacterial and fungal infections. Disseminated infection by combination of opportunistic agents is being increasingly reported in CGD patients. We presented in the retrospective review of medical records, the etiology, presentation, clinical characteristics the infections detected, predisposing condition and outcome of nocardiosis and actinomycosis involved in a group of pediatric patients diagnosed with CGD. Materials and Methods: The clinical presentation of CGD-related infections was reviewed retrospectively from the medical records of all 12 patients with CGD. We studied respectively 12 patients between 2001 and 2008, and we analyzed two pediatric patients with CGD who acquired Nocardia and Actinomyces infections, and their clinical and microbiological characteristics were described. The material for investigations was collected from scrapings, crusts, pus from subcutaneous abscesses or exudation from sinus tracts, surgical debridement, and biopsy specimens. The microbiological diagnosis was determined by biochemical tests, histology, microscopy, and culture of clinical samples. Results: The medical records of 12 diagnosed CGD patients with suspected nocardiosis or actinomycosis were reviewed. One patient was diagnosed with actinomycosis and one patient with nocardiosis. Patients consisted of seven males and five females with ranging ages of 3 to 18 years. Nocardiosis and actinomycosis isolated in the two patients were confirmed by histology and culture methods. Neutrophil oxidative burst were absent (NBT=0 in both patients. The most common manifestations of CGD due to fungal infections, actinomycosis, and nocardiosis were osteomyelitis (42.8%, pulmonary infections (28.6%, lymphadenopathy (14.3%, and skin involvement (14.3% during their illness. Conclusion: Nocardiosis

  12. Actinomyces israelii in the genital tract of women with and without intra-uterine contraceptive devices.

    Science.gov (United States)

    Persson, E; Holmberg, K; Dahlgren, S; Nilsson, L

    1983-01-01

    Actinomycosis involving the female genital tract is more common among IUD users than others. The diagnosis is difficult and often delayed. It has been suggested that the finding of Actinomyces-like organisms or A. israelii in cervical smears indicates a risk of developing actinomycosis. A. israelii has not been regarded as a part of the indigenous genital flora. A group of IUD users without symptoms of genital tract infections were compared with a control group without IUDs. No Actinomyces-like organisms were found on cytological examination of cervical smears. Immunofluorescent staining and cultures identified A. israelii in 4% of the IUD users and in 3% of the non-users. Serologic precipitin tests for actinomycosis were negative in all women. None developed actinomycosis on follow-up of positive cases. The study indicates that A. israelii is a commensal of the female genital tract. The identification of A. israelii alone does not indicate that the patient risks developing actinomycosis. Other methods such as a serology test should be useful in defining the clinical significance of the findings.

  13. [Actinomyces and other bacteria isolated from cervical cultures of women using IUDs].

    Science.gov (United States)

    Güleç, N; Günalp, A

    1987-07-01

    In this study we performed endocervical cultures from 517 patients with infection. In 75 of these 517 cultures (14.5%) Actinomyces has been grown. The incidence of Actinomyces has increased in correlation with IUD period, but the type of IUD has not affected the incidence of Actinomyces. Actinomycosis of uterus is usually superficial. It rarely spreads and causes pelvic actinomycosis. Even it can change to systemic infection. For this reason, in women who have used IUDs for long period Actinomyces infection should be kept in mind. Clinicians should be in corporation with the laboratories, this is important for identification of the microorganism and for the right therapy.

  14. Unexpected cause of malignant otitis externa: A rare case report

    Directory of Open Access Journals (Sweden)

    Abdulla Al-otaibi

    2011-01-01

    Full Text Available Malignant otitis externa is an uncommon infection affecting the ear canal and temporal bone. The most common causative organism is Pseudomonas aeruginosa. In this article, we report a malignant otitis externa caused by actinomycosis, a case never been reported before in the literature.

  15. [Two women with a chronic process in the lower abdomen].

    Science.gov (United States)

    van de Lande, J; Spanjaard, L; Burger, M P

    2003-11-29

    Two women, aged 50 and 45 years, had a chronic process in the lower abdomen. The first presented with cough and progressive dyspnoea, and her chest X-ray raised the suspicion of a metastasis of a malignancy. The second patient had abdominal pain, frequent urination and irregular vaginal bleeding. She was initially treated for a urinary-tract infection. Diagnostic investigations showed pelvic actinomycosis in both patients. Both had used an intrauterine device (IUD). In the first patient a pelvic abscess was drained. Antimicrobial treatment consisted of penicillin i.v. for several weeks and orally for 6 months. Actinomycosis is a slowly progressive bacterial infection that characteristically expands through anatomic structures and can lead to fistulae and abscesses. The disease is caused by Actinomyces species. Diagnosis is often delayed because other diseases (e.g. malignancy) are considered more probable. Actinomycosis is associated with prolonged use of an IUD, but it is rare and removal of the IUD is not indicated unless symptoms of pelvic inflammatory disease are present. The mainstay of actinomycosis therapy is administration of an effective antibiotic (e.g. penicillin). Except for drainage of abscesses, surgical intervention is rarely necessary. When antimicrobial therapy is continued for 6-9 months, prognosis is favourable, as was the case in both patients.

  16. Pilonidal Sinus of the Glans Penis Associated with Actinomyces Case Reports and Review of Literature

    Directory of Open Access Journals (Sweden)

    Shylashree Chikkamuniyappa

    2004-01-01

    Full Text Available Pilonidal sinus is a well-recognized condition that occurs most commonly in the sacrococcygeal area of younger men. It is hypothesized to be an acquired chronic inflammation condition due mainly to hair trapped beneath the surface. A pilonidal sinus in the sacrococcygeal region is associated with recurrent infection, abscess formation, cellulitis, fistulae, and rarely, squamous cell carcinoma. A pilonidal sinus of the penis is a rare entity. The association of a penile pilonidal cyst and Actinomyces is even more uncommon with only three cases reported previously. Two cases of pilonidal sinus are reported in this paper. One of the cases was associated with actinomycosis. Pilonidal sinus of the penis should be considered in the clinical and pathological differential diagnosis and has to be distinguished from balanoposthitis, epidermal cyst, and carcinoma. The knowledge about possible association with actinomycosis is important to ensure early treatment.

  17. IUDs and colonization or infection with Actinomyces.

    Science.gov (United States)

    Westhoff, Carolyn

    2007-06-01

    Pelvic actinomycosis is an extremely rare disease that can occur in women with a long duration of intrauterine device (IUD) use. This type of abscess is usually unsuspected and, thus, diagnosed and treated surgically; however, long-duration treatment with penicillin can be completely effective. While the occurrence of actinomycosis is well documented by case reports, it is not possible to quantify the risk during IUD use. Approximately 7% of women using an IUD may have a finding of Actinomyces-like organisms on a Pap test. The prognostic significance of this finding is minimal because of the lack of sensitivity and specificity and a low positive predictive value. In the absence of symptoms, women with Actinomyces-like organisms on a Pap test do not need antimicrobial treatment or IUD removal.

  18. Empyema Secondary to Actinomyces meyeri Treated Successfully with Ceftriaxone Followed by Doxycycline

    Science.gov (United States)

    Piscopo, Tonio; Cassar, Karen

    2016-01-01

    Actinomycosis is a relatively rare infection caused by Gram-positive bacteria. We present the case of a 54-year-old, previously healthy, male patient with a history of severe penicillin allergy who developed severe pneumonia and empyema caused by Actinomyces meyeri. Presenting symptoms included productive cough, right upper quadrant pain, and chills and rigors. He required drainage of the empyema via tube and prolonged antibiotic treatment with intravenous ceftriaxone for 2 weeks followed by oral doxycycline for 6 months. PMID:27752374

  19. Actinomycosic tubo-ovarian abscess: dynamic CT findings; Tubo-ovarite actinomycosique. Apport de l`angioscanner pelvien

    Energy Technology Data Exchange (ETDEWEB)

    Bazot, M.; Boudghene, F.; Bigot, J.M. [Hopital Tenon, 75 - Paris (France); Davenne, C.; Benzakine, Y. [Hopital Robert-Debre, 75 - Paris (France)

    1997-07-01

    Pelvic actinomycosis is uncommon and usually responsible for tubo-ovarian abscesses which are similar in aspect with non-actinomycotic abscesses. They are usually a complication of an intra-uterine device (IUD) that can be absent as in this case. The differential diagnosis is ovarian cancer. The role of the dynamic CT scan for differential diagnosis in this case is presented. Preoperative diagnosis in this affection is important because of the excellent response to Penicillin. (author)

  20. Ultrasound-guided Transvaginal Aspiration in the Management of Actinomyces Pelvic Abscess

    OpenAIRE

    1996-01-01

    Background: Increasing reports of intrauterine device (IUD)-related abdominopelvic actinomycosis have been described recently. Surgical therapy has been the usual treatment when tubo-ovarian abscess is identified. Case: A 38-year-old woman suffering from Actinomyces pelvic abscess unresponsive to medical treatment underwent transvaginal ultrasound-guided needle aspiration. It resulted in marked improvement and avoided surgical treatment. Conclusion: Transvaginal needle aspiration of Actinomyc...

  1. Mandibular Actinomyces osteomyelitis complicating florid cemento-osseous dysplasia: case report

    Directory of Open Access Journals (Sweden)

    Edwards Sean P

    2011-07-01

    Full Text Available Abstract Background Apart from neoplastic processes, chronic disfiguring and destructive diseases of the mandible are uncommon. Case Presentation We report, perhaps for the first time, the simultaneous occurrence of two such conditions in one patient, in a case that emphasizes the importance of bone biopsy in establishing the correct diagnosis. Florid cemento-osseous dysplasia (FCOD is a chronic, disfiguring condition of the maxillofacial region. This relatively benign disease is primarily observed in middle-aged women of African ancestry. Cervicofacial actinomycosis is an uncommon and progressive infection caused by bacilli of the Actinomyces genus that typically involves intraoral soft tissues but may also involve bone. The accurate diagnosis of actinomycosis is critical for successful treatment. A diagnosis of osteomyelitis caused by Actinomyces bacteria was diagnosed by bone biopsy in a 53 year-old African-American woman with a longstanding history of FCOD after she presented with a new draining ulcer overlying the mandible. Conclusions Clinicians should be aware of the possibility of actinomycosis arising in the setting of FCOD, and the importance of bone biopsy and cultures in arriving at a definitive and timely diagnosis.

  2. Tuberculosis of Calcaneum: A Rare Case Report

    Directory of Open Access Journals (Sweden)

    Bhat Sandhya K

    2012-08-01

    Full Text Available Tuberculosis is a leading cause of morbidity and mortality in developing countries including India. Skeletal tuberculosis accounts for 1-3%. Tuberculosis of bone may evade the diagnosis for a long time, as it usually remains silent till either involvement of a neighbouring joint or development of a soft tissue swelling due to cold abscess formation. Tuberculosis of bone mimics clinical conditions like Chronic Osteomyelitis, Madura mycosis and Actinomycosis. There have been few case reports of unusual sites being affected and with unusual presentation by this disease.

  3. Microbiology in endodontics: an online study guide.

    Science.gov (United States)

    2008-05-01

    The Editorial Board of the Journal of Endodontics has developed a literature-based study guide of topical areas related to endodontics. This study guide is intended to give the reader a focused review of the essential endodontic literature and does not cite all possible articles related to each topic. Although citing all articles would be comprehensive, it would defeat the idea of a study guide. This section will present the topical areas of microorganisms involved in primary infection; microorganisms involved with failing endodontics, culturing, bacteremia, and endodontics; leaving teeth open; antibiotics; actinomycosis; sterilization of instruments and sterilization of gutta-percha, microorganisms in periradicular lesions; biofilms; and fungi, viruses, and prions.

  4. Super Infection of An Ovarian Dermoid Cyst with Actinomyces in An Infertile Woman

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    Saghar Salehpour

    2013-01-01

    Full Text Available We present super infection of an ovarian dermoid cyst with actinomyces in an infertile patient.This is a case-report study for evaluation a couple with male factor infertility, who was a goodcandidate for intracytoplasmic sperm injection (ICSI, while a 10 cm dermoid cyst was foundin the woman’s right ovary. Patient complained of pelvic pain, intermittent fever, dysmenorrhea,and dyspareunia. The cyst was extracted using laparoscopy, whilst in histopathologicalexamination, an actinomycosis super infection was reported. Actinomyc super infection of anovarian dermoid cyst is a very rare incident which can also occur in women with no history ofintrauterine device (IUD usage or previous fertility.

  5. Super infection of an ovarian dermoid cyst with actinomyces in an infertile woman.

    Science.gov (United States)

    Salehpour, Saghar; Akbari Sene, Azadeh

    2013-07-01

    We present super infection of an ovarian dermoid cyst with actinomyces in an infertile patient. This is a case-report study for evaluation a couple with male factor infertility, who was a good candidate for intracytoplasmic sperm injection (ICSI), while a 10 cm dermoid cyst was found in the woman's right ovary. Patient complained of pelvic pain, intermittent fever, dysmenorrhea, and dyspareunia. The cyst was extracted using laparoscopy, whilst in histopathological examination, an actinomycosis super infection was reported. Actinomyc super infection of an ovarian dermoid cyst is a very rare incident which can also occur in women with no history of intrauterine device (IUD) usage or previous fertility.

  6. Super Infection of An Ovarian Dermoid Cyst with Actinomyces in An Infertile Woman

    Science.gov (United States)

    Salehpour, Saghar; Akbari Sene, Azadeh

    2013-01-01

    We present super infection of an ovarian dermoid cyst with actinomyces in an infertile patient. This is a case-report study for evaluation a couple with male factor infertility, who was a good candidate for intracytoplasmic sperm injection (ICSI), while a 10 cm dermoid cyst was found in the woman’s right ovary. Patient complained of pelvic pain, intermittent fever, dysmenorrhea, and dyspareunia. The cyst was extracted using laparoscopy, whilst in histopathological examination, an actinomycosis super infection was reported. Actinomyc super infection of an ovarian dermoid cyst is a very rare incident which can also occur in women with no history of intrauterine device (IUD) usage or previous fertility. PMID:24520476

  7. Ultrasound-guided Transvaginal Aspiration in the Management of Actinomyces Pelvic Abscess

    Science.gov (United States)

    Rahav, Galiya; Hanoch, Josef; Shimonovitz, Shlomo; Yagel, Simcha; Laufer, Neri

    1996-01-01

    Background: Increasing reports of intrauterine device (IUD)-related abdominopelvic actinomycosis have been described recently. Surgical therapy has been the usual treatment when tubo-ovarian abscess is identified. Case: A 38-year-old woman suffering from Actinomyces pelvic abscess unresponsive to medical treatment underwent transvaginal ultrasound-guided needle aspiration. It resulted in marked improvement and avoided surgical treatment. Conclusion: Transvaginal needle aspiration of Actinomyces pelvic abscess may be an alternative to surgical therapy, thereby allowing the preservation of pelvic organs. PMID:18476111

  8. [IUD-associated pseudoactinomycotic gradiate granules (Spendore-Hoeppli phenomenon) in uterine curettage].

    Science.gov (United States)

    Padberg, B C; Kolb, S A; August, C; Schröder, S

    2002-03-01

    Pseudoactinomycotic radiate granules, also known as the Splendore-Hoeppli phenomenon represent a response to organic and in-organic foreign substances and can be found at various locations in the body. They are frequently observed in uterine curettages, where they can be misinterpreted as actinomycotic sulfur granules. Here we report a case with Splendore-Hoeppli phenomenon in an intrauterine device (IUD)-associated genital actinomycosis. The morphological features of this phenomenon are presented using special staining methods and electron microscopy and the literature is reviewed.

  9. Pseudoactinomycotic Radiate Granules (PAMRAGs)- An Unusual Differential Diagnosis for Ovarian Neoplasm; A Diagnostic Dilemma.

    Science.gov (United States)

    P J, Cicy; P J, Tessy; P, Lekshmidevi; V, Letha; Poothiode, Usha

    2015-03-01

    Pseudoactinomycotic radiate granules (PAMRAGs) are rarely detected lesions in ovary. Endometrium is the usual site and a detailed search of literature yielded only two cases in the ovary. PAMRAGs must be differentiated from actinomycotic granules which are also strongly associated with the use of intrauterine contraceptive devices (IUCDs). In cases of suppurative oophoritis due to actinomycosis, a proper diagnosis and culture confirmation is mandatory to avoid further complications. This case is reported due to its rarity, unusual clinical presentation and to highlight the importance of special stains in cases of tuboovarian abscess, where PAMRAGs may cause diagnostic dilemma. Our patient was a 50 yr old female admitted with clinical diagnosis of malignant ovarian tumour. After preoperative work up, panhysterectomy, infracolic omentectomy and excision biopsy of the right inguinal lymph node were done. Peroperatively the right ovary was enlarged and adherent to the fallopian tube and pelvic wall. Gross examination revealed a right tuboovarian mass with yellowish areas of necrosis and fibrosis. Histology showed a suppurative granulomatous lesion with spherical granules having club like peripheral projections. A panel of special stains (GMS, GRAMs and AFB) done were negative. Thus, we ruled out actinomycosis and gave a diagnosis of PAMRAG.

  10. In vitro actinomycete biofilm development and inhibition by the polyene antibiotic, nystatin, on IUD copper surfaces.

    Science.gov (United States)

    Shanmughapriya, Santhanam; Francis, Arumugam Lency; Kavitha, Senthil; Natarajaseenivasan, Kalimuthusamy

    2012-01-01

    The presence of intrauterine contraceptive devices (IUDs) gives a solid surface for attachment and an ideal niche for biofilm to form and flourish. Pelvic actinomycosis is often associated with the use of IUDs. Treatment of IUD-associated pelvic actinomycosis requires the immediate removal of the IUD. Therefore, this article presents in vitro evidence to support the use of novel antibiotics in the treatment of actinomycete biofilms. Twenty one clinical actinomycetes isolates from endocervical swabs of IUD wearers were assessed for their biofilm forming ability. An in vitro biofilm model with three isolates, Streptomyces strain A4, Nocardia strain C15 and Nocardia strain C17 was subjected to treatment with nystatin. Inhibition of biofilm formation by nystatin was found to be concentration dependent, with MBIC50 values in the range 0.08-0.16 mg ml(-1). Furthermore, at a concentration of 0.16 mg ml(-1), nystatin inhibited the twitching motility of the isolates, providing evidence for a possible mechanism of biofilm inhibition.

  11. New label broadens IUD candidacy profile. History of some diseases now just a precaution.

    Science.gov (United States)

    1995-05-01

    The Population Council recently reworded the package labeling for the copper T380A IUD as follows: pelvic inflammatory disease (PID) is related to a woman's sexual behavior and not to the device itself. Formerly contraindicated, histories of PID or ectopic pregnancy are now merely precautions. The labeling now warns that the Copper T is contraindicated in the presence of PID or in women with a history of PID since the last pregnancy. If a woman has been free of infection, there is no need not to give her an IUD. The former contraindication about ectopic pregnancy has been deleted, while contraindications in the section of the label on conditions associated with increased susceptibility to infections with microorganisms now include only leukemia and AIDS. IV drug use and conditions requiring chronic corticosteroid therapy have been dropped from the section, along with diabetes. Finally, the former contraindication of genital actinomycosis has been changed to address symptomatic genital actinomycosis with organism confirmed by culture. This latter change is due to the high number of false-positives seen with Pap smears alone. These changes are logical given recent research findings about IUDs. A brief overview is given of recent findings about IUDs with regard to pelvic inflammatory disease, ectopic pregnancy, and diabetes.

  12. Tuboovarian abscess mimicking intraligamentar uterine myoma and a intrauterine device: a case report.

    Science.gov (United States)

    Habek, D; Has, B; Habek, J Cerkez

    2005-09-01

    A case study is presented of tubo-ovarian abscess (pathohystological-verified actinomycosis) in a 41-year-old woman with an intrauterine device (IUD), which on US was found to be imposed upon an intraligamentary degenerated myoma (pyomyoma). The patient was afebrile, with normal vital functions (diuresis, blood pressure and pulse). Exposure of the abdominal cavity by lower transverse laparotomy performed under general endotracheal anaesthesia revealed slight uterus enlargement with normal left adnexa, whereas right adnexa were not exposed due to the soft tumour in the region of the right ligamentum latum, which displaced the urinary bladder and uterus leftward. The peritoneum fold was incised and deprepared, revealing a tumorous formation imposed onto the myoma or onto the 'cold' tubo-ovarian abscess. Total hysterectomy was then performed. Left adnexa showed a normal finding. Hemalaun-eosin staining of the preparation of the tumour capsule and tumour content showed colonies of threads extending radially to the surrounding tissues (drusen), surrounded by pus corpuscles, polymorphonuclears and macrophages containing lipids (sulfur granules). The patient was free from disease relapse at 2 years after the procedure. Thus, total abdominal hysterectomy and salpingoophorectomy, along with antibiotic therapy, were the definite mode of treatment for pelvic actinomycosis.

  13. The prevalence of actinomycetes-like organisms found in cervicovaginal smears of 300 IUD wearers.

    Science.gov (United States)

    Jones, M C; Buschmann, B O; Dowling, E A; Pollock, H M

    1979-01-01

    The association of Actinomyces with IUD wearers has been widely documented and the possibility of the recognition of actinomycetes-like organisms in routine Papanicolaou-stained cervicovaginal smears has been reported. We conducted a retrospective study of IUD wearers to determine the prevalence and significance of actinomycetes-like organisms found in such smears. Three hundred smears from current IUD wearers were rescreened for actinomycetes-like organisms. Of this group, 200 patients were from a public health family planning clinic, and 100 were private patients. The incidence for the public health group was 25.5% and for the private patient group, 8%. A case history of actinomycosis is included. Findings such as other infectious agents, abnormal cytology and symptoms are also discussed. Although the presence of Actinomyces probably represents an opportunistic infection, the threat of pelvic actinomycosis with serious complications poses a management problem to the clinician when Actinomyces is reported in a routine Papanicolaou smear. Our findings lead us to question the practicality of the earlier recommendations of IUD removal and antibiotic therapy.

  14. [Identification of environmental Actinobacteria representing an occupational health risk].

    Science.gov (United States)

    Skóra, Justyna; Szponar, Bogumiła; Paściak, Mariola; Gutarowska, Beata

    2013-12-06

    Actinobacteria, the etiologic agents of tuberculosis, actinomycosis, respiratory infections and pathological skin lesions, are also classified as hazardous biological agents at the workplace. An increased number of Actinobacteria primarily occurs at the workplaces in composting plants, agriculture, waste management facilities, libraries and museums. Robust identification of Actinobacteria requires a polyphasic diagnostic strategy including an assessment of morphological, physiological, biochemical and chemotaxonomic features as well as genotyping. Commercially available diagnostic kits often do not include bacteria isolated from the environment and therefore analyses of chemotaxonomic markers--components of peptidoglycan, fatty acids, polar lipids (phospho- and glycolipids) and isoprenoid quinones are recommended. The paper discusses a comprehensive approach to the isolation and identification of Actinobacteria, with emphasis on chemotaxonomic methods. A diagnostic procedure is exemplified by environmental strains obtained from composting plants and libraries.

  15. Aspergillosis and other systemic mycoses. The growing problem.

    Science.gov (United States)

    Fraser, D W; Ward, J I; Ajello, L; Plikaytis, B D

    1979-10-12

    To measure the incidence in the United States of systemic mycoses necessitating hospitalization, we reviewed discharge records of 1,875 hospitals participating in the Professional Activity Study of the Commission on Professional and Hospital Activities. Projected incidence rates in 1976 ranged from 23.0 per million for histoplasmosis to 0.2 per million for blastomycosis. High prevalences of leukemia or lymphoma (5.9% to 10.2%) or of other malignancies (9.9% to 13.2%) were recorded in patients with aspergillosis, candidasis, or cryptococcosis. High prevalences of chronic obstructive lung disease (9.6% to 9.9%) were recorded in those with aspergillosis or histoplasmosis. Marked increases from 1970 to 1976 were found in the incidence of aspergillosis (158%), actinomycosis (92%), cryptococcosis (78%), and coccidioidomycosis (74%). Increasing numbers of persons with immunosuppressive conditions, migration of susceptible persons into hyperendemic areas, and aging of the population contributed to the increases.

  16. Abscesso actinomicótico do cerebelo: relato de caso Actinomycotic abscess of the cerebellum: case report

    Directory of Open Access Journals (Sweden)

    Mário H. Tsubouchi

    1995-09-01

    Full Text Available Acometimento do sistema nervoso central por actinomicetos é extremamente raro. Os autores descrevem um caso de actinomicose de cerebelo, com diagnóstico estabelecido após remoção cirúrgica da lesão e tratamento com sucesso com penicilina endovenosa e oral. Breve revisão da literatura sobre o envolvimento do sistema nervoso na actinomicose é apresentada.A 38 year-old man presented fever and a clinical picture of intracranial hypertension and ataxic syndrome. A CT-scan disclosed an expanding lesion of the cerebellum. Surgical excision of the lesion was performed and pathological examination made the diagnosis of an actinomycotic abscess. The probable primary source of infection were the lungs and/or oral cavity. The postoperative course was uneventful, with complete recovery after a long period of treatment with penicillin (IV and PO. The authors review some aspects about central nervous system involvement in actinomycosis.

  17. Imaging of Chest Wall Lesions in Children

    Directory of Open Access Journals (Sweden)

    A. Hekmatnia

    2008-01-01

    Full Text Available Chest wall lesions in childhood include a wide range of pathologies; Benign lesions include lipoma, neurofibroma, lymphangioma, hemangioma, and mesenchymal hamartoma."nMalignant lesions include Neuroblastoma, Rhabdo-myosarcoma, Ewing sarcoma, and Askin tumor."nSystemic diseases such as leukemia, lymphoma, Langerhans cell histiocytosis, and also infections such as tuberculosis, and actinomycosis may also cause chest wall lesions."nThe imaging characteristics of these lesions are re-viewed, but only a minority of the lesions shows diagnostic imaging features, and most of lesions re-quire biopsy and histopathological examination for "ndefinitive diagnosis."nThe role of different modalities is discussed with an emphasis on magnetic resonance imaging for demonstrating lesion morphology and local spread. Computed tomography and neuclear medicine being used mainly to assess remote disease."nIn this lecture, we discuss about imaging of chest wall lesions in children.

  18. Botryomycosis Due to Staphylococcus Aureus-A Case Report

    Directory of Open Access Journals (Sweden)

    Manjula A.Vagarali

    2012-04-01

    Full Text Available Objectives: To study Staphylococcus aureus as the causative organism of botryomycosis. Background: the botryomycosis is a chronic purulent granulomatous lesion of the skin, subcutaneous tissue and visceral organs caused by several bacterial species. This condition clinically and histopathologically resembles with that of mycetoma and Actinomycosis. Method: A 51 year old male presented to us with swelling over medial aspect of the right foot with multiple sinuses. He gave a history of trauma 3 years back at the same site. The sample was examined directly by KOH preparation and grams stain. The culture was put up on blood, chocolate, lowenstein Jensen (LJ and sabouraud dextrose agar (SDA media. Fungal culture was negative. Result: Staphylococcus aureus was isolated in aerobic culture. Conclusion: the patient with botryomycosis caused by Staphylococcus aureus was subsequently treated with antibiotics and he recovered completely.

  19. ESTUDO ANATOMOPATOLÓGICO EM TECIDOS CONDENADOS PELO SERVIÇO DE INSPEÇÃO FEDERAL (SIF POR SUSPEITA DE TUBERCULOSE

    Directory of Open Access Journals (Sweden)

    Ricardo Evandro Mendes

    2013-12-01

    Full Text Available The methodology used during the Animal Standard Meat Inspection (SIS has been controversial in the decision to condemn or approve materials for human consumption. The aim of this study was to identify the microscopic lesions found in lymph node tissues condemned for tuberculosis by the Brazilian SIS. Sixty-one condemned lymph nodes were collected, fixed in buffered formalin 10% and submitted to histological processing. By evaluating the condemned tissues with H&E stain, 55 tuberculoid granuloma were found, as well as three actinomycosis granuloma, 2 presenting lymphoid hyperplasia and 1 crystal deposition. The misdiagnosis rate in the samples condemned due to tuberculosis was satisfactory, however it can be improved.

  20. Leucocyte-rich and platelet-rich fibrin for the treatment of bisphosphonate-related osteonecrosis of the jaw: a prospective feasibility study.

    Science.gov (United States)

    Kim, Jin-Woo; Kim, Sun-Jong; Kim, Myung-Rae

    2014-11-01

    Our aim was to assess the feasibility of using leucocyte-rich and platelet-rich fibrin (L-PRF) for the treatment of bisphosphonate-related osteonecrosis of the jaw (BRONJ) in a single group study. After treatment with L-PRF, the response of each patient was recorded 1 month and 4 months postoperatively. Further assessments were made of the site, stage, concentration of c-terminal crosslinked telopepide of type 1 collagen, and actinomycosis. Among the total of 34 patients, 26 (77%) showed complete resolution, 6 (18%) had delayed resolution, and 2 (6%) showed no resolution. There was a significant association between the response to treatment and the stage of BRONJ (p=0.002) but no other significant associations were detected. This study has shown that it is feasible to use L-PRF for the treatment of BRONJ, but the effectiveness cannot be judged with this study design. Randomised prospective trials are needed to confirm this.

  1. Colitis and lower abdominal mass by Actinomyces israelii in a patient with an IUD.

    Science.gov (United States)

    Nugteren, S K; Ouwendijk, R J; Jonkman, J G; Straub, M; Dees, A

    1996-08-01

    Abdominal actinomycosis is a rare disorder. The diagnosis is frequently missed preoperatively. We describe a patient who had had an intrauterine contraceptive device in situ for 5 years. She presented with a painful pelvicoabdominal mass, located between the uterus and rectum, and a colitis-like disease of the distal colon. Culture of the removed IUD demonstrated Actinomyces. She was intensively treated with intravenously penicillin for six weeks. Following this conservative treatment the abdominal tumor and the colitis-like symptoms totally disappeared. During two years follow-up she is free of symptoms and no signs of recurrence of the disease have been noticed. The case described here strongly underlines that Actinomyces infection should be born in mind in the differential diagnosis of a young female with an IUD, presenting with colitis, fever and an abdominal mass. Prolonged intravenously administered penicillin is warranted before surgery should be considered.

  2. Actinomyces in the endometrium of IUD users.

    Science.gov (United States)

    Aubert, J M; Gobeaux-Castadot, M J; Boria, M C

    1980-06-01

    The colonization of the female genital tract with Actinomyces is closely related to the presence of an IUD in the uterine cavity. This was confirmed in the present study, which shows an Actinomyces frequency of over 3% in users of IUDs, while non-users were free from the opportunistic invader. This frequency was higher with certain types of devices than with others. None of the patients with positive results had pelvic symptoms, but cases of serious infections have been reported in the literature. The length of IUD usage appears to be directly related to the incidence of this colonization. The possible pathogenesis of pelvic actinomycosis is presented; the clinical significance of asymptomatic colonization is discussed.

  3. Systemic Actinomyces infection. A potential complication of intrauterine contraceptive devices.

    Science.gov (United States)

    de la Monte, S M; Gupta, P K; White, C L

    1982-10-15

    Infections caused by Actinomyces organisms have been demonstrated to occur in association with IUD use. Uterine actinomycosis infection is usually superficial, but it is potentially invasive. It may prove fatal. When Actinomyces is detected in a vaginal Papanicolaou smear, establishment of the correct diagnosis followed by IUD removal and appropriate antibiotic therapy are recommended. A case history is presented of a 28 year old woman who had been using an IUD and who had systemic Actinomyces infection and a brain abscess develop several years after removal of her uterus and fallopian tubes. The woman was referred to the Johns Hopkins Hospital in Baltimore in 1977 for evaluation of headaches and grand mal seizures. 4 years earlier, in 1973, she had been seen at another hospital with a recent weight loss of 18 kg. She was found to have a tubo-ovarian abscess, for which she underwent a hysterectomy, bilateral salpingectomy, and unilateral oophorectomy. At the time of surgery, an IUD was in place. A histopathological diagnosis of botryomycosis tubo-ovarian abscess was made on submitted tissues. She received no antibiotic therapy. In 1975, pulmonary infiltrates developed that were attributed to bronchopneumonia. She was treated with a short course of tetracycline hydrochloride. Later that year she was thought to have sarcoidosis and was treated for 1 year with several doses of prednisone. Clinically, her condition remained stable until March 1977, when a pyogenic subcostal abscess was drained. In July 1977, she had headache, dizziness, generalized seizures, and an incomplete right homonymous hemianopsia develop. A craniotomy for excision and drainage of an abscess was performed. The presence of Actinomyces israelii in brain tissue was confirmed by direct immunoflourescence using specific antiserum. It was confirmed that Actinomyces had been present at the time of her 1st surgical procedure. She was treated with high doses of intravenous penicillin G potassium for the

  4. A Para-Canalicular Abscess Resembling an Inflamed Chalazion

    Directory of Open Access Journals (Sweden)

    Diamantis Almaliotis

    2013-01-01

    Full Text Available Background. Lacrimal infections by Actinomyces are rare and commonly misdiagnosed for long periods of time. They account for 2% of all lacrimal diseases. Case Report. We report a case of a 70-year-old female patient suffering from a para-canalicular abscess in the medial canthus of the left eye, beside the lower punctum lacrimale, resembling a chalazion. Purulence exited from the punctum lacrimale due to inflammation of the inferior canaliculus (canaliculitis. When pressure was applied to the mass, a second exit of purulence was also observed under the palpebral conjunctiva below the lacrimal caruncle. A surgical excision was performed followed by administration of local antibiotic therapy. The histopathological examination of the extracted mass revealed the existence of actinomycosis. Conclusion. Persistent or recurrent infections and lumps of the eyelids should be thoroughly investigated. Actinomyces as a causative agent should be considered. Differential diagnosis is broad and should include canaliculitis, chalazion, and multiple types of neoplasias. For this reason, in nonconclusive cases, a histopathological examination should be performed.

  5. Empiema por Actinomyces: el gran simulador Empyema due to Actinomyces: a diagnostic challenge

    Directory of Open Access Journals (Sweden)

    Fernando J. Vázquez

    2006-02-01

    Full Text Available El derrame pleural aislado, como única manifestación de la actinomicosis es una situación muy rara y un desafío diagnóstico para el clínico, no sólo por su infrecuencia sino por la dificultad técnica para cultivar al gérmen. La típica apariencia microscópica de este bacilo Gram-positivo ramificado en los cultivos suele ser la clave del dianóstico. Se informa un caso de derrame pleural masivo izquierdo por Actinomyces israelii, sin afectación del parénquima pulmonar, de difícil diagnóstico, que mejoró clínica y radiológicamente en forma completa con el drenaje quirúrgico y tratamiento antibiótico prolongado.Isolated pleural effusion due to actinomycosis is rare and poses a diagnostic challenge to clinicians not only because it is uncommon and often forgotten, but also because culture of the causative microorganism is technically difficult. The classic al microscopic appearance of this Gram-positive bacillus on cultures often forms the basis of diagnosis. This is the report of a case of massive left sided pleural effusion due to Actinomyces israelii that improved clinically and radiologically after surgery and prolonged antibiotic treatment.

  6. IUD patient selection and practice guidelines.

    Science.gov (United States)

    Nelson, A L; Sulak, P

    1998-01-01

    Contraceptive practice guidelines have the potential to assist health care providers in evaluating the needs and expectations of women seeking contraception, educating patients, and monitoring successful contraceptive use. This article presents guidelines for IUD patient selection developed by several members of the editorial board of the US newsletter, "Dialogues in Contraception." Misinformation about the IUD has prevented many clinicians and patients from considering this method, despite recent improvements in its design. The currently available data suggest that the two IUDs available in the US, Copper T 380A and Progestasert, cause a local reaction that is toxic to sperm (and perhaps ova), thereby preventing fertilization. Modern IUDs, which use only monofilament tails, do not increase the risk of pelvic inflammatory disease in women without evidence of lower genital tract infection. Beyond avoiding women at risk for sexually transmitted diseases, there are few barriers to IUD use. The method is appropriate for women who are contemplating but ambivalent about sterilization, aged under 25 years, perimenopausal, nulliparous or parous, postpartum or postabortion, lactating, and cigarette smokers over 35 years of age. Contraindications to IUD use are postpregnancy infection, unresolved acute cervicitis or vaginitis, distorted uterine cavity, uterine or cervical cancer, unexplained abnormal vaginal bleeding, increased susceptibility to infection, genital actinomycosis, immunocompromised patients, and diabetes mellitus (progesterone-releasing IUD only).

  7. [Lupus vulgaris as a complication of pulmonary tuberculosis--case report].

    Science.gov (United States)

    Owczarek, Witold; Targowski, Tomasz; Kozera-Zywczyk, Anna; Paluchowska, Elwira; Patera, Janusz

    2009-10-01

    Tuberculosis is a contagious disease induced by Mycobacterium species, acid-fast bacilli. These are mostly human type--Mycobacterium tuberculosis, less often cattle type--mycobacterium bovis or other: mycobacterium avium, kansasii, marinom, scrofulaceum, heamophilium, gordonae. The infection can affect all organs, but pulmonary tuberculosis is the most common form. The importance of tuberculosis is definitely rising in the context of massive population migrations in regions affected by its higher incidence, increased HIV infections and AIDS development. Cutaneous tuberculosis is a particular tuberculosis form with differentiated clinical picture. Non-typicalness of skin changes and oligobacilleous course of extrapulmonary tuberculosis forms are repeatedly causing difficulties in adequate diagnosis and early treatment. In differential diagnostics of cutaneous tuberculosis one must take leishmaniasis, actinomycosis, leprosy, syphilis and deep mycosis (among others) into consideration. The study is presenting a case of lupus vulgaris as a complication of past pulmonary tuberculosis. In bacteriological diagnostics of skin changes bioptates, no tuberculosis mycobacteria were found. The disease was diagnosed based on specific granulation presence in histopathology test, tuberculin hypersensivity, bacilli DNA presence in polymerase chain reaction (PCR) test and skin changes regression after anti-mycobacterium treatment. According to authors of the study, the described case confirms the usefulness of PCR nucleonic acids amplification test in cutaneous tuberculosis diagnosis.

  8. Spontaneous perforation of the small intestine, a novel manifestation of classical homocystinuria in an adult with new cystathionine beta-synthetase gene mutations.

    Science.gov (United States)

    Muacević-Katanec, Diana; Kekez, Tihomir; Fumić, Ksenija; Barić, Ivo; Merkler, Marijan; Jakić-Razumović, Jasminka; Krznarić, Zeljko; Zadro, Renata; Katanec, Davor; Reiner, Zeljko

    2011-03-01

    The clinical picture of classical homocystinuria is diverse. This is the first report of an adult homocystinuric patient with non-traumatic spontaneous small bowel perforation. A 47-year old man presented with abdominal rebound tenderness, hypotension and tachycardia, anemia, and elevated markers of inflammation. Other routine laboratory tests were normal. Abdominal x-ray showed no free air. An emergency laparotomy revealed jejunal perforation in the left upper quadrant. Histologic specimen showed full-thickness nonspecific inflammation of the intestinal wall with granulocytic infiltration, hemorrhage and necrosis. Tuberculosis, actinomycosis and typhus were histologically and clinically excluded. After excluding all known possible causes of perforation, we presumed a causative relationship between homocystinuria and small bowel perforation. It could be hypothesized that connective tissue weakness in homocystinuria is a result of homocysteine interference with recombinant human fibrillin-1 fragments or cross-linking of collagen through permanent degradation of disulfide bridges and lysine amino acid residues in proteins. DNA analysis showed three detectable mutations in the cystathionine beta-synthetase gene, 1278T:c.833T>C, and two new mutations, V372G:c.1133T > G, and D520G:c.1558A > G in the aternatively spliced exon 15.

  9. A para-canalicular abscess resembling an inflamed chalazion.

    Science.gov (United States)

    Almaliotis, Diamantis; Nakos, Elias; Siempis, Thomas; Koletsa, Triantafyllia; Kostopoulos, Ioannis; Chatzipantazi, Maria; Karampatakis, Vasileios

    2013-01-01

    Background. Lacrimal infections by Actinomyces are rare and commonly misdiagnosed for long periods of time. They account for 2% of all lacrimal diseases. Case Report. We report a case of a 70-year-old female patient suffering from a para-canalicular abscess in the medial canthus of the left eye, beside the lower punctum lacrimale, resembling a chalazion. Purulence exited from the punctum lacrimale due to inflammation of the inferior canaliculus (canaliculitis). When pressure was applied to the mass, a second exit of purulence was also observed under the palpebral conjunctiva below the lacrimal caruncle. A surgical excision was performed followed by administration of local antibiotic therapy. The histopathological examination of the extracted mass revealed the existence of actinomycosis. Conclusion. Persistent or recurrent infections and lumps of the eyelids should be thoroughly investigated. Actinomyces as a causative agent should be considered. Differential diagnosis is broad and should include canaliculitis, chalazion, and multiple types of neoplasias. For this reason, in nonconclusive cases, a histopathological examination should be performed.

  10. The incidence of actinomyces-like organisms in Papanicolaou-stained smears of copper- and levonorgestrel-releasing intrauterine devices.

    Science.gov (United States)

    Merki-Feld, G S; Lebeda, E; Hogg, B; Keller, P J

    2000-06-01

    Actinomyces-like organisms (ALOs) are a common finding in Papanicolaou-stained cervico-vaginal smears (PAP smears) of women using an intrauterine device (IUD). The incidence of ALOs positive PAP smears depends on the type of IUD. Pelvic actinomycosis is a severe disease that may require hysterectomy and salpingo-oophorectomy. In a retrospective study we compared the incidence of ALOs positive PAP smears in users of the new levonorgestrel-releasing intrauterine device (LNG-IUD) (n = 52) with the incidence in Multiload Copper IUD (ML375) users (n = 104). All IUDs had been inserted from 1996-1998. Women with a follow-up period of more than 9 months were included into the final analysis (LNG-IUD: n = 34; ML375: n = 65). The incidence of ALOs in LNG-IUD users (2.9%) was significantly lower than in ML375 users (20%). Clinical consequences of ALOs positive PAP smears are discussed controversially. The low incidence in the LNG-IUD users probably leads to less IUD-removals, reinsertions and less pelvic-inflammatory-diseases.

  11. Actinomyces-like organisms in cervical smears: the association with intrauterine device and pelvic inflammatory diseases

    Science.gov (United States)

    Kim, Yeo Joo; Youm, Jina; Kim, Jee Hyun

    2014-01-01

    Objective To investigate the incidence of actinomyces-like organisms in routine cervical smears of Korean women and to evaluate its association with the development of pelvic inflammatory disease (PID) in these women. Methods The results of cervical smears between 2011 and 2012 at a single university hospital were searched. If positive for actinomyces-like organisms, the medical record of the patient was searched and development of PID was followed. If the data were not available in the medical record, the patient was contacted by telephone. Results The incidence of actinomyces-like organisms in cervical smears was 0.26% (52/20,390). Forty-two women (80.8%) were intrauterine device (IUD) users: the copper-IUD in 25 women and the levonorgestrel-releasing intrauterine system in 13 women (type unknown in 4 women). The majority (71.4%, 30/42) of the IUD users maintained the IUD. Prophylactic antibiotics were prescribed to 12 women. Two continuous IUD users were later diagnosed with PID, but these cases were not pelvic actinomycosis. Conclusion It would be a reasonable option to choose the expectant management for asymptomatic women who incidentally showed actinomyces-like organisms in their cervical smear. PMID:25264530

  12. 保护性耕作对黄土旱塬玉米土壤呼吸及微生物数量的影响%Effects of conservation tillage on soil respiration and microorganism amount in maize rhizosphere soil in Loess Plateau

    Institute of Scientific and Technical Information of China (English)

    杨倩; 张清平; 蒋海亮; 杨德雄; 王先之; 沈禹颖

    2012-01-01

    The study was executed to analyze the influence of no tillage and residue retention on soil respiration and microorganism of maize rhizosphere soil in Qingyang Loess plateau after 10 years' implementation of conservation tillage. Soil respiration was measured using LI-COR-6400-09, soil Respiration Chamber completed with Infrared Gas Analyzer under 10-years conservation tillage, and microorganism amount of maize rhizosphere soil was measured by the method of dilution plate counting. The results showed that no tillage and residue retention significantly decreased the soil respiration rates of maize anthesis by 8.3 and 7.8%as well as harvesting period by 15.5% and 13.6%. The top 10 cm ground temperature and the soil respiration rates were the same and the top 10 cm ground temperature under traditional tillage treat ment was the highest. The amount of bacteria, fungi and actinomycosis under no tillage and residue reten- tion were higher than that in conventional tillage treatment and the ratio between three kinds microbe was not changed. Soil respiration rate had negative correlation with the amount of bacteria, fungi and actinomycosis, which was not significant (P〈0.05). Many factors can influence the soil respiration rate, and the soil temperature was the main factor for soil respiration rate.%研究了实施保护性耕作10年后秸秆还田和免耕对土壤可培养微生物数量和CO2释放的影响,采用LI—COR-6400—09土壤气室连接红外线气体分析仪测定了玉米(Zea mays cv.Zhongdan No.2)土壤呼吸速率,采用平板涂抹计数法测定了根际土壤细菌、真菌和放线菌数量。结果表明,免耕和秸秆还田处理玉米花期土壤呼吸速率降低了8.3%和7.8%,玉米收获期土壤呼吸速率降低了15.5%和13.6%;土壤10cm处地温与土壤呼吸速率变化趋势一致,且在传统耕作处理下最高;与传统耕作相比,免耕和秸秆还田不同程度地增加了根际土

  13. A CLINICOPATHOLOGICAL STUDY OF CUTANEOUS GRANULOMA

    Directory of Open Access Journals (Sweden)

    Bornali

    2016-03-01

    Full Text Available BACKGROUND A wide range of immunologic and non-immunologic causes can lead to the formation of a granuloma. The aetiological agent and immunological status of the host determines the clinical presentation of these chronic skin lesions. However, diagnosis often becomes intricate as different clinical types present with morphological similarities, which gets further complicated by time and presumptive therapy. AIMS To study the incidence and clinical pattern of cutaneous granulomas; their relationship with age, sex, trauma and determine the importance of laboratory tests, specially histopathology in confirming aetiological diagnosis. SETTINGS AND DESIGN Cross-sectional study, based on hospital records. METHODS AND MATERIAL The study was from OPD records of Department of Dermatology and Venereology. All patients who had attended with clinically suspected cutaneous granulomatous lesions and underwent investigative procedures over a one-year period were included in the study. The relevance of the investigative procedures used, especially histopathology in arriving at the final diagnosis was established. Statistical analysis used: Descriptive statistical analysis and Chi-square test whenever appropriate. RESULTS AND CONCLUSIONS A total of 300 cases of cutaneous granuloma were included in the study. There was a male preponderance. The commonest cutaneous granuloma encountered was leprosy followed by fungal and tubercular granuloma. Less frequently encountered forms were syphilis, foreign body, parasitic, lymphogranuloma venereum, actinomycosis, rhinoscleroma, donovanosis and granulomatous mycosis fungoides. A total of 83.39% cases showed clinic-histopathological correlation. Cutaneous granulomas cause diagnostic difficulty due to clinical diversity and mimicry. Cutaneous granulomas of similar origin can present with varied clinical presentations, while those from different backgrounds can have similar presentations. A histopathological examination

  14. [The role of intrauterine contraceptive devices in the development of inflammatory processes in the small pelvis].

    Science.gov (United States)

    Batar, I

    1986-08-10

    The incidence of pelvic inflammatory disease (PID) attributable to IUD use has been increasing, especially after the removal of the Dalkon shield from the market, but this relationship has not been settled conclusively. In recent decades PID included a variety of infections, but lately the definition of PID has meant acute ascending infections of the female genital tract. Its most common risk factors include promiscuity of IUD use, although this can be reduced to one fourth by regular checkups and proper hygiene. The frequency of PID is estimated at 2-5% of IUD users. Microorganisms contributing to PID include Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma hominis, Escherichia coli, Proteus, Staphylococcus epidermis, Haemophilus influenzae, Bacteroides, Peptococcus, Peptostreptococcus, Clostridium, and Actinomyces israelii, The differentiation of actinomycosis (AC) and pseudoactinomycosis (PAC) is well advised. The potential of IUD use in increasing the risk of AIDS should not be discounted. The clinical picture of PID is varied, it can be mild requiring conservative drug therapy; with medium severity requiring removal of the IUD and drug therapy; severe necessitating removal, antibiotics and sulfonamide treatment and laparotomy; and very severe with potentially fatal generalized sepsis. In addition to antibiotics, e.g., penicillin, treatment can include the so called catastrophy combination of Mandokef- Metronidazol-Gentamycin. An analysis of the data of 8536 IUD fittings in Debrecen, Hungary showed 1.4% removals due to PID after 4 years, 694 patients (8.1%) had lower abdominal pain 73 of which (0.9%) had palpable resistance, and suppuration occurred in only 30 cases (0.4%). Treatment included Semicillin or Tetran, or removal of the IUD, and even surgery if no improvement resulted. Prevention of PID include elimination of risk factors, the careful selection of IUD users, regular checkups, the use of copper (Cu) T device, and strict adherence to

  15. Assessing Fifty Years of General Health Surveillance of Roe Deer in Switzerland: A Retrospective Analysis of Necropsy Reports

    Science.gov (United States)

    Pewsner, Mirjam; Origgi, Francesco Carlo; Frey, Joachim; Ryser-Degiorgis, Marie-Pierre

    2017-01-01

    General wildlife health surveillance is a valuable source of information on the causes of mortality, disease susceptibility and pathology of the investigated hosts and it is considered to be an essential component of early warning systems. However, the representativeness of data from such surveillance programs is known to be limited by numerous biases. The roe deer (Capreolus capreolus capreolus) is the most abundant ungulate and a major game species all over Europe. Yet, internationally available literature on roe deer pathology is scarce. The aims of this study were (1) to provide an overview of the causes of mortality or morbidity observed in roe deer in Switzerland and to assess potential changes in the disease pattern over time; and (2) to evaluate the value and limitations of a long term dataset originating from general wildlife health surveillance. We compiled 1571 necropsy reports of free ranging roe deer examined at the Centre for Fish and Wildlife Health in Switzerland from 1958 to 2014. Descriptive data analysis was performed considering animal metadata, submitter, pathologist in charge, laboratory methods, morphological diagnoses and etiologies. Recurrent causes of mortality and disease pictures included pneumonia, diarrhea, meningoencephalitis, actinomycosis, blunt trauma, predation, neoplasms and anomalies. By contrast, other diagnoses such as fatal parasitic gastritis, suspected alimentary intoxication and reproductive disorders appeared only in earlier time periods. Diseases potentially relevant for other animals or humans such as caseous lymphadenitis (or pseudotuberculosis), salmonellosis, paratuberculosis and listeriosis were sporadically observed. The disease pattern in roe deer from Switzerland was largely in accordance with previous reports. The observed fluctuations were consistent with methodical and/or personnel changes and varying disease awareness. Nevertheless, despite such limitations, the compiled data provide a valuable baseline. To

  16. Actinomyces and an unidentified ameba associated with an intrauterine device.

    Science.gov (United States)

    Pien, F D; Navin, J J; Carty, F

    1981-05-01

    A case report is presented of an asymptomatic 29-year-old Hawaiian patient with an IUD who had Actinomyces and an unidentified ameba in a Papanicolaou smear and in whom both organisms disappeared upon removal of the IUD. The patient presented for a routine pelvic examination as part of an employment physical. She denied any significant gastrointestinal or vaginal symptoms as well as any history of foreign travel. The patient reported that she had worn the same IUD for 9 years and that it had caused her no discomfort. A pelvic examination revealed a friable, papular cervix. The Papanicolaou smear revealed the presence of both amebae and colonies of Actinomyces. The findings were confirmed by the Armed Forces Institute of Pathology, which reported an intense, acute and chronic inflammatory reaction marked by the presence of amebae and Actinomyces species colonies. The patient returned 4 months later for a repeat pelvic examination and removal of her IUD. At that time a cervical smear showed only amebae. The patient was seen again 3 months following the IUD removal. She reported that her vaginal discharge had decreased. A repeat Papanicolaou smear was completely normal. Faulkner and Ory have reported a 5-fold increase of pelvic inflammatory disease among IUD users compared to nonusers. Among pelvic infections found to be associated with IUD users is genital actinomycosis. Many of these patients are asymptomatic with only cytologic evidence of Actinomyces, but these patients can progress to pelvic inflammation and abscess formation. Reports have recently described the presence of amebic trophozoites in IUD users. The main purpose in reporting this case is to alert the tropical medicine specialist to this entity. Amebic colonization appears to respond completely to IUD removal, and there is no need for additional medical or surgical treatment.

  17. Actinomyces israelii in the female genital tract: a review.

    Science.gov (United States)

    Evans, D T

    1993-02-01

    Actinomyces israelii (a gram-positive, branching, anaerobic or microaerophilic bacterium) infects 1.6-11.6% of IUD users worldwide. Physicians must decide whether to treat A. israelii infection with antibiotics, remove the IUD, or refer the patient to the family planning clinic. Culture techniques tend to be inadequate, so many US health professionals use a microscope to identify A. israelii and often confirm the microscopy findings with direct immunofluorescent techniques. A sophisticated culture from pelvic infection or abscesses is needed. It appears that A. israelii infection is more common in women with plastic IUDs than those with copper IUDs and in women who have had an IUD for more than 4 years. Pelvic actinomycotic disease occurs infrequently, but when it does this condition the right ovary and fallopian tube are generally involved; this condition can be life threatening. It is indistinguishable from other forms of pelvic inflammatory disease. Evidence suggests that there is a cause-and-effect relationship between IUD use and pelvic actinomycosis. It is difficult to predict which IUD users harboring A. israelii will develop subsequent serious pelvic infection. Nevertheless, Pap smears can detect A. israelii infection early so physicians can prophylactically treat it before it spreads. Prophylactic treatment in IUD users may consist of changing the IUD every 4 years of long term penicillin or doxycycline treatment. Combinations of various antibiotics used to treat actinomyces infection are penicillin, aminoglycoside, chloramphenicol, amoxycillin, metronidazole, and doxycycline. In the case of tubo-ovarian abscesses larger than 8 cm in diameter, however, surgical treatment is warranted.

  18. A PROSPECTIVE STUDY OF CERVICAL LYMPHADE NOPATHY IN 78 CHILDREN IN TERTIARY HOSPITAL : IN KERALA

    Directory of Open Access Journals (Sweden)

    Sunil Kumar

    2015-04-01

    Full Text Available OBJECTIVE: To study the clinical presentation, result of diagnostic work up and treatment pattern of cervical lymphadenopathy in 78 children attending a tertiary referral Hospital attached to Government Medical College, Kozhikode; Kerala; to evolve a specific managem ent strategy and follow up in the Hospital for such patients. INTRODUCTION: Cervical lymphadenopathy in children is a common clinical entity seen in the OPD of ENT department. It can be due to extra pulmonary tuberculosis or Atypical Mycobacterium causing lymphadenitis, suppurative lymphadenitis. It can also be due to diseases like infectious mononucleosis, cat scratch disease, brucellosis, actinomycosis, nocardiosis, toxoplasmosis, malignancies (especially lymphoma, and cystic hygroma. Tuberculous lymphad enopathy is usually considered as a local manifestation of a systemic TB disease and reactive lymphadenitis as a localized disease due to local, focal septic foci. MATERIALS AND METHODS: A Prospective study is done in 78 children presenting with masses in the neck to the department of ENT. 49 children are females and 29 patients are males. Children are divided into two groups. Group A Patients clinically presenting with TB cervical lymphadenopathy (TLC. Group B patients clinically presenting with atypical TB cervical lymphadenitis (non - TLC . Unilateral Neck masses are seen in 59 patients and Bilateral in 19 patients. Involvement of Superficial jugular cervical group is seen in 23 children, supraclavicular involvement in 23 children, posterior triangle masses in 12 and upper deep glands in 15 patients. Anorexia, fever, malaise are found in 47% of the patients. Hematological investigations, ZN staining, FNAC, Biopsy - HPE and PCR investigations are done to clinch the final diagnosis. Four drug chemotherapy in gro up A and Chemotherapy combined with Surgery in group B patients is undertaken. RESULTS: Mantoux test is positive in 58.97% children. FNAC helped in 57.69% of the children

  19. Microbial and cytopathological study of intrauterine contraceptive device users

    Directory of Open Access Journals (Sweden)

    Agarwal Krishna

    2004-09-01

    vaginosis rate were not significantly different in two groups. Vaginal discharge bacterial culture revealed comparable results in two groups. Cytological findings were predominantly inflammatory. None of cases revealed Actinomycosis infection. High-grade squamous intraepithelial lesion (n=2 and low grade squamous intraepithelial lesion (n=1 cytological finding were present in IUCD users compared to none in controls. None of the cases had any malignant transformation. CONCLUSION: IUCD use results in lower hemoglobin concentration and cervical erosion. Women using IUCD requires a regular follow up, clinical examination, counseling and further investigation if required.

  20. 水稻连续免耕抛栽对土壤理化和生物学性状的影响%EFFECTS OF CONTINUOUS NO TILLAGE AND CAST TRANSPLANTING ON SOIL PHYSICAL, CHEMICAL AND BIOLOGICAL PROPERTIES

    Institute of Scientific and Technical Information of China (English)

    吴建富; 潘晓华; 石庆华; 漆英雪; 刘宗发; 胡金和

    2009-01-01

    A three year (2005~2007) experiment was conducted in paddy fields under a double rice cropping system to study effects of continuous no tillage and cast-transplanting on soil physical, chemical and biological properties. Results show that no-tillage treatment for one year (two crops)improved soil physical properties, but no-tillage treatment for three years (six crops), worsened soil physical properties. However, the effect of no tillage treatment for two years varied. In the soil incorporated with milk vetch and rice straw, it decreased soil density of the cultivated horizon, but increased total porosity and non-capillary porosity therein, and helped nutrient enrichment in the surface soil layer. Soil analysis showed that the no-tillage field was less than the control, plowed field in total amount of three groups of soil microbes. However, in no-tillage field, the amount of soil bacteria increased, while that of soil actinomycosis and fungi reduced, and urease activity in surface layer soil increased, while catalase and peroxidase activity reduced. Significantly positive correlations were observed of soil organic matter and total N with urease, catalase and polyphenol oxidase activity and, significantly positive correlations of soil total N and available K with peroxidase activity and. The findings provide a valuable reference for popularization and application of the technology of no-tillage and cast transplantation of rice in the future.%于2005~2007年在双季稻田以翻耕处理为对照,研究了水稻连续免耕抛栽对土壤理化和生物学性质的影响.结果表明,稻田免耕1年(2季),有利于土壤物理性状的改善,随着免耕时间(3年6季)的延长,土壤物理性质变差.但免耕2年后,采用紫云英和稻草还田能降低免耕稻田的土壤容重,提高总孔隙度和非毛管孔隙度.免耕有利于土壤养分在表层土壤富集.土壤中三大类微生物总量免耕处理小于翻耕处理,免耕土壤细菌的数

  1. 菌剂与缓释肥配施对复垦土壤微生物生态的影响%Efficiency of Mixed the Microbial Agent and Slow-release Fertilizer on Reclaimed Soil's Microbial Ecology

    Institute of Scientific and Technical Information of China (English)

    胡可; 王利宾; 杜慧玲

    2011-01-01

    在盆栽模拟复垦的条件下,利用传统平板计数法与BIOLOG方法相结合研究菌剂与缓释肥配施对土壤微生物生态的影响。结果表明,菌剂与缓释肥配施能显著提高土壤细菌、真菌和放线菌的数量。同时对土壤酶活性也具有有明显的影响。就脲酶而言,由于缓释肥与菌剂的配合施用,抑制了其活性,延长了缓释肥的肥效。通过对磷酸酶的研究发现,由于菌剂的加入促进了磷酸酶的活性,菌剂与缓释肥配施处理的土壤磷酸酶活性显著高于纯化肥处理的。通过多样性指数的测定表明菌剂与缓释肥配施处理土壤微生物群落的Shannon多样性指数、Simpson多样性指数和McIntosh均匀度等各项指标均显著高于其他处理的。说明菌剂与缓释肥配施不但可以提高土壤微生物功能多样性,而且还可以提高土壤微生物群落均匀度,从而可促进土壤微生物生态系统的稳定,提高土壤微生物群落的生态功能。%This experiment aimed at researching on the microbial ecology of microbial agent mixed with slow-release fertilizer by using the method that plate count method and BIOLOG microplate technique.The experiment adopted the method of cultivating potted plants in a greenhouse by reclaimed soil.Appling microbial agent mixed with slow-release fertilizer could increase qualities of bacteria,fungus and actinomycosis remarkably.In addition,appling microbial agent mixed with slow-release fertilizer could enhance the activities of soil enzymes.It could also extend the efficiency of controlled release fertilizer.But it could inhibit the activities of urea enzymes.To phosphoric enzymes,it enhanced its efficiency,and it had an remarkable advantages over pure chemical fertilizer.The results also demonstrated that the Shannonn and Simposn index and Mcintosh evenness with microbial agent and slow-release fertilizer addition were higher than those of other treatments.Microbial agent and slow

  2. 兰陵地区子宫颈液基细胞学筛查结果分析%Liquid-based cytology screening for cervical cancer in Lanling district

    Institute of Scientific and Technical Information of China (English)

    张丽冉; 王新国; 谢凤祥; 赵东曼; 范波涛; 李欣; 祁德波

    2015-01-01

    on stratified cluster sampling. Samples were stained by the pap method,analyzed by LCT and diagnosed based on the Tethesda system. Results Screening was completed for 99.96%of the 13,832 samples. Of the 13,832 samples analyzed,90 (0.72%)showed Candida albicans infection;120 (0.87%),vaginal trichomoniasis;30(0.22%),actinomycosis;and 770(5.57%),bacterial vaginosis. A total of 1,019 women(7.37%) showed microbial infections and 834(6.03%)showed cell abnormalities. Women with such abnormalities,most of whom were between 25 and 55 years old,included 479(3.46%)with atypical squamous cells(ASC)of unknown significance(ASC-US),25(0.18%) with atypical squamous cells that might correspond to high-grade squamous intraepithelial lesions(HSIL,ASC-H),235(1.70%)with low-grade squamous intraepithelial lesions(LSIL),90(0.65%)with HSIL,1(0.01%)with squamous cell carcinoma(SCC)and 4 (0.03%)with atypical glandular cells(AGC). The ratio of ASC to squamous intraepithelial lesions was 1.546. Cervical biopsy showed that 26 of the 27 women with HSIL had cervical intraepithelial neoplasia Ⅱ or Ⅲ. The diagnostic coincidence rate was 96.3%. Conclusion Cervical LCT can detect a large number of microbial infections and precancerous lesions,suggesting it is effective for cervical cancer screening of married women.

  3. The 12th Edition of the Scientific Days of the National Institute for Infectious Diseases “Prof. Dr. Matei Bals” and the 12th National Infectious Diseases Conference

    Directory of Open Access Journals (Sweden)

    Cristian-Mihail Niculae

    2016-11-01

    -positive patients admitted in the National Institute for Infectious Diseases “Prof. Dr. Matei Balș” in 2015 Mihaela Ionica, Ramona-Alexandra Zamfir, Alina Cozma, Otilia Elisabeta Benea A100 Title: Epidemiology of Candida oral infections (stomatitis in Romania Sergiu Fendrihan, Ecaterina Scortan, Mircea Ioan Popa A101 Anthrax case series in south-eastern Romania Corneliu P Popescu, Șerban N Benea, Andra E Petcu, Adriana Hristea, Adrian Abagiu, Iuliana A Podea, Raluca E Jipa, Georgeta Ducu, Raluca M Hrișcă, Dragoș Florea, Manuela Nica, Eliza Manea, Simona Merișor, Cristian M Nicolae, Simin A Florescu, Irina M Dumitru, Emanoil Ceaușu, Sorin Rugină, Ruxandra V Moroti A102 Knowledge, risk perception and attitudes of healthcare workers at the National Institute for Infectious Diseases “Prof. Dr. Matei Balș” regarding Ebola Daniela Pițigoi, Teodora Ionescu, Oana Săndulescu, Maria Nițescu, Bogdan Nițescu, Iulia Monica Mustaţă, Sorina Claudia Boldeanu, Florentina Furtunescu, Adrian Streinu-Cercel A103 A case of abdominopelvic actinomycosis with successful short-term antibiotic treatment Diana Gabriela Iacob, Simona Alexandra Iacob, Mihaela Gheorghe A104 A case of pneumonia caused by Raoultella planticola Iulian Diaconescu, Irina Niculescu, Floretina Dumitrescu, Lucian Giubelan A105 Vitamin D deficiency and sepsis in childhood Adriana Slavcovici, Raluca Tripon, Roxana Iubu, Cristian Marcu, Mihaela Sabou, Monica Muntean A106 The clinical and epidemiological aspects and prophylaxis of Lyme disease among patients who presented with tick bites to the Clinical Infectious Disease Hospital “Toma Ciorbă” Ion Chiriac, Tiberiu Holban, Liviu Tazlavanu A107 Drug-resistant tuberculosis in HIV infected patients Raluca Jipa, Eliza Manea, Roxana Cernat, Kezdi Iringo, Andrei Vâță, Manuela Arbune, Teodora Moisil, Adriana Hristea A108 Kidney injury molecule-1 and urinary tract infections Corina-Daniela Ene, Ilinca Nicolae, Roxana Simona Georgescu A109 The impact of