Social dimensions of science-humanitarian collaboration: lessons from Padang, Sumatra, Indonesia.

Science.gov (United States)

Shannon, Rachel; Hope, Max; McCloskey, John; Crowley, Dominic; Crichton, Peter

2014-07-01

This paper contains a critical exploration of the social dimensions of the science-humanitarian relationship. Drawing on literature on the social role of science and on the social dimensions of humanitarian practice, it analyses a science-humanitarian partnership for disaster risk reduction (DRR) in Padang, Sumatra, Indonesia, an area threatened by tsunamigenic earthquakes. The paper draws on findings from case study research that was conducted between 2010 and 2011. The case study illustrates the social processes that enabled and hindered collaboration between the two spheres, including the informal partnership of local people and scientists that led to the co-production of earthquake and tsunami DRR and limited organisational capacity and support in relation to knowledge exchange. The paper reflects on the implications of these findings for science-humanitarian partnering in general, and it assesses the value of using a social dimensions approach to understand scientific and humanitarian dialogue. © 2014 The Author(s). Disasters © Overseas Development Institute, 2014.

Dangers, delights, and destiny on the sea: fishers along the East coast of north sumatra, indonesia.

Science.gov (United States)

Markkanen, Pia

2005-01-01

This article describes a collaborative project between the International Labour Organization's International Programme on the Elimination of Child Labour (IPEC) and the Lowell Center for Sustainable Production, in identifying work hazards of fishers along the east coast of North Sumatra, Indonesia, in July 2004. The study employed qualitative investigation techniques: participant observations at fishing villages and harbors; and interviews with local fishers and skippers. Fishers work long hours in life-threatening conditions, often with low pay. It would be synergistic to incorporate fishing safety and health policies and advocacy efforts into reconstruction undertakings of fisheries devastated by the 2004 tsunami.

3D Agro-ecological Land Use Planning Using Surfer Tool for Sustainable Land Management in Sumani Watershed, West Sumatra Indonesia

OpenAIRE

Aflizar; Alarima Cornelius Idowu; Roni Afrizal; Jamaluddin; Husnain; Tsugiyuki Masunaga; Edi Syafri; Muzakir

2013-01-01

Estimation of soil erosion 3D (E3D) provides basic information that can help manage agricultural areas sustainably, which has not been sufficiently conducted in Indonesia. Sumani watershed is main rice production area in West Sumatra which has experienced environmental problem such as soil erosion and production problem in recent years. 3D Agro-ecological land use planning based on soil erosion 3D hazard and economic feasibility analyses consist of production cost and prize data for each crop...

Developing community-based mangrove management through eco-tourism in North Sumatra, Indonesia

Science.gov (United States)

Basyuni, M.; Bimantara, Y.; Siagian, M.; Wati, R.; Slamet, B.; Sulistiyono, N.; Nuryawan, A.; Leidonad, R.

2018-03-01

Mangrove forests in North Sumatera, Indonesia existed in the east coast of Sumatera Island and commonly thrived in Langkat, Deli Serdang, Batubara, Tanjung Balai, Asahan, Labuhanbatu until Serdang Bedagai. The present study describes the developing community-based mangrove management (CBMM) through eco-tourism in two locations, Lubuk Kertang (LK) of Langkat and Sei Nagalawan (SN) of Serdang Bedagai, North Sumatra, Indonesia. Mangrove ecosystem, coastal villagers and visitors, and related stakeholder were analyzed to present the potential of mangrove ecosystem, the ecological suitability, and the carrying capacity then continued with SWOT (Strengths, Weaknesses, Opportunities, and Threats) analysis. Results showed that mangrove diversity in LK consist of fifteen species which Rhizophora apiculata and Avicennia lanata dominated the area, where mangroves in SN found seven species dominated by R. apiculata and A. officinalis. Based on the suitability level of mangrove ecosystem for ecotourism development, LK and SN were categorized as suitable and conditionally suitable, respectively. The carrying capacity of mangrove ecotourism for LK and SN were 36 and 36 people/day respectively. SWOT analysis revealed that both locations of eco-tourism have a potential eco-tourism attraction, high mangrove biodiversity, possible human resources, and real people’s perception on the importance of mangrove conservation, and relatively easy access. The study present suggested that mangrove ecotourism is a sustainable form of land use, to contributing the environmental protection and providing socio-economic benefits to the local people through indirect values of the natural resources.

Two new spiders from Sumatra (Araneae, Telemidae and Ochyroceratidae)

NARCIS (Netherlands)

Brignoli, P.M.

1977-01-01

Apneumonella jacobsoni n. sp. is described (♀, ♂ unknown; typ. loc.: Fort de Kock, Sumatra, Indonesia); this species, which can be distinguished from all other known Telemids by general morphology, genitalia, chelicerae, etc., is provisionally included in Apneumonella; the differential characters

Impact of The N - S Fracture Zone Along The Indo-Australia Plate Analyzed from Local Seismic Data In The Western Offshore of Sumatra, Indonesia

Science.gov (United States)

Haridhi, H. A.; Klingelhoefer, F.; Huang, B. S.; Lee, C. S.

2015-12-01

Large subduction earthquake have repeatedly occurred along the Sumatra and Andaman subduction zones where the Indo-Australia plate is subducting beneath the Eurasian plate. We have analyzed earthquake data from local seismic network along the Sumatra region that provided by the Meteorology Climatology Geophysical Agencies of Indonesia (MCGAI), giving a reliable P-wave velocity model by using joint inversion of picked P-wave travel time using VELEST and a re-scanned single channel seismic reflection of Sumatra cruise I and II. As much as 1,503 events are being analyzed, that is from two years and three months of data recording (2009/04 - 2011/07). The VELEST and DD technique are used to relocate all events by forcing the obtained velocity model. It is found that the surface deformation and earthquake cluster are strongly influenced by the impact of an N - S subparalel fracture zone along the Indo-Australia plate. This also explains the seismic gaps along the Sumatra and Andaman subduction zones. So far, the intriguing seismogenic behaviour and forearc structure are not well explained by the existing models. Therefore, the planned IODP Expedition 362 is trying to ground truth the scientific questions. The aftershock earthquake data are huge, but they will provide a gateway to help the understanding of this shallow megathrust slip and reduce its devastated harzards.

Space Radar Image of Central Sumatra, Indonesia

Science.gov (United States)

1994-01-01

This is a radar image of the central part of the island of Sumatra in Indonesia that shows how the tropical rainforest typical of this country is being impacted by human activity. Native forest appears in green in this image, while prominent pink areas represent places where the native forest has been cleared. The large rectangular areas have been cleared for palm oil plantations. The bright pink zones are areas that have been cleared since 1989, while the dark pink zones are areas that were cleared before 1989. These radar data were processed as part of an effort to assist oil and gas companies working in the area to assess the environmental impact of both their drilling operations and the activities of the local population. Radar images are useful in these areas because heavy cloud cover and the persistent smoke and haze associated with deforestation have prevented usable visible-light imagery from being acquired since 1989. The dark shapes in the upper right (northeast) corner of the image are a chain of lakes in flat coastal marshes. This image was acquired in October 1994 by the Spaceborne Imaging Radar C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) onboard the space shuttle Endeavour. Environmental changes can be easily documented by comparing this image with visible-light data that were acquired in previous years by the Landsat satellite. The image is centered at 0.9 degrees north latitude and 101.3 degrees east longitude. The area shown is 50 kilometers by 100 kilometers (31 miles by 62 miles). The colors in the image are assigned to different frequencies and polarizations of the radar as follows: red is L-band horizontally transmitted, horizontally received; green is L-band horizontally transmitted, vertically received; blue is L-band vertically transmitted, vertically received. SIR-C/X-SAR, a joint mission of the German, Italian and United States space agencies, is part of NASA's Mission to Planet Earth program.

Habitat characteristic of macrozoobenthos in Naborsahan River of Toba Lake, North Sumatra, Indonesia

Science.gov (United States)

Basyuni, M.; Lubis, M. S.; Suryanti, A.

2018-02-01

This research described the relative abundance, dominance index, and index of macrozoobenthos equitability in Naborsahan River of Toba Lake, North Sumatra, Indonesia. The purposive random sampling at three stations was used to characterize the biological, chemical, and physical parameters of macrozoobenthos. The highest relative abundance of macrozoobenthos found at station 2 (99.96%). By contrast, the highest dominance index was at station 3 (0.31), and the maximum equitability index found at station 1 (0.94). The present results showed diversity parameters among the stations. A principal component analysis (PCA) was used to determine the habitat characteristics of macrozoobenthos. PCA analysis depicted that six parameters studied, brightness, turbidity, depth, temperature, dissolved oxygen (DO) and biochemical oxygen demand (BOD5) play a significant role on the relative abundance, dominance index, and equitability index. PCA analysis suggested that station 3 was suitable habitat characteristic for the life of macro-zoobenthos indicating of the negative axis. The present study demonstrated the six parameters should be conserved to support the survival of macrozoobenthos.

AGRICULTURE PHENOMENA AND PERSPECTIVES OF LEBAK SWAMP IN JAKABARING SOUTH SUMATRA, INDONESIA

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Elisa Wildayana

2017-11-01

Full Text Available The research aimed to analyze agriculture phenomena and perspectives of lebak swamp in Jakabaring South Sumatra Indonesia. The research used mix methods of quantitative and qualitative approaches. The description of the research area was assisted with interpretation of Landsat images in 1987 and 2015. The research resulted that farmer’s groups living in Jakabaring are divided into four group, namely indigenous people (people of Ogan, Komering, Musi, Enim, and Palembang, new comers (Javanese, spontaneous migration (Buginese, Banjarnese, Bataknese and outside spontaneous migration (Chinese, Arabic. The total area of Jakabaring is approximately 5,525 ha, around 2,700 ha (48.87 % was already landfilled by the Government in 1990, while the remaining 2,825 ha (51.13 % is still not reclaimed. The landfill materials were directly sucked from mud, sand, silt and stones of the Musi River. Each lebak swamp typology shows specific soil characters, but after landfills all soils became homogenous because of uniform materials of landfills. Patterns of land degradation after landfills are classified into three groups, namely making layers of water impermeability, changing vegetation types of land cover, and decreasing type and density of vegetation.

Carbon dioxide emissions from forestry and peat land using land-use/land-cover changes in North Sumatra, Indonesia

Science.gov (United States)

Basyuni, M.; Sulistyono, N.; Slamet, B.; Wati, R.

2018-03-01

Forestry and peat land including land-based is one of the critical sectors in the inventory of CO2 emissions and mitigation efforts of climate change. The present study analyzed the land-use and land-cover changes between 2006 and 2012 in North Sumatra, Indonesia with emphasis to CO2 emissions. The land-use/land-cover consists of twenty-one classes. Redd Abacus software version 1.1.7 was used to measure carbon emission source as well as the predicted 2carbon dioxide emissions from 2006-2024. Results showed that historical emission (2006-2012) in this province, significant increases in the intensive land use namely dry land agriculture (109.65%), paddy field (16.23%) and estate plantation (15.11%). On the other hand, land-cover for forest decreased significantly: secondary dry land forest (7.60%), secondary mangrove forest (9.03%), secondary swamp forest (33.98%), and the largest one in the mixed dry land agriculture (79.96%). The results indicated that North Sumatra province is still a CO2 emitter, and the most important driver of emissions mostly derived from agricultural lands that contributed 2carbon dioxide emissions by 48.8%, changing from forest areas into degraded lands (classified as barren land and shrub) shared 30.6% and estate plantation of 22.4%. Mitigation actions to reduce carbon emissions was proposed such as strengthening the forest land, rehabilitation of degraded area, development and plantation forest, forest protection and forest fire control, and reforestation and conservation activity. These mitigation actions have been simulated to reduce 15% for forestry and 18% for peat land, respectively. This data is likely to contribute to the low emission development in North Sumatra.

Detailed seismotectonic analysis of Sumatra subduction zone revealed by high precision earthquake location

Science.gov (United States)

Sagala, Ricardo Alfencius; Harjadi, P. J. Prih; Heryandoko, Nova; Sianipar, Dimas

2017-07-01

Sumatra was one of the most high seismicity regions in Indonesia. The subduction of Indo-Australian plate beneath Eurasian plate in western Sumatra contributes for many significant earthquakes that occur in this area. These earthquake events can be used to analyze the seismotectonic of Sumatra subduction zone and its system. In this study we use teleseismic double-difference method to obtain more high precision earthquake distribution in Sumatra subduction zone. We use a 3D nested regional-global velocity model. We use a combination of data from both of ISC (International Seismological Center) and BMKG (Agency for Meteorology Climatology and Geophysics, Indonesia). We successfully relocate about 6886 earthquakes that occur on period of 1981-2015. We consider that this new location is more precise than the regular bulletin. The relocation results show greatly reduced of RMS residual of travel time. Using this data, we can construct a new seismotectonic map of Sumatra. A well-built geometry of subduction slab, faults and volcano arc can be obtained from the new bulletin. It is also showed that at a depth of 140-170 km, there is many events occur as moderate-to-deep earthquakes, and we consider about the relation of the slab's events with volcanic arc and inland fault system. A reliable slab model is also built from regression equation using new relocated data. We also analyze the spatial-temporal of seismotectonic using b-value mapping that inspected in detail horizontally and vertically cross-section.

Fossilization History of Fossil Resin from Jambi Province (Sumatra, Indonesia Based on Physico-Chemical Studies

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Beata Naglik

2018-03-01

Full Text Available A unique specimen of fossil resin originating from the Dipterocarpaceae tree family found in Miocene brown coal deposits in Jambi Province (Sumatra, Indonesia was investigated via microscopic observations, microhardness testing and infrared and Raman spectroscopic methods. Its form is rare in nature, being an aggregate of three varieties of resin differing in colour, transparency and internal structure. This suggests the formation of the resins at different stages. Further alteration processes, including fossilization and maturation of the resin in a swamp environment resulted in stepwise aromatization of the cyclohexane ring in steroids and cross-linking through formation of ester bonds as well as carbon–carbon bonds between steroid molecules. The various environmental and geological conditions affecting the formation processes of the resins were recorded in their physico-chemical properties. Additionally, heating conditions accelerated by volcanism were proposed as a factor determining the maturation grade of the resin.

Changing of Sumatra backswamp peat properties by seawater and zeolite application

Science.gov (United States)

Sarifuddin; Nasution, Z.; Rauf, A.; Mulyanto, B.

2018-02-01

This research attempts to improve the properties of backswamp peatsoil originated from Asahan District, North Sumatra Indonesia by adding sea water and zeolite using factorial randomized block design with volume of sea water as first factor, consisting of without seawater, 500 ml, 1000 ml and 1500 ml and second factor are dosages of zeolite consisting of without zeolite, 100 g, 200 g each 10 kgs of wet peat soil. at green house in faculty of agriculture University of Sumatra Utara (USU) Medan, Indonesia. The result showed that the application of seawater decreased pH, C/N and Cation Exchange Capacity and increased of base saturation of peat soil. Adding of zeolite minerals can buffered the increasing of acidity and Electric Conductivity caused by sea water application. Interaction seawater + zeolite decreased of C/N and increased of percent of base saturation.

Soil Nitrogen-Cycling Responses to Conversion of Lowland Forests to Oil Palm and Rubber Plantations in Sumatra, Indonesia.

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Kara Allen

Full Text Available Rapid deforestation in Sumatra, Indonesia is presently occurring due to the expansion of palm oil and rubber production, fueled by an increasing global demand. Our study aimed to assess changes in soil-N cycling rates with conversion of forest to oil palm (Elaeis guineensis and rubber (Hevea brasiliensis plantations. In Jambi Province, Sumatra, Indonesia, we selected two soil landscapes - loam and clay Acrisol soils - each with four land-use types: lowland forest and forest with regenerating rubber (hereafter, "jungle rubber" as reference land uses, and rubber and oil palm as converted land uses. Gross soil-N cycling rates were measured using the 15N pool dilution technique with in-situ incubation of soil cores. In the loam Acrisol soil, where fertility was low, microbial biomass, gross N mineralization and NH4+ immobilization were also low and no significant changes were detected with land-use conversion. The clay Acrisol soil which had higher initial fertility based on the reference land uses (i.e. higher pH, organic C, total N, effective cation exchange capacity (ECEC and base saturation (P≤0.05-0.09 had larger microbial biomass and NH4+ transformation rates (P≤0.05 compared to the loam Acrisol soil. Conversion of forest and jungle rubber to rubber and oil palm in the clay Acrisol soil decreased soil fertility which, in turn, reduced microbial biomass and consequently decreased NH4+ transformation rates (P≤0.05-0.09. This was further attested by the correlation of gross N mineralization and microbial biomass N with ECEC, organic C, total N (R=0.51-0. 76; P≤0.05 and C:N ratio (R=-0.71 - -0.75, P≤0.05. Our findings suggest that the larger the initial soil fertility and N availability, the larger the reductions upon land-use conversion. Because soil N availability was dependent on microbial biomass, management practices in converted oil palm and rubber plantations should focus on enriching microbial biomass.

Soil Nitrogen-Cycling Responses to Conversion of Lowland Forests to Oil Palm and Rubber Plantations in Sumatra, Indonesia

Science.gov (United States)

Tjoa, Aiyen; Veldkamp, Edzo

2015-01-01

Rapid deforestation in Sumatra, Indonesia is presently occurring due to the expansion of palm oil and rubber production, fueled by an increasing global demand. Our study aimed to assess changes in soil-N cycling rates with conversion of forest to oil palm (Elaeis guineensis) and rubber (Hevea brasiliensis) plantations. In Jambi Province, Sumatra, Indonesia, we selected two soil landscapes – loam and clay Acrisol soils – each with four land-use types: lowland forest and forest with regenerating rubber (hereafter, “jungle rubber”) as reference land uses, and rubber and oil palm as converted land uses. Gross soil-N cycling rates were measured using the 15N pool dilution technique with in-situ incubation of soil cores. In the loam Acrisol soil, where fertility was low, microbial biomass, gross N mineralization and NH4 + immobilization were also low and no significant changes were detected with land-use conversion. The clay Acrisol soil which had higher initial fertility based on the reference land uses (i.e. higher pH, organic C, total N, effective cation exchange capacity (ECEC) and base saturation) (P≤0.05–0.09) had larger microbial biomass and NH4 + transformation rates (P≤0.05) compared to the loam Acrisol soil. Conversion of forest and jungle rubber to rubber and oil palm in the clay Acrisol soil decreased soil fertility which, in turn, reduced microbial biomass and consequently decreased NH4 + transformation rates (P≤0.05–0.09). This was further attested by the correlation of gross N mineralization and microbial biomass N with ECEC, organic C, total N (R=0.51–0. 76; P≤0.05) and C:N ratio (R=-0.71 – -0.75, P≤0.05). Our findings suggest that the larger the initial soil fertility and N availability, the larger the reductions upon land-use conversion. Because soil N availability was dependent on microbial biomass, management practices in converted oil palm and rubber plantations should focus on enriching microbial biomass. PMID:26222690

Mapping the outdoor gamma dose rate in Indonesia

International Nuclear Information System (INIS)

Iskandar, Dadong; Syarbaini, Sutarman; Bunawas, Kusdiana

2008-01-01

Full text: Indonesia is the largest archipelago in the world, comprising five main islands - Java, Sumatra, Sulawesi, Kalimantan and Papua - as well as 30 archipelagoes totaling 17,508 islands with about 6000 of those inhabited. Mapping the outdoor gamma dose rate in Indonesia is a research project conducted by National Nuclear Energy Agency since 2005 aiming to produce a baseline data map as an overview for planning purposes. In these three years 4 main islands has been measured. The grid system has been used in the research. In Sumatra Island the grid is 50 x 50 km 2 , while in Java 40 x 40 km 2 , in Kalimantan 60 x 60 km 2 , and in Sulawesi 40 x 40 km 2 . The gamma dose rates have been measured by Mini Gamma Ray Spectrometer Model GR-130 made by Exploranium-Canada. Figure 1 shows the map of outdoor gamma dose rate in Indonesia. Range of dose rate are in Sumatra from 22,96 ± 0,46 n Sv/h to 186,08 ± 3,72 n Sv/h, in Java 11,32 ± 0,72 n Sv/h to 127,54 ± 6,14 n Sv/h, in Kalimantan 10.72 ± 8.32 n Sv/h to 349,48 ± 57,21 n Sv/h, and in Sulawesi 17.7 ± 11,5 n Sv/h to 467 ± 102 n Sv/h. The arithmetic and geometric mean of dose rate in Indonesia are 68 n Sv/h and 53 n Sv/h, respectively. In general, outdoor gamma dose rate in Indonesia is in a normal range. There are some regions have anomaly of gamma dose rate, for examples at North Sumatra 186.08 ± 3,72 n Sv/h (N 2.12727, E 99.80909), at West Kalimantan 349,48 ± 57,21 n Sv/h (S 1.39507, E 110.57584), at West Sulawesi 487 ± 103 n Sv/h (S 2.95781, E 118.86995), etc. These data is very useful as a radiation baseline in Indonesia. (author)

Analyses of surface motions caused by the magnitude 9.0 2004 Sumatra earthquake

DEFF Research Database (Denmark)

Khan, Shfaqat Abbas; Gudmundsson, Ó.

The Sumatra, Indonesia, earthquake on December 26th was one of the most devastating earthquakes in history. With a magnitude of Mw = 9.0 it is the forth largest earthquake recorded since 1900. It occurred about one hundred kilometers off the west coast of northern Sumatra, where the relatively thin...... of years. The result was a devastating tsunami hitting coastlines across the Indian Ocean killing more than 225,000 people in Sri Lanka, India, Indonesia, Thailand and Malaysia. An earthquake of this magnitude is expected to involve a displacement on the fault on the order of 10 meters. But, what...... was the actual amplitude of the surface motions that triggered the tsunami? This can be constrained using the amplitudes of elastic waves radiated from the earthquake, or by direct measurements of deformation. Here we present estimates of the deformation based on continuous Global Positioning System (GPS...

Knowledge transfer to builders in post-disaster housing reconstruction in West-Sumatra of Indonesia

Science.gov (United States)

Hidayat, Benny; Afif, Zal

2017-11-01

Housing is the most affected sector by disasters as can be observed after the 2009 earthquake in West Sumatra province in Indonesia. As in Indonesian construction industry, the housing post-disaster reconstruction is influenced by knowledge and skills of builders or laborers, or locally known as `tukang'. After the earthquake there were trainings to transfer knowledge about earthquake-safe house structure for the builders in the post-disaster reconstruction. This study examined the effectiveness of the training in term of understanding of the builders and application of the new knowledge. Ten semi-structured interviews with the builders were conducted in this study. The results indicate that the builders with prior housing construction experience can absorb and understand the new knowledge about earthquake-safe house structure. Combination of lecturing and practice sessions also help the builders to understand the knowledge. However, findings of this research also suggest there is a problem in implementation of the new knowledge. Utilization of earthquake-safe house structure may leads to a rise in house cost. As a result, some house owners prefer to save money than to adopt the new knowledge.

Recent developments in forestry and land use in Indonesia

NARCIS (Netherlands)

Meijer, W.

1974-01-01

Dr. W. Meijer, who is Dutch-born, worked in Indonesia from 1951 to 1958, first at Bogor, then at Pajakumbuh, Sumatra, and was Forest Botanist in Sabah for several years, revisited Indonesia with a National Science Foundation travel grant under an NSF-AID (Agency for International Development)

FDI in Tourism Sector and Economic Growth in Sumatra Utara

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Parhimpunan Simatupang

2014-09-01

Full Text Available Globalization and neo liberal policies such as liberalization and privatization have generated a significant growth for FDI and considered an important source for capital and foreign currency, capable of spurring economic growth in developing countries. One sector that received particular attention, due to its significant contributions towards economic development, especially in Indonesia, is tourism. Tourism investments in Indonesia are mainly focused on the development of fully-integrated resort sites that help boost the construction of tourist facilities such as hotels and the development of the surrounding environment through social and cultural aspects. The total contribution of travel and tourism to GDP was IDR736.3 billion or 8.9% of GDP in 2012. Foreign direct tourism investments grew by 210% between 2011 and 2012, or at an annual compound average growth rate of 38% between 2006 and 2012. While the implications are at national level, not much could be gathered on the local perspectives. This paper intends to explore the implication of FDI in tourism sector towards economic growth in one of tourism attraction provinces in Indonesia—Sumatra Utara. Specifically, which economic factors contributed towards FDI inflows and their impacts on economic growth in Sumatra Utara.

Paleoenvironmental conditions in the late Paleogene, Sumatra, Indonesia

Science.gov (United States)

O'shea, Natalie; Arthur Bettis, E.; Zaim, Yahdi; Rizal, Yan; Aswan, Aswan; Gunnell, Gregg F.; Zonneveld, John-Paul; Ciochon, Russell L.

2015-11-01

A stratified paleosol sequence exposed in an open pit mine in central Sumatra provides a record of the paleoenvironmental conditions in the lower reaches of a large river system in the late Paleogene (latest Eocene or Oligocene). Morphological, geochemical, and stable isotope data suggest that the sequence represents a mosaic of local environmental conditions changing from estuarine to riverine up section. Weakly expressed soils formed on low-lying estuary surfaces, while more well expressed soils formed on higher, better drained surfaces. Peatlands (coal) with clayey subsoils were along the estuary margins. Well-expressed soils with evidence of clay translocation and chemical weathering become more common higher in the section where alluvial deposits associated with a meandering river are dominant. Stable carbon isotope ratios support a paleolandscape dominated by C3 plants with input by C4 vegetation limited to a few intervals. Finally, whole-rock geochemistry suggests moderate chemical weathering consistent with a tropical locality. This multi-proxy paleoenvironmental reconstruction suggests a highly productive lowland forest environment at this locality in the late Paleogene and provides the first direct examination of the terrestrial environment in Sumatra at this time. The limited fossil record in Island Southeast Asia during this time period is likely a result of poor bone and shell preservation in tropical forest environments combined with a general lack of systematic prospecting. However, our continuing work in this area has produced a relatively diverse assemblage of fossil vertebrates, now including fishes, amphibians, turtles, crocodiles, and mammals, as well as a growing diversity of fossil plants.

Environmental dynamics and carbon accumulation rate of a tropical peatland in Central Sumatra, Indonesia

Science.gov (United States)

Hapsari, Kartika Anggi; Biagioni, Siria; Jennerjahn, Tim C.; Reimer, Peter Meyer; Saad, Asmadi; Achnopha, Yudhi; Sabiham, Supiandi; Behling, Hermann

2017-08-01

Tropical peatlands are important for the global carbon cycle as they store 18% of the total global peat carbon. As they are vulnerable to changes in temperature and precipitation, a rapidly changing environment endangers peatlands and their carbon storage potential. Understanding the mechanisms of peatland carbon accumulation from studying past developments may, therefore, help to assess the future role of tropical peatlands. Using a multi-proxy palaeoecological approach, a peat core taken from the Sungai Buluh peatland in Central Sumatra has been analyzed for its pollen and spore, macro charcoal and biogeochemical composition. The result suggests that peat and C accumulation rates were driven mainly by sea level change, river water level, climatic variability and anthropogenic activities. It is also suggested that peat C accumulation in Sungai Buluh is correlated to the abundance of Freycinetia, Myrtaceae, Calophyllum, Stemonuraceae, Ficus and Euphorbiaceae. Sungai Buluh has reasonable potential for being a future global tropical peat C sinks. However, considering the impact of rapid global climate change in addition to land-use change following rapid economic growth in Indonesia, such potential may be lost. Taking advantage of available palaeoecological records and advances made in Quaternary studies, some considerations for management practice such as identification of priority taxa and conservation sites are suggested.

NILAI FILOSOFIS BUDAYA MATRILINEAL DI MINANGKABAU (RELEVANSINYA BAGI PENGEMBANGAN HAK-HAK PEREMPUAN DI INDONESIA

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Iva Ariani

2016-08-01

Full Text Available This research is a qualitative research to find an essence of matrilineal culture in Minangkabau tradition from the philosophical perspective of Feminism. Method of data collection is dividing research areas in West Sumatra into two big groups that are Minang Pesisir and Minang Bukit. Then, collecting data through direct interview and observation to get data about matrilineal system in West Sumatra. Data which has collected then be analyzed using interpretation and hermeneutics method and described as a concept to develop the rights of enforcer process of woman in Indonesia. This research is to develop the woman movements and law concerning femininity in Indonesia that is more suitable with the personality and cultural of Indonesia because it lifted from local and cultural wisdom in Indonesia. The expectation is that it will be able to more suitable to the agenda of offering values of feminist appropriate for public of Indonesia.

Indonesia palm oil production without deforestation and peat conversion by 2050.

Science.gov (United States)

Afriyanti, Dian; Kroeze, Carolien; Saad, Asmadi

2016-07-01

Palm oil is a promising source of cooking oil and biodiesel. The demand for palm oil has been increasing worldwide. However, concerns exist surrounding the environmental and socio-economic sustainability of palm oil production. Indonesia is a major palm oil producing country. We explored scenarios for palm oil production in Indonesia until 2050, focusing on Sumatra, Kalimantan and Papua. Our scenarios describe possible trends in crude palm oil production in Indonesia, while considering the demand for cooking oil and biodiesel, the available land for plantations, production capacity (for crude palm oil and fresh fruit bunches) and environmentally restricting conditions. We first assessed past developments in palm oil production. Next, we analysed scenarios for the future. In the past 20years, 95% of the Indonesian oil palm production area was in Sumatra and Kalimantan and was increasingly cultivated in peatlands. Our scenarios for the future indicate that Indonesia can meet a considerable part of the global and Asian demand for palm oil, while avoiding further cultivation of peatlands and forest. By 2050, 264-447Mt crude palm oil may be needed for cooking oil and biodiesel worldwide. In Indonesia, the area that is potentially suitable for oil palm is 17 to 26Mha with a potential production rate of 27-38t fresh fruit bunches/ha, yielding 130-176Mt crude palm oil. Thus Indonesia can meet 39-60% of the international demand. In our scenarios this would be produced in Sumatra (21-26%), Kalimantan (12-16%), and Papua (2%). The potential areas include the current oil palm plantation in mineral lands, but exclude the current oil palm plantations in peatlands. Copyright © 2016 Elsevier B.V. All rights reserved.

Permian to recent volcanism in northern sumatra, indonesia: a preliminary study of its distribution, chemistry, and peculiarities

Science.gov (United States)

Rock, N. M. S.; Syah, H. H.; Davis, A. E.; Hutchison, D.; Styles, M. T.; Lena, Rahayu

1982-06-01

Sumatra has been a ‘volcanic arc’, above an NE-dipping subduction zone, since at least the Late Permian. The principal volcanic episodes in Sumatra N of the Equator have been in the Late Permian, Late Mesozoic, Palaeogene, Miocene and Quaternary. Late Permian volcanic rocks, of limited extent, are altered porphyritic basic lavas interstratified with limestones and phyllites. Late Mesozoic volcanic rocks, widely distributed along and W of the major transcurrent. Sumatra Fault System (SFS), which axially bisects Sumatra, include ophiolite-related spilites, andesites and basalts. Possible Palaeogene volcanic rocks include an altered basalt pile with associated dyke-swarm in the extreme NW, intruded by an Early Miocene (19 my) dioritic stock; and variable pyroxene rich basic lavas and agglomerates ranging from alkali basaltic to absarokitic in the extreme SW. Miocene volcanic rocks, widely distributed (especially W of the SFS), and cropping out extensively along the W coast, include calc-alkaline to high-K calc-alkaline basalts, andesites and dacites. Quaternary volcanoes (3 active, 14 dormant or extinct) are irregularly distributed both along and across the arc; thus they lie fore-arc of the SFS near the Equator but well back-arc farther north. The largest concentration of centres, around Lake Toba, includes the >2000 km3 Pleistocene rhyolitic Toba Tuffs. Quaternary volcanics are mainly calc-alkaline andesites, dacites and rhyolites with few basalts; they seem less variable, but on the whole more acid, than the Tertiary. The Quaternary volcanism is anomalous in relation to both southern Sumatra and adjacent Java/Bali: in southern Sumatra, volcanoes are regularly spaced along and successively less active away from the SFS, but neither rule holds in northern Sumatra. Depths to the subduction zone below major calc-alkaline volcanoes in Java/Bali are 160-210 km, but little over 100 km in northern Sumatra, which also lacks the regular K2O-depth correlations seen in

International Uranium Resources Evaluation Project (IUREP) national favourability studies: Indonesia

International Nuclear Information System (INIS)

1977-10-01

Indonesia is a country of south east Asia comprising a large island group extending east-west for over 3000 miles. The geology of Indonesia is fairly well known but is extremely complicated. Successive mountain movements took place around an ancient crustal area. The oldest, of Permian-Triassic age formed northeast Sumatra, northern Java and western Kalimantan. This was followed by the Sumatra orogenesis and finally in Cretaceous and Tertiary times the southern half of Java and the islands as far as New Guinea were formed. Geological studies tend to indicate that the most favourable uranium areas are likely to be in West Sumatra and West Kalimantan. Exploration by the Directorate of Survey and Geology of the National Atomic Energy Agency has been carried out on a small scale since 1961. Exploration concession have been granted to French, German and Japanese organisations. No uranium reserve or resource figures have ever been stated but small occurrences and radioactive anomalies have been found in West and South Sumatra, West and Central Kalimantan and in West Irian. Although the geology of some areas appears to be favourable, little success has attended exploration efforts to date and thus the Speculative Potential is noted as between 1,000 and 10,000 tonnes uranium. (author)

A tree species inventory in a one-hectare plot at the Batang Gadis National Park, North Sumatra, Indonesia

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Kuswata Kartawinata

2003-12-01

Full Text Available KARTAWINATA, KUSWATA; SAMSOEDIN, ISMAYADI; HERIYANTO, M. AND AFRIASTINI, J. J. 2004. A tree species inventory in a one-hectare plot at the Batang Gadis National Park, North Sumatra, Indonesia. Reinwardtia 12 (2: 145 – 157. The results of the inventory of trees with DBH ≥ 10 cm shows that 184 species in 41 families, represented by 583 individuals with the total basal areas of 40.56 m² occurred in the one-hectare plot sampled. Together with the saplings and shrubs the number of species was 240 belonging to 47 families. The forest is richer in tree species than other lowland forests in North Sumatra, but poorer than those in Borneo and the Malay Peninsula. Dipterocarps constituted 18.42 % of total species with basal area of 18.99 m² or 46.82 % of the total basal area in the plot. The most prominent species was Shorea gibbosa. Hopea nigra, reported to be rare in Bangka and Belitung, occurred here as one of the ten leading species. The species-area curve shows that a considerable number of additional species was encountered more or less steadily up to one hectare and there was no indication of levelling off. A simulated profile diagram shows the forest may be stratified into five layers: (1 emergent layer, (2 upper canopy, (3 middle canopy, (4 lower canopy and (5 ground canopy. Dipterocarps were leading species in the emergent layer, upper canopy and middle canopy. Only 82 species were regenerating as represented by their presence in the sapling stage ranging from 5 to 50 plants/hectare. Macaranga lowii King ex Hook. f. dominated the section which seemed to be previously occupied by gaps.

Contemporary Minangkabau food culture in West Sumatra, Indonesia.

Science.gov (United States)

Lipoeto, N I; Mmedsci; Agus, Z; Oenzil, F; Masrul, M; Wattanapenpaiboon, N

2001-01-01

Diet has a strong relationship with food culture and changes in it are likely to be involved in the pathogenesis of newly emergent degenerative diseases. To obtain in-depth opinions about the food culture of Minangkabau people, focus group discussions were conducted in a Minangkabau region, represented by four villages in West Sumatra, Indonesia, from January to March 1999. The members of the discussion groups were principally women aged from 35 to 82 years old. Minangkabau culture is matriarchal and matrilineal which accounts for female gender dominants in the discussions. Rice, fish, coconut and chilli are the basic ingredients of the Minangkabau meals. Meat, especially beef and chicken, is mainly prepared for special occasions; pork is not halal and therefore not eaten by Muslim Minangkabau people; and for reasons of taste preference and availability, lamb, goat and wild game are rarely eaten. However, rendang, a popular meat dish, has been identified as one of the Minangkabau food culture characteristic dishes. Vegetables are consumed daily. Fruit is mainly seasonal, although certain kinds of fruit, such as banana, papaya and citrus, can be found all year around. Coconut has an important role in Minangkabau food culture and is the main source of dietary fat. While almost all food items consumed by the Minangkabau can be cooked with coconut milk, fried food with coconut oil is considered to be a daily basic food. Desiccated coconut is also used as a food ingredient on about a weekly basis and in snack foods almost every day. Although there have been no changes in food preparation and there is a slight difference in taste preference between the young and the old generations, there has been a dramatic shift in food preferences, which is reflected in the changing percentage of energy consumed over the past 15 years. The traditional combination of rice, fish and coconut in Minangkabau culture goes back hundreds of years, long before the emergence of the degenerative

Indonesia lays out a power privatisation agenda

Energy Technology Data Exchange (ETDEWEB)

1991-07-15

Indonesia is preparing to embark on a major power sector privatisation programme in order to stimulate the installation of new electricity capacity, which at present stands at little more than 9,000 MW. This figure, however, represents a 100% increase in capacity in the last five years, up from 4,600 MW in 1984-85. Much of the new capacity is coal-based and the state utility, PLN, new operates 1,730 MW of coal-fired capacity. Backed by East Kalimantan and Sumatran coal deposits, Indonesia plans to further increase domestic coal use for electric power generation over the next 10 years. The PLN will add three 600MW units at Suralaya, four 400MW units at Paiton in East Java, two 65MW mine-mouth units at Bukit Asam, Sumatra and two 65MW mine-mouth units at Ombilin, Sumatra. Private generators will be given the opportunity to participate in coal-based electricity supply under build-own-operate schemes through the installation of four 600 MW units at Paiston, five 600 MW units at Tanjing Jati, Central Java, two 600 MW units in west Java, two 65 MW units at Taraham, Sumatra and four 45 MW units at Banjarmasin, Kalimantan. A substantial amount of private capacity is in fact already under development, particularly in Sumatra and Batam island. Some private companies have identified projects that will be required to supply power to industrial estates; some projects may consist of several units totalling 1,000 MW or more at a single site.

Mental Health in Sumatra After the Tsunami

Science.gov (United States)

Frankenberg, Elizabeth; Friedman, Jed; Gillespie, Thomas; Ingwersen, Nicholas; Pynoos, Robert; Rifai, Iip Umar; Sikoki, Bondan; Steinberg, Alan; Sumantri, Cecep; Suriastini, Wayan; Thomas, Duncan

2008-01-01

Objectives. We assessed the levels and correlates of posttraumatic stress reactivity (PTSR) of more than 20000 adult tsunami survivors by analyzing survey data from coastal Aceh and North Sumatra, Indonesia. Methods. A population-representative sample of individuals interviewed before the tsunami was traced in 2005 to 2006. We constructed 2 scales measuring PTSR by using 7 symptom items from the Post Traumatic Stress Disorder (PTSD) Checklist–Civilian Version. One scale measured PTSR at the time of interview, and the other measured PTSR at the point of maximum intensity since the disaster. Results. PTSR scores were highest for respondents from heavily damaged areas. In all areas, scores declined over time. Gender and age were significant predictors of PTSR; markers of socioeconomic status before the tsunami were not. Exposure to traumatic events, loss of kin, and property damage were significantly associated with higher PTSR scores. Conclusions. The tsunami produced posttraumatic stress reactions across a wide region of Aceh and North Sumatra. Public health will be enhanced by the provision of counseling services that reach not only people directly affected by the tsunami but also those living beyond the area of immediate impact. PMID:18633091

Medicinal plants used in the treatment of diabetes in karo ethnic, north sumatra, indonesia

Science.gov (United States)

Raja Nasution, Barita; Alief Aththorick, T.; Rahayu, Suci

2018-03-01

Medicinal plants derived from traditional medicines have played an important role in managing a variety of healthcare and diseases in Karo ethnic in North Sumatra, Indonesia. The study aimed to document the ethnobotanical information on medicinal plants used by traditional healers of Karo ethnic in the treatment of diabetes and to assess the crude extract of phytochemical constituents qualitatively from medicinal plant organ. The study was conducted on two Karo sub-ethnic living at the highland (Karo Gugung) in Karo Regency and the lowland (Karo Jahe) in Langkat Regency with the length of the study was eight months of observation. The survey was conducted using open-ended interviews among four traditional healers those who were selected by snowball sampling method; quantitative analysis of ethnobotanical data was performed by calculating the familiarity index (Fi). Fresh plant samples which were used for phytochemical analysis were collected using participatory method. The results showed that 15 plants were used to treat diabetes by Karo traditional healers. The plants are Blumea balsamifera, Nypa fruticans, Bischofia javanica, Eleutherine americana, Allium cepa, A. sativum, Eugenia polyantha, Piper betle, P. nigrum, Citrus aurantiifolia, Boesenbergia pandurata, Curcuma longa, Kaempferia galanga, Zingiber montanum, and Z. officinale. Familiarity index (Fi) value of each plant was 25 which explained that each of medicinal plant was used by only one traditional healer. The phytochemical screening showed that the crude plant extracts contained phenolic, terpenoid, steroid, and saponin.

Spatial Mapping for Managing Oxidized Pyrite (FeS2 in South Sumatra Wetlands, Indonesia

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M. Edi Armanto

2016-02-01

Full Text Available The research aimed to analyze spatial mapping for managing oxidized pyrite (FeS2 in South Sumatra wetlands, Indonesia. The field observations are done by exploring several transect on land units. The field description refers to Soil Survey Staff (2014. Water and soil samples were taken from selected key areas for laboratory analysis. The vegetation data was collected by making sample plots (squares method placed on each vegetation type with plot sizes depending on the vegetation type, namely 10 x 10 m for secondary forests and 5 x 5 m for shrubs and grass. The observations of surface water level were done during the river receding with units of m above sea level (m asl. The research results showed that pyrite formation is largely determined by the availability of natural vegetation as Sulfur (S donors, climate and uncontrolled water balance and supporting fauna such as crabs and mud shrimp.  Climate and water balance as well as supporting faunas is the main supporting factors to accelerate the process of pyrite formation. Oxidized pyrite serves to increase soil acidity, becomes toxic to fish ponds and arable soils, plant growth and disturbing the water and soil nutrient balances. Oxidized pyrite is predominantly accelerated by the dynamics of river water and disturbed natural vegetation by human activities.  The pyrite oxidation management approach is divided into three main components of technologies, namely water management, land management and commodity management.

Toerbeurtrijstbouw : individuele en collectieve rechten in de landbouw van Kerinci in Sumatra, Indonesië

NARCIS (Netherlands)

Ven, van de J.W.

2006-01-01

In Kerinci, on theislandofSumatrainIndonesia, different categories of collective property co-exist with different types of individual

Connecting the fragmented habitat of endangered mammals in the landscape of Riau–Jambi–Sumatera Barat (RIMBA, central Sumatra, Indonesia (connecting the fragmented habitat due to road development

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Barano Siswa Sulistyawan

2017-01-01

Full Text Available The trend of wildlife habitat fragmentation worldwide continues as a result of anthropogenic activities on development of a linear infrastructure and land use changes, which is often implemented as part of spatial planning policies. In this paper we expand upon an existing approach to design wildlife corridors through habitat quality assessment. We used models of Habitat Quality of Integrated Valuation of Ecosystem Services and Trade-offs (InVEST and Corridor Design tools. The habitat quality model of InVEST provides a rapid approach to assess status and change of biodiversity, and can contribute to enhanced corridor design of fragmented wildlife habitat. We conducted an assessment of habitat quality of the RIMBA corridor landscape, which is part of Riau, Jambi and West Sumatra provinces of central Sumatra Island. The result of the habitat quality model was used as the main input to evaluate habitat connectivity and assess the target segment of roads that cross the modelled corridor. We found 20 wildland blocks, the total area of the corridor modelled including wildland blocks was calculated as about 0.77 million hectares. We have obtained accurate quantitative measurement of the length of roads crossing the corridor, with a total of 417.78 km (artery 10.31 km; collector 19.52 km; and local 1987.9 km roads. This method can be replicated as an approach in valuing the quality of habitat as part of the implementation of the presidential decree of Sumatra Island Spatial Planning. This may also be applied to the spatial planning of other major islands in Indonesia and elsewhere.

Status of peatland degradation and development in Sumatra and Kalimantan.

Science.gov (United States)

Miettinen, Jukka; Liew, Soo Chin

2010-01-01

Peatlands cover around 13 Mha in Sumatra and Kalimantan, Indonesia. Human activities have rapidly increased in the peatland ecosystems during the last two decades, invariably degrading them and making them vulnerable to fires. This causes high carbon emissions that contribute to global climate change. For this article, we used 94 high resolution (10-20 m) satellite images to map the status of peatland degradation and development in Sumatra and Kalimantan using visual image interpretation. The results reveal that less than 4% of the peatland areas remain covered by pristine peatswamp forests (PSFs), while 37% are covered by PSFs with varying degree of degradation. Furthermore, over 20% is considered to be unmanaged degraded landscape, occupied by ferns, shrubs and secondary growth. This alarming extent of degradation makes peatlands vulnerable to accelerated peat decomposition and catastrophic fire episodes that will have global consequences. With on-going degradation and development the existence of the entire tropical peatland ecosystem in this region is in great danger.

Fire intensity and phosphorus availability in Sumatra

International Nuclear Information System (INIS)

Ketterings, Q.M.; Bigham, J.M.; Noordwijk, M. van

1999-01-01

Fire is still widely used as a tool for land clearing in Indonesia. The environmental problems caused by these became an international issue in the fall of 1997 when smoke originating from land clearing activities in Sumatra and West Kalimantan blanketed not only large parts of Indonesia but also the neighboring countries of Malaysia, Singapore, Brunei, the Philippines and Thailand. Alternatives must be found. For alternatives to slash-and-burn to be acceptable, they should address both the problems and the benefits of burning as a land clearing method for small rubber and oil palm farmers. A social/economic/agronomic survey conducted in Sepunggur, Jambi Province, Sumatra, indicated that burning: 1) was the cheapest and easiest way to create space to plant and walk in the field; 2) added free fertilizer in the form of ash; 3) improved soil structure allowing faster establishment of seedlings; 4) reduced weed/tree competition; and 5) reduced problems with pest/diseases. Farmers also indicated that harveys delays and yield reductions would lead to an increase in poverty, mainly due to a loss in ash (fertilizer) addition if fire was no longer used. Slash-sell wood-and-burn is a alternative that has the advantage of maintaining at least part of the benefits of burning while reducing air pollution. The sale of wood (if permitted) could supply the farmer with an extra source of income. Before this alternative can be promoted, it should be known what a reduction in fuel load and fire intensity will mean for soil fertility and plant growth and thus for the economic situation of farmers that depend on it. Two questions need to be answered: 1) how is fir intensity related to nutrient availability; and 2) how important are short-term fertilizer (ash) additions versus longer lasting, heat induced changes in soil mineralogical properties? Refs. 11 (author)

Deforestation trend in North Sumatra over 1990-2015

Science.gov (United States)

Basyuni, M.; Sulistiyono, N.; Wati, R.; Hayati, R.

2018-02-01

Deforestation and forest degradation have been previously reported to contributing greenhouse gas emission, the primary driver of global warming. The present paper studies deforestation and reforestation trend in North Sumatra, Indonesia using land-use/land-cover change from 1990-2015. The land-use consists of three classes derived from forest land (primary and secondary dry land forest, primary and secondary swamp forest, primary and secondary mangrove forest). Non-Forest (shrub, oil palm plantation, forest plantation, settlement, barren land, swamp shrub, dry land farming, mixed dry land farming, paddy field, aquaculture, airport, transmigration, and mining), and water body (water and swamp). Results showed that from 33 regencies/city in North Sumatra, among them, 25 districts deforested, which was the highest deforestation rate in Labuhanbatu and South Labuhanbatu (2,238.08 and 1,652.55 ha/year, respectively), only one area reforested, and seven districts showed no deforestation or reforestation. During 25 years observed, the forest has been deforested 22.92%, while nonforest has been increased 11.33% of land-use. The significant increasing loss of North Sumatran forest implies conservation efforts and developing sustainable forest management.

2004 Sumatra Tsunami

Directory of Open Access Journals (Sweden)

Vongvisessomjai, S.

2005-09-01

Full Text Available A catastrophic tsunami on December 26, 2004 caused devastation in the coastal region of six southern provinces of Thailand on the Andaman Sea coast. This paper summaries the characteristics of tsunami with the aim of informing and warning the public and reducing future casualties and damage.The first part is a review of the records of past catastrophic tsunamis, namely those in Chile in 1960, Alaska in 1964, and Flores, Java, Indonesia, in 1992, and the lessons drawn from these tsunamis. An analysis and the impact of the 2004 Sumatra tsunami is then presented and remedial measures recommended.Results of this study are as follows:Firstly, the 2004 Sumatra tsunami ranked fourth in terms of earthquake magnitude (9.0 M after those in 1960 in Chile (9.5 M, 1899 in Alaska (9.2 M and 1964 in Alaska (9.1 M and ranked first in terms of damage and casualties. It was most destructive when breaking in shallow water nearshore.Secondly, the best alleviation measures are 1 to set up a reliable system for providing warning at the time of an earthquake in order to save lives and reduce damage and 2 to establish a hazard map and implement land-use zoning in the devastated areas, according to the following principles:- Large hotels located at an elevation of not less than 10 m above mean sea level (MSL- Medium hotels located at an elevation of not less than 6 m above MSL- Small hotel located at elevation below 6 m MSL, but with the first floor elevated on poles to allow passage of a tsunami wave- Set-back distances from shoreline established for various developments- Provision of shelters and evacuation directionsFinally, public education is an essential part of preparedness.

A probabilistic tsunami hazard assessment for Indonesia

Science.gov (United States)

Horspool, N.; Pranantyo, I.; Griffin, J.; Latief, H.; Natawidjaja, D. H.; Kongko, W.; Cipta, A.; Bustaman, B.; Anugrah, S. D.; Thio, H. K.

2014-11-01

Probabilistic hazard assessments are a fundamental tool for assessing the threats posed by hazards to communities and are important for underpinning evidence-based decision-making regarding risk mitigation activities. Indonesia has been the focus of intense tsunami risk mitigation efforts following the 2004 Indian Ocean tsunami, but this has been largely concentrated on the Sunda Arc with little attention to other tsunami prone areas of the country such as eastern Indonesia. We present the first nationally consistent probabilistic tsunami hazard assessment (PTHA) for Indonesia. This assessment produces time-independent forecasts of tsunami hazards at the coast using data from tsunami generated by local, regional and distant earthquake sources. The methodology is based on the established monte carlo approach to probabilistic seismic hazard assessment (PSHA) and has been adapted to tsunami. We account for sources of epistemic and aleatory uncertainty in the analysis through the use of logic trees and sampling probability density functions. For short return periods (100 years) the highest tsunami hazard is the west coast of Sumatra, south coast of Java and the north coast of Papua. For longer return periods (500-2500 years), the tsunami hazard is highest along the Sunda Arc, reflecting the larger maximum magnitudes. The annual probability of experiencing a tsunami with a height of > 0.5 m at the coast is greater than 10% for Sumatra, Java, the Sunda islands (Bali, Lombok, Flores, Sumba) and north Papua. The annual probability of experiencing a tsunami with a height of > 3.0 m, which would cause significant inundation and fatalities, is 1-10% in Sumatra, Java, Bali, Lombok and north Papua, and 0.1-1% for north Sulawesi, Seram and Flores. The results of this national-scale hazard assessment provide evidence for disaster managers to prioritise regions for risk mitigation activities and/or more detailed hazard or risk assessment.

A~probabilistic tsunami hazard assessment for Indonesia

Science.gov (United States)

Horspool, N.; Pranantyo, I.; Griffin, J.; Latief, H.; Natawidjaja, D. H.; Kongko, W.; Cipta, A.; Bustaman, B.; Anugrah, S. D.; Thio, H. K.

2014-05-01

Probabilistic hazard assessments are a fundamental tool for assessing the threats posed by hazards to communities and are important for underpinning evidence based decision making on risk mitigation activities. Indonesia has been the focus of intense tsunami risk mitigation efforts following the 2004 Indian Ocean Tsunami, but this has been largely concentrated on the Sunda Arc, with little attention to other tsunami prone areas of the country such as eastern Indonesia. We present the first nationally consistent Probabilistic Tsunami Hazard Assessment (PTHA) for Indonesia. This assessment produces time independent forecasts of tsunami hazard at the coast from tsunami generated by local, regional and distant earthquake sources. The methodology is based on the established monte-carlo approach to probabilistic seismic hazard assessment (PSHA) and has been adapted to tsunami. We account for sources of epistemic and aleatory uncertainty in the analysis through the use of logic trees and through sampling probability density functions. For short return periods (100 years) the highest tsunami hazard is the west coast of Sumatra, south coast of Java and the north coast of Papua. For longer return periods (500-2500 years), the tsunami hazard is highest along the Sunda Arc, reflecting larger maximum magnitudes along the Sunda Arc. The annual probability of experiencing a tsunami with a height at the coast of > 0.5 m is greater than 10% for Sumatra, Java, the Sunda Islands (Bali, Lombok, Flores, Sumba) and north Papua. The annual probability of experiencing a tsunami with a height of >3.0 m, which would cause significant inundation and fatalities, is 1-10% in Sumatra, Java, Bali, Lombok and north Papua, and 0.1-1% for north Sulawesi, Seram and Flores. The results of this national scale hazard assessment provide evidence for disaster managers to prioritise regions for risk mitigation activities and/or more detailed hazard or risk assessment.

Mitigation of landslide area around railway tunnel, South Sumatra Province, Indonesia

Science.gov (United States)

Toha, M. Taufik; Setiabudidaya, Dedi; Komar, Syamsul; Bochori, Ghadafi, Moamar A.; Adiwarman, Mirza; Rahim, S. E.

2017-09-01

Adequate and safe railway line infrastructures as well as facilities are required to support the rail transport system in South Sumatra. The slope stability along railway line of Lahat-Lubuk Linggau South Sumatra were studied during landslide that occured on January 23th, 2016. The landslide occurred on the mouth of railway tunnel in Gunung Gajah Village, Lahat District that causing the railway transportation system had to be stopped for a few days. A comprehensive research was conducted to analyze the causes of the landslide and to identify other landslide risky areas along the railway line Lahat-Lubuk Linggau. The research activities included surveying, sampling, laboratory testing, investigating condition of geology, geotechnics, hydrogeology/hydrology, morphology and land use. The factors that cause landslide in the past studies were found to be morphology, structural geology, physical and mechanical characteristics, hydrogeology, hydrology, external forces (train vibration, earthquake). Results back analysis of slope stability when the landslide occurred showed that the value Safety Factor (SF) = 1, angle of friction = 0°, and cohesion = 0.49 kg/cm2 (49 kPa). Based on the observation and analysis of the condition of the morphology and orientation of the structure of the rock layers, there was a location prone to landslide (labile) in the surrounding area of the landslide. Mitigations to potential landslide in adjacent area were building a retaining wall, draining channels, and shortcrete at the rock wall after landslides and maintaining the land use around the slopes.

Tsunamis as geomorphic crises: Lessons from the December 26, 2004 tsunami in Lhok Nga, West Banda Aceh (Sumatra, Indonesia)

Science.gov (United States)

Paris, Raphaël; Wassmer, Patrick; Sartohadi, Junun; Lavigne, Franck; Barthomeuf, Benjamin; Desgages, Emilie; Grancher, Delphine; Baumert, Philippe; Vautier, Franck; Brunstein, Daniel; Gomez, Christopher

2009-03-01

Large tsunamis are major geomorphic crises, since they imply extensive erosion, sediment transport and deposition in a few minutes and over hundreds of kilometres of coast. Nevertheless, little is known about their geomorphologic imprints. The December 26, 2004 tsunami in Sumatra (Indonesia) was one of the largest and deadliest tsunamis in recorded human history. We present a description of the coastal erosion and boulder deposition induced by the 2004 tsunami in the Lhok Nga Bay, located to the West of Banda Aceh (northwest Sumatra). The geomorphological impact of the tsunami is evidenced by: beach erosion (some beaches have almost disappeared); destruction of sand barriers protecting the lagoons or at river mouths; numerous erosion escarpments typically in the order of 0.5-1.5 m when capped by soil and more than 2 m in dunes; bank erosion in the river beds (the retreat along the main river is in the order of 5-15 m, with local retreats exceeding 30 m); large scars typically 20-50 cm deep on slopes; dislodgement of blocks along fractures and structural ramps on cliffs. The upper limit of erosion appears as a continuous trimline at 20-30 m a.s.l., locally reaching 50 m. The erosional imprints of the tsunami extend to 500 m from the shoreline and exceed 2 km along riverbeds. The overall coastal retreat from Lampuuk to Leupung was 60 m (550,000 m 2) and locally exceeded 150 m. Over 276,000 m 3 of coastal sediments were eroded by the tsunami along the 9.2 km of sandy coast. The mean erosion rate of the beaches was ~ 30 m 3/m of coast and locally exceeded 80 m 3/m. The most eroded coasts were tangent to the tsunami wave train, which was coming from the southwest. The fringing reefs were not efficient in reducing the erosional impact of the tsunami. The 220 boulders measured range from 0.3 to 7.2 m large (typically 0.7-1.5 m), with weights from over 50 kg up to 85 t. We found one boulder, less than 1 m large, at 1 km from the coastline, but all the others were

Recent progress of geological investigations in Indonesia

Science.gov (United States)

Prijosoesilo, Purnomo; Sunarya, Yaya; Wahab, A.

Geologically, the Indonesian archipelago was formed as a result of the interaction and collision of the gigantic crustal blocks, i.e. the Eurasian, Indian, Australian and the Pacific plates. This process caused the formation of extensively distributed ultrabasic rocks in Eastern Indonesia, containing rich mineral resources. In Western Indonesia most ore bodies found are associated with the active volcano-plutonic arc or the stable mass of the Sunda Shelf. There are 60 known Tertiary sedimentary basins in Indonesia and only 36 of them have been "failry" explored, of which 14 basins have had hydrocarbon commercial production. Most of the hydrocarbon exploration and production during the last 100 years have been carried out in Western Indonesia. Many of the "unexplored" basins in Indonesia are located in the offshore areas with water depth over 200 m. Coal and geothermal resources are mostly found in Western Indonesia, particularly Sumatra, Java and Kalimantan. Coal production in 1990 has reached 11 million tons. The steady growth of production was primarily due to the establishment of the coal contract agreement with foreign contractors as well as the re-growth of the State coal mines in Bukit Asam and Sawahlunto, Sumatra. Aside from coal, geothermal is one of the alternative energy resources that have been developed in recent years. From some 16,000 MW resources potential estimated, presently only 140 MW geothermal generating power units have been commercially put on production in Kamojang, West Java. The most important minerals mined in Indonesia are tin (Sn), nickel (Ni), copper (Cu) and bauxite. Most of the gold (Au) and silver (Ag) production are mined in association with copper (Cu) such as those in Tembagapura, Irian Jaya, with the exception of a few epithermal gold mines in other areas in the country. Between 1984 and 1990, Indonesia produced around 1.3-1.5 MMBPD crude oil and condensate plus 1.6-2.2 TSCF natural gas. Most of the natural gas production was

Jambak Jambu Kalko: Nature conservation management of the Serampas of Jambi, Sumatra

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BAMBANG HARIYADI

2012-01-01

Full Text Available Hariyadi B. 2012. Jambak Jambu Kalko: Nature conservation management of the Serampas of Jambi, Sumatra. Biodiversitas 13: 40-45. Serampas is an indigenous group that still inhabits forested areas around the Kerinci Seblat National Park (KSNP in the island of Sumatra, Indonesia. The group has occupied the area since several centuries ago, long before the KSNP was officially proclaimed as a national park. The blending of local natural conditions, socio-cultural setting and cosmology has gradually produced a number of local wisdoms and practices to manage the local natural resources. The Serampas traditional resource management practices were not only friendly to the environment, but also encourage the more equitable distribution of natural resources among the members of the Serampas community. Jambak jambu kalko is literally means a list of locally important perennial fruit tree species protected by the Serampas customary system. Beyond the jambak jambu kalko the Serampas also recognize customs, traditions, and values that have important role in managing the local natural resources.

Biological control of Black Pod Disease and Seedling Blight of cacao caused by Phytophthora Species using Trichoderma from Aceh Sumatra

Science.gov (United States)

The cocoa tree, Theobroma cacao L., suffers large yield losses in Aceh Indonesia to the disease black pod rot, caused by Phytophthora spp. Despite having the largest area under cacao production in Sumatra, farmers in the Aceh region have low overall production because of losses to insect pests and b...

16,000 Years of Tropical Eastern Ocean Climate Variability Recorded in a Speleothem From Sumatra, Indonesia

Science.gov (United States)

Wurtzel, J. B.; Abram, N.; Hantoro, W. S.; Rifai, H.; Hellstrom, J. C.; Heslop, D.; Troitzsch, U.; Eggins, S.

2015-12-01

Holocene climate variability in the Indo-Pacific has largely been inferred from sediment cores primarily from the central and eastern Warm Pool region. A limited number of speleothem oxygen-isotope records have provided decadally-resolved time-series of past rainfall variability over the central Indo-Pacific Warm Pool region, however no records currently exist for the Indian Ocean sector of the IPWP. Here we present the first continuous, high-resolution (~15year) speleothem record from the eastern tropical Indian Ocean, collected from central western Sumatra, Indonesia. Petrographic and geochemical analysis reveals that the sample is primarily composed of aragonite but is punctuated by intervals of primary calcite growth. In addition to Raman spectroscopy, trace element analysis by laser ablation ICP-MS reveals strongly antiphased behaviour between magnesium and strontium, attributed to the strong preference of those elements for the calcite and aragonite lattices, respectively. This relationship is utilized to develop a quantitative correction for the stable isotope fractionation offset between the two calcium carbonate polymorphs identified in the speleothem. The corrected oxygen isotope record shows a rapid transition from drier conditions during the Younger Dryas (YD) into a wetter Holocene, similar in timing and pattern to that recorded in Dongge Cave, China. This is strikingly different from other IPWP speleothem records, which show no YD or a wetter YD, suggesting that different mechanisms may be controlling rainfall amount in the eastern tropical Indian Ocean. These disparate responses are further explored through proxy-model comparison.

Challenges in developing e-government for good governance in North Sumatra

Science.gov (United States)

Siahaan, AY

2017-01-01

E-government as one form of public administration reform in Indonesia is increasingly related to the pursuance of good governance. This paper examines the relationship between of e-government and good governance by utilizing the case study design on the implementation of e-procurement in North Sumatra. It reveals centrality of local politics and business culture in understanding resistances of both local government officials and local business which creates loopholes’ for the practice of ‘bad governance’ in all phases of e-procurement in North Sumatra province. Data transparency does not equate and guarantee the realization of good governance. Public knowledge and understanding on government decision making processes and accountability (process and policy transparency) are central to achieve good governance through e-procurement. E-procurement system does not automatically change organizational and working culture of the implementers and suppliers. This paper provides insight to the attitude and the perception of private sector engage in e-procurement towards government in implementing e-government. Resistance, digital divide and local politics interrelatedly obstruct the realization of pursuing good governance through e-procurement.

Exploring Teacher Strategies in Teaching Descriptive Writing in Indonesia

Science.gov (United States)

Suriyanti, Sufatmi; Yaacob, Aizan

2016-01-01

Purpose: This paper is the outcome of a study which examined teacher strategies in teaching descriptive writing to junior high school students in Delitua, North Sumatra, Indonesia. The study was based on two questions: 1) What are the teaching strategies used by EFL teachers in teaching descriptive writing? 2) To what extent did the descriptive…

Research of small quaternary AChE inhibitors as pretreatment of OP poisoning

International Nuclear Information System (INIS)

Musilek, K.; Komloova, M.; Holas, O.; Opletalova, V.; Pohanka, M.; Kuca, K.

2009-01-01

Small quaternary AChE inhibitors are used (e.g. pyridostigmine) or scoped (e.g. SAD-128) for pretreatment against organophosphate intoxication [1]. The pretreatment is based on competitive inhibition of AChE prior to organophosphate (OP) poisoning. Consequently, the OP can not influence the inhibited AChE and is degraded by other esterases. Although various competitive inhibitors are used globally, pyridostigmine still remains the most broaden. Its side effects including gastrointestinal effects (nausea, intestinal obstruction), increased bronchial secretion, cardiac arrhythmia or cholinergic crisis are well described. Moreover, some bisquaternary competitive inhibitors (e.g. SAD-128) were used to decrease lethal effects of OP poisoning in vivo. The further studies dealing with SAD-128 showed its increased ability to interact with brain muscarinic acetylcholine receptors as allosteric inhibitors [2]. The small molecules derived from quaternized pyridine, quinoline and isoquinoline were designed as AChE inhibitors. Their ability to inhibit AChE or BChE was determined in vitro using IC50. The IC50 data were compared within each group of compounds with emphasis on selectivity AChE versus BChE. The overall study will be presented. The work was supported by Ministry of Defence of Czech Republic No. OVUOFVZ200805.(author)

The drug sensitivity and transmission dynamics of human malaria on Nias Island, North Sumatra, Indonesia.

Science.gov (United States)

Fryauff, D J; Leksana, B; Masbar, S; Wiady, I; Sismadi, P; Susanti, A I; Nagesha, H S; Syafruddin; Atmosoedjono, S; Bangs, M J; Baird, J K

2002-07-01

Nias Island, off the north-western coast of Sumatra, Indonesia, was one of the first locations in which chloroquine-resistant Plasmodium vivax malaria was reported. This resistance is of particular concern because its ancient megalithic culture and the outstanding surfing conditions make the island a popular tourist destination. International travel to and from the island could rapidly spread chloroquine-resistant strains of P. vivax across the planet. The threat posed by such strains, locally and internationally, has led to the routine and periodic re-assessment of the efficacy of antimalarial drugs and transmission potential on the island. Active case detection identified malaria in 124 (17%) of 710 local residents whereas passive case detection, at the central health clinic, confirmed malaria in 77 (44%) of 173 cases of presumed 'clinical malaria'. Informed consenting volunteers who had malarial parasitaemias were treated, according to the Indonesian Ministry of Health's recommendations, with sulfadoxine-pyrimethamine (SP) on day 0 (for P. falciparum) or with chloroquine (CQ) on days 0, 1 and 2 (for P. vivax). Each volunteer was then monitored for clinical and parasite response until day 28. Recurrent parasitaemia by day 28 treatment was seen in 29 (83%) of the 35 P. falciparum cases given SP (14, 11 and four cases showing RI, RII and RIII resistance, respectively). Recurrent parasitaemia was also observed, between day 11 and day 21, in six (21%) of the 28 P. vivax cases given CQ. Although the results of quantitative analysis confirmed only low prevalences of CQ-resistant P. vivax malaria, the prevalence of SP resistance among the P. falciparum cases was among the highest seen in Indonesia. When the parasites present in the volunteers with P. falciparum infections were genotyped, mutations associated with pyrimethamine resistance were found at high frequency in the dhfr gene but there was no evidence of selection for sulfadoxine resistance in the dhps gene

Measurement of acetylcholinesterase (AChE) activity in living brain by positron emission tomography (PET)

Energy Technology Data Exchange (ETDEWEB)

Irie, Toshiaki [National Inst. of Radiological Sciences, Chiba (Japan)

1999-07-01

Central cholinergic neuronal system has been known to be related to learning and memory, and its deficit is found in the brain of Alzheimer's disease (AD) and other degenerative disorders. Postmortem studies have shown that acetylcholinesterase (AChE), one of biochemical markers of central cholinergic nerve system, is consistently reduced in the cerebral cortex of patients with Alzheimer's disease (AD). Non-invasive mapping and/or measuring AChE activity in the living brain by positron emission tomography (PET) would be a useful tool for assessment of cholinergic dysfunction in AD and other disorders, and provide a direct method for validation of therapeutic efficacy of drugs, AChE inhibitors. We have challenged to measure AChE activity using tracers of substrate type, radiolabelled acetylcholine analogs, which are lipophilic enough to go across blood brain barrier and are metabolically trapped by AChE in the brain. The analogs designed, N-methylpiperidyl esters, were evaluated in terms of their metabolic rate and specificity against AChE. Studies examining the response to AChE activity showed metabolic accumulation of some analogs responded well to changes in cortical AChE activity in an animal model of AD. The study was further applied to living human by PET using [{sup 11}C]N-methylpiperidyl-4-acetate (MP4A), which was chosen on the basis of its reactivity and specificity suitable for the human cortical AChE. Regional cerebral metabolic rate of MP4A reflecting AChE activity was quantitatively determined using three compartment model analysis of dynamic PET data and the arterial input function obtained by TLC-radioluminography or plasma samples. The kinetic analyses showed that AChE activities estimated were well agree with those of postmortem examination in cerebral cortices and thalamus in healthy subjects, and that there was significant reduction of cortical AChE activity in patients with AD. The results suggest feasibility of the present method for

Centrally Acting Oximes in Reactivation of Tabun-Phosphoramidated AChE

Science.gov (United States)

Kovarik, Zrinka; Maček, Nikolina; Sit, Rakesh K.; Radić, Zoran; Fokin, Valery V.; Sharpless, K. Barry; Taylor, Palmer

2012-01-01

Organophosphates (OP) inhibit acetylcholinesterase (AChE, E.C.3.1.1.7), both in peripheral tissues and central nervous system (CNS), causing adverse and sometimes fatal effects due to the accumulation of neurotransmitter acetylcholine (ACh). The currently used therapy, focusing on the reactivation of inhibited AChE, is limited to peripheral tissues because commonly used quaternary pyridinium oxime reactivators do not cross the blood brain barrier (BBB) at therapeutically relevant levels. A directed library of thirty uncharged oximes that contain tertiary amine or imidazole protonable functional groups that should cross the BBB as unionized species was tested as tabun-hAChE conjugate reactivators along with three reference oximes: DAM (diacetylmonoxime), MINA (monoisonitrosoacetone), and 2-PAM. The oxime RS150D [N-((1-(3-(2-((hydroxyimino)methyl)-1H-imidazol-1-yl)propyl)-1H-1,2,3-triazol-4-yl)methyl)benzamide] was highlighted as the most promising reactivator of the tabun-hAChE conjugate. We also observed that oximes RS194B [N-(2-(azepan-1-yl)ethyl)-2-(hydroxyimino)acetamide] and RS41A [2-(hydroxyimino)-N-(2-(pyrrolidin-1-yl)ethyl)acetamide], which emerged as lead uncharged reactivators of phosphylated hAChE with other OPs (sarin, cyclosarin and VX), exhibited only moderate reactivation potency for tabun inhibited hAChE. This implies that geometry of oxime access to the phosphorus atom conjugated to the active serine is an important criterion for efficient reactivation, along with the chemical nature of the conjugated moiety: phosphorate, phosphonate, or phosphoramidate. Moreover, modification of the active center through mutagenesis enhances the rates of reactivation. The phosphoramidated-hAChE choline-binding site mutant Y337A showed three-times enhanced reactivation capacity with non-triazole imidazole containing aldoximes (RS113B, RS113A and RS115A) and acetamide derivative (RS194B) than with 2PAM. PMID:22960624

Islamic Puritanism Movements in Indonesia as Transnational Movements

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Benny Baskara

2017-04-01

Full Text Available Islamic puritanism movements are the movements compelling to return to the teachings of Quran and Sunnah, as the pure teachings of Islam and abandon even abolish other teachings outside the teachings of Quran and Sunnah. The movements of Islamic puritanism can be considered as transnational movements because they spread their teachings and ideologies, create organizations, networks, and provide financial supports across nations. This paper describes Islamic puritanism movements in Indonesia and their transnational connections. Some Islamic puritanism movements in Indonesia can be considered as part of Islamic transnational movements, in which most of the movements are centered in the Middle East. In Indonesia, Islamic puritanism movements firstly appeared in the beginning of the nineteenth century, called Padri movement in West Sumatra. It was then continued to the emergence of Islamic organizations in the twentieth century. Recently, Islamic puritanism movements in Indonesia mostly take form as Salafism-Wahabism movements.

Contribution of forest restoration to rural livelihoods and household income in Indonesia

DEFF Research Database (Denmark)

Widianingsih, Nayu Nuringdati; Theilade, Ida; Pouliot, Mariéve

2016-01-01

restoration area in Sumatra, Indonesia. Survey data were collected on 268 households, with a four-month recall period and three repeat visits to each selected household within a year. Random sampling was applied to select households in five villages and five Batin Sembilan (indigenous) semi-nomadic groups...

Phylogeography of the current rabies viruses in Indonesia

Science.gov (United States)

Dibia, I Nyoman; Sumiarto, Bambang; Susetya, Heru; Putra, Anak Agung Gde; Scott-Orr, Helen

2015-01-01

Rabies is a major fatal zoonotic disease in Indonesia. This study was conducted to determine the recent dynamics of rabies virus (RABV) in various areas and animal species throughout Indonesia. A total of 27 brain samples collected from rabid animals of various species in Bali, Sumatra, Kalimantan, Sulawesi, Java, and Flores in 2008 to 2010 were investigated. The cDNA of the nucleoprotein gene from each sample was generated and amplified by one-step reverse transcription-PCR, after which the products were sequenced and analyzed. The symmetric substitution model of a Bayesian stochastic search variable selection extension of the discrete phylogeographic model of the social network was applied in BEAST ver. 1.7.5 software. The spatial dispersal was visualized in Cartographica using Spatial Phylogenetic Reconstruction of Evolutionary Dynamics. We demonstrated inter-island introduction and reintroduction, and dog was found to be the only source of infection of other animals. Ancestors of Indonesian RABVs originated in Java and its descendants were transmitted to Kalimantan, then further to Sumatra, Flores, and Bali. The Flores descendent was subsequently transmitted to Sulawesi and back to Kalimantan. The viruses found in various animal species were transmitted by the dog. PMID:25643792

The assesment of flex blue implementation in Indonesia

International Nuclear Information System (INIS)

Sahala Maruli Lumbanraja

2014-01-01

Flex blue is a small power modular and light water cooled reactor. The reactor site is located at the bottom of the sea surface (off shore) and main control room on the ground. Hull that contains of the main reactor components is placed at a depth of 60-100 m in the bottom of the sea surface so that the safety and security system is quite high. NPP was developed by the DCNS-France to meet the electrical energy needs of the world. The purpose of this study was to study the pre-feasibility of Flex blue implementation in Indonesia based on technological factors, sea geographical conditions and regulatory. The methodology used is to study a variety of literature study on NPP Flex blue technology, geographic conditions, and regulatory systems in Indonesia. In this study, location of potential sites are on the east coast of the island of Sumatra, Java's northern coast, the coast of the Borneo island and surrounding coastal islands between the east of the Sumatra island, northern Java and Borneo, however in terms of regulation, this technology could not be implemented. (author)

Maturity analysis of the innovation system in the livestock industries of West Sumatra, Indonesia

Science.gov (United States)

Suresti, A.; Dinata, U. G. S.; Wati, R.

2018-02-01

The main objective of this study was to analyse the ANIS of Livestock industry in West Sumatera according to its main determinants. This research aims to know and understand the maturity level of the regional innovationsystem of West Sumatra livestock industries, including recommendation for improvements. The maturity level of the regional innovation system was analyzed with the ANIS method by using an opinion survey to some experts from businessmen, government and universities. This expert opinion survey was conducted to measure expert perceptions on the implementations of determinants of west Sumatera regional innovations systems on livestock industries on macro level (innovations policy), mezzo level (innovation institutions and programs) and micro level (innovation capacity). By using Likert method, the result showed maturity level for the West Sumatra livestock industries innovation system was still develop. This is caused by low maturity in the macro and meso determinants which are at the central and regional government side. This research result may be useful as recommendations for the government for improving the maturity level and may be a basic for incoming researches to identify regional innovation system determinants with low maturity to improve.

Preliminary Screening a Potential AChE Inhibitor in Thai Golden Shower (Leguminosae mimosoideae Extracts

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Jakkaphun Nanuam

2013-07-01

Full Text Available Pesticides are used to control pests of agriculture products in many countries including Thailand. Since they can exert harmful effects not only on target pests but also on other useful organisms, alternative agents are investigated. We studied the capacity of the Thai golden shower (Leguminosae mimosoideae extracts (root and pod to inhibit acetyl cholinestarese (AChE in the golden apple snail (Pomacea canaliculata as a pest representative. The results showed that the percentage of AChE inhibition increased with increasing in exposure times. The inhibition expressed the same trend in both male and female apple snails. AChE inhibition was higher in extracts from root than from pod. Chromatography-Mass Spectrometer (GC-MS chromatograms demonstrated anthraquinone, an AChE inhibitor, in extracts of golden shower. Our data indicate that a potential AChE inhibitor tends to accumulate more in the root part than in the pod.

Report on the FY 1989 potential survey of overseas coal development. Coal fields in Indonesia; 1989 nendo kaigaitan kaihatsu kanosei chosa hokokusho. Indonesia kyowakoku kaku tanden

Energy Technology Data Exchange (ETDEWEB)

NONE

1989-12-01

This survey is aimed at acquiring the basic data required for judging a possibility of development/import of steam coal in Indonesia (west of Java, north of Sumatra and west of Sumatra). Areas for survey are Meulaboh coal field in north Sumatra, Ombilin III area in West Sumatra, and Bayah coal field in West Java. The survey includes the field survey to grasp the situation of coal seam existence, coal quality, coal amount, etc. and activities for collecting the related data and information from the organizations concerned. The Meulaboh coal field has a technical possibility of open pit mining of medium scale. However, the heating value is extremely low, around 4,300 kcal/kg. Judging from this coal quality, there is no possibility of exporting it. It can be said that Ombilin coal is the world's top class steam coal. Accordingly, the demand can be expected both in export use and domestic use. As to Bayah coal, Bemmelen (1949) concluded that the coal was extremely excellent in quality, but had great disadvantages such as thin coal seam, discontinuity, and complicated geological structure. To date, the conclusion has been unchanged. (NEDO)

Challenges for control of taeniasis/cysticercosis in Indonesia.

Science.gov (United States)

Suroso, Thomas; Margono, Sri S; Wandra, Toni; Ito, Akira

2006-01-01

Taeniasis/cysticercosis has been reported from several provinces of Indonesia: Papua (=former Irian Jaya), Bali, North Sumatra, East Nusa Tenggara, South East Sulawesi, Lampung, North Sulawesi, Jakarta, West Kalimantan, and East Java. The highest level of endemicity of taeniasis/cysticercosis has been found in Papua. Recent surveys in Jayawijaya District of Papua in 2000 and 2001 showed that 5 of 58 local people (8.6%) harbored the adult tapeworm, Taenia solium, whereas 44 of 96 people (45.8%), 50 of 71 pigs (70.4%), and 7 of 64 local dogs (10.9%) were seropositive for T. solium cysticercosis. Current surveys in Bali and Samosir District, North Sumatra during 2002-2005 revealed that Taenia saginata taeniasis has increased in incidence whereas T. solium cysticercosis is now rather rare compared to one-two decades ago in Bali. Taenia asiatica taeniasis is still common in Samosir District. Data from other provinces of Indonesia are very limited or unavailable. Control of these diseases is not a priority in the health or veterinary services, neither at central or local government levels. However, limited efforts toward control of the diseases have been implemented such as training of health personnel, community education on disease prevention, and provision of anthelminthics. A working group for control of the disease in Indonesia and an international collaboration have been established among Ministry of Health, Indonesia; University of Indonesia; and Asahikawa Medical College, Asahikawa, Japan since 1996. Future goals include implementation of active case finding (active surveillance) and treatment of tapeworm carriers, sustainable public health education, establishment of a system to check the quality of beef/pork and determine the distribution of infected animals and strengthening of laboratory capacity. Efforts to motivate provinces and districts should be implemented in developing the strategic plan to control of the disease. Given the considerable differences in

Natural AChE Inhibitors from Plants and their Contribution to Alzheimer's Disease Therapy.

Science.gov (United States)

Murray, Ana Paula; Faraoni, María Belén; Castro, María Julia; Alza, Natalia Paola; Cavallaro, Valeria

2013-07-01

As acetylcholinesterase (AChE) inhibitors are an important therapeutic strategy in Alzheimer's disease, efforts are being made in search of new molecules with anti-AChE activity. The fact that naturally-occurring compounds from plants are considered to be a potential source of new inhibitors has led to the discovery of an important number of secondary metabolites and plant extracts with the ability of inhibiting the enzyme AChE, which, according to the cholinergic hypothesis, increases the levels of the neurotransmitter acetylcholine in the brain, thus improving cholinergic functions in patients with Alzheimer's disease and alleviating the symptoms of this neurological disorder. This review summarizes a total of 128 studies which correspond to the most relevant research work published during 2006-2012 (1st semester) on plant-derived compounds, plant extracts and essential oils found to elicit AChE inhibition.

An annotated list of the species of the genus Corbicula from Indonesia (Mollusca: Corbiculidae)

NARCIS (Netherlands)

Djajasasmita, Machfudz

1977-01-01

The species of the genus Corbicula known from Indonesia are alphabetically listed and noted. Sixteen out of the 35 described species are considered valid, i.e. C. gustaviana, C. moltkiana, C. sumatrana, C. tobae and C. tumida from Sumatra; C. javanica, C. pulchella and C. rivalis from Java; C.

DISTRIBUTION AND INCIDENCE LEAF DISEASES OF BANANA IN SEVERAL BANANA PRODUCTION CENTERS IN NORTH SUMATRA, WEST SUMATRA BENGKULU AND WEST JAVA

Directory of Open Access Journals (Sweden)

Sahlan

2011-06-01

Full Text Available The research was aimed to determine the type, the distribution and the incidence of banana leaf diseases in several production centers in West Sumatra, Bengkulu, North Sumatra and West Java. Direct observations on banana orchards were conducted in some districts in Simalungun, Deli Serdang and Medan (North Sumatra, Tanah Datar, Limapuluh Kota, Agam, Pariaman and Pasaman (West Sumatra, Rejang Lebong and Kepahyang (Bengkulu, Sukabumi, Purwakarta and Subang (West Java from November to December 2006. Two banana orchards were randomly selected in each district. Plant population at the selected orchard was at least 100 plants. From each sampled orchard, if banana population consisted of similar or only one variety, 10 plants were randomly chosen according to wind direction. Meanwhile, when the banana varieties were varied, five plants were randomly selected. The result showed that Black Sigatoka and Eumusae leaf spot were found in West Sumatra, Bengkulu and North Sumatra at severity level of between 15 % to 62.31%, whilst speckle disease was mainly found in North Sumatra and in parts of West Sumatra at severity level of between 72,72% to 100% and 15 to 30%, respectively. Banana varieties that were primarily attacked by leaf diseases were Cavendish, Telor, Barangan and Emas.

Natural AChE Inhibitors from Plants and their Contribution to Alzheimer’s Disease Therapy

OpenAIRE

Murray, Ana Paula; Faraoni, María Belén; Castro, María Julia; Alza, Natalia Paola; Cavallaro, Valeria

2013-01-01

As acetylcholinesterase (AChE) inhibitors are an important therapeutic strategy in Alzheimer’s disease, efforts are being made in search of new molecules with anti-AChE activity. The fact that naturally-occurring compounds from plants are considered to be a potential source of new inhibitors has led to the discovery of an important number of secondary metabolites and plant extracts with the ability of inhibiting the enzyme AChE, which, according to the cholinergic hypothesis, increases the le...

Causes of low vision and blindness in rural Indonesia

Science.gov (United States)

Saw, S-M; Husain, R; Gazzard, G M; Koh, D; Widjaja, D; Tan, D T H

2003-01-01

Aim: To determine the prevalence rates and major contributing causes of low vision and blindness in adults in a rural setting in Indonesia Methods: A population based prevalence survey of adults 21 years or older (n=989) was conducted in five rural villages and one provincial town in Sumatra, Indonesia. One stage household cluster sampling procedure was employed where 100 households were randomly selected from each village or town. Bilateral low vision was defined as habitual VA (measured using tumbling “E” logMAR charts) in the better eye worse than 6/18 and 3/60 or better, based on the WHO criteria. Bilateral blindness was defined as habitual VA worse than 3/60 in the better eye. The anterior segment and lens of subjects with low vision or blindness (both unilateral and bilateral) (n=66) were examined using a portable slit lamp and fundus examination was performed using indirect ophthalmoscopy. Results: The overall age adjusted (adjusted to the 1990 Indonesia census population) prevalence rate of bilateral low vision was 5.8% (95% confidence interval (CI) 4.2 to 7.4) and bilateral blindness was 2.2% (95% CI 1.1 to 3.2). The rates of low vision and blindness increased with age. The major contributing causes for bilateral low vision were cataract (61.3%), uncorrected refractive error (12.9%), and amblyopia (12.9%), and the major cause of bilateral blindness was cataract (62.5%). The major causes of unilateral low vision were cataract (48.0%) and uncorrected refractive error (12.0%), and major causes of unilateral blindness were amblyopia (50.0%) and trauma (50.0%). Conclusions: The rates of habitual low vision and blindness in provincial Sumatra, Indonesia, are similar to other developing rural countries in Asia. Blindness is largely preventable, as the major contributing causes (cataract and uncorrected refractive error) are amenable to treatment. PMID:12928268

Cultural meanings of tuberculosis in Aceh Province, Sumatra.

Science.gov (United States)

Caprara, A; Abdulkadir, N; Idawani, C; Asmara, H; Lever, P; De Virgilio, G

2000-07-01

This paper shows how disease transmission and particularly what biomedicine calls tuberculosis are interpreted in the non-Western context of Aceh Province, Sumatra, Indonesia. It tries also to focus on factors influencing perceptions and health-seeking behaviors. Results show that what biomedicine calls TB is represented by a semantic network of illnesses. Parts of this network are clearly identified as transmissible while others are related to specific phenomena affecting the individual, such as terbuk (poisoning) or trouk (fatigue produced by hard work), and are not considered contagious. Forms of transmission are interpreted mostly through empirical and analogic categories. TB is attributed to four different aspects: (a) biomedical categories such as germ theory; (b) socio-economic conditions; (c) transgression of social rules; and (d) poisoning and the influences of supernatural powers. Health-seeking behaviors are related to the perceived causes of the disease, economic factors, and the accessibility of health services.

Soil nitrogen oxide fluxes from lowland forests converted to smallholder rubber and oil palm plantations in Sumatra, Indonesia

Science.gov (United States)

Hassler, Evelyn; Corre, Marife D.; Kurniawan, Syahrul; Veldkamp, Edzo

2017-06-01

Oil palm (Elaeis guineensis) and rubber (Hevea brasiliensis) plantations cover large areas of former rainforest in Sumatra, Indonesia, supplying the global demand for these crops. Although forest conversion is known to influence soil nitrous oxide (N2O) and nitric oxide (NO) fluxes, measurements from oil palm and rubber plantations are scarce (for N2O) or nonexistent (for NO). Our study aimed to (1) quantify changes in soil-atmosphere fluxes of N oxides with forest conversion to rubber and oil palm plantations and (2) determine their controlling factors. In Jambi, Sumatra, we selected two landscapes that mainly differed in texture but were both on heavily weathered soils: loam and clay Acrisol soils. Within each landscape, we investigated lowland forests, rubber trees interspersed in secondary forest (termed as jungle rubber), both as reference land uses and smallholder rubber and oil palm plantations as converted land uses. In the loam Acrisol landscape, we conducted a follow-on study in a large-scale oil palm plantation (called PTPN VI) for comparison of soil N2O fluxes with smallholder oil palm plantations. Land-use conversion to smallholder plantations had no effect on soil N-oxide fluxes (P = 0. 58 to 0.76) due to the generally low soil N availability in the reference land uses that further decreased with land-use conversion. Soil N2O fluxes from the large-scale oil palm plantation did not differ with those from smallholder plantations (P = 0. 15). Over 1-year measurements, the temporal patterns of soil N-oxide fluxes were influenced by soil mineral N and water contents. Across landscapes, annual soil N2O emissions were controlled by gross nitrification and sand content, which also suggest the influence of soil N and water availability. Soil N2O fluxes (µg N m-2 h-1) were 7 ± 2 to 14 ± 7 (reference land uses), 6 ± 3 to 9 ± 2 (rubber), 12 ± 3 to 12 ± 6 (smallholder oil palm) and 42 ± 24 (large-scale oil palm). Soil NO fluxes (µg N m-2 h-1) were -0.6 �

CORRELATION BETWEEN RESPECT, RESPONSIBILITY, INTERPERSONAL RELATIONSHIP, SUPERVISION, AND COMPENSATION TO THE PERFORMANCE OF OFFICIAL RECORDER AT STATE HOSPITALS BUKITTINGGI WEST-SUMATRA INDONESIA

Directory of Open Access Journals (Sweden)

Syukra Alhamda

2013-01-01

Full Text Available Objective: Primary survey was conducted on November 10, 2012 at The State Hospitals Bukittinggi, with randomly selected of 100 hospital medical records. There were incomplete contents of 61.66% and 48.33% of late files. This issue is very disturbing process for management of recording medical data, therefore, disrupting functions of medical recorders.Method: This study applied cross-sectionalstudy to determine the correlation between respect, responsibility, interpersonal relations, supervisionand compensation for the performance of official recorders at The State Hospitals Bukittinggi West-Sumatra Indonesia. Questionnaires from the subjects were proceed and computed by applying chisquare test.Results: The results showed that there were significant correlation between the performance of official award recorders (p = 0.003 and OR = 9.208, responsibilities (p = 0.012 and OR = 6.094, interpersonal (p = 0.0025 and OR = 5.417, performance of official (p = 0.012 and OR = 6.094, and compensation of official recorders (p = 0.025 and OR = 5.417 to recorders performance. Conclusion: In this research, we observed that there was a significant correlation between respect, responsibility, interpersonal relations, supervision and compensation to the performance of official recorders. A greater

Ecology, Epidemiology and Disease Management of Ralstonia syzygii in Indonesia.

Science.gov (United States)

Safni, Irda; Subandiyah, Siti; Fegan, Mark

2018-01-01

Ralstonia solanacearum species complex phylotype IV strains, which have been primarily isolated from Indonesia, Australia, Japan, Korea, and Malaysia, have undergone recent taxonomic and nomenclatural changes to be placed in the species Ralstonia syzygii . This species contains three subspecies; Ralstonia syzygii subsp. syzygii , a pathogen causing Sumatra disease of clove trees in Indonesia, Ralstonia syzygii subsp. indonesiensis , the causal pathogen of bacterial wilt disease on a wide range of host plants, and Ralstonia syzygii subsp. celebesensis , the causal pathogen of blood disease on Musa spp. In Indonesia, these three subspecies have devastated the cultivation of susceptible host plants which have high economic value. Limited knowledge on the ecology and epidemiology of the diseases has hindered the development of effective control strategies. In this review, we provide insights into the ecology, epidemiology and disease control of these three subspecies of Ralstonia syzygii .

Integrated study of geophysical and biological anomalies before earthquakes (seismic and non-seismic), in Austria and Indonesia

Science.gov (United States)

Straka, Wolfgang; Assef, Rizkita; Faber, Robert; Ferasyi, Reza

2015-04-01

Earthquakes are commonly seen as unpredictable. Even when scientists believe an earthquake is likely, it is still hard to understand the indications observed, as well as their theoretical and practical implications. There is some controversy surrounding the concept of using animals as a precursor of earthquakes. Nonetheless, several institutes at University of Natural Resources and Life Sciences, and Vienna University of Technology, both Vienna, Austria, and Syiah Kuala University, Banda Aceh, as well as Terramath Indonesia, Buleleng, both Indonesia, cooperate in a long-term project, funded by Red Bull Media House, Salzburg, Austria, which aims at getting some decisive step forward from anecdotal to scientific evidence of those interdependencies, and show their possible use in forecasting seismic hazard on a short-term basis. Though no conclusive research has yet been published, an idea in this study is that even if animals do not respond to specific geophysical precursors and with enough notice to enable earthquake forecasting on that basis, they may at least enhance, in conjunction with other indications, the degree of certainty we can get of a prediction of an impending earthquake. In Indonesia, indeed, before the great earthquakes of 2004 and 2005, ominous geophysical as well as biological phenomena occurred (but were realized as precursors only in retrospect). Numerous comparable stories can be told from other times and regions. Nearly 2000 perceptible earthquakes (> M3.5) occur each year in Indonesia. Also, in 2007, the government has launched a program, focused on West Sumatra, for investigating earthquake precursors. Therefore, Indonesia is an excellent target area for a study concerning possible interconnections between geophysical and biological earthquake precursors. Geophysical and atmospheric measurements and behavioral observation of several animal species (elephant, domestic cattle, water buffalo, chicken, rat, catfish) are conducted in three areas

Ceratocystis larium sp. nov., a new species from Styrax benzoin wounds associated with incense harvesting in Indonesia

NARCIS (Netherlands)

Wyk, van M.; Wingfield, B.D.; Clegg, P.A.; Wingfield, M.J.

2009-01-01

Styrax benzoin trees, native to the island Sumatra, Indonesia are wounded to produce resin that is collected and burned as incense. These wounds on trees commonly develop into expanding cankers that lead to tree death. The aim of this study was to consider whether Ophiostomatoid fungi, typically

An Investigation of Seismicity for the West Sumatra Region Indonesia

Science.gov (United States)

Syafriani, S.

2018-04-01

The purpose of this research was to investigate the seismicity of the West Sumatra region in the coordinates area of 94° E – 104° E and 2° N - 4° S. Guttenberg-Richer magnitude-frequency relation and seismic risk have been computed. Historical data of earthquakes used from year of 1970 to 2017 with magnitude higher than 4. The study area was divided into 8 sub-regions based on seismotectonic characteristics, plate tectonic and geological models. The determination of seismotectonic characteristics was based on the level of seismic activity in a region (a value) and rock stress condition (b value). High a value was associated with high seismic activity, whereas high b values were associated with low stress rock conditions, and vice versa. Based on the calculation results, a and b values were obtained in the interval of 5.5-11.3 and 0.7-2. The highest b value was obtained in the sub region 5 (Nias islands), while the lowest b value was obtained in sub region 7 (the Mentawai islands). The sub region 7, Mentawai Islands was indicated as the seismic risk potential areas.

GPS water level measurements for Indonesia's Tsunami Early Warning System

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T. Schöne

2011-03-01

Full Text Available On Boxing Day 2004, a severe tsunami was generated by a strong earthquake in Northern Sumatra causing a large number of casualties. At this time, neither an offshore buoy network was in place to measure tsunami waves, nor a system to disseminate tsunami warnings to local governmental entities. Since then, buoys have been developed by Indonesia and Germany, complemented by NOAA's Deep-ocean Assessment and Reporting of Tsunamis (DART buoys, and have been moored offshore Sumatra and Java. The suite of sensors for offshore tsunami detection in Indonesia has been advanced by adding GPS technology for water level measurements.

The usage of GPS buoys in tsunami warning systems is a relatively new approach. The concept of the German Indonesian Tsunami Early Warning System (GITEWS (Rudloff et al., 2009 combines GPS technology and ocean bottom pressure (OBP measurements. Especially for near-field installations where the seismic noise may deteriorate the OBP data, GPS-derived sea level heights provide additional information.

The GPS buoy technology is precise enough to detect medium to large tsunamis of amplitudes larger than 10 cm. The analysis presented here suggests that for about 68% of the time, tsunamis larger than 5 cm may be detectable.

Provenance of sediments from Sumatra, Indonesia - Insights from detrital U-Pb zircon geochronology, heavy mineral analyses and Raman spectroscopy

Science.gov (United States)

Liebermann, C.; Hall, R.; Gough, A.

2017-12-01

The island of Sumatra is situated at the southwestern margin of the Indonesian archipelago. Although it is the sixth largest island in the world, the geology of the Sumatra sedimentary basins and their underlying basement is relatively poorly understood in terms of their provenance. This work is a multi-proxy provenance study utilizing U-Pb detrital zircon dating by LA-ICP-MS combined with optical and Raman spectroscopy-based heavy mineral analysis. It will help to unravel the stratigraphy of Sumatra, contribute to paleogeographic reconstruction of western SE Asia, and aid a wider understanding of Sumatran petroleum plays. Thin section analyses, heavy mineral assemblages, and >3500 concordant U-Pb zircon ages, from samples acquired during two fieldwork seasons indicate a mixed provenance for Cenozoic sedimentary formations, including both local igneous sources and mature basement rocks. Characteristic Precambrian zircon age spectra are found in all analysed Cenozoic sedimentary strata. These can be correlated with zircon age populations found in Sumatran basement rocks; Neoproterozoic and Mesoproterozoic age groups are dominant (c. 500-600 Ma, c. 850-1000 Ma, c. 1050-1200 Ma). Paleoproterozoic to Archaean zircons occur as minor populations. The Phanerozoic age spectra of the Cenozoic formations are characterised by distinct Carboniferous, Permo-Triassic, and Jurassic-Cretaceous zircon populations. Permo-Triassic zircons are interpreted to come from granitoids in the Malay peninsula or Sumatra itself. Eocene to Lower Miocene strata are characterised by ultrastable heavy minerals such as zircon, tourmaline, and rutile, which together with garnet, suggest the principal sources were igneous and metamorphic basement rocks. Cenozoic zircons appear only from the Middle Miocene onwards. This change is interpreted to indicate a new contribution from a local volcanic arc, and is supported by the occurrence of unstable heavy minerals such as apatite and clinopyroxene, and the

CESTODES IN MAN IN INDONESIA

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Sri S. Margono

2012-09-01

Full Text Available Cestodes are found endemic in certain areas of Indonesia. The most common cestodes found are Taenia saginata and Taenia solium. Eggs of Taenia are found in stool samples during surveys in Irian Jaya (2-9 %, Nusa Tenggara Timur (7 %, Bali and resettlement areas of people from Bali (0,4 - 3,3%. Interviews, with questions concerning expelled segments, recovered a prevalence of 9,5 % in inhabitants of the island of Samosir (North Sumatra and 2 % in the people of 6 villages in Abiansemal (Bali. Cases are also reported from Jakarta. Hymenolepis nana (0,2 -1% and Hymenolepis diminuta (0,4 % are rarely found in surveys. A case of hyperinfection with H. nana has been reported in Jakarta in 1968. Occasionally there are reports of infections with Dipylidium caninum, Raillietina madagascariensis, Bertiella studeri and sparganum. Report on treatment of taeniasis in Indonesia mentioned the use of atabrine, mebendazole, bithionol and praziquantel with different results.

Mapping and analysis land-use and land-cover changes during 1996-2016 in Lubuk Kertang mangrove forest, North Sumatra, Indonesia

Science.gov (United States)

Basyuni, M.; Fitri, A.; Harahap, Z. A.

2018-03-01

Mangrove forest plays a significant role for biogeochemical carbon cycle in the context of climate change along the tropical coastal area. The present study analyzed the land-use and land-cover changes from 1996, 2006 and 2016 in Lubuk Kertang mangrove forest, Langkat, North Sumatra, Indonesia. Mangrove diversity in Lubuk Kertang consists of fifteen species, Acanthus ilicifolius, Avicennia marina, A. lanata, A. officinalis, Bruguiera gymnorrhiza, B. sexangula, Ceriops tagal, Excoecaria agallocha, Lumnitzera racemosa, L. littorea, R. apiculata, R. mucronata, Scyphiphora hydrophyllacea, Sonneratia caseolaris, and Xylocarpus granatum. The land use/land cover consists of seven classes namely, mangrove forest, river, residential, paddy field, oil palm plantation, aquaculture, and open space area. A land use change matrix showed that the decrease of mangrove forest 109.4 ha from 1996-2006 converted to aquaculture 51.5 ha (47.1%). By contrast, mangrove lost 291.2 ha during 2006-2016, with main driver deforestation was oil palm plantation 128.1 ha (44%). During twenty years mangrove forest has been lost more than 400.4 ha, which is equal to 20.02 ha/year. On the other hand, oil palm plantation and aquaculture have been increased 155.3 ha and 114.1 ha during 1996-2016, respectively, suggested that both land-uses are mainly responsible for mangrove deforestation. These data are likely to contribute towards coastal management planning and practice and mitigating actions for emission reduction scenario.

Interactions of AChE with Aβ Aggregates in Alzheimer’s Brain: Therapeutic Relevance of IDN 5706

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Francisco Javier Carvajal

2011-09-01

Full Text Available Acetylcholinesterase (AChE; EC 3.1.1.7 plays a crucial role in the rapid hydrolysis of the neurotransmitter acetylcholine, in the central and peripheral nervous system and might also participate in non-cholinergic mechanism related to neurodegenerative diseases. Alzheimer’s disease (AD is a neurodegenerative disorder characterized by a progressive deterioration of cognitive abilities, amyloid-β peptide (Aβ accumulation and synaptic alterations. We have previously shown that AChE is able to accelerate the Aβ peptide assembly into Alzheimer-type aggregates increasing its neurotoxicity. Furthermore, AChE activity is altered in brain and blood of Alzheimer’s patients. The enzyme associated to amyloid plaques changes its enzymatic and pharmacological properties, as well as, increases its resistant to low pH, inhibitors and excess of substrate. Here, we reviewed the effects of IDN 5706, a hyperforin derivative that has potential preventive effects on the development of AD. Our results show that treatment with IDN5706 for 10 weeks increases brain AChE activity in seven month-old double transgenic mice (APPswe - PS1 and decreases the content of AChE associated with different types of amyloid plaques in this Alzheimer’s model. We concluded that early treatment with IDN 5706 decreases AChE-Aβ interaction and this effect might be of therapeutic interest in the treatment of AD.

Acetylcholinesterase (AChE) gene modification in transgenic animals: functional consequences of selected exon and regulatory region deletion.

Science.gov (United States)

Camp, Shelley; Zhang, Limin; Marquez, Michael; de la Torre, Brian; Long, Jeffery M; Bucht, Goran; Taylor, Palmer

2005-12-15

AChE is an alternatively spliced gene. Exons 2, 3 and 4 are invariantly spliced, and this sequence is responsible for catalytic function. The 3' alternatively spliced exons, 5 and 6, are responsible for AChE disposition in tissue [J. Massoulie, The origin of the molecular diversity and functional anchoring of cholinesterases. Neurosignals 11 (3) (2002) 130-143; Y. Li, S. Camp, P. Taylor, Tissue-specific expression and alternative mRNA processing of the mammalian acetylcholinesterase gene. J. Biol. Chem. 268 (8) (1993) 5790-5797]. The splice to exon 5 produces the GPI anchored form of AChE found in the hematopoietic system, whereas the splice to exon 6 produces a sequence that binds to the structural subunits PRiMA and ColQ, producing AChE expression in brain and muscle. A third alternative RNA species is present that is not spliced at the 3' end; the intron 3' of exon 4 is used as coding sequence and produces the read-through, unanchored form of AChE. In order to further understand the role of alternative splicing in the expression of the AChE gene, we have used homologous recombination in stem cells to produce gene specific deletions in mice. Alternatively and together exon 5 and exon 6 were deleted. A cassette containing the neomycin gene flanked by loxP sites was used to replace the exon(s) of interest. Tissue analysis of mice with exon 5 deleted and the neomycin cassette retained showed very low levels of AChE expression, far less than would have been anticipated. Only the read-through species of the enzyme was produced; clearly the inclusion of the selection cassette disrupted splicing of exon 4 to exon 6. The selection cassette was then deleted in exon 5, exon 6 and exons 5 + 6 deleted mice by breeding to Ella-cre transgenic mice. AChE expression in serum, brain and muscle has been analyzed. Another AChE gene targeted mouse strain involving a region in the first intron, found to be critical for AChE expression in muscle cells [S. Camp, L. Zhang, M. Marquez, B

SUBMARINE LANDSLIDE AND LOCALIZED TSUNAMI POTENTIALITY OF MENTAWAI BASIN, SUMATRA, INDONESIA

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Haryadi Permana

2017-07-01

Full Text Available The new bathymetry and seismic data were acquired during the PreTI-Gap marine survey (February 15 to March 6, 2008. The survey was carried out along the NE margin of Mentawai Island using multi-beam swath bathymetry equipment, and 28-channels seismic streamer and four-airgun source. The first target was the Mega Island region near the epicenter of the 2007 great earthquake. The shallow bathymetry is characterized as a flat coral platform suggesting that 200 km elongated plateau is slowly subsiding without any active faults. Further north, from South Pagai to North of Siberut Islands, the seafloor morphology changes significantly. The deep and wide canyons or valleys produce very rough seafloor morphology between 50 and 1100 m water. In general, the submarine topography shows two break slopes at different depths. Between slope breaks, the undulating, hilly and circular features dominate, possibly caused by landslides. A push-up ridge is observed that dams the sediments eroded within a steep slope northeastward side. The seismic reflection data acquired along 14 dip seismic lines at the NE flank of Mentawai Islands, from Siberut to the South of Pagai Islands. We observed a set of southwestward dipping back thrust bounding the NE margin of the Mentawai Island. Keywords: submarine landslide, tsunami, Mentawai basin, Sumatra. Data batimetri dan seismik baru telah dihasilkan selama survey kelautan PreTi-Gap (15 Februari hingga 6 Maret 2008. Survei dilaksanakan sepanjang tepian timurlaut P. Mentawai menggunakan peralatan multibeam, seismic saluran ganda 28 kanal dengan sumber energi airgun. Sasaran pertama adalah memetakan kawasan pulau dekat pusat gempa tahun 2007. Kenampakan batimetri dangkal dicirikan dengan adanya dataran terumbu karang yang secara perlahan mengalami penurunan tanpa aktifitas sesar. Lebih jauh ke Utar, dari Pagai Selatan ke utara P. Siberut, morfologi dasar laut memperlihatkan perubahan secara signifikan, dimana lembah dasar laut

Concentrations, loads and yields of organic carbon from two tropical peat swamp forest streams in Riau Province, Sumatra, Indonesia

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H.M. Yupi

2016-06-01

Full Text Available Tropical peat swamp forest (PSF stores large quantities of carbon. To estimate how much organic C is released from this type of landscape we determined organic carbon (C concentrations, loads and yields in two contrasting watercourses draining from PSF in Riau Province, Sumatra (Indonesia. Meranti Ditch (MD is an artificial watercourse whose small catchment (estimated area 4.8 km2 is in semi-intact condition, whereas Turip River (TR has a large natural catchment (estimated area 458 km2 covered with fairly intact PSF where > 75 % of the original canopy trees remain. The organic C load (Gg C yr-1 of each watercourse was calculated by combining TOC concentration with water discharge rate to give organic C yield (g C m-2 yr-1. Dissolved organic carbon (DOC was the dominant (95.0–99.8 % component of total organic carbon (TOC in the water. TOC concentration was 85–94 mg C L-1 in MD and 50–58 mg C L-1 in TR. The high concentration in MD was not surprising because this catchment had been disturbed by repeated phases of logging and a dense network of ditches was excavated ten years ago. The TOC loads were 0.23 Gg C yr-1 in MD and 14.0 Gg C yr-1 in TR. TOC yields (i.e. TOC fluxes through the fluvial system were 41.6–55.5 g C m-2 yr-1 in MD and 26.2–34.9 g C m-2 yr-1 in TR.

Ionospheric GPS TEC Anomalies and M >= 5.9 Earthquakes in Indonesia during 1993 - 2002

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Sarmoko Saroso

2008-01-01

Full Text Available Indonesia is one of the most seismically active regions in the world, containing numerous active volcanoes and subject to frequent earthquakes with epicenters distributed along the same regions as volcanoes. In this paper, a case study is carried out to investigate pre-earthquake ionospheric anomalies in total electron content (TEC during the Sulawesi earthquakes of 1993 - 2002, and the Sumatra-Andaman earthquake of 26 December 2004, the largest earthquake in the world since 1964. It is found that the ionospheric TECs remarkably decrease within 2 - 7 days before the earthquakes, and for the very powerful Sumatra-Andaman earthquake, the anomalies extend up to about 1600 km from the epicenter.

Assessing ecosystem carbon stocks of Indonesia's threatened wetland forests

Science.gov (United States)

Warren, M.; Kauffman, B.; Murdiyarso, D.; Kurnianto, S.

2011-12-01

Over millennia, atmospheric carbon dioxide has been sequestered and stored in Indonesia's tropical wetland forests. Waterlogged conditions impede decomposition, allowing the formation of deep organic soils. These globally significant C pools are highly vulnerable to deforestation, degradation and climate change which can potentially switch their function as C sinks to long term sources of greenhouse gas (GHG) emissions. Also at risk are critical ecosystem services which sustain millions of people and the conservation of unique biological communities. The multiple benefits derived from wetland forest conservation makes them attractive for international C offset programs such as the proposed Reduced Emissions from Deforestation and Degradation (REDD+) mechanism. Yet, ecosystem C pools and fluxes in wetland forests remain poorly quantified. Significant knowledge gaps exist regarding how land use changes impact C dynamics in tropical wetlands, and very few studies have simultaneously assessed above- and belowground ecosystem C pools in Indonesia's freshwater peat swamps and mangroves. In addition, most of what is known about Indonesia's tropical wetland forests is derived from few geographic locations where long-standing research has focused, despite their broad spatial distribution. Here we present results from an extensive survey of ecosystem C stocks across several Indonesian wetland forests. Ecosystem C stocks were measured in freshwater peat swamp forests in West Papua, Central Kalimantan, West Kalimantan, and Sumatra. Carbon storage was also measured for mangrove forests in W. Papua, W. Kalimantan, and Sumatra. One overarching goal of this research is to support the development of REDD+ for tropical wetlands by informing technical issues related to carbon measuring, monitoring, and verification (MRV) and providing baseline data about the variation of ecosystem C storage across and within several Indonesian wetland forests.

SIMULASI GELOMBANG EKSTRIM AKIBAT SWELL DI INDONESIA MENGGUNAKAN MODEL WAVEWATCH-III

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Muhammad Najib Habibie

2015-01-01

menyebabkan superposisi antara swell dan pasang surut dan menambah ketinggian swell.   Indonesia lies between Hindia and Pacific ocean, it caused hight risk in extreme wave from both of them. One of extreme wave events occured on May 17-19, 2007. This event damaged many infrastructure over western coast of Sumatra until southern Nusa Tenggara. The purpose of this research is to investigate WAVEWATCH-III performance to simulate the extreme wave in Indonesia waters. 10 m of wind from Global Forcasting System (GFS and bathimetry from US Geological Survey (USGS used as input model to simulate the wind wave on global and regional domain during May 1-31, 2007, and than verified by ERA-Interim data. The simulation shown that these extreme wave event triggered by tropical cyclone in Cape of Hope, southern of Africa. The cyclone caused persistent wind more than 22 m/s speed and leads to Indonesia waters. This condition took place during May 4-10, 2007 and generated extreme wave more than 3 meter over the western coast of Sumatra, the southern coast of Java to Flores. The extreme wave considered as swell. The persistent wind generated wind sea and grown to swell leads to Indonesia waters across Hindian Ocean. The model has been verified by ERA-Interim reanalysis data, it has a good correlation (0,92-0,97 and MAE between 0,13-0,45 m. But the model data higher than ERA-Interim because the resolution of the model higher too. Based on the simulation, more than 20 seconds wave period recorded in coastal areas. This hundreds meters of wavelength having setup due to bottom friction, so these wave are destructive and dangerous. These event resembling with spring tide, so superposition about swell and tide caused wave setup.

Four new species of Arenga (Palmae from Indonesia

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Johanis Palar Mogea

2003-12-01

Full Text Available MOGEA, JOHANIS P. 2004. Four new species of Arenga (Palmae from Indonesia. Reinwardtia 12 (2: 181 – 189. ― Arenga distincta from Borneo and A. longipes, A. plicata, and A. talamauensis from Sumatra are described and illustrated for the first time. The descriptions are followed by  information regarding the habitat and  geographical distribution, and notes on morphological similarities with other, presumably related species.  Leaves of A. longipes and A.  talamauensis are paripinnate while the other two species are imparipinnate.  

Hospitalitermes krishnai, a new nasute termite (Nasutitermitinae, Termitidae, Isoptera, from southern Sumatra, Indonesia

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Syaukani Syaukani

2011-11-01

Full Text Available A new species of nasute termite, Hospitalitermes krishnai sp. n., is described from soldiers and workers discovered in Lampung Province, Sumatra. This species can be distinguished from other related Hospitalitermes species from Southeast Asia by the anterior part of head capsule that is much smaller than the posterior part, head capsule that is moderately constricted behind the antennal sockets, and relatively deep depression between the head and nasus and, finally, the short and robust nasus measuring less than half as long as head capsule. Moreover, in profile the nasus is slightly up-curved but slightly decurved at the apical tip. We name this new species after Professor Kumar Krishna in recognition of his life-long contributions to termite taxonomy, systematics and biology.

Social innovation to promote sustainability and independence of small-scale palm oil farmers in the Province of Jambi, Indonesia

OpenAIRE

Firman, Anita Nathalia

2017-01-01

The aim of this thesis was to investigate the situation of the independent small-scale palm oil farmers in the Province of Jambi, Indonesia regarding the practices of palm oil production that cause deforestation in Sumatra. The goal of this thesis was to provide sustainable opportunities for the independent small-scale farmers in Jambi through social innovation. The field research took place at the village of Mekar Jaya and Sungai Rotan Village in the Provinces of Jambi, Indonesia. In the fra...

Assessing the reactivation efficacy of hydroxylamine anion towards VX-inhibited AChE: a computational study.

Science.gov (United States)

Khan, Md Abdul Shafeeuulla; Ganguly, Bishwajit

2012-05-01

Oximate anions are used as potential reactivating agents for OP-inhibited AChE because of they possess enhanced nucleophilic reactivity due to the α-effect. We have demonstrated the process of reactivating the VX-AChE adduct with formoximate and hydroxylamine anions by applying the DFT approach at the B3LYP/6-311 G(d,p) level of theory. The calculated results suggest that the hydroxylamine anion is more efficient than the formoximate anion at reactivating VX-inhibited AChE. The reaction of formoximate anion and the VX-AChE adduct is a three-step process, while the reaction of hydroxylamine anion with the VX-AChE adduct seems to be a two-step process. The rate-determining step in the process is the initial attack on the VX of the VX-AChE adduct by the nucleophile. The subsequent steps are exergonic in nature. The potential energy surface (PES) for the reaction of the VX-AChE adduct with hydroxylamine anion reveals that the reactivation process is facilitated by the lower free energy of activation (by a factor of 1.7 kcal mol(-1)) than that of the formoximate anion at the B3LYP/6-311 G(d,p) level of theory. The higher free energy of activation for the reverse reactivation reaction between hydroxylamine anion and the VX-serine adduct further suggests that the hydroxylamine anion is a very good antidote agent for the reactivation process. The activation barriers calculated in solvent using the polarizable continuum model (PCM) for the reactivation of the VX-AChE adduct with hydroxylamine anion were also found to be low. The calculated results suggest that V-series compounds can be more toxic than G-series compounds, which is in accord with earlier experimental observations.

The role of the state coal mining enterprise in Indonesia

International Nuclear Information System (INIS)

Mangunwidjaja, I.A.

1991-01-01

This paper reports that PT Tambang Batubara Bukit Asam is now becoming one of the 3 State Mining Enterprises in Indonesia which is dealing specifically with coal minings and their developments, while the other 2 are PT Tambang Timah for tin and PT Aneka Tambang for miscellaneous minerals. However, there are actually 3 other more State Enterprises under the umbrella of the Department of Mines and Energy, namely PERTAMINA which is dealing with oil and natural gas exploitation, PLN which is the State Electricity Corporation and the State Gas Corporation. The process of merging into one State Coal Mining Enterprise was only happening on October 30, 1990 by the issuance of the Government Regulation Number 56, 1991 whereby the then called Perum Tambang Batubara was merged into PT Tambang Batubara Bukit Asam, which was then operating only in Tanjung Enim, South Sumatra. The new scope of operation and management of the PT Tambang Batubara Bukit Asam is now including not only the management of coal mines at Tanjung Enim South Sumatra, but also the coal mines at Ombilin, West Sumatra and the supervision of all contract of works in coal which up to now amount to 11, mostly spread in East Kalimantan, South Kalimantan and one in West Sumatra. The amount of coal produced by PT Tambang Batubara Bukit Asam in 1990 was 4,854 million tons, while the coal production from all contract of works was 4,059 million tons for the same year

ANALISA PERUBAHAN IONOSFER AKIBAT GEMPA MENTAWAI TAHUN 2010 (Studi Kasus : Kepulauan Mentawai, Sumatra Barat

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Leni Septiningrum

2017-01-01

Full Text Available Gempa merupakan fenomena alam akibat aktifitas tektonik yang sering terjadi di Indonesia. Sepanjang pulau Sumatra merupakan pertumbukan antara lempeng Indo-Australia dan lempeng Eurasia menjadikan Sumatra sebagai daerah paling aktif dengan aktifitas tektoniknya. Pada tahun 2010 tercatat tiga gempa besar yang terjadi, yaitu gempa berkekuatan 6,8 SR pada 5 Maret, disusul 6,5 SR pada 5 Mei dan terakhir 7,8 SR pada 25 Oktober 2010. Post-earthquake anomali merupakan fluktuasi TEC yang terjadi sesaat setelah terjadinya gempa, fenomena ini terjadi 3 menit hingga 1 jam setelah gempa terjadi. Post-earthquake anomali dapat digunakan sebagai early warning sebelum tsunami datang. Pengamatan TEC (Total Electron Content dilakukan dengan menggunakan GPS. Satelit GPS akan secara kontinyu memancarkan sinyal gelombang double frequency pada L band. Pada saat terjadi gempa, sinyal yang dipancarkan oleh satelit GPS akan mengalami delay ketika melewati lapisan ionosfer kira-kira 300 km dari permukaan bumi. Variasi ionosfer diamati pada saat terjadi time-delay ini, sehingga didapat nilai TEC dimana I TECU sama dengan 1016 elektron/m2. Nilai tersebut yang akan menggambarkan besaran gangguan akibat adanya gempa. Pada gempa Mentawai 2010 dengan menggunakan stasiun pengamat GPS pada ketiga kejadian gempa tidak menunjukkan adanya gangguan pada ionosfer, hanya terjadi fluktuasi pada beberapa stasiun pengamat.

Variasi Genetik Trenggiling Sitaan di Sumatra, Jawa, dan Kalimantan Berdasarkan Control Region DNA Mitokndria (GENETIC VARIATION ON CONFISCATED PANGOLIN OF SUMATRA, JAWA, AND KALIMANTAN BASED ON CONTROL REGION MITOCHONDRIAL DNA

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Wirdateti Wirdateti

2017-06-01

Full Text Available High levels of illegal trading on Java pangolin (Manis javanica, Desmarest. 1822 for the basic ingredient of Traditional Chinese Medicine have caused sharp decline in its wild population. The purposes of this study were to assess the level of quality and genetic diversity, and to identify the origin of the confiscated individuals by molecular analysis. The original species used as a control were obtained from known areas in Java, Kalimantan, and Sumatera. Molecular analysis was carried out using non-coding region control region (D-loop of mitochondrial DNA (mtDNA. The results of phylogenic tree analysis showed that 44 confiscated pangolins were from Kalimantan (24 individuals, from Sumatra (seven individuals, and from Java (13 individuals. As many as 19 haplotypes were found on the basis of their base substitutions consisting of nine from Kalimantan, seven from Java and three from Sumatra. Average genetic distance (d between those from Kalimantan-Java was d = 0.0121 ± 0.0031; those from Borneo-Sumatra was d =0.0123 ± 0.0038 and those from Sumatra-Java was d = 0.0075 ± 0.038, respectively. Overall genetic distance between populations was d = 0.0148 ± 0.0035, with the nucleotide diversity (ð of 0.0146. These results indicate that over 50% of pangolins seized came from Kaimantan, and Kalimantan populations show a separate group with Java and Sumatra with boostrap 98%. ABSTRAK Tingginya tingkat perburuan trenggiling (Manis javanica; Desmarest 1822 Indonesia untuk diperdagangkan secara illegal sebagai bahan dasar obat terutama di China, menyebabkan terjadinya penurunan populasi di alam. Tujuan penelitian ini adalah untuk melihat tingkat kualitas dan keragaman genetik trenggiling serta mengetahui asal usul satwa sitaan berdasarkan analisis molekuler. Sebagai kontrol asal usul trenggiling sitaan digunakan sampel alam berdasarkan sebaran populasi yang diketahui pasti yang berasal dari Jawa, Kalimantan, dan Sumatera. Analisis molekuler menggunakan

Plasmodium ovale in Indonesia.

Science.gov (United States)

Baird, J K; Purnomo; Masbar, S

1990-12-01

We report 34 infections by Plasmodium ovale found among 15,806 blood film examinations taken between 1973 and 1989 from several sites in Indonesia. Twenty five of the P. ovale infections occurred in a single sample of 514 people living in Owi, Irian Jaya. We detected five additional infections at 3 other sites in Irian Jaya. Other infections by P. ovale occurred at two sites in West Flores. Another infection has already been reported from East Timor. Despite relatively frequent sampling of populations on Sumatra, Kalimantan, Java and Sulawesi, P. ovale has not been found on those islands. It appears that this parasite occurs only on the easternmost islands of the Indonesian archipelago where it is nonetheless a rare finding.

Toxicological and biochemical characterizations of AChE in phosalone-susceptible and resistant populations of the common pistachio psyllid, Agonoscena pistaciae

Science.gov (United States)

Alizadeh, Ali; Talebi-Jahromi, Khalil; Hosseininaveh, Vahid; Ghadamyari, Mohammad

2014-01-01

Abstract The toxicological and biochemical characteristics of acetylcholinesterases (AChE) in nine populations of the common pistachio psyllid, Agonoscena pistaciae Burckhardt and Lauterer (Hemiptera: Psyllidae), were investigated in Kerman Province, Iran. Nine A. pistaciae populations were collected from pistachio orchards, Pistacia vera L. (Sapindales: Anacardiaceae), located in Rafsanjan, Anar, Bam, Kerman, Shahrbabak, Herat, Sirjan, Pariz, and Paghaleh regions of Kerman province. The previous bioassay results showed these populations were susceptible or resistant to phosalone, and the Rafsanjan population was most resistant, with a resistance ratio of 11.3. The specific activity of AChE in the Rafsanjan population was significantly higher than in the susceptible population (Bam). The affinity ( KM ) and hydrolyzing efficiency ( Vmax ) of AChE on acetylthiocholine iodide, butyrylthiocholine iodide, and propionylthiocholine odide as artificial substrates were clearly lower in the Bam population than that in the Rafsanjan population. These results indicated that the AChE of the Rafsanjan population had lower affinity to these substrates than that of the susceptible population. The higher Vmax value in the Rafsanjan population compared to the susceptible population suggests a possible over expression of AChE in the Rafsanjan population. The in vitro inhibitory effect of several organophosphates and carbamates on AChE of the Rafsanjan and Bam populations was determined. Based on I50, the results showed that the ratios of AChE insensitivity of the resistant to susceptible populations were 23 and 21.7-fold to monocrotophos and phosphamidon, respectively. Whereas, the insensitivity ratios for Rafsanjan population were 0.86, 0.8, 0.78, 0.46, and 0.43 for carbaryl, eserine, propoxur, m-tolyl methyl carbamate, and carbofuran, respectively, suggesting negatively correlated sensitivity to organophosphate-insensitive AChE. Therefore, AChE from the Rafsanjan population showed

Monitoring the Sumatra volcanic arc with InSAR

Science.gov (United States)

Chaussard, E.; Hong, S.; Amelung, F.

2009-12-01

The Sumatra volcanic arc is the result of the subduction of the Indo-Australian plate under the Sunda plate. The arc consists of 35 known volcanic centers, subaerials on the west coast of the Sumatra and Andaman Islands and submarines between these islands. Six active centers are known in the Sumatra volcanic arc. Surface deformation in volcanic areas usually indicates movement of magma or hydrothermal fluids at depth. Here we present a satellite-based Interferometric synthetic aperture radar (InSAR) survey of the Sumatra volcanic arc using ALOS data. Spanning the years 2007 to beginning of 2009, our survey reveals the background level of activity of the 35 volcanoes. We processed data from 40 tracks (24 in descending orbit and 16 in ascending orbit) to cover the whole Sumatra arc. In the first results five of these six known active centers show no sign of activity: Dempo, Kaba, Marapi, Talang and Peuet. The remaining active volcano, Mount Kerinci, has an ambiguous signal. We used pair-wise logic and InSAR time series of the available ALOS data to determine if the observed InSAR signal is caused by ground deformation or by atmospheric delays.

Late Quaternary eruption of the Ranau Caldera and new geological slip rates of the Sumatran Fault Zone in Southern Sumatra, Indonesia

Science.gov (United States)

Natawidjaja, Danny Hilman; Bradley, Kyle; Daryono, Mudrik R.; Aribowo, Sonny; Herrin, Jason

2017-12-01

Over the last decade, studies of natural hazards in Sumatra have focused primarily on great earthquakes and associated tsunamis produced by rupture of the Sunda megathrust. However, the Sumatran Fault and the active volcanic arc present proximal hazards to populations on mainland Sumatra. At present, there is little reliable information on the maximum magnitudes and recurrence intervals of Sumatran Fault earthquakes, or the frequency of paroxysmal caldera-forming (VEI 7-8) eruptions. Here, we present new radiocarbon dates of paleosols buried under the voluminous Ranau Tuff that constrain the large caldera-forming eruption to around 33,830-33,450 calender year BP (95% probability). We use the lateral displacement of river channels incised into the Ranau Tuff to constrain the long-term slip rate of two segments of the Sumatran Fault. South of Ranau Lake, the Kumering segment preserves isochronous right-lateral channel offsets of approximately 350 ± 50 m, yielding a minimum slip rate of 10.4 ± 1.5 mm/year for the primary active fault trace. South of Suoh pull-apart depression, the West Semangko segment offsets the Semangko River by 230 ± 60 m, yielding an inferred slip rate of 6.8 ± 1.8 mm/year. Compared with previous studies, these results indicate more recent high-volume volcanism in South Sumatra and increased seismic potency of the southernmost segments of the Sumatran Fault Zone.

Capacity Development and Strengthening for Energy Policy formulation and implementation of Sustainable Energy Projects in Indonesia CASINDO. Deliverable No. 17. Development of Education Programs at Indonesian Universities

Energy Technology Data Exchange (ETDEWEB)

Wijnker, M. [Eindhoven University of Technology TUE, Eindhoven (Netherlands)

2011-08-15

The overall objective of the CASINDO programme is to establish a self-sustaining and self-developing structure at both the national and regional level to build and strengthen human capacity to enable the provinces of North Sumatra, Yogyakarta, Central Java, West Nusa Tenggara and Papua to formulate sound policies for renewable energy and energy efficiency and to develop and implement sustainable energy projects. All five Indonesian partner universities managed to develop and implement an education program within the timeline of the CASINDO project. UMY (Muhammadiyah University of Yogyakarta, Indonesia), UNRAM (University of Mataram, Mataram, Indonesia) and UNCEN (Cenderawasih University, Jayapura, Papua, Indonesia) have chosen to develop a certificate program. UNDIP (Diponegoro University in Semarang, Java, Indonesia) and USU (University of Sumatra Utara, Medan, Indonesia) have both developed a master program in sustainable energy. UNDIP has already discussed the proposal of their master program with the Ministry of Education and will have to make some improvements. USU will first start the program as a specialisation within the Mechanical Engineering department and in some time continues to make it an independent master program. At all universities both contact persons and lecturers have put a lot of effort in developing the programs and succeeded. Additionally, through CASINDO a network of lecturers between the universities has developed, which will ease future cooperation, after the CASINDO project will have finished.

Tropical Indo-Pacific hydroclimate response to North Atlantic forcing during the last deglaciation as recorded by a speleothem from Sumatra, Indonesia

Science.gov (United States)

Wurtzel, Jennifer B.; Abram, Nerilie J.; Lewis, Sophie C.; Bajo, Petra; Hellstrom, John C.; Troitzsch, Ulrike; Heslop, David

2018-06-01

Abrupt changes in Atlantic Meridional Overturning Circulation are known to have affected the strength of the Indian and Asian Monsoons during glacial and deglacial climate states. However, there is still much uncertainty around the hydroclimate response of the Indo-Pacific Warm Pool (IPWP) region to abrupt climate changes in the North Atlantic. Many studies suggest a mean southward shift in the intertropical convergence zone (ITCZ) in the IPWP region during phases of reduced Atlantic meridional overturning, however, existing proxies have seasonal biases and conflicting responses, making it difficult to determine the true extent of North Atlantic forcing in this climatically important region. Here we present a precisely-dated, high-resolution record of eastern Indian Ocean hydroclimate variability spanning the last 16 ky (thousand years) from δ18O measurements in an aragonite-calcite speleothem from central Sumatra. This represents the western-most speleothem record from the IPWP region. Precipitation arrives year-round at this site, with the majority sourced from the local tropical eastern Indian Ocean and two additional long-range seasonal sources associated with the boreal and austral summer monsoons. The Sumatran speleothem demonstrates a clear deglacial structure that includes 18O enrichment during the Younger Dryas and 18O depletion during the Bølling-Allerød, similar to the pattern seen in speleothems of the Asian and Indian monsoon realms. The speleothem δ18O changes at this site are best explained by changes in rainfall amount and changes in the contributions from different moisture pathways. Reduced rainfall in Sumatra during the Younger Dryas is most likely driven by reductions in moisture transport along the northern or southern monsoon transport pathways to Sumatra. Considered with other regional proxies, the record from Sumatra suggests the response of the IPWP to North Atlantic freshwater forcing is not solely driven by southward shifts of the

Novel bis-(−)-nor-meptazinol derivatives act as dual binding site AChE inhibitors with metal-complexing property

Energy Technology Data Exchange (ETDEWEB)

Zheng, Wei [Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 200032 (China); NPFPC Key Laboratory of Contraceptives and Devices, Shanghai Institute of Planned Parenthood Research, 2140 Xietu Road, Shanghai 200032 (China); Li, Juan [Department of Pharmacology, Institute of Medical Sciences, Shanghai Jiaotong University School of Medicine, 280 South Chongqing Road, Shanghai 200025 (China); Qiu, Zhuibai [Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 200032 (China); Xia, Zheng [Department of Pharmacology, Institute of Medical Sciences, Shanghai Jiaotong University School of Medicine, 280 South Chongqing Road, Shanghai 200025 (China); Li, Wei [Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 200032 (China); Yu, Lining; Chen, Hailin; Chen, Jianxing [NPFPC Key Laboratory of Contraceptives and Devices, Shanghai Institute of Planned Parenthood Research, 2140 Xietu Road, Shanghai 200032 (China); Chen, Yan; Hu, Zhuqin; Zhou, Wei; Shao, Biyun; Cui, Yongyao [Department of Pharmacology, Institute of Medical Sciences, Shanghai Jiaotong University School of Medicine, 280 South Chongqing Road, Shanghai 200025 (China); Xie, Qiong, E-mail: xiejoanxq@gmail.com [Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 200032 (China); Chen, Hongzhuan, E-mail: yaoli@shsmu.edu.cn [Department of Pharmacology, Institute of Medical Sciences, Shanghai Jiaotong University School of Medicine, 280 South Chongqing Road, Shanghai 200025 (China)

2012-10-01

The strategy of dual binding site acetylcholinesterase (AChE) inhibition along with metal chelation may represent a promising direction for multi-targeted interventions in the pathophysiological processes of Alzheimer's disease (AD). In the present study, two derivatives (ZLA and ZLB) of a potent dual binding site AChE inhibitor bis-(−)-nor-meptazinol (bis-MEP) were designed and synthesized by introducing metal chelating pharmacophores into the middle chain of bis-MEP. They could inhibit human AChE activity with IC{sub 50} values of 9.63 μM (for ZLA) and 8.64 μM (for ZLB), and prevent AChE-induced amyloid-β (Aβ) aggregation with IC{sub 50} values of 49.1 μM (for ZLA) and 55.3 μM (for ZLB). In parallel, molecular docking analysis showed that they are capable of interacting with both the catalytic and peripheral anionic sites of AChE. Furthermore, they exhibited abilities to complex metal ions such as Cu(II) and Zn(II), and inhibit Aβ aggregation triggered by these metals. Collectively, these results suggest that ZLA and ZLB may act as dual binding site AChEIs with metal-chelating potency, and may be potential leads of value for further study on disease-modifying treatment of AD. -- Highlights: ► Two novel bis-(−)-nor-meptazinol derivatives are designed and synthesized. ► ZLA and ZLB may act as dual binding site AChEIs with metal-chelating potency. ► They are potential leads for disease-modifying treatment of Alzheimer's disease.

Novel bis-(−)-nor-meptazinol derivatives act as dual binding site AChE inhibitors with metal-complexing property

International Nuclear Information System (INIS)

Zheng, Wei; Li, Juan; Qiu, Zhuibai; Xia, Zheng; Li, Wei; Yu, Lining; Chen, Hailin; Chen, Jianxing; Chen, Yan; Hu, Zhuqin; Zhou, Wei; Shao, Biyun; Cui, Yongyao; Xie, Qiong; Chen, Hongzhuan

2012-01-01

The strategy of dual binding site acetylcholinesterase (AChE) inhibition along with metal chelation may represent a promising direction for multi-targeted interventions in the pathophysiological processes of Alzheimer's disease (AD). In the present study, two derivatives (ZLA and ZLB) of a potent dual binding site AChE inhibitor bis-(−)-nor-meptazinol (bis-MEP) were designed and synthesized by introducing metal chelating pharmacophores into the middle chain of bis-MEP. They could inhibit human AChE activity with IC 50 values of 9.63 μM (for ZLA) and 8.64 μM (for ZLB), and prevent AChE-induced amyloid-β (Aβ) aggregation with IC 50 values of 49.1 μM (for ZLA) and 55.3 μM (for ZLB). In parallel, molecular docking analysis showed that they are capable of interacting with both the catalytic and peripheral anionic sites of AChE. Furthermore, they exhibited abilities to complex metal ions such as Cu(II) and Zn(II), and inhibit Aβ aggregation triggered by these metals. Collectively, these results suggest that ZLA and ZLB may act as dual binding site AChEIs with metal-chelating potency, and may be potential leads of value for further study on disease-modifying treatment of AD. -- Highlights: ► Two novel bis-(−)-nor-meptazinol derivatives are designed and synthesized. ► ZLA and ZLB may act as dual binding site AChEIs with metal-chelating potency. ► They are potential leads for disease-modifying treatment of Alzheimer's disease.

Peramalan Jumlah Produksi Kakao Di Sumatera Utara Dan Konsumsi Kakao Di Indonesia Dengan Pemulusan Eksponensial Ganda Metode Linier Satu Parameter Dari Brown

OpenAIRE

Maranata, Lauda

2015-01-01

Forecasting is a way to estimate a condition that could happen in the future, so that a program can be implemented appropriately. This research includes the forecasting of cocoa production in North Sumatra and cocoa consumption in Indonesia in purpose to see how the production meet the needs of cocoa in Indonesia. Double Exponential Smoothing One Parameter by Brown is a method which is used in this research. The results show that the production and consumption of cocoa keep increasing. The fo...

Transition of microbiological and sedimentological features associated with the geochemical gradient in a travertine mound in northern Sumatra, Indonesia

Science.gov (United States)

Sugihara, Chiya; Yanagawa, Katsunori; Okumura, Tomoyo; Takashima, Chizuru; Harijoko, Agung; Kano, Akihiro

2016-08-01

Modern travertines, carbonate deposits in Ca-rich hydrothermal water with high pCO2, often display a changing environment along the water path, with corresponding variability in the microbial communities. We investigated a travertine-bearing hot spring at the Blue Pool in northern Sumatra, Indonesia. The thermal water of 62 °C with high H2S (200 μM) and pCO2 ( 1 atm) developed a travertine mound 70 m wide. The concentrations of the gas components H2S and CO2, decrease immediately after the water is discharged, while the dissolved oxygen, pH, and aragonite saturation increase in the downstream direction. Responding to the geochemical gradient in the water, the surface biofilms change color from white to pink, light-green, dark-green, and brown as the water flows from the vent; this corresponds to microbial communities characterized by chemolithoautotrophs (Halothiobacillaceae), purple sulfur bacteria (Chromatiaceae), Anaerolineaceae, and co-occurrence of green non-sulfur bacteria (Chloroflexales)-Cyanobacteria, and green sulfur bacteria (Chlorobiales), respectively. In an environment with a certain level of H2S (> 1 μM), sulfur digestion and anoxygenic photosynthesis can be more profitable than oxygenic photosynthesis by Cyanobacteria. The precipitated carbonate mineral consists of aragonite and calcite, with the proportion of aragonite increasing downstream due to the larger Mg2 +/Ca2 + ratio in the water or the development of thicker biofilm. Where the biofilm is well developed, the aragonite travertines often exhibit laminated structures that were likely associated with the daily metabolism of these bacteria. The microbiological and sedimentological features at the Blue Pool may be the modern analogs of geomicrobiological products in the early Earth. Biofilm of anoxygenic photosynthetic bacteria had the potential to form ancient stromatolites that existed before the appearance of cyanobacteria.

Development of the first coal seam gas exploration program in Indonesia: Reservoir properties of the Muaraenim Formation, south Sumatra

Energy Technology Data Exchange (ETDEWEB)

Sosrowidjojo, I.B. [R and D Centre for Oil and Gas Technology, LEMIGAS, Jakarta (Indonesia); Saghafi, A. [CSIRO Energy Technology, P O Box 330, Newcastle, NSW, 2300 (Australia)

2009-09-01

The Late Miocene Muaraenim Formation in southern Sumatra contains thick coal sequences, mostly of low rank ranging from lignite to sub-bituminous, and it is believed that these thick low rank coals are the most prospective for the production of coal seam gas (CSG), otherwise known as coalbed methane (CBM), in Indonesia. As part of a major CSG exploration project, gas exploration drilling operations are being undertaken in Rambutan Gasfields in the Muaraenim Formation to characterize the CSG potential of the coals. The first stage of the project, which is described here, was designed to examine the gas reservoir properties with a focus on coal gas storage capacity and compositional properties. Some five CSG exploration boreholes were drilled in the Rambutan Gasfield, south of Palembang. The exploration boreholes were drilled to depths of {proportional_to} 1000 m into the Muaraenim Formation. Five major coal seams were intersected by these holes between the depths of 450 and 1000 m. The petrography of coal samples collected from these seams showed that they are vitrinite rich, with vitrinite contents of more than 75% (on a mineral and moisture free basis). Gas contents of up to 5.8 m{sup 3}/t were measured for the coal samples. The gas desorbed from coal samples contain mainly methane (CH{sub 4}) ranging from 80 to 93% and carbon dioxide (CO{sub 2}) ranging from 6 to 19%. The composition of the gas released into the production borehole/well is, however, much richer in CH{sub 4} with about 94 to 98% CH{sub 4} and less than 5% CO{sub 2}. The initial results of drilling and reservoir characterization studies indicate suitable gas recovery parameters for three of the five coal seams with a total thickness of more than 30 m. (author)

Seismic Hazard characterization study using an earthquake source with Probabilistic Seismic Hazard Analysis (PSHA) method in the Northern of Sumatra

International Nuclear Information System (INIS)

Yahya, A.; Palupi, M. I. R.; Suharsono

2016-01-01

Sumatra region is one of the earthquake-prone areas in Indonesia because it is lie on an active tectonic zone. In 2004 there is earthquake with a moment magnitude of 9.2 located on the coast with the distance 160 km in the west of Nanggroe Aceh Darussalam and triggering a tsunami. These events take a lot of casualties and material losses, especially in the Province of Nanggroe Aceh Darussalam and North Sumatra. To minimize the impact of the earthquake disaster, a fundamental assessment of the earthquake hazard in the region is needed. Stages of research include the study of literature, collection and processing of seismic data, seismic source characterization and analysis of earthquake hazard by probabilistic methods (PSHA) used earthquake catalog from 1907 through 2014. The earthquake hazard represented by the value of Peak Ground Acceleration (PGA) and Spectral Acceleration (SA) in the period of 0.2 and 1 second on bedrock that is presented in the form of a map with a return period of 2475 years and the earthquake hazard curves for the city of Medan and Banda Aceh. (paper)

Implication of Land-Use and Land-Cover Change into Carbon Dioxide Emissions in Karang Gading and Langkat Timur Wildlife Reserve, North Sumatra, Indonesia

Directory of Open Access Journals (Sweden)

Mohammad Basyuni

2015-06-01

Full Text Available Mangrove forest in the context of climate change is important sector to be included in the inventory of greenhouse gas (GHG emissions. The present study describes land-use and land-cover change during 2006–2012 of a mangrove forest conservation area, Karang Gading and Langkat Timur Laut Wildlife Reserve (KGLTLWR in North Sumatra, Indonesia and their implications to carbon dioxide emissions. A land-use change matrix showed that the decrease of mangrove forest due to increases of other land-use such as aquaculture (50.00% and oil palm plantation (28.83%. Furthermore, the net cumulative of carbon emissions in KGLTLWR for 2006 was 3804.70 t CO2-eq year-1, whereas predicting future emissions in 2030 was 11,318.74 t CO2-eq year-1 or an increase of 33.61% for 12 years. Source of historical emissions mainly from changes of secondary mangrove forests into aquaculture and oil palm plantation were 3223.9 t CO2-eq year-1 (84.73% and 959.00 t CO2-eq year-1 (25.21%, respectively, indicating that the KGLTLWR is still a GHG emitter. Mitigation scenario with no conversion in secondary mangrove forest reduced 16.21% and 25.8% carbon emissions in 2024 and 2030, respectively. This study suggested that aquaculture and oil palm plantation are drivers of deforestation as well as the largest of GHG emission source in this area. Keywords: carbon emission, climate change, deforestation, forest degradation, mangrove conservation

Vertical deformation at western part of Sumatra

Energy Technology Data Exchange (ETDEWEB)

Febriyani, Caroline, E-mail: caroline.fanuel@students.itb.ac.id; Prijatna, Kosasih, E-mail: prijatna@gd.itb.ac.id; Meilano, Irwan, E-mail: irwan.meilano@gd.itb.ac.id

2015-04-24

This research tries to make advancement in GPS signal processing to estimate the interseismic vertical deformation field at western part of Sumatra Island. The data derived by Continuous Global Positioning System (CGPS) from Badan Informasi Geospasial (BIG) between 2010 and 2012. GPS Analyze at Massachusetts Institute of Technology (GAMIT) software and Global Kalman Filter (GLOBK) software are used to process the GPS signal to estimate the vertical velocities of the CGPS station. In order to minimize noise due to atmospheric delay, Vienna Mapping Function 1 (VMF1) is used as atmospheric parameter model and include daily IONEX file provided by the Center for Orbit Determination in Europe (CODE) as well. It improves GAMIT daily position accuracy up to 0.8 mm. In a second step of processing, the GLOBK is used in order to estimate site positions and velocities in the ITRF08 reference frame. The result shows that the uncertainties of estimated displacement velocity at all CGPS stations are smaller than 1.5 mm/yr. The subsided deformation patterns are seen at the northern and southern part of west Sumatra. The vertical deformation at northern part of west Sumatra indicates postseismic phase associated with the 2010 and 2012 Northern Sumatra earthquakes and also the long-term postseismic associated with the 2004 and 2005 Northern Sumatra earthquakes. The uplifted deformation patterns are seen from Bukit Tinggi to Seblat which indicate a long-term interseismic phase after the 2007 Bengkulu earthquake and 2010 Mentawai earthquake. GANO station shows a subsidence at rate 12.25 mm/yr, indicating the overriding Indo-Australia Plate which is dragged down by the subducting Southeast Asian Plate.

Evaluation of the Toxicity, AChE Activity and DNA Damage Caused by Imidacloprid on Earthworms, Eisenia fetida.

Science.gov (United States)

Wang, Kai; Qi, Suzhen; Mu, Xiyan; Chai, Tingting; Yang, Yang; Wang, Dandan; Li, Dongzhi; Che, Wunan; Wang, Chengju

2015-10-01

Imidacloprid is a well-known pesticide and it is timely to evaluate its toxicity to earthworms (Eisenia fetida). In the present study, the effect of imidacloprid on reproduction, growth, acetylcholinesterase (AChE) and DNA damage in earthworms was assessed using an artificial soil medium. The median lethal concentration (LC50) and the median number of hatched cocoons (EC50) of imidacloprid to earthworms was 3.05 and 0.92 mg/kg respectively, the lowest observed effect concentration of imidacloprid about hatchability, growth, AChE activity and DNA damage was 0.02, 0.5, 0.1 and 0.5 mg/kg, respectively.

Seasonal forecasting of fire over Kalimantan, Indonesia

Science.gov (United States)

Spessa, A. C.; Field, R. D.; Pappenberger, F.; Langner, A.; Englhart, S.; Weber, U.; Stockdale, T.; Siegert, F.; Kaiser, J. W.; Moore, J.

2015-03-01

Large-scale fires occur frequently across Indonesia, particularly in the southern region of Kalimantan and eastern Sumatra. They have considerable impacts on carbon emissions, haze production, biodiversity, health, and economic activities. In this study, we demonstrate that severe fire and haze events in Indonesia can generally be predicted months in advance using predictions of seasonal rainfall from the ECMWF System 4 coupled ocean-atmosphere model. Based on analyses of long, up-to-date series observations on burnt area, rainfall, and tree cover, we demonstrate that fire activity is negatively correlated with rainfall and is positively associated with deforestation in Indonesia. There is a contrast between the southern region of Kalimantan (high fire activity, high tree cover loss, and strong non-linear correlation between observed rainfall and fire) and the central region of Kalimantan (low fire activity, low tree cover loss, and weak, non-linear correlation between observed rainfall and fire). The ECMWF seasonal forecast provides skilled forecasts of burnt and fire-affected area with several months lead time explaining at least 70% of the variance between rainfall and burnt and fire-affected area. Results are strongly influenced by El Niño years which show a consistent positive bias. Overall, our findings point to a high potential for using a more physical-based method for predicting fires with several months lead time in the tropics rather than one based on indexes only. We argue that seasonal precipitation forecasts should be central to Indonesia's evolving fire management policy.

THE ROLES OF DETOXIFYING ENZYMES AND AChE INSENSITIVITY IN METHAMIDOPHOS RESISTANCE DEVELOPMENT AND DECLINE IN NILAPARVATA LUGENS

Institute of Scientific and Technical Information of China (English)

Ze-wenLiu; Zhao-junHan; Ling-chunZhang

2003-01-01

Methamidophos resistance of brown planthopper (Nilaparvata lugens Stal, BPH) was selected in laboratory. After successive selection for 9 generations, the selection was ceased by rearing BPH without contact with any insecticide for 9 generations. In the full course, the successive changes of esterase activity, MFO activity, GSTs activity and AChE insensitivity were analyzed. The results showed that the change of esterase activity was high correlated with that of methamidophos in the full course, which indicated that esterase played very important role both in the resistance development and in the resistance decline. However, the change of AChE insensitivity only significantly correlated with that of resistance in the development stage, and the change of MFO activity or GSTs activity only significantly correlated with that of the resistance in the decline stage, which indicated the changes of AChE insensitivity, MFO activity or GSTs activity only played some roles in different stages of the resistance change.

The Role of AChE in Swimming Behavior of Daphnia magna: Correlation Analysis of Both Parameters Affected by Deltamethrin and Methomyl Exposure

Directory of Open Access Journals (Sweden)

Qing Ren

2017-01-01

Full Text Available The unpredictable toxicity of insecticides may cause behavior disorder of biological organisms. In order to assess the role of acetylcholinesterase (AChE in swimming behavior of Daphnia magna, a correlation analysis of both parameters in 24 h exposure of deltamethrin (DM and methomyl (MT was investigated. The behavior responses of D. magna in DM (13.36 μg/L and 33.40 μg/L and MT (19.66 μg/L and 49.15 μg/L suggested that recovery behavior in the adjustment phase was crucial, and behavior homeostasis provided them with an optimal way to achieve a wider tolerance against environmental stress. During the experiment, positive effects on AChE activity occurred in the beginning of the exposure. Even though the de novo synthesis of AChE in D. magna might help it recover, the AChE inhibition in different treatments could be observed. Some induction effects on AChE activity at the beginning of exposure occurred, and a 50% decrease may cause toxic effects on behavior. In most treatments, the results showed that both behavior strength and AChE activity stayed in the same field within a correlation circle. These results illustrated that the environmental stress caused by both DM and MT could inhibit AChE activity and subsequently induce a stepwise behavior response, though both pesticides affect it as direct and indirect inhibitors, respectively.

Taeniases and cysticercosis in Indonesia: past and present situations.

Science.gov (United States)

Wandra, Toni; Ito, Akira; Swastika, Kadek; Dharmawan, Nyoman S; Sako, Yasuhito; Okamoto, Munehiro

2013-11-01

The main aim of this study is to overview the past and present situations of human taeniases and cysticercosis in Indonesia and including future perspectives. Through joint projects from 1996, we have confirmed the occurrence of Taenia saginata (beef tapeworm) in Bali, of Taenia solium (pork tapeworm) mainly in Papua and sporadically in Bali, and of Taenia asiatica in North Sumatra. These taeniases were caused through eating uncooked pork and pig viscera for T. solium and T. asiatica, respectively, and beef for T. saginata. The distribution of these tapeworms in Indonesia is basically highly restricted by the traditional cultural and religious backgrounds in each island. T. saginata is relatively common in Bali although people consume pork 'lawar' more than beef 'lawar'. Taeniases due to T. saginata or T. asiatica and T. solium and cysticercosis due to T. solium have also been sporadically reported in some other islands. Among these species, T. solium is exceptional since humans can be infected not only by larval stages (cysticerci) in pork but also by eggs released from human tapeworm carriers. Cysticercosis has been confirmed in Indonesia in humans, pigs and even dogs.

3D Agro-ecological Land Use Planning Using Surfer Tool for Sustainable Land Management in Sumani Watershed, West Sumatra Indonesia

Directory of Open Access Journals (Sweden)

Aflizar

2013-09-01

Full Text Available Estimation of soil erosion 3D (E3D provides basic information that can help manage agricultural areas sustainably, which has not been sufficiently conducted in Indonesia. Sumani watershed is main rice production area in West Sumatra which has experienced environmental problem such as soil erosion and production problem in recent years. 3D Agro-ecological land use planning based on soil erosion 3D hazard and economic feasibility analyses consist of production cost and prize data for each crop. Using a kriging method in Surfer tool program, have been developed data base from topographic map, Landsat TM image, climatic data and soil psychochemical properties. Using these data, the Universal Soil Loss Equation was used for spatial map of soil erosion 3D and proposed a 3D agro-ecological land use planning for sustainable land management in Sumani watershed. A 3D Agro-ecological land use planning was planned under which the land use type would not cause more than tolerable soil erosion (TER and would be economically feasible. The study revealed that the annual average soil erosion from Sumani watershed was approximately 76.70 Mg ha-1yr-1 in 2011 where more than 100 Mg ha-1yr-1 was found on the cultivated sloping lands at agricultural field, which constitutes large portion of soil erosion in the watershed. Modification of land use with high CP values to one with lower CP values such as erosion control practices by reforestation, combination of mixed garden+beef+chicken (MBC, terrace (TBC or contour cropping+beef+chicken (CBC and sawah+buffalo+chicken (SBC could reduce soil erosion rate by 83.2%, from 76.70 to 12.9 Mg ha-1 yr-1, with an increase in total profit from agricultural production of about 9.2% in whole Sumani watershed.

First record of a Tachaea species from Sulawesi (Indonesia) with description of its manca stage (Isopoda, Flabellifera, Corallanidae)

OpenAIRE

Bowman, Thomas E.; Botosaneanu, Lazare

1992-01-01

A corallanid isopod in the manca stage (lacking pereopod 7), collected from alluvial gravel along the Batui River in Sulawesi, Indonesia, and identified questionably as Tachaea lacustris Weber, 1892, is illustrated and described in detail. Tachaea lacustris was known previously only from freshwater lakes in Sumatra and Java. Its presence in river alluvial gravel should not be interpreted as possible adaptation to the hyporheic habitat.

Emergence of Melioidosis in Indonesia and Today’s Challenges

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Patricia M. Tauran

2018-03-01

Full Text Available A recent modeling study estimated that there could be as many as 20,000 human melioidosis cases per year in Indonesia, with around 10,000 potential deaths annually. Nonetheless, the true burden of melioidosis in Indonesia is still unknown. The Indonesia Melioidosis Network was formed during the first melioidosis workshop in 2017. Here, we reviewed 101 melioidosis cases (99 human and two animal cases previously reported and described an additional 45 human melioidosis cases. All 146 culture-confirmed cases were found in Sumatra (n = 15, Java (n = 104, Kalimantan (n = 15, Sulawesi (n = 11 and Nusa Tenggara (n = 1. Misidentification of Burkholderia pseudomallei was not uncommon, and most cases were only recently identified. We also evaluated clinical manifestations and outcome of recent culture-confirmed cases between 2012 and 2017 (n = 42. Overall, 15 (36% cases were children (age <15 years and 27 (64% were adults (age ≥15 years. The overall mortality was 43% (18/42. We conducted a survey and found that 57% (327/548 of healthcare workers had never heard of melioidosis. In conclusion, melioidosis is endemic throughout Indonesia and associated with high mortality. We propose that top priorities are increasing awareness of melioidosis amongst all healthcare workers, increasing the use of bacterial culture, and ensuring accurate identification of B. pseudomalleiand diagnosis of melioidosis.

Selenofuranoside Ameliorates Memory Loss in Alzheimer-Like Sporadic Dementia: AChE Activity, Oxidative Stress, and Inflammation Involvement

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Cristiano Chiapinotto Spiazzi

2015-01-01

Full Text Available Alzheimer’s disease (AD is becoming more common due to the increase in life expectancy. This study evaluated the effect of selenofuranoside (Se in an Alzheimer-like sporadic dementia animal model. Male mice were divided into 4 groups: control, Aβ, Se, and Aβ + Se. Single administration of Aβ peptide (fragments 25–35; 3 nmol/3 μL or distilled water was administered via intracerebroventricular (i.c.v. injection. Selenofuranoside (5 mg/kg or vehicle (canola oil was administered orally 30 min before Aβ and for 7 subsequent days. Memory was tested through the Morris water maze (MWM and step-down passive-avoidance (SDPA tests. Antioxidant defenses along with reactive species (RS were assessed. Inflammatory cytokines levels and AChE activity were measured. SOD activity was inhibited in the Aβ group whereas RS were increased. AChE activity, GSH, and IL-6 levels were increased in the Aβ group. These changes were reflected in impaired cognition and memory loss, observed in both behavioral tests. Se compound was able to protect against memory loss in mice in both behavioral tests. SOD and AChE activities as well as RS and IL-6 levels were also protected by Se administration. Therefore, Se is promising for further studies.

Real-time forecasting of the April 11, 2012 Sumatra tsunami

Science.gov (United States)

Wang, Dailin; Becker, Nathan C.; Walsh, David; Fryer, Gerard J.; Weinstein, Stuart A.; McCreery, Charles S.; ,

2012-01-01

The April 11, 2012, magnitude 8.6 earthquake off the northern coast of Sumatra generated a tsunami that was recorded at sea-level stations as far as 4800 km from the epicenter and at four ocean bottom pressure sensors (DARTs) in the Indian Ocean. The governments of India, Indonesia, Sri Lanka, Thailand, and Maldives issued tsunami warnings for their coastlines. The United States' Pacific Tsunami Warning Center (PTWC) issued an Indian Ocean-wide Tsunami Watch Bulletin in its role as an Interim Service Provider for the region. Using an experimental real-time tsunami forecast model (RIFT), PTWC produced a series of tsunami forecasts during the event that were based on rapidly derived earthquake parameters, including initial location and Mwp magnitude estimates and the W-phase centroid moment tensor solutions (W-phase CMTs) obtained at PTWC and at the U. S. Geological Survey (USGS). We discuss the real-time forecast methodology and how successive, real-time tsunami forecasts using the latest W-phase CMT solutions improved the accuracy of the forecast.

Benefit Analysis of Implementation of Alternative SO2 Quality Standards on Acute Respiratory Syndrome (ARI Incidence Reduction in Indonesia

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Muhamad Nizar

2014-12-01

Full Text Available Indonesia Quality Standard (QS for ambient SO2 for 1 hour time average i.e. 900 μg/m3(equivalent to 360μg/m3in24 hour time average regulated in the Government Regulation No. 41 of 1999 is the most loose compared to the ambient SO2 standards of other countries in the world including WHO QS guideline. This QS is not expected to guarantee the protection of public health in Indonesia. Therefore more stringent QS alternative for ambient SO2 is required. This research examines benefit values in public health aspect if Indonesia tightens its ambient SO2 QS. Two alternative QS for SO2 are used i.e196 μg/m3(equivalent to 78μg/m3in24 hour time average referring to U.S. EPA and 750μg/m3(equivalent to 360μg/m3in24 hour time average referring to PUSARPEDAL. First step is to map distribution of SO2 ambient concentrations in Indonesia. The result indicates that Provinces of Jakarta and Banten have exceeded both alternative QS while Provinces of Yogyakarta, West Java, Central Java, East Java, Bali, and North Sumatra only exceed the alternative QS of 196μg/m3. From the public health aspect, by attaining to the alternative QS of 750μg/m3, Jakarta and Banten will reduce incidence of ARI by 95% and 98%. By attaining to the alternative QS of 196μg/m3, East Java, Bali and North Sumatra will reduce the incidence of ARI by 59%, 51%, and 5%.

NOTES ON THE PALM FLORA OF CENTRAL SUMATRA

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John Dransfield

2014-01-01

Full Text Available In July and August 1972, I spent five weeks on an expedition to study rattans and other palms in the provinces of Jambi and West Sumatra. This central area of Sumatra was chosen because expeditions have already been made to South Sumatra in February 1971 and March 1972 and to North Sumatra and Aceh with the Kyoto University Expedition in August 1971, and therefore collections made in this central area would link up collections from the south and north and would hence add considerably to our knowledge of the palm flora of this rich island. After advice from the Department of Nature Conservation in Jambi and from Dr. M. Jacobs in Rijksherbarium (Leiden had been considered, it was decided to work westwards from Berbak Nature Reserve on the east coast near Nipah Panjang, to the Bukit Barisan, the main range of Sumatra, to Gunung Kerinci Nature Reserve and G. Tujuh near Sungai Penuh and from there, across the western part of the Bukit Barisan to Padang and Bukittinggi. From Bukittinggi it was planned to visit the Kafflesia arnoldii Nature Reserve at Batang Palupuh, and then return to Jambi by way of Muara Tebo and Muara Tembesi, where reputedly there still exists lowland forest. By more or less confining our collecting activities to the normally neglected Palmae it was hoped that within the time available a large area could be covered reasonably, and a palm transect for central Sumatra made. Two assistants from Bogor accompanied me to help in the difficult task of collecting rattans: Dedy Darnaedi (Herbarium Bogoriense and Abdul Hanan (Kebun Raya. These assistants were also given individual collecting assignments as part of a scheme for training assistants in field botany. Dedy was to collect Pteridophyta and Hanan to collect material for growing in the Kebun Raya. Soetrisno Soewoko, head of Nature Conservation in Jambi accompanied us throughout tha expedition.

Removal of Procion Red MX-5B from songket's industrial wastewater in South Sumatra Indonesia using activated carbon-Fe3O4 composite

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Poedji Loekitowati Hariani

2018-07-01

Full Text Available Songket is traditional costume in South Sumatra, Indonesia. This study investigates the feasibility of using activated carbon-Fe3O4 composite to adsorb the Procion Red MX-5B dye from songket's industrial wastewater. The adsorbent was characterized using the surface area analyzer, X ray Diffraction, Scanning Electron Microscopy, Energy Dispersive X-ray Analysis, Fourier Transform Infrared and Vibrating Sample Magnetometer. The effects of pH, weight of composite and the contact time were evaluated to determine the adsorption efficiency. The kinetic and isotherm were carried out to evaluate the adsorption behavior of composite. The toxicity level of songket's industrial wastewater was measured using Tilapia fishes as the biological indicator. The 24-h LC50 was calculated using Probit analysis method. The results show that the adsorption process of Procion Red MX-5B using activated carbon-Fe3O4 composite follows a pseudo first order kinetic and the experimental data show a good correlation with Freundlich isotherm. Songket's industrial wastewater has the 24-h LC50 for Tilapia of 5.6% ± 0.6. After treatment using activated carbon-Fe3O4 composite at pH 6 and contact time of 50 min, the adsorbent can reduce concentration of the Procion Red MX-5B by 94% and chemical oxygen demand by 96%. The experimental results indicate that the activated carbon-Fe3O4 composite is effective as an adsorbent for the treatment of songket's industrial wastewater.

Proposed seismic hazard maps of Sumatra and Java islands and ...

Indian Academy of Sciences (India)

(3-D) seismic source models (fault source model) using the latest research works regarding the tec- tonic setting of Sumatra and ... is selected because this city is the main business ... and Sumatra, the improvements of the method in seismic ...

Design, synthesis and evaluation of some N-methylenebenzenamine derivatives as selective acetylcholinesterase (AChE) inhibitor and antioxidant to enhance learning and memory.

Science.gov (United States)

Shrivastava, Sushant K; Srivastava, Pavan; Upendra, T V R; Tripathi, Prabhash Nath; Sinha, Saurabh K

2017-02-15

Series of some 3,5-dimethoxy-N-methylenebenzenamine and 4-(methyleneamino)benzoic acid derivatives comprising of N-methylenebenzenamine nucleus were designed, synthesized, characterized, and assessed for their acetylcholinesterase (AChE), butyrylcholinesterase (BChE) inhibitory, and antioxidant activity thereby improving learning and memory in rats. The IC 50 values of all the compound along with standard were determined on AChE and BChE enzyme. The free radical scavenging activity was also assessed by in vitro DPPH (2,2-diphenyl-1-picryl-hydrazyl) and hydrogen peroxide radical scavenging assay. The selective inhibitions of all compounds were observed against AChE in comparison with standard donepezil. The enzyme kinetic study of the most active compound 4 indicated uncompetitive AChE inhibition. The docking studies of compound 4 exhibited the worthy interaction on active-site gorge residues Phe330 and Trp279 responsible for its high affinity towards AChE, whereas lacking of the BChE inhibition was observed due to a wider gorge binding site and absence of important aromatic amino acids interactions. The ex vivo study confirmed AChE inhibition abilities of compound 4 at brain site. Further, a considerable decrease in escape latency period of the compound was observed in comparison with standard donepezil through in vivo Spatial Reference Memory (SRM) and Spatial Working Memory (SWM) models which showed the cognition-enhancing potential of compound 4. The in vivo reduced glutathione (GSH) estimation on rat brain tissue homogenate was also performed to evaluate free radical scavenging activity substantiated the antioxidant activity in learning and memory. Copyright © 2017 Elsevier Ltd. All rights reserved.

Dominant seismic sources for the cities in South Sumatra

Science.gov (United States)

Sunardi, Bambang; Sakya, Andi Eka; Masturyono, Murjaya, Jaya; Rohadi, Supriyanto; Sulastri, Putra, Ade Surya

2017-07-01

Subduction zone along west of Sumatra and Sumatran fault zone are active seismic sources. Seismotectonically, South Sumatra could be affected by earthquakes triggered by these seismic sources. This paper discussed contribution of each seismic source to earthquake hazards for cities of Palembang, Prabumulih, Banyuasin, OganIlir, Ogan Komering Ilir, South Oku, Musi Rawas and Empat Lawang. These hazards are presented in form of seismic hazard curves. The study was conducted by using Probabilistic Seismic Hazard Analysis (PSHA) of 2% probability of exceedance in 50 years. Seismic sources used in analysis included megathrust zone M2 of Sumatra and South Sumatra, background seismic sources and shallow crustal seismic sources consist of Ketaun, Musi, Manna and Kumering faults. The results of the study showed that for cities relatively far from the seismic sources, subduction / megathrust seismic source with a depth ≤ 50 km greatly contributed to the seismic hazard and the other areas showed deep background seismic sources with a depth of more than 100 km dominate to seismic hazard respectively.

Towards the challenging REE exploration in Indonesia

Science.gov (United States)

Setiawan, Iwan

2018-02-01

Rare earth elements (REE) are the seventeen elements, including fifteen from 57La to 71Lu, in addition to 21Sc and 39Y. In rock-forming minerals, rare earth elements typically occur in compounds as trivalent cations in carbonates, oxides, phosphates, and silicates. The REE occur in a wide range of rock types: igneous, sedimentary and metamorphic rocks. REE are one of the critical metals in the world. Their occurrences are important to supply the world needs on high technology materials. Indonesia has a lot of potential sources of REE that are mainly from residual tin mining processes in Bangka islands, which are associated with radioactive minerals e.g. monazite and xenotime. However, the REE from monazite and xenotime are difficult to extract and contain high radioactivity. Granitoids are widely distributed in Sumatra, Sulawesi, Kalimantan and Papua. They also have a very thick weathering crusts. Important REE-bearing minerals are allanite and titanite. Their low susceptibilities during weathering result an economically potential REE concentration. I-/A- type granitoids and their weathered crusts are important REE sources in Indonesia. Unfortunately, their distribution and genesis have not been deeply studied. Future REE explorations challenge are mainly of the granitoids their weathered crusts. Geochemical and mineralogical characterization of type of granitoids and their weathered crusts, the hydrothermally altered rocks, and clear REE regulation will help discover REE deposits in Indonesia.

大白鼠海马神经元NOS与AChE活性的研究%Study on the NOS and AChE Activity in the Hippocampus Neurons of Rat

Institute of Scientific and Technical Information of China (English)

夏保芦; 杨荣; 杨友华; 杨敏; 黄丹

2005-01-01

目的:观察大白鼠海马不同亚区一氧化氮合酶(NOS)与乙酰胆碱酯酶(AChE)阳性神经元的活性.方法:分别采用还原型尼克酰胺嘌呤二核苷酸脱氢酶(NADPH-d)和乙酰胆碱酯酶(AChE)组织化学方法对大白鼠海马不同亚区NOS和AChE阳性神经元的分布以及活性进行研究.结果:海马不同亚区均含有NOS和AChE阳性神经元,其中CA2区NOS呈强阳性反应,CA3区AChE呈强阳性反应.结论:实验表明,NOS和AChE阳性神经元广泛分布于大白鼠海马不同亚区,为进一步探讨海马的学习记忆功能机制提供了形态学佐证.

Verbal Communication Culture and Local Wisdom: The Value Civilization of Indonesia Nation

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Tina Kartika

2016-11-01

Full Text Available Indonesia is a nation with cultural diversity and area. This caused a lot of the uniqueness of culture in everyday life. This uniqueness was generally a positive value to maintain the harmony of human beings and nature. The discussion of this article was the verbal communication, the study of the wisdom of the nation speech-language Indonesia, and local wisdom in civilization. The words expressed in the local wisdom among others are fearless (need fear only God Almighty, self-sacrificing or spirit of nationalism (patriotism, orderly, loyal, affectionate, hardworking, consensus, mutual help, and creative. Positive values here needed to be crystallized in people’s lives; it would be the identifier of the Indonesian people. This research was conducted in five districts of Pagaralam, South Sumatra. The method used was qualitative. Data collection techniques included participant observer/observation, observation without participation, in-depth interviews, and documentation. This article finds that if local wisdom actually exists in everyday life, the nation of Indonesia has carved beauty behave in civilization itself. The local wisdom of the nation begins values, the rule in the family, and then developed in the community. A positive value of local wisdom is the identifier of civilized society and the need to preserve Indonesia. 

Effects of EGCG and Chlorpyrifos on the Mortality, AChE and GSH of Adult Zebrafish: Independent and Combination

Science.gov (United States)

Zhang, Rong; Zhang, Jian; Gao, Qian; Guo, Nichun

2018-01-01

Chlorpyrifos is a neurotoxic agent and also causes oxidative stress in the body. EGCG is a typical strong antioxidant and has been reported to be neuroprotective. Our study investigated the mortality, the activity of acetylcholinesterase (AChE) in the brain and glutathione (GSH) in the liver of the adult Zebrafish in present of Chlorpyrifos and EGCG independent and combination. The results indicated that after the addition of EGCG, the mortality of zebrafish induced by Chlorpyrifos was reduced and the activity of AChE and glutathione (GSH) inhibited by Chlorpyrifos in zebrafish was significantly increased, which demonstrated that EGCG inhibited the toxicity Chlorpyrifos to zebrafish. The inhibition was dependent on the concentration of EGCG and Chlorpyrifos, which was not shown a gradual change trend but a complex situation.

LESSON LEARNED FROM MANGROVE REHABILITATION PROGRAM IN INDONESIA

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Cecep Kusmana

2017-07-01

Full Text Available Indonesia as an archipelagic country more than 17,504 islands with the length of coastline estimated at 95,181 km bears mangroves from several meters to several kilometers. They grow extensively in the five big islands (Jawa, Sumatra, Kalimantan, Sulawesi, Papua. At the year of 2009, Agency of Survey Coordination and National Mapping (Bakosurtanal of Indonesia reported the existing mangrove forest area in Indonesia of about 3,244,018 ha, however Directorate General of Land Rehabilitation and Social Forestry, Ministry of Forestry (Ditjen RLPS MoF of Indonesia at 2007 reported about 7,758,411 ha of mangrove area in Indonesia (including existing vegetated mangrove area. It was further reported that those mangroves were 30.7% in good condition, 27.4% moderate-destroyed, and 41.9% heavy-destroyed. In order to rehabilitate destroyed mangrove ecosystems, Indonesia applies at least three type of planting designs (square planting design, zig zag planting design, and cluster planting design and eight planting techniques (“banjar harian” technique, bamboo pole technique, guludan technique, water break technique, huge polybag technique, ditch muddy technique, huge mole technique, cluster technique. Generally, in Indonesia Rhizophora spp. are used for mangrove rehabilitation and/or restoration with the spacing of 1x1 m spending varied planting cost based on the site local condition and planting technique used. The mangrove planting ranged from about Rp. 14.2 million using propagules to Rp. 18.5 million using cultured seedlings. Recently, local community used to utilizing associated mangrove aquatic fauna for supporting their daily life as well as utilizing mangrove habitat for multipurpose uses through agroforestry techniques (silvofishery, agrosilvofishery, agrosilvopastoralfishery systems. So that, the good mangrove ecosystem serves luxurious both flora and fauna species (biodiversity as well as their abundance for significantly

Elite Capture and Corruption in two Villages in Bengkulu Province, Sumatra.

Science.gov (United States)

Lucas, Anton

This paper examines leadership, elite capture and corruption in two villages in Sumatra. It compares implementation and outcomes of several conservation and development projects in the context of democratization and decentralization reforms introduced in Indonesia since 1998. In examining aspects of elite control and elite capture, this paper focuses on the activities of local elites, particularly village officials, who use their positions to monopolize planning and management of projects that were explicitly intended to incorporate participatory and accountability features. While elites' use of authority and influence to benefit personally from their roles clearly reflects elite capture, there are nonetheless members of elite groups in these case studies who use their control of projects to broad community benefit. In both villages there is considerable friction between villagers and elites as well as among members of the local elite themselves over control of local resources. Differences in the structure of these cross-cutting internal relationships and of ties between local authorities and outside government and non-government agents largely explain the differences in degree of elite capture and its outcomes in the two cases.

Common SAR Derived from Linear and Non-linear QSAR Studies on AChE Inhibitors used in the Treatment of Alzheimer's Disease.

Science.gov (United States)

Pulikkal, Babitha Pallikkara; Marunnan, Sahila Mohammed; Bandaru, Srinivas; Yadav, Mukesh; Nayarisseri, Anuraj; Sureshkumar, Sivanpillai

2017-11-14

Deficits in cholinergic neurotransmission due to the degeneration of cholinergic neurons in the brain are believed to be one of the major causes of the memory impairments associated with AD. Targeting acetyl cholinesterase (AChE) surfaced as a potential therapeutic target in the treatment of Alzheimer's disease. The present study is pursued to develop quantitative structure activity relationship (QSAR) models to determine chemical descriptors responsible for AChE activity. Two different sets of AChE inhibitors, dataset-I (30 compounds) and dataset-II (20 compounds) were investigated through MLR aided linear and SVM aided non-linear QSAR models. The obtained QSAR models were found statistically fit, stable and predictive on validation scales. These QSAR models were further investigated for their common structure-activity relationship in terms of overlapping molecular descriptors selection. Atomic mass weighted 3D Morse descriptors (MATS5m) and Radial Distribution Function (RDF045m) descriptors were found in common SAR for both the datasets. Electronegativity weighted (MATS5e, HATSe, and Mor17e) descriptors have also been identified in regulative roles towards endpoint values of dataset-I and dataset-II. The common SAR identified in these linear and non-linear QSAR models could be utilized to design novel inhibitors of AChE with improved biological activity. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

New insight on the Toba volcano super eruption (Sumatra Island, Indonesia) from BAR-9425 core.

Science.gov (United States)

Caron, B.; del Manzo, G.; Moreno, E.; Annachiara, B.; Baudin, F.; Bassinot, F. C.; Villemant, B.

2017-12-01

The famous 73 ka Toba eruption has produced about 2800 km3 of magma and is considered as one of the largest known eruptions during the Quaternary (Rose and Chesner, 1990). The BAR-9425 piston core collected during the 1994 joint French-Indonesian BARAT Cruise in the north Sumatra Island has recorded the volcano history of Toba from 60 to 100 ka (including the 73 ka Young Toba Tuff (YTT)). Tephra layers within this sediment core have been systematically studied using a combined analysis including stable isotope (δ18O, van der Kaars et al., 2012), high resolution tephrostratigraphic, morphological and a major-trace element studies. Our preliminary results show that not only one major eruption occurred between 60 and 100 ka but probably 11 distinct eruptions occurred. The 11 eruptions display an homogeneous major element composition. The oldest tephra with an estimated age of 101 ka, have a rhyolitic composition and 30% of relative abundance of volcanic glass shards. The other eruptive phases are dated at: 91,5-89,2 ka with a maximum of 16% of volcanic tephra; 85,7-84,8 ka with 64%; 81,8 ka with 22%; 74,4 ka with 43%, 72,3 ka with 89%, 71,4 ka with 92%; 68,9% with 96%; 66,5 ka with 94%; 65,2 ka with 75% and 63,1-60,3 ka with a maximum of 96% of volcanic tephra respectively (ages were calculated with a constant sediment rate of 4,3 cm/ka from data from van der Kaars et al., 2012). Some of these eruptions have had direct effect on regional vegetation as suggested by Van der Kaars et al. (2012) who propose that the gradual expansion of pine cover for the 7000 years following the eruption, is a consequence of the ash deposit from the 89 ka eruption. Our detailed tephrostratigraphy study of Toba eruptions will help to understand the impact on the ecosystems of northern Sumatra and on global climate change. Moreover, we expect to correlate the new tephra layers of Toba volcano to other sites by using AL-ICP-MS traces analyses and to use it as chronological makers.

A comprehensive field and laboratory study of scale control and scale squeezes in Sumatra, Indonesia

Energy Technology Data Exchange (ETDEWEB)

Oddo, J.E.; Reizer, J.M.; Sitz, C.D. [Champion Technologies, Inc., Houston, TX (United States); Setia, D.E.A. [FMT Production Duri P.T. Caltex Pacific Indonesia (Indonesia); Hinrichsen, C.J. [Texaco Panama, Bellaire, TX (United States); Sujana, W. [P.T. Champion Kumia Djaja Technologies, Jakarta (Indonesia)

1999-11-01

Scale squeezes were performed on thirteen wells in the Duri Field, Sumatra. At the time the squeezes were completed, seven were designed to be `Acid Squeezes` and six were designed to be `Neutral Squeezes.` In the course of preparing for the scale squeezes, produced waters were collected and analyzed. In addition, scale inhibitor evaluations, and inhibitor compatibility studies were completed. Simulated squeezes were done in the laboratory to predict field performance. The methodologies and results of the background work are reported. In addition, the relative effectiveness of the two sets of squeezes is discussed. The inhibitor flowback concentrations alter the squeezes, in all cases, can be explained using speciation chemistry and the amorphous and crystalline phase solubilities of the inhibitor used. The wells squeezed with a more acidic inhibitor have more predictable and uniform inhibitor return concentration curves than the wells squeezed with a more neutral scale inhibitor.

Crystal structure of Lymnaea stagnalis AChBP complexed with the potent nAChR antagonist DHβE suggests a unique mode of antagonism.

Directory of Open Access Journals (Sweden)

Azadeh Shahsavar

Full Text Available Nicotinic acetylcholine receptors (nAChRs are pentameric ligand-gated ion channels that belong to the Cys-loop receptor superfamily. These receptors are allosteric proteins that exist in different conformational states, including resting (closed, activated (open, and desensitized (closed states. The acetylcholine binding protein (AChBP is a structural homologue of the extracellular ligand-binding domain of nAChRs. In previous studies, the degree of the C-loop radial extension of AChBP has been assigned to different conformational states of nAChRs. It has been suggested that a closed C-loop is preferred for the active conformation of nAChRs in complex with agonists whereas an open C-loop reflects an antagonist-bound (closed state. In this work, we have determined the crystal structure of AChBP from the water snail Lymnaea stagnalis (Ls in complex with dihydro-β-erythroidine (DHβE, which is a potent competitive antagonist of nAChRs. The structure reveals that binding of DHβE to AChBP imposes closure of the C-loop as agonists, but also a shift perpendicular to previously observed C-loop movements. These observations suggest that DHβE may antagonize the receptor via a different mechanism compared to prototypical antagonists and toxins.

The local knowledge of medicinal plants trader and diversity of medicinal plants in the Kabanjahe traditional market, North Sumatra, Indonesia.

Science.gov (United States)

Silalahi, Marina; Nisyawati; Walujo, Eko Baroto; Supriatna, Jatna; Mangunwardoyo, Wibowo

2015-12-04

Market is the main place for transactions of medicinal plants and traditional ingredients by local community in the Karo regency, North Sumatra, Indonesia. This is the first study to document the local knowledge of traders on and the diversity of the medicinal plants. The investigation was carried out in the Kabanjahe traditional market, in the Karo regency. The research goal was to reveal the local knowledge, diversity and utilization of medicinal plants, which have been traded in the Kabanjahe traditional market, as a basis for conservation efforts. The study was conducted through ethnobotanical approach using market surveys. All traders of medicinal plants were surveyed applying in-depth interviews and participative observations. Data were analyzed qualitatively using descriptive statistics. The diversity of medicinal plants was expressed in term of the Shannon-Wiener diversity index (H'), whereas the similarity among traders was indicated by Jaccard index (Ji). Traders of medicinal plants stored the simplicia of medicinal plants in chest of drawers, plastic baskets, plastic bags, and in the air by suspending them from the the stall ceilings. We recorded 344 species, 217 genera and 90 families of medicinal plants. Those that were sold mostly belong to Zingeberaceae (20 species), Poaceae (19 species), and Asclepiadaceae (17 species), and the species received high consumers demand, mostly belong to Zingiberaceae, Rutaceae, and Asclepidiaceae. Asclepidiaceae was used to treat diseases like cancer and heart problems. The Shannon-Wiener diversity index of medicinal plants at the Kabanjahe traditional market was high (H'= 5.637). The high Jaccard similarity index (Ji>0.56) suggested that the traders were trading similar species of medicinal plants. Kabanjahe traditional market is the center for the sale of of medicinal plants as traditional ingredients. Several species are well known for their pharmacological properties but others, [such as: Dischidia imbricata (Blume

Indonesia's great frontier and migration policy.

Science.gov (United States)

Maloney, C

1987-01-01

The population of Indonesia is 175 million, of which 65% live in Java. Java has only 7% of the land area, causing a population density of 2,000/square mile. This has lead the government to introduce a policy of transmigration which encourages people to move from Java to the larger outer islands. In the last 35 years 4.3 million people have moved from Java to Sumatra, Borneo, Celebes, and Irian Jaya. The total area of Indonesia stretches over 3,200 miles and has 16,000 islands of which 1,000 are inhabited. It has vast resources of oil, lumber, rubber, tin, palm oil, copra, coffee, tea, pepper, cloves, nutmeg, and quinine. Indonesia is also rich in minerals, including coal, bauxite, iron ore, and gold. Even with a national family planning program, population growth has reached 2.1% a year. 3 other islands that people are induced to move from are Madura, Bali, and Lombok, although their population densities are less then Java. The small islands near Singapore are being developed and Batam will be a free port to compete with Hong Kong. The most intense migration has been to Kalimantan (Borneo) which has 4 provinces. The migration policy began in 1905 and by 1930 100,000 people, had moved to other islands; 600,000 people were relocated to plantations in Java for labor needs. In 1979-84, a more ambitious program costing 2.3 billion moved 1.5 million people. In the most recent 1984-89 plan, a goal of 3.1 million were to be relocated but due to budgetary restrictions only 150,000 families have moved. The main social issue addresses the domination of other people by Javanese, not only in numbers but cultural differences. Some observers say the real reason for migration is political in ensuring the boundaries and geographic integrity of Indonesia.

THE TRACES OF PROTO-LANGUAGES OF AUSTRONESIA IN SOME MODERN LANGUAGES IN SUMATRA

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Ermanto

2017-10-01

Full Text Available This study discusses the traces proto-languages of Austronesian in modern languages in Sumatra. Modern languages in Sumatra are the languages of the subgroups of Sumatra as part of a group which is an Austronesian Southwestern which is Western Austronesian group. The purpose of this study is to find and assess reflex etimon mother language of Austronesian present in some modern languages in the language of Sumatra namely Aceh, Batak Toba, Mandailaing language, language Kerinci, Minangkabau and Mentawai language. To find reflex (reflection mother language of Austronesian in several languages in Sumatra used comparative methods are qualitative. The use of the method is to reconstruct antarabahasa relationship based on the legacy of rank higher language that PAN into several languages with the lower rank (top-down reconstruction namely the Acehnese language, language Batak Toba, Mandailing language, language Kerinci, Minangkabau and Mentawai language. Research findings indicate that there are reflex (reflection etimon mother language of Austronesian in some modern languages in the language of Sumatra, Aceh, Batak Toba, Mandailaing language, language Kerinci, Minangkabau and Mentawai language. This indicates that all six of these languages is a derivative of the PAN.

Chlorpyrifos and Malathion have opposite effects on behaviors and brain size that are not correlated to changes in AChE activity

Science.gov (United States)

Richendrfer, Holly; Creton, Robbert

2015-01-01

Organophosphates, a type of neurotoxicant pesticide, are used globally for the treatment of pests on croplands and are therefore found in a large number of conventional foods. These pesticides are harmful and potentially deadly if ingested or inhaled in large quantities by causing a significant reduction in acetylcholinesterase (AChE) activity in the central and peripheral nervous system. However, much less is known about the effects of exposure to small quantities of the pesticides on neural systems and behavior during development. In the current study we used zebrafish larvae in order to determine the effects of two of the most widely used organophosphates, chlorpyrifos and malathion, on zebrafish behavior and AChE activity. Embryos and larvae were exposed to the organophosphates during different time points in development and then tested at 5 days post-fertilization for behavioral, neurodevelopmental and AChE abnormalities. The results of the study indicate that chlorpyrifos and malathion cause opposing behaviors in the larvae such as swim speed (hypoactivity vs. hyperactivity) and rest. Additionally, the pesticides affect only certain behaviors, such as thigmotaxis, during specific time points in development that are unrelated to changes in AChE activity. Larvae treated with malathion but not chlorpyrifos also had significantly smaller forebrain and hindbrain regions compared to controls by 5 days post-fertilization. We conclude that exposure to very low concentrations of organophosphate pesticides during development cause abnormalities in behavior and brain size. PMID:25983063

Chlorpyrifos and malathion have opposite effects on behaviors and brain size that are not correlated to changes in AChE activity.

Science.gov (United States)

Richendrfer, Holly; Creton, Robbert

2015-07-01

Organophosphates, a type of neurotoxicant pesticide, are used globally for the treatment of pests on croplands and are therefore found in a large number of conventional foods. These pesticides are harmful and potentially deadly if ingested or inhaled in large quantities by causing a significant reduction in acetylcholinesterase (AChE) activity in the central and peripheral nervous system. However, much less is known about the effects of exposure to small quantities of the pesticides on neural systems and behavior during development. In the current study we used zebrafish larvae in order to determine the effects of two of the most widely used organophosphates, chlorpyrifos and malathion, on zebrafish behavior and AChE activity. Embryos and larvae were exposed to the organophosphates during different time points in development and then tested at 5 days post-fertilization for behavioral, neurodevelopmental and AChE abnormalities. The results of the study indicate that chlorpyrifos and malathion cause opposing behaviors in the larvae such as swim speed (hypoactivity vs. hyperactivity) and rest. Additionally, the pesticides affect only certain behaviors, such as thigmotaxis, during specific time points in development that are unrelated to changes in AChE activity. Larvae treated with malathion but not chlorpyrifos also had significantly smaller forebrain and hindbrain regions compared to controls by 5 days post-fertilization. We conclude that exposure to very low concentrations of organophosphate pesticides during development cause abnormalities in behavior and brain size. Copyright © 2015 Elsevier Inc. All rights reserved.

Evaluation of mangrove reforestation and the impact to socioeconomic-cultural of community in Lubuk Kertang village, North Sumatra

Science.gov (United States)

Basyuni, M.; Harahap, MA; Wati, R.; Slmaet, B.; Thoha, AS; Nuryawan, A.; Putri, LAP; Yusriani, E.

2018-03-01

Mangrove forests in North Sumatera existed in the east coast of Sumatera Island and are rapidly threatened due to anthropogenic activities such as conversion for aquaculture, oil palm plantation, filling and use of mangrove for urban development. The present study describes the current and first-year evaluation on mangrove restoration and its impact to socio economic-cultural of community in Lubuk Kertang village, Langkat, North Sumatra, Indonesia. The rehabilitation was carried on December 2015 using direct planting of 6,000 Rhizophora apiculata propagules and May 2016 using 5,000 R. apiculata seedlings. The evaluation parameters of mangrove reforestation consist of seedling diameter and height, leaf thickness and number, and seedling growth rate. Ninety-two of 1,124 households were surveyed using Slovin formula to obtain community perspective on the socio-economic-cultural impact of reforestation. Results show that the growth rate for current and first-year evaluation was 93 and 86 %, respectively. By contrast, the height, diameter, and some leaves seedlings planting were shown better than the performance of propagules planting. No change in the green foliage plant thickness between both farming methods. The reforestation affected 71.74, 55.43 and 39.13% of economic, social, and cultural of Lubuk Kertang community, respectively. The data is likely to provide valuable information for mangrove reforestation in North Sumatra.

Pre-pregnancy body mass index and gestational weight gain and their effects on pregnancy and birth outcomes: a cohort study in West Sumatra, Indonesia.

Science.gov (United States)

Soltani, Hora; Lipoeto, Nur I; Fair, Frankie J; Kilner, Karen; Yusrawati, Y

2017-11-09

Indonesia has a considerably high incidence of maternal and infant mortality. The country has however been experiencing a social and economic transition, influencing its general population demographics and nutritional status including the state of health and nutrition of pregnant women. This study aimed to explore body mass index (BMI) and gestational weight gain (GWG), and their relationship with pregnancy outcomes in a sample of Indonesian pregnant women. This observational cohort study included a total of 607 pregnant women who were recruited in 2010 from maternity clinics in Western Sumatra, Indonesia. Multiple logistic and regression analyses were undertaken to compare pregnancy and birth outcomes for different BMI and GWG, using normal weight women and women with a recommended weight gain as the referent groups. The prevalence of underweight (BMI < 18.5 kg/m 2 ) in pregnancy was high at 20.1%; while 21.7% of women were overweight (BMI: 23.0-27.4 kg/m 2 ) and 5.3% obese (BMI ≥ 27.5 kg/m 2 ) using the Asian BMI classifications. The incidence of overweight (BMI: 25.0-29.9 kg/m 2 ) and obese (BMI ≥ 30.0 kg/m 2 ) according to the international BMI classifications were 13.5% and 1.1% respectively. The majority of women gained inadequate weight in pregnancy compared to the Institute of Medicine (IOM) recommendations, especially those who had a normal BMI. Birthweight adjusted mean difference aMD (95% confidence interval) 205 (46,365) and the odds of macrosomia adjusted odds ratio aOR 13.46 (2.32-77.99) significantly increased in obese women compared to those with a normal BMI. Birthweight aMD -139 (-215, -64) significantly decreased in women with inadequate GWG compared to those with recommended GWG, while SGA aOR 5.44 (1.36, 21.77) and prematurity aOR 3.55 (1.23, 10.21) increased. Low nutritional status and inadequate GWG remain a cause for concern in these women. The higher odds of macrosomia with increasing maternal BMI and higher odds of

Recovery of a lowland dipterocarp forest twenty two years after selective logging at Sekundur, Gunung Leuser National Park, North Sumatra, Indonesia

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Dolly - Priatna

2006-12-01

Full Text Available PRIATNA, D.; KARTAWINATA, K.; ABDULHADI, R. 2004. Recovery of a lowland dipterocarp forest twenty two years after selective logging at Sekundur, Gunung Leuser National Park, North Sumatra, Indonesia. Reinwardtia 12 (3: 237–255. — A permanent 2-ha plot of lowland forest selectively logged in 1978 at Sekundur, Gunung Leuser National Park, which is also a Biosphere Reserve and a World Heritage Site, North Sumatra, was established and investigated in 1982. It was re-examined in 2000, where remeasurement and reidentification of all trees with DBH 10 cm were made. The areas of gap, building and mature phases of the canopy were also measured and mapped. Within this plot, 133 species, 87 genera and 39 families were recorded, with the total number of trees of 1145 or density of 572.5/ha. Euphorbiaceae was the richest family with 18 species (13.5 % of the total and total number of trees of 248 (21.7 % of the total or density of 124 trees/ha. The most important families were Dipterocarpaceae with IV (Importance Value = 52.0, followed by Euphorbiaceae with IV = 51.8. The most prevalent species was Shorea kunstleri (Dipterocarpaceae with IV =24.4, followed by Macaranga diepenhorstii (Euphorbiaceae with IV = 12.4. They were the species with highest density, 34 trees/ha and 23.5 trees/ha, respectively. During the period of 18 years there has been no shift in the richest families, most important families and most important species. Euphorbiaceae was the richest family and Dipterocarpaceae was the most important family, with Shorea kunstleri as the most important species with highest importance value throughout the period. The number of species increased from 127 to 133 with increase in density by 36.8% , from 418.5 trees/ha to 572.5 trees/ha. The mortality was 25.57 % or 1.4 % per year. The diameter class distribution indicated that the forest recovery has not been complete. Trees were small, comprising 67.6 % with diameters of 10-20 cm and only two trees

Fire emissions and regional air quality impacts from fires in oil palm, timber, and logging concessions in Indonesia

International Nuclear Information System (INIS)

Marlier, Miriam E; DeFries, Ruth S; Kim, Patrick S; Koplitz, Shannon N; Jacob, Daniel J; Mickley, Loretta J; Myers, Samuel S

2015-01-01

Fires associated with agricultural and plantation development in Indonesia impact ecosystem services and release emissions into the atmosphere that degrade regional air quality and contribute to greenhouse gas concentrations. In this study, we estimate the relative contributions of the oil palm, timber (for wood pulp and paper), and logging industries in Sumatra and Kalimantan to land cover change, fire activity, and regional population exposure to smoke concentrations. Concessions for these three industries cover 21% and 49% of the land area in Sumatra and Kalimantan respectively, with the highest overall area in lowlands on mineral soils instead of more carbon-rich peatlands. In 2012, most remaining forest area was located in logging concessions for both islands, and for all combined concessions, there was higher remaining lowland and peatland forest area in Kalimantan (45% and 46%, respectively) versus Sumatra (20% and 27%, respectively). Emissions from all combined concessions comprised 41% of total fire emissions (within and outside of concession boundaries) in Sumatra and 27% in Kalimantan for the 2006 burning season, which had high fire activity relative to decadal emissions. Most fire emissions were observed in concessions located on peatlands and non-forested lowlands, the latter of which could include concessions that are currently under production, cleared in preparation for production, or abandoned lands. For the 2006 burning season, timber concessions from Sumatra (47% of area and 88% of emissions) and oil palm concessions from Kalimantan (33% of area and 67% of emissions) contributed the most to concession-related fire emissions from each island. Although fire emissions from concessions were higher in Kalimantan, emissions from Sumatra contributed 63% of concession-related smoke concentrations for the population-weighted region because fire sources were located closer to population centers. In order to protect regional public health, our results

Escherichia coli Protein Expression System for Acetylcholine Binding Proteins (AChBPs.

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Nikita Abraham

Full Text Available Nicotinic acetylcholine receptors (nAChR are ligand gated ion channels, identified as therapeutic targets for a range of human diseases. Drug design for nAChR related disorders is increasingly using structure-based approaches. Many of these structural insights for therapeutic lead development have been obtained from co-crystal structures of nAChR agonists and antagonists with the acetylcholine binding protein (AChBP. AChBP is a water soluble, structural and functional homolog of the extracellular, ligand-binding domain of nAChRs. Currently, AChBPs are recombinantly expressed in eukaryotic expression systems for structural and biophysical studies. Here, we report the establishment of an Escherichia coli (E. coli expression system that significantly reduces the cost and time of production compared to the existing expression systems. E. coli can efficiently express unglycosylated AChBP for crystallography and makes the expression of isotopically labelled forms feasible for NMR. We used a pHUE vector containing an N-terminal His-tagged ubiquitin fusion protein to facilitate AChBP expression in the soluble fractions, and thus avoid the need to recover protein from inclusion bodies. The purified protein yield obtained from the E. coli expression system is comparable to that obtained from existing AChBP expression systems. E. coli expressed AChBP bound nAChR agonists and antagonists with affinities matching those previously reported. Thus, the E. coli expression system significantly simplifies the expression and purification of functional AChBP for structural and biophysical studies.

Capacity Development and Strengthening for Energy Policy formulation and implementation of Sustainable Energy Projects in Indonesia CASINDO. Deliverable No. 38. Pro-poor Energy Strategy In North Sumatra

Energy Technology Data Exchange (ETDEWEB)

Soeharwinto [University of Sumatra Utara, Medan (Indonesia)

2011-12-15

The overall objective of the CASINDO programme is to establish a self-sustaining and self-developing structure at both the national and regional level to build and strengthen human capacity to enable the provinces of North Sumatra, Yogyakarta, Central Java, West Nusa Tenggara and Papua to formulate sound policies for renewable energy and energy efficiency and to develop and implement sustainable energy projects. A key component of the recent political reforms undertaken in Indonesia is the decentralization and regional autonomy that were implemented in 2001. This process has devolved almost all powers and responsibilities from the central government to the local government, including responsibilities for energy sector development. This means that regional governments are now responsible for formulating their energy policy and, consequently, must reform their institutional structure and strengthen their human capacity to be able to carry out this new responsibility. In Indonesia, people living in urban areas generally have access to efficient and modern energy supplies. However, the rural communities are generally less fortunate and continue to rely on traditional fuels of firewood, because the energy and electricity production system available to them are costly and inefficient. The aim of CASINDO's Technical Working Group V (TWG V) on Identification of Energy Needs and Assessment for Poor Communities was to establish energy-related needs and priorities of poor communities in selected locations in the Province of Central Java. The target location for Casindo TWG V activities was the village of Sruni, in the Boyolali district, because it is a district which produces a great amount of milk from dairy cows (greatest amount in Central Java); and secondly, because it does not receive any funds from other development programs, as well as from other institutions, while other subdistricts do. In order to identify actual energy needs successfully, the Participatory

Cyclopoid and calanoid copepod biodiversity in Indonesia

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Victor R. Alekseev

2013-10-01

Full Text Available Recent limnological investigations conducted on the large lakes of Indonesia provide valuable physical and ecological data for future environmental and developmental programmes, yet few studies have focused on zooplankton taxonomy. Here we describe Eucyclops troposperatus Alekseev et Yusoff n. sp. from a pond in Sumatra, and Mesocyclops jakartensis Alekseev n. sp. from a city pond in Jakarta, Java. In the pelagic zone of the lakes of Sulawesi we found only few copepod species. For the endemic cyclopoid Tropocyclops matanoensis Defaye, 2007, we propose a new subgenus, Defayeicyclops n. subg., and provide more data on the morphology as well as scanning electron microscopy and confocal laser scanning images of Tropocyclops (Defayeicyclops matanoensis. Two other cyclopoid species were possibly introduced to Sulawesi: Mesocyclops aequatorialis similis Van de Velde, 1984 from Africa and Thermocyclops crassus (Fischer, 1853 from Eurasia. A new subspecies, Phyllodiaptomus praedictus sulawesensis Alekseev et Vaillant n. ssp. (Calanoida, Diaptomidae, is described from the plankton of lake Tondano, North Sulawesi, Indonesia. The new subspecies resembles P. blanci (de Guerne et Richard, 1896 and P. wellekensae Dumont et Reddy, 1992. Phyllodiaptomus praedictus sulawesensis appears to be endemic to Sulawesi island. The form matanensis formerly treated as a subspecies of Eodiaptomus wolterecki Brehm, 1933 is here elevated to species rank, E. matanensis Brehm, 1933. A preliminary list of the copepod species found in Sulawesi and other large islands of Indonesia now includes more than 60 species. An updated key to the Southeast Asian species of the genus Eucyclops is provided.

Research mapping in North Sumatra based on Scopus

Science.gov (United States)

Nasution, M. K. M.; Sitepu, R.; Rosmayati; Bakti, D.; Hardi, S. M.

2018-02-01

Research is needed to improve the capacity of human resources to manage natural resources for human well-being. Research is done by institutions such as universities or research institutions, but the research picture related to human welfare interests is not easy to obtain. If research can be proven through scientific publications, scientific research publication databases can be used to view research behaviour. Research mapping in North Sumatra needs to be done to see the suitability of research conducted with development needs in North Sumatra, and as a presentation is the Universitas Sumatera Utara which shows that research conducted has 60% strength, especially in the exact sciences.

Discovery of potent and selective acetylcholinesterase (AChE) inhibitors: acacetin 7-O-methyl ether Mannich base derivatives synthesised from easy access natural product naringin.

Science.gov (United States)

Liu, Hao-Ran; Men, Xue; Gao, Xiao-Hui; Liu, Lin-Bo; Fan, Hao-Qun; Xia, Xin-Hua; Wang, Qiu-An

2018-03-01

Naringin, as a component universal existing in the peel of some fruits or medicinal plants, was usually selected as the material to synthesise bioactive derivates since it was easy to gain with low cost. In present investigation, eight new acacetin-7-O-methyl ether Mannich base derivatives (1-8) were synthesised from naringin. The bioactivity evaluation revealed that most of them exhibited moderate or potent acetylcholinesterase (AChE) inhibitory activity. Among them, compound 7 (IC 50 for AChE = 0.82 ± 0.08 μmol•L -1 , IC 50 for BuChE = 46.30 ± 3.26 μmol•L -1 ) showed a potent activity and high selectivity compared with the positive control Rivastigmine (IC 50 for AChE = 10.54 ± 0.86 μmol•L -1 , IC 50 for BuChE = 0.26 ± 0.08 μmol•L -1 ). The kinetic study suggested that compound 7 bind to AChE with mix-type inhibitory profile. Molecular docking study revealed that compound 7 could combine both catalytic active site (CAS) and peripheral active site (PAS) of AChE with four points (Trp84, Trp279, Tyr70 and Phe330), while it could bind with BuChE via only His 20.

Peripheral Inhibitor of AChE, Neostigmine, Prevents the Inflammatory Dependent Suppression of GnRH/LH Secretion during the Follicular Phase of the Estrous Cycle

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Andrzej P. Herman

2017-01-01

Full Text Available The study was designed to test the hypothesis that the inhibition of acetylcholinesterase (AChE activity at the periphery by Neostigmine (0.5 mg/animal will be sufficient to prevent inflammatory dependent suppression of the gonadotropin-releasing hormone (GnRH/luteinising hormone (LH secretion in ewes in the follicular phase of the estrous cycle, and this effect will be comparable with the systemic AChE inhibitor, Donepezil (2.5 mg/animal. An immune/inflammatory challenge was induced by peripheral administration of lipopolysaccharide (LPS; 400 ng/kg. Peripheral treatment with Donepezil and Neostigmine prevented the LPS-induced decrease (P<0.05 in LHβ gene expression in the anterior pituitary gland (AP and in LH release. Moreover, Donepezil completely abolished (P<0.05 the suppressory effect of inflammation on GnRH synthesis in the preoptic area, when pretreatment with Neostigmine reduced (P<0.05 the decrease in GnRH content in this hypothalamic structure. Moreover, administration of both AChE inhibitors diminished (P<0.05 the inhibitory effect of LPS treatment on the expression of GnRH receptor in the AP. Our study shows that inflammatory dependent changes in the GnRH/LH secretion may be eliminated or reduced by AChE inhibitors suppressing inflammatory reaction only at the periphery such as Neostigmine, without the need for interfering in the central nervous system.

Fiscal 1996 survey for the upgrading of the Asia/Pacific coal development. Survey of the coal infrastructure propagation in Indonesia; 1996 nendo Asia Taiheiyo sekitan kaihatsu kodoka chosa. Indonesia ni okeru sekitan infura seibi chosa

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-10-01

Phase 1 survey in fiscal 1996 was conducted based on `Agreement on the comprehensive survey of a coal transportation system in South Sumatra` concluded between NEDO and the Ministry of Mine and Energy in Indonesia. In the survey, conducted were collection of data on coal fields and site surveys, collection of data on inland transportation and site surveys, collection of data on harbors and site surveys, and worked out were a simplified database and a coal transportation plan by optimization of the coal chain system. The area for survey is the periphery of the Musi River of South Sumatra. The results of the simulation by LP models were as follows: When the coal of Bukit Asam coal mine is $25/t in price, only coal of 5500Kcal/kg is profitable, and when $27/t in price, coal of 4500Kcal/kg also becomes profitable. This shows that if the coal is of good quality, it can pay arriving at Suralaya, independent of the distance of transportation. 47 figs., 63 tabs.

Fluid-rock geochemical interaction for modelling calibration in geothermal exploration in Indonesia

Science.gov (United States)

Deon, Fiorenza; Barnhoorn, Auke; Lievens, Caroline; Ryannugroho, Riskiray; Imaro, Tulus; Bruhn, David; van der Meer, Freek; Hutami, Rizki; Sibarani, Besteba; Sule, Rachmat; Saptadij, Nenny; Hecker, Christoph; Appelt, Oona; Wilke, Franziska

2017-04-01

Indonesia with its large, but partially unexplored geothermal potential is one of the most interesting and suitable places in the world to conduct geothermal exploration research. This study focuses on geothermal exploration based on fluid-rock geochemistry/geomechanics and aims to compile an overview on geochemical data-rock properties from important geothermal fields in Indonesia. The research carried out in the field and in the laboratory is performed in the framework of the GEOCAP cooperation (Geothermal Capacity Building program Indonesia- the Netherlands). The application of petrology and geochemistry accounts to a better understanding of areas where operating power plants exist but also helps in the initial exploration stage of green areas. Because of their relevance and geological setting geothermal fields in Java, Sulawesi and the sedimentary basin of central Sumatra have been chosen as focus areas of this study. Operators, universities and governmental agencies will benefit from this approach as it will be applied also to new green-field terrains. By comparing the characteristic of the fluids, the alteration petrology and the rock geochemistry we also aim to contribute to compile an overview of the geochemistry of the important geothermal fields in Indonesia. At the same time the rock petrology and fluid geochemistry will be used as input data to model the reservoir fluid composition along with T-P parameters with the geochemical workbench PHREEQC. The field and laboratory data are mandatory for both the implementation and validation of the model results.

2Dbasin modelling of the hydrocarbon systems in the forearc basin of Sumatra; 2D-Beckenmodellierung des Kohlenwasserstoff-Systems im Forearc-Bereich von Sumatra

Energy Technology Data Exchange (ETDEWEB)

Stratmann, V.; Berglar, K.; Lutz, R.; Schloemer, S. [Bundesanstalt fuer Geowissenschaften und Rohstoffe, Hannover (Germany); Djajadihardja, Y.S. [Agency for the Assessment and Application of Technology, Jakarta (Indonesia)

2008-10-23

In the forearc basin of Sumatra, individual industrial drillings indicated the existence of hydrocarbons. The authors of the contribution under consideration report on an investigation of the hydrocarbon system within this forearc basin by means of a two-dimensional modelling of this basin. The structural development of the basins in the forearc area proceeded differently. Therefore, geophysical data for the investigation of the geological structures as well as geological/geochemical data were raised. The preliminary results of the two-dimensional modelling of the Simeulue basin northwest from Sumatra are presented.

Revealing the importance of linkers in K-series oxime reactivators for tabun-inhibited AChE using quantum chemical, docking and SMD studies.

Science.gov (United States)

Ghosh, Shibaji; Chandar, Nellore Bhanu; Jana, Kalyanashis; Ganguly, Bishwajit

2017-08-01

Inhibition of acetylcholinesterase (AChE) with organophosphorus compounds has a detrimental effect on human life. Oxime K203 seems to be one of the promising reactivators for tabun-inhibited AChE than (K027, K127, and K628). These reactivators differ only in the linker units between the two pyridinium rings. The conformational analyses performed with quantum chemical RHF/6-31G* level for K027, K127, K203 and K628 showed that the minimum energy conformers have different orientations of the active and peripheral pyridinium rings for these reactivator molecules. K203 with (-CH 2 -CH=CH-CH 2 -) linker unit possesses more open conformation compared to the other reactivators. Such orientation of K203 experiences favorable interaction with the surrounding residues of catalytic anionic site (CAS) and peripheral anionic site (PAS) of tabun-inhibited AChE. From the steered molecular dynamics simulations, it has been observed that the oxygen atom of the oxime group of K203 reactivator approaches nearest to the P-atom of the SUN203 (3.75 Å) at lower time scales (less than ~1000 ps) as compared to the other reactivators. K203 experiences less number of hydrophobic interaction with the PAS residues which is suggested to be an important factor for the efficient reactivation process. In addition, K203 crates large number of H-bonding with CAS residues SUN203, Phe295, Tyr337, Phe338 and His447. K203 barely changes its conformation during the SMD simulation process and hence the energy penalty to adopt any other conformation is minimal in this case as compared to the other reactivators. The molecular mechanics and Poisson-Boltzmann surface area binding energies obtained for the interaction of K203 inside the gorge of tabun inhibited AChE is substantially higher (-290.2 kcal/mol) than the corresponding K628 reactivator (-260.4 kcal/mol), which also possess unsaturated aromatic linker unit.

Revealing the importance of linkers in K-series oxime reactivators for tabun-inhibited AChE using quantum chemical, docking and SMD studies

Science.gov (United States)

Ghosh, Shibaji; Chandar, Nellore Bhanu; Jana, Kalyanashis; Ganguly, Bishwajit

2017-08-01

Inhibition of acetylcholinesterase (AChE) with organophosphorus compounds has a detrimental effect on human life. Oxime K203 seems to be one of the promising reactivators for tabun-inhibited AChE than (K027, K127, and K628). These reactivators differ only in the linker units between the two pyridinium rings. The conformational analyses performed with quantum chemical RHF/6-31G* level for K027, K127, K203 and K628 showed that the minimum energy conformers have different orientations of the active and peripheral pyridinium rings for these reactivator molecules. K203 with (-CH2-CH=CH-CH2-) linker unit possesses more open conformation compared to the other reactivators. Such orientation of K203 experiences favorable interaction with the surrounding residues of catalytic anionic site (CAS) and peripheral anionic site (PAS) of tabun-inhibited AChE. From the steered molecular dynamics simulations, it has been observed that the oxygen atom of the oxime group of K203 reactivator approaches nearest to the P-atom of the SUN203 (3.75 Å) at lower time scales (less than 1000 ps) as compared to the other reactivators. K203 experiences less number of hydrophobic interaction with the PAS residues which is suggested to be an important factor for the efficient reactivation process. In addition, K203 crates large number of H-bonding with CAS residues SUN203, Phe295, Tyr337, Phe338 and His447. K203 barely changes its conformation during the SMD simulation process and hence the energy penalty to adopt any other conformation is minimal in this case as compared to the other reactivators. The molecular mechanics and Poisson-Boltzmann surface area binding energies obtained for the interaction of K203 inside the gorge of tabun inhibited AChE is substantially higher (-290.2 kcal/mol) than the corresponding K628 reactivator (-260.4 kcal/mol), which also possess unsaturated aromatic linker unit.

Facile synthesis of new carbon-11 labeled conformationally restricted rivastigmine analogues as potential PET agents for imaging AChE and BChE enzymes

International Nuclear Information System (INIS)

Wang Min; Wang Jiquan; Gao Mingzhang; Zheng Qihuang

2008-01-01

Rivastigmine is a newer-generation inhibitor with a dual inhibitory action on both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes, and is used for the treatment of AChE- and BChE-related diseases such as brain Alzheimer's disease and cardiovascular disease. New carbon-11 labeled conformationally restricted rivastigmine analogues radiolabeled quaternary ammonium triflate salts, (3aR,9bS)-1-[ 11 C]methyl-1-methyl-6-(methylcarbamoyloxy)-2,3,3a,4,5, 9b-hexahy dro-1H-benzo[g]indolium triflate ([ 11 C]8) and (3aR,9bS)-1-[ 11 C]methyl-1-methyl-6-(heptylcarbamoyloxy)-2,3,3a,4,5, 9b-hexahy dro-1H-benzo[g]indolium triflate ([ 11 C]9), were designed and synthesized as potential positron emission tomography (PET) agents for imaging AChE and BChE enzymes. The appropriate precursors were labeled with [ 11 C]CH 3 OTf through N-[ 11 C]methylation, and the target tracers were isolated by solid-phase extraction (SPE) using a cation-exchange CM Sep-Pak cartridge in 40-50% radiochemical yields decay corrected to end of bombardment (EOB), 15-20 min overall synthesis time, and 148-222 GBq/μmol specific activity at EOB

Tsunami evacuation buildings and evacuation planning in Banda Aceh, Indonesia.

Science.gov (United States)

Yuzal, Hendri; Kim, Karl; Pant, Pradip; Yamashita, Eric

Indonesia, a country of more than 17,000 islands, is exposed to many hazards. A magnitude 9.1 earthquake struck off the coast of Sumatra, Indonesia, on December 26, 2004. It triggered a series of tsunami waves that spread across the Indian Ocean causing damage in 11 countries. Banda Aceh, the capital city of Aceh Province, was among the most damaged. More than 31,000 people were killed. At the time, there were no early warning systems nor evacuation buildings that could provide safe refuge for residents. Since then, four tsunami evacuation buildings (TEBs) have been constructed in the Meuraxa subdistrict of Banda Aceh. Based on analysis of evacuation routes and travel times, the capacity of existing TEBs is examined. Existing TEBs would not be able to shelter all of the at-risk population. In this study, additional buildings and locations for TEBs are proposed and residents are assigned to the closest TEBs. While TEBs may be part of a larger system of tsunami mitigation efforts, other strategies and approaches need to be considered. In addition to TEBs, robust detection, warning and alert systems, land use planning, training, exercises, and other preparedness strategies are essential to tsunami risk reduction.

MODIS data used to study 2002 fires in Kalimantan, Indonesia

Science.gov (United States)

Fuller, Douglas O.

Smoke and haze blanketed western Indonesia during August and September 2002, signaling the arrival of another El Niño event in Southeast Asia. Although not as severe as the 1997-1998 El Niño event, the 2002 El Niño produced drought conditions in western Indonesia that favored extensive biomass burning in lowland areas of Borneo, Sumatra, and Sulawesi, three of the largest islands that form part of the vast Indonesian archipelago. Data derived from the Moderate Resolution Imaging Spectrometer (MODIS) on board the NASA Terra satellite showed that most of the burning during 2002 occurred in central and western Kalimantan (Indonesian Borneo), where forests are being cleared to make way for industrial oil palm and pulp plantations.Comparison of fire data from several different satellite sensors also reveals that fires detected in Kalimantan during 1997 appeared more numerous (Figure 1) and burned over a longer period (Figure 2) than fires that burned in late 2002 (see discussion below). This result is consistent with recent El Niño observations that characterize the current event as moderate relative to the 1997-1998 event (see http://www.cpc.ncep.noaa.gov/ products/analysis_monitoring/enso_advisory/).

Repeated administration of alpha7 nicotinic acetylcholine receptor (nAChR) agonists, but not positive allosteric modulators, increases alpha7 nAChR levels in the brain

DEFF Research Database (Denmark)

Christensen, Ditte Z; Mikkelsen, Jens D; Hansen, Henrik H

2010-01-01

AChR binding sites in several brain regions, particularly in the prefrontal cortex. The alpha7 nAChR agonists SSR180711 and PNU-282987 also increase [(125)I]-BTX binding, suggesting that this is a general consequence of alpha7 nAChR agonism. Interestingly, the alpha7 nAChR positive allosteric modulators PNU......The alpha7 nicotinic acetylcholine receptor (nAChR) is an important target for treatment of cognitive deficits in schizophrenia and Alzheimer's disease. However, the receptor desensitizes rapidly in vitro, which has led to concern regarding its applicability as a clinically relevant drug target....... Here we investigate the effects of repeated agonism on alpha7 nAChR receptor levels and responsiveness in vivo in rats. Using [(125)I]-alpha-bungarotoxin (BTX) autoradiography we show that acute or repeated administration with the selective alpha7 nAChR agonist A-582941 increases the number of alpha7 n...

The prospect of coal supplier for future coal: major expansion of energy supply/demand in Indonesia

Energy Technology Data Exchange (ETDEWEB)

Tirtosoekotjo, S. [Ministry of Mines and Energy (Indonesia)

2000-07-01

Since the mid 1980s Indonesia's coal industry has shown a high development growth both in production and coal sales. The majority of coal producers are located in Sumatra and Kalimantan islands and the majority of domestic coal consumers are located in Java islands, while the major Indonesian coal exporters are Asia-Pacific countries (80%). In the future (up to 2003) there will be more domestic and export potential demand which will increase at an average of 2-3 million tons per annum (15%) and 5-7 million tons per annum (11%) respectively. 4 refs., 2 figs., 7 tabs.

AChR-specific immunosuppressive therapy of myasthenia gravis.

Science.gov (United States)

Luo, Jie; Lindstrom, Jon

2015-10-15

Myasthenia gravis (MG) is an organ-specific autoimmune disease characterized by muscle fatigability. In most cases, it is mediated by autoantibodies targeting muscle nicotinic acetylcholine receptors (AChRs) at the neuromuscular junction. Experimental autoimmune myasthenia gravis (EAMG) is an animal model for MG, which is usually induced by immunization with AChR purified from fish electric organ. Pathological autoantibodies to AChRs are directed at the extracellular surface, especially the main immunogenic region (MIR). Current treatments for MG can help many but not all patients. Antigen-specific immunosuppressive therapy for MG that specifically suppresses the autoimmune response without affecting the entire immune system and avoids side effects of general immunosuppression is currently unavailable. Early attempts at antigen-specific immunosuppression for EAMG using AChR extracellular domain sequences that form epitopes for pathological autoantibodies risked provoking autoimmunity rather than suppressing it. We discovered a novel approach to specific immunosuppression of EAMG with a therapeutic vaccine consisting of bacterially-expressed human AChR cytoplasmic domains, which has the potential to specifically suppress MG without danger of causing exacerbation. This approach prevents development of chronic EAMG when initiated immediately after the acute phase of EAMG, and rapidly reverses established chronic EAMG when started during the chronic phase of EAMG. Successfully treated rats exhibited long-term resistance to re-induction of EAMG. In this review we also discuss the current understanding of the mechanisms by which the therapy works. Vaccination with AChR cytoplasmic domains in adjuvant is promising as a safe, antigen-specific, potent, effective, rapidly acting, and long lasting approach to therapy of MG. Copyright © 2015 Elsevier Inc. All rights reserved.

A Green Method for Synthesis of 7H-thiazolo[3,2-b][1,2, 4]-triazin-7-one Derivatives as AChE Inhibitors

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Liu Sijie

2015-01-01

Full Text Available The authors study an efficient and green approach for the synthesis of 7H-thiazolo [3, 2-b][1,2,4]triazin-7-one derivatives as AChE inhibitors. The 7H-thiazolo[3,2-b][1,2,4]triazin-7-ones were designed by molecular docking, and readily prepared via a one-pot reaction in morpholine hydrosulfate ([Hnhm]HSO4 lonic liquid as the catalyst and solvent. The study of AChE inhibitory activity was carried out through using the Ellman colorimetric assay. The 7H-thiazolo[3,2-b][1,2,4]triazin-7-ones had been successfully synthesized by green catalyst. Most of the target compounds exhibited more than 50% inhibition at 10μM.

EVALUATION OF NATURAL ENEMIES IN CONTROLLING OF THE BANANA WEEVIL BORER Cosmopolites sordidus Germar IN WEST SUMATRA

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Ahsol Hasyim

2016-10-01

Full Text Available The banana weevil, Cosmopolites sordidus Germar, is an important pest of highland banana and plantain in Africa, but it exists in low densities in presumed area of origin in Southeast Asia such as in Indonesia. This suggests a possible existence of effective co-evolved natural enemies in the origin area of Indonesia, especially West Sumatra. The objectives of this study were: (1 to evaluate banana weevil pest status at selected sites in West Sumatra, (2 to survey parasitoids and predators, and (3 to determine the control potential of the most important natural enemies. Surveys were undertaken in March 2002-August 2003 in five locations in West Sumatra, i.e., Bukittinggi, Sitiung, Pariaman, Pasaman, and Batusangkar. Five farms per site were selected randomly among all farms that contained banana stands of > 0.5 ha. Sampling for banana weevil adults and damage, and for predators was done throughout small banana stands and within a 20 m x 40 m (0.08 ha subplot on larger farms. Field-collected larvae were taken to the laboratory and reared on corm pieces (3 cm x 3 cm x 3 cm until pupation. Larvae were collected from pseudostem as well as corm residues. To estimate the abundance of non-social predators, i.e., those other than ants, 10 residues each on each farm were examined from plants that had been harvested 1-4 weeks, 5-8 weeks or 9 or more weeks before our visit to the site. Samples of the different morphospecies were saved in alcohol for later identification. The result showed that the banana weevil incidence was found to be low,  0.6-1.7 adults per trap. Plant damage indices were below 2.2%. We collected and reared 24,360 eggs and 3118 larvae, but no parasitism was detected. Phorids (Megaselia sp. and drosophilids were recovered from larval rearings, but most likely were scavengers. A complex of predators was detected, the most important of which was the histerid beetles,  Plaesius javanus Erichson. In laboratory tests, adults and larvae

A new species of Nepenthes (Nepenthaceae from Sumatra

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Pitra Akhriadi

2003-12-01

Full Text Available AKHRIADI, PITRA, HERNAWATI & TAMIN, RUSJDI. 2004. A new species of Nepenthes (Nepenthaceae from Sumatra. Reinwardtia 12 (2: 141 – 144. ─ A New Species of Nepenthes rigidifolia is described.

A report from YMC Sumatra field campaign

Science.gov (United States)

Yoneyama, K.; Yokoi, S.; Mori, S.; Nasuno, T.; Yamanaka, M. D.; Yasunaga, K.; Haryoko, U.; Nurhayati, N.; Syamsudin, F.

2017-12-01

Years of the Maritime Continent (YMC) is a two-year international field campaign from July 2017 through the early 2020. It aims at enhancing our knowledge of weather-climate systems over the Maritime Continent and its relation to higher latitudes through observations and numerical modeling. YMC field observations consist of several Intensive Observation Periods (IOPs) and routine basis long-term observations done by local agencies. One of IOPs is a joint effort done by Japanese and Indonesian research groups and we call it YMC-Sumatra, which studies precipitation mechanism along the west coast of Sumatra Island (Bengkulu city) especially focusing on a relationship between diurnal cycle convection and large-scale disturbances such as the Madden-Julian Oscillation (MJO). Observations will be carried out from November 16, 2017 through January 15, 2018. Since it is known that diurnally developed convection over the coast propagates offshore in the night time, we will deploy a ship off the coast in addition to the land-based site in Bengkulu meteorological station. From both sides, we conduct scanning weather radars, 3-hourly radiosonde soundings, and continuous surface meteorological measurements. Ocean surface is also intensively measured by 3-hourly CTD, ADCP, turbulent sensor, and so on from the ship. In addition, two types of forecast run (global 7-/14-km mesh for 14-/30-day forecast) using NICAM will be performed. Since this campaign in Sumatra is being done during the AGU meeting, a preliminary live report will be provided, so that scientific results as well as logistics information can be used for further IOPs.

Insect nicotinic acetylcholine receptors (nAChRs): Important amino ...

African Journals Online (AJOL)

STORAGESEVER

2008-12-29

Dec 29, 2008 ... nAChRs within the insect central nervous system has led to the development of insecticides targeting .... binding protein (AChBP), a homopentameric structural and functional homolog of ..... of the honey bee, Apis mellifera.

A "new" Nitidulid Beetle from Sumatra

NARCIS (Netherlands)

Jong, de C.

1953-01-01

Some time ago I was asked to identify a fossil coleopteron which had been found in the drill cuttings of an oil well in the Southern part of Sumatra. As the fossil is only a few millimetres long it may be mentioned as an amazing fact that so small an object has been found during rather rough work

Can hydroxylamine be a more potent nucleophile for the reactivation of tabun-inhibited AChE than prototype oxime drugs? An answer derived from quantum chemical and steered molecular dynamics studies.

Science.gov (United States)

Lo, Rabindranath; Ganguly, Bishwajit

2014-07-29

Organophosphorus nerve agents are highly toxic compounds which strongly inhibit acetylcholinesterase (AChE) in the blood and in the central nervous system (CNS). Tabun is one of the highly toxic organophosphorus (OP) compounds and is resistant to many oxime drugs formulated for the reactivation of AChE. The reactivation mechanism of tabun-conjugated AChE with various drugs has been examined with density functional theory and ab initio quantum chemical calculations. The presence of a lone-pair located on the amidic group resists the nucleophilic attack at the phosphorus center of the tabun-conjugated AChE. We have shown that the newly designed drug candidate N-(pyridin-2-yl)hydroxylamine, at the MP2/6-31+G*//M05-2X/6-31G* level in the aqueous phase with the polarizable continuum solvation model (PCM), is more effective in reactivating the tabun-conjugated AChE than typical oxime drugs. The rate determining activation barrier with N-(pyridin-2-yl)hydroxylamine was found to be ∼1.7 kcal mol(-1), which is 7.2 kcal mol(-1) lower than the charged oxime trimedoxime (one of the most efficient reactivators in tabun poisonings). The greater nucleophilicity index (ω(-)) and higher CHelpG charge of pyridinylhydroxylamine compared to TMB4 support this observation. Furthermore, we have also examined the reactivation process of tabun-inhibited AChE with some other bis-quaternary oxime drug candidates such as methoxime (MMB4) and obidoxime. The docking analysis suggests that charged bis-quaternary pyridinium oximes have greater binding affinity inside the active-site gorge of AChE compared to the neutral pyridinylhydroxylamine. The peripheral ligand attached to the neutral pyridinylhydroxylamine enhanced the binding with the aromatic residues in the active-site gorge of AChE through effective π-π interactions. Steered molecular dynamics (SMD) simulations have also been performed with the charged oxime (TMB4) and the neutral hydroxylamine. From protein-drug interaction

Distribution of peatlands in Indonesia

Energy Technology Data Exchange (ETDEWEB)

Rieley, J. [Dept. of Life Science, Nottingham (United Kingdom); Page, S.E. [Leicester Univ. (United Kingdom). Dept. of Zoology; Setiadi, B. [Agency for the Assesment and Application of Technology, Jakarta (Indonesia)

1996-12-31

Indonesia contains between 160 and 270 000 km{sup 2} of peatland, mostly in the sub-coastal lowlands of Irian Jaya, Kalimantan and Sumatra; depth varies from 0.5 to more than 10 metres. Present day peat started to accumulate in response to very wet climatic conditions after the end of the last glacial period on waterlogged substrates of low nutrient status and oxygen deficiency. Coastal and basin peatlands were preceded by mangrove swamp; Yiigh peat (peat at a slightly higher elevation) was probably initiated in freshwater swamp. Dates of origin range from 800 to almost 5 000 years B.P. for the former and over 9 000 years B.P. for the latter. Lowland tropical peat is relatively homogeneous, consisting of trunks, branches and roots of trees; it is mainly fibric with low mineral content. Peat domes are ombrogenous with a water table close to or above the surface for most of the year. Lowland peat swamps support a zonation of forest types. The marginal, mixed swamp forest is dominated by high canopy trees whilst the interior `pole` forest consists of lower, smaller diameter trees. Indonesian peat swamp forests are an important reservoir of biodiversity; they contain several commercial tree species and provide a range of non-timber forest products. Almost 20 % of the peat swamp forests of Indonesia have been developed for agriculture and settlement. In their natural condition, however, they act as important water catchment and control systems, stabilize the landscape against erosion and maintain water quality for downstream riverine, estuarine and coastal fisheries. (orig.) (19 refs.)

Financial Profitability and Sensitivity Analysis of Palm Oil Plantation in Indonesia

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Tereza Svatoňová

2015-01-01

Full Text Available Oil palm cultivation in Indonesia is increasing. This study investigates the financial and economic aspects of establishing an oil palm plantation using data collected in 2014. The financial case study is undertaken from the perspective of company in North Sumatra, Indonesia. A spreadsheet model was used to develop and calculate the net present value (NPV, return of investment (ROI, internal rate of return (IRR and payback period (PP. Sensitivity analysis of the NPV to the default discount rate (10% was included. A 8,000 ha plantation over 25 years was estimated to result in a positive NPV of USD 10,670 with a ROI 73.50% and an IRR at 14.83% and payback period of 6.75 years. Establishing an oil palm plantation seems to be very profitable investment on the basis of the assumptions made. System is tested on sensitivity in different capital and recurrent costs and in selling price of raw material, while change in selling price of FFB is more sensitive to NPV than change in investment and recurrent costs Discount rate is also one of the factors affecting NPV and system is tested between 5–15% change in discount rate.

Acetylcholinesterase Regulates Skeletal In Ovo Development of Chicken Limbs by ACh-Dependent and -Independent Mechanisms.

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Janine Spieker

Full Text Available Formation of the vertebrate limb presents an excellent model to analyze a non-neuronal cholinergic system (NNCS. Here, we first analyzed the expression of acetylcholinesterase (AChE by IHC and of choline acetyltransferase (ChAT by ISH in developing embryonic chicken limbs (stages HH17-37. AChE outlined formation of bones, being strongest at their distal tips, and later also marked areas of cell death. At onset, AChE and ChAT were elevated in two organizing centers of the limb anlage, the apical ectodermal ridge (AER and zone of polarizing activity (ZPA, respectively. Thereby ChAT was expressed shortly after AChE, thus strongly supporting a leading role of AChE in limb formation. Then, we conducted loss-of-function studies via unilateral implantation of beads into chicken limb anlagen, which were soaked in cholinergic components. After varying periods, the formation of cartilage matrix and of mineralizing bones was followed by Alcian blue (AB and Alizarin red (AR stainings, respectively. Both acetylcholine (ACh- and ChAT-soaked beads accelerated bone formation in ovo. Notably, inhibition of AChE by BW284c51, or by the monoclonal antibody MAB304 delayed cartilage formation. Since bead inhibition of BChE was mostly ineffective, an ACh-independent action during BW284c51 and MAB304 inhibition was indicated, which possibly could be due to an enzymatic side activity of AChE. In conclusion, skeletogenesis in chick is regulated by an ACh-dependent cholinergic system, but to some extent also by an ACh-independent aspect of the AChE protein.

The prevalence and risk factors of stunting among primary school children in North Sumatera, Indonesia

Science.gov (United States)

Lestari, S.; Fujiati, I. I.; Keumalasari, D.; Daulay, M.

2018-03-01

Stunting in primary school-aged children is a kind of health and nutrition problem in Indonesia which has an impact on the human quality resources degradation. This research aimed to determine the stunting prevalence and the risk factors associated with stunting in primary school children in North Sumatra Province. This research is an analysis of cross-sectional approach. The total sampleis 400 children aged 8-13 years old were in the study from the Medan city and Langkat regency in July - October 2017. Data collected by using questionnaire and anthropometric assessment. Stunting (<-2 SD of height-for-age Z-score) were defined by using the World Health Organization reference 2007. Chi-square analysis and logistic regression were used toassess the association between risk factors and stunting. The prevalence of stunting in primary school children was 38.87%. The factors associated with stunting school children were theeducation of mother (OR=1.53), income (OR=2.27), work of mother (OR=1.39), energy intake (OR=2.66) and protein intake (OR=2.02). The dominant factor that influences stunting in school children was energy intake. The conclusion of this study is stunting prevalence in school children in NorthSumatra higher.

Economic corridor of industrial development in Indonesia

Science.gov (United States)

Berawi, M. A.; Miraj, P.; Sidqi, H.

2017-12-01

Indonesia as an archipelago country categorize its regional development into six corridors from Sumatra, Java, Kalimantan, Sulawesi, Bali-Nusa Tenggara and Papua-Maluku. Currently, industrial development becomes one of the highest contributing factors to the national economic growth. However, each region in the nation experience inequality of development mainly related to the infrastructure sector. Thus, the research aims to develop a sustainable economic corridor by considering the characteristics and its potential. The research uses a qualitative approach through a desk study, benchmarking and in-depth interview. Location Quotient is used for the method of the analysis tool. The results show each characteristic of every corridor in the country. Sumatera as national plantation and processing industry corridor, Java as cyber technology innovation and services center, Kalimantan as national energy reserves and processing, Sulawesi as national aquaculture and processing industry, Bali - Nusa Tenggara as national eco-tourism center, and Papua - Maluku as national ore mining and processing.

Dual Inhibition of AChE and BChE with the C-5 Substituted Derivative of Meldrum’s Acid: Synthesis, Structure Elucidation, and Molecular Docking Studies

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Haroon Mehfooz

2017-07-01

Full Text Available Alzheimer’s disease (AD lies in the category of those diseases which are still posing challenges to medicinal chemists, and the search for super-effective drugs for the treatment of AD is a work in progress. The inhibition of cholinesterase is considered a viable strategy to enhance the level of acetylcholine in the brain. The C-5 substituted derivative of Meldrum’s acid was synthesized and screened against acetylcholinesterase (AChE and butyrylcholinesterase (BChE enzyme inhibition activity. The simple and unique structure of synthesized derivative 3 was found to be good for the dual inhibition of both enzymes (AChE and BChE. 2,2-Dimethyl-5-(([2-(trifluoromethyl phenyl]aminomethylidene-1,3-dioxane-4,6-dione (3 showed significant inhibition against AChE, with an IC50 value of 1.13 ± 0.03 µ M (Standard Neostigmine 22.2 ± 3.2 µM, and moderate inhibition against BChE, with an IC50 value of 2.12 ± 1.22 µM (Standard Neostigmine 49.6 ± 6.11 µM. The structural insights reveal that compound 3 possesses intriguing reactive groups, which can potentially evoke the non-covalent interactions and possibly assist by binding in the active site of the target protein. Docking simulations revealed that the compound 3 showed binding inside the active site gorges of both AChE and BChE. An excellent agreement was obtained, as the best docked poses showed important binding features mostly based on interactions due to oxygen atoms and the aromatic moieties of the compound. The docking computations coupled with the experimental findings ascertained that the compound 3 can serve as a scaffold for the dual inhibitors of the human acetylcholine esterases.

MRI of hyperacute stroke in the AChA territory

Energy Technology Data Exchange (ETDEWEB)

Hamoir, Xavier L.; Grandin, Cecile B.; Cosnard, Guy; Duprez, Thierry [Department of Medical Imaging, Cliniques Universitaires Saint-Luc, Universite Catholique de Louvain, Avenue Hippocrate 10, 1200, Brussels (Belgium); Peeters, Andre [Department of Neurology, Cliniques Universitaires Saint-Luc, Universite Catholique de Louvain, Avenue Hippocrate 10, 1200, Brussels (Belgium); Robert, Annie [Department of Epidemiology, Biostatistics Unit of the Public Health School, Cliniques Universitaires Saint-Luc, Universite Catholique de Louvain, Avenue Hippocrate 10, 1200, Brussels (Belgium)

2004-03-01

The purpose of our study was to derive from the anatomical literature an easy-to-use map of the brain areas supplied by the anterior choroidal artery (AChA) and to assess the correspondence between damage within the putative AChA areas and clinical symptoms. A thorough review of the literature led to the recognition of 16 anatomical areas which could be delineated on routine diffusion-weighted MR images. A database of 138 consecutive ischemic stroke patients examined with MRI less than 6 h after symptoms onset was thereafter processed in a retrospective way. Patients presenting with at least one damaged AChA area were selected so as to assess the prevalence of AChA infarction and the clinical correlates of the condition. Fifteen patients (11%) had at least one damaged AChA area. Only two of them had ''pure'' AChA-restricted infarction. Contralateral hemiparesis and contralateral hemianesthesia were best predicted by lesions within the tail of the caudate nucleus with a sensitivity of 87% and 83%, respectively. Homonymous hemianopsia best correlated with lesions within the posterior limb of the internal capsule and within the retrolenticular part of the internal capsule, with a sensitivity of 100% and a specificity of 70% for both areas. We concluded that the clinical-radiological correlations did not match the neurophysiological standards, thereby highlighting the limitation of this study, which involved a cohort of acute stroke patients recruited from clinical practice and investigated the clinical impact of these brain lesions, even when documented with the most sensitive imaging modality. (orig.)

MRI of hyperacute stroke in the AChA territory

International Nuclear Information System (INIS)

Hamoir, Xavier L.; Grandin, Cecile B.; Cosnard, Guy; Duprez, Thierry; Peeters, Andre; Robert, Annie

2004-01-01

The purpose of our study was to derive from the anatomical literature an easy-to-use map of the brain areas supplied by the anterior choroidal artery (AChA) and to assess the correspondence between damage within the putative AChA areas and clinical symptoms. A thorough review of the literature led to the recognition of 16 anatomical areas which could be delineated on routine diffusion-weighted MR images. A database of 138 consecutive ischemic stroke patients examined with MRI less than 6 h after symptoms onset was thereafter processed in a retrospective way. Patients presenting with at least one damaged AChA area were selected so as to assess the prevalence of AChA infarction and the clinical correlates of the condition. Fifteen patients (11%) had at least one damaged AChA area. Only two of them had ''pure'' AChA-restricted infarction. Contralateral hemiparesis and contralateral hemianesthesia were best predicted by lesions within the tail of the caudate nucleus with a sensitivity of 87% and 83%, respectively. Homonymous hemianopsia best correlated with lesions within the posterior limb of the internal capsule and within the retrolenticular part of the internal capsule, with a sensitivity of 100% and a specificity of 70% for both areas. We concluded that the clinical-radiological correlations did not match the neurophysiological standards, thereby highlighting the limitation of this study, which involved a cohort of acute stroke patients recruited from clinical practice and investigated the clinical impact of these brain lesions, even when documented with the most sensitive imaging modality. (orig.)

Paleomagnetic tests for tectonic reconstructions of the Late Jurassic-Early Cretaceous Woyla Group, Sumatra

Science.gov (United States)

Advokaat, Eldert; Bongers, Mayke; van Hinsbergen, Douwe; Rudyawan, Alfend; Marshal, Edo

2017-04-01

SE Asia consists of multiple continental blocks, volcanic arcs and suture zones representing remnants of closing ocean basins. The core of this mainland is called Sundaland, and was formed by accretion of continental and arc fragments during the Paleozoic and Mesozoic. The former positions of these blocks are still uncertain but reconstructions based on tectonostratigraphic, palaeobiogeographic, geological and palaeomagnetic studies indicate the continental terranes separated from the eastern margin of Gondwana. During the mid-Cretaceous, more continental and arc fragments accreted to Sundaland, including the intra-oceanic Woyla Arc now exposed on Sumatra. These continental fragments were derived from Australia, but the former position of the Woyla Arc is unconstrained. Interpretations on the former position of the Woyla Arc fall in two end-member groups. The first group interprets the Woyla Arc to be separated from West Sumatra by a small back-arc basin. This back arc basin opened in the Late Jurassic, and closed mid-Cretaceous, when the Woyla Arc collided with West Sumatra. The other group interprets the Woyla Arc to be derived from Gondwana, at a position close to the northern margin of Greater India in the Late Jurassic. Subsequently the Woyla Arc moved northwards and collided with West Sumatra in the mid-Cretaceous. Since these scenarios predict very different plate kinematic evolutions for the Neotethyan realm, we here aim to place paleomagnetic constraints on paleolatitudinal evolution of the Woyla Arc. The Woyla Arc consists mainly of basaltic to andesitic volcanics and dykes, and volcaniclastic shales and sandstones. Associated limestones with volcanic debris are interpreted as fringing reefs. This assemblage is interpreted as remnants of an Early Cretaceous intra-oceanic arc. West Sumatra exposes granites, surrounded by quartz sandstones, shales and volcanic tuffs. These sediments are in part metamorphosed. This assemblage is interpreted as a Jurassic

Fishing Farmers or Farming Fishers? Fishing Typology of Inland Small-Scale Fishing Households and Fisheries Management in Singkarak Lake, West Sumatra, Indonesia

Science.gov (United States)

Yuerlita; Perret, Sylvain Roger; Shivakoti, Ganesh P.

2013-07-01

Technical and socio-economic characteristics are known to determine different types of fishers and their livelihood strategies. Faced with declining fish and water resources, small-scale fisheries engage into transformations in livelihood and fishing practices. The paper is an attempt to understand these changes and their socio-economic patterns, in the case of Singkarak Lake in West Sumatra, Indonesia. Based upon the hypothesis that riparian communities have diverse, complex yet structured and dynamic livelihood systems, the paper's main objective is to study, document and model the actual diversity in livelihood, practices and performance of inland small-scale fisheries along the Singkarak Lake, to picture how households are adapted to the situation, and propose an updated, workable model (typology) of those for policy. Principal component analysis and cluster analysis were used to develop a typology of fishing households. The results show that small-scale fishers can be classified into different types characterized by distinct livelihood strategies. Three household types are identified, namely "farming fishers" households (type I, 30 %), "fishing farmers" households (type II, 30 %), and "mainly fishers" households (type III, 40 %). There are significant differences among these groups in the number of boats owned, annual fishing income, agriculture income and farming experience. Type I consists of farming fishers, well equipped, with high fishing costs and income, yet with the lowest return on fishing assets. They are also landowners with farming income, showing the lowest return on land capital. Type II includes poor fishing farmers, landowners with higher farming income; they show the highest return on land asset. They have less fishing equipment, costs and income. Type III (mainly fishers) consists of poorer, younger fishers, with highest return on fishing assets and on fishing costs. They have little land, low farming income, and diversified livelihood

NUMERICAL SIMULATION OF UJONG SEUDEUN LAND SEPARATION CAUSED BY THE 2004 INDIAN OCEAN TSUNAMI, ACEH-INDONESIA

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Musa Al'ala

2015-07-01

Full Text Available The Aceh province in Indonesia, located around the Sumatra subduction area, was one of the worst hit areas with respect to damage from the impact of the 2004 Indian Ocean tsunami. A 9.15 Mw earthquake triggered the tsunami. One of the impacts was the disconnection of several areas from their mainland, thus creating new small islands. This happened around Ujong Seudeun village in Aceh Jaya District. Prior to the tsunami, the village had approximately 500 residents. However, after the tsunami, the area was severely eroded and a small strait had been inserted between the village and the Sumatra Island mainland. This study investigates the magnitude of the tsunami wave forces that separated the area to yield a newly deserted small island. This study was conducted by numerical simulations and by coupling the COMCOT (Cornell Multi-grid Coupled Tsunami Model and Delft3D models. These tools have specific advantages, namely, COMCOT’s linear modeling is based on a series of earthquake mechanisms and Delft3D uses non-linear morphological dynamic modeling. Their software includes the explicit leapfrog finite difference scheme (COMCOT and the non-linear shallow water equation (Delft3D. Bathymetry data fromnewly formed coastline and the small island’s shape were digitized using 2005 Quickbird Images. Results from this research reveal the estimated tsunami wave heights and forces that disconnected the small island of Ujong Seuden from the Sumatra Island mainland. These results can be used to further develop the COMCOT model to incorporate sediment modules.

TREES AND REGENERATION IN RUBBER AGROFORESTS AND OTHER FOREST-DERIVED VEGETATION IN JAMBI (SUMATRA, INDONESIA

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Hesti L. Tata

2008-06-01

Full Text Available The rubber  agroforests  (RAF  of Indonesia provide  a dynamic interface  between natural  processes  of forest  regeneration and  human’s management   targeting  the harvesting  of latex  with  minimum investment  of time  and financial  resources.  The composition  and species richness  of higher  plants  across an intensification gradient from forest to monocultures of tree crops have been investigated  in six land use types (viz. secondary forest, RAF, rubber monoculture, oil palm plantation, cassava field and Imperata grassland  in Bungo,  Jambi  Province,  Indonesia.  We emphasize  comparison of four different  strata  (understory, seedling,  sapling  and tree of vegetation  between forest and RAF,  with  specific interest  in plant  dependence  on ectomycorrhiza fungi. Species richness  and species accumulation curves for seedling  and sapling  stages were similar  between forest and RAF,  but in the tree stratum  (trees > 10 cm dbh selective thinning by farmers was evident in a reduction  of species diversity and an increase in the proportion of trees with edible parts. Very few trees dependent on ectomycorrhiza fungi were encountered  in the RAF. However, the relative distribution of early and late successional species as evident from the wood density distribution showed no difference between RAF and forest.

Land use changes and plantation crop development in selected provinces in Sumatra and Kalimantan

Science.gov (United States)

Tarigan, S. D.

2018-05-01

Most institutions stated that biofuel will not qualify the standard of GHG emission reduction if it was produced in the plantation associated with the forest conversion. Therefore, knowing previous land use before the development of plantation is very important. In Indonesia, plantation development occurs mainly in Sumatra and Kalimantan. A number of studies had been published showing historical LUCC before plantation development. Objective of this study was to review various studies on LUCC carried out in four selected provinces, namely West Kalimantan, Central Kalimantan, East Kalimantan, and Riau. The analysis and comparison was based on the different source of historical data including online spatial data sources and various studies published in various journals. Each data source of LUCC shows significant variation on the amount of plantation developed directly from forest and other land use types. But, our review showed that the plantation areas associated with the forest cover changes far less than those claimed by several international journals. But, the debate concerning which plantation developments indirectly contributed to LUCC and which are directly will probably continue until the information on the land ownership and history of plantation development is available publicly.

Comparative functional expression of nAChR subtypes in rodent DRG neurons.

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Smith, Nathan J; Hone, Arik J; Memon, Tosifa; Bossi, Simon; Smith, Thomas E; McIntosh, J Michael; Olivera, Baldomero M; Teichert, Russell W

2013-01-01

We investigated the functional expression of nicotinic acetylcholine receptors (nAChRs) in heterogeneous populations of dissociated rat and mouse lumbar dorsal root ganglion (DRG) neurons by calcium imaging. By this experimental approach, it is possible to investigate the functional expression of multiple receptor and ion-channel subtypes across more than 100 neuronal and glial cells simultaneously. Based on nAChR expression, DRG neurons could be divided into four subclasses: (1) neurons that express predominantly α3β4 and α6β4 nAChRs; (2) neurons that express predominantly α7 nAChRs; (3) neurons that express a combination of α3β4/α6β4 and α7 nAChRs; and (4) neurons that do not express nAChRs. In this comparative study, the same four neuronal subclasses were observed in mouse and rat DRG. However, the expression frequency differed between species: substantially more rat DRG neurons were in the first three subclasses than mouse DRG neurons, at all developmental time points tested in our study. Approximately 70-80% of rat DRG neurons expressed functional nAChRs, in contrast to only ~15-30% of mouse DRG neurons. Our study also demonstrated functional coupling between nAChRs, voltage-gated calcium channels, and mitochondrial Ca(2) (+) transport in discrete subsets of DRG neurons. In contrast to the expression of nAChRs in DRG neurons, we demonstrated that a subset of non-neuronal DRG cells expressed muscarinic acetylcholine receptors and not nAChRs. The general approach to comparative cellular neurobiology outlined in this paper has the potential to better integrate molecular and systems neuroscience by uncovering the spectrum of neuronal subclasses present in a given cell population and the functionally integrated signaling components expressed in each subclass.

Study on the Highly Sensitive AChE Electrode Based on Multiwalled Carbon Nanotubes

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Shuping Zhang

2014-01-01

Full Text Available Using chitosan (CS as carrier, the method named layer-by-layer (LBL self-assembly modification to modify the glassy carbon electrode (GCE with multiwalled carbon nanotubes (MWNTs and acetylcholine esterase (AChE was proposed to prepare the acetylcholine esterase electrode with high sensitivity and stability. The modified electrode was used to detect pesticide of aldicarb, and the enzyme inhibition rate of the electrode showed good linearity with pesticide concentrations in the range of 10−10 g·L−1 to 10−3 g·L−1. The detection limit was 10−11 g·L−1. The modified electrode was also used to detect the actual sample, and the recovery rate range was from 97.72% to 107.15%, which could meet the rapid testing need of the aldicarb residue. After being stored in the phosphate buffer solution (PBS in 4°C for 30 days, the modified electrode showed good stability with the response current that was 80% of the original current.

STRUCTURE OF THE LITHOSPHERE AND SEISMOTECTONIC DEFORMATIONS IN CONTACT ZONE OF LITHOSPHERIC PLATES IN THE SUMATRA ISLAND REGION

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O. A. Kuchay

2015-01-01

Full Text Available The inversion seismic tomography algorithm (ITS was used to calculate 3D seismic anomalies models for velocities of P- and S-waves in the zone of the Sunda arc, Indonesia. In the area under study, strong earthquakes (M>4.8 are clustered in the zone of high P-wave velocities. Earthquake hypocenters are located in zones of both high and low velocity anomalies of S-waves. The giant Sumatra earthquake (December 26, 2004, Mw=9.0 ruptured the greatest fault length of any recorded earthquake, and the rupture started in the area wherein the sign of P-wave velo­city anomalies is abruptly changed. We calculated seismotectonic deformations (STD from data on mechanisms of 2227 earthquakes recorded from 1977 to 2013, and our calculations show that the STD component, that controls vertical extension of rocks, is most stable through all the depth levels. In the marginal regions at the western and eastern sides of the Sunda arc, the crustal areas (depths from 0 to 35 km are subject to deformations which sign is opposite to that of deformations in the central part. Besides, at depths from 70 to 150 km beneath the Sumatra earthquake epicentre area, the zone is subject to deformations which sign is opposite to that of deformations in the studied part of the Sunda arc. For earthquakes that may occur in the crust in the Sunda arc in the contact zone of the plates, maximum magnitudes depend on the direction of pressure imposed by the actively subducting plate, which is an additional criteria for determining the limit magnitude for the region under study. 

Horizontal Displacement Vector Analysis in Ujong Muloh GPS Station (UMLH) Sumatra Island on March 27 – April 25, 2012

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Pamungkas, S. S.; Koesuma, S.; Legowo, Budi

2018-03-01

Sumatra Island is an area that has high tectonic activities. This is because the island of Sumatra is located in two major plates of the world, the Indo-Australian plate and the Eurasia plate. The subduction zone causes Sumatra to deform from time to time. The deformation of Sumatra Island can be observed by continuous recording coordinates using the GPS Station. Continous-GPS (C-GPS) in Sumatra Island is named Sumatran GPS Array (SuGAr), one of them named UMLH. The UMLH GPS station used to observe the displacement in the Aceh City of Sumatra Island, is located in Ujung Muloh. The changes of GPS coordinate recording data can represent the deformation pattern that occurred in Sumatra. On April 11, 2012, according to USGS data, there had been an earthquake in the city of Aceh about 8.6 at coordinates of 2.433°N, 93.072°E. The purpose of this research is to analyze the horizontal displacement due to the occurrence of the earthquake. Data processing is carried out using software GAMIT/GLOBK. The magnitude of the displacement of Sumatra Island before the earthquake, during the earthquake, and after the quake on component X were respectively: 0.04 mm/day, 56.63 mm/day, and 8.28 mm/day; while on component Y were respectively: 0.03 mm/day, 23.78 mm/day, and 1.22 mm/day. The direction of displacement was 253.8° towards Southwest with the assumption that 0° was in the North.

Phenomenon of Women Marginalization in Poor Family in Pakpak Community (A Case Study in Pegagan Julu Village, Sumbul Subdistrict, Dairi Regency - North Sumatra - Indonesia)

OpenAIRE

Hadriana Marhaeni Munthe

2017-01-01

This article is taken from the study of marginalization cases experienced by Pakpak women of rural poor families. The study was conducted in Pegagan village of Sumbul Subdistrict, Dairi, North Sumatra province. The marginalization phenomenon is shown in some aspects; restrictions on women's access to formal education, tendency of dropping out of school, having no inheritance rights and no role in the decision making of custom. Related to this phenomenon, the research question of this study is...

THE GAP ANALYSIS OF DEVELOPMENT BETWEEN REGENCY OR CITY IN THE PROVINCE OF NORTH SUMATRA FOR THE PERIOD 2004-2008

OpenAIRE

Muhammad Yusuf

2013-01-01

One of the main functions of the government of North Sumatra Province is how to reduce the gap between the district / city in the province of North Sumatra. A regional disparity is the ratio of real per capita income among regions with per capita real income of the province. This study aims to analyze the development gap among districts / cities in North Sumatra. In addition, this study also analyzes the Klasen typology at each district / city in North Sumatra. The data’s that used in this st...

Monitoring the UPS and Downs of Sumatra and Java with D-Insar Time-Series

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Chaussard, E.; Amelung, F.

2010-12-01

We performed, for the first time, a global D-InSAR survey of the Indonesian islands of Sumatra and Java to define locations where deformation is occurring. The goals of this study are 1) to create an inventory of actively deforming volcanic centers and 2) monitor all types of ground motion. This work provides ground deformation data for previously unmonitored areas and can assist the Indonesian authorities to improve hazards assessment. The D-InSAR survey covers an area of about 500 000 km2 and 3000 km long on the islands of Sumatra, Java and Bali. We used ALOS data from 45 tracks and more than 1500 granules obtained from the Alaska Satellite Facility (ASF) through the US Government Research Consortium (USGRC). We completed more than 1000 interferograms spanning a period from the end of 2006 to the beginning of 2009. L-band SAR images enable deformation mapping at global scales even in highly vegetated areas where C-band signal experiences loss of coherence. To identify locations where ground deformations are occurring, we used multiple SAR acquisitions of the same area and performed time series analysis using the Small BAseline Subset (SBAS) method. Interferograms with a maximum spatial baseline of 3000 m were phase-unwrapped and subsequently inverted for the phase with respect to the first acquisition. Temporal coherence of each pixel is computed on the set of interferograms in order to select only pixels with high temporal coherence. The compiled InSAR velocity map reveals the background level of activity of the 84 volcanic centers constituting the Sumatra, Java and Bali volcanic arcs. We identified possible uplift at 6 volcanic centers: Agung (Bali), Lamongan (Java), Lawu (Java), Slamet (Java), Kerinci (Sumatra) and Sinabung (Sumatra). Moreover, we identified subsidence in 5 major cities and 1 coastal area. Subsidence rates range from 6 cm/yr in Medan, the largest city of Sumatra, to more than 15 cm/yr in Jakarta. These major subsidence areas are probably due

EXPERIENCE OF BARRIERS TO HYPERTENSION MANAGEMENT IN MINANGKABAU ETHNIC GROUP IN PAYAKUMBUH INDONESIA: A PHENOMENOLOGICAL STUDY

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Vera Kurnia

2018-05-01

Full Text Available Background: Understanding barriers to hypertension managements remains important to reduce the hypertension rate in community. Minangkabau is one of the ethnic groups in West Sumatra Indonesia that has a high proportion of people with hypertension although its management has been implemented. Objective: This study aims to explore the experiences of barriers to hypertension management in Minangkabau ethnic group in Payakumbuh, Indonesia. Methods: This was a phenomenological study with twelve respondents selected using purposive sampling. Data were collected using in-depth interview. Colaizzi’s content analysis method was used for data analysis. Results: Five themes were emerged from the data, namely: (i lack of self-motivation in the management of hypertension, (ii disobedience in the management of hypertension, (iii culture pattern of food intake, (iv lack of social support, and (v excessive stress and anxiety. Conclusions: The barriers to hypertension management in Minangkabau ethnic group are closely related to its culture both in lifestyle and in food intake of the family members and the community. Nurses are expected toalways give health education about hypertension and finding the way to control it.

Organic carbon sequestration under selected land use in Padang city, West Sumatra, Indonesia

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Yulnafatmawita; Yasin, S.

2018-03-01

Organic carbon is a potential element to build biomass as well as emitting CO2 to the atmosphere and promotes global warming. This research was aimed to calculate the sequestered Carbon (C) within a 1-m soil depth under selected land use from 6 different sites in Padang city, Indonesia. Disturbed and undisturbed soil samples were taken from several horizons until 100 cm depth at each location. Soil parameters observed were organic carbon (OC), bulk density (BD), and soil texture. The result showed that soil OC content tended to decrease by the depth at all land use types, except under rice field in Kurao-Nanggalo which extremely increased at >65 cm soil depth with the highest carbon stock. The soil organic carbon sequestration from the highest to the lowest according to land use and the location is in the following order mix garden- Kayu Aro > mix garden- Aie Pacah > Rangeland- Parak Laweh >seasonal farming- Teluk Sirih > rice field- Kampuang Jua.

On a new Flying Squirrel from Deli, Sumatra

NARCIS (Netherlands)

Jentink, F.A.

1890-01-01

Sciuropterus setosus, collected by Horner in the neighborhood of Padang (Sumatra) and described by Temminck in the »Fauna japonica”, seems to be such an extremely rare animal, that the type-specimen — an adult female — is the only individual hitherto observed by collectors and naturalists. Mr.

ACh-induced hyperpolarization and decreased resistance in mammalian type II vestibular hair cells.

Science.gov (United States)

Poppi, Lauren A; Tabatabaee, Hessam; Drury, Hannah R; Jobling, Phillip; Callister, Robert J; Migliaccio, Americo A; Jordan, Paivi M; Holt, Joseph C; Rabbitt, Richard D; Lim, Rebecca; Brichta, Alan M

2018-01-01

In the mammalian vestibular periphery, electrical activation of the efferent vestibular system (EVS) has two effects on afferent activity: 1) it increases background afferent discharge and 2) decreases afferent sensitivity to rotational stimuli. Although the cellular mechanisms underlying these two contrasting afferent responses remain obscure, we postulated that the reduction in afferent sensitivity was attributed, in part, to the activation of α9- containing nicotinic acetylcholine (ACh) receptors (α9*nAChRs) and small-conductance potassium channels (SK) in vestibular type II hair cells, as demonstrated in the peripheral vestibular system of other vertebrates. To test this hypothesis, we examined the effects of the predominant EVS neurotransmitter ACh on vestibular type II hair cells from wild-type (wt) and α9-subunit nAChR knockout (α9 -/- ) mice. Immunostaining for choline acetyltransferase revealed there were no obvious gross morphological differences in the peripheral EVS innervation among any of these strains. ACh application onto wt type II hair cells, at resting potentials, produced a fast inward current followed by a slower outward current, resulting in membrane hyperpolarization and decreased membrane resistance. Hyperpolarization and decreased resistance were due to gating of SK channels. Consistent with activation of α9*nAChRs and SK channels, these ACh-sensitive currents were antagonized by the α9*nAChR blocker strychnine and SK blockers apamin and tamapin. Type II hair cells from α9 -/- mice, however, failed to respond to ACh at all. These results confirm the critical importance of α9nAChRs in efferent modulation of mammalian type II vestibular hair cells. Application of exogenous ACh reduces electrical impedance, thereby decreasing type II hair cell sensitivity. NEW & NOTEWORTHY Expression of α9 nicotinic subunit was crucial for fast cholinergic modulation of mammalian vestibular type II hair cells. These findings show a multifaceted

The local knowledge of food plants used by Karo ethnic in Semangat Gunung Village, North Sumatra, Indonesia

Science.gov (United States)

Nisyawati, Aini, R. N.; Silalahi, M.; Purba, E. C.; Avifah, N.

2017-07-01

Research on the local knowledge of food plants used by Karo ethnic in the Semangat Gunung Village, North Sumatra has been done. The aim of this study is to reveal plant species that used by the people of Karo ethnic as food. We used the ethnobotanical approach which included open-ended, semi-structural interview, and exploration method. One eldervillage, 2 traditional healers, and 30 respondents have been selected as sources of information. Descriptive statistics have been used to analyze the gathered data. A number of 109 species which belong to 83 genus and 45 families known to be used as food sources by Karo people. Four families have the highest number of food plant species, which are Solanaceae (8 species), Poaceae (7 species), Fabaceae (6 species), and Zingiberaceae (6 species). All of those families are found in the village, both wild and Cultivated. Solanaceae is used as source of fruits, vegetables, and spices. Poaceae is used as the source of the staple food, alternative food sources, snacks, spices, and traditional foods. Fabaceae is used as source of vegetables and traditional foods. Zingiberaceae is used as source of spices.

KAJIAN DAERAH RAWAN GELOMBANG TINGGI DI PERAIRAN INDONESIA

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Roni Kurniawan

2014-08-01

generally wider than the Australia monsoon period. In the transitional period between monsoons, most of the Indonesian territorial waters are not high waves prone areas. High waves prone areas in the transitional period between monsoons are generally narrower and it were in the Indonesian waters, which became part of the South China Sea, Pacific Ocean and Indian Ocean, particularly southern part of Java to Bengkulu. Although the correlation is not significant, El-Nino led to an increasing wave height in the eastern waters of Indonesia, especially north of the equator and La-Nina led to an increasing wave height in the Indonesian waters around the Indian Ocean, especially in the southern part of Java, while the negative IODM caused increasing wave height in the northern equator of western part of Sumatra waters.

Mini review : Pengolahan kerupuk “Rambak” kulit di Indonesia

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Dedes Amertaningtyas

2011-12-01

Full Text Available ABSTRACT: Hide a waste product of animal slaughter house is still can be utilized as food in the form of cracker. Cattle, buffalo, rabbit, chicken shank and fish skin can be used of raw materials for cracker production. This process include hide selection, washing, immersing, liming, deliming, boiling, cutting, immersing in sauce, drying and frying. In Indonesia, the skin cracker industriesare consentralised in certain area of west, central and east java provinces where Sumatra skin cracker are popular knows as “ kerupuk jangek”. Although skin cracker have a high protein content, however its quality are low comparedto other meat processed products. The most dominant amino acid in this product is glycine. Some important issues such as it is not recommended for people suffering uric acid, addition of harmfull additives i.e. formalin and borax, containg chrome which originated from hide prosessing industry and unreligion system of slaughtering (is not halal. Key words: waste product, skin animal, rambak cracker.

Cost estimation of sumatra electricity expansion planning with nuclear option

International Nuclear Information System (INIS)

Edwaren Liun

2008-01-01

The objective of the study is to obtain the cost analysis on optimum solution of Sumatra electricity system using WASP-IV Program. Considering the economic aspect, nuclear power plant (NPP) is feasible in the future. From the geographical aspect Sumatra is prospecting for NPP site, especially the east coastal area due to the absence of hydro power potential and geothermal field. The use of petroleum as fuel in large scale power plants is not feasible. Beside causing high cost for electricity sector, it is also an important fuel for any other sectors such as transportation, electrification of isolated areas. Gas fuelled power plants is still feasible for next several decades in limited capacity. The study presents three scenarios, i.e. Low Scenario, Base Scenario and High Scenario applying discount rate of 8%, 10% and 12% respectively. Cost estimation for Sumatra System Expansion Planning is 57 465 million US$ on the Base Scenario - discount rate 8%, 59 349 million US$ on the Base Scenario - discount rate 10%, and 57 796 million US$ on the Base Scenario - discount rate 12%. The objective function is 15 172 US$ on the Base Scenario - discount rate 8%, 12 663 million US$ on the Base Scenario - discount rate 10%, and 11 017 million US$ on the Base Scenario - discount rate 12%. (author)

[Experience of Handicap International in providing humanitarian relief in region near Aceh, Indonesia from March 1 to 27, 2005].

Science.gov (United States)

Gillet, Y

2005-01-01

This report describes the experience of the author in March 2005 during the relief efforts deployed in the region near Aceh, Indonesia (North Sumatra) by Handicap International, one of the 400 NGO that provided humanitarian aid following the tsunami disaster that struck Southeast Asia on December 26, 2004. Working in Banda Aceh and Meulaboh, the author was confronted with the extent of the devastation both in terms of property damage and human suffering. Clinical cases were often severe and rarely encountered in industrialized countries. The tsunami worsened the already poor sanitary conditions: rundown care facilities, poorly trained health care personnel, tropical disease, poor hygiene, and AVP.

PREVALENSI PENYAKIT HIPERTENSI PENDUDUK DI INDONESIA DAN FAKTOR YANG BERISIKO

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Sarwanto Sarwanto

2012-11-01

Full Text Available Background: The analysis of hypertension prevalence for Indonesia citizen aging of 15 years old and over, and its risk factors has been conducted. Data of National Health Basic Survey (Riskesdas 2007 and National Health Survey (Susenas 2007 data were used. Methods: Variables analyzed were: 1 Social Economics and individual characteristics (age, sex, marital status, education, settlement area, social economic groups, 2 Risk behavior (smoking habit, fruits and vegetables consumption, 3 Body Mass Index (BMI group, and 4 Mental disordered. Analysis emphasized on descriptionof hypertension prevalence by social economics, individual characteristics, risk behavior factors, BMI groups and mental disordered. The correlation of hypertension toward behavior factors, BMI groups, and mental disordered groups were done in order to determine the relationship between them using logistics regression technique. It was also to find out the most dominant factor. Results: showed that 34.9% Indonesia citizen suffered from hypertension (by measuring individual blood pressure. People in Java-Bali has the highest prevalence (35.9% of hypertension while the lowest was in Sumatra (32.9%. Hypertension prevalence (by interview respondents diagnosed the health professional only 7.4%. Multiple logistics regression analysis showed that heavy smoker, obese, and heavy mental disorder has correlation significantly (p = 0.000 toward hypertension. The most dominant factor increasing hypertension risked was obese. Keywords: hypertension, risk factors, National Health Basic Survey (Riskesdas 2007

A program to develop the domestic natural gas industry in Indonesia: Case history of two World Bank projects

International Nuclear Information System (INIS)

Klass, D.L.; Khwaja, S.

1991-01-01

Indonesia depends heavily on revenues from the export of LNG and oil, the availability of which appears to be decreasing. It is therefore making a strong effort to accelerate development of a domestic natural gas industry. A high priority has been given to the conversion of power plants and city gas systems, including local industries and commercial facilities, from liquid fuels to natural gas. This will release more oil for export, help to meet the objectives of Repelita V, and provide substantial environmental benefits. The World Bank recently provided loans to the Indonesian Government for two projects that are aimed at substituting natural gas for oil and manufactured gas in domestic markets. One project involves expansion of the gas distribution systems of Indonesia's natural gas utility (PGN) in three cities: Jakarta and Bogor in Java, and Medan in Sumatra. The project also includes training programs for PGN staff and an energy pricing policy study to be carried out by Indonesia's Ministry of Mines and Energy. The second project involves expansion of the supply of natural gas for Surabaya and twelve other towns in its vicinity in East Java, and further expansion of Medan's supply system. Technical assistance will be provided to enhance the skills ofPGN and the Ministry of Mines and Energy, and a Gas Technology Unit similar to the Institute of Gas Technology will be established at Indonesia's Research and Development Center for Oil and Gas (LEMIGAS) in Jakarta. 14 refs., 3 figs., 11 tabs

Morfologi dan kekerabatan antara Leopoldamys siporanus (Thomas, 1985 dan L. sabanus (Thomas, 1987 (Muridae asal Kepulauan Mentawai, Sumatra, Kalimantan dan Jawa

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Ibnu Maryanto

1999-06-01

Full Text Available Jawa, Anamba, and Leopoldamys siporanus from Siberut and Pagai-Mentawai Islands was analyzed using discriminant analysis. The analysis showed that the morphological shape of Sumatran L. sabanus was an intermediate between Jawa and Kalimantan populations. The population of L. sabanus from Anamba Island was predicted to be closed to the intermediate from between Kalimantan and Sumatra. Specimens of L. siporanus from Siberut and Pagai indicated that their morphology was closer to that of L. sabarus from Kalimantan than it was from Sumatra or Jawa. In Sumatra L. sabarus has three subspecies which are distributed in northern side of West Sumatra (L.s. tapanulius, southern side of West Sumatra (L.s. ululans and Mount Kerinci at Sumatra (L.s. vociferans. Furthermore, specimens examined in this study were collected from Leuser and Bengkulu where they are located at the corner of tapanulius and ululans type locality, and they were predicted as one population. This finding raises the possibility that the Sumatrans has one shape of L. sabanus, but this argument should be confirmed from prototype specimens of ululans, vociferans, and tapanulius.

Indische bergcultuurondernemingen voornamelijk in Zuid-Sumatra : gegevens en beschouwingen

NARCIS (Netherlands)

Hoedt, T.G.E.

1930-01-01

Highland crops was here used of tropical perennial crops (cinchona, coffee, rubber, tea), cultivated mainly in mountain districts. These crops were grown on estates, owned by western companies and managed by European staff. The organization of the highland plantation industry in Java and Sumatra,

Taeniasis/cysticercosis in Papua (Irian Jaya), Indonesia.

Science.gov (United States)

Margono, Sri S; Wandra, Toni; Swasono, Meutia F; Murni, Sri; Craig, Philip S; Ito, Akira

2006-01-01

Reports showed that an important parasitic zoonotic disease caused by Taenia solium, Taenia saginata and Taenia asiatica is found endemic in several areas of Indonesia including Papua, Bali and North Sumatra. At present it is known that the highest prevalence of taeniasis/cysticercosis in Indonesia, caused by T. solium is among the indigenous communities in Papua (formerly Irian Jaya). In the early 1970s, 8-9% of stool samples from the Enarotali hospital, Paniai District (Irian Jaya) were found positive with Taenia eggs. The samples were from members of the Ekari (Kapauku) ethnic group. Stool samples from the Moni ethnic group, living east of surrounding lakes, were egg negative. Cysticerci of T. solium were discovered in pigs. During the years 1973-1976 cases of burns increased and were ultimately found to be primarily associated with epileptic seizures induced by neurocysticercosis cases. Among 257 cases of burns, 88 cases (62.8%) were suffering from epileptic seizures before or during hospitalization. In the year 1981 T. solium seropositive persons were mostly (16%) found in the endemic Obano village. In 1997 the parasite was discovered in Jayawijaya District, which is located approximately 250 km east of Paniai District. During 1991-1995, a local health center in Assologaima, Jayawijaya District reported 1120 new cases with burns and a further 293 new cases of epileptic seizures among 15,939 inhabitants. The histopathologic appearance and mitochondrial DNA analysis found the cysts to be similar to those of T. solium from other regions of the world. Sensitive and specific serological diagnostic methods were used and improved. Cysticerci were detected in dogs, as well as in pigs. A coproantigen test for detection of adult tapeworms in patients was carried out. Medical treatment with praziquantel for taeniasis and albendazole for cysticercosis (with prednisone and sodium phenytoin treatment in cases with neurocysticercosis) was undertaken. Lifestyle, religion, and

Correlation of the oldest Toba Tuff to sediments in the central Indian Ocean Basin

Digital Repository Service at National Institute of Oceanography (India)

Pattan, J.N.; ShyamPrasad, M.; Babu, E.V.S.S.K.

of the late Pleistocene eruption of Toba, north Sumatra; Nature 276 574–577. Nishimura S, Abe E, Yokoyama T, Wirasantosa S, Dharma A and Danau 1977 Toba – The outline of lake Toba, North Sumatra, Indonesia; Paleolimnology of Lake Biwa and the Japanese...

Capacity Development and Strengthening for Energy Policy formulation and implementation of Sustainable Energy Projects in Indonesia CASINDO. Deliverable No. 22. Energy Profile of Yogyakarta Province 2007. Regional CASINDO Team of Yogyakarta

Energy Technology Data Exchange (ETDEWEB)

Al Hasibi, R.A. [Universitas Muhammadiyah Yogyakarta PUSPER-UMY, Yogyakarta (Indonesia)

2011-09-15

The overall objective of the CASINDO programme is to establish a self-sustaining and self-developing structure at both the national and regional level to build and strengthen human capacity to enable the provinces of North Sumatra, Yogyakarta, Central Java, West Nusa Tenggara and Papua to formulate sound policies for renewable energy and energy efficiency and to develop and implement sustainable energy projects. This report gives an overview of the province Yogyakarta, Indonesia, focusing on the energy balance in 2007.

Capacity Development and Strengthening for Energy Policy formulation and implementation of Sustainable Energy Projects in Indonesia CASINDO. Deliverable No. 23. Energy Profile of Yogyakarta Province 2008. Regional CASINDO Team of Yogyakarta

Energy Technology Data Exchange (ETDEWEB)

Al Hasibi, R.A. [Universitas Muhammadiyah Yogyakarta PUSPER-UMY, Yogyakarta (Indonesia)

2011-09-15

The overall objective of the CASINDO programme is to establish a self-sustaining and self-developing structure at both the national and regional level to build and strengthen human capacity to enable the provinces of North Sumatra, Yogyakarta, Central Java, West Nusa Tenggara and Papua to formulate sound policies for renewable energy and energy efficiency and to develop and implement sustainable energy projects. This report gives an overview of the province Yogyakarta, Indonesia, focusing on the energy balance in 2008.

Capacity Development and Strengthening for Energy Policy formulation and implementation of Sustainable Energy Projects in Indonesia CASINDO. Deliverable No. 21. Energy Profile of Yogyakarta Province 2006. Regional CASINDO Team of Yogyakarta

Energy Technology Data Exchange (ETDEWEB)

NONE

2011-07-15

The overall objective of the CASINDO programme is to establish a self-sustaining and self-developing structure at both the national and regional level to build and strengthen human capacity to enable the provinces of North Sumatra, Yogyakarta, Central Java, West Nusa Tenggara and Papua to formulate sound policies for renewable energy and energy efficiency and to develop and implement sustainable energy projects. This report gives an overview of the province Yogyakarta, Indonesia, focusing on the energy balance in 2006.

Nutritional Potential of Selected Insect Species Reared on the Island of Sumatra.

Science.gov (United States)

Adámková, Anna; Mlček, Jiří; Kouřimská, Lenka; Borkovcová, Marie; Bušina, Tomáš; Adámek, Martin; Bednářová, Martina; Krajsa, Jan

2017-05-12

Inhabitants of the Indonesian island of Sumatra are faced with the problem of insufficient food supplies and the consequent risk of undernourishment and health issues. Edible insects as a traditional and readily available food source could be part of the solution. The nutritional value of insects depends on many factors, e.g., species, developmental stage, sex, diet, and climatic conditions. However, edible insects bred in Sumatra for human consumption have never before been assessed with regard to their nutritional value. Our study involved analyses of crude protein, chitin, fat and selected fatty acid contents of giant mealworm larvae ( Zophobas morio ), larvae of the common mealworm ( Tenebrio molitor) and nymphs of the field cricket ( Gryllus assimilis ). Crude protein content in the samples ranged from 46% to 56%. Highest (35%) and lowest (31%) amounts of fat were recorded in giant mealworm larvae and larvae of the common mealworm, respectively. Chitin amounts ranged from 6% to 13%. Based on these values, which are comparable to those known from other food insects reared in different regions of the world, the edible species bred in Sumatra could become food sources with a potential to help stave off hunger and undernourishment.

Phylogeny of kemenyan (Styrax sp.) from North Sumatra based on morphological characters

Science.gov (United States)

Susilowati, A.; Kholibrina, C. R.; Rachmat, H. H.; Munthe, M. A.

2018-02-01

Kemenyan is the most famous local tree species from North Sumatra. Kemenyan is known as rosin producer that very valuable for pharmacheutical, cosmetic, food preservatives and vernis. Based on its history, there were only two species of kemenyan those were kemenyan durame and toba, but in its the natural distribution we also found others species showing different characteristics with previously known ones. The objectives of this research were:The objectives of this research were: (1). To determine the morphological diversity of kemenyan in North Sumatra and (2). To determine phylogeny clustering based on the morphological characters. Data was collected from direct observation and morphological characterization, based on purposive sampling technique to those samples trees atPakpak Bharat, North Sumatra. Morphological characters were examined using descriptive analysis, phenotypic variability using standard deviation, and cluster analysis. The result showed that there was a difference between 4 species kemenyen (batak, minyak, durame and toba) according to 75 observed characters including flower, fruits, leaf, stem, bark, crown type, wood and the resin. Analysis and both quantitative and qualitative characters kemenyan clustered into two groups. In which, kemenyan toba separated with other clusters.

New constraints on the magnitude of the 4 January 1907 tsunami earthquake off Sumatra, Indonesia, and its Indian Ocean-wide tsunami

Science.gov (United States)

Martin, S. S.; Li, L.; Okal, E.; Kanamori, H.; Morin, J.; Sieh, K.; Switzer, A.

2017-12-01

On 4 January 1907, an earthquake and tsunami occurred off the west coast of Sumatra, Indonesia, causing at least 2,188 fatalities. The earthquake was given an instrumental surface-wave magnitude (MS) in the range of 7.5 to 8.0 at periods of ≈40s. The tsunami it triggered was destructive on the islands of Nias and Simeulue; on the latter, this gave rise to the legend of the S'mong. This tsunami appears in records in India, Pakistan, Sri Lanka, and as far as the island of La Réunion. In relation to published seismic magnitudes for the earthquake, the tsunami was anomalously large, qualifying it as a "tsunami earthquake." Relocations using reported arrival times suggest an epicentral location near the trench. However, unusually for a tsunami earthquake the reported macroseismic intensities were higher than expected on Nias (6-7 EMS). We present a new study of this event based on macroseismic and tsunami observations culled from published literature and colonial press reports, as well as existing and newly acquired digitized or print seismograms. This multidisciplinary combination of macroseismic and seismological data with tsunami modelling has yielded new insights into this poorly understood but scientifically and societally important tsunami earthquake in the Indian Ocean. With these new data, we discriminated two large earthquakes within an hour of each other with clear differences in seismological character. The first, we interpret to be a tsunami earthquake with low levels of shaking (3-4 EMS). For this event, we estimate a seismic moment (M0) between 0.8 and 1.2 x1021 Nm (≈MW 7.9 to 8.0) based on digitized Wiechert records at Göttingen in the frequency band 6-8 mHz. These records document a regular growth of moment with period and suggest possibly larger values of M0 at even longer periods. The second earthquake caused damage on Nias (6-7 EMS). We estimate MS 6 ¾ - 7 for the second event based on seismograms from Manila, Mizusawa, and Osaka. We also

Prototype Tsunami Evacuation Park in Padang, West Sumatra, Indonesia

Science.gov (United States)

Tucker, B. E.; Cedillos, V.; Deierlein, G.; Di Mauro, M.; Kornberg, K.

2012-12-01

Padang, Indonesia, a city of some 900,000 people, half of whom live close to the coast and within a five-meter elevation above sea level, has one of the highest tsunami risks in the world due to its close offshore thrust-fault seismic hazard, flat terrain and dense population. There is a high probability that a tsunami will strike the shores of Padang, flooding half of the area of the city, within the next 30 years. If that tsunami occurred today, it is estimated that several hundred thousand people would die, as they could not reach safe ground in the ~30 minute interval between the earthquake's occurrence and the tsunami's arrival. Padang's needs have been amply demonstrated: after earthquakes in 2007, 2009, 2011 and 2012, citizens, thinking that those earthquakes might cause a tsunami, tried to evacuate in cars and motorbikes, which created traffic jams, and most could not reach safe ground in 30 minutes. Since 2008, GeoHazards International (GHI) and Stanford University have studied a range of options for improving this situation, including ways to accelerate evacuation to high ground with pedestrian bridges and widened roads, and means of "vertical" evacuation in multi-story buildings, mosques, pedestrian overpasses, and Tsunami Evacuation Parks (TEPs), which are man-made hills with recreation facilities on top. TEPs proved most practical and cost-effective for Padang, given the available budget, technology and time. The Earth Observatory Singapore (EOS) developed an agent-based model that simulates pedestrian and vehicular evacuation to assess tsunami risk and risk reduction interventions in Southeast Asia. EOS applied this model to analyze the effectiveness in Padang of TEPs over other tsunami risk management approaches in terms of evacuation times and the number of people saved. The model shows that only ~24,000 people (20% of the total population) in the northern part of Padang can reach safe ground within 30 minutes, if people evacuate using cars and

[Women's approach to childhood toothache, abdominal ache and earache].

Science.gov (United States)

Efe, Emine; Öncel, Selma; Yilmaz, Mualla

2012-01-01

This study was conducted to determine women's about attitudes child's teeth, abdomen and ear ache. Those who had lived in Antalya that 6 number primary health care center between March-May 2004 were enrolled in the study. As data collecting tools. A questionnaire prepared by the authors. This study was determined that 29.2 % of the mothers carried out mixture who had prepared at home to child's abdomen and foot base; 30.3 % were to put breast milk childs' ear; 38.9 % were placed aspirin, salt and salts of lemon to childs' teeth ache. The majority of the women make a wrong practices child that teeth, abdomen and ear ache. This traditional practice effecting factors were the women's educational status and age. The results of the study that education about child care, common health problems and incorrect applications shoud be given to women by nurse.

Determinan Kejadian Cedera pada Kelompok Pekerja Usia Produktif di Indonesia

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Lusianawaty Tana

2015-11-01

Full Text Available AbstractInternational Labor Organization (ILO in 2008 estimated that 14 % of the 2.34 million people died as a result of work-related accidents. In Indonesia, work-related accidents data are still limited and only focus on the formal sector. The research purpose was to identify the determinant of the injury in Indonesia productive age (15-64 years old workers.This study was a further analysis of National Health Research (Riskesdas data in 2013. The data were analyzed by complex sample with significancelevel 0.05 and 95% confidence intervals. The workers who met the study criterias were 405,984 persons. The determinant of injury was age, gender, hypertension, region area, visual and hearing impairment, education, diabetes mellitus, marrital status, body mass index, occupation, economical status, subdistrict area (OR adjusted 1.1-2.17 p≤0.009. The injury of the 15-24 years old group was 2.17 times higher than55-64 years old group, males were injured 1.8 times higher than females, workers who had hypertension were 1.6 times than normotension. Workers stayed in Eastern Indonesia Region was injured 1.5 times higher than in Sumatra Region, and workers with hearing impairment in both ears were injured 1.5 times higher than normal hearing. The main determinant of injury in productive age workers was age, gender, hypertension, and hearing impairment. Efforts to prevent injury were required, especially foryoung workers.Keywords : workers, injury, productive age, Indonesia, Riskesdas 2013 AbstrakInternational Labor Organization (ILO memperkirakan 14% dari 2,34 juta orang meninggal dunia akibat kecelakaan kerja (2008. Di Indonesia, data terkait kecelakaan yang berhubungan dengan pekerjaan masih terbatas dan hanya fokus pada pekerja sektor formal. Penelitian ini bertujuan menentukan determinan kejadian cedera pada pekerja usia produktif (15-64 tahun di Indonesia, menggunakan data Riset Kesehatan Dasar (Riskesdas Tahun 2013. Data dianalisis dengan kompleks

Richtlijnen voor een ontwikkelingsplan voor de Oostkust van Sumatra

NARCIS (Netherlands)

Waal, van de R.

1959-01-01

Suggestions were made to improve the agricultural situation resulting from the Second World war. The former estate agriculture on the East Coast of Sumatra, established in 1865 by westerners in a sparsely populated and isolated area, occupied 1,000,000 ha in 1940 mainly under tobacco, rubber, oil

Rediscovery of Curcuma sumatrana (Zingiberaceae) endemic to West Sumatra

NARCIS (Netherlands)

Ardiyani, M.; Anggara, A.; Leong-Škorničková, J.

2011-01-01

A recent exploration of Sumatra resulted in the re-collection of Curcuma sumatrana, an endemic Zingiberaceae species of unclear identity that was first described by Miquel nearly 150 years ago. The history of this species is discussed, a detailed description with a colour plate is provided and a

Future fire emissions associated with projected land use change in Indonesia

Science.gov (United States)

Marlier, M. E.; DeFries, R. S.; Pennington, D.; Ordway, E.; Nelson, E.; Mickley, L.; Koplitz, S.

2013-12-01

Indonesia has experienced rapid land use change in past decades as forests and peatlands are cleared for agricultural development, including oil palm and timber plantations1. Fires are the predominant method of clearing and the subsequent emissions can have important public health impacts by contributing to regional particulate matter and ozone concentrations2. This regional haze was dramatically seen in Singapore during June 2013 due to the transport of emissions from fires in Sumatra. Our study is part of a larger project that will quantify the public health impact of various land use development scenarios for Sumatra over the coming decades. Here, we describe how we translate economic projections of land use change into future fire emissions inventories for GEOS-Chem atmospheric transport simulations. We relate past GFED3 fire emissions3 to detailed 1-km land use change data and MODIS fire radiative power observations, and apply these relationships to future estimates of land use change. The goal of this interdisciplinary project is to use modeling results to interact with policy makers and influence development strategies in ways that protect public health. 1Miettinen et al. 2011. Deforestation rates in insular Southeast Asia between 2000 and 2010. Glob. Change Biol.,17 (7), 2261-2270. 2Marlier et al. 2013. El Niño and health risks from landscape fire emissions in southeast Asia. Nature Clim. Change, 3, 131-136. 3van der Werf et al. 2010. Global fire emissions and the contribution of deforestation, savanna, forest, agricultural, and peat fires (1997-2009). Atmos. Chem. Physics, 10 (23), 11707-11735.

Relationship between calcium entry and ACh release in K+ -stimulated rat brain synaptosomes

International Nuclear Information System (INIS)

Suszkiw, J.B.; O'Leary, M.E.; Toth, G.P.

1986-01-01

This paper examines the pattern of Ca ++ entry-dependent ACh release in relation to the kinetics of Ca ++ entry, and its inactivation in rat brain synaptosomes exposed to 50 mM K 0 + for short and prolonged durations. Intrasynaptosomal ACh was radiolabeled from tritium-choline in the presence of 20 um Paraoxon to inhibit the acetylcholinesterase activity. The release of tritium-ACh was studied in superfused synaptosomal beds formed on glass microfiber filters and by rapid filtration. The intermittent stimulation of superfused synaptosomal beds by 3-min pulses of 50 mM K + evoked decremental output of tritium-ACh which reached nearly undetectable levels after the fifth stimulus

POLITIK RELASI ETNIK: MATRILINEALITAS DAN ETNIK MINORITAS CINA DI PADANG, SUMATRA BARAT

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Laila Kholid Alfirdaus

2014-06-01

Full Text Available Relasi etnik Minang dan etnik Cina di Padang, Sumatra Barat, menarik untuk dikaji. Melalui desk-study atas kajian Minang dan Cina, yang diperkuat dengan penelitian lapangan pada 2010 dan 2013 secara kualitatif dengan wawancara dan observasi, tulisan ini menemukan bahwa tidak cukup melihat relasi etnik Minang dan Cina dari perspektif ekonomi politik. Kita perlu memberikan perhatian terhadap faktor budaya dan budaya politik masyarakat Minang di Padang yang bercorak matrilineal. Jika literatur yang ada cenderung deterministik, menghasilkan dua pandangan yang secara ekstrem berbeda, yang dalam artikel ini disebut pandangan “manis” dan “sinis”, tulisan ini berargumen sebaliknya. Relasi etnik Minang dan etnik Cina tidak bisa secara buru-buru disebut “manis” hanya karena etnik Cina telah menetap dan berpartisipasi dalam kehidupan sosial ekonomi Padang sejak zaman penjajahan, atau karena Padang relatif minim kerusuhan dibandingkan kota lainnya. Demikian juga, ia tidak bisa serta merta dilihat secara “sinis” hanya karena segregasi sosial terlihat lebih kentara. Tulisan ini berargumen bahwa dua wajah yang secara bersamaan terjadi tidak lepas dari bentukan budaya Minang yang lekat dengan nilai-nilai matrilineal yang tertuang dalam ide feministik Bundo Kanduang Inter-etnic relations between Minang and Chinese in Padang, West Sumatra, that looks different compared to other societies in Indonesia is interesting to discuss. Through  a desk study about Minang and Chinese, being strengthened with fieldworks in 2010 and 2013 using qualitative methods in which in-depth interview and non-participatory observations, this article found that political economy perspective being used to explain Minang-Chinese relations is not enough. We need to pay attention on culture and political culture of Minangkabau society in Padang, that is matrilineal in the nature. While the existing lieratures tend to strictly classify the relations into “sweet” and �

Medan City: Development and governance under the decentralisation era

NARCIS (Netherlands)

Tarigan, A.K.M.; Samsura, D.A.A.; Sagala, S.; Pencawan, A.V.M.

2017-01-01

Over the last 30 years, Medan's economy has grown rapidly and has been the driver of the regional development in North Sumatra Province as well as the northern part of the Sumatra region. The recent adoption of decentralised public policies in Indonesia has to some extent influenced urban

31 CFR 363.38 - What happens if my financial institution returns an ACH debit?

Science.gov (United States)

2010-07-01

... TreasuryDirect § 363.38 What happens if my financial institution returns an ACH debit? If your designated financial institution returns an ACH debit, we reserve the right to reinitiate the debit at our option. We.... We are not responsible for any fees your financial institution may charge relating to returned ACH...

Crystal structures of Lymnaea stagnalis AChBP in complex with neonicotinoid insecticides imidacloprid and clothianidin.

Science.gov (United States)

Ihara, Makoto; Okajima, Toshihide; Yamashita, Atsuko; Oda, Takuma; Hirata, Koichi; Nishiwaki, Hisashi; Morimoto, Takako; Akamatsu, Miki; Ashikawa, Yuji; Kuroda, Shun'ichi; Mega, Ryosuke; Kuramitsu, Seiki; Sattelle, David B; Matsuda, Kazuhiko

2008-06-01

Neonicotinoid insecticides, which act on nicotinic acetylcholine receptors (nAChRs) in a variety of ways, have extremely low mammalian toxicity, yet the molecular basis of such actions is poorly understood. To elucidate the molecular basis for nAChR-neonicotinoid interactions, a surrogate protein, acetylcholine binding protein from Lymnaea stagnalis (Ls-AChBP) was crystallized in complex with neonicotinoid insecticides imidacloprid (IMI) or clothianidin (CTD). The crystal structures suggested that the guanidine moiety of IMI and CTD stacks with Tyr185, while the nitro group of IMI but not of CTD makes a hydrogen bond with Gln55. IMI showed higher binding affinity for Ls-AChBP than that of CTD, consistent with weaker CH-pi interactions in the Ls-AChBP-CTD complex than in the Ls-AChBP-IMI complex and the lack of the nitro group-Gln55 hydrogen bond in CTD. Yet, the NH at position 1 of CTD makes a hydrogen bond with the backbone carbonyl of Trp143, offering an explanation for the diverse actions of neonicotinoids on nAChRs.

Performance of coffee origin and genotype in organoleptic and physical quality of arabica coffee in North Sumatra Province of Indonesia

Science.gov (United States)

Malau, Sabam; Siagian, Albiner; Sirait, Bilter; Pandiangan, Samse

2017-09-01

The objective of this research was to determine effect of coffee origin and genotype on organoleptic and physical quality of Arabica coffea L. growing in North Sumatra. Seven districts treated as origins and 28 genotypes were chosen. The research was conducted with nested design with 3 factors. Organoleptic parameters were fragrance/aroma, flavor, aftertaste, acidity, body, uniformity, balance, clean cup, sweetness, overall and total score. Physical quality was green bean weight. The results revealed that origins affected significantly organoleptic quality. Coffee from Dairi showed the highest total score (90,82). Genotypes were significantly different in organoleptic quality. Genotype Da17, Da18, Da19, Da20 and Hu4 had the best total score (89,85 -91,68). Total score did not correlate with green bean weight but had positive correlation with altitude. Among organoleptic parameters, acidity was more significant for total score (r2 = 0,836). Altitude had more effect on acidity (r2 = 0,486).

Ultramicromorphological observation of Usnea longissima Ach ...

African Journals Online (AJOL)

The Usnea longissima Ach. grew as an epiphyte on Abies georgei and was collected at an altitude of 3640 m above sea level from the Pudacuo National Park in the Shangri-La County of the Diqing Tibetan Autonomous Prefecture in the Yunnan Province of China. Scanning electron microscopy revealed the ...

BEHAVIOR RISK FACTORS IN INDONESIA: NATIONAL HOUSEHOLD HEALTH SURVEY 2001

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Ch. M. Kristanti

2012-09-01

Full Text Available A series of National Household Health Surveys (NHHS reported the occurrence of epidemiological transition caused by demographic transition and prolonged economical diversity, Communicable diseases are still prevalent, followed by the emergence of Non Communicable Diseases (NCDs, which are due to an increasing level of behavior risk factors in the population. In the NHHS 2001, a morbidity survey collected information about behavioral risk indicators, whereas the WHO'S STEPwise approach was one of the study instruments. The 'WHO Step 1 questionnaire' was adapted with some modifications. Samples of NHHS, morbidity survey was sub-sample of module sample of National Social Economic Survey (NSES 2001. A sample of 15,148 people aged 10 years+ were analyzed to identify their behavior regarding smoking, alcohol consumption and physical activity. These findings are a representation of the national figures, which were presented by characteristics of the population such as: sex, age, residence, region and economic status. Economic status was divided into 5 strata, which were calculated from a quintile of household expenditure. The results showed that 29.7% of the population aged 10 years+ are daily smokers. This is more prevalent in males than females (58.9% vs. 3.7%. This behavior increases by age group, except for the oldest; there are slightly more smokers in rural areas than urban areas (31% vs. 28%, and no difference among regions (30-31%. Those with better economic status are less likely to smoke than poorer ones. Alcohol consumption is reportedly very low (2.7%, more prevalent in males than females (4.9% vs. 0.8%, and higher in rural areas than urban areas (3.1% vs. 2.1%. Eastern Indonesia, was higher than Sumatra, Java and Bali (6.3%, 4.7%, and 1.2% respectively. There were no differences in alcohol consumption according to economic status'.' Physical inactivity is very high (68%, more prevalent in females than males (73% vs. 63%, and higher in

Pollinating fig wasps: genetic consequences of island recolonization

NARCIS (Netherlands)

Zavodna, M.; Arens, P.; Partomihardjo, T.; Vosman, B.; van Dijk, P.J.; Van Damme, J.M.M.

2005-01-01

The levels of genetic diversity and gene flow may influence the long-term persistence of populations. Using microsatellite markers, we investigated genetic diversity and genetic differentiation in island (Krakatau archipelago, Indonesia) and mainland (Java and Sumatra, Indonesia) populations of

Carbon stock and turnover in riparian soils under lowland rainforest transformation systems on Sumatra, Indonesia

Science.gov (United States)

Hennings, Nina; Kuzyakov, Yakov

2017-04-01

In many tropical areas, rainforests are being cleared in order to exploit timber and other forest products as well as plant crops for food, feed and fuel use. The determinants of different patterns of deforestation and the roles of resulting transformation systems of tropical riparian rainforests for ecological functions have yet received little attention in scientific research. Especially C stocks in riparian zones are strongly affected by climate and land use changes that lead to changes in water regime and ground water level drops. We investigated the effects of land transformations in riparian ecosystems of Sumatra, on soil C content, stocks and decomposability at the landscape scale. We compare C losses in transformation systems and rainforests and estimate the contribution of soil erosion and organic matter mineralization. Further, these losses are related to changing water level and temperature increase along increasing distance to the stream. This approach is based on changing δ13C values of SOC in the topsoil as compared to those in subsoil. The shift of δ13C of SOC in the topsoil from the linear regression calculated by δ13C value with log(SOC) in the topsoil represents the modification of the C turnover rate in the top soil. Erosion is estimated by the shift of the δ13C value of SOC in the subsoil under plantations. Further, the δ13C and δ15N soil profiles and their comparison with litter of local vegetation, can be used to estimate the contribution of autochthonous and allochthonous organics to soil C stocks. Preliminary results show strong increase of erosive losses, increased decomposition with land-use transformation and decrease of C stocks with decreasing water table.

Pharmacological and immunochemical characterization of α2* nicotinic acetylcholine receptors (nAChRs) in mouse brain

Science.gov (United States)

Whiteaker, Paul; Wilking, Jennifer A; Brown, Robert WB; Brennan, Robert J; Collins, Allan C; Lindstrom, Jon M; Boulter, Jim

2009-01-01

Aim: α2 nAChR subunit mRNA expression in mice is most intense in the olfactory bulbs and interpeduncular nucleus. We aimed to investigate the properties of α2* nAChRs in these mouse brain regions. Methods: α2 nAChR subunit-null mutant mice were engineered. Pharmacological and immunoprecipitation studies were used to determine the composition of α2 subunit-containing (α2*) nAChRs in these two regions. Results: [125I]Epibatidine (200 pmol/L) autoradiography and saturation binding demonstrated that α2 deletion reduces nAChR expression in both olfactory bulbs and interpeduncular nucleus (by 4.8±1.7 and 92±26 fmol̇mg-1 protein, respectively). Pharmacological characterization using the β2-selective drug A85380 to inhibit [125I]epibatidine binding proved inconclusive, so immunoprecipitation methods were used to further characterize α2* nAChRs. Protocols were established to immunoprecipitate β2 and β4 nAChRs. Immunoprecipitation specificity was ascertained using tissue from β2- and β4-null mutant mice, and efficacy was good (>90% of β2* and >80% of β4* nAChRs were routinely recovered). Conclusion: Immunoprecipitation experiments indicated that interpeduncular nucleus α2* nAChRs predominantly contain β2 subunits, while those in olfactory bulbs contain mainly β4 subunits. In addition, the immunoprecipitation evidence indicated that both nuclei, but especially the interpeduncular nucleus, express nAChR complexes containing both β2 and β4 subunits. PMID:19498420

Biochemical effects of glyphosate based herbicide, Excel Mera 71 on enzyme activities of acetylcholinesterase (AChE), lipid peroxidation (LPO), catalase (CAT), glutathione-S-transferase (GST) and protein content on teleostean fishes.

Science.gov (United States)

Samanta, Palas; Pal, Sandipan; Mukherjee, Aloke Kumar; Ghosh, Apurba Ratan

2014-09-01

Effects of glyphosate based herbicide, Excel Mera 71 at a dose of 17.20mg/l on enzyme activities of acetylcholinesterase (AChE), lipid peroxidation (LPO), catalase (CAT), glutathione-S-transferase (GST) and protein content were measured in different tissues of two Indian air-breathing teleosts, Anabas testudineus (Bloch) and Heteropneustes fossilis (Bloch) during an exposure period of 30 days under laboratory condition. AChE activity was significantly increased in all the investigated tissues of both fish species and maximum elevation was observed in brain of H. fossilis, while spinal cord of A. testudineus showed minimum increment. Fishes showed significant increase LPO levels in all the tissues; highest was observed in gill of A. testudineus but lowest LPO level was observed in muscle of H. fossilis. CAT was also enhanced in both the fishes, while GST activity in liver diminished substantially and minimum was observed in liver of A. testudineus. Total protein content showed decreased value in all the tissues, maximum reduction was observed in liver and minimum in brain of A. testudineus and H. fossilis respectively. The results indicated that Excel Mera 71 caused serious alterations in the enzyme activities resulting into severe deterioration of fish health; so, AChE, LPO, CAT and GST can be used as suitable indicators of herbicidal toxicity. Copyright © 2014 Elsevier Inc. All rights reserved.

The challenge of installing a tsunami early warning system in the vicinity of the Sunda Arc, Indonesia

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J. Lauterjung

2010-04-01

Full Text Available Indonesia is located along the most prominent active continental margin in the Indian Ocean, the so-called Sunda Arc and, therefore, is one of the most threatened regions of the world in terms of natural hazards such as earthquakes, volcanoes, and tsunamis. On 26 December 2004 the third largest earthquake ever instrumentally recorded (magnitude 9.3, Stein and Okal, 2005 occurred off-shore northern Sumatra and triggered a mega-tsunami affecting the whole Indian Ocean. Almost a quarter of a million people were killed, as the region was not prepared either in terms of early-warning or in terms of disaster response.

In order to be able to provide, in future, a fast and reliable warning procedure for the population, Germany, immediately after the catastrophe, offered during the UN World Conference on Disaster Reduction in Kobe, Hyogo/Japan in January 2005 technical support for the development and installation of a tsunami early warning system for the Indian Ocean in addition to assistance in capacity building in particular for local communities. This offer was accepted by Indonesia but also by other countries like Sri Lanka, the Maldives and some East-African countries. Anyhow the main focus of our activities has been carried out in Indonesia as the main source of tsunami threat for the entire Indian Ocean. Challenging for the technical concept of this warning system are the extremely short warning times for Indonesia, due to its vicinity to the Sunda Arc. For this reason the German Indonesian Tsunami Early Warning System (GITEWS integrates different modern and new scientific monitoring technologies and analysis methods.

Optogenetic release of ACh induces rhythmic bursts of perisomatic IPSCs in hippocampus.

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Daniel A Nagode

Full Text Available Acetylcholine (ACh influences a vast array of phenomena in cortical systems. It alters many ionic conductances and neuronal firing behavior, often by regulating membrane potential oscillations in populations of cells. Synaptic inhibition has crucial roles in many forms of oscillation, and cholinergic mechanisms regulate both oscillations and synaptic inhibition. In vitro investigations using bath-application of cholinergic receptor agonists, or bulk tissue electrical stimulation to release endogenous ACh, have led to insights into cholinergic function, but questions remain because of the relative lack of selectivity of these forms of stimulation. To investigate the effects of selective release of ACh on interneurons and oscillations, we used an optogenetic approach in which the light-sensitive non-selective cation channel, Channelrhodopsin2 (ChR2, was virally delivered to cholinergic projection neurons in the medial septum/diagonal band of Broca (MS/DBB of adult mice expressing Cre-recombinase under the control of the choline-acetyltransferase (ChAT promoter. Acute hippocampal slices obtained from these animals weeks later revealed ChR2 expression in cholinergic axons. Brief trains of blue light pulses delivered to untreated slices initiated bursts of ACh-evoked, inhibitory post-synaptic currents (L-IPSCs in CA1 pyramidal cells that lasted for 10's of seconds after the light stimulation ceased. L-IPSC occurred more reliably in slices treated with eserine and a very low concentration of 4-AP, which were therefore used in most experiments. The rhythmic, L-IPSCs were driven primarily by muscarinic ACh receptors (mAChRs, and could be suppressed by endocannabinoid release from pyramidal cells. Finally, low-frequency oscillations (LFOs of local field potentials (LFPs were significantly cross-correlated with the L-IPSCs, and reversal of the LFPs near s. pyramidale confirmed that the LFPs were driven by perisomatic inhibition. This optogenetic approach

Penelitian tentang ukuran acuan sepatu pelajar wanita indonesia tingkat SD, SLTP dan SLTA

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Sri Bandi

1995-06-01

Full Text Available The study was subjected to 500 Indonesia School girls from North Sumatra Province (Medan, West Java Province (Bandung, Central – Java Province (Semarang, East-Java Province (Surabaya and DKI Jaya. 100 samples of foot sizes which represented foot sizes of SD, SLTP and SLTA School girls werw taken from each province. By analyzing the data of foot sizes of the school girls, a suggestion on design of shoe lasts seritable with the shape and type of foot, fits and conform the requirements to be used as lost in shoe manufacturing could be proposed. The results of data analyse shown that : 1. The length of soles ranged from 30-35, 5 PS, the mean of which was 33 PS. 2. Instep girth ranged withim E, F, G, I.3. The foot sizes scattered between (4-17 years of age at (32-35 PS.

Regulation of ACh release from guinea pig bladder urothelial cells: potential role in bladder filling sensations.

Science.gov (United States)

McLatchie, L M; Young, J S; Fry, C H

2014-07-01

The aim of this study was to quantify and characterize the mechanism of non-neuronal ACh release from bladder urothelial cells and to determine if urothelial cells could be a site of action of anti-muscarinic drugs. A novel technique was developed whereby ACh could be measured from freshly isolated guinea pig urothelial cells in suspension following mechanical stimulation. Various agents were used to manipulate possible ACh release pathways in turn and to study the effects of muscarinic receptor activation and inhibition on urothelial ATP release. Minimal mechanical stimulus achieved full ACh release, indicating a small dynamic range and possible all-or-none signal. ACh release involved a mechanism dependent on the anion channel CFTR and intracellular calcium concentration, but was independent of extracellular calcium, vesicular trafficking, connexins or pannexins, organic cation transporters and was not affected by botulinum-A toxin. Stimulating ACh receptors increased ATP production and antagonizing them reduced ATP release, suggesting a link between ACh and ATP release. These results suggest that release of non-neuronal ACh from the urothelium is large enough and well located to act as a modulator of ATP release. It is hypothesized that this pathway may contribute to the actions of anti-muscarinic drugs in reducing the symptoms of lower urinary tract syndromes. Additionally the involvement of CFTR in ACh release suggests an exciting new direction for the treatment of these conditions. © 2014 The British Pharmacological Society.

The influence of 19th century Dutch Colonial Orientalism in spreading Kubah (Islamic Dome and Middle-Eastern architectural styles for mosques in Sumatra

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Kemas Ridwan Kurniawan

2012-12-01

Full Text Available This paper researches the possible representation of Orientalism and the spread of Middle Eastern inspired architecture in Indonesia, particularly in Dutch colonial practices in the 19th-century. It challenges the dominant opinion of the people that the Middle Eastern merchants in the East Indies were the only ones that introduced the use of kubah (dome shape to mosque architecture in Indonesia. Consequently, this paper has two objectives: firstly, by looking at the historical relationship between religious architecture and colonial politics, especially in the construction of the Baiturrahman Mosque in Aceh and secondly, by considering Orientalism (besides those beliefs existing in Moslem communities to be one of important intellectual agencies for mixing architectural cultural symbols. The socio-political narrative is analyzed in the context of an Indonesian-Islamic building typology and the relationship between space, people, power, and time. The research itself is based on literature searches specifically related to colonialism and orientalism, along with archive studies and field investigations, including interviews with related historical experts. In order to replace 'non-architectural' traditional roofs, which were considered as representing a less-developed civilization, Dutch political interests were instrumental in bringing the universally-styled Middle Eastern architectural elements into mosque architecture of the Netherland Indies. This political motivation ultimately led to the spread of kubah (dome as an architectonic element in Indonesian mosque architecture throughout the archipelago, specifically in Sumatra.

Distribution and burial of organic carbon in sediments from the Indian Ocean upwelling region off Java and Sumatra, Indonesia

Science.gov (United States)

Baumgart, Anne; Jennerjahn, Tim; Mohtadi, Mahyar; Hebbeln, Dierk

2010-03-01

Sediments were sampled and oxygen profiles of the water column were determined in the Indian Ocean off west and south Indonesia in order to obtain information on the production, transformation, and accumulation of organic matter (OM). The stable carbon isotope composition (δ 13C org) in combination with C/N ratios depicts the almost exclusively marine origin of sedimentary organic matter in the entire study area. Maximum concentrations of organic carbon (C org) and nitrogen (N) of 3.0% and 0.31%, respectively, were observed in the northern Mentawai Basin and in the Savu and Lombok basins. Minimum δ 15N values of 3.7‰ were measured in the northern Mentawai Basin, whereas they varied around 5.4‰ at stations outside this region. Minimum bottom water oxygen concentrations of 1.1 mL L -1, corresponding to an oxygen saturation of 16.1%, indicate reduced ventilation of bottom water in the northern Mentawai Basin. This low bottom water oxygen reduces organic matter decomposition, which is demonstrated by the almost unaltered isotopic composition of nitrogen during early diagenesis. Maximum C org accumulation rates (CARs) were measured in the Lombok (10.4 g C m -2 yr -1) and northern Mentawai basins (5.2 g C m -2 yr -1). Upwelling-induced high productivity is responsible for the high CAR off East Java, Lombok, and Savu Basins, while a better OM preservation caused by reduced ventilation contributes to the high CAR observed in the northern Mentawai Basin. The interplay between primary production, remineralisation, and organic carbon burial determines the regional heterogeneity. CAR in the Indian Ocean upwelling region off Indonesia is lower than in the Peru and Chile upwellings, but in the same order of magnitude as in the Arabian Sea, the Benguela, and Gulf of California upwellings, and corresponds to 0.1-7.1% of the global ocean carbon burial. This demonstrates the relevance of the Indian Ocean margin off Indonesia for the global OM burial.

INVESTIGATION OF DISSOLVED SULPHATE IN VARIOUS GEOTHERMAL FIELDS OF SUMATRA USING OXYGEN AND SULPHUR ISOTOPES

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E. Ristin Pujiindiyati

2010-06-01

Full Text Available There are at least 30 high temperature systems; eleven active volcanoes, five degassing volcanoes and one caldera volcano controlled by Sumatra Fault Zone over a length of 1700 km. To understand this geothermal field system, some information about geochemistry including isotope composition in its fluid is needed. Sulphur-34 and oxygen-18 isotopes in dissolved sulphate pair have been used to determine the origin of acidic fluid of sulphate and to evaluate the process involved. The fluids from eight hot springs, two fumaroles, four deep wells and crater have been collected in along Sumatra geothermal fields. Sulphur-34 (d 34S (SO4, 0/00 CDT and oxygen-18 (d 18O (SO4, 0/00 SMOW in sulphate is analyzed according to Robinson-Kusakabe and Rafter method, respectively. The d 34S (SO4 values from Sibayak wells are more enriched of 16.8 0/00 to 18.2 0/0 that may indicate the dissolution of anhydrite minerals or isotope partitioning in hydration of SO2. The d 34S (SO4 values from two fumaroles (Pusuk Bukit - North Sumatra and Rantau Dadap - South Sumatra are at depleted value of -0.150/00 and 1.80/00, those are close to d 34S from magmatic sulphur.  In general, the d 34S (SO4 of springs spread in a wide range of 5.250/00 to14.20/00 and show a mixing process between atmospheric sulphate and sulphate from deep wells. The d 18O (SO4 from wells exhibits depleted value around -3.60/00 suggesting that 87.5% of sulphate oxygen is derived from groundwater oxygen and 12.5% is derived from atmospheric molecular oxygen in sulphide oxidation reaction. In the other hand, hot springs (except Semurup, crater and fumaroles have enriched value of d 18O (SO4. These enriched values suggest that a higher percentage of atmospherically derived oxygen compared to those from the depth.   Keywords: isotope, geothermal, Sumatra

Atmospheric processes in reaction of Northern Sumatra Earthquake sequence Dec 2004-Apr 2005

Science.gov (United States)

Ouzounov, D.; Pulinets, S.; Cervone, G.; Singh, R.; Taylor, P.

2005-05-01

This work describes our first results in analyzing data from different and independent sources ûemitted long-wavelength radiation (OLR), surface latent heat flux (SHLF) and GPS Total Electron Content (TEC) collected from ground based (GPS) and satellite TIR (thermal infra-red) data sources (NOAA/AVHRR, MODIS). We found atmosphere and ionosphere anomalies one week prior to both the Sumatra-Andaman Islands earthquake (Dec 26, 2004) and M 8.7 - Northern Sumatra, March 28, 2005. We analyzed 118 days of data from December 1, 2004 through April 1, 2005 for the area (0°-10°,north latitude and 90°-100° east longitude) which included 125 earthquakes with M>5.5. Recent analysis of the continuous OLR from the Earth surface indicates anomalous variations (on top of the atmosphere) prior to a number of medium to large earthquakes. In the case of M 9.0 - Sumatra-Andaman Islands event, compared to the reference fields for the months of December between 2001 and 2004, we found strongly OLR anomalous +80 W/m2 signals (two sigma) along the epicentral area on Dec 21, 2004 five days before the event. In the case of M8.7 March 28, 2005 anomalues signatures over the epicenter appears on March 26 is much weaker (only +20W/m2) and have a different topology. Anomalous values of SHLF associated with M9.0 - Sumatra-Andaman Islands were found on Dec 22, 2005 (SLHF +280Wm2) and less intensity on Mar 23, 2005 (SLHF +180Wm2). Ionospheric variations (GPS/TEC) associated with the Northern Sumatra events were determine by five Regional GPS network stations (COCO, BAKO, NTUS, HYDE and BAST2). For every station time series of the vertical TEC (VTEC) were computed together with correlation with the Dst index. On December 22, four days prior to the M9.0 quake GPS/TEC data reach the monthly maximum for COCO with minor DST activity. For the M 8.7-March 28 event, the increased values of GPS/TEC were observed during four days (March 22-25) in quiet geomagnetic background. Our results need additional

Identification and Expression of Acetylcholinesterase in Octopus vulgaris Arm Development and Regeneration: a Conserved Role for ACHE?

Science.gov (United States)

Fossati, Sara Maria; Candiani, Simona; Nödl, Marie-Therese; Maragliano, Luca; Pennuto, Maria; Domingues, Pedro; Benfenati, Fabio; Pestarino, Mario; Zullo, Letizia

2015-08-01

Acetylcholinesterase (ACHE) is a glycoprotein with a key role in terminating synaptic transmission in cholinergic neurons of both vertebrates and invertebrates. ACHE is also involved in the regulation of cell growth and morphogenesis during embryogenesis and regeneration acting through its non-cholinergic sites. The mollusk Octopus vulgaris provides a powerful model for investigating the mechanisms underlying tissue morphogenesis due to its high regenerative power. Here, we performed a comparative investigation of arm morphogenesis during adult arm regeneration and embryonic arm development which may provide insights on the conserved ACHE pathways. In this study, we cloned and characterized O. vulgaris ACHE, finding a single highly conserved ACHE hydrophobic variant, characterized by prototypical catalytic sites and a putative consensus region for a glycosylphosphatidylinositol (GPI)-anchor attachment at the COOH-terminus. We then show that its expression level is correlated to the stage of morphogenesis in both adult and embryonic arm. In particular, ACHE is localized in typical neuronal sites when adult-like arm morphology is established and in differentiating cell locations during the early stages of arm morphogenesis. This possibility is also supported by the presence in the ACHE sequence and model structure of both cholinergic and non-cholinergic sites. This study provides insights into ACHE conserved roles during processes of arm morphogenesis. In addition, our modeling study offers a solid basis for predicting the interaction of the ACHE domains with pharmacological blockers for in vivo investigations. We therefore suggest ACHE as a target for the regulation of tissue morphogenesis.

Strategic Service Analysis Pusako Hotel to Increase Occupancy Rate

OpenAIRE

Tyas, Anggi Fitrining; Wibowo, Satya Aditya

2013-01-01

The tourism industry is the fourth largest foreign exchange earner for Indonesia after oil and gas, palm oil, rubber and processed in 2011. This industry is expected to continue to grow and expand in Indonesia in line with government programs to take advantage of all the potential of tourism in Indonesia. West Sumatra, especially the Bukittinggi is one of the favorite tourist destinations in Indonesia also felt the positive effects of tourism development in Indonesia, namely the increasing nu...

Synthesis, spectroscopic, computational (DFT/B3LYP), AChE inhibition and antioxidant studies of imidazole derivative

Science.gov (United States)

Ahmad, Faheem; Alam, Mohammad Jane; Alam, Mahboob; Azaz, Shaista; Parveen, Mehtab; Park, Soonheum; Ahmad, Shabbir

2018-01-01

The present study reports the synthesis and evaluation of biological properties of 3a,8a-dihydroxy-8-oxo-1,3,3a,8a-tetrahydroindeno[1,2-d]imidazol-2(1H)-iminium chloride (3). The structure was confirmed by the FTIR, NMR, MS, CHN microanalysis and X-ray crystallographic analysis. Quantum chemical calculations have been performed at B3LYP-D3/6-311++G(d,p) level of theory to study the molecular geometry, IR, (1H and 13C) NMR, UV/Vis spectra and other molecular parameters of the asymmetric unit of crystal of imidazole compound (3). An empirical dispersion correction to hybrid functional (B3LYP-D3) has been incorporated in the present calculations due to presence of non-covalent interaction, Cl⋯H-O, in the present compound. The remarkable agreement has been observed between theoretical data and those measured experimentally. Moreover, the Hirshfeld analysis was carried out to ascertain the secondary interactions and associated 2D fingerprint plots. The synthesized imidazole derivative showed promising antioxidant property and inhibitory activity against acetylcholinesterase (AChE). Molecular docking was also performed in order to explain in silico antioxidant studies and to ascertain the probable binding mode of compound with the amino acid residues of protein.

Capacity Development and Strengthening for Energy Policy formulation and implementation of Sustainable Energy Projects in Indonesia CASINDO. Deliverable No. 13. Integration of Renewable Energy Technologies in the national curriculum SPECTRUM

Energy Technology Data Exchange (ETDEWEB)

Kamphuis, E. [ETC Nederland, Leusden (Netherlands); Permana, I. [Technical Education Development Centre TEDC, Bandung (Indonesia)

2011-11-15

The overall objective of the CASINDO programme is to establish a self-sustaining and self-developing structure at both the national and regional level to build and strengthen human capacity to enable the provinces of North Sumatra, Yogyakarta, Central Java, West Nusa Tenggara and Papua to formulate sound policies for renewable energy and energy efficiency and to develop and implement sustainable energy projects. This report focuses on the achievements for settling a national curriculum for Renewable Energy Technologies (RET) within the framework of national programme SPECTRUM, which includes all curricula of the medium technical schools in Indonesia.

Effect of mangrove rehabilitation on socio-cultural of pulau sembilan society, North Sumatera, Indonesia

Science.gov (United States)

Basyuni, M.; Harahap, F. K.; Wati, R.; Putri, L. A. P.

2018-03-01

Mangrove forests in North Sumatera, Indonesia existed in the east coast of Sumatera Island and commonly found in Serdang Bedagai, Deli Serdang, Batubara, Tanjung Balai, Asahan, Labuhanbatu until Langkat. The effect of rehabilitated mangrove on socio-cultural of Pulau Sembilan society, Langkat, North Sumatra, Indonesia was studied. The rehabilitation was carried on May 2015 using indirect planting of 2,100 Rhizophora apiculata seedlings. Two times of observations, May and August 2015 were made to monitor and evaluate 400 rehabilitated seedlings. Sixty of 600 households were surveyed using Slovin formula to obtain community perspective on the socio-cultural impact of mangrove rehabilitation. Results showed that the growth of R. apiculata seedlings were 73.3% during four months observations. The restoration affected 65, 58.3 and 35 % of economic, social, and cultural of Pulau Sembilan society, respectively. The perspective of community on the land-use change led to 66.7% was disagreed that mangroves to be converted, 60% respondents stated that mangrove condition was degraded even worse than previously existed. Therefore, to resolve the degraded mangrove, community perspective on rehabilitation was needed (85.5%) and actively involved (88.3%). The present results suggested that the high recommendation for a rehabilitation program for the degraded area was by integrating the stake holders (government, university, and non-governmental organization) and local communities count on the mangrove ecosystems.

Chemical chaperones exceed the chaperone effects of RIC-3 in promoting assembly of functional α7 AChRs.

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Alexander Kuryatov

Full Text Available Functional α7 nicotinic acetylcholine receptors (AChRs do not assemble efficiently in cells transfected with α7 subunits unless the cells are also transfected with the chaperone protein RIC-3. Despite the presence of RIC-3, large amounts of these subunits remain improperly assembled. Thus, additional chaperone proteins are probably required for efficient assembly of α7 AChRs. Cholinergic ligands can act as pharmacological chaperones to promote assembly of mature AChRs and upregulate the amount of functional AChRs. In addition, we have found that the chemical chaperones 4-phenylbutyric acid (PBA and valproic acid (VPA greatly increase the amount of functional α7 AChRs produced in a cell line expressing both α7 and RIC-3. Increased α7 AChR expression allows assay of drug action using a membrane potential-sensitive fluorescent indicator. Both PBA and VPA also increase α7 expression in the SH-SY5Y neuroblastoma cell line that endogenously expresses α7 AChRs. VPA increases expression of endogenous α7 AChRs in hippocampal neurons but PBA does not. RIC-3 is insufficient for optimal assembly of α7 AChRs, but provides assay conditions for detecting additional chaperones. Chemical chaperones are a useful pragmatic approach to express high levels of human α7 AChRs for drug selection and characterization and possibly to increase α7 expression in vivo.

Pterygium in Indonesia: prevalence, severity and risk factors

Science.gov (United States)

Gazzard, G; Saw, S-M; Farook, M; Koh, D; Widjaja, D; Chia, S-E; Hong, C-Y; Tan, D T H

2002-01-01

Aim: To determine prevalence rates, severity, and risk factors for pterygium in adults in provincial Indonesia and to validate a clinical grading scheme in a population based setting. Methods: A population based prevalence survey of 1210 adults aged 21 years and above was conducted in five rural villages and one provincial town in Riau province, Sumatra, Indonesia, an area near to the equator. A one stage household cluster sampling procedure was employed: 100 households were randomly selected from each village or town. Pterygia were graded for severity (T1 to T3, by visibility of episcleral vessels) and the basal and apical extent measured by an ophthalmologist (GG) with a hand held slit lamp. Refraction was measured by hand held autorefractor (Retinomax). Face to face household interviews assessed outdoor activity, occupation, and smoking. The participation rate was 96.7%. Results: The mean age was 36.6 years (SD 13.1), 612 were male. The age adjusted prevalence rate of any pterygium was 10.0% (95% confidence intervals (CI) 8.2 to 11.7) and of bilateral pterygia was 4.1% (95% CI 2.9 to 5.3). There was a significant dose-response relation with age (2.9% (95% CI 0.4 to 5.8) for 21–29 years versus 17.3% (95% CI 10.4 to 24.2) 50 years and above; p for trend <0.001) and occupations with more time outdoors (p for trend = 0.02). This was true for both sexes, all grades of lesion (T1 to T3), and bilateral disease. A multivariate logistic regression model showed pterygium was independently related to increasing age and outdoor activity 10 years earlier. The mean basal diameter = 3.3 mm (SD 1.51, range 0.1–9.5) and extent from limbus = 1.4 mm (SD 1.18, range 0.1–8.0). Higher grade pterygia were larger for basal and apical extent (p for trend <0.001). The presence of pterygium was associated with astigmatism (defined as cylinder at least −0.5 dioptres (D); p <0.001). This association increased with increasing grade of lesion (p for trend <0.001). Median cylinder for

Capacity Development and Strengthening for Energy Policy formulation and implementation of Sustainable Energy Projects in Indonesia CASINDO. Deliverable No. 16. Development and execution of pilot research projects at the CASINDO partner universities

Energy Technology Data Exchange (ETDEWEB)

Wijnker, M. [Eindhoven University of Technology TUE, Eindhoven (Netherlands)

2011-09-15

The overall objective of the CASINDO programme is to establish a self-sustaining and self-developing structure at both the national and regional level to build and strengthen human capacity to enable the provinces of North Sumatra, Yogyakarta, Central Java, West Nusa Tenggara and Papua to formulate sound policies for renewable energy and energy efficiency and to develop and implement sustainable energy projects. Each of the five Indonesian universities managed to develop pilot research projects and wrote research proposals to outline and strengthen their ideas. All of the universities also purchased equipment for the purpose of executing this research. UNCEN (Cenderawasih University, Jayapura, Papua, Indonesia) and UNDIP (Diponegoro University in Semarang, Java, Indonesia) managed to finalize their research within the project period and wrote reports on their results. The other universities could not yet present results due to delay in one or several of the steps within the procedure.

MANGROVE RESOURCE USES BY LOCAL COMMUNITY IN INDONESIA

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Cecep Kusmana

2016-12-01

Full Text Available Indonesia is an archipelagic country of more than 17,504 islands (28 big islands and 17,475 small islands with the length of coastline estimated at 95,181 km, which bears mangroves from several meters to several kilometers. They are estimated at 3.2 million hectares growing extensively in the five big islands (Java, Sumatra, Kalimantan, Sulawesi, Papua with various community types comprising of about 157 species (52 species of trees, 21 species of shrubs, 13 species of lyana, seven species of palms, 14 species of grasses, eight species of herbs, three species of parasites, 36 species of epiphytes, three species of ferns. The mangroves resources in Indonesia involve the flora, fauna, and land resources which are needed for supporting many kinds of human needs, especially for local community living in surrounding mangroves. For centuries, the Indonesian people have traditionally utilized mangroves. The most significant value of mangrove utilization is the gathering of forest products, classified into timber and non-timber products. The timber refers to poles and firewood, charcoal, and construction materials (e.g. housing material and fishing gears; the latter include tannin, medicines, dye, nypa thatch and shingles, nypa sap for vinegar and winemaking, and food drinks. Traditional uses of mangrove forest products are mainly the direct utilization of the products, usually in small scale. Beside of those, local community are used to utilizing associated mangrove aquatic fauna for supporting their daily life as well as utilizing mangrove habitat for multipurpose uses through agroforestry techniques (silvofishery, agrosilvofishery, agrosilvopastoralfishery systems. So that, the good mangrove ecosystem serves luxurious both flora and fauna species (biodiversity as well as their abundance for signicantly supporting the welfare of coastal community

Lack of Ach1 CoA-Transferase Triggers Apoptosis and Decreases Chronological Lifespan in Yeast

International Nuclear Information System (INIS)

Orlandi, Ivan; Casatta, Nadia; Vai, Marina

2012-01-01

ACH1 encodes a mitochondrial enzyme of Saccharomyces cerevisiae endowed with CoA-transferase activity. It catalyzes the CoASH transfer from succinyl-CoA to acetate generating acetyl-CoA. It is known that ACH1 inactivation results in growth defects on media containing acetate as a sole carbon and energy source which are particularly severe at low pH. Here, we show that chronological aging ach1Δ cells which accumulate a high amount of extracellular acetic acid display a reduced chronological lifespan. The faster drop of cell survival is completely abrogated by alleviating the acid stress either by a calorie restricted regimen that prevents acetic acid production or by transferring chronologically aging mutant cells to water. Moreover, the short-lived phenotype of ach1Δ cells is accompanied by reactive oxygen species accumulation, severe mitochondrial damage, and an early insurgence of apoptosis. A similar pattern of endogenous severe oxidative stress is observed when ach1Δ cells are cultured using acetic acid as a carbon source under acidic conditions. On the whole, our data provide further evidence of the role of acetic acid as cell-extrinsic mediator of cell death during chronological aging and highlight a primary role of Ach1 enzymatic activity in acetic acid detoxification which is important for mitochondrial functionality.

Prevalence and risk factors associated with dry eye symptoms: a population based study in Indonesia

Science.gov (United States)

Lee, A J; Lee, J; Saw, S-M; Gazzard, G; Koh, D; Widjaja, D; Tan, D T H

2002-01-01

Aim: To determine the prevalence and identify associated risk factors for dry eye syndrome in a population in Sumatra, Indonesia. Methods: A one stage cluster sampling procedure was conducted to randomly select 100 households in each of the five rural villages and one provincial town of the Riau province, Indonesia, from April to June 2001. Interviewers collected demographic, lifestyle, and medical data from 1058 participants aged 21 years or over. Symptoms of dry eye were assessed using a six item validated questionnaire. Presence of one or more of the six dry eye symptoms often or all the time was analysed. Presence of pterygium was documented. Results: Prevalence of one or more of the six dry eye symptoms often or all the time adjusted for age was 27.5% (95% confidence interval (CI) 24.8 to 30.2). After adjusting for all significant variables, independent risk factors for dry eye were pterygium (p<0.001, multivariate odds ratio (OR) 1.8; 95% CI 1.4 to 2.5) and a history of current cigarette smoking (p=0.05, multivariate OR 1.5; 95% CI 1.0 to 2.2). Conclusions: This population based study provides prevalence rates of dry eye symptoms in a tropical developing nation. From our findings, pterygium is a possible independent risk factor for dry eye symptoms. PMID:12446361

The 26 December 2004 Sumatra tsunami recorded on the coast of ...

African Journals Online (AJOL)

Analysis of sea-level data obtained from the Atlantic Global Sea Level Observing System (GLOSS) sea-level station at Takoradi, Ghana, West Africa, clearly reveals a tsunami signal associated with the Mw = 9.3 Sumatra earthquake of 26 December 2004 in the Indian Ocean. The tsunami arrived at this location on 27 ...

Factors influencing the use of antenatal care in rural West Sumatra, Indonesia

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Agus Yenita

2012-02-01

Full Text Available Abstract Background Every year, nearly half a million women and girls needlessly die as a result of complications during pregnancy, childbirth or the 6 weeks following delivery. Almost all (99% of these deaths occur in developing countries. The study aim was to describe the factors related to low visits for antenatal care (ANC services among pregnant women in Indonesia. Method A total of 145 of 200 married women of reproductive age who were pregnant or had experienced birth responded to the questionnaire about their ANC visits. We developed a questionnaire containing 35 items and four sections. Section one and two included the women's socio demographics, section three about basic knowledge of pregnancy and section four contained two subsections about preferences about midwives and preferences about Traditional Birth Attendant (TBA and the second subsections were traditional beliefs. Data were collected using a convenience sampling strategy during July and August 2010, from 10 villages in the Tanjung Emas. Multiple regression analysis was used for preference for types of providers. Results Three-quarter of respondents (77.9% received ANC more than four times. The other 22.1% received ANC less than four times. 59.4% received ANC visits during pregnancy, which was statistically significant compared to multiparous (p = 0.001. Women who were encouraged by their family to receive ANC had statistically significant higher traditional belief scores compared to those who encouraged themselves (p = 0.003. Preference for TBAs was most strongly affected by traditional beliefs (p p Conclusions Parity was the factor influencing women's receiving less than the recommended four ANC visits during pregnancy. Women who were encouraged by their family to get ANC services had higher traditional beliefs score than women who encouraged themselves. Moreover, traditional beliefs followed by lower income families had the greater influence over preferring TBAs, with the

Bank Indonesia dalam Tata Pemerintahan Indonesia

OpenAIRE

Ismail, Maqdir

2010-01-01

This research focuses on problems as follows: First, position and role of Bank Indonesia as a state body in Indonesia; Second, independency of central bank in performing its monetary function. This research is a juridical normative research using primary legal source which is legislation concerning central bank. Data is collected through document study and literary study. This research concludes that position of Bank Indonesia as a legal entity should have been included in the explanation of ...

Bank Indonesia Dalam Tata Pemerintahan Indonesia

OpenAIRE

Ismail, Maqdir

2010-01-01

This research focuses on problems as follows: First, position and role of Bank Indonesia as a state body in Indonesia; Second, independency of central bank in performing its monetary function. This research is a juridical normative research using primary legal source which is legislation concerning central bank. Data is collected through document study and literary study. This research concludes that position of Bank Indonesia as a legal entity should have been included in the explanation of ...

Progress in Malesian botany

NARCIS (Netherlands)

NN,

1987-01-01

Tree Flora of Indonesia checklists under editorship of Dr. T.C. WHITMORE and Dr. I.G.M. TANTRA (Forest Dept., Bali). Sumatra has now been distributed at least to at least a few key Institutes outside Indonesia. Others can write to either Ir. Rubardi, or Ir. K. Sumarno, Forest Research & Development

The future of forests and orangutans (Pongo abelii) in Sumatra: predicting impacts of oil palm plantations, road construction, and mechanisms for reducing carbon emissions from deforestation

Science.gov (United States)

Gaveau, David L. A.; Wich, Serge; Epting, Justin; Juhn, Daniel; Kanninen, Markku; Leader-Williams, Nigel

2009-09-01

Payments for reduced carbon emissions from deforestation (RED) are now attracting attention as a way to halt tropical deforestation. Northern Sumatra comprises an area of 65 000 km2 that is both the site of Indonesia's first planned RED initiative, and the stronghold of 92% of remaining Sumatran orangutans. Under current plans, this RED initiative will be implemented in a defined geographic area, essentially a newly established, 7500 km2 protected area (PA) comprising mostly upland forest, where guards will be recruited to enforce forest protection. Meanwhile, new roads are currently under construction, while companies are converting lowland forests into oil palm plantations. This case study predicts the effectiveness of RED in reducing deforestation and conserving orangutans for two distinct scenarios: the current plan of implementing RED within the specific boundary of a new upland PA, and an alternative scenario of implementing RED across landscapes outside PAs. Our satellite-based spatially explicit deforestation model predicts that 1313 km2 of forest would be saved from deforestation by 2030, while forest cover present in 2006 would shrink by 22% (7913 km2) across landscapes outside PAs if RED were only to be implemented in the upland PA. Meanwhile, orangutan habitat would reduce by 16% (1137 km2), resulting in the conservative loss of 1384 orangutans, or 25% of the current total population with or without RED intervention. By contrast, an estimated 7824 km2 of forest could be saved from deforestation, with maximum benefit for orangutan conservation, if RED were to be implemented across all remaining forest landscapes outside PAs. Here, RED payments would compensate land users for their opportunity costs in not converting unprotected forests into oil palm, while the construction of new roads to service the marketing of oil palm would be halted. Our predictions suggest that Indonesia's first RED initiative in an upland PA may not significantly reduce

The future of forests and orangutans (Pongo abelii) in Sumatra: predicting impacts of oil palm plantations, road construction, and mechanisms for reducing carbon emissions from deforestation

International Nuclear Information System (INIS)

Gaveau, David L A; Leader-Williams, Nigel; Wich, Serge; Epting, Justin; Juhn, Daniel; Kanninen, Markku

2009-01-01

Payments for reduced carbon emissions from deforestation (RED) are now attracting attention as a way to halt tropical deforestation. Northern Sumatra comprises an area of 65 000 km 2 that is both the site of Indonesia's first planned RED initiative, and the stronghold of 92% of remaining Sumatran orangutans. Under current plans, this RED initiative will be implemented in a defined geographic area, essentially a newly established, 7500 km 2 protected area (PA) comprising mostly upland forest, where guards will be recruited to enforce forest protection. Meanwhile, new roads are currently under construction, while companies are converting lowland forests into oil palm plantations. This case study predicts the effectiveness of RED in reducing deforestation and conserving orangutans for two distinct scenarios: the current plan of implementing RED within the specific boundary of a new upland PA, and an alternative scenario of implementing RED across landscapes outside PAs. Our satellite-based spatially explicit deforestation model predicts that 1313 km 2 of forest would be saved from deforestation by 2030, while forest cover present in 2006 would shrink by 22% (7913 km 2 ) across landscapes outside PAs if RED were only to be implemented in the upland PA. Meanwhile, orangutan habitat would reduce by 16% (1137 km 2 ), resulting in the conservative loss of 1384 orangutans, or 25% of the current total population with or without RED intervention. By contrast, an estimated 7824 km 2 of forest could be saved from deforestation, with maximum benefit for orangutan conservation, if RED were to be implemented across all remaining forest landscapes outside PAs. Here, RED payments would compensate land users for their opportunity costs in not converting unprotected forests into oil palm, while the construction of new roads to service the marketing of oil palm would be halted. Our predictions suggest that Indonesia's first RED initiative in an upland PA may not significantly reduce

Spatial and Temporal Habitat Use of an Asian Elephant in Sumatra

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Todd K. Fuller

2013-07-01

Full Text Available Increasingly, habitat fragmentation caused by agricultural and human development has forced Sumatran elephants into relatively small areas, but there is little information on how elephants use these areas and thus, how habitats can be managed to sustain elephants in the future. Using a Global Positioning System (GPS collar and a land cover map developed from TM imagery, we identified the habitats used by a wild adult female elephant (Elephas maximus sumatranus in the Seblat Elephant Conservation Center, Bengkulu Province, Sumatra during 2007–2008. The marked elephant (and presumably her 40–60 herd mates used a home range that contained more than expected medium canopy and open canopy land cover. Further, within the home range, closed canopy forests were used more during the day than at night. When elephants were in closed canopy forests they were most often near the forest edge vs. in the forest interior. Effective elephant conservation strategies in Sumatra need to focus on forest restoration of cleared areas and providing a forest matrix that includes various canopy types.

Is Interseismic Deformation along the Sumatra Subduction Zone Ever 'Stable'?

Science.gov (United States)

Hill, E.; Meltzner, A. J.; Moore, J. D. P.; Philibosian, B.; Feng, L.; Lindsey, E. O.; Bradley, K. E.; Qiu, Q.

2017-12-01

Estimates of megathrust coupling ratios are regularly calculated using geodetic data then used to forecast seismic and tsunami hazard. Given that the geodetic data capture only a small snapshot in time, an important question is the extent to which these accurately reflect long-term strain build up. We analyze this question using the Sumatra subduction zone as a case study. Here we have 15 years of continuous GPS data, with some collected before the recent great earthquake sequence started in 2004, and most collected afterwards. We also have paleogeodetic data from coral microatolls dating back over many earthquake supercycles (sequences of great earthquakes that are clustered in time). The coral data indicate significant changes in interseismic deformation rates over time for the Sunda megathrust; these could result from spontaneous changes in the spatial distribution of megathrust locking, from coseismically induced changes in locking, or from long-term viscoelastic processes. One question we ask is whether in Sumatra a transient rheology with high steady-state viscoelastic relaxation times, coupled with a relatively short recurrence interval for the supercycles (as little as 200 years), results in a situation where interseismic rates evolve throughout the entire earthquake cycle. To illustrate, a GPS station in northern Sumatra has been rapidly uplifting since 2004 at rates of 3 cm/yr; we do not know when this will slow down, but if this is a small piece of a viscoelastic decay curve it seems likely that the relaxation time is very long, and a geodetic snapshot at any point in many decades to come will not be representative of long-term average rates. We also consider whether there is a fundamental difference between viscoelastic behavior for megathrusts and strike-slip faults, with the former driving much longer, broader-scale deformation patterns that have more influence over the interseismic period. Indeed, the nearby strike-slip Sumatran Fault does appear to

Perjanjian Bangun Guna Serah (Build, Operate And Transfer) antara Pemerintah Provinsi Sumatera Selatan dengan Pihak Swasta

OpenAIRE

Justisia, Vita

2015-01-01

Abstract: The availability of adequate infrastructure, need tosupport the implementation of national development and toimprove Indonesia's competitiveness in the global era. Toovercome this, the Government of South Sumatra Province tobuild agreement Build, Operate, and Transfer in thedevelopment of infrastructure without burdening the localbudget through cooperation with Third Parties. This article willbe assessed on what consideration the Government of SouthSumatra Province in determining sy...

FY 1999 report on the survey of the overseas geological structure, etc. Japan-Indonesia joint Tanjung Enim coal exploration project; 1999 nendo kaigai chishitsu kozo nado chosa hokokusho. Nippon Indonesia sekitan kyodo tansa Tanjung Enim project

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-03-01

The paper summed up the FY 1999 results of the survey conducted based on the agreement on the Tanjung Enim IV coal exploration project which was concluded between NEDO and Indonesia's Ministry of Mining Energy. The survey was made for an area of approximately 40km{sup 2} which is a north block of the south Arahan region, Tanjung Enim, South Sumatra, Indonesia. To grasp the succession of strata/rock facies/geological structure and the state of existence of the coal seams to be drilled, surveys were conducted on ground surface and boreholes. A total of 10 holes was test-drilled, and all the boreholes were physically logged. As a result of the survey, each of A1, A2, B, C and E coal seams was confirmed as main seams. A1, A2 and B seams are low in ash and sulfur contents with heating values of approximately 4,800 kcal/kg, C seam is high in sulfur content, and E seam is high in heating value, 6,000 kcal/kg. As coal seams for open pit mining, existence of A, B and C seams is expected which lay in the shallow part from ground surface to sea level of 0m and in the range of depth of approximately 100m. The proved coal reserves of these coals were estimated at 189 million tons. (NEDO)

GENETIC DIFFERENTIATION AMONG POPULATIONS OF Chromobotia macracanthus BLEEKER FROM SUMATRA AND KALIMANTAN BASED ON SEQUENCING GENE OF MTDNA CYTOCHROME B AND NUCLEUS DNA RAG2

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Sudarto Sudarto

2008-12-01

Full Text Available Research on genetic differentiation among populations of Chromobotia macracanthus Bleeker from Sumatra, based on sequencing gene of mtDNA Cytochrome b and nucleus DNA RAG2 has been done. The objectives of the study were to obtain the representation of genetic differentiation among population of clown loach fishes or botia (Chromobotia macracanthus from Sumatra and Kalimantan and to estimate the time divergence of both population group of botia. Samples of botia population were taken from 3 rivers in Sumatra namely Batanghari, Musi, and Tulang Bawang and one river from Kalimantan namely Kapuas. The genetic analysis was based on the sequencing of mtDNA Cytochrome b and nucleus DNA RAG2. The statistical analysis was done by using APE package on R language. The parameters observed were: nucleotide diversity, genetic distance, and neighbor-joining tree. The result showed that the highest nucleotide diversity was fish population of Musi, while the other two populations, Tulang Bawang (Sumatra and Kapuas (Kalimantan, were considered as the lowest genetic diversity especially based on nucleus DNA RAG2 sequencing. Based on mtDNA Cytochrome-b sequencing, the most distinct population among those populations based on genetic distance were fish populations of Musi and Kapuas. According to the result of neighbor-joining tree analysis, the populations of botia were classified into two groups namely group of Sumatra and group of Kalimantan. The estimation of time divergence among group of population of Sumatra and Kalimantan based on mtDNA Cytochrome b was about 9.25—9.46 million years (Miocene era. The high genetic differences between groups of Sumatra and Kalimantan suggested that the effort of restocking botia from Sumatra into Kalimantan has to be done carefully, because it may disturb the gene originality of both botia populations.

Acetylcholinesterase Inhibitors (AChEI's for the treatment of visual hallucinations in schizophrenia: A review of the literature

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Patel Sachin S

2010-09-01

Full Text Available Abstract Background Visual hallucinations occur in various neurological diseases, but are most prominent in Lewy body dementia, Parkinson's disease and schizophrenia. The lifetime prevalence of visual hallucinations in patients with schizophrenia is much more common than conventionally thought and ranges from 24% to 72%. Cortical acetylcholine (ACh depletion has been associated with visual hallucinations; the level of depletion being related directly to the severity of the symptoms. Current understanding of neurobiological visual processing and research in diseases with reduced cholinergic function, suggests that AChEI's may prove beneficial in treating visual hallucinations. This offers the potential for targeted drug therapy of clinically symptomatic visual hallucinations in patients with schizophrenia using acetylcholinesterase inhibition. Methods A systematic review was carried out investigating the evidence for the effects of AChEI's in treating visual hallucinations in Schizophrenia. Results No evidence was found relating to the specific role of AChEI's in treating visual hallucinations in this patient group. Discussion Given the use of AChEI's in targeted, symptom specific treatment in other neuropsychiatric disorders, it is surprising to find no related literature in schizophrenia patients. The use of AChEI's in schizophrenia has investigated effects on cognition primarily with non cognitive effects measured more broadly. Conclusions We would suggest that more focused research into the effects of AChEI's on positive symptoms of schizophrenia, specifically visual hallucinations, is needed.

Imaging of 3-D seismic velocity structure of Southern Sumatra region using double difference tomographic method

Energy Technology Data Exchange (ETDEWEB)

Lestari, Titik, E-mail: t2klestari@gmail.com [Meteorological Climatological and Geophysical Agency (MCGA), Jalan Angkasa I No.2 Kemayoran, Jakarta Pusat, 10720 (Indonesia); Faculty of Earth Science and Technology, Bandung Institute of Technology, Jalan Ganesa No.10, Bandung 40132 (Indonesia); Nugraha, Andri Dian, E-mail: nugraha@gf.itb.ac.id [Global Geophysical Research Group, Faculty of Mining and Petroleum Engineering, Bandung Institute of Technology, Jalan Ganesa 10 Bandung 40132 (Indonesia)

2015-04-24

Southern Sumatra region has a high level of seismicity due to the influence of the subduction system, Sumatra fault, Mentawai fault and stretching zone activities. The seismic activities of Southern Sumatra region are recorded by Meteorological Climatological and Geophysical Agency (MCGA’s) Seismograph network. In this study, we used earthquake data catalog compiled by MCGA for 3013 events from 10 seismic stations around Southern Sumatra region for time periods of April 2009 – April 2014 in order to invert for the 3-D seismic velocities structure (Vp, Vs, and Vp/Vs ratio). We applied double-difference seismic tomography method (tomoDD) to determine Vp, Vs and Vp/Vs ratio with hypocenter adjustment. For the inversion procedure, we started from the initial 1-D seismic velocity model of AK135 and constant Vp/Vs of 1.73. The synthetic travel time from source to receiver was calculated using ray pseudo-bending technique, while the main tomographic inversion was applied using LSQR method. The resolution model was evaluated using checkerboard test and Derivative Weigh Sum (DWS). Our preliminary results show low Vp and Vs anomalies region along Bukit Barisan which is may be associated with weak zone of Sumatran fault and migration of partial melted material. Low velocity anomalies at 30-50 km depth in the fore arc region may indicated the hydrous material circulation because the slab dehydration. We detected low seismic seismicity in the fore arc region that may be indicated as seismic gap. It is coincides contact zone of high and low velocity anomalies. And two large earthquakes (Jambi and Mentawai) also occurred at the contact of contrast velocity.

Analysis of Seismotektonic Patterns in Sumatra Region Based on the Focal Mechanism of Earthquake Period 1976-2016

Science.gov (United States)

Indah, F. P.; Syafriani, S.; Andiyansyah, Z. S.

2018-04-01

Sumatra is in an active subduction zone between the indo-australian plate and the eurasian plate and is located at a fault along the sumatra fault so that sumatra is vulnerable to earthquakes. One of the ways to find out the cause of earthquake can be done by identifying the type of earthquake-causing faults based on earthquake of focal mechanism. The data used to identify the type of fault cause of earthquake is the earth tensor moment data which is sourced from global cmt period 1976-2016. The data used in this research using magnitude m ≥ 6 sr. This research uses gmt software (generic mapping tolls) to describe the form of fault. From the research result, it is found that the characteristics of fault field that formed in every region in sumatera island based on data processing and data of earthquake history of 1976-2016 period that the type of fault in sumatera fault is strike slip, fault type in mentawai fault is reverse fault (rising faults) and dip-slip, while the fault type in the subduction zone is dip-slip.

Contribution of Forest Restoration to Rural Livelihoods and Household Income in Indonesia

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Nayu Nuringdati Widianingsih

2016-08-01

Full Text Available Forest resources remain vital to the survival of many rural communities, though the level of forest reliance varies across a range of sites and socio-economic settings. This article investigates variation in forest utilization across households in three ethnic groups living near a forest restoration area in Sumatra, Indonesia. Survey data were collected on 268 households, with a four-month recall period and three repeat visits to each selected household within a year. Random sampling was applied to select households in five villages and five Batin Sembilan (indigenous semi-nomadic groups. Sampled households belonged to three ethnic groups: 15% were Batin Sembilan, 40% Local Malayan, and 45% Immigrant households. Indigenous households displayed the highest reliance on forests: 36% of their annual total income came from this source, as compared with 10% and 8% for Local and Immigrant households, respectively. Our findings showed that the livelihoods of indigenous groups were still intricately linked with forest resources, despite a rapid landscape-wide transition from natural forest to oil palm and timber plantations.

Preparation and comparison of a-C:H coatings using reactive sputter techniques

Energy Technology Data Exchange (ETDEWEB)

Keunecke, M., E-mail: martin.keunecke@ist.fraunhofer.d [Fraunhofer Institute for Surface Engineering and Thin Films (IST), Braunschweig (Germany); Weigel, K.; Bewilogua, K. [Fraunhofer Institute for Surface Engineering and Thin Films (IST), Braunschweig (Germany); Cremer, R.; Fuss, H.-G. [CemeCon AG, Wuerselen (Germany)

2009-12-31

Amorphous hydrogenated carbon (a-C:H) coatings are widely used in several industrial applications. These coatings commonly will be prepared by plasma activated chemical vapor deposition (PACVD). The main method used to prepare a-C:H coating in industrial scale is based on a glow discharge in a hydrocarbon gas like acetylene or methane using a substrate electrode powered with medium frequency (m.f. - some 10 to 300 kHz). Some aims of further development are adhesion improvement, increase of hardness and high coating quality on complex geometries. A relatively new and promising technique to fulfil these requirements is the deposition of a-C:H coatings by a reactive d.c. magnetron sputter deposition from a graphite target with acetylene as reactive gas. An advancement of this technique is the deposition in a pulsed magnetron sputter process. Using these three mentioned techniques a-C:H coatings were prepared in the same deposition machine. For adhesion improvement different interlayer systems were applied. The effect of different substrate bias voltages (d.c. and d.c. pulse) was investigated. By applying the magnetron sputter technique in the d.c. pulse mode, plastic hardness values up to 40 GPa could be reached. Besides hardness other mechanical properties like resistance against abrasive wear were measured and compared. Cross sectional SEM images showed the growth structure of the coatings.

Capacity Development and Strengthening for Energy Policy formulation and implementation of Sustainable Energy Projects in Indonesia CASINDO. Deliverable No. 14. Fast-track program at UNDIP and UNCEN

Energy Technology Data Exchange (ETDEWEB)

Wijnker, M. (ed.) [Eindhoven University of Technology TUE, Eindhoven (Netherlands)

2011-01-15

The overall objective of the CASINDO programme is to establish a self-sustaining and self-developing structure at both the national and regional level to build and strengthen human capacity to enable the provinces of North Sumatra, Yogyakarta, Central Java, West Nusa Tenggara and Papua to formulate sound policies for renewable energy and energy efficiency and to develop and implement sustainable energy projects. The relationship between UNDIP (Diponegoro University in Semarang, Java, Indonesia) and TU/e (Eindhoven University of Technology) has improved because of organising two additional activities together. The chosen topics of the two workshops offered a good opportunity to get to know each other. The level of knowledge in sustainable energy and energy efficiency at UNDIP is already on a high level. The relationship between UNCEN (Cenderawasih University, Jayapura, Papua, Indonesia) and TU/e has also improved much through the organisation of two additional activities. Staff of UNCEN took the opportunity to organise two workshops improving their knowledge in the field of sustainable energy and energy efficiency.

The 2004 Sumatra Earthquake Mw 9.3: Seismological and Geophysical Investigations in the Andaman-Nicobar Islands

Science.gov (United States)

Mooney, W. D.; Kayal, J.

2007-05-01

The December 26, 2004 Sumatra-Andaman earthquake (MW 9.3) is the fourth largest event (M>9.0) in the world during the last 100 years. It occurred by thrust faulting on the interplate thrust zone of the subducting India plate and overriding Burma platelet. The main shock rupture, ~1300 km long and ~200 km wide, propagated from north of Sumatra to Andaman - Nicobar Islands; the slow rupture generated Tsunami which killed about 300,000 people. The epicenter of the earthquake is located at 3.90N and 94.260E with a focal depth at 28 km (USGS). This mega seismic event triggered giant tsunamis that devastated the coastal regions of Indonesia, Malaysia, Thailand, Sri Lanka, India, Maldives and even the east coast of Africa. The impact of the tsunami was quite severe in India, in the coasts of Andaman and Nicobar Islands. The Air-base in the Car- Nicobar island was totally devastated by the tsunami and killed about 200 people. Macroseismic survey was carried out by different teams of GSI in North Andaman, Middle Andaman, South Andaman, Havelock Hut Bay and also in the Nicobar Islands. A maximum intensity VIII was recorded in the Andaman Islands. The mega thrust event was followed by an intense aftershock activity spreading over an area extending between 30-140N along the Andaman - Nicobar - Sumatra Island arc region. The aftershocks are distributed northwards from the epicenter of the main shock suggesting a unilateral rupture propagation. The aftershock (M >4.5) area covers a length of about 1300 km and a width of about 200 km, in a 'banana' shape. The national network (IMD) recorded almost all aftershocks M >5.0; about 350 were recorded till 31.01.2005. The Geological Survey of India (GSI) deployed six temporary seismograph stations in the Andaman and Nicobar Islands and also in Havelok and Narkunda (volcanic) islands. About 20,000 aftershocks (M >3.0) were recorded until end of March, 2005. About 1000 aftershocks (M >3.0) located by the GSI network until January 31, 2005

Neonikotinoid İnsektisitlere Bağlı Olarak Drosophila melanogaster’in AChE Aktivitesinde Meydana Gelen Değişikliklerin Bitkisel Ekstraktlar ile Giderilmesi Üzerine Araştırmalar

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Sedat Ünver

2014-12-01

Full Text Available Bu çalışmada, Drosophila melanogaster’in ergin bireylerinde bulunan asetil kolinesteraz (AChE enzim aktivitesi üzerine İmidakloprid (İMİ ve Asetamiprid (ASE  insektisitlerinin etkileri araştırılmıştır. Ayrıca farklı bitkilere ait su ekstraktlarının (Salvia lavandulifolia, Hypericum scabrum, Capsella bursa-pastoris ve Teucrium orientale iyileştirici etkileri de in vivo olarak incelenmiştir. Bu amaçla iki deney grubu oluşturulmuştur. İlk deney grubunda ergin bireylere yalnızca farklı dozlarda insektisit (0,5; 1,0; 1,5 ve 2,0 ppm, diğer deney grubunda ise insektisit + bitki ekstraktları (1:1 v/v birlikte uygulanmıştır. Uygulamalar sonucunda insektisitler doz artışına bağlı olarak ergin bireylerde AChE aktivitesini artırmıştır (P<0,05. Ancak insektisitler bitkisel ekstraktlar ile birlikte uygulanınca enzim aktivitesi tekrar kontrol grubuna yaklaşmıştır (P<0,05.

Kajian Tvc Wonderful Indonesia sebagai Cermin Citra Indonesia di Mata Dunia

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Angela Oscario

2013-10-01

Full Text Available Tourism is one of the most important sectors supporting the economy of Indonesia. One way to develop the Indonesian tourism is strengthening the image of Indonesia in the world. To strengthen the image, Indonesia has replaced the old brand, “Visit Indonesia”, and launched a new brand, “Wonderful Indonesia”. Besides the logo, in order to campaign “Wonderful Indonesia,” some television commercials have been launched. An advertising, which creates a powerful image, not only has a great power to influence the viewers but can also be a double-edged sword. Advertising can become a mirror of reality, but it can also become a distorted mirror of reality. A similar case happens with Wonderful Indonesia television commercial, which was released early in 2012 by the Ministry of Tourism and Creative Economy. The television commercial is considered to have distorted the image of Indonesia in the world by displaying only the culture, society, and nature of Java and Bali. Meanwhile, the other Wonderful Indonesia television commercial, “Feeling is Believing,” which was launched by Indonesia Tourism Board in 2012 considered to have become quite successful framing the beauty, and diversity of the cultures, communities, regions, and natures of Indonesia. Learning from the mistakes, and considering the importance of an image, the future Wonderful Indonesia television commercial should be dealt more carefully. The image that is proper to represent Indonesia, the visual signifier should reflect the intended signified precisely.  

Orangutans, enamel defects, and developmental health: A comparison of Borneo and Sumatra.

Science.gov (United States)

Skinner, Mark F; Skinner, Matthew M

2017-08-01

Orangutans (Pongo sp.) show among the highest occurrence of three types of developmental enamel defect. Two are attributed to nutritional factors that reduce bone growth in the infant's face early in development. Their timing and prevalence indicate that Sumatra provides a better habitat than does Borneo. The third type, repetitive linear enamel hypoplasia (rLEH) is very common but its etiology is not understood. Our objective is to draw attention to this enigmatic, episodic stressor in the lives of orangutans. We are concerned that neglect of this possible marker of ill health may be contributing, through inaction, to their alarming decline in numbers. Width and depth of an LEH are considered proxies for duration and intensity of stress. The hypothesis that Bornean orangutans would exhibit relatively wider and deeper LEH was tested on 163 independent episodes of LEH from 9 Sumatran and 26 Bornean orangutans measured with a NanoFocus AG "µsurf Mobile Plus" scanner. Non-normally distributed data (depths) were converted to natural logs. No difference was found in width of LEH among the two island taxa; nor are their differences in width or depth between the sexes. After controlling for significant differences in LEH depths between incisors and canines, defects are, contrary to prediction, significantly deeper in Sumatran than Bornean animals (median = 28, 18 µm, respectively). It is concluded that repetitive LEH records an unknown but significant stressor present in both Sumatra and Borneo, with an average periodicity of 6 months (or multiples thereof) that lasts about 6-8 weeks. It is worse in Sumatra. Given this patterning, shared with apes from a wide range of ecological and temporal sources, rLEH is more likely attributable to disease than to malnutrition. © 2017 Wiley Periodicals, Inc.

Fiscal 2000 survey report on overseas geological structure, etc. Project for exchanging experts - Exploration technology (Indonesia); 2000 nendo kaigai chishitsu kozo to chosa hokokusho. Gijutsusha koryu jigyo - Tansa gijutsu bunya (Indonesia)

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-03-01

For the stabilization of coal supply/demand in the APEC (Asia-Pacific Economic Cooperation Conference) region and for the stable supply of coal to Japan, Japanese engineers and experts were dispatched to Indonesia, where coal production was remarkably increasing and efforts were being actively exerted to develop new coal mining fields, for training Indonesian specialists there, and Indonesian specialists were invited to Japan for training here. Japanese instructors on dispatch delivered lectures on coal geology, exploration, and exploitation at the human resource development center of Bandung City during the period July 20 through August 4, 2000, which was followed by a coal outcrop survey training session in the field. The trainees were from Kalimantan, Sumatra, Java, etc., and numbered 30. The trainees invited to Japan received lectures and training related to coal geology, exploration, and mining programs during the period October 19 through November 18, 2000, at the Geological Survey of Japan, Agency of Industrial Science and Technology, Ministry of International Trade and Industry; Matsushima Coal Mining Co., Ltd.; Enzan Plant, Tone Corporation; DIA Consultants Co., Ltd.; and Mitsubishi Materials Corporation. (NEDO)

The current agonists and positive allosteric modulators of α7 nAChR for CNS indications in clinical trials

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Taoyi Yang

2017-11-01

Full Text Available The alpha-7 nicotinic acetylcholine receptor (α7 nAChR, consisting of homomeric α7 subunits, is a ligand-gated Ca2+-permeable ion channel implicated in cognition and neuropsychiatric disorders. Enhancement of α7 nAChR function is considered to be a potential therapeutic strategy aiming at ameliorating cognitive deficits of neuropsychiatric disorders such as Alzheimer's disease (AD and schizophrenia. Currently, a number of α7 nAChR modulators have been reported and several of them have advanced into clinical trials. In this brief review, we outline recent progress made in understanding the role of the α7 nAChR in multiple neuropsychiatric disorders and the pharmacological effects of α7 nAChR modulators used in clinical trials.

α7-nAChR Knockout Mice Decreases Biliary Hyperplasia and Liver Fibrosis in Cholestatic Bile-Duct Ligated Mice.

Science.gov (United States)

Ehrlich, Laurent; O'Brien, April; Hall, Chad; White, Tori; Chen, Lixian; Wu, Nan; Venter, Julie; Scrushy, Marinda; Mubarak, Muhammad; Meng, Fanyin; Dostal, David; Wu, Chaodong; Lairmore, Terry C; Alpini, Gianfranco; Glaser, Shannon

2018-03-26

α7-nAChR is a nicotinic acetylcholine receptor (specifically expressed on hepatic stellate cells, Kupffer cells, and cholangiocytes) that regulates inflammation and apoptosis in the liver. Thus, targeting α7-nAChR may be therapeutic in biliary diseases. Bile-duct ligation (BDL) was performed on wild-type (WT) and α7-nAChR-/- mice. We first evaluated the expression of α7-nAChR by immunohistochemistry (IHC) in liver sections. IHC was also performed to assess intrahepatic bile-duct mass (IBDM), and Sirius Red staining was performed to quantify the amount of collagen deposition. Immunofluorescence was performed to assess co-localization of α7-nAChR with bile ducts (co-stained with CK-19) and hepatic stellate cells (HSCs) (co-stained with desmin). The mRNA expression of α7-nAChR, Ki67/PCNA (proliferation), fibrosis genes (TGF-β1, Fibronectin-1, Col1α1, and α-SMA), and inflammatory markers (IL-6, IL-1β, and TNFα) was measured by real-time PCR. Biliary TGF-β1 and hepatic CD68 (Kupffer cell marker) expression was assessed using IHC. α7-nAChR immunoreactivity was observed in both bile ducts and HSCs and increased following BDL. α7-nAChR-/- BDL mice exhibited decreased: (i) bile duct mass, liver fibrosis, and inflammation; and (ii) immunoreactivity of TGF-1 as well as expression of fibrosis genes compared to WT BDL mice. α7-nAChR activation triggers biliary proliferation and liver fibrosis and may be a therapeutic target in managing extra-hepatic biliary obstruction.

Differential Cytokine Changes in Patients with Myasthenia Gravis with Antibodies against AChR and MuSK.

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Vuslat Yilmaz

Full Text Available Neuromuscular transmission failure in myasthenia gravis (MG is most commonly elicited by autoantibodies (ab to the acetylcholine receptor or the muscle-specific kinase, constituting AChR-MG and MuSK-MG. It is controversial whether these MG subtypes arise through different T helper (Th 1, Th2 or Th17 polarized immune reactions and how these reactions are blunted by immunosuppression. To address these questions, plasma levels of cytokines related to various Th subtypes were determined in patients with AChR-MG, MuSK-MG and healthy controls (CON. Peripheral blood mononuclear cells (PBMC were activated in vitro by anti-CD3, and cytokines were quantified in supernatants. In purified blood CD4+ T cells, RNA of various cytokines, Th subtype specific transcription factors and the co-stimulatory molecule, CD40L, were quantified by qRT-PCR. Plasma levels of Th1, Th2 and Th17 related cytokines were overall not significantly different between MG subtypes and CON. By contrast, in vitro stimulated PBMC from MuSK-MG but not AChR-MG patients showed significantly increased secretion of the Th1, Th17 and T follicular helper cell related cytokines, IFN-γ, IL-17A and IL-21. Stimulated expression of IL-4, IL-6, IL-10 and IL-13 was not significantly different. At the RNA level, expression of CD40L by CD4+ T cells was reduced in both AChR-MG and MuSK-MG patients while expression of Th subset related cytokines and transcription factors were normal. Immunosuppression treatment had two effects: First, it reduced levels of IL12p40 in the plasma of AChR-MG and MuSK-MG patients, leaving other cytokine levels unchanged; second, it reduced spontaneous secretion of IFN-γ and increased secretion of IL-6 and IL-10 by cultured PBMC from AChR-MG, but not MuSK-MG patients. We conclude that Th1 and Th17 immune reactions play a role in MuSK-MG. Immunosuppression attenuates the Th1 response in AChR-MG and MuSK-MG, but otherwise modulates immune responses in AChR-MG and Mu

An Analysis Of Manufacturing Market Structure In North Sumatra Province

OpenAIRE

Rasidin Karo-Karo Sitepu; Muhammad Asaad

2011-01-01

This study aims to analyze market structure and manufacturing industry performance on the economy of North Sumatra. The analysis uses two approaches, namely SCP analysis and econometric model. The data used is the Survey of Large Medium 2005-2009. The result shows that the structure of the industry is more dominant, including tight oligopoly, only small parts which belong to loose oligopoly and oligopoly markets. Some industries which have important roles for the economy are the palm oil indu...

Religion, class and schooled sexuality among Minangkabau teenage girls

OpenAIRE

Lyn Parker

2009-01-01

This paper examines the meanings attached to sexuality and femininity by Minangkabau teenage girls in schools in West Sumatra, Indonesia. Schools in West Sumatra communicate a hegemonic, normative understanding of womanhood, and a moral consciousness of the female sexual body, to students. Different types of schools – academic, vocational and Islamic senior high schools – have a different ‘curriculum of the body’ (Lesko 1988) and differently discipline bodies and shape sexuality. School girls...

Reciprocal activation of α5-nAChR and STAT3 in nicotine-induced human lung cancer cell proliferation.

Science.gov (United States)

Zhang, Yao; Jia, Yanfei; Li, Ping; Li, Huanjie; Xiao, Dongjie; Wang, Yunshan; Ma, Xiaoli

2017-07-20

Cigarette smoking is the top environmental risk factor for lung cancer. Nicotine, the addictive component of cigarettes, induces lung cancer cell proliferation, invasion and migration via the activation of nicotinic acetylcholine receptors (nAChRs). Genome-wide association studies (GWAS) show that CHRNA5 gene encoding α5-nAChR is especially relevant to lung cancer. However, the mechanism of this subunit in lung cancer is not clear. In the present study, we demonstrate that the expression of α5-nAChR is correlated with phosphorylated STAT3 (pSTAT3) expression, smoking history and lower survival of non-small cell lung cancer (NSCLC) samples. Nicotine increased the levels of α5-nAChR mRNA and protein in NSCLC cell lines and activated the JAK2/STAT3 signaling cascade. Nicotine-induced activation of JAK2/STAT3 signaling was inhibited by the silencing of α5-nAChR. Characterization of the CHRNA5 promoter revealed four STAT3-response elements. ChIP assays confirmed that the CHRNA5 promoter contains STAT3 binding sites. By silencing STAT3 expression, nicotine-induced upregulation of α5-nAChR was suppressed. Downregulation of α5-nAChR and/or STAT3 expression inhibited nicotine-induced lung cancer cell proliferation. These results suggest that there is a feedback loop between α5-nAChR and STAT3 that contributes to the nicotine-induced tumor cell proliferation, which indicates that α5-nAChR is an important therapeutic target involved in tobacco-associated lung carcinogenesis. Copyright © 2017 Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, and Genetics Society of China. Published by Elsevier Ltd. All rights reserved.

Quantifying above- and belowground biomass carbon loss with forest conversion in tropical lowlands of Sumatra (Indonesia).

Science.gov (United States)

Kotowska, Martyna M; Leuschner, Christoph; Triadiati, Triadiati; Meriem, Selis; Hertel, Dietrich

2015-10-01

Natural forests in South-East Asia have been extensively converted into other land-use systems in the past decades and still show high deforestation rates. Historically, lowland forests have been converted into rubber forests, but more recently, the dominant conversion is into oil palm plantations. While it is expected that the large-scale conversion has strong effects on the carbon cycle, detailed studies quantifying carbon pools and total net primary production (NPPtotal ) in above- and belowground tree biomass in land-use systems replacing rainforest (incl. oil palm plantations) are rare so far. We measured above- and belowground carbon pools in tree biomass together with NPPtotal in natural old-growth forests, 'jungle rubber' agroforests under natural tree cover, and rubber and oil palm monocultures in Sumatra. In total, 32 stands (eight plot replicates per land-use system) were studied in two different regions. Total tree biomass in the natural forest (mean: 384 Mg ha(-1) ) was more than two times higher than in jungle rubber stands (147 Mg ha(-1) ) and >four times higher than in monoculture rubber and oil palm plantations (78 and 50 Mg ha(-1) ). NPPtotal was higher in the natural forest (24 Mg ha(-1)  yr(-1) ) than in the rubber systems (20 and 15 Mg ha(-1)  yr(-1) ), but was highest in the oil palm system (33 Mg ha(-1)  yr(-1) ) due to very high fruit production (15-20 Mg ha(-1)  yr(-1) ). NPPtotal was dominated in all systems by aboveground production, but belowground productivity was significantly higher in the natural forest and jungle rubber than in plantations. We conclude that conversion of natural lowland forest into different agricultural systems leads to a strong reduction not only in the biomass carbon pool (up to 166 Mg C ha(-1) ) but also in carbon sequestration as carbon residence time (i.e. biomass-C:NPP-C) was 3-10 times higher in the natural forest than in rubber and oil palm plantations. © 2015 John Wiley & Sons Ltd.

Gas Chromatography, GC/Mass Analysis and Bioactivity of Essential Oil from Aerial Parts of Ferulago trifida: Antimicrobial, Antioxidant, AChE Inhibitory, General Toxicity, MTT Assay and Larvicidal Activities.

Science.gov (United States)

Tavakoli, Saeed; Vatandoost, Hassan; Zeidabadinezhad, Reza; Hajiaghaee, Reza; Hadjiakhoondi, Abbas; Abai, Mohammad Reza; Yassa, Narguess

2017-09-01

We aimed to investigate different biological properties of aerial parts essential oil of Ferulago trifida Boiss and larvicidal activity of its volatile oils from all parts of plant. Essential oil was prepared by steam distillation and analyzed by Gas chromatography and GC/Mass. Antioxidant, antimicrobial, cytotoxic effects and AChE inhibitory of the oil were investigated using DPPH, disk diffusion method, MTT assay and Ellman methods. Larvicidal activity of F. trifida essential oil against malaria vector Anopheles stephensi was carried out according to the method described by WHO. In GC and GC/MS analysis, 58 compounds were identified in the aerial parts essential oil, of which E-verbenol (9.66%), isobutyl acetate (25.73%) and E-β-caryophyllene (8.68%) were main compounds. The oil showed (IC 50 = 111.2μg/ml) in DPPH and IC 50 = 21.5 mg/ml in the investigation of AChE inhibitory. Furthermore, the oil demonstrated toxicity with (LD 50 = 1.1μg/ml) in brine shrimp lethality test and with (IC 50 = 22.0, 25.0 and 42.55 μg/ml) on three cancerous cell lines (MCF-7, A-549 and HT-29) respectively. LC 50 of stem, root, aerial parts, fruits, and flowers essential oils against larvae of An. stephensi were equal with 10.46, 22.27, 20.50, 31.93 and 79.87ppm respectively. In antimicrobial activities, essential oil was effective on all specimens except Escherichia coli , Aspergillus niger and Candida albicans. The essential oil showed moderate antioxidant activity, strong antimicrobial properties and good toxic effect in brine shrimp test and MTT assay on three cancerous cell lines.

Long-term seismic observations along Myanmar-Sunda subduction margin: insights for 2004 M w > 9.0 earthquake

Science.gov (United States)

Khan, Prosanta Kumar; Banerjee, Jayashree; Shamim, Sk; Mohanty, Manoranjan

2018-03-01

The present study investigates the temporal variation of few seismic parameters between the Myanmar (Zone I), Andaman-Nicobar-Northwest Sumatra (Zone II), Southeast Sumatra-West Indonesia (Zone III) and East Indonesia (Zone IV) converging boundaries in reference to the generation of 26 December 2004 M w > 9.0 off-Sumatra mega-earthquake event. The four segments are distinguished based on tectonics parameters, distinct geological locations, great earthquake occurrences, and the Wadati-Benioff zone characteristics. Two important seismic parameters such as seismic energy and b values are computed over a time-window of 6-month period during the entire 1976-2013 period for these segments. The b values show a constant decrease in Zones II, III, and IV, whereas the Zone I does not show any such pattern prior to the 2004 mega-event. The release of seismic energy was also gradually decreasing in Zones II and III till the 2004 event, and little similar pattern was also noted in Zone IV. This distinct observation might be indicating that the stress accumulation was dominant near the Sumatra-Java area located towards southeast of Zone II and northwest of Zone III. The released strain energy during the 2004 event was subsequently migrated towards north, rupturing 1300 km of the boundary between the Northwest Sumatra and the North Andaman. The occurrence of 2004 mega-event was apparently concealed behind the long-term seismic quiescence existing near the Sumatra and Nicobar margin. A systematic study of the patterns of seismic energy release and b values, and the long-term observation of collective behaviour of the margin tectonics might have had given clues to the possibility of the 2004 mega-event.

Site Response Analysis Using DeepSoil: Case Study of Bangka Site, Indonesia

Energy Technology Data Exchange (ETDEWEB)

Iswanto, Eko Rudi; Yee, Eric [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

2015-10-15

Indonesia government declared through Act No. 17 year 2007 on the National Long-Term Development Plant Year 2005-2025 and Presidential Decree No. 5 year 2006 on the National Energy Policy (Indonesia 2007; Indonesia 2006), that nuclear energy is stated as a part of the national energy system. In order to undertake the above national policy, National Nuclear Energy Agency of Indonesia, as the promotor for the utilization of nuclear energy will conduct site study, which is a part of infrastructure preparation for NPP construction. Thorough preparation and steps are needed to operate an NPP and it takes between 10 to 15 years from the preliminary study (site selection, financial study, etc.) up to project implementation (manufacturing, construction, commissioning). During project implementation, it is necessary to prepare various documents relevant for permit application such as Safety Evaluation Report for site permit, Preliminary Safety Analysis Report and Environment Impact Assessment Report for construction permit. Considering the continuously increasing electricity energy demand, it is necessary to prepare for alternative NPP sites. The safety requirements of NPP's are stringent; amongst the various requirements is the ability to safely shut down in the wake of a possible earthquake. Ground response analysis of a potential site therefore needs to be carried out, parameter that affect the resistance of an NPP to earthquakes such as peak strain profiles is analysed. The objective of this paper is to analyse the ground response of the selected site for a NPP, using The Mw 7.9 in Sikuai Island, West Sumatra on September 12, 2007 as present input motion. This analysis will be carried out using a ground response analysis program, DeepSoil. In addition to this, an attempt was made to define the site specific input motion characteristics of the selected site for use in DeepSoil (DeepSoil 5.0). A site investigation at the WB site was performed primarily on the PS

The Malaysian Orthopaedic Association humanitarian mission to Indonesia and Sri Lanka.

Science.gov (United States)

Sharaf, I; Saw, A; Hyzan, Y; Sivananthan, K S

2005-07-01

The tsunami which occurred off the west coast of North Sumatra on December 26, 2004 devastated the coastal areas of North Sumatra, South-West Thailand, South-East India and Sri Lanka killing more than a quarter of a million people. The destruction was enormous with many coastal villages destroyed. The other countries affected were Malaysia, Myanmar, Maldives, Bangladesh, Somalia, Kenya, Tanzania and the Seychelles. In January 2005, volunteers went in weekly rotation to Banda Aceh in collaboration with Global Peace Mission. These were Dr Hyzan Yusof, Dr Suryasmi Duski, Dr Sharaf Ibrahim, Dr Saw Aik, Dr Kamariah Nor and Dr Nor Azlin. In Banda Aceh, the surgical procedures that we could do were limited to external fixation of open fractures and debriding infected wounds at the Indonesian Red Crescent field hospital. In February, a team comprising Dato Dr K S Sivananthan, Dr T Kumar and Dr S Vasan spent a week in Sri Lanka. In Sri Lanka, Dato Sivananthan and his team were able to perform elective orthopaedic operations in Dr Poonambalam Memorial Hospital. We appealed for national and international aid and received support from local hospitals and the orthopaedic industry. International aid bound for Banda Aceh arrived in Kuala Lumpur from the Philippine Orthopaedic Association, the Chiba Children's Hospital in Japan and the Chinese Orthopaedic Association. The COA donated 1.5 tons of orthopaedic equipments. A special handing over ceremony from the COA to the Indonesian Orthopaedic Association was held in Putrajaya in March. Malaysia Airlines flew in the donated equipment to Kuala Lumpur while the onward flight to Aceh was provided by the Royal Malaysian Air Force. In April, Dr Saw Aik and Dr Yong Su Mei joined the Tsu-Chi International Medical Association for volunteer services on Batam Island, Indonesia. The MOA acknowledges the many individuals and organizations, both governmental and non-governmental, for their contributions in the humanitarian efforts.

Indonesia's Fires and Haze

International Development Research Centre (IDRC) Digital Library (Canada)

WWF Malaysia provided information and advice about fires and haze impacts to the government and ..... Forest management and land-use practices in Sumatra and Kalimantan have evolved very ..... In principle, the study should compare the situation with and without haze. ...... Profit before taxation is 5 per cent of turnover.

Menthol Enhances Nicotine Reward-Related Behavior by Potentiating Nicotine-Induced Changes in nAChR Function, nAChR Upregulation, and DA Neuron Excitability.

Science.gov (United States)

Henderson, Brandon J; Wall, Teagan R; Henley, Beverley M; Kim, Charlene H; McKinney, Sheri; Lester, Henry A

2017-11-01

Understanding why the quit rate among smokers of menthol cigarettes is lower than non-menthol smokers requires identifying the neurons that are altered by nicotine, menthol, and acetylcholine. Dopaminergic (DA) neurons in the ventral tegmental area (VTA) mediate the positive reinforcing effects of nicotine. Using mouse models, we show that menthol enhances nicotine-induced changes in nicotinic acetylcholine receptors (nAChRs) expressed on midbrain DA neurons. Menthol plus nicotine upregulates nAChR number and function on midbrain DA neurons more than nicotine alone. Menthol also enhances nicotine-induced changes in DA neuron excitability. In a conditioned place preference (CPP) assay, we observed that menthol plus nicotine produces greater reward-related behavior than nicotine alone. Our results connect changes in midbrain DA neurons to menthol-induced enhancements of nicotine reward-related behavior and may help explain how smokers of menthol cigarettes exhibit reduced cessation rates.

Quantifying changes in the rates of forest clearing in Indonesia from 1990 to 2005 using remotely sensed data sets

International Nuclear Information System (INIS)

Hansen, Matthew C; Potapov, Peter V; Pittman, Kyle; Stehman, Stephen V; Arunarwati, Belinda; Stolle, Fred

2009-01-01

Timely and accurate data on forest change within Indonesia is required to provide government, private and civil society interests with the information needed to improve forest management. The forest clearing rate in Indonesia is among the highest reported by the United Nations Food and Agriculture Organization (FAO), behind only Brazil in terms of forest area lost. While the rate of forest loss reported by FAO was constant from 1990 through 2005 (1.87 Mha yr -1 ), the political, economic, social and environmental drivers of forest clearing changed at the close of the last century. We employed a consistent methodology and data source to quantify forest clearing from 1990 to 2000 and from 2000 to 2005. Results show a dramatic reduction in clearing from a 1990s average of 1.78 Mha yr -1 to an average of 0.71 Mha yr -1 from 2000 to 2005. However, annual forest cover loss indicator maps reveal a near-monotonic increase in clearing from a low in 2000 to a high in 2005. Results illustrate a dramatic downturn in forest clearing at the turn of the century followed by a steady resurgence thereafter to levels estimated to exceed 1 Mha yr -1 by 2005. The lowlands of Sumatra and Kalimantan were the site of more than 70% of total forest clearing within Indonesia for both epochs; over 40% of the lowland forests of these island groups were cleared from 1990 to 2005. The method employed enables the derivation of internally consistent, national-scale changes in the rates of forest clearing, results that can inform carbon accounting programs such as the Reducing Emissions from Deforestation and Forest Degradation in Developing Countries (REDD) initiative.

The future of forests and orangutans (Pongo abelii) in Sumatra: predicting impacts of oil palm plantations, road construction, and mechanisms for reducing carbon emissions from deforestation

Energy Technology Data Exchange (ETDEWEB)

Gaveau, David L A; Leader-Williams, Nigel [Durrell Institute of Conservation and Ecology, University of Kent, Canterbury, Kent CT2 7NR (United Kingdom); Wich, Serge [Great Apes Trust of Iowa, 4200 SE 44th Avenue, Des Moines, IA 50320 (United States); Epting, Justin; Juhn, Daniel [Center for Applied Biodiversity Science, Conservation International, 2011 Crystal Drive, Suite 500, Arlington, VA 22202 (United States); Kanninen, Markku, E-mail: dgaveau@yahoo.co.u, E-mail: swich@greatapetrust.or, E-mail: justep22@myfastmail.co, E-mail: d.juhn@conservation.or, E-mail: m.kanninen@cgiar.or, E-mail: n.leader-williams@kent.ac.u [Center for International Forestry Research, Jalan CIFOR, Situ Gede, Sidang Barang, Bogor, West Java (Indonesia)

2009-09-15

Payments for reduced carbon emissions from deforestation (RED) are now attracting attention as a way to halt tropical deforestation. Northern Sumatra comprises an area of 65 000 km{sup 2} that is both the site of Indonesia's first planned RED initiative, and the stronghold of 92% of remaining Sumatran orangutans. Under current plans, this RED initiative will be implemented in a defined geographic area, essentially a newly established, 7500 km{sup 2} protected area (PA) comprising mostly upland forest, where guards will be recruited to enforce forest protection. Meanwhile, new roads are currently under construction, while companies are converting lowland forests into oil palm plantations. This case study predicts the effectiveness of RED in reducing deforestation and conserving orangutans for two distinct scenarios: the current plan of implementing RED within the specific boundary of a new upland PA, and an alternative scenario of implementing RED across landscapes outside PAs. Our satellite-based spatially explicit deforestation model predicts that 1313 km{sup 2} of forest would be saved from deforestation by 2030, while forest cover present in 2006 would shrink by 22% (7913 km{sup 2}) across landscapes outside PAs if RED were only to be implemented in the upland PA. Meanwhile, orangutan habitat would reduce by 16% (1137 km{sup 2}), resulting in the conservative loss of 1384 orangutans, or 25% of the current total population with or without RED intervention. By contrast, an estimated 7824 km{sup 2} of forest could be saved from deforestation, with maximum benefit for orangutan conservation, if RED were to be implemented across all remaining forest landscapes outside PAs. Here, RED payments would compensate land users for their opportunity costs in not converting unprotected forests into oil palm, while the construction of new roads to service the marketing of oil palm would be halted. Our predictions suggest that Indonesia's first RED initiative in an

Analysis on traditional fishing grounds in Indonesia`s Natuna waters under International Law

Science.gov (United States)

Kurniaty, R.; Ikaningtyas; Ruslijanto, P. A.

2018-04-01

This paper examines the boundary tension between Indonesia and China regarding traditional fishing ground in Natuna. Indonesia`s Natuna island is claimed by the China government as its traditional fishing zone/ground. The inclusion of Natuna territory into China`s traditional fishing zone brings new problems to Indonesia, especially with the Chinese ships docked and entered Indonesia`s exclusive economic zone, as well as several cases of illegal fishing over the territorial waters of Indonesia. Claims on traditional fishing zones have the potential to threaten the sovereignty of the Indonesian territory. This study aims to analyze the claims of the traditional fishing rights of China over the waters of the Natuna Islands under international law, especially UNCLOS 1982. This study revealed that the china`s argument of traditional fishing ground in Natuna to the nine dash line map is a unilateral claim, there is no international legal norm that can be used as the legal basis. Indonesia and some ASEAN countries have Internationally validated bilateral agreement on the continental shelf (i.e. Indonesia-Vietnam and Indonesia-Malaysia) thus the inclusion of Natuna into China`s nine dash line map rejects the legal status of Indonesian water under UNCLOS 1982.

Concomitant alpha7 and beta2 nicotinic AChR subunit deficiency leads to impaired energy homeostasis and increased physical activity in mice.

Science.gov (United States)

Somm, Emmanuel; Guérardel, Audrey; Maouche, Kamel; Toulotte, Audrey; Veyrat-Durebex, Christelle; Rohner-Jeanrenaud, Françoise; Maskos, Uwe; Hüppi, Petra S; Schwitzgebel, Valérie M

2014-05-01

Nicotinic acetylcholine receptors (nAChRs) are pentameric ligand-gated cation channels well characterized in neuronal signal transmission. Moreover, recent studies have revealed nAChR expression in nonneuronal cell types throughout the body, including tissues involved in metabolism. In the present study, we screen gene expression of nAChR subunits in pancreatic islets and adipose tissues. Mice pancreatic islets present predominant expression of α7 and β2 nAChR subunits but at a lower level than in central structures. Characterization of glucose and energy homeostasis in α7β2nAChR(-/-) mice revealed no major defect in insulin secretion and sensitivity but decreased glycemia apparently unrelated to gluconeogenesis or glycogenolysis. α7β2nAChR(-/-) mice presented an increase in lean and bone body mass and a decrease in fat storage with normal body weight. These observations were associated with elevated spontaneous physical activity in α7β2nAChR(-/-) mice, mainly due to elevation in fine vertical (rearing) activity while their horizontal (ambulatory) activity remained unchanged. In contrast to α7nAChR(-/-) mice presenting glucose intolerance and insulin resistance associated to excessive inflammation of adipose tissue, the present metabolic phenotyping of α7β2nAChR(-/-) mice revealed a metabolic improvement possibly linked to the increase in spontaneous physical activity related to central β2nAChR deficiency. Copyright © 2014 Elsevier Inc. All rights reserved.

High tsunami risk at northern tip of Sumatra as a result of the activity of the Sumatra Fault Zone (SFZ) combined with coastal landslides

Science.gov (United States)

Haridhi, H. A.; Huang, B. S.; Wen, K. L.; Mirza, A.; Rizal, S.; Purnawan, S.; Fajri, I.; Klingelhoefer, F.; Liu, C. S.; Lee, C. S.; Wilson, C. R.

2017-12-01

The lesson learned from the 12 January 2010, Mw 7.0 Haiti earthquake has shown that an earthquake with strike-slip faulting can produce a significant tsunami. This occasion is rare since in the fact of the fault consist predominantly of lateral motion, which is rarely associated with significant uplift or tsunami generation. Yet, another hint from this event, that this earthquake was accompanied by a coastal landslide. Again, there were only few records of a submarine slides as a primary source that generate a tsunami. Hence, the Haiti Mw 7.0 earthquake was generated by these combined mechanisms, i.e. strike-slip faulting earthquake and coastal landslide. In reflecting this event, the Sumatra region exhibit almost identical situation, where the right lateral strike-slip faulting of Sumatra Fault Zone (SFZ) is located. In this study, we are focusing at the northern tip of SFZ at Aceh Province. The reason we focused our study at its northern tip is that, since the Sumatra-Andaman mega earthquake and tsunami on 26 December 2004, which occurred at the subduction zone, there were no records of significant earthquake along the SFZ, where at this location the SFZ is divided into two faults, i.e. Aceh and Seulimeum faults. This study aimed as a mitigation effort, if an earthquake happened at these faults, do we observe a similar result as that happened at Haiti or not. To do so, we access the high-resolution shallow bathymetry data that acquired through a Community-Based Bathymetric Survey (CBBS), examines five scanned Single Channel Seismic (SCS) reflections data, perform the slope stability analysis and that simulate the tsunami using Cornell Multi-grid Coupled Tsunami Model (COMCOT) model with a combined source of fault activity and submarine landslide. The result shows that, by these combined mechanisms, if the earthquake as large as 7 Mw or larger, it could produce a tsunami as high as 6 meters along the coast. The detailed shallow bathymetric and the slope stability

Implementation of Biplot Analysis for Mapping Elementary and Junior High Schools in West Sumatra Based on National Examination Results 2016

Science.gov (United States)

Amalita, N.; Fitria, D.; Distian, V.

2018-04-01

National examination is an assessment of learning outcomes that aims to assess the achievement of graduate competence nationally. The result of the national examination is used as a mapping of educational issues in order to arrange the national education policy. Therefore the results of National Examination are used, also, as a reference for the admission of new students to continue their education to a higher level. The results of National Examination in West Sumatra in 2016 decreased from the previous year, both elementary schools (SD) and Junior High School level (SMP). This paper aims to determine the characteristics of the National Examination results in each regency / city in West Sumatra for elementary and junior levels by using Bi-plot analysis. The result of Bi-plot Analysis provides the information that the results of the National Examination of Regency / City in West Sumatra Province are quite diverse. At Junior High School level there are 9 of Regencies / Cities which have similar characteristics. English subjects are the greatest diversity among all of subjects. The calculation results of the correlation of each variable in junior high school level are positively correlated. The variables with positive correlation are mathematics that correlates with English. Based on the mark of National Examination for elementary school level in West Sumatra, there are 8 Regencies / Cities have similar characteristics. The correlations of each variable at the elementary level are positively correlated. The variables that have positive correlation are Sciences (IPA) with Language.

Gas Chromatography, GC/Mass Analysis and Bioactivity of Essential Oil from Aerial Parts of Ferulago trifida: Antimicrobial, Antioxidant, AChE Inhibitory, General Toxicity, MTT assay and Larvicidal Activities

Directory of Open Access Journals (Sweden)

Saeed Tavakoli

2017-10-01

Full Text Available Background: We aimed to investigate different biological properties of aerial parts essential oil of Ferulago trifida Boiss and larvicidal activity of its volatile oils from all parts of plant.Methods: Essential oil was prepared by steam distillation and analyzed by Gas chromatography and GC/Mass. Anti­oxidant, antimicrobial, cytotoxic effects and AChE inhibitory of the oil were investigated using DPPH, disk diffusion method, MTT assay and Ellman methods. Larvicidal activity of F. trifida essential oil against malaria vector Anoph­eles stephensi was carried out according to the method described by WHO.Results: In GC and GC/MS analysis, 58 compounds were identified in the aerial parts essential oil, of which E-ver­benol (9.66%, isobutyl acetate (25.73% and E-β-caryophyllene (8.68% were main compounds. The oil showed (IC50= 111.2µg/ml in DPPH and IC50= 21.5 mg/ml in the investigation of AChE inhibitory. Furthermore, the oil demonstrated toxicity with (LD50= 1.1µg/ml in brine shrimp lethality test and with (IC50= 22.0, 25.0 and 42.55 µg/ml on three cancerous cell lines (MCF-7, A-549 and HT-29 respectively. LC50 of stem, root, aerial parts, fruits, and flowers essential oils against larvae of An. stephensi were equal with 10.46, 22.27, 20.50, 31.93 and 79.87ppm respectively. In antimicrobial activities, essential oil was effective on all specimens except Escherichia coli, Asper­gillus niger and Candida albicans.Conclusion: The essential oil showed moderate antioxidant activity, strong antimicrobial properties and good toxic effect in brine shrimp test and MTT assay on three cancerous cell lines.

High Resolution Satellite Remote Sensing of the 2013-2014 Eruption of Sinabung Volcano, Sumatra, Indonesia

Science.gov (United States)

Wessels, R. L.; Griswold, J. P.

2014-12-01

Satellite remote sensing provided timely observations of the volcanic unrest and several months-long eruption at Sinabung Volcano, Indonesia. Visible to thermal optical and synthetic aperture radar (SAR) systems provided frequent observations of Sinabung. High resolution image data with spatial resolutions from 0.5 to 1.5m offered detailed measurements of early summit deformation and subsequent lava dome and lava flow extrusion. The high resolution data were captured by commercial satellites such as WorldView-1 and -2 visible to near-infrared (VNIR) sensors and by CosmoSkyMed, Radarsat-2, and TerraSar-X SAR systems. Less frequent 90 to 100m spatial resolution night time thermal infrared (TIR) observations were provided by ASTER and Landsat-8. The combination of data from multiple sensors allowed us to construct a more complete timeline of volcanic activity than was available via only ground-based observations. This satellite observation timeline documents estimates of lava volume and effusion rates and major explosive and lava collapse events. Frequent, repeat volume estimates suggest at least three high effusion rate pulses of up to 20 m3/s occurred during the first three months of lava effusion with an average effusion rate of 6m3/s from January 2014 to August 2014. Many of these rates and events show some correlation to variations in the Real-time Seismic-Amplitude Measurement (RSAM) documented by the Indonesian Center for Volcanology and Geologic Hazard Mitigation (CVGHM).

Targeting α4β2 nAChRs in CNS disorders: Perspectives on positive allosteric modulation as a therapeutic approach

DEFF Research Database (Denmark)

Grupe, Morten; Grunnet, Morten; Bastlund, Jesper F.

2015-01-01

The nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels broadly involved in regulating neurotransmission in the central nervous system (CNS) by conducting cation currents through the membrane of neurons. Many different nAChR subtypes exist with each their functional character......The nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels broadly involved in regulating neurotransmission in the central nervous system (CNS) by conducting cation currents through the membrane of neurons. Many different nAChR subtypes exist with each their functional...... characteristics, expression pattern and pharmacological profile. The focus of the present MiniReview is on the heteromeric α4β2 nAChR, as activity at this subtype contributes to cognitive functioning through interactions with multiple neurotransmitter systems and is implicated in various CNS disorders...... and temporal aspects of neurotransmission as well as higher subtype selectivity, hypothetically resulting in high clinical efficacy with minimal adverse effects. In this MiniReview, we describe the currently identified compounds, which potentiate the effects of agonists at the α4β2 nAChR. The potential...

Calcium imaging with genetically encoded sensor Case12: Facile analysis of α7/α9 nAChR mutants.

Directory of Open Access Journals (Sweden)

Irina Shelukhina

Full Text Available Elucidation of the structural basis of pharmacological differences for highly homologous α7 and α9 nicotinic acetylcholine receptors (nAChRs may shed light on their involvement in different physiological functions and diseases. Combination of site-directed mutagenesis and electrophysiology is a powerful tool to pinpoint the key amino-acid residues in the receptor ligand-binding site, but for α7 and α9 nAChRs it is complicated by their poor expression and fast desensitization. Here, we probed the ligand-binding properties of α7/α9 nAChR mutants by a proposed simple and fast calcium imaging method. The method is based on transient co-expression of α7/α9 nAChR mutants in neuroblastoma cells together with Ric-3 or NACHO chaperones and Case12 fluorescent calcium ion sensor followed by analysis of their pharmacology using a fluorescence microscope or a fluorometric imaging plate reader (FLIPR with a GFP filter set. The results obtained were confirmed by electrophysiology and by calcium imaging with the conventional calcium indicator Fluo-4. The affinities for acetylcholine and epibatidine were determined for human and rat α7 nAChRs, and for their mutants with homologous residues of α9 nAChR incorporated at positions 117-119, 184, 185, 187, and 189, which are anticipated to be involved in ligand binding. The strongest decrease in the affinity was observed for mutations at positions 187 and 119. The L119D mutation of α7 nAChR, showing a larger effect for epibatidine than for acetylcholine, may implicate this position in pharmacological differences between α7 and α9 nAChRs.

Synthesis and DPPH scavenging assay of reserpine analogues, computational studies and in silico docking studies in AChE and BChE responsible for Alzheimer's disease

Directory of Open Access Journals (Sweden)

Muhammad Yar

2015-03-01

Full Text Available Alzheimer's disease (AD is a fast growing neurodegenerative disorder of the central nervous system and anti-oxidants can be used to help suppress the oxidative stress caused by the free radicals that are responsible for AD. A series of selected synthetic indole derivatives were biologically evaluated to identify potent new antioxidants. Most of the evaluated compounds showed significant to modest antioxidant properties (IC50 value 399.07 140.0±50 µM. Density Functional Theory (DFT studies were carried out on the compounds and their corresponding free radicals. Differences in the energy of the parent compounds and their corresponding free radicals provided a good justification for the trend found in their IC50 values. In silico, docking of compounds into the proteins acetylcholinesterase (AChE and butyrylcholinesterase (BChE, which are well known for contributing in AD disease, was also performed to predict anti-AD potential.

A program to develop the domestic natural gas industry in Indonesia: Case history of two World Bank projects

International Nuclear Information System (INIS)

Klass, D.L.; Khwaja, S.

1992-01-01

Indonesia depends heavily on revenues from the export of LNG and oil, the availability of which appears to be decreasing. It is therefore making a strong effort to accelerate development of a domestic natural gas industry. A high priority has been given to the conversion of power plants and city gas systems, including local industries and commercial facilities, from liquid fuels to natural gas. This will release more oil for export, help to meet the objectives of Repelita V, and provide substantial environmental benefits. The World Bank recently provided loans to the Indonesian Government for two projects that are aimed at substituting natural gas for oil and manufactured gas in domestic markets. One project involves expansion of the gas distribution systems of Indonesia's natural gas utility (PGN) in three cities: Jakarta and Bogor in Java, and Medan in Sumatra. Approximately 350 new industrial, 800 new commercial, and 12,700 new residential natural gas customers are expected from this project. Incremental gas sales are projected to be about 48.1 million CF/d when the project is completed in 1992. The project also includes training programs for PGN staff and an energy pricing policy study to be carried out by Indonesia's Ministry of Mines and Energy. The second project involves expansion of the supply of natural gas for Surabaya and twelve other towns in its vicinity in East Java, and further expansion of Medan's supply system. The gas for Surabaya will be used for about 400 industrial and 150 commercial customers, and 3,600 households. The additional gas supply for Medan will be used for two power plants operated by the state electric utility, PLN. Incremental natural gas sales from this project are projected to be 68 million CF/d when it is

The α7-nACh nicotinic receptor and its role in memory and selected diseases of the central nervous system

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Urszula Baranowska

2017-07-01

Full Text Available α7-nACh is one of the major nicotinic cholinergic receptor subtypes found in the brain. It is broadly expressed in the hippocampal and cortical neurons, the regions which play a key role in memory formation. Although α7-nACh receptors may serve as postsynaptic receptors mediating classical neurotransmission, they usually function as presynaptic modulators responsible for the release of other neurotransmitters, such as glutamate, γ-aminobutyric acid, dopamine, and norepinephrine. They can, therefore, affect a wide array of neurobiological functions. In recent years, research has found that a large number of agonists and positive allosteric modulators of α7-nAChR induce beneficial effects on learning and memory. Consistently, mice deficient in chrna7 (the gene encoding α7-nAChR protein, are characterized by memory deficits. In addition, decreased expression and function of α7-nAChR is associated agoniwith many neurological diseases including schizophrenia, bipolar disorder, learning disability, attention deficit hyperactivity disorder, Alzheimer disease, autism, and epilepsy. In the recent years many animal experiments and clinical trials using α7-nAChR ligands were conducted. The results of these studies strongly indicate that agonists and positive allosteric modulators of α7-nAChR are promising therapeutic agents for diseases associated with cognitive deficits.

Phenomenon of Women Marginalization in Poor Family in Pakpak Community (A Case Study in Pegagan Julu Village, Sumbul Subdistrict, Dairi Regency - North Sumatra - Indonesia

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Hadriana Marhaeni Munthe

2017-06-01

Full Text Available This article is taken from the study of marginalization cases experienced by Pakpak women of rural poor families. The study was conducted in Pegagan village of Sumbul Subdistrict, Dairi, North Sumatra province. The marginalization phenomenon is shown in some aspects; restrictions on women's access to formal education, tendency of dropping out of school, having no inheritance rights and no role in the decision making of custom. Related to this phenomenon, the research question of this study is how the process of marginalization experienced by women in their family is.Marxist structural feminist perspective and qualitative approach with feminist perspective were used to answer the research question. The findings of the study finally show that the structured patriarchy ideology as gender ideology in family becomes the cause of women marginalization. Patriarchy becoming gender ideological construction in Pakpak family is interpreted and expressed in the form of private patriarchy, that is a hegemonizing system or structure of men power that has dominated and subordinated social position of women in Pakpak families.

Going up in Smoke? A Review of nAChRs-based Treatment Strategies for Improving Cognition in Schizophrenia

Science.gov (United States)

Boggs, Douglas L.; Carlson, Jon; Cortes-Briones, Jose; Krystal, John H.; D’Souza, D. Cyril

2015-01-01

Cognitive impairment is known to be a core deficit in schizophrenia. Existing treatments for schizophrenia have limited efficacy against cognitive impairment. The ubiquitous use of nicotine in this population is thought to reflect an attempt by patients to self-medicate certain symptoms associated with the illness. Concurrently there is evidence that nicotinic receptors that have lower affinity for nicotine are more important in cognition. Therefore, a number of medications that target nicotinic acetylcholine receptors (nAChRs) have been tested or are in development. In this article we summarize the clinical evidence of nAChRs dysfunction in schizophrenia and review clinical studies testing either nicotine or nicotinic medications for the treatment of cognitive impairment in schizophrenia. Some evidence suggests beneficial effects of nAChRs based treatments for the attentional deficits associated with schizophrenia. Standardized cognitive test batteries have failed to capture consistent improvements from drugs acting at nAChRs. However, more proximal measures of brain function, such as ERPs relevant to information processing impairments in schizophrenia, have shown some benefit. Further work is necessary to conclude that nAChRs based treatments are of clinical utility in the treatment of cognitive deficits of schizophrenia. PMID:24345265

ENSO modulation of seasonal rainfall and extremes in Indonesia

Science.gov (United States)

Supari; Tangang, Fredolin; Salimun, Ester; Aldrian, Edvin; Sopaheluwakan, Ardhasena; Juneng, Liew

2017-12-01

This paper provides a detailed description of how ENSO events affect seasonal and extreme precipitation over Indonesia. Daily precipitation data from 97 stations across Indonesia covering the period from 1981 to 2012 were used to investigate the effects of El Niño and La Niña on extreme precipitation characteristics including intensity, frequency and duration, as defined based on a subset of the Expert Team on Climate Change Detection and Indices (ETCCDI). Although anomalous signals in these three indices were consistent with those of total rainfall, anomalies in the duration of extremes [i.e., consecutive dry days (CDD) and consecutive wet days (CWD)] were much more robust. El Niño impacts were particularly prominent during June-July-August (JJA) and September-October-November (SON), when anomalously dry conditions were experienced throughout the country. However, from SON, a wet anomaly appeared over northern Sumatra, later expanding eastward during December-January-February (DJF) and March-April-May (MAM), creating contrasting conditions of wet in the west and dry in the east. We attribute this apparent eastward expansion of a wet anomaly during El Niño progression to the equatorial convergence of two anti-cyclonic circulations, one residing north of the equator and the other south of the equator. These anti-cyclonic circulations strengthen and weaken according to seasonal changes and their coupling with regional seas, hence shaping moisture transport and convergence. During La Niña events, the eastward expansion of an opposite (i.e., dry) anomaly was also present but less prominent than that of El Niño. We attribute this to differences in regional ocean—atmosphere coupling, which result in the contrasting seasonal evolution of the two corresponding anomalous cyclonic circulations and in turn suggests the strong nonlinearity of El Niño and La Niña responses over the Maritime Continent. Based on the seasonal behaviour of anomalous CDD and CWD, we

In search of allosteric modulators of a7-nAChR by solvent density guided virtual screening.

Science.gov (United States)

Dey, Raja; Chen, Lin

2011-04-01

Nicotinic acetylcholine receptors (nAChR) are pentameric ligand gated ion channels whose activity can be modulated by endogenous neurotransmitters as well as by synthetic ligands that bind the same or distinct sites from the natural ligand. The subtype of α7 nAChR has been considered as a potenial therapeutic target for Alzheimer's disease, schizophrenia and other neurological and psychiatric disorders. Here we have developed a homology model of α7 nAChR based on two high resolution crystal structures with Brookhaven Protein Data Bank (PDB) codes 2QC1 and 2WN9 for threading on one monomer and then for building a pentamer, respectively. A number of small molecule binding sites are identified using Pocket Finder (J. An, M. Tortov, and R. Abagyan, Molecular & Cellular Proteomics, 4.6, 752-761 (2005)) of Internal Coordinate Mechanics (ICM). Remarkably, these computer-identified sites match perfectly with ordered solvent densities found in the high-resolution crystal structure of α1 nAChR, suggesting that the surface cavities in the α7 nAChR model are likely binding sites of small molecules. A high throughput virtual screening by flexible ligand docking of 5008 small molecule compounds was performed at three potential allosteric modulator (AM) binding sites of α7 nAChR using Molsoft ICM software (R. Abagyan, M. Tortov and D. Kuznetsov, J Comput Chem 15, 488-506, (1994)). Some experimentally verified allosteric modulators of α7 like CCMI comp-6, LY 7082101, 5-HI, TQS, PNU-120596, genistein, and NS-1738 ranked among top 100 compounds, while the rest of the compounds in the list could guide further search for new allosteric modulators.

A Preliminary Case Study for Rectenna Sites in Indonesia

Science.gov (United States)

Purwanto, Y.; Collins, P.

2004-12-01

include the possibilities of environmental damage due to the high intensity electromagnetic energy from outer space. As is well known, most Indonesian land areas consist of tropical forest which is rich with flora and fauna; these may face risks from receiving such electromagnetic energy illumination. It is considered that rectenna location selection in the main islands (like Java, Sumatra, Kalimantan, Sulawesi, Irian, etc.) which are densely populated should be avoided. The same conditions should also be considered for the location in the forest, due to the flora and fauna damage possibilities during the physical development process. From this study it can be considered that the appropriate rectenna location should be placed on uninhabited small coral islands (atoll) sized about 5x5 km 2 , which are located along the equator. Such coral islands are vailable in the western and eastern parts of Indonesia. It is also considered that such coral islands should be located not too far from major inhabited islands, that is about 5-10 km offshore due to the convenience of physical rectenna development and electric energy distribution to the mainland. Such a coral island is to be considered to suffer minimal effects if the surface is illuminated by microwave energy. The same effect suffered by resident creatures like birds and reptiles should also be minimal. Because of the very limited infrastructure available on the mainland (and likely no facilities at all), a rectenna development study should consider all technical risks. For example, antenna installation and building of other support components should be done in such a location so that sea surface transportation can be easily performed. Communication system may be performed only by radio transceivers and satellite systems. The existence of human resources, that are needed to physically develop buildings, must be considered since the location is a remote island. There will also be no expert staff available, so that they will

Labor and Population Program: The Dangers of Smoke Haze. Mortality in Malaysia from Indonesian Forest Fires

National Research Council Canada - National Science Library

2002-01-01

Between April and November of 1997, a widespread series of forest fires in Indonesia-particularly in the provinces of Sumatra and Kalimantan-threw a blanket of thick, smoky haze over a large portion of Southeast Asia...

Indian Ocean Earthquake and Tsunami: Humanitarian Assistance and Relief Operations

National Research Council Canada - National Science Library

Margesson, Rhoda

2005-01-01

On December 26, 2004, a magnitude 9.0 undersea earthquake off the west coast of northern Sumatra, Indonesia, unleashed a tsunami that affected more than 12 countries throughout south and southeast Asia and stretched as far...

Nicotine-Induced Effects on Nicotinic Acetylcholine Receptors (nAChRs), Ca2+ and Brain-Derived Neurotrophic Factor (BDNF) in STC-1 Cells.

Science.gov (United States)

Qian, Jie; Mummalaneni, Shobha K; Alkahtani, Reem M; Mahavadi, Sunila; Murthy, Karnam S; Grider, John R; Lyall, Vijay

2016-01-01

In addition to the T2R bitter taste receptors, neuronal nicotinic acetylcholine receptors (nAChRs) have recently been shown to be involved in the bitter taste transduction of nicotine, acetylcholine and ethanol. However, at present it is not clear if nAChRs are expressed in enteroendocrine cells other than beta cells of the pancreas and enterochromaffin cells, and if they play a role in the synthesis and release of neurohumoral peptides. Accordingly, we investigated the expression and functional role of nAChRs in enteroendocrine STC-1 cells. Our studies using RT-PCR, qRT-PCR, immunohistochemical and Western blotting techniques demonstrate that STC-1 cells express several α and β nAChR subunits. Exposing STC-1 cells to nicotine acutely (24h) or chronically (4 days) induced a differential increase in the expression of nAChR subunit mRNA and protein in a dose- and time-dependent fashion. Mecamylamine, a non-selective antagonist of nAChRs, inhibited the nicotine-induced increase in mRNA expression of nAChRs. Exposing STC-1 cells to nicotine increased intracellular Ca2+ in a dose-dependent manner that was inhibited in the presence of mecamylamine or dihydro-β-erythroidine, a α4β2 nAChR antagonist. Brain-derived neurotrophic factor (BDNF) mRNA and protein were detected in STC-1 cells using RT-PCR, specific BDNF antibody, and enzyme-linked immunosorbent assay. Acute nicotine exposure (30 min) decreased the cellular content of BDNF in STC-1 cells. The nicotine-induced decrease in BDNF was inhibited in the presence of mecamylamine. We also detected α3 and β4 mRNA in intestinal mucosal cells and α3 protein expression in intestinal enteroendocrine cells. We conclude that STC-1 cells and intestinal enteroendocrine cells express nAChRs. In STC-1 cells nAChR expression is modulated by exposure to nicotine in a dose- and time-dependent manner. Nicotine interacts with nAChRs and inhibits BDNF expression in STC-1 cells.

The analysis of labor force participation in rubber smallholding sector in Banyuasin Regency, South Sumatera, Indonesia

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M. Yusuf

2015-06-01

Full Text Available The fact is that natural rubber has a strategic role as it is one of the commodities industry tropical crops. In addition, it also has important and strategic role in sup-porting the national economy, primarily as a source of livelihood of millions of rub-ber farmers in rural areas. This study analyzed the potential of using family labor in rubber smallholding sector in Banyuasin Regency, South Sumatra Province, Indo-nesia. The total sample used for the study was 280 respondents of households. Data was analyzed using multiple regression analyses. The multiple regression analysis used to identify the determinants of labor force participation decision regarding work in the rubber smallholding in the study area such as rubber production (kg per year per hectare, number of family workers, age of family head, location of dwelling, education of family head, and average years of schooling of family workers. Based on the analysis, only two factors affected significantly family labor force participation outside their smallholdings, namely number of family labor and education of family head.

Variations in sea surface roughness induced by the 2004 Sumatra-Andaman tsunami

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O. A. Godin

2009-07-01

Full Text Available Observations of tsunamis away from shore are critically important for improving early warning systems and understanding of tsunami generation and propagation. Tsunamis are difficult to detect and measure in the open ocean because the wave amplitude there is much smaller than it is close to shore. Currently, tsunami observations in deep water rely on measurements of variations in the sea surface height or bottom pressure. Here we demonstrate that there exists a different observable, specifically, ocean surface roughness, which can be used to reveal tsunamis away from shore. The first detailed measurements of the tsunami effect on sea surface height and radar backscattering strength in the open ocean were obtained from satellite altimeters during passage of the 2004 Sumatra-Andaman tsunami. Through statistical analyses of satellite altimeter observations, we show that the Sumatra-Andaman tsunami effected distinct, detectable changes in sea surface roughness. The magnitude and spatial structure of the observed variations in radar backscattering strength are consistent with hydrodynamic models predicting variations in the near-surface wind across the tsunami wave front. Tsunami-induced changes in sea surface roughness can be potentially used for early tsunami detection by orbiting microwave radars and radiometers, which have broad surface coverage across the satellite ground track.

The Influence of ENSO to the Rainfall Variability in North Sumatra Province

Science.gov (United States)

Irwandi, H.; Pusparini, N.; Ariantono, J. Y.; Kurniawan, R.; Tari, C. A.; Sudrajat, A.

2018-04-01

The El Niño Southern Oscillation (ENSO) is a global phenomenon that affects the variability of rainfall in North Sumatra. The influence of ENSO will be different for each region. This review will analyse the influence of ENSO activity on seasonal and annual rainfall variability. In this research, North Sumatra Province will be divided into 4 (four) regions based on topographical conditions, such as: East Coast (EC), East Slope (ES), Mountains (MT), and West Coast (WC). The method used was statistical and descriptive analysis. Data used in this research were rainfall data from 15 stations / climate observation posts which spread in North Sumatera region and also anomaly data of Nino 3.4 region from period 1981-2016. The results showed that the active El Niño had an effect on the decreasing the rainfall during the period of DJF, JJA and SON in East Coast, East Slope, and Mountains with the decreasing of average percentage of annual rainfall up to 7%. On the contrary, the active La Nina had an effect on the addition of rainfall during the period DJF and JJA in the East Coast and Mountains with the increasing of average percentage of annual rainfall up to 6%.

Shallow shear-wave reflection seismics in the tsunami struck Krueng Aceh River Basin, Sumatra

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U. Polom

2008-01-01

Full Text Available As part of the project "Management of Georisk" (MANGEONAD of the Federal Institute for Geosciences and Natural Resources (BGR, Hanover, high resolution shallow shear-wave reflection seismics was applied in the Indonesian province Nanggroe Aceh Darussalam, North Sumatra in cooperation with the Government of Indonesia, local counterparts, and the Leibniz Institute for Applied Geosciences, Hanover. The investigations were expected to support classification of earthquake site effects for the reconstruction of buildings and infrastructure as well as for groundwater exploration. The study focussed on the city of Banda Aceh and the surroundings of Aceh Besar. The shear-wave seismic surveys were done parallel to standard geoengineering investigations like cone penetrometer tests to support subsequent site specific statistical calibration. They were also partly supplemented by shallow p-wave seismics for the identification of (a elastic subsurface parameters and (b zones with abundance of groundwater. Evaluation of seismic site effects based on shallow reflection seismics has in fact been found to be a highly useful method in Aceh province. In particular, use of a vibratory seismic source was essential for successful application of shear-wave seismics in the city of Banda Aceh and in areas with compacted ground like on farm tracks in the surroundings, presenting mostly agricultural land use areas. We thus were able to explore the mechanical stiffness of the subsurface down to 100 m depth, occasionally even deeper, with remarkably high resolution. The results were transferred into geotechnical site classification in terms of the International Building Code (IBC, 2003. The seismic images give also insights into the history of the basin sedimentation processes of the Krueng Aceh River delta, which is relevant for the exploration of new areas for construction of safe foundations of buildings and for identification of fresh water aquifers in the tsunami

Inhibitory effects of psychotropic drugs on the acetylcholine receptor-operated potassium current (IK.ACh) in guinea-pig atrial myocytes.

Science.gov (United States)

Okada, Muneyoshi; Watanabe, Shinya; Matada, Takashi; Asao, Yoko; Hamatani, Ramu; Yamawaki, Hideyuki; Hara, Yukio

2013-01-01

Influences of psychotropic drugs, six antipsychotics and three antidepressants, on acetylcholine receptor-operated potassium current (IK.ACh) were examined by a whole-cell patch clamp method in freshly isolated guinea-pig atrial myocyte. IK.ACh was induced by a superfusion of carbachol (CCh) or by an intracellular application of guanosine 5'-[thio] triphosphate (GTPγS). To elucidate mechanism for anticholinergic action, IC50 ratio, the ratio of IC50 for GTPγS-activated IK.ACh to CCh-induced IK.ACh, was calculated. Antipsychotics and antidepressants inhibited CCh-induced IK.ACh in a concentration-dependent manner. The IC50 values were as follows; chlorpromazine 0.53 μM, clozapine 0.06 μM, fluphenazine 2.69 μM, haloperidol 2.66 μM, sulpiride 42.3 μM, thioridazine 0.07 μM, amitriptyline 0.03 μM, imipramine 0.22 μM and maprotiline 1.81 μM. The drugs, except for sulpiride, inhibited GTPγS-activated IK.ACh with following IC50 values; chlorpromazine 1.71 μM, clozapine 14.9 μM, fluphenazine 3.55 μM, haloperidol 2.73 μM, thioridazine 1.90 μM, amitriptyline 7.55 μM, imipramine 7.09 μM and maprotiline 5.93 μM. The IC50 ratio for fluphenazine and haloperidol was close to unity. The IC50 ratio for chlorpromazine, clozapine, thioridazine, amitriptyline, imipramine and maprotiline was much higher than unity. The present findings suggest that the psychotropics studied suppress IK.ACh. Chlorpromazine, clozapine, thioridazine, amitriptyline, imipramine, maprotiline and sulpiride are preferentially acting on muscarinic receptor. Fluphenazine and haloperidol may act on G protein and/or potassium channel.

PERILAKU BERISIKO KESEHATAN DAN FAKTOR YANG MEMPENGARUHINYA PADA REMAJA SEKOLAH MENENGAH PERTAMA DI JAWA DAN SUMATRA

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Rachmalina Soerachman

2016-09-01

Full Text Available ABSTRACTSeveral behaviour health risks such as lack of physical activity, smoking and violence have contributed tothe health status among adolescents. Those behaviour health risks can be associated with familyrelationship, school environment and other related social cultural and economy determinants.Consequently, those behaviour risk factors may lead to certain non-communicable disease. To describe thebehaviour risk factors among adolescents and their determinant factors. This study employed a two-stagecluster sample design to produce a representative sample of students in 7th-9th grade, aged 13 — 15 years.In this study 3,116 questionnaires were completed in 49 schools in Java and Sumatra islands. Data wasanalyzed descriptively to provide proportion of certain behavior risk factors. Data analysis was done usingEpi-info. Study showed 10.9%-21.6% of boys students in Java and Sumatra smoked a day or over in theperiod of one month. Among the smoking students about 71.1% of adolescents started smoking at aged 13years or younger. Approximately 37%- 41% adolescents experienced having physical fighting at least onceor more during the last one year. The prevalence of physical fighting was higher among boys than girls.The behavior health risks are alarming and need further specific intervention based on issues priority toimprove the health behavior among adolescents in order to prevent certain non-communicable disease inthe older age.Keywords: Health behaviour, Factors, Students ABSTRAKKurangnya aktifitas fisik, merokok dan kekerasan adalah beberapa perilaku yang diidentifikasi sangatberpengaruh pada kesehatan pelajar khususnya anak remaja. Perilaku-perilaku berisiko tersebut disebabkanoleh beberapa faktor diantaranya adalah lingkungan keluarga, sekolah dan lainnya yang akibatnya dapatmenjurus ke masalah penyakit tidak menular. Studi ini bertujuan untuk mendeskripsikan perilaku-perilakuberisiko pada pelajar dan faktor-faktor yang mempengaruhinya

Deposition of a-C:H films on a nanotrench pattern by bipolar PBII and D

International Nuclear Information System (INIS)

Hirata, Yuki; Nakahara, Yuya; Nagato, Keisuke; Choi, Junho

2016-01-01

In this study, hydrogenated amorphous carbon (a-C:H) films were deposited on a nanotrench pattern (300 nm pitch, aspect ratio: 2.0) by bipolar-type plasma based ion implantation and deposition technique (bipolar PBII and D), and the effects of bipolar pulse on the film properties were investigated. Moreover, the behaviour of ions and radicals surrounding the nanotrench was analyzed to clarify the coating mechanism and properties of the a-C:H films on the nanotrench. Further, thermal nanoimprint lithography was carried out using the nanotrench pattern coated with a-C:H films as the mold, and the mold release properties were evaluated. All nanotrench surfaces were successfully coated with the a-C:H films, but the film thickness on the top, sidewall, and bottom surfaces of the trench were not uniform. The surface roughness of the a-C:H films was found to decrease at a higher positive voltage; this happens due to the higher electron temperature around the nanotrench because of the surface migration of plasma particles arrived on the trench. The effects of the negative voltage on the behaviour of ions and radicals near the sidewall of the nanotrench are quite similar to those near the microtrench reported previously (Park et al 2014 J. Phys. D: Appl. Phys . 47 335306). However, the positive pulse voltage was also found to affect the behaviour of ions and radicals near the sidewall surface. The incident angles of ions on the sidewall surface increased with the positive pulse voltage because the energy of incoming ions on the trench decreases with increasing positive voltage. Moreover, the incident ion flux on the sidewall is affected by the positive voltage history. Further, the radical flux decreases with increasing positive voltage. It can be concluded that a higher positive voltage at a lower negative voltage condition is good to obtain better film properties and higher film thickness on the sidewall surface. Pattern transfer properties for the nanoimprint formed by

Prevalence of Cryptosporidium spp., Enterocytozoon bieneusi, Encephalitozoon spp. and Giardia intestinalis in Wild, Semi-Wild and Captive Orangutans (Pongo abelii and Pongo pygmaeus) on Sumatra and Borneo, Indonesia.

Science.gov (United States)

Mynářová, Anna; Foitová, Ivona; Kváč, Martin; Květoňová, Dana; Rost, Michael; Morrogh-Bernard, Helen; Nurcahyo, Wisnu; Nguyen, Cathleen; Supriyadi, Supriyadi; Sak, Bohumil

2016-01-01

Orangutans are critically endangered primarily due to loss and fragmentation of their natural habitat. This could bring them into closer contact with humans and increase the risk of zoonotic pathogen transmission. To describe the prevalence and diversity of Cryptosporidium spp., microsporidia and Giardia intestinalis in orangutans at seven sites on Sumatra and Kalimantan, and to evaluate the impact of orangutans' habituation and location on the occurrence of these zoonotic protists. The overall prevalence of parasites in 298 examined animals was 11.1%. The most prevalent microsporidia was Encephalitozoon cuniculi genotype II, found in 21 animals (7.0%). Enterocytozoon bieneusi genotype D (n = 5) and novel genotype Pongo 2 were detected only in six individuals (2.0%). To the best of our knowledge, this is the first report of these parasites in orangutans. Eight animals were positive for Cryptosporidium spp. (2.7%), including C. parvum (n = 2) and C. muris (n = 6). Giardia intestinalis assemblage B, subtype MB6, was identified in a single individual. While no significant differences between the different human contact level groups (p = 0.479-0.670) or between the different islands (p = 0.992) were reported in case of E. bieneusi or E. cuniculi, Cryptosporidium spp. was significantly less frequently detected in wild individuals (p < 2×10-16) and was significantly more prevalent in orangutans on Kalimantan than on Sumatra (p < 2×10-16). Our results revealed that wild orangutans are significantly less frequently infected by Cryptosporidium spp. than captive and semi-wild animals. In addition, this parasite was more frequently detected at localities on Kalimantan. In contrast, we did not detect any significant difference in the prevalence of microsporidia between the studied groups of animals. The sources and transmission modes of infections were not determined, as this would require repeated sampling of individuals, examination of water sources, and sampling of humans

Prevalence of Cryptosporidium spp., Enterocytozoon bieneusi, Encephalitozoon spp. and Giardia intestinalis in Wild, Semi-Wild and Captive Orangutans (Pongo abelii and Pongo pygmaeus on Sumatra and Borneo, Indonesia.

Directory of Open Access Journals (Sweden)

Anna Mynářová

Full Text Available Orangutans are critically endangered primarily due to loss and fragmentation of their natural habitat. This could bring them into closer contact with humans and increase the risk of zoonotic pathogen transmission.To describe the prevalence and diversity of Cryptosporidium spp., microsporidia and Giardia intestinalis in orangutans at seven sites on Sumatra and Kalimantan, and to evaluate the impact of orangutans' habituation and location on the occurrence of these zoonotic protists.The overall prevalence of parasites in 298 examined animals was 11.1%. The most prevalent microsporidia was Encephalitozoon cuniculi genotype II, found in 21 animals (7.0%. Enterocytozoon bieneusi genotype D (n = 5 and novel genotype Pongo 2 were detected only in six individuals (2.0%. To the best of our knowledge, this is the first report of these parasites in orangutans. Eight animals were positive for Cryptosporidium spp. (2.7%, including C. parvum (n = 2 and C. muris (n = 6. Giardia intestinalis assemblage B, subtype MB6, was identified in a single individual. While no significant differences between the different human contact level groups (p = 0.479-0.670 or between the different islands (p = 0.992 were reported in case of E. bieneusi or E. cuniculi, Cryptosporidium spp. was significantly less frequently detected in wild individuals (p < 2×10-16 and was significantly more prevalent in orangutans on Kalimantan than on Sumatra (p < 2×10-16.Our results revealed that wild orangutans are significantly less frequently infected by Cryptosporidium spp. than captive and semi-wild animals. In addition, this parasite was more frequently detected at localities on Kalimantan. In contrast, we did not detect any significant difference in the prevalence of microsporidia between the studied groups of animals. The sources and transmission modes of infections were not determined, as this would require repeated sampling of individuals, examination of water sources, and sampling of

Geochemical evidence for different peat sources in the Siak estuary and along the east coast of Sumatra, Indonesia

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R. Wöstmann

2012-02-01

Full Text Available The distribution pattern of selected biomarkers extracted from samples of outcropping peat from the Siak river, its estuary, the coast around Dumai and the island of Bengkalis have been investigated by gas chromatography (GC and combined gas chromatography/mass spectrometry (GC/MS, and compared with samples of eroded peat washed ashore (re-deposited on the coastline of Sumatra. Geochemical analyses of n-alkanes, n-alkanols, n-alkanoic acids, steroids and triterpenoids show that outcropping and re-deposited peats have different chemical compositions. The outcropping peats around Dumai, Bengkalis and in the Siak River estuary contain high concentrations of the pentacyclic triterpenoid taraxerol, a typical constituent of the mangrove species Rhizophora. A comparison with the lipid composition of leaves from the fringing mangrove species (Avicennia alba, Sonneratia alba and Rhizophora apiculata showed that only R. apiculata contains significant amounts of taraxerol. Taraxerol was completely absent from the leaves of A. alba and S. alba. This suggests that the peats outcropping around Dumai, Bengkalis and in the Siak estuary must be formed by a dominant input of mangroves of the Rhizophora family. The n-alkane distribution patterns of the outcropping peats near Dumai and the Siak estuary are similar to those of the surrounding mangrove vegetation with a maximum at C31 and a strong predominance of odd over even carbon numbers in all samples. Biomarker analysis of eroded peats washed ashore along the coastline around Dumai and the Siak estuary shows a different lipid composition with high amounts of the triterpenoids friedelin, α-amyrin and β-amyrin. These compounds are typical biomarkers for tropical forest vegetation as found along the Siak River and for peats eroding at upstream river banks. The n-alkanol distribution patterns of re-deposited peats also indicate a different origin for their organic matter. Peats re-deposited in the Siak estuary

Using Isotopes to Reconstruct Mammalian Diet, Migration and Paleoenvironment for Hominin Sites in Indonesia

Science.gov (United States)

Wershow, H.; Janssen, R.; Vonhof, H.; Lubbe, J. V. D.; Joordens, J. J.; Koutamanis, D. S.; Puspaningrum, M. R.; de Vos, J.; Reijmer, J.

2015-12-01

Climate plays a prominent role in ecosystem development in the biodiversity hotspot Sundaland (Malaysia and western Indonesia) throughout the Quaternary. Recurrent isolation and connection of the islands to mainland Asia due to sea level fluctuations has enabled repeated biotic migrations and encouraged genetic speciation. These migration waves also brought Homo erectus to Java. Together with extensive and well-documented collections of other terrestrial species, these hominin fossils form faunal assemblages of which the paleoenvironmental and paleogeographical background is poorly known. Using carbon, oxygen and strontium isotopes, we have reconstructed the paleoenvironmental and paleoecological conditions of several Holocene and Pleistocene fossil sites on Sumatra and Java, Indonesia. Carbon (∂13C) and oxygen (∂18O) isotope analysis of well-preserved herbivore teeth enamel reveals a marked contrast between C3-dominated diets in warmer periods, and C4-dominated diets in cooler periods, reflecting the distinct changes in Sundaland vegetation cover between glacials and interglacials. These isotope patterns allow us to assign the appropriate climatic background to some of the older fossil assemblages from Java, for which dating uncertainty does not allow direct assignment to glacial or interglacial conditions. The stable isotope signatures of herbivores from Trinil and Sangiran, sites well-known for the fossil occurrence of Homo erectus, indicate glacial conditions. The isotope data of several H. erectus fossils from these sites seem to be in line with such an interpretation. Furthermore, we applied strontium (87Sr/86Sr) isotope analyses to a sample subset. The preliminary data show distinct Sr-isotope ratios for different sites, providing clues for the applicability of this isotope technique in detecting climate-related mobility of Sundaland fossil faunas.

Megaprosthesis limb salvage surgery: Outcome and challenges in treating advanced bone tumour cases in vast archipelago in Indonesia. A case series

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Achmad Fauzi Kamal

Full Text Available Introduction: Limb salvage is considered as a more popular option in Indonesia, as amputation is considered offensive and taboo for many Indonesian cultures and societies. We evaluated the outcome of a series of LSSs with megaprosthesis and their challenges during treatments in Indonesia as the biggest archipelago nation in the world. Methods: Thirty-two patients originated from different islands in Indonesia with advanced lower extremity bone tumours were prospectively reviewed. Data was obtained from surgeries, which was conducted between 2011 and 2015 by two orthopaedic oncologist at Cipto Mangunkusumo Hospital. Functional outcome using musculoskeletal tumour society (MSTS score and oncological outcome were evaluated manually during every outpatient visit at 3, 6, 12 and 24 months. Results: Eight patients originate from Sumatra, one from Moluccas island, and twenty-three based in the Java island. We documented fourteen osteosarcomas, two cases of metastatic bone disease, fifteen giant cell tumours, and one chondromyxoid fibroma. Compared to preoperative score (mean 5.3, MSTS Score range 0–10, postoperative result (mean 25.2, MSTS Score range 53.3–90 at two year revealed 4.75 fold of improvement. Nearly half of the patient (40.6% showed excellent score (MSTS Score range 76.6–96.6 after one year. We reported several complications including: infection, knee dislocation, mechanism extensor disturbance, amputation, and nerve injury. Lower MSTS score was correlated with higher serum alkaline phosphatase (SAP (p = 0,031 and increase intraoperative blood loss (p = 0,033. Complication was found to be associated with tumours that underwent extensive soft tissue reconstruction procedure (p = 0,021. Conclusion: Functional outcome up to 24 months recorded satisfying result. Several complications occurred during our study also passed struggles for our patients during follow up care due to geographical challenges. Nevertheless, for carefully

Pola Spasial, Temporal dan Perilaku Deforestasi di Sumatera

OpenAIRE

rijal, syamsu; saleh, m. buce; jaya, i Nengah Surati; tiryana, tatang

2016-01-01

Penelitian ini membahas tentang formula baru penilaian deforestasi di Sumatera-Indonesia dan dunia serta membahas tentang model spasial deforestasi berdasarkan driving force dan pola spasial deforestasi ABSTRAK SYAMSU RIJAL. Pattern of spatial, temporal and behavioral deforestation in Sumatra. Supervised by M BUCE SALEH, I NENGAH SURATI JAYA, dan TATANG TIRYANA. Deforestation in Indonesia and even in the world has been commonly been assessed based on the rate and area size o...

Genetic variations of Lansium domesticum Corr. accessions from Java, Sumatra and Ceram based on Random Amplified Polymorphic DNA fingerprints

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KUSUMADEWI SRI YULITA

2011-07-01

Full Text Available Yulita KS (2011 Genetic variations of Lansium domesticum Corr. accessions from Java, Bengkulu and Ceram based on Random Amplified Polymorphic DNA fingerprints. Biodiversitas 12: 125-130. Duku (Lansium domesticum Corr. is one of popular tropical fruits in SE Asia. The spesies has three varieties, known as duku, langsat and kokosan; and duku is the most popular one for being the sweetiest fruit. Indonesia has several local varieties of duku, such as duku Condet, duku Sumber and duku Palembang. This present study aimed to assess genetic diversity of 47 accessions of duku from Java, Sumatra, and Ceram based on RAPD fingerprints. Ten RAPD’s primers were initially screened and five were selected for the analysis. These five primers (OPA 7, 13, 18, OPB 7, and OPN 12 generated 53 scorable bands with an average of 10.6 polymorphic fragment per primer. Percentage of polymorphism ranged from 16.89% (OPA 7 and OPN 12 to 24.54% (OPB 7 with an average of 20.16% polymorphism. OPB 7 at 450 bp was exclusively possessed by accession 20 (Java, OPA 18 at 500 bp was by accession 6 (Java, 550 bp by 3 clones from Bengkulu. While OPN 12 at 300 bp and OPA 13 at 450 bp were shared among the accessions. Clustering analysis was performed based on RAPD profiles using the UPGMA method. The range of genetic similarity value among accessions was 0.02-0.65 suggesting high variation of gene pool existed among accessions.

Escherichia coli contamination of babies' food-serving utensils in a district of West Sumatra, Indonesia.

Science.gov (United States)

Kusuma, Aria; Eryando, Tris; Susanna, Dewi

2012-01-01

Contamination of baby's complementary food may occur with Escherichia coli from several sources including unclean utensils. We examined the relationship between socio-economic conditions, environmental factors, characteristics of food handlers and contamination of babies food-serving utensils with E. coli. The study was conducted in 21 villages of the Community Health Centre (CHC) Selayo in Indonesia. A cross-sectional design was used. A sample of 142 households, which had a 6-12 month-old baby on complementary food, was chosen randomly using midwives' registration books. Respondents were interviewed using a semi-structured questionnaire. Check-lists were used for observations. Standard laboratory methods were used for collection of specimen and confirmation of contamination with E. coli. More than half of the respondents (59.2%) used water that had high risk of contamination and 61.3% of the latrines did not meet the criteria of a healthy latrine. Waste management practices of nearly all respondents (97.9%) were below the standards set by the Ministry of Health. More than half of the respondents (68.3%) did not wash their hands with soap for 20 seconds and 52.1% did not use flowing water for washing hands. Majority of the respondents' hands (57%, 81/142) and 72.2% (104/142) of the eating utensils were found to be contaminated by E. coli. Contaminated hands of food handlers were more likely to contaminate the babies food-serving utensils (OR: 3.7; 95%CI: 1.62-8.46, p 0.002). Contamination of the hands of food handler was associated with contamination of babies food-serving utensils by E. coli. Hence, food handlers should be trained on proper hand washing methods.

Halving Poverty in Indonesia

OpenAIRE

Auwalin, Ilmiawan

2009-01-01

This study extends the literature on relationship between economic growth, income inequalities, and poverty reduction. We discuss poverty reduction, using the case ofIndonesia, as one of the Millennium Development Goals declared by the United Nations General Assembly in September 2000. Using provincial level data of Indonesia from 1993 to 2000, we examine the required conditions in order to halve the poverty in Indonesia by2015. The result of analysis shows that Indonesia would need to achiev...

Fabrication of a Highly-sensitive Acetylcholine Sensor Based on AChOx Immobilized Smart-chips

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M. M. RAHMAN

2011-03-01

Full Text Available Acetylcholine (ACh sensor based on acetylcholine oxidase (AChOx on EDC activated thioglycolic acid self-assembled monolayer (TGA-SAM using smart-chip has been developed. The simple cyclic voltammetry (CV, at 0.1 V/s technique is performed in total investigation, where 0.5M K3Fe(CN6 is utilized as a standard mediator in phosphate buffer solution (PBS, 0.1M. The ACh sensor exhibited a lower detection limit (DL, 0.1392 ± 0.005 nM, a wide linear dynamic range (LDR, 1.0 nM to 1.0 mM, good linearity (R=0.9951, and higher sensitivity (7.3543 ± 0.2 μAμM-1cm-2, and required small sample volume (70.0 μL as well as good stability and reproducibility. The smart-chip system employed a simple and efficient approach to the immobilization of enzymes onto active sensitive surface, which can enhance sensor performances to a large group of bio-molecules for wide range of biomedical applications in health care fields.

Functionality and stability data of detergent purified nAChR from Torpedo using lipidic matrixes and macroscopic electrophysiology

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Luis F. Padilla-Morales

2016-03-01

Full Text Available The presented data provides additional information about the assessment of affinity purified nicotinic acetylcholine receptor (nAChR rich membrane solubilized with long chain (16 saturated carbons lysophospholipid with glycerol headgroup (LFG-16. The assessment of stability and functionality of solubilized membrane protein is a critical step prior to further crystallization trails. One of the key factors for this task is the appropriate choice of a detergent that can support nAChR activity and stability comparable to the crude membranes. The stability of the nAChR-LFG-16 complex incorporated into lipid cubic phase (LCP was monitored for a period of 30 days by means of fluorescence recovery after photobleaching (FRAP and the functionality was evaluated after its incorporation into Xenopus oocyte by means of the two electrode voltage clamp technique. Keywords: Detergents, Fluorescence recovery after photobleaching, Lipidic Cubic Phase, nAChR, Planar lipid bilayer, Two-electrode voltage clamp

Status of coastal forests of the Northern Sumatra in 2005 (after 2004’s tsunami catastrophe

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ONRIZAL

2016-04-01

Full Text Available Abstract. Onrizal, Mansor M. 2015. Status of coastal forests of the Northern Sumatra in 2005 (after 2004’s tsunami catastrophe. Biodiversitas 17: 44-54. The first intensive ecological study of coastal vegetation including mangrove, littoral and peat swamp forests after the 2004 tsunami catastrophe in Northern Sumatra was conducted from January to December 2005 where 16 sampling sites along 2960km coastline in Northern Sumatra were selected. In each site, one quadrat of 100 m x 100 m was established and divided into 10 m x 10 m subplots where all standing trees of ≥ 2 cm diameter at breast height (DBH were identified to species level and measured. Overall 54,871 standing trees were recorded in 16 sites comprising 84 species in 65 genera and 37 families. Mangrove trees Rhizophora apiculata and R. mucronata were widely distributed and are dominant in most of the sampling sites. This indicated that these species have stronger resilient compared to other species. The highest value of Shannon-Wiener index of species and Evenness index of species was 3.03 and 0.85, respectively. It means that some sites were rich in biodiversity which harbors various species of plants. Subsequently, undisturbed coastal forests including mangroves, littoral forests and peat swamp forests characterized by dense stands, mixed species and structures play an important role in coastal protection against tsunami. Therefore, the coastal vegetation is needed to conserve the biodiversity and to maintain the production capacity as part of sustainable and longlasting vegetation bioshield.

Confirming a Role for α9nAChRs and SK Potassium Channels in Type II Hair Cells of the Turtle Posterior Crista

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Xiaorong Xu Parks

2017-11-01

Full Text Available In turtle posterior cristae, cholinergic vestibular efferent neurons (VENs synapse on type II hair cells, bouton afferents innervating type II hair cells, and afferent calyces innervating type I hair cells. Electrical stimulation of VENs releases acetylcholine (ACh at these synapses to exert diverse effects on afferent background discharge including rapid inhibition of bouton afferents and excitation of calyx-bearing afferents. Efferent-mediated inhibition is most pronounced in bouton afferents innervating type II hair cells near the torus, but becomes progressively smaller and briefer when moving longitudinally through the crista toward afferents innervating the planum. Sharp-electrode recordings have inferred that efferent-mediated inhibition of bouton afferents requires the sequential activation of alpha9-containing nicotinic ACh receptors (α9*nAChRs and small-conductance, calcium-dependent potassium channels (SK in type II hair cells. Gradations in the strength of efferent-mediated inhibition across the crista likely reflect variations in α9*nAChRs and/or SK activation in type II hair cells from those different regions. However, in turtle cristae, neither inference has been confirmed with direct recordings from type II hair cells. To address these gaps, we performed whole-cell, patch-clamp recordings from type II hair cells within a split-epithelial preparation of the turtle posterior crista. Here, we can easily visualize and record hair cells while maintaining their native location within the neuroepithelium. Consistent with α9*nAChR/SK activation, ACh-sensitive currents in type II hair cells were inward at hyperpolarizing potentials but reversed near −90 mV to produce outward currents that typically peaked around −20 mV. ACh-sensitive currents were largest in torus hair cells but absent from hair cells near the planum. In current clamp recordings under zero-current conditions, ACh robustly hyperpolarized type II hair cells. ACh

PERATURAN-PERATURAN DAERAH BERMUATAN MATERI AJARAN ISLAM DI SUMATERA SELATAN

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Yazwardi Yazwardi

2016-12-01

Full Text Available Indonesia as a country that consists of areas in the various islands with mileage close of central administration necessitates the existence of local governance as mandated in Article 18 of the Constitution NRI 1945. Local regulations  as an operational basis for carrying out local government administration functions and is part of a systematic law in Indonesia has a very significant role in regulating the life of the nation. Regional Regulation of the substance often causes controversy and resistance from various academics and social groups of society when loading material and the teaching of religious values. Some local regulations in South Sumatra Province who allegedly charged material Islamic teachings do not bring social problems because the material in parallel with its cargo historical circumstances, sociological, anthropological and demographic factors people of South Sumatra.

Substituting Wheat Flour with Banana Skin Flour from Mixture Various Skin Types of Banana on Making Donuts

OpenAIRE

Renny Futeri; Pharmayeni Pharmayeni

2014-01-01

Tropical forest plants is a very rich source of chemical compounds or bioactive efficacious . Many of the compounds potential as a source of raw materials in food processing . One is the banana plant , West Sumatra Padang and Bukittinggi is one area in Indonesia with banana . Generally people in West Sumatra just consume or eat the fruit and throw banana skin just because it is considered as waste ( waste banana peel ) . When the banana peel waste is left alone so do not rule out the possibil...

Biallelic mutation of UNC50, encoding a protein involved in AChR trafficking, is responsible for arthrogryposis.

Science.gov (United States)

Abiusi, Emanuela; D'Alessandro, Manuela; Dieterich, Klaus; Quevarec, Loic; Turczynski, Sandrina; Valfort, Aurore-Cecile; Mezin, Paulette; Jouk, Pierre Simon; Gut, Marta; Gut, Ivo; Bessereau, Jean Louis; Melki, Judith

2017-10-15

Arthrogryposis multiplex congenita (AMC) is a developmental condition characterized by multiple joint contractures resulting from reduced or absent fetal movements. Homozygosity mapping of disease loci combined with whole exome sequencing in a consanguineous family presenting with lethal AMC allowed the identification of a homozygous frameshift deletion in UNC50 gene (c.750_751del:p.Cys251Phefs*4) in the index case. To assess the effect of the mutation, an equivalent mutation in the Caenorhabditis elegans orthologous gene was created using CRISPR/Cas9. We demonstrated that unc-50(kr331) modification caused the loss of acetylcholine receptor (AChR) expression in C. elegans muscle. unc-50(kr331) animals were as resistant to the cholinergic agonist levamisole as unc-50 null mutants suggesting that AChRs were no longer expressed in this animal model. This was confirmed by using a knock-in strain in which a red fluorescent protein was inserted into the AChR locus: no signal was detected in unc-50(kr331) background, suggesting that UNC-50, a protein known to be involved in AChR trafficking, was no longer functional. These data indicate that biallelic mutation in the UNC50 gene underlies AMC through a probable loss of AChR expression at the neuromuscular junction which is essential for the cholinergic transmission during human muscle development. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Zonal asymmetry of daytime 150-km echoes observed by Equatorial Atmosphere Radar in Indonesia

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T. Yokoyama

2009-03-01

Full Text Available Multi-beam observations of the daytime ionospheric E-region irregularities and the so-called 150-km echoes with the 47-MHz Equatorial Atmosphere Radar (EAR in West Sumatra, Indonesia (0.20° S, 100.32° E, 10.36° S dip latitude are presented. 150-km echoes have been frequently observed by the EAR, and their characteristics are basically the same as the equatorial ones, except for an intriguing zonal asymmetry; stronger echoes in lower altitudes in the east directions, and weaker echoes in higher altitudes in the west. The highest occurrence is seen at 5.7° east with respect to the magnetic meridian, and the altitude gradually increases as viewing from the east to west. Arc structures which return backscatter echoes are proposed to explain the asymmetry. While the strength of radar echoes below 105 km is uniform within the wide coverage of azimuthal directions, the upper E-region (105–120 km echoes also show a different type of zonal asymmetry, which should be generated by an essentially different mechanism from the lower E-region and 150-km echoes.

Paleogene Sediment Character of Mountain Front Central Sumatra Basin

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P. A. Suandhi

2014-07-01

Full Text Available DOI: 10.17014/ijog.v8i3.164The SE-NW trending Mountain Front of Central Sumatra Basin is located in the southern part of the basin. The Mountain Front is elongated parallel to the Bukit Barisan Mountain, extending from the Regencies of North Padang Lawas (Gunung Tua in the northwest, Rokan Hulu, Kampar, Kuantan Singingi, and Inderagiri Hulu Regency in the southeast. The Palaeogene sediments also represent potential exploration objectives in Central Sumatra Basin, especially in the mountain front area. Limited detailed Palaeogene sedimentology information cause difficulties in hydrocarbon exploration in this area. Latest age information and attractive sediment characters based on recent geological fieldwork (by chaining method infer Palaeogene sediment potential of the area. The Palaeogene sedimentary rock of the mountain front is elongated from northwest to southeast. Thickness of the sedimentary unit varies between 240 - 900 m. Palynology samples collected recently indicate that the oldest sedimentary unit is Middle Eocene and the youngest one is Late Oligocene. This latest age information will certainly cause significant changes to the existing surface geological map of the mountain front area. Generally, the Palaeogene sediments of the mountain front area are syn-rift sediments. The lower part of the Palaeogene deposit consists of fluvial facies of alluvial fan and braided river facies sediments. The middle part consists of fluvial meandering facies, lacustrine delta facies, and turbidity lacustrine facies sediments. The upper part consists of fluvial braided facies and transitional marine facies sediments. Volcanism in the area is detected from the occurrence of volcanic material as lithic material and spotted bentonite layers in the middle part of the mountain front area. Late rifting phase is indicated by the presence of transitional marine facies in the upper part of the Palaeogene sediments.

Kedudukan Musyawarah dan Demokrasi di Indonesia

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Muhammad Hanafi

2016-04-01

Full Text Available Abstrak: Kedudukan Musyawarah dan Demokrasi di Indonesia. Negara Kesatuan Republik Indonesia (NKRI berdasarkan lintasan sejarah perjuangan, memiliki konstruksi kenegaraan satu-satunya di dunia yang bangsa terlahir dahulu, kemudian baru membentuk negara. Presiden pertama Republik Indonesia Ir. Soekarno menegaskan, bahwa Negara Kesatuan ialah Negara Kebangsaan. Tujuan Bangsa Indonesia terlahir, merdeka, dan membentuk negara memiliki satu cita-cita, Kehendak Untuk Mengangkat Harkat dan Martabat Hidup Rakyat Indonesia (Kedaulatan Rakyat Indonesia. Melalui analisis atas realitas kehidupan saat ini, Bangsa Indonesia telah hidup pada kondisi tatanan kehidupan seolah-olah sama dengan Negara Demokrasi, ialah negara dulu terbentuk baru bangsanya dilahirkan kemudian. Sehingga kedaulatan rakyat Indonesia yang berdasarkan prinsip musyawara-mufakat dan perwakilan belum mampu terealisasi. Sementara pelaksanaan demokrasi voting yang memiliki dasar liberalisme terus bergulir, sehingga kehidupan bangsa Indonesia semakin jauh dari cita-cita awal. DOI: 10.15408/jch.v1i2.2657

Expansion of oil palm and other cash crops causes an increase of the land surface temperature in the Jambi province in Indonesia

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C. R. Sabajo

2017-10-01

Full Text Available Indonesia is currently one of the regions with the highest transformation rate of land surface worldwide related to the expansion of oil palm plantations and other cash crops replacing forests on large scales. Land cover changes, which modify land surface properties, have a direct effect on the land surface temperature (LST, a key driver for many ecological functions. Despite the large historic land transformation in Indonesia toward oil palm and other cash crops and governmental plans for future expansion, this is the first study so far to quantify the impacts of land transformation on the LST in Indonesia. We analyze LST from the thermal band of a Landsat image and produce a high-resolution surface temperature map (30 m for the lowlands of the Jambi province in Sumatra (Indonesia, a region which suffered large land transformation towards oil palm and other cash crops over the past decades. The comparison of LST, albedo, normalized differenced vegetation index (NDVI and evapotranspiration (ET between seven different land cover types (forest, urban areas, clear-cut land, young and mature oil palm plantations, acacia and rubber plantations shows that forests have lower surface temperatures than the other land cover types, indicating a local warming effect after forest conversion. LST differences were up to 10.1 ± 2.6 °C (mean ± SD between forest and clear-cut land. The differences in surface temperatures are explained by an evaporative cooling effect, which offsets the albedo warming effect. Our analysis of the LST trend of the past 16 years based on MODIS data shows that the average daytime surface temperature in the Jambi province increased by 1.05 °C, which followed the trend of observed land cover changes and exceeded the effects of climate warming. This study provides evidence that the expansion of oil palm plantations and other cash crops leads to changes in biophysical variables, warming the land surface and thus

Evaluation of environmental effect of coal stockpile in Muara Telang, Banyuasin, Indonesia

Science.gov (United States)

Rusdianasari; Arita, Susila; Ibrahim, Eddy; Ngudiantoro

2013-04-01

Stockpile commonly serves as a temporary dump before the coal is transported through the waterways. This study investigated the effects of coal stockpiles on the surrounding environment: air, water, and soil. The location of the study is in the estuary of Telang, South-Sumatra, Indonesia, which is located at the edge of the river of Telang and close to the residential community. The monitoring of the environmental impact from the stockpile is intended to conduct an environmental assessment owing the existence and operations of coal accumulation. Enviromental impact analysis was conducted based on the value of the effluent, air pollution (dust), soil and water by determining the parameters of the coal wastewater pH, total suspended solid, ferrous dan ferrous metals contents. The results indicate that the total suspended particulate, total suspended solids, noise level, ferrous metal and manganese metal were 10-14 μg/Nm3 249-355 mg/L, 41.3 to 50.3 dBA, 6.074 to7.579 mg/L, and 1.987 to 2.678 mg/L, respectively. Meanwhile the pH of water and soil were 3 to 4 and 2.83 to 4.02 respectively. It is concluded that the pH value are beyond the threshold standard.

Evaluation of environmental effect of coal stockpile in Muara Telang, Banyuasin, Indonesia

International Nuclear Information System (INIS)

Rusdianasari; Arita, Susila; Ibrahim, Eddy; Ngudiantoro

2013-01-01

Stockpile commonly serves as a temporary dump before the coal is transported through the waterways. This study investigated the effects of coal stockpiles on the surrounding environment: air, water, and soil. The location of the study is in the estuary of Telang, South-Sumatra, Indonesia, which is located at the edge of the river of Telang and close to the residential community. The monitoring of the environmental impact from the stockpile is intended to conduct an environmental assessment owing the existence and operations of coal accumulation. Enviromental impact analysis was conducted based on the value of the effluent, air pollution (dust), soil and water by determining the parameters of the coal wastewater pH, total suspended solid, ferrous dan ferrous metals contents. The results indicate that the total suspended particulate, total suspended solids, noise level, ferrous metal and manganese metal were 10-14 μg/Nm 3 249-355 mg/L, 41.3 to 50.3 dBA, 6.074 to7.579 mg/L, and 1.987 to 2.678 mg/L, respectively. Meanwhile the pH of water and soil were 3 to 4 and 2.83 to 4.02 respectively. It is concluded that the pH value are beyond the threshold standard.

Repeated administration of alpha7 nicotinic acetylcholine receptor (nAChR) agonists, but not positive allosteric modulators, increases alpha7 nAChR levels in the brain

DEFF Research Database (Denmark)

Christensen, Ditte Z; Mikkelsen, Jens D; Hansen, Henrik H

2010-01-01

The alpha7 nicotinic acetylcholine receptor (nAChR) is an important target for treatment of cognitive deficits in schizophrenia and Alzheimer's disease. However, the receptor desensitizes rapidly in vitro, which has led to concern regarding its applicability as a clinically relevant drug target...

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African Journals Online (AJOL)

2018-01-15

Jan 15, 2018 ... (tires, clutch, brakes wear and tear producing by-product of particulate) [7-8]. ... originated from biomass and forest fires in Indonesia (Sumatra and Kalimantan) for .... Car/MPV/Van 2 axles (3 or 4 wheels- exclude taxis ). 0.015.

Efisiensi Perusahaan Crude Palm Oil (CPO di Indonesia

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Amzul Rifin

2017-07-01

Full Text Available Crude Palm Oil (CPO is an important Indonesian agricultural product as a raw material for cooking oil and an export commodity. In order to achieve maximum profit, the companies producing the CPO need to produce it efficiently. This study used the data from the 2013 Annual Manufacturing Survey conducted by the Statistics Indonesia. In this survey, there were 547 factories producing CPO. The efficiency measurement utilized the Data Envelopment Analysis (DEA approach using value of production as the output and two inputs, namely the number of workers and raw material value. The results showed that there are 17 factories out of 547 factories which are efficient indicated by the efficiency value of one. Factories owned by the private national companies have the highest average of efficiency followed by the foreign and government-owned companies. In regards to location, factories located in Kalimantan Island have higher average efficiency compared to those located in Sumatra Island and other islands. Meanwhile, factories with local market orientation have a higher efficiency compared to those with export market orientation.Keywords: CPO, efficiency, data envelopment analysis (DEAABSTRAKCrude Palm Oil (CPO merupakan salah satu andalan produk pertanian Indonesia baik sebagai bahan baku minyak goreng maupun komoditas ekspor. Untuk mencapai keuntungan maksimum, maka perusahaan penghasil CPO perlu berproduksi secara efisien. Penelitian ini menggunakan data-data perusahaan sawit yang berasal dari Survei Perusahaan Industri Manufaktur 2013 yang dilakukan oleh Badan Pusat Statistik. Pada survei ini terdapat 547 pabrik yang merupakan penghasil CPO. Pengukuran efisiensi menggunakan analisis Data Envelopment Analysis (DEA dengan satu output, yaitu nilai produksi serta dua input, yaitu jumlah pekerja dan nilai bahan baku. Hasil yang diperoleh menunjukkan dari 547 perusahaan terdapat 17 perusahaan yang efisien yang ditunjukkan oleh nilai efisiensi sebesar satu

Indonesia`s Palm Oil Industrialization: the Resistance of Tanjung Pusaka Villagers, Central Kalimantan Against Palm Oil Industry

OpenAIRE

Wulansari, Ica

2017-01-01

Indonesia`s Palm oil industry is the greatest export commodity in the world. Palm oil industry has been developed since Soeharto`s administration with World Bank`s initiative. Indonesia`s development pattern is modernization which is fully supported by global capitalist agent. Furthermore, the government of Indonesia has issued policies to support this industry and the ease of accessibilty for investor to build in Indonesia. Most of the policies focus on economic interest with lack of attenti...

Deposition and characterisation of multilayer hard coatings. Ti/TiNδ/TiCxNy/(TiC) a-C:H/(Ti) a-C:H

International Nuclear Information System (INIS)

Burinprakhon, T.

2001-02-01

Multilayer hard coatings containing Ti, TiNδ, TiC x N y , (TiC m ) a-C:H, (TiC n ) a-C:H, and (Ti) a-C:H were deposited on commercially pure titanium substrates by using an asymmetric bipolar pulsed-dc reactive magnetron sputtering of a titanium target, with Ar, Ar+N 2 , Ar+N 2 +CH 4 , and Ar+CH 4 gas mixtures. The microstructures, elemental compositions and bonding states of the interlayers and the coating surfaces were studied by using cross-sectional transmission electron microscopy (XTEM), electron energy loss spectroscopy (EELS), X-ray diffraction (XRD), Raman spectroscopy, and X-ray photoelectron spectroscopy (XPS). The microstructure development of the multilayer coating was strongly influenced by target poisoning. As a result of the complete poisoning of the titanium target during the deposition of TiNδ and TiC x N y interlayers, the a-C:H interlayers containing graded titanium and nitrogen contents were found to develop successively to the TiC x N y interlayer without the formation of near-stoichiometric TiC. The (TiC m ) a-C:H interlayer consisted of nano-particles of distorted fcc crystal structure embedded in the a-C:H matrix. The (TiC n ) a-C:H and (Ti) a-C:H top layers were found to be a-C:H matrix without nano-particles. In the (Ti) a-C:H top layer there was no measurable amount of Ti observed, regardless of the variation of CH 4 concentration between 37.5 and 60 % flow rate in Ar+-CH4 gas mixture. The top layer (Ti) a-C:H was found to contain approximately 10 atomic % nitrogen, due to N 2 contamination during deposition caused by low conductance of N 2 through the nominally closed valve of the mass flow controller. The change of the CH 4 concentration during deposition of the top layer (Ti) a-C:H, however, showed a strong influence on the hydrogen content. The comparison of the fluorescence background of the Raman spectra revealed that hydrogen-less (Ti) a-C:H was deposited at a CH 4 concentration of less than 50 % flow rate in Ar. The hardness

Parameters Affecting Household Income Diversity of Farmer’s Tribes in South Sumatra Tidal Wetland

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Elisa Wildayana

2016-12-01

Full Text Available The research aimed to determine parameters affecting household income diversity of farmer’s tribes in South Sumatra tidal wetland, especially studied from the aspect of land acreage, education level, age of farmers and tribes of farmers. The research was using survey method and carried out from June-August 2016 in the Delta Telang I Banyuasin, South Sumatra. The data were recorded by questionnaire for 145 respondents of farmers. Data was processed, described and correlated to see the relevance of the parameters with other parameters. The research concluded that the character of household economy of farmers explaining the relation between production decisions to increase rice production is land acreage, education, age, experience of farmers, number of household members, and labor allocation. Multi commodities farming (rice and plantation was very favorable compared to monoculture rice fields? But this is a little bit contradictive with government policy that the research area is pointed out as the center of rice production. Therefore, government policy needs to motivate farmers that they can manage their farming from upstream to downstream and they work full in their own farming. The government policy should be site-specific and appropriated with the tribes of farmers

The relationship of reports of aches and joint pains to the menopausal transition: a longitudinal study.

Science.gov (United States)

Szoeke, C E; Cicuttini, F M; Guthrie, J R; Dennerstein, L

2008-02-01

OBJECTIVES Part I: To determine factors associated with reported joint symptoms across the menopausal transition. Part II: To investigate the relationship between symptom reporting and radiological arthritis in postmenopausal women. DESIGN Part I: The Melbourne Women's Mid-life Health Project, commenced in 1991, is a population-based prospective study of 438 Australian-born women, aged 45-55 years and menstruating at baseline; they were interviewed annually over 8 years. The retention rate was 88% (n = 387). Part II: After 12 years of follow-up, 257 (57%) women returned for assessment and 224 agreed to undergo X-rays of their hands and knees. METHODS Part I: Annual fasting blood collection, physical measurements, and interviews including questions about bothersome aches or stiff joints in the previous 2 weeks. A score for this symptom was calculated from the product of the severity and frequency data. These data were analyzed using random-effects time-series regression models. Part II: X-rays were scored for evidence of osteoarthritis using a validated scale, by two investigators who were blinded to questionnaire results. RESULTS Part I: 'Aches and stiff joints' were the most commonly reported symptom and reporting increased over time in the longitudinal study. Variables significantly associated with reporting bothersome aches and stiff joints were high body mass index (BMI) (p Part II: The relationship between radiological osteoarthritis and symptom reports approached statistical significance (p = 0.06). Knee osteoarthritis was significantly associated with symptom reports (p = 0.008) but not hand osteoarthritis (p = 0.2). Menopausal status, BMI, employment status and depressed mood were all associated with the experience of bothersome aches and stiff joints. Aches and stiff joints, common in postmenopausal women, are not necessarily indicative of radiological osteoarthritis.

Peran Serikat Buruh Migran Indonesia dalam Melindungi Hak Tenaga Kerja Indonesia di Luar Negeri

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Fenny Sumardiani

2014-12-01

Full Text Available Permasalahan yang dihadapi Tenaga Kerja Indonesia baik pada fase pra penempatan, selama masa penempatan sampai dengan pasca penempatan dari waktu ke waktu perlu diperbaiki karena memang sangat luas dan membutuhkan koordinasi banyak pihak baik Pemerintah, PPTKIS, maupun organisasi yang membantu menyuarakan hak Tenaga Kerja Indonesia yang biasa disebut dengan Serikat Buruh Migran Indonesia dan Tenaga Kerja Indonesia itu sendiri. Koordinasi yang dimaksudkan terutama adalah dalam melindungi hak Tenaga Kerja Indonesia yang bermasalah. Penelitian ini bertujuan untuk menganalisis peran Serikat Buruh Migran Indonesia dalam melindungi Hak Tenaga Kerja Indonesia yang bermasalah di Kabupaten Kendal serta kendala yang dihadapi Serikat Buruh Migran dalam memperjuangkan hak-hak TKI yang bermasalah di Kabupaten Kendal serta serta upaya apa yang dilakukan untuk mengatasi kendala tersebut. Metode yang digunakan dalam penelitian ini adalah metode pendekatan yuridis sosiologis dengan metode analisa data kualitatif. Hasil penelitian ini menunjukan bahwa peran Serikat Buruh Migran Indonesia dalam menagani masalah TKI dengan memberikan pendampingan kepada tenaga kerja indonesia dan keluarganya yang mengalami masalah pada saat bertugas maupun purna tugas; memberikan pendidikan kritis; memberikan pemberdayaan ekonomi dalam peningkatan kesejahteraan bagi para anggota dan keluarganya; memberikan pelatihan bagi para tenaga kerja indonesia yang sudah kembali ke indonesia. The problem faced by Indonesian Manpower both the phase pre placement, during placement until after placement from time to time need to be fixed because it is very broad and requires coordination of many parties, both Governments, PPTKIS, as well as organizations that help expressing the rights of Indonesian Workers usual called the Indonesian Migrant Workers Union and Labour Indonesia itself. Coordination is intended primarily to protect the rights of Indonesian Workers are problematic. This study aims

Efficient expression of functional (α6β22β3 AChRs in Xenopus oocytes from free subunits using slightly modified α6 subunits.

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Carson Kai-Kwong Ley

Full Text Available Human (α6β2(α4β2β3 nicotinic acetylcholine receptors (AChRs are essential for addiction to nicotine and a target for drug development for smoking cessation. Expressing this complex AChR is difficult, but has been achieved using subunit concatamers. In order to determine what limits expression of α6* AChRs and to efficiently express α6* AChRs using free subunits, we investigated expression of the simpler (α6β22β3 AChR. The concatameric form of this AChR assembles well, but is transported to the cell surface inefficiently. Various chimeras of α6 with the closely related α3 subunit increased expression efficiency with free subunits and produced pharmacologically equivalent functional AChRs. A chimera in which the large cytoplasmic domain of α6 was replaced with that of α3 increased assembly with β2 subunits and transport of AChRs to the oocyte surface. Another chimera replacing the unique methionine 211 of α6 with leucine found at this position in transmembrane domain 1 of α3 and other α subunits increased assembly of mature subunits containing β3 subunits within oocytes. Combining both α3 sequences in an α6 chimera increased expression of functional (α6β22β3 AChRs to 12-fold more than with concatamers. This is pragmatically useful, and provides insights on features of α6 subunit structure that limit its expression in transfected cells.

Individual and contextual variation in Thomas langur male loud calls

NARCIS (Netherlands)

Wich, S.A.; Koski, S.; Vries, Han de; Schaik, Carel P. van

2003-01-01

Individual and contextual differences in male loud calls of wild Thomas langurs (Presbytis thomasi) were studied in northern Sumatra, Indonesia. Loud calls were given in the following contexts: morning calls, vocal responses to other groups, between-group encounter calls and alarmcalls. Loud

The Role of nAChR and Calcium Signaling in Pancreatic Cancer Initiation and Progression

Energy Technology Data Exchange (ETDEWEB)

Schaal, Courtney [Department of Tumor Biology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612 (United States); Padmanabhan, Jaya [Department of Molecular Medicine and USF Health Byrd Alzheimer’s Institute, University of South Florida, 4001 E. Fletcher Ave., Tampa, FL 33612 (United States); Chellappan, Srikumar, E-mail: Srikumar.Chellappan@moffitt.org [Department of Tumor Biology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612 (United States)

2015-07-31

Pancreatic cancer shows a strong correlation with smoking and the current therapeutic strategies have been relatively ineffective in improving the survival of patients. Efforts have been made over the past many years to understand the molecular events that drive the initiation and progression of pancreatic cancer, especially in the context of smoking. It has become clear that components of tobacco smoke not only initiate these cancers, especially pancreatic ductal adenocarcinomas (PDACs) through their mutagenic properties, but can also promote the growth and metastasis of these tumors by stimulating cell proliferation, angiogenesis, invasion and epithelial-mesenchymal transition. Studies in cell culture systems, animal models and human samples have shown that nicotinic acetylcholine receptor (nAChR) activation enhances these tumor-promoting events by channeling signaling through multiple pathways. In this context, signaling through calcium channels appear to facilitate pancreatic cancer growth by itself or downstream of nAChRs. This review article highlights the role of nAChR downstream signaling events and calcium signaling in the growth, metastasis as well as drug resistance of pancreatic cancer.

The Role of nAChR and Calcium Signaling in Pancreatic Cancer Initiation and Progression

International Nuclear Information System (INIS)

Schaal, Courtney; Padmanabhan, Jaya; Chellappan, Srikumar

2015-01-01

Pancreatic cancer shows a strong correlation with smoking and the current therapeutic strategies have been relatively ineffective in improving the survival of patients. Efforts have been made over the past many years to understand the molecular events that drive the initiation and progression of pancreatic cancer, especially in the context of smoking. It has become clear that components of tobacco smoke not only initiate these cancers, especially pancreatic ductal adenocarcinomas (PDACs) through their mutagenic properties, but can also promote the growth and metastasis of these tumors by stimulating cell proliferation, angiogenesis, invasion and epithelial-mesenchymal transition. Studies in cell culture systems, animal models and human samples have shown that nicotinic acetylcholine receptor (nAChR) activation enhances these tumor-promoting events by channeling signaling through multiple pathways. In this context, signaling through calcium channels appear to facilitate pancreatic cancer growth by itself or downstream of nAChRs. This review article highlights the role of nAChR downstream signaling events and calcium signaling in the growth, metastasis as well as drug resistance of pancreatic cancer

EKSPEKTASI PERTUMBUHAN EKONOMI SUMATERA BARAT DAN TANTANGAN PEREKONOMIAN TAHUN 2015

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Ansofino

2015-03-01

Full Text Available Abstract The focus of study are the problem economic of growth of west Sumatra and economic of challenge among globall economic of crisis. The aim of research are the forcasting and formulated of economic growth of West Sumatra in 2015 to determine of direction economic development in the future. The research used econometric method and times series data. Result of research showed are economic growth of West Sumatra on 2013 experience contraction from 6.35% in 2012 straight slowdown become 6.13% and continue contraction until 2014 attained 5.93%, be going on with national economic condition which also experience growth slowdown in 2013 only attained 5,8%, indeed the World Bank forecast (on Mart 2014 national economic growth in 2014 later only attained 5.3% and forcasting by Indonesia central bank immediatly descend until the first quartal 2014. Economic growth of West Sumatra approximately 2015 estimating about 5.8% until 6.2%. Keywords: Economic growth of expectation, economic challenge Abstrak

Myths and stereotypes about adat law: A reassessment of Van Vollenhoven in the light of current struggles over adat law in Indonesia

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Keebet von Benda-Beckmann

2011-09-01

Full Text Available Recent analyses of the ‘revitalisation of tradition’ have rekindled earlier discussions of the ‘creation of customary law’ in colonial states. For Indonesia, critics have deconstructed a ‘myth of adat’, arguing that adat law was an invention of the adat law scholar Van Vollenhoven and his followers. The assessment of that period also shapes interpretations of developments in Indonesia after 1998. The purpose of this paper is to demonstrate that in some respects the critique of colonial scholarship was misconceived, and that these misconceptions hamper a proper understanding of the current revitalisation of adat in Indonesia. Many interpretations of colonial legal science and practice have become anachronistic and stereotypical. We argue that most interpretations were and are largely based on a legalistic conception of ‘law’ and ‘customary law’, that authors selectively generalise interpretations from specific contexts, and that they do not take into account what such interpretations say over legal realities beyond these contexts. Lastly we think that the target of the critique is somewhat misconceived as it is directed at those scholars who were aware of the danger of legal ethnocentrism and criticised it, while not looking at those colonial scholars and courts, who grossly misinterpreted local normative systems in terms of Dutch legal categories. We argue that some assumptions and propositions of these earlier and contemporary critical deconstructions are in need of re-evaluation. Given its presence in current analyses, reconsidering Van Vollenhoven and his followers is more than a return to a history long gone by. We substantiate our propositions with a discussion of the history of the village commons, ulayat, in West Sumatra, which has always been a central illustration in all discussions of adat law.

Throat ache ans swelling of the neck: first symptoms of Lemierre's syndrome

NARCIS (Netherlands)

de Lange, J.; Ybema, A; Baas, E. M.

2014-01-01

Lemierre's syndrome, a thrombophlebitis of the internal jugular vein, is a rare disorder, usually caused by the microorganism Fusobacterium necrophorum. Throat ache and swelling of the neck are often the first symptoms. Without adequate treatment, Lemierre's syndrome may result in thrombosis of the

Konstruksi Pencitraan Maskulinitas pada Majalah Men's Health Indonesia Versus Feminitas pada Majalah Women's Health Indonesia

OpenAIRE

Azis, Andi Azisah; Cangara, Hafied; Bahfiarti, Tuti

2015-01-01

The aim of the research was to determine the construction of image projection of masculinity formed Indonesia Men's Health magazine versus femininity of Indonesia Women's Health magazine. The subjects of the research were the covers of Indonesia Men's Health magazine and Indonesia Women's Health magazine published from December 2014 to May 2015. The methods of obtaining the data were done by interpreting picture texts and categorizing written text topics. They were analyzed descriptive qualit...

Analisis Determinan Net Ekspor Indonesia

OpenAIRE

Daulay, Rahmawaty

2010-01-01

This study is to analyzing empirically among Indonesia GDP, trade partnership GDP (Malaysia, Singapore, US and Thailand) and real exchange rate toward Indonesia Net Export. To find out which one from those three variables is significant in order to fluctuating (increasing or decreasing) Indonesia Net Export either in the short run or in the long run. Data collection is obtained using secondary data, namely Indonesia GDP, Malaysia GDP, Singapura GDP, US GDP, Thailand GDP and real exchange rate...

EKSISTENSI BAHASA INDONESIA SEBAGAI BAHASA PERSATUAN

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Marsudi Marsudi

2008-11-01

Full Text Available Bahasa Indonesia lahir dari Bahasa Melayu yang pada zaman dulu menjadi bahasa lingua franca, yakni bagasa perdagangan antarpulau di nusantara. Kemudian dikukuhkan menjadi bahasa persatuan melalui momen Sumpah Pemuda. Bahasa Melayu menjadi dominan di kala itu dikarenakan fleksibelitasnya akan bahasa-bahasa lain. Dengan fakta tersebut, tepatnya 28 Oktober 1928, bahasa Melayu diangkat sebagai bahasa persatuan dan tahun 1945 diresmikan sebagai bahasa negara. Permasalahan yang muncul dalam eksistensi bahasa Indonesia adalah bagaimanakah cara mempertahankan eksistensi bahasa Indonesia? Tidak hanya masalah eksistensi saja, tetapi sanggupkah bahasa-bahasa daerah di negeri ini memperkaya kosa kata dan istilah bahasa Indonesia? Selain itu, bagaimanakah potensi bahasa Indonesia di era globalisasi? Eksistensi bahasa Indonesia, selain dipengaruhi kekonsistenan penggunaanya, juga didukung oleh kemampuan bahasa tersebut dalam mengungkapkan fenomena baru yang berkembang. Oleh karena itu, perkembangan bahasa Indonesia sangat tergantung pada tingkat keberhasilan menciptakan kosa kata dan istilah-istilah baru. Bahasa Indonesia sudah mulai mengglobal karena bahasa Indonesia memiliki sifat terbuka dan demokratis. Perkembangan yang terjadi sekarang dan yang datang tidak hanya menyangkut masalah struktur dan bahasa, tetapi lebih jauh mengungkapkan permasalahan manusia baru yang dialami manusia di dalam sebuah proses perubahan dalam berbagai aspek kehidupan

Contesting sharia : state law, decentralization and Minangkabau custom

NARCIS (Netherlands)

Huda, Yasrul

2013-01-01

This book explains how Sharia, commonly called Perda Sharia (Sharia by-law) in Indonesia, was legislated on the provincial, regional and municipal level in West Sumatra. This process began after the government started a decentralization policy in 2000. Although the law of local autonomy prescribes

Development of radiohalogenated muscarinic ligands for the in vivo imaging of m-AChR by nuclear medicine techniques

Energy Technology Data Exchange (ETDEWEB)

McPherson, D.W.; Luo, H.; Knapp, F.F. Jr.

1994-06-01

Alterations in the density of acetylcholinergic muscarinic receptors (m-AChR) have been observed in various dementias. This has spurred interest in the development of radiohalogenated ligands which can be used for the non-invasive in vivo detection of m-AChR by nuclear medicine techniques. We have developed a new ligand 1-azabicyclo[2.2.2]oct-3-yl ({alpha}-hydroxy-{alpha}-(1-iodo-1-propen-3-yl)-{alpha}-phenylacetate (IQNP,12) which demonstrates high affinity for the muscarinic receptor. When labeled with radioiodine it has been shown to be selective and specific for m-ACHR. Initial studies on the separation and in vivo evaluation of the various isomers of IQNP have shown that the stereochemistry of the chiral centers and the configuration around the double bond play an important role in m-AChR subtype specificity. In vivo evaluation of these stereoisomers demonstrate that E-(R,R)-IQNP has a high affinity for the M{sub 1} muscarinic subtype while Z-(R,R)-IQNP demonstrate a high affinity for M{sub 1} and M{sub 2} receptor subtypes. These data demonstrate IQNP (12) has potential for use in the non-evasive in vivo detection of m-AChR by single photon emission computed tomography (SPECT). A brominated analogue, ``BrQNP,`` in which the iodine has been replaced by a bromine atom, has also been prepared and was shown to block the in vivo uptake of IQNP in the brain and heart and therefore has potential for positron emission tomographic (PET) studies of m-AChR.

The prevalence of anemia in pregnant women and its associated risk factors in North Sumatera, Indonesia

Science.gov (United States)

Lestari, S.; Fujiati, I. I.; Keumalasari, D.; Daulay, M.; Martina, S. J.; Syarifah, S.

2018-03-01

The gestation period is the period that determines the quality of human resources in the future because the development of the child is determined from the time of the fetus in utero. The most common nutrition problems suffered by pregnant women in Indonesia is Chronic Energy Deficiency (CED) and anemia. The aim of this research to determine the prevalence of anemia in pregnant women and the risk factors associated with anemia in urban and rural areas of North Sumatera Province. This research is as descriptive analyticwith cross-sectional approach. Total sample 140 pregnant women from the Medan City, Langkat District and South Labuhan Batu District, and was from June to October 2016. Data collected by using interviews, hemoglobinometer tool and analyzed with Chi-square test. Anemia was in 40.7% of pregnant women, and the incidence of anemia is more common in pregnant women in urban areas than in rural areas. The factors associated with anemia in pregnant women is parity, knowledge of nutrition, diet and the risk of chronic energy deficiency (p anemia in pregnant women in North Sumatra was higher than the national prevalence.

Macro patterns of internal migration in Indonesia, 1971-1990.

Science.gov (United States)

Alatas, S

1993-12-01

Indonesia's population mobility rate is still relatively low. In 1990 only 8.25% of Indonesians lived outside the provinces where they were born. In contrast, according to the US censuses, since the 1870s no fewer than 20% of Americans did. The level of population mobility is even lower for inter-island and interregional migration. In 1990 only 4.29% of Indonesians lived outside their home islands or regions. The level of urbanization has also had an impact, with rural-urban migration increasing from 17.18% in 1971 to 22.38% in 1980, and to 30.93% in 1990. Between 1971 and 1990 the increase amounted to 20.34% in Jakarta, Surbaya, Bandung, Medan, and Semarang. Migration occurs because people want to improve their lives. The reasons for migration include: 1) to continue education, 2) to search for a better job, 3) to obtain better wages or income, 4) to accompany parents or spouse, 5) to secure political support, and 6) to escape from unpleasant conditions. The 1990 census data on migration were derived from 1) province of birth, 2) province of previous residence, 3) duration of residence at the current province, and 4) province of residence 5 years prior to the census. Interprovincial life time migration increased in Indonesia from 5.8 million in 1971 to 10.2 million in 1980 and to 14.8 million in 1990. Most of the provinces of Sumatra and Kalimantan experienced net positive migration in which in-migration exceeded out-migration. On the other hand, migrants from Jakarta to West Java accounted for 75.6% or 794,987 out of the 1,052,234 people who moved out of the capital city. In 1971 as much as 31.18% of migration across provincial borders headed for DKI Jakarta. In 1990 DKI Jakarta and West Java accommodated 37.75% of the interprovincial migrants. Recent in, out, and net migration declined 2.8 million between 1980 and 1985, but it went up to 5.3 million between 1985 and 1990. Between 1985 and 1990 interprovincial migration towards urban areas amounted to 3.2 million

Does Your Patient's Urine Turns Dark? Alkaptonuria and Low Back Ache: A Literature Review.

Science.gov (United States)

Kanniyan, Kalaivanan; Pathak, Aditya C; Dhammi, Ish Kumar; Jain, Anil Kumar

2014-01-01

Alkaptonuria is a very rare inborn error of amino acid metabolism due to deficient homogentisic acid (HGA) oxidase enzyme leading to accumulation of HGA in plasma, cartilage, other tissues of human body and its excretion in urine. It has both systemic and peripheral signs and symptoms. Though low back is a common symptom of alkaptonuria but, in the absence of ochronosis it is rare. Alkaptonuria itself is very rare occurrence with no specific treatment option available to reverse the effect as yet. A 38-year-old male, embroidery worker presented with chronic low back ache with history of staining of clothes in infancy. Later on laboratory and the radiological investigation patient was diagnosed to have alkaptonuria without ochronosis. No other systemic manifestation was present. Patient was treated conservatively and responded well. Though alkaptonuria is a very rare disease, and the occurrence of low back-ache in absence of ochronosis is much rarer. One must be aware of this inborn error of metabolism. Early diagnosis though being "diagnosis of exclusion" for low back-ache, high index of suspicion is advantageous as symptomatic treatment of the alkaptonuria can be initiated and evaluation of other systemic organs can be done in early stages itself.

[Children's and adolescent's use of medicine for aches and psychological problems: secular trends from 1988 to 2006.

DEFF Research Database (Denmark)

Holstein, Bjørn; Andersen, Anette; Due, Pernille

2009-01-01

INTRODUCTION: Medicine use for aches and psychological problems is common among adolescents. Medicines are toxic and may have harmful side effects. It is therefore important to study change over time and patterns of medicine use. The objective of this paper is to describe self-reported medicine use...... for headaches, stomach-aches, difficulties in falling asleep, and nervousness among 11-, 13-, and 15-year-old boys and girls from 1968 to 2006. MATERIAL AND METHODS: The data material is 6 comparable and representative cross-sectional studies of 11-, 13-, and 15-year-olds from 1988, 1991, 1994, 1998, 2002......: There was a significant increase in 11-, 13-, and 15-year-old student's use of medicine for aches and psychological problems from 1988 to 2006. In the same period, there was a decrease in the prevalence of students who reported pains monthly. Udgivelsesdato: 2009-Jan-5...

Earthquakes & Tsunamis flirting with the Ionosphere: the Sumatra gossip !!

Science.gov (United States)

Occhipinti, G.; Coïsson, P.; Rolland, L. M.; Lognonne, P.

2009-12-01

The December 26, 2004 Sumatra Earthquake and the related Indian Ocean Tsunami generated the largest remote sensing data-set observing natural hazards. The observations showed both, ground motion and ocean sea surface displacement, as well as the related strong ionospheric anomalies. Total electron content (TEC) perturbations have been observed on a global scale, using ground-based GPS receivers [DasGupta et al., 2006, Liu et al., 2006b] and dual-frequency altimeters (e.g., Jason-1 and Topex/Poseidon [Artru et al., 2005]); plasma velocity perturbation has been observed by Doppler soundings [Liu et al., 2006b, Occhipinti et al., 2009]. The observed perturbations may be characterized as two different waves: the first one is an atmospheric wave in the acoustic domain induced by propagation of Rayleigh waves on the Earth surface; the second one is a slower atmospheric wave in the gravity domain strongly coupled with the generated tsunami. Both waves are reproduced by our accurate modeling taking into account the earthquake/tsunami-neutral atmosphere coupling at the base of the atmosphere, as well as the neutral-plasma coupling in the overlying ionosphere [Occhipinti et al., 2006, 2006, 2009]. Here we present a review of the ionospheric observations related to the Sumatra event in the light of modeling to deeply investigate the coupling mechanism between Solid-Earth/Ocean/Atmosphere/Ionosphere. The matching between data and modeling opens new perspectives in the solid earth research as well as in the tsunami detection providing a new insight into the role of the remote sensing in the monitoring of natural hazard. [Artru et al., 2005] Geophys. J. Int., 160, 2005 [DasGupta et al., 2006] Earth Planet. Space, 35, 929-959. [Liu et al., 2006a] Geophys. Res. Lett., 33, L02103, 2006. [Liu et al., 2006b] J. Geophys. Res., 111, A05303. [Occhipinti et al., 2006] Geophys. Res. Lett., 33, L20104, 2006 [Occhipinti et al., 2008] Geophys. J. Int., 173, 3, 753-1135, 2008. [Occhipinti et

Morphological characterization of several strains of the rice-pathogenic bacterium Burkholderia glumae in North Sumatra

Science.gov (United States)

Hasibuan, M.; Safni, I.; Lisnawita; Lubis, K.

2018-02-01

Burkholderia glumae is a quarantine seed-borne bacterial pathogen causing panicle blight disease on rice. This pathogen has been detected in some locations in Java, and recently, farmers in North Sumatra have reported rice yield loss with symptoms similar with those on rice infeced by the rice-pathogenic bacterium B. glumae. This research was aimed to isolate several bacterial strains from several rice varieties in various locations in North Sumatra and characterize the morphology of the strains to detect and identify the unknown bacterial strains presumably B. glumae. Several rice seed varieties were collected from Medan and Deli Serdang Districts. The seed samples were extracted, isolated and purified, then grown in semi-selective media PPGA. The morphological characteristics of the bacterial strains were determined including Gram staining, bacterial colony’s and bacterial cell’s morphology. The results showed that of eleven strains isolated, two strains were Gram negative and nine strains were Gram positive. On the basis of colony morphology, all strains had circular form, flat elevation and cream colour while the colony margin varied, i.e. entire and undulate. Most strains had bacillus/rod shape (8 strains) and only 3 strains were coccus.

Aging of oxygen and hydrogen plasma discharge treated a-C:H and ta-C coatings

Energy Technology Data Exchange (ETDEWEB)

Bachmann, Svenja [Physics of Surfaces, Institute of Materials Science, Technische Universität Darmstadt, Alarich-Weiss-Str. 16, 64287 Darmstadt (Germany); BMW Group, Hufelandstraße 4, 80788 Munich (Germany); Schulze, Marcus [Physics of Surfaces, Institute of Materials Science, Technische Universität Darmstadt, Alarich-Weiss-Str. 16, 64287 Darmstadt (Germany); Center of Smart Interfaces, Technische Universität Darmstadt, Alarich-Weiss-Str. 10, 64287 Darmstadt (Germany); Morasch, Jan [Institute of Materials Science, Technische Universität Darmstadt, Surface Science Division, Jovanka-Bonschits-Straße 2, 64287 Darmstadt (Germany); Hesse, Sabine [Physics of Surfaces, Institute of Materials Science, Technische Universität Darmstadt, Alarich-Weiss-Str. 16, 64287 Darmstadt (Germany); Center of Smart Interfaces, Technische Universität Darmstadt, Alarich-Weiss-Str. 10, 64287 Darmstadt (Germany); Hussein, Laith [Eduard-Zintl-Institut, Department of Chemistry, Technische Universität Darmstadt, Alarich-Weiss-Str. 12, 64287, Darmstadt (Germany); Krell, Lisa; Schnagl, Johann [BMW Group, Hufelandstraße 4, 80788 Munich (Germany); Stark, Robert W. [Physics of Surfaces, Institute of Materials Science, Technische Universität Darmstadt, Alarich-Weiss-Str. 16, 64287 Darmstadt (Germany); Center of Smart Interfaces, Technische Universität Darmstadt, Alarich-Weiss-Str. 10, 64287 Darmstadt (Germany); and others

2016-05-15

Highlights: • The water CA of O{sub 2} and H{sub 2} plasma treated a-C:H and ta-C changes from hydrophillic to hydrophobic on aging. • XPS study indicates that the decrease in surface energy of plasma treated a-C:H and ta-C could be due to adsorption of organic component from air. • The COFLFM of O{sub 2} and H{sub 2} plasma treated a-C:H and ta-C decreased upon aging. • The COF of glycerol lubricated ta-C showed no sign of change upon aging. - Abstract: Surface modification with gas plasma is an efficient and easy way to improve the surface energy and the tribological behavior of diamond-like carbon (DLC) coatings, e.g., in biomedical implants or as protective coatings. However, the long-term performance of the plasma treated DLC coatings is not fully clear. We thus studied the long-term stability of two kinds of DLC coatings, namely (a) hydrogenated amorphous carbon (a-C:H) and (b) tetrahedral amorphous carbon (ta-C) treated at different radio frequency (RF) power and time of oxygen (O{sub 2}) and hydrogen (H{sub 2}) plasma. Their surface properties, e.g. surface wettability, structure and tribological behavior, were studied at regular intervals for a period of two months using contact angle goniometer, Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), lateral force microscopy (LFM) and ball on disc apparatus. The surface energy of both the coatings decreased upon aging. The higher the RF power and time of treatment, the higher was the hydrophobicity upon aging. XPS analysis showed that the increase in hydrophobicity could be due to adsorption of unavoidable volatile organic components in the atmosphere. The H{sub 2} plasma treated ta-C was capable of rearranging its structural bonds upon aging. The nano-friction measurements by LFM showed that the coefficient of friction of plasma treated a-C:H and ta-C decreased upon aging. The results indicate that the surface properties of plasma treated a‐C:H and ta‐C are not stable on long-term and are

ANALISIS DAYA SAING KEDELAI INDONESIA

Directory of Open Access Journals (Sweden)

Sarwono Sarwono

2014-09-01

Full Text Available RCA (Revealed Comparative Advantage index of soybean in Indonesia from 1983 up to 2013 is less than one, mostly. It means that the competitiveness of soybean in Indonesia is low. The purpose of this study is to analyze the factors influence the soybean competitiveness. OLS (Ordinary Least Square was used as the analysis method. Hypotheses test based on that analysis model is not bias, so that, classic divergence test is needed. It is for getting the Best Linier Unbiased Estimator (BLUE appraisal. T statistic and F statistic were also applied. The result of this research shows that production and export have positive and significant influence. In addition, exchange rate and government policy do not influence the Indonesia soybean competitiveness.Indeks RCA (Revealed Comparative Advantage kedelai Indonesia dari tahun 1983-2013 kecenderungan bernilai kurang dari satu yang berarti daya saing kedelai Indonesia rendah.Penelitian ini bertujuan untuk menganalisis faktor-faktor yang mempengaruhi daya saing kedelai Indonesia.Metode analisis yang digunakan adalah Ordinary Least Square (OLS.Pengujian hipotesis berdasarkan model analisis tersebut tidak bias maka perlu dilakukan uji penyimpangan klasik yang tujuannya agar diperoleh penaksiran yang bersifat Best Linier Unbiased Estimator (BLUE.Pengujian statistik menggunakan uji t statistikdan uji f statistik.Hasil penelitian ini menunjukkan bahwa produksi dan ekspor berpengaruh secara positif dan signifikan terhadap daya saing kedelai Indonesia. Nilai tukar rupiah dan kebijakan pemerintah tidak berpengaruh terhadap daya saing kedelai Indonesia.

Activation of functional α7-containing nAChRs in hippocampal CA1 pyramidal neurons by physiological levels of choline in the presence of PNU-120596.

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Bopanna I Kalappa

2010-11-01

Full Text Available The level of expression of functional α7-containing nicotinic acetylcholine receptors (nAChRs in hippocampal CA1 pyramidal neurons is believed to be very low compared to hippocampal CA1 interneurons, and for many years this expression was largely overlooked. However, high densities of expression of functional α7-containing nAChRs in CA1 pyramidal neurons may not be necessary for triggering important cellular and network functions, especially if activation of α7-containing nAChRs occurs in the presence of positive allosteric modulators such as PNU-120596.An approach previously developed for α7-containing nAChRs expressed in tuberomammillary neurons was applied to investigate functional CA1 pyramidal α7-containing nAChRs using rat coronal hippocampal slices and patch-clamp electrophysiology. The majority (∼71% of tested CA1 pyramidal neurons expressed low densities of functional α7-containing nAChRs as evidenced by small whole-cell responses to choline, a selective endogenous agonist of α7 nAChRs. These responses were potentiated by PNU-120596, a novel positive allosteric modulator of α7 nAChRs. The density of functional α7-containing nAChRs expressed in CA1 pyramidal neurons (and thus, the normalized net effect of activation, i.e., response net charge per unit of membrane capacitance per unit of time was estimated to be ∼5% of the density observed in CA1 interneurons. The results of this study demonstrate that despite low levels of expression of functional pyramidal α7-containing nAChRs, physiological levels of choline (∼10 µM are sufficient to activate these receptors and transiently depolarize and even excite CA1 pyramidal neurons in the presence of PNU-120596. The observed effects are possible because in the presence of 10 µM choline and 1-5 µM PNU-120596, a single opening of an individual pyramidal α7-containing nAChR ion channel appears to transiently depolarize (∼4 mV the entire pyramidal neuron and occasionally

Performance of Buildings in the 2009 Western Sumatra Earthquake

Science.gov (United States)

Deierlein, G.; Hart, T.; Alexander, N.; Hausler, E.; Henderson, S.; Wood, K.; Cedillos, V.; Wijanto, S.; Cabrera, C.; Rudianto, S.

2009-12-01

The M7.6 earthquake of 30 September 2009 in Western Sumatra, Indonesia caused significant damage and collapse to hundreds of buildings and the deaths of 1,117 people. In Padang City, with a population of about 900,000 people, building collapse was the primary cause of deaths and serious injuries (313 deaths and 431 serious injuries). The predominant building construction types in Padang are concrete moment frames with brick infill and masonry bearing wall systems. Concrete frames are common in multistory commercial retail buildings, offices, schools, and hotels; and masonry bearing wall systems are primarily used in low-rise (usually single story) residential and school buildings. In general, buildings that collapsed did not conform to modern seismic engineering practices that are required by the current Indonesian building code and would be expected in regions of moderate to high seismicity. While collapse of multi-story concrete buildings was more prevalent in older buildings (more than 10 years old), there were several newer buildings that collapsed. Primary deficiencies identified in collapsed or severely damaged buildings included: (a) soft or weak stories that failed in either by sidesway mechanisms or shear failures followed by loss of axial capacity of columns, (b) lack of ductile reinforcing bar detailing in concrete beams, columns, and beam-column joints, (c) poor quality concrete and mortar materials and workmanship, (d) vulnerable building configurations and designs with incomplete or deficient load paths, and (e) out-of-plane wall failures in unreinforced (or marginally reinforced) masonry. While these deficiencies may be expected in older buildings, damage and collapse to some modern (or recently rennovated buildings) indicates a lack of enforcement of building code provisions for design and construction quality assurance. Many new buildings whose structural systems were undamaged were closed due to extensive earthquake damage to brick infill walls

Identification of domestic needs of modular HTR for electric and heat process industry in Indonesia

International Nuclear Information System (INIS)

Rusli, A.; Arbie, B.

2000-01-01

Identification of potential applications of the modular high temperature gas-cooled reactor (HTGR) in Indonesia has been carried out his was done by surveying and analysing the electric and industrial heat process which included captive power for household and industrial complexes in 13 regional operation areas covered by PT PLN National Electric Company. The area includes from the western Aceh to the eastern Irian Jaya, cities which are 6000 miles apart. Surveying was conducted for several parameters that electric and process heat demand in each region including captive power, geological characteristics of the region, distance of each region from conventional energy resources and the existence of petrochemical industries or other industries which use high temperatures (>500 deg C). In order to obtain a scale of priority in each region, credit points (1-3) and sensitivity factors (0-1) were applied to obtain the total significant value. The regions included are: the east cost of Sumatra, the north coast of Java, the west, south and east coat of Kalimantan as well as the south coast of Sulawesi, beyond which there are thousands of small islands that are safe from a geological and a tectonic point of view. In the preliminary survey, the analysation showed that Regions III, IV, XII and XIII have a high potential priority, followed by Regions I, II, VI, VIII and IX. The potential of domestic participation in the first and second unit was also investigated in relation to the possibility of implementing the HTGR project in Indonesia in the future, and it amounted to about 26% and 31% of the total cost for the first and second units, respectively. A summary of results is shown in Table 1. (authors)

Vagus nerve stimulation mediates protection from kidney ischemia-reperfusion injury through α7nAChR+ splenocytes.

Science.gov (United States)

Inoue, Tsuyoshi; Abe, Chikara; Sung, Sun-Sang J; Moscalu, Stefan; Jankowski, Jakub; Huang, Liping; Ye, Hong; Rosin, Diane L; Guyenet, Patrice G; Okusa, Mark D

2016-05-02

The nervous and immune systems interact in complex ways to maintain homeostasis and respond to stress or injury, and rapid nerve conduction can provide instantaneous input for modulating inflammation. The inflammatory reflex referred to as the cholinergic antiinflammatory pathway regulates innate and adaptive immunity, and modulation of this reflex by vagus nerve stimulation (VNS) is effective in various inflammatory disease models, such as rheumatoid arthritis and inflammatory bowel disease. Effectiveness of VNS in these models necessitates the integration of neural signals and α7 nicotinic acetylcholine receptors (α7nAChRs) on splenic macrophages. Here, we sought to determine whether electrical stimulation of the vagus nerve attenuates kidney ischemia-reperfusion injury (IRI), which promotes the release of proinflammatory molecules. Stimulation of vagal afferents or efferents in mice 24 hours before IRI markedly attenuated acute kidney injury (AKI) and decreased plasma TNF. Furthermore, this protection was abolished in animals in which splenectomy was performed 7 days before VNS and IRI. In mice lacking α7nAChR, prior VNS did not prevent IRI. Conversely, adoptive transfer of VNS-conditioned α7nAChR splenocytes conferred protection to recipient mice subjected to IRI. Together, these results demonstrate that VNS-mediated attenuation of AKI and systemic inflammation depends on α7nAChR-positive splenocytes.

Introduction of an Electronic Forum for Annual Development Planning (A Case Study in Banyuasin Regency, South Sumatra, Indonesia

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Irwanto Irwanto

2014-01-01

Full Text Available Indonesian constitution was amended in 1999 and requested for local government to establish bottom up planning process that has been set as a standard approach to accommodate local aspiration in the making of annual development plan. The Musrenbang (Musyawarah Perencanaan Pembangunan/The Deliberation of development Plan was amended by Law No. 25/2004 as the stages of planning formulation process in which stakeholders and Public Administrator sit down for forum to communicate each other to find best means for local problem solution. Musrenbang need to modify since it tend to not work as become effective mechanism to accommodate aspirations of stakeholders (bottom level and hand them over to local government (upper level due to several barriers, such as; geographical distance, limited transportation system, irregular political intervention and bureaucratic red tape. Using Information Communication Technology (ICT that able to simplify the planning process by utilizing the people’s interactions expectedly can make simpler and faster procedure, including maximizing the role of Musrenbang. An Electronic forum for annual development planning will set to improve validity, effectiveness and efficiency. Banyuasin Regency, South Sumatera, Indonesia is now making preparation to introduce this system. PCM method was applied to analyze the problems for its introduction. Keywords: development plan, information communication technology, local government, musrenbang.

Fiscal 1997 for the upgrading of the Asia/Pacific coal development. Survey of the optimization of the coal transportation system in Indonesia; 1997 nendo Asia Taiheiyo sekitan kaihatsu kodoka chosa. Indonesia ni okeru sekitan yuso system saitekika chosa

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-03-01

The paper summarized the results of Phase 1 and Phase 2 surveys conducted based on `Agreement on the comprehensive survey of a coal transportation system in South Sumatra` concluded between NEDO and the Ministry of Mine and Energy in Indonesia. In addition to the data collection and site surveys made in Phase 1, conducted in Phase 2 were determination of sites for harbors, determination of a scenario on coal transportation from coal mines to harbors, optimization of the coal transportation system, social/economic assessment, and proposal on the optimum transportation system. The results of the simulation were as follows: It is the most advantageous to transport coal from coal deposit area to harbor by rail and from harbor to Paiton by barge weighed over 10,000 tons. Tanjung Api Api is the most advantageous as harbor. The production scale which is profitable became more than 15 million tons. The present coal price of PTBA is $25/t arriving Suralaya. The coal in this case is said to be 5500kcal/kg in quality, and the coal of the same quality to this is only profitable. 8 refs., 68 figs., 104 tabs.

The Structure and Function of Male Thomas Langur Loud Calls

NARCIS (Netherlands)

Wich, Serge Alexander

2002-01-01

This study has addressed the acoustical structure of male loud calls and their function in Thomas langur social organisation. Thomas langurs are medium sized primate that lives in Sumatra, Indonesia. Ome of the characteristics of this species is the loud call of males. Several functions for loud

Male Fruit Fly, Bactrocera tau (Diptera; Tephritidae) attractants from Elsholtzia pubescens Bth

NARCIS (Netherlands)

Hasyim, A.; Muryati,; Mizu Istianto,; Kogel, de W.J.

2007-01-01

Studies on the ability of different plant extracts to attract male fruit flies indicated that an extract of Elsholtzia pubescens attracted male Bactrocera tau fruit flies in Passion fruit orchards in West Sumatra, Indonesia. Analyses of the plant extract showed that the major compound present was

Determinan Ekspor CPO Indonesia

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Ratih Rosita

2014-06-01

Full Text Available Palm oil is one of the products that are important to the economy of Indonesia. This study aims to analyze the performance of Indonesia's CPO exports and to look for the influence of the independent variables such as production volume CPO, CPO consumption and the value of the rupiah against the U.S. dollar. The authors of this study tested using the Method of Error Correction Model. The time interval used is from 1998 to 2011 with the data quarter. The findings suggest that Indonesia's CPO production volume variables exert a positive and significant impact on the number of Indonesian CPO exports in both the short and long term, then the variable volume Indonesia CPO consumption in the short and long term is also a significant effect on the number of Indonesian CPO exports but negatively related, this is due to the domestic CPO consumption greater that the capacity to export will be reduced. Variables of the Rupiah against the U.S. dollar also affects Indonesia's CPO exports significantly and negatively related to both the short and long term and conditions of the depreciation of the rupiah exchange rate is not enough to effectively be driving exports. Estimates show that the close relationship between external demand caused exports to Indonesia's export performance vulnerable to external shocks. Side factors are also a determinant of export performance.

EFISIENSI PERBANKAN SYARIAH DI INDONESIA

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Afif Amirillah

2014-09-01

Full Text Available This research aims to find out the factors that can cause the efficiency value difference of Islamic Banking in In-donesia. The data at this research is monetary data of Islamic Banking. It was obtained from Bank of Indonesia. Then, it was divided into input and output variables. The determination of input output variables at this research uses Value Added Approach. Its input output variables consist of Demand Deposits, Saving Deposits, Time Depo-sits, Paid -In Capital, Placement at Bank ofIndonesia, Inter Bank Assets, Mudharabah, Musyara kah, Murabahah, Istishna, Ijarahand Qardh. This research used Data Envelopment Analysis method. This method has a strength that is having the capability to measure inefficiency input output variables, so that, the variable can have the efficiency. This research has resulted Islamic Banking efficiency in Indonesia, but it does not include BPRS. The mean efficiency of Islamic banking in Indonesia is 99,94%. Penelitian ini bertujuan mencari faktor –faktor penyebab perbedaan nilai efisiensiperbankan syariah di Indo-nesia yang dibandingkan secara relatif untuk setiap periode. Data yang digunakan pada penelitian ini menggu-nakan data keuangan perbankan syariah yang diperoleh dari Bank Indonesia kemudian dibagi menjadi variabel input dan output. Penentuan variabel input dan output pada penelitian ini menggunakan pendekatan Value Added Approach. Variabel input outputnyaterdiri dari : Giro iB, Tabungan iB, Deposito iB, Modal disetor, Pen-empatan padaBank Indonesia, Penempatan pada bank lain, Mudharabah, Musyarakah, Murabahah,Istishna, Ijarah dan Qardh. Pada penelitian ini menggunakan metode Data Envelopment Analysis yang mempunyai kel-ebihan dalam menghitung efisiensi untuk setiap variabel input outputyang mengalami inefisiensi. Penelitian ini menghasilkan nilai efisiensi perbankan syariah di Indoenesia (tidak termasuk BPRS. Efisiensi perbankan syariah di Indonesia mengalami efisiensi rata-rata sebesar 99,94%.

EPA Collaboration with Indonesia

Science.gov (United States)

Indonesia is a key actor in the global environmental arena. In addition to significant ecological resources, Indonesia also has the fourth largest population in the world and the third largest greenhouse gas emissions.

Attenuated nicotine‐like effects of varenicline but not other nicotinic ACh receptor agonists in monkeys receiving nicotine daily

Science.gov (United States)

Cunningham, Colin S; Moerke, Megan J; Javors, Martin A; Carroll, F Ivy

2016-01-01

Background and Purpose Chronic treatment can differentially impact the effects of pharmacologically related drugs that differ in receptor selectivity and efficacy. Experimental Approach The impact of daily nicotine treatment on the effects of nicotinic ACh receptor (nAChR) agonists was examined in two groups of rhesus monkeys discriminating nicotine (1.78 mg·kg−1 base weight) from saline. One group received additional nicotine treatment post‐session (1.78 mg·kg−1 administered five times daily, each dose 2 h apart; i.e. Daily group), and the second group did not (Intermittent group). Key Results Daily repeated nicotine treatment produced a time‐related increase in saliva cotinine. There was no significant difference in the ED50 values of the nicotine discriminative stimulus between the Daily and Intermittent group. Mecamylamine antagonized the effects of nicotine, whereas dihydro‐β‐erythroidine did not. Midazolam produced 0% nicotine‐lever responding. The nAChR agonists epibatidine, RTI‐36, cytisine and varenicline produced >96% nicotine‐lever responding in the Intermittent group. The respective maximum effects in the Daily group were 100, 72, 59 and 28%, which shows that the ability of varenicline to produce nicotine‐like responding was selectively decreased in the Daily as compared with the Intermittent group. When combined with nicotine, both varenicline and cytisine increased the potency of nicotine to produce discriminative stimulus effects. Conclusion and Implications Nicotine treatment has a greater impact on the sensitivity to the effects of varenicline as compared with some other nAChR agonists. Collectively, these results strongly suggest that varenicline differs from nicotine in its selectivity for multiple nAChR subtypes. PMID:27667659

nAChR dysfunction as a common substrate for schizophrenia and comorbid nicotine addiction: current trends and perspectives

Science.gov (United States)

Parikh, Vinay; Kutlu, Munir Gunes; Gould, Thomas J.

2016-01-01

Introduction The prevalence of tobacco use in the population with schizophrenia is enormously high. Moreover, nicotine dependence is found to be associated with symptom severity and poor outcome in patients with schizophrenia. The neurobiological mechanisms that explain schizophrenia-nicotine dependence comorbidity are not known. This study systematically reviews the evidence highlighting the contribution of nicotinic acetylcholine receptors (nAChRs) to nicotine abuse in schizophrenia. Methods Electronic data bases (Medline, Google Scholar, and Web of Science) were searched using the selected key words that match the aims set forth for this review. A total of 275 articles were used for the qualitative synthesis of this review. Results Substantial evidence from preclinical and clinical studies indicated that dysregulation of α7 and β2-subunit containing nAChRs account for the cognitive and affective symptoms of schizophrenia and nicotine use may represent a strategy to remediate these symptoms. Additionally, recent meta-analyses proposed that early tobacco use may itself increase the risk of developing schizophrenia. Genetic studies demonstrating that nAChR dysfunction that may act as a shared vulnerability factor for comorbid tobacco dependence and schizophrenia were found to support this view. The development of nAChR modulators was considered an effective therapeutic strategy to ameliorate psychiatric symptoms and to promote smoking cessation in schizophrenia patients. Conclusions The relationship between schizophrenia and smoking is complex. While the debate for the self-medication versus addiction vulnerability hypothesis continues, it is widely accepted that a dysfunction in the central nAChRs represent a common substrate for various symptoms of schizophrenia and comorbid nicotine dependence. PMID:26803692

Effects of acetylcholine (ACh) and norepinephrine (NE) on phosphatidylinositol 4,5-bisphosphate (PIP2) turnover in rabbit cornea

International Nuclear Information System (INIS)

Akhtar, R.A.; Abdel-Latif, A.A.

1986-01-01

Muscarinic cholinergic and α 1 -adrenergic agonists provoke hydrolysis of PIP 2 into diacylglycerol (DG) and inositol trisphosphate (IP 3 ) in a wide variety of tissue. Recently, IP 3 has been shown to mobilize Ca 2+ from ER in several permeabilized tissue preparations. Although rabbit cornea is enriched in ACh and NE, the physiological function of these neurotransmitters is unclear. The present studies were initiated to determine the effects of cholinergic and adrenergic agonists on PIP 2 turnover in the cornea. Addition of ACh or NE (50 μM each) to the 32 P-labeled corneas for 10 min decreased the radioactivity in PIP 2 by 33 and 36%, and increased the radioactivity in phosphatidic acid by 72 and 52%, respectively. When the corneas were labeled with myo-[ 3 H]inositol, ACh and NE increased the accumulation of IP 3 by 92 and 48%, respectively. The effects of ACh and NE on phospholipid labeling and IP 3 accumulation were specifically inhibited by atropine (10 μM) and prazosin (10 μM), respectively. The data suggest the presence of muscarinic cholinergic and α 1 -adrenergic receptors in the rabbit cornea. Furthermore, activation of these receptors leads to cleavage of PIP 2 into DG and IP 3 which may function as second messengers in this tissue

Gynecological cancer in Indonesia.

Science.gov (United States)

Aziz, M Farid

2009-03-01

To overview the status of gynecologic cancer in Indonesia. Information regarding Indonesia obtained from World Bank Report and Statistical Yearbook of Indonesia 2007, epidemiological data obtained from Histopathological Data of Cancer in Indonesia 2002, Department of Health-Registry Body of Indonesian Specialist of Pathology Association-Indonesian Cancer Society; Various Hospitals in big Cities in Indonesia. Indonesia is an Archipelago with a total area of 1,922,570.00 km(2), the population is 222,192,000 (2006), the fourth world rank. Female is 49.86% with life expectancy 69 years. Gross National Product per Capita is 690.00 USD. Histopathological report in 2002 revealed that cervical cancer, ovarian cancer and uterine cancer were the most frequent cancer among female, which were the first (2,532 cases), the third (829 cases) and the eighth (316 cases) rank respectively. The peak age for cervical, uterine and ovarian cancer was 45-54 years. HPV 16, 18 were found in 82% of invasive cervical. Data from various academic hospitals in 2007 showed that cervical cancer is the most common malignancy followed by ovary, uterus, vulva and vagina. Five-year survival rate of stage I, II, III, IV cervical cancer were 50%, 40%, 20%, and 0% respectively. Overall five-year survival rate of carcinoma of the ovary was 54.8%. If sub-classified by stage, five-year survival rate are 94.3%, 75.0%, 31%, and 11.7% for stage I, II, III, and IV respectively. Five-year disease-free survival rate of endometrial cancer was 71.9%. Indonesia is the biggest Archipelago with a dense population but the income per capita still low (poor country). The most common gynecologic cancer is cervical cancer, followed by ovarian and uterine cancer. These cancers are included in top ten cancers in Indonesia. HPV 16, 18 were the most cause of cervical cancer. The five-year survival rates are comparable with world report.

The potential of soil fungi associated with potato rhizosphere to control root knot nematode (Meloidogyne spp.) on potato

Science.gov (United States)

Utari, E.; Lisnawita; Safni, I.; Lubis, K.; Tantawi, AR; Hasanuddin

2018-02-01

The root knot nematode (Meloidogyne spp.) is one of important pathogens on potato crops in North Sumatra, Indonesia. This nematode causes significant crop losses on potatoes directly and indirectly. The effect of fungal isolates (Trichoderma sp. 1, Mucor sp.1, Aspergillus sp. 2, Mucor sp. 2) that were isolated from rhizosphere of potato in North Sumatra were studied in green house experiments on the growth of potato and the reproduction of the nematode (Meloidogyne spp). The results showed that Trichoderma sp. 1 caused a significant gall reduction, while Mucor sp.1 and Mucor sp.2 could improve the growth of potato.

Two New Nepenthes Species from the Philippines and an Emended Description of Nepenthes ramos

OpenAIRE

Gronemeyer, Thomas; Suarez, Wally; Nuytemans, Herman; Calaramo, Michael; Wistuba, Andreas; Mey, Fran?ois S.; Amoroso, Victor B.

2016-01-01

With 50 species of the genus Nepenthes L. currently described from the Philippines, it is without doubt that the country, along with the islands of Sumatra (Indonesia) and Borneo (Indonesia, Malaysia, Brunei), should be considered the center of diversity of the genus. In this work, we describe two new species. One species, N. aenigma sp. nov., is from Ilocos Norte province on Luzon Island and has the—for Nepenthes—unusual ecological preference to grow in dense vegetation in deep shade. The ot...

Pengaruh Bauran Pemasaran (Marketing Mix) Dan Kualitas Pelayanan Terhadap Kepuasan Pelanggan di A&W Restaurants di Sun Plaza Medan

OpenAIRE

Purba, Aurora Tianisari

2012-01-01

A&W Restaurants Sun Plaza Medan is one of the company engaged in the fast food (fast food), which the company must implement appropriate marketing strategies to achieve corporate objectives and service are also very necessary to provide and create customer satisfaction at the A&W Restaurants well across Indonesia especially in Medan, North Sumatra. Competition experienced by the fast food company A&W Restaurants in Indonesia is quite tight, given the many fast food company such as Kentucky Fr...

Pemberitaan Media Pers Indonesia

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Ashadi Siregar

2006-03-01

Full Text Available New freedom and democratic atmosphere existing in Indonesia allow the Indonesian press enjoys its new significant position. This can expand the Indonesian press goals, particularly in enriching the industrial aspiration of the institution. However, bearing in mind that Indonesia is a multicultural country, the Indonesian press can also strengthen the various demographic backgrounds of the state leading to the unity of Indonesia. This article discusses four points of the Indonesian press that need to he considered by the mass media professionals.

Quelques espèces nouvelles d’hispides de Sumatra appartenant au Musée de Leyde

NARCIS (Netherlands)

Gestro, R.

1897-01-01

Sur le point d’entreprendre l’étude des Hispides recueillies à Sumatra par M. le Doct. E. Modigliani, j’ai demandé à M. Ritsema, le savant conservateur de la collection d’insectes du Musée de Leyde, la communication de quelques espèces dans le but de faciliter mon travail. Mon aimable collègue a

Genesis of Pb-Zn-Cu-Ag Deposits within Permian Carboniferous-Carbonate Rocks in Madina Regency, North Sumatra

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Bhakti Hamonangan Harahap

2015-09-01

Full Text Available DOI:10.17014/ijog.2.3.167-184Strong mineralized carbonate rock-bearing Pb-Zn-Cu-Ag-(Au ores are well exposed on the Latong River area, Madina Regency, North Sumatra Province. The ore deposit is hosted within the carbonate rocks of the Permian to Carboniferous Tapanuli Group. It is mainly accumulated in hollows replacing limestone in the forms of lensoidal, colloform, veins, veinlets, cavity filling, breccia, and dissemination. The ores dominantly consist of galena (126 000 ppm Pb and sphalerite (2347 ppm Zn. The other minerals are silver, azurite, covellite, pyrite, marcasite, and chalcopyrite. This deposit was formed by at least three phases of mineralization, i.e. pyrite and then galena replaced pyrite, sphalerite replaced galena, and pyrite. The last phase is the deposition of chalcopyrite that replaced sphalerite. The Latong sulfide ore deposits posses Pb isotope ratio of 206Pb/204Pb = 19.16 - 20.72, 207Pb/204Pb = 16.16 - 17.29, and 208Pb/204Pb = 42.92 - 40.78. The characteristic feature of the deposit indicates that it is formed by a sedimentary process rather than an igneous activity in origin. This leads to an interpretation that the Latong deposit belongs to the Sedimentary Hosted Massive Sulfide (SHMS of Mississippi Valley-Type (MVT. The presence of SHMS in the island arc such as Sumatra has become controversial. For a long time, ore deposits in the Indonesian Island Arc are always identical with the porphyry and hydrothermal processes related to arc magmatism. This paper is dealing with the geology of Latong and its base metal deposits. This work is also to interpret their genesis as well as general relationship to the regional geology and tectonic setting of Sumatra.

Determinan Ekspor CPO Indonesia

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Ratih Rosita

2014-06-01

Full Text Available Palm oil is one of the products that are important to the economy of Indonesia. This study aims to analyze the performance of Indonesia's CPO exports and to look for the influence of the independent variables such as production volume CPO, CPO consumption and the value of the rupiah against the U.S. dollar. The authors of this study tested using the Method of Error Correction Model. The time interval used is from 1998 to 2011 with the data quarter. The findings suggest that Indonesia's CPO production volume variables exert a positive and significant impact on the number of Indonesian CPO exports in both the short and long term, then the variable volume Indonesia CPO consumption in the short and long term is also a significant effect on the number of Indonesian CPO exports but negatively related, this is due to the domestic CPO consumption greater that the capacity to export will be reduced. Variables of the Rupiah against the U.S. dollar also affects Indonesia's CPO exports significantly and negatively related to both the short and long term and conditions of the depreciation of the rupiah exchange rate is not enough to effectively be driving exports. Estimates show that the close relationship between external demand caused exports to Indonesia's export performance vulnerable to external shocks. Side factors are also a determinant of export performance. Keywords: palm oil, CPO consumption, Error Correction Model

AN ANALYSIS OF MANUFACTURING MARKET STRUCTURE IN NORTH SUMATRA PROVINCE

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Muhammad Asaad

2013-04-01

Full Text Available This study aims to analyze market structure and manufacturing industry performance on the economy of North Sumatra. The analysis uses two approaches, namely SCP analysis and econometric model. The data used is the Survey of Large Medium 2005-2009. The result shows that the structure of the industry is more dominant, including tight oligopoly, only small parts which belong to loose oligopoly and oligopoly markets. Some industries which have important roles for the economy are the palm oil industry, food and beverage industry, rubber industry and rubber products, and iron and steel basic industries, and basic non-ferrous metals.Keywords: market structure, industry performance, manufacturing industry, local economyJEL classification numbers: L10, L20, L60

Combined Arms Warfare in the 21st Century: Maximizing the Capability of U.S. Army Future Combat System Equipped Brigade Combat Teams to Conduct Combined Arms Operations

Science.gov (United States)

2008-06-13

defenses, and surf ; a landing from the air but free of the 65 inflexibility, tactical disorder, and disorganization of parachute operations; an...taken place since the Cold War include Aceh province on the island of Sumatra in the country of Indonesia and the Darfur region of western Sudan

MYCOTOXIN CONTAMINATION ON CORN USED BY FEED MILLS IN INDONESIA

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Budi Tangendjaja

2016-10-01

Full Text Available Mycotoxins which are secondary metabolites of fungi contaminate agricultural products such as corn and have deleterious effects on human and animal. The objective of this study was to evaluate the mycotoxin contamination on local and imported corn samples collected from different feed mills in Indonesia. Three hundred fifty six of corn samples (0.50 kg each were sent by several feed mills to the Indonesian Research Institute for Animal Production during 2005-2006. The background information accompanied with each sample was country/province of origins, harvesting seasons, postharvest drying methods, moisture levels, grades, and varieties. The samples were analyzed for various mycotoxins, i.e aflatoxin (AFL, ochratoxin (OCRA, zearalenone (ZEN, fumonisin (FUM, deoxynivalenol (DON, and T2 toxin using commercial kits, except for AFL which was analysed using a kit developed by the Indonesian Research Center for Veterinary Science. The results showed that average AFL level in the contaminated corn originated from Indonesia was 59 µg kg-1, almost 7 times higher than that imported from the USA or Argentina. Among the types of mycotoxins detected, FUM was the highest with an average of 1193 µg kg-1, followed by DON, ZEN and OCRA at level of 324, 22 and 2 µg kg-1, respectively. Mycotoxin levels in the contaminated local corn samples varied depending on the province of origins as well as harvesting seasons, postharvest drying methods, and moisture contents. The least mycotoxin contaminations were found on corn originated from NorthSumatra and Lampung with the AFL levels were < 20 and < 50 µg kg-1, respectively, lower than those from East Java, Central Java and South Sulawesi (64-87 µg kg-1. Mycotoxin levels, however, were less affected by grading made by feed mills and corn varieties. It is indicated that AFL was the most important mycotoxin as far as for animal feeding concerned, as it contaminated almost 50% of local corn with the level of

Characterization of biomass burning aerosols from forest fire in Indonesia

Science.gov (United States)

Fujii, Y.; Iriana, W.; Okumura, M.; Lestari, P.; Tohno, S.; Akira, M.; Okuda, T.

2012-12-01

Biomass burning (forest fire, wild fire) is a major source of pollutants, generating an estimate of 104 Tg per year of aerosol particles worldwide. These particles have adverse human health effects and can affect the radiation budget and climate directly and indirectly. Eighty percent of biomass burning aerosols are generated in the tropics and about thirty percent of them originate in the tropical regions of Asia (Andreae, 1991). Several recent studies have reported on the organic compositions of biomass burning aerosols in the tropical regions of South America and Africa, however, there is little data about forest fire aerosols in the tropical regions of Asia. It is important to characterize biomass burning aerosols in the tropical regions of Asia because the aerosol properties vary between fires depending on type and moisture of wood, combustion phase, wind conditions, and several other variables (Reid et al., 2005). We have characterized PM2.5 fractions of biomass burning aerosols emitted from forest fire in Indonesia. During the dry season in 2012, PM2.5 aerosols from several forest fires occurring in Riau, Sumatra, Indonesia were collected on quartz and teflon filters with two mini-volume samplers. Background aerosols in forest were sampled during transition period of rainy season to dry season (baseline period). Samples were analyzed with several analytical instruments. The carbonaceous content (organic and elemental carbon, OC and EC) of the aerosols was analyzed by a thermal optical reflectance technique using IMPROVE protocol. The metal, inorganic ion and organic components of the aerosols were analyzed by X-ray Fluorescence (XRF), ion chromatography and gas chromatography-mass spectrometry, respectively. There was a great difference of chemical composition between forest fire and non-forest fire samples. Smoke aerosols for forest fires events were composed of ~ 45 % OC and ~ 2.5 % EC. On the other hand, background aerosols for baseline periods were

ANALISIS EKSPOR KOPI INDONESIA

Directory of Open Access Journals (Sweden)

SRI - WIDAYANTI

2012-05-01

Full Text Available ABSTRACT   This study aimed at analyzing, firstly, the factors influencing the coffee export of Indonesia; secondly, the factors influencing the domestic coffee supply; and thirdly, the factors influencing the domestic coffee demand. This research used secondary data, time series data of 1975–1997 which were collected from many resources, i.e. Statistical Center Bureau (BPS, Trade Department, Indonesian Coffee Exporter Association, Forestry and Commercial Agricultural Enterprise Department, and the Indonesian Bank. The factors influencing the coffee export of Indonesia as well as the domestic coffee demand and supply were analyzed by simultaneous equation model in the form of double logarithm using the two stage least square method (2SLS. The research results show that the factors influencing the export quantity of coffee were the coffee FOB price, the coffee price in domestic markets, the exchange rate and the coffee supply of the previous year. The coffee export price had negative correlation with the coffee export quantity of Indonesia with export supply elasticity toward the export price of 2.04. In other words, the increase of coffee export price was followed by the decrease of coffee export quantity. This condition was due to the low quality of the coffee export of Indonesia. The coffee price at domestic markets has positive correlation with the coffee export quantity of Indonesia. Export was still conducted when the coffee price at domestic markets increased because the demand for domestic coffee was still very low. Other factors positively influencing the coffee export quantity were the exchange rate of rupiah and the coffee supply of the previous year. The factors influencing the domestic coffee supply were the domestic coffee price, technology level and the coffee supply of the previous year. The domestic coffee price positively related to the coffee supply at domestic markets with a supply elasticity of 0.04. This means that the

Potential Sedimentary Evidence of Two Closely Spaced Tsunamis on the West Coast of Aceh, Indonesia

Science.gov (United States)

Monecke, Katrin; Meilianda, Ella; Rushdy, Ibnu; Moena, Abudzar; Yolanda, Irvan P.

2016-04-01

Recent research in the coastal regions of Aceh, Indonesia, an area that was largely affected by the 2004 Sumatra Andaman earthquake and ensuing Indian Ocean tsunami, suggests the possibility that two closely spaced tsunamis occurred at the turn of the 14th to 15th century (Meltzner et al., 2010; Sieh et al., 2015). Here, we present evidence of two buried sand layers in the coastal marshes of West Aceh, possibly representing these penultimate predecessors of the 2004 tsunami. We discovered the sand layers in an until recently inaccessible area of a previously studied beach ridge plain about 15 km North of Meulaboh, West Aceh. Here, the 2004 tsunami left a continuous, typically a few cm thick sand sheet in the coastal hinterland in low-lying swales that accumulate organic-rich deposits and separate the sandy beach ridges. In keeping with the long-term progradation of the coastline, older deposits have to be sought after further inland. Using a hand auger, the buried sand layers were discovered in 3 cores in a flooded and highly vegetated swale in about 1 km distance to the shoreline. The pair of sand layers occurs in 70-100 cm depth and overlies 40-60 cm of dark-brown peat that rests on the basal sand of the beach ridge plain. The lower sand layer is only 1-6 cm thick, whereas the upper layer is consistently thicker, measuring 11-17 cm, with 8-14 cm of peat in between sand sheets. Both layers consist of massive, grey, medium sand and include plant fragments. They show very sharp upper and lower boundaries clearly distinguishing them from the surrounding peat and indicating an abrupt depositional event. A previously developed age model for sediments of this beach ridge plain suggest that this pair of layers could indeed correlate to a nearby buried sand sheet interpreted as tsunamigenic and deposited soon after 1290-1400AD (Monecke et al., 2008). The superb preservation at this new site allows the clear distinction of two depositional events, which, based on a first

Does Your Patient’s Urine Turns Dark? Alkaptonuria and Low Back Ache: A Literature Review

Science.gov (United States)

Kanniyan, Kalaivanan; Pathak, Aditya C; Dhammi, Ish Kumar; Jain, Anil Kumar

2014-01-01

Introduction: Alkaptonuria is a very rare inborn error of amino acid metabolism due to deficient homogentisic acid (HGA) oxidase enzyme leading to accumulation of HGA in plasma, cartilage, other tissues of human body and its excretion in urine. It has both systemic and peripheral signs and symptoms. Though low back is a common symptom of alkaptonuria but, in the absence of ochronosis it is rare. Alkaptonuria itself is very rare occurrence with no specific treatment option available to reverse the effect as yet. Case Report: A 38-year-old male, embroidery worker presented with chronic low back ache with history of staining of clothes in infancy. Later on laboratory and the radiological investigation patient was diagnosed to have alkaptonuria without ochronosis. No other systemic manifestation was present. Patient was treated conservatively and responded well. Conclusion: Though alkaptonuria is a very rare disease, and the occurrence of low back-ache in absence of ochronosis is much rarer. One must be aware of this inborn error of metabolism. Early diagnosis though being “diagnosis of exclusion” for low back-ache, high index of suspicion is advantageous as symptomatic treatment of the alkaptonuria can be initiated and evaluation of other systemic organs can be done in early stages itself. PMID:27298997

Changes in vegetation and climate as reflected in tooth enamel isotopes of Quaternary mammalian faunas from Indonesia

Science.gov (United States)

Janssen, Renee; Joordens, Josephine; Koutamanis, Dafne; Puspaningrum, Mika; de Vos, John; den Ouden, Natasja; van der Lubbe, Jeroen; Reijmer, John; Hampe, Oliver; Davies, Gareth; Vonhof, Hubert

2017-04-01

Climate and sea level fluctuations play a dominant role in the Quaternary biodiversity dynamics of Indonesia, with glacial-interglacial cycles affecting hydroclimate, vegetation, and animal migrations. We analyzed the carbon (δ13C), oxygen (δ18O), and strontium (87Sr/86Sr) isotopes of bovid, cervid, and suid teeth from several Pleistocene and Holocene sites on Java and Sumatra, in order to refine reconstructions of the paleohabitats of these faunas, gain more insight into their climatic background, and constrain their chronology. Our carbon isotope data indicate that individual sites are strongly dominated by the presence of either C3-browsers or C4-grazers. Herbivores from the Padang Highlands (Sumatra) and Hoekgrot (Java) cave faunas were mainly C3-browsers, while the studied herbivores from Homo erectus-bearing sites Trinil and Sangiran (Java) utilized an almost exclusive C4 diet. The C4 signal of Trinil herbivores confirms that the Hauptknochenschicht (Trinil HK) was deposited during glacial conditions, allowing us to hypothesize that it can be dated to MIS 16, 14 or 12. We propose that the dominant vegetation signals in Indonesian fossil sites, as revealed by δ13C data, reflect a glacial-interglacial contrast. The scarcity of δ13C values typically indicating mixed C3/C4 feeding may indicate that the transition between glacial and interglacial precipitation regimes was relatively abrupt. The observed positive correlation between δ13C and δ18O values can be attributed to the glacial-interglacial contrast between precipitation δ18O values, caused by differences in monsoon intensity. The 87Sr/86Sr data show that the dominant C4 signal observed in the Sangiran and Trinil herbivore faunas corresponds with roaming in a variety of landscape settings, corroborating our hypothesis that the δ13C values are representative of the overall C3/C4vegetation balance in these areas. These results provide a framework that will allow interpretation of future isotope data

Marked point process for modelling seismic activity (case study in Sumatra and Java)

Science.gov (United States)

Pratiwi, Hasih; Sulistya Rini, Lia; Wayan Mangku, I.

2018-05-01

Earthquake is a natural phenomenon that is random, irregular in space and time. Until now the forecast of earthquake occurrence at a location is still difficult to be estimated so that the development of earthquake forecast methodology is still carried out both from seismology aspect and stochastic aspect. To explain the random nature phenomena, both in space and time, a point process approach can be used. There are two types of point processes: temporal point process and spatial point process. The temporal point process relates to events observed over time as a sequence of time, whereas the spatial point process describes the location of objects in two or three dimensional spaces. The points on the point process can be labelled with additional information called marks. A marked point process can be considered as a pair (x, m) where x is the point of location and m is the mark attached to the point of that location. This study aims to model marked point process indexed by time on earthquake data in Sumatra Island and Java Island. This model can be used to analyse seismic activity through its intensity function by considering the history process up to time before t. Based on data obtained from U.S. Geological Survey from 1973 to 2017 with magnitude threshold 5, we obtained maximum likelihood estimate for parameters of the intensity function. The estimation of model parameters shows that the seismic activity in Sumatra Island is greater than Java Island.

Indonesia: An Environmental Security Assessment

Science.gov (United States)

1998-04-01

Planet. New York: The Free Press, 1995. Baker, M. Sharon. “McCaw Raises $1.1 Billion To Wire Asia And Latin America .” Business Journal Serving San...Other illnesses that have been aggravated or caused by the smoke include conjunctivitis, asthma , bronchitis, eczema, and skin and eye ailments. 5...assessment and mitigation project 200,000 UNICEF Provision of 21,650 face masks 20,000 Procurement of ARI drugs for children in Sumatra and Kalimantan

Emergence of Melioidosis in Indonesia.

Science.gov (United States)

Tauran, Patricia M; Sennang, Nurhayana; Rusli, Benny; Wiersinga, W Joost; Dance, David; Arif, Mansyur; Limmathurotsakul, Direk

2015-12-01

Melioidosis is known to be highly endemic in parts of southeast Asia and northern Australia; however, cases are rarely reported in Indonesia. Here we report three cases of melioidosis in Makassar, South Sulawesi, Indonesia occurring between 2013 and 2014. Two patients died and the other was lost to follow-up. Burkholderia pseudomallei isolates from all three cases were identified by the VITEK2 Compact installed in the hospital in 2012. None of the three patients reported received antimicrobials recommended for melioidosis because of the delayed recognition of the organism. We reviewed the literature and found only seven reports of melioidosis in Indonesia. Five were reported before 1960. We suggest that melioidosis is endemic throughout Indonesia but currently under-recognized. Training on how to identify B. pseudomallei accurately and safely in all available microbiological facilities should be provided, and consideration should be given to making melioidosis a notifiable disease in Indonesia. © The American Society of Tropical Medicine and Hygiene.

The Roles of the Supreme Court of the Republic Indonesia in Enforcement of International Arbitral Awards in Indonesia

Directory of Open Access Journals (Sweden)

Mutiara Hikmah

2013-09-01

Full Text Available Indonesia has been being a member of the 1958 New York Convention since 1981, namely upon issuance of the Presidential Decree No. 34 of 1981. Prior to taking into force of the Regulation of the Supreme Court of the Republic of Indonesia No. 1 of 1990 on Procedures for Enforcement of Foreign Arbitral awards, there were still constraints for the foreign business players in term of enforcement of arbitral awards in Indonesia. The Supreme Court as the highest judicial institution in Indonesia holds that international arbitral awards can not be enforced in Indonesia. After the Indonesian Supreme Court has issued such a regulation, enforcement of international arbitral awards in Indonesia began to be enforceable, because the procedural law that governs the procedures for execution of arbitral awards has been clear. In order to regulate better the international arbitral award problems in the hierarchy of legislation, on October 12, 1999, the Law on Arbitration and Alternative Dispute Resolution was promulgated. In that Law, there is a special part discussing the International Arbitration. This study examines the development of international arbitral award enforcement in Indonesia before Indonesia becoming member of the 1958 New York Convention, until nowadays, by analyzing the international arbitral awards that were decided by the Supreme Court of the Republic of Indonesia after the coming into effect of the Arbitration Law.

Perilaku Mahasiswa Fakultas Kedokteran Universitas Sumatera Utara Tentang Konsumsi Makanan Siap Saji (Fast Food) Medan Tahun 2015

OpenAIRE

Rahayu, Try Desfi

2015-01-01

A survey which provided by AC Nielsen (2008) stated that 69% of cities in Indonesia used to consume the fast food. A total of 33% of them saidthat fast food is the choice for their lunch, 25% fortheir dinner, 9% fortheir such snack, and 2% for their breakfast. This condition will be growing along with the increasing consumption of fast food in Indonesia. This research provided by the authors aimed to determine the behavior of students of the Faculty of Medicine, University of North Sumatra (U...

Isolation and identification of indigenous lactic acid bacteria from North Sumatra river buffalo milk

OpenAIRE

Heni Rizqiati; Cece Sumantr; Ronny Rachman Noor; E. Damayanthi; E. I. Rianti

2015-01-01

Buffalo milk is a source of various lactic acid bacteria (LAB) which is potential as culture starter as well as the probiotic. This study was conducted to isolate and identify LAB from indigenous North Sumatra river buffalo milk. Lactic acid bacteria was isolated and grown in medium De Man Rogosa Sharpe Agar (MRSA). The isolation was conducted to obtain pure isolate. The identification of LAB was studied in terms of morphology, physiology, biochemistry and survival on low pH. Morphology test...

Population, environment and sustainable development in Indonesia.

Science.gov (United States)

Jones, G W

1993-12-01

Sustainable development is expressed in terms of living standards and economic welfare. The basic dichotomy of general sustainable development pits the environmentalists who fear that population growth poses grave threats to natural resources against the economic rationalists who envisage that market forces will take care of scarcities and technological development will solve environmental problems. The Brundtland committee defined sustainable development as development that meets the needs of the present without compromising the ability to meet the needs of future generations. An increase in population or per capita income will increase environmental stress, while an increase in efficiency of production will reduce environmental stress. Indonesia is an important case of the interrelationships between population growth and environmental problems. It had 180 million people in 1990. Despite fertility decline the population is expected to increase by 89 million over the next 30 years. The island of Java is subject to the greatest population-related environmental stress because the population numbers 112 million people. Severe erosion already occurred in the 1950s in the uplands, and cultivation is moving further up the slopes of volcanic hillsides to accommodate commercial vegetable growing on previously forested slopes. The underlying problem is population growth and the need for increased crop production and employment. Other causative factors are the building of freeways, airports, and factories; sand and soil extraction; the impact on fisheries of blasting of coral rock; and urbanization. Jakarta has inadequate water supplies and waste disposal and increasing air pollution. In the outer island in South Sulawesi erosion is also severe; in South Sumatra deforestation is widespread as the transmigration program unfolds. Natural resource degradation occurs when population becomes too large in relation to the productivity of the resource base.

HISTORISITAS POLITIK PEREMPUAN INDONESIA

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Wasisto Raharjo Jati

2014-11-01

Full Text Available This article aims to analyze historicity of political participation and representation of women in the political landscape in Indonesia. This paper used the perspective of feminism theory as core analysis in reviewing its issue. Periodicity of Indonesian women's political participation is very volatile and depends on the political situation contemporary. Indonesian women's political participation in the era of colonialism experienced domestication, revivalism in the Sukarno era, stigmatization in the New Order era, and is now experiencing ambiguity in the Reformation era. Indonesian women's political participation need to find a strong platform to promote the aspirations of his peopleKeywords: partisipation, representation, domestification, stigmatization, and women politic.Artikel ini bertujuan untuk menganalisis histo-risitas partisipasi politik dan keterwakilan perempuan dalam lanskap politik di Indonesia. Tu-lisan ini menggunakan perspektif teori feminisme sebagai analisis inti dalam meninjau isu nya. Periodisitas partisipasi politik perempuan Indonesia sangat fluktuatif dan tergantung pada situasi politik kontemporer. Partisipasi politik perempuan Indonesia di era kolonialisme mengalami domestikasi, revivalisme di era Soekarno, stigmatisasi di era Orde Baru, dan sekarang mengalami ambiguitas dalam era Reformasi. Partisipasi politik perempuan Indonesia perlu menemukan platform yang kuat untuk memperjuangkan aspirasi rakyatnyaKata kunci: partisipasi, representasi, domestifikasi, stigmasi, politik perempuan  

Nitrogen fixation of Acacia mangium Willd. from two seed sources ...

African Journals Online (AJOL)

These consisted of bulk seedlots collected from seed orchards in Sumatra, one based on natural provenances from the Cairns region, Queensland, Australia, and the other on the Muting natural provenance, Papua, Indonesia. The seedlots were grown under contrasting P supply (application rates of 0 and 100 kg ha−1) on ...

What a botanist can contribute to conservation in Malesia

NARCIS (Netherlands)

Jacobs, M.

1977-01-01

Reviewing the conservation situation in Indonesia, we see that concern for animals outweighs that for plants. Sumatra with its richer fauna of large mammals, is better cared for than Borneo with its richer flora*. Too often in the reports, a forest is called a forest, to the neglect of the amazing

Inventory of Forts in Indonesia

Science.gov (United States)

Rinandi, N.; Suryaningsih, F.

2015-08-01

The great archipelago in Indonesia with its wealthy and various nature, the products and commodities of tropic agriculture and the rich soil, was through the centuries a region of interest for other countries all over the world. For several reasons some of these countries came to Indonesia to establish their existence and tried to monopolize the trading. These countries such as the Portuguese, the Spanish, the Dutch and the British built strengthened trade stations which later became forts all over Indonesia to defend their interest. The archipelago of Indonesia possesses a great number of fortification-works as legacies of native rulers and those which were built by European trading companies and later became colonial powers in the 16th to the 19th centuries. These legacies include those specific structures built as a defence system during pre and within the period of World War II. These fortresses are nowadaysvaluable subjects, because they might be considered as shared heritage among these countries and Indonesia. It's important to develop a vision to preserve these particular subjects of heritage, because they are an interesting part of the Indonesian history and its cultural treasures. The Government of the Republic of Indonesia has national program to compile a comprehensive documentation of the existing condition of these various types of forts as cultural heritage. The result of the 3 years project was a comprehensive 442 forts database in Indonesia, which will be very valuable to the implementation of legal protection, preservation matters and adaptive re-use in the future.

Inactivation of JAK2/STAT3 Signaling Axis and Downregulation of M1 mAChR Cause Cognitive Impairment in klotho Mutant Mice, a Genetic Model of Aging

Science.gov (United States)

Park, Seok-Joo; Shin, Eun-Joo; Min, Sun Seek; An, Jihua; Li, Zhengyi; Hee Chung, Yoon; Hoon Jeong, Ji; Bach, Jae-Hyung; Nah, Seung-Yeol; Kim, Won-Ki; Jang, Choon-Gon; Kim, Yong-Sun; Nabeshima, Yo-ichi; Nabeshima, Toshitaka; Kim, Hyoung-Chun

2013-01-01

We previously reported cognitive dysfunction in klotho mutant mice. In the present study, we further examined novel mechanisms involved in cognitive impairment in these mice. Significantly decreased janus kinase 2 (JAK2) and signal transducer and activator of transcription3 (STAT3) phosphorylation were observed in the hippocampus of klotho mutant mice. A selective decrease in protein expression and binding density of the M1 muscarinic cholinergic receptor (M1 mAChR) was observed in these mice. Cholinergic parameters (ie, acetylcholine (ACh), choline acetyltransferase (ChAT), and acetylcholinesterase (AChE)) and NMDAR-dependent long-term potentiation (LTP) were significantly impaired in klotho mutant mice. McN-A-343 (McN), an M1 mAChR agonist, significantly attenuated these impairments. AG490 (AG), a JAK2 inhibitor, counteracted the attenuating effects of McN, although AG did not significantly alter the McN-induced effect on AChE. Furthermore, AG significantly inhibited the attenuating effects of McN on decreased NMDAR-dependent LTP, protein kinase C βII, p-ERK, p-CREB, BDNF, and p-JAK2/p-STAT3-expression in klotho mutant mice. In addition, k252a, a BDNF receptor tyrosine kinase B (TrkB) inhibitor, significantly counteracted McN effects on decreased ChAT, ACh, and M1 mAChR and p-JAK2/p-STAT3 expression. McN-induced effects on cognitive impairment in klotho mutant mice were consistently counteracted by either AG or k252a. Our results suggest that inactivation of the JAK2/STAT3 signaling axis and M1 mAChR downregulation play a critical role in cognitive impairment observed in klotho mutant mice. PMID:23389690

Jepara Indonesia Furniture

OpenAIRE

romanzick

2016-01-01

Jepara Indonesia Furniture A wide choice of Indonesian furniture companies provide free business listings to all types of furniture also for outlets and stores. Each section is accessible that contains a comprehensive list of our range of furniture details information and full campaign. We provided a platform create various products along with featured inspiration section related products, services, accessories. Indonesia Furniture Teak Garden Furniture It is bringing customers distinctive as...

Geochemical Investigation of Selected Elements in an Agricultural Soil: Case Study in Sumani Watershed West Sumatera in Indonesia

Directory of Open Access Journals (Sweden)

Aflizar

2016-01-01

Full Text Available This paper presents the geochemical study of agricultural soil and river sediments along Sumani watershed, West Sumatra in Indonesia. We examined the distribution and abundances of 16 elements (Pb, Zn, Cu, Ni, Cr,V, Sr, Rb, Ce, Th, Zr, Si, Ti, Fe Ca, and P in vegetable soil, sawah soil =and river sediment sample, to evaluate the factors controlling their abundances, possible sources, and environmental implications. Average concentrations of Pb, Zn, Cu, Ni, Cr,V, Sr, Rb, Ce, Th, Zr at vegetable (1 soil were 38, 88.3, 38.7, 3, 8, 101, 96, 98, 87, 31 and 218 mg kg-1 , 26, 39.05, 8.8, 13.5, 31, 231.5, 37, 19, 78, 16 and 303.5 mg kg-1 at sawah soil (3, 4 and 30, 61.6, 35.7, 9, 22, 294, 65, 12, 78, 14 and 232 mg kg-1 at river sediment (2, respectively. The concentration of Pb, Rb, Th and Zr at upland vegetables, V and Zr at sawah soil and river sediment were mostly two time Sumatra BCSCST or BCC in several samples. Enrichment factor values showed low to moderate enrichment of Pb, Zn, Cu, Rb, Ce and Zr, whereas Th showed significant contamination at vegetables soil, suggesting contributions from anthropogenic sources. Anthropogenic contributions of most metals mainly originate from natural processes. However, Pb, Ce, Th and Zr ranges of 527–108, 41-89, 66-117 and 35-100%, respectively, at Vegetable and sawah soil and river sediment confirm their anthropogenic contribution. Factor analysis and correlation matrices suggested that elevated metal concentrations at agricultural soil in Sumani watershed might be controlled by pH, CEC, Fe-oxy-hydroxides. Deposition of metals at vegetable and sawah soil and river sediment might be controlled by non-ferrous metal (i.e., aluminosilicates, sediment grain size, or source rock composition (andesite, alluvial fan, undifferentiated volcanic material, granite and gneiss.

Prospek Perekonomian Indonesia dalam Memasuki Afta

OpenAIRE

Basuki, Agus Tri

2002-01-01

This article will analyze Indonesia's economic performance towards ASEAN free trade area (AFTA). From the economic performance, Indonesia is facing high threats, especially on the competitiveness of product and KKN (corruption, collusion, and nepotism) problem that cause high cost economy. So, government and businessman must anticipate it in order to strengthened Indonesia's economy.

Microstructure of a-C:H films prepared on a microtrench and analysis of ions and radicals behavior

Energy Technology Data Exchange (ETDEWEB)

Hirata, Yuki; Choi, Junho, E-mail: choi@mech.t.u-tokyo.ac.jp [Department of Mechanical Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan)

2015-08-28

Amorphous carbon films (a-C:H) were prepared on a microtrench (4-μm pitch and 4-μm depth), and the uniformity of film thickness and microstructure of the films on the top, sidewall, and bottom surfaces of the microtrench were evaluated by scanning electron microscopy and Raman spectroscopy. The a-C:H films were prepared by bipolar-type plasma based ion implantation and deposition (bipolar PBII&D), and the negative pulse voltage, which is the main parameter dominating the film structure, was changed from −1.0 to −15 kV. Moreover, the behavior of ions and radicals was analyzed simultaneously by combining the calculation methods of Particle-In-Cell/Monte Carlo Collision (PIC-MCC) and Direct Simulation Monte Carlo (DSMC) to investigate the coating mechanism for the microtrench. The results reveal that the thickness uniformity of a-C:H films improves with decreasing negative pulse voltage due to the decreasing inertia of incoming ions from the trench mouth, although the film thickness on the sidewall tends to be much smaller than that on the top and bottom surfaces of the trench. The normalized flux and the film thickness show similar behavior, i.e., the normalized flux or thickness at the bottom surface increases at low negative pulse voltages and then saturates at a certain value, whereas at the sidewall it monotonically decreases with increasing negative voltage. The microstructure of a-C:H films on the sidewall surface is very different from that on the top and bottom surfaces. The film structure at a low negative pulse voltage shifts to more of a polymer-like carbon (PLC) structure due to the lower incident energy of ions. Although the radical flux on the sidewall increases slightly, the overall film structure is not significantly changed because this film formation at a low negative voltage is originally dominated by radicals. On the other hand, the flux of radicals is dominant on the sidewall in the case of high negative pulse voltage, resulting in a

Microstructure of a-C:H films prepared on a microtrench and analysis of ions and radicals behavior

Science.gov (United States)

Hirata, Yuki; Choi, Junho

2015-08-01

Amorphous carbon films (a-C:H) were prepared on a microtrench (4-μm pitch and 4-μm depth), and the uniformity of film thickness and microstructure of the films on the top, sidewall, and bottom surfaces of the microtrench were evaluated by scanning electron microscopy and Raman spectroscopy. The a-C:H films were prepared by bipolar-type plasma based ion implantation and deposition (bipolar PBII&D), and the negative pulse voltage, which is the main parameter dominating the film structure, was changed from -1.0 to -15 kV. Moreover, the behavior of ions and radicals was analyzed simultaneously by combining the calculation methods of Particle-In-Cell/Monte Carlo Collision (PIC-MCC) and Direct Simulation Monte Carlo (DSMC) to investigate the coating mechanism for the microtrench. The results reveal that the thickness uniformity of a-C:H films improves with decreasing negative pulse voltage due to the decreasing inertia of incoming ions from the trench mouth, although the film thickness on the sidewall tends to be much smaller than that on the top and bottom surfaces of the trench. The normalized flux and the film thickness show similar behavior, i.e., the normalized flux or thickness at the bottom surface increases at low negative pulse voltages and then saturates at a certain value, whereas at the sidewall it monotonically decreases with increasing negative voltage. The microstructure of a-C:H films on the sidewall surface is very different from that on the top and bottom surfaces. The film structure at a low negative pulse voltage shifts to more of a polymer-like carbon (PLC) structure due to the lower incident energy of ions. Although the radical flux on the sidewall increases slightly, the overall film structure is not significantly changed because this film formation at a low negative voltage is originally dominated by radicals. On the other hand, the flux of radicals is dominant on the sidewall in the case of high negative pulse voltage, resulting in a deviation

Effect of a nicotine vaccine on nicotine binding to the beta2-nAChRs in vivo in human tobacco smokers

Science.gov (United States)

Esterlis, Irina; Hannestad, Jonas O.; Perkins, Evgenia; Bois, Frederic; D’Souza, D. Cyril; Tyndale, Rachel F.; Seibyl, John P.; Hatsukami, Dorothy M.; Cosgrove, Kelly P.; O’Malley, Stephanie S.

2013-01-01

Objective Nicotine acts in the brain to promote smoking in part by binding to the beta2-containing nicotinic acetylcholine receptors (β2*-nAChRs) and acting in the mesolimbic reward pathway. The effects of nicotine from smoking one tobacco cigarette are significant (80% of β2*-nAChRs occupied for >6h). This likely contributes to the maintenance of smoking dependence and low cessation outcomes. Development of nicotine vaccines provides potential for alternative treatments. We used [123I]5IA-85380 SPECT to evaluate the effect of 3′-AmNic-rEPA on the amount of nicotine that binds to the β2*-nAChRs in the cortical and subcortical regions in smokers. Method Eleven smokers (36years (SD=13); 19cig/day (SD=11) for 10years (SD=7) who were dependent on nicotine (Fagerström Test of Nicotine Dependence score =5.5 (SD=3); plasma nicotine 9.1 ng/mL (SD=5)) participated in 2 SPECT scan days: before and after immunization with 4–400μg doses of 3′-AmNic-rEPA. On SPECT scan days, 3 30-min baseline emission scans were obtained, followed by administration of IV nicotine (1.5mg/70kg) and up to 9 30-min emission scans. Results β2*-nAChR availability was quantified as VT/fP and nicotine binding was derived using the Lassen plot approach. Immunization led to a 12.5% reduction in nicotine binding (F=5.19, df=1,10, p=0.05). Significant positive correlations were observed between nicotine bound to β2*-nAChRs and nicotine injected before but not after vaccination (p=0.05 vs. p=0.98). There was a significant reduction in the daily number of cigarettes and desire for a cigarette (p=.01 and p=.04, respectively). Conclusions This proof-of-concept study demonstrates that immunization with nicotine vaccine can reduce the amount of nicotine binding to β2*-nAChRs and disrupt the relationship between nicotine administered vs. nicotine available to occupy β2*-nAChRs. PMID:23429725

INDUSTRI KREATIF INDONESIA: PENDEKATAN ANALISIS KINERJA INDUSTRI

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Ahmad Kamil

2015-10-01

Full Text Available In 2008, the Department of Commerce of the Republic of Indonesia has launched a creative economic development documents interpreted the 2025 Indonesia became the starting point and guide the development of the creative economy in Indonesia. With the existence of this document, the industry and its stakeholders or other stakeholders can readily develop the creative economy in Indonesia. Economic development in the direction of the creative industries is one manifestation of optimism aspiration to support the Master Plan for the Acceleration and Expansion of Indonesia's Economic Development in realizing the vision of Indonesia are being developed nation. The main objective of this study is the first to analyze the role of the creative industries in Indonesia for labor, value added and productivity, secondly, to analyze the performance trend of the creative industries sector, and third, to analyze the factors affecting the performance of the creative industries sector in Indonesia. Under Indonesia Standard Industrial Classification (ISIC and codes 151-372 (manufacturing industries category identified 18 industry groups belonging to the creative industries, showed that the performance of the national creative industries has been relatively high (in terms of trend analysis of the performance of the industrial creative. Furthermore, regression analysis of panel data (econometrics indicates that company size (SIZE, wages for workers (WAGE and the content of local inputs (LOCAL has a significant impact on the performance of Indonesia's creative industry. Meanwhile, the concentration ratio (CR4 no consequences but have koresi significantly positive effect on the performance of Indonesia’s creative industry.

RAGE mediates the inactivation of nAChRs in sympathetic neurons under high glucose conditions.

Science.gov (United States)

Chandna, Andrew R; Nair, Manoj; Chang, Christine; Pennington, Paul R; Yamamoto, Yasuhiko; Mousseau, Darrell D; Campanucci, Verónica A

2015-02-01

Autonomic dysfunction is a serious complication of diabetes and can lead to cardiovascular abnormalities and premature death. It was recently proposed that autonomic dysfunction is triggered by oxidation-mediated inactivation of neuronal nicotinic acetylcholine receptors (nAChRs), impairing synaptic transmission in sympathetic ganglia and resulting in autonomic failure. We investigated whether the receptor for advanced glycation end products (RAGE) and its role in the generation of reactive oxygen species (ROS) could be contributing to the events that initiate sympathetic malfunction under high glucose conditions. Using biochemical, live imaging and electrophysiological tools we demonstrated that exposure of sympathetic neurons to high glucose increases RAGE expression and oxidative markers, and that incubation with RAGE ligands (e.g. AGEs, S100 and HMGB1) mimics both ROS elevation and nAChR inactivation. In contrast, co-treatment with either antioxidants or an anti-RAGE IgG prevented the inactivation of nAChRs. Lastly, a role for RAGE in this context was corroborated by the lack of sensitivity of sympathetic neurons from RAGE knock-out mice to high glucose. These data define a pivotal role for RAGE in initiating the events associated with exposure of sympathetic neurons to high glucose, and strongly support RAGE signaling as a potential therapeutic target in the autonomic complications associated with diabetes. © 2014 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

PROSES PEMBENTUKAN KOMUNITAS MUSLIM INDONESIA

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Mirhan AM

2014-10-01

Full Text Available This paper is a study in mapping out more about the process of formation of the Muslim community in Indonesia. History is a reconstruct of the past. It seems as if the past was to be away from the present. Is it true that this view. We borrow the Kuntowijoyo’s words: “Historians are like people take who takes the train to look back, and he can freely turn to the right and to the left, which can not be done is to look ahead”. History is a valuable clue, a picture of the past that can be used as guidelines in stride, present and future. The Indonesian Islam history has significance for this nation generation. Because it has its own characteristics compared to the history of Islam in other countries. It can give the feel of the real Islam in Indonesia. The Indonesian Islam is an Islamic hue promising future in the era of globalization. Thus, Indonesian Islam will be in focus in the eyes of the world. In this description, the writer describes the entry and the development of Islam in Indonesia with discussion; process and the introduction of Islam to Indonesia, acceptance by indigenous and institutionalization of Islam in society. Then, point the establishment of Islam in Indonesia, as well as the transformation of Indonesia society

Hepatitis B virus infection in Indonesia.

Science.gov (United States)

Yano, Yoshihiko; Utsumi, Takako; Lusida, Maria Inge; Hayashi, Yoshitake

2015-10-14

Approximately 240 million people are chronically infected with hepatitis B virus (HBV), 75% of whom reside in Asia. Approximately 600000 of infected patients die each year due to HBV-related diseases or hepatocellular carcinoma (HCC). The endemicity of hepatitis surface antigen in Indonesia is intermediate to high with a geographical difference. The risk of HBV infection is high in hemodialysis (HD) patients, men having sex with men, and health care workers. Occult HBV infection has been detected in various groups such as blood donors, HD patients, and HIV-infected individuals and children. The most common HBV subgenotype in Indonesia is B3 followed by C1. Various novel subgenotypes of HBV have been identified throughout Indonesia, with the novel HBV subgenotypes C6-C16 and D6 being successfully isolated. Although a number of HBV subgenotypes have been discovered in Indonesia, genotype-related pathogenicity has not yet been elucidated in detail. Therefore, genotype-related differences in the prognosis of liver disease and their effects on treatments need to be determined. A previous study conducted in Indonesia revealed that hepatic steatosis was associated with disease progression. Pre-S2 mutations and mutations at C1638T and T1753V in HBV/B3 have been associated with advanced liver diseases including HCC. However, drug resistance to lamivudine, which is prominent in Indonesia, remains obscure. Although the number of studies on HBV in Indonesia has been increasing, adequate databases on HBV infection are limited. We herein provided an overview of the epidemiology and clinical characteristics of HBV infection in Indonesia.

PERILAKU KONSUMEN TERHADAP MANGGAARUMANIS DI TIGA KOTA BESAR DI INDONESIA

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Tutik Setyawati

2012-10-01

Full Text Available The value of imports of fruit in Indonesia also continued to increase, and in the reality import of the fruit is not least of which is a tropical fruit that can be grown in this country and has been cultivated on a massive scale by farmers, one of themis mango ofArumanis. On the other hand, consumer behavior tend to be very complex and is influenced by emotions, motives and attitudes.For the reason the understanding of concerning behavior of consumer become relevant because the information generated has aspects to like to (a devise a strategy development, production and marketing of the product, (b compile policy of public related to protection of consumer and producer and (c continue with new ideas to producers to not merely sell products and to consumers to be more careful and prudent in making decisions.Research location is three metropolisincluding especial consumer of horticulture product that is Jakarta (DKI, Bandung ( West Java and Padang ( West Sumatra. Responden of consumer survey is selected household consumer at random. Amount of consumer responder in] third the town is West Java = 123 people; Glorious DKI = 110 West Sumatra and people = 106 people, become totally = 339 people.The main analytical tool used is descriptive statistics, cross tabulation, chi square test and the Kruskal Walls to determine the relationship of various product attributes and socio-economic conditions through the use of SPSS statistical program. The results showed the majority of respondents have age between 30-49 years or are of childbearing age, with the majority of education above high school and is a housewife who works.Somewhat different characteristics occurred in Padang where housewives mostly working (70.8%, education SLTA large enough (61.3%, while in Bandung partially big housewife does not work (53.7%. Taste is an indicator of the most dominant in the purchase arumanis mango, flesh color followed. The first criterion is the most preferred by

List of Orchidaceae collected in 1937 by Dr C. G. G. J. van Steenis in Atjeh (North Sumatra)

NARCIS (Netherlands)

Smith, J.J.

1943-01-01

Platanthera angustata (Bl.) Lndl., Gen. et sp. Orch. (1835), 290; etc. Sumatra: Atjeh, Gajolanden, Poetjoek Angasan, bivouac 1 to 2, 2700 m, blang ground, marshy heath, common (C. G. G. J. van Steenis n. 8350, 28 Jan. 1937). G. Leuser, bivouac 4—5, watershed, 2700—2800 m (C. G. G. J. van Steenis n.

Kriptosporidiosis di Indonesia

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Tri Wijayanti

2017-07-01

Full Text Available ABSTRACTCryptosporidiosis included to waterborne and soil transmited diseases, caused by Cryptosporidium, obligat intraceluller pathogen organism. Cryptosporidium cause intestinal infection of human and animal acute diarrhea. Lung cryptosporidiosis on HIV/AIDS and tuberculosis  patients was reported. Diarrhea still be important health problem because diarrhea was be the third dominant contributor of children morbidity and mortality at some country include Indonesia. Every children have 1,6-2x diarrhea onset annually. Diarrhea cases caused by Cryptosporidium sp parasite was around 4-11%. Focus of this review is  about cryptosporidiosis on children, HIV/AIDS and tuberculosis patients, animal, environment, diagnostic and it’s prevention and control. Cryptosporidium species confirmed in Indonesia are C. wrairi, C. muris,  C. felis, C. hominis, C. meleagridis and C. parvum, indicated that there was a big rule of animal on Cryptosporidium transmission. Cryptosporidium was necessary to be one of diseases diagnose on HIV/AIDS and tuberculosis patients. Transmission of Cryptosporidium by  respiratory secretion (droplet, aerosol or contact with vomiting must be anticipated to prevent cryptosporidiosis especially on imunocompromissed/imunodeficiency people. Rapid Diagnostic Test that have highly sensitivity and spesificity is very important on Cryptosporidium cases finding and surveillance in Indonesia. Environment and cattle sanitation, personal hygiene, water and food treatment, is necessary to prevent cryptosporidiosis transmission.  Kriptosporidiosis termasuk waterborne dan soil transmitted diseases, disebabkan oleh Cryptosporidium yang bersifat obligat intraseluler. Cryptosporidium menyebabkan infeksi pada usus halus dan dapat menyebabkan diare akut pada manusia dan hewan. Kriptosporidiosis paru telah dilaporkan pada penderita HIV/AIDS dan tuberkulosis. Diare merupakan penyumbang utama ketiga angka kesakitan dan kematian anak di berbagai negara

INDUSTRI KREATIF INDONESIA: PENDEKATAN ANALISIS KINERJA INDUSTRI

OpenAIRE

Ahmad Kamil

2015-01-01

In 2008, the Department of Commerce of the Republic of Indonesia has launched a creative economic development documents interpreted the 2025 Indonesia became the starting point and guide the development of the creative economy in Indonesia. With the existence of this document, the industry and its stakeholders or other stakeholders can readily develop the creative economy in Indonesia. Economic development in the direction of the creative industries is one manifestation of optimism aspiration...

SASTRA CYBER DI INDONESIA

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Laily Fitriani

2011-10-01

Full Text Available The digital era started when the internet technology spread to the developing countries including Indonesia. The flourish of cyber literature leads to the debate on the quality of the work of literature. Above all, the existence of literature sites (cyber literature becomes an important alternative for writers and literary activist in Indonesia.

Dinamika Kurikulum di Indonesia

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M. Asri

2017-09-01

Full Text Available Education does not have a standard reference, which covers access for revision by the authorities. Because education continues to grow along with the rolling times. Therefore, all matters relating to education also do not have a standard reference, including educational curriculum. The curriculum is one of the important elements that has a role to advance education in Indonesia, in accordance with the ideals of the constitution. Curriculum changes are not taboo for education in developed countries of the world (such as Japan, Finlandia,  USA, etc.. Basically the dynamics of curriculum in Indonesia aims to make education in Indonesia able to compete with the developed countries in the world.

Peramalan Pengguna Broadband di Indonesia [Forecasting of Broadband Users in Indonesia

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Azwar Aziz

2016-07-01

Full Text Available Negara Indonesia memiliki peluang yang sangat besar untuk merealisasikan potensi pitalebar, mengingat Indonesia memiliki jumlah penduduk 253 juta orang dan pengguna internet 88,1 juta orang pada tahun 2014. Di sisi lain sektor komunikasi (salah satunya termasuk telekomunikasi merupakan satu-satunya sektor yang secara konsisten memberikan kontribusi pertumbuhan terhadap Pendapatan Domestik Bruto (PDB sebesar dua angka (double digit. Kemudian peran penting pemerintah adalah selalu mengantisipasi dalam membuat regulasi telekomunikasi, salah satu nya untuk mempercepat penggelaran prasarana pitalebar, seperti menerbitkan Peraturan Presiden RI. Nomor 96 Tahun 2014 tentang Rencana Pitalebar Indonesia 2014 – 2019.  Secara riil pembangunan jaringan pitalebar di Indonesia masih dilakukan di kota-kota besar, mengingat pengguna telekomunikasi sebagian besar berada di kota-kota besar. Selain itu perangkat hanset atau handphone, ketersediaan di pasaran masih terbatas dan harganya masih mahal. Kajian ini menggunakan metodologi penelitian kuantitatif dengan menghitung peramalan dan kualitatif, dengan melakukan observasi atau pengamatan langsung ke lapangan kepada perusahaan Telkom, Telkomsel, XL Axiata dan Indosat. Selanjutnya hasil penelitian ini diperoleh lima faktor yang mempengaruhi penggunaan pitalebar yaitu jumlah penduduk, produk domestik bruto, pendapatan per kapita, laju pertumbuhan ekonomi dan inflasi, dan laju penetrasi. Selain itu, hasil pitalebar menunjukkan pengguna pitalebar lima tahun kedepan selalu meningkat.*****Indonesia has a tremendous opportunity to implement the potential of broadband, as Indonesia has a population of 253 million people and 88.1 million Internet users in 2014. On the other hand, the communication sector (one of them including telecommunications is the only sector that is consistently contributed to the growth of Gross Domestic Product (GDP as many as two numbers (double-digit. Then the important role of government is

LDC nuclear power: Indonesia

International Nuclear Information System (INIS)

Poneman, D.B.

1982-01-01

Indonesia's five-year plan to develop a research reactor is still in the feasibility stage of a policy to minimize domestic oil consumption. The evolution of a nuclear program in Indonesia illustrates the importance of strong political leadership in developing countries which lack technical skills and political and economic stability and the need for strong international support. 39 references

FINANCIAL DEPTH AND FINANCIAL ACCESS IN INDONESIA

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Sigit Setiawan

2015-05-01

Full Text Available This study is intended to analyze the current levels of financial depth and financial access in Indonesia and to analyze the factors affecting them. The analysis method used was a combination of descriptive quantitative, benchmarking, and literature reviews. The conclusion is that the financial depth in Indonesia has not shown a satisfactory level since it was the lowest, or the second lowest ranked country among the sampled countries. Meanwhile, the financial access in Indonesia is relatively better than its financial depth, especially for financial markets, in which Indonesia ranks in the lower average group. From literature reviews, it can be inferred that the main factor driving the poor financial depth in Indonesia is non-competitiveness of the institutions; whereas the driving force of poor financial access in Indonesia are geographical constraints, poverty, a high income gap, and a less than effective national financial development policy.

DAYA SAING KAKAO INDONESIA DI PASAR INTERNASIONAL

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Anggita Tresliyana

2015-07-01

Full Text Available Cocoa is one of the major Indonesian agricultural export products. Cocoa international market has great potential regarding world’s consumption growth, therefore Indonesia is expected to take advantage on existing opportunities. The aims of this study were to analyze the competitiveness of Indonesian cocoa beans and processed cocoa trade in the international market as well as the level of competition between cocoa exporting countries. By using Revealed Comparative Advantage (RCA and Spearman Rank Correlation, it showed that Indonesia had a comparative advantage as an cocoa exporter on the international market, the highest for cocoa beans and the lowest for cocoa paste; Indonesia also had a significant correlation to exporting countries in cocoa beans’ market (Ghana and cocoa paste’s market (Netherlands and Malaysia, the correlation suggests that there were high correlation between Indonesia and the exporting country in competing for market share.Keywords: cocoa, comparative advantage, international trade, competitiveness, market share, RCA ABSTRAKKakao merupakan salah satu komoditas pertanian unggulan ekspor Indonesia.  Pasar kakao memiliki potensi yang besar dilihat dari peningkatan konsumsi dunia, sehingga Indonesia diharapkan dapat memanfaatkan peluang yang ada.  Tujuan penelitian ini adalah menganalisis daya saing perdagangan biji kakao dan kakao olahan Indonesia di pasar internasional serta hubungan daya saing antar negara eksportir kakao. Dengan menggunakan Reavealed Comparative Advantage (RCA, dan Korelasi Rank Spearman, hasil analisis menunjukkan bahwa Indonesia memiliki keunggulan komparatif sebagai eksportir biji kakao dan kakao olahan di pasar internasional, tertinggi untuk biji kakao dan terendah untuk kakao pasta;  Indonesia juga memiliki korelasi yang signifikan di beberapa negara untuk pasar biji kakao (Ghana dan kakao pasta (Belanda dan Malaysia, korelasi tersebut menunjukkan bahwa terdapat hubungan daya saing yang cukup

Effectiveness of Interactive Multimedia Based Learning Model in Engineering Mechanics

Science.gov (United States)

Tambunan, Hamonangan; Napitupulu, Efendi

2016-01-01

Now the demand for skilled labor is urgent. Development of skilled labor has been done in various ways either through education and training. Indonesia, especially North Sumatra state nurture some vocational schools that produce graduates which are expected to be ready for working, but have not been able to meet these expectations. Therefore we…

Developing Learning Model Based on Local Culture and Instrument for Mathematical Higher Order Thinking Ability

Science.gov (United States)

Saragih, Sahat; Napitupulu, E. Elvis; Fauzi, Amin

2017-01-01

This research aims to develop a student-centered learning model based on local culture and instrument of mathematical higher order thinking of junior high school students in the frame of the 2013-Curriculum in North Sumatra, Indonesia. The subjects of the research are seventh graders which are taken proportionally random consisted of three public…

Land of Hope and Land of the Lost: Study of Power Relations and Local Wisdom Ethnic Lampung, Sumatra, Indonesia

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Bartoven Vivit Nurdin

2018-01-01

Full Text Available This paper examines the marginalization of indigenous lands belonging to Lampung ethnic group and changes in power relations between Java and Lampung ethnic groups. Lampung has been the destination area of colonization since 1905 and was followed by transmigration of Javanese. The turnout of population from Java in Lampung was a part of the program of development distribution and poverty alleviation in Indonesia. The impact of the arrival of Javanese to Lampung is the marginalization of indigenous lands in Lampung. The lands in Lampung have been largely controlled by the new comers and the plantation companies growing in Lampung. The relationship between Javanese and Lampung ethnic groups has also given an effect to this marginalization. The research used qualitative method with ethnographic approach. The data were collected through in-depth interviews and participative observation. The results of this investigation indicate that the marginalization of land belonging to Lampung ethnic group occurs in such a way that not realized by the Lampungnese or may due to the change of the views of Lampungnese on the meaning of "power”. A power over a land has no longer described the real power, but the power in the political system and the local bureaucracy does. Lampung ethnic group also experienced extinction in the culture, except the identity of the "self-esteem" which has been actualized in form of power in local politics.

Regional air quality impacts of future fire emissions in Sumatra and Kalimantan

Science.gov (United States)

Marlier, Miriam E.; DeFries, Ruth S.; Kim, Patrick S.; Gaveau, David L. A.; Koplitz, Shannon N.; Jacob, Daniel J.; Mickley, Loretta J.; Margono, Belinda A.; Myers, Samuel S.

2015-05-01

Fire emissions associated with land cover change and land management contribute to the concentrations of atmospheric pollutants, which can affect regional air quality and climate. Mitigating these impacts requires a comprehensive understanding of the relationship between fires and different land cover change trajectories and land management strategies. We develop future fire emissions inventories from 2010-2030 for Sumatra and Kalimantan (Indonesian Borneo) to assess the impact of varying levels of forest and peatland conservation on air quality in Equatorial Asia. To compile these inventories, we combine detailed land cover information from published maps of forest extent, satellite fire radiative power observations, fire emissions from the Global Fire Emissions Database, and spatially explicit future land cover projections using a land cover change model. We apply the sensitivities of mean smoke concentrations to Indonesian fire emissions, calculated by the GEOS-Chem adjoint model, to our scenario-based future fire emissions inventories to quantify the different impacts of fires on surface air quality across Equatorial Asia. We find that public health impacts are highly sensitive to the location of fires, with emissions from Sumatra contributing more to smoke concentrations at population centers across the region than Kalimantan, which had higher emissions by more than a factor of two. Compared to business-as-usual projections, protecting peatlands from fires reduces smoke concentrations in the cities of Singapore and Palembang by 70% and 40%, and by 60% for the Equatorial Asian region, weighted by the population in each grid cell. Our results indicate the importance of focusing conservation priorities on protecting both forested (intact or logged) peatlands and non-forested peatlands from fire, even after considering potential leakage of deforestation pressure to other areas, in order to limit the impact of fire emissions on atmospheric smoke concentrations and

Regional air quality impacts of future fire emissions in Sumatra and Kalimantan

International Nuclear Information System (INIS)

Marlier, Miriam E; DeFries, Ruth S; Kim, Patrick S; Koplitz, Shannon N; Jacob, Daniel J; Gaveau, David L A; Mickley, Loretta J; Margono, Belinda A; Myers, Samuel S

2015-01-01

Fire emissions associated with land cover change and land management contribute to the concentrations of atmospheric pollutants, which can affect regional air quality and climate. Mitigating these impacts requires a comprehensive understanding of the relationship between fires and different land cover change trajectories and land management strategies. We develop future fire emissions inventories from 2010–2030 for Sumatra and Kalimantan (Indonesian Borneo) to assess the impact of varying levels of forest and peatland conservation on air quality in Equatorial Asia. To compile these inventories, we combine detailed land cover information from published maps of forest extent, satellite fire radiative power observations, fire emissions from the Global Fire Emissions Database, and spatially explicit future land cover projections using a land cover change model. We apply the sensitivities of mean smoke concentrations to Indonesian fire emissions, calculated by the GEOS-Chem adjoint model, to our scenario-based future fire emissions inventories to quantify the different impacts of fires on surface air quality across Equatorial Asia. We find that public health impacts are highly sensitive to the location of fires, with emissions from Sumatra contributing more to smoke concentrations at population centers across the region than Kalimantan, which had higher emissions by more than a factor of two. Compared to business-as-usual projections, protecting peatlands from fires reduces smoke concentrations in the cities of Singapore and Palembang by 70% and 40%, and by 60% for the Equatorial Asian region, weighted by the population in each grid cell. Our results indicate the importance of focusing conservation priorities on protecting both forested (intact or logged) peatlands and non-forested peatlands from fire, even after considering potential leakage of deforestation pressure to other areas, in order to limit the impact of fire emissions on atmospheric smoke concentrations

INFLASI DI INDONESIA : SUMBER-SUMBER PENYEBAB DAN PENGENDALIANNYA

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Adwin Surja Atmadja

1999-01-01

Full Text Available The monetary crisis that happens among the ASEAN countries including Indonesia has cause the broken of the national economical aspects. The monetary crisis causes the imported inflation, which is the result of the sharp depreciation of rupiah exchange rate toward the foreign exchange rate. This condition can cause the heavy inflation pressure for Indonesia. The inflation phenomenon in Indonesia actually is not the short-term phenomena. That is only happens incidentally. In fact, the same general problem also happens in others developing countries. The inflation problem in Indonesia is the kind of long-term inflation that caused by the structural of economic obstacles that still occur in Indonesia. As the result, the reconstruction of inflation problem in Indonesia is not enough to be accomplished only with monetary instruments, which usually tend to be in short-term. Therefore, the reconstruction in the real sector with the main target to eliminate the nation structural economic obstacles also needed in order to improve the national economy of Indonesia. Abstract in Bahasa Indonesia : Krisis moneter yang melanda negara-negara ASEAN, termasuk Indonesia, telah menyebabkan rusaknya sendi-sendi perekonomian nasional. Krisis moneter menyebabkan terjadinya imported inflation sebagai akibat dari terdepresiasinya secara tajam nilai tukar rupiah terhadap mata uang asing, yang selanjutnya mengakibatkan tekanan inflasi yang berat bagi Indonesia. Fenomena inflasi di Indonesia sebenarnya semata-mata bukan merupakan suatu fenomena jangka pendek saja dan yang terjadi secara situasional, tetapi seperti halnya yang umum terjadi pada negara-negara yang sedang berkembang lainnya, masalah inflasi di Indonesia lebih pada masalah inflasi jangka panjang karena masih terdapatnya hambatan-hambatan struktural dalam perekonomian negara. Dengan demikian, maka pembenahan masalah inflasi di Indonesia tidak cukup dilakukan dengan menggunakan instrumen-instrumen moneter saja

INTELLECTUAL PROPERTY LAW IN INDONESIA AFTER 2001

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Valerie Selvie Sinaga

2013-04-01

Full Text Available This paper reviews the major changes of intellectual property condition in Indonesia after 2001. In that year, Indonesia, which has become a member of the Agreement on Trade Related Aspects of Intellectual Property Rights (TRIPS since 1994, was ready to meet its commitment under TRIPS. To do so, Indonesiahas made changes in the areas of legislation, administration, court proceedings, and law enforcement. The paper also discusses problematic issues surrounded the implementation of such changes in Indonesia. Tulisan ini melihat kembali perubahan-perubahan besar dalam bidang hak kekayaan intelektual di Indonesia setelah tahun 2001. Pada tahun tersebut, Indonesia, yang telah menjadi anggota Agreement on Trade Related Aspects of Intellectual Property Rights (TRIPS sejak 1994, siap untuk memenuhi komitmennya dalam TRIPS. Untuk memenuhi komitmen tersebut, Indonesia telah membuat perubahan-perubahan dalam bidang legislatif, administratif, tata cara pengadilan dan penegakan hukum. Tulisan ini juga membahas permasalahan di seputar pelaksanaan perubahan-perubahan tersebut.

Indonesia-DLN Is A Digital Library Network In Indonesia

International Nuclear Information System (INIS)

Fahmi, Ismail

2001-01-01

Within this paper, philosophy of the knowledge sharing, vision of the network, and how it can give benefits to Indonesia are described. The status of the network is described that show the successfulness of the architecture in tying together partner's knowledge from all big islands of Indonesia (Sumatera, Java, Kalimantan, Sulawesi, and Irian Jaya) whether they have dedicated internet connection or only a dial-up one. Currently 13 institutions have joined the network and 15+ in progress of developing their servers. Features of the software, Ganesha Digital Library (GDL version 3.1) are presented, that is now distributed as a Free-Software that is based on My SQL, PHP, and Apache

THE MEDICALLY IMPORTANT MOLLUSCS OF INDONESIA

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Machfudz Djajasasmita

2012-09-01

Full Text Available At present in Indonesia 32 species of non-marine molluscs which belong to IS families have been known to be potentially of medicalor veterinary importance, since they are suspected to be capable in transmitting human and animal diseases. The brackish water family Potamididae comprises of 1 species; whereas the freshwater snails are : Viviparidae (3 sp., Ampullariidae (3 sp., Bythiniidae (1 sp.. Pomatiopsidae (1 sp., Thiaridae (7 sp., Lymnaeidae(l sp. and Planorbidae (5 sp.; freshwater bivalve are: Corbiculidae (4 sp.; land snails are: Subulinidae (2 sp., Achatinidae (1 sp. and Bradybaenidae (1 sp.; land slug: Veronicelidae (2 sp. Philomycidae (1 sp. and Limacidae (1 sp.. All are common species which can be found in the vicinity of human habitation (ponds, rice-field, ditches, gardens etc. The parasitological studies on these molluscs are rather limited, only 9 species have been studied and confirmed to be the intermediate host of parasitic nematodes and nematodes; i.e. Oncomelania hupensis lindoensis, the intermediate host of the blood fluke Schistosoma japonica in Central Sulawesi: Pila suctata, Achatina fulica and Laevicaulis alte from several places in Sumatra, Java, Sulawesi and Flores have been found to be harbouring the larvae of the nematode Angiostrongylus cantonensis, the causative agent of eosinophilic meningoencephalitis; Bellamy a rudipelis, Gyraulus sarasinorum and Corbicula lindoensis were recorded as the intermediate host of the intestinal fluke Echinostoma lindoensis in Central Sulawesi; Lymnaea rubiginosa plays an important role in the life-cycle of the cattle liver fluke Fasciola gigantica and F.hepatica, which may reduce the national meat production; and Digoniostoma truncatum from Bali has been recorded naturally infected with radiae and cercariae of Paramphistoma sp., the causative agent of the fatal paramphistomiasis of cattle. Gyraulus convexiusculus is considered to be the most likely first intermediate host of

Cigarette smoking during pregnancy regulates the expression of specific nicotinic acetylcholine receptor (nAChR) subunits in the human placenta

Energy Technology Data Exchange (ETDEWEB)

Machaalani, R., E-mail: rita.machaalani@sydney.edu.au [Department of Medicine, The University of Sydney, NSW 2006 (Australia); Bosch Institute, The University of Sydney, NSW 2006 (Australia); The Children' s Hospital at Westmead, NSW 2145 (Australia); Ghazavi, E. [Bosch Institute, The University of Sydney, NSW 2006 (Australia); School of Medical Sciences (Pharmacology), The University of Sydney, NSW 2006 (Australia); Hinton, T. [School of Medical Sciences (Pharmacology), The University of Sydney, NSW 2006 (Australia); Waters, K.A. [Department of Medicine, The University of Sydney, NSW 2006 (Australia); The Children' s Hospital at Westmead, NSW 2145 (Australia); Hennessy, A. [School of Medicine, University of Western Sydney, NSW 2751 (Australia); Heart Research Institute, 7 Eliza St Newtown, NSW 2042 (Australia)

2014-05-01

Smoking during pregnancy is associated with low birth weight, premature delivery, and neonatal morbidity and mortality. Nicotine, a major pathogenic compound of cigarette smoke, binds to the nicotinic acetylcholine receptors (nAChRs). A total of 16 nAChR subunits have been identified in mammals (9 α, 4 β, and 1 δ, γ and ε subunits). The effect of cigarette smoking on the expression of these subunits in the placenta has not yet been determined, thus constituting the aim of this study. Using RT-qPCR and western blotting, this study investigated all 16 mammalian nAChR subunits in the normal healthy human placenta, and compared mRNA and protein expressions in the placentas from smokers (n = 8) to controls (n = 8). Our data show that all 16 subunit mRNAs are expressed in the normal, non-diseased human placenta and that the expression of α2, α3, α4, α9, β2 and β4 subunits is greater than the other subunits. For mRNA, cigarette smoke exposure was associated with increased expression of the α9 subunit, and decreased expression of the δ subunit. At the protein level, expression of both α9 and δ was increased. Thus, cigarette smoking in pregnancy is sufficient to regulate nAChR subunits in the placenta, specifically α9 and δ subunits, and could contribute to the adverse effects of vasoconstriction and decreased re-epithelialisation (α9), and increased calcification and apoptosis (δ), seen in the placentas of smoking women. - Highlights: • All 16 mammalian nAChR subunits are expressed in the human placenta. • Cigarette smoking increases α9 mRNA and protein in the placenta. • Cigarette smoking decreases δ mRNA but increases δ protein in the placenta.

Cigarette smoking during pregnancy regulates the expression of specific nicotinic acetylcholine receptor (nAChR) subunits in the human placenta

International Nuclear Information System (INIS)

Machaalani, R.; Ghazavi, E.; Hinton, T.; Waters, K.A.; Hennessy, A.

2014-01-01

Smoking during pregnancy is associated with low birth weight, premature delivery, and neonatal morbidity and mortality. Nicotine, a major pathogenic compound of cigarette smoke, binds to the nicotinic acetylcholine receptors (nAChRs). A total of 16 nAChR subunits have been identified in mammals (9 α, 4 β, and 1 δ, γ and ε subunits). The effect of cigarette smoking on the expression of these subunits in the placenta has not yet been determined, thus constituting the aim of this study. Using RT-qPCR and western blotting, this study investigated all 16 mammalian nAChR subunits in the normal healthy human placenta, and compared mRNA and protein expressions in the placentas from smokers (n = 8) to controls (n = 8). Our data show that all 16 subunit mRNAs are expressed in the normal, non-diseased human placenta and that the expression of α2, α3, α4, α9, β2 and β4 subunits is greater than the other subunits. For mRNA, cigarette smoke exposure was associated with increased expression of the α9 subunit, and decreased expression of the δ subunit. At the protein level, expression of both α9 and δ was increased. Thus, cigarette smoking in pregnancy is sufficient to regulate nAChR subunits in the placenta, specifically α9 and δ subunits, and could contribute to the adverse effects of vasoconstriction and decreased re-epithelialisation (α9), and increased calcification and apoptosis (δ), seen in the placentas of smoking women. - Highlights: • All 16 mammalian nAChR subunits are expressed in the human placenta. • Cigarette smoking increases α9 mRNA and protein in the placenta. • Cigarette smoking decreases δ mRNA but increases δ protein in the placenta

Island history affects faunal composition: the treeshrews (Mammalia: Scandentia: Tupaiidae) from the Mentawai and Batu Islands, Indonesia

Science.gov (United States)

Sargis, Eric J.; Woodman, Neal; Morningstar, Natalie C.; Reese, Aspen T.; Olson, Link E.

2014-01-01

The Mentawai and Batu Island groups off the west coast of Sumatra have a complicated geological and biogeographical history. The Batu Islands have shared a connection with the Sumatran ‘mainland’ during periods of lowered sea level, whereas the Mentawai Islands, despite being a similar distance from Sumatra, have remained isolated from Sumatra, and probably from the Batu Islands as well. These contrasting historical relationships to Sumatra have influenced the compositions of the respective mammalian faunas of these island groups. Treeshrews (Scandentia, Tupaiidae) from these islands have, at various times in their history, been recognized as geographically circumscribed populations of a broadly distributed Tupaia glis, subspecies, or distinct species. We used multivariate analyses of measurements from the skull and hands to compare the island populations from Siberut (Mentawai Islands) and Tanahbala (Batu Islands) with the geographically adjacent species from the southern Mentawai Islands (T. chrysogaster) and Sumatra (T. ferruginea). Results from both the skull and manus of the Siberut population show that it is most similar to T. chrysogaster, whereas the Tanahbala population is more similar to T. ferruginea, confirming predictions based on island history. These results are further corroborated by mammae counts. Based on these lines of evidence, we include the Siberut population in T. chrysogaster and the Tanahbala population in T. ferruginea. Our conclusions expand the known distributions of both the Mentawai and Sumatran species. The larger geographical range of the endangered T. chrysogaster has conservation implications for this Mentawai endemic, so populations and habitat should be re-evaluated on each of the islands it inhabits. However, until such a re-evaluation is conducted, we recommend that the IUCN Red List status of this species be changed from ‘Endangered’ to ‘Data Deficient’.

Kinetics of Hydrocarbon formation in a-C:H film deposition plasmas

International Nuclear Information System (INIS)

De la Cal, E.; Tabares, F.L.

1993-01-01

The formation of C 2 and C 3 hydrocarbons during the PACVD of a-C-H films from admixtures of methane with H 2 and He has been investigated by mass spectrometry under several deposition condition. The time evolution of the observed species indicates that the formation mechanism of ethylene and acetylene are sensitive to the conditions of the wall during the growing of the film. Acetylene are sensitive to the conditions of the wall during the growing of the carburized metal. (Author)

EKSISTENSI OMBUDSMAN REPUBLIK INDONESIA

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yusnani hasjimzoem

2015-11-01

Full Text Available Republic of Indonesia is a rule of law under Article 1 (3 of the 1945 Constitution and should uphold respect for the rights of individuals and communities in implementing the country. The rights strengthened by the basic norms that become the main spirit of the people of Indonesia, Pancasila. Basic norms that the political objectives in developing the Indonesian nation and enact any bill. Thus the state agency that was created by a special law should work in line with the basic norms of the nation and work together to create prosperity. In 2003 the Ombudsman created by a special law has the duty and function to oversee public services effectively, efficiently, and in spite of the practice of (corruption, collusion, and nepotism. Ombudsman based its duties and functions that have the same vision as mandated in the fourth paragraph of the preamble of the Constitution of 1945. The Ombudsman is thus expected to make a good bureaucratic reform so that it can be a model and public services watchdog whose presence is really felt by the people of Indonesia. Keywords: Ombudsman of the Republic of Indonesia

The Continuity and the Culture Change of Pesantren in South Sumatra

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Munir Munir

2016-09-01

Full Text Available This article entitled culture of pesantren (madrasah boarding schools in South Sumatra. This article is the result of research in Pesantren Nurul Islam Ogan Ilir South Sumatra. It is based on the fact that many pesantren graduation create academicians from the Kiayi or Ulama. Therefore, this paper describe the characteristics of the culture of madrasah schools from anthropology-sociology aspects of education, with a phenomenological approach to research subjects are madrasah chairman, board of teachers, students and community supporters. The data collection techniques used documentation study, observation and in-depth interviews, and analysis of data using qualitative descriptive, with triangulation and contrasting techniques. Applying local knowledge systems in boarding school curriculum and integrated with Madrasah boarding school curriculum. Orientation discipline tends towards positive law than the laws of Personality Syara’. Clothing the students follow a uniform generally used in madrasah. For students wear clothes instead of the veil of windings. Artistic activities undertaken include: litany, muhad Barzanji, Tilawah al-Qur’an, calligraphy, and drum band.   Artikel berjudul budaya pesantren (sekolah berasrama madrasah di Sumatera Selatan. Artikel ini merupakan hasil penelitian di Pesantren Nurul Islam Ogan Ilir Sumatera Selatan. Hal ini didasarkan pada kenyataan bahwa banyak lulusan pesantren melahirkan akademisi dari kiayi atau Ulama. Oleh karena itu, makalah ini menggambarkan karakteristik budaya dari sekolah madrasah dari aspek antropologi-sosiologi pendidikan, dengan pendekatan fenomenologis dengan subyek penelitian kepala madrasah, dewan guru, siswa dan masyarakat sekitar. Teknik pengumpulan data yang digunakan studi dokumentasi, observasi dan wawancara mendalam, dan analisis data menggunakan deskriptif kualitatif, dengan triangulasi dan teknik kontras. Menerapkan sistem pengetahuan lokal dalam kurikulum pesantren dan

KAJIAN BISNIS FRANCHISE MAKANAN DI INDONESIA

OpenAIRE

Dewi Astuti

2005-01-01

Food franchising business in Indonesia is growing up very fast. Factors that urge the growth are the specific characteristics of franchise inself, the rise of market demand, the availability of skilled labor, the high of return on investment and the internal factors such as the motivation, personality and the changing life style. Abstract in Bahasa Indonesia : Bisnis franchise makanan di Indonesia berkembang dengan cepat. Beberapa faktor yang mendorong pertumbuhannya adalah ciri-ciri dari fra...

The 2007 Mentawai earthquake sequence on the Sumatra megathrust

Science.gov (United States)

Konca, A.; Avouac, J.; Sladen, A.; Meltzner, A. J.; Kositsky, A. P.; Sieh, K.; Fang, P.; Li, Z.; Galetzka, J.; Genrich, J.; Chlieh, M.; Natawidjaja, D. H.; Bock, Y.; Fielding, E. J.; Helmberger, D. V.

2008-12-01

The Sumatra Megathrust has recently produced a flurry of large interplate earthquakes starting with the giant Mw 9.15, Aceh earthquake of 2004. All of these earthquakes occurred within the area monitored by the Sumatra Geodetic Array (SuGAr), which provided exceptional records of near-field co-seismic and postseismic ground displacements. The most recent of these major earthquakes, an Mw 8.4 earthquake and an Mw 7.9 earthquake twelve hours later, occurred in the Mentawai islands area where devastating historical earthquakes had happened in 1797 and 1833. The 2007 earthquake sequence provides an exceptional opportunity to understand the variability of the earthquakes along megathrusts and their relation to interseismic coupling. The InSAR, GPS and teleseismic modeling shows that 2007 earthquakes ruptured a fraction of the strongly coupled Mentawai patch of the megathrust, which is also only a fraction of the 1833 rupture area. It also released a much smaller moment than the one released in 1833, or than the deficit of moment that has accumulated since. Both earthquakes of 2007 consist of 2 sub-events which are 50 to 100 km apart from each other. On the other hand, the northernmost slip patch of 8.4 and southern slip patch of 7.9 earthquakes abut each other, but they ruptured 12 hours apart. Sunda megathrust earthquakes of recent years include a rupture of a strongly coupled patch that closely mimics a prior rupture of that patch and which is well correlated with the interseismic coupling pattern (Nias-Simeulue section), as well as a rupture sequence of a strongly coupled patch that differs substantially in the details from its most recent predecessors (Mentawai section). We conclude that (1) seismic asperities are probably persistent features which arise form heterogeneous strain build up in the interseismic period; and (2) the same portion of a megathrust can rupture in different ways depending on whether asperities break as isolated events or cooperate to produce

Assessment Of Carbon Leakage In Multiple Carbon-Sink Projects: ACase Study In Jambi Province, Indonesia

Energy Technology Data Exchange (ETDEWEB)

Boer, Rizaldi; Wasrin, Upik R.; Hendri, Perdinan; Dasanto,Bambang D.; Makundi, Willy; Hero, Julius; Ridwan, M.; Masripatin, Nur

2007-06-01

Rehabilitation of degraded forest land throughimplementation of carbon sink projects can increase terrestrial carbonstock. However, carbon emissions outside the project boundary, which iscommonly referred to as leakage, may reduce or negate the sequestrationbenefits. This study assessed leakage from carbon sink projects thatcould potentially be implemented in the study area comprised of elevensub-districts in the Batanghari District, Jambi Province, Sumatra,Indonesia. The study estimates the probability of a given land use/coverbeing converted into other uses/cover, by applying a logit model. Thepredictor variables were: proximity to the center of the land use area,distance to transportation channel (road or river), area of agriculturalland, unemployment (number of job seekers), job opportunities, populationdensity and income. Leakage was estimated by analyzing with and withoutcarbon sink projects scenarios. Most of the predictors were estimated asbeing significant in their contribution to land use cover change. Theresults of the analysis show that leakage in the study area can be largeenough to more than offset the project's carbon sequestration benefitsduring the period 2002-2012. However, leakage results are very sensitiveto changes of carbon density of the land uses in the study area. Byreducing C-density of lowland and hill forest by about 10 percent for thebaseline scenario, the leakage becomes positive. Further data collectionand refinement is therefore required. Nevertheless, this study hasdemonstrated that regional analysis is a useful approach to assessleakage.

PROBLEM IDENTIFICATION OF FOREIGN TOURIST DISTRIBUTION IN INDONESIA

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Supriono

2017-07-01

Full Text Available Indonesia should be able to distribute evenly the visits of foreign tourists so that the visit is not merely focused on certain places. It is expected that all the tourism objects in Indonesia can attract and be visited by foreign tourists with the same quantity or number in every tourist destination. In the first year, this study aimed to identify the motivation of foreign tourists visiting Indonesia and identify the problems of distribution of foreign tourists in Indonesia. The study sites were in DKI Jakarta, Batam, and Bali. In the second year later, a distribution channel strategy will be developed in order to create competiveness of tourism. This study was conducted using qualitative research methods with descriptive analysis. The data were collected using in-depth interviews with tourism stakeholders (the Government, International Travelers, and Tourism Bureau/Travel Agencies. The research results show that the motivation of foreign tourists visiting Indonesia was related to business and purely on vacation. Additionally, the problems of foreign tourist distribution in Indonesia emerged because of some aspects, including limited entrance of foreign tourists to Indonesia, lack of connectivity between airports in Indonesia and international flights, lack of inter-regional cooperation between tourism actors, lack of infrastructure, and the ignorance of foreign tourists to all tourist destinations in Indonesia due to less effective and efficient promotion activities.

Understanding Earthquakes

Science.gov (United States)

Davis, Amanda; Gray, Ron

2018-01-01

December 26, 2004 was one of the deadliest days in modern history, when a 9.3 magnitude earthquake--the third largest ever recorded--struck off the coast of Sumatra in Indonesia (National Centers for Environmental Information 2014). The massive quake lasted at least 10 minutes and devastated the Indian Ocean. The quake displaced an estimated…

Radiocesium monitoring in Indonesian waters of the Indian Ocean after the Fukushima nuclear accident

International Nuclear Information System (INIS)

Suseno, Heny; Wahono, Ikhsan Budi; Muslim

2015-01-01

Highlights: • The accident at Fukushima becomes public concern in Indonesia. • Very few data on anthropogenic radionuclide concentrations in marine areas. • Monitoring have been performed at West Sumatra Sea and South Java Sea. - Abstract: As data on anthropogenic radionuclide concentrations (i.e., 134 Cs and 137 Cs) in Indonesian marine environments including the Indian Ocean are scarce, offshore monitoring has been performed in the West Sumatra and South Java Seas. The activity concentration of 137 Cs ranges from below minimum detectable activity (MDA) to 0.13 Bq m −3 in the surface seawater of the South Java Sea and from lower than MDA to 0.28 Bq m −3 in the surface seawater of the West Sumatra Sea. The concentrations of 137 Cs in the surface seawater of the West Sumatra and South Java Seas are lower than the estimation of 137 Cs concentration in the subsurface waters owing to the input of the North Pacific Ocean via the Indonesian Throughflow (ITF). The concentrations of 134 Cs in the sampling locations were lower than MDA. These results have indicated that these Indonesian marine waters have not yet been influenced by the Fukushima radioactive release

AIC-based diffraction stacking for local earthquake locations at the Sumatran Fault (Indonesia)

Science.gov (United States)

Hendriyana, Andri; Bauer, Klaus; Muksin, Umar; Weber, Michael

2018-05-01

We present a new workflow for the localization of seismic events which is based on a diffraction stacking approach. In order to address the effects from complex source radiation patterns, we suggest to compute diffraction stacking from a characteristic function (CF) instead of stacking the original waveform data. A new CF, which is called in the following mAIC (modified from Akaike Information Criterion) is proposed. We demonstrate that both P- and S-wave onsets can be detected accurately. To avoid cross-talk between P and S waves due to inaccurate velocity models, we separate the P and S waves from the mAIC function by making use of polarization attributes. Then, the final image function is represented by the largest eigenvalue as a result of the covariance analysis between P- and S-image functions. Results from synthetic experiments show that the proposed diffraction stacking provides reliable results. The workflow of the diffraction stacking method was finally applied to local earthquake data from Sumatra, Indonesia. Recordings from a temporary network of 42 stations deployed for nine months around the Tarutung pull-apart basin were analysed. The seismic event locations resulting from the diffraction stacking method align along a segment of the Sumatran Fault. A more complex distribution of seismicity is imaged within and around the Tarutung basin. Two lineaments striking N-S were found in the centre of the Tarutung basin which support independent results from structural geology.

Crustal contamination processes traced by helium isotopes: Examples from the Sunda arc, Indonesia

Science.gov (United States)

Gasparon, M.; Hilton, D. R.; Varne, R.

1994-08-01

Helium isotope data have been obtained on well-characterised olivine and clinopyroxene phenocrysts and xenocrysts from thirteen volcanic centres located between central Sumatra and Sumbawa in the Sunda arc of Indonesia. Olivine crystals in mantle xenoliths (Iherzolite) from Bukit Telor basalts are primitive (Mg# = 90), and their He-3/He-4 value (R/R(sub A) = 8.8) indicates that the Sumatran mantle wedge is MORB-like in helium isotope composition. All other samples have lower He-3/He-4 ratios ranging from 8.5R(sub A) to 4.5R(sub A), with most (thirteen out of eighteen) following a trend of more radiogenic He-3/He-4 values with decreasing Mg#. The only exceptions to this trend are phenocrysts from Batur, Agung and Kerinci, which have MORB-like He-3/He-4 values but relatively low Mg# (Mg# = 70-71), and two highly inclusion-rich clinopyroxenes which have He-3/He-4 values lower than other samples of similar Mg#. The results indicate that crustal contamination unrelated to subduction in the Sunda arc is clearly recorded in the He-3/He-4 characteristics of mafic phenocrysts of subaerial volcanics, and that addition of radiogenic helium is related to low-pressure differentiation processes affecting the melts prior to eruption. These conclusions may have widespread applicability and indicate that helium isotope variations can act as an extremely sensitive tracer of upper crustal contamination.

7. Efektivitas Ecpat Indonesia Dalam Menangani Kejahatan Child Sex Tourism Di Indonesia: Studi Kasus Child Sex Tourism Di Bali Tahun 2012 -2014

OpenAIRE

Rizky Irawan, Noor Fathia; Susiatiningsih, Hermini; Paramasatya, Satwika

2016-01-01

The crime of child sex tourism in Bali making Indonesia was rated as the country's firstworld sex tourism, it is triggered by a lack of knowledge and lack of strong laws inIndonesia for the offender. Child sex tourism is a threat to children, since the perpetratorsare mostly foreign pedophiles who come on holiday to Indonesia. To overcome thisproblem ECPAT Indonesia undertaking various efforts to assist Indonesia in dealing withchild sex tourism crimes in particular areas of Bali. ECPAT Inter...

PERKEMBANGAN ISLAM DI INDONESIA PASCA KEMERDEKAAN

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Beti Yanuri Posha

2015-08-01

Full Text Available Islam is a religion that put the principles of truth and justice for all its adherents. Factors that encourage Muslims to achieve independence are factors Ideology, political, economic, social and cultural. In Indonesia, Islam has an important role in education. Islamic education in Indonesia is given in three sectors, namely formal, informal and non-formal. After Indonesian independence, the issue of religious education received serious attention from the government, both in public and private schools, and has established educational institutions, especially schools and a mosque which has become a bastion of Islam that is so strong effect. Therefore, it is important to reassess how the development of Islam in Indonesia as well as the development of Islamic education institutions in Indonesia after independence.

Analisis Keunggulan Bersaing Nissan di Indonesia

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lim Sanny

2010-11-01

Full Text Available Automotive sales in Indonesia picked up sharply in 2010, and increase of prices does not lower the demand for automotive products. The large population of Indonesia and the low level of car ownership in the country suggest there is a lot of potential for expansion in the automotive industry. The aim of this research is to observe Nissan’s strategy in Indonesia to gain a spot in the top 10 of the best automotive seller in Indonesia. This research uses primary data with forecasting with monthly index to forecast the demand and to detect the selling target plans in 2010. Then, with combined porter five forces to determine the competitive strategy in the last 5 years. 

Deforestation Profile of Regency Level In Sumatra

OpenAIRE

Rijal, Syamsu

2016-01-01

Deforestation Profile Sumatera Islands is an island with the highest deforestation rate in Indonesia for the of period 1990???2010, even in Southeast Asia. Deforestation assessment based solely on value of deforestation rate. Deforestation rate was not able to be explained and distinguished at areas that still covering a lot of forest, even at areas that less or no forest. The lowest rate results or zero (0) will be significantly better or assessed as undeforested area. This study was deve...

Extracellular polysaccharidases synthesized by the epiphytic lichen Evernia prunastri (L.) Ach.

Science.gov (United States)

Yagüe, E; Orus, M I; Estevez, M P

1984-03-01

Evernia prunastri Ach., an epiphytic lichen growing on Quercus rotundifolia Lam., produces a β-1,4-glucanase (EC 3.2.1.4) and a polygalacturonase (EC 3.2.1.15). The activity of these polysaccharidases increases as a response to incubation of the lichen with carboxymethylcellulose or sodium polygalacturonate, respectively. This increase in activity is thought to be the result of enzyme induction because it is inhibited by both cycloheximide and 8-azaguanine. Both polysaccharide-degrading enzymes are partially secreted into the incubation media.

Aging of oxygen and hydrogen plasma discharge treated a-C:H and ta-C coatings

Science.gov (United States)

Bachmann, Svenja; Schulze, Marcus; Morasch, Jan; Hesse, Sabine; Hussein, Laith; Krell, Lisa; Schnagl, Johann; Stark, Robert W.; Narayan, Suman

2016-05-01

Surface modification with gas plasma is an efficient and easy way to improve the surface energy and the tribological behavior of diamond-like carbon (DLC) coatings, e.g., in biomedical implants or as protective coatings. However, the long-term performance of the plasma treated DLC coatings is not fully clear. We thus studied the long-term stability of two kinds of DLC coatings, namely (a) hydrogenated amorphous carbon (a-C:H) and (b) tetrahedral amorphous carbon (ta-C) treated at different radio frequency (RF) power and time of oxygen (O2) and hydrogen (H2) plasma. Their surface properties, e.g. surface wettability, structure and tribological behavior, were studied at regular intervals for a period of two months using contact angle goniometer, Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), lateral force microscopy (LFM) and ball on disc apparatus. The surface energy of both the coatings decreased upon aging. The higher the RF power and time of treatment, the higher was the hydrophobicity upon aging. XPS analysis showed that the increase in hydrophobicity could be due to adsorption of unavoidable volatile organic components in the atmosphere. The H2 plasma treated ta-C was capable of rearranging its structural bonds upon aging. The nano-friction measurements by LFM showed that the coefficient of friction of plasma treated a-C:H and ta-C decreased upon aging. The results indicate that the surface properties of plasma treated a-C:H and ta-C are not stable on long-term and are influenced by the environmental conditions.

Children’s use of Bahasa Indonesia in Jakarta kindergartens

NARCIS (Netherlands)

Everaert, M.B.H.; Van de Velde, H.; Kushartanti, B.

2015-01-01

At a very young age children living in Jakarta use both Colloquial Jakarta Indonesia and Bahasa Indonesia. The children’s first and most used language is Colloquial Jakarta Indonesia. In the formal school setting Bahasa Indonesia is frequently used and stimulated on a daily basis, and the learning

UPAYA PENANGGULANGAN TINDAK PIDANA TERORISME di Indonesia

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Hery Firmansyah

2011-06-01

Full Text Available Terrorism has become the most serious issue in Indonesia after terrorist attacks in Bali, November 2002. With the current condition where Indonesia still faces a key risk of new militant attacks with new cells and more bomb experts, this paper aims to analyse the way Indonesian government fight against terrorism. Terorisme adalah permasalahan yang sangat serius di Indonesia, pasca serangan bom di Bali pada November 2002. Dengan keadaan sekarang di mana Indonesia masih menghadapi permasalahan serius serangan militan dengan jaringan baru dan lebih banyak ahli bom, tulisan ini bertujuan menganalisis cara yang ditempuh pemerintah untuk melakukan penanggulangan tindak pidana terorisme.

Penanggulangan Bencana Sebagai Soft Power Dalam Diplomasi Indonesia

OpenAIRE

Herningtyas, Ratih

2014-01-01

This paper aims to describe how the issue of disasters in Indonesia can be modified into a positive social capital to solve social, economic, political and social culture's problems in disaster prone areas. This paper found that Indonesia's disaster managements get worldwide recognition and increases Indonesia's competitiveness toward other countries. These recognitions become the sources of Indonesia's soft power, and can be used as a strategic instrument to build regional cooperation and In...

KEJAHATAN KORPORASI DALAM HUKUM PERBANKAN INDONESIA

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Theodosiva Yovita

2005-04-01

Full Text Available Subjects involved in criminal law are people and corporation. In banking crime when a corporate involved the law enforcement is frequently less cared about. Therefore, it will be a need to do further study on how a banking law regulates the corporation crime in Indonesia. Corporation in Banking Law has a broader meaning than in Civil Law A form of corporation crime is raising fund from the community without any license from Central Bank of Indonesia, Bank Indonesia.

Strengthening Indonesia's health workforce through partnerships.

Science.gov (United States)

Kurniati, A; Rosskam, E; Afzal, M M; Suryowinoto, T B; Mukti, A G

2015-09-01

Indonesia faces critical challenges pertaining to human resources for health (HRH). These relate to HRH policy, planning, mismatch between production and demand, quality, renumeration, and mal-distribution. This paper provides a state of the art review of the existing conditions in Indonesia, innovations to tackle the problems, results of the innovations to date, and a picture of the on-going challenges that have yet to be met. Reversing this crisis level shortage of HRH requires an inclusive approach to address the underlying challenges. In 2010 the government initiated multi-stakeholder coordination for HRH, using the Country Coordination and Facilitation approach. The process requires committed engagement and coordination of relevant stakeholders to address priority health needs. This manuscript is a formative evaluation of the program using documentary study and analysis. Consistent with Indonesia's decentralized health system, since 2011 local governments also started establishing provincial multi-stakeholder committees and working groups for HRH development. Through this multi-stakeholder approach with high level government support and leadership, Indonesia was able to carry out HRH planning by engaging 164 stakeholders. Multi-stakeholder coordination has produced positive results in Indonesia by bringing about a number of innovations in HRH development to achieve UHC, fostered partnerships, attracted international attention, and galvanized multi-stakeholder support in improving the HRH situation. This approach also has facilitated mobilizing technical and financial support from domestic and international partners for HRH development. Applying the multi-stakeholder engagement and coordination process in Indonesia has proved instrumental in advancing the country's work to achieve Universal Health Coverage and the Millennium Development Goals by 2015. Indonesia continues to face an HRH crisis but the collaborative process provides an opportunity to achieve

A Comparison between Model Base Hardconstrain, Bandlimited, and Sparse-Spike Seismic Inversion: New Insights for CBM Reservoir Modelling on Muara Enim Formation, South Sumatra

Science.gov (United States)

Mohamad Noor, Faris; Adipta, Agra

2018-03-01

Coal Bed Methane (CBM) as a newly developed resource in Indonesia is one of the alternatives to relieve Indonesia’s dependencies on conventional energies. Coal resource of Muara Enim Formation is known as one of the prolific reservoirs in South Sumatra Basin. Seismic inversion and well analysis are done to determine the coal seam characteristics of Muara Enim Formation. This research uses three inversion methods, which are: model base hard- constrain, bandlimited, and sparse-spike inversion. Each type of seismic inversion has its own advantages to display the coal seam and its characteristic. Interpretation result from the analysis data shows that the Muara Enim coal seam has 20 (API) gamma ray value, 1 (gr/cc) – 1.4 (gr/cc) from density log, and low AI cutoff value range between 5000-6400 (m/s)*(g/cc). The distribution of coal seam is laterally thinning northwest to southeast. Coal seam is seen biasedly on model base hard constraint inversion and discontinued on band-limited inversion which isn’t similar to the geological model. The appropriate AI inversion is sparse spike inversion which has 0.884757 value from cross plot inversion as the best correlation value among the chosen inversion methods. Sparse Spike inversion its self-has high amplitude as a proper tool to identify coal seam continuity which commonly appears as a thin layer. Cross-sectional sparse spike inversion shows that there are possible new boreholes in CDP 3662-3722, CDP 3586-3622, and CDP 4004-4148 which is seen in seismic data as a thick coal seam.

MEWUJUDKAN NEGARA HUKUM INDONESIA

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Imam Soebechi

2012-11-01

Full Text Available Artikel yang berjudul “Mewujudkan Negara Hukum” ini merupakan studi tentang konsepsi negara hukum Indonesia yang membedakannya dengan konsepsi negara hukum lain. meski mendapat pengaruh dari berbagai pemikiran, tetapi konsepsi negara hukum Indonesia berbeda dengan konsepsi rule of law dan rechtsstaat. Hal tersebut dapat ditelisik dari dasar falsafah, sifat kedaulatan, kekuasaan organ negara, dan hak asasi manusia. Terdapat enam unsur utama negara hukum indonesia, yaitu : 1 Pancasila; 2 supremasi hukum; 3 demokratis; 4 pembatasan dan pemencaran kekuasaan negara; 5 kekuasaan kehakiman yang bebas dan mandiri; 6 perlindungan hak asasi manusia. Dengan penguatan Indonesia sebagai negara hukum yang demokratis berdasarkan Pancasila maka seharusnya segala bentuk tindakan bernegara dan bermasyarakat harus disandarkan pada hukum.   This Article entitled " the State law of Indonesian" is the result of a study on the conception of the characteristic of law states of Indonesian that distinguish the conception of the state laws in other countries. Based on the research results, can be explained even get the effect of various thoughts, but the conception of law state of Indonesian different with conception the rule of law and rechtstaat. This can be searched from basic of philosophy, the nature of sovereignty, the powers of state organs, and human rights. There are six main elements of Indonesian law states, namely: 1 Pancasila; 2 supremacy of law;; 3 democratic 4 restrictions and dispersal of state power; 4 independent judiciary; 6 protection of human rights. the statement of Indonesia as a democratic rule of law based on Pancasila then should all forms of civic and social action must be based on the law.

Revitalisasi bahasa Indonesia dalam konteks kebahasaan

Directory of Open Access Journals (Sweden)

Ni Wayan Sartini

2014-10-01

Full Text Available Bahasa Indonesia today faces many misuse in its daily usage. The language disorder appears on many aspects on language usage, such as excessive and misguided use of foreign languages, violation of the rules of Bahasa Indonesia in media and in public places, the inclusion of regional language structure, use of acronyms arbitrarily, the emergence of slank language and so on. Regarding the language disorder, there is a strong need of revitalization of Bahasa Indonesia in linguistic context. Revitalization means re-positioning Indonesian on its right place and return its existing language rules. Revitalization of Indonesian is expected to overcome language misuse, expected to reduce the chaos or even eliminate them. Using Bahasa Indonesia correctly and appropriately means modelling the right stance to the only official language in this country.

Chinese Foreign Direct Investment in Indonesia

DEFF Research Database (Denmark)

Gammeltoft, Peter; Tarmidi, Lepi T.

2013-01-01

In Indonesia, no systematic study of Chinese FDI has been undertaken to date. This paper contributes to filling this research gap and analyses the current composition as well as the historical evolution of Chinese FDI in Indonesia, relying on a survey conducted in 2008 among Chinese invested...... enterprises supplemented with key informant interviews, available official statistics and secondary data. Considering the evolution of Chinese investments in Indonesia over time, investments have evolved from being individual and isolated projects to acquiring more systemic properties. Chinese companies have...... acquired a broader sectoral presence in Indonesia and Chinese invested companies in, e.g., extractive or manufacturing activities can increasingly rely on complementary Chinese investments in logistics, travel, finance, etc. Where the local development effects are concerned, a picture emerges where Chinese...

Health Information in Indonesian (Bahasa Indonesia)

Science.gov (United States)

... You Are Here: Home → Multiple Languages → Indonesian (Bahasa Indonesia) URL of this page: https://medlineplus.gov/languages/indonesian.html Health Information in Indonesian (Bahasa Indonesia) To use the sharing features on this page, ...

Tenun Dan Penerapannya pada Desain Interior sebagai Warisan Budaya yang Memiliki Nilai Jual yang Tinggi

Directory of Open Access Journals (Sweden)

Grace Hartanti

2011-04-01

Full Text Available Weaving is one of the traditional fabric cultural arts of Indonesia produced in various regions across the archipelago (Sumatra, Kalimantan, Bali, Sulawesi, Lombok, Sumbawa, etc.. Weaving has a significance, historical value, and high technique both in terms of colors, patterns, materials and type of yarn used and each region has the characteristics of each. Weaving as one of high cultural heritage (Heritage is the pride of Indonesia which may reflect national identity. Therefore, weaving both in terms of production engineering, design and the resulting product should be maintained and preserved its existence, and promoted for reuse. One of them in the world of interior design can be used as an aesthetic element to promote local cultural elements (local content of Indonesia. 

Highlight: Forging the new Indonesia-Canada partnership | CRDI ...

International Development Research Centre (IDRC) Digital Library (Canada)

15 avr. 2016 ... Canada's Centre for International Governance Innovation and Indonesia's Centre for Strategic and International Studies organized the Indonesia-Canada Bilateral Forum, Innovation and Change: Forging the New Indonesia-Canada Partnership. IDRC co-sponsored the meeting, held May 26-27, 2015.

Islamic fundamentalism in Indonesia

OpenAIRE

Nagy, Sandra L.

1996-01-01

This is a study of Islamic fundamentalism in Indonesia. Islamic fundamentalism is defined as the return to the foundations and principles of Islam including all movements based on the desire to create a more Islamic society. After describing the practices and beliefs of Islam, this thesis examines the three aspects of universal Islamic fundamentalism: revivalism, resurgence, and radicalism. It analyzes the role of Islam in Indonesia under Dutch colonial rule, an alien Christian imperialist po...

PERSPEKTIF GLOBAL PENYELESAIAN SENGKETA INVESTASI DI INDONESIA

Directory of Open Access Journals (Sweden)

Muhammad Syaifuddin

2011-06-01

Pembentukan UUPM No. 25/2007 adalah konsekwensi yuridis dari ratifikasi Perjanjian WTO. TRIMs, yang bertujuan menciptakan hukum investasi, termasuk hukum penyelesaian sengketa investasi, yang sesuai dengan kehendak investor asing dalam perspektif global, yaitu: pertama, mengandung karakter hukum yang berkepastian, berkeadilan, dan berefisiensi; dan kedua, berlandaskan spirit hukum yang mengarahkan pemerintah dan penanaman modal asing menyelesaikan sengketa investasi melalui arbitrase internasional daripada pengadilan bahkan arbitrase nasional di Indonesia. Krisis lembaga peradilan di Indonesia harus diselesaikan dengan cara membangun sistem hukum peradilan dengan mengacu pada Pancasila sebagai cita hukum investasi Indonesia. Hal tersebut adalah  suatu syarat bagi terbentuknya aturan hukum penyelesaian sengketa investasi yang serasi dalam perspektif global dan lokal (Indonesia.

ANALISIS IMPOR BERAS DI INDONESIA

Directory of Open Access Journals (Sweden)

Ratih Kumala Sari

2014-10-01

Full Text Available Abstrak ___________________________________________________________________ Salah satu kebijakan pemerintah untuk memenuhi kebutuhan beras yaitu dengan menggenjot produksi beras dalam negeri. Namun dengan semakin meningkatnya jumlah penduduk akan meningkatkan permintaan terhadap beras dan upaya peningkatan produktivitas dalam negeri tidak dapat memenuhi kebutuhan beras dalam negeri. Sehingga untuk menutupi kekurangan tersebut pemerintah mengambil keputusan untuk melakukan impor beras dari negara lain. Akan tetapi pada kenyataannya impor beras dilakukan ketika data statistik menunjukkan bahwa Indonesia sedang mengalami surplus beras. Penelitian ini bertujuan untuk mengetahui faktor-faktor apa saja yang mempengaruhi impor beras di Indonesia. Metode analisis yang digunakan adalah analisis regresi linier berganda dengan model Error Correction Model (ECM. Berdasarkan hasil penelitian disimpulkan bahwa secara parsial maupun secara bersama-sama produksi beras, konsumsi beras, harga beras dalam negeri dan nilai tukar rupiah terhadap dollar AS berpengaruh dan signifikan terhadap impor beras di Indonesia. Abstract ___________________________________________________________________ One of the government’s policy to fulfill the need of rice is to boost the domestic production. However, by increasing the population, the demand of rice will also increase and the effort of increasing the domestic productivity cannot supply domestic rice need. So, to cover the shortage the government make decision to import rice from other countries. Yet, in fact importing rice is occurred when the statistical data showed that the supply of rice in Indonesia is surplus. The purpose of this research is necessary to study the factors which influence the import of rice in Indonesia. The analysis method used is multiple linear regression analysis model with Error Correction Model (ECM. Based on the research proven that partially or jointly the production, the consumption, the

Tuning of the microstructure, mechanical and tribological properties of a-C:H films by bias voltage of high frequency unipolar pulse

International Nuclear Information System (INIS)

Wang, Jia; Cao, Zhongyue; Pan, Fuping; Wang, Fuguo; Liang, Aimin; Zhang, Junyan

2015-01-01

Highlights: • a-C:H films deposited by high frequency unipolar pulse PECVD. • The film structures can be adjusted by bias voltage. • More graphitic structures form at high bias voltage. • The mechanical and tribological properties are improved by these structures. - Abstract: Amorphous hydrogenated carbon (a-C:H) films were prepared by high frequency unipolar pulse plasma-enhanced chemical vapor deposition in CH 4 , Ar, and H 2 atmosphere with the bias voltage in the range of −800 –−1600 V. The microstructures and mechanical properties of a-C:H films were investigated via high resolution transmission electron microscope (HRTEM), Raman spectroscopy, and Nanoindenter. The results reveal that the curved and straight graphitic microstructures appear in amorphous carbon matrix, and their contents increase obviously with the bias voltage. At the same time, the corresponding hardness decreases and elastic recovery increases, however even in such a case films still possess excellent mechanical properties. According to the tribological property characterization, we believe that the bias voltage also influences their tribological performances significantly, the higher the bias voltage finally gets, the lower the friction coefficient and wear rate occur. These results indicate that the microstructures of a-C:H films can be tuned efficiently by bias voltage and the films with good mechanical and tribological properties can be obtained at a higher range.

Tuning of the microstructure, mechanical and tribological properties of a-C:H films by bias voltage of high frequency unipolar pulse

Energy Technology Data Exchange (ETDEWEB)

Wang, Jia; Cao, Zhongyue; Pan, Fuping [State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Wang, Fuguo, E-mail: fgwang@licp.cas.cn [State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Liang, Aimin [State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Zhang, Junyan, E-mail: zhangjunyan@licp.cas.cn [State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000 (China)

2015-11-30

Highlights: • a-C:H films deposited by high frequency unipolar pulse PECVD. • The film structures can be adjusted by bias voltage. • More graphitic structures form at high bias voltage. • The mechanical and tribological properties are improved by these structures. - Abstract: Amorphous hydrogenated carbon (a-C:H) films were prepared by high frequency unipolar pulse plasma-enhanced chemical vapor deposition in CH{sub 4}, Ar, and H{sub 2} atmosphere with the bias voltage in the range of −800 –−1600 V. The microstructures and mechanical properties of a-C:H films were investigated via high resolution transmission electron microscope (HRTEM), Raman spectroscopy, and Nanoindenter. The results reveal that the curved and straight graphitic microstructures appear in amorphous carbon matrix, and their contents increase obviously with the bias voltage. At the same time, the corresponding hardness decreases and elastic recovery increases, however even in such a case films still possess excellent mechanical properties. According to the tribological property characterization, we believe that the bias voltage also influences their tribological performances significantly, the higher the bias voltage finally gets, the lower the friction coefficient and wear rate occur. These results indicate that the microstructures of a-C:H films can be tuned efficiently by bias voltage and the films with good mechanical and tribological properties can be obtained at a higher range.

Activation of α7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-α Production.

Science.gov (United States)

Dong, Miao-Wu; Li, Ming; Chen, Jie; Fu, Tong-Tong; Lin, Ke-Zhi; Ye, Guang-Hua; Han, Jun-Ge; Feng, Xiang-Ping; Li, Xing-Biao; Yu, Lin-Sheng; Fan, Yan-Yan

2016-04-01

Diabetes frequently presents accumulation of advanced glycation end products (AGEs), which might induce excessive TNF-α production from macrophages to cause impaired wound healing. Recent studies have shown that activation of α7 nicotinic acetylcholine receptor (α7nAChR) on macrophages efficiently suppressed TNF-α synthesis. The aim of this study was to investigate the accumulation of AGEs in the wounds and determine whether PNU282987, an α7nAChR agonist, can improve wound repair by inhibiting AGE-mediated TNF-α production in a streptozotocin (STZ)-induced diabetic mouse model. Animals were assigned into four groups: wounded control group, wounded diabetic group, wounded diabetic group treated intraperitoneally with PNU282987, or wounded diabetic group treated intraperitoneally with vehicle. Compared with the non-diabetic control mice, the diabetic mice exhibited delayed wound healing that was characterized by elevated accumulation of AGEs, increased TNF-α level and macrophage infiltration, and decreased fibroblast number and collagen deposition at the late stage of repair. Besides, macrophages of diabetic wounds showed expression of α7nAChR. During late repair, PNU282987 treatment of diabetic mice significantly reduced the level of TNF-α, accelerated wound healing, and elevated fibroblast number and collagen deposition. To investigate the cellular mechanism of these observations, RAW 264.7 cells, a macrophage cell line, were incubated with AGEs in the presence or absence of PNU282987. TNF-α production from AGE-stimulated macrophages was significantly decreased by PNU282987 in a dose-dependent manner. Furthermore, PNU282987 significantly inhibited AGE-induced nuclear factor-κB (NF-κB) activation and receptor for AGE (RAGE) expression. These results strongly suggest that activating α7nAChR can promote diabetic wound healing by suppressing AGE-induced TNF-α production, which may be closely associated with the blockage of NF-κB activation in macrophages.

POLITIK HUKUM PERBANKAN SYARIAH DI INDONESIA

Directory of Open Access Journals (Sweden)

Muhammad Ramadhan

2016-11-01

Full Text Available Abstrak: Politik hukum merupakan sesuatu yang mendasari kebijakan dasar diundangkannya suatu regulasi, dan dasar kebijakan diberlakukannya suatu regulasi tertentu dalam tatanan sistem hukum nasional. Pengaturan dan keberlakuan regulasi perbankan syariah di Indonesia dalam perspektif politik hukum adalah sesuatu yang patut untuk dipahami. Penelitian ini menggunakan metode penelitian kualitatif dengan komparatif deskriptif sebagai analisis berpikirnya. Penelitian ini menunjukkan bahwa regulasi perbankan syariah menjadi cerminan dalam dimensi kebijakan dasar (basic policy. Regulasi perbankan syariah merupakan respons atas perkembangan industri perbankan syariah yang membutuhkan jaminan kepastian hukum dan keadilan hukum dalam suatu regulasi yang jelas. Dalam dimensi kebijakan keberlakuan hukum (enactment policy regulasi perbankan syariah diyakini memberikan manfaat (utility dan kemaslahatan bagi masyarakat Indonesia dan dipandang sejalan dengan tujuan ekonomi nasional. Eksistensi regulasi perbankan syariah di Indonesia saat ini memperkuat teori positivisasi hukum Islam dan memperkuat paradigma hukum profetik dalam sistem hukum nasional. Abstract: Legal Policy of Islamic Banking in Indonesia. Legal policy is something that underlies basic policy of a regulation and a basic policy of enactment specific regulation in the national legal system order. Setting and enforceability of Islamic banking regulations in Indonesia on political law perspective is something that deserves to be understood. This study uses qualitative research with descriptive comparative as its thinking analysis. This study shows that the regulation of Islamic banking was a reflection of basic policy dimension. Islamic banking regulation was a response to growing Islamic banking industry that need of legaly and legal justice in a clear regulation. In the enactment of policy dimension, regulation of Islamic banking is believed to provide utility and benefit for Indonesia people and

INTER-BANK CALL MONEY MARKET TRANSACTION IN INDONESIA

Directory of Open Access Journals (Sweden)

Aries Haryadi

2013-10-01

Full Text Available AbstractThis study analyzes the effect of Indonesian Bank loan, the amount of demand deposits, and the Indonesia economic crisis in 1997 on the interbank call money market transactions in Indonesia using a multiple linear regression method. This study finds that the variables influencing the interbank call money market transactions are the interest rate of interbank call money market and the check money. Both variables have positive effect on the interbank money market transactions in Indonesia.Keywords: Loans, Interest Rate, Check Money, Monetary Crisis, Interbank Money Market TransactionsJEL Classification Numbers: G21, G28AbstrakPenelitian ini menganalisis pengaruh pinjaman Bank Indonesia terhadap tingkat bunga pasar uang antar bank, jumlah uang giral, dan krisis ekonomi Indonesia tahun 1997 terhadap transaksi pasar uang antar bank di Indonesia menggunakan metode regresi linier berganda. Penelitian ini menemukan bahwa variabel yang berpengaruh terhadap transaksi pasar uang antar bank tersebut adalah tingkat bunga pasar uang antar bank dan jumlah uang giral. Dua variabel tersebut berpengaruh positif terhadap transaksi pasar uang antar bank di Indonesia.Keywords: Pinjaman, Tingkat Bunga, Uang Giral, Krisis Moneter, Transaksi Pasar Uang antar BankJEL Classification Numbers: G21, G28

Peasant women and access to land : customary law, state law and gender-based ideology : the case of the Toba-Batak (North Sumatra)

NARCIS (Netherlands)

Simbolon, I.J.

1998-01-01

This study is about opportunities, constraints and strategies regarding access to land of peasant women who live in the changing Toba-Batak patrilineal community of North Sumatra. Their access to land is seen in the wider context of the ongoing pressure of land scarcity due to

KORUPSI DI INDONESIA DALAM PERSPEKTIF HUKUM PIDANA ISLAM

OpenAIRE

Fazzan Fazzan

2015-01-01

Corruption is a crucial problem in Indonesia that could not be resolved yet. Corruption takes place nearly in all aspect of life and makes Indonesia become a foremost country in corruption. In fact, the majority of Indonesians are Muslim. This study aims to define the perspective and the concept of corruption according to Islamic law in Indonesia. This study used descriptive-analytic method and normative approach. The result of this study shows that corruption in Indonesia is process of feat...

Ekonomi Politik Pemberitaan Konflik Persepakbolaan Indonesia

Directory of Open Access Journals (Sweden)

Afdal Makkuraga Putra

2017-01-01

Full Text Available Abstract: This study reveals the interests behind football conflicts news in three newspapers in Indonesia: Kompas, Bola, and Seputar Indonesia. The analysis is based on the political economy of media theory developed by Vincent Mosco, Graham Murdock, and Peter Golding. Using critical paradigm with Norman Fairclough’s model of Critical Discourse Analysis (CDA method, the findings show that the conflicts in Indonesian football have been produced as issues that legitimate the strategic position of the football elite power. The media and journalists were drag into the creation or the legitimation of football elite domination. Keywords: critical discourse analysis, football, political economy of media Abstrak: Penelitian ini mengungkap kepentingan di balik pemberitaan konflik persepakbolaan Indonesia di tiga media cetak, yakni Kompas, Bola dan Seputar Indonesia. Analisis didasarkan pada teori ekonomi politik media yang dikembangkan oleh Vincent Mosco, Graham Murdock, dan Peter Golding. Penelitian ini menggunakan paradigma kritis dengan metode Critical Discourse Analysis (CDA model Norman Fairclough. Hasil penelitian menunjukkan bahwa peristiwa konflik persepakbolaan Indonesia diproduksi menjadi isu yang melegitimasi posisi strategis kekuasaan elit persepakbolaan. Media dan wartawan terseret dalam penciptaan atau pengukuhan kekuasaan dominasi elit persepakbolaan tersebut. Kata Kunci: analisis wacana kritis, ekonomi politik media, sepak bola

Analisis Cadangan Devisa Indonesia

Directory of Open Access Journals (Sweden)

Lusia Bunga Uli

2016-09-01

Full Text Available Abstract This study aims to determine the relationship between variables export, import, and exchange rate against Foreign Exchange Reserves in Indonesia. The data used in the empirical study of a sequence of data monthly time of year 2011.01 through 2014.12 from Bank Indonesia and the Central Statistics Agency (BPS. The analysis tool used is Auto Regression Vector Model (VAR. The results of this study indicate that the one-way relationship between the variables of foreign reserves and export. Then one-way relationship between exchange rate and exports. Lastly, there is a two-way relationship between imports and foreign exchange reserves, two-way relationship between exchange rate and foreign exchange reserves, two-way relationship between imports and exports, two-way relationship between the exchange rate and imports. The results also showed foreign exchange reserves are significantly influenced by the movement itself at a probability of 1 %. Export variable negative and not significantly affect the foreign exchange reserves. While imports of positive and not significant to the foreign exchange reserves. Foreign Exchange Reserves Indonesia is positively influenced by the exchange rate and not significant. Keywords: Foreign exchange reserves, exports, imports, exchange rate   Abstrak. Penelitian ini bertujuan untuk mengetahui seberapa keterkaitan antar variabel ekspor, impor, dan nilai tukar rupiah terhadap Cadangan Devisa Indonesia. Data yang digunakan dalam kajian empiris ini merupakan data runtutaan waktu bulanan dari tahun 2011.01 sampai 2014. 12 yang berasal dari Bank Indonesia dan Badan Pusat Statistik (BPS. Alat analisis yang digunakan yaitu Vector Autoregression Model (VAR. Hasil dari penelitian ini menunjukkan bahwa hubungan searah antara variabel cadangan devisa ke ekspor. Lalu hubungan searah antara kurs terhadap ekspor Terakhir, terdapat hubungan dua arah antara impor dan cadangan devisa, hubungan dua arah antara kurs dan cadangan

BOTANICAL EXPLORATION IN THE LAMPUNG PROVINCE, SUMATRA

Directory of Open Access Journals (Sweden)

M. Jacobs

2014-01-01

Full Text Available This is the report of a trip in 1968 conducted by Dr. M. Jacobs of the Rijksherbarium, Leiden, Netherlands, and Dr. B. Prijanto of the Forest Research Institute, Bogor, Indonesia. Financial support was given by the Netherlands Foundation for the Advancement of Tropical Research (WOTRO. Our sincere thanks are due to the liberal way in which this organisation made the enterprise possible, as a continuation of an expedition to the Philippines, on which a report by the same author is now in the press with the journal Blumea.

Phytoplankton blooms induced/sustained by cyclonic eddies during the Indian Ocean Dipole event of 1997 along the southern coasts of Java and Sumatra

Science.gov (United States)

Reddy, P. Rahul Chand; Salvekar, P. S.

2008-09-01

The Indonesian archipelago is the gateway in the tropics connecting two oceans (Pacific and the Indian Ocean) and two continents (Asia and Australia). During the Indian Ocean Dipole 1997, record anomalous and unanticipated upwelling had occurred along the southern coasts of Java and Sumatra causing massive phytoplankton blooms. But the method/mode/process for such anomalous upwelling was not known. Using monthly SeaWifs chlorophyll-a anomalies, TOPEX Sea Surface Height (SSH) anomalies, Sea Surface Temperatures (SST) and currents from a state-of-the-art OGCM, we report the presence of a series of cyclonic eddies along southern coasts of Sumatra and Java during November, December 1997 and January 1998. Upwelling caused by these cyclonic eddies, as also supported by the SSH and SST anomalies, has been responsible for the phytoplankton blooms to persist and dissipate during the 3 months (November, December 1997 and January 1998).

Hubungan Bilateral Indonesia-Malaysia (Studi Analisis: Dampak Ekonomi Dan Politik Dari Pengiriman Tenaga Kerja Indonesia (TKI) Ke Malaysia Periode 2004-2009)

OpenAIRE

Sitorus, Utari Romauli

2014-01-01

This study tries to provide an overview of the phenomena that occur in the process of sending Indonesian Workers (TKI) in Indonesia to Malaysia. The study of the bilateral relations between Indonesia and Malaysia in the process of cooperation in the field of labor is interesting to study because of the mobilization of Indonesian workers have occurred since the 20th century. Unemployment problem that occurred in Indonesia since the 1980s to encourage labor migration from Indonesia to work abro...

Shia: Its History and Development in Indonesia

Directory of Open Access Journals (Sweden)

Moh Hasyim

2012-12-01

Full Text Available Shiah becomes a new problem in Indonesia after hundreds years of living together. Currently, treatment to Shiah tends to violate the principles of religious freedom. Therefore, it is necessary to know, how the history of the emergence of Shiah and its development in Indonesia? This is a library research using a critical analysis approach. This study found that the Syiah is a religious ideology which refers to the views of Saidina Ali (the fourth khalifat and his descendants. This teaching emerged since the beginning of the khulafaurasidin. Shiah has developed dozens of religiousstreams due to disagreement and differences on the idea of Imamah. There are four stages of Shiah development in Indonesia, namely: Firstly, along with the arrival of Islam in Indonesia; Secondly, after the Islamic revolution in Iran; Thirdly, through Indonesian Muslim Intellectuals who studied in Iran, and Finally,  during the open era there was an establishment of as association Jamaah Ahlul Bai’t Indonesia.

KAJIAN KONSISTENSI SIKAP DAN PERBUATAN BERBAHASA INDONESIA BIDANG KEILMUAN

Directory of Open Access Journals (Sweden)

Marsudi Marsudi

2017-11-01

Full Text Available Attitude can be defined as permanent sense, thought, and preference on specific aspect of life. In fact, language attitude of speakers of Bahasa Indonesia is interesting to be questioned. In relation to this, the aim of this research is to describe consistency in terms of language attitude and language performance among Bahasa Indonesia users. Positive thought and sense toward Bahasa Indonesia should be completely or at least partly actualized on the use of standard language when it is implemented in academic setting. Cases found in the use of Bahasa Indonesia tend to oppose the essence of language attitude Inconsistency among bahasa Indonesia attitude lies on the level of spelling, diction, and sentence structures The causes of this inconsistency rest on the disparage and ignorance of Bahasa Indonesia language principles The use of Bahasa Indonesia ignoring language principles particularly on academic setting is viewed as unimportant and unurgent matter. Therefore, negative attitude emerges as a result of ignored language principles.

Contemporary United States Foreign Policy Towards Indonesia

National Research Council Canada - National Science Library

McAslan, Hugh

2004-01-01

United States national interests in Indonesia have traditionally being based on strategic security requirements given Indonesia's geographic location between the Indian and Pacific Oceans, and strong...

EMME (Indonesia)

Data.gov (United States)

US Agency for International Development — EMME is a program specific M&E tool for the Indonesia Mission that is managed by RTI and provides access to project statuses and success stories for the USAID...

Implementasi Perjanjian Kemitraan Ekonomi Indonesia-Jepang: Analisis dari Perspektif Indonesia

Directory of Open Access Journals (Sweden)

Syamsul Hadi

2014-12-01

Full Text Available This article describes the implementation of Indonesia-Japan Economic Partnership (IJEPA in four main sectors: trade, investment, manpower, and capacity building from the Indonesian perspective. It finds that in its implementation, IJEPA suffers some obstacles that hampers Indonesia’s expectation, especially in manpower and capacity building cooperation. In trade, Japan’s tariff reduction under the IJEPA does not necessarily lead to Indonesia’s automatic market penetration to Japanese market as the actual obstacle is not on tariff barriers, but non-tariff barriers. Exception could be seen in investment sector, which has shown a relatively good progress, especially on Japanese increasing interests as well as its actual investment in various sectors in Indonesia.

Entering the nuclear debate in Indonesia

International Nuclear Information System (INIS)

Schlapfer, A.; Marinova, D.

1995-01-01

The authors discuss the risks involved with nuclear technology in relation to the specific geographic, economic and political situation of Indonesia, and argue that Australia must demonstrate a strong interest in any energy decision made in Indonesia. 11 refs., 1 tab., 1 fig

Pirenzepine block of ACh-induced mucus secretion in tracheal submucosal gland cells

International Nuclear Information System (INIS)

Farley, J.M.; Dwyer, T.M.

1991-01-01

Muscarinic stimulation of mucus secretion, as measured by the release of [ 3 H]glycoprotein, was studied in explants from the tracheal epithelium of weanling swine. The mucus glycoprotein secretion was transient, ceasing within the first 10 min of a continuous exposure to 100 μM ACh. Increasing the solutions' osmotic pressure did not alter basal mucus glycoprotein secretion. Mucus glycoprotein secretion was inhibited by 2-10 μM PZP, indicting that the M 3 muscarinic receptors mediate cholinergic stimulation of mucus production