Sample records for acquisition instruments psychopharmacology

  1. Data acquisition instruments: Psychopharmacology

    Energy Technology Data Exchange (ETDEWEB)

    Hartley, D.S. III


    This report contains the results of a Direct Assistance Project performed by Lockheed Martin Energy Systems, Inc., for Dr. K. O. Jobson. The purpose of the project was to perform preliminary analysis of the data acquisition instruments used in the field of psychiatry, with the goal of identifying commonalities of data and strategies for handling and using the data in the most advantageous fashion. Data acquisition instruments from 12 sources were provided by Dr. Jobson. Several commonalities were identified and a potentially useful data strategy is reported here. Analysis of the information collected for utility in performing diagnoses is recommended. In addition, further work is recommended to refine the commonalities into a directly useful computer systems structure.

  2. Pediatric psychopharmacology. (United States)

    Riddle, M A; Kastelic, E A; Frosch, E


    This paper reviews research in pediatric psychopharmacology over the past decade. The authors first discuss social, economic, and other influences on pediatric psychopharmacology research and prescribing patterns including changing models of childhood psychopathology, increased government funding, and changes in industry regulations. Definitions are offered for current research terminology including efficacy, effectiveness, and adverse events. Design trends and new approaches to outcome measurement are also presented. New data from the last 10 years of research is reviewed for each major class of psychotropic agents. Criteria for inclusion in the review are presented and include aspects of study design (placebo-controlled, large sample size), source of funding (government funded vs. industry), and vision (creative applications). Data for short-term efficacy, long-term efficacy, effectiveness, and safety and adverse events are discussed for each class of medication, although for many, there remains little empirical data. Findings for stimulants, selective serotonin reuptake inhibitors, neuroleptics, alpha-adrenergic agonists, mood stabilizers, buproprion, secretin, naltrexone, immune therapies, and natural supplements are all presented. Finally, the authors offer some speculations regarding the future of pediatric psychopharmacology research.

  3. Instrumentation & Data Acquisition System (D AS) Engineer (United States)

    Jackson, Markus Deon


    The primary job of an Instrumentation and Data Acquisition System (DAS) Engineer is to properly measure physical phenomenon of hardware using appropriate instrumentation and DAS equipment designed to record data during a specified test of the hardware. A DAS system includes a CPU or processor, a data storage device such as a hard drive, a data communication bus such as Universal Serial Bus, software to control the DAS system processes like calibrations, recording of data and processing of data. It also includes signal conditioning amplifiers, and certain sensors for specified measurements. My internship responsibilities have included testing and adjusting Pacific Instruments Model 9355 signal conditioning amplifiers, writing and performing checkout procedures, writing and performing calibration procedures while learning the basics of instrumentation.

  4. AHP for the acquisition of biomedical instrumentation. (United States)

    Balestra, Gabriella; Knaflitz, Marco; Massa, Riccardo; Sicuro, Marco


    Health technology management consists of several decision processes including the acquisition of new technology. The purchasing of a new device requires the selection of one among several products taking into account different criteria. When the technology is characterized by large amount of parameters the choice becomes problematical and a support tool is needed. In 2003 Sloane et al. published a study in which they demonstrated the potentialities of the Analytic Hierarchy Process (AHP) to support the selection of a biomedical instrumentation. The work presented here describes the application of AHP to support the quality assessment for the selection of pacemakers and implantable defibrillators and shows that the method is indeed very appropriate for that task.

  5. 76 FR 39234 - Federal Acquisition Regulation; Unique Procurement Instrument Identifier (United States)


    ... Federal Acquisition Regulation; Unique Procurement Instrument Identifier AGENCIES: Department of Defense... Regulation (FAR) to standardize use of unique Procurement Instrument Identifiers (PIID) throughout the..., including the Federal Government, contractors, and the public, to potential duplicate, overlapping, or...

  6. Data acquisition and instrument control system for neutron ...

    Indian Academy of Sciences (India)

    and timer/counter operations. PCL221, a multifunction I/O card, provides 48 programmable I/O lines using two Intel-8255 integrated circuit (IC) chips. Eight lines on each IC constitute a port; hence each IC has three ports (designated as. Figure 1. Schematic block diagram of data acquisition and instrument con- trol system.

  7. Data acquisition and instrument control system for neutron ...

    Indian Academy of Sciences (India)

    A personal computer (PC)-based data acquisition and instrument control system has been developed for neutron spectrometers in Dhruva reactor hall and Guide Tube laboratory. Efforts have been made to make the system versatile so that it can be used for controlling various neutron spectrometers using single end-on ...

  8. Philosophy of clinical psychopharmacology. (United States)

    Aragona, Massimiliano


    The renewal of the philosophical debate in psychiatry is one exciting news of recent years. However, its use in psychopharmacology may be problematic, ranging from self-confinement into the realm of values (which leaves the evidence-based domain unchallenged) to complete rejection of scientific evidence. In this paper philosophy is conceived as a conceptual audit of clinical psychopharmacology. Its function is to criticise the epistemological and methodological problems of current neopositivist, ingenuously realist and evidence-servant psychiatry from within the scientific stance and with the aim of aiding psychopharmacologists in practicing a more self-aware, critical and possibly useful clinical practice. Three examples are discussed to suggest that psychopharmacological practice needs conceptual clarification. At the diagnostic level it is shown that the crisis of the current diagnostic system and the problem of comorbidity strongly influence psychopharmacological results, new conceptualizations more respondent to the psychopharmacological requirements being needed. Heterogeneity of research samples, lack of specificity of psychotropic drugs, difficult generalizability of results, need of a phenomenological study of drug-induced psychopathological changes are discussed herein. At the methodological level the merits and limits of evidence-based practice are considered, arguing that clinicians should know the best available evidence but that guidelines should not be constrictive (due to several methodological biases and rhetorical tricks of which the clinician should be aware, sometimes respondent to extra-scientific, economical requests). At the epistemological level it is shown that the clinical stance is shaped by implicit philosophical beliefs about the mind/body problem (reductionism, dualism, interactionism, pragmatism), and that philosophy can aid physicians to be more aware of their beliefs in order to choose the most useful view and to practice coherently

  9. Psychopharmacology and memory


    Glannon, W


    Psychotropic and other drugs can alter brain mechanisms regulating the formation, storage, and retrieval of different types of memory. These include “off label” uses of existing drugs and new drugs designed specifically to target the neural bases of memory. This paper discusses the use of beta‐adrenergic antagonists to prevent or erase non‐conscious pathological emotional memories in the amygdala. It also discusses the use of novel psychopharmacological agents to enhance long term semantic an...

  10. Data acquisition instrument for EEG based on embedded system (United States)

    Toresano, La Ode Husein Z.; Wijaya, Sastra Kusuma; Prawito, Sudarmaji, Arief; Syakura, Abdan; Badri, Cholid


    An electroencephalogram (EEG) is a device for measuring and recording the electrical activity of brain. The EEG data of signal can be used as a source of analysis for human brain function. The purpose of this study was to design a portable multichannel EEG based on embedded system and ADS1299. The ADS1299 is an analog front-end to be used as an Analog to Digital Converter (ADC) to convert analog signal of electrical activity of brain, a filter of electrical signal to reduce the noise on low-frequency band and a data communication to the microcontroller. The system has been tested to capture brain signal within a range of 1-20 Hz using the NETECH EEG simulator 330. The developed system was relatively high accuracy of more than 82.5%. The EEG Instrument has been successfully implemented to acquire the brain signal activity using a PC (Personal Computer) connection for displaying the recorded data. The final result of data acquisition has been processed using OpenBCI GUI (Graphical User Interface) based through real-time process for 8-channel signal acquisition, brain-mapping and power spectral decomposition signal using the standard FFT (Fast Fourier Transform) algorithm.

  11. Low power data acquisition unit for autonomous geophysical instrumentation (United States)

    Prystai, Andrii


    The development of an autonomous instrumentation for field research is always a challenge which needs knowledge and application of recent advances in technology and components production. Using this information a super-low power, low-cost, stand-alone GPS time synchronized data acquisition unit was created. It comprises an extended utilization of the microcontroller modules and peripherals and special firmware with flexible PLL parameters. The present report is devoted to a discussion of synchronization mode of data sampling in autonomous field instruments with possibility of GPS random breaks. In the result the achieved sampling timing accuracy is better than ± 60 ns without phase jumps and distortion plus fixed shift depending on the sample rate. The main application of the system is for simultaneous measurement of several channels from magnetic and electric sensors in field conditions for magneto-telluric instruments. First utilization of this system was in the new developed versions of LEMI-026 magnetometer and LEMI-423 field station, where it was applied for digitizing of up to 6 analogue channels with 32-bit resolution in the range ± 2.5V, digital filtration (LPF) and maximum sample rate 4kS/s. It is ready for record in 5 minutes after being turned on. Recently, this system was successfully utilized with the drone-portable magnetometers destined for the search of metallic objects, like UXO, in rural areas, research of engineering underground structure and for mapping ore bodies. The successful tests of drone-portable system were made and tests results are also discussed.

  12. Using game format to teach psychopharmacology to medical students. (United States)

    Shiroma, Paulo R; Massa, Alfredo A; Alarcon, Renato D


    Most psychiatric programs provide lectures on basic principles of psychopharmacology. Yet, this traditional approach has been criticized due to excessive information and passive transfer of expert knowledge. An alternative teaching method is the use of "academic games." To investigate medical students' acquisition of knowledge on psychopharmacology, and their perception of a game playing approach compared to traditional lectures. Two senior residents designed, implemented, and executed a randomized pretest-posttest study to teach psychopharmacology, using an academic game and a lecture format, to third-year medical students during a 6-week Psychiatry clerkship. Both didactic interventions were delivered concurrently for five consecutive weeks covering five psychopharmacology modules: antidepressants I (selective serotonin reuptake inhibitors and atypical antidepressants), antidepressants II (monoamine oxidase inhibitors and tricyclic antidepressants), mood stabilizers, antipsychotics, and anti-anxiety agents/sedatives/hypnotics. The game follows similar rules of the famous TV show, "Jeopardy" using a power point grid and a multiple choice question format. Forty-three medical students participated (29 assigned to the game approach, 14 to the traditional lecture approach). None of the demographic variables (age, gender, years after graduation, Graduate Point Averages, and United States Medical Licensing Examination 1) were significantly associated with the pre/posttest score difference between groups. Both groups improved their knowledge on psychotropic drugs [(game group t = 10.86, p game group had a better perception of this educational method as measured by perceived enjoyment, increased knowledge of psychopharmacology, and stimulating interest in the subject compared to those in the lecture group (p academic games can make the learning experience more enjoyable and motivating; however, future studies with higher quality methodology and design are needed to

  13. Trials, tribulations, and pitfalls using commercial instruments for data acquisition

    Energy Technology Data Exchange (ETDEWEB)

    Lee,R.C.; Olsen, R. H.; Unger, K. L.


    Brookhaven National Laboratory's Relativistic Heavy Ion Collider (RHIC) uses many commercially available instruments - for example spectrum analyzers, oscilloscopes, digital volt meters, signal generators - as integral parts of instrumentation and control systems. Typically these systems are remotely controlled. Using commercial instruments has many benefits. Manufactures have the skill, knowledge, and experience to produce high quality products. The price performance ratio is hard to duplicate. There are also disadvantages. Proprietary interfaces, single platform drivers, and reliable operation provide challenges for implementation and unattended operation. Several of the systems used at RHIC will be described. Their issues and solutions will be presented.

  14. Generic Data Acquisition and Instrument control System (GDAIS)


    Haro Negre, Pau


    Premi GMV en l’àmbit de la Tecnologia Espacial al millor Projecte de Fi de Carrera d’Enginyeria de Telecomunicació (curs 2010-2011) English: Remote sensing instrument development usually includes a software interface to control the instrument and acquire data. Although there are a similarities among softwares, it is hardly ever reused, since it is not designed with reusability in mind. The goal of this project is to develop a multi-platform software system to control and acquire data from ...

  15. Concept Acquisition and Confidence Using a Spatial Probability Measure Instrument (United States)

    Moore, David Richard


    Instructional strategies for teaching concepts have long been identified. Less commonly studied is a learner's level of confidence and certitude in their knowledge based upon exposure to these instructional treatments. This experimental research study used an instrument referred to as the Spatial Probability Measure (SPM) to solicit levels of…

  16. Autonomous site selection and instrument positioning for sample acquisition (United States)

    Shaw, A.; Barnes, D.; Pugh, S.

    The European Space Agency Aurora Exploration Program aims to establish a European long-term programme for the exploration of Space, culminating in a human mission to space in the 2030 timeframe. Two flagship missions, namely Mars Sample Return and ExoMars, have been proposed as recognised steps along the way. The Exomars Rover is the first of these flagship missions and includes a rover carrying the Pasteur Payload, a mobile exobiology instrumentation package, and the Beagle 2 arm. The primary objective is the search for evidence of past or present life on mars, but the payload will also study the evolution of the planet and the atmosphere, look for evidence of seismological activity and survey the environment in preparation for future missions. The operation of rovers in unknown environments is complicated, and requires large resources not only on the planet but also in ground based operations. Currently, this can be very labour intensive, and costly, if large teams of scientists and engineers are required to assess mission progress, plan mission scenarios, and construct a sequence of events or goals for uplink. Furthermore, the constraints in communication imposed by the time delay involved over such large distances, and line-of-sight required, make autonomy paramount to mission success, affording the ability to operate in the event of communications outages and be opportunistic with respect to scientific discovery. As part of this drive to reduce mission costs and increase autonomy the Space Robotics group at the University of Wales, Aberystwyth is researching methods of autonomous site selection and instrument positioning, directly applicable to the ExoMars mission. The site selection technique used builds on the geometric reasoning algorithms used previously for localisation and navigation [Shaw 03]. It is proposed that a digital elevation model (DEM) of the local surface, generated during traverse and without interaction from ground based operators, can be

  17. Control and acquisition system of a space instrument for cosmic ray measurement (United States)

    Prieto, M.; Martín, C.; Quesada, M.; Meziat, D.; Medina, J.; Sánchez, S.; Rodríguez-Frías, M. D.


    The PESCA Instrument Control and Acquisition System (PICAS) design, building and tests are presented. The purpose of the PESCA instrument is the study of the Solar Energetic Particles and the Anomalous Cosmic Rays. It is, therefore, a satellite on-board instrument. The PICAS is basically a computer, composed of a microprocessor with a memory block and a set of interfaces for the communication with the rest of the instrument and the satellite. The PICAS manages all the comunication processes with the satellite, that comprises the order reception from the ground station, and the telemetry sending, that includes scientific data and housekeeping data. By means of telecommands, the PICAS is completely controllable from the ground. The PICAS is also a reliable data acquisition system that guarantees the correct reception of the Cosmic Rays data collected in the ground.

  18. Rapid Learning of an Abstract Language-Specific Category: Polish Children's Acquisition of the Instrumental Construction (United States)

    Dabrowska, Ewa; Tomasello, Michael


    Rapid acquisition of linguistic categories or constructions is sometimes regarded as evidence of innate knowledge. In this paper, we examine Polish children's early understanding of an idiosyncratic, language-specific construction involving the instrumental case--which could not be due to innate knowledge. Thirty Polish-speaking children aged 2; 6…

  19. An Inexpensive, Open-Source USB Arduino Data Acquisition Device for Chemical Instrumentation. (United States)

    Grinias, James P; Whitfield, Jason T; Guetschow, Erik D; Kennedy, Robert T


    Many research and teaching labs rely on USB data acquisition devices to collect voltage signals from instrumentation. However, these devices can be cost-prohibitive (especially when large numbers are needed for teaching labs) and require software to be developed for operation. In this article, we describe the development and use of an open-source USB data acquisition device (with 16-bit acquisition resolution) built using simple electronic components and an Arduino Uno that costs under $50. Additionally, open-source software written in Python is included so that data can be acquired using nearly any PC or Mac computer with a simple USB connection. Use of the device was demonstrated for a sophomore-level analytical experiment using GC and a CE-UV separation on an instrument used for research purposes.

  20. Design details of Intelligent Instruments for PLC-free Cryogenic measurements, control and data acquisition (United States)

    Antony, Joby; Mathuria, D. S.; Chaudhary, Anup; Datta, T. S.; Maity, T.


    Cryogenic network for linear accelerator operations demand a large number of Cryogenic sensors, associated instruments and other control-instrumentation to measure, monitor and control different cryogenic parameters remotely. Here we describe an alternate approach of six types of newly designed integrated intelligent cryogenic instruments called device-servers which has the complete circuitry for various sensor-front-end analog instrumentation and the common digital back-end http-server built together, to make crateless PLC-free model of controls and data acquisition. These identified instruments each sensor-specific viz. LHe server, LN2 Server, Control output server, Pressure server, Vacuum server and Temperature server are completely deployed over LAN for the cryogenic operations of IUAC linac (Inter University Accelerator Centre linear Accelerator), New Delhi. This indigenous design gives certain salient features like global connectivity, low cost due to crateless model, easy signal processing due to integrated design, less cabling and device-interconnectivity etc.

  1. Cultural and Ethnic Issues in Psychopharmacology

    National Research Council Canada - National Science Library

    Keh-Ming Lin


    Since the inception of the modern era of psychopharmacology, psychotropics have been the mainstay of the care of psychiatric patients all over the world, irrespective of their cultural and ethnic backgrounds...

  2. LabVIEW: a software system for data acquisition, data analysis, and instrument control. (United States)

    Kalkman, C J


    Computer-based data acquisition systems play an important role in clinical monitoring and in the development of new monitoring tools. LabVIEW (National Instruments, Austin, TX) is a data acquisition and programming environment that allows flexible acquisition and processing of analog and digital data. The main feature that distinguishes LabVIEW from other data acquisition programs is its highly modular graphical programming language, "G," and a large library of mathematical and statistical functions. The advantage of graphical programming is that the code is flexible, reusable, and self-documenting. Subroutines can be saved in a library and reused without modification in other programs. This dramatically reduces development time and enables researchers to develop or modify their own programs. LabVIEW uses a large amount of processing power and computer memory, thus requiring a powerful computer. A large-screen monitor is desirable when developing larger applications. LabVIEW is excellently suited for testing new monitoring paradigms, analysis algorithms, or user interfaces. The typical LabVIEW user is the researcher who wants to develop a new monitoring technique, a set of new (derived) variables by integrating signals from several existing patient monitors, closed-loop control of a physiological variable, or a physiological simulator.

  3. Instrumentation and data acquisition for full-scale aircraft crash testing (United States)

    Jones, Lisa E.; Fasanella, Edwin L.


    The Landing and Impact Dynamics Branch of the NASA Langley Research Center has been conducting full-scale aircraft crash tests since the 1970s. Using a pendulum method, aircraft are suspended by cables from a 240-ft high gantry and swung into the impact surface at various attitudes and velocities. Instrumentation for these tests include on-board high-speed cameras, strain gages, load cells, displacement transducers, and accelerometers. Transducers in the aircraft are hard-wired through a long umbilical cable to the data acquisition room. Up to 96 channels of data can be collected at a typical rate of 4000 samples per second. Data acquisition using an FM multiplexed analog system and a high-speed personal computer based digital system is described.

  4. Psychopharmacologic treatment of borderline personality disorder (United States)

    Ripoll, Luis H.


    The best available evidence for psychopharmacologic treatment of borderline personality disorder (BPD) is outlined here. BPD is defined by disturbances in identity and interpersonal functioning, and patients report potential medication treatment targets such as impulsivity, aggression, transient psychotic and dissociative symptoms, and refractory affective instability Few randomized controlled trials of psychopharmacological treatments for BPD have been published recently, although multiple reviews have converged on the effectiveness of specific anticonvulsants, atypical antipsychotic agents, and omega-3 fatty acid supplementation. Stronger evidence exists for medication providing significant improvements in impulsive aggression than in affective or other interpersonal symptoms. Future research strategies will focus on the potential role of neuropeptide agents and medications with greater specificity for 2A serotonin receptors, as well as optimizing concomitant implementation of evidence-based psychotherapy and psychopharmacology, in order to improve BPD patients' overall functioning. PMID:24174895

  5. The psychopharmacological management of eating disorders in ...

    African Journals Online (AJOL)

    In this review we synthesised current literature on the psychopharmacological management of eating disorders (EDs) in children and adolescents (C&As). We focus specifically on anorexia nervosa (AN), bulimia nervosa (BN) and binge eating disorder (BED). The treatment of EDs is determined by physical and ...

  6. Data acquisition and control using National Instruments' LabVIEW'' software

    Energy Technology Data Exchange (ETDEWEB)

    Kirkman, I.W.; Buksh, P.A. (SERC Daresbury Laboratory, Warrington, Cheshire WA4 4AD (United Kingdom))


    Using conventional programming techniques for the production of data acquisition and control software can be a time-consuming procedure, and the code subsequently produced can often be inflexible and rather difficult to modify in the light of changing experimental requirements. A new generation of commercial software products have recently appeared which it is claimed can significantly reduce development times and give rise to more flexible code and improved user interfaces. An example of such a product is National Instruments' LabVIEW,'' which presents a novel graphical approach based on Apple Macintosh computer platforms. Extensive use of LabVIEW has been made by the Soft X-ray Group at Daresbury Laboratory over the past two years, and its performance is reported on here. Several examples of experimental arrangements for which it has been used are described, and an evaluation of the product is made.

  7. Development of high-availability ATCA/PCIe data acquisition instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Correia, Miguel; Sousa, Jorge; Batista, Antonio J.N.; Combo, Alvaro; Santos, Bruno; Rodrigues, Antonio P.; Carvalho, Paulo F.; Goncalves, Bruno [Instituto de Plasmas e Fusao Nuclear, Instituto Superior Tecnico, Universidade de Lisboa, 1049- 001 Lisboa (Portugal); Correia, Carlos M.B.A. [Centro de Instrumentacao, Dept. de Fisica, Universidade de Coimbra, 3004-516 Coimbra (Portugal)


    Latest Fusion energy experiments envision a quasi-continuous operation regime. In consequence, the largest experimental devices, currently in development, specify high-availability (HA) requirements for the whole plant infrastructure. HA features enable the whole facility to perform seamlessly in the case of failure of any of its components, coping with the increasing duration of plasma discharges (steady-state) and assuring safety of equipment, people, environment and investment. IPFN developed a control and data acquisition system, aiming for fast control of advanced Fusion devices, which is thus required to provide such HA features. The system is based on in-house developed Advanced Telecommunication Computing Architecture (ATCA) instrumentation modules - IO blades and data switch blades, establishing a PCIe network on the ATCA shelf's back-plane. The data switch communicates to an external host computer through a PCIe data network. At the hardware management level, the system architecture takes advantage of ATCA native redundancy and hot swap specifications to implement fail-over substitution of IO or data switch blades. A redundant host scheme is also supported by the ATCA/PCIe platform. At the software level, PCIe provides implementation of hot plug services, which translate the hardware changes to the corresponding software/operating system devices. The paper presents how the ATCA and PCIe based system can be setup to perform with the desired degree of HA, thus being suitable for advanced Fusion control and data acquisition systems. (authors)

  8. A LabVIEW-based data acquisition system for the UTEP/Orsay Instrumented Collimator

    Energy Technology Data Exchange (ETDEWEB)

    Puga, A.; Cole, P.L. [UTEP, El Paso TX (United States)


    Full text: We have successfully employed an instrumented collimator of aperture 2 mm for the g8a run (summer, 2001) in Hall B of Jefferson Lab, which was designed and tested by UTEP and engineered and built by the Institut de Physique Nucl ire in Orsay, France. The instrumentation of the collimator consists of four radially mounted scintillator + light guide + PMT elements possessing a left-right, up-down symmetry, which afforded the beam of photons to be precisely aligned to the central axis of the collimator. The collimator was sensitive to rather modest beam motion of the order of a few tens of microns. We made use of the physical fact that the emission angle of the coherent Bremsstrahlung photon component is correlated with its energy for enhancing the degree of polarization of the photon beam. We can extract the spectral peak by tightly collimating the beam and thereby reduce the incoherent background, which further serves to increase the degree of polarization. The maximum polar angle is limited by the opening angle of the collimator, which gives the lower limit for the coherent Bremsstrahlung photon energy. To achieve polarizations exceeding 75%, we must collimate the beam to better than one half of a characteristic angle. This means for a collimator-goniometer distance of 22 m, the aperture of the collimator should be {approx} 2 mm for an incident electron energy of E{sub o} 5.7 GeV. We will report primarily on the bench top data acquisition system (DAQ), which interfaced LabVIEW through a SCSI connection to the VME back plane to readout CAEN QDC{sub s}. We employed this DAQ to test and calibrate the instrumented collimator. Our efforts were quite successful in that the device functioned beyond design specifications within one hour after the photon beam was directed onto the bore hole of the collimator. (Author)

  9. Statistical methodologies in psychopharmacology: a review. (United States)

    Nieminen, Pentti; Miettunen, Jouko; Koponen, Hannu; Isohanni, Matti


    There has been a greatly increased interest in statistical methods in the psychiatric research and its applications over the past few decades, in parallel with advances in computers and statistical software. This review aims to describe the main topics related to statistical methods in psychopharmacology, namely nature of statistics in medicine, problems in data analysis, statistical modelling, developments in statistical technology, statistical reporting and meta-analysis. Copyright (c) 2006 John Wiley & Sons, Ltd.

  10. Monitoring of HTS compound library quality via a high-resolution image acquisition and processing instrument. (United States)

    Baillargeon, Pierre; Scampavia, Louis; Einsteder, Ross; Hodder, Peter


    This report presents the high-resolution image acquisition and processing instrument for compound management applications (HIAPI-CM). The HIAPI-CM combines imaging spectroscopy and machine-vision analysis to perform rapid assessment of high-throughput screening (HTS) compound library quality. It has been customized to detect and classify typical artifacts found in HTS compound library microtiter plates (MTPs). These artifacts include (1) insufficient volume of liquid compound sample, (2) compound precipitation, and (3) colored compounds that interfere with HTS assay detection format readout. The HIAPI-CM is also configured to automatically query and compare its analysis results to data stored in a LIMS or corporate database, aiding in the detection of compound registration errors. To demonstrate its capabilities, several compound plates (n=5760 wells total) containing different artifacts were measured via automated HIAPI-CM analysis, and results compared with those obtained by manual (visual) inspection. In all cases, the instrument demonstrated high fidelity (99.8% empty wells; 100.1% filled wells; 94.4% for partially filled wells; 94.0% for wells containing colored compounds), and in the case of precipitate detection, the HIAPI-CM results significantly exceeded the fidelity of visual observations (220.0%). As described, the HIAPI-CM allows for noninvasive, nondestructive MTP assessment with a diagnostic throughput of about 1min per plate, reducing analytical expenses and improving the quality and stewardship of HTS compound libraries. Copyright © 2011 Society for Laboratory Automation and Screening. Published by Elsevier Inc. All rights reserved.

  11. Treatment of Bulimia Nervosa: Psychological and Psychopharmacologic Considerations. (United States)

    Phillips, Elaine L.; Greydanus, Donald E.; Pratt, Helen D.; Patel, Dilip R.


    Reviews the current literature on psychological and psychopharmacologic treatments for bulimia nervosa in the adolescent population. Describes the two most researched psychological treatments--cognitive behavior therapy and interpersonal therapy--in terms of treatment protocols and outcome research. Reviews psychopharmacologic treatment, including…

  12. Psychopharmacology of the hallucinogenic sage Salvia divinorum. (United States)

    Prisinzano, Thomas E


    At present, the Mexican mint Salvia divinorum is an unregulated hallucinogen. This has resulted in various on-line botanical companies advertising and selling S. divinorum as a legal alternative to other regulated plant hallucinogens. It is predictable that its misuse will increase rapidly. The active ingredient in S. divinorum is the neoclerodane diterpene, salvinorin A (1a), which has been shown to be a kappa agonist both in vitro and in vivo. This review will cover the current state of research into the psychopharmacology of S. divinorum.

  13. Precision medicine for psychopharmacology: a general introduction. (United States)

    Shin, Cheolmin; Han, Changsu; Pae, Chi-Un; Patkar, Ashwin A


    Precision medicine is an emerging medical model that can provide accurate diagnoses and tailored therapeutic strategies for patients based on data pertaining to genes, microbiomes, environment, family history and lifestyle. Here, we provide basic information about precision medicine and newly introduced concepts, such as the precision medicine ecosystem and big data processing, and omics technologies including pharmacogenomics, pharamacometabolomics, pharmacoproteomics, pharmacoepigenomics, connectomics and exposomics. The authors review the current state of omics in psychiatry and the future direction of psychopharmacology as it moves towards precision medicine. Expert commentary: Advances in precision medicine have been facilitated by achievements in multiple fields, including large-scale biological databases, powerful methods for characterizing patients (such as genomics, proteomics, metabolomics, diverse cellular assays, and even social networks and mobile health technologies), and computer-based tools for analyzing large amounts of data.

  14. Psychopharmacology of the endocannabinoids: far beyond anandamide. (United States)

    Pamplona, F A; Takahashi, R N


    The study of endocannabinoid pharmacology has proceeded from the discovery of Δ9-tetrahydrocannabinol, the main psychoactive compound in Cannabis sativa, to the identification of an endogenous endocannabinoid system that is essential for physiological modulation of neuronal functions. We have not yet achieved a complete understanding of the various roles of the endocannabinoids, but this is one of the fastest-growing fields in psychopharmacology. This review starts with a brief historical description of the discovery of the endocannabinoids and then focuses on recent pharmacological advances and recently discovered endocannabinoid mechanisms of action (e.g. functional selectivity, allosterism, and receptor trafficking). Finally, we will discuss the contention that the existence of evidence-based therapeutic applications for cannabinoids and the wide range of physiological functions affected by endocannabinoids suggests that the careful study of the endocannabinoid system may lead to the development of novel therapeutic drugs with higher societal acceptability and lower side effects profiles.

  15. Design of bridge crane girder strain acquisition system based on virtual instrument

    Directory of Open Access Journals (Sweden)

    Wenxue LIU

    Full Text Available Girder is an important part of the bridge crane, which is also the main force element. In order to prevent accidents, it is necessary to collect the bridge crane girder stress data to analyse the fatigue life. This paper constructs a bridge crane girder strain acquisition system. The hardware system consists of sensors, connectors, data acquisition cards, wireless data transmission groups, POE power and host computer. The software system consists of NI MAX to interface with the computer's NI hardware and software resources,and LabVIEW programming to display and storage the girder strain data. Through this system, positions and working days strain data acquisition for the 50/10 t bridge crane girder gets the key positions strain data. The results show that the girder strain data acquisition system runs stably, channel signals of acquisition task transmit accurately, and the terminal data stores competely, meeting the detection requirements, which provides an important data support for the subsequent fatigue analysis and accurate remaining service life prediction of the crane girder.

  16. Data Acquisition Programming (LabVIEW): An Aid to Teaching Instrumental Analytical Chemistry. (United States)

    Gostowski, Rudy

    A course was developed at Austin Peay State University (Tennessee) which offered an opportunity for hands-on experience with the essential components of modern analytical instruments. The course aimed to provide college students with the skills necessary to construct a simple model instrument, including the design and fabrication of electronic…

  17. Acquisition of Raman spectra of amino acids using portable instruments: Outdoor measurements and comparison (United States)

    Culka, A.; Jehlička, J.; Edwards, H. G. M.


    Raman spectra of 13 amino acids: L-alanine, β-alanine, L-asparagine, L-aspartic acid, L-glutamic acid, L-glutamine, glycine, L-methionine, L-proline, L-serine, L-threonine, L-tryptophan and L-tyrosine were acquired outdoors using two portable Raman instruments from the Ahura and Delta Nu manufacturers, both with 785 nm laser excitation. Both instruments provide quality Raman spectra with nevertheless a variable dependence upon the prevailing experimental conditions. The data acquired in these experiments will inform the selection of suitable Raman spectrometers for the in-field detection of biomolecules of relevance to the search for life signatures spectroscopically in terrestrial extreme environments and in extraterrestrial exploration, especially of planetary surfaces and subsurfaces using robotic instrumentation.

  18. Acquisition of a High Performance Computing Instrument for Big Data Research and Education (United States)


    for big data research and education at North Carolina Agricultural and Technical State University (NCA&T). This instrument will promote innovation and...translational big data research at NCA&T. It will make NCA&T (a land grant HBCU) a strong player in big data research and education. The research...Science, Computer Systems Technology, and Electrical and Computer Engineering at 1. REPORT DATE (DD-MM-YYYY) 4. TITLE AND SUBTITLE 13. SUPPLEMENTARY

  19. Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Decreton, M


    SCK-CEN's research and development programme on instrumentation involves the assessment and the development of sensitive measurement systems used within a radiation environment. Particular emphasis is on the assessment of optical fibre components and their adaptability to radiation environments. The evaluation of ageing processes of instrumentation in fission plants, the development of specific data evaluation strategies to compensate for ageing induced degradation of sensors and cable performance form part of these activities. In 2000, particular emphasis was on in-core reactor instrumentation applied to fusion, accelerator driven and water-cooled fission reactors. This involved the development of high performance instrumentation for irradiation experiments in the BR2 reactor in support of new instrumentation needs for MYRRHA, and for diagnostic systems for the ITER reactor.

  20. Resource Prospector Instrumentation for Lunar Volatiles Prospecting, Sample Acquisition and Processing (United States)

    Captain, J.; Elphic, R.; Colaprete, A.; Zacny, Kris; Paz, A.


    Data gathered from lunar missions within the last two decades have significantly enhanced our understanding of the volatile resources available on the lunar surface, specifically focusing on the polar regions. Several orbiting missions such as Clementine and Lunar Prospector have suggested the presence of volatile ices and enhanced hydrogen concentrations in the permanently shadowed regions of the moon. The Lunar Crater Observation and Sensing Satellite (LCROSS) mission was the first to provide direct measurement of water ice in a permanently shadowed region. These missions with other orbiting assets have laid the groundwork for the next step in the exploration of the lunar surface; providing ground truth data of the volatiles by mapping the distribution and processing lunar regolith for resource extraction. This next step is the robotic mission Resource Prospector (RP). Resource Prospector is a lunar mission to investigate 'strategic knowledge gaps' (SKGs) for in-situ resource utilization (ISRU). The mission is proposed to land in the lunar south pole near a permanently shadowed crater. The landing site will be determined by the science team with input from broader international community as being near traversable landscape that has a high potential of containing elevated concentrations of volatiles such as water while maximizing mission duration. A rover will host the Regolith & Environment Science and Oxygen & Lunar Volatile Extraction (RESOLVE) payload for resource mapping and processing. The science instruments on the payload include a 1-meter drill, neutron spectrometer, a near infrared spectrometer, an operations camera, and a reactor with a gas chromatograph-mass spectrometer for volatile analysis. After the RP lander safely delivers the rover to the lunar surface, the science team will guide the rover team on the first traverse plan. The neutron spectrometer (NS) and near infrared (NIR) spectrometer instruments will be used as prospecting tools to guide

  1. An evaluation of strain and temperature instrumentation technology used for SRM nozzle static test data acquisition (United States)

    Lanius, S. J.; Brasfield, R. G.


    A program to investigate the status of strain gauge, thermocouple, and attachment technology as used in solid rocket motor static tests is being conducted. The objective for the first part of this program is to critically evaluate strain and temperature measuring instruments for material, configuration, and application deficiencies. Results of the component and application analysis and recommendations for the development of alternatives are presented. The analysis includes evaluation of strain and temperature transducers, lead wires, attachment and signal conditioning/data reduction technologies and procedures.

  2. Real world instrumentation with Python automated data acquisition and control systems

    CERN Document Server

    Hughes, John


    Learn how to develop your own applications to monitor or control instrumentation hardware. Whether you need to acquire data from a device or automate its functions, this practical book shows you how to use Python's rapid development capabilities to build interfaces that include everything from software to wiring. You get step-by-step instructions, clear examples, and hands-on tips for interfacing a PC to a variety of devices. Use the book's hardware survey to identify the interface type for your particular device, and then follow detailed examples to develop an interface with Python and C. O

  3. The ethics of psychopharmacological research in legal minors

    Directory of Open Access Journals (Sweden)

    Koelch Michael


    Full Text Available Abstract Research in psychopharmacology for children and adolescents is fraught with ethical problems and tensions. This has practical consequences as it leads to a paucity of the research that is essential to support the treatment of this vulnerable group. In this article, we will discuss some of the ethical issues which are relevant to such research, and explore their implications for both research and standard care. We suggest that finding a way forward requires a willingness to acknowledge and discuss the inherent conflicts between the ethical principles involved. Furthermore, in order to facilitate more, ethically sound psychopharmacology research in children and adolescents, we suggest more ethical analysis, empirical ethics research and ethics input built into psychopharmacological research design.

  4. Instrumentation and control systems for monitoring and data acquisition for thermal recovery process

    Energy Technology Data Exchange (ETDEWEB)

    Aparicio, J.; Hernandez, E.; Perozo, H. [PDVSA Intevep, S.A. (Venezuela)


    Thermal recovery methods are often applied to enhance oil recovery in heavy oil reservoirs, one of its challenges is to control the displacement of the thermal front. Methods are thus implemented to obtain data on the temperatures in the wells at any given time and to monitor other variables so that the behaviour of the thermal front can be predicted. The aim of this paper is to present a new control and instrumentation scheme to measure all of the variables. A software was created using Labview a graphs-based programming language software and PostgreSQL, a database management system. Using this software, sensors can be added or removed at any time; trends can be immediately visualized; and quality of the information is ensured since there is no human intervention in the data collection or processing. This paper presented a software which improves monitoring of all of the variables affecting the behaviour of the thermal front.

  5. Obstruction of valid race/ethnicity data acquisition by current data collection instruments. (United States)

    Dakis, P; Rubin, L


    Methods of collecting race/ethnicity data affect the validity of conclusions based on them as do other factors such as lack of consensus and inadequate definitions for terminology; and misclassification or miscounting of patients. Current data collection instruments do not identify mixed heritage. We propose improving data measurement and collection by including a quantified multiracial/multiethnic heritage category for persons of mixed heritage; a don't know category; and a refuse to reveal category. The resulting problems affect all uses of racial and ethnic data, including health care provision, research, and health planning. More precise race/ethnicity categories should be encouraged by such means as a 16-category checklist (with instructions to check all which apply) currently in development. The Methods section of all clinical, epidemiologic, and pharmacologic reports should include descriptions of racial measurement and reasons for including or excluding clearly defined populations.

  6. Conventional research house planning, acquisition, instrumentation, and characterization tests. Topical report, December 1983-August 1986

    Energy Technology Data Exchange (ETDEWEB)

    Zawacki, T.S.; Foote, D.F.; Ketels, P.A.; Banasiuk, H.; Elkins, R.H.


    A 30-year-old, one-story, detached, single-family dwelling, with full basement, three bedrooms, and a floor area of 1150 square feet, was acquired, instrumented, and was characterized during the 1985-86 heating season. This conventional research house is located in Chicago, Illinois, and was selected because it is typical of a very large segment of existing houses in the East-North-Central region of the U.S. For the heating-characterization test, the house was equipped with a natural-gas-fired, central forced-air, power-vented, heat-pipe furnace and a storage water heater; a powered humidifier; electronic air cleaner; and a central electric air conditioner. The results of these tests will serve as the baseline for testing zoned warm-air furnaces, desiccant cooling, gas-fired heat pumps, and other advanced gas appliances.

  7. Instruments

    Energy Technology Data Exchange (ETDEWEB)

    Buehrer, W. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)


    The present paper mediates a basic knowledge of the most commonly used experimental techniques. We discuss the principles and concepts necessary to understand what one is doing if one performs an experiment on a certain instrument. (author) 29 figs., 1 tab., refs.

  8. Psychopharmacological properties of the saponin fraction of Ficus ...

    African Journals Online (AJOL)

    The psychopharmacological effects of a saponin-rich fraction (SFG) obtained from crude methanolic extract of Ficus platyphylla stem bark were studied on spontaneous motor activity (SMA), pentobarbitalinduced sleep, motor coordination, amphetamine-induced hyperactivity and stereotyped behaviour, catalepsy, forced ...

  9. Unmet needs in paediatric psychopharmacology : Present scenario and future perspectives

    NARCIS (Netherlands)

    Persico, Antonio M.; Arango, Celso; Buitelaar, Jan K.; Correll, Christoph U.; Glennon, Jeffrey C.; Hoekstra, Pieter J.; Moreno, Carmen; Vitiello, Benedetto; Vorstman, Jacob|info:eu-repo/dai/nl/304817023; Zuddas, Alessandro


    Paediatric psychopharmacology holds great promise in two equally important areas of enormous biomedical and social impact, namely the treatment of behavioural abnormalities in children and adolescents, and the prevention of psychiatric disorders with adolescent- or adult-onset. Yet, in striking

  10. Acquisition and performance of goal-directed instrumental actions depends on ERK signaling in distinct regions of dorsal striatum in rats (United States)

    Shiflett, Michael W.; Brown, Robert A.; Balleine, Bernard W.


    The performance of goal-directed actions relies on an animal’s prior knowledge of the outcomes or consequences that result from its actions. Additionally, a sensorimotor learning process linking environmental stimuli with actions influences instrumental performance by selecting actions for further evaluation. These distinct decision-making processes in rodents depend on separate sub-regions of the dorsal striatum. Whereas the posterior dorsomedial striatum (pDMS) is required for the encoding of actions with their outcomes or consequences, the dorsolateral striatum (DLS) mediates action-selection based on sensorimotor learning. However, the molecular mechanisms within these brain regions that support learning and performance of goal-directed behavior are not known. Here we show that activation of extracellular signal-regulated kinase (ERK) in the dorsal striatum has a critical role in learning and performance of instrumental goal-directed behavior in rodents. We observed an increase in p42 ERK (ERK2) activation in both the pDMS and DLS during both the acquisition and performance of recently acquired instrumental goal-directed actions. Furthermore, disruption of ERK activation in the pDMS prevented both the acquisition of action-outcome associations, as well as the performance of goal-directed actions guided by previously acquired associations, whereas disruption of ERK activation in the DLS disrupted instrumental performance while leaving instrumental action-outcome learning intact. These results provide evidence of a critical, region-specific role for ERK signaling in the dorsal striatum during the acquisition of instrumental learning and suggest that processes sensitive to ERK signaling within these striatal subregions interact to control instrumental performance after initial acquisition. PMID:20181592

  11. PET application in psychiatry and psychopharmacology

    Energy Technology Data Exchange (ETDEWEB)

    Suhara, Tetsuya [National Inst. of Radiological Sciences, Chiba (Japan)


    In the last few decades diagnostic and research tools in the medical field have made great advances, yet psychiatry has lacked sufficiently sensitive tools to measure the aberration of brain functions. Recently however, the development of Positron emission tomography (PET) techniques has made it possible to measure changes in neurochemical components in mental disorders and the effect of psychoactive drugs in living human brain. Most of the advancement in the psychiatric field has came from the development psychoactive drugs. Brain research involving identification of neurotransmission is largely based on compounds developed in psychopharmacology. Some of these compounds have been radiolabelled and used as radioligands for quantitative examination of neuroreceptors and other aspects of neurotransmission. Using PET, radioligand binding can now be examined in the human brain in vivo. PET techniques also allow examination of an unlabelled drug by examination of its interaction with a radioligand. So one potential of PET in psychiatry is to investigate the mechanism of psychoactive drugs. Antidepressants modulate serotonin transmission by inhibiting serotonin reuptake from the synaptic cleft. High affinity [{sup 3}H]imipramine binding sites in mammalian brain have been labelled to investigate serotonin transporters in living human brain by PET. Cyanoimipramine which is described as a potent serotonin reuptake inhibitor, was labelled with {sup 11}C. In a PET experiment with 6 healthy human subjects, a high accumulation of [{sup 11}C]cyanoimipramine was found in the thalamus and striatum and lowest accumulation was observed in the cerebellum, a region relatively void of serotonin transporters. The thalamus to cerebellum ratio was about 2 at 90 min after the injection of the tracer. Recently, [{sup 11}C]McN5652-X has been introduced as a better tracer for serotonin transporter imaging. Employing [{sup 11}C]McN5652-X in a PET study of 7 healthy human subjects, a high

  12. Psychopharmacological Treatment and Psychological Interventions in Irritable Bowel Syndrome

    Directory of Open Access Journals (Sweden)

    Emanuele Sinagra


    Full Text Available Irritable bowel syndrome (IBS accounts for 25% of gastroenterology output practice, making it one of the most common disorders in this practice. Psychological and social factors may affect the development of this chronic disorder. Furthermore, psychiatric symptoms and psychiatric diseases are highly prevalent in this condition, but the approach to treating these is not always straightforward. As emphasized in the biopsychosocial model of IBS, with regard to the modulatory role of stress-related brain-gut interactions and association of the disease with psychological factors and emotional state, it proves useful to encourage psychopharmacological treatments and psychosocial therapies, both aiming at reducing stress perception. The aim of this paper is to analyze the effectiveness of psychopharmacological treatment and psychological interventions on irritable bowel syndrome.


    Directory of Open Access Journals (Sweden)

    Silvia Anahí de la Mano


    Full Text Available The prevailing objective of this investigation has been study the psychologist’s value, in their professional practice, about the relation between the psychopharmacology and the psychopharmacotherapy. To purpose, a thirty psychologist sample, from both sexes has been used.Everybody inquiries, do their professional practice in the cities of General Pico and Santa Rosa, province of La Pampa. The participants congratulate the questionnaire to satisfy this study’s ending. The get on answers was compared about the central idea: a theoretical and technical orientation underlying the professional practice; and b training institution. The results suggest that there are statistically values of relationship between these variables: 1 theoretical and technical orientation underlying the professional practice / opinion about the psychopharmacotherapy; 2 theoretical and technical orientationunderlying the professional practice / interviewer’s sex; and 3 theoretical andtechnical orientation underlying the professional practice / opinion uponprofessional upgrade on psychopharmacology.

  14. Reflections on ethical issues in psychopharmacology: an American perspective. (United States)

    Gutheil, Thomas G


    Psychopharmacology has revolutionized psychiatric practice but raises a number of ethical issues. This review from an American perspective first describes ethics analyses and attempts to portray the ethical practitioner. Pressures that interfere with appropriate prescribing come from outside the prescriber and from within, including from insurers, other treatment staff and the prescriber's own will to act for the patient. Clinicians also face binds in which alternate choices seem to have merit and leave the prescriber feeling pulled in contradictory directions, frequently related to risk-benefit dilemmas. The ethics of psychopharmacology poses many questions that cannot yet be answered at the current state of the field. Pharmacology also seems to promote extremes of attitudes, such as "All such drugs are poisons" and the like. This review then provides some risk management principles, and concludes that such a review, though not comprehensive, may serve to open questions that are not always considered by clinicians. Copyright © 2012 Elsevier Ltd. All rights reserved.

  15. Improving the pedagogy associated with the teaching of psychopharmacology. (United States)

    Glick, Ira D; Salzman, Carl; Cohen, Bruce M; Klein, Donald F; Moutier, Christine; Nasrallah, Henry A; Ongur, Dost; Wang, Po; Zisook, Sidney


    The authors summarize two special sessions focused on the teaching of psychopharmacology at the 2003 and 2004 annual meeting of the American College of Neuropsychopharmacology (ACNP). The focus was on whether "improving the teaching-learning process" in psychiatric residency programs could improve clinical practice. Problems of strategies and pedagogic techniques that have been used were presented from multiple perspectives (e.g., from a dean, department chair, training director, and former students). There was a consensus that action involving psychopharmacology organizations and the American Association of Directors of Residency Training in Psychiatry (AADPRT) was necessary to improve "evidence-based" competencies before graduation and to follow prescribing patterns into clinical practice to determine whether the standards of care could be improved.



    Silvia Anahí de la Mano


    The prevailing objective of this investigation has been study the psychologist’s value, in their professional practice, about the relation between the psychopharmacology and the psychopharmacotherapy. To purpose, a thirty psychologist sample, from both sexes has been used.Everybody inquiries, do their professional practice in the cities of General Pico and Santa Rosa, province of La Pampa. The participants congratulate the questionnaire to satisfy this study’s ending. The get on answers was c...

  17. Teaching ethics of psychopharmacology research in psychiatric residency training programs. (United States)

    Beresin, Eugene V; Baldessarini, Ross J; Alpert, Jonathan; Rosenbaum, Jerrold


    American psychiatric residency training programs are now required to teach principles of research ethics. This task is especially pressing in light of evolving guidelines pertaining to human subjects, including psychiatric patients, especially when psychopharmacology is involved. Residents need to understand principles of research ethics and implications of roles of psychiatrists as investigators and clinicians. We consider major contemporary ethical issues in clinical psychiatric research, with an emphasis on psychopharmacology, and implications of addressing them within residency training programs. We reviewed recent literature on ethical issues in clinical research and on medical education in bioethics. This report considers: (1) an overview of current training; (2) perceived needs and rationales for training in research ethics, (3) recommended educational content and methods; (4) issues that require further study (including demonstration of acquired knowledge, practice issues, and the treatment versus-investigation misconception); and (5) conclusions. Recommended components of residency training programs include basic ethical principles; scientific merit and research design; assessment of risks and benefits; selection and informed consent of patient-subjects; and integrity of the clinical investigator, including definition of roles, conflicts-of-interest, and accountability. Evaluation of educational effectiveness for both trainees and faculty is a recommended component of such programs. We recommend that psychiatric training include education about ethical aspects of clinical research, with a particular emphasis on psychopharmacology. These activities can efficiently be incorporated into teaching of other aspects of bioethics, research methods, and psychopharmacology. Such education early in professional development should help to clarify roles of clinicians and investigators, improve the planning, conduct and reporting of research, and facilitate career

  18. Psychopharmacology of ADHD in pediatrics: current advances and issues


    Greydanus, Donald


    Donald E Greydanus, Ahsan Nazeer, Dilip R PatelMichigan State University College of Human Medicine, Michigan State University/Kalamazoo Center for Medical Studies, Kalamazoo, MI, USAAbstract: Attention deficit hyperactivity disorder (ADHD) is a neurobehavioral developmental disorder found in 3% to 8% of children and adolescents. An important part of ADHD management is psychopharmacology, which includes stimulants, norepinephrine reuptake inhibitors, alpha-2 agonists, and antidepressants. Medi...

  19. Contemporary ethical dilemmas in psychotherapy: cosmetic psychopharmacology and managed care. (United States)

    Sperry, L; Prosen, H


    Two contemporary ethical dilemmas facing psychotherapists have been noted and described: cosmetic psychopharmacology and the practice of psychotherapy in a managed care environment. Regarding cosmetic psychopharmacology: It was noted that whether a psychotherapist endorses the use of psychotropic agents for cosmetic purposes, such as self-transformation, seems to be a function of the severity of the client/patient symptoms as well as the psychotherapist's view of human nature and the human condition. However, recent research indicates that certain traits or reflections of the human condition, such as irritability, may actually be neurotransmitter deficiencies that are responsive not only to psychotropic agents but also to non-drug interventions. These findings add an additional dimension to discussions of the ethics of cosmetic psychopharmacology. Regarding psychotherapy in a managed care environment: Several ethical dilemmas, including confidentiality, were discussed. These dilemmas were outlined rather than analyzed in detail. Some of them will become major "thorns" of concern for the practice of psychotherapy. Others will be less consequential. Of critical concern is that limitations by managed care on the technique and optimal length of treatment of psychotherapy can conceivably lessen its efficacy for some patients and could possibly eliminate this powerful treatment procedure for others.

  20. Safeguarding children's rights in psychopharmacological research: ethical and legal issues. (United States)

    Kölch, Michael; Ludolph, Andrea G; Plener, Paul L; Fangerau, Heiner; Vitiello, Benedetto; Fegert, Joerg M


    Research on psychopharmacological treatment in children and adolescents is the subject of ongoing ethical discussion, as minors with mental disorders constitute a vulnerable patient group. Considering the important legislative changes in pediatric research over the past decade in both the US and Western Europe, there is a need to review recent developments in this area. Based on a systematic literature review, a hermeneutical analysis focusing the main issues of ethics in child and adolescent psychopharmacology is provided. Legal and regulatory aspects of psychopharmacological research in children are compared between the US and Europe. Relevant issues were informed assent and consent to research participation, minimal risk and burden of research, ethics of pharmacogenetics, research on "me-too" medications, and justice in global research. Additionally, the concern about undue influence of financial interests in research is also addressed. Incentives for the conduct of clinical trials with children comparable to those contained in US legislation are now provided in the EU. Research to develop "me-too" preparations may have no significant benefit for children, but can cause research burden and detract from clinically more important projects by utilizing limited investigator time and patient resources. Thus far, pharmacogenetic studies may bring more individualized treatment approaches into child psychiatry but they remain at present a promise for the future. Finally, the issues of avoiding undue influence from funders and conflicts of interest remain a prominent concern which can be solved by declaring conflicts and publishing all results of studies extensively.

  1. Psychopharmacology of Persistent Violence and Aggression. (United States)

    Meyer, Jonathan M; Cummings, Michael A; Proctor, George; Stahl, Stephen M


    Persistent violence not due to acute psychosis or mania can be managed only after appropriate characterization of the aggressive episodes (psychotic, impulsive, or predatory/planned/instrumental). The type of violence combined with the psychiatric diagnosis dictates the evidence-based pharmacologic approaches for psychotically motivated and impulsive aggression, whereas instrumental violence mandates forensic/behavioral strategies. For nonacute inpatients, schizophrenia spectrum disorders, traumatic brain injury, and dementia comprise the majority of individuals who are persistently aggressive, with impulsive actions the most common form of violence across all diagnoses. Neurobiological considerations combined with empirical data provide a comprehensive framework for systematic medication trials to manage persistently aggressive patients. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Design and implementation of a wireless (Bluetooth) four channel bio-instrumentation amplifier and digital data acquisition device with user-selectable gain, frequency, and driven reference. (United States)

    Cosmanescu, Alin; Miller, Benjamin; Magno, Terence; Ahmed, Assad; Kremenic, Ian


    A portable, multi-purpose Bio-instrumentation Amplifier and Data AcQuisition device (BADAQ) capable of measuring and transmitting EMG and EKG signals wirelessly via Bluetooth is designed and implemented. Common topologies for instrumentation amplifiers and filters are used and realized with commercially available, low-voltage, high precision operational amplifiers. An 8-bit PIC microcontroller performs 10-bit analog-to-digital conversion of the amplified and filtered signals and controls a Bluetooth transceiver capable of wirelessly transmitting the data to any Bluetooth enabled device. Electrical isolation between patient/subject, circuitry, and ancillary equipment is achieved by optocoupling components. The design focuses on simplicity, portability, and affordability.

  3. A National Survey of Graduate Education in Psychopharmacology: Advancing the Social Work Perspective on Psychiatric Medication (United States)

    Hughes, Shannon; Narendorf, Sarah; Lacasse, Jeffrey R.


    Social workers' unique skills and professional perspective can contribute to improved practices in psychopharmacology, yet it is unclear how social work programs prepare students for this area of practice. This study examined instruction of psychopharmacology through a national Web-based survey of MSW program directors and instructors of…

  4. Assessment of Psychopharmacology on the American Board of Psychiatry and Neurology Examinations (United States)

    Juul, Dorthea; Winstead, Daniel K.; Sheiber, Stephen C.


    OBJECTIVE: To report the assessment of psychopharmacology on the certification and recertification exams in general psychiatry and in the subspecialties administered by the American Board of Psychiatry and Neurology (ABPN). METHODS: The ABPN's core competencies for psychiatrists were reviewed. The number of items addressing psychopharmacology or…

  5. Name that neurotransmitter: using music to teach psychopharmacology concepts. (United States)

    Hermanns, Melinda; Lilly, Mary LuAnne; Wilson, Kathy; Russell, Nathan Andrew


    The purpose of this article is to discuss the use of music (i.e., two original songs, "Neurotransmitter Twitter" and "Parkinson's Shuffle") to teach aspects of psychopharmacology to students in the course Psychiatric/Mental Health Nursing. Songs were incorporated in both the clinical and classroom settings. This innovative teaching method allowed students the opportunity to revisit the information through multiple exposures of the content for reinforcement and enhancement of student learning in a fun, creative approach. Brain-based research will be discussed, along with the process of development. Copyright 2012, SLACK Incorporated.

  6. Evaluation of psychopharmacological effects of Clerodendrum phlomidis Linn. extract. (United States)

    Murugesan, T; Saravanan, K S; Lakshmi, S; Ramya, G; Thenmozhi, K


    The methanolic extract of Clerodendrum phlomidis Linn. (MECP) leaves was evaluated for its psychopharmacological activities in several experimental models using Swiss albino mice and Wistar albino rats. The MECP was found to cause significant reduction in spontaneous activity, and decreases in exploratory behavioral profiles by the Y-maze and head dip test. It also showed reduction in muscle relaxant activity by rotarod, 30 degrees inclined screen and traction tests, as well as significantly potentiated the phenobarbitone sodium-induced sleeping time in the doses examined (200, 400 and 600 mg/kg body wt.). All the results were compared with respective controls for the evaluation of significance.

  7. Minimisation of instrumental noise in the acquisition of FT-NIR spectra of bread wheat using experimental design and signal processing techniques. (United States)

    Foca, G; Ferrari, C; Sinelli, N; Mariotti, M; Lucisano, M; Caramanico, R; Ulrici, A


    Spectral resolution (R) and number of repeated scans (S) have a significant effect on the S/N ratio of Fourier transform-near infrared (FT-NIR) spectra, but the optimal values of these two parameters have to be determined empirically for a specific problem, considering separately both the nature of the analysed matrix and the specific instrumental setup. To achieve this aim, the instrumental noise of replicated FT-NIR spectra of wheat samples was modelled as a function of R and S by means of the Doehlert design. The noise amounts in correspondence to different experimental conditions were estimated by analysing the variance signals derived from replicate measurements with two different signal processing tools, Savitzky-Golay (SG) filtering and fast wavelet transform (FWT), in order to separate the "pure" instrumental noise from other variability sources, which are essentially connected to sample inhomogeneity. Results confirmed that R and S values leading to minimum instrumental noise can vary considerably depending on the type of analysed food matrix and on the different instrumental setups, and helped in the selection of the optimal measuring conditions for the subsequent acquisition of a wide spectral dataset.

  8. An Assessment of the Effectiveness of Air Force Risk Management Practices in Program Acquisition Using Survey Instrument Analysis (United States)


    the Defense Acquisition University (DAU) Program Management Tools ( PMT ) courses, PMT 251 and PMT 257. Those courses focus on program 37 management...Management PMI Project Management Institute PMT Program Management Tools RM Risk Management SE Systems Engineering TRL Technology Readiness...Information Operations and Reports (0704-0188), 1215 Jefferson Davis Highway, Suite 1204, Arlington, VA 22202-4302. Respondents should be aware that

  9. Acquisition system for the "EMSO Generic Instrument Module" (EGIM) and analysis of the data obtained during its first deployment at OBSEA site (Spain) (United States)

    Garcia, Oscar; Mihai Toma, Daniel; Dañobeitia, Juanjo; del Rio, Joaquin; Bartolome, Rafael; Martínez, Enoc; Nogueras, Marc; Bghiel, Ikram; Lanteri, Nadine; Rolin, Jean Francois; Beranzoli, Laura; Favali, Paolo


    The EMSODEV project (EMSO implementation and operation: DEVelopment of instrument module) is an Horizon-2020 UE project whose overall objective is the operation of eleven seafloor observatories and four test sites. These infrastructures are distributed throughout European seas, from the Arctic across the Atlantic and the Mediterranean to the Black Sea, and are managed by the European consortium EMSO-ERIC (European Research Infrastructure Consortium) with the participation of 8 European countries and other associated partners. Recently, we have implemented a Generic Sensor Module (EGIM) within the EMSO-ERIC distributed marine research infrastructure. EGIM is able to operate on any EMSO observatory node, mooring line, seabed station, cabled or non-cabled and surface buoy. The main role of EGIM is to measure homogeneously a set of core variables using the same hardware, sensor references, qualification methods, calibration methods, data format and access, maintenance procedures in several European ocean locations. The EGIM module acquires a wide range of ocean parameters in a long-term consistent, accurate and comparable manner from disciplines such as biology, geology, chemistry, physics, engineering, and computer science, from polar to subtropical environments, through the water column down to the deep sea. Our work includes developing standard-compliant generic software for Sensor Web Enablement (SWE) on EGIM and to perform the first onshore and offshore test bench, to support the sensors data acquisition on a new interoperable EGIM system. EGIM in its turn is linked to an acquisition drives processes, a centralized Sensor Observation Service (SOS) server and a laboratory monitor system (LabMonitor) that records events and alarms during acquisition. The measurements recorded along EMSO NODES are essential to accurately respond to the social and scientific challenges such as climate change, changes in marine ecosystems, and marine hazards. This presentation shows

  10. The ethics of clinical innovation in psychopharmacology: Challenging traditional bioethics

    Directory of Open Access Journals (Sweden)

    Goodwin Frederick K


    Full Text Available Abstract Objective To assess the scientific and ethical basis for clinical innovation in psychopharmacology. Methods We conducted a literature review, utilizing MEDLINE search and bibliographic cross-referencing, and historical evidence regarding the discovery and development of new medications in psychiatry. Clinical innovation was defined as use of treatments in a clinical setting which have not been well-proven in a research setting. Results Empirical data regarding the impact of clinical innovation in psychopharmacology are lacking. A conceptual and historical assessment of this topic highlights the ethical and scientific importance of clinical innovation. Ethically, it touches a borderline that, in our judgment, is not adequately framed in contemporary mainstream bioethics. Currently, research is viewed as not at all benefiting the patients who participate in it, while clinical care is viewed as being solely for the benefit of patients. Clinical innovation straddles these two worlds, uncomfortably at times. While many argue that clinical innovation should either be avoided or folded into research projects, we argue that clinical innovation is necessary for progress in psychopharmacology research, and that it can prosper best when guided by the following ethical principles: 1. The treatment should be based on a viable hypothesis. 2. Whenever possible, one's clinical observations should be reported so they can be evaluated by the scientific community. 3. One should be willing to report unexpected observations of drug effects. 4. A high standard of informed consent should be maintained. Again, this proposal goes against the standard view among bioethicists that research and clinical care are categorically opposed activities, as made clear by the either-or dichotomy of the Belmont Report on bioethics. This approach has so polarized our profession into clinicians versus researchers, that many clinicians will not apply new knowledge produced by

  11. Genetic Testing for Psychopharmacology: Is It Ready for Prime Time? (United States)

    Leahy, Laura G


    Genetic testing in psychiatric practice may be a beneficial adjunct to the nursing toolbox of considerations used to improve patient outcomes. Since 2004, the psychiatric community has used genotyping to personalize medication options for their patients. Although not a definitive or exact science, pharmacogenetic testing for psychopharmacological treatment options offers nurses and their patients insights into potential treatments that will reduce the current trial-and-error prescribing practices and more quickly improve patients' quality of life. The current article guides nurses through the process of conducting genetic testing, interpreting the results, and applying the results in clinical practice using a fictitious case example. [Journal of Psychosocial Nursing and Mental Health Services, 55(3), 19-23.]. Copyright 2017, SLACK Incorporated.

  12. Psychopharmacology of noncognitive abnormal behaviors in Alzheimer's disease. (United States)

    Raskind, M A


    Disruptive agitation and psychotic symptoms are important problems in the management of Alzheimer's disease and are major determinants of nursing home placement. This article reviews interpretable, placebo-controlled studies of psychopharmacologic approaches to the treatment of these "noncognitive" psychiatric and behavioral problems. Clinical trials of antipsychotic drugs demonstrate modest efficacy for psychosis and agitation, but adverse effects are common. Trials of serotonin selective reuptake inhibitors suggest they may be effective for emotional disturbances complicating Alzheimer's disease. Trials of drugs that enhance central cholinergic activity (certain cholinesterase inhibitors and selective M1 muscarinic cholinergic agonists) demonstrate positive effects on both cognitive deficits and noncognitive psychiatric and behavioral problems. Further clinical studies are needed to provide guidelines for the management of noncognitive psychiatric and behavioral problems in Alzheimer's disease.

  13. Acquisition of sorption isotherms for modified woods by the use of dynamic vapour sorption instrumentation. Principles and Practice

    DEFF Research Database (Denmark)

    Engelund, Emil Tang; Klamer, Morten; Venås, Thomas Mark


    depending on the number of data points required. The fast data acquisition makes DVS a useful tool in studying the sorption properties of wood, and especially in studying the effect of different modification treatments on these properties. This study includes an investigation of the sorption properties......The complex wood-water relationship has been the topic of numerous studies. Sorption isotherms – in particular – have been derived for hundreds of wood species, their sap- and heartwood sections as well as for decayed, engineered and modified wood materials. However, the traditional methods...... not commencing from full water saturation. The sorption properties of heat treated Scots pine (Celloc) and acetylated Radiata pine (Accoya) showed a greater hysteresis effect for the previous than both acetylated and untreated softwood. Furthermore, the effectiveness of the different modification treatments...

  14. Real-time operation without a real-time operating system for instrument control and data acquisition (United States)

    Klein, Randolf; Poglitsch, Albrecht; Fumi, Fabio; Geis, Norbert; Hamidouche, Murad; Hoenle, Rainer; Looney, Leslie; Raab, Walfried; Viehhauser, Werner


    We are building the Field-Imaging Far-Infrared Line Spectrometer (FIFI LS) for the US-German airborne observatory SOFIA. The detector read-out system is driven by a clock signal at a certain frequency. This signal has to be provided and all other sub-systems have to work synchronously to this clock. The data generated by the instrument has to be received by a computer in a timely manner. Usually these requirements are met with a real-time operating system (RTOS). In this presentation we want to show how we meet these demands differently avoiding the stiffness of an RTOS. Digital I/O-cards with a large buffer separate the asynchronous working computers and the synchronous working instrument. The advantage is that the data processing computers do not need to process the data in real-time. It is sufficient that the computer can process the incoming data stream on average. But since the data is read-in synchronously, problems of relating commands and responses (data) have to be solved: The data is arriving at a fixed rate. The receiving I/O-card buffers the data in its buffer until the computer can access it. To relate the data to commands sent previously, the data is tagged by counters in the read-out electronics. These counters count the system's heartbeat and signals derived from that. The heartbeat and control signals synchronous with the heartbeat are sent by an I/O-card working as pattern generator. Its buffer gets continously programmed with a pattern which is clocked out on the control lines. A counter in the I/O-card keeps track of the amount of pattern words clocked out. By reading this counter, the computer knows the state of the instrument or knows the meaning of the data that will arrive with a certain time-tag.

  15. Acquisition of a Modified Suction Casting Instrument for the Fabrication of Radiation Tolerant Bulk nNanostructured Metallic Materials (United States)


    microscope. Hardness and elastic modulus of the specimens were determined by using instrumented nanoindentation technique on a Fischerscope 2000XYp nano ...of Fe2Zr (Fig. 2, Fig. 3). As the thermal expansion coefficient ( TEC ) of Fe and Fe2Zr is different, thermal stress arises during in situ annealing...2), where t is the thermal mismatch strain, E is the Young’s modulus of Fe,  Fe and 2Fe Zr are the respective TEC of the -Fe and Fe2Zr

  16. Issues of academic study and practical acquisition of Tuvan music (a case study of Tuvan instrumental music

    Directory of Open Access Journals (Sweden)

    Valentina Yu. Suzukey


    Full Text Available In the 20th century, Tuvan music culture has undergone dramatic upheaval and a number of transformations. Today we face an acute need to rethink the achievements and losses incurred over that period of time. The objective of this article is to reconsider some basic parameters of Tuvan music culture that are responsible for preserving the integrity of its sound structure. The relevance of the topic is due to a current conceptual rift between the musical practices and their scholarly interpretations. In the Soviet period, culture throughout the entire USSR was solely driven by the European model of musical development with no reliance on practices typical for ethnical cultures. We are currently witnessing a decline in the numbers of those representing oral and audial traditional culture, while the numbers of music college graduates, those who studied at conservatoires, universities, academies of culture and arts, and thus come as bearers of values lying outside of the tradition. Tuvan musical practice is experiencing an invasion of academic vocabulary and non-relevant appraisal criteria. However, Tuvan musical culture, having always been primarily oral, has developed its own acoustic structure, as well as mechanisms and methods for non-scriptory transfer of knowledge. But these vernacular methods are still insufficiently explored. The author postulates that the system of Tuvan instrumental music organization is unique and acts as a basis for unconventional sound of musical instruments and xöömei (throat singing. Distinctive timbre and inimitable flair of the sound is achieved by original system of bourdon-overtone sound coordination. Music is created for audial enjoyment. But musicologists (mainly in Russia are still analyzing the notation they keep making of performed folk instrumental pieces and xöömei. Such an approach drastically narrows the entire panorama of traditional instrumental music. A positive factor is that contemporary Tuvan

  17. The Role of the Therapeutic Relationship in Psychopharmacological Treatment Outcomes: A Meta-analytic Review. (United States)

    Totura, Christine M Wienke; Fields, Sherecce A; Karver, Marc S


    Patient nonadherence to psychopharmacological treatment is a significant barrier to effective treatment. The therapeutic relationship is known to be a critical component of effective psychological treatment, but it has received limited study. A meta-analysis was conducted to examine the role of the therapeutic relationship in the delivery of effective psychopharmacological treatment. PubMed, PsycINFO, CINAHL, Google Scholar, Ingenta, and the Web of Science-Science Citation Index were searched, including reference lists of found articles. Meta-analytic methods were used to examine the association between the physician-patient therapeutic relationship and outcomes in psychopharmacological treatment. Eight independent studies of psychopharmacological treatment reported in nine articles met the inclusion criterion (1,065 participants) of being an empirically based study in which measures of the therapeutic relationship were administered and psychiatric treatment outcomes were assessed. The overall average weighted effect size for the association between the therapeutic relationship and treatment outcomes was z=.30 (95% confidence interval=.20-.39), demonstrating a statistically significant, moderate effect. Findings indicate that a positive therapeutic relationship or alliance between the physician and the psychiatric patient is associated with patient improvement over the course of psychopharmacological treatment. Results suggest that more attention should be paid to psychiatrist communication skills that may enhance the therapeutic alliance in psychopharmacological treatment.

  18. The psychopharmacological activities of Vietnamese ginseng in mice: characterization of its psychomotor, sedative–hypnotic, antistress, anxiolytic, and cognitive effects

    Directory of Open Access Journals (Sweden)

    Irene Joy I. dela Peña


    Conclusion: VG, like other ginseng products, has significant and potentially useful psychopharmacological effects. This includes, but is not limited to, psychomotor stimulation, anxiolytic, antistress, and memory enhancing effects.

  19. Sexual dimorphism and specificities of psychopharmacological treatment in women

    Directory of Open Access Journals (Sweden)

    Draganić-Gajić Saveta


    Full Text Available The scope of gender related differences observed in mentally ill persons provides a major source of inference about the role of gonadal steroids in brain function and behavior. Reported gender dimorphism in psychiatry includes the following: prevalence of certain mental disorders specific to female gender, phenomenology and treatment characteristics, i.e. response to the applied psychopharmacotherapy. Structural and functional relationship between the hormonal system and central nervous system is closely correlated with vulnerability to various psychopathological disturbances in biologically different stages in women. It has been observed, for instance, that the association of gonadal steroid activity with serotonin is relevant to mood change in premenstrual and postpartum mood disturbances. Gender related hormonal fluctuations may cause or be correlated with the development of several gender-related psychopathological disturbances. The aim of this article is to review the literature concerning gender-related specificities of psychopharmacological treatment of some of the most important mental disorders in women, such as affective disorder in menopause, premenstrual syndrome and postpartum mood disorders.

  20. The role of psychopharmacology in the medical abuses of the Third Reich: from euthanasia programmes to human experimentation. (United States)

    López-Muñoz, Francisco; Alamo, Cecilio; García-García, Pilar; Molina, Juan D; Rubio, Gabriel


    German psychiatry and pharmacology both enjoyed an extraordinary international reputation prior to the promulgation of the Third Reich. However, with the triumph of eugenic ideas and the imposition of a "racial hygiene" policy by the Nazi regime, various organs of the German health system saw themselves involved in a perverse system of social control, in which the illicit use of psychopharmacological tools became customary. In the present work, we review, from the historical perspective, the factors that helped to bring about this situation and we analyze the abuses (known and documented) committed through the specific use of psychotropic drugs during the Nazi period. Among such abuses we can identify the following illegitimate activities: the use of psychoactive drugs, mainly sedatives from the barbiturates family, in the different euthanasia programmes implemented by the Nazi authorities, in police activity and various types of repression, and for purely criminal and extermination purposes within the so-called "Final Solution"; psychopharmacological research on the mentally ill, without the slightest ethical requirements or legal justification; and the use of psychotropic agents in research on healthy subjects, recruited from concentration camps. Finally, we refer to the role of poisonous nerve agents (tabun, sarin and soman) as instruments of chemical warfare and their development by the German authorities. Many of these activities, though possibly only a small portion of the total - given the destruction of a great deal of documentation just before the end of World War II - came to light through the famous Nuremberg Trials, as well as through other trials in which specific persons were brought to justice unilaterally by individual Allied nations or by the authorities of the new German government after the War.

  1. Development of intelligent instruments with embedded HTTP servers for control and data acquisition in a cryogenic setup—The hardware, firmware, and software implementation

    Energy Technology Data Exchange (ETDEWEB)

    Antony, Joby; Mathuria, D. S.; Datta, T. S. [Inter University Accelerator Centre, Aruna Asaf Ali Marg, New Delhi 110067 (India); Maity, Tanmoy [Department of MME, Indian School of Mines (ISM), Dhanbad 826004 (India)


    The power of Ethernet for control and automation technology is being largely understood by the automation industry in recent times. Ethernet with HTTP (Hypertext Transfer Protocol) is one of the most widely accepted communication standards today. Ethernet is best known for being able to control through internet from anywhere in the globe. The Ethernet interface with built-in on-chip embedded servers ensures global connections for crate-less model of control and data acquisition systems which have several advantages over traditional crate-based control architectures for slow applications. This architecture will completely eliminate the use of any extra PLC (Programmable Logic Controller) or similar control hardware in any automation network as the control functions are firmware coded inside intelligent meters itself. Here, we describe the indigenously built project of a cryogenic control system built for linear accelerator at Inter University Accelerator Centre, known as “CADS,” which stands for “Complete Automation of Distribution System.” CADS deals with complete hardware, firmware, and software implementation of the automated linac cryogenic distribution system using many Ethernet based embedded cryogenic instruments developed in-house. Each instrument works as an intelligent meter called device-server which has the control functions and control loops built inside the firmware itself. Dedicated meters with built-in servers were designed out of ARM (Acorn RISC (Reduced Instruction Set Computer) Machine) and ATMEL processors and COTS (Commercially Off-the-Shelf) SMD (Surface Mount Devices) components, with analog sensor front-end and a digital back-end web server implementing remote procedure call over HTTP for digital control and readout functions. At present, 24 instruments which run 58 embedded servers inside, each specific to a particular type of sensor-actuator combination for closed loop operations, are now deployed and distributed across control LAN

  2. Development of intelligent instruments with embedded HTTP servers for control and data acquisition in a cryogenic setup—The hardware, firmware, and software implementation (United States)

    Antony, Joby; Mathuria, D. S.; Datta, T. S.; Maity, Tanmoy


    The power of Ethernet for control and automation technology is being largely understood by the automation industry in recent times. Ethernet with HTTP (Hypertext Transfer Protocol) is one of the most widely accepted communication standards today. Ethernet is best known for being able to control through internet from anywhere in the globe. The Ethernet interface with built-in on-chip embedded servers ensures global connections for crate-less model of control and data acquisition systems which have several advantages over traditional crate-based control architectures for slow applications. This architecture will completely eliminate the use of any extra PLC (Programmable Logic Controller) or similar control hardware in any automation network as the control functions are firmware coded inside intelligent meters itself. Here, we describe the indigenously built project of a cryogenic control system built for linear accelerator at Inter University Accelerator Centre, known as "CADS," which stands for "Complete Automation of Distribution System." CADS deals with complete hardware, firmware, and software implementation of the automated linac cryogenic distribution system using many Ethernet based embedded cryogenic instruments developed in-house. Each instrument works as an intelligent meter called device-server which has the control functions and control loops built inside the firmware itself. Dedicated meters with built-in servers were designed out of ARM (Acorn RISC (Reduced Instruction Set Computer) Machine) and ATMEL processors and COTS (Commercially Off-the-Shelf) SMD (Surface Mount Devices) components, with analog sensor front-end and a digital back-end web server implementing remote procedure call over HTTP for digital control and readout functions. At present, 24 instruments which run 58 embedded servers inside, each specific to a particular type of sensor-actuator combination for closed loop operations, are now deployed and distributed across control LAN (Local

  3. Development of intelligent instruments with embedded HTTP servers for control and data acquisition in a cryogenic setup--The hardware, firmware, and software implementation. (United States)

    Antony, Joby; Mathuria, D S; Datta, T S; Maity, Tanmoy


    The power of Ethernet for control and automation technology is being largely understood by the automation industry in recent times. Ethernet with HTTP (Hypertext Transfer Protocol) is one of the most widely accepted communication standards today. Ethernet is best known for being able to control through internet from anywhere in the globe. The Ethernet interface with built-in on-chip embedded servers ensures global connections for crate-less model of control and data acquisition systems which have several advantages over traditional crate-based control architectures for slow applications. This architecture will completely eliminate the use of any extra PLC (Programmable Logic Controller) or similar control hardware in any automation network as the control functions are firmware coded inside intelligent meters itself. Here, we describe the indigenously built project of a cryogenic control system built for linear accelerator at Inter University Accelerator Centre, known as "CADS," which stands for "Complete Automation of Distribution System." CADS deals with complete hardware, firmware, and software implementation of the automated linac cryogenic distribution system using many Ethernet based embedded cryogenic instruments developed in-house. Each instrument works as an intelligent meter called device-server which has the control functions and control loops built inside the firmware itself. Dedicated meters with built-in servers were designed out of ARM (Acorn RISC (Reduced Instruction Set Computer) Machine) and ATMEL processors and COTS (Commercially Off-the-Shelf) SMD (Surface Mount Devices) components, with analog sensor front-end and a digital back-end web server implementing remote procedure call over HTTP for digital control and readout functions. At present, 24 instruments which run 58 embedded servers inside, each specific to a particular type of sensor-actuator combination for closed loop operations, are now deployed and distributed across control LAN (Local

  4. A bibliometric analysis of research in psychopharmacology by psychology departments (1987-2007). (United States)

    Portillo-Salido, Enrique F


    From the very outset of scientific Psychology, psychologists have shown interest for drugs and their effects on behavior. This has given rise to numerous contributions, mostly in the form of Psychopharmacology publications. The aim of this study was to quantitatively evaluate these contributions and compare them with other academic disciplines related to Psychopharmacology. Using the PubMed database, we retrieved information about articles from 15 journals included in the Pharmacology and Pharmacy category of the Journal Citation Reports database for a 21-year period (1987 to 2007). There were 37540 articles which about 52% were represented by 3 journals. About 70% of psychology publications were represented by 2 of these journals. Psychology departments accounted for the 11% of the published papers, which places Psychology third behind Psychiatry and Pharmacology, which contributed to 22.69 and 13% respectively. Psychology contributed to the greatest number of studies in 3 journals, second in 3 and third in 8. This report represents the first effort to explore the contribution of academic Psychology to the multidisciplinary science of psychopharmacology. Although leaders of production of psychopharmacology research were from Psychiatry and Pharmacology, Psychology departments are an important source of studies and thus of knowledge in the field of Psychopharmacology.

  5. Psychopharmacological prescriptions for people with autism spectrum disorder (ASD): a multinational study

    NARCIS (Netherlands)

    Hsia, Y.; Wong, A.Y.; Murphy, D.G.; Simonoff, E.; Buitelaar, J.K.; Wong, I.C.


    RATIONALE: Previous studies on psychotropic drugs prescribing in autism spectrum disorder (ASD) were from the USA or the UK. However, these studies may not be generalizable to other countries. There is a need to understand the extent of psychopharmacological prescribing for ASD treatment at a

  6. The Role of the Pharmaceutical Industry in Teaching Psychopharmacology: A Growing Problem (United States)

    Brodkey, Amy C.


    OBJECTIVE: To describe and examine the role of the pharmaceutical industry in the teaching of psychopharmacology to residents and medical students and to make recommendations for changes in curriculum and policy based on these findings. METHODS: Literature reviews and discussions with experts, educators, and trainees. RESULTS: The pharmaceutical…

  7. The following abstracts were presented as posters at the 2016 NEI Psychopharmacology Congress. (United States)


    Congratulations to the scientific poster winners of the 2016 NEI Psychopharmacology Congress! 1 st Place: A Case Report and Literature Review of Clozapine Re-challenge Titration Schedules (page 26) 2 nd Place: Mental Health Statistics and Suicide Prevention at St. Tammany Parish Jail-2015 (page 41) 3 rd Place: Lithium-Induced Neurotoxicity at Therapeutic Range: Illustrative Cases and Literature Review (page 43).

  8. Mental Health Issues among College Students: Who Gets Referred for Psychopharmacology Evaluation? (United States)

    Kirsch, Daniel J.; Doerfler, Leonard A.; Truong, Debbie


    Objective: To describe diagnostic and psychotropic medication prescription characteristics among college students referred by college counseling centers for psychopharmacologic evaluation. Participants: Participants were 540 college students referred by 6 college counseling centers in Massachusetts between November 2005 and May 2011. Methods:…

  9. Psychopharmacological boundaries of schizophrenia with comorbid cannabis use disorder: a critical review. (United States)

    Lazary, Judit


    Although cannabis use disorder is strongly related to schizophrenia and treatment of patients with double diagnosis provides serious problem, specific pharmacological, molecular and therapeutical data on this subgroup are poorly available. In this paper we present a critical review on psychopharmacological boundaries of schizophrenia with concurrent cannabis use. The relevant data available in the literature suggest that a weaker compliance, poorer therapy response and higher sensitivity for extrapyramidal side effects are key features of schizophrenia and comorbid cannabis use disorder and represent a clinical challenge. Because of paucity of available research in the field there is not enough evidence to clearly depict the exact psychopharmacological profile of cannabis related schizophrenia. Further investigations are needed to assess phenotypic characteristics of this entity and to tailor effective treatment options accordingly.

  10. Psychopharmacological Effects of Alkaloid Z77 under Conditions of Posthypoxic Encephalopathy and Mechanisms of Their Development. (United States)

    Zyuz'kov, G N; Losev, E A; Chaikovskii, A V; Suslov, N I; Zhdanov, V V; Udut, E V; Miroshnichenko, L A; Simanina, E V; Polyakova, T Yu; Povet'eva, T N; Nesterova, Yu V; Stavrova, L A; Udut, V V; Minakova, M Yu; Dygai, A M


    Psychopharmacological effects of atisine-type diterpene alkaloid Z77 were studied under conditions of experimental posthypoxic encephalopathy. The preparation had a pronounced cerebroprotective effect consisting in normalization of orientation and exploratory behavior and conditioned activity in experimental animals. These changes were accompanied by significant increase in the number of neural stem cells in the paraventricular region of the brain and markedly enhanced production of neurotrophic growth factors by neural tissue microenvironment cells.

  11. The Intimate Geographies of Panic Disorder: Parsing Anxiety through Psychopharmacological Dissection. (United States)

    Callard, Felicity


    The category of panic disorder was significantly indebted to early psychopharmacological experiments (in the late 1950s and early 1960s) by the psychiatrist Donald Klein, in collaboration with Max Fink. Klein's technique of "psychopharmacological dissection" underpinned his transformation of clinical accounts of anxiety and was central in effecting the shift from agoraphobic anxiety (with its spatial imaginary of city squares and streets) to panic. This technique disaggregated the previously unitary affect of anxiety-as advanced in psychoanalytic accounts-into two physiological and phenomenological kinds. "Psychopharmacological dissection" depended on particular modes of clinical observation to assess drug action and to interpret patient behavior. The "intimate geographies" out of which panic disorder emerged comprised both the socio-spatial dynamics of observation on the psychiatric ward and Klein's use of John Bowlby's model of separation anxiety-as it played out between the dyad of infant and mother-to interpret his adult patients' affectively disordered behavior. This essay, in offering a historical geography of mid-twentieth-century anxiety and panic, emphasizes the importance of socio-spatial setting in understanding how clinical and scientific experimentation opens up new ways in which affects can be expressed, shaped, observed, and understood.

  12. Factors influencing adherence to psychopharmacological medications in psychiatric patients: a structural equation modeling approach

    Directory of Open Access Journals (Sweden)

    De las Cuevas C


    Full Text Available Carlos De las Cuevas,1 Jose de Leon,2–4 Wenceslao Peñate,5 Moisés Betancort5 1Departamento de Medicina Interna, Dermatología y Psiquiatría, Universidad de La Laguna, Canary Islands, Spain; 2Mental Health Research Center at Eastern State Hospital, Lexington, KY, USA; 3Psychiatry and Neurosciences Research Group (CTS-549, Institute of Neurosciences, University of Granada, Granada, Spain; 4Biomedical Research Center in Mental Health Net (CIBERSAM, Santiago Apostol Hospital, University of the Basque Country, Vitoria, Spain; 5Departamento de Psicología Clínica, Psicobiología y Metodología, Universidad de La Laguna, Canary Islands, Spain Purpose: To evaluate pathways through which sociodemographic, clinical, attitudinal, and perceived health control variables impact psychiatric patients’ adherence to psychopharmacological medications.Method: A sample of 966 consecutive psychiatric outpatients was studied. The variables were sociodemographic (age, gender, and education, clinical (diagnoses, drug treatment, and treatment duration, attitudinal (attitudes toward psychopharmacological medication and preferences regarding participation in decision-making, perception of control over health (health locus of control, self-efficacy, and psychological reactance, and level of adherence to psychopharmacological medications. Structural equation modeling was applied to examine the nonstraightforward relationships and the interactive effects among the analyzed variables.Results: Structural equation modeling demonstrated that psychiatric patients’ treatment adherence was associated: 1 negatively with cognitive psychological reactance (adherence decreased as cognitive psychological reactance increased, 2 positively with patients’ trust in their psychiatrists (doctors’ subscale, 3 negatively with patients’ belief that they are in control of their mental health and that their mental health depends on their own actions (internal subscale, and 4

  13. Liquid chromatography, in combination with a quadrupole time-of-flight instrument, with sequential window acquisition of all theoretical fragment-ion spectra acquisition: validated quantification of 39 antidepressants in whole blood as part of a simultaneous screening and quantification procedure. (United States)

    Roemmelt, Andreas T; Steuer, Andrea E; Kraemer, Thomas


    Sequential window acquisition of all theoretical fragment ion spectra (SWATH) is a data independent acquisition (DIA) method for very fast scanning quadrupole time-of-flight (QTOF) instruments. SWATH repeatedly cycles through 28 consecutive 20 Da precursor isolation windows detecting all precursor ions and fragments MS ALL like and yet fast enough to generate more than 10 data points over the chromatographic peak. It was already shown in previous publications that SWATH, despite its wide Q1 windows, allows the identification of different substances and that SWATH has a higher identification rate than data dependent acquisition approaches. The aim of this study was a proof of concept study whether these same data sets can also enable validated quantification according to international guidelines, exemplified for 39 antidepressants. The validation included recovery, matrix effects, process efficiency, ion suppression, and enhancement of coeluting ions, selectivity, accuracy, precision, and stability. The method using SWATH acquisition proved to be selective, sensitive, accurate, and precise enough for 33 out of the 39 antidepressants. The applicability of SWATH for screening and validated quantification in the same run was successfully tested with authentic whole blood samples containing different antidepressants and other drugs thus proving the QUAL/QUAN abilities of SWATH. In an additional systematic investigation, it could be shown that calibration curves injected a few days after or before the actual sample can be used for quantification with acceptable accuracy.

  14. Bipolarity and inadequate response to antidepressant drugs: clinical and psychopharmacological perspective. (United States)

    Rybakowski, Janusz K


    The reason why depression may respond poorly to treatment with antidepressant drugs may be connected with the features of bipolarity. Evidence to this effect has accumulated in recent studies of various kinds of depression in mood disorders. Additional evidence for such a connection may be the efficacy of mood-stabilizing drugs in the augmentation of antidepressants in treatment-resistant depression. This review is based on clinical and psychopharmacological research performed over the past five years. The clinical investigation was based on the response to antidepressants of bipolar depression or to symptoms of hypomania, assessed mainly by the Mood Disorder Questionnaire (MDQ) and the Hypomania Checklist-32 (HCL-32). The psychopharmacological research tested the efficacy of augmentation of antidepressants in treatment-resistant depression by mood-stabilizing drugs of the 1st and 2nd generations. A number of studies have pointed to an association between bipolar depression, or symptoms of hypomania and an inadequate response to antidepressants. Such a connection was also found in the Polish TRES-DEP study which included 1051 depressed patients. Pharmacological studies have demonstrated the efficacy of first generation mood-stabilizing drugs (lithium, carbamazepine) and second generation drugs (quetiapine, olanzapine, risperidone, ziprasidone, lamotrigine) for augmentation of antidepressants in treatment-resistant depression. Some evidence has been presented that mixed depressive episodes may also belong to this category. The results of these clinical and psychopharmacological studies appear to confirm an association between bipolarity and a poor response of depression to treatment with antidepressant drugs. Copyright © 2011 Elsevier B.V. All rights reserved.

  15. Ziziphus spinosa seeds for insomnia: A review of chemistry and psychopharmacology. (United States)

    Shergis, Johannah Linda; Ni, Xiaojia; Sarris, Jerome; Zhang, Anthony Lin; Guo, Xinfeng; Xue, Charlie C; Lu, Chuanjian; Hugel, Helmut


    In Chinese medicine, Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou is widely used for the treatment of insomnia. This paper summarises the chemistry, psychopharmacology, and compares the pharmaceutical effects of the seeds of Ziziphus jujuba plant, Ziziphus spinosa (ZS) seeds, with benzodiazepines. Whole extracts and constituent compounds have been evaluated in preclinical and clinical studies. ZS secondary metabolites modulate GABAergic activity and the serotonergic system. The actual therapeutic agents require further confirmation/identification so that new insomnia phytomedicines can be discovered. Copyright © 2017 Elsevier GmbH. All rights reserved.

  16. Molecular properties of psychopharmacological drugs determining non-competitive inhibition of 5-HT3A receptors. (United States)

    Kornhuber, Johannes; Terfloth, Lothar; Bleich, Stefan; Wiltfang, Jens; Rupprecht, Rainer


    We developed a structure-property-activity relationship (SPAR)-model for psychopharmacological drugs acting as non-competitive 5-HT(3A) receptor antagonists by using a decision-tree learner provided by the RapidMiner machine learning tool. A single molecular descriptor, namely the molecular dipole moment per molecular weight (mu/MW), predicts whether or not a substance non-competitively antagonizes 5-HT-induced Na(+) currents. A low mu/MW is compatible with drug-cumulation in apolar lipid rafts. This study confirms that size-intensive descriptors allow the development of compact SPAR models.

  17. An instrument for fast acquisition of fluorescence decay curves at picosecond resolution designed for "double kinetics" experiments: application to fluorescence resonance excitation energy transfer study of protein folding. (United States)

    Ishay, Eldad Ben; Hazan, Gershon; Rahamim, Gil; Amir, Dan; Haas, Elisha


    The information obtained by studying fluorescence decay of labeled biopolymers is a major resource for understanding the dynamics of their conformations and interactions. The lifetime of the excited states of probes attached to macromolecules is in the nanosecond time regime, and hence, a series of snapshot decay curves of such probes might - in principle - yield details of fast changes of ensembles of labeled molecules down to sub-microsecond time resolution. Hence, a major current challenge is the development of instruments for the low noise detection of fluorescence decay curves within the shortest possible time intervals. Here, we report the development of an instrument, picosecond double kinetics apparatus, that enables recording of multiple fluorescence decay curves with picosecond excitation pulses over wide spectral range during microsecond data collection for each curve. The design is based on recording and averaging multiphoton pulses of fluorescence decay using a fast 13 GHz oscilloscope during microsecond time intervals at selected time points over the course of a chemical reaction or conformational transition. We tested this instrument in a double kinetics experiment using reference probes (N-acetyl-tryptophanamide). Very low stochastic noise level was attained, and reliable multi-parameter analysis such as derivation of distance distributions from time resolved FRET (fluorescence resonance excitation energy transfer) measurements was achieved. The advantage of the pulse recording and averaging approach used here relative to double kinetics methods based on the established time correlated single photon counting method, is that in the pulse recording approach, averaging of substantially fewer kinetic experiments is sufficient for obtaining the data. This results in a major reduction in the consumption of labeled samples, which in many cases, enables the performance of important experiments that were not previously feasible.

  18. Issues in the psychopharmacologic assessment and treatment of the orthodox Jewish patient. (United States)

    Feinberg, S Shalom


    As with members of other cultural and religious groups, patients within the Orthodox Jewish community present with their own distinct clinical psychiatric issues related to their unique beliefs and practices. This article reviews the existing literature and anecdotal experience on the psychopharmacologic assessment and treatment of Orthodox Jewish patients. Specific aspects examined include this group's perceived intense stigma in receiving treatment, the priority this community places on cognitive functioning, and how the influence of Jewish laws on marriage and sexual practices impacts one's treatment decisions. The relevance of Jewish dietary laws, the Sabbath, and the community's interest in alternative treatments are also discussed. The limited ethno-psychopharmacology research related to Orthodox Jewish psychiatric patients is reviewed. We conclude that understanding issues such as these is critical if one is going to work within this cultural system in order to successfully address their mental health issues. However, the dearth of controlled research in this community needs to be addressed to provide more effective treatment.

  19. A guide to psychopharmacological treatment of patients with intellectual disability in psychiatry. (United States)

    Molina-Ruiz, Rosa M; Martín-Carballeda, Julia; Asensio-Moreno, Inmaculada; Montañés-Rada, Francisco


    Background Subjects with intellectual disability are at increased risk of having comorbid psychiatric disorders and worse response to psychotherapeutic and psychopharmacological treatment interventions. On the other hand, available data on best treatment approach in this population are scarce and lack scientific evidence due to methodological limitations. The present study aims to perform a systematic review of the literature to facilitate the use of psychotropic drugs in clinical practice and better establish future research targets in this field. Objectives To review the available psychopharmacological strategies for patients with intellectual disabilities, psychiatric disorders, and behavioural disturbances. Serve as a quick guide for clinicians working in the field of intellectual disability. Methods We conducted a selective evidence-based review of the literature using Pubmed and EMBASE databases and selected most recent and relevant papers for this review. Results There are several available psychotropic drugs for the treatment of patients with intellectual disability and comorbid psychiatric disorders, although scientific evidence is limited. Treatment should be individualized according to risk-benefit balance. Discussion Further studies are needed and new available drugs should be considered to gain knowledge in effectiveness of different therapeutic approaches available in this population.

  20. Acquisition of Airborne Sea Ice Remote Sensing Data with CULPIS-X: an Instrument Mounted on a US Coast Guard C-130 (United States)

    Tschudi, M. A.; Tooth, M.; Barton-Grimley, R. A.


    To obtain high-resolution observations of sea ice, we developed the University of Colorado LIDAR Profiler Instrument Suite - Extended (CULPIS-X). CULPIS-X, originally funded by NASA and currently supported by ONR, is being deployed in the flare tube of a US Coast Guard (USCG) C-130 aircraft, during Arctic Domain Awareness (ADA) flights from Kodiak, AK to the Arctic, in cooperation with the Coast Guard and with the Seasonal Ice Zone Remote Sensing (SIZRS, J. Morrison, PI) program. CULPIS-X (Figure 1) contains a LIDAR, digital camera, thermal infrared and hyperspectral radiometers, along with a GPS for aircraft altitude and an Inertial Measurement Unit (IMU) for aircraft attitude, and a computer to process and write the instrument data to SD cards. The package is designed to fly over Arctic sea ice for the purposes of measuring sea ice roughness, estimating sea ice thickness, and measuring ice surface temperature and reflectance. CULPIS-X had its inaugural flight aboard a C-130 out of USCG Air Station Sacramento in April 2016. This flight tested the structure of CULPIS-X, along with instrument readiness. The inaugural Arctic flight of CULPIS-X took place on June 15, 2016. The C-130 took off from Kodiak and flew towards Deadhorse, where it turned on to the 150W longitude line and proceeded north to 76N. The C-130 descended to a lower altitude ( 500 feet) during several flight segments along the 150W line, from Deadhorse to 76N and back. The lower altitude is required to obtain ULS LIDAR return pulses as they reflect off the ocean and sea ice. A similar flight was also performed on July 13, 2016. LIDAR data will be utilized to determine the surface roughness of the overflown ice pack. Furthermore, we will pick locations where open water occurred near or within the ice pack, to establish the freeboard of the ice pack, which will be used to estimate the sea ice thickness. More flights are scheduled for this season, in mid-Aug, Sept, and Oct, and are designed to overfly

  1. Evidence-based guidelines for the pharmacological treatment of anxiety disorders : recommendations from the British Association for Psychopharmacology

    NARCIS (Netherlands)

    Baldwin, DS; Anderson, IM; Nutt, DJ; Bandelow, B; Bond, A; Davidson, JRT; den Boer, JA; Fineberg, NA; Knapp, M; Scott, J; Wittchen, HU


    These British Association for Psychopharmacology guidelines cover the range and aims of treatment for anxiety disorders. They are based explicitly on the available evidence and are presented as recommendations to aid clinical decision making in primary and secondary medical care. They may also serve

  2. Integration of Full Tensor Gravity and Z-Axis Tipper Electromagnetic Passive Low Frequency EM Instruments for Simultaneous Data Acquisition - Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Wieberg, Scott [Bell Geospace, Inc., Houston, TX (United States)


    Ground gravity is a common and useful tool for geothermal exploration. Gravity surveys map density changes in the subsurface that may be caused by tectonic deformation such as faulting, fracturing, plutonism, volcanism, hydrothermal alteration, etc. Full Tensor Gravity Gradient (FTG) data has been used for over a decade in both petroleum and mining exploration to map changes in density associated with geologic structure. Measuring the gravity gradient, rather than the gravity field, provides significantly higher resolution data. Modeling studies have shown FTG data to be a viable tool for geothermal exploration, but no FTG data had been acquired for geothermal applications to date. Electromagnetic methods have been used for geothermal exploration for some time. The Z-Axis Tipper Electromagnetic (ZTEM) was a newer technology that had found success in mapping deep conductivity changes for mining applications. ZTEM had also been used in limited tests for geothermal exploration. This newer technology provided the ability to cost effectively map large areas whilst detailing the electrical properties of the geological structures at depths. The ZTEM is passive and it uses naturally occurring audio frequency magnetic (AFMAG) signals as the electromagnetic triggering source. These geophysical methods were to be tested over a known geothermal site to determine whether or not the data provided the information required for accurately interpreting the subsurface geologic structure associated with a geothermal deposit. After successful acquisition and analysis of the known source area, an additional survey of a “greenfield” area was to be completed. The final step was to develop a combined interpretation model and determine if the combination produced a higher confident geophysical model compared to models developed using each of the technologies individually.

  3. [The psychopharmacological treatment of depressive disorders in childhood and adolescence - developments and standards since the «black box» warning]. (United States)

    Plener, Paul L; Fegert, Jörg M; Kölch, Michael G


    Depending on symptom severity, psychopharmacological treatment can be a valuable option in the treatment of depressive disorders in childhood and adolescence. This review provides recommendations for clinical treatment, focusing on suicidality and treatment-resistant patients. The quality of studies regarding the psychopharmacological therapy of depressive disorders in childhood and adolescence has improved since the «black box» warning of the FDA concerning the occurrence of suicidality under treatment with selective serotonin reuptake inhibitors (SSRIs). In Germany, there is proof for a trend toward a more evidence-based psychopharmacological treatment approach within recent years.

  4. Mechanisms of psychopharmacological effects of alkaloid Z77 under conditions of brain ischemia. (United States)

    Zyuz'kov, G N; Suslov, N I; Losev, E A; Zhdanov, V V; Udut, E V; Miroshnichenko, L A; Simanina, E V; Povet'eva, T N; Nesterova, Yu V; Udut, V V; Minakova, M Yu; Zamoshchina, T A; Dygai, A M


    We studied the psychopharmacological effects of atisine-type diterpene alkaloid Z77 in a rat model of brain ischemia in the morning and at night. The type of developing locomotor disorders in animals was shown to depend on circadian rhythms. Administration of Z77 substantially corrected manifestations of psychoneurological symptoms. The parameters of orientation and exploratory behavior and conditioned reflex activity were normalized. The key role of receptors of neural stem cells to fibroblast growth factor in the realization of their growth potential under the influence of the alkaloid was demonstrated. Under in vitro conditions, antibodies to fibroblast growth factor receptor abolished the increase in the number of neural CFU caused by Z77 in the culture of intact cells from the paraventricular region of the brain.

  5. Can psychopharmacological treatment change personality traits in patients with panic disorder? (United States)

    Kipper, Letícia; Wachleski, Cláudia; Salum, Giovanni Abrahão; Heldt, Elizeth; Blaya, Carolina; Manfro, Gisele Gus


    The aim of this study was to evaluate the effects that a particular psychopharmacological treatment has on personality patterns in patients with panic disorder. Forty-seven patients with panic disorder and 40 controls were included in the study. The Mini International Neuropsychiatric Interview and Minnesota Multiphasic Personality Inventory were used to assess Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, diagnoses and personality traits, respectively. Patients were treated with sertraline for 16 weeks. There was a significant decrease in the score on 8 of the 10 Minnesota Multiphasic Personality Inventory scales. In addition, neurotic triad and psychasthenia personality scores were higher among panic disorder patients, even during the posttreatment asymptomatic phase, than among controls. In the asymptomatic phase of the disease, panic disorder patients present a particular neurotic/anxious personality pattern. This pattern, although altered in the presence of acute symptoms, could be a focus of research.

  6. [Psychopharmacological drugs and ethiopathogenic theories in psychiatry. From discovery context to epistemological obstacle]. (United States)

    Wikinski, Silvia


    This work postulates the thesis that the development of the contemporary psychopharmacology, which began with the chemical changes imposed to molecules with antihistaminergic properties, modelled the current ethiopatogenic theories of mental diseases. The development of chlorpromazine and imipramine was coincident with the beginning of the research about neurotransmission. This coincidence contributed for the construction of the dopaminergic theory of schizophrenia and in the monoaminergic theory of depression. Limitations of the effectivity of current drugs, as observed in the trials CATIE and STAR-D may justify a change of perspective in the search for new molecular targets for the treatment of both diseases. Historical data are provided to illustrate the above mentioned thesis, in the perspective of two epistemological concepts: the context of discovery proposed by Hans Reichenbach and the epistemological obstacle, proposed by Gaston Bachelard.

  7. Psychopharmacologic treatment and blood transfusion in fast-track total hip and knee arthroplasty

    DEFF Research Database (Denmark)

    Gylvin, Silas Hinsch; Jørgensen, Christoffer Calov; Fink-Jensen, Anders


    transfusion databases and The Danish National Database of Reimbursed Prescriptions for information regarding blood transfusions and psychopharmacologic treatment. All participating orthopedic centers followed similar perioperative guidelines. Multiple logistic regression analysis was applied to calculate odds...... ratios (ORs) for transfusion between preoperative users and nonusers of psychotropics. RESULTS Of 8402 patients, 569 (6.8%) were SSRI users versus 7833 (93.2%) nonusers. A total of 109 (19,2%) patients in the SSRI group and 700 (8.9%) in the “no-SSRI” group received blood intra- or postoperatively.......79-6.13). Singular use of antipsychotics (APs) increased the transfusion risk (OR, 2.37; 95% CI, 1.04-2.41), while AP medicine in combination with antidepressants did not. CONCLUSIONS Preoperative treatment with SSRIs, OAs, or APs are independent risk factors for blood transfusion in elective fast-track THA and TKA....

  8. Instrumentation Automation for Concrete Structures. Report 4. Demonstration of Instrumentation Automation Techniques at Beaver Dam, Eureka Springs, Arkansas (United States)


    and Rehabilitation (REMR) reports entitled ’Instrumentation Automation for Concrete Structures .’ As a demonstration installation of the instruments...instrumentation for older concrete structures . Improvement of data acquisition instrumentation and implementation of the benefits of these improvements was of our concrete structures . Keywords: Computers, Crack measurement, Dam safety, Data acquisition, Installation techniques, Instrumentation automation.

  9. The variation of psychopharmacological prescription rates for people with autism spectrum disorder (ASD) in 30 countries. (United States)

    Wong, Angel Y S; Hsia, Yingfen; Chan, Esther W; Murphy, Declan G M; Simonoff, Emily; Buitelaar, Jan K; Wong, Ian C K


    There is significant variation in prescriptions among countries in clinical practice for the treatment of comorbidities associated with autism spectrum disorder (ASD). It has been suggested that many people with mental health disorders in low-/middle-income countries do not receive adequate treatment. Hence, this study investigated psychopharmacological treatment patterns for ASD comorbidities in 30 countries and the association between country's income and prescription rates. The IMS Prescribing Insights database was used to investigate prescription patterns for ASD comorbidity treatment from 2007 to 2012. Data were obtained from 30 countries in continents of Europe, Asia, Oceania, Central America, South America, and Africa. The gross domestic product (GDP) per capita was used as a proxy for each country's income. Spearman correlation was used to examine the association between prescription rate and GDP per capita. The highest prescription rates were found in Western Europe (3.89-36.36/10,000) while the lowest prescription rates were found in Asian countries, such as Turkey, Indonesia, Saudi Arabia, and Pakistan (0.04-0.82/10,000). The most commonly prescribed drug for ASD comorbidity treatment in most of the countries was risperidone, but antidepressants and antiepileptic drugs were also frequently prescribed. There was a significant positive correlation between GDP per capita and prescription rate (Spearman ρ = 0.60; P = 0.0011; 95% confidence interval 0.27-0.81), that is, the higher the GDP per capita, the higher the prescription rate. There are marked international differences in prescription rates, and this is partially accounted by economic factors. Future research should combine more data for ASD comorbidity treatment to explore the disparity of psychopharmacological treatment between countries. © 2014 International Society for Autism Research, Wiley Periodicals, Inc.

  10. Uma interface lab-made para aquisição de sinais analógicos instrumentais via porta paralela do microcomputador A lab-made interface for acquisition of instrumental analog signals at the parallel port of a microcomputer

    Directory of Open Access Journals (Sweden)

    Edvaldo da Nóbrega Gaião


    Full Text Available A lab-made interface for acquisition of instrumental analog signals between 0 and 5 V at a frequency up to 670 kHz at the parallel port of a microcomputer is described. Since it uses few and small components, it was built into the connector of a printer parallel cable. Its performance was evaluated by monitoring the signals of four different instruments and similar analytical curves were obtained with the interface and from readings from the instrument' displays. Because the components are cheap (~U$35,00 and easy to get, the proposed interface is a simple and economical alternative for data acquisition in small laboratories for routine work, research and teaching.

  11. Changes in clinical trials methodology over time: a systematic review of six decades of research in psychopharmacology.

    Directory of Open Access Journals (Sweden)

    André R Brunoni


    Full Text Available There have been many changes in clinical trials methodology since the introduction of lithium and the beginning of the modern era of psychopharmacology in 1949. The nature and importance of these changes have not been fully addressed to date. As methodological flaws in trials can lead to false-negative or false-positive results, the objective of our study was to evaluate the impact of methodological changes in psychopharmacology clinical research over the past 60 years.We performed a systematic review from 1949 to 2009 on MEDLINE and Web of Science electronic databases, and a hand search of high impact journals on studies of seven major drugs (chlorpromazine, clozapine, risperidone, lithium, fluoxetine and lamotrigine. All controlled studies published 100 months after the first trial were included. Ninety-one studies met our inclusion criteria. We analyzed the major changes in abstract reporting, study design, participants' assessment and enrollment, methodology and statistical analysis. Our results showed that the methodology of psychiatric clinical trials changed substantially, with quality gains in abstract reporting, results reporting, and statistical methodology. Recent trials use more informed consent, periods of washout, intention-to-treat approach and parametric tests. Placebo use remains high and unchanged over time.Clinical trial quality of psychopharmacological studies has changed significantly in most of the aspects we analyzed. There was significant improvement in quality reporting and internal validity. These changes have increased study efficiency; however, there is room for improvement in some aspects such as rating scales, diagnostic criteria and better trial reporting. Therefore, despite the advancements observed, there are still several areas that can be improved in psychopharmacology clinical trials.

  12. Changes in clinical trials methodology over time: a systematic review of six decades of research in psychopharmacology. (United States)

    Brunoni, André R; Tadini, Laura; Fregni, Felipe


    There have been many changes in clinical trials methodology since the introduction of lithium and the beginning of the modern era of psychopharmacology in 1949. The nature and importance of these changes have not been fully addressed to date. As methodological flaws in trials can lead to false-negative or false-positive results, the objective of our study was to evaluate the impact of methodological changes in psychopharmacology clinical research over the past 60 years. We performed a systematic review from 1949 to 2009 on MEDLINE and Web of Science electronic databases, and a hand search of high impact journals on studies of seven major drugs (chlorpromazine, clozapine, risperidone, lithium, fluoxetine and lamotrigine). All controlled studies published 100 months after the first trial were included. Ninety-one studies met our inclusion criteria. We analyzed the major changes in abstract reporting, study design, participants' assessment and enrollment, methodology and statistical analysis. Our results showed that the methodology of psychiatric clinical trials changed substantially, with quality gains in abstract reporting, results reporting, and statistical methodology. Recent trials use more informed consent, periods of washout, intention-to-treat approach and parametric tests. Placebo use remains high and unchanged over time. Clinical trial quality of psychopharmacological studies has changed significantly in most of the aspects we analyzed. There was significant improvement in quality reporting and internal validity. These changes have increased study efficiency; however, there is room for improvement in some aspects such as rating scales, diagnostic criteria and better trial reporting. Therefore, despite the advancements observed, there are still several areas that can be improved in psychopharmacology clinical trials.

  13. The psychopharmacological activities of Vietnamese ginseng in mice: characterization of its psychomotor, sedative-hypnotic, antistress, anxiolytic, and cognitive effects. (United States)

    Dela Peña, Irene Joy I; Kim, Hee Jin; Botanas, Chrislean Jun; de la Peña, June Bryan; Van Le, Thi Hong; Nguyen, Minh Duc; Park, Jeong Hill; Cheong, Jae Hoon


    Panax vietnamensis Ha et Grushv. or Vietnamese ginseng (VG) is a recently discovered ginseng species. Studies on its chemical constituents have shown that VG is remarkably rich in ginseng saponins, particularly ocotillol saponins. However, the psychopharmacological effects of VG have not been characterized. Thus, in the present study we screened the psychopharmacological activities of VG in mice. VG extract (VGE) was orally administered to mice at various dosages to evaluate its psychomotor (open-field and rota-rod tests), sedative-hypnotic (pentobarbital-induced sleeping test), antistress (cold swimming test), anxiolytic (elevated plus-maze test), and cognitive (Y-maze and passive-avoidance tests) effects. VGE treatment increased the spontaneous locomotor activity, enhanced the endurance to stress, reduced the anxiety-like behavior, and ameliorated the scopolamine-induced memory impairments in mice. In addition, VGE treatment did not alter the motor balance and coordination of mice and did not potentiate pentobarbital-induced sleep, indicating that VGE has no sedative-hypnotic effects. The effects of VGE were comparable to those of the Korean Red Ginseng extract. VG, like other ginseng products, has significant and potentially useful psychopharmacological effects. This includes, but is not limited to, psychomotor stimulation, anxiolytic, antistress, and memory enhancing effects.

  14. Reassessing the cultural and psychopharmacological significance of Banisteriopsis caapi: preparation, classification and use among the Piaroa of Southern Venezuela. (United States)

    Rodd, Robin


    Recent attention to the monoamine oxidase inhibiting properties of Banisteriopsis caapi's harmala alkaloids has precluded a balanced assessment of B. caapi's overall significance to indigenous South American societies. Relatively little attention has been paid to the cultural contexts, local meanings and patterns of use of B. caapi among snuff-using societies, such as the Piaroa, who do not prepare decoctions containing N,N-dimethyltryptamine (DMT) admixtures. This article reviews the psychopharmacological literature on B. caapi in light of recent ethnographic work conducted among the Piaroa of southern Venezuela. Piaroa shamans use only B. caapi's cambium, identify at least five distinct varieties of B. caapi, and emphasise the plant's importance for heightening empathy. Some Piaroa people also attribute a range of extra-shamanic uses to B. caapi, including as a stimulant and hunting aid. In light of the psychopharmacological complexity of harmala alkaloids, and ethnographic evidence for a wide range of B. caapi uses,future research should reconsider B. caapi's cultural heritage and psychopharmacological potential as a stimulant and antidepressant-like substance.

  15. Mergers & Acquisitions

    DEFF Research Database (Denmark)

    Fomcenco, Alex

    MERGERS & ACQUISITIONS: Counseling and Choice of Method describes and analyzes the current state of law in Europe in regard to some relevant selected elements related to mergers and acquisitions, and the adviser’s counsel in this regard. The focus is aimed and maintained at application...

  16. Liquid chromatography, in combination with a quadrupole time-of-flight instrument (LC QTOF), with sequential window acquisition of all theoretical fragment-ion spectra (SWATH) acquisition: systematic studies on its use for screenings in clinical and forensic toxicology and comparison with information-dependent acquisition (IDA). (United States)

    Roemmelt, Andreas T; Steuer, Andrea E; Poetzsch, Michael; Kraemer, Thomas


    Forensic and clinical toxicological screening procedures are employing liquid chromatography-tandem mass spectrometry (LC-MS/MS) techniques with information-dependent acquisition (IDA) approaches more and more often. It is known that the complexity of a sample and the IDA settings might prevent important compounds from being triggered. Therefore, data-independent acquisition (DIA) methods should be more suitable for systematic toxicological analysis (STA). The DIA method sequential window acquisition of all theoretical fragment-ion spectra (SWATH), which uses Q1 windows of 20-35 Da for data-independent fragmentation, was systematically investigated for its suitability for STA. Quality of SWATH-generated mass spectra were evaluated with regard to mass error, relative abundance of the fragments, and library hits. With the Q1 window set to 20-25 Da, several precursors pass Q1 at the same time and are fragmented, thus impairing the library search algorithms to a different extent: forward fit was less affected than reverse fit and purity fit. Mass error was not affected. The relative abundance of the fragments was concentration dependent for some analytes and was influenced by cofragmentation, especially of deuterated analogues. Also, the detection rate of IDA compared to SWATH was investigated in a forced coelution experiment (up to 20 analytes coeluting). Even using several different IDA settings, it was observed that IDA failed to trigger relevant compounds. Screening results of 382 authentic forensic cases revealed that SWATH's detection rate was superior to IDA, which failed to trigger ∼10% of the analytes.

  17. Atypical Findings in Massive Bupropion Overdose: A Case Report and Discussion of Psychopharmacologic Issues. (United States)

    Zhu, Yuanjia; Kolawole, Tiwalola; Jimenez, Xavier F


    Bupropion is an atypical antidepressant that is structurally similar to amphetamines. Its primary toxic effects include seizure, sinus tachycardia, hypertension, and agitation; however, at higher amounts of ingestion, paradoxical cardiac effects are seen. We report the case of a 21-year-old woman who ingested 13.5 g of bupropion, a dose higher than any other previously reported. The patient presented with seizure, sinus tachycardia with prolonged QTc and QRS intervals, dilated pupils, and agitation. Four days after overdose, the patient's sinus tachycardia and prolonged QTc and QRS intervals resolved with symptomatic management, but she soon developed sinus bradycardia, hypotension, and mild transaminitis. With continued conservative management and close monitoring, her sinus bradycardia resolved 8 days after the overdose. The transaminitis resolved 12 days after the overdose. Our findings are consistent with previously reported toxic effects associated with common overdose amounts of bupropion. In addition, we have observed transient cardiotoxicity manifesting as sinus bradycardia associated with massive bupropion overdose. These findings are less frequently reported and must be considered when managing patients with massive bupropion overdose. We review the psychopharmacologic implications of this and comment on previous literature.

  18. Mental health issues among college students: who gets referred for psychopharmacology evaluation? (United States)

    Kirsch, Daniel J; Doerfler, Leonard A; Truong, Debbie


    To describe diagnostic and psychotropic medication prescription characteristics among college students referred by college counseling centers for psychopharmacologic evaluation. Participants were 540 college students referred by 6 college counseling centers in Massachusetts between November 2005 and May 2011. Students completed self-report measures of depression, anxiety, suicidal ideation and attempts, and substance use. Information regarding DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, 4th edition) diagnosis, previous history of medication prescription, and current psychotropic medication(s) prescribed by the consulting psychiatrist was obtained from medical records. Depression, anxiety, and attention-deficit/hyperactivity disorder (ADHD) were the most common psychiatric problems identified in students. Half of these students had been prescribed mediation prior to evaluation. Antidepressant medication was the most frequently prescribed medication. A large proportion of students reported previous thoughts of suicide, and 12% had made at least 1 suicide attempt. Depression, anxiety, and ADHD are common among students referred by college counseling centers for medication evaluation and treatment.

  19. The Psychopharmacology Algorithm Project at the Harvard South Shore Program: An Algorithm for Generalized Anxiety Disorder. (United States)

    Abejuela, Harmony Raylen; Osser, David N


    This revision of previous algorithms for the pharmacotherapy of generalized anxiety disorder was developed by the Psychopharmacology Algorithm Project at the Harvard South Shore Program. Algorithms from 1999 and 2010 and associated references were reevaluated. Newer studies and reviews published from 2008-14 were obtained from PubMed and analyzed with a focus on their potential to justify changes in the recommendations. Exceptions to the main algorithm for special patient populations, such as women of childbearing potential, pregnant women, the elderly, and those with common medical and psychiatric comorbidities, were considered. Selective serotonin reuptake inhibitors (SSRIs) are still the basic first-line medication. Early alternatives include duloxetine, buspirone, hydroxyzine, pregabalin, or bupropion, in that order. If response is inadequate, then the second recommendation is to try a different SSRI. Additional alternatives now include benzodiazepines, venlafaxine, kava, and agomelatine. If the response to the second SSRI is unsatisfactory, then the recommendation is to try a serotonin-norepinephrine reuptake inhibitor (SNRI). Other alternatives to SSRIs and SNRIs for treatment-resistant or treatment-intolerant patients include tricyclic antidepressants, second-generation antipsychotics, and valproate. This revision of the GAD algorithm responds to issues raised by new treatments under development (such as pregabalin) and organizes the evidence systematically for practical clinical application.

  20. State of the art psychopharmacological treatment options in seasonal affective disorder. (United States)

    Yildiz, Mesut; Batmaz, Sedat; Songur, Emrah; Oral, Esat Timuçin


    Seasonal affective disorder (SAD) is defined as a subtype of mood disorders in DSM 5, and it is characterized by a seasonal onset. SAD is proposed to be related to the seasonal changes in naturally occurring light, and the use of bright light therapy for depressive symptoms has been shown to reduce them in placebo controlled trials. Cognitive behavioral therapy has also been demonstrated to be effective in SAD. This review article aims to focus on the psychopharmacological treatment options for SAD. According to clinical trial results, first line treatment options seem to be sertraline and fluoxetine, and are well tolerated by the patients. There is some evidence that other antidepressants (e.g. bupropion) might be effective as well. Although clinical trials have shown that some of these antidepressants may be of benefit, a recent review has concluded that there is not enough evidence to support the use of any of these agents for the treatment of SAD yet. Moreover, more studies are still needed to evaluate the effectiveness of other treatment options, e.g., propranolol, melatonin, hypericum, etc. In addition to the above proposed treatments, patients with seasonal depressive symptoms should thoroughly be evaluated for any cues of bipolarity, and their treatment should be planned accordingly.

  1. Involvement of the endogenous opioid system in the psychopharmacological actions of ethanol: the role of acetaldehyde

    Directory of Open Access Journals (Sweden)

    Laura eFont


    Full Text Available Significant evidence implicates the endogenous opioid system (opioid peptides and receptors in the mechanisms underlying the psychopharmacological effects of ethanol. Ethanol modulates opioidergic signaling and function at different levels, including biosynthesis, release, and degradation of opioid peptides, as well as binding of endogenous ligands to opioid receptors. The role of β-endorphin and µ-opioid receptors (OR have been suggested to be of particular importance in mediating some of the behavioral effects of ethanol, including psychomotor stimulation and sensitization, consumption and conditioned place preference. Ethanol increases the release of β-endorphin from the hypothalamic arcuate nucleus (NArc, which can modulate activity of other neurotransmitter systems such as mesolimbic dopamine. The precise mechanism by which ethanol induces a release of β-endorphin, thereby inducing behavioral responses, remains to be elucidated. The present review summarizes accumulative data suggesting that the first metabolite of ethanol, the psychoactive compound acetaldehyde, could participate in such mechanism. Two lines of research involving acetaldehyde are reviewed: 1 implications of the formation of acetaldehyde in brain areas such as the NArc, with high expression of ethanol metabolizing enzymes and presence of cell bodies of endorphinic neurons and 2 the formation of condensation products between DA and acetaldehyde such as salsolinol, which exerts its actions via OR.


    National Research Council Canada - National Science Library

    Rodgers Mavhiki


      Mergers and acquisitions (M&A) tend to be dominated by M&A specialists such as lawyers, valuations specialists and investment gurus, leaving the funding function for the Chief Financial Officer (CFO...

  3. 78 FR 34020 - Federal Acquisition Regulation; Uniform Procurement Identification (United States)


    .... Recommendation number 3 of this report is to implement a uniform award identification system among various... 9000-AM60 Federal Acquisition Regulation; Uniform Procurement Identification AGENCY: Department of... Acquisition Regulation (FAR) to implement a uniform Procurement Instrument Identification (PIID) numbering...

  4. The Acquisition Experiences of Kazoil

    DEFF Research Database (Denmark)

    Minbaeva, Dana; Muratbekova-Touron, Maral


    This case describes two diverging post-acquisition experiences of KazOil, an oil drilling company in Kazakhstan, in the years after the dissolution of the Soviet Union. When the company was bought by the Canadian corporation Hydrocarbons Ltd in 1996, exposed to new human resource strategies...... among students that cultural distance is not the main determinant for the success of social integration mechanisms in post-acquisition situations. On the contrary, the relationship between integration instrument and integration success is also governed by contextual factors such as the attractiveness...... of the acquisition target or state of development of HRM in the target country....

  5. Measurement, instrumentation, and sensors handbook

    CERN Document Server

    Eren, Halit


    The Second Edition of the bestselling Measurement, Instrumentation, and Sensors Handbook brings together all aspects of the design and implementation of measurement, instrumentation, and sensors. Reflecting the current state of the art, it describes the use of instruments and techniques for performing practical measurements in engineering, physics, chemistry, and the life sciences and discusses processing systems, automatic data acquisition, reduction and analysis, operation characteristics, accuracy, errors, calibrations, and the incorporation of standards for control purposes. Organized acco

  6. Psychopharmacologic treatment and blood transfusion in fast-track total hip and knee arthroplasty. (United States)

    Gylvin, Silas Hinsch; Jørgensen, Christoffer Calov; Fink-Jensen, Anders; Johansson, Pär I; Kehlet, Henrik


    Selective serotonin reuptake inhibitors (SSRIs) and other psychotropics are receiving increasing attention due to reports on inhibition of thrombocyte function and an increased bleeding risk in surgical settings. Studies in total hip and total knee arthroplasty (THA and TKA, respectively) have shown conflicting results, questioning whether the potential increased bleeding risk is of clinical importance. Prospective consecutive collection of data on preoperative comorbidity in patients undergoing primary unilateral THA or TKA was cross-referenced with regional transfusion databases and The Danish National Database of Reimbursed Prescriptions for information regarding blood transfusions and psychopharmacologic treatment. All participating orthopedic centers followed similar perioperative guidelines. Multiple logistic regression analysis was applied to calculate odds ratios (ORs) for transfusion between preoperative users and nonusers of psychotropics. Of 8402 patients, 569 (6.8%) were SSRI users versus 7833 (93.2%) nonusers. A total of 109 (19,2%) patients in the SSRI group and 700 (8.9%) in the "no-SSRI" group received blood intra- or postoperatively. Preoperative SSRI treatment was a risk factor for perioperative transfusion (OR, 1.98; 95% confidence interval [CI], 1.44-2.70). Other antidepressants (OAs) were associated with an increased risk of transfusion (OR, 1.69; 95% CI, 1.17-2.44) as well as the combination of SSRIs and OAs (OR, 3.31; 95% CI, 1.79-6.13). Singular use of antipsychotics (APs) increased the transfusion risk (OR, 2.37; 95% CI, 1.04-2.41), while AP medicine in combination with antidepressants did not. Preoperative treatment with SSRIs, OAs, or APs are independent risk factors for blood transfusion in elective fast-track THA and TKA. © 2017 AABB.

  7. Unveiling the role of melatonin MT2 receptors in sleep, anxiety and other neuropsychiatric diseases: a novel target in psychopharmacology. (United States)

    Comai, Stefano; Gobbi, Gabriella


    Melatonin (MLT) is a pleiotropic neurohormone controlling many physiological processes and whose dysfunction may contribute to several different diseases, such as neurodegenerative diseases, circadian and mood disorders, insomnia, type 2 diabetes and pain. Melatonin is synthesized by the pineal gland during the night and acts through 2 G-protein coupled receptors (GPCRs), MT1 (MEL1a) and MT2 (MEL1b). Although a bulk of research has examined the physiopathological effects of MLT, few studies have investigated the selective role played by MT1 and MT2 receptors. Here we have reviewed current knowledge about the implications of MT2 receptors in brain functions. We searched PubMed, Web of Science, Scopus, Google Scholar and articles' reference lists for studies on MT2 receptor ligands in sleep, anxiety, neuropsychiatric diseases and psychopharmacology, including genetic studies on the MTNR1B gene, which encodes the melatonin MT2 receptor. These studies demonstrate that MT2 receptors are involved in the pathophysiology and pharmacology of sleep disorders, anxiety, depression, Alzheimer disease and pain and that selective MT2 receptor agonists show hypnotic and anxiolytic properties. Studies examining the role of MT2 receptors in psychopharmacology are still limited. The development of novel selective MT2 receptor ligands, together with further preclinical in vivo studies, may clarify the role of this receptor in brain function and psychopharmacology. The superfamily of GPCRs has proven to be among the most successful drug targets and, consequently, MT2 receptors have great potential for pioneer drug discovery in the treatment of mental diseases for which limited therapeutic targets are currently available.

  8. Electro-Optical Data Acquisition and Tracking System (United States)

    Federal Laboratory Consortium — The Electro-Optical Data Acquisition and Tracking System (EDATS) dynamically tracks and measures target signatures. It consists of an instrumentation van integrated...

  9. Mergers + acquisitions. (United States)

    Hoppszallern, Suzanna


    The hospital sector in 2001 led the health care field in mergers and acquisitions. Most deals involved a network augmenting its presence within a specific region or in a market adjacent to its primary service area. Analysts expect M&A activity to increase in 2002.

  10. Mergers & Acquisitions

    DEFF Research Database (Denmark)

    Fomcenco, Alex

    This dissertation is a legal dogmatic thesis, the goal of which is to describe and analyze the current state of law in Europe in regard to some relevant selected elements related to mergers and acquisitions, and the adviser’s counsel in this regard. Having regard to the topic of the dissertation...

  11. The SINQ data acquisition environment

    Energy Technology Data Exchange (ETDEWEB)

    Maden, D. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)


    The data acquisition environment for the neutron scattering instruments supported by LNS at SINQ is described. The intention is to provide future users with the necessary background to the computing facilities on site rather than to present a user manual for the on-line system. (author) 5 figs., 6 refs.

  12. Radioisotope instruments

    CERN Document Server

    Cameron, J F; Silverleaf, D J


    International Series of Monographs in Nuclear Energy, Volume 107: Radioisotope Instruments, Part 1 focuses on the design and applications of instruments based on the radiation released by radioactive substances. The book first offers information on the physical basis of radioisotope instruments; technical and economic advantages of radioisotope instruments; and radiation hazard. The manuscript then discusses commercial radioisotope instruments, including radiation sources and detectors, computing and control units, and measuring heads. The text describes the applications of radioisotop

  13. [Review of psychopharmacological treatments in adolescents and adults with autistic disorders]. (United States)

    Baghdadli, A; Gonnier, V; Aussilloux, C


    Autism is an early developmental disorder. It leads to severe and durable disturbances. Given this problem, no treatment can be excluded a priori. Thus, many approaches are used to deal with autistic disorders. In France, pharmacological treatments are, for instance, largely and mostly used in adults. In the USA, these treatments concern 50% of persons with autism of any age. Nevertheless, they are rarely based on controlled studies. At the present, however, prescriptions and expected effects appear to be hard to localize. Furthermore, only few controlled studies validate their use. Aim - We offer a review of studies about medical treatments used in adolescents and adults with autism. They are classified in 3 categories: the first (category I) includes drugs used for their neurochemical effects focusing on autistic signs. The second (category II) covers drugs used for treatment of behavioural disorders frequently associated with autism. The third (category III) corresponds to a wide range of drugs or vitamins for wich only few case studies exist reporting irregular positive effects. The main hypothesis of this review is that autism involves a dysfunction of the neuromediation systems. This hypothesis opens new perspectives in the research of medical treatments in autism by focusing on molecules, which are supposed to have an effect on neuromediation systems. Method - Our review is based on studies, which have been published during the past twenty years. For many studies, data are limited to adolescents and adults. So we expanded our review to data available in children. The data bases that we have used are medline and psyclit. Keywords have been chosen according to: pharmacological considerations (psychotropic, psychoactive drugs, psychopharmacology) and clinical symptoms (autism, automutilations, aggressive behavior, and hyperactivity). Hypothesis of a dysfunction in the neuromediation systems in autism - Many studies exist about biochemical abnormalities in

  14. Instrumentation Methodology for Automobile Crash Testing (United States)


    Principal characteristics of existing data acquisition practices and instrumentation methodologies have been reviewed to identify differences which are responsible for difficulties in comparing and interpreting structural crash test data. Recommendat...

  15. Cannabinoid mitigation of neuronal morphological change important to development and learning: insight from a zebra finch model of psychopharmacology. (United States)

    Soderstrom, Ken; Gilbert, Marcoita T


    Normal CNS development proceeds through late-postnatal stages of adolescent development. The activity-dependence of this development underscores the significance of CNS-active drug exposure prior to completion of brain maturation. Exogenous modulation of signaling important in regulating normal development is of particular concern. This mini-review presents a summary of the accumulated behavioral, physiological and biochemical evidence supporting such a key regulatory role for endocannabinoid signaling during late-postnatal CNS development. Our focus is on the data obtained using a unique zebra finch model of developmental psychopharmacology. This animal has allowed investigation of neuronal morphological effects essential to establishment and maintenance of neural circuitry, including processes related to synaptogenesis and dendritic spine dynamics. Altered neurophysiology that follows exogenous cannabinoid exposure during adolescent development has the potential to persistently alter cognition, learning and memory. Copyright © 2012 Elsevier Inc. All rights reserved.

  16. Bipolar disorder ignored by the Mental Health National Service framework but not forgotten by the British Association for Psychopharmacology. (United States)

    McAllister-Williams, R H; Watson, S


    Bipolar disorder (BD) is a severe mental illness that has been largely ignored by the National Service Framework (NSF) for Mental Health. This is particularly notable because it is associated with a higher suicide rate than schizophrenia and has a greater burden of disability. The NSF offers little guidance on service models that specifically consider BD. This is of concern because of the complexities that are inherent in the management of BD. These deficiencies in the NSF may have far-reaching implications for resource allocation, service organization, and patient management and well-being. Moreover, the standards and performance targets laid out in the NSF will be difficult to meet if this important and common mental illness is not specifically catered for in mental health services. Local Implementation Teams would be well advised to take note of the recently published British Association for Psychopharmacology guidelines for the management of BD.

  17. Lights! Camera! Action Projects! Engaging Psychopharmacology Students in Service-based Action Projects Focusing on Student Alcohol Abuse. (United States)

    Kennedy, Susan


    Alcohol abuse continues to be an issue of major concern for the health and well-being of college students. Estimates are that over 80% of college students are involved in the campus "alcohol culture." Annually, close to 2000 students die in the United States due to alcohol-related accidents, with another 600,000 sustaining injury due to alcohol-related incidents (NIAAA, 2013). Students enrolled in a Psychopharmacology course engaged in action projects (community outreach) focused on alcohol abuse on our campus. Research has indicated that these types of projects can increase student engagement in course material and foster important skills, including working with peers and developing involvement in one's community. This paper describes the structure and requirements of five student outreach projects and the final projects designed by the students, summarizes the grading and assessment of the projects, and discusses the rewards and challenges of incorporating such projects into a course.

  18. Psychiatric Disorders and Psychopharmacologic Treatment as Risk Factors in Elective Fast-track Total Hip and Knee Arthroplasty

    DEFF Research Database (Denmark)

    Jørgensen, Christoffer C; Knop, Joachim; Nordentoft, Merete


    (2.24; 1.51 to 3.32 and 1.82; 1.27 to 2.61), and antipsychotics (1.85; 1.03 to 3.31, 30 days only). In PsD patients, pain (1.4%), postoperative anemia (1.1%), and pulmonary complications (1.1%) were the most frequent causes of LOS more than 4 days. Hip displacements (2.8%) and falls (1.9%) were...... the most frequent readmissions, and 90-day surgery-related mortality was 0.7% with and 0.2% without PsD. CONCLUSIONS: Psychopharmacologically treated PsD is a risk factor for postoperative morbidity after fast-track arthroplasty, regardless of treatment type. This may be due to PsD per se and/or drug...

  19. Evidence-based pharmacological treatment of anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder : A revision of the 2005 guidelines from the British Association for Psychopharmacology

    NARCIS (Netherlands)

    Baldwin, David S.; Anderson, Ian M.; Nutt, David J.; Allgulander, Christer; Bandelow, Borwin; den Boer, Johan A.; Christmas, David M.; Davies, Simon; Fineberg, Naomi; Lidbetter, Nicky; Malizia, Andrea; McCrone, Paul; Nabarro, Daniel; O'Neill, Catherine; Scott, Jan; van der Wee, Nic; Wittchen, Hans-Ulrich

    This revision of the 2005 British Association for Psychopharmacology guidelines for the evidence-based pharmacological treatment of anxiety disorders provides an update on key steps in diagnosis and clinical management, including recognition, acute treatment, longer-term treatment, combination

  20. Arduino based data acquisition system


    Veramendi Fernández, Megara


    This project explains the design and functioning of an Arduino based data acquisition system. By using Arduino UNO and LabVIEW software, it has been possible to measure different parameters such as temperature, illuminance, movement or even the presence of magnetic fields. Controlling the microcontroller on a very easy way from a computer has been possible thanks to the interface offered by National Instruments software. Wireless communication with the microcontroller has also been introduced...

  1. [Portable instrument for arteriosclerosis assessment]. (United States)

    Cao, Shuai; Chen, Xiang


    A portable instrument for arteriosclerosis assessment containing sensor module, acquisition board and embedded module was developed for home care in this paper. The sensor module consists of one ECG module and three pulse wave extraction modules, synchronously acquiring human ECG and pulse wave signal of carotid, radial, and dorsal, respectively. The acquisition board converts the sensor module's analog output signals into digital signals and transmits them to the embedded module. The embedded module realizes the functions including signal display, storage and the calculation and output of pulse wave velocity. The structure of the proposed portable instrument is simple, easy to use, and easy to expand. Small size, low cost, and low power consumption are also the advantages of this device. Experimental results demonstrated that the proposed portable instrument for arteriosclerosis assessment has high accuracy, good repeatability and can assess the degree of atherosclerosis appropriately.

  2. Technical presentation - KEITHLEY Instruments - CANCELLED

    CERN Multimedia

    FI Department


    10 March 2009 13:30 – 15:30, Council Chamber, Bldg. 503 Keithley markets highly accurate instruments and data acquisition products, as well as complete system solutions for high-volume production and assembly testing. Keithley Instruments, Inc. designs, develops, manufactures and markets complex electronic instruments and systems geared to the specialized needs of electronics manufacturers for high-performance production testing, process monitoring, product development and research. Products and Services: Digital Multimeters and Data Acquisition Systems Current / Voltage Source and Measure Products Low Current / High Resistance Measurement Products Function/Pulse/Arbitrary/Pattern Generators Low Voltage/Low Resistance Measurement Products RF Spectrum Analyzer / RF Signal Generator / RF Switching Semiconductor Device Characterization Program: Topic 1: Welcome and short overview of new Products SMU 26XXA / ARB Generator 3390 / DMM 3706 / E-Meter 6517B Topic 2a: Te...

  3. 2017 NAIP Acquisition Map (United States)

    Farm Service Agency, Department of Agriculture — Planned States for 2017 NAIP acquisition and acquisition status layer (updated daily). Updates to the acquisition seasons may be made during the season to...

  4. Psychopharmacological treatment of psychotic mania and psychotic bipolar depression compared to non-psychotic mania and non-psychotic bipolar depression. (United States)

    Bjørklund, Louise B; Horsdal, Henriette T; Mors, Ole; Gasse, Christiane; Østergaard, Søren D


    An evidence base for the treatment of mania and bipolar depression with psychotic symptoms is lacking. Nevertheless, clinicians may have a preference for treating episodes of bipolar disorder with or without psychotic symptoms in different ways, which is likely to reflect notions of differential efficacy of treatments between these subtypes. This study aimed to investigate whether the psychopharmacological treatment of psychotic and non-psychotic episodes of mania and bipolar depression, respectively, differs in clinical practice. We conducted a register-based study assessing the psychopharmacological treatment of all individuals receiving their first diagnosis of mania or bipolar depression between 2010 and 2012. The psychopharmacological treatment within 3 months following the time of diagnosis was considered. Potential differences in psychopharmacological treatment between the psychotic and non-psychotic subtypes of mania and bipolar depression, respectively, were investigated by means of Pearson's χ(2) test and logistic regression adjusted for sex and age at diagnosis of bipolar disorder. A total of 827 patients were included in the analyses. The adjusted odds ratio (aOR) for treatment with an antipsychotic was 1.71 (95% confidence interval [CI]: 1.18-2.48, Pbipolar depression. The aOR for treatment with the combination of an antipsychotic and an anticonvulsant was 1.60 (95% CI: 1.06-2.43, Pbipolar psychotic depression. It would be of interest to conduct studies evaluating whether antipsychotics represent the superior pharmacological treatment for psychotic mania and psychotic bipolar depression. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. Luminescence Instrumentation

    DEFF Research Database (Denmark)

    Jain, Mayank; Bøtter-Jensen, Lars


    This chapter gives an introduction to instrumentation for stimulated luminescence studies, with special focus on luminescence dating using the natural dosimeters, quartz and feldspars. The chapter covers basic concepts in luminescence detection, and thermal and optical stimulation, and reference...... irradiation. It then briefly describes development of spectrometers in dating applications, and finally gives an overview of recent development in the field directly linked to novel instrumentation. Contents of Paper...

  6. WRATS Integrated Data Acquisition System (United States)

    Piatak, David J.


    The Wing and Rotor Aeroelastic Test System (WRATS) data acquisition system (DAS) is a 64-channel data acquisition display and analysis system specifically designed for use with the WRATS 1/5-scale V-22 tiltrotor model of the Bell Osprey. It is the primary data acquisition system for experimental aeroelastic testing of the WRATS model for the purpose of characterizing the aeromechanical and aeroelastic stability of prototype tiltrotor configurations. The WRATS DAS was also used during aeroelastic testing of Bell Helicopter Textron s Quad-Tiltrotor (QTR) design concept, a test which received international attention. The LabVIEW-based design is portable and capable of powering and conditioning over 64 channels of dynamic data at sampling rates up to 1,000 Hz. The system includes a 60-second circular data archive, an integrated model swashplate excitation system, a moving block damping application for calculation of whirl flutter mode subcritical damping, a loads and safety monitor, a pilot-control console display, data analysis capabilities, and instrumentation calibration functions. Three networked computers running custom-designed LabVIEW software acquire data through National Instruments data acquisition hardware. The aeroelastic model (see figure) was tested with the DAS at two facilities at NASA Langley, the Transonic Dynamics Tunnel (TDT) and the Rotorcraft Hover Test Facility (RHTF). Because of the need for seamless transition between testing at these facilities, DAS is portable. The software is capable of harmonic analysis of periodic time history data, Fast Fourier Transform calculations, power spectral density calculations, and on-line calibration of test instrumentation. DAS has a circular buffer archive to ensure critical data is not lost in event of model failure/incident, as well as a sample-and-hold capability for phase-correct time history data.

  7. Pointers, Lessons Learned, and Rules of Thumb for Successful Vibro-Acoustic Data Acquisition (United States)

    Rossoni, Peter


    This presentation contains helpful pointers for successful vibroacoustic data acquisition in the following three areas: Instrumentation, Vibration Control and Pyro-shock data acquisition and analysis. A helpful bibliography is provided.

  8. Instrumental Capital

    Directory of Open Access Journals (Sweden)

    Gabriel Valerio


    Full Text Available During the history of human kind, since our first ancestors, tools have represented a mean to reach objectives which might otherwise seemed impossibles. In the called New Economy, where tangibles assets appear to be losing the role as the core element to produce value versus knowledge, tools have kept aside man in his dairy work. In this article, the author's objective is to describe, in a simple manner, the importance of managing the organization's group of tools or instruments (Instrumental Capital. The characteristic conditions of this New Economy, the way Knowledge Management deals with these new conditions and the sub-processes that provide support to the management of Instrumental Capital are described.

  9. Development and implantation of a control and data acquisition program for the calibration of instruments for diagnostic radiology; Desenvolvimento e implantacao de um programa de controle e aquisicao de dados na calibracao de instrumentos em radiodiagnostico

    Energy Technology Data Exchange (ETDEWEB)

    Betti, Flavio


    Design techniques of an automatic control system implementing corrected kerma determination and shutter command in the calibration laboratory at IPEN are shown, as well as the periodic calibration program developed for a monitor chamber for several X-ray beam qualities used for diagnostic radiology and radiation protection instruments. Two reference electrometers, a multichannel secondary standard thermometer, and an absolute pressure barometer were connected to the Rs-232 interface from a PC computer equipped with a National Instruments multi function analog and digital I/O card. LabVIEW{sup MR} was chosen as programming tool, which allowed for the development of a suite of programs for both controlling the shutter timing cycles and the calibration of the monitor chamber against a reference standard. A detailed description of the methods used for troubleshooting, fine tuning of parameters and evaluation of program results is followed by an analysis showing that considerable advantages regarding reduction of time and precision improvements during the calibrations could be achieved by the use of the developed programs, particularly under adverse conditions like those found during short expositions, or instead during long irradiation intervals where fluctuation of parameters like kerma rate or room conditions (temperature or pressure) can be found. (author)

  10. Evidence-based guidelines for treating bipolar disorder: revised third edition Recommendations from the British Association for Psychopharmacology (United States)

    Goodwin, G.M.; Haddad, P. M.; Ferrier, I.N.; Aronson, J.K.; Barnes, T.R.H.; Cipriani, A.; Coghill, D.R.; Fazel, S.; Geddes, J.R.; Grunze, H.; Holmes, E.A.; Howes, O.; Hudson, S.; Hunt, N.; Jones, I.; Macmillan, I.C.; McAllister-Williams, H.; Miklowitz, D.M.; Morriss, R.; Munafò, M.; Paton, C.; Saharkian, B.J.; Saunders, K.E.A.; Sinclair, J.M.A.; Taylor, D.; Vieta, E.; Young, A.H.


    The British Association for Psychopharmacology guidelines specify the scope and targets of treatment for bipolar disorder. The third version is based explicitly on the available evidence and presented, like previous Clinical Practice Guidelines, as recommendations to aid clinical decision making for practitioners: it may also serve as a source of information for patients and carers, and assist audit. The recommendations are presented together with a more detailed review of the corresponding evidence. A consensus meeting, involving experts in bipolar disorder and its treatment, reviewed key areas and considered the strength of evidence and clinical implications. The guidelines were drawn up after extensive feedback from these participants. The best evidence from randomized controlled trials and, where available, observational studies employing quasi-experimental designs was used to evaluate treatment options. The strength of recommendations has been described using the GRADE approach. The guidelines cover the diagnosis of bipolar disorder, clinical management, and strategies for the use of medicines: in short-term treatment of episodes, relapse prevention and stopping treatment. The use of medication is integrated with a coherent approach to psychoeducation and behaviour change. PMID:26979387

  11. Instrumental aspects (United States)

    Qureshi, Navid


    Every neutron scattering experiment requires the choice of a suited neutron diffractometer (or spectrometer in the case of inelastic scattering) with its optimal configuration in order to accomplish the experimental tasks in the most successful way. Most generally, the compromise between the incident neutron flux and the instrumental resolution has to be considered, which is depending on a number of optical devices which are positioned in the neutron beam path. In this chapter the basic instrumental principles of neutron diffraction will be explained. Examples of different types of experiments and their respective expectable results will be shown. Furthermore, the production and use of polarized neutrons will be stressed.

  12. RHIC instrumentation (United States)

    Shea, T. J.; Witkover, R. L.


    The Relativistic Heavy Ion Collider (RHIC) consists of two 3.8 km circumference rings utilizing 396 superconducting dipoles and 492 superconducting quadrupoles. Each ring will accelerate approximately 60 bunches of 1011 protons to 250 GeV, or 109 fully stripped gold ions to 100 GeV/nucleon. Commissioning is scheduled for early 1999 with detectors for some of the 6 intersection regions scheduled for initial operation later in the year. The injection line instrumentation includes: 52 beam position monitor (BPM) channels, 56 beam loss monitor (BLM) channels, 5 fast integrating current transformers and 12 video beam profile monitors. The collider ring instrumentation includes: 667 BPM channels, 400 BLM channels, wall current monitors, DC current transformers, ionization profile monitors (IPMs), transverse feedback systems, and resonant Schottky monitors. The use of superconducting magnets affected the beam instrumentation design. The BPM electrodes must function in a cryogenic environment and the BLM system must prevent magnet quenches from either fast or slow losses with widely different rates. RHIC is the first superconducting accelerator to cross transition, requiring close monitoring of beam parameters at this time. High space-charge due to the fully stripped gold ions required the IPM to collect magnetically guided electrons rather than the conventional ions. Since polarized beams will also be accelerated in RHIC, additional constraints were put on the instrumentation. The orbit must be well controlled to minimize depolarizing resonance strengths. Also, the position monitors must accommodate large orbit displacements within the Siberian snakes and spin rotators. The design of the instrumentation will be presented along with results obtained during bench tests, the injection line commissioning, and the first sextant test.

  13. GRAVITY acquisition camera: characterization results (United States)

    Anugu, Narsireddy; Garcia, Paulo; Amorim, Antonio; Wiezorrek, Erich; Wieprecht, Ekkehard; Eisenhauer, Frank; Ott, Thomas; Pfuhl, Oliver; Gordo, Paulo; Perrin, Guy; Brandner, Wolfgang; Straubmeier, Christian; Perraut, Karine


    GRAVITY acquisition camera implements four optical functions to track multiple beams of Very Large Telescope Interferometer (VLTI): a) pupil tracker: a 2×2 lenslet images four pupil reference lasers mounted on the spiders of telescope secondary mirror; b) field tracker: images science object; c) pupil imager: reimages telescope pupil; d) aberration tracker: images a Shack-Hartmann. The estimation of beam stabilization parameters from the acquisition camera detector image is carried out, for every 0.7 s, with a dedicated data reduction software. The measured parameters are used in: a) alignment of GRAVITY with the VLTI; b) active pupil and field stabilization; c) defocus correction and engineering purposes. The instrument is now successfully operational on-sky in closed loop. The relevant data reduction and on-sky characterization results are reported.

  14. Speed in Acquisitions

    DEFF Research Database (Denmark)

    Meglio, Olimpia; King, David R.; Risberg, Annette


    The advantage of speed is often invoked by academics and practitioners as an essential condition during post-acquisition integration, frequently without consideration of the impact earlier decisions have on acquisition speed. In this article, we examine the role speed plays in acquisitions across...... the acquisition process using research organized around characteristics that display complexity with respect to acquisition speed. We incorporate existing research with a process perspective of acquisitions in order to present trade-offs, and consider the influence of both stakeholders and the pre......-deal-completion context on acquisition speed, as well as the organization’s capabilities to facilitating that speed. Observed trade-offs suggest both that acquisition speed often requires longer planning time before an acquisition and that associated decisions require managerial judgement. A framework for improving...

  15. Broadband Wireless Data Acquisition and Control Device Project (United States)

    National Aeronautics and Space Administration — Mobitrum is proposing to develop a broadband wireless device for real-time data acquisition and monitoring applicable to the field instrumentation and control...

  16. Language Acquisition without an Acquisition Device (United States)

    O'Grady, William


    Most explanatory work on first and second language learning assumes the primacy of the acquisition phenomenon itself, and a good deal of work has been devoted to the search for an "acquisition device" that is specific to humans, and perhaps even to language. I will consider the possibility that this strategy is misguided and that language…

  17. Laser instrument

    Energy Technology Data Exchange (ETDEWEB)

    Cabrera, R.J.; Eagar, T.W.


    An instrument is described for intercepting a carbon dioxide incident laser beam after it has energized a desired surgical target site but before it energizes material adjacent to the surgical target site. The instrument consists of: a substrate means for transmitting energy received from a laser beam away from a surgical target site, the substrate means having a high thermal conductivity and an exterior surface; a coating means for absorbing laser energy at the wavelength of a carbon dioxide laser, the coating means covering substantially the entirety of the exterior surface of the substrate means and having a high absorptivity for energy at the wavelength of the incident laser beam; and, the coating means having thickness which is large enough to provide high absorptivity but small enough to permit absorbed energy to be readily transferred to the high conductivity substrate means, and the thickness of the coating means being not greater than 0.001 inch.

  18. Instrumentation viewpoint


    Sarti, Centro Tecnológico de Vilanova i la Geltrú


    Following our traditional edition line, on this issue our magazine presents the annual summary of the different projects and research activities developed by SARTI research group during 2011. The research projects undertaken by SARTI, in collaboration with other Spanish and international research teams, are linked to the development of instrumentation technology for marine applications, as well as for general industry. SARTI, as research group of the Universitat Politècnica de Cat...

  19. Modelling live forensic acquisition

    CSIR Research Space (South Africa)

    Grobler, MM


    Full Text Available This paper discusses the development of a South African model for Live Forensic Acquisition - Liforac. The Liforac model is a comprehensive model that presents a range of aspects related to Live Forensic Acquisition. The model provides forensic...

  20. Managing acquisitions and mergers. (United States)

    Shorr, A S


    Acquisitions and mergers must be well managed if they are to capture market share and achieve profitability. Acquisition strategies must reflect sensitivity to legal, financial and community factors and to the internal strengths, needs and weaknesses of both organizations.

  1. Playing at Serial Acquisitions

    NARCIS (Netherlands)

    J.T.J. Smit (Han); T. Moraitis (Thras)


    textabstractBehavioral biases can result in suboptimal acquisition decisions-with the potential for errors exacerbated in consolidating industries, where consolidators design serial acquisition strategies and fight escalating takeover battles for platform companies that may determine their future

  2. Calo trigger acquisition system

    CERN Multimedia

    Franchini, Matteo


    Calo trigger acquisition system - Evolution of the acquisition system from a multiple boards system (upper, orange cables) to a single board one (below, light blue cables) where all the channels are collected in a single board.

  3. CCNP Award Paper: Unveiling the role of melatonin MT2 receptors in sleep, anxiety and other neuropsychiatric diseases: a novel target in psychopharmacology (United States)

    Comai, Stefano; Gobbi, Gabriella


    Background Melatonin (MLT) is a pleiotropic neurohormone controlling many physiological processes and whose dysfunction may contribute to several different diseases, such as neurodegenerative diseases, circadian and mood disorders, insomnia, type 2 diabetes and pain. Melatonin is synthesized by the pineal gland during the night and acts through 2 G-protein coupled receptors (GPCRs), MT1 (MEL1a) and MT2 (MEL1b). Although a bulk of research has examined the physiopathological effects of MLT, few studies have investigated the selective role played by MT1 and MT2 receptors. Here we have reviewed current knowledge about the implications of MT2 receptors in brain functions. Methods We searched PubMed, Web of Science, Scopus, Google Scholar and articles reference lists for studies on MT2 receptor ligands in sleep, anxiety, neuropsychiatric diseases and psychopharmacology, including genetic studies on the MTNR1B gene, which encodes the melatonin MT2 receptor. Results These studies demonstrate that MT2 receptors are involved in the pathophysiology and pharmacology of sleep disorders, anxiety, depression, Alzheimer disease and pain and that selective MT2 receptor agonists show hypnotic and anxiolytic properties. Limitations Studies examining the role of MT2 receptors in psychopharmacology are still limited. Conclusion The development of novel selective MT2 receptor ligands, together with further preclinical in vivo studies, may clarify the role of this receptor in brain function and psychopharmacology. The superfamily of GPCRs has proven to be among the most successful drug targets and, consequently, MT2 receptors have great potential for pioneer drug discovery in the treatment of mental diseases for which limited therapeutic targets are currently available. PMID:23971978

  4. InstrumentationPod (IPOD) User Guide

    Energy Technology Data Exchange (ETDEWEB)

    Parker, Robert F. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)


    This document describes the Instrumentation Pod (IPOD) and its operation and use. The IPOD is a low-power detector system comprising a 3He tube with preamp for neutron detection, a microcontroller-based data acquisition system, a GPS receiver for locationdetermination and time-synchronization, and power filtering and protection. The IPOD is intended to be bolted to the top of Dual-Use Casks stored at Baikal-1 in Kazakhstan in order to maintain continuity of knowledge of the materials stored within the cask. The data acquisition system receives pulses from the neutron-detection preamp, combines this information with other sensor data, and stores the result on two SD cards that are part of the data acquisition system. Firmware in the data acquisition system controls collection and storing of the data and enables configuration of the acquisition parameters.

  5. Acquisition: Acquisition of the Evolved SEASPARROW Missile

    National Research Council Canada - National Science Library


    .... The Evolved SEASPARROW Missile, a Navy Acquisition Category II program, is an improved version of the RIM-7P SEASPARROW missile that will intercept high-speed maneuvering, anti-ship cruise missiles...

  6. Confidence-Based Feature Acquisition (United States)

    Wagstaff, Kiri L.; desJardins, Marie; MacGlashan, James


    Confidence-based Feature Acquisition (CFA) is a novel, supervised learning method for acquiring missing feature values when there is missing data at both training (learning) and test (deployment) time. To train a machine learning classifier, data is encoded with a series of input features describing each item. In some applications, the training data may have missing values for some of the features, which can be acquired at a given cost. A relevant JPL example is that of the Mars rover exploration in which the features are obtained from a variety of different instruments, with different power consumption and integration time costs. The challenge is to decide which features will lead to increased classification performance and are therefore worth acquiring (paying the cost). To solve this problem, CFA, which is made up of two algorithms (CFA-train and CFA-predict), has been designed to greedily minimize total acquisition cost (during training and testing) while aiming for a specific accuracy level (specified as a confidence threshold). With this method, it is assumed that there is a nonempty subset of features that are free; that is, every instance in the data set includes these features initially for zero cost. It is also assumed that the feature acquisition (FA) cost associated with each feature is known in advance, and that the FA cost for a given feature is the same for all instances. Finally, CFA requires that the base-level classifiers produce not only a classification, but also a confidence (or posterior probability).

  7. The “Endless Trip” among the NPS Users: Psychopathology and Psychopharmacology in the Hallucinogen-Persisting Perception Disorder. A Systematic Review

    Directory of Open Access Journals (Sweden)

    Laura Orsolini


    Full Text Available Hallucinogen-persisting perception disorder (HPPD is a syndrome characterized by prolonged or reoccurring perceptual symptoms, reminiscent of acute hallucinogen effects. HPPD was associated with a broader range of LSD (lysergic acid diethylamide-like substances, cannabis, methylenedioxymethamphetamine (MDMA, psilocybin, mescaline, and psychostimulants. The recent emergence of novel psychoactive substances (NPS posed a critical concern regarding the new onset of psychiatric symptoms/syndromes, including cases of HPPD. Symptomatology mainly comprises visual disorders (i.e., geometric pseudo-hallucinations, haloes, flashes of colors/lights, motion-perception deficits, afterimages, micropsia, more acute awareness of floaters, etc., even though depressive symptoms and thought disorders may be comorbidly present. Although HPPD was first described in 1954, it was just established as a fully syndrome in 2000, with the revised fourth version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR. HPPD neural substrates, risk factors, and aetiopathogenesys still largely remain unknown and under investigation, and many questions about its pharmacological targets remain unanswered too. A critical mini review on psychopathological bases, etiological hypothesis, and psychopharmacological approaches toward HPPD, including the association with some novel substances, are provided here, by means of a literature search on PubMed/Medline, Google Scholar, and Scopus databases without time restrictions, by using a specific set of keywords. Pharmacological and clinical issues are considered, and practical psychopharmacological recommendations and clinical guidelines are suggested.

  8. Mergers by Partial Acquisition


    Lindqvist, Tobias


    This paper evaluates partial acquisition strategies. The model allows for buying a share of a firm before the actual acquisition takes place. Holding a share in a competing firm before the acquisition of another firm, outsider-toehold, eliminates the insiders' dilemma, i.e. profitable mergers do not occur. This strategy may thus be more profitable for a buyer than acquiring entire firms at once. Furthermore, the insiders' dilemma arises from the assumption of a positive externality on the out...

  9. TECHNICAL TRAINING SEMINAR: National Instruments

    CERN Multimedia

    Monique Duval


    From 9:30 to 12:00 and from 13:00 to 16:00 hrs - Council Chamber, Salle B, Salle des Pas Perdus National Instruments (NI) on Tour 2004 Claudia Jüngel, Evrem Yarkin, Joel Clerc, Hervé Baour / NATIONAL INSTRUMENTS The special event NI on Tour 2004, run in Germany, Austria and Switzerland, will be at CERN on March 30. Technical seminars and free introductory courses will be offered all day long in the Council Chamber, Salle B, and Salle des Pas Perdus (buildings 61 and 503). Data acquisition systems on PCs, industrial measurement and control techniques, advanced LabVIEW software and PXI instrumentation, and system components for tests and automation will be presented. Walk-in courses will address DIAdem, LabVIEW and data acquisition. Language: English and French Free seminars and courses, no registration Organisers: Rolf Stampfli / IT-CO / 78102 & 160367 / Davide Vitè / HR-PMD-ATT / 75141 For more information and the complete event programme, please visit the...

  10. Instrumentation for multi-detector arrays

    Indian Academy of Sciences (India)


    Nov 27, 2015 ... The new generation of detector arrays require complex instrumentation and data acquisition system to ensure increased reliability of operation, high degree of integration, software control and faster data handling capability. The main features of some of the existing multi-detector arrays like MSU 4 array, ...

  11. Instrumentation for Power System Disturbance Monitoring, Data ...

    African Journals Online (AJOL)

    In this paper, the level of instrumentation for power system disturbance monitoring, data acquisition and control in Nigerian Electric Power System; National Electric Power Authority (NEPA) is presented. The need for accurate power system disturbance monitoring is highlighted. A feature of an adequate monitoring, data ...

  12. Acquisition of a Thermophoresis Instrument for Molecular Association Thermodynamic Studies (United States)


    were collected with a FluoroLog-3 spectrofluorometer (Horiba-Jobin-Yvon, Edison , NJ, USA). All samples were purged with argon prior to the...T.; Anvari, B.; Vullev, V. I. Chemical Science 2015, 6, 2237. (58) Thomas , M. S.; Nuñez, V.; Upadhyayula, S.; Zielins, E. R.; Bao, D.; Vasquez, J

  13. Acquisition Research Program Homepage



    Includes an image of the main page on this date and compressed file containing additional web pages. Established in 2003, Naval Postgraduate School’s (NPS) Acquisition Research Program provides leadership in innovation, creative problem solving and an ongoing dialogue, contributing to the evolution of Department of Defense acquisition strategies.

  14. Acquisition of teleological descriptions (United States)

    Franke, David W.


    Teleology descriptions capture the purpose of an entity, mechanism, or activity with which they are associated. These descriptions can be used in explanation, diagnosis, and design reuse. We describe a technique for acquiring teleological descriptions expressed in the teleology language TeD. Acquisition occurs during design by observing design modifications and design verification. We demonstrate the acquisition technique in an electronic circuit design.

  15. Robotization in Seismic Acquisition

    NARCIS (Netherlands)

    Blacquière, G.; Berkhout, A.J.


    The amount of sources and detectors in the seismic method follows "Moore’s Law of seismic data acquisition", i.e., it increases approximately by a factor of 10 every 10 years. Therefore automation is unavoidable, leading to robotization of seismic data acquisition. Recently, we introduced a new

  16. Philosophy of Psychopharmacology

    African Journals Online (AJOL)

    models of disorder. At the same time, he argues that “…we have to go beyond a natural science perspective e on the way the body and the brain work, to include also a consideration of human practices and values.” (p. 91). This is clearly relevant to the controversies surrounding the nature and treatment of mood disorders ...

  17. [Psychopharmacology and metabolic syndrome]. (United States)

    Telles-Correia, Diogo; Guerreiro, Diogo F; Coentre, Ricardo; Coentre, Rui; Góis, C; Figueira, Luísa


    Metabolic Syndrome consists in a group of metabolic changes, being the most important problem insulin resistence. Other important components of this syndrome are abdominal obesity, hypertension and hyperlipidemia /hypercholestrolemia. It was demonstrated that psychiatric patients have a greater risk to develop metabolic syndrome with a prevalence of 41%. Prevalence of this syndrome in psychiatric male patients is 138% higher than in general population and in female patients 251% higher. Some of the factors that can explain this increase of metabolic risk in psychiatric patients are psychiatric drugs. We preformed a systematic review of literature published until June, 2007, by means of MEDLINE. Studies reviewed include clinical cases, reviews, analytic and observational studies. We selected 72 articles. Authors pretend to understand the mechanisms, by which, different psychiatric drugs can influence metabolic syndrome, and strategies for prevention of this situation.

  18. Philosophy of Psychopharmacology

    African Journals Online (AJOL)

    2 For Stein, we can and must develop. “…sophisticated causal classifications of depression, based on a nuanced understanding of the interaction of biology and culture.” (p. 105). Yet Stein has a clear-eyed perspective on the deleterious effects ...

  19. Mergers and Acquisitions

    DEFF Research Database (Denmark)

    Risberg, Annette

    Introduction to the study of mergers and acquisitions. This book provides an understanding of the mergers and acquisitions process, how and why they occur, and also the broader implications for organizations. It presents issues including motives and planning, partner selection, integration......, employee experiences and communication. Mergers and acquisitions remain one of the most common forms of growth, yet they present considerable challenges for the companies and management involved. The effects on stakeholders, including shareholders, managers and employees, must be considered as well...... by editorial commentaries and reflects the important organizational and behavioural aspects which have often been ignored in the past. By providing this in-depth understanding of the mergers and acquisitions process, the reader understands not only how and why mergers and acquisitions occur, but also...

  20. Controls and data acquisition on Atlas

    Energy Technology Data Exchange (ETDEWEB)

    Scudder, D.W.; Hosack, K.W.; Parsons, W.M.; Reass, W.A.; Thompson, M.C.; Wysocki, F.J. [Los Alamos National Lab., NM (United States); Creager, J. [Allied Signal, Albuquerque, NM (United States)


    The control and data acquisition systems for Atlas will use a large degree of decentralization. By distributing control points close to the systems being controlled, the authors expect to simplify the task of isolating electronic systems from the large expected EMI pulses, allow connection of the various parts of the system by high-level fiber-optic networks, allow a simple configuration of the control and data acquisition screen rooms, and simplify the software efforts through the resulting modularization. The Atlas control system must control capacitor charging, machine and diagnostic timing and triggering, marx module diagnostics, vacuum systems, gas handling for railgaps, safety interlocks, and oil handling. Many of these tasks will be performed by industrial-style programmable logic controllers (PLCs). Each of 38 Marx bank maintenance units will have a control and diagnostic package which will monitor both charging and discharging current and railgap trigger timing. An unusual feature of digitizers to record each Marx module`s output waveform, plus nanosecond resolution time interval meters to record the firing time of each railgap. The machine data acquisition system for Atlas will be built around an SQL database, use National Instruments LabVIEW software to control data acquisition instruments and provide links for a variety of experimentalists` data analysis packages. World Wide Web access will provide an interface through which users can monitor experimental data and machine status.

  1. Introduction to the special issue: 50th anniversary of APA Division 28: The past, present, and future of psychopharmacology and substance abuse. (United States)

    Stoops, William W; Sigmon, Stacey C; Evans, Suzette M


    This is an introduction to the special issue "50th Anniversary of APA Division 28: The Past, Present, and Future of Psychopharmacology and Substance Abuse." Taken together, the scholarly contributions included in this special issue serve as a testament to the important work conducted by our colleagues over the past five decades. Division 28 and its members have advanced and disseminated knowledge on the behavioral effects of drugs, informed efforts to prevent and treat substance abuse, and influenced education and policy issues more generally. As past and current leaders of the division, we are excited to celebrate 50 years of Division 28 and look forward to many more successful decades for our division and its members. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  2. Interactive knowledge acquisition tools (United States)

    Dudziak, Martin J.; Feinstein, Jerald L.


    The problems of designing practical tools to aid the knowledge engineer and general applications used in performing knowledge acquisition tasks are discussed. A particular approach was developed for the class of knowledge acquisition problem characterized by situations where acquisition and transformation of domain expertise are often bottlenecks in systems development. An explanation is given on how the tool and underlying software engineering principles can be extended to provide a flexible set of tools that allow the application specialist to build highly customized knowledge-based applications.

  3. Indexing mergers and acquisitions


    Gang, Jianhua; Guo, Jie (Michael); Hu, Nan; Li, Xi


    We measure the efficiency of mergers and acquisitions by putting forward an index (the ‘M&A Index’) based on stochastic frontier analysis. The M&A Index is calculated for each takeover deal and is standardized between 0 and 1. An acquisition with a higher index encompasses higher efficiency. We find that takeover bids with higher M&A Indices are more likely to succeed. Moreover, the M&A Index shows a strong and positive relation with the acquirers’ post-acquisition stock perfo...

  4. Teaching Analytical Instrument Design with LabVIEW (United States)

    Gostowski, Rudy


    Chemists may be required to setup, troubleshoot, repair and sometimes construct the instruments they use for analytical measurements. Many students are intimidated when first "looking under the hood" of a modern instrument. This curriculum was devised to provide hands-on experience with the theory and design of modern instruments. A background in electronics is considered fundamental to this goal. This course extensively utilizes LabVIEW to economically provide basic electronic instrumentation and to serve in data acquisition and manipulation for a student design project. LabVIEW provides many built-in functions including a graphical user interface (GUI) and has universal acceptance in research and manufacturing settings. Programming is accomplished by placing and connecting icons that represent various functions. Virtual instruments produced by combining data acquisition boards with the language are functional equivalent to their real counterparts. The course culminates in construction of a computer-controlled electrochemical instrument capable of cyclic voltammetry and anodic stripping experiments.

  5. Holdup Measures on an SRNL Mossbauer Spectroscopy Instrument

    Energy Technology Data Exchange (ETDEWEB)

    Dewberry, R.; Brown, T.; Salaymeh, S.


    Gamma-ray holdup measurements of a Mossbauer spectroscopy instrument are described and modeled. In the qualitative acquisitions obtained in a low background area of Savannah River National Laboratory, only Am-241 and Np-237 activity were observed. The Am-241 was known to be the instrumental activation source, while the Np-237 is clearly observed as a source of contamination internal to the instrument. The two sources of activity are modeled separately in two acquisition configurations using two separate modeling tools. The results agree well, demonstrating a content of (1980 {+-} 150) {mu}Ci Am-241 and (110 {+-} 50) {mu}Ci of Np-237.

  6. Acquisition Workforce Annual Report 2006 (United States)

    General Services Administration — This is the Federal Acquisition Institute's (FAI's) Annual demographic report on the Federal acquisition workforce, showing trends by occupational series, employment...

  7. Acquisition Workforce Annual Report 2008 (United States)

    General Services Administration — This is the Federal Acquisition Institute's (FAI's) Annual demographic report on the Federal acquisition workforce, showing trends by occupational series, employment...



    Mariana Vancea


    Over the last few decades mergers and the acquisitions, both the international and thenational ones, have become strategic instruments of growth and development of enterprises. A sensibleaspect regarding the merger or the acquisition operations is that of integrating the entities had in view.Because it is considered that the high rate of the failure of the operations is due to unsuccessfulintegration of the entities, we have decided to identify the challenges occurring in this phase and thefa...

  9. FWS Approved Acquisition Boundaries (United States)

    US Fish and Wildlife Service, Department of the Interior — This data layer depicts the external boundaries of lands and waters that are approved for acquisition by the U.S. Fish and Wildlife Service (USFWS) in North America,...

  10. Documentation and knowledge acquisition (United States)

    Rochowiak, Daniel; Moseley, Warren


    Traditional approaches to knowledge acquisition have focused on interviews. An alternative focuses on the documentation associated with a domain. Adopting a documentation approach provides some advantages during familiarization. A knowledge management tool was constructed to gain these advantages.

  11. Acquisition IT Integration

    DEFF Research Database (Denmark)

    Henningsson, Stefan; Øhrgaard, Christian


    The IT integration of acquisitions consists an important challenge for the many acquiring organizations. Complementing existing research, this paper searches for explanation to differences in acquirers’ abilities for acquisition IT integration in the external of the acquirer, by a study of the use...... of temporary agency workers. Following an analytic induction approach, theoretically grounded in the re-source-based view of the firm, we identify the complimentary and supplementary roles consultants can assume in acquisition IT integration. Through case studies of three acquirers, we investigate how...... the acquirers appropriate the use of agency workers as part of its acquisition strategy. For the investigated acquirers, assigning roles to agency workers is contingent on balancing the needs of knowledge induction and knowledge retention, as well as experience richness and in-depth under-standing. Composition...

  12. Dorsal and ventral striatal protein synthesis inhibition affect reinforcer valuation but not the consolidation of instrumental learning. (United States)

    Jonkman, Sietse; Everitt, Barry J


    The evidence for a role of the striatum in the acquisition of uncued instrumental responding is ambiguous. It has been shown that post-session infusions of anisomycin into the core of the nucleus accumbens (NAcc) impaired instrumental acquisition, but pre-training lesions of the NAcc suggest that it is not necessary. Recently, we demonstrated that the infusion of anisomycin into the anterior cingulate cortex impaired instrumental acquisition indirectly through a taste aversion. Thus, we hypothesized that post-session anisomycin infusions into the NAcc affected instrumental acquisition through an effect on reinforcer valuation. For the dorsal striatum, both post-session infusions of anisomycin and pre-training lesion studies suggest that neither the dorsolateral nor the dorsomedial striatum is necessary for the acquisition of instrumental responding. However, it has not been attempted to block plasticity in both regions concurrently, and we hypothesized that both regions independently contribute to acquisition through goal-directed and habitual learning. In the current experiments, we first replicated the effect of unprotected post-session anisomycin infusions into the NAcc on instrumental acquisition. Subsequently, we investigated the effect of protein synthesis inhibition in the NAcc and dorsomedial and dorsolateral striatum concurrently on instrumental acquisition, critically controlling for effects on reinforcer valuation. The anisomycin infusions induced an aversive state, but did not affect instrumental acquisition.

  13. Post-Acquisition IT Integration

    DEFF Research Database (Denmark)

    Henningsson, Stefan; Yetton, Philip


    The extant research on post-acquisition IT integration analyzes how acquirers realize IT-based value in individual acquisitions. However, serial acquirers make 60% of acquisitions. These acquisitions are not isolated events, but are components in growth-by-acquisition programs. To explain how...... serial acquirers realize IT-based value, we develop three propositions on the sequential effects on post-acquisition IT integration in acquisition programs. Their combined explanation is that serial acquirers must have a growth-by-acquisition strategy that includes the capability to improve...... IT integration capabilities, to sustain high alignment across acquisitions and to maintain a scalable IT infrastructure with a flat or decreasing cost structure. We begin the process of validating the three propositions by investigating a longitudinal case study of a growth-by-acquisition program....

  14. Acquisition of Romance languages. Introduction


    Gavarró, Anna


    Generative grammar addressed for the first time acquisition as a central issue in the study of grammar. This perspective has given rise over the years to a considerable body of work, mainly on first language acquisition, but also on second language acquistion, bilingual acquisition, and the acquisition by children affected by SLI. If we assume continuity, i.e. that all stages in acquisition reflect possible natural languages, we must posit a mutual dependency between grammatical theory and th...

  15. IOT Overview: IR Instruments (United States)

    Mason, E.

    In this instrument review chapter the calibration plans of ESO IR instruments are presented and briefly reviewed focusing, in particular, on the case of ISAAC, which has been the first IR instrument at VLT and whose calibration plan served as prototype for the coming instruments.

  16. Astronomical Instruments in India (United States)

    Sarma, Sreeramula Rajeswara

    The earliest astronomical instruments used in India were the gnomon and the water clock. In the early seventh century, Brahmagupta described ten types of instruments, which were adopted by all subsequent writers with minor modifications. Contact with Islamic astronomy in the second millennium AD led to a radical change. Sanskrit texts began to lay emphasis on the importance of observational instruments. Exclusive texts on instruments were composed. Islamic instruments like the astrolabe were adopted and some new types of instruments were developed. Production and use of these traditional instruments continued, along with the cultivation of traditional astronomy, up to the end of the nineteenth century.

  17. Health physics instrument manual

    Energy Technology Data Exchange (ETDEWEB)

    Gupton, E.D.


    The purpose of this manual is to provide apprentice health physics surveyors and other operating groups not directly concerned with radiation detection instruments a working knowledge of the radiation detection and measuring instruments in use at the Laboratory. The characteristics and applications of the instruments are given. Portable instruments, stationary instruments, personnel monitoring instruments, sample counters, and miscellaneous instruments are described. Also, information sheets on calibration sources, procedures, and devices are included. Gamma sources, beta sources, alpha sources, neutron sources, special sources, a gamma calibration device for badge dosimeters, and a calibration device for ionization chambers are described. (WHK)

  18. Knowledge Transfers following Acquisition

    DEFF Research Database (Denmark)

    Gammelgaard, Jens


    study of 54 Danish acquisitions taking place abroad from 1994 to 1998 demonstrated that when there was a high level of trust between the acquiring firm and the target firm before the take-over, then medium and strong tie-binding knowledge transfer mechanisms, such as project groups and job rotation......Prior relations between the acquiring firm and the target company pave the way for knowledge transfers subsequent to the acquisitions. One major reason is that through the market-based relations the two actors build up mutual trust and simultaneously they learn how to communicate. An empirical...

  19. Instrumentation and Controls Division biennial progress report, September 1, 1974--September 1, 1976. Non-LMFBR programs

    Energy Technology Data Exchange (ETDEWEB)

    Sadowski, G.S. (comp.)


    Research progress and developments are reported in the areas of basic electronics, instruments, radiation monitoring, pulse counting and analysis, electronic engineering support for research facilities, automatic control and data acquisition, reactor instrumentation and controls, fuel reprocessing and shipping, process systems and instrumentation development, thermometry, instrumentation for reactor division experiments and test loops, environmental science studies, miscellaneous engineering studies, services, and developments, and maintenance. (WHK)

  20. Instrumentation and Controls Division biennial progress report, September 1, 1976--September 1, 1978

    Energy Technology Data Exchange (ETDEWEB)

    Sadowski, G.S. (ed.)


    Progress is summarized in the following research and development areas: electronic circuits;instruments; radiation monitoring; process systems and instrumentation; thermometry; instrumentation for engineering experiments and test loops; HTGR fuel recycle development; reactor measurements and analysis; automatic control and data acquisition; electronic engineering support for research facilities; miscellaneous engineering services, studies, and developments; maintenance; and environmental science studies.

  1. The Study on Virtual Medical Instrument based on LabVIEW. (United States)

    Chengwei, Li; Limei, Zhang; Xiaoming, Hu


    With the increasing performance of computer, the virtual instrument technology has greatly advanced over the years, and then virtual medical instrument technology becomes available. This paper presents the virtual medical instrument, and then as an example, an application of a signal acquisition, processing and analysis system using LabVIEW is also given.

  2. A Digital Data Acquisition for VANDLE (United States)

    Madurga, Miguel; Paulauskas, S.; Grzywacz, Robert; Miller, David; Padgett, Stephen; Tan, Hui


    Neutron energy measurements can be achieved using time-of-flight (ToF) techniques. A digital data acquisition system was developed for reliable ToF measurements with subnanosecond timing resolution based on digitizers with 10 ns and 4 ns sampling periods using pulse shape analysis algorithms. A validation procedure was developed to confirm the reliability. The response of the algorithm to photomultiplier signals was studied using a specially designed experimental system based on fast plastic scintillators. The presented developments enabled digital data acquisition systems to instrument the recently developed Versatile Array of Neutron Detectors at Low-Energy (VANDLE). This research was sponsored in part by the National Nuclear Security Administration under the Stewardship Science Academic Alliances program through DOE Cooperative Agreement No. DE-FG52-08NA28552 and the Office of Nuclear Physics.

  3. Autonomous Robot Skill Acquisition (United States)


    single demonstration using either a learned Hidden Markov Model (HMM) (Pook and Ballard, 1993; Hovland et al., 1996; Dixon and Khosla, 2004) or...of the Nineteenth International Conference on Machine Learning, pages 243– 250. Hovland , G., Sikka, P., and McCarragher, B. (1996). Skill acquisition

  4. Leading Acquisition Reform (United States)


    Army and Undersecretary of Defense for Acquisition, for a reduction of the Excalibur and Accelerated Precision Mortar initiative rounds.25...Can’t Dance? Leading a Great Enterprise Through Dramatic Change, (New York: HarperCollins Publishers, 2003), 235. 13 John P. Kotter , Leading Change

  5. Merger and acquisition medicine. (United States)

    Powell, G S


    This discussion of the ramifications of corporate mergers and acquisitions for employees recognizes that employee adaptation to the change can be a long and complex process. The author describes a role the occupational physician can take in helping to minimize the potential adverse health impact of major organizational change.

  6. Acquisition reconfiguration capability

    NARCIS (Netherlands)

    Amiryany Araghy, N.; Huysman, M.H.; de Man, A.P.; Cloodt, M.


    Purpose: Acquiring knowledge-intensive firms in order to gain access to their knowledge to innovate is not a strategy to achieve easily. Knowledge acquisitions demand that organizations integrate various dispersed knowledge-based resources and thus share knowledge to innovate. However, despite the

  7. Competencies: requirements and acquisition

    NARCIS (Netherlands)

    Kuenn, A.C.; Meng, C.M.; Peters, Z.; Verhagen, A.M.C.


    Higher education is given the key task to prepare the highly talented among the young to fulfil highly qualified roles in the labour market. Successful labour market performance of graduates is generally associated with the acquisition of the correct competencies. Education as an individual

  8. Surviving mergers & acquisitions. (United States)

    Dixon, Diane L


    Mergers and acquisitions are never easy to implement. The health care landscape is a minefield of failed mergers and uneasy alliances generating great turmoil and pain. But some mergers have been successful, creating health systems that benefit the communities they serve. Five prominent leaders offer their advice on minimizing the difficulties of M&As.

  9. Portable acquisition device AREVA; Dispositivo de adquisicion portatil de AREVA

    Energy Technology Data Exchange (ETDEWEB)

    Martin, H.; Izquierdo, J.


    The portable device of AREVA data acquisition arises as a solution to a need for modernization and updating of instrumentation tools and control which makes it more reliable, manageable and useful the data collection and further treatment, with an objective to minimize human error and effort, improving widely of course times.

  10. Acquisition And Utilisation Of Human Resources In Public ...

    African Journals Online (AJOL)

    The study examined the acquisition and utilisation of human resources in public secondary schools for students with special needs in Oyo State. The study employed a descriptive research design. The entire 196 teachers and 16 supportive staff formed the sample. The research instrument for the study was a questionnaire ...

  11. Dorsal and Dorsal and Ventral Striatal Protein Synthesis Inhibition Affect Reinforcer Valuation but Not the Consolidation of Instrumental Learning (United States)

    Jonkman, Sietse; Everitt, Barry J.


    The evidence for a role of the striatum in the acquisition of uncued instrumental responding is ambiguous. It has been shown that post-session infusions of anisomycin into the core of the nucleus accumbens (NAcc) impaired instrumental acquisition, but pre-training lesions of the NAcc suggest that it is not necessary. Recently, we demonstrated that…

  12. Industrial Products for Beam Instrumentation

    CERN Document Server

    Schmickler, Hermann


    In various branches of high technology industry there has been considerable progress in the past years which could be used for beam instrumentation. The subject will be introduced by two short demonstrations: a demonstration of modern audio electronics with 24bit-96kHz ADC, digital signal electronics and application programs under windows on a PC, which allow to change the parameters of the signal treatment. Potential applications are data monitoring at constant sampling frequency, orbit feedbacks (including high power audio amplifiers), noise reduction on beam current transformers... digital treatment of video signals webcams, frame grabbers, CCD-data via USB, all one needs for image acquisitions, in particular interesting for profile measurements. These introductory demonstrations will not last longer than 30 minutes. The remaining time will be used to pass through the audience collecting information into a two dimensional table, which shall contain as row index the accelerator and as column index the t...

  13. 10 CFR 1015.103 - Antitrust, fraud, tax, interagency, transportation account audit, acquisition contract, and... (United States)


    ... General § 1015.103 Antitrust, fraud, tax, interagency, transportation account audit, acquisition contract... 10 Energy 4 2010-01-01 2010-01-01 false Antitrust, fraud, tax, interagency, transportation account audit, acquisition contract, and financial assistance instrument claims excluded. 1015.103 Section 1015...


    Directory of Open Access Journals (Sweden)

    Amelia-Raluca ONIŞOR


    Full Text Available The research analyses the legal effects of mergers and acquisitions from the Romanian Company Law perspective, underlining certain general principles, the procedure of annulment of such a legal transformation of companies and the protection of the employees of companies participating in the merger according to the Law no. 67/2006. These consequences of mergers and acquisions are to be seen in the broader light of the most important purpose of this legal instrument, maximizing financial and organizational efficiencies, thus legal certainty is a desirable goal to be assumed by any merger regulation.

  15. RF merger and acquisition market


    Evgeniya V. Vidishcheva; Merab S. Sichinava; Marina V. Kogan


    The article gives brief characteristic of merger and acquisition market situation in Russia, brings in overview of bargains in 2009–2010. Russian merger and acquisition market is in early stage of development.

  16. RF merger and acquisition market

    Directory of Open Access Journals (Sweden)

    Evgeniya V. Vidishcheva


    Full Text Available The article gives brief characteristic of merger and acquisition market situation in Russia, brings in overview of bargains in 2009–2010. Russian merger and acquisition market is in early stage of development.

  17. Instrument Modeling and Synthesis (United States)

    Horner, Andrew B.; Beauchamp, James W.

    During the 1970s and 1980s, before synthesizers based on direct sampling of musical sounds became popular, replicating musical instruments using frequency modulation (FM) or wavetable synthesis was one of the “holy grails” of music synthesis. Synthesizers such as the Yamaha DX7 allowed users great flexibility in mixing and matching sounds, but were notoriously difficult to coerce into producing sounds like those of a given instrument. Instrument design wizards practiced the mysteries of FM instrument design.

  18. Amplitudes, acquisition and imaging

    Energy Technology Data Exchange (ETDEWEB)

    Bloor, Robert


    Accurate seismic amplitude information is important for the successful evaluation of many prospects and the importance of such amplitude information is increasing with the advent of time lapse seismic techniques. It is now widely accepted that the proper treatment of amplitudes requires seismic imaging in the form of either time or depth migration. A key factor in seismic imaging is the spatial sampling of the data and its relationship to the imaging algorithms. This presentation demonstrates that acquisition caused spatial sampling irregularity can affect the seismic imaging and perturb amplitudes. Equalization helps to balance the amplitudes, and the dealing strategy improves the imaging further when there are azimuth variations. Equalization and dealiasing can also help with the acquisition irregularities caused by shot and receiver dislocation or missing traces. 2 refs., 2 figs.

  19. The Instrumental Model (United States)

    Yeates, Devin Rodney


    The goal of this dissertation is to enable better predictive models by engaging raw experimental data through the Instrumental Model. The Instrumental Model captures the protocols and procedures of experimental data analysis. The approach is formalized by encoding the Instrumental Model in an XML record. Decoupling the raw experimental data from…

  20. Aeroacoustics of Musical Instruments

    NARCIS (Netherlands)

    Fabre, B.; Gilbert, J.; Hirschberg, Abraham; Pelorson, X.


    We are interested in the quality of sound produced by musical instruments and their playability. In wind instruments, a hydrodynamic source of sound is coupled to an acoustic resonator. Linear acoustics can predict the pitch of an instrument. This can significantly reduce the trial-and-error process

  1. Conjoined Constraints and Phonological Acquisition

    Directory of Open Access Journals (Sweden)

    Giovana Bonilha


    Full Text Available Since the start of Optimality Theory (Prince & Smolensky, 1993, research on phonological acquisition has explored the explanatory potential of constraint theories. This study, also based on Optimality Theory, attempts to analyze the acquisition of CVVC syllable structure by Brazilian Portuguese children and addresses the issue of Local Conjunction (Smolensky, 1995, 1997 in research that deals with problems of phonological acquisition.

  2. First Language Acquisition and Teaching (United States)

    Cruz-Ferreira, Madalena


    "First language acquisition" commonly means the acquisition of a single language in childhood, regardless of the number of languages in a child's natural environment. Language acquisition is variously viewed as predetermined, wondrous, a source of concern, and as developing through formal processes. "First language teaching" concerns schooling in…

  3. Internationalize Mergers and Acquisitions


    Zhou, Lili


    As globalization processes, an increasing number of companies use mergers and acquisitions as a tool to achieve company growth in the international business world. The purpose of this thesis is to investigate the process of an international M&A and analyze the factors leading to success. The research started with reviewing different academic theory. The important aspects in both pre-M&A phase and post-M&A phase have been studied in depth. Because of the complexity in international...

  4. Competencies: requirements and acquisition


    Kuenn, A.C.; Meng, C.M.; Peters, Z.; Verhagen, A.M.C.


    Higher education is given the key task to prepare the highly talented among the young to fulfil highly qualified roles in the labour market. Successful labour market performance of graduates is generally associated with the acquisition of the correct competencies. Education as an individual investment in human capital is a viewpoint dating back to the 17th century and the writings of Sir William Petty (1662), and includes later work by Adam Smith (1776). The idea was formalized and brought in...

  5. Second language acquisition. (United States)

    Juffs, Alan


    Second language acquisition (SLA) is a field that investigates child and adult SLA from a variety of theoretical perspectives. This article provides a survey of some key areas of concern including formal generative theory and emergentist theory in the areas of morpho-syntax and phonology. The review details the theoretical stance of the two different approaches to the nature of language: generative linguistics and general cognitive approaches. Some results of key acquisition studies from the two theoretical frameworks are discussed. From a generative perspective, constraints on wh-movement, feature geometry and syllable structure, and morphological development are highlighted. From a general cognitive point of view, the emergence of tense and aspect marking from a prototype account of inherent lexical aspect is reviewed. Reference is made to general cognitive learning theories and to sociocultural theory. The article also reviews individual differences research, specifically debate on the critical period in adult language acquisition, motivation, and memory. Finally, the article discusses the relationship between SLA research and second language pedagogy. Suggestions for further reading from recent handbooks on SLA are provided. WIREs Cogni Sci 2011 2 277-286 DOI: 10.1002/wcs.106 For further resources related to this article, please visit the WIREs website. Copyright © 2010 John Wiley & Sons, Ltd.

  6. Complexity in language acquisition. (United States)

    Clark, Alexander; Lappin, Shalom


    Learning theory has frequently been applied to language acquisition, but discussion has largely focused on information theoretic problems-in particular on the absence of direct negative evidence. Such arguments typically neglect the probabilistic nature of cognition and learning in general. We argue first that these arguments, and analyses based on them, suffer from a major flaw: they systematically conflate the hypothesis class and the learnable concept class. As a result, they do not allow one to draw significant conclusions about the learner. Second, we claim that the real problem for language learning is the computational complexity of constructing a hypothesis from input data. Studying this problem allows for a more direct approach to the object of study--the language acquisition device-rather than the learnable class of languages, which is epiphenomenal and possibly hard to characterize. The learnability results informed by complexity studies are much more insightful. They strongly suggest that target grammars need to be objective, in the sense that the primitive elements of these grammars are based on objectively definable properties of the language itself. These considerations support the view that language acquisition proceeds primarily through data-driven learning of some form. Copyright © 2013 Cognitive Science Society, Inc.

  7. Performing the Super Instrument

    DEFF Research Database (Denmark)

    Kallionpaa, Maria


    The genre of contemporary classical music has seen significant innovation and research related to new super, hyper, and hybrid instruments, which opens up a vast palette of expressive potential. An increasing number of composers, performers, instrument designers, engineers, and computer programmers...... have become interested in different ways of “supersizing” acoustic instruments in order to open up previously-unheard instrumental sounds. Super instruments vary a great deal but each has a transformative effect on the identity and performance practice of the performing musician. Furthermore, composers...... provides the performer extensive virtuoso capabilities in terms of instrumental range, harmony, timbre, or spatial, textural, acoustic, technical, or technological qualities. The discussion will be illustrated by a composition case study involving augmented musical instrument electromagnetic resonator...

  8. The NUSTAR data acquisition

    Energy Technology Data Exchange (ETDEWEB)

    Loeher, B.; Toernqvist, H.T. [TU Darmstadt (Germany); GSI (Germany); Agramunt, J. [IFIC, CSIC (Spain); Bendel, M.; Gernhaeuser, R.; Le Bleis, T.; Winkel, M. [TU Muenchen (Germany); Charpy, A.; Heinz, A.; Johansson, H.T. [Chalmers University of Technology (Sweden); Coleman-Smith, P.; Lazarus, I.H.; Pucknell, V.F.E. [STFC Daresbury (United Kingdom); Czermak, A. [IFJ (Poland); Kurz, N.; Nociforo, C.; Pietri, S.; Schaffner, H.; Simon, H. [GSI (Germany); Scheit, H. [TU Darmstadt (Germany); Taieb, J. [CEA (France)


    The diversity of upcoming experiments within the NUSTAR collaboration, including experiments in storage rings, reactions at relativistic energies and high-precision spectroscopy, is reflected in the diversity of the required detection systems. A challenging task is to incorporate the different needs of individual detectors within the unified NUSTAR Data AcQuisition (NDAQ). NDAQ takes up this challenge by providing a high degree of availability via continuously running systems, high flexibility via experiment-specific configuration files for data streams and trigger logic, distributed timestamps and trigger information on km distances, all built on the solid basis of the GSI Multi-Branch System. NDAQ ensures interoperability between individual NUSTAR detectors and allows merging of formerly separate data streams according to the needs of all experiments, increasing reliability in NUSTAR data acquisition. An overview of the NDAQ infrastructure and the current progress is presented. The NUSTAR (NUclear STructure, Astrophysics and Reactions) collaboration represents one of the four pillars motivating the construction of the international FAIR facility. The diversity of NUSTAR experiments, including experiments in storage rings, reactions at relativistic energies and high-precision spectroscopy, is reflected in the diversity of the required detection systems. A challenging task is to incorporate the different needs of individual detectors and components under the umbrella of the unified NUSTAR Data AQuisition (NDAQ) infrastructure. NDAQ takes up this challenge by providing a high degree of availability via continuously running systems, high flexibility via experiment-specific configuration files for data streams and trigger logic, and distributed time stamps and trigger information on km distances, all built on the solid basis of the GSI Multi-Branch System (MBS). NDAQ ensures interoperability between individual NUSTAR detectors and allows merging of formerly separate

  9. First language acquisition. (United States)

    Goodluck, Helen


    This article reviews current approaches to first language acquisition, arguing in favor of the theory that attributes to the child an innate knowledge of universal grammar. Such knowledge can accommodate the systematic nature of children's non-adult linguistic behaviors. The relationships between performance devices (mechanisms for comprehension and production of speech), non-linguistic aspects of cognition, and child grammars are also discussed. WIREs Cogn Sci 2011 2 47-54 DOI: 10.1002/wcs.95 For further resources related to this article, please visit the WIREs website. Copyright © 2010 John Wiley & Sons, Ltd.

  10. Implementation of High Speed Distributed Data Acquisition System (United States)

    Raju, Anju P.; Sekhar, Ambika


    This paper introduces a high speed distributed data acquisition system based on a field programmable gate array (FPGA). The aim is to develop a "distributed" data acquisition interface. The development of instruments such as personal computers and engineering workstations based on "standard" platforms is the motivation behind this effort. Using standard platforms as the controlling unit allows independence in hardware from a particular vendor and hardware platform. The distributed approach also has advantages from a functional point of view: acquisition resources become available to multiple instruments; the acquisition front-end can be physically remote from the rest of the instrument. High speed data acquisition system transmits data faster to a remote computer system through Ethernet interface. The data is acquired through 16 analog input channels. The input data commands are multiplexed and digitized and then the data is stored in 1K buffer for each input channel. The main control unit in this design is the 16 bit processor implemented in the FPGA. This 16 bit processor is used to set up and initialize the data source and the Ethernet controller, as well as control the flow of data from the memory element to the NIC. Using this processor we can initialize and control the different configuration registers in the Ethernet controller in a easy manner. Then these data packets are sending to the remote PC through the Ethernet interface. The main advantages of the using FPGA as standard platform are its flexibility, low power consumption, short design duration, fast time to market, programmability and high density. The main advantages of using Ethernet controller AX88796 over others are its non PCI interface, the presence of embedded SRAM where transmit and reception buffers are located and high-performance SRAM-like interface. The paper introduces the implementation of the distributed data acquisition using FPGA by VHDL. The main advantages of this system are high

  11. Instrumentation a reader

    CERN Document Server

    Pope, P


    This book contains a selection of papers and articles in instrumentation previously pub­ lished in technical periodicals and journals of learned societies. Our selection has been made to illustrate aspects of current practice and applications of instrumentation. The book does not attempt to be encyclopaedic in its coverage of the subject, but to provide some examples of general transduction techniques, of the sensing of particular measurands, of components of instrumentation systems and of instrumentation practice in two very different environments, the food industry and the nuclear power industry. We have made the selection particularly to provide papers appropriate to the study of the Open University course T292 Instrumentation. The papers have been chosen so that the book covers a wide spectrum of instrumentation techniques. Because of this, the book should be of value not only to students of instrumen­ tation, but also to practising engineers and scientists wishing to glean ideas from areas of instrumen...

  12. Continued Data Acquisition Development

    Energy Technology Data Exchange (ETDEWEB)

    Schwellenbach, David [National Security Technologies, LLC. (NSTec), Mercury, NV (United States)


    This task focused on improving techniques for integrating data acquisition of secondary particles correlated in time with detected cosmic-ray muons. Scintillation detectors with Pulse Shape Discrimination (PSD) capability show the most promise as a detector technology based on work in FY13. Typically PSD parameters are determined prior to an experiment and the results are based on these parameters. By saving data in list mode, including the fully digitized waveform, any experiment can effectively be replayed to adjust PSD and other parameters for the best data capture. List mode requires time synchronization of two independent data acquisitions (DAQ) systems: the muon tracker and the particle detector system. Techniques to synchronize these systems were studied. Two basic techniques were identified: real time mode and sequential mode. Real time mode is the preferred system but has proven to be a significant challenge since two FPGA systems with different clocking parameters must be synchronized. Sequential processing is expected to work with virtually any DAQ but requires more post processing to extract the data.

  13. Unsupervised Language Acquisition (United States)

    de Marcken, Carl


    This thesis presents a computational theory of unsupervised language acquisition, precisely defining procedures for learning language from ordinary spoken or written utterances, with no explicit help from a teacher. The theory is based heavily on concepts borrowed from machine learning and statistical estimation. In particular, learning takes place by fitting a stochastic, generative model of language to the evidence. Much of the thesis is devoted to explaining conditions that must hold for this general learning strategy to arrive at linguistically desirable grammars. The thesis introduces a variety of technical innovations, among them a common representation for evidence and grammars, and a learning strategy that separates the ``content'' of linguistic parameters from their representation. Algorithms based on it suffer from few of the search problems that have plagued other computational approaches to language acquisition. The theory has been tested on problems of learning vocabularies and grammars from unsegmented text and continuous speech, and mappings between sound and representations of meaning. It performs extremely well on various objective criteria, acquiring knowledge that causes it to assign almost exactly the same structure to utterances as humans do. This work has application to data compression, language modeling, speech recognition, machine translation, information retrieval, and other tasks that rely on either structural or stochastic descriptions of language.

  14. Networked Instrumentation Element (United States)

    National Aeronautics and Space Administration — Armstrong researchers have developed a networked instrumentation system that connects modern experimental payloads to existing analog and digital communications...

  15. Ocean Optics Instrumentation Systems (United States)

    Federal Laboratory Consortium — FUNCTION: Provides instrumentation suites for a wide variety of measurements to characterize the ocean’s optical environment. These packages have been developed to...

  16. Determinants of Instrumental Extinction in Terrestrial Toads ("Bufo arenarum") (United States)

    Muzio, Ruben N.; Ruetti, Eliana; Papini, Mauricio R.


    Previous research in a water-reinforced instrumental training situation with toads ("Bufo arenarum") has shown that performance in both acquisition and extinction is poorer after partial, rather than continuous reinforcement training. In Experiment 1, the performance of a group receiving 24 trials on a 50% partial reinforcement schedule was poorer…

  17. 31 CFR 800.206 - Convertible voting instrument. (United States)


    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Convertible voting instrument. 800.206 Section 800.206 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF INVESTMENT SECURITY, DEPARTMENT OF THE TREASURY REGULATIONS PERTAINING TO MERGERS, ACQUISITIONS...

  18. Target Acquisition Methodology Enhancement (TAME) (United States)


    acquisition probability from COMINT, PCOM , against all communications type targets, is determined offline by a stochastic model for subsequent...of PN over all replications. F-4 f. Computes overall acquisition probability, PCOM , against all communications type targets as C: PCOM = (1. - PN...NNET where NNET denotes the number of nets which the target is in. F-6. TOTAL ACQUISITION PROBABILITY. With PNCj and PCOM computed as above, the

  19. Collection assessment and acquisitions budgets

    CERN Document Server

    Lee, Sul H


    This invaluable new book contains timely information about the assessment of academic library collections and the relationship of collection assessment to acquisition budgets. The rising cost of information significantly influences academic libraries'abilities to acquire the necessary materials for students and faculty, and public libraries'abilities to acquire material for their clientele. Collection Assessment and Acquisitions Budgets examines different aspects of the relationship between the assessment of academic library collections and the management of library acquisition budgets. Librar

  20. Parallel Spectral Acquisition with an Ion Cyclotron Resonance Cell Array. (United States)

    Park, Sung-Gun; Anderson, Gordon A; Navare, Arti T; Bruce, James E


    Mass measurement accuracy is a critical analytical figure-of-merit in most areas of mass spectrometry application. However, the time required for acquisition of high-resolution, high mass accuracy data limits many applications and is an aspect under continual pressure for development. Current efforts target implementation of higher electrostatic and magnetic fields because ion oscillatory frequencies increase linearly with field strength. As such, the time required for spectral acquisition of a given resolving power and mass accuracy decreases linearly with increasing fields. Mass spectrometer developments to include multiple high-resolution detectors that can be operated in parallel could further decrease the acquisition time by a factor of n, the number of detectors. Efforts described here resulted in development of an instrument with a set of Fourier transform ion cyclotron resonance (ICR) cells as detectors that constitute the first MS array capable of parallel high-resolution spectral acquisition. ICR cell array systems consisting of three or five cells were constructed with printed circuit boards and installed within a single superconducting magnet and vacuum system. Independent ion populations were injected and trapped within each cell in the array. Upon filling the array, all ions in all cells were simultaneously excited and ICR signals from each cell were independently amplified and recorded in parallel. Presented here are the initial results of successful parallel spectral acquisition, parallel mass spectrometry (MS) and MS/MS measurements, and parallel high-resolution acquisition with the MS array system.

  1. Instrumentation Design and Development Facilities (United States)

    Federal Laboratory Consortium — RTTC has facilities for design, development and fabrication of: custominstrumentation, mobile instrumentation, miniaturized instrumentation, wirelessinstrumentation,...

  2. Sterilization of endoscopic instruments. (United States)

    Sabnis, Ravindra B; Bhattu, Amit; Vijaykumar, Mohankumar


    Sterilization of endoscopic instruments is an important but often ignored topic. The purpose of this article is to review the current literature on the sterilization of endoscopic instruments and elaborate on the appropriate sterilization practices. Autoclaving is an economic and excellent method of sterilizing the instruments that are not heat sensitive. Heat sensitive instruments may get damaged with hot sterilization methods. Several new endoscopic instruments such as flexible ureteroscopes, chip on tip endoscopes, are added in urologists armamentarium. Many of these instruments are heat sensitive and hence alternative efficacious methods of sterilization are necessary. Although ethylene oxide and hydrogen peroxide are excellent methods of sterilization, they have some drawbacks. Gamma irradiation is mainly for disposable items. Various chemical agents are widely used even though they achieve high-level disinfection rather than sterilization. This article reviews various methods of endoscopic instrument sterilization with their advantages and drawbacks. If appropriate sterilization methods are adopted, then it not only will protect patients from procedure-related infections but prevent hypersensitive allergic reactions. It will also protect instruments from damage and increase its longevity.

  3. Creating a Super Instrument

    DEFF Research Database (Denmark)

    Kallionpää, Maria; Gasselseder, Hans-Peter


    traditionally been dependent on their existing instrumental skills, various technological solutions can be used to reach beyond them. This paper focuses on the possibilities of enhancing composers' and performing pianists' technical and expressive vocabulary in the context of electroacoustic super instrument...

  4. Data Acquisition Systems course

    CERN Multimedia

    CERN. Geneva HR-RFA


    We will review the main physics and operational requirements on the Trigger and Data Acquisition (DAQ) systems of the LHC experiments. A description of the architecture of the various systems, the motivation of each alternative and the conceptual design of each filtering stage will be discussed. We will then turn to a description of the major elements of the three distinct sub-systems, namely the Level-1 trigger, the DAQ with its event-building and overall control and monitor, and finally the High-Level trigger system and the online processor farms. The thrust of the two lectures will be to provide a "broad brush" picture of the functionality of these systems.

  5. Theories of language acquisition. (United States)

    Vetter, H J; Howell, R W


    Prior to the advent of generative grammar, theoretical approaches to language development relied heavily upon the concepts ofdifferential reinforcement andimitation. Current studies of linguistic acquisition are largely dominated by the hypothesis that the child constructs his language on the basis of a primitive grammar which gradually evolves into a more complex grammar. This approach presupposes that the investigator does not impose his own grammatical rules on the utterances of the child; that the sound system of the child and the rules he employs to form sentences are to be described in their own terms, independently of the model provided by the adult linguistic community; and that there is a series of steps or stages through which the child passes on his way toward mastery of the adult grammar in his linguistic environment. This paper attempts to trace the development of human vocalization through prelinguistic stages to the development of what can be clearly recognized as language behavior, and then progresses to transitional phases in which the language of the child begins to approximate that of the adult model. In the view of the authors, the most challenging problems which confront theories of linguistic acquisition arise in seeking to account for structure of sound sequences, in the rules that enable the speaker to go from meaning to sound and which enable the listener to go from sound to meaning. The principal area of concern for the investigator, according to the authors, is the discovery of those rules at various stages of the learning process. The paper concludes with a return to the question of what constitutes an adequate theory of language ontogenesis. It is suggested that such a theory will have to be keyed to theories of cognitive development and will have to include and go beyond a theory which accounts for adult language competence and performance, since these represent only the terminal stage of linguistic ontogenesis.

  6. How Much of Language Acquisition Does Operant Conditioning Explain?

    Directory of Open Access Journals (Sweden)

    Christopher B. Sturdy


    Full Text Available Since the 1950s, when Chomsky argued that Skinner’s arguments could not explain syntactic acquisition, psychologists have generally avoided explicitly invoking operant or instrumental conditioning as a learning mechanism for language among human children. In this article, we argue that this is a mistake. We focus on research that has been done on language learning in human infants and toddlers in order to illustrate our points. Researchers have ended up inventing learning mechanisms that, in actual practice, not only resemble but also in fact are examples of operant conditioning (OC by any other name they select. We argue that language acquisition researchers should proceed by first ruling out OC before invoking alternative learning mechanisms. While it is possible that OC cannot explain all of the language acquisition, simple learning mechanisms that work across species may have some explanatory power in children’s language learning.

  7. How Much of Language Acquisition Does Operant Conditioning Explain? (United States)

    Sturdy, Christopher B; Nicoladis, Elena


    Since the 1950s, when Chomsky argued that Skinner's arguments could not explain syntactic acquisition, psychologists have generally avoided explicitly invoking operant or instrumental conditioning as a learning mechanism for language among human children. In this article, we argue that this is a mistake. We focus on research that has been done on language learning in human infants and toddlers in order to illustrate our points. Researchers have ended up inventing learning mechanisms that, in actual practice, not only resemble but also in fact are examples of operant conditioning (OC) by any other name they select. We argue that language acquisition researchers should proceed by first ruling out OC before invoking alternative learning mechanisms. While it is possible that OC cannot explain all of the language acquisition, simple learning mechanisms that work across species may have some explanatory power in children's language learning.

  8. ISOTDAQ - where students learn about trigger and data acquisition

    CERN Multimedia

    CERN Bulletin


    Where can students learn to implement a good trigger and to design the data acquisition system for today’s increasingly complex experiments? Universities rarely include classes on such specific topics. The ISOTDAQ School trains students and helps them gain hands-on experience of trigger systems, data-acquisition hardware and software, and data-transfer technologies.   One of the commercially available FPGA development boards from Altera. This was used in one of the practical exercises at ISOTDAQ2011 to teach students the principles of FPGA programming. The second International School of Trigger and Data Acquisition (ISOTDAQ) was held from 9 to 16 February at the Physics Department of Rome University, ‘La Sapienza’. The School was jointly organised and sponsored by CERN, INFN, ACEOLE (a Marie Curie Initial Training Network at CERN), and National Instruments. This year almost fifty students took part in the School. “Leading experts in the field gave lectures ...

  9. Portable calibration instrument of hemodialysis unit (United States)

    Jin, Liang-bing; Li, Dong-sheng; Chen, Ai-jun


    For the purpose of meeting the rapid development of blood purification in China, improve the level of blood purification treatment, and get rid of the plight of the foreign technology monopolization to promise patients' medical safety, a parameter-calibrator for the hemodialysis unit, which can detect simultaneously multi-parameter, is designed. The instrument includes a loop, which connects to the hemodialysis unit. Sensors are in the loop in series, so that the dialysis can flow through this loop and the sensors can acquisitive data of various parameters. In order to facilitate detection and carrying, the integrated circuit part modularly based on the ultralow-power microcontrollers,TI MSP430 is designed. High-performance and small-packaged components are used to establish a modular, high-precision, multi-functional, portable system. The functions and the key technical indexes of the instrument have reached the level of products abroad.

  10. Virtual Instrument for Modelling and Measuring the Distorting State

    Directory of Open Access Journals (Sweden)

    Katalin ÁGOSTON


    Full Text Available This paper presents a virtual instrument developed in LabView for modeling generating a distorting voltage by adding harmonics with different level and phase to the base signal. The other virtual instrument models the single-phase power system and calculates the power and energy proper to the harmonics. The virtual instrument can be enlarged very easy for three-phase power system. Developing proper conditional circuits for current and voltage acquisition the virtual instrument can be modify to measure real data. The designed virtual instrument calculates from the acquired data the active and reactive power, the power factor and the frequency and level of the harmonics in case of nonsinusoidal signals.

  11. Biological Constraints on Literacy Acquisition. (United States)

    Cossu, Giuseppe


    Investigates some of the biological constraints that shape the process of literacy acquisition. Explores the possibility of isolating processing components of reading which correspond to computational units of equivalent size in the neural architecture. Suggests that the process of literacy acquisition is largely constrained by a specific…

  12. Foreign Acquisition, Wages and Productivity

    DEFF Research Database (Denmark)

    Bandick, Roger


    This paper studies the effect of foreign acquisition on wages and total factor productivity (TFP) in the years following a takeover by using unique detailed firm-level data for Sweden for the period 1993-2002. The paper takes particular account of the potential endogeneity of the acquisition...

  13. Foreign Acquisition, Wages and Productivity

    DEFF Research Database (Denmark)

    Bandick, Roger

    This paper studies the effect of foreign acquisition on wages and total factor productivity (TFP) in the years following a takeover by using unique detailed firm-level data for Sweden for the period 1993-2002. The paper takes particular account of the potential endogeneity of the acquisition...

  14. Defense Acquisition Performance Assessment Report (United States)


    Development – “Acquisition Reform and Interoperability” BARTLeTT, ROsALiND , Analyst, Office of the Deputy Assistant Secretary of the Navy for Acquisition...Managers Performance Review” FRANKLiN , CHARLes, Vice-President, Raytheon Company Evaluation Team – “Corporate Perspective” FRANKLiN , RuTH W., Director

  15. Instrumentation reference book

    CERN Document Server

    Boyes, Walt


    Instrumentation is not a clearly defined subject, having a 'fuzzy' boundary with a number of other disciplines. Often categorized as either 'techniques' or 'applications' this book addresses the various applications that may be needed with reference to the practical techniques that are available for the instrumentation or measurement of a specific physical quantity or quality. This makes it of direct interest to anyone working in the process, control and instrumentation fields where these measurements are essential.* Comprehensive and authoritative collection of technical information* Writte

  16. Developing Acquisition IS Integration Capabilities

    DEFF Research Database (Denmark)

    Wynne, Peter J.


    An under researched, yet critical challenge of Mergers and Acquisitions (M&A), is what to do with the two organisations’ information systems (IS) post-acquisition. Commonly referred to as acquisition IS integration, existing theory suggests that to integrate the information systems successfully......, an acquiring company must leverage two high level capabilities: diagnosis and integration execution. Through a case study, this paper identifies how a novice acquirer develops these capabilities in anticipation of an acquisition by examining its use of learning processes. The study finds the novice acquirer...... applies trial and error, experimental, and vicarious learning processes, while actively avoiding improvisational learning. The results of the study contribute to the acquisition IS integration literature specifically by exploring it from a new perspective: the learning processes used by novice acquirers...

  17. Self-management of psychiatric symptoms using over-the-counter (OTC) psychopharmacology: the S-DTM therapeutic model--Self-diagnosis, self-treatment, self-monitoring. (United States)

    Charlton, Bruce G


    Pharmacological self-management is becoming more widespread in modernizing societies, as part of a general expansion of health care. This may exert a vital corrective balance to the professionalization of health by ensuring that the individual perspective of patients is not neglected. There are many 'good ideas' for new treatments being published which have a plausible scientific rationale for effectiveness and a low likelihood of harm, yet are essentially ignored by mainstream medical research. The most likely avenue for progress is probably the spread of self-management, together with increased sharing of experience via the internet. There is considerable scope for self-management of psychiatric symptoms with psychoactive medication purchased 'over-the-counter' (OTC) and without prescription. A surprisingly wide range of effective psychoactive agents are available with the potential to self-treat many of the common psychiatric problems. These include 'medical' psychopharmacological agents such as analgesics and antihistamines, a plant extract called St. John's Wort (Hypericum), and physical treatments such as early morning bright light therapy. But self-management currently lacks an explicit therapeutic model. A three stage process of S-DTM - self-diagnosis, self-treatment and self-monitoring is proposed and described in relation to psychiatric symptoms. Self-diagnosis describes the skill of introspection to develop awareness of inner bodily states and emotions. A specific sensation is identified and isolated as the 'focal symptom' for subsequent treatment and monitoring. Self-treatment involves choosing a drug (or other therapy) which is intended to alleviate the focal symptom. Self-monitoring entails a continued awareness of the focal system and of general well-being in order to evaluate effect of therapy. Self-monitoring could involve repeated cycles of dose-adjustment, and on-off ('challenge-dechallenge-rechallenge') therapeutic trials. An example of S

  18. V4: The Small Angle Scattering Instrument (SANS at BER II

    Directory of Open Access Journals (Sweden)

    Uwe Keiderling


    Full Text Available V4 is a small-angle neutron scatting instrument with an accessible range of scattering vector 0.01 nm-1 < Q < 8.5 nm-1. Outstanding features of the instrument are the polarized neutron option and the list mode data acquisition, allowing for time-resolved measurements with µs time resolution.

  19. 48 CFR 873.105 - Acquisition planning. (United States)


    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Acquisition planning. 873.105 Section 873.105 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS DEPARTMENT... planning. (a) Acquisition planning is an indispensable component of the total acquisition process. (b) For...

  20. 48 CFR 234.004 - Acquisition strategy. (United States)


    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Acquisition strategy. 234..., DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION 234.004 Acquisition strategy. (1) See 209.570 for policy applicable to acquisition strategies that consider the use of lead system...

  1. 48 CFR 34.004 - Acquisition strategy. (United States)


    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Acquisition strategy. 34... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION General 34.004 Acquisition strategy. The program manager, as specified in agency procedures, shall develop an acquisition strategy tailored to the particular...

  2. 48 CFR 3034.004 - Acquisition strategy. (United States)


    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Acquisition strategy. 3034.004 Section 3034.004 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND... Acquisition strategy. See (HSAR) 48 CFR 3009.570 for policy applicable to acquisition strategies that consider...

  3. FPGA Flash Memory High Speed Data Acquisition (United States)

    Gonzalez, April


    The purpose of this research is to design and implement a VHDL ONFI Controller module for a Modular Instrumentation System. The goal of the Modular Instrumentation System will be to have a low power device that will store data and send the data at a low speed to a processor. The benefit of such a system will give an advantage over other purchased binary IP due to the capability of allowing NASA to re-use and modify the memory controller module. To accomplish the performance criteria of a low power system, an in house auxiliary board (Flash/ADC board), FPGA development kit, debug board, and modular instrumentation board will be jointly used for the data acquisition. The Flash/ADC board contains four, 1 MSPS, input channel signals and an Open NAND Flash memory module with an analog to digital converter. The ADC, data bits, and control line signals from the board are sent to an Microsemi/Actel FPGA development kit for VHDL programming of the flash memory WRITE, READ, READ STATUS, ERASE, and RESET operation waveforms using Libero software. The debug board will be used for verification of the analog input signal and be able to communicate via serial interface with the module instrumentation. The scope of the new controller module was to find and develop an ONFI controller with the debug board layout designed and completed for manufacture. Successful flash memory operation waveform test routines were completed, simulated, and tested to work on the FPGA board. Through connection of the Flash/ADC board with the FPGA, it was found that the device specifications were not being meet with Vdd reaching half of its voltage. Further testing showed that it was the manufactured Flash/ADC board that contained a misalignment with the ONFI memory module traces. The errors proved to be too great to fix in the time limit set for the project.

  4. Carbon Footprint Reduction Instruments (United States)

    This page outlines the major differences between Renewable Energy Certificates (REC) and Project Offsets and what types of claims each instrument allows the organization to make in regards to environmental emissions claims.

  5. Fiber Optics Instrumentation Development (United States)

    Chan, Patrick Hon Man; Parker, Allen R., Jr.; Richards, W. Lance


    This is a general presentation of fiber optics instrumentation development work being conducted at NASA Dryden for the past 10 years and recent achievements in the field of fiber optics strain sensors.

  6. Ultrasound physics and instrumentation. (United States)

    Case, T D


    A knowledge of the principles of ultrasound physics and instrumentation allows the surgeon to maintain proper ultrasound techniques and obtain the best possible image. Furthermore, when these principles are understood, artifacts and pitfalls of imaging are avoided.

  7. Medical instruments in museums

    DEFF Research Database (Denmark)

    Söderqvist, Thomas; Arnold, Ken


    This essay proposes that our understanding of medical instruments might benefit from adding a more forthright concern with their immediate presence to the current historical focus on simply decoding their meanings and context. This approach is applied to the intriguingly tricky question of what a...... actually is meant by a "medical instrument." It is suggested that a pragmatic part of the answer might lie simply in reconsidering the holdings of medical museums, where the significance of the physical actuality of instruments comes readily to hand.......This essay proposes that our understanding of medical instruments might benefit from adding a more forthright concern with their immediate presence to the current historical focus on simply decoding their meanings and context. This approach is applied to the intriguingly tricky question of what...

  8. Options for Next Generation Digital Acquisition Systems

    CERN Document Server

    Boccardi, A


    Digital acquisition system designers have an always increasing number of options in terms of bus standards and digital signal processing hardware among which to choose. This allows for high flexibility but also opens the door to a proliferation of different architectures, potentially limiting the reusability and the design synergies among the various instrumentation groups. This contribution illustrates the design trends in some of the major institutes around the world with design examples including VME, PCI and TCA based modular systems using AMC and/or FMC mezzanines. Some examples of FPGA design practices aimed at increasing reusability of code will be mentioned together with some of the tools already available to designers to improve the information exchange and collaboration, like the Open Hardware Repository project.


    CERN Multimedia

    Gerry Bauer

    The CMS Storage Manager System The tail-end of the CMS Data Acquisition System is the Storage Manger (SM), which collects output from the HLT and stages the data at Cessy for transfer to its ultimate home in the Tier-0 center. A SM system has been used by CMS for several years with the steadily evolving software within the XDAQ framework, but until relatively recently, only with provisional hardware. The SM is well known to much of the collaboration through the ‘MiniDAQ’ system, which served as the central DAQ system in 2007, and lives on in 2008 for dedicated sub-detector commissioning. Since March of 2008 a first phase of the final hardware was commissioned and used in CMS Global Runs. The system originally planned for 2008 aimed at recording ~1MB events at a few hundred Hz. The building blocks to achieve this are based on Nexsan's SATABeast storage array - a device  housing up to 40 disks of 1TB each, and possessing two controllers each capable of almost 200 MB/sec throughput....

  10. Acquisition of Oocyte Polarity. (United States)

    Clapp, Mara; Marlow, Florence L


    Acquisition of oocyte polarity involves complex translocation and aggregation of intracellular organelles, RNAs, and proteins, along with strict posttranscriptional regulation. While much is still unknown regarding the formation of the animal-vegetal axis, an early marker of polarity, animal models have contributed to our understanding of these early processes controlling normal oogenesis and embryo development. In recent years, it has become clear that proteins with self-assembling properties are involved in assembling discrete subcellular compartments or domains underlying subcellular asymmetries in the early mitotic and meiotic cells of the female germline. These include asymmetries in duplication of the centrioles and formation of centrosomes and assembly of the organelle and RNA-rich Balbiani body, which plays a critical role in oocyte polarity. Notably, at specific stages of germline development, these transient structures in oocytes are temporally coincident and align with asymmetries in the position and arrangement of nuclear components, such as the nuclear pore and the chromosomal bouquet and the centrioles and cytoskeleton in the cytoplasm. Formation of these critical, transient structures and arrangements involves microtubule pathways, intrinsically disordered proteins (proteins with domains that tend to be fluid or lack a rigid ordered three-dimensional structure ranging from random coils, globular domains, to completely unstructured proteins), and translational repressors and activators. This review aims to examine recent literature and key players in oocyte polarity.

  11. Trigger and data acquisition

    CERN Multimedia

    CERN. Geneva; Gaspar, C


    Past LEP experiments generate data at 0.5 MByte/s from particle detectors with over a quarter of a million readout channels. The process of reading out the electronic channels, treating them, and storing the date produced by each collision for further analysis by the physicists is called "Data Acquisition". Not all beam crossings produce interesting physics "events", picking the interesting ones is the task of the "Trigger" system. In order to make sure that the data is collected in good conditions the experiment's operation has to be constantly verified. In all, at LEP experiments over 100 000 parameters were monitored, controlled, and synchronized by the "Monotoring and control" system. In the future, LHC experiments will produce as much data in a single day as a LEP detector did in a full year's running with a raw data rate of 10 - 100 MBytes/s and will have to cope with some 800 million proton-proton collisions a second of these collisions only one in 100 million million is interesting for new particle se...

  12. Modeling of Musical Instruments (United States)

    Bader, Rolf; Hansen, Uwe

    Signal processing techniques in acoustics address many concerns. Included are such things as wave propagation variables, amplitude considerations, spectral content, wavelength, and phase. Phase is primarily of concern when waves interact with each other, as well as with a medium, and the imposition of boundary conditions leads to normal mode vibrations. Such conditions are prevalent in all musical instruments, and thus relevant signal processing techniques are essential to both understanding and modeling the structure of musical instruments and the sound radiated.

  13. Future of radiological instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Lucas, A.C.


    Future trends in the development of radiation protection instrumentation can be expected to be closely related to current trends in political and social activity that drive legislation, rule-making, and standard practice, with assistance provided by trends in material and electronic technology. Wide-range performance will be emphasized to arm the daily worker with instruments that routinely log background rates and, at the same time, are prepared to measure accident rates. Separate and simultaneous accumulation of data from several sensors to ensure complete coverage of the radiation types will be common. Mathematical manipulation of data will provide for summary data logging and, in some cases, solutions to integral equations to provide corrections to experimental data. Instruments will become more reliable by way of self-checking and correction. Miniaturization and large-scale integration of measuring instruments will provide some instrumentation for the people at large. To be effective, the instruments will necessarily cover a wide range and be very reliable. The net result of these several trends will provide for a widespread understanding of radiation protection and an implementation of as low as reasonably achievable among large segments of the population.

  14. [The instrument for thermography]. (United States)

    Hamaguchi, Shinsuke


    Thermography is an imaging method using the instrument to detect infrared rays emitted from the body surface, and to plot them as a distribution diagram of the temperature information. Therefore, a thermographic instrument can be assumed to measure the skin temperature of the diseased region. Such an instrument is a useful device for noninvasive and objective assessment of various diseases. Examination using a thermographic instrument can assess the autonomic dysfunction by measuring the skin blood flow involved with the sympathetic innervation. Thermography is useful in assisting the determination of the therapeutic effect. However, autonomic dysfunction should be confirmed correctly with the assessment of thermatome that shows abnormal thermal distribution in the region of the disease. Thermography should make noticeable the difference between the body temperature of abnormal and normal sites, and show the alteration of temperature. Monitoring using thermography is useful to determine the effect of sympathetic nerve block. If a thermographic instrument is used, it is important that examiners should understand the function of the instrument, as well as its advantages and disadvantages.

  15. Feature Acquisition with Imbalanced Training Data (United States)

    Thompson, David R.; Wagstaff, Kiri L.; Majid, Walid A.; Jones, Dayton L.


    This work considers cost-sensitive feature acquisition that attempts to classify a candidate datapoint from incomplete information. In this task, an agent acquires features of the datapoint using one or more costly diagnostic tests, and eventually ascribes a classification label. A cost function describes both the penalties for feature acquisition, as well as misclassification errors. A common solution is a Cost Sensitive Decision Tree (CSDT), a branching sequence of tests with features acquired at interior decision points and class assignment at the leaves. CSDT's can incorporate a wide range of diagnostic tests and can reflect arbitrary cost structures. They are particularly useful for online applications due to their low computational overhead. In this innovation, CSDT's are applied to cost-sensitive feature acquisition where the goal is to recognize very rare or unique phenomena in real time. Example applications from this domain include four areas. In stream processing, one seeks unique events in a real time data stream that is too large to store. In fault protection, a system must adapt quickly to react to anticipated errors by triggering repair activities or follow- up diagnostics. With real-time sensor networks, one seeks to classify unique, new events as they occur. With observational sciences, a new generation of instrumentation seeks unique events through online analysis of large observational datasets. This work presents a solution based on transfer learning principles that permits principled CSDT learning while exploiting any prior knowledge of the designer to correct both between-class and withinclass imbalance. Training examples are adaptively reweighted based on a decomposition of the data attributes. The result is a new, nonparametric representation that matches the anticipated attribute distribution for the target events.

  16. Reducing the Cost of Laparoscopy: Reusable versus Disposable Laparoscopic Instruments

    Directory of Open Access Journals (Sweden)

    Dimitrios K. Manatakis


    Full Text Available Cost-effectiveness in health care management is critical. The situation in debt-stricken Greece is further aggravated by the financial crisis and constant National Health System expense cut-downs. In an effort to minimize the cost of laparoscopy, our department introduced reusable laparoscopic instruments in December 2011. The aim of this study was to assess potential cost reduction of laparoscopic operations in the field of general surgery. Hospital records, invoice lists, and operative notes between January 2012 and December 2013, were retrospectively reviewed and data were collected on laparoscopic procedures, instrument failures, and replacement needs. Initial acquisition cost of 5 basic instrument sets was €21,422. Over the following 24 months, they were used in 623 operations, with a total maintenance cost of €11,487. Based on an average retail price of €490 per set, projected cost with disposable instruments would amount to €305,270, creating savings of €272,361 over the two-year period under study. Despite the seemingly high purchase price, each set amortized its acquisition cost after only 9 procedures and instrument cost depreciated to less than €55 per case. Disposable instruments cost 9 times more than reusable ones, and their high price would almost equal the total hospital reimbursement by social security funds for many common laparoscopic procedures.

  17. Program Instrumentation and Trace Analysis (United States)

    Havelund, Klaus; Goldberg, Allen; Filman, Robert; Rosu, Grigore; Koga, Dennis (Technical Monitor)


    Several attempts have been made recently to apply techniques such as model checking and theorem proving to the analysis of programs. This shall be seen as a current trend to analyze real software systems instead of just their designs. This includes our own effort to develop a model checker for Java, the Java PathFinder 1, one of the very first of its kind in 1998. However, model checking cannot handle very large programs without some kind of abstraction of the program. This paper describes a complementary scalable technique to handle such large programs. Our interest is turned on the observation part of the equation: How much information can be extracted about a program from observing a single execution trace? It is our intention to develop a technology that can be applied automatically and to large full-size applications, with minimal modification to the code. We present a tool, Java PathExplorer (JPaX), for exploring execution traces of Java programs. The tool prioritizes scalability for completeness, and is directed towards detecting errors in programs, not to prove correctness. One core element in JPaX is an instrumentation package that allows to instrument Java byte code files to log various events when executed. The instrumentation is driven by a user provided script that specifies what information to log. Examples of instructions that such a script can contain are: 'report name and arguments of all called methods defined in class C, together with a timestamp'; 'report all updates to all variables'; and 'report all acquisitions and releases of locks'. In more complex instructions one can specify that certain expressions should be evaluated and even that certain code should be executed under various conditions. The instrumentation package can hence be seen as implementing Aspect Oriented Programming for Java in the sense that one can add functionality to a Java program without explicitly changing the code of the original program, but one rather writes an

  18. Data acquisition techniques using PC

    CERN Document Server

    Austerlitz, Howard


    Data Acquisition Techniques Using Personal Computers contains all the information required by a technical professional (engineer, scientist, technician) to implement a PC-based acquisition system. Including both basic tutorial information as well as some advanced topics, this work is suitable as a reference book for engineers or as a supplemental text for engineering students. It gives the reader enough understanding of the topics to implement a data acquisition system based on commercial products. A reader can alternatively learn how to custom build hardware or write his or her own software.

  19. Instrumentation and Controls Division annual progress report for period ending September 1, 1973

    Energy Technology Data Exchange (ETDEWEB)

    Sadowski, G.S. (comp.)


    Research progress is described under the following topics: (1) pulse counting and analysis; (2) support for the thermonuclear division ORMAK project; (3) miscellaneous electronics development; (4) detectors of ionizing particles and radiation; (5) radiation monitoring; (6) support for the Oak Ridge Electron Linear Accelerator; (7) automatic control and data acquisition; (8) process instrumentation and control; (9) reactor instrumentation and controls; (10) instrumentation for reactor division experiments and test loops; (11) maintenance and service; and (12) ecological science studies. (WHK)

  20. Instrumentation program for rock mechanics and spent fuel tests at the Nevada Test Site

    Energy Technology Data Exchange (ETDEWEB)

    Pratt, H.R.; Hustrulid, W.H.; Simonson, R.


    This report contains a discussion of an instrumentation and rock mechanics program recommended for consideration as part of the overall Lawrence Livermore nuclear waste storage program at NTS. It includes a discussion of (1) rationale for the heater tests, spent fuel facility evaluation, heated room tests, (2) recommended instrumentation types together with estimated delivery schedules, (3) recommended instrumentation layouts, (4) other proposed rock mechanics tests both laboratory and in situ, and (5) data acquisition and reduction requirements.

  1. International Instrumentation Symposium, 31st, San Diego, CA, May 6-9, 1985, Proceedings (United States)


    Consideration is given to techniques for measuring pressure, temperature, and solid mechanics, blast and shock instrumentation, flow measurements, measurement errors, and uncertainty analyses. Topics discussed include the applications of mini/microcomputers, data acquisition, processing, and analysis techniques and systems, and real-time control and display systems. Papers are presented on weighing instruments for space, special test facilities and data reduction procedures, flow applications, and wind tunnel instrumentation and control. Emphasis is given to the study of electrooptic and fiber optic instrumentation, NDT and acoustic emissions, software development for instrumentation, and science policies and the role of the government concerning scientific developments.

  2. Bootstrapping language acquisition. (United States)

    Abend, Omri; Kwiatkowski, Tom; Smith, Nathaniel J; Goldwater, Sharon; Steedman, Mark


    The semantic bootstrapping hypothesis proposes that children acquire their native language through exposure to sentences of the language paired with structured representations of their meaning, whose component substructures can be associated with words and syntactic structures used to express these concepts. The child's task is then to learn a language-specific grammar and lexicon based on (probably contextually ambiguous, possibly somewhat noisy) pairs of sentences and their meaning representations (logical forms). Starting from these assumptions, we develop a Bayesian probabilistic account of semantically bootstrapped first-language acquisition in the child, based on techniques from computational parsing and interpretation of unrestricted text. Our learner jointly models (a) word learning: the mapping between components of the given sentential meaning and lexical words (or phrases) of the language, and (b) syntax learning: the projection of lexical elements onto sentences by universal construction-free syntactic rules. Using an incremental learning algorithm, we apply the model to a dataset of real syntactically complex child-directed utterances and (pseudo) logical forms, the latter including contextually plausible but irrelevant distractors. Taking the Eve section of the CHILDES corpus as input, the model simulates several well-documented phenomena from the developmental literature. In particular, the model exhibits syntactic bootstrapping effects (in which previously learned constructions facilitate the learning of novel words), sudden jumps in learning without explicit parameter setting, acceleration of word-learning (the "vocabulary spurt"), an initial bias favoring the learning of nouns over verbs, and one-shot learning of words and their meanings. The learner thus demonstrates how statistical learning over structured representations can provide a unified account for these seemingly disparate phenomena. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Virtual Instrumentation and Virtual Environments

    NARCIS (Netherlands)

    Spoelder, H.J.W.


    Instrumentation, interaction and virtual environments provide a challenging triplet for the next generation of instrumentation and measurement tools. As such, they are the logical continuation of an increasingly important component within (virtual) instrumentation. Despite these changes, however,

  4. The application of a computer data acquisition system to a new high temperature tribometer (United States)

    Bonham, Charles D.; Dellacorte, Christopher


    The two data acquisition computer programs are described which were developed for a high temperature friction and wear test apparatus, a tribometer. The raw data produced by the tribometer and the methods used to sample that data are explained. In addition, the instrumentation and computer hardware and software are presented. Also shown is how computer data acquisition was applied to increase convenience and productivity on a high temperature tribometer.

  5. Critical parameters and performance tests for the evaluation of digital data acquisition hardware


    PAEPEN Jan; Gårdestig, Magnus; Reppenhagen Grim, Per; KEIGHTLEY John; Nilsson, Jonas; Peräjärvi, Kari; Tengblad, Olof; Toivonen, Harri


    Recent developments of digital data acquisition systems allow real-time pre-processing of detector signals at a high count rate. These so-called pulse processing digitizers are powerful and versatile instruments offering techniques which are important for nuclear security, critical infrastructure protection, nuclear physics and radiation metrology. Certain aspects of digital data acquisition affect the performance of the total system in a critical way and therefore require special attention. ...

  6. Accurate GPS Time-Linked data Acquisition System (ATLAS II) user's manual.

    Energy Technology Data Exchange (ETDEWEB)

    Jones, Perry L.; Zayas, Jose R.; Ortiz-Moyet, Juan (PrimeCore Systems Inc., Albuquerque, NM)


    The Accurate Time-Linked data Acquisition System (ATLAS II) is a small, lightweight, time-synchronized, robust data acquisition system that is capable of acquiring simultaneous long-term time-series data from both a wind turbine rotor and ground-based instrumentation. This document is a user's manual for the ATLAS II hardware and software. It describes the hardware and software components of ATLAS II, and explains how to install and execute the software.

  7. Instrumentation and Controls Division annual progress report for period ending September 1, 1974. Non-LMFBR program

    Energy Technology Data Exchange (ETDEWEB)

    Sadowski, G.S. (comp.)


    Research projects are summarized under the following categories: (1) basic electronics development; (2) engineering support for research facilities; (3) pulse counting and analysis; (4) radiation detection and monitoring; (5) instrument development; (6) automatic control and data acquisition; (7) process systems and instrumentation development; (8) reactor instrumentation and controls; (9) fuel reprocessing and shipping; (10) standards laboratory; (11) instrumentation for reactor division experiments and test loops; (12) maintenance and service; (13) ecological science studies; and (14) administration and training. (WHK)

  8. Schizophrenia and second language acquisition. (United States)

    Bersudsky, Yuly; Fine, Jonathan; Gorjaltsan, Igor; Chen, Osnat; Walters, Joel


    Language acquisition involves brain processes that can be affected by lesions or dysfunctions in several brain systems and second language acquisition may depend on different brain substrates than first language acquisition in childhood. A total of 16 Russian immigrants to Israel, 8 diagnosed schizophrenics and 8 healthy immigrants, were compared. The primary data for this study were collected via sociolinguistic interviews. The two groups use language and learn language in very much the same way. Only exophoric reference and blocking revealed meaningful differences between the schizophrenics and healthy counterparts. This does not mean of course that schizophrenia does not induce language abnormalities. Our study focuses on those aspects of language that are typically difficult to acquire in second language acquisition. Despite the cognitive compromises in schizophrenia and the manifest atypicalities in language of speakers with schizophrenia, the process of acquiring a second language seems relatively unaffected by schizophrenia.

  9. Platform attitude data acquisition system

    Digital Repository Service at National Institute of Oceanography (India)

    Afzulpurkar, S.

    A system for automatic acquisition of underwater platform attitude data has been designed, developed and tested in the laboratory. This is a micro controller based system interfacing dual axis inclinometer, high-resolution digital compass...

  10. Portable Data Acquisition System Project (United States)

    National Aeronautics and Space Administration — Armstrong researchers have developed a portable data acquisition system (PDAT) that can be easily transported and set up at remote locations to display and archive...

  11. Supervisory utilization as a support information instrument of the data base acquisition and availability by Intranet and Internet natural gas micro-cogeneration; Utilizacao de um supervisorio como ferramenta de suporte de informacoes na aquisicao e disponibilizacao dos dados via Intranet e Internet de um sistema de micro-cogeracao de energia

    Energy Technology Data Exchange (ETDEWEB)

    Camara, Paulo; Sousa, Walter [Centro de Tecnologias do Gas (CTGAS), Natal, RN (Brazil); Petch, Moacir; Diogenes, Pedro; Carrasco, Benjamim [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil)


    The globalization effects intensify the information of technology's usage, not only on the creation of new products and processes, as well, support to operation of new equipment. The Information Technology turns to being more penetrating in the companies' activities, making and changing paradigms and, consequently, in the way how information is conceived. In the partnership PETROBRAS, the Centro de Tecnologias do Gas - CTGAS and the group FOCKINK, was developed and has been launched in the brazilian market the first system of generation and micro-cogeneration by natural gas, activated by an engine diesel derivative by natural gas. The prototype is able to make 35 kW/55 kVA of electric energy, 7TR's (84.000 BTU's) of energy for refrigeration and has a capacity of warming 2200 l / h of water in the temperature of 25 deg C until 85 deg C. The equipment utilizes as a monitoring system a supervisor Elipse Scada, produced by Elipse, which is composed by acquisition and monitoring tools that turns possible the creation of screens with graphics to make easier the support, monitoring, activating and variable control, just like: pressure, temperature, electrical and mechanical. The supervisor keeps in touch with (02) two computers: the first, makes the communication with the supervisor system and the other is used to select the information to be able by web, through CTGAS home page. The access by home page of the information about the data on the co-generator will make easier the client's decision for the acquisition of the equipment. The main objective of this work is, through Information Technology is to present an application case of Elipse Scada Software in micro-cogeneration system installed at CTGAS to turn easier the obtainment of this information, change the relations into an integrate changing, expanding frontiers, creating by this way new challenges. (author)

  12. Acquisition of Scientific Equipment

    Energy Technology Data Exchange (ETDEWEB)

    Noland, Lynn [Director, Sponsored Programs


    Whitworth University constructed a 63,00 sq. ft. biology and chemistry building which opened in the Fall of 2011. This project provided for new state-of-the-art science instrumentation enabling Whitworth students to develop skills and knowledge that are directly transferable to practical applications thus enhancing Whitworth student's ability to compete and perform in the scientific workforce. Additionally, STEM faculty undertake outreach programs in the area schools, bringing students to our campus to engage in activities with our science students. The ability to work with insturmentation that is current helps to make science exciting for middle school and high school students and gets them thinking about careers in science. 14 items were purchased following the university's purchasing policy, that benefit instruction and research in the departments of biology, chemistry, and health sciences. They are: Cadaver Dissection Tables with Exhaust Chamber and accessories, Research Microscope with DF DIC, Phase and Fluorescence illumination with DP72 Camera, Microscope with Fluorescence, Microcomputer controlled ultracentrifuge, Ultracentrifuge rotor, Variable Temperature steam pressure sterilizer, Alliance APLC System, DNA Speedvac, Gel Cocumentation System, BioPac MP150, Glovebox personal workstation,Lyophilizer, Nano Drop 2000/2000c Spectrophotometer, C02 Incubator.

  13. Heat Flux Instrumentation Laboratory (HFIL) (United States)

    Federal Laboratory Consortium — Description: The Heat Flux Instrumentation Laboratory is used to develop advanced, flexible, thin film gauge instrumentation for the Air Force Research Laboratory....

  14. Biochemistry Instrumentation Core Technology Center (United States)

    Federal Laboratory Consortium — The UCLA-DOE Biochemistry Instrumentation Core Facility provides the UCLA biochemistry community with easy access to sophisticated instrumentation for a wide variety...

  15. Challenges in Mergers and Acquisitions


    Phyllis J. Rivera


    Since the advent of globalization and tough competitive market, there has been a drastic shift in the global business environment towards the acquisitions and mergers. The consolidation and acquisitions are undertaken for the purpose of increasing capabilities and gaining larger market share, but many high profile mergers become unsuccessful to meet the organizational objectives because of inadequate role of Human resources and the issues revolving in it (Love, 2000).The mergers and acquisiti...

  16. Prerequisites for acquisition of inheritance


    Večeřová, Marta


    Title: Prerequisites for Acquisition of Inheritance Keywords: deceased, inheritance, heir Type of paper: Thesis Author: Mgr. Daniela Bendová Supervisor: prof. JUDr. Jan Dvořák, CSc. Faculty of Law of Charles University Department of Civil Law The thesis addresses rudimentary prerequisites for acquisition of inheritance in the Czech Republic. These prerequisites include death of a person, that is necessary for application of inheritance rights, existence of inheritance, in particular ownership...

  17. Psychopharmacology of aggression in schizophrenia. (United States)

    Buckley, Peter; Citrome, Leslie; Nichita, Carmen; Vitacco, Michael


    The management of aggression in patients with schizophrenia is a complex and challenging clinical dilemma. It also is greatly influenced by prevailing societal and medicolegal considerations regarding the perceived associations between violence and mental illness. This article provides a succinct account of a complex area and offers evidence for available treatments to reduce the occurrence of violent behavior among patients with schizophrenia.

  18. The bioethics of cosmetic psychopharmacology

    African Journals Online (AJOL)


    genetics and surgery.2-7. What should a medical practitioner do when approached by a patient who states that they have read that SSRIs are a major advance in psychiatry, that they suffer from depression. (that does not meet criteria for depression or dysthymia) or shyness (that does not meet criteria for social anxiety disor-.

  19. The ethics of elective psychopharmacology (United States)

    Mohamed, Ahmed D.; Sahakian, Barbara J.


    Pharmacological cognitive enhancers (PCEs) are used to improve cognitive functions, such as attention, learning, memory and planning in patients with impairments in cognition resulting from traumatic brain injury (TBI) or from neuropsychiatric disorders such as Alzheimer's disease (AD), mild cognitive impairment, schizophrenia, and attention deficit hyperactivity disorder (ADHD). Moreover, PCEs have been shown to improve cognition in healthy volunteers with no psychiatric disorders. This article describes the rationale behind the need for their use in neuropsychiatric patients and illustrates how PCEs can ameliorate cognitive impairments, improve quality of life and wellbeing, and therefore reduce the economic burden associated with these disorders. We also describe evidence that PCEs are being used as cognitive enhancers by healthy people. Crucially, as the lifestyle use of these drugs becomes very popular in the healthy population, a final aim is to present an overview of the current and future neuroethical considerations of enhancing the healthy brain. As information regarding their actual use, benefits and harms in various healthy populations is currently lacking, we propose research that aims to obtain relevant empirical data, monitor the short- and long-term effectiveness and side-effects, and initiate accurate surveys to determine current patterns and quantity of usage of PCE drugs by healthy people. Furthermore, in order to instigate a dialogue between neuroethics and neuropsychopharmacology, we urge scientists to explore and communicate the social and ethical implications of their research to the public. Finally, we discuss and highlight other means of enhancing cognition in both patients and healthy adults, including education and physical exercise. PMID:21396152

  20. The ethics of elective psychopharmacology. (United States)

    Mohamed, Ahmed D; Sahakian, Barbara J


    Pharmacological cognitive enhancers (PCEs) are used to improve cognitive functions, such as attention, learning, memory and planning in patients with impairments in cognition resulting from traumatic brain injury (TBI) or from neuropsychiatric disorders such as Alzheimer's disease (AD), mild cognitive impairment, schizophrenia, and attention deficit hyperactivity disorder (ADHD). Moreover, PCEs have been shown to improve cognition in healthy volunteers with no psychiatric disorders. This article describes the rationale behind the need for their use in neuropsychiatric patients and illustrates how PCEs can ameliorate cognitive impairments, improve quality of life and wellbeing, and therefore reduce the economic burden associated with these disorders. We also describe evidence that PCEs are being used as cognitive enhancers by healthy people. Crucially, as the lifestyle use of these drugs becomes very popular in the healthy population, a final aim is to present an overview of the current and future neuroethical considerations of enhancing the healthy brain. As information regarding their actual use, benefits and harms in various healthy populations is currently lacking, we propose research that aims to obtain relevant empirical data, monitor the short- and long-term effectiveness and side-effects, and initiate accurate surveys to determine current patterns and quantity of usage of PCE drugs by healthy people. Furthermore, in order to instigate a dialogue between neuroethics and neuropsychopharmacology, we urge scientists to explore and communicate the social and ethical implications of their research to the public. Finally, we discuss and highlight other means of enhancing cognition in both patients and healthy adults, including education and physical exercise.

  1. [Psychopharmacology in aviation and astronautics]. (United States)

    Vasil'ev, P V; Glod, G D


    Flights aboard modern vehicles are associated with high nervous-emotional and physical stresses. This may induce depletion of reserve capabilities, development of fatigue and, consequently, reduction of work capacity of crewmembers. The paper discusses approaches and results of the use of drugs by pilots and cosmonauts in order to alleviate their fatigue and emotional stress. It gives indications and contraindications for the adminstration of stimulants and tranquilizers. On the basis of a comprehensive analysis of the literature data and their own findings, the authors draw the conclusion that the use of stimulants and anxiolytics may increase the level of reliability and performance of air- and spacecraft pilots during programmed and, particularly, contigent situations of the flight.

  2. The bioethics of cosmetic psychopharmacology

    African Journals Online (AJOL)


    Peter Kramer in his best-selling volume, “Listening to. Prozac”.1 This is a thoughtful piece on the possibility that ... shyness (that does not meet criteria for social anxiety disor- der) or from general dissatisfaction with ... dysthymia, social anxiety disorder, and personality disorders, it may be argued by extrapolation that these ...

  3. Psychopharmacologic treatment of pathologic aggression. (United States)

    Fava, M


    Several drugs are apparently effective in treating pathologic anger and aggression. Because many of the studies on aggressive populations allowed the use of concomitant medications, it is unclear whether the efficacy of each drug in a particular population is dependent on the presence of other medications, such as antipsychotic agents. Finally, one needs to be circumspect in inferring efficacy of a particular drug in aggressive patients with neuropsychiatric conditions other than the ones in which some efficacy has been established. Lithium appears to be an effective treatment of aggression among nonepileptic prison inmates, mentally retarded and handicapped patients, and among conduct-disordered children with explosive behavior. Certainly, lithium would be the treatment of choice in bipolar patients with excessive irritability and anger outbursts, and it has been shown to be effective in this population. Anticonvulsant medications are the treatment of choice for patients with outbursts of rage and abnormal EEG findings. The efficacy of these drugs in patients without a seizure disorder, however, remains to be established, with the exception perhaps of valproate and carbamazepine. In fact, dyphenylhydantoin did not appear to be effective in treating aggressive behavior in children with temper tantrums and was found to be effective in only a prison population. There is some evidence for the efficacy of carbamazepine and valproate in treating pathologic aggression in patients with dementia, organic brain syndrome, psychosis, and personality disorders. As Yudofsky et al point out in their review of the literature, although traditional antipsychotic drugs have been used widely to treat aggression, there is little evidence for their effectiveness in treating aggression beyond their sedative effect in agitated patients or their antiaggressive effect among patients whose aggression is related to active psychosis. Antipsychotic agents appear to be effective in treating psychotic aggressive patients, conduct-disordered children, and mentally retarded patients, with only modest effects in the management of pathologic aggression in patients with dementia. Furthermore, at least in one study, these drugs were found to be associated with increased aggressiveness in mentally retarded subjects. On the other hand, atypical antipsychotic agents (i.e., clozapine, risperidone, and olanzapine) may be more effective than traditional antipsychotic drugs in aggressive and violent populations, as they have shown efficacy in patients with dementia, brain injury, mental retardation, and personality disorders. Similarly, benzodiazepines can reduce agitation and irritability in elderly and demented populations, but they also can induce behavioral disinhibition. Therefore, one should be careful in using this class of drugs in patients with pathologic aggression. Beta-blockers appear to be effective in many different neuropsychiatric conditions. These drugs seem effective in reducing violent and assaultive behavior in patients with dementia, brain injury, schizophrenia, mental retardation, and organic brain syndrome. As pointed out by Campbell et al in their review of the literature, however, systematic research is lacking, and little is known about the efficacy and safety of beta-blockers in children and adolescents with pathologic aggression. Although widely used in the management of pathologic aggression, the use of this class of drugs has been limited partially by marked hypotension and bradycardia, which are side effects common at the higher doses. The usefulness of the antihypertensive drug clonidine in the treatment of pathologic aggression has not been assessed adequately, and only marginal benefits were observed with this drug in irritable autistic and conduct disorder children. Psychostimulants seem to be effective in reducing aggressiveness in brain-injured patients as well as in violent adolescents with oppositional or conduct disorders, particu

  4. Pediatric psychopharmacology: principles and practice

    National Research Council Canada - National Science Library

    Martin, Andrés; Scahill, Lawrence; Kratochvil, Christopher


    .... Neurobiology of Attention Regulation and its Disorders A.F.T. Arnsten and F.X. Castellanos 8. Neurobiology of Early Life Stress: Evolving Concepts Joan Kaufman and Natalie Weder 95 10. Neurobiology...

  5. Aethalometer™ Instrument Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Sedlacek, Arthur J. [Brookhaven National Lab. (BNL), Upton, NY (United States)


    The Aethalometer is an instrument that provides a real-time readout of the concentration of “Black” or “Elemental” carbon aerosol particles (BC or E) in an air stream (see Figure 1 and Figure 2). It is a self-contained instrument that measures the rate of change of optical transmission through a spot on a filter where aerosol is being continuously collected and uses the information to calculate the concentration of optically absorbing material in the sampled air stream. The instrument measures the transmitted light intensities through the “sensing” portion of the filter, on which the aerosol spot is being collected, and a “reference” portion of the filter as a check on the stability of the optical source. A mass flowmeter monitors the sample air flow rate. The data from these three measurements is used to determine the mean BC content of the air stream.

  6. Calibration of Geodetic Instruments

    Directory of Open Access Journals (Sweden)

    Marek Bajtala


    Full Text Available The problem of metrology and security systems of unification, correctness and standard reproducibilities belong to the preferred requirements of theory and technical practice in geodesy. Requirements on the control and verification of measured instruments and equipments increase and the importance and up-to-date of calibration get into the foreground. Calibration possibilities of length-scales (of electronic rangefinders and angle-scales (of horizontal circles of geodetic instruments. Calibration of electronic rangefinders on the linear comparative baseline in terrain. Primary standard of planar angle – optical traverse and its exploitation for calibration of the horizontal circles of theodolites. The calibration equipment of the Institute of Slovak Metrology in Bratislava. The Calibration process and results from the calibration of horizontal circles of selected geodetic instruments.


    Directory of Open Access Journals (Sweden)

    Cristian GHEORGHE


    Full Text Available The rules laid down by Romanian Capital Market Law and the regulations put in force for its implementation apply to issuers of financial instruments admitted to trading on the regulated market established in Romania. But the issuers remain companies incorporated under Company Law of 1990. Such dual regulations need increased attention in order to observe the legal status of the issuers/companies and financial instruments/shares. Romanian legislator has chosen to implement in Capital Market Law special rules regarding the administration of the issuers of financial instruments, not only rules regarding admitting and maintaining to a regulated market. Thus issuers are, in Romanian Law perspective, special company that should comply special rule regarding board of administration and general shareholders meeting.

  8. Virtual Sensor Test Instrumentation (United States)

    Wang, Roy


    Virtual Sensor Test Instrumentation is based on the concept of smart sensor technology for testing with intelligence needed to perform sell-diagnosis of health, and to participate in a hierarchy of health determination at sensor, process, and system levels. A virtual sensor test instrumentation consists of five elements: (1) a common sensor interface, (2) microprocessor, (3) wireless interface, (4) signal conditioning and ADC/DAC (analog-to-digital conversion/ digital-to-analog conversion), and (5) onboard EEPROM (electrically erasable programmable read-only memory) for metadata storage and executable software to create powerful, scalable, reconfigurable, and reliable embedded and distributed test instruments. In order to maximize the efficient data conversion through the smart sensor node, plug-and-play functionality is required to interface with traditional sensors to enhance their identity and capabilities for data processing and communications. Virtual sensor test instrumentation can be accessible wirelessly via a Network Capable Application Processor (NCAP) or a Smart Transducer Interlace Module (STIM) that may be managed under real-time rule engines for mission-critical applications. The transducer senses the physical quantity being measured and converts it into an electrical signal. The signal is fed to an A/D converter, and is ready for use by the processor to execute functional transformation based on the sensor characteristics stored in a Transducer Electronic Data Sheet (TEDS). Virtual sensor test instrumentation is built upon an open-system architecture with standardized protocol modules/stacks to interface with industry standards and commonly used software. One major benefit for deploying the virtual sensor test instrumentation is the ability, through a plug-and-play common interface, to convert raw sensor data in either analog or digital form, to an IEEE 1451 standard-based smart sensor, which has instructions to program sensors for a wide variety of

  9. Standard NIM Instrumentation System

    Energy Technology Data Exchange (ETDEWEB)

    Costrell, Louis [National Inst. of Standards and Technology (NIST), Gaithersburg, MD (United States); Lenkszus, Frank R. [Argonne National Lab. (ANL), Argonne, IL (United States); Rudnick, Stanley J. [Argonne National Lab. (ANL), Argonne, IL (United States); Davey, Eric [Atomic Energy of Canada (AECL), Limited, Chalk River, ON (Canada); Gould, John [Brookhaven National Lab. (BNL), Upton, NY (United States); Rankowitz, Seymour [Brookhaven National Lab. (BNL), Upton, NY (United States); Sims, William P. [Brookhaven National Lab. (BNL), Upton, NY (United States); Whitney, R. Roy [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States). Continuous Electron Beam Accelerator Facility (CEBAF); Dobinson, Robert W. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Verweij, Henk [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Latner, Norman [Environmental Measurements Lab., New York, NY (United States); Negro, Vincent C. [Environmental Measurements Lab., New York, NY (United States); Barsotti, Edward J. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Droege, Thomas E. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Kerns, Cordon [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Turner, Kathleen J. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Downing, Robert W. [Univ. of Illinois, Urbana, IL (United States); Kirsten, Frederick A. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Larsh, A. E. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Loken, Stewart C. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Mack, Dick A. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Wagner, Lee J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Lucena, Robert C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); O' Brien, Dennis W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Gjovig, Allan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Naivar, Frank [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Nelson, Ronald O. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); White, D. Hywell [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Akerlof, Carl [Univ. of Michigan, Ann Arbor, MI (United States); Stilwell, Donald E. [National Aeronautics and Space Administration, Washington, DC (United States); Trainor, James H. [National Aeronautics and Space Administration, Washington, DC (United States); Gobbi, Bruno [Northwestern Univ., Evanston, IL (United States); Biggerstaff, John A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hill, Nat W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Schulze, Gerald K. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Gustavson, David B. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Horelick, Dale [SLAC National Accelerator Lab., Menlo Park, CA (United States); Kunz, Paul F. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Paffrath, Leo [SLAC National Accelerator Lab., Menlo Park, CA (United States); Walz, Helmut V. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Dawson, W. Kenneth [TRIUMF, Vancouver, BC (Canada); Cresswell, John [TRIUMF, Vancouver, BC (Canada); Dhawan, Satish [Yale Univ., New Haven, CT (United States); Gingell, Charles E. L. [Yale Univ., New Haven, CT (United States)


    NIM is a standard modular instrumentation system that is in wide use throughout the world. As the NIM system developed and accommodations were made to a dynamic instrumentation field and a rapidly advancing technology, additions, revisions and clarifications were made. These were incorporated into the standard in the form of addenda and errata. This standard is a revision of the NIM document, AEC Report TID-20893 (Rev 4) dated July 1974. It includes all the addenda and errata items that were previously issued as well as numerous additional items to make the standard current with modern technology and manufacturing practice.

  10. Instrumentation Cables Test Plan

    Energy Technology Data Exchange (ETDEWEB)

    Muna, Alice Baca [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); LaFleur, Chris Bensdotter [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)


    A fire at a nuclear power plant (NPP) has the potential to damage structures, systems, and components important to safety, if not promptly detected and suppressed. At Browns Ferry Nuclear Power Plant on March 22, 1975, a fire in the reactor building damaged electrical power and control systems. Damage to instrumentation cables impeded the function of both normal and standby reactor coolant systems, and degraded the operators’ plant monitoring capability. This event resulted in additional NRC involvement with utilities to ensure that NPPs are properly protected from fire as intended by the NRC principle design criteria (i.e., general design criteria 3, Fire Protection). Current guidance and methods for both deterministic and performance based approaches typically make conservative (bounding) assumptions regarding the fire-induced failure modes of instrumentation cables and those failure modes effects on component and system response. Numerous fire testing programs have been conducted in the past to evaluate the failure modes and effects of electrical cables exposed to severe thermal conditions. However, that testing has primarily focused on control circuits with only a limited number of tests performed on instrumentation circuits. In 2001, the Nuclear Energy Institute (NEI) and the Electric Power Research Institute (EPRI) conducted a series of cable fire tests designed to address specific aspects of the cable failure and circuit fault issues of concern1. The NRC was invited to observe and participate in that program. The NRC sponsored Sandia National Laboratories to support this participation, whom among other things, added a 4-20 mA instrumentation circuit and instrumentation cabling to six of the tests. Although limited, one insight drawn from those instrumentation circuits tests was that the failure characteristics appeared to depend on the cable insulation material. The results showed that for thermoset insulated cables, the instrument reading tended to drift

  11. Spectroelectrochemical Instrument Measures TOC (United States)

    Kounaves, Sam


    A spectroelectrochemical instrument has been developed for measuring the total organic carbon (TOC) content of an aqueous solution. Measurements of TOC are frequently performed in environmental, clinical, and industrial settings. Until now, techniques for performing such measurements have included, various ly, the use of hazardous reagents, ultraviolet light, or ovens, to promote reactions in which the carbon contents are oxidized. The instrument now being developed is intended to be a safer, more economical means of oxidizing organic carbon and determining the TOC levels of aqueous solutions and for providing a low power/mass unit for use in planetary missions.

  12. Standard NIM instrumentation system

    CERN Document Server


    NIM is a standard modular instrumentation system that is in wide use throughout the world. As the NIM system developed and accommodations were made to a dynamic instrumentation field and a rapidly advancing technology, additions, revisions and clarifications were made. These were incorporated into the standard in the form of addenda and errata. This standard is a revision of the NIM document, AEC Report TID- 20893 (Rev 4) dated July 1974. It includes all the addenda and errata items that were previously issued as well as numerous additional items to make the standard current with modern technology and manufacturing practice.

  13. A Labview based FPGA data acquisition with integrated stage and beam transport control

    Energy Technology Data Exchange (ETDEWEB)

    Laird, J.S., E-mail: [CSIRO, Earth Science and Resource Engineering, Clayton, Victoria (Australia); Centre of Excellence in Ore Deposits (CODES), University of Tasmania, Hobart, Tasmania (Australia); School of Physics, University of Melbourne, Parkville 3010, Victoria (Australia); Szymanski, R. [School of Physics, University of Melbourne, Parkville 3010, Victoria (Australia); Ryan, C.G. [CSIRO, Earth Science and Resource Engineering, Clayton, Victoria (Australia); Centre of Excellence in Ore Deposits (CODES), University of Tasmania, Hobart, Tasmania (Australia); School of Physics, University of Melbourne, Parkville 3010, Victoria (Australia); Gonzalez-Alvarez, I. [CSIRO, Earth Science and Resource Engineering, Kensington, Western Australia (Australia)


    We report on a new FPGA based data acquisition system developed for the CSIRO Nuclear Microprobe (NMP) which is tightly integrated with both target positioning and beam transport. The data acquisition system called MicrodaQ is based on National Instruments Labview FPGA and numerous instrumentation modules spread over several PC’s. Beam transport uses a feedback control loop to optimise current on target for long unmanned experiments. These upgrades are discussed in detail and an example of the systems use for μ-Particle Induced X-ray Emission (PIXE) analysis on a Doriri apatite is briefly described.


    Directory of Open Access Journals (Sweden)

    Vancea Mariana


    Full Text Available This paper analyses the mergers and acquisitions waves that took place in history, emphasizing the generating factors of each wave of operations, as well as the particularities specific to each period. Systematically, these growth and development instruments have become very attractive for the firms in the entire Europe and, in the present, the phenomenon of mergers and acquisitions represents a reality having a major impact on national economies and also on the world economy. This research is based on a systematic, logical and comparative analysis of scientific literature and statistical data regarding mergers and acquisitions.

  15. Instrumentation for the Characterization of Inflatable Structures (United States)

    Swanson, Gregory T.; Cassell, Alan M.; Johnson, R. Keith


    Current entry, descent, and landing technologies are not practical for heavy payloads due to mass and volume constraints dictated by limitations imposed by launch vehicle fairings. Therefore, new technologies are now being explored to provide a mass- and volume-efficient solution for heavy payload capabilities, including Inflatable Aerodynamic Decelerators (IAD) [1]. Consideration of IADs for space applications has prompted the development of instrumentation systems for integration with flexible structures to characterize system response to flight-like environment testing. This development opportunity faces many challenges specific to inflatable structures in extreme environments, including but not limited to physical flexibility, packaging, temperature, structural integration and data acquisition [2]. In the spring of 2012, two large scale Hypersonic Inflatable Aerodynamic Decelerators (HIAD) will be tested in the National Full-Scale Aerodynamics Complex s 40 by 80 wind tunnel at NASA Ames Research Center. The test series will characterize the performance of a 3.0 m and 6.0 m HIAD at various angles of attack and levels of inflation during flight-like loading. To analyze the performance of these inflatable test articles as they undergo aerodynamic loading, many instrumentation systems have been researched and developed. These systems will utilize new experimental sensing systems developed by the HIAD ground test campaign instrumentation team, in addition to traditional wind tunnel sensing techniques in an effort to improve test article characterization and model validation. During the 2012 test series the instrumentation systems will target inflatable aeroshell static and dynamic deformation, structural strap loading, surface pressure distribution, localized skin deflection, and torus inflation pressure. This paper will offer an overview of inflatable structure instrumentation, and provide detail into the design and implementation of the sensors systems that will

  16. Social Networking of Instrumentation - a Case Study in Telematics

    Directory of Open Access Journals (Sweden)

    ROBU, D.


    Full Text Available The research work contributes to the design and implementation of the communication part for integrating remote instruments and drives via social networks (SN into instrumentation communities. It is used the virtual instrumentation (VI to manage objects that tweet on popular SN platforms applying the concept of the Internet of Things (IoT. Local and remote resource aggregation is based on National Instruments (NI data acquisition and distribution hardware in a NI software environment. NI LabVIEW-for-Twitter solutions (starting with simple authentication are extended, integrated with various third party services and validated in a complete remote monitoring proof-of-concept workbench with a closed loop for alarming-compensation. Solutions are extendible to Machine-to-Machine communication (M2M IoT scenarios for telematics, monitoring or control, and can be connected to intelligent systems based on powerful servers for cloud computing.

  17. Specification for Instrumentation

    DEFF Research Database (Denmark)

    Margheritini, Lucia; Kofoed, Jens Peter

    This paper is intended to give an overview on instrumentation for monitoring the efficiency of the Converter and the performance of the device. Real-time control of plant and data monitoring and storage are the main objectives of the control system....

  18. The ozone monitoring instrument

    NARCIS (Netherlands)

    Levelt, P.F.; Oord, G.H.J. van den; Dobber, M.R.; Mälkki, A.; Visser, H.; Vries, J. de; Stammes, P.; Lundell, J.O.V.; Saari, H.


    The Ozone Monitoring Instrument (OMI) flies on the National Aeronautics and Space Adminsitration's Earth Observing System Aura satellite launched in July 2004. OMI is a ultraviolet/visible (UV/VIS) nadir solar backscatter spectrometer, which provides nearly global coverage in one day with a spatial

  19. Integrating Nephelometer Instrument Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Uin, J. [Brookhaven National Lab. (BNL), Upton, NY (United States)


    The Integrating Nephelometer (Figure 1) is an instrument that measures aerosol light scattering. It measures aerosol optical scattering properties by detecting (with a wide angular integration – from 7 to 170°) the light scattered by the aerosol and subtracting the light scattered by the carrier gas, the instrument walls and the background noise in the detector (zeroing). Zeroing is typically performed for 5 minutes every day at midnight UTC. The scattered light is split into red (700 nm), green (550 nm), and blue (450 nm) wavelengths and captured by three photomultiplier tubes. The instrument can measure total scatter as well as backscatter only (from 90 to 170°) (Heintzenberg and Charlson 1996; Anderson et al. 1996; Anderson and Ogren 1998; TSI 3563 2015) At ARM (Atmospheric Radiation Measurement), two identical Nephelometers are usually run in series with a sample relative humidity (RH) conditioner between them. This is possible because Nephelometer sampling is non-destructive and the sample can be passed on to another instrument. The sample RH conditioner scans through multiple RH values in cycles, treating the sample. This kind of setup allows to study how aerosol particles’ light scattering properties are affected by humidification (Anderson et al. 1996). For historical reasons, the two Nephelometers in this setup are labeled “wet” and “dry”, with the “dry” Nephelometer usually being the one before the conditioner and sampling ambient air (the names are switched for the MAOS measurement site due to the high RH of the ambient air).

  20. Measurement and Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Kirkham, Harold


    This is a chapter for a book called the Standard Handbook for Electrical Engineering. Though it is not obvious from the title, the book deals mainly with power engineering. The first chapter (not mine) is about the fundamental quantities used in measurement. This chapter is about the process and the instrumentation.

  1. Neutron instrumentation for biology

    Energy Technology Data Exchange (ETDEWEB)

    Mason, S.A. [Institut Laue-Langevin, Grenoble (France)


    In the October 1994 round of proposals at the ILL, the external biology review sub- committee was asked to allocate neutron beam time to a wide range of experiments, on almost half the total number of scheduled neutron instruments: on 3 diffractometers, on 3 small angle scattering instruments, and on some 6 inelastic scattering spectrometers. In the 3.5 years since the temporary reactor shutdown, the ILL`s management structure has been optimized, budgets and staff have been trimmed, the ILL reactor has been re-built, and many of the instruments up-graded, many powerful (mainly Unix) workstations have been introduced, and the neighboring European Synchrotron Radiation Facility has established itself as the leading synchrotron radiation source and has started its official user program. The ILL reactor remains the world`s most intense dedicated neutron source. In this challenging context, it is of interest to review briefly the park of ILL instruments used to study the structure and energetics of small and large biological systems. A brief summary will be made of each class of experiments actually proposed in the latest ILL proposal round.

  2. Economic Policy Instruments

    DEFF Research Database (Denmark)

    Klemmensen, Børge


    Økonomiske instrumenter begrundes med behovet for politiske indgreb, der muliggør internaliseringen af omkostningerne ved de miljøpåvirkninger, produktion and levevis afstedkommer, således at hensyntagen til miljøet bliver en del af virksomheders og husholdningers omkostninger og dermed en tilsky...

  3. Virtual reality musical instruments

    DEFF Research Database (Denmark)

    Serafin, Stefania; Erkut, Cumhur; Kojs, Juraj


    The rapid development and availability of low cost technologies has created a wide interest in virtual reality (VR), but how to design and evaluate multisensory interactions in VR remains as a challenge. In this paper, we focus on virtual reality musical instruments, present an overview of our...

  4. Deep Impact instrument calibration (United States)

    Klaasen, K.; A'Hearn, M. F.; Baca, M.; Delamere, A.; Desnoyer, M.; Farnham, T.; Groussin, O.; Hampton, D.; Ipatov, S.; Li, J.-Y.; Lisse, C.; Mastrodemos, N.; McLaughlin, S.; Sunshine, J.; Thomas, P.; Wellnitz, D.


    Calibration of NASA's Deep Impact spacecraft instruments allows reliable scientific interpretation of the images and spectra returned from comet Tempel 1. Calibrations of the four onboard remote sensing imaging instruments have been performed in the areas of geometric calibration, spatial resolution, spectral resolution, and radiometric response. Error sources such as noise (random, coherent, encoding, data compression), detector readout artifacts, scattered light, and radiation interactions have been quantified. The point spread functions (PSFs) of the medium resolution instrument and its twin impactor targeting sensor are near the theoretical minimum [~1.7 pixels full width at half maximum (FWHM)]. However, the high resolution instrument camera was found to be out of focus with a PSF FWHM of ~9 pixels. The charge coupled device (CCD) read noise is ~1 DN. Electrical cross-talk between the CCD detector quadrants is correctable to <2 DN. The IR spectrometer response nonlinearity is correctable to ~1%. Spectrometer read noise is ~2 DN. The variation in zero-exposure signal level with time and spectrometer temperature is not fully characterized; currently corrections are good to ~10 DN at best. Wavelength mapping onto the detector is known within 1 pixel; spectral lines have a FWHM of ~2 pixels. About 1% of the IR detector pixels behave badly and remain uncalibrated. The spectrometer exhibits a faint ghost image from reflection off a beamsplitter. Instrument absolute radiometric calibration accuracies were determined generally to <10% using star imaging. Flat-field calibration reduces pixel-to-pixel response differences to ~0.5% for the cameras and <2% for the spectrometer. A standard calibration image processing pipeline is used to produce archival image files for analysis by researchers.

  5. Atmospheric Composition Instrumentation. (United States)


    9fI urpAt .~~~ — 7. A THOR(a) 9. CON I RACT OR GRANT HUM BER(.) ! ~~~~~~~~ /otis 7 ~~ ~~F 1962~~~ 4~~~~~~ 1 H 9. FoRMING ORGANIZATION NAN NO...objective of the Upper Atmosphere Re- search Program is the acquisition of 1- nowledge of the ohysica] and chemica ) properties and phenomena of the vitally

  6. Operational Test Instrumentation Guide. (United States)


    506U 2 IRIG time code generator Systron Donner model 8526 2 Camera, video Edo Western model 1411 6 Time date generators lET model VTG 302 10 Time date...used in tests. They are capable of manual or automatic acquisition and tracking of targets in flight or orbit by target echo or beacon. Range is from...4500 visible Camera, mini 4 projects as " Edo Western 1800 Recorder/Repro- required 3 ducer 12 Sony V03800/2000/2860 monitor 10 9/14/17" Conrac SNA/RQB

  7. The Science of String Instruments

    CERN Document Server

    Rossing, Thomas D


    Many performing musicians, as well as instrument builders, are coming to realize the importance of understanding the science of musical instruments. This book explains how string instruments produce sound. It presents basic ideas in simple language, and it also translates some more sophisticated ideas in non-technical language. It should be of interest to performers, researchers, and instrument makers alike.

  8. 48 CFR 434.004 - Acquisition strategy. (United States)


    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Acquisition strategy. 434... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION General 434.004 Acquisition strategy. (a) The program... Systems Executive, a written charter outlining the authority, responsibility, accountability, and budget...

  9. A Virtual Instrument System for Determining Sugar Degree of Honey

    Directory of Open Access Journals (Sweden)

    Qijun Wu


    Full Text Available This study established a LabVIEW-based virtual instrument system to measure optical activity through the communication of conventional optical instrument with computer via RS232 port. This system realized the functions for automatic acquisition, real-time display, data processing, results playback, and so forth. Therefore, it improved accuracy of the measurement results by avoiding the artificial operation, cumbersome data processing, and the artificial error in optical activity measurement. The system was applied to the analysis of the batch inspection on the sugar degree of honey. The results obtained were satisfying. Moreover, it showed advantages such as friendly man-machine dialogue, simple operation, and easily expanded functions.

  10. netherland hydrological modeling instrument (United States)

    Hoogewoud, J. C.; de Lange, W. J.; Veldhuizen, A.; Prinsen, G.


    Netherlands Hydrological Modeling Instrument A decision support system for water basin management. J.C. Hoogewoud , W.J. de Lange ,A. Veldhuizen , G. Prinsen , The Netherlands Hydrological modeling Instrument (NHI) is the center point of a framework of models, to coherently model the hydrological system and the multitude of functions it supports. Dutch hydrological institutes Deltares, Alterra, Netherlands Environmental Assessment Agency, RWS Waterdienst, STOWA and Vewin are cooperating in enhancing the NHI for adequate decision support. The instrument is used by three different ministries involved in national water policy matters, for instance the WFD, drought management, manure policy and climate change issues. The basis of the modeling instrument is a state-of-the-art on-line coupling of the groundwater system (MODFLOW), the unsaturated zone (metaSWAP) and the surface water system (MOZART-DM). It brings together hydro(geo)logical processes from the column to the basin scale, ranging from 250x250m plots to the river Rhine and includes salt water flow. The NHI is validated with an eight year run (1998-2006) with dry and wet periods. For this run different parts of the hydrology have been compared with measurements. For instance, water demands in dry periods (e.g. for irrigation), discharges at outlets, groundwater levels and evaporation. A validation alone is not enough to get support from stakeholders. Involvement from stakeholders in the modeling process is needed. There fore to gain sufficient support and trust in the instrument on different (policy) levels a couple of actions have been taken: 1. a transparent evaluation of modeling-results has been set up 2. an extensive program is running to cooperate with regional waterboards and suppliers of drinking water in improving the NHI 3. sharing (hydrological) data via newly setup Modeling Database for local and national models 4. Enhancing the NHI with "local" information. The NHI is and has been used for many

  11. Developments in analytical instrumentation (United States)

    Petrie, G.

    The situation regarding photogrammetric instrumentation has changed quite dramatically over the last 2 or 3 years with the withdrawal of most analogue stereo-plotting machines from the market place and their replacement by analytically based instrumentation. While there have been few new developments in the field of comparators, there has been an explosive development in the area of small, relatively inexpensive analytical stereo-plotters based on the use of microcomputers. In particular, a number of new instruments have been introduced by manufacturers who mostly have not been associated previously with photogrammetry. Several innovative concepts have been introduced in these small but capable instruments, many of which are aimed at specialised applications, e.g. in close-range photogrammetry (using small-format cameras); for thematic mapping (by organisations engaged in environmental monitoring or resources exploitation); for map revision, etc. Another innovative and possibly significant development has been the production of conversion kits to convert suitable analogue stereo-plotting machines such as the Topocart, PG-2 and B-8 into fully fledged analytical plotters. The larger and more sophisticated analytical stereo-plotters are mostly being produced by the traditional mainstream photogrammetric systems suppliers with several new instruments and developments being introduced at the top end of the market. These include the use of enlarged photo stages to handle images up to 25 × 50 cm format; the complete integration of graphics workstations into the analytical plotter design; the introduction of graphics superimposition and stereo-superimposition; the addition of correlators for the automatic measurement of height, etc. The software associated with this new analytical instrumentation is now undergoing extensive re-development with the need to supply photogrammetric data as input to the more sophisticated G.I.S. systems now being installed by clients, instead

  12. 75 FR 77721 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-47; Introduction (United States)


    ... ADMINISTRATION 48 CFR Chapter 1 Federal Acquisition Regulation; Federal Acquisition Circular 2005-47... Council and the Defense Acquisition Regulations Council (Councils) in this Federal Acquisition Circular... interagency acquisitions, not just those made under the Economy Act authority. A new subsection 17.502-1 is...

  13. Computational models of syntactic acquisition. (United States)

    Yang, Charles


    The computational approach to syntactic acquisition can be fruitfully pursued by integrating results and perspectives from computer science, linguistics, and developmental psychology. In this article, we first review some key results in computational learning theory and their implications for language acquisition. We then turn to examine specific learning models, some of which exploit distributional information in the input while others rely on a constrained space of hypotheses, yet both approaches share a common set of characteristics to overcome the learning problem. We conclude with a discussion of how computational models connects with the empirical study of child grammar, making the case for computationally tractable, psychologically plausible and developmentally realistic models of acquisition. WIREs Cogn Sci 2012, 3:205-213. doi: 10.1002/wcs.1154 For further resources related to this article, please visit the WIREs website. Copyright © 2011 John Wiley & Sons, Ltd.

  14. Virtual Reality Musical Instruments

    DEFF Research Database (Denmark)

    Serafin, Stefania; Erkut, Cumhur; Kojs, Juraj


    The rapid development and availability of low-cost technologies have created a wide interest in virtual reality. In the field of computer music, the term “virtual musical instruments” has been used for a long time to describe software simulations, extensions of existing musical instruments......, and ways to control them with new interfaces for musical expression. Virtual reality musical instruments (VRMIs) that include a simulated visual component delivered via a head-mounted display or other forms of immersive visualization have not yet received much attention. In this article, we present a field...... overview of VRMIs from the viewpoint of the performer. We propose nine design guidelines, describe evaluation methods, analyze case studies, and consider future challenges....

  15. Pesticide reducing instruments

    DEFF Research Database (Denmark)

    Jacobsen, Lars-Bo; Jensen, Jørgen Dejgård; Andersen, Martin


    -mentioned models and tools. All three scenarios are constructed such that they result in the same welfare implication (measured by national consumption in the CGE model). The scenarios are: 1) pesticide taxes resulting in a 25 percent overall reduction; 2) use of unsprayed field margins, resulting in the same...... welfare loss as in scenario 1; and finally 3) increased conversion to organic farming also resulting in the same welfare loss as in scenario 1. Biological and geological results from the first part of our analysis suggest that the use of unsprayed field margins is the most cost-effective instrument...... for improving bio-diversity and securing drinking water. That is, combining economic modeling with physical biological modeling and geological evaluation allows us to select unsprayed field margins as the most effective instrument. Sensitivity analysis conducted on bio-diversity suggest that this result...

  16. Social Responsibility Instruments

    Directory of Open Access Journals (Sweden)

    Katarzyna Mizera


    Full Text Available Responsible business notion is more and more present in Polish economy, however the results of the research carried out in Polish business still shows a low level of CRS idea knowledge, especially in small and medium companies. Although responsible business notion is generally known, its details, ways of preparing strategy, instruments and what is more its benefits are still narrowly spread. Many business people face the lack of knowledge and information, which on one hand make it easier to spread and deepen wrong stereotypes connected with this notion and on the other hand make business people unwilling to implement CRS in their companies. The subjects of this article are examples of instruments which are responsible for realization of social responsibility strategy.

  17. Axis instrumentation: surgical results

    Directory of Open Access Journals (Sweden)

    Andrei F. Joaquim


    Full Text Available OBJECTIVE: Evaluate the surgical results of axis screw instrumentation. METHODS: Retrospective evaluation of the clinical and radiological data of patients submitted to axis fixation using screws. RESULTS: Seventeen patients were surgically treated. The mean age was 41.8 years (range: 12-73. Spinal cord trauma was the most common cause of instability (8 patients - 47%. Bilateral axis fixation was performed in all cases, except one, with laminar screw (total of 33 axis screws. Seven patients (41.1% underwent bilateral pars screws; laminar screws were used in six cases and pedicular screws were used in two. In two cases, we performed a hybrid construction (laminar + pars and pedicle + pars. There was no neurological worsening or death, nor complications directly related to use axis screws. CONCLUSION: Axis instrumentation was effective and safe, regardless of the technique used for stabilization. Based on our learnt experience, we proposed an algorithm to choose the best technique for axis screw fixation.

  18. Spectroradiometric Instruments And Applications (United States)

    Walker, Richard A.; Miller, Kenneth A.; Bulpitt, Thomas H.


    This paper discusses spectroradiometric instruments and applications. Multiple-detector spectroradiometers and single-detector scanning spectroradiometers are described, with particular emphasis on current state-of-the-art integrated systems. Applications discussed include: color measurement (colorimetry); photometry and colorimetry of cathode-ray-tubes , light-emitting-diodes and other displays; photometry and colorimetry of light sources and flash lamps; and colorimetry of reflective and transmissive materials. Future trends are also discussed.

  19. Guide to Instrumentation Literature (United States)


    pp. 2622. L. K. Spink, Princirles and practice of flow meter engineering., Iie Foxboro Coo, Foxboro$ Mass., Ed. 7# 1950. 1418 pp. 2623. Reid F...ring. 1952. 269 pp. Vol., 2 - Method- for associating mathematical solutions with common forms, 1953. 827 pp. Vol. 3 - Applications of the instrument...weights, and Volumetric glassware. -13.1 - 2.9. Periodicals P1100. Standards; Metrology; Testing, General (Cont.) P1127. Revista chilena do

  20. Instrumentation: endoscopes and equipment. (United States)

    Gaab, Michael R


    The technology and instrumentation for neuroendoscopy are described: endoscopes (principles, designs, applications), light sources, instruments, accessories, holders, and navigation. Procedures for cleaning, sterilizing, and storing are included. The description is based on the author's own technical development and neuroendoscopic experience, published technology and devices, and publications on endoscopic surgery. The main work horses in neuroendoscopy are rigid glass rod endoscopes (Hopkins optics) due to the optical quality, which allows full high-definition video imaging, different angles of view, and autoclavability, which is especially important in neuroendoscopy due to the risk of Creutzfeldt-Jakob disease infection. Applications are endoscopy assistance to microsurgery, stand-alone endoscopy controlled approaches such as transnasal skull base, ventriculoscopy, and cystoscopy in the cranium. Rigid glass rod optics are also applicable in spinal endoscopy and peripheral nerve decompression using special tubes and cannulas. Rigid minifiberoptics with less resolution may be used in less complex procedures (ventriculoscopy, cystoscopy, endoscopy assistance with pen-designs) and have the advantages of smaller diameters and disposable designs. Flexible fiberoptics are usually used in combination with rigid scopes and can be steered, e.g. through the ventricles, in spinal procedures for indications including syringomyelia and multicystic hydrocephalus. Upcoming flexible chip endoscopes ("chip-in-the-tip") may replace flexible fiberoptics in the future, offering higher resolution and cold LED-illumination, and may provide for stereoscopic neuroendoscopy. Various instruments (mechanical, coagulation, laser guides, ultrasonic aspirators) and holders are available. Certified methods for cleaning and sterilization, with special requirements in neuroapplications, are important. Neuroendoscopic instrumentation is now an established technique in neurosurgical practice and

  1. Instrumentation and diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Nakaishi, C.V.; Bedick, R.C.


    This Technology Status Report describes research and accomplishments for the Instrumentation and Diagnostics (I D) Projects within the Advanced Research and Technology Development (AR TD) Program of the United States Department of Energy (DOE) Office of Fossil Energy (FE). Process understanding and control can be improved through the development of advanced instrumentation and diagnostics. The thrust of the I D Projects is to further develop existing measurement and control techniques for application to advanced coal-based technologies. Project highlights are: an inductively coupled plasma (ICP) instrument has been developed to analyze trace elements in gasification and combustion process streams. An in situ two-color Mie scattering technique with LSS can simultaneously measure the size, velocity, and elemental composition of coal particles during combustion. A high-temperature, fluorescence thermometry technique has accurately measured gas temperatures during field testing in combustion and gasification environments. Expert systems have been developed to improve the control of advanced coal-based processes. Capacitance flowmeters were developed to determine the mass flowrate, solid volume fraction, and particle velocities of coal slurries. 32 refs., 9 figs.

  2. High Quality Acquisition of Surface Electromyography - Conditioning Circuit Design (United States)

    Shobaki, Mohammed M.; Malik, Noreha Abdul; Khan, Sheroz; Nurashikin, Anis; Haider, Samnan; Larbani, Sofiane; Arshad, Atika; Tasnim, Rumana


    The acquisition of Surface Electromyography (SEMG) signals is used for many applications including the diagnosis of neuromuscular diseases, and prosthesis control. The diagnostic quality of the SEMG signal is highly dependent on the conditioning circuit of the SEMG acquisition system. This paper presents the design of an SEMG conditioning circuit that can guarantee to collect high quality signal with high SNR such that it is immune to environmental noise. The conditioning circuit consists of four stages; consisting of an instrumentation amplifier that is used with a gain of around 250; 4th order band pass filter in the 20-500Hz frequency range as the two initial stages. The third stage is an amplifier with adjustable gain using a variable resistance; the gain could be changed from 1000 to 50000. In the final stage the signal is translated to meet the input requirements of data acquisition device or the ADC. Acquisition of accurate signals allows it to be analyzed for extracting the required characteristic features for medical and clinical applications. According to the experimental results, the value of SNR for collected signal is 52.4 dB which is higher than the commercial system, the power spectrum density (PSD) graph is also presented and it shows that the filter has eliminated the noise below 20 Hz.

  3. Mergers and Acquisitions - Case Study


    Vedele, Sebastiano


    The thesis generally talks about mergers & acquisitions, discussing definitions, differences and reasons behind an M&A. I have analyzed what is a merge and what is an acquisition. Why companies combine themselves through an M&A. What are advantages and disadvantages about an M&A. After that the work is followed by a case study, which focuses on Fiat and Chrysler. With regards to this point, the case touches all the steps of the agreement between the two car automakers providing numbers, perce...

  4. Simulation visualization through dynamic instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Bisset, K.R.


    The goal of the instrument composition system is to allow a simulation user to dynamically create instruments as a simulation executes. Instruments can include graphical displays, data collectors, and debugging aides. Instruments are made up of small building blocks which can be easily combined into larger, more complex instruments. Through the sue of an Attribute Server (a distributed publication/subscription mechanism), the actors and instruments in a simulation can interact without direct knowledge of each other. Instead, each actor publishes the attributes which it has available. An instrument subscribes to the attributes in which it is interested, and is notified whenever the value of one of these attribute changes. An instrument can also publish attributes for use by other instruments. Since the Attribute Server is distributed, the publisher of an attribute need not execute on the same machine as the subscriber. This allows CPU intensive data visualization to execute on separate machines from the simulation, minimizing the impact on the simulation.

  5. FHR Process Instruments

    Energy Technology Data Exchange (ETDEWEB)

    Holcomb, David Eugene [ORNL


    Fluoride salt-cooled High temperature Reactors (FHRs) are entering into early phase engineering development. Initial candidate technologies have been identified to measure all of the required process variables. The purpose of this paper is to describe the proposed measurement techniques in sufficient detail to enable assessment of the proposed instrumentation suite and to support development of the component technologies. This paper builds upon the instrumentation chapter of the recently published FHR technology development roadmap. Locating instruments outside of the intense core radiation and high-temperature fluoride salt environment significantly decreases their environmental tolerance requirements. Under operating conditions, FHR primary coolant salt is a transparent, low-vapor-pressure liquid. Consequently, FHRs can employ standoff optical measurements from above the salt pool to assess in-vessel conditions. For example, the core outlet temperature can be measured by observing the fuel s blackbody emission. Similarly, the intensity of the core s Cerenkov glow indicates the fission power level. Short-lived activation of the primary coolant provides another means for standoff measurements of process variables. The primary coolant flow and neutron flux can be measured using gamma spectroscopy along the primary coolant piping. FHR operation entails a number of process measurements. Reactor thermal power and core reactivity are the most significant variables for process control. Thermal power can be determined by measuring the primary coolant mass flow rate and temperature rise across the core. The leading candidate technologies for primary coolant temperature measurement are Au-Pt thermocouples and Johnson noise thermometry. Clamp-on ultrasonic flow measurement, that includes high-temperature tolerant standoffs, is a potential coolant flow measurement technique. Also, the salt redox condition will be monitored as an indicator of its corrosiveness. Both

  6. [First language acquisition research and theories of language acquisition]. (United States)

    Miller, S; Jungheim, M; Ptok, M


    In principle, a child can seemingly easily acquire any given language. First language acquisition follows a certain pattern which to some extent is found to be language independent. Since time immemorial, it has been of interest why children are able to acquire language so easily. Different disciplinary and methodological orientations addressing this question can be identified. A selective literature search in PubMed and Scopus was carried out and relevant monographies were considered. Different, partially overlapping phases can be distinguished in language acquisition research: whereas in ancient times, deprivation experiments were carried out to discover the "original human language", the era of diary studies began in the mid-19th century. From the mid-1920s onwards, behaviouristic paradigms dominated this field of research; interests were focussed on the determination of normal, average language acquisition. The subsequent linguistic period was strongly influenced by the nativist view of Chomsky and the constructivist concepts of Piaget. Speech comprehension, the role of speech input and the relevance of genetic disposition became the centre of attention. The interactionist concept led to a revival of the convergence theory according to Stern. Each of these four major theories--behaviourism, cognitivism, interactionism and nativism--have given valuable and unique impulses, but no single theory is universally accepted to provide an explanation of all aspects of language acquisition. Moreover, it can be critically questioned whether clinicians consciously refer to one of these theories in daily routine work and whether therapies are then based on this concept. It remains to be seen whether or not new theories of grammar, such as the so-called construction grammar (CxG), will eventually change the general concept of language acquisition.

  7. CARMENES instrument overview (United States)

    Quirrenbach, A.; Amado, P. J.; Caballero, J. A.; Mundt, R.; Reiners, A.; Ribas, I.; Seifert, W.; Abril, M.; Aceituno, J.; Alonso-Floriano, F. J.; Ammler-von Eiff, M.; Antona Jiménez, R.; Anwand-Heerwart, H.; Azzaro, M.; Bauer, F.; Barrado, D.; Becerril, S.; Béjar, V. J. S.; Benítez, D.; Berdiñas, Z. M.; Cárdenas, M. C.; Casal, E.; Claret, A.; Colomé, J.; Cortés-Contreras, M.; Czesla, S.; Doellinger, M.; Dreizler, S.; Feiz, C.; Fernández, M.; Galadí, D.; Gálvez-Ortiz, M. C.; García-Piquer, A.; García-Vargas, M. L.; Garrido, R.; Gesa, L.; Gómez Galera, V.; González Álvarez, E.; González Hernández, J. I.; Grözinger, U.; Guàrdia, J.; Guenther, E. W.; de Guindos, E.; Gutiérrez-Soto, J.; Hagen, H.-J.; Hatzes, A. P.; Hauschildt, P. H.; Helmling, J.; Henning, T.; Hermann, D.; Hernández Castaño, L.; Herrero, E.; Hidalgo, D.; Holgado, G.; Huber, A.; Huber, K. F.; Jeffers, S.; Joergens, V.; de Juan, E.; Kehr, M.; Klein, R.; Kürster, M.; Lamert, A.; Lalitha, S.; Laun, W.; Lemke, U.; Lenzen, R.; López del Fresno, Mauro; López Martí, B.; López-Santiago, J.; Mall, U.; Mandel, H.; Martín, E. L.; Martín-Ruiz, S.; Martínez-Rodríguez, H.; Marvin, C. J.; Mathar, R. J.; Mirabet, E.; Montes, D.; Morales Muñoz, R.; Moya, A.; Naranjo, V.; Ofir, A.; Oreiro, R.; Pallé, E.; Panduro, J.; Passegger, V.-M.; Pérez-Calpena, A.; Pérez Medialdea, D.; Perger, M.; Pluto, M.; Ramón, A.; Rebolo, R.; Redondo, P.; Reffert, S.; Reinhardt, S.; Rhode, P.; Rix, H.-W.; Rodler, F.; Rodríguez, E.; Rodríguez-López, C.; Rodríguez-Pérez, E.; Rohloff, R.-R.; Rosich, A.; Sánchez-Blanco, E.; Sánchez Carrasco, M. A.; Sanz-Forcada, J.; Sarmiento, L. F.; Schäfer, S.; Schiller, J.; Schmidt, C.; Schmitt, J. H. M. M.; Solano, E.; Stahl, O.; Storz, C.; Stürmer, J.; Suárez, J. C.; Ulbrich, R. G.; Veredas, G.; Wagner, K.; Winkler, J.; Zapatero Osorio, M. R.; Zechmeister, M.; Abellán de Paco, F. J.; Anglada-Escudé, G.; del Burgo, C.; Klutsch, A.; Lizon, J. L.; López-Morales, M.; Morales, J. C.; Perryman, M. A. C.; Tulloch, S. M.; Xu, W.


    This paper gives an overview of the CARMENES instrument and of the survey that will be carried out with it during the first years of operation. CARMENES (Calar Alto high-Resolution search for M dwarfs with Exoearths with Near-infrared and optical Echelle Spectrographs) is a next-generation radial-velocity instrument under construction for the 3.5m telescope at the Calar Alto Observatory by a consortium of eleven Spanish and German institutions. The scientific goal of the project is conducting a 600-night exoplanet survey targeting ~ 300 M dwarfs with the completed instrument. The CARMENES instrument consists of two separate echelle spectrographs covering the wavelength range from 0.55 to 1.7 μm at a spectral resolution of R = 82,000, fed by fibers from the Cassegrain focus of the telescope. The spectrographs are housed in vacuum tanks providing the temperature-stabilized environments necessary to enable a 1 m/s radial velocity precision employing a simultaneous calibration with an emission-line lamp or with a Fabry-Perot etalon. For mid-M to late-M spectral types, the wavelength range around 1.0 μm (Y band) is the most important wavelength region for radial velocity work. Therefore, the efficiency of CARMENES has been optimized in this range. The CARMENES instrument consists of two spectrographs, one equipped with a 4k x 4k pixel CCD for the range 0.55 - 1.05 μm, and one with two 2k x 2k pixel HgCdTe detectors for the range from 0.95 - 1.7μm. Each spectrograph will be coupled to the 3.5m telescope with two optical fibers, one for the target, and one for calibration light. The front end contains a dichroic beam splitter and an atmospheric dispersion corrector, to feed the light into the fibers leading to the spectrographs. Guiding is performed with a separate camera; on-axis as well as off-axis guiding modes are implemented. Fibers with octagonal cross-section are employed to ensure good stability of the output in the presence of residual guiding errors. The

  8. In vivo testing of a prototype system providing simultaneous white light and near infrared autofluorescence image acquisition for detection of bladder cancer (United States)

    Jacobson, Michael C.; deVere White, Ralph; Demos, Stavros G.


    A prototype instrument developed to provide simultaneously ordinary visual endoscopy together with near infrared (NIR) autofluorescence imaging via parallel image acquisition is demonstrated. The two images are recorded concurrently and the instrument interfaces with any ordinary endoscope. Preliminary results of a pilot study focused on imaging of bladder tumors in vivo using this instrumentation are presented. The experimental results demonstrate the capabilities of this instrumentation design, imaging methodology, and define the current limitation for further development of the system.

  9. Microcomputer-controlled ultrasonic data acquisition system. [LMFBR

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, W.A. Jr.


    The large volume of ultrasonic data generated by computer-aided test procedures has necessitated the development of a mobile, high-speed data acquisition and storage system. This approach offers the decided advantage of on-site data collection and remote data processing. It also utilizes standard, commercially available ultrasonic instrumentation. This system is controlled by an Intel 8080A microprocessor. The MCS80-SDK microcomputer board was chosen, and magnetic tape is used as the storage medium. A detailed description is provided of both the hardware and software developed to interface the magnetic tape storage subsystem to Biomation 8100 and Biomation 805 waveform recorders. A boxcar integrator acquisition system is also described for use when signal averaging becomes necessary. Both assembly language and machine language listings are provided for the software.

  10. Spectroscopic instrumentation fundamentals and guidelines for astronomers

    CERN Document Server

    Eversberg, Thomas


    In order to analyze the light of cosmic objects, particularly at extremely great distances, spectroscopy is the workhorse of astronomy. In the era of very large telescopes, long-term investigations are mainly performed with small professional instruments. Today they can be done using self-designed spectrographs and highly efficient CCD cameras, without the need for large financial investments.   This book explains the basic principles of spectroscopy, including the fundamental optical constraints and all mathematical aspects needed to understand the working principles in detail. It covers the complete theoretical and practical design of standard and Echelle spectrographs. Readers are guided through all necessary calculations, enabling them to engage in spectrograph design. The book also examines data acquisition with CCD cameras and fiber optics, as well as the constraints of specific data reduction and possible sources of error. In closing it briefly highlights some main aspects of the research on massive s...

  11. Small instrument to volcanic seismic signals (United States)

    Carreras, Normandino; Gomariz, Spartacus; Manuel, Antoni


    Currently, the presence of volcanoes represents a threat to their local populations, and for this reason, scientific communities invest resources to monitor seismic activity of an area, and to obtain information to identify risk situations. To perform such monitoring, it can use different general purpose acquisition systems commercially available, but these devices do not meet to the specifications of reduced dimensions, low weight, low power consumption and low cost. These features allow the system works in autonomous mode for a long period of time, and it makes easy to be carried and to be installed. In the line of designing a volcanic acquisition system with the previously mentioned specifications, exists the Volcanology Department of CSIC, developers of a system with some of these specifications. The objective of this work is to improve the energy consumption requirements of the previous system, providing three channels of data acquisition and with the possibility to transmit data acquisition via radio frequency to a base station, allowing operation it in remote mode. The developed acquisition system consists of three very low-power acquisition modules of Texas Instruments (ADS1246), and this is designed to capture information of the three coordinate axes. A microprocessor also of Texas Instruments (MSP430F5438) is used to work in low-power, due to it is ready to run this consumption and also takes advantage the power save mode in certain moments when system is not working. This system is configurable by serial port, and it has a SD memory to storage data. Contrast to the previous system, it has a RF communication module incorporated specially to work in remote mode of Lynx (YLX-TRM8053-025-05), and boasts also with a GPS module which keeps the time reference synchronized with module of SANAV (GM-1315LA). Thanks to this last selection of components, it is designed a small system about 106 x 106 mm. Assuming that the power supply system is working during all the

  12. Suffix Knowledge: Acquisition and Applications (United States)

    Ward, Jeremy; Chuenjundaeng, Jitlada


    The purpose of this study is to investigate L2 learners' knowledge of complex word part analysis ("word-building"), with particular reference to two issues: suffix acquisition and to the use of word families as a counting tool. Subjects were two groups of EAP students in a Thai university. Results suggest that (1) the use of word…

  13. Instructional Model for Concept Acquisition. (United States)

    Tennyson, Robert D.

    The purpose of this paper is to demonstrate the feasibility of applying research variables for concept acquisition into a generalized instructional model for teaching concepts. This paper does not present the methodology for the decision/selection stages in designing the actual instruction task, but offers references to other sources which give…

  14. [Language acquisition and statistical learning]. (United States)

    Breitenstein, C; Knecht, S


    Statistical learning is a basic mechanism of information processing in the human brain. The purpose lies in the extraction of probabilistic regularities from the multitude of sensory inputs. Principles of statistical learning contribute significantly to language acquisition and presumably also to language recovery following stroke. The empirical database presented in this manuscript demonstrates that the process of word segmentation, acquisition of a lexicon, and acquisition of simple grammatical rules can be entirely explained through statistical learning. Statistical learning is mediated by changes in synaptic weights in neuronal networks. The concept therefore stands at the transition to molecular biology and pharmacology of the neuronal synapse. It still remains to be shown if all aspects of language acquisition can be explained through statistical learning and which regions of the brain are involved in or capable of statistical learning. Principles of effective language training are obvious already. Most important is the massive, repeated interactive exposure. Conscious processing of the stimulus material may not be essential. The crucial principle is a high cooccurrence of language and corresponding sensory processes. This requires a more intense training frequency than traditional aphasia treatment programs provide.

  15. Profiling Vocabulary Acquisition in Irish (United States)

    O'Toole, Ciara; Fletcher, Paul


    Investigations into early vocabulary development, including the timing of the acquisition of nouns, verbs and closed-class words, have produced conflicting results, both within and across languages. Studying vocabulary development in Irish can contribute to this area, as it has potentially informative features such as a VSO word order, and…

  16. Analog Input Data Acquisition Software (United States)

    Arens, Ellen


    DAQ Master Software allows users to easily set up a system to monitor up to five analog input channels and save the data after acquisition. This program was written in LabVIEW 8.0, and requires the LabVIEW runtime engine 8.0 to run the executable.

  17. Essays on mergers and acquisitions

    NARCIS (Netherlands)

    Faelten, A.I.


    “Essays on Mergers and Acquisitions" tackles some of the most prominent business challenges related to M&A activity. The Introduction examines the reasons why deals fail through well-known case studies; Chapter 1 presents a new index measuring countries M&A maturity worldwide; Chapter 2 focus on the

  18. Behavioural View of Language Acquisition

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 13; Issue 5. Behavioural View of Language Acquisition. Rajeev Sangal. Book Review Volume 13 Issue 5 May 2008 pp 487-489. Fulltext. Click here to view fulltext PDF. Permanent link: ...

  19. Language Acquisition and Language Revitalization (United States)

    O'Grady, William; Hattori, Ryoko


    Intergenerational transmission, the ultimate goal of language revitalization efforts, can only be achieved by (re)establishing the conditions under which an imperiled language can be acquired by the community's children. This paper presents a tutorial survey of several key points relating to language acquisition and maintenance in children,…

  20. Micromachining inertial instruments (United States)

    Weinberg, Marc S.; Bernstein, Jonathan J.; Borenstein, Jeffrey T.; Campbell, J.; Cousens, J.; Cunningham, Robert K.; Fields, R.; Greiff, Paul; Hugh, Brenda; Niles, Les; Sohn, Jerome B.


    Draper Laboratory, using silicon microfabrication techniques to achieve high yields by batch processing, has been developing miniature microelectromechanical instruments for over 10 years. During this time, considerable progress has been made in the development and fabrication of micromechanical gyroscopes, accelerometers, and acoustic sensors. Inertial instruments have become a worldwide research and commercial topic. Draper gyroscopes and accelerometers have been fabricated with measurement ranges from 50 to 500 deg/s and 10 to 100,000 g, respectively. In gyroscopes, stabilities are 20 deg/h in room temperature tests and 4.4 deg/h applying 0.3 degrees C thermal control. For accelerometers, less than 1 mg has been demonstrated in room temperature tests. These units have performed successfully across a temperature range of -40 to 85 degrees C, and have survived 80,000- to 120,000-g shock tests along all axes. Continuing development activities are expected to yield over an order of magnitude in performance enhancement. These micromechanical instruments are built using a silicon wafer process that results in crystal silicon structures that are anodically bonded on a Pyrex substrate that contains sensing and control electrodes. This silicon-on-glass configuration has low stray capacitance, and is ideally suited for hybrid or flip-chip bonding technology. Draper's inertial sensors incorporate excellent fabrication, however, building the silicon and Pyrex sensor chip is only one of many important contributions in a complete sensor system. Other equally important steps include: 1) electronics and application-specific integrated circuits (ASICs) 2) packaging, 3) test, and 4) modeling and analysis. This presentation focuses on sensor fabrication. Draper's accelerometers and gyroscopes and the dissolved wafer fabrication process are described. The evolution of gyro design, fabrication, and performance is summarized. Garnered through experience in both conventional and

  1. A longitudinal study on intercultural awareness and foreign language acquisition in the Netherlands

    NARCIS (Netherlands)

    Korzilius, H.P.L.M.; Hooft, A.P.J.V. van; Planken, B.C.


    In a longitudinal study we assessed the effect of a four-year International Business Communication program at a university in the Netherlands on students’ intercultural awareness and foreign language acquisition. In pre-test and post-test a measurement instrument featuring everyday (monocultural and

  2. Research Knowledge Assessment: A Study of MSW Students' Acquisition and Retention of Research Knowledge (United States)

    Secret, Mary; Abell, Melissa L.; Ward, Christopher J.; Charles, Jennifer L. K.; Perkins, Nathan H.


    In response to the need for meaningful data about student learning in research courses, we developed and implemented the Research Knowledge Assessment instrument to measure MSW student acquisition, application, and retention of research knowledge over a 3-year period across the research curriculum. Initial findings indicated that students entered…

  3. General purpose interface bus for personal computers used in wind tunnel data acquisition (United States)

    Puram, Chith K.


    The use of the general purpose interface bus IEEE-488 to met the special requirements of wind tunnel testing involving PCs is discussed. The gearing of instrumentation to minimize test time, the choice of software to meet computer memory constraints, the use of graphics for improved use of tunnel run time, and the choice of data acquisition equipment to remove bottlenecks are addressed.

  4. Factors Influencing the Acquisition of Employability Skills by Students of Selected Technical Secondary School in Malaysia (United States)

    Dania, Jovinia; Bakar, Ab Rahim; Mohamed, Shamsiah


    The main purpose of the study was to assess the acquisition of employability skills by vocational students in Malaysia. A total of 214 students participated in the study. We used the SCANS instrument to assess vocational students' employability skills. The overall mean of vocational secondary students' employability skills was 3.81 (SD = 0.34).…

  5. Buffer gas acquisition and storage (United States)

    Parrish, Clyde F.; Lueck, Dale E.; Jennings, Paul A.


    The acquisition and storage of buffer gases (primarily argon and nitrogen) from the Mars atmosphere provides a valuable resource for blanketing and pressurizing fuel tanks and as a buffer gas for breathing air for manned missions. During the acquisition of carbon dioxide (CO2), whether by sorption bed or cryo-freezer, the accompanying buffer gases build up in the carbon dioxide acquisition system, reduce the flow of CO2 to the bed, and lower system efficiency. It is this build up of buffer gases that provide a convenient source, which must be removed, for efficient capture of CO2. Removal of this buffer gas barrier greatly improves the charging rate of the CO2 acquisition bed and, thereby, maintains the fuel production rates required for a successful mission. Consequently, the acquisition, purification, and storage of these buffer gases are important goals of ISRU plans. Purity of the buffer gases is a concern e.g., if the CO2 freezer operates at 140 K, the composition of the inert gas would be approximately 21 percent CO2, 50 percent nitrogen, and 29 percent argon. Although there are several approaches that could be used, this effort focused on a hollow-fiber membrane (HFM) separation method. This study measured the permeation rates of CO2, nitrogen (N2), and argon (Ar) through a multiple-membrane system and the individual membranes from room temperature to 193 K and 10 kPa to 300 kPa. Concentrations were measured with a gas chromatograph. The end result was data necessary to design a system that could separate CO2, N2, and Ar. .

  6. Buffer Gas Acquisition and Storage (United States)

    Parrish, Clyde F.; Lueck, Dale E.; Jennings, Paul A.; Callahan, Richard A.; Delgado, H. (Technical Monitor)


    The acquisition and storage of buffer gases (primarily argon and nitrogen) from the Mars atmosphere provides a valuable resource for blanketing and pressurizing fuel tanks and as a buffer gas for breathing air for manned missions. During the acquisition of carbon dioxide (CO2), whether by sorption bed or cryo-freezer, the accompanying buffer gases build up in the carbon dioxide acquisition system, reduce the flow of CO2 to the bed, and lower system efficiency. It is this build up of buffer gases that provide a convenient source, which must be removed, for efficient capture Of CO2 Removal of this buffer gas barrier greatly improves the charging rate of the CO2 acquisition bed and, thereby, maintains the fuel production rates required for a successful mission. Consequently, the acquisition, purification, and storage of these buffer gases are important goals of ISRU plans. Purity of the buffer gases is a concern e.g., if the CO, freezer operates at 140 K, the composition of the inert gas would be approximately 21 percent CO2, 50 percent nitrogen, and 29 percent argon. Although there are several approaches that could be used, this effort focused on a hollow-fiber membrane (HFM) separation method. This study measured the permeation rates of CO2, nitrogen (ND, and argon (Ar) through a multiple-membrane system and the individual membranes from room temperature to 193K and 10 kpa to 300 kPa. Concentrations were measured with a gas chromatograph that used a thermoconductivity (TCD) detector with helium (He) as the carrier gas. The general trend as the temperature was lowered was for the membranes to become more selective, In addition, the relative permeation rates between the three gases changed with temperature. The end result was to provide design parameters that could be used to separate CO2 from N2 and Ar.

  7. Instruments of Transformative Governance

    DEFF Research Database (Denmark)

    Borrás, Susana

    production and distribution channels. PDPs aim at overcoming current market and government failures by pooling resources in the attempt to solve this global social challenge. Thus, PDPs are a case of instruments of transformative research and innovation, operating in a transnational governance context....... They exhibit three novelties: they address strategic long-term problems in a holistic manner, set substantive output-oriented goals, and are implemented through new organizational structures. After characterizing the different types of current PDPs and the context in which they emerged, the paper examines...

  8. Jedem Kind ein Instrument

    DEFF Research Database (Denmark)

    Holst, Finn


    I forbindelse med skolereformen 2014 er der kommet øget fokus på samarbejdet mellem musikskole og folkeskole (grundskole). En kortlægningsundersøgelse viste op til reformen, at så godt som alle musikskoler har et samarbejde med grundskolen, mens der er en del folkeskoler, som ikke har et samarbej...... muligheder. Jedem Kind ein Instrument (JeKi) er et grundskoleprogram med instrumentundervisning, som bygger på samarbejde mellem musikskole og grundskole. Der indgår over 70.000 elever årligt, og der er etableret et omfattende forskningsprogram....

  9. Leir beam instrumentation

    CERN Document Server

    Bal, C; Burger, S; Dutriat, C; Gasior, M; Lefèvre, T; Lenardon, F; Odier, P; Raich, U; Soby, L; Tan, J; Tranquille, G; Vuitton, C


    The Low Energy Ion Ring (LEIR) is central to the “Ions for LHC” project. Its role is to transform a serie of long low intensity ion pulses from Linac 3, into short high density pulses, which will be further accelerated in the PS and SPS rings, before injection into LHC. To do so the injected pulses are stacked and phase space cooled using electron cooling, before acceleration to the ejection energy of 72 MEV/u. This note describes different types of instruments which will be installed in the LEIR ring and transfer lines.

  10. Payment Instrument Characteristics

    DEFF Research Database (Denmark)

    Holst, Jacques; Kjeldsen, Martin; Hedman, Jonas


    Over the last decade, we have witnessed payment innovations that fundamentally have changed the ways we pay. Payment innovations, such as mobile payments and on-line banking, include characteristics or features that are essential to understand if we want to know how and why payers choose among...... payment innovations. Using the Repertory Grid technique to explore 15 payers’ perception of six payment instruments, including coins, banknotes, debit cards, credit cards, mobile payments, and on-line banking, we identify 16 payment characteristics. The characteristics aggregate seventy-six unique...... features. Many of the characteristics and one of the categories are completely novel and unaccounted for in previous works....

  11. Memory strategies and ESL vocabulary acquisition

    Directory of Open Access Journals (Sweden)

    Carisma Dreyer


    Full Text Available This article compares the effectiveness of three learning strategies (memory strategies for ESL vocabulary acquisition. Four intact ESL classes were divided into one control group and three treatment groups (keyword, semantic, and keyword-semantic. These Afrikaans-speaking standard 6 pupils then received 4 days of instruction. Both multiplechoice and cued-recall instruments were used to measure effects both 1 day and 9 days after instruction. The results indicated that for both the multiple-choice and cued-recall tests the combined keyword-semantic strategy differed statistically Significantly as well as practically significantly from the keyword method. The results, therefore, suggest that the combined keyword-semantic strategy increased retention above the other strategies. Hierdie artikel vergelyk die effektiwiteit van drie taalleerstrategiee (geheue strategiee vir die aanleer van woordeskat met mekaar. Vier intak Engels tweedetaal klasse is verdeel in een kontrole groep en drie eksperimentele groepe (sleutelwoord, semantiese en 'n kombinasie van die sleutelwoord-semantiese strategiee. 'n Groep Afrikaanssprekende standerd ses leerlinge het vir 'n tydperk van vier dae onderrig in elk van bogenoemde strategiee ontvang. Multikeuse en "cued-recall" instrumente is gebruik om die effek van onderrig beide een dag en nege dae na eksperimentering te bepaal. Die resultate het aangetoon dat die gekombineerde sleutelwoord-semantiese strategie statisties betekenisvol sowel as prakties betekenisvol van die sleutelwoord strategie en die kontrole groep verskil het. Dit wil dus voorkom asof die gekombineerde sleutelwoord-semantiese strategie die mees belowende strategie is ten opsigte van die retensie van woordeskat.

  12. Calibration of "Babyline" RP instruments

    CERN Multimedia


      If you have old RP instrumentation of the “Babyline” type, as shown in the photo, please contact the Radiation Protection Group (Joffrey Germa, 73171) to have the instrument checked and calibrated. Thank you. Radiation Protection Group

  13. Developments of a new data acquisition system at ANNRI (United States)

    Nakao, T.; Terada, K.; Kimura, A.; Nakamura, S.; Iwamoto, O.; Harada, H.; Katabuchi, T.; Igashira, M.; Hori, J.


    A new data acquisition system (DAQ system) has been developed at the Accurate Neutron-Nucleus Reaction Measurement Instrument (ANNRI) facility in the Japan Proton Accelerator Research Complex, Materials and Life Science Experimental Facility (J-PARC/MLF). DAQ systems for both the Ge detector system and the Li-glass detector system were tested by using a gold sample. The applicability of the time-of-flight method was checked. System performance was evaluated on the basis of digital conversion nonlinearity, energy resolution, multi-channel coincidence and dead time.

  14. An Instrumental Innovation (United States)


    Think of guitars and you think of rock and country music, or the vigorous rhythms of the gypsy flamenco, or perhaps the classical strumming of a Segovia. About the last thing you would associate with guitars is aerospace technology. Yet there is a connection. A whole family of quality guitars is an outgrowth of helicopter rotor research conducted for the military services and NASA by an aerospace contractor. These musical spinoffs, commercially available and rapidly gaining in popularity, are the Ovation guitar line, manufactured by Ovation Instruments, Inc., Bloomfield, Connecticut. Ovation Instruments is a subsidiary of Kaman Corporation, a diversified company originally formed to develop and build helicopters. A helicopter's rotor system, with thousands of moving parts, is highly susceptible to vibration. For rotor efficiency, vibration must be "dampened," or reduced. Like other helicopter builders, Kaman Corporation spent years of research toward that end. The technology thus developed, together with the availability of staff experts in vibration engineering, sparked an idea in the mind of the company's president and founder, Charles H. Karnan. A guitarist of professional caliber, Kaman reasoned that vibration-dampening technology could be turned around to enhance vibration and thereby produce a guitar with superior sound.

  15. Far ultraviolet instrument technology (United States)

    Paxton, Larry J.; Schaefer, Robert K.; Zhang, Yongliang; Kil, Hyosub


    The far ultraviolet (FUV) spectral range (from about 115 nm to 180 nm) is one of the most useful spectral regions for characterizing the upper atmosphere (thermosphere and ionosphere). The principal advantages are that there are FUV signatures of the major constituents of the upper atmosphere as well as the signatures of the high-latitude energy inputs. Because of the absorption by thermospheric O2, the FUV signatures are seen against a "black" background, i.e., one that is not affected by ground albedo or clouds and, as a consequence, can make useful observations of the aurora during the day or when the Moon is above the horizon. In this paper we discuss the uses of FUV remote sensing, summarize the various techniques, and discuss the technological challenges. Our focus is on a particular type of FUV instrument, the scanning imaging spectrograph or SIS: an instrument exemplified by the Defense Meteorological Satellite Program Special Sensor Ultraviolet Imager and Thermosphere Ionosphere Mesosphere Energetics and Dynamics Global Ultraviolet Imager. The SIS combines spatial imaging of the disk with limb profiles as well as spectral information at each point in the scan.

  16. The QUIET Instrument

    Energy Technology Data Exchange (ETDEWEB)

    Bischoff, C.; et al.


    The Q/U Imaging ExperimenT (QUIET) is designed to measure polarization in the Cosmic Microwave Background, targeting the imprint of inflationary gravitational waves at large angular scales ({approx}1{sup o}). Between 2008 October and 2010 December, two independent receiver arrays were deployed sequentially on a 1.4m side-fed Dragonian telescope. The polarimeters which form the focal planes use a highly compact design based on High Electron Mobility Transistors (HEMTs) that provides simultaneous measurements of the Stokes parameters Q, U, and I in a single module. The 17-element Q-band polarimeter array, with a central frequency of 43.1 GHz, has the best sensitivity (69 {mu}Ks{sup 1/2}) and the lowest instrumental systematic errors ever achieved in this band, contributing to the tensor-to-scalar ratio at r < 0:1. The 84-element W-band polarimeter array has a sensitivity of 87 {mu}Ks{sup 1/2} at a central frequency of 94.5 GHz. It has the lowest systematic errors to date, contributing at r < 0:01. The two arrays together cover multipoles in the range {ell} {approx} 25 -- 975. These are the largest HEMT-based arrays deployed to date. This article describes the design, calibration, performance of, and sources of systematic error for the instrument.

  17. Balances instruments, manufacturers, history

    CERN Document Server

    Robens, Erich; Kiefer, Susanne


    The book deals mainly with direct mass determination by means of a conventional balances. It covers the history of the balance from the beginnings in Egypt earlier than 3000 BC to recent developments. All balance types are described with emphasis on scientific balances. Methods of indirect mass determination, which are applied to very light objects like molecules and the basic particles of matter and celestial bodies, are included.  As additional guidance, today’s manufacturers are listed and the profile of important companies is reviewed. Several hundred photographs, reproductions and drawings show instruments and their uses. This book includes commercial weighing instruments for merchandise and raw materials in workshops as well as symbolic weighing in the ancient Egyptian’s ceremony of ‘Weighing of the Heart’, the Greek fate balance, the Roman  Justitia, Juno Moneta and Middle Ages scenes of the Last Judgement with Jesus or St. Michael and of modern balances. The photographs are selected from the...

  18. Instrument Remote Control via the Astronomical Instrument Markup Language (United States)

    Sall, Ken; Ames, Troy; Warsaw, Craig; Koons, Lisa; Shafer, Richard


    The Instrument Remote Control (IRC) project ongoing at NASA's Goddard Space Flight Center's (GSFC) Information Systems Center (ISC) supports NASA's mission by defining an adaptive intranet-based framework that provides robust interactive and distributed control and monitoring of remote instruments. An astronomical IRC architecture that combines the platform-independent processing capabilities of Java with the power of Extensible Markup Language (XML) to express hierarchical data in an equally platform-independent, as well as human readable manner, has been developed. This architecture is implemented using a variety of XML support tools and Application Programming Interfaces (API) written in Java. IRC will enable trusted astronomers from around the world to easily access infrared instruments (e.g., telescopes, cameras, and spectrometers) located in remote, inhospitable environments, such as the South Pole, a high Chilean mountaintop, or an airborne observatory aboard a Boeing 747. Using IRC's frameworks, an astronomer or other scientist can easily define the type of onboard instrument, control the instrument remotely, and return monitoring data all through the intranet. The Astronomical Instrument Markup Language (AIML) is the first implementation of the more general Instrument Markup Language (IML). The key aspects of our approach to instrument description and control applies to many domains, from medical instruments to machine assembly lines. The concepts behind AIML apply equally well to the description and control of instruments in general. IRC enables us to apply our techniques to several instruments, preferably from different observatories.

  19. Digital instrumentation and management of dead time: First results on a NaI well-type detector setup

    Energy Technology Data Exchange (ETDEWEB)

    Censier, B., E-mail: censier@csnsm.in2p3.f [CEA, LIST, Laboratoire National Henri Becquerel (LNE-LNHB), F-91191 Gif-sur-Yvette (France); Bobin, C.; Bouchard, J.; Aubineau-Laniece, I. [CEA, LIST, Laboratoire National Henri Becquerel (LNE-LNHB), F-91191 Gif-sur-Yvette (France)


    The LNE-LNHB is engaged in a development program on digital instrumentation, the first step being the instrumentation of a NaI well-type detector set-up. The prototype acquisition card and its technical specifications are presented together with the first comparison with the classical NIM-based acquisition chain, for counting rates up to 100 kcps. The digital instrumentation is shown to be counting-loss free in this range. This validates the main option adopted in this project, namely the implementation of an extending dead time with live-time measurement already successfully used in the MTR2 NIM module developed at LNE-LNHB.

  20. 48 CFR 307.104-70 - Acquisition strategy. (United States)


    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Acquisition strategy. 307... AND ACQUISITION PLANNING ACQUISITION PLANNING Acquisition Planning 307.104-70 Acquisition strategy... designated by the HHS CIO, DASFMP, the CAO, or the cognizant HCA) shall prepare an acquisition strategy using...

  1. CLIC-ACM: Acquisition and Control System

    CERN Document Server

    Bielawski, B; Magnoni, S


    CLIC [1] (Compact Linear Collider) is a world-wide collaboration to study the next terascale lepton collider, relying upon a very innovative concept of two-beamacceleration. In this scheme, the power is transported to the main accelerating structures by a primary electron beam. The Two Beam Module (TBM) is a compact integration with a high filling factor of all components: RF, Magnets, Instrumentation, Vacuum, Alignment and Stabilization. This paper describes the very challenging aspects of designing the compact system to serve as a dedicated Acquisition & Control Module (ACM) for all signals of the TBM. Very delicate conditions must be considered, in particular radiation doses that could reach several kGy in the tunnel. In such severe conditions shielding and hardened electronics will have to be taken into consideration. In addition, with more than 300 ADC&DAC channels per ACM and about 21000 ACMs in total, it appears clearly that power consumption will be an important issue. It is also obvious that...

  2. Adherence level and knowledge about psychopharmacological treatment among patients discharged from psychiatric internment Grado de adhesión y conocimiento sobre tratamiento psicofarmacológico entre pacientes egresados de internación psiquiátrica Grau de adesão e conhecimento sobre tratamento psicofarmacológico entre pacientes egressos de internação psiquiátrica

    Directory of Open Access Journals (Sweden)

    Lucilene Cardoso


    Full Text Available This exploratory, descriptive and prospective study aimed to identify the degree of adherence to psychopharmacological treatment of patients who were discharged from psychiatric hospitalization and their knowledge about their prescription and diagnosis. The study was carried out at a Mental Health Service. The sample consisted of all service clients who were discharged from psychiatric hospitalization in the data collection period. A Sociodemographic Questionnaire and the Morisky-Green Test were the instruments used. Data were analyzed through central trend measures. In total, 48 patients participated in the study. Regarding adherence, 70.8% of them showed a low adherence level to psychopharmacological treatment. Moreover, only twenty-one patients knew what their diagnosis was and most did not know or partially knew the name and dose of all prescribed medications.El objetivo de este trabajo fue identificar el grado de adhesión al tratamiento psicofarmacológico de los pacientes egresados de internación psiquiátrica y evaluar su conocimiento en cuanto a su prescripción y diagnóstico. Se trata de un estudio exploratorio, descriptivo, prospectivo, realizado en un Núcleo de Salud Mental. La muestra fue compuesta por todos los clientes de este servicio que tuvieron alta de internación psiquiátrica en el período de recolección siendo utilizado un Cuestionario sociodemográfico y la Prueba de Adhesión de Morisky-Green como instrumentos. Los datos fueron analizados por medidas de tendencia central. Hicieron parte de la muestra 48 pacientes; en relación a la adhesión, se observó que 70,8% de ellos fueron clasificados con bajo grado de adhesión al tratamiento psicofarmacológico. Además de eso, apenas veintiún pacientes sabían informar cual era su diagnóstico y la mayoría de ellos no sabía o sabía parcialmente el nombre y dosis de todos los medicamentos que le fueron prescritos.O objetivo deste trabalho foi identificar o grau de ades

  3. Mergers and acquisitions processes in Ukraine




    The paper deals with characteristics of merges and acquisitions market in Ukraine. The study describes main directions and motives of integration processes at domestic enterprises. Efficient ways are suggested to improve processes of merges and acquisitions in Ukraine.

  4. Technological Integration of Acquisitions in Digital Industries

    DEFF Research Database (Denmark)

    Henningsson, Stefan; Toppenberg, Gustav


    Acquisitions have become essential tools to retain the technological edge in digital industries. This paper analyses the technological integration challenges in such acquisitions. Acquirers in digital industries are typically platform leaders in platform markets. They acquire (a) other platform...

  5. Acquisition management of the Global Transportation Network (United States)


    This report discusses the acquisition management of the Global transportation Network by the U.S. Transportation Command. This report is one in a series of audit reports addressing DoD acquisition management of information technology systems. The Glo...

  6. Laser-induced photo emission detection: data acquisition based on light intensity counting (United States)

    Yulianto, N.; Yudasari, N.; Putri, K. Y.


    Laser Induced Breakdown Detection (LIBD) is one of the quantification techniques for colloids. There are two ways of detection in LIBD: optical detection and acoustic detection. LIBD is based on the detection of plasma emission due to the interaction between particle and laser beam. In this research, the changing of light intensity during plasma formations was detected by a photodiode sensor. A photo emission data acquisition system was built to collect and transform them into digital counts. The real-time system used data acquisition device National Instrument DAQ 6009 and LABVIEW software. The system has been tested on distilled water and tap water samples. The result showed 99.8% accuracy by using counting technique in comparison to the acoustic detection with sample rate of 10 Hz, thus the acquisition system can be applied as an alternative method to the existing LIBD acquisition system.

  7. Data Acquisition System for Electric Vehicle's Driving Motor Test Bench Based on VC++ (United States)

    Qiang, Song; Chenguang, Lv

    In order to solve such problems as great labor intensity, high cost, low efficiency and accuracy during the performance experiment for driving motor system of electric vehicles, and realize data acquisition automatically and synchronously, a data acquisition system for driving motor test bench based on visual instruments is designed. This data acquisition system can be used to obtain the driving motor's parameters of currents and voltages at the same time. This system's hardware is based on electric vehicle's motor test bench in Beijing Institute of Technology, and combined with PXI2010 data acquisition card from ADLINK Company. Visual c++ software is adopted as development tool. In this paper, the design and realization of the hardware and software are presented. Experiment results show that this system improves the efficiency and quality of testing task with high utility. And experiment data can be obtained accurately.

  8. Beijing opera percussion instrument dataset




    The Beijing Opera percussion instrument dataset is a collection of audio examples of individual strokes spanning the four percussion instrument classes used in Beijing Opera (Jingju, 京剧)./nBeijing Opera uses six main percussion instruments that can be grouped into four classes: /n/n1/ Bangu (Clapper-drum) consisting of Ban (the clapper, a wooden board-­shaped instrument) + danpigu (a wooden drum struck by two wooden sticks)/n2/ Naobo (Cymbals) consisting of two cymbal instruments Qibo+Danao/n...

  9. UAVSAR Instrument: Current Operations and Planned Upgrades (United States)

    Lou, Yunling; Hensley, Scott; Chao, Roger; Chapin, Elaine; Heavy, Brandon; Jones, Cathleen; Miller, Timothy; Naftel, Chris; Fratello, David


    The Uninhabited Aerial Vehicle Synthetic Aperture Radar (UAVSAR) instrument is a pod-based Lband polarimetric synthetic aperture radar (SAR), specifically designed to acquire airborne repeat track SAR data for differential interferometric measurements. This instrument is currently installed on the NASA Gulfstream- III (G-III) aircraft with precision real-time Global Positioning System (GPS) and a sensor-controlled flight management system for precision repeat-pass data acquisitions. UAVSAR has conducted engineering and preliminary science data flights since October 2007 on the G-III. We are porting the radar to the Global Hawk Unmanned Airborne Vehicle (UAV) to enable long duration/long range data campaigns. We plan to install two radar pods (each with its own active array antenna) under the wings of the Global Hawk to enable the generation of precision topographic maps and single pass polarimetric-interferometry (SPI) providing vertical structure of ice and vegetation. Global Hawk's range of 8000 nm will enable regional surveys with far fewer sorties as well as measurements of remote locations without the need for long and complicated deployments. We are also developing P-band polarimetry and Ka-band single-pass interferometry capabilities on UAVSAR by replacing the radar antenna and front-end electronics to operate at these

  10. Electrical Bioimpedance-Controlled Surgical Instrumentation. (United States)

    Brendle, Christian; Rein, Benjamin; Niesche, Annegret; Korff, Alexander; Radermacher, Klaus; Misgeld, Berno; Leonhardt, Steffen


    A bioimpedance-controlled concept for bone cement milling during revision total hip replacement is presented. Normally, the surgeon manually removes bone cement using a hammer and chisel. However, this procedure is relatively rough and unintended harm may occur to tissue at any time. The proposed bioimpedance-controlled surgical instrumentation improves this process because, for example, most risks associated with bone cement removal are avoided. The electrical bioimpedance measurements enable online process-control by using the milling head as both a cutting tool and measurement electrode at the same time. Furthermore, a novel integrated surgical milling tool is introduced, which allows acquisition of electrical bioimpedance data for online control; these data are used as a process variable. Process identification is based on finite element method simulation and on experimental studies with a rapid control prototyping system. The control loop design includes the identified process model, the characterization of noise as being normally distributed and the filtering, which is necessary for sufficient accuracy ( ±0.5 mm). Also, in a comparative study, noise suppression is investigated in silico with a moving average filter and a Kalman filter. Finally, performance analysis shows that the bioimpedance-controlled surgical instrumentation may also performs effectively at a higher feed rate (e.g., 5 mm/s).

  11. COLDEX New Data Acquisition Framework

    CERN Document Server

    Grech, Christian


    COLDEX (COLD bore EXperiment) is an experiment of the TE-VSC group installed in the Super Proton Synchrotron (SPS) which mimics a LHC type cryogenic vacuum system. In the framework of the High Luminosity upgrade of the LHC (HL-LHC project), COLDEX has been recommissioned in 2014 in order to validate carbon coatings performances at cryogenic temperature with LHC type beams. To achieve this mission, a data acquisition system is needed to retrieve and store information from the different experiment’s systems (vacuum, cryogenics, controls, safety) and perform specific calculations. This work aimed to completely redesign, implement, test and operate a brand new data acquisition framework based on communication with the experiment’s PLCs for the devices potentially available over network. The communication protocol to the PLCs is based on data retrieval both from CERN middleware infrastructures (CMW, JAPC) and on a novel open source Simatic S7 data exchange package over TCP/IP (libnodave).

  12. Music and early language acquisition. (United States)

    Brandt, Anthony; Gebrian, Molly; Slevc, L Robert


    Language is typically viewed as fundamental to human intelligence. Music, while recognized as a human universal, is often treated as an ancillary ability - one dependent on or derivative of language. In contrast, we argue that it is more productive from a developmental perspective to describe spoken language as a special type of music. A review of existing studies presents a compelling case that musical hearing and ability is essential to language acquisition. In addition, we challenge the prevailing view that music cognition matures more slowly than language and is more difficult; instead, we argue that music learning matches the speed and effort of language acquisition. We conclude that music merits a central place in our understanding of human development.

  13. Music and Early Language Acquisition

    Directory of Open Access Journals (Sweden)

    Anthony K. Brandt


    Full Text Available Language is typically viewed as fundamental to human intelligence. Music, while recognized as a human universal, is often treated as an ancillary ability—one dependent on or derivative of language. In contrast, we argue that it is more productive from a developmental perspective to describe spoken language as a special type of music. A review of existing studies presents a compelling case that musical hearing and ability is essential to language acquisition. In addition, the authors challenge the prevailing view that music cognition matures more slowly than language and is more difficult; instead, the authors present evidence that music learning matches the speed and effort of language acquisition. We conclude that music merits a central place in our understanding of human development.

  14. The ALICE data acquisition system

    CERN Document Server

    Carena, F; Chapeland, S; Chibante Barroso, V; Costa, F; Dénes, E; Divià, R; Fuchs, U; Grigore, A; Kiss, T; Simonetti, G; Soós, C; Telesca, A; Vande Vyvre, P; Von Haller, B


    In this paper we describe the design, the construction, the commissioning and the operation of the Data Acquisition (DAQ) and Experiment Control Systems (ECS) of the ALICE experiment at the CERN Large Hadron Collider (LHC). The DAQ and the ECS are the systems used respectively for the acquisition of all physics data and for the overall control of the experiment. They are two computing systems made of hundreds of PCs and data storage units interconnected via two networks. The collection of experimental data from the detectors is performed by several hundreds of high-speed optical links. We describe in detail the design considerations for these systems handling the extreme data throughput resulting from central lead ions collisions at LHC energy. The implementation of the resulting requirements into hardware (custom optical links and commercial computing equipment), infrastructure (racks, cooling, power distribution, control room), and software led to many innovative solutions which are described together with ...

  15. Music and Early Language Acquisition (United States)

    Brandt, Anthony; Gebrian, Molly; Slevc, L. Robert


    Language is typically viewed as fundamental to human intelligence. Music, while recognized as a human universal, is often treated as an ancillary ability – one dependent on or derivative of language. In contrast, we argue that it is more productive from a developmental perspective to describe spoken language as a special type of music. A review of existing studies presents a compelling case that musical hearing and ability is essential to language acquisition. In addition, we challenge the prevailing view that music cognition matures more slowly than language and is more difficult; instead, we argue that music learning matches the speed and effort of language acquisition. We conclude that music merits a central place in our understanding of human development. PMID:22973254

  16. Instrumented Pipeline Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Thomas Piro; Michael Ream


    This report summarizes technical progress achieved during the cooperative agreement between Concurrent Technologies Corporation (CTC) and U.S. Department of Energy to address the need for a for low-cost monitoring and inspection sensor system as identified in the Department of Energy (DOE) National Gas Infrastructure Research & Development (R&D) Delivery Reliability Program Roadmap.. The Instrumented Pipeline Initiative (IPI) achieved the objective by researching technologies for the monitoring of pipeline delivery integrity, through a ubiquitous network of sensors and controllers to detect and diagnose incipient defects, leaks, and failures. This report is organized by tasks as detailed in the Statement of Project Objectives (SOPO). The sections all state the objective and approach before detailing results of work.


    Mims, L.S.


    A multi-purpose instrument for measuring neutron flux, coolant flow rate, and coolant temperature in a nuclear reactor is described. The device consists essentially of a hollow thimble containing a heat conducting element protruding from the inner wall, the element containing on its innermost end an amount of fissionsble materinl to function as a heat source when subjected to neutron flux irradiation. Thermocouple type temperature sensing means are placed on the heat conducting element adjacent the fissionable material and at a point spaced therefrom, and at a point on the thimble which is in contact with the coolant fluid. The temperature differentials measured between the thermocouples are determinative of the neutron flux, coolant flow, and temperature being measured. The device may be utilized as a probe or may be incorporated in a reactor core. (AE C)

  18. Astronomical Instrumentation System Markup Language (United States)

    Goldbaum, Jesse M.


    The Astronomical Instrumentation System Markup Language (AISML) is an Extensible Markup Language (XML) based file format for maintaining and exchanging information about astronomical instrumentation. The factors behind the need for an AISML are first discussed followed by the reasons why XML was chosen as the format. Next it's shown how XML also provides the framework for a more precise definition of an astronomical instrument and how these instruments can be combined to form an Astronomical Instrumentation System (AIS). AISML files for several instruments as well as one for a sample AIS are provided. The files demonstrate how AISML can be utilized for various tasks from web page generation and programming interface to instrument maintenance and quality management. The advantages of widespread adoption of AISML are discussed.

  19. Utilizing Information Technology to Facilitate Rapid Acquisition (United States)


    ordering systems to facilitate streamlined commercial item acquisitions that reap the benefits of improved efficiency, reduced overall costs, and...PAGES 109 14. SUBJECT TERMS Rapid Acquisition, eCommerce , eProcurement, Information Technology, Contracting, Global Information Network...streamlined commercial item acquisitions that reap the benefits of improved efficiency, reduced overall costs, and timeliness. This thesis

  20. 32 CFR 644.7 - Acquisition lines. (United States)


    ... HANDBOOK Project Planning Civil Works § 644.7 Acquisition lines. (a) Tentative acquisition lines. As..., in accordance with sound real estate practices. Accordingly, fringe tracts will not be acquired until the final acquisition lines are approved by the Division Engineer. (b) Submission. As soon as possible...

  1. Sustaining an Acquisition-based Growth Strategy

    DEFF Research Database (Denmark)

    Henningsson, Stefan; Toppenberg, Gustav; Shanks, Graeme

    Value creating acquisitions are a major challenge for many firms. Our case study of Cisco Systems shows that an advanced Enterprise Architecture (EA) capability can contribute to the acquisition process through a) preparing the acquirer to become ‘acquisition ready’, b) identifying resource......-based growth strategy over time....

  2. The acquisition of speech and language. (United States)

    Woodfield, T A


    There are many theories behind speech and language acquisition. The role of parents in social interaction with their infant to facilitate speech and language acquisition is of paramount importance. Several pathological influences may hinder speech and language acquisition. Children's nurses need knowledge and understanding of how speech and language are acquired.

  3. Managing IT Integration Risk in Acquisitions

    DEFF Research Database (Denmark)

    Henningsson, Stefan; Kettinger, William J.


    The article discusses a framework for evaluating risk of information technology (IT) integration in acquisitions. Topics include the use of the experience of serial acquirer Trelleborg AB to show the merits of the framework for managing the risk and to determine low-risk acquisitions......, the importance of managing IT integration risk, and various risk areas for acquisition IT integration....

  4. Acquisition of HPLC-Mass Spectrometer (United States)


    31-Jan-2015 Approved for Public Release; Distribution Unlimited Final Report: Acquisition of HPLC -Mass Spectrometer The views, opinions and/or findings...published in peer-reviewed journals: Final Report: Acquisition of HPLC -Mass Spectrometer Report Title The acquisition of the mass spectrometer has been a

  5. Including secondary illumination in seismic acquisition design

    NARCIS (Netherlands)

    Kumar, A.; Blacquière, G.


    A subsurface image obtained from seismic data is influenced by the acquisition geometry, as it contains an acquisition foot-print which can obscure the true reflection response of the subsurface. Hence, the acquisition geometry should be designed in such a way that it allows high-quality images and

  6. Information Acquisition, Analysis and Integration (United States)


    Deep neural networks with random Gaussian weights: A universal classification strategy?,” IEEE Trans. Signal Processing, 2016, to appear. 2. M. applications, new camera designs, and numerous DoD and industrial technology transfers. 15. SUBJECT TERMS Information acquisition, integration...Defense (ONR, ARO, NGA), to the NIH, and to industry (Adobe, LSS, etc). As mentioned above, these also resulted in numerous awards and become the core

  7. Aerial robotic data acquisition system

    Energy Technology Data Exchange (ETDEWEB)

    Hofstetter, K.J.; Hayes, D.W.; Pendergast, M.M. [Westinghouse Savannah River Co., Aiken, SC (United States); Corban, J.E. [Guided Systems Technologies, Atlanta, GA (United States)


    A small, unmanned aerial vehicle (UAV), equipped with sensors for physical and chemical measurements of remote environments, is described. A miniature helicopter airframe is used as a platform for sensor testing and development. The sensor output is integrated with the flight control system for real-time, interactive, data acquisition and analysis. Pre-programmed flight missions will be flown with several sensors to demonstrate the cost-effective surveillance capabilities of this new technology.

  8. The Cybersecurity Challenge in Acquisition (United States)


    modern supply chain will add vulnerabilities to these linked supplier systems. Introduction Cyber Threat Challenges The accelerated growth in cyber...cyber challenges of their systems at the right level of detail is the only viable solution to this problem in the long run. Securing Supply Chains turn introduce new vulnerabilities in the organization and must be managed by those acquisition specialists focused most on the supply chain

  9. Complex System Governance for Acquisition (United States)


    indicate a similar meaning for governance as the CSG meaning? and (3) Is there any concrete indication that the tools and methods of CSG would have...formulation of the structure and execution of a system (e.g., acquisition program). This structure and its execution ultimately determine the level...missing cost, schedule, performance expectations). Instead, more fundamental systems based pathologies (i.e., aberrations from healthy system conditions

  10. A review of spelling acquisition

    DEFF Research Database (Denmark)

    Dich, Nadya; Cohn, Abigail C.


    This review article discusses how empirical data on the acquisition of spelling by children inform the question of the psycholinguistic validity of the phoneme, a concept central (at least implicitly) to most phonological theories. The paper reviews data on children's early spelling attempts...... is offered suggesting that orthographic and phonological knowledge develop together into a hierarchy of representations. While the idea of multidimensional phonological representations has been previously entertained in psycholinguistic literature, none of the previous proposals has explicitly incorporated...

  11. Fast Access Data Acquisition System

    Energy Technology Data Exchange (ETDEWEB)

    Dr. Vladimir Katsman


    Our goal in this program is to develop Fast Access Data Acquisition System (FADAS) by combining the flexibility of Multilink's GaAs and InP electronics and electro-optics with an extremely high data rate for the efficient handling and transfer of collider experimental data. This novel solution is based on Multilink's and Los Alamos National Laboratory's (LANL) unique components and technologies for extremely fast data transfer, storage, and processing.

  12. Data acquisition for sensor systems

    CERN Document Server

    Taylor, H Rosemary


    'Data acquisition' is concerned with taking one or more analogue signals and converting them to digital form with sufficient accu­ racy and speed to be ready for processing by a computer. The increasing use of computers makes this an expanding field, and it is important that the conversion process is done correctly because information lost at this stage can never be regained, no matter how good the computation. The old saying - garbage in, garbage out - is very relevant to data acquisition, and so every part of the book contains a discussion of errors: where do they come from, how large are they, and what can be done to reduce them? The book aims to treat the data acquisition process in depth with less detailed chapters on the fundamental principles of measure­ ment, sensors and signal conditioning. There is also a chapter on software packages, which are becoming increasingly popular. This is such a rapidly changing topic that any review of available pro­ grams is bound to be out of date before the book re...

  13. 75 FR 77745 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-47; Small Entity Compliance Guide (United States)


    ... Acquisition Regulation; Federal Acquisition Circular 2005-47; Small Entity Compliance Guide AGENCIES... a summary of rules appearing in Federal Acquisition Circular (FAC) 2005-47, which amend the FAR. An... 17.5 now addresses all interagency acquisitions, not just those made under the Economy Act authority...

  14. 76 FR 68044 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-54; Small Entity Compliance Guide (United States)


    ... Acquisition Regulation; Federal Acquisition Circular 2005-54; Small Entity Compliance Guide AGENCY: Department... rules appearing in Federal Acquisition Circular (FAC) 2005-54, which amend the Federal Acquisition... (FAR Case 2009-006) This final rule amends the FAR to implement Executive Order (E.O.) 13494, Economy...

  15. 76 FR 68013 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-54; Introduction (United States)


    ... Space Administration 48 CFR Part 1 Federal Acquisition Regulation; Federal Acquisition Circular 2005-54... Acquisition Circular 2005-54; Introduction AGENCIES: Department of Defense (DoD), General Services...) rules agreed to by DoD, GSA, and NASA in this Federal Acquisition Circular (FAC) 2005-54. A companion...

  16. Interstate-35 bridge instrumentation renaissance. (United States)


    An updated, accelerometer-based, sensor and data acquisition system was installed and verified on the I-35 Walnut Creek Bridge in Purcell, Oklahoma. The data collection system also includes a microwave communication system to move sensor and video da...

  17. The role of the anterior, mediodorsal, and parafascicular thalamus in instrumental conditioning. (United States)

    Bradfield, Laura A; Hart, Genevra; Balleine, Bernard W


    The traditional animal model of instrumental behavior has focused almost exclusively on structures within the cortico-striatal network and ignored the contributions of various thalamic nuclei despite large and specific connections with each of these structures. One possible reason for this is that the thalamus has been conventionally viewed as a mediator of general processes, such as attention, arousal and movement, that are not easily separated from more cognitive aspects of instrumental behavior. Recent research has, however, begun to separate these roles. Here we review the role of three thalamic nuclei in instrumental conditioning: the anterior thalamic nuclei (ANT), the mediodorsal (MD), and parafascicular thalamic nuclei (PF). Early research suggested that ANT might regulate aspects of instrumental behavior but, on review, we suggest that the types of tasks used in these studies were more likely to recruit Pavlovian processes. Indeed lesions of ANT have been found to have no effect on performance in instrumental free-operant tasks. By contrast the mediodorsal thalamus (MD) has been found to play a specific and important role in the acquisition of goal-directed action. We propose this role is related to its connections with prelimbic cortex (PL) and present new data that directly implicates this circuit in the acquisition of goal-directed actions. Finally we review evidence suggesting the PF, although not critical for the acquisition or performance of instrumental actions, plays a specific role in regulating action flexibility.

  18. The role of the anterior, mediodorsal, and parafascicular thalamus in instrumental conditioning

    Directory of Open Access Journals (Sweden)

    Laura Anne Bradfield


    Full Text Available The traditional animal model of instrumental behaviour has focused almost exclusively on structures within the cortico-striatal network and ignored the contributions of various thalamic nuclei despite large and specific connections with each of these structures. One possible reason for this is that the thalamus has been conventionally viewed as a mediator of general processes, such as attention, arousal and movement, that are not easily separated from more cognitive aspects of instrumental behaviour. Recent research has, however, begun to separate these roles. Here we review the role of three thalamic nuclei in instrumental conditioning: the anterior, the mediodorsal, and parafascicular thalamic nuclei. Early research suggested that anterior thalamic nuclei might regulate aspects of instrumental behaviour but, on review, we suggest that the types of tasks used in these studies were more likely to recruit Pavlovian processes. Indeed lesions of anterior thalamic nuclei have been found to have no effect on performance in instrumental free-operant tasks. By contrast the mediodorsal thalamus has been found to play a specific and important role in the acquisition of goal-directed action. We propose this role is related to its connections with prelimbic cortex and present new data that directly implicates this circuit in the acquisition of goal-directed actions. Finally we review evidence suggesting the parafascicular thalamic nucleus, although not critical for the acquisition or performance of instrumental actions, plays a specific role in regulating action flexibility.

  19. Instrumental Variable Estimation with Heteroskedasticity and Many Instruments


    Jerry A. Hausman; Newey, Whitney K.; Woutersen, Tiemen; Chao, John; Swanson, Norman


    This paper gives a relatively simple, well behaved solution to the problem of many instruments in heteroskedastic data. Such settings are common in microeconometric applications where many instruments are used to improve efficiency and allowance for heteroskedasticity is generally important. The solution is a Fuller (1977) like estimator and standard errors that are robust to heteroskedasticity and many instruments. We show that the estimator has finite moments and high asymptotic efficiency ...

  20. Pancreatitis Quality of Life Instrument: Development of a new instrument

    Directory of Open Access Journals (Sweden)

    Wahid Wassef


    Full Text Available Objectives: The goal of this project was to develop the first disease-specific instrument for the evaluation of quality of life in chronic pancreatitis. Methods: Focus groups and interview sessions were conducted, with chronic pancreatitis patients, to identify items felt to impact quality of life which were subsequently formatted into a paper-and-pencil instrument. This instrument was used to conduct an online survey by an expert panel of pancreatologists to evaluate its content validity. Finally, the modified instrument was presented to patients during precognitive testing interviews to evaluate its clarity and appropriateness. Results: In total, 10 patients were enrolled in the focus groups and interview sessions where they identified 50 items. Once redundant items were removed, the 40 remaining items were made into a paper-and-pencil instrument referred to as the Pancreatitis Quality of Life Instrument. Through the processes of content validation and precognitive testing, the number of items in the instrument was reduced to 24. Conclusions: This marks the development of the first disease-specific instrument to evaluate quality of life in chronic pancreatitis. It includes unique features not found in generic instruments (economic factors, stigma, and spiritual factors. Although this marks a giant step forward, psychometric evaluation is still needed prior to its clinical use.

  1. Pancreatitis Quality of Life Instrument: Development of a new instrument. (United States)

    Wassef, Wahid; Bova, Carol; Barton, Bruce; Hartigan, Celia


    The goal of this project was to develop the first disease-specific instrument for the evaluation of quality of life in chronic pancreatitis. Focus groups and interview sessions were conducted, with chronic pancreatitis patients, to identify items felt to impact quality of life which were subsequently formatted into a paper-and-pencil instrument. This instrument was used to conduct an online survey by an expert panel of pancreatologists to evaluate its content validity. Finally, the modified instrument was presented to patients during precognitive testing interviews to evaluate its clarity and appropriateness. In total, 10 patients were enrolled in the focus groups and interview sessions where they identified 50 items. Once redundant items were removed, the 40 remaining items were made into a paper-and-pencil instrument referred to as the Pancreatitis Quality of Life Instrument. Through the processes of content validation and precognitive testing, the number of items in the instrument was reduced to 24. This marks the development of the first disease-specific instrument to evaluate quality of life in chronic pancreatitis. It includes unique features not found in generic instruments (economic factors, stigma, and spiritual factors). Although this marks a giant step forward, psychometric evaluation is still needed prior to its clinical use.

  2. Acquisition system for the CLIC Module

    CERN Document Server

    Vilalte, Sebastien


    The status of R&D activities for CLIC module acquisition are discussed [1]. LAPP is involved in the design of the local CLIC module acquisition crate, described in the document Study of the CLIC Module Front-End Acquisition and Evaluation Electronics [2]. This acquisition system is a project based on a local crate, assigned to the CLIC module, including several mother boards. These motherboards are foreseen to hold mezzanines dedicated to the different subsystems. This system has to work in radiation environment. LAPP is involved in the development of Drive Beam stripline position monitors read-out, described in the document Drive Beam Stripline BPM Electronics and Acquisition [3]. LAPP also develops a generic acquisition mezzanine that allows to perform all-around acquisition and components tests for drive beam stripline BPM read-out.

  3. Acquisitions by EMNCs in Developed Markets

    DEFF Research Database (Denmark)

    Rabbiosi, Larissa; Elia, Stefano; Bertoni, Fabio


    Building on an organisational learning perspective, we argue that emerging market firms’ international experience and home-country characteristics are core sources of learning. Furthermore, we argue that these factors constitute important determinants of emerging market firms’ acquisition behaviour...... in developed countries (south-north acquisitions). We test our hypotheses on a sample of 808 south-north acquisitions. The acquisitions were undertaken in Europe, Japan and North America (Canada and the US) between 1999 and 2008 by firms from the emerging economies of Brazil, Russia, India and China....... As suggested by the internationalisation process model, our results show that emerging market firms undertake acquisitions in developed countries in an incremental fashion. Acquisition experience in developed markets increases the likelihood of exploitative expansion, while acquisition experience in developing...

  4. Improving Acquisition Outcomes with Contextual Ambidexterity

    DEFF Research Database (Denmark)

    Meglio, Olimpia; King, David R.; Risberg, Annette


    The results of research on mergers and acquisitions often point to a need to improve acquisition outcomes and lessen the organizational turmoil that can often follow integration efforts. We assert that viewing acquisition integration through the lens of contextual ambidexterity may improve...... acquisition outcomes in two ways: by providing an integrated solution to the economic and social tensions in acquisitions, and by enabling managers to effectively confront the competing needs of task and human integration. We also posit that by building on contextual ambidexterity, we can extend...... the possibilities for both research and practice regarding task and human integration in acquisitions. We also emphasize the role of an integration manager and integration mechanisms in enabling contextual ambidexterity for successful acquisition integration. Finally, we identify implications for research...

  5. Spent fuel test. Climax data acquisition system integration report

    Energy Technology Data Exchange (ETDEWEB)

    Nyholm, R.A.; Brough, W.G.; Rector, N.L.


    The Spent Fuel Test - Climax (SFT-C) is a test of the retrievable, deep geologic storage of commercially generated, spent nuclear reactor fuel in granitic rock. Eleven spent fuel assemblies, together with 6 electrical simulators and 20 guard heaters, are emplaced 420 m below the surface in the Climax granite at the Nevada Test Site. On June 2, 1978, Lawrence Livermore National Laboratory (LLNL) secured funding for the SFT-C, and completed spent fuel emplacement May 28, 1980. This multi-year duration test is located in a remote area and is unattended much of the time. An extensive array of radiological safety and geotechnical instrumentation is deployed to monitor the test performance. A dual minicomputer-based data acquisition system collects and processes data from more than 900 analog instruments. This report documents the design and functions of the hardware and software elements of the Data Acquisition System and describes the supporting facilities which include environmental enclosures, heating/air-conditioning/humidity systems, power distribution systems, fire suppression systems, remote terminal stations, telephone/modem communications, and workshop areas. 9 figures.

  6. Behavioural Motives of Acquisition of Solar-driven Equipment

    Directory of Open Access Journals (Sweden)

    Shkurupska Iryna O.


    Full Text Available The article identifies needs of the target group, namely structure of motives, which justify making a decision to buy, in order to create efficient marketing strategy of an enterprise, which sell solar-driven equipment in Ukraine. There are five segments in the domestic market of helio-systems: individual consumers, recreation industry, agrarian industry, construction and social spheres. The article allocates 15 motives of acquisition of the solar-driven equipment for these segments, the most important of which are price, availability of solar energy, alternative price and energy saving. Besides, the structure of such motives is determined for each segment individually. In order to choose specific marketing instruments in the policy of promotion of solar-driven equipment, the article identifies differences in the form of goals of use and motives of acquisition between the specified consumer segments. The article reveals certain barriers that interfere with acquisition of solar-driven equipment – low level of trust into helio-systems, conservatism of consumers, absence of free applications for consumers – overcoming which is only possible with the help of certain marketing actions.

  7. Goddard Space Flight Center's Structural Dynamics Data Acquisition System (United States)

    McLeod, Christopher


    Turnkey Commercial Off The Shelf (COTS) data acquisition systems typically perform well and meet most of the objectives of the manufacturer. The problem is that they seldom meet most of the objectives of the end user. The analysis software, if any, is unlikely to be tailored to the end users specific application; and there is seldom the chance of incorporating preferred algorithms to solve unique problems. Purchasing a customized system allows the end user to get a system tailored to the actual application, but the cost can be prohibitive. Once the system has been accepted, future changes come with a cost and response time that's often not workable. When it came time to replace the primary digital data acquisition system used in the Goddard Space Flight Center's Structural Dynamics Test Section, the decision was made to use a combination of COTS hardware and in-house developed software. The COTS hardware used is the DataMAX II Instrumentation Recorder built by R.C. Electronics Inc. and a desktop Pentium 4 computer system. The in-house software was developed using MATLAF3 from The Mathworks. This paper will describe the design and development of the new data acquisition and analysis system.

  8. Side-by side intercomparison between two TCCON instruments (United States)

    Feist, Dietrich G.; Griffith, David W. T.; Velazco, Voltaire A.; Deutscher, Nicholas M.


    The Total Carbon Colummn Observing Network (TCCON) observes column-averaged dry-air mole fractions of CO2, CH4, CO, N2O, and other trace gases at more than 20 stations worldwide. These measurements are the calibration basis for all current and many future satellite greenhouse-gas-observing missions. TCCON's goal is to provide the most precise and accurate data with uncertainties better than 0.25%. Especially inter-station biases in the network are critical and should be reduced to a minimum. TCCON uses Fourier Transform Spectrometers (FTS) which are comparatively large and expensive instruments that are not easily moved around. In the network, the typical distance between TCCON stations is hundreds to thousands of kilometers. Therefore, opportunities to directly compare the performance of TCCON instruments are very rare. In 2010, the TCCON instrument from the Max Planck Institute for Biogeochemistry (MPI-BGC) in Jena, Germany, was set up close to a TCCON instrument at the University of Wollongong, Wollongong, Australia, for six months. This was part of a test campaign before the final deployment of the MPI-BGC instrument to Ascension Island. Due to problems with the acquisition and processing of TCCON data at the time, the results of the intercomparison were inconclusive at first. Spectroscopic artifacts known as ghosts affected TCCON data until 2011. The ghosts created relatively large biases between individual instruments that were in the range of TCCON's precision and accuracy goals. The ghost problem was fixed by a hardware upgrade for all TCCON instruments in 2011 but still remained in older data. Only with the latest TCCON processing software GGG2014, the ghosts could finally be removed from the pre-2011 TCCON data. Therefore, a detailed side-by-side intercomparison between the two TCCON instruments at Wollongong in 2010 has now become possible.

  9. Impact Disdrometers Instrument Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Bartholomew, Mary Jane [Brookhaven National Lab. (BNL), Upton, NY (United States)


    To improve the quantitative description of precipitation processes in climate models, the U.S. Department of Energy’s Atmospheric Radiation Measurement (ARM) Climate Research Facility has been collecting observations of the drop size spectra of rain events since early in 2006. Impact disdrometers were the initial choice due to their reliability, ease of maintenance, and relatively low cost. Each of the two units deployed was accompanied by a nearby tipping bucket. In 2010, the tipping buckets were replaced by weighing buckets rain gauges. Five video disdrometers were subsequently purchased and are described in ARM’s VDIS Handbook.1 As of April 2011, three of the weighing bucket instruments were deployed, one was to travel with the second ARM Mobile Facility, and the fifth was a spare. Two of the video disdrometers were deployed, a third was to be deployed later in the spring of 2011, one was to travel with the second ARM Mobile Facility, and the last was a spare. Detailed descriptions of impact disdrometers and their datastreams are provided in this document.

  10. Industrial instrumentation principles and design

    CERN Document Server

    Padmanabhan, Tattamangalam R


    Pneumatic, hydraulic and allied instrumentation schemes have given way to electronic schemes in recent years thanks to the rapid strides in electronics and allied areas. Principles, design and applications of such state-of-the-art instrumentation schemes form the subject matter of this book. Through representative examples, the basic building blocks of instrumentation schemes are identified and each of these building blocks discussed in terms of its design and interface characteristics. The common generic schemes synthesized with such building blocks are dealt with subsequently. This forms the scope of Part I. The focus in Part II is on application. Displacement and allied instrumentation, force and allied instrumentation and process instrumentation in terms of temperature, flow, pressure level and other common process variables are dealt with separately and exhaustively. Despite the diversity in the sensor principles and characteristics and the variety in the applications and their environments, it is possib...

  11. Instruments to assess integrated care

    DEFF Research Database (Denmark)

    Lyngsø, Anne Marie; Godtfredsen, Nina Skavlan; Høst, Dorte


    INTRODUCTION: Although several measurement instruments have been developed to measure the level of integrated health care delivery, no standardised, validated instrument exists covering all aspects of integrated care. The purpose of this review is to identify the instruments concerning how...... to measure the level of integration across health-care sectors and to assess and evaluate the organisational elements within the instruments identified. METHODS: An extensive, systematic literature review in PubMed, CINAHL, PsycINFO, Cochrane Library, Web of Science for the years 1980-2011. Selected...... abstracts were independently reviewed by two investigators. RESULTS: We identified 23 measurement instruments and, within these, eight organisational elements were found. No measurement instrument covered all organisational elements, but almost all studies include well-defined structural and process aspects...

  12. Advancements in Actuated Musical Instruments

    DEFF Research Database (Denmark)

    Overholt, Daniel; Berdahl, Edgar; Hamilton, Robert


    This article presents recent developments in actuated musical instruments created by the authors, who also describe an ecosystemic model of actuated performance activities that blur traditional boundaries between the physical and virtual elements of musical interfaces. Actuated musical instruments...... are physical instruments that have been endowed with virtual qualities controlled by a computer in real-time but which are nevertheless tangible. These instruments provide intuitive and engaging new forms of interaction. They are different from traditional (acoustic) and fully automated (robotic) instruments...... in that they produce sound via vibrating element(s) that are co-manipulated by humans and electromechanical systems. We examine the possibilities that arise when such instruments are played in different performative environments and music-making scenarios, and we postulate that such designs may give rise to new...

  13. Acquisition Cost/Price Estimating (United States)



  14. Instrumentation in Frontal Sinus Surgery. (United States)

    Tajudeen, Bobby A; Adappa, Nithin D


    Frontal recess dissection proposes many challenges to the surgeon. These challenges stem from its highly variable nature, small caliber, difficult visualization, and proximity to vital structures such as the skull base and orbit. As such, delicate mucosal-sparing dissection of the frontal recess with proper instrumentation is paramount to minimize scar formation and ensure patency. Here, the article explores key instrumentation in frontal recess surgery with an emphasis on hand instruments and adjunctive technologies. Copyright © 2016 Elsevier Inc. All rights reserved.


    Energy Technology Data Exchange (ETDEWEB)

    Richard Weber, Christopher Benmore


    This Phase II research project was focused on constructing and testing a facility for the measurement of the structure of hot solid and liquid materials under extreme conditions using neutron diffraction. The work resulted in measurements at temperatures of 3300 K, the highest ever performed in a neutron beam. Work was performed jointly by Containerless Research, Inc. and Argonne National Laboratory with significant interactions with engineers and scientists at the under construction-SNS facility in Oak Ridge, TN. The work comprised four main activities: Design and construct an advanced instrument for structural studies of liquids and hot solids using neutron scattering. Develop and test a software package for instrument control, data acquisition and analysis. Test and demonstrate the instrument in experiments at the GLAD beamline at IPNS. Evaluate requirements for performing experiments at the SNS. Develop interest from the potential user base and identify potential support for Phase III. The objectives of the research were met. A second-generation instrument was developed and constructed. The instrument design drew on the results of a formal design review which was held at Argonne National Laboratory during the Phase I research [1]. The review included discussion with potential instrument users, SNS scientists and engineers and various scientists involved with materials, glass, ceramics, and geological sciences. The instrument combines aerodynamic levitation with pulsed neutron diffraction in a controlled atmosphere. An important innovation was the use of pure vanadium levitation nozzles that effectively eliminated contributions from the sample environment to the measured data. The instrument employed a 250 Watt CO2 laser that was configured for Class I laser operation. The use of Class I laser configuration meant that operators could work with the equipment with minimal restrictions and so concentrate on the research activities. Instrument control and data

  16. HAB Buoy: a new instrument for in situ monitoring and early warning ...

    African Journals Online (AJOL)

    A new microplankton imaging and analysis instrument, HAB Buoy, is described. It integrates a high-speed camera for in-flow image acquisition with automatic specimen labelling software, known as DiCANN (Dinoflagellate Categorisation by Artificial Neural Network). Some preliminary results are presented together with a ...

  17. Essays on mergers and acquisitions


    Faelten, A.I.


    “Essays on Mergers and Acquisitions" tackles some of the most prominent business challenges related to M&A activity. The Introduction examines the reasons why deals fail through well-known case studies; Chapter 1 presents a new index measuring countries M&A maturity worldwide; Chapter 2 focus on the importance of corporate governance when conducting deals in unknown territories; whilst Chapter 3 and 4 conduct research on companies’ decision to tap capital markets and their subsequent M&A acti...

  18. Software Switching for Data Acquisition

    CERN Multimedia

    CERN. Geneva; Malone, David


    In this talk we discuss the feasibility of replacing telecom-class routers with a topology of commodity servers acting as software switches in data acquisition. We extend the popular software switch, Open vSwitch, with a dedicated, throughput-oriented buffering mechanism. We compare the performance under heavy many-to-one congestion to typical Ethernet switches and evaluate the scalability when building larger topologies, exploiting the integration with software-defined networking technologies. Please note that David Malone will speak on behalf of Grzegorz Jereczek.

  19. The GRIFFIN data acquisition system (United States)

    Garnsworthy, A. B.; Pearson, C. J.; Bishop, D.; Shaw, B.; Smith, J. K.; Bowry, M.; Bildstein, V.; Hackman, G.; Garrett, P. E.; Linn, Y.; Martin, J.-P.; Mills, W. J.; Svensson, C. E.


    Gamma-Ray Infrastructure For Fundamental Investigations of Nuclei, GRIFFIN, is a new experimental facility for radioactive decay studies at the TRIUMF-ISAC laboratory. This article describes the details of the custom designed GRIFFIN digital data acquisition system. The features of the system that will enable high-precision half-life and branching ratio measurements with levels of uncertainty better than 0.05% are described. The system has demonstrated the ability to effectively collect signals from High-purity germanium crystals at counting rates up to 50 kHz while maintaining good energy resolution, detection efficiency and spectral quality.

  20. Employment effects of foreign acquisition

    DEFF Research Database (Denmark)

    Bandick, Roger; Karpaty, Patrik


    This paper investigates the employment effects of foreign acquisitions in acquired firms in Swedish manufacturing during the 1990s; a period characterized by a dramatic increase in foreign ownership. We find some evidence of positive employment effects in acquired firms and it seems...... that the employment of skilled labor increasesmore than that of less-skilled labor. Our results indicate that the positive employment effects are more pronounced in acquired non-MNEs than in Swedish MNEs. Furthermore, we observe shifts in skill intensities toward higher shares of skilled labor in non-MNEs taken over...

  1. Negotiating optimum capital equipment acquisitions. (United States)

    Pols, A L


    Healthcare organizations planning capital equipment acquisitions should negotiate with more than one equipment vendor and determine the equipment purchase price, service agreement price, and financing or leasing option rate separately to avoid hidden costs. The purchase price should be negotiated first. A long-term service agreement should be locked in, or service insurance purchased, for the length of the financing or lease agreement. The equipment vendor's financing agreement should be compared with offers from third parties, who may have more beneficial financing options or more flexible lease arrangements.

  2. Where are my instruments? Hazards in delivery of surgical instruments

    NARCIS (Netherlands)

    Guédon, A.C.P.; Wauben, L.S.G.L.; Van der Eijk, A.C.; Vernooij, A.S.N.; Meeuwsen, F.C.; Van der Elst, M.; Hoeijmans, V.; Dankelman, J.; Van den Dobbelsteen, J.J.


    Background Unavailability of instruments is recognised to cause delays and stress in the operating room, which can lead to additional risks for the patients. The aim was to provide an overview of the hazards in the entire delivery process of surgical instruments and to provide insight into how

  3. Kinetics Analysis of Respiratory Epithelium by Virtual Instrumentation

    Directory of Open Access Journals (Sweden)

    Libor HARGAŠ


    Full Text Available The article deals with measurement and analysis of kinetic parameters of human respiratory epithelium. The article shows possibilities of data acquisition (videosequences and postprocessing using virtual instrumentation – LabVIEW. The designed methods enable analysis and measurement of two parameters: cilia beat frequency (CBF and trajectory of cilia of respiratory epithelium. The problem task is divided into videosequence acquisition of cilia from the microscope, region of interest (ROI selection for analyzed data reduction, preprocessing of reduced sequences. Frequency analysis is done by intensity method, which records and evaluates intensity variations in ROI. Trajectory analysis uses sophisticated algorithms of object detection in the image called pattern matching. Results of this work are used for diagnostics of some pathology of respiratory apparatus and epithelium. All solution steps are realized in LabVIEW development system.

  4. [Photoelectric parametric test system of LED based on virtual instrument]. (United States)

    Yang, Song-Tao; Wang, Jing; Wang, Li-Dong; Liang, Pei; Dong, Qian-Min


    The standardized measuring principle, requirements and implementations of the above parameters of LEDs were researched and analyzed in the present paper. Then a comprehensive test system involved with optics, machinery and computer was designed to accomplish data acquisition, algorithm design and interface design on virtual instrument using NI data acquisition card USB6210. And convincing results of LEDs' parameters, including peak wavelength, width of half-peak wavelength, centroid wavelength, chromaticity coordinates, purity, correlated color temperature and the forward voltage/current, were achieved with good consistency based on the measured spectrum. The system owns simple interface, reliable algorithms and stable results. Respective measurements on five kinds of color of LED result in an average error less than 3%, which show an ideal performance of the system.

  5. MISR Instrument Data Visualization (United States)

    Nelson, David; Garay, Michael; Diner, David; Thompson, Charles; Hall, Jeffrey; Rheingans, Brian; Mazzoni, Dominic


    The MISR Interactive eXplorer (MINX) software functions both as a general-purpose tool to visualize Multiangle Imaging SpectroRadiometer (MISR) instrument data, and as a specialized tool to analyze properties of smoke, dust, and volcanic plumes. It includes high-level options to create map views of MISR orbit locations; scrollable, single-camera RGB (red-greenblue) images of MISR level 1B2 (L1B2) radiance data; and animations of the nine MISR camera images that provide a 3D perspective of the scenes that MISR has acquired. NASA Tech Briefs, September 2008 55 The plume height capability provides an accurate estimate of the injection height of plumes that is needed by air quality and climate modelers. MISR provides global high-quality stereo height information, and this program uses that information to perform detailed height retrievals of aerosol plumes. Users can interactively digitize smoke, dust, or volcanic plumes and automatically retrieve heights and winds, and can also archive MISR albedos and aerosol properties, as well as fire power and brightness temperatures associated with smoke plumes derived from Moderate Resolution Imaging Spectroradiometer (MODIS) data. Some of the specialized options in MINX enable the user to do other tasks. Users can display plots of top-of-atmosphere bidirectional reflectance factors (BRFs) versus camera-angle for selected pixels. Images and animations can be saved to disk in various formats. Also, users can apply a geometric registration correction to warp camera images when the standard processing correction is inadequate. It is possible to difference the images of two MISR orbits that share a path (identical ground track), as well as to construct pseudo-color images by assigning different combinations of MISR channels (angle or spectral band) to the RGB display channels. This software is an interactive application written in IDL and compiled into an IDL Virtual Machine (VM) ".sav" file.

  6. A portable detection instrument based on DSP for beef marbling (United States)

    Zhou, Tong; Peng, Yankun


    Beef marbling is one of the most important indices to assess beef quality. Beef marbling is graded by the measurement of the fat distribution density in the rib-eye region. However quality grades of beef in most of the beef slaughtering houses and businesses depend on trainees using their visual senses or comparing the beef slice to the Chinese standard sample cards. Manual grading demands not only great labor but it also lacks objectivity and accuracy. Aiming at the necessity of beef slaughtering houses and businesses, a beef marbling detection instrument was designed. The instrument employs Charge-coupled Device (CCD) imaging techniques, digital image processing, Digital Signal Processor (DSP) control and processing techniques and Liquid Crystal Display (LCD) screen display techniques. The TMS320DM642 digital signal processor of Texas Instruments (TI) is the core that combines high-speed data processing capabilities and real-time processing features. All processes such as image acquisition, data transmission, image processing algorithms and display were implemented on this instrument for a quick, efficient, and non-invasive detection of beef marbling. Structure of the system, working principle, hardware and software are introduced in detail. The device is compact and easy to transport. The instrument can determine the grade of beef marbling reliably and correctly.

  7. Theories of early language acquisition. (United States)

    Plunkett, K


    What features of brain processing and neural development support linguistic development in young children? To what extent is the profile and timing of linguistic development in young children determined by a pre-ordained genetic programme? Does the environment play a crucial role in determining the patterns of change observed in children growing up? Recent experimental, neuroimaging and computational studies of developmental change in children promise to contribute to a deeper understanding of how the brain becomes wired up for language. In this review, the muttidisciplinary perspectives of cognitive neuroscience, experimental psycholinguistics and neural network modelling are brought to bear on four distinct areas in the study of language acquisition: early speech perception, word recognition, word learning and the acquisition of grammatical inflections. It is suggested that each area demonstrates how linguistic development can be driven by the interaction of general learning mechanisms, highly sensitive to particular statistical regularities in the input, with a richly structured environment which provides the necessary ingredients for the emergence of linguistic representations that support mature language processing. Similar epigenetic principles, guiding the emergence of linguistic structure, apply to all these domains, offering insights into phenomena ranging from the precocity of young infant's sensitivity to speech contrasts to the complexities of the problem facing the young child learning the arabic plural.

  8. Rotary Percussive Sample Acquisition Tool (United States)

    Klein, K.; Badescu, M.; Haddad, N.; Shiraishi, L.; Walkemeyer, P.


    As part of a potential Mars Sample Return campaign NASA is studying a sample caching mission to Mars, with a possible 2018 launch opportunity. As such, a Sample Acquisition Tool (SAT) has been developed in support of the Integrated Mars Sample Acquisition and Handling (IMSAH) architecture as it relates to the proposed Mars Sample Return (MSR) campaign. The tool allows for core generation and capture directly into a sample tube. In doing so, the sample tube becomes the fundamental handling element within the IMSAH sample chain reducing the risk associated with sample contamination as well as the need to handle a sample of unknown geometry. The tool's functionality was verified utilizing a proposed rock test suite that encompasses a series of rock types that have been utilized in the past to qualify Martian surface sampling hardware. The corresponding results have shown the tool can effectively generate, fracture, and capture rock cores while maintaining torque margins of no less than 50% with an average power consumption of no greater than 90W and a tool mass of less than 6kg.

  9. CARMENES instrument control system and operational scheduler (United States)

    Garcia-Piquer, Alvaro; Guàrdia, Josep; Colomé, Josep; Ribas, Ignasi; Gesa, Lluis; Morales, Juan Carlos; Pérez-Calpena, Ana; Seifert, Walter; Quirrenbach, Andreas; Amado, Pedro J.; Caballero, José A.; Reiners, Ansgar


    The main goal of the CARMENES instrument is to perform high-accuracy measurements of stellar radial velocities (1m/s) with long-term stability. CARMENES will be installed in 2015 at the 3.5 m telescope in the Calar Alto Observatory (Spain) and it will be equipped with two spectrographs covering from the visible to the near-infrared. It will make use of its near-IR capabilities to observe late-type stars, whose peak of the spectral energy distribution falls in the relevant wavelength interval. The technology needed to develop this instrument represents a challenge at all levels. We present two software packages that play a key role in the control layer for an efficient operation of the instrument: the Instrument Control System (ICS) and the Operational Scheduler. The coordination and management of CARMENES is handled by the ICS, which is responsible for carrying out the operations of the different subsystems providing a tool to operate the instrument in an integrated manner from low to high user interaction level. The ICS interacts with the following subsystems: the near-IR and visible channels, composed by the detectors and exposure meters; the calibration units; the environment sensors; the front-end electronics; the acquisition and guiding module; the interfaces with telescope and dome; and, finally, the software subsystems for operational scheduling of tasks, data processing, and data archiving. We describe the ICS software design, which implements the CARMENES operational design and is planned to be integrated in the instrument by the end of 2014. The CARMENES operational scheduler is the second key element in the control layer described in this contribution. It is the main actor in the translation of the survey strategy into a detailed schedule for the achievement of the optimization goals. The scheduler is based on Artificial Intelligence techniques and computes the survey planning by combining the static constraints that are known a priori (i.e., target

  10. 14 CFR 27.1337 - Powerplant instruments. (United States)


    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Powerplant instruments. 27.1337 Section 27... AIRWORTHINESS STANDARDS: NORMAL CATEGORY ROTORCRAFT Equipment Instruments: Installation § 27.1337 Powerplant instruments. (a) Instruments and instrument lines. (1) Each powerplant instrument line must meet the...

  11. 14 CFR 29.1337 - Powerplant instruments. (United States)


    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Powerplant instruments. 29.1337 Section 29... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Instruments: Installation § 29.1337 Powerplant instruments. (a) Instruments and instrument lines. (1) Each powerplant and auxiliary power unit instrument...

  12. 14 CFR 25.1337 - Powerplant instruments. (United States)


    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Powerplant instruments. 25.1337 Section 25... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Instruments: Installation § 25.1337 Powerplant instruments. (a) Instruments and instrument lines. (1) Each powerplant and auxiliary power unit instrument...

  13. Technician Program Uses Advanced Instruments. (United States)

    Stinson, Stephen


    Describes various aspects of a newly-developed computer-assisted drafting/computer-assisted manufacture (CAD/CAM) facility in the chemical engineering technology department at Broome Community College, Binghamton, New York. Stresses the use of new instruments such as microcomputers and microprocessor-equipped instruments. (CS)

  14. Zach's instruments and their characteristics (United States)

    Wolfschmidt, Gudrun

    The astronomically interested Duke Ernst II von Sachsen-Gotha-Altenburg (1745-1804) hired Baron Franz Xaver von Zach (1754-1832) as court astronomer in 1786. Immediatedly Zach started to make plans for instrumentation for a new observatory. But first they travelled with their instruments (a 2-foot Ramsden transit instrument, the Sisson quadrant, three Hadley sextants, two achromatic refractors and chronometers) to southern France. In Hyàres a tower of the wall around the town was converted into an observatory in 1787. For the building of the new observatory Zach had chosen a place outside of Gotha on the top of the Seeberg. The three main instruments were an 8-foot transit instrument made by Ramsden, a northern and southern mural quadrant made by Sisson and a zenith sector made by Cary, in addition an 8-foot circle made by Ramsden. By analysing the whole instrumentation of Gotha observatory, we can see a change around 1800 in the kind of instruments, from quadrants and sextants to the full circles and from the transit instrument to the meridian circle. The decline of the Gotha observatory started with the early death of the Duke in 1804 and the subsequent departure of Zach in 1806.

  15. Instrumentation issues in implementation science. (United States)

    Martinez, Ruben G; Lewis, Cara C; Weiner, Bryan J


    Like many new fields, implementation science has become vulnerable to instrumentation issues that potentially threaten the strength of the developing knowledge base. For instance, many implementation studies report findings based on instruments that do not have established psychometric properties. This article aims to review six pressing instrumentation issues, discuss the impact of these issues on the field, and provide practical recommendations. This debate centers on the impact of the following instrumentation issues: use of frameworks, theories, and models; role of psychometric properties; use of 'home-grown' and adapted instruments; choosing the most appropriate evaluation method and approach; practicality; and need for decision-making tools. Practical recommendations include: use of consensus definitions for key implementation constructs; reporting standards (e.g., regarding psychometrics, instrument adaptation); when to use multiple forms of observation and mixed methods; and accessing instrument repositories and decision aid tools. This debate provides an overview of six key instrumentation issues and offers several courses of action to limit the impact of these issues on the field. With careful attention to these issues, the field of implementation science can potentially move forward at the rapid pace that is respectfully demanded by community stakeholders.

  16. Developing a workplace resilience instrument. (United States)

    Mallak, Larry A; Yildiz, Mustafa


    Resilience benefits from the use of protective factors, as opposed to risk factors, which are associated with vulnerability. Considerable research and instrument development has been conducted in clinical settings for patients. The need existed for an instrument to be developed in a workplace setting to measure resilience of employees. This study developed and tested a resilience instrument for employees in the workplace. The research instrument was distributed to executives and nurses working in the United States in hospital settings. Five-hundred-forty completed and usable responses were obtained. The instrument contained an inventory of workplace resilience, a job stress questionnaire, and relevant demographics. The resilience items were written based on previous work by the lead author and inspired by Weick's [1] sense-making theory. A four-factor model yielded an instrument having psychometric properties showing good model fit. Twenty items were retained for the resulting Workplace Resilience Instrument (WRI). Parallel analysis was conducted with successive iterations of exploratory and confirmatory factor analyses. Respondents were classified based on their employment with either a rural or an urban hospital. Executives had significantly higher WRI scores than nurses, controlling for gender. WRI scores were positively and significantly correlated with years of experience and the Brief Job Stress Questionnaire. An instrument to measure individual resilience in the workplace (WRI) was developed. The WRI's four factors identify dimensions of workplace resilience for use in subsequent investigations: Active Problem-Solving, Team Efficacy, Confident Sense-Making, and Bricolage.

  17. A Database Management Assessment Instrument (United States)

    Landry, Jeffrey P.; Pardue, J. Harold; Daigle, Roy; Longenecker, Herbert E., Jr.


    This paper describes an instrument designed for assessing learning outcomes in data management. In addition to assessment of student learning and ABET outcomes, we have also found the instrument to be effective for determining database placement of incoming information systems (IS) graduate students. Each of these three uses is discussed in this…

  18. Cryogenic Caging for Science Instrumentation (United States)

    Penanen, Konstantin; Chui, Talso C.


    A method has been developed for caging science instrumentation to protect from pyro-shock and EDL (entry, descent, and landing) acceleration damage. Caging can be achieved by immersing the instrument (or its critical parts) in a liquid and solidifying the liquid by cooling. After the launch shock and/or after the payload has landed, the solid is heated up and evaporated.

  19. Motivation and Second Language Acquisition

    Directory of Open Access Journals (Sweden)

    Steve Buckledee


    Full Text Available A feature of Italian universities is the high student drop-out rate in nearly all degree courses. It is likely that among the causes of this phenomenon a significant factor is loss of motivation. This study represents the first stage of a longitudinal research project aimed at monitoring students’ motivation levels over a three-year period. At the beginning of the academic year 2008-2009 a questionnaire was administered to 150 newly enrolled students of English at the University of Cagliari in Italy. The closed-response items were designed to measure the respondents’ instrumental and intrinsic motivation. The responses were then considered in the light of the following variables: age, gender, level of competence in English and choice of degree course. The major finding was that a clear majority of respondents reported a considerably higher level of intrinsic than instrumental motivation, while the most significant variables were shown to be competence level and choice of degree.

  20. CLOUDCLOUD : general-purpose instrument monitoring and data managing software (United States)

    Dias, António; Amorim, António; Tomé, António


    An effective experiment is dependent on the ability to store and deliver data and information to all participant parties regardless of their degree of involvement in the specific parts that make the experiment a whole. Having fast, efficient and ubiquitous access to data will increase visibility and discussion, such that the outcome will have already been reviewed several times, strengthening the conclusions. The CLOUD project aims at providing users with a general purpose data acquisition, management and instrument monitoring platform that is fast, easy to use, lightweight and accessible to all participants of an experiment. This work is now implemented in the CLOUD experiment at CERN and will be fully integrated with the experiment as of 2016. Despite being used in an experiment of the scale of CLOUD, this software can also be used in any size of experiment or monitoring station, from single computers to large networks of computers to monitor any sort of instrument output without influencing the individual instrument's DAQ. Instrument data and meta data is stored and accessed via a specially designed database architecture and any type of instrument output is accepted using our continuously growing parsing application. Multiple databases can be used to separate different data taking periods or a single database can be used if for instance an experiment is continuous. A simple web-based application gives the user total control over the monitored instruments and their data, allowing data visualization and download, upload of processed data and the ability to edit existing instruments or add new instruments to the experiment. When in a network, new computers are immediately recognized and added to the system and are able to monitor instruments connected to them. Automatic computer integration is achieved by a locally running python-based parsing agent that communicates with a main server application guaranteeing that all instruments assigned to that computer are

  1. Data acquisition with direct memory access

    Directory of Open Access Journals (Sweden)

    Iu. Guzun


    Full Text Available This paper is concerned about using Direct Memory Access (DMA transfer for real-time data acquisitions from a plug-in data acquisition board Aquarius DSP-1. Since the conversion speed of the modern Analog to Digital Converters is increasevealy, the using of the interrupts for reading of the conversion results becomes impossible. For the data acquisition system, presented in this paper, this speed is up to 100 kS/s. This problem can be successfully solved using DMA technique. We subsequently describe the hardware of the data acquisition board, which has been used to acquire data. Next, have been presented the functions, in C programming language, for programming a data acquisition via DMA. Finally, we present some results obtained using this kind of data acquisitions, and some conclusions.

  2. The heliometric Astrolabe, a new instrument for solar diameter observations (United States)

    Andrei, A. H.; Reis Neto, E.; D'Ávila, V. A.; Penna, J. L.; Assafin, M.; Boscardin, S. C.; De Avila, K. N.


    The Observatorio Nacional takes part in the Reseau de Suivi au Sol du Rayon Solaire (the international solar diameter monitoring network) which co-participates in the PICARD micro satellite, to be launched in 2008 to study the Earth climate and Sun variability relationship. A new instrument, a heliometer, was devised in order to minimize the atmospheric turbulence and reach data accuracy compatible with PICARD's. The heliometer principle of double images will be added to the astrolabe metrological quality, and fully digitized acquisition. The objective is to obtain two simultaneous images from the Sun, with fixed angular separation of about 30', which variation will contain the signature of the diameter variation.

  3. Change Management in Mergers and Acquisitions


    Paul, Karnica


    More and more firms are looking at Mergers and Acquisitions as a relatively fast and efficient way to expand into new markets and incorporate new technologies. From a strategic point of view, Mergers and Acquisitions are thought to strengthen and sustain their position in the market place. Still this strategy’s success is by no means assured. On the contrary, a majority of these Mergers & Acquisitions fall short of their confirmed goals and objectives. Some failures can be explained by financ...

  4. Maximising Firm Value through Mergers and Acquisitions


    Lon, Wai See


    Mergers and acquisitions, literally, are centred on the objective to create economic value for firms and shareholders. Different mergers and acquisitions strategies would affect the extent of shareholder value. This study seeks to examine the value implications of mergers and acquisitions by studying shareholder value creation for a 60 Malaysian firms which have been actively involved in the cross-border and domestic diversifications during the period 1996 – 2004.Our focus in this study is to...

  5. Mergers and acquisitions : The road to success


    Hulthén, Andreas; Selguson, Kim


    Background: The most common reason to mergers and acquisitions is to generate synergies. Synergies emerge when two collaborating companies show a better result together than they would have done separately. Even though mergers and acquisitions have taken place since the beginning of the 17th century many of them still fail to succeed. There are many reasons why. Despite the fact that the reasons of failure have been known for a long time, new waves of mergers and acquisitions still appear. P...

  6. Instrumental variables and Mendelian randomization with invalid instruments (United States)

    Kang, Hyunseung

    Instrumental variables (IV) methods have been widely used to determine the causal effect of a treatment, exposure, policy, or an intervention on an outcome of interest. The IV method relies on having a valid instrument, a variable that is (A1) associated with the exposure, (A2) has no direct effect on the outcome, and (A3) is unrelated to the unmeasured confounders associated with the exposure and the outcome. However, in practice, finding a valid instrument, especially those that satisfy (A2) and (A3), can be challenging. For example, in Mendelian randomization studies where genetic markers are used as instruments, complete knowledge about instruments' validity is equivalent to complete knowledge about the involved genes' functions. The dissertation explores the theory, methods, and application of IV methods when invalid instruments are present. First, when we have multiple candidate instruments, we establish a theoretical bound whereby causal effects are only identified as long as less than 50% of instruments are invalid, without knowing which of the instruments are invalid. We also propose a fast penalized method, called sisVIVE, to estimate the causal effect. We find that sisVIVE outperforms traditional IV methods when invalid instruments are present both in simulation studies as well as in real data analysis. Second, we propose a robust confidence interval under the multiple invalid IV setting. This work is an extension of our work on sisVIVE. However, unlike sisVIVE which is robust to violations of (A2) and (A3), our confidence interval procedure provides honest coverage even if all three assumptions, (A1)-(A3), are violated. Third, we study the single IV setting where the one IV we have may actually be invalid. We propose a nonparametric IV estimation method based on full matching, a technique popular in causal inference for observational data, that leverages observed covariates to make the instrument more valid. We propose an estimator along with

  7. Acquired Inventors’ Productivity after Horizontal Acquisition

    DEFF Research Database (Denmark)

    Colombo, Massimo G.; Moreira, Solon; Rabbiosi, Larissa

    Effective integration of the R&D functions of the acquired and acquiring firms is essential for knowledge recombination after acquisition. However, prior research suggests that the post-acquisition integration process often damages the inventive labor force. We argue that an examination of the mu......Effective integration of the R&D functions of the acquired and acquiring firms is essential for knowledge recombination after acquisition. However, prior research suggests that the post-acquisition integration process often damages the inventive labor force. We argue that an examination...

  8. Consumption Skill Acquisition in Ski Schools

    DEFF Research Database (Denmark)

    Woermann, Niklas; Wieser, Verena


    Remedying the absence of a cultural theory of consumption skill acquisition, we use video data to explore how consumers learn in ski schools. We identify six modes of skill acquisition and theorize the interplay between the sensori-motor system, the conscious state of skillful coping, and the soc......Remedying the absence of a cultural theory of consumption skill acquisition, we use video data to explore how consumers learn in ski schools. We identify six modes of skill acquisition and theorize the interplay between the sensori-motor system, the conscious state of skillful coping...

  9. Acquisition in different and special subject areas

    CERN Document Server

    Katz, Linda S


    Learn how acquisitions librarians successfully serve specialized users! In this book, you'll find profiles, methods, and processes for acquisitions in specialized subject areas, such as local and regional poetry, oceanography, educational information in electronic formats, popular fiction, regional and ethnic materials, and more. Seasoned acquisitions librarians share their experiences in gathering the hard-to-find materials their libraries' highly specialized clients need to access. You'll also examine issues surrounding the acquisition of new reference tools that are vital in today's emergi

  10. Validating Acquisition IS Integration Readiness with Drills

    DEFF Research Database (Denmark)

    Wynne, Peter J.


    To companies, mergers and acquisitions are important strategic tools, yet they often fail to deliver their expected value. Studies have shown the integration of information systems is a significant roadblock to the realisation of acquisition benefits, and for an IT department to be ready......), to understand how an IT department can use them to validate their integration plans. The paper presents a case study of two drills used to validate an IT department’s readiness to carry out acquisition IS integration, and suggests seven acquisition IS integration drill characteristics others could utilise when...

  11. JIEDDO Experience Provides Rapid Acquisition Insights

    National Research Council Canada - National Science Library

    James P Craft


    .... JIDA's rapid acquisition capabilities were preserved by transitioning the expedient organization that received supplemental funding into the Defense Department's newest combat support agency (CSA...

  12. Seismic Endoscopy: Design of New Instruments (United States)

    Conil, F.; Nicollin, F.; Gibert, D.


    In order to perform 3D images around shallow-depth boreholes, in conditions in the field and within reasonable times of data acquisitions, several instrumental developments have been performed. The first development concerns the design of a directional probe working in the 20-100 kHz frequency range; the idea is to create a tool composed of multiple elementary piezoelectric entities able to cover the whole space to explore; made of special polyurethane rigid foam with excellent attenuation performances, the prototypes are covered by flexible polyurethane electric resin. By multiplying the number of elementary receptors around the vertical axes and piling up each elementary sensor, a complete design of multi-azimuth and multi-offset has been concepted. In addition to this, a test site has been built in order to obtain a controlled medium at typical scales of interest for seismic endoscopy and dedicated to experiment near the conditions in the field. Various reflectors are placed in well known positions and filled in an homogeneous cement medium; the whole edifice (2.2 m in diameter and 8 metres in depth) also contains 4 PVC tubes to simulate boreholes. The second part of this instrumental developments concern the synthesis of input signals; indeed, many modern devices used in ultrasonic experiment have non linear output response outside their nominal range: this is especially true in geophysical acoustical experiments when high acoustical power is necessary to insonify deep geological targets. Thanks to the high speed electronic and computerised devices now available, it is possible to plug in experimental set-ups into non linear inversions algorithms like simulated annealing. First experiments showed the robustness of the method in case of non linear analogic architecture. Large wavelet families have or example been constructed thanks to the method and multiscale Non Destructive Testing Method have been performed as an efficient method to detect and characterise

  13. Novel Aspects of the DESI Data Acquisition System (United States)

    Beaufore, Lucas; Honscheid, Klaus; Elliott, Ann; Dark Energy Spectroscopic Instrument Collaboration


    The Dark Energy Spectroscopic Instrument (DESI) will measure the effect of dark energy on the expansion of the universe. It will obtain optical spectra for tens of millions of galaxies and quasars, constructing a 3-dimensional map spanning the nearby universe to 10 billion light years. The survey will be conducted on the Mayall 4-meter telescope at Kitt Peak National Observatory starting in 2018. In order to achieve these scientific goals the DESI collaboration is building a high throughput spectrograph capable of observing thousands of spectra simultaneously. In this presentation we discuss the DESI instrument control and data acquisition system that is currently being developed to operate the 5,000 fiber positioners in the focal plane, the 10 spectrographs each with three CDD cameras and every other aspect of the instrument. Special emphasis will be given to novel aspects of the design including the use of inexpensive Linux-based microcontrollers such as the Raspberry PI to control a number of DESI hardware components.

  14. Acquisition of Ice-Tethered Profilers with Velocity (ITP-V) Instruments for Future Arctic Studies (United States)


    San Diego, CA, IEEE Xplore . Toole, J. M., R. A. Krishfield, M.-L. Timmennans, and A. Proshutinsky, 2011: The Ice-Tethered Profiler: Argo ofthe Arctic, Oceanogr., 24, 126-135. 4 ...observations from Ice-Tethered Profilers, MTS/ IEEE Oceans’ 2015, Washington DC, 1-10. Krishfield, R., J. Toole, A. Proshutinsky, and M.-L. Timmennans, 2008

  15. Electric vehicle data acquisition system

    DEFF Research Database (Denmark)

    Svendsen, Mathias; Winther-Jensen, Mads; Pedersen, Anders Bro


    A data acquisition system for electric vehicles is presented. The system connects to the On-board Diagnostic port of newer vehicles, and utilizes the in-vehicle sensor network, as well as auxiliary sensors, to gather data. Data is transmitted continuously to a central database for academic...... and industrial applications, e.g. research in electric vehicle driving patterns, vehicle substitutability analysis and fleet management. The platform is based on a embedded computer running Linux, and features a high level of modularity and flexibility. The system operates independently of the make of the car......, by using the On-board Diagnostic port to identify car model and adapt its software accordingly. By utilizing on-board Global Navigation Satellite System, General Packet Radio Service, accelerometer, gyroscope and magnetometer, the system not only provides valuable data for research in the field of electric...

  16. Language acquisition is language change. (United States)

    Crain, Stephen; Goro, Takuya; Thornton, Rosalind


    According to the theory of Universal Grammar, the primary linguistic data guides children through an innately specified space of hypotheses. On this view, similarities between child-English and adult-German are as unsurprising as similarities between cousins who have never met. By contrast, experience-based approaches to language acquisition contend that child language matches the input, with nonadult forms being simply less articulated versions of the forms produced by adults. This paper reports several studies that provide support for the theory of Universal grammar, and resist explanation on experience-based accounts. Two studies investigate English-speaking children's productions, and a third examines the interpretation of sentences by Japanese speaking children. When considered against the input children are exposed to, the findings of these and other studies are consistent with the continuity hypothesis, which supposes that child language can differ from the language spoken by adults only in ways that adult languages can differ from each other.

  17. Fluorometric field instrument for continuous measurement of atmospheric hydrogen sulfide. (United States)

    Toda, K; Dasgupta, P K; Li, J; Tarver, G A; Zarus, G M


    A sensitive (limit of detection approximately detector. Acquisition and interpretation of signal and all flow control are carried out via a mininotebook personal computer (PC) using custom software written in HP-VEE. The instrument provides for self-calibration and zero functions using an on-board permeation tube enclosed in a thermostated block, at any preprogrammed desired interval. During sampling, the computed H2S concentration is stored every 2 min. The complete system, including the PC, is operated in the field by a 12-V marine battery. The system was field tested near oil field operations in West Texas and showed good correlations with a concurrently operated lead acetate tape-based commercial sampler, with a response speed and time resolution much better than that of the latter instrument.

  18. 75 FR 53169 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-45; Small Entity Compliance Guide (United States)


    ... precedes this document. These documents are also available via the Internet at Acquisition Regulation; Federal Acquisition Circular 2005-45; Small Entity Compliance Guide AGENCIES...

  19. 76 FR 39231 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-53; Introduction (United States)


    ... Acquisition Regulation; Federal Acquisition Circular 2005-53; Introduction AGENCIES: Department of Defense (Do...), published in the Federal Register at 74 FR 51225 on October 6, 2009, entitled ``Federal Leadership on...

  20. Transitional Governance in External Technology Trajectories : Connecting Pre-acquisition collaboration to post-acquisition integration

    NARCIS (Netherlands)

    Faems, D.L.M.


    Collaboration and acquisition have traditionally been observed as two alternative strategies to get access to external technologies. However, real option scholars have recently argued that firms can also engage in transitional technology sourcing trajectories where collaboration and acquisition are

  1. 77 FR 19975 - VA Acquisition Regulation: Simplified Acquisition Procedures for Health-Care Resources (Section... (United States)


    ... Service (003A2A), Office of Acquisition, Logistics and Construction, Department of Veterans Affairs, 810... concept in acquisitions that all offerors are treated fairly. Consideration may be given to updating the...

  2. Instrumentation Automation for Concrete Structures; Report 1: Instrumentation Automation Techniques (United States)


    REPORT REMR-r::S-5 INSTRUMENl h 1 !0!\\’ /I’J\\UTOMA-r!n FUK CONCRETE STRUCTURES 1 ~eport 1 INSTRUMENTATION AUTOMATION TECHf\\liQUES by ,John Lindsey...measurements of structural behavior ano environmental conditions at large concrete structures , along with the suggested methods to replace or retrofit...8217.!.’RODUCTION 1. This report is the first of ~ series of three reports entitled, "Instrumentation l:iutomation for Concrete Structures ", and issued by

  3. Instrumental variable estimation with heteroskedasticity and many instruments


    Hausman, Jerry; Newey, Whitney; Chao, John; Swanson, Norman


    It is common practice in econometrics to correct for heteroskedasticity.This paper corrects instrumental variables estimators with many instruments for heteroskedasticity.We give heteroskedasticity robust versions of the limited information maximum likelihood (LIML) and Fuller (1977, FULL) estimators; as well as heteroskedasticity consistent standard errors thereof. The estimators are based on removing the own observation terms in the numerator of the LIML variance ratio. We derive asymptotic...

  4. The wide field imager instrument for Athena (United States)

    Meidinger, Norbert; Eder, Josef; Eraerds, Tanja; Nandra, Kirpal; Pietschner, Daniel; Plattner, Markus; Rau, Arne; Strecker, Rafael


    The WFI (Wide Field Imager) instrument is planned to be one of two complementary focal plane cameras on ESA's next X-ray observatory Athena. It combines unprecedented survey power through its large field of view of 40 amin x 40 amin together with excellent count rate capability (>= 1 Crab). The energy resolution of the silicon sensor is state-of-the-art in the energy band of interest from 0.2 keV to 15 keV, e.g. the full width at half maximum of a line at 7 keV will be MOSFET integrated onto a fully depleted 450 μm thick silicon bulk. Two detectors are planned for the WFI instrument: A large-area detector comprising four sensors with a total of 1024 x 1024 pixels and a fast detector optimized for high count rate observations. This high count rate capable detector permits for bright point sources with an intensity of 1 Crab a throughput of more than 80% and a pile-up of less than 1%. The fast readout of the DEPFET pixel matrices is facilitated by an ASIC development, called VERITAS-2. Together with the Switcher-A, a control ASIC that allows for operation of the DEPFET in rolling shutter mode, these elements form the key components of the WFI detectors. The detectors are surrounded by a graded-Z shield, which has in particular the purpose to avoid fluorescence lines that would contribute to the instrument background. Together with ultra-thin coating of the sensor and particle identification by the detector itself, the particle induced background shall be minimized in order to achieve the scientific requirement of a total instrumental background value smaller than 5 x 10-3 cts/cm2/s/keV. Each detector has its dedicated detector electronics (DE) for supply and data acquisition. Due to the high frame rate in combination with the large pixel array, signal correction and event filtering have to be done on-board and in real-time as the raw data rate would by far exceed the feasible telemetry rate. The data streams are merged and compressed in the Instrument Control and

  5. The JCMT future instrumentation project (United States)

    Dempsey, Jessica T.; Ho, Paul T. P.; Walther, Craig; Friberg, Per; Bintley, Dan; Chen, Ming-Tang


    Under the new operational purview of the East Asian Observatory, the JCMT continues to produce premier wide-field submillimetre science. Now the Observatory looks to embark on an ambitious series of instrumentation upgrades and opportunities to keep the telescope at the bleeding edge of its performance capabilities, whilst harnessing the collaborative expertise of the participating EAO regions and its JCMT partners. New heterodyne instruments include a new receiver at 230 GHz, a super array (90 pixels) at 345 GHz and the upgrade possibilities for the continuum camera SCUBA-2. In addition, the opportunities for PI and visiting instruments, including TimePilot and Gismo-2 will be described.

  6. 75 FR 14067 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-40; Small Entity Compliance Guide (United States)


    ... the Internet at . FOR FURTHER INFORMATION CONTACT: The analyst whose name... Acquisition Regulation; Federal Acquisition Circular 2005-40; Small Entity Compliance Guide AGENCIES... Federal Acquisition Regulation (FAR). Interested parties may obtain further information regarding this...

  7. 75 FR 39420 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-44; Small Entity Compliance Guide (United States)


    ... the Internet at . FOR FURTHER INFORMATION CONTACT: The analyst whose name... Acquisition Regulation; Federal Acquisition Circular 2005-44; Small Entity Compliance Guide AGENCY: Department... Federal Acquisition Regulation (FAR). Interested parties may obtain further information regarding this...

  8. 75 FR 19179 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-41; Small Entity Compliance Guide (United States)


    ... Acquisition Regulation; Federal Acquisition Circular 2005-41; Small Entity Compliance Guide AGENCIES... the summary of the rule appearing in Federal Acquisition Circular (FAC) 2005-41 which amends the... construction projects where the total cost to the Government is $25 million or more in order to promote economy...

  9. How different are monolingual and bilingual acquisition? How different are monolingual and bilingual acquisition?

    Directory of Open Access Journals (Sweden)

    Annick De Houwer


    Full Text Available This paper compares monolingual acquisition to the acquisition of two languages from infancy. Basis for the comparison is the acquisition literature. Specifically for bilingual acquisition, the paper relies on findings from studies on young bilingual children who together are acquiring 13 languages in 14 different combinations. The data available to date strongly suggest that in essence, bilingual and monolingual children go through the primary language development process in fundamentally similar ways. There are also striking similarities between bilingual and monolingual children for one particular language-in-acquisition. The acquisition process, then, appears to be very robust, and quite immune to the fact whether a child is growing up with two languages or just one. This paper compares monolingual acquisition to the acquisition of two languages from infancy. Basis for the comparison is the acquisition literature. Specifically for bilingual acquisition, the paper relies on findings from studies on young bilingual children who together are acquiring 13 languages in 14 different combinations. The data available to date strongly suggest that in essence, bilingual and monolingual children go through the primary language development process in fundamentally similar ways. There are also striking similarities between bilingual and monolingual children for one particular language-in-acquisition. The acquisition process, then, appears to be very robust, and quite immune to the fact whether a child is growing up with two languages or just one.

  10. 76 FR 30362 - Federal Acquisition Regulation; Submission for OMB Review; Acquisition of Helium (United States)


    ...; Submission for OMB Review; Acquisition of Helium AGENCY: Department of Defense (DOD), General Services... approved information collection requirement concerning acquisition of helium. Public comments are... Collection 9000- 0113, Acquisition of Helium, by any of the following methods: : http://www...

  11. Enseignement des langues et theories d'acquisition Sprachunterricht unde Spracherwerbstheorien. (Language Teaching and Acquisition Theories). (United States)

    Schwarz, Alexander, Ed.


    This collection of articles on language teaching and language acquisition theories includes: "Enseignement des langues et theories de l'acquisition. Introduction au colloque" ("Language Teaching and Theories of Acquisition. Introduction to the Colloquium") (Rene Richterich); "Apprendre une langue dans l'interaction verbale" ("Language Learning in…

  12. Secondary particle acquisition system for the CERN beam wire scanners upgrade

    CERN Document Server

    Sirvent, J L; Emery, J; Diéguez, A


    The increasing requirements of CERN experiments make essential the upgrade of beam instrumentation in general, and high accuracy beam profile monitors in particular. The CERN Beam Instrumentation Group has been working during the last years on the Wire Scanners upgrade. These systems cross a thin wire through a circulating beam, the resulting secondary particles produced from beam/wire interaction are detected to reconstruct the beam profile. For the new secondary shower acquisition system, it is necessary to perform very low noise measurements with high dynamic range coverage. The aim is to design a system without tuneable parameters and compatible for any beam wire scanner location at the CERN complex. Polycrystalline chemical vapour deposition diamond detectors (pCVD) are proposed as new detectors for this application because of their radiation hardness, fast response and linearity over a high dynamic range. For the detector readout, the acquisition electronics must be designed to exploit the detector capa...

  13. DA+ data acquisition and analysis software at the Swiss Light Source macromolecular crystallography beamlines. (United States)

    Wojdyla, Justyna Aleksandra; Kaminski, Jakub W; Panepucci, Ezequiel; Ebner, Simon; Wang, Xiaoqiang; Gabadinho, Jose; Wang, Meitian


    Data acquisition software is an essential component of modern macromolecular crystallography (MX) beamlines, enabling efficient use of beam time at synchrotron facilities. Developed at the Paul Scherrer Institute, the DA+ data acquisition software is implemented at all three Swiss Light Source (SLS) MX beamlines. DA+ consists of distributed services and components written in Python and Java, which communicate via messaging and streaming technologies. The major components of DA+ are the user interface, acquisition engine, online processing and database. Immediate data quality feedback is achieved with distributed automatic data analysis routines. The software architecture enables exploration of the full potential of the latest instrumentation at the SLS MX beamlines, such as the SmarGon goniometer and the EIGER X 16M detector, and development of new data collection methods.

  14. German norms for semantic typicality, age of acquisition, and concept familiarity. (United States)

    Schröder, Astrid; Gemballa, Teresa; Ruppin, Steffie; Wartenburger, Isabell


    The present study introduces the first substantial German database with norms for semantic typicality, age of acquisition, and concept familiarity for 824 exemplars of 11 semantic categories, including four natural (ANIMALS, BIRDS, FRUITS,: and VEGETABLES: ) and five man-made (CLOTHING, FURNITURE, VEHICLES, TOOLS: , and MUSICAL INSTRUMENTS: ) categories, as well as PROFESSIONS: and SPORTS: . Each category exemplar in the database was collected empirically in an exemplar generation study. For each category exemplar, norms for semantic typicality, estimated age of acquisition, and concept familiarity were gathered in three different rating studies. Reliability data and additional analyses on effects of semantic category and intercorrelations between age of acquisition, semantic typicality, concept familiarity, word length, and word frequency are provided. Overall, the data show high inter- and intrastudy reliabilities, providing a new resource tool for designing experiments with German word materials. The full database is available in the supplementary material of this file and also at .

  15. Technical Training seminar: Texas Instruments

    CERN Multimedia


    Monday 6 November TECHNICAL TRAINING SEMINAR 14:00 to 17:30 - Training Centre Auditorium (bldg. 593) Texas Instruments Technical Seminar Michael Scholtholt, Field Application Engineer / TEXAS INSTRUMENTS (US, D, CH) POWER - A short approach to Texas Instruments power products Voltage mode vs. current mode control Differentiating DC/DC converters by analyzing control and compensation schemes: line / load regulation, transient response, BOM, board space, ease-of-use Introduction to the SWIFT software FPGA + CPLD power solutions WIRELESS / CHIPCON Decision criteria when choosing a RF platform Introduction to Texas Instruments wireless products: standardized platforms proprietary platforms ( 2.4 GHz / sub 1 GHz) development tools Antenna design: example for 2.4 GHz questions, discussion Industrial partners: Robert Medioni, François Caloz / Spoerle Electronic, CH-1440 Montagny (VD), Switzerland Phone: +41 24 447 0137, email:, Language: English. Free s...

  16. Intelligent instrumentation principles and applications

    CERN Document Server

    Bhuyan, Manabendra


    With the advent of microprocessors and digital-processing technologies as catalyst, classical sensors capable of simple signal conditioning operations have evolved rapidly to take on higher and more specialized functions including validation, compensation, and classification. This new category of sensor expands the scope of incorporating intelligence into instrumentation systems, yet with such rapid changes, there has developed no universal standard for design, definition, or requirement with which to unify intelligent instrumentation. Explaining the underlying design methodologies of intelligent instrumentation, Intelligent Instrumentation: Principles and Applications provides a comprehensive and authoritative resource on the scientific foundations from which to coordinate and advance the field. Employing a textbook-like language, this book translates methodologies to more than 80 numerical examples, and provides applications in 14 case studies for a complete and working understanding of the material. Beginn...

  17. Compact Formaldehyde Fluorescence Instrument Element (United States)

    National Aeronautics and Space Administration — The successful completion of this IRAD will deliver a fully functional instrument at TRL 6.  The key characteristics that we will demonstrate are simplicity,...

  18. Virtual Sensor Test Instrumentation Project (United States)

    National Aeronautics and Space Administration — Mobitrum has started the development of virtual sensor test instrumentation in Phase I for characterization and measurement of ground testing of propulsion systems....

  19. Avanços em psicofarmacologia - mecanismos de ação de psicofármacos hoje Advances in psychopharmacology: mechanism of action of psychoactive drugs today

    Directory of Open Access Journals (Sweden)

    Clarice Gorenstein


    Full Text Available Desde o início da história da psicofarmacologia moderna, na década de 40, vários avanços foram obtidos na elucidação do mecanismo de ação dos compostos psicoativos. O artigo aborda tais avanços enfocando as principais técnicas utilizadas, desde o desenvolvimento das técnicas de mensuração de aminas por emissão de fluorescência e da técnica de ligação fármaco-receptor, até a incorporação de técnicas sofisticadas, tais como as moleculares, para o estudo das alterações pós-receptor, o uso de marcadores genéticos e técnicas de imagem (PET, SPECT. Espera-se que tais progressos levem à elucidação dos mecanismos de ação dos psicofármacos, permitindo o desenvolvimento de novas moléculas terapêuticas específicas para regular as alterações subjacentes aos transtornos psiquiátricos.Since the beginning of the history of modern psychopharmacology on the 40's, many advances were obtained on the understanding of the mechanism of action of psychotropic drugs. This article gives an overview of such advances, since the introduction of the early techniques, such as the measurement of amines by fluorescence and the receptor-binding studies up to the incorporation of sophisticated techniques such as the molecular, to study the post-receptor alterations, the genetic and the neuroimage techniques. These kind of studies might help to better understand the mechanisms of action of psychotropics, allowing the development of new therapeutic substances to regulate the alterations which underlie the psychiatric disorders.

  20. [25 Years After Re-Unification of Germany: An Overview on Eastern German Psychiatry. Part 1: Post-War Era, Pavlovization, Psychopharmacological Era and Social Psychiatric Reform Movement]. (United States)

    Steinberg, H


    This is the first of a 2-part study on the history of psychiatry in Eastern Germany, i. e. the Soviet Occupied Zone and later German Democratic Republic. It mainly covers the years post World War II up until the beginning of the 1970s. The first post-war years were determined by the new power holders' attempts to overcome National Socialist (Nazi) heritage and to re-organize mental health and care in general. The doctrine of a strict denazifization in East Germany must, however, be regarded as a myth. Promoted by centralized organization, there was an increase in communist party-ideological influence and harassment as well as aligning scientific views and research with Soviet paradigms (Pavlovization) during the 1950s and early 1960s. This, however, led to an enormous rise in exodus of skilled labor to West Germany, which in turn further increased the notorious lack of staff. After the erection of the inner-German wall, this problem was mitigated, yet never fully solved over the 40 years of the existence of the GDR. Despite adverse conditions, East German psychiatrists made major original contributions to the development of psychiatry in general, at least up until the 1960s. Academic psychiatry was mainly based on biological concepts that were further promoted by new somatic and psychopharmacological therapeutic options. In the 1960s, social psychiatric reformist forces emerged, primarily in the large psychiatric hospitals. The improvements achieved by these forces, however, were not implemented on a nation-wide scale, but mainly restricted to one particular or several institutions. © Georg Thieme Verlag KG Stuttgart · New York.