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Sample records for accumulated dose measurement

  1. Dynamically accumulated dose and 4D accumulated dose for moving tumors

    International Nuclear Information System (INIS)

    Li Heng; Li Yupeng; Zhang Xiaodong; Li Xiaoqiang; Liu Wei; Gillin, Michael T.; Zhu, X. Ronald

    2012-01-01

    Purpose: The purpose of this work was to investigate the relationship between dynamically accumulated dose (dynamic dose) and 4D accumulated dose (4D dose) for irradiation of moving tumors, and to quantify the dose uncertainty induced by tumor motion. Methods: The authors established that regardless of treatment modality and delivery properties, the dynamic dose will converge to the 4D dose, instead of the 3D static dose, after multiple deliveries. The bounds of dynamic dose, or the maximum estimation error using 4D or static dose, were established for the 4D and static doses, respectively. Numerical simulations were performed (1) to prove the principle that for each phase, after multiple deliveries, the average number of deliveries for any given time converges to the total number of fractions (K) over the number of phases (N); (2) to investigate the dose difference between the 4D and dynamic doses as a function of the number of deliveries for deliveries of a “pulsed beam”; and (3) to investigate the dose difference between 4D dose and dynamic doses as a function of delivery time for deliveries of a “continuous beam.” A Poisson model was developed to estimate the mean dose error as a function of number of deliveries or delivered time for both pulsed beam and continuous beam. Results: The numerical simulations confirmed that the number of deliveries for each phase converges to K/N, assuming a random starting phase. Simulations for the pulsed beam and continuous beam also suggested that the dose error is a strong function of the number of deliveries and/or total deliver time and could be a function of the breathing cycle, depending on the mode of delivery. The Poisson model agrees well with the simulation. Conclusions: Dynamically accumulated dose will converge to the 4D accumulated dose after multiple deliveries, regardless of treatment modality. Bounds of the dynamic dose could be determined using quantities derived from 4D doses, and the mean dose

  2. Multiple anatomy optimization of accumulated dose

    International Nuclear Information System (INIS)

    Watkins, W. Tyler; Siebers, Jeffrey V.; Moore, Joseph A.; Gordon, James; Hugo, Geoffrey D.

    2014-01-01

    Purpose: To investigate the potential advantages of multiple anatomy optimization (MAO) for lung cancer radiation therapy compared to the internal target volume (ITV) approach. Methods: MAO aims to optimize a single fluence to be delivered under free-breathing conditions such that the accumulated dose meets the plan objectives, where accumulated dose is defined as the sum of deformably mapped doses computed on each phase of a single four dimensional computed tomography (4DCT) dataset. Phantom and patient simulation studies were carried out to investigate potential advantages of MAO compared to ITV planning. Through simulated delivery of the ITV- and MAO-plans, target dose variations were also investigated. Results: By optimizing the accumulated dose, MAO shows the potential to ensure dose to the moving target meets plan objectives while simultaneously reducing dose to organs at risk (OARs) compared with ITV planning. While consistently superior to the ITV approach, MAO resulted in equivalent OAR dosimetry at planning objective dose levels to within 2% volume in 14/30 plans and to within 3% volume in 19/30 plans for each lung V20, esophagus V25, and heart V30. Despite large variations in per-fraction respiratory phase weights in simulated deliveries at high dose rates (e.g., treating 4/10 phases during single fraction beams) the cumulative clinical target volume (CTV) dose after 30 fractions and per-fraction dose were constant independent of planning technique. In one case considered, however, per-phase CTV dose varied from 74% to 117% of prescription implying the level of ITV-dose heterogeneity may not be appropriate with conventional, free-breathing delivery. Conclusions: MAO incorporates 4DCT information in an optimized dose distribution and can achieve a superior plan in terms of accumulated dose to the moving target and OAR sparing compared to ITV-plans. An appropriate level of dose heterogeneity in MAO plans must be further investigated

  3. Multiple anatomy optimization of accumulated dose

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    Watkins, W. Tyler, E-mail: watkinswt@virginia.edu; Siebers, Jeffrey V. [Department of Radiation Oncology, University of Virginia, Charlottesville, Virginia 22908 and Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia 23298 (United States); Moore, Joseph A. [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland 21231 and Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia 23298 (United States); Gordon, James [Henry Ford Health System, Detroit, Michigan 48202 and Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia 23298 (United States); Hugo, Geoffrey D. [Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia 23298 (United States)

    2014-11-01

    Purpose: To investigate the potential advantages of multiple anatomy optimization (MAO) for lung cancer radiation therapy compared to the internal target volume (ITV) approach. Methods: MAO aims to optimize a single fluence to be delivered under free-breathing conditions such that the accumulated dose meets the plan objectives, where accumulated dose is defined as the sum of deformably mapped doses computed on each phase of a single four dimensional computed tomography (4DCT) dataset. Phantom and patient simulation studies were carried out to investigate potential advantages of MAO compared to ITV planning. Through simulated delivery of the ITV- and MAO-plans, target dose variations were also investigated. Results: By optimizing the accumulated dose, MAO shows the potential to ensure dose to the moving target meets plan objectives while simultaneously reducing dose to organs at risk (OARs) compared with ITV planning. While consistently superior to the ITV approach, MAO resulted in equivalent OAR dosimetry at planning objective dose levels to within 2% volume in 14/30 plans and to within 3% volume in 19/30 plans for each lung V20, esophagus V25, and heart V30. Despite large variations in per-fraction respiratory phase weights in simulated deliveries at high dose rates (e.g., treating 4/10 phases during single fraction beams) the cumulative clinical target volume (CTV) dose after 30 fractions and per-fraction dose were constant independent of planning technique. In one case considered, however, per-phase CTV dose varied from 74% to 117% of prescription implying the level of ITV-dose heterogeneity may not be appropriate with conventional, free-breathing delivery. Conclusions: MAO incorporates 4DCT information in an optimized dose distribution and can achieve a superior plan in terms of accumulated dose to the moving target and OAR sparing compared to ITV-plans. An appropriate level of dose heterogeneity in MAO plans must be further investigated.

  4. Multiple anatomy optimization of accumulated dose.

    Science.gov (United States)

    Watkins, W Tyler; Moore, Joseph A; Gordon, James; Hugo, Geoffrey D; Siebers, Jeffrey V

    2014-11-01

    To investigate the potential advantages of multiple anatomy optimization (MAO) for lung cancer radiation therapy compared to the internal target volume (ITV) approach. MAO aims to optimize a single fluence to be delivered under free-breathing conditions such that the accumulated dose meets the plan objectives, where accumulated dose is defined as the sum of deformably mapped doses computed on each phase of a single four dimensional computed tomography (4DCT) dataset. Phantom and patient simulation studies were carried out to investigate potential advantages of MAO compared to ITV planning. Through simulated delivery of the ITV- and MAO-plans, target dose variations were also investigated. By optimizing the accumulated dose, MAO shows the potential to ensure dose to the moving target meets plan objectives while simultaneously reducing dose to organs at risk (OARs) compared with ITV planning. While consistently superior to the ITV approach, MAO resulted in equivalent OAR dosimetry at planning objective dose levels to within 2% volume in 14/30 plans and to within 3% volume in 19/30 plans for each lung V20, esophagus V25, and heart V30. Despite large variations in per-fraction respiratory phase weights in simulated deliveries at high dose rates (e.g., treating 4/10 phases during single fraction beams) the cumulative clinical target volume (CTV) dose after 30 fractions and per-fraction dose were constant independent of planning technique. In one case considered, however, per-phase CTV dose varied from 74% to 117% of prescription implying the level of ITV-dose heterogeneity may not be appropriate with conventional, free-breathing delivery. MAO incorporates 4DCT information in an optimized dose distribution and can achieve a superior plan in terms of accumulated dose to the moving target and OAR sparing compared to ITV-plans. An appropriate level of dose heterogeneity in MAO plans must be further investigated.

  5. Development of a deformable dosimetric phantom to verify dose accumulation algorithms for adaptive radiotherapy.

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    Zhong, Hualiang; Adams, Jeffrey; Glide-Hurst, Carri; Zhang, Hualin; Li, Haisen; Chetty, Indrin J

    2016-01-01

    Adaptive radiotherapy may improve treatment outcomes for lung cancer patients. Because of the lack of an effective tool for quality assurance, this therapeutic modality is not yet accepted in clinic. The purpose of this study is to develop a deformable physical phantom for validation of dose accumulation algorithms in regions with heterogeneous mass. A three-dimensional (3D) deformable phantom was developed containing a tissue-equivalent tumor and heterogeneous sponge inserts. Thermoluminescent dosimeters (TLDs) were placed at multiple locations in the phantom each time before dose measurement. Doses were measured with the phantom in both the static and deformed cases. The deformation of the phantom was actuated by a motor driven piston. 4D computed tomography images were acquired to calculate 3D doses at each phase using Pinnacle and EGSnrc/DOSXYZnrc. These images were registered using two registration software packages: VelocityAI and Elastix. With the resultant displacement vector fields (DVFs), the calculated 3D doses were accumulated using a mass-and energy congruent mapping method and compared to those measured by the TLDs at four typical locations. In the static case, TLD measurements agreed with all the algorithms by 1.8% at the center of the tumor volume and by 4.0% in the penumbra. In the deformable case, the phantom's deformation was reproduced within 1.1 mm. For the 3D dose calculated by Pinnacle, the total dose accumulated with the Elastix DVF agreed well to the TLD measurements with their differences <2.5% at four measured locations. When the VelocityAI DVF was used, their difference increased up to 11.8%. For the 3D dose calculated by EGSnrc/DOSXYZnrc, the total doses accumulated with the two DVFs were within 5.7% of the TLD measurements which are slightly over the rate of 5% for clinical acceptance. The detector-embedded deformable phantom allows radiation dose to be measured in a dynamic environment, similar to deforming lung tissues, supporting

  6. Development of a deformable dosimetric phantom to verify dose accumulation algorithms for adaptive radiotherapy

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    Hualiang Zhong

    2016-01-01

    Full Text Available Adaptive radiotherapy may improve treatment outcomes for lung cancer patients. Because of the lack of an effective tool for quality assurance, this therapeutic modality is not yet accepted in clinic. The purpose of this study is to develop a deformable physical phantom for validation of dose accumulation algorithms in regions with heterogeneous mass. A three-dimensional (3D deformable phantom was developed containing a tissue-equivalent tumor and heterogeneous sponge inserts. Thermoluminescent dosimeters (TLDs were placed at multiple locations in the phantom each time before dose measurement. Doses were measured with the phantom in both the static and deformed cases. The deformation of the phantom was actuated by a motor driven piston. 4D computed tomography images were acquired to calculate 3D doses at each phase using Pinnacle and EGSnrc/DOSXYZnrc. These images were registered using two registration software packages: VelocityAI and Elastix. With the resultant displacement vector fields (DVFs, the calculated 3D doses were accumulated using a mass-and energy congruent mapping method and compared to those measured by the TLDs at four typical locations. In the static case, TLD measurements agreed with all the algorithms by 1.8% at the center of the tumor volume and by 4.0% in the penumbra. In the deformable case, the phantom's deformation was reproduced within 1.1 mm. For the 3D dose calculated by Pinnacle, the total dose accumulated with the Elastix DVF agreed well to the TLD measurements with their differences <2.5% at four measured locations. When the VelocityAI DVF was used, their difference increased up to 11.8%. For the 3D dose calculated by EGSnrc/DOSXYZnrc, the total doses accumulated with the two DVFs were within 5.7% of the TLD measurements which are slightly over the rate of 5% for clinical acceptance. The detector-embedded deformable phantom allows radiation dose to be measured in a dynamic environment, similar to deforming lung

  7. SU-F-T-474: Evaluation of Dose Perturbation, Temperature and Sensitivity Variation With Accumulated Dose of MOSFET Detector

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    Ganesan, B; Prakasarao, A; Singaravelu, G [Anna University, Chennai, TamilNadu (India); Palraj, T; Rai, R [Dr. Rai Memorial Cancer Institute, Chennai, TamilNadu (India)

    2016-06-15

    Purpose: The use of mega voltage gamma and x-ray sources with their skin sparring qualities in radiation therapy has been a boon in relieving patient discomfort and allowing high tumor doses to be given with fewer restrictions due to radiation effects in the skin. However, high doses given to deep tumors may require careful consideration of dose distribution in the buildup region in order to avoid irreparable damage to the skin. Methods: To measure the perturbation of MOSFET detector in Co60,6MV and 15MV the detector was placed on the surface of the phantom covered with the brass build up cap. To measure the effect of temperature the MOSFET detector was kept on the surface of hot water polythene container and the radiation was delivere. In order to measure the sensitivity variation with accumulated dose Measurements were taken by delivering the dose of 200 cGy to MOSFET until the MOSFET absorbed dose comes to 20,000 cGy Results: the Measurement was performed by positioning the bare MOSFET and MOSFET with brass build up cap on the top surface of the solid water phantom for various field sizes in order to find whether there is any attenuation caused in the dose distribution. The response of MOSFET was monitored for temperature ranging from 42 degree C to 22 degree C. The integrated dose dependence of MOSFET dosimeter sensitivity over different energy is not well characterized. This work investigates the dual-bias MOSFET dosimeter sensitivity response to 6 MV and 15 MV beams. Conclusion: From this study it is observed that unlike diode, bare MOSFET does not perturb the radiation field.. It is observed that the build-up influences the temperature dependency of MOSFET and causes some uncertainty in the readings. In the case of sensitivity variation with accumulated dose MOSFET showed higher sensitivity with dose accumulation for both the energies.

  8. SU-F-T-474: Evaluation of Dose Perturbation, Temperature and Sensitivity Variation With Accumulated Dose of MOSFET Detector

    International Nuclear Information System (INIS)

    Ganesan, B; Prakasarao, A; Singaravelu, G; Palraj, T; Rai, R

    2016-01-01

    Purpose: The use of mega voltage gamma and x-ray sources with their skin sparring qualities in radiation therapy has been a boon in relieving patient discomfort and allowing high tumor doses to be given with fewer restrictions due to radiation effects in the skin. However, high doses given to deep tumors may require careful consideration of dose distribution in the buildup region in order to avoid irreparable damage to the skin. Methods: To measure the perturbation of MOSFET detector in Co60,6MV and 15MV the detector was placed on the surface of the phantom covered with the brass build up cap. To measure the effect of temperature the MOSFET detector was kept on the surface of hot water polythene container and the radiation was delivere. In order to measure the sensitivity variation with accumulated dose Measurements were taken by delivering the dose of 200 cGy to MOSFET until the MOSFET absorbed dose comes to 20,000 cGy Results: the Measurement was performed by positioning the bare MOSFET and MOSFET with brass build up cap on the top surface of the solid water phantom for various field sizes in order to find whether there is any attenuation caused in the dose distribution. The response of MOSFET was monitored for temperature ranging from 42 degree C to 22 degree C. The integrated dose dependence of MOSFET dosimeter sensitivity over different energy is not well characterized. This work investigates the dual-bias MOSFET dosimeter sensitivity response to 6 MV and 15 MV beams. Conclusion: From this study it is observed that unlike diode, bare MOSFET does not perturb the radiation field.. It is observed that the build-up influences the temperature dependency of MOSFET and causes some uncertainty in the readings. In the case of sensitivity variation with accumulated dose MOSFET showed higher sensitivity with dose accumulation for both the energies.

  9. A model to accumulate fractionated dose in a deforming organ

    International Nuclear Information System (INIS)

    Yan Di; Jaffray, D.A.; Wong, J.W.

    1999-01-01

    Purpose: Measurements of internal organ motion have demonstrated that daily organ deformation exists throughout the course of radiation treatment. However, a method of constructing the resultant dose delivered to the organ volume remains a difficult challenge. In this study, a model to quantify internal organ motion and a method to construct a cumulative dose in a deforming organ are introduced. Methods and Materials: A biomechanical model of an elastic body is used to quantify patient organ motion in the process of radiation therapy. Intertreatment displacements of volume elements in an organ of interest is calculated by applying an finite element method with boundary conditions, obtained from multiple daily computed tomography (CT) measurements. Therefore, by incorporating also the measurements of daily setup error, daily dose delivered to a deforming organ can be accumulated by tracking the position of volume elements in the organ. Furthermore, distribution of patient-specific organ motion is also predicted during the early phase of treatment delivery using the daily measurements, and the cumulative dose distribution in the organ can then be estimated. This dose distribution will be updated whenever a new measurement becomes available, and used to reoptimize the ongoing treatment. Results: An integrated process to accumulate dosage in a daily deforming organ was implemented. In this process, intertreatment organ motion and setup error were systematically quantified, and incorporated in the calculation of the cumulative dose. An example of the rectal wall motion in a prostate treatment was applied to test the model. The displacements of volume elements in the rectal wall, as well as the resultant doses, were calculated. Conclusion: This study is intended to provide a systematic framework to incorporate daily patient-specific organ motion and setup error in the reconstruction of the cumulative dose distribution in an organ of interest. The realistic dose

  10. A summary of data on accumulated occupational radiation doses among Canadian workers

    International Nuclear Information System (INIS)

    Sont, W.N.

    1994-01-01

    This paper is based on work done on accumulated career doses. The data are taken from the National Dose Registry and consist of accumulated doses to the monitored workforce from the years 1970, 1975, 1980, 1985, and 1990. Four broad occupational categories are analyzed: medicine, nuclear power, uranium processing (including mining, milling, refining, and fuel fabrication), and industry. Two- and three-dimensional bar charts are used to display workforce sizes, collective accumulated doses, and average accumulated doses over time, broken down by career start. Lognormal plots are used to show the distribution of accumulated doses. Many trends are as could be expected, and some of those may be used for construction of statistical models for career-dose accumulation. The size and accumulated career doses in the workforces of the uranium processing category do not vary regularly with time, and in this case modeling is likely to be difficult. 5 refs., 16 figs., 1 tab

  11. Changes in optically stimulated luminescent dosimeter (OSLD) dosimetric characteristics with accumulated dose

    International Nuclear Information System (INIS)

    Jursinic, Paul A.

    2010-01-01

    Purpose: A new type of in vivo dosimeter, an optically stimulated luminescent dosimeter (OSLD), has now become commercially available for clinical use. The OSLD is a plastic disk infused with aluminum oxide doped with carbon (Al 2 O 3 :C). Crystals of Al 2 O 3 :C, when exposed to ionizing radiation, store energy that is released as luminescence (420 nm) when the OSLD is illuminated with stimulation light (540 nm). The intensity of the luminescence depends on the dose absorbed by the OSLD and the intensity of the stimulation light. The effects of accumulated dose on OSLD response were investigated. Methods: The OSLDs used in this work were nanodot dosimeters, which were read with a MicroStar reader (Landauer, Inc., Glenwood, IL). Dose to the OSLDs was delivered by 6 MV x rays and gamma rays from Co-60 and Ir-192. The signal on the OSLDs after irradiation is removed by optical annealing with a 150 W tungsten-halogen lamp or a 14 W compact fluorescent lamp was investigated. Results: It was found that OSLD response to dose was supralinear and this response was altered with the amount of accumulated dose to the OSLD. The OSLD response can be modeled by a quadratic and an exponential equation. For accumulated doses up to 60 Gy, the OSLD sensitivity (counts/dose) decreases and the extent of supralinear increases. Above 60 Gy of accumulated dose the sensitivity increases and the extent of supralinearity decreases or reaches a plateau, depending on how the OSLDs were optically annealed. With preirradiation of OSLDs with greater than 1 kGy, it is found that the sensitivity reaches a plateau 2.5 folds greater than that of an OSLD with no accumulated dose and the supralinearity disappears. A regeneration of the luminescence signal in the dark after full optical annealing occurs with a half time of about two days. The extent of this regeneration signal depends on the amount of accumulated dose. Conclusions: For in vivo dosimetric measurements, a precision of ±0.5% can be

  12. Study on relations between heavy ions single event upset cross sections and γ accumulated doses

    International Nuclear Information System (INIS)

    He Chaohui; Geng Bin; Wang Yanping; Peng Honglun; Yang Hailiang; Chen Xiaohua; Li Guozheng

    2002-01-01

    Experiments were done under 252 Cf and 60 Co γ source to study the relation between heavy ion Single Event Upset (SEU) cross sections and γ accumulated doses. There was no obvious rule and little influence of γ accumulated doses on SEU cross sections when Static Random Access Memories were in power off mode and static power on mode. In active measuring mode, the SEU cross section increased as the accumulated doses increasing when same data were written in memory cells. If reverse data, such as '55' and 'AA', were written in memory cells during the experiment, the SEU cross sections decreased to the level when memories were not irradiated under 60 Co γ source, even more small. It implied that the influence of γ accumulated doses on SEU cross sections can be set off by this method

  13. SU-F-BRCD-06: Multiple Anatomy Optimization of Accumulated Dose.

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    Watkins, W T; Moore, J A; Sharma, M; Dial, C; Xu, H; Hugo, G D; Gordon, J J; Siebers, J V

    2012-06-01

    Multiple anatomy optimization (MAO) utilizing deformable dose accumulation on entire 4DCT data sets is implemented to overcome ambiguity between optimal dose defined on a single anatomy and optimal accumulated dose resulting from dose delivery to moving and deforming anatomy. Six lung cancer patients are planned using two methods of radiotherapy optimization: the internal target volume (ITV) envelope method and MAO, which simultaneously optimizes a single fluence for delivery to all 10 breathing phases such that the accumulated dose satisfies the plan objectives. Target dose is constrained to 70 Gy. The ITV-plan is optimized on a single breathing phase with the planning target volume defined as the ITV; the MAO target is the moving CTV. MAO is compared to single image ITV optimization based on the accumulated dose assuming equal monitor-units to each phase. Dose-volume differences between single image estimations and 10-image accumulation are examined. Single image optimal dose distributions overestimate target V70 by 4.2%±3.1% (average, one standard deviation) and in five of six cases ipsilateral lung V20 is underestimated (1.4%±0.9%). For these five cases, MAO increases V70 by 2.8%±2.5% (maximum of 6% increase in V70) and reduces ipsilateral lung V20 by up to 3% (average decrease of 1.2%±1.3%). Contralateral lung V20, esophagus V25, and heart V30 are also reduced by up to 5%, 3%, and 3%. For the sixth case, lung tumor motion is on the order of the dose voxel size (3mm), and MAO did not improve upon the ITV plan. Dose-volume optimization on a stationary image does not ensure accumulated dose coverage to the moving CTV. Multiple anatomy optimization can remove dose ambiguity and improve plan quality. P01CA11602 and Philips Medical Systems. © 2012 American Association of Physicists in Medicine.

  14. The effect on dose accumulation accuracy of inverse-consistency and transitivity error reduced deformation maps

    International Nuclear Information System (INIS)

    Hardcastle, Nicholas; Bender, Edward T.; Tomé, Wolfgang A.

    2014-01-01

    It has previously been shown that deformable image registrations (DIRs) often result in deformation maps that are neither inverse-consistent nor transitive, and that the dose accumulation based on these deformation maps can be inconsistent if different image pathways are used for dose accumulation. A method presented to reduce inverse consistency and transitivity errors has been shown to result in more consistent dose accumulation, regardless of the image pathway selected for dose accumulation. The present study investigates the effect on the dose accumulation accuracy of deformation maps processed to reduce inverse consistency and transitivity errors. A set of lung 4DCT phases were analysed, consisting of four images on which a dose grid was created. Dose to 75 corresponding anatomical locations was manually tracked. Dose accumulation was performed between all image sets with Demons derived deformation maps as well as deformation maps processed to reduce inverse consistency and transitivity errors. The ground truth accumulated dose was then compared with the accumulated dose derived from DIR. Two dose accumulation image pathways were considered. The post-processing method to reduce inverse consistency and transitivity errors had minimal effect on the dose accumulation accuracy. There was a statistically significant improvement in dose accumulation accuracy for one pathway, but for the other pathway there was no statistically significant difference. A post-processing technique to reduce inverse consistency and transitivity errors has a positive, yet minimal effect on the dose accumulation accuracy. Thus the post-processing technique improves consistency of dose accumulation with minimal effect on dose accumulation accuracy.

  15. TU-H-CAMPUS-JeP3-02: Automated Dose Accumulation and Dose Accuracy Assessment for Online Or Offline Adaptive Replanning

    International Nuclear Information System (INIS)

    Chen, G; Ahunbay, E; Li, X

    2016-01-01

    Purpose: With introduction of high-quality treatment imaging during radiation therapy (RT) delivery, e.g., MR-Linac, adaptive replanning of either online or offline becomes appealing. Dose accumulation of delivered fractions, a prerequisite for the adaptive replanning, can be cumbersome and inaccurate. The purpose of this work is to develop an automated process to accumulate daily doses and to assess the dose accumulation accuracy voxel-by-voxel for adaptive replanning. Methods: The process includes the following main steps: 1) reconstructing daily dose for each delivered fraction with a treatment planning system (Monaco, Elekta) based on the daily images using machine delivery log file and considering patient repositioning if applicable, 2) overlaying the daily dose to the planning image based on deformable image registering (DIR) (ADMIRE, Elekta), 3) assessing voxel dose deformation accuracy based on deformation field using predetermined criteria, and 4) outputting accumulated dose and dose-accuracy volume histograms and parameters. Daily CTs acquired using a CT-on-rails during routine CT-guided RT for sample patients with head and neck and prostate cancers were used to test the process. Results: Daily and accumulated doses (dose-volume histograms, etc) along with their accuracies (dose-accuracy volume histogram) can be robustly generated using the proposed process. The test data for a head and neck cancer case shows that the gross tumor volume decreased by 20% towards the end of treatment course, and the parotid gland mean dose increased by 10%. Such information would trigger adaptive replanning for the subsequent fractions. The voxel-based accuracy in the accumulated dose showed that errors in accumulated dose near rigid structures were small. Conclusion: A procedure as well as necessary tools to automatically accumulate daily dose and assess dose accumulation accuracy is developed and is useful for adaptive replanning. Partially supported by Elekta, Inc.

  16. Dose rate effects during damage accumulation in silicon

    Energy Technology Data Exchange (ETDEWEB)

    Caturla, M.J.; Diaz de la Rubia, T.

    1997-01-01

    We combine molecular dynamics and Monte Carlo simulations to study damage accumulation and dose rate effects during irradiation of Silicon. We obtain the initial stage of the damage produced by heavy and light ions using classical molecular dynamics simulations. While heavy ions like As or Pt induce amorphization by single ion impact, light ions like B only produce point defects or small clusters of defects. The amorphous pockets generated by heavy ions are stable below room temperature and recrystallize at temperatures below the threshold for recrystallization of a planar amorphous-crystalline interface. The damage accumulation during light ion irradiation is simulated using a Monte Carlo model for defect diffusion. In this approach, we study the damage in the lattice as a function of dose and dose rate. A strong reduction in the total number of defects left in the lattice is observed for lower dose rates.

  17. Dose rate effects during damage accumulation in silicon

    International Nuclear Information System (INIS)

    Caturla, M.J.; Diaz de la Rubia, T.

    1997-01-01

    The authors combine molecular dynamics and Monte Carlo simulations to study damage accumulation and dose rate effects during irradiation of silicon. They obtain the initial stage of the damage produced by heavy and light ions using classical molecular dynamics simulations. While heavy ions like As or Pt induce amorphization by single ion impact, light ions like B only produce point defects or small clusters of defects. The amorphous pockets generated by heavy ions are stable below room temperature and recrystallize at temperatures below the threshold for recrystallization of a planar amorphous-crystalline interface. The damage accumulation during light ion irradiation is simulated using a Monte Carlo model for defect diffusion. In this approach, the authors study the damage in the lattice as a function of dose and dose rate. A strong reduction in the total number of defects left in the lattice is observed for lower dose rates

  18. Accumulated dose calculations in Indian PHWRs under DBA

    International Nuclear Information System (INIS)

    Nesaraj, David; Pradhan, A.S.; Bhardwaj, S.A.

    1996-01-01

    Accumulated gamma dose inside reactor building due to release of fission products from equilibrium core of Indian PHWR under accident condition has been assessed. The assessment has been done for the radiation tolerance limit of the critical equipment inside reactor building. The basic source data has been generated using computer code ORIGEN2 written and developed by Oak Ridge National Laboratory, USA (ORNL). This paper discusses the details of the calculations done on the basis of certain assumption which are mentioned at relevant places. The results indicate accumulated gamma dose at a few typical locations inside reactor building under accident condition. (author). 1 ref., 1 tab., 1 fig

  19. Dose accumulation of multiple high dose rate prostate brachytherapy treatments in two commercially available image registration systems.

    Science.gov (United States)

    Poder, Joel; Yuen, Johnson; Howie, Andrew; Bece, Andrej; Bucci, Joseph

    2017-11-01

    The purpose of this study was to assess whether deformable image registration (DIR) is required for dose accumulation of multiple high dose rate prostate brachytherapy (HDRPBT) plans treated with the same catheter pattern on two different CT datasets. DIR was applied to 20 HDRPBT patients' planning CT images who received two treatment fractions on sequential days, on two different CT datasets, with the same implant. Quality of DIR in Velocity and MIM image registration systems was assessed by calculating the Dice Similarity Coefficient (DSC) and mean distance to agreement (MDA) for the prostate, urethra and rectum contours. Accumulated doses from each system were then calculated using the same DIR technique and dose volume histogram (DVH) parameters compared to manual addition with no DIR. The average DSC was found to be 0.83 (Velocity) and 0.84 (MIM), 0.80 (Velocity) and 0.80 (MIM), 0.80 (Velocity) and 0.81 (MIM), for the prostate, rectum and urethra contours, respectively. The average difference in calculated DVH parameters between the two systems using dose accumulation was less than 1%, and there was no statistically significant difference found between deformably accumulated doses in the two systems versus manual DVH addition with no DIR. Contour propagation using DIR in velocity and MIM was shown to be at least equivalent to inter-observer contouring variability on CT. The results also indicate that dose accumulation through manual addition of DVH parameters may be sufficient for HDRPBT treatments treated with the same catheter pattern on two different CT datasets. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

  20. Nutrient accumulation models in the banana (Musa AAA Simmonds cv Williams plant under nitrogen doses

    Directory of Open Access Journals (Sweden)

    Jaime Torres Bazurto

    2017-07-01

    Full Text Available This research determined the effect of four nitrogen (N doses on the nutritional behavior of (N, potassium (K, phosphorus (P, calcium (Ca and magnesium (Mg, respectively, in banana Williams, during five plant development stages and two productive cycles. The treatments were as follows: 1 absolute control, 2 0 N, 3 161 kg N ha-1, 4 321.8 kg N ha-1 and 5 483 kg N ha-1, respectively. A multivariate approach of the differences among cycles was used to adjust the models and eliminate their individual effect, with a randomized complete block design with repeated measurements over time. There were significant differences among plant development stages, with an increase in nutrient accumulation in the banana plant, there were no differences among treatments or blocks, nor in the interaction block by treatment, but the dose of 321.8 kg of N, exhibited a fructification increase in terms of N accumulation, harvest was exceeded by the dose of 483 kg of nitrogen, Ca and Mg, were the other nutrients, which showed effect at the dose of 483 kg of N but increasing only to harvest. It was concluded that high doses of nitrogen showed a trend to increase nutrient accumulation during the development of the banana plant, but especially until fructification, with the exception of Ca and Mg, which achieved the greatest accumulation in harvest.

  1. Direct dose mapping versus energy/mass transfer mapping for 4D dose accumulation: fundamental differences and dosimetric consequences.

    Science.gov (United States)

    Li, Haisen S; Zhong, Hualiang; Kim, Jinkoo; Glide-Hurst, Carri; Gulam, Misbah; Nurushev, Teamour S; Chetty, Indrin J

    2014-01-06

    The direct dose mapping (DDM) and energy/mass transfer (EMT) mapping are two essential algorithms for accumulating the dose from different anatomic phases to the reference phase when there is organ motion or tumor/tissue deformation during the delivery of radiation therapy. DDM is based on interpolation of the dose values from one dose grid to another and thus lacks rigor in defining the dose when there are multiple dose values mapped to one dose voxel in the reference phase due to tissue/tumor deformation. On the other hand, EMT counts the total energy and mass transferred to each voxel in the reference phase and calculates the dose by dividing the energy by mass. Therefore it is based on fundamentally sound physics principles. In this study, we implemented the two algorithms and integrated them within the Eclipse treatment planning system. We then compared the clinical dosimetric difference between the two algorithms for ten lung cancer patients receiving stereotactic radiosurgery treatment, by accumulating the delivered dose to the end-of-exhale (EE) phase. Specifically, the respiratory period was divided into ten phases and the dose to each phase was calculated and mapped to the EE phase and then accumulated. The displacement vector field generated by Demons-based registration of the source and reference images was used to transfer the dose and energy. The DDM and EMT algorithms produced noticeably different cumulative dose in the regions with sharp mass density variations and/or high dose gradients. For the planning target volume (PTV) and internal target volume (ITV) minimum dose, the difference was up to 11% and 4% respectively. This suggests that DDM might not be adequate for obtaining an accurate dose distribution of the cumulative plan, instead, EMT should be considered.

  2. Three-dimensional dose accumulation in pseudo-split-field IMRT and brachytherapy for locally advanced cervical cancer.

    Science.gov (United States)

    Sun, Baozhou; Yang, Deshan; Esthappan, Jackie; Garcia-Ramirez, Jose; Price, Samantha; Mutic, Sasa; Schwarz, Julie K; Grigsby, Perry W; Tanderup, Kari

    2015-01-01

    Dose accumulation of split-field external beam radiotherapy (EBRT) and brachytherapy (BT) is challenging because of significant EBRT and BT dose gradients in the central pelvic region. We developed a method to determine biologically effective dose parameters for combined split-field intensity-modulated radiation therapy (IMRT) and image-guided BT in locally advanced cervical cancer. Thirty-three patients treated with split-field-IMRT to 45.0-51.2 Gy in 1.6-1.8 Gy per fraction to the elective pelvic lymph nodes and to 20 Gy to the central pelvis region were included in this study. Patients received six weekly fractions of high-dose rate BT to 6.5-7.3 Gy per fraction. A dose tracker software was developed to compute the equivalent dose in 2-Gy fractions (EQD2) to gross tumor volume (GTV), organs-at-risk and point A. Total dose-volume histogram parameters were computed on the 3D combined EQD2 dose based on rigid image registration. The dose accumulation uncertainty introduced by organ deformations between IMRT and BT was evaluated. According to International Commission on Radiation Unit and Measurement and GEC European Society for Therapeutic Radiology and Oncology recommendations, D98, D90, D50, and D2cm3 EQD2 dose-volume histogram parameters were computed. GTV D98 was 84.0 ± 26.5 Gy and D2cc was 99.6 ± 13.9 Gy, 67.4 ± 12.2 Gy, 75.0 ± 10.1 Gy, for bladder, rectum, and sigmoid, respectively. The uncertainties induced by organ deformation were estimated to be -1 ± 4 Gy, -3 ± 5 Gy, 2 ± 3 Gy, and -3 ± 5 Gy for bladder, rectum, sigmoid, and GTV, respectively. It is feasible to perform 3D EQD2 dose accumulation to assess high and intermediate dose regions for combined split-field IMRT and BT. Copyright © 2015 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

  3. Liposome accumulation in irradiated tumors display important tumor and dose dependent differences

    DEFF Research Database (Denmark)

    Hansen, Anders Elias; Fliedner, Frederikke Petrine; Henriksen, Jonas Rosager

    2018-01-01

    Radiation therapy may affect several important parameters in the tumor microenvironment and thereby influence the accumulation of liposomes by the enhanced permeability and retention (EPR)-effect. Here we investigate the effect of single dose radiation therapy on liposome tumor accumulation by PET...

  4. The outcome of adjusted accumulation dose of treatment of Graves' disease

    International Nuclear Information System (INIS)

    Gomi, Yukari; Inoue, Takeshi; Suzuki, Seiji; Hamada, Noboru; Yoshimura, Hiroshi; Ishikawa, Naofumi; Momotani, Naoko; Ito, Kunihiko.

    1997-01-01

    We evaluated the outcome of 131 I treatment of Graves' disease in two different protocols (old and new protocol) of adjusted accumulation dose from 1988 to 1995. Adjusted accumulation doses of patients with above 50 g thyroid weights were increased by 5-20 Gy/g tissue in new protocol compared to those in old one. In 166 patients treated with single and plural doses of 131 I treatment in 1990 (Group In), the therapeutic doses were calculated according to new protocol and in 130 patients in 1988 (Group Io), according to old one, modification of Quimby's formula. The patients treated with plural doses were classified as hyperthyroidism because the efficacies of the first treatments with 131 I were insufficient. At the 5-yr follow up, the incidence of hypothyroid in Group In was 9%, subclinical hypothyroid 17%, euthyroid 30%, subclinical hyperthyroid 7%, hyperthyroid 37%. In Group Io, 11% of the patients were hypothyroid, 6% subclinical hypothyroid, 29% euthyroid, 3% subclinical hyperthyroid, 51% hyperthyroid. The incidence of hyperthyroid in Group In was lower than that in Group Io (p 131 I in relation to the patients' thyroid weight shows some room for improvement. (author)

  5. Effects of Gamma Irradiation and Dose Accumulation on the Histology of Spodoptera littoralis (Boisd.) Male Testes

    International Nuclear Information System (INIS)

    Sallam, H.A.; El-Naggar, S.E.M.; Shibel, M.M.; El-Dossouki, S.A.

    2000-01-01

    Full-grown male pupae of the cotton leaf worm Spodoptera littoralis (Boisd.) were gamma irradiated with low doses of 25, 50, 75 or 100 Gy. The effects of accumulating doses applied to these pupae through three consequent filial generations and the retarded influence on their F 1 , F 2 and F 3 generations progeny were examined. The histological observations showed that the damage in the testes was correlated with increasing the dose applied to the male parents and was the highest among the adults of F 1 . Also, the damage at any acute dose was less than the damage occurred in the same accumulated dose. The deteriorations on the testes were more evident in case of F 1 males resulting from parental males irradiated through two or three successive generations or three accumulated doses of 25 or 50 Gy

  6. Method for assessing the probability of accumulated doses from an intermittent source using the convolution technique

    International Nuclear Information System (INIS)

    Coleman, J.H.

    1980-10-01

    A technique is discussed for computing the probability distribution of the accumulated dose received by an arbitrary receptor resulting from several single releases from an intermittent source. The probability density of the accumulated dose is the convolution of the probability densities of doses from the intermittent releases. Emissions are not assumed to be constant over the brief release period. The fast fourier transform is used in the calculation of the convolution

  7. SU-F-T-329: Characteristic Study of a Rado-Photoluminescenct Glass Dosimeter with Accumulated Dose

    Energy Technology Data Exchange (ETDEWEB)

    Kim, D; Chung, W; Chung, M [Kyung Hee University Hospital at Gangdong, Gangdong-gu (Korea, Republic of); Yoon, M [Korea University, Seoul (Korea, Republic of)

    2016-06-15

    Purpose: This study investigated the effect of accumulated dose on radiophotoluminescent glass dosimeter in megavoltage photon. Methods: 45 commercially-available radio-photoluminescence glass dosimeters (RPLGD; GD-302M, Asahi Techno Glass Co., Shizuoka, JAPAN) were irradiated to 10 × 10 cm{sup 2} open-field with 6, 10 and 15 MV photon beams at 100 cm of source to surface distance and dose maximum depths. Each energy has consists of five groups which is consists of three detectors. A group #1 and #2 was irradiated about 1 Gy to 100 Gy, and estimated the integral dose response with and without annealing procedure. A group #3 was read the dose after irradiated 10 Gy of dose by 10 times repeatedly to estimate the fading effect of RPLGD. A group #4 and #5 was produced same ways with different irradiation dose such as 50 Gy for group #4 and 100 Gy for group #5. Results: From the results of group #1 and #2, an annealed detector shows linear response to integral dose but other detectors without the annealing process, has supra linearity for integral dose especially close to 100 Gy dose. For group #3, #4 and #5, the dose response of repeated irradiation, the dose response was decreased about 15%, 12% and 7% for 6 MV, 10 MV and 15MV. Conclusion: It was found that RPLGD response to accumulated dose was supra linear and this respond was altered with amount of accumulated dose to the RPLGD. In addition, the fading effect need to be concern with RPLGD.

  8. Bladder dose accumulation based on a biomechanical deformable image registration algorithm in volumetric modulated arc therapy for prostate cancer

    International Nuclear Information System (INIS)

    Andersen, E S; Muren, L P; Thor, M; Petersen, J B; Tanderup, K; Sørensen, T S; Noe, K Ø; Høyer, M; Bentzen, L

    2012-01-01

    Variations in bladder position, shape and volume cause uncertainties in the doses delivered to this organ during a course of radiotherapy for pelvic tumors. The purpose of this study was to evaluate the potential of dose accumulation based on repeat imaging and deformable image registration (DIR) to improve the accuracy of bladder dose assessment. For each of nine prostate cancer patients, the initial treatment plan was re-calculated on eight to nine repeat computed tomography (CT) scans. The planned bladder dose–volume histogram (DVH) parameters were compared to corresponding parameters derived from DIR-based accumulations as well as DVH summation based on dose re-calculations. It was found that the deviations between the DIR-based accumulations and the planned treatment were substantial and ranged (−0.5–2.3) Gy and (−9.4–13.5) Gy for D 2% and D mean , respectively, whereas the deviations between DIR-based accumulations and DVH summation were small and well within 1 Gy. For the investigated treatment scenario, DIR-based bladder dose accumulation did not result in substantial improvement of dose estimation as compared to the straightforward DVH summation. Large variations were found in individual patients between the doses from the initial treatment plan and the accumulated bladder doses. Hence, the use of repeat imaging has a potential for improved accuracy in treatment dose reporting. (paper)

  9. Localized accumulation of lead within and among bones from lead-dosed goats

    International Nuclear Information System (INIS)

    Cretacci, Yan; Parsons, Patrick J.

    2010-01-01

    The principal aim of this study was to gain a better understanding of where lead (Pb) accumulates and how it is distributed, within the bones of dosed goats. Adult goats were periodically dosed with Pb over a number of years for the primary purpose of producing blood pools containing endogenously bound Pb, for the New York State Blood Lead Proficiency Testing Program. Bone samples (e.g., primarily tibia, femur, humerus, and radius) were collected post-mortem from 11 animals and were analyzed for Pb content by acid digestion and electrothermal atomic absorption spectrometry (ETAAS or GFAAS). Average tibia Pb levels were found to correlate strongly with the cumulative Pb dose (r 2 =0.81). However, the concentration of Pb in different bones and even within a small area of the same bone varied tremendously. Blood-rich trabecular (spongy) bone, such as the patella and calcaneus, were much more enriched in Pb than was cortical (compact) bone. In some dosed animals, the Pb concentration in the tibia was markedly higher at the proximal and distal ends of the bone compared to the mid-shaft. The implications of these findings with regard to the noninvasive measurement of lead in bone by XRF methods are discussed.

  10. Localized accumulation of lead within and among bones from lead-dosed goats

    Energy Technology Data Exchange (ETDEWEB)

    Cretacci, Yan [Laboratory of Inorganic and Nuclear Chemistry, Wadsworth Center, New York State Department of Health, P.O. Box 509, Albany, NY 12201-0509 (United States); Department of Environmental Health Sciences, School of Public Health, The University at Albany, P.O. Box 509, Albany, NY 12201-0509 (United States); Parsons, Patrick J., E-mail: pparsons@wadsworth.org [Laboratory of Inorganic and Nuclear Chemistry, Wadsworth Center, New York State Department of Health, P.O. Box 509, Albany, NY 12201-0509 (United States); Department of Environmental Health Sciences, School of Public Health, The University at Albany, P.O. Box 509, Albany, NY 12201-0509 (United States)

    2010-01-15

    The principal aim of this study was to gain a better understanding of where lead (Pb) accumulates and how it is distributed, within the bones of dosed goats. Adult goats were periodically dosed with Pb over a number of years for the primary purpose of producing blood pools containing endogenously bound Pb, for the New York State Blood Lead Proficiency Testing Program. Bone samples (e.g., primarily tibia, femur, humerus, and radius) were collected post-mortem from 11 animals and were analyzed for Pb content by acid digestion and electrothermal atomic absorption spectrometry (ETAAS or GFAAS). Average tibia Pb levels were found to correlate strongly with the cumulative Pb dose (r{sup 2}=0.81). However, the concentration of Pb in different bones and even within a small area of the same bone varied tremendously. Blood-rich trabecular (spongy) bone, such as the patella and calcaneus, were much more enriched in Pb than was cortical (compact) bone. In some dosed animals, the Pb concentration in the tibia was markedly higher at the proximal and distal ends of the bone compared to the mid-shaft. The implications of these findings with regard to the noninvasive measurement of lead in bone by XRF methods are discussed.

  11. Characterization of MOSFET dosimeters for low-dose measurements in maxillofacial anthropomorphic phantoms.

    Science.gov (United States)

    Koivisto, Juha H; Wolff, Jan E; Kiljunen, Timo; Schulze, Dirk; Kortesniemi, Mika

    2015-07-08

    The aims of this study were to characterize reinforced metal-oxide-semiconductor field-effect transistor (MOSFET) dosimeters to assess the measurement uncertainty, single exposure low-dose limit with acceptable accuracy, and the number of exposures required to attain the corresponding limit of the thermoluminescent dosimeters (TLD). The second aim was to characterize MOSFET dosimeter sensitivities for two dental photon energy ranges, dose dependency, dose rate dependency, and accumulated dose dependency. A further aim was to compare the performance of MOSFETs with those of TLDs in an anthropomorphic phantom head using a dentomaxillofacial CBCT device. The uncertainty was assessed by exposing 20 MOSFETs and a Barracuda MPD reference dosimeter. The MOSFET dosimeter sensitivities were evaluated for two photon energy ranges (50-90 kVp) using a constant dose and polymethylmethacrylate backscatter material. MOSFET and TLD comparative point-dose measurements were performed on an anthropomorphic phantom that was exposed with a clinical CBCT protocol. The MOSFET single exposure low dose limit (25% uncertainty, k = 2) was 1.69 mGy. An averaging of eight MOSFET exposures was required to attain the corresponding TLD (0.3 mGy) low-dose limit. The sensitivity was 3.09 ± 0.13 mV/mGy independently of the photon energy used. The MOSFET dosimeters did not present dose or dose rate sensitivity but, however, presented a 1% decrease of sensitivity per 1000 mV for accumulated threshold voltages between 8300 mV and 17500 mV. The point doses in an anthropomorphic phantom ranged for MOSFETs between 0.24 mGy and 2.29 mGy and for TLDs between 0.25 and 2.09 mGy, respectively. The mean difference was -8%. The MOSFET dosimeters presented statistically insignificant energy dependency. By averaging multiple exposures, the MOSFET dosimeters can achieve a TLD-comparable low-dose limit and constitute a feasible method for diagnostic dosimetry using anthropomorphic phantoms. However, for single in

  12. Characterization of MOSFET dosimeters for low‐dose measurements in maxillofacial anthropomorphic phantoms

    Science.gov (United States)

    Wolff, Jan E.; Kiljunen, Timo; Schulze, Dirk; Kortesniemi, Mika

    2015-01-01

    The aims of this study were to characterize reinforced metal‐oxide‐semiconductor field‐effect transistor (MOSFET) dosimeters to assess the measurement uncertainty, single exposure low‐dose limit with acceptable accuracy, and the number of exposures required to attain the corresponding limit of the thermoluminescent dosimeters (TLD). The second aim was to characterize MOSFET dosimeter sensitivities for two dental photon energy ranges, dose dependency, dose rate dependency, and accumulated dose dependency. A further aim was to compare the performance of MOSFETs with those of TLDs in an anthropomorphic phantom head using a dentomaxillofacial CBCT device. The uncertainty was assessed by exposing 20 MOSFETs and a Barracuda MPD reference dosimeter. The MOSFET dosimeter sensitivities were evaluated for two photon energy ranges (50–90 kVp) using a constant dose and polymethylmethacrylate backscatter material. MOSFET and TLD comparative point‐dose measurements were performed on an anthropomorphic phantom that was exposed with a clinical CBCT protocol. The MOSFET single exposure low dose limit (25% uncertainty, k=2) was 1.69 mGy. An averaging of eight MOSFET exposures was required to attain the corresponding TLD (0.3 mGy) low‐dose limit. The sensitivity was 3.09±0.13 mV/mGy independently of the photon energy used. The MOSFET dosimeters did not present dose or dose rate sensitivity but, however, presented a 1% decrease of sensitivity per 1000 mV for accumulated threshold voltages between 8300 mV and 17500 mV. The point doses in an anthropomorphic phantom ranged for MOSFETs between 0.24 mGy and 2.29 mGy and for TLDs between 0.25 and 2.09 mGy, respectively. The mean difference was −8%. The MOSFET dosimeters presented statistically insignificant energy dependency. By averaging multiple exposures, the MOSFET dosimeters can achieve a TLD‐comparable low‐dose limit and constitute a feasible method for diagnostic dosimetry using anthropomorphic phantoms. However

  13. Online Radiation Dose Measurement System for ATLAS experiment

    CERN Document Server

    Mandić, I; The ATLAS collaboration

    2012-01-01

    Particle detectors and readout electronics in the high energy physics experiment ATLAS at the Large Hadron Collider at CERN operate in radiation field containing photons, charged particles and neutrons. The particles in the radiation field originate from proton-proton interactions as well as from interactions of these particles with material in the experimental apparatus. In the innermost parts of ATLAS detector components will be exposed to ionizing doses exceeding 100 kGy. Energetic hadrons will also cause displacement damage in silicon equivalent to fluences of several times 10e14 1 MeV-neutrons per cm2. Such radiation doses can have severe influence on the performance of detectors. It is therefore very important to continuously monitor the accumulated doses to understand the detector performance and to correctly predict the lifetime of radiation sensitive components. Measurements of doses are important also to verify the simulations and represent a crucial input into the models used for predicting future ...

  14. Bladder accumulated dose in image-guided high-dose-rate brachytherapy for locally advanced cervical cancer and its relation to urinary toxicity

    Science.gov (United States)

    Zakariaee, Roja; Hamarneh, Ghassan; Brown, Colin J.; Gaudet, Marc; Aquino-Parsons, Christina; Spadinger, Ingrid

    2016-12-01

    The purpose of this study was to estimate locally accumulated dose to the bladder in multi-fraction high-dose-date (HDR) image-guided intracavitary brachytherapy (IG-ICBT) for cervical cancer, and study the locally-accumulated dose parameters as predictors of late urinary toxicity. A retrospective study of 60 cervical cancer patients who received five HDR IG-ICBT sessions was performed. The bladder outer and inner surfaces were segmented for all sessions and a bladder-wall contour point-set was created in MATLAB. The bladder-wall point-sets for each patient were registered using a deformable point-set registration toolbox called coherent point drift (CPD), and the fraction doses were accumulated. Various dosimetric and volumetric parameters were calculated using the registered doses, including r{{\\text{D}}n \\text{c{{\\text{m}}\\text{3}}}} (minimum dose to the most exposed n-cm3 volume of bladder wall), r V n Gy (wall volume receiving at least m Gy), and r\\text{EQD}{{2}n \\text{c{{\\text{m}}\\text{3}}}} (minimum equivalent biologically weighted dose to the most exposed n-cm3 of bladder wall), where n  =  1/2/5/10 and m  =  3/5/10. Minimum dose to contiguous 1 and 2 cm3 hot-spot volumes was also calculated. The unregistered dose volume histogram (DVH)-summed equivalent of r{{\\text{D}}n \\text{c{{\\text{m}}3}}} and r\\text{EQD}{{2}n \\text{c{{\\text{m}}3}}} parameters (i.e. s{{\\text{D}}n \\text{c{{\\text{m}}\\text{3}}}} and s\\text{EQD}{{2}n \\text{c{{\\text{m}}3}}} ) were determined for comparison. Late urinary toxicity was assessed using the LENT-SOMA scale, with toxicity Grade 0-1 categorized as Controls and Grade 2-4 as Cases. A two-sample t-test was used to identify the differences between the means of Control and Case groups for all parameters. A binomial logistic regression was also performed between the registered dose parameters and toxicity grouping. Seventeen patients were in the Case and 43 patients in the Control group. Contiguous

  15. Tritium metabolism in newborn mice and estimation of the accumulated dose

    Energy Technology Data Exchange (ETDEWEB)

    Saito, M; Ishida, M R

    1986-01-01

    Suckling mice received tritium from their mothers who were supplied with tritiated water as drinking water. After weaning, the offspring were sacrificed and the tritium concentration was determined for various organs and various molecular components including acid soluble component, lipid, RNA, DNA and protein. The accumulated dose for the period between 3 and 41 weeks after birth was calculated for various organs and the contributions of the acid insoluble components to the total dose estimated. The per cent contribution of the acid insoluble components to the total dose was organ specific and was between about 17% and 42%. The result indicates that the inhomogeneous distribution of tritium in subcellular structures needs to be taken into account. The contribution of organically bound tritium to dose is then comparable to that of tritium in the free water component.

  16. SU-F-J-99: Dose Accumulation and Evaluation in Lung SBRT Among All Phases of Respiration

    Energy Technology Data Exchange (ETDEWEB)

    Azcona, JD; Barbes, B; Aristu, J; Moreno, M; Zubiria, A [Clinica Universidad de Navarra, Pamplona (Spain); Burguete, J [Universidad de Navarra, Pamplona, Navarra (Spain); Arce, P; Lagares, JI [Centro de Investigaciones Energeticas, Medioambientales, y Tecnologicas, Madrid (Spain)

    2016-06-15

    Purpose: To calculate the total planning dose on lung tumors (GTV) by accumulating the dose received in all respiration phases. Methods: A patient 4D planning CT (phase-binned, from a Siemens Somatom CT) was used to locate the GTV of a lung tumor in all respiratory phases with Pinnacle (v9.10). GTV contours defined in all phases were projected to the reference phase, where the ITV was defined. Centroids were calculated for all the GTV projections. No deformation or rotation was taken into account. The only GTV contour as defined in the reference phase was voxelized to track each voxel individually. We accumulated the absorbed dose in different phases on each voxel. A 3DCRT and a VMAT plan were designed on the reference phase fulfilling the ITV dosimetric requirements, using the 10MV FFF photon model from an Elekta Versa linac. ITV-to-PTV margins were set to 5mm. In-house developed MATLAB code was used for tumor voxeling and dose accumulation, assuming that the dose distribution planned in the reference phase behaved as a “dose-cloud” during patient breathing. Results: We tested the method on a patient 4DCT set of images exhibiting limited tumor motion (<5mm). For the 3DCRT plan, D95 was calculated for the GTV with motion and for the ITV, showing an agreement of 0.04%. For the VMAT plan, we calculated the D95 for every phase as if the GTV in that phase had received the whole treatment. Differences in D95 for all phases are within 1%, and estimate the potential interplay effect during delivery. Conclusion: A method for dose accumulation and assessment was developed that can compare GTV motion with ITV dosage, and estimate the potential interplay effect for VMAT plans. Work in progress includes the incorporation of deformable image registration and 4D CBCT dose calculation for dose reconstruction and assessment during treatment.

  17. Ionization chamber for high dose measurements

    International Nuclear Information System (INIS)

    Rodrigues Junior, Ary de Araujo

    2005-01-01

    Industrial gamma irradiators facilities are designed for processing large amounts of products, which are exposed to large doses of gamma radiation. The irradiation, in industrial scale, is usually carried out in a dynamic form, where the products go through a 60 Co gamma source with activity of TBq to P Bq (k Ci to MCi). The dose is estimated as being directly proportional to the time that the products spend to go through the source. However, in some situations, mainly for research purposes or for validation of customer process following the ISO 11137 requirements, it is required to irradiate small samples in a static position with fractional deliver doses. The samples are put inside the irradiation room at a fixed distance from the source and the dose is usually determined using dosimeters. The dose is only known after the irradiation, by reading the dosimeter. Nevertheless, in the industrial irradiators, usually different kinds of products with different densities go through between the source and the static position samples. So, the dose rate varies in function of the product density. A suitable methodology would be to monitor the samples dose in real time, measuring the dose on line with a radiation detector, which would improve the dose accuracy and avoid the overdose. A cylindrical ionization chamber of 0.9 cm 3 has been developed for high-doses real-time monitoring, during the sample irradiation at a static position in a 60 Co gamma industrial plant. Nitrogen and argon gas at pressure of 10 exp 5 Pa (1 bar) was utilized to fill the ionization chamber, for which an appropriate configuration was determined to be used as a detector for high-dose measurements. To transmit the signal generated in the ionization chamber to the associated electronic and processing unit, a 20 m mineral insulated cable was welded to the ionization chamber. The signal to noise ratio produced by the detector was about 100. The dosimeter system was tested at a category I gamma

  18. Dose measurements in mammography

    International Nuclear Information System (INIS)

    Kainberger, F.; Kallinger, W.

    1977-01-01

    Dose measurements at the mamma during mammography were carried out in the form of direct measurement with thermoluminescent dosimetry. Measurement was done for the in- and outcoming doses at the mamma, the dose exposure of the sternal region and the scattered rays above the symphysis, the latter as parameter for the genetic radiation exposure. As expected, the dose of the smooth radiation used for mammography showed a strong decrease at the outcome point in comparison with the income point. Surprisingly high was the scattered radiation in the sternal region. A corresponding protection by lead plates could be taken into consideration. Extremely low is the scattered radiation above the symphysis. Even measurements with the very sensitive calcium fluoride dosimeters did not reveal any practically important dose in the symphysis region. Most measurement values remained below the determinable dose of 0.3mR. Some maximal values varied in the range of 3-1 mR. (orig.) [de

  19. Optimal registration conditions for tooth EPR dosimetry at low accumulated dose

    International Nuclear Information System (INIS)

    Galtsev, V.E.; Galtseva, E.V.; Lebedev, Y.S.

    1997-01-01

    The spectrum registration under rapid passage conditions (the second harmonic phase quadrature of the absorption signal) allows one to enhance substantially the sensitivity of tooth enamel and bone EPR dosimetry at a low accumulated dose. In the present work the dependencies of the radiation and background signals on EPR spectrometer parameters are described and the optimal conditions in RPM for EPR dosimetry are obtained. (Author)

  20. SU-E-J-109: Evaluation of Deformable Accumulated Parotid Doses Using Different Registration Algorithms in Adaptive Head and Neck Radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Xu, S [Key Laboratory of Particle & Radiation Imaging (Tsinghua University), Ministry of Education, Beijing, 100084 China (China); Chinese PLA General Hospital, Beijing, 100853 China (China); Liu, B [Image processing center, Beihang University, Beijing, 100191 China (China)

    2015-06-15

    Purpose: Three deformable image registration (DIR) algorithms are utilized to perform deformable dose accumulation for head and neck tomotherapy treatment, and the differences of the accumulated doses are evaluated. Methods: Daily MVCT data for 10 patients with pathologically proven nasopharyngeal cancers were analyzed. The data were acquired using tomotherapy (TomoTherapy, Accuray) at the PLA General Hospital. The prescription dose to the primary target was 70Gy in 33 fractions.Three DIR methods (B-spline, Diffeomorphic Demons and MIMvista) were used to propagate parotid structures from planning CTs to the daily CTs and accumulate fractionated dose on the planning CTs. The mean accumulated doses of parotids were quantitatively compared and the uncertainties of the propagated parotid contours were evaluated using Dice similarity index (DSI). Results: The planned mean dose of the ipsilateral parotids (32.42±3.13Gy) was slightly higher than those of the contralateral parotids (31.38±3.19Gy)in 10 patients. The difference between the accumulated mean doses of the ipsilateral parotids in the B-spline, Demons and MIMvista deformation algorithms (36.40±5.78Gy, 34.08±6.72Gy and 33.72±2.63Gy ) were statistically significant (B-spline vs Demons, P<0.0001, B-spline vs MIMvista, p =0.002). And The difference between those of the contralateral parotids in the B-spline, Demons and MIMvista deformation algorithms (34.08±4.82Gy, 32.42±4.80Gy and 33.92±4.65Gy ) were also significant (B-spline vs Demons, p =0.009, B-spline vs MIMvista, p =0.074). For the DSI analysis, the scores of B-spline, Demons and MIMvista DIRs were 0.90, 0.89 and 0.76. Conclusion: Shrinkage of parotid volumes results in the dose increase to the parotid glands in adaptive head and neck radiotherapy. The accumulated doses of parotids show significant difference using the different DIR algorithms between kVCT and MVCT. Therefore, the volume-based criterion (i.e. DSI) as a quantitative evaluation of

  1. Measurements Of Fingers Doses Of Staff Members In Nuclear Medicine Department

    International Nuclear Information System (INIS)

    AL LEHYANI, S.H.; SHOUSHA, H.A.; HASSAN, R.A.

    2009-01-01

    For some occupationally radiation exposed groups, the hands are more heavily exposed to ionizing radiation than the rest of the body. The Egyptian Atomic Energy Authority runs an extensive personal dosimetry service in Egypt, but finger doses have not been measured to a wide extent. In this study, the finger doses were measured for five different nuclear medicine staff occupational groups for which heavy irradiation of the hands was suspected. Finger doses were measured for nuclear medicine physicians, technologists, nurses and physicists. The nuclear medicine staff working with the radioactive materials wears two TLD dosimeters during the whole period, which lasted from 1 to 4 weeks. The staff performs their work on a regular basis throughout the month, and means annual doses were calculated for these groups. The doses to the fingers for the 99m Tc technologists and nurses of groups (2) and (3) were observed to be 30.24 ± 14.5 μSv/GBq (mean ± SD) and 30.37 ± 17.5 μSv/GBq, respectively. Similarly, the dose to the fingers for the 131 I technologists in group (5) was estimated to be 126.13 ± 38.2μSv/GBq. Finger doses for the physicians could not be calculated per unit of activity because they did not handle the radiopharmaceuticals directly but their doses were reported in millisieverts that accumulated in 1 week. The doses to the fingers of the physicist were 16.3±7.7 μSv/GBq. The maximum average finger dose in this study was found to be 2.8 mSv for the technologists handled therapeutic 131 I (group 5). It could be concluded that the maximum expected annual dose to the extremities appeared to be less than the annual limit (500 mSv/y).

  2. Intercomparison On Depth Dose Measurement

    International Nuclear Information System (INIS)

    Rohmah, N; Akhadi, M

    1996-01-01

    Intercomparation on personal dose evaluation system has been carried out between CSRSR-NAEA of Indonesia toward Standard Laboratory of JAERI (Japan) and ARL (Australia). The intercomparison was in 10 amm depth dose measurement , Hp (10), from the intercomparison result could be stated that personal depth dose measurement conducted by CSRSR was sufficiently good. Deviation of dose measurement result using personal dosemeter of TLD BG-1 type which were used by CSRSR in the intercomparison and routine photon personal dose monitoring was still in internationally agreed limit. Maximum deviation of reported doses by CSRSR compared to delivered doses for dosemeter irradiation by JAERI was -10.0 percent and by ARL was +29 percent. Maximum deviation permitted in personal dose monitoring is ± 50 percent

  3. Zinc accumulation potential and toxicity threshold determined for a metal-accumulating Populus canescens clone in a dose-response study

    Energy Technology Data Exchange (ETDEWEB)

    Langer, Ingrid [Institute of Soil Science, University of Natural Resources and Applied Life Sciences, Peter Jordan-Strasse 82, A-1190 Vienna (Austria); Krpata, Doris [Institute of Microbiology, Innsbruck University, Technikerstrasse 25, A-6020 Innsbruck (Austria); Fitz, Walter J.; Wenzel, Walter W. [Institute of Soil Science, University of Natural Resources and Applied Life Sciences, Peter Jordan-Strasse 82, A-1190 Vienna (Austria); Schweiger, Peter F., E-mail: peter.schweiger@boku.ac.a [Institute of Soil Science, University of Natural Resources and Applied Life Sciences, Peter Jordan-Strasse 82, A-1190 Vienna (Austria)

    2009-10-15

    The effect of increasing soil Zn concentrations on growth and Zn tissue concentrations of a metal-accumulating aspen clone was examined in a dose-response study. Plants were grown in a soil with a low native Zn content which was spiked with Zn salt solutions and subsequently aged. Plant growth was not affected by NH{sub 4}NO{sub 3}-extractable soil Zn concentrations up to 60 mug Zn g{sup -1} soil, but it was completely inhibited at extractable concentrations above 90 mug Zn g{sup -1} soil. From these data an effective concentration of 68.5 mug extractable Zn g{sup -1} soil was calculated at which plant growth was reduced by 50%. The obtained information on toxicity threshold concentrations, and the relation between plant Zn accumulation and extractable soil Zn concentrations may be used to assess the suitability of the investigated Populus canescens clone for various phytoremediation strategies. The potential risk of metal transfer into food webs associated with P. canescens stands on Zn-polluted sites may also be estimated. - Quantitative information about the concentration-dependent Zn accumulation of Populus canescens contributes to assess its suitability for phytoremediation.

  4. Understanding reduced inorganic mercury accumulation in rice following selenium application: Selenium application routes, speciation and doses.

    Science.gov (United States)

    Tang, Wenli; Dang, Fei; Evans, Douglas; Zhong, Huan; Xiao, Lin

    2017-02-01

    Selenium (Se) has recently been demonstrated to reduce inorganic mercury (IHg) accumulation in rice plants, while its mechanism is far from clear. Here, we aimed at exploring the potential effects of Se application routes (soil or foliar application with Se), speciation (selenite and selenate), and doses on IHg-Se antagonistic interactions in soil-rice systems. Results of our pot experiments indicated that soil application but not foliar application could evidently reduce tissue IHg concentrations (root: 0-48%, straw: 15-58%, and brown rice: 26-74%), although both application routes resulted in comparable Se accumulation in aboveground tissues. Meanwhile, IHg distribution in root generally increased with amended Se doses in soil, suggesting antagonistic interactions between IHg and Se in root. These results provided initial evidence that IHg-Se interactions in the rhizosphere (i.e., soil or rice root), instead of those in the aboveground tissues, could probably be more responsible for the reduced IHg bioaccumulation following Se application. Furthermore, Se dose rather than Se speciation was found to be more important in controlling IHg accumulation in rice. Our findings regarding the importance of IHg-Se interactions in the rhizosphere, together with the systematic investigation of key factors affecting IHg-Se antagonism and IHg bioaccumulation, advance our understanding of Hg dynamics in soil-rice systems. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Surface membrane based bladder registration for evaluation of accumulated dose during brachytherapy in cervical cancer

    DEFF Research Database (Denmark)

    Noe, Karsten Østergaard; Tanderup, Kari; Sørensen, Thomas Sangild

    2011-01-01

    of the fixed surface. Optional landmark based matches can be included in the suggested iterative solver. The technique is demonstrated for bladder registration in brachytherapy treatment evaluation of cervical cancer. It holds promise to better estimate the accumulated but unintentional dose delivered...

  6. Analysis of Cumulative Dose to Implanted Pacemaker According to Various IMRT Delivery Methods: Optimal Dose Delivery Versus Dose Reduction Strategy

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jeong Woo; Hong, Se Mie [Dept. of Radiation Oncology, Konkuk University Medical Center, Seoul (Korea, Republic of)

    2011-11-15

    Cancer patients with implanted cardiac pacemaker occasionally require radiotherapy. Pacemaker may be damaged or malfunction during radiotherapy due to ionizing radiation or electromagnetic interference. Although radiotherapy should be planned to keep the dose to pacemaker as low as possible not to malfunction ideally, current radiation treatment planning (RTP) system does not accurately calculate deposited dose to adjacent field border or area beyond irradiated fields. In terms of beam delivery techniques using multiple intensity modulated fields, dosimetric effect of scattered radiation in high energy photon beams is required to be detailed analyzed based on measurement data. The aim of this study is to evaluate dose discrepancies of pacemaker in a RTP system as compared to measured doses. We also designed dose reduction strategy limited value of 2 Gy for radiation treatment patients with cardiac implanted pacemaker. Total accumulated dose of 145 cGy based on in-vivo dosimetry was satisfied with the recommendation criteria to prevent malfunction of pacemaker in SS technique. However, the 2 mm lead shielder enabled the scattered doses to reduce up to 60% and 40% in the patient and the phantom, respectively. The SS technique with the lead shielding could reduce the accumulated scattered doses less than 100 cGy. Calculated and measured doses were not greatly affected by the beam delivery techniques. In-vivo and measured doses on pacemaker position showed critical dose discrepancies reaching up to 4 times as compared to planned doses in RTP. The current SS technique could deliver lower scattered doses than recommendation criteria, but use of 2 mm lead shielder contributed to reduce scattered doses by 60%. The tertiary lead shielder can be useful to prevent malfunction or electrical damage of implanted pacemakers during radiotherapy. It is required to estimate more accurate scattered doses of the patient or medical device in RTP to design proper dose reduction strategy.

  7. Analysis of Cumulative Dose to Implanted Pacemaker According to Various IMRT Delivery Methods: Optimal Dose Delivery Versus Dose Reduction Strategy

    International Nuclear Information System (INIS)

    Lee, Jeong Woo; Hong, Se Mie

    2011-01-01

    Cancer patients with implanted cardiac pacemaker occasionally require radiotherapy. Pacemaker may be damaged or malfunction during radiotherapy due to ionizing radiation or electromagnetic interference. Although radiotherapy should be planned to keep the dose to pacemaker as low as possible not to malfunction ideally, current radiation treatment planning (RTP) system does not accurately calculate deposited dose to adjacent field border or area beyond irradiated fields. In terms of beam delivery techniques using multiple intensity modulated fields, dosimetric effect of scattered radiation in high energy photon beams is required to be detailed analyzed based on measurement data. The aim of this study is to evaluate dose discrepancies of pacemaker in a RTP system as compared to measured doses. We also designed dose reduction strategy limited value of 2 Gy for radiation treatment patients with cardiac implanted pacemaker. Total accumulated dose of 145 cGy based on in-vivo dosimetry was satisfied with the recommendation criteria to prevent malfunction of pacemaker in SS technique. However, the 2 mm lead shielder enabled the scattered doses to reduce up to 60% and 40% in the patient and the phantom, respectively. The SS technique with the lead shielding could reduce the accumulated scattered doses less than 100 cGy. Calculated and measured doses were not greatly affected by the beam delivery techniques. In-vivo and measured doses on pacemaker position showed critical dose discrepancies reaching up to 4 times as compared to planned doses in RTP. The current SS technique could deliver lower scattered doses than recommendation criteria, but use of 2 mm lead shielder contributed to reduce scattered doses by 60%. The tertiary lead shielder can be useful to prevent malfunction or electrical damage of implanted pacemakers during radiotherapy. It is required to estimate more accurate scattered doses of the patient or medical device in RTP to design proper dose reduction strategy.

  8. Do dose area product meter measurements reflect radiation doses ...

    African Journals Online (AJOL)

    Enrique

    SA JOURNAL OF RADIOLOGY • August 2004. Abstract. This study determined the correlation between radiation doses absorbed by health care workers and dose area product meter (DAP) measurements at Universitas Hospital, Bloemfontein. The DAP is an instrument which accurately measures the radiation emitted from ...

  9. Do dose area product meter measurements reflect radiation doses ...

    African Journals Online (AJOL)

    This study determined the correlation between radiation doses absorbed by health care workers and dose area product meter (DAP) measurements at Universitas Hospital, Bloemfontein. The DAP is an instrument which accurately measures the radiation emitted from the source. The study included the interventional ...

  10. SU-F-J-68: Deformable Dose Accumulation for Voxel-Based Dose Tracking of PTV Cold Spots for Adaptive Radiotherapy of the Head and Neck

    Energy Technology Data Exchange (ETDEWEB)

    Liu, C; Chetty, I; Mao, W; Kumarasiri, A; Zhong, H; Brown, S; Siddiqui, F [Henry Ford Health System, Detroit, MI (United States)

    2016-06-15

    Purpose: To utilize deformable dose accumulation (DDA) to determine how cold spots within the PTV change over the course of fractionated head and neck (H&N) radiotherapy. Methods: Voxel-based dose was tracked using a DDA platform. The DDA process consisted of B-spline-based deformable image registration (DIR) and dose accumulation between planning CT’s and daily cone-beam CT’s for 10 H&N cancer patients. Cold spots within the PTV (regions receiving less than the prescription, 70 Gy) were contoured on the cumulative dose distribution. These cold spots were mapped to each fraction, starting from the first fraction to determine how they changed. Spatial correlation between cold spot regions over each fraction, relative to the last fraction, was computed using the Jaccard index Jk (Mk,N), where N is the cold spot within the PTV at the end of the treatment, and Mk the same region for fraction k. Results: Figure 1 shows good spatial correlation between cold spots, and highlights expansion of the cold spot region over the course of treatment, as a result of setup uncertainties, and anatomical changes. Figure 2 shows a plot of Jk versus fraction number k averaged over 10 patients. This confirms the good spatial correlation between cold spots over the course of treatment. On average, Jk reaches ∼90% at fraction 22, suggesting that possible intervention (e.g. reoptimization) may mitigate the cold spot region. The cold spot, D99, averaged over 10 patients corresponded to a dose of ∼65 Gy, relative to the prescription dose of 70 Gy. Conclusion: DDA-based tracking provides spatial dose information, which can be used to monitor dose in different regions of the treatment plan, thereby enabling appropriate mid-treatment interventions. This work is supported in part by Varian Medical Systems, Palo Alto, CA.

  11. Dose rate measuring device and dose rate measuring method using the same

    International Nuclear Information System (INIS)

    Urata, Megumu; Matsushita, Takashi; Hanazawa, Sadao; Konno, Takahiro; Chiba, Yoshinori; Yumitate, Tadahiro

    1998-01-01

    The device of the present invention comprises a scintillation fiber scope having a shape elongated in the direction of the height of a pressure vessel and emitting light by incident of radiation to detect radiation, a radioactivity measuring device for measuring a dose rate based on the detection of the fiber scope and a reel means for dispensing and taking up the fiber scope, and it constituted such that the dose rate of the pressure vessel and that of a shroud are determined independently. Then, when the taken out shroud is contained in an container, excessive shielding is not necessary, in addition, this device can reliably be inserted to or withdrawn from complicated places between the pressure vessel and the shroud, and further, the dose rate of the pressure vessel and that of the shroud can be measured approximately accurately even when the thickness of them is different greatly. (N.H.)

  12. Dose rate measuring device and dose rate measuring method using the same

    Energy Technology Data Exchange (ETDEWEB)

    Urata, Megumu; Matsushita, Takashi; Hanazawa, Sadao; Konno, Takahiro; Chiba, Yoshinori; Yumitate, Tadahiro

    1998-11-13

    The device of the present invention comprises a scintillation fiber scope having a shape elongated in the direction of the height of a pressure vessel and emitting light by incident of radiation to detect radiation, a radioactivity measuring device for measuring a dose rate based on the detection of the fiber scope and a reel means for dispensing and taking up the fiber scope, and it constituted such that the dose rate of the pressure vessel and that of a shroud are determined independently. Then, when the taken out shroud is contained in an container, excessive shielding is not necessary, in addition, this device can reliably be inserted to or withdrawn from complicated places between the pressure vessel and the shroud, and further, the dose rate of the pressure vessel and that of the shroud can be measured approximately accurately even when the thickness of them is different greatly. (N.H.)

  13. MO-C-17A-10: Comparison of Dose Deformable Accumulation by Using Parallel and Serial Approaches

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Z; Li, M; Wong, J [Morristown Medical Center, Morristown, NJ (United States)

    2014-06-15

    Purpose: The uncertainty of dose accumulation over multiple CT datasets with deformable fusion may have significant impact on clinical decisions. In this study, we investigate the difference of two dose summation approaches involving deformable fusion. Methods: Five patients, four external beam and one brachytherapy(BT), were chosen for the study. The BT patient was treated with CT-based HDR. The CT image sets acquired in the imageguidance process (8-11 CTs/patient) were used to determine the dose delivered to the four external beam patients. (prostate, pelvis, lung and head and neck). For the HDR patient (cervix), five CT image sets and the corresponding BT plans were used. In total 44 CT datasets and RT dose/plans were imported into the image fusion software MiM (6.0.4) for analysis.For each of the five clinical cases, the dose from each fraction was accumulated into the primary CT dataset by using both Parallel and Serial approaches. The dose-volume histogram (DVH) for CTV and selected organs-at-risks (OAR) were generated. The D95(CTV), OAR(mean) and OAR(max) for the four external beam cases the D90(CTV), and the max dose to bladder and rectum for the BT case were compared. Results: For the four external beam patients, the difference in D95(CTV) were <1.2% PD between the parallel and the serial approaches. The differences of the OAR(mean) and the OAR(max ) range from 0 to 3.7% and <1% PD respectively. For the HDR patient, the dose difference for D90 is 11% PD while that of the max dose to bladder and rectum were 11.5% and 23.3% respectively. Conclusion: For external beam treatments, the parallel and serial approaches have <5% difference probably because tumor volume and OAR have less changes from fraction to fraction. For the brachytherapy case, >10% dose difference between the two approaches was observed as significant volume changes of tumor and OAR were observed among treatment fractions.

  14. Bladder dose accumulation based on a biomechanical deformable image registration algorithm in volumetric modulated arc therapy for prostate cancer

    DEFF Research Database (Denmark)

    Andersen, E S; Muren, L P; Sørensen, T S

    2012-01-01

    Variations in bladder position, shape and volume cause uncertainties in the doses delivered to this organ during a course of radiotherapy for pelvic tumors. The purpose of this study was to evaluate the potential of dose accumulation based on repeat imaging and deformable image registration (DIR)...

  15. Patient dose measurement and dose reduction in East Anglia (UK)

    International Nuclear Information System (INIS)

    Wade, J.P.; Goldstone, K.E.; Dendy, P.P.

    1995-01-01

    At the end of 1990 a programme of patient dose measurements was introduced as part of the quality assurance service already provided for X ray departments throughout the East Anglian Health Region (UK). Thermoluminescence dosemeters (TLDs) were used to measure over 1200 skin entrance surface doses for four common radiographic views in 33 hospitals in both the NHS and private sector. The four views were chosen to cover a wide range of equipment and techniques. The data collected have enabled Regional reference doses to be set which, for all views considered, fall below the National Radiological Protection Board (NRPB) Reference levels. In departments which exceeded reference levels, techniques were reviewed, improvements suggested and doses re-measured, in accordance with the recommended procedure for patient dose audit. A significant finding was that, given appropriate controls, X ray departments in the private sector could achieve the same acceptably low doses as NHS departments. (Author)

  16. PABLM: a computer program to calculate accumulated radiation doses from radionuclides in the environment

    Energy Technology Data Exchange (ETDEWEB)

    Napier, B.A.; Kennedy, W.E. Jr.; Soldat, J.K.

    1980-03-01

    A computer program, PABLM, was written to facilitate the calculation of internal radiation doses to man from radionuclides in food products and external radiation doses from radionuclides in the environment. This report contains details of mathematical models used and calculational procedures required to run the computer program. Radiation doses from radionuclides in the environment may be calculated from deposition on the soil or plants during an atmospheric or liquid release, or from exposure to residual radionuclides in the environment after the releases have ended. Radioactive decay is considered during the release of radionuclides, after they are deposited on the plants or ground, and during holdup of food after harvest. The radiation dose models consider several exposure pathways. Doses may be calculated for either a maximum-exposed individual or for a population group. The doses calculated are accumulated doses from continuous chronic exposure. A first-year committed dose is calculated as well as an integrated dose for a selected number of years. The equations for calculating internal radiation doses are derived from those given by the International Commission on Radiological Protection (ICRP) for body burdens and MPC's of each radionuclide. The radiation doses from external exposure to contaminated water and soil are calculated using the basic assumption that the contaminated medium is large enough to be considered an infinite volume or plane relative to the range of the emitted radiations. The equations for calculations of the radiation dose from external exposure to shoreline sediments include a correction for the finite width of the contaminated beach.

  17. PABLM: a computer program to calculate accumulated radiation doses from radionuclides in the environment

    International Nuclear Information System (INIS)

    Napier, B.A.; Kennedy, W.E. Jr.; Soldat, J.K.

    1980-03-01

    A computer program, PABLM, was written to facilitate the calculation of internal radiation doses to man from radionuclides in food products and external radiation doses from radionuclides in the environment. This report contains details of mathematical models used and calculational procedures required to run the computer program. Radiation doses from radionuclides in the environment may be calculated from deposition on the soil or plants during an atmospheric or liquid release, or from exposure to residual radionuclides in the environment after the releases have ended. Radioactive decay is considered during the release of radionuclides, after they are deposited on the plants or ground, and during holdup of food after harvest. The radiation dose models consider several exposure pathways. Doses may be calculated for either a maximum-exposed individual or for a population group. The doses calculated are accumulated doses from continuous chronic exposure. A first-year committed dose is calculated as well as an integrated dose for a selected number of years. The equations for calculating internal radiation doses are derived from those given by the International Commission on Radiological Protection (ICRP) for body burdens and MPC's of each radionuclide. The radiation doses from external exposure to contaminated water and soil are calculated using the basic assumption that the contaminated medium is large enough to be considered an infinite volume or plane relative to the range of the emitted radiations. The equations for calculations of the radiation dose from external exposure to shoreline sediments include a correction for the finite width of the contaminated beach

  18. SU-E-I-45: Measurement of CT Dose to An HDPE Phantom Using Calorimetry: A Feasibility Study.

    Science.gov (United States)

    Chen-Mayer, H; Tosh, R; Bateman, F; Zimmerman, B

    2012-06-01

    Radiation dose in CT is traditionally evaluated using an ionization chamber calibrated in terms of air kerma in a phantom of specific dimensions. The radiation absorbed dose, J/kg, can also be realized directly by measuring the temperature rise in the medium. We investigate using this primary method to determine the CT dose at a point (a few mm), using the recently proposed (APMM TG220) high density polyethylene (HDPE) phantom as a medium. The calorimeter detection scheme is adapted from the second generation NIST water calorimeter using sensitive thermistors in a Wheatstone bridge powered by a lock-in amplifier. The temperature sensitivity is about 3 microK. The expected temperature rise in PE is about 0.6 mK per Gy. The thermistor sensors were placed inside a 26 cm dia. × 10 cm HDPE phantom. Two preliminary tests were made: at a linear accelerator with a 6 MV photon beam, and at a 16-slice CT scanner with a 120 kV beam, each with the thermal sensor and with a calibrated ionization chamber. The 6 MV photon beam with 10 on/off cycles at 60 s each yielded the (uncorrected) run-to-run average dose of 3.06 Gy per cycle (sdm 0.3%), about 8% higher than the Result from the ionization chamber (calibrated in terms of absorbed to water). The CT measurements were also made in the middle section of the TG200 30 cm phantom. Twenty consecutive axial scans at 250 mA, which delivers a nominal accumulated dose (CTDIvol) of 705 mGy in 50 s at three axial and three radial locations were measured. The accumulated dose measured by the ionization chamber at the center of the smaller phantom was 347 mGy. The calorimeter data show qualitative tracking of the chamber measurements. Detailed thermal and electrical analysis of the system are planned to obtain quantitative results. © 2012 American Association of Physicists in Medicine.

  19. Dose in the uterus of a woman, with three months of pregnancy, due to the 131 I accumulated in her thyroid gland

    International Nuclear Information System (INIS)

    Vega C, H.R.; Manzanares A, E.; Hernandez D, V.M.; Arcos P, A.

    2006-01-01

    In this study the absorbed dose by the uterus of a woman with three months of pregnancy to who was applied a dose of 131 I that was accumulated in the thyroid gland is determined. The absorbed dose was obtained by means of Monte Carlo calculations developing a detailed three-dimensional model of the pregnant one, where they have been included most of the organs. The absorbed dose also was calculated by means of a simple procedure. To verify the calculated results it was carried out an experiment where was constructed a phantom of the neck, in this was included the thyroid with 131 I and the exposure was measured at different distances of the neck; this was related with the dose. Of the Monte Carlo calculation is obtained that for each mCi of 131 I that is retained in the mother's thyroid, the uterus absorbs a dose of 6.80 E(-11) Gy. When comparing the results, it was found that the simple calculation throws a result 29 times superior to that of the dose obtained by means of Monte Carlo. When applying a correction for the effect of the absorption of the gamma photons by the mother's body an absorbed dose in the uterus was obtained that is 0.16 times superior to the Monte Carlo calculation. Of the experimental phase it is verified that the values calculated by means of the simple method are equal to those experimentally measured. (Author)

  20. Entrance and peripheral dose measurements during radiotherapy

    International Nuclear Information System (INIS)

    Sulieman, A.; Kappas, K.; Theodorou, K.

    2008-01-01

    In vivo dosimetry of entrance dose was performed using thermoluminescent dosimeters (TLD) in order to evaluate the clinical application of the build up caps in patient dose measurements and for different treatment techniques. Peripheral dose (thyroid and skin) was measured for patients during breast radiotherapy to evaluate the probability of secondary cancer induction. TLD-100 chips were used with different Copper build up caps (for 6 MV and 15 MV photon beams from two linear accelerators. Entrance doses were measured for patients during radiotherapy course for breast, head and neck, abdomen and pelvis malignancies. The measured entrance dose for the different patients for 6 MV beams is found to be within the ±2.6% compared to the dose derived from theoretical estimation (normalized dose at D max ). The same measurements for 15 MV beams are found to be ±3 %. The perturbation value can reach up to 20% of the D max , which acts as a limitation for entrance dose measurements. An average thyroid skin dose of 3.7% of the prescribed dose was measured per treatment session while the mean skin dose breast treatment session is estimated to be 42% of D max , for both internal and external fields. These results are comparable in those of the in vivo of reported in literature. The risk of fatality due to thyroid cancer per treatment course is 3x10 -3

  1. Improving anatomical mapping of complexly deformed anatomy for external beam radiotherapy and brachytherapy dose accumulation in cervical cancer

    International Nuclear Information System (INIS)

    Vásquez Osorio, Eliana M.; Kolkman-Deurloo, Inger-Karine K.; Schuring-Pereira, Monica; Zolnay, András; Heijmen, Ben J. M.; Hoogeman, Mischa S.

    2015-01-01

    Purpose: In the treatment of cervical cancer, large anatomical deformations, caused by, e.g., tumor shrinkage, bladder and rectum filling changes, organ sliding, and the presence of the brachytherapy (BT) applicator, prohibit the accumulation of external beam radiotherapy (EBRT) and BT dose distributions. This work proposes a structure-wise registration with vector field integration (SW+VF) to map the largely deformed anatomies between EBRT and BT, paving the way for 3D dose accumulation between EBRT and BT. Methods: T2w-MRIs acquired before EBRT and as a part of the MRI-guided BT procedure for 12 cervical cancer patients, along with the manual delineations of the bladder, cervix-uterus, and rectum-sigmoid, were used for this study. A rigid transformation was used to align the bony anatomy in the MRIs. The proposed SW+VF method starts by automatically segmenting features in the area surrounding the delineated organs. Then, each organ and feature pair is registered independently using a feature-based nonrigid registration algorithm developed in-house. Additionally, a background transformation is calculated to account for areas far from all organs and features. In order to obtain one transformation that can be used for dose accumulation, the organ-based, feature-based, and the background transformations are combined into one vector field using a weighted sum, where the contribution of each transformation can be directly controlled by its extent of influence (scope size). The optimal scope sizes for organ-based and feature-based transformations were found by an exhaustive analysis. The anatomical correctness of the mapping was independently validated by measuring the residual distances after transformation for delineated structures inside the cervix-uterus (inner anatomical correctness), and for anatomical landmarks outside the organs in the surrounding region (outer anatomical correctness). The results of the proposed method were compared with the results of the

  2. Improving anatomical mapping of complexly deformed anatomy for external beam radiotherapy and brachytherapy dose accumulation in cervical cancer

    Energy Technology Data Exchange (ETDEWEB)

    Vásquez Osorio, Eliana M., E-mail: e.vasquezosorio@erasmusmc.nl; Kolkman-Deurloo, Inger-Karine K.; Schuring-Pereira, Monica; Zolnay, András; Heijmen, Ben J. M.; Hoogeman, Mischa S. [Department of Radiation Oncology, Erasmus MC Cancer Institute, Rotterdam 3075 (Netherlands)

    2015-01-15

    Purpose: In the treatment of cervical cancer, large anatomical deformations, caused by, e.g., tumor shrinkage, bladder and rectum filling changes, organ sliding, and the presence of the brachytherapy (BT) applicator, prohibit the accumulation of external beam radiotherapy (EBRT) and BT dose distributions. This work proposes a structure-wise registration with vector field integration (SW+VF) to map the largely deformed anatomies between EBRT and BT, paving the way for 3D dose accumulation between EBRT and BT. Methods: T2w-MRIs acquired before EBRT and as a part of the MRI-guided BT procedure for 12 cervical cancer patients, along with the manual delineations of the bladder, cervix-uterus, and rectum-sigmoid, were used for this study. A rigid transformation was used to align the bony anatomy in the MRIs. The proposed SW+VF method starts by automatically segmenting features in the area surrounding the delineated organs. Then, each organ and feature pair is registered independently using a feature-based nonrigid registration algorithm developed in-house. Additionally, a background transformation is calculated to account for areas far from all organs and features. In order to obtain one transformation that can be used for dose accumulation, the organ-based, feature-based, and the background transformations are combined into one vector field using a weighted sum, where the contribution of each transformation can be directly controlled by its extent of influence (scope size). The optimal scope sizes for organ-based and feature-based transformations were found by an exhaustive analysis. The anatomical correctness of the mapping was independently validated by measuring the residual distances after transformation for delineated structures inside the cervix-uterus (inner anatomical correctness), and for anatomical landmarks outside the organs in the surrounding region (outer anatomical correctness). The results of the proposed method were compared with the results of the

  3. Mixed field dose equivalent measuring instruments

    International Nuclear Information System (INIS)

    Brackenbush, L.W.; McDonald, J.C.; Endres, G.W.R.; Quam, W.

    1985-01-01

    In the past, separate instruments have been used to monitor dose equivalent from neutrons and gamma rays. It has been demonstrated that it is now possible to measure simultaneously neutron and gamma dose with a single instrument, the tissue equivalent proportional counter (TEPC). With appropriate algorithms dose equivalent can also be determined from the TEPC. A simple ''pocket rem meter'' for measuring neutron dose equivalent has already been developed. Improved algorithms for determining dose equivalent for mixed fields are presented. (author)

  4. SU-E-J-66: Significant Anatomical and Dosimetric Changes Observed with the Pharyngeal Constrictor During Head and Neck Radiotherapy Elicited From Daily Deformable Image Registration and Dose Accumulation

    International Nuclear Information System (INIS)

    Kumarasiri, A; Siddiqui, F; Liu, C; Kamal, M; Fraser, C; Chetty, I; Kim, J

    2015-01-01

    Purpose: To evaluate the anatomical changes and associated dosimetric consequences to the pharyngeal constrictor (PC) that occurs during head and neck radiotherapy (H&N RT). Methods: A cohort of 13 oro-pharyngeal cancer patients, who had daily CBCT’s for localization, was retrospectively studied. On every 5th CBCT, PC was manually delineated by a radiation oncologist. The anterior-posterior PC thickness was measured at the C3 level. Delivered dose to PC was estimated by calculating daily doses on CBCT’s, and accumulating to corresponding planning CT images. For accumulation, a parameter-optimized B- spline-based deformable image registration algorithm (Elastix) was used, in conjunction with an energy-mass mapping dose transfer algorithm. Mean and maximum dose (Dmean, Dmax) to PC was determined and compared with corresponding planned quantities. Results: The mean (±standard deviation) volume increase (ΔV) and thickness increase (Δt) over the course of 35 total fractions were 54±33% (11.9±7.6 cc), and 63±39% (2.9±1.9 mm), respectively. The resultant cumulative mean dose increase from planned dose to PC (ΔDmean) was 1.4±1.3% (0.9±0.8 Gy), while the maximum dose increase (ΔDmax) was 0.0±1.6% (0.0±1.1 Gy). Patients with adaptive replanning (n=6) showed a smaller mean dose increase than those without (n=7); 0.5±0.2% (0.3±0.1 Gy) vs. 2.2±1.4% (1.4±0.9 Gy). There was a statistically significant (p<0.0001) strong correlation between ΔDmean and Δt (Pearson coefficient r=0.78), and a moderate-to-strong correlation (r=0.52) between ΔDmean and ΔV. Correlation between ΔDmean and weight loss ΔW (r=0.1), as well as ΔV and ΔW (r=0.2) were negligible. Conclusion: Patients were found to undergo considerable anatomical changes to pharyngeal constrictor during H&N RT, resulting in non-negligible dose deviations from intended dose. Results are indicative that pharyngeal constrictor thickness, measured at C3 level, is a good predictor for the dose change to

  5. SU-E-J-66: Significant Anatomical and Dosimetric Changes Observed with the Pharyngeal Constrictor During Head and Neck Radiotherapy Elicited From Daily Deformable Image Registration and Dose Accumulation

    Energy Technology Data Exchange (ETDEWEB)

    Kumarasiri, A; Siddiqui, F; Liu, C; Kamal, M; Fraser, C; Chetty, I; Kim, J [Henry Ford Health System, Detroit, MI (United States)

    2015-06-15

    Purpose: To evaluate the anatomical changes and associated dosimetric consequences to the pharyngeal constrictor (PC) that occurs during head and neck radiotherapy (H&N RT). Methods: A cohort of 13 oro-pharyngeal cancer patients, who had daily CBCT’s for localization, was retrospectively studied. On every 5th CBCT, PC was manually delineated by a radiation oncologist. The anterior-posterior PC thickness was measured at the C3 level. Delivered dose to PC was estimated by calculating daily doses on CBCT’s, and accumulating to corresponding planning CT images. For accumulation, a parameter-optimized B- spline-based deformable image registration algorithm (Elastix) was used, in conjunction with an energy-mass mapping dose transfer algorithm. Mean and maximum dose (Dmean, Dmax) to PC was determined and compared with corresponding planned quantities. Results: The mean (±standard deviation) volume increase (ΔV) and thickness increase (Δt) over the course of 35 total fractions were 54±33% (11.9±7.6 cc), and 63±39% (2.9±1.9 mm), respectively. The resultant cumulative mean dose increase from planned dose to PC (ΔDmean) was 1.4±1.3% (0.9±0.8 Gy), while the maximum dose increase (ΔDmax) was 0.0±1.6% (0.0±1.1 Gy). Patients with adaptive replanning (n=6) showed a smaller mean dose increase than those without (n=7); 0.5±0.2% (0.3±0.1 Gy) vs. 2.2±1.4% (1.4±0.9 Gy). There was a statistically significant (p<0.0001) strong correlation between ΔDmean and Δt (Pearson coefficient r=0.78), and a moderate-to-strong correlation (r=0.52) between ΔDmean and ΔV. Correlation between ΔDmean and weight loss ΔW (r=0.1), as well as ΔV and ΔW (r=0.2) were negligible. Conclusion: Patients were found to undergo considerable anatomical changes to pharyngeal constrictor during H&N RT, resulting in non-negligible dose deviations from intended dose. Results are indicative that pharyngeal constrictor thickness, measured at C3 level, is a good predictor for the dose change to

  6. Endocrine activity of persistent organic pollutants accumulated in human silicone implants — Dosing in vitro assays by partitioning from silicone

    DEFF Research Database (Denmark)

    Gilbert, Dorothea; Mayer, Philipp; Pedersen, Mikael

    2015-01-01

    Persistent organic pollutants (POPs) accumulated in human tissues may pose a risk for human health by interfering with the endocrine system. This study establishes a new link between actual human internal POP levels and the endocrine active dose in vitro, applying partitioning-controlled dosing...

  7. Sci-Fri PM: Radiation Therapy, Planning, Imaging, and Special Techniques - 08: Retrospective Dose Accumulation Workflow in Head and Neck Cancer Patients Using RayStation 4.5.2

    International Nuclear Information System (INIS)

    Wong, Olive; Chan, Biu; Moseley, Joanne; McNiven, Andrea; Lindsay, Patricia; Bissonnette, Jean-Pierre; Waldron, John; Giuliani, Meredith; Zhang, Beibei

    2016-01-01

    Purpose: We have developed a semi-automated dose accumulation workflow for Head and Neck Cancer (HNC) patients to evaluate volumetric and dosimetric changes that take place during radiotherapy. This work will be used to assess how dosimetric changes affect both toxicity and disease control, hence inform the feasibility and design of a prospective HNC adaptive trial. Methods: RayStation 4.5.2 features deformable image registration (DIR), where structures already defined on the planning CT image set can be deformably mapped onto cone-beam computed tomography (CBCT) images, accounting for daily treatment set-up shifts and changes in patient anatomy. The daily delivered dose can be calculated on each CBCT and mapped back to the planning CT to allow dose accumulation. The process is partially automated using Python scripts developed in collaboration with RaySearch. Results: To date we have performed dose accumulation on 18 HNC patients treated at our institution during 2013–2015 under REB approval. Our semi-automated process establishes clinical feasibility. Generally, dose accumulation for the entire treatment course of one case takes 60–120 minutes: importing all CBCTs requires 20–30 minutes as each patient has 30 to 40 treated fractions; image registration and dose accumulation require 60–90 minutes. This is in contrast to the process without automated scripts where dose accumulation alone would take 3–5 hours. Conclusions: We have developed a reliable workflow for retrospective dose tracking in HNC using RayStation. The process has been validated for HNC patients treated on both Elekta and Varian linacs with CBCTs acquired on XVI and OBI platforms respectively.

  8. Sci-Fri PM: Radiation Therapy, Planning, Imaging, and Special Techniques - 08: Retrospective Dose Accumulation Workflow in Head and Neck Cancer Patients Using RayStation 4.5.2

    Energy Technology Data Exchange (ETDEWEB)

    Wong, Olive; Chan, Biu; Moseley, Joanne; McNiven, Andrea; Lindsay, Patricia; Bissonnette, Jean-Pierre; Waldron, John; Giuliani, Meredith; Zhang, Beibei [Princess Margaret Cancer Centre-UHN (Canada)

    2016-08-15

    Purpose: We have developed a semi-automated dose accumulation workflow for Head and Neck Cancer (HNC) patients to evaluate volumetric and dosimetric changes that take place during radiotherapy. This work will be used to assess how dosimetric changes affect both toxicity and disease control, hence inform the feasibility and design of a prospective HNC adaptive trial. Methods: RayStation 4.5.2 features deformable image registration (DIR), where structures already defined on the planning CT image set can be deformably mapped onto cone-beam computed tomography (CBCT) images, accounting for daily treatment set-up shifts and changes in patient anatomy. The daily delivered dose can be calculated on each CBCT and mapped back to the planning CT to allow dose accumulation. The process is partially automated using Python scripts developed in collaboration with RaySearch. Results: To date we have performed dose accumulation on 18 HNC patients treated at our institution during 2013–2015 under REB approval. Our semi-automated process establishes clinical feasibility. Generally, dose accumulation for the entire treatment course of one case takes 60–120 minutes: importing all CBCTs requires 20–30 minutes as each patient has 30 to 40 treated fractions; image registration and dose accumulation require 60–90 minutes. This is in contrast to the process without automated scripts where dose accumulation alone would take 3–5 hours. Conclusions: We have developed a reliable workflow for retrospective dose tracking in HNC using RayStation. The process has been validated for HNC patients treated on both Elekta and Varian linacs with CBCTs acquired on XVI and OBI platforms respectively.

  9. Changes of chromosome aberration rate and micronucleus frequency along with accumulated dose in continuously irradiated mice with a low dose rate of γ-rays

    International Nuclear Information System (INIS)

    Tanaka, Kimio; Izumi, Jun; Yanai, Takanori; Ichinohe, Kazuaki; Matsumoto, Tsuneya

    2003-01-01

    Chromosome aberrations in chronically exposed workers in nuclear facilities and medical radiologists have been reported. However chronological change of chromosome aberration rates along with accumulated dose has not been well studied. Chromosome aberrations and micronuclei in spleen lymphocytes were observed serially in mice continuously irradiated with a low dose rate of 20 mGy/day up to 400 days. Chromosome aberration rates were rapidly increased to 11.1% at 1 Gy, while micronucleus incidence increased at 5 Gy. After these doses their increase rates were saturated. Micronucleus incidence in bone marrow erythroblasts was higher than in spleen cells. These chronological changes of cytogenetic aberrations seem to be induced through a balance between developments of chromosome aberrations and micronuclei, and life span of spleen lymphocytes. These results will be helpful for risk assessment in low dose rate radiation exposure. (author)

  10. A Study on the Establishment of Radiation Dose Estimation Procedure for Accumulated Radioactive Ions for RAON ISOL System

    Directory of Open Access Journals (Sweden)

    KIM Do Hyun

    2017-01-01

    Full Text Available For purposes of various experiments, RAON heavy ion accelerator facility has been designed in Korea. ISOL is one system of RAON accelerators to generate and separate rare isotopes. Radioactive ions generated from target-proton reactions are separated and accumulated at separation devices. The accumulated isotopes release the gamma radiations; therefore, the radiation safety must be clearly estimated. In this study, a process to evaluate radiations from the accumulated ions was proposed by modifying FISPACT code. The proposed process was validated by comparing a solution of single element decay problem. Using the process, a preliminary study for radiation doses were performed in a virtual separation devise.

  11. Brachytherapy dose measurements in heterogeneous tissues

    International Nuclear Information System (INIS)

    Paiva F, G.; Luvizotto, J.; Salles C, T.; Guimaraes A, P. C.; Dalledone S, P. de T.; Yoriyaz, H.; Rubo, R.

    2014-08-01

    Recently, Beau lieu et al. published an article providing guidance for Model-Based Dose Calculation Algorithms (MBDCAs), where tissue heterogeneity considerations are addressed. It is well-known that T G-43 formalism which considers only water medium is limited and significant dose differences have been found comparing both methodologies. The aim of the present work is to experimentally quantify dose values in heterogeneous medium using different dose measurement methods and techniques and compare them with those obtained with Monte Carlo simulations. Experiments have been performed using a Nucletron micro Selectron-Hdr Ir-192 brachytherapy source and a heterogeneous phantom composed by PMMA and different tissue equivalent cylinders like bone, lungs and muscle. Several dose measurements were obtained using tissue equivalent materials with height 1.8 cm and 4.3 cm positioned between the radiation source and the detectors. Radiochromic films, TLDs and MOSFET S have been used for the dose measurements. Film dosimetry has been performed using two methodologies: a) linearization for dose-response curve based on calibration curves to create a functional form that linearize s the dose response and b) 177 multichannel analysis dosimetry where the multiple color channels are analyzed allowing to address not only disturbances in the measurements caused by thickness variation in the film layer, but also, separate other external influences in the film response. All experiments have been simulated using the MCNP5 Monte Carlo radiation transport code. Comparison of experimental results are in good agreement with calculated dose values with differences less than 6% for almost all cases. (Author)

  12. Brachytherapy dose measurements in heterogeneous tissues

    Energy Technology Data Exchange (ETDEWEB)

    Paiva F, G.; Luvizotto, J.; Salles C, T.; Guimaraes A, P. C.; Dalledone S, P. de T.; Yoriyaz, H. [Instituto de Pesquisas Energeticas e Nucleares / CNEN, Av. Lineu Prestes 2242, Cidade Universitaria, 05508-000 Sao Paulo (Brazil); Rubo, R., E-mail: gabrielpaivafonseca@gmail.com [Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, 05403-900 Sao Paulo (Brazil)

    2014-08-15

    Recently, Beau lieu et al. published an article providing guidance for Model-Based Dose Calculation Algorithms (MBDCAs), where tissue heterogeneity considerations are addressed. It is well-known that T G-43 formalism which considers only water medium is limited and significant dose differences have been found comparing both methodologies. The aim of the present work is to experimentally quantify dose values in heterogeneous medium using different dose measurement methods and techniques and compare them with those obtained with Monte Carlo simulations. Experiments have been performed using a Nucletron micro Selectron-Hdr Ir-192 brachytherapy source and a heterogeneous phantom composed by PMMA and different tissue equivalent cylinders like bone, lungs and muscle. Several dose measurements were obtained using tissue equivalent materials with height 1.8 cm and 4.3 cm positioned between the radiation source and the detectors. Radiochromic films, TLDs and MOSFET S have been used for the dose measurements. Film dosimetry has been performed using two methodologies: a) linearization for dose-response curve based on calibration curves to create a functional form that linearize s the dose response and b) 177 multichannel analysis dosimetry where the multiple color channels are analyzed allowing to address not only disturbances in the measurements caused by thickness variation in the film layer, but also, separate other external influences in the film response. All experiments have been simulated using the MCNP5 Monte Carlo radiation transport code. Comparison of experimental results are in good agreement with calculated dose values with differences less than 6% for almost all cases. (Author)

  13. Traceability and standardization of large dose measurement

    International Nuclear Information System (INIS)

    Tanaka, Ryuichi

    1989-01-01

    The reliability of dose control for radiation sterilization and food irradiation depends on the relative errors in measurements made by different dosimeters and the level of process control techniques as well as traceability. International efforts have been made for standardization of dose measurement procedures and process control techniques. A system for traceability of large dose measurement has already been established in the U.S. and Britain, and it has become urgent in Japan to establish a traceability system. For process control for radiation sterilization of medical tools, dose measurement is replacing the use of a biological indicator to play a more important role in relation to sterilization assurance. AAMI is making efforts to establish implementation standards for process control for industrial sterilization with electron beam. In Japan, the Radiation Irradiation Promotion Association has developed a manual 'Measurement of Dose of Electron Beam for Irradiation' to be used by users of electron beam for irradiation. Further efforts are required to establish a proper traceability system and standardization of dose measurement. (N.K.)

  14. Average dose to an organ per microcurie-day accumulated by a radionuclide in a source organ

    International Nuclear Information System (INIS)

    Snyder, W.S.; Ford, M.R.

    1975-01-01

    Methods are discussed that are used in calculations of the average radiation dose to an organ per microcurie/day accumulated by a radionuclide in a source organ. The dosimetric data on photons are obtained by Monte Carlo type computer calculations on a non-homogeneous phantom having the general form of the human body. (U.S.)

  15. Patient and personnel dose measurements at selective coronarangiography

    International Nuclear Information System (INIS)

    Maripuu, E.

    1977-01-01

    During 1975 dose measurements were performed on patients and doctors at the thoraxradiologic department of the Caroline Hospital in Stockholm, Sweden. The doses were measured during angiography. Skin doses are listed in tables. Also the doses to the bone marrow was estimated. LiF-dosemeters were used for the measurements. Calibration of the dosemeters and errors in the measurements are discussed

  16. SU-E-J-110: Dosimetric Analysis of Respiratory Motion Based On Four-Dimensional Dose Accumulation in Liver Stereotactic Body Radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Kang, S; Kim, D; Kim, T; Kim, K; Cho, M; Shin, D; Suh, T [The Catholic University of Korea College of Medicine, Seoul (Korea, Republic of); Kim, S [Virginia Commonwealth University, Richmond, VA (United States); Park, S [Uijeongbu St.Mary’s Hospital, GyeongGi-Do (Korea, Republic of)

    2015-06-15

    Purpose: Respiratory motion in thoracic and abdominal region could lead to significant underdosing of target and increased dose to healthy tissues. The aim of this study is to evaluate the dosimetric effect of respiratory motion in conventional 3D dose by comparing 4D deformable dose in liver stereotactic body radiotherapy (SBRT). Methods: Five patients who had previously treated liver SBRT were included in this study. Four-dimensional computed tomography (4DCT) images with 10 phases for all patients were acquired on multi-slice CT scanner (Siemens, Somatom definition). Conventional 3D planning was performed using the average intensity projection (AIP) images. 4D dose accumulation was calculated by summation of dose distribution for all phase images of 4DCT using deformable image registration (DIR) . The target volume and normal organs dose were evaluated with the 4D dose and compared with those from 3D dose. And also, Index of achievement (IOA) which assesses the consistency between planned dose and prescription dose was used to compare target dose distribution between 3D and 4D dose. Results: Although the 3D dose calculation considered the moving target coverage, significant differences of various dosimetric parameters between 4D and 3D dose were observed in normal organs and PTV. The conventional 3D dose overestimated dose to PTV, however, there was no significant difference for GTV. The average difference of IOA which become ‘1’ in an ideal case was 3.2% in PTV. The average difference of liver and duodenum was 5% and 16% respectively. Conclusion: 4D dose accumulation which can provide dosimetric effect of respiratory motion has a possibility to predict the more accurate delivered dose to target and normal organs and improve treatment accuracy. This work was supported by the Radiation Technology R&D program (No. 2013M2A2A7043498) and the Mid-career Researcher Program (2014R1A2A1A10050270) through the National Research Foundation of Korea funded by the

  17. Implementation of Ray Safe i2 System for staff dose measuring in interventional radiology

    International Nuclear Information System (INIS)

    Gershan, Vesna; Atsovska, Violeta

    2013-01-01

    Interventional radiology procedures usually delivered the highest radiation dose to the patients as well as to medical personal. Beside another factors like patient size, fluoroscopy time, machine calibration etc., a good clinical practice has strong effects to staff and patient’s radiation dose. Materials and methods: In August 2012, a Ray Safe i2 system was installed in a private hospital in Skopje. The main purpose of this dosimetry system is to provide real time indication for the current exposure level of the medical personal. Knowing that, the staff has prerequisites to adjust their behavior to minimize unnecessary exposure like changing distance from exposed volume, C-ram angulations, field of view etc. and on this way to develop a good clinical practice. The Ray Safe i2 system is consisted by ten digital dosimeters, two dock stations, real time display, dose viewer and dose manager software. During interventional procedures, each involved staff wears dosimeter which measures and records X-Ray exposure every second and transfer the data wirelessly to the real time display. Color indication bars (green, yellow, red) represents the intensity of the currently received exposure, whereas green zone indicates < 0.2 mSv/h, yellow zone from 0.2 to 2 mSv/h and red zone indications from 2 to 20 mSv/h. Additionally, accumulated dose per individual is displayed next to the color indication bars. By using the software, information about personal dose history, such as annual dose, dose per particular session, hour, day or week, can be viewed and analyzed. Results: In this work it was found that staff accumulated doses were constantly increased over time, but reported number of procedures does not correspond to this tendency. Our assumption is that there is a misleading between reported number and actual performed procedures. Doctor1 received 55 times more dose than Doctor2 and Nurse1 received 11 to 3 times more dose than another Nurses. It was found a correlation of R2

  18. Skin dose measurement with MICROSPEC-2 trademark

    International Nuclear Information System (INIS)

    Hsu, H.H.

    1997-01-01

    For many years, the Eberline HP-260 trademark beta detectors were used for skin dose measurements at Los Alamos National Laboratory. This detector does not measure the beta spectrum and the skin dose can only be determined if the contaminating radioactive isotope is known. A new product MICROSPEC-2 trademark, has been developed which consists of a small portable computer with a multichannel analyzer and a beta probe consisting of a phoswich detector. The system measures the beta spectrum and automatically folds in the beta fluence-to-dose conversion function to yield the skin dose

  19. Simple DVH parameter addition as compared to deformable registration for bladder dose accumulation in cervix cancer brachytherapy

    DEFF Research Database (Denmark)

    Andersen, Else Stougård; Noe, Karsten Østergaaard; Sørensen, Thomas Sangild

    2013-01-01

    Background and purpose: Variations in organ position, shape, and volume cause uncertainties in dose assessment for brachytherapy (BT) in cervix cancer. The purpose of this study was to evaluate uncertainties associated with bladder dose accumulation based on DVH parameter addition (previously...... called "the worst case assumption") in fractionated BT. Materials and methods: Forty-seven patients treated for locally advanced cervical cancer were included. All patients received EBRT combined with two individually planned 3D image-guided adaptive BT fractions. D2 and D0.1 were estimated by DVH...

  20. Prediction of midline dose from entrance ad exit dose using OSLD measurements for total irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Chang Heon; Park, Jong Min; Park, So Yeon; Chun, Min Soo; Han, Ji Hye; Cho, Jin Dong; Kim, Jung In [Dept. of Radiation Oncology, Seoul National University Hospital, Seoul (Korea, Republic of)

    2017-06-15

    This study aims to predict the midline dose based on the entrance and exit doses from optically stimulated luminescence detector (OSLD) measurements for total body irradiation (TBI). For TBI treatment, beam data sets were measured for 6 MV and 15 MV beams. To evaluate the tissue lateral effect of various thicknesses, the midline dose and peak dose were measured using a solid water phantom (SWP) and ion chamber. The entrance and exit doses were measured using OSLDs. OSLDs were attached onto the central beam axis at the entrance and exit surfaces of the phantom. The predicted midline dose was evaluated as the sum of the entrance and exit doses by OSLD measurement. The ratio of the entrance dose to the exit dose was evaluated at various thicknesses. The ratio of the peak dose to the midline dose was 1.12 for a 30 cm thick SWP at both energies. When the patient thickness is greater than 30 cm, the 15 MV should be used to ensure dose homogeneity. The ratio of the entrance dose to the exit dose was less than 1.0 for thicknesses of less than 30 cm and 40 cm at 6 MV and 15 MV, respectively. Therefore, the predicted midline dose can be underestimated for thinner body. At 15 MV, the ratios were approximately 1.06 for a thickness of 50 cm. In cases where adult patients are treated with the 15 MV photon beam, it is possible for the predicted midline dose to be overestimated for parts of the body with a thickness of 50 cm or greater. The predicted midline dose and OSLD-measured midline dose depend on the phantom thickness. For in-vivo dosimetry of TBI, the measurement dose should be corrected in order to accurately predict the midline dose.

  1. Development of Real-Time Measurement of Effective Dose for High Dose Rate Neutron Fields

    International Nuclear Information System (INIS)

    Braby, L. A.; Reece, W. D.; Hsu, W. H.

    2003-01-01

    Studies of the effects of low doses of ionizing radiation require sources of radiation which are well characterized in terms of the dose and the quality of the radiation. One of the best measures of the quality of neutron irradiation is the dose mean lineal energy. At very low dose rates this can be determined by measuring individual energy deposition events, and calculating the dose mean of the event size. However, at the dose rates that are normally required for biology experiments, the individual events can not be separated by radiation detectors. However, the total energy deposited in a specified time interval can be measured. This total energy has a random variation which depends on the size of the individual events, so the dose mean lineal energy can be calculated from the variance of repeated measurements of the energy deposited in a fixed time. We have developed a specialized charge integration circuit for the measurement of the charge produced in a small ion chamber in typical neutron irradiation experiments. We have also developed 4.3 mm diameter ion chambers with both tissue equivalent and carbon walls for the purpose of measuring dose mean lineal energy due to all radiations and due to all radiations except neutrons, respectively. By adjusting the gas pressure in the ion chamber, it can be made to simulate tissue volumes from a few nanometers to a few millimeters in diameter. The charge is integrated for 0.1 seconds, and the resulting pulse height is recorded by a multi channel analyzer. The system has been used in a variety of photon and neutron radiation fields, and measured values of dose and dose mean lineal energy are consistent with values extrapolated from measurements made by other techniques at much lower dose rates. It is expected that this technique will prove to be much more reliable than extrapolations from measurements made at low dose rates because these low dose rate exposures generally do not accurately reproduce the attenuation and

  2. Calculation of midplane dose for total body irradiation from entrance and exit dose MOSFET measurements.

    Science.gov (United States)

    Satory, P R

    2012-03-01

    This work is the development of a MOSFET based surface in vivo dosimetry system for total body irradiation patients treated with bilateral extended SSD beams using PMMA missing tissue compensators adjacent to the patient. An empirical formula to calculate midplane dose from MOSFET measured entrance and exit doses has been derived. The dependency of surface dose on the air-gap between the spoiler and the surface was investigated by suspending a spoiler above a water phantom, and taking percentage depth dose measurements (PDD). Exit and entrances doses were measured with MOSFETs in conjunction with midplane doses measured with an ion chamber. The entrance and exit doses were combined using an exponential attenuation formula to give an estimate of midplane dose and were compared to the midplane ion chamber measurement for a range of phantom thicknesses. Having a maximum PDD at the surface simplifies the prediction of midplane dose, which is achieved by ensuring that the air gap between the compensator and the surface is less than 10 cm. The comparison of estimated midplane dose and measured midplane dose showed no dependence on phantom thickness and an average correction factor of 0.88 was found. If the missing tissue compensators are kept within 10 cm of the patient then MOSFET measurements of entrance and exit dose can predict the midplane dose for the patient.

  3. Problems in continuous dose rate measurement

    International Nuclear Information System (INIS)

    Yoshioka, Mitsuo

    1983-01-01

    The system of continuous dose rate measurement in Fukui Prefecture is described. A telemeter system was constructed in October, 1976, and it has been operated since 1977. Observation has been made at 11 observation stations in the Prefecture. In addition to the continuous measurement of dose rate by using NaI(T1)-DBM systems, the ionization chambers for high dose rate were installed, and also meteorological data have been collected. The detectors are covered with 1 mm thick aluminum designed so that the absorption of external radiation is kept as small as possible. To keep the environmental temperature of the detectors constant, constant temperature wind blow is made. With these consideration, the measurement of Xe-133 is possible, and the standard deviation of yearly dose is around 0.4 mR/Y. By measuring DBM transmission rate, the contribution of Xe-133, which comes from the exhaust pumps in power plants, can be detected. The problems of this system are as follows. First of all, the characteristics of the system must meet the purpose of dose monitoring. The system must detect the dose less than the target value to be achieved. The second is the selection of measuring systems to be set. The system is still not unified, and it is difficult to exchange data between different stations. Finally, the method of data analysis is not yet unified. Manuals or guide-books for this purpose are necessary for the mutual comparison of the data from the stations in different districts. (Kato, T.)

  4. Issues in the reconstruction of environmental doses on the basis of thermoluminescence measurements in the Techa riverside

    Science.gov (United States)

    Bougrov, N. G.; Goksu, H. Y.; Haskell, E.; Degteva, M. O.; Meckbach, R.; Jacob, P.; Neta, P. I. (Principal Investigator)

    1998-01-01

    The potential of thermoluminescence measurements of bricks from the contaminated area of the Techa river valley, Southern Urals, Russia, for reconstructing external exposures of affected population groups has been studied. Thermoluminescence dating of background samples was used to evaluate the age of old buildings available on the river banks. The anthropogenic gamma dose accrued in exposed samples is determined by subtracting the natural radiation background dose for the corresponding age from the accumulated dose measured by thermoluminescence. For a site in the upper Techa river region, where the levels of external exposures were extremely high, the depth-dose distribution in bricks and the dependence of accidental dose on the height of the sampling position were determined. For the same site, Monte Carlo simulations of radiation transport were performed for different source configurations corresponding to the situation before and after the construction of a reservoir on the river and evacuation of the population in 1956. A comparison of the results provides an understanding of the features of the measured depth-dose distributions and height dependencies in terms of the source configurations and shows that bricks from the higher sampling positions are likely to have accrued a larger fraction of anthropogenic dose from the time before the construction of the reservoir. The applicability of the thermoluminescent dosimetry method to environmental dose reconstruction in the middle Techa region, where the external exposure was relatively low, was also investigated.

  5. ''Nonisolated-sensor'' solid polystyrene absorbed dose measurements

    International Nuclear Information System (INIS)

    Zeitz, L.; Laughlin, J.S.

    1982-01-01

    A ''nonisolated-sensor'' solid polystyrene calorimeter was constructed to test the role of thermal diffusion in limiting the length of irradiation time during which temperature measurements with nonisolated sensors could be made sufficiently free of drift for determining dose with radiation fields such as gamma rays, x rays, and high-energy electrons. From measured ratios of dose at 5.0 and 0.5 cm in polystyrene and comparisons to dose measurements with a polystyrene parallel-plate (pancake) ion chamber, it was shown that thermal diffusion is sufficiently small in polystyrene to permit accurate measurements for irradiation periods of less than 20 min. Comparison of the absorbed dose measurements and depth dose ratios with pancake ion chambers and calorimeter showed, that within the precision and accuracy of the two measuring systems, there is close agreement. The nonisolated-sensor solid polystyrene calorimeter has the interesting features of (i) simplicity of construction, (ii) simplicity of operation without vacuum or feedback for temperature control, (iii) capability of simultaneous measurements at several depths and off-axis positions, (iv) the very small thermal defect correction with polystyrene, and (v) operation with the calorimeter in any orientation

  6. Nonisolated-sensor solid polystyrene absorbed dose measurements

    International Nuclear Information System (INIS)

    Zeitz, L.; Laughlin, J.S.

    1982-01-01

    A nonisolated-sensor solid polystyrene calorimeter was constructed to test the role of thermal diffusion in limiting the length of irradiation time during which temperature measurements with nonisolated sensors could be made sufficiently free of drift for determining dose with radiation fields such as gamma rays, x rays, and high-energy electrons. From measured ratios of dose at 5.0 and 0.5 cm in polystyrene and comparisons to dose measurements with a polystyrene parallel-plate (pancake) ion chamber, it was shown that thermal diffusion is sufficiently small in polystyrene to permit accurate measurements for irradiation periods of less than 20 min. Comparison of the absorbed dose measurements and depth dose ratios with pancake ion chambers and calorimeter showed, that within the precision and accuracy of the two measuring systems, there is close agreement. The nonisolated-sensor solid polystyrene calorimeter has the interesting features of (i) simplicity of construction, (ii) simplicity of operation without vacuum or feedback for temperature control, (iii) capability of simultaneous measurements at several depths and off-axis positions, (iv) the very small thermal defect correction with polystyrene, and (v) operation with the calorimeter in any orientation

  7. Radiation dose measurements

    International Nuclear Information System (INIS)

    1960-01-01

    About 200 scientists from 28 countries and 5 international organizations met at a symposium on radiation dosimetry held by the International Atomic Energy Agency in June 1960. The aim of the symposium was not so much the description of a large number of measuring instruments as a discussion of the methods used, with special emphasis on those problems which had become important in the context of recent developments, such as the measurement of mixed or very large doses

  8. Evaluation of linear array MOSFET detectors for in vivo dosimetry to measure rectal dose in HDR brachytherapy.

    Science.gov (United States)

    Haughey, Aisling; Coalter, George; Mugabe, Koki

    2011-09-01

    The study aimed to assess the suitability of linear array metal oxide semiconductor field effect transistor detectors (MOSFETs) as in vivo dosimeters to measure rectal dose in high dose rate brachytherapy treatments. The MOSFET arrays were calibrated with an Ir192 source and phantom measurements were performed to check agreement with the treatment planning system. The angular dependence, linearity and constancy of the detectors were evaluated. For in vivo measurements two sites were investigated, transperineal needle implants for prostate cancer and Fletcher suites for cervical cancer. The MOSFETs were inserted into the patients' rectum in theatre inside a modified flatus tube. The patients were then CT scanned for treatment planning. Measured rectal doses during treatment were compared with point dose measurements predicted by the TPS. The MOSFETs were found to require individual calibration factors. The calibration was found to drift by approximately 1% ±0.8 per 500 mV accumulated and varies with distance from source due to energy dependence. In vivo results for prostate patients found only 33% of measured doses agreed with the TPS within ±10%. For cervix cases 42% of measured doses agreed with the TPS within ±10%, however of those not agreeing variations of up to 70% were observed. One of the most limiting factors in this study was found to be the inability to prevent the MOSFET moving internally between the time of CT and treatment. Due to the many uncertainties associated with MOSFETs including calibration drift, angular dependence and the inability to know their exact position at the time of treatment, we consider them to be unsuitable for in vivo dosimetry in rectum for HDR brachytherapy.

  9. Evaluation of linear array MOSFET detectors for in vivo dosimetry to measure rectal dose in DHR brachytherapy

    International Nuclear Information System (INIS)

    Haughey, A.; Coalter, G.; Mugabe, K.

    2011-01-01

    Full text: The study aimed to assess the suitability of linear array metal oxide semiconductor field effect transistor detectors (MOSFETs) as in vivo dosimeters to measure rectal dose in high dose rate brachytherapy treatments. The MOSFET arrays were calibrated with an Ir192 source and phantom measurements were performed to check agreement with the treatment planning system. The angular dependence, linearity and constancy of the detectors were evaluated. For in vivo measurements two sites were investigated, transperineal needle implants for prostate cancer and Fletcher suites for cervical cancer. The MOSFETs were inserted into the patients' rectum in theatre inside a modified flatus tube. The patients were then CT scanned for treatment planning. Measured rectal doses during treatment were compared with point dose measurements predicted by the TPS. The MOSFETs were found to require individual calibration factors. The calibration was found to drift by approximately 1% ±0.8 per 500 mV accumulated and varies with distance from source due to energy dependence. In vivo results for prostate patients found only 33% of measured doses agreed with the TPS within ±1O%. For cervix cases 42% of measured doses agreed with the TPS within ± 10%, however of those not agreeing variations of up to 70% were observed. One of the most limiting factors in this study was found to be the inability to prevent the MOSFET moving internally between the time of CT and treatment. Due to the many uncertainties associated with MOSFETs including calibration drift, angular dependence and the inability to know their exact position at the time of treatment, we consider them to be unsuitable for in vivo dosimetry in rectum for HDR brachytherapy. (author)

  10. Development of Real-Time Measurement of Effective Dose for High Dose Rate Neutron Fields

    CERN Document Server

    Braby, L A; Reece, W D

    2003-01-01

    Studies of the effects of low doses of ionizing radiation require sources of radiation which are well characterized in terms of the dose and the quality of the radiation. One of the best measures of the quality of neutron irradiation is the dose mean lineal energy. At very low dose rates this can be determined by measuring individual energy deposition events, and calculating the dose mean of the event size. However, at the dose rates that are normally required for biology experiments, the individual events can not be separated by radiation detectors. However, the total energy deposited in a specified time interval can be measured. This total energy has a random variation which depends on the size of the individual events, so the dose mean lineal energy can be calculated from the variance of repeated measurements of the energy deposited in a fixed time. We have developed a specialized charge integration circuit for the measurement of the charge produced in a small ion chamber in typical neutron irradiation exp...

  11. Measurement of the neutron and gamma doses accumulated during commercial jet flights from Sydney to several major destinations in the northern and southern hemisphere

    International Nuclear Information System (INIS)

    Mukherjee, B.; Cross, P.; Alsop, R.

    2002-01-01

    As recommended by the ICRP, the European Union (EU) agreed to abide by mandatory monitoring of radiation doses to crew during civil aviation flights operated by the airlines of the EU member states. A large number of measured and theoretically predicted values for the in-flights radiation doses of northern hemisphere flight routes are available. On the other hand very few data have been published for the southern hemisphere. This paper will present the results of Australian domestic and international return flight routes originating from Sydney. The paper also presents results of trans-hemisphere air traffic routes. Neutron and gamma doses were measured using superheated bubble dosemeters and semiconductor detectors respectively. Based on our measurements a method is suggested whereby aircrew may share their personal radiation burden by flight crew hemisphere exchange. (author)

  12. Measurement of radiation dose in dental radiology

    International Nuclear Information System (INIS)

    Helmrot, E.; Carlsson, G. A.

    2005-01-01

    Patient dose audit is an important tool for quality control and it is important to have a well-defined and easy to use method for dose measurements. In dental radiology, the most commonly used dose parameters for the setting of diagnostic reference levels (DRLs) are the entrance surface air kerma (ESAK) for intraoral examinations and dose width product (DWP) for panoramic examinations. DWP is the air kerma at the front side of the secondary collimator integrated over the collimator width and an exposure cycle. ESAK or DWP is usually measured in the absence of the patient but with the same settings of tube voltage (kV), tube current (mA) and exposure time as with the patient present. Neither of these methods is easy to use, and, in addition, DWP is not a risk related quantity. A better method of monitoring patient dose would be to use a dose area product (DAP) meter for all types of dental examinations. In this study, measurements with a DAP meter are reported for intraoral and panoramic examinations. The DWP is also measured with a pencil ionisation chamber and the product of DWP and the height H (DWP x H) of the secondary collimator (measured using film) was compared to DAP. The results show that it is feasible to measure DAP using a DAP meter for both intraoral and panoramic examinations. The DAP is therefore recommended for the setting of DRLs. (authors)

  13. Dual Mode NOx Sensor: Measuring Both the Accumulated Amount and Instantaneous Level at Low Concentrations

    Directory of Open Access Journals (Sweden)

    Jaco H. Visser

    2012-03-01

    Full Text Available The accumulating-type (or integrating-type NOx sensor principle offers two operation modes to measure low levels of NOx: The direct signal gives the total amount dosed over a time interval and its derivative the instantaneous concentration. With a linear sensor response, no baseline drift, and both response times and recovery times in the range of the gas exchange time of the test bench (5 to 7 s, the integrating sensor is well suited to reliably detect low levels of NOx. Experimental results are presented demonstrating the sensor’s integrating properties for the total amount detection and its sensitivity to both NO and to NO2. We also show the correlation between the derivative of the sensor signal and the known gas concentration. The long-term detection of NOx in the sub-ppm range (e.g., for air quality measurements is discussed. Additionally, a self-adaption of the measurement range taking advantage of the temperature dependency of the sensitivity is addressed.

  14. Hand Dose in Nuclear Medicine Staff Members

    International Nuclear Information System (INIS)

    Taha, T.M.; Shahein, A.Y.; Hassan, R.

    2009-01-01

    Measurement of the hand dose during preparation and injection of radiopharmaceuticals is useful in the assessment of the extremity doses received by nuclear medicine personnel. Hand radiation doses to the occupational workers that handling 99m Tc-labeled compounds, 131 I for diagnostic in nuclear medicine were measured by thermoluminescence dosimetry. A convenient method is to use a TLD ring dosimeter for measuring doses of the diagnostic units of different nuclear medicine facilities . Their doses were reported in millisieverts that accumulated in 4 weeks. The radiation doses to the hands of nuclear medicine staff at the hospitals under study were measured. The maximum expected annual dose to the extremities appeared to be less than the annual limit (500 mSv/y) because all of these workers are on rotation and do not constantly handle radioactivity throughout the year

  15. Dose measurements in pulsed radiation fields with commercially available measuring components

    International Nuclear Information System (INIS)

    Friedrich, Sabrina; Hupe, Oliver

    2016-01-01

    Dose measurements in pulsed radiation fields with dosemeters using the counting technique are known to be inappropriate. Therefore, there is a demand for a portable device able to measure the dose in pulsed radiation fields. As a detector, ionisation chambers seem to be a good alternative. In particular, using a secondary standard ionisation chamber in combination with a reliable charge-measuring system would be a good solution. The Physikalisch-Technische Bundesanstalt (PTB) uses secondary standard ionisation chambers in combination with PTB-made measuring electronics for dose measurements at its reference fields. However, for general use, this equipment is too complex. For measurements on-site, a mobile special electronic system [Hupe, O. and Ankerhold, U. Determination of ambient and personal dose equivalent for personnel and cargo security screening. Radiat. Prot. Dosim. 121(4), 429-437 (2006)] has been used successfully. Still, for general use, there is a need for a much simpler but a just as good solution. A measuring instrument with very good energy dependence for H*(10) is the secondary standard ionisation chamber HS01. An easy-to-use and commercially available electrometer for measuring the generated charges is the UNIDOS by PTW Freiburg. Depending on the expected dose values, the ionisation chamber used can be selected. In addition, measurements have been performed by using commercially available area dosemeters, e.g. the Mini SmartION 2120S by Thermo Scientific, using an ionisation chamber and the Szintomat 6134 A/H by Automess, using a scintillation detector. (authors)

  16. SU-E-I-10: Automatic Monitoring of Accumulated Dose Indices From DICOM RDSR to Improve Radiation Safety in X-Ray Angiography

    International Nuclear Information System (INIS)

    Omar, A; Bujila, R; Nowik, P; Karambatsakidou, A

    2014-01-01

    Purpose: To investigate the potential benefits of automatic monitoring of accumulated patient and staff dose indicators, i.e., CAK and KAP, from DICOM Radiation Dose Structured Reports (RDSR) in x-ray angiography (XA). Methods: Recently RDSR has enabled the convenient aggregation of dose indices and technique parameters for XA procedures. The information contained in RDSR objects for three XA systems, dedicated to different types of clinical procedures, has been collected and aggregated in a database for over one year using a system developed with open-source software at the Karolinska University Hospital. Patient weight was complemented to the RDSR data via an interface with the Hospital Information System (HIS). Results: The linearly approximated trend in KAP over a time period of a year for cerebrovascular, pelvic/peripheral vascular, and cardiovascular procedures showed a decrease of 12%, 20%, and 14%, respectively. The decrease was mainly due to hardware/software upgrades and new low-dose imaging protocols, and partially due to ongoing systematic radiation safety education of the clinical staff. The CAK was in excess of 3 Gy for 15 procedures, and exceeded 5 Gy for 3 procedures. The dose indices have also shown a significant dependence on patient weight for cardiovascular and pelvic/peripheral vascular procedures; a 10 kg shift in mean patient weight can result in a dose index increase of 25%. Conclusion: Automatic monitoring of accumulated dose indices can be utilized to notify the clinical staff and medical physicists when the dose index has exceeded a predetermined action level. This allows for convenient and systematic follow-up of patients in risk of developing deterministic skin injuries. Furthermore, trend analyses of dose indices over time is a valuable resource for the identification of potential positive or negative effects (dose increase/decrease) from changes in hardware, software, and clinical work habits

  17. SU-E-I-10: Automatic Monitoring of Accumulated Dose Indices From DICOM RDSR to Improve Radiation Safety in X-Ray Angiography

    Energy Technology Data Exchange (ETDEWEB)

    Omar, A; Bujila, R; Nowik, P; Karambatsakidou, A [Karolinska University Hospital, Stockholm (Sweden)

    2014-06-01

    Purpose: To investigate the potential benefits of automatic monitoring of accumulated patient and staff dose indicators, i.e., CAK and KAP, from DICOM Radiation Dose Structured Reports (RDSR) in x-ray angiography (XA). Methods: Recently RDSR has enabled the convenient aggregation of dose indices and technique parameters for XA procedures. The information contained in RDSR objects for three XA systems, dedicated to different types of clinical procedures, has been collected and aggregated in a database for over one year using a system developed with open-source software at the Karolinska University Hospital. Patient weight was complemented to the RDSR data via an interface with the Hospital Information System (HIS). Results: The linearly approximated trend in KAP over a time period of a year for cerebrovascular, pelvic/peripheral vascular, and cardiovascular procedures showed a decrease of 12%, 20%, and 14%, respectively. The decrease was mainly due to hardware/software upgrades and new low-dose imaging protocols, and partially due to ongoing systematic radiation safety education of the clinical staff. The CAK was in excess of 3 Gy for 15 procedures, and exceeded 5 Gy for 3 procedures. The dose indices have also shown a significant dependence on patient weight for cardiovascular and pelvic/peripheral vascular procedures; a 10 kg shift in mean patient weight can result in a dose index increase of 25%. Conclusion: Automatic monitoring of accumulated dose indices can be utilized to notify the clinical staff and medical physicists when the dose index has exceeded a predetermined action level. This allows for convenient and systematic follow-up of patients in risk of developing deterministic skin injuries. Furthermore, trend analyses of dose indices over time is a valuable resource for the identification of potential positive or negative effects (dose increase/decrease) from changes in hardware, software, and clinical work habits.

  18. Patient dose measurement and dose reduction in chest radiography

    Directory of Open Access Journals (Sweden)

    Milatović Aleksandra A.

    2014-01-01

    Full Text Available Investigations presented in this paper represent the first estimation of patient doses in chest radiography in Montenegro. In the initial stage of our study, we measured the entrance surface air kerma and kerma area product for chest radiography in five major health institutions in the country. A total of 214 patients were observed. We reported the mean value, minimum and third quartile values, as well as maximum values of surface air kerma and kerma area product of patient doses. In the second stage, the possibilities for dose reduction were investigated. Mean kerma area product values were 0.8 ± 0.5 Gycm2 for the posterior-anterior projection and 1.6 ± 0.9 Gycm2 for the lateral projection. The max/min ratio for the entrance surface air kerma was found to be 53 for the posterior-anterior projection and 88 for the lateral projection. Comparing the results obtained in Montenegro with results from other countries, we concluded that patient doses in our medical centres are significantly higher. Changes in exposure parameters and increased filtration contributed to a dose reduction of up to 36% for posterior-anterior chest examinations. The variability of the estimated dose values points to a significant space for dose reduction throughout the process of radiological practice optimisation.

  19. Measuring pacemaker dose: A clinical perspective

    Energy Technology Data Exchange (ETDEWEB)

    Studenski, Matthew T., E-mail: matthew.studenski@jeffersonhospital.org [Department of Radiation Oncology at the Jefferson Medical College and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (United States); Xiao Ying; Harrison, Amy S. [Department of Radiation Oncology at the Jefferson Medical College and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (United States)

    2012-07-01

    Recently in our clinic, we have seen an increased number of patients presenting with pacemakers and defibrillators. Precautions are taken to develop a treatment plan that minimizes the dose to the pacemaker because of the adverse effects of radiation on the electronics. Here we analyze different dosimeters to determine which is the most accurate in measuring pacemaker or defibrillator dose while at the same time not requiring a significant investment in time to maintain an efficient workflow in the clinic. The dosimeters analyzed here were ion chambers, diodes, metal-oxide-semiconductor field effect transistor (MOSFETs), and optically stimulated luminescence (OSL) dosimeters. A simple phantom was used to quantify the angular and energy dependence of each dosimeter. Next, 8 patients plans were delivered to a Rando phantom with all the dosimeters located where the pacemaker would be, and the measurements were compared with the predicted dose. A cone beam computed tomography (CBCT) image was obtained to determine the dosimeter response in the kilovoltage energy range. In terms of the angular and energy dependence of the dosimeters, the ion chamber and diode were the most stable. For the clinical cases, all the dosimeters match relatively well with the predicted dose, although the ideal dosimeter to use is case dependent. The dosimeters, especially the MOSFETS, tend to be less accurate for the plans, with many lateral beams. Because of their efficiency, we recommend using a MOSFET or a diode to measure the dose. If a discrepancy is observed between the measured and expected dose (especially when the pacemaker to field edge is <10 cm), we recommend analyzing the treatment plan to see whether there are many lateral beams. Follow-up with another dosimeter rather than repeating multiple times with the same type of dosimeter. All dosimeters should be placed after the CBCT has been acquired.

  20. Low Doses of Cadmium Chloride and Methallothionein-1-Bound Cadmium Display Different Accumulation Kinetics and Induce Different Genes in Cells of the Human Nephron

    Directory of Open Access Journals (Sweden)

    Dana Cucu

    2011-08-01

    Full Text Available Background/Aims: The present study was conducted to investigate the renal tubular handling of inorganic cadmium (Cd2+ by exposing primary human tubular cell cultures to physiologically relevant doses of cadmium chloride (CdCl2. Furthermore, the cellular accumulation of Cd2+ was compared to that of metallothionein-1-bound Cd (Cd7MT-1. Finally, this study aimed to investigate the effect of the accumulation of Cd (both Cd2+ and Cd7MT-1 in renal cells on the expression of genes relevant to nephrotoxic processes. Methods: Cd concentration was measured using atomic absorption spectrometry. mRNA expression was evaluated by quantitative real-time RT-PCR. Results: Cd2+ accumulated into human tubular cells in a concentration- and time-dependent way. Furthermore, cellular accumulation of Cd2+ was different from the cellular accumulation of Cd7MT-1, indicative for different uptake routes. Finally, mRNA expression of the genes encoding the anti-oxidative proteins metallothionein-1 (MT-1 and heme-oxygenase-1 (HO-1 as well as the pro-apoptotic Bcl-2-associated X protein (Bax were upregulated by CdCl2 and not by Cd7MT1. Conclusion: In the presence of physiologically relevant Cd concentrations, tubular accumulation of the element in its inorganic form is different from that of Cd7MT-1. Furthermore, the tubular accumulation of inorganic Cd induces mRNA expression of genes of which the protein products may play a role in Cd-associated renal toxicity.

  1. Out-of-field dose measurements in radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Kaderka, Robert

    2011-07-13

    This thesis describes the results from measurements of the out-of-field dose in radiotherapy. The dose outside the treatment volume has been determined in a water phantom and an anthropomorphic phantom. Measurements were performed with linac photons, passively delivered protons, scanned protons, passively delivered carbon ions as well as scanned carbon ions. It was found that the use of charged particles for radiotherapy reduces the out-of-field dose by up to three orders of magnitude compared to conventional radiotherapy with photons.

  2. Skin Dose Equivalent Measurement from Neutron-Deficient Isotopes

    International Nuclear Information System (INIS)

    Hsu, Hsiao-Hua; Costigan, Steve A.; Romero, Leonard L.; Whicker, Jeffrey J.

    1997-12-01

    Neutron-deficient-isotopes decay via positron emission and/or electron capture often followed by x-ray, gamma-ray, and 0.511 MeV photons from positron annihilation. For cases of significant area and/or personnel contamination with these isotopes, determination of skin dose equivalent (SDE) is required by 10CFR835. For assessment of SDE, we evaluated the MICROSPEC-2(TM) system manufactured by Bubble Technology Industries of Canada which uses three different probes for dose measurement. We used two probes: (1) the X-probe which measures lower energy (4 - 120 keV) photon energy distributions and determines deep dose equivalent, SDE and dose equivalent to eyes, and (2) the B-probe which measures electron (positron) energy distributions, and determines skin dose equivalent. Also, the measured photon and beta spectra can be used to identify radioactive isotopes in the contaminated area. Measurements with several neutron-deficient sources showed that this system provided reasonably accurate SDE rate measurements when compared with calculated benchmark SDE rates with an average percent difference of 40%. Variations were expected because of differences between the assumed geometries used by MlCROSPEC-2 and the calculations when compared to the measurement conditions

  3. Measurement of spatial dose distribution for evaluation operator dose during nero-interventional procedures

    International Nuclear Information System (INIS)

    Han, Su Chul; Hong, Dong Hee

    2016-01-01

    The spatial dose distribution was measured with ionization chamber as preliminary study to evaluate operator dose and to study dose reduction during neuro-interventional procedures. The zone of operators was divided into four area (45, 135, 225, and 315 degree).We supposed that operator exist on the four area and indicated location of critical organs(eyes, breast, gonad). The spatial doses were measured depending on distance( 80, 100, 120, and 140 cm) and location of critical organs. The spatial doses of area of 225 degree were 114.5 mR/h (eyes location), 143.1 mR/h (breast location) and 147 mR/h (gonad location) in 80 cm. When changed location of x-ray generator, spatial dose increased in 18.1±10.5%, averagely. We certified spatial dose in the operator locations, Using the results of this study, It is feasible to protect operator from radiation in neuro-interventional procedures

  4. Measurement of spatial dose distribution for evaluation operator dose during nero-interventional procedures

    Energy Technology Data Exchange (ETDEWEB)

    Han, Su Chul [Division of Medical Radiation Equipment, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Hong, Dong Hee [Dept. of Radiology Science, Far East University, Eumseong (Korea, Republic of)

    2016-09-15

    The spatial dose distribution was measured with ionization chamber as preliminary study to evaluate operator dose and to study dose reduction during neuro-interventional procedures. The zone of operators was divided into four area (45, 135, 225, and 315 degree).We supposed that operator exist on the four area and indicated location of critical organs(eyes, breast, gonad). The spatial doses were measured depending on distance( 80, 100, 120, and 140 cm) and location of critical organs. The spatial doses of area of 225 degree were 114.5 mR/h (eyes location), 143.1 mR/h (breast location) and 147 mR/h (gonad location) in 80 cm. When changed location of x-ray generator, spatial dose increased in 18.1±10.5%, averagely. We certified spatial dose in the operator locations, Using the results of this study, It is feasible to protect operator from radiation in neuro-interventional procedures.

  5. Measurement of placental blood flow by the sup(113m)In accumulation method

    International Nuclear Information System (INIS)

    Olkkonen, H.; Suonio, S.

    1976-01-01

    The present work introduces the use of isotope In-113m in the assessment of placental blood flow. It is almost completely bound to plasma transferrin. Owing to this and its short half-life, In-113m introduces considerably slighter radiation dose to the fetus than Tc-99m. A typical tracer appearance curve is given and the In accumulation index is calculated. (M.S.)

  6. Thermoluminescent dosimeters for low dose X-ray measurements

    International Nuclear Information System (INIS)

    Del Sol Fernández, S.; García-Salcedo, R.; Sánchez-Guzmán, D.; Ramírez-Rodríguez, G.; Gaona, E.; León-Alfaro, M.A. de; Rivera-Montalvo, T.

    2016-01-01

    The response of TLD-100, CaSO_4:Dy and LiF:Mg,Cu,P for a range of X-ray low dose was measured. For calibration, the TLDs were arranged at the center of the X-ray field. The dose output of the X-ray machine was determined using an ACCU-Gold. All dosimeters were exposed at the available air kerma values of 14.69 mGy within a field 10×10 cm"2 at 80 cm of SSD. Results of LiF:Mg,Cu,P X-ray irradiated showed 4.8 times higher sensitivity than TLD-100. Meanwhile, TL response of CaSO_4:Dy exposed at the same dose was 5.6 time higher than TLD-100. Experimental results show for low dose X-ray measurements a better linearity for LiF:Mg,Cu,P compared with that of TLD-100. CaSO_4:Dy showed a linearity from 0.1 to 60 mGy - Highlights: • Low dose X-ray doses for personal dosimetry were measured. • Radiation dose (µGy ) for environmental dosimetry were determined. • Scattering radiation dose were measured by TLDs. • Linearity of pair TLD system was successful in the range of microgray. • Pair TLDs composed by CaSO_4:Dy and by LiF:Mg,Cu,P. is suggested for clinical dosimetry.

  7. measurement of high dose radiation using yellow perspex dosimeter

    International Nuclear Information System (INIS)

    Thamrin, M Thoyib; Sofyan, Hasnel

    1996-01-01

    Measurement of high dose radiation using yellow perspex dosemeter has been carried out. Dose range used was between 0.1 to 3.0 kGy. Measurement of dose rate against Fricke dosemeter as a standard dose meter From the irradiation of Fricke dosemeter with time variation of 3,6,9,12,15 and 18 minute, it was obtained average dose rate of 955.57 Gy/hour, linear equation of dose was Y= 2.333+15.776 X with its correlation factor r = 0.9999. Measurement result using yellow perspex show that correlation between net optical density and radiation dose was not linear with its equation was ODc exp. [Bo + In(dose).Bi] Value of Bo = -0.215 and Bi=0.5020. From the experiment it was suggested that routine dosimeter (yellow perspex) should be calibrated formerly against standard dosemeters

  8. In vivo measurement of urethral dose profiles

    International Nuclear Information System (INIS)

    Toye, W.C.; Royal Melbourne Institute of Technology,; Duchesne, G.M.; Das, K.R.; Cee, A.; Mameghan, H.; Johnston, P.N.

    2001-01-01

    Full text: Quality assurance becomes a critical requirement when radiographs are routinely used in planning of treatments. In HDR prostate brachytherapy, the surrounding organs at risk of complications are the bladder and the rectum. However, of particular concern is the urethra that runs centrally through the prostate gland, as an unavoidably high dose can occur in the central region in order to achieve a minimum peripheral dose to a small target volume. Although high urethral doses have previously been related to increased urinary symptoms, some recent studies have not found such a correlation. The aim of this study was firstly, to identify dosimetric indicators of urethral morbidity following HDR prostate brachytherapy (4F x of 5.0 Gy), and secondly, to test the validity of calculated dose values. The in vivo measurements utilised a TLD (LiF:Mg,Ti) train formed by loading eight TLD rods alternating with 1,0 cm brass spacers into a fine plastic flexible tube. The length and diameter of plastic tubing was approximately 45cm and 0.15cm respectively, while the train length was 11.8 cm from the tip of the tube. The TLD train was placed into the central lumen of an 18 F three-way urethral catheter prior to its insertion. Significant urinary morbidity was defined prospectively as a score of a total of 3 or more points for severity from 5 symptoms categories. The five symptoms evaluated were hesitancy, frequency/nocturia, dysuria, haematuria and incontinence. The introduction of in vivo measurements to enhance the existing dosimetric analysis may be required to fully test the quantitative relationships (e.g. dose-volume ratios). Placement of TLDs within the urethra results in measurements whose accuracy is unaffected by internal organ motion as the hollow urethra must move with the prostate. The dose recorded by the TLDs is determined independently of the predictive algorithm used by the treatment planning system, and prostate location errors (e.g. due to image

  9. Passive Rn dose meters - measuring methods appropriate for large measurement series

    International Nuclear Information System (INIS)

    Urban, M.; Kiefer, H.

    1985-01-01

    Passive integrating measuring methods can be classified in several groups by their functioning principle, e.g. spray chambers or open chambers with nuclear trace detectors or TL detectors, open detectors, activated carbon dose meters with or without TL detectors. According to the functioning principle, only radon or radon and fission products can be detected. The lecture gives a survey of the present state of development of passive Rn dose meters. By the example of the Ra dose meter developed at Karlsruhe which was used in inquiry measurements carried out in Germany, Switzerland, the Netherlands, Belgium and Austria, etching technology, estimation of measuring uncertainties, reproducibility and fading behaviour shall be discussed. (orig./HP) [de

  10. Measurement of the equivalent dose in quartz using a regenerative-dose single-aliquot protocol

    International Nuclear Information System (INIS)

    Murray, A.S.; Roberts, R.G.

    1998-01-01

    The principles behind a regenerative-dose single-aliquot protocol are outlined. It is shown for three laboratory-bleached Australian sedimentary quartz samples that the relative change in sensitivity of the optically stimulated luminescence (OSL) during a repeated measurement cycle (consisting of a dose followed by a 10 s preheat at a given temperature and then a 100 s exposure to blue/green light at 125 deg. C) is very similar to that of the 110 deg. C thermoluminescence (TL) peak measured during the preheat cycle. The absolute change in the TL sensitivity with preheat temperature is different for samples containing a natural or a regenerative dose. Furthermore, the absolute change in sensitivity in both the OSL and TL signals is non-linear with regeneration cycle, but the relative change in the OSL signal compared to the following 110 deg. C TL measurement is well approximated by a straight line. Both signals are thought to use the same luminescence centres, and so some common behaviour is not unexpected. A new regenerative-dose protocol is presented which makes use of this linear relationship to correct for sensitivity changes with regeneration cycle, and requires only one aliquot for the estimation of the equivalent dose (D e ). The protocol has been applied to quartz from nine Australian sites. To illustrate the value of the regenerative-dose single-aliquot approach, the apparent values of D e for 13 samples, containing doses of between 0.01 and 100 Gy, have been measured at various preheat temperatures of between 160 and 300 deg. C, using a single aliquot for each D e measurement. Excellent agreement is found between these single-aliquot estimates of D e and those obtained from additive-dose multiple-aliquot and single-aliquot protocols, over the entire dose range

  11. Transverse beam stability measurement and analysis for the SNS accumulator ring

    Energy Technology Data Exchange (ETDEWEB)

    Xie, Zaipeng [University of Wisconsin-Madison, Madison, WI 53706-1691 (United States); Deibele, Craig, E-mail: deibele@ornl.gov [Oak Ridge National Laboratory, PO BOX 2008 MS6483, Oak Ridge, TN 37831-6461 (United States); Schulte, Michael J.; Hu, Yu-Hen [University of Wisconsin-Madison, Madison, WI 53706-1691 (United States)

    2015-07-11

    A field-programmable gate array (FPGA)-based transverse feedback damper system was implemented in the Spallation Neutron Source (SNS) accumulator ring with the intention to stabilize the electron–proton (e–p) instability in the frequency range of 1–300 MHz. The transverse feedback damper could also be used as a diagnostic tool by measuring the beam transfer function (BTF). An analysis of the BTF measurements provides the stability diagram for the production beam at SNS. This paper describes the feedback damper system and its setup as the BTF diagnostic tool. Experimental BTF results are presented and beam stability is analyzed by use of the BTF measurements for the SNS accumulator ring.

  12. Transverse beam stability measurement and analysis for the SNS accumulator ring

    International Nuclear Information System (INIS)

    Xie, Zaipeng; Deibele, Craig; Schulte, Michael J.; Hu, Yu-Hen

    2015-01-01

    A field-programmable gate array (FPGA)-based transverse feedback damper system was implemented in the Spallation Neutron Source (SNS) accumulator ring with the intention to stabilize the electron–proton (e–p) instability in the frequency range of 1–300 MHz. The transverse feedback damper could also be used as a diagnostic tool by measuring the beam transfer function (BTF). An analysis of the BTF measurements provides the stability diagram for the production beam at SNS. This paper describes the feedback damper system and its setup as the BTF diagnostic tool. Experimental BTF results are presented and beam stability is analyzed by use of the BTF measurements for the SNS accumulator ring

  13. Dose measurement method suitable for management of food irradiation

    International Nuclear Information System (INIS)

    Tanaka, Ryuichi

    1990-01-01

    The report describes major features of dose measurement performed for the management of food irradiation processes, and dose measuring methods suitable for this purpose, and outlines some activities for establishing international standards for dose measurement. Traceability studies made recently are also reviewed. Compared with the sterilization of medical materials, food irradiation is different in some major points from a viewpoint of dose measurement: foods can undergo significant changes in bulk density, depending on its properties, during irradiation, and the variation in the uniformity of bulk density can be large within an irradiation unit and among different units. An accurate dosimeter and well-established traceability are essential for food irradiation control, and basically a dosimeter should be high in reproducibility and stable in dose response, and should be easy to readjust for eliminating systematic errors. A new type of dosimeter was developed recently, in which ESR is used to measure the free radicals generated by radiations in crystals of alanine, an amino acid. Standardization of large dose measurement procedures has been carried out by committee E10 set up under ASTM. (N.K.)

  14. Dose measurements in controlled area of TRIGA IPR-R1 reactor

    International Nuclear Information System (INIS)

    Alvarenga, F.L.; Junior, F.M.

    2005-01-01

    The workers doses in exposure areas to the radiation are so important for a Radioprotection Quality Program, as well as to guarantee the workers safety. For that it is necessary to raise the doses in the radiation areas, to obtain the accumulated dose in certain procedures for detailed studies. Several risings were accomplished to obtain the radiation levels in the areas where the workers are exposed due the operation of a research nuclear reactor and in the radioisotopes manipulation laboratories of a nuclear institute. The radiation levels and doses can be observed through graphs in the dependences of the Controlled Area 1 (AC-1) and the Reactor Laboratory. Those limits are in according of the CNEN-NE-3.01 work limits rules. The conclusion of the work allowed to demonstrate that the Laboratory of the Reactor and AC-1, have booth an effective radiological program with efficient operational practices that contributes with low doses to the workers

  15. Physical requirements for measurement of radiation dose and their relationship to personnel dose meter design and use

    International Nuclear Information System (INIS)

    Chabot, G.E. Jr.; Jimenez, M.A.; Skrable, K.W.

    1978-01-01

    This paper stems from the concerns of the authors with both the design of current personnel dose meters and the interpretation of dose information from them in light of the actual physical requirements to measure dose. These concerns have been reinforced and extended following a comparative study of the responses of particular TLD and film systems and as the result of a recent national survey on personnel dosimetry conducted by the authors. Among the major points discussed are the systems available for penetrating and shallow dose assessment, dose meter calibration, the measurement and interpretation of skin dose, and the deficiencies of neutron albedo dose meters for routine personnel use. Calibration considerations address the questions of whether or not a phantom should be used and the difference in interpretation of responses with and without a phantom; the relationship between calculated and measured doses; and electronic equilibrium considerations in the measurement of photon doses. Matters of importance in relation to skin dose measurement include techniques in use to interpret skin dose from dose meter response; the appropriateness of evaluation of the surface dose to the live skin layer versus the average dose to the live skin layer and the limitations and requirements on dose meter design with respect to the dose being evaluated; and the significance of dose meter response in relationship to currently used beta calibration standards. Regarding the use of TLD albedo type neutron dose meters currently available, considerations are extended to the strong energy spectral dependence of the dose meter response and the possibility of making significant over or underestimations of neutron dose equivalent, depending on the calibration techniques used and the spectral quality encountered. (author)

  16. Phantoms for IMRT dose distribution measurement and treatment verification

    International Nuclear Information System (INIS)

    Low, Daniel A.; Gerber, Russell L.; Mutic, Sasa; Purdy, James A.

    1998-01-01

    Background: The verification of intensity-modulated radiation therapy (IMRT) patient treatment dose distributions is currently based on custom-built or modified dose measurement phantoms. The only commercially available IMRT treatment planning and delivery system (Peacock, NOMOS Corp.) is supplied with a film phantom that allows accurate spatial localization of the dose distribution using radiographic film. However, measurements using other dosimeters are necessary for the thorough verification of IMRT. Methods: We have developed a phantom to enable dose measurements using a cylindrical ionization chamber and the localization of prescription isodose curves using a matrix of thermoluminescent dosimetry (TLD) chips. The external phantom cross-section is identical to that of the commercial phantom, to allow direct comparisons of measurements. A supplementary phantom has been fabricated to verify the IMRT dose distributions for pelvis treatments. Results: To date, this phantom has been used for the verification of IMRT dose distributions for head and neck and prostate cancer treatments. Designs are also presented for a phantom insert to be used with polymerizing gels (e.g., BANG-2) to obtain volumetric dose distribution measurements. Conclusion: The phantoms have proven useful in the quantitative evaluation of IMRT treatments

  17. Sequential measurements of spectrum and dose for cosmic-ray neutrons on the ground

    International Nuclear Information System (INIS)

    Hirabayashi, N.; Nunomiya, T.; Suzuki, H.; Nakamura, T.

    2002-01-01

    The earth is continually bathed in high-energy particles that come from outside the solar system, known as galactic cosmic rays. When these particles penetrate the magnetic fields of the solar system and the Earth and reach the Earth's atmosphere, they collide with atomic nuclei in air and secondary cosmic rays of every kind. On the other hand, levels of accumulation of the semiconductor increase recently, and the soft error that the cosmic-ray neutrons cause has been regarded as questionable. There have been long-term measurements of cosmic-ray neutron fluence at several places in the world, but no systematic study on cosmic-ray neutron spectrum measurements. This study aimed to measure the cosmic-ray neutron spectrum and dose on the ground during the solar maximum period of 2000 to 2002. Measurements have been continuing in a cabin of Tohoku University Kawauchi campus, by using five multi-moderator spectrometers (Bonner sphere), 12.7 cm diam by 12.7 cm long NE213 scintillator, and rem counter. The Bonner sphere uses a 5.08 cm diam spherical 3 He gas proportional counter and the rem counter uses a 12.7 cm diam 3 He gas counter. The neutron spectra were obtained by unfolding from the count rates measured with the Bonner sphere using the SAND code and the pulse height spectra measured with the NE213 scintillator using the FORIST code . The cosmic- ray neutron spectrum and ambient dose rates have been measured sequentially from April 2001. Furthermore, the correlation between ambient dose rate and the atmospheric pressure was investigated with a barometer. We are also very much interested in the variation of neutron spectrum following big solar flares. From the sequential measurements, we found that the cosmic-ray neutron spectrum has two peaks at around 1 MeV and at around 100 MeV, and the higher energy peak increases with a big solar flare

  18. Radiation dose measurement in gastrointestinal studies

    International Nuclear Information System (INIS)

    Sulieman, A.; Elzaki, M.; Kappas, C.; Theodorou, K.

    2011-01-01

    Barium studies investigations (barium swallow, barium meal and barium enema) are the basic routine radiological examination, where barium sulphate suspension is introduced to enhance image contrast of gastrointestinal tracts. The aim of this study was to quantify the patients' radiation doses during barium studies and to estimate the organ equivalent dose and effective dose with those procedures. A total of 33 investigations of barium studies were measured by using thermoluminescence dosemeters. The result showed that the patient entrance surface doses were 12.6±10, 44.5±49 and 35.7±50 mGy for barium swallow, barium meal, follow through and enema, respectively. Effective doses were 0.2, 0.35 and 1.4 mSv per procedure for barium swallow, meal and enema respectively. Radiation doses were comparable with the previous studies. A written protocol for each procedure will reduce the inter-operator variations and will help to reduce unnecessary exposure. (authors)

  19. Measurement of gamma radiation doses in nuclear power plant environment

    International Nuclear Information System (INIS)

    Bochvar, I.A.; Keirim-Markus, I.B.; Sergeeva, N.A.

    1976-01-01

    Considered are the problems of measuring gamma radiation dose values and the dose distribution in the nuclear power plant area with the aim of estimating the extent of their effect on the population. Presented are the dosimeters applied, their distribution throughout the controlled area, time of measurement. The distribution of gamma radiation doses over the controlled area and the dose alteration with the increase of the distance from the release source are shown. The results of measurements are investigated. The conclusion is made that operating nuclear power plants do not cause any increase in the gamma radiation dose over the area. Recommendations for clarifying the techniques for using dose-meters and decreasing measurement errors are given [ru

  20. Measured dose to ovaries and testes from Hodgkin's fields and determination of genetically significant dose

    International Nuclear Information System (INIS)

    Niroomand-Rad, A.; Cumberlin, R.

    1993-01-01

    The purpose of this study was to determine the genetically significant dose from therapeutic radiation exposure with Hodgkin's fields by estimating the doses to ovaries and testes. Phantom measurements were performed to verify estimated doses to ovaries and testes from Hodgkin's fields. Thermoluminescent LiF dosimeters (TLD-100) of 1 x 3 x 3 mm 3 dimensions were embedded in phantoms and exposed to standard mantle and paraaortic fields using Co-60, 4 MV, 6 MV, and 10 MV photon beams. The results show that measured doses to ovaries and testes are about two to five times higher than the corresponding graphically estimated doses for Co-60 and 4 MVX photon beams as depicted in ICRP publication 44. In addition, the measured doses to ovaries and testes are about 30% to 65% lower for 10 MV photon beams than for their corresponding Co-60 photon beams. The genetically significant dose from Hodgkin's treatment (less than 0.01 mSv) adds about 4% to the genetically significant dose contribution to medical procedures and adds less than 1% to the genetically significant dose from all sources. Therefore, the consequence to society is considered to be very small. The consequences for the individual patient are, likewise, small. 28 refs., 3 figs., 5 tabs

  1. Radiation Dose Measurement Using Chemical Dosimeters

    International Nuclear Information System (INIS)

    Lee, Min Sun; Kim, Eun Hee; Kim, Yu Ri; Han, Bum Soo

    2010-01-01

    The radiation dose can be estimated in various ways. Dose estimates can be obtained by either experiment or theoretical analysis. In experiments, radiation impact is assessed by measuring any change caused by energy deposition to the exposed matter, in terms of energy state (physical change), chemical production (chemical change) or biological abnormality (biological change). The chemical dosimetry is based on the implication that the energy deposited to the matter can be inferred from the consequential change in chemical production. The chemical dosimetry usually works on the sample that is an aqueous solution, a biological matter, or an organic substance. In this study, we estimated absorbed doses by quantitating chemical changes in matter caused by radiation exposure. Two different chemical dosimeters, Fricke and ECB (Ethanol-Chlorobenzene) dosimeter, were compared in several features including efficacy as dose indicator and effective dose range

  2. Studying and measuring the gamma radiation doses in Homs city

    International Nuclear Information System (INIS)

    Sofaan, A. H.

    2001-01-01

    The gamma radiation dose was measured in Homs city by using many portable dosimeters (electronic dosimeter and Geiger-Muller). The measurements were carried out in the indoor and outdoor buildings, for different time period, through one year (1999-2000). High purity germanium detector with low back ground radiation (HpGe) was used to determine radiation element contained in some building and the surrounding soil. The statistical analysis laws were applied to make sure that the measured dose distribution around average value is normal distribution. The measurement indicates that the gamma indoor dose varies from 312μSv/y to 511μSv/y, with the average annual dose of 385μSv/y. However the gamma outdoor dose rate varies from 307μSv/y to 366μSv/y with an average annual dose 385μSv/y. The annual outdoor gamma radiation dose is about %16 lower than the outdoor dose in Homs City. These measurements have indicated that environmental gamma doses in Homs City are relatively low. This is because that most of the soils and rocks in the area are limestone. (author)

  3. Estimation of effective doses to cavers based on radon measurements carried out in seven caves of the Bakony Mountains in Hungary

    International Nuclear Information System (INIS)

    Kavasi, Norbert; Somlai, Janos; Szeiler, Gabor; Szabo, Balazs; Schafer, Istvan; Kovacs, Tibor

    2010-01-01

    Nowadays, as the practice of extreme sports is spreading, potholing is becoming more and more popular. As a result, both the number of cavers and the time spent in the caves have been on the rise. There are some cavers known to have spent some 5000 h in caves over a span of 10 years. In poorly ventilated caves, radon exhalated from cave rocks and deposits may accumulate and cause significant doses to cavers. In this study, the radon concentration in seven caves in the Bakony Mountains, Hungary, was measured by continuous and integrated measurement devices. Measured values for the different caves were rather different, and varied between 50 and 24,000 Bq m -3 . The average radon concentration over the measurement period was approximately 10,000 Bq m -3 in five of the seven caves inspected. By assuming an average of 470 h year -1 spent in caves, effective doses to cavers were estimated. The expected annual effective dose, in case of an equilibrium factor of 0.6, was 19.7 mSv.

  4. TH-CD-206-08: An Anthropopathic Deformable Phantom for Geometric and Dose Accumulation Accuracy Validation of Deformable Image Registration

    Energy Technology Data Exchange (ETDEWEB)

    Liao, Y; Chen, H; Chen, J; Zhen, X; Zhou, L [Southern Medical University, Guangzhou, Guangdong (China); Gu, X [UT Southwestern Medical Center, Dallas, TX (United States)

    2016-06-15

    Purpose: To design and construct a three-dimensional (3D) anthropopathic abdominal phantom for evaluating deformable image registration (DIR) accuracy on images and dose deformation in adaptive radiation therapy (ART). Method: Organ moulds, including liver, kidney, spleen, stomach, vertebra and two metastasis tumors, are 3D printed using the contours from an ovarian cancer patient. The organ moulds are molded with deformable gels that made of different mixtures of polyvinyl chloride (PVC) and the softener dioctyl terephthalate. Gels with different densities are obtained by a polynomial fitting curve which describes the relation between the CT number and PVC-softener blending ratio. The rigid vertebras are constructed by moulding with white cement. The final abdominal phantom is assembled by arranging all the fabricated organs inside a hollow dummy according to their anatomies and sealed with deformable gel with averaged CT number of muscle and fat. Geometric and dosimetric landmarks are embedded inside the phantom for spatial accuracy and dose accumulation accuracy studies. Three DIR algorithms available in the open source DIR toolkit-DIRART, including the Demons, the Horn-Schunck and Lucas-Kanade method and the Level-Set Motion method, are tested using the constructed phantom. Results: Viscoelastic behavior is observed in the constructed deformable gel, which serves as an ideal material for the deformable phantom. The constructed abdominal phantom consists of highly realistic anatomy and the fabricated organs inside have close CT number to its reference patient. DIR accuracy studies conducted on the constructed phantom using three DIR approaches indicate that geometric accuracy of a DIR algorithm has achieved does not guarantee accuracy in dose accumulation. Conclusions: We have designed and constructed an anthropopathic abdominal deformable phantom with satisfactory elastic property, realistic organ density and anatomy. This physical phantom is recyclable and can

  5. Thermoluminescent dose measurements on board Salyut type orbital stations

    International Nuclear Information System (INIS)

    Akatov, Yu.A.; Arkhangelskij, V.V.; Aleksandrov, A.P.

    1984-06-01

    A small, vibration- and shock-resistant thermoluminescent dosemeter (TLD) system - named PILLE - was developed for orbital stations at the Central Research Institute for Physics, Hungary, to measure the cosmic radiation dose on-board. The first on-board measurements with this system were performed by B. Farkas, the Hungarian astronaut, on the Salyut-6 space station in 1980. The same instrument was used by other crews in the following years. Doses measured at different sites in Salyut-6 are presented. The dose rates varied from 0.7 to 0.11 mGy.day -1 . After the first cosmic measurements, the system was further developed. The minimum detectable dose of the new TLD system is 1 μGy, i.e. less by one order of magnitude than that of the former system. The self-irradiation dose rate of the TLD bulbs is also reduced by more than an order of magnitude to 10 nGy.h -1 , by use of potassium-free glass for the bulb envelope. This new type of PILLE TLD system is currently on-board Salyut-7. The dose rates (0.12-0.23 mGy.day -1 ) measured in 1983 are presented in detail. (author)

  6. Measurements of the personal dose equivalent

    International Nuclear Information System (INIS)

    Scarlat, F.; Scarisoreanu, A.; Badita, E.; Oane, M.; Mitru, E.

    2008-01-01

    Full text: The paper presents the results of measurements related to the personal dose equivalent in the rooms adjacent to NILPRP 7 MeV linear accelerator, by means of the secondary standard chamber T34035 Hp(10). The chamber was calibrated by PTB at S- 137 Cs (E av = 661.6 keV, T 1/2 11050 days) and has N H = 3.17x10 6 Sv/C calibration factor for the personal dose equivalent, Hp(10), at a depth of 10 mm in climatic reference conditions. The measurements were made for the two operation mode of the 7 MeV linac: electrons and bremsstrahlung

  7. Surface dose extrapolation measurements with radiographic film

    International Nuclear Information System (INIS)

    Butson, Martin J; Cheung Tsang; Yu, Peter K N; Currie, Michael

    2004-01-01

    Assessment of surface dose delivered from radiotherapy x-ray beams for optimal results should be performed both inside and outside the prescribed treatment fields. An extrapolation technique can be used with radiographic film to perform surface dose assessment for open field high energy x-ray beams. This can produce an accurate two-dimensional map of surface dose if required. Results have shown that the surface percentage dose can be estimated within ±3% of parallel plate ionization chamber results with radiographic film using a series of film layers to produce an extrapolated result. Extrapolated percentage dose assessment for 10 cm, 20 cm and 30 cm square fields was estimated to be 15% ± 2%, 29% ± 3% and 38% ± 3% at the central axis and relatively uniform across the treatment field. The corresponding parallel plate ionization chamber measurements are 16%, 27% and 37%, respectively. Surface doses are also measured outside the treatment field which are mainly due to scattered electron contamination. To achieve this result, film calibration curves must be irradiated to similar x-ray field sizes as the experimental film to minimize quantitative variations in film optical density caused by varying x-ray spectrum with field size. (note)

  8. Monitoring data related to the Chernobyl accident as measured in Israel during May-July 1986 and the assessment of the radiation doses to the population

    International Nuclear Information System (INIS)

    Schlesinger, T.; Biran, T.I.; Even, O.; Dukhan, R.; Shamai, Y.; Koch, J.; Tal, A.; Israeli, M.

    1987-07-01

    Environmental monitoring was undertaken on April 30 1986, to follow the effects of the Chernobyl accident on the quality of the environment in Israel. Measurements of air radioactive contamination were continuously taken to the end of July when air radioactive declined to values below 0.01 Bq/m 3 . Along air measurements, radioactive contamination of ground, rain and drinking water, grass, vegetation and food items such as vegetables, fruits, milk, meat etc. were taken as well. Assessment of the accumulated radiation doses due to the Chernobyl accident was conducted. The effective dose equivalent is estimated to be 46 μSv (4.6 mrem)

  9. Measuring radiation dose to patients undergoing fluoroscopically-guided interventions

    International Nuclear Information System (INIS)

    Lubis, L E; Badawy, M K

    2016-01-01

    The increasing prevalence and complexity of fluoroscopically guided interventions (FGI) raises concern regarding radiation dose to patients subjected to the procedure. Despite current evidence showing the risk to patients from the deterministic effects of radiation (e.g. skin burns), radiation induced injuries remain commonplace. This review aims to increase the awareness surrounding radiation dose measurement for patients undergoing FGI. A review of the literature was conducted alongside previous researches from the authors’ department. Studies pertaining to patient dose measurement, its formalism along with current advances and present challenges were reviewed. Current patient monitoring techniques (using available radiation dosimeters), as well as the inadequacy of accepting displayed dose as patient radiation dose is discussed. Furthermore, advances in real-time patient radiation dose estimation during FGI are considered. Patient dosimetry in FGI, particularly in real time, remains an ongoing challenge. The increasing occurrence and sophistication of these procedures calls for further advances in the field of patient radiation dose monitoring. Improved measuring techniques will aid clinicians in better predicting and managing radiation induced injury following FGI, thus improving patient care. (paper)

  10. The minimum measurable dose of the sensitive Harshaw TLDs

    International Nuclear Information System (INIS)

    Ben-Shachar, B.; German, U.; Naim, E.

    1991-01-01

    The TL-dose response was measured for the sensitive Harshaw manufactured phosphors (CaF 2 :Dy and CaF 2 :Tm), taking chips from the same batch and from different batches. The relative standard deviations were fitted to a semiempirical expression, from which the minimum measurable doses were derived and compared to the minimum measurable dose calculated by taking 3 times the standard deviation of unirradiated chips. The contribution of the individual calibration of each TLD chip was checked, as well

  11. Long-term accumulation and microdistribution of uranium in the bone and marrow of beagle dog.

    Science.gov (United States)

    Arruda-Neto, J D T; Manso Guevara, M V; Nogueira, G P; Taricano, I D; Saiki, M; Zamboni, C B; Bonamin, L V; Camargo, S P; Cestari, A C; Deppman, A; Garcia, F; Gouveia, A N; Guzman, F; Helene, O A M; Jorge, S A C; Likhachev, V P; Martins, M N; Mesa, J; Rodriguez, O; Vanin, V R

    2004-08-01

    The accumulation and microdistribution of uranium in the bone and marrow of Beagle dogs were determined by both neutron activation and neutron-fission analysis. The experiment started immediately after the weaning period, lasting till maturity. Two animal groups were fed daily with uranyl nitrate at concentrations of 20 and 100 microg g(-1) food. Of the two measuring techniques, uranium accumulated along the marrow as much as in the bone, contrary to the results obtained with single, acute doses. The role played by this finding for the evaluation of radiobiological long-term risks is discussed. It was demonstrated, by means of a biokinetical approach, that the long-term accumulation of uranium in bone and marrow could be described by a piling up of single dose daily incorporation.

  12. Field measurement and interpretation of beta doses and dose rates

    International Nuclear Information System (INIS)

    Selby, J.M.; Swinth, K.L.; Hooker, C.D.; Kenoyer, J.L.

    1983-01-01

    A wide variety of portable survey instruments employing GM, ionization chamber and scintillation detectors exist for the measurement of gamma exposure rates. Often these same survey instruments are used for monitoring beta fields. This is done by making measurements with and without a removable shield which is intended to shield out the non-penetrating component (beta) of the radiation field. The difference does not correspond to an absorbed dose rate for the beta field due to a variety of factors. Among these factors are the dependence on beta energy, source-detector geometries, mixed fields and variable ambient conditions. Attempting to use such measurements directly can lead to errors as high as a factor of 100. In many instances correction factors have been derived, that if properly applied, can reduce these errors substantially. However, this requires some knowledge of the beta spectra, calibration techniques and source geometry. This paper discusses some aspects of the proper use of instruments for beta measurements including the application of appropriate correction factors. Ionization type instruments are commonly used to measure beta dose rates. Through design and calibration these instruments will give an accurate reading only for uniform irradiation of the detection volume. Often in the field it is not feasible to meet these conditions. Large area uniform distributions of activity are not generally encountered and it is not possible to use large source-to-detector distances due to beta particle absorption in air. An example of correction factors required for various point sources is presented when a cutie pie ionization chamber is employed. The instrument reading is multiplied by the appropriate correction factor to obtain the dose rate at the window. When a different detector is used or for other geometries, a different set of correction factors must be used

  13. Student's music exposure: Full-day personal dose measurements.

    Science.gov (United States)

    Washnik, Nilesh Jeevandas; Phillips, Susan L; Teglas, Sandra

    2016-01-01

    Previous studies have shown that collegiate level music students are exposed to potentially hazardous sound levels. Compared to professional musicians, collegiate level music students typically do not perform as frequently, but they are exposed to intense sounds during practice and rehearsal sessions. The purpose of the study was to determine the full-day exposure dose including individual practice and ensemble rehearsals for collegiate student musicians. Sixty-seven college students of classical music were recruited representing 17 primary instruments. Of these students, 57 completed 2 days of noise dose measurements using Cirrus doseBadge programed according to the National Institute for Occupational Safety and Health criterion. Sound exposure was measured for 2 days from morning to evening, ranging from 7 to 9 h. Twenty-eight out of 57 (49%) student musicians exceeded a 100% daily noise dose on at least 1 day of the two measurement days. Eleven student musicians (19%) exceeded 100% daily noise dose on both days. Fourteen students exceeded 100% dose during large ensemble rehearsals and eight students exceeded 100% dose during individual practice sessions. Approximately, half of the student musicians exceeded 100% noise dose on a typical college schedule. This finding indicates that a large proportion of collegiate student musicians are at risk of developing noise-induced hearing loss due to hazardous sound levels. Considering the current finding, there is a need to conduct hearing conservation programs in all music schools, and to educate student musicians about the use and importance of hearing protection devices for their hearing.

  14. Radiochromic film calibration for low-energy seed brachytherapy dose measurement

    Energy Technology Data Exchange (ETDEWEB)

    Morrison, Hali, E-mail: hamorris@ualberta.ca; Menon, Geetha; Sloboda, Ron S. [Department of Medical Physics, Cross Cancer Institute, Edmonton, Alberta T6G 1Z2, Canada and Department of Oncology, University of Alberta, Edmonton, Alberta T6G 2R3 (Canada)

    2014-07-15

    Purpose: Radiochromic film dosimetry is typically performed for high energy photons and moderate doses characterizing external beam radiotherapy (XRT). The purpose of this study was to investigate the accuracy of previously established film calibration procedures used in XRT when applied to low-energy, seed-based brachytherapy at higher doses, and to determine necessary modifications to achieve similar accuracy in absolute dose measurements. Methods: Gafchromic EBT3 film was used to measure radiation doses upwards of 35 Gy from 75 kVp, 200 kVp, 6 MV, and (∼28 keV) I-125 photon sources. For the latter irradiations a custom phantom was built to hold a single I-125 seed. Film pieces were scanned with an Epson 10000XL flatbed scanner and the resulting 48-bit RGB TIFF images were analyzed using both FilmQA Pro software andMATLAB. Calibration curves relating dose and optical density via a rational functional form for all three color channels at each irradiation energy were determined with and without the inclusion of uncertainties in the measured optical densities and dose values. The accuracy of calibration curve variations obtained using piecewise fitting, a reduced film measurement area for I-125 irradiation, and a reduced number of dose levels was also investigated. The energy dependence of the film lot used was also analyzed by calculating normalized optical density values. Results: Slight differences were found in the resulting calibration curves for the various fitting methods used. The accuracy of the calibration curves was found to improve at low doses and worsen at high doses when including uncertainties in optical densities and doses, which may better represent the variability that could be seen in film optical density measurements. When exposing the films to doses > 8 Gy, two-segment piecewise fitting was found to be necessary to achieve similar accuracies in absolute dose measurements as when using smaller dose ranges. When reducing the film measurement

  15. Dose-rate and temperature dependent statistical damage accumulation model for ion implantation into silicon

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez-Mangas, J.M. [Dpto. de Electricidad y Electronica, Universidad de Valladolid, ETSI Telecomunicaciones, Campus Miguel Delibes, Valladolid E-47011 (Spain)]. E-mail: jesus.hernandez.mangas@tel.uva.es; Arias, J. [Dpto. de Electricidad y Electronica, Universidad de Valladolid, ETSI Telecomunicaciones, Campus Miguel Delibes, Valladolid E-47011 (Spain); Marques, L.A. [Dpto. de Electricidad y Electronica, Universidad de Valladolid, ETSI Telecomunicaciones, Campus Miguel Delibes, Valladolid E-47011 (Spain); Ruiz-Bueno, A. [Dpto. de Electricidad y Electronica, Universidad de Valladolid, ETSI Telecomunicaciones, Campus Miguel Delibes, Valladolid E-47011 (Spain); Bailon, L. [Dpto. de Electricidad y Electronica, Universidad de Valladolid, ETSI Telecomunicaciones, Campus Miguel Delibes, Valladolid E-47011 (Spain)

    2005-01-01

    Currently there are extensive atomistic studies that model some characteristics of the damage buildup due to ion irradiation (e.g. L. Pelaz et al., Appl. Phys. Lett. 82 (2003) 2038-2040). Our interest is to develop a novel statistical damage buildup model for our BCA ion implant simulator (IIS) code in order to extend its ranges of applicability. The model takes into account the abrupt regime of the crystal-amorphous transition. It works with different temperatures and dose-rates and also models the transition temperature. We have tested it with some projectiles (Ge, P) implanted into silicon. In this work we describe the new statistical damage accumulation model based on the modified Kinchin-Pease model. The results obtained have been compared with existing experimental results.

  16. Dose-rate and temperature dependent statistical damage accumulation model for ion implantation into silicon

    International Nuclear Information System (INIS)

    Hernandez-Mangas, J.M.; Arias, J.; Marques, L.A.; Ruiz-Bueno, A.; Bailon, L.

    2005-01-01

    Currently there are extensive atomistic studies that model some characteristics of the damage buildup due to ion irradiation (e.g. L. Pelaz et al., Appl. Phys. Lett. 82 (2003) 2038-2040). Our interest is to develop a novel statistical damage buildup model for our BCA ion implant simulator (IIS) code in order to extend its ranges of applicability. The model takes into account the abrupt regime of the crystal-amorphous transition. It works with different temperatures and dose-rates and also models the transition temperature. We have tested it with some projectiles (Ge, P) implanted into silicon. In this work we describe the new statistical damage accumulation model based on the modified Kinchin-Pease model. The results obtained have been compared with existing experimental results

  17. A naturally ventilated accumulator for integrating measurements of radon flux from soil

    International Nuclear Information System (INIS)

    Zhuo Weihai; Furukawa, Masahide; Tokonami, Shinji

    2007-01-01

    For long-term and large-scale measurements of the averaged 222 Rn fluxes from soils in the general environmental conditions, a simple measuring method was developed. 222 Rn exhaling from soils is accumulated by a naturally ventilated accumulator (NVA) and its concentration is measured with passive 222 Rn monitors set inside the NVA. The ventilation rate of the NVA is about 0.26 h -1 and it is hardly affected by the changes of meteorological conditions during field measurements. The air and soil conditions inside and outside of the NVA are nearly the same throughout the measurements. It indicates that the natural conditions of soils will not be significantly disturbed by the NVA. Field measurements confirmed that soil 222 Rn fluxes measured by the new method were in general agreement with the results measured by another commonly used method and theoretical estimations. As no electric power is needed as well as the operation and maintenance are easy, the low-cost system offers a promise as an improved technique for long-term measurements of soil 222 Rn fluxes in the general environmental conditions. (author)

  18. The measurement of patient doses from diagnostic x-rays

    International Nuclear Information System (INIS)

    Morris, N.D.; Solomon, S.B.

    1980-06-01

    As part of the National Health and Medical Research Council survey to determine the genetic and mean bone-marrow doses to the Australian population from the medical, dental and chiropractic uses of radiation sources, doses to patients undergoing X-ray diagnostic procedures were evaluated. The doses were measured using capsules of LiF or CaF 2 :Dy thermoluminescent dosemeters (TLD). The evaluation of the TLD measurements is described and the mean values of the skin doses for patients undergoing various radiographic examinations in Australia in 1970 are presented

  19. Online radiation dose measurement system for ATLAS experiment

    International Nuclear Information System (INIS)

    Mandic, I.; Cindro, V.; Dolenc, I.; Gorisek, A.; Kramberger, G.; Mikuz, M.; Bronner, J.; Hartet, J.; Franz, S.

    2009-01-01

    In experiments at Large Hadron Collider, detectors and electronics will be exposed to high fluxes of photons, charged particles and neutrons. Damage caused by the radiation will influence performance of detectors. It will therefore be important to continuously monitor the radiation dose in order to follow the level of degradation of detectors and electronics and to correctly predict future radiation damage. A system for online radiation monitoring using semiconductor radiation sensors at large number of locations has been installed in the ATLAS experiment. Ionizing dose in SiO 2 will be measured with RadFETs, displacement damage in silicon in units of 1-MeV(Si) equivalent neutron fluence with p-i-n diodes. At 14 monitoring locations where highest radiation levels are expected the fluence of thermal neutrons will be measured from current gain degradation in dedicated bipolar transistors. The design of the system and tests of its performance in mixed radiation field is described in this paper. First results from this test campaign confirm that doses can be measured with sufficient sensitivity (mGy for total ionizing dose measurements, 10 9 n/cm 2 for NIEL (non-ionizing energy loss) measurements, 10 12 n/cm 2 for thermal neutrons) and accuracy (about 20%) for usage in the ATLAS detector

  20. A novel dose uncertainty model and its application for dose verification

    International Nuclear Information System (INIS)

    Jin Hosang; Chung Heetaek; Liu Chihray; Palta, Jatinder; Suh, Tae-Suk; Kim, Siyong

    2005-01-01

    Based on statistical approach, a novel dose uncertainty model was introduced considering both nonspatial and spatial dose deviations. Non-space-oriented uncertainty is mainly caused by dosimetric uncertainties, and space-oriented dose uncertainty is the uncertainty caused by all spatial displacements. Assuming these two parts are independent, dose difference between measurement and calculation is a linear combination of nonspatial and spatial dose uncertainties. Two assumptions were made: (1) the relative standard deviation of nonspatial dose uncertainty is inversely proportional to the dose standard deviation σ, and (2) the spatial dose uncertainty is proportional to the gradient of dose. The total dose uncertainty is a quadratic sum of the nonspatial and spatial uncertainties. The uncertainty model provides the tolerance dose bound for comparison between calculation and measurement. In the statistical uncertainty model based on a Gaussian distribution, a confidence level of 3σ theoretically confines 99.74% of measurements within the bound. By setting the confidence limit, the tolerance bound for dose comparison can be made analogous to that of existing dose comparison methods (e.g., a composite distribution analysis, a γ test, a χ evaluation, and a normalized agreement test method). However, the model considers the inherent dose uncertainty characteristics of the test points by taking into account the space-specific history of dose accumulation, while the previous methods apply a single tolerance criterion to the points, although dose uncertainty at each point is significantly different from others. Three types of one-dimensional test dose distributions (a single large field, a composite flat field made by two identical beams, and three-beam intensity-modulated fields) were made to verify the robustness of the model. For each test distribution, the dose bound predicted by the uncertainty model was compared with simulated measurements. The simulated

  1. Simulation-based computation of dose to humans in radiological environments

    International Nuclear Information System (INIS)

    Breazeal, N.L.; Davis, K.R.; Watson, R.A.; Vickers, D.S.; Ford, M.S.

    1996-03-01

    The Radiological Environment Modeling System (REMS) quantifies dose to humans working in radiological environments using the IGRIP (Interactive Graphical Robot Instruction Program) and Deneb/ERGO simulation software. These commercially available products are augmented with custom C code to provide radiation exposure information to, and collect radiation dose information from, workcell simulations. Through the use of any radiation transport code or measured data, a radiation exposure input database may be formulated. User-specified IGRIP simulations utilize these databases to compute and accumulate dose to programmable human models operating around radiation sources. Timing, distances, shielding, and human activity may be modeled accurately in the simulations. The accumulated dose is recorded in output files, and the user is able to process and view this output. The entire REMS capability can be operated from a single graphical user interface

  2. Simulation-based computation of dose to humans in radiological environments

    Energy Technology Data Exchange (ETDEWEB)

    Breazeal, N.L. [Sandia National Labs., Livermore, CA (United States); Davis, K.R.; Watson, R.A. [Sandia National Labs., Albuquerque, NM (United States); Vickers, D.S. [Brigham Young Univ., Provo, UT (United States). Dept. of Electrical and Computer Engineering; Ford, M.S. [Battelle Pantex, Amarillo, TX (United States). Dept. of Radiation Safety

    1996-03-01

    The Radiological Environment Modeling System (REMS) quantifies dose to humans working in radiological environments using the IGRIP (Interactive Graphical Robot Instruction Program) and Deneb/ERGO simulation software. These commercially available products are augmented with custom C code to provide radiation exposure information to, and collect radiation dose information from, workcell simulations. Through the use of any radiation transport code or measured data, a radiation exposure input database may be formulated. User-specified IGRIP simulations utilize these databases to compute and accumulate dose to programmable human models operating around radiation sources. Timing, distances, shielding, and human activity may be modeled accurately in the simulations. The accumulated dose is recorded in output files, and the user is able to process and view this output. The entire REMS capability can be operated from a single graphical user interface.

  3. Measurement of dosimetric parameters and dose verification in stereotactic radiosurgery (SRS)

    International Nuclear Information System (INIS)

    Reduan Abdullah; Nik Ruzman Nik Idris; Ahmad Lutfi Yusof; Mazurawati Mohamed

    2013-01-01

    Full-text: The purpose of this study was to measure the dosimetric parameters for small photon beams to be used as input data treatment planning computer system (TPS) and to verify dose calculated by TPS in Stereotactic Radiosurgery (SRS) procedure. The beam data required were Percentage Depth Dose (PDD), Off-axis Ratio (OAR), and Scatter Factor of Relative Output Factor. Small beams of 5 mm to 45 mm diameter circular cone collimators used in SRS were utilized for beam data measurements measured using pinpoint 3D ionization chamber (0.016 cc). For second part of this study, we reported the important quality assurance (QA) procedures before SRS treatment that influenced the dose delivery. These QA procedures consist of measurements on the accuracy in target localization and room laser alignment. The dose calculated to be delivered for treatment was verified using pinpoint 3D ionization chamber and TLD 100H. The mean deviation of measured dose using TLD 100H compared to calculated dose was 3.37 %. Beside that, pinpoint ionization 3D chamber give more accurate results of dose compared to TLD 100H. The measured dose using pinpoint 3D ionization chamber are good agreement with calculated dose by TPS with deviation of 2.17 %. The results are acceptable such as recommended by International Commission on Radiation Units and Measurements (ICRU) Report No. 50 (1993) that dose delivered to the target volume must be within ±5 % error. (author)

  4. Measurement of the reduction of terrestrial gamma-ray dose rates by the snow cover using TL-dosimeters

    International Nuclear Information System (INIS)

    Sakamoto, Ryuichi; Saito, Kimiaki; Nagaoka, Toshi; Tsutsumi, Masahiro; Moriuchi, Shigeru

    1990-12-01

    The objective of the investigation is to make clear the effect of the snow cover on environmental gamma-ray field. The reduction in the natural terrestrial gamma-ray dose rate due to snow cover was measured by TL-dosimeters. The measurements were performed in autumn before snowfall and in winter from September 1987 through March 1988 in Nagaoka city, Niigata prefecture. The dosimeters were set at four points, both outside and inside of the houses, for three months. The penetration factors (ratios of terrestrial gamma-ray dose accumulated during snow covered period to those during snow free period) were 0.54-0.67 in the open field, and 0.73-0.95 in the houses. According to theoretical calculation by the Monte Carlo method and the published snowfall data, the corresponding penetration factor was estimated at 0.54 in an ideal open field. As a result, the measured penetration factors were larger than calculated one by 24 % at maximum. The variation of dose rate inside houses by the difference of the amount of snow fall has been investigated. In general, though the amount of snow fall changes every year, dose rates inside the house were proved to be affected little by them. And, the optimum value of snow density which adapted for inference of penetration factor was found to be 0.3 g/cm 3 . The penetration factors inferred from snowdepth data for the year distributed between 0.6 and 1.0 in winter from November 1985 through April 1986 in Niigata prefecture. (author)

  5. Experimental measurements of spatial dose distributions in radiosurgery treatments

    International Nuclear Information System (INIS)

    Avila-Rodriguez, M. A.; Rodriguez-Villafuerte, M.; Diaz-Perches, R.; Perez-Pastenes, M. A.

    2001-01-01

    The measurement of stereotactic radiosurgery dose distributions requires an integrating, high-resolution dosimeter capable of providing a spatial map of absorbed dose. This paper describes the use of a commercial radiochromic dye film (GafChromic MD-55-2) to measure radiosurgery dose distributions with 6 MV X-rays in a head phantom. The response of the MD-55-2 was evaluated by digitizing and analyzing the films with conventional computer systems. Radiosurgery dose distributions were measured using the radiochromic film in a spherical acrylic phantom of 16 cm diameter undergoing a typical SRS treatment as a patient, and were compared with dose distributions provided by the treatment planning system. The comparison lead to mean radial differences of ±0.6 mm, ±0.9 mm, ±1.3 mm, ±1.9 mm, and ±2.8 mm, for the 80, 60, 50, 40, and 30% isodose curves, respectively. It is concluded that the radiochromic film is a convenient and useful tool for radiosurgery treatment planning validation

  6. Motion as a perturbation: Measurement-guided dose estimates to moving patient voxels during modulated arc deliveries

    Energy Technology Data Exchange (ETDEWEB)

    Feygelman, Vladimir; Zhang, Geoffrey; Hunt, Dylan; Opp, Daniel [Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida 33612 (United States); Stambaugh, Cassandra [Department of Physics, University of South Florida, Tampa, Florida 33612 (United States); Wolf, Theresa K. [Live Oak Technologies LLC, Kirkwood, Missouri 63122 (United States); Nelms, Benjamin E. [Canis Lupus LLC, Merrimac, Wisconsin 53561 (United States)

    2013-02-15

    Purpose: To present a framework for measurement-guided VMAT dose reconstruction to moving patient voxels from a known motion kernel and the static phantom data, and to validate this perturbation-based approach with the proof-of-principle experiments. Methods: As described previously, the VMAT 3D dose to a static patient can be estimated by applying a phantom measurement-guided perturbation to the treatment planning system (TPS)-calculated dose grid. The fraction dose to any voxel in the presence of motion, assuming the motion kernel is known, can be derived in a similar fashion by applying a measurement-guided motion perturbation. The dose to the diodes in a helical phantom is recorded at 50 ms intervals and is transformed into a series of time-resolved high-density volumetric dose grids. A moving voxel is propagated through this 4D dose space and the fraction dose to that voxel in the phantom is accumulated. The ratio of this motion-perturbed, reconstructed dose to the TPS dose in the phantom serves as a perturbation factor, applied to the TPS fraction dose to the similarly situated voxel in the patient. This approach was validated by the ion chamber and film measurements on four phantoms of different shape and structure: homogeneous and inhomogeneous cylinders, a homogeneous cube, and an anthropomorphic thoracic phantom. A 2D motion stage was used to simulate the motion. The stage position was synchronized with the beam start time with the respiratory gating simulator. The motion patterns were designed such that the motion speed was in the upper range of the expected tumor motion (1-1.4 cm/s) and the range exceeded the normally observed limits (up to 5.7 cm). The conformal arc plans for X or Y motion (in the IEC 61217 coordinate system) consisted of manually created narrow (3 cm) rectangular strips moving in-phase (tracking) or phase-shifted by 90 Degree-Sign (crossing) with respect to the phantom motion. The XY motion was tested with the computer-derived VMAT

  7. Motion as a perturbation: Measurement-guided dose estimates to moving patient voxels during modulated arc deliveries

    International Nuclear Information System (INIS)

    Feygelman, Vladimir; Zhang, Geoffrey; Hunt, Dylan; Opp, Daniel; Stambaugh, Cassandra; Wolf, Theresa K.; Nelms, Benjamin E.

    2013-01-01

    Purpose: To present a framework for measurement-guided VMAT dose reconstruction to moving patient voxels from a known motion kernel and the static phantom data, and to validate this perturbation-based approach with the proof-of-principle experiments. Methods: As described previously, the VMAT 3D dose to a static patient can be estimated by applying a phantom measurement-guided perturbation to the treatment planning system (TPS)-calculated dose grid. The fraction dose to any voxel in the presence of motion, assuming the motion kernel is known, can be derived in a similar fashion by applying a measurement-guided motion perturbation. The dose to the diodes in a helical phantom is recorded at 50 ms intervals and is transformed into a series of time-resolved high-density volumetric dose grids. A moving voxel is propagated through this 4D dose space and the fraction dose to that voxel in the phantom is accumulated. The ratio of this motion-perturbed, reconstructed dose to the TPS dose in the phantom serves as a perturbation factor, applied to the TPS fraction dose to the similarly situated voxel in the patient. This approach was validated by the ion chamber and film measurements on four phantoms of different shape and structure: homogeneous and inhomogeneous cylinders, a homogeneous cube, and an anthropomorphic thoracic phantom. A 2D motion stage was used to simulate the motion. The stage position was synchronized with the beam start time with the respiratory gating simulator. The motion patterns were designed such that the motion speed was in the upper range of the expected tumor motion (1–1.4 cm/s) and the range exceeded the normally observed limits (up to 5.7 cm). The conformal arc plans for X or Y motion (in the IEC 61217 coordinate system) consisted of manually created narrow (3 cm) rectangular strips moving in-phase (tracking) or phase-shifted by 90° (crossing) with respect to the phantom motion. The XY motion was tested with the computer-derived VMAT MLC

  8. First Results from the Online Radiation Dose Monitoring System in ATLAS experiment

    CERN Document Server

    Mandić, I; The ATLAS collaboration; Deliyergiyev, M; Gorišek, A; Kramberger, G; Mikuž, M; Franz, S; Hartert, J; Dawson, I; Miyagawa, P; Nicolas, L

    2011-01-01

    High radiation doses which will accumulate in components of ATLAS experiment during data taking will causes damage to detectors and readout electronics. It is therefore important to continuously monitor the doses to estimate the level of degradation caused by radiation. Online radiation monitoring system measures ionizing dose in SiO2 , displacement damage in silicon in terms of 1-MeV(Si) equivalent neutron fluence and fluence of thermal neutrons at several locations in ATLAS detector. In this paper design of the system, results of measurements and comparison of measured integrated doses and fluences with predictions from FLUKA simulation will be shown.

  9. Standardization of high-dose measurement of electron and gamma ray absorbed doses and dose rates

    International Nuclear Information System (INIS)

    McLaughlin, W.L.

    1985-01-01

    Intense electron beams and gamma radiation fields are used for sterilizing medical devices, treating municipal wastes, processing industrial goods, controlling parasites and pathogens, and extending the shelf-life of foods. Quality control of such radiation processes depends largely on maintaining measurement quality assurance through sound dosimetry procedures in the research leading to each process, in the commissioning of that process, and in the routine dose monitoring practices. This affords documentation as to whether satisfactory dose uniformity is maintained throughout the product and throughout the process. Therefore, dosimetry at high doses and dose rates must in many radiation processes be standardized carefully, so that 'dosimetry release' of a product is verified. This standardization is initiated through preliminary dosimetry intercomparison studies such as those sponsored recently by the IAEA. This is followed by establishing periodic exercises in traceability to national or international standards of absorbed dose and dose rate. Traceability is achieved by careful selection of dosimetry methods and proven reference dosimeters capable of giving sufficiently accurate and precise 'transfer' dose assessments: (1) they must be calibrated or have well-established radiation-yield indices; (2) their radiation response characteristics must be reproducible and cover the dose range of interest; (3) they must withstand the rigours of back-and-forth mailing between a central standardizing laboratory and radiation processing facilities, without excessive errors arising due to instabilities, dosimeter batch non-uniformities, and environmental and handling stresses. (author)

  10. Remote control and data processing for measurement of radiation dose

    International Nuclear Information System (INIS)

    Zhou Yu; Luo Yisheng; Guo Yong; Ji Gang; Wang Xinggong; Zhang Hong; Zhang Wenzhong

    2004-01-01

    Objective: To protect the workers from the reactor radiation and to improve the accuracy and efficiency of neutron dose measurement. Methods: With the application of remote control technology, a remote control and automatic measurement system for radiation dose measurement(especially for neutron dose) was set up. A Model 6517A electrometer was operated all automatically over RS-232 serial interface using SCPI commands with a computer. Results: The workers could stay far from the reactor and be able to control the portable computer in site though internet or LAN and then to control the 6517A electrometer to implement the dose measurement. After the measurement, the data were transferred to the remote computer near the workers and shared by many experts at the first time through the net. Conclusion: This is the first time that the remote control technology is applied in radiation dose measurement, which has so far been considered can only be performed at a near place. This new system can meet the need of neutron radiobiology researches as well as of the safety and health of the workers. (author)

  11. Measurement and comparison of skin dose using OneDose MOSFET and Mobile MOSFET for patients with acute lymphoblastic leukemia.

    Science.gov (United States)

    Mattar, Essam H; Hammad, Lina F; Al-Mohammed, Huda I

    2011-07-01

    Total body irradiation is a protocol used to treat acute lymphoblastic leukemia in patients prior to bone marrow transplant. It is involved in the treatment of the whole body using a large radiation field with extended source-skin distance. Therefore measuring and monitoring the skin dose during the treatment is important. Two kinds of metal oxide semiconductor field effect transistor (OneDose MOSFET and mobile MOSEFT) dosimeter are used during the treatment delivery to measure the skin dose to specific points and compare it with the target prescribed dose. The objective of this study was to compare the variation of skin dose in patients with acute lymphatic leukemia (ALL) treated with total body irradiation (TBI) using OneDose MOSFET detectors and Mobile MOSFET, and then compare both results with the target prescribed dose. The measurements involved 32 patient's (16 males, 16 females), aged between 14-30 years, with an average age of 22.41 years. One-Dose MOSFET and Mobile MOSFET dosimetry were performed at 10 different anatomical sites on every patient. The results showed there was no variation between skin dose measured with OneDose MOSFET and Mobile MOSFET in all patients. Furthermore, the results showed for every anatomical site selected there was no significant difference in the dose delivered using either OneDose MOSFET detector or Mobile MOSFET as compared to the prescribed dose. The study concludes that One-Dose MOSFET detectors and Mobile MOSFET both give a direct read-out immediately after the treatment; therefore both detectors are suitable options when measuring skin dose for total body irradiation treatment.

  12. In situ measurements of dose rates from terrestrial gamma rays

    International Nuclear Information System (INIS)

    Horng, M.C.; Jiang, S.H.

    2002-01-01

    A portable, high purity germanium (HPGe) detector was employed for the performance of in situ measurements of radionuclide activity concentrations in the ground in Taiwan, at altitudes ranging from sea level to 3900 m. The absolute peak efficiency of the HPGe detector for a gamma-ray source uniformly distributed in the semi-infinite ground was determined using a semi-empirical method. The gamma-ray dose rates from terrestrial radionuclides were calculated from the measured activity levels using recently published dose rate conversion factors. The absorbed dose rate in air due to cosmic rays was derived by subtracting the terrestrial gamma-ray dose rate from the overall absorbed dose rate in air measured using a high-pressure ionization chamber. The cosmic-ray dose rate calculated as a function of altitude, was found to be in good agreement with the data reported by UNSCEAR. (orig.)

  13. BeO-OSL detectors for dose measurements in cell cultures

    International Nuclear Information System (INIS)

    Andreeff, M.; Freudenberg, R.; Kotzerke, J.; Sommer, D.; Reichelt, U.; Henniger, J.

    2009-01-01

    Aim: The absorbed dose is an important parameter in experiments involving irradiation of cells in vitro with unsealed radionuclides. Typically, this is estimated with a model calculation, although the results thus obtained cannot be verified. Generally used real-time measurement methods are not applicable in this setting. A new detector material with in vitro suitability is the subject of this work. Methods: Optically-stimulated luminescence (OSL) dosimeters based on beryllium oxide (BeO) were used for dose measurement in cell cultures exposed to unsealed radionuclides. Their qualitative properties (e. g. energy-dependent count rate sensitivity, fading, contamination by radioactive liquids) were determined and compared to the results of a Monte Carlo simulation (using AMOS software). OSL dosimeters were tested in common cell culture setups with a known geometry. Results: Dose reproducibility of the OSL dosimeters was ± 1.5%. Fading at room temperature was 0.07% per day. Dose loss (optically-stimulated deletion) under ambient lighting conditions was 0.5% per minute. The Monte Carlo simulation for the relative sensitivity at different beta energies provided corresponding results to those obtained with the OSL dosimeters. Dose profile measurements using a 6 well plate and 14 ml PP tube showed that the geometry of the cell culture vessel has a marked influence on dose distribution with 188 Re. Conclusion: A new dosimeter system was calibrated with β-emitters of different energy. It turned out as suitable for measuring dose in liquids. The dose profile measurements obtained are suitably precise to be used as a check against theoretical dose calculations. (orig.)

  14. The Australian Commonwealth standard of measurement for absorbed radiation dose

    International Nuclear Information System (INIS)

    Sherlock, S.L.

    1990-06-01

    This report documents the absorbed dose standard for photon beams in the range from 1 to 25 MeV. Measurements of absorbed dose in graphite irradiated by a beam of cobalt-60 gamma rays from an Atomic Energy of Canada Limited (AECL) E1 Dorado 6 teletherapy unit are reported. The measurements were performed using a graphite calorimeter, which is the primary standard for absorbed dose. The measurements are used to calibrate a working standard ion chamber in terms of absorbed dose in graphite. Details of the methods, results and correction factors applied are given in Appendices. 13 refs., 6 tabs., 6 figs

  15. Assessment of concomitant testicular dose with radiochromic film

    International Nuclear Information System (INIS)

    Fricker, Katherine; Thompson, Christine; Meyer, Juergen

    2013-01-01

    To assess the suitability of EBT2 and XRQA2 Gafchromic film for measuring low doses in the periphery of treatment fields, and to measure the accumulative concomitant dose to the contralateral testis resulting from CT imaging, pre-treatment imaging (CBCT) and seminoma radiotherapy with and without gonadal shielding. Superficial peripheral dose measurements made using EBT2 Gafchromic film on the surface of water equivalent material were compared to measurements made with an ionisation chamber in a water phantom to evaluate the suitability and accuracy of the film dosimeter for such measurements. Similarly, XRQA2 was used to measure surface doses within a kilovoltage beam and compared with ionisation chamber measurements. Gafchromic film was used to measure CT, CBCT and seminoma treatment related testicular doses on an anthropomorphic phantom. Doses were assessed for two clinical plans, both with and without gonadal shielding. Testicular doses resulting from the treatment of up to 0.83 ± 0.17 Gy were measured per treatment. Additional doses of up to 0.49 ± 0.01 and 2.35 ± 0.05 cGy were measured per CBCT and CT image, respectively. Reductions in the testicular dose in the order of 10, 36 and 78 % were observed when gonadal shielding was fitted for treatment, CT and CBCT imaging, respectively. Gafchromic film was found to be suitable for measuring dose in the periphery of treatment fields. The dose to the testis should be limited to minimise the risk of radiation related side effects. This can be achieved by using appropriate gonadal shielding, irrespective of the treatment fields employed.

  16. Computerized assessment of the measurement of individual doses

    International Nuclear Information System (INIS)

    Kiibus, A.

    1981-06-01

    The department for the measurements of individual doses makes regular dose controls by means of film badges for approximately 14000 individuals. The operation is facilitated by a Honeywell Bull Mini 6 Mod 43 computer. The computer language is COBOL applied to registering of in-data such as delivery of badges, film development, calibration, invoices, recording of individual doses and customers. The print-out consists of customers, badge codes, dosimeter lists, development specifications, dose statements, addresses, bills, dose statistics and the register of individuals. As a consequence of charges the activity is financially self-supporting. (G.B.)

  17. Measurements of the Chernobyl accident fallout in Israel and the assessment of the radiation doses to the population

    International Nuclear Information System (INIS)

    Stern, E.; Ilberg, D.; Brenner, S.

    1997-01-01

    Israel is located approximately 2000 km southeast of Chernobyl. The fallout from the accident in Chernobyl reactor no. 4 on April 26, 1986 arrived in Israel on the night of May 2nd. Following the accident, studies of the radiological effects were initiated by many countries some of them many thousands of kilometers away. These studies can be characterized by three periods: a) First months following the accident - Measurements were taken to assess the immediate impact and to propose countermeasures that would reduce doses incurred by the population. b) First years following the accidents - Measurements were taken to validate that radioecological effects are well below any regulatory limits, from both the fallout radioactivity in the country and import of food coming from other affected areas. c) The last years (e.g. 1990-1995) - Measurements were taken within the regular program of environmental radioactivity surveillance. In this paper we have compiled the results of the studies in Israel which have followed the three phases mentioned above. Assessment of the accumulated potential radiation doses to the population in Israel was made based on the results of those measurements covered in the three phases, considering the various possible pathways

  18. Analytical evaluation of dose measurement of critical accident at SILENE (Contract research)

    CERN Document Server

    Nakamura, T; Tonoike, K

    2003-01-01

    Institute for Radioprotection and Nuclear Safety (IRSN) and the OECD Nuclear Energy Agency (NEA) jointly organized SILENE Accident Dosimetry Intercomparison Exercise to intercompare the dose measurement systems of participating countries. Each participating country carried out dose measurements in the same irradiation field, and the measurement results were mutually compared. The participated in the exercise to measure the doses of gamma rays and neutron from SILENE by using thermoluminescence dosimeters (TLD's) and an alanine dosimeter. In this examination, the derived evaluation formulae for obtaining a tissue-absorbed dose from measured value (ambient dose equivalent) of TLD for neutron. We reported the tissue-absorbed dose computed using this evaluation formula to OECD/NEA. TLD's for neutron were irradiated in the TRACY facility to verify the evaluation formulae. The results of TLD's were compared with the calculations of MCNP and measurements with alanine dose meter. We found that the ratio of the dose b...

  19. Online radiation dose measurement system for ATLAS experiment

    Energy Technology Data Exchange (ETDEWEB)

    Mandic, I.; Cindro, V.; Dolenc, I.; Gorisek, A.; Kramberger, G. [Jozef Stefan Institute, Jamova 39, Ljubljana (Slovenia); Mikuz, M. [Jozef Stefan Institute, Jamova 39, Ljubljana (Slovenia); Faculty of Mathematics and Physics, University of Ljubljana (Slovenia); Bronner, J.; Hartet, J. [Physikalisches Institut, Universitat Freiburg, Hermann-Herder-Str. 3, Freiburg (Germany); Franz, S. [CERN, Geneva (Switzerland)

    2009-07-01

    In experiments at Large Hadron Collider, detectors and electronics will be exposed to high fluxes of photons, charged particles and neutrons. Damage caused by the radiation will influence performance of detectors. It will therefore be important to continuously monitor the radiation dose in order to follow the level of degradation of detectors and electronics and to correctly predict future radiation damage. A system for online radiation monitoring using semiconductor radiation sensors at large number of locations has been installed in the ATLAS experiment. Ionizing dose in SiO{sub 2} will be measured with RadFETs, displacement damage in silicon in units of 1-MeV(Si) equivalent neutron fluence with p-i-n diodes. At 14 monitoring locations where highest radiation levels are expected the fluence of thermal neutrons will be measured from current gain degradation in dedicated bipolar transistors. The design of the system and tests of its performance in mixed radiation field is described in this paper. First results from this test campaign confirm that doses can be measured with sufficient sensitivity (mGy for total ionizing dose measurements, 10{sup 9} n/cm{sup 2} for NIEL (non-ionizing energy loss) measurements, 10{sup 12} n/cm{sup 2} for thermal neutrons) and accuracy (about 20%) for usage in the ATLAS detector

  20. An international intercomparison of absorbed dose measurements for radiation therapy

    International Nuclear Information System (INIS)

    Taiman Kadni; Noriah Mod Ali

    2002-01-01

    Dose intercomparison on an international basis has become an important component of quality assurance measurement i.e. to check the performance of absorbed dose measurements in radiation therapy. The absorbed dose to water measurements for radiation therapy at the SSDL, MINT have been regularly compared through international intercomparison programmes organised by the IAEA Dosimetry Laboratory, Seibersdorf, Austria such as IAEA/WHO TLD postal dose quality audits and the Intercomparison of therapy level ionisation chamber calibration factors in terms of air kerma and absorbed dose to water calibration factors. The results of these intercomparison in terms of percentage deviations for Cobalt 60 gamma radiation and megavoltage x-ray from medical linear accelerators participated by the SSDL-MINT during the year 1985-2001 are within the acceptance limit. (Author)

  1. Dose-rate-dependent damage of cerium dioxide in the scanning transmission electron microscope.

    Science.gov (United States)

    Johnston-Peck, Aaron C; DuChene, Joseph S; Roberts, Alan D; Wei, Wei David; Herzing, Andrew A

    2016-11-01

    Beam damage caused by energetic electrons in the transmission electron microscope is a fundamental constraint limiting the collection of artifact-free information. Through understanding the influence of the electron beam, experimental routines may be adjusted to improve the data collection process. Investigations of CeO 2 indicate that there is not a critical dose required for the accumulation of electron beam damage. Instead, measurements using annular dark field scanning transmission electron microscopy and electron energy loss spectroscopy demonstrate that the onset of measurable damage occurs when a critical dose rate is exceeded. The mechanism behind this phenomenon is that oxygen vacancies created by exposure to a 300keV electron beam are actively annihilated as the sample re-oxidizes in the microscope environment. As a result, only when the rate of vacancy creation exceeds the recovery rate will beam damage begin to accumulate. This observation suggests that dose-intensive experiments can be accomplished without disrupting the native structure of the sample when executed using dose rates below the appropriate threshold. Furthermore, the presence of an encapsulating carbonaceous layer inhibits processes that cause beam damage, markedly increasing the dose rate threshold for the accumulation of damage. Published by Elsevier B.V.

  2. KERMA-based radiation dose management system for real-time patient dose measurement

    Science.gov (United States)

    Kim, Kyo-Tae; Heo, Ye-Ji; Oh, Kyung-Min; Nam, Sang-Hee; Kang, Sang-Sik; Park, Ji-Koon; Song, Yong-Keun; Park, Sung-Kwang

    2016-07-01

    Because systems that reduce radiation exposure during diagnostic procedures must be developed, significant time and financial resources have been invested in constructing radiation dose management systems. In the present study, the characteristics of an existing ionization-based system were compared to those of a system based on the kinetic energy released per unit mass (KERMA). Furthermore, the feasibility of using the KERMA-based system for patient radiation dose management was verified. The ionization-based system corrected the effects resulting from radiation parameter perturbations in general radiography whereas the KERMA-based system did not. Because of this difference, the KERMA-based radiation dose management system might overestimate the patient's radiation dose due to changes in the radiation conditions. Therefore, if a correction factor describing the correlation between the systems is applied to resolve this issue, then a radiation dose management system can be developed that will enable real-time measurement of the patient's radiation exposure and acquisition of diagnostic images.

  3. Dose measurements in controlled area and laboratory of TRIGA IPR-R1 reactor

    International Nuclear Information System (INIS)

    Maretti Junior, Fausto; Alvarenga, Frederico Ladeia

    2005-01-01

    The workers doses in exposure areas to the radiation are so important for a Radioprotection Quality Program, as well as to guarantee the workers safety. For that it is necessary to raise the doses in the radiation areas, to obtain the accumulated dose in certain procedures for detailed studies. Several risings were accomplished to obtain the radiation levels in the areas where the workers are exposed due the operation of a research nuclear reactor and in the radioisotopes manipulation laboratories of a nuclear institute. The radiation levels and doses can be observed through graphs in the dependences of the Controlled Area 1 (AC-1) and the Reactor Laboratory. Those limits are in according of the CNEN-NE-3.01 work limits rules. The conclusion of the work allowed to demonstrate that the Laboratory of the Reactor and AC-1, have booth an effective radiological program with efficient operational practices that contributes with low doses to the workers. (author)

  4. Measurements and applications of dose indices in radiography

    International Nuclear Information System (INIS)

    Chen, T.R.; Tyan, Y.S.; Yang, J.J.; Shao, C.H.; Lin, J.Y.; Tung, C.J.

    2011-01-01

    Assessments of radiation dose and image quality are required in diagnostic radiography for quality assurance and optimization studies. In work currently being undertaken, dose indices were measured and image quality evaluated for a chest PA procedure. Thermoluminescent dosimeters of the GR-200 type were attached to the entrance and exit surfaces and placed at various depths of the PMMA phantom to measure the entrance surface dose, the exit surface dose, and the organ dose index. The effective dose was estimated from the entrance surface dose using PCXMC software. Two contrast-detail image plates, one with air holes for the low contrast objects and the other with gypsum holes for the high contrast objects, were used to obtain radiographic images. This image plate was placed at different depths from the entrance surface of the phantom to simulate objects at different positions in the body. Each image was evaluated by three independent radiologists to determine image quality. Analyses of radiation dose versus image quality were performed to determine the optimal technical factors such as, filtration and tube potential. It was found that an 11-cm thick PMMA phantom best simulated the patients. The fractional dose backscattered from this phantom was between 22% and 27% for kVp’s between 66 and 133. Optimization analyses showed that no extra filter was required. For low contrast objects, an optimal choice of tube potential was 120 kVp. For high contrast objects, a kVp as low as 77 kVp could be used, depending on the image quality requirement.

  5. Some cosmic radiation dose measurements aboard flights connecting Zagreb Airport

    International Nuclear Information System (INIS)

    Vukovic, B.; Radolic, V.; Lisjak, I.; Vekic, B.; Poje, M.; Planinic, J.

    2008-01-01

    When primary particles from space, mainly protons, enter the atmosphere, they produce interactions with air nuclei, and cosmic-ray showers are induced. The radiation field at aircraft altitude is complex, with different types of particles, mainly photons, electrons, positrons and neutrons, with a large energy range. The non-neutron component of cosmic radiation dose aboard A320 and ATR40 aircraft was measured with TLD-100 (LiF:Mg,Ti) detectors and the Mini 6100 semiconductor dosimeter; the neutron dose was measured with the neutron dosimeter consisted of LR-115 track detector and boron foil BN-1 or 10 B converter. The estimated occupational effective dose for the aircraft crew (A320) working 500 h per year was 1.64 mSv. Another experiment was performed at the flights Zagreb-Paris-Buenos Aires and reversely, when one measured non-neutron cosmic radiation dose; for 26.7 h of flight, the MINI 6100 dosimeter gave an average dose rate of 2.3 μSv/h and the TLD dosimeter registered the dose equivalent of 75 μSv or the average dose rate of 2.7 μSv/h; the neutron dosimeter gave the dose rate of 2.4 μSv/h. In the same month, February 2005, a traveling to Japan (24-h-flight: Zagreb-Frankfurt-Tokyo and reversely) and the TLD-100 measurement showed the average dose rate of 2.4 μSv/h; the neutron dosimeter gave the dose rate of 2.5 μSv/h. Comparing dose rates of the non-neutron component (low LET) and the neutron one (high LET) of the radiation field at the aircraft flight level, we could conclude that the neutron component carried about 50% of the total dose, that was near other known data

  6. Some cosmic radiation dose measurements aboard flights connecting Zagreb Airport

    Energy Technology Data Exchange (ETDEWEB)

    Vukovic, B.; Radolic, V. [Department of Physics, University of Osijek, Osijek, P.O. Box 125 (Croatia); Lisjak, I. [Croatia Airlines, Zagreb (Croatia); Vekic, B. [Rudjer Boskovic Institute, Zagreb (Croatia); Poje, M. [Department of Physics, University of Osijek, Osijek, P.O. Box 125 (Croatia); Planinic, J. [Department of Physics, University of Osijek, Osijek, P.O. Box 125 (Croatia)], E-mail: planinic@ffos.hr

    2008-02-15

    When primary particles from space, mainly protons, enter the atmosphere, they produce interactions with air nuclei, and cosmic-ray showers are induced. The radiation field at aircraft altitude is complex, with different types of particles, mainly photons, electrons, positrons and neutrons, with a large energy range. The non-neutron component of cosmic radiation dose aboard A320 and ATR40 aircraft was measured with TLD-100 (LiF:Mg,Ti) detectors and the Mini 6100 semiconductor dosimeter; the neutron dose was measured with the neutron dosimeter consisted of LR-115 track detector and boron foil BN-1 or {sup 10}B converter. The estimated occupational effective dose for the aircraft crew (A320) working 500 h per year was 1.64 mSv. Another experiment was performed at the flights Zagreb-Paris-Buenos Aires and reversely, when one measured non-neutron cosmic radiation dose; for 26.7 h of flight, the MINI 6100 dosimeter gave an average dose rate of 2.3 {mu}Sv/h and the TLD dosimeter registered the dose equivalent of 75 {mu}Sv or the average dose rate of 2.7 {mu}Sv/h; the neutron dosimeter gave the dose rate of 2.4 {mu}Sv/h. In the same month, February 2005, a traveling to Japan (24-h-flight: Zagreb-Frankfurt-Tokyo and reversely) and the TLD-100 measurement showed the average dose rate of 2.4 {mu}Sv/h; the neutron dosimeter gave the dose rate of 2.5 {mu}Sv/h. Comparing dose rates of the non-neutron component (low LET) and the neutron one (high LET) of the radiation field at the aircraft flight level, we could conclude that the neutron component carried about 50% of the total dose, that was near other known data.

  7. Verification of eye lens dose in IMRT by MOSFET measurement.

    Science.gov (United States)

    Wang, Xuetao; Li, Guangjun; Zhao, Jianling; Song, Ying; Xiao, Jianghong; Bai, Sen

    2018-04-17

    The eye lens is recognized as one of the most radiosensitive structures in the human body. The widespread use of intensity-modulated radiotherapy (IMRT) complicates dose verification and necessitates high standards of dose computation. The purpose of this work was to assess the computed dose accuracy of eye lens through measurements using a metal-oxide-semiconductor field-effect transistor (MOSFET) dosimetry system. Sixteen clinical IMRT plans of head and neck patients were copied to an anthropomorphic head phantom. Measurements were performed using the MOSFET dosimetry system based on the head phantom. Two MOSFET detectors were imbedded in the eyes of the head phantom as the left and the right lens, covered by approximately 5-mm-thick paraffin wax. The measurement results were compared with the calculated values with a dose grid size of 1 mm. Sixteen IMRT plans were delivered, and 32 measured lens doses were obtained for analysis. The MOSFET dosimetry system can be used to verify the lens dose, and our measurements showed that the treatment planning system used in our clinic can provide adequate dose assessment in eye lenses. The average discrepancy between measurement and calculation was 6.7 ± 3.4%, and the largest discrepancy was 14.3%, which met the acceptability criterion set by the American Association of Physicists in Medicine Task Group 53 for external beam calculation for multileaf collimator-shaped fields in buildup regions. Copyright © 2018 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.

  8. Application of combined TLD and CR-39 PNTD method for measurement of total dose and dose equivalent on ISS

    International Nuclear Information System (INIS)

    Benton, E.R.; Deme, S.; Apathy, I.

    2006-01-01

    To date, no single passive detector has been found that measures dose equivalent from ionizing radiation exposure in low-Earth orbit. We have developed the I.S.S. Passive Dosimetry System (P.D.S.), utilizing a combination of TLD in the form of the self-contained Pille TLD system and stacks of CR-39 plastic nuclear track detector (P.N.T.D.) oriented in three mutually orthogonal directions, to measure total dose and dose equivalent aboard the International Space Station (I.S.S.). The Pille TLD system, consisting on an on board reader and a large number of Ca 2 SO 4 :Dy TLD cells, is used to measure absorbed dose. The Pille TLD cells are read out and annealed by the I.S.S. crew on orbit, such that dose information for any time period or condition, e.g. for E.V.A. or following a solar particle event, is immediately available. Near-tissue equivalent CR-39 P.N.T.D. provides Let spectrum, dose, and dose equivalent from charged particles of LET ∞ H 2 O ≥ 10 keV/μm, including the secondaries produced in interactions with high-energy neutrons. Dose information from CR-39 P.N.T.D. is used to correct the absorbed dose component ≥ 10 keV/μm measured in TLD to obtain total dose. Dose equivalent from CR-39 P.N.T.D. is combined with the dose component <10 keV/μm measured in TLD to obtain total dose equivalent. Dose rates ranging from 165 to 250 μGy/day and dose equivalent rates ranging from 340 to 450 μSv/day were measured aboard I.S.S. during the Expedition 2 mission in 2001. Results from the P.D.S. are consistent with those from other passive detectors tested as part of the ground-based I.C.C.H.I.B.A.N. intercomparison of space radiation dosimeters. (authors)

  9. Measurements of the dose due to cosmic rays in aircraft

    International Nuclear Information System (INIS)

    Vukovic, B.; Lisjak, I.; Radolic, V.; Vekic, B.; Planinic, J.

    2006-01-01

    When the primary particles from space, mainly protons, enter the atmosphere, they produce interactions with air nuclei, and cosmic-ray showers are induced. The radiation field at aircraft altitude is complex, with different types of particles, mainly photons, electrons, positrons and neutrons, with a large energy range. The cosmic radiation dose aboard A320 and ATR 42 aircraft was measured with TLD-100 (LiF:Mg,Ti) detectors and the Mini 6100 semiconductor dosimeter; radon concentration in the atmosphere was measured with the Alpha Guard radon detector. The estimated occupational effective dose for the aircraft crew (A320) working 500 h per year was 1.64 mSv. Another experiment was performed by the flights Zagreb-Paris-Buenos Aires and reversely, when one measured cosmic radiation dose; for 26.7 h of flight, the TLD dosimeter registered the total dose of 75 μSv and the average dose rate was 2.7 μSv/h. In the same month, February 2005, a traveling to Japan (24 h flight: Zagreb-Frankfurt-Tokyo and reversely) and the TLD-100 measurement showed the average dose rate of 2.4 μSv/h

  10. Measurements of the dose due to cosmic rays in aircraft

    Energy Technology Data Exchange (ETDEWEB)

    Vukovic, B. [Department of Physics, University of Osijek, Osijek, P.O. Box 125 (Croatia); Lisjak, I. [Croatia Airlines, Zagreb (Croatia); Radolic, V. [Department of Physics, University of Osijek, Osijek, P.O. Box 125 (Croatia); Vekic, B. [Rudjer Boskovic Institute, Zagreb (Croatia); Planinic, J. [Department of Physics, University of Osijek, Osijek, P.O. Box 125 (Croatia)]. E-mail: planinic@ffos.hr

    2006-06-15

    When the primary particles from space, mainly protons, enter the atmosphere, they produce interactions with air nuclei, and cosmic-ray showers are induced. The radiation field at aircraft altitude is complex, with different types of particles, mainly photons, electrons, positrons and neutrons, with a large energy range. The cosmic radiation dose aboard A320 and ATR 42 aircraft was measured with TLD-100 (LiF:Mg,Ti) detectors and the Mini 6100 semiconductor dosimeter; radon concentration in the atmosphere was measured with the Alpha Guard radon detector. The estimated occupational effective dose for the aircraft crew (A320) working 500 h per year was 1.64 mSv. Another experiment was performed by the flights Zagreb-Paris-Buenos Aires and reversely, when one measured cosmic radiation dose; for 26.7 h of flight, the TLD dosimeter registered the total dose of 75 {mu}Sv and the average dose rate was 2.7 {mu}Sv/h. In the same month, February 2005, a traveling to Japan (24 h flight: Zagreb-Frankfurt-Tokyo and reversely) and the TLD-100 measurement showed the average dose rate of 2.4 {mu}Sv/h.

  11. Proton dose distribution measurements using a MOSFET detector with a simple dose-weighted correction method for LET effects.

    Science.gov (United States)

    Kohno, Ryosuke; Hotta, Kenji; Matsuura, Taeko; Matsubara, Kana; Nishioka, Shie; Nishio, Teiji; Kawashima, Mitsuhiko; Ogino, Takashi

    2011-04-04

    We experimentally evaluated the proton beam dose reproducibility, sensitivity, angular dependence and depth-dose relationships for a new Metal Oxide Semiconductor Field Effect Transistor (MOSFET) detector. The detector was fabricated with a thinner oxide layer and was operated at high-bias voltages. In order to accurately measure dose distributions, we developed a practical method for correcting the MOSFET response to proton beams. The detector was tested by examining lateral dose profiles formed by protons passing through an L-shaped bolus. The dose reproducibility, angular dependence and depth-dose response were evaluated using a 190 MeV proton beam. Depth-output curves produced using the MOSFET detectors were compared with results obtained using an ionization chamber (IC). Since accurate measurements of proton dose distribution require correction for LET effects, we developed a simple dose-weighted correction method. The correction factors were determined as a function of proton penetration depth, or residual range. The residual proton range at each measurement point was calculated using the pencil beam algorithm. Lateral measurements in a phantom were obtained for pristine and SOBP beams. The reproducibility of the MOSFET detector was within 2%, and the angular dependence was less than 9%. The detector exhibited a good response at the Bragg peak (0.74 relative to the IC detector). For dose distributions resulting from protons passing through an L-shaped bolus, the corrected MOSFET dose agreed well with the IC results. Absolute proton dosimetry can be performed using MOSFET detectors to a precision of about 3% (1 sigma). A thinner oxide layer thickness improved the LET in proton dosimetry. By employing correction methods for LET dependence, it is possible to measure absolute proton dose using MOSFET detectors.

  12. Measurement of absorbed dose with a bone-equivalent extrapolation chamber

    International Nuclear Information System (INIS)

    DeBlois, Francois; Abdel-Rahman, Wamied; Seuntjens, Jan P.; Podgorsak, Ervin B.

    2002-01-01

    A hybrid phantom-embedded extrapolation chamber (PEEC) made of Solid Water trade mark sign and bone-equivalent material was used for determining absorbed dose in a bone-equivalent phantom irradiated with clinical radiation beams (cobalt-60 gamma rays; 6 and 18 MV x rays; and 9 and 15 MeV electrons). The dose was determined with the Spencer-Attix cavity theory, using ionization gradient measurements and an indirect determination of the chamber air-mass through measurements of chamber capacitance. The collected charge was corrected for ionic recombination and diffusion in the chamber air volume following the standard two-voltage technique. Due to the hybrid chamber design, correction factors accounting for scatter deficit and electrode composition were determined and applied in the dose equation to obtain absorbed dose in bone for the equivalent homogeneous bone phantom. Correction factors for graphite electrodes were calculated with Monte Carlo techniques and the calculated results were verified through relative air cavity dose measurements for three different polarizing electrode materials: graphite, steel, and brass in conjunction with a graphite collecting electrode. Scatter deficit, due mainly to loss of lateral scatter in the hybrid chamber, reduces the dose to the air cavity in the hybrid PEEC in comparison with full bone PEEC by 0.7% to ∼2% depending on beam quality and energy. In megavoltage photon and electron beams, graphite electrodes do not affect the dose measurement in the Solid Water trade mark sign PEEC but decrease the cavity dose by up to 5% in the bone-equivalent PEEC even for very thin graphite electrodes (<0.0025 cm). In conjunction with appropriate correction factors determined with Monte Carlo techniques, the uncalibrated hybrid PEEC can be used for measuring absorbed dose in bone material to within 2% for high-energy photon and electron beams

  13. SU-E-J-198: Out-Of-Field Dose and Surface Dose Measurements of MRI-Guided Cobalt-60 Radiotherapy

    International Nuclear Information System (INIS)

    Lamb, J; Agazaryan, N; Cao, M; Low, D; Thomas, D; Yang, Y

    2015-01-01

    Purpose: To measure quantities of dosimetric interest in an MRI-guided cobalt radiotherapy machine that was recently introduced to clinical use. Methods: Out-of-field dose due to photon scatter and leakage was measured using an ion chamber and solid water slabs mimicking a human body. Surface dose was measured by irradiating stacks of radiochromic film and extrapolating to zero thickness. Electron out-of-field dose was characterized using solid water slabs and radiochromic film. Results: For some phantom geometries, up to 50% of Dmax was observed up to 10 cm laterally from the edge of the beam. The maximum penetration was between 1 and 2 mm in solid water, indicating an electron energy not greater than approximately 0.4 MeV. Out-of-field dose from photon scatter measured at 1 cm depth in solid water was found to fall to less than 10% of Dmax at a distance of 1.2 cm from the edge of a 10.5 × 10.5 cm field, and less that 1% of Dmax at a distance of 10 cm from field edge. Surface dose was measured to be 8% of Dmax. Conclusion: Surface dose and out-of-field dose from the MRIguided cobalt radiotherapy machine was measured and found to be within acceptable limits. Electron out-of-field dose, an effect unique to MRI-guided radiotherapy and presumed to arise from low-energy electrons trapped by the Lorentz force, was quantified. Dr. Low is a member of the scientific advisory board of ViewRay, Inc

  14. Analytical evaluation of dose measurement of critical accident at SILENE (Contract research)

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, Takemi; Tonoike, Kotaro; Miyoshi, Yoshinori [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2003-03-01

    Institute for Radioprotection and Nuclear Safety (IRSN) and the OECD Nuclear Energy Agency (NEA) jointly organized SILENE Accident Dosimetry Intercomparison Exercise to intercompare the dose measurement systems of participating countries. Each participating country carried out dose measurements in the same irradiation field, and the measurement results were mutually compared. The authors participated in the exercise to measure the doses of gamma rays and neutron from SILENE by using thermoluminescence dosimeters (TLD's) and an alanine dosimeter. In this examination, the authors derived evaluation formulae for obtaining a tissue-absorbed dose from measured value (ambient dose equivalent) of TLD for neutron. We reported the tissue-absorbed dose computed using this evaluation formula to OECD/NEA. TLD's for neutron were irradiated in the TRACY facility to verify the evaluation formulae. The results of TLD's were compared with the calculations of MCNP and measurements with alanine dose meter. We found that the ratio of the dose by the evaluation formula to the measured value by the alanine dosimeter was 0.94 and the formula agreed within 6%. From examination of this TRACY, we can conclude that the value reported to OECD/NEA has equivalent accuracy. (author)

  15. Measurement of annual dose on porcelain using surface TLD method

    International Nuclear Information System (INIS)

    Xia Junding; Wang Weida; Leung, P.L.

    2001-01-01

    In order to improve accuracy of TL authentication test for porcelain, a method of measurement of annual dose using ultrathin (CaSO 4 :Tm) dosage layer on porcelain was studied. The TLD was placed on the part of porcelain without glaze. A comparison of measurement of annual dose for surface TLD, inside TLD and alpha counting on porcelain was made. The results show that this technique is suitable for measuring annual dose and improving accuracy of TL authentication test for both porcelain and pottery

  16. TLD array for precise dose measurements in stereotactic radiation techniques

    International Nuclear Information System (INIS)

    Ertl, A.; Kitz, K.; Griffitt, W.; Hartl, R.F.E.; Zehetmayer, M.

    1996-01-01

    We developed a new TLD array for precise dose measurement and verification of the spatial dose distribution in small radiation targets. It consists of a hemicylindrical, tissue-equivalent rod made of polystyrene with 17 parallel moulds for an exact positioning of each TLD. The spatial resolution of the TLD array was evaluated using the Leskell spherical phantom. Dose planning was performed with KULA 4.4 under stereotactic conditions on axial CT images. In the Leksell gamma unit the TLD array was irradiated with a maximal dose of 10 Gy with an unplugged 14 mm collimator. The doses delivered to the TLDs were rechecked by diode detector and film dosimetry and compared to the computer-generated dose profile. We found excellent agreement of our measured values, even at the critical penumbra decline. For the 14 mm and 18 mm collimator and for the 11 mm collimator combination we compared the measured and calculated data at full width at half maximum. This TLD array may be useful for phantom or tissue model studies on the spatial dose distribution in confined radiation targets as used in stereotactic radiotherapy. (author)

  17. High-temperature absorbed dose measurements in the megagray range

    International Nuclear Information System (INIS)

    Balian, P.; Ardonceau, J.; Zuppiroli, L.

    1988-01-01

    Organic conductors of the tetraselenotetracene family have been tested as ''high-temperature'' absorbed dose dosimeters. They were heated up to 120 0 C and irradiated at this temperature with 1-MeV electrons in order to simulate, in a short time, a much longer γ-ray irradiation. The electric resistance increase of the crystal can be considered a good measurement of the absorbed dose in the range 10 6 Gy to a few 10 8 Gy and presumably one order of magnitude more. This dosimeter also permits on-line (in-situ) measurements of the absorbed dose without removing the sensor from the irradiation site. The respective advantages of organic and inorganic dosimeters at these temperature and dose ranges are also discussed. In this connection, we outline new, but negative, results concerning the possible use of silica as a high-temperature, high-dose dosimeter. (author)

  18. Effects of acute chlorpyrifos exposure on in vivo acetylcholine accumulation in rat striatum

    International Nuclear Information System (INIS)

    Karanth, Subramanya; Liu, Jing; Mirajkar, Nikita; Pope, Carey

    2006-01-01

    This study examined the acute effects of chlorpyrifos (CPF) on cholinesterase inhibition and acetylcholine levels in the striatum of freely moving rats using in vivo microdialysis. Adult, male Sprague-Dawley rats were treated with vehicle (peanut oil, 2 ml/kg) or CPF (84, 156 or 279 mg/kg, sc) and functional signs of toxicity, body weight and motor activity recorded. Microdialysis was conducted at 1, 4 and 7 days after CPF exposure for measurement of acetylcholine levels in striatum. Rats were then sacrificed and the contralateral striatum and diaphragm were collected for biochemical measurements. Few overt signs of cholinergic toxicity were noted in any rats. Body weight gain was significantly affected in the high-dose (279 mg/kg) group only, while motor activity (nocturnal rearing) was significantly reduced in all CPF-treated groups at one day (84 mg/kg) or from 1-4 days (156 and 279 mg/kg) after dosing. Cholinesterase activities in both diaphragm and striatum were markedly inhibited (50-92%) in a time-dependent manner, but there were relatively minimal dose-related changes. In contrast, time- and dose-dependent changes in striatal acetylcholine levels were noted, with significantly higher levels noted in the high-dose group compared to other groups. Maximal increases in striatal acetylcholine levels were observed at 4-7 days after dosing (84 mg/kg, 7-9-fold; 156 mg/kg, 10-13-fold; 279 mg/kg, 35-57-fold). Substantially higher acetylcholine levels were noted when an exogenous cholinesterase inhibitor was included in the perfusion buffer, but CPF treatment-related differences were substantially lower in magnitude under those conditions. The results suggest that marked differences in acetylcholine accumulation can occur with dosages of CPF eliciting relatively similar degrees of cholinesterase inhibition. Furthermore, the minimal expression of classic signs of cholinergic toxicity in the presence of extensive brain acetylcholine accumulation suggests that some

  19. MO-C-17A-11: A Segmentation and Point Matching Enhanced Deformable Image Registration Method for Dose Accumulation Between HDR CT Images

    International Nuclear Information System (INIS)

    Zhen, X; Chen, H; Zhou, L; Yan, H; Jiang, S; Jia, X; Gu, X; Mell, L; Yashar, C; Cervino, L

    2014-01-01

    Purpose: To propose and validate a novel and accurate deformable image registration (DIR) scheme to facilitate dose accumulation among treatment fractions of high-dose-rate (HDR) gynecological brachytherapy. Method: We have developed a method to adapt DIR algorithms to gynecologic anatomies with HDR applicators by incorporating a segmentation step and a point-matching step into an existing DIR framework. In the segmentation step, random walks algorithm is used to accurately segment and remove the applicator region (AR) in the HDR CT image. A semi-automatic seed point generation approach is developed to obtain the incremented foreground and background point sets to feed the random walks algorithm. In the subsequent point-matching step, a feature-based thin-plate spline-robust point matching (TPS-RPM) algorithm is employed for AR surface point matching. With the resulting mapping, a DVF characteristic of the deformation between the two AR surfaces is generated by B-spline approximation, which serves as the initial DVF for the following Demons DIR between the two AR-free HDR CT images. Finally, the calculated DVF via Demons combined with the initial one serve as the final DVF to map doses between HDR fractions. Results: The segmentation and registration accuracy are quantitatively assessed by nine clinical HDR cases from three gynecological cancer patients. The quantitative results as well as the visual inspection of the DIR indicate that our proposed method can suppress the interference of the applicator with the DIR algorithm, and accurately register HDR CT images as well as deform and add interfractional HDR doses. Conclusions: We have developed a novel and robust DIR scheme that can perform registration between HDR gynecological CT images and yield accurate registration results. This new DIR scheme has potential for accurate interfractional HDR dose accumulation. This work is supported in part by the National Natural ScienceFoundation of China (no 30970866 and no

  20. Clinical application of a OneDose MOSFET for skin dose measurements during internal mammary chain irradiation with high dose rate brachytherapy in carcinoma of the breast.

    Science.gov (United States)

    Kinhikar, Rajesh A; Sharma, Pramod K; Tambe, Chandrashekhar M; Mahantshetty, Umesh M; Sarin, Rajiv; Deshpande, Deepak D; Shrivastava, Shyam K

    2006-07-21

    In our earlier study, we experimentally evaluated the characteristics of a newly designed metal oxide semiconductor field effect transistor (MOSFET) OneDose in-vivo dosimetry system for Ir-192 (380 keV) energy and the results were compared with thermoluminescent dosimeters (TLDs). We have now extended the same study to the clinical application of this MOSFET as an in-vivo dosimetry system. The MOSFET was used during high dose rate brachytherapy (HDRBT) of internal mammary chain (IMC) irradiation for a carcinoma of the breast. The aim of this study was to measure the skin dose during IMC irradiation with a MOSFET and a TLD and compare it with the calculated dose with a treatment planning system (TPS). The skin dose was measured for ten patients. All the patients' treatment was planned on a PLATO treatment planning system. TLD measurements were performed to compare the accuracy of the measured results from the MOSFET. The mean doses measured with the MOSFET and the TLD were identical (0.5392 Gy, 15.85% of the prescribed dose). The mean dose was overestimated by the TPS and was 0.5923 Gy (17.42% of the prescribed dose). The TPS overestimated the skin dose by 9% as verified by the MOSFET and TLD. The MOSFET provides adequate in-vivo dosimetry for HDRBT. Immediate readout after irradiation, small size, permanent storage of dose and ease of use make the MOSFET a viable alternative for TLDs.

  1. Energy and energy width measurement in the FNAL antiproton accumulator

    International Nuclear Information System (INIS)

    Church, M.; Hsueh, S.; Rapidis, P.; Werkema, S.

    1991-10-01

    The Fermilab Antiproton Accumulator has recently been used to produce Charmonium resonances (charm quark, anti-charm quark bound states) in proton-antiproton annihilations using an internal H 2 gas jet target. A measurement of the resonance mass and width may be obtained from a precise knowledge of the antiproton beam energy and energy spread. The beam energy is measured to an accuracy of 1 part in 10 4 in the range 6.3 Gev to 4.1 Gev by measuring the orbit length and revolution frequency of the beam. The beam momentum spread is measured to an accuracy of 10% by measuring the beam frequency spread and the parameter η = (P beam /F rev )·(dF rev /dP beam ). These two measurement techniques are described in this report

  2. Comparison of dose measurements in water versus in air for therapy

    International Nuclear Information System (INIS)

    Nasukha

    1987-01-01

    Comparison of dose measurements in water versus in air for therapy. Dose measurements in water and in the air had been done by teletherapy unit Co-60 Picker Model V 4m/60 with Farmer dosimeter. The result of inverse square law, TAR, PDD, and PSF compared to BJR No. 17 produced a difference of more than 4,65% with SSD 80 cm. Doses in water calculated from the result of dose measurement in air using BJR tables given, was compared with direct dose measurement in water. Values of 0,9850 to 1,0302 were obtained if using inverse square law, PDD and PSF formula. Using inverse square law and TAR, values of 0,9474 to 1,0197 were obtained for 4 depths and 5 field sizes. Measurements done in 5 cm depth and 10 cm x 10 cm field size using both methods, were still good. (author). 7 figs, 8 refs

  3. Cosmic-ray contribution in measurement of environmental gamma-ray dose

    International Nuclear Information System (INIS)

    Nagaoka, Kazunori; Honda, Kouichirou; Miyano, Keiji

    1996-01-01

    Nowadays several kinds of dosimeters are being used for environmental gamma-ray monitoring. However the results measured by those instruments are not always in good agreement. It may be caused from the different characteristics of dosimeters. In particular the different responses of the instruments to cosmic-rays give significant influence on the results. Environmental radiation measurements at various altitudes on Mt. Fuji were carried out using a scintillation spectrometer with 3''φ spherical NaI(Tl), a pressurized ionization chamber (PIC), an air-equivalent ionization chamber (IC), thermoluminescence dosimeters (TLD), radiophotoluminescence glass dosimeters (RPLD) and NaI(Tl) scintillation survey meters so that the response characteristics of these instruments to cosmic-rays could be clarified. Cosmic-ray contributions for all instruments were correlated with counting rate over 3 MeV by the spectrometer. Each contribution can be estimated by measurement of the counting rate. Conversion factors (nGy/h/cpm) for IC, PIC, TLD, RPLD and NaI survey meters (TCS166 and TCS121C) were 0.33, 0.32, 0.25, 0.24, 0.06 and -0.01, respectively. Self-doses of these instruments were estimated by measurements at Nokogiriyama facilities of the Institute for Cosmic Ray Research, University of Tokyo. Self-doses for TLD and RPLD were approximately 6 nGy/h. The self dose effect should be taken into consideration in environmental dose measurements. These data are expected to be useful in estimating the cosmic-ray contribution and self-dose in the measurement of environmental gamma-ray dose. (author)

  4. Measurements of the Chernobyl accident fallout in Israel and the assessment of the radiation doses to the population

    Energy Technology Data Exchange (ETDEWEB)

    Stern, E; Ilberg, D [Israel Atomic Energy Commission, Beer-Sheva, Negev (Israel); Brenner, S [Ministry of Environment, Yerusalem (Israel); and others

    1997-09-01

    Israel is located approximately 2000 km southeast of Chernobyl. The fallout from the accident in Chernobyl reactor no. 4 on April 26, 1986 arrived in Israel on the night of May 2nd. Following the accident, studies of the radiological effects were initiated by many countries some of them many thousands of kilometers away. These studies can be characterized by three periods: a) First months following the accident - Measurements were taken to assess the immediate impact and to propose countermeasures that would reduce doses incurred by the population. b) First years following the accidents - Measurements were taken to validate that radioecological effects are well below any regulatory limits, from both the fallout radioactivity in the country and import of food coming from other affected areas. c) The last years (e.g. 1990-1995) - Measurements were taken within the regular program of environmental radioactivity surveillance. In this paper we have compiled the results of the studies in Israel which have followed the three phases mentioned above. Assessment of the accumulated potential radiation doses to the population in Israel was made based on the results of those measurements covered in the three phases, considering the various possible pathways. 7 refs, 1 fig., 5 tabs.

  5. Comparison of measured and calculated doses for narrow MLC defined fields

    International Nuclear Information System (INIS)

    Lydon, J.; Rozenfeld, A.; Lerch, M.

    2002-01-01

    Full text: The introduction of Intensity Modulated Radiotherapy (IMRT) has led to the use of narrow fields in the delivery of radiation doses to patients. Such fields are not well characterized by calculation methods commonly used in radiotherapy treatment planning systems. The accuracy of the dose calculation algorithm must therefore be investigated prior to clinical use. This study looked at symmetrical and asymmetrical 0.1 to 3cm wide fields delivered with a Varian CL2100C 6MV photon beam. Measured doses were compared to doses calculated using Pinnacle, the ADAC radiotherapy treatment planning system. Two high resolution methods of measuring dose were used. A MOSFET detector in a water phantom and radiographic film in a solid water phantom with spatial resolutions of 10 and 89μm respectively. Dose calculations were performed using the collapsed cone convolution algorithm in Pinnacle with a 0.1cm dose calculation grid in the MLC direction. The effect of Pinnacle not taking into account the rounded leaf ends was simulated by offsetting the leaves by 0.1cm in the dose calculation. Agreement between measurement and calculation is good for fields of 1cm and wider. However, fields of less than 1cm width can show a significant difference between measurement and calculation

  6. SU-G-BRB-14: Uncertainty of Radiochromic Film Based Relative Dose Measurements

    Energy Technology Data Exchange (ETDEWEB)

    Devic, S; Tomic, N; DeBlois, F; Seuntjens, J [McGill University, Montreal, QC (Canada); Lewis, D [RCF Consulting, LLC, Monroe, CT (United States); Aldelaijan, S [King Faisal Specialist Hospital & Research Center, Riyadh (Saudi Arabia)

    2016-06-15

    Purpose: Due to inherently non-linear dose response, measurement of relative dose distribution with radiochromic film requires measurement of absolute dose using a calibration curve following previously established reference dosimetry protocol. On the other hand, a functional form that converts the inherently non-linear dose response curve of the radiochromic film dosimetry system into linear one has been proposed recently [Devic et al, Med. Phys. 39 4850–4857 (2012)]. However, there is a question what would be the uncertainty of such measured relative dose. Methods: If the relative dose distribution is determined going through the reference dosimetry system (conversion of the response by using calibration curve into absolute dose) the total uncertainty of such determined relative dose will be calculated by summing in quadrature total uncertainties of doses measured at a given and at the reference point. On the other hand, if the relative dose is determined using linearization method, the new response variable is calculated as ζ=a(netOD)n/ln(netOD). In this case, the total uncertainty in relative dose will be calculated by summing in quadrature uncertainties for a new response function (σζ) for a given and the reference point. Results: Except at very low doses, where the measurement uncertainty dominates, the total relative dose uncertainty is less than 1% for the linear response method as compared to almost 2% uncertainty level for the reference dosimetry method. The result is not surprising having in mind that the total uncertainty of the reference dose method is dominated by the fitting uncertainty, which is mitigated in the case of linearization method. Conclusion: Linearization of the radiochromic film dose response provides a convenient and a more precise method for relative dose measurements as it does not require reference dosimetry and creation of calibration curve. However, the linearity of the newly introduced function must be verified. Dave Lewis

  7. Prototype development or multi-cavity ion chamber for depth dose measurement

    International Nuclear Information System (INIS)

    Nayak, M.K.; Sahu, T.K.; Haridas, G.; Bandyopadhyay, Tapas; Tripathi, R.M.; Nandedkar, R.V.

    2016-01-01

    In high energy electron accelerators, when the electrons interact with vacuum chamber or surrounding structural material, Bremsstrahlung x-rays are produced. It is having a broad spectrum extending up to the electron energies. Dose measured as a function of depth due to electromagnetic cascade will give rise to depth dose curve. To measure the online depth dose profile in an absorber medium, when high energy electron or Bremsstrahlung is incident, a prototype Multi-Cavity Ion Chamber (MCIC) detector is developed. The paper describes the design and development of the MCIC for measurement of depth dose profile

  8. Dental radiography: tooth enamel EPR dose assessment from Rando phantom measurements

    International Nuclear Information System (INIS)

    Aragno, D.; Fattibene, P.; Onori, S.

    2000-01-01

    Electron paramagnetic resonance dosimetry of tooth enamel is now established as a suitable method for individual dose reconstruction following radiation accidents. The accuracy of the method is limited by some confounding factors, among which is the dose received due to medical x-ray irradiation. In the present paper the EPR response of tooth enamel to endoral examination was experimentally evaluated using an anthropomorphic phantom. The dose to enamel for a single exposure of a typical dental examination performed with a new x-ray generation unit working at 65 kVp gave rise to a CO 2 -signal of intensity similar to that induced by a dose of about 2 mGy of 60 Co. EPR measurements were performed on the entire tooth with no attempt to separate buccal and lingual components. Also the dose to enamel for an orthopantomography exam was estimated. It was derived from TLD measurements as equivalent to 0.2 mGy of 60 Co. In view of application to risk assessment analysis, in the present work the value for the ratio of the reference dose at the phantom surface measured with TLD to the dose at the tooth measured with EPR was determined. (author)

  9. Radiation dose to surgeons in theatre | van der Merwe | South ...

    African Journals Online (AJOL)

    Thermoluminescent dosimeter measurements of accumulated dose to specific anatomical regions of a neurosurgeon, gastroenterologist and orthopaedic surgeon performing fluoroscopy on 39 patients undergoing treatment for back pain, 7 for endoscopic retrograde cholangiopancreatography procedures, and 48 for ...

  10. Imaging and Measuring Electron Beam Dose Distributions Using Holographic Interferometry

    DEFF Research Database (Denmark)

    Miller, Arne; McLaughlin, W. L.

    1975-01-01

    Holographic interferometry was used to image and measure ionizing radiation depth-dose and isodose distributions in transparent liquids. Both broad and narrowly collimated electron beams from accelerators (2–10 MeV) provided short irradiation times of 30 ns to 0.6 s. Holographic images...... and measurements of absorbed dose distributions were achieved in liquids of various densities and thermal properties and in water layers thinner than the electron range and with backings of materials of various densities and atomic numbers. The lowest detectable dose in some liquids was of the order of a few k......Rad. The precision limits of the measurement of dose were found to be ±4%. The procedure was simple and the holographic equipment stable and compact, thus allowing experimentation under routine laboratory conditions and limited space....

  11. Oblique incidence of electron beams - comparisons between calculated and measured dose distributions

    International Nuclear Information System (INIS)

    Karcher, J.; Paulsen, F.; Christ, G.

    2005-01-01

    Clinical applications of high-energy electron beams, for example for the irradiation of internal mammary lymph nodes, can lead to oblique incidence of the beams. It is well known that oblique incidence of electron beams can alter the depth dose distribution as well as the specific dose per monitor unit. The dose per monitor unit is the absorbed dose in a point of interest of a beam, which is reached with a specific dose monitor value (DIN 6814-8[5]). Dose distribution and dose per monitor unit at oblique incidence were measured with a small-volume thimble chamber in a water phantom, and compared to both normal incidence and calculations of the Helax TMS 6.1 treatment planning system. At 4 MeV and 60 degrees, the maximum measured dose per monitor unit at oblique incidence was decreased up to 11%, whereas at 18MeV and 60 degrees this was increased up to 15% compared to normal incidence. Comparisons of measured and calculated dose distributions showed that the predicted dose at shallow depths is usually higher than the measured one, whereas it is smaller at depths beyond the depth of maximum dose. On the basis of the results of these comparisons, normalization depths and correction factors for the dose monitor value were suggested to correct the calculations of the dose per monitor unit. (orig.)

  12. Technical specification of the NRPB thermoluminescent dosemeter used for the measurement of body dose and skin dose

    CERN Document Server

    Shaw, K B

    1977-01-01

    This report specifies the NRPB thermoluminescent dosemeter used for the measurement of radiation dose in tissue at a depth of 700 mg cm sup - sup 2 (body dose) and at a depth of 5-10 mg cm sup - sup 2 (skin dose).

  13. Measurement and evaluation of internal dose

    International Nuclear Information System (INIS)

    Lee, Tae Young; Chang, S. Y.; Lee, J. I.; Song, M. Y.

    2006-01-01

    This report describes the contents and results for implementation of internal radiation monitoring programme, measurement of uranium present in lung by lung counter and assessment of committed effective dose for radiation workers of the KNFC. The aim of radiation protection was achieved by implementing this activity

  14. First Results from the Online Radiation Dose Monitoring System in ATLAS experiment

    CERN Document Server

    Mandić, I; The ATLAS collaboration; Deliyergiyev, M; Gorišek, A; Kramberger, G; Mikuž, M; Franz, S; Hartert, J; Dawson, I; Miyagawa, P S; Nicolas, L

    2011-01-01

    High radiation doses which will accumulate in components of ATLAS experiment during data taking will cause damage to detectors and readout electronics. It is therefore important to continuously monitor the doses to estimate the level of degradation caused by radiation. Online radiation monitoring system measures ionizing dose in SiO2 and fluences of 1-MeV(Si) equivalent neutrons and thermal neutrons at several locations in ATLAS detector. In this paper measurements collected during two years of ATLAS data taking are presented and compared to predictions from radiation background simulations.

  15. Rapid Measurement of Neutron Dose Rate for Transport Index

    International Nuclear Information System (INIS)

    Morris, R.L.

    2000-01-01

    A newly available neutron dose equivalent remmeter with improved sensitivity and energy response has been put into service at Rocky Flats Environmental Technology Site (RFETS). This instrument is being used to expedite measurement of the Transport Index and as an ALARA tool to identify locations where slightly elevated neutron dose equivalent rates exist. The meter is capable of measuring dose rates as low as 0.2 μSv per hour (20 μrem per hour). Tests of the angular response and energy response of the instrument are reported. Calculations of the theoretical instrument response made using MCNPtrademark are reported for materials typical of those being shipped

  16. Eye lens dosimetry in interventional cardiology: Results of staff dose measurements and link to patient dose levels

    International Nuclear Information System (INIS)

    Antic, V.; Ciraj-Bjelac, O.; Rehani, M.; Aleksandric, S.; Arandjic, D.; Ostojic, M.

    2013-01-01

    Workers involved in interventional cardiology procedures receive high eye lens dose if protection is not used. Currently, there is no suitable method for routine use for the measurement of eye dose. Since most angiography machines are equipped with suitable patient dosemeters, deriving factors linking staff eye doses to the patient doses can be helpful. In this study the patient kerma-area product, cumulative dose at an interventional reference point and eye dose in terms of Hp(3) of the cardiologists, nurses and radiographers for interventional cardiology procedures have been measured. Correlations between the patient dose and the staff eye dose were obtained. The mean eye dose was 121 mSv for the first operator, 33 mSv for the second operator/nurse and 12 mSv for radiographer. Normalised eye lens doses per unit kerma-area product were 0.94 mSv Gy -1 cm -2 for the first operator, 0.33 mSv Gy -1 cm -2 for the second operator/nurse and 0.16 mSv Gy -1 cm -2 for radiographers. Statistical analysis indicated that there is a weak but significant (p < 0.01) correlation between the eye dose and the kerma-area product for all three staff categories. These values are based on a local practice and may provide useful reference for other studies for validation and for wider utilisation in assessing the eye dose using patient dose values. (authors)

  17. Dose measurement, its distribution and individual external dose assessments of inhabitants on high background radiation area in China

    Energy Technology Data Exchange (ETDEWEB)

    Koga, Taeko; Morishima, Hiroshige [Kinki Univ., Atomic Energy Research Institute, Osaka (Japan); Tatsumi, Kusuo [Kinki Univ., Life Science Research Institute, Osaka (Japan); Nakai, Sayaka; Sugahara, Tsutomu [Health Research Foundation, Kyoto (Japan); Yuan Yongling [Labor Hygiene Institute of Hunan Prov. (China); Wei Luxin [Laboratory of Industorial Hygiene, Ministry of Health (China)

    2001-01-01

    As a part of the China-Japan cooperative research on the natural radiation epidemiology, we have carried out a dose-assessment study to evaluate the external to natural radiation in the high background radiation area (HBRA) of Yangjiang in Guangdong province and in the control area (CA) of Enping prefecture since 1991. Because of the difficulties in measuring the individual doses of all inhabitants directly by the personal dosimeters, an indirect method was applied to estimate the exposed dose rates from the environmental radiation dose rates measured by survey meters and the occupancy factors of each hamlet. An individual radiation dose roughly correlates with the environmental radiation dose and the life style of the inhabitant. We have analyzed the environmental radiation doses in the hamlets and the variation of the occupancy factors to obtain the parameters of dose estimation on the inhabitants in selected hamlets; Madi and the several hamlets of the different level doses in HBRA and Hampizai hamlet in CA. With these parameters, we made estimations of individual dose rates and compared them with those obtained from the direct measurement using dosimeters carried by selected individuals. The results obtained are as follows: (1) The environmental radiation dose rates are influenced by the natural radioactive nuclide concentrations in building materials, the age of the building and the arrangement of the houses in a hamlet. There existed a fairly large and heterogeneous distribution of indoor and outdoor environmental radiation. The indoor radiation dose rates were due to the exposure from the natural radioactive nuclides in the building materials and they were about twice higher than the outdoor radiation dose rates. This difference was not observed in CA. (2) The occupancy factor was affected by the age of individuals and the seasons of a year. Indoor occupancy factors were higher for infants and aged individuals than for other age groups. This lead to higher

  18. Dose measurement, its distribution and individual external dose assessments of inhabitants on high background radiation area in China

    International Nuclear Information System (INIS)

    Koga, Taeko; Morishima, Hiroshige; Tatsumi, Kusuo; Nakai, Sayaka; Sugahara, Tsutomu; Yuan Yongling; Wei Luxin

    2001-01-01

    As a part of the China-Japan cooperative research on the natural radiation epidemiology, we have carried out a dose-assessment study to evaluate the external to natural radiation in the high background radiation area (HBRA) of Yangjiang in Guangdong province and in the control area (CA) of Enping prefecture since 1991. Because of the difficulties in measuring the individual doses of all inhabitants directly by the personal dosimeters, an indirect method was applied to estimate the exposed dose rates from the environmental radiation dose rates measured by survey meters and the occupancy factors of each hamlet. An individual radiation dose roughly correlates with the environmental radiation dose and the life style of the inhabitant. We have analyzed the environmental radiation doses in the hamlets and the variation of the occupancy factors to obtain the parameters of dose estimation on the inhabitants in selected hamlets; Madi and the several hamlets of the different level doses in HBRA and Hampizai hamlet in CA. With these parameters, we made estimations of individual dose rates and compared them with those obtained from the direct measurement using dosimeters carried by selected individuals. The results obtained are as follows: 1) The environmental radiation dose rates are influenced by the natural radioactive nuclide concentrations in building materials, the age of the building and the arrangement of the houses in a hamlet. There existed a fairly large and heterogeneous distribution of indoor and outdoor environmental radiation. The indoor radiation dose rates were due to the exposure from the natural radioactive nuclides in the building materials and they were about twice higher than the outdoor radiation dose rates. This difference was not observed in CA. 2) The occupancy factor was affected by the age of individuals and the seasons of a year. Indoor occupancy factors were higher for infants and aged individuals than for other age groups. This lead to higher

  19. Clinical application of a OneDose(TM) MOSFET for skin dose measurements during internal mammary chain irradiation with high dose rate brachytherapy in carcinoma of the breast

    International Nuclear Information System (INIS)

    Kinhikar, Rajesh A; Sharma, Pramod K; Tambe, Chandrashekhar M; Mahantshetty, Umesh M; Sarin, Rajiv; Deshpande, Deepak D; Shrivastava, Shyam K

    2006-01-01

    In our earlier study, we experimentally evaluated the characteristics of a newly designed metal oxide semiconductor field effect transistor (MOSFET) OneDose(TM) in-vivo dosimetry system for Ir-192 (380 keV) energy and the results were compared with thermoluminescent dosimeters (TLDs). We have now extended the same study to the clinical application of this MOSFET as an in-vivo dosimetry system. The MOSFET was used during high dose rate brachytherapy (HDRBT) of internal mammary chain (IMC) irradiation for a carcinoma of the breast. The aim of this study was to measure the skin dose during IMC irradiation with a MOSFET and a TLD and compare it with the calculated dose with a treatment planning system (TPS). The skin dose was measured for ten patients. All the patients' treatment was planned on a PLATO treatment planning system. TLD measurements were performed to compare the accuracy of the measured results from the MOSFET. The mean doses measured with the MOSFET and the TLD were identical (0.5392 Gy, 15.85% of the prescribed dose). The mean dose was overestimated by the TPS and was 0.5923 Gy (17.42% of the prescribed dose). The TPS overestimated the skin dose by 9% as verified by the MOSFET and TLD. The MOSFET provides adequate in-vivo dosimetry for HDRBT. Immediate readout after irradiation, small size, permanent storage of dose and ease of use make the MOSFET a viable alternative for TLDs. (note)

  20. A segmentation and point-matching enhanced efficient deformable image registration method for dose accumulation between HDR CT images

    International Nuclear Information System (INIS)

    Zhen, Xin; Chen, Haibin; Zhou, Linghong; Yan, Hao; Jiang, Steve; Jia, Xun; Gu, Xuejun; Mell, Loren K; Yashar, Catheryn M; Cervino, Laura

    2015-01-01

    Deformable image registration (DIR) of fractional high-dose-rate (HDR) CT images is challenging due to the presence of applicators in the brachytherapy image. Point-to-point correspondence fails because of the undesired deformation vector fields (DVF) propagated from the applicator region (AR) to the surrounding tissues, which can potentially introduce significant DIR errors in dose mapping. This paper proposes a novel segmentation and point-matching enhanced efficient DIR (named SPEED) scheme to facilitate dose accumulation among HDR treatment fractions. In SPEED, a semi-automatic seed point generation approach is developed to obtain the incremented fore/background point sets to feed the random walks algorithm, which is used to segment and remove the AR, leaving empty AR cavities in the HDR CT images. A feature-based ‘thin-plate-spline robust point matching’ algorithm is then employed for AR cavity surface points matching. With the resulting mapping, a DVF defining on each voxel is estimated by B-spline approximation, which serves as the initial DVF for the subsequent Demons-based DIR between the AR-free HDR CT images. The calculated DVF via Demons combined with the initial one serve as the final DVF to map doses between HDR fractions. The segmentation and registration accuracy are quantitatively assessed by nine clinical HDR cases from three gynecological cancer patients. The quantitative analysis and visual inspection of the DIR results indicate that SPEED can suppress the impact of applicator on DIR, and accurately register HDR CT images as well as deform and add interfractional HDR doses. (paper)

  1. A segmentation and point-matching enhanced efficient deformable image registration method for dose accumulation between HDR CT images

    Science.gov (United States)

    Zhen, Xin; Chen, Haibin; Yan, Hao; Zhou, Linghong; Mell, Loren K.; Yashar, Catheryn M.; Jiang, Steve; Jia, Xun; Gu, Xuejun; Cervino, Laura

    2015-04-01

    Deformable image registration (DIR) of fractional high-dose-rate (HDR) CT images is challenging due to the presence of applicators in the brachytherapy image. Point-to-point correspondence fails because of the undesired deformation vector fields (DVF) propagated from the applicator region (AR) to the surrounding tissues, which can potentially introduce significant DIR errors in dose mapping. This paper proposes a novel segmentation and point-matching enhanced efficient DIR (named SPEED) scheme to facilitate dose accumulation among HDR treatment fractions. In SPEED, a semi-automatic seed point generation approach is developed to obtain the incremented fore/background point sets to feed the random walks algorithm, which is used to segment and remove the AR, leaving empty AR cavities in the HDR CT images. A feature-based ‘thin-plate-spline robust point matching’ algorithm is then employed for AR cavity surface points matching. With the resulting mapping, a DVF defining on each voxel is estimated by B-spline approximation, which serves as the initial DVF for the subsequent Demons-based DIR between the AR-free HDR CT images. The calculated DVF via Demons combined with the initial one serve as the final DVF to map doses between HDR fractions. The segmentation and registration accuracy are quantitatively assessed by nine clinical HDR cases from three gynecological cancer patients. The quantitative analysis and visual inspection of the DIR results indicate that SPEED can suppress the impact of applicator on DIR, and accurately register HDR CT images as well as deform and add interfractional HDR doses.

  2. Energy and energy width measurement in the FNAL antiproton accumulator

    Energy Technology Data Exchange (ETDEWEB)

    Church, M.; Hsueh, S.; Rapidis, P.; Werkema, S.

    1991-10-01

    The Fermilab Antiproton Accumulator has recently been used to produce Charmonium resonances (charm quark, anti-charm quark bound states) in proton-antiproton annihilations using an internal H{sub 2} gas jet target. A measurement of the resonance mass and width may be obtained from a precise knowledge of the antiproton beam energy and energy spread. The beam energy is measured to an accuracy of 1 part in 10{sup 4} in the range 6.3 Gev to 4.1 Gev by measuring the orbit length and revolution frequency of the beam. The beam momentum spread is measured to an accuracy of 10% by measuring the beam frequency spread and the parameter {eta} = (P{sub beam}/F{sub rev}){center_dot}(dF{sub rev}/dP{sub beam}). These two measurement techniques are described in this report.

  3. Measurements of gamma-ray dose from a moderated 252Cf source

    International Nuclear Information System (INIS)

    McDonald, J.C.; Griffith, R.V.; Plato, P.; Miklos, J.

    1983-06-01

    The gamma-ray dose fraction from a moderated 252 Cf source was determined by using three types of dosimetry systems. Measurements were carried out in air at a distance of 35 cm from the surface of the moderating sphere (50 cm from the source which is at the center of the sphere) to the geometrical center of each detector. The moderating sphere is 0.8-mm-thick stainless steel shell filled with D 2 O and covered with 0.5 mm of cadmium. Measurements were also carried out with instruments and dosimeters positioned at the surface of a 40 cm x 40 cm x 15 cm plexiglass irradiation phantom whose front surface was also 35 cm from the surface of the moderating sphere. A-150 tissue-equivalent (TE) plastic ionization chambers and a TE proportional counter (TEPC) were used to measure tissue dose, from which the neutron dose equivalent was computed. The ratio of gamma-ray dose to the neutron dose equivalent was determined by using a relatively neutron-insensitive Geiger-Mueller (GM) counter and thermoluminescent dosimeters (TLD). In addition, the event-size spectrum measured by the TEPC was also used to compute the gamma-ray dose fraction. The average value for the ratio of gamma-ray dose to neutron dose equivalent was found to be 0.18 with an uncertainty of about +-18%

  4. Field measurement and interpretation of beta doses and dose rates

    International Nuclear Information System (INIS)

    Selby, J.M.; Swinth, K.L.; Hooker, C.D.; Kenoyer, J.L.

    1983-01-01

    A large number of portable survey instruments employing G.M., ionization chamber, and scintillation detectors used for gamma measurements are also used for monitoring in beta fields by using removable shields to separate the beta and gamma components of the radiation field. The difference does not correspond to an absorbed dose rate for the beta field due to a variety of factors. Among these factors are the dependence on beta energy, source-detector geometries, mixed fields and variable ambient conditions. Attempting to use such measurements directly can lead to errors as high as a factor of 100. Appropriate calibrations and correction factors can be used to reduce the errors in beta measurements to a tolerable level

  5. Feasibility study of entrance and exit dose measurements at the contra lateral breast with alanine/electron spin resonance dosimetry in volumetric modulated radiotherapy of breast cancer

    Science.gov (United States)

    Wagner, Daniela M.; Hüttenrauch, Petra; Anton, Mathias; von Voigts-Rhetz, Philip; Zink, Klemens; Wolff, Hendrik A.

    2017-07-01

    The Physikalisch-Technische Bundesanstalt has established a secondary standard measurement system for the dose to water, D W, based on alanine/ESR (Anton et al 2013 Phys. Med. Biol. 58 3259-82). The aim of this study was to test the established measurement system for the out-of-field measurements of inpatients with breast cancer. A set of five alanine pellets were affixed to the skin of each patient at the contra lateral breast beginning at the sternum and extending over the mammilla to the distal surface. During 28 fractions with 2.2 Gy per fraction, the accumulated dose was measured in four patients. A cone beam computer tomography (CBCT) scan was generated for setup purposes before every treatment. The reference CT dataset was registered rigidly and deformably to the CBCT dataset for 28 fractions. To take the actual alanine pellet position into account, the dose distribution was calculated for every fraction using the Acuros XB algorithm. The results of the ESR measurements were compared to the calculated doses. The maximum dose measured at the sternum was 19.9 Gy  ±  0.4 Gy, decreasing to 6.8 Gy  ±  0.2 Gy at the mammilla and 4.5 Gy  ±  0.1 Gy at the distal surface of the contra lateral breast. The absolute differences between the calculated and measured doses ranged from  -1.9 Gy to 0.9 Gy. No systematic error could be seen. It was possible to achieve a combined standard uncertainty of 1.63% for D W  =  5 Gy for the measured dose. The alanine/ESR method is feasible for in vivo measurements.

  6. Measuring the absorbed dose in critical organs during low rate dose brachytherapy with 137 Cs using thermoluminescent dosemeters

    International Nuclear Information System (INIS)

    Torres, A.; Gonzalez, P.R.; Furetta, C.; Azorin, J.; Andres, U.; Mendez, G.

    2003-01-01

    Intracavitary Brachytherapy is one of the most used methods for the treatment of the cervical-uterine cancer. This treatment consists in the insertion of low rate dose 137 Cs sources into the patient. The most used system for the treatment dose planning is that of Manchester. This planning is based on sources, which are considered fixed during the treatment. However, the experience has shown that, during the treatment, the sources could be displaced from its initial position, changing the dose from that previously prescribed. For this reason, it is necessary to make measurements of the absorbed dose to the surrounding organs (mainly bladder and rectum). This paper presents the results of measuring the absorbed dose using home-made LiF: Mg, Cu, P + Ptfe thermoluminescent dosimeters (TLD). Measurements were carried out in-vivo during 20 minutes at the beginning and at the end of the treatments. Results showed that the absorbed dose to the critical organs vary significantly due to the movement of the patient during the treatment. (Author)

  7. Measuring Social Capital Accumulation in Rural Development

    DEFF Research Database (Denmark)

    Teilmann, Kasper

    2012-01-01

    Using a theoretical framework, the study proposes an index that can measure the social capital of local action group (LAG) projects. The index is founded on four indicators: number of ties, bridging social capital, recognition, and diversity, which are aggregated into one social capital index....... The index has been tested in LAG-Djursland, Denmark, and the study further investigates whether the organisational affiliation, project financing, and LAG co-financing can explain the degree of social capital accumulation. Furthermore, the author has tested if there are connections between motivation...... for pursuing development projects similar to those implemented previously and the degree of social capital. The paper concludes that there are indications that projects hosted by municipalities tend to show the most social capital, there is no connection between the amount of project financing and social...

  8. Advances in absorbed dose measurement standards at the australian radiation laboratory

    International Nuclear Information System (INIS)

    Boas, J.F.; Hargrave, N.J.; Huntley, R.B.; Kotler, L.H.; Webb, D.V.; Wise, K.N.

    1996-01-01

    The applications of ionising radiation in the medical and industrial fields require both an accurate knowledge of the amount of ionising radiation absorbed by the medium in question and the capability of relating this to National and International standards. The most useful measure of the amount of radiation is the absorbed dose which is defined as the energy absorbed per unit mass. For radiotherapy, the reference medium is water, even though the measurement of the absorbed dose to water is not straightforward. Two methods are commonly used to provide calibrations in absorbed dose to water. The first is the calibration of the chamber in terms of exposure in a Cobalt-60 beam, followed by the conversion by a protocol into dose to water in this and higher energy beams. The other route is via the use of a graphite calorimeter as a primary standard device, where the conversion from absorbed dose to graphite to absorbed dose in water is performed either by theoretical means making use of cavity ionisation theory, or by experiment where the graphite calorimeter and secondary standard ionisation chamber are placed at scaled distances from the source of the radiation beam (known as the Dose-Ratio method). Extensive measurements have been made at Cobalt-60 at ARL using both the exposure and absorbed dose to graphite routes. Agreement between the ARL measurements and those based on standards maintained by ANSTO and NPL is within ± 0.3%. Absorbed dose measurements have also been performed at ARL with photon beams of nominal energy 16 and 19 MeV obtained from the ARL linac. The validity of the protocols at high photon energies, the validity of the methods used to convert from absorbed dose in graphite to absorbed dose in water and the validity of the indices used to specify the beams are discussed. Brief mention will also be made of the establishment of a calibration facility for neutron monitors at ARL and of progress in the development of ERP dosimetry

  9. Advances in absorbed dose measurement standards at the australian radiation laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Boas, J.F.; Hargrave, N.J.; Huntley, R.B.; Kotler, L.H.; Webb, D.V.; Wise, K.N. [Australian Radiation Laboratory, Yallambie, VIC (Australia)

    1996-12-31

    The applications of ionising radiation in the medical and industrial fields require both an accurate knowledge of the amount of ionising radiation absorbed by the medium in question and the capability of relating this to National and International standards. The most useful measure of the amount of radiation is the absorbed dose which is defined as the energy absorbed per unit mass. For radiotherapy, the reference medium is water, even though the measurement of the absorbed dose to water is not straightforward. Two methods are commonly used to provide calibrations in absorbed dose to water. The first is the calibration of the chamber in terms of exposure in a Cobalt-60 beam, followed by the conversion by a protocol into dose to water in this and higher energy beams. The other route is via the use of a graphite calorimeter as a primary standard device, where the conversion from absorbed dose to graphite to absorbed dose in water is performed either by theoretical means making use of cavity ionisation theory, or by experiment where the graphite calorimeter and secondary standard ionisation chamber are placed at scaled distances from the source of the radiation beam (known as the Dose-Ratio method). Extensive measurements have been made at Cobalt-60 at ARL using both the exposure and absorbed dose to graphite routes. Agreement between the ARL measurements and those based on standards maintained by ANSTO and NPL is within {+-} 0.3%. Absorbed dose measurements have also been performed at ARL with photon beams of nominal energy 16 and 19 MeV obtained from the ARL linac. The validity of the protocols at high photon energies, the validity of the methods used to convert from absorbed dose in graphite to absorbed dose in water and the validity of the indices used to specify the beams are discussed. Brief mention will also be made of the establishment of a calibration facility for neutron monitors at ARL and of progress in the development of ERP dosimetry.

  10. Unit of measurement used and parent medication dosing errors.

    Science.gov (United States)

    Yin, H Shonna; Dreyer, Benard P; Ugboaja, Donna C; Sanchez, Dayana C; Paul, Ian M; Moreira, Hannah A; Rodriguez, Luis; Mendelsohn, Alan L

    2014-08-01

    Adopting the milliliter as the preferred unit of measurement has been suggested as a strategy to improve the clarity of medication instructions; teaspoon and tablespoon units may inadvertently endorse nonstandard kitchen spoon use. We examined the association between unit used and parent medication errors and whether nonstandard instruments mediate this relationship. Cross-sectional analysis of baseline data from a larger study of provider communication and medication errors. English- or Spanish-speaking parents (n = 287) whose children were prescribed liquid medications in 2 emergency departments were enrolled. Medication error defined as: error in knowledge of prescribed dose, error in observed dose measurement (compared to intended or prescribed dose); >20% deviation threshold for error. Multiple logistic regression performed adjusting for parent age, language, country, race/ethnicity, socioeconomic status, education, health literacy (Short Test of Functional Health Literacy in Adults); child age, chronic disease; site. Medication errors were common: 39.4% of parents made an error in measurement of the intended dose, 41.1% made an error in the prescribed dose. Furthermore, 16.7% used a nonstandard instrument. Compared with parents who used milliliter-only, parents who used teaspoon or tablespoon units had twice the odds of making an error with the intended (42.5% vs 27.6%, P = .02; adjusted odds ratio=2.3; 95% confidence interval, 1.2-4.4) and prescribed (45.1% vs 31.4%, P = .04; adjusted odds ratio=1.9; 95% confidence interval, 1.03-3.5) dose; associations greater for parents with low health literacy and non-English speakers. Nonstandard instrument use partially mediated teaspoon and tablespoon-associated measurement errors. Findings support a milliliter-only standard to reduce medication errors. Copyright © 2014 by the American Academy of Pediatrics.

  11. Human Action Recognition Using Ordinal Measure of Accumulated Motion

    Directory of Open Access Journals (Sweden)

    Kim Wonjun

    2010-01-01

    Full Text Available This paper presents a method for recognizing human actions from a single query action video. We propose an action recognition scheme based on the ordinal measure of accumulated motion, which is robust to variations of appearances. To this end, we first define the accumulated motion image (AMI using image differences. Then the AMI of the query action video is resized to a subimage by intensity averaging and a rank matrix is generated by ordering the sample values in the sub-image. By computing the distances from the rank matrix of the query action video to the rank matrices of all local windows in the target video, local windows close to the query action are detected as candidates. To find the best match among the candidates, their energy histograms, which are obtained by projecting AMI values in horizontal and vertical directions, respectively, are compared with those of the query action video. The proposed method does not require any preprocessing task such as learning and segmentation. To justify the efficiency and robustness of our approach, the experiments are conducted on various datasets.

  12. Estimation of Electron Dose Delivered by a 0.4 MeV Accelerator from Bremsstrahlung Dose Measurements

    DEFF Research Database (Denmark)

    Karadjov, A. G.; Hansen, Jørgen-Walther

    1980-01-01

    Determination of a 0.4 MeV electron dose from a bremsstrahlung dose measurement using a converter-detector system is considered. The detector used is a Frickle dosimeter, and the converters are aluminum, copper and lead foils. Optimal converter thickness is ascertained experimentally for each mat...... materials within a Z-range of 13–82. A linear relation is found between bremsstrahlung dose and electron dose ranging from 2 to 20 Mrad. Finally the effect of converter area on detector response is studied....

  13. Measuring dose from radiotherapy treatments in the vicinity of a cardiac pacemaker.

    Science.gov (United States)

    Peet, Samuel C; Wilks, Rachael; Kairn, Tanya; Crowe, Scott B

    2016-12-01

    This study investigated the dose absorbed by tissues surrounding artificial cardiac pacemakers during external beam radiotherapy procedures. The usefulness of out-of-field reference data, treatment planning systems, and skin dose measurements to estimate the dose in the vicinity of a pacemaker was also examined. Measurements were performed by installing a pacemaker onto an anthropomorphic phantom, and using radiochromic film and optically stimulated luminescence dosimeters to measure the dose in the vicinity of the device during the delivery of square fields and clinical treatment plans. It was found that the dose delivered in the vicinity of the cardiac device was unevenly distributed both laterally and anteroposteriorly. As the device was moved distally from the square field, the dose dropped exponentially, in line with out-of-field reference data in the literature. Treatment planning systems were found to substantially underestimate the dose for volumetric modulated arc therapy, helical tomotherapy, and 3D conformal treatments. The skin dose was observed to be either greater or lesser than the dose received at the depth of the device, depending on the treatment site, and so care should be if skin dose measurements are to be used to estimate the dose to a pacemaker. Square field reference data may be used as an upper estimate of absorbed dose per monitor unit in the vicinity of a cardiac device for complex treatments involving multiple gantry angles. Copyright © 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  14. Study of radioactive sources accumulation with application of thermoluminescence dosemeters on the base of alkaline earth metals sulfates

    International Nuclear Information System (INIS)

    Tokbergenov, I.; Sadykov, T.

    2001-01-01

    Methodic for study of accumulation and distribution of radioactive sources in a nature objects is developed. An essence of the method consists of in that quantity of accumulated radioactive sources in a nature objects is defining by absorption dose measured with help of thermoluminescent dosemeters on the base of alkaline earth metals sulfates such as CaSO 4 :Dy and SrSO 4 :Eu

  15. Measurements of dose with individual FAMOS transistors

    Energy Technology Data Exchange (ETDEWEB)

    Scheick, L.Z.; McNulty, P.J.; Roth, D.R.; Davis, M.G.; Mason, B.E.

    1999-12-01

    A new method is described for measuring the doses absorbed by microstructures from an exposure to ionizing radiation. The decrease in the duration of UltraViolet light (UV) exposure required to erase each cell of a commercial UltraViolet erasable Programmable Read Only Memory (UVPROM) correlates with the dose absorbed by the floating gate of that transistor. This technique facilitates analysis of the microdose distribution across the array and the occurrence of Single Event Upset (SEU) like anomalous shifts due to rare large energy-deposition events.

  16. Measurements of dose with individual FAMOS transistors

    International Nuclear Information System (INIS)

    Scheick, L.Z.; McNulty, P.J.; Roth, D.R.; Davis, M.G.; Mason, B.E.

    1999-01-01

    A new method is described for measuring the doses absorbed by microstructures from an exposure to ionizing radiation. The decrease in the duration of UltraViolet light (UV) exposure required to erase each cell of a commercial UltraViolet erasable Programmable Read Only Memory (UVPROM) correlates with the dose absorbed by the floating gate of that transistor. This technique facilitates analysis of the microdose distribution across the array and the occurrence of Single Event Upset (SEU) like anomalous shifts due to rare large energy-deposition events

  17. Trend of collective dose and dose reduction measures of Mitsubishi Electric Corporation workers in nuclear power plants

    International Nuclear Information System (INIS)

    Yamato, I.; Nakayama, T.; Shimokawa, F.; Yamamoto, T.

    1996-01-01

    MELCO has supplied the reactor instrumentation control system, reactor coolant pump motors, turbine generator and central control system for the pressurized water type nuclear power plant. For the legal periodical inspection and repair work, MELCO has also received orders for the periodical inspection for 23 power plants (including 4 plants under construction) of 5 electric power companies, and executed the inspection work from the view point of preventive maintenance. The annual dose for MELCO's workers is liable to be decreased in spite of increased number of plants. The dose for new plant in particular is 50, or less as compared with that for conventional plant. This is because the measures taken for the conventional plant against the dose reduction is reflected upon the new plant. The dose reduction measures are taken for each system for which order was received. Such measures are mainly intended to improve the work procedures and equipment for reduction of work time in the radioactive area and to arrange the working process, so as to perform the work in such period when the dose level at the working environment is low. To enhance the workers' consciousness for reduction of dose, MELCO provided the workers with dose predictive training, and let them aware of such items known at the tool box briefing (TBX), which could realize the dose reduction for workers. MELCO has been positively promoting the activity to arrange the desirable work environment for extermination of 3Ks (giken, gitsui, titanai) or 3Ds (dangerous, difficult, dirty) including protection against radiation in corporation with electric power companies. (author)

  18. Dose measurement, its distribution and individual external dose assessments of inhabitants in the high background radiation areas in China

    International Nuclear Information System (INIS)

    Morishima, Hiroshige; Koga, Taeko; Tatsumi, Kusuo; Nakai, Sayaka; Sugahara, Tsutomu; Yuan Yongling; Wei Luxin

    2000-01-01

    As a part of the China-Japan cooperative research on natural radiation epidemiology, we have carried out a dose-assessment study to evaluate the external exposure to natural radiation in the high background radiation areas (HBRA) of Yangjiang in Guangdong province and in the control areas (CA) of Enping prefecture since 1991. Because of the difficulties in measuring the individual doses of all inhabitants directly by personal dosimeters, an indirect method was applied in which the exposed individual doses were estimated from the environmental radiation doses measured by survey meters and the occupancy factors of each hamlet. We analyzed the dose in the hamlets and the variation in the occupancy factors to obtain the parameters of dose estimation on the inhabitants in selected hamlets; Madi and several hamlets of different dose levels in HBRA and Hampizai hamlet in CA. With these parameters, we estimated individual dose rates and compared them with those obtained from direct measurement using dosimeters carried by selected individuals. The results obtained are as follows. The environmental radiation doses are influenced by the natural radioactive nuclide concentrations in building materials, the age of the building and the arrangement of the houses in a hamlet. There existed a fairly large and heterogeneous distribution of indoor and outdoor environmental radiations. The indoor radiation doses were due to exposure from the natural radioactive nuclides in the building materials and were about two times as large as the outdoor radiation doses. The difference between indoor and outdoor doses was not observed in CA. The occupancy factor was influenced by the age of individuals and by the season of the year. The occupancy factor was higher for infants and aged individuals than for other age groups. This lead to higher dose rates of exposure to those age groups. A good correlation was observed between the dose assessed indirectly and that measured directly and the

  19. Dose measurement, its distribution and individual external dose assessments of inhabitants in the high background radiation areas in China

    Energy Technology Data Exchange (ETDEWEB)

    Morishima, Hiroshige; Koga, Taeko [Kinki Univ., Higashi-Osaka, Osaka (Japan). Atomic Energy Research Inst.; Tatsumi, Kusuo; Nakai, Sayaka; Sugahara, Tsutomu; Yuan Yongling; Wei Luxin

    2000-10-01

    As a part of the China-Japan cooperative research on natural radiation epidemiology, we have carried out a dose-assessment study to evaluate the external exposure to natural radiation in the high background radiation areas (HBRA) of Yangjiang in Guangdong province and in the control areas (CA) of Enping prefecture since 1991. Because of the difficulties in measuring the individual doses of all inhabitants directly by personal dosimeters, an indirect method was applied in which the exposed individual doses were estimated from the environmental radiation doses measured by survey meters and the occupancy factors of each hamlet. We analyzed the dose in the hamlets and the variation in the occupancy factors to obtain the parameters of dose estimation on the inhabitants in selected hamlets; Madi and several hamlets of different dose levels in HBRA and Hampizai hamlet in CA. With these parameters, we estimated individual dose rates and compared them with those obtained from direct measurement using dosimeters carried by selected individuals. The results obtained are as follows. The environmental radiation doses are influenced by the natural radioactive nuclide concentrations in building materials, the age of the building and the arrangement of the houses in a hamlet. There existed a fairly large and heterogeneous distribution of indoor and outdoor environmental radiations. The indoor radiation doses were due to exposure from the natural radioactive nuclides in the building materials and were about two times as large as the outdoor radiation doses. The difference between indoor and outdoor doses was not observed in CA. The occupancy factor was influenced by the age of individuals and by the season of the year. The occupancy factor was higher for infants and aged individuals than for other age groups. This lead to higher dose rates of exposure to those age groups. A good correlation was observed between the dose assessed indirectly and that measured directly and the

  20. Measurement of radiation dose with a PC-based instrument

    International Nuclear Information System (INIS)

    Jangland, L.; Neubeck, R.

    1994-01-01

    The purpose of this study was to investigate in what way the introduction of Digital Subtraction Angiography has influenced absorbed doses to the patient and personnel. Calculation of the energy imparted to the patient, ε, was based on measurements of the dose-area product, tube potential and tube current which were registered with a PC-based instrument. The absorbed doses to the personnel were measured with TLD. The measurements on the personnel were made only at the digital system. The results indicate large variations in ε between different types of angiographic examinations of the same type. The total ε were similar on both systems, although the relative contribution from image acquisition and fluoroscopy were different. At the conventional system fluoroscopy and image acquisition contributed almost equally to the total ε. At the digital system 25% of the total ε was due to fluoroscopy and 75% to image acquisition. The differences were due to longer fluoroscopic times on the conventional system, mainly due to lack of image memory and road mapping, and lower ε/image, due to lower dose settings to the film changer compared to the image intensifier on the digital system. 11 refs., 8 figs., 9 tabs

  1. Examination of observed and predicted measures of creep cavitation damage accumulation

    Energy Technology Data Exchange (ETDEWEB)

    Brear, J M; Church, J M [ERA Technology Ltd., Leatherhead (United Kingdom); Eggeler, G [University of Bochum-Ruhr (Germany)

    1999-12-31

    Brittle intergranular cavitation represents a primary degradation mechanism for high temperature plant operating within the creep range. Fundamental to formulating estimates of remanent life, or consumed life fraction for such components are: the observation and quantification of the level of actual creep cavitation, typically using an A-parameter type approach, and the correlation of observed creep damage accumulation with some phenomenological model which characterizes the rate of damage evolution and, thereby, rupture lifetime. The work described here treats inhomogeneous damage accumulation - in otherwise uniform material and loading situations. Extensions to the A-parameter are considered as a practical measure of damage localization and an extension of the Kachanov-Rabotnov continuum damage mechanics model is proposed to allow theoretical treatment. (orig.) 4 refs.

  2. Examination of observed and predicted measures of creep cavitation damage accumulation

    Energy Technology Data Exchange (ETDEWEB)

    Brear, J.M.; Church, J.M. [ERA Technology Ltd., Leatherhead (United Kingdom); Eggeler, G. [University of Bochum-Ruhr (Germany)

    1998-12-31

    Brittle intergranular cavitation represents a primary degradation mechanism for high temperature plant operating within the creep range. Fundamental to formulating estimates of remanent life, or consumed life fraction for such components are: the observation and quantification of the level of actual creep cavitation, typically using an A-parameter type approach, and the correlation of observed creep damage accumulation with some phenomenological model which characterizes the rate of damage evolution and, thereby, rupture lifetime. The work described here treats inhomogeneous damage accumulation - in otherwise uniform material and loading situations. Extensions to the A-parameter are considered as a practical measure of damage localization and an extension of the Kachanov-Rabotnov continuum damage mechanics model is proposed to allow theoretical treatment. (orig.) 4 refs.

  3. The antiproton depth–dose curve measured with alanine detectors

    CERN Document Server

    Bassler, Niels; Palmans, Hugo; Holzscheiter, Michael H; Kovacevic, Sandra

    2008-01-01

    n this paper we report on the measurement of the antiproton depth–dose curve, with alanine detectors. The results are compared with simulations using the particle energy spectrum calculated by FLUKA, and using the track structure model of Hansen and Olsen for conversion of calculated dose into response. A good agreement is observed between the measured and calculated relative effectiveness although an underestimation of the measured values beyond the Bragg-peak remains unexplained. The model prediction of response of alanine towards heavy charged particles encourages future use of the alanine detectors for dosimetry of mixed radiation fields.

  4. Breast internal dose measurements in a physical thoracic phantom

    Energy Technology Data Exchange (ETDEWEB)

    Silva, S.D.; Oliveira, M.A.; Castro, A.L.S.; Dias, H.G.; Nogueira, L.B.; Campos, T.P.R., E-mail: sadonatosilva@hotmail.com [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Departamento de Engenharia Nuclear; Hospital das Clinicas de Uberlandia, MG (Brazil). Departamento de Oncologia; Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Anatomia e Departamento de Imagem

    2017-10-01

    Radiotherapy is a cancer treatment intended to deposit the entire prescribed dose homogeneously into a target volume in order to eliminate the tumor and to spare the surrounding healthy tissues. This paper aimed to provide a dosimetric comparison between the treatment planning system (TPS) ECLIPSE from Varian Medical Systems and the internal dosimetric measurements in a breast phantom. The methodology consisted in performing a 3D conformal radiotherapy planning with two tangential opposite parallel fields applied to the synthetic breast in a thoracic phantom. The irradiation was reproduced in the Varian Linear accelerator, model SL - 20 Precise, 6 MV energy. EBT2 Radiochromic films, placed into the glandular equivalent tissue of the breast, were used to measure the spatial dose distribution. The absorbed dose was compared to those values predicted by the treatment planning system; besides, the dosimetric uncertainties were analyzed. The modal absorbed dose was in agreement with the prescribed value of 180 cGy, although few high dose points between 180 and 220 cGy were detected. The findings suggested a non-uniform dose distribution in the glandular tissue of the synthetic breast, similar to those found in the TPS, associated with the irregular anatomic breast shape and presence of inhomogeneities next to the thoracic wall generated by the low lung density. (author)

  5. Peripheral dose measurement for CyberKnife radiosurgery with upgraded linac shielding

    International Nuclear Information System (INIS)

    Chuang, Cynthia F.; Larson, David A.; Zytkovicz, Andrea; Smith, Vernon; Petti, Paula L.

    2008-01-01

    The authors investigated the peripheral dose reduction for CyberKnife radiosurgery treatments after the installation of a linac shielding upgrade. As in a previous investigation, the authors considered two treatment plans, one for a hypothetical target in the brain and another for a target in the thorax, delivered to an anthropomorphic phantom. The results of the prior investigation showed that the CyberKnife delivered significantly higher peripheral doses than comparable model C Gamma Knife or IMRT treatments. Current measurements, after the linac shielding upgrade, demonstrate that the additional shielding decreased the peripheral dose, expressed as a percentage of the delivered monitor units (MU), by a maximum of 59%. The dose reduction was greatest for cranial-caudal distances from the field edge less than 30 cm, and at these distances, the CyberKnife peripheral dose, expressed as a percentage of the delivered MU, is now comparable to that measured for the other treatment modalities in our previous investigation. For distances between 30 and 70 cm from the field edge, the additional shielding reduced the peripheral dose by between 20% and 55%. At these distances, the CyberKnife peripheral dose remains higher than doses measured in our previous study for the model C Gamma Knife and IMRT

  6. Ambient dose measurement in some CT departments in Khartoum State

    International Nuclear Information System (INIS)

    Mohammed, S. A. H.

    2012-09-01

    Computerized Tomography (CT) is now one of the most important radiological examinations world wide.The frequency of CT examinations is increasing rapidly from 2% of all radiological examinations in some countries a decade age to 10-15% now. During the imaging procedure, staff may expose to a significant dose. Therefore, ambient dose measurement is important in the shortage of regular personal monitoring in sudan. This study intended to evaluate the ambient dose at some CT departments (Medical Military hospital, Alamal National Hospital, Elnelin Diagnostic Center and Modern Medical Centre). These departments were equipped with daul, 16 and 64 multi detector CT machines. A survey meter (Radios) was used to measure ambient doses in three locations: Doors, Control Rooms and Adjacent Rooms. The ambient dose equivalent (scatter dose) was measured at various distances from the isocenter of the CT unit at various angles to establish isodose cartography. The mean and range of radiation at control room is 10.00-0.20 and mean (7.05μSv/hr,) reception 1.0-0 (0.40) and doors 4.00-100.00 (73.5) for height 1 meter above the ground. For height 2 meters at control room 0-10.00 (6,75), reception 0-90.00 (30) at door 9.00-90.00 (49.50). This study confirms that low levels of radiation dose are received by staff during CT imaging and these levels are within safe limits as prescribed by the national and international regulations. (Author)

  7. Characterisation of a MOSFET-based detector for dose measurement under megavoltage electron beam radiotherapy

    Science.gov (United States)

    Jong, W. L.; Ung, N. M.; Tiong, A. H. L.; Rosenfeld, A. B.; Wong, J. H. D.

    2018-03-01

    The aim of this study is to investigate the fundamental dosimetric characteristics of the MOSkin detector for megavoltage electron beam dosimetry. The reproducibility, linearity, energy dependence, dose rate dependence, depth dose measurement, output factor measurement, and surface dose measurement under megavoltage electron beam were tested. The MOSkin detector showed excellent reproducibility (>98%) and linearity (R2= 1.00) up to 2000 cGy for 4-20 MeV electron beams. The MOSkin detector also showed minimal dose rate dependence (within ±3%) and energy dependence (within ±2%) over the clinical range of electron beams, except for an energy dependence at 4 MeV electron beam. An energy dependence correction factor of 1.075 is needed when the MOSkin detector is used for 4 MeV electron beam. The output factors measured by the MOSkin detector were within ±2% compared to those measured with the EBT3 film and CC13 chamber. The measured depth doses using the MOSkin detector agreed with those measured using the CC13 chamber, except at the build-up region due to the dose volume averaging effect of the CC13 chamber. For surface dose measurements, MOSkin measurements were in agreement within ±3% to those measured using EBT3 film. Measurements using the MOSkin detector were also compared to electron dose calculation algorithms namely the GGPB and eMC algorithms. Both algorithms were in agreement with measurements to within ±2% and ±4% for output factor (except for the 4 × 4 cm2 field size) and surface dose, respectively. With the uncertainties taken into account, the MOSkin detector was found to be a suitable detector for dose measurement under megavoltage electron beam. This has been demonstrated in the in vivo skin dose measurement on patients during electron boost to the breast tumour bed.

  8. Adaptive plan selection vs. re-optimisation in radiotherapy for bladder cancer: A dose accumulation comparison

    International Nuclear Information System (INIS)

    Vestergaard, Anne; Muren, Ludvig Paul; Søndergaard, Jimmi; Elstrøm, Ulrik Vindelev; Høyer, Morten; Petersen, Jørgen B.

    2013-01-01

    Purpose: Patients with urinary bladder cancer are obvious candidates for adaptive radiotherapy (ART) due to large inter-fractional variation in bladder volumes. In this study we have compared the normal tissue sparing potential of two ART strategies: daily plan selection (PlanSelect) and daily plan re-optimisation (ReOpt). Materials and methods: Seven patients with bladder cancer were included in the study. For the PlanSelect strategy, a patient-specific library of three plans was generated, and the most suitable plan based on the pre-treatment cone beam CT (CBCT) was selected. For the daily ReOpt strategy, plans were re-optimised based on the CBCT from each daily fraction. Bladder contours were propagated to the CBCT scan using deformable image registration (DIR). Accumulated dose distributions for the ART strategies as well as the non-adaptive RT were calculated. Results: A considerable sparing of normal tissue was achieved with both ART approaches, with ReOpt being the superior technique. Compared to non-adaptive RT, the volume receiving more than 57 Gy (corresponding to 95% of the prescribed dose) was reduced to 66% (range 48–100%) for PlanSelect and to 41% (range 33–50%) for ReOpt. Conclusion: This study demonstrated a considerable normal tissue sparing potential of ART for bladder irradiation, with clearly superior results by daily adaptive re-optimisation

  9. Precedents For Authorization Of Contents Using Dose Rate Measurements

    International Nuclear Information System (INIS)

    Abramczyk, G.; Bellamy, S.; Nathan, S.; Loftin, B.

    2012-01-01

    For the transportation of Radioactive Material (RAM) packages, the requirements for the maximum allowed dose rate at the package surface and in its vicinity are given in Title 10 of the Code of Federal Regulations, Section 71.47. The regulations are based on the acceptable dose rates to which the public, workers, and the environment may be exposed. As such, the regulations specify dose rates, rather than quantity of radioactive isotopes and require monitoring to confirm the requirements are met. 10CFR71.47 requires that each package of radioactive materials offered for transportation must be designed and prepared for shipment so that under conditions normally incident to transportation the radiation level does not exceed 2 mSv/h (200 mrem/h) at any point on the external Surface of the package, and the transport index does not exceed 10. Before shipment, the dose rate of the package is determined by measurement, ensuring that it conforms to the regulatory limits, regardless of any analyses. This is the requirement for all certified packagings. This paper discusses the requirements for establishing the dose rates when shipping RAM packages and the precedents for meeting these requirements by measurement.

  10. Dose-area product measurement for patients in diagnostic radiography

    International Nuclear Information System (INIS)

    Alkhawad, Safaa Ibrahim Awad Elkarim

    2001-09-01

    There is a wide spread of the utilization of medical diagnostic x-ray in Sudan upon the last years, in private clinics as well as in public hospitals. The aim of this study was to measure the doses to patients from x-ray in radiography departments in Khartoum State. Use was made of ionization chamber that measures the product of dose times the exposed area of the patient in units of Gy cm 2 . The work was performed in 7 hospitals over 250 patients. 71.2% of the patients were males and 28.8% females. From this work, it appears that the chest radiography represent 42% of the total exposure of human body organs to radiography, there was also a clear variation in doses resulting from this exposure for different x-ray machines. The results of this study were compared with similar from Germany, Finland, New Zealand and Norway; which are recently available studies. The comparison showed those investigation of abdomen, spine and pelvis result in higher radiation doses. No data for limb exposure were obtained from these countries, in Sudan exposure of the limb carry radiation doses compared to the rest of the human body.(Author)

  11. The use of deciduous molars in EPR dose reconstruction

    International Nuclear Information System (INIS)

    El-faramawy, N.A.; Wieser, A.

    2005-01-01

    The use of deciduous teeth in EPR dose reconstruction has the unique potential to measure individual doses that were accumulated in the early childhood in the age up to 12 years. It was found previously that due to the small size of deciduous incisors, the available amount of enamel is not sufficient for EPR measurements. Therefore, dose assessment with deciduous incisors can only be done by measurement of whole teeth, including enamel and dentine. The measurement of whole teeth instead of enamel alone is possibly less reliable for dose reconstruction because the stability of CO 2 - radicals (that are an indicator for the absorbed dose) in biologically active dentine is not known. In the present study naturally loosed deciduous molars were investigated. The feasibility of separating enamel from small size molars was analysed. EPR spectrum parameters of whole molars and separated enamel only were evaluated before and after laboratory irradiation. The EPR signal amplitudes of the CO 2 - and native signals were determined by spectrum deconvolution, in dependence on radiation dose in the range 0.1 - 10 Gy. The fading at room temperature of native and CO 2 - EPR signals was analysed. The detection threshold for absorbed dose in enamel was determined.

  12. Measurement of spatial dose-rate distribution using a position sensitive detector

    International Nuclear Information System (INIS)

    Emoto, T.; Torii, T.; Nozaki, T.; Ando, H.

    1994-01-01

    Recently, the radiation detectors using plastic scintillation fibers (PSF) have been developed to measure the positions exposed to radiation such as neutrons and high energy charged particles. In particular, the time of flight (TOF) method for measuring the difference of time that two directional signals of scintillation light reach both ends of a PSF is a rather simple method for the measurement of the spatial distribution of fast neutron fluence rate. It is possible to use the PSF in nuclear facility working areas because of its flexibility, small diameter and long length. In order to apply TOF method to measure spatial gamma dose rate distribution, the characteristic tests of a detector using PSFs were carried out. First, the resolution of irradiated positions and the counting efficiency were measured with collimated gamma ray. The sensitivity to unit dose rate was also obtained. The measurement of spatial dose rate distribution was also carried out. The sensor is made of ten bundled PSFs, and the experimental setup is described. The experiment and the results are reported. It was found that the PSF detector has the good performance to measure spatial gamma dose rate distribution. (K.I.)

  13. Dose reconstruction in deforming lung anatomy: Dose grid size effects and clinical implications

    International Nuclear Information System (INIS)

    Rosu, Mihaela; Chetty, Indrin J.; Balter, James M.; Kessler, Marc L.; McShan, Daniel L.; Ten Haken, Randall K.

    2005-01-01

    In this study we investigated the accumulation of dose to a deforming anatomy (such as lung) based on voxel tracking and by using time weighting factors derived from a breathing probability distribution function (p.d.f.). A mutual information registration scheme (using thin-plate spline warping) provided a transformation that allows the tracking of points between exhale and inhale treatment planning datasets (and/or intermediate state scans). The dose distributions were computed at the same resolution on each dataset using the Dose Planning Method (DPM) Monte Carlo code. Two accumulation/interpolation approaches were assessed. The first maps exhale dose grid points onto the inhale scan, estimates the doses at the 'tracked' locations by trilinear interpolation and scores the accumulated doses (via the p.d.f.) on the original exhale data set. In the second approach, the 'volume' associated with each exhale dose grid point (exhale dose voxel) is first subdivided into octants, the center of each octant is mapped to locations on the inhale dose grid and doses are estimated by trilinear interpolation. The octant doses are then averaged to form the inhale voxel dose and scored at the original exhale dose grid point location. Differences between the interpolation schemes are voxel size and tissue density dependent, but in general appear primarily only in regions with steep dose gradients (e.g., penumbra). Their magnitude (small regions of few percent differences) is less than the alterations in dose due to positional and shape changes from breathing in the first place. Thus, for sufficiently small dose grid point spacing, and relative to organ motion and deformation, differences due solely to the interpolation are unlikely to result in clinically significant differences to volume-based evaluation metrics such as mean lung dose (MLD) and tumor equivalent uniform dose (gEUD). The overall effects of deformation vary among patients. They depend on the tumor location, field

  14. Direct measurement of annual β dose using TLD on porcelain

    International Nuclear Information System (INIS)

    Leung, P.L.; Stokes, M.J.; Xia Junding; Wang Weida; Zhou Zhixin

    1999-01-01

    In order to improve accuracy of TL authentication test for porcelain, a method of direct measurement of annual β dose using ultrathin TLD (CaSO 4 :Tm) on porcelain was studied. Since the TLD was placed into a hole left after sampling for the TL measurement, the method will not cause any new damage to the studied object. The results show that the technique is suitable for measuring annual β dose and improving accuracy of TL authentication test for both porcelain and pottery

  15. Real-time measurement and monitoring of absorbed dose for electron beams

    Science.gov (United States)

    Korenev, Sergey; Korenev, Ivan; Rumega, Stanislav; Grossman, Leon

    2004-09-01

    The real-time method and system for measurement and monitoring of absorbed dose for industrial and research electron accelerators is considered in the report. The system was created on the basis of beam parameters method. The main concept of this method consists in the measurement of dissipated kinetic energy of electrons in the irradiated product, determination of number of electrons and mass of irradiated product in the same cell by following calculation of absorbed dose in the cell. The manual and automation systems for dose measurements are described. The systems are acceptable for all types of electron accelerators.

  16. Real-time measurement and monitoring of absorbed dose for electron beams

    Energy Technology Data Exchange (ETDEWEB)

    Korenev, Sergey E-mail: sergey_korenev@steris.com; Korenev, Ivan; Rumega, Stanislav; Grossman, Leon

    2004-10-01

    The real-time method and system for measurement and monitoring of absorbed dose for industrial and research electron accelerators is considered in the report. The system was created on the basis of beam parameters method. The main concept of this method consists in the measurement of dissipated kinetic energy of electrons in the irradiated product, determination of number of electrons and mass of irradiated product in the same cell by following calculation of absorbed dose in the cell. The manual and automation systems for dose measurements are described. The systems are acceptable for all types of electron accelerators.

  17. Real-time measurement and monitoring of absorbed dose for electron beams

    International Nuclear Information System (INIS)

    Korenev, Sergey; Korenev, Ivan; Rumega, Stanislav; Grossman, Leon

    2004-01-01

    The real-time method and system for measurement and monitoring of absorbed dose for industrial and research electron accelerators is considered in the report. The system was created on the basis of beam parameters method. The main concept of this method consists in the measurement of dissipated kinetic energy of electrons in the irradiated product, determination of number of electrons and mass of irradiated product in the same cell by following calculation of absorbed dose in the cell. The manual and automation systems for dose measurements are described. The systems are acceptable for all types of electron accelerators

  18. Fiber optical dose rate measurement based on the luminescence of beryllium oxide

    Directory of Open Access Journals (Sweden)

    Teichmann Tobias

    2018-01-01

    Full Text Available This work presents a fiber optical dose rate measurement system based on the radioluminescence and optically stimulated luminescence of beryllium oxide. The system consists of a small, radiation sensitive probe which is coupled to a light detection unit with a long and flexible light guide. Exposing the beryllium oxide probe to ionizing radiation results in the emission of light with an intensity which is proportional to the dose rate. Additionally, optically stimulated luminescence can be used to obtain dose and dose rate information during irradiation or retrospectively. The system is capable of real time dose rate measurements in fields of high dose rates and dose rate gradients and in complex, narrow geometries. This enables the application for radiation protection measurements as well as for quality control in radiotherapy. One inherent drawback of fiber optical dosimetry systems is the generation of Cherenkov radiation and luminescence in the light guide itself when it is exposed to ionizing radiation. This so called “stem” effect leads to an additional signal which introduces a deviation in the dose rate measurement and reduces the spatial resolution of the system, hence it has to be removed. The current system uses temporal discrimination of the effect for radioluminescence measurements in pulsed radiation fields and modulated optically stimulated luminescence for continuous irradiation conditions. This work gives an overview of the major results and discusses new-found obstacles of the applied methods of stem discrimination.

  19. Measurement of absorbed doses near interfaces, and dose mapping using gas chromic dosimetry media. Vol. 2

    Energy Technology Data Exchange (ETDEWEB)

    Abdel-Rehim, F; Said, F I.A.; Abdel-Fattah, A A [National Centre for Radiation Research and Technology, Atomic Energy Athority, P.O.Box 29 Nasr City, Cairo (Egypt)

    1996-03-01

    Gas chromic dosimetry media is a thin-coated film which has advantages for high-dose radiation dosimetry, and produces high-resolution radiation image for gamma radiation. Therefore, these films were calibrated for the dose range 0.1-50 kGy in terms of increase in absorbance at 600 nm, 400 nm; increase in the area of the absorption spectra in the ranges 395-405 nm and 320-450 nm wave length as a function of absorbed dose in water. The calibrated films were used for measurement of absorbed doses close to metal interface, and dose mapping of the radiation field inside product box during a run for sterilizing surgical gloves at the mega-gamma irradiation facility.7 figs.

  20. COMPUTED TOMOGRAPHY DOSE INDEX MEASUREMENT FOR Hi-ART MEGAVOLTAGE HELICAL CT.

    Science.gov (United States)

    Liu, Minglu; Wang, Yunlai; Liao, Xiongfei

    2016-11-01

    On-line megavoltage computed tomography (MVCT) images are used to verify patient daily set-up in Hi-ART helical TomoTherapy unit. To evaluate the patient dose from MVCT scanning in image guidance, weighted computed tomography (CT) dose index (CTDI w ) was measured with PTW TM30009 CT pencil chamber in head and body phantoms for slice thicknesses of 2, 4 and 6 mm with different scan lengths. Dose length products (DLPs) were subsequently calculated. The CTDI w and DLP were compared with XVI kV CBCT and Brilliance simulator CT for routine clinical protocols. It was shown that CTDI and DLP had close relationship with the slice thickness and the scan length. The dose distribution in the transversal plane was very inhomogeneous due to the attenuation of the couch. Patient dose from MVCT was lower than XVI CBCT for the head scan, while larger for body scan. CTDI w , which is measured easily and reproducibly, can be used to assess the patient dose in MVCT. Regular measurement should be performed in QA & QC programmes. Appropriate slice thickness and scan range should be chosen to reduce the patient dose. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  1. Measurements of cosmic-ray doses in commercial airline cabins

    International Nuclear Information System (INIS)

    Okano, M.; Fujitaka, K.; Izumo, K.

    1996-01-01

    Cosmic radiation doses which aircrew and air passengers receive in airplanes have been calling attention in many countries especially in the last decade. In this relation, various types of information had been reported on cosmic radiation intensity. In Japan, the cosmic radiation intensity had been measured in commercial airline cabins as well as chartered flights. While the intensity depends on altitude, geomagnetic latitude (or cutoff rigidity), and temporal variation of the solar activity, their doses are often speculated based on paper records on airflights combined with the intensity-altitude relationship. In this study, however, efforts were made to estimate more realistic integrated doses in airline cabins based on actual on-board measurements which had been conducted several dozens of times in each year (e.g., 45 times in 1994 and 27 times in 1995). (author)

  2. Technology Development for Radiation Dose Measurement and Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bong Hwan; Chang, S. Y.; Lee, T. Y. (and others)

    2007-06-15

    The correction factors essential for the operation of In-Vivo counting system were produced and implemented into a field operation for the improvement of accuracy in measurement of the radioactivity inside a human body. The BiDAS2007 code which calculate an internal dose was developed by upgrading the former code prepared in the previous stage of this project. The method of using the multibioassy data, the maximum likelihood function and the Bayesian statistics were established to an internal dose based on the measurement data of radioactivity, intakes and retention of radioactivity in a human body and it can improve the accuracy in estimation of the intakes of radioactivity and the committed effective dose equivalent. In order to solve the problem of low detection efficiency of the conventional Bonner Sphere (BS) to a high energy neutron, the extended BS's were manufactured and the technique for neutron field spectrometry was established. The fast neutron and gamma spectrometry system with a BC501A scintillation detector was also prepared. Several neutron fluence spectra at several nuclear facilities were measured and collected by using the extended BS. The spectrum weighted responses of some neutron monitoring instruments were also derived by using these spectra and the detector response functions. A high efficient TL material for the neutron personal dosimeter was developed. It solved the main problem of low thermal stability and high residual dose of the commercial TLDs and has the sensitivity to neutron and to gamma radiation with 40 and 10 times higher respectively than them.

  3. FBX dosimetry for point dose measurements in head and neck cancer patients

    International Nuclear Information System (INIS)

    Balraj, A.; Thakur, P.K.; Bhatnagar, S.; Vidyasagar, P.B.; Nirhali, Amit; Semwal, M.K.

    2007-01-01

    FBX dosimeter is mainly based on the determination of the radiation dose from the chemical changes produced in an irradiated medium, which can be measured by Spectrophotometry or Colorimetry, for which adequate FBX solution of 2 ml required for measuring the optical density (OD). To measure the point dose using 2 ml solution may lead to error in the measured dose since the solution may occupy 2 cc volume of the point measured. In head and neck carcinoma patients, the treatment area involves curvatures. Fixing 2 ml vial at the body surface is difficult and leads to give wrong readings. In this study we have measured the entrance and exit dose by filling 0.5 ml solution in a flexible catheter and placed at a point in the patient body surface during the radiation treatment. The solution was diluted adding 1.5 ml distilled water to measure the OD in the colorimeter

  4. Surface dose measurements and comparison of unflattened and flattened photon beams

    Directory of Open Access Journals (Sweden)

    Ashokkumar Sigamani

    2016-01-01

    Full Text Available The purpose of this study was to evaluate the central axis dose in the build-up region and the surface dose of a 6 MV and 10 MV flattened photon beam (FB and flattening filter free (FFF therapeutic photon beam for different square field sizes (FSs for a Varian Truebeam linear accelerator using parallel-plate ionization chamber and Gafchromic film. Knowledge of dosimetric characteristics in the build-up region and surface dose of the FFF is essential for clinical care. The dose measurements were also obtained empirically using two different commonly used dosimeters: a p-type photon semiconductor dosimeter and a cylindrical ionization chamber. Surface dose increased linearly with FS for both FB and FFF photon beams. The surface dose values of FFF were higher than the FB FSs. The measured surface dose clearly increases with increasing FS. The FFF beams have a modestly higher surface dose in the build-up region than the FB. The dependence of source to skin distance (SSD is less significant in FFF beams when compared to the flattened beams at extended SSDs.

  5. Indoor gamma dose measurements in Gudalore (India) using TLD

    International Nuclear Information System (INIS)

    Sivakumar, R.; Selvasekarapandian, S.; Mugunthamanikandan, N.; Raghunath, V.M.

    2002-01-01

    Indoor gamma radiation dose rates were measured inside residential buildings in Gudalore using a CaSO 4 : Dy thermoluminescent dosimeter for 1 year . Significant seasonal variations are observed. The highest dose rate is observed during summer and the lowest in winter. The dose rates observed are between 77.9 and 229.3 nGy h -1 and may be attributed to the type of building materials used in the dwellings monitored. The calculated mean annual effective dose equivalent rates range between 477.6 μSv y -1 , for the inhabitants of mud houses to 1406.3 μSv y -1 , for those living in terrace houses made of cement and brick

  6. Dosimetric evaluation of the OneDoseTM MOSFET for measuring kilovoltage imaging dose from image-guided radiotherapy procedures.

    Science.gov (United States)

    Ding, George X; Coffey, Charles W

    2010-09-01

    The purpose of this study is to investigate the feasibility of using a single-use dosimeter, OneDose MOSFET designed for in vivo patient dosimetry, for measuring the radiation dose from kilovoltage (kV) x rays resulting from image-guided procedures. The OneDose MOSFET dosimeters were precalibrated by the manufacturer using Co-60 beams. Their energy response and characteristics for kV x rays were investigated by using an ionization chamber, in which the air-kerma calibration factors were obtained from an Accredited Dosimetry Calibration Laboratory (ADCL). The dosimetric properties have been tested for typical kV beams used in image-guided radiation therapy (IGRT). The direct dose reading from the OneDose system needs to be multiplied by a correction factor ranging from 0.30 to 0.35 for kilovoltage x rays ranging from 50 to 125 kVp, respectively. In addition to energy response, the OneDose dosimeter has up to a 20% reduced sensitivity for beams (70-125 kVp) incident from the back of the OneDose detector. The uncertainty in measuring dose resulting from a kilovoltage beam used in IGRT is approximately 20%; this uncertainty is mainly due to the sensitivity dependence of the incident beam direction relative to the OneDose detector. The ease of use may allow the dosimeter to be suitable for estimating the dose resulting from image-guided procedures.

  7. Measurements of eye lens doses in interventional cardiology using OSL and electronic dosemeters

    International Nuclear Information System (INIS)

    Sanchez, R.M.; Vano, E.; Fernandez, J.M.; Ginjaume, M.; Duch, M.A.

    2014-01-01

    The purpose of this paper is to test the appropriateness of OSL and electronic dosemeters to estimate eye lens doses at interventional cardiology environment. Using TLD as reference detectors, personal dose equivalent was measured in phantoms and during clinical procedures. For phantom measurements, OSL dose values resulted in an average difference of 215 % vs. TLD. Tests carried out with other electronic dosemeters revealed differences up to ±20 % versus TLD. With dosemeters positioned outside the goggles and when TLD doses were >20 μSv, the average difference OSL vs. TLD was 29 %. Eye lens doses of almost 700 μSv per procedure were measured in two cases out of a sample of 33 measurements in individual clinical procedures, thus showing the risk of high exposure to the lenses of the eye when protection rules are not followed. The differences found between OSL and TLD are acceptable for the purpose and range of doses measured in the survey (authors)

  8. Determinants of radiological dose from Sr and Cs accumulated by tropical freshwater fish

    International Nuclear Information System (INIS)

    Twining, J.R.; Markich, S.J.; Ferris, J.M.

    1998-01-01

    Recent studies of the bioaccumulation of strontium and caesium by tropical freshwater fish were in some ways consistent with temperate data. For example, biodistribution of radionuclides and the influence of chemical analogues Ca and K were in general agreement with earlier data. However, in other matters there were systematic inconsistencies when compared with the standard IAEA models. These differences gave rise to transfer (concentration) factors for both Cs and Sr that were approximately an order of magnitude below the expected values based on temperate data (e.g. 13 and 0.7 compared with 440 and 4.7 respectively). Compatible results were found for a range of tropical species studied by different investigators. In this presentation, some of the factors believed to influence bioaccumulation, and hence radiological dose, in tropical environments are discussed in relation to the above findings. These factors include: water physico-chemistry, temperature, fish size and physiology, whether or not the data were acquired from field or laboratory studies, and how the studies were carried out. Critical group exposure pathways in tropical environments and the benefits and shortcomings of applying default temperate models of Cs and Sr accumulation by freshwater fish are also discussed. (author)

  9. Dose rate effect on the yield of radiation induced response with thermal fading

    International Nuclear Information System (INIS)

    Chernov, V.; Rogalev, B.; Barboza-Flores, M.

    2005-01-01

    A model describing the dependences of the accumulation of thermally unstable radiation induced defects on the dose and dose rate is proposed. The model directly takes into account the track nature of the ionizing radiation represented as accumulation processes of defects in tracks averaged over a crystal volume considering various degrees of overlapping in space and time. The accumulation of the defects in the tracks is phenomenologically described. General expressions are obtained that allows radiation yield simulation of defects involving known creation and transformation processes. The cases considered, of linear accumulation (constant increment of the defects in tracks) and accumulation with saturation (complete saturation of the defects in one track), lead to a set of linear dose dependences with saturation, which are routinely used in luminescence and ESR dating. The accumulation, with increase of sensitivity in regions overlapped by two or more tracks, gave a set of dose dependences, from linear-sublinear-linear-saturation, distinctive of quartz up to linear-supralinear-linear-saturation. It is shown that the effect of the dose rate on dose dependences is determined by a dimensionless parameter a=Pτ/D0, where P is the dose rate, τ is the defect lifetime and D0 is the track dose. At a-bar 1 the dose rate influences basically the accumulation of thermally unstable defects. In the reverse case the dose dependences did not seems to be influenced by the dose rate

  10. Gamma and electron high dose dosimetry with rad-hard Si diodes

    International Nuclear Information System (INIS)

    Pascoalino, Kelly Cristina da Silva

    2014-01-01

    In this work the main dosimetric characteristics of rad-hard Float Zone (FZ) and magnetic Czochralski (MCz) diodes to electrons (1.5 MeV) and gamma ( 60 Co) radiation are evaluated. The dosimetric system proposed is based on electrical current measurements due to radiation interactions on the devices. The batch response uniformity was studied for the n-type FZ diodes irradiated with gamma rays. The coefficient of variation of the current measurement was about 1.25% at 5 kGy of accumulated dose. A sensitivity decrease with the increase of the accumulated dose (Total Ionizing Dose - TID) was observed for both FZ and MCz diodes. For gamma irradiation, these effect is more pronounced for n-type or smaller resistivity diodes. Two types of dosimetric probe were used on the electron irradiation procedures, one of them specially designed to avoid the deterioration of the electrical contacts and the diodes metallization. The sensitivity of the preirradiated FZ and MCz diodes fell about 10% and 40%, respectively, during electron irradiation at 1.25 MGy of accumulated dose. The effect of electron radiation damage on the electrical properties of the diodes was studied by the means of leakage current and capacitance measurements as a function of bias voltage. The leakage current increases with the accumulated dose but does not contributes significantly to the current signal, since the diodes are operated in photovoltaic mode, without bias voltage. For the MCz diode no change in the full depletion voltage was observed, which indicates its higher tolerance to radiation-induced damage, as expected. During electron irradiation the temperature increases and in order to determine its influence for the current signals, the leakage current values were extrapolated up to 35 °C. The contribution does not exceed 0.1% for FZ and MCz diodes. The effect of the radiation type, electrons or gamma rays, on the pre dose procedures was analyzed for the FZ n-type device and was observed that the

  11. Measurement of radiation dose in paediatric micturating cystourethrography

    International Nuclear Information System (INIS)

    Hassan, N. E. A.

    2013-06-01

    Paediatrics and children have been recognized that they have a higher risk of developing cancer from the radiation than adults. Therefor, increased attention has been directed towards the dose to the patients. Micturating Cystourethrography (MCU) is a commonly use ed fluoroscopic procedure in children and commonly used to detect the vesicoureteric reflux (VUR) and show urethral and bladder and abnormalities. This study aims to measure the pediatric patients undergoing MCU. The study was carried out in two hospitals in Khartoum. The entrance surface dose (ESD) was determined determined by indirect method for 45 children. Furthermore, the mean ESD, sd and range resulting from MCU procedures has been estimated to be 0.7±.5 (0.2-2.5) mGy for the total patient population. The radiation dose to the patients is well within established safety limits, in the light of the current practice. The radiation dose results of this study are appropriate for adoption as the local initial dose reference level (DRL) value for this technique. The data presented in this study showed our doses to be approximately 50% lower than the lower mean values presented in the literature.(Author)

  12. Developing a single-aliquot protocol for measuring equivalent dose in biogenic carbonates

    International Nuclear Information System (INIS)

    Stirling, R.J.; Duller, G.A.T.; Roberts, H.M.

    2012-01-01

    Exploiting biogenic carbonates as thermoluminescence dosimeters requires an understanding of trap kinetics and an appropriate sequence with which to measure equivalent dose. The trap kinetics of two high temperature peaks (peaks II and III) from calcitic snail opercula have been investigated resulting in the calculation of lifetimes of 7.4 × 10 7 and 1.4 × 10 11 years for the two peaks respectively. Two measurement sequences, based upon changes in the application and measurement of a test dose, have been applied to peaks II and III, and though both methods were equally successful in dose recovery and production of a dose response curve some differences were observed. Primarily, the use of method 1 lead to dose dependant sensitivity change implying competition effects occurring during irradiation; method 2 did not experience this phenomenon. As a consequence method 2 was chosen as the most appropriate protocol for single-aliquot dating of this material. When assessing the TL behaviour of the two peaks, peak II performed poorly in dose recovery experiments recovering a dose 60–100% larger than that applied. Disproportionate growth of peak II in response to a beta dose applied prior to measurement, compared to growth following regeneration doses indicated that peak II was not suitable for use in single-aliquot protocols. However, dose recovery results for peak III were all within errors of unity of the given dose, and peak III was therefore chosen as the most appropriate peak for TL dosimetry in these single-aliquot procedures. The lifetime of charge in peak III is sufficient to date over many millions of years, and furthermore using the chosen method 2 the dose response curve has a D 0 of 3,250 ± 163 Gy allowing dating to over 3 million years.

  13. Polymer gel dosimetry for synchrotron stereotactic radiotherapy and iodine dose-enhancement measurements

    International Nuclear Information System (INIS)

    Boudou, C; Tropres, I; Rousseau, J; Lamalle, L; Adam, J F; Esteve, F; Elleaume, H

    2007-01-01

    Synchrotron stereotactic radiotherapy (SSR) is a radiotherapy technique that makes use of the interactions of monochromatic low energy x-rays with high atomic number (Z) elements. An important dose-enhancement can be obtained if the target volume has been loaded with a sufficient amount of a high-Z element, such as iodine. In this study, we compare experimental dose measurements, obtained with normoxic polymer gel (nPAG), with Monte Carlo computations. Gels were irradiated within an anthropomorphic head phantom and were read out by magnetic resonance imaging. The dose-enhancement due to the presence of iodine in the gel (iodine concentration: 5 and 10 mg ml -1 ) was measured at two radiation energies (35 and 80 keV) and was compared to the calculated factors. nPAG dosimetry was shown to be efficient for measuring the sharp dose gradients produced by SSR. The agreement between 3D gel dosimetry and calculated dose distributions was found to be within 4% of the dose difference criterion and a distance to agreement of 2.1 mm for 80% of the voxels. Polymer gel doped with iodine exhibited higher sensitivity, in good agreement with the calculated iodine-dose enhancement. We demonstrate in this preliminary study that iodine-doped nPAG could be used for measuring in situ dose distributions for iodine-enhanced SSR treatment

  14. Electron scattering effects on absorbed dose measurements with LiF-dosemeters

    International Nuclear Information System (INIS)

    Bertilsson, G.

    1975-10-01

    The investigation deals with absorbed dose measurements with solid wall-less dosemeters. Electron scattering complicates both measurement of absorbed dose and its theoretical interpretation. The introduction of the dosemeter in a medium causes perturbations of the radiation field. This perturbation and its effect on the distribution of the absorbed dose inside the dosemeter is studied. Plane-parallel LiF-teflon dosemeters (0.005 - 0.1 g.cm -2 ) are irradiated by a photon beam ( 137 Cs) in different media. The investigation shows that corrections must be made for perturbations caused by electron scattering phenomena. Correction factors are given for use in accurate absorbed dose determinations with thermoluminescent dosemeters. (Auth.)

  15. Measurement system for depth dose distribution in cancer therapy

    International Nuclear Information System (INIS)

    Nishizawa, Hiroshi; Fujiwara, Hirotsugu; Tsutaka, Yoshikazu; Ikeda, Ikuo

    1999-01-01

    An accurate estimation of an absorbed dose distribution in human tissue is indispensable to efficiently perform radiotherapy in humans. Previously, various methods for such estimation have been developed, however, there is some problem in those methods, it takes too long times (3-4 hours) to determine the absorbed dose distribution through scanning by ionization chamber in water phantom. So, a determination system of depth dose was developed with an aim to determine the absorbed dose of X-ray or electron beam in materials similar to human body. This system was composed of a detector including scintillation fibers which allows emission due to radio-interaction, CCD camera for determination of light distribution of the emission and personal computer for data processing. Though the accuracy of this system was ±2% similar to that of the conventional measuring method, measuring time was reduced to almost 5 min, markedly shorter than that of the conventional water phantom (3-4 hours). The efficacy of works including the adjustment of irradiation system, planning, etc. would be improved by application of this system. (M.N.)

  16. Characteristics of dosemeter types for skin dose measurements in practice

    International Nuclear Information System (INIS)

    Van, D. J.; Bosmans, H.; Marchal, G.; Wambersie, A.

    2005-01-01

    A growing number of papers report deterministic effects in the skin of patients who have undergone interventional radiological procedures. Dose measurements, and especially skin dose measurements, are therefore increasingly important. Methods and acceptable dosemeters are, however, not clearly defined. This paper is the result of a literature overview with regard to assessing the entrance skin dose during radiological examinations by putting a dosemeter on the patient's skin. The relevant intrinsic characteristics, as well as some examples of clinical use of the different detector types, are presented. In this respect, thermoluminescence, scintillation, semiconductor and film dosemeters are discussed and compared with respect to their practical use. (authors)

  17. Determining clinical photon beam spectra from measured depth dose with the Cimmino algorithm

    International Nuclear Information System (INIS)

    Bloch, P.; Altschuler, M.D.; Bjaerngard, B.E.; Kassaee, A.; McDonough, J.

    2000-01-01

    A method to determine the spectrum of a clinical photon beam from measured depth-dose data is described. At shallow depths, where the range of Compton-generated electrons increases rapidly with photon energy, the depth dose provides the information to discriminate the spectral contributions. To minimize the influence of contaminating electrons, small (6x6cm2 ) fields were used. The measured depth dose is represented as a linear combination of basis functions, namely the depth doses of monoenergetic photon beams derived by Monte Carlo simulations. The weights of the basis functions were obtained with the Cimmino feasibility algorithm, which examines in each iteration the discrepancy between predicted and measured depth dose. For 6 and 15 MV photon beams of a clinical accelerator, the depth dose obtained from the derived spectral weights was within about 1% of the measured depth dose at all depths. Because the problem is ill conditioned, solutions for the spectrum can fluctuate with energy. Physically realistic smooth spectra for these photon beams appeared when a small margin (about ±1%) was attributed to the measured depth dose. The maximum energy of both derived spectra agreed with the measured energy of the electrons striking the target to within 1 MeV. The use of a feasibility method on minimally relaxed constraints provides realistic spectra quickly and interactively. (author)

  18. Dose rate measurement of a cobalt source 'Issledovatel' by means of Fricke dosimeter

    CERN Document Server

    Peimel-Stuglik, Z

    2001-01-01

    The results of measurements leading to the elaboration of a reliable and accurate dose rate determination for a cobalt irradiator 'Issledovatel' were presented. The dose measurements were done by means of classic Fricke dosimeter. The conclusions from measurements can be useful also for the dosimetry of other kinds of cobalt irradiators. The measurements were performed by a newly employed Laboratory for Measurements of Technological Doses staff and were a practical test of their proficiency in gamma ray dosimetry.

  19. Evaluation of the absorbed doses in conditions of external and internal contamination with radionuclides

    International Nuclear Information System (INIS)

    Milivojevic, K.; Stojanovic, D.; Markovic, P.

    1981-01-01

    In experimental conditions of contamination with radionuclides of the skin and skin injuries, an evaluation of the degree of local irradiation in decontamined region and doses absorbed in organs of selective accumulating was carried out by use of mathematical models and tissue-equivalent thermoluminescent dosemeters. The evaluation of the absorbed doses based on conception, that in adequate analyses of decontamination effect, as a most efficient medico-prophilactic measure from local and total irradiation, should be taken into account the total body burden of the penetrated radionuclide, selective accumulating in critical organs or tissues, as well as the residual radioactivity in decontaminated region. (author)

  20. Assessment of dose measurement uncertainty using RisoScan

    International Nuclear Information System (INIS)

    Helt-Hansen, Jakob; Miller, Arne

    2006-01-01

    The dose measurement uncertainty of the dosimeter system RisoScan, office scanner and Riso B3 dosimeters has been assessed by comparison with spectrophotometer measurements of the same dosimeters. The reproducibility and the combined uncertainty were found to be approximately 2% and 4%, respectively, at one standard deviation. The subroutine in RisoScan for electron energy measurement is shown to give results that are equivalent to the measurements with a scanning spectrophotometer

  1. Some measurements of doses to patients from dental X-rays

    International Nuclear Information System (INIS)

    Woehni, T.

    1976-01-01

    Some measurements of doses to patients from conventional dental radiography and orthopantomography are presented. Doses to the red bone marrow are calculated. The bone marrow doses from two different exposures, Maxilla incisor and Molar bite-wing, were calculated to be 0.4 and 1.0 mrad respectively. The average dose to red bone marrow from a full-mouth examination (10 exposures) was 0.7 mrad/exposure. An orthopantomographic examination involved 2 mrad to the bone marrow. The greatest doses from an orthopantomographic examination were found around the lateral rotational axis, namely 700 mrad. The dose distributions from the two different cone lengths did not differ as much as expected, mainly due to scattered radiation. (Auth.)

  2. Some measurements of doses to patients from dental X-rays

    Energy Technology Data Exchange (ETDEWEB)

    Woehni, T [Statens Institutt for Straalehygiene, Oslo (Norway)

    1976-11-01

    Some measurements of doses to patients from conventional dental radiography and orthopantomography are presented. Doses to the red bone marrow are calculated. The bone marrow doses from two different exposures, Maxilla incisor and Molar bite-wing, were calculated to be 0.4 and 1.0 mrad respectively. The average dose to red bone marrow from a full-mouth examination (10 exposures) was 0.7 mrad/exposure. An orthopantomographic examination involved 2 mrad to the bone marrow. The greatest doses from an orthopantomographic examination were found around the lateral rotational axis, namely 700 mrad. The dose distributions from the two different cone lengths did not differ as much as expected, mainly due to scattered radiation.

  3. Dose effect on the uptake and accumulation of hydroxytyrosol and its metabolites in target tissues in rats.

    Science.gov (United States)

    López de las Hazas, Maria-Carmen; Rubió, Laura; Kotronoulas, Aristotelis; de la Torre, Rafael; Solà, Rosa; Motilva, Maria-José

    2015-07-01

    Hydroxytyrosol (HT) is the most prominent phenolic compound of virgin olive oil and due to its scientifically validated biological activities it is entering to the market as a potentially useful supplement for cardiovascular disease prevention. The aim of the present study was to investigate the relationship between the HT dose intake and its tissue uptake in rats, and thus, providing complementary information in relation to the target-dose relationship. Rats were given a refined olive oil enriched with HT at different doses (1, 10, and 100 mg/kg) and they were sacrificed after 5 h to ensure the cell tissue uptake of HT and its metabolites. Plasma samples and different organs as liver, kidney, heart and brain were obtained, and HT metabolites were analyzed by UPLC-MS/MS. The results showed that HT and its metabolites could be accumulated in a dose-dependent manner basically in the liver, kidney, and brain and were detected in these tissues even at nutritionally relevant human doses. The detection of free HT in liver and kidney was noteworthy. To date, this appears to be the only biologically active form, and thus, it provides relevant information for optimizing the potential applications of HT to prevent certain hepatic and renal diseases. In recent years, HT and its derivatives have led to a great interest from the virgin olive oil producers and manufacturers of nutraceutical supplements. The increasing interest in HT is mainly due to the European Food Safety Agency (EFSA) Panel on Dietetic Products, Nutrition, and Allergies (NDA) scientific opinion that established a cause-and-effect relationship between the consumption of olive oil polyphenols and protection of LDL particles from oxidative damage . Based on this positive opinion, the health claim "Olive oil polyphenols contribute to the protection of blood lipids from oxidative stress" was included in the list of health claims , being the only authorized health claim in the European Union regarding polyphenols

  4. Measurement of patient radiation doses in certain urography procedures

    International Nuclear Information System (INIS)

    Sulieman, A.; Barakat, H.; Zailae, A.; Abuderman, A.; Theodorou, K.

    2015-01-01

    Patients are exposed to significant radiation doses during diagnostic and interventional urological procedures. This study aimed to measure patient entrance surface air kerma (ESAK) and to estimate the effective dose during intravenous urography (IVU), extracorporeal shock-wave lithotripsy (ESWL), and ascending urethrogram (ASU) procedures. ESAK was measured in patients using calibrated thermo luminance dosimeters, GR200A). Effective doses (E) were calculated using the National Radiological Protection Board (NRPB) software. A total of 179 procedures were investigated. 27.9 % of the patients underwent IVU procedures, 27.9 % underwent ESWL procedures and 44.2 % underwent ASU procedures. The mean ESAK was 2.1, 4.18 and 4.9 mGy for IVU, ESWL, and ASU procedures, respectively. Differences in patient ESAK for the same procedure were observed. The mean ESAK values were comparable with those in previous studies. (authors)

  5. Phantom measurements and computed estimates of breast dose with radiotherapy for Hodgkin's lymphoma: dose reduction with the use of the involved field

    International Nuclear Information System (INIS)

    Wirth, A.; Kron, T.; Sorell, G.; Cramb, J.; Wittwer, H.; Sullivan, K.

    2008-01-01

    Full text: The risk of breast cancer following radiotherapy for Hodgkin's lymphoma appears to be dose related. In this study we compared breast dose in an anthropomorphic phantom for conventional 'mantle'; upper mediastinal/bilateral neck (minimantle) and unilateral neck fields, and evaluated the accuracy of computer planned dose estimates for out-of-field doses. For each field, computer-planned breast dose (CPD) estimates were compared with thermolu-minescence dosimetry measurements in five locations within 'breast tissue'. CPD were also compared with ion chamber measurements in a slab phantom. Measured dose and CPD were within 20% of each other up to approximately 10 cm from the field edge. Beyond 10 cm, the CPD underestimated dose by a factor of 2 or more. The minimantle reduced the breast dose by a factor of approximately 10 compared with the mantle treatment. Treating the neck field lowered the breast dose by a further 50% or more. Modern involved-field radiotherapy for lymphoma substantially reduces breast dose compared with mantle fields. Computer dosimetery underestimated dose at larger distances from the field. This needs to be considered if computer dosimetery is used to estimate breast dose and, by extrapolation, breast cancer risk.

  6. Neutron and gamma dose and spectra measurements on the Little Boy replica

    International Nuclear Information System (INIS)

    Hoots, S.; Wadsworth, D.

    1984-01-01

    The radiation-measurement team of the Weapons Engineering Division at Lawrence Livermore National Laboratory (LLNL) measured neutron and gamma dose and spectra on the Little Boy replica at Los Alamos National Laboratory (LANL) in April 1983. This assembly is a replica of the gun-type atomic bomb exploded over Hiroshima in 1945. These measurements support the National Academy of Sciences Program to reassess the radiation doses due to atomic bomb explosions in Japan. Specifically, the following types of information were important: neutron spectra as a function of geometry, gamma to neutron dose ratios out to 1.5 km, and neutron attenuation in the atmosphere. We measured neutron and gamma dose/fission from close-in to a kilometer out, and neutron and gamma spectra at 90 and 30 0 close-in. This paper describes these measurements and the results. 12 references, 13 figures, 5 tables

  7. Real-time personal dose measurement and management system

    International Nuclear Information System (INIS)

    Zhang Zhiyong; Cheng Chang; Liu Zhengshan; Yang Huating; Deng Changming; Zhang Xiu; Guo Zhanjie

    2001-01-01

    The composition and design of a real-time personal dose measurement and management system are described. Accordingly, some pertinent hardware circuits and software codes including their operation modes are presented

  8. Measurement of exposure dose rate by TLD in 60Co garden

    International Nuclear Information System (INIS)

    Fan Chengfang; Li Pinfang; Wu Maoliang; Zhao Quan

    1987-01-01

    The use of TLD method to measure exposure dose rate in 60 Co garden is described. As compared with chemical dosimetry, the relative deviation of measurement would not exceed 10%. The good repeatability has been proved by comparing the measurements of different times and distances with correction of decay law and 1/1 2 law. Besides, the distribution of exposure dose rate was influenced by scattering of the living plants

  9. Indoor gamma dose measurements in Gudalore (India) using TLD

    Energy Technology Data Exchange (ETDEWEB)

    Sivakumar, R.; Selvasekarapandian, S. E-mail: spandian@bharathi.ernet.in; Mugunthamanikandan, N.; Raghunath, V.M

    2002-06-01

    Indoor gamma radiation dose rates were measured inside residential buildings in Gudalore using a CaSO{sub 4} : Dy thermoluminescent dosimeter for 1 year . Significant seasonal variations are observed. The highest dose rate is observed during summer and the lowest in winter. The dose rates observed are between 77.9 and 229.3 nGy h{sup -1} and may be attributed to the type of building materials used in the dwellings monitored. The calculated mean annual effective dose equivalent rates range between 477.6 {mu}Sv y{sup -1}, for the inhabitants of mud houses to 1406.3 {mu}Sv y{sup -1}, for those living in terrace houses made of cement and brick.

  10. Organ dose evaluation for CT scans based on in-phantom measurements

    International Nuclear Information System (INIS)

    Liu Haikuan; Zhuo Weihai; Chen Bo; Yi Yanling; Li Dehong

    2009-01-01

    Objective: To explore the organ doses and their distributions in different projections of CT scans. Methods: The CT values were measured and the linear absorption coefficients were derived for the main organs of the anthropomorphic phantom to compare with the normal values of human beings. The radiophotoluminescent glass dosimeters were set into various tissues or organs of the phantom for mimic measurements of the organ doses undergoing the head, chest, abdomen and pelvis CT scans, respectively. Results: The tissue equivalence of the phantom used in this study was good. The brain had the largest organ dose undergoing the head CT scan. The organ doses in thyroid, breast, lung and oesophagus were relatively large in performing the chest CT scan, while the liver, stomach, colon and lung had relatively hrge organ doses in abdomen CT practice. The doses in bone surface and colon exceeded by 50 mGy in a single pelvis CT scan. Conclusions: The organ doses and their distributions largely vary with different projections of CT scans. The organ doses of colon, bone marrow,gonads and bladder are fairly large in performing pelvis CT scan, which should be paid attention in the practice. (authors)

  11. Polystyrene calorimeter for electron beam dose measurements

    DEFF Research Database (Denmark)

    Miller, A.

    1995-01-01

    Calorimeters from polystrene have been constructed for dose measurement at 4-10 MeV electron accelerators. These calorimeters have been used successfully for a few years, and polystyrene calorimeters for use at energies down to 1 MeV and being tested. Advantage of polystyrene as the absorbing...

  12. Radiation dose measurements during kilovoltage-cone beam computed tomography imaging in radiotherapy

    Directory of Open Access Journals (Sweden)

    A Sathish Kumar

    2016-01-01

    Conclusion: Radiation dose to the eye, breast, and the surface of the pelvis have been arrived at during CBCT. The doses measured on patients agreed closely with those measured on humanoid phantom and with published values.

  13. Radiation-induced effects on the mechanical properties of natural ZrSiO4: double cascade-overlap damage accumulation

    Science.gov (United States)

    Beirau, Tobias; Nix, William D.; Pöllmann, Herbert; Ewing, Rodney C.

    2017-11-01

    Several different models are known to describe the structure-dependent radiation-induced damage accumulation process in materials (e.g. Gibbons Proc IEEE 60:1062-1096, 1972; Weber Nuc Instr Met Phys Res B 166-167:98-106, 2000). In the literature, two different models of damage accumulation due to α-decay events in natural ZrSiO4 (zircon) have been described. The direct impact damage accumulation model is based on amorphization occurring directly within the collision cascade. However, the double cascade-overlap damage accumulation model predicts that amorphization will only occur due to the overlap of disordered domains within the cascade. By analyzing the dose-dependent evolution of mechanical properties (i.e., Poisson's ratios, compliance constants, elastic modulus, and hardness) as a measure of the increasing amorphization, we provide support for the double cascade-overlap damage accumulation model. We found no evidence to support the direct impact damage accumulation model. Additionally, the amount of radiation damage could be related to an anisotropic-to-isotropic transition of the Poisson's ratio for stress along and perpendicular to the four-fold c-axis and of the related compliance constants of natural U- and Th-bearing zircon. The isotropification occurs in the dose range between 3.1 × and 6.3 × 1018 α-decays/g.

  14. Radiation-induced effects on the mechanical properties of natural ZrSiO4: double cascade-overlap damage accumulation

    Science.gov (United States)

    Beirau, Tobias; Nix, William D.; Pöllmann, Herbert; Ewing, Rodney C.

    2018-05-01

    Several different models are known to describe the structure-dependent radiation-induced damage accumulation process in materials (e.g. Gibbons Proc IEEE 60:1062-1096, 1972; Weber Nuc Instr Met Phys Res B 166-167:98-106, 2000). In the literature, two different models of damage accumulation due to α-decay events in natural ZrSiO4 (zircon) have been described. The direct impact damage accumulation model is based on amorphization occurring directly within the collision cascade. However, the double cascade-overlap damage accumulation model predicts that amorphization will only occur due to the overlap of disordered domains within the cascade. By analyzing the dose-dependent evolution of mechanical properties (i.e., Poisson's ratios, compliance constants, elastic modulus, and hardness) as a measure of the increasing amorphization, we provide support for the double cascade-overlap damage accumulation model. We found no evidence to support the direct impact damage accumulation model. Additionally, the amount of radiation damage could be related to an anisotropic-to-isotropic transition of the Poisson's ratio for stress along and perpendicular to the four-fold c-axis and of the related compliance constants of natural U- and Th-bearing zircon. The isotropification occurs in the dose range between 3.1 × and 6.3 × 1018 α-decays/g.

  15. Pediatric patient and staff dose measurements in barium meal fluoroscopic procedures

    Science.gov (United States)

    Filipov, D.; Schelin, H. R.; Denyak, V.; Paschuk, S. A.; Porto, L. E.; Ledesma, J. A.; Nascimento, E. X.; Legnani, A.; Andrade, M. E. A.; Khoury, H. J.

    2015-11-01

    This study investigates patient and staff dose measurements in pediatric barium meal series fluoroscopic procedures. It aims to analyze radiographic techniques, measure the air kerma-area product (PKA), and estimate the staff's eye lens, thyroid and hands equivalent doses. The procedures of 41 patients were studied, and PKA values were calculated using LiF:Mg,Ti thermoluminescent dosimeters (TLDs) positioned at the center of the patient's upper chest. Furthermore, LiF:Mg,Cu,P TLDs were used to estimate the equivalent doses. The results showed a discrepancy in the radiographic techniques when compared to the European Commission recommendations. Half of the results of the analyzed literature presented lower PKA and dose reference level values than the present study. The staff's equivalent doses strongly depends on the distance from the beam. A 55-cm distance can be considered satisfactory. However, a distance decrease of ~20% leads to, at least, two times higher equivalent doses. For eye lenses this dose is significantly greater than the annual limit set by the International Commission on Radiological Protection. In addition, the occupational doses were found to be much higher than in the literature. Changing the used radiographic techniques to the ones recommended by the European Communities, it is expected to achieve lower PKA values ​​and occupational doses.

  16. Multilayer detector for skin absorbed dose measuring

    International Nuclear Information System (INIS)

    Osanov, D.P.; Panova, V.P.; Shaks, A.I.

    1985-01-01

    A method for skin dosimetry based on utilization of multilayer detectors and permitting to estimate distribution of absorbed dose by skin depth is described. The detector represents a set of thin sensitive elements separated by tissue-equivalent absorbers. Quantitative evaluation and forecasting the degree of radiation injury of skin are determined by the formula based on determination of the probability of the fact that cells are not destroyed and they can divide further on. The given method ensures a possibility of quantitative evaluation of radiobiological effect and forecasting clinical consequences of skin irradiation by results of corresponding measurements of dose by means of the miultilayer detector

  17. Composite depth dose measurement for total skin electron (TSE) treatments using radiochromic film

    International Nuclear Information System (INIS)

    Gamble, Lisa M; Farrell, Thomas J; Jones, Glenn W; Hayward, Joseph E

    2003-01-01

    Total skin electron (TSE) radiotherapy is routinely used to treat cutaneous T-cell lymphomas and can be implemented using a modified Stanford technique. In our centre, the composite depth dose for this technique is achieved by a combination of two patient positions per day over a three-day cycle, and two gantry angles per patient position. Due to patient morphology, underdosed regions typically occur and have historically been measured using multiple thermoluminescent dosimeters (TLDs). We show that radiochromic film can be used as a two-dimensional relative dosimeter to measure the percent depth dose in TSE radiotherapy. Composite depth dose curves were measured in a cylindrical, polystyrene phantom and compared with TLD data. Both multiple films (1 film per day) and a single film were used in order to reproduce a realistic clinical scenario. First, three individual films were used to measure the depth dose, one per treatment day, and then compared with TLD data; this comparison showed a reasonable agreement. Secondly, a single film was used to measure the dose delivered over three daily treatments and then compared with TLD data; this comparison showed good agreement throughout the depth dose, which includes doses well below 1 Gy. It will be shown that one piece of radiochromic film is sufficient to measure the composite percent depth dose for a TSE beam, hence making radiochromic film a suitable candidate for monitoring underdosed patient regions

  18. Neutron dose measurements with the GSI ball at high energy accelerators

    International Nuclear Information System (INIS)

    Fehrenbacher, G.; Gutermuth, F.; Radon, T.; Kozlova, E.

    2005-01-01

    Full text: At high energy particle accelerators the production of neutron radiation dominates radiation protection. For the radiation survey at accelerators there is a need for reliable detection systems (passive radiation monitors), which can measure the dose for a wide range of neutron energies independently on the beam pulse structure of the produced radiation. In this work a passive neutron dosemeter for the measurement of the ambient dose equivalent is presented. The dosemeter is suitable for measurements of the emerging neutron radiation at accelerators for the whole energy range up to about 10 GeV. The dosemeter consists of a polyethylene sphere, TL elements (pairs of TLD600/700) and an additional lead layer (PE/Pb) in neutron fields at high energy accelerators is investigated in this work. Results of dose measurements which were performed in realistic neutron fields at the high energy accelerator SPS at CERN (CERF facility) and in Cave A at the heavy ion synchrotron SIS at GSI are presented. The results of these measurements are compared with the expected dose values from the neutron spectra determined for the measurement positions at CERF and in Cave A (FLUKA) and with the dosemeter response derived by the calculated response functions (FLUKA) folded with the neutron spectra. The comparisons show that the additional lead layer in the PE/Pb-sphere improves significantly the response of the dosemeter. The response of the PE/Pb-sphere is 40 to 50 % higher at CERF and Cave A in comparison to the bare PE-sphere. At CERF the dose values of the PE/Pb-sphere is about 25 % lower than the expected dose value, whilst for Cave A, a rather good agreement was found (2 % deviation). (author)

  19. Measurement of ambient dose equivalent H*(10) and directional dose equivalent H'(0.07) with pocket sized survey meters

    International Nuclear Information System (INIS)

    Iwatschenko, Michael

    2008-01-01

    Full text: In many parts of the world, predominantly in Europe, small sized survey meters based on Geiger-Mueller or proportional counters are widely used for dose rate and dose equivalent rate measurements, while in other regions, especially in the U.S., ionisation chambers are preferred for this task. This paper tries to shed some light on the likely reasons for these two diverging instrumental inclinations. Their respective strengths and weaknesses is analyzed in respect to energy response, dose rate measuring range, size, weight and susceptibility to environmental influences. Furthermore the response and limitations regarding the measurement of pulsed radiation (medical X-ray and CT-devices, accelerators, non-destructive testing) is discussed. A newly developed pocket size instrument based on a pan-cake Geiger-Mueller tube is used as an example to explain the capability and flexibility of modern survey meters. The RadEye B20 is a compact multi-purpose dose rate meter and contamination meter for alpha, beta, gamma and X-ray radiation. By virtue of carefully designed multi-layer gamma energy filters, H*(10) (deep dose) or H'(0,07) (shallow dose) measurements from 17 - 1300 keV can be performed. The instrument can even be worn in a belt holster, so that the impact to the mobility of the user is minimized. For emergency response purposes alpha and beta contamination can be discriminated using another optional filter; a simple sample changer adapter can extend the scope of application. Immediate and reproducible counter measurements, e.g. of smear tests can be performed locally. (author)

  20. Accumulation of sucrose in irradiated agricultural products

    International Nuclear Information System (INIS)

    Hayashi, T.

    1986-01-01

    Irradiation of agricultural products with ionizing radiation causes various physiological changes and one of the interesting phenomena is the increase of sucrose in irradiated potatoes. The relationship, however, between sucrose content and irradiation dose was not clarified. The author has made the relationship clear and found out that the sucrose content once enhanced by a high dose of irradiation does not lower during storage for a long period. It has been found that the sucrose accumulation caused by irradiation occurred in sweet potatoes and chestnuts as well as potatoes. In this article the effect of gamma-irradiation on the sucrose content of potato tubers, sweet potato roots and chestnuts will be reviewed and the mechanism of this sucrose accumulation will be discussed

  1. Accumulation of sucrose in irradiated agricultural products

    Energy Technology Data Exchange (ETDEWEB)

    Hayashi, T. [National Food Research Inst., Tsukuba, Ibaraki (Japan)

    1986-03-15

    Irradiation of agricultural products with ionizing radiation causes various physiological changes and one of the interesting phenomena is the increase of sucrose in irradiated potatoes. The relationship, however, between sucrose content and irradiation dose was not clarified. The author has made the relationship clear and found out that the sucrose content once enhanced by a high dose of irradiation does not lower during storage for a long period. It has been found that the sucrose accumulation caused by irradiation occurred in sweet potatoes and chestnuts as well as potatoes. In this article the effect of gamma-irradiation on the sucrose content of potato tubers, sweet potato roots and chestnuts will be reviewed and the mechanism of this sucrose accumulation will be discussed.

  2. The Antiproton Depth Dose Curve Measured with Alanine Detectors

    DEFF Research Database (Denmark)

    Bassler, Niels; Hansen, Johnny Witterseh; Palmans, Hugo

    2008-01-01

    In this paper we report on the measurement of the antiproton depth dose curve, with alanine detectors. The results are compared with simulations using the particle energy spectrum calculated by FLUKA, and using the track structure model of Hansen et Olsen for conversion of calculated dose...... into response. A good agreement was observed between the measured and calculated relative effectiveness although a slight underestimation of the calculated values in the Bragg peak remains unexplained. The model prediction of response of alanine towards heavy charged particles encourages future use...... of the alanine detectors for dosimetry of mixed radiation fields....

  3. Measuring a critical stress for continuous prevention of marine biofouling accumulation with aeration.

    Science.gov (United States)

    Menesses, Mark; Belden, Jesse; Dickenson, Natasha; Bird, James

    2017-10-01

    When cleaning the hull of a ship, significant shear stresses are needed to remove established biofouling organisms. Given that there exists a link between the amount of time that fouling accumulates and the stress required to remove it, it is not surprising that more frequent grooming requires less shear stress. Yet, it is unclear if there is a minimum stress needed to prevent the growth of macrofouling in the limit of continuous grooming. This manuscript shows that single bubble stream aeration provides continuous grooming and prevents biofouling accumulation in regions where the average wall stress exceeds ~0.01 Pa. This value was found by comparing observations of biofouling growth from field studies with complementary laboratory measurements that probe the associated flow fields. These results suggest that aeration and other continuous grooming systems must exceed a wall stress of 0.01 Pa to prevent macrofouling accumulation.

  4. Methodic of the gamma-rays absorbed dose measurements on tooth enamel

    International Nuclear Information System (INIS)

    Linev, S.V.; Muravskij, V.A.; Mashevskij, A.A.; Ugolev, I.I.

    1997-01-01

    The analysis of the metrological aspects of the tooth enamel ESR dosimetry has been done. The sample preparation and measurement methods have been elaborated. The methods have passed metrological certification. The methods include tabletting of the mixture of tooth enamel powder and MnO paramagnetic centres concentration additional standard, two loops of additional irradiation of samples by 1 Gy dose and ESR-spectra measurements, calculation of absorbed dose by maximum likelihood algorithm. The algorithm of dose calculation uses enamel spectrum model with axial anisotropic spin-Hamiltonian based on 126 spectra of enamel samples. The algorithm takes into account spectra of the empty cavity, the tube for a sample, the glue and MnO standard. Certificated ESR-station is based on the ESR-analyser PS-100X. ESR-station provides tooth enamel absorbed dose measurements from 0.05 to 0.25 Gy with error 35%, and from 0.25 to 3 Gy with error 20%. The set of tooth enamel absorbed dose standard samples has been created and certificated for the purposes of ESR-station testing and certification. The set consists of 12 tabletted samples of tooth enamel irradiated by doses from 0.05 to 4 Gy. (authors). 7 refs., 1 tab., 2 figs

  5. Neutron dose and energy spectra measurements at Savannah River Plant

    International Nuclear Information System (INIS)

    Brackenbush, L.W.; Soldat, K.L.; Haggard, D.L.; Faust, L.G.; Tomeraasen, P.L.

    1987-08-01

    Because some workers have a high potential for significant neutron exposure, the Savannah River Plant (SRP) contracted with Pacific Northwest Laboratory (PNL) to verify the accuracy of neutron dosimetry at the plant. Energy spectrum and neutron dose measurements were made at the SRP calibrations laboratory and at several other locations. The energy spectra measurements were made using multisphere or Bonner sphere spectrometers, 3 He spectrometers, and NE-213 liquid scintillator spectrometers. Neutron dose equivalent determinations were made using these instruments and others specifically designed to determine dose equivalent, such as the tissue equivalent proportional counter (TEPC). Survey instruments, such as the Eberline PNR-4, and the thermoluminescent dosimeter (TLD)-albedo and track etch dosimeters (TEDs) were also used. The TEPC, subjectively judged to provide the most accurate estimation of true dose equivalent, was used as the reference for comparison with other devices. 29 refs., 43 figs., 13 tabs

  6. Systematic measurements of whole-body imaging dose distributions in image-guided radiation therapy

    International Nuclear Information System (INIS)

    Hälg, Roger A.; Besserer, Jürgen; Schneider, Uwe

    2012-01-01

    Purpose: The full benefit of the increased precision of contemporary treatment techniques can only be exploited if the accuracy of the patient positioning is guaranteed. Therefore, more and more imaging modalities are used in the process of the patient setup in clinical routine of radiation therapy. The improved accuracy in patient positioning, however, results in additional dose contributions to the integral patient dose. To quantify this, absorbed dose measurements from typical imaging procedures involved in an image-guided radiation therapy treatment were measured in an anthropomorphic phantom for a complete course of treatment. The experimental setup, including the measurement positions in the phantom, was exactly the same as in a preceding study of radiotherapy stray dose measurements. This allows a direct combination of imaging dose distributions with the therapy dose distribution. Methods: Individually calibrated thermoluminescent dosimeters were used to measure absorbed dose in an anthropomorphic phantom at 184 locations. The dose distributions from imaging devices used with treatment machines from the manufacturers Accuray, Elekta, Siemens, and Varian and from computed tomography scanners from GE Healthcare were determined and the resulting effective dose was calculated. The list of investigated imaging techniques consisted of cone beam computed tomography (kilo- and megavoltage), megavoltage fan beam computed tomography, kilo- and megavoltage planar imaging, planning computed tomography with and without gating methods and planar scout views. Results: A conventional 3D planning CT resulted in an effective dose additional to the treatment stray dose of less than 1 mSv outside of the treated volume, whereas a 4D planning CT resulted in a 10 times larger dose. For a daily setup of the patient with two planar kilovoltage images or with a fan beam CT at the TomoTherapy unit, an additional effective dose outside of the treated volume of less than 0.4 mSv and 1

  7. Entrance surface dose measurements in mammography using thermoluminescence technique

    International Nuclear Information System (INIS)

    Rivera, T.; Vega C, H.R.; Manzanares A, E; Azorin, J.; Gonzalez, P.R.

    2007-01-01

    Full text: Of the various techniques that can be used for personnel dosimetry, thermoluminescence dosimetry (TLD) has emerged as a superior technique due to its manifold advantages over other methods of dose estimation. Various phosphors have been therefore investigated regarding their suitability for dosimetry. In this paper, a dosimetry system based on thermally stimulated luminescence (TSL) from zirconium oxide phosphors embedded in polytetrafluorethylene (ZrO 2 +PTFE) was developed for entrance surface doses (ES) measurements in mammography. Small ZrO 2 pellets of 5 mm in diameter and 0.8 mm in thickness were used. The reproducibility of measurements and linearity of ZrO 2 were also studied. The results were compared with those obtained from LiF:Mg,Cu,P usually used for the determination of absorbed dose in mammography. Measurements both per unit air kerma and In vivo were performed using a mammography unit model DMR (General Electric). The results showed that ZrO 2 TLDs can be used for the same X-ray dosimetry applications as LiF:Mg,Cu,P, with each type having the disadvantage of a response dependent on energy, particularly at low energies. These results indicate a considerable potential for use in routine control and In vivo ES measurements in mammography. (Author)

  8. Assessment of micro-dose biplanar radiography in lower limb measurements in children

    International Nuclear Information System (INIS)

    Lerisson, Heloise; Amzallag-Bellenger, Elisa; Cebulski-Delebarre, Aurelie; Boutry, Nathalie; Nectoux, Eric; Herbaux, Bernard; Desmulliez, Geoffrey; Duhamel, Alain; Drumez, Elodie

    2018-01-01

    To evaluate in children microdose protocol compared with low dose for lower limb alignment (LLA) measurements on biplanar radiography. Children 6 years or older were included. Height, weight and hip width were measured prior to imaging. Hip width allowed classifying children into morphotype M1 (width <25 cm), M2 (25-35 cm) or M3 (>35 cm) corresponding to predefined acquisition parameters (kV, mA, tube speed). Micro- and low-dose protocols were used alternately, with simultaneous acquisition of frontal and lateral radiographs. LLA measurements were performed by two independent observers (n = 526). In 15 children per morphotype, a third observer performed measurements twice (n = 180). Intraclass correlation coefficients and the dose (delivered, absorbed) were calculated. 100 girls and 160 boys (mean age = 11.7 years) were investigated: 74 M1 (mean BMI, 15.7kg/m 2 ), 149 M2 (19.8 kg/m 2 ) and 40 M3 (30.2 kg/m 2 ). With microdose, inter- and intra-observer agreement was >0.90 for lengths whatever the morphotype, 0.75-0.90 (M1) and >0.90 (M2, M3) for valgus/varus and flexion/hyperextension deviations. Dose reduction reached a factor of 8.5 and 5.4 for the delivered and absorbed dose respectively. Microdose could be used for LLA measurements in children and permits a significant dose reduction. (orig.)

  9. Vitamin D mediated changes in the calcium accumulation in rat osteogenic sarcoma cells

    International Nuclear Information System (INIS)

    Kim, Y.S.; Birge, S.J.; Miller, R.; Avioli, L.V.

    1986-01-01

    Rat osteogenic sarcoma cells (ROS 17/2) have long served as a model system for studying osteoblastic cell function and regulation. To delineate the action of 1,25(OH) 2 D 3 on ROS cell function, 45 Ca accumulation in response to the vitamin was studied. Cells were grown in the presence and absence of 1,25(OH) 2 D 3 for 48 hours and then incubated for 4 min. in media containing 45 Ca. In cultures at 100% confluency, 0.25-1.0 pg/ml of 1,25 (OH) 2 D 3 stimulated 45 Ca accumulation per mg of cell proteins, while 80 pg/ml or higher dosages inhibited accumulation. In cultures at 50% confluency, doses less than 80 pg/ml were without effect while 80-120 pg/ml dosages stimulated accumulation, and as much as 1000 pg/ml had no effect. These results indicate that the ROS cell response to 1,25(OH) 2 D 3 is biphasic with low doses stimulating, higher doses inhibiting 45 Ca accumulation. Furthermore, the sensitivity of the cells to 1,25(OH) 2 D 3 increases as the cell population approaches confluence. Thus, in characterizing ROS cell function, it is important to carefully define the dose-response relationship and the cell culture density

  10. RaD-X: Complementary measurements of dose rates at aviation altitudes

    Science.gov (United States)

    Meier, Matthias M.; Matthiä, Daniel; Forkert, Tomas; Wirtz, Michael; Scheibinger, Markus; Hübel, Robert; Mertens, Christopher J.

    2016-09-01

    The RaD-X stratospheric balloon flight organized by the National Aeronautics and Space Administration was launched from Fort Sumner on 25 September 2015 and carried several instruments to measure the radiation field in the upper atmosphere at the average vertical cutoff rigidity Rc of 4.1 GV. The German Aerospace Center (Deutsches Zentrum für Luft- und Raumfahrt) in cooperation with Lufthansa German Airlines supported this campaign with an independent measuring flight at the altitudes of civil aviation on a round trip from Germany to Japan. The goal was to measure dose rates under similar space weather conditions over an area on the Northern Hemisphere opposite to the RaD-X flight. Dose rates were measured in the target areas, i.e., around vertical cutoff rigidity Rc of 4.1 GV, at two flight altitudes for about 1 h at each position with acceptable counting statistics. The analysis of the space weather situation during the flights shows that measuring data were acquired under stable and moderate space weather conditions with a virtually undisturbed magnetosphere. The measured rates of absorbed dose in silicon and ambient dose equivalent complement the data recorded during the balloon flight. The combined measurements provide a set of experimental data suitable for validating and improving numerical models for the calculation of radiation exposure at aviation altitudes.

  11. Photon and neutron doses of the personnel using moisture and density measurement devices

    Energy Technology Data Exchange (ETDEWEB)

    Carinou, E.; Papadomarkaki, E.; Tritakis, P.; Hourdakis, C.I.; Kamenopoulou, V. [Greek Atomic Energy Commission, Agia Paraskevi, Attiki, 60092 (Greece)

    2006-07-01

    The objective of this study is to present the evolution of the photon doses received by the workers who use mobile devices for measuring the moisture and the density in various materials and to estimate the neutron doses. The workers employed in more than 30 construction companies in Greece were 76 in 2004. The devices used for that purpose incorporate a {sup 137}Cs source for density measurements and an {sup 241}Am-Be source for moisture measurements of soil, asphalt or concrete. Photon and neutron measurements were performed occasionally during the on site inspections. The results of the measurements showed that the photon and neutron dose rates were not negligible. The workers were monitored for photon radiation using film badges (Kodak Type 2, Holder NRPB type) till the year 2000 and then TLD badges issued by the Greek Atomic Energy Commission (GAEC), on a monthly basis. Since the neutron dose rates measured by a rem-meter were not so high, no neutron dosemeters were issued for them. Their personal dose equivalent data for photons are kept in the National Dose Registry Information System (N.D.R.I.S.) in G.A.E.C. and were used for statistical analysis for the period from 1997 till 2004. As far as the neutrons are concerned, a Monte Carlo code was used to simulate the measuring devices and the working positions in order to calculate the neutron individual doses. (authors)

  12. Photon and neutron doses of the personnel using moisture and density measurement devices

    International Nuclear Information System (INIS)

    Carinou, E.; Papadomarkaki, E.; Tritakis, P.; Hourdakis, C.I.; Kamenopoulou, V.

    2006-01-01

    The objective of this study is to present the evolution of the photon doses received by the workers who use mobile devices for measuring the moisture and the density in various materials and to estimate the neutron doses. The workers employed in more than 30 construction companies in Greece were 76 in 2004. The devices used for that purpose incorporate a 137 Cs source for density measurements and an 241 Am-Be source for moisture measurements of soil, asphalt or concrete. Photon and neutron measurements were performed occasionally during the on site inspections. The results of the measurements showed that the photon and neutron dose rates were not negligible. The workers were monitored for photon radiation using film badges (Kodak Type 2, Holder NRPB type) till the year 2000 and then TLD badges issued by the Greek Atomic Energy Commission (GAEC), on a monthly basis. Since the neutron dose rates measured by a rem-meter were not so high, no neutron dosemeters were issued for them. Their personal dose equivalent data for photons are kept in the National Dose Registry Information System (N.D.R.I.S.) in G.A.E.C. and were used for statistical analysis for the period from 1997 till 2004. As far as the neutrons are concerned, a Monte Carlo code was used to simulate the measuring devices and the working positions in order to calculate the neutron individual doses. (authors)

  13. Measurement of MV CT dose index for Hi-ART helical tomotherapy unit

    International Nuclear Information System (INIS)

    Wang Yunlai; Liao Xiongfei

    2010-01-01

    Objective: To evaluate the patient dose from Hi-ART MV helical CT imaging in image-guided radiotherapy. Methods: Weighted CT dose index (CTDI W ) was measured with PTW TM30009 CT ion chamber in head and body phantoms, respectively,for slice thicknesses of 2, 4, 6 mm with scanned range of 5 cm and 15 cm. Dose length products (DLP) were subsequently calculated. The CTDI W and DLP were compared with XVI kV CBCT and ACQSim simulator CT for routine clinical protocols. Results: An inverse relationship between CTDI and the slice thickness was found. The dose distribution was inhomogeneous owing to the attenuation of the couch. CTDI and DLP had close relationship with the slice thickness and the scanned range. Patient dose from MVCT was lower than XVI CBCT for head, but larger for body scan. Conclusions: CTDI W can be used to assess the patient dose in MV helical CT due to its simplicity for measurement and reproducibility. Regular measurement should be performed in QA and QC program. Appropriate slice thickness and scan range should be chosen to reduce the patient dose. (authors)

  14. Effects of ionization chamber construction on dose measurements in a heterogeneity

    International Nuclear Information System (INIS)

    Mauceri, T.; Kase, K.

    1987-01-01

    Traditionally, measurements have been made in heterogeneous phantoms to determine the factors which should be applied to dose calculations, when calculating a dose to a heterogeneous medium. Almost all measurements have relied on relatively thin-walled ion chambers, with no attempt to match ion chamber wall material to the measuring medium. The recent AAPM dosimetry protocol has established that a mismatch between ion chamber wall and phantom material can have an effect on dose measurement. To investigate the affect of this mismatch of ion chamber wall material to phantom material, two parallel-plate ion chambers were constructed. One ion chamber from solid water, for measurements in a solid water phantom and the other from plastic lung material, for measurements in a plastic lung material phantom. Correction factors measured by matching ion chamber to media were compared to correction factors measured by using a thin-walled cavity ion chamber with no regard for matching wall and media for cobalt-60, 6-, 10- and 20-MV photon beams. The results demonstrated that the matching of ion chamber to measuring media can be ignored, provided that a small, approximately tissue-equivalent, thin-walled ion chamber is used for measuring the correction factors

  15. Measurement of doses to aviator pilots using thermoluminescent dosemeters

    International Nuclear Information System (INIS)

    Azorin N, J.; Cruz C, D.; Rivera M, T.

    2004-01-01

    During the development of their work, the aviator pilots are exposed at high levels of natural radiation of bottom caused mainly by the cosmic radiation of galactic origin and lot. For such reason, the Metropolitan Autonomous University (UAM) and the Union Association of Aviator Pilots (ASPA), subscribed an agreement with the purpose of to measure the doses of ionizing radiation received by the aviator pilots of diverse air companies that man different types of airships and to determine if these doses surpass the one limit of 0.11 mSv/h settled down by the IAEA for the public in general; and if therefore, these workers should be considered as personnel occupationally exposed. In this work the obtained results when measuring the absorbed dose received by Mexican civil aviator pilots during the development of their work, using thermoluminescent dosemeters of LiF:Mg,Cu,P + Ptfe of national production are presented. The obtained results during the years of 2001 and 2002 show that the monthly doses received by the pilots surpass the one it limits established for the public in general, for what they should be considered as personnel occupationally exposed. (Author)

  16. Measurement of radiotherapy CBCT dose in a phantom using different methods

    International Nuclear Information System (INIS)

    Hu, Naonori; McLean, Donald

    2014-01-01

    Cone beam computed tomography (CBCT) is used widely for the precise and accurate patient set up needed during radiation therapy, notably for hypo fractionated treatments, such as intensity modulated radiation therapy and stereotactic radiation therapy. Reported doses associated with CBCT indicate the potential to approach radiation tolerance levels for some critical organs. However while some manufacturers state the CBCT dose for each standard protocol, currently there are no standard or recognised protocols for CBCT dosimetry. This study has applied wide beam computed tomography dosimetry approaches as reported by the International Atomic Energy Agency and the American Association of Physicists in Medicine to investigate dosimetry for the Varian Trilogy linear accelerator with on-board imager v1.5. Three detection methods were used including (i) the use of both 100 mm and 300 mm pencil ionisation chambers, (ii) a 0.6 cm 3 ionisation chamber and (iii) gafchromic film. Measurements were performed using custom built 45 cm long PMMA phantoms as well as standard 15 cm long phantoms for both head and body simulation. The results showed good agreement between each other detector system (within 3 %). The measured CBCT dose for the above methods showed a large difference to the dose stated by Varian, with the measured dose being 40 % over the stated dose for the standard head protocol. This shows the importance of independently verifying the stated dose given by the vendor for standard procedures.

  17. Ionizing radiation population doses at Sao Paulo city, Brazil: open-pit gamma dose measurement

    International Nuclear Information System (INIS)

    Oliveira, Raimundo Enoch Rodrigues

    2001-01-01

    The effects of ionizing radiation to the human beings are well known for high and intermediate doses. As far as low level) radiation doses are concerned, there is no consensus. In order to get a better understanding of such effects it is necessary to assess the low doses with better accuracy. In this work, it was made an estimate of the annual ambient dose equivalent (H * (10)) to which the people are exposed in the city of Sao Paulo. Until now there are no data about it available in the literature. For the purpose of this evaluation, a map with various routes covering the largest and more representative area of the city was designed. The choice of points for data collection was made taking into account mainly the occupancy of the region. A portable gamma spectrometry system was used. It furnishes the rate of H * (10) and the measured gamma spectrum (in the range from 50 to 1670 keV) in the place of interest. The measurements were performed in a short time interval, since the gamma radiation arrives from a great extent of soil. Each measurement was done 1 m above the soil during 300 s. The rates of H * (10) varied from 33.1 to 152.3 nSv.h -1 , net values, obtained after subtraction of the cosmic rays contribution. The standard deviation was 22 n Sv.h -1 for an average for the city of Sao Paulo of 96.1(24) nSv.h -1 . In addition, average values of H * (10) rates for the city Health Divisions were calculated. Those values are not statistically equivalent and the whole set of data could not be treated as one, as the statistical Student test indicated a non homogeneity of the group of data. Hence it is necessary the accomplishment of a more detailed survey in order to verify the origin of the discrepancy. The mean value of H * (10) rate obtained for the city of Sao Paulo as converted to effective dose. in order to be compared with other places results It could be noticed that the annual average of effective dose for the city of Sao Paulo, 0.522(13) mSv, is superior to

  18. SU-F-J-89: Assessment of Delivered Dose in Understanding HCC Tumor Progression Following SBRT

    Energy Technology Data Exchange (ETDEWEB)

    McCulloch, M; Cazoulat, G; Polan, D; Schipper, M; Lawrence, T; Feng, M; Brock, K [University of Michigan, Ann Arbor, MI (United States)

    2016-06-15

    Purpose: It is well documented that the delivered dose to patients undergoing radiotherapy (RT) is often different from the planned dose due to geometric variability and uncertainties in patient positioning. Recent work suggests that accumulated dose to the GTV is a better predictor of progression compared to the minimum planned dose to the PTV. The purpose of this study is to evaluate if deviations from the planned dose can contributed to tumor progression. Methods: From 2010 to 2014 an in-house Phase II clinical trial of adaptive stereotactic body RT was completed. Of the 90 patients enrolled, 7 patients had a local recurrence defined on contrast enhanced CT or MR imaging 3–21 months after completion of RT. Retrospective dose accumulation was performed using a biomechanical model-based deformable image registration algorithm (DIR) to accumulate the dose based on the kV CBCT acquired prior to each fraction for soft tissue alignment of the patient. The DIR algorithm was previously validated for geometric accuracy in the liver (target registration error = 2.0 mm) and dose accumulation in a homogeneous image, similar to a liver CBCT (gamma index = 91%). Following dose accumulation, the minimum dose to 0.5 cc of the GTV was compared between the planned and accumulated dose. Work is ongoing to evaluate the tumor control probability based on the planned and accumulated dose. Results: DIR and dose accumulation was performed on all fractions for 6 patients with local recurrence. The difference in minimum dose to 0.5 cc of the GTV ranged from −0.3–2.3 Gy over 3–5 fractions. One patient had a potentially significant difference in minimum dose of 2.3 Gy. Conclusion: Dose accumulation can reveal tumor underdosage, improving our ability to understand recurrence and tumor progression patterns, and could aid in adaptive re-planning during therapy to correct for this. This work was supported in part by NIH P01CA059827.

  19. In-vivo (entrance) dose measurements in external beam radiotherapy with aqueous FBX dosimetry system

    International Nuclear Information System (INIS)

    Semwal, M.K.; Thakur, P.K.; Bansal, A.K.; Vidyasagar, P.B.

    2005-01-01

    FBX aqueous chemical dosimetry system has been found useful in radiotherapy owing to its low dose measuring capability. In the present work, entrance dose measurements in external beam radiotherapy on a telecobalt machine were carried out with the system on 100 patients. Treatments involving simple beam arrangement of open parallel-opposed beams in cranial and pelvic irradiations were selected for this study. In place of a spectrophotometer, a simple and inexpensive colorimeter was used for absorbance measurements. The purpose was to assess the efficacy of the FBX system for in-vivo dose measurements. The results obtained show that the average discrepancy between the measured and expected dose for both categories of patients was 0.2% (standard deviation 3.2%) with a maximum of +1 0.3%. There were 5.5% cases showing more than ± 5% discrepancy. Comparison of the results obtained with published work on entrance dose measurements, with diode detectors, shows that the inexpensive FBX system can be used for in-vivo (entrance) dose measurements for simple beam arrangements in radiotherapy and can thus serve as a useful QA tool. (author)

  20. Quantitative analysis of biological responses to low dose-rate γ-radiation, including dose, irradiation time, and dose-rate

    International Nuclear Information System (INIS)

    Magae, J.; Furukawa, C.; Kawakami, Y.; Hoshi, Y.; Ogata, H.

    2003-01-01

    Full text: Because biological responses to radiation are complex processes dependent on irradiation time as well as total dose, it is necessary to include dose, dose-rate and irradiation time simultaneously to predict the risk of low dose-rate irradiation. In this study, we analyzed quantitative relationship among dose, irradiation time and dose-rate, using chromosomal breakage and proliferation inhibition of human cells. For evaluation of chromosome breakage we assessed micronuclei induced by radiation. U2OS cells, a human osteosarcoma cell line, were exposed to gamma-ray in irradiation room bearing 50,000 Ci 60 Co. After the irradiation, they were cultured for 24 h in the presence of cytochalasin B to block cytokinesis, cytoplasm and nucleus were stained with DAPI and propidium iodide, and the number of binuclear cells bearing micronuclei was determined by fluorescent microscopy. For proliferation inhibition, cells were cultured for 48 h after the irradiation and [3H] thymidine was pulsed for 4 h before harvesting. Dose-rate in the irradiation room was measured with photoluminescence dosimeter. While irradiation time less than 24 h did not affect dose-response curves for both biological responses, they were remarkably attenuated as exposure time increased to more than 7 days. These biological responses were dependent on dose-rate rather than dose when cells were irradiated for 30 days. Moreover, percentage of micronucleus-forming cells cultured continuously for more than 60 days at the constant dose-rate, was gradually decreased in spite of the total dose accumulation. These results suggest that biological responses at low dose-rate, are remarkably affected by exposure time, that they are dependent on dose-rate rather than total dose in the case of long-term irradiation, and that cells are getting resistant to radiation after the continuous irradiation for 2 months. It is necessary to include effect of irradiation time and dose-rate sufficiently to evaluate risk

  1. Dose measurement of ion implanted silicon by RBS technique

    International Nuclear Information System (INIS)

    Kamawanna, Teerasak; Intarasiri, Saweat; Prapunsri, Chowunchun; Thongleurm, Chome; Maleepatra, Saenee; Singkarat, Somsorn

    2003-10-01

    Surface modification can be achieved by ion implantation. This study used a 1 mm thick silicon wafer as a target which was implanted with Ar+ at 80 keV. The degree of the modification depends on both the ion energy and the implanted dose. The distribution of argon in the silicon substrate and the absolute implanted dose can be measured by using Rutherford Backscattering Spectrometry (RBS). These investigations utilized a 1.7 MV Tandetron accelerator system at Chiang Mai University. The dose determination by a direct calculation is in agreement with the simulation by the SIMNRA code

  2. Using RADFET for the real-time measurement of gamma radiation dose rate

    Science.gov (United States)

    Andjelković, Marko S.; Ristić, Goran S.; Jakšić, Aleksandar B.

    2015-02-01

    RADFETs (RADiation sensitive Field Effect Transistors) are integrating ionizing radiation dosimeters operating on the principle of conversion of radiation-induced threshold voltage shift into absorbed dose. However, one of the major drawbacks of RADFETs is the inability to provide the information on the dose rate in real-time using the conventional absorbed dose measurement technique. The real-time monitoring of dose rate and absorbed dose can be achieved with the current mode dosimeters such as PN and PIN diodes/photodiodes, but these dosimeters have some limitations as absorbed dose meters and hence they are often not a suitable replacement for RADFETs. In that sense, this paper investigates the possibility of using the RADFET as a real-time dose rate meter so that it could be applied for simultaneous online measurement of the dose rate and absorbed dose. A RADFET sample, manufactured by Tyndall National Institute, Cork, Ireland, was tested as a dose rate meter under gamma irradiation from a Co-60 source. The RADFET was configured as a PN junction, such that the drain, gate and source terminals were grounded, while the radiation-induced current was measured at the bulk terminal, whereby the bulk was successively biased with 0 , 10 , 20  and 30 V. In zero-bias mode the radiation-induced current was unstable, but in the biased mode the current response was stable for the investigated dose rates from 0.65  to 32.1 Gy h-1 and up to the total absorbed dose of 25 Gy. The current increased with the dose rate in accordance with the power law, whereas the sensitivity of the current read-out was linear with respect to the applied bias voltage. Comparison with previously analyzed PIN photodiodes has shown that the investigated RADFET is competitive with PIN photodiodes as a gamma radiation dose rate meter and therefore has the potential to be employed for the real-time monitoring of the dose rate and absorbed dose.

  3. Using RADFET for the real-time measurement of gamma radiation dose rate

    International Nuclear Information System (INIS)

    Andjelković, Marko S; Ristić, Goran S; Jakšić, Aleksandar B

    2015-01-01

    RADFETs (RADiation sensitive Field Effect Transistors) are integrating ionizing radiation dosimeters operating on the principle of conversion of radiation-induced threshold voltage shift into absorbed dose. However, one of the major drawbacks of RADFETs is the inability to provide the information on the dose rate in real-time using the conventional absorbed dose measurement technique. The real-time monitoring of dose rate and absorbed dose can be achieved with the current mode dosimeters such as PN and PIN diodes/photodiodes, but these dosimeters have some limitations as absorbed dose meters and hence they are often not a suitable replacement for RADFETs. In that sense, this paper investigates the possibility of using the RADFET as a real-time dose rate meter so that it could be applied for simultaneous online measurement of the dose rate and absorbed dose. A RADFET sample, manufactured by Tyndall National Institute, Cork, Ireland, was tested as a dose rate meter under gamma irradiation from a Co-60 source. The RADFET was configured as a PN junction, such that the drain, gate and source terminals were grounded, while the radiation-induced current was measured at the bulk terminal, whereby the bulk was successively biased with 0 , 10 , 20  and 30 V. In zero-bias mode the radiation-induced current was unstable, but in the biased mode the current response was stable for the investigated dose rates from 0.65  to 32.1 Gy h −1 and up to the total absorbed dose of 25 Gy. The current increased with the dose rate in accordance with the power law, whereas the sensitivity of the current read-out was linear with respect to the applied bias voltage. Comparison with previously analyzed PIN photodiodes has shown that the investigated RADFET is competitive with PIN photodiodes as a gamma radiation dose rate meter and therefore has the potential to be employed for the real-time monitoring of the dose rate and absorbed dose. (paper)

  4. Dose measurements in laboratory of Physics department, University of Khartoum

    International Nuclear Information System (INIS)

    Hamid, Maria Mohammed

    1999-05-01

    Personal monitoring in University of Khartoum is being conducted using thermoluminescent dosimetry. The purpose of the study is to measure the dose of radiation in laboratory of Physics in physics department. TL phosphors LiF: Mg, Ti (card) and LiF Mg, Cu, P (GR-200) and mini-rad dosimeter are used to measure the dose in laboratory. The total dose for students form the laboratory bu using card, GR-200 and mini-rad dosimeter was found to be 2.2μ sv/year. 2.5 μ sv/year and 2.6 μ sv respectively, and for the teacher about 4.0 μ sv/year, 5.8 μ sv/year and 13.6 μ sv/year respectively, and for the dose near junk room about 3.9 μ sv/year, 2.9 μ sv/year and 2.8 μ sv/year by using card, GR-200 and mini-rad dosimeter respectively. There is just a background radiation in the main library and the applied nuclear.(Author)

  5. Is it sensible to “deform” dose? 3D experimental validation of dose-warping

    International Nuclear Information System (INIS)

    Yeo, U. J.; Taylor, M. L.; Supple, J. R.; Smith, R. L.; Dunn, L.; Kron, T.; Franich, R. D.

    2012-01-01

    Purpose: Strategies for dose accumulation in deforming anatomy are of interest in radiotherapy. Algorithms exist for the deformation of dose based on patient image sets, though these are sometimes contentious because not all such image calculations are constrained by physical laws. While tumor and organ motion has been a key area of study for a considerable amount of time, deformation is of increasing interest. In this work, we demonstrate a full 3D experimental validation of results from a range of dose deformation algorithms available in the public domain. Methods: We recently developed the first tissue-equivalent, full 3D deformable dosimetric phantom—“DEFGEL.” To assess the accuracy of dose-warping based on deformable image registration (DIR), we have measured doses in undeformed and deformed states of the DEFGEL dosimeter and compared these to planned doses and warped doses. In this way we have directly evaluated the accuracy of dose-warping calculations for 11 different algorithms. We have done this for a range of stereotactic irradiation schemes and types and magnitudes of deformation. Results: The original Horn and Schunck algorithm is shown to be the best performing of the 11 algorithms trialled. Comparing measured and dose-warped calculations for this method, it is found that for a 10 × 10 mm 2 square field, γ 3%/3mm = 99.9%; for a 20 × 20 mm 2 cross-shaped field, γ 3%/3mm = 99.1%; and for a multiple dynamic arc (0.413 cm 3 PTV) treatment adapted from a patient treatment plan, γ 3%/3mm = 95%. In each case, the agreement is comparable to—but consistently ∼1% less than—comparison between measured and calculated (planned) dose distributions in the absence of deformation. The magnitude of the deformation, as measured by the largest displacement experienced by any voxel in the volume, has the greatest influence on the accuracy of the warped dose distribution. Considering the square field case, the smallest deformation (∼9 mm) yields

  6. Exact comparison of dose rate measurements and calculation of TN12/2 packages

    International Nuclear Information System (INIS)

    Taniuchi, H.; Matsuda, F.

    1998-01-01

    Both of dose rate measurements of TN 12/2 package and calculations by Monte Carlo code MORSE in SCALE code system and MCNP were performed to evaluate the difference between the measurement and the calculation and finding out the cause of the difference. The calculated gamma-ray dose rates agreed well with measured ones, but calculated neutron dose rates overestimated more than a factor of 1.7. When considering the cause of the difference and applying the modification into the neutron calculation, the calculated neutron dose rates become to agree well, and the factor decreased to around 1.3. (authors)

  7. Entrance surface dose measurements in pediatric radiological examinations

    International Nuclear Information System (INIS)

    Ribeiro, L.A.; Yoshimura, E.M.

    2008-01-01

    A survey of pediatric radiological examinations was carried out in a reference pediatric hospital of the city of Sao Paulo, in order to investigate the doses to children undergoing conventional X-ray examinations. The results showed that the majority of pediatric patients are below 4 years, and that about 80% of the examinations correspond to chest projections. Doses to typical radiological examinations were measured in vivo with thermoluminescent dosimeters (LiF: Mg, Ti and LiF: Mg, Cu, P) attached to the skin of the children to determine entrance surface dose (ESD). Also homogeneous phantoms were used to obtain ESD to younger children, because the technique uses a so small kVp that the dosimeters would produce an artifact image in the patient radiograph. Four kinds of pediatric examinations were investigated: three conventional examinations (chest, skull and abdomen) and a fluoroscopic procedure (barium swallow). Relevant information about kVp and mAs values used in the examinations was collected, and we discuss how these parameters can affect the ESD. The ESD values measured in this work are compared to reference levels published by the European Commission for pediatric patients. The results obtained (third-quartile of the ESD distribution) for chest AP examinations in three age groups were: 0.056 mGy (2-4 years old); 0.068 mGy (5-9 years old); 0.069 mGy (10-15 years old). All of them are below the European reference level (0.100 mGy). ESD values measured to the older age group in skull and abdomen AP radiographs (mean values 3.44 and 1.20 mGy, respectively) are above the European reference levels (1.5 mGy to skull and 1.0 mGy to abdomen). ESD values measured in the barium swallow examination reached 10 mGy in skin regions corresponding to thyroid and esophagus. It was noticed during this survey that some technicians use, improperly, X-ray fluoroscopy in conventional examinations to help them in positioning the patient. The results presented here are a

  8. Measurements of the Cosmic Rays Dose at Different Altitudes of Iran

    International Nuclear Information System (INIS)

    Faghihi, R.; Mehdizadeh, S.; Jafarizadeh, M.; Sina, S.; Zehtabian, M.; Taheri, M.

    2012-01-01

    The amount of cosmic rays varies widely with the altitude, latitude and longitude in each region. In this study, the radiation doses due to the cosmic rays were estimated in two steps: in the first step, the neutron and gamma components of the radiation dose were measured for a roundtrip flight on 3 flight routes (Shiraz-Asaluye, Asaluye-Rasht and Shiraz-Mashhad) using a gamma-tracer photon detector and a Thyac 190 N, neutron detector. The minimum values of the measured gamma and neutron doses of 0.15 and 0.04μSv were measured on the Asaluyeh-Shiraz route at the lowest altitude of 19000 ft, while for Rasht-Asaluyeh route at an altitude of 35000 ft those values were found to be 2.52 and 1.09 mSv, respectively. In the second step, a number of air crew members were equipped with thermoluminescence dosimeters (TLD cards) for evaluating the gamma dose and polycarbonate dosimeters (SSNTD) for assessing the neutron dose for one year. The measured value of the annual effective dose received by the crew ranged between 0.5 mSv/y and 1.16 mSv/y, with an average of 0.9 mSv/y for the gamma component and between 0.37 mSv/y and 0.77 mSv/y with an average of 0.61 mSv/y for the neutron component. The results of this investigation are comparable with the investigations that have been conducted in other countries. For instance in UK, the reported annual effective dose of air crew is about 2 mSv, and in Canada, it is estimated to be between 1 to 5 mSv, depending on the flight situations (such as the latitude and longitude of the cities, the flight altitude, etc).

  9. Assessments of conversion coefficients between equivalent dose and accumulated activity using pre-dose scanning images of patients subjected to radioiodine treatment and the Fax/Egs4 computational model

    International Nuclear Information System (INIS)

    Lopes Filho, Ferdinand de J.; Vieira, Jose W.; Andrade Lima, Fernando R. de

    2008-01-01

    The radioiodine is a technique for treatment of thyroid cancer. In this technique, the patients are submitted to the incorporation of the radioactive substance sodium iodide (Na 131 I), which reacts with physiologically metastasis, thyroid tissue remains of and other organs and tissues of the human body. The locations of these reactions are known as areas of highest concentration, hipercaptured areas, hiperconcentrator areas, 'hot areas' or organ-sources and are viewed through images of nuclear medicine scan known as pre-dose (front and rear). To obtain these images, the patient receives, orally, a quantity of 131 I with low activity (± 74 MBq) and is positioned in the chamber of flicker. According to the attendance of hot areas shown in the images, the doctor determines the nuclear activity to be administered in treatment. This analysis is purely qualitative. In this study, the scanning images of pre-dose were adjusted to the dimensions of FAX voxel phantom, and the hot areas correspond to internal sources of the proposed model. Algorithms were developed to generate particles (photons and electrons) in these regions of the FAX. To estimate the coefficients of conversions between equivalent dose and accumulated activity in major radiosensitive organs, FAX and algorithms source were coupled to the Monte Carlo EGS4 code (Electron Gamma Shower, version 4). With these factors is possible to estimate the equivalent doses in the radiosensitive organs and tissues of patients as long as is know the activity administered and the half-life of organic sources. (author)

  10. Study of the Radiochromic Film for High Dose Measurement in Radiation Processing

    Directory of Open Access Journals (Sweden)

    CHEN Yi-zhen

    2016-02-01

    Full Text Available To establish the radiochromic film dosimeter for high dose level measurement during radiation processing, By corresponding formula and its preparation process research, batches of radiochromic film dosimeters were prepared using nylon as substrate and pararosaniline cyanide as dye. In Co-60 gamma reference radiation field, dosimetry response performance of radiochromic film was studied and results showed that the repeatability was good to 1.0%. The response curves demonstrated good linearity in the dose range of 5-210 kGy, and the signal of radiochromic film dosimeters after irradiation under the condition of low temperature storage within 2 weeks was stable. In addition, the radiochromic film dosimeters were not found to have noticeable dose rate dependence in the range of this experiment. In the linear dose range, radiochromic film dosimeter measures the absorbed dose, with extended uncertainty 4.2% (k=2 for Co-60 gamma rays. The film was suitable as dosimeters for the parameters measurement of the electron beam on the accelerator.

  11. Estimate of the dose received in crystalline lens by pediatric interventional cardiologists

    International Nuclear Information System (INIS)

    Koren, C.; Alejo, L.; Serrada, A.

    2014-08-01

    The objective of this work is to estimate the maximum dose accumulated during one year in the crystalline lens of the pediatric interventional cardiologists that work in the Hospital Universitario La Paz. Optically Stimulated Luminescence Dosimeters (OSLDs) were used for to carry out this estimation, placed in the eyes of an anthropomorphic mannequin whose position in the room simulates the more habitual conditions of the clinical practice. Previously to the simulation, different tests to validate the used dosimetric system were realized, including those related with the stability, reproducibility and lector linearity, as well as the angular and energy dependence of the OSLDs. During the simulation the mannequin eyes were irradiated and were measured with OSLDs the rate of superficial equivalent dose in crystalline lens for the different qualities of beam habitually used, as much in fluoroscopy as in acquisition. With the obtained data during three years, corresponding to the fluoroscopy times and the acquisitions number of the interventional procedures carried out; as much therapeutic as diagnostic, and rate by measuring of obtained dose, has been considered the superficial equivalent dose and the equivalent dose at 3 mm deep accumulated in the crystalline lens of the pediatric interventional cardiologist with more work load of the Hospital, during the years 2011 and 2012. None of the obtained maximum values exceed the new dose annual limit in crystalline lens of 20 mSv, recommended by ICRP in April of 2011. (author)

  12. Measurement of gamma radiation doses at the RA reactor by thermoluminescent dosemeters

    International Nuclear Information System (INIS)

    Prokic, M.

    1974-01-01

    This paper presents the procedures and gamma radiation doses measured at the exit from the horizontal experimental channel HK-5, vertical experimental channel VK-5 and in the thermal column of the RA reactor in Vinca. Measurement of gamma radiation dose in the mixed intense gamma and neutron radiation field was done by two types of thermoluminescent dosemeters, LiF (TLD-700) and CaF 2 (TLD-08). Gamma dose in the VK-5 was measured in the air and on the bottle filled with tissue-equivalent solution. Increase of the dose on the surface of the bottle was 2.3 compared to the gamma dose value in the air. Correction for the influence of neutrons having different energies was done by using the known sensitivity values of both TL dosemeter types for thermal, intermediate and fast neutrons. Results showed that the TLD-700 dosemeter contains 5 time more Li-6 isotopes (0.035%) than the declared value causing increased neutron sensitivity of this dosemeter. This paper includes numerical sensitivity data for neutrons of different energies for both types of TL dosemeters. Neutron sensitivity values for TLD-700 are related to LiF with 0.035% of Li-6 isotope. Result of measurement have also shown that the CaF 2 :Mn (TLD-08) thermoluminescent dosemeter is more suitable for gamma radiation dose measurements in mixed n-gamma fields with intensive neutron fluxes due to lower neutron sensitivity compared to TLD-700 [sr

  13. In vivo dose measurement using TLDs and MOSFET dosimeters for cardiac radiosurgery.

    Science.gov (United States)

    Gardner, Edward A; Sumanaweera, Thilaka S; Blanck, Oliver; Iwamura, Alyson K; Steel, James P; Dieterich, Sonja; Maguire, Patrick

    2012-05-10

    In vivo measurements were made of the dose delivered to animal models in an effort to develop a method for treating cardiac arrhythmia using radiation. This treatment would replace RF energy (currently used to create cardiac scar) with ionizing radiation. In the current study, the pulmonary vein ostia of animal models were irradiated with 6 MV X-rays in order to produce a scar that would block aberrant signals characteristic of atrial fibrillation. The CyberKnife radiosurgery system was used to deliver planned treatments of 20-35 Gy in a single fraction to four animals. The Synchrony system was used to track respiratory motion of the heart, while the contractile motion of the heart was untracked. The dose was measured on the epicardial surface near the right pulmonary vein and on the esophagus using surgically implanted TLD dosimeters, or in the coronary sinus using a MOSFET dosimeter placed using a catheter. The doses measured on the epicardium with TLDs averaged 5% less than predicted for those locations, while doses measured in the coronary sinus with the MOSFET sensor nearest the target averaged 6% less than the predicted dose. The measurements on the esophagus averaged 25% less than predicted. These results provide an indication of the accuracy with which the treatment planning methods accounted for the motion of the target, with its respiratory and cardiac components. This is the first report on the accuracy of CyberKnife dose delivery to cardiac targets.

  14. Skin dose measurements using MOSFET and TLD for head and neck patients treated with tomotherapy

    International Nuclear Information System (INIS)

    Kinhikar, Rajesh A.; Murthy, Vedang; Goel, Vineeta; Tambe, Chandrashekar M.; Dhote, Dipak S.; Deshpande, Deepak D.

    2009-01-01

    The purpose of this work was to estimate skin dose for the patients treated with tomotherapy using metal oxide semiconductor field-effect transistors (MOSFETs) and thermoluminescent dosimeters (TLDs). In vivo measurements were performed for two head and neck patients treated with tomotherapy and compared to TLD measurements. The measurements were subsequently carried out for five days to estimate the inter-fraction deviations in MOSFET measurements. The variation between skin dose measured with MOSFET and TLD for first patient was 2.2%. Similarly, the variation of 2.3% was observed between skin dose measured with MOSFET and TLD for second patient. The tomotherapy treatment planning system overestimated the skin dose as much as by 10-12% when compared to both MOSFET and TLD. However, the MOSFET measured patient skin doses also had good reproducibility, with inter-fraction deviations ranging from 1% to 1.4%. MOSFETs may be used as a viable dosimeter for measuring skin dose in areas where the treatment planning system may not be accurate.

  15. Skin dose measurements using MOSFET and TLD for head and neck patients treated with tomotherapy.

    Science.gov (United States)

    Kinhikar, Rajesh A; Murthy, Vedang; Goel, Vineeta; Tambe, Chandrashekar M; Dhote, Dipak S; Deshpande, Deepak D

    2009-09-01

    The purpose of this work was to estimate skin dose for the patients treated with tomotherapy using metal oxide semiconductor field-effect transistors (MOSFETs) and thermoluminescent dosimeters (TLDs). In vivo measurements were performed for two head and neck patients treated with tomotherapy and compared to TLD measurements. The measurements were subsequently carried out for five days to estimate the inter-fraction deviations in MOSFET measurements. The variation between skin dose measured with MOSFET and TLD for first patient was 2.2%. Similarly, the variation of 2.3% was observed between skin dose measured with MOSFET and TLD for second patient. The tomotherapy treatment planning system overestimated the skin dose as much as by 10-12% when compared to both MOSFET and TLD. However, the MOSFET measured patient skin doses also had good reproducibility, with inter-fraction deviations ranging from 1% to 1.4%. MOSFETs may be used as a viable dosimeter for measuring skin dose in areas where the treatment planning system may not be accurate.

  16. Minimizing and measuring lens dose when giving cranial irradiation

    International Nuclear Information System (INIS)

    Woo, S.Y.; Donaldson, S.S.; Heck, R.J.; Nielson, K.L.; Shostak, C.

    1989-01-01

    Three different techniques of administering cranial irradiation were used to determine the dose to the lens as measured in the Rando phantom. The techniques employed were as follows: (1) the central axis of the radiation beam was placed at the thickest portion of the cranium; (2) the central axis of the radiation beam was placed at the lateral orbital rim (bon canthus); (3) the central axis of the radiation beam was placed at the thickest portion of the cranium but with the beam angled 5deg posteriorly away from the eye. Thermal luminescent dosimeters (TLD) were placed in a phantom, at a point determined from a life-sized anatomical section of the plane through the midsection of the eye, to be at the location of the posterior capsule of the lens. In addition, TLDs were placed on the outer surface of the phantom head, directly lateral to the location determined to be where the lens would lie. With equally weighted lateral opposed beams, delivering a midplane dose of 200cGy, the TLDs at the point of the lens measured 21, 9.9 and 10.6% of the midplane doses from the three techniques respectively. TLDs placed directly lateral to the lens on the surface of the phantom head gave an approximation of the lens dose, particularly when techniques 2 and 3 were used. Isodose curve generated by a General Electric treatment planning computer gave lens doses similar to those of the phantom data for each of the three different radiotherapy techniques. Cranial irradiation should be carried out by either technique 2 or technique 3 to minimize radiation dose to the lens. (author). 11 refs.; 2 figs.; 3 tabs

  17. An oscillating microbalance for meteorological measurements of ice and volcanic ash accumulation from a weather balloon platform

    Science.gov (United States)

    Airey, Martin; Harrison, Giles; Nicoll, Keri; Williams, Paul; Marlton, Graeme

    2017-04-01

    A new, low cost, instrument has been developed for meteorological measurements of the accumulation of ice and volcanic ash that can be readily deployed using commercial radiosondes and weather balloons. It is based on principles used by [1], an instrument originally developed to measure supercooled liquid water profiles in clouds. This new instrument introduces numerous improvements in terms of reduced complexity and cost. It uses the oscillating microbalance principle, whereby a wire vibrating at its natural frequency is subjected to increased loading of the property to be measured. The increase in mass modifies the wire properties such that its natural frequency of oscillation changes. By measuring this frequency, the increase in mass can be inferred and transmitted to a ground base station through the radiosonde's UHF antenna via the PANDORA interface [2], which has been previously developed to provide power and connection to the radiosonde telemetry. The device consists of a simple circuit board controlled by an ATMEGA microcontroller. For calibration, the controller is capable of driving the wire at specified frequencies via excitation by a piezo sounder upon which the wire is mounted. The same piezo sounder is also used during active operation to measure the frequency of the wire in its non-driven state in order to infer the mass change on the wire. A phase-locked loop implemented on the board identifies when resonance occurs and the measured frequency is stable, prompting the microcontroller to send the measurement through the data interface. The device may be used for any application that requires the measurement of incremental mass variation e.g. ice accumulation, frosting, or particle accumulation such as dust and volcanic ash. For the solid particle accumulation, a low temperature, high-tack, adhesive may be applied to the wire prior to deployment to collect the material. In addition, the same instrument may be used for ground-based applications, such as

  18. Sources of variability in OSL dose measurements using single grains of quartz

    International Nuclear Information System (INIS)

    Thomsen, K.J.; Murray, A.S.; Boetter-Jensen, L.

    2005-01-01

    In luminescence-based measurements of dose distributions in unheated mineral samples, the observed spread in dose values is usually attributed to four main factors: fluctuations in the number of photons counted, incomplete zeroing of any prior trapped charge (including signals arising from thermal transfer), heterogeneity in dosimetry, and instrument reproducibility. For correct interpretation of measured dose distributions in retrospective dosimetry, it is important to understand the relative importance of these components, and to establish whether other factors also contribute to the observed spread. In this preliminary study, dose distributions have been studied using single grains of heated and laboratory irradiated quartz. By heating the sample, the contribution from incomplete zeroing was excluded and at the same time the sample was sensitised. The laboratory gamma irradiation was designed to deliver a uniform dose to the sample. Thus it was anticipated that statistical fluctuations in the number of photons counted and instrument reproducibility, both quantifiable entities, should be able to account for all the observed variance in the measured dose distributions. We examine this assumption in detail, and discuss the origins and importance of the residual variance in our data

  19. SU-E-T-196: Comparative Analysis of Surface Dose Measurements Using MOSFET Detector and Dose Predicted by Eclipse - AAA with Varying Dose Calculation Grid Size

    Energy Technology Data Exchange (ETDEWEB)

    Badkul, R; Nejaiman, S; Pokhrel, D; Jiang, H; Kumar, P [University of Kansas Medical Center, Kansas City, KS (United States)

    2015-06-15

    Purpose: Skin dose can be the limiting factor and fairly common reason to interrupt the treatment, especially for treating head-and-neck with Intensity-modulated-radiation-therapy(IMRT) or Volumetrically-modulated - arc-therapy (VMAT) and breast with tangentially-directed-beams. Aim of this study was to investigate accuracy of near-surface dose predicted by Eclipse treatment-planning-system (TPS) using Anisotropic-Analytic Algorithm (AAA)with varying calculation grid-size and comparing with metal-oxide-semiconductor-field-effect-transistors(MOSFETs)measurements for a range of clinical-conditions (open-field,dynamic-wedge, physical-wedge, IMRT,VMAT). Methods: QUASAR™-Body-Phantom was used in this study with oval curved-surfaces to mimic breast, chest wall and head-and-neck sites.A CT-scan was obtained with five radio-opaque markers(ROM) placed on the surface of phantom to mimic the range of incident angles for measurements and dose prediction using 2mm slice thickness.At each ROM, small structure(1mmx2mm) were contoured to obtain mean-doses from TPS.Calculations were performed for open-field,dynamic-wedge,physical-wedge,IMRT and VMAT using Varian-21EX,6&15MV photons using twogrid-sizes:2.5mm and 1mm.Calibration checks were performed to ensure that MOSFETs response were within ±5%.Surface-doses were measured at five locations and compared with TPS calculations. Results: For 6MV: 2.5mm grid-size,mean calculated doses(MCD)were higher by 10%(±7.6),10%(±7.6),20%(±8.5),40%(±7.5),30%(±6.9) and for 1mm grid-size MCD were higher by 0%(±5.7),0%(±4.2),0%(±5.5),1.2%(±5.0),1.1% (±7.8) for open-field,dynamic-wedge,physical-wedge,IMRT,VMAT respectively.For 15MV: 2.5mm grid-size,MCD were higher by 30%(±14.6),30%(±14.6),30%(±14.0),40%(±11.0),30%(±3.5)and for 1mm grid-size MCD were higher by 10% (±10.6), 10%(±9.8),10%(±8.0),30%(±7.8),10%(±3.8) for open-field, dynamic-wedge, physical-wedge, IMRT, VMAT respectively.For 6MV, 86% and 56% of all measured values

  20. Conversion of ionization measurements to radiation absorbed dose in non-water density material

    International Nuclear Information System (INIS)

    El-Khatib, E.; Connors, S.

    1992-01-01

    In bone-equivalent materials two different calculations of absorbed dose are possible: the absorbed dose to soft tissue plastic (polystyrene) within bone-equivalent material and the dose to the bone-equivalent material itself. Both can be calculated from ionization measurements in phantoms. These two calculations result in significantly different doses in a heterogeneous phantom composed of polystyrene and aluminium (a bone substitute). The dose to a thin slab of polystyrene in aluminium is much higher than the dose to the aluminium itself at the same depth in the aluminium. Monte Carlo calculations confirm that the calculation of dose to polystyrene in aluminium can be accurately carried out using existing dosimetry protocols. However, the conversion of ionization measurements to absorbed dose to high atomic number materials cannot be accurately carried out with existing protocols and appropriate conversion factors need to be determined. (author)

  1. Analysis of liquid medication dose errors made by patients and caregivers using alternative measuring devices.

    Science.gov (United States)

    Ryu, Gyeong Suk; Lee, Yu Jeung

    2012-01-01

    Patients use several types of devices to measure liquid medication. Using a criterion ranging from a 10% to 40% variation from a target 5 mL for a teaspoon dose, previous studies have found that a considerable proportion of patients or caregivers make errors when dosing liquid medication with measuring devices. To determine the rate and magnitude of liquid medication dose errors that occur with patient/caregiver use of various measuring devices in a community pharmacy. Liquid medication measurements by patients or caregivers were observed in a convenience sample of community pharmacy patrons in Korea during a 2-week period in March 2011. Participants included all patients or caregivers (N = 300) who came to the pharmacy to buy over-the-counter liquid medication or to have a liquid medication prescription filled during the study period. The participants were instructed by an investigator who was also a pharmacist to select their preferred measuring devices from 6 alternatives (etched-calibration dosing cup, printed-calibration dosing cup, dosing spoon, syringe, dispensing bottle, or spoon with a bottle adapter) and measure a 5 mL dose of Coben (chlorpheniramine maleate/phenylephrine HCl, Daewoo Pharm. Co., Ltd) syrup using the device of their choice. The investigator used an ISOLAB graduated cylinder (Germany, blue grad, 10 mL) to measure the amount of syrup dispensed by the study participants. Participant characteristics were recorded including gender, age, education level, and relationship to the person for whom the medication was intended. Of the 300 participants, 257 (85.7%) were female; 286 (95.3%) had at least a high school education; and 282 (94.0%) were caregivers (parent or grandparent) for the patient. The mean (SD) measured dose was 4.949 (0.378) mL for the 300 participants. In analysis of variance of the 6 measuring devices, the greatest difference from the 5 mL target was a mean 5.552 mL for 17 subjects who used the regular (etched) dosing cup and 4

  2. Computed tomography dose and variability of airway dimension measurements: how low can we go?

    International Nuclear Information System (INIS)

    Jong, Pim A. de; Long, Frederick R.; Nakano, Yasutaka

    2006-01-01

    Quantitative CT shows promise as an outcome measure for cystic fibrosis (CF) lung disease in infancy, but must be accomplished at a dose as low as reasonably achievable. To determine the feasibility of ultra-low-dose CT for quantitative measurements of airway dimensions. Two juvenile pigs were anesthetized and their lungs scanned at 25 cm H 2 O face-mask pressure in apnoea using beam currents of 5, 10, 20, 40 and 100 mAs. The lumen diameters and wall thicknesses of matched airways (n=22) at each dose were measured by two observers using validated software. Measurement variability at each dose was compared to that at 100 mAs (reference dose) for large and small airways (lumen diameter <2.5 mm). Lowering CT dose (mAs) affected measurement variability for lumen diameter of small and large airways (P<0.001) and for wall thickness of small (P<0.001), but not large (P=0.63), airways. To obtain the same measurement variability at 5 mAs as at 100 mAs, four to six small airways or one to three large airways have to be measured and averaged. Quantitative airway measurements are feasible on images obtained at as low as 5 mAs, but more airways need to be measured to compensate for greater measurement variability. (orig.)

  3. Radiotherapy of tumors under respiratory motion. Estimation of the motional velocity field and dose accumulation based on 4D image data

    International Nuclear Information System (INIS)

    Werner, Rene

    2013-01-01

    Respiratory motion represents a major challenge in radiation therapy in general, and especially for the therapy of lung tumors. In recent years and due to the introduction of modern techniques to 'acquire temporally resolved computed tomography images (4D CT images), different approaches have been developed to explicitly account for breathing motion during treatment. An integral component of such approaches is the concept of motion field estimation, which aims at a mathematical description and the computation of the motion sequences represented by the patient's images. As part of a 4D dose calculation/dose accumulation, the resulting vector fields are applied for assessing and accounting for breathing-induced effects on the dose distribution to be delivered. The reliability of related 4D treatment planning concepts is therefore directly tailored to the precision of the underlying motion field estimation process. Taking this into account, the thesis aims at developing optimized methods for the estimation of motion fields using 4D CT images and applying the resulting methods for the analysis of breathing induced dosimetric effects in radiation therapy. The thesis is subdivided into three parts that thematically build upon each other. The first part of the thesis is about the implementation, evaluation and optimization of methods for motion field estimation with the goal of precisely assessing respiratory motion of anatomical and pathological structures represented in a patient's 4D er image sequence; this step is the basis of subsequent developments and analysis parts. Especially non-linear registration techniques prove to be well suited to this purpose. After being optimized for the particular problem at hand, it is shown as part of an extensive multi-criteria evaluation study and additionally taking into account publicly accessible evaluation platforms that such methods allow estimating motion fields with subvoxel accuracy - which means that the developed methods

  4. SU-G-IeP3-02: Characteristics of In-Vivo MOSFET Dosimeters for Diagnostic X-Ray Low-Dose Measurements

    Energy Technology Data Exchange (ETDEWEB)

    Li, S; Ali, S; Harper, K; Liang, Q; Serratore, D [Temple University Hospital, Philadelphia, PA (United States)

    2016-06-15

    Purpose: To correct in-vivo metal-oxide-semiconductor field-effect transistor (MOSFET) dosimeters dependence on X-ray energy, dose and dose rate, and temperature in order to measure doses or exposures on several anatomic points of interest undergoing some routine radiographs. Methods: A mobile MOSFET system (BEST Medical) was carefully calibrated with X-ray at kVp of 70, 80, 100, 120, and 138 kVp, phantom temperatures at 0, 21, and 43 oC, and exposure range from 0.01 to 10 R confirmed with Raysafe and RadCal dosimeters. The MOSFETS were placed on the midline bladder or uterus, left pelvic iliac artery, left abdominal above iliac crest, abdominal midline anterior at inferior margin of stomach, and left pectoral of a large and a small body-size cadavers undergoing AP/PA chest and lumber spine radiographs using manual and automatic exposure control (AEC) with and without lead shielding. MOSTFETs and TLD chips were also placed on the stomach, sigmoid, pubic symphysis, left and right pelvic walls of another cadaver for AP pelvic manual or AEC radiography prior to and after a left hip metal implant. Results: Individual MOSFET detectors had various low-dose limits in ranged from 0.03 to 0.08 R, nonlinear response to X-ray energy, and significant temperature effect of 15%. By accumulating 10 manual exposures and 20 AEC exposures, we achieved dose measured accuracy of 6%. There were up to 8 fold increases for AEC exposure of spine and chest X-ray procedure from no shielding to with shielding. For pelvic radiography, exposure to public symphysis was the highest even higher than that of the skin. After hip implant, AEC pelvic radiograph increase exposure by 30 to 200% consistent with results of TLDs. Conclusion: Dependence of energy, temperature and dose limit were accurately corrected. We have found significant exposure for those clinical pr°ocedures and the study provided evidences for developing new clinical procedures.

  5. Dose area product measurement for diagnostic reference levels and analysis of patient dose in dental radiography

    International Nuclear Information System (INIS)

    Han, S.; Lee, B.; Shin, G.; Choi, J.; Kim, J.; Park, C.; Park, H.; Lee, K.; Kim, Y.

    2008-01-01

    In this study, diagnostic reference levels (DRLs) were suggested and patient doses were analysed through the dose-area product value in dental radiography. In intraoral radiography, at three sites, i.e. molar, premolar and incisor on the maxilla and acquired third quartile values: 55.5, 46 and 36.5 mGy cm 2 , respectively, were measured. In panoramic, cephalo-metric and cone beam computed tomography, the values were 120.3, 146 and 3203 mGy cm 2 (16 x 18 cm), respectively. It has been shown that, in intraoral radiography, the patient dose changes proportionally to the value of mA s, but the change in extra-oral radiography in response to mA s could not be confirmed. The authors could confirm, however, the difference in dose according to the manufacturer in all dental radiography examinations, except for panoramic radiography. Depending on the size of hospital, there were some differences in patient dose in intraoral radiography, but no difference in patient dose in extra-oral radiography. (authors)

  6. Technical Note: Out-of-field dose measurement at near surface with plastic scintillator detector.

    Science.gov (United States)

    Bourgouin, Alexandra; Varfalvy, Nicolas; Archambault, Louis

    2016-09-08

    Out-of-field dose depends on multiple factors, making peripheral dosimetry com-plex. Only a few dosimeters have the required features for measuring peripheral dose. Plastic scintillator dosimeters (PSDs) offer numerous dosimetric advantages as required for out-of-field dosimetry. The purpose of this study is to determine the potential of using PSD as a surface peripheral dosimeter. Measurements were performed with a parallel-plate ion chamber, a small volume ion chamber, and with a PSD. Lateral-dose measurements (LDM) at 0.5 cm depth and depth-dose curve (PDD) were made and compared to the dose calculation provided by a treatment planning system (TPS). This study shows that a PSD can measure a dose as low as 0.51 ± 0.17 cGy for photon beam and 0.58 ± 0.20 cGy for electron beam with a difference of 0.2 and 0.1 cGy compared to a parallel-plate ion chamber. This study demonstrates the potential of using PSD as an out-of-field dosimeter since measure-ments with PSD avoid averaging over a too-large depth, at 1 mm diameter, and can make precise measurement at very low dose. Also, electronic equilibrium is easier to reach with PSD due to its small sensitive volume and its water equivalence. © 2016 The Authors.

  7. Efficient and reliable 3D dose quality assurance for IMRT by combining independent dose calculations with measurements

    International Nuclear Information System (INIS)

    Visser, R.; Wauben, D. J. L.; Godart, J.; Langendijk, J. A.; Veld, A. A. van't; Korevaar, E. W.; Groot, M. de

    2013-01-01

    Purpose: Advanced radiotherapy treatments require appropriate quality assurance (QA) to verify 3D dose distributions. Moreover, increase in patient numbers demand efficient QA-methods. In this study, a time efficient method that combines model-based QA and measurement-based QA was developed; i.e., the hybrid-QA. The purpose of this study was to determine the reliability of the model-based QA and to evaluate time efficiency of the hybrid-QA method. Methods: Accuracy of the model-based QA was determined by comparison of COMPASS calculated dose with Monte Carlo calculations for heterogeneous media. In total, 330 intensity modulated radiation therapy (IMRT) treatment plans were evaluated based on the mean gamma index (GI) with criteria of 3%/3mm and classification of PASS (GI ≤ 0.4), EVAL (0.4 0.6), and FAIL (GI ≥ 0.6). Agreement between model-based QA and measurement-based QA was determined for 48 treatment plans, and linac stability was verified for 15 months. Finally, time efficiency improvement of the hybrid-QA was quantified for four representative treatment plans. Results: COMPASS calculated dose was in agreement with Monte Carlo dose, with a maximum error of 3.2% in heterogeneous media with high density (2.4 g/cm 3 ). Hybrid-QA results for IMRT treatment plans showed an excellent PASS rate of 98% for all cases. Model-based QA was in agreement with measurement-based QA, as shown by a minimal difference in GI of 0.03 ± 0.08. Linac stability was high with an average GI of 0.28 ± 0.04. The hybrid-QA method resulted in a time efficiency improvement of 15 min per treatment plan QA compared to measurement-based QA. Conclusions: The hybrid-QA method is adequate for efficient and accurate 3D dose verification. It combines time efficiency of model-based QA with reliability of measurement-based QA and is suitable for implementation within any radiotherapy department.

  8. PTTL Dose Re-estimation Applied to Quality Control in TLD-100 Based Personal Dosimetry

    International Nuclear Information System (INIS)

    Muniz, J.L.; Correcher, V.; Delgado, A.

    1999-01-01

    A new method for quality control of dose performance in Personal Dosimetry using TLD-100 is presented. This method consists of the application of dose reassessment techniques based on phototransferred thermoluminescence (PTTL). Reassessment is achieved through a second TL readout of the dosemeters worn by the controlled workers, after a reproducible UV exposure. Recent refinements in the PTTL technique developed in our laboratory allow reassessing doses as low as 0.2 mSv, thus extending the reassessment capability to the entire dose range that must be monitored in personal dosimetry. After a one month exposure, even purely environmental doses can be reassessed. This method can be applied for either re-estimation of single doses or of the total dose accumulated after a number of exposures and dose measurements. Several tests to reconfirm low doses in normal working conditions for personal dosimetry have been performed. Each test consisted of several cycles of exposure and TL evaluations and a final PTTL re-estimation of the total accumulated dose in those cycles. The results obtained always showed very good agreement between the sum of the partial doses and the total reassessed dose. The simplicity of the method and the possibility of re-evaluating the doses assessed to the workers employing their own dosemeters are advantageous features to be considered in designing systems for the determination of real performance in personal dosimetry. (author)

  9. In vivo measurement of radiation dose during radiotherapy in breast cancer patients using MOSFET dosimeter

    International Nuclear Information System (INIS)

    Wang Lili; Tu Yu; Zhou Juying; Lu Ye; Xu Xiaoting; Li Li; Qin Songbing

    2011-01-01

    Objective: The purpose of the study was to observe and analysis the actual dosage of patients with breast cancer using metal oxide semiconductor field effect transistor (MOSFET) detector. Methods: First, Phantom measurements were performed to investigate dose distribution in the area of the junction in a half-field matching method and the influence of factors related to the accelerator. In vivo dose measurements were performed for patients with breast cancer to investigate the skin dose and the junction of supraclavicular-axillary field and tangential field in 6 MV X-ray beams. Results: Phantom measurements showed that the relative deviation in the junction were within ±3%, and the dose distributions in the junction area depended on the matching field direction (x or y). In vivo measurement of tangential region for patients showed that, the maximum dose deviation between measurement and calculation was -30.39%,the minimum deviation was -18.85%, the average dose deviation was -24.76%. The dose deviation of tangential fields for patients with breast-conserving surgery was larger than that patients with radical surgery (t =2.40, P<0.05), while dose deviation of supraclavicular-axillary fields was not significantly different. The average values of 15 fraction in the junction area showed more stable than one individual measurement. Conclusions: It is important to real-time, in vivo measurement of radiation dose during radiotherapy in patients with breast cancer, and change treatment plan in time, to ensure the accuracy of target dose. (authors)

  10. Dose Measurements in a 20-J Repetitive Plasma Focus

    Science.gov (United States)

    Goudarzi, S.; Babaee, H.; Esmaeli, A.; Nasiri, A.; Mazandarani, A.

    2018-02-01

    In this article, the results of X-ray dose measurements executed using thermoluminescent dosimeters in experiments with a very small (20 J) repetitive plasma focus device named SORENA-1 are presented and analyzed. The working gas in these experiments was Argon. Also, pinch formation in experiments with this device has been observed. This device has been designed and constructed in Plasma and Nuclear Fusion Research School of Nuclear Science and Technology Research Institute of Iran. From these results, it is concluded that we can do experiments with this device using Ar as working gas all over the working days of year, and a good symmetry for measured dose around the device has been seen.

  11. Eye lens dosimetry for interventional procedures – Relation between the absorbed dose to the lens and dose at measurement positions

    International Nuclear Information System (INIS)

    Geber, Therese; Gunnarsson, Mikael; Mattsson, Sören

    2011-01-01

    This study investigated the relationship between the absorbed dose to the lens of the eye and the absorbed dose at different measurement positions near the eye of interventional radiologists. It also visualised the dose distribution inside the head, both when protective eyewear were used and without such protection. The best position for an eye lens dosimeter was found to be at the side of the head nearest to the radiation source, close to the eye. Positioning the dosimeter at the eyebrow could lead to an underestimation of the lens dose of as much as 45%. The measured dose distribution showed that the absorbed dose to the eye lenses was high compared to the other parts of the head, which stresses the importance of wearing protective eyewear. However, many models of eyewear were found to be deficient as the radiation could slip through at several places, e.g. at the cheek. The relationship between the absorbed dose to the lens and the kerma-area-product (P KA ) delivered to the patient was also studied.

  12. Is the dose equivalent index a quantity to be measured

    International Nuclear Information System (INIS)

    Wagner, S.R.

    1980-01-01

    ICRP introduced the concept of Effective Dose Equivalent H(sub)E and fixed the basic limits of radiation exposure in terms of H(sub)I. As H(sub)E cannot be measured, ICRP stated that with external exposure to penetrating radiation the limitation of the Dose Equivalent Index H(sub)I would afford at least as good a level of protection. However, difficulties arise in measuring H(sub)I and in calibrating instruments in terms of H(sub)I, since the height and location of the dose equivalent maximum in the sphere which is the phantom used in the definition of H(sub)I, depend on the energy and the angular distribution of the incident radiation. That is, H(sub)I is not an additive quantity relative to the partial H(sub)I(sub)i-values of the different energy and angular components. Hence, 1) the distribution of dose equivalent in the sphere must be measured in full for a determination of H(sub)I, and 2) it is not possible to calibrate an instrument which does not exhibit the scattering and absorption properties of the sphere, consistently for arbitrary radiation fields in terms of H(sub)I. Thus the calibration in an unidirectional beam would infer an uncertainty which may amount to a factor of up to 4. This would hardly be tolerable as a base for radiation protection provisions. An alternative is to introduce operational quantities which are additive, e.g. 1) the sum of maxima of the dose equivalent distributions in the sphere produced by different radiation components, and 2) the mean dose equivalent in the sphere. Their relation to H(sub)E for different types of radiation and consequences on secondary limits are discussed. (H.K.)

  13. Microscopic Measurements of Axial Accumulation of Red Blood Cells in Capillary Flows Effects of Deformability

    Science.gov (United States)

    Sasaki, Takahiro; Seki, Junji; Itano, Tomoaki; Sugihara-Seki, Masako

    2017-11-01

    In the microcirculation, red blood cells (RBCs) are known to accumulate in the region near the central axis of microvessels, which is called the ``axial accumulation''. Although this behavior of RBCs is considered to originate from high deformability of RBCs, there have been few experimental studies on the mechanism. In order to elucidate the effect of RBC deformability on the axial accumulation, we measured the cross-sectional distributions of RBCs flowing through capillary tubes with a high spatial resolution by a newly devised observation system for intact and softened RBCs as well as hardened RBCs to various degrees. It was found that the intact and softened RBCs are concentrated in the small area centered on the tube axis, whereas the hardened RBCs are dispersed widely over the tube cross section dependent on the degree of hardness. These results demonstrate clearly the essential role of the deformability of RBCs in the ``axial accumulation'' of RBCs. JSPS KAKENHI Grant Number 17H03176, Kansai University ORDIST group funds.

  14. Routine measurement of dose to the bladder: still an utopy?

    International Nuclear Information System (INIS)

    Schaeken, B.; Goor, C.; Weyngaert, D. van den; Middelheim, A.Z.

    1996-01-01

    Dosimetry with alanine is based on the relative and non destructive measurement of stable free radicals produced by radiation. The flexibility of the method (linear dose response, no energy dependence, no dose rate dependence) as well as in detector design makes this method very suited as in vivo dosimetry system for brachytherapy. Absorbed dose to the detector is measured as the signal intensity of the central line of the electron paramagnetic resonance (EPR) powder spectrum of alanine. The dose at the bladder reference point (ICRU 38) can be measured with no additional inconvenience to the patient using a liquid alanine detector (natural oil with alanine crystals of size less than 200 mm) as follows: the balloon of the Foley catheter is filled with ± 7 cc of liquid detector instead of a radio-opaque fluid. By sedimentation the alanine crystals are collected at the posterior surface of the balloon in the vicinity of the bladder reference point. After the treatment the detector is recuperated from the Foley catheter and read out using a small quartz tube. In vitro measurements revealed 1) a perfect linear dose response in the range between 2 Gy and 5 Gy; 2) highly reproducible measurements: 3% (1s) at 1 Gy, 0.3% (1s) at 50 Gy; 3) a minor quantity of oil is leaking through the balloon wall which we expect is of no harm to the patient; 4) retrieving the irradiated alanine crystals from the Foley catheter reduces the EPR signal with a factor 0.927 ± 0.003 (1s); 5) subsequent mixing followed by centrifuge of the detector fluid will result in an EPR signal stable within ± 1% (1s); 6) the detector fluid shows an excellent EPR stability in a period of months after irradiation. We only recently obtained permission of the ethical committee to use this technique in vivo; the results of at least one patient will be discussed

  15. Gamma irradiator dose mapping: a Monte Carlo simulation and experimental measurements

    International Nuclear Information System (INIS)

    Rodrigues, Rogerio R.; Ribeiro, Mariana A.; Grynberg, Suely E.; Ferreira, Andrea V.; Meira-Belo, Luiz Claudio; Sousa, Romulo V.; Sebastiao, Rita de C.O.

    2009-01-01

    Gamma irradiator facilities can be used in a wide range of applications such as biological and chemical researches, food treatment and sterilization of medical devices and products. Dose mapping must be performed in these equipment in order to establish plant operational parameters, as dose uniformity, source utilization efficiency and maximum and minimum dose positions. The isodoses curves are generally measured using dosimeters distributed throughout the device, and this procedure often consume a large amount of dosimeters, irradiation time and manpower. However, a detailed curve doses identification of the irradiation facility can be performed using Monte Carlo simulation, which reduces significantly the monitoring with dosimeters. The present work evaluates the absorbed dose in the CDTN/CNEN Gammacell Irradiation Facility, using the Monte Carlo N-particles (MCNP) code. The Gammacell 220, serial number 39, was produced by Atomic Energy of Canada Limited and was loaded with sources of 60 Co. Dose measurements using TLD and Fricke dosimeters were also performed to validate the calculations. The good agreement of the results shows that Monte Carlo simulations can be used as a predictive tool of irradiation planning for the CDTN/CNEN Gamma Cell Irradiator. (author)

  16. The precision of radiotherapy in Gliwice, Poland, estimated by in vivo dose measurements

    International Nuclear Information System (INIS)

    Orlef, A.; Lobodziec, W.; Maniakowski, Z.

    1995-01-01

    The aim of this work was to evaluate the precision of irradiation using gamma Co-60 Philips Unites and linear accelerators Neptun 10p and Saturne II+ which generate X-rays of 9MV and 23MV respectively. This work has been undertaken for the reason that the effect of radiotherapy of cancer is strongly dependent of the precision of the dose delivery to a patient. The in vivo dose measurements were performed using a p-type silicon diodes (EDE-5, EDP-20, EDP-30) connected to a DPD-510 electrometer (Scanditronix). The diodes were calibrated by comparison their response to a 0.6cm 3 ionization chamber (NE 2571) placed at the relevant depth in the phantom. The entrance and exit dose calibration factors have been determined for reference conditions (constant SSD, field, temperature, ...). For conditions different from reference one the correction factors have been evaluated. The 855 in vivo dose measurements of entrance dose were performed. The histograms of percentage differences between measured and planed entrance dose has been constructed and analyzed. The average values of such differences were: -1.3%, 4.0%, -0.9% for gamma Co-60, X 9MV, X 23MV, respectively. These values can be interpreted as systematic uncertainties. The standard deviations (SD) were found as: 3.1%, 4.1%, 3.5%. These parameters can be considered as a random uncertainties. The 546 cases of dose at the reference point for head and neck cancer have been evaluated taking into account the entrance and exit measured doses. The average difference between those values and planned one was 1.3% and SD = 5.1%. There were observed the changes of the dimensions of the irradiated tissue block during the radiotherapy. This had a significant influence on the differences between delivered (measured) and planed doses at reference point

  17. Measurement and modeling of out-of-field doses from various advanced post-mastectomy radiotherapy techniques

    Science.gov (United States)

    Yoon, Jihyung; Heins, David; Zhao, Xiaodong; Sanders, Mary; Zhang, Rui

    2017-12-01

    More and more advanced radiotherapy techniques have been adopted for post-mastectomy radiotherapies (PMRT). Patient dose reconstruction is challenging for these advanced techniques because they increase the low out-of-field dose area while the accuracy of out-of-field dose calculations by current commercial treatment planning systems (TPSs) is poor. We aim to measure and model the out-of-field radiation doses from various advanced PMRT techniques. PMRT treatment plans for an anthropomorphic phantom were generated, including volumetric modulated arc therapy with standard and flattening-filter-free photon beams, mixed beam therapy, 4-field intensity modulated radiation therapy (IMRT), and tomotherapy. We measured doses in the phantom where the TPS calculated doses were lower than 5% of the prescription dose using thermoluminescent dosimeters (TLD). The TLD measurements were corrected by two additional energy correction factors, namely out-of-beam out-of-field (OBOF) correction factor K OBOF and in-beam out-of-field (IBOF) correction factor K IBOF, which were determined by separate measurements using an ion chamber and TLD. A simple analytical model was developed to predict out-of-field dose as a function of distance from the field edge for each PMRT technique. The root mean square discrepancies between measured and calculated out-of-field doses were within 0.66 cGy Gy-1 for all techniques. The IBOF doses were highly scattered and should be evaluated case by case. One can easily combine the measured out-of-field dose here with the in-field dose calculated by the local TPS to reconstruct organ doses for a specific PMRT patient if the same treatment apparatus and technique were used.

  18. A simplified approach for exit dose in vivo measurements in radiotherapy and its clinical application

    International Nuclear Information System (INIS)

    Banjade, D.P.; Shukri, A.; Tajuddin, A.A.; Shrestha, S.L.; Bhat, M.

    2002-01-01

    This is a study using LiF:Mg;Ti thermoluminescent dosimeter (TLD) rods in phantoms to investigate the effect of lack of backscatter on exit dose. Comparing the measured dose with anticipated dose calculated using tissue maximum ratio (TMR) or percentage depth dose (PDD) gives rise to a correction factor. This correction factor may be applied to in-vivo dosimetry results to derive true dose to a point within the patient. Measurements in a specially designed humanoid breast phantom as well as patients undergoing radiotherapy treatment were also been done. TLDs with reproducibility of within ±3% (1 SD) are irradiated in a series of measurements for 6 and 10 MV photon beams from a medical linear accelerator. The measured exit doses for the different phantom thickness for 6 MV beams are found to be lowered by 10.9 to 14.0% compared to the dose derived from theoretical estimation (normalized dose at d max ). The same measurements for 10 MV beams are lowered by 9.0 to 13.5%. The variations of measured exit dose for different field sizes are found to be within 2.5%. The exit doses with added backscatter material from 2 mm up to 15 cm, shows gradual increase and the saturated values agreed within 1.5% with the expected results for both beams. The measured exit doses in humanoid breast phantom as well as in the clinical trial on patients undergoing radiotherapy also agreed with the predicted results based on phantom measurements. The authors' viewpoint is that this technique provides sufficient information to design exit surface bolus to restore build down effect in cases where part of the exit surface is being considered as a target volume. It indicates that the technique could be translated for in vivo dose measurements, which may be a conspicuous step of quality assurance in clinical practice. Copyright (2002) Australasian College of Physical Scientists and Engineers in Medicine

  19. Radiation dose modeling using IGRIP and Deneb/ERGO

    International Nuclear Information System (INIS)

    Vickers, D.S.; Davis, K.R.; Breazeal, N.L.; Watson, R.A.; Ford, M.S.

    1995-01-01

    The Radiological Environment Modeling System (REMS) quantifies dose to humans in radiation environments using the IGRIP (Interactive Graphical Robot Instruction Program) and Deneb/ERGO (Ergonomics) simulation software products. These commercially available products are augmented with custom C code to provide the radiation exposure information to and collect the radiation dose information from the workcell simulations. The emphasis of this paper is on the IGRIP and Deneb/ERGO parts of REMS, since that represents the extension to existing capabilities developed by the authors. Through the use of any radiation transport code or measured data, a radiation exposure input database may be formulated. User-specified IGRIP simulations utilize these database files to compute and accumulate dose to human devices (Deneb's ERGO human) during simulated operations around radiation sources. Timing, distances, shielding, and human activity may be modeled accurately in the simulations. The accumulated dose is recorded in output files, and the user is able to process and view this output. REMS was developed because the proposed reduction in the yearly radiation exposure limit will preclude or require changes in many of the manual operations currently being utilized in the Weapons Complex. This is particularly relevant in the area of dismantlement activities at the Pantex Plant in Amarillo, TX. Therefore, a capability was needed to be able to quantify the dose associated with certain manual processes so that the benefits of automation could be identified and understood

  20. Experimental measurement and modeling of snow accumulation and snowmelt in a mountain microcatchment

    Science.gov (United States)

    Danko, Michal; Krajčí, Pavel; Hlavčo, Jozef; Kostka, Zdeněk; Holko, Ladislav

    2016-04-01

    Fieldwork is a very useful source of data in all geosciences. This naturally applies also to the snow hydrology. Snow accumulation and snowmelt are spatially very heterogeneous especially in non-forested, mountain environments. Direct field measurements provide the most accurate information about it. Quantification and understanding of processes, that cause these spatial differences are crucial in prediction and modelling of runoff volumes in spring snowmelt period. This study presents possibilities of detailed measurement and modeling of snow cover characteristics in a mountain experimental microcatchment located in northern part of Slovakia in Western Tatra mountains. Catchment area is 0.059 km2 and mean altitude is 1500 m a.s.l. Measurement network consists of 27 snow poles, 3 small snow lysimeters, discharge measurement device and standard automatic weather station. Snow depth and snow water equivalent (SWE) were measured twice a month near the snow poles. These measurements were used to estimate spatial differences in accumulation of SWE. Snowmelt outflow was measured by small snow lysimeters. Measurements were performed in winter 2014/2015. Snow water equivalent variability was very high in such a small area. Differences between particular measuring points reached 600 mm in time of maximum SWE. The results indicated good performance of a snow lysimeter in case of snowmelt timing identification. Increase of snowmelt measured by the snow lysimeter had the same timing as increase in discharge at catchment's outlet and the same timing as the increase in air temperature above the freezing point. Measured data were afterwards used in distributed rainfall-runoff model MIKE-SHE. Several methods were used for spatial distribution of precipitation and snow water equivalent. The model was able to simulate snow water equivalent and snowmelt timing in daily step reasonably well. Simulated discharges were slightly overestimated in later spring.

  1. Effects of low priming dose irradiation on cell cycle arrest of HepG2 cells caused by high dose irradiation

    International Nuclear Information System (INIS)

    Xia Jingguang; Jin Xiaodong; Chinese Academy of Sciences, Beijing; Li Wenjian; Wang Jufang; Guo Chuanling; Gao Qingxiang

    2005-01-01

    Human hepatoma cells hepG2 were irradiated twice by 60 Co γ-rays with a priming dose of 5 cGy and a higher dose of 3 Gy performed 4h or 8h after the low dose irradiation. Effects of the priming dose irradiation on cell cycle arrest caused by high dose were examined with flow cytometry. Cells in G 2 /M phase accumulated temporarily after the 5 cGy irradiation, and proliferation of tumor cells was promoted significantly by the low dose irradiation. After the 3 Gy irradiation, G 2 phase arrest occurred, and S phase delayed temporally. In comparison with 3 kGy irradiation only, the priming dose delivered 4h prior to the high dose irradiation facilitated accumulation of hepG2 cells in G 2 /M phase, whereas the priming dose delivered 8h prior to the high dose irradiation helped the cells to overcome G 2 arrest. It was concluded that effects of the priming dose treatment on cell cycle arrest caused by high dose irradiation were dependent on time interval between the two irradiations. (authors)

  2. Absolute dose measurement Gafchromic R EBT2 movies. Case Study of Kaposis sarcoma

    International Nuclear Information System (INIS)

    Pereira, L.; Moral, F. del; Meilan, E.; Azevedo Gomes, J. C. de; Tejeiro Garcia, A. G.; Andrade Alvarez, B.; Vazquez, J.; Nieto, I.; Medal, D.; Lopez Medina, A.; Francisco, S.; Salgado, M.; Munoz, V.

    2011-01-01

    Because of its high spatial resolution, low energy dependence and good response over a wide energy range, EBT2 Gafchromic films are widely used in many applications in radiotherapy for measuring relative dose. Despite being the most common use can be used to measure absolute dose. This text is an example of using films as EBT2 for in vivo absolute dose in a Kaposis sarcoma.

  3. Accumulative behavior of radioactive cesium during the incineration of municipal solid waste

    International Nuclear Information System (INIS)

    Mizuhara, Shinji; Kawamoto, Katsuya; Maeseto, Tomoharu; Kuramochi, Hidetoshi; Osako, Masahiro

    2015-01-01

    Understanding the long-term accumulation behavior of radioactive cesium (r- Cs) in municipal solid waste (MSW) incineration plants is important for safety management of them. In this study, first, not only air dose rate but also r-Cs activity in wall adhesion dust at different point in the inside of a MSW incineration plant were measured. The results showed that higher amounts of the Cs were observed in the surface layer of refractory and that higher air dose ratios were obtained in the upstream region in incineration process. However, the Cs content of adhered dust onto the surface material of incineration equipment was higher in downstream than upstream because of the decrease of flue gas temperature. (author)

  4. A phantom based method for deriving typical patient doses from measurements of dose-area product on populations of patients

    International Nuclear Information System (INIS)

    Chapple, C.-L.; Broadhead, D.A.

    1995-01-01

    One of the chief sources of uncertainty in the comparison of patient dosimetry data is the influence of patient size on dose. Dose has been shown to relate closely to the equivalent diameter of the patient. This concept has been used to derive a prospective, phantom based method for determining size correction factors for measurements of dose-area product. The derivation of the size correction factor has been demonstrated mathematically, and the appropriate factor determined for a number of different X-ray sets. The use of phantom measurements enables the effect of patient size to be isolated from other factors influencing patient dose. The derived factors agree well with those determined retrospectively from patient dose survey data. Size correction factors have been applied to the results of a large scale patient dose survey, and this approach has been compared with the method of selecting patients according to their weight. For large samples of data, mean dose-area product values are independent of the analysis method used. The chief advantage of using size correction factors is that it allows all patient data to be included in a survey, whereas patient selection has been shown to exclude approximately half of all patients. (author)

  5. Carrier accumulation and depletion in point-contact capacitance-voltage measurements

    Science.gov (United States)

    Naitou, Yuichi

    2017-11-01

    Scanning capacitance microscopy (SCM) is a variation of atomic force microscopy in which a conductive probe tip detects the bias modulated capacitance for the purpose of measuring the nanoscale semiconductor carrier concentration. SCM can be regarded as a point-contact capacitance-voltage system, and its capacitance-voltage properties are different from those of a conventional parallel-plate capacitor. In this study, the charge accumulation and depletion behavior of a semiconductor sample were closely investigated by SCM. By analyzing the tip-sample approach curve, the effective probe tip area and charge depletion depth could be quantitatively determined.

  6. Effect of intra-fraction motion on the accumulated dose for free-breathing MR-guided stereotactic body radiation therapy of renal-cell carcinoma

    Science.gov (United States)

    Stemkens, Bjorn; Glitzner, Markus; Kontaxis, Charis; de Senneville, Baudouin Denis; Prins, Fieke M.; Crijns, Sjoerd P. M.; Kerkmeijer, Linda G. W.; Lagendijk, Jan J. W.; van den Berg, Cornelis A. T.; Tijssen, Rob H. N.

    2017-09-01

    Stereotactic body radiation therapy (SBRT) has shown great promise in increasing local control rates for renal-cell carcinoma (RCC). Characterized by steep dose gradients and high fraction doses, these hypo-fractionated treatments are, however, prone to dosimetric errors as a result of variations in intra-fraction respiratory-induced motion, such as drifts and amplitude alterations. This may lead to significant variations in the deposited dose. This study aims to develop a method for calculating the accumulated dose for MRI-guided SBRT of RCC in the presence of intra-fraction respiratory variations and determine the effect of such variations on the deposited dose. For this, RCC SBRT treatments were simulated while the underlying anatomy was moving, based on motion information from three motion models with increasing complexity: (1) STATIC, in which static anatomy was assumed, (2) AVG-RESP, in which 4D-MRI phase-volumes were time-weighted, and (3) PCA, a method that generates 3D volumes with sufficient spatio-temporal resolution to capture respiration and intra-fraction variations. Five RCC patients and two volunteers were included and treatments delivery was simulated, using motion derived from subject-specific MR imaging. Motion was most accurately estimated using the PCA method with root-mean-squared errors of 2.7, 2.4, 1.0 mm for STATIC, AVG-RESP and PCA, respectively. The heterogeneous patient group demonstrated relatively large dosimetric differences between the STATIC and AVG-RESP, and the PCA reconstructed dose maps, with hotspots up to 40% of the D99 and an underdosed GTV in three out of the five patients. This shows the potential importance of including intra-fraction motion variations in dose calculations.

  7. Absolute and relative dose measurements with Gafchromic trade mark sign EBT film for high energy electron beams with different doses per pulse

    International Nuclear Information System (INIS)

    Fiandra, Christian; Ragona, Riccardo; Ricardi, Umberto; Anglesio, Silvia; Giglioli, Francesca Romana

    2008-01-01

    The authors have evaluated the accuracy, in absolute and relative dose measurements, of the Gafchromic trade mark sign EBT film in pulsed high-energy electron beams. Typically, the electron beams used in radiotherapy have a dose-per-pulse value of less than 0.1 mGy/pulse. However, very high dose-per-pulse electron beams are employed in certain linear accelerators dedicated to intraoperatory radiation therapy (IORT). In this study, the absorbed dose measurements with Gafchromic trade mark sign EBT in both low (less than 0.3 mGy per pulse) and high (30 and 70 mGy per pulse) dose-per-pulse electron beams were compared with ferrous sulfate chemical Fricke dosimetry (operated by the Italian Primary Standard Dosimetry Laboratory), a method independent of the dose per pulse. A summary of Gafchromic trade mark sign EBT in relative and absolute beam output determination is reported. This study demonstrates the independence of Gafchromic trade mark sign EBT absorption as a function of dose per pulse at different dose levels. A good agreement (within 3%) was found with Fricke dosimeters for plane-base IORT applicators. Comparison with a diode detector is presented for relative dose measurements, showing acceptable agreement both in the steep dose falloff zone and in the homogeneous dose region. This work also provides experimental values for recombination correction factor (K sat ) of a Roos (plane parallel) ionization chamber calculated on the basis of theoretical models for charge recombination.

  8. Biophysical dose measurement using electron paramagnetic resonance in rodent teeth

    International Nuclear Information System (INIS)

    Khan, R.F.H.; Rink, W.J.; Boreham, D.R.

    2003-01-01

    Electron paramagnetic resonance (EPR) dosimetry of human tooth enamel has been widely used in measuring radiation doses in various scenarios. However, there are situations that do not involve a human victim (e.g. tests for suspected environmental overexposures, measurements of doses to experimental animals in radiation biology research, or chronology of archaeological deposits). For such cases we have developed an EPR dosimetry technique making use of enamel of teeth extracted from mice. Tooth enamel from both previously irradiated and unirradiated mice was extracted and cleaned by processing in supersaturated KOH aqueous solution. Teeth from mice with no previous irradiation history exhibited a linear EPR response to the dose in the range from 0.8 to 5.5 Gy. The EPR dose reconstruction for a preliminarily irradiated batch resulted in the radiation dose of (1.4±0.2) Gy, which was in a good agreement with the estimated exposure of the teeth. The sensitivity of the EPR response of mouse enamel to gamma radiation was found to be half of that of human tooth enamel. The dosimetric EPR signal of mouse enamel is stable up at least to 42 days after exposure to radiation. Dose reconstruction was only possible with the enamel extracted from molars and premolars and could not be performed with incisors. Electron micrographs showed structural variations in the incisor enamel, possibly explaining the large interfering signal in the non-molar teeth

  9. Estimation of individual doses from external exposures and dose-group classification of cohort members in high background radiation area in Yangjiang, China

    International Nuclear Information System (INIS)

    Yuan Yongling; Shen Hong; Sun Quanfu; Wei Luxin

    1999-01-01

    Objective: In order to estimate annual effective doses from external exposures in the high background radiation area (HBRA) and in the control area (CA) , the authors measured absorbed dose rates in air from terrestrial gamma radiation with different dosimeters. A dose group classification was an important step for analyzing the dose effects relationship among the cohort members in the investigated areas. The authors used the hamlet specific average annual effective doses of all the 526 hamlets in the investigated areas. A classification of four dose groups was made for the cohort members (high, moderate, low and control) . Methods: For the purpose of studying the dose effect relationships among the cohort members in HBRA and CA, it would be ideal that each subject has his own record of individual accumulated doses received before the evaluation. However, rt is difficult to realize it in practice (each of 106517 persons should wear TLD for a long time) . Thus the authors planned two sets of measurements. Firstly, to measure the environmental dose rates (outdoor, indoor, over the bed) in every hamlet of the investigated area (526 hamlets) , considering the occupancy factors for males and females of different age groups to convert to the annual effective dose from the data of dose rates. Secondly, to measure the individual cumulative dose with TLD for part of the subjects in the investigated areas. Results: Based on the two sets of measurements, the estimates of average annual effective doses in HBRA were 211.86 and 206.75 x 10 -5 Sv/a, respectively, 68.60 and 67.11 x 10 -5 Sv/a, respectively(gamma radiation only) . The intercomparison between these two sets of measurement showed that they were in good correlation. Thus the authors are able to yield the equations of linear regression: Y = 0.9937 + 6.0444, r = 0.9949. Conclusions: The authors took the value obtained from direct measurement as 'standard' , and 15 % for uncertainty of measurement. Since the estimates of

  10. Guideline values for skin decontamination measures based on nuclidspecific dose equivalent rate factors

    International Nuclear Information System (INIS)

    Pfob, H.; Heinemann, G.

    1992-01-01

    Corresponding dose equivalent rate factors for various radionuclides are now available for determining the skin dose caused by skin contamination. These dose equivalent rate factors take into account all contributions from the types of radiation emitted. Any limits for skin decontamination measures are nowhere contained or determined yet. However, radiological protection does in practice require at least guideline values in order to prevent unsuitable or detrimental measures that can be noticed quite often. New calculations of dose equivalent rate factors for the skin now make the recommendation of guideline values possible. (author)

  11. Radiation doses measured by TLD (thermo luminescent dosimeter) in x-ray examination

    International Nuclear Information System (INIS)

    Yamamoto, Seiichi; Hiraki, Motoji; Murakami, Shozo; Nishikawa, Naozo; Yagi, Takayuki

    1977-01-01

    By means of TLD, we measured the radiation doses to the skin in the central area of the field of radiation and doses scattered outside of the radiation field, utilizing a phantom to define a suitable radiation field. Clinically, when radiography of the gall bladder and the chest was done, we measured both the radiation doses of the central skin area where radiation was done and the skin above the area of the female gonads. In radiography of the chest, the radiation doses to the skin area above the female gonads situate was under 0.1 mR. When female gonads are less than 15 cm from the margin of the radiation field of the radiation dose can be decreased by 30% if gum sheets containing lead are used to cover the skin area outside the radiation field. (auth.)

  12. On kinetics of paramagnetic radiation defects accumulation in beryllium ceramics

    International Nuclear Information System (INIS)

    Polyakov, A.I.; Ryabikin, Yu.A.; Zashkvara, O.V.; Bitenbaev, M.I.; Petykhov, Yu.V.

    1999-01-01

    Results of paramagnetic radiation defects concentration dependence study in beryllium ceramics from gamma-irradiation dose ( 60 Co) within interval 0-100 Mrem are cited. Obtained dose dependence has form of accumulation curve with saturation typical of for majority of solids (crystals, different polymers, organic substances and others) , in which under irradiation occur not only formation of paramagnetic radiation defects, but its destruction due to recombination and interaction with radiation fields. Analysis of accumulation curve by the method of distant asymptotics allows to determine that observed in gamma-irradiated beryllium ceramics double line of electron spin resonance is forming of two types of paramagnetic radiation defects. It was defined, that sum paramagnetic characteristics of beryllium ceramics within 1-100 Mrad gamma- irradiation dose field change insignificantly and define from first type of paramagnetic radiation defects

  13. Measurement of Patient Dose from Computed Tomography Using Physical Anthropomorphic Phantom

    International Nuclear Information System (INIS)

    Jang, Ki Won; Lee, Jae Ki; Kim, Jong Kyung

    2005-01-01

    The computed tomography (CT) provides a high quality in images of human body but contributes relatively high patient dose compared with the conventional X-ray examination. Furthermore, the frequency of CT examination has been increasing in Korea for the last decade owing to the national health insurance benefits. Increasing concerns about high patient dose from CT have stimulated a great deal of researches on dose assessment, which many of these are based on the Monte Carlo simulation. But in this study, absorbed doses and effective dose of patient undergoing CT examination were determined experimentally using anthropomorphic physical phantom and the measured results are compared with those from Monte Carlo calculation

  14. Quantification of dose uncertainties for the bladder in prostate cancer radiotherapy based on dominant eigenmodes

    Science.gov (United States)

    Rios, Richard; Acosta, Oscar; Lafond, Caroline; Espinosa, Jairo; de Crevoisier, Renaud

    2017-11-01

    In radiotherapy for prostate cancer the dose at the treatment planning for the bladder may be a bad surrogate of the actual delivered dose as the bladder presents the largest inter-fraction shape variations during treatment. This paper presents PCA models as a virtual tool to estimate dosimetric uncertainties for the bladder produced by motion and deformation between fractions. Our goal is to propose a methodology to determine the minimum number of modes required to quantify dose uncertainties of the bladder for motion/deformation models based on PCA. We trained individual PCA models using the bladder contours available from three patients with a planning computed tomography (CT) and on-treatment cone-beam CTs (CBCTs). Based on the above models and via deformable image registration (DIR), we estimated two accumulated doses: firstly, an accumulated dose obtained by integrating the planning dose over the Gaussian probability distribution of the PCA model; and secondly, an accumulated dose obtained by simulating treatment courses via a Monte Carlo approach. We also computed a reference accumulated dose for each patient using his available images via DIR. Finally, we compared the planning dose with the three accumulated doses, and we calculated local dose variability and dose-volume histogram uncertainties.

  15. Exposure dose response relationships of the freshwater bivalve Hyridella australis to cadmium spiked sediments

    International Nuclear Information System (INIS)

    Marasinghe Wadige, Chamani P.M.; Maher, William A.; Taylor, Anne M.; Krikowa, Frank

    2014-01-01

    Highlights: • The exposure–dose–response approach was used to assess cadmium exposure and toxicity. • Accumulated cadmium in H. australis reflected the sediment cadmium exposure. • Spill over of cadmium into the biologically active pool was observed. • Increased cadmium resulted in measurable biological effects. • H. australis has the potential to be a cadmium biomonitor in freshwater environments. - Abstract: To understand how benthic biota may respond to the additive or antagonistic effects of metal mixtures in the environment it is first necessary to examine their responses to the individual metals. In this context, laboratory controlled single metal-spiked sediment toxicity tests are useful to assess this. The exposure–dose–response relationships of Hyridella australis to cadmium-spiked sediments were, therefore, investigated in laboratory microcosms. H. australis was exposed to individual cadmium spiked sediments (<0.05 (control), 4 ± 0.3 (low) and 15 ± 1 (high) μg/g dry mass) for 28 days. Dose was measured as cadmium accumulation in whole soft body and individual tissues at weekly intervals over the exposure period. Dose was further examined as sub-cellular localisation of cadmium in hepatopancreas tissues. The biological responses in terms of enzymatic and cellular biomarkers were measured in hepatopancreas tissues at day 28. H. australis accumulated cadmium from spiked sediments with an 8-fold (low exposure organisms) and 16-fold (high exposure organisms) increase at day 28 compared to control organisms. The accumulated tissue cadmium concentrations reflected the sediment cadmium exposure at day 28. Cadmium accumulation in high exposure organisms was inversely related to the tissue calcium concentrations. Gills of H. australis showed significantly higher cadmium accumulation than the other tissues. Accumulated cadmium in biologically active and biologically detoxified metal pools was not significantly different in cadmium exposed

  16. The estimation of effective doses using measurement of several relevant physical parameters from radon exposures

    International Nuclear Information System (INIS)

    Ridzikova, A; Fronka, A.; Maly, B.; Moucka, L.

    2003-01-01

    In the present investigation, we will be study the dose relevant factors from continual monitoring in real homes into account getting more accurate estimation of 222 Rn the effective dose. The dose relevant parameters include the radon concentration, the equilibrium factor (f), the fraction (fp) of unattached radon decay products and real time occupancy people in home. The result of the measurement are the time courses of radon concentration that are based on estimation effective doses together with assessment of the real time occupancy people indoor. We found out by analysis that year effective dose is lower than effective dose estimated by ICRP recommendation from the integral measurement that included only average radon concentration. Our analysis of estimation effective doses using measurement of several physical parameters was made only in one case and for the better specification is important to measure in different real occupancy houses. (authors)

  17. Collective dose as a performance measure for occupational radiation protection programs: Issues and recommendations

    International Nuclear Information System (INIS)

    Strom, D.J.; Harty, R.; Hickey, E.E.; Martin, J.B.; Peffers, M.S.; Kathren, R.L.

    1998-07-01

    Collective dose is one of the performance measures used at many US Department of Energy (DOE) contractor facilities to quantitatively assess the objectives of the radiation protection program. It can also be used as a management tool to improve the program for keeping worker doses as low as reasonably achievable (ALARA). Collective dose is used here to mean the sum of all total effective dose equivalent values for all workers in a specified group over a specified time. It is often used as a surrogate estimate of radiological risk. In principle, improvements in radiation protection programs and procedures will result in reduction of collective dose, all other things being equal. Within the DOE, most frequently, a single collective dose number, which may or may not be adjusted for workload and other factors, is used as a performance measure for a contractor. The purpose of this report is to evaluate the use of collective dose as a performance measure for ALARA programs at DOE sites

  18. Comparison and analysis of BNCT radiation dose between gold wire and JCDS measurement

    International Nuclear Information System (INIS)

    Kageji, T.; Mizobuchi, Y.; Nagahiro, S.; Nakagawa, Y.; Kumada, Hiroaki

    2006-01-01

    We compared and evaluated boron neutron capture therapy (BNCT) radiation dose between gold wire measurement and JAERI Computational Dosimetry System (JCDS). Gold wire analysis demonstrates the actual BNCT dose though it dose not reflect the real the maximum and minimum dose in tumor tissue. We can conclude that JCDS is precise and high-reliable dose planning system for BNCT. (author)

  19. A measurement-based generalized source model for Monte Carlo dose simulations of CT scans.

    Science.gov (United States)

    Ming, Xin; Feng, Yuanming; Liu, Ransheng; Yang, Chengwen; Zhou, Li; Zhai, Hezheng; Deng, Jun

    2017-03-07

    The goal of this study is to develop a generalized source model for accurate Monte Carlo dose simulations of CT scans based solely on the measurement data without a priori knowledge of scanner specifications. The proposed generalized source model consists of an extended circular source located at x-ray target level with its energy spectrum, source distribution and fluence distribution derived from a set of measurement data conveniently available in the clinic. Specifically, the central axis percent depth dose (PDD) curves measured in water and the cone output factors measured in air were used to derive the energy spectrum and the source distribution respectively with a Levenberg-Marquardt algorithm. The in-air film measurement of fan-beam dose profiles at fixed gantry was back-projected to generate the fluence distribution of the source model. A benchmarked Monte Carlo user code was used to simulate the dose distributions in water with the developed source model as beam input. The feasibility and accuracy of the proposed source model was tested on a GE LightSpeed and a Philips Brilliance Big Bore multi-detector CT (MDCT) scanners available in our clinic. In general, the Monte Carlo simulations of the PDDs in water and dose profiles along lateral and longitudinal directions agreed with the measurements within 4%/1 mm for both CT scanners. The absolute dose comparison using two CTDI phantoms (16 cm and 32 cm in diameters) indicated a better than 5% agreement between the Monte Carlo-simulated and the ion chamber-measured doses at a variety of locations for the two scanners. Overall, this study demonstrated that a generalized source model can be constructed based only on a set of measurement data and used for accurate Monte Carlo dose simulations of patients' CT scans, which would facilitate patient-specific CT organ dose estimation and cancer risk management in the diagnostic and therapeutic radiology.

  20. A measurement-based generalized source model for Monte Carlo dose simulations of CT scans

    Science.gov (United States)

    Ming, Xin; Feng, Yuanming; Liu, Ransheng; Yang, Chengwen; Zhou, Li; Zhai, Hezheng; Deng, Jun

    2017-03-01

    The goal of this study is to develop a generalized source model for accurate Monte Carlo dose simulations of CT scans based solely on the measurement data without a priori knowledge of scanner specifications. The proposed generalized source model consists of an extended circular source located at x-ray target level with its energy spectrum, source distribution and fluence distribution derived from a set of measurement data conveniently available in the clinic. Specifically, the central axis percent depth dose (PDD) curves measured in water and the cone output factors measured in air were used to derive the energy spectrum and the source distribution respectively with a Levenberg-Marquardt algorithm. The in-air film measurement of fan-beam dose profiles at fixed gantry was back-projected to generate the fluence distribution of the source model. A benchmarked Monte Carlo user code was used to simulate the dose distributions in water with the developed source model as beam input. The feasibility and accuracy of the proposed source model was tested on a GE LightSpeed and a Philips Brilliance Big Bore multi-detector CT (MDCT) scanners available in our clinic. In general, the Monte Carlo simulations of the PDDs in water and dose profiles along lateral and longitudinal directions agreed with the measurements within 4%/1 mm for both CT scanners. The absolute dose comparison using two CTDI phantoms (16 cm and 32 cm in diameters) indicated a better than 5% agreement between the Monte Carlo-simulated and the ion chamber-measured doses at a variety of locations for the two scanners. Overall, this study demonstrated that a generalized source model can be constructed based only on a set of measurement data and used for accurate Monte Carlo dose simulations of patients’ CT scans, which would facilitate patient-specific CT organ dose estimation and cancer risk management in the diagnostic and therapeutic radiology.

  1. Comparative study on skin dose measurement using MOSFET and TLD for pediatric patients with acute lymphatic leukemia.

    Science.gov (United States)

    Al-Mohammed, Huda I; Mahyoub, Fareed H; Moftah, Belal A

    2010-07-01

    The object of this study was to compare the difference of skin dose measured in patients with acute lymphatic leukemia (ALL) treated with total body irradiation (TBI) using metal oxide semiconductor field-effect transistors (mobile MOSFET dose verification system (TN-RD-70-W) and thermoluminescent dosimeters (TLD-100 chips, Harshaw/ Bicron, OH, USA). Because TLD has been the most-commonly used technique in the skin dose measurement of TBI, the aim of the present study is to prove the benefit of using the mobile MOSFET (metal oxide semiconductor field effect transistor) dosimeter, for entrance dose measurements during the total body irradiation (TBI) over thermoluminescent dosimeters (TLD). The measurements involved 10 pediatric patients ages between 3 and 14 years. Thermoluminescent dosimeters and MOSFET dosimetry were performed at 9 different anatomic sites on each patient. The present results show there is a variation between skin dose measured with MOSFET and TLD in all patients, and for every anatomic site selected, there is no significant difference in the dose delivered using MOSFET as compared to the prescribed dose. However, there is a significant difference for every anatomic site using TLD compared with either the prescribed dose or MOSFET. The results indicate that the dosimeter measurements using the MOSFET gave precise measurements of prescribed dose. However, TLD measurement showed significant increased skin dose of cGy as compared to either prescribed dose or MOSFET group. MOSFET dosimeters provide superior dose accuracy for skin dose measurement in TBI as compared with TLD.

  2. The radiation dose from a proposed measurement of arsenic and selenium in human skin

    Energy Technology Data Exchange (ETDEWEB)

    Gherase, Mihai R; Mader, Joanna E; Fleming, David E B, E-mail: mgherase@mta.c [Department of Physics, Mount Allison University, 67 York Street, Sackville, NB E4L 1E6 (Canada)

    2010-09-21

    Dose measurements following 10 min irradiations with a portable x-ray fluorescence spectrometer composed of a miniature x-ray tube and a silicon PiN diode detector were performed using thermoluminescent dosimeters consisting of LiF:Mg,Ti chips of 3 mm diameter and 0.4 mm thickness. The table-top setup of the spectrometer was used for all measurements. The setup included a stainless steel lid which served as a radiation shield. Two rectangular polyethylene skin/soft tissue phantoms with two cylindrical plaster of Paris bone phantoms were used to study the effect of x-ray beam attenuation and backscatter on the measured dose. Eight different irradiation experiments were performed. The average dose rate values measured with TLD chips within a 1 x 1 cm{sup 2} area were between 4.8 and 12.8 mGy min{sup -1}. The equivalent dose for a 1 x 1 cm{sup 2} skin area was estimated to be 13.2 mSv. The maximum measured dose rate values with a single TLD chip were between 7.5 and 25.1 mGy min{sup -1}. The effective dose corresponding to a proposed arsenic/selenium skin measurement was estimated to be 0.13 {mu}Sv for a 2 min irradiation.

  3. SU-E-T-616: Plan Quality Assessment of Both Treatment Planning System Dose and Measurement-Based 3D Reconstructed Dose in the Patient

    International Nuclear Information System (INIS)

    Olch, A

    2015-01-01

    Purpose: Systematic radiotherapy plan quality assessment promotes quality improvement. Software tools can perform this analysis by applying site-specific structure dose metrics. The next step is to similarly evaluate the quality of the dose delivery. This study defines metrics for acceptable doses to targets and normal organs for a particular treatment site and scores each plan accordingly. The input can be the TPS or the measurement-based 3D patient dose. From this analysis, one can determine whether the delivered dose distribution to the patient receives a score which is comparable to the TPS plan score, otherwise replanning may be indicated. Methods: Eleven neuroblastoma patient plans were exported from Eclipse to the Quality Reports program. A scoring algorithm defined a score for each normal and target structure based on dose-volume parameters. Each plan was scored by this algorithm and the percentage of total possible points was obtained. Each plan also underwent IMRT QA measurements with a Mapcheck2 or ArcCheck. These measurements were input into the 3DVH program to compute the patient 3D dose distribution which was analyzed using the same scoring algorithm as the TPS plan. Results: The mean quality score for the TPS plans was 75.37% (std dev=14.15%) compared to 71.95% (std dev=13.45%) for the 3DVH dose distribution. For 3/11 plans, the 3DVH-based quality score was higher than the TPS score, by between 0.5 to 8.4 percentage points. Eight/11 plans scores decreased based on IMRT QA measurements by 1.2 to 18.6 points. Conclusion: Software was used to determine the degree to which the plan quality score differed between the TPS and measurement-based dose. Although the delivery score was generally in good agreement with the planned dose score, there were some that improved while there was one plan whose delivered dose quality was significantly less than planned. This methodology helps evaluate both planned and delivered dose quality. Sun Nuclear Corporation has

  4. SU-E-T-616: Plan Quality Assessment of Both Treatment Planning System Dose and Measurement-Based 3D Reconstructed Dose in the Patient

    Energy Technology Data Exchange (ETDEWEB)

    Olch, A [University of Southern California, Los Angeles, CA (United States)

    2015-06-15

    Purpose: Systematic radiotherapy plan quality assessment promotes quality improvement. Software tools can perform this analysis by applying site-specific structure dose metrics. The next step is to similarly evaluate the quality of the dose delivery. This study defines metrics for acceptable doses to targets and normal organs for a particular treatment site and scores each plan accordingly. The input can be the TPS or the measurement-based 3D patient dose. From this analysis, one can determine whether the delivered dose distribution to the patient receives a score which is comparable to the TPS plan score, otherwise replanning may be indicated. Methods: Eleven neuroblastoma patient plans were exported from Eclipse to the Quality Reports program. A scoring algorithm defined a score for each normal and target structure based on dose-volume parameters. Each plan was scored by this algorithm and the percentage of total possible points was obtained. Each plan also underwent IMRT QA measurements with a Mapcheck2 or ArcCheck. These measurements were input into the 3DVH program to compute the patient 3D dose distribution which was analyzed using the same scoring algorithm as the TPS plan. Results: The mean quality score for the TPS plans was 75.37% (std dev=14.15%) compared to 71.95% (std dev=13.45%) for the 3DVH dose distribution. For 3/11 plans, the 3DVH-based quality score was higher than the TPS score, by between 0.5 to 8.4 percentage points. Eight/11 plans scores decreased based on IMRT QA measurements by 1.2 to 18.6 points. Conclusion: Software was used to determine the degree to which the plan quality score differed between the TPS and measurement-based dose. Although the delivery score was generally in good agreement with the planned dose score, there were some that improved while there was one plan whose delivered dose quality was significantly less than planned. This methodology helps evaluate both planned and delivered dose quality. Sun Nuclear Corporation has

  5. Neutron dose rate at the SwissFEL injector test facility: first measurements

    International Nuclear Information System (INIS)

    Hohmann, E.; Frey, N.; Fuchs, A.; Harm, C.; Hoedlmoser, H.; Luescher, R.; Mayer, S.; Morath, O.; Philipp, R.; Rehmann, A.; Schietinger, T.

    2014-01-01

    At the Paul Scherrer Institute, the new SwissFEL Free Electron Laser facility is currently in the design phase. It is foreseen to accelerate electrons up to a maximum energy of 7 GeV with a pulsed time structure. An injector test facility is operated at a maximum energy of 300 MeV and serves as the principal test and demonstration plant for the SwissFEL project. Secondary radiation is created in unavoidable interactions of the primary beam with beamline components. The resulting ambient dose-equivalent rate due to neutrons was measured along the beamline with different commercially available survey instruments. The present study compares the readings of these neutron detectors (one of them is specifically designed for measurements in pulsed fields). The experiments were carried out in both, a normal and a diagnostic mode of operation of the injector. Measurements were taken at the SwissFEL injector test facility using three different types of commercially available survey instruments for normal and diagnostic mode of operation at different positions inside the accelerator vault. During normal operation, the doses indicated by the different instruments agree within the measurement uncertainty except for the beam dump region. There, due to its limited energy range and high sensitivity, the LB6411 shows significantly lower dose values than the other instruments. The photon background in the vault associated with each pulse causes the scintillator used by the LB6419 to saturate. As a result, only the channel using the delayed 12 C(n,p)12-reaction could be used during the measurements. The highest doses per pulse were measured next to the beam dump and the bunch compressor. For the optimisation of the accelerator, luminescent screens can be inserted into the beam path causing a dose distributed over several metres depending on the screen type. The dose arise to 40 % from neutrons with energies of >20 MeV. Although the charge of each pulse were reduced to decrease

  6. Radiation exposure of radiologists during angiography: Dose measurements outside the lead apron

    International Nuclear Information System (INIS)

    Fischer, H.; Przetak, C.; Teubert, G.; Ewen, K.; Moedder, U.

    1995-01-01

    The aim of this study was to provide practical information to angiographers concerning radiation exposure to body parts not covered by lead aprons. Individual doses to the neck and hands of radiologists measured in micro-Sieverts were obtained during the course of 80 angiographies of various types. The number of diagnostic and interventional procedures, which might lead to exceeding permissible doses, have been calculated. Possibilities of estimating doses during angiography by means of parameters such as screening times were examined statistically. Especially with regard to the hands, estimations of the doses are insufficient (correlation r=0.21). Radiologists who undertake much angiographic and particularly interventional work may reach exposure levels requiring protective measures in addition to lead aprons. (orig.) [de

  7. Measurement of multi-slice computed tomography dose profile with the Dose Magnifying Glass and the MOSkin radiation dosimeter

    International Nuclear Information System (INIS)

    Lian, C.P.L.; Wong, J.H.D.; Young, A.; Cutajar, D.; Petasecca, M.; Lerch, M.L.F.; Rosenfeld, A.B.

    2013-01-01

    This study describes the application of two in-house developed dosimeters, the Dose Magnifying Glass (DMG) and the MOSkin dosimeter at the Centre for Medical Radiation Physics, University of Wollongong, Australia, for the measurement of CT dose profiles for a clinical diagnostic 16-slice MSCT scanner. Two scanner modes were used; axial mode and helical mode, and the effect of varying beam collimation and pitch was studied. With an increase in beam collimation in axial mode and an increase of CT pitch in helical mode, cumulative point dose at scanner isocentre decreased while FWHM increased. There was generally good agreement to within 3% between the acquired dose profiles obtained by the DMG and the film except at dose profile tails, where film over-responded by up to 30% due to its intrinsic depth dose dependence at low doses. -- Highlights: ► This study shows the CT beam profiles acquired with our institution's detectors. ► The DMG is a relative dosimeter calibrated to absolute MOSkin readings. ► There was good agreement between dose profiles acquired by the DMG and the film

  8. Assessment of two-dimensional (2D) and three-dimensional (3D) lower limb measurements in adults: Comparison of micro-dose and low-dose biplanar radiographs

    International Nuclear Information System (INIS)

    Rosskopf, Andrea B.; Pfirrmann, Christian W.A.; Buck, Florian M.

    2016-01-01

    To evaluate reliability of 2D and 3D lower limb measurements in adults using micro-dose compared to low-dose biplanar radiographs(BPR). One hundred patients (mean 54.9 years) were examined twice using micro-dose and low-dose BPR. Length and mechanical axis of lower limbs were measured on the antero-posterior(ap) micro-dose and low-dose images by two independent readers. Femoral and tibial torsions of 50 patients were measured by two independent readers using reconstructed 3D-models based on the micro-dose and low-dose BPR. Intermethod and interreader agreements were calculated using descriptive statistics, intraclass-correlation-coefficient(ICC), and Bland-Altman analysis. Mean interreader-differences on micro-dose were 0.3 cm(range 0-1.0)/ 0.7 (0-2.9) for limb length/axis and 0.4 cm (0-1.0)/0.8 (0-3.3) on low-dose BPR. Mean intermethod-difference was 0.04 cm ± 0.2/0.04 ± 0.6 for limb length/axis. Interreader-ICC for limb length/axis was 0.999/0.991 on micro-dose and 0.999/0.987 on low-dose BPR. Interreader-ICC for micro-dose was 0.879/0.826 for femoral/tibial torsion, for low-dose BPR was 0.924/0.909. Mean interreader-differences on micro-dose/low-dose BPR were 3 (0-13 )/2 (0 -12 ) for femoral and 4 (0-18 )/3 (0 -10 ) for tibial torsion. Mean intermethod-difference was -0.1 ± 5.0/-0.4 ± 2.9 for femoral/tibial torsion. Mean dose-area-product was significantly lower (9.9 times;p < 0.001) for micro-dose BPR. 2D-and 3D-measurements of lower limbs based on micro-dose BPR are reliable and provide a 10-times lower radiation dose. (orig.)

  9. Measurement and assessment of doses from external radiations required for revised radiation protection regulations

    Energy Technology Data Exchange (ETDEWEB)

    Tsujimura, Norio; Kojima, Noboru; Hayashi, Naomi [Japan Nuclear Cycle Development Inst., Tokai, Ibaraki (Japan)

    2001-06-01

    Radiation protection regulations based on the 1990 recommendations of ICRP have been revised and will take effect from Apr., 2001. The major changes concerning on the measurement and assessment of doses from external radiations are as follows. (1) Personal dose equivalent and ambient dose equivalent stated in ICRP Publication 74 are introduced as quantities to be measured with personal dosimeters and survey instruments, respectively. (2) For multiple dosimetry for workers, the compartment weighting factors used for a realistic assessment of effective dose are markedly changed. In advance of the introduction of the new radiation protection regulations, the impacts on workplace and personal monitoring for external radiations by these revisions were investigated. The following results were obtained. (1) A new ambient dose equivalent to neutrons is higher with a factor of 1.2 than the old one for moderated fission neutron spectra. Therefore, neutron dose equivalent monitors for workplace monitoring at MOX fuel for facilities should be recalibrated for measurement of the new ambient dose equivalent. (2) Annual effective doses of workers were estimated by applying new calibration factors to readings of personal dosimeters, worn by workers. Differences between effective doses and effective dose equivalents are small for workers engaged in the fabrication process of MOX fuel. (author)

  10. Measurement and assessment of doses from external radiations required for revised radiation protection regulations

    International Nuclear Information System (INIS)

    Tsujimura, Norio; Kojima, Noboru; Hayashi, Naomi

    2001-01-01

    Radiation protection regulations based on the 1990 recommendations of ICRP have been revised and will take effect from Apr., 2001. The major changes concerning on the measurement and assessment of doses from external radiations are as follows. (1) Personal dose equivalent and ambient dose equivalent stated in ICRP Publication 74 are introduced as quantities to be measured with personal dosimeters and survey instruments, respectively. (2) For multiple dosimetry for workers, the compartment weighting factors used for a realistic assessment of effective dose are markedly changed. In advance of the introduction of the new radiation protection regulations, the impacts on workplace and personal monitoring for external radiations by these revisions were investigated. The following results were obtained. (1) A new ambient dose equivalent to neutrons is higher with a factor of 1.2 than the old one for moderated fission neutron spectra. Therefore, neutron dose equivalent monitors for workplace monitoring at MOX fuel for facilities should be recalibrated for measurement of the new ambient dose equivalent. (2) Annual effective doses of workers were estimated by applying new calibration factors to readings of personal dosimeters, worn by workers. Differences between effective doses and effective dose equivalents are small for workers engaged in the fabrication process of MOX fuel. (author)

  11. 40 CFR 86.000-26 - Mileage and service accumulation; emission measurements.

    Science.gov (United States)

    2010-07-01

    ... accumulated the mileage the manufacturer chose to accumulate on the test vehicle. Fuel economy data generated... determines. Unless the Administrator approves a manufacturer's request to develop specific deterioration... accumulation method is developed by the manufacturer to be consistent with good engineering practice and to...

  12. Review of techniques and detectors used in instruments for field measurement of beta doses and dose rates

    International Nuclear Information System (INIS)

    Jones, A.R.

    1983-01-01

    Generally, field measurements are required to assess the hazard from #betta#-rays before personnel are allowed to occupy a working space or perform a task. Occasionally, the measurements are required for an assessment after a #betta#-ray exposure is suspected to have occurred. Until recently the dose or dose rate have been the quantities of interest but there is now felt to be a need to characterize the energies and directions of the #betta#-rays as well. The purpose of #betta#-dosimetry is the assessment of hazard to superficial tissues (within approx. 10 mm of the surface) and that these tissues may also be exposed simultaneously to other ionizing radiations. The #betta#-dosimetry technique must take account of this. With these uses of field instruments in mind the following detectors, and associated techniques will be discussed in terms of the measurement principles, advantages and limitations: thin-walled ion chambers (sometimes in combination with thick-walled ones or with covers thick enough to prevent penetration of #betta#-particles); thin scintillators, nearly tissue equivalent, to provide a detector analogous to skin; scintillators, thick enough to absorb all the energy of the #betta#-particles (circuitry is required to count pulses according to size to permit calculation of dose or dose rate); silicon diodes with thin detection layers operated as photocurrent generators; silicon diodes, reversed biassed, with pulses counted according to size; and simple pulse counters (e.g., GM counters or silicon diodes with thin windows)

  13. Real-time personal dose monitoring and management system

    International Nuclear Information System (INIS)

    Zhang Zhiyong; Cheng Chang; Yang Huating; Liu Zhengshan; Deng Changming; Li Mei

    2000-01-01

    This paper mainly describes a real-time personal dose monitoring and management system. The system is composed of three parts that include SDM-98 semiconductor detector personal dosimeters, Data Readers and a Management System Software. It can be used for personal dose monitoring and management and other controlling actions in a radioactive controlled area. Adopting semiconductor detector and microcontroller, SDM-98 Personal Dosimeter is used to measure personal accumulated dose equivalent and dose rate caused by X-ray and Gamma ray. The results can be read directly on LCD. All the data stored in dosimeter can be transmitted into a data reader by infrared optical link. The alarm threshold can be adjusted successively in whole range of dose or dose rate. The Data Reader is an intelligent interface between the dosimeter and master computer. The data received from dosimeter will be sent to a master computer through RS-232 serial interface. According to the master computer's order, the Data Reader can turn on the dosimeter's power at entrance and shutdown it at exit. The Management System Software which written by Visual BASIC 5.0 runs on MS Win95. All the measuring data from dosimeters can be analyzed and treated according to requirements and stored in database. Therefore, some figures and tables relative to dose or rate can be shown on screen or printed out. (author)

  14. Current algebras, measures quasi-invariant under diffeomorphism groups, and infinite quantum systems with accumulation points

    Science.gov (United States)

    Sakuraba, Takao

    The approach to quantum physics via current algebra and unitary representations of the diffeomorphism group is established. This thesis studies possible infinite Bose gas systems using this approach. Systems of locally finite configurations and systems of configurations with accumulation points are considered, with the main emphasis on the latter. In Chapter 2, canonical quantization, quantization via current algebra and unitary representations of the diffeomorphism group are reviewed. In Chapter 3, a new definition of the space of configurations is proposed and an axiom for general configuration spaces is abstracted. Various subsets of the configuration space, including those specifying the number of points in a Borel set and those specifying the number of accumulation points in a Borel set are proved to be measurable using this axiom. In Chapter 4, known results on the space of locally finite configurations and Poisson measure are reviewed in the light of the approach developed in Chapter 3, including the approach to current algebra in the Poisson space by Albeverio, Kondratiev, and Rockner. Goldin and Moschella considered unitary representations of the group of diffeomorphisms of the line based on self-similar random processes, which may describe infinite quantum gas systems with clusters. In Chapter 5, the Goldin-Moschella theory is developed further. Their construction of measures quasi-invariant under diffeomorphisms is reviewed, and a rigorous proof of their conjectures is given. It is proved that their measures with distinct correlation parameters are mutually singular. A quasi-invariant measure constructed by Ismagilov on the space of configurations with accumulation points on the circle is proved to be singular with respect to the Goldin-Moschella measures. Finally a generalization of the Goldin-Moschella measures to the higher-dimensional case is studied, where the notion of covariance matrix and the notion of condition number play important roles. A

  15. Evaluation of the 'dose of the day' for IMRT prostate cancer patients derived from portal dose measurements and cone-beam CT

    International Nuclear Information System (INIS)

    Zijtveld, Mathilda van; Dirkx, Maarten; Breuers, Marcel; Kuipers, Ruud; Heijmen, Ben

    2010-01-01

    Purpose: High geometrical and dosimetrical accuracies are required for radiotherapy treatments where IMRT is applied in combination with narrow treatment margins in order to minimize dose delivery to normal tissues. As an overall check, we implemented a method for reconstruction of the actually delivered 3D dose distribution to the patient during a treatment fraction, i.e., the 'dose of the day'. In this article results on the clinical evaluation of this concept for a group of IMRT prostate cancer patients are presented. Materials and methods: The actual IMRT fluence maps delivered to a patient were derived from measured EPID-images acquired during treatment using a previously described iterative method. In addition, the patient geometry was obtained from in-room acquired cone-beam CT images. For dose calculation, a mapping of the Hounsfield Units from the planning CT was applied. With the fluence maps and the modified cone-beam CT the 'dose of the day' was calculated. The method was validated using phantom measurements and evaluated clinically for 10 prostate cancer patients in 4 or 5 fractions. Results: The phantom measurements showed that the delivered dose could be reconstructed within 3%/3 mm accuracy. For prostate cancer patients, the isocenter dose agreed within -0.4 ± 1.0% (1 SD) with the planned value, while for on average 98.1% of the pixels within the 50% isodose surface the actually delivered dose agreed within 3% or 3 mm with the planned dose. For most fractions, the dose coverage of the prostate volume was slightly deteriorated which was caused by small prostate rotations and small inaccuracies in fluence delivery. The dose that was delivered to the rectum remained within the constraints used during planning. However, for two patients a large degrading of the dose delivery was observed in two fractions. For one patient this was related to changes in rectum filling with respect to the planning CT and for the other to large intra-fraction motion during

  16. Process control and dosimetry applied to establish a relation between reference dose measurements and actual dose distribution

    Energy Technology Data Exchange (ETDEWEB)

    Ehlerman, D A.E. [Institute of Process Engineering, Federal Research Centre for Nutrition, Karlsruhe (Germany)

    2001-03-01

    The availability of the first commercial dose level indicator prompted attempts to verify radiation absorbed dose to items under quarantine control (e.g. for insect disinfestation) by some indicator attached to these items. Samples of the new commercial dose level indicators were tested for their metrological properties using gamma and electron irradiation. The devices are suitable for the intended purpose and the subjective judgement whether the threshold dose was surpassed is possible in a reliable manner. The subjective judgements are completely backed by the instrumental results. Consequently, a prototype reader was developed; first tests were successful. The value of dose level indicators and the implications of its use for food or quarantine inspection depends on a link between dose measured (indicated) at the position of such indicator and the characteristic parameters of the frequency distribution of dose throughout the product load i.e. a box or a container or a whole batch of multiple units. Therefore, studies into variability and statistical properties of dose distributions obtained under a range of commercial situations were undertaken. Gamma processing at a commercial multipurpose contract irradiator, electron processing and bremsstrahlung applications at a largescale research facility were included; products were apples, potatoes, wheat, maize, pistachio. Studies revealed that still more detailed information on irradiation geometries are needed in order to render meaningful information from dose label indicators. (author)

  17. Process control and dosimetry applied to establish a relation between reference dose measurements and actual dose distribution

    International Nuclear Information System (INIS)

    Ehlerman, D.A.E.

    2001-01-01

    The availability of the first commercial dose level indicator prompted attempts to verify radiation absorbed dose to items under quarantine control (e.g. for insect disinfestation) by some indicator attached to these items. Samples of the new commercial dose level indicators were tested for their metrological properties using gamma and electron irradiation. The devices are suitable for the intended purpose and the subjective judgement whether the threshold dose was surpassed is possible in a reliable manner. The subjective judgements are completely backed by the instrumental results. Consequently, a prototype reader was developed; first tests were successful. The value of dose level indicators and the implications of its use for food or quarantine inspection depends on a link between dose measured (indicated) at the position of such indicator and the characteristic parameters of the frequency distribution of dose throughout the product load i.e. a box or a container or a whole batch of multiple units. Therefore, studies into variability and statistical properties of dose distributions obtained under a range of commercial situations were undertaken. Gamma processing at a commercial multipurpose contract irradiator, electron processing and bremsstrahlung applications at a largescale research facility were included; products were apples, potatoes, wheat, maize, pistachio. Studies revealed that still more detailed information on irradiation geometries are needed in order to render meaningful information from dose label indicators. (author)

  18. Measurement of the surface charge accumulation using anodic aluminum oxide(AAO) structure in an inductively coupled plasma

    Science.gov (United States)

    Park, Ji-Hwan; Oh, Seung-Ju; Lee, Hyo-Chang; Kim, Yu-Sin; Kim, Young-Cheol; Kim, June Young; Ha, Chang-Seoung; Kwon, Soon-Ho; Lee, Jung-Joong; Chung, Chin-Wook

    2014-10-01

    As the critical dimension of the nano-device shrinks, an undesired etch profile occurs during plasma etch process. One of the reasons is the local electric field due to the surface charge accumulation. To demonstrate the surface charge accumulation, an anodic aluminum oxide (AAO) membrane which has high aspect ratio is used. The potential difference between top electrode and bottom electrode in an anodic aluminum oxide contact structure is measured during inductively coupled plasma exposure. The voltage difference is changed with external discharge conditions, such as gas pressure, input power, and gas species and the result is analyzed with the measured plasma parameters.

  19. Assessment of dose measurement uncertainty using RisøScan

    DEFF Research Database (Denmark)

    Helt-Hansen, J.; Miller, A.

    2006-01-01

    The dose measurement uncertainty of the dosimeter system RisoScan, office scanner and Riso B3 dosimeters has been assessed by comparison with spectrophotometer measurements of the same dosimeters. The reproducibility and the combined uncertainty were found to be approximately 2% and 4%, respectiv......%, respectively, at one standard deviation. The subroutine in RisoScan for electron energy measurement is shown to give results that are equivalent to the measurements with a scanning spectrophotometer. (c) 2006 Elsevier Ltd. All rights reserved....

  20. Measurement of neutron and gamma absorbed doses in phantoms exposed to mixed fields

    International Nuclear Information System (INIS)

    Beraud-Sudreau, E.; Lemaire, G.; Maas, J.

    1985-01-01

    In order to study the dosimetric characteristics of PIN junctions, the absorbed doses measured by junctions and FLi7 in air and water phantoms were compared with the doses measured by classical neutron dosimetry in mixed fields. The validity of the experimental responses of PIN junctions being thus checked and established, neutron and gamma dose distributions in tissue equivalent plastic phantoms (plastinaut) and mammals (piglets) were evaluated as well as the absorbed dose distributions in the pig bone-marrow producing areas. By using correlatively a Monte-Carlo calculation method and applying some simplifying assumptions, the absorbed doses were derived from the spectrum of SILENE's neutrons at various depths inside a cubic water phantom and the results were compared with some from the literature [fr

  1. Measurement and estimation of maximum skin dose to the patient for different interventional procedures

    International Nuclear Information System (INIS)

    Cheng Yuxi; Liu Lantao; Wei Kedao; Yu Peng; Yan Shulin; Li Tianchang

    2005-01-01

    Objective: To determine the dose distribution and maximum skin dose to the patient for four interventional procedures: coronary angiography (CA), hepatic angiography (HA), radiofrequency ablation (RF) and cerebral angiography (CAG), and to estimate the definitive effect of radiation on skin. Methods: Skin dose was measured using LiF: Mg, Cu, P TLD chips. A total of 9 measuring points were chosen on the back of the patient with two TLDs placed at each point, for CA, HA and RF interventional procedures, whereas two TLDs were placed on one point each at the postero-anterior (PA) and lateral side (LAT) respectively, during the CAG procedure. Results: The results revealed that the maximum skin dose to the patient was 1683.91 mGy for the HA procedure with a mean value of 607.29 mGy. The maximum skin dose at the PA point was 959.3 mGy for the CAG with a mean value of 418.79 mGy; While the maximum and the mean doses at the LAT point were 704 mGy and 191.52 mGy, respectively. For the RF procedure the maximum dose was 853.82 mGy and the mean was 219.67 mGy. For the CA procedure the maximum dose was 456.1 mGy and the mean was 227.63 mGy. Conclusion: All the measured dose values in this study are estimated ones which could not provide the accurate maximum value because it is difficult to measure using a great deal of TLDs. On the other hand, the small area of skin exposed to high dose could be missed as the distribution of the dose is successive. (authors)

  2. Environmental dose measurement with microprocessor based portable TLD reader

    International Nuclear Information System (INIS)

    Deme, S.; Apathy, I.; Feher, I.

    1996-01-01

    Application of TL method for environmental gamma-radiation dosimetry involves uncertainty caused by the dose collected during the transport from the point of annealing to the place of exposure and back to the place of evaluation. Should an accident occur read out is delayed due to the need to transport to a laboratory equipped with a TLD reader. A portable reader capable of reading out the TL dosemeter at the place of exposure ('in situ TLD reader') eliminates the above mentioned disadvantages. We have developed a microprocessor based portable TLD reader for monitoring environmental gamma-radiation doses and for on board reading out of doses on space stations. The first version of our portable, battery operated reader (named Pille - 'butterfly') was made at the beginning of the 80s. These devices used CaSO 4 bulb dosemeters and the evaluation technique was based on analogue timing circuits and analogue to digital conversion of the photomultiplier current with a read out precision of 1 μGy and a measuring range up to 10 Gy. The measured values were displayed and manually recorded. The version with an external power supply was used for space dosimetry as an onboard TLD reader

  3. Phenolic compounds apigenin, hesperidin and kaempferol reduce in vitro lipid accumulation in human adipocytes.

    Science.gov (United States)

    Gómez-Zorita, Saioa; Lasa, Arrate; Abendaño, Naiara; Fernández-Quintela, Alfredo; Mosqueda-Solís, Andrea; Garcia-Sobreviela, Maria Pilar; Arbonés-Mainar, Jose M; Portillo, Maria P

    2017-11-21

    Adipocytes derived from human mesenchymal stem cells (MSCs) are widely used to investigate adipogenesis. Taking into account both the novelty of these MSCs and the scarcity of studies focused on the effects of phenolic compounds, the aim of the present study was to analyze the effect of apigenin, hesperidin and kaempferol on pre-adipocyte and mature adipocytes derived from this type of cells. In addition, the expression of genes involved in TG accumulation was also measured. Pre-adipocytes were cultured from day 0 to day 8 and mature adipocytes for 48 h with the polyphenols at doses of 1, 10 and 25 µM. Apigenin did not show an anti-adipogenic action. Pre-adipocytes treated with hesperidin and kaempferol showed reduced TG content at the three experimental doses. Apigenin did not modify the expression of the main adipogenic genes (c/ebpβ, c/ebpα, pparγ and srebp1c), hesperidin inhibited genes involved in the three phases of adipogenesis (c/ebpβ, srebp1c and perilipin) and kaempferol reduced c/ebpβ. In mature adipocytes, the three polyphenols reduced TG accumulation at the dose of 25 µM, but not at lower doses. All compounds increased mRNA levels of atgl. Apigenin and hesperidin decreased fasn expression. The present study shows the anti-adipogenic effect and delipidating effects of apigenin, hesperidin and kaempferol in human adipocytes derived from hMSCs. While hesperidin blocks all the stages of adipogenesis, kaempferol only inhibits the early stage. Regarding mature adipocytes, the three compounds reduce TG accumulation by activating, at least in part, lipolysis, and in the case of hesperidin and apigenin, also by reducing lipogenesis. The present study shows for the first time the anti-adipogenic effect and delipidating effect of apigenin, hesperidin and kaempferol in human adipocytes derived from MSCs for the first time.

  4. Activity measurement and effective dose modelling of natural radionuclides in building material

    International Nuclear Information System (INIS)

    Maringer, F.J.; Baumgartner, A.; Rechberger, F.; Seidel, C.; Stietka, M.

    2013-01-01

    In this paper the assessment of natural radionuclides' activity concentration in building materials, calibration requirements and related indoor exposure dose models is presented. Particular attention is turned to specific improvements in low-level gamma-ray spectrometry to determine the activity concentration of necessary natural radionuclides in building materials with adequate measurement uncertainties. Different approaches for the modelling of the effective dose indoor due to external radiation resulted from natural radionuclides in building material and results of actual building material assessments are shown. - Highlights: • Dose models for indoor radiation exposure due to natural radionuclides in building materials. • Strategies and methods in radionuclide metrology, activity measurement and dose modelling. • Selection of appropriate parameters in radiation protection standards for building materials. • Scientific-based limitations of indoor exposure due to natural radionuclides in building materials

  5. The use of polymer gel dosimetry to measure dose distribution around metallic implants

    International Nuclear Information System (INIS)

    Nagahata, Tomomasa; Yamaguchi, Hajime; Monzen, Hajime; Nishimura, Yasumasa

    2014-01-01

    A semi-solid polymer dosimetry system using agar was developed to measure the dose distribution close to metallic implants. Dosimetry of heterogeneous fields where electron density markedly varies is often problematic. This prompted us to develop a polymer gel dosimetry technique using agar to measure the dose distribution near substance boundaries. Varying the concentration of an oxygen scavenger (tetra-hydroxymethyl phosphonium chloride) showed the absorbed dose and transverse relaxation rate of the magnetic resonance signal to be linear between 3 and 12 Gy. Although a change in the dosimeter due to oxidization was observed in room air after 24 hours, no such effects were observed in the first 4 hours. The dose distribution around the metal implants was measured using agar dosimetry. The metals tested were a lead rod, a titanium hip joint, and a metallic stent. A maximum 30% dose increase was observed near the lead rod, but only a 3% increase in the absorbed dose was noted near the surface of the titanium hip joint and metallic stent. Semi-solid polymer dosimetry using agar thus appears to be a useful method for dosimetry around metallic substances. (author)

  6. [The use of polymer gel dosimetry to measure dose distribution around metallic implants].

    Science.gov (United States)

    Nagahata, Tomomasa; Yamaguchi, Hajime; Monzen, Hajime; Nishimura, Yasumasa

    2014-10-01

    A semi-solid polymer dosimetry system using agar was developed to measure the dose distribution close to metallic implants. Dosimetry of heterogeneous fields where electron density markedly varies is often problematic. This prompted us to develop a polymer gel dosimetry technique using agar to measure the dose distribution near substance boundaries. Varying the concentration of an oxygen scavenger (tetra-hydroxymethyl phosphonium chloride) showed the absorbed dose and transverse relaxation rate of the magnetic resonance signal to be linear between 3 and 12 Gy. Although a change in the dosimeter due to oxidization was observed in room air after 24 hours, no such effects were observed in the first 4 hours. The dose distribution around the metal implants was measured using agar dosimetry. The metals tested were a lead rod, a titanium hip joint, and a metallic stent. A maximum 30% dose increase was observed near the lead rod, but only a 3% increase in the absorbed dose was noted near the surface of the titanium hip joint and metallic stent. Semi-solid polymer dosimetry using agar thus appears to be a useful method for dosimetry around metallic substances.

  7. Dose measurements in space by the Hungarian Pille TLD system

    International Nuclear Information System (INIS)

    Apathy, I.; Deme, S.; Feher, I.; Akatov, Y.A.; Reitz, G.; Arkhanguelski, V.V.

    2002-01-01

    Exposure of crew, equipment, and experiments to the ambient space radiation environment in low Earth orbit poses one of the most significant problems to long-term space habitation. Accurate dose measurement has become increasingly important during the assembly (extravehicular activity (EVA)) and operation of space stations such as on Space Station Mir. Passive integrating detector systems such as thermoluminescent dosemeters (TLDs) are commonly used for dosimetry mapping and personal dosimetry on space vehicles. The well-known advantages of passive detector systems are their independence of power supply, small dimensions, high sensitivity, good stability, wide measuring range, resistance to environmental effects, and relatively low cost. Nevertheless, they have the general disadvantage that for evaluation purposes they need a laboratory or large--in mass and power consumption--terrestrial equipment, and consequently they cannot provide time-resolved dose data during long-term space flights. KFKI Atomic Energy Research Institute (KFKI AEKI) has developed and manufactured a series of thermoluminescent dosemeter systems for measuring cosmic radiation doses in the 10 μGy to 10 Gy range, consisting of a set of bulb dosemeters and a compact, self-contained, TLD reader suitable for on-board evaluation of the dosemeters. By means of such a system, highly accurate measurements were carried out on board the Salyut-6, -7 and Mir Space Stations as well as on the Space Shuttle. A detailed description of the system is given and the comprehensive results of these measurements are summarised

  8. Measures associated with the dose limitation system at the TVO Power Company

    International Nuclear Information System (INIS)

    Ruuskanen, A.T.; Sundell, R.O.

    1982-01-01

    The paper discusses radiation protection practices at the TVO Power Company, which owns and operates two BWR units of Asea-Atom design at Olkiluoto, Finland. The installed electric power of each unit is 660MW. The full power operation of TVO I and TVO II began in 1979 and 1980, respectively. The dose limitation system calls for an organization which is responsible for radiation protection. This organization at the plant site is described. To limit doses a good knowledge of the work activities which cause doses is needed. There is a very up-to-date microprocessor-based work dosimetry system at the TVO power plant. The system provides a practicable means of measuring personal doses from various work activities. It also makes the allocation of radiation protection measures possible. The system and experience in applying it are discussed. The dose limitation system presupposes the realization of the optimization principle. The practice applied at TVO in order to limit internal contamination is presented. Owing to this practice, workers' internal doses have remained at a considerably low level. The paper discusses the ALARA values of different kinds of respiratory equipment. These values, which vary from 2x10 4 to 1x10 6 FIM/man.Sv (1 FIM=approx. US$ 0.22), can be used in the evaluation of different measures in avoiding internal doses. The operating policy of movable lead shields is presented. The ALARA value of this activity is evaluated to be about 5x10 4 FIM/man.Sv and on that basis it can be concluded that the use of movable lead shields is very efficient. The dose statistics for TVO's plant are presented. The doses have been less than 0.001 man.Sv/MW.a. Although the dose statistics for TVO are very good it is not realistic to consider solely the optimization aspect of radiation protection. The costs must also be kept in mind; these are presented in the paper. Problems in assessing the level of radiation protection practices on an annual basis are briefly discussed

  9. Measurement of californium-252 gamma photons depth dose distribution in tissue equivalent material. Vol. 4

    Energy Technology Data Exchange (ETDEWEB)

    Fadel, M A; El-Fiki, M A; Eissa, H M; Abdel-Hafez, A; Naguib, S H [National Institute of Standards, Cairo (Egypt)

    1996-03-01

    Phantom of tissue equivalent material with and without bone was used measuring depth dose distribution of gamma-rays from californium-252 source. The source was positioned at center of perspex walled phantom. Depth dose measurements were recorded for X, Y and Z planes at different distances from source. TLD 700 was used for measuring the dose distribution. Results indicate that implantation of bone in tissue equivalent medium cause changes in the gamma depth dose distribution which varies according to variation in bone geometry. 9 figs.

  10. A unique experiment. Measurement of radiation doses at Vinca

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1960-07-15

    For the first time in the history of the peaceful applications of atomic energy, an experiment was conducted to determine the exact levels of radiation exposure resulting from a reactor incident. The experiment was made at Vinca, Yugoslavia, wherein October 1958 six persons had been subjected to high doses of neutron and gamma radiation during a brief uncontrolled run of a zero-power reactor. One of them died but the other five were successfully treated at the Curie Hospital in Paris. In the case of four of them, the treatment involved the grafting of healthy bone marrow to counteract the effects of radiation on blood-forming tissues. It was recognized that if the effects produced on the irradiated persons could be related to the exact doses of radiation they had received, it would be possible to gain immensely valuable knowledge about the biological consequences of acute and high level radiation exposure on a quantitative basis. It was suggested to the Yugoslav authorities that a dosimetry experiment be conducted at Vinca. The most accurate modern techniques of dosimetry developed at the Oak Ridge National Laboratory were employed during the experiment. Simultaneous measurements of the neutron and gamma doses were made at points where the people had been located. At these points the effects of the radiation on the salt solution in the phantoms were studied. In particular, the energy distribution of the radiation was investigated.It was the ratio between the various components of the radiation that was of special interest in these measurements because this ratio itself would help in determining the exact doses. The dose of one of the components, viz. slow neutrons, had already been determined during the treatment of the patients. If the ratio of the components could be ascertained, the doses of the fast neutrons and gamma rays could also be established because the ratio would not be affected by the power level at which the reactor was operated

  11. Occupational exposure of phosphate mine workers: airborne radioactivity measurements and dose assessment

    International Nuclear Information System (INIS)

    Khater, Ashraf E.; Hussein, M.A.; Hussein, Mohamed I.

    2004-01-01

    Under the Egyptian program for radiation safety and control, airborne radioactivity measurements and radiological dose assessment were conducted in some phosphate and uranium mines. Abu-Tartor mine is one of the biggest underground phosphate mines in Egypt. Airborne radioactivity, radon ( 222 Rn) and its short-lived decay products (progenies) and thoron ( 220 Rn), were measured in selected locations along the mine. The environmental gamma and workers dose equivalent rate (mSv/y) were measured inside and outside the mine using thermo-luminescence dosimeters (TLD). The results were presented and discussed. The calculated annual effective dose due to airborne radioactivity is the main source of occupational exposure and exceeding the maximum recommended level by ICRP-60 inside the mine tunnels. A number of recommendations are suggested to control the occupational exposures

  12. Measurement of off-axis and peripheral skin dose using radiochromic film

    International Nuclear Information System (INIS)

    Butson, Martin J.; Yu, P.K.N.; Metcalfe, P.E.

    1998-01-01

    A radiotherapy skin dose profile can be obtained with radiochromic film. The central axis skin dose relative to D max for a 10x10cm 2 field size was found to be 22%, 17% and 15.5% for 6 MV, 10 MV and 18 MV photon beams. Peripheral dose increased with increasing field size. At 10 MV the skin dose 2 cm outside the geometric field edge was measured as 6%, 10% and 17% for 10x10cm 2 , 20x20cm 2 and 30x30cm 2 field sizes respectively. Off-axis skin dose decreased as distance increased from central axis for fields with Perspex block trays. For a 20x20cm 2 field, an approximately 5-8% drop in percentage skin dose was observed from central axis to the beam edge. (author)

  13. MO-AB-BRA-03: Calorimetry-Based Absorbed Dose to Water Measurements Using Interferometry

    Energy Technology Data Exchange (ETDEWEB)

    Flores-Martinez, E; Malin, M; DeWerd, L [University of WI-Madison/ADCL, Madison, WI (United States)

    2015-06-15

    Purpose: Interferometry-based calorimetry is a novel technique to measure radiation-induced temperature changes allowing the measurement of absorbed dose to water (ADW). There are no mechanical components in the field. This technique also has the possibility of obtaining 2D dose distributions. The goal of this investigation is to calorimetrically-measure doses between 2.5 and 5 Gy over a single projection in a photon beam using interferometry and compare the results with doses calculated using the TG-51 linac calibration. Methods: ADW was determined by measuring radiation-induced phase shifts (PSs) of light passing through water irradiated with a 6 MV photon beam. A 9×9×9 cm{sup 3} glass phantom filled with water and placed in an arm of a Michelson interferometer was irradiated with 300, 400, 500 and 600 monitor units. The whole system was thermally insulated to achieve sufficient passive temperature control. The depth of measurement was 4.5 cm with a field size of 7×7 cm{sup 2}. The intensity of the fringe pattern was monitored with a photodiode and used to calculate the time-dependent PS curve. Data was acquired 60 s before and after the irradiation. The radiation-induced PS was calculated by taking the difference in the pre- and post-irradiation drifts extrapolated to the midpoint of the irradiation. Results were compared to computed doses. Results: Average comparison of calculated ADW values with interferometry-measured values showed an agreement to within 9.5%. k=1 uncertainties were 4.3% for calculations and 14.7% for measurements. The dominant source of uncertainty for the measurements was a temperature drift of about 30 µK/s caused by heat conduction from the interferometer’s surroundings. Conclusion: This work presented the first absolute ADW measurements using interferometry in the dose range of linac-based radiotherapy. Future work to improve measurements’ reproducibility includes the implementation of active thermal control techniques.

  14. Phase space determination from measured dose data for intraoperative electron radiation therapy.

    Science.gov (United States)

    Herranz, E; Herraiz, J L; Ibáñez, P; Pérez-Liva, M; Puebla, R; Cal-González, J; Guerra, P; Rodríguez, R; Illana, C; Udías, J M

    2015-01-07

    A procedure to characterize beams of a medical linear accelerator for their use in Monte Carlo (MC) dose calculations for intraoperative electron radiation therapy (IOERT) is presented. The procedure relies on dose measurements in homogeneous media as input, avoiding the need for detailed simulations of the accelerator head. An iterative algorithm (EM-ML) has been employed to extract the relevant details of the phase space (PHSP) of the particles coming from the accelerator, such as energy spectra, spatial distribution and angle of emission of particles. The algorithm can use pre-computed dose volumes in water and/or air, so that the machine-specific tuning with actual data can be performed in a few minutes. To test the procedure, MC simulations of a linear accelerator with typical IOERT applicators and energies, have been performed and taken as reference. A solution PHSP derived from the dose produced by the simulated accelerator has been compared to the reference PHSP. Further, dose delivered by the simulated accelerator for setups not included in the fit of the PHSP were compared to the ones derived from the solution PHSP. The results show that it is possible to derive from dose measurements PHSP accurate for IOERT MC dose estimations.

  15. 128 slice computed tomography dose profile measurement using thermoluminescent dosimeter

    International Nuclear Information System (INIS)

    Salehhon, N; Hashim, S; Karim, M K A; Ang, W C; Musa, Y; Bahruddin, N A

    2017-01-01

    The increasing use of computed tomography (CT) in clinical practice marks the needs to understand the dose descriptor and dose profile. The purposes of the current study were to determine the CT dose index free-in-air (CTDI air ) in 128 slice CT scanner and to evaluate the single scan dose profile (SSDP). Thermoluminescent dosimeters (TLD-100) were used to measure the dose profile of the scanner. There were three sets of CT protocols where the tube potential (kV) setting was manipulated for each protocol while the rest of parameters were kept constant. These protocols were based from routine CT abdominal examinations for male adult abdomen. It was found that the increase of kV settings made the values of CTDI air increased as well. When the kV setting was changed from 80 kV to 120 kV and from 120 kV to 140 kV, the CTDI air values were increased as much as 147.9% and 53.9% respectively. The highest kV setting (140 kV) led to the highest CTDI air value (13.585 mGy). The p -value of less than 0.05 indicated that the results were statistically different. The SSDP showed that when the kV settings were varied, the peak sharpness and height of Gaussian function profiles were affected. The full width at half maximum (FWHM) of dose profiles for all protocols were coincided with the nominal beam width set for the measurements. The findings of the study revealed much information on the characterization and performance of 128 slice CT scanner. (paper)

  16. Measurement of depth-dose distributions by means of the LiF-fluoroplastic thermoluminescent detectors

    International Nuclear Information System (INIS)

    Shaks, A.I.; Uryaev, I.A.; Trifonov, V.A.; Reshetnikova, L.V.

    1977-01-01

    Depth-dose distributions have been studied by means of thin-layer thermoluminescent detectors LiF-fluoroplast (8 mg/cm 2 ). Dosimetric characteristics of the detectors are described. They are: tissue-equivalence, dependence of sensitivity on the dose, dose rate and angle of incidence of radiation, and time-dependent storage, of the total light absorbed. Comparison of the results obtained with the measurements taken with an extrapolation chamber has demonstrated the possibility of measuring the depth-dose distributions by means of LiF-fluoroplast detectors

  17. SU-E-T-481: In Vivo and Post Mortem Animal Irradiation: Measured Vs. Calculated Doses

    Energy Technology Data Exchange (ETDEWEB)

    Heintz, P [Univ New Mexico Radiology Dept., Albuquerque, NM (United States); Heintz, B [Texas Oncology, PA, Southlake, TX (United States); Sandoval, D [University of New Mexico, Albuquerque, NM (United States); Weber, W; Melo, D; Guilmette, R [Lovelace Respiratory Research Institute, Albuquerque, NM (United States)

    2015-06-15

    Purpose: Computerized radiation therapy treatment planning is performed on almost all patients today. However it is seldom used for laboratory irradiations. The first objective is to assess whether modern radiation therapy treatment planning (RTP) systems accurately predict the subject dose by comparing in vivo and decedent dose measurements to calculated doses. The other objective is determine the importance of using a RTP system for laboratory irradiations. Methods: 5 MOSFET radiation dosimeters were placed enterically in each subject (2 sedated Rhesus Macaques) to measure the absorbed dose at 5 levels (carina, lung, heart, liver and rectum) during whole body irradiation. The subjects were treated with large opposed lateral fields and extended distances to cover the entire subject using a Varian 600C linac. CT simulation was performed ante-mortem (AM) and post-mortem (PM). To compare AM and PM doses, calculation points were placed at the location of each dosimeter in the treatment plan. The measured results were compared to the results using Varian Eclipse and Prowess Panther RTP systems. Results: The Varian and Prowess treatment planning system agreed to within in +1.5% for both subjects. However there were significant differences between the measured and calculated doses. For both animals the calculated central axis dose was higher than prescribed by 3–5%. This was caused in part by inaccurate measurement of animal thickness at the time of irradiation. For one subject the doses ranged from 4% to 7% high and the other subject the doses ranged 7% to 14% high when compared to the RTP doses. Conclusions: Our results suggest that using proper CT RTP system can more accurately deliver the prescribed dose to laboratory subjects. It also shows that there is significant dose variation in such subjects when inhomogeneities are not considered in the planning process.

  18. Accredited dose measurements for validation of radiation sterilized products

    DEFF Research Database (Denmark)

    Miller, A.

    1993-01-01

    for control of radiation sterilization. The accredited services include: 1. 1. Irradiation of dosimeters and test samples with cobalt-60 gamma rays. 2. 2. Irradiation of dosimeters and test samples with 10 MeV electrons. 3. 3. Issue of and measurement with calibrated dosimeters. 4. 4. Measurement...... of the dosimetric parameters of an irradiation facility. 5. 5. Measurement of absorbed dose distribution in irradiated products. The paper describes these services and the procedures necessary for their execution....

  19. SU-E-T-628: Effect of Dose Rate and Leakage Correction for Dosimetric Leaf Gap Measurement

    Energy Technology Data Exchange (ETDEWEB)

    Feng, W [New York Presbyterian Hospital, Tenafly, NJ (United States); Chu, A [Yale New Haven Hospital, New Haven, CT (United States); Chi, Y [Winter Park Cancer Center, Winter Park, FL (United States); Hu, J [Wayne State University, Detroit, MI (United States)

    2014-06-15

    Purpose: To study the dose rate response of Mapcheck and quantify/correct dose rate/leakage effect on IMRT QA. Evaluate the dose rate/leakage effect on dosimetric leaf gap (DLG) measurement. Methods: Varian Truebeam Linac with HD120 MLC was used for all measurement, it is capable to adjust dose rate from 600MU/min to 5MU/min. Fluke Advanced Therapy Doisemter and PTW 30013 Farmer chamber for chamber measurement; SunNuclear Mapcheck2 with 5cm total buildup for diode measurement. DLG was measured with both chamber and diode.Diode response was measured by varies dose rate, while fixed mapcheck setup and total MU. MLC Leakage was measured with both chamber and diode. Mapcheck measurement was saved as movie file (mcm file), which include measurement updated every 50mSec. The difference between intervals can be converted to dose and dose rate and leakage response correction can be applied to them. Results: DLG measurement results with chamber and diode were showed as follows, the DLG value is 0.36 vs. 0.24mm respectively. Diode dose rate response drops from 100% at 600MU/min to 95.5% at 5MU/min as follows. MLC Leakage measured with diode is 1.021%, which is 9% smaller than 1.112% from chamber measurement. By apply the dose rate and leakage correction, the residue error reduced 2/3. Conclusions: Diode has lower response at lower dose rate, as low as 4.5% for 5MU/min; diode has lower energy response for low energy too, 5% lower for Co-60 than 6MV. It partially explains the leakage difference of 9% between chamber and diode. Lower DLG with diode is because of the lower response at narrower gap, in Eclipse however DLG need to increase to makeup lower response, which is over correction for chamber though. Correction can reduce error by 2/3, the rest 1/3 can be corrected by scatter effect, which is under study.

  20. Measurements of eye lens doses in interventional radiology and cardiology: Final results of the ORAMED project

    International Nuclear Information System (INIS)

    Vanhavere, F.; Carinou, E.; Domienik, J.; Donadille, L.; Ginjaume, M.; Gualdrini, G.; Koukorava, C.; Krim, S.; Nikodemova, D.; Ruiz-Lopez, N.; Sans-Merce, M.; Struelens, L.

    2011-01-01

    Within the ORAMED project (Optimization of Radiation Protection of Medical Staff) a coordinated measurement program for occupationally exposed medical staff was performed in different hospitals in Europe ( (www.oramed-fp7.eu)). The main objective was to obtain a set of standardized data on extremity and eye lens doses for staff involved in interventional radiology and cardiology and to optimize radiation protection. Special attention was given to the measurement of the doses to the eye lenses. In this paper an overview will be given of the measured eye lens doses and the main influence factors for these doses. The measured eye lens doses are extrapolated to annual doses. The extrapolations showed that monitoring of the eye lens should be performed on routine basis.

  1. Radiation dose to children in diagnostic radiology. Measurements and methods for clinical optimisation studies

    Energy Technology Data Exchange (ETDEWEB)

    Almen, A J

    1995-09-01

    A method for estimating mean absorbed dose to different organs and tissues was developed for paediatric patients undergoing X-ray investigations. The absorbed dose distribution in water was measured for the specific X-ray beam used. Clinical images were studied to determine X-ray beam positions and field sizes. Size and position of organs in the patient were estimated using ORNL phantoms and complementary clinical information. Conversion factors between the mean absorbed dose to various organs and entrance surface dose for five different body sizes were calculated. Direct measurements on patients estimating entrance surface dose and energy imparted for common X-ray investigations were performed. The examination technique for a number of paediatric X-ray investigations used in 19 Swedish hospitals was studied. For a simulated pelvis investigation of a 1-year old child the entrance surface dose was measured and image quality was estimated using a contrast-detail phantom. Mean absorbed doses to organs and tissues in urography, lung, pelvis, thoracic spine, lumbar spine and scoliosis investigations was calculated. Calculations of effective dose were supplemented with risk calculations for special organs e g the female breast. The work shows that the examination technique in paediatric radiology is not yet optimised, and that the non-optimised procedures contribute to a considerable variation in radiation dose. In order to optimise paediatric radiology there is a need for more standardised methods in patient dosimetry. It is especially important to relate measured quantities to the size of the patient, using e g the patient weight and length. 91 refs, 17 figs, 8 tabs.

  2. Radiation dose to children in diagnostic radiology. Measurements and methods for clinical optimisation studies

    International Nuclear Information System (INIS)

    Almen, A.J.

    1995-09-01

    A method for estimating mean absorbed dose to different organs and tissues was developed for paediatric patients undergoing X-ray investigations. The absorbed dose distribution in water was measured for the specific X-ray beam used. Clinical images were studied to determine X-ray beam positions and field sizes. Size and position of organs in the patient were estimated using ORNL phantoms and complementary clinical information. Conversion factors between the mean absorbed dose to various organs and entrance surface dose for five different body sizes were calculated. Direct measurements on patients estimating entrance surface dose and energy imparted for common X-ray investigations were performed. The examination technique for a number of paediatric X-ray investigations used in 19 Swedish hospitals was studied. For a simulated pelvis investigation of a 1-year old child the entrance surface dose was measured and image quality was estimated using a contrast-detail phantom. Mean absorbed doses to organs and tissues in urography, lung, pelvis, thoracic spine, lumbar spine and scoliosis investigations was calculated. Calculations of effective dose were supplemented with risk calculations for special organs e g the female breast. The work shows that the examination technique in paediatric radiology is not yet optimised, and that the non-optimised procedures contribute to a considerable variation in radiation dose. In order to optimise paediatric radiology there is a need for more standardised methods in patient dosimetry. It is especially important to relate measured quantities to the size of the patient, using e g the patient weight and length. 91 refs, 17 figs, 8 tabs

  3. Spherical ionization chamber of 14 liter for precise measurement of environmental radiation dose rate

    International Nuclear Information System (INIS)

    Nagaoka, Toshi; Saito, Kimiaki; Moriuchi, Shigeru

    1991-05-01

    A spherical ionization chamber of 14 liter filled with 1 atm. nitrogen gas was arranged aiming at precise measurement of dose rate due to environmental gamma rays and cosmic rays. Ionization current-dose rate conversion factor for this ionization chamber was derived from careful consideration taking into account the attenuation by chamber wall, ionization current due to alpha particles and so on. Experiments at calibrated gamma ray fields and intercomparison with NaI(Tl) scintillation detector were also performed, which confirmed this ionization chamber using the conversion factor can measure the dose rate with an error of only a few percent. This ionization chamber will be used for measurement of environmental gamma ray and cosmic ray dose rate. (author)

  4. Introduction: Issues Related to Dose Units and Damage Correlation

    International Nuclear Information System (INIS)

    Stoller, Roger E.

    2012-01-01

    The observable effects of irradiation on material properties are complex and each such property changed depends sensitively on a range of irradiation and material parameters. This works against development of a universal exposure parameter. The irradiation dose to the material (both ionizing and displacement dose) can be calculated with good accuracy as long as the relevant reaction cross sections are known and implemented in the codes used. This suggests that a focus on dose calculations is warranted. When assessing damage correlation parameters, it is important to determine the appropriate dose parameter first. Then a clear distinction between damage formation and damage accumulation needs to be kept in mind. The dose unit is most helpful for estimating the primary damage generation, e.g. how damage energy is used to estimate atomic displacements. However, damage accumulation requires longer times and involves kinetic and thermodynamic processes that cannot be accounted for in a dose or primary damage unit. The adequacy of the primary damage formulations can be assessed through their use in mean field reaction rate theory or kinetic Monte Carlo microstructural evolution models to predict damage accumulation. The results of these models can be directly compared with experimental observations. (author)

  5. Dual-peak dose measurement for radiochromic films by a newly developed spectral microdensitometer

    International Nuclear Information System (INIS)

    Lee, K.Y.; Fung, K.K.L.; Kwok, C.S.

    2005-01-01

    Radiochromic film (RCF) dosimetry is usually based on densitometric methods which use an analyzing light source of a fixed or a broad spectrum of wavelengths. These methods have not exploited the sensitivity of the dose response of the RCF otherwise attainable by using a light source with wavelengths peaked at the two absorption peaks in the absorption spectrum of the RCF. A new algorithm of dual-peak dose measurement for the RCF has been proposed in this paper to make use of these dual absorption peaks to achieve the maximum attainable sensitivity. This technique relies on the measurement of the transmittance of the RCF at the wavelength of the major and minor absorption peaks, respectively. The dual-peak dose measurement is accomplished with the aid of a novel spectral microdensitometer developed in our Institute. The microdensitometer utilizes a monochromator to provide a light source of which the wavelength can be matched precisely to the wavelength of the absorption peaks of the RCF. The doses obtained at these wavelengths are fed into a weighted objective function and an optimum dose is searched by minimizing the objective function to give the best estimate of the dose deposited on the film. An initial test shows that there is a good agreement between the estimated and actual dose deposited; and the maximum discrepancy was found to be less than 1%

  6. Global real-time dose measurements using the Automated Radiation Measurements for Aerospace Safety (ARMAS) system

    Science.gov (United States)

    Tobiska, W. Kent; Bouwer, D.; Smart, D.; Shea, M.; Bailey, J.; Didkovsky, L.; Judge, K.; Garrett, H.; Atwell, W.; Gersey, B.; Wilkins, R.; Rice, D.; Schunk, R.; Bell, D.; Mertens, C.; Xu, X.; Wiltberger, M.; Wiley, S.; Teets, E.; Jones, B.; Hong, S.; Yoon, K.

    2016-11-01

    The Automated Radiation Measurements for Aerospace Safety (ARMAS) program has successfully deployed a fleet of six instruments measuring the ambient radiation environment at commercial aircraft altitudes. ARMAS transmits real-time data to the ground and provides quality, tissue-relevant ambient dose equivalent rates with 5 min latency for dose rates on 213 flights up to 17.3 km (56,700 ft). We show five cases from different aircraft; the source particles are dominated by galactic cosmic rays but include particle fluxes for minor radiation periods and geomagnetically disturbed conditions. The measurements from 2013 to 2016 do not cover a period of time to quantify galactic cosmic rays' dependence on solar cycle variation and their effect on aviation radiation. However, we report on small radiation "clouds" in specific magnetic latitude regions and note that active geomagnetic, variable space weather conditions may sufficiently modify the magnetospheric magnetic field that can enhance the radiation environment, particularly at high altitudes and middle to high latitudes. When there is no significant space weather, high-latitude flights produce a dose rate analogous to a chest X-ray every 12.5 h, every 25 h for midlatitudes, and every 100 h for equatorial latitudes at typical commercial flight altitudes of 37,000 ft ( 11 km). The dose rate doubles every 2 km altitude increase, suggesting a radiation event management strategy for pilots or air traffic control; i.e., where event-driven radiation regions can be identified, they can be treated like volcanic ash clouds to achieve radiation safety goals with slightly lower flight altitudes or more equatorial flight paths.

  7. Measurement of Skin Dose from Using the Treatment Immobilization Devices

    International Nuclear Information System (INIS)

    Je, Jae Yong; Park, Chul Woo; Noh, Kyung Suk

    2009-01-01

    The research was about the relation between the dorsal side dose measured by using the phantom body (Alderson Rando Phantom) and factors like contacted material of the patients, the size of the field, angle of incidence. Compared with mylar (tennis racket), the dose on 10 x 10 cm 2 field size of cotton was increased by 2% and by 8% in the case of breast board. In the case of 15 x 15 cm 2 field size, the dose was increased by 6% compared with 10 x 10 cm 2 size. The field size of 20 x 20 cm 2 resulted in 10% increase of dose, while 5 x 5 cm 2 produced 13% decrease. Compared with incident angle 0 degree, the cases for the incident angle 5 degrees had 0.4% less dose for breast board, 0.5% for tennis racket, 1.1% for cotton. The cases for the incident angle 10 degrees had 1.5% less dose for breast board, 1.9% for tennis racket, 2.6% for cotton. For the incident angle 15 degrees, breast board, tennis racket, cotton caused decrease of dose by 3.9%, 2.6%, 3.86% respectively. Resultantly carbon material can cause more skin dose in treatment field. By the results of this study, we recommend that one should avoid the contact between the carbon material and skin.

  8. Measurement of beta emitting radionuclides in dose calibrators routinely used in nuclear medicine departments

    International Nuclear Information System (INIS)

    Tastan, S.; Soylu, A.; Kucuk, O.; Ibis, E.

    2004-01-01

    Full text: Radionuclides for diagnostics purposes like Tc-99m, Tl-201, Ga-67 and In-111 are measured by using ionization type of dose calibrators. Therapeutic radionuclides, which emit both beta and gamma rays are detected by the same type of dose calibrators. Other therapeutic products like Y-90, P-32 and Sr-89 are pure beta emitters and they are gaining wider utility because various new therapy radiopharmaceuticals are being developed. The type of container material, like glass or plastic, may seriously affect radioactivity measurement due to attenuation, Since it is crucial to give the exact amount of radioactivity to the patient for therapy purposes, dedicated dose calibrators are specially manufactured for the measurement of these radionuclides. But these measuring systems are not widely available in nuclear medicine centers where therapy is applied to the patient. It is a known fact that dose calibrators routinely used in nuclear medicine departments can be calibrated for vials and syringes using standard sources of the same radioisotope. The method of calibration of Y-90 measurement for two ionization chamber dose calibrators available in the institute will be summarized in this presentation

  9. Measurement of beta emitting radionuclides in dose calibrators routinely used in nuclear medicine departments

    International Nuclear Information System (INIS)

    Tastan, S.; Soylu, A.; Kucuk, O.; Ibis, E.

    2004-01-01

    Radionuclides for diagnostics purposes like Tc-99m, Tl-201, Ga-67 and In-111 are measured by using ionization type of dose calibrators. Therapeutic radionuclides, which emit both beta and gamma rays are detected by the same type of dose calibrators. Other therapeutic products like Y-90, P-32 and Sr-89 are pure beta emitters and they are gaining wider utility because various new therapy radiopharmaceuticals are being developed. The type of container material, like glass or plastic, may seriously affect radioactivity measurement due to attenuation, Since it is crucial to give the exact amount of radioactivity to the patient for therapy purposes, dedicated dose calibrators are specially manufactured for the measurement of these radionuclides. But these measuring systems are not widely available in nuclear medicine centers where therapy is applied to the patient. It is a known fact that dose calibrators routinely used in nuclear medicine departments can be calibrated for vials and syringes using standard sources of the same radioisotope. The method of calibration of Y-90 measurement for two ionization chamber dose calibrators available in the institute will be summarized in this presentation. (author)

  10. Dose measurement techniques for high-energy photon and electron radiation

    International Nuclear Information System (INIS)

    Hohlfeld, K.; Roos, M.

    1992-08-01

    By law the Federal Institute of Physics and Technology (PTB) has been assigned the tasks of representing, preserving and passing on dose units. The analogous continuation of these tasks consists in improving, at the user level, dosimetry techniques in radiation therapy for the benefit of patients. The PTB had an essential share in working out the scientific foundations of dosimetry for high-energy radiation, and the corresponding DIN standards were established with the PTB playing a prominent part. The seminar aimed at presenting the measuring techniques fixed in the new DIN standard 6800 part 2 'Dose measurement techniques according to the probe method - ionization dosimetry', to discuss their physical background and practical implications resulting from them. (orig.) [de

  11. Measurements of the electron dose distribution near inhomogeneities using a plastic scintillation detector

    International Nuclear Information System (INIS)

    Wells, C.M.M.; Mackie, T.R.; Podgorsak, M.B.; Holmes, M.A.; Papanikolaou, N.; Reckwerdt, P.J.; Cygler, J.; Rogers, D.W.O.; Bielajew, A.F.; Schmidt, D.G.

    1994-01-01

    Accurate measurement of the electron dose distribution near an inhomogeneity is difficult with traditional dosimeters which themselves perturb the electron field. The authors tested the performance of a new high resolution, water-equivalent plastic scintillation detector which has ideal properties for this application. A plastic scintillation detector with a 1 mm diameter, 3 mm long cylindrical sensitive volume was used to measure the dose distributions behind standard benchmark inhomogeneities in water phantoms. The plastic scintillator material is more water equivalent than polystyrene in terms of its mass collision stopping power and mass scattering power. Measurements were performed for beams of electrons having initial energies of 6 and 18 MeV at depths from 0.2-4.2 cm behind the inhomogeneities. The detector reveals hot and cold spots behind heterogeneities at resolutions equivalent to typical film digitizer spot sizes. Plots of the dose distributions behind air, aluminum, lead, and formulations for cortical and inner bone-equivalent materials are presented. The plastic scintillation detector is suited for measuring the electron dose distribution near an inhomogeneity. 14 refs., 9 figs

  12. Comparison of two techniques for natural dose measurements

    International Nuclear Information System (INIS)

    Ekdal, E.; Ege, A.; Goekce, M.; Karali, T.; Derin, Z.

    2006-01-01

    In the study of luminescence dating, age of an archaeological sample is calculated by the ratio of total exposed dose to annual dose resulted from the environmental radioactivity. Determination of the annual dose level of an archaeological area is one of the most important parameter in calculating the archaeological age of the sample using luminescence techniques. Therefore, the knowledge of the concentrations of the natural radionuclides is important since naturally occurring radioactivity provides major contribution to the annual dose. The natural radioactivity is originated from natural radionuclides consisting mainly of 2 38U, 2 32Th and 4 0K isotopes together with their daughters in soils. In this study, annual dose level of the archaeological site was determined with two different methods: an indirect method that is determining the concentrations of the naturally occurring radioactive elements using gamma spectroscopy and a direct method that uses thermoluminescence dosimeters. Soil samples were collected from the Yesilova Hoeyuek archaeological site located in Izmir City at the Aegean Region of Turkey. The concentrations of the natural radioactivity ( 2 38U, 2 32Th and 4 0K) in soil samples were determined using 3 x 3 N aI (Tl) γ-ray spectrometry system. In direct method, Al 2 O 3 :C thermoluminescence dosimeters (TLD's) were used. These dosimeters were chosen because of their sensitivity and usability in dating studies. They were buried in same archaeological site, 30 cm depth from the soil surface for 30 days period. The luminescence intensity of Al 2 O 3 :C dosimeters was measured by a TLD reader and the dose level was calculated by the luminescence signals emitted by the dosimeters. The results obtained from natural radionuclides and Al 2 O 3 :C thermoluminescence dosimeters were compared and the source of the differences between two methods were discussed

  13. Radiation dose measurement for patients and staff during cardiac catheterization

    International Nuclear Information System (INIS)

    Joda, H. H. M.

    2009-07-01

    The primary objective of this study was to determine the patient and staff dose during cardiac catheterization procedures in Ahmed Gasim Hospital, Khartoum Bahry. A survey of patient and staff exposure was performed covered 2 Cath Lab units from 2 manufacturers. The measurements involved 50 operations. The medical staff was monitored using TLD chips (LiF: Mg, Cu, P). The main operator who was closer to the patient and the x-ray tube, was monitored at six positions (forehead, neck chest - over the lead apron, waist - under the lead apron, leg, and hand), while the exposure to the assistant was measured at two positions (chest - over the lead apron, and hand), where the technologist and the circulator were monitored at one position (chest - over the lead apron). patient exposure was measured using the DAP meter. The main operator and the rest of the staff received 0.14, 0.01 mSv/y respectively. The estimated patient dose rate was found to be 125 mGy/min which considered higher than the recommended DRL for the continuous high mode fluoroscopy used in interventional radiology (100 mGy/min). The study concluded to the fact that the main operator received relatively high dose which is a direct result to the poor radiation protection in the department. (Author)

  14. The current status of eye lens dose measurement in interventional cardiology personnel in Thailand.

    Science.gov (United States)

    Krisanachinda, Anchali; Srimahachota, Suphot; Matsubara, Kosuke

    2017-06-01

    Workers involved in interventional cardiology procedures receive high eye lens doses if radiation protection tools are not properly utilized. Currently, there is no suitable method for routine measurement of eye dose. In Thailand, the eye lens equivalent doses in terms of Hp(3) of the interventional cardiologists, nurses, and radiographers participating in interventional cardiology procedures have been measured at 12 centers since 2015 in the pilot study. The optically stimulated luminescence (OSL) dosimeter was used for measurement of the occupational exposure and the eye lens dose of 42 interventional cardiology personnel at King Chulalongkorn Memorial Hospital as one of the pilot centers. For all personnel, it is recommended that a first In Light OSL badge is placed at waist level and under the lead apron for determination of Hp(10); a second badge is placed at the collar for determination of Hp(0.07) and estimation of Hp(3). Nano Dots OSL dosimeter has been used as an eye lens dosimeter for 16 interventional cardiology personnel, both with and without lead-glass eyewear. The mean effective dose at the body, equivalent dose at the collar, and estimated eye lens dose were 0.801, 5.88, and 5.70 mSv per year, respectively. The mean eye lens dose measured by the Nano Dots dosimeter was 8.059 mSv per year on the left eye and 3.552 mSv per year on the right eye. Two of 16 interventional cardiologists received annual eye lens doses on the left side without lead glass that were higher than 20 mSv per year, the new eye lens dose limit as recommended by ICRP with the risk of eye lens opacity and cataract.

  15. Decontamination evaluation based on radioactivity measurement instead of air dose rate

    International Nuclear Information System (INIS)

    Shozugawa, Katsumi

    2013-01-01

    Air dose rate at 1 m above the ground comes from gamma radiations emitted from vast area ranging over several ten meters of the contaminated field from the counter. After showing the actual example of the difference between air dose rate data and Cs 137 distribution map made by using a shielded NaI-scintillation counter within and around a contaminated sinkhole (a ditch or trench) near Fukushima Daiichi Nuclear Power Plants, the author proposes to make a decontamination program according to the radioactivity distribution measurement instead of air dose rate measurement. Furthermore, he explains some problems arising from a point and plane radiation source, and also difficulties accompanied by movement of Cs 137 atoms in the soils according to the absorption characteristics of the existing minerals but these are also important to consider for performing an effective decontamination. (S. Ohno)

  16. Thyroid measurements of Iodine-125 workers

    International Nuclear Information System (INIS)

    Burns, P.A.; Peggie, J.R.

    1979-02-01

    The accumulation of 125 I in the thyroid presents real hazards to workers who use this radionuclide. Recent assessments of the maximum permissible thyroid burden for 125 I have tended to be lower than those previously adopted. Workers using 125 I may receive small doses to a film badge monitor from external radiation while accumulating significant doses to the thyroid from internal contamination. It is therefore necessary to perform some form of thyroid monitoring on such workers. In the past two years the Australian Radiation Laboratory has monitored 125 I workers from six different institutations in the Melbourne area to determine the activity of 125 I in their thyroids. Most of the levels monitored were less than one tenth of the most recently recommended thyroid burden of 400 nanocurie. The highest levels were measured in workers who actually perform iodinations. Workers who handle the iodinate generally had lower levels than those performing the iodinations. Only a very small number of the workers measured were below the detectable limit of the system indicating that even when low activities of 125 I are handled in relatively stable forms it is still possible to accumulate 125 I in the thyroid

  17. Experiment for dose measurement during beam killing at Indus-1 synchrotron radiation source

    International Nuclear Information System (INIS)

    Nayak, M.K.; Dev, Vipin; Haridas, G.; Thakkar, K.K.; Sarkar, P.K.; Sharma, D.N.

    2006-01-01

    Experimental measurement of radiation dose likely to be received by an occupational worker in the experimental hall of Indus-1 during accidental beam killing was carried out. Various accidental beam-killing scenarios were experimentally simulated for the measurement. The measurement was carried out using direct reading dosimeters. Result shows that in the event of accidental beam killing, dose likely to be received by an occupational worker outside the shield is negligible. (author)

  18. Comparison of methods for the measurement of radiation dose distributions in high dose rate (HDR) brachytherapy: Ge-doped optical fiber, EBT3 Gafchromic film, and PRESAGE® radiochromic plastic

    International Nuclear Information System (INIS)

    Palmer, A. L.; Di Pietro, P.; Alobaidli, S.; Issa, F.; Doran, S.; Bradley, D.; Nisbet, A.

    2013-01-01

    Purpose: Dose distribution measurement in clinical high dose rate (HDR) brachytherapy is challenging, because of the high dose gradients, large dose variations, and small scale, but it is essential to verify accurate treatment planning and treatment equipment performance. The authors compare and evaluate three dosimetry systems for potential use in brachytherapy dose distribution measurement: Ge-doped optical fibers, EBT3 Gafchromic film with multichannel analysis, and the radiochromic material PRESAGE ® with optical-CT readout. Methods: Ge-doped SiO 2 fibers with 6 μm active core and 5.0 mm length were sensitivity-batched and their thermoluminescent properties used via conventional heating and annealing cycles. EBT3 Gafchromic film of 30 μm active thickness was calibrated in three color channels using a nominal 6 MV linear accelerator. A 48-bit transmission scanner and advanced multichannel analysis method were utilized to derive dose measurements. Samples of the solid radiochromic polymer PRESAGE ® , 60 mm diameter and 100 mm height, were analyzed with a parallel beam optical CT scanner. Each dosimetry system was used to measure the dose as a function of radial distance from a Co-60 HDR source, with results compared to Monte Carlo TG-43 model data. Each system was then used to measure the dose distribution along one or more lines through typical clinical dose distributions for cervix brachytherapy, with results compared to treatment planning system (TPS) calculations. Purpose-designed test objects constructed of Solid Water and held within a full-scatter water tank were utilized. Results: All three dosimetry systems reproduced the general shape of the isolated source radial dose function and the TPS dose distribution. However, the dynamic range of EBT3 exceeded those of doped optical fibers and PRESAGE ® , and the latter two suffered from unacceptable noise and artifact. For the experimental conditions used in this study, the useful range from an isolated

  19. Comparison of methods for the measurement of radiation dose distributions in high dose rate (HDR) brachytherapy: Ge-doped optical fiber, EBT3 Gafchromic film, and PRESAGE® radiochromic plastic.

    Science.gov (United States)

    Palmer, A L; Di Pietro, P; Alobaidli, S; Issa, F; Doran, S; Bradley, D; Nisbet, A

    2013-06-01

    Dose distribution measurement in clinical high dose rate (HDR) brachytherapy is challenging, because of the high dose gradients, large dose variations, and small scale, but it is essential to verify accurate treatment planning and treatment equipment performance. The authors compare and evaluate three dosimetry systems for potential use in brachytherapy dose distribution measurement: Ge-doped optical fibers, EBT3 Gafchromic film with multichannel analysis, and the radiochromic material PRESAGE(®) with optical-CT readout. Ge-doped SiO2 fibers with 6 μm active core and 5.0 mm length were sensitivity-batched and their thermoluminescent properties used via conventional heating and annealing cycles. EBT3 Gafchromic film of 30 μm active thickness was calibrated in three color channels using a nominal 6 MV linear accelerator. A 48-bit transmission scanner and advanced multichannel analysis method were utilized to derive dose measurements. Samples of the solid radiochromic polymer PRESAGE(®), 60 mm diameter and 100 mm height, were analyzed with a parallel beam optical CT scanner. Each dosimetry system was used to measure the dose as a function of radial distance from a Co-60 HDR source, with results compared to Monte Carlo TG-43 model data. Each system was then used to measure the dose distribution along one or more lines through typical clinical dose distributions for cervix brachytherapy, with results compared to treatment planning system (TPS) calculations. Purpose-designed test objects constructed of Solid Water and held within a full-scatter water tank were utilized. All three dosimetry systems reproduced the general shape of the isolated source radial dose function and the TPS dose distribution. However, the dynamic range of EBT3 exceeded those of doped optical fibers and PRESAGE(®), and the latter two suffered from unacceptable noise and artifact. For the experimental conditions used in this study, the useful range from an isolated HDR source was 5-40 mm for

  20. Measurement of dose enhancement close to high atomic number media using optical fibre thermoluminescence dosimeters

    International Nuclear Information System (INIS)

    Alalawi, Amani I.; Hugtenburg, R.P.; Abdul Rahman, A.T.; Barry, M.A.; Nisbet, A.; Alzimami, Khalid S.; Bradley, D.A.

    2014-01-01

    Present interest concerns development of a system to measure photoelectron-enhanced dose close to a tissue interface using analogue gold-coated doped silica-fibre thermoluminescence detectors and an X-ray set operating at 250 kVp. Study is made of the dose enhancement factor for various thicknesses of gold; measurements at a total gold thickness of 160 nm (accounting for incident and exiting photons) produces a mean measured dose enhancement factor of 1.33±0.01 To verify results, simulations of the experimental setup have been performed. - Highlights: • Dose enhancement • Thermoluminescence dosimeter • Monte Carlo simulation

  1. Eye dose measurements using conventional and rare-earth screens during tomography of the para-nasal sinuses

    International Nuclear Information System (INIS)

    Eddleston, B.; Moores, B.M.; Walker, A.

    1977-01-01

    Eye dose measurements have been performed when using medium speed conventional and rare-earth screen-film combinations during tomography of the para-nasal sinuses. The measurements showed that using conventional intensifying screens with the A.P. view a total eye dose of about 20 rad may be given during an examination. This eye dose can be reduced by 98% using the P.A. position. If rare-earth screen/film combinations were employed the eye dose measured in the A.P. view was reduced by 75% of that obtained with conventional screens without detectable loss of image quality. A total eye dose reduction of about 99.5% was measured in the P.A. view with the rare-earth systems. (author)

  2. Cyp1a1(-/-) male mice: protection against high-dose TCDD-induced lethality and wasting syndrome, and resistance to intrahepatocyte lipid accumulation and uroporphyria

    International Nuclear Information System (INIS)

    Uno, Shigeyuki; Dalton, Timothy P.; Sinclair, Peter R.; Gorman, Nadia; Wang, Bin; Smith, Andrew G.; Miller, Marian L.; Shertzer, Howard G.; Nebert, Daniel W.

    2004-01-01

    To study liver toxicity and uroporphyrin (URO) accumulation and urinary excretion, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a potent ligand for the aryl hydrocarbon receptor (AHR), is often used as the prototype. In this study, we asked the question how important is the role of CYP1A1 in causing TCDD toxicity. Using a single large intraperitoneal dose of TCDD (200 μg/kg) and following the response over an 8-week period, we found this dose: (a) was lethal in less than 4 weeks to Cyp1a1(+/+) males but not to Cyp1a1(-/-) males or to females of either genotype; (b) caused a wasting syndrome in Cyp1a1(+/+) but not Cyp1a1(-/-) mice; (c) resulted in thymic atrophy, regardless of gender or genotype; (d) decreased spleen size and caused leukocytopenia in males but not females of either genotype; (e) caused hepatocyte hypertrophy in Cyp1a1(+/+) more so than in Cyp1a1(-/-) mice; (f) increased intrahepatocyte lipids and total liver fat content in Cyp1a1(+/+) more than Cyp1a1(-/-) males and females; and (g) caused uroporphyria in Cyp1a1(+/+) males much more than Cyp1a1(+/+) females, or in Cyp1a1(-/-) mice. Contrary to Cyp1a2(-/-) knockout mice that exhibited 15 times less accumulation of TCDD in liver than Cyp1a1/1a2(+/+) wild-type mice, Cyp1a1(-/-) mice did not show this altered TCDD distribution - indicating that CYP1A2 but not CYP1A1 is the major hepatic TCDD-binding 'sink'. Our data demonstrate that CYP1A1 contributes to high-dose TCDD-induced toxicity, uroporphyria, and lethality

  3. The determination of effective doses from the intake of tritiated water

    International Nuclear Information System (INIS)

    1987-08-01

    To comply with the regulatory requirements relating to the dose from exposures to tritiated water (HTO), Atomic Energy Control Board (AECB) licensees currently measure tritium concentration in urine to determine whole body dose. This approach has been based on the consideration that the time-integrated tritium concentration (which is proportional to accumulated dose) in any organ from urine concentrations are always conservative. The International Commission on Radiological Protection (ICRP) recommends that the average soft tissue dose be used to determine effective dose equivalents for HTO exposures. The ICRP also recommends that only the retention in body water be considered when committed doses from HTO exposures are calculated; this recommendation is based on the consideration that the errors introduced by neglecting the long-lived tritium component (those tritium atoms retained in organic molecules of the body cells) are small (only of the order of 10% of the committed dose equivalent to the whole body). The AECB position is presented in the following regulatory policy statement

  4. Radiation dose measurements of the insertion devices using radiachromic film dosimeters

    International Nuclear Information System (INIS)

    Alderman, J.; Semones, E.; Job, P. K.

    2004-01-01

    The Advanced Photon Source (APS) uses Nd-Fe-B permanent magnets in the insertion devices to produce x-rays for scientific research [1,2]. Earlier investigations have exhibited varying degrees of demagnetization of these magnets [3] due to irradiation from electron beams [4,5,6], 60 Co γ-rays [5], and high-energy neutrons [7,8]. Radiation-induced demagnetization has been observed in the APS insertion devices [9] and was first measured in December of 2001. Partial demagnetization has also been observed in insertion devices at the European Synchrotron Radiation Facility (ESRF) [4,6], where Nd-Fe-B permanent magnets are also used. Growing concern for the lifetime of APS insertion devices, as well as the permanent magnets that will be used in next-generation, high-power light sources, like the FEL [10,11], resulted from the partial demagnetization observations made at both facilities. This concern in relation to radiation-induced demagnetization spurred a long-term project to measure and analyze the absorbed doses received by the APS insertion devices. The project required a reliable photon high-dose dosimetry technique capable of measuring absorbed doses greater than 10 6 rad, which was not readily available at the APS. Through a collaboration with the National Institute of Standards and Technology (NIST), one such technique using radiachromic films was considered, tested, and calibrated at the APS. This consequently led to the implementation of radiachromic film dosimetry for measuring the absorbed doses received by the insertion devices for each of the APS runs

  5. Measurements of thorium-B (212Pb) in the outdoor environment and evaluation of equivalent dose

    International Nuclear Information System (INIS)

    Mohammed, A.; El-Hussein, A.; Ali, A.E.

    2000-01-01

    The activity size distribution of unattached as well as attached 212 Pb to aerosol particles was measured in the open air of El-Minia City, Egypt. The samples were collected using a wire screen diffusion battery technique and a low pressure cascade impactor. The mean activity median thermodynamic diameter (AMTD) of unattached 212 Pb was determined to be 1.4 nm with a relative mean geometric standard deviation (σ g ) of 1.55. A mean unattached fraction (f p ) of 0.03±0.007 was obtained at a mean aerosol particle concentration of 32x10 3 cm -3 . Sometimes the f p values were less than the detection limit of 0.008. The mean concentration of activity of 212 Pb was found to be 9.6±1.1 mBq m -3 . The mean activity median aerodynamic diameter (AMAD) of the accumulation mode of attached 212 Pb was determined to be 360 nm with a mean (σ g ) of 2.7. The mean value of specific air activity concentration of 212 Pb associated with that mode was determined to be 303±12 mBq m -3 . With a dosimetric model calculation (International Commission on Radiological Protection. Human respiratory tract model for radiological protection. Oxford: Pergamon Press, ICRP Publication 66, 1994) the total deposition fractions as well as total equivalent and effective dose have been evaluated considering the obtained parameters of the activity size distributions. At a total deposition fraction of about 97% for unattached activities the total equivalent and effective doses to the lung were determined to be about 0.18 and 0.02 μSv, respectively, while total equivalent and effective doses of about 0.45 and 0.05 μ Sv, respectively, were determined at a total deposition fraction of about 23% for the attached activities

  6. Entrance surface dose distribution and organ dose assessment for cone-beam computed tomography using measurements and Monte Carlo simulations with voxel phantoms

    Science.gov (United States)

    Baptista, M.; Di Maria, S.; Vieira, S.; Vaz, P.

    2017-11-01

    Cone-Beam Computed Tomography (CBCT) enables high-resolution volumetric scanning of the bone and soft tissue anatomy under investigation at the treatment accelerator. This technique is extensively used in Image Guided Radiation Therapy (IGRT) for pre-treatment verification of patient position and target volume localization. When employed daily and several times per patient, CBCT imaging may lead to high cumulative imaging doses to the healthy tissues surrounding the exposed organs. This work aims at (1) evaluating the dose distribution during a CBCT scan and (2) calculating the organ doses involved in this image guiding procedure for clinically available scanning protocols. Both Monte Carlo (MC) simulations and measurements were performed. To model and simulate the kV imaging system mounted on a linear accelerator (Edge™, Varian Medical Systems) the state-of-the-art MC radiation transport program MCNPX 2.7.0 was used. In order to validate the simulation results, measurements of the Computed Tomography Dose Index (CTDI) were performed, using standard PMMA head and body phantoms, with 150 mm length and a standard pencil ionizing chamber (IC) 100 mm long. Measurements for head and pelvis scanning protocols, usually adopted in clinical environment were acquired, using two acquisition modes (full-fan and half fan). To calculate the organ doses, the implemented MC model of the CBCT scanner together with a male voxel phantom ("Golem") was used. The good agreement between the MCNPX simulations and the CTDIw measurements (differences up to 17%) presented in this work reveals that the CBCT MC model was successfully validated, taking into account the several uncertainties. The adequacy of the computational model to map dose distributions during a CBCT scan is discussed in order to identify ways to reduce the total CBCT imaging dose. The organ dose assessment highlights the need to evaluate the therapeutic and the CBCT imaging doses, in a more balanced approach, and the

  7. Use of virtual reality to estimate radiation dose rates in nuclear plants

    International Nuclear Information System (INIS)

    Augusto, Silas C.; Mol, Antonio C.A.; Jorge, Carlos A.F.; Couto, Pedro M.

    2007-01-01

    Operators in nuclear plants receive radiation doses during several different operation procedures. A training program capable of simulating these operation scenarios will be useful in several ways, helping the planning of operational procedures so as to reduce the doses received by workers, and to minimize operations' times. It can provide safe virtual operation training, visualization of radiation dose rates, and estimation of doses received by workers. Thus, a virtual reality application, a free game engine, has been adapted to achieve the goals of this project. Simulation results for Argonauta research reactor of Instituto de Engenharia Nuclear are shown in this paper. A database of dose rate measurements, previously performed by the radiological protection service, has been used to display the dose rate distribution in the region of interest. The application enables the user to walk in the virtual scenario, displaying at all times the dose accumulated by the avatar. (author)

  8. Dose in the uterus of a woman, with three months of pregnancy, due to the {sup 131} I accumulated in her thyroid gland; Dosis en el utero de una mujer, con tres meses de embarazo, debida la {sup 131} I acumulado en su glandula tiroides

    Energy Technology Data Exchange (ETDEWEB)

    Vega C, H R; Manzanares A, E; Hernandez D, V M; Arcos P, A [Unidades Academicas de Estudios Nucleares e Ingenieria Electrica, Universidad Autonoma de Zacatecas, C. Cipres 10, Fracc. La Penuela, 98068 Zacatecas (Mexico)

    2006-07-01

    In this study the absorbed dose by the uterus of a woman with three months of pregnancy to who was applied a dose of {sup 131} I that was accumulated in the thyroid gland is determined. The absorbed dose was obtained by means of Monte Carlo calculations developing a detailed three-dimensional model of the pregnant one, where they have been included most of the organs. The absorbed dose also was calculated by means of a simple procedure. To verify the calculated results it was carried out an experiment where was constructed a phantom of the neck, in this was included the thyroid with {sup 131} I and the exposure was measured at different distances of the neck; this was related with the dose. Of the Monte Carlo calculation is obtained that for each mCi of {sup 131} I that is retained in the mother's thyroid, the uterus absorbs a dose of 6.80 E(-11) Gy. When comparing the results, it was found that the simple calculation throws a result 29 times superior to that of the dose obtained by means of Monte Carlo. When applying a correction for the effect of the absorption of the gamma photons by the mother's body an absorbed dose in the uterus was obtained that is 0.16 times superior to the Monte Carlo calculation. Of the experimental phase it is verified that the values calculated by means of the simple method are equal to those experimentally measured. (Author)

  9. Long distance elementary measurement of the radiation dose ratio produced by neutron activation

    International Nuclear Information System (INIS)

    Zhou Changgeng; Lou Benchao; Wu Chunlei; Hu Yonghong; Li Yan

    2009-04-01

    The working principle and the structure and performances of a long distance controllable individual radiation dose ratio instrument are described. The radiation dose ratio produced by neutron activation is elementarily measured by using this instrument in the neutron generator hall with high neutron yield. When neutron yield arrives to 2 x 10 11 s -1 , the radiation dose ratio produced by neutron activation is 99.9 μSv/h in 1 h after the generator being stopped. The radiation dose ratio is reduced to 24.4 μSv/h in 39 h after the generator being stopped. When neutron yield is 3.2 x 10 10 s -1 , the radiation dose ratio produced by neutron activation is 21.9 μSv/h in 36 min, after the generator being stopped. The measurement results may provide reference for physical experimenters and neutron generator operators. (authors)

  10. The application of computer and automatic technology in dose measurement of neutron radiation

    International Nuclear Information System (INIS)

    Zhou Yu; Li Chenglin; Luo Yisheng; Guo Yong; Chen Di; Xiaojiang

    1999-01-01

    Generally the dose measurement of neutron radiation requires three electrometers, two bias, three workers in the same time. To improve the accuracy and efficiency of measurement, a Model 6517A electrometer that accommodate Model 6521 scanner cards and a portable computer are used to make up of a automatic measurement system. Corresponding software is developed and used to control it. Because of the application of computer and automatic technology, this system can not only measure dose rate automatically, but also make data's calculating, saving, querying, printing and comparing ease

  11. Experimental evaluation of a MOSFET dosimeter for proton dose measurements

    International Nuclear Information System (INIS)

    Kohno, Ryosuke; Nishio, Teiji; Miyagishi, Tomoko; Hirano, Eriko; Hotta, Kenji; Kawashima, Mitsuhiko; Ogino, Takashi

    2006-01-01

    The metal oxide semiconductor field-effect transistor (MOSFET) dosimeter has been widely studied for use as a dosimeter for patient dose verification. The major advantage of this detector is its size, which acts as a point dosimeter, and also its ease of use. The commercially available TN502RD MOSFET dosimeter manufactured by Thomson and Nielsen has never been used for proton dosimetry. Therefore we used the MOSFET dosimeter for the first time in proton dose measurements. In this study, the MOSFET dosimeter was irradiated with 190 MeV therapeutic proton beams. We experimentally evaluated dose reproducibility, linearity, fading effect, beam intensity dependence and angular dependence for the proton beam. Furthermore, the Bragg curve and spread-out Bragg peak were also measured and the linear-energy transfer (LET) dependence of the MOSFET response was investigated. Many characteristics of the MOSFET response for proton beams were the same as those for photon beams reported in previous papers. However, the angular MOSFET responses at 45, 90, 135, 225, 270 and 315 degrees for proton beams were over-responses of about 15%, and moreover the MOSFET response depended strongly on the LET of the proton beam. This study showed that the angular dependence and LET dependence of the MOSFET response must be considered very carefully for quantitative proton dose evaluations

  12. Measurement of the primary and scatter dose in high energy photon beams

    Energy Technology Data Exchange (ETDEWEB)

    Van der Linden, P M [Catharina Ziekenhuis, Eindhoven (Netherlands). Radiotherapy Dept.; Tiourina, T B; Dries, W

    1995-12-01

    A method is presented to measure the primary and scatter components separately in a water tank using a small cylindrical absorber. Results from this experiment are compared with Monte Carlo calculations. The measurement setup consists of a small cylindrical absorber placed on a central axis of the beam a few centimetres above the radiation detector. Both absorber and detector move along the central axis while absorbed dose is registered. As the primary radiation is fully blocked, only scatter component is measured when a cylindrical absorber is used. Measurements in open fields result in the total absorbed dose being the sum of primary and scatter components. The primary dose component can be derived by substraction. Absorbers with different diameters are used. With decreasing dimensions the relative contribution of the dose due to scatter radiation increases. A steep increase is observed when the range of laterally scattered electrons becomes comparable with the radius of the absorber. Two different Monte Carlo simulations have been performed: with and without secondary electron transport. The data obtained for the former case perfectly agrees with the experiment. The situation where the secondary electron is assumed zero (i.e. local energy deposition) simulates the Cunningham model. Our results show that the Cunningham model predicts lower scatter component under the block edge which can be important for these applications.

  13. A scintillating gas detector for 2D dose measurements in clinical carbon beams.

    Science.gov (United States)

    Seravalli, E; de Boer, M; Geurink, F; Huizenga, J; Kreuger, R; Schippers, J M; van Eijk, C W E; Voss, B

    2008-09-07

    A two-dimensional position sensitive dosimetry system based on a scintillating gas detector has been developed for pre-treatment verification of dose distributions in hadron therapy. The dosimetry system consists of a chamber filled with an Ar/CF4 scintillating gas mixture, inside which two cascaded gas electron multipliers (GEMs) are mounted. A GEM is a thin kapton foil with copper cladding structured with a regular pattern of sub-mm holes. The primary electrons, created in the detector's sensitive volume by the incoming beam, drift in an electric field towards the GEMs and undergo gas multiplication in the GEM holes. During this process, photons are emitted by the excited Ar/CF4 gas molecules and detected by a mirror-lens-CCD camera system. Since the amount of emitted light is proportional to the dose deposited in the sensitive volume of the detector by the incoming beam, the intensity distribution of the measured light spot is proportional to the 2D hadron dose distribution. For a measurement of a 3D dose distribution, the scintillating gas detector is mounted at the beam exit side of a water-bellows phantom, whose thickness can be varied in steps. In this work, the energy dependence of the output signal of the scintillating gas detector has been verified in a 250 MeV/u clinical 12C ion beam by means of a depth-dose curve measurement. The underestimation of the measured signal at the Bragg peak depth is only 9% with respect to an air-filled ionization chamber. This is much smaller than the underestimation found for a scintillating Gd2O2S:Tb ('Lanex') screen under the same measurement conditions (43%). Consequently, the scintillating gas detector is a promising device for verifying dose distributions in high LET beams, for example to check hadron therapy treatment plans which comprise beams with different energies.

  14. Direct measurement of dose at depth in breast cancer using lithium fluoride

    Energy Technology Data Exchange (ETDEWEB)

    Dawes, P J.D.K.; Aird, E G; Crawshaw, I P

    1988-05-01

    In 23 cases of breast cancer treated conservatively using external beam and interstitial radiotherapy, lithium fluoride thermoluminescent dosimetry has been used to measure the radiation dose received by the breast tissue at depth. Thirty-six investigations were made using a number of lithium fluoride micro-rods for each investigation. Three results could not be analysed because of measurement problems in two and insufficient information in one. Twenty-eight results were obtained at a depth in tissue greater than the build-up zone, 23 of the 28 falling within +- 5% and 27 of the 28 falling within +- 10% of the computer-calculated prescribed dose. Of five results obtained within the build-up zone, two fell within +- 5% and four within +- 10% of the prescribed dose.

  15. Outline of manual on measurement and assessment of doses from external radiation

    Energy Technology Data Exchange (ETDEWEB)

    Yoshizawa, Michio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Tsujimura, Norio

    2001-03-01

    The external exposure part in the manual for measurement and assessment of doses from external radiation is described since the part is changed in accordance with the revision of the Law Concerning Prevention from Radiation Hazard due to Radioisotopes, Etc. The manual contains general remarks, control of external exposure and its methods, person monitoring, site monitoring, correction of instruments and storage of records. The 2nd and 3rd chapters are described in details, because which are considerably changed together with appendices concerning the operational quantity for measuring external dose, conversion coefficients, and correlations of 3 mm, 1 cm and 70 {mu}m dose equivalents. Making manuals unique to the individual offices, etc. is recommended in compliance with the above manual.(K.H.)

  16. Alanine and TLD coupled detectors for fast neutron dose measurements in neutron capture therapy (NCT)

    Energy Technology Data Exchange (ETDEWEB)

    Cecilia, A.; Baccaro, S.; Cemmi, A. [ENEA-FIS-ION, Casaccia RC, Via Anguillarese 301, 00060 Santa Maria di Galeria, Rome (Italy); Colli, V.; Gambarini, G. [Dept. of Physics of the Univ., INFN, Via Celoria 16, 20133 Milan (Italy); Rosi, G. [ENEA-FIS-ION, Casaccia RC, Via Anguillarese 301, 00060 Santa Maria di Galeria, Rome (Italy); Scolari, L. [Dept. of Physics of the Univ., INFN, Via Celoria 16, 20133 Milan (Italy)

    2004-07-01

    A method was investigated to measure gamma and fast neutron doses in phantoms exposed to an epithermal neutron beam designed for neutron capture therapy (NCT). The gamma dose component was measured by TLD-300 [CaF{sub 2}:Tm] and the fast neutron dose, mainly due to elastic scattering with hydrogen nuclei, was measured by alanine dosemeters [CH{sub 3}CH(NH{sub 2})COOH]. The gamma and fast neutron doses deposited in alanine dosemeters are very near to those released in tissue, because of the alanine tissue equivalence. Couples of TLD-300 and alanine dosemeters were irradiated in phantoms positioned in the epithermal column of the Tapiro reactor (ENEA-Casaccia RC). The dosemeter response depends on the linear energy transfer (LET) of radiation, hence the precision and reliability of the fast neutron dose values obtained with the proposed method have been investigated. Results showed that the combination of alanine and TLD detectors is a promising method to separate gamma dose and fast neutron dose in NCT. (authors)

  17. Cytogenetic investigations of persons exposed to professional chronic low-dose irradiation

    International Nuclear Information System (INIS)

    Rangelov, V.; Mitev, L.; Petrunov, P.; Vesselinova, L.

    2005-01-01

    The problem of long term influence of low-doses occupational irradiation is connected with the real assessment of their consequences. The current cytogenetic investigations were done on persons working under occupational chronic external partial irradiation. Accumulated doses of external irradiation are surveyed. Data give ground for suggestion about the relationship between accumulated dose and chromosomal aberrations. The additional damage factors (diagnostic investigations, chemical substances, tobacco addict) have done the more significant influence upon aberrations appearance increasing

  18. Assessment of ambient gamma dose rate around a prospective uranium mining area of South India - A comparative study of dose by direct methods and soil radioactivity measurements

    Science.gov (United States)

    Karunakara, N.; Yashodhara, I.; Sudeep Kumara, K.; Tripathi, R. M.; Menon, S. N.; Kadam, S.; Chougaonkar, M. P.

    Indoor and outdoor gamma dose rates were evaluated around a prospective uranium mining region - Gogi, South India through (i) direct measurements using a GM based gamma dose survey meter, (ii) integrated measurement days using CaSO4:Dy based thermo luminescent dosimeters (TLDs), and (iii) analyses of 273 soil samples for 226Ra, 232Th, and 40K activity concentration using HPGe gamma spectrometry. The geometric mean values of indoor and outdoor gamma dose rates were 104 nGy h-1 and 97 nGy h-1, respectively with an indoor to outdoor dose ratio of 1.09. The gamma dose rates and activity concentrations of 226Ra, 232Th, and 40K varied significantly within a small area due to the highly localized mineralization of the elements. Correlation study showed that the dose estimated from the soil radioactivity is better correlated with that measured directly using the portable survey meter, when compared to that obtained from TLDs. This study showed that in a region having localized mineralization in situ measurements using dose survey meter provide better representative values of gamma dose rates.

  19. Genomic instability in mutation induction on normal human fibroblasts irradiated with chronic low-dose radiations in heavy-ion radiation field

    International Nuclear Information System (INIS)

    Suzuki, M.; Tsuruoka, C.; Uchihori, Y.; Yasuda, H.; Fujitaka, K.

    2003-01-01

    Full text: At a time when manned space exploration is more a reality with the planned the International Space Station (ISS) underway, the potential exposure of crews in a spacecraft to chronic low-dose radiations in the field of low-flux galactic cosmic rays (GCR) and the subsequent biological effects have become one of the major concerns of space science. We have studied both in vitro life span and genomic instability in cellular effects in normal human skin fibroblasts irradiated with chronic low-dose radiations in heavy-ion radiation field. Cells were cultured in a CO2 incubator, which was set in the irradiation room for the biological study of heavy ions in the Heavy Ion Medical Accelerator in Chiba (HIMAC) at National Institute of Radiological Sciences (NIRS), and irradiated with scattered radiations produced from heavy ions. Absorbed dose measured using a thermoluminescence dosimeter (TLD) and a Si-semiconductor detector was to be around 1.4 mGy per day when operating the HIMAC machine for biological experiments. The total population doubling number (tPDN) of low-dose irradiated cells was significantly smaller (79-93%) than that of unirradiated cells. The results indicate that the life span of the cell population shortens by irradiating with low-dose scattered radiations in the heavy-ion irradiation field. Genomic instability in cellular responses was examined to measure either cell killing or mutation induction in low-dose accumulated cells after exposing to X-ray challenging doses. The results showed that there was no enhanced effect on cell killing between low-dose accumulated and unirradiated cells after exposing to defined challenging doses of 200kV X rays. On the contrary, the mutation frequency on hprt locus of low-dose accumulated cells was much higher than that of unirradiated cells. The results suggested that genomic instability was induced in mutagenesis by the chronic low-dose irradiations in heavy-ion radiation field

  20. Using an electronic portal imaging device for exit dose measurements in radiotherapy

    International Nuclear Information System (INIS)

    Ganowicz, M.; Wozniak, B.; Bekman, A.; Maniakowski, Z.

    2003-01-01

    To present a method of determining the exit dose with the use of an electronic portal imaging device (EPID). The device used was the Portal Vision LC250 (Varian). The EPID signals on the central beam axis have been related to the exit dose. The exit dose measurements were performed with the ionisation chamber in the slab phantom at the distance of dose maximum from the exit surface of the phantom. EPID reading was investigated as a function of field size, phantom thickness and source-detector distance. The relation between dose rate and the EPID reading is described with empirical functions applicable to the obtained data. The exit dose is calculated from the EPID reading as a product of the calibration factor and appropriate correction factors. The determination of the exit dose rate from the EPID signal requires the knowledge of many parameters and earlier determination of essential characteristics. (author)

  1. Serial measurement of radiation leakage dose rates in safekeeping at the Gammaknife room

    International Nuclear Information System (INIS)

    Baba, Sadaaki; Nozaki, Kenichi; Toyoda, Tatsuya; Wakamatsu, Osamu; Machida, Toru

    2006-01-01

    We report the serial measurement of leakage dose rates in safekeeping at the Gammaknife room during the past 4 years and 9 months by scintillation survey meter. The leakage dose rates at the radiation boundaries were the same as the natural background levels. Leakage dose rates at each shield calculation point from two 90 Sr calibration sources contained in the storehouse were negligible compared with those from 60 Co sources of the Gammaknife. 60 Co sources of the Gammaknife are arranged in 201 pieces at 10 degree interval on the circumference and in five lines within an arc of 35 degrees. Its shield container is made of iron at least 43 cm thick. We got leakage dose rates less than 40% of the calculated values. We think it is caused by the difference of each actual distance and shield thickness because 60 Co sources are usually considered as a point source in the shield calculation. There are shutters opening up and down when patients go in and out to the direction of the couch. The leakage values to this direction were about twice as much as the calculated value. So, we knew the thickness of those shutters was thinner than 43 cm. The half life time of 60 Co source calculated from the serial measurements of leakage dose rates was 4.93 years on average. It is 94% of the physical half life value of 5.27 years. We judged it was acceptable considering the difficulty of measuring low dose rate level with the radiation survey meter. Very strong correlation was observed between the decrease of 60 Co dose rate acquired from one minute measurement at the center of 18 cm diameter polysterene phantom gotten from December 2000 to August 2005 and that of computation based on the physical half life time. Likewise there was strong and more correlation with leakage dose rate in the Gammaknife room. From this, we deduce the leakage dose rate decreases according to the theory of the disintegration of radioactivity with passage of time. Revised radiation related laws took effect

  2. The measurement of dose at 70 micrometres' depth using thermoluminescent dosimeters (tlds)

    International Nuclear Information System (INIS)

    Jones, A.R.

    1989-01-01

    The measurement of dose with thermoluminescent dosimeters (TLD) at a tissue-equivalent depth of 70 μm can be done in three ways. These are by using: very thin TLDs (made by cementing fine, powdered, TLD particles to a high-temperature plastic film); opaque TLDs whose surface alone is sensitive. (Light emitted at a greater depth has a low probability of emergence and, thus, they behave as if they were thin.); at least three TLDs covered with absorbers of differing thickness. The approaches were studied using examples of dosimeter arrangements of the three types. The characteristics which were measured to form a basis of comparison were: the performance at high and low doses; the effect of changing angle of incidence and beta-ray energy; the effect on performance of repeated irradiation, annealing and reading. It was concluded that the very thin TLDs (powdered) are the best suited to the measurement of doses at 70 μm depth

  3. Comparison of 3-dimensional dose reconstruction system between fluence-based system and dose measurement-guided system

    Energy Technology Data Exchange (ETDEWEB)

    Nakaguchi, Yuji, E-mail: nkgc2003@yahoo.co.jp [Department of Radiological Technology, Kumamoto University Hospital, Kumamoto (Japan); Ono, Takeshi [Faculty of Life Sciences, Kumamoto University, Kumamoto (Japan); Onitsuka, Ryota [Graduate School of Health Sciences, Kumamoto University, Kumamoto (Japan); Maruyama, Masato; Shimohigashi, Yoshinobu; Kai, Yudai [Department of Radiological Technology, Kumamoto University Hospital, Kumamoto (Japan)

    2016-10-01

    COMPASS system (IBA Dosimetry, Schwarzenbruck, Germany) and ArcCHECK with 3DVH software (Sun Nuclear Corp., Melbourne, FL) are commercial quasi-3-dimensional (3D) dosimetry arrays. Cross-validation to compare them under the same conditions, such as a treatment plan, allows for clear evaluation of such measurement devices. In this study, we evaluated the accuracy of reconstructed dose distributions from the COMPASS system and ArcCHECK with 3DVH software using Monte Carlo simulation (MC) for multi-leaf collimator (MLC) test patterns and clinical VMAT plans. In a phantom study, ArcCHECK 3DVH showed clear differences from COMPASS, measurement and MC due to the detector resolution and the dose reconstruction method. Especially, ArcCHECK 3DVH showed 7% difference from MC for the heterogeneous phantom. ArcCHECK 3DVH only corrects the 3D dose distribution of treatment planning system (TPS) using ArcCHECK measurement, and therefore the accuracy of ArcCHECK 3DVH depends on TPS. In contrast, COMPASS showed good agreement with MC for all cases. However, the COMPASS system requires many complicated installation procedures such as beam modeling, and appropriate commissioning is needed. In terms of clinical cases, there were no large differences for each QA device. The accuracy of the compass and ArcCHECK 3DVH systems for phantoms and clinical cases was compared. Both systems have advantages and disadvantages for clinical use, and consideration of the operating environment is important. The QA system selection is depending on the purpose and workflow in each hospital.

  4. SU-F-P-56: On a New Approach to Reconstruct the Patient Dose From Phantom Measurements

    International Nuclear Information System (INIS)

    Bangtsson, E; Vries, W de

    2016-01-01

    Purpose: The development of complex radiation treatment schemes emphasizes the need for advanced QA analysis methods to ensure patient safety. One such tool is the Delta4 DVH Anatomy software, where the patient dose is reconstructed from phantom measurements. Deviations in the measured dose are transferred to the patient anatomy and their clinical impact is evaluated in situ. Results from the original algorithm revealed weaknesses that may introduce artefacts in the reconstructed dose. These can lead to false negatives or obscure the effects of minor dose deviations from delivery failures. Here, we will present results from a new patient dose reconstruction algorithm. Methods: The main steps of the new algorithm are: (1) the dose delivered to a phantom is measured in a number of detector positions. (2) The measured dose is compared to an internally calculated dose distribution evaluated in said positions. The so-obtained dose difference is (3) used to calculate an energy fluence difference. This entity is (4) used as input to a patient dose correction calculation routine. Finally, the patient dose is reconstructed by adding said patient dose correction to the planned patient dose. The internal dose calculation in step (2) and (4) is based on the Pencil Beam algorithm. Results: The new patient dose reconstruction algorithm have been tested on a number of patients and the standard metrics dose deviation (DDev), distance-to-agreement (DTA) and Gamma index are improved when compared to the original algorithm. In a certain case the Gamma index (3%/3mm) increases from 72.9% to 96.6%. Conclusion: The patient dose reconstruction algorithm is improved. This leads to a reduction in non-physical artefacts in the reconstructed patient dose. As a consequence, the possibility to detect deviations in the dose that is delivered to the patient is improved. An increase in Gamma index for the PTV can be seen. The corresponding author is an employee of ScandiDos

  5. SU-F-P-56: On a New Approach to Reconstruct the Patient Dose From Phantom Measurements

    Energy Technology Data Exchange (ETDEWEB)

    Bangtsson, E [ScandiDos, Uppsala (Sweden); Vries, W de [University Medical Center Utrecht, Utrecht (Netherlands)

    2016-06-15

    Purpose: The development of complex radiation treatment schemes emphasizes the need for advanced QA analysis methods to ensure patient safety. One such tool is the Delta4 DVH Anatomy software, where the patient dose is reconstructed from phantom measurements. Deviations in the measured dose are transferred to the patient anatomy and their clinical impact is evaluated in situ. Results from the original algorithm revealed weaknesses that may introduce artefacts in the reconstructed dose. These can lead to false negatives or obscure the effects of minor dose deviations from delivery failures. Here, we will present results from a new patient dose reconstruction algorithm. Methods: The main steps of the new algorithm are: (1) the dose delivered to a phantom is measured in a number of detector positions. (2) The measured dose is compared to an internally calculated dose distribution evaluated in said positions. The so-obtained dose difference is (3) used to calculate an energy fluence difference. This entity is (4) used as input to a patient dose correction calculation routine. Finally, the patient dose is reconstructed by adding said patient dose correction to the planned patient dose. The internal dose calculation in step (2) and (4) is based on the Pencil Beam algorithm. Results: The new patient dose reconstruction algorithm have been tested on a number of patients and the standard metrics dose deviation (DDev), distance-to-agreement (DTA) and Gamma index are improved when compared to the original algorithm. In a certain case the Gamma index (3%/3mm) increases from 72.9% to 96.6%. Conclusion: The patient dose reconstruction algorithm is improved. This leads to a reduction in non-physical artefacts in the reconstructed patient dose. As a consequence, the possibility to detect deviations in the dose that is delivered to the patient is improved. An increase in Gamma index for the PTV can be seen. The corresponding author is an employee of ScandiDos.

  6. Alanine-EPR dosimetry system for high industrial as well radiotherapeutic dose measurement

    International Nuclear Information System (INIS)

    Dobrovodsky, J.; Bukovjan, J.

    2005-01-01

    Slovak Institute of Metrology is developing new metrology standard for high doses, based on the alanine-EPR as a reference dosimetry system. A Bruker e-scan EPR analyser developed specifically for alanine dosimetry has improved stability of EPR measurement, especially at lower dose range. The standard e-scan system provides sensitivity below 1 Gray. After further improvement of the system and lowering of dose determination expanded uncertainty down below 1 %, its utilisation for radiotherapy field is expected (authors)

  7. Radiation Dose Assesment And Risk Estimation During Extracorporeal Shock Wave Lithotripsy

    International Nuclear Information System (INIS)

    Sulieman, A.; Ibrahim, A.A.; Osman, H.; Yousef, M.

    2011-01-01

    Extracorporeal shockwave lithotripsy (ESWL) is considered the gold standard for calculi fragmentation. The aims of this study are to measure the entrance surface dose (ESD) using thermo-luminescence dosimeter (TLDs) and to estimate the probability of carcinogenesis during ESWL procedure. The study was carried out at two centers (Group A, 50 patients) and (Group B, 25 patients). The mean ESD and effective doses were 36 mGy and 34 mSv. The results show that the probability of carcinogenesis is a tiny value 100 per million patients) but the main biological effect is occurring due to the accumulative impact of radiation.

  8. Whole-body dose meters. Measurements of total activity

    International Nuclear Information System (INIS)

    Koeppe, P.; Klinikum Steglitz, Berlin

    1990-01-01

    By means of measurements using a whole-body dose meter, the course of the incorporation of radionuclides was established between April 1986 and May 1989 for unchanged conditions of alimentation, activity-conscious alimentation, and uniquely increased incorporation. Monitoring covered persons from the most different spheres of life. The incorporation is compared with the one resulting from nuclear weapons explosions in the atmosphere. (DG) [de

  9. Outdoor solar UVA dose assessment with EBT2 radiochromic film using spectrophotometer and densitometer measurements

    International Nuclear Information System (INIS)

    Abukassem, I.; Bero, M.A.

    2015-01-01

    Direct measurements of solar ultraviolet radiations (UVRs) have an important role in the protection of humans against UVR hazard. This work presents simple technique based on the application of EBT2 GAFCHROMIC R film for direct solar UVA dose assessment. It demonstrates the effects of different parts of the solar spectrum (UVB, visible and infrared) on performed UVA field measurements and presents the measurement uncertainty budget. The gradient of sunlight exposure level permitted the authors to establish the mathematical relationships between the measured solar UVA dose and two measured quantities: the first was the changes in spectral absorbance at the wavelength 633 nm (A 633 ) and the second was the optical density (OD). The established standard relations were also applied to calculate the solar UVA dose variations during the whole day; 15 min of exposure each hour between 8:00 and 17:00 was recorded. Results show that both applied experimental methods, spectrophotometer absorbance and densitometer OD, deliver comparable figures for EBT2 solar UVA dose assessment with relative uncertainty of 11 % for spectral absorbance measurements and 15 % for OD measurements. (authors)

  10. Benchmark measurements and simulations of dose perturbations due to metallic spheres in proton beams

    International Nuclear Information System (INIS)

    Newhauser, Wayne D.; Rechner, Laura; Mirkovic, Dragan; Yepes, Pablo; Koch, Nicholas C.; Titt, Uwe; Fontenot, Jonas D.; Zhang, Rui

    2013-01-01

    Monte Carlo simulations are increasingly used for dose calculations in proton therapy due to its inherent accuracy. However, dosimetric deviations have been found using Monte Carlo code when high density materials are present in the proton beamline. The purpose of this work was to quantify the magnitude of dose perturbation caused by metal objects. We did this by comparing measurements and Monte Carlo predictions of dose perturbations caused by the presence of small metal spheres in several clinical proton therapy beams as functions of proton beam range and drift space. Monte Carlo codes MCNPX, GEANT4 and Fast Dose Calculator (FDC) were used. Generally good agreement was found between measurements and Monte Carlo predictions, with the average difference within 5% and maximum difference within 17%. The modification of multiple Coulomb scattering model in MCNPX code yielded improvement in accuracy and provided the best overall agreement with measurements. Our results confirmed that Monte Carlo codes are well suited for predicting multiple Coulomb scattering in proton therapy beams when short drift spaces are involved. - Highlights: • We compared measurements and Monte Carlo predictions of dose perturbations caused by the metal objects in proton beams. • Different Monte Carlo codes were used, including MCNPX, GEANT4 and Fast Dose Calculator. • Good agreement was found between measurements and Monte Carlo simulations. • The modification of multiple Coulomb scattering model in MCNPX code yielded improved accuracy. • Our results confirmed that Monte Carlo codes are well suited for predicting multiple Coulomb scattering in proton therapy

  11. VMAT QA: Measurement-guided 4D dose reconstruction on a patient

    Energy Technology Data Exchange (ETDEWEB)

    Nelms, Benjamin E.; Opp, Daniel; Robinson, Joshua; Wolf, Theresa K.; Zhang, Geoffrey; Moros, Eduardo; Feygelman, Vladimir [Canis Lupus LLC, Merrimac, Wisconsin 53561 (United States); Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida 33612 (United States); Department of Physics, University of South Florida, Tampa, Florida 33612 (United States); Live Oak Technologies LLC, Kirkwood, Missouri 63122 (United States); Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida 33612 (United States)

    2012-07-15

    Purpose: To develop and validate a volume-modulated arc therapy (VMAT) quality assurance (QA) tool that takes as input a time-resolved, low-density ({approx}10 mm) cylindrical surface dose map from a commercial helical diode array, and outputs a high density, volumetric, time-resolved dose matrix on an arbitrary patient dataset. This first validation study is limited to a homogeneous 'patient.'Methods: A VMAT treatment is delivered to a diode array phantom (ARCCHECK, Sun Nuclear Corp., Melbourne, FL). 3DVH software (Sun Nuclear) derives the high-density volumetric dose using measurement-guided dose reconstruction (MGDR). MGDR cylindrical phantom results are then used to perturb the three-dimensional (3D) treatment planning dose on the patient dataset, producing a semiempirical volumetric dose grid. Four-dimensional (4D) dose reconstruction on the patient is also possible by morphing individual sub-beam doses instead of the composite. For conventional (3D) dose comparison two methods were developed, using the four plans (Multi-Target, C-shape, Mock Prostate, and Head and Neck), including their structures and objectives, from the AAPM TG-119 report. First, 3DVH and treatment planning system (TPS) cumulative point doses were compared to ion chamber in a cube water-equivalent phantom ('patient'). The shape of the phantom is different from the ARCCHECK and furthermore the targets were placed asymmetrically. Second, coronal and sagittal absolute film dose distributions in the cube were compared with 3DVH and TPS. For time-resolved (4D) comparisons, three tests were performed. First, volumetric dose differences were calculated between the 3D MGDR and cumulative time-resolved patient (4D MGDR) dose at the end of delivery, where they ideally should be identical. Second, time-resolved (10 Hz sampling rate) ion chamber doses were compared to cumulative point dose vs time curves from 4D MGDR. Finally, accelerator output was varied to assess the linearity of

  12. Dose concentration and dose verification for radiotherapy of cancer

    International Nuclear Information System (INIS)

    Maruyama, Koichi

    2005-01-01

    The number of cancer treatments using radiation therapy is increasing. The background of this increase is the accumulated fact that the number of successful cases is comparative to or even better than surgery for some types of cancer due to the improvement in irradiation technology and radiation planning technology. This review describes the principles and technology of radiation therapy, its characteristics, particle therapy that improves the dose concentration, its historical background, the importance of dose concentration, present situation and future possibilities. There are serious problems that hinder the superior dose concentration of particle therapy. Recent programs and our efforts to solve these problems are described. A new concept is required to satisfy the notion of evidence based medicine, i.e., one has to develop a method of dose verification, which is not yet available. This review is for researchers, medical doctors and radiation technologists who are developing this field. (author)

  13. Estimation of computed tomography dose index in cone beam computed tomography: MOSFET measurements and Monte Carlo simulations.

    Science.gov (United States)

    Kim, Sangroh; Yoshizumi, Terry; Toncheva, Greta; Yoo, Sua; Yin, Fang-Fang; Frush, Donald

    2010-05-01

    To address the lack of accurate dose estimation method in cone beam computed tomography (CBCT), we performed point dose metal oxide semiconductor field-effect transistor (MOSFET) measurements and Monte Carlo (MC) simulations. A Varian On-Board Imager (OBI) was employed to measure point doses in the polymethyl methacrylate (PMMA) CT phantoms with MOSFETs for standard and low dose modes. A MC model of the OBI x-ray tube was developed using BEAMnrc/EGSnrc MC system and validated by the half value layer, x-ray spectrum and lateral and depth dose profiles. We compared the weighted computed tomography dose index (CTDIw) between MOSFET measurements and MC simulations. The CTDIw was found to be 8.39 cGy for the head scan and 4.58 cGy for the body scan from the MOSFET measurements in standard dose mode, and 1.89 cGy for the head and 1.11 cGy for the body in low dose mode, respectively. The CTDIw from MC compared well to the MOSFET measurements within 5% differences. In conclusion, a MC model for Varian CBCT has been established and this approach may be easily extended from the CBCT geometry to multi-detector CT geometry.

  14. Three dimensional measurements of absorbed dose in BNCT by Fricke-gel imaging

    International Nuclear Information System (INIS)

    Gambarini, G.; Agosteo, S.; Marchesi, P.; Nava, E.; Palazzi, P.; Pecci, A.; Rosa, R.; Rosi, G.; Tinti, R.

    2001-01-01

    A method has been studied for absorbed dose imaging and profiling in a phantom exposed to thermal or epithermal neutron fields, also discriminating between various contributions to the absorbed dose. The proposed technique is based on optical imaging of FriXy-gel phantoms, which are proper tissue-equivalent phantoms acting as continuous dosimeters. Convenient modifications in phantom composition allow, from differential measurements, the discrimination of various contributions to the absorbed dose. The dosimetry technique is based on a chemical dosimeter incorporated in a tissue-equivalent gel (Agarose). The chemical dosimeter is a ferrous sulphate solution (which is the main component of the standard Fricke dosimeter) added with a metal ion indicator (Xylenol Orange). The absorbed dose is measured by analysing the variation of gel optical absorption in the visible spectrum, imaged by means of a CCD camera provided with a suitable filter. The technique validity has been tested by irradiating and analysing phantoms in the thermal facility of the fast research reactor TAPIRO (ENEA, Casaccia, Italy). In a cylindrical phantom simulating a head, we have imaged the therapy dose from thermal neutron reactions with 10 B and the dose in healthy tissue not containing boron. In tissue without boron, we have discriminated between the two main contributions to the absorbed dose, which comes from the 1 H(n,γ) 2 H and 14 N(n,p) 14 C reactions. The comparison with the results of other experimental techniques and of simulations reveals that the technique is very promising. A method for the discrimination of fast neutron contribution to the absorbed dose, still in an experimental stage, is proposed too. (author)

  15. Direct measurement of dose at depth in breast cancer using lithium fluoride

    International Nuclear Information System (INIS)

    Dawes, P.J.D.K.; Aird, E.G.; Crawshaw, I.P.

    1988-01-01

    In 23 cases of breast cancer treated conservatively using external beam and interstitial radiotherapy, lithium fluoride thermoluminescent dosimetry has been used to measure the radiation dose received by the breast tissue at depth. Thirty-six investigations were made using a number of lithium fluoride micro-rods for each investigation. Three results could not be analysed because of measurement problems in two and insufficient information in one. Twenty-eight results were obtained at a depth in tissue greater than the build-up zone, 23 of the 28 falling within ± 5% and 27 of the 28 falling within ± 10% of the computer-calculated prescribed dose. Of five results obtained within the build-up zone, two fell within ± 5% and four within ± 10% of the prescribed dose. (author)

  16. Use of cadmium sulphide to measure integrated dose in short-time irradiation

    International Nuclear Information System (INIS)

    Nimnual, S.

    1975-01-01

    An experiment was made to measure the dose from a short burst of X-rays in the order of 1 second or less by means of the cadmium sulphide photoconductive cell. If protected from light, the CdS cell has a very high resistance such that it does not discharge a capacitor appreciably. But during irradiation, the resistance decreases temporarily and an amount of charge will leak from the capacitor through the Ca S cell. The result to this experiment shows that the principle works very well but it is necessary to add another fixed high resistance of about 10 7 ohms into the circuit in order to get results independent of the dose-rate. The equipment used in this experiment can measure a dose as low as 6 m R

  17. Study of the contribution of X-ray and gamma photons to the measured exposure dose

    International Nuclear Information System (INIS)

    Andriampanarivo, H.L.H.

    2000-01-01

    The aim of this work was to study the contribution of X-rays and gamma radiation to the measured dose in the city of Antananarivo. The annual indoor absorbed dose was studied as well. Measurements were carried out in twelve sites, namely public schools and churches. The mean dose rate lies between (0.34±0.03)μSv/h and (0.38±0.04)μSv/h for most of the sites. Two of them showed values between (0.40±0.04)μSv/h and (0.30±0.03)μSv/h. Mean indoor dose rate is of (0.36±0.04)μSv/h and the annual absorbed dose is (3.16±0.32)mSv/person. Indoor measurements showed mean integral values ranging from (277.22±0,22)cps to (733.66±0,37)cps. The lowest mean count rate is (277.22±0,22)cps, measured in the AMARO site, whereas the highest are (733,66±0,37)cps, (697,81±0,36)cps and (689,32±0,36)cps measured in ALO0 , AKELY, and MASINA respectively. [fr

  18. Efficacy of reduced doses of bentazone assessed by instruments based on measurement of chlorophyll fluorescence

    Directory of Open Access Journals (Sweden)

    Vojtěch Kocurek

    2011-01-01

    Full Text Available Chlorophyll fluorescence is a type of radiation emitted by plants as unused part of energy absorbed from sunlight. Its intensity depends on many stress factors, nutrition, weather conditions etc. Methods based on chlorophyll fluorescence measurement have potential to be perspective for the assessment of herbicide efficacy, phytotoxicity or stress influence. Two fluorometers (FluorCam and handy FluorPen were used for measurements in laboratory experiments in 2007–2009. Herbicide Basagran super with active ingredient bentazone (480 g.l−1 was tested using a parameter called ‚Quantum yield of fluorescence‘ (QY in three different doses: the registered dose 2.0 l.ha−1 (100% and lower doses 1.5 l.ha−1 (75% and 1.0 l.ha−1 (50%. Treated experimental plants of redroot pigweed (Amaranthus retroflexus L. were measured in 0, 1, 2, 3, 6, 9 and 15 days after treatment and the results were compared with subjective assessment (estimation and growth parameters. The obtained results showed that the effect of bentazone measured by both devices was statistically significantly different from untreated control. We can also detect herbicide effect earlier by QY measurement than by other methods. Different doses showed significant differences 15 days after treatment for dose 2.0 l.ha−1 in comparison with both reduced doses. The subjective assessment showed significant differences in all terms of measurement (1–15 days after application except of the day of application. Regeneration of plants for which the youngest leaves were not treated by herbicide was observed for all doses. Difference of QY values between used devices was on average 0.119 (higher for FluorCam but statistically insignificant.

  19. Development of an ICCD-scintillator system for measurement of spatial dose distributions around 'hot particles'

    International Nuclear Information System (INIS)

    Aydarous, A. Sh; Darley, P. J.; Charles, M. W.

    2004-01-01

    An intensified charge coupled device (ICCD)-scintillator system has been investigated for potential use in measuring the spatially non-uniform dose distribution around 'hot particles'. This imaging system is capable of producing real-time measurements considerably quicker than other presently available radiation dosimetry techniques and exhibits good linearity and reproducibility and relatively high spatial resolution (∼17.5 μm). The time required for a dose evaluation is less than a hundredth that required for radiochromic dye film measurements. The non-uniformity of the system has been eliminated by applying pixel-to-pixel correction factors. The measurable dose rate range using a 110 μm thick scintillator extends from ∼2000 down to ∼6 Gy h -1 . The prototype ICCD-scintillator system has been used in evaluation of the skin dose from some high-activity nuclear fuel fragments. The results agree within a few percentage with radiochromic dye film measurements for 1 cm 2 averaging areas. (authors)

  20. Agricultural measures to reduce radiation doses to man caused by severe nuclear accidents

    International Nuclear Information System (INIS)

    Dorp, F. van; Eleveld, R.; Frissel, M.J.

    1981-01-01

    Agricultural land and products may become contaminated after a severe nuclear accident. If radiation doses to man caused by the ingestion of contaminated agricultural products from such areas will be unacceptably high, measures to reduce this radiation dose will have to be taken. Radiation doses to man can be estimated by using models which describe quantitatively the transfer of radionuclides through the biosphere. The following processes and pathways are described in this study: accidental releases into atmospheric environments and subsequent nearby deposition; contamination of crops by direct deposition and the subsequent short term pathway (e.g. grass-cow-milk-man); contamination of soil and the subsequent long term pathway (e.g. soil-crop-man, soil-grass-cattle-milk/meat-man). Depending on the degree of contamination and on the estimated radiation doses to man, various measures are advised. (Auth.)

  1. Individual dose reconstruction among residents living in the vicinity of the Semipalatinsk nuclear test site using EPR spectroscopy of tooth enamel.

    Science.gov (United States)

    Ivannikov, A I; Zhumadilov, Zh; Gusev, B I; Miyazawa, Ch; Jiao, L; Skvortsov, V G; Stepanenko, V F; Takada, J; Hoshi, M

    2002-08-01

    Individual accumulated doses were determined by EPR spectroscopy of tooth enamel for 26 adult persons residing in territories adjacent to the Semipalatinsk Nuclear Test Site (SNTS). The absorbed dose values due to radiation from nuclear tests were obtained after subtracting the contribution of natural background radiation from the total accumulated dose. The determined dose values ranged up to 250 mGy, except for one person from Semipalatinsk city with a measured dose of 2.8 +/- 0.4 Gy. Increased dose values were determined for the individuals whose teeth were formed before 1962, the end of the atmospheric nuclear tests. These values were found to be significantly larger than those obtained for a group of younger residents of heavily exposed territories and the residents of territories not exposed to radioactive fallout. These increased dose values are consistent with those based on officially registered data for the Northeastern part of Kazakstan adjacent to SNTS, which was exposed to high levels of radioactive fallout from nuclear tests in period 1949-1962.

  2. Some effects of random dose measurement errors on analysis of atomic bomb survivor data

    International Nuclear Information System (INIS)

    Gilbert, E.S.

    1985-01-01

    The effects of random dose measurement errors on analyses of atomic bomb survivor data are described and quantified for several procedures. It is found that the ways in which measurement error is most likely to mislead are through downward bias in the estimated regression coefficients and through distortion of the shape of the dose-response curve. The magnitude of the bias with simple linear regression is evaluated for several dose treatments including the use of grouped and ungrouped data, analyses with and without truncation at 600 rad, and analyses which exclude doses exceeding 200 rad. Limited calculations have also been made for maximum likelihood estimation based on Poisson regression. 16 refs., 6 tabs

  3. Issues with using radiological exposures as a company performance measure in a low dose environment

    International Nuclear Information System (INIS)

    Wilkins, Richard I.

    2008-01-01

    Full text: Collective and maximum individual doses are two measures commonly used as an indicator for measuring Company performance. There is often an expectation for year on year improvements by optimisation of exposures through improved working methods and modernisation of facilities. Eventually a level of exposure can be reached that is no longer easy to measure which makes meaningful trend analysis difficult. The paper discusses the issues that arose at AWE where the majority of exposures are close the limit of detection for the TLD system used. It details the investigation that was carried out when recorded doses where observed to unexpectedly increase significantly. The paper shows the significant effect of a small change in the background radiation levels that are subtracted for each individual dose measurement. Also discussed is the effect of using TLD dosimeter readers that have undergone recent maintenance and are therefore assessing slightly increased exposures. Compounding the apparent increase in gamma dose a slight change in the manufacturing process for the plastic neutron film in the neutron dosimeters also gave an increased neutron exposure measurement which is detailed. The paper concludes with describing the changes that have been made to better ensure reproducibility of the exposure measurements so that any improvements in Company performance can be shown. It also questions the use of Collective Dose as a performance measure which is commonly misused across the industry. (author)

  4. SU-E-J-11: Measurement of Eye Lens Dose for Varian On-Board Imaging with Different CBCT Acquisition Techniques

    International Nuclear Information System (INIS)

    Deshpande, S; Dhote, D; Kumar, R; Thakur, K

    2015-01-01

    Purpose: To measure actual patient eye lens dose for different cone beam computed tomography (CBCT) acquisition protocol of Varian’s On Board Imagining (OBI) system using Optically Stimulated Luminescence (OSL) dosimeter and study the eye lens dose with patient geometry and distance of isocenter to the eye lens Methods: OSL dosimeter was used to measure eye lens dose of patient. OSL dosimeter was placed on patient forehead center during CBCT image acquisition to measure eye lens dose. For three different cone beam acquisition protocol (standard dose head, low dose head and high quality head) of Varian On-Board Imaging, eye lens doses were measured. Measured doses were correlated with patient geometry and distance between isocenter to eye lens. Results: Measured eye lens dose for standard dose head was in the range of 1.8 mGy to 3.2 mGy, for high quality head protocol dose was in range of 4.5mGy to 9.9 mGy whereas for low dose head was in the range of 0.3mGy to 0.7mGy. Dose to eye lens is depends upon position of isocenter. For posterioraly located tumor eye lens dose is less. Conclusion: From measured doses it can be concluded that by proper selection of imagining protocol and frequency of imaging, it is possible to restrict the eye lens dose below the new limit set by ICRP. However, undoubted advantages of imaging system should be counter balanced by careful consideration of imaging protocol especially for very intense imaging sequences for Adoptive Radiotherapy or IMRT

  5. Calorimetry for absorbed dose measurement at 1-4 MeV electron accelerators

    International Nuclear Information System (INIS)

    Miller, A.

    2000-01-01

    Calorimeters are used for dose measurement, calibration and intercomparisons at industrial electron accelerators, and their use at 10 MeV electron accelerators is well documented. The work under this research agreement concerns development of calorimeters for use at electron accelerators with energies in the range of 2-4 MeV. The dose range of the calorimeters is 3-40 kGy, and their temperature stability after irradiation was found to be sufficient for practical use in an industrial environment. Measurement uncertainties were determined to be 5% at k = 2. (author)

  6. Staff extremity doses in interventional radiology. Results of the ORAMED measurement campaign

    International Nuclear Information System (INIS)

    Nikodemová, D.; Brodecki, M.; Carinou, E.; Domienik, J.; Donadille, L.; Koukorava, C.; Krim, S.; Ruiz-López, N.; Sans-Merce, M.; Struelens, L.; Vanhavere, F.; Zaknoune, R.

    2011-01-01

    The introduction of interventional radiology (IR) procedures in the 20th century has demonstrated significant advantages over surgery procedures. As a result, their number is continuously rising in diagnostic, as well as, in therapy field and is connected with progress in highly sophisticated equipment used for these purposes. Nowadays, in the European countries more than 400 fluoroscopically guided IR procedures were identified with a 10–12% increase in the number of IR examinations every year (). Depending on the complexity of the different types of the interventions large differences in the radiation doses of the staff are observed. The staff that carries out IR procedures is likely to receive relatively high radiation doses, because IR procedures require the operator to remain close to the patient and close to the primary radiation beam. In spite of the fact that the operator is shielded by protective apron, the hands, eyes and legs remain practically unshielded. For this reason, one of the aims of the ORAMED project was to provide a set of standardized data on extremity doses for the personnel that are involved in IR procedures and to optimize their protection by evaluating the various factors that affect the doses. In the framework of work package 1 of the ORAMED project the impact of protective equipment, tube configuration and access routes were analyzed for the selected IR procedures. The position of maximum dose measured is also investigated. The results of the extremity doses in IR workplaces are presented in this study together with the influence of the above mentioned parameters on the doses. -- Highlights: ► We present a set of data on extremity doses for staff in selected interventional radiology procedures. ► We studied the influence of different parameters. ► The measured doses are analyzed according to the operators skill,his position during work, tube configuration, etc. ► Maximum doses recorded for all types of embolisation, in all

  7. Microdosimetry measurements with the RME-III on the space shuttle

    International Nuclear Information System (INIS)

    Hardy, K.; Golightly, M.J.; Atwell, W.; Quam, W.

    1994-01-01

    Since December 1988 (STS-27) the USAF Armstrong Laboratory, in conjunction with the NASA Space Radiation Analysis Group, has been conducting microdosimetry measurements on selected high-altitude, high-inclination Space Shuttle mission with the RME-III. The RME-III is a portable, self-contained, active dosimeter system featuring a three-channel tissue equivalent proportional counter (TEPC) which measures particle fluence and computes dose and dose equivalent at operator selected time intervals. The total accumulated absorbed dose and dose equivalent are displayed real time, while the data and the time of the interval dose readings are stored in memory modules for later analysis. Analysis of the time-resolved data permits correlation of the radiation exposure with geographic position, altitude, and spacecraft shielding and orientation. The RME-III has flown on 15 Shuttle missions to date and measurements are in good agreement with other dosimetry measurements made on the Shuttle

  8. Measurement and monitoring of entrance exposure dose rate in X-ray image intensifier television with dose rate control

    Energy Technology Data Exchange (ETDEWEB)

    Klein, J [Bezirkskrankenhaus Brandenburg (German Democratic Republic)

    1981-03-01

    For X-ray image intensifier television operation very low entrance dose rates (about 5.2 nA/kg) are stated and demanded, respectively. These required values are often manifold exceeded in practice so that a check seems to be necessary. It is shown and proved how these measurements can be performed with simple, generally available means of measurement in the radiological practice. For ZnCdS-image intensifiers should be considered that about 13 nA/kg for the large entrance size are not to be exceeded; for the CsI type lower values (factor 1.5) are practicable because of the twofold quantum absorption efficiency. Furthermore, some tests for a semiquantitative function check of the automatic dose rate control are proposed.

  9. User instructions for the DESCARTES environmental accumulation code

    International Nuclear Information System (INIS)

    Miley, T.B.; Eslinger, P.W.; Nichols, W.E.; Lessor, K.S.; Ouderkirk, S.J.

    1994-05-01

    The purpose of the Hanford Environmental Dose Reconstruction (HEDR) Project is to estimate the radiation dose that individuals could have received as a result of emissions since 1944 from the Hanford Site near Richland, Washington. The HEDR Project work is conducted under several technical and administrative tasks, among which is the Environmental Pathways and Dose Estimates task. The staff on this task have developed a suite of computer codes which are used to estimate doses to individuals in the public. This document contains the user instructions for the DESCARTES (Dynamic estimates of concentrations and Accumulated Radionuclides in Terrestrial Environments) suite of codes. In addition to the DESCARTES code, this includes two air data preprocessors, a database postprocessor, and several utility routines that are used to format input data needed for DESCARTES

  10. Cadmium and zinc accumulation in soybean: A threat to food safety?

    International Nuclear Information System (INIS)

    Shute, Tracy; Macfie, Sheila M.

    2006-01-01

    A greenhouse study was conducted to quantify cadmium and zinc accumulated by soybean (Glycine max (L.) Merr.) when the metals were supplied separately and together. The highest dose of cadmium (100 mg/kg) reduced plant height and dry weight (down to 40% and 34% of control, respectively); the highest dose of zinc (2000 mg/kg) reduced plant height to 55% of control and dry weight to 70% of control. With both metals present, the plants were approximately the same size as those treated with cadmium only. The concentration of cadmium in the roots was unaffected by zinc. In other tissues, the effect of zinc on the accumulation of cadmium depended on the doses provided. At low doses, the addition of zinc reduced the concentration of cadmium in aboveground tissues to 40-50% of that found in plants exposed to cadmium only. However, when applied in high doses, the presence of zinc in cadmium-contaminated soils increased the uptake and accumulation of cadmium in aboveground tissues by up to 42%. In contrast, at high doses, the presence of cadmium in zinc-contaminated soil resulted in approximately 35% lower concentrations of zinc in all tissues. At a lower dose, cadmium had no effect on concentration of zinc in the plant tissues. The effects of high doses of one metal on the uptake of the other metal can be partially explained by the effects of one metal on the bioavailability of the other metal. In soils to which only one metal was added, bioavailable cadmium was 70-80% of the total cadmium, and bioavailable zinc was 50-70% of the total zinc. When both metals were added to the soil, 80-100% of the cadmium and 46-60% of the zinc were bioavailable. Concentrations of both metals were highest in root tissues (10-fold higher for cadmium, and up to 2-fold higher for zinc). Although relatively little cadmium was translocated to pods and seeds, the seeds of all plants (including those from control and zinc-treated plants) had concentrations of cadmium 3-4 times above the limit of 0

  11. Dose in the uterus of a woman, with three months of pregnancy, due to the {sup 131} I accumulated in her thyroid gland; Dosis en el utero de una mujer, con tres meses de embarazo, debida la {sup 131} I acumulado en su glandula tiroides

    Energy Technology Data Exchange (ETDEWEB)

    Vega C, H.R.; Manzanares A, E.; Hernandez D, V.M.; Arcos P, A. [Unidades Academicas de Estudios Nucleares e Ingenieria Electrica, Universidad Autonoma de Zacatecas, C. Cipres 10, Fracc. La Penuela, 98068 Zacatecas (Mexico)]. e-mail: fermineutron@yahoo.com

    2006-07-01

    In this study the absorbed dose by the uterus of a woman with three months of pregnancy to who was applied a dose of {sup 131} I that was accumulated in the thyroid gland is determined. The absorbed dose was obtained by means of Monte Carlo calculations developing a detailed three-dimensional model of the pregnant one, where they have been included most of the organs. The absorbed dose also was calculated by means of a simple procedure. To verify the calculated results it was carried out an experiment where was constructed a phantom of the neck, in this was included the thyroid with {sup 131} I and the exposure was measured at different distances of the neck; this was related with the dose. Of the Monte Carlo calculation is obtained that for each mCi of {sup 131} I that is retained in the mother's thyroid, the uterus absorbs a dose of 6.80 E(-11) Gy. When comparing the results, it was found that the simple calculation throws a result 29 times superior to that of the dose obtained by means of Monte Carlo. When applying a correction for the effect of the absorption of the gamma photons by the mother's body an absorbed dose in the uterus was obtained that is 0.16 times superior to the Monte Carlo calculation. Of the experimental phase it is verified that the values calculated by means of the simple method are equal to those experimentally measured. (Author)

  12. Measurement with total scatter calibrate factor at different depths in the calculation of prescription dose

    International Nuclear Information System (INIS)

    Li Lijun; Zhu Haijun; Zhang Xinzhong; Li Feizhou; Song Hongyu

    2004-01-01

    Objective: To evaluate the method of measurement of total scatter calibrate factor (Sc, p). Methods: To measure the Sc, p at different depths on central axis of 6MV, 15MV photon beams through different ways. Results: It was found that the measured data of Sc, p changed with the different depths to a range of 1% - 7%. Using the direct method, the Sc, p measured depth should be the same as the depth in dose normalization point of the prescription dose. If the Sc, p (fsz, d) was measured at the other depths, it could be obtained indirectly by the calculation formula. Conclusions: The Sc, p in the prescription dose can be obtained either by the direct measure method or the indirect calculation formula. But emphasis should be laid on the proper measure depth. (authors)

  13. Measurements of surgeons' exposure to ionizing radiation dose during intraoperative use of C-arm fluoroscopy.

    Science.gov (United States)

    Lee, Kisung; Lee, Kyoung Min; Park, Moon Seok; Lee, Boram; Kwon, Dae Gyu; Chung, Chin Youb

    2012-06-15

    Measurement of radiation dose from C-arm fluoroscopy during a simulated intraoperative use in spine surgery. OBJECTIVE.: To investigate scatter radiation doses to specific organs of surgeons during intraoperative use of C-arm fluoroscopy in spine surgery and to provide practical intraoperative guidelines. There have been studies that reported the radiation dose of C-arm fluoroscopy in various procedures. However, radiation doses to surgeons' specific organs during spine surgery have not been sufficiently examined, and the practical intraoperative radioprotective guidelines have not been suggested. Scatter radiation dose (air kerma rate) was measured during the use of a C-arm on an anthropomorphic chest phantom on an operating table. Then, a whole body anthropomorphic phantom was located besides the chest phantom to simulate a surgeon, and scatter radiation doses to specific organs (eye, thyroid, breast, and gonads) and direct radiation dose to the surgeon's hand were measured using 4 C-arm configurations (standard, inverted, translateral, and tube translateral). The effects of rotating the surgeon's head away from the patient and of a thyroid shield were also evaluated. Scatter radiation doses decreased as distance from the patient increased during C-arm fluoroscopy use. The standard and translateral C-arm configurations caused lower scatter doses to sensitive organs than inverted and tube translateral configurations. Scatter doses were highest for breast and lowest for gonads. The use of a thyroid shield and rotating the surgeon's head away from the patient reduced scatter radiation dose to the surgeon's thyroid and eyes. The direct radiation dose was at least 20 times greater than scatter doses to sensitive organs. The following factors could reduce radiation exposure during intraoperative use of C-arm; (1) distance from the patient, (2) C-arm configuration, (3) radioprotective equipments, (4) rotating the surgeons' eyes away from the patient, and (5) avoiding

  14. Review of techniques and detectors used in instruments for field measurement of β doses and dose rates

    International Nuclear Information System (INIS)

    Jones, A.R.

    1984-01-01

    Generally, field measurements are required to assess the hazard from β-rays before personnel are allowed to occupy a working space or perform a task. Occasionally, the measurements are required for an assessment after a β-ray exposure is suspected to have occurred. With these uses of field instruments in mind, the following detectors and associated techniques will be discussed in terms of the measurement principles, advantages, and limitations: 1) thin-walled ion chambers (sometimes in combination with thick-walled ones or with covers thick enough to prevent penetration of β-particles); 2) thin scintillators, nearly tissue equivalent, to provide a detector analogous to skin; 3) scintillators, thick enough to absorb all the energy of the β-particles. Circuitry is required to count pulses according to size to permit calculation of dose or dose rate; 4) silicon diodes with thin detection layers operated as photocurrent generators; 5) silicon diodes, reversed biassed, with pulses counted according to size; 6) simple pulse counters (e.g., GM counters or silicon diodes with thin windows)

  15. In-phantom measurement of absorbed dose to water in medium energy x-ray beams

    International Nuclear Information System (INIS)

    Hohlfeld, K.

    1996-01-01

    Absorbed dose values in a water phantom derived by the formalism of the IAEA Code of Practice of Absorbed Dose Determination in Photon and Electron Beams are a few per cent higher than those based on the procedure following e.g. ICRU Report 23. The maximum deviation exceeds 10% at 100 kV tube potential. The correction factor needed to take into account the differences at the calibration in terms of air kerma free in air and at the measurement in the water phantom can be determined in different ways: In comparing the result of the absorbed dose measurement by means of the ionization chambers with an other, preferably fundamental method of measurement of absorbed dose in the water phantom or by evaluating all component parts of the correction factor separately. The values of the perturbation correction factor in the IAEA Code were determined in the former way by comparing against a graphite extrapolation chamber. A review is given on a recent re-evaluation using former values of the extrapolation chamber measurements and on new determinations using an absorbed dose water calorimeter, a method based on calculated and measured air kerma values and a method of combining the component factors to the overall correction factor. Recent results achieved by the different methods are compared and a change of the data of the IAEA Code is recommended. (author). 31 refs, 14 figs, 3 tabs

  16. Measurement of dose received in knee joint x-ray examination

    International Nuclear Information System (INIS)

    Abashar, Basamat Musa Hajo

    2014-11-01

    Diagnostic x-rays examinations play an important role in the health care of the population. These examinations may involve significant irradiation of the patient and probably represent the largest man-made source of radiation exposure for the population. This study was performed in Khartoum Teaching Hospital in period of January to June 2014. This study performed to assess the effective dose (ED) received in knee joint radiographic examination and to analyze dose (ed) received in knee joint radiographic examination and to analyze effective dose distribution among radiological departments under study. The study was performed in Khartoum Teaching Hospital, covering two x-ray units and a sample of 50 patients. The following parameters were recorded age, weight, height, body mass ines (BMI) derived from weight (Kg) and (Height (M)) and (height (m)) and exposure factors. The dose was measured for knee joint x-rays examination. For effective dose calculation, the entrance surface dose (ESD) values were estimated from the x-ray tube output parameters for knee joint Ap and lateral examinations. The ED values were then calculated from the obtained ESD values using IAEA calculation methods. Effective doses were then calculated from energy imparted using ED conversion factors proposed by IAEA. The results of ED values calculated showed that patient exposure were within the normal range of exposure. The mean ED values calculated were( 2.49 + 0.03) and (5.60 + 0.22) milli Grey for knee joint AP and lateral examinations, respectively, Further studies are recommended with more number of patients and using more two modalities for comparison.(Author)

  17. Thyroid doses in Belarus resulting from the Chernobyl accident: comparison of the estimates based on direct thyroid measurements and on measurements of 131I in milk

    International Nuclear Information System (INIS)

    Shinkarev, Sergey; Gavrilin, Yury; Khrouch, Valery; Savkin, Mikhail; Bouville, Andre; Luckyanov, Nicholas

    2008-01-01

    A substantial increase of childhood cancer cases observed in Belarus, Ukraine and Russia after the Chernobyl accident has been associated with thyroid exposure to radio iodines following the accident. A large number of direct thyroid measurements (i.e. measurement of the exposure rate near the thyroid of the subject)were conducted in Belarus during a few weeks after the accident. Individual thyroid doses based on results of the direct thyroid measurements were estimated for about 126,000 Belarusian residents and settlement-average thyroid doses for adults were calculated for 426 contaminated settlements in Gomel and Mogilev Oblasts. Another set of settlement-average thyroid doses for adults was estimated based on results of activity measurements in milk samples for 28 settlements (with not less than 2 spectrometric measurements) and 155 settlements (with not less than 5 total beta-activity measurements) in Gomel and Mogilev Oblasts. Concentrations of 131 I in milk were derived from these measurements. In the estimation of this set of thyroid doses, it was assumed that adults consumed 0.5 L d -1 of milk locally produced. The two sets of dose estimates were compared for 47 settlements, for which simultaneously were available a dose estimate based on thyroid measurements and a dose estimate based either on spectrometric or radiometric milk data. The settlement average thyroid doses based on milk activity measurements were higher than those based on direct thyroid measurements by a factor of 1.8 for total beta-activity measurements (30 settlements were compared) and by a factor of 2.4 for spectrometric measurements (17 settlements). This systematic difference can be explained by overestimation of the milk consumption rate used in the calculation of the milk-based thyroid doses and/or by application of individual countermeasures by people. (author)

  18. Accumulating Data to Optimally Predict Obesity Treatment (ADOPT) Core Measures: Psychosocial Domain.

    Science.gov (United States)

    Sutin, Angelina R; Boutelle, Kerri; Czajkowski, Susan M; Epel, Elissa S; Green, Paige A; Hunter, Christine M; Rice, Elise L; Williams, David M; Young-Hyman, Deborah; Rothman, Alexander J

    2018-04-01

    Within the Accumulating Data to Optimally Predict obesity Treatment (ADOPT) Core Measures Project, the psychosocial domain addresses how psychosocial processes underlie the influence of obesity treatment strategies on weight loss and weight maintenance. The subgroup for the psychosocial domain identified an initial list of high-priority constructs and measures that ranged from relatively stable characteristics about the person (cognitive function, personality) to dynamic characteristics that may change over time (motivation, affect). This paper describes (a) how the psychosocial domain fits into the broader model of weight loss and weight maintenance as conceptualized by ADOPT; (b) the guiding principles used to select constructs and measures for recommendation; (c) the high-priority constructs recommended for inclusion; (d) domain-specific issues for advancing the science; and (e) recommendations for future research. The inclusion of similar measures across trials will help to better identify how psychosocial factors mediate and moderate the weight loss and weight maintenance process, facilitate research into dynamic interactions with factors in the other ADOPT domains, and ultimately improve the design and delivery of effective interventions. © 2018 The Obesity Society.

  19. Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBα/β activation in aryl hydrocarbon receptor-elicited hepatotoxicity

    Energy Technology Data Exchange (ETDEWEB)

    Fader, Kelly A.; Nault, Rance [Department of Biochemistry & Molecular Biology, Michigan State University, East Lansing, MI 48824 (United States); Institute for Integrative Toxicology, Michigan State University, East Lansing, MI 48824 (United States); Kirby, Mathew P.; Markous, Gena [Department of Biochemistry & Molecular Biology, Michigan State University, East Lansing, MI 48824 (United States); Matthews, Jason [Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo 0316 (Norway); Zacharewski, Timothy R., E-mail: tzachare@msu.edu [Department of Biochemistry & Molecular Biology, Michigan State University, East Lansing, MI 48824 (United States); Institute for Integrative Toxicology, Michigan State University, East Lansing, MI 48824 (United States)

    2017-04-15

    Persistent aryl hydrocarbon receptor (AhR) agonists elicit dose-dependent hepatic lipid accumulation, oxidative stress, inflammation, and fibrosis in mice. Iron (Fe) promotes AhR-mediated oxidative stress by catalyzing reactive oxygen species (ROS) production. To further characterize the role of Fe in AhR-mediated hepatotoxicity, male C57BL/6 mice were orally gavaged with sesame oil vehicle or 0.01–30 μg/kg 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) every 4 days for 28 days. Duodenal epithelial and hepatic RNA-Seq data were integrated with hepatic AhR ChIP-Seq, capillary electrophoresis protein measurements, and clinical chemistry analyses. TCDD dose-dependently repressed hepatic expression of hepcidin (Hamp and Hamp2), the master regulator of systemic Fe homeostasis, resulting in a 2.6-fold increase in serum Fe with accumulating Fe spilling into urine. Total hepatic Fe levels were negligibly increased while transferrin saturation remained unchanged. Furthermore, TCDD elicited dose-dependent gene expression changes in heme biosynthesis including the induction of aminolevulinic acid synthase 1 (Alas1) and repression of uroporphyrinogen decarboxylase (Urod), leading to a 50% increase in hepatic hemin and a 13.2-fold increase in total urinary porphyrins. Consistent with this heme accumulation, differential gene expression suggests that heme activated BACH1 and REV-ERBα/β, causing induction of heme oxygenase 1 (Hmox1) and repression of fatty acid biosynthesis, respectively. Collectively, these results suggest that Hamp repression, Fe accumulation, and increased heme levels converge to promote oxidative stress and the progression of TCDD-elicited hepatotoxicity. - Highlights: • TCDD represses hepatic hepcidin expression, leading to systemic iron overloading. • Dysregulation of heme biosynthesis is consistent with heme and porphyrin accumulation. • Heme-activated REV-ERBα/β repress circadian-regulated hepatic lipid metabolism. • Disruption of iron

  20. Development of a synthetic single crystal diamond dosimeter for dose measurement of clinical proton beams

    Science.gov (United States)

    Moignier, Cyril; Tromson, Dominique; de Marzi, Ludovic; Marsolat, Fanny; García Hernández, Juan Carlos; Agelou, Mathieu; Pomorski, Michal; Woo, Romuald; Bourbotte, Jean-Michel; Moignau, Fabien; Lazaro, Delphine; Mazal, Alejandro

    2017-07-01

    The scope of this work was to develop a synthetic single crystal diamond dosimeter (SCDD-Pro) for accurate relative dose measurements of clinical proton beams in water. Monte Carlo simulations were carried out based on the MCNPX code in order to investigate and reduce the dose curve perturbation caused by the SCDD-Pro. In particular, various diamond thicknesses were simulated to evaluate the influence of the active volume thickness (e AV) as well as the influence of the addition of a front silver resin (250 µm in thickness in front of the diamond crystal) on depth-dose curves. The simulations indicated that the diamond crystal alone, with a small e AV of just 5 µm, already affects the dose at Bragg peak position (Bragg peak dose) by more than 2% with respect to the Bragg peak dose deposited in water. The optimal design that resulted from the Monte Carlo simulations consists of a diamond crystal of 1 mm in width and 150 µm in thickness with the front silver resin, enclosed by a water-equivalent packaging. This design leads to a deviation between the Bragg peak dose from the full detector modeling and the Bragg peak dose deposited in water of less than 1.2%. Based on those optimizations, an SCDD-Pro prototype was built and evaluated in broad passive scattering proton beams. The experimental evaluation led to probed SCDD-Pro repeatability, dose rate dependence and linearity, that were better than 0.2%, 0.4% (in the 1.0-5.5 Gy min-1 range) and 0.4% (for dose higher than 0.05 Gy), respectively. The depth-dose curves in the 90-160 MeV energy range, measured with the SCDD-Pro without applying any correction, were in good agreement with those measured using a commercial IBA PPC05 plane-parallel ionization chamber, differing by less than 1.6%. The experimental results confirmed that this SCDD-Pro is suitable for measurements with standard electrometers and that the depth-dose curve perturbation is negligible, with no energy dependence and no significant dose rate

  1. Mass balance re-analysis of Findelengletscher, Switzerland; benefits of extensive snow accumulation measurements

    Directory of Open Access Journals (Sweden)

    Leo eSold

    2016-02-01

    Full Text Available A re-analysis is presented here of a 10-year mass balance series at Findelengletscher, a temperate mountain glacier in Switzerland. Calculating glacier-wide mass balance from the set of glaciological point balance observations using conventional approaches, such as the profile or contour method, resulted in significant deviations from the reference value given by the geodetic mass change over a five-year period. This is attributed to the sparsity of observations at high elevations and to the inability of the evaluation schemes to adequately estimate accumulation in unmeasured areas. However, measurements of winter mass balance were available for large parts of the study period from snow probings and density pits. Complementary surveys by helicopter-borne ground-penetrating radar (GPR were conducted in three consecutive years. The complete set of seasonal observations was assimilated using a distributed mass balance model. This model-based extrapolation revealed a substantial mass loss at Findelengletscher of -0.43m w.e. a^-1 between 2004 and 2014, while the loss was less pronounced for its former tributary, Adlergletscher (-0.30m w.e. a^-1. For both glaciers, the resulting time series were within the uncertainty bounds of the geodetic mass change. We show that the model benefited strongly from the ability to integrate seasonal observations. If no winter mass balance measurements were available and snow cover was represented by a linear precipitation gradient, the geodetic mass balance was not matched. If winter balance measurements by snow probings and snow density pits were taken into account, the model performance was substantially improved but still showed a significant bias relative to the geodetic mass change. Thus the excellent agreement of the model-based extrapolation with the geodetic mass change was owed to an adequate representation of winter accumulation distribution by means of extensive GPR measurements.

  2. Total-dose hardness assurance for low earth orbit

    International Nuclear Information System (INIS)

    Maurer, R.H.; Suter, J.J.

    1987-01-01

    The Low Earth Orbit radiation environment has two significant characteristics that make laboratory simulation exposures difficult: (1) a low dose rate and (2) many cycles of low dose accumulation followed by dose-free annealing. Hardness assurance considerations for this environment are discussed and related to data from the testing of Advanced Low Power Schottky and High-speed CMOS devices

  3. Factors influencing the cardiac MIBG accumulation

    International Nuclear Information System (INIS)

    Takatsu, Hisato; Fujiwara, Hisayoshi

    1997-01-01

    Following factors possibly influencing the cardiac MIBG accumulation were examined mainly in mice. 1. The specific activity of the MIBG (meta-iodo-benzyl guanidine) on the neuronal and non-neuronal fractions. 2. Motor restriction stress on MIBG accumulation and washout. 3. Loading and restriction of sodium chloride on the accumulation and effect of suppression of renin-angiotensin system. 4. Examinations in Dahl rats. 125I- or 131I-MIBG was intravenously administered to mice at 74 kBq. At 30 min or 4 hr after administration, mice were sacrificed and their left ventricles were dissected out for measurement of radioactivity in a liquid scintillation counter. Salt-sensitive and -resistant Dahl rats were given with 37 MBq of 123I-MIBG and cardiac radioactivity was measured externally for calculation of washout. Factors examined were found highly correlated with the accumulation of MIBG and measurement of its washout was considered useful for evaluating sympathetic activity. (K.H.)

  4. Basic evaluation of signal transmission in a real-time internal radiation dose measurement system

    International Nuclear Information System (INIS)

    Shinohe, K.; Takura, T.; Sato, F.; Matsuki, H.; Yamada, S.; Sato, T.

    2009-01-01

    In radiation therapy, excessive exposure to radiation occurs because the dose actually delivered to the tumor is not known. As a result, a patient suffers from side effects. To solve this problem, a system is needed in which the delivered dose is measured inside the body and the dose data are transmitted from inside to outside of the body during radiation therapy. If such a system is realized, it will be possible to treat cancer safely and effectively. The proposed real-time internal radiation dose measurement system consists of an implantable dosimeter, a wireless communication system, and a wireless feeding system. In this study, a wireless communication system that uses magnetic fields was investigated. As a result, a communication distance of 200 mm was obtained. It was confirmed that radiation dose data could be transmitted outside the body when the communication distance is the required 200 mm. (author)

  5. Estimating average glandular dose by measuring glandular rate in mammograms

    International Nuclear Information System (INIS)

    Goto, Sachiko; Azuma, Yoshiharu; Sumimoto, Tetsuhiro; Eiho, Shigeru

    2003-01-01

    The glandular rate of the breast was objectively measured in order to calculate individual patient exposure dose (average glandular dose) in mammography. By employing image processing techniques and breast-equivalent phantoms with various glandular rate values, a conversion curve for pixel value to glandular rate can be determined by a neural network. Accordingly, the pixel values in clinical mammograms can be converted to the glandular rate value for each pixel. The individual average glandular dose can therefore be calculated using the individual glandular rates on the basis of the dosimetry method employed for quality control in mammography. In the present study, a data set of 100 craniocaudal mammograms from 50 patients was used to evaluate our method. The average glandular rate and average glandular dose of the data set were 41.2% and 1.79 mGy, respectively. The error in calculating the individual glandular rate can be estimated to be less than ±3%. When the calculation error of the glandular rate is taken into consideration, the error in the individual average glandular dose can be estimated to be 13% or less. We feel that our method for determining the glandular rate from mammograms is useful for minimizing subjectivity in the evaluation of patient breast composition. (author)

  6. Measurement of dose rates and Monte Carlo analysis of neutrons in a spent-fuel shipping vessel

    International Nuclear Information System (INIS)

    Ueki, K.; Namito, Y.; Fuse, T.

    1986-01-01

    On-board experiments were carried out in a spent-fuel shipping vessel, the Pacific Swan, in which 13 casks of TN-12A and Excellox 3 were loaded in five holds, and neutron and gamma-ray dose rates were measured on the hatch covers of the holds. Before shipping those casks, dose rates were also measured on the cask surfaces, one by one, to eliminate radiation from other casks. The Monte Carlo coupling technique was employed successfully to analyze the measured neutron dose rate distributions in the spent-fuel shipping vessel. Through this study, the Monte Carlo coupling code system, MORSE-CG/CASK-VESSEL, on which the MORSE-CG code was based, was established. The agreement between the measured and the calculated neutron dose rates on the TN-12A cask surface was quite satisfactory. The calculated neutron dose rates agreed with the measured values within a factor of 1.5 on the hold 3 hatch cover and within a factor of 2 on the hold 5 hatch cover in which the concrete shield was fixed in the Pacific Swan

  7. Comparison of measured and estimated maximum skin doses during CT fluoroscopy lung biopsies

    Energy Technology Data Exchange (ETDEWEB)

    Zanca, F., E-mail: Federica.Zanca@med.kuleuven.be [Department of Radiology, Leuven University Center of Medical Physics in Radiology, UZ Leuven, Herestraat 49, 3000 Leuven, Belgium and Imaging and Pathology Department, UZ Leuven, Herestraat 49, Box 7003 3000 Leuven (Belgium); Jacobs, A. [Department of Radiology, Leuven University Center of Medical Physics in Radiology, UZ Leuven, Herestraat 49, 3000 Leuven (Belgium); Crijns, W. [Department of Radiotherapy, UZ Leuven, Herestraat 49, 3000 Leuven (Belgium); De Wever, W. [Imaging and Pathology Department, UZ Leuven, Herestraat 49, Box 7003 3000 Leuven, Belgium and Department of Radiology, UZ Leuven, Herestraat 49, 3000 Leuven (Belgium)

    2014-07-15

    Purpose: To measure patient-specific maximum skin dose (MSD) associated with CT fluoroscopy (CTF) lung biopsies and to compare measured MSD with the MSD estimated from phantom measurements, as well as with the CTDIvol of patient examinations. Methods: Data from 50 patients with lung lesions who underwent a CT fluoroscopy-guided biopsy were collected. The CT protocol consisted of a low-kilovoltage (80 kV) protocol used in combination with an algorithm for dose reduction to the radiology staff during the interventional procedure, HandCare (HC). MSD was assessed during each intervention using EBT2 gafchromic films positioned on patient skin. Lesion size, position, total fluoroscopy time, and patient-effective diameter were registered for each patient. Dose rates were also estimated at the surface of a normal-size anthropomorphic thorax phantom using a 10 cm pencil ionization chamber placed at every 30°, for a full rotation, with and without HC. Measured MSD was compared with MSD values estimated from the phantom measurements and with the cumulative CTDIvol of the procedure. Results: The median measured MSD was 141 mGy (range 38–410 mGy) while the median cumulative CTDIvol was 72 mGy (range 24–262 mGy). The ratio between the MSD estimated from phantom measurements and the measured MSD was 0.87 (range 0.12–4.1) on average. In 72% of cases the estimated MSD underestimated the measured MSD, while in 28% of the cases it overestimated it. The same trend was observed for the ratio of cumulative CTDIvol and measured MSD. No trend was observed as a function of patient size. Conclusions: On average, estimated MSD from dose rate measurements on phantom as well as from CTDIvol of patient examinations underestimates the measured value of MSD. This can be attributed to deviations of the patient's body habitus from the standard phantom size and to patient positioning in the gantry during the procedure.

  8. Comparison of measured and estimated maximum skin doses during CT fluoroscopy lung biopsies

    International Nuclear Information System (INIS)

    Zanca, F.; Jacobs, A.; Crijns, W.; De Wever, W.

    2014-01-01

    Purpose: To measure patient-specific maximum skin dose (MSD) associated with CT fluoroscopy (CTF) lung biopsies and to compare measured MSD with the MSD estimated from phantom measurements, as well as with the CTDIvol of patient examinations. Methods: Data from 50 patients with lung lesions who underwent a CT fluoroscopy-guided biopsy were collected. The CT protocol consisted of a low-kilovoltage (80 kV) protocol used in combination with an algorithm for dose reduction to the radiology staff during the interventional procedure, HandCare (HC). MSD was assessed during each intervention using EBT2 gafchromic films positioned on patient skin. Lesion size, position, total fluoroscopy time, and patient-effective diameter were registered for each patient. Dose rates were also estimated at the surface of a normal-size anthropomorphic thorax phantom using a 10 cm pencil ionization chamber placed at every 30°, for a full rotation, with and without HC. Measured MSD was compared with MSD values estimated from the phantom measurements and with the cumulative CTDIvol of the procedure. Results: The median measured MSD was 141 mGy (range 38–410 mGy) while the median cumulative CTDIvol was 72 mGy (range 24–262 mGy). The ratio between the MSD estimated from phantom measurements and the measured MSD was 0.87 (range 0.12–4.1) on average. In 72% of cases the estimated MSD underestimated the measured MSD, while in 28% of the cases it overestimated it. The same trend was observed for the ratio of cumulative CTDIvol and measured MSD. No trend was observed as a function of patient size. Conclusions: On average, estimated MSD from dose rate measurements on phantom as well as from CTDIvol of patient examinations underestimates the measured value of MSD. This can be attributed to deviations of the patient's body habitus from the standard phantom size and to patient positioning in the gantry during the procedure

  9. Comparative study of radiation damage accumulation in Cu and Fe

    International Nuclear Information System (INIS)

    Caturla, M.J.; Soneda, N.; Alonso, E.; Wirth, B.D.; Diaz de la Rubia, T.; Perlado, J.M.

    2000-01-01

    Bcc and fcc metals exhibit significant differences in behavior when exposed to neutron or heavy ion irradiation. Transmission electron microscopy (TEM) observations reveal that damage in the form of stacking fault tetrahedra (SFT) is visible in copper irradiated to very low doses, but that no damage is visible in iron irradiated to the same total dose. In order to understand and quantify this difference in behavior, we have simulated damage production and accumulation in fcc Cu and bcc Fe. We use 20 keV primary knock-on atoms (PKAs) at a homologous temperature of 0.25 of the melting point. The primary damage state was calculated using molecular dynamics (MD) with empirical, embedded-atom interatomic potentials. Damage accumulation was modeled using a kinetic Monte Carlo (kMC) algorithm to follow the evolution of all defects produced in the cascades. The diffusivities and binding energies of defects are input data for this simulation and were either extracted from experiments, the literature, or calculated using MD. MD simulations reveal that vacancy clusters are produced within the cascade core in the case of copper. In iron, most of the vacancies do not cluster during cooling of the cascade core and are available for diffusion. In addition, self-interstitial atom (SIA) clusters are produced in copper cascades but those observed in iron are smaller in number and size. The combined MD/kMC simulations reveal that the visible cluster densities obtained as a function of dose are at least one order of magnitude lower in Fe than in Cu. We compare the results with experimental measurements of cluster density and find excellent agreement between the simulations and experiments when small interstitial clusters are considered to be mobile as suggested by recent MD simulations

  10. Radiographic film dosimetry of proton beams for depth‐dose constancy check and beam profile measurement

    Science.gov (United States)

    Teran, Anthony; Ghebremedhin, Abiel; Johnson, Matt; Patyal, Baldev

    2015-01-01

    Radiographic film dosimetry suffers from its energy dependence in proton dosimetry. This study sought to develop a method of measuring proton beams by the film and to evaluate film response to proton beams for the constancy check of depth dose (DD). It also evaluated the film for profile measurements. To achieve this goal, from DDs measured by film and ion chamber (IC), calibration factors (ratios of dose measured by IC to film responses) as a function of depth in a phantom were obtained. These factors imply variable slopes (with proton energy and depth) of linear characteristic curves that relate film response to dose. We derived a calibration method that enables utilization of the factors for acquisition of dose from film density measured at later dates by adapting to a potentially altered processor condition. To test this model, the characteristic curve was obtained by using EDR2 film and in‐phantom film dosimetry in parallel with a 149.65 MeV proton beam, using the method. An additional validation of the model was performed by concurrent film and IC measurement perpendicular to the beam at various depths. Beam profile measurements by the film were also evaluated at the center of beam modulation. In order to interpret and ascertain the film dosimetry, Monte Carlos simulation of the beam was performed, calculating the proton fluence spectrum along depths and off‐axis distances. By multiplying respective stopping powers to the spectrum, doses to film and water were calculated. The ratio of film dose to water dose was evaluated. Results are as follows. The characteristic curve proved the assumed linearity. The measured DD approached that of IC, but near the end of the spread‐out Bragg peak (SOBP), a spurious peak was observed due to the mismatch of distal edge between the calibration and measurement films. The width of SOBP and the proximal edge were both reproducible within a maximum of 5 mm; the distal edge was reproducible within 1 mm. At 5 cm depth, the

  11. Measuring uncertainty in dose delivered to the cochlea due to setup error during external beam treatment of patients with cancer of the head and neck

    Energy Technology Data Exchange (ETDEWEB)

    Yan, M.; Lovelock, D.; Hunt, M.; Mechalakos, J.; Hu, Y.; Pham, H.; Jackson, A., E-mail: jacksona@mskcc.org [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York 10065 (United States)

    2013-12-15

    Purpose: To use Cone Beam CT scans obtained just prior to treatments of head and neck cancer patients to measure the setup error and cumulative dose uncertainty of the cochlea. Methods: Data from 10 head and neck patients with 10 planning CTs and 52 Cone Beam CTs taken at time of treatment were used in this study. Patients were treated with conventional fractionation using an IMRT dose painting technique, most with 33 fractions. Weekly radiographic imaging was used to correct the patient setup. The authors used rigid registration of the planning CT and Cone Beam CT scans to find the translational and rotational setup errors, and the spatial setup errors of the cochlea. The planning CT was rotated and translated such that the cochlea positions match those seen in the cone beam scans, cochlea doses were recalculated and fractional doses accumulated. Uncertainties in the positions and cumulative doses of the cochlea were calculated with and without setup adjustments from radiographic imaging. Results: The mean setup error of the cochlea was 0.04 ± 0.33 or 0.06 ± 0.43 cm for RL, 0.09 ± 0.27 or 0.07 ± 0.48 cm for AP, and 0.00 ± 0.21 or −0.24 ± 0.45 cm for SI with and without radiographic imaging, respectively. Setup with radiographic imaging reduced the standard deviation of the setup error by roughly 1–2 mm. The uncertainty of the cochlea dose depends on the treatment plan and the relative positions of the cochlea and target volumes. Combining results for the left and right cochlea, the authors found the accumulated uncertainty of the cochlea dose per fraction was 4.82 (0.39–16.8) cGy, or 10.1 (0.8–32.4) cGy, with and without radiographic imaging, respectively; the percentage uncertainties relative to the planned doses were 4.32% (0.28%–9.06%) and 10.2% (0.7%–63.6%), respectively. Conclusions: Patient setup error introduces uncertainty in the position of the cochlea during radiation treatment. With the assistance of radiographic imaging during setup

  12. Measurement of local dose rates in controlled areas of nuclear power plants. Version 6/85

    International Nuclear Information System (INIS)

    1985-01-01

    Local dose rate measurements according to this regulation, serve the following purposes: Development of preventive measures for radiation protection with respect to maintenance and modifications in controlled areas, e.g. determination of individual measures for personnel protection, development of flow charts and dose rate estimates; monitoring of the personnel's location of activity within the controlled area, including determination of time-dependence of local dose rates and determination of immediate radiation protection measures required; limitation and identification of controlled areas. Such measurements are performed to ensure that the principles of radiation protection as stated in Art. 28 (1) of the Radiation Protection Ordinance with respect to external radiation exposure of the personnel, and the requirements of Art. 61 (1) of the Radiation Protection Ordinance relating to controlled areas are met and the limitation and identification of controlled areas as prescribed in Art 57 (1) of the Radiation Protection Ordinance can be performed. They are not used to determine body doses as per Art. 63 of the Radiation Protection Ordinance. (orig./HP) [de

  13. The Accumulating Data to Optimally Predict Obesity Treatment (ADOPT) Core Measures Project: Rationale and Approach.

    Science.gov (United States)

    MacLean, Paul S; Rothman, Alexander J; Nicastro, Holly L; Czajkowski, Susan M; Agurs-Collins, Tanya; Rice, Elise L; Courcoulas, Anita P; Ryan, Donna H; Bessesen, Daniel H; Loria, Catherine M

    2018-04-01

    Individual variability in response to multiple modalities of obesity treatment is well documented, yet our understanding of why some individuals respond while others do not is limited. The etiology of this variability is multifactorial; however, at present, we lack a comprehensive evidence base to identify which factors or combination of factors influence treatment response. This paper provides an overview and rationale of the Accumulating Data to Optimally Predict obesity Treatment (ADOPT) Core Measures Project, which aims to advance the understanding of individual variability in response to adult obesity treatment. This project provides an integrated model for how factors in the behavioral, biological, environmental, and psychosocial domains may influence obesity treatment responses and identify a core set of measures to be used consistently across adult weight-loss trials. This paper provides the foundation for four companion papers that describe the core measures in detail. The accumulation of data on factors across the four ADOPT domains can inform the design and delivery of effective, tailored obesity treatments. ADOPT provides a framework for how obesity researchers can collectively generate this evidence base and is a first step in an ongoing process that can be refined as the science advances. © 2018 The Obesity Society.

  14. Radiation protection in medicine (542) comparison of different dosimetry systems for dose measurements in diagnostic radiology

    International Nuclear Information System (INIS)

    Milkovic, D.; Ranogajec-Komor, M.; Miljanic, S.; Knezevic, Z.; Krpan, K.

    2006-01-01

    The dose measurement on patients in X-ray diagnostic is not simple, because low doses with low and various energies have to be measured. The aim of this preliminary study was to compare high sensitivity thermoluminescent dosimeter (T.L.D.) (LiF:Mg,Cu,P) and radio-photoluminescent (R.P.L.) glass dosimeters for dose measurements in routine X-ray diagnostic of chest of children. The energy dependence of the dosimeters was investigated in Secondary Standard Dosimetry Laboratory (SSDL). The energy range was 33- 65 keV mean energy, the dosimeters were placed free in air and on the water phantom. The results were compared to calculated values of Hp(10). The next step was the irradiation in a routine X-ray diagnostic unit. Irradiations were performed by the Shimadzu X-ray unit. The selected irradiation conditions were the same as that most commonly used for baby examinations. Doses were measured with dosimeters placed free-in-air and also with the dosimeters placed on the water phantom and baby phantom. The results show that the R.P.L. glass dosimeters and LiF:Mg,Cu,P based T.L.D. are suitable for low dose measurements in X-ray diagnostic. The uncertainty of dose determination is mainly caused by the energy dependence of dosimeters. (authors)

  15. Effective dose measurement at workplaces within an instrumented anthropomorphic phantom

    International Nuclear Information System (INIS)

    Villagrasa, C.; Darreon, J.; Martin-Burtat, N.; Clairand, I.; Colin, J.; Fontbonne, J. M.

    2011-01-01

    The Laboratory of Ionizing Radiation Dosimetry of the IRSN (France) is developing an instrumented anthropomorphic phantom in order to measure the effective dose for photon fields at workplaces. This anthropomorphic phantom will be equipped with small active detectors located inside at chosen positions. The aim of this paper is to present the development of these new detectors showing the results of the characterisation of the prototype under metrological conditions. New evaluations of the effective dose for standard and non-homogenous irradiation configurations taking into account the real constraints of the project have been done validating the feasibility and utility of the instrument. (authors)

  16. Measurement of radiation dose to the eye-lens with bilateral whole brain irradiation

    International Nuclear Information System (INIS)

    Kim, Ki Hwan; Park, Charn Il; Kang, Wee Saing; Choo, Dong Woon

    1985-01-01

    In 40 patients with metastatic brain tumor and acute lymphoblastic leukemia received whole brain irradiation, the dose delivered to the eye lens was measured using T.L.D. chips applied on the eyes as usual shield. The dose to the eye lens was expressed the relative dose to the mid brain dose. Radiotherapy was administrated using Co-60 teletherapy with bilateral whole brain irradiation. The results are as follows: 1. The dose to the right eye from its incipient field is 16.6% of tumor dose while the dose to the same eye from the opposite field is 41.2%. On left eye, 19.2% from incipient field while 39.2% from the opposite field. 2. Total received dose to right and left eyes is 28.9%, 29.8% of tumor dose respectively. 3. Comparing lens shield group with orbit shield group dose is 22.5%, 15.8% of tumor dose, respectively. 4. The dose delivered to the eye lens in ipsilateral side depends upon internal scattering, location of lead shield and penetrating dose of lead in itself. The dose in contralateral side depends upon divergency of radiation beam and patient's malposition. 5. The dose to the eye lens should be less than 10% of tumor dose with adequate shield, also not missing the chance of leptomeningeal recurrence because of overshielding.

  17. Dose delivered from Varian's CBCT to patients receiving IMRT for prostate cancer

    International Nuclear Information System (INIS)

    Wen Ning; Guan Huaiqun; Hammoud, Rabih; Pradhan, Deepak; Nurushev, T; Li Shidong; Movsas, Benjamin

    2007-01-01

    With the increased use of cone beam CT (CBCT) for daily patient setup, the accumulated dose from CBCT may be significantly higher than that from simulation CT or portal imaging. The objective of this work is to measure the dose from daily pelvic scans with fixed technical settings and collimations. CBCT scans were acquired in half-fan mode using a half bowtie and x-rays were delivered in pulsed-fluoro mode. The skin doses for seven prostate patients were measured on an IRB-approved protocol. TLD capsules were placed on the patient's skin at the central axis of three beams: AP, left lateral (Lt Lat) and right lateral (Rt Lat). To avoid the ring artefacts centred in the prostate, the treatment couch was dropped 3 cm from the patient's tattoo (central axis). The measured AP skin doses ranged 3-6 cGy for 20-33 cm separation. The larger the patient size the less the AP skin dose. Lateral doses did not change much with patient size. The Lt Lat dose was ∼4.0 cGy, which was ∼40% higher than the Rt Lat dose of ∼2.6 cGy. To verify this dose asymmetry, surface doses on an IMRT QA phantom (oval shaped, 30 cm x 20 cm) were measured at the same three sites using TLD capsules with 3 cm table-drop. The dose asymmetry was due to: (1) kV source rotation which always starts from the patient's Lt Lat and ends at Lt Lat. Gantry rotation gets much slower near the end of rotation but dose rate stays constant and (2) 370 0 scan rotation (10 0 scan overlap on the Lt Lat side). In vivo doses were measured inside a Rando pelvic heterogeneous phantom using TLDs. The left hip (femoral head and neck) received the highest doses of ∼10-11 cGy while the right hip received ∼6-7 cGy. The surface and in vivo doses were also measured for phantoms at the central-axis setup. The difference was less than ∼12% to the table-drop setup

  18. Measurement of Dose Received By Patients from Scattered Radiation in Diagnostic Radiology in Khartoum

    International Nuclear Information System (INIS)

    Ahmed, A.A.; Shaddad, I.A.

    2003-01-01

    Study on the measurement of the Entrance Surface Dose to patients (ESD) was conducted in 12 X-ray departments in different hospitals within Khartoum State. The number of adult patients covered was 117. Measurements were carried out in a situation where the diaphragm was opened at maximum field size (absence of light beam in the collimators), and another set when the diaphragm was opened at normal field size (i.e when the light beam is on). The measurements of doses in the case of chest (PA) exposure where collected from skull, cervical spine and lumbar spine (both males and females) and gonads for females only. In case of Abdomen (AP) exposure, the organs were chest, thyroid (both males and females) and gonads for males. TLD (LiF) were used for monitoring the radiation dose. The results indicate wide variations between both situations. It was found that the mean difference of doses in the absence of field collimation are greatest by 10 times for radiation dose reaching the chest (male and female),17 times in gonads (females) for abdomen exposure. Hence, it can be deduce that an increase of field size result in the increase of radiation dose delivered to other organs in the body like gonads and bone marrow for (males and females) that contain sensitive tissues

  19. Development of a fibre-optic dosemeter to measure the skin dose and percentage depth dose in the build-up region of therapeutic photon beams

    International Nuclear Information System (INIS)

    Kim, K. A.; Yoo, W. J.; Jang, K. W.; Moon, J.; Han, K. T.; Jeon, D.; Park, J. Y.; Cha, E. J.; Lee, B.

    2013-01-01

    In this study, a fibre-optic dosemeter (FOD) using an organic scintillator with a diameter of 0.5 mm for photon-beam therapy dosimetry was fabricated. The fabricated dosemeter has many advantages, including water equivalence, high spatial resolution, remote sensing and real-time measurement. The scintillating light generated from an organic-dosemeter probe embedded in a solid-water stack phantom is guided to a photomultiplier tube and an electrometer via 20 m of plastic optical fibre. Using this FOD, the skin dose and the percentage depth dose in the build-up region according to the depths of a solid-water stack phantom are measured with 6- and 15-MV photon-beam energies with field sizes of 10310 and 20320 cm 2 , respectively. The results are compared with those measured using conventional dosimetry films. It is expected that the proposed FOD can be effectively used in radiotherapy dosimetry for accurate measurement of the skin dose and the depth dose distribution in the build-up region due to its high spatial resolution. (authors)

  20. Effects of prolonged irradiation by low dose-rate ionizing radiation on the production of growth factors in murine bone marrow cells

    Energy Technology Data Exchange (ETDEWEB)

    Saitou, Mikio; Sirata, Katsutoshi; Yanai, Takanori; Tanaka, Satoshi; Onodera, Junichi; Otsu, Hiroshi; Sato, Fumiaki [Institute for Environmental Sciences, Department of Radiobiology, Rokkasho, Aomori (Japan)

    1999-07-01

    To evaluate effects of prolonged irradiation by low dose-rate ionizing radiation on the production of growth factors of cells, the dose dependency of the expression of cytokines, interleukin-6 (IL-6) and granulocyte-macrophage colony stimulating factor (GM-CSF), of mice is being measured at accumulated doses between 1 and 8 Gy, with the dose interval of 1 Gy. In the present work, specific-pathogen-free (SPF) C3H-HeN female mice were irradiated by {sup 137}Cs {gamma}-rays with the doses of 5-8 Gy at the dose rate of 20 mGy (22 h-day){sup -1}, and the expression of IL-6 and GM-CSF in bone marrow and spleen cells from the mice were measured semiquantitatively by the reverse transcriptase-polymerase chain reaction (RT-PCR) method. (author)