Stemcell Information: SKIP000326 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available 0.1007/s00401-013-1149-y Modeling key pathological features of frontotemporal dementia... SKIP000326 ... Diseased Carrier2 #1 Carrier2 #1 ... 前頭側頭型認知症 G310 FrontoTemporal D

Stemcell Information: SKIP000593 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000593 ... Diseased PDB3F-9 PDB3F-9 ... パーキンソン病 G20 Parkinson disease 168600 ... ... ... 19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patient-derived induc

Stemcell Information: SKIP000598 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000598 ... Diseased PDB4F-4 PDB4F-4 ... パーキンソン病 G20 Parkinson disease 168600 ... ...head Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patie

Stemcell Information: SKIP000604 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000604 ... Diseased PDD4F-1 PDD4F-1 ... パーキンソン病 G20 Parkinson disease 168600 ... ...head Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patie

Stemcell Information: SKIP000605 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000605 ... Diseased PDD4F-4 PDD4F-4 ... パーキンソン病 G20 Parkinson disease 168600 ... ...head Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patie

Stemcell Information: SKIP000608 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000608 ... Diseased PDD4F-9 PDD4F-9 ... パーキンソン病 G20 Parkinson disease 168600 ... ...head Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patie

Stemcell Information: SKIP000606 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000606 ... Diseased PDD4F-5 PDD4F-5 ... パーキンソン病 G20 Parkinson disease 168600 ... ...head Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patie

Stemcell Information: SKIP000595 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000595 ... Diseased PDB4F-1 PDB4F-1 ... パーキンソン病 G20 Parkinson disease 168600 ... ...head Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patie

Stemcell Information: SKIP000599 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000599 ... Diseased PDB4F-5 PDB4F-5 ... パーキンソン病 G20 Parkinson disease 168600 ... ...head Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patie

Stemcell Information: SKIP000597 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000597 ... Diseased PDB4F-3 PDB4F-3 ... パーキンソン病 G20 Parkinson disease 168600 ... ...head Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patie

Stemcell Information: SKIP000607 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000607 ... Diseased PDD4F-8 PDD4F-8 ... パーキンソン病 G20 Parkinson disease 168600 ... ...head Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patie

Stemcell Information: SKIP000592 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000592 ... Diseased PDB3F-8 PDB3F-8 ... パーキンソン病 G20 Parkinson disease 168600 ... ...ute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patient-derived

Stemcell Information: SKIP000296 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000296 ... Normal C2 C2 ... -- Female ... -- No Healthy control lin...e for L2-1,2,3Mut. Born in 1931 Healthy control line for L2-1,2,3Mut. Born in　1931 -- -- -- ... -- ... Yes I

Stemcell Information: SKIP000325 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available School ... 23836290 10.1007/s00401-013-1149-y Modeling key pathological features of frontotemporal dementia... SKIP000325 ... Diseased Carrier1 #6 Carrier1 #6 ... 前頭側頭型認知症 G310 FrontoTemporal D

Stemcell Information: SKIP000327 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available cal School ... 23836290 10.1007/s00401-013-1149-y Modeling key pathological features of frontotemporal dementia... SKIP000327 ... Diseased Carrier2 #11 Carrier2 #11 ... 前頭側頭型認知症 G310 FrontoTemporal

Stemcell Information: SKIP000324 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available School ... 23836290 10.1007/s00401-013-1149-y Modeling key pathological features of frontotemporal dementia... SKIP000324 ... Diseased Carrier1 #5 Carrier1 #5 ... 前頭側頭型認知症 G310 FrontoTemporal D

Stemcell Information: SKIP000610 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000610 ... Diseased PDE3F-4 PDE3F-4 ... パーキンソン病 G20 Parkinson disease 168600 ... ...69371 10.1016/j.cell.2009.02.013 Parkinson's disease patient-derived induced plur

Stemcell Information: SKIP000603 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000603 ... Diseased PDD3F-7 PDD3F-7 ... パーキンソン病 G20 Parkinson disease 168600 ... ...19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patient-derived induced p

Stemcell Information: SKIP000590 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000590 ... Diseased PDB3F-1 PDB3F-1 ... パーキンソン病 G20 Parkinson disease 168600 ... ...e ... 19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patient-derived in

Stemcell Information: SKIP000601 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000601 ... Diseased PDD3F-1 PDD3F-1 ... パーキンソン病 G20 Parkinson disease 168600 ... ...19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patient-derived induced p

Stemcell Information: SKIP000602 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000602 ... Diseased PDD3F-4 PDD3F-4 ... パーキンソン病 G20 Parkinson disease 168600 ... ...19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patient-derived induced p

Stemcell Information: SKIP000609 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000609 ... Diseased PDE3F-3 PDE3F-3 ... パーキンソン病 G20 Parkinson disease 168600 ... ...69371 10.1016/j.cell.2009.02.013 Parkinson's disease patient-derived induced plur

Stemcell Information: SKIP000241 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000241 ... Diseased HPS0183 HPS0183 ... 封入体筋炎 G724 Inclusion body myositis 147...421 ... -- -- ... Yes No intractable disease-specific iPSC derived from Inclution body myositis. 封入体筋炎患者由

Stemcell Information: SKIP000243 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000243 ... Diseased HPS0174 HPS0174 ... 皮膚筋炎 M339 Dermatopolymyositis 613825 ... ... ... -- -- ... Yes No intractable disease-specific iPSC derived from Dermatomyositis (DM). 皮膚筋炎患者由来iPS細胞株。|

Stemcell Information: SKIP000600 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000600 ... Diseased PDC3F-1 PDC3F-1 ... パーキンソン病 G20 Parkinson disease 168600 ... ...titute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patient-derived

Stemcell Information: SKIP000292 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available stem.2013.01.008 Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration ... SKIP000292 ... Diseased L1-2Mut L1-2Mut ... パーキンソン病 G20 Parkinson's disease 607060

Stemcell Information: SKIP000297 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available j.stem.2013.01.008 Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneratio... SKIP000297 ... Diseased L2-1Mut L2-1Mut ... パーキンソン病 G20 Parkinson's disease 607060

Stemcell Information: SKIP001117 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001117 ... Diseased D3-1 D3-1 ... 大うつ病 F33.3 major depression 605210 ... ...-- Male ... Yes No iPS cells derived from fibroblasts of a patient in which a frameshift mutation of disrupted in major depression

Stemcell Information: SKIP001118 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001118 ... Diseased D3-2 D3-2 ... 大うつ病 F33.3 major depression 605210 ... ...-- Male ... Yes No iPS cells derived from fibroblasts of a patient in which a frameshift mutation of disrupted in major depression

Stemcell Information: SKIP000594 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000594 ... Diseased PDB3F-d12 PDB3F-d12 ... パーキンソン病 G20 Parkinson disease 1686...he Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson's disease patient-derived induced

Stemcell Information: SKIP000763 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000763 ... Diseased PDB2lox-17 PDB2lox-17 ... パーキンソン病 G20 Parkinson disease 16...9371 10.1016/j.cell.2009.02.013 Parkinson's disease patient-derived induced pluripotent stem cells free of v

Stemcell Information: SKIP000765 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000765 ... Diseased PDB2lox-22 PDB2lox-22 ... パーキンソン病 G20 Parkinson disease 16...9371 10.1016/j.cell.2009.02.013 Parkinson's disease patient-derived induced pluripotent stem cells free of v

Stemcell Information: SKIP000542 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000542 ... Diseased PDA3F-1 PDA3F-1 ... パーキンソン病 G20 Parkinson disease 168600 ... ...udolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000953 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000953 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP06.1 SP06.1 ... パーキンソン病 G20 Parkinson...om human iPS-based models of genetic and sporadic Parkinson's disease. Sanchez-Da

Stemcell Information: SKIP000591 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000591 ... Diseased PDB3F-5 PDB3F-5 ... パーキンソン病 G20 Parkinson disease 168600 ... ...dolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000762 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000762 ... Diseased PDB2lox-5 PDB2lox-5 ... パーキンソン病 G20 Parkinson disease 1686...71 10.1016/j.cell.2009.02.013 Parkinson's disease patient-derived induced pluripotent stem cells free of vir

Stemcell Information: SKIP000856 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000856 ... Diseased HPS0256 HPS0256 ... アルツハイマー病 G309 Alzheimer disease 104300... ... -- -- ... No No Disease specific iPS cell line derived from a patient with Alzheimer disease アルツハイマー

Stemcell Information: SKIP000764 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000764 ... Diseased PDB2lox-21 PDB2lox-21 ... パーキンソン病 G20 Parkinson disease 16...9371 10.1016/j.cell.2009.02.013 Parkinson's disease patient-derived induced pluripotent stem cells free of v

Stemcell Information: SKIP001159 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... 0-9 Male ... -- No Human iPS cell lines derived from BJ human foreskin fibroblasts. 新生児包皮から得た線維芽細胞由来のヒトiPS細胞... SKIP001159 ... BJ Human Foreskin Fibroblasts 新生児包皮由来の線維芽細胞 Unknown 246G6 246G6 ... ... Shinya 山中 伸弥 Center for iPS Cell Research and Application (CiRA), Kyoto University 京都大学iPS細胞研究所 Center for ...iPS Cell Research and Application (CiRA), Kyoto University 京都大学iPS細胞研究所 Yamanaka Shinya 山中 伸弥 Information On...ly ... 18035408--22146343 10.1016/j.cell.2007.11.019--10.1038/mt.2011.266 Indu

Stemcell Information: SKIP001156 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... 0-9 Male ... -- No Human iPS cell lines derived from BJ human foreskin fibroblasts. 新生児包皮から得た線維芽細胞由来のヒトiPS細胞... SKIP001156 ... BJ Human Foreskin Fibroblasts 新生児包皮由来の線維芽細胞 Unknown 246G3 246G3 ... ...amanaka Shinya 山中 伸弥 Center for iPS Cell Research and Application (CiRA), Kyoto University 京都大学iPS細胞研究所 Cent...er for iPS Cell Research and Application (CiRA), Kyoto University 京都大学iPS細胞研究所 Yamanaka Shinya 山中 伸弥 Informa...tion Only ... 18035408--22146343 10.1016/j.cell.2007.11.019--10.1038/mt.2011.2

Stemcell Information: SKIP000823 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available line, derived from fibloblast(JCRB TIG114). TIG114線維芽細胞由来iPS細胞。エピゾーマルベクターによる樹立、導入細胞には...suke Okita 沖田　圭介 Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 Center for iPS ...Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 Shinya Yamanaka 山中伸弥... Information Only Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 http://www.cir... SKIP000823 ... Normal 418C-1 418C-1 ... 36 30-39 Male Japanese Japanese -- No Human iPS cell

Stemcell Information: SKIP000824 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available line, derived from fibloblast(JCRB TIG107). TIG107線維芽細胞由来iPS細胞。エピゾーマルベクターによる樹立、導入細胞...and ... No ... Keisuke Okita 沖田　圭介 Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ...Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 Shiny...a Yamanaka 山中伸弥 Information Only Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所... SKIP000824 ... Normal 421C-1 421C-1 ... 81 80-89 Female Japanese Japanese -- No Human iPS cell

Stemcell Information: SKIP000821 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available line, derived from fibloblast(Cell applications Inc. Lot1388). Lot1388線維芽細胞由来iPS細胞。エピゾーマルベクターによる樹立、導入細胞...No ... No ... Keisuke Okita 沖田　圭介 Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ...Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 Shiny...a Yamanaka 山中伸弥 Information Only Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所... SKIP000821 ... Normal 404C-2 404C-2 ... 36 30-39 Female ... -- No Human iPS cell

Stemcell Information: SKIP000300 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... 23472874 10.1016/j.stem.2013.01.008 Genetic correction of a LRRK2 mutation in human iPSCs links parkinson... SKIP000300 ... Diseased L2-1GC L2-1GC ... パーキンソン病 G20 Parkinson's disease 607060 ...

Stemcell Information: SKIP000290 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available 1016/j.stem.2013.01.008 Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegene... SKIP000290 ... Diseased L1-1Mut L1-1Mut ... パーキンソン病 G20 Parkinson's disease 607060

Stemcell Information: SKIP000299 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... 23472874 10.1016/j.stem.2013.01.008 Genetic correction of a LRRK2 mutation in human iPSCs links parkinsoni... SKIP000299 ... Diseased L2-3Mut L2-3Mut ... パーキンソン病 G20 Parkinson's disease 607060

Stemcell Information: SKIP000298 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... 23472874 10.1016/j.stem.2013.01.008 Genetic correction of a LRRK2 mutation in human iPSCs links parkinsoni... SKIP000298 ... Diseased L2-2Mut L2-2Mut ... パーキンソン病 G20 Parkinson's disease 607060

Stemcell Information: SKIP000235 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000235 ... Diseased HPS0270 HPS0270 ... アトピー性皮膚炎 L209 Atopic dermatitis 603165... ... -- -- ... Yes No iPS cell line derived from Atopic dermatitis patient. Same patient as HPS0271| アトピー性皮膚炎

Stemcell Information: SKIP000236 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000236 ... Diseased HPS0271 HPS0271 ... アトピー性皮膚炎 L210 Atopic dermatitis 603166... ... -- -- ... Yes No iPS cell line derived from Atopic dermatitis patient. Same patient as HPS0270| アトピー性皮膚炎

Stemcell Information: SKIP000968 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000968 ... Diseased PDB1lox-21Puro-12 PDB1lox-21Puro-12 ... パーキンソン病 G20 Parkinson...ch Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000974 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000974 ... Diseased PDB1lox-21GFP-41 PDB1lox-21GFP-41 ... パーキンソン病 G20 Parkinson...Jaenisch Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000948 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000948 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP14.2 SP14.2 ... パーキンソン病 G20 Parkinson...ic phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson

Stemcell Information: SKIP000943 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000943 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP08.2 SP08.2 ... パーキンソン病 G20 Parkinson...ific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson

Stemcell Information: SKIP000957 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000957 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP13.2 SP13.2 ... パーキンソン病 G20 Parkinson...cific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson

Stemcell Information: SKIP000960 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000960 ... Diseased PDB1lox-17GFP-55 PDB1lox-17GFP-55 ... パーキンソン病 G20 Parkinson...Jaenisch Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000973 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000973 ... Diseased PDB1lox-21Puro-28 PDB1lox-21Puro-28 ... パーキンソン病 G20 Parkinson...ch Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000951 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000951 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP05.1 SP05.1 ... パーキンソン病 G20 Parkinson... of genetic and sporadic Parkinson's disease. Sanchez-Danes A, Richaud-Patin Y, Carballo-Carbajal I, Jimenez

Stemcell Information: SKIP000969 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000969 ... Diseased PDB1lox-21Puro-13 PDB1lox-21Puro-13 ... パーキンソン病 G20 Parkinson...ch Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000962 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000962 ... Diseased PDB1lox-17Puro-10 PDB1lox-17Puro-10 ... パーキンソン病 G20 Parkinson...ch Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000971 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000971 ... Diseased PDB1lox-21Puro-20 PDB1lox-21Puro-20 ... パーキンソン病 G20 Parkinson...ch Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000967 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000967 ... Diseased PDB1lox-21Puro-5 PDB1lox-21Puro-5 ... パーキンソン病 G20 Parkinson... Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000966 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000966 ... Diseased PDB1lox-21GFP-19 PDB1lox-21GFP-19 ... パーキンソン病 G20 Parkinson...Jaenisch Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000937 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000937 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP01.4 SP01.4 ... パーキンソン病 G20 Parkinson...ific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson

Stemcell Information: SKIP000956 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000956 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP12.4 SP12.4 ... パーキンソン病 G20 Parkinson...cific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson

Stemcell Information: SKIP000954 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000954 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP06.2 SP06.2 ... パーキンソン病 G20 Parkinson... of genetic and sporadic Parkinson's disease. Sanchez-Danes A, Richaud-Patin Y, Carballo-Carbajal I, Jimenez

Stemcell Information: SKIP000952 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000952 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP05.2 SP05.2 ... パーキンソン病 G20 Parkinson...fic phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson

Stemcell Information: SKIP000950 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000950 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP16.3 SP16.3 ... パーキンソン病 G20 Parkinson...ific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson

Stemcell Information: SKIP000959 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000959 ... Diseased PDB1lox-17GFP-29 PDB1lox-17GFP-29 ... パーキンソン病 G20 Parkinson...Jaenisch Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000972 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000972 ... Diseased PDB1lox-21Puro-26 PDB1lox-21Puro-26 ... パーキンソン病 G20 Parkinson...ch Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000970 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000970 ... Diseased PDB1lox-21Puro-18 PDB1lox-21Puro-18 ... パーキンソン病 G20 Parkinson...ch Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000964 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000964 ... Diseased PDB1lox-17Puro-31 PDB1lox-17Puro-31 ... パーキンソン病 G20 Parkinson...ch Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000963 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000963 ... Diseased PDB1lox-17Puro-12 PDB1lox-17Puro-12 ... パーキンソン病 G20 Parkinson...ch Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000855 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000855 ... Diseased HPS0255 HPS0255 ... アルツハイマー病 G309 Alzheimer disease 104300... ... -- -- Japanese Japanese No No Disease specific iPS cell line derived from a patient with Alzheimer disease アルツハイマー

Stemcell Information: SKIP000854 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000854 ... Diseased HPS0254 HPS0254 ... アルツハイマー病 G309 Alzheimer disease 104300... ... -- -- Japanese Japanese No No Disease specific iPS cell line derived from a patient with Alzheimer disease アルツハイマー

Stemcell Information: SKIP000939 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000939 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP02.2 SP02.2 ... パーキンソン病 G20 Parkinson...ic phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson

Stemcell Information: SKIP000961 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000961 ... Diseased PDB1lox-17Puro-5 PDB1lox-17Puro-5 ... パーキンソン病 G20 Parkinson... Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000965 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000965 ... Diseased PDB1lox-17Puro-33 PDB1lox-17Puro-33 ... パーキンソン病 G20 Parkinson...ch Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkinson

Stemcell Information: SKIP000293 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... 23472874 10.1016/j.stem.2013.01.008 Genetic correction of a LRRK2 mutation in human iPSCs links parkinson... SKIP000293 ... Diseased L1-1GC2 L1-1GC2 ... パーキンソン病 G20 Parkinson's disease 607060

Stemcell Information: SKIP000253 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available 21490598 10.1038/nature09915 Modelling schizophrenia using human induced pluripo... SKIP000253 ... Diseased GM23760 GM23760 ... 統合失調症 F20 Schizophrenia 181500 ... ...(SCZD) .episodes of agitatation, delusions of persecutation, fear of assassination, father also affected. 統合失調症

Stemcell Information: SKIP000245 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000245 ... Diseased HPS0164 HPS0164 ... デュシェンヌ型筋ジストロフィー G710 Duchenne Muscular... Dystrophy 310200 ... -- -- ... Yes No intractable disease-specific iPSC derived from Duchenne Muscular Dystrophy. デュシェンヌ

Stemcell Information: SKIP000955 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000955 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP12.3 SP12.3 ... パーキンソン病 G20 Parkinson...ls of genetic and sporadic Parkinson's disease. Sanchez-Danes A, Richaud-Patin Y, Carballo-Carbajal I, Jimen

Stemcell Information: SKIP000945 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000945 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP10.1 SP10.1 ... パーキンソン病 G20 Parkinson...e neurons from human iPS-based models of genetic and sporadic Parkinson's disease. Sanchez-Danes A, Richaud-

Stemcell Information: SKIP000946 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000946 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP10.2 SP10.2 ... パーキンソン病 G20 Parkinson...sease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinso

Stemcell Information: SKIP000958 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000958 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP13.4 SP13.4 ... パーキンソン病 G20 Parkinson...ls of genetic and sporadic Parkinson's disease. Sanchez-Danes A, Richaud-Patin Y, Carballo-Carbajal I, Jimen

Stemcell Information: SKIP000936 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000936 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP01.1 SP01.1 ... パーキンソン病 G20 Parkinson...s of genetic and sporadic Parkinson's disease. Sanchez-Danes A, Richaud-Patin Y, Carballo-Carbajal I, Jimene

Stemcell Information: SKIP000949 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000949 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP16.2 SP16.2 ... パーキンソン病 G20 Parkinson...s of genetic and sporadic Parkinson's disease. Sanchez-Danes A, Richaud-Patin Y, Carballo-Carbajal I, Jimene

Stemcell Information: SKIP000942 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000942 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP08.1 SP08.1 ... パーキンソン病 G20 Parkinson...s of genetic and sporadic Parkinson's disease. Sanchez-Danes A, Richaud-Patin Y, Carballo-Carbajal I, Jimene

Stemcell Information: SKIP001141 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001141 ... cardiac fibroblast 心臓線維芽細胞 Normal ATCC-CYS0105 ATCC-CYS0105 ... ...mary cardiac fibroblasts obtained from a healthy donor. ... 健常人の心臓線維芽細胞由来iPS細胞。 human ES-like Research Grade Se

Stemcell Information: SKIP000816 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000816 ... Diseased ACH-8858-6 ACH-8858-6 ... 軟骨無形成症 Q774 Achondroplasia 10080...0 ... 30 30-39 Female Japanese Japanese Yes No Achondroplasia(GM08858)-specific iPSC.GM08858 is from the mother of GM08859. 軟骨無形成

Stemcell Information: SKIP000265 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000265 ... Diseased HPS0264 HPS0264 ... パーキンソン病 G20 Parkinson disease ... ... ... 40-49 Male ... Yes No iPS cell line derived from Parkinson disease patient. パーキンソン病患者由来| human ES-like -- Re

Stemcell Information: SKIP000151 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000151 ... Blastocyst 胚盤胞 Unknown KhES-2 KhES-2 ... -- -- ... -- No Embryonic Stem cell 胚性幹細胞...京都大学再生医科学研究所 ... 16707099 10.1016/j.bbrc.2006.04.135 Efficient establishment of human embryonic stem cell l

Stemcell Information: SKIP000888 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000888 ... T cells T細胞 Normal 24HM 24HM ... 24 20-29 Male Japanese 日本人 -- No iPS cell...s from healthy human T cells ヒト健常人由来iPS細胞 human ES-like Research Grade Plasmid OCT4,SOX2,KL

Stemcell Information: SKIP000815 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000815 ... Diseased ACH-8857-1 ACH-8857-1 ... 軟骨無形成症 Q774 Achondroplasia 10080...0 ... 34 30-39 Male Japanese Japanese Yes No Achondroplasia(GM08857)-specific iPSC.GM08857 is from the father of GM08859. 軟骨無形成症

Stemcell Information: SKIP000733 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000733 ... Diseased GM24666 GM24666 sAD2 sAD2 アルツハイマー病 G309 ALZHEIMER DISEAS...E 104300 ... 83 80-89 Male ... Yes Yes ALZHEIMER DISEASE(Sporadic AD) hiPSC derived from fibroblast アルツハイマー

Stemcell Information: SKIP000242 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000242 ... Diseased HPS0178 HPS0178 ... 全身性強皮症 M340 Systemic Scleroderma 18175...), Systematic Sclerosis (SSc)| 全身性強皮症 ... 全身性硬化症　患者由来iPS細胞株。| human ES-like -- Sendai virus Sendai Virus Vector

Stemcell Information: SKIP000240 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000240 ... Diseased HPS0184 HPS0184 ... 全身性強皮症 M340 Systemic Scleroderma 18175...), Systematic Sclerosis (SSc)| 全身性強皮症、全身性硬化症　患者由来iPS細胞株。| human ES-like -- Sendai virus Sendai Virus Vector

Stemcell Information: SKIP000382 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000382 ... Diseased HPS0244 HPS0244 ... X連鎖αサラセミア·精神遅滞（ATR-X）症候群 D560 X-Linked alpha-Thalassemia...fic iPS cell line derived from a patient : X-Linked alpha-Thalassemia, Mental Retardation Syndrome (ATR-X sy

Stemcell Information: SKIP000596 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000596 ... Diseased PDB4F-2 PDB4F-2 ... パーキンソン病 G20 Parkinson disease 168600 ... ...f Jaenisch Rudolf Jaenisch Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkins...on's disease patient-derived induced pluripotent stem ce

Stemcell Information: SKIP000589 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000589 ... Diseased PDA3F-5 PDA3F-5 ... パーキンソン病 G20 Parkinson disease 168600 ... ...Available The Whitehead Institute The Whitehead Institute ... 19269371 10.1016/j.cell.2009.02.013 Parkins...on's disease patient-derived induced pluripotent stem cells free of viral reprogram

Stemcell Information: SKIP000771 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available e PARK6 600116 ... -- -- ... Yes No iPS cell line derived from a patient with Parkinson's disease, Familial type, PARK6. 家族性パーキンソン... SKIP000771 ... Diseased PKA13 PKA13 ... 家族性パーキンソン病 G20 familial parkinson's diseas

Stemcell Information: SKIP000770 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available PARK6 600116 ... -- -- ... Yes No iPS cell line derived from a patient with Parkinson's disease, Familial type, PARK6. 家族性パーキンソン... SKIP000770 ... Diseased PKA5 PKA5 ... 家族性パーキンソン病 G20 familial parkinson's disease

Stemcell Information: SKIP000175 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available le Black Black -- No Apparently healthy iPSCs from fetal lung fibroblast cell culture (GM06114) 健常胎児肺線維芽細胞(GM06114)由来iPS細胞... SKIP000175 ... Lung Fibroblast 肺線維芽細胞 Normal GM23392 GM23392 ... 0-9 Ma

Stemcell Information: SKIP000388 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000388 ... Diseased HPS0207 HPS0207 ... X連鎖アルファ-サラセミア・精神遅滞(ATR-X)症候群 ... Alpha-Thalassemia...l line derived from a patient :Alpha-Thalassemia/Mental Retardation Syndrome, X-Linked; ATRX. ... 疾患特異的iPS細胞株。X

Stemcell Information: SKIP001101 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001101 ... o induced chondrogenic (iChon) cells ダイレクトリプログラミングで作製した軟骨細胞 ... Normal ...man Dermal Fibroblasts(1439 KURABO). 新生児皮膚繊維芽細胞(1439 KURABO)をダイレクトリプログラミングにより軟骨細胞へと誘導（iChon細胞） Other Researc... Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Cell Research ...and Application,Kyoto University 京都大学iPS細胞研究所　CiRA https://www.cira.kyoto-u.ac.jp/e/index.html ... 25187577 ...WT-1-iChon WT-1-iChon ... 0-9 Male ... -- No Direct iInduction of Chondrogenic(iChon) cells from Hu

Stemcell Information: SKIP001102 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001102 ... induced chondrogenic (iChon) cells ダイレクトリプログラミングで作製した軟骨細胞 ... Normal WT...n Dermal Fibroblasts(789013 KURABO). 新生児皮膚繊維芽細胞(789013 KURABO)をダイレクトリプログラミングにより軟骨細胞へと誘導（iChon細胞） Other Resea...n, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Cell Researc...h and Application,Kyoto University 京都大学iPS細胞研究所　CiRA https://www.cira.kyoto-u.ac.jp/e/index.html ... 2518757...-2-iChon WT-2-iChon ... 0-9 Male ... -- No Direct iInduction of Chondrogenic(iChon) cells from Huma

Stemcell Information: SKIP001076 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001076 ... Fibroblast 線維芽細胞 Diseased ND35666 ND35666 ... 筋萎縮性側索硬化症 G122 amyotrop...mutation. Same subject as ND20522 (LCL) ALS 由来 (ND29509線維芽細胞)　SOD1 D91A変異 LCL (ND20522)有 human ES-like Resea

Stemcell Information: SKIP000182 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000182 ... Diseased GM23226 GM23226 ... 1型糖尿病 E10 diabetes (mellitus), juvenil...roblast. Multifactorial Defect 遺伝性若年発症I型糖尿病患者線維芽細胞（GM02416)由来iPS細胞 多因子の異常 human ES-like -- Retrovirus Oct4,

Stemcell Information: SKIP001077 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001077 ... Fibroblast 線維芽細胞 Diseased ND35668 ND35668 ... 筋萎縮性側索硬化症 G122 amyotrop...1 E49K mutation ALS 由来 (ND39026 線維芽細胞)　SOD1 E49K 変異 ... human ES-like Research Grade Retrovirus Oct4, Sox2, Klf

Stemcell Information: SKIP000941 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000941 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP04.2 SP04.2 ... パーキンソン病 G20 Parkinson...of genetic and sporadic Parkinson's disease. Sanchez-Danes A, Richaud-Patin Y, Carballo-Carbajal I, Jimenez-...0215 Disease-specific phenotypes in dopamine neurons from human iPS-based models

Stemcell Information: SKIP000938 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000938 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP02.1 SP02.1 ... パーキンソン病 G20 Parkinson...of genetic and sporadic Parkinson's disease. Sanchez-Danes A, Richaud-Patin Y, Carballo-Carbajal I, Jimenez-...0215 Disease-specific phenotypes in dopamine neurons from human iPS-based models

Stemcell Information: SKIP000947 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000947 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP14.1 SP14.1 ... パーキンソン病 G20 Parkinson...of genetic and sporadic Parkinson's disease. Sanchez-Danes A, Richaud-Patin Y, Carballo-Carbajal I, Jimenez-...0215 Disease-specific phenotypes in dopamine neurons from human iPS-based models

Stemcell Information: SKIP001078 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001078 ... Fibroblast 線維芽細胞 Diseased ND35669 ND35669 NDS00076 NDS00076 筋萎縮性側索硬...(SNP, no amino acid change) ... ALS 患者由来 (線維芽細胞)　FIG4 27C>T (SNP アミノ酸置換なし） ... human ES-like Research Grade Retrov

Stemcell Information: SKIP000920 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000920 ... fibroblast 線維芽細胞 Diseased SLE#100H SLE#100H ... 全身性紅斑性狼瘡 M32.9 System...ic lupus erythematosus 152700 ... -- -- ... No No iPS cell line iPS cell line human ES-like Research Grad...Medicine, Mayo Clinic ... 22142803 10.1186/scrt89 Successful disease-specific induced pluripotent stem cell

Stemcell Information: SKIP000282 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000282 ... Diseased HPS0272 HPS0272 ... アトピー性皮膚炎 L209 Atopic dermatitis 603165...atitis. HPS0270 and HPS0271 are derived from the same patient. 疾患特異的iPS細胞株。アトピー性皮膚炎患者由来。HPS0270、HPS0271と同一人由

Stemcell Information: SKIP000734 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000734 ... Diseased GM24675 GM24675 APPDp2 APPDp2 アルツハイマー病 G309 ALZHEIMER DI... hiPSC derived from fibroblast 家族性アルツハイマー病患者（APP遺伝子重複)維芽細胞由来iPS細胞 human ES-like Research Grade Retrovirus OC

Stemcell Information: SKIP000279 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000279 ... Diseased HPS0192 HPS0192 ... 杉花粉症 J301 Allergic rhinitis (Pollen allergy) 607154 食物アレルギー...cell line derived from a patient: Allergic rhinitis (Pollen allergy). ... 疾患特異的iPS細胞株。杉花粉症 (カニアレルギーも)患者由来。 huma

Stemcell Information: SKIP000261 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available Sample_Detail.aspx?Ref=GM23762&PgId=166 ... 21490598 10.1038/nature09915 Modelling schizophrenia using human... SKIP000261 ... Diseased GM23762 GM23762 ... 統合失調症 F20 Schizophrenia 181500 ... ...cally affected with Shizophrenia(SCZD) . 統合失調症患者線維芽細胞(GM02497)由来iPS細胞株。 | human ES-like -- Retrovirus Oct4,

Stemcell Information: SKIP000176 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available male Black Black -- No Apparently healthy iPSCs from APPARENTLY HEALTHY FETAL lung fibroblast cell culture (GM06112) 健常胎児肺線維芽細胞... SKIP000176 ... Lung Fibroblast 肺線維芽細胞 Normal GM23413 GM23413 ... 0-9 Fe...(GM06112)由来iPS細胞株 human ES-like -- Retrovirus Oct4, Sox2, Klf, c-Myc, retroviral vectors

Stemcell Information: SKIP000837 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... 50-59 Male ... Yes No TPB11(DNAVEC) is iPSC line reprogrammed from a Parkinson disease patient's T-cells, wh... SKIP000837 ... Diseased TPB11 (DNAVEC) TPB11 (DNAVEC) ... 家族性パーキンソン病 ... G20 ... ...ich deleated exon 6 and 7 in parkin gene.DNAVEC: SeV vectors, which were produced by DNAVEC Corp.(Cytotune). パーキンソン

Stemcell Information: SKIP000838 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... 50-59 Male ... Yes No TPB27(DNAVEC) is iPSC line reprogrammed from a Parkinson disease patient's T-cells, wh... SKIP000838 ... Diseased TPB27 (DNAVEC) TPB27 (DNAVEC) ... 家族性パーキンソン病 ... G20 ... ...ich deleated exon 6 and 7 in parkin gene.DNAVEC: SeV vectors, which were produced by DNAVEC Corp.(Cytotune). パーキンソン

Stemcell Information: SKIP000836 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available 50-59 Male ... Yes No TPB8(DNAVEC) is iPSC line reprogrammed from a Parkinson disease patient's T-cells, which... SKIP000836 ... Diseased TPB8 (DNAVEC) TPB8 (DNAVEC) ... 家族性パーキンソン病 ... G20 ... ... deleated exon 6 and 7 in parkin gene.DNAVEC: SeV vectors, which were produced by DNAVEC Corp.(Cytotune). パーキンソン

Stemcell Information: SKIP000835 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available 50-59 Male ... Yes No TPB4(DNAVEC) is iPSC line reprogrammed from a Parkinson disease patient's T-cells, which... SKIP000835 ... Diseased TPB4 (DNAVEC) TPB4 (DNAVEC) ... 家族性パーキンソン病 ... G20 ... ... deleated exon 6 and 7 in parkin gene.DNAVEC: SeV vectors, which were produced by DNAVEC Corp.(Cytotune). パーキンソン

Stemcell Information: SKIP001103 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001103 ... induced chondrogenic (iChon) cells ダイレクトリプログラミングで作製した軟骨細胞 ... Diseased ...s have elevated ER stress and undergo apoptosis. 軟骨無発症患者線維芽細胞(GM07892)をダイレクトリプログラミングにより軟骨細胞...へと誘導（iChon細胞）。|小胞体ストレスが生じ、過度のアポトーシスが引き起こされていた。 Other Research Grade Retrovirus c-MYC, KLF4... ... Minoru Okada 岡田　稔 Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所... ... Information Only Center for iPS Cell Research and Application,Kyoto University 京都大学iPS細胞研究所　CiRA https:

Stemcell Information: SKIP001115 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001115 ... Diseased D2-1 D2-1 ... 統合失調症 F209 schizophrenia ... 605210 ... 39 ...30-39 Female ... Yes No iPS cells derived from fibroblasts of a patient in which a frameshift mutation of disrupted in schizophrenia... 1 ( DISC1 ) 統合失調症患者由来iPS細胞 human ES-like Research Grade Plasmid OCT4,SOX2,KLF4,c-MYC,

Stemcell Information: SKIP001116 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001116 ... Diseased D2-2 D2-2 ... 統合失調症 F209 schizophrenia ... 605210 ... 39 ...30-39 Female ... Yes No iPS cells derived from fibroblasts of a patient in which a frameshift mutation of disrupted in schizophrenia... 1 ( DISC1 ) 統合失調症患者由来iPS細胞 human ES-like Research Grade Plasmid OCT4,SOX2,KLF4,c-MYC,

Stemcell Information: SKIP000260 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available x?Ref=GM23761&PgId=166 ... 21490598 10.1038/nature09915 Modelling schizophrenia using human induced pluripot... SKIP000260 ... Diseased GM23761 GM23761 ... 統合失調症 F20 Schizophrenia 181500 ... ...h Shizophrenia(SCZD) . | 統合失調症患者線維芽細胞(GM01835)由来iPS細胞株| human ES-like -- Lentivirus Oct4, Sox2, Klf4, c-Myc,

Stemcell Information: SKIP000330 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000330 ... mesenchymal stem cell 間葉系幹細胞 polydactylous human fingers 指 Normal Yub...ovation. 独立行政法人医薬基盤研究所ＪＣＲＢ細胞バンク http://cellbank.nibio.go.jp/~cellbank/cgi-bin/search_res_det.cgi?DB_NUM=1&ID=3377 ... ...621BMC Yub621BMC JCRB1113 JCRB1113 ... -- -- ... -- No JCRB1113 ... bone marrow-derived mesenchymal stem cell

Stemcell Information: SKIP000333 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000333 ... mesenchymal stem cell 間葉系幹細胞 polydactylous human fingers 指 Normal Yub...ター研究所 ... Not Available National Institute of Biomedical Innovation. 独立行政法人医薬基盤研究所ＪＣＲＢ細胞バンク http://cellbank.nibio.go.jp/~cell... 10F Yub 10F JCRB1116 JCRB1116 ... -- -- ... -- No JCRB1116 mesenchymal stem cell finite proliferatio

Stemcell Information: SKIP000924 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000924 ... dermal fibroblast 表皮繊維芽細胞 Diseased CPVT-iPS c5 CPVT-iPS c5 ... カテコラミン... line iPS細胞 human ES-like Research Grade Retrovirus SOX2, KLF4, OCT3/4 and c-MYC (pMX-based...誘発多形性心室頻拍 I47.2 Catecholaminergic polymorphic ventricular tachycardia type 1 604772 ... 46 40-49 Female ... Yes No iPS cell

Stemcell Information: SKIP000328 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000328 ... mesenchymal stem cell 間葉系幹細胞 polydactylous human fingers 指 Normal Yub... ... Not Available National Institute of Biomedical Innovation. 独立行政法人医薬基盤研究所ＪＣＲＢ細胞バンク http://cellbank.nibio.go.jp/~cellbank/cgi-bin/search_res_det.cgi?DB_NUM=1&ID=3375 ... ...621c Yub621c JCRB1111 JCRB1111 ... -- -- ... -- No JCRB1111 cartilige-derived messenchymal stem cell.

Stemcell Information: SKIP000748 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available B1345. Ph1 chromosome-positive human acute lymphoblastic leukemia cell line. Single Ph1 chromosome observed. 白血病... SKIP000748 ... acute lymphoblastic leukemia cell line 急性リンパ芽球 ... Diseased PALL-2 PALL...c and molecular analysis of Ph1-chromosome-positive acute lymphoblastic leukemia cell lines. Miyagi T, Ohyas...-2 JCRB1345 JCRB1345 急性リンパ性白血病 C910 Acute lymphoblastic leukaemia [ALL] 613065 ... -- Male ... Yes No JCR

Stemcell Information: SKIP000280 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000280 ... Diseased HPS0209 HPS0209 ... 肺性高血圧症 I270 Pulmonary hypertension 178...600 ... -- -- Japanese Japanese Yes No Disease specific iPS cell line derived from a patient: Pulmonary hypertension.... ... 疾患特異的iPS細胞株。肺性高血圧症患者由来。 human ES-like -- Sendai virus SeV18+HS-OCT3/4/TSΔF, SeV18+HS-SOX2/TS

Stemcell Information: SKIP000865 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000865 ... Diseased HPS0211 HPS0211 ... 肺性高血圧症 I270 Pulmonary hypertension 178...600 ... -- -- Japanese 日本人 Yes No Disease specific iPS cell line derived from a patient : Pulmonary hypertension.... HPS0209 was derived from the same patient. ... 疾患特異的iPS細胞株。肺性高血圧症患者由来。HPS0209と同一人由来。 human ES-like R

Stemcell Information: SKIP000329 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000329 ... mesenchymal stem cell 間葉系幹細胞 polydactylous human fingers 指 Normal Yub... Available National Institute of Biomedical Innovation. 独立行政法人医薬基盤研究所ＪＣＲＢ細胞バンク http://cellbank.nibio.go.jp/~cellbank/cgi-bin/search_res_det.cgi?DB_NUM=1&ID=3376 ... ...621b Yub621b JCRB1112 JCRB1112 ... -- -- ... -- No JCRB1112 bone-derived mesenchymal stem cell. finit

Stemcell Information: SKIP000817 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000817 ... Diseased ACHhomo-8859-3 ACHhomo-8859-3 ... 軟骨無形成症 Q774 Achondroplasia... 100800 ... 0-9 Female Japanese Japanese Yes No Achondroplasia(GM08859)-specific iPSC.GM08859 is from... the homozygous child of GM08857 and GM08858. 軟骨無形成症患者(GM08859)繊維芽細胞由来iPS細胞。|GM08859はGM08858の母親とGM08857の父親の子

Stemcell Information: SKIP000993 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ISEASE 8, AUTOSOMAL DOMINANT; PARK8 607060 ... 78 70-79 Female ... Yes No iPS cells from familial Parkinson... SKIP000993 ... Diseased PARK8-LB16 PARK8-LB16 ... 遺伝性パーキンソン病：PARK8 G20 PARKINSON D...'s disease patient ... 遺伝性パーキンソン病患者由来iPS細胞 human ES-like Research Grade Lentivirus Klf4, Sox2, Oct4, c-Myc ... Ye

Stemcell Information: SKIP000991 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available EASE 8, AUTOSOMAL DOMINANT; PARK8 607060 ... 66 60-69 Female ... Yes No iPS cells from familial Parkinson's disease patient ... 遺伝性パーキ... SKIP000991 ... Diseased PARK8-LA5 PARK8-LA5 ... 遺伝性パーキンソン病：PARK8 G20 PARKINSON DIS...ンソン病患者由来iPS細胞 human ES-like Research Grade Lentivirus Klf4, Sox2, Oct4, c-Myc ... Yes

Stemcell Information: SKIP000992 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ISEASE 8, AUTOSOMAL DOMINANT; PARK8 607060 ... 66 60-69 Female ... Yes No iPS cells from familial Parkinson... SKIP000992 ... Diseased PARK8-LA11 PARK8-LA11 ... 遺伝性パーキンソン病：PARK8 G20 PARKINSON D...'s disease patient ... 遺伝性パーキンソン病患者由来iPS細胞 human ES-like Research Grade Lentivirus Klf4, Sox2, Oct4, c-Myc ... Ye

Stemcell Information: SKIP000994 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ISEASE 8, AUTOSOMAL DOMINANT; PARK8 607060 ... 78 70-79 Female ... Yes No iPS cells from familial Parkinson... SKIP000994 ... Diseased PARK8-LB21 PARK8-LB21 ... 遺伝性パーキンソン病：PARK8 G20 PARKINSON D...'s disease patient ... 遺伝性パーキンソン病患者由来iPS細胞 human ES-like Research Grade Lentivirus Klf4, Sox2, Oct4, c-Myc ... Ye

Stemcell Information: SKIP000845 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000845 ... unknown 不明 Diseased Sporadic PD-1 Sporadic PD-1 10005.117.01 10005.117.01 パーキンソン病 G20 Parkin...son Disease 168600 ... 65 60-69 Female ... No No Transgene-free iPS cells from Sporadic Parkinson...lrep.2014.10.023 iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson... Disease patient.Using CytoTune iPS Sendai reprogramming protocol (Life Technologies). 孤発性パーキンソン

Stemcell Information: SKIP000944 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available inson disease 168006 ... 66 60-69 Female ... No No iPS cell line iPS細胞 human ES-like Research Grade Retrov... SKIP000944 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP08.3 SP08.3 ... パーキンソン病 G20 Park...irus SOX2, KLF4 and OCT3/4 Yes Yes MEFs Lines of patient-specific iPS cells were maintained by mechanical di...ssociation of colonies and splitting 1:3 onto feeder cells in hESC medium or by l

Stemcell Information: SKIP000644 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000644 ... umbilical cord 臍帯(線維芽細胞) Normal HiPS-RIKEN-2D HiPS-RIKEN-2D ... ...bilical cord fibroblast, male) 臍帯由来線維芽細胞（RCB0197 HUC-Fm)iPS細胞. human ES-like Research Grade Retrovirus ... Oct3... ... Fetus Male Japanese Japanese -- No Human iPS cell line. Parent cell line of RCB0197 HUC-Fm(Normal um...010.00091.x Establishment of induced pluripotent stem cells from human neonatal tissues. Fujioka T, Shimizu

Stemcell Information: SKIP000706 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000706 ... mesenchymal stem cell 間葉系幹細胞 placenta 胎盤 Normal PL502 PL502 ... ... ... -- -- ... -- No JCRB1125 mesenchymal stem cell. finite prolieferation 胎盤由来間葉系幹細胞(有限増殖) fibroblast-like -...lable National Institute of Biomedical Innovation. 独立行政法人医薬基盤研究所ＪＣＲＢ細胞バンク http://cellbank.nibio.go.jp/~cellbank/cgi-bin/search_res_det.cgi?DB_NUM=1&ID=3548 ...

Stemcell Information: SKIP000940 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available inson disease 168006 ... 46 40-49 Male ... No No iPS cell line iPS細胞 human ES-like Research Grade Retrovir... SKIP000940 ... dermal fibroblast 表皮繊維芽細胞 Diseased SP04.1 SP04.1 ... パーキンソン病 G20 Park...us SOX2, KLF4 and OCT3/4 Yes Yes MEFs Lines of patient-specific iPS cells were maintained by mechanical diss...ociation of colonies and splitting 1:3 onto feeder cells in hESC medium or by lim

Stemcell Information: SKIP000637 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000637 ... umbilical cord 臍帯(線維芽細胞) Normal HiPS-RIKEN-1B HiPS-RIKEN-1B ... ...umbilical cord fibroblast,Female) 臍帯由来線維芽細胞（RCB0436 HUC-F2)iPS細胞. human ES-like Research Grade Retrovirus Oc... ... Fetus Female Japanese Japanese -- No Human iPS cell line. Parent cell line of RCB0436 HUC-F2(Normal ...774.2010.00091.x Establishment of induced pluripotent stem cells from human neonatal tissues. Fujioka T, Shi

Stemcell Information: SKIP000639 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000639 ... umbilical cord 臍帯(線維芽細胞) Normal HiPS-RIKEN-1D HiPS-RIKEN-1D ... ... umbilical cord fibroblast,Female) 臍帯由来線維芽細胞（RCB0436 HUC-F2)iPS細胞. human ES-like Research Grade Retrovirus O... ... Fetus Female Japanese Japanese -- No Human iPS cell line. Parent cell line of ... RCB0436 HUC-F2(Normal...774.2010.00091.x Establishment of induced pluripotent stem cells from human neonatal tissues. Fujioka T, Shi

Stemcell Information: SKIP000648 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000648 ... umbilical cord 臍帯(線維芽細胞) Normal HiPS-RIKEN-13B HiPS-RIKEN-13B ... ... cord fibroblast, male) 臍帯由来線維芽細胞（HUC-5)iPS細胞. human ES-like Research Grade Retrovirus Oct3/4, Sox2, Klf4,c-... ... Fetus Male Japanese Japanese -- No Human iPS cell line. Parent cell line of HUC-5(Normal umbilical...blishment of induced pluripotent stem cells from human neonatal tissues. Fujioka T, Shimizu N, Yoshino K, Mi

Stemcell Information: SKIP000652 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available both neonatal and maternal cells. 羊膜(母胎・胎児）由来線維芽細胞（HFM-1)由来iPS細胞. human ES-like Research Grade Retrovirus Oc... SKIP000652 ... amnion 羊膜 Normal HiPS-RIKEN-3D HiPS-RIKEN-3D ... Fetus Male ... -- No Human iPS cel...l line. Parent cell line of HFM-1(amniotic membrane cells).HFM-1 were derived from ...2010.00091.x Establishment of induced pluripotent stem cells from human neonatal tissues. Fujioka T, Shimizu

Stemcell Information: SKIP000640 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000640 ... umbilical cord 臍帯(線維芽細胞) Normal HiPS-RIKEN-1E HiPS-RIKEN-1E ... ...umbilical cord fibroblast,Female) 臍帯由来線維芽細胞（RCB0436 HUC-F2)iPS細胞. human ES-like Research Grade Retrovirus Oc... ... Fetus Female Japanese Japanese -- No Human iPS cell line. Parent cell line of RCB0436 HUC-F2(Normal ...74.2010.00091.x Establishment of induced pluripotent stem cells from human neonatal tissues. Fujioka T, Shim

Stemcell Information: SKIP000655 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available both neonatal and maternal cells. 羊膜(母胎・胎児）由来線維芽細胞（HFM-1)由来iPS細胞. human ES-like Research Grade Lentivirus Oc... SKIP000655 ... amnion 羊膜 Normal HiPS-RIKEN-4B HiPS-RIKEN-4B ... Fetus Male ... -- No Human iPS cel...l line. Parent cell line of HFM-1(amniotic membrane cells).HFM-1 were derived from ...4.2010.00091.x Establishment of induced pluripotent stem cells from human neonatal tissues. Fujioka T, Shimi

Stemcell Information: SKIP000653 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available both neonatal and maternal cells. 羊膜(母胎・胎児）由来線維芽細胞（HFM-1)由来iPS細胞. human ES-like Research Grade Retrovirus Oc... SKIP000653 ... amnion 羊膜 Normal HiPS-RIKEN-3E HiPS-RIKEN-3E ... Fetus Male ... -- No Human iPS cel...l line. Parent cell line of HFM-1(amniotic membrane cells).HFM-1 were derived from ...2010.00091.x Establishment of induced pluripotent stem cells from human neonatal tissues. Fujioka T, Shimizu

Stemcell Information: SKIP000617 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000617 ... Diseased HPS0097 HPS0097 ... 家族性パーキンソン病 PARK2 G20 Parkinson's disea...se, Familial type, PARK2 600116 ... -- -- Japanese Japanese No No Disease specific iPS cell line derived from a patient: Parkins...on's disease, Familial type, PARK2. 疾患特異的iPS細胞株。家族性パーキンソン病 PARK2患者由来。レトロウイルスベクターにより

Stemcell Information: SKIP001068 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available DISEASE, PARK4 605543 ... 42 40-49 Male ... Yes No Disease specific iPS cell lines derived from patient with Parkinson...rsity Stanford University ... 22110584 10.1371/journal.pone.0026159 SNCA triplication Parkinson... SKIP001068 ... Diseased Trpl17 Trpl17 ... 家族性パーキンソン病 PARK4 G20 Familial PARKINSON ... disease (PARK4) パーキンソン病（PARK4）患者由来iPS細胞 human ES-like Research Grade Retrovirus KLF4,SOX2,OCT4,

Stemcell Information: SKIP000418 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available Princess ... Fetus Unknown ... -- No MRC-iPS-05|MRC5-derived iPS cells| MRC5由来iPS細胞| human ES-like R... SKIP000418 ... fetal lung fibroblast 胎児肺線維芽細胞 Unknown MRC-iPS-5 MRC-iPS-5 Princess...e.0013017 Lectin microarray analysis of pluripotent and multipotent stem cells.--DNA methylation dynamics in... human induced pluripotent stem cells over time.--Mesenchymal to embryonic incomp...lete transition of human cells by chimeric OCT4/3 (POU5F1) with physiological co-activator EWS.--Defining hy

Stemcell Information: SKIP000390 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available lections/NIGMS/ipsc_list.aspx?PgId=696 ... 21490598 10.1038/nature09915 Modelling schizophrenia using human ... SKIP000390 ... Diseased GM23764 GM23764 ... 統合失調症 F209 Schizophrenia 181500 ... ...より人工多能性幹細胞 (iPSC) を樹立。23回継代の凍結サンプル。同一人由来のリンパ球GM01490も参照。青年期から神経性無食欲症を発症。鬱＜統合失調症。

Stemcell Information: SKIP000474 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available Gideon ... Fetus Unknown ... -- No MRC-iPS-62|MRC5-derived iPS cells| MRC5由来iPS細胞| human ES-like Res... SKIP000474 ... fetal lung fibroblast 胎児肺線維芽細胞 Unknown MRC-iPS-62 MRC-iPS-62 Gideon...459.x--10.1371/journal.pgen.1002085 Lectin microarray analysis of pluripotent and multipotent stem cells.--D...NA methylation dynamics in human induced pluripotent stem cells over time. Toyoda M, Yamazaki-Inoue M, Itaku...med/21155951--http://www.ncbi.nlm.nih.gov/pubmed/21637780 -- Some of clones of the same original cells have been used in the papers.

Stemcell Information: SKIP000494 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available eyes Snake eyes ... Fetus Unknown ... -- No MRC-iPS-83|MRC5-derived iPS cells| MRC5由来iPS細胞| human ES-... SKIP000494 ... fetal lung fibroblast 胎児肺線維芽細胞 Unknown MRC-iPS-83 MRC-iPS-83 Snake ....2010.01459.x--10.1371/journal.pgen.1002085 Lectin microarray analysis of pluripotent and multipotent stem cell...s.--DNA methylation dynamics in human induced pluripotent stem cells over time. Toyoda M, Yamazaki-Inoue ....gov/pubmed/21155951--http://www.ncbi.nlm.nih.gov/pubmed/21637780 -- Some of clones of the same original cells have been used in the papers.

Stemcell Information: SKIP000498 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available y Diggity ... Fetus Unknown ... -- No MRC-iPS-86|MRC5-derived iPS cells| MRC5由来iPS細胞| human ES-like R... SKIP000498 ... fetal lung fibroblast 胎児肺線維芽細胞 Unknown MRC-iPS-86 MRC-iPS-86 Diggit...01459.x--10.1371/journal.pgen.1002085 Lectin microarray analysis of pluripotent and multipotent stem cells.-...-DNA methylation dynamics in human induced pluripotent stem cells over time. Toyoda M, Yamazaki-Inoue M, Ita...ubmed/21155951--http://www.ncbi.nlm.nih.gov/pubmed/21637780 -- Some of clones of the same original cells have been used in the papers.

Stemcell Information: SKIP000433 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available pper Gobstopper ... Fetus Unknown ... -- No MRC-iPS-21|MRC5-derived iPS cells| MRC5由来iPS細胞| human ES-... SKIP000433 ... fetal lung fibroblast 胎児肺線維芽細胞 Unknown MRC-iPS-21 MRC-iPS-21 Gobsto....2010.01459.x--10.1371/journal.pgen.1002085 Lectin microarray analysis of pluripotent and multipotent stem cell...s.--DNA methylation dynamics in human induced pluripotent stem cells over time. Toyoda M, Yamazaki-Inoue ....gov/pubmed/21155951--http://www.ncbi.nlm.nih.gov/pubmed/21637780 -- Some of clones of the same original cells have been used in the papers.

Stemcell Information: SKIP000478 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available g ... Fetus Unknown ... -- No MRC-iPS-66|MRC5-derived iPS cells| MRC5由来iPS細胞| human ES-like Research ... SKIP000478 ... fetal lung fibroblast 胎児肺線維芽細胞 Unknown MRC-iPS-66 MRC-iPS-66 Tug Tu...-10.1371/journal.pgen.1002085 Lectin microarray analysis of pluripotent and multipotent stem cells.--DNA met...hylation dynamics in human induced pluripotent stem cells over time. Toyoda M, Yamazaki-Inoue M, Itakura Y, ...155951--http://www.ncbi.nlm.nih.gov/pubmed/21637780 -- Some of clones of the same original cells have been used in the papers.

Stemcell Information: SKIP000457 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available s Jimmies ... Fetus Unknown ... -- No MRC-iPS-45|MRC5-derived iPS cells| MRC5由来iPS細胞| human ES-like R... SKIP000457 ... fetal lung fibroblast 胎児肺線維芽細胞 Unknown MRC-iPS-45 MRC-iPS-45 Jimmie...01459.x--10.1371/journal.pgen.1002085 Lectin microarray analysis of pluripotent and multipotent stem cells.-...-DNA methylation dynamics in human induced pluripotent stem cells over time. Toyoda M, Yamazaki-Inoue M, Ita...ubmed/21155951--http://www.ncbi.nlm.nih.gov/pubmed/21637780 -- Some of clones of the same original cells have been used in the papers.

Stemcell Information: SKIP000437 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available c ... Fetus Unknown ... -- No MRC-iPS-25|MRC5-derived iPS cells| MRC5由来iPS細胞| human ES-like Research ... SKIP000437 ... fetal lung fibroblast 胎児肺線維芽細胞 Unknown MRC-iPS-25 MRC-iPS-25 Tic Ti...-10.1371/journal.pgen.1002085 Lectin microarray analysis of pluripotent and multipotent stem cells.--DNA met...hylation dynamics in human induced pluripotent stem cells over time. Toyoda M, Yamazaki-Inoue M, Itakura Y, ...155951--http://www.ncbi.nlm.nih.gov/pubmed/21637780 -- Some of clones of the same original cells have been used in the papers.

Stemcell Information: SKIP000444 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available b ... Fetus Unknown ... -- No MRC-iPS-32|MRC5-derived iPS cells| MRC5由来iPS細胞| human ES-like Research ... SKIP000444 ... fetal lung fibroblast 胎児肺線維芽細胞 Unknown MRC-iPS-32 MRC-iPS-32 Bob Bo....pgen.1002085 Lectin microarray analysis of pluripotent and multipotent stem cells.--DNA methylation dynamic...s in human induced pluripotent stem cells over time. Toyoda M, Yamazaki-Inoue M, Itakura Y, Kuno A, Ogawa T,...ww.ncbi.nlm.nih.gov/pubmed/21637780 -- Some of clones of the same original cells have been used in the papers.

Stemcell Information: SKIP000708 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000708 ... mesenchymal stem cell 間葉系幹細胞 placenta 胎盤 Normal PL505 PL505 ... ... ... -- -- ... -- No JCRB1128 mesenchymal stem cell finite proliferation 胎盤由来間葉系幹細胞(有限増殖) fibroblast-like -- ...opment 国立成育医療研究センター研究所 ... Not Available National Institute of Biomedical Innovation. 独立行政法人医薬基盤研究所ＪＣＲＢ細胞...バンク http://cellbank.nibio.go.jp/~cellbank/cgi-bin/search_res_det.cgi?DB_NUM=1&ID=3558 ...

Stemcell Information: SKIP000707 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available 胎盤由来間葉系幹細胞 fibroblast-like -- -- ... -- ... When the cultures reached subconfluence, the cell...evelopment 国立成育医療研究センター研究所 ... Not Available National Institute of Biomedical Innovation. 独立行政法人医薬基盤研究所ＪＣＲＢ細胞バンク http://cell... SKIP000707 ... placenta 胎盤 Normal PL504 PL504 ... -- -- ... -- No JCRB1126 mesenchymal stem cell...s were harvested with 0.25% trypsin and 1mM EDTA and replated with one-quarter of harvested cells ... 5% ... ...bank.nibio.go.jp/~cellbank/cgi-bin/search_res_det.cgi?DB_NUM=1&ID=3549 ...

Stemcell Information: SKIP000287 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000287 ... mesenchymal stem cell 間葉系幹細胞 Umbilical cord blood 臍帯血 Normal UCB408E7...ot Available National Institute of Biomedical Innovation. 独立行政法人医薬基盤研究所ＪＣＲＢ細胞バンク http://cellbank.nibio.go.jp/~cell...s with transgenic HPV E7. finite proliferation 臍帯血由来間葉系幹細胞 (有限増殖) fibroblast-like -- Retr...-32 UCB408E7-32 JCRB1109 JCRB1109 ... -- -- ... -- No JCRB1109 ... Human umbilical cord blood-derived mesenchymal stem cell...bank/cgi-bin/search_res_det.cgi?DB_NUM=1&ID=3373 ... 15647378 ... Immortalization of human fetal cell

Stemcell Information: SKIP000414 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available bba ... Fetus Male ... -- No MRC-iPS-01|MRC5(a 14-week male foetal lung tissue)-derived iPS cells| MRC5(14週男性胎児胚線維芽細胞）由来iPS細胞... SKIP000414 ... fetal lung fibroblast 胎児肺線維芽細胞 Unknown MRC-iPS-1 MRC-iPS-1 Bubba Bu...10.1016/j.yexcr.2009.06.016--10.1371/journal.pone.0013017 Lectin microarray analysis of pluripotent and multipotent stem cell...s.--DNA methylation dynamics in human induced pluripotent stem cell...s over time.--Mesenchymal to embryonic incomplete transition of human cells by chimeric OCT4/3 (POU5F1) w

Stemcell Information: SKIP001144 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available l line derived from a healthy individual cord blood. ... 健常人の臍帯血由来のヒトiPS細胞株。 human ES-...for iPS Cell Research and Application (CiRA), Kyoto University 京都大学iPS細胞研究所 Center for iPS Cell Research and... Application (CiRA), Kyoto University 京都大学iPS細胞研究所 Yamanaka Shinya 山中 伸弥 Available RIKEN BioResource Center ... SKIP001144 ... cord blood 臍帯血 Normal HPS0331 HPS0331 610B1 610B1 ... -- Male ... -- No Human iPS cel...理化学研究所 バイオリソースセンター ... http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0331&

Stemcell Information: SKIP001190 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001190 ... blood mononuclear cell 血中単核細胞 Diseased HPS0414 HPS0414 ... 原発性側索硬化症 G...m a patient :Primary lateral sclerosis (PLS). ... 原発性側索硬化症由来iPS細胞株。 human ES-like Research Grade Other Oct3/4, ...122 Primary Lateral Sclerosis ... -- -- Japanese 日本人 Yes No Disease specific iPS cell line derived fro...EN BioResource Center 理化学研究所 バイオリソースセンター ... Available RIKEN BioResource Center 理化学研究所 バイオリソースセンター ... http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0414&type=1 ...

Stemcell Information: SKIP001192 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001192 ... blood mononuclear cell 血中単核細胞 Diseased HPS0429 HPS0429 CiRA00142 Ci...d from a patient :Charcot-Marie-Tooth disease . ... シャルコー·マリー·トゥース病患者由来iPS細胞株。 human ES-like Research Grade Pla...ll Research and Application (CiRA), Kyoto University 京都大学iPS細胞研究所 Center for iPS Cell Research and Applicati...on (CiRA), Kyoto University 京都大学iPS細胞研究所 Yamanaka Shinya 山中 伸弥 Available RIKEN Bi...RA00142 シャルコー・マリー・トゥース病 G600 Charcot-Marie-Tooth disease 118210 ... -- -- ... Yes No iPS cell line derive

Stemcell Information: SKIP001006 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available e AB. タカラバイオヨーロッパAB Takara Bio Europe AB. タカラバイオヨーロッパAB Takara Bio Europe AB. タカラバイオヨーロッパAB Takara Bio Europ...e AB. タカラバイオヨーロッパAB Available Takara Bio Europe AB. タカラバイオヨーロッパAB http://www.clonte... SKIP001006 ... Normal ChiPSC21 ChiPSC21 Y00315 Y00315 ... 26 20-29 Male Europe...ovirus Oct4,SOX2,KLF4,c-Myc ... -- ... Negative ... Yes ... Yes ... Yes G-banding Yes ... Yes ... Takara Bio Europ...an/North African European/North African -- No Cellartis human iPS cell line 21 (ChiPSC21)|Research Gra

Stemcell Information: SKIP001004 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available e AB. タカラバイオヨーロッパAB Takara Bio Europe AB. タカラバイオヨーロッパAB Takara Bio Europe AB. タカラバイオヨーロッパAB Takara Bio Europ...e AB. タカラバイオヨーロッパAB Available Takara Bio Europe AB. タカラバイオヨーロッパAB http://www.clonte... SKIP001004 ... Normal ChiPSC12 ChiPSC12 Y00285 Y00285 ... 24 20-29 Male Europe...ovirus Oct4,SOX2,KLF4,c-Myc ... -- ... Negative ... Yes ... Yes ... Yes G-banding Yes ... Yes ... Takara Bio Europ...an/North African European/North African -- No Cellartis human iPS cell line 12 (ChiPSC12)|Research Gra

Stemcell Information: SKIP001005 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available e AB. タカラバイオヨーロッパAB Takara Bio Europe AB. タカラバイオヨーロッパAB Takara Bio Europe AB. タカラバイオヨーロッパAB Takara Bio Europ...e AB. タカラバイオヨーロッパAB Available Takara Bio Europe AB. タカラバイオヨーロッパAB http://www.clonte... SKIP001005 ... Normal ChiPSC18 ChiPSC18 Y00305 Y00305 ... 32 30-39 Male Europe...ovirus Oct4,SOX2,KLF4,c-Myc ... -- ... Negative ... Yes ... Yes ... Yes G-banding Yes ... Yes ... Takara Bio Europ...an/North African European/North African -- No Cellartis human iPS cell line 18 (ChiPSC18)|Research Gra

Stemcell Information: SKIP001007 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available e AB. タカラバイオヨーロッパAB Takara Bio Europe AB. タカラバイオヨーロッパAB Takara Bio Europe AB. タカラバイオヨーロッパAB Takara Bio Europ...e AB. タカラバイオヨーロッパAB Available Takara Bio Europe AB. タカラバイオヨーロッパAB http://www.clonte... SKIP001007 ... Normal ChiPSC22 ChiPSC22 Y00325 Y00325 ... 32 30-39 Male Europe...ovirus Oct4,SOX2,KLF4,c-Myc ... -- ... Negative ... Yes ... Yes ... Yes G-banding Yes ... Yes ... Takara Bio Europ...an/North African European/North African -- No Cellartis human iPS cell line 22 (ChiPSC22)|Research Gra

Stemcell Information: SKIP001003 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available AB. タカラバイオヨーロッパAB Takara Bio Europe AB. タカラバイオヨーロッパAB Takara Bio Europe AB. タカラバイオヨーロッパAB Takara Bio Europe... AB. タカラバイオヨーロッパAB Available Takara Bio Europe AB. タカラバイオヨーロッパAB http://www.clontech.c... SKIP001003 ... Normal ChiPSC7 ChiPSC7 Y00275 Y00275 ... 20 20-29 Female Europe...us Oct4,SOX2,KLF4,c-Myc ... -- ... Negative ... Yes ... Yes ... Yes G-banding Yes ... Yes ... Takara Bio Europe...an/North African European/North African -- No Cellartis human iPS cell line 7 (ChiPSC7)|Research Grade

Stemcell Information: SKIP001145 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available line derived from a healthy individual peripheral blood. ... 健常人の末梢血由来のヒトiPS細胞株。 human ES-li... Center for iPS Cell Research and Application (CiRA), Kyoto University 京都大学iPS細胞研究所 Center for iPS Cell Rese...arch and Application (CiRA), Kyoto University 京都大学iPS細胞研究所 Yamanaka Shinya 山中 伸弥 Available RIKEN BioResource... SKIP001145 ... Normal HPS0360 HPS0360 648A1 648A1 ... 30 30-39 Male ... -- No Human iPS cell... Center 理化学研究所 バイオリソースセンター ... http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=

Stemcell Information: SKIP000288 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000288 ... mesenchymal stem cell 間葉系幹細胞 Umbilical cord blood 臍帯血 Normal UCB408E6...d-derived mesenchymal stem cells with transgenic hTERT, HPV E6 and E7. Immortalized ... 臍帯血由来間葉系幹細胞, ... 不死化細胞株 fi...evelopment 国立成育医療研究センター研究所 ... Not Available National Institute of Biomedical Innovation. 独立行政法人医薬基盤研究所ＪＣＲＢ細胞バンク http://cell...bank.nibio.go.jp/~cellbank/cgi-bin/search_res_det.cgi?DB_NUM=1&ID...=3374 ... 15647378 ... Immortalization of human fetal cells: the life span of umbilical cord blood-derived cell

Stemcell Information: SKIP000286 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP000286 ... mesenchymal stem cell 間葉系幹細胞 Umbilical cord blood 臍帯血 Normal UCB408E6...医療研究センター研究所 ... Not Available National Institute of Biomedical Innovation. 独立行政法人医薬基盤研究所ＪＣＲＢ細胞バンク http://cellbank.nibio.go.jp/~cell...s with transgenic HPV E6 and E7. finite proliferation 臍帯血由来間葉系幹細胞(有限増殖) fibroblast-li...E7-31 UCB408E6E7-31 JCRB1108 JCRB1108 ... -- -- ... -- No JCRB1108 ... Human umbilical cord blood-derived mesenchymal stem cell...378 ... Immortalization of human fetal cells: the life span of umbilical cord blood-derived cells can be prolon

O vzniku a činnosti SKIP v letech 1968 - 1970

Czech Academy of Sciences Publication Activity Database

Burgetová, Jarmila

2008-01-01

Roč. 17, č. 1 (2008), s. 26-28 ISSN 1210-0927 Institutional research plan: CEZ:AV0Z70830501 Keywords : Association of Library and Information Professionals (SKIP)- foundation in 1968 * Association of Library and Information Professionals (SKIP) - activities in 1968-1970 Subject RIV: AF - Documentation, Librarianship, Information Studies

Stemcell Information: SKIP000222 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available EN-12A HPS0029 HPS0029 ... -- Male ... -- No Human iPS cell line. ヒトiPS細胞株。臍帯由来線維芽細胞由来。 human ES-like... SKIP000222 ... Umbilical cord(Fibroblast) 臍帯（線維芽細胞） Normal HiPS-RIKEN-12A HiPS-RIK... -- Retrovirus Retroviral vector pMXs, Oct3/4, Sox2, Klf4 ... Yes MEF (X-rays:5000R or MMC) 1-1.5x10^(6) cells/...N BRC 理化学研究所バイオリソースセンター Yukio Nakamura 中村幸夫 Available RIKEN BRC 理化学研究所バイオリソースセンター http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0029&type=1 ...

Stemcell Information: SKIP001194 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001194 ... blood mononuclear cell 血中単核細胞 Diseased HPS0508 HPS0508 CiRA00161 Ci... line derived from a patient :Charcot-Marie-Tooth disease . ... シャルコー·マリー·トゥース病患者由来iPS細胞株。 huma...ya 山中 伸弥 Center for iPS Cell Research and Application (CiRA), Kyoto University 京都大学iPS細胞研究所 Center for iPS C...ell Research and Application (CiRA), Kyoto University 京都大学iPS細胞研究所 Yamanaka Shiny...RA00161 シャルコー・マリー・トゥース病 G600 Charcot-Marie-Tooth disease 118210 ... -- -- Japanese 日本人 Yes No Disease specific iPS cell

Stemcell Information: SKIP001001 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available F4,c-Myc ... -- ... Negative ... Yes ... Yes ... Yes G-banding Yes ... Yes ... Takara Bio Europe AB. タカラバイオヨーロッパ...AB Takara Bio Europe AB. タカラバイオヨーロッパAB Takara Bio Europe AB. タカラバイオヨーロッパAB Takara Bio Europe AB. タカラバイオヨーロッパ...AB Not Available Takara Bio Europe AB. タカラバイオヨーロッパAB http://www.clontech.com/JP/Support/Contact_Technical_Support?sitex=10025:22372:US ... takarabio ... SKIP001001 ... Normal P11032 P11032 Y00225 Y00225 ... 38 30-39 Female European/North African Euro...pean/North African -- No Cellartis human iPS cell line P11032|Research Grade(commer

Stemcell Information: SKIP000219 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available l line. ヒトiPS細胞。歯髄細胞由来。 human ES-like -- Plasmid Episomal vector pCXLE, Oct3/4, Sox...Yamanaka 山中伸弥 Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Available RIKE... SKIP000219 ... Pulp 歯髄 Normal 454E2 454E2 HPS0077 HPS0077 ... 16 10-19 Female ... -- No Human iPS cel...2, Klf4, L-Myc, Lin28, p53 shRNA ... Yes SNL 76/7 (X-rays:5000R or MMC) 1.5-2.5x10^(6) cells/100mm dish Primate...N BRC 理化学研究所バイオリソースセンター http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0077&type=1 ...

Stemcell Information: SKIP000277 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available l1 retrotransposition in the neuronal genome in schizophrenia. Bundo M, Toyoshima... SKIP000277 ... Diseased KO-001-25 KO-001-25 ... 統合失調症 F209 Schizophrenia 181500 ... ... |HCV : |その他の感染症 : 梅毒　陰性（梅毒定性RPR（ラテックス比濁法）、梅毒定性TP抗体（ラテックス比濁法）|病歴・治療歴等 : 28歳時、注意力の低下、記憶障害、独語、空笑、幻聴などの精神病症状が亜急性に出現。|　　　　　　　　精神科受診し統合失調症

Stemcell Information: SKIP001193 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001193 ... blood mononuclear cell 血中単核細胞 Diseased HPS0507 HPS0507 CiRA00160 Ci...line derived from a patient :Charcot-Marie-Tooth disease . ... シャルコー·マリー·トゥース病患者由来iPS細胞株。 human ES-like Researc... for iPS Cell Research and Application (CiRA), Kyoto University 京都大学iPS細胞研究所 Center for iPS Cell Research an...d Application (CiRA), Kyoto University 京都大学iPS細胞研究所 Yamanaka Shinya 山中 伸弥 Availab...RA00160 シャルコー・マリー・トゥース病 G600 Charcot-Marie-Tooth disease 118210 ... -- -- Japanese 日本人 Yes No iPS cell

Stemcell Information: SKIP001191 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available SKIP001191 ... blood mononuclear cell 血中単核細胞 Diseased HPS0426 HPS0426 CiRA00139 Ci... line derived from a patient :Charcot-Marie-Tooth disease . シャルコー·マリー·トゥース病患者由来iPS細胞株。 human...a 山中 伸弥 Center for iPS Cell Research and Application (CiRA), Kyoto University 京都大学iPS細胞研究所 Center for iPS Ce...ll Research and Application (CiRA), Kyoto University 京都大学iPS細胞研究所 Yamanaka Shinya...RA00139 シャルコー・マリー・トゥース病 G600 Charcot-Marie-Tooth disease 118210 ... -- -- Japanese 日本人 Yes No Disease specific iPS cell

Stemcell Information: SKIP000678 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ns in the ratio 3:1:1:1:1. 胎児肺線維芽細胞由来iPS細胞。|低酸素下でKlf4, c-Myc, Oct4, Sox2とLIN28を3:...1:1:1:1の割合でコードした合成RNAを、線維芽細胞株に20日間毎日添加し、遺伝子を細胞へ導入した。 human ES-like Research Grade Other OCT4 , SOX2 , KLF4 ,... SKIP000678 ... Lung Lung Normal MRC5-RiPS-1.8 MRC5-RiPS-1.8 ... Fetus Male ... -- No hiPS-cell...s derived from human fetal lung fibroblast cells (MRC-5 Line).They were derived using m....1016/j.stem.2010.08.012 Highly efficient reprogramming to pluripotency and directed differentiation of human cell

Stemcell Information: SKIP000674 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available rous hESC-like colonies in BJ cultures that were mechanically picked at day 18, 20, 21, and 25, respectively. BJ新生児線維芽細胞由来iPS細胞...。|低酸素下でKlf4, c-Myc, Oct4, Sox2とLIN28を3:1:1:1:1の割合でコードした合成RNAを、線維芽細胞株に20日間毎日添加し、遺伝子を細胞へ導入し... SKIP000674 ... foreskin foreskin Normal BJ-RiPS1.1 BJ-RiPS1.1 ... 0-9 Male ... -- No hiPS-cell...cy and directed differentiation of human cells with synthetic modified mRNA.--Som...atic coding mutations in human induced pluripotent stem cells. Warren L, Manos PD, Ahfeldt T, Loh YH, Li H,

Stemcell Information: SKIP000221 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available N-2A HPS0009 HPS0009 ... -- Male ... -- No Human iPS cell line. ヒトiPS細胞。臍帯由来線維芽細胞（RCB0197 HUC-Fm）由来。 ... SKIP000221 ... Umbilical cord(Fibroblast) 臍帯（線維芽細胞） Normal HiPS-RIKEN-2A HiPS-RIKE...human ES-like -- Retrovirus Retroviral vector pMXs, Oct3/4, Sox2, Klf4, c-Myc ... Yes MEF (X-rays:5000R or MMC) 1-1.5x10^(6) cell.../www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0009&type=1 ... ...学研究所バイオリソースセンター RIKEN BRC 理化学研究所バイオリソースセンター Yukio Nakamura 中村幸夫 Available RIKEN BRC 理化学研究所バイオリソースセンター http:/

Skip segment Hirschsprung's disease: a systematic review.

LENUS (Irish Health Repository)

O'Donnell, Anne-Marie

2012-02-01

PURPOSE: Hirschsprung\\'s disease is characterised by the congenital absence of ganglion cells beginning in the distal rectum and extending proximally for varying distances. \\'Zonal aganglionosis\\' is a phenomenon involving a zone of aganglionosis occurring within normally innervated intestine. \\'Skip segment\\' Hirschsprung\\'s disease (SSHD) involves a \\'skip area\\' of normally ganglionated intestine, surrounded proximally and distally by aganglionosis. While Hirschsprung\\'s disease is believed to be the result of incomplete craniocaudal migration of neural crest-derived cells, the occurrence of SSHD has no clear embryological explanation. The aim of this study was to perform a systematic review of SSHD, reported in the literature between 1954 and 2009, in order to determine the clinical characteristics of this rare entity and its significance. METHODS: The first reported case of SSHD was published in 1954. A systematic review of SSHD cases in the literature, from 1954 to 2009, was carried out using the electronic database \\'Pubmed\\'. Detailed information was recorded regarding the age, gender, presenting symptoms and location of the skip segment in each patient. RESULTS: 24 cases of SSHD have been reported in the literature to date. 18\\/24 (75%) of these cases were males and 6\\/24 (25%) were females. Of these, 22\\/24 (92%) were cases of total colonic aganglionosis (TCA), and 2\\/24 (8%) were rectosigmoid Hirschsprung\\'s disease. Of the 22 TCA cases, 9 (41%) had a skip segment in the transverse colon, 6 (27%) in the ascending colon, 2 (9%) in the caecum and 5 (23%) had multiple skip segments. In both rectosigmoid Hirschsprung\\'s disease cases, the skip segment was in the sigmoid colon. Overall, the length of the skip segment was variable, with the entire transverse colon ganglionated in some cases. CONCLUSION: SSHD occurs predominantly in patients with TCA. The existence of a skip area of normally innervated colon in TCA may influence surgical

Social Inequalities in Young Children's Meal Skipping Behaviors: The Generation R Study.

Directory of Open Access Journals (Sweden)

Anne I Wijtzes

Full Text Available Regular meal consumption is considered an important aspect of a healthy diet. While ample evidence shows social inequalities in breakfast skipping among adolescents, little is known about social inequalities in breakfast skipping and skipping of other meals among young school-aged children. Such information is crucial in targeting interventions aimed to promote a healthy diet in children.We examined data from 4704 ethnically diverse children participating in the Generation R Study, a population-based prospective cohort study in Rotterdam, the Netherlands. Information on family socioeconomic position (SEP, ethnic background, and meal skipping behaviors was assessed by parent-reported questionnaire when the child was 6 years old. Multiple logistic regression analyses were performed to assess the associations of family SEP (educational level, household income, employment status, family composition and ethnic background with meal skipping behaviors, using high SEP children and native Dutch children as reference groups.Meal skipping prevalence ranged from 3% (dinner to 11% (lunch. The prevalence of meal skipping was higher among low SEP children and ethnic minority children. Maternal educational level was independently associated with breakfast skipping ([low maternal educational level] OR: 2.21; 95% CI: 1.24,3.94. Paternal educational level was independently associated with lunch skipping ([low paternal educational level] OR: 1.53; 95% CI: 1.06,2.20 and dinner skipping ([mid-high paternal educational level] OR: 0.39; 95% CI: 0.20,0.76. Household income was independently associated with breakfast skipping ([low income] OR: 2.43, 95% CI: 1.40,4.22 and dinner skipping ([low income] OR: 2.44; 95% CI: 1.22,4.91. In general, ethnic minority children were more likely to skip breakfast, lunch, and dinner compared with native Dutch children. Adjustment for family SEP attenuated the associations of ethnic minority background with meal skipping behaviors

Database Description - SKIP Stemcell Database | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available List Contact us SKIP Stemcell Database Database Description General information of database Database name SKIP Stemcell Database...rsity Journal Search: Contact address http://www.skip.med.keio.ac.jp/en/contact/ Database classification Human Genes and Diseases Dat...abase classification Stemcell Article Organism Taxonomy Name: Homo sapiens Taxonomy ID: 9606 Database...ks: Original website information Database maintenance site Center for Medical Genetics, School of medicine, ...lable Web services Not available URL of Web services - Need for user registration Not available About This Database Database

Power inverter implementing phase skipping control

Science.gov (United States)

Somani, Utsav; Amirahmadi, Ahmadreza; Jourdan, Charles; Batarseh, Issa

2016-10-18

A power inverter includes a DC/AC inverter having first, second and third phase circuitry coupled to receive power from a power source. A controller is coupled to a driver for each of the first, second and third phase circuitry (control input drivers). The controller includes an associated memory storing a phase skipping control algorithm, wherein the controller is coupled to receive updating information including a power level generated by the power source. The drivers are coupled to control inputs of the first, second and third phase circuitry, where the drivers are configured for receiving phase skipping control signals from the controller and outputting mode selection signals configured to dynamically select an operating mode for the DC/AC inverter from a Normal Control operation and a Phase Skipping Control operation which have different power injection patterns through the first, second and third phase circuitry depending upon the power level.

Stemcell Information: SKIP000783 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available line derived from T cell in Peripheral Blood (TiPS) 正常iPS細胞株（末梢血由来T細胞から樹立(TiPS)） ... human ES-like Resear...5)|8.Feeder Cellの使用: 使用する|　細胞名 : SNL細胞|　使用時の細胞密度 : 1.5 x 10^(6)/10cm dish|　使用前処理方法 : Mitomycin C処理 : 400micr...　Total 50ml|　Aliquot and store at -20 degree|10.パッセージの際の細胞播種時の細胞密度|　Confluentの10c...析 : 未実施|胚葉体形成実験 : 実施　胚葉体形成確認|テラトーマ形成実験 : 未実施|in vitro分化能解析 : 実施　神経への分化確認|マイコプラズマ汚染検査 : 未実施|細胞同定検査（STR多型解析） : 未実施|クローニング : 未実施 ... SKIP000783 ... Normal aTKA9 aTKA9 ... 40 40-49 Male ... -- No Normal iPS cell

Translational and regulatory challenges for exon skipping therapies.

Science.gov (United States)

Aartsma-Rus, Annemieke; Ferlini, Alessandra; Goemans, Nathalie; Pasmooij, Anna M G; Wells, Dominic J; Bushby, Katerine; Vroom, Elizabeth; Balabanov, Pavel

2014-10-01

Several translational challenges are currently impeding the therapeutic development of antisense-mediated exon skipping approaches for rare diseases. Some of these are inherent to developing therapies for rare diseases, such as small patient numbers and limited information on natural history and interpretation of appropriate clinical outcome measures. Others are inherent to the antisense oligonucleotide (AON)-mediated exon skipping approach, which employs small modified DNA or RNA molecules to manipulate the splicing process. This is a new approach and only limited information is available on long-term safety and toxicity for most AON chemistries. Furthermore, AONs often act in a mutation-specific manner, in which case multiple AONs have to be developed for a single disease. A workshop focusing on preclinical development, trial design, outcome measures, and different forms of marketing authorization was organized by the regulatory models and biochemical outcome measures working groups of Cooperation of Science and Technology Action: "Networking towards clinical application of antisense-mediated exon skipping for rare diseases." The workshop included participants from patient organizations, academia, and members of staff from the European Medicine Agency and Medicine Evaluation Board (the Netherlands). This statement article contains the key outcomes of this meeting.

Eye movements and word skipping during reading: Effects of word length and predictability

Science.gov (United States)

Rayner, Keith; Slattery, Timothy J.; Drieghe, Denis; Liversedge, Simon P.

2012-01-01

The extent to which target words were predictable from prior context was varied: half of the target words were predictable and the other half were unpredictable. In addition, the length of the target word varied: the target words were short (4–6 letters), medium (7–9 letters), or long (10–12 letters). Length and predictability both yielded strong effects on the probability of skipping the target words and on the amount of time readers fixated the target words (when they were not skipped). However, there was no interaction in any of the measures examined for either skipping or fixation time. The results demonstrate that word predictability (due to contextual constraint) and word length have strong and independent influences on word skipping and fixation durations. Furthermore, since the long words extended beyond the word identification span, the data indicate that skipping can occur on the basis of partial information in relation to word identity. PMID:21463086

Translational and Regulatory Challenges for Exon Skipping Therapies

NARCIS (Netherlands)

Aartsma-Rus, Annemieke; Ferlini, Alessandra; Goemans, Nathalie; Pasmooij, Anna M. G.; Wells, Dominic J.; Bushby, Katerine; Vroom, Elizabeth; Balabanov, Pavel

2014-01-01

Several translational challenges are currently impeding the therapeutic development of antisense-mediated exon skipping approaches for rare diseases. Some of these are inherent to developing therapies for rare diseases, such as small patient numbers and limited information on natural history and

Skipping of Chinese characters does not rely on word-based processing.

Science.gov (United States)

Lin, Nan; Angele, Bernhard; Hua, Huimin; Shen, Wei; Zhou, Junyi; Li, Xingshan

2018-02-01

Previous eye-movement studies have indicated that people tend to skip extremely high-frequency words in sentence reading, such as "the" in English and "/de" in Chinese. Two alternative hypotheses have been proposed to explain how this frequent skipping happens in Chinese reading: one assumes that skipping happens when the preview has been fully identified at the word level (word-based skipping); the other assumes that skipping happens whenever the preview character is easy to identify regardless of whether lexical processing has been completed or not (character-based skipping). Using the gaze-contingent display change paradigm, we examined the two hypotheses by substituting the preview of the third character of a four-character Chinese word with the high-frequency Chinese character "/de", which should disrupt the ongoing word-level processing. The character-based skipping hypothesis predicts that this manipulation will enhance the skipping probability of the target character (i.e., the third character of the target word), because the character "/de" has much higher character frequency than the original character. The word-based skipping hypothesis instead predicts a reduction of the skipping probability of the target character because the presence of the character "/de" is lexically infelicitous at word level. The results supported the character-based skipping hypothesis, indicating that in Chinese reading the decision of skipping a character can be made before integrating it into a word.

Valence skipping driven superconductivity and charge Kondo effect

International Nuclear Information System (INIS)

Yanagisawa, Takashi; Hase, Izumi

2013-01-01

Highlights: •Valence skipping in metallic compounds can give rise to an unconventional superconductivity. •Several elements in the periodic table show valence skipping (or valence missing), for example, Bi forms the compounds in valence states +3 and +5. •The doping of valence skipping elements will induce superconductivity and this will lead to a possibility of high temperature superconductivity. •We consider the Wolf model with negative-U impurities, and show a phase diagram including superconducting phase. •There is a high temperature region near the boundary. -- Abstract: Valence skipping in metallic compounds can give rise to an unconventional superconductivity. Several elements in the periodic table show valence skipping (or valence missing), for example, Bi forms the compounds in valence states +3 and +5. The doping of valence skipping elements will induce superconductivity and this will lead to a possibility of high temperature superconductivity. We consider the Wolf model with negative-U impurities, and show a phase diagram including superconducting phase. The superconducting state is changed into a metallic state with a local singlet as the attractive interaction |U| increases. There is a high temperature region near the boundary

Frame Filtering and Skipping for Point Cloud Data Video Transmission

Directory of Open Access Journals (Sweden)

Carlos Moreno

2017-01-01

Full Text Available Sensors for collecting 3D spatial data from the real world are becoming more important. They are a prime research area topic and have applications in consumer markets, such as medical, entertainment, and robotics. However, a primary concern with collecting this data is the vast amount of information being generated, and thus, needing to be processed before being transmitted. To address the issue, we propose the use of filtering methods and frame skipping. To collect the 3D spatial data, called point clouds, we used the Microsoft Kinect sensor. In addition, we utilized the Point Cloud Library to process and filter the data being generated by the Kinect. Two different computers were used: a client which collects, filters, and transmits the point clouds; and a server that receives and visualizes the point clouds. The client is also checking for similarity in consecutive frames, skipping those that reach a similarity threshold. In order to compare the filtering methods and test the effectiveness of the frame skipping technique, quality of service (QoS metrics such as frame rate and percentage of filter were introduced. These metrics indicate how well a certain combination of filtering method and frame skipping accomplishes the goal of transmitting point clouds from one location to another. We found that the pass through filter in conjunction with frame skipping provides the best relative QoS. However, results also show that there is still too much data for a satisfactory QoS. For a real-time system to provide reasonable end-to-end quality, dynamic compression and progressive transmission need to be utilized.

Performance Analysis of Stop-Skipping Scheduling Plans in Rail Transit under Time-Dependent Demand.

Science.gov (United States)

Cao, Zhichao; Yuan, Zhenzhou; Zhang, Silin

2016-07-13

Stop-skipping is a key method for alleviating congestion in rail transit, where schedules are sometimes difficult to implement. Several mechanisms have been proposed and analyzed in the literature, but very few performance comparisons are available. This study formulated train choice behavior estimation into the model considering passengers' perception. If a passenger's train path can be identified, this information would be useful for improving the stop-skipping schedule service. Multi-performance is a key characteristic of our proposed five stop-skipping schedules, but quantified analysis can be used to illustrate the different effects of well-known deterministic and stochastic forms. Problems in the novel category of forms were justified in the context of a single line rather than transit network. We analyzed four deterministic forms based on the well-known A/B stop-skipping operating strategy. A stochastic form was innovatively modeled as a binary integer programming problem. We present a performance analysis of our proposed model to demonstrate that stop-skipping can feasibly be used to improve the service of passengers and enhance the elasticity of train operations under demand variations along with an explicit parametric discussion.

Performance Analysis of Stop-Skipping Scheduling Plans in Rail Transit under Time-Dependent Demand

Directory of Open Access Journals (Sweden)

Zhichao Cao

2016-07-01

Full Text Available Stop-skipping is a key method for alleviating congestion in rail transit, where schedules are sometimes difficult to implement. Several mechanisms have been proposed and analyzed in the literature, but very few performance comparisons are available. This study formulated train choice behavior estimation into the model considering passengers’ perception. If a passenger’s train path can be identified, this information would be useful for improving the stop-skipping schedule service. Multi-performance is a key characteristic of our proposed five stop-skipping schedules, but quantified analysis can be used to illustrate the different effects of well-known deterministic and stochastic forms. Problems in the novel category of forms were justified in the context of a single line rather than transit network. We analyzed four deterministic forms based on the well-known A/B stop-skipping operating strategy. A stochastic form was innovatively modeled as a binary integer programming problem. We present a performance analysis of our proposed model to demonstrate that stop-skipping can feasibly be used to improve the service of passengers and enhance the elasticity of train operations under demand variations along with an explicit parametric discussion.

Antisense-induced exon skipping for duplications in Duchenne muscular dystrophy

Directory of Open Access Journals (Sweden)

van Ommen Gert-Jan B

2007-07-01

Full Text Available Abstract Background Antisense-mediated exon skipping is currently one of the most promising therapeutic approaches for Duchenne muscular dystrophy (DMD. Using antisense oligonucleotides (AONs targeting specific exons the DMD reading frame is restored and partially functional dystrophins are produced. Following proof of concept in cultured muscle cells from patients with various deletions and point mutations, we now focus on single and multiple exon duplications. These mutations are in principle ideal targets for this approach since the specific skipping of duplicated exons would generate original, full-length transcripts. Methods Cultured muscle cells from DMD patients carrying duplications were transfected with AONs targeting the duplicated exons, and the dystrophin RNA and protein were analyzed. Results For two brothers with an exon 44 duplication, skipping was, even at suboptimal transfection conditions, so efficient that both exons 44 were skipped, thus generating, once more, an out-of-frame transcript. In such cases, one may resort to multi-exon skipping to restore the reading frame, as is shown here by inducing skipping of exon 43 and both exons 44. By contrast, in cells from a patient with an exon 45 duplication we were able to induce single exon 45 skipping, which allowed restoration of wild type dystrophin. The correction of a larger duplication (involving exons 52 to 62, by combinations of AONs targeting the outer exons, appeared problematic due to inefficient skipping and mistargeting of original instead of duplicated exons. Conclusion The correction of DMD duplications by exon skipping depends on the specific exons targeted. Its options vary from the ideal one, restoring for the first time the true, wild type dystrophin, to requiring more 'classical' skipping strategies, while the correction of multi-exon deletions may need the design of tailored approaches.

26 CFR 26.2662-1 - Generation-skipping transfer tax return requirements.

Science.gov (United States)

2010-04-01

... at death, the executor of the decedent's estate is liable for the tax imposed on that direct skip by...) Direct skip. In the case of a direct skip, on or before the date on which an estate or gift tax return is... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Generation-skipping transfer tax return...

The relation between breakfast skipping and school performance in Adolescents

NARCIS (Netherlands)

Boschloo, A.M.; Ouwehand, C.; Dekker, S.J.; Lee, N.C.; de Groot, R.H.M.; Krabbendam, A.C.; Jolles, J.

2012-01-01

Breakfast skipping is common in adolescents, but research on the effects of breakfast skipping on school performance is scarce. This current cross-sectional survey study of 605 adolescents aged 11-18 years investigated whether adolescents who habitually skip breakfast have lower end-of-term grades

See Before You Jump: Full Recognition of Parafoveal Words Precedes Skips During Reading

Science.gov (United States)

Gordon, Peter C.; Plummer, Patrick; Choi, Wonil

2013-01-01

Serial attention models of eye-movement control during reading were evaluated in an eye-tracking experiment that examined how lexical activation combines with visual information in the parafovea to affect word skipping (where a word is not fixated during first-pass reading). Lexical activation was manipulated by repetition priming created through prime-target pairs embedded within a sentence. The boundary technique (Rayner, 1975) was used to determine whether the target word was fully available during parafoveal preview or whether it was available with transposed letters (e.g., Herman changed to Hreman). With full parafoveal preview, the target word was skipped more frequently when it matched the earlier prime word (i.e., was repeated) than when it did not match the earlier prime word (i.e., was new). With transposed-letter (TL) preview, repetition had no effect on skipping rates despite the great similarity of the TL preview string to the target word and substantial evidence that TL strings activate the words from which they are derived (Perea & Lupker, 2003). These results show that lexically-based skipping is based on full recognition of the letter string in parafoveal preview and does not involve using the contextual constraint to compensate for the reduced information available from the parafovea. These results are consistent with models of eye-movement control during reading in which successive words in a text are processed one at a time (serially) and in which word recognition strongly influences eye movements. PMID:22686842

Skip segment Hirschsprung disease and Waardenburg syndrome

OpenAIRE

Gross, Erica R.; Geddes, Gabrielle C.; McCarrier, Julie A.; Jarzembowski, Jason A.; Arca, Marjorie J.

2015-01-01

Skip segment Hirschsprung disease describes a segment of ganglionated bowel between two segments of aganglionated bowel. It is a rare phenomenon that is difficult to diagnose. We describe a recent case of skip segment Hirschsprung disease in a neonate with a family history of Waardenburg syndrome and the genetic profile that was identified.

The combined unhealthy behaviors of breakfast skipping and smoking are associated with the prevalence of diabetes mellitus.

Science.gov (United States)

Nishiyama, Midori; Muto, Takashi; Minakawa, Toshihiro; Shibata, Toshie

2009-08-01

Skipping breakfast has been considered a representative unhealthy behavior, but there is little information about the combined effects of breakfast skipping and other unhealthy health habits, especially smoking. First this cross-sectional study investigated unhealthy behaviors among breakfast skippers, and then examined the impact of the combined association of skipping breakfast and smoking on health. A total of 1,200 adults living in one Japanese community were sent questionnaires to elicit data on age, gender, breakfast-eating frequency, and other lifestyle habits. A total 603 of people returned their questionnaires (response rate: 50.3%), and 493 (230 men and 263 women) questionnaires were considered appropriate for analysis. Smoking rate in men (mean age, 53.7 years) and women (mean age, 50.4 years) was 41.3%, and 9.5%, respectively. Skipping breakfast was more prevalent in people under age 50 years (p related to other unhealthy behaviors. Binary logistic regression identified current smoking as the most significant factor related to breakfast skipping (3.10, 95%CI 1.50-6.39). Other factors included, age younger than 50 years (3.04, 95%CI 1.31-7.06) and poor sleeping quality (2.06, 95%CI 1.00-4.25). After examining the combined impact of skipping breakfast and smoking, the highest odds ratio for a diagnosis of diabetes mellitus was found among those who smoked and skipped breakfast (4.68, 95% CI: 1.46-15.05). Moreover, skipping breakfast among non-smokers showed a high association with perceived stress (2.83, 95% CI: 1.05-7.61). In conclusion, the combined unhealthy behaviors of skipping breakfast and smoking are associated with the prevalence of diabetes mellitus.

The Relation between Breakfast Skipping and School Performance in Adolescents

Science.gov (United States)

Boschloo, Annemarie; Ouwehand, Carolijn; Dekker, Sanne; Lee, Nikki; de Groot, Renate; Krabbendam, Lydia; Jolles, Jelle

2012-01-01

Breakfast skipping is common in adolescents, but research on the effects of breakfast skipping on school performance is scarce. This current cross-sectional survey study of 605 adolescents aged 11-18 years investigated whether adolescents who habitually skip breakfast have lower end-of-term grades than adolescents who eat breakfast daily.…

Skip segment Hirschsprung disease and Waardenburg syndrome

Directory of Open Access Journals (Sweden)

Erica R. Gross

2015-04-01

Full Text Available Skip segment Hirschsprung disease describes a segment of ganglionated bowel between two segments of aganglionated bowel. It is a rare phenomenon that is difficult to diagnose. We describe a recent case of skip segment Hirschsprung disease in a neonate with a family history of Waardenburg syndrome and the genetic profile that was identified.

Skipping breakfast and associated factors among Brazilian adolescents

Directory of Open Access Journals (Sweden)

Rosemeyre França de Paula FIUZA

Full Text Available ABSTRACT Objective To analyze the prevalence and factors associated with breakfast skipping among adolescents. Methods Cross-sectional study, with adolescents aged 10-17 years, evaluated between 2009 and 2011, belonging to a cohort study in the Central-West region of Brazil. Breakfast skipping was considered as not having breakfast every day. Demographic, socioeconomic, and lifestyle factors were evaluated through a questionnaire. Anthropometric assessment included measurement of weight and height, which were used to classify weight status using body mass index. Poisson regression was used to assess the association of breakfast skipping with demographic and socioeconomic variables, lifestyle factors, and weight status. Results Among 1,716 Brazilian adolescents evaluated, 36.2% reported not consuming breakfast every day, with the highest prevalence among girls (p=0.03. After adjusting for age and economic class, breakfast skipping was associated with not consuming breakfast with parents and morning shift at school, in both genders, and with obesity only in boys. Lifestyle factors such as alcohol consumption, physical activity, diet quality, and smoking were not associated with skipping breakfast. Conclusion The omission of breakfast was observed in more than a third of adolescents, being associated with demographic and lifestyle factors. In the public health perspective, the importance of encouraging the consumption of this meal is highlighted, with actions involving the school environment and the family.

Stemcell Information: SKIP000250 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available line derived from Pompe disease patient. Same patient as HPS0175 and HPS0176. ポンペ病患者由来iPS細胞... SKIP000250 ... Diseased HPS0176 HPS0176 ... ポンペ病 E740 Pompe disease 232300 ... -- -- ... No No iPS cell... ... Riken Bio Resource Center 理研BRC cellこのメールアドレスはスパムボットから保護されています。閲覧するにはJavaScriptを有効にする必要があります。 document.getElementById('cloake546a02b79274e6d99187d16a0e57c26').innerHTML = ''; var prefix = 'ma' + 'il' + 'to'; var path = 'hr' + 'ef' + '='; var addye546a02b79274e6d99187d16a0e57c26 = 'ips' + '@'; addye546a02b79274e6d99187d16a0e57c26 = addye546a02b79274e6d99187d16a0e57c26 + 'brc' + '.' + 'riken' + '.' + 'jp'; var addy_texte546a02b79274e6d99187d16a0e57c26 = 'ips' + '@' + 'brc' + '.' + 'riken' + '.' + 'jp';document.getElementById('cloake546a02b79274e6d99187d16a0e57c26').innerHTML += ''+addy_texte546a02b79274e6d99187d16a0e57c26+''; cellこのメールアドレスはスパムボットから保護されています。閲覧するにはJavaScriptを有効にする必要があります。 document.getElementById('cloak4cb683cb38bb2a5982ddee2e9965027e').innerHTML = ''; var prefix = 'ma' + 'il' + 'to'; var path = 'hr' + 'ef' + '='; var addy4cb683cb38bb2a5982ddee2e9965027e = 'ips' + '@'; addy4cb683cb38bb2a5982ddee2e9965027e = addy4cb683cb38bb2a5982ddee2e9965027e + 'brc' + '.' + 'riken' + '.' + 'jp'; var addy_text4cb683cb38bb2a5982ddee2e9965027e = 'ips' + '@' + 'brc' + '.' + 'riken' + '.' + 'jp';document.getElementById('cloak4cb683cb38bb2a5982ddee2e9965027e').innerHTML += ''+addy_text4cb683cb38bb2a5982ddee2e9965027e+''; Availab...le Riken Bio Resource Center 理研BRC http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=HPS0176&type=1&lang=en ...

Optimized Skip-Stop Metro Line Operation Using Smart Card Data

Directory of Open Access Journals (Sweden)

Peitong Zhang

2017-01-01

Full Text Available Skip-stop operation is a low cost approach to improving the efficiency of metro operation and passenger travel experience. This paper proposes a novel method to optimize the skip-stop scheme for bidirectional metro lines so that the average passenger travel time can be minimized. Different from the conventional “A/B” scheme, the proposed Flexible Skip-Stop Scheme (FSSS can better accommodate spatially and temporally varied passenger demand. A genetic algorithm (GA based approach is then developed to efficiently search for the optimal solution. A case study is conducted based on a real world bidirectional metro line in Shenzhen, China, using the time-dependent passenger demand extracted from smart card data. It is found that the optimized skip-stop operation is able to reduce the average passenger travel time and transit agencies may benefit from this scheme due to energy and operational cost savings. Analyses are made to evaluate the effects of that fact that certain number of passengers fail to board the right train (due to skip operation. Results show that FSSS always outperforms the all-stop scheme even when most passengers of the skipped OD pairs are confused and cannot get on the right train.

Word skipping: effects of word length, predictability, spelling and reading skill.

Science.gov (United States)

Slattery, Timothy J; Yates, Mark

2017-08-31

Readers eyes often skip over words as they read. Skipping rates are largely determined by word length; short words are skipped more than long words. However, the predictability of a word in context also impacts skipping rates. Rayner, Slattery, Drieghe and Liversedge (2011) reported an effect of predictability on word skipping for even long words (10-13 characters) that extend beyond the word identification span. Recent research suggests that better readers and spellers have an enhanced perceptual span (Veldre & Andrews, 2014). We explored whether reading and spelling skill interact with word length and predictability to impact word skipping rates in a large sample (N=92) of average and poor adult readers. Participants read the items from Rayner et al. (2011) while their eye movements were recorded. Spelling skill (zSpell) was assessed using the dictation and recognition tasks developed by Sally Andrews and colleagues. Reading skill (zRead) was assessed from reading speed (words per minute) and accuracy of three 120 word passages each with 10 comprehension questions. We fit linear mixed models to the target gaze duration data and generalized linear mixed models to the target word skipping data. Target word gaze durations were significantly predicted by zRead while, the skipping likelihoods were significantly predicted by zSpell. Additionally, for gaze durations, zRead significantly interacted with word predictability as better readers relied less on context to support word processing. These effects are discussed in relation to the lexical quality hypothesis and eye movement models of reading.

Breakfast-Skipping and Selecting Low-Nutritional-Quality Foods for Breakfast Are Common among Low-Income Urban Children, Regardless of Food Security Status.

Science.gov (United States)

Dykstra, Holly; Davey, Adam; Fisher, Jennifer O; Polonsky, Heather; Sherman, Sandra; Abel, Michelle L; Dale, Lauren C; Foster, Gary D; Bauer, Katherine W

2016-03-01

Universal access to the School Breakfast Program (SBP) is intended to help low-income and food-insecure students overcome barriers to eating breakfast. However, SBP participation is often still low despite universal access. Further information is needed with regard to these children's breakfast behaviors, and in particular breakfast behaviors among youth from food-insecure families, to inform effective breakfast interventions. The objective of this study was to examine breakfast behaviors among a large sample of urban students with universal access to the SBP and to identify differences in breakfast behaviors among children from food-secure compared with food-insecure households. A cross-sectional study of 821 fourth- through sixth-grade students and their parents from 16 schools was conducted. Students reported the foods/drinks selected and location of obtaining food/drink on the morning of data collection, parents reported household food security status using the 6-item Food Security Survey Module, and the school district provided SBP participation data during the fall semester of 2013. Multivariable linear regression models accounting for school-level clustering were used to examine differences in breakfast behaviors across 3 levels of household food security: food secure, low food secure, and very low food secure. Students participated in the SBP 31.2% of possible days, with 13% never participating in the SBP. One-fifth (19.4%) of students purchased something from a corner store for breakfast, and 16.9% skipped breakfast. Forty-six percent of students were food insecure; few differences in breakfast behaviors were observed across levels of food security. Despite universal access to the SBP, participation in the SBP is low. Breakfast skipping and selection of foods of low nutritional quality in the morning are common, regardless of household food security status. Additional novel implementation of the SBP and addressing students' breakfast preferences may be

Research Issues in Information Access.

Science.gov (United States)

Molholt, Pat

1989-01-01

Discusses traditional library approaches to access to information and the possible impact of information technologies, library automation, and artificial intelligence. Access issues raised by these technologies are identified and a research agenda to explore these issues is outlined. (31 references) (CLB)

Clinical characterisation of Becker muscular dystrophy patients predicts favourable outcome in exon-skipping therapy.

Science.gov (United States)

van den Bergen, J C; Schade van Westrum, S M; Dekker, L; van der Kooi, A J; de Visser, M; Wokke, B H A; Straathof, C S; Hulsker, M A; Aartsma-Rus, A; Verschuuren, J J; Ginjaar, H B

2014-01-01

Duchenne and Becker muscular dystrophy (DMD/BMD) are both caused by mutations in the DMD gene. Out-of-frame mutations in DMD lead to absence of the dystrophin protein, while in-frame BMD mutations cause production of internally deleted dystrophin. Clinically, patients with DMD loose ambulance around the age of 12, need ventilatory support at their late teens and die in their third or fourth decade due to pulmonary or cardiac failure. BMD has a more variable disease course. The disease course of patients with BMD with specific mutations could be very informative to predict the outcome of the exon-skipping therapy, aiming to restore the reading-frame in patients with DMD. Patients with BMD with a mutation equalling a DMD mutation after successful exon skipping were selected from the Dutch Dystrophinopathy Database. Information about disease course was gathered through a standardised questionnaire. Cardiac data were collected from medical correspondence and a previous study on cardiac function in BMD. Forty-eight patients were included, representing 11 different mutations. Median age of patients was 43 years (range 6-67). Nine patients were wheelchair users (26-56 years). Dilated cardiomyopathy was present in 7/36 patients. Only one patient used ventilatory support. Three patients had died at the age of 45, 50 and 76 years, respectively. This study provides mutation specific data on the course of disease in patients with BMD. It shows that the disease course of patients with BMD, with a mutation equalling a 'skipped' DMD mutation is relatively mild. This finding strongly supports the potential benefit of exon skipping in patients with DMD.

26 CFR 26.2653-1 - Taxation of multiple skips.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Taxation of multiple skips. 26.2653-1 Section 26.2653-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) ESTATE...-1 Taxation of multiple skips. (a) General rule. If property is held in trust immediately after a GST...

Gait biomechanics of skipping are substantially different than those of running.

Science.gov (United States)

McDonnell, Jessica; Willson, John D; Zwetsloot, Kevin A; Houmard, Joseph; DeVita, Paul

2017-11-07

The inherit injury risk associated with high-impact exercises calls for alternative ways to achieve the benefits of aerobic exercise while minimizing excessive stresses to body tissues. Skipping presents such an alternative, incorporating double support, flight, and single support phases. We used ground reaction forces (GRFs), lower extremity joint torques and powers to compare skipping and running in 20 healthy adults. The two consecutive skipping steps on each limb differed significantly from each other, and from running. Running had the longest step length, the highest peak vertical GRF, peak knee extensor torque, and peak knee negative and positive power and negative and positive work. Skipping had the greater cadence, peak horizontal GRF, peak hip and ankle extensor torques, peak ankle negative power and work, and peak ankle positive power. The second vs first skipping step had the shorter step length, higher cadence, peak horizontal GRF, peak ankle extensor torque, and peak ankle negative power, negative work, and positive power and positive work. The first skipping step utilized predominately net negative joint work (eccentric muscle action) while the second utilized predominately net positive joint work (concentric muscle action). The skipping data further highlight the persistence of net negative work performed at the knee and net positive work performed at the ankle across locomotion gaits. Evidence of step segregation was seen in distribution of the braking and propelling impulses and net work produced across the hip, knee, and ankle joints. Skipping was substantially different than running and was temporally and spatially asymmetrical with successive foot falls partitioned into a dominant function, either braking or propelling whereas running had a single, repeated step in which both braking and propelling actions were performed equally. Copyright © 2017 Elsevier Ltd. All rights reserved.

Skipped spawning in fishes: More common than you might think

DEFF Research Database (Denmark)

Rideout, Rick M.; Tomkiewicz, Jonna

2011-01-01

The traditional view of iteroparity in fishes is one of an annual reproductive cycle that culminates each year in spawning. More recently, a more flexible view of fish reproduction has been adopted, including the potential for mature fish to skip spawning. Here, we review the abundance of recent...... on elemental and isotope signatures. Skipped spawning is most commonly attributed to deficient diet and poor nutritional condition. Advances made in this field of study in recent years include descriptions of hormonal changes that precede and perhaps initiate skipped spawning, the development of life history...

Update History of This Database - SKIP Stemcell Database | LSDB Archive [Life Science Database Archive metadata

Lifescience Database Archive (English)

Full Text Available List Contact us SKIP Stemcell Database Update History of This Database Date Update contents 2017/03/13 SKIP Stemcell Database... English archive site is opened. 2013/03/29 SKIP Stemcell Database ( https://www.skip.med.k...eio.ac.jp/SKIPSearch/top?lang=en ) is opened. About This Database Database Description Download License Update History of This Databa...se Site Policy | Contact Us Update History of This Database - SKIP Stemcell Database | LSDB Archive ...

26 CFR 26.2611-1 - Generation-skipping transfer defined.

Science.gov (United States)

2010-04-01

... AND GIFT TAXES GENERATION-SKIPPING TRANSFER TAX REGULATIONS UNDER THE TAX REFORM ACT OF 1986 § 26.2611... either a direct skip, a taxable distribution, or a taxable termination. See § 26.2612-1 for the definition of these terms. The determination as to whether an event is a GST is made by reference to the most...

Accessibility and inclusion informational

Directory of Open Access Journals (Sweden)

Mônica Sena de Souza

2013-06-01

Full Text Available Introduction: Discusses the role of information professionals in meeting the informational demands of people with disabilities in the information society. The librarian is crucial for the effectiveness and success in the informational inclusion of people with disabilities, considering also continuing education for their professional qualification.Objective: To provide reflections on the role of the librarian in serving users with disabilities, highlighting the need for improvement in information units, identified in the scientific literature with regard to accessibility.Methodology: Literature search, based on a review of literature in books and scientific papers, highlighting the main authors: Adams (2000, Mazzoni (2001 and Sassaki (1997, 2002, 2005.Results: The lack of informational access for people with disabilities hampers their social and political participation, hence, reduces its condition of citizenship.Conclusion: The librarian responsible for seeking continuing education, greater involvement in the events of the area and the constant search for job training, which will reflect on the best service the information needs of users with disabilities.

Textual information access statistical models

CERN Document Server

Gaussier, Eric

2013-01-01

This book presents statistical models that have recently been developed within several research communities to access information contained in text collections. The problems considered are linked to applications aiming at facilitating information access:- information extraction and retrieval;- text classification and clustering;- opinion mining;- comprehension aids (automatic summarization, machine translation, visualization).In order to give the reader as complete a description as possible, the focus is placed on the probability models used in the applications

See before You Jump: Full Recognition of Parafoveal Words Precedes Skips during Reading

Science.gov (United States)

Gordon, Peter C.; Plummer, Patrick; Choi, Wonil

2013-01-01

Serial attention models of eye-movement control during reading were evaluated in an eye-tracking experiment that examined how lexical activation combines with visual information in the parafovea to affect word skipping (where a word is not fixated during first-pass reading). Lexical activation was manipulated by repetition priming created through…

Access to Information and Privacy | IDRC - International ...

International Development Research Centre (IDRC) Digital Library (Canada)

As a Crown corporation, IDRC is subject to Canada's laws on access to information and privacy protection. The following resources will help you learn more about IDRC and the access to information and privacy acts, including instructions for submitting an access to information or privacy act (ATIP) request. IDRC and ATIP ...

Checklist of accessibility in Web informational environments

Directory of Open Access Journals (Sweden)

Christiane Gomes dos Santos

2017-01-01

Full Text Available This research deals with the process of search, navigation and retrieval of information by the person with blindness in web environment, focusing on knowledge of the areas of information recovery and architecture, to understanding the strategies used by these people to access the information on the web. It aims to propose the construction of an accessibility verification instrument, checklist, to be used to analyze the behavior of people with blindness in search actions, navigation and recovery sites and pages. It a research exploratory and descriptive of qualitative nature, with the research methodology, case study - the research to establish a specific study with the simulation of search, navigation and information retrieval using speech synthesis system, NonVisual Desktop Access, in assistive technologies laboratory, to substantiate the construction of the checklist for accessibility verification. It is considered the reliability of performed research and its importance for the evaluation of accessibility in web environment to improve the access of information for people with limited reading in order to be used on websites and pages accessibility check analysis.

Deep Temporal Models using Identity Skip-Connections for Speech Emotion Recognition

NARCIS (Netherlands)

Kim, Jaebok; Englebienne, Gwenn; Truong, Khiet P.; Evers, Vanessa

2017-01-01

Deep architectures using identity skip-connections have demonstrated groundbreaking performance in the field of image classification. Recently, empirical studies suggested that identity skip-connections enable ensemble-like behaviour of shallow networks, and that depth is not a solo ingredient for

Personnel reliability impact on petrochemical facilities monitoring system's failure skipping probability

Science.gov (United States)

Kostyukov, V. N.; Naumenko, A. P.

2017-08-01

The paper dwells upon urgent issues of evaluating impact of actions conducted by complex technological systems operators on their safe operation considering application of condition monitoring systems for elements and sub-systems of petrochemical production facilities. The main task for the research is to distinguish factors and criteria of monitoring system properties description, which would allow to evaluate impact of errors made by personnel on operation of real-time condition monitoring and diagnostic systems for machinery of petrochemical facilities, and find and objective criteria for monitoring system class, considering a human factor. On the basis of real-time condition monitoring concepts of sudden failure skipping risk, static and dynamic error, monitoring systems, one may solve a task of evaluation of impact that personnel's qualification has on monitoring system operation in terms of error in personnel or operators' actions while receiving information from monitoring systems and operating a technological system. Operator is considered as a part of the technological system. Although, personnel's behavior is usually a combination of the following parameters: input signal - information perceiving, reaction - decision making, response - decision implementing. Based on several researches on behavior of nuclear powers station operators in USA, Italy and other countries, as well as on researches conducted by Russian scientists, required data on operator's reliability were selected for analysis of operator's behavior at technological facilities diagnostics and monitoring systems. The calculations revealed that for the monitoring system selected as an example, the failure skipping risk for the set values of static (less than 0.01) and dynamic (less than 0.001) errors considering all related factors of data on reliability of information perception, decision-making, and reaction fulfilled is 0.037, in case when all the facilities and error probability are under

Designing optimum diameter of skip shafts in mines with inclined or steep coal seams

Energy Technology Data Exchange (ETDEWEB)

Durov, E.M.

1981-07-01

This paper discusses methods of increasing depth of operating shaft mines considering optimization of hoisting systems. The following solutions are analyzed: removing mined rock material to the surface, to operating horizon, to the deepest horizon, removing rock to the deepest horizon by enlarging a large diameter borehole. It is suggested that removing rock material to the surface is most economical. This solution is sometimes difficult to implement due to design of mine shafts. If a shaft is equipped with two pairs of skips, or with a pair of skips and two independent skips, one skip or a pair of skips can be removed to form free space for buckets used to hoist mined rock and coal. The bucket moves along rope shaft guides. Analysis of the optimum hoisting systems in shaft mines for coal mines with the following design capacity is carried out: 0.9, 1.2, 1.5 and 1.8 Mmt a year. The following depth of working horizons is evaluated: 600, 800, 1000, 1200, 1400 and 1600 m. It is assumed that coal and rock are hoisted separately. Advance rate ranges from 10 to 50 m/month. The results of analysis are shown in two tables. It is suggested that from the point of view of increasing depth of active mine shafts the following solutions are optimum: 7 m shaft with a system of three independently moving skips (two for coal, one for rock material), and 8 m shaft equipped with a pair of skips and two independent skips (one of the independently moving skips is used for rock hoisting). 4 refs.

Effect of skipping breakfast on subsequent energy intake.

Science.gov (United States)

Levitsky, David A; Pacanowski, Carly R

2013-07-02

The objective was to examine the effect of consuming breakfast on subsequent energy intake. Participants who habitually ate breakfast and those who skipped breakfast were recruited for two studies. Using a randomized crossover design, the first study examined the effect of having participants consume either (a) no breakfast, (b) a high carbohydrate breakfast (335 kcals), or (c) a high fiber breakfast (360 kcals) on three occasions and measured ad libitum intake at lunch. The second study again used a randomized crossover design but with a larger, normal carbohydrate breakfast consumed ad libtum. Intake averaged 624 kcals and subsequent food intake was measured throughout the day. Participants ate only foods served from the Cornell Human Metabolic Research Unit where all foods were weighed before and after consumption. In the first study, neither eating breakfast nor the kind of breakfast consumed had an effect on the amount consumed at lunch despite a reduction in hunger ratings. In the second study, intake at lunch as well as hunger ratings were significantly increased after skipping breakfast (by 144 kcal), leaving a net caloric deficit of 408 kcal by the end of the day. These data are consistent with published literature demonstrating that skipping a meal does not result in accurate energy compensation at subsequent meals and suggests that skipping breakfast may be an effective means to reduce daily energy intake in some adults. Copyright © 2013 Elsevier Inc. All rights reserved.

Is snack consumption associated with meal skipping in children and adolescents? The CASPIAN-IV study.

Science.gov (United States)

Kelishadi, Roya; Mozafarian, Nafiseh; Qorbani, Mostafa; Motlagh, Mohammad Esmaeil; Safiri, Saeid; Ardalan, Gelayol; Keikhah, Mojtaba; Rezaei, Fatemeh; Heshmat, Ramin

2017-06-01

The present inquiry set to assess the relationship between snack consumption and meal skipping in Iranian children and adolescents. Overall, 14,880 students, aged 6-18 years, were selected via multistage cluster sampling method from rural and urban areas of 30 provinces of Iran. A validated questionnaire of food behaviors including questions on snacks consumption and taking/skipping meals was completed. Consuming and skipping meals and their related factors were reported in both crude and adjusted models. Overall, 13,486 students with a mean age of 12.47 ± 3.36 years completed the study (90.6% participation rate). Among them, 32.08, 8.89, and 10.90% skipped breakfast, lunch, and dinner, respectively. Compared to their counterpart groups, the frequency of meal skipping was higher in girls, urban inhabitants, and students in higher school grades (P Snack consumption was associated with an increased odds ratio of meal skipping in many types of snack groups. Meal skipping and snack consumption were frequent among Iranian children and adolescents. Evidence based interventions are proposed to improve the students' eating habits.

Skip cycle method with a valve-control mechanism for spark ignition engines

International Nuclear Information System (INIS)

Baykara, Cemal; Akin Kutlar, O.; Dogru, Baris; Arslan, Hikmet

2017-01-01

Highlights: • A normal four-stroke cycle followed by a skip cycle without gas exchange is tested. • The normal and skipped mode results are compared at equal power levels. • The throttle valve is opened wider, thereby resulting in a higher volumetric efficiency. • The pumping work during the gas exchange decreases significantly. • The fuel consumption (BSFC) is reduced by approximately 14–26% under part load conditions. - Abstract: The efficiency decrease of spark ignition (SI) engines under part-load conditions is a considerable issue. Changing the effective stroke volume based on the load level is one of the methods using to improve the part-load efficiency. In this study, a novel alternative engine valve control technique in order to perform a cycle without gas exchange (skip cycle), is examined. The goal of skip cycle strategy is to reduce the effective stroke volume of an engine under part load conditions by skipping several of the four stroke cycles by cutting off the fuel injection and simultaneously deactivating the inlet and exhaust valves. To achieve the same power level in the skip cycle, the cylinder pressure level reaches higher values compared to those in a normal four stroke cycle operation, but inherently not higher than the maximum one at full load of normal cycle. According to the experimental results, the break specific fuel consumption (BSFC) was reduced by 14–26% at a 1–3 bar break mean effective pressure (BMEP) and a 1200–1800 rpm engine speed of skip cycle operation, in comparison to normal engine operation. The significant decrease in the pumping work from the gas exchange is one of the primary factors for an increase in efficiency under part load conditions. As expected, the fuel consumption reduction rate at lower load conditions was higher. These experimental results indicate a promising potential of the skip cycle system for reducing the fuel consumption under part load conditions.

Cycle-skipping strategies for pumping loss reduction in spark ignition engines: An experimental approach

International Nuclear Information System (INIS)

Yüksek, Levent; Özener, Orkun; Sandalcı, Tarkan

2012-01-01

Highlights: ► A cycle density variation technique called cycle-skipping was applied. ► Effect on fuel consumption and gaseous emissions was investigated. ► Fuel consumption and gaseous tail-pipe emissions improved at partial loading conditions. - Abstract: Spark ignition (SI) engines are widely used for power generation, especially in the automotive industry. SI engines have a lower thermal efficiency than diesel engines due to a lower compression ratio, higher charge-induction work and lower end of compression stroke pressure. A significant amount of charge induction work is lost when an SI engine runs under partial loading conditions. Under partial loading conditions, a lower intake charge is required, which can be theoretically achieved by varying the displacement volume or the stroke number of the engine without using a throttle. Reducing the displacement volume to control the engine load can be achieved by skipping cycles in single-cylinder engines. This study investigates the effect of cycle-skipping strategies on the brake specific fuel consumption (BSFC) and exhaust emissions of an SI engine under partial loading conditions. Three different skipping modes were applied: normal, normal-skip and normal-normal-skip. A significant improvement in BSFC and carbon monoxide emission was obtained by applying cycle-skipping strategies.

Stemcell Information: SKIP000514 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available 岡野　栄之 Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 Department of Physiology..., Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 Hideyuki Okano 岡野　栄之 Inform...ation Only Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 ... 23039195--2493

The relationship between breakfast skipping, chronotype, and glycemic control in type 2 diabetes.

Science.gov (United States)

Reutrakul, Sirimon; Hood, Megan M; Crowley, Stephanie J; Morgan, Mary K; Teodori, Marsha; Knutson, Kristen L

2014-02-01

Breakfast skipping is associated with obesity and an increased risk of type 2 diabetes. Later chronotypes, individuals who have a preference for later bed and wake times, often skip breakfast. The aim of the study was to explore the relationships among breakfast skipping, chronotype, and glycemic control in type 2 diabetes patients. We collected sleep timing and 24-h dietary recall from 194 non-shift-working type 2 diabetes patients who were being followed in outpatient clinics. Mid-sleep time on free days (MSF) was used as an indicator of chronotype. Hemoglobin A1C (HbA1C) values were obtained from medical records. Hierarchical linear regression analyses controlling for demographic, sleep, and dietary variables were computed to determine whether breakfast skipping was associated with HbA1C. Additional regression analyses were performed to test if this association was mediated by chronotype. There were 22 participants (11.3%) who self-reported missing breakfast. Breakfast skippers had significantly higher HbA1C levels, higher body mass indices (BMI), and later MSF than breakfast eaters. Breakfast skipping was significantly associated with higher HbA1C values (B = 0.108, p = 0.01), even after adjusting for age, sex, race, BMI, number of diabetes complications, insulin use, depressive symptoms, perceived sleep debt, and percentage of daily caloric intake at dinner. The relationship between breakfast skipping and HbA1C was partially mediated by chronotype. In summary, breakfast skipping is associated with a later chronotype. Later chronotype and breakfast skipping both contribute to poorer glycemic control, as indicated by higher HbA1C levels. Future studies are needed to confirm these findings and determine whether behavioral interventions targeting breakfast eating or sleep timing may improve glycemic control in patients with type 2 diabetes.

Nuclear information access system

International Nuclear Information System (INIS)

Ham, C. H.; Yang, M. H.; Yoon, S. W.

1998-01-01

The energy supply in the countries, which have abundant energy resources, may not be affected by accepting the assertion of anti-nuclear and environment groups. Anti-nuclear movements in the countries which have little energy resources may cause serious problem in securing energy supply. Especially, it is distinct in Korea because she heavily depends on nuclear energy in electricity supply(nuclear share in total electricity supply is about 40%).The cause of social trouble surrounding nuclear energy is being involved with various circumstances. However, it is very important that we are not aware of the importance of information access and prepared for such a situation from the early stage of nuclear energy's development. In those matter, this paper analyzes the contents of nuclear information access system in France and Japan which have dynamic nuclear development program and presents the direction of the nuclear access regime through comparing Korean status and referring to progresses of the regime

Open Access to essential health care information

Directory of Open Access Journals (Sweden)

Pandey Manoj

2004-12-01

Full Text Available Abstract Open Access publishing is a valuable resource for the synthesis and distribution of essential health care information. This article discusses the potential benefits of Open Access, specifically in terms of Low and Middle Income (LAMI countries in which there is currently a lack of informed health care providers – mainly a consequence of poor availability to information. We propose that without copyright restrictions, Open Access facilitates distribution of the most relevant research and health care information. Furthermore, we suggest that the technology and infrastructure that has been put in place for Open Access could be used to publish download-able manuals, guides or basic handbooks created by healthcare providers in LAMI countries.

Computer method to detect and correct cycle skipping on sonic logs

International Nuclear Information System (INIS)

Muller, D.C.

1985-01-01

A simple but effective computer method has been developed to detect cycle skipping on sonic logs and to replace cycle skips with estimates of correct traveltimes. The method can be used to correct observed traveltime pairs from the transmitter to both receivers. The basis of the method is the linearity of a plot of theoretical traveltime from the transmitter to the first receiver versus theoretical traveltime from the transmitter to the second receiver. Theoretical traveltime pairs are calculated assuming that the sonic logging tool is centered in the borehole, that the borehole diameter is constant, that the borehole fluid velocity is constant, and that the formation is homogeneous. The plot is linear for the full range of possible formation-rock velocity. Plots of observed traveltime pairs from a sonic logging tool are also linear but have a large degree of scatter due to borehole rugosity, sharp boundaries exhibiting large velocity contrasts, and system measurement uncertainties. However, this scatter can be reduced to a level that is less than scatter due to cycle skipping, so that cycle skips may be detected and discarded or replaced with estimated values of traveltime. Advantages of the method are that it can be applied in real time, that it can be used with data collected by existing tools, that it only affects data that exhibit cycle skipping and leaves other data unchanged, and that a correction trace can be generated which shows where cycle skipping occurs and the amount of correction applied. The method has been successfully tested on sonic log data taken in two holes drilled at the Nevada Test Site, Nye County, Nevada

5 CFR 1303.10 - Access to information.

Science.gov (United States)

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Access to information. 1303.10 Section 1303.10 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET ADMINISTRATIVE PROCEDURES PUBLIC INFORMATION PROVISIONS OF THE ADMINISTRATIVE PROCEDURES ACT Procedures § 1303.10 Access to information. (a...

Internet-accessible real-time weather information system

Digital Repository Service at National Institute of Oceanography (India)

Desai, R.G.P.; Joseph, A.; Desa, E.; Mehra, P.; Desa, E.; Gouveia, A.D.

An internet-accessible real-time weather information system has been developed. This system provides real-time accessibility to weather information from a multitude of spatially distributed weather stations. The Internet connectivity also offers...

Stemcell Information: SKIP000675 [SKIP Stemcell Database[Archive

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Full Text Available llular and Molecular Medicine, Children's Hospital Boston Immune Disease Institute, Program in Cellular and Molecular Medicine, Child...ren's Hospital Boston Derrick J. Rossi Derrick J. Rossi Information Only ... 208

Quantitative Antisense Screening and Optimization for Exon 51 Skipping in Duchenne Muscular Dystrophy.

Science.gov (United States)

Echigoya, Yusuke; Lim, Kenji Rowel Q; Trieu, Nhu; Bao, Bo; Miskew Nichols, Bailey; Vila, Maria Candida; Novak, James S; Hara, Yuko; Lee, Joshua; Touznik, Aleksander; Mamchaoui, Kamel; Aoki, Yoshitsugu; Takeda, Shin'ichi; Nagaraju, Kanneboyina; Mouly, Vincent; Maruyama, Rika; Duddy, William; Yokota, Toshifumi

2017-11-01

Duchenne muscular dystrophy (DMD), the most common lethal genetic disorder, is caused by mutations in the dystrophin (DMD) gene. Exon skipping is a therapeutic approach that uses antisense oligonucleotides (AOs) to modulate splicing and restore the reading frame, leading to truncated, yet functional protein expression. In 2016, the US Food and Drug Administration (FDA) conditionally approved the first phosphorodiamidate morpholino oligomer (morpholino)-based AO drug, eteplirsen, developed for DMD exon 51 skipping. Eteplirsen remains controversial with insufficient evidence of its therapeutic effect in patients. We recently developed an in silico tool to design antisense morpholino sequences for exon skipping. Here, we designed morpholino AOs targeting DMD exon 51 using the in silico tool and quantitatively evaluated the effects in immortalized DMD muscle cells in vitro. To our surprise, most of the newly designed morpholinos induced exon 51 skipping more efficiently compared with the eteplirsen sequence. The efficacy of exon 51 skipping and rescue of dystrophin protein expression were increased by up to more than 12-fold and 7-fold, respectively, compared with the eteplirsen sequence. Significant in vivo efficacy of the most effective morpholino, determined in vitro, was confirmed in mice carrying the human DMD gene. These findings underscore the importance of AO sequence optimization for exon skipping. Copyright © 2017 The American Society of Gene and Cell Therapy. Published by Elsevier Inc. All rights reserved.

Relationships between bullying victimization psychological distress and breakfast skipping among boys and girls.

Science.gov (United States)

Sampasa-Kanyinga, Hugues; Willmore, Jacqueline

2015-06-01

The purpose of this study was to further explore the association between bullying victimization and breakfast skipping in children and adolescents. Compared to the previous study, we have used a larger and representative sample of middle and high school students, examined the effect of gender, different forms (physical, verbal, theft/vandalism and cyber) and severity of bullying on breakfast eating behaviour. Data from students (2286 boys and 2859 girls) aged 11 to 19 years (mean ± SD age: 14.6 ± 1.9 years) from the 2013 Ontario Student Drug Use and Health Survey (OSDUHS) were analysed using self-reports of being bullied, diet, psychological distress, demographics, socio-economic status, weight status, and substance use. Results revealed greater odds of breakfast skipping in girl victims of physical, verbal, and cyber bullying, and in boy victims of verbal and cyber bullying. There was a dose-response relationship between experience of both school and cyber bullying victimization and breakfast skipping behaviour for both genders. Mediation analysis indicated that psychological distress fully mediated the relationship between both verbal and physical bullying victimization and breakfast skipping in girls, and partially mediated the relationship between verbal bullying victimization and breakfast skipping in boys. Psychological distress also partially mediated the link between cyber bullying victimization and breakfast skipping in both boys and girls. These results corroborate previous findings on the association between bullying victimization and breakfast skipping in children and adolescents. The strong and consistent associations with different forms of bullying victimization, the dose-response relationship, and the mediating role of psychological distress suggest a causal relationship. Copyright © 2015 Elsevier Ltd. All rights reserved.

Mathematical modeling for optimizing skip-stop rail transit operation strategy using genetic algorithm.

Science.gov (United States)

2012-03-01

"With skip-stop rail transit operation, transit agencies can reduce their operating costs and fleet size, : and passengers can experience reduced in-transit travel times without extra track and technological : improvement. However, since skip-stop op...

Stemcell Information: SKIP000698 [SKIP Stemcell Database[Archive

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Full Text Available lf Jaenisch Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical Research Whitehead Institute for Biomedica...l Research Whitehead Institute for Biomedical Research R...udolf Jaenisch Rudolf Jaenisch Information Only Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical

Stemcell Information: SKIP000699 [SKIP Stemcell Database[Archive

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Full Text Available lf Jaenisch Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical Research Whitehead Institute for Biomedica...l Research Whitehead Institute for Biomedical Research R...udolf Jaenisch Rudolf Jaenisch Information Only Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical

Stemcell Information: SKIP000700 [SKIP Stemcell Database[Archive

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Full Text Available lf Jaenisch Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical Research Whitehead Institute for Biomedica...l Research Whitehead Institute for Biomedical Research R...udolf Jaenisch Rudolf Jaenisch Information Only Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical

Stemcell Information: SKIP000912 [SKIP Stemcell Database[Archive

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Full Text Available ing ... Yes Teratoma formation ... Salvatore Iovino Salvatore Iovino Harvard Medical School Harvar...d Medical School Harvard Medical School Harvard Medical School C. Ronald Kahn C. Ro...nald Kahn Information Only Harvard Medical School Harvard Medical School ... 26831110 10.1073/pnas.15256651

Stemcell Information: SKIP000579 [SKIP Stemcell Database[Archive

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Full Text Available asic fibroblast growth factor) ... Yes ... No ... Yes teratoma formation ... No ... Department of Cardi...ology,Keio University School of Medicine 慶應義塾大学医学部循環器内科 Shinsuke Yuasa 湯浅　慎介 Inform

Breakfast skipping is associated with cyberbullying and school bullying victimization. A school-based cross-sectional study.

Science.gov (United States)

Sampasa-Kanyinga, Hugues; Roumeliotis, Paul; Farrow, Claire V; Shi, Yuanfeng F

2014-08-01

Breakfast skipping is a health concern that has well-known negative consequences physically and psychologically. It is therefore important to understand why children skip breakfast. The purpose of this study was to establish whether the experience of bullying and cyberbullying impacts upon breakfast skipping and to further evaluate whether the inability for youths to cope with bullying victimization affects their mental health (depression), and in turn predicts breakfast skipping. Data were obtained from the Eastern Ontario 2011 Youth Risk Behaviour Survey, a cross-sectional regional school-based survey of middle and high school students (11-20 years old) across the five counties of Eastern Ontario, Canada (N = 3035). Self-reported data about children's experiences of bullying victimization, breakfast eating habits, socio-economical status, depression, and other risk behaviours were analysed. Approximately half of the participants (50.4%) reported not eating breakfast on a regular basis: 26.3% and 24.1% reported often (usually eat breakfast three times or more per week) and frequent (usually eat breakfast twice a week or less) breakfast skipping behaviour, respectively. Victims of both cyberbullying and school bullying presented greater likelihood of often (adjusted relative risk ratio (RR) = 1.55; 95% confidence interval (CI) = 1.17-2.06) and frequent (RR = 1.97; 95% CI = 1.28-3.03) breakfast skipping. Mediation analysis further showed that depression fully mediated the relationship between school bullying victimization and frequent breakfast skipping. Moreover, depression partially mediated the associations between both cyberbullying and school bullying with frequent breakfast skipping. These findings highlight the potential interrelationships between cyberbullying, school bullying and depression in predicting unhealthy breakfast skipping behaviour in children. Copyright © 2014 Elsevier Ltd. All rights reserved.

Stemcell Information: SKIP000983 [SKIP Stemcell Database[Archive

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Full Text Available RT-PCR Rudolf Jaenisch Rudolf Jaenisch Whitehead Institute for Biomedical Researc...h Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical... Research Rudolf Jaenisch Rudolf Jaenisch Information Only Whitehead Institute for Biomedical... Research Whitehead Institute for Biomedical Research ... 24936472 10.1016/j.st

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Full Text Available RT-PCR Rudolf Jaenisch Rudolf Jaenisch Whitehead Institute for Biomedical Researc...h Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical... Research Rudolf Jaenisch Rudolf Jaenisch Information Only Whitehead Institute for Biomedical... Research Whitehead Institute for Biomedical Research ... 24936472 10.1016/j.st

Potential applications of skip SMV with thrust engine

Science.gov (United States)

Wang, Weilin; Savvaris, Al

2016-11-01

This paper investigates the potential applications of Space Maneuver Vehicles (SMV) with skip trajectory. Due to soaring space operations over the past decades, the risk of space debris has considerably increased such as collision risks with space asset, human property on ground and even aviation. Many active debris removal methods have been investigated and in this paper, a debris remediation method is first proposed based on skip SMV. The key point is to perform controlled re-entry. These vehicles are expected to achieve a trans-atmospheric maneuver with thrust engine. If debris is released at altitude below 80 km, debris could be captured by the atmosphere drag force and re-entry interface prediction accuracy is improved. Moreover if the debris is released in a cargo at a much lower altitude, this technique protects high value space asset from break up by the atmosphere and improves landing accuracy. To demonstrate the feasibility of this concept, the present paper presents the simulation results for two specific mission profiles: (1) descent to predetermined altitude; (2) descent to predetermined point (altitude, longitude and latitude). The evolutionary collocation method is adopted for skip trajectory optimization due to its global optimality and high-accuracy. This method is actually a two-step optimization approach based on the heuristic algorithm and the collocation method. The optimal-control problem is transformed into a nonlinear programming problem (NLP) which can be efficiently and accurately solved by the sequential quadratic programming (SQP) procedure. However, such a method is sensitive to initial values. To reduce the sensitivity problem, genetic algorithm (GA) is adopted to refine the grids and provide near optimum initial values. By comparing the simulation data from different scenarios, it is found that skip SMV is feasible in active debris removal and the evolutionary collocation method gives a truthful re-entry trajectory that satisfies the

Stemcell Information: SKIP000697 [SKIP Stemcell Database[Archive

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Full Text Available Southern blot analysis Yes ... Rudolf Jaenisch Rudolf Jaenisch Whitehead Institute for Biomedical Research W...hitehead Institute for Biomedical Research Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical... Research Rudolf Jaenisch Rudolf Jaenisch Information Only Whitehead Institute for Biomedical R...esearch Whitehead Institute for Biomedical Research ... 24936472 10.1016/j.stemc

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Full Text Available outhern blot analysis Yes ... Rudolf Jaenisch Rudolf Jaenisch Whitehead Institute for Biomedical Research Whi...tehead Institute for Biomedical Research Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical... Research Rudolf Jaenisch Rudolf Jaenisch Information Only Whitehead Institute for Biomedical Res...earch Whitehead Institute for Biomedical Research ... 24936472 10.1016/j.stemcr.

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Full Text Available outhern blot analysis Yes ... Rudolf Jaenisch Rudolf Jaenisch Whitehead Institute for Biomedical Research Whi...tehead Institute for Biomedical Research Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical... Research Rudolf Jaenisch Rudolf Jaenisch Information Only Whitehead Institute for Biomedical Res...earch Whitehead Institute for Biomedical Research ... 24936472 10.1016/j.stemcr.

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Full Text Available outhern blot analysis Yes ... Rudolf Jaenisch Rudolf Jaenisch Whitehead Institute for Biomedical Research Whi...tehead Institute for Biomedical Research Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical... Research Rudolf Jaenisch Rudolf Jaenisch Information Only Whitehead Institute for Biomedical Res...earch Whitehead Institute for Biomedical Research ... 24936472 10.1016/j.stemcr.

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Full Text Available ot analysis Yes ... Yes qRT-PCR Rudolf Jaenisch Rudolf Jaenisch Whitehead Institute for Biomedical... Research Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical Resea...rch Whitehead Institute for Biomedical Research Rudolf Jaenisch Rudolf Jaenisch Information Only Whitehead Institute for Biomedical... Research Whitehead Institute for Biomedical Research ... 24936472 10.1016/j.stemcr.

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Full Text Available Jaenisch Rudolf Jaenisch Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical Rese...arch Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical Research Rudolf Jaenisch... Rudolf Jaenisch Information Only Whitehead Institute for Biomedical Research Whi...tehead Institute for Biomedical Research ... 24936472 10.1016/j.stemcr.2014.03.014 Genetic and chemical cor

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Full Text Available qRT-PCR Rudolf Jaenisch Rudolf Jaenisch Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical... Research Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical Research ...Rudolf Jaenisch Rudolf Jaenisch Information Only Whitehead Institute for Biomedical... Research Whitehead Institute for Biomedical Research ... 24936472 10.1016/j.stemcr.2014.03.014 Genetic a

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Full Text Available Jaenisch Rudolf Jaenisch Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical Rese...arch Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical Research Rudolf Jaenisch... Rudolf Jaenisch Information Only Whitehead Institute for Biomedical Research Whi...tehead Institute for Biomedical Research ... 24936472 10.1016/j.stemcr.2014.03.014 Genetic and chemical cor

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Full Text Available es ... Yes qRT-PCR Rudolf Jaenisch Rudolf Jaenisch Whitehead Institute for Biomedical... Research Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical... Research Rudolf Jaenisch Rudolf Jaenisch Information Only Whitehead Institute for Biomedical... Research Whitehead Institute for Biomedical Research ... 24936472 10.1016/j.stemcr.2014.03.014 G

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Full Text Available qRT-PCR Rudolf Jaenisch Rudolf Jaenisch Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical... Research Whitehead Institute for Biomedical Research Whitehead Institute for Biomedical Research ...Rudolf Jaenisch Rudolf Jaenisch Information Only Whitehead Institute for Biomedical... Research Whitehead Institute for Biomedical Research ... 24936472 10.1016/j.stemcr.2014.03.014 Genetic a

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Full Text Available lar and Molecular Medicine, Children's Hospital Boston Immune Disease Institute, ...Program in Cellular and Molecular Medicine, Children's Hospital Boston Derrick J. Rossi Derrick J. Rossi Inf...ormation Only Immune Disease Institute, Program in Cellular and Molecular Medicine, Children's Hospital Bost...on Immune Disease Institute, Program in Cellular and Molecular Medicine, Children's Hospital Boston ... 208

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Full Text Available te, Program in Cellular and Molecular Medicine, Children's Hospital Boston Immune Disease Institute, Program... in Cellular and Molecular Medicine, Children's Hospital Boston Derrick J. Rossi ...Derrick J. Rossi Information Only Immune Disease Institute, Program in Cellular and Molecular Medicine, Children...'s Hospital Boston Immune Disease Institute, Program in Cellular and Molecular Medicine, Children's Hosp

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Full Text Available , Program in Cellular and Molecular Medicine, Children's Hospital Boston Immune Disease Institute, Program i...n Cellular and Molecular Medicine, Children's Hospital Boston Derrick J. Rossi De...rrick J. Rossi Information Only Immune Disease Institute, Program in Cellular and Molecular Medicine, Children...'s Hospital Boston Immune Disease Institute, Program in Cellular and Molecular Medicine, Children's Hospit

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Full Text Available ular and Molecular Medicine, Children's Hospital Boston Immune Disease Institute,... Program in Cellular and Molecular Medicine, Children's Hospital Boston Derrick J. Rossi Derrick J. Rossi In...formation Only Immune Disease Institute, Program in Cellular and Molecular Medicine, Children's Hospital Bos...ton Immune Disease Institute, Program in Cellular and Molecular Medicine, Children's Hospital Boston ... 20

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Full Text Available ... Immune Disease Institute, Program in Cellular and Molecular Medicine, Children's Hospital Boston Immune Di...sease Institute, Program in Cellular and Molecular Medicine, Children's Hospital ...ren's Hospital Boston Immune Disease Institute, Program in Cellular and Molecular Medicine, Children...Boston Derrick J. Rossi Derrick J. Rossi Information Only Immune Disease Institute, Program in Cellular and Molecular Medicine, Child

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Full Text Available am in Cellular and Molecular Medicine, Children's Hospital Boston Immune Disease Institute, Program in Cellu...lar and Molecular Medicine, Children's Hospital Boston Derrick J. Rossi Derrick J.... Rossi Information Only Immune Disease Institute, Program in Cellular and Molecular Medicine, Children's Ho...spital Boston Immune Disease Institute, Program in Cellular and Molecular Medicine, Children's Hospital Bost

Enterprise wide transparent information access

International Nuclear Information System (INIS)

Brown, J.

1995-05-01

The information management needs of the Department of Energy (DOE) represents a fertile domain for the development of highly sophisticated yet intuitive enterprise-wide computing solutions. These solutions must support business operations, research agendas, technology development efforts, decision support, and other application areas with a user base ranging from technical staff to the highest levels of management. One area of primary interest is in the Environmental Restoration and Waste Management Branch of DOE. In this arena, the issue of tracking and managing nuclear waste related to the long legacy of prior defense production and research programs is one of high visibility and great concern. The Tank Waste Information Network System (TWINS) application has been created by the Pacific Northwest Laboratory (PNL) for the DOE to assist in managing and accessing the information related to this mission. The TWINS solution addresses many of the technical issues faced by other efforts to provide integrated information access to a wide variety of stakeholders. TWINS provides secure transparent access to distributed heterogeneous multimedia information sources from around the DOE complex. The users interact with the information through a consistent user interface that presents the desired data in a common format regardless of the structure of the source information. The solutions developed by the TWINS project represent an integration of several technologies and products that can be applied to other mission areas within DOE and other government agencies. These solutions are now being applied to public and private sector problem domains as well. The successful integration and inter-operation of both commercial and custom modules into a flexible and extensible information architecture will help ensure that new problems facing DOE and other clients can be addressed more rapidly in the future by re-use of existing tools and techniques proven viable through the TWINS efforts

49 CFR 633.15 - Access to information.

Science.gov (United States)

2010-10-01

... 49 Transportation 7 2010-10-01 2010-10-01 false Access to information. 633.15 Section 633.15 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROJECT MANAGEMENT OVERSIGHT Project Management Oversight Services § 633.15 Access to information. A recipient of FTA...

Ewing sarcoma of the left big toe with trans-articular skip lesion

Directory of Open Access Journals (Sweden)

Ahmad F. Kamal

2009-06-01

Full Text Available We report the case of the patient who had Ewing Sarcoma in whom radiological and hystopathological appearances revealed a tumor mass in the left big toe along with trans-artikular skip lesion on the left diaphysis of tibia. In Cipto Mangunkusomo Hospital since 1995 until 2004 we have found 20 Ewing sarcoma cases, but only one skip lesion Ewing sarcoma was found. The diagnosis of transarticular skip lesion in association of Ewing sarcoma was confirmed in clinicopathological conferrence. The initial evaluation of all patients included the recording of the medical history, physical examination, and hematological studies. Radiographs of the chest and the site of the primary tumor were made routinely. Systemic staging was performed with use of total-body bone scan. Ray amputation of left big toe and open biopsy from mass of mid-shaft of tibia had been done to confirm the diagnosis. The patient underwent induction chemotherapy and above knee amputation. Ten months after diagnosis, he died because of advanced-distant metastasis. (Med J Indones 2008; 18: 139-44Key words: Ewing sarcoma, trans-articular skip lesion

Stemcell Information: SKIP000666 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available bryoid body formation ... Yes qRT-PCR ... Immune Disease Institute, Program in Cellular and Molecular Medicine, Children...lular and Molecular Medicine, Children's Hospital Boston Derrick J. Rossi Derrick J. Rossi Information Only ...Immune Disease Institute, Program in Cellular and Molecular Medicine, Children's Hospital Boston Immune Dise...ase Institute, Program in Cellular and Molecular Medicine, Children's Hospital Boston ... 20888316--2136882

Stemcell Information: SKIP001065 [SKIP Stemcell Database[Archive

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Full Text Available boratory of Regenerative Biology, South China Institute for Stem Cell Biology and Regenerative Medicine Key ...Laboratory of Regenerative Biology, South China Institute for Stem Cell Biology a...nd Regenerative Medicine ... Information Only Key Laboratory of Regenerative Biology, South China Institute for Stem Cell Biology... and Regenerative Medicine Key Laboratory of Regenerative Biology, South China Institute for Stem Cell Biology

Scientific information: technology, will and access

Directory of Open Access Journals (Sweden)

Ana M. B. Pavani

2007-12-01

Full Text Available This article addresses the access to information from a point of view that relates the evolution of technology to the methods of treating information and to the desire for knowledge. The first part introduces some important events in ancient times, the end of the middle ages/beginning of the modern age and the XIX century. Then, it presents an overview of the current situation of traditional libraries and compares some characteristics with the corresponding ones for digital libraries. It ends by mentioning the international efforts towards open archives and open access to information; it shows examples of positive results.

Potential Association between Breakfast Skipping and Concomitant Late-Night-Dinner Eating with Metabolic Syndrome and Proteinuria in the Japanese Population

Directory of Open Access Journals (Sweden)

Ayano Kutsuma

2014-01-01

Full Text Available Skipping breakfast is considered to be an unhealthy eating habit linked to predispositions to obesity and type 2 diabetes. Because eating dinner late at night can elicit subsequent breakfast skipping, we investigated if skipping breakfast concomitant with late-night-dinner eating (LNDE was associated with metabolic syndrome (MetS and proteinuria in the general Japanese population. We examined self-reported habitual breakfast skipping and LNDE, MetS (modified ATP-III criteria, and proteinuria in a cross-sectional study of 60,800 Japanese adults aged 20–75 years. A total of 14,068 subjects (23.1% skipped breakfast, of whom approximately half (52.8% skipped breakfast alone (without LNDE. The percentages of subjects who skipped breakfast showed a J-shaped relationship with body mass index (BMI. Multivariate logistic regression analysis showed that skipping breakfast concomitant with LNDE (n = 6,645 was significantly associated with MetS and proteinuria, even after adjusting for relevant confounders (odds ratio (95% CI, 1.17 (1.08–1.28, P=0.0003, and 1.37 (1.24–1.52, P<0.0001, resp.. Skipping breakfast alone and LNDE alone were not associated with MetS and proteinuria, respectively. In conclusion, habitual breakfast skipping concomitant with LNDE may represent poorer eating behavior than skipping breakfast alone, associated with MetS, asymptomatic proteinuria, obesity, and low body weight in the general Japanese population.

Potential Association between Breakfast Skipping and Concomitant Late-Night-Dinner Eating with Metabolic Syndrome and Proteinuria in the Japanese Population.

Science.gov (United States)

Kutsuma, Ayano; Nakajima, Kei; Suwa, Kaname

2014-01-01

Skipping breakfast is considered to be an unhealthy eating habit linked to predispositions to obesity and type 2 diabetes. Because eating dinner late at night can elicit subsequent breakfast skipping, we investigated if skipping breakfast concomitant with late-night-dinner eating (LNDE) was associated with metabolic syndrome (MetS) and proteinuria in the general Japanese population. We examined self-reported habitual breakfast skipping and LNDE, MetS (modified ATP-III criteria), and proteinuria in a cross-sectional study of 60,800 Japanese adults aged 20-75 years. A total of 14,068 subjects (23.1%) skipped breakfast, of whom approximately half (52.8%) skipped breakfast alone (without LNDE). The percentages of subjects who skipped breakfast showed a J-shaped relationship with body mass index (BMI). Multivariate logistic regression analysis showed that skipping breakfast concomitant with LNDE (n = 6,645) was significantly associated with MetS and proteinuria, even after adjusting for relevant confounders (odds ratio (95% CI), 1.17 (1.08-1.28), P = 0.0003, and 1.37 (1.24-1.52), P < 0.0001, resp.). Skipping breakfast alone and LNDE alone were not associated with MetS and proteinuria, respectively. In conclusion, habitual breakfast skipping concomitant with LNDE may represent poorer eating behavior than skipping breakfast alone, associated with MetS, asymptomatic proteinuria, obesity, and low body weight in the general Japanese population.

Stemcell Information: SKIP000561 [SKIP Stemcell Database[Archive

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Full Text Available nnear Caroline Kinnear Department of Pediatrics|and dDevelopmental and|Stem Cell Biology, Hospital|for Sick Children..., University|of Toronto Department of Pediatricsand dDevelopmental andStem Cell Biology, Hospitalfor Sick Children...and|Stem Cell Biology, Hospital|for Sick Children, University|of Toronto Department of Pediatricsand dDevelo...pmental andStem Cell Biology, Hospitalfor Sick Children, Universityof Toronto Seema Mital Seema Mital Inform

Stemcell Information: SKIP000562 [SKIP Stemcell Database[Archive

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Full Text Available nnear Caroline Kinnear Department of Pediatrics|and dDevelopmental and|Stem Cell Biology, Hospital|for Sick Children..., University|of Toronto Department of Pediatricsand dDevelopmental andStem Cell Biology, Hospitalfor Sick Children...and|Stem Cell Biology, Hospital|for Sick Children, University|of Toronto Department of Pediatricsand dDevelo...pmental andStem Cell Biology, Hospitalfor Sick Children, Universityof Toronto Seema Mital Seema Mital Inform

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Full Text Available ... Atsushi Tanaka 田中　敦史 Department of Cardiology, Keio University School of Medicine 慶應義塾大学医学部循環器内科 Depart...ment of Cardiology, Keio University School of Medicine 慶應義塾大学医学部循環器内科 Shinsuke Yuasa 湯浅　慎介 Information Only

The information divide: publishing and access issues | Baker ...

African Journals Online (AJOL)

Some global and local developments in information access and the Open Access movement are highlighted, and the National Library of South Africa\\'s interim strategies to bridge the information and digital divide are identified. However, it becomes evident that unless librarians, information consumers, publishers, ...

Stemcell Information: SKIP001129 [SKIP Stemcell Database[Archive

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Full Text Available o University School of Medicine 慶應義塾大学医学部生理学教室 Department of Physiology, Keio University School of Medicine 慶應義塾大学医学...部生理学教室 Hideyuki Okano 岡野栄之 Information Only Department of Physiology, Keio University School of Medicine 慶應義塾大学医学

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Full Text Available o University School of Medicine 慶應義塾大学医学部生理学教室 Department of Physiology, Keio University School of Medicine 慶應義塾大学医学...部生理学教室 Hideyuki Okano 岡野栄之 Information Only Department of Physiology, Keio University School of Medicine 慶應義塾大学医学

Modulating Calcium Signals to Boost AON Exon Skipping for DMD

Science.gov (United States)

2017-10-01

for Public Release; Distribution Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT AON-mediated exon skipping is currently advancing as therapy for DMD...9 9. Appendices…………………………………………………………… 9 1 1. INTRODUCTION AON-AON-mediated exon skipping is currently advancing as therapy for DMD...CDMD inter-group meetings, an annual retreat, and hosting and attending seminars. While not a stated objective of this grant, trainee career

Enhancing access to health information in Africa: a librarian's perspective.

Science.gov (United States)

Gathoni, Nasra

2012-01-01

In recent years, tremendous progress has been made toward providing health information in Africa, in part because of technological advancements. Nevertheless, ensuring that information is accessible, comprehensible, and usable remains problematic, and there remain needs in many settings to address issues such as computer skills, literacy, and the infrastructure to access information. To determine how librarians might play a more strategic role in meeting information needs of health professionals in Africa, the author reviewed key components of information systems pertinent to knowledge management for the health sector, including access to global online resources, capacity to use computer technology for information retrieval, information literacy, and the potential for professional networks to play a role in improving access to and use of information. The author concluded that, in regions that lack adequate information systems, librarians could apply their knowledge and skills to facilitate access and use by information seekers. Ensuring access to and use of health information can also be achieved by engaging organizations and associations working to enhance access to health information, such as the Association for Health Information and Libraries in Africa. These groups can provide assistance through training, dissemination, information repackaging, and other approaches known to improve information literacy.

Stemcell Information: SKIP001130 [SKIP Stemcell Database[Archive

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Full Text Available o University School of Medicine 慶應義塾大学医学部生理学教室 Department of Physiology, Keio University School of Medicine 慶應義塾大学医学部生理学...教室 Hideyuki Okano 岡野栄之 Information Only Department of Physiology, Keio University School of Medicine 慶應義塾大学医学部生理学

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Full Text Available Linzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology ...dicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Johns H...opkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...Linzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...ng, and Department of Gynecology & Obstetrics, Johns Hopkins University School of

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Full Text Available ing and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学研究所バイオリ...ソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information Only RIKEN BioResource Center 理化学

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Full Text Available s Teratoma assay Yes qRT-PCR ... Immune Disease Institute, Program in Cellular and Molecular Medicine, Children...Disease Institute, Program in Cellular and Molecular Medicine, Children's Hospital Boston Immune Disease Ins...titute, Program in Cellular and Molecular Medicine, Children's Hospital Boston ... 20888316--21368825 10.10...nd Molecular Medicine, Children's Hospital Boston Derrick J. Rossi Derrick J. Rossi Information Only Immune ...'s Hospital Boston Immune Disease Institute, Program in Cellular a

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Full Text Available Teratoma assay Yes qRT-PCR ... Immune Disease Institute, Program in Cellular and Molecular Medicine, Children...sease Institute, Program in Cellular and Molecular Medicine, Children's Hospital Boston Immune Disease Insti...tute, Program in Cellular and Molecular Medicine, Children's Hospital Boston ... 20888316--21368825 10.1016...'s Hospital Boston Immune Disease Institute, Program in Cellular and Molecular Medicine, Chil...dren's Hospital Boston Derrick J. Rossi Derrick J. Rossi Information Only Immune Di

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Full Text Available ... Linzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...ing, and Department of Gynecology & Obstetrics, Johns Hopkins University School o...f Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Joh...ns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...eng Linzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology

Stemcell Information: SKIP000530 [SKIP Stemcell Database[Archive

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Full Text Available ... Linzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...ing, and Department of Gynecology & Obstetrics, Johns Hopkins University School o...f Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Joh...ns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...eng Linzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology

Stemcell Information: SKIP000849 [SKIP Stemcell Database[Archive

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Full Text Available Technologies). 健常人由来iPS細胞。 human ES-like Research Grade Sendai virus Oct4, Sox2,Klf4, and c-Myc ... Yes MEF Hu...Chris M. Woodard ... The New York Stem Cell Foundation Research Institute The New York Stem Cell Foundation Research... Institute Scott A. Noggle ... Scott A. Noggle ... The New York Stem Cell Foundation Research Institute The N...ew York Stem Cell Foundation Research Institute Information Only ... 25456120

Stemcell Information: SKIP000866 [SKIP Stemcell Database[Archive

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Full Text Available Jerome Mertens--Fred H. Gage Jiangsu Collaborative Innovation Center for Language Ability, Jiangsu Normal U...niversity--The Salk Institute for Biological Studies, Laboratory of Genetics Jiangsu Collaborative Innovatio...Biological Studies, Laboratory of Genetics Jiangsu Collaborative Innovation Center for Language Ability, Jia...ngsu Normal University--The Salk Institute for Biological Studies, Laboratory of Genetics Jiangsu Collaborat...nstitute for Biological Studies, Laboratory of Genetics Jun Yao--Fred H. Gage Jun Yao--Fred H. Gage Information Only Jiangsu Collabor

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Full Text Available Jerome Mertens--Fred H. Gage Jiangsu Collaborative Innovation Center for Language Ability, Jiangsu Normal U...niversity--The Salk Institute for Biological Studies, Laboratory of Genetics Jiangsu Collaborative Innovatio...Biological Studies, Laboratory of Genetics Jiangsu Collaborative Innovation Center for Language Ability, Jia...ngsu Normal University--The Salk Institute for Biological Studies, Laboratory of Genetics Jiangsu Collaborat...nstitute for Biological Studies, Laboratory of Genetics Jun Yao--Fred H. Gage Jun Yao--Fred H. Gage Information Only Jiangsu Collabor

Stemcell Information: SKIP000869 [SKIP Stemcell Database[Archive

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Full Text Available Jerome Mertens--Fred H. Gage Jiangsu Collaborative Innovation Center for Language Ability, Jiangsu Normal U...niversity--The Salk Institute for Biological Studies, Laboratory of Genetics Jiangsu Collaborative Innovatio...Biological Studies, Laboratory of Genetics Jiangsu Collaborative Innovation Center for Language Ability, Jia...ngsu Normal University--The Salk Institute for Biological Studies, Laboratory of Genetics Jiangsu Collaborat...nstitute for Biological Studies, Laboratory of Genetics Jun Yao--Fred H. Gage Jun Yao--Fred H. Gage Information Only Jiangsu Collabor

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Full Text Available Jerome Mertens--Fred H. Gage Jiangsu Collaborative Innovation Center for Language Ability, Jiangsu Normal U...niversity--The Salk Institute for Biological Studies, Laboratory of Genetics Jiangsu Collaborative Innovatio...Biological Studies, Laboratory of Genetics Jiangsu Collaborative Innovation Center for Language Ability, Jia...ngsu Normal University--The Salk Institute for Biological Studies, Laboratory of Genetics Jiangsu Collaborat...nstitute for Biological Studies, Laboratory of Genetics Jun Yao--Fred H. Gage Jun Yao--Fred H. Gage Information Only Jiangsu Collabor

Stemcell Information: SKIP000524 [SKIP Stemcell Database[Archive

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Full Text Available nzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & ...Obstetrics, Johns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, a...cine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Johns Hop...kins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gyne...nzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology

[Accessible health information: a question of age?].

Science.gov (United States)

Loos, E F

2012-04-01

Aging and digitalisation are important trends which have their impact on information accessibility. Accessible information about products and services is of crucial importance to ensure that all citizens can participate fully as active members of society. Senior citizens who have difficulties using new media run the risk of exclusion in today's information society. Not all senior citizens, however, encounter problems with new media. Not by a long shot. There is much to be said for 'aged heterogeneity', the concept that individual differences increase as people age. In two explorative qualitative case studies related to accessible health information--an important issue for senior citizens--that were conducted in the Netherlands, variables such as gender, education level and frequency of internet use were therefore included in the research design. In this paper, the most important results of these case studies will be discussed. Attention will be also paid to complementary theories (socialisation, life stages) which could explain differences in information search behaviour when using old or new media.

Thread-Skip: An Undefined Common Observation.

Science.gov (United States)

McDermott, Peter; Allan, William DE

When a screw-retained implant prosthesis is removed, a click is heard and a slight axial shift is felt, indicating the screw has been fully removed from the retaining thread. This common observation has never been described in the literature. This article describes the click, and it is proposed it be termed thread-skip.

Stemcell Information: SKIP000526 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available nzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & ...cine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Johns Hop...kins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...nzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...Obstetrics, Johns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecolo

Stemcell Information: SKIP000523 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available nzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & ...cine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Johns Hop...kins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...nzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...Obstetrics, Johns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecolo

Stemcell Information: SKIP000525 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available nzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & ...cine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Obstetrics, Johns Hop...kins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...nzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...Obstetrics, Johns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecolo

Stemcell Information: SKIP000522 [SKIP Stemcell Database[Archive

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Full Text Available ... Yes ... Linzhao Cheng Linzhao Cheng Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...Cell Engineering, and Department of Gynecology & Obstetrics, Johns Hopkins Univer...sity School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology & Ob...stetrics, Johns Hopkins University School of Medicine Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology...ne Linzhao Cheng Linzhao Cheng Information Only Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology

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Full Text Available ujioka 藤岡 剛 RIKEN BioResource Center 理化学研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Naka...mura 中村　幸夫 Information Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973

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Lifescience Database Archive (English)

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Full Text Available ujioka 藤岡 剛 RIKEN BioResource Center 理化学研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Naka...mura 中村　幸夫 Information Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973

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Full Text Available istochemistry ... Yes Differentiation Yes RT-PCR No ... Yes ... Yes RT-PCR ... Tony Hunter Tony Hunter Molecular and Cell Biology... Laboratory, Salk Institute for Biological Studies, La Jolla, United States Molecular and Cell Biology...tes Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, United States Molecular and Cell Biology...ter Tony Hunter Information Only Molecular and Cell Biology Laboratory, Salk Inst...itute for Biological Studies, La Jolla, United States Molecular and Cell Biology Laboratory, Salk Institute

Stemcell Information: SKIP000541 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ved from human foreskin fibroblasts ((ATCC CRL-2522)(Control line with a wildtype ACVR1 gene.) 新生児包皮線維芽細胞(ATCC CRL-2522)由来iPS細胞...。(コントロール(ACVR1（WT))として使用）| -- Research Grade Plasmid Y4 ... Yes SNL feeder cells primate ES cell...究所 ... Information Only ... 24321451 10.1186/1750-1172-8-190 Induced pluripotent stem cells from patients

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Lifescience Database Archive (English)

Full Text Available n/Caucasian -- No Control iPSC derived from HDFs (KURABO (01439)). KURABO(01439)由来iPS細胞。 human ES-like Resea...Noriyuki Tsumaki 妻木　範行 Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Infor...mation Only Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 https://www.cira.kyo

Assessment of Business Information Access Problems in Uganda

Directory of Open Access Journals (Sweden)

Constant Okello-Obura

2007-09-01

Full Text Available Effective utilization of quality business information is crucial in attaining long-term and sustainable economic growth of the Small and Medium Enterprises (SMEs. It is established that SMEs in northern Uganda operate in a business environment that is characterized by fragmented and incomplete information. It is a situation where an awareness of markets, technology, policies, regulations and finance is limited because businesses fail to receive timely business information. This article reports a portion of the results of a larger study using a descriptive design with survey research and other techniques. The study examined the problems SMEs in northern Uganda face in accessing business information; identified problems information providers face in providing business information to the SMEs in the region and attempted to establish whether SMEs in northern Uganda use public libraries in accessing business information as should be expected. The study’s respondents included the SMEs, information providers and business policy makers with the response rate of 87.3%; 72% and 85% respectively. The article proposes strategic interventions for business information to be accessed by the SMEs. It concludes that there is a need for Uganda and, in particular, northern Uganda to develop a strategy for business information access by the SMEs

Using the Internet to access information inflates future use of the Internet to access other information.

Science.gov (United States)

Storm, Benjamin C; Stone, Sean M; Benjamin, Aaron S

2017-07-01

The ways in which people learn, remember, and solve problems have all been impacted by the Internet. The present research explored how people become primed to use the Internet as a form of cognitive offloading. In three experiments, we show that using the Internet to retrieve information alters a person's propensity to use the Internet to retrieve other information. Specifically, participants who used Google to answer an initial set of difficult trivia questions were more likely to decide to use Google when answering a new set of relatively easy trivia questions than were participants who answered the initial questions from memory. These results suggest that relying on the Internet to access information makes one more likely to rely on the Internet to access other information.

Kinematic characteristics of motor patterns in rope skipping

Directory of Open Access Journals (Sweden)

Luiz Henrique da Silva

2009-09-01

Full Text Available Rope skipping seems to be an easy task to be performed. However, careful analysis of this motor skill shows how complex the execution of this task is. The objective of this study was to examine kinematic variables of jump patterns as a function of skipping frequency. Eight male university students performed a sequence of 30 rope jumps using two jump patterns (alternating support of the feet and simultaneous support of the feet at three skipping frequencies (1.5, 1.7,1.9 Hz. Frequencies were determined with a digital metronome and the rope was turned by the student himself. Rope jumping performance was recorded with two digital cameras for 3Danalysis. Passive markers were attached to the rope and to the ankle, knee and hip joints forcollection of the following dependent variables: continuous relative phase, time interval betweenthe loss of contact of the feet with the ground and cross of the rope under the feet of the volunteer,jump height, and rope height. ANOVA showed that for the pattern with alternating support ofthe feet the jump is executed at a lower height. In addition, analysis of the time interval revealeda delay in the withdrawal of the feet for crossing the rope in the case of the jump pattern with simultaneous support of the feet.

Stemcell Information: SKIP000883 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科学研究室 ... Information Only Biomedical Animal Research Lab...say ... No ... Kyoko Miura 三浦恭子 Biomedical Animal Research Laboratory, Institute for Genetic Medicine, ...oratory, Institute for Genetic Medicine, Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科

Stemcell Information: SKIP000882 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科学研究室 ... Information Only Biomedical Animal Research Lab...say ... No ... Kyoko Miura 三浦恭子 Biomedical Animal Research Laboratory, Institute for Genetic Medicine, ...oratory, Institute for Genetic Medicine, Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科

Stemcell Information: SKIP000878 [SKIP Stemcell Database[Archive

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Full Text Available kkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科学研究室 ... Information Only Biomedical Animal Research Labor...y ... No ... Kyoko Miura 三浦恭子 Biomedical Animal Research Laboratory, Institute for Genetic Medicine, Ho...atory, Institute for Genetic Medicine, Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科

Stemcell Information: SKIP000886 [SKIP Stemcell Database[Archive

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Full Text Available Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科学研究室 ... Information Only Biomedical Animal Research Lab...say ... No ... Kyoko Miura 三浦恭子 Biomedical Animal Research Laboratory, Institute for Genetic Medicine, ...oratory, Institute for Genetic Medicine, Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科

Stemcell Information: SKIP000880 [SKIP Stemcell Database[Archive

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Full Text Available Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科学研究室 ... Information Only Biomedical Animal Research Lab...say ... No ... Kyoko Miura 三浦恭子 Biomedical Animal Research Laboratory, Institute for Genetic Medicine, ...oratory, Institute for Genetic Medicine, Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科

Stemcell Information: SKIP000879 [SKIP Stemcell Database[Archive

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Full Text Available kkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科学研究室 ... Information Only Biomedical Animal Research Labor...y ... No ... Kyoko Miura 三浦恭子 Biomedical Animal Research Laboratory, Institute for Genetic Medicine, Ho...atory, Institute for Genetic Medicine, Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科

Stemcell Information: SKIP000881 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科学研究室 ... Information Only Biomedical Animal Research Lab...say ... No ... Kyoko Miura 三浦恭子 Biomedical Animal Research Laboratory, Institute for Genetic Medicine, ...oratory, Institute for Genetic Medicine, Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科

Stemcell Information: SKIP000884 [SKIP Stemcell Database[Archive

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Full Text Available Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科学研究室 ... Information Only Biomedical Animal Research Lab...say ... No ... Kyoko Miura 三浦恭子 Biomedical Animal Research Laboratory, Institute for Genetic Medicine, ...oratory, Institute for Genetic Medicine, Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科

Stemcell Information: SKIP000343 [SKIP Stemcell Database[Archive

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Full Text Available blasts (HDFs)|same patient as eFOP3-2 FOP疾患者由来iSP細胞。|エピソーマル・プラスミドを用いて作製。 -- Research Grade Plasmid Y4 ... Yes SNL feeder cell...s primate ES cell medium(ReproCELL) ... Yes Immunohistochemistry Ye...yoto University 京都大学 再生医科学研究所 ... Information Only ... 24321451 10.1186/1750-1172-8-190 Induced pluripotent stem cell

Stemcell Information: SKIP000834 [SKIP Stemcell Database[Archive

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Full Text Available ... No ... Yes Microarray Hideyuki Okano 岡野栄之 Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学...部　生理学教室 Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学...部　生理学教室 Hideyuki Okano 岡野栄之 Information Only Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学

Stemcell Information: SKIP000829 [SKIP Stemcell Database[Archive

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Full Text Available ... Yes Microarray Hideyuki Okano 岡野栄之 Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学...部　生理学教室 Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理学教室 Hideyuki Okano 岡野...栄之 Information Only Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学

Stemcell Information: SKIP000825 [SKIP Stemcell Database[Archive

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Full Text Available ray Hideyuki Okano 岡野栄之 Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理学教室 Keio... University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理学教室 Hideyuki Okano 岡野栄之 Information ...Only Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理

Stemcell Information: SKIP000833 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... No ... Yes Microarray Hideyuki Okano 岡野栄之 Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学...部　生理学教室 Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学...部　生理学教室 Hideyuki Okano 岡野栄之 Information Only Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学

Skipping breakfast is detrimental for primary school children: cross-sectional analysis of determinants for targeted prevention

Directory of Open Access Journals (Sweden)

Dorothea Kesztyüs

2017-03-01

Full Text Available Abstract Background Skipping breakfast was found to be associated with abdominal obesity in primary school children. The aim of this research was to examine factors associated with skipping breakfast in primary school children in order to develop targeted preventive measures. Methods Baseline data assessment (2010 of a cluster-randomized controlled trial for the evaluation of a school-based health promotion program in primary school children in the state of Baden-Württemberg, Germany. Anthropometric measures of 1,943 primary school children aged 7.1 ± 0.6 years (51.2% boys were conducted according to ISAK-standards (International Standard for Anthropometric Assessment by trained staff. Further information on the health and living conditions of the children and their parents were assessed in parental questionnaires. Generalized linear mixed regression analysis was calculated to define correlates for skipping breakfast in terms of odds ratios (OR and 95% confidence intervals (CI. Results According to the final regression models, significant correlates of skipping breakfast can be divided into modifiable behavioral components (high consumption of soft drinks (OR 2.49, 95% CI 1.81; 3.43, screen media (OR 2.48, 95% CI 1.77; 3.46 and high levels of physical activity (OR 0.64, 95% CI 0.44; 0.93 on the one hand, and more or less static socio-economic factors (migration background (OR 2.81, 95% CI 2.02; 3.91, single parenting (OR 2.13, 95% CI 1.34; 3.40, and high family education level (OR 0.42, 95% CI 0.28; 0.64 on the other hand, and finally individual factors (female gender (OR 1.43, 95% CI 1.03; 1.99 and having a percentage of body fat at or above the 95th percentile (OR 1.47, 95% CI 1.00; 2.17. Conclusion Targeted prevention should aim at health-related behaviors accompanying the habit of skipping breakfast. Focusing on vulnerable groups, characterized by not so easily modifiable socio-economic as well as individual factors, may improve

SparseLeap: Efficient Empty Space Skipping for Large-Scale Volume Rendering

KAUST Repository

Hadwiger, Markus; Al-Awami, Ali K.; Beyer, Johanna; Agus, Marco; Pfister, Hanspeter

2017-01-01

Recent advances in data acquisition produce volume data of very high resolution and large size, such as terabyte-sized microscopy volumes. These data often contain many fine and intricate structures, which pose huge challenges for volume rendering, and make it particularly important to efficiently skip empty space. This paper addresses two major challenges: (1) The complexity of large volumes containing fine structures often leads to highly fragmented space subdivisions that make empty regions hard to skip efficiently. (2) The classification of space into empty and non-empty regions changes frequently, because the user or the evaluation of an interactive query activate a different set of objects, which makes it unfeasible to pre-compute a well-adapted space subdivision. We describe the novel SparseLeap method for efficient empty space skipping in very large volumes, even around fine structures. The main performance characteristic of SparseLeap is that it moves the major cost of empty space skipping out of the ray-casting stage. We achieve this via a hybrid strategy that balances the computational load between determining empty ray segments in a rasterization (object-order) stage, and sampling non-empty volume data in the ray-casting (image-order) stage. Before ray-casting, we exploit the fast hardware rasterization of GPUs to create a ray segment list for each pixel, which identifies non-empty regions along the ray. The ray-casting stage then leaps over empty space without hierarchy traversal. Ray segment lists are created by rasterizing a set of fine-grained, view-independent bounding boxes. Frame coherence is exploited by re-using the same bounding boxes unless the set of active objects changes. We show that SparseLeap scales better to large, sparse data than standard octree empty space skipping.

SparseLeap: Efficient Empty Space Skipping for Large-Scale Volume Rendering

KAUST Repository

Hadwiger, Markus

2017-08-28

Recent advances in data acquisition produce volume data of very high resolution and large size, such as terabyte-sized microscopy volumes. These data often contain many fine and intricate structures, which pose huge challenges for volume rendering, and make it particularly important to efficiently skip empty space. This paper addresses two major challenges: (1) The complexity of large volumes containing fine structures often leads to highly fragmented space subdivisions that make empty regions hard to skip efficiently. (2) The classification of space into empty and non-empty regions changes frequently, because the user or the evaluation of an interactive query activate a different set of objects, which makes it unfeasible to pre-compute a well-adapted space subdivision. We describe the novel SparseLeap method for efficient empty space skipping in very large volumes, even around fine structures. The main performance characteristic of SparseLeap is that it moves the major cost of empty space skipping out of the ray-casting stage. We achieve this via a hybrid strategy that balances the computational load between determining empty ray segments in a rasterization (object-order) stage, and sampling non-empty volume data in the ray-casting (image-order) stage. Before ray-casting, we exploit the fast hardware rasterization of GPUs to create a ray segment list for each pixel, which identifies non-empty regions along the ray. The ray-casting stage then leaps over empty space without hierarchy traversal. Ray segment lists are created by rasterizing a set of fine-grained, view-independent bounding boxes. Frame coherence is exploited by re-using the same bounding boxes unless the set of active objects changes. We show that SparseLeap scales better to large, sparse data than standard octree empty space skipping.

Accessing Sexual and Reproductive Health Information and ...

African Journals Online (AJOL)

Accessing Sexual and Reproductive Health Information and Services: A Mixed Methods Study of Young ... PROMOTING ACCESS TO AFRICAN RESEARCH ... and services in Soweto, South Africa using quantitative and qualitative methods.

Media use as a reason for meal skipping and fast eating in secondary school children.

Science.gov (United States)

Van den Bulck, J; Eggermont, S

2006-04-01

This study examined self-reported meal skipping and eating faster than usual with the goal of watching television or playing computer games. Respondents reported their media use and indicated how often they skipped a meal to watch a favourite television programme or to play a computer game, and how often they ate faster than usual in order to watch television or play a computer game. Respondents were 2546 adolescents of 13 (first year of secondary school) and 16 years (fourth year of secondary school) of age. About one respondent in 10 skipped at least one meal every week for either television viewing or computer game playing. Weekly meal skipping for television viewing occurs more regularly in boys and first-year students, but particularly in teenagers who view 5 h or more daily (15% of the sample). The category of teenagers who play computer games four times a week or more (25.3% of the sample) is at increased risk of meal skipping; those who play more than four times a week are 10 times more likely weekly to skip a meal. A quarter of the adolescents eat faster at least once a week to be able to watch television or play a computer game. Regardless of gender and school year, teenagers' risk of eating faster progressively increases with their use of the media. Those who watch 4 h or more daily are about seven times more likely to skip a meal for television and those who play computer games at least four times a week are nine times more likely weekly to skip a meal. Unhealthy eating habits can be a side effect of heavy or excessive media use. Teenagers' use of television or game computers during nonworking or out-of-school hours partly displaces the amount of time that needs to be spent at meals. Practitioners and educators may try to encourage or restore a pattern of healthful meal consumption habits by reducing the amount of media use, and by supporting parental rule-making regarding children's eating habits and media use.

Stemcell Information: SKIP000812 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available 714)-specific iPSC タナトフォリック骨異形成症(GM00714)患者線維芽細胞由来iPS細胞 human ES-like Research Grade Other Mixture Y4: OCT4,... iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Cell R...esearch and Application, Kyoto University 京都大学iPS細胞研究所 https://www.cira.kyoto-u.a

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Full Text Available ray Hideyuki Okano 岡野栄之 Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理学教室 Keio... University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理学教室 Hideyuki Okano 岡野栄之 Information ...Only Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理学

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Full Text Available ... Yohei Okada 岡田　洋平 Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学部　生理学...教室 Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 Hideyuki O...kano 岡野　栄之 Information Only Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 ...

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Full Text Available University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理学教室 Keio U...niversity, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理学教室 Hideyuki Okano 岡野栄之 Information On...ly Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理学教室 ... 26905201 10.1016/j.s

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Full Text Available lkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information... Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-077

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Full Text Available kaline phosphatase staining and immunocytochemistry ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information On...ly RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-0774.2

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Full Text Available Alkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Informati...on Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-0

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Full Text Available lkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information... Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-077

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Full Text Available lkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information... Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-077

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Full Text Available lkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information... Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-077

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Full Text Available kaline phosphatase staining and immunocytochemistry ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information On...ly RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-0774.2

Stemcell Information: SKIP000660 [SKIP Stemcell Database[Archive

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Full Text Available lkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information... Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-077

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Full Text Available lkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information... Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-077

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Full Text Available lkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information... Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-077

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Full Text Available kaline phosphatase staining and immunocytochemistry ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Information On...ly RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-0774.2

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Full Text Available staining and immunocytochemistry ... Yes Teratoma formation ... Yes ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Informat...ion Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-

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Lifescience Database Archive (English)

Full Text Available Alkaline phosphatase staining and immunocytochemistry ... No ... Yes ... Tsuyoshi Fujioka 藤岡 剛 RIKEN BioResource Center 理化学...研究所バイオリソースセンター RIKEN BioResource Center 理化学研究所バイオリソースセンター Yukio Nakamura 中村　幸夫 Informati...on Only RIKEN BioResource Center 理化学研究所バイオリソースセンター ... 20973836 10.1111/j.1749-0

Stemcell Information: SKIP000813 [SKIP Stemcell Database[Archive

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Full Text Available GM10749)-specific iPSC タナトフォリック骨異形成症(GM10749)患者線維芽細胞由来iPS細胞 human ES-like Research Grade Other Mixture Y4: O... for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Ce...ll Research and Application, Kyoto University 京都大学iPS細胞研究所 https://www.cira.kyoto

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Full Text Available niversity, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理学教室 Keio Un...iversity, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理学教室 Hideyuki Okano 岡野栄之 Information Onl...y Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理学教室 ... 26905201 10.1016/j.st

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Full Text Available Hideyuki Okano 岡野栄之 Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理学教室 Keio Un...iversity, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理学教室 Hideyuki Okano 岡野栄之 Information Onl...y Keio University, School of Medicine, Department of Physiology ... 慶應義塾大学　医学部　生理学教室

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Full Text Available ... Yohei Okada 岡田　洋平 Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学...部　生理学教室 Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 Hideyuki Okan...o 岡野　栄之 Information Only Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 ...

Stemcell Information: SKIP000516 [SKIP Stemcell Database[Archive

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Full Text Available ... Yohei Okada 岡田　洋平 Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学...部　生理学教室 Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 Hideyuki Oka...no 岡野　栄之 Information Only Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 ...

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Full Text Available ... Yohei Okada 岡田　洋平 Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学...部　生理学教室 Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 Hideyuki O...kano 岡野　栄之 Information Only Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 ...

Stemcell Information: SKIP000517 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... Yohei Okada 岡田　洋平 Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学...部　生理学教室 Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 Hideyuki Okan...o 岡野　栄之 Information Only Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 ...

Dynamics of co-transcriptional pre-mRNA folding influences the induction of dystrophin exon skipping by antisense oligonucleotides.

Directory of Open Access Journals (Sweden)

Keng Boon Wee

Full Text Available Antisense oligonucleotides (AONs mediated exon skipping offers potential therapy for Duchenne muscular dystrophy. However, the identification of effective AON target sites remains unsatisfactory for lack of a precise method to predict their binding accessibility. This study demonstrates the importance of co-transcriptional pre-mRNA folding in determining the accessibility of AON target sites for AON induction of selective exon skipping in DMD. Because transcription and splicing occur in tandem, AONs must bind to their target sites before splicing factors. Furthermore, co-transcriptional pre-mRNA folding forms transient secondary structures, which redistributes accessible binding sites. In our analysis, to approximate transcription elongation, a "window of analysis" that included the entire targeted exon was shifted one nucleotide at a time along the pre-mRNA. Possible co-transcriptional secondary structures were predicted using the sequence in each step of transcriptional analysis. A nucleotide was considered "engaged" if it formed a complementary base pairing in all predicted secondary structures of a particular step. Correlation of frequency and localisation of engaged nucleotides in AON target sites accounted for the performance (efficacy and efficiency of 94% of 176 previously reported AONs. Four novel insights are inferred: (1 the lowest frequencies of engaged nucleotides are associated with the most efficient AONs; (2 engaged nucleotides at 3' or 5' ends of the target site attenuate AON performance more than at other sites; (3 the performance of longer AONs is less attenuated by engaged nucleotides at 3' or 5' ends of the target site compared to shorter AONs; (4 engaged nucleotides at 3' end of a short target site attenuates AON efficiency more than at 5' end.

Dual exon skipping in myostatin and dystrophin for Duchenne muscular dystrophy

Directory of Open Access Journals (Sweden)

van Ommen Gert Jan B

2011-04-01

Full Text Available Abstract Background Myostatin is a potent muscle growth inhibitor that belongs to the Transforming Growth Factor-β (TGF-β family. Mutations leading to non functional myostatin have been associated with hypermuscularity in several organisms. By contrast, Duchenne muscular dystrophy (DMD is characterized by a loss of muscle fibers and impaired regeneration. In this study, we aim to knockdown myostatin by means of exon skipping, a technique which has been successfully applied to reframe the genetic defect of dystrophin gene in DMD patients. Methods We targeted myostatin exon 2 using antisense oligonucleotides (AON in healthy and DMD-derived myotubes cultures. We assessed the exon skipping level, transcriptional expression of myostatin and its target genes, and combined myostatin and several dystrophin AONs. These AONs were also applied in the mdx mice models via intramuscular injections. Results Myostatin AON induced exon 2 skipping in cell cultures and to a lower extent in the mdx mice. It was accompanied by decrease in myostatin mRNA and enhanced MYOG and MYF5 expression. Furthermore, combination of myostatin and dystrophin AONs induced simultaneous skipping of both genes. Conclusions We conclude that two AONs can be used to target two different genes, MSTN and DMD, in a straightforward manner. Targeting multiple ligands of TGF-beta family will be more promising as adjuvant therapies for DMD.

DownloadAccess to Information Request form

International Development Research Centre (IDRC) Digital Library (Canada)

PC Forms Inc. 834-4048

To apply for information under the Access to. Information Act, complete this form or a written request mentioning the Act. Describe the information being sought and provide any relevant details necessary to help the International. Development Research Centre (IDRC) find it. If you require assistance, refer to Info Source.

Stemcell Information: SKIP000885 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available chemistry Yes Teratomas forming assay ... Yes G-band analyses ... Kyoko Miura 三浦恭子 Biomedical Animal Res...学研究室 ... Information Only Biomedical Animal Research Laboratory, Institute for Genetic ...earch Laboratory, Institute for Genetic Medicine, Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科...Medicine, Hokkaido University, Hokkaido 北海道大学　遺伝子病制御研究所　動物機能医科学研究室 http://www.igm.hokudai.ac.jp/debanezumi/

Stemcell Information: SKIP001104 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available 0-9 Female ... -- No hiPSC Generation from Peripheral Blood (CD34+) by using non-T medium. 末梢血CD34陽性細胞由来iPS細胞。|T細胞... ... Keisuke Okita 沖田　圭介 Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Info...rmation Only Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞...nerate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells.--Ce

Stemcell Information: SKIP000537 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ).(Control line with a wildtype ACVR1 gene.) ヒト線維芽細胞(Cell Application,Inc. 106-05a Lot No.1388)由来iPS細胞。(コントロ...ール(ACVR1（WT))として使用）| human ES-like Research Grade Retrovirus OCT4, SOX2, KLF4, c-MYC ... Yes SNL feeder cell...s primate ES cell medium(ReproCELL) ... Yes Immunohistochemistry Yes EB formation as...生医科学研究所 ... Information Only ... 24321451 10.1186/1750-1172-8-190 Induced pluripotent stem cell

Stemcell Information: SKIP000842 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available 　栄之 Department of Physiology, Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 Department of Physiology, ...Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 Hideyuki Okano 岡野　栄之 Information Only Department of Phys...iology, Keio University School of Medicine 慶應義塾大学　医学部　生理学教室 ... 26905201 10.1016/j.stemcr.2016.01.010 Funct

Accessible Electronic and Information Technology

Science.gov (United States)

This Policy establishes EPA's responsibilities and procedures for making its Electronic and Information Technology (EIT) products accessible to all people, including people with disabilities, in accordance with Section 508 of the Rehabilitation Act.

Stemcell Information: SKIP000797 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available pe II (ACG2) ... 200610 ... Fetus Female ... Yes No ACG II(GM07892)-specific iPS cells 軟骨無発症患者線維芽細胞(GM07892)由来iPS細胞...PS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Cell Res...earch and Application,Kyoto University 京都大学iPS細胞研究所　CiRA https://www.cira.kyoto-u.ac.jp/e/index.html ... 251...irected conversion and induced pluripotent stem cells. Okada M, Ikegawa S, Morioka M, Yamashita A, Saito A,

Stemcell Information: SKIP000798 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available II (ACG2) ... 200610 ... Fetus Female ... Yes No ACG II(GM07892)-specific iPS cells 軟骨無発生症患者線維芽細胞(GM07892)由来iPS細胞...S Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Cell Rese...arch and Application,Kyoto University 京都大学iPS細胞研究所　CiRA https://www.cira.kyoto-u.ac.jp/e/index.html ... 2518...rected conversion and induced pluripotent stem cells. Okada M, Ikegawa S, Morioka M, Yamashita A, Saito A, S

Electronic information sources access and use for healthcare ...

African Journals Online (AJOL)

Background: Access to and use of electronic information sources for clinical decision is the key to the attainment of health related sustainable goals. Therefore, this study was to assess Electronic Information Sources (EIS) access and use for healthcare service among hospitals of Western Oromia, Ethiopia, 2013. Materials ...

Stemcell Information: SKIP000802 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available pe II (ACG2) ... 200610 ... 0-9 Male ... Yes No ACG II(S2011-46)-specific iPS cells. Ⅱ型コラーゲン異常症患者線維芽細胞(S2011-46)由来iPS細胞...or iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Cell... Research and Application,Kyoto University 京都大学iPS細胞研究所　CiRA https://www.cira.kyoto-u.ac.jp/e/index.html ... ...by directed conversion and induced pluripotent stem cells. Okada M, Ikegawa S, Morioka M, Yamashita A, Saito

Accessibility of women farmers to agricultural information in South ...

African Journals Online (AJOL)

Furthermore, the women farmers were accessible to technical information on improved seeds (x = 2.59), storage methods (x = 2.44), but poor access to operating farm machinery (x =0.49) and weather forecast (x =0.68). With regard to economic information they were accessible to market locations (x =2.40), but had low ...

Public sector information access policies in Europe

NARCIS (Netherlands)

Welle Donker, F.M.

2010-01-01

In the digital age geo-information has become embedded in our daily lives, such as navigation systems, community platforms, real estate information and weather forecasts. Everybody uses geo-information for their day-to-day decision making. Therefore, access to geo-information is of vital importance

Stemcell Information: SKIP000861 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available anese -- No hiPSC Generation from Peripheral Blood by using non-T medium. 末梢血由来iPS細胞。|T細胞の増殖には関与しない培地で作製。 hu...search and Application, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Cell Research and ...Application, Kyoto University 京都大学iPS細胞研究所 ... 23193063--26198166 10.1002/stem.1...293--10.5966/sctm.2014-0219 An efficient nonviral method to generate integration-free human-induced pluripotent stem cell...s from cord blood and peripheral blood cells.--Cell Therapy Using Human Induced Pluripotent Ste

Stemcell Information: SKIP000801 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available type II (ACG2) ... 200610 ... 0-9 Male ... Yes No ACG II(S2011-46)-specific iPS cells. Ⅱ型コラーゲン異常症患者線維芽細胞(S2011-46)由来iPS細胞... for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Ce...ll Research and Application,Kyoto University 京都大学iPS細胞研究所　CiRA https://www.cira.kyoto-u.ac.jp/e/index.html ... ...a by directed conversion and induced pluripotent stem cells. Okada M, Ikegawa S, Morioka M, Yamashita A, Sai

Stemcell Information: SKIP000863 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available nese Japanese -- No hiPSC Generation from Peripheral Blood by using non-T medium. 末梢血由来iPS細胞。|T細胞の増殖には関与しない培...a 沖田　圭介 Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Information Only Cen...ter for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... 231...93063 10.1002/stem.1293 An efficient nonviral method to generate integration-free human-induced pluripotent stem cell...s from cord blood and peripheral blood cells. Okita K, Yamakawa T, Matsumura Y, Sato Y, Amano N, Wa

Stemcell Information: SKIP000804 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available 610 ... 0-9 Male ... Yes No Hypochondrogenesis(S2011-43)-specific iPS cells. Ⅱ型コラーゲン異常症（軟骨低発生症)患者線維芽細胞(S2011-43)由来iPS細胞...r for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS C...ell Research and Application,Kyoto University 京都大学iPS細胞研究所　CiRA https://www.cira.kyoto-u.ac.jp/e/index.html ...ia by directed conversion and induced pluripotent stem cells. Okada M, Ikegawa S, Morioka M, Yamashita A, Sa

Stemcell Information: SKIP000805 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available 610 ... 0-9 Male ... Yes No Hypochondrogenesis(S2011-43)-specific iPS cells. Ⅱ型コラーゲン異常症（軟骨低発生症)患者線維芽細胞(S2011-43)由来iPS細胞...r for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS C...ell Research and Application,Kyoto University 京都大学iPS細胞研究所　CiRA https://www.cira.kyoto-u.ac.jp/e/index.html ...ia by directed conversion and induced pluripotent stem cells. Okada M, Ikegawa S, Morioka M, Yamashita A, Sa

Stemcell Information: SKIP000803 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available 610 ... 0-9 Male ... Yes No Hypochondrogenesis(S2011-43)-specific iPS cells. Ⅱ型コラーゲン異常症（軟骨低発生症)患者線維芽細胞(S2011-43)由来iPS細胞...r for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS C...ell Research and Application,Kyoto University 京都大学iPS細胞研究所　CiRA https://www.cira.kyoto-u.ac.jp/e/index.html ...ia by directed conversion and induced pluripotent stem cells. Okada M, Ikegawa S, Morioka M, Yamashita A, Sa

Stemcell Information: SKIP000796 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available s (iPSCs) 脊髄性筋萎縮症（Coriell GM03813）患者由来のiPS細胞 human ES-like Research Grade Other OCT...(CiRA), Kyoto University 京都大学iPS細胞研究所 ... Information Only Department of Clinical... Application, Center for iPS Cell Research and Application (CiRA), Kyoto University 京都大学iPS細胞研究所 http://www.... ATROPHY I; SMA1 253300 ... 3 0-9 Male ... Yes No SMA patient(Coriell IDs GM03813 Fibroblast)-derived induced pluripotent stem cell...3/4, SOX2, KLF4, L-MYC, LIN28 and p53 shRNA ... Yes SNL or MEF embryonic stem cell m

Stemcell Information: SKIP000862 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available nese Japanese -- No hiPSC Generation from Peripheral Blood by using non-T medium. 末梢血由来iPS細胞。|T細胞の増殖には関与しない培...suke Okita 沖田　圭介 Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Information... Only Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所... ... 23193063 10.1002/stem.1293 An efficient nonviral method to generate integration-free human-induced pluripotent stem cell...s from cord blood and peripheral blood cells. Okita K, Yamakawa T, Matsumura Y, Sato Y, Am

Stemcell Information: SKIP000800 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available type II (ACG2) ... 200610 ... 0-9 Male ... Yes No ACG II(S2011-46)-specific iPS cells. Ⅱ型コラーゲン異常症患者線維芽細胞(S2011-46)由来iPS細胞...r for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS C...ell Research and Application,Kyoto University 京都大学iPS細胞研究所　CiRA https://www.cira.kyoto-u.ac.jp/e/index.html ...ia by directed conversion and induced pluripotent stem cells. Okada M, Ikegawa S, Morioka M, Yamashita A, Sa

Potential Association between Breakfast Skipping and Concomitant Late-Night-Dinner Eating with Metabolic Syndrome and Proteinuria in the Japanese Population

OpenAIRE

Kutsuma, Ayano; Nakajima, Kei; Suwa, Kaname

2014-01-01

Skipping breakfast is considered to be an unhealthy eating habit linked to predispositions to obesity and type 2 diabetes. Because eating dinner late at night can elicit subsequent breakfast skipping, we investigated if skipping breakfast concomitant with late-night-dinner eating (LNDE) was associated with metabolic syndrome (MetS) and proteinuria in the general Japanese population. We examined self-reported habitual breakfast skipping and LNDE, MetS (modified ATP-III criteria), and proteinur...

48 CFR 1509.505-4 - Obtaining access to proprietary information.

Science.gov (United States)

2010-10-01

... proprietary information. 1509.505-4 Section 1509.505-4 Federal Acquisition Regulations System ENVIRONMENTAL....505-4 Obtaining access to proprietary information. Contractors gaining access to confidential business... business information. ...

Immortalized Muscle Cell Model to Test the Exon Skipping Efficacy for Duchenne Muscular Dystrophy

Directory of Open Access Journals (Sweden)

Quynh Nguyen

2017-10-01

Full Text Available Duchenne muscular dystrophy (DMD is a lethal genetic disorder that most commonly results from mutations disrupting the reading frame of the dystrophin (DMD gene. Among the therapeutic approaches employed, exon skipping using antisense oligonucleotides (AOs is one of the most promising strategies. This strategy aims to restore the reading frame, thus producing a truncated, yet functioning dystrophin protein. In 2016, the Food and Drug Administration (FDA conditionally approved the first AO-based drug, eteplirsen (Exondys 51, developed for DMD exon 51 skipping. An accurate and reproducible method to quantify exon skipping efficacy is essential for evaluating the therapeutic potential of different AOs sequences. However, previous in vitro screening studies have been hampered by the limited proliferative capacity and insufficient amounts of dystrophin expressed by primary muscle cell lines that have been the main system used to evaluate AOs sequences. In this paper, we illustrate the challenges associated with primary muscle cell lines and describe a novel approach that utilizes immortalized cell lines to quantitatively evaluate the exon skipping efficacy in in vitro studies.

Access to Information in the Nordic Countries

DEFF Research Database (Denmark)

Jørgensen, Oluf

Access to Information in the Nordic Countries explains and compares the legal rules determining public access to documents and data in Sweden, Finland, Denmark, Norway, and Iceland. In addition, international rules emanating from the United Nations, the Council of Europe and the European Union...

Stemcell Information: SKIP000858 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available to stimulate the proliferation of T cells. 末梢血由来iPS細胞。|T細胞の増殖を刺激する条件で作製を行った。 human ES-like Research Grade P... data suggested that the four iPS clones were derived from αβT cells.|αβT細胞由来であることを確認| ...ication, Kyoto University 京都大学iPS細胞研究所 ... Information Only Center for iPS Cell Research and Application, Kyoto University 京都大学iPS細胞...an-induced pluripotent stem cells from cord blood and peripheral blood cells.--Cell Therapy Using Human Indu... TRA locus and is excised coincident with TRA rearrangement during the maturation of αβT cells. Hence, these

Information Access for Disabled Students

OpenAIRE

Cypaite, Asta; Šerkšnien, Justina; Rudžioniene, Jurgita

2008-01-01

Disabled students who makes relatively small part of the academic society are in risk to disappear among all other students, due to their communication and mobility difficulties have less possibilities to satisfy their needs, ensuring their rights to qualitative studies, equal opportunities in the labor market and social integration. A topic about information accessibility for disabled students is extremely important because of their information exclusion in their study process at the un...

Particle data management-turning data into accessible information

International Nuclear Information System (INIS)

Bonniface, J; Coppins, G J

2007-01-01

The UKAEA has assigned significant resources to the monitoring and retrieval of particles from the vicinity of its site at Dounreay in the north of Scotland. The monitoring, retrieval and analytical processes each generate information that is required for interpretative and record purposes. As significant resources are made available for studying and retrieving particles, the information collected must be managed in a logical, stable and accessible manner to protect the investment in information. If suitable data management procedures are not in place there is a high risk of data loss and duplication, and stakeholders may be unable to discover what information is already available or be unable to access the existing information. UKAEA Dounreay operates a geographic information system (GIS) that interfaces with a data management system known as IMAGES. These systems are used to securely store and access a wide range of environmental data including those relating to particles. A case study is presented illustrating the processes and systems involved with the collection, storage, analysis and distribution of particle data. The advantages gained through use of the GIS system are considered in relation to alternative types of record management system such as paper, and electronic non-spatial systems. It is considered that the GIS system offers very significant benefits in terms of standardisation of data capture, security of storage and increased accessibility of data compared with other systems

Preferred information sources for clinical decision making: critical care nurses' perceptions of information accessibility and usefulness.

Science.gov (United States)

Marshall, Andrea P; West, Sandra H; Aitken, Leanne M

2011-12-01

Variability in clinical practice may result from the use of diverse information sources to guide clinical decisions. In routine clinical practice, nurses privilege information from colleagues over more formal information sources. It is not clear whether similar information-seeking behaviour is exhibited when critical care nurses make decisions about a specific clinical practice, where extensive practice variability exists alongside a developing research base. This study explored the preferred sources of information intensive care nurses used and their perceptions of the accessibility and usefulness of this information for making decisions in clinically uncertain situations specific to enteral feeding practice. An instrumental case study design, incorporating concurrent verbal protocols, Q methodology and focus groups, was used to determine intensive care nurses' perspectives of information use in the resolution of clinical uncertainty. A preference for information from colleagues to support clinical decisions was observed. People as information sources were considered most useful and most accessible in the clinical setting. Text and electronic information sources were seen as less accessible, mainly because of the time required to access the information within the documents. When faced with clinical uncertainty, obtaining information from colleagues allows information to be quickly accessed and applied within the context of a specific clinical presentation. Seeking information from others also provides opportunities for shared decision-making and potential validation of clinical judgment, although differing views may exacerbate clinical uncertainty. The social exchange of clinical information may meet the needs of nurses working in a complex, time-pressured environment but the extent of the evidence base for information passed through verbal communication is unclear. The perceived usefulness and accessibility of information is premised on the ease of use and access

Access to Information About Stuttering and Societal Knowledge of Stuttering

OpenAIRE

Gabel, Rodney; Brackenbury, Tim; Irani, Farzan

2010-01-01

The purpose of this study was to examine societal knowledge of stuttering, access to information sources, and the influence of information sources on knowledge of stuttering. 185 participants from Northwest Ohio were surveyed. Results of the study indicated that the general public varies in their knowledge of stuttering and that majority of participants had not accessed information about stuttering, and the few who had, did so a long time ago. Finally, access to information sources had little...

39 CFR 255.4 - Accessibility to electronic and information technology.

Science.gov (United States)

2010-07-01

... AND INFORMATION TECHNOLOGY § 255.4 Accessibility to electronic and information technology. (a) In... burden, that the electronic and information technology the agency procures allows— (1) Individuals with... 39 Postal Service 1 2010-07-01 2010-07-01 false Accessibility to electronic and information...

NASA Access Mechanism - Graphical user interface information retrieval system

Science.gov (United States)

Hunter, Judy F.; Generous, Curtis; Duncan, Denise

1993-01-01

Access to online information sources of aerospace, scientific, and engineering data, a mission focus for NASA's Scientific and Technical Information Program, has always been limited by factors such as telecommunications, query language syntax, lack of standardization in the information, and the lack of adequate tools to assist in searching. Today, the NASA STI Program's NASA Access Mechanism (NAM) prototype offers a solution to these problems by providing the user with a set of tools that provide a graphical interface to remote, heterogeneous, and distributed information in a manner adaptable to both casual and expert users. Additionally, the NAM provides access to many Internet-based services such as Electronic Mail, the Wide Area Information Servers system, Peer Locating tools, and electronic bulletin boards.

NASA access mechanism: Graphical user interface information retrieval system

Science.gov (United States)

Hunter, Judy; Generous, Curtis; Duncan, Denise

1993-01-01

Access to online information sources of aerospace, scientific, and engineering data, a mission focus for NASA's Scientific and Technical Information Program, has always been limited to factors such as telecommunications, query language syntax, lack of standardization in the information, and the lack of adequate tools to assist in searching. Today, the NASA STI Program's NASA Access Mechanism (NAM) prototype offers a solution to these problems by providing the user with a set of tools that provide a graphical interface to remote, heterogeneous, and distributed information in a manner adaptable to both casual and expert users. Additionally, the NAM provides access to many Internet-based services such as Electronic Mail, the Wide Area Information Servers system, Peer Locating tools, and electronic bulletin boards.

76 FR 77738 - Telecommunications Act Accessibility Guidelines; Electronic and Information Technology...

Science.gov (United States)

2011-12-14

... Telecommunications Act Accessibility Guidelines and its Electronic and Information Technology Accessibility Standards... electronic and information technology covered by Section 508 of the Rehabilitation Act Amendments of 1998. 76.... 2011-07] RIN 3014-AA37 Telecommunications Act Accessibility Guidelines; Electronic and Information...

User-oriented information access by information need recontextualisation and articulation. Application in nuclear criticality safety

International Nuclear Information System (INIS)

Medini, Lionel

2001-01-01

This research thesis addresses the design methodology of a system of access to information which is based on an access to relevant information with respect to user needs. In a first part, the author addresses the various issues related to access to information and to information understanding. The next part addresses the involved methods and tools and presents the operational approach adopted for this research regarding access to information. Different disciplines are addressed (knowledge management, ergonomics and information science) and different technologies are used (W3 and XML, DVP, ActiveX, pdf format and the Adobe suite). In the core chapter, the author reports the design of a LMCE (a multi-user book of electronic knowledge) which allows both hypermedia navigation in knowledge diagrams and a construction of a document query. This design is based on a knowledge-management modelling to define diagrams, on ergonomics modelling for user profile identification, and on information science for a specific indexing of the information system. The prototype can be visualized with a web browser such as Internet Explorer 5. The author reports a first assessment and discusses the contribution of his approach to the problematic of access to information which is to be applied to nuclear criticality safety [fr

Risk of mental health problems in adolescents skipping meals: The Korean National Health and Nutrition Examination Survey 2010 to 2012.

Science.gov (United States)

Lee, Gyungjoo; Han, Kyungdo; Kim, Hyunju

Adolescents frequently skip meals, doing so even more than once per day. This is associated with more mental health problems. This study identified mental health problems' associations with skipping meals and the frequency thereof among adolescents. This cross-sectional population-based study used a data set of 1,413 adolescents from the 2010 to 2012 Korean National Health and Nutrition Examination Survey. Hierarchical multivariable logistic regression was conducted to determine the risk of mental health problems, including stress, depressive mood, and suicidal ideation in relation to skipping meals and the frequency thereof per day. Breakfast skipping significantly increased the risks of stress and depressive mood. Stress, depressive mood, and suicidal ideation were significantly prevalent as the daily frequency of skipping meals increased. Specific strategies should be developed at government or school level to decrease the frequency of skipping meals per day, associated with serious mental health problems in adolescents. Copyright © 2017 Elsevier Inc. All rights reserved.

Technological Innovation and Cooperation for Foreign Information Access Program

Science.gov (United States)

Office of Postsecondary Education, US Department of Education, 2012

2012-01-01

The Technological Innovation and Cooperation for Foreign Information Access (TICFIA) Program supports projects focused on developing innovative technologies for accessing, collecting, organizing, preserving, and disseminating information from foreign sources to address the U.S.' teaching and research needs in international education and foreign…

Information-flow-based Access Control for Virtualized Systems

Directory of Open Access Journals (Sweden)

Dmitriy Aleksandrovich Postoev

2014-12-01

Full Text Available The article is devoted to the method of information-flow-based access control, adopted for virtualized systems. General structure of access control system for virtual infrastructure is proposed.

DIFABLE PERCEPTION FOR ACCESSIBILITY AND INFORMATION OF PUBLIC TRANSPORT IN JAKARTA

Directory of Open Access Journals (Sweden)

Mochdiana Hernawan

2015-02-01

Full Text Available Every human being has equal right for accessing to the transportation. Difable persons that have different ability also have the same right. The provision of the accessibility and information facility in public transport is not fully meet difable need and therefore difable persons have difficulties in accessibility and information while using public transports. This research will investigate the difable perceptions about accessibility and traveler information for the public transport in Jakarta. Questionnaire method will be used for this purpose and then analyzed by Importance Performance Analysis. The improvement for the transport infrastructure and information system will be elaborated. The findings of the research could be used as input for the local authority while planning or re-construction public transport infrastructure and information system so that difable persons become more accessible and convenience. The study results show that the average value of the perceived performance for the accessibility is 2.78 from 5 scales. This means the performance of the accessibility in overall is fairly. For the information facility, the average performance is 3.11 that meaning the performance in overall is good. The respondents required the provision of waiting room for difable persons as a priority. The information about the departure of the vehicle should been improved as priority to be increased. Furthermore, it is obtained that the Customer Satisfaction Index (CSI value for accessibility is 56%. This indicates the entire respondents satisfied sufficiently with the accessibility facility. Also, 62% of the CSI value shows that the respondents satisfied sufficiently with the provided information.

Access to Information About Stuttering and Societal Knowledge of Stuttering.

Science.gov (United States)

Gabel, Rodney; Brackenbury, Tim; Irani, Farzan

2010-08-01

The purpose of this study was to examine societal knowledge of stuttering, access to information sources, and the influence of information sources on knowledge of stuttering. 185 participants from Northwest Ohio were surveyed. Results of the study indicated that the general public varies in their knowledge of stuttering and that majority of participants had not accessed information about stuttering, and the few who had, did so a long time ago. Finally, access to information sources had little influence on knowledge of stuttering. Implications for future research are discussed.

Skipping breakfast and overweight in 2-and 5-year-old Dutch children-the GECKO Drenthe cohort

NARCIS (Netherlands)

Kupers, L. K.; de Pijper, J. J.; Sauer, P. J. J.; Stolk, R. P.; Corpeleijn, E.

Skipping breakfast is associated with higher BMI in children aged 5 years and older. However, not much is known about this association in younger children. In the Dutch GECKO Drenthe birth cohort we examined the association between breakfast skipping and objectively measured overweight at the age of

Livestock Fadama users' access to information on selected livestock ...

African Journals Online (AJOL)

The FUGs members never had access to information on key livestock technologies like artificial insemination, automated feeding, feed formulation and creep feeding. Farmers' number of years of formal education (r = -0.09) and family size (r= 0.09) had no significant relationships with respondents' access to information on ...

48 CFR 1552.235-80 - Access to confidential business information.

Science.gov (United States)

2010-10-01

... business information. 1552.235-80 Section 1552.235-80 Federal Acquisition Regulations System ENVIRONMENTAL... Clauses 1552.235-80 Access to confidential business information. As prescribed in 1535.007-70(g), insert the following clause. Access to Confidential Business Information (OCT 2000) It is not anticipated...

Cd-Rom and Access to Information

OpenAIRE

Chacón Alvarado, Lucía

2011-01-01

The scientific and technological advances in the world and its application in different areas of knowledge have developed a new electronic age.Computers and telecommunications have created a new scenario for libraries and information centers leading to further changes in the use of its collections and its services increased. Libraries and information centers must address these changes because users demand access to information quickly and efficiently.The CD-ROM is a new technology that has be...

breakfast skipping and academic / social development of pupils

African Journals Online (AJOL)

Abasiama Akpan

“Assessment of the effects of skipping breakfast on the children by pupils was the basic ... concludes that since proper feeding is necessary for the child's academic and social development, the ... people feed influence their behaviour in a variety ... J. C. Duruamaku-Dim, Department of Curriculum & Teaching, Faculty of ...

High School Student Information Access and Engineering Design Performance

Science.gov (United States)

Mentzer, Nathan

2014-01-01

Developing solutions to engineering design problems requires access to information. Research has shown that appropriately accessing and using information in the design process improves solution quality. This quasi-experimental study provides two groups of high school students with a design problem in a three hour design experience. One group has…

Skipping on uneven ground: trailing leg adjustments simplify control and enhance robustness.

Science.gov (United States)

Müller, Roy; Andrada, Emanuel

2018-01-01

It is known that humans intentionally choose skipping in special situations, e.g. when descending stairs or when moving in environments with lower gravity than on Earth. Although those situations involve uneven locomotion, the dynamics of human skipping on uneven ground have not yet been addressed. To find the reasons that may motivate this gait, we combined experimental data on humans with numerical simulations on a bipedal spring-loaded inverted pendulum model (BSLIP). To drive the model, the following parameters were estimated from nine subjects skipping across a single drop in ground level: leg lengths at touchdown, leg stiffness of both legs, aperture angle between legs, trailing leg angle at touchdown (leg landing first after flight phase), and trailing leg retraction speed. We found that leg adjustments in humans occur mostly in the trailing leg (low to moderate leg retraction during swing phase, reduced trailing leg stiffness, and flatter trailing leg angle at lowered touchdown). When transferring these leg adjustments to the BSLIP model, the capacity of the model to cope with sudden-drop perturbations increased.

Handover Management in 5G and Beyond: A Topology Aware Skipping Approach

KAUST Repository

Arshad, Rabe

2016-12-21

Network densification is foreseen as a potential solution to fulfill the 5G spectral efficiency requirements. The spectral efficiency is improved by shrinking base stations’ (BSs) footprints, thus improving the spatial frequency reuse and reducing the number of users sharing the resources of each BS. However, the foreseen densification gains are achieved at the expense of increasing handover (HO) rates. Hence, HO rate is a key performance limiting factor that should be carefully considered in densification planning. This paper sheds light on the HO problem that appears in dense 5G networks and proposes an effective solution via topology aware HO skipping. Different skipping techniques are considered and compared with the conventional best connected scheme. To this end, the proposed schemes are validated via the average user rate in downlink single-tier and two-tier cellular networks, which are modeled using the Poisson point process and the Poisson cluster process, respectively. The proposed skipping schemes show up to 47% gains in the average throughput, which would maximize the benefit of network densification.

Handover Management in 5G and Beyond: A Topology Aware Skipping Approach

KAUST Repository

Arshad, Rabe; Elsawy, Hesham; Sorour, Sameh; Al-Naffouri, Tareq Y.; Alouini, Mohamed-Slim

2016-01-01

Network densification is foreseen as a potential solution to fulfill the 5G spectral efficiency requirements. The spectral efficiency is improved by shrinking base stations’ (BSs) footprints, thus improving the spatial frequency reuse and reducing the number of users sharing the resources of each BS. However, the foreseen densification gains are achieved at the expense of increasing handover (HO) rates. Hence, HO rate is a key performance limiting factor that should be carefully considered in densification planning. This paper sheds light on the HO problem that appears in dense 5G networks and proposes an effective solution via topology aware HO skipping. Different skipping techniques are considered and compared with the conventional best connected scheme. To this end, the proposed schemes are validated via the average user rate in downlink single-tier and two-tier cellular networks, which are modeled using the Poisson point process and the Poisson cluster process, respectively. The proposed skipping schemes show up to 47% gains in the average throughput, which would maximize the benefit of network densification.

Transparency of Biobank Access in Canada: An Assessment of Industry Access and the Availability of Information on Access Policies and Resulting Research.

Science.gov (United States)

Gibson, Shannon G; Axler, Renata E; Lemmens, Trudo

2017-12-01

A key issue impacting public trust in biobanks is how these resources are utilized, including who is given access to biobank data and samples. To assess the conditions under which researchers are given access to Canadian biobanks, we reviewed websites and contacted Canadian biobanks to determine the availability of information on access policies and procedures; research resulting from access biobank data and samples; and conditions on private industry access to biobanks. We also conducted expert interviews with key Canadian stakeholders ( n = 11) to obtain their perspectives on biobank transparency and access policies. Among 21 Canadian biobanks, there was wide variation in the access information made publicly available, and the majority of these allowed access by industry applicants. Biobanks should be governed by the principles of transparency, accountability, and accessibility, and attention must be given to the conditions around the commercialization of biobank-based research.

information source accessibility and usage as determinants

African Journals Online (AJOL)

UDS-CAPTURED

1990-04-28

Apr 28, 1990 ... accessibility and business performance of the community banks over a six-year period. The ... relationship with the banks' business performance. ..... Marketing Management ... Effects of the Information on the Business Performance of Banks. ..... 'Information sources used for strategic planning decisions.

Skip Regulates TGF-β1-Induced Extracellular Matrix Degrading Proteases Expression in Human PC-3 Prostate Cancer Cells

Directory of Open Access Journals (Sweden)

Victor Villar

2013-01-01

Full Text Available Purpose. To determine whether Ski-interacting protein (SKIP regulates TGF-β1-stimulated expression of urokinase-type plasminogen activator (uPA, matrix metalloproteinase-9 (MMP-9, and uPA Inhibitor (PAI-1 in the androgen-independent human prostate cancer cell model. Materials and Methods. PC-3 prostate cancer cell line was used. The role of SKIP was evaluated using synthetic small interference RNA (siRNA compounds. The expression of uPA, MMP-9, and PAI-1 was evaluated by zymography assays, RT-PCR, and promoter transactivation analysis. Results. In PC-3 cells TGF-β1 treatment stimulated uPA, PAI-1, and MMP-9 expressions. The knockdown of SKIP in PC-3 cells enhanced the basal level of uPA, and TGF-β1 treatment inhibited uPA production. Both PAI-1 and MMP-9 production levels were increased in response to TGF-β1. The ectopic expression of SKIP inhibited both TGF-β1-induced uPA and MMP-9 promoter transactivation, while PAI-1 promoter response to the factor was unaffected. Conclusions. SKIP regulates the expression of uPA, PAI-1, and MMP-9 stimulated by TGF-β1 in PC-3 cells. Thus, SKIP is implicated in the regulation of extracellular matrix degradation and can therefore be suggested as a novel therapeutic target in prostate cancer treatment.

Impact of breakfast skipping on the health status of the population

Directory of Open Access Journals (Sweden)

Raksha Goyal

2014-01-01

Full Text Available Background: Obesity has become a worldwide epidemic and its prevalence continues to increase at a rapid rate in various populations and across all age-group. The effect of meal skipping, both behaviorally and physiologically, may have an impact on the outcome of weight-loss efforts. Aims and Objectives: Therefore, the aim of this study was to examine the prevalence of breakfast skipping and obesity in subjects. Materials and Methods: A retrospective analysis of the patients visited to a metabolic clinic of the city was done. Results: One hundred and eighty-six eligible subjects were included for the study. A questionnaire was used for data collection which included information regarding dietary factors and exercise schedule/physical activity. A 24-hour dietary recall method was used to assess the amount of food consumed. Anthropometric measurements were taken. Results: Overweight is generally higherin females than males. The prevalence of overweight was higher among those who consumed more than recommended calories than those who were taking recommended or fewer calories per day. The average intake of fat and protein by the study subjects was quite different than the recommended intake of these food items. There was positive association between fat (oil intake and overweight status and a negative association between protein intake and overweight status which was statistically significant. Conclusion: The higher prevalence of overweight and obesity in the present study could be because of imbalance in the diet and faulty food habits prevalent in the region.

Antisense Oligonucleotide-mediated Exon Skipping as a Systemic Therapeutic Approach for Recessive Dystrophic Epidermolysis Bullosa.

Science.gov (United States)

Bremer, Jeroen; Bornert, Olivier; Nyström, Alexander; Gostynski, Antoni; Jonkman, Marcel F; Aartsma-Rus, Annemieke; van den Akker, Peter C; Pasmooij, Anna Mg

2016-10-18

The "generalized severe" form of recessive dystrophic epidermolysis bullosa (RDEB-gen sev) is caused by bi-allelic null mutations in COL7A1, encoding type VII collagen. The absence of type VII collagen leads to blistering of the skin and mucous membranes upon the slightest trauma. Because most patients carry exonic point mutations or small insertions/deletions, most exons of COL7A1 are in-frame, and low levels of type VII collagen already drastically improve the disease phenotype, this gene seems a perfect candidate for antisense oligonucleotide (AON)-mediated exon skipping. In this study, we examined the feasibility of AON-mediated exon skipping in vitro in primary cultured keratinocytes and fibroblasts, and systemically in vivo using a human skin-graft mouse model. We show that treatment with AONs designed against exon 105 leads to in-frame exon 105 skipping at the RNA level and restores type VII collagen protein production in vitro. Moreover, we demonstrate that systemic delivery in vivo induces de novo expression of type VII collagen in skin grafts generated from patient cells. Our data demonstrate strong proof-of-concept for AON-mediated exon skipping as a systemic therapeutic strategy for RDEB.

Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening.

Directory of Open Access Journals (Sweden)

Debra A O'Leary

Full Text Available One therapeutic approach to Duchenne Muscular Dystrophy (DMD recently entering clinical trials aims to convert DMD phenotypes to that of a milder disease variant, Becker Muscular Dystrophy (BMD, by employing antisense oligonucleotides (AONs targeting splice sites, to induce exon skipping and restore partial dystrophin function. In order to search for small molecule and genetic modulators of AON-dependent and independent exon skipping, we screened approximately 10,000 known small molecule drugs, >17,000 cDNA clones, and >2,000 kinase- targeted siRNAs against a 5.6 kb luciferase minigene construct, encompassing exon 71 to exon 73 of human dystrophin. As a result, we identified several enhancers of exon skipping, acting on both the reporter construct as well as endogenous dystrophin in mdx cells. Multiple mechanisms of action were identified, including histone deacetylase inhibition, tubulin modulation and pre-mRNA processing. Among others, the nucleolar protein NOL8 and staufen RNA binding protein homolog 2 (Stau2 were found to induce endogenous exon skipping in mdx cells in an AON-dependent fashion. An unexpected but recurrent theme observed in our screening efforts was the apparent link between the inhibition of cell cycle progression and the induction of exon skipping.

36 CFR 1256.70 - What controls access to national security-classified information?

Science.gov (United States)

2010-07-01

... national security-classified information? 1256.70 Section 1256.70 Parks, Forests, and Public Property... HISTORICAL MATERIALS Access to Materials Containing National Security-Classified Information § 1256.70 What controls access to national security-classified information? (a) The declassification of and public access...

Protein classification using modified n-grams and skip-grams.

Science.gov (United States)

Islam, S M Ashiqul; Heil, Benjamin J; Kearney, Christopher Michel; Baker, Erich J

2018-05-01

Classification by supervised machine learning greatly facilitates the annotation of protein characteristics from their primary sequence. However, the feature generation step in this process requires detailed knowledge of attributes used to classify the proteins. Lack of this knowledge risks the selection of irrelevant features, resulting in a faulty model. In this study, we introduce a supervised protein classification method with a novel means of automating the work-intensive feature generation step via a Natural Language Processing (NLP)-dependent model, using a modified combination of n-grams and skip-grams (m-NGSG). A meta-comparison of cross-validation accuracy with twelve training datasets from nine different published studies demonstrates a consistent increase in accuracy of m-NGSG when compared to contemporary classification and feature generation models. We expect this model to accelerate the classification of proteins from primary sequence data and increase the accessibility of protein characteristic prediction to a broader range of scientists. m-NGSG is freely available at Bitbucket: https://bitbucket.org/sm_islam/mngsg/src. A web server is available at watson.ecs.baylor.edu/ngsg. erich_baker@baylor.edu. Supplementary data are available at Bioinformatics online.

Factors constraining accessibility and usage of information among ...

African Journals Online (AJOL)

Various factors may negatively impact on information acquisition and utilisation. To improve understanding of the determinants of information acquisition and utilisation, this study investigated the factors constraining accessibility and usage of poultry management information in three rural districts of Tanzania. The findings ...

Effects of social determinants on food choice and skipping meals among Turkish adolescents.

Science.gov (United States)

Soyer, Meral Turk; Ergin, Isil; Gursoy, Safak Taner

2008-01-01

To present data that contributes to understanding factors that influence food choice and skipping meals in adolescents. A cross sectional study is carried in selected high schools in Bornova. Study sample compromises of 527 students chosen randomly by class from a population of 2410 first year in high school students. Self-administered questionnaires containing sociodemographic determinants, self reported weight and height, food choices and meal patterns were used. A psychosocial factor that affects almost all of the students is the "taste and sensory perception of food". The second noticable factor is the "health and nutritious value of food". The time conserved and the convenience in the preparation of food is one of the lifestyle factors that affect more than half of the students. The cost of the food was also found to have an effect. Among the third group of factors categorized as "media", the leading factor is advertisement, effective in one third of the students. Among boys and girls, there was no statistical difference in the type of meal skipped. Living in Izmir for more than 10 years compared to less than ten years, being in a nuclear family to extended family, and belonging to the "owner" social class to "wage laborer" class also do not statistically differ with regard to skipping meals. However, the mother's and father's education level and having a working mother are associated with skipping meals. These results provide important evidence to support opportunities to positively influence the adoption of healthful eating.

Rope skipping increases bone mineral density at calcanei of pubertal girls in Hong Kong: A quasi-experimental investigation.

Directory of Open Access Journals (Sweden)

Amy S Ha

Full Text Available Bone mineral accrual during puberty is important, especially in girls, because it is related to reduced risks of osteoporosis in adulthood. Previous research has shown that jumping or plyometric exercises may be effective in increasing bone mineral density in adolescents. Rope skipping is a form of activity that involves jumping, thus regular skipping may also increase bone mineral density in pubertal girls. To this end, we conducted a quasi-experimental to examine the effects of rope skipping on girls' bone mineral density and cardiovascular fitness. 176 Hong Kong girls (age = 12.23 ± 1.80 years at baseline were recruited to take part in the study. Bone density at their forearms and calcanei were measured twice over two academic years (mean time between visits was 10.3 months. Using multilevel modeling analyses and adjusting for participants' height and physical activity, we found that girls who participated in weekly rope skipping activities, compared to those who did not, had higher levels of bone density at the calcanei (B = 0.023, p < .01. However, no differences were found for bone density at forearms or participants' cardiovascular fitness. The rates of change of these variables across time were also not significantly different. Results suggest that regular rope skipping may increase girls' bone density at the lower extremities, irrespective of the amount of self-report physical activity. However, further research is required to examine the potential dose-response relation between skipping behaviors and the measured outcomes.

Injustice in Access to Health Information: The Difference between Health Professionals and Patients

Directory of Open Access Journals (Sweden)

Hasan Ashrafi-rizi

2016-10-01

Full Text Available The role of information is undeniable in promoting public health (1-3. “Access to health information for all” was the slogan of the World Health Organization in 2004 (4. The proving of this slogan requires access to health information by beneficiaries (health professionals and patients. Access to health information by specialists as partly been achieved, but access to health information for patients and their families is considered low (5-7, which could have adverse effects. Health professionals have quick and easy access to information through libraries and medical information centers, participation in seminars, exchange of scientific information with other professionals, as well as identifying ways to effectively access to health information, but patients and their families do not have access to such facilities and capabilities. Therefore, patients and their families are faced with a phenomenon known as “inequity in access to health information” and the continuation of the injustice leads to health information poverty. Thus, the main question now is what we should do? It seems that the government needs to develop a national policy in the field of health information and it is the most important step. In the next step, the government should expand the concept production via using potentials of different organizations like public media (TV and Radio, health ministry and press and increase the access of patients to health information in the easy language (level of health information between health professionals and patients is different.

Skipping Syntactically Illegal "the" Previews: The Role of Predictability

Science.gov (United States)

Abbott, Matthew J.; Angele, Bernhard; Ahn, Y. Danbi; Rayner, Keith

2015-01-01

Readers tend to skip words, particularly when they are short, frequent, or predictable. Angele and Rayner (2013) recently reported that readers are often unable to detect syntactic anomalies in parafoveal vision. In the present study, we manipulated target word predictability to assess whether contextual constraint modulates…

Dynamics of Leading-strand Lesion Skipping by the Replisome

Science.gov (United States)

Yeeles, Joseph T.P.; Marians, Kenneth J.

2013-01-01

SUMMARY The E. coli replisome stalls transiently when it encounters a lesion in the leading-strand template, skipping over the damage by reinitiating replication at a new primer synthesized downstream by the primase. We report here that template unwinding and lagging-strand synthesis continue downstream of the lesion at a reduced rate after replisome stalling, that one replisome is capable of skipping multiple lesions, and that the rate limiting steps of replication restart involve the synthesis and activation of the new primer downstream. We also find little support for the concept that polymerase uncoupling, where extensive lagging-strand synthesis proceeds downstream in the absence of leading-strand synthesis, involves physical separation of the leading-strand polymerase from the replisome. Instead, our data indicate that extensive uncoupled replication likely results from a failure of the leading-strand polymerase still associated with the DNA helicase and the lagging-strand polymerase that are proceeding downstream to reinitiate synthesis. PMID:24268579

Skipping meals and alcohol consumption. The regulation of energy intake and expenditure among weight loss participants.

Science.gov (United States)

Carels, Robert A; Young, Kathleen M; Coit, Carissa; Clayton, Anna Marie; Spencer, Alexis; Wagner, Marissa

2008-11-01

Research suggests that specific eating patterns (e.g., eating breakfast) may be related to favorable weight status. This investigation examined the relationship between eating patterns (i.e., skipping meals; consuming alcohol) and weight loss treatment outcomes (weight loss, energy intake, energy expenditure, and duration of exercise). Fifty-four overweight or obese adults (BMI> or =27 kg/m(2)) participated in a self-help or therapist-assisted weight loss program. Daily energy intake from breakfast, lunch, dinner, and alcoholic beverages, total daily energy intake, total daily energy expenditure, physical activity, and weekly weight loss were assessed. On days that breakfast or dinner was skipped, or alcoholic beverages were not consumed, less total daily energy was consumed compared to days that breakfast, dinner, or alcoholic beverages were consumed. On days that breakfast or alcohol was consumed, daily energy expenditure (breakfast only) and duration of exercise were higher compared to days that breakfast or alcohol was not consumed. Individuals who skipped dinner or lunch more often had lower energy expenditure and exercise duration than individuals who skipped dinner or lunch less often. Individuals who consumed alcohol more often had high daily energy expenditure than individuals who consumed alcohol less often. Skipping meals or consuming alcoholic beverages was not associated with weekly weight loss. In this investigation, weight loss program participants may have compensated for excess energy intake from alcoholic beverages and meals with greater daily energy expenditure and longer exercise duration.

Equal Access Initiative HIV/AIDS Information Resources from NLM

Energy Technology Data Exchange (ETDEWEB)

Templin-Branner W. and N. Dancy

2010-09-11

The Equal Access Initiative: HIV/AIDS Information Resources from the National Library of Medicine training is designed specifically for the National Minority AIDS Council 2010 Equal Access Initiative (EAI) Computer Grants Program awardees to provide valuable health information resources from the National Library of Medicine and other reliable sources to increase awareness of the wealth of treatment information and educational materials that are available on the Internet and to improve prevention and treatment education for their clients. These resources will also meet the needs of community-based

39 CFR 230.2 - Access to information and other responsibilities.

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Access to information and other responsibilities. 230.2 Section 230.2 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION OFFICE OF INSPECTOR GENERAL General Policy and Authority § 230.2 Access to information and other...

Evaluation of 2’-Deoxy-2’-fluoro Antisense Oligonucleotides for Exon Skipping in Duchenne Muscular Dystrophy

Directory of Open Access Journals (Sweden)

Silvana M G Jirka

2015-01-01

Full Text Available Duchenne muscular dystrophy (DMD is a severe muscle wasting disorder typically caused by frame-shifting mutations in the DMD gene. Restoration of the reading frame would allow the production of a shorter but partly functional dystrophin protein as seen in Becker muscular dystrophy patients. This can be achieved with antisense oligonucleotides (AONs that induce skipping of specific exons during pre-mRNA splicing. Different chemical modifications have been developed to improve AON properties. The 2’-deoxy-2’-fluoro (2F RNA modification is attractive for exon skipping due to its ability to recruit ILF2/3 proteins to the 2F/pre-mRNA duplex, which resulted in enhanced exon skipping in spinal muscular atrophy models. In this study, we examined the effect of two different 2’-substituted AONs (2’-F phosphorothioate (2FPS and 2’-O-Me phosphorothioate (2OMePS on exon skipping in DMD cell and animal models. In human cell cultures, 2FPS AONs showed higher exon skipping levels than their isosequential 2OMePS counterparts. Interestingly, in the mdx mouse model, 2FPS was less efficient than 2OMePS and suggested safety issues as evidenced by increased spleen size and weight loss. Our results do not support a clinical application for 2FPS AON.

Outlier Detection in Regression Using an Iterated One-Step Approximation to the Huber-Skip Estimator

DEFF Research Database (Denmark)

Johansen, Søren; Nielsen, Bent

2013-01-01

In regression we can delete outliers based upon a preliminary estimator and reestimate the parameters by least squares based upon the retained observations. We study the properties of an iteratively defined sequence of estimators based on this idea. We relate the sequence to the Huber-skip estima......In regression we can delete outliers based upon a preliminary estimator and reestimate the parameters by least squares based upon the retained observations. We study the properties of an iteratively defined sequence of estimators based on this idea. We relate the sequence to the Huber...... that the normalized estimation errors are tight and are close to a linear function of the kernel, thus providing a stochastic expansion of the estimators, which is the same as for the Huber-skip. This implies that the iterated estimator is a close approximation of the Huber-skip...

Administrative Transparency and the Access to Information

Directory of Open Access Journals (Sweden)

Luís Paulo Petersen Andreazza

2015-12-01

Full Text Available This article discusses the various forms and application ranges of the State secret throughout history, from its origins in classical political culture, to the evanescence of its intensity, when the right to information and the principles of good administration, advertising, transparency and democracy gain strength. In this scenario, in Brazil, the constitutional principle of transparency is highlighted, which transforms the notion of advertising, being no longer just an administrator option, to demand a public space in which the free movement of ideas and information starts to have potential to influence the scope and the action strategies of the State, providing certainty to State conducts and security to the administered. In the wake of this principle, comes the Access to Information Act, in order to print effectiveness in access to  administrative  information,  producing  intense  practical  effects  to  the  legal  and administrative relationship established between the Public Administration and administered and subjecting the power to control people, presenting a notorious identity with democracy. However, some points of this law provoked discussions regarding the possible conflict between individual and collective fundamental rights, as well as between the constitutional principles of transparency and publicity with the intimacy and privacy, as well as any collision with the infra-constitutional norms derived from the latter, as the confidentiality of financial data, bank secrecy and tax secrecy. The intention presented in this study is to establish the ownership of the reach of the Access to Information Act before the particular issue of disclosure in nominal compensation of state agents.

Availability of and ease of access to calorie information on restaurant websites.

Directory of Open Access Journals (Sweden)

Gary G Bennett

Full Text Available Offering calories on restaurant websites might be particularly important for consumer meal planning, but the availability of and ease of accessing this information are unknown.We assessed websites for the top 100 U.S. chain restaurants to determine the availability of and ease of access to calorie information as well as website design characteristics. We also examined potential predictors of calorie availability and ease of access.Eighty-two percent of restaurants provided calorie information on their websites; 25% presented calories on a mobile-formatted website. On average, calories could be accessed in 2.35±0.99 clicks. About half of sites (51.2% linked to calorie information via the homepage. Fewer than half had a separate section identifying healthful options (46.3%, or utilized interactive meal planning tools (35.4%. Quick service/fast casual, larger restaurants, and those with less expensive entrées and lower revenue were more likely to make calorie information available. There were no predictors of ease of access.Calorie information is both available and largely accessible on the websites of America's leading restaurants. It is unclear whether consumer behavior is affected by the variability in the presentation of calorie information.

Availability of and ease of access to calorie information on restaurant websites.

Science.gov (United States)

Bennett, Gary G; Steinberg, Dori M; Lanpher, Michele G; Askew, Sandy; Lane, Ilana B; Levine, Erica L; Goodman, Melody S; Foley, Perry B

2013-01-01

Offering calories on restaurant websites might be particularly important for consumer meal planning, but the availability of and ease of accessing this information are unknown. We assessed websites for the top 100 U.S. chain restaurants to determine the availability of and ease of access to calorie information as well as website design characteristics. We also examined potential predictors of calorie availability and ease of access. Eighty-two percent of restaurants provided calorie information on their websites; 25% presented calories on a mobile-formatted website. On average, calories could be accessed in 2.35±0.99 clicks. About half of sites (51.2%) linked to calorie information via the homepage. Fewer than half had a separate section identifying healthful options (46.3%), or utilized interactive meal planning tools (35.4%). Quick service/fast casual, larger restaurants, and those with less expensive entrées and lower revenue were more likely to make calorie information available. There were no predictors of ease of access. Calorie information is both available and largely accessible on the websites of America's leading restaurants. It is unclear whether consumer behavior is affected by the variability in the presentation of calorie information.

78 FR 31769 - Accessible Emergency Information; Apparatus Requirements for Emergency Information and Video...

Science.gov (United States)

2013-05-24

... and equipment and better access video programming.'' \\7\\ \\7\\ H.R. Rep. No. 111-563, 111th Cong., 2d... Video Accessibility Act of 2010 (``CVAA''), the Commission adopts rules requiring video programming distributors and video programming providers (including program owners) to make televised emergency information...

34 CFR 395.12 - Access to program and financial information.

Science.gov (United States)

2010-07-01

... 34 Education 2 2010-07-01 2010-07-01 false Access to program and financial information. 395.12... information. Each blind vendor under this part shall be provided access to all financial data of the State... annual financial reports, provided that such disclosure does not violate applicable Federal or State laws...

Targeted Exon Skipping to Correct Exon Duplications in the Dystrophin Gene

Directory of Open Access Journals (Sweden)

Kane L Greer

2014-01-01

Full Text Available Duchenne muscular dystrophy is a severe muscle-wasting disease caused by mutations in the dystrophin gene that ablate functional protein expression. Although exonic deletions are the most common Duchenne muscular dystrophy lesion, duplications account for 10–15% of reported disease-causing mutations, and exon 2 is the most commonly duplicated exon. Here, we describe the in vitro evaluation of phosphorodiamidate morpholino oligomers coupled to a cell-penetrating peptide and 2′-O-methyl phosphorothioate oligonucleotides, using three distinct strategies to reframe the dystrophin transcript in patient cells carrying an exon 2 duplication. Differences in exon-skipping efficiencies in vitro were observed between oligomer analogues of the same sequence, with the phosphorodiamidate morpholino oligomer coupled to a cell-penetrating peptide proving the most effective. Differences in exon 2 excision efficiency between normal and exon 2 duplication cells, were apparent, indicating that exon context influences oligomer-induced splice switching. Skipping of a single copy of exon 2 was induced in the cells carrying an exon 2 duplication, the simplest strategy to restore the reading frame and generate a normal dystrophin transcript. In contrast, multiexon skipping of exons 2–7 to generate a Becker muscular dystrophy-like dystrophin transcript was more challenging and could only be induced efficiently with the phosphorodiamidate morpholino oligomer chemistry.

Television viewing, computer game play and book reading during meals are predictors of meal skipping in a cross-sectional sample of 12-, 14- and 16-year-olds.

Science.gov (United States)

Custers, Kathleen; Van den Bulck, Jan

2010-04-01

To examine whether television viewing, computer game playing or book reading during meals predicts meal skipping with the aim of watching television, playing computer games or reading books (media meal skipping). A cross-sectional study was conducted using a standardized self-administered questionnaire. Analyses were controlled for age, gender and BMI. Data were obtained from a random sample of adolescents in Flanders, Belgium. Seven hundred and ten participants aged 12, 14 and 16 years. Of the participants, 11.8 % skipped meals to watch television, 10.5 % skipped meals to play computer games and 8.2 % skipped meals to read books. Compared with those who did not use these media during meals, the risk of skipping meals in order to watch television was significantly higher for those children who watched television during meals (2.9 times higher in those who watched television during at least one meal a day). The risk of skipping meals for computer game playing was 9.5 times higher in those who played computer games weekly or more while eating, and the risk of meal skipping in order to read books was 22.9 times higher in those who read books during meals less than weekly. The more meals the respondents ate with the entire family, the less likely they were to skip meals to watch television. The use of media during meals predicts meal skipping for using that same medium. Family meals appear to be inversely related to meal skipping for television viewing.

Research Investigation of Information Access Methods

Science.gov (United States)

Heinrichs, John H.; Sharkey, Thomas W.; Lim, Jeen-Su

2006-01-01

This study investigates the satisfaction of library users at Wayne State University who utilize alternative information access methods. The LibQUAL+[TM] desired and perceived that satisfaction ratings are used to determine the user's "superiority gap." By focusing limited library resources to address "superiority gap" issues identified by each…

Information Access Skills in Mothers as Containment of Internet Negative Impact

Directory of Open Access Journals (Sweden)

Putri Limilia

2018-02-01

Full Text Available Media and Information Literacy (MIL skills was one of the skills that must be possessed by netizens. These skills become important in the effort of coping with the negative impact of the internet. The high penetration of the internet is not followed by the high skill of MIL. Therefore, the writers are interested to know the skills of information and media literacy (access skills in mothers. This study uses descriptive quantitative method by using questionnaires as means of data collection. The result of the study shows that mothers tend to have moderate-level information access skills. The skills are reflected in the skills of mothers at moderate level in understanding the role of information, seeking sources of information, accessing information effectively and efficiently, and storing information.

Access and control of information and intellectual property

Science.gov (United States)

Lang, Gerald S.

1996-03-01

This paper introduces the technology of two pioneering patents for the secure distribution of information and intellectual property. The seminal technology has been used in the control of sensitive material such as medical records and imagery in distributed networks. It lends itself to the implementation of an open architecture access control system that provides local or remote user selective access to digital information stored on any computer system or storage medium, down to the data element, pixel, and sub-pixel levels. Use of this technology is especially suited for electronic publishing, health care records, MIS, and auditing.

Access to the Information Superhighway and Emerging Information Technologies by People with Disabilities.

Science.gov (United States)

National Council on Disability, Washington, DC.

This report discusses the growth of the National Information Infrastructure (NII), or the information superhighway, and its implications for people with disabilities. Advantages for people with disabilities include: increasing the ability of individuals with some types of disabilities to access and use information; decreasing personal isolation…

Targeted Exon Skipping to Address “Leaky” Mutations in the Dystrophin Gene

Directory of Open Access Journals (Sweden)

Sue Fletcher

2012-01-01

Full Text Available Protein-truncating mutations in the dystrophin gene lead to the progressive muscle wasting disorder Duchenne muscular dystrophy, whereas in-frame deletions typically manifest as the milder allelic condition, Becker muscular dystrophy. Antisense oligomer-induced exon skipping can modify dystrophin gene expression so that a disease-associated dystrophin pre-mRNA is processed into a Becker muscular dystrophy-like mature transcript. Despite genomic deletions that may encompass hundreds of kilobases of the gene, some dystrophin mutations appear “leaky”, and low levels of high molecular weight, and presumably semi-functional, dystrophin are produced. A likely causative mechanism is endogenous exon skipping, and Duchenne individuals with higher baseline levels of dystrophin may respond more efficiently to the administration of splice-switching antisense oligomers. We optimized excision of exons 8 and 9 in normal human myoblasts, and evaluated several oligomers in cells from eight Duchenne muscular dystrophy patients with deletions in a known “leaky” region of the dystrophin gene. Inter-patient variation in response to antisense oligomer induced skipping in vitro appeared minimal. We describe oligomers targeting exon 8, that unequivocally increase dystrophin above baseline in vitro, and propose that patients with leaky mutations are ideally suited for participation in antisense oligomer mediated splice-switching clinical studies.

The relation between breakfast skipping and school performance in adolescents

NARCIS (Netherlands)

Boschloo, Annemarie; Ouwehand, Carolijn; Dekker, Sanne; Lee, Nikki; De Groot, Renate; Krabbendam, Lydia; Jolles, Jelle

2012-01-01

Boschloo, A., Ouwehand, C., Dekker, S., Lee, N., De Groot, R., Krabbendam, L., & Jolles, J. (2012). The relation between breakfast skipping and school performance in adolescents. Mind, Brain, and Education, 6(2), 81-88. doi:10.1111/j.1751-228x.2012.01138.x

Antisense mediated exon skipping therapy for duchenne muscular dystrophy (DMD)

DEFF Research Database (Denmark)

Brolin, Camilla; Shiraishi, Takehiko

2011-01-01

Duchenne Muscular Dystrophy (DMD) is a lethal disease caused by mutations in the dystrophin gene (DMD) that result in the absence of essential muscle protein dystrophin. Among many different approaches for DMD treatment, exon skipping, mediated by antisense oligonucleotides, is one of the most...

An observational study of consumers' accessing of nutrition information in chain restaurants.

Science.gov (United States)

Roberto, Christina A; Agnew, Henry; Brownell, Kelly D

2009-05-01

In this observational study, we determined how frequently consumers accessed on-premises nutrition information provided at chain restaurants. The number of patrons entering and accessing nutrition information was recorded at 8 locations that were part of 4 major restaurant chains (McDonald's, Burger King, Starbucks, and Au Bon Pain). Only 6 (0.1%) of 4311 patrons accessed on-premises nutrition information before purchasing food. This very small percentage suggests that such information should be more prominently displayed, such as on restaurant menu boards, to help customers make informed decisions.

An Observational Study of Consumers’ Accessing of Nutrition Information in Chain Restaurants

Science.gov (United States)

Agnew, Henry; Brownell, Kelly D.

2009-01-01

In this observational study, we determined how frequently consumers accessed on-premises nutrition information provided at chain restaurants. The number of patrons entering and accessing nutrition information was recorded at 8 locations that were part of 4 major restaurant chains (McDonald's, Burger King, Starbucks, and Au Bon Pain). Only 6 (0.1%) of 4311 patrons accessed on-premises nutrition information before purchasing food. This very small percentage suggests that such information should be more prominently displayed, such as on restaurant menu boards, to help customers make informed decisions. PMID:19299679

40 CFR 61.243-2 - Alternative standards for valves in VHAP service-skip period leak detection and repair.

Science.gov (United States)

2010-07-01

... VHAP service-skip period leak detection and repair. 61.243-2 Section 61.243-2 Protection of Environment... AIR POLLUTANTS National Emission Standard for Equipment Leaks (Fugitive Emission Sources) § 61.243-2 Alternative standards for valves in VHAP service—skip period leak detection and repair. (a)(1) An owner or...

Electronic Information Access and Utilization by Makerere University Students in Uganda

Directory of Open Access Journals (Sweden)

Elisam Magara

2008-09-01

Full Text Available Objectives – The objectives of this study were to establish the level of computer utilization skills of Makerere University (Uganda Library and Information Science (LIS students; to determine the use of electronic information resources by LIS students; to determine the attitudes of LIS students towards electronic information resources; and to establish the problems faced by LIS students in accessing electronic information resources.Methods – A questionnaire survey was used for data collection.Results – The majority of Library and Information Science students at Makerere University depend on university computers for their work, and very few of them access the library’s e-resources. The few who access e-resources are self-taught. The majority of students surveyed were unaware of Emerald and EBSCO databases relevant to Library and Information Science students, and they found accessing eresources time-consuming. Conclusion – The study concluded that a concerted effort is needed by both LIS lecturers and university librarians in promoting use of the library’s electronic resources.

Public access of environmental information. Report of an Interdepartmental Working Party on public access to information held by Pollution Control Authorities

International Nuclear Information System (INIS)

1986-01-01

The working party was set up to report to the Government ways of implementing the recommendations of the Royal Commission on Environmental Pollution that 'there should be a presumption in favour of unrestricted public access to the information which the pollution control authorities obtain or receive by virtue of their statutory powers'. Chapter 6 deals with Radioactive wastes. The present situation (eg on how the information is gathered, which department or bodies are involved etc) and the current state of the law are discussed. Licensed nuclear sites, sea disposal, inspections and defence wastes are all considered briefly. The case for improving public access to information and, recommendations on how to achieve this made, and the resource implications considered. On control of radioactive wastes there is currently no power for the responsible Government Departments to make information public. It is recommended that new legislation should confer powers to make information available, including a power to require public registers to be kept at prescribed places giving information related to certificates issued under the Radioactive Substances Act 1960. (UK)

Zen meditation and access to information in the unconscious

NARCIS (Netherlands)

Strick, M.A.; Noorden, T.H.J. van; Ritskes, R.R.; Ruiter, J.R. de; Dijksterhuis, A.J.

2012-01-01

In two experiments and two different research paradigms, we tested the hypothesis that Zen meditation increases access to accessible but unconscious information. Zen practitioners who meditated in the lab performed better on the Remote Associate Test (RAT; Mednick, 1962) than Zen practitioners who

Probabilistic models for access strategies to dynamic information elements

DEFF Research Database (Denmark)

Hansen, Martin Bøgsted; Olsen, Rasmus L.; Schwefel, Hans-Peter

In various network services (e.g., routing and instances of context-sensitive networking) remote access to dynamically changing information elements is a required functionality. Three fundamentally different strategies for such access are investigated in this paper: (1) a reactive approach...... initiated by the requesting entity, and two versions of proactive approaches in which the entity that contains the information element actively propagates its changes to potential requesters, either (2) periodically or (3) triggered by changes of the information element. This paper develops probabilistic...... for information elements spread over a large number of network nodes are provided, which allow to draw conclusions on scalability properties. The impact of different distribution types for the network delays as well as for the time between changes of the information element on the mismatch probability...

Public Access to Government Electronic Information. Policy Framework.

Science.gov (United States)

Bulletin of the American Society for Information Science, 1992

1992-01-01

This policy framework provides guidelines for federal agencies on public access to government electronic information. Highlights include reasons for disseminating information; defining user groups; which technology to use; pricing flexibility; security and privacy issues; and the private sector and state and local government roles. (LRW)

Phases and Steps in the Access to Data in Information Tools

DEFF Research Database (Denmark)

Bergenholtz, Henning; Bothma, Theo; Gouws, Rufus

2015-01-01

route and access time, but not access structure. This term is not only ill defined – it is less relevant, because each user has different access routes, and also the same user makes use of different routes in different cases. We describe four experiments in a case study with one test person how...... the different access processes in different user situations take place. This test person is trying to solve different accounting information needs in different user situations. The aim of this paper is to compare and contrast the access process terminology of lexicography and information science, to systematize...... the terms in a logical structure and to show how these disciplines complement one another by providing clearer definitions to describe the different access processes....

Breakfast-skipping in children and young adolescents in the Netherlands

NARCIS (Netherlands)

Brugman, E.; Meulmeester, J.F.; Spee-Wekke, A. van der; Verloove-Vanhorick, S.P.

1998-01-01

Background: The objective of this study was to provide national figures on the prevalence of breakfast-skipping and the association with sociodemographic variables in 4-15 year old children. Methods: Data of 4,377 children were collected. A food questionnaire (24 h recall) was completed by the

47 CFR 54.621 - Access to advanced telecommunications and information services.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 3 2010-10-01 2010-10-01 false Access to advanced telecommunications and information services. 54.621 Section 54.621 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED... § 54.621 Access to advanced telecommunications and information services. (a) Twenty-five percent of the...

Improving information access by relevance and topical feedback

NARCIS (Netherlands)

Kaptein, R.; Kamps, J.; Hopfgartner, F.

2008-01-01

One of the main bottle-necks in providing more effective information access is the poverty of the query end. With an average query length of about two terms, users provide only a highly ambiguous statement of the, often complex, underlying information need. Implicit and explicit feedback can provide

Students' access usage and awareness of electronic information ...

African Journals Online (AJOL)

Students' access usage and awareness of electronic information resources at the University College Hospital, University of Ibadan, Nigeria. RA Ojo, SO Akande. Abstract. No Abstract. Lagos Journal of Library and Information Science Vol. 3(1) 2005: 16-24. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD ...

MULTIPLE ACCESS POINTS WITHIN THE ONLINE CLASSROOM: WHERE STUDENTS LOOK FOR INFORMATION

Directory of Open Access Journals (Sweden)

John STEELE

2017-01-01

Full Text Available The purpose of this study is to examine the impact of information placement within the confines of the online classroom architecture. Also reviewed was the impact of other variables such as course design, teaching presence and student patterns in looking for information. The sample population included students from a major online university in their first year course sequence. Students were tasked with completing a survey at the end of the course, indicating their preference for accessing information within the online classroom. The qualitative data indicated that student preference is to receive information from multiple access points and sources within the online classroom architecture. Students also expressed a desire to have information delivered through the usage of technology such as email and text messaging. In addition to receiving information from multiple sources, the qualitative data indicated students were satisfied overall, with the current ways in which they received and accessed information within the online classroom setting. Major findings suggest that instructors teaching within the online classroom should have multiple data access points within the classroom architecture. Furthermore, instructors should use a variety of communication venues to enhance the ability for students to access and receive information pertinent to the course.

Information system architecture to support transparent access to distributed, heterogeneous data sources

International Nuclear Information System (INIS)

Brown, J.C.

1994-08-01

Quality situation assessment and decision making require access to multiple sources of data and information. Insufficient accessibility to data exists for many large corporations and Government agencies. By utilizing current advances in computer technology, today's situation analyst's have a wealth of information at their disposal. There are many potential solutions to the information accessibility problem using today's technology. The United States Department of Energy (US-DOE) faced this problem when dealing with one class of problem in the US. The result of their efforts has been the creation of the Tank Waste Information Network System -- TWINS. The TWINS solution combines many technologies to address problems in several areas such as User Interfaces, Transparent Access to Multiple Data Sources, and Integrated Data Access. Data related to the complex is currently distributed throughout several US-DOE installations. Over time, each installation has adopted their own set of standards as related to information management. Heterogeneous hardware and software platforms exist both across the complex and within a single installation. Standards for information management vary between US-DOE mission areas within installations. These factors contribute to the complexity of accessing information in a manner that enhances the performance and decision making process of the analysts. This paper presents one approach taken by the DOE to resolve the problem of distributed, heterogeneous, multi-media information management for the HLW Tank complex. The information system architecture developed for the DOE by the TWINS effort is one that is adaptable to other problem domains and uses

The information divide: publishing and access issues | Baker ...

African Journals Online (AJOL)

Changes in information access are explored at a macro-environment (global), and then a micro-environment (local) level. It is argued that changes in the publishing industry have occurred not only because of the advent of electronic publishing, but also because of a fundamental paradigm shift from \\"information as societal ...

Citizen and the press : access to public information

NARCIS (Netherlands)

den Boef, August Hans; Kircz, Joost; Riekert, Wolf-Fritz; Simon, Ingeborg

2012-01-01

The essence of a democratic process is the guarantee that citizens have free and easy access to public information. How can that be made possible and how can people learn to use that information critically? In earlier papers (Boef, et.al. 2008 and 2009), we discussed the relationship between public

An Unequal Information Society: How Information Access Initiatives Contribute to the Construction of Inequality

Science.gov (United States)

Sanfilippo, Madelyn Rose

2016-01-01

Unequal access to information has significant social and political consequences, and is itself a consequence of sociotechnical systems born of social, cultural, economic, and institutional context. Information is unequally distributed both within and between communities. While many factors that shape information inequality shift subtly over time,…

Determinants of Access and Farmers' use of Information and ...

African Journals Online (AJOL)

This poor farmers access to and use of new ICTs can limit the extent of agricultural information they can receive. The probability of respondents having high access to new ICTS was significantly related to education (b = 0.784) and farming income, (b = 0.754). The study recommends organizing farmers into associations for ...

Skip cycle system for spark ignition engines: An experimental investigation of a new type working strategy

International Nuclear Information System (INIS)

Kutlar, Osman Akin; Arslan, Hikmet; Calik, Alper T.

2007-01-01

A new type working strategy for spark ignition engine, named skip cycle, is examined. The main idea is to reduce the effective stroke volume of an engine by cutting off fuel injection and spark ignition in some of the classical four stroke cycles. When the cycle is skipped, additionally, a rotary valve is used in the intake to reduce pumping losses in part load conditions. The effect of this strategy is similar to that of variable displacement engines. Alternative power stroke fractions in one cycle and applicability in single cylinder engines are specific advantageous properties of the proposed system. A thermodynamic model, besides experimental results, is used to explain the skip cycle strategy in more detail. This theoretical investigation shows considerable potential to increase the efficiency at part load conditions. Experimental results obtained with this novel strategy show that the throttle valve of the engine opens wider and the minimum spark advance for maximum brake torque decreases in comparison to those of the classical operation system. The brake specific fuel consumption decreases at very low speed and load, while it increases at higher speed and load due to the increased fuel loss within the skipped cycles. In this working mode, the engine operates at lower idle speed without any stability problem; and moreover with less fuel consumption

An end-to-end secure patient information access card system.

Science.gov (United States)

Alkhateeb, A; Singer, H; Yakami, M; Takahashi, T

2000-03-01

The rapid development of the Internet and the increasing interest in Internet-based solutions has promoted the idea of creating Internet-based health information applications. This will force a change in the role of IC cards in healthcare card systems from a data carrier to an access key medium. At the Medical Informatics Department of Kyoto University Hospital we are developing a smart card patient information project where patient databases are accessed via the Internet. Strong end-to-end data encryption is performed via Secure Socket Layers, transparent to transmit patient information. The smart card is playing the crucial role of access key to the database: user authentication is performed internally without ever revealing the actual key. For easy acceptance by healthcare professionals, the user interface is integrated as a plug-in for two familiar Web browsers, Netscape Navigator and MS Internet Explorer.

Access to flexible working and informal care

OpenAIRE

Bryan, Mark L.

2011-01-01

We use matched employer-employee data to explore the relationship between employees' access to flexible working arrangements and the amount of informal care they provide to sick or elderly friends and relatives. Flexitime and the ability to reduce working hours are each associated with about 10% more hours of informal care, with effects concentrated among full-time workers providing small amounts of care. The wider workplace environment beyond formal flexible work also appears to facilitate c...

User Management with LDAP(Light weight Directory Access Protocolfor access to technology and Information Services in Companies

Directory of Open Access Journals (Sweden)

José Teodoro Mejía Viteri

2016-08-01

Full Text Available This research aims to conduct an analysis of management services information and users with LDAP (Lightweight / Simplified Directory Access Protocol, their interaction with other technology services company, allowing it to be accessed through a single user and password. This study allowed us to collect information through a literature review on the LDAP service and its ability to interact with your user directory Open source technology services; also with Windows Server and Active Directory service is used by companies for their ease of management and access resources on Windows clients; is intended to provide an alternative for the implementation of each of the services required by public and private companies with tools free use and access to services for management and administration can be done by integrating or synchronizing with the directory LDAP.

Perspectives on access to personal health information in New Zealand/Aotearoa.

Science.gov (United States)

Menkes, David B; Hill, Charlotte J; Horsfall, Melissa; Jaye, Chrystal

2008-12-01

This study used group interviews to explore Māori and European New Zealander (Pakeha) perspectives on access to personal health information. Two predominant themes emerged: the tension between the individual and society, and differences inherent in the use of formal and informal moral codes. Māori and Pakeha differed in their concept of autonomy and relied on distinct moral codes when considering questions of access; Western values and moral codes were notably less relevant to Māori who described distinct, collectivist means of ensuring social care of the sick and dying. Pakeha but not Māori participants often used hypothetical situations to reach an abstract determination of 'who should know'; the latter instead used personal experience to decide case-by-case. Generational differences were also evident, particularly in the Māori groups. In conclusion, culture should be considered in access to personal health information in New Zealand. Similar cultural variation is likely to be found in other countries; recognition of such differences will help ensure that access to sensitive information is appropriate, inclusive, and ethical.

An application-layer based centralized information access control for VPN

Institute of Scientific and Technical Information of China (English)

OUYANG Kai; ZHOU Jing-li; XIA Tao; YU Sheng-sheng

2006-01-01

With the rapid development of Virtual Private Network (VPN), many companies and organizations use VPN to implement their private communication. Traditionally, VPN uses security protocols to protect the confidentiality of data, the message integrity and the endpoint authentication. One core technique of VPN is tunneling, by which clients can access the internal servers traversing VPN. However, the tunneling technique also introduces a concealed security hole. It is possible that ifone vicious user can establish tunneling by the VPN server, he can compromise the internal servers behind the VPN server. So this paper presents a novel Application-layer based Centralized Information Access Control (ACIAC) for VPN to solve this problem.To implement an efficient, flexible and multi-decision access control model, we present two key techniques to ACIAC-the centralized management mechanism and the stream-based access control. Firstly, we implement the information center and the constraints/events center for ACIAC. By the two centers, we can provide an abstract access control mechanism, and the material access control can be decided dynamically by the ACIAC's constraint/event mechanism. Then we logically classify the VPN communication traffic into the access stream and the data stream so that we can tightly couple the features of VPN communication with the access control model. We also provide the design of our ACIAC prototype in this paper.

Need an Information Security in Access Control System?

Directory of Open Access Journals (Sweden)

V. R. Petrov

2011-12-01

Full Text Available The purpose of this paper is the general problems of information security in access control system. The field of using is the in project of reconstruction Physical protection system.

Skipping Posterior Dynamic Transpedicular Stabilization for Distant Segment Degenerative Disease

Directory of Open Access Journals (Sweden)

Bilgehan Solmaz

2012-01-01

Full Text Available Objective. To date, there is still no consensus on the treatment of spinal degenerative disease. Current surgical techniques to manage painful spinal disorders are imperfect. In this paper, we aimed to evaluate the prospective results of posterior transpedicular dynamic stabilization, a novel surgical approach that skips the segments that do not produce pain. This technique has been proven biomechanically and radiologically in spinal degenerative diseases. Methods. A prospective study of 18 patients averaging 54.94 years of age with distant spinal segment degenerative disease. Indications consisted of degenerative disc disease (57%, herniated nucleus pulposus (50%, spinal stenosis (14.28%, degenerative spondylolisthesis (14.28%, and foraminal stenosis (7.1%. The Oswestry Low-Back Pain Disability Questionnaire and visual analog scale (VAS for pain were recorded preoperatively and at the third and twelfth postoperative months. Results. Both the Oswestry and VAS scores showed significant improvement postoperatively (P<0.05. We observed complications in one patient who had spinal epidural hematoma. Conclusion. We recommend skipping posterior transpedicular dynamic stabilization for surgical treatment of distant segment spinal degenerative disease.

Facilitating consumer access to health information.

Science.gov (United States)

Snowdon, Anne; Schnarr, Karin; Alessi, Charles

2014-01-01

The lead paper from Zelmer and Hagens details the substantive evolution occurring in health information technologies that has the potential to transform the relationship between consumers, health practitioners and health systems. In this commentary, the authors suggest that Canada is experiencing a shift in consumer behaviour toward a desire to actively manage one's health and wellness that is being facilitated through the advent of health applications on mobile and online technologies platforms. The result is that Canadians are now able to create personalized health solutions based on their individual health values and goals. However, before Canadians are able to derive a personal health benefit from these rapid changes in information technology, they require and are increasingly demanding greater real-time access to their own health information to better inform decision-making, as well as interoperability between their personal health tracking systems and those of their health practitioner team.

Live-Cell Imaging Visualizes Frequent Mitotic Skipping During Senescence-Like Growth Arrest in Mammary Carcinoma Cells Exposed to Ionizing Radiation

Energy Technology Data Exchange (ETDEWEB)

Suzuki, Masatoshi, E-mail: msuzuki@nagasaki-u.ac.jp [Department of Radiation Medical Sciences, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki (Japan); Yamauchi, Motohiro; Oka, Yasuyoshi; Suzuki, Keiji; Yamashita, Shunichi [Department of Radiation Medical Sciences, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki (Japan)

2012-06-01

Purpose: Senescence-like growth arrest in human solid carcinomas is now recognized as the major outcome of radiotherapy. This study was designed to analyze cell cycle during the process of senescence-like growth arrest in mammary carcinoma cells exposed to X-rays. Methods and Materials: Fluorescent ubiquitination-based cell cycle indicators were introduced into the human mammary carcinoma cell line MCF-7. Cell cycle was sequentially monitored by live-cell imaging for up to 5 days after exposure to 10 Gy of X-rays. Results: Live-cell imaging revealed that cell cycle transition from G2 to G1 phase without mitosis, so-called mitotic skipping, was observed in 17.1% and 69.8% of G1- and G2-irradiated cells, respectively. Entry to G1 phase was confirmed by the nuclear accumulation of mKO{sub 2}-hCdt1 as well as cyclin E, which was inversely correlated to the accumulation of G2-specific markers such as mAG-hGeminin and CENP-F. More than 90% of cells skipping mitosis were persistently arrested in G1 phase and showed positive staining for the senescent biochemical marker, which is senescence-associated ss-galactosidase, indicating induction of senescence-like growth arrest accompanied by mitotic skipping. While G2 irradiation with higher doses of X-rays induced mitotic skipping in approximately 80% of cells, transduction of short hairpin RNA (shRNA) for p53 significantly suppressed mitotic skipping, suggesting that ionizing radiation-induced mitotic skipping is associated with p53 function. Conclusions: The present study found the pathway of senescence-like growth arrest in G1 phase without mitotic entry following G2-irradiation.

Live-Cell Imaging Visualizes Frequent Mitotic Skipping During Senescence-Like Growth Arrest in Mammary Carcinoma Cells Exposed to Ionizing Radiation

International Nuclear Information System (INIS)

Suzuki, Masatoshi; Yamauchi, Motohiro; Oka, Yasuyoshi; Suzuki, Keiji; Yamashita, Shunichi

2012-01-01

Purpose: Senescence-like growth arrest in human solid carcinomas is now recognized as the major outcome of radiotherapy. This study was designed to analyze cell cycle during the process of senescence-like growth arrest in mammary carcinoma cells exposed to X-rays. Methods and Materials: Fluorescent ubiquitination-based cell cycle indicators were introduced into the human mammary carcinoma cell line MCF-7. Cell cycle was sequentially monitored by live-cell imaging for up to 5 days after exposure to 10 Gy of X-rays. Results: Live-cell imaging revealed that cell cycle transition from G2 to G1 phase without mitosis, so-called mitotic skipping, was observed in 17.1% and 69.8% of G1- and G2-irradiated cells, respectively. Entry to G1 phase was confirmed by the nuclear accumulation of mKO 2 -hCdt1 as well as cyclin E, which was inversely correlated to the accumulation of G2-specific markers such as mAG-hGeminin and CENP-F. More than 90% of cells skipping mitosis were persistently arrested in G1 phase and showed positive staining for the senescent biochemical marker, which is senescence-associated ß-galactosidase, indicating induction of senescence-like growth arrest accompanied by mitotic skipping. While G2 irradiation with higher doses of X-rays induced mitotic skipping in approximately 80% of cells, transduction of short hairpin RNA (shRNA) for p53 significantly suppressed mitotic skipping, suggesting that ionizing radiation-induced mitotic skipping is associated with p53 function. Conclusions: The present study found the pathway of senescence-like growth arrest in G1 phase without mitotic entry following G2-irradiation.

Government records management and access to information ...

African Journals Online (AJOL)

This article provides a brief report on the proceedings of the 9th Annual Integrity Action Summer School's policy lab on Government Records Management and Citizen Access to Information, held in July 2013 at the Central European University, Hungary and attended by international experts in records management and ...

39 CFR 3050.53 - Information on customer satisfaction and retail access. [Reserved

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Information on customer satisfaction and retail access. [Reserved] 3050.53 Section 3050.53 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL PERIODIC REPORTING § 3050.53 Information on customer satisfaction and retail access. [Reserved] ...

Accessing wound-care information on the Internet: the implications for patients.

Science.gov (United States)

Bovill, E S; Hormbrey, E; Gillespie, P H; Banwell, P E

2001-02-01

The Internet and the World Wide Web have revolutionised communication and provide a unique forum for the exchange of information. It has been proposed that the Internet has given the public more access to medical information resources and improved patient education. This study assessed the impact of the Internet on the availability of information on wound care management. The search phrases 'wound care', 'wound healing' and 'wounds' were analysed using a powerful Metacrawler search engine (www.go2net.com). Web site access was classified according to the target audience (wound-care specialists, other health professionals, patients) and the author (societies, institutions or commercial companies). The largest proportion of web sites were commercially based (32%). Of the total number, 23% specifically targeted patients, mostly by advertising. Only 20% were aimed at wound specialists. Extensive surfing was required to obtain wound-care information, and objective information sites were under-represented. Regulated, easily accessible, objective information sites on wound-healing topics are needed for improved patient education and to balance the existing commercial bias.

Skipping Breakfast is Correlated with Obesity.

Science.gov (United States)

Watanabe, Yoko; Saito, Isao; Henmi, Ikuyo; Yoshimura, Kana; Maruyama, Kotatsu; Yamauchi, Kanako; Matsuo, Tatsuhiro; Kato, Tadahiro; Tanigawa, Takeshi; Kishida, Taro; Asada, Yasuhiko

2014-01-01

Despite the fact that the total energy intake of Japanese people has decreased, the percentage of obese people has increased. This suggests that the timing of meals is related to obesity. The purpose of the study was to investigate the relationship between the timing of meals and obesity, based on analyses of physical measurements, serum biochemical markers, nutrient intake, and lifestyle factors in the context of Chrononutrition. We analyzed data derived from 766 residents of Toon City (286 males and 480 females) aged 30 to 79 years who underwent detailed medical examinations between 2011 and 2013. These medical examinations included. (1) physical measurements (waist circumference, blood pressure, etc.); (2) serum biochemical markers (total cholesterol, etc.); (3) a detailed questionnaire concerning lifestyle factors such as family structure and daily habits (22 issues), exercise and eating habits (28 issues), alcohol intake and smoking habits; (4) a food frequency questionnaire based on food groups (FFQg); and (5) a questionnaire concerning the times at which meals and snacks are consumed. The values for body mass index (BMI) and waist circumference were higher for participants who ate dinner less than three hours before bedtime (3-h group). The Chi-square test showed that there was a significant difference in eating habits, e.g., eating snacks, eating snacks at night, having dinner after 8 p.m., and having dinner after 9 p.m., between the 3-h group. Multiple linear regression analysis showed that skipping breakfast significantly influenced both waist circumference (β = 5.271) and BMI (β = 1.440) and that eating dinner influenced BMI (β = 0.581). Skipping breakfast had a greater influence on both waist circumference and BMI than eating dinner <3-h before going to bed.

28 CFR 20.34 - Individual's right to access criminal history record information.