WorldWideScience

Sample records for actinium 224

  1. Dissolution processes. [224 references

    Energy Technology Data Exchange (ETDEWEB)

    Silver, G.L.

    1976-10-22

    This review contains more than 100 observations and 224 references on the dissolution phenomenon. The dissolution processes are grouped into three categories: methods of aqueous attack, fusion methods, and miscellaneous observations on phenomena related to dissolution problems. (DLC)

  2. Spectroscopic and computational investigation of actinium coordination chemistry

    Science.gov (United States)

    Ferrier, Maryline G.; Batista, Enrique R.; Berg, John M.; Birnbaum, Eva R.; Cross, Justin N.; Engle, Jonathan W.; La Pierre, Henry S.; Kozimor, Stosh A.; Lezama Pacheco, Juan S.; Stein, Benjamin W.; Stieber, S. Chantal E.; Wilson, Justin J.

    2016-08-01

    Actinium-225 is a promising isotope for targeted-α therapy. Unfortunately, progress in developing chelators for medicinal applications has been hindered by a limited understanding of actinium chemistry. This knowledge gap is primarily associated with handling actinium, as it is highly radioactive and in short supply. Hence, AcIII reactivity is often inferred from the lanthanides and minor actinides (that is, Am, Cm), with limited success. Here we overcome these challenges and characterize actinium in HCl solutions using X-ray absorption spectroscopy and molecular dynamics density functional theory. The Ac-Cl and Ac-OH2O distances are measured to be 2.95(3) and 2.59(3) Å, respectively. The X-ray absorption spectroscopy comparisons between AcIII and AmIII in HCl solutions indicate AcIII coordinates more inner-sphere Cl1- ligands (3.2+/-1.1) than AmIII (0.8+/-0.3). These results imply diverse reactivity for the +3 actinides and highlight the unexpected and unique AcIII chemical behaviour.

  3. Separation of Actinium 227 from the uranium minerals

    International Nuclear Information System (INIS)

    The purpose of this work was to separate Actinium 227, whose content is 18%, from the mineral carnotite found in Gomez Chihuahua mountain range in Mexico. The mineral before processing is is pre-concentrated and passed, first through anionic exchange resins, later the eluate obtained is passed through cationic resins. The resins were 20-50 MESH QOWEX and 100-200 MESH 50 X 8-20 in some cased 200-400 MESH AG 50W-X8, 1X8 in other cases. The eluates from the ionic exchange were electrodeposited on stainless steel polished disc cathode and platinum electrode as anode; under a current ODF 10mA for 2.5 to 5 hours and of 100mA for .5 of an hour. it was possible to identify the Actinium 227 by means of its descendents, TH-227 and RA-223, through alpha spectroscopy. Due to the radiochemical purity which the electro deposits were obtained the Actinium 227 was low and was not quantitatively determined. A large majority of the members of the natural radioactive series 3 were identified and even alpha energies reported in the literature with very low percentages of non-identified emissions were observed. We conclude that a more precise study is needed concerning ionic exchange and electrodeposit to obtain an Actinium 227 of radiochemical purity. (Author)

  4. Spectroscopic and computational investigation of actinium coordination chemistry

    Science.gov (United States)

    Ferrier, Maryline G.; Batista, Enrique R.; Berg, John M.; Birnbaum, Eva R.; Cross, Justin N.; Engle, Jonathan W.; La Pierre, Henry S.; Kozimor, Stosh A.; Lezama Pacheco, Juan S.; Stein, Benjamin W.; Stieber, S. Chantal E.; Wilson, Justin J.

    2016-01-01

    Actinium-225 is a promising isotope for targeted-α therapy. Unfortunately, progress in developing chelators for medicinal applications has been hindered by a limited understanding of actinium chemistry. This knowledge gap is primarily associated with handling actinium, as it is highly radioactive and in short supply. Hence, AcIII reactivity is often inferred from the lanthanides and minor actinides (that is, Am, Cm), with limited success. Here we overcome these challenges and characterize actinium in HCl solutions using X-ray absorption spectroscopy and molecular dynamics density functional theory. The Ac–Cl and Ac–OH2O distances are measured to be 2.95(3) and 2.59(3) Å, respectively. The X-ray absorption spectroscopy comparisons between AcIII and AmIII in HCl solutions indicate AcIII coordinates more inner-sphere Cl1– ligands (3.2±1.1) than AmIII (0.8±0.3). These results imply diverse reactivity for the +3 actinides and highlight the unexpected and unique AcIII chemical behaviour. PMID:27531582

  5. Discovery of the actinium, thorium, protactinium, and uranium isotopes

    CERN Document Server

    Fry, C

    2012-01-01

    Currently, 31 actinium, 31 thorium, 28 protactinium, and 23 uranium isotopes have so far been observed; the discovery of these isotopes is discussed. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.

  6. Spectroscopic and computational investigation of actinium coordination chemistry.

    Science.gov (United States)

    Ferrier, Maryline G; Batista, Enrique R; Berg, John M; Birnbaum, Eva R; Cross, Justin N; Engle, Jonathan W; La Pierre, Henry S; Kozimor, Stosh A; Lezama Pacheco, Juan S; Stein, Benjamin W; Stieber, S Chantal E; Wilson, Justin J

    2016-01-01

    Actinium-225 is a promising isotope for targeted-α therapy. Unfortunately, progress in developing chelators for medicinal applications has been hindered by a limited understanding of actinium chemistry. This knowledge gap is primarily associated with handling actinium, as it is highly radioactive and in short supply. Hence, Ac(III) reactivity is often inferred from the lanthanides and minor actinides (that is, Am, Cm), with limited success. Here we overcome these challenges and characterize actinium in HCl solutions using X-ray absorption spectroscopy and molecular dynamics density functional theory. The Ac-Cl and Ac-OH2O distances are measured to be 2.95(3) and 2.59(3) Å, respectively. The X-ray absorption spectroscopy comparisons between Ac(III) and Am(III) in HCl solutions indicate Ac(III) coordinates more inner-sphere Cl(1-) ligands (3.2±1.1) than Am(III) (0.8±0.3). These results imply diverse reactivity for the +3 actinides and highlight the unexpected and unique Ac(III) chemical behaviour. PMID:27531582

  7. 33 CFR 117.224 - Thames River.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Thames River. 117.224 Section 117.224 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Connecticut § 117.224 Thames River. The draw of the...

  8. 49 CFR 195.224 - Welding: Weather.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Welding: Weather. 195.224 Section 195.224 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY... PIPELINE Construction § 195.224 Welding: Weather. Welding must be protected from weather conditions...

  9. 22 CFR 224.34 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Evidence. 224.34 Section 224.34 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224... probative value is substantially outweighed by the danger of unfair prejudice, confusion of the issues,...

  10. 9 CFR 354.224 - Water supply.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Water supply. 354.224 Section 354.224....224 Water supply. The water supply shall be ample, clean, and potable with adequate facilities for its distribution in the plant and its protection against contamination and pollution. (a) Hot water at...

  11. 49 CFR 224.107 - Implementation schedule.

    Science.gov (United States)

    2010-10-01

    ... brake test as prescribed by 49 CFR 232.305. (ii) A freight rolling stock owner may elect not to follow... 49 Transportation 4 2010-10-01 2010-10-01 false Implementation schedule. 224.107 Section 224.107... Maintenance of Retroreflective Material § 224.107 Implementation schedule. (a) Railroad freight cars....

  12. Production of Actinium-225 via High Energy Proton Induced Spallation of Thorium-232

    International Nuclear Information System (INIS)

    The science of cancer research is currently expanding its use of alpha particle emitting radioisotopes. Coupled with the discovery and proliferation of molecular species that seek out and attach to tumors, new therapy and diagnostics are being developed to enhance the treatment of cancer and other diseases. This latest technology is commonly referred to as Alpha Immunotherapy (AIT). Actinium-225/Bismuth-213 is a parent/daughter alpha-emitting radioisotope pair that is highly sought after because of the potential for treating numerous diseases and its ability to be chemically compatible with many known and widely used carrier molecules (such as monoclonal antibodies and proteins/peptides). Unfortunately, the worldwide supply of actinium-225 is limited to about 1,000mCi annually and most of that is currently spoken for, thus limiting the ability of this radioisotope pair to enter into research and subsequently clinical trials. The route proposed herein utilizes high energy protons to produce actinium-225 via spallation of a thorium-232 target. As part of previous R and D efforts carried out at Argonne National Laboratory recently in support of the proposed US FRIB facility, it was shown that a very effective production mechanism for actinium-225 is spallation of thorium-232 by high energy proton beams. The base-line simulation for the production rate of actinium-225 by this reaction mechanism is 8E12 atoms per second at 200 MeV proton beam energy with 50 g/cm2 thorium target and 100 kW beam power. An irradiation of one actinium-225 half-life (10 days) produces ∼100 Ci of actinium-225. For a given beam current the reaction cross section increases slightly with energy to about 400 MeV and then decreases slightly for beam energies in the several GeV regime. The object of this effort is to refine the simulations at proton beam energies of 400 MeV and above up to about 8 GeV. Once completed, the simulations will be experimentally verified using 400 MeV and 8 GeV protons

  13. Production of Actinium-225 via High Energy Proton Induced Spallation of Thorium-232

    Energy Technology Data Exchange (ETDEWEB)

    Harvey, James T.; Nolen, Jerry; Vandergrift, George; Gomes, Itacil; Kroc, Tom; Horwitz, Phil; McAlister, Dan; Bowers, Del; Sullivan, Vivian; Greene, John

    2011-12-30

    The science of cancer research is currently expanding its use of alpha particle emitting radioisotopes. Coupled with the discovery and proliferation of molecular species that seek out and attach to tumors, new therapy and diagnostics are being developed to enhance the treatment of cancer and other diseases. This latest technology is commonly referred to as Alpha Immunotherapy (AIT). Actinium-225/Bismuth-213 is a parent/daughter alpha-emitting radioisotope pair that is highly sought after because of the potential for treating numerous diseases and its ability to be chemically compatible with many known and widely used carrier molecules (such as monoclonal antibodies and proteins/peptides). Unfortunately, the worldwide supply of actinium-225 is limited to about 1,000mCi annually and most of that is currently spoken for, thus limiting the ability of this radioisotope pair to enter into research and subsequently clinical trials. The route proposed herein utilizes high energy protons to produce actinium-225 via spallation of a thorium-232 target. As part of previous R and D efforts carried out at Argonne National Laboratory recently in support of the proposed US FRIB facility, it was shown that a very effective production mechanism for actinium-225 is spallation of thorium-232 by high energy proton beams. The base-line simulation for the production rate of actinium-225 by this reaction mechanism is 8E12 atoms per second at 200 MeV proton beam energy with 50 g/cm2 thorium target and 100 kW beam power. An irradiation of one actinium-225 half-life (10 days) produces {approx}100 Ci of actinium-225. For a given beam current the reaction cross section increases slightly with energy to about 400 MeV and then decreases slightly for beam energies in the several GeV regime. The object of this effort is to refine the simulations at proton beam energies of 400 MeV and above up to about 8 GeV. Once completed, the simulations will be experimentally verified using 400 MeV and 8 Ge

  14. Groundwater seepage from the Ranger uranium mine tailings dam: radioisotopes of radium, thorium and actinium. Supervising Scientist report 106

    International Nuclear Information System (INIS)

    Monitoring of bores near the Ranger uranium mine tailings dam has revealed deterioration in water quality in several bores since 1983. In a group of bores to the north of the dam, increases have been observed of up to 500 times for sulphate concentrations and of up to 5 times for 226Ra concentrations. Results are presented here of measurements of members of the uranium, thorium and actinium decay series in borewater samples collected between 1985 and 1993. In particular, measurements of all four naturally-occurring radium isotopes have been used in an investigation of the mechanism of radium concentration changes. For the most seepage-affected bores the major findings of the study include: 228Ra/226Ra 223Ra /226Ra and 224Ra/228Ra ratios all increased over the course of the study; barium concentrations show high seasonal variability, being lower in November than May, but strontium concentrations show a steady increase with time. Calculations show that the groundwater is probably saturated with respect to barite but not with respect to celestite or anglesite; sulphide concentrations are low in comparison with sulphate, and are higher in November than in May; and 227Ac concentrations have increased with time, but do not account for the high 223Ra/226Ra ratios. It is concluded on the basis of these observations that increases in Ra isotope concentrations observed in a number of seepage-affected bores arise from increases in salinity leading to desorption of radium from adsorption sites in the vicinity of the bore rather by direct transport of radium from the tailings. Increased salinity is also causing the observed increases in 227Ac and strontium concentrations, while formation of a barite solid phase in the groundwater is causing the removal of some radium from solution. This is the cause of the increasing radium isotope ratios noted above

  15. 7 CFR 1280.224 - Periodic evaluation.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Periodic evaluation. 1280.224 Section 1280.224 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE LAMB PROMOTION, RESEARCH,...

  16. 49 CFR 571.224 - Standard No. 224; Rear impact protection.

    Science.gov (United States)

    2010-10-01

    ... energy absorption requirement (S5.2.2) of 49 CFR 571.223. S4. Definitions. Chassis means the load... Motor Vehicle Safety Standards § 571.224 Standard No. 224; Rear impact protection. S1. Scope. This... the rear of trailers and semitrailers with a GVWR of 4,536 kg or more. S3. Application. This...

  17. Dicty_cDB: SSI224 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SS (Link to library) SSI224 (Link to dictyBase) - - - - SSI224Z (Link to Original site) - - SSI...las ID - NBRP ID - dictyBase ID - Link to Contig - Original site URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SS/SSI2-A/SSI...224Q.Seq.d/ Representative seq. ID SSI224Z (Link to Original site) R...DNA Score E Sequences producing significant alignments: (bits) Value SSI224 (SSI224Q) /CSM/SS/SSI2-A/SSI224Q...%: mitochondrial 8.0 %: cytoskeletal 4.0 %: vacuolar 4.0 %: vesicles of secretory system >> prediction for SSI

  18. Analysis of the gamma spectra of the uranium, actinium, and thorium decay series

    International Nuclear Information System (INIS)

    This report describes the identification of radionuclides in the uranium, actinium, and thorium series by analysis of gamma spectra in the energy range of 40 to 1400 keV. Energies and absolute efficiencies for each gamma line were measured by means of a high-resolution germanium detector and compared with those in the literature. A gamma spectroscopy method, which utilizes an on-line computer for deconvolution of spectra, search and identification of each line, and estimation of activity for each radionuclide, was used to analyze soil and uranium tailings, and ore

  19. 40 CFR 86.224-94 - Carbon dioxide analyzer calibration.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Carbon dioxide analyzer calibration. 86.224-94 Section 86.224-94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.224-94 Carbon...

  20. 22 CFR 224.5 - Review by the reviewing official.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Review by the reviewing official. 224.5 Section... REMEDIES ACT § 224.5 Review by the reviewing official. (a) If, based on the report of the investigating official under § 224.4(b), the reviewing official determines that there is adequate evidence to...

  1. 38 CFR 21.224 - Prevention of abuse.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Prevention of abuse. 21.224 Section 21.224 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED... Supplies § 21.224 Prevention of abuse. Supplies are to be furnished under the most careful checks by...

  2. Analysis of Radioactive Releases During Proposed Demolition Activities for the 224-U and 224-UA Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Napier, Bruce A.; Rishel, Jeremy P.; Droppo, James G.

    2009-03-31

    Atmospheric dispersion modeling has been conducted in support of the demolition of the 224-U and 224-UA buildings using estimated release rates to provide information on the location and levels of radioactive contamination that may be expected. The facilities surrounding the UO3 plant have the potential to affect dispersion patterns through various meteorological phenomena, including building wake effects. Hourly meteorological data collected over a 5-year period were used to examine the effects of wind speed, direction, and stability on projected concentrations of contaminants in air and deposited on nearby surfaces. The modeling results indicate that the radiological exposures from the planned demolition efforts will be below the designated limits for air and soil exposures.

  3. Thorium and actinium polyphosphonate compounds as bone-seeking alpha particle-emitting agents.

    Science.gov (United States)

    Henriksen, Gjermund; Bruland, Oyvind S; Larsen, Roy H

    2004-01-01

    The present study explores the use of alpha-particle-emitting, bone-seeking agents as candidates for targeted radiotherapy. Actinium and thorium 1,4,7,10 tetraazacyclododecane N,N',N'',N''' 1,4,7,10-tetra(methylene) phosphonic acid (DOTMP) and thorium-diethylene triamine N,N',N'' penta(methylene) phosphonic acid (DTMP) were prepared and their biodistribution evaluated in conventional Balb/C mice at four hours after injection. All three bone-seeking agents showed a high uptake in bone and a low uptake in soft tissues. Among the soft tissue organs, only kidney had a relatively high uptake. The femur/kidney ratios for 227Th-DTMP, 228-Ac-DOTMP and 227Th-DOTMP were 14.2, 7.6 and 6.0, respectively. A higher liver uptake of 228Ac-DOTMP was seen than for 227Th-DTMP and 227Th-DOTMP. This suggests that some demetallation of the 228Ac-DOTMP complex had occurred. The results indicate that 225Ac-DOTMP, 227Th-DOTMP and 227Th-DTMP have promising properties as potential therapeutic bone-seeking agents.

  4. Developments towards in-gas-jet laser spectroscopy studies of actinium isotopes at LISOL

    Science.gov (United States)

    Raeder, S.; Bastin, B.; Block, M.; Creemers, P.; Delahaye, P.; Ferrer, R.; Fléchard, X.; Franchoo, S.; Ghys, L.; Gaffney, L. P.; Granados, C.; Heinke, R.; Hijazi, L.; Huyse, M.; Kron, T.; Kudryavtsev, Yu.; Laatiaoui, M.; Lecesne, N.; Luton, F.; Moore, I. D.; Martinez, Y.; Mogilevskiy, E.; Naubereit, P.; Piot, J.; Rothe, S.; Savajols, H.; Sels, S.; Sonnenschein, V.; Traykov, E.; Van Beveren, C.; Van den Bergh, P.; Van Duppen, P.; Wendt, K.; Zadvornaya, A.

    2016-06-01

    To study exotic nuclides at the borders of stability with laser ionization and spectroscopy techniques, highest efficiencies in combination with a high spectral resolution are required. These usually opposing requirements are reconciled by applying the in-gas-laser ionization and spectroscopy (IGLIS) technique in the supersonic gas jet produced by a de Laval nozzle installed at the exit of the stopping gas cell. Carrying out laser ionization in the low-temperature and low density supersonic gas jet eliminates pressure broadening, which will significantly improve the spectral resolution. This article presents the required modifications at the Leuven Isotope Separator On-Line (LISOL) facility that are needed for the first on-line studies of in-gas-jet laser spectroscopy. Different geometries for the gas outlet and extraction ion guides have been tested for their performance regarding the acceptance of laser ionized species as well as for their differential pumping capacities. The specifications and performance of the temporarily installed high repetition rate laser system, including a narrow bandwidth injection-locked Ti:sapphire laser, are discussed and first preliminary results on neutron-deficient actinium isotopes are presented indicating the high capability of this novel technique.

  5. 14 CFR 125.224 - Collision avoidance system.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Collision avoidance system. 125.224 Section... Requirements § 125.224 Collision avoidance system. Effective January 1, 2005, any airplane you operate under this part 125 must be equipped and operated according to the following table: Collision...

  6. 48 CFR 52.224-2 - Privacy Act.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Privacy Act. 52.224-2... AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 52.224-2 Privacy... agency function: Privacy Act (APR 1984) (a) The Contractor agrees to— (1) Comply with the Privacy Act...

  7. 48 CFR 352.224-70 - Privacy Act.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Privacy Act. 352.224-70... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 352.224-70 Privacy Act. As prescribed in 324.103(b)(2), the Contracting Officer shall insert the following clause: Privacy Act...

  8. 14 CFR 417.224 - Probability of failure analysis.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Probability of failure analysis. 417.224..., DEPARTMENT OF TRANSPORTATION LICENSING LAUNCH SAFETY Flight Safety Analysis § 417.224 Probability of failure..., must account for launch vehicle failure probability in a consistent manner. A launch vehicle...

  9. Iron status markers in 224 indigenous Greenlanders

    DEFF Research Database (Denmark)

    Milman, N; Byg, K E; Mulvad, G;

    2001-01-01

    OBJECTIVE: To evaluate iron status in indigenous Greenlanders and its relationship to gender, age and intake of traditional Greenlandic foods. Methods: Serum ferritin, serum transferrin saturation and haemoglobin were evaluated in a population survey in 1993-1994 comprising 224 Greenlandic...... of iron deficiency anaemia (ferritin iron-replete men and women) was 0.92% in men and 0.87% in women. Correlations between age and ferritin were lowest in Nuuk (men, r(s)=0.26, p=0.2; women, r(s)=0.50, p=0.001) intermediary in Ilulissat (men, r(s)=0.37, p=0...... ferritin levels were lowest in Nuuk (men, 92 microg/L; women, 40 microg/L), higher in Ilulissat (men, 104 microg/L; women, 69 microg/L) and in Uummannaq (men, 118 microg/L; women, 46 microg/L) (piron load (ferritin >200 microg/L) was lowest in Nuuk (men: 13.8%, women: 2...

  10. Distribution of radium-224 in the western Arctic Ocean

    Institute of Scientific and Technical Information of China (English)

    QIU Yusheng; CHEN Min; LI Yanping

    2005-01-01

    Radium-224 activities in the western Arctic Ocean were measured via ship-board 220Rn emanation technique during the Second Chinese National Arctic Expedition. The results showed that the 224Ra activities in the study areas ranged from being less than 0.08 to 3.58 Bq/m3, with an average of 0.23 Bq/m3. The low 224Ra concentration in the surface water was attributed to the influence of sea ice melted water. The horizontal distribution of surface 224Ra in the western Arctic Ocean showed a high 224Ra characteristics occurred along the slope around 160°W, providing evidence for the importance of ice-rafted sediments to controlling the distribution of radium isotopes in the Arctic Ocean. Mostly, 224Ra concentrations increased with the depth in the shelf region and reached a maximum at 75 m at the central Canada Basin, which further confirms the importance of the transport of shelf bottom water to maintaining the upper halocline layer in the Canada Basin.

  11. Argonne-Utah studies of 224Ra endosteal surface dosimetry

    International Nuclear Information System (INIS)

    The activities of 212Pb relative to 224Ra and of 222Rn relative to 226Ra were measured in bone surface deposits 24 h after injection of radium into beagles. The fractional retention of 220Rn atoms was measured in vitro with hydrated and dehydrated bone samples to determine the effect of water content on the escape of radon from bone surfaces. The experimental data suggest that substantial 224Ra daughter-product disequilibrium exists in bone surface deposits. Estimates for the lower and upper limits on the fractional retention of 220Rn in vivo are 0.05 and 0.25, respectively. The average bone surface activity of 212Pb relative to 224Ra ranged from 0.34 to 0.71 for four dogs, with the majority of the values toward the lower end of the range. Only a small portion of the deposited 212Pb came from lead in the injection solution despite near equilibrium between 224Ra and its daughters at the time of injection. The retention data indicate that the endosteal tissue dose rate in the dogs at one day was actually one-third to about one-half that which would be calculated assuming equilibrium of 224Ra daughter products in bone surface deposits. 11 references, 2 figures, 7 tables

  12. Structural integrity analysis of the 224U elevator mothballing

    International Nuclear Information System (INIS)

    As part of the preparation of Building 224U for turnover to Decontamination and Decommissioning, it is necessary to place the elevator in a mothballed condition so that it can be reactivated for use after 10 to 25 years. This mothballing is going to be accomplished by landing the counterweight on wooden timbers and suspending the elevator cab with wire rope or chain slings. This will take the load off the cables and make it relatively easy to reactive. The objective of this Supporting Document is to verify the structural integrity of all of the load bearing components involved in mothballing the 224U Building elevator. Building 224U is part of the UO3 Plant where uranyl nitrates from the PUREX Plant was converted to UO3 powder

  13. The biological effects of 224Ra injected into dogs

    International Nuclear Information System (INIS)

    The purpose of this study was to investigate the toxicity of injected 224Ra in the dog. Radium-224 is a short-lived isotope of radium with a half-life of 3.62 d. When administered parenterally, it deposits on bone surfaces; because of its short half-life, most of its energy is deposited on bone surfaces, in a manner similar to plutonium. The experimental design included a comparison to the exposed human population. Instead of using a single injection of 224Ra, groups were included in which dogs were injected once, 10 times, or 50 times. This design provided groups that could be compared to the multiple injections often used in people for the treatment of ankylosing spondylitis

  14. DF-224 Version 7.3 FS Installation

    Science.gov (United States)

    Boyce, Leslye

    1990-12-01

    Version 7.3 will implement a three logical memory unit contingency plan. It removes under utilized DF-224 code to recover memory margins and restructures code. The installation of DF-224, version 7.3 will be broken into a Installation, Regression test, and Contingency Back-out time. In addition, it eliminates the 10 and 300 second processing rate. It is highly desirable to implement the version of the flight software ASAP. Due to the complexity of the installation, dedicated spacecraft time is required to minimize spacecraft risk In summary, this proposal requests 14 orbits of dedicated spacecraft time for installation, regression test, and contingency back_out time for DF-224 FS V7.3 to be scheduled in the first few days of SMS 054.

  15. Reflection asymmetry in odd-A and odd-odd actinium nuclei

    International Nuclear Information System (INIS)

    Theoretical calculations and measurements indicate that octupole correlations are at a maximum in the ground states of the odd-proton nuclei Ac and Pa. It has been expected that odd-odd nuclei should have even larger amount of octupole-octupole correlations. We have recently made measurements on the structure of 224Ac. Although spin and parity assignments could not be made, two bands starting at 354.1 and 360.0 keV have properties characteristic of reflection asymmetric shape. These two bands have very similar rotational constants and also similar alpha decay rates, which suggest similarity between the wavefunctions of these bands. These signatures provide evidence for octupole correlations in these nuclides

  16. 47 CFR 36.224 - Extraordinary items-Account 7600.

    Science.gov (United States)

    2010-10-01

    ... Income Accounts Certain Income Accounts § 36.224 Extraordinary items—Account 7600. (a) Amounts in this account of an operating nature are apportioned on a basis consistent with the nature of these items. ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Extraordinary items-Account 7600....

  17. DF-224 Version 8.0 FS Installation

    Science.gov (United States)

    Boyce, Leslye

    1990-12-01

    DF-224 Version 8.0 will implement the final phase of the 3 Logical Memory Unit Contingency Plan described in LMSC,EM SPS640. It focuses on new capabilities, implementing a spin stabilized safemode, correcting the integral calculation in Momentum Management Law and other miscellaneous command changes geared at enhancing acquistions and science. Due to the complexity of the installation, dedicated space-craft time is required to minimize risk. In summary, this proposal requests 7 orbits of dedicated spacecraft time for installation, regression testing and contingency back-out time for DF-224 Flight Software (FS) Version 8.0 for the week of April 27,(SMS118). No dedicated time is requested for the pre-load of the FS.

  18. Treatment of ankylosing spondylitis with [{sup 224}Ra]-Radiumchloride; Therapie der Spondylitis ankylosans mit [{sup 224}Ra]-Radiumchlorid

    Energy Technology Data Exchange (ETDEWEB)

    Reiners, C. [Klinik und Poliklinik fuer Nuklearmedizin der Univ. Wuerzburg (Germany); Braun, J. [Rheumazentrum Ruhrgebiet Herne (Germany)

    2001-07-01

    Ankylosing spondylitis (AS) is a chronic disease which in 30-50% of the patients leads to considerable episodes of pain, a remarkable reduction of quality of life and disablement. For treatment mostly nonsteroidal antiphlogistic drugs are used which are able to reduce pain in approximately 80% of the patients only. Those drugs however, have to be withdrawn in approximately 30% of the patients due to its known toxicity (mainly in the gastrointestinal tract). Basis medication (DMARDs) is helpful in a minority of AS patients only. Recently [{sup 224}Ra]-Radiumchloride, which has been used previously between 1955 and 1990, has been made available again for treatment of AS. Whereas biokinetics, radiation exposure and the risk-profile of [{sup 224}Ra]-Radiumchloride are documented well by experimental and clinical data, most of the historical studies about the efficacy of this radiopharmaceutical do not fulfill the requirements of modern therapy studies. Therefore as many patients as possible should be recruited for a prospective long-time Phase IV study. A close and well-coordinated cooperation between rheumatologists and nuclear medicine physicians is needed, when [{sup 224}Ra]-Radiumchloride is used for treatment of AS. (orig.) [German] Die meist chronisch, oft auch in Schueben verlaufende Spondylitis ankylosans (AS) fuehrt bei 30-50% der Patienten zu betraechtlichen Schmerzen und einer nicht selten erheblichen Einschraenkung der Lebensqualitaet und Behinderung. Die am haeufigsten zur Therapie verwendeten nichtsteroidalen Antiphlogistika koennen nur bei etwa 80% der Patienten die Schmerzen lindern. Allerdings muessen diese Medikamente bei 20-30% der AS-Patienten wegen ihrer bekannten Toxizitaet - vor allem im Gastrointestinaltrakt - abgesetzt werden. Basistherapeutika (DMARDs) helfen bei der AS nur sehr begrenzt. Mit [{sup 224}Ra]-Radiumchlorid steht seit kurzem ein bereits in den Jahren 1945-1990 fuer die Behandlung der AS verwendetes Radiopharmakon wieder zur

  19. Fine structure in the alpha decay of {sup 224} U

    Energy Technology Data Exchange (ETDEWEB)

    Lopez-Martens, A.; Hauschild, K.; Rezynkina, K. [CNRS-IN2P3, CSNSM, Universite Paris Sud, Orsay (France); Dorvaux, O.; Gall, B.; Dechery, F.; Faure, H. [CNRS-IN2P3, IPHC, Universite de Strasbourg, Strasbourg (France); Yeremin, A.V.; Chelnokov, M.L.; Chepigin, V.I.; Isaev, A.V.; Izosimov, I.N.; Katrasev, D.E.; Kuznetsov, A.N.; Kuznetsova, A.A.; Malyshev, O.N.; Popeko, A.G.; Sokol, E.A.; Svirikhin, A.I. [JINR, FLNR, Dubna (Russian Federation); Piot, J. [CNRS-IN2P3, GANIL, CEA-DSM, Caen (France); Rubert, J. [CNRS-IN2P3, IPHC, Universite de Strasbourg, Strasbourg (France); CNRS-IN2P3, LPSC, Universite Grenoble-Alpes, Grenoble (France)

    2014-08-15

    {sup 224}U nuclei were populated in fusion-evaporation reactions using a {sup 206}Pb target and an intense {sup 22}Ne beam. Fusion-evaporation residues were separated by the new separator SHELS at the FLNR, Dubna and implanted into a large-area double-sided silicon strip detector. Position- and time-correlated alpha decays were used to identify evaporation residues. A new α -decay line at 8095(11) keV was observed in this work and assigned as the decay from {sup 224}U to the first excited 2{sup +} in the daughter nucleus {sup 220}Th. Coincident photons were also observed allowing to unambiguously determine the excitation energy of the first excited 2{sup +} state in {sup 220}Th to be 386.5(1) keV and not 373.3(1)keV as previously reported. The half-life of {sup 224}U was measured to be 396(17)μs. (orig.)

  20. 42 CFR 436.224 - Individuals under age 21 who are under State adoption assistance agreements.

    Science.gov (United States)

    2010-10-01

    ... assistance agency determines that— (i) At the time of the adoption placement, the child had special needs for... adoption assistance agreements. 436.224 Section 436.224 Public Health CENTERS FOR MEDICARE & MEDICAID....224 Individuals under age 21 who are under State adoption assistance agreements. (a) The agency...

  1. 77 FR 71474 - Seventeenth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Science.gov (United States)

    2012-11-30

    ...). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security Access Control Systems. SUMMARY... Committee 224, Airport Security Access Control Systems. DATES: The meeting will be held December 13, 2012... Federal Aviation Administration Seventeenth Meeting: RTCA Special Committee 224, Airport Security...

  2. 78 FR 43963 - Twenty-Third Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Science.gov (United States)

    2013-07-22

    ...). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security Access Control Systems. SUMMARY... Committee 224, Airport Security Access Control Systems. DATES: The meeting will be held on June 20, 2013... Federal Aviation Administration Twenty-Third Meeting: RTCA Special Committee 224, Airport Security...

  3. 77 FR 64838 - Sixteenth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Science.gov (United States)

    2012-10-23

    ...). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security Access Control Systems. SUMMARY... Committee 224, Airport Security Access Control Systems. DATES: The meeting will be held November 15, 2012... Federal Aviation Administration Sixteenth Meeting: RTCA Special Committee 224, Airport Security...

  4. 78 FR 16757 - Twentieth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Science.gov (United States)

    2013-03-18

    ...). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security Access Control Systems. SUMMARY... Committee 224, Airport Security Access Control Systems. DATES: The meeting will be held April 4, 2013 from 9... Federal Aviation Administration Twentieth Meeting: RTCA Special Committee 224, Airport Security...

  5. 78 FR 31627 - Twenty-Second Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Science.gov (United States)

    2013-05-24

    ...). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security Access Control Systems. SUMMARY... Committee 224, Airport Security Access Control Systems. DATES: The meeting will be held on June 20, 2013... Federal Aviation Administration Twenty-Second Meeting: RTCA Special Committee 224, Airport Security...

  6. 78 FR 7850 - Nineteenth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Science.gov (United States)

    2013-02-04

    ...). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security Access Control Systems. SUMMARY... Committee 224, Airport Security Access Control Systems. DATES: The meeting will be held February 21, 2013... Federal Aviation Administration Nineteenth Meeting: RTCA Special Committee 224, Airport Security...

  7. 77 FR 55894 - Fifteenth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Science.gov (United States)

    2012-09-11

    ...). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security Access Control Systems. SUMMARY... Committee 224, Airport Security Access Control Systems DATES: The meeting will be held September 27-28, 2012... Federal Aviation Administration Fifteenth Meeting: RTCA Special Committee 224, Airport Security...

  8. 78 FR 22025 - Twenty First Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Science.gov (United States)

    2013-04-12

    ...). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security Access Control Systems. SUMMARY... Committee 224, Airport Security Access Control Systems. DATES: The meeting will be held April 9-10, 2013... Federal Aviation Administration Twenty First Meeting: RTCA Special Committee 224, Airport Security...

  9. 50 CFR 224.105 - Speed restrictions to protect North Atlantic Right Whales.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Speed restrictions to protect North Atlantic Right Whales. 224.105 Section 224.105 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE... AND ANADROMOUS SPECIES § 224.105 Speed restrictions to protect North Atlantic Right Whales. (a)...

  10. Malignancies in patients treated with high doses of radium-224

    Energy Technology Data Exchange (ETDEWEB)

    Nekolla, E.A. [Federal Office for Radiation Protection (BfS), Neuherberg (Germany); Walsh, L. [Radiobiological Inst., Univ. of Munich (Germany); Schottenhammer, G.; Spiess, H. [Children' s Hospital, Univ. of Munich (Germany)

    2005-07-01

    Several thousand German patients suffering from ankylosing spondylitis, tuberculosis and some other diseases, received multiple injections of the short-lived {alpha}-emitter {sup 224}Ra. The ''Spiess study'' was initiated in the early 1950s to follow the health of 899 persons (278 female, 621 male) who were treated mainly between 1945 and 1955. Most of the high dose patients and nearly all of those treated as children or juveniles (n=217) were included in the study. In June 2003, 152 persons were still alive. The most striking observed health effect, following {sup 224}Ra injections, was a temporal wave of 56 malignant bone tumours with a maximum at about 8 years after exposure which has already been described in several publications. In 2000, a new analysis was performed because an improved dosimetry resulted in modified bone surface doses. The estimated risk coefficient, averaged over all ages at exposure, was found to be in agreement with earlier analyses. However, a statistically significant increase of bone tumour risk with decreasing age at exposure was found. The earlier results, which indicated a reversed protraction factor, were confirmed. A significant excess of non-skeletal solid malignancies has also appeared during the most recent observation decade. In 2004, significant increases of cancer rates were observed for several sites: for breast cancer (31 cases observed vs. 9.1 cases expected), soft tissue malignancies (11 vs. 1.0), thyroid carcinomas (7 vs. 0.9), liver (8 vs. 2.3), kidney (13 vs. 4.6), pancreas (8 vs. 3.9), and bladder cancer (14 vs. 7.7). The 8-fold excess relative risk of mammary cancers in those women exposed as children or juveniles is particularly striking; moreover, 2 cases of breast cancer occurred in men. In 1993, a control group of tuberculosis patients not treated with {sup 224}Ra was established to rule out potential confounding factors - such as chest fluoroscopy - which might bias the breast cancer excess

  11. Malignancies in patients treated with high doses of radium-224

    International Nuclear Information System (INIS)

    Several thousand German patients suffering from ankylosing spondylitis, tuberculosis and some other diseases, received multiple injections of the short-lived α-emitter 224Ra. The ''Spiess study'' was initiated in the early 1950s to follow the health of 899 persons (278 female, 621 male) who were treated mainly between 1945 and 1955. Most of the high dose patients and nearly all of those treated as children or juveniles (n=217) were included in the study. In June 2003, 152 persons were still alive. The most striking observed health effect, following 224Ra injections, was a temporal wave of 56 malignant bone tumours with a maximum at about 8 years after exposure which has already been described in several publications. In 2000, a new analysis was performed because an improved dosimetry resulted in modified bone surface doses. The estimated risk coefficient, averaged over all ages at exposure, was found to be in agreement with earlier analyses. However, a statistically significant increase of bone tumour risk with decreasing age at exposure was found. The earlier results, which indicated a reversed protraction factor, were confirmed. A significant excess of non-skeletal solid malignancies has also appeared during the most recent observation decade. In 2004, significant increases of cancer rates were observed for several sites: for breast cancer (31 cases observed vs. 9.1 cases expected), soft tissue malignancies (11 vs. 1.0), thyroid carcinomas (7 vs. 0.9), liver (8 vs. 2.3), kidney (13 vs. 4.6), pancreas (8 vs. 3.9), and bladder cancer (14 vs. 7.7). The 8-fold excess relative risk of mammary cancers in those women exposed as children or juveniles is particularly striking; moreover, 2 cases of breast cancer occurred in men. In 1993, a control group of tuberculosis patients not treated with 224Ra was established to rule out potential confounding factors - such as chest fluoroscopy - which might bias the breast cancer excess. From the comparison it appeared, that the

  12. Bedside etiology of childhood cancer. [X radiation, /sup 224/Ra

    Energy Technology Data Exchange (ETDEWEB)

    Miller, R.W.

    1977-01-01

    The following topics are discussed: adenocarcinomas of the vagina in young women exposed prenatally to diethylstilbestrol; neuroblastoma in children exposed prenatally to hydantoin; increased frequency of leukemia in Japanese children surviving the atomic bomb; cancer in adults following administration of /sup 224/Ra during childhood; increased risk of lung cancer following environmental exposure of children to asbestos; lung cancer in adults following exposure to lead, copper, zinc, and arsenic; association of chromosomal aberrations with leukemia in children exposed to x radiation and benzene; immunosuppression in lymphoma patients; renal dysplasia in patients with Wilms' tumor; and aggregation of neoplasms in families. (HLW)

  13. Epidemiological studies of German patients injected with Ra-224

    International Nuclear Information System (INIS)

    The health of 898 patients who received repeated injections of short-lived 224Ra after World War II, mainly for the treatment of tuberculosis and ankylosing spondylitis has been followed. As of 1980, 53 of these patients had developed bone sarcoma vs only 0.2 cases expected naturally. Two patients with bone sarcoma subsequently developed an additional bone sarcoma. No new bone sarcomas have been reported since the end of 1974. For the patients in each category, the tumor rate at every year after 224Ra injection was calculated by dividing the yearly number of bone sarcomas by the number of patients whose follow-up extended to that year. This corrected for the effects of death and incomplete follow-up. The yearly tumor rates were then summed to obtain the cumulative tumor rate. Dividing by the average skeletal dose in rads yielded the cumulative risk. The cumulative tumor risk was about 200 bone sarcomas/106 person rad of average skeletal dose and, with the dosimetric assumptions used, was not statistically different for (a) juveniles vs adults, (b) males vs females, or (c) TB patients vs spondylitic patients

  14. Octupole collectivity in $^{220}$Rn and $^{224}$Ra

    CERN Document Server

    Gaffney, Liam Paul

    Collective properties of the radioactive nuclei $^{220}$Rn and $^{224}$Ra have been studied via Coulomb excitation of a 2.8$\\,$A.MeV radioactive ion beam (RIB) incident upon $^{60}$Ni, $^{112,114}$Cd and $^{120}$Sn targets. The experiments took place at the REX-ISOLDE RIB facility, CERN. De-excitation $\\gamma$-ray yields following multiple-step Coulomb excitation were detected in coincidence with recoiling target nuclei in the Miniball spectrometer. For the first time, B(E3;3$^+ \\rightarrow 0^+$) values have been directly measured with a radioactive ion beam. In the process, $^{224}$Ra becomes the heaviest post-accelerated RIB to date at ISOLDE (with the possible exception of the quasi-stable $^{238}$U). The measurements presented in this thesis represent a tripling of the number of nuclei around Z$\\simeq88$ and N$\\simeq134$, for which direct measurements of the octupole collectivity have been performed. The only previous measurements being for the relatively long-lived $^{226}$Ra. The $\\gamma$-ray yields, in...

  15. Isolation and characterization of Bradyrhizobium sp. 224 capable of degrading sulfanilic acid.

    Science.gov (United States)

    Hayase, Nobuki; Fujikawa, Yui; Nakagawa, Katsuhiko; Ushio, Kazutoshi

    2016-08-01

    A bacterial strain (strain 224), which has the ability to utilize sulfanilic acid as a sole source of carbon, was isolated from soil. 16S rRNA gene sequence obtained from strain 224 exhibited 100% identical to that of species in the genus Bradyrhizobium. Strain 224 degraded 4.7 mM of sulfanilic acid and released almost the same molar concentration of sulfate ion.

  16. MiR-224 expression increases radiation sensitivity of glioblastoma cells

    International Nuclear Information System (INIS)

    Highlights: • MiR-224 expression in established glioblastoma cell lines and sporadic tumor tissues is low. • Exogenous miR-224 expression was found to increase radiation sensitivity of glioblastoma cells. • MiR-224 expression brought about 55–60% reduction in API5 expression levels. • Transfection with API5 siRNA increased radiation sensitivity of glioblastoma cells. • Low miR-224 and high API5 expression correlated with worse survival of GBM patients. - Abstract: Glioblastoma (GBM) is the most common and highly aggressive primary malignant brain tumor. The intrinsic resistance of this brain tumor limits the efficacy of administered treatment like radiation therapy. In the present study, effect of miR-224 expression on growth characteristics of established GBM cell lines was analyzed. MiR-224 expression in the cell lines as well as in primary GBM tumor tissues was found to be low. Exogenous transient expression of miR-224 using either synthetic mimics or stable inducible expression using doxycycline inducible lentiviral vector carrying miR-224 gene, was found to bring about 30–55% reduction in clonogenic potential of U87 MG cells. MiR-224 expression reduced clonogenic potential of U87 MG cells by 85–90% on irradiation at a dose of 6 Gy, a dose that brought about 50% reduction in clonogenic potential in the absence of miR-224 expression. MiR-224 expression in glioblastoma cells resulted in 55–65% reduction in the expression levels of API5 gene, a known target of miR-224. Further, siRNA mediated down-regulation of API5 was also found to have radiation sensitizing effect on glioblastoma cell lines. Analysis of the Cancer Genome Atlas data showed lower miR-224 expression levels in male GBM patients to correlate with poorer survival. Higher expression levels of miR-224 target API5 also showed significant correlation with poorer survival of GBM patients. Up-regulation of miR-224 or down-regulation of its target API5 in combination with radiation therapy

  17. MiR-224 expression increases radiation sensitivity of glioblastoma cells

    Energy Technology Data Exchange (ETDEWEB)

    Upraity, Shailendra; Kazi, Sadaf; Padul, Vijay; Shirsat, Neelam Vishwanath, E-mail: nshirsat@actrec.gov.in

    2014-05-30

    Highlights: • MiR-224 expression in established glioblastoma cell lines and sporadic tumor tissues is low. • Exogenous miR-224 expression was found to increase radiation sensitivity of glioblastoma cells. • MiR-224 expression brought about 55–60% reduction in API5 expression levels. • Transfection with API5 siRNA increased radiation sensitivity of glioblastoma cells. • Low miR-224 and high API5 expression correlated with worse survival of GBM patients. - Abstract: Glioblastoma (GBM) is the most common and highly aggressive primary malignant brain tumor. The intrinsic resistance of this brain tumor limits the efficacy of administered treatment like radiation therapy. In the present study, effect of miR-224 expression on growth characteristics of established GBM cell lines was analyzed. MiR-224 expression in the cell lines as well as in primary GBM tumor tissues was found to be low. Exogenous transient expression of miR-224 using either synthetic mimics or stable inducible expression using doxycycline inducible lentiviral vector carrying miR-224 gene, was found to bring about 30–55% reduction in clonogenic potential of U87 MG cells. MiR-224 expression reduced clonogenic potential of U87 MG cells by 85–90% on irradiation at a dose of 6 Gy, a dose that brought about 50% reduction in clonogenic potential in the absence of miR-224 expression. MiR-224 expression in glioblastoma cells resulted in 55–65% reduction in the expression levels of API5 gene, a known target of miR-224. Further, siRNA mediated down-regulation of API5 was also found to have radiation sensitizing effect on glioblastoma cell lines. Analysis of the Cancer Genome Atlas data showed lower miR-224 expression levels in male GBM patients to correlate with poorer survival. Higher expression levels of miR-224 target API5 also showed significant correlation with poorer survival of GBM patients. Up-regulation of miR-224 or down-regulation of its target API5 in combination with radiation therapy

  18. 50 CFR 224.103 - Special prohibitions for endangered marine mammals.

    Science.gov (United States)

    2010-10-01

    ... regulations at 36 CFR 13.65 that pertain specifically to the waters of Glacier Bay National Park and Preserve... mammals. 224.103 Section 224.103 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS ENDANGERED MARINE...

  19. 25 CFR 224.85 - When may a tribe enter into a lease or business agreement?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false When may a tribe enter into a lease or business agreement? 224.85 Section 224.85 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION...

  20. 22 CFR 224.26 - Form, filing and service of papers.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Form, filing and service of papers. 224.26... CIVIL REMEDIES ACT § 224.26 Form, filing and service of papers. (a) Form. (1) Documents filed with the ALJ shall include an original and two copies. (2) Every pleading and paper filed in the...

  1. 78 FR 51810 - Twenty-Fourth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Science.gov (United States)

    2013-08-21

    ... Security Access Control Systems AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security Access Control... RTCA Special Committee 224, Airport Security Access Control Systems. DATES: The meeting will be held...

  2. 77 FR 25525 - Thirteenth Meeting: RTCA Special Committee 224, Airport Security Access Control Systems.

    Science.gov (United States)

    2012-04-30

    ... Access Control Systems. AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Meeting Notice of RTCA Special Committee 224, Airport Security Access Control Systems... Committee 224, Airport Security Access Control Systems DATES: The meeting will be held May 30, 2012, from...

  3. 42 CFR 457.224 - FFP: Conditions relating to cost sharing.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false FFP: Conditions relating to cost sharing. 457.224... Claims; Reduction of Federal Medical Payments § 457.224 FFP: Conditions relating to cost sharing. (a) No FFP is available for the following amounts, even when related to services or benefit coverage which...

  4. 50 CFR 224.104 - Special requirements for fishing activities to protect endangered sea turtles.

    Science.gov (United States)

    2010-10-01

    ... activities to protect endangered sea turtles. 224.104 Section 224.104 Wildlife and Fisheries NATIONAL MARINE... endangered sea turtles. (a) Shrimp fishermen in the southeastern United States and the Gulf of Mexico who comply with rules for threatened sea turtles specified in § 223.206 of this chapter will not be...

  5. MicroRNA-224 targets ERG2 and contributes to malignant progressions of meningioma

    International Nuclear Information System (INIS)

    MicroRNA-224 is overexpressed in various malignant tumors with poor prognosis, which plays a critical role in biological processes including cell proliferation, apoptosis and several developmental and physiological progressions. However, the potential association between miR-224 and clinical outcome in patients with meningiomas remains unknown. Here, we investigate miR-224 expression and biological functions in meningiomas. MiR-224 expression was measured by Northern blot analysis and quantitative reverse transcription-polymerase chain reaction (qRT-PCR) in meningioma and normal brain tissues. Kaplan–Meier analysis and Cox regression analysis were used to exam its correlation with clinicopathological features and prognostic value. The biological effects of miR-224 on the cell proliferation and apoptosis in meningioma cells were examined by MTT assay and apoptosis assay. We found the expression levels of miR-224 were significantly higher in meningioma tissues than that in normal brain, positively correlated with advanced pathological grade. Kaplan–Meier analysis indicated that meningioma patients with low miR-224 expression exhibited significantly prolonged overall and recurrence-free survival. Furthermore, we demonstrated that ERG2 was an identical candidate target gene of MiR-224 in vitro. Our results indicated that downregulation of miR-224 suppressed cell growth and resulted in the enhancement of cell apoptosis through activation of the ERG2-BAK-induced apoptosis pathway. Our findings imply the miR-224 expression could predict the overall survival and recurrence-free survival of patients with meningioma and it might be a promising therapeutic target for treating malignant meningiomas. - Highlights: • MiR-224 expression is correlates with prognosis in meningioma patients. • ERG2 is a novel downstream target of miR-224. • MiR-224 suppressed cell growth and enhanced apoptosis in IOMM-Lee and CH157 cells. • MiR-224 is an upstream regulator of the ERG2

  6. MicroRNA-224 targets ERG2 and contributes to malignant progressions of meningioma

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Maomao; Deng, Xiaodong; Ying, Qi; Jin, Tingyan [The 411 Hospital of PLA, Department of Neurosurgery, 15 Dongjiangwan Road, Shanghai 200081 (China); Li, Ming [The 81 Hospital of PLA, Department of Neurosurgery, 34 Taiping Road, Nanjing 210002 (China); Liang, Chong, E-mail: liangchong1984@163.com [The 81 Hospital of PLA, Department of Neurosurgery, 34 Taiping Road, Nanjing 210002 (China)

    2015-05-01

    MicroRNA-224 is overexpressed in various malignant tumors with poor prognosis, which plays a critical role in biological processes including cell proliferation, apoptosis and several developmental and physiological progressions. However, the potential association between miR-224 and clinical outcome in patients with meningiomas remains unknown. Here, we investigate miR-224 expression and biological functions in meningiomas. MiR-224 expression was measured by Northern blot analysis and quantitative reverse transcription-polymerase chain reaction (qRT-PCR) in meningioma and normal brain tissues. Kaplan–Meier analysis and Cox regression analysis were used to exam its correlation with clinicopathological features and prognostic value. The biological effects of miR-224 on the cell proliferation and apoptosis in meningioma cells were examined by MTT assay and apoptosis assay. We found the expression levels of miR-224 were significantly higher in meningioma tissues than that in normal brain, positively correlated with advanced pathological grade. Kaplan–Meier analysis indicated that meningioma patients with low miR-224 expression exhibited significantly prolonged overall and recurrence-free survival. Furthermore, we demonstrated that ERG2 was an identical candidate target gene of MiR-224 in vitro. Our results indicated that downregulation of miR-224 suppressed cell growth and resulted in the enhancement of cell apoptosis through activation of the ERG2-BAK-induced apoptosis pathway. Our findings imply the miR-224 expression could predict the overall survival and recurrence-free survival of patients with meningioma and it might be a promising therapeutic target for treating malignant meningiomas. - Highlights: • MiR-224 expression is correlates with prognosis in meningioma patients. • ERG2 is a novel downstream target of miR-224. • MiR-224 suppressed cell growth and enhanced apoptosis in IOMM-Lee and CH157 cells. • MiR-224 is an upstream regulator of the ERG2

  7. Determining coastal mixing rates of western Taiwan Strait using 224Ra

    International Nuclear Information System (INIS)

    224Ra concentrations in the coastal sea water of western Taiwan Strait in winter were measured using Mn-fiber adsorption-successive emanation scintillation method. 224Ra activities in the seawater of the western Taiwan Strait varied from 0.90 to 16.25 Bq/m3 with an average of 4.60 Bq/m3. The horizontal and vertical distributions of 224Ra were studied. The distributions of 224Ra in the surface water decreased gradually with increasing distance offshore. The apparent horizontal and vertical eddy diffusion coefficients estimated from the one dimensional steady state model of 224Ra were (5.0-55.4) x 106cm2/s and (4.0-51.7) cm2/s, respectively. (author)

  8. MicroRNA-224 targets ERG2 and contributes to malignant progressions of meningioma.

    Science.gov (United States)

    Wang, Maomao; Deng, Xiaodong; Ying, Qi; Jin, Tingyan; Li, Ming; Liang, Chong

    2015-05-01

    MicroRNA-224 is overexpressed in various malignant tumors with poor prognosis, which plays a critical role in biological processes including cell proliferation, apoptosis and several developmental and physiological progressions. However, the potential association between miR-224 and clinical outcome in patients with meningiomas remains unknown. Here, we investigate miR-224 expression and biological functions in meningiomas. MiR-224 expression was measured by Northern blot analysis and quantitative reverse transcription-polymerase chain reaction (qRT-PCR) in meningioma and normal brain tissues. Kaplan-Meier analysis and Cox regression analysis were used to exam its correlation with clinicopathological features and prognostic value. The biological effects of miR-224 on the cell proliferation and apoptosis in meningioma cells were examined by MTT assay and apoptosis assay. We found the expression levels of miR-224 were significantly higher in meningioma tissues than that in normal brain, positively correlated with advanced pathological grade. Kaplan-Meier analysis indicated that meningioma patients with low miR-224 expression exhibited significantly prolonged overall and recurrence-free survival. Furthermore, we demonstrated that ERG2 was an identical candidate target gene of MiR-224 in vitro. Our results indicated that downregulation of miR-224 suppressed cell growth and resulted in the enhancement of cell apoptosis through activation of the ERG2-BAK-induced apoptosis pathway. Our findings imply the miR-224 expression could predict the overall survival and recurrence-free survival of patients with meningioma and it might be a promising therapeutic target for treating malignant meningiomas.

  9. MicroRNA-224 Suppresses Colorectal Cancer Cell Migration by Targeting Cdc42

    Directory of Open Access Journals (Sweden)

    Tao-Wei Ke

    2014-01-01

    Full Text Available The metastatic spread of tumor cells is the major risk factor affecting the clinical prognosis of colorectal cancer (CRC patients. The metastatic phenotype can be modulated by dysregulating the synthesis of different structural and functional proteins of tumor cells. Micro(miRNAs are noncoding RNAs that recognize their cognate messenger (mRNA targets by sequence-specific interactions with the 3′ untranslated region and are involved in the multistep process of CRC development. The objective of this study was to investigate the expression and biological roles of miR-224 in CRC. The miR-224 expression level was assessed by a quantitative real-time PCR in 79 CRC and 18 nontumor tissues. Expression levels of miR-224 in CRC tissues were significantly lower than those in nontumor tissues. Its expression level was associated with the mutation status of the APC gene. Ectopic expression of miR-224 suppressed the migratory ability of CRC cell line, but cell proliferation was less affected. Increased miR-224 diminished Cdc42 and SMAD4 expressions at both the protein and mRNA levels and inhibited the formation of actin filaments. Overall, this study indicated a role of miR-224 in negatively regulating CRC cell migration. The expression level of miR-224 may be a useful predictive biomarker for CRC progression.

  10. Production of actinium, thorium and radium isotopes from natural thorium irradiated with protons up to 141 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Ermolaev, S.V.; Zhuikov, B.L.; Kokhanyuk, V.M.; Matushko, V.L. [Russian Academy of Sciences, Moscow (Russian Federation). Inst. of Nuclear Research; Kalmykov, S.N. [Lomonosov Moscow State Univ., Moscow (Russian Federation). Chemistry Dept.; Aliev, R.A. [Lomonosov Moscow State Univ., Moscow (Russian Federation). Skobeltsyn Inst. of Nuclear Physics; Tananaev, I.G.; Myasoedov, B.F. [Russian Academy of Sciences, Moscow (Russian Federation). A.N. Frumkin Inst. of Physical Chemistry and Electrochemistry

    2012-07-01

    Cross sections of {sup 225}Ac, {sup 227}Ac, {sup 227}Th and {sup 228}Th in thorium-232 targets irradiated with protons in the energy range 21-141 MeV have been measured. Based on these data, production yields of {sup 225}Ac and {sup 223}Ra in thick thorium targets have been calculated. It is possible to produce in proton energy range 60-140 MeV about 96 GBq (2.6 Ci) {sup 225}Ac per 10-d irradiation with 100 {mu}A proton beam current and 10-d decay, and much higher amount of {sup 223}Ra. The impurities of {sup 227}Ac and {sup 224}Ra are important and need to be assessed for further medical applications. (orig.)

  11. Clinical Study of 224 Patients with Hypertriglyceridemia Pancreatitis

    Institute of Scientific and Technical Information of China (English)

    Xiao-Li Zhang; Fei Li; Ya-Min Zhen; Ang Li; Yu Fang

    2015-01-01

    Background:Hypertriglyceridenia (HTG) is the most common etiology of acute pancreatitis (AP) after alcohol and gallstone-induced disease.Elevation of serum triglyceride (TG) levels to ≥ 1000 mg/dl in a patient with AP strongly indicates HTG as the cause.The absolute risk of pancreatitis based on serum TG ≤1000 mg/dl has not been clearly defined.The aims of this study were to address the role of elevated TG levels between 500 and 1000 mg/dl in the clinical course of HTG pancreatitis (HTGP);and assess the relationship between the level of serum TG and disease severity.Methods:A total of 224 HTGP patients between 2007 and 2011 were divided into two subgroups.Totally,122 patients in Group A had serum TG >1000 mg/dl;102 patients in Group B had maximal TG levels between 500 and 1000 mg/dl accompanied by lactescent serum;100 patients with biliary AP and 99 patients with alcoholic AP hospitalized during the study period were enrolled as controls.The clinical and biochemical data were analyzed.Results:The clinical presentation ofHTG-induced pancreatitis was similar to other causes.Severe form of AP in Group A was higher than Group B (x2 =4.002,P =0.045).The severity with HTGP was significantly higher as compared to biliaryAP (x2 =33.533,P =0.000) and alcoholic AP (x2 =7.179,P =0.007).Systemic complications with HTGP were significantly higher than biliary AP (x2 =58.763,P =0.000).Conclusions:The study demonstrated that TG level ≥500 mg/dl should raise a high degree of suspicion,especially if no other etiology of AP is apparent.The severity of HTGP seems to correlate directly with TG level.HTGP seems be more severe than other causes of AP.

  12. 22 CFR 224.16 - Disqualification of reviewing official or ALJ.

    Science.gov (United States)

    2010-04-01

    ... PROGRAM FRAUD CIVIL REMEDIES ACT § 224.16 Disqualification of reviewing official or ALJ. (a) A reviewing... ALJ shall dismiss the complaint without prejudice. (2) If the ALJ disqualifies himself or herself,...

  13. 22 CFR 224.22 - Exchange of witness lists, statements, and exhibits.

    Science.gov (United States)

    2010-04-01

    ... THE PROGRAM FRAUD CIVIL REMEDIES ACT § 224.22 Exchange of witness lists, statements, and exhibits. (a... there is no prejudice to the objecting party. (c) Unless another party objects within the time set...

  14. Autophagy-preferential degradation of MIR224 participates in hepatocellular carcinoma tumorigenesis.

    Science.gov (United States)

    Lan, Sheng-Hui; Wu, Shan-Ying; Zuchini, Roberto; Lin, Xi-Zhang; Su, Ih-Jen; Tsai, Ting-Fen; Lin, Yen-Ju; Wu, Cheng-Tao; Liu, Hsiao-Sheng

    2014-09-01

    Autophagy and microRNA (miRNA) are important regulators during cancer cell tumorigenesis. Impaired autophagy and high expression of the oncogenic microRNA MIR224 are prevalent in hepatocellular carcinoma (HCC); however, the relationship between the 2 phenomena remains elusive. In this study, we are the first to reveal that autophagy selectively regulates MIR224 expression through an autophagosome-mediated degradation system. Based on this finding, we further demonstrated that in hepatitis B virus (HBV)-related HCC, aberrant autophagy (low autophagic activity) results in accumulation of MIR224 and decreased expression of the target gene Smad4, which leads to increased cell migration and tumor formation. Preferential recruitment of MIR224 into the autophagosome was clearly demonstrated by a) miRNA in situ hybridization under confocal microscopy, and b) immunogold labeling of MIR224 under electron microscopy compared with a ubiquitously expressed microRNA MIRlet7e/let-7. Furthermore, we found that off-label use of amiodarone, an antiarrhythmic agent, effectively suppressed HCC tumorigenesis through autophagy-mediated MIR224 degradation both in vitro and in vivo. In summary, we identified amiodarone as a new autophagy inducer, which may provide an alternative approach in HCC therapy through a novel tumor suppression mechanism.

  15. EFFECT OF FK224 ON THE BRONCHOCONSTRICTION INDUCED BY ISOCAPNIC HYPERPNEA IN GUINEA PIGS

    Institute of Scientific and Technical Information of China (English)

    陶梦非; 梁永杰

    2005-01-01

    Objective To evaluate effect of Neurokinin receptor antagonist on the prevention from hyperpnea-induced bronchoconstriction using a dual Neurokinin receptor antagonist FK224. Methods 12 pathogenfree Hartley guinea pigs were divided into two groups randomly: Dimethyl sulfoxide (DMSO) control group (n =6)and FK224 group (n =6). Guinea pigs were anesthetized with pentobarbital sodium. A cervical tracheostomy was performed and a polyethylene tube was inserted into the trachea. After measuring baseline value of the lung resistance (RL) and dynamic compliance of respiratory system (Cdyn) , DMSO (0. 3ml/kg) and FK224 ( 1mg/kg) were administered by injection through jugular vein respectively. A rodent respirator with dry 5% CO2-95% O2 mixture at room temperature provided mechanical ventilation ( VT 8ml/animal, 100breaths/min ) for 5min. RL and Cdyn of 2groups were measured after isocapnic hyperpnea challenge. Results In DMSO control group, isocapnic hyperpnea of dry gas elicited a marked increase in RL and decrease in Cdyn. RL and Cdyn of FK224 group did not change significantly. Conclusion FK224 can inhibit the increase in RL and decrease in Cdyn caused by isocapnic hyperpnea in guinea pigs. And antagonists of tachykinins receptors might have effect on prophylaxis and treatment in exercise-induced asthma.

  16. Long-term clinical investigation of patients with ankylosing spondylitis treated with /sup 224/Ra

    Energy Technology Data Exchange (ETDEWEB)

    Schmitt, E. (Universitatsklinik Friedrichsheim, Frankfurt, West Germany); Ruckbeil, C.; Wick, R.R.

    1983-01-01

    Between 1952 and 1980 about 250 patients with ankylosing spondylitis were treated with /sup 224/Ra at the Orthopaedic University Hospital of Frankfurt/M. In 1970, 119 of them were examined and X-rayed as was another group of 40 patients in 1980. The results of those examined could be compared with a group of 40 patients treated without /sup 224/Ra. Patients with /sup 224/Ra demonstrated a long-lasting period of subjective improvement after the treatment, with reduced consumption of antirheumatoid and analgesic drugs, on the average. Blood examinations show inflammatory activities. Nevertheless, the ankylosing spondylitis proceeded. In the final stages of the disease, neither the clinical aspects nor the X-rays showed any specific changes. We observed no case of malignant bone tumor. Of the 169 examined patients, 22 had a total of 32 children after the treatment with /sup 224/Ra. Among these was a set of twins with cerebral palsy and diabetes insipidus renalis. In conclusion, /sup 224/Ra in ankylosing spondylitis is a recommended treatment without higher risk compared to the common therapy with drugs.

  17. Late effects of radium-224 injected in children and adults survey and comment of a paediatrician

    Energy Technology Data Exchange (ETDEWEB)

    Spiess, H. [Poliklinik Muenchen (Germany)

    2005-07-01

    Radium-224 (Ra-224) was already used as medicament before world war I; but because of serious side effects soon abandoned. It was revived as a remedy for tuberculosis and ankylosing spondylitis after world war II by a country doctor called Troch, supported by the Insurance Company ''Braunschweiger Landesversicherungsanstalt'' and over enthusiastic press reports. The 'new' medicine called 'Peteosthor' was a mixture of Ra-224 with traces of the red dye cosine and platinsol. The propaganda in favour of this therapy was so strong, that the government of Lower Saxony asked the University of Goettingen and others to examine this new 'wonderdrug'. Dr. Troch demanded that it should be used only under his personal supervision. As youngest assistent at the university childrens hospital of the University Goettingen I was sent in 1948 to this hospital in Hildesheim to examine 'Peteosthor'. (orig.)

  18. 25 CFR 224.183 - What other administrative appeals processes also apply?

    Science.gov (United States)

    2010-04-01

    ... DETERMINATION ACT General Appeal Procedures § 224.183 What other administrative appeals processes also apply? The administrative appeal processes in 25 CFR part 2 and 43 CFR part 4, subject to the limitations in... 25 Indians 1 2010-04-01 2010-04-01 false What other administrative appeals processes also...

  19. 77 FR 37732 - Fourteenth Meeting: RTCA Special Committee 224, Audio Systems and Equipment

    Science.gov (United States)

    2012-06-22

    ... Equipment AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION: Meeting Notice of RTCA Special Committee 224, Audio Systems and Equipment. SUMMARY: The FAA is issuing... and Equipment. DATES: The meeting will be held July 11, 2012, from 10 a.m.-4 p.m. ADDRESSES:...

  20. Ra-224 and Ra-226: A New Method for Measuring Groundwater Seepage in Lake Michigan

    Science.gov (United States)

    Stevens, K. R.; Buyan, A. C.; Waples, J. T.

    2008-12-01

    Radium isotopes have been used to estimate groundwater discharge (GWD) in coastal marine waters for decades, but this technique has never before been used in the Laurentian Great Lakes. In this study, we used a RAD7 radon-in-air monitor to measure naturally-occurring radium isotopes Ra-224 (half-life= 3.64 d) and Ra-226 (half-life = 1600 a) in groundwater and three shallow water sites along Lake Michigan's Wisconsin coastline. Radium-224 activities in groundwater ranged from 1153 dpm m-3 in a deep aquifer (New Berlin well no.7) to 31 dpm m-3 in a shallow aquifer (Pryor well). Nearshore Lake Michigan measurements of Ra-224 were lowest at Red Arrow Beach (0.2 dpm m-3), higher in the Milwaukee harbor (GLWI slip, 1.1 dpm m-3) and highest at Harrington Beach (4.1 dpm m-3) and correspond well with groundwater seepage estimates made by Cherkauer et al. (1990) using alternate methods (i.e., where higher radium activity is indicative of higher GWD). These Ra-224 measurements are the first ever made in Lake Michigan (and presumably any of the Great Lakes) and we conclude that, by sampling offshore radium activity gradients, this RAD7 technique is a viable method for directly measuring GWD in Lake Michigan and other freshwater systems.

  1. 77 FR 2343 - Eleventh Meeting: RTCA Special Committee 224, Airport Security Access Control Systems

    Science.gov (United States)

    2012-01-17

    ...). ACTION: Notice of RTCA Special Committee 224, Airport Security Access Control Systems. SUMMARY: The FAA..., Airport Security Access Control Systems. DATES: The meeting will be held February 9, 2012, from 10 a.m.-4..., Airport Security Access Control Systems. The agenda will include the following: February 9, 2012...

  2. 47 CFR 68.224 - Notice of non-hearing aid compatibility.

    Science.gov (United States)

    2010-10-01

    ... (CONTINUED) CONNECTION OF TERMINAL EQUIPMENT TO THE TELEPHONE NETWORK Terminal Equipment Approval Procedures § 68.224 Notice of non-hearing aid compatibility. Every non-hearing aid compatible telephone offered... telephone is not hearing aid compatible, as is defined in §§ 68.4(a)(3) and 68.316, or if offered for...

  3. 5 CFR 591.224 - How does OPM adjust price indexes between surveys?

    Science.gov (United States)

    2010-01-01

    ... this, OPM uses the annual or biennial change in the Consumer Price Index (CPI) for the COLA area... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false How does OPM adjust price indexes between...-Of-Living Allowances § 591.224 How does OPM adjust price indexes between surveys? (a) OPM...

  4. 25 CFR 224.102 - Must a tribe establish a comment or hearing process for addressing environmental concerns?

    Science.gov (United States)

    2010-04-01

    ... addressing environmental concerns? 224.102 Section 224.102 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF... or hearing process for addressing environmental concerns? Yes. The Act (25 U.S.C. 3504(e)(2)(C)(iii... establish an environmental review process under a TERA that: (a) Ensures that the public is notified...

  5. 25 CFR 224.86 - Are there limits on the duration of leases, business agreements, and rights-of-way?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Are there limits on the duration of leases, business agreements, and rights-of-way? 224.86 Section 224.86 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY...

  6. 10 CFR 431.224 - Uniform test method for the measurement of energy consumption for traffic signal modules and...

    Science.gov (United States)

    2010-01-01

    ... consumption for traffic signal modules and pedestrian modules. 431.224 Section 431.224 Energy DEPARTMENT OF... measurement of energy consumption for traffic signal modules and pedestrian modules. (a) Scope. This section... traffic signal modules and pedestrian modules. For purposes of 10 CFR part 431 and EPCA, the...

  7. 25 CFR 224.115 - When in the petition process must the Director investigate a tribe's compliance with a TERA?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false When in the petition process must the Director investigate a tribe's compliance with a TERA? 224.115 Section 224.115 Indians BUREAU OF INDIAN AFFAIRS... process must the Director investigate a tribe's compliance with a TERA? The Director must investigate...

  8. Closure Report for Corrective Action Unit 224: Decon Pad and Septic Systems, Nevada Test Site, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Restoration

    2007-10-01

    Corrective Action Unit (CAU) 224 is located in Areas 02, 03, 05, 06, 11, and 23 of the Nevada Test Site, which is situated approximately 65 miles northwest of Las Vegas, Nevada. CAU 224 is listed in the Federal Facility Agreement and Consent Order (FFACO) of 1996 as Decon Pad and Septic Systems and is comprised of the following nine Corrective Action Sites (CASs): CAS 02-04-01, Septic Tank (Buried); CAS 03-05-01, Leachfield; CAS 05-04-01, Septic Tanks (4)/Discharge Area; CAS 06-03-01, Sewage Lagoons (3); CAS 06-05-01, Leachfield; CAS 06-17-04, Decon Pad and Wastewater Catch; CAS 06-23-01, Decon Pad Discharge Piping; CAS 11-04-01, Sewage Lagoon; and CAS 23-05-02, Leachfield. The Nevada Division of Environmental Protection (NDEP)-approved corrective action alternative for CASs 02-04-01, 03-05-01, 06-03-01, 11-04-01, and 23-05-02 is no further action. As a best management practice, the septic tanks and distribution box were removed from CASs 02-04-01 and 11-04-01 and disposed of as hydrocarbon waste. The NDEP-approved correction action alternative for CASs 05-04-01, 06-05-01, 06-17-04, and 06-23-01 is clean closure. Closure activities for these CASs included removing and disposing of radiologically and pesticide-impacted soil and debris. CAU 224 was closed in accordance with the NDEP-approved CAU 224 Corrective Action Plan (CAP). The closure activities specified in the CAP were based on the recommendations presented in the CAU 224 Corrective Action Decision Document (U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office, 2005). This Closure Report documents CAU 224 closure activities. During closure activities, approximately 60 cubic yards (yd3) of mixed waste in the form of soil and debris; approximately 70 yd{sup 3} of sanitary waste in the form of soil, liquid from septic tanks, and concrete debris; approximately 10 yd{sup 3} of hazardous waste in the form of pesticide-impacted soil; approximately 0.5 yd{sup 3} of universal waste in

  9. Closure Report for Corrective Action Unit 224: Decon Pad and Septic Systems, Nevada Test Site, Nevada

    International Nuclear Information System (INIS)

    Corrective Action Unit (CAU) 224 is located in Areas 02, 03, 05, 06, 11, and 23 of the Nevada Test Site, which is situated approximately 65 miles northwest of Las Vegas, Nevada. CAU 224 is listed in the Federal Facility Agreement and Consent Order (FFACO) of 1996 as Decon Pad and Septic Systems and is comprised of the following nine Corrective Action Sites (CASs): CAS 02-04-01, Septic Tank (Buried); CAS 03-05-01, Leachfield; CAS 05-04-01, Septic Tanks (4)/Discharge Area; CAS 06-03-01, Sewage Lagoons (3); CAS 06-05-01, Leachfield; CAS 06-17-04, Decon Pad and Wastewater Catch; CAS 06-23-01, Decon Pad Discharge Piping; CAS 11-04-01, Sewage Lagoon; and CAS 23-05-02, Leachfield. The Nevada Division of Environmental Protection (NDEP)-approved corrective action alternative for CASs 02-04-01, 03-05-01, 06-03-01, 11-04-01, and 23-05-02 is no further action. As a best management practice, the septic tanks and distribution box were removed from CASs 02-04-01 and 11-04-01 and disposed of as hydrocarbon waste. The NDEP-approved correction action alternative for CASs 05-04-01, 06-05-01, 06-17-04, and 06-23-01 is clean closure. Closure activities for these CASs included removing and disposing of radiologically and pesticide-impacted soil and debris. CAU 224 was closed in accordance with the NDEP-approved CAU 224 Corrective Action Plan (CAP). The closure activities specified in the CAP were based on the recommendations presented in the CAU 224 Corrective Action Decision Document (U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office, 2005). This Closure Report documents CAU 224 closure activities. During closure activities, approximately 60 cubic yards (yd3) of mixed waste in the form of soil and debris; approximately 70 yd3 of sanitary waste in the form of soil, liquid from septic tanks, and concrete debris; approximately 10 yd3 of hazardous waste in the form of pesticide-impacted soil; approximately 0.5 yd3 of universal waste in the form of

  10. miR-224-3p inhibits autophagy in cervical cancer cells by targeting FIP200

    Science.gov (United States)

    Fang, Wang; Shu, Shan; Yongmei, Li; Endong, Zhu; Lirong, Yin; Bei, Sun

    2016-01-01

    Cervical cancer (CC) is a malignant solid tumor, which is one of the main causes of morbidity and mortality in women. Persistent High-risk human papillomavirus (hrHPV) infection is closely related to cervical cancer and autophagy has been suggested to inhibit viral infections. miRNAs have been reported to regulate autophagy in many solid tumors with many studies implicating miR-224-3p in the regulation of autophagy. In this study, we performed a miRNA microarray analysis on CC tissues and found that a large number of miRNAs with differential expressions in hrHPV-infected tissues. We identified miR-224-3p as a candidate miRNA selectively up regulated in HPV-infected tissues and cell lines. Further analysis revealed that miR-224-3p regulates autophagy in cervical cancer tissues and cell lines. While the overexpression of miR-224-3p inhibits autophagy in HPV-infected cells, knocking down endogenous miR-224-3p increases autophagy activity in the same cells. In addition, we found that miR-224-3p directly inhibits the expression of autophagy related gene, FAK family-interacting protein of 200 kDa (FIP200). In summary, we found that miR-224-3p regulates autophagy in hrHPV-induced cervical cancer cells through targeting FIP200 expression. PMID:27615604

  11. miR-224-3p inhibits autophagy in cervical cancer cells by targeting FIP200.

    Science.gov (United States)

    Fang, Wang; Shu, Shan; Yongmei, Li; Endong, Zhu; Lirong, Yin; Bei, Sun

    2016-01-01

    Cervical cancer (CC) is a malignant solid tumor, which is one of the main causes of morbidity and mortality in women. Persistent High-risk human papillomavirus (hrHPV) infection is closely related to cervical cancer and autophagy has been suggested to inhibit viral infections. miRNAs have been reported to regulate autophagy in many solid tumors with many studies implicating miR-224-3p in the regulation of autophagy. In this study, we performed a miRNA microarray analysis on CC tissues and found that a large number of miRNAs with differential expressions in hrHPV-infected tissues. We identified miR-224-3p as a candidate miRNA selectively up regulated in HPV-infected tissues and cell lines. Further analysis revealed that miR-224-3p regulates autophagy in cervical cancer tissues and cell lines. While the overexpression of miR-224-3p inhibits autophagy in HPV-infected cells, knocking down endogenous miR-224-3p increases autophagy activity in the same cells. In addition, we found that miR-224-3p directly inhibits the expression of autophagy related gene, FAK family-interacting protein of 200 kDa (FIP200). In summary, we found that miR-224-3p regulates autophagy in hrHPV-induced cervical cancer cells through targeting FIP200 expression. PMID:27615604

  12. WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene.

    Science.gov (United States)

    Montano, Giorgia; Vidovic, Karina; Palladino, Chiara; Cesaro, Elena; Sodaro, Gaetano; Quintarelli, Concetta; De Angelis, Biagio; Errichiello, Santa; Pane, Fabrizio; Izzo, Paola; Grosso, Michela; Gullberg, Urban; Costanzo, Paola

    2015-09-29

    The Kruppel-like protein ZNF224 is a co-factor of the Wilms' tumor 1 protein, WT1. We have previously shown that ZNF224 exerts a specific proapoptotic role in chronic myelogenous leukemia (CML) K562 cells and contributes to cytosine arabinoside-induced apoptosis, by modulating WT1-dependent transcription of apoptotic genes. Here we demonstrate that ZNF224 gene expression is down-regulated both in BCR-ABL positive cell lines and in primary CML samples and is restored after imatinib and second generation tyrosine kinase inhibitors treatment. We also show that WT1, whose expression is positively regulated by BCR-ABL, represses transcription of the ZNF224 gene. Finally, we report that ZNF224 is significantly down-regulated in patients with BCR-ABL positive chronic phase-CML showing poor response or resistance to imatinib treatment as compared to high-responder patients. Taken as a whole, our data disclose a novel pathway activated by BCR-ABL that leads to inhibition of apoptosis through the ZNF224 repression. ZNF224 could thus represent a novel promising therapeutic target in CML. PMID:26320177

  13. Investigation of 224Ra in the 226Ra (α,α'2n) reaction

    International Nuclear Information System (INIS)

    Positive and negative parity bands have been followed up to 10+ (possibly 12+) and 11- in 224Ra and are compared to the corresponding bands in the isotone 226Th. If a constant value of the intrinsic quadrupole moment is assumed for all E2 transitions in 224Ra the E1/E2 branching ratios are consistent with an intrinsic dipole moment of vertical strokeQ1vertical stroke=0.032(3) e.fm. This small value, as compared to vertical strokeQ1vertical stroke=0.30(2) e.fm for 226Th, can be explained by an almost complete cancellation of large positive liquid-drop and negative shell-model contributions. (orig.)

  14. Biological effects of 224Ra. Benefit and risk of therapeutic application

    International Nuclear Information System (INIS)

    The Second Symposium on the Biological effects of 224Ra, held at Neuherberg, was focused on two topical aspects of radiation protection. One aspect was the long-term effects of high-LET ionizing radiations on man and the quantitative data involved in risk assessment at low doses. The evaluation of epidemiological studies and experimental research was discussed in order to provide facts and figures contributing to an objective assessment of the radiation hazard from incorporated radionuclides. The other aspect was that of radiation protection in medicine. In the case of 224Ra treatment of ankylosing spondylitis the questions of benefit and risk of this therapeutic use of ionizing radiations were discussed, the aim being to achieve the therapeutic effect while reducing radiation exposure - and therefore the hazard - to a minimum. The proceedings contain the complete texts of 23 papers as well as the final round table discussions

  15. Alkali activated materials state-of-the-art report, RILEM TC 224-AAM

    CERN Document Server

    Deventer, Jannie

    2014-01-01

    This is a State of the Art Report resulting from the work of RILEM Technical Committee 224-AAM in the period 2007-2013. The Report summarises research to date in the area of alkali-activated binders and concretes, with a particular focus on the following areas: binder design and characterisation, durability testing, commercialisation, standardisation, and providing a historical context for this rapidly-growing research field.

  16. Fine structures in 14C emission of 223Ra and 224Ra

    International Nuclear Information System (INIS)

    The measurement of the energy spectrum of 14C nuclei emitted in the spontaneous radioactivity from 223Ra and 224Ra has been carried out, using thin and intense sources (480 MBq for 223Ra and 3550 MBq for 224Ra). The sources were obtained by implanting mass-separated beams from ISOLDE (CERN) into Al and vitreous C catchers. The measurement was performed with the supraconducting solenoidal spectrometer SOLENO installed at Orsay. The discovery, of a fine structure in the energy spectrum of 14C emission from 223Ra, which is analogous to the one known for α emission, is confirmed. Only 13% of the branching ratio in 14C decay leads to the ground state of the residual nucleus, while 8l% to the first excited state. For 14C emission of 224Ra, a lower limit of 2 for the hindrance factor has been measured for the transition to the first excited state in the residual nucleus. Also, a precise identification in Z with a E·ΔE telescope has been performed for the radiation from the 223Ra source. (author) 22 refs., 11 figs., 1 tab

  17. Fine structure in 14C emission from 223Ra and 224Ra

    International Nuclear Information System (INIS)

    The measurement of the energy spectrum of 14C nuclei emitted in the spontaneous radioactivity of 223Ra and 224Ra has been carried out, using thin and intense sources (480 MBq for 223Ra and 3550 MBq for 224Ra). The sources were obtained by implanting mass-separated beams into Al and vitreous C catchers. The measurement was performed with a superconducting solenoidal spectrometer. Our discovery, previously reported, of fine structure in the energy spectrum of 14C emission from 223Ra, which is analogous to the one known for α emission, is confirmed. Only 13% of the branching ratio in 14C decay leads to the ground state of the residual nucleus, while 81% to the first excited state. For 14C emission from 224Ra, a lower limit of 2 for the hindrance factor has been measured for the transition to the first excited state in the residual nucleus. Also, a precise identification in Z with an ExΔE telescope has been performed for the radiation from the 223Ra source. Our measurements of fine structure in 14C emissions open this field to nuclear structure studies

  18. C.I.颜料红224颜料化工艺改进%Improvement on Pigmentation of C.I. Pigment Red 224

    Institute of Scientific and Technical Information of China (English)

    梁铁夫; 闫燕

    2012-01-01

    本文着重对C.I.颜料红224的颜料化工艺进行了改进.选用80%醋酸为颜料化介质,液固比15∶1,颜料化温度104~ 106℃的颜料化工艺,过滤得到的滤饼直接真空烘干.与传统的浓硫酸酸胀的工艺相比,解决了废酸水的污染问题,收率大幅提高,产品质量达到国外标准品质量.

  19. Analysis on incidence reason of 224 pulmonary tuberculosis patients%224例肺结核病人发病原因分析

    Institute of Scientific and Technical Information of China (English)

    江秉态

    2013-01-01

    目的:探讨现阶段引起结核病发病的主要原因,为预防和控制结核病提供理论依据。方法:通过对旌阳区结核病防治所在2010年6月至2011年6月期间登记的224例新发涂阳肺结核病人进行回顾性问卷调查,对可能引起发病的原因进行分析。结果:224例肺结核病人中,有麻将史103例(46.0%),有网吧上网史38例(17.0%),有外出打工史20例(8.9%),有家人或同事患结核病14例(6.3%),同时有麻将史和打工史13例(5.8%),同时有麻将史和家庭接触史8例(3.6%),从事美容美发6例(2.6%),有在游戏厅玩游戏史的2例(0.9%),从事废品收购2例(0.9%),从事扫地工作1例(0.4%),其他17例(7.6%)。结论:在麻将馆打麻将和在网吧上网是目前引起结核病发病的主要原因,加强对麻将场馆和网吧等公共场所的监督与管理,并采取积极的干预措施势在必行。%Objective:To explore the main reason caused by tuberculosis at the present stage,to provide a theoretical basis for the prevention and control of tuberculosis. Methods:224 new smear-positive pulmonary tuberculosis patients who were registered during June 2010 to June 2011 in Jingyang District Tuberculosis Control Center were analyzed by retrospective questionnaires,to find the main reason of tuberculosis. Results:Among the 224 cases,103 cases with mahjong history(46.0%) ,38 cases with internet history (17.0%),20 cases with history of migrant workers(8.9%), 14 cases with family or colleagues suffering from tuberculosis(6.3%),13 cases with history of mahjong and migrant workers(5.8%),8 cases with history of mahjong and family or colleagues suffering from tuberculosis(3.6%), 8 cases with engaging in Beauty salon(2.6%),2 cases with history of playing games in the games room(0.9%),2 cases with engaging in the acquisition of waste(0.9%),1 case with engaging in sweeping work(0.4%), the other 17 cases(7

  20. 亿维发布UN CPU224 DC/DC/DC

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    2011年12月.亿维(UniMAT)正式发布了UN CPU224DC/DC/DC.订货号为UN214-1AD23—0XB0。这是一款由亿维研发部根据多年PLC模块的市场经验.历时1年研发出来的200系列自主品牌PLC控制器模块.在兼容西门子PLC功能的前提下,做了部分优化及功能增强。

  1. Determination of 226Ra and 224Ra in drinking waters by liquid scintillation counting

    International Nuclear Information System (INIS)

    A method for the determination of Ra-isotopes in water samples has been developed. Ra is coprecipitated with Ba as sulphate. The precipitate is then dissolved with EDTA and counted with a liquid scintillation system after mixing with a scintillation cocktail. The study of the temporal evolution of the separated activity gives the isotopic composition of the sample, i.e. the 224Ra and 226Ra contribution to the total activity. The method has been applied to some Spanish drinking waters. (author)

  2. Hyperon production inbar pp interactions at 22.4 GeV/ c

    Science.gov (United States)

    Herynek, I.; Muríň, P.; Staroba, P.; Suk, M.; Šimák, V.; Valkárová, A.; Vávra, J.

    1993-07-01

    In the present paper we investigate the production of charged hyperons and antihy-perons inbar pp interactions at 22.4 GeV/ c recorded in the 2m hydrogen bubble chamber “Ludmila”. After correction for losses due to the kinematics of hyperon decays and for scanning efficiency we have obtained 610 events with charged hyperons or antihyperons. A total cross section of 1.3{-0.05/+0.4} mb for ∑±/overline {sum ^ ± } has been obtained, and various associated charged particle multiplicity distributions are presented.

  3. Agent Based Manufacturing Capability Assessment in the Extended Enterprise Using Step AP224 and XML

    Science.gov (United States)

    Ratchev, Svetan; Medani, Omar

    Data exchange in the extended enterprise is one of the most critical tasks in supporting collaborative decision-making. Companies often rely on geographically distributed suppliers for efficient product design and manufacture. Early design assessment can substantially reduce the cost of product development and production. This research proposes a new STEP AP224 EXPRESS based data model to facilitate the exchange of part and process data between distributed key agents in the early design process. The approach is illustrated using a prototype XML/CORBA environment to support the information exchange between collaborating design and manufacturing agents.

  4. 224例住院婴幼儿贫血病因分析%Analysis of the Cause of Anemia in 224 Cases of Infants and Young Children

    Institute of Scientific and Technical Information of China (English)

    杨俊杰

    2015-01-01

    Objective To study the hospitalized infants and young children crowd in children with anemia, provide theoretical basis for the prevention and treatment of anemia in infants. Methods On 2010.8.1~2010.8.30 hospitalized in our department infant anemia investigation, to find the cause and fol ow-up. Results A total of 224 cases of infants and young children to complete fol ow-up. The most common etiology anemia is iron deficiency disease (69.4%), but 89.3% of them are mild, hemolytic anemia take second place, with favism is given priority to, and send out the Mediter anean anemia; Because of the repeated infection or third of anemia with other diseases. Conclusion Iron deficiency anemia is stil the infant anemia main reason, it is necessary to further strengthen the anemia prevention and control work.%目的探讨住院患儿中婴幼儿人群贫血原因,为防治婴幼儿贫血提供理论依据。方法对2010年8月1日~2013年8月30日在我科住院婴幼儿进行贫血调查,查找病因并进行随访。结果共224例婴幼儿完成随访。贫血病因以缺铁性病最常见(69.4%),但其中89.3%均为轻度表现,溶血性贫血次之,以蚕豆病为主,并有散发地中海贫血;因反复感染或伴随其它疾病的贫血占第3位。结论缺铁性贫血仍是婴幼儿贫血主要原因,有必要进一步加强对贫血防治工作。

  5. 224例住院婴幼儿贫血病因分析%Analysis of the Cause of Anemia in 224 Cases of Infants and Young Children

    Institute of Scientific and Technical Information of China (English)

    杨俊杰

    2015-01-01

    目的探讨住院患儿中婴幼儿人群贫血原因,为防治婴幼儿贫血提供理论依据。方法对2010年8月1日~2013年8月30日在我科住院婴幼儿进行贫血调查,查找病因并进行随访。结果共224例婴幼儿完成随访。贫血病因以缺铁性病最常见(69.4%),但其中89.3%均为轻度表现,溶血性贫血次之,以蚕豆病为主,并有散发地中海贫血;因反复感染或伴随其它疾病的贫血占第3位。结论缺铁性贫血仍是婴幼儿贫血主要原因,有必要进一步加强对贫血防治工作。%Objective To study the hospitalized infants and young children crowd in children with anemia, provide theoretical basis for the prevention and treatment of anemia in infants. Methods On 2010.8.1~2010.8.30 hospitalized in our department infant anemia investigation, to find the cause and fol ow-up. Results A total of 224 cases of infants and young children to complete fol ow-up. The most common etiology anemia is iron deficiency disease (69.4%), but 89.3% of them are mild, hemolytic anemia take second place, with favism is given priority to, and send out the Mediter anean anemia; Because of the repeated infection or third of anemia with other diseases. Conclusion Iron deficiency anemia is stil the infant anemia main reason, it is necessary to further strengthen the anemia prevention and control work.

  6. Bit Optimizing Experimental Study on Q2-24 Well%Q2-24井钻头优选试验研究

    Institute of Scientific and Technical Information of China (English)

    陈波; 于文华; 文平; 陈志学

    2004-01-01

    玉门油田青西地区地层可钻性变化较大,钻头选型困难,导致机械钻速较低.在Q2-24井钻井过程中试验应用了BEST公司的PDC钻头和HUGHES公司的三牙轮钻头,结果表明:该地区弓形山组地层开始直到中沟组泥岩段(2200~3500m)夹杂砂岩、砾岩的地层,使用小尺寸、大倒角的PDC钻头是适宜的,但需认真分析岩性及井下情况,并参阅邻井PDC钻头使用资料,确定合理的钻井参数和钻具组合,以提高机械钻速,缩短钻井周期;与国产钻头相比,HUGHES钻头的的机械钻速较高,钻头的轴承和胎体材质较好,与国产钻头相比,能承受更大钻压.

  7. Microscopic study of positive-parity yrast bands of 224−234Th isotopes

    Indian Academy of Sciences (India)

    Daya Ram; Rani Devi; S K Khosa

    2013-06-01

    The positive-parity bands in 224−234Th are studied using the projected shell model (PSM) approach. The energy levels, deformation systematics, (2) transition probabilities and nuclear -factors are calculated and compared with the experimental data. The calculation reproduces the observed positive-parity yrast bands and (2) transition probabilities. Measurement of (2) transition probabilities for higher spins and -factors would be a stringent test for our predictions. The results of theoretical calculations indicate that the deformation systematics in 224−234Th isotopes depend on the occupation of low components of high j orbits in the valence space and the deformation producing tendency of the neutron–proton interaction operating between spin orbit partner (SOP) orbits, the $[(2g_{9/2}_{}) - (2g_{7/2})_{}]$ and $[(1i_{13/2})_{} - (1i_{11/2})_{}]$ SOP orbits in the present context. In addition, the deformation systematics also depend on the polarization of $(1h_{11/2})_{}$ orbit. The low-lying states of yrast spectra are found to arise from 0-quasiparticle (qp) intrinsic states whereas the high-spin states turn out to possess composite structure.

  8. The segregation of starless and protostellar clumps in the Hi-GAL l=224deg region

    CERN Document Server

    Olmi, L; Elia, D; Jones, P

    2016-01-01

    Stars form in dense, dusty structures, which are embedded in larger clumps of molecular clouds often showing a clear filamentary structure on large scales (> 1pc). One of the best-studied regions in the Hi-GAL survey can be observed toward the l=224deg field. Here, a filamentary region has been studied and it has been found that protostellar clumps are mostly located along the main filament, whereas starless clumps are detected off this filament and are instead found on secondary, less prominent filaments. We want to investigate this segregation effect and how it may affect the clumps properties. We mapped the 12CO(1-0) line and its main three isotopologues toward the two most prominent filaments observed toward the l=224deg field using the Mopra radio telescope, in order to set observational constraints on the dynamics of these structures and the associated starless and protostellar clumps. Compared to the starless clumps, the protostellar clumps are more luminous, more turbulent and lie in regions where the...

  9. Long term investigation of late effects in ankylosing spondylitis patients treated with radium-224

    Energy Technology Data Exchange (ETDEWEB)

    Wick, R.R. [GSF - National Research Center for Environment and Health, Inst. of Radiobiology, Neuherberg (Germany); Nekolla, E.A. [Federal Office for Radiation Protection (BfS), Neuherberg (Germany)

    2005-07-01

    An epidemiological study has been carried out on 1462 ankylosing spondylitis (AS) patients followed since 1971 at the GSF - National Research Center for Environment and Health. The aim of the study was to ascertain the late health effects occurring in these patients who had received repeated intravenous injections of the short lived {alpha}-emitter {sup 224}radium between 1948 and 1975 (excluding patients treated additionally with X-rays). The then usual therapeutic protocol consisted of a total of 10 to 12 injections of 1.036 MBq (28 {mu}Ci) of {sup 224}Ra each, given at weekly intervals. This resulted in a cumulative {alpha}-dose of 0.56 to 0.67 Gy to the marrow-free skeleton (bone surface dose: {proportional_to} 5.5 Gy) of a 70-kg-man (standard man). These patients have been followed together with a control group of 1324 ankylosing spondylitis patients not treated with radioactive drugs and/or X-rays. Up to August 2004, causes of death have been ascertained for 913 exposed patients and 971 controls (mean follow-up time {proportional_to} 26 yr in the exposed group or {proportional_to} 24 yr in the control group). In the exposed group there has been a total of 251 malignant diseases (vs. 277.0 expected cases) and 233 cases (vs. 302.4 exp.) among the controls. In the exposure group 16 cases of kidney cancer (vs. 8.7 cases expected, p = 0.02), 6 cases of liver cancer (vs. 3.3 exp., p = 0.12), and 4 cases of thyroid cancer (vs. 1.1 exp., p = 0.03) were observed. The most striking observation, however, were the 16 cases of leukaemia in the exposure group (vs. 6.5 cases expected, p = 0.001) compared to only 10 cases of leukaemia in the control group (vs. 7.1 cases expected, p = 0.2). Further subclassification of the leukaemias demonstrated a high increase of myeloid leukaemia in the exposure group (10 cases obs. vs. 2.8 cases exp., p <0.001), and particularly, of myeloid leukaemia (7 cases observed vs. 1.7 expected, p = 0.002), whereas in the control group the number

  10. Error-control and processes optimization of (223/224)Ra measurement using Delayed Coincidence Counter (RaDeCC).

    Science.gov (United States)

    Xiaoqing, Cheng; Lixin, Yi; Lingling, Liu; Guoqiang, Tang; Zhidong, Wang

    2015-11-01

    RaDeCC has proved to be a precise and standard way to measure (224)Ra and (223)Ra in water samples and successfully made radium a tracer of several environmental processes. In this paper, the relative errors of (224)Ra and (223)Ra measurement in water samples via a Radium Delayed Coincidence Count system are analyzed through performing coincidence correction calculations and error propagation. The calculated relative errors range of 2.6% ∼ 10.6% for (224)Ra and 9.6% ∼ 14.2% for (223)Ra. For different radium activities, effects of decay days and counting time on final radium relative errors are evaluated and the results show that these relative errors can decrease by adjusting the two measurement factors. Finally, to minimize propagated errors in Radium activity, a set of optimized RaDeCC measurement parameters are proposed. PMID:26233651

  11. Synthesis, characterisation, stereochemistry and antimicrobial activity of 5 -piperazino- and 5-morpholinoacetyl-2,2,4-trimethyl-1, 5-benzodiazepines

    Indian Academy of Sciences (India)

    S Ponnuswamy; A Akila; D Deepa Rajakumari; V Shreevidhyaa Suressh; G Usha

    2015-11-01

    Three 1,5-benzodiazepines viz., 5-chloroacetyl-, 5-piperazinoacetyl- and N5 -morpholinoacetyl-2,2,4-trimethyl-1H-1,5-benzodiazepines have been synthesized. The structural characterisation and the conformational preferences of the compounds have been carried out using IR, 1D and 2D NMR spectral data. The NMR spectral data show that the -acetyltetrahydro-1,5-benzodiazepines prefer to exist in boat conformation with exo orientation of >C=O at 5 position in the solution state. The X-ray crystal structure of 5-morpholinoacetyl-2,2,4-trimethyl-1H-1,5-benzodiazepine also supports boat conformation in the solid state. The antimicrobial activity for -acetyltetrahydro-1,5-benzodiazepines have been carried out. -morpholinoacetyl-2,2,4-trimethyl-1H-1,5-benzodiazepine demonstrated better antibacterial and antifungal activities.

  12. Effect of shell structure on neutron multiplicity of fissioning systems 220,222,224Th nuclei

    Directory of Open Access Journals (Sweden)

    Goyal Savi

    2015-01-01

    Full Text Available The pre- and post-scission neutron multiplicities have been extracted for the 220,222,224Th nuclei for the excitation energy range of 40 MeV to 64 MeV using the National Array of Neutron Detectors (NAND. The Th isotopes are populated from the fusion reaction of 16O+204,206,208Pb systems in order to investigate the dynamics of fusion-fission reactions using the neutron multiplicity as a probe. The theoretical calculations were performed using the Bohr-Wheeler fission width as well as the dissipative dynamical fission width from Kramers prescription. It is observed that the Bohr-Wheeler fission width underestimates the pre-scission yields to a large extent. A large amount of dissipation is required in the Kramers width to fit the observed pre-scission neutron multiplicities.

  13. Low-Lying Collective Levels in 224-234 Th Nuclei

    Directory of Open Access Journals (Sweden)

    Diab S. M.

    2008-04-01

    Full Text Available The low-lying collective levels in 224-234 Th isotopes are investigated in the frame work of the interacting boson approximation model (IBA-1. The contour plot of the potential energy surfaces, V(beta,gamma, shows two wells on the prolate and oblate sides which indicate that all thorium nuclei are deformed and have rotational characters. The levels energy, electromagnetic transition rates B(E1 and B(E2 are calculated. Bending at angular momentum $I^+ = 20$ has been observed for 230 Th. Staggering effect has been calculated and beat patterns are obtained which indicate the existence of an interaction between the ground state band, (GSB, and the octupole negative parity band, (NPB. All calculated values are compared with the available experimental data and show reasonable agreement.

  14. Epidemiological assessment of lens opacifications that impaired vision in patients injected with radium-224

    International Nuclear Information System (INIS)

    The incidence of lens opacifications that impaired vision (cataract) was analyzed among 831 patients who were injected with known dosages of 224Ra in Germany shortly after World War II. The dependence of the incidence on dosage, i.e., injected activity per unit body weight, and on time after treatment was determined. The observations are equally consistent with proportionality of the incidence of cataract to the square of dosage or with a linear dependence beyond a threshold of 0.5 MBq/kg. The possibility of a linear dependence without threshold was strongly rejected (P less than 0.001). The analysis of temporal dependences yielded a component that was correlated with the injected amount of 224Ra and a component that was uncorrelated. The former was inferred by a maximum likelihood analysis to increase approximately as the square of the time after treatment. The component unrelated to the treatment was found to increase steeply with age and to become dominant within the collective of patients between age 50 and 60. The relative magnitudes of the two components were such that a fraction of 55 to 60% of the total of 58 cataracts had to be ascribed to the dose-related incidence. Impaired vision due to cataract was diagnosed before age 54 in 25 cases. In terms of injected activity per unit body weight no dependence of the sensitivity on age was found; specifically there was no indication of a faster occurrence of the treatment-related cataracts in patients treated at older ages

  15. 浅析西门子CPU224CN与smart700触摸屏的通信设置%Analysis of Siemens CPU224CN and Smart700 Touch Screen-based Communication Settings

    Institute of Scientific and Technical Information of China (English)

    廖世海; 夏路生; 贾彬

    2013-01-01

    In this paper,Siem ens S7-200PLC (C PU 224C N ) and sm art700 com poses three conveyor control system as an exam ple,Siem ens S7-200 (C PU 224C N ) com m unication w ith the Siem ens sm art700 touch screen set-tings,and com m unication m ay encounterproblem sare introduced.Forinitialusing touch screen w orkersitisvery helpful.%  本文以西门子S7-200PLC(C PU 224C N)和sm art700组成的三条传送带控制系统为例,介绍了西门子S7-200(C PU 224C N )与西门子sm art700触摸屏之间的通信设置以及通信时可能会遇到的问题。这对于初次使用这种触摸屏做工程的人来说,帮助非常大。

  16. 25 CFR 224.75 - What must the Secretary do upon approval or disapproval of a final proposed TERA?

    Science.gov (United States)

    2010-04-01

    ... INTERIOR ENERGY AND MINERALS TRIBAL ENERGY RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT Approval of Tribal Energy Resource Agreements § 224.75 What must the... subsequent amendments or supplements to the TERA. (b) To disapprove the final proposed TERA Send the tribe...

  17. Acute inhalation of 2,2,4-trimethylpentane alters visual evoked potentials and signal detection behaviour of rats.

    Science.gov (United States)

    The volatile organic compound 2,2,4-trimethylpentane (TMP, “isooctane”) is a primary constituent of gasoline for which the current health effects data are insufficient to permit EPA to conduct a risk assessment. We evaluated potential neurological impairment from acute inhalati...

  18. Determination of 226Ra, 224Ra, 223Ra and 228Ra in mineral water samples of the Slovak Republic

    International Nuclear Information System (INIS)

    The Slovak Republic is very rich in mineral water sources. In recent years, it has been discovered that a number of mineral waters in the Slovak Republic contain high levels of 226Ra and 228Ra. Moreover, there is a lack of information on 224Ra and 223Ra concentrations in mineral waters as well. The currently approved techniques for alpha emitting radium isotopes are based on radon emanation methods. Due to the long ingrowth periods required by these techniques, any 224Ra and 223Ra in the sample decay away and go undetected. For this reason, we have used an alpha spectrometric method for the simultaneous determination of 226Ra, 223Ra and 224Ra. Radium was concentrated by a lead sulphate co-precipitation. The precipitate was dissolved in EDTA and the radium isotopes were separated from possible interfering radionuclides using barium sulphate micro precipitation. The radium-barium precipitate was filtered and counted by alpha spectrometry. 133Ba was used to quantify the yield by gamma spectrometry. In our laboratory, gamma spectrometry was also used for the determination of 228Ra in mineral water samples. Radium was concentrated by a lead-barium sulphate co-precipitation. 133Ba was used to quantify the yield, found to be 97 % on the average, by gamma spectrometry. Furthermore, the committed effective doses for 226Ra, 224Ra, 223Ra, 228Ra intake via ingestion of mineral waters for the members of public were calculated. (author)

  19. 25 CFR 224.116 - What is the time period in which the Director must investigate a tribe's compliance with a TERA?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is the time period in which the Director must investigate a tribe's compliance with a TERA? 224.116 Section 224.116 Indians BUREAU OF INDIAN AFFAIRS... period in which the Director must investigate a tribe's compliance with a TERA? (a) If the...

  20. The segregation of starless and protostellar clumps in the Hi-GAL ℓ = 224° region

    Science.gov (United States)

    Olmi, L.; Cunningham, M.; Elia, D.; Jones, P.

    2016-10-01

    Context. Stars form in dense, dusty structures, which are embedded in larger clumps of molecular clouds often showing a clear filamentary structure on large scales (≳1 pc). The origin (e.g., turbulence or gravitational instabilities) and evolution of these filaments, as well as their relation to clump and core formation, are not yet fully understood. A large sample of both starless and protostellar clumps can now be found in the Herschel Infrared GALactic Plane Survey (Hi-GAL) key project, which also provides striking images of the filamentary structure of the parent molecular clouds. Recent results indicate that populations of clumps on and off filaments may differ. Aims: One of the best-studied regions in the Hi-GAL survey can be observed toward the ℓ = 224° field. Here, a filamentary region has been studied and it has been found that protostellar clumps are mostly located along the main filament, whereas starless clumps are detected off this filament and are instead found on secondary, less prominent filaments. We want to investigate this segregation effect and how it may affect the clumps properties. Methods: We mapped the 12CO (1-0) line and its main three isotopologues toward the two most prominent filaments observed toward the ℓ = 224° field using the Mopra radio telescope, in order to set observational constraints on the dynamics of these structures and the associated starless and protostellar clumps. Results: Compared to the starless clumps, the protostellar clumps are more luminous, more turbulent and lie in regions where the filamentary ambient gas shows larger linewidths. We see evidence of gas flowing along the main filament, but we do not find any signs of accretion flow from the filament onto the Hi-GAL clumps. We analyze the radial column density profile of the filaments and their gravitational stability. Conclusions: The more massive and highly fragmented main filament appears to be thermally supercritical and gravitationally bound

  1. Determination of 226Ra and 224Ra in sediments samples by liquid scintillation counting

    International Nuclear Information System (INIS)

    An experimental procedure has been developed for a rapid determination of the activity concentration of 226Ra and 224Ra in sediments by liquid scintillation counting. The importance of the method lies in its application to the measurement of sediments where the Ra-isotopes activity concentration has been increased due to an anthropomorphic enhancement based on releases of naturally occurring radioactive material (NORM). A sample pre-treatment, including a digestion with aqua regia and a precipitation of hydroxides, was applied to samples before the radium extraction, which was made by co-precipitation with barium. Measurements were done in a low background scintillation spectrometer Quantulus 1220, which can separate and detect simultaneously α and β particles. Additionally, some improvements are suggested for a better α and β interference correction of the results. The obtaining of radiochemical yields is also improved using 133Ba as tracer, which decays by emission of conversion electrons and γ-rays; the wide range of radiochemical yields obtained confirms the need of this analyses. The procedure has been applied to the measurement of riverbed sediments from an estuary in the south-west of Spain, affected in the past by direct and indirect phosphogypsum discharges

  2. The Properties of H{\\alpha} Emission-Line Galaxies at $z$ = 2.24

    CERN Document Server

    An, F X; Wang, W -H; Huang, J -S; Kong, X; Wang, J -X; Fang, G W; Zhu, F; Gu, Q -S; Wu, H; Hao, L; Xia, X -Y

    2014-01-01

    Using deep narrow-band $H_2S1$ and $K_{s}$-band imaging data obtained with CFHT/WIRCam, we identify a sample of 56 H$\\alpha$ emission-line galaxies (ELGs) at $z=2.24$ with the 5$\\sigma$ depths of $H_2S1=22.8$ and $K_{s}=24.8$ (AB) over 383 arcmin$^{2}$ area in the ECDFS. A detailed analysis is carried out with existing multi-wavelength data in this field. Three of the 56 H$\\alpha$ ELGs are detected in Chandra 4 Ms X-ray observation and two of them are classified as AGNs. The rest-frame UV and optical morphologies revealed by HST/ACS and WFC3 deep images show that nearly half of the H$\\alpha$ ELGs are either merging systems or with a close companion, indicating that the merging/interacting processes play a key role in regulating star formation at cosmic epoch z=2-3; About 14% are too faint to be resolved in the rest-frame UV morphology due to high dust extinction. We estimate dust extinction form SEDs. We find that dust extinction is generally correlated with H$\\alpha$ luminosity and stellar mass (SM). Our res...

  3. Lepton Flavor Violation within a realistic SO(10)/G(224) Framework

    CERN Document Server

    Babu, K S; Rastogi, P K; Pati, Jogesh C.; Rastogi, Parul

    2005-01-01

    Lepton flavor violation (LFV) is studied within a realistic unified framework, based on supersymmetric SO(10) or an effective G(224) = SU(2)_L\\times SU(2)_R\\times SU(4)^c symmetry, that successfully describes (i) fermion masses and mixings, (ii) neutrino oscillations, as well as (iii) CP violation. LFV emerges as an important prediction of this framework, bringing no new parameters, barring the few SUSY parameters, which are assumed to be flavor-universal at M^*>= M_{GUT}. We study LFV (i.e. \\mu -> e\\gamma, \\tau -> \\mu\\gamma, \\tau -> e\\gamma and \\mu N -> e N) within this framework by including contributions both from the presence of the right handed neutrinos as well as those arising from renormalization group running in the post-GUT regime (M^* to M_{GUT}). Typically the latter, though commonly omitted in the literature, is found to dominate. Our predicted rates for \\mu -> e\\gamma show that while some choices of (m_o, m_{1/2}) are clearly excluded by the current empirical limit, this decay should be seen wit...

  4. Do nuclei go pear-shaped? Coulomb excitation of 220Rn and 224Ra at REX-ISOLDE (CERN

    Directory of Open Access Journals (Sweden)

    Scheck M.

    2015-01-01

    Full Text Available The IS475 collaboration conducted Coulomb-excitation experiments with post-accelerated radioactive 220Rn and 224Ra beams at the REX-ISOLDE facility. The beam particles (Ebeam: 2.83 MeV/u were Coulomb excited using 60Ni, 114Cd, and 120Sn scattering targets. De-excitation γ-rays were detected employing the Miniball array and scattered particles were detected in a silicon detector. Exploiting the Coulomb-excitation code GOSIA for each nucleus several matrix elements could be obtained from the measured γ-ray yields. The extracted ‹3−||E3||0+› matrix element allows for the conclusion that, while 220Rn represents an octupole vibrational system, 224Ra has already substantial octupole correlations in its ground state. This finding has implications for the search of CP-violating Schiff moments in the atomic systems of the adjacent odd-mass nuclei.

  5. Investigation of $\\alpha$-decay rates of $^{221}$Fr, $^{224}$Ra and $^{226}$Ra in different environments

    CERN Multimedia

    2007-01-01

    It has recently been suggested, and indicated experimentally, that $\\alpha$- decay half-lives are modified by solid state effects in the surrounding environment. We propose here to measure with high accuracy the $\\alpha$-decay half-life of $^{221}$Fr, $^{224}$Ra and $^{226}$Ra in insulators and metals. Furthermore we plan to investigate the temperature dependency of the half-life in these materials (room temperature, 4 K and 10 mK).

  6. Long-term investigation of the risk of malignant diseases following intravenous radium-224 treatment for ankylosing spondylitis; Langzeituntersuchung zum Risiko maligner Erkrankungen nach intravenoeser Behandlung des Morbus Bechterew mit Radium-224

    Energy Technology Data Exchange (ETDEWEB)

    Schulte, Tobias L. [Klinik und Poliklinik fuer Allgemeine Orthopaedie und Tumororthopaedie, Universitaetsklinikum Muenster (Germany); Nekolla, Elke A. [Bundesamt fuer Strahlenschutz (BfS), Neuherberg (Germany); Wick, Roland R. [Inst. fuer Strahlenbiologie, Helmholtz-Zentrum Muenchen, Deutsches Forschungszentrum fuer Gesundheit und Umwelt, Neuherberg (Germany)

    2009-09-15

    Background and purpose: in German-speaking countries, the intravenous treatment of ankylosing spondylitis (AS) with radium-224 ({sup 224}Ra) was common between the late 1940s and 2005. In this long-term investigation, the risk of malignant diseases following intravenous {sup 224}Ra treatment for AS was assessed. Patients and methods: in a prospective long-term study, 1,471 patients with AS who were treated with {sup 224}Ra between 1948 and 1975 have been followed together with a control group of 1,324 AS patients treated neither with radioactive drugs nor with X-rays. Standardized questionnaires to evaluate the patients' health status were used. Observed numbers of malignant diseases were compared with those of the control group as well as with expected numbers for a normal population. Results: After 26 years of follow-up, causes of death have been certified for 1,006 patients of the exposure group (control group: 1,072 patients). Significantly increased rates of myeloid leukemia (12 cases observed vs. 2.9 expected; p < 0.001), kidney cancer (18 vs. 9.1; p < 0.01), thyroid cancer (4 vs. 1.2; p = 0.03) and borderline significantly increased rates of cancer of female genital organs (10 vs. 5.6; p = 0.06) were found in the exposure group in contrast to no significant increases of these diseases in the control group. Rates of pulmonary and gastrointestinal malignancies were not increased. Lymphatic leukemia (exposure group: 8 vs. 2.7; p < 0.01; control group: 7 vs. 3; p = 0.03) was significantly elevated due to a high rate of chronic lymphatic leukemia in both, the exposure as well as the control group. Conclusion: treatment of AS with {sup 224}Ra led to increased incidences of myeloid leukemia and malignancies of kidneys, thyroid and female genital organs. Although this kind of therapy is now abandoned, there is a need for close follow-up of patients who received it. (orig.)

  7. Measurement of 223Ra and 224Ra via RaDeCC and its application at Liaohe River Estuary%辽河口水体中223Ra、224Ra的RaDeCC法测定及应用

    Institute of Scientific and Technical Information of China (English)

    许博超; 姚庆祯; 江雪艳; 于志刚

    2012-01-01

    介绍了同步延时计数法,并应用其对辽河口水体中的223 Ra和224 Ra进行了测定,结合pH、DO、COD、叶绿素、营养盐等参数对223 Ra和224 Ra的放射性活度及其比值随盐度的变化和影响因素进行了讨论,继而以“镭同位素表观年龄模型”计算了辽河口水体的停留时间.结果表明:2010年4月,辽河口调查水域水体中的224 Ra、223 Ra随盐度变化趋势不保守,在盐度为10和26的海域出现了放射性活度高峰值,可能分别由悬浮颗粒物解吸和滨岸咸化的地下水排放等因素造成.水体停留时间随着离开河口距离的增大而增大,最大值出现在盐度为14的海域,达到8.34 d.%Radium delayed coincidence countering system has become the state-of-the-art technique for short-lived radium isotopes (223Ra, 224Ra) measurement. In this paper, we described this system, and used it to measure 223Ra, 224Ra activities at the Liaohe River Estuary. Other parameters, like pH, DO, COD, petroleum hydrocarbon, chlorophyll and nutrients, were used to demonstrate the distribution and impact factors of isotopes activity and ratio versus salinity. Furthermore, the "Apparent Radium Age" model was applied to assess the water residence time at this area. Ra and Ra were not conservative with salinity at the studying area in A-pril, 2010. Two peak activities at salinity 10 and 26 were caused by suspended particles desorption and submarine groundwater discharge , respectively. Water residence time increased with the distance. The oldest age was 8. 34 days at the area with salinity of 14.

  8. Study on the risk of late damage in humans after incorporation of the short-lived alpha emitter Ra-224; Studie zum Risiko von Spaetschaeden beim Menschen nach Inkorporation des kurzlebigen {alpha}-Strahlers Radium-224

    Energy Technology Data Exchange (ETDEWEB)

    Wick, R.R.; Nekolla, E.A.; Kellerer, A.M. [Muenchen Univ. (Germany). Strahlenbiologisches Inst.; Goessner, W. [Gesellschaft fuer Strahlen- und Umweltforschung mbH Muenchen, Neuherberg (Germany). Inst. fuer Pathologie

    2003-07-01

    An epidemiological study has been carried out at the GSF - National Research Center for Environment and Health - between 1948 and 1975, on 1460 ankylosing spondylitis (AS) patients. The aim of the study was to ascertain the late health effects suffered by these patients who had received repeated intravenous injections of the short lived {alpha}-emitter {sup 224}Ra. These patients have been followed together with a control group of 1323 ankylosing spondylitis patients not treated with radioactive drugs and/or X-rays. Causes of death have been ascertained for 842 exposed patients and 861 controls by the end of 2002. In the exposed group there has been a total of 219 malignant diseases and 206 cases among the controls. In particular, we observed 15 cases of leukaemia in the exposure group and 8 cases of leukaemia in the control group. Further subclassification of the leukaemias demonstrated a high increase of myeloid leukaemia in the exposure group (9 cases obs. vs. 2.5 cases exp.), and out of these especially the acute myeloid leukaemias (6 cases observed vs. 1.6 expected), whereas in the control group the observed cases are within the expected range (3 myeloid leukaemias vs. 2.6 cases). Out of these 6 cases of myeloid leukaemia, 3 cases have been observed at doses comparable to those of the currently applied {sup 224}Ra treatment with the preparation SpondylAT {sup registered}, in one case the {sup 224}Ra-dose was the 0.6fold, in another case 1.6fold, whereas in one case the total dose could not be verified exactly. The enhanced leukaemia incidence in our exposed group is in line with results from animal experiments in mice having been injected with bone seeking {alpha}-emitters given at low dose rates. (orig.) [German] Im Rahmen einer epidemiologischen Studie werden im GSF-Forschungszentrum 1460 Bechterew-Patienten beobachtet, die in den Jahren 1948 bis 1975 zur Behandlung ihrer Krankheit wiederholte intravenoese Injektionen von {sup 224}Ra erhalten haben. Daneben

  9. EFSA Panel on Food Contact Materials , Enzymes, Flavourings and Processing Aids (CEF); Scientific Opinion on Flavouring Group Evaluation 224 (FGE.224): Consideration of genotoxic potential for two α,β - unsaturated thiophenes from subgroup 5.2 of FGE.19 by EFSA

    DEFF Research Database (Denmark)

    Beltoft, Vibe Meister; Binderup, Mona-Lise; Lund, Pia;

    The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of two flavouring substances from subgroup 5.2 of FGE.19 in the Flavouring Group Evaluation 224 (FGE.224). The Flavour Industry has...

  10. Risk of leukaemia following intravenous treatment with {sup 224}Ra - results of a long term follow-up study of ankylosing spondylitis patients; Leukaemierisiko nach intravenoeser {sup 224}Ra-Behandlung - Ergebnisse einer Langzeitstudie an Bechterew-Patienten

    Energy Technology Data Exchange (ETDEWEB)

    Wick, R.R. [GSF - Forschungszentrum fuer Umwelt und Gesundheit Neuherberg GmbH, Oberschleissheim (Germany). Inst. fuer Strahlenbiologie; Chmelevsky, D. [GSF - Forschungszentrum fuer Umwelt und Gesundheit Neuherberg GmbH, Oberschleissheim (Germany). Inst. fuer Strahlenschutz; Goessner, W. [GSF - Forschungszentrum fuer Umwelt und Gesundheit Neuherberg GmbH, Oberschleissheim (Germany). Inst. fuer Pathologie

    1993-12-31

    In an epidemiological study of the somatic late effects risk following incorporation of a short lived {alpha}-emitter, 1473 ankylosing spondylitis patients treated with repeated intravenous injections of {sup 224}Ra in the years 1948 - 75, have been observed in the GSF. The usual therapeutic plan consisted of a total of 10 - 12 injections of 1.036 MBq (28 {mu}Ci) of {sup 224}Ra each, given at weekly intervals; this would result in an cumulative {alpha}-dose of 0.56 - 0.67 Gy to the marrow-free skeleton of a 70-kg-man (standard man). These patients have been followed together with a control group of ankylosing spondylitis patients not treated with radioactive drugs and/or X-rays. Until May 1993 (mean follow-up time 19.9 yr), 595 patients of the exposure group and 722 patients of the control group have died, causes of death have been ascertained for 578, resp. 668 patients. Among others we observed in the exposure group 10 cases of leukaemia (vs. 2.7 - 2.8 cases expected, p < 0.001) and 6 cases of leukaemia in the control group (vs. 3.3 - 3.5 exp., p = 0.14). Subclassification of the leukaemias shows a clear preference for chronic myeloid leukaemia (CML) in the exposure group (4 cases obs. vs. 0.8 cases exp., p = 0.009), whereas in the control group the observed cases of CML are within the range of expectancy. Similar observations have not been made in another group of patients, now observed by Spiess and co-workers, who have been treated at a higher dose/dose rate range. This increased incidence of leukaemias in our exposure group is in one line with results from animal experiments with bone seeking {alpha}-emitters given at low dose rates. The induction of myeloid leukaemia has been demonstrated in mice down to dose rates of only a few mGy/day also for {sup 239}Pu, an {alpha}-emitter which like {sup 224}Ra deposits preferentially on the bone surface. (orig.) [Deutsch] Im Rahmen einer epidemiologischen Studie zum somatischen Strahlenspaetschadenrisiko nach

  11. 四川地区224例全血细胞减少症回顾性分析%Retrospective analysis on 224 cases of pancytopenia in Sichuan area

    Institute of Scientific and Technical Information of China (English)

    杨银忠; 程文霞; 谢娜

    2014-01-01

    Objective To understand the etiopathogenesis of pancytopenia (PCP) in Sichuan area and to analyze the statistical difference in the aspects of sex ,season and age .Methods 224 cases of PCP were performed the etiological statistics on sex ,season and age by SPSS11 .0 .Results Among 224 cases of PCP ,46 cases(21% ) were megaloblastic anemia ,followed by 36 cases(16% ) of myelodysplastic syndromes (MDS) and 27 cases(12% ) of aplastic anemia(AA) .224 cases of PCP included 110 males(49 .10% ) and 114 females(50 .90% ) ,there was no statistical difference between sexes (P>0 .05) .In the seasons groups ,most of the patients went to see doctor and were diagnosed in the fourth quarter (32% ) and the first quarter was least (13% ) ,the difference between them had statistical significance(P<0 .05);In the age groups ,the age group of 45- <65 years old was the highest(36 .71% ) and the age group of less than 18 years was lowest(3 .57% ) ,the difference between them had statistical significance(P<0 .05) .Conclu-sion Megaloblastic anemia is the main etiology causing PCP in Sichuan area ,and the next is MDS and AA .The sex has no statisti-cal significance to the patients with PCP ,while the incidence rate in the aspects of season and age has statistical significance .%目的:了解四川地区全血细胞减少症(PC P )患者的病因,并分析其在性别、季度及年龄等方面有无统计学差异。方法对224例PC P患者进行病因统计,并按照性别、季度及年龄因素分组统计学分析。结果224例患者中,巨幼细胞性贫血最高占46例(21%),余依次骨髓增生异常综合征36例(16%),再生障碍性贫血27例(12%)等;224例患者中,男性110例(49.10%),女性114例(50.90%),两者比较差异无统计学意义( P>0.05);第4季度就医确诊患者最多(32%),第1季度最少(13%),两者比较差异有统计学意义( P<0.05);45~<65岁PC P

  12. Influence of Neutron Shell Closure (Nc=126) on Prescission Particle Emission of Fissioning Systems 216,224Th

    Institute of Scientific and Technical Information of China (English)

    叶巍

    2003-01-01

    The effect of neutron shell closure Nc = 126 on the prescission-particle emission of 216Th and 224Th nuclei is investigated within the framework of an extensive Smoluchowski equation. It is found that there is a large difference in the prescission neutron multiplicity for the two Th nuclei, indicating a strong shell effect in neutron emission. Moreover, shell effects on particle emission are also investigated as functions of excitation energy,angular momentum and nuclear viscosity. The results show that with increasing excitation energy shell effects in prefission neutron evolve from continual strength to gradual weakness. Both high angular momenta and low viscosity weaken the shell effects on the particle emission.

  13. Crystal structure of ethyl 2-(1H-benzimidazol-2-yl-2-[2-(4-nitrophenylhydrazinylidene]acetate

    Directory of Open Access Journals (Sweden)

    Mohamed Loughzail

    2015-04-01

    Full Text Available The title compound, C17H15N5O4, was obtained via the condensation of 3-ethoxy-2-[2-(4-nitrophenylhydrazono]-3-oxopropanoic acid with 1,2-diaminobenzene. In the molecule, the dihedral angles between the acetate group and the two aromatic subunits (benzimidazole and nitrophenylhydrazone are 7.35 (9 and 18.23 (9°, respectively. Intramolecular N—H...O and N—H...N contacts occur. In the crystal, C—H...O and N—H...O hydrogen bonds link the molecules into chains along the b-axis direction.

  14. Measurements of octupole collectivity in $^{220,222}$Rn and $^{222,224}$Ra using Coulomb excitation

    CERN Multimedia

    Kruecken, R; Larsen, A; Hurst, A M; Voulot, D; Grahn, T; Clement, E; Wadsworth, R; Gernhaeuser, R A; Siem, S; Huyse, M L; Iwanicki, J S

    2008-01-01

    We propose to exploit the unique capability of ISOLDE to provide post-accelerated $^{220,222}$Rn and $^{222,224}$Ra ion beams from the REX facility to enable the Coulomb excitation of the first 3$^{-}$ states in these nuclei. By measuring the $\\gamma$-ray yields of the E1 decays from the 3$^{-}$ state using the MINIBALL array we can obtain the transition matrix elements. This will give quantitative information about octupole correlations in these nuclei. We require 22 shifts to fulfil the aims of the experiment.

  15. Observation of Antibacterial Activity of Minocycline Against 224 Strains of Enterococci in vitro%米诺环素对224株肠球菌的体外抗菌活性研究

    Institute of Scientific and Technical Information of China (English)

    李仲兴; 王秀华; 杨敬芳; 时东彦; 李玮; 李继红

    2005-01-01

    目的:考察米诺环素对224株肠球菌的体外抗菌活性.方法:用二倍琼脂稀释法对224株肠球菌进行体外抗菌实验,并与多西环素、替考拉宁、万古霉素等进行抗菌效果对比.结果:米诺环素对169株粪肠球菌和51株屎肠球菌的MIC90分别为4和2μg·ml-1,而多西环素对169株粪肠球菌和51株屎肠球菌的MIC90则分别为4和4μg·ml-1.结论:米诺环素对肠球菌的抗菌效果与多西环素相似.

  16. Occurrence of radium-224, radium-226, and radium-228 in water of the unconfined Kirkwood-Cohansey aquifer system, southern New Jersey

    Science.gov (United States)

    Szabo, Zoltan; dePaul, Vincent T.; Kraemer, Thomas F.; Parsa, Bahman

    2005-01-01

    Water in the unconfined Kirkwood-Cohansey aquifer system in the New Jersey Coastal Plain contains elevated concentrations (above 3 pCi/L (picocuries per liter)) of the alpha-particle-emitting radionuclide radium-224. Previously, water from the aquifer system had been found to contain radium-226 and radium-228. This observation is of concern because the previously undetected presence of radium-224 may pose an additional, quantifiable health risk that currently is not accounted for by the Maximum Contaminant Level (MCL) of 5 pCi/L for combined radium (the sum of radium-226 plus radium-228 is termed 'combined radium') in drinking water. Water samples were collected from a regional network of 88 wells for determination of concentrations of radium-224, radium-226, and radium-228; gross alpha-particle activity; and concentrations of major ions and selected trace elements. Both gamma and alpha spectroscopic techniques were used to determine concentrations of radium-224, which ranged from activity of about 15 pCi/L (the MCL) 36 to 48 hours, respectively, after sample collection when ingrowth of radium-224 progeny radionuclides is considered, even with the unlikely assumption that no other alpha-particle-emitting radionuclide is present in the water. Concentrations of 3.4 to 3.7 pCi/L radium-224 result in a gross alpha-particle activity of 10 pCi/L 36 to 48 hours, respectively, after sample collection when ingrowth of Ra-224 progeny radionuclides is considered. In this latter case, it is possible that the summed alpha-particle activity from radium-226 present at a concentration less than or equal to 5 pCi/L (the MCL for combined radium) and from radium-224 present at a concentration about 3.4 pCi/L or greater may exceed the 15-pCi/L MCL for gross alpha-particle activity. In this study, gross alpha-particle activities were measured within 48 hours after sample collection and were found to exceed the MCL of 15 pCi/L in nearly half (43) of the 88 samples collected. The

  17. MicroRNA-224 is Readily Detectable in Urine of Individuals with Diabetes Mellitus and is a Potential Indicator of Beta-Cell Demise

    Directory of Open Access Journals (Sweden)

    Siobhán Bacon

    2015-06-01

    Full Text Available MicroRNA (miRNA are a class of non-coding, 19–25 nucleotide RNA critical for network-level regulation of gene expression. miRNA serve as paracrine signaling molecules. Using an unbiased array approach, we previously identified elevated levels of miR-224 and miR-103 to be associated with a monogenic form of diabetes; HNF1A-MODY. miR-224 is a novel miRNA in the field of diabetes. We sought to explore the role of miR-224 as a potential biomarker in diabetes, and whether such diabetes-associated-miRNA can also be detected in the urine of patients. Absolute levels of miR-224 and miR-103 were determined in the urine of n = 144 individuals including carriers of a HNF1A mutation, participants with type 1 diabetes mellitus (T1DM, type 2 diabetes mellitus (T2DM and normal controls. Expression levels were correlated with clinical and biochemical parameters. miR-224 was significantly elevated in the urine of carriers of a HNF1A mutation and participants with T1DM. miR-103 was highly expressed in urine across all diabetes cohorts when compared to controls. For both miR-224 and-103, we found a significant correlation between serum and urine levels (p < 0.01. We demonstrate that miRNA can be readily detected in the urine independent of clinical indices of renal dysfunction. We surmise that the differential expression levels of miR-224 in both HNF1A-MODY mutation carriers and T1DM may be an attempt to compensate for beta-cell demise.

  18. Purification, crystallization and preliminary crystallographic characterization of the α2,6-sialyltransferase from Photobacterium sp. JT-ISH-224

    Energy Technology Data Exchange (ETDEWEB)

    Okino, Nozomu; Kakuta, Yoshimitsu, E-mail: kakuta@agr.kyushu-u.ac.jp [Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581 (Japan); Kajiwara, Hitomi; Ichikawa, Masako; Takakura, Yoshimitsu [Glycotechnology Business Unit, Japan Tobacco Inc., 700 Higashibara, Iwata, Shizuoka 438-0802 (Japan); Ito, Makoto [Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581 (Japan); Yamamoto, Takeshi, E-mail: kakuta@agr.kyushu-u.ac.jp [Glycotechnology Business Unit, Japan Tobacco Inc., 700 Higashibara, Iwata, Shizuoka 438-0802 (Japan); Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581 (Japan)

    2007-08-01

    Crystallization of the α2,6-sialyltransferase from Photobacterium. Sialyltransferases transfer sialic acid from cytidine-5-monophospho-N-acetylneuraminic acid (CMP-NeuAc) to the nonreducing termini of the oligosaccharyl structures of various glycoproteins and glycolipids. The newly cloned α2,6-sialyltransferase from Photobacterium sp. JT-ISH-224 (from the Vibrionaceae family) is composed of two domains: an unknown N-terminal domain and a catalytic C-terminal domain which shares significant homology with the Pasteurella multocida multifunctional sialyltransferase. The putative mature form of JT-ISH-224 α2,6-sialyltransferase was overproduced in Escherichia coli, purified and crystallized using the hanging-drop vapour-diffusion method at 293 K. The crystal belonged to space group P3{sub 1}21 or P3{sub 2}21, with unit-cell parameters a = b = 90.29, c = 204.33 Å. X-ray diffraction data were collected to 2.5 Å resolution.

  19. Determination of Ra-224, Ra-226 and Ra-228 by gamma-ray spectrometry with radon retention

    International Nuclear Information System (INIS)

    Full text: The purpose of this work is to improve the determination, through gamma-ray spectrometry, of radium isotopes 228Ra, 226Ra and 224Ra in water. This improvement has been developed after the participation in the IAEA Proficiency test: 'Determination of radium and Uranium radionuclides in water' in December 2002, and applied to the same samples of this proficiency test. The aim of this new procedure is the determination of 228Ra, 226Ra and 224Ra activities by measuring the gamma-ray emissions of their decay products 228Ac, 214Pb and 212Pb, respectively. In the search for these activities, radiochemical separation of radium and lead are required. A coprecipitation method with stable barium and lead was carried out to obtain two different precipitates, both of them as sulphate. However emanation of unknown quantities of 222Rn and 220Rn is produced from the fine precipitate of the radium sulphate obtained which leads to wrong determinations of 224Ra and 226Ra activities. To avoid this radon exhalation effect the mentioned deposit, once the chemical yield has been calculated, is dissolved with EDTA and the resulting liquid incorporated into charcoal, and then it is dried and introduced into a suitable container. Afterwards the container is sealed and stored in a freezer. Different configurations of charcoal sizes and types as well as containers have been analysed. To perform this analysis several samples of those mentioned above containing 226Ra were used in order to test its equilibrium with the progeny, 214Pb and 214Bi, through gamma-ray spectrometry. The following results for contaminated samples with less than 50 Bq of 226Ra and using 30 ∼ 50 g of charcoal have been obtained: 1) There is a slight tendency to obtain better results using metallic containers rather than plastic ones 2) In general, specific activated charcoals, prepared to retain radon or noble gases allow better results than unspecific charcoals, but cannot be considered as better in a clear

  20. Oral health education to 224 cases of pregnancy women's oral health impact study%口腔健康教育对224例妊娠期妇女口腔健康影响研究

    Institute of Scientific and Technical Information of China (English)

    胡芳; 李健; 万燕燕

    2013-01-01

    Objective:To explore oral health education effect on pregnancy women's oral health.methods:224 patients were randomly divided into the treatment group 224 examples (for oral health education in patients with pregnancy) and the control group, 114 cases of oral health education (no). Observe two groups of pregnancy women's oral health.results:110 cases of late pregnancy women after oral health education during pregnancy gingivitis incidence of 3.63%, 1.81%incidence of tooth decay, periodontal disease incidence of 1.81%, wisdom tooth pericoronitis incidence of 2.72%. The total incidence of 10%.conclusion:Oral health education for women during pregnancy gingivitis and dental caries, periodontal disease, wisdom tooth pericoronitis incidence decreased significantly. Oral health education should pay more at ention to pregnant women.%目的:探讨口腔健康教育对妊娠期妇女口腔健康影响。方法:224例患者随机分为治疗组110例(对妊娠期患者进行口腔健康教育)与对照组114例(没有进行口腔健康教育)。观察两组妊娠期妇女口腔健康状况。结果:110例妊娠期妇女经过口腔健康教育后妊娠后期龈炎发病率3.63%,龋病发病率1.81%,牙周病发病率1.81%,智齿冠周炎发病率2.72%。总发病率10%。结论:口腔健康教育对妊娠期妇女牙龈炎、龋齿、牙周病、智齿冠周炎的发病率显著降低。孕妇口腔健康教育应当更加重视。

  1. Energy dependence of pi-zero production in Cu+Cu collisions at sqrt(s_NN) = 22.4, 62.4, and 200 GeV

    CERN Document Server

    Adare, A; Aidala, C; Ajitanand, N N; Akiba, Y; Al-Bataineh, H; Alexander, J; Aoki, K; Aphecetche, L; Armendariz, R; Aronson, S H; Asai, J; Atomssa, E T; Averbeck, R; Awes, T C; Azmoun, B; Babintsev, V; Bai, M; Baksay, G; Baksay, L; Baldisseri, Alberto; Barish, K N; Barnes, P D; Bassalleck, B; Basye, A T; Bathe, S; Batsouli, S; Baublis, V; Baumann, C; Bazilevsky, A; Belikov, S; Bennett, R; Berdnikov, A; Berdnikov, Y; Bickley, A A; Boissevain, J G; Borel, H; Boyle, K; Brooks, M L; Büsching, H; Bumazhnov, V; Bunce, G; Butsyk, S; Camacho, C M; Campbell, S; Chang, B S; Chang, W C; Charvet, J L; Chernichenko, S; Chiba, J; Chi, C Y; Chiu, M; Choi, I J; Choudhury, R K; Chujo, T; Chung, P; Churyn, A; Cianciolo, V; Citron, Z; Cleven, C R; Cole, B A; Comets, M P; Constantin, P; Csanad, M; Csrgo, T; Dahms, T; Dairaku, S; Das, K; Dávid, G; Deaton, M B; Dehmelt, K; Delagrange, H; Denisov, A; d'Enterria, D; Deshpande, A; Desmond, E J; Dietzsch, O; Dion, A; Donadelli, M; Drapier, O; Drees, A; Drees, K A; Dubey, A K; Durum, A; Dutta, D; Dzhordzhadze, V; Efremenko, Yu V; Egdemir, J; Ellinghaus, F; Emam, W S; Engelmore, T; Enokizono, A; Enyo, H; Esumi, S; Eyser, K O; Fadem, B; Fields, D E; Finger, M; Finger, M; Fleuret, F; Fokin, S L; Fraenkel, Zeev; Frantz, J E; Franz, A; Frawley, A D; Fujiwara, K; Fukao, Y; Fusayasu, T; Gadrat, S; Garishvili, I; Glenn, A; Gong, H; Gonin, M; Gosset, J; Goto, Y; Granier de Cassagnac, R; Grau, N; Greene, S V; Grosse-Perdekamp, M; Gunji, T; Gustafsson, H; Hachiya, T; Hadj Henni, A; Haegemann, C; Haggerty, J S; Hamagaki, H; Han, AR; Harada, H; Hartouni, E P; Haruna, K; Haslum, E; Hayano, R; Heffner, M; Hemmick, T K; Hester, T; He, X; Hiejima, H; Hill, J C; Hobbs, R; Hohlmann, M; Holzmann, W; Homma, K; Hong, B; Horaguchi, T; Hornback, D; Huang, S; Ichihara, T; Ichimiya, R; Ikeda, Y; Imai, K; Imrek, J; Inaba, M; Inoue, Y; Isenhower, D; Isenhower, L; Ishihara, M; Isobe, T; Issah, M; Isupov, A; Ivanischev, D; Jacak, B V; Jia, J; Jin, J; Jinnouchi, O; Johnson, B M; Joo, K S; Jouan, D; Kajihara, F; Kametani, S; Kamihara, N; Kamin, J; Kaneta, M; Kang, J H; Kanou, H; Kapustinsky, J; Kawall, D; Kazantsev, A V; Khanzadeev, A; Kijima, K M; Kikuchi, J; Kim, B I; Kim, D H; Kim, D J; Kim, E; Kim, S H; Kinney, E; Kiriluk, K; Kiss, A; Kistenev, E; Kiyomichi, A; Klay, J; Klein-Bösing, C; Kochenda, L; Kochetkov, V; Komkov, B; Konno, M; Koster, J; Kotchetkov, D; Kozlov, A; Krl, A; Kravitz, A; Kubart, J; Kunde, G J; Kurihara, N; Kurita, K; Kurosawa, M; Kweon, M J; Kwon, Y; Kyle, G S; Lacey, R; Lai, Y S; Lai, Y S; Lajoie, J G; Layton, D; Lebedev, A; Lee, D M; Lee, K B; Lee, M K; Lee, T; Leitch, M J; Leite, M A L; Lenzi, B; Liebing, P; Lika, T; Litvinenko, A; Liu, H; Liu, M X; Li, X; Love, B; Lynch, D; Maguire, C F; Makdisi, Y I; Malakhov, A; Malik, M D; Man'ko, V I; Mannel, E; Mao, Y; Maek, L; Masui, H; Matathias, F; McCumber, M; McGaughey, P L; Means, N; Meredith, B; Miake, Y; Mike, P; Miki, K; Miller, T E; Milov, A; Mioduszewski, S; Mishra, M; Mitchell, J T; Mitrovski, M; Mohanty, A K; Morino, Y; Morreale, A; Morrison, D P; Moukhanova, T V; Mukhopadhyay, D; Murata, J; Nagamiya, S; Nagata, Y; Nagle, J L; Naglis, M; Nagy, M I; Nakagawa, I; Nakamiya, Y; Nakamura, T; Nakano, K; Newby, J; Nguyen, M; Niita, T; Norman, B E; Nouicer, R; Nyanin, A S; O'Brien, E; Oda, S X; Ogilvie, C A; Ohnishi, H; Okada, H; Okada, K; Oka, M; Omiwade, O O; Onuki, Y; Oskarsson, A; Ouchida, M; Ozawa, K; Pak, R; Pal, D; Palounek, A P T; Pantuev, V; Papavassiliou, V; Park, J; Park, W J; Pate, S F; Pei, H; Peng, J C; Pereira, H; Peresedov, V; Peressounko, D Yu; Pinkenburg, C; Purschke, M L; Purwar, A K; Qu, H; Rak, J; Rakotozafindrabe, A; Ravinovich, I; Read, K F; Rembeczki, S; Reuter, M; Reygers, K; Riabov, V; Riabov, Y; Roach, D; Roche, G; Rolnick, S D; Romana, A; Rosati, M; Rosendahl, S S E; Rosnet, P; Rukoyatkin, P; Ruika, P; Rykov, V L; Sahlmueller, B; Saitô, N; Sakaguchi, T; Sakai, S; Sakashita, K; Sakata, H; Samsonov, V; Sato, S; Sato, T; Sawada, S; Sedgwick, K; Seele, J; Seidl, R; Semenov, A Yu; Semenov, V; Seto, R; Sharma, D; Shein, I; Shevel, A; Shibata, T A; Shigaki, K; Shimomura, M; Shoji, K; Shukla, P; Sickles, A; Silva, C L; Silvermyr, D; Silvestre, C; Sim, K S; Singh, B K; Singh, C P; Singh, V; Skutnik, S; Sluneka, M; Soldatov, A; Soltz, R A; Sondheim, W E; Sørensen, S P; Sourikova, I V; Staley, F; Stankus, P W; Stenlund, E; Stepanov, M; Ster, A; Stoll, S P; Sugitate, T; Suire, C; Sukhanov, A; Sziklai, J; Tabaru, T; Takagi, S; Takagui, E M; Taketani, A; Tanabe, R; Tanaka, Y; Tanida, K; Tannenbaum, M J; Taranenko, A; Tarjn, P; Themann, H; Thomas, T L; Togawa, M; Toia, A; Tojo, J; Tomaek, L; Tomita, Y; Torii, H; Towell, R S; Tram, V-N; Tserruya, Itzhak; Tsuchimoto, Y; Vale, C; Valle, H; van Hecke, H W; Veicht, A; Velkovska, J; Vertesi, R; Vinogradov, A A; Virius, M; Vrba, V; Vznuzdaev, E; Wagner, M; Walker, D; Wang, X R; Watanabe, Y

    2008-01-01

    Neutral pion transverse momentum (pT) spectra at mid-rapidity (|y| < 0.35) were measured in Cu+Cu collisions at \\sqrt s_NN = 22.4, 62.4, and 200 GeV. Relative to pi -zero yields in p+p collisions scaled by the number of inelastic nucleon-nucleon collisions (Ncoll) at the respective energies, the pi-zero yields for pT \\ge 2 GeV/c in central Cu+Cu collisions at 62.4 and 200 GeV are suppressed, whereas an enhancement is observed at 22.4 GeV. A comparison with a jet quenching model suggests that final state parton energy loss dominates in central Cu+Cu collisions at 62.4 GeV and 200 GeV, while the enhancement at 22.4 GeV is consistent with nuclear modifications in the initial state alone.

  2. Onset of pi(0) suppression studied in Cu+Cu collisions at sqrt S NN=22.4, 62.4, and 200 GeV.

    Science.gov (United States)

    Adare, A; Afanasiev, S; Aidala, C; Ajitanand, N N; Akiba, Y; Al-Bataineh, H; Alexander, J; Aoki, K; Aphecetche, L; Armendariz, R; Aronson, S H; Asai, J; Atomssa, E T; Averbeck, R; Awes, T C; Azmoun, B; Babintsev, V; Bai, M; Baksay, G; Baksay, L; Baldisseri, A; Barish, K N; Barnes, P D; Bassalleck, B; Basye, A T; Bathe, S; Batsouli, S; Baublis, V; Baumann, C; Bazilevsky, A; Belikov, S; Bennett, R; Berdnikov, A; Berdnikov, Y; Bickley, A A; Boissevain, J G; Borel, H; Boyle, K; Brooks, M L; Buesching, H; Bumazhnov, V; Bunce, G; Butsyk, S; Camacho, C M; Campbell, S; Chang, B S; Chang, W C; Charvet, J-L; Chernichenko, S; Chiba, J; Chi, C Y; Chiu, M; Choi, I J; Choudhury, R K; Chujo, T; Chung, P; Churyn, A; Cianciolo, V; Citron, Z; Cleven, C R; Cole, B A; Comets, M P; Constantin, P; Csanád, M; Csörgo, T; Dahms, T; Dairaku, S; Das, K; David, G; Deaton, M B; Dehmelt, K; Delagrange, H; Denisov, A; d'Enterria, D; Deshpande, A; Desmond, E J; Dietzsch, O; Dion, A; Donadelli, M; Drapier, O; Drees, A; Drees, K A; Dubey, A K; Durum, A; Dutta, D; Dzhordzhadze, V; Efremenko, Y V; Egdemir, J; Ellinghaus, F; Emam, W S; Engelmore, T; Enokizono, A; En'yo, H; Esumi, S; Eyser, K O; Fadem, B; Fields, D E; Finger, M; Finger, M; Fleuret, F; Fokin, S L; Fraenkel, Z; Frantz, J E; Franz, A; Frawley, A D; Fujiwara, K; Fukao, Y; Fusayasu, T; Gadrat, S; Garishvili, I; Glenn, A; Gong, H; Gonin, M; Gosset, J; Goto, Y; Granier de Cassagnac, R; Grau, N; Greene, S V; Grosse Perdekamp, M; Gunji, T; Gustafsson, H-A; Hachiya, T; Hadj Henni, A; Haegemann, C; Haggerty, J S; Hamagaki, H; Han, R; Harada, H; Hartouni, E P; Haruna, K; Haslum, E; Hayano, R; Heffner, M; Hemmick, T K; Hester, T; He, X; Hiejima, H; Hill, J C; Hobbs, R; Hohlmann, M; Holzmann, W; Homma, K; Hong, B; Horaguchi, T; Hornback, D; Huang, S; Ichihara, T; Ichimiya, R; Ikeda, Y; Imai, K; Imrek, J; Inaba, M; Inoue, Y; Isenhower, D; Isenhower, L; Ishihara, M; Isobe, T; Issah, M; Isupov, A; Ivanischev, D; Jacak, B V; Jia, J; Jin, J; Jinnouchi, O; Johnson, B M; Joo, K S; Jouan, D; Kajihara, F; Kametani, S; Kamihara, N; Kamin, J; Kaneta, M; Kang, J H; Kanou, H; Kapustinsky, J; Kawall, D; Kazantsev, A V; Kempel, T; Khanzadeev, A; Kijima, K M; Kikuchi, J; Kim, B I; Kim, D H; Kim, D J; Kim, E; Kim, S H; Kinney, E; Kiriluk, K; Kiss, A; Kistenev, E; Kiyomichi, A; Klay, J; Klein-Boesing, C; Kochenda, L; Kochetkov, V; Komkov, B; Konno, M; Koster, J; Kotchetkov, D; Kozlov, A; Král, A; Kravitz, A; Kubart, J; Kunde, G J; Kurihara, N; Kurita, K; Kurosawa, M; Kweon, M J; Kwon, Y; Kyle, G S; Lacey, R; Lai, Y-S; Lai, Y S; Lajoie, J G; Layton, D; Lebedev, A; Lee, D M; Lee, K B; Lee, M K; Lee, T; Leitch, M J; Leite, M A L; Lenzi, B; Liebing, P; Liska, T; Litvinenko, A; Liu, H; Liu, M X; Li, X; Love, B; Lynch, D; Maguire, C F; Makdisi, Y I; Malakhov, A; Malik, M D; Manko, V I; Mannel, E; Mao, Y; Masek, L; Masui, H; Matathias, F; McCumber, M; McGaughey, P L; Means, N; Meredith, B; Miake, Y; Mikes, P; Miki, K; Miller, T E; Milov, A; Mioduszewski, S; Mishra, M; Mitchell, J T; Mitrovski, M; Mohanty, A K; Morino, Y; Morreale, A; Morrison, D P; Moukhanova, T V; Mukhopadhyay, D; Murata, J; Nagamiya, S; Nagata, Y; Nagle, J L; Naglis, M; Nagy, M I; Nakagawa, I; Nakamiya, Y; Nakamura, T; Nakano, K; Newby, J; Nguyen, M; Niita, T; Norman, B E; Nouicer, R; Nyanin, A S; O'Brien, E; Oda, S X; Ogilvie, C A; Ohnishi, H; Okada, H; Okada, K; Oka, M; Omiwade, O O; Onuki, Y; Oskarsson, A; Ouchida, M; Ozawa, K; Pak, R; Pal, D; Palounek, A P T; Pantuev, V; Papavassiliou, V; Park, J; Park, W J; Pate, S F; Pei, H; Peng, J-C; Pereira, H; Peresedov, V; Peressounko, D Yu; Pinkenburg, C; Purschke, M L; Purwar, A K; Qu, H; Rak, J; Rakotozafindrabe, A; Ravinovich, I; Read, K F; Rembeczki, S; Reuter, M; Reygers, K; Riabov, V; Riabov, Y; Roach, D; Roche, G; Rolnick, S D; Romana, A; Rosati, M; Rosendahl, S S E; Rosnet, P; Rukoyatkin, P; Ruzicka, P; Rykov, V L; Sahlmueller, B; Saito, N; Sakaguchi, T; Sakai, S; Sakashita, K; Sakata, H; Samsonov, V; Sato, S; Sato, T; Sawada, S; Sedgwick, K; Seele, J; Seidl, R; Semenov, A Yu; Semenov, V; Seto, R; Sharma, D; Shein, I; Shevel, A; Shibata, T-A; Shigaki, K; Shimomura, M; Shoji, K; Shukla, P; Sickles, A; Silva, C L; Silvermyr, D; Silvestre, C; Sim, K S; Singh, B K; Singh, C P; Singh, V; Skutnik, S; Slunecka, M; Soldatov, A; Soltz, R A; Sondheim, W E; Sorensen, S P; Sourikova, I V; Staley, F; Stankus, P W; Stenlund, E; Stepanov, M; Ster, A; Stoll, S P; Sugitate, T; Suire, C; Sukhanov, A; Sziklai, J; Tabaru, T; Takagi, S; Takagui, E M; Taketani, A; Tanabe, R; Tanaka, Y; Tanida, K; Tannenbaum, M J; Taranenko, A; Tarján, P; Themann, H; Thomas, T L; Togawa, M; Toia, A; Tojo, J; Tomásek, L; Tomita, Y; Torii, H; Towell, R S; Tram, V-N; Tserruya, I; Tsuchimoto, Y; Vale, C; Valle, H; vanHecke, H W; Veicht, A; Velkovska, J; Vertesi, R; Vinogradov, A A; Virius, M; Vrba, V; Vznuzdaev, E; Wagner, M; Walker, D

    2008-10-17

    Neutral pion transverse momentum (p(T)) spectra at midrapidity (|y| less than or approximately 0.35) were measured in Cu+Cu collisions at sqrt[s(NN)]=22.4, 62.4, and 200 GeV. Relative to pi_(0) yields in p+p collisions scaled by the number of inelastic nucleon-nucleon collisions (N(coll) the pi_(0) yields for p(T) more than or approximately 2 GeV/c in central Cu+Cu collisions are suppressed at 62.4 and 200 GeV whereas an enhancement is observed at 22.4 GeV. A comparison with a jet-quenching model suggests that final state parton energy loss dominates in central Cu+Cu collisions at 62.4 and 200 GeV, while the enhancement at 22.4 GeV is consistent with nuclear modifications in the initial state alone.

  3. Onset of pi(0) suppression studied in Cu+Cu collisions at sqrt S NN=22.4, 62.4, and 200 GeV.

    Science.gov (United States)

    Adare, A; Afanasiev, S; Aidala, C; Ajitanand, N N; Akiba, Y; Al-Bataineh, H; Alexander, J; Aoki, K; Aphecetche, L; Armendariz, R; Aronson, S H; Asai, J; Atomssa, E T; Averbeck, R; Awes, T C; Azmoun, B; Babintsev, V; Bai, M; Baksay, G; Baksay, L; Baldisseri, A; Barish, K N; Barnes, P D; Bassalleck, B; Basye, A T; Bathe, S; Batsouli, S; Baublis, V; Baumann, C; Bazilevsky, A; Belikov, S; Bennett, R; Berdnikov, A; Berdnikov, Y; Bickley, A A; Boissevain, J G; Borel, H; Boyle, K; Brooks, M L; Buesching, H; Bumazhnov, V; Bunce, G; Butsyk, S; Camacho, C M; Campbell, S; Chang, B S; Chang, W C; Charvet, J-L; Chernichenko, S; Chiba, J; Chi, C Y; Chiu, M; Choi, I J; Choudhury, R K; Chujo, T; Chung, P; Churyn, A; Cianciolo, V; Citron, Z; Cleven, C R; Cole, B A; Comets, M P; Constantin, P; Csanád, M; Csörgo, T; Dahms, T; Dairaku, S; Das, K; David, G; Deaton, M B; Dehmelt, K; Delagrange, H; Denisov, A; d'Enterria, D; Deshpande, A; Desmond, E J; Dietzsch, O; Dion, A; Donadelli, M; Drapier, O; Drees, A; Drees, K A; Dubey, A K; Durum, A; Dutta, D; Dzhordzhadze, V; Efremenko, Y V; Egdemir, J; Ellinghaus, F; Emam, W S; Engelmore, T; Enokizono, A; En'yo, H; Esumi, S; Eyser, K O; Fadem, B; Fields, D E; Finger, M; Finger, M; Fleuret, F; Fokin, S L; Fraenkel, Z; Frantz, J E; Franz, A; Frawley, A D; Fujiwara, K; Fukao, Y; Fusayasu, T; Gadrat, S; Garishvili, I; Glenn, A; Gong, H; Gonin, M; Gosset, J; Goto, Y; Granier de Cassagnac, R; Grau, N; Greene, S V; Grosse Perdekamp, M; Gunji, T; Gustafsson, H-A; Hachiya, T; Hadj Henni, A; Haegemann, C; Haggerty, J S; Hamagaki, H; Han, R; Harada, H; Hartouni, E P; Haruna, K; Haslum, E; Hayano, R; Heffner, M; Hemmick, T K; Hester, T; He, X; Hiejima, H; Hill, J C; Hobbs, R; Hohlmann, M; Holzmann, W; Homma, K; Hong, B; Horaguchi, T; Hornback, D; Huang, S; Ichihara, T; Ichimiya, R; Ikeda, Y; Imai, K; Imrek, J; Inaba, M; Inoue, Y; Isenhower, D; Isenhower, L; Ishihara, M; Isobe, T; Issah, M; Isupov, A; Ivanischev, D; Jacak, B V; Jia, J; Jin, J; Jinnouchi, O; Johnson, B M; Joo, K S; Jouan, D; Kajihara, F; Kametani, S; Kamihara, N; Kamin, J; Kaneta, M; Kang, J H; Kanou, H; Kapustinsky, J; Kawall, D; Kazantsev, A V; Kempel, T; Khanzadeev, A; Kijima, K M; Kikuchi, J; Kim, B I; Kim, D H; Kim, D J; Kim, E; Kim, S H; Kinney, E; Kiriluk, K; Kiss, A; Kistenev, E; Kiyomichi, A; Klay, J; Klein-Boesing, C; Kochenda, L; Kochetkov, V; Komkov, B; Konno, M; Koster, J; Kotchetkov, D; Kozlov, A; Král, A; Kravitz, A; Kubart, J; Kunde, G J; Kurihara, N; Kurita, K; Kurosawa, M; Kweon, M J; Kwon, Y; Kyle, G S; Lacey, R; Lai, Y-S; Lai, Y S; Lajoie, J G; Layton, D; Lebedev, A; Lee, D M; Lee, K B; Lee, M K; Lee, T; Leitch, M J; Leite, M A L; Lenzi, B; Liebing, P; Liska, T; Litvinenko, A; Liu, H; Liu, M X; Li, X; Love, B; Lynch, D; Maguire, C F; Makdisi, Y I; Malakhov, A; Malik, M D; Manko, V I; Mannel, E; Mao, Y; Masek, L; Masui, H; Matathias, F; McCumber, M; McGaughey, P L; Means, N; Meredith, B; Miake, Y; Mikes, P; Miki, K; Miller, T E; Milov, A; Mioduszewski, S; Mishra, M; Mitchell, J T; Mitrovski, M; Mohanty, A K; Morino, Y; Morreale, A; Morrison, D P; Moukhanova, T V; Mukhopadhyay, D; Murata, J; Nagamiya, S; Nagata, Y; Nagle, J L; Naglis, M; Nagy, M I; Nakagawa, I; Nakamiya, Y; Nakamura, T; Nakano, K; Newby, J; Nguyen, M; Niita, T; Norman, B E; Nouicer, R; Nyanin, A S; O'Brien, E; Oda, S X; Ogilvie, C A; Ohnishi, H; Okada, H; Okada, K; Oka, M; Omiwade, O O; Onuki, Y; Oskarsson, A; Ouchida, M; Ozawa, K; Pak, R; Pal, D; Palounek, A P T; Pantuev, V; Papavassiliou, V; Park, J; Park, W J; Pate, S F; Pei, H; Peng, J-C; Pereira, H; Peresedov, V; Peressounko, D Yu; Pinkenburg, C; Purschke, M L; Purwar, A K; Qu, H; Rak, J; Rakotozafindrabe, A; Ravinovich, I; Read, K F; Rembeczki, S; Reuter, M; Reygers, K; Riabov, V; Riabov, Y; Roach, D; Roche, G; Rolnick, S D; Romana, A; Rosati, M; Rosendahl, S S E; Rosnet, P; Rukoyatkin, P; Ruzicka, P; Rykov, V L; Sahlmueller, B; Saito, N; Sakaguchi, T; Sakai, S; Sakashita, K; Sakata, H; Samsonov, V; Sato, S; Sato, T; Sawada, S; Sedgwick, K; Seele, J; Seidl, R; Semenov, A Yu; Semenov, V; Seto, R; Sharma, D; Shein, I; Shevel, A; Shibata, T-A; Shigaki, K; Shimomura, M; Shoji, K; Shukla, P; Sickles, A; Silva, C L; Silvermyr, D; Silvestre, C; Sim, K S; Singh, B K; Singh, C P; Singh, V; Skutnik, S; Slunecka, M; Soldatov, A; Soltz, R A; Sondheim, W E; Sorensen, S P; Sourikova, I V; Staley, F; Stankus, P W; Stenlund, E; Stepanov, M; Ster, A; Stoll, S P; Sugitate, T; Suire, C; Sukhanov, A; Sziklai, J; Tabaru, T; Takagi, S; Takagui, E M; Taketani, A; Tanabe, R; Tanaka, Y; Tanida, K; Tannenbaum, M J; Taranenko, A; Tarján, P; Themann, H; Thomas, T L; Togawa, M; Toia, A; Tojo, J; Tomásek, L; Tomita, Y; Torii, H; Towell, R S; Tram, V-N; Tserruya, I; Tsuchimoto, Y; Vale, C; Valle, H; vanHecke, H W; Veicht, A; Velkovska, J; Vertesi, R; Vinogradov, A A; Virius, M; Vrba, V; Vznuzdaev, E; Wagner, M; Walker, D; Wang, X R; Watanabe, Y; Wei, F; Wessels, J; White, S N; Winter, D; Woody, C L; Wysocki, M; Xie, W; Yamaguchi, Y L; Yamaura, K; Yang, R; Yanovich, A; Yasin, Z; Ying, J; Yokkaichi, S; Young, G R; Younus, I; Yushmanov, I E; Zajc, W A; Zaudtke, O; Zhang, C; Zhou, S; Zimányi, J; Zolin, L

    2008-10-17

    Neutral pion transverse momentum (p(T)) spectra at midrapidity (|y| less than or approximately 0.35) were measured in Cu+Cu collisions at sqrt[s(NN)]=22.4, 62.4, and 200 GeV. Relative to pi_(0) yields in p+p collisions scaled by the number of inelastic nucleon-nucleon collisions (N(coll) the pi_(0) yields for p(T) more than or approximately 2 GeV/c in central Cu+Cu collisions are suppressed at 62.4 and 200 GeV whereas an enhancement is observed at 22.4 GeV. A comparison with a jet-quenching model suggests that final state parton energy loss dominates in central Cu+Cu collisions at 62.4 and 200 GeV, while the enhancement at 22.4 GeV is consistent with nuclear modifications in the initial state alone. PMID:18999660

  4. Analysis of clinical characteristics and drug resistance of 224 strains of Acinetobacter baumannii infection%224例鲍曼不动杆菌感染的临床特征及耐药性分析

    Institute of Scientific and Technical Information of China (English)

    徐薛芬; 徐爱晖

    2013-01-01

    目的 了解我院224例鲍曼不动杆菌感染的临床特征及耐药性.方法 采用常规方法进行细菌培养、菌株鉴定及药敏检测.结果 201名患者共分离出224株鲍曼不动杆菌,患者主要集中在ICU(33.8%)、外科(25.9%)、呼吸内科(14.4%)、骨科(6.1%),基础疾病以呼吸系统疾病(64.2%)、心血管系统疾病(30.8%)、神经系统疾病(29.8%)及糖尿病(22.9%)多见,与手术治疗及有创检查治疗(56.7%)、联合使用≥2种抗生素(80.6%)及使用时间≥15天(38.8%)可能存在相关性.224株鲍曼不动杆菌对米诺环素敏感性最高(66.1%),对美罗培南、氨苄西林/舒巴坦、头孢哌酮/舒巴坦敏感性超过55%.结论 鲍曼不动杆菌感染与患者有基础疾病、有创性检查治疗及使用广谱抗生素及时间过长有关,其耐药情况严重,多重耐药及泛耐药菌株日益增多,目前对米诺环素、舒巴坦、碳青酶烯类抗生素仍保持相对敏感性,临床应根据药敏结果合理选择使用抗生素.%Objective To investigate the clinical charateristics of infection of 224 Acinetobacter baumannii strains, and to analyze drug resistance of Acinetobacter baumannii strains. Methods The isolation of the bacterium was conducted according to the microorganical method of CLSI ( Clinical and Laboratory Standards Institute ). American DATE Company MicroScan Walkway-40 automatic analyzer was applied to identification and drug susceptibility test. Drug resistance was calculated with WH0NET5. 4 soitware. Results A total of 224 strains of Acinetobacter baumannii were isolated from 201 patients. The patients were mainly from ICU( intensive care uint) ( 33. 8% ), department of surgery ( 25. 9% ), department of respiratory medicine ( 14. 4% ), department of orthopedics ( 6. 1% ). Common underlying diseases were pulmonary diseases ( 64. 2% ), cardiovascular diseases ( 30. 8% ), diseases of nervous system ( 29. 8% ) and diabetes ( 22. 9% ). 56. 7% of the patients had

  5. Study of the reaction anti pp → p+X at 22.4 GeV/c

    International Nuclear Information System (INIS)

    Some features of the reaction anti pp→p+X at 22.4 GeV/c are investigated using the statistically separated spectra of charged particles in the whole phase space. A change from the general trend in the behayiour of the average associated multiplicity at missing mass Msub(X)sup(2) approximately equal to 20 GeVsup(2) is found. This may be connected with the clusterization process, for instance, heavy resonance production. A confirmation of clusterization for Msub(x)sup(2)>=20GeVsup(2) is made when analyzing the rapidity gap distributions. The maxima of the structure functions are shifted towards larger missing masses with increasing multiplicity. It is shown that quark-parton model describes qualitatively the one-particle structure functions but does not reproduce the elusterization

  6. Electroacupuncture Combined with Flash Cupping for Treatment of Peripheral Facial Paralysis ——A Report of 224 Cases

    Institute of Scientific and Technical Information of China (English)

    Tian Jianqi; Duan Shumin

    2007-01-01

    Objective: To observe the therapeutic effects of electroacupuncture plus flash cupping for peripheral facial paralysis. Method: The main points used were Jingming (BL 1), Yangbai (GB 14) and Sibai (ST 2) with the adjunct points selected according to the syndrome differentiation. The routine acupuncture,electroacupuncture and flash cupping were used to treat 224 cases of peripheral facial paralysis. Result:The total effective rate was 96%. Conclusion: Acupuncture can regulate the flow of blood and qi and dredge the channels and collaterals; the pulse electrotherapy can enhance excitation of the muscular tissues;and the flash cupping can make the local tissues to be in a state of high oxygen supply, benefiting blood circulation. The synergistic action of electroacupuncture and flash cupping can raise the therapeutic effect.

  7. Synthesis, photo-physical and DFT studies of ESIPT inspired novel 2-(2',4'-dihydroxyphenyl) benzimidazole, benzoxazole and benzothiazole.

    Science.gov (United States)

    Patil, Vikas S; Padalkar, Vikas S; Tathe, Abhinav B; Gupta, Vinod D; Sekar, N

    2013-09-01

    Novel ESIPT inspired benzimidazole, benzoxazole and benzothiazole were synthesized from 2,4-dihydroxy benzoic acid and 1,2-phenelenediamine, 2-aminophenol, and 2-aminothiophenol respectively. The synthesized 2-(2',4'-dihydroxyphenyl) benzimidazole, benzoxazole and benzothiazole are fluorescent and the emission characteristic are very sensitive to the micro-environment. They show a single absorption and dual emission with large Stokes shift originating from excited state intramolecular proton transfer. The absorption-emission characteristics of all these compounds are studied as a function of pH. The change in the electronic transition, energy levels, and orbital diagrams of synthesized compounds were investigated by the molecular orbital calculation and were correlated with the experimental spectral emission. Experimental absorption and emission wavelengths are in good agreement with those predicted using the Density Functional Theory (DFT) and Time-Dependent Density Functional Theory (TD-DFT) [B3LYP/6-31G(d)].

  8. Sediment-water column fluxes of carbon, oxygen and nutrients in Bedford Basin, Nova Scotia, inferred from 224Ra measurements

    Directory of Open Access Journals (Sweden)

    E. Horne

    2013-01-01

    Full Text Available Exchanges between sediment pore waters and the overlying water column play a significant role in the chemical budgets of many important chemical constituents. Direct quantification of such benthic fluxes requires explicit knowledge of the sediment properties and biogeochemistry. Alternatively, changes in water-column properties near the sediment-water interface can be exploited to gain insight into the sediment biogeochemistry and benthic fluxes. Here, we apply a 1-D diffusive mixing model to near-bottom water-column profiles of 224Ra activity in order to yield vertical eddy diffusivities (KZ, based upon which we assess the diffusive exchange of dissolved inorganic carbon (DIC, nutrients and oxygen (O2, across the sediment-water interface in a coastal inlet, Bedford Basin, Nova Scotia, Canada. Numerical model results are consistent with the assumptions regarding a constant, single benthic source of 224Ra, the lack of mixing by advective processes, and a predominantly benthic source and sink of DIC and O2, respectively, with minimal water-column respiration in the deep waters of Bedford Basin. Near-bottom observations of DIC, O2 and nutrients provide flux ratios similar to Redfield values, suggesting that benthic respiration of primarily marine organic matter is the dominant driver. Furthermore, a relative deficit of nitrate in the observed flux ratios indicates that denitrification also plays a role in the oxidation of organic matter, although its occurrence was not strong enough to allow us to detect the corresponding AT fluxes out of the sediment. Finally, comparison with other carbon sources reveal the observed benthic DIC release as a significant contributor to the Bedford Basin carbon system.

  9. Local Control of Lung Derived Tumors by Diffusing Alpha-Emitting Atoms Released From Intratumoral Wires Loaded With Radium-224

    International Nuclear Information System (INIS)

    Purpose: Diffusing alpha-emitters radiation therapy (DART) is a new form of brachytherapy enabling the treatment of solid tumors with alpha radiation. The present study examines the antitumoral effects resulting from the release of alpha emitting radioisotopes into solid lung carcinoma (LL2, A427, and NCI-H520). Methods and Materials: An in vitro setup tested the dose-dependent killing of tumor cells exposed to alpha particles. In in vivo studies, radioactive wires (0.3 mm diameter, 5 mm long) with 224Ra activities in the range of 21-38 kBq were inserted into LL/2 tumors in C57BL/6 mice and into human-derived A427 or NCI-H520 tumors in athymic mice. The efficacy of the short-lived daughters of 224Ra to produce tumor growth retardation and prolong life was assessed, and the spread of radioisotopes inside tumors was measured using autoradiography. Results: The insertion of a single DART wire into the center of 6- to 7-mm tumors had a pronounced retardation effect on tumor growth, leading to a significant inhibition of 49% (LL2) and 93% (A427) in tumor development and prolongations of 48% (LL2) in life expectancy. In the human model, more than 80% of the treated tumors disappeared or shrunk. Autoradiographic analysis of the treated sectioned tissue revealed the intratumoral distribution of the radioisotopes, and histological analysis showed corresponding areas of necrosis. In vitro experiments demonstrated a dose-dependent killing of tumors cells exposed to alpha particles. Conclusions: Short-lived diffusing alpha-emitters produced tumor growth retardation and increased survival in mice bearing lung tumor implants. These results justify further investigations with improved dose distributions.

  10. Phase Conjugated Twin Waves in 8×21×224Gbit/s DP-16QAM Multi-core Fiber Transmission

    DEFF Research Database (Denmark)

    Asif, Rameez; Ye, Feihong; Morioka, Toshio

    2014-01-01

    Efficient suppression of non-linear interactions has been n umerically analyzed via phase conjugated twin waves in 8 × 21 × 224 Gbit/s multi-core fiber transmission. Results show a Q-factor improvement of 2.8 dB, consequently doubling the transmission distance....

  11. Nonlinear Equalization in 40/112/224 Gbit/s Mixed Line Rate 15-Channel DP-QPSK and DP-16QAM Contiguous Spectrum Based Networks

    DEFF Research Database (Denmark)

    Asif, Rameez

    2014-01-01

    We evaluated that in-line non-linear compensation schemes decrease the com- plexity of digital back-propagation and enhance the perfor mance of 40/112/224Gbit/s mixed line rate network. Both grouped and un-grouped spectral all ocation schemes are investigated....

  12. Corrective Action Decision Document for Corrective Action Unit 224: Decon Pad and Septic Systems Nevada Test Site, Nevada, Rev. No.: 0

    Energy Technology Data Exchange (ETDEWEB)

    David A. Strand

    2005-05-01

    This Corrective Action Decision Document has been prepared for Corrective Action Unit (CAU) 224, Decon Pad and Septic Systems, in Areas 2, 3, 5, 6, 11, and 23 of the Nevada Test Site, Nevada, in accordance with the ''Federal Facility Agreement and Consent Order'' (1996). Corrective Action Unit 224 is comprised of the following corrective action sites (CASs): (1) 02-04-01, Septic Tank (Buried); (2) 03-05-01, Leachfield; (3) 05-04-01, Septic Tanks (4)/Discharge Area; (4) 06-03-01, Sewage Lagoons (3); (5) 06-05-01, Leachfield; (6) 06-17-04, Decon Pad and Wastewater Catch; (7) 06-23-01, Decon Pad Discharge Piping; (8) 11-04-01, Sewage Lagoon; and (9) 23-05-02, Leachfield. The purpose of this Corrective Action Decision Document is to identify and provide the rationale for the recommendation of a corrective action alternative for the nine CASs within CAU 224. Corrective action investigation activities were performed from August 10, 2004, through January 18, 2005, as set forth in the CAU 224 Corrective Action Investigation Plan.

  13. Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation.

    Directory of Open Access Journals (Sweden)

    Clint L Miller

    2014-03-01

    Full Text Available Genome-wide association studies (GWAS have identified chromosomal loci that affect risk of coronary heart disease (CHD independent of classical risk factors. One such association signal has been identified at 6q23.2 in both Caucasians and East Asians. The lead CHD-associated polymorphism in this region, rs12190287, resides in the 3' untranslated region (3'-UTR of TCF21, a basic-helix-loop-helix transcription factor, and is predicted to alter the seed binding sequence for miR-224. Allelic imbalance studies in circulating leukocytes and human coronary artery smooth muscle cells (HCASMC showed significant imbalance of the TCF21 transcript that correlated with genotype at rs12190287, consistent with this variant contributing to allele-specific expression differences. 3' UTR reporter gene transfection studies in HCASMC showed that the disease-associated C allele has reduced expression compared to the protective G allele. Kinetic analyses in vitro revealed faster RNA-RNA complex formation and greater binding of miR-224 with the TCF21 C allelic transcript. In addition, in vitro probing with Pb2+ and RNase T1 revealed structural differences between the TCF21 variants in proximity of the rs12190287 variant, which are predicted to provide greater access to the C allele for miR-224 binding. miR-224 and TCF21 expression levels were anti-correlated in HCASMC, and miR-224 modulates the transcriptional response of TCF21 to transforming growth factor-β (TGF-β and platelet derived growth factor (PDGF signaling in an allele-specific manner. Lastly, miR-224 and TCF21 were localized in human coronary artery lesions and anti-correlated during atherosclerosis. Together, these data suggest that miR-224 interaction with the TCF21 transcript contributes to allelic imbalance of this gene, thus partly explaining the genetic risk for coronary heart disease associated at 6q23.2. These studies implicating rs12190287 in the miRNA-dependent regulation of TCF21, in

  14. 不同胎龄及出生体质量双胎早产儿224例临床分析%Clinical Analysis of 224 Twin Premature Infants with Different Gestational Age and Birth Weight

    Institute of Scientific and Technical Information of China (English)

    廖镇宇; 黄瑞文; 肖艾青

    2014-01-01

    【目的】分析不同胎龄及出生体质量双胎早产儿并发症发生率及死亡原因。【方法】将2010年7月至2012年7月在本院新生儿科住院的224例双胎早产儿,根据胎龄分为≤32周,~34周,~37周组,根据出生体质量分为<1500 g,~2500 g,≥2500 g组。比较各组患儿并发症的发生率及病死率。【结果】贫血、呼吸衰竭、早产儿视网膜病变、新生儿呼吸窘迫综合征、支气管肺发育不良在不同胎龄及出生体质量双胎早产儿组间比较差异有统计学意义(P<0.05),且胎龄越小,出生体质量越低,发生率越高;低血糖在不同胎龄及出生体质量双胎早产儿组间比较差异有统计学意义(P<0.05),且出生体质量越低,发生率越高;呼吸暂停在不同胎龄及出生体质量双胎早产儿组间比较差异有统计学意义(P<0.05)。224例患儿中死亡15例,病死率为6.7%。胎龄越小、出生体质量越低,病死率越高,各组间比较差异有统计学意义(P<0.05)。【结论】加强双胎早产儿孕母的保健工作,降低早产儿及低出生体质量儿的发生率;加强双胎早产儿常见并发症的防治,以降低其病死率。%[Obj ective]To analyze the incidence of the complications and mortality rate of twin premature infants with different gestational age and birth weight.[Methods]According to gestational age,224 twin premature infants hos-pitalized in neonate department of our hospital from July 2010 to July 2012 were divided into less than 32-week group,32~34-week group and 34~37 week group.According to birth weight,all patients were divided into less than 1500g group,1500-2500g group and more than 2500g group.The incidence of complications and mortality rate were compared among different groups.[Results]There were significant differences in the incidence of anemia,respiratory failure,reti-nopathy of prematurity

  15. Sediment-water column fluxes of carbon, oxygen and nutrients in Bedford Basin, Nova Scotia, inferred from 224Ra measurements

    Directory of Open Access Journals (Sweden)

    E. Horne

    2012-07-01

    Full Text Available Exchanges between sediment pore waters and the overlying water column play a significant role in the chemical budgets of many important chemical constituents. Quantification of such benthic fluxes requires explicit knowledge of the sediment properties and biogeochemistry. Alternatively, changes in water column properties near the sediment-water column interface can be exploited to gain insight into the sediment biogeochemistry and benthic fluxes. Here, we apply a 1-D diffusive mixing model to near-bottom water column profiles of 224Ra activity in order to yield vertical eddy diffusivities (KZ, based upon which we assess the diffusive exchange of inorganic carbon (DIC, nutrients and oxygen (O2, across the sediment-water interface in a coastal inlet, Bedford Basin, Nova Scotia, Canada. Near-bottom observations of DIC, O2 and nutrients provide flux ratios similar to Redfield values, suggesting that benthic respiration of primarily marine organic matter is the dominant driver. Furthermore, we did not observe any significant release of alkalinity (AT from the sediments to the overlying water column, providing further insight into the dominant reactions taking place within sediments: the respiration of organic matter occurs largely under aerobic conditions or products of anaerobic processes are reoxidized quickly in oxygenated layers of the sediments. Finally, comparison with other carbon sources reveal the observed benthic DIC release as a significant contributor to the Bedford Basin carbon system.

  16. Scintigraphic, radiological and clinical results after /sup 224/Ra therapy in patients with Bechterew's disease

    Energy Technology Data Exchange (ETDEWEB)

    Redecker, S.; Crone-Muenzebrock, W.; Weh, L.; Montz, R. (Hamburg Univ. (Germany, F.R.))

    1982-04-01

    53 patients with ancylosing spondylitis (clinical stages II and III) were treated with 1 MBq Ra 224 over a period of ten weeks. In 44 patients the orthopaedic findings were improved, in 9 patients they remained unchanged. An iridocyclitis developed in 3 patients, in 1 case an uveitis could be observed 33 patients were reexamined clinically, radiologically including total body scan and by laboratory means after an average period of 7.1 years. The stiftness of the spine was slightly improved compared with the pre-therapeutical status. Radiologically the spine findings were unchanged in 7 patients, progradient in 16, and clearly deteriorated in 8 cases. Scintiscanning of the skeleton of 21 patients showed a normal activity in 6 patients, 8 patients had a slight increase of the activity, mainly in the sacroiliac region 7 patients revealed a highly increased activity in the sacro-iliac region and lumbovertebral spine. Differential blood count and electrophoresis were unchanged before and after therapy. In 60% of the cases the erythrocyte sedimentation rate was diminished compared with pretherapy findings, in 40% the rate was unchanged or increased. Subjectively 10% of the patients reported no pain symptoms, 50% felt better, 30% were unchanged and 10% felt more poorly than before.

  17. Dimer of Bis[trans-5-methyl-2-[2-(4-methoxylphenyl) ethenyl]-benzoxazole]di-μ-nitratosilver(I)

    Institute of Scientific and Technical Information of China (English)

    LIU Hui-Min; ZHANG Wei; XIN Ying; ZHANG Wen-Qin

    2004-01-01

    The title complex [AgNO3(C17H15NO2)2]2 was synthesized and characterized by X-ray diffraction analysis. The compound crystallizes in triclinic, space group Pī with a = 11.226(7), b = 11.906(7), c = 12.144(7) (A。), α = 99.796(10), β = 91.631(10), γ = 101.225(10)°, V = 1565.6(16)(A。)3, Z = 1, Mr = 1400.96, Dc = 1.486 g/cm3, F(000) = 716 and μ(Mo-Kα) = 0.697 mm-1. The final R and wR are 0.0401 and 0.0995, respectively for 5492 independent observable reflections with I > 2σ(I). The results show that the central Ag atom is four-coordinated with two O atoms from two distinct NO3- anions and two N atoms from two trans-5-methyl-2-[2-(4-methoxylphenyl)ethenyl]- benzoxazole ligands, and the two Ag atoms bridged with two O atoms give an interesting Ag-O-Ag-O parallelogram structure. The coordination sphere of Ag atom exhibits a heavily distorted tetrahedral geometry and the coordination angles lie in the range of 66.73(12)~129.59(10)°. The intra- molecular dihedral angles between the benzoxazolyl and phenyl planes are 4.1(3) and 2.9(3)°, respectively.

  18. 湖南省106 224例新生儿先天性甲状腺功能减低症筛查%Screening for congenital hypothyroidism in 106 224 neonates in Hunan Province

    Institute of Scientific and Technical Information of China (English)

    伍细言; 王华; 黄定梅; 雷花香; 胡蓉; 马力; 邹珊静; 禹虹

    2005-01-01

    目的:早期诊断先天性甲状腺功能减退症(congenital hypothyroidism,CH)患儿,预防智力低下儿的发生.方法:采用时间分辨荧光免疫法测定促甲状腺素(thyroid-stimulating hormone,TSH)浓度,如果TSH筛查呈阳性,则使用化学发光免疫法(chemiluminescent immunoassay,CLIA)测定血清TSH、游离三碘甲状腺原氨酸(free triiodothyronine,FT3)、游离四碘甲状腺原氨酸(free thyroxin,FT4),并结合临床确诊.结果:湖南省1997年4月至2003年12月106 224份标本中共检出CH患儿68例,检出率1/1 562,明显高于全国平均水平(1/3 009).结论:(1)新生儿筛查是早期诊治CH患儿,预防CH发生智力低下的关键;(2)湖南为CH高发地区;(3)检出率与科学技术的发展呈相关性,累加检出率能更真实地反映发病率;(4)选择适当切值有助于防止漏筛.

  19. 爱特梅尔maXTouch mXT224E助力三星Galaxy S II智能手机触摸屏

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    微控制器及触摸解决方案的领导厂商爱特梅尔公司(Atmel)宣布三星公司(Samsung)已经选择爱特梅尔maXTouch mXT224E控制器来助力其新一代Galaxy SII触摸屏。mXT224E是全新maXTouch E-系列中的一员.具有先进的噪声抑制功能.可以实现更薄的触摸屏配置.如”外挂式”(on-celf,触摸传感器图形设置于显示面板上)配置设计。

  20. Expression of antisense miR-224 in colon cancer and its effect on cancer cell proliferation%反义 miR-224在结肠癌组织中的表达及其对癌细胞增殖的影响

    Institute of Scientific and Technical Information of China (English)

    胡刚; 湛汇

    2015-01-01

    目的探讨微小 RNA(miRNA)miR-224在结肠癌组织中的表达,以及对体外癌细胞增殖和凋亡的影响。方法收集2011年2月至2014年3月行手术治疗的134例结肠癌和癌旁组织标本,利用实时荧光定量聚合酶链反应(Real-time PCR)检测标本中 miR-224表达情况;对人结肠癌细胞 SW480进行 miR-224反义寡核苷酸转染并培养,利用克隆形成实验和流式细胞仪检测 miR-224反义寡核苷酸对 SW480细胞增殖和凋亡的影响,利用 Real-time PCR 和 Western blot 法对不同转染组细胞中 Bcl-2表达情况进行检测。结果miR-224在结肠癌组织中相对表达水平显著高于癌旁组织(P <0.05);反义 miR-224组人结肠癌 SW480细胞克隆形成率显著低于对照组,而细胞凋亡指数则高于对照组,差异均具有统计学意义(P <0.05);反义 miR-224组细胞 Bcl-2相对表达量和蛋白相对表达量均低于对照组(P <0.05)。结论miR-224在结肠癌组织中呈高表达,减少 miR-224表达可抑制结肠癌细胞增殖,并加速细胞凋亡,有可能成为结肠癌早期发现及基因治疗的新靶位。%Objective To explore the expression of miR-224 in colon cancer and examine its effect on the proliferation and apoptosis of cancer cell.Methods A total of 134 cases of colon cancer and adjacent tissue specimens were collected from Feb.201 1 to Mar.2014.And the expression of miR-224 was detected by real-time polymerase chain reaction (PCR).Human colon cancer cell SW480 was transfected by miR-224 antisense oligonucleotide and cultured.The effects of miR-224 antisense oligonucleotide on cellular proliferation and apoptosis were detected by colony formation assay and flow cytometry.And the expressions of Bcl-2 in differentially transfected cells were detected by real-time PCR and Western blot.Results The relative expression of miR-224 was significantly higher in colon cancer tissue than that in adjacent tissues.And the difference was

  1. Antibacterial activity of cyclo(L-Pro-L-Tyr) and cyclo(D-Pro-L-Tyr) from Streptomyces sp. strain 22-4 against phytopathogenic bacteria.

    Science.gov (United States)

    Wattana-Amorn, Pakorn; Charoenwongsa, Waranya; Williams, Christopher; Crump, Matthew P; Apichaisataienchote, Busaya

    2016-09-01

    Two bioactive cyclic dipeptides, cyclo(L-Pro-L-Tyr) and cyclo(D-Pro-L-Tyr), were isolated from the culture broth of Streptomyces sp. strain 22-4 and tested against three economically important plant pathogens, Xanthomonas axonopodis pv. citri, Ralstonia solanacearum and Clavibacter michiganensis. Both cyclic dipeptides were active against X. axonopodis pv. citri and R. Solanacearum with MIC of 31.25 μg/mL. No activity could be observed against C. michiganensis.

  2. Comment: 224 [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available ty of Tokyo) licensed under CC Attribution2.1 Japan ヨコヅナクマムシ 光学顕微鏡写真 撮影:國枝武和(東京大学) bando 2010/02/15 14:55:40 2010/02/16 10:42:46 ...

  3. Densities, viscosities, refractive indices, and surface tensions for binary and ternary mixtures of 2-propanol, tetrahydropyran, and 2,2,4-trimethylpentane

    Energy Technology Data Exchange (ETDEWEB)

    Kao, Y.-C. [Department of Applied Chemistry, Providence University, Shalu 43301, Taiwan (China); Tu, C.-H., E-mail: chtu@pu.edu.t [Department of Applied Chemistry, Providence University, Shalu 43301, Taiwan (China)

    2011-02-15

    Densities, viscosities, refractive indices, and surface tensions of the ternary system (2-propanol + tetrahydropyran + 2,2,4-trimethylpentane) at T = 303.15 K and its constituent binary systems (2-propanol + tetrahydropyran, 2-propanol + 2,2,4-trimethylpentane, and tetrahydropyran + 2,2,4-trimethylpentane) at T = (293.15, 303.15, 313.15, and 323.15) K were measured at atmospheric pressure. Densities were determined using a vibrating-tube densimeter. Viscosities were measured with an automatic microviscometer based on the rolling-ball principle. Refractive indexes were measured using a digital Abbe-type refractometer. Surface tensions were determined by the Wilhelmy-plate method. From these data, excess molar volumes, deviations in viscosity, deviations in refractive index, and deviations in surface tension were calculated. The results for the binary and ternary systems were fitted to the Redlich-Kister equation and the variable-degree polynomials in terms of compositions, respectively. The experimental and calculated quantities are used to study the nature of mixing behaviour between mixture components.

  4. Verification of anticlockwise gyre in the semi-closed water area of Lake Nakaumi, southwest Japan, by using 224Ra/228Ra activity ratios

    International Nuclear Information System (INIS)

    The Honjyo area in Lake Nakaumi is a semi-closed brackish water area where some mixing of up-flowing marine water and down-flowing lake water take place. A large-scale gyre that caused by the residual circulation was once indicated by a temporal algal blooming that spread over the semi-closed Honjyo area in brackish Lake Nakaumi. In order to verify this type of water circulation, we examined 224Ra (t1/2=3.66 d)/228Ra (t1/2=5.75 y) activity ratios of both upper and lower waters that differentiated by a well-developed halocline. The 224Ra/228Ra ratios in the upper water were lowest in the central area, suggesting the formation of anticlockwise gyre. The ratios in the lower water were rather uniform, but a basin-wide anticlockwise flow of water is also indicated. The 224Ra/228Ra ratio is clearly effective to trace the water flow for both the deep and surface waters. (author)

  5. Distribution of (223)Ra and (224)Ra in the Bo Sea embayment in Tianjin and its implication of submarine groundwater discharge.

    Science.gov (United States)

    Liu, Lingling; Yi, Lixin; Cheng, Xiaoqing; Tang, Guoqiang

    2015-12-01

    Submarine groundwater discharge (SGD) is now recognized as an important pathway between land and sea. In this study, in order to analyze the distribution of naturally occurring short-lived radium isotopes and the relative SGD effect in Bo Sea embayment, (223)Ra and (224)Ra were measured in three parts of the embayment with the radium-delayed coincidence counting (RaDeCC) system. Subsequently, the mixing process was studied by the calculation of diffusion coefficients (Kx and Kz) and advection velocities (Vx and Vz) based on the 2D advection-diffusion model. Additionally, the apparent residence ages and SGD flux were quantified based on the (224)Ra and (223)Ra activities. The results showed that the Ra activities exponentially decreased with the distance offshore, and both the Kx and Vx took the order of northern part > southern part > middle part. In vertical direction, there was the maximum value of Vz and minimum Kz in middle part and the maximum Kz and minimum Vz in southern part. The average ages for the northern, middle and southern parts were 4.28, 7.38 and 3.73 days, respectively. The final SGD flux yielded by (224)Ra was 0.09, 0.01 and 0.03 m d(-1) in the northern, middle and southern parts, respectively. The SGD flux yielded by (223)Ra was 0.08, 0.01 and 0.03 m d(-1) in northern, middle and southern parts, respectively. The result indicates that there is the fastest exchange rate and the biggest SGD flux in the southern part in Bo Sea embayment. PMID:26318773

  6. The Equilibrium and Pre-Equilibrium Neutron Emission Spectra of Some Deformed Target Nuclei for (p,xn) Reactions up to 22.4 MeV

    International Nuclear Information System (INIS)

    In this study, by using equilibrium and pre-equilibrium reaction mechanisms, neutron-emission spectra produced by (p,xn) reactions for some deformed target nuclei as 165Ho, 181Ta and 232Th have been calculated the bombarding energies up to 22.4 MeV. In the calculations, pre-equilibrium calculations were calculated by using new evaluated hybrid model and geometry dependent hybrid model, full exciton model and cascade exciton model. The reaction equilibrium component was calculated by Weisskopf-Ewing model. The obtained results have been discussed and compared with the available experimental data and found agreement with each other

  7. RRS Discovery Cruise 224 Leg 2, 30 Dec-17 Jan 1997. Biological and physical investigations in the region of the Almeira-Oran Front (western Mediterranean)

    OpenAIRE

    Pugh, P.R.

    1997-01-01

    The purpose of Discovery Cruise 224, Leg 2, was to continue the physical and biological surveys previously undertaken during Leg 1 as part of the EEC MAST OMEGA Project; and to undertake comparisons of the western Mediterranean macrozooplankton and micronekton communities on either side of the Almeria-Oran Front. The sampling programme consisted of: 1) Fine scale SeaSoar surveys, at the beginning and end of the leg, to investigate the changes in the structure of the Almeria-Oran frontal s...

  8. Directed and elliptic flow of charged particles in Cu+Cu collisions at $\\sqrt{\\bm {s_{NN}}} =$ 22.4 GeV

    CERN Document Server

    Agakishiev, G; Ahammed, Z; Alakhverdyants, A V; Alekseev, I; Alford, J; Anderson, B D; Anson, C D; Arkhipkin, D; Averichev, G S; Balewski, J; Beavis, D R; Behera, N K; Bellwied, R; Betancourt, M J; Betts, R R; Bhasin, A; Bhati, A K; Bichsel, H; Bielcik, J; Bielcikova, J; Bland, L C; Bordyuzhin, I G; Borowski, W; Bouchet, J; Braidot, E; Brandin, A V; Bridgeman, A; Brovko, S G; Bruna, E; Bueltmann, S; Bunzarov, I; Burton, T P; Cai, X Z; Caines, H; Sánchez, M Calderón de la Barca; Cebra, D; Cendejas, R; Cervantes, M C; Chaloupka, P; Chattopadhyay, S; Chen, H F; Chen, J H; Chen, J Y; Chen, L; Cheng, J; Cherney, M; Chikanian, A; Choi, K E; Christie, W; Chung, P; Codrington, M J M; Corliss, R; Cramer, J G; Crawford, H J; Cui,; Leyva, A Davila; De Silva, L C; Debbe, R R; Dedovich, T G; Deng, J; Derevschikov, A A; de Souza, R Derradi; Didenko, L; Djawotho, P; Dogra, S M; Dong, X; Drachenberg, J L; Draper, J E; Du, C M; Dunlop, J C; Efimov, L G; Elnimr, M; Engelage, J; Eppley, G; Estienne, M; Eun, L; Evdokimov, O; Fatemi, R; Fedorisin, J; Fersch, R G; Filip, P; Finch, E; Fine, V; Fisyak, Y; Gagliardi, C A; Gangadharan, D R; Geurts, F; Ghosh, P; Gorbunov, Y N; Gordon, A; Grebenyuk, O G; Grosnick, D; Gupta, A; Gupta, S; Guryn, W; Haag, B; Hajkova, O; Hamed, A; Han, L-X; Harris, J W; Hays-Wehle, J P; Heinz, M; Heppelmann, S; Hirsch, A; Hjort, E; Hoffmann, G W; Hofman, D J; Huang, B; Huang, H Z; Humanic, T J; Huo, L; Igo, G; Jacobs, P; Jacobs, W W; Jena, C; Jin, F; Joseph, J; Judd, E G; Kabana, S; Kang, K; Kapitan, J; Kauder, K; Ke, H W; Keane, D; Kechechyan, A; Kettler, D; Kikola, D P; Kiryluk, J; Kisiel, A; Kizka, V; Klein, S R; Knospe, A G; Koetke, D D; Kollegger, T; Konzer, J; Koralt, I; Koroleva, L; Korsch, W; Kotchenda, L; Kouchpil, V; Kravtsov, P; Krueger, K; Krus, M; Kumar, L; Lamont, M A C; Landgraf, J M; LaPointe, S; Lauret, J; Lebedev, A; Lednicky, R; Lee, J H; Leight, W; LeVine, M J; Li, C; Li, L; Li, N; Li, W; Li, X; Li, X; Li, Y; Li, Z M; Lima, 1 L M; Lisa, M A; Liu, F; Liu, H; Liu, J; Ljubicic, T; Llope, W J; Longacre, R S; Lu, Y; Lukashov, E V; Luo, X; Ma, G L; Ma, Y G; Mahapatra, D P; Majka, R; Mall, O I; Manweiler, R; Margetis, S; Markert, C; Masui, H; Matis, H S; McDonald, D; McShane, T S; Meschanin, A; Milner, R; Minaev, N G; Mioduszewski, S; Mitrovski, M K; Mohammed, Y; Mohanty, B; Mondal, M M; Morozov, B; Morozov, D A; Munhoz, M G; Mustafa, M K; Naglis, M; Nandi, B K; Nayak, T K; Nogach, L V; Nurushev, S B; Odyniec, G; Ogawa, A; Oh, K; Ohlson, A; Okorokov, V; Oldag, E W; Oliveira, R A N; Olson, D; Pachr, M; Page, B S; Pal, S K; Pandit, Y; Panebratsev, Y; Pawlak, T; Pei, H; Peitzmann, T; Perkins, C; Peryt, W; Pile, P; Planinic, M; Ploskon, M A; Pluta, J; Plyku, D; Poljak, N; Porter, J; Poskanzer, A M; Potukuchi, B V K S; Powell, C B; Prindle, D; Pruneau, C; Pruthi, N K; Pujahari, P R; Putschke, J; Qiu, H; Raniwala, R; Raniwala, S; Ray, R L; Redwine, R; Reed, R; Ritter, H G; Roberts, J B; Rogachevskiy, O V; Romero, J L; Ruan, L; Rusnak, J; Sahoo, N R; Sakrejda, I; Salur, S; Sandweiss, J; Sangaline, E; Sarkar, A; Schambach, J; Scharenberg, R P; Schaub, J; Schmah, A M; Schmitz, N; Schuster, T R; Seele, J; Seger, J; Selyuzhenkov, I; Seyboth, P; Shah, N; Shahaliev, E; Shao, M; Sharma, M; Shi, S S; Shou, Q Y; Sichtermann, E P; Simon, F; Singaraju, R N; Skoby, M J; Smirnov, N; Solanki, D; Sorensen, P; deSouza, U G; Spinka, H M; Srivastava, B; Stanislaus, T D S; Steadman, S G; Stevens, J R; Stock, R; Strikhanov, M; Stringfellow, B; Suaide, A A P; Suarez, M C; Subba, N L; Sumbera, M; Sun, X M; Sun, Y; Sun, Z; Surrow, B; Svirida, D N; Symons, T J M; de Toledo, A Szanto; Takahashi, J; Tang, A H; Tang, Z; Tarini, L H; Tarnowsky, T; Thein, D; Thomas, J H; Tian, J; Timmins, A R; Tlusty, D; Tokarev, M; Trentalange, S; Tribble, R E; Tribedy, P; Trzeciak, B A; Tsai, O D; Ullrich, T; Underwood, D G; Van Buren, G; van Nieuwenhuizen, G; Vanfossen, J A; Jr.,; Varma, R; Vasconcelos, G M S; Vasiliev, A N; Videbæk, F; Viyogi, Y P; Vokal, S; Voloshin, S A; Wada, M; Walker, M; Wang, F; Wang, G; Wang, H; Wang, J S; Wang, Q; Wang, X L; Wang, Y; Webb, G; Webb, J C; Westfall, G D; Whitten, C; Wieman, H; Wissink, S W; Witt, R; Witzke, W; Wu, Y F; Xiao, Z; Xie, W; Xu, H; Xu, N; Xu, Q H; Xu, W; Xu, Y; Xu, Z; Xue, L; Yang, Y; Yang, Y; Yepes, P; Yip, K; Yoo, I-K; Zawisza, M; Zbroszczyk, H; Zhan, W; Zhang, J B; Zhang, S; Zhang, W M; Zhang, X P; Zhang, Y; Zhang, Z P; Zhao, F; Zhao, J; Zhong, C; Zhu, X; Zhu, Y H; Zoulkarneeva, Y

    2011-01-01

    This paper reports results for directed flow $v_{1}$ and elliptic flow $v_{2}$ of charged particles in Cu+Cu collisions at $\\sqrt{s_{NN}}=$ 22.4 GeV at the Relativistic Heavy Ion Collider. The measurements are for the 0-60% most central collisions, using charged particles observed in the STAR detector. Our measurements extend to 22.4 GeV Cu+Cu collisions the prior observation that $v_1$ is independent of the system size at 62.4 and 200 GeV, and also extend the scaling of $v_1$ with $\\eta/y_{\\rm beam}$ to this system. The measured $v_2(p_T)$ in Cu+Cu collisions is similar for $\\sqrt{s_{NN}} = 22.4-200$ GeV. We also report a comparison with results from transport model (UrQMD and AMPT) calculations. The model results do not agree quantitatively with the measured $v_1(\\eta), v_2(p_T)$ and $v_2(\\eta)$.

  9. Optical variability of the BL Lacertae object GC 0109+224. Multiband behaviour and time scales from a 7-years monitoring campaign

    CERN Document Server

    Ciprini, S; Raiteri, C M; Villata, M; Ibrahimov, M A; Nucciarelli, G; Lanteri, L

    2003-01-01

    We present the most continuous data base of optical $BVR_{c}I_{c}$ observations ever published on the BL Lacertae object GC 0109+224, collected mainly by the robotic telescope of the Perugia University Observatory in the period November 1994-February 2002. These observations have been complemented by data from the Torino Observatory, collected in the period July 1995-January 1999, and Mt. Maidanak Observatory (December 2000). GC 0109+224 showed rapid optical variations and six major outbursts were observed at the beginning and end of 1996, in fall 1998, at the beginning and at the end of 2000, and at the beginning of 2002. Fast and large-amplitude drops characterized its flux behaviour. The $R_c$ magnitude ranged from 13.3 (16.16 mJy) to 16.46 (0.8 mJy), with a mean value of 14.9 (3.38 mJy). In the periods where we collected multi-filter observations, we analyzed colour and spectral indexes, and the variability patterns during some flares. The long-term behaviour seems approximatively achromatic, but during s...

  10. High sensitivity measurement of 224Ra and 226Ra in water with an improved hydrous titanium oxide technique at the Sudbury Neutrino Observatory

    CERN Document Server

    Aharmim, B; Dai, X; Doucas, G; Farine, J; Fergani, H; Ford, R; Hahn, R L; Hallman, E D; Jelley, N A; Lange, R; Majerus, S; Mifflin, C; Noble, A J; O'Keeffe, H M; Rodriguez-Jimenez, R; Sinclair, D; Yeh, M

    2008-01-01

    The existing hydrous titanium oxide (HTiO) technique for the measurement of 224Ra and 226Ra in the water at the Sudbury Neutrino Observatory (SNO) has been changed to make it faster and less sensitive to trace impurities in the HTiO eluate. Using HTiO-loaded filters followed by cation exchange adsorption and HTiO co-precipitation, Ra isotopes from 200-450 tonnes of heavy water can be extracted and concentrated into a single sample of a few millilitres with a total chemical efficiency of 50%. Combined with beta-alpha coincidence counting, this method is capable of measuring 2.0x10^3 uBq/kg of 224Ra and 3.7x10^3 uBq/kg of 226Ra from the 232Th and 238U decay chains, respectively, for a 275 tonne D2O assay, which are equivalent to 5x10^16 g Th/g and 3x10^16 g U/g in heavy water.

  11. Prostate cancer stem cell-targeted efficacy of a new-generation taxoid, SBT-1214 and novel polyenolic zinc-binding curcuminoid, CMC2.24.

    Directory of Open Access Journals (Sweden)

    Galina I Botchkina

    Full Text Available BACKGROUND: Prostate cancer is the second leading cause of cancer death among men. Multiple evidence suggests that a population of tumor-initiating, or cancer stem cells (CSCs is responsible for cancer development and exceptional drug resistance, representing a highly important therapeutic target. The present study evaluated CSC-specific alterations induced by new-generation taxoid SBT-1214 and a novel polyenolic zinc-binding curcuminoid, CMC2.24, in prostate CSCs. PRINCIPAL FINDINGS: The CD133(high/CD44(high phenotype was isolated from spontaneously immortalized patient-derived PPT2 cells and highly metastatic PC3MM2 cells. Weekly treatment of the NOD/SCID mice bearing PPT2- and PC3MM3-induced tumors with the SBT-1214 led to dramatic suppression of tumor growth. Four of six PPT2 and 3 of 6 PC3MM2 tumors have shown the absence of viable cells in residual tumors. In vitro, SBT-1214 (100 nM-1 µM; for 72 hr induced about 60% cell death in CD133(high/CD44(+/high cells cultured on collagen I in stem cell medium (in contrast, the same doses of paclitaxel increased proliferation of these cells. The cytotoxic effects were increased when SBT-1214 was combined with the CMC2.24. A stem cell-specific PCR array assay revealed that this drug combination mediated massive inhibition of multiple constitutively up-regulated stem cell-related genes, including key pluripotency transcription factors. Importantly, this drug combination induced expression of p21 and p53, which were absent in CD133(high/CD44(high cells. Viable cells that survived this treatment regimen were no longer able to induce secondary spheroids, exhibited significant morphological abnormalities and died in 2-5 days. CONCLUSIONS: We report here that the SBT-1214 alone, or in combination with CMC2.24, possesses significant activity against prostate CD133(high/CD44(+/high tumor-initiating cells. This drug combination efficiently inhibits expression of the majority of stem cell-related genes and

  12. The Formation of 2,2,4-Trimethyl-2,3-dihydro-1H-1,5-Benzodiazepine from 1,2-Diaminobenzene in the Presence of Acetone

    Directory of Open Access Journals (Sweden)

    Felix Odame

    2013-11-01

    Full Text Available In an attempt to synthesize a 2-substituted benzimidazole from the reaction of o-phenylenediamine and isophthalic acid in the presence of acetone and ethanol under microwave irradiation, a salt of the isophthalate ion and 2,2,4-trimethyl-2,3-dihydro-1H-1,5-benzodiazepin-5-ium ion was obtained. The condensation of two moles of acetone with the amine groups resulted in the formation of the benzodiazepine which crystallized as an iminium cation forming a salt with the isophthalate anion. The formation of benzodiazepine was also confirmed by performing the reaction of o-phenylenediamine with excess acetone in ethanol under conventional heating conditions. The compounds were characterized by NMR, FTIR, HRMS and microanalysis as well as X-ray crystallography. The reaction mechanism leading to the formation of benzodiazepine is also discussed.

  13. Mass spectral characteristics of the chlorinated disinfection byproduct 2,2,4-trichloro-5-methoxy-cyclopent-4-ene-1,3-dione

    Science.gov (United States)

    Gong, Huijuan; Bao, Yanchu; Yang, Jihong; Jiang, Qin; Chen, Zezhi

    2010-06-01

    The objective of this paper was to correct the mistakes of a previous interpretation of electron impact ionization (EI) mass spectrum of the chlorinated disinfection byproduct (DBP) in drinking water naming 2,2,4-trichloro-5-methoxy-cyclopent-4-ene-1,3-dione (TCMCD). Moreover the positive-ion chemical ionization (CI +) and electrospray ionization (ESI +) mass spectra were also studied. As the search of new chlorinated disinfection byproducts in drinking water is a challenge and researchers generally have to attempt to identify unknown chlorinated products generated from incompletely defined starting materials, fully understanding the mass spectra of this compound may do some help for the analysis of other unknown chlorinated disinfection byproducts.

  14. Corrective Action Investigation Plan for Corrective Action Unit 224: Decon Pad and Septic Systems Nevada Test Site, Nevada, Rev. No.: 0, with ROTC 1 and 2

    Energy Technology Data Exchange (ETDEWEB)

    David A. Strand

    2004-04-01

    This Corrective Action Investigation Plan (CAIP) contains project-specific information including facility descriptions, environmental sample collection objectives, and criteria for conducting site investigation activities at Corrective Action Unit (CAU) 224: Decon Pad and Septic Systems, Nevada Test Site (NTS), Nevada. This CAIP has been developed in accordance with the ''Federal Facility Agreement and Consent Order'' (FFACO) (1996) that was agreed to by the State of Nevada, the U.S. Department of Energy (DOE), and the U.S. Department of Defense (DoD). The NTS is approximately 65 miles (mi) northwest of Las Vegas, Nevada (Figure 1-1). Corrective Action Unit 224 is comprised of the nine Corrective Action Sites (CASs) listed below: 02-04-01, Septic Tank (Buried); 03-05-01, Leachfield; 05-04-01, Septic Tanks (4)/Discharge Area; 06-03-01, Sewage Lagoons (3); 06-05-01, Leachfield; 06-17-04, Decon Pad and Wastewater Catch; 06-23-01, Decon Pad Discharge Piping; 11-04-01, Sewage Lagoon; and 23-05-02, Leachfield. Corrective Action Sites 06-05-01, 06-23-01, and 23-05-02 were identified in the 1991 Reynolds Electrical & Engineering Co., Inc. (REECo) inventory (1991). The remaining sites were identified during review of various historical documents. Additional information will be obtained by conducting a corrective action investigation (CAI) prior to evaluating and selecting a corrective action alternative for each CAS. The CAI will include field inspections, radiological and geological surveys, and sample collection. Data will also be obtained to support investigation-derived waste (IDW) disposal and potential future waste management decisions.

  15. A review of oceanographic and meteorological controls on the North Sea circulation and hydrodynamics with a view to the fate of North Sea methane from well site 22/4b and other seabed sources

    NARCIS (Netherlands)

    Nauw, J.; de Haas, H.; Rehder, G.

    2015-01-01

    The North Sea hydrodynamics are key to the redistribution of methane released at the 22/4b Site, locatedat (57?550N, 1?380E) in the UK Central North Sea, 200 km east of the Scottish mainland. This reviewsummarizes the current state of knowledge on the North Sea circulation, stratification, and varia

  16. 228Ra, 226Ra, 224Ra and 223Ra in potential sources and sinks of land-derived material in the German Bight of the North Sea: implications for the use of radium as a tracer

    NARCIS (Netherlands)

    Schmidt, C.; Hanfland, C.; Regnier, P.; Van Cappellen, P.; Schlüter, M.; Knauthe, U.; Stimac, I.; Geibert, W.

    2011-01-01

    Activities of the naturally occurring radium nuclides 228Ra, 226Ra, 224Ra and 223Ra were determined in waters of the open German Bight and adjacent nearshore areas in the North Sea, in order to explore the potential use of radium isotopes as natural tracers of land–ocean interaction in an environmen

  17. 球形节杆菌C224分批发酵2-酮基-D-葡萄糖酸的条件优化及其动力学模型的构建%Optimization of 2-keto-D-gluconic acid batch fermentation by Arthrobacter globiformis C224 and its kinetics

    Institute of Scientific and Technical Information of China (English)

    孙文敬; 高培玲; 魏转; 崔凤杰; 周延政; 滕文华; 刘敬泽

    2013-01-01

    In the present study,the operation parameters including aeration rate and initial glucose concentration during 50-L batch fermentation were optimized to increase the 2-keto-D-gluconic acid (2KGA) productivity from rice starch hydrolysate by Arthrobacter globiformis C224.The kinetic models for describing the cell growth,2KGA production and glucose consumption were proposed by using Logistic/Luedeking-Piret equations and mass balance calculation.Results showed that the 2KGA yield decreased slightly and its productivity lowered significantly when the aeration rate was below 1.5 v · v-1 · m-1 The initial glucose concentrations varying from 120.0 g/L to 180.0 g/L were optimal.Under the optimized conditions,the productivities and yields reached to 6.36 ~6.54 g/(L · h) and 0.96 ~0.97 g/g,respectively.Those proposed models could fit the predictive values well with the obtained experimental data.The determination coefficients (R2) of all models were over 0.95,which also indicated that theses models could elucidate the 2KGA metabolic characteristics of Arthrobacter globiformis C224.%通过优化发酵条件,提高球形节杆菌C224菌株利用大米淀粉水解糖分批发酵2-酮基-D-葡萄糖酸的生产强度,并在此基础上构建其发酵动力学模型.在50 L的发酵罐上考察了通气量与葡萄耱浓度对2-酮基-D-葡萄糖酸发酵的影响,并基于Logistic方程、Luedeking-Piret方程和物料平衡计算分别构建了菌体生长、产物形成和底物消耗的动力学模型.研究结果表明,通气量低于1.5 v·v-1·m-1时,发酵生产强度明显减小,糖酸转化率有所降低;发酵培养基中的葡萄糖浓度以120.0~180.0 g/L为宜,过高或过低对生产强度和糖酸转化率均有不利影响.在适宜的发酵条件下,球形节杆菌C224菌株分批发酵生产2-酮基-D-葡萄糖酸的生产强度达6.36~6.54 g/(L h),糖酸转化率为0.96 ~ 0.97 g/g.所构建动力学模型的计算值与实验值拟合效果

  18. Research on Magnetic Propertied of Ni50.3Mn27.3Ga22.4 Magnetic Shape Memory Alloy Thin Film%Ni50.3Mn27.3Ga22.4磁性形状记忆合金薄膜的磁性能研究

    Institute of Scientific and Technical Information of China (English)

    艾瑞波; 刘超; 孙祺; 牟海维

    2013-01-01

    采用磁控溅射方法制备Ni50.3Mn27.3Ga22.4磁性形状记忆合金薄膜.系统研究薄膜的马氏体相交行为、磁场增强相变应变特性以及温度对磁感生应变的影响.试验结果表明,经823 K退火1h的Ni50.3Mn27.3Ga22.4薄膜室温下处于奥氏体态,马氏体相变开始温度为271.5 K.当沿膜面方向施加0-0.8 T磁场时,Ni50.3Mn27.3Ga22.4薄膜的马氏体相变应变量随磁场强度的增大而增大,呈现出磁场增强马氏体相交应变效应.试验还发现,饱和磁感生应变显著依赖于测试温度.当测试温度低于拟马氏体相变结束温度时,饱和磁感生应变随温度的升高先缓慢增大,在马氏体相变开始温度附近磁感生应变值发生跳跃式增加,然后随测试温度的进一步升高而降低.%The Ni50.3Mn27.3Ga22.4 magnetic shape memory alloy thin film has been prepared by using magnetron sputtering method.The martensitic transformation behavior,magnetic-field enhancement strain and the effect of temperature on magneitc-field-induced strain have been systematically investigated.The results show that the Ni50.3Mn27.3 Ga2z.4 alloy thin film annealed at 823 K for 1 hour is at austenite phase state at room temperature,and the martensitic tansformation starting temperature is approximately 271.5 K.It is found that martensitic transformation strain increases with increasing external magnetic field along with the film plane when the field increases from 0 to 0.8 T,showing magnetic field enhancement effect to martensitic transformation strain.It is also found that the saturated magnetic-field-induced strains (MFIS) of Ni-Mn-Ga thin films remarkably depend on operation temperatures.The saturated MFIS of Ni50.3 Mn27.3Ga22.4 thin films firstly increases and then decreases with increasing operation temperature below reverse martensitic transformation end temperature(Af) and the maximum saturated MFIS can be obtained around the martensitic transformation start temperature (Ms).

  19. 三个新HLA等位基因A*24:224,A*24:225和A*24:257的测序鉴定%Identification of 3 novel HLA-A alleles A * 24: 224, A * 24 : 225 and A * 24: 257 by sequence-based typing

    Institute of Scientific and Technical Information of China (English)

    朱传福; 张红卫; 张毅; 聂向民

    2015-01-01

    目的 鉴定3个在中国汉族人群中发现的人类白细胞抗原(human leukocyte antigen,HLA)A位点新等位基因A* 24:224、A* 24:225和A* 24:257.方法 应用双链直接测序分型技术进行中华骨髓库志愿者常规HLA分型,对其中HLA-A位点无完全匹配结果者,采用等位基因特异性扩增测序分型方法进行新等位基因序列鉴定.结果 3例先证者在HLA-A位点分别有一个未知的新碱基序列,3个新序列均与HLA-A* 24:02:01:01最为相近,但在第2外显子分别出现了1或2个的碱基取代,并导致相应的密码子及其编码的氨基酸的改变.结论 3个新碱基序列均确认为HLA-A新等位基因,分别于2012年11月和2013年11月被世界卫生组织HLA因子命名委员会正式命名为HLA-A* 24:224、HLA-A*24:225和HLA-A* 24:257.%Objective To verify 3 novel HLA-A alleles A * 24:224,A * 24:225 and A * 24:257 identified in Chinese Han individuals.Methods No full matched results were obtained at HLA-A locus in HLA typing for China Marrow Donor Program (CMDP) using bi-allelic Sequence-Based Typing (SBT).The novel HLA alleles were identified with allele-specific amplification SBT.Results All of the three probands had a novel nucleotide sequence at HLA-A locus.All of the 3 new sequences are most close to HLA-A* 24:02:01:01 except for 1 or 2 nucleotide substitution in exon 2,which resulted in different changes in corresponding codons and encoded amino acids.Conclusion Three novel HLA-A alleles were confirmed and officially named as HLA-A * 24:224,HLA-A * 24:225 and HLA-A * 24:257 under the GenBank accession numbers JQ899198,JQ924283 and HG003642 by the WHO Nomenclature Committee for Factors of the HLA System in November 2012 and November 2013,respectively.

  20. Quaternary (liquid + liquid) equilibria for (methanol + 2,2,4-trimethylpentane + toluene + 1,1-dimethylpropyl methyl ether or 1,1-dimethylethyl methyl ether) at T = 298.15 K

    Energy Technology Data Exchange (ETDEWEB)

    Tamura, Kazuhiro [Department of Chemistry and Chemical Engineering, Division of Material Science, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192 (Japan)]. E-mail: tamura@t.kanazawa-u.ac.jp; Chen, Yao [Department of Chemistry and Chemical Engineering, Division of Material Science, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192 (Japan); Li Hengde [Department of Chemistry and Chemical Engineering, Division of Material Science, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192 (Japan)

    2006-01-15

    The experimental equilibrium tie-lines of two quaternary mixtures for (methanol + 1,1-dimethylpropyl methyl ether + toluene + 2,2,4-trimethylpentane) and (methanol + 1,1-dimethylethyl methyl ether + toluene + 2,2,4-trimethylpentane) were measured at the temperature 298.15 K and ambient pressure. The quaternary experimental results and their constituent ternaries have been satisfactorily predicted using binary parameters alone obtained by an associated-solution model that takes into account association of methanol molecules and solvation between (methanol + polar molecules) with allowance for a non-polar interaction given by an extended form of the UNIQUAC model. The results are further compared with those correlated by modified and extended forms of the UNIQUAC models that include multi-body interaction parameters in addition to binary ones.

  1. Cross-sections of two-prong exclusive reactions in ¯pp Interactions at22.4 GeV/c: Alma Ata-Dubna-Helsinki-Moscow-Prague Collaboration

    Science.gov (United States)

    Batyunya, B. V.; Boguslavsky, I. V.; Bruncko, D.; Gramenitsky, I. M.; Lednický, R.; Medved, K. S.; Vrba, V.; Boos, E. G.; Ermilova, D. I.; Temiraliev, T.; Dementiev, R. K.; Rud, V. I.; Korzhavina, I. A.; Tikhonova, L. A.; Levonian, S. V.; Herynek, I.; Lokajíček, M.; Řídký, J.; Šimák, V.; Valkárová, A.; Kanazirsky, H.; Zlatanov, Z.; Villanen, P.; Walck, E.

    1988-03-01

    The results of the cross-section determination of some two-prong final states with one neutral particle (1 C-fits) in ¯ pp-interactions at 22.4 GeV/ c are presented. These results have been obtained from pictures of the HBC “Ludmila”. The methodical problems of the reaction selection are presented, the fulfilling of CP-invariance channels is demonstrated and the energetic behaviour of their cross-sections is analysed.

  2. Letter Report to Address Comments on the Closure Report for Corrective Action Unit 224: Decon Pad and Septic Systems, Nevada Test Site, Nevada, Revision 0, March 2008

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Restoration

    2008-03-17

    The Closure Report (CR) for Corrective Action Unit (CAU) 224, Decon Pad and Septic Systems, was approved by the Nevada Department of Environmental Protection (NDEP) on November 01, 2007. The approval letter contained the following two comments: Comment 1--For 06-05-01, 06-17-04, 06-23-01 provide evidence that the 6 inch VCP pipe originating from building CP-2 is no longer active and sealed to prevent possible future contamination. Comment 2--For the area that includes 06-03-01, provide evidence that active lines are no longer feeding the North and South lagoons and have been sealed to prevent possible future contamination. To address these comments, closure documentation was reviewed, and site visits were conducted to locate and document the areas of concern. Additional fieldwork was conducted in March 2008 to seal the lines and openings described in the two comments. Photographs were taken of the closed drains and lines to document that the NDEP comments were adequately addressed and potential inadvertent discharge to the environment has been eliminated. Investigation and closure documentation was reviewed to identify the locations of potential drains, lines, and other features that could receive and/or transmit liquid. Based on the investigation findings and subsequent closure activities, no openings, distribution boxes, or other features (excluding known floor drains at CP-2) that could receive liquid were found at the CP-2 location (Figure 1), and potential manholes for the north and south sewage lagoons were identified for Corrective Action Site (CAS) 06-03-01 (Figure 2). The distribution box identified in Figure 1 was not located during the investigation and was assumed to have been previously removed.

  3. Effect of 2-amino-2-[2-(4-octylphenyl) ethyl] propane-1,3-diol hydrochloride (FTY 720) on immune liver injury in mice

    Institute of Scientific and Technical Information of China (English)

    Jing-Hua He; Hui-Na Zhang; Zhi-Bin Lin

    2005-01-01

    AIM: To investigate the protective effect against two immune liver injury models in mice by 2-amino-2-[2-(4-octylphenyl)ethyl] propane-1,3-diol hydrochloride and its possible mechanisms in Con A-induced liver damage.METHODS: Liver tissue or hepatocyte injury was monitored biochemically by measuring alanine aminotransferase (sALT)and aspartate aminotransferase (sAST) activity. Hematoxylin & eosin (HE) staining was used for histopathological examination. To evaluate the role of IFN-γ and IL-4 in the iver injury, serum levels of IFN-γ and IL-4 were determined using commercially available ELISA kit at 12 h after Con A challenge. We also determined FTY 720-induced spleen cell apoptosis by flow cytometry analysis or spleen cell proliferation test.RESULTS: Different doses of FTY 720 treatment dramatically reduced circulating markers of hepatocyte injury in two kinds of immunological liver injury models. FTY 720 dramatically reduced the elevated serum IFN-γ and IL-4 levels after Con A injection. Effect of spleen cell supernatants treated with Con A or FTY 720 on hepatocytes showed that ALT activities in cultured hepatocyte supernatants in Con A treatment group increased markedly and FTY 720 could reduce this elevated ALT activities in FTY 720 treatment group. FTY 720 dose-dependently increased the percentage of apoptotic cells in T cells and inhibited splenocyte proliferation induced by Con A.CONCLUSION: Pretreatment with FTY 720 was shown to produce protective effect on the immune liver injury in mice. The possible mechanism of FTY 720 on Con A-induced liver damage is that it could inhibit lymphocyte proliferation and induce lymphocyte apoptosis, resulting in the reduction of IL-4 or IFN-γ release, and subsequently protecting liver from being damaged by Con A.

  4. Ni50.3Mn27.3Ga22.4磁性形状记忆合金薄膜的磁场增强马氏体相变应变研究%Research on Magnetic Field Enhancement Effect to Martensitic Transformation Strain of Ni50.3Mn27.3Ga22.4 Magnetic Shape Memory Alloy Thin Film

    Institute of Scientific and Technical Information of China (English)

    刘超; 牟海维; 孙祺; 张坤

    2012-01-01

    The Ni50.3Mn27.3 Ga22.4 magnetic shape memory alloy thin film has been prepared by using magnetron sputtering method. The crystallographic structure, magnetization behavior and effect of the external magnetic field on martensitic transformation strain have been systematically investigated. The results show that the Ni50.3Mn27.3Ga22.4 alloy thin film annealed at 823 K for 1 hour is at austenite phase state at room temperature, displaying a strong (101) texture. And the saturated magnetization of the thin film is approximately 40 emμ/g at room temperature. It is also found that martensitic transformation strain of the thin film under the application of the external magnetic field from 0 T and 0. 8 T along film plane increases with increasing magnetic field, showing magnetic field enhancement effect to martensitic transformation strain.%采用磁控溅射方法制备Ni50.3 Mn27.3 Ga22.4磁性形状记忆合金薄膜.研究薄膜的晶体结构、磁化行为以及磁场对马氏体相变应变的影响.试验结果表明,经823 K退火1h的Ni50.3 Mn27.3 Ga22.4薄膜,室温下处于奥氏体态,呈较强的(110)织构特性,且室温饱和磁化强度约为40 emμ/gc试验还发现,当沿膜面方向施加0到0.8T磁场时,Ni50.3 Mn27.3 Ga22.4薄膜的马氏体相变应变量随磁场强度的增大而增大,呈现出磁场增强马氏体相变应变效应.

  5. Production of actinium-225 for alpha particle mediated radioimmunotherapy.

    Science.gov (United States)

    Boll, Rose A; Malkemus, Dairin; Mirzadeh, Saed

    2005-05-01

    The initial clinical trials for treatment of acute myeloid leukemia have demonstrated the effectiveness of the alpha emitter (213)Bi in killing cancer cells. Bismuth-213 is obtained from a radionuclide generator system from decay of 10-days (225)Ac parent. Recent pre-clinical studies have also shown the potential application of both (213)Bi, and the (225)Ac parent radionuclide in a variety of cancer systems and targeted radiotherapy. This paper describes our five years of experience in production of (225)Ac in partial support of the on-going clinical trials. A four-step chemical process, consisting of both anion and cation exchange chromatography, is utilized for routine separation of carrier-free (225)Ac from a mixture of (228)Th, (229)Th and (232)Th. The separation of Ra and Ac from Th is achieved using the marcoporous anion exchange resin MP1 in 8M HNO(3) media. Two sequential MP1/NO(3) columns provide a separation factor of approximately 10(6) for Ra and Ac from Th. The separation of Ac from Ra is accomplished on a low cross-linking cation exchange resin AG50-X4 using 1.2M HNO(3) as eluant. Two sequential AG50/NO(3) columns provide a separation factor of approximately 10(2) for Ac from Ra. A 60-day processing schedule has been adopted in order to reduce the processing cost and to provide the highest levels of (225)Ac possible. Over an 8-week campaign, a total of approximately 100 mCi of (225)Ac (approximately 80% of the theoretical yield) is shipped in 5-6 batches, with the first batch typically consisting of approximately 50 mCi. After the initial separation and purification of Ac, the Ra pool is re-processed on a bi-weekly schedule or as needed to provide smaller batches of (225)Ac. The averaged radioisotopic purity of the (225)Ac was 99.6 +/- 0.7% with a (225)Ra content of < or =0.6%, and an average (229)Th content of (4(-4)(+5)) x 10(-5)%.

  6. Volumetric Behaviour of the (2,2,4-Trimethylpentane + Methylbenzene + Butan-1-ol) Ternary System and Its Binary Sub-Systems within the Temperature Range (298.15–328.15) K

    OpenAIRE

    Morávková, L. (Lenka); Troncoso, J.; Machanová, K. (Karolina); Sedláková, Z.

    2013-01-01

    Densities and speeds of sound of the (2,2,4-trimethylpentane + methylbenzene + butan-1-ol) ternary system as well as all its binary sub-systems were measured at four temperatures, namely 298.15 K, 308.15 K, 318.15 K, and 328.15 K at atmospheric pressure by a vibrating-tube densimeter DSA 5000. The binary (isooctane + toluene) system was studied previously. Excess quantities (molar volume, adiabatic compressibility, and isobaric thermal expansivity) of the mixtures studied were calculated from...

  7. Occurrence of Radium-224, Radium-226 and Radium-228 in Water from the Vincentown and Wenonah-Mount Laurel Aquifers, the Englishtown Aquifer System, and the Hornerstown and Red Bank Sands, Southwestern and South-Central New Jersey

    Science.gov (United States)

    dePaul, Vincent T.; Szabo, Zoltan

    2007-01-01

    This investigation is the first regionally focused study of the presence of natural radioactivity in water from the Vincentown and Wenonah-Mount Laurel aquifers, Englishtown aquifer system, and the Hornerstown and Red Bank Sands. Geologic materials composing the Vincentown and Wenonah-Mount Laurel aquifers and the Hornerstown and Red Bank Sands previously have been reported to contain radioactive (uranium-enriched) phosphatic strata, which is common in deposits from some moderate-depth coastal marine environments. The decay of uranium and thorium gives rise to natural radioactivity and numerous radioactive progeny, including isotopes of radium. Naturally occurring radioactive isotopes, especially those of radium, are of concern because radium is a known human carcinogen and ingestion (especially in water used for drinking) can present appreciable health risks. A regional network in southwestern and south-central New Jersey of 39 wells completed in the Vincentown and Wenonah-Mount Laurel aquifers, the Englishtown aquifer system, and the Hornerstown and Red Bank Sands was sampled for determination of gross alpha-particle activity; concentrations of radium radionuclides, major ions, and selected trace elements; and physical properties. Concentrations of radium-224, radium-226, and radium-228 were determined for water from 28 of the 39 wells, whereas gross alpha-particle activity was determined for all 39. The alpha spectroscopic technique was used to determine concentrations of radium-224, which ranged from less than 0.5 to 2.7 pCi/L with a median concentration of less than 0.5pCi/L, and of radium-226, which ranged from less than 0.5 to 3.2 pCi/L with a median concentration of less than 0.5 pCi/L. The beta-counting technique was used to determine concentrations of radium-228. The concentration of radium-228 ranged from less than 0.5 to 4.3 pCi/L with a median of less than 0.5. Radium-228, when quantifiable, had the greatest concentration of the three radium

  8. Synthesis, antifungal activities and molecular docking studies of novel 2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl dithiocarbamates.

    Science.gov (United States)

    Zou, Yan; Yu, Shichong; Li, Renwu; Zhao, Qingjie; Li, Xiang; Wu, Maocheng; Huang, Ting; Chai, Xiaoxun; Hu, Honggang; Wu, Qiuye

    2014-03-01

    A series of 2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl dithiocarbamates as new analogs of fluconazole were synthesized and their antifungal activities were evaluated. Among these compounds, 2a-f and 3a-q exhibited higher activities than fluconazole against nearly all fungi tested except Aspergillus fumigatus. Noticeably, the in vitro biological activities of 2b, 3a, 3c, 3h-k, and 3o-q against Candida species were much better than those of fluconazole and ketoconazole. Also, 2a-d, 3a-d, 3e-f, 3h-k, 3p and 3q showed higher activities against A. fumi than fluconazole. Computational docking experiments indicated that the inhibition of CYP51 involved a coordination bond with iron of the heme group, the hydrophilic H-bonding region, the hydrophobic region, and the narrow hydrophobic cleft. PMID:24487187

  9. Support vector classification for structure-activity-relationship of 1-(1H-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-substituted-2-propanols%支持向量分类算法用于1-(1H-1,2,4-三唑-1-基)-2-(2,4-二氟苯基)-3-取代-2-丙醇化合物的构效关系研究

    Institute of Scientific and Technical Information of China (English)

    纪晓波; 陆文聪; 蔡煜东; 陈念贻

    2007-01-01

    The support vector classification (SVC) was employed to make a model for classification of antifungal activities of 1-(1H-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-substituted-2-propanols triazole derivatives. The compounds with high antifungal activities and those with low antifungal activities were compared on the basis of the following molecular descriptors: net atomic charge on the atom N connecting with R, dipole moment and heat of formation. By using the SVC, a mathematical model was constructed, which can predict the antifungal activities of the triazole derivatives, with an accuracy of 91% on the basis of the leave-one-out cross-validation (LOOCV) test. The results indicate that the performance of the SVC model can exceed that of the principal component analysis (PCA) and K-Nearest Neighbor (KNN) models for this real world data set.

  10. New derivative of 2-(2,4-dihydroxyphenyl)thieno-1,3-thiazin-4-one (BChTT) elicits antiproliferative effect via p38-mediated cell cycle arrest in cancer cells.

    Science.gov (United States)

    Juszczak, Małgorzata; Walczak, Katarzyna; Matysiak, Joanna; Lemieszek, Marta K; Langner, Ewa; Karpińska, Monika M; Pożarowski, Piotr; Niewiadomy, Andrzej; Rzeski, Wojciech

    2016-03-15

    2-(2,4-Dihydroxyphenyl)thieno-1,3-thiazin-4-ones are a group of new compounds with potential anticancer activity. This type of derivatives was poorly investigated in the area of synthesis and biological activities. In the present study the antiproliferative action of the most active derivative BChTT was described. The aim of biological evaluation was to investigate the ability of the compound to inhibit cancer cell proliferation and identify mechanism involved in its action on the molecular level. BChTT inhibited the proliferation of lung cancer A549, colon cancer HT-29 and glioma C6 cells in the concentration-dependent manner. It was not toxic to normal cells including skin fibroblasts, hepatocytes and oligodendrocytes in the antiproliferative concentrations. BChTT decreased the DNA synthesis in the treated cancer cells and induced cell cycle arrest in the G0/G1 phase. Moreover, the ability of the compound to activate p38 kinase and decrease cyclin D1 expression was estimated. Participation of p38 kinase in the antiproliferative action of the compound was confirmed by the analysis of BChTT activity in the cells with the p38 silenced gene. The obtained results may suggest the ability of the tested derivative to inhibit cancer cells proliferation by induction of p38-mediated cyclin D1 downregulation.

  11. Synthesis, growth, structural, optical, luminescence, surface and HOMO LUMO analysis of 2-[2-(4-cholro-phenyl)-vinyl]-1-methylquinolinium naphthalene-2-sulfonate organic single crystals grown by a slow evaporation technique

    Science.gov (United States)

    Karthigha, S.; Kalainathan, S.; Maheswara Rao, Kunda Uma; Hamada, Fumio; Yamada, Manabu; Kondo, Yoshihiko

    2016-02-01

    Single crystals of 2-[2-(4-cholro-phenyl)-vinyl]-1-methylquinolinium naphthalene-2-sulfonate (4CLNS) were grown by a slow evaporation technique. The formation of molecule was confirmed from 1H NMR and FTIR analysis. The confirmation of crystal structure was done by single crystal XRD and atomic packing of grown crystal was identified. The grown single crystal crystallized in triclinic structure with centrosymmetric space group P-1. The crystalline nature of the synthesised material was recorded by powder XRD. The optical absorption properties of the grown crystals were analyzed by UV-vis spectral studies. The thermal behaviour of the title material has been studied by TG/DTA analysis which revealed the stability of the compound till its melting point 276.7 °C. The third order nonlinear optical property of 4CLNS was investigated in detail by Z scan technique and it confirms that the title crystal is suitable for photonic devices and NLO optical applications. Emissions at 519 nm in green region of the EM spectrum were found by photoluminescence studies. The charge transfer occurring within the molecule is explained by the calculated HOMO and LUMO energies.

  12. Participant and spectator scaling of spectator fragments in Au + Au and Cu + Cu collisions at √{sN N}=19.6 and 22.4 GeV

    Science.gov (United States)

    Alver, B.; Back, B. B.; Baker, M. D.; Ballintijn, M.; Barton, D. S.; Betts, R. R.; Bickley, A. A.; Bindel, R.; Budzanowski, A.; Busza, W.; Carroll, A.; Chai, Z.; Chetluru, V.; Decowski, M. P.; García, E.; Gburek, T.; George, N.; Gulbrandsen, K.; Gushue, S.; Halliwell, C.; Hamblen, J.; Harnarine, I.; Heintzelman, G. A.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Katzy, J.; Khan, N.; Kucewicz, W.; Kulinich, P.; Kuo, C. M.; Li, W.; Lin, W. T.; Loizides, C.; Manly, S.; McLeod, D.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Park, I. C.; Pernegger, H.; Reed, C.; Remsberg, L. P.; Reuter, M.; Richardson, E.; Roland, C.; Roland, G.; Rosenberg, L.; Sagerer, J.; Sarin, P.; Sawicki, P.; Sedykh, I.; Skulski, W.; Smith, C. E.; Stankiewicz, M. A.; Steinberg, P.; Stephans, G. S. F.; Sukhanov, A.; Szostak, A.; Tang, J.-L.; Tonjes, M. B.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Vaurynovich, S. S.; Verdier, R.; Veres, G. I.; Walters, P.; Wenger, E.; Willhelm, D.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wuosmaa, A. H.; Wyngaardt, S.; Wysłouch, B.; Phobos Collaboration

    2016-08-01

    Spectator fragments resulting from relativistic heavy ion collisions, consisting of single protons and neutrons along with groups of stable nuclear fragments up to nitrogen (Z =7 ), are measured in PHOBOS. These fragments are observed in Au+Au (√{sNN}=19.6 GeV ) and Cu+Cu (22.4 GeV) collisions at high pseudorapidity (η ). The dominant multiply-charged fragment is the tightly bound helium (α ), with lithium, beryllium, and boron all clearly seen as a function of collision centrality and pseudorapidity. We observe that in Cu+Cu collisions, it becomes much more favorable for the α fragments to be released than lithium. The yields of fragments approximately scale with the number of spectator nucleons, independent of the colliding ion. The shapes of the pseudorapidity distributions of fragments indicate that the average deflection of the fragments away from the beam direction increases for more central collisions. A detailed comparison of the shapes for α and lithium fragments indicates that the centrality dependence of the deflections favors a scaling with the number of participants in the collision.

  13. Participant and spectator scaling of spectator fragments in Au+Au and Cu+Cu collisions at sqrt(sNN) = 19.6 and 22.4 GeV

    CERN Document Server

    Alver, B; Baker, M D; Ballintijn, M; Barton, D S; Betts, R R; Bickley, A A; Bindel, R; Budzanowski, A; Busza, W; Carroll, A; Chai, Z; Chetluru, V; Decowski, M P; Garcia, E; Gburek, T; George, N; Gulbrandsen, K; Gushue, S; Halliwell, C; Hamblen, J; Harnarine, I; Heintzelman, G A; Henderson, C; Hofman, D J; Hollis, R S; Holynski, R; Holzman, B; Iordanova, A; Johnson, E; Kane, J L; Katzy, J; Khan, N; Kucewicz, W; Kulinich, P; Kuo, C M; Li, W; Lin, W T; Loizides, C; Manly, S; McLeod, D; Mignerey, A C; Nouicer, R; Olszewski, A; Pak, R; Park, I C; Pernegger, H; Reed, C; Remsberg, L P; Reuter, M; Richardson, E; Roland, C; Roland, G; Rosenberg, L; Sagerer, J; Sarin, P; Sawicki, P; Sedykh, I; Skulski, W; Smith, C E; Stankiewicz, M A; Steinberg, P; Stephans, G S F; Sukhanov, A; Szostak, A; Tang, J L; Tonjes, M B; Trzupek, A; Vale, C; van Nieuwenhuizen, G J; Vaurynovich, S S; Verdier, R; Veres, G I; Walters, P; Wenger, E; Willhelm, D; Wolfs, F L H; Wosiek, B; Wozniak, K; Wuosmaa, A H; Wyngaardt, S; Wyslouch, B

    2015-01-01

    Spectator fragments resulting from relativistic heavy ion collisions, consisting of single protons and neutrons along with groups of stable nuclear fragments up to Nitrogen (Z=7), are measured in PHOBOS. These fragments are observed in Au+Au (sqrt(sNN)=19.6 GeV) and Cu+Cu (22.4 GeV) collisions at high pseudorapidity ($\\eta$). The dominant multiply-charged fragment is the tightly bound Helium ($\\alpha$), with Lithium, Beryllium, and Boron all clearly seen as a function of collision centrality and pseudorapidity. We observe that in Cu+Cu collisions, it becomes much more favorable for the $\\alpha$ fragments to be released than Lithium. The yields of fragments approximately scale with the number of spectator nucleons, independent of the colliding ion. The shapes of the pseudorapidity distributions of fragments indicate that the average deflection of the fragments away from the beam direction increases for more central collisions. A detailed comparison of the shapes for $\\alpha$ and Lithium fragments indicates tha...

  14. Contiguous 2,2,4-triamino-5(2H)-oxazolone obstructs DNA synthesis by DNA polymerases α, β, η, ι, κ, REV1 and Klenow Fragment exo-, but not by DNA polymerase ζ.

    Science.gov (United States)

    Suzuki, Masayo; Kino, Katsuhito; Kawada, Taishu; Oyoshi, Takanori; Morikawa, Masayuki; Kobayashi, Takanobu; Miyazawa, Hiroshi

    2016-03-01

    Guanine is the most easily oxidized of the four DNA bases, and contiguous guanines (GG) in a sequence are more readily oxidized than a single guanine in a sequence. Continued oxidation of GGs results in a contiguous oxidized guanine lesion. Two contiguous 2,5-diamino-4H-imidazol-4-ones, an oxidized form of guanine that hydrolyses to 2,2,4-triamino-5(2H)-oxazolone (Oz), are detected following the oxidation of GG. In this study, we analysed translesion synthesis (TLS) across two contiguous Oz molecules (OzOz) using Klenow Fragment exo(-) (KF exo(-)) and DNA polymerases (Pols) α, β, ζ, η, ι, κ and REV1. We found that KF exo(-) and Pols α, β, ι and REV1 inserted one nucleotide opposite the 3' Oz of OzOz and stalled at the subsequent extension, and that Pol κ incorporated no nucleotide. Pol η only inefficiently elongated the primer up to full-length across OzOz; the synthesis of most DNA strands stalled at the 3' or 5' Oz of OzOz. Surprisingly, however, Pol ζ efficiently extended the primer up to full-length across OzOz, unlike the other DNA polymerases, but catalysed error-prone nucleotide incorporation. We therefore believe that Pol ζ is required for efficient TLS of OzOz. These results show that OzOz obstructs DNA synthesis by DNA polymerases except Pol ζ.

  15. Catalytic performance of Fe3O4-CoO/Al2O3 catalyst in ozonation of 2-(2,4-dichlorophenoxy) propionic acid,nitrobenzene and oxalic acid in water

    Institute of Scientific and Technical Information of China (English)

    Shaoping Tong; Rui Shi; Hua Zhang; Chunan Ma

    2010-01-01

    the precursors,and its catalytic performance was investigated in ozonation of 2-(2,4-dichlorophenoxy) propionic acid (2,4-DP),nitrobenzene and oxalic acid.The experimental results indicated that Fe3O4-CoO/Al2O3 catalyst enabled an interesting improvement of ozonation efficiency during the degradation of each organic pollutant,and the Fe3O4-CoO/Al2O3 catalytic ozonation system followed a radical-type mechanism.The kinetics of ozonation alone and Fe3O4-CoO/Al2O3 catalytic ozonation of three organic pollutants in aqueous solution were discussed under the mere consideration of direct ozone reaction and OH radical reaction to well investigate its performance.In the catalytic ozonation of 2,4-DP,the apparent reaction rate constants (k) were determined to be 1.456×10-2 min-1 for ozonation alone and 4.740×10-2 min-1 for O3/Fe3O4-CoO/Al2O3.And O3/Fe3O4-CoO/Al2O3 had a larger Rct (6.614×10-9) calculated by the relative method than O3 did (1.800×10-9),showing O3/Fe3O4-CoO/Al2O3 generated more hydroxyl radical.Similar results were also obtained in the catalytic ozonation of nitrobenzene and oxalic acid.The above results demonstrated that the catalytic performance of Fe3O4-CoO/Al2O3 in ozonation of studied organic substance was universal to a certain degree.

  16. INDEPENDENT VERIFICATION SURVEY REPORT FOR EXPOSURE UNITS Z2-24, Z2-31, Z2-32, AND Z2-36 IN ZONE 2 OF THE EAST TENNESSEE TECHNOLOGY PARK OAK RIDGE, TENNESSEE

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-10-10

    The U.S. Department of Energy (DOE) Oak Ridge Office of Environmental Management selected Oak Ridge Associated Universities (ORAU), through the Oak Ridge Institute for Science and Education (ORISE) contract, to perform independent verification (IV) at Zone 2 of the East Tennessee Technology Park (ETTP) in Oak Ridge, Tennessee. ORAU has concluded IV surveys, per the project-specific plan (PSP) (ORAU 2013a) covering exposure units (EUs) Z2-24, -31, -32, and -36. The objective of this effort was to verify the following. • Target EUs comply with requirements in the Zone 2 Record of Decision (ROD) (DOE 2005), as implemented by using the dynamic verification strategy presented in the dynamic work plan (DWP) (BJC 2007) • Commitments in the DWP were adequately implemented, as verified via IV surveys and soil sampling The Zone 2 ROD establishes maximum remediation level (RLmax) values and average RL (RLavg) values for the primary contaminants of concern (COCs) U-234, U-235, U-238, Cs-137, Np-237, Ra-226, Th-232, arsenic, mercury, and polychlorinated biphenyls (PCBs). Table 1.1 lists Zone 2 COCs with associated RLs. Additional radiological and chemical contaminants were also identified during past characterization and monitoring actions, though the ROD does not present RLs for these potential contaminants. IV activities focused on the identification and quantification of ROD-specific COCs in surface soils, but also generated data for other analytes to support future decisions. ORAU personnel also reviewed EU-specific phased construction completion reports (PCCRs) to focus IV activities and identify potential judgmental sample locations, if any.

  17. 31 CFR 800.224 - Transaction.

    Science.gov (United States)

    2010-07-01

    ... SECURITY, DEPARTMENT OF THE TREASURY REGULATIONS PERTAINING TO MERGERS, ACQUISITIONS, AND TAKEOVERS BY... merger, acquisition, or takeover. It includes: (a) The acquisition of an ownership interest in an entity. (b) The acquisition or conversion of convertible voting instruments of an entity. (c) The...

  18. 22 CFR 224.21 - Discovery.

    Science.gov (United States)

    2010-04-01

    ....21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of... document or the truth of any relevant fact; (3) Written interrogatories; and (4) Depositions. (b) For...

  19. CopperCore 2.2.4

    NARCIS (Netherlands)

    Vogten, Hubert; Martens, Harrie; Koper, Rob

    2005-01-01

    Changed in this release: -fixed bug with the id of the Monitor object and other services, fixed bugs with regard to the visibility of items. Please go to SourceForge for the original sources and website (this is only a backup archive): http://coppercore.sourceforge.net/ Available under the GNU GPL l

  20. 22 CFR 224.33 - Witnesses.

    Science.gov (United States)

    2010-04-01

    ....33 Witnesses. (a) Except as provided in paragraph (b) of this section, testimony at the hearing shall be given orally by witnesses under oath or affirmation. (b) At the discretion of the ALJ, testimony... provided to all other parties along with the last known address of such witness, in a manner which...

  1. 22 CFR 224.2 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... respect to a claim or statement— (a) Has actual knowledge that the claim or statement is false, fictitious... the General Schedule. Statement means any representation, certification, affirmation, document,...

  2. Purification of selenium from thorium, uranium, radium, actinium and potassium impurities for low background measurements

    International Nuclear Information System (INIS)

    A technique of selenium purification from 232Th, 238U, 226,228Ra, 227Ac and 40K was developed. This technique is simple to perform and employs a minimum number of highly pure reagents (bidistilled water, nitric acid). Operations carried out during purification (elution, evaporation) practically exclude losses of the target product (chemical yields of Se > 99%). A test purification of 100 g of selenium was carried out using this technique. The efficiency of this technique was confirmed by low background gamma spectrometry of the purified selenium sample. Distribution coefficients of Th, U, Ra and Ac on DOWEX 50W- x 8 cation-exchange resin at different concentrations of selenium and nitric acid were experimentally determinated. Instrumental neutron activation analysis of bidistilled water, deionized water and nitric acid was performed. (orig.)

  3. Radium-228 analysis of natural waters by Cherenkov counting of Actinium-228

    Energy Technology Data Exchange (ETDEWEB)

    Aleissa, Khalid A.; Almasoud, Fahad I.; Islam, Mohammed S. [Atomic Energy Research Institute, King Abdul Aziz City for Science and Technology, P.O. Box 6086, Riyadh 11442 (Saudi Arabia); L' Annunziata, Michael F. [IAEA Expert, Montague Group, P.O. Box 5033, Oceanside, CA 92052-5033 (United States)], E-mail: mlannunziata@cox.net

    2008-12-15

    The activities of {sup 228}Ra in natural waters were determined by the Cherenkov counting of the daughter nuclide {sup 228}Ac. The radium was pre-concentrated on MnO{sub 2} and the radium purified via ion exchange and, after a 2-day period of incubation to allow for secular equilibrium between the parent-daughter {sup 228}Ra({sup 228}Ac), the daughter nuclide {sup 228}Ac was isolated by ion exchange according to the method of Nour et al. [2004. Radium-228 determination of natural waters via concentration on manganese dioxide and separation using Diphonix ion exchange resin. Appl. Radiat. Isot. 61, 1173-1178]. The Cherenkov photons produced by {sup 228}Ac were counted directly without the addition of any scintillation reagents. The optimum Cherenkov counting window, sample volume, and vial type were determined experimentally to achieve optimum Cherenkov photon detection efficiency and lowest background count rates. An optimum detection efficiency of 10.9{+-}0.1% was measured for {sup 228}Ac by Cherenkov counting with a very low Cherenkov photon background of 0.317{+-}0.013 cpm. The addition of sodium salicylate into the sample counting vial at a concentration of 0.1 g/mL yielded a more than 3-fold increase in the Cherenkov detection efficiency of {sup 228}Ac to 38%. Tests of the Cherenkov counting technique were conducted with several water standards of known activity and the results obtained compared closely with a conventional liquid scintillation counting technique. The advantages and disadvantages of Cherenkov counting compared to liquid scintillation counting methods are discussed. Advantages include much lower Cherenkov background count rates and consequently lower minimal detectable activities for {sup 228}Ra and no need for expensive environmentally unfriendly liquid scintillation cocktails. The disadvantages of the Cherenkov counting method include the need to measure {sup 228}Ac Cherenkov photon detection efficiency and optimum Cherenkov counting volume, which are not at all required when liquid scintillation analysis is used.

  4. Radium-228 analysis of natural waters by Cherenkov counting of Actinium-228.

    Science.gov (United States)

    Aleissa, Khalid A; Almasoud, Fahad I; Islam, Mohammed S; L'Annunziata, Michael F

    2008-12-01

    The activities of (228)Ra in natural waters were determined by the Cherenkov counting of the daughter nuclide (228)Ac. The radium was pre-concentrated on MnO(2) and the radium purified via ion exchange and, after a 2-day period of incubation to allow for secular equilibrium between the parent-daughter (228)Ra((228)Ac), the daughter nuclide (228)Ac was isolated by ion exchange according to the method of Nour et al. [2004. Radium-228 determination of natural waters via concentration on manganese dioxide and separation using Diphonix ion exchange resin. Appl. Radiat. Isot. 61, 1173-1178]. The Cherenkov photons produced by (228)Ac were counted directly without the addition of any scintillation reagents. The optimum Cherenkov counting window, sample volume, and vial type were determined experimentally to achieve optimum Cherenkov photon detection efficiency and lowest background count rates. An optimum detection efficiency of 10.9+/-0.1% was measured for (228)Ac by Cherenkov counting with a very low Cherenkov photon background of 0.317+/-0.013cpm. The addition of sodium salicylate into the sample counting vial at a concentration of 0.1g/mL yielded a more than 3-fold increase in the Cherenkov detection efficiency of (228)Ac to 38%. Tests of the Cherenkov counting technique were conducted with several water standards of known activity and the results obtained compared closely with a conventional liquid scintillation counting technique. The advantages and disadvantages of Cherenkov counting compared to liquid scintillation counting methods are discussed. Advantages include much lower Cherenkov background count rates and consequently lower minimal detectable activities for (228)Ra and no need for expensive environmentally unfriendly liquid scintillation cocktails. The disadvantages of the Cherenkov counting method include the need to measure (228)Ac Cherenkov photon detection efficiency and optimum Cherenkov counting volume, which are not at all required when liquid scintillation analysis is used.

  5. Purification of selenium from thorium, uranium, radium, actinium and potassium impurities for low background measurements

    Energy Technology Data Exchange (ETDEWEB)

    Rakhimov, A.V. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Uzbek Academy of Sciences, Tashkent (Uzbekistan). Inst. of Nuclear Physics (INP AS RUz); Warot, G. [CEA-CNRS, Modane (France). Laboratoire Souterrain de Modane (LSM); Karaivanov, D.V. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Institute for Nuclear Research and Nuclear Energy (INRNE), Sofia (Bulgaria); Kochetov, O.I.; Lebedev, N.A.; Filosofov, D.V. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Mukhamedshina, N.M.; Sadikov, I.I. [Uzbek Academy of Sciences, Tashkent (Uzbekistan). Inst. of Nuclear Physics (INP AS RUz)

    2013-07-01

    A technique of selenium purification from {sup 232}Th, {sup 238}U, {sup 226,228}Ra, {sup 227}Ac and {sup 40}K was developed. This technique is simple to perform and employs a minimum number of highly pure reagents (bidistilled water, nitric acid). Operations carried out during purification (elution, evaporation) practically exclude losses of the target product (chemical yields of Se > 99%). A test purification of 100 g of selenium was carried out using this technique. The efficiency of this technique was confirmed by low background gamma spectrometry of the purified selenium sample. Distribution coefficients of Th, U, Ra and Ac on DOWEX 50W- x 8 cation-exchange resin at different concentrations of selenium and nitric acid were experimentally determinated. Instrumental neutron activation analysis of bidistilled water, deionized water and nitric acid was performed. (orig.)

  6. Linear free energy relationship applied to trivalent cations with lanthanum and actinium oxide and hydroxide structure

    International Nuclear Information System (INIS)

    Linear free energy relationships for trivalent cations with crystalline M2O3 and, M(OH)3 phases of lanthanides and actinides were developed from known thermodynamic properties of the aqueous trivalent cations, modifying the Sverjensky and Molling equation. The linear free energy relationship for trivalent cations is as ΔGf,MvX0=aMvXΔGn,M3+0+bMvX+βMvXrM3+, where the coefficients aMvX, bMvX, and βMvX characterize a particular structural family of MvX, rM3+ is the ionic radius of M3+ cation, ΔGf,MvX0 is the standard Gibbs free energy of formation of MvX and ΔGn,M3+0 is the standard non-solvation free energy of the cation. The coefficients for the oxide family are: aMvX=0.2705, bMvX=-1984.75 (kJ/mol), and βMvX=197.24 (kJ/molnm). The coefficients for the hydroxide family are: aMvX=0.1587, bMvX=-1474.09 (kJ/mol), and βMvX=791.70 (kJ/molnm).

  7. Actinium: A RESTful Runtime Container for Scriptable Internet of Things Applications

    OpenAIRE

    Kovatsch, Matthias; Lanter, Martin; Duquennoy, Simon

    2012-01-01

    Programming Internet of Things (IoT) applications is challenging because developers have to be knowledgeable in various technical domains, from low-power networking, over embedded operating systems, to distributed algorithms. Hence, it will be challenging to find enough experts to provide software for the vast number of expected devices, which must also be scalable and particularly safe due to the connection to the physical world. To remedy this situation, we propose an architecture that pr...

  8. Bestimmung der Ionisationsenergie von Actinium und Ultraspurenanalyse von Plutonium mit resonanter Ionisationsmassenspektrometrie (RIMS)

    OpenAIRE

    Waldek, Achim Marcus

    2001-01-01

    ZusammenfassungDie Resonanzionisationsmassenspektrometrie (RIMS) verbindet hohe Elementselektivität mit guter Nachweiseffizienz. Aufgrund dieser Eigenschaften ist die Methode für Ultraspurenanalyse und Untersuchungen an seltenen oder schwer handhabbaren Elementen gut geeignet. Für RIMS werden neutrale Atome mit monochromatischem Laserlicht ein- oder mehrfach resonant auf energetisch hoch liegende Niveaus angeregt und anschließend durch einen weiteren Laserstrahl oder durch ein elektrisches Fe...

  9. New method for large scale production of medically applicable Actinium-225 and Radium-223

    International Nuclear Information System (INIS)

    Alpha-emitters (211At, 212Bi, 213Bi, 223Ra, 225Ac) are promising for targeted radiotherapy of cancer. Only two alpha decays near a cell membrane result in 50% death of cancer cell and only a single decay inside the cell is required for this. 225Ac may be used either directly or as a mother radionuclide in 213Bi isotope generator. Production of 225Ac is provided by three main suppliers - Institute for Transuranium Elements in Germany, Oak Ridge National Laboratory in USA and Institute of Physics and Power Engineering in Obninsk, Russia. The current worldwide production of 225Ac is approximately 1.7 Ci per year that corresponds to only 100-200 patients that could be treated annually. The common approach for 225Ac production is separation from mother 229Th or irradiation of 226Ra with protons in a cyclotron. Both the methods have some practical limitations to be applied routinely. 225Ac can be also produced by irradiation of natural thorium with medium energy protons . Cumulative cross sections of 225Ac, 227Ac, 227Th, 228Th formations have been obtained recently. Thorium targets (1-9 g) were irradiated by 114-91 MeV proton beam (1-50 μA) at INR linear accelerator. After dissolution in 8 M HNO3 + 0.004 M HF thorium was removed by double LLX by HDEHP in toluene (1:1). Ac and REE were pre-concentrated and separated from Ra and most fission products by DGA-Resin (Triskem). After washing out by 0.01 M HNO3 Ac was separated from REE by TRU Resin (Triskem) in 3 M HNO3 media. About 6 mCi 225Ac were separated in hot cell with chemical yield 85%. The method may be upscaled for production of Ci amounts of the radionuclide. The main impurity is 227Ac (0.1% at the EOB) but it does not hinder 225Ac from being used for medical 225Ac/213Bi generators. (author)

  10. Dicty_cDB: VSI224 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available yk mek*e*iy*w*ntsc*ifkkemgkrg*i*tn*rvvdissw***ncrqici*merfkw*lv *iiwk*klgiq*iwsngsktcink*sln**itkiislamr*kt*...*iy*w*ntsc*ifkkemgkrg*i*tn*rvvdissw***ncrqici*me rfkw*lv*iiwk*klgiq*iwsngsktcink*sln**itkiislamr*kt**sskfirf

  11. 7 CFR 2.24 - Assistant Secretary for Administration.

    Science.gov (United States)

    2010-01-01

    ... CFR, 1978 Comp., p. 243); (H) Implementation of the Uniform Relocation Assistance and Real Property... Populations and Low-Income Populations. (xv) Take such action as may be necessary, with the affected agency... disposing of real and personal property, including control of space assignments; (B) Acquiring,...

  12. Editorial [Malta Medical Journal, Vol.22(4)

    OpenAIRE

    Vassallo, Josanne

    2010-01-01

    Another publication year has come to an end and I note with pleasure the diversity of papers that have been submitted over the course of the past year. The papers are of particular interest to the medical community in the Maltese islands. A survey dealing with the aetiology of infectious intestinal disease provides information of relevance to practitioners in Malta.

  13. Dicty_cDB: AFO224 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ksck*ey snr*slrftrketllqsw*t*cscp*t*lcrpir*syrkrsfithllwyskw*fcnfthc wcsswyrn*thr*w*nyn*rccwssns*ilftnfrei...ki*ni Frame B: fkknhlgnlkifnikk*kksflttfvyaeekkrnekyiiirfwlcckast*lplkkrrlf cnnc*fi

  14. 49 CFR 224.105 - Sheeting dimensions and quantity.

    Science.gov (United States)

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REFLECTORIZATION OF RAIL FREIGHT ROLLING STOCK Application.... Retroreflective sheeting shall be applied along the length of each railroad freight car and locomotive side as... gear. Each side of a railroad freight car subject to this part, including each unit of multi-unit...

  15. 49 CFR 224.106 - Location of retroreflective sheeting.

    Science.gov (United States)

    2010-10-01

    ... ladders and other safety appliances, pipes, or other attachments that may obscure its visibility... each car side. (b) Locomotives. Locomotives subject to this part shall be equipped with at least the... or 36 inches long and spaced as uniformly as practicable along the length of the locomotive sides,...

  16. Organizing to Work with CETA. Information Series No. 224.

    Science.gov (United States)

    Jacobson, Thomas J.

    This paper traces Comprehensive Employment and Training Act (CETA) vocational education coordination activities that have occurred in the past and provides suggestions for activities that can be pursued at the local school district level to help school districts participate in the funding opportunities available under CETA. It is designed for…

  17. Dicty_cDB: AFH224 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ficant alignments: (bits) Value N BI315670 |BI315670.1 saf75f12.y1 Gm-c1078 Glycine max cDNA clone GENOME SYSTEMS... CLONEINHIBITOR. ;, mRNA sequence. 56 5e-06 2 AI437629 |AI437629.1 sa37e09.y1 Gm-c1004 Glycine max cDNA clone GENOME SYSTEMS... BE800797 |BE800797.1 sq98c12.y1 Gm-c1049 Glycine max cDNA clone GENOME SYSTEMS C... 1 AW397479 |AW397479.1 sg79d05.y1 Gm-c1007 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1007-2626 5'...04 1 BG790353 |BG790353.1 sae68c10.y1 Gm-c1064 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1064-3212

  18. Dicty_cDB: CHE224 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SDVKFLNTPHFELPPNANPGDFLR ETFDHPSAPKALEFAHGTTTLAFVYGGGIIVSXDSKSTQGPY--- ---rthlccccx*nfskxxifi*rxrfingxydywlg...*nwtxiilc***wd*itwstffm wxrfnxxlwcfxxrf*mgye*xxsi*trsxsclscnsqxxllwwxyqclscskrwle...fkyttfrittkcksr*ffkr ni*ssistksigictwynyisiciwwryycixrfkiytrtir--- ---nssllllhxkf*qxlxihikxtvyqwxl*llvgikldx...nyimlimmgldymvnvfhv xqvqxmxmvfxxqvlngi*mxxkhmnsvxxlfimqltxxltlvxlsmfimfkkmvgxrfl lmixsnxixnitilxqlinqxn*xqxl

  19. 29 CFR 779.224 - Common control in other cases.

    Science.gov (United States)

    2010-07-01

    ... discussed in §§ 779.225 through 779.235. Leased Departments, Franchise and Other Business Arrangements ... business activities with other persons or corporations. In such a case, the activities may be performed... arrangement between the parties so as to vest the control of the activities of one business in the hands...

  20. 抑郁症状与伤害发生特点的相关分析--基于1224例农村女性的横断面调查%A Cross-sectional Survey on the Correlation between Depressive Symptoms and Characteristics of Injury based on 1 224 Rural Women

    Institute of Scientific and Technical Information of China (English)

    帅健; 李丽萍; 方瑶; 陈业群; 熊建平; 张艳

    2013-01-01

    Objective To describe the occurrence of depressive symptoms and injury among rural women, and to explore the relationship between depressive symptoms and epidemiological characteristics of injury. Methods The study sample which was 1 224 rural women more than 18 years, from 22 places of Chaoshan district (Shantou, Chaozhou and Jieyang) of Guangdong province was got by cluster random sampling and investigated by Injuries information form and CES-D. The collected data was used to analyse the influence factors of depressive symptoms and the characters of injury through means of Chi-square test. Results Incidence of injuries was 8.01%, detection rate of depressive symptoms was 23.04%. The difference with respect to the quantity of samples with injuries did not have a statistical significance in different regions(P>0.05),but did in different age groups , states of marriage, occupation and education level(P0.05), but did in different states of marriage, occupation and education level(P0.05);未婚女性检出率(42.31%)、家务/离退休女性抑郁检出率(27.63%)、未接受教育女性的抑郁检出率(29.20%)较高,差异均有统计学意义(P<0.05)。有抑郁倾向组与无抑郁组在受伤种类、受伤性质、伤后处理和住院情况之间有差异。受伤性质中,有抑郁倾向组以骨折(40.00%)为主,无抑郁组为浅表损伤(50.60%);伤后处理中,有抑郁倾向组以门诊(40.00%)为主,无抑郁组为自己处理(32.53%);有抑郁倾向组严重伤害发生率(住院率46.67%)高于非抑郁组(6.02%)。结论农村女性表现出较高的伤害发生率和抑郁症状检出率,抑郁症状与伤害发生特点有一定的关联,应针对其特征采取相应的措施,促进农村女性的身心健康。

  1. Purification of radium-226 for the manufacturing of actinium-225 in a cyclotron for alpha-immunotherapy; Radium-Aufreinigung zur Herstellung von Actinium-225 am Zyklotron fuer die Alpha-Immuntherapie

    Energy Technology Data Exchange (ETDEWEB)

    Marx, Sebastian Markus

    2014-09-23

    The thesis describes the development of methods for the purification of Ra-226. The objective was to obtain the radionuclide in the quality that is needed to be used as starting material in the manufacturing process for Ac-225 via proton-irradiated Ra-226. The radionuclide has been gained efficiently out of huge excesses of impurities. The high purity of the obtained radium affords its use as staring material in a pharmaceutical manufacturing process.

  2. Renal uptake of bismuth-213 and its contribution to kidney radiation dose following administration of actinium-225-labeled antibody

    Energy Technology Data Exchange (ETDEWEB)

    Schwartz, J; O' Donoghue, J A; Humm, J L [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 (United States); Jaggi, J S [Bristol-Myers Squibb, Plainsboro, NJ (United States); Ruan, S; Larson, S M [Nuclear Medicine Service Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 (United States); McDevitt, M; Scheinberg, D A, E-mail: schwarj1@mskcc.org [Molecular Pharmacology and Chemistry, Sloan-Kettering Institute, 1275 York Avenue, New York, NY 10065 (United States)

    2011-02-07

    Clinical therapeutic studies using {sup 225}Ac-labeled antibodies have begun. Of major concern is renal toxicity that may result from the three alpha-emitting progeny generated following the decay of {sup 225}Ac. The purpose of this study was to determine the amount of {sup 225}Ac and non-equilibrium progeny in the mouse kidney after the injection of {sup 225}Ac-huM195 antibody and examine the dosimetric consequences. Groups of mice were sacrificed at 24, 96 and 144 h after injection with {sup 225}Ac-huM195 antibody and kidneys excised. One kidney was used for gamma ray spectroscopic measurements by a high-purity germanium (HPGe) detector. The second kidney was used to generate frozen tissue sections which were examined by digital autoradiography (DAR). Two measurements were performed on each kidney specimen: (1) immediately post-resection and (2) after sufficient time for any non-equilibrium excess {sup 213}Bi to decay completely. Comparison of these measurements enabled estimation of the amount of excess {sup 213}Bi reaching the kidney ({gamma}-ray spectroscopy) and its sub-regional distribution (DAR). The average absorbed dose to whole kidney, determined by spectroscopy, was 0.77 (SD 0.21) Gy kBq{sup -1}, of which 0.46 (SD 0.16) Gy kBq{sup -1} (i.e. 60%) was due to non-equilibrium excess {sup 213}Bi. The relative contributions to renal cortex and medulla were determined by DAR. The estimated dose to the cortex from non-equilibrium excess {sup 213}Bi (0.31 (SD 0.11) Gy kBq{sup -1}) represented {approx}46% of the total. For the medulla the dose contribution from excess {sup 213}Bi (0.81 (SD 0.28) Gy kBq{sup -1}) was {approx}80% of the total. Based on these estimates, for human patients we project a kidney-absorbed dose of 0.28 Gy MBq{sup -1} following administration of {sup 225}Ac-huM195 with non-equilibrium excess {sup 213}Bi responsible for approximately 60% of the total. Methods to reduce renal accumulation of radioactive progeny appear to be necessary for the success of {sup 225}Ac radioimmunotherapy.

  3. Validation of MIPAS IMK/IAA V5R_O3_224 ozone profiles

    Science.gov (United States)

    Laeng, A.; Grabowski, U.; von Clarmann, T.; Stiller, G.; Glatthor, N.; Höpfner, M.; Kellmann, S.; Kiefer, M.; Linden, A.; Lossow, S.; Sofieva, V.; Petropavlovskikh, I.; Hubert, D.; Bathgate, T.; Bernath, P.; Boone, C. D.; Clerbaux, C.; Coheur, P.; Damadeo, R.; Degenstein, D.; Frith, S.; Froidevaux, L.; Gille, J.; Hoppel, K.; McHugh, M.; Kasai, Y.; Lumpe, J.; Rahpoe, N.; Toon, G.; Sano, T.; Suzuki, M.; Tamminen, J.; Urban, J.; Walker, K.; Weber, M.; Zawodny, J.

    2014-11-01

    We present the results of an extensive validation program of the most recent version of ozone vertical profiles retrieved with the IMK/IAA (Institute for Meteorology and Climate Research/Instituto de Astrofísica de Andalucía) MIPAS (Michelson Interferometer for Passive Atmospheric Sounding) research level 2 processor from version 5 spectral level 1 data. The time period covered corresponds to the reduced spectral resolution period of the MIPAS instrument, i.e., January 2005-April 2012. The comparison with satellite instruments includes all post-2005 satellite limb and occultation sensors that have measured the vertical profiles of tropospheric and stratospheric ozone: ACE-FTS, GOMOS, HALOE, HIRDLS, MLS, OSIRIS, POAM, SAGE II, SCIAMACHY, SMILES, and SMR. In addition, balloon-borne MkIV solar occultation measurements and ground-based Umkehr measurements have been included, as well as two nadir sensors: IASI and SBUV. For each reference data set, bias determination and precision assessment are performed. Better agreement with reference instruments than for the previous data version, V5R_O3_220 (Laeng et al., 2014), is found: the known high bias around the ozone vmr (volume mixing ratio) peak is significantly reduced and the vertical resolution at 35 km has been improved. The agreement with limb and solar occultation reference instruments that have a known small bias vs. ozonesondes is within 7% in the lower and middle stratosphere and 5% in the upper troposphere. Around the ozone vmr peak, the agreement with most of the satellite reference instruments is within 5%; this bias is as low as 3% for ACE-FTS, MLS, OSIRIS, POAM and SBUV.

  4. Methyl (Z-2-[(2,4-dioxothiazolidin-3-ylmethyl]-3-(2-methylphenylprop-2-enoate

    Directory of Open Access Journals (Sweden)

    S. Vijayakumar

    2012-01-01

    Full Text Available The C=C bond in the title compound, C15H15NO4S, has a Z configuration. The thiazolidine ring is essentially planar [maximum deviation = 0.008 (1 Å for the N atom] and is oriented at a dihedral angle of 59.1 (1° with respect to the benzene ring. In the crystal, pairs of C—H...O hydrogen bonds link centrosymmetrically related molecules into dimers, generating R22(18 ring motifs. The crystal packing is further stabilized by C—H...π and C—O...π [O...centroid = 3.412 (2 Å and C—O...centroid = 115.0 (1°] interactions.

  5. 25 CFR 224.184 - How do other administrative appeals processes apply?

    Science.gov (United States)

    2010-04-01

    ... administrative appeals process in 25 CFR part 2 and 43 CFR part 4 are modified, only as they apply to appeals under this part, as set forth in this section. (a) The definition of interested party in 25 CFR part 2 and as incorporated in 43 CFR part 4 does not apply to this part. (b) The right of persons or...

  6. 50 CFR 224.101 - Enumeration of endangered marine and anadromous species.

    Science.gov (United States)

    2010-10-01

    ... the following: (a) Marine and anadromous fish. The following table lists the common and scientific... (Balaena mysticetus); Chinese river dolphin (Lipotes vexillifer); Cochito (Phocoena sinus); Fin or finback... novaeangliae); Indus River dolphin (Platanista minor); Mediterranean monk seal (Monachus monachus);...

  7. 25 CFR 166.224 - What factors does the BIA consider when reviewing a leasehold mortgage?

    Science.gov (United States)

    2010-04-01

    ... surety or guarantor; (2) The mortgage covers only the permit interest, and no unrelated collateral... order to protect the best interests of the Indian landowner. (b) In making the finding required...

  8. 2-[2-(4-Acetylphenylhydrazinylidene]-1,3-diphenylpropane-1,3-dione

    Directory of Open Access Journals (Sweden)

    Carlos Bustos

    2011-08-01

    Full Text Available In the title compound, C23H18N2O3, the interplanar angle between the benzoyl units is 80.51 (6° while the dihedral angles between the hydrazinylidene and benzoyl groups are 43.43 (6 and 54.16 (6°. In the crystal, a strong resonance-assisted intramolecular N—H...O hydrogen bond is observed. The molecules form an inversion dimer via a pair of weak C—H...O hydrogen bonds and a π–π interaction [centroid–centroid distance of 3.5719 (10 Å]. These dimers are linked via weak C—H...O contacts, forming chains along the b axis.

  9. 2-[2-(4-Nitrophenylhydrazinylidene]-1,3-diphenylpropane-1,3-dione

    Directory of Open Access Journals (Sweden)

    Carlos Bustos

    2011-07-01

    Full Text Available In the molecular structure of the title compound, C21H15N3O4, the interplanar angle between the benzoyl units is 89.7 (1°. The corresponding angles between the phenylhydrazono and the benzoyl groups are 31.4 (3 and 60.8 (2°, respectively. In the crystal, a strong resonance-assisted intramolecular hydrogen bond (N—H...O and a weak intramolecular hydrogen bond (C—H...N strongly affect the observed conformation of the molecule. The crystal packing is determined by a strong intermolecular hydrogen bond (N—H...O, giving rise to a helical chain along the a axis. In addition, two weak intermolecular contacts (C—H...O are observed.

  10. 2-[2-(4-Bromophenylhydrazinylidene]-1,3-diphenylpropane-1,3-dione

    Directory of Open Access Journals (Sweden)

    Carlos Bustos

    2011-06-01

    Full Text Available The conformation of the title molecule, C21H15BrN2O2, is stabilized by a weak intramolecular C—H...N hydrogen bond and a strong resonance-assisted N—H...O intramolecular hydrogen bond. In the crystal, the molecules are linked by weak intermolecular C—H...O interactions, forming zigzag chains along the b axis.

  11. Linear systems analysis program, L224(QR). Volume 2: Supplemental system design and maintenance document

    Science.gov (United States)

    Heidergott, K. W.

    1979-01-01

    The computer program known as QR is described. Classical control systems analysis and synthesis (root locus, time response, and frequency response) can be performed using this program. Programming details of the QR program are presented.

  12. Validation of MIPAS IMK/IAA V5R_O3_224 ozone profiles

    Directory of Open Access Journals (Sweden)

    A. Laeng

    2014-04-01

    Full Text Available We present the results of an extensive validation program of the most recent version of ozone vertical profiles retrieved with the IMK/IAA MIPAS research level 2 processor from version 5 spectral Level 1 data. The time period covered corresponds to the reduced spectral resolution period of the MIPAS instrument, i.e. January 2005–April 2012. The comparison with satellite instruments includes all post-2005 satellite limb and occultation sensors having measured the vertical profiles of tropospheric and stratospheric ozone: ACE-FTS, GOMOS, HALOE, HIRDLS, MLS, OSIRIS, POAM, SAGE II, SCIAMACHY, SMILES, and SMR. In addition, balloon-borne MkIV solar occultation measurements and groundbased Umkehr measurements have been included, as well as two nadir sensors: IASI and SBUV. For each reference dataset, bias determination and precision assessment are performed. Better agreement with reference instruments than for the previous data version, V5R_O3_220 (Laeng et al., 2013, is found: the known high bias around the ozone vmr peak is significantly reduced and the vertical resolution at 35 km has been improved. The agreement with limb and solar occultation reference instruments that have a known small bias vs. ozone sondes is within 7% in the lower and middle stratosphere and 5% in the upper troposphere. Around the ozone vmr peak, the agreement with most of satellite reference instruments is within 5%; this bias is as low as 3% for ACE-FTS, MLS, OSIRIS, POAM and SBUV.

  13. 49 CFR 173.224 - Packaging and control and emergency temperatures for self-reactive materials.

    Science.gov (United States)

    2010-10-01

    ... Self-reactive liquid, sample 3223 OP2 3 Self-reactive liquid, sample, temperature control 3233 OP2 3 Self-reactive solid, sample 3224 OP2 3 Self-reactive solid, sample, temperature control 3234 OP2 3... 49 Transportation 2 2010-10-01 2010-10-01 false Packaging and control and emergency...

  14. Validation of MIPAS IMK/IAA V5R_O3_224 ozone profiles

    Directory of Open Access Journals (Sweden)

    A. Laeng

    2014-11-01

    Full Text Available We present the results of an extensive validation program of the most recent version of ozone vertical profiles retrieved with the IMK/IAA (Institute for Meteorology and Climate Research/Instituto de Astrofísica de Andalucía MIPAS (Michelson Interferometer for Passive Atmospheric Sounding research level 2 processor from version 5 spectral level 1 data. The time period covered corresponds to the reduced spectral resolution period of the MIPAS instrument, i.e., January 2005–April 2012. The comparison with satellite instruments includes all post-2005 satellite limb and occultation sensors that have measured the vertical profiles of tropospheric and stratospheric ozone: ACE-FTS, GOMOS, HALOE, HIRDLS, MLS, OSIRIS, POAM, SAGE II, SCIAMACHY, SMILES, and SMR. In addition, balloon-borne MkIV solar occultation measurements and ground-based Umkehr measurements have been included, as well as two nadir sensors: IASI and SBUV. For each reference data set, bias determination and precision assessment are performed. Better agreement with reference instruments than for the previous data version, V5R_O3_220 (Laeng et al., 2014, is found: the known high bias around the ozone vmr (volume mixing ratio peak is significantly reduced and the vertical resolution at 35 km has been improved. The agreement with limb and solar occultation reference instruments that have a known small bias vs. ozonesondes is within 7% in the lower and middle stratosphere and 5% in the upper troposphere. Around the ozone vmr peak, the agreement with most of the satellite reference instruments is within 5%; this bias is as low as 3% for ACE-FTS, MLS, OSIRIS, POAM and SBUV.

  15. Aleksandr Gol’ts, Armiia Rossii: 11 poteriannykh let, Moscow: Zakharov, 2004, 224 pp.

    Directory of Open Access Journals (Sweden)

    Richard F. Staar

    2004-07-01

    Full Text Available Specialist of military questions, Aleksandr Gol’ts worked for Red Star (Krasnaia Zvezda, the newspaper of the Russian Ministry of Defense, before joining various prestigious magazines such as Itogi. He is considered one of the most prominent journalist on military matters in Russia today. His book, “The Russian Army : 11 lost years”, is dedicated to military reforms in post-Soviet Russia. With his extensive knowledge of institutional realities of the military establishment, Gol’ts provides a...

  16. 25 CFR 224.30 - What definitions apply to this part?

    Science.gov (United States)

    2010-04-01

    ..., oil, uranium, coal, nuclear, wind, solar, geothermal, biomass, and hydrologic resources. Imminent... RESOURCE AGREEMENTS UNDER THE INDIAN TRIBAL ENERGY DEVELOPMENT AND SELF DETERMINATION ACT General... any activity related to locating, producing, transporting, or marketing energy resources on...

  17. SU-E-J-224: Multimodality Segmentation of Head and Neck Tumors

    International Nuclear Information System (INIS)

    Purpose: Develop an algorithm that is able to automatically segment tumor volume in Head and Neck cancer by integrating information from CT, PET and MR imaging simultaneously. Methods: Twenty three patients that were recruited under an adaptive radiotherapy protocol had MR, CT and PET/CT scans within 2 months prior to start of radiotherapy. The patients had unresectable disease and were treated either with chemoradiotherapy or radiation therapy alone. Using the Velocity software, the PET/CT and MR (T1 weighted+contrast) scans were registered to the planning CT using deformable and rigid registration respectively. The PET and MR images were then resampled according to the registration to match the planning CT. The resampled images, together with the planning CT, were fed into a multi-channel segmentation algorithm, which is based on Gaussian mixture models and solved with the expectation-maximization algorithm and Markov random fields. A rectangular region of interest (ROI) was manually placed to identify the tumor area and facilitate the segmentation process. The auto-segmented tumor contours were compared with the gross tumor volume (GTV) manually defined by the physician. The volume difference and Dice similarity coefficient (DSC) between the manual and autosegmented GTV contours were calculated as the quantitative evaluation metrics. Results: The multimodality segmentation algorithm was applied to all 23 patients. The volumes of the auto-segmented GTV ranged from 18.4cc to 32.8cc. The average (range) volume difference between the manual and auto-segmented GTV was −42% (−32.8%–63.8%). The average DSC value was 0.62, ranging from 0.39 to 0.78. Conclusion: An algorithm for the automated definition of tumor volume using multiple imaging modalities simultaneously was successfully developed and implemented for Head and Neck cancer. This development along with more accurate registration algorithms can aid physicians in the efforts to interpret the multitude of imaging information available in radiotherapy today. This project was supported by a grant by Varian Medical Systems

  18. 22 CFR 224.40 - Stays ordered by the Department of Justice.

    Science.gov (United States)

    2010-04-01

    ... related to such claim or statement, the A.I.D. Administrator shall stay the process immediately. The A.I.D. Administrator may order the process resumed only upon receipt of the written authorization of the Attorney.... Administrator a written finding that continuation of the administrative process described in this part...

  19. Practical Pseudo-collisions for Hash Functions ARIRANG-224/384

    DEFF Research Database (Denmark)

    Guo, Jian; Matusiewicz, Krystian; Knudsen, Lars Ramkilde;

    2009-01-01

    In this paper we analyse the security of the SHA-3 candidate ARIRANG. We show that bitwise complementation of whole registers turns out to be very useful for constructing high-probability differential characteristics in the function. We use this approach to find near-collisions with Hamming weigh...

  20. 两种稀土产品中放射性核素分析研究%ANALYSIS OF RADIONUCLIDES IN TWO RARE EARTH PRODUCTS

    Institute of Scientific and Technical Information of China (English)

    周程; 孙恋君

    2009-01-01

    利用高纯锗γ谱仪对两个稀土产品氯化镧和氯化钇的样品进行能谱分析,研究经湿法冶炼工艺后的稀土产品中放射性核素的活度变化.结果表明,样品中存在天然放射性钍系和锕-铀系的核素,以及天然放射性核素~(138)La和~(176)Lu,但两个样品中所含的放射性核素不相同.氯化镧产品中锕-铀系和钍系核素放射性未达平衡,其主要子体~(224)Ra和~(227)Th的含量随时间发生明显变化,约60天达到平衡;而氯化钇产品没有这种现象.%This paper describes a study on raidoactivity change of rare-earth products after hydrometallurgy technology,using HPGe gamma spectrometer to analyze two rare earth products (LaCl_3 and YCl_3).The results show that in the two samples exist natural radionuclides of thorium series and actinium-uranium series as well as other natural radionuclides 138 La and 176 Lu.In the sample of lanthanum chloride the radioactivity of actinium-uranium series and thorium series has not reached balance,the contents of their main progenies ~(226)Ra and ~(227)Th obviously changes with the time,reaching balance 60 days later,while YCl_3 keeps stability.

  1. Study on laser atomic spectroscopy

    International Nuclear Information System (INIS)

    Laser atomic spectroscopic study on actinium element has been performed in many areas of spectroscopy. The study on characteristic of atomic vapor has been proceeded for copper atom and the spatial density distribution of copper vapor is measured. This experimental data has been compared with the theoretically calculated data. In spectroscopic experiment, the first and second excited states for actinium element are identified and the most efficient ionization scheme for actinium element is identified. In addition, the corrosion problem for filament material due to the heating of the actinium element has been studied. (Author)

  2. Radium-228 determination of natural waters via concentration on manganese dioxide and separation using Diphonix ion exchange resin.

    Science.gov (United States)

    Nour, S; El-Sharkawy, A; Burnett, W C; Horwitz, E P

    2004-12-01

    The objective of this work was to establish a new procedure for 228Ra determination of natural waters via preconcentration of radium on MnO2 and separation of its daughter, 228Ac, using Diphonix ion exchange resin. Following removal of potential interferences via passage through an initial Diphonix Resin column, the first daughter of 228Ra, 228Ac, is isolated by chromatographic separation via a second Diphonix column. A holding time of > 30 h for 228Ac ingrowth in between the two column separations ensures secular equilibrium. Barium-133 is used as a yield tracer. Actinium-228 is eluted from the second Diphonix Resin with 5 ml 1M 1-Hydroxyethane-1,1-diphosphonic acid (HEDPA) and quantified by addition of scintillation cocktail and LSC counting. Radium (and 133Ba) from the load and rinse solutions from the 2nd Diphonix column may be prepared for alpha spectrometry (for determination of 223Ra, 224Ra, and 226Ra) by BaSO4 microprecipitation and filtration. Decontamination tests indicate that U, Th, and Ra series nuclides do not interfere with these measurements, although high contents of 90Sr (90Y) require additional treatment for accurate measurement of 228Ra. Addition of stable Sr as a "hold back" carrier during the initial MnO2 preconcentration step was shown to remove most 90Sr interference.

  3. A Critical Review of Alpha Radionuclide Therapy-How to Deal with Recoiling Daughters?

    Science.gov (United States)

    de Kruijff, Robin M; Wolterbeek, Hubert T; Denkova, Antonia G

    2015-01-01

    This review presents an overview of the successes and challenges currently faced in alpha radionuclide therapy. Alpha particles have an advantage in killing tumour cells as compared to beta or gamma radiation due to their short penetration depth and high linear energy transfer (LET). Touching briefly on the clinical successes of radionuclides emitting only one alpha particle, the main focus of this article lies on those alpha-emitting radionuclides with multiple alpha-emitting daughters in their decay chain. While having the advantage of longer half-lives, the recoiled daughters of radionuclides like 224Ra (radium), 223Ra, and 225Ac (actinium) can do significant damage to healthy tissue when not retained at the tumour site. Three different approaches to deal with this problem are discussed: encapsulation in a nano-carrier, fast uptake of the alpha emitting radionuclides in tumour cells, and local administration. Each approach has been shown to have its advantages and disadvantages, but when larger activities need to be used clinically, nano-carriers appear to be the most promising solution for reducing toxic effects, provided there is no accumulation in healthy tissue. PMID:26066613

  4. A Critical Review of Alpha Radionuclide Therapy—How to Deal with Recoiling Daughters?

    Science.gov (United States)

    de Kruijff, Robin M.; Wolterbeek, Hubert T.; Denkova, Antonia G.

    2015-01-01

    This review presents an overview of the successes and challenges currently faced in alpha radionuclide therapy. Alpha particles have an advantage in killing tumour cells as compared to beta or gamma radiation due to their short penetration depth and high linear energy transfer (LET). Touching briefly on the clinical successes of radionuclides emitting only one alpha particle, the main focus of this article lies on those alpha-emitting radionuclides with multiple alpha-emitting daughters in their decay chain. While having the advantage of longer half-lives, the recoiled daughters of radionuclides like 224Ra (radium), 223Ra, and 225Ac (actinium) can do significant damage to healthy tissue when not retained at the tumour site. Three different approaches to deal with this problem are discussed: encapsulation in a nano-carrier, fast uptake of the alpha emitting radionuclides in tumour cells, and local administration. Each approach has been shown to have its advantages and disadvantages, but when larger activities need to be used clinically, nano-carriers appear to be the most promising solution for reducing toxic effects, provided there is no accumulation in healthy tissue. PMID:26066613

  5. A Critical Review of Alpha Radionuclide Therapy—How to Deal with Recoiling Daughters?

    Directory of Open Access Journals (Sweden)

    Robin M. de Kruijff

    2015-06-01

    Full Text Available This review presents an overview of the successes and challenges currently faced in alpha radionuclide therapy. Alpha particles have an advantage in killing tumour cells as compared to beta or gamma radiation due to their short penetration depth and high linear energy transfer (LET. Touching briefly on the clinical successes of radionuclides emitting only one alpha particle, the main focus of this article lies on those alpha-emitting radionuclides with multiple alpha-emitting daughters in their decay chain. While having the advantage of longer half-lives, the recoiled daughters of radionuclides like 224Ra (radium, 223Ra, and 225Ac (actinium can do significant damage to healthy tissue when not retained at the tumour site. Three different approaches to deal with this problem are discussed: encapsulation in a nano-carrier, fast uptake of the alpha emitting radionuclides in tumour cells, and local administration. Each approach has been shown to have its advantages and disadvantages, but when larger activities need to be used clinically, nano-carriers appear to be the most promising solution for reducing toxic effects, provided there is no accumulation in healthy tissue.

  6. FA224梳棉机出条速度对生条结杂短绒的影响%The Infulunce of FA224 Card Delivery Speed to Tangly Short Floss

    Institute of Scientific and Technical Information of China (English)

    何远方

    2010-01-01

    为了了解出条速度对生条结杂短绒的影响,在一定的工艺设备条件下,纺制了不同的出条速度的生条,通过对这些生条的测试可知:出条速度对生条质量影响明显,出条速度提高后,生条棉结、杂质有增加的趋势,生条中短绒数量也有增大的趋势,生条质量恶化.

  7. 低温等离子射频消融术治疗下咽及喉部病变224例分析%Observation of coblation techinical in treating hypopharynx and larynx diseases (224 cases report)

    Institute of Scientific and Technical Information of China (English)

    罗伟; 吴麟; 陈振宇; 张佳; 郝虹; 王干; 王佩杰

    2016-01-01

    目的:探讨等离子射频消融术治疗下咽及喉部病变的临床应用价值,提高临床疗效。方法回顾性分析2006年4月至2013年4月我科收治的178例下咽病变及46喉部病变患者应用低温等离子射频消融手术的手术方式、手术疗效及术后并发症,探讨低温等离子技术在下咽及喉部病变中的临床应用价值。结果所有手术一次性切除病变完全,术后拔管顺利,无喉梗阻发生,术后恢复良好。下咽组临床治愈169例(94.9%),显效9例(5.1%),总有效率100%,平均住院时间6.8天,所有病例随访1年以上无复发;喉组临床治愈40例(87%),有效4例(8.7%),复发2例(4.3%),2例复发为喉乳头状瘤患者,二次手术后随访1年无复发。平均住院时间7.2天。总有效率95.6%。结论低温等离子射频消融手术创伤小,手术安全性较高、疗效好,住院时间短,是治疗下咽及喉部病变的良好选择。%Objective To explore the clinical valuee of coblation in the treatment of hypopharynx and larynx disease. Methods 178 cases suffered hypopharynx lesion and 46 suffered larynx disease underwent surgical treatment by coblation from April 2006 to April 2013. The operation method, operation effectiveness and postoperation complication were analyzed retrospectively. Results All patients had the total pathological tissue removed without postoperation laryngeal obstruction. Among hypopharynx disease patients, 169 cases were cured and 9 cases had significant therapeutic effect, with a total effective rate of 100%. The mean hospital stay was 6.8 days. In larynx disease patients, 40 were cured and 9 cases had significant therapeutic effect, with a total effective rate of 96.6%. The mean hospital stay was 7.2 days. 2 cased suffered laryngeal papilloma recurrented had second coblation operation and cured in one-year followup. Conclusion Coblation is a safe , effective and minimally invasive way . This operation technical not only shorten the time in hospital but also reduce the cost. It is a valuable selcetive in the treatment of hypopharynx and larynx precancerous lesions.

  8. 224例分化型甲状腺癌放射性碘治疗分析%Experience of 224 patients with differentiated thyroid carcinoma by radioiodine therapy

    Institute of Scientific and Technical Information of China (English)

    郭一玲; 陈佐伟; 张英男; 冯程; 辛镇祓

    2011-01-01

    目的:对在我科8年来治疗的分化型甲状腺癌(DTC)患者进行回顾性分析,了解DTC发病规律,并证明131碘治疗DTC的疗效.方法:2002至2010年确诊为DTC并有颈部淋巴结转移的患者,进行甲状腺近全切除,并进行颈部淋巴结清扫,术后131碘治疗.131碘治疗后,每半年随访一次.随访指标:颈部超声检查;血清TSH、FT4、FT3;血清Tg、TgAb检查;全身放射性碘扫描;胸部CT或MRI.疗效判定:当血清Tg、TgAb阴性,颈部超声未见肿大淋巴结,全身放射性碘扫描未见放射性浓聚时,为DTC治愈.当上述指标为阳性时,则进行再次131碘治疗.用SPSS软件进行统计学处理.结果:DTC患者数逐年明显增加;乳头癌与滤泡癌的比例约为12(207):1(17),女性患者远多于男性,男:女患者患病比例约为1(57):3(167);DTC在20-55岁之间为高发年龄段,峰值在25-35岁之间;131碘治疗对DTC治愈率约达90%,近10%的顽固性DTC患者多次131碘治疗效果欠佳.结论:分化型甲状腺癌患病率有明显增加趋势,25-35岁为高发年龄,女性多于男性,早期诊断及早期治疗是关键.手术切除甲状腺后进行131碘治疗对DTC治愈率达90%.近10%的患者131碘治疗效果欠佳,需寻求更好的治疗方法.%Objective: To study the incidence of differentiated thyroid carcinoma ( DTC ) and the outcome of 131 Iodine therapy for DTC, we summarized retrospectively data of patients with DTC who were managed by 131 Iodine therapy in our department in past 8 years. Methods :Patients with DTC and neck lymph nodes metastasis were diagnosed and near - total thyroidectomy were performed, and neck metastatic lymph nodes were excised. After operation they were treated by radioiodine. Patients were followed up once every half of year after 131 Iodine therapy . To observe the following ired: neck ultrasound test , serum TSH, FT4, FT3 test, serum Tg, TgAb test, radioiodine whole body scan,chest CT or MRI. Assessment of outcome of 131 Iodine therapy: when serum Tg,TgAb test was negative, without detectable metastatic lymph nods in neck ultrasound test, radioiodine whole body scan was negative, it was cure, otherwise 131 Iodine therapy was performed again. Result:DTC rates appear to be rising distinctly year after year, incidence of PDC was higher than that of FTC, the ratio of incidence was 12( 207 ): 1( 17 ) ( PTC :FTC ), incidence of female was higher than male, the ratio was 3 ( 167 ):1( 57 )( female:male ). The incidence of DTC was higher in 20 -55 year. Cured rate of 131 Iodine therapy for DTC was 90%. Conclusion:Thyroid cancer rate appear to be rising distinctly year after year. Incidence of DTC is most high in age of 25 - 35 yeas. Incidence of DTC in female patients is higher than males. Early diagnosis and therapy is most important. Cured rate of DTC is up to 90% , when using 131Iodine therapy after operation consequent TSH suppression therapy. Repeat 131Iodine therapy for near 10% of patients with persistent disease is unsatisfactory.

  9. Bis{2-[(2,4-dimethylphenyliminomethyl]pyridine-κ2N,N′}bis(thiocyanato-κNcadmium

    Directory of Open Access Journals (Sweden)

    Mohammad Malekshahian

    2012-02-01

    Full Text Available The title compound, [Cd(NCS2(C14H14N22], features crystallographic inversion symmetry with the CdII ion located on a centre of inversion. The CdII ion is six-coordinated in a slightly distorted octahedral geometry with the thiocyanate anions in axial positions. The angle between the benzene and pyridine rings is 69.64 (9°. An intermolecular C—H...S hydrogen bond stabilizes the crystal structure.

  10. 2,2-Diethyl 4-methyl 5-(4-nitrophenyl-4-phenylpyrrolidine-2,2,4-tricarboxylate

    Directory of Open Access Journals (Sweden)

    Long He

    2011-10-01

    Full Text Available The title compound, C24H26N2O8, was synthesized by the cycloaddition reaction of methyl 2-phenylacrylate, diethyl 2-aminomalonate and 4-nitrobenzaldehyde. The pyrrolidine ring exhibits an envelope conformation. The two benzene rings are located on opposite sides of the pyrrolidine ring and subtend a dihedral angle of 59.16 (14°. The crystal packing is stabilized by N—H...O and weak C—H...O hydrogen bonding.

  11. Radon fixation for determination of {sup 224}Ra, {sup 226}Ra and {sup 228}Ra via gamma-ray spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Herranz, M. [Departamento Ingenieria Nuclear y Mecanica de Fluidos, E. S. Ingenieros de Bilbao - Universidad del Pais Vasco (UPV/EHU), Alda. Urquijo s/n, 48013 Bilbao (Spain)]. E-mail: inphesom@bi.ehu.es; Idoeta, R. [Departamento Ingenieria Nuclear y Mecanica de Fluidos, E. S. Ingenieros de Bilbao - Universidad del Pais Vasco (UPV/EHU), Alda. Urquijo s/n, 48013 Bilbao (Spain); Abelairas, A. [Departamento Ingenieria Nuclear y Mecanica de Fluidos, E. S. Ingenieros de Bilbao - Universidad del Pais Vasco (UPV/EHU), Alda. Urquijo s/n, 48013 Bilbao (Spain); Legarda, F. [Departamento Ingenieria Nuclear y Mecanica de Fluidos, E. S. Ingenieros de Bilbao - Universidad del Pais Vasco (UPV/EHU), Alda. Urquijo s/n, 48013 Bilbao (Spain)

    2006-04-15

    The aim of this work is the improvement of the procedure for the determination of radium isotopes activities in water, which is done through radiochemical separation and subsequent gamma-ray spectrometry. In addition, radon gas retention is studied using different activated carbon materials. The results of the IAEA Proficiency test: 'Determination of radium and uranium radionuclides in water' of December 2002 [IAEA, 2003. Analytical quality control services: determination of radium and uranium radionuclides in water. Preliminary Report, Seibersdorf] are considered for this work.

  12. A second monoclinic polymorph of 2-[2-(4-methoxyphenylhydrazinylidene]-1,3-diphenylpropane-1,3-dione

    Directory of Open Access Journals (Sweden)

    Carlos Bustos

    2011-07-01

    Full Text Available The title compound, C22H18N2O3 is the second monoclinic polymorph (P21/c of the compound, the first being reported in space group P21 [Bertolasi et al. (1993. J. Chem. Soc. Perkin Trans. 2, pp. 2223–2228]. In the molecular structure of the title compound, the interplanar angle between the benzoyl units is 80.04 (5°, while the corresponding angles between the phenylhydrazinylidene and benzoyl groups are 36.11 (5 and 55.77 (2°. A strong resonance-assisted intramolecular N—H...O hydrogen bond is found. In the crystal, the entire supramolecular structure is constructed by weak intermolecular C—H...O interactions and an inter-ring π–π interaction [centroid–centroid distance = 3.6088 (8 Å].

  13. Rob Hopkins, 2008, The Transition Handbook. From Oil Dependency to Local Resilience, Green books, 224 p.

    Directory of Open Access Journals (Sweden)

    Luc Semal

    2008-07-01

    Full Text Available Le mouvement pour la Transition (ou Transition movement a été initié en 2005 à Totnes (Devon par Rob Hopkins, professeur de permaculture qui avait été sensibilisé au thème du pic du pétrole quelques mois auparavant : à l’époque, il s’agissait seulement d’élaborer une stratégie locale pour que Totnes puisse à l’avenir se passer de pétrole sans en souffrir. Mais d’autres groupes locaux ont rapidement suivi cet exemple, et en mai 2008, le « réseau de la Transition » comptait déjà 50 localités ...

  14. 2-(2,4-Dichlorophenyl-9-phenyl-2,3-dihydrothieno[3,2-b]quinoline

    Directory of Open Access Journals (Sweden)

    K. Balamurugan

    2009-08-01

    Full Text Available In the title compound, C23H15Cl2NS, the quinoline system is almost planar [r.m.s. deviation = 0.013 (2 Å]. The phenyl group is disordered over two positions with site occupancies of 0.55 and 0.45, and is oriented in a nearly perpendicular configuration to the quinoline ring [the dihedral angles between the quinoline ring and the major and minor disordered components of the phenyl ring are 81.8 (2 and 71.6 (2°, respectively]. The dihydrothiene ring adopts an envelope conformation. The dihedral angle between the chlorophenyl ring and the quinoline system is 79.32 (1°. In the crystal weak C—H...π interactions occur.

  15. 2-(2,4-Dichlorophenyl)-9-phenyl-2,3-dihydrothieno[3,2-b]quinoline

    OpenAIRE

    K. Balamurugan; D. Narmadha; Suresh, J.; Perumal, S.; P. L. Nilantha Lakshman

    2009-01-01

    In the title compound, C23H15Cl2NS, the quinoline system is almost planar [r.m.s. deviation = 0.013 (2) Å]. The phenyl group is disordered over two positions with site occupancies of 0.55 and 0.45, and is oriented in a nearly perpendicular configuration to the quinoline ring [the dihedral angles between the quinoline ring and the major and minor disordered components of the phenyl ring are 81.8 (2) and 71.6 (2)°, respectively]. The dih...

  16. 33 CFR 110.224 - San Francisco Bay, San Pablo Bay, Carquinez Strait, Suisun Bay, Sacramento River, San Joaquin...

    Science.gov (United States)

    2010-07-01

    ... area shown on a Government chart. (5) No vessel may moor, anchor, or tie up to any pier, wharf, or... above the upper deck if the vessel has no mast, a red flag at least 16 square feet in area. (6) Each... transfer operations aboard any vessel displaying a red flag in an explosives anchorage. (7) The Captain...

  17. American Recovery and Reinvestment Act (ARRA) Federal Energy Management Program Technical Assistance Project 224 Altus Air Force Base Solar Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Russo, Bryan J.

    2010-09-30

    The principal goal of this project was to evaluate altus Air Force Base for building integrated silicon or thin film module photovoltaic opportunities. This report documents PNNL's efforts and documents study conclusions.

  18. Alpha-emitting isotopes and chromium in a coastal California aquifer

    Science.gov (United States)

    Densmore, Jill N.; Izbicki, John A.; Murtaugh, Joseph M.; Swarzenski, Peter W.; Bullen, Thomas D.

    2014-01-01

    The unadjusted 72-h gross alpha activities in water from two wells completed in marine and alluvial deposits in a coastal southern California aquifer 40 km north of San Diego were 15 and 25 picoCuries per liter (pCi/L). Although activities were below the Maximum Contaminant Level (MCL) of 15 pCi/L, when adjusted for uranium activity; there is concern that new wells in the area may exceed MCLs, or that future regulations may limit water use from the wells. Coupled well-bore flow and depth-dependent water-quality data collected from the wells in 2011 (with analyses for isotopes within the uranium, actinium, and thorium decay-chains) show gross alpha activity in marine deposits is associated with decay of naturally-occurring 238U and its daughter 234U. Radon activities in marine deposits were as high as 2230 pCi/L. In contrast, gross alpha activities in overlying alluvium within the Piedra de Lumbre watershed, eroded from the nearby San Onofre Hills, were associated with decay of 232Th, including its daughter 224Ra. Radon activities in alluvium from Piedra de Lumbre of 450 pCi/L were lower than in marine deposits. Chromium VI concentrations in marine deposits were less than the California MCL of 10 μg/L (effective July 1, 2014) but δ53Cr compositions were near zero and within reported ranges for anthropogenic chromium. Alluvial deposits from the nearby Las Flores watershed, which drains a larger area having diverse geology, has low alpha activities and chromium as a result of geologic and geochemical conditions and may be more promising for future water-supply development.

  19. Comparison of estimated energy intake from 224-hour recalls and a seven-day food record with objective measurements of energy expenditure in children

    DEFF Research Database (Denmark)

    Rothausen, Berit Worm; Matthiessen, Jeppe; Groth, Margit Velsing;

    2012-01-01

    Objective: The objective of the present study was to evaluate energy intake (EI) estimated from two nonconsecutive 24-hour recalls (24-HDRs) and a pre-coded seven-day food record (7-dFR) against objective measurements of energy expenditure (EE) in children. Design: A total of 67 78 year-olds and 64...

  20. Bis{2-[(2,4-dimethyl-phen-yl)imino-meth-yl]pyridine-κN,N'}bis-(thio-cyanato-κN)cadmium.

    Science.gov (United States)

    Malekshahian, Mohammad; Talei Bavil Olyai, Mohamad Reza; Notash, Behrouz

    2012-02-01

    The title compound, [Cd(NCS)(2)(C(14)H(14)N(2))(2)], features crystallographic inversion symmetry with the Cd(II) ion located on a centre of inversion. The Cd(II) ion is six-coordinated in a slightly distorted octa-hedral geometry with the thiocyanate anions in axial positions. The angle between the benzene and pyridine rings is 69.64 (9)°. An inter-molecular C-H⋯S hydrogen bond stabilizes the crystal structure. PMID:22346881

  1. Synthesis, spectroscopic studies and crystal structure of ( E)-2-(2,4-dihydroxybenzylidene)thiosemicarbazone and ( E)-2-[(1 H-indol-3-yl)methylene]thiosemicarbazone

    Science.gov (United States)

    Yıldız, Mustafa; Ünver, Hüseyin; Erdener, Diğdem; Kiraz, Aşkın; İskeleli, Nazan Ocak

    2009-02-01

    Thiosemicarbazone Schiff bases ( 1 and 2) derived from 2,4-dihydroxybenzaldehyde, indoline-3-carbaldehyde and thiosemicarbazone have been synthesized and their structures were elucidated by elemental analysis, FT-IR, 1H NMR, 13C NMR and UV-visible spectroscopic techniques. The structures of compounds 1 and 2 have also been examined cyrstallographically. The title compounds 1 and 2 crystallize in the monoclinic space group C2/ c and triclinic space group P1¯, with unit cell parameters: a = 21.421(1) and 7.233(1), b = 4.131(1) and 11.166(1), c = 24.942(2) and 13.648(1) Å, V = 1856.1(2) and 1019.5(1) Å 3, D x = 1.512 and 1.422 g cm -3 and Z = 8 and 4, respectively.

  2. Analysis of back-propagation and RF pilot-tone based nonlinearity compensation for a 9x224Gb/s POLMUX-16QAM system

    OpenAIRE

    Díaz Souto, Alberto; Napoli, Antonio; Adhikari, Susmita; Maalej, Zied; Lobato Polo, Adriana P.; Kuschnerov, Maxim; Prat Gomà, Josep Joan

    2012-01-01

    We investigate the joint implementation of back-propagation and RF-pilot tone for fiber nonlinear compensation in POLMUX-16QAM and show that the nonlinear tolerance is drastically improved when compared to OFDM system Peer Reviewed

  3. Hyperspectral surface materials map of quadrangle 3670, Jurm-Kishim (223) and Zebak (224) quadrangles, Afghanistan, showing iron-bearing minerals and other materials

    Science.gov (United States)

    King, Trude V.V.; Hoefen, Todd M.; Kokaly, Raymond F.; Livo, Keith E.; Johnson, Michaela R.; Giles, Stuart A.

    2013-01-01

    This map shows the spatial distribution of selected iron-bearing minerals and other materials derived from analysis of airborne HyMap™ imaging spectrometer (hyperspectral) data of Afghanistan collected in late 2007. This map is one in a series of U.S. Geological Survey/Afghanistan Geological Survey quadrangle maps covering Afghanistan. Flown at an altitude of 50,000 feet (15,240 meters (m)), the HyMap™ imaging spectrometer measured reflected sunlight in 128 channels, covering wavelengths between 0.4 and 2.5 μm. The data were georeferenced, atmospherically corrected and converted to apparent surface reflectance, empirically adjusted using ground-based reflectance measurements, and combined into a mosaic with 23-m pixel spacing. Variations in water vapor and dust content of the atmosphere, in solar angle, and in surface elevation complicated correction; therefore, some classification differences may be present between adjacent flight lines. The reflectance spectrum of each pixel of HyMap™ imaging spectrometer data was compared to the reference materials in a spectral library of minerals, vegetation, water, and other materials. Minerals occurring abundantly at the surface and those having unique spectral features were easily detected and discriminated, while minerals having slightly different compositions but similar spectral features were less easily discriminated; thus, some map classes consist of several minerals having similar spectra, such as “Goethite and jarosite.” A designation of “Not classified” was assigned to the pixel when there was no match with reference spectra.

  4. Hyperspectral surface materials map of quadrangle 3670, Jurm-Kishim (223) and Zebak (224) quadrangles, Afghanistan, showing carbonates, phyllosilicates, sulfates, altered minerals, and other materials

    Science.gov (United States)

    Kokaly, Raymond F.; King, Trude V.V.; Hoefen, Todd M.; Livo, Keith E.; Johnson, Michaela R.; Giles, Stuart A.

    2013-01-01

    This map shows the spatial distribution of selected carbonates, phyllosilicates, sulfates, altered minerals, and other materials derived from analysis of airborne HyMap™ imaging spectrometer (hyperspectral) data of Afghanistan collected in late 2007. The map is one in a series of U.S. Geological Survey/Afghanistan Geological Survey quadrangle maps covering Afghanistan. Flown at an altitude of 50,000 feet (15,240 meters (m)), the HyMap™ imaging spectrometer measured reflected sunlight in 128 channels, covering wavelengths between 0.4 and 2.5 μm. The data were georeferenced, atmospherically corrected and converted to apparent surface reflectance, empirically adjusted using ground-based reflectance measurements, and combined into a mosaic with 23-m pixel spacing. Variations in water vapor and dust content of the atmosphere, in solar angle, and in surface elevation complicated correction; therefore, some classification differences may be present between adjacent flight lines. The reflectance spectrum of each pixel of HyMap™ imaging spectrometer data was compared to the reference materials in a spectral library of minerals, vegetation, water, and other materials. Minerals occurring abundantly at the surface and those having unique spectral features were easily detected and discriminated, while minerals having slightly different compositions but similar spectral features were less easily discriminated; thus, some map classes consist of several minerals having similar spectra, such as “Epidote or chlorite.” A designation of “Not classified” was assigned to the pixel when there was no match with reference spectra.

  5. Design, synthesis, biological activities, and 3D-QSAR of new N,N'-diacylhydrazines containing 2-(2,4-dichlorophenoxy)propane moiety.

    Science.gov (United States)

    Liu, Xing-Hai; Pan, Li; Ma, Yi; Weng, Jian-Quan; Tan, Cheng-Xia; Li, Yong-Hong; Shi, Yan-Xia; Li, Bao-Ju; Li, Zheng-Ming; Zhang, Yong-Gang

    2011-10-01

    A series of new N,N'-diacylhydrazine derivatives were synthesized efficiently under microwave irradiation. Their structures were characterized by (1) H NMR, MS, and elemental analysis. Various biological activities of these compounds were tested. Most of them exhibited higher herbicidal activities against dicotyledonous weeds than monocotyledonous weeds. In addition, favorable in vivo fungicidal activities were also found of these compounds against Cladosporium cucumerinum, Corynespora cassiicola, Sclerotinia sclerotiorum(Lib.)de Bary, Erysiphe cichoracearum, and Colletotrichum orbiculare (Berk aLMont) Arx. All compounds displayed excellent plant growth regulatory activities: 100% inhibition was achieved against the radicle growth of cucumber. To further investigate the structure-activity relationship, comparative molecular field analysis was performed on the basis of herbicidal activity data, resulting in a statistically reliable model with good predictive power (r(2) = 0.913, q(2) =0.556). Based on the calculation, five additional novel compounds were designed and synthesized. Satisfyingly, compound 4u displayed excellent herbicidal activity (94.7%) at 1500 g/ha, although it is less active than 2,4-D. Meanwhile, this compound also exhibited good fungicidal activity against C. orbiculare (Berk aLMont) Arx (82.16%). PMID:21816005

  6. Acetalization of carbonyl compounds with 2,2,4-trimethyl-1,3-pentanedio catalyzed by novel carbon based solid acid catalyst

    Institute of Scientific and Technical Information of China (English)

    Ling Liu; Yuechang Zhao; Shan Gan; Xuezheng Liang; Jianguo Yang; Mingyuan He

    2008-01-01

    The synthesis of 2, 4-diisopropyl-5,5-dimethyl-1,3-dioxane through the acetalization of isobutyraldehyde with 2, 2,4-trimethyl-1,3-pentanediol (TMPD) catalyzed by the novel carbon based acid was first carried out. High conversion (≥98%) and specific selectivity were obtained using the novel carbon based acid, which kept high activity after it was reused 5 times.Moreover, the catalyst could be used to catalyze the acetalization and ketalization of different aldehydes and ketones with superior yield. The yield of several products was over 90%. The novel heterogeneous catalyst has the distinct advantages of high activity, strikingly simple workup procedure, non-pollution, and reusability, which will contribute to the success of the green process greatly.

  7. SU-E-J-224: Using UTE and T1 Weighted Spin Echo Pulse Sequences for MR-Only Treatment Planning; Phantom Study

    Energy Technology Data Exchange (ETDEWEB)

    Yu, H; Fatemi, A [Sunnybrook Health Sciences Centre, Toronto, Ontario (Canada); Sahgal, A [University of Toronto, Toronto, ON (Canada)

    2015-06-15

    Purpose: Investigating a new approach in MRI based treatment planning using the combination of (Ultrashort Echo Time) UTE and T1 weighted spin echo pulse sequences to delineate air, bone and water (soft tissues) in generating pseudo CT images comparable with CT. Methods: A gel phantom containing chicken bones, ping pang balls filled with distilled water and air bubbles, was made. It scanned with MRI using UTE and 2D T1W SE pulse sequences with (in plane resolution= 0.53mm, slice thickness= 2 mm) and CT with (in plane resolution= 0.5 mm and slice thickness= 0.75mm) as a ground truth for geometrical accuracy. The UTE and T1W SE images were registered with CT using mutual information registration algorithm provided by Philips Pinnacle treatment planning system. The phantom boundaries were detected using Canny edge detection algorithm for CT, and MR images. The bone, air bubbles and water in ping pong balls were segmented from CT images using threshold 300HU, - 950HU and 0HU, respectively. These tissue inserts were automatically segmented from combined UTE and T1W SE images using edge detection and relative intensity histograms of the phantom. The obtained segmentations of air, bone and water inserts were evaluated with those obtained from CT. Results: Bone and air can be clearly differentiated in UTE images comparable to CT. Combining UTE and T1W SE images successfully segmented the air, bone and water. The maximum segmentation differences from combine MRI images (UTE and T1W SE) and CT are within 1.3 mm, 1.1mm for bone, air, respectively. The geometric distortion of UTE sequence is small less than 1 pixel (0.53 mm) of MR image resolution. Conclusion: Our approach indicates that MRI can be used solely for treatment planning and its quality is comparable with CT.

  8. Prevalence study: main illicit psychoactive susbtances among all drivers involved in fatal road crashes in France. Delivrable 2.2.4

    OpenAIRE

    Amoros, E.; Gadegbeku, B.; THE SAM GROUP; 103-111,

    2010-01-01

    In 1999, in France, before considering change in the drug legislation, the government wished to know more on the effect of illicit drugs on the risk of road crashes. A systematic screening of illicit drug on all drivers involved in fatal crashes, was hence made compulsory. We estimate prevalences of alcohol, cannabis, amphetamines, cocaine, and opiates. We provide them for drivers of all vehicles types, as well as for car drivers only. We also provide estimates of prevalences in the general p...

  9. 25 CFR 224.83 - What must a tribe do after executing a lease or business agreement, or granting a right-of-way?

    Science.gov (United States)

    2010-04-01

    ... DEVELOPMENT AND SELF DETERMINATION ACT Implementation of Tribal Energy Resource Agreements Leases, Business... agreement, or granting a right-of-way? Following the execution of a lease, business agreement, or grant of... 25 Indians 1 2010-04-01 2010-04-01 false What must a tribe do after executing a lease or...

  10. (2RS-2-(2,4-Difluorophenyl-1-[(4-iodobenzyl(methylamino]-3-(1H-1,2,4-triazol-1-ylpropan-2-ol

    Directory of Open Access Journals (Sweden)

    Hui-Ping Xiong

    2012-08-01

    Full Text Available In the title compound (common name: iodiconazole, C19H19F2IN4O, there is an intramolecular O—H...N hydrogen bond and molecules are linked by weak interactions only, namely C—H...N, C—H...O and C—H...F hydrogen bonds, and π-electron ring–π-electron ring interactions between the triazole rings with centroid–centroid distances of 3.725 (3 Å.

  11. VizieR Online Data Catalog: Hi-GAL l=224deg region CO(1-0) data cubes (Olmi+, 2016)

    Science.gov (United States)

    Olmi, L.; Cunningham, M.; Elia, D.; Jones, P.

    2016-08-01

    The files are the Mopra telescope data cubes used to produce the channel maps shown in Appendix A. Intensity units are Ta*[K]. Data cubes are not (baseline) reduced. Noise in the maps is not uniform. Frequency resolution is 33.7kHz. (2 data files).

  12. The bispectrum of the Lyman-alpha forest at z~2-2.4 from a Large sample of UVES QSO Absorption Spectra (LUQAS)

    CERN Document Server

    Viel, M; Heavens, A; Hähnelt, M G; Kim, T S; Springel, V; Hernquist, L

    2004-01-01

    We present a determination of the bispectrum of the flux in the Lyman-alpha forest of QSO absorption spectra obtained from LUQAS which consists of spectra observed with the high resolution Echelle spectrograph UVES. Typical errors on the observed bispectrum as obtained from a jack-knife estimator are ~ 50%. For wavenumbers in the range 0.03 s/km 2.

  13. 9 CFR 381.224 - Designation of States under section 11 of the Act; application of sections of the Act and the...

    Science.gov (United States)

    2010-01-01

    ... and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION... or for commerce) in (1) the business of slaughtering any poultry or processing, freezing, packaging, or labeling any poultry carcasses, or parts or products thereof, for use as human food or animal...

  14. Submarine groundwater discharge revealed by radium isotopes (Ra-223 and Ra-224 near a paleochannel on the Southern Brazilian continental shelf

    Directory of Open Access Journals (Sweden)

    Karina Kammer Attisano

    2013-09-01

    Full Text Available Submarine Groundwater Discharge (SGD has been recognized as an important component of the ocean-continent interface. The few previous studies in Brazil have focused on nearshore areas. This paper explores SGD on the Southern Brazilian Continental Shelf using multiple lines of evidence that include radium isotopes, dissolved nutrients, and water mass observations. The results indicated that SGD may be occurring on the Continental Shelf in the Albardão region, near a paleochannel located 50 km offshore. This paleochannel may thus be a preferential pathway for the delivery of nutrient- and metal-enriched groundwater and porewater into continental shelf waters.

  15. Alpha-emitting isotopes and chromium in a coastal California aquifer

    International Nuclear Information System (INIS)

    Highlights: • Alluvium in Piedra de Lumbre basin higher radionuclides likely from natural Th. • Natural uranium decay-chain isotopes, including Ra, present in marine deposits. • Marine deposits also contain low concentrations of chromium. • Radionuclides and chromium concentrations lower in alluvium in the Las Flores basin. - Abstract: The unadjusted 72-h gross alpha activities in water from two wells completed in marine and alluvial deposits in a coastal southern California aquifer 40 km north of San Diego were 15 and 25 picoCuries per liter (pCi/L). Although activities were below the Maximum Contaminant Level (MCL) of 15 pCi/L, when adjusted for uranium activity; there is concern that new wells in the area may exceed MCLs, or that future regulations may limit water use from the wells. Coupled well-bore flow and depth-dependent water-quality data collected from the wells in 2011 (with analyses for isotopes within the uranium, actinium, and thorium decay-chains) show gross alpha activity in marine deposits is associated with decay of naturally-occurring 238U and its daughter 234U. Radon activities in marine deposits were as high as 2230 pCi/L. In contrast, gross alpha activities in overlying alluvium within the Piedra de Lumbre watershed, eroded from the nearby San Onofre Hills, were associated with decay of 232Th, including its daughter 224Ra. Radon activities in alluvium from Piedra de Lumbre of 450 pCi/L were lower than in marine deposits. Chromium VI concentrations in marine deposits were less than the California MCL of 10 μg/L (effective July 1, 2014) but δ53Cr compositions were near zero and within reported ranges for anthropogenic chromium. Alluvial deposits from the nearby Las Flores watershed, which drains a larger area having diverse geology, has low alpha activities and chromium as a result of geologic and geochemical conditions and may be more promising for future water-supply development

  16. Pertactin-negative Bordetella pertussis strains in Canada: characterization of a dozen isolates based on a survey of 224 samples collected in different parts of the country over the last 20 years

    Directory of Open Access Journals (Sweden)

    Raymond S.W. Tsang

    2014-11-01

    Conclusions: As reported elsewhere, pertactin-negative B. pertussis has emerged in Canada in recent years, notably in 2012. This coincided with an increase in pertussis activity in Canada. A further systematic study with a larger geographical representative sample is required to determine how these vaccine-negative strains may contribute to the overall changing epidemiology of pertussis in Canada.

  17. Synthesis, coordination and biological aspects of organotin(IV) derivatives of 4-[(2,4-dinitrophenyl)amino)]-4-oxo-2-butenoic acid and 2-{[(2,4-dinitrophenyl)amino]carbonyl}benzoic acid

    OpenAIRE

    KHADIJA SHAHID; SAIRA SHAHZADI; SAQIB ALI

    2009-01-01

    New series of organotin(IV) complexes of aniline derivatives, R2SnL2 and R3SnL [where R = Me, n-Bu, Ph, n-Oct] have been synthesized by the reaction of HL1 and HL2 with respective organotin halides or oxides. Experimental details for the preparation and characterization (including elemental analysis, IR and multinuclear NMR (1H-, 13C- and 119Sn-) spectra in CDCl3 and EI mass spectra of both series are provided. The binding sites of the ligands were identified by means of FTIR spectroscopic me...

  18. Synthesis, coordination and biological aspects of organotin(IV derivatives of 4-[(2,4-dinitrophenylamino]-4-oxo-2-butenoic acid and 2-{[(2,4-dinitrophenylamino]carbonyl}benzoic acid

    Directory of Open Access Journals (Sweden)

    KHADIJA SHAHID

    2009-02-01

    Full Text Available New series of organotin(IV complexes of aniline derivatives, R2SnL2 and R3SnL [where R = Me, n-Bu, Ph, n-Oct] have been synthesized by the reaction of HL1 and HL2 with respective organotin halides or oxides. Experimental details for the preparation and characterization (including elemental analysis, IR and multinuclear NMR (1H-, 13C- and 119Sn- spectra in CDCl3 and EI mass spectra of both series are provided. The binding sites of the ligands were identified by means of FTIR spectroscopic measurements. It was found that in all cases the organotin(IV moiety reacts with the oxygen of COO– group to form new complexes. In the diorganotin complexes, the COO– group is coordinated to the organotin(IV centres in a bidentate manner in the solid state. The 119Sn NMR data and the nJ(13C‑119/117Sn coupling constant support the tetrahedral coordination geometry of the organotin complexes in non-coordinating solvents. Biological activities (antibacterial, antifungal, cytotoxicity, antileishmanial and insecticidal of these compounds are also reported.

  19. Andrea Ostrov, Espacios de ficción. Espacio, poder y escritura en la literatura latinoamericana : Villa María (Córdoba), EDUVIM, 2014, 224 páginas

    OpenAIRE

    Rodríguez Pérsico, Adriana

    2015-01-01

    Para empezar, una serie de coincidencias felices. El título del libro de Andrea Ostrov, Espacios de ficción. Espacio, poder y escritura en la literatura latinoamericana, encastra de forma casi perfecta en el título de la colección que dirige Roxana Patiño, Zona crítica. Se trata, entonces, de espacios y de zonas, de ficción y de crítica. De pensar espacios para la reflexión crítica que derivan en preguntas ineludibles: ¿qué espacio hay hoy para la crítica?, ¿qué zonas ficcionales o reales som...

  20. Hallucinogen-like effects of 2-([2-(4-cyano-2,5-dimethoxyphenyl) ethylamino]methyl)phenol (25CN-NBOH), a novel N-benzylphenethylamine with 100-fold selectivity for 5-HT2A receptors, in mice

    DEFF Research Database (Denmark)

    Fantegrossi, William E; Gray, Bradley W; Bailey, Jessica M;

    2015-01-01

    characterized. OBJECTIVE: 25CN-NBOH was compared to the traditional phenethylamine hallucinogen R(-)-2,5-dimethoxy-4-iodoamphetamine (DOI) using mouse models of drug-elicited head twitch behavior and drug discrimination. METHODS: Drug-elicited head twitches were quantified for 10 min following administration...... of various doses of either DOI or 25CN-NBOH, with and without pretreatments of 0.01 mg/kg 5-HT2A antagonist M100907 or 3.0 mg/kg 5-HT2C antagonist RS102221. The capacity of 25CN-NBOH to attenuate DOI-elicited head twitch was also investigated. Mice were trained to discriminate DOI or M100907 from saline......, and 25CN-NBOH was tested for generalization. RESULTS: 25CN-NBOH induced a head twitch response in the mouse that was lower in magnitude than that of DOI, blocked by M100907, but not altered by RS102221. DOI-elicited head twitch was dose-dependently attenuated by 25CN-NBOH pretreatment. 25CN-NBOH produced...

  1. Keystone Symposia "ncRNAs in Development and Cancer", Vancouver, Canada: Increased release of exosomes and export of invasion-modulating miRNAs miR921, -23b, -and -224 from metastatic urothelial carcinoma cells

    DEFF Research Database (Denmark)

    Ostenfeld, Marie Stampe; Jeppesen, Dennis Kjølhede; Laurberg, Jens Reumert;

    2013-01-01

    Cancer cells secrete soluble factors and various extracellular vesicles, including exosomes, into their tissue microenvironment. The secretion of exosomes is speculated to facilitate local invasion and increase the propensity of tumors to form distant metastases. Here we present a characterization...... of exosome vesicles from isogenic urothelial carcinoma cell lines, with different metastatic propensity by western blotting, electron microscopy, nanoparticle tracking analysis, dynamic light scattering, and profiling of 671 miRNAs by qRT-PCR. An increase in the number of multivesicular bodies and exosomes...... was observed for metastatic FL3 cells compared to isogenic non-metastatic T24 cells. The release was significantly inhibited by knockdown of Rab27b and pharmacological inhibition of nsmase2 by GW4869. miRNA profiling was conducted on parental cells and their secreted exosomes. Here, selective export of miR921...

  2. Atenção farmacêutica para pacientes hipertensos – nova metodologia e a importância dessa prática no acompanhamento domiciliar - 10.5020/18061230.2008.p224

    OpenAIRE

    Valdomiro Vagner de Souza; Ana Lúcia Francisco Bertoncin

    2012-01-01

    Objetivo: Avaliar e ampliar o conhecimento dos pacientes sobre a hipertensão arterial, buscando orientá-los e estimulá-los ao uso correto dos medicamentos e à adesão a estilo de vida adequado, salientando a importância da atenção farmacêutica domiciliar no tratamento da doença. Métodos: Estudo prospectivo, experimental e longitudinal, realizado com 10 pacientes hipertensos de uma farmácia municipal, selecionados aleatoriamente. Dados sobre os hábitos de vida, medicamentos uti izados e resulta...

  3. (2RS)-2-(2,4-Difluorophenyl)-1-[(4-iodobenzyl)(methyl)amino]-3-(1H-1,2,4-triazol-1-yl)propan-2-ol

    OpenAIRE

    Hui-Ping Xiong; Shou-Hong Gao; Chun-Tong Li; Zhi-Jun Wu

    2012-01-01

    In the title compound (common name: iodiconazole), C19H19F2IN4O, there is an intramolecular O—H...N hydrogen bond and molecules are linked by weak interactions only, namely C—H...N, C—H...O and C—H...F hydrogen bonds, and π-electron ring–π-electron ring interactions between the triazole rings with centroid–centroid distances of 3.725 (3) Å.

  4. Book Review: The future of spacetime. Stephen William Hawking (ed.); Kip S. Thorne, Igor Novikov, Timothy Ferris, Alan Lightman, and Richard Price, W.W. Norton & Company, 2002, 224 pp., US 25.95, ISBN 0393020223

    Science.gov (United States)

    Smeenk, Chris

    The study of Einstein's theory of general relativity experienced a renaissance beginning in the early 1960s. Prior to this resurgence of interest, general relativity was isolated from mainstream physics-admired for its elegance, perhaps, but only from a distance. The generation of students who risked their careers by entering this neglected field has now reached the age of festschrifts. In June of 2000, Caltech hosted "Kipfest," a conference in honor of Kip Thorne's 60th birthday. Thorne started graduate school at Princeton in 1962 and began research in general relativity under John Wheeler's guidance in the heady early days of the renaissance. Since then, he has played a prominent role in general relativity: as co-author of the influential textbook Gravitation, as a leader in research regarding astrophysical applications of Einstein's theory, and as a co-founder and chief advocate for the Laser Interferometer Gravitational Wave Observatory (LIGO), to mention a few aspects of his far-reaching work. "Kipfest" included 14 speakers discussing fields to which Thorne has contributed. But the conference also reflected Thorne's long-standing commitment to communicating science to a general audience: Igor Novikov, Stephen Hawking, Timothy Ferris, and Alan Lightman gave popular talks at "Kipfest," with Thorne himself tricked into delivering a fifth. The Future of Spacetime gathers adaptations of these five lectures, along with a lengthy introductory essay by Richard Price.

  5. Carlos Raúl Hernández, Agonía de la democracia. ¿A dónde va Venezuela con la "revolución bolivariana”, Caracas, Panapo, 2001, 224 pp.

    OpenAIRE

    Langue, Frédérique

    2005-01-01

    Desde el mes de abril de 2002 y el intento de golpe de Estado, la llamada revolución bolivariana se ha vendido enfrentando con unos cuestionamientos más radicales. Este libro, publicado antes de que se multiplicaran las protestas y otras formas de "desobediencia civil, permite abordar este proceso desde la perspectiva de las ideologías y de las creencias, vistas por un sociólogo que desde hace varios años, ha centrado su reflexión en torno a los temas de la democracia, de la libertad y del ca...

  6. Visual Symmetry. By Magdolna Hargittai and István Hargittai, World Scientific Publishing, 2009; 224 pages. Price: US$ 48 / £ 36 ISBN 978-981-283-531-4

    OpenAIRE

    Shu-Kun Lin

    2009-01-01

    Symmetry is as simple or as complicated as we are ready to absorb it in everything around us. From flowers to bridges, buildings, coke machines, and snowflakes; from molecules to walnuts, fences, pine cones, and sunflowers; from music to children's drawings; from hubcaps to bank logos, propellers, wallpaper decorations, and pavements, we recognize it if we walk around with open eyes and an open mind. This book provides aesthetic pleasure and covert education, immersing the reader in both the ...

  7. Visual Symmetry. By Magdolna Hargittai and István Hargittai, World Scientific Publishing, 2009; 224 pages. Price: US$ 48 / £ 36 ISBN 978-981-283-531-4

    Directory of Open Access Journals (Sweden)

    Shu-Kun Lin

    2009-10-01

    Full Text Available Symmetry is as simple or as complicated as we are ready to absorb it in everything around us. From flowers to bridges, buildings, coke machines, and snowflakes; from molecules to walnuts, fences, pine cones, and sunflowers; from music to children's drawings; from hubcaps to bank logos, propellers, wallpaper decorations, and pavements, we recognize it if we walk around with open eyes and an open mind. This book provides aesthetic pleasure and covert education, immersing the reader in both the familiar and the unknown and leading always to unexpected discoveries.

  8. Dussel, Inés y Caruso, Marcelo. La invención del aula. Una genealogía de las formas de enseñar : Santillana, Buenos Aires, 1999, 224 páginas

    OpenAIRE

    Morras, Valeria

    2006-01-01

    Inés Dussel y Marcelo Caruso al asumir una mirada genealógica, realizan un recorrido histórico, sin pretensiones de neutralidad, sobre la configuración del aula de clase como espacio educativo privilegiado y las prácticas pedagógicas que en ella se llevan a cabo. La intención es desnaturalizar el aula. Se proponen “interrogar lo obvio”, “saber por qué el aula es como es”, por qué se realizan dentro de ella determinados discursos y prácticas: de dónde surgen, cuáles son sus significados y efec...

  9. VLT/UVES observations of extremely strong intervening damped Lyman-alpha systems: Molecular hydrogen and excited carbon, oxygen and silicon at log N(HI)=22.4

    CERN Document Server

    Noterdaeme, P; Rahmani, H; Petitjean, P; Pâris, I; Ledoux, C; Gupta, N; López, S

    2015-01-01

    We present a detailed analysis of three extremely strong intervening DLAs (log N(HI)>=21.7) observed towards quasars with VLT/UVES. We measure overall metallicities of [Zn/H]~-1.2, -1.3 and -0.7 at respectively zabs=2.34 towards SDSS J2140-0321 (log N(HI) = 22.4+/-0.1), zabs=3.35 towards SDSS J1456+1609 (log N(HI) = 21.7+/-0.1) and zabs=2.25 towards SDSS J0154+1935 (log N(HI) = 21.75+/-0.15). We detect H2 towards J2140-0321 (log N(H2) = 20.13+/-0.07) and J1456+1609 (log N(H2) = 17.10+/-0.09) and argue for a tentative detection towards J0154+1935. Absorption from the excited fine-structure levels of OI, CI and SiII are detected in the system towards J2140-0321, that has the largest HI column density detected so far in an intervening DLA. This is the first detection of OI fine-structure lines in a QSO-DLA, that also provides us a rare possibility to study the chemical abundances of less abundant atoms like Co and Ge. Simple single phase photo-ionisation models fail to reproduce all the observed quantities. Inst...

  10. 10 CFR Appendix E to Part 20 - Nationally Tracked Source Thresholds

    Science.gov (United States)

    2010-01-01

    ... Category 1(TBq) Category 1(Ci) Category 2(TBq) Category 2(Ci) Actinium-227 20 540 0.2 5.4 Americium-241 60... 2 54 Strontium-90 1,000 27,000 10 270 Thorium-228 20 540 0.2 5.4 Thorium-229 20 540 0.2 5.4...

  11. I. The metabolic properties of plutonium and allied materials

    Energy Technology Data Exchange (ETDEWEB)

    Hamilton, J.G.

    1948-05-24

    This report on the metabolic properties of plutonium and related radioactive materials presents experimental information in the following areas: radioautographic studies; tracer studies (with tables of accumulation in tissues) of actinium, radio-zirconium, technetium, radio-rubidium, radio-germanium, beryllium, and cadmium; decontamination and bone metabolism studies; and radio-chemical isolation.

  12. 10 CFR Appendix B to Part 20 - Annual Limits on Intake (ALIs) and Derived Air Concentrations (DACs) of Radionuclides for...

    Science.gov (United States)

    2010-01-01

    .... Actinium Ac 89 Aluminum Al 13 Americium Am 95 Antimony Sb 51 Argon Ar 18 Arsenic As 33 Astatine At 85... Curium Cm 96 Dysprosium Dy 66 Einsteinium Es 99 Erbium Er 68 Europium Eu 63 Fermium Fm 100 Fluorine F...

  13. Investigation for determining the retention properties of rock over the ASSE II mine for dissolved radionuclides

    International Nuclear Information System (INIS)

    For a model consideration of groundwater movement and the associated transport of dissolved substance in deep groundwater, the retention properties of the ASSE II mine for radionuclides dissolved in water were determined. A series of properties of rocks were examined and described for this purpose. Apart from the chemical, mineralogical and petrophysical characteristics of the rocks, the retention was determined by 3 different methods and stated in the form of distribution coefficients for specific elements. A comparison of the results of vibration and diffusion experiments gave good agreement, while the results in through column experiments only reached the same order of magnitude after an expensive determination with the aid of a place concentration distribution. The distribution coefficients for the elements carbon, selenium, strontium, technetium, iodine, caesium, lead, radium, actinium, proto-actinium, uranium, neptunium, plutonium, americium and curium are listed and collected for model rock packages. (orig./HP)

  14. Пинг Ж. Затмение в Африке: нужно ли было убивать Каддафи? – Париж: Издательство «Мишалон», 2014 – 224 с. (Ping J. Eclipse sur l’Afrique: fallait-il tuer Kadhafi? – Paris: Michalon Editeur, 2014 – 224 p.)

    OpenAIRE

    Кривенкова, Ольга Владимировна

    2016-01-01

    Книга Жана Пинга «Затмение в Африке: нужно ли было убивать Каддафи?», опубликованная в Париже в 2014 г., посвящена событиям гражданской войны в Ливии и международной операции/ Бывший министр иностранных дел Габона (1999-2008 гг.), председатель Комиссии Африканского союза (2008-2013 гг.), автор являлся не только свидетелем разжегшегося в Ливии конфликта, но принимал непосредственное участие в попытках мирного урегулирования ливийского кризиса, будучи членом делегации АС, направленной на перего...

  15. LASL experience in decontamination of the environment

    International Nuclear Information System (INIS)

    This discussion represents one part of a major effort in soil decontamination at the Los Alamos site. A contaminated industrial waste line in the Los Alamos townsite was removed, and a plutonium incineration facility, and a filter building contaminated with actinium-227 were dismantled. The former plutonium handling facility has been decontaminated, and canyons and an old firing site contaminated with strontium-90 have been surveyed

  16. Sorption studies of radioelements on geological materials

    OpenAIRE

    Berry, J. A; 油井 三和; 北村 暁

    2007-01-01

    Batch sorption experiments have been carried out to study the sorption of uranium, technetium, curium, neptunium, actinium, protactinium, polonium, americium and plutonium onto bentonite, granodiorite and tuff. Mathematical modelling using the HARPHRQ program and the HATCHES database was carried out to predict the speciation of uranium and technetium in the equilibrated seawater, and neptunium, americium and plutonium in the rock equilibrated water. Review of the literature for thermodynamic ...

  17. Study of the origin of elements of the uranium-235 family observed in excess in the vicinity of the experimental nuclear EL4 reactor under dismantling. Lessons got at this day and conclusions; Etude de l'origine des elements de la famille de l'uranium-235 observes en exces dans les environs du reacteur nucleaire experimental EL4 en cours de demantelement. Enseignements retires a ce jour et conclusion

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This study resumes the discovery of an excess of actinium 227 found around by EL4 nuclear reactor actually in dismantling. The search for the origin of this excess revealed a real inquiry of investigation during three years. Because a nuclear reactor existed in this area a particular attention will have concerned this region. The doubt became the line of conduct to find the answer to the human or natural origin of this excess. Finally and against any evidence, it appears that the origin of this phenomenon was natural, consequence of the particular local geology. The detail of the different investigations is given: search of a possible correlation with the composition of elevations constituent of lanes, search (and underlining) of new sites in the surroundings of the Rusquec pond and the Plouenez station, study of the atmospheric deposits under winds of the nuclear power plant and in the east direction, search of a possible relationship with the gaseous effluents of the nuclear power plant in the past, historical study of radioactive effluents releases in the fifty last years by the analysis of the sedimentary deposits in the Saint-Herbiot reservoir, search of a possible correlation between the excess of actinium 227 and the nuclear power plant activity; search of a possible correlation with a human activity without any relationship with the nuclear activities, search of a correlation with the underground waters, search of a correlation with the geological context, collect of information on the possible transfers in direction of the food chain, determination of the radiological composition of the underground waters ( not perturbed by human activity), search of the cause of an excess of actinium 227 in the old channel of liquid effluents release of the nuclear power plant. The results are given and discussed. And contrary to all expectations the origin of the excess of actinium 227 is completely natural. (N.C.)

  18. The discoveries of uranium 237 and symmetric fission — From the archival papers of Nishina and Kimura

    OpenAIRE

    IKEDA, Nagao

    2011-01-01

    Shortly before the Second World War time, Nishina reported on a series of prominent nuclear physical and radiochemical studies in collaboration with Kimura. They artificially produced 231Th, a member of the natural actinium series of nuclides, by bombarding thorium with fast neutrons. This resulted in the discovery of 237U, a new isotope of uranium, by bombarding uranium with fast neutrons, and confirmed that 237U disintegrates into element 93 with a mass number of 237. They also identified t...

  19. System for recovery of daughter isotopes from a source material

    Science.gov (United States)

    Tranter, Troy J [Idaho Falls, ID; Todd, Terry A [Aberdeen, ID; Lewis, Leroy C [Idaho Falls, ID; Henscheid, Joseph P [Idaho Falls, ID

    2009-08-04

    A method of separating isotopes from a mixture containing at least two isotopes in a solution is disclosed. A first isotope is precipitated and is collected from the solution. A daughter isotope is generated and collected from the first isotope. The invention includes a method of producing an actinium-225/bismuth-213 product from a material containing thorium-229 and thorium-232. A solution is formed containing nitric acid and the material containing thorium-229 and thorium-232, and iodate is added to form a thorium iodate precipitate. A supernatant is separated from the thorium iodate precipitate and a second volume of nitric acid is added to the thorium iodate precipitate. The thorium iodate precipitate is stored and a decay product comprising actinium-225 and bismuth-213 is generated in the second volume of nitric acid, which is then separated from the thorium iodate precipitate, filtered, and treated using at least one chromatographic procedure. A system for producing an actinium-225/bismuth-213 product is also disclosed.

  20. Dicty_cDB: Contig-U12768-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 165 ggngttncnanggccncatnaaangccnatcccctttangaaancnatccntcaggnggn 224 ||||||||||||||||||||||||||||||||||||||...|||||||||||||||||||||| Sbjct: 165 ggngttncnanggccncatnaaangccnatcccctttangaaancnatccntcaggnggn 224 Query: 225 gaaaatccna...|||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 225 gaaaatccnatttatnctagccccnattancngtaanaacttttnaaaat...ccatnaaaac 284 Query: 285 ccccnactcaaacccc 300 |||||||||||||||| Sbjct: 285 ccccnactcaaacccc 300 >Contig-U127...||||||||||||| ||| Sbjct: 99 gcccttggggtntttatttttgntggnaaaaaaggttntgnctactggaaancnanncaa 158 Query: 165 ggngttncnanggccncatnaaangccna

  1. 75 FR 8939 - Pesticide Products; Registration Applications

    Science.gov (United States)

    2010-02-26

    .... Product name: Spirotetramat Technical. Product type: Insecticide. Active ingredient: Spirotetramat at 97.... Product type: Insecticide. Active ingredient: Spirotetramat at 22.4%. PC Code: 392201. Proposed.... Product type: Insecticide. Active ingredient: Spirotetramat at 22.4%. PC Code: 392201....

  2. « Communities in Place and Communities in Space. Globalization and Féminism in Iran », in : Parvin Alizadeh, ed., The Economy of Iran: Dilemmas of an Islamic State. London - New York, Tauris, 2002, pp. 215-224.

    OpenAIRE

    Ladier-Fouladi, Marie

    2006-01-01

    Dans cet article, l’A. propose de montrer en premier lieu qu’en dépit de la politique discriminatoire de la République islamique, le statut de la femme s’est amélioré depuis 1979. En second lieu, il tente de déterminer les facteurs à l’origine de cette évolution. Pour l’A., la diffusion de l’école à une échelle géographique de plus en plus étendue et notamment l’accroissement du niveau d’instruction scolaire des femmes d’une part, et la globalisation, d’autre part, constituent les deux facteu...

  3. Hidden Cameras: Everything You Need to Know About Covert Recording, Undercover Cameras and Secret Filming Plomin Joe Hidden Cameras: Everything You Need to Know About Covert Recording, Undercover Cameras and Secret Filming 224pp £12.99 Jessica Kingsley 9781849056434 1849056439 [Formula: see text].

    Science.gov (United States)

    2016-08-01

    Last year, the Care Quality Commission issued guidance to families on using hidden cameras if they are concerned that their relatives are being abused or receiving poor care. The author was the undercover producer who exposed the abuse at Winterbourne View, near Bristol, in 2011 for BBC's Panorama. PMID:27484558

  4. Éléments d'hydromorphologie fluviale. Édité par l'Onema (Office national de l'eau et des milieux aquatiques, 2010, 224 p.En ligne sur : http://www.onema.fr/hydromorphologie-fluviale.

    Directory of Open Access Journals (Sweden)

    Jean-René Malavoi

    2011-02-01

    Full Text Available Le texte ci-dessous reproduit, à quelques détails près, le résumé qui accompagne l'ouvrage :Torrents, ruisseaux, rivières, fleuves, estuaires, deltas, autant de termes qui illustrent l'immense variété des cours d'eau qui sillonnent le territoire. Méandres, tresses, chutes, rapides, bras morts, chenaux, autant de caractéristiques visuelles qui nous sont familières alors même que nous n'en connaissons pas l'origine. Elles résultent en réalité de la combinaison subtile d'une quantité de caractéristiques naturelles ou non qui marquent le cours d'eau sur son passage : la nature de la roche mère dans laquelle il creuse son lit, le climat et la pente qui lui donnent sa puissance ou encore les activités humaines qui modifient son débit.L'ouvrage dévoile l'extraordinaire complexité des phénomènes mis en jeu dans la "fabrication" des cours d'eau. Il fait découvrir l'hydromorphologie fluviale, véritable discipline scientifique contemporaine, et explicite les caractéristiques géomorphologiques du lit mineur ou du lit majeur d'un cours d'eau, qui vont conditionner les grands types d'habitat pour les espèces aquatiques et terrestres qui en dépendent. Il apparaît ainsi que le bon fonctionnement écologique des cours d'eau et de leur corridor passe par la préservation et la restauration des processus géodynamiques naturels ainsi que des caractéristiques géomorphologiques qui leur sont associées.Quelques 400 illustrations combinant photographies et schémas explicitent ce que l'œil humain ne peut saisir et permettent d'approcher les différentes échelles auxquelles les phénomènes s'expriment, du galet jusqu'au bassin versant entier, voire au territoire.L'hydromorphologie fluviale s'avère aujourd'hui indispensable pour guider les orientations de gestion et de restauration des cours d'eau.

  5. Bis[μ-2-(2,4-difluorophenyl-1,3-bis(1,2,4-triazol-1-ylpropan-2-olato-κ4N2,O:O,N2′]bis[(acetato-κ2O,O′nickel(II] methanol hemisolvate

    Directory of Open Access Journals (Sweden)

    Feng Zhang

    2010-01-01

    Full Text Available In the title complex, [Ni2(C13H11F2N6O2(C2H3O22]·0.5CH3OH, there are two half-molecules in the asymmetric unit. The two centrosymmetrically related NiII atoms, each attached to an acetate ligand, are linked by two fluconazole ligands. Each NiII atom is six-coordinated in a distorted octahedral geometry by two N atoms of the triazole groups and two bridging O atoms from two different fluconazole ligands and two O atoms from a chelating acetate ligand. In the crystal structure, the half-occupied methanol solvent molecule is linked to a triazole group via an O—H...N hydrogen bond.

  6. Just 224 large donations from fewer than 60 sources accounted for two fifths of the donation income of the top three parties across a decade of British politics. This is far too narrow a base for the health of UK democracy

    OpenAIRE

    Wilks-Heeg, Stuart

    2010-01-01

    Why has reform of party funding in the UK been so troublesome for the body politic and steps to clean up the process so inadequate and hesitant? Using an in-depth analysis of party finances Stuart Wilks-Heeg exposes the myth that many small donors keep the major parties afloat. Instead he shows that the top three parties rely on attracting an average of just ten or eleven large donations a year between them from a tiny group of rich people, plus a few companies and large trade unions. This na...

  7. Hidden Cameras: Everything You Need to Know About Covert Recording, Undercover Cameras and Secret Filming Plomin Joe Hidden Cameras: Everything You Need to Know About Covert Recording, Undercover Cameras and Secret Filming 224pp £12.99 Jessica Kingsley 9781849056434 1849056439 [Formula: see text].

    Science.gov (United States)

    2016-05-27

    LAST YEAR, the Care Quality Commission issued guidance to families on using hidden cameras if they are concerned that their relatives are being abused or receiving poor care. Filming in care settings has also resulted in high profile prosecutions, and numerous TV documentaries. Joe Plomin, the author, was the undercover producer who exposed the abuse at Winterbourne View, near Bristol, in 2011. PMID:27231069

  8. 76 FR 7817 - Announcing Draft Federal Information Processing Standard 180-4, Secure Hash Standard, and Request...

    Science.gov (United States)

    2011-02-11

    ... 180-3 specifies five secure hash algorithms (SHAs): SHA-1, SHA- 224, SHA-256, SHA-384 and SHA-512. These algorithms produce 160, 224, 256, 384, and 512-bit outputs, respectively, which are called message... initialization hash value, ] adding two additional secure hash algorithms, SHA-512/224 and SHA-512/ 256, to...

  9. DISSOLVED CONCENTRATION LIMITS OF RADIOACTIVE ELEMENTS

    Energy Technology Data Exchange (ETDEWEB)

    P. Bernot

    2005-07-13

    The purpose of this study is to evaluate dissolved concentration limits (also referred to as solubility limits) of elements with radioactive isotopes under probable repository conditions, based on geochemical modeling calculations using geochemical modeling tools, thermodynamic databases, field measurements, and laboratory experiments. The scope of this activity is to predict dissolved concentrations or solubility limits for elements with radioactive isotopes (actinium, americium, carbon, cesium, iodine, lead, neptunium, plutonium, protactinium, radium, strontium, technetium, thorium, and uranium) relevant to calculated dose. Model outputs for uranium, plutonium, neptunium, thorium, americium, and protactinium are provided in the form of tabulated functions with pH and log fCO{sub 2} as independent variables, plus one or more uncertainty terms. The solubility limits for the remaining elements are either in the form of distributions or single values. Even though selection of an appropriate set of radionuclides documented in Radionuclide Screening (BSC 2002 [DIRS 160059]) includes actinium, transport of Ac is not modeled in the total system performance assessment for the license application (TSPA-LA) model because of its extremely short half-life. Actinium dose is calculated in the TSPA-LA by assuming secular equilibrium with {sup 231}Pa (Section 6.10); therefore, Ac is not analyzed in this report. The output data from this report are fundamental inputs for TSPA-LA used to determine the estimated release of these elements from waste packages and the engineered barrier system. Consistent modeling approaches and environmental conditions were used to develop solubility models for the actinides discussed in this report. These models cover broad ranges of environmental conditions so they are applicable to both waste packages and the invert. Uncertainties from thermodynamic data, water chemistry, temperature variation, and activity coefficients have been quantified or

  10. Detection of rare earth elements in Powder River Basin sub-bituminous coal ash using laser-induced breakdown spectroscopy (LIBS)

    Energy Technology Data Exchange (ETDEWEB)

    Tran, Phuoc [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State; Mcintyre, Dustin [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State

    2015-10-01

    We reported our preliminary results on the use of laser-induced breakdown spectroscopy to analyze the rare earth elements contained in ash samples from Powder River Basin sub-bituminous coal (PRB-coal). We have identified many elements in the lanthanide series (cerium, europium, holmium, lanthanum, lutetium, praseodymium, promethium, samarium, terbium, ytterbium) and some elements in the actinide series (actinium, thorium, uranium, plutonium, berkelium, californium) in the ash samples. In addition, various metals were also seen to present in the ash samples

  11. EST Table: FS873072 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS873072 E_FL_fner_50B18_R_0 10/09/28 91 %/224 aa ref|NP_001036841.1| Annexin IX is...oform A [Bombyx mori] dbj|BAA92809.1| annexin IX-A [Bombyx mori] 10/09/11 73 %/224 aa FBpp0280989|DpseGA1909...1|gene:ANXB9 10/09/10 62 %/224 aa gnl|Amel|GB16448-PA 10/09/10 73 %/224 aa gi|91092420|ref|XP_967931.1| PREDICTED: similar to Annexin IX CG5730-PC [Tribolium castaneum] FS780436 fner ...

  12. 78 FR 17719 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2013-03-22

    ... Ave., Columbia, 13000172 Newton County Neosho Wholesale Grocery Company, 224 N. Washington St., Neosho... Jackson County Buffington Island Battlefield (Boundary Increase), Roughly bounded by Ohio River, Dry...

  13. Low background counting of 222Rn, 220Rn and 219Rn with electrostatic counters

    Science.gov (United States)

    Mong, Brian; EXO-200 Collaboration; nEXO Collaboration

    2014-09-01

    The radon counting technique based on electrostatic precipitation of progenies in gas followed by alpha spectroscopy has been applied to support the material selection programs of low background, neutrino and dark matter experiments with emphasis on EXO. An array of 8 counters operated by Laurentian University at SNOLAB and the Waste Isolation Pilot Plant have reached the sensitivity of 10 atoms/day in the uranium, thorium and actinium chains. Hardware improvements are underway to further increase the capacity and sensitivity in support of nEXO. The radon counting technique based on electrostatic precipitation of progenies in gas followed by alpha spectroscopy has been applied to support the material selection programs of low background, neutrino and dark matter experiments with emphasis on EXO. An array of 8 counters operated by Laurentian University at SNOLAB and the Waste Isolation Pilot Plant have reached the sensitivity of 10 atoms/day in the uranium, thorium and actinium chains. Hardware improvements are underway to further increase the capacity and sensitivity in support of nEXO. Supported by NSERC Project Grants ``Search for Double Beta Decay with EXO.''

  14. Purification of cerium, neodymium and gadolinium for low background experiments

    Science.gov (United States)

    Boiko, R. S.; Barabash, A. S.; Belli, P.; Bernabei, R.; Cappella, F.; Cerulli, R.; Danevich, F. A.; Incicchitti, A.; Laubenstein, M.; Mokina, V. M.; Nisi, S.; Poda, D. V.; Polischuk, O. G.; Tretyak, V. I.

    2014-01-01

    Cerium, neodymium and gadolinium contain double beta active isotopes. The most interesting are 150Nd and 160Gd (promising for 0ν2β search), 136Ce (2β+ candidate with one of the highest Q2β). The main problem of compounds containing lanthanide elements is their high radioactive contamination by uranium, radium, actinium and thorium. The new generation 2β experiments require development of methods for a deep purification of lanthanides from the radioactive elements. A combination of physical and chemical methods was applied to purify cerium, neodymium and gadolinium. Liquid-liquid extraction technique was used to remove traces of Th and U from neodymium, gadolinium and for purification of cerium from Th, U, Ra and K. Co-precipitation and recrystallization methods were utilized for further reduction of the impurities. The radioactive contamination of the samples before and after the purification was tested by using ultra-low-background HPGe gamma spectrometry. As a result of the purification procedure the radioactive contamination of gadolinium oxide (a similar purification efficiency was reached also with cerium and neodymium oxides) was decreased from 0.12 Bq/kg to 0.007 Bq/kg in 228Th, from 0.04 Bq/kg to <0.006 Bq/kg in 226Ra, and from 0.9 Bq/kg to 0.04 Bq/kg in 40K. The purification methods are much less efficient for chemically very similar radioactive elements like actinium, lanthanum and lutetium.

  15. Mixed valency of the RE and Ac ions in solid states

    International Nuclear Information System (INIS)

    Full text: This review is devoted to consideration of the methods and results of the theoretical and experimental investigations of the electronic state of the rare earths and actinium ions in the separate compound. The methods of the high resolution X ray spectroscopy were used for our consideration. Energy of the X ray lines of the rare earths and actinium ions in free state and solid states was study carefully. Valency shifts of X Ray lines under change of electronic state of nf - ions in different oxide, fluoride and chloride compounds were determined for K -, L- and M - lines for these ions with accuracy near 10 -100 MeV. We studied the electronic state of nf- ions which is changed from '+2' to '+4' and determined the concentration of ions in different electronic state. Relative error for theoretical energy of the most lines for HFP - approach in comparison with experiment is less than 0.5%, and deviation for concentration is less than 5%

  16. The Technological Enhancement of Normally Occurring Radioactive Materials in Red Mud due to the Production of Alumina

    Directory of Open Access Journals (Sweden)

    Maurice O. Miller

    2016-01-01

    Full Text Available This study investigates the level of technological enhancement of normally occurring radioactive materials (TENORM in the red mud waste due to the production of alumina in Jamaica. Technological enhancements factors (TEF were determined for the uranium, thorium, actinium series, their progenies, and the nonseries potassium-40 using gamma spectrometry. The study concluded that bauxite production technologically enhances the uranium progenies Th-234, Pb-214, Bi-214, and Pa-234 and the thorium-232 progenies Ac-228, Pb-212, and Bi-212 in red mud. The actinium series was technologically enhanced, but K-40 and the thorium daughter, Tl-208, were reduced. The spectrometric comparison of Tl-208 (at 510 keV was unexpected since its other photopeaks at 583 keV, 934 keV, and 968 keV were markedly different. An explanation for this anomaly is discussed. An explanation regarding the process of accumulation and fractionation of organically derived phosphate deposits and potassium-feldspar is offered to explain the spectrometric differences between the alumina product and its waste material, red mud.

  17. A study of uranium and thorium migration at the Koongarra uranium deposit with application to actinide transport from nuclear waste repositories

    International Nuclear Information System (INIS)

    One way to gain confidence in modelling possible radionuclide releases is to study natural systems which are similar to components of the multibarrier waste repository. Several such analogues are currently under study and these provide useful data about radionuclide behaviour in the natural environment. One such system is the Koongarra uranium deposit in the Northern Territory. In this dissertation, the migration of actinides, primarily uranium and thorium, has been studied as an analogue for the behaviour of transuranics in the far-field of a waste repository. The major findings of this study are: 1. the main process retarding uranium migration in the dispersion fan at Koongarra is sorption, which suppresses dissolved uranium concentrations well below solubility limits, with ferrihydrite being a major sorbing phase; 2. thorium is extremely immobile, with very low dissolved concentrations and corresponding high distribution ratios for 230Th. Overall, it is estimated that colloids are relatively unimportant in Koongarra groundwater. Uranium migrates mostly as dissolved species, whereas thorium and actinium are mostly adsorbed to larger, relatively immobile particles and the stationary phase. However, of the small amount of 230Th that passes through a 1μm filter, a significant proportion is associated with colloidal particles. Actinium appears to be slightly more mobile than thorium and is associated with colloids to a greater extent, although generally present in low concentrations. These results support the possibility of colloidal transport of trivalent and tetravalent actinides in the vicinity of a nuclear waste repository. 112 refs., 23 tabs., 32 figs

  18. Purification of cerium, neodymium and gadolinium for low background experiments

    Directory of Open Access Journals (Sweden)

    Boiko R.S.

    2014-01-01

    Full Text Available Cerium, neodymium and gadolinium contain double beta active isotopes. The most interesting are 150Nd and 160Gd (promising for 0ν2β search, 136Ce (2β+ candidate with one of the highest Q2β. The main problem of compounds containing lanthanide elements is their high radioactive contamination by uranium, radium, actinium and thorium. The new generation 2β experiments require development of methods for a deep purification of lanthanides from the radioactive elements. A combination of physical and chemical methods was applied to purify cerium, neodymium and gadolinium. Liquid-liquid extraction technique was used to remove traces of Th and U from neodymium, gadolinium and for purification of cerium from Th, U, Ra and K. Co-precipitation and recrystallization methods were utilized for further reduction of the impurities. The radioactive contamination of the samples before and after the purification was tested by using ultra-low-background HPGe gamma spectrometry. As a result of the purification procedure the radioactive contamination of gadolinium oxide (a similar purification efficiency was reached also with cerium and neodymium oxides was decreased from 0.12 Bq/kg to 0.007 Bq/kg in 228Th, from 0.04 Bq/kg to <0.006 Bq/kg in 226Ra, and from 0.9 Bq/kg to 0.04 Bq/kg in 40K. The purification methods are much less efficient for chemically very similar radioactive elements like actinium, lanthanum and lutetium.

  19. Charges in the cytoplasmic pore control intrinsic inward rectification and single-channel properties in Kir1.1 and Kir2.1 channels.

    Science.gov (United States)

    Chang, Hsueh-Kai; Yeh, Shih-Hao; Shieh, Ru-Chi

    2007-02-01

    An E224G mutation of the Kir2.1 channel generates intrinsic inward rectification and single-channel fluctuations in the absence of intracellular blockers. In this study, we showed that positively charged residues H226, R228 and R260, near site 224, regulated the intrinsic inward rectification and single-channel properties of the E224G mutant. By carrying out systematic mutations, we found that the charge effect on the intrinsic inward rectification and single-channel conductance is consistent with a long-range electrostatic mechanism. A Kir1.1 channel where the site equivalent to E224 in the Kir2.1 channel is a glycine residue does not show inward rectification or single-channel fluctuations. The G223K and N259R mutations of the Kir1.1 channel induced intrinsic inward rectification and reduced the single-channel conductance but did not generate large open-channel fluctuations. Substituting the cytoplasmic pore of the E224G mutant into the Kir1.1 channel induced open-channel fluctuations and intrinsic inward rectification. The single-channel conductance of the E224G mutant showed inward rectification. Also, a voltage-dependent gating mechanism decreased open probability during depolarization and contributed to the intrinsic inward rectification in the E224G mutant. In addition to an electrostatic effect, a close interaction of K(+) with channel pore may be required for generating open-channel fluctuations in the E224G mutant.

  20. 77 FR 16800 - Radio Broadcasting Services; Dermott, AR, and Cleveland, MS

    Science.gov (United States)

    2012-03-22

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Dermott, AR, and Cleveland, MS AGENCY: Federal... Allotments by substituting Channel 224A for vacant Channel 289A, at Dermott, Arkansas, and by substituting... ``hybrid'' application and rule making petition. Channel 224A can be allotted at Dermott, Arkansas,...

  1. 78 FR 27306 - Radio Broadcasting Services; Dermott, Arkansas, and Cleveland, Mississippi

    Science.gov (United States)

    2013-05-10

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Dermott, Arkansas, and Cleveland, Mississippi AGENCY... Delta Radio Network, LLC, substitutes FM Channel 224A for 289A at Dermott, Arkansas, and substitutes FM...-20110913AAK. Channel 224A can be allotted at Dermott with a site restriction of 3.5 km (2.2 miles)...

  2. 75 FR 53681 - Office of Elementary and Secondary Education Overview Information; Advanced Placement (AP) Test...

    Science.gov (United States)

    2010-09-01

    ... address: Francisco Ramirez, U.S. Department of Education, 400 Maryland Avenue, SW., Room 3E224, Washington, DC 20202-6200. Telephone: (202) 260-1541 or by e-mail: francisco.ramirez@ed.gov . If you use a...: Francisco Ramirez, U.S. Department of Education, 400 Maryland Avenue, SW., Room 3E224, Washington, DC...

  3. Drug: D07321 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D07321 Drug Vinylbital (INN); Vinylbitone C11H16N2O3 224.1161 224.2563 D07321.gif A...HOLEPTICS N05C HYPNOTICS AND SEDATIVES N05CA Barbiturates, plain N05CA08 Vinylbital D07321 Vinylbital (INN)

  4. 42 CFR 441.16 - Home health agency requirements for surety bonds; Prohibition on FFP.

    Science.gov (United States)

    2010-10-01

    ... to 9308 and 31 CFR parts 223, 224, and 225, provided the bond otherwise meets the requirements of... U.S. Department of the Treasury in accordance with 31 U.S.C. 9304 to 9308 and 31 CFR parts 223, 224... Order No. 12549 (3 CFR 1986 Comp., p. 189). (g) Amount of the bond—(1) Basic rule. The amount of...

  5. Commemoration as Conflict: Space, Memory and Identity in Peace Processes

    DEFF Research Database (Denmark)

    McQuaid, Sara Dybris

    2015-01-01

    Book rewiew: Commemoration as Conflict: Space, Memory and Identity in Peace Processes / Sara McDowell and Maire Braniff Palgrave Macmillan, 2014, 224pp., ISBN 978-0-230-27375-7......Book rewiew: Commemoration as Conflict: Space, Memory and Identity in Peace Processes / Sara McDowell and Maire Braniff Palgrave Macmillan, 2014, 224pp., ISBN 978-0-230-27375-7...

  6. 76 FR 30641 - Notice of Funding Availability (NOFA) for Loan Guarantees Under Section 538 Guaranteed Rural...

    Science.gov (United States)

    2011-05-26

    ..., 771 Corporate Drive, Suite 200, Lexington, KY 40503, (859) 224-7300, TDD (859) 224-7422. Louisiana..., Salt Lake City, UT 84138, (801) 524-4320, TDD (801) 524-3309. Vermont State Office, City Center, 3rd... or Housing Finance Agency (HFA) in good standing in the state or states where it conducts...

  7. Predictive Value of Morphological Features in Patients with Autism versus Normal Controls

    NARCIS (Netherlands)

    Ozgen, H.; Hellemann, G. S.; de Jonge, M. V.; Beemer, F. A.; van Engeland, H.

    2013-01-01

    We investigated the predictive power of morphological features in 224 autistic patients and 224 matched-pairs controls. To assess the relationship between the morphological features and autism, we used the receiver operator curves (ROC). In addition, we used recursive partitioning (RP) to determine

  8. 75 FR 22095 - Notice of Funds Availability for the Section 533 Housing Preservation Grants for Fiscal Year 2010

    Science.gov (United States)

    2010-04-27

    ... OMB and published in the Federal Register on June 27, 2003 (68 FR 38402-38405). The Department of..., Kentucky 40503 (859) 224-7325 TDD (859) 224-7422 Beth Moore Louisiana State Office 3727 Government Street... 82602-5006 (307) 233-6716 TDD (307) 233-6733 Alan Brooks FOR FURTHER INFORMATION CONTACT: For...

  9. En frygtindgydende munterhed

    DEFF Research Database (Denmark)

    Haarder, Jon Helt

    2008-01-01

    Imre Kertész: DOSSIER K. (K. dosszié). Oversat fra ungarsk. af Peter Eszerhás. 224 sider, 248 kr. Batzer og co. Er udkommet. Fem stjerner.......Imre Kertész: DOSSIER K. (K. dosszié). Oversat fra ungarsk. af Peter Eszerhás. 224 sider, 248 kr. Batzer og co. Er udkommet. Fem stjerner....

  10. A novel antagonist anti-cMet antibody with antitumor activities targeting both ligand-dependent and ligand-independent c-Met receptors.

    Science.gov (United States)

    Gonzalez, Alexandra; Broussas, Matthieu; Beau-Larvor, Charlotte; Haeuw, Jean-François; Boute, Nicolas; Robert, Alain; Champion, Thierry; Beck, Alain; Bailly, Christian; Corvaïa, Nathalie; Goetsch, Liliane

    2016-10-15

    c-Met is a prototypic member of a sub-family of RTKs. Inappropriate c-Met activation plays a crucial role in tumor formation, proliferation and metastasis. Using a key c-Met dimerization assay, a set of 12 murine whole IgG1 monoclonal antibodies was selected and a lead candidate, m224G11, was humanized by CDR-grafting and engineered to generate a divalent full antagonist humanized IgG1 antibody, hz224G11. Neither m224G11 nor hz224G11 bind to the murine c-Met receptor. Their antitumor activity was investigated in vitro in a set of experiments consistent with the reported pleiotropic effects mediated by c-Met and, in vivo, using several human tumor xenograft models. Both m224G11 and hz224G11 exhibited nanomolar affinities for the receptor and inhibited HGF binding, c-Met phosphorylation, and receptor dimerization in a similar fashion, resulting in a profound inhibition of all c-Met functions in vitro. These effects were presumably responsible for the inhibition of c-Met's major functions including cell proliferation, migration, invasion scattering, morphogenesis and angiogenesis. In addition to these in vitro properties, hz224G11 dramatically inhibits the growth of autocrine, partially autophosphorylated and c-Met amplified cell lines in vivo. Pharmacological studies performed on Hs746T gastric cancer xenografts demonstrate that hz224G11 strongly downregulates c-Met expression and phosphorylation. It also decreases the tumor mitotic index (Ki67) and induces apoptosis. Taken together, the in vitro and in vivo data suggest that hz224G11 is a promising candidate for the treatment of tumors. This antibody, now known as ABT-700 and currently in Phase I clinical trials, may provide a novel therapeutic approach to c-Met-expressing cancers.

  11. A novel antagonist anti-cMet antibody with antitumor activities targeting both ligand-dependent and ligand-independent c-Met receptors.

    Science.gov (United States)

    Gonzalez, Alexandra; Broussas, Matthieu; Beau-Larvor, Charlotte; Haeuw, Jean-François; Boute, Nicolas; Robert, Alain; Champion, Thierry; Beck, Alain; Bailly, Christian; Corvaïa, Nathalie; Goetsch, Liliane

    2016-10-15

    c-Met is a prototypic member of a sub-family of RTKs. Inappropriate c-Met activation plays a crucial role in tumor formation, proliferation and metastasis. Using a key c-Met dimerization assay, a set of 12 murine whole IgG1 monoclonal antibodies was selected and a lead candidate, m224G11, was humanized by CDR-grafting and engineered to generate a divalent full antagonist humanized IgG1 antibody, hz224G11. Neither m224G11 nor hz224G11 bind to the murine c-Met receptor. Their antitumor activity was investigated in vitro in a set of experiments consistent with the reported pleiotropic effects mediated by c-Met and, in vivo, using several human tumor xenograft models. Both m224G11 and hz224G11 exhibited nanomolar affinities for the receptor and inhibited HGF binding, c-Met phosphorylation, and receptor dimerization in a similar fashion, resulting in a profound inhibition of all c-Met functions in vitro. These effects were presumably responsible for the inhibition of c-Met's major functions including cell proliferation, migration, invasion scattering, morphogenesis and angiogenesis. In addition to these in vitro properties, hz224G11 dramatically inhibits the growth of autocrine, partially autophosphorylated and c-Met amplified cell lines in vivo. Pharmacological studies performed on Hs746T gastric cancer xenografts demonstrate that hz224G11 strongly downregulates c-Met expression and phosphorylation. It also decreases the tumor mitotic index (Ki67) and induces apoptosis. Taken together, the in vitro and in vivo data suggest that hz224G11 is a promising candidate for the treatment of tumors. This antibody, now known as ABT-700 and currently in Phase I clinical trials, may provide a novel therapeutic approach to c-Met-expressing cancers. PMID:27144973

  12. Radionuclide interactions with marine sediments

    International Nuclear Information System (INIS)

    A critical review of the literature on the subject of the interactions of radionuclides with marine sediments has been carried out. On the basis of the information available, an attempt has been made to give ranges and 'best estimates' for the distribution ratios between seawater and sediments. These estimates have been based on an understanding of the sediment seawater system and the porewater chemistry and mineralogy. Field measurements, laboratory measurements and estimates based on stable-element geochemical data are all taken into account. Laboratory measurements include distribution-ratio and diffusion-coefficient determinations. The elements reviewed are carbon, chlorine, calcium, nickel, selenium, strontium, zirconium, niobium, technetium, tin, iodine, caesium, lead, radium, actinium, thorium, protactinium, uranium, neptunium, plutonium, americium and curium. (author)

  13. Process for radioisotope recovery and system for implementing same

    Science.gov (United States)

    Meikrantz, David H.; Todd, Terry A.; Tranter, Troy J.; Horwitz, E. Philip

    2007-01-02

    A method of recovering daughter isotopes from a radioisotope mixture. The method comprises providing a radioisotope mixture solution comprising at least one parent isotope. The at least one parent isotope is extracted into an organic phase, which comprises an extractant and a solvent. The organic phase is substantially continuously contacted with an aqueous phase to extract at least one daughter isotope into the aqueous phase. The aqueous phase is separated from the organic phase, such as by using an annular centrifugal contactor. The at least one daughter isotope is purified from the aqueous phase, such as by ion exchange chromatography or extraction chromatography. The at least one daughter isotope may include actinium-225, radium-225, bismuth-213, or mixtures thereof. A liquid-liquid extraction system for recovering at least one daughter isotope from a source material is also disclosed.

  14. Proposed training program for construction personnel involved in remedial action work at sites contaminated by naturally occurring radionuclides

    International Nuclear Information System (INIS)

    Many sites used during the early days of the US atomic energy program are contaminated with radionuclides of the primordial decay chains (uranium, thorium, and actinium series). This contamination consists of residues resulting from refining and processing uranium and thorium. Preparation of these sites for release to unrestricted private use will involve the assistance of construction workers, many of whom have limited knowledge of the hazards associated with radioactive materials. Therefore, there is a need to educate these workers in the fundamentals of radioactive material handling to minimize exposures and possible spread of contamination. This training should disseminate relevant information at an appropriate educational level and should instill a cautious, common-sense attitude toward the handling of radioactive materials. The training should emphasize basic information concerning environmental radiation within a context of relative risk. A multi-media format, including colorful visual aids, demonstration, and discussion, should be used to maximize motivation and retention. A detailed, proposed training program design is presented

  15. JAEA thermodynamic database for performance assessment of geological disposal of high-level and TRU wastes. Refinement of thermodynamic data for trivalent actinoids and samarium

    International Nuclear Information System (INIS)

    Within the scope of the JAEA thermodynamic database project for performance assessment of geological disposal of high-level radioactive and TRU wastes, the refinement of the thermodynamic data for the inorganic compounds and complexes of trivalent actinoids (actinium(III), plutonium(III), americium(III) and curium(III)) and samarium(III) was carried out. Refinement of thermodynamic data for these elements was based on the thermodynamic database for americium published by the Nuclear Energy Agency in the Organisation for Economic Co-operation and Development (OECD/NEA). Based on the similarity of chemical properties among trivalent actinoids and samarium, complementary thermodynamic data for their species expected under the geological disposal conditions were selected to complete the thermodynamic data set for the performance assessment of geological disposal of radioactive wastes. (author)

  16. Theoretical Study on Properties of New Isotope 265Bh

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The properties of nuclei belonging to the newly observed α-decay chain starting from 265Bh have been studied. The axially deformed relativistic mean-field calculation with the force NL-Z2 has been performed in the blockedBCS approximation. Some ground state properties such as binding energies, deformations, spins, and parities, as well as Q-values of the α-decay for this decay chain have been calculated and compared with known experimental data. Good agreement is found. The single-particle spectrum of the nucleus 265 Bh is studied and some new magic numbers are found,while the magnitudes of the shell gaps in superheavy nuclei are much smaller than those of nuclei before the actinium region, and the Fermi surfaces are close to the continuum. Thus the superheavy nuclei are usually not stable. The The methods which give good agreement with the data are selected.

  17. Analysis of Ancestral and Functionally Relevant CD5 Variants in Systemic Lupus Erythematosus Patients

    OpenAIRE

    Maria Carmen Cenit; Mario Martínez-Florensa; Marta Consuegra; Lizette Bonet; Elena Carnero-Montoro; Noelia Armiger; Miguel Caballero-Baños; Maria Teresa Arias; Daniel Benitez; Norberto Ortego-Centeno; Enrique de Ramón; José Mario Sabio; García-Hernández, Francisco J; Carles Tolosa; Ana Suárez

    2014-01-01

    Objective: CD5 plays a crucial role in autoimmunity and is a well-established genetic risk factor of developing RA. Recently, evidence of positive selection has been provided for the CD5 Pro224-Val471 haplotype in East Asian populations. The aim of the present work was to further analyze the functional relevance of non-synonymous CD5 polymorphisms conforming the ancestral and the newly derived haplotypes (Pro224-Ala471 and Pro224-Val471, respectively) as well as to investigate the potential r...

  18. Distribution characteristics of radium isotopes and their influence factors in the water of Jiaozhou Bay area

    International Nuclear Information System (INIS)

    Background: The interaction between continental and oceanic process is much intense in coastal region. The terrestrial freshwater mixes with seawater here which leads to the chemical constituents in water undergo rapid change. Purpose: The aim is to analyze and study the distribution characteristics of 224Ra and 226Ra and their influence factors in the water of Jiaozhou Bay area. Methods: The water samples of 224Ra and 226Ra were collected from groundwater, river water and seawater around the Jiaozhou Bay from April to May, 2012. In the laboratory, the activities of 224Ra absorbed on the Mn-fiber were measured through the continuous emanation method. Finally, the Mn-fiber was sealed for more than 7 days, and the activities of 226Ra absorbed on the Mn-fiber were measured through the direct emanation method. Results: The results show that the activities of 224Ra and 226Ra in groundwater and river water are much higher in the granitic area which has higher concentration of 232Th and 238U. Because of mixing with seawater, the salinity of groundwater and river water in coastal region rises which leads to the increasing amounts of 224Ra and 226Ra desorbed from the particles, resulting in higher activities of 224Ra and 226Ra in coastal region. Affected by the input of river (dissolved and desorbed from suspended particles) and submarine groundwater discharge (SGD), the activities of 224Ra and 226Ra are relatively higher in nearshore seawater, then with the decay of 224Ra and mixing dilution effect of the offshore seawater, the activities of 224Ra gradually decrease from nearshore region to the open ocean. The activities of 226Ra in the seawater of Jiaozhou Bay remain high-level values, and there are only a few zones of low 226Ra activities. The main reasons are that the activities of 226Ra from terrestrial freshwater are close to those from offshore seawater and the half-life of 226Ra is very long. Conclusion: The activities of 224Ra and 226Ra in groundwater relate to the

  19. Alice Munro: A Bibliography

    OpenAIRE

    Bigot, Corinne

    2014-01-01

    I. Collections of short stories by Alice Munro Dance of the Happy Shades, Toronto, Ryerson Press, 1968, 224 pp; New York, McGraw Hill, 1973, 224 pp; London, Allen Lane, 1974, 224 pp. Lives of Girls and Women, Toronto, McGraw Hill Ryerson, 1971, 254 pp; New York,McGraw Hill, 1972, 250 pp; London, Allen Lane, 1974, 250 pp. Something I’ve Been Meaning To Tell You, Toronto and New York, McGraw-Hill Ryerson, 1974, 246 pp. Who Do You Think You Are?, Toronto, Macmillan, 1974, 206 pp. Printed in the ...

  20. Origin of elements of the Uranium-235 family observed in the Ellez river near the EL-4 experimental nuclear reactor in dismantling (Monts d'Arree- Finistere department); Origine des elements de la famille de l'uranium-235 observes dans la riviere Ellez a proximite du reacteur nucleaire experimental EL4 en cours de demantelement (Mont d'Arree - departement du Finistere). Resultats et premiers constats annee 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    In a previous study which concerned the catchment basin of the harbour of Brest, the A.C.R.O. put in evidence a marking by artificial radioelements around the power plant of Brennilis which can be imputed without ambiguities to the nuclear installation. It also put in evidence abnormalities concerning the natural radioactivity which justifies this new study. In the area of the Monts d'Arree, actinium 227 ({sup 227}Ac), non born by its ascendents which are {sup 235}U and {sup 231}Pa is observed. This phenomenon is characterized by mass activities superior to these ones of {sup 235}U and able to reach these ones of {sup 238}U. Its presence corresponds with the drainage of the Ellez river since the former channel of radioactive effluents releases from the nuclear power plant EL-4 up to the reservoir Saint-Herblot situated 6 km downstream. The strongest values of radioactivity are registered near the disused power plant, at this place a relationship exists between the level of actinium 227 and this one of the artificial radioactivity as it exists a relationship with the decay products of radon exhaled from the subsoil ({sup 210}Pb). But its presence is not limited to a part of the Ellez river, it is equally observed in terrestrial medium, in places in priori not influenced by the direct liquid effluents of the power plant. This place is situated at more than 4 km and without any connection with the Ellez waters. At this stage of the study, it is not possible to answer with certainty the question of the origin of this phenomenon. A new reorientation is considered indispensable to clarify definitively the origin of this unknown phenomenon in the scientific publications and the environmental monitoring. (N.C.)

  1. origin of elements of the Uranium-235 family observed in the Ellez river near the EL-4 experimental nuclear reactor in dismantling (Monts d'Arree- Finistere department)

    International Nuclear Information System (INIS)

    In a previous study which concerned the catchment basin of the harbour of Brest, the A.C.R.O. put in evidence a marking by artificial radioelements around the power plant of Brennilis which can be imputed without ambiguities to the nuclear installation. It also put in evidence abnormalities concerning the natural radioactivity which justifies this new study. In the area of the Monts d'Arree, actinium 227 (227Ac), non born by its ascendents which are 235U and 231Pa is observed. This phenomenon is characterized by mass activities superior to these ones of 235U and able to reach these ones of 238U. Its presence corresponds with the drainage of the Ellez river since the former channel of radioactive effluents releases from the nuclear power plant EL-4 up to the reservoir Saint-Herblot situated 6 km downstream. The strongest values of radioactivity are registered near the disused power plant, at this place a relationship exists between the level of actinium 227 and this one of the artificial radioactivity as it exists a relationship with the decay products of radon exhaled from the subsoil (210Pb). But its presence is not limited to a part of the Ellez river, it is equally observed in terrestrial medium, in places in priori not influenced by the direct liquid effluents of the power plant. This place is situated at more than 4 km and without any connection with the Ellez waters. At this stage of the study, it is not possible to answer with certainty the question of the origin of this phenomenon. A new reorientation is considered indispensable to clarify definitively the origin of this unknown phenomenon in the scientific publications and the environmental monitoring. (N.C.)

  2. Disease: H00021 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ium production Cadmium and cadmium compounds Chimney sweeping Radium-224 and its decay products Shale-oils Tobacco smoking... Secretan MB, Straif K. Tobacco smoking and cancer: a brief review of recent epidemiological evidence. Lung

  3. 76 FR 81962 - Notice of Public Meeting: Joint Session of Northeast California Resource Advisory Council and...

    Science.gov (United States)

    2011-12-29

    ... in the Conference Center of the Oxford Suites Hotel, 1967 Hilltop Dr., Redding, California. FOR FURTHER INFORMATION CONTACT: Nancy Haug, BLM Northern California District manager, (530) 224-2160;...

  4. Festivalipäevik III / Margaret Tali, Anu Allas, Margit Tõnson...[jt.

    Index Scriptorium Estoniae

    2005-01-01

    Rahvusvaheline NU Performance festival "Continental Breakfast" Tallinnas Kanuti Gildi saalis 2.-24. nov. 2005. Hollandlase Kim H. Veltmani loengu formaadis performance "World tree". Katrin Essensoni performance "Designed to make difference". Gob Squad (Saksamaa/Inglismaa) "Super Night Shot".

  5. 77 FR 41436 - Announcement of Funding Awards; Fair Housing Initiatives Program Fiscal Year 2012

    Science.gov (United States)

    2012-07-13

    ...,000.00 16503. Legal Aid of North Carolina, Inc., 224 S. Dawson Jeffrey Dillman, 919-861-1884. 4 325... 101, Tucson, AZ 85719. Fair Housing Center of Washington, 1517 South Fawcett, Lauren Walker,...

  6. 78 FR 22025 - Eighteenth Meeting: RTCA Special Committee 214, Standards for Air Traffic Data Communication...

    Science.gov (United States)

    2013-04-12

    ... & Change 1 to DO-281B (Dongsong Zeng) Approve TOR Chagens to add to the SC deliverables Change 1 to DO-224C... Communications Including Compatibility with Digital Voice Techniques'' Approve TOR Changes to add to the...

  7. 17 CFR 242.402 - General provisions.

    Science.gov (United States)

    2010-04-01

    ... Regulation T, U or X of the Board of Governors of the Federal Reserve System (12 CFR parts 220, 221, and 224...) REGULATIONS M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Customer...

  8. Training-based Channel Estimation for Signal Equalization and OPM in 16-QAM Optical Transmission Systems

    DEFF Research Database (Denmark)

    Pittalà, Fabio; Hauske, Fabian N.; Ye, Yabin;

    2012-01-01

    Efficient channel estimation for signal equalization and OPM based on short CAZAC sequences with QPSK and 8PSK constellation formats is demonstrated in a 224-Gb/s PDM 16-QAM optical linear transmission system....

  9. Dicty_cDB: FC-IC1465 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available its) Value N ( AU272514 ) Dictyostelium discoideum gamete cDNA clone:FC-IC1... 232 2e-84 2 ( AU275020 ) Dictyostelium discoideum game...te cDNA clone:FC-IC1... 232 7e-57 1 ( AU275231 ) Dictyostelium discoideum gamete... cDNA clone:FC-IC1... 224 2e-54 1 ( AU275222 ) Dictyostelium discoideum gamete cDNA ...clone:FC-IC1... 224 2e-54 1 ( AU275176 ) Dictyostelium discoideum gamete cDNA clone:FC-IC1... 224 2e-54 1 ( ...AU275175 ) Dictyostelium discoideum gamete cDNA clone:FC-IC1... 224 2e-54 1 ( AU2

  10. Protein (Cyanobacteria): 286149 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available YP_007068440.1 1117:4890 1161:684 1185:224 1186:169 99598:92 diguanylate cyclase with PAS/PAC and Chase2 sen...sors Calothrix sp. PCC 7507 MSKQLGKCLVKFIFGLKQSLGRGHRELITASSVVICILFLRSIGLLQFLELAALD

  11. Port Facilities - PORTS_NTAD_IN: Ports in Indiana derived from the U.S. Army Corps of Engineers (Bureau of Transportation Statistics, 1:100,000, Point Shapefile)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — The U.S. Army Corps of Engineers (USACE) Ports database is an extract from the National Waterway Network database consisting of 224 points coded as U.S. Army Corps...

  12. 21 CFR 177.2420 - Polyester resins, cross-linked.

    Science.gov (United States)

    2010-04-01

    ... propylene oxide). Propylene glycol. Sorbitol. Trimethylol ethane. Trimethylol propane. 2,2,4-Trimethyl-1,3... with good manufacturing practice, finished articles containing the cross-linked polyester resins...

  13. Gene : CBRC-MDOM-01-0486 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available ca sperm protein Sp17 (SP17), mRNA /cds=p(364,903) /gb=NM_001032992 /gi=74136538 /ug=Mdm.224 /len=1105 0.012 26% MKERQTERKKDREKERK...KERKREGKKERKKERKKERKKERKKERKRERKKERQRERKKDREKERKRERKKERKKERKKERKKERKKERKKERKKERKKERK...KERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKKSWFWKELLRPTNPTSPSLQMRKLRPRGVK ...

  14. Gene : CBRC-MDOM-03-0169 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available ca sperm protein Sp17 (SP17), mRNA /cds=p(364,903) /gb=NM_001032992 /gi=74136538 /ug=Mdm.224 /len=1105 0.041 23% MVERERKKERKKERKKERK...KERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKEREKERKRERKKGRKEGRKEGRKEGEERKEERKKERK...EGRKKERKKERKKERKKERKKERKKERKKDKNEERQQERKKERKQEREKERMRERERERKKERKKERKKERKKERKKERKKERKKERKKERKKERKKGRKKERKEGRKEGRKEGRKEGRKEREEGRKDLRAYYVSSTL ...

  15. Efficacy of tepronone and folic acid in the treatment of chronic atrophic gastritis evaluated by the marking targeting biopsy

    Institute of Scientific and Technical Information of China (English)

    裘力锋

    2013-01-01

    Objective To explore the efficacy of tepronone and folic acid in the treatment of chronic atrophic gastritis(CAG) evaluated by the marking targeting biopsy(MTB).Methods A total of 224 H.pylori negative

  16. Characteristics of Radium Desorption from Sediments in the Salt Water Environment%咸水环境下沉积物中镭的解吸特点

    Institute of Scientific and Technical Information of China (English)

    袁晓婕; 郭占荣; 刘洁; 马志勇; 王博

    2014-01-01

    海底沉积物向上覆水体扩散的镭是海洋水体中镭同位素的重要来源之一。为了研究沉积物中镭同位素的解吸和扩散特点,进行了不同盐度和不同粒度条件下224Ra 和226Ra解吸的模拟实验,并通过多个时间段的沉积物培养实验获取224Ra和226Ra的扩散通量。实验结果表明:随着水体盐度增大,沉积物中224Ra、226Ra的解吸量随之增加,在盐度为25时,解吸量基本达到最大值;在同一咸水环境条件下,4个粒级(2000~1000μm、1000~500μm、500~250μm、250~125μm)的沉积物的224Ra、226Ra解吸量比较接近,粒级>2000μm的224Ra、226Ra解吸量略高于上述4个粒级,而粒级<125μm的224Ra、226Ra解吸量远大于上述5个粒级;胶州湾沉积物中224Ra和226Ra的平均扩散通量分别为0.85 Bq•m-2•d-1和0.022 Bq•m-2•d-1。%Radium diffusion from sediments to overlying water is one of the important sources of radium isotopes in ocean water. A series of laboratory desorption/diffusion experiments were conducted to help elucidate the characteristics of sediments on224Ra and226Ra desorption and diffusion, which included 1)224Ra and226Ra desorption from sediments in water of different salinities, 2)224Ra and226Ra desorption from sediments of different grain sizes in water of the same salinity, 3)224Ra and226Ra diffusive fluxes by observing Ra enrichment with time in the overlying water of incubated sediments. The experimental results show that there is an increase in the amount of 224Ra and226Ra with the increase of salinity from 5 to 30, and Ra desorption is strongest at the salinity of 25. Under the same salt water condition,224Ra and226Ra desorption activities of the four grain sizes (2000~1000μm, 1000~500μm, 500~250μm and 250~125μm) of sediments are very close to each other. When the grain sizes of sediments are larger than 2000μm, the224Ra and226Ra desorption activities are slightly higher than those of the sediments of the above

  17. Sodium chloride, potassium chloride, and virulence in Listeria monocytogenes.

    OpenAIRE

    MYERS, E. R.; Dallmier, A W; Martin, S E

    1993-01-01

    Virulence, as determined in a mouse model, and the virulence factor activities of catalase, superoxide dismutase, and listeriolysin O were examined in a parental strain (10403S) and in a nonhemolytic mutant strain (DP-L224) of Listeria monocytogenes. The cells were propagated in media containing various concentrations of sodium chloride or potassium chloride. Strains 10403S and DP-L224 exhibited significant increases in catalase activity and listeriolysin O activity when grown in medium conta...

  18. AcEST: DK962436 [AcEST

    Lifescience Database Archive (English)

    Full Text Available xylase OS=Lithosperm... 224 2e-57 tr|Q0QDS3|Q0QDS3_9BORA Cinnamic acid 4-hydroxylase OS=Arnebia eu... 224 2e...W 555 W Sbjct: 150 W 150 >tr|Q0QDS3|Q0QDS3_9BORA Cinnamic acid 4-hydroxylase OS=Arnebia euchroma PE=2 SV=2 L

  19. National culture and business model change: a framework for successful expansions

    DEFF Research Database (Denmark)

    Dalby, J.; Nielsen, L.S.; Lueg, Rainer;

    2014-01-01

    Dalby, J., Nielsen, Lueg, R., L. S., Pedersen, L., Tomoni, A. C. 2014. National culture and business model change: a framework for successful expansions. Journal of Enterprising Culture, 22(4): 379-498.......Dalby, J., Nielsen, Lueg, R., L. S., Pedersen, L., Tomoni, A. C. 2014. National culture and business model change: a framework for successful expansions. Journal of Enterprising Culture, 22(4): 379-498....

  20. Minor Actinide Burning in Thermal Reactors. A Report by the Working Party on Scientific Issues of Reactor Systems

    International Nuclear Information System (INIS)

    The actinides (or actinoids) are those elements in the periodic table from actinium upwards. Uranium (U) and plutonium (Pu) are two of the principal elements in nuclear fuel that could be classed as major actinides. The minor actinides are normally taken to be the triad of neptunium (Np), americium (Am) and curium (Cm). The combined masses of the remaining actinides (i.e. actinium, thorium, protactinium, berkelium, californium, einsteinium and fermium) are small enough to be regarded as very minor trace contaminants in nuclear fuel. Those elements above uranium in the periodic table are known collectively as the transuranics (TRUs). The operation of a nuclear reactor produces large quantities of irradiated fuel (sometimes referred to as spent fuel), which is either stored prior to eventual deep geological disposal or reprocessed to enable actinide recycling. A modern light water reactor (LWR) of 1 GWe capacity will typically discharge about 20-25 tonnes of irradiated fuel per year of operation. About 93-94% of the mass of uranium oxide irradiated fuel is comprised of uranium (mostly 238U), with about 4-5% fission products and ∼1% plutonium. About 0.1-0.2% of the mass is comprised of neptunium, americium and curium. These latter elements accumulate in nuclear fuel because of neutron captures, and they contribute significantly to decay heat loading and neutron output, as well as to the overall radio-toxic hazard of spent fuel. Although the total minor actinide mass is relatively small - approximately 20-25 kg per year from a 1 GWe LWR - it has a disproportionate impact on spent fuel disposal, and thus the longstanding interest in transmuting these actinides either by fission (to fission products) or neutron capture in order to reduce their impact on the back end of the fuel cycle. The combined masses of the trace actinides actinium, thorium, protactinium, berkelium and californium in irradiated LWR fuel are only about 2 parts per billion, which is far too low for

  1. 肿瘤患者机体组成及肌肉减少症的调查%Observational research on body composition and sarcopenia in patients with tumor

    Institute of Scientific and Technical Information of China (English)

    吴焱; 凌轶群; 丁慧萍; 钱泳; 汪琼

    2016-01-01

    Objective:To observe body composition and the occurrence of sarcopenia in tumor patients so as to provide evidence for the early monitoring of their nutritional status .Methods:Bioelectrical impedance analysis(BIA) was adopted to analyze the body composition and appendicular skeletal muscle mass index (ASMI) was used to observe the occurrence of sarcopenia to explore the relationship between BMI and sarcopenia in 224 patients with tumor .The body composition of 224 cases of tumor patients was analyzed by bioelectrical impedance analysis(BIA) .The occurrence of sarcopenia was observed with appendicular skeletal mass index (ASMI) ,and the relationship between body mass index (BMI) and sarcopenia was also explored .Results:In 224 tumor patients ,13 .4% (30/224) were underweight ,60 .7% (136/224) were normal weight and 25 .9% (58/224) were overweight or obese .The incidence of sarcopenia was 58 .04% (130/224) ,and 77 .7% (101/130) of the patients with sarcopenia were normal ,overweight or obese .Conclusions:The change of the muscle and its function in cancer patients is as noteworthy as weight loss .Body composition of cancer patients should be timely monitored in order to optimize nutritional risk screening , establish individualized nutritional support , and develop the treatment plan with best tolerance .%目的:观察肿瘤患者的机体组成和肌肉减少症(sarcopenia)的发生情况,为尽早监测肿瘤患者的营养状况提供依据。方法:采用生物电阻抗法(bioelectrical impedance analysis ,BIA )分析224例肿瘤患者的机体组成,利用四肢骨骼肌指数(appendicular skeletal mass index ,ASMI)观察肌肉减少症的发生情况,并探究肿瘤患者体质指数(BMI)与肌肉减少症的关系。结果:224例肿瘤患者中13.4%(30/224)为消瘦,60.7%(136/224)为正常体质量,25.9%(58/224)为超重或肥胖。肌肉减少症发生率为58.04%(130/224) ,77.7

  2. Anabaena sp. DyP-type peroxidase is a tetramer consisting of two asymmetric dimers.

    Science.gov (United States)

    Yoshida, Toru; Ogola, Henry Joseph Oduor; Amano, Yoshimi; Hisabori, Toru; Ashida, Hiroyuki; Sawa, Yoshihiro; Tsuge, Hideaki; Sugano, Yasushi

    2016-01-01

    DyP-type peroxidases are a newly discovered family of heme peroxidases distributed from prokaryotes to eukaryotes. Recently, using a structure-based sequence alignment, we proposed the new classes, P, I and V, as substitutes for classes A, B, C, and D [Arch Biochem Biophys 2015;574:49-55]. Although many class V enzymes from eukaryotes have been characterized, only two from prokaryotes have been reported. Here, we show the crystal structure of one of these two enzymes, Anabaena sp. DyP-type peroxidase (AnaPX). AnaPX is tetramer formed from Cys224-Cys224 disulfide-linked dimers. The tetramer of wild-type AnaPX was stable at all salt concentrations tested. In contrast, the C224A mutant showed salt concentration-dependent oligomeric states: in 600 mM NaCl, it maintained a tetrameric structure, whereas in the absence of salt, it dissociated into monomers, leading to a reduction in thermostability. Although the tetramer exhibits non-crystallographic, 2-fold symmetry in the asymmetric unit, two subunits forming the Cys224-Cys224 disulfide-linked dimer are related by 165° rotation. This asymmetry creates an opening to cavities facing the inside of the tetramer, providing a pathway for hydrogen peroxide access. Finally, a phylogenetic analysis using structure-based sequence alignments showed that class V enzymes from prokaryotes, including AnaPX, are phylogenetically closely related to class V enzymes from eukaryotes.

  3. TRASH TO TREASURE: CONVERTING COLD WAR LEGACY WASTE INTO WEAPONS AGAINST CANCER

    International Nuclear Information System (INIS)

    As part of its commitment to clean up Cold War legacy sites, the U.S. Department of Energy (DOE) has initiated an exciting and unique project to dispose of its inventory of uranium-233 (233U) stored at Oak Ridge National Laboratory (ORNL), and extract isotopes that show great promise in the treatment of deadly cancers. In addition to increasing the supply of potentially useful medical isotopes, the project will rid DOE of a nuclear concern and cut surveillance and security costs. For more than 30 years, DOE's ORNL has stored over 1,200 containers of fissile 233U, originally produced for several defense-related projects, including a pilot study that looked at using 233U as a commercial reactor fuel. This uranium, designated as special nuclear material, requires expensive security, safety, and environmental controls. It has been stored at an ORNL facility, Building 3019A, that dates back to the Manhattan Project. Down-blending the material to a safer form, rather than continuing to store it, will eliminate a $15 million a year financial liability for the DOE and increase the supply of medical isotopes by 5,700 percent. During the down-blending process, thorium-229 (229Th) will be extracted. The thorium will then be used to extract actinium-225 (225Ac), which will ultimately supply its progeny, bismuth-213 (213Bi), for on-going cancer research. The research includes Phase II clinical trials for the treatment of acute myelogenous leukemia at Sloan-Kettering Memorial Cancer Center in New York, as well as other serious cancers of the lungs, pancreas, and kidneys using a technique known as alpha-particle radioimmunotherapy. Alpha-particle radioimmunotherapy is based on the emission of alpha particles by radionuclides. 213Bi is attached to a monoclonal antibody that targets specific cells. The bismuth then delivers a high-powered but short-range radiation dose, effectively killing the cancerous cells but sparing the surrounding tissue. Production of the actinium and

  4. TRASH TO TREASURE: CONVERTING COLD WAR LEGACY WASTE INTO WEAPONS AGAINST CANCER

    Energy Technology Data Exchange (ETDEWEB)

    Nicholas, R.G.; Lacy, N.H.; Butz, T.R.; Brandon, N.E.

    2004-10-06

    As part of its commitment to clean up Cold War legacy sites, the U.S. Department of Energy (DOE) has initiated an exciting and unique project to dispose of its inventory of uranium-233 (233U) stored at Oak Ridge National Laboratory (ORNL), and extract isotopes that show great promise in the treatment of deadly cancers. In addition to increasing the supply of potentially useful medical isotopes, the project will rid DOE of a nuclear concern and cut surveillance and security costs. For more than 30 years, DOE's ORNL has stored over 1,200 containers of fissile 233U, originally produced for several defense-related projects, including a pilot study that looked at using 233U as a commercial reactor fuel. This uranium, designated as special nuclear material, requires expensive security, safety, and environmental controls. It has been stored at an ORNL facility, Building 3019A, that dates back to the Manhattan Project. Down-blending the material to a safer form, rather than continuing to store it, will eliminate a $15 million a year financial liability for the DOE and increase the supply of medical isotopes by 5,700 percent. During the down-blending process, thorium-229 (229Th) will be extracted. The thorium will then be used to extract actinium-225 (225Ac), which will ultimately supply its progeny, bismuth-213 (213Bi), for on-going cancer research. The research includes Phase II clinical trials for the treatment of acute myelogenous leukemia at Sloan-Kettering Memorial Cancer Center in New York, as well as other serious cancers of the lungs, pancreas, and kidneys using a technique known as alpha-particle radioimmunotherapy. Alpha-particle radioimmunotherapy is based on the emission of alpha particles by radionuclides. 213Bi is attached to a monoclonal antibody that targets specific cells. The bismuth then delivers a high-powered but short-range radiation dose, effectively killing the cancerous cells but sparing the surrounding tissue. Production of the actinium and

  5. An alternative transformation in ranking using l_1 -norm in data envelopment analysis

    Science.gov (United States)

    Ziari, S.

    2016-05-01

    Jahanshahloo et al. (Appl Math Comput 153:215-224, 2004) propose a method for ranking extremely efficient decision making units (DMUs) in data envelopment analysis (DEA) using super-efficiency technique and l1-norm and they show that the presented method is able to eliminate the existing difficulties in some methods. This paper suggests an alternative transformation to convert the nonlinear model proposed by Jahanshahloo et al. (Appl Math Comput 153:215-224, 2004) into a linear programming form. The present paper shows that model with this transformation is equivalent to the above-mentioned nonlinear model. The motivation of this work is to linearize the proposed nonlinear model by Jahanshahloo et al. (Appl Math Comput 153:215-224, 2004) which has the higher order of complexity.

  6. Distribution Characteristics of Radium and Determination of Transport Rate in the Min River Estuary Mixing Zone%闽江河口区水体中镭的分布特征及河水与海水的混合速率

    Institute of Scientific and Technical Information of China (English)

    刘花台; 郭占荣; 高爱国; 袁晓婕; 李开培; 章斌; 马志勇

    2013-01-01

    The mixing between river water and seawater is a key interface process in the estuary.The mixing scale and rate concern the dispersion range and fate of the material transported by river.The aim of this paper is to calculate the transport rate of river plume in the estuary by using naturally occurring tracer 224 Ra and 226 Ra.In August 2010,we collected twenty groundwater samples,thirteen river water samples and twelve mixing samples in the estuary to measure the salinity,224 Ra and 226 Ra activities.The results showed that,1)224 Ra and 226 Ra activities in the groundwater samples were generally higher than those in the river water samples;2 )224 Ra activity was generally higher than 226 Ra activity in every sample;3)224 Ra activity largely increased when river water mixed with seawater,however,226 Ra activity increased slightly.Based on the differences of radioactive half-life between 224 Ra and 226 Ra,and only eddy diffusion mixture occurring between river water and seawater,the transport rate for river plume in the estuary was calculated to be 140.2 142.5 m/h.%入海河口中河水与海水的混合是海洋学中一个重要的界面过程,两者混合尺度和混合速率关系到河流携带物质的扩散范围和归宿,采用天然示踪剂224 Ra 和226 Ra 计算河水与海水的混合速率。2010年8月28日,采集了闽江河口区地下水样20个、河水样13个、河水与海水的混合水样12个,分别测量了每个水样的盐度、224 Ra 活度和226 Ra 活度。结果表明:地下水中224 Ra、226 Ra 活度普遍高于河水;所有水体中的224 Ra活度普遍都高于226 Ra 活度;河水遇到海水后,224 Ra 活度出现较大幅度的增加,而226 Ra 活度的增加并不明显。基于224 Ra 与226 Ra 半衰期的差异,在只有河水与海水发生涡流混合的情况下,计算获得河水与海水的混合速率为140.2~142.5 m/h。

  7. 利用STEP/XML的CAD/CAPP信息交换与共享模型及实现%The model of information exchange and sharing for CAD/CAPP using STEP and XML schema

    Institute of Scientific and Technical Information of China (English)

    陈守强; 蔡长韬

    2011-01-01

    针对异构系统之间难以解决的产品数据交换与共享问题,深入研究了制造信息资源共享、STEP AP203/AP214文件到AP224文件的转换规则等关键技术.采用STEP标准作为CAD系统的信息输出,提出了通过STEP中性文件转换器把CAD系统输出AP203/AP214文件转换成AP224文件,CAPP系统通过AP224中性文件来获取零件的几何和工艺信息的方法.利用STEP AP28所制定的转换规则,将STEP文件转换为相应的XML中性文件,建立XML schema库,以实现制造信息的数据交换和共享.%To solve the problem of product data exchange and sharing among heterogeneous systems, the key technologies, including manufacturing information sharing, file conversion from STEP AP203/AP214 to AP224 with the conversion ware of STEP neutral files, are discussed. Using STEP standard as information output of CAD systems, the AP203/AP214 file output from CAD systems is transformed to AP224 file with STEP neutral file, while CAPP systems obtained geometry and manufacturing process information of the parts with AP224 neutral files. By translating the STEP files into corresponding XML neutral files according to the transformation criterions constituted by STEP AP28, XML schema library is setup. Upon this, product data exchange and sharing of manufacturing information can be achieved.

  8. 胶州湾地区水体中镭同位素分布特征及其影响因素%Distribution characteristics of radium isotopes and their influence factors in the water of Jiaozhou Bay area

    Institute of Scientific and Technical Information of China (English)

    王博; 郭占荣; 袁晓婕; 章斌; 马志勇; 刘洁

    2014-01-01

    2012年4-5月以胶州湾地区为研究地点,分析和研究了该地区地下水、河水、海水中224Ra和226Ra的分布特征及其影响因素.结果表明,232Th和238U浓度较高的花岗岩地区地下水和河水中224Ra和226Ra的活度均比其他地区高;受到海水混合的影响,沿岸地区地下水和河水由于水体盐度升高,224Ra和226Ra从固体颗粒的解吸量增加,从而导致活度较高;受河流输入(溶解态和悬浮颗粒解吸)以及海底地下水排泄(Submarinegroundwater discharge,SGD)影响,胶州湾近岸海水224Ra活度相对较高,之后224Ra自身衰变以及外海水的混合稀释,使224Ra活度分布呈现随着离岸距离增加活度逐渐降低的特点;而226Ra活度在胶州湾内则保持一个较高水平,只出现个别226Ra低值分布区,主要原因是外海水与陆源淡水的226Ra活度较为接近且226Ra半衰期较长.

  9. Sequential phosphorylation of GRASP65 during mitotic Golgi disassembly

    Directory of Open Access Journals (Sweden)

    Danming Tang

    2012-09-01

    GRASP65 phosphorylation during mitosis and dephosphorylation after mitosis are required for Golgi disassembly and reassembly during the cell cycle. At least eight phosphorylation sites on GRASP65 have been identified, but whether they are modified in a coordinated fashion during mitosis is so far unknown. In this study, we raised phospho-specific antibodies that recognize phosphorylated T220/T224, S277 and S376 residues of GRASP65, respectively. Biochemical analysis showed that cdc2 phosphorylates all three sites, while plk1 enhances the phosphorylation. Microscopic studies using these antibodies for double and triple labeling demonstrate sequential phosphorylation and dephosphorylation during the cell cycle. S277 and S376 are phosphorylated from late G2 phase through metaphase until telophase when the new Golgi is reassembled. T220/224 is not modified until prophase, but is highly modified from prometaphase to anaphase. In metaphase, phospho-T220/224 signal localizes on both Golgi haze and mitotic Golgi clusters that represent dispersed Golgi vesicles and Golgi remnants, respectively, while phospho-S277 and S376 labeling is more concentrated on mitotic Golgi clusters. Expression of a phosphorylation-resistant GRASP65 mutant T220A/T224A inhibited mitotic Golgi fragmentation to a much larger extent than the expression of the S277A and S376A mutants. In cytokinesis, T220/224 dephosphorylation occurs prior to that of S277, but after S376. This study provides evidence that GRASP65 is sequentially phosphorylated and dephosphorylated during mitosis at different sites to orchestrate Golgi disassembly and reassembly during cell division, with phosphorylation of the T220/224 site being most critical in the process.

  10. Microstrip antenna for polarimetric C-band SAR

    DEFF Research Database (Denmark)

    Granholm, Johan; Woelders, Kim; Dich, Mikael;

    1994-01-01

    The paper outlines the design and the measured performance of a 224-element dual-linearly polarized microstrip array antenna with low cross-polarization. The array is currently being flown on the Danish high-resolution polarimetric C-band synthetic aperture radar (SAR)......The paper outlines the design and the measured performance of a 224-element dual-linearly polarized microstrip array antenna with low cross-polarization. The array is currently being flown on the Danish high-resolution polarimetric C-band synthetic aperture radar (SAR)...

  11. Design and adjustment of electric control system of motor car air conditioning and refrigeration system%动车空调制冷系统电气控制系统的设计与调试

    Institute of Scientific and Technical Information of China (English)

    潘洪坤

    2016-01-01

    基于动车空调制冷系统,提出来西门子CPU313、CPU226、CPU224、变频器、触摸屏及压缩机、冷风机和通风机组成主从控制系统。%Based onthe motor car air conditioning and refrigeration system,put forward the SIEMENS CPU313, CPU226,CPU224,inverter,touch screen and compressor, cold air fan and fan composed of master slave control system.

  12. Computed tomography studies of human brain movements

    International Nuclear Information System (INIS)

    Rhythmic brain movements have been revealed by sets of sequential computed tomography scans of human brains (seen retrospectively to be normal). These scans have shown that both (unenhanced) brain parenchymal density and the shapes of the elements of the supratentorial ventricular/cisternal system are subject to wave motions having similar periods - ranging from 26 s through 56 s, 77-96 s, 109 s and 224 s to 224 X 2 s (or even longer), with good correlation between peak values. These motions, as well as phase variations between the waves, suggest a peristaltic movement of cerebrospinal fluid through the ventricular/cisternal system with progressive axial damping

  13. Slow rhythmic ventricular oscillations and parenchymal density variations shown by sequential CT scanning

    International Nuclear Information System (INIS)

    Rhythmic brain movements have been revealed by sets of sequential computerised tomography scans of human brains (seen retrospectively to be normal). These scans have shown that both (unenhanced) brain parenchymal density and the shapes of the elements of the supratentorial ventricular/cisternal system are subject to wave motions having similar periods-ranging from 26 s through 56 s, 77-96 s, 109 s, and 224 s to 224 x 2 s (or even longer), with good correlation between peak values. These motions, as well as phase variations between the waves suggest a peristaltic movement of CSF through the ventricular/cisternal system with progressive axial damping

  14. 10 CFR Appendix A to Part 835 - Derived Air Concentrations (DAC) for Controlling Radiation Exposure to Workers at DOE Facilities

    Science.gov (United States)

    2010-01-01

    ...−08 - - 3 E+02 - - ET// Fr-223 4 E−07 - - 1 E+04 - - St// Ra-223 - 9 E−11 - - 3 E+00 - /St/ Ra-224 - 2 E−10 - - 8 E+00 - /St/ Ra-225 - 1 E−10 - - 4 E+00 - /St/ Ra-226 - 2 E−10 - - 9 E+00 - /St/ Ra-227 - 8 E−07 - - 3 E+04 - /BS/ Ra-228 - 1 E−10 - - 5 E+00 - /BS/ Ac-224 1 E−08 6 E−09 5 E−09 6 E+02 2...

  15. Well-defined 2:1 and 2:2 arylcopper-copper bromide aggregates and selective biaryl formation

    NARCIS (Netherlands)

    Koten, G. van; Janssen, M.D.; Corsten, M.A.; Spek, A.L.; Grove, D.M.

    1996-01-01

    Reaction of tetranuclear [Li4(C6H4CH2NMe2-2)4] (1) with 4/3 equiv of the copper(I) arenethiolate [Cu3(SC6H4NMe2-2)3] (2) results in the quantitative formation of the arylcopper compound [Cu4(C6H4CH2NMe2-2)4] (3) and the lithium arenethiolate [Li(SC6H4NMe2-2)]n (4). The arylcopper species 3 is a yell

  16. Alternating-parity collective states of yrast and nonyrast bands in lanthanide and actinide nuclei

    International Nuclear Information System (INIS)

    Excited collective states of even-even nuclei featuring quadrupole and octupole deformations are studied within a nonadiabatic collective model with a Gaussian potential energy. Rotational states of the yrast band and vibrational-rotational states of nonyrast bands are considered in detail. The energies of alternating-parity excited states of the yrast band in the 164Er, 220Ra, and 224Th nuclei; the yrast and first nonyrast bands in the 154Sm and 160Gd nuclei; and the yrast, first nonyrast, and second nonyrast bands in the 224Ra and 240Pu nuclei are described well on the basis of the proposed model

  17. A solid-state converter for measurement of aircraft noise and sonic boom

    Science.gov (United States)

    Zuckerwar, A. J.; Shope, W. W.

    1974-01-01

    A solid-state converter, used in a system of instrumentation for measuring aircraft noise and sonic boom, features a dual-gate FET mixer and an output stage designed for compatibility with a zero drive amplifier. With a half-inch condenser microphone the converter itself has an operating frequency range from dc-28 kHz (-3 dB), a dynamic range of 72 dB, and a noise floor of 50 dB in the band from 22.4 Hz to 22.4 kHz; the system requires no impedance matching networks and is insensitive to cable length up to at least 3000 ft.

  18. Formerly utilized MED/AEC sites remedial action program. Radiological survey of the E. I. Du Pont de Nemours and Co. , Deepwater, New Jersey. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-12-01

    The results of a radiological survey of the E. I. Du Pont Company, Deepwater, New Jersey, are presented in this report. During the 1940's this site was used for development of a process for the conversion of uranium oxide to produce uranium tetrafluoride and small quantities of uranium metal. The survey included measurements of the following: residual alpha and beta--gamma contamination levels, both fixed and transferable, in the one remaining uranium tetrafluoride operations building; external gamma radiation levels at 1 m above the surface inside this building and at outdoor locations where radioactive materials were handled; radon and radon daughter concentrations in the air in the operations building; uranium, radium, actinium, and thorium concentrations in soil and water on and near the site; and the airborne concentrations of uranium, thorium, and radium in the operations building. Elevated concentrations of uranium were found in residues from the operations building and in some surface and subsurface soil samples. Alpha and beta--gamma contamination levels in some areas of the operations building were above the limits of current federal guidelines set for the release of property for unrestricted use. 18 figures, 11 tables.

  19. Ac, La, and Ce radioimpurities in {sup 225}Ac produced in 40-200 MeV proton irradiations of thorium

    Energy Technology Data Exchange (ETDEWEB)

    Engle, Jonathan W.; Ballard, Beau D. [Los Alamos National Laboratory, NM (United States); Weidner, John W. [Air Force Institute of Technology, Wright Patterson Air Force Base, OH (United States); and others

    2014-10-01

    Accelerator production of {sup 225}Ac addresses the global supply deficiency currently inhibiting clinical trials from establishing {sup 225}Ac's therapeutic utility, provided that the accelerator product is of sufficient radionuclidic purity for patient use. Two proton activation experiments utilizing the stacked foil technique between 40 and 200 MeV were employed to study the likely co-formation of radionuclides expected to be especially challenging to separate from {sup 225}Ac. Foils were assayed by nondestructive γ-spectroscopy and by α-spectroscopy of chemically processed target material. Nuclear formation cross sections for the radionuclides {sup 226}Ac and {sup 227}Ac as well as lower lanthanide radioisotopes {sup 139}Ce, {sup 141}Ce, {sup 143}Ce, and {sup 140}La whose elemental ionic radii closely match that of actinium were measured and are reported. The predictions of the latest MCNP6 event generators are compared with measured data, as they permit estimation of the formation rates of other radionuclides whose decay emissions are not clearly discerned in the complex spectra collected from {sup 232}Th(p,x) fission product mixtures. (orig.)

  20. Pulse-shape discrimination and energy quenching of alpha particles in Cs$_2$LiLaBr$_6$:Ce$^{3+}$

    CERN Document Server

    Mesick, Katherine E; Stonehill, Laura C

    2016-01-01

    Cs$_2$LiLaBr$_6$:Ce$^{3+}$ (CLLB) is an elpasolite scintillator that offers excellent linearity and gamma-ray energy resolution and sensitivity to thermal neutrons with the ability to perform pulse-shape discrimination (PSD) to distinguish gammas and neutrons. Our investigation of CLLB has indicated the presence of intrinsic radioactive alpha background that we have determined to be from actinium contamination of the lanthanum component. We measured the pulse shapes for gamma, thermal neutron, and alpha events and determined that PSD can be performed to separate the alpha background with a moderate figure of merit of 0.98. We also measured the electron-equivalent-energy of the alpha particles in CLLB and simulated the intrinsic alpha background from $^{227}$Ac to determine the quenching factor of the alphas. A linear quenching relationship $L_{\\alpha} = E_{\\alpha} \\times q + L_0$ was found at alpha particle energies above 5 MeV, with a quenching factor $q = 0.71$ MeVee/MeV and an offset $L_0 = - 1.19$ MeVee.

  1. An Ion Exchange Study of Possible Hydridized 5f Bonding in theActinides

    Energy Technology Data Exchange (ETDEWEB)

    Diamond, R.M.; Street, Jr., K.; Seaborg, G.T.

    1951-08-28

    A study has been made of the elution behavior of curium(III), americium(III), plutonium(III), actinium(III), plutonium(IV), neptunium(IV), uraniuM(IV), thorium(IV), neptunium(V), plutonium (VI), uranium (VI), lanthanum(III), cerium(III), europium(III), ytterbium(III), ytterium(III), strontium(II), barium(II), radium(II), cesium(I) with 3.2 M, 6.2 M, 9.3 M, and 12.2 M HCl solutions from Dowex-50 cation exchange resin columns. These elutions show that in high concentrations of hydrochloric acid the actinides form complex ions with chloride ion to a much greater extent than the lanthanides. The strengths of the tripositive actinide complex ions apparently go in the order plutonium > americium> curium, although their ionic radii also decrease in this same order. To explain these results, a partial covalent character may be ascribed to the bonding in the transuranium complex ions. It is shown that a reasonable structure for such covalent bonding involves hybridization of the 5f orbitals in the actinide elements.

  2. Extending the north-east limit of the chart of nuclides

    CERN Document Server

    Benlliure, J; Kurtukian-Nieto, T; Schmidt, K -H; Audouin, L; Blank, B; Becker, F; Casarejos, E; Cortina-Gil, D; Enqvist, T; Fernández, B; Fernández-Ordóñez, M; Giovinazzo, J; Henzlova, D; Junghans, A R; Jurado, B; Napolitani, P; Pereira, J; Rejmund, F; Yordanov, O

    2010-01-01

    The existence of nuclei with exotic combinations of protons and neutrons provides fundamental information on the forces acting between nucleons. The maximum number of neutrons a given number of protons can bind, neutron drip line1, is only known for the lightest chemical elements, up to oxygen. For heavier elements, the larger its atomic number, the farther from this limit is the most neutron-rich known isotope. The properties of heavy neutron-rich nuclei also have a direct impact on understanding the observed abundances of chemical elements heavier than iron in our Universe. Above half of the abundances of these elements are thought to be produced in rapid-neutron capture reactions, r-process, taking place in violent stellar scenarios2 where heavy neutron-rich nuclei, far beyond the ones known up today, are produced. Here we present a major step forward in the production of heavy neutron-rich nuclei: the discovery of 73 new neutron-rich isotopes of chemical elements between tantalum (Z=72) and actinium (Z=89...

  3. Liquid Scintillation Counting of Environmental Radioisotopes: A Review of the Impact of Background Reduction

    Energy Technology Data Exchange (ETDEWEB)

    Douglas, Matthew; Bernacki, Bruce E.; Erchinger, Jennifer L.; Finn, Erin C.; Fuller, Erin S.; Hoppe, Eric W.; Keillor, Martin E.; Morley, Shannon M.; Mullen, Crystal A.; Orrell, John L.; Panisko, Mark E.; Warren, Glen A.; Wright, Michael E.

    2016-03-09

    Liquid scintillation counting (LSC) is a versatile and commonplace method for radiometric measurement of charged particle emitting radionuclides. The LSC method provides utility in a range of environmental science applications including hydrological studies of water transport, anthropogenic releases of radionuclides into the environment, and vertical mixing rates within oceans. Instrumental measurement background is one limiting factor of radiometric measurement sensitivity. As part of the development of a custom low background LSC system located in a shallow underground laboratory at Pacific Northwest National Laboratory, a number of measurement applications of LSC have been considered and are summarized here. The focus is on determining which aspects of such measurements would gain the greatest benefit from the reduction of LSC backgrounds by a factor of 10-100 relative to values reported in the literature. Examples of benefits include lowering the minimum detectable activity, reducing the sample size required, and shortening the elapsed timeline of the processing and analysis sequence. In particular tritium, strontium, and actinium isotopes are examined as these isotopes cover a range of requirements related to the LSC measurement method (e.g., 3H: low energy; Sr: spectral deconvolution; Ac: alpha/beta discrimination).

  4. Development of an Ultra-Low Background Liquid Scintillation Counter for Trace Level Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Erchinger, Jennifer L.; Orrell, John L.; Aalseth, Craig E.; Bernacki, Bruce E.; Douglas, Matthew; Finn, Erin C.; Fuller, Erin S.; Keillor, Martin E.; Morley, Shannon M.; Mullen, Crystal A.; Panisko, Mark E.; Shaff, Sarah M.; Warren, Glen A.; Wright, Michael E.

    2015-09-01

    Low-level liquid scintillation counting (LSC) has been established as one of the radiation detection techniques useful in elucidating environmental processes and environmental monitoring around nuclear facilities. The Ultra-Low Background Liquid Scintillation Counter (ULB-LSC) under construction in the Shallow Underground Laboratory at Pacific Northwest National Laboratory aims to further reduce the MDAs and/or required sample processing. Through layers of passive shielding in conjunction with an active veto and 30 meters water equivalent overburden, the background reduction is expected to be 10 to 100 times below typical analytic low-background liquid scintillation systems. Simulations have shown an expected background of around 14 counts per day. A novel approach to the light collection will use a coated hollow light guide cut into the inner copper shielding. Demonstration LSC measurements will show low-energy detection, spectral deconvolution, and alpha/beta discrimination capabilities, from trials with standards of tritium, strontium-90, and actinium-227, respectively. An overview of the system design and expected demonstration measurements will emphasize the potential applications of the ULB-LSC in environmental monitoring for treaty verification, reach-back sample analysis, and facility inspections.

  5. Purification of lanthanides for double beta decay experiments

    Energy Technology Data Exchange (ETDEWEB)

    Polischuk, O. G. [Institute for Nuclear Research, MSP 03680 Kyiv, Ukraine and INFN, Section of Rome, La Sapienza, I-00185 Rome (Italy); Barabash, A. S. [Institute of Theoretical and Experimental Physics, 117259 Moscow (Russian Federation); Belli, P. [INFN, Section of Rome Tor Vergata, I-00133 Rome (Italy); Bernabei, R. [INFN, Section of Rome Tor Vergata, I-00133 Rome, Italy and Department of Physics, University of Rome Tor Vergata, I-00133 Rome (Italy); Boiko, R. S.; Danevich, F. A.; Mokina, V. M.; Poda, D. V.; Tretyak, V. I. [Institute for Nuclear Research, MSP 03680 Kyiv (Ukraine); Cappella, F.; Incicchitti, A. [INFN, Section of Rome La Sapienza, I-00185 Rome, Italy and Department of Physics, University of Rome La Sapienza, I-00185 Rome (Italy); Cerulli, R.; Laubenstein, M.; Nisi, S. [INFN, Gran Sasso National Laboratories, I-67100 Assergi (Aq) (Italy)

    2013-08-08

    There are several potentially double beta active isotopes among the lanthanide elements. However, even high purity grade lanthanide compounds contain {sup 238}U, {sup 226}Ra and {sup 232,228}Th typically on the level of ∼ (0.1 - 1) Bq/kg. The liquid-liquid extraction technique was used to remove traces of U, Ra and Th from CeO{sub 2}, Nd{sub 2}O{sub 3} and Gd{sub 2}O{sub 3}. The radioactive contamination of the samples before and after the purification was tested by using ultra-low-background HPGe γ spectrometry at the underground Gran Sasso National Laboratories of the INFN (Italy). After the purification the radioactive contamination of gadolinium oxide by Ra and Th was decreased at least one order of magnitude. The efficiency of the approach to purify cerium oxide from Ra was on same level, while the radioactive contamination of neodymium sample before and after the purification is below the sensitivity of analytical methods. The purification method is much less efficient for chemically very similar radioactive elements like lanthanum, lutetium and actinium. R and D of the methods to remove the pollutions with improved efficiency is in progress.

  6. Soil and river sediments radionuclides monitoring at Aramar Experimental Center: an historical overview

    Energy Technology Data Exchange (ETDEWEB)

    Segre, Nadia; Fagundes, Rosane Correa, E-mail: nadia.segre@ctmsp.mar.mil.br [Centro Tecnologico da Marinha (CTM-SP/CEA/LARE), Ipero, SP (Brazil). Centro Experimental Aramar. Lab. Radioecologico; Moraes, Marco Antonio P.V. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2013-07-01

    In order to evaluate possible effects to the environment resulting from the implementation of the Centro Tecnologico da Marinha - Centro Experimental Aramar (CTMSP-CEA) at Ipero in Sao Paulo state, Brazil, which came into operation in 1989, an Environmental Monitoring Program (PMA) was established in October, 1987. One of the aims of this program is to monitor the soil and river sediments radionuclides levels at CEA and beyond its boundary. The utilization of statistical tools to evaluate the results of radiometric environmental monitoring is a procedure required by National Nuclear Energy Commission (CNEN). The box plot is a simple statistical tool for displaying data. The central tendency and dispersion of the results as well as the observation of unusual results (outliers) in the dataset are easily visualized. Control chart is a graph that maps data and provides a picture of how a process is performing over time. A control chart always has a central line for the mean, an upper line for the upper control limit and a lower line for the lower control limit. Box plots and control charts were used to visualize the annual amount of natural uranium, lead-214, actinium-228 and lead-212 in soil and river sediment detected between 1987 and 2011, considering the measurements of all monitored places each year. This historical observation shows that, in average, the results obtained are below than the 1987-1988 levels (CEA's pre-operational) or below than the backgrounds radionuclides values. (author)

  7. Background radiation and individual dosimetry in the costal area of Tamil Nadu, India.

    Science.gov (United States)

    Matsuda, Naoki; Brahmanandhan, G M; Yoshida, Masahiro; Takamura, Noboru; Suyama, Akihiko; Koguchi, Yasuhiro; Juto, Norimichi; Raj, Y Lenin; Winsley, Godwin; Selvasekarapandian, S

    2011-07-01

    South coast of India is known as the high-level background radiation area (HBRA) mainly due to beach sands that contain natural radionuclides as components of the mineral monazite. The rich deposit of monazite is unevenly distributed along the coastal belt of Tamil Nadu and Kerala. An HBRA site that laid in 2×7 m along the sea was found in the beach of Chinnavillai, Tamil Nadu, where the maximum ambient dose equivalent reached as high as 162.7 mSv y(-1). From the sands collected at the HBRA spot, the high-purity germanium semi-conductor detector identified six nuclides of thorium series, four nuclides of uranium series and two nuclides belonging to actinium series. The highest radioactivity observed was 43.7 Bq g(-1) of Th-228. The individual dose of five inhabitants in Chinnavillai, as measured by the radiophotoluminescence glass dosimetry system, demonstrated the average dose of 7.17 mSv y(-1) ranging from 2.79 to 14.17 mSv y(-1).

  8. DISSOLVED CONCENTRATION LIMITS OF RADIOACTIVE ELEMENTS

    Energy Technology Data Exchange (ETDEWEB)

    NA

    2004-11-22

    The purpose of this study is to evaluate dissolved concentration limits (also referred to as solubility limits) of elements with radioactive isotopes under probable repository conditions, based on geochemical modeling calculations using geochemical modeling tools, thermodynamic databases, field measurements, and laboratory experiments. The scope of this modeling activity is to predict dissolved concentrations or solubility limits for 14 elements with radioactive isotopes (actinium, americium, carbon, cesium, iodine, lead, neptunium, plutonium, protactinium, radium, strontium, technetium, thorium, and uranium) important to calculated dose. Model outputs for uranium, plutonium, neptunium, thorium, americium, and protactinium are in the form of tabulated functions with pH and log (line integral) CO{sub 2} as independent variables, plus one or more uncertainty terms. The solubility limits for the remaining elements are either in the form of distributions or single values. The output data from this report are fundamental inputs for Total System Performance Assessment for the License Application (TSPA-LA) to determine the estimated release of these elements from waste packages and the engineered barrier system. Consistent modeling approaches and environmental conditions were used to develop solubility models for all of the actinides. These models cover broad ranges of environmental conditions so that they are applicable to both waste packages and the invert. Uncertainties from thermodynamic data, water chemistry, temperature variation, and activity coefficients have been quantified or otherwise addressed.

  9. Tumor Immunotargeting Using Innovative Radionuclides

    Directory of Open Access Journals (Sweden)

    Françoise Kraeber-Bodéré

    2015-02-01

    Full Text Available This paper reviews some aspects and recent developments in the use of antibodies to target radionuclides for tumor imaging and therapy. While radiolabeled antibodies have been considered for many years in this context, only a few have reached the level of routine clinical use. However, alternative radionuclides, with more appropriate physical properties, such as lutetium-177 or copper-67, as well as alpha-emitting radionuclides, including astatine-211, bismuth-213, actinium-225, and others are currently reviving hopes in cancer treatments, both in hematological diseases and solid tumors. At the same time, PET imaging, with short-lived radionuclides, such as gallium-68, fluorine-18 or copper-64, or long half-life ones, particularly iodine-124 and zirconium-89 now offers new perspectives in immuno-specific phenotype tumor imaging. New antibody analogues and pretargeting strategies have also considerably improved the performances of tumor immunotargeting and completely renewed the interest in these approaches for imaging and therapy by providing theranostics, companion diagnostics and news tools to make personalized medicine a reality.

  10. Tumor immunotargeting using innovative radionuclides.

    Science.gov (United States)

    Kraeber-Bodéré, Françoise; Rousseau, Caroline; Bodet-Milin, Caroline; Mathieu, Cédric; Guérard, François; Frampas, Eric; Carlier, Thomas; Chouin, Nicolas; Haddad, Ferid; Chatal, Jean-François; Faivre-Chauvet, Alain; Chérel, Michel; Barbet, Jacques

    2015-01-01

    This paper reviews some aspects and recent developments in the use of antibodies to target radionuclides for tumor imaging and therapy. While radiolabeled antibodies have been considered for many years in this context, only a few have reached the level of routine clinical use. However, alternative radionuclides, with more appropriate physical properties, such as lutetium-177 or copper-67, as well as alpha-emitting radionuclides, including astatine-211, bismuth-213, actinium-225, and others are currently reviving hopes in cancer treatments, both in hematological diseases and solid tumors. At the same time, PET imaging, with short-lived radionuclides, such as gallium-68, fluorine-18 or copper-64, or long half-life ones, particularly iodine-124 and zirconium-89 now offers new perspectives in immuno-specific phenotype tumor imaging. New antibody analogues and pretargeting strategies have also considerably improved the performances of tumor immunotargeting and completely renewed the interest in these approaches for imaging and therapy by providing theranostics, companion diagnostics and news tools to make personalized medicine a reality. PMID:25679452

  11. Rutherford's curriculum vitae, 1894-1907.

    Science.gov (United States)

    Cohen, M

    1995-06-01

    A single page, handwritten document was discovered when the Macdonald Physics building of McGill University in Montreal was gutted in 1978. This proved to be the draft of Ernest Rutherford's curriculum vitae (C.V.) covering the years 1894-1907, probably written in the autumn of 1906 when Rutherford was preparing to leave McGill. The C.V. contains 21 headings in chronological order, referring to research and other activities of Rutherford and his coauthors (especially Soddy and Barnes), plus a further set of headings relating to the associated investigations of Rutherford's team, including Eve and Hahn. A transcript of the document is provided, although in several places, Rutherford's handwriting is difficult to interpret, and the significance of his abbreviations is not always clear. Each of the items in the C.V. is discussed briefly in this review, in the light both of Rutherford's personal career and of the contribution of his team to the development and understanding of radioactivity. This contribution included the cause and nature of radioactivity (with Soddy), energy aspects of radioactive decay (with Barnes), elucidation of the uranium-radium, thorium and actinium series (Godlewski and Hahn), the radioactivity of the earth and atmosphere (Eve), the nature of the gamma rays (Eve) and, perhaps most important of all, the nature and properties of the alpha particle (Rutherford himself). The latter investigations led directly to Rutherford's later work in Manchester, including the nuclear model of the atom and artificial disintegration of the nucleus.

  12. Data of evolutionary structure change: 1E4XH-1JGUH [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1E4XH-1JGUH 1E4X 1JGU H H QVQLQQPGAELVKPGASVKLSCKASGFTFTNYWMHWVKQ...EE EEE EEE EEEEEEEEEEE EEEEEEE EEEEEE --- 0... 1E4X H 1E4XHPHE CA 185 ARG CA 224 ILE CA 296 1E4X... H 1E4XH IGEILPSNGRT

  13. Simplified Classification of Focal Cortical Dysplasia

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2002-09-01

    Full Text Available Sections of cortex from 52 of 224 (23% patients with cortical dysplasia, operated on for drug-resistant partial epilepsy, were retrospectively re-examined histologically at Niguarda Hospital, and Istituto Nazionale Neurologico ‘C. Besta’, Milan, Italy.

  14. 77 FR 63877 - Notice of Quarterly Report (April 1, 2012-June 30, 2012)

    Science.gov (United States)

    2012-10-17

    ... transactions. Rural banks automated under the Automation/ Computerization and Interconnectivity of Rural Banks.... People trained (paralegal courses at Centre for Juridical and Judicial Training (CFJJ), general training... Smart Homes Activity. Wastewater Network Project....... $58,224,386 Improve the overall Sewer...

  15. Experiment list: SRX507394 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 361784: mutant PAS preincubation; Drosophila melanogaster; ChIP-Seq source_name=mutant_mutant_PAS preincubat...SRX507394 dm3 Input control Input control Adult Ovary NA 7228130,93.9,47.6,224 GSM1

  16. Multicultural Neuropsychology: Performance of Mandarin-Speaking Children On Widely Used Assessment Instruments

    Science.gov (United States)

    Hsieh, Shaio-Ling Judy; Tori, Christopher D.; Saito, Paul

    2008-01-01

    In order to extend the multicultural horizons of neuropsychological assessment in the Chinese mainland, a battery of eight commonly used neurocognitive tests assessing motor speed, verbal and visual-spatial memory, language fluency, attention, and executive functioning were given to 224 Mandarin-speaking school children (107 boys and 117 girls)…

  17. 敬赠读者超级享受(英文)

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    Badaling Wild Animals'WorldAdmission Ticket:RMB 90/per person¥50/per person(with this coupon)Date:April 1-December 31,2004Add:Beijing Badaling Great Wall Parking Lot(down from the 18th Exit if going along the Badaling Express Way)Tel:82087951,62014689,62015588-218,223,224,225)

  18. New genetic loci link adipose and insulin biology to body fat distribution

    DEFF Research Database (Denmark)

    Shungin, Dmitry; Winkler, Thomas W; Croteau-Chonka, Damien C.;

    2015-01-01

    -wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P

  19. Predictors of Academic Procrastination and University Life Satisfaction among Turkish Sport Schools Students

    Science.gov (United States)

    Ocal, Kubilay

    2016-01-01

    The purpose of this study was to examine the role of burnout, academic self-efficacy and academic success in predicting procrastination and university life satisfaction among sports schools students. The study sample comprised of 224 participants aged from 18 to 30 years with a mean age of 21.71 (SD = 1.94) who were attending various departments…

  20. Reduction in pedometer-determined physical activity in the adult Danish population from 2007 to 2012

    DEFF Research Database (Denmark)

    Matthiessen, Jeppe; Andersen, Elisabeth Wreford; Raustorp, Anders;

    2015-01-01

    Aims: To examine the development in pedometer-determined physical activity from 2007–2008 to 2011–2012 in the adult Danish population. Methods: The study population comprised two random samples of 18–75-year-old individuals who took part in cross-sectional studies in 2007–2008 (n=224) and 2011...

  1. Mobile location-based advertising: how information privacy concerns influence consumers' attitude and acceptance

    NARCIS (Netherlands)

    N. Limpf; H.A.M. Voorveld

    2015-01-01

    This study investigates the effect of information privacy concerns on consumers' attitude toward and acceptance of mobile location-based advertising (LBA), and the moderating role of the type of mobile LBA, namely push versus pull. Using an online experiment (N = 224), it was found that consumers' a

  2. Understanding Green Purchase Behavior: College Students and Socialization Agents

    Science.gov (United States)

    Yan, Ruoh-Nan; Xu, Huimin

    2010-01-01

    Taking the perspective of consumer socialization theory, this study examined the influences of different socialization agents on consumers' purchases of green products. A total of 224 surveys were distributed to students enrolled in a business-related course at a major university in the northeastern United States. The objectives were twofold. The…

  3. PCR screening for the surfactin (sfp) gene in marine Bacillus strains and its molecular characterization from Bacillus tequilensis NIOS11

    Digital Repository Service at National Institute of Oceanography (India)

    Porob, S.; Nayak, S.; Fernandes, Areena; Padmanabhan, P.; Patil, B.A.; Meena, R.M.; Ramaiah, N.

    reading frame of 675 bp coding for 224 amino acids with a theoretical molecular weight of 26,166.33 Da and a predicted isolectric point (pI) of 5.51. BLASTP analysis revealed 99% similarity to the earlier reported sfp gene of B. subtilis. Conserved domains...

  4. Gut fluorescence analysis of barnacle larvae: An approach to quantify the ingested food

    Digital Repository Service at National Institute of Oceanography (India)

    Gaonkar, C.A.; Anil, A.C.

    pellets it was 224(plus or minus 63) ng chlorophyll a larva sup(−1). A phaeopigment concentration in larval gut was found to be 311(plus or minus 13) ng larva sup(−1) and in faecal pellets it was 172(plus or minus 61) ng larva sup(−1). The study also...

  5. Hydrochemical studies along the coastal waters off Mangalore

    Digital Repository Service at National Institute of Oceanography (India)

    Joseph, T.; Balachandran, K.K.; Nair, M.; Sankaranarayanan, V.N.

    Mangaloe port to Surathkal were monitored biomonthly and different parameters were compared seasonwise. Inorganic phosphate values registered high values at all the transects during September, with a maximum of 2.24 mu mol/l. Nitrite was found to be absent...

  6. Westerbork Ultra-Deep Survey of HI at z=0.2

    NARCIS (Netherlands)

    Verheijen, Marc; Deshev, Boris; van Gorkom, Jacqueline; Poggianti, Bianca; Chung, Aeree; Cybulski, Ryan; Dwarakanath, K. S.; Montero-Castano, Maria; Morrison, Glenn; Schiminovich, David; Szomoru, Arpad; Yun, Min

    2010-01-01

    In this contribution, we present some preliminary observational results from the completed ultra-deep survey of 21cm emission from neutral hydrogen at redshifts z=0.164-0.224 with the Westerbork Synthesis Radio Telescope. In two separate fields, a total of 160 individual galaxies has been detected i

  7. 49 CFR 571.223 - Standard No. 223; Rear impact guards.

    Science.gov (United States)

    2010-10-01

    ... forward of the vehicle's rear extremity, as defined in S4 of 49 CFR 571.224, Rear Impact Protection. See... Motor Vehicle Safety Standards § 571.223 Standard No. 223; Rear impact guards. S1. Scope. This standard... vehicles collide with the rear end of trailers and semitrailers. S3. Application. This standard applies...

  8. Computerized and Paper-and-Pencil Versions of the Rosenberg Self-Esteem Scale: A Comparison of Psychometric Features and Respondent Preferences.

    Science.gov (United States)

    Vispoel, Walter P.; Boo, Jaeyool; Bleiler, Timothy

    2001-01-01

    Evaluated the characteristics of computerized and paper-and-pencil versions of the Rosenberg Self-Esteem Scale (SES) using scores for 224 college students. Results show that mode of administration has little effect on the psychometric properties of the SES although the computerized version took longer and was preferred by examinees. (SLD)

  9. Gallegos and Kyle: Five Thousand Years of Maritime Subsistence at CA-SDI-48, on Ballast Point, San Diego County, California

    OpenAIRE

    Warren, Claude N.

    2007-01-01

    Five Thousand Years of Maritime Subsistence at CA-SDI-48, on Ballast Point, San Diego County, California. Dennis Gallegos and Carolyn Kyle. Salinas: Coyote Press, 1998. [Archives of California Prehistory No. 40.] Xiv + 224 pp., 32 figs., 86 tables, 1 appendix. $23.00, (paper).

  10. A theoretical analysis of how segmentation of dynamic visualizations optimizes students' learning

    NARCIS (Netherlands)

    Spanjers, Ingrid; Van Gog, Tamara; Van Merriënboer, Jeroen

    2010-01-01

    Spanjers, I. A. E., Van Gog, T., & Van Merriënboer, J. J. G. (2010). A theoretical analysis of how segmentation of dynamic visualizations optimizes students’ learning. Educational Psychology Review, 22(4), 411-423. doi:10.1007/s10648-010-9135-6

  11. 77 FR 6853 - Agency Information Collection Activities: Proposed Request and Comment Request

    Science.gov (United States)

    2012-02-09

    ... Retirement, Survivors, Disability, and Health Insurance benefits. Type of Request: Revision of an OMB... 224 of the Social Security Act provides for the reduction of disability insurance benefits (DIB) when... Reconsideration--Disability Cessation--20 CFR 404.909, 416.1409--0960-0349. SSA uses Form SSA-789-U4 to...

  12. Euroopa Liidu õigusest tulenevad võimalused jõustunud kohtuotsuste ja haldusaktide uueks läbivaatamiseks / Piret Schasmin, Carri Ginter

    Index Scriptorium Estoniae

    Schasmin, Piret

    2015-01-01

    Vastuoludest õiguskindluse ning kohustuse vahel tagamaks Euroopa Liidu õiguse tõhus ja ühetaoline kohaldamine. Euroopa Kohtu lahenditest (C-553/13, C-224/97, C-453/00, C-2/06, C-110/99) ja Eesti kohtupraktikast

  13. Parents' Attitudes and Expectations about Children's Cross-Gender Behavior.

    Science.gov (United States)

    Sandnabba, N. Kenneth; Ahlberg, Christian

    1999-01-01

    Assessed parents' attitudes toward cross-gender behavior of boys and girls. Responses of 224 white Finnish parents of 5-year olds reveal that cross-gender boys are regarded more negatively than cross-gender girls. Men perceived more societal acceptance of cross-gender boys than did women. It is thought that cross-gender boys were more likely to…

  14. Strichartz Estimates for the Schrödinger Propagator for the Laguerre Operator

    Indian Academy of Sciences (India)

    Vijay Kumar Sohani

    2013-11-01

    We obtain homogeneous Strichartz estimate for the Schrödinger propagator $e^{-itL_}$ for the Laguerre operator $L_$ on $\\mathbb{R}^n_+$. We follow regularization technique as introduced in J. Funct. Anal. 224(2) (2005) 371–385. We also establish inhomogeneous Strichartz estimates for different admissible pairs.

  15. Gclust Server: 177175 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 177175 CRE_190493 Cluster Sequences - 224 no annotation 1 1.00e-99 14.29 0.0 0.0 0.0 0.0 0.0 Show 17717...5 Cluster ID 177175 Sequence ID CRE_190493 Link to cluster sequences Cluster Sequences L

  16. Microstrip antenna for polarimetric C-band SAR

    OpenAIRE

    Granholm, Johan; Woelders, Kim; Dich, Mikael; Christensen, Erik Lintz

    1994-01-01

    The paper outlines the design and the measured performance of a 224-element dual-linearly polarized microstrip array antenna with low cross-polarization. The array is currently being flown on the Danish high-resolution polarimetric C-band synthetic aperture radar (SAR)

  17. Parametrization of cosets for AdS5xS5 superstring action

    CERN Document Server

    Siegel, W

    2015-01-01

    A formulation recently proposed [arXiv:1506.07706] as an alternative to the usual coset PSU(2,2|4)/USp(2,2)USp(4) for the superspace geometry of the Type IIB superstring on an AdS5xS5 background is shown to be a particular parametrization of this coset. Standard methods can then be applied.

  18. Developmentally Disabled Persons in Family Settings: Report No. 2.

    Science.gov (United States)

    Cox, Wendy M.; Wilson, Wendell L.

    The second in a series of three reports, this document presents findings of clients of Washington's Division of Developmental Disabilities (DDD), ages 22-29, who were living with their families at age 18 but now live elsewhere (group B). Findings are based on telephone interviews with families of 224 DDD clients and analysis of DDD records. The…

  19. Sex Differences in Emotional and Behavioral Responses to HIV+ individuals’ Expression of Distress

    NARCIS (Netherlands)

    A.E.R. Bos (Arjan); A.J. Dijker (Anton); W. Koomen

    2007-01-01

    textabstractTwo studies examined the influence of HIV+ individual’s expression of distress on perceivers’ emotional and behavioral reactions. In Study 1 (N = 224), HIV+ individuals’ expression of distress was experimentally manipulated by means of vignettes. Men and women reacted differently when pe

  20. The association of duration of hypertension and changes in cognitive function in hypertension patients

    Institute of Scientific and Technical Information of China (English)

    李拓

    2014-01-01

    Objective To investigate the relationship between duration of hypertension and cognitive function in adult hypertension patients.Methods A total of 224 subjects with normal blood pressure were enrolled in group A,and 1 296 patients with poorly controlled hypertension were further divided by the duration of hypertension into

  1. Do People “Like” Politicians on Facebook? Not really

    DEFF Research Database (Denmark)

    Nielsen, Rasmus Kleis; Cristian, Vaccari

    2013-01-01

    The online popularity of a few exceptional candidates has led many to suggest that social media have given politicians powerful new ways of communicating directly with voters. Examining whether this is happening on a significant scale, we find that, based on analysis of 224 major party candidates...

  2. Festivalipäevik Kanutist II / Anu Allas, Margit Tõnson, Margaret Tali

    Index Scriptorium Estoniae

    Allas, Anu, 1977-

    2005-01-01

    Tallinnas Kanuti Gildi saalis kestab 2.-24. novembrini 2005 a. "Continental Breakfast" Tallinn ehk rahvusvaheline NU Performance festival. 9. novembril esineb BabaLAN (Vlado Gotvan Repnik, Sloveenia ) multimeedia-performance'iga. Eva Meyer Kelleri performance "Surm on kindel" (esitaja Irina Müller)

  3. Why Koreans are More Likely to Favor "Apology," While Americans are More Likely to Favor "Thank You"

    Science.gov (United States)

    Lee, Hye Eun; Park, Hee Sun

    2011-01-01

    Two studies investigated whether apologies or thanks are preferred in asking favors in the United States and Korea, and how this relates to perceptions of reduction in positive and negative face threats. In the first study (n = 224), participants composed an e-mail message where a favor was asked. In the second (n = 807), participants completed…

  4. An expedient and new synthesis of pyrrolo[1,2-b]pyridazine derivatives

    Directory of Open Access Journals (Sweden)

    Rajeshwar Reddy Sagyam

    2009-11-01

    Full Text Available The reaction of 2-[2-(4-fluorophenyl-2-oxo-1-phenylethyl]-4-methyl-3-oxo-pentanoic acid phenylamide with tertiary butyl carbazate and subsequent condensation of the resulting carbamate derivative with a chalcone provided a facile new approach to pyrrolo[1,2-b]pyridazine derivatives.

  5. Dicty_cDB: Contig-U14955-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available mpling_GS-30-02-01-1... 50 2e-06 3 ( EU111781 ) Bartonella coopersplainensis strain AUST/NH20 cel... 40 3e-0...3 |pid:none) Myxococcus xanthus DK 1622, com... 224 4e-57 EU111781_1( EU111781 |pid:none) Bartonella coope

  6. Blurring the Line between Researcher and Researched in Interview Studies: A Feminist Practice?

    Science.gov (United States)

    Yost, Megan R.; Chmielewski, Jennifer F.

    2013-01-01

    This commentary is intended to serve as a companion to the authors' original research article ("Psychosocial Influences on Bisexual Women's Body Image Negotiating Gender and Sexuality," "Psychology of Women Quarterly," v37 n2 p224-241 Jun 2013) and to contribute to the conversation on feminist research methods. In it,…

  7. VizieR Online Data Catalog: Evolution of long-lived globular cluster stars (Chantereau+ 2016)

    Science.gov (United States)

    Chantereau, W.; Charbonnel, C.; Meynet, G.

    2016-08-01

    We present a grid of 224 stellar evolution models for low-mass stars with initial masses between 0.3 and 1.0Mȯ and initial helium mass fraction between 0.248 and 0.8 computed for [Fe/H]=-1.75 with the stellar evolution code STAREVOL. (2 data files).

  8. Gender Differences in the Perceived Severity of Boot Camp

    Science.gov (United States)

    Wood, Peter B.; May, David C.; Grasmick, Harold G.

    2005-01-01

    We analyze survey data from 181 male and 224 female inmates serving brief prison terms for nonviolent offenses to examine offenders' perceptions of the severity of boot camp compared to prison. Building on the limited work in this area, we present reasons those offenders feel are important to both avoid and participate in alternative sanctions.…

  9. Testing of PCM Heat Storage Modules with Solar Collectors as Heat Source

    DEFF Research Database (Denmark)

    Englmair, Gerald; Dannemand, Mark; Johansen, Jakob Berg;

    2016-01-01

    was to actively utilize the ability of the material to supercool to obtain long storage periods. The modules were charged with solar heat supplied by 22.4 m2 evacuated tubular collectors. The investigation showed that it was possible to fully charge one module within a period of 270 minutes with clear skies...

  10. 78 FR 10160 - Notice of Commission Meeting and Public Hearing

    Science.gov (United States)

    2013-02-13

    ..., at paula.schmitt@drbc.state.nj.us or by phoning Ms. Schmitt at 609-883- 9500 ext. 224. Addresses for... should contact the Commission Secretary directly at 609-883- 9500 ext. 203 or through the... examined at the Commission's offices by appointment by contacting Carol Adamovic, 609-883-9500, ext....

  11. 78 FR 70544 - Notice of Public Hearing and Business Meeting

    Science.gov (United States)

    2013-11-26

    .... Schmitt at 609-883- 9500 ext. 224. Addresses for Written Comment. Written comment on items scheduled for... Commission Secretary directly at 609-883- 9500 ext. 203 or through the Telecommunications Relay Services (TRS... Commission's offices by appointment by contacting Carol Adamovic, 609-883-9500, ext. 249. For other...

  12. 78 FR 54244 - Notice of Public Hearing and Business Meeting

    Science.gov (United States)

    2013-09-03

    ... phoning Ms. Schmitt at 609-883- 9500 ext. 224. Addresses for Written Comment. Written comment on items..., conference session or hearings should contact the Commission Secretary directly at 609-883- 9500 ext. 203 or... Adamovic, 609-883-9500, ext. 249. For other questions concerning hearing items, please contact...

  13. Interracial and Intraracial Contact, School-Level Diversity, and Change in Racial Identity Status among African American Adolescents

    Science.gov (United States)

    Yip, Tiffany; Seaton, Eleanor K.; Sellers, Robert M.

    2010-01-01

    Among 224 African American adolescents (mean age = 14), the associations between interracial and intraracial contact and school-level diversity on changes in racial identity over a 3-year period were examined. Youths were determined to be diffused, foreclosed, moratorium, or achieved, and change or stability in identity status was examined.…

  14. IonCCD Detector for Miniature Sector-Field Mass Spectrometer : Investigation of Peak Shape and Detector Surface Artifacts Induced by keV Ion Detection

    NARCIS (Netherlands)

    Hadjar, Omar; Schlatholter, Thomas; Davila, Stephen; Catledge, Shane A.; Kuhn, Ken; Kassan, Scott; Kibelka, Gottfried; Cameron, Chad; Verbeck, Guido F.

    2011-01-01

    A recently described ion charge coupled device detector IonCCD (Sinha and Wadsworth, Rev. Sci. Instrum. 76(2), 2005; Hadjar, J. Am. Soc. Mass Spectrom. 22(4), 612-624, 2011) is implemented in a miniature mass spectrometer of sector-field instrument type and Mattauch-Herzog (MH)-geometry (Rev. Sci. I

  15. La participación de las familias en la educación escolar. Mirando al futuro [RECENSIÓN

    OpenAIRE

    Rivas-Borrell, S. (Sonia)

    2015-01-01

    Recensión de Ministerio de Educación, Cultura y Deporte (2014). La participación de las familias en la educación escolar. Mirando al futuro. Madrid: Secretaría General Técnica. Subdirección General de Documentación y Publicaciones, 224 pp.

  16. Reference: GLUTAACAOS [PLACE

    Lifescience Database Archive (English)

    Full Text Available GLUTAACAOS Takaiwa F, Oono K Interaction of an immature seed-specific trans-acting ...factor with the 5' upstream region of a rice glutelin gene. Mol Gen Genet 224:289-293 (1990) PubMed: 2277646; ...

  17. 40 CFR Appendix G to Part 75 - Determination of CO2 Emissions

    Science.gov (United States)

    2010-07-01

    ... company records, tons/day. 2.2.4The daily CO2 mass emissions from combusting coal may be adjusted to... monitoring system (consisting of an SO2 pollutant concentration monitor and an O2 or CO2 diluent gas monitor... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Determination of CO2 Emissions...

  18. Determination and Interpretation of the Norm Values of Preschool Social Skills Rating Scale Teacher Form

    Science.gov (United States)

    Omeroglu, Esra; Buyukozturk, Sener; Aydogan, Yasemin; Cakan, Mehtap; Cakmak, Ebru Kilic; Ozyurek, Arzu; Akduman, Gulumser Gultekin; Gunindi, Yunus; Kutlu, Omer; Coban, Aysel; Yurt, Ozlem; Kogar, Hakan; Karayol, Seda

    2015-01-01

    This study aimed to determine and interpret norms of the Preschool Social Skills Rating Scale (PSSRS) teacher form. The sample included 224 independent preschools and 169 primary schools. The schools are distributed among 48 provinces and 3324 children were included. Data were obtained from the PSSRS teacher form. The validity and reliability…

  19. Social Skills Expression of Senior High School Age Students in Physical Education Classes

    Science.gov (United States)

    Akelaitis, Arturas V.

    2015-01-01

    The main purpose of the present study is to reveal the peculiarities of social skills expression of senior high school age students in physical education classes. The independent random sample consisted of 244 (15-16 years old) students and 258 (17-18 years old) students, of which there were 224 boys and 278 girls. L. Bulotaite and V. Gudžinskiene…

  20. Vereenvoudiging van het Welfare Quality protocol voor vleeskalveren

    NARCIS (Netherlands)

    Reenen, van C.G.; Vereijken, P.F.G.; Buist, W.G.; Thissen, J.T.N.M.; Engel, B.

    2012-01-01

    In dit rapport wordt de resultaten beschreven van onderzoek naar mogelijkheden om het Welfare Quality® protocol voor het beoordelen van welzijn van vleeskalveren te vereenvoudigen. Uitgangspunt voor het vereenvoudingsonderzoek was een data-set met waarnemingen aan vleeskalveren op in totaal 224 vlee

  1. Post-Qualifying Practice for Mental Health Social Workers

    OpenAIRE

    Campbell, Jim; Davidson, Gavin

    2012-01-01

    Sign In Bookmark and Share Post-Qualifying Mental Health Social Work Practice Jim Campbell Goldsmiths, University of London Gavin Davidson Queen's University Belfast © 2012 224 pages SAGE Publications Ltd Lecturers Inspection Copy Individual Purchasers Paperback ISBN: 9781848609952 £24.99 Hardcover ISBN: 9781848609945 £69.00 Ebook ISBN: 9781446258699 Other Titles in: Mental Health Policy | Social Work Practice About...

  2. Propargylamine-isothiocyanate reaction: efficient conjugation chemistry in aqueous media

    DEFF Research Database (Denmark)

    Viart, Helene Marie-France; Larsen, T. S.; Tassone, Chiara;

    2014-01-01

    A coupling reaction between secondary propargyl amines and isothiocyanates in aqueous media is described. The reaction is high-yielding and affords cyclized products within 2-24 h. A functionalized ether lipid was synthesized in 8 steps, formulated as liposomes with POPC and conjugated to FITC un...

  3. Derivation of heat value of coke/char from proximate analysis

    Energy Technology Data Exchange (ETDEWEB)

    Roy, R.R.P. (and others)

    From experimental data on high-, medium- and low-temperature cokes or chars, the following formulae were derived: gross CV (kcal/kg) 80(FC) + 76(VM); hydrogen content 0.224(VM). All values are on the air-dried basis.

  4. Primary School Text Comprehension Predicts Mathematical Word Problem-Solving Skills in Secondary School

    Science.gov (United States)

    Björn, Piia Maria; Aunola, Kaisa; Nurmi, Jari-Erik

    2016-01-01

    This longitudinal study aimed to investigate the extent to which primary school text comprehension predicts mathematical word problem-solving skills in secondary school among Finnish students. The participants were 224 fourth graders (9-10 years old at the baseline). The children's text-reading fluency, text comprehension and basic calculation…

  5. Perceived Support as a Predictor of Acculturative Stress among International Students in the United States

    Science.gov (United States)

    Bai, Jieru

    2016-01-01

    A quantitative study was conducted to measure the acculturative stress of international students and investigate the predictors of acculturative stress. A total of 186 students participated in the survey. Results showed that 22.4% of the students in this study exceeded the normal stress level and might need counseling or psychological…

  6. A Multi-Dimensional Model of the Origins of Attitude Certainty: Teachers' Attitudes toward Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Anderson, Donnah L.; Watt, Susan E.; Shanley, Dianne C.

    2014-01-01

    This research tested and extended a laboratory-derived model of the origins of attitude certainty using a real attitude object: Teaching children with attention-deficit/hyperactivity disorder (ADHD). In Study 1, an experiment manipulated the amount of information, thought, and consistency of information delivered to pre-service teachers (n = 224)…

  7. Soil test and bermudagrass forage yield responses to animal waste and FGD gypsum ammendments

    Science.gov (United States)

    Knowledge of soil and plant responses to animal or industrial byproducts is needed for effective use of these potential amendments on reclaimed mine soil. This study compared seven treatments of 11.2 Mg ha-1 flue gas desulfurized (FGD) gypsum (control), 896 kg ha-1 NPK fertilizer (13-13-13), 22.4 M...

  8. Qualification and Gender Dimensions in Attitude of Secondary School Social Studies Teachers towards Computer Usage in Kogi State Nigeria

    Science.gov (United States)

    Achor, Emmanuel E.; Shaibu, Joshua S.

    2013-01-01

    This study examined attitude dimensions of secondary school social studies teachers towards computer usage in Kogi State Nigeria. Qualification and Gender influence on their use was examined. Participants were 427 (Male = 224; female = 203) social studies teachers. Sampling was purposive and random. The study adopted the survey design. Data were…

  9. Mediators of Telephone-Based Continuing Care for Alcohol and Cocaine Dependence

    Science.gov (United States)

    Mensinger, Janell Lynn; Lynch, Kevin G.; Tenhave, Thomas R.; McKay, James R.

    2007-01-01

    A previous randomized trial with 224 alcohol and/or cocaine addicts who had completed an initial phase of treatment indicated that 12 weeks of telephone-based continuing care yielded higher abstinence rates over 24 months than did group counseling continuing care. The current study examined mediators of this treatment effect. Results suggested…

  10. The semi-classical energy of closed Nambu-Goto strings

    CERN Document Server

    Zahn, Jochen

    2016-01-01

    We compute semi-classical corrections to the energy of rotating closed Nambu-Goto strings. We find the Regge intercept $a = 1 + \\frac{D-2}{24}$ for $D$ dimensional target space. Also the discrepancy with the standard approaches to string quantization is clarified.

  11. Design,Synthesis and Antifungal Activity of Novel Triazole Derivatives

    Institute of Scientific and Technical Information of China (English)

    Chun Quan SHENG; Wan Nian ZHANG; Hai Tao JI; Yun Long SONG; Min ZHANG; You Jun ZHOU; Jia Guo LU; Jü ZHU

    2004-01-01

    Twenty-one 1-(1H-1,2,4-triazolyl)-2-(2,4-diflurophenyl)-3-(4-substituted-1- piperazinyl)-2-propanol derivatives were designed and synthesized,on the basis of the active site of lanosterol 14(-demethylase.In vitro antifungal activities showed that some of the target compounds had higher antifungal activity and broader antifungal spectrum than fluconazole.

  12. Multiphosphine-Oxide Hosts for Ultralow-Voltage-Driven True-Blue Thermally Activated Delayed Fluorescence Diodes with External Quantum Efficiency beyond 20.

    Science.gov (United States)

    Zhang, Jing; Ding, Dongxue; Wei, Ying; Han, Fuquan; Xu, Hui; Huang, Wei

    2016-01-20

    Highly efficient low-voltage-driven -true-blue thermally activated -delayed fluorescence diodes are realized through employing a tri-phosphine oxide host (2,2',4-tris(di(phenyl) -phosphoryl)-diphenylether (DPETPO)) with a record external quantum efficiency of 23.0% and the lowest onset voltage of 2.8 V to date.

  13. 76 FR 54289 - Petition for Waiver of Compliance

    Science.gov (United States)

    2011-08-31

    ... restricted freight cars; and Reflectorization of Rail Freight Rolling Stock, 49 CFR 224.101, which requires the application of reflective materials for freight rolling stock. FWRY requests this relief for five... stenciling location of the reporting marks and built date from each side of the freight carbody (49 CFR...

  14. AcEST: BP921281 [AcEST

    Lifescience Database Archive (English)

    Full Text Available synthase OS=Calystegia hederacea PE=2 SV=1 Length = 520 Score = 224 bits (571), ...AAC +VP+TI D Sbjct: 481 HRMAMAFSLAACSDVPVTIKD 501 >tr|B2CM20|B2CM20_9ASTE 5-enolpyruvylshikimate 3-phosphate

  15. Breeding of an anti-postacidification strain from Lactobacillus bulgaricus by NTG mutagenesis%抗后酸化保加利亚乳杆菌的亚硝基胍诱变选育

    Institute of Scientific and Technical Information of China (English)

    车黎猛; 任发政; 张恒涛; 常征; 蔡华伟

    2006-01-01

    利用0.9mg/mL亚硝基胍对保加利亚乳杆菌ZLB进行诱变处理30min(菌株致死率为99%),中间培养后用青霉素筛选.处理液涂布培养后,选取生长缓慢或不长的32株接种于RSM(Reconstituted Skimmed Milk)培养基中,随后选取凝固的16株做12℃贮藏,最终得到产酸较慢的突变株ZT224、ZT227.突变株与ZLB相比,在42℃时,ZT224、ZT227在RSM培养基中滴定酸度值明显减少.发酵脱脂乳在12℃贮藏时,ZT224的发酵乳在贮藏的20d内一直没有发生后酸化;ZT227发生后酸化的时间推迟了4d.同时,突变株ZT224、ZT227对链霉素的敏感性不同于出发菌株ZLB且能稳定遗传.

  16. The Investigation on Critical Thinking Ability in EFL Reading Class

    Science.gov (United States)

    Zhou, Jie; Jiang, Yuhong; Yao, Yuan

    2015-01-01

    The present mixed-method study aims to find out the status quo of critical thinking ability of university non-English majors by investigating 224 non-English majors from a university in China (105 male and 119 female students, 114 art and 110 science majors, 109 freshmen and 115 sophomores were included respectively) through questionnaires and…

  17. Defendants with Intellectual Disabilities and Mental Health Diagnoses: Faring in a Mental Health Court

    Science.gov (United States)

    Burke, M. M.; Griggs, M.; Dykens, E. M.; Hodapp, R. M.

    2012-01-01

    Background: Begun in the late 1990s, mental health courts are specialty criminal courts developed to address the needs of persons with mental illness. Methods: As many persons with intellectual disabilities (IDs) may overlap in the mental health court system, we used mental health court records to examine the phenomenology and outcomes of 224

  18. Testing Three Explanations of the Emergence of Weapon Carrying in Peer Context: The Roles of Aggression, Victimization, and the Social Network

    NARCIS (Netherlands)

    Dijkstra, J.K.; Gest, S.D.; Lindenberg, S.M.; Veenstra, D.R.; Cillessen, A.H.N.

    2012-01-01

    Purpose: To examine the relative contribution of weapon carrying of peers, aggression, and victimization to weapon carrying of male and female adolescents over time. Methods: Data were derived from a population-based sample of male (N = 224) and female (N = 244) adolescents followed from grade 10 (M

  19. Gender Differences and E-commerce Behavior and Perceptions

    OpenAIRE

    Kurt Schimmel,DBA; Jeananne Nicholls

    2003-01-01

    This paper examines the existence of gender differences regarding the perceptions of the benefits and concerns of shopping on-line. A survey of 224 internet shoppers was conducted and the results indicate that there are only slight differences between the genders regarding on-line shopping behavior and no differences in actual shopping behavior.

  20. 7 CFR 2.88 - Director, Office of Small and Disadvantaged Business Utilization.

    Science.gov (United States)

    2010-01-01

    ... Utilization. 2.88 Section 2.88 Agriculture Office of the Secretary of Agriculture DELEGATIONS OF AUTHORITY BY... Utilization. (a) Delegations. Pursuant to § 2.24 (a)(3), the following delegations of authority are made by... Utilization: (1) The Director, Office of Small and Disadvantaged Business Utilization, under the...

  1. A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

    NARCIS (Netherlands)

    Strange, A.; Capon, F.; Spencer, C.C.; Knight, J.; Weale, M.E.; Allen, M.H.; Barton, A.; Band, G.; Bellenguez, C.; Bergboer, J.G.M.; Blackwell, J.M.; Bramon, E.; Bumpstead, S.J.; Casas, J.P.; Cork, M.J.; Corvin, A.; Deloukas, P.; Dilthey, A.; Duncanson, A.; Edkins, S.; Estivill, X.; Fitzgerald, O.; Freeman, C.; Giardina, E.; Gray, E.; Hofer, A.; Huffmeier, U.; Hunt, S.E.; Irvine, A.D.; Jankowski, J.; Kirby, B.; Langford, C.; Lascorz, J.; Leman, J.; Leslie, S.; Mallbris, L.; Markus, H.S.; Mathew, C.G.; McLean, W.H.I.; McManus, R.; Mossner, R.; Moutsianas, L.; Naluai, A.T.; Nestle, F.O.; Novelli, G.; Onoufriadis, A.; Palmer, C.N.; Perricone, C.; Pirinen, M.; Plomin, R.; Potter, S.C.; Pujol, R.M.; Rautanen, A.; Riveira-Munoz, E.; Ryan, A.W.; Salmhofer, W.; Samuelsson, L.; Sawcer, S.J.; Schalkwijk, J.; Smith, C.H.; Stahle, M.; Su, Z.; Tazi-Ahnini, R.; Traupe, H.; Viswanathan, A.C.; Warren, R.B.; Weger, W.; Wolk, K.; Wood, N.; Worthington, J.; Young, H.S.; Zeeuwen, P.L.J.M.; Hayday, A.; Burden, A.D.; Griffiths, C.E.; Kere, J.; Reis, A.; McVean, G.; Evans, D.M.; Brown, M.A.; Barker, J.N.; Peltonen, L.; Donnelly, P.; Trembath, R.C.

    2010-01-01

    To identify new susceptibility loci for psoriasis, we undertook a genome-wide association study of 594,224 SNPs in 2,622 individuals with psoriasis and 5,667 controls. We identified associations at eight previously unreported genomic loci. Seven loci harbored genes with recognized immune functions (

  2. Dicty_cDB: VFL581 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available tus norvegicus BAC CH230-39O11 (Children's Ho... 42 0.007 2 ( AC103077 ) Rattus n...orvegicus BAC CH230-224J5 (Children's Ho... 42 0.007 2 ( AC117076 ) Dictyostelium discoideum chromosome 2 ma

  3. AcEST: DK953032 [AcEST

    Lifescience Database Archive (English)

    Full Text Available |P09678|SODC_BRAOC Superoxide dismutase [Cu-Zn] OS=Brassica ol... 224 4e-58 sp|O49073|SODC_PAUKA Superoxide dismutase [Cu-Zn] OS=Paul...ownia k... 223 6e-58 sp|Q42612|SODC2_BRAJU Superoxide di

  4. Method of uranium and radium isotopes determination in underground waters by liquid scintillators technique

    International Nuclear Information System (INIS)

    The theoretical bases of the determination of 238U, 234U, 226Ra, 228Ra and 224Ra in underground waters are presented. The extraction of uranium and radium from waters is described. The application of the method in coal mines in Poland is mentioned. 7 refs., 1 fig. (A.S.)

  5. RADIUM IN MARYLAND COASTAL PLAIN GROUND WATER: AN EMERGING ISSUE RESULTING FROM A MULTI-AGENCY STUDY OF CARCINGENS IN WELL WATER

    Science.gov (United States)

    In 1997, radium-226 plus radium-228 concentrations as high as 66 picocuries per liter were detected in domestic well-water samples from the (Cretaceous) Potomac Group and Magothy Formation in Anne Arundel County, Maryland. Furthermore, radium-224 was found to be a major component...

  6. Radium isotopes as a tracer of sediment-water column exchange in the North Sea

    NARCIS (Netherlands)

    Burt, W.J.; Thomas, H.; Pätsch, J.; Omar, A.; Schrum, C.; Daewel, U.; Brenner, H.; de Baar, H.J.W.

    2014-01-01

    Sediment-water column exchange plays an important role in coastal biogeochemistry. We utilize short-lived radium isotopes (224Ra and 223Ra) to understand and quantify the dominant processes governing sediment-water column exchange throughout the North Sea. Our comprehensive survey, conducted in Sept

  7. Students' Motivation and Teachers' Teaching Practices towards the Use of Blogs for Writing of Online Journals

    Science.gov (United States)

    Nair, Shanthi Suraj; Tay, Lee Yong; Koh, Joyce Hwee Ling

    2013-01-01

    This research paper explores students' motivation and teachers' teaching practices towards the writing of compositions in the conventional paper-based (paper and pencil) and the online blogs mode. Six classes of Grade 5 (224 students) and four English teachers in an elementary-level future school in Singapore were involved in this study. A total…

  8. 76 FR 21909 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2011-04-19

    ... addition, Section 454A(e)(1) requires that States create a State Case Registry (SCR) within their statewide... their cases in the SCR. The data being collected for the APD are a combination of narrative, budgets and... 224 Collection of non-IV-D data for SCR: 3,045 412 0.03 37,636.20 Courts States: Transmission to...

  9. 76 FR 62330 - Radio Broadcasting Services; Alamo, GA; Alton, MO; Boscobel, WI; Buffalo, OK; Cove, AR; Clayton...

    Science.gov (United States)

    2011-10-07

    ... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Alamo, GA; Alton, MO; Boscobel, WI; Buffalo, OK; Cove..., under Montana, Channel 254C2. h. Remove Buffalo, under Oklahoma, Channel 224C2; Erick, Channel...

  10. AcEST: DK956766 [AcEST

    Lifescience Database Archive (English)

    Full Text Available 4|BBS4_HUMAN Bardet-Biedl syndrome 4 protein OS=Homo sap... 35 0.32 sp|A7TZE6|SKIT1_MOUSE Selection and upke...SVLGELDKAEEN 343 Y LG KA E+ Sbjct: 212 YLQLGIYQKAFEH 224 >sp|A7TZE6|SKIT1_MOUSE Selection and upkeep of intr

  11. Estradiol, SHBG and leptin interplay with food craving and intake across the menstrual cycle.

    Science.gov (United States)

    Objective: To understand the association between ovarian hormones, non-acute satiety hormones and craving calorie dense foods in the luteal phase. Methods: 17 premenopausal women, mean age 23.2 y, mean BMI 22.4 kg/m2 with regular menstrual cycles were studied during late follicular (FP) and luteal ...

  12. Animal waste and FGD gypsum effects on bermudagrass and soil leachate nutrient contents

    Science.gov (United States)

    In previous experiments on newly relcaimed coal mine soils in northeastern Mississippi, applying poultry litter at 22.4 Mg ha-1 yr-1 enhanced bermudagrass (Cynodon dactylon L.) biomass and selected soil quality parameters. Additionally, co-application of 11.2 Mg ha-1 FGD gypsum and litter reduced so...

  13. 10 CFR Appendix D to Part 835 - Surface Contamination Values

    Science.gov (United States)

    2010-01-01

    ... + Removable) 2,3 U-nat, U-235, U-238, and associated decay products 7 1,000 7 5,000 Transuranics, Ra-226, Ra-228, Th-230, Th-228, Pa-231, Ac-227, I-125, I-129 20 500 Th-nat, Th-232, Sr-90, Ra-223, Ra-224,...

  14. Trainingsdagboeken: theorie en praktijk

    NARCIS (Netherlands)

    Nederhof, E; Volkers, K.; Dekker, W.; Lemmink, K.

    2006-01-01

    Training logs can provide athletes and trainers/coaches with valuable information about the training regime and the athlete's reaction to it. Results from an inventory among 224 Dutch athletes of national (70%) and international (30%) level are presented in combination with findings from scientific

  15. Effectiveness, Teaching, and Assessments: Survey Evidence from Finance Courses

    Science.gov (United States)

    Lai, Ming Ming; Kwan, Jing Hui; Kadir, Hazlina Abdul; Abdullah, Mahdhir; Yap, Voon Choong

    2010-01-01

    The present article examines the effectiveness, teaching, assessment methods, and the importance of finance concepts in three undergraduate finance courses in a private university in Malaysia. Approximately 224 undergraduates (finance majors) were surveyed and demonstrated positive attitudes toward the effectiveness of the finance subjects. The…

  16. Inquiry-Based Learning in Higher Education: Principal Forms, Educational Objectives, and Disciplinary Variations

    Science.gov (United States)

    Aditomo, Anindito; Goodyear, Peter; Bliuc, Ana-Maria; Ellis, Robert A.

    2013-01-01

    Learning through inquiry is a widely advocated pedagogical approach. However, there is currently little systematic knowledge about the practice of inquiry-based learning (IBL) in higher education. This study examined descriptions of learning tasks that were put forward as examples of IBL by 224 university teachers from various disciplines in three…

  17. EST Table: FS752223 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available /09/08 75 %/224 aa FBpp0232921|DvirPros28.1-PA 10/08/28 58 %/205 aa C36B1.4#CE05371#WBGene00003925#locus:pas-4#proteasome A-type subm...it#status:Confirmed#UniProt:Q95005#protein_id:CAB022 69.

  18. Soil Nitrogen Response to Coupling Cover Crops with Manure Injection

    Science.gov (United States)

    Coupling winter small grain cover crops (CC) with manure (M) application may increase retention of manure nitrogen (N) in corn-soybean cropping systems. The objective of this research was to quantify soil N changes after application of liquid swine M (Sus scrofa L.) at target N rates of 112, 224, an...

  19. Enhancing Nutrient Cycling by Coupling Cover Crops with Manure Injection

    Science.gov (United States)

    Coupling winter small grain cover crops (CC) with liquid manure injection may increase manure nutrient capture. The objectives of this research were to quantify manure injection effects using target manure N rates of 112, 224, and 336 kg N ha-1 on CC plant density, fall and spring shoot biomass, N, ...

  20. The Concurrence of Eating Disorders with Histories of Child Abuse among Adolescents.

    Science.gov (United States)

    Hernandez, Jeanne

    1995-01-01

    Examines the relationship between eating disorders and history of physical abuse, incest, and extrafamilial sexual abuse. Results of a survey of adolescents (n=6,224) indicate that eating disorders are correlated with all 3 types of abuse. Presence of an eating disorder also correlates with presence of other addictive behaviors, family history of…

  1. Measurement of nuclides of uranium and thorium series of disequilibrium using γ-spectroscopy

    Institute of Scientific and Technical Information of China (English)

    刘广山; 黄奕普; 李静; 叶林

    2002-01-01

    The decay dynamic equations of two daughters were resolved as initial activities of daughters are not zero, and gave calculation formula of activities for measuring uranium and thorium series of disequilibrium using γ-spectroscopy. 238U, 234Th, 226Ra, 222Rn, 228Ra, 228Th, 224Ra, 212pb, 210pb and 40K in two sediment samples were determined as application.

  2. 77 FR 27253 - Proposed Collection, Laura Bush 21st Century Librarian Grant Program Evaluation

    Science.gov (United States)

    2012-05-09

    ... (FR vol. 76, no. 224, pgs. 72003-72004). No comments were received. Agency: Institute of Museum and... THE ARTS AND THE HUMANITIES Proposed Collection, Laura Bush 21st Century Librarian Grant Program... improvements to the Laura Bush 21st Century Librarian (LB21) Grant Program. The information gathered...

  3. Research in radiobiology. Annual report of work in progress in the internal irradiation program

    International Nuclear Information System (INIS)

    Research progress on studies of the effects of internally deposited radionuclides in dogs, mice, and humans is reported. The studies include toxicity of plutonium 239, radium 226, and radium 224, the kinetics of actinides in beagles, and dosimetry of internal emitters

  4. Influence of pollution of boron chlorinity ratio

    Digital Repository Service at National Institute of Oceanography (India)

    Narvekar, P.V.; Zingde, M.D.

    /CI decreased at locations situated away from the polluting sources. In the histograms showing the frequency distribution of B/CI the range in which most B/CI values prevailed was same as that of unpolluted coastal water (0.224-0.230) whereas, at a location...

  5. Domain Modeling: NP_003411.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_003411.3 chr3 CRYSTAL STRUCTURE OF A DESIGNED ZINC FINGER PROTEIN BOUND TO DNA c1meyf_ chr3/NP_003411.3.../NP_003411.3_holo_219-301.pdb blast 224C,226V,227C,228G,229K,230G,231F,232S,233Q,234S

  6. Domain Modeling: NP_001561.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_001561.3 chr3 Structural Basis for the Interaction of TAK1 Kinase with its Activ...ating Protein TAB1 p2evaa_ chr3/NP_001561.3/NP_001561.3_holo_194-543.pdb psi-blast 216I,217S,218Q,219G,224V,

  7. A Trinomial Analogue of Bailey's Lemma and N=2 Superconformal Invariance

    CERN Document Server

    Andrews, G E

    1997-01-01

    We propose and prove a trinomial version of the celebrated Bailey's lemma. As an application we obtain new fermionic representations for characters of some unitary as well as nonunitary models of N = 2 superconformal field theory (SCFT). We also establish interesting relations between N = 1 and N = 2 models of SCFT with central charges $(3/2) (1 - {2(2-4\

  8. 29 CFR 90.21 - Study.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Study. 90.21 Section 90.21 Labor Office of the Secretary of... Study With Respect to Workers in Industry Which is the Subject of an Investigation for Industry Import Relief § 90.21 Study. (a) Initiation. Upon notification by the Commission, pursuant to section 224 of...

  9. Parturition difficulties in sheep

    NARCIS (Netherlands)

    Grommers, F. J.; Elving, L.; Eldik, P. van

    1985-01-01

    The incidence of difficult parturition was recorded in Texel Sheep lambs (224), Milk Sheep lambs (273) and various crossbreeds (1043) in ten spring lambing seasons. at lambing time the ewes were under 24-hour observation. Difficult parturition is defined as necessity for obstetrical assistance as a

  10. The synthesis of brassinosteroids, a new class of plant hormones

    Science.gov (United States)

    Lakhvich, Fedor A.; Khripach, Vladimir A.; Zhabinskii, Vladimir N.

    1991-06-01

    Data on methods of synthesis of brassinosteroids are correlated. In view of their extremely low reported content in nature, the role of chemical synthesis from other natural steroids as the main source of obtaining these hormones for detailed study and practical use is assessed. The bibliography contains 224 references.

  11. Distribution of Feedback among Teacher and Students in Online Collaborative Learning in Small Groups

    Science.gov (United States)

    Coll, Cesar; Rochera, Maria Jose; de Gispert, Ines; Diaz-Barriga, Frida

    2013-01-01

    This study explores the characteristics and distribution of the feedback provided by the participants (a teacher and her students) in an activity organized inside a collaborative online learning environment. We analyse 853 submissions made by two groups of graduate students and their teacher (N1 = 629 & N2 = 224) involved in the collaborative…

  12. The Relationship between Emotional Intelligence and Problem Solving Skills in Prospective Teachers

    Science.gov (United States)

    Deniz, Sabahattin

    2013-01-01

    This study aims to investigate the relationship between emotional intelligence and problem solving. The sample set of the research was taken from the Faculty of Education of Mugla University by the random sampling method. The participants were 386 students--prospective teachers--(224 females; 182 males) who took part in the study voluntarily.…

  13. AcEST: BP912264 [AcEST

    Lifescience Database Archive (English)

    Full Text Available KGDALLFFSLHPSAVPDESSLHTGCPVIEGEKWSATKWIHVAAFEKPRPKNGACV 224 Query: 195 DEDESCGEWAAYGECQKNPTYMIGTSEQPGY 287 +...HGGCPVIEGEKWSATKWIHV S D G+C Sbjct: 200 AVKPRKGDALLFFNLHPDAIPDPLSLHGGCPVIEGEKWSATKWIHVDSFDRIVTPSGNCT 259 Query: 195 DEDESCG...GDALLFFNLHPDAIPDPLSLHGGCPVIEGEKWSATKWIHVDSFDRIVTPSGNCT 259 Query: 195 DEDESCGEWAAYGECQKNPTYMIGTSEQPGY 287 D ...HGGCPVIEGEKWSATKWIHVDSFDKILKPGGNCT 259 Query: 195 DEDESCGEWAAYGECQKNPTYMIGTSEQPG 284 DE++SC WAA GEC KNP YM+G...GDALLFYSLHPNATPDPLSLHGGCPVIQGEKWSATKWIHVDSFDKTVDTEGNCSD 256 Query: 198 EDESCGEWAAYGECQKNPTYMIGTSEQPGY 287 DE

  14. 76 FR 34541 - Child and Adult Care Food Program Improving Management and Program Integrity

    Science.gov (United States)

    2011-06-13

    ... improve Program management and integrity in the Child and Adult Care Food Program (CACFP), at 67 FR 43447 (June 27, 2002) and at 69 FR 53501 (September 1, 2004). Section 243 of Public Law 106-224, the... rule was issued in proposed form on September 12, 2000 (65 FR 55101). In response to State and...

  15. Invasiveness of Serotypes and Clones of Streptococcus pneumoniae among Children in Finland

    OpenAIRE

    William P Hanage; Kaijalainen, Tarja H.; Ritva K Syrjänen; Auranen, Kari; Leinonen, Maija; Mäkelä, P. Helena; Brian G. Spratt

    2005-01-01

    Streptococcus pneumoniae (the pneumococcus) causes diseases from otitis media to life-threatening invasive infection. The species is extremely antigenically and clonally diverse. We wished to determine odds ratios (ORs) for serotypes and clones of S. pneumoniae that cause invasive disease in Finland. A total of 224 isolates of S. pneumoniae from cases of invasive disease in children

  16. Digital Oblique Aerial Cameras (1): A Survey of Features and Systems

    NARCIS (Netherlands)

    Lemmens, M.J.P.M.

    2014-01-01

    It has become customary for me to provide a survey article on digital aerial cameras in the April issue of GIM International every three years. The previous survey (April 2011; vol. 25:4) addressed small, medium and large-format cameras, while in April 2008 (vol. 22:4) the focus was on sensor archit

  17. 29 CFR 776.23 - Employment in the construction industry.

    Science.gov (United States)

    2010-07-01

    ... Engineering Co., 224 F. (2d) 359 (C.A. 8), certiorari denied 350 U.S. 875; Chambers Construction Co. and L. H... are engaged in work at the site of the construction such as mechanics, laborers, handymen..., but also office, clerical, bookkeeping, auditing, promotional, drafting, engineering, custodial...

  18. Removal of triclocarban and triclosan in a wastewater treatment plant and their accumulations onto the solids

    Science.gov (United States)

    The objective of this study was to investigate the fate of Triclosan (5-chloro-2-[2,4-dichloro-phenoxy]-phenol (TCS) and triclocarban (N-(4-chlorophenyl)-N’-(3,4-dichlorophenyl)urea) (TCC) within a wastewater treatment plant (WWTP). TCS and TCC are bactericidal compounds that have been detected in ...

  19. Fate of triclocarban and triclosan in soils receiving biosolids applications

    Science.gov (United States)

    Triclosan (5-chloro-2-[2,4-dichloro-phenoxy]-phenol (TCS) and triclocarban (N-(4-chlorophenyl)-N’-(3,4-dichlorophenyl)urea) (TCC) are bactericidal compounds that are added to a wide range of household and personal care products such as hand soap, dish washing products, laundry detergents, cleaning w...

  20. Genetic studies of body mass index yield new insights for obesity biology

    NARCIS (Netherlands)

    Locke, Adam E.; Kahali, Bratati; Berndt, Sonja I.; Justice, Anne E.; Pers, Tune H.; Day, Felix R.; Powell, Corey; Vedantam, Sailaja; Buchkovich, Martin L.; Yang, Jian; Croteau-Chonka, Damien C.; Esko, Tonu; Fall, Tove; Ferreira, Teresa; Gustafsson, Stefan; Kutalik, Zoltan; Luan, Jian'an; Maegi, Reedik; Randall, Joshua C.; Winkler, Thomas W.; Wood, Andrew R.; Workalemahu, Tsegaselassie; Faul, Jessica D.; Smith, Jennifer A.; Zhao, Jing Hua; Zhao, Wei; Chen, Jin; Fehrmann, Rudolf; Hedman, Asa K.; Karjalainen, Juha; Schmidt, Ellen M.; Absher, Devin; Amin, Najaf; Anderson, Denise; Beekman, Marian; Bolton, Jennifer L.; Bragg-Gresham, L.; Buyske, Steven; Demirkan, Ayse; Deng, Guohong; Ehret, Georg B.; Feenstra, Bjarke; Feitosa, Mary F.; Fischer, Krista; Goel, Anuj; Gong, Jian; Jackson, Anne U.; Kanoni, Stavroula; Kleber, Marcus E.; Kristiansson, Kati; Lim, Unhee; Lotay, Vaneet; Mangino, Massimo; Leach, Irene Mateo; Medina-Gomez, Carolina; Medland, Sarah E.; Nalls, Michael A.; Palmer, Cameron D.; Pasko, Dorota; Pechlivanis, Sonali; Peters, Marjolein J.; Prokopenko, Inga; Shungin, Dmitry; Stancakova, Alena; Strawbridge, Rona J.; Sung, Yun Ju; Tanaka, Toshiko; Teumer, Alexander; Trompet, Stella; van der Laan, Sander W.; van Setten, Jessica; Van Vliet-Ostaptchouk, Jana V.; Wang, Zhaoming; Yengo, Loic; Zhang, Weihua; Isaacs, Aaron; Albrecht, Eva; Arnlov, Johan; Arscott, Gillian M.; Attwood, Antony P.; Bandinelli, Stefania; Barrett, Amy; Bas, Isabelita N.; Bellis, Claire; Bennett, Amanda J.; Berne, Christian; Blagieva, Roza; Blueher, Matthias; Bohringer, Stefan; Bonnycastle, Lori L.; Boettcher, Yvonne; Boyd, Heather A.; Bruinenberg, Marcel; Caspersen, Ida H.; Chen, Yii-Der Ida; Clarke, Robert; Daw, E. Warwick; de Craen, Anton J. M.; Delgado, Graciela; Dimitriou, Maria; Doney, Alex S. F.; Eklund, Niina; Estrada, Karol; Eury, Elodie; Folkersen, Lasse; Fraser, Ross M.; Garcia, Melissa E.; Geller, Frank; Giedraitis, Vilmantas; Gigante, Bruna; Go, Alan S.; Golay, Alain; Goodall, Alison H.; Gordon, Scott D.; Gorski, Mathias; Grabe, Hans-Joergen; Grallert, Harald; Grammer, Tanja B.; Graessler, Jurgen; Gronberg, Henrik; Groves, Christopher J.; Gusto, Gaeelle; Haessler, Jeffrey; Hall, Per; Haller, Toomas; Hallmans, Goran; Hartman, Catharina A.; Hassinen, Maija; Hayward, Caroline; Heard-Costa, Nancy L.; Helmer, Qinta; Hengstenberg, Christian; Holmen, Oddgeir; Hottenga, Jouke-Jan; James, Alan L.; Jeff, Janina M.; Johansson, Asa; Jolley, Jennifer; Juliusdottir, Thorhildur; Kinnunen, Leena; Koenig, Wolfgang; Koskenvuo, Markku; Kratzer, Wolfgang; Laitinen, Jaana; Lamina, Claudia; Leander, Karin; Lee, Nanette R.; Lichtner, Peter; Lind, Lars; Lindstrom, Jaana; Lo, Ken Sin; Lobbens, Stephane; Lorbeer, Roberto; Lu, Yingchang; Mach, Francois; Magnusson, Patrik K. E.; Mahajan, Anubha; McArdle, Wendy L.; McLachlan, Stela; Menni, Cristina; Merger, Sigrun; Mihailov, Evelin; Milani, Lili; Moayyeri, Alireza; Monda, Keri L.; Morken, Mario A.; Mulas, Antonella; Mueller, Gabriele; Mueller-Nurasyid, Martina; Musk, Arthur W.; Nagaraja, Ramaiah; Noethen, Markus M.; Nolte, Ilja M.; Pilz, Stefan; Rayner, Nigel W.; Renstrom, Frida; Rettig, Rainer; Ried, Janina S.; Ripke, Stephan; Robertson, Neil R.; Rose, Lynda M.; Sanna, Serena; Scharnagl, Hubert; Scholtens, Salome; Schumacher, Fredrick R.; Scott, William R.; Seufferlein, Thomas; Shi, Jianxin; Smith, Albert Vernon; Smolonska, Joanna; Stanton, Alice V.; Steinthorsdottir, Valgerdur; Stirrups, Kathleen; Stringham, Heather M.; Sundstrom, Johan; Swertz, Morris A.; Swift, Amy J.; Syvanen, Ann-Christine; Tan, Sian-Tsung; Tayo, Bamidele O.; Thorand, Barbara; Thorleifsson, Gudmar; Tyrer, Jonathan P.; Uh, Hae-Won; Vandenput, Liesbeth; Verhulst, Frank C.; Vermeulen, Sita H.; Verweij, Niek; Vonk, Judith M.; Waite, Lindsay L.; Warren, Helen R.; Waterworth, Dawn; Weedon, Michael N.; Wilkens, Lynne R.; Willenborg, Christina; Wilsgaard, Tom; Wojczynski, Mary K.; Wong, Andrew; Wrightl, Alan F.; Zhang, Qunyuan; Brennan, Eoin P.; Choi, Murim; Dastani, Zari; Drong, Alexander W.; Eriksson, Per; Franco-Cereceda, Anders; Gadin, Jesper R.; Gharavi, Ali G.; Goddard, Michael E.; Handsaker, Robert E.; Huang, Jinyan; Karpe, Fredrik; Kathiresan, Sekar; Keildson, Sarah; Kiryluk, Krzysztof; Kubo, Michiaki; Lee, Jong-Young; Liang, Liming; Lifton, Richard P.; Ma, Baoshan; McCarroll, Steven A.; McKnight, Amy J.; Min, Josine L.; Moffatt, Miriam F.; Montgomery, Grant W.; Murabito, Joanne M.; Nicholson, George; Nyholt, Dale R.; Okada, Yukinori; Perry, John R. B.; Dorajoo, Rajkumar; Reinmaa, Eva; Salem, Rany M.; Sandholm, Niina; Scott, Robert A.; Stolk, Lisette; Takahashi, Atsushi; Tanaka, Toshihiro; van 't Hooft, Ferdinand M.; Vinkhuyzen, Anna A. E.; Westra, Harm-Jan; Zheng, Wei; Zondervan, Krina T.; Heath, Andrew C.; Arveiler, Dominique; Bakker, Stephan J. L.; Beilby, John; Bergman, Richard N.; Blangero, John; Bovet, Pascal; Campbell, Harry; Caulfield, Mark J.; Cesana, Giancarlo; Chakravarti, Aravinda; Chasman, Daniel I.; Chines, Peter S.; Collins, Francis S.; Crawford, Dana C.; Cupples, L. Adrienne; Cusi, Daniele; Danesh, John; de Faire, Ulf; den Ruijter, Hester M.; Dominiczak, Anna F.; Erbel, Raimund; Erdmann, Jeanette; Eriksson, Johan G.; Farrall, Martin; Felix, Stephan B.; Ferrannini, Ele; Ferrieres, Jean; Ford, Ian; Forouhi, Nita G.; Forrester, Terrence; Franco, Oscar H.; Gansevoort, Ron T.; Gejman, Pablo V.; Gieger, Christian; Gottesman, Omri; Gudnason, Vilmundur; Gyllensten, Ulf; Hall, Alistair S.; Harris, Tamara B.; Hattersley, Andrew T.; Hicks, Andrew A.; Hindorff, Lucia A.; Hingorani, Aroon D.; Hofman, Albert; Homuth, Georg; Hovingh, G. Kees; Humphries, Steve E.; Hunt, Steven C.; Hypponen, Elina; Illig, Thomas; Jacobs, Kevin B.; Jarvelin, Marjo-Riitta; Joeckel, Karl-Heinz; Johansen, Berit; Jousilahti, Pekka; Jukema, J. Wouter; Jula, Antti M.; Kaprio, Jaakko; Kastelein, John J. P.; Keinanen-Kiukaanniemi, Sirkka M.; Kiemeney, Lambertus A.; Knekt, Paul; Kooner, Jaspal S.; Kooperberg, Charles; Kovacs, Peter; Kraja, Aldi T.; Kumari, Meena; Kuusisto, Johanna; Lakka, Timo A.; Langenberg, Claudia; Le Marchand, Laic; Lehtimaki, Terho; Lyssenko, Valeriya; Mannisto, Satu; Marette, Andre; Matise, Tara C.; McKenzie, Colin A.; McKnight, Barbara; Moll, Frans L.; Morris, Andrew D.; Morris, Andrew P.; Murray, Jeffrey C.; Nelis, Mari; Ohlsson, Claes; Oldehinkel, Albertine J.; Ong, Ken K.; Madden, Pamela A. F.; Pasterkamp, Gerard; Peden, John F.; Peters, Annette; Postma, Dirkje S.; Pramstaller, Peter P.; Price, Jackie F.; Qi, Lu; Raitakari, Olli T.; Rankinen, Tuomo; Rao, D. C.; Rice, Treva K.; Ridker, Paul M.; Rioux, John D.; Ritchie, Marylyn D.; Rudan, Igor; Salomaa, Veikko; Samani, Nilesh J.; Saramines, Jouko; Sarzynski, Mark A.; Schunkert, Heribert; Schwarz, Peter E. H.; Sever, Peter; Shuldiner, Alan R.; Sinisalo, Juha; Stolk, Ronald P.; Strauch, Konstantin; Toenjes, Anke; Tregouet, David-Alexandre; Tremblay, Angelo; Tremoli, Elena; Virtamo, Jarmo; Vohl, Marie-Claude; Voelker, Uwe; Waeber, Gerard; Willemsen, Gonneke; Witteman, Jacqueline C.; Zillikens, M. Carola; Adair, Linda S.; Amouyel, Philippe; Asselbergs, Folkert W.; Assimes, Themistocles L.; Bochud, Murielle; Boehm, Bernhard O.; Boerwinkle, Eric; Bornstein, Stefan R.; Bottinger, Erwin P.; Bouchard, Claude; Cauchi, Stephane; Chambers, John C.; Chanock, Stephen J.; Cooper, Richard S.; de Bakker, Paul I. W.; Dedoussis, George; Ferrucci, Luigi; Franks, Paul W.; Froguel, Philippe; Groop, Leif C.; Haiman, Christopher A.; Hamsten, Anders; Hui, Jennie; Hunter, David J.; Hveem, Kristian; Kaplan, Robert C.; Kivimaki, Mika; Kuh, Diana; Laakso, Markku; Liu, Yongmei; Martin, Nicholas G.; Maerz, Winfried; Melbve, Mads; Metspalu, Andres; Moebus, Susanne; Munroe, Patricia B.; Njolstad, Inger; Oostra, Ben A.; Palmer, Colin N. A.; Pedersen, Nancy L.; Perola, Markus; Perusse, Louis; Peters, Ulrike; Power, Chris; Quertermous, Thomas; Rauramaa, Rainer; Rivadeneira, Fernando; Saaristo, Timo E.; Saleheen, Danish; Sattar, Naveed; Schadt, Eric E.; Schlessinger, David; Slagboom, P. Eline; Snieder, Harold; Spector, Tim D.; Thorsteinsdottir, Unnu R.; Stumvoll, Michael; Tuomilehto, Jaakko; Uitterlinden, Andre G.; Uusitupa, Matti; van der Harst, Pim; Walker, Mark; Wallaschofski, Henri; Wareham, Nicholas J.; Watkins, Hugh; Weir, David R.; Wichmann, H-Erich; Wilson, James F.; Zanen, Pieter; Borecki, Ingrid B.; Deloukas, Panos; Fox, Caroline S.; Heid, Iris M.; O'Connell, Jeffrey R.; Strachan, David P.; Stefansson, Kari; van Duijri, Cornelia M.; Abecasis, Goncalo R.; Franke, Lude; Frayling, Timothy M.; McCarthy, Mark I.; Visscher, Peter M.; Scherag, Andre; Willer, Cristen J.; Boehnke, Michael; Mohlke, Karen L.; Lindgren, Cecilia M.; Beckmann, Jacques S.; Barroso, Ines; North, Kari E.; Ingelsson, Erik; Hirschhorn, Joel N.; Loos, Ruth J. F.; Speliotes, Elizabeth K.; Peeters, P; Broekmans, FJM; van Gils, CH; van der Schouw, YT; Fauser, BCJM; Uiterwaal, C.S.P.M.; Bots, Michael L

    2015-01-01

    Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in upto 339,224 individuals