Konvergensi di Ruang Redaksi pada Kelompok Media Tempo

Directory of Open Access Journals (Sweden)

Wahyudi Marhaen Pratopo

2018-03-01

Full Text Available This study seeks to reveal the implementation of convergence in the newsroom with case study of Tempo Group. This research uses qualitative approach and case study method. This study reveals that Tempo began to implement newroom convergence after publishing Kora Tempo in 2001. The effort toward newsroom convergence was realized by forming Tempo Newsroom which is meant as a news control center. After passing a series of trials and policy changes, the Tempo Group finally adopted full editorial convergence since 2012. In the application of this editorial convergence, Tempo chose the Newsroom 3.0 model, a newsroom management system that brings together news gathering and news processing to provide news needs for some outlet: tempo.co, Koran Tempo, and Tempo Magazine.

Tropospheric Emissions: Monitoring of Pollution (TEMPO)

Science.gov (United States)

Chance, Kelly; Liu, Xiong; Suleiman, Raid M.; Flittner, David E.; Al-Saadi, Jassim; Janz, Scott J.

2014-06-01

TEMPO, selected by NASA as the first Earth Venture Instrument, will measure atmospheric pollution for greater North America from space using ultraviolet and visible spectroscopy. TEMPO measures from Mexico City to the Canadian oil sands, and from the Atlantic to the Pacific, hourly and at high spatial resolution. TEMPO provides a tropospheric measurement suite that includes the key elements of tropospheric air pollution chemistry. Measurements are from geostationary (GEO) orbit, to capture the inherent high variability in the diurnal cycle of emissions and chemistry. The small product spatial footprint resolves pollution sources at sub-urban scale. Together, this temporal and spatial resolution improves emission inventories, monitors population exposure, and enables effective emission-control strategies. TEMPO takes advantage of a GEO host spacecraft to provide a modest-cost mission that measures the spectra required to retrieve O3, NO2, SO2, H2CO, C2H2O2, H2O, aerosols, cloud parameters, and UVB radiation. TEMPO thus measures the major elements, directly or by proxy, in the tropospheric O3 chemistry cycle. Multi-spectral observations provide sensitivity to O3 in the lowermost troposphere, reducing uncertainty in air quality predictions by 50 %. TEMPO quantifies and tracks the evolution of aerosol loading. It provides near-real-time air quality products that will be made widely, publicly available. TEMPO makes the first tropospheric trace gas measurements from GEO, by building on the heritage of five spectrometers flown in low-earth-orbit (LEO). These LEO instruments measure the needed spectra, although at coarse spatial and temporal resolutions, to the precisions required for TEMPO and use retrieval algorithms developed for them by TEMPO Science Team members and currently running in operational environments. This makes TEMPO an innovative use of a well-proven technique, able to produce a revolutionary data set. TEMPO provides much of the atmospheric measurement

The Effect of Melodic Activity, Tempo Change, and Audible Beat on Tempo Perception of Elementary School Students.

Science.gov (United States)

Kuhn, Terry Lee; Booth, Gregory D.

1988-01-01

Investigated the influence of melodic activity (ornamented and plain) on students' perception of tempo. Third, fifth, and sixth graders indicated whether the tempo of the second example in each paired comparison item was faster, slower, or stayed the same. Suggests that tempo perception lessons be preceded by instruction on melodic activity and…

Sex, acceleration, brain imaging, and rhesus monkeys: Converging evidence for an evolutionary bias for looming auditory motion

Science.gov (United States)

Neuhoff, John G.

2003-04-01

Increasing acoustic intensity is a primary cue to looming auditory motion. Perceptual overestimation of increasing intensity could provide an evolutionary selective advantage by specifying that an approaching sound source is closer than actual, thus affording advanced warning and more time than expected to prepare for the arrival of the source. Here, multiple lines of converging evidence for this evolutionary hypothesis are presented. First, it is shown that intensity change specifying accelerating source approach changes in loudness more than equivalent intensity change specifying decelerating source approach. Second, consistent with evolutionary hunter-gatherer theories of sex-specific spatial abilities, it is shown that females have a significantly larger bias for rising intensity than males. Third, using functional magnetic resonance imaging in conjunction with approaching and receding auditory motion, it is shown that approaching sources preferentially activate a specific neural network responsible for attention allocation, motor planning, and translating perception into action. Finally, it is shown that rhesus monkeys also exhibit a rising intensity bias by orienting longer to looming tones than to receding tones. Together these results illustrate an adaptive perceptual bias that has evolved because it provides a selective advantage in processing looming acoustic sources. [Work supported by NSF and CDC.

Eco-evolutionary dynamics in a coevolving host-virus system.

Science.gov (United States)

Frickel, Jens; Sieber, Michael; Becks, Lutz

2016-04-01

Eco-evolutionary dynamics have been shown to be important for understanding population and community stability and their adaptive potential. However, coevolution in the framework of eco-evolutionary theory has not been addressed directly. Combining experiments with an algal host and its viral parasite, and mathematical model analyses we show eco-evolutionary dynamics in antagonistic coevolving populations. The interaction between antagonists initially resulted in arms race dynamics (ARD) with selective sweeps, causing oscillating host-virus population dynamics. However, ARD ended and populations stabilised after the evolution of a general resistant host, whereas a trade-off between host resistance and growth then maintained host diversity over time (trade-off driven dynamics). Most importantly, our study shows that the interaction between ecology and evolution had important consequences for the predictability of the mode and tempo of adaptive change and for the stability and adaptive potential of populations. © 2016 John Wiley & Sons Ltd/CNRS.

I misteri del tempo l'universo dopo Einstein

CERN Document Server

Davies, Paul

1996-01-01

Quando fu esattamente l'inizio del tempo? Il viaggio nel tempo è realtà o fantasia? Sono possibili gli esperimenti con il tempo? Questo importante saggio indaga sull'enigma del tempo, un tema affascinante da sempre al centro delle speculazioni scientifiche e religiose.

Characterization of TEMPO-oxidized bacterial cellulose; Caracterizacao de celulose bacteriana tempo-oxidada

Energy Technology Data Exchange (ETDEWEB)

Nascimento, Eligenes S.; Pereira, Andre L.S.; Lima, Helder L.; Barroso, Maria K. de A., E-mail: eligenessampaio@hotmail.com [Universidade Federal Ceara (UFC), Fortaleza, CE (Brazil); Barros, Matheus de O. [Instituto Federal do Ceara (IFCE), Fortaleza, CE (Brazil); Morais, Joao P.S. [Embrapa Algodao, Campina Grande, PB (Brazil); Borges, Maria de F.; Rosa, Morsyleide de F. [Embrapa Agroindustria Tropical, Fortaleza, CE (Brazil)

2015-07-01

The aim of this study was to characterize the TEMPO-oxidized bacterial cellulose, as a preliminary research for further application in nanocomposites. Bacterial cellulose (BC) was selectively oxidized at C-6 carbon by TEMPO radical. Oxidized bacterial cellulose (BCOX) was characterized by TGA, FTIR, XRD, and zeta potential. BCOX suspension was stable at pH 7.0, presented a crystallinity index of 83%, in spite of 92% of BC, because of decrease in the free hydroxyl number. FTIR spectra showed characteristic BC bands and, in addition, band of carboxylic group, proving the oxidation. BCOX DTG showed, in addition to characteristic BC thermal events, a maximum degradation peak at 233 °C, related to sodium anhydro-glucuronate groups formed during the cellulose oxidation. Thus, BC can be TEMPO-oxidized without great loss in its structure and properties. (author)

Spontaneous Entrainment of Running Cadence to Music Tempo.

Science.gov (United States)

Van Dyck, Edith; Moens, Bart; Buhmann, Jeska; Demey, Michiel; Coorevits, Esther; Dalla Bella, Simone; Leman, Marc

Since accumulating evidence suggests that step rate is strongly associated with running-related injuries, it is important for runners to exercise at an appropriate running cadence. As music tempo has been shown to be capable of impacting exercise performance of repetitive endurance activities, it might also serve as a means to (re)shape running cadence. The aim of this study was to validate the impact of music tempo on running cadence. Sixteen recreational runners ran four laps of 200 m (i.e. 800 m in total); this task was repeated 11 times with a short break in between each four-lap sequence. During the first lap of a sequence, participants ran at a self-paced tempo without musical accompaniment. Running cadence of the first lap was registered, and during the second lap, music with a tempo matching the assessed cadence was played. In the final two laps, the music tempo was either increased/decreased by 3.00, 2.50, 2.00, 1.50, or 1.00 % or was kept stable. This range was chosen since the aim of this study was to test spontaneous entrainment (an average person can distinguish tempo variations of about 4 %). Each participant performed all conditions. Imperceptible shifts in musical tempi in proportion to the runner's self-paced running tempo significantly influenced running cadence ( p  tempo conditions and adaptation in running cadence ( p  effect of condition on the level of entrainment was revealed ( p  effects of music tempo on running cadence can only be obtained up to a certain level of tempo modification. Finally, significantly higher levels of tempo entrainment were found for female participants compared to their male counterparts ( p  music tempo could serve as an unprompted means to impact running cadence. As increases in step rate may prove beneficial in the prevention and treatment of common running-related injuries, this finding could be especially relevant for treatment purposes, such as exercise prescription and gait retraining. Music tempo

Memory for vocal tempo and pitch.

Science.gov (United States)

Boltz, Marilyn G

2017-11-01

Two experiments examined the ability to remember the vocal tempo and pitch of different individuals, and the way this information is encoded into the cognitive system. In both studies, participants engaged in an initial familiarisation phase while attending was systematically directed towards different aspects of speakers' voices. Afterwards, they received a tempo or pitch recognition task. Experiment 1 showed that tempo and pitch are both incidentally encoded into memory at levels comparable to intentional learning, and no performance deficit occurs with divided attending. Experiment 2 examined the ability to recognise pitch or tempo when the two dimensions co-varied and found that the presence of one influenced the other: performance was best when both dimensions were positively correlated with one another. As a set, these findings indicate that pitch and tempo are automatically processed in a holistic, integral fashion [Garner, W. R. (1974). The processing of information and structure. Potomac, MD: Erlbaum.] which has a number of cognitive implications.

Tempos históricos, tempos físicos, tempos epidemiológicos: prováveis contribuições de Fernand Braudel e Ilya Prigogine ao pensamento epidemiológico

Directory of Open Access Journals (Sweden)

Sevalho Gil

1997-01-01

Full Text Available O texto é uma abordagem acerca do tempo enquanto categoria científica para a epidemiologia. A partir do aforismo tempo-lugar-pessoa, o tempo é apontado como elemento pouco pensado pela epidemiologia, embora esteja presente em vários dos seus conceitos. No entanto, o tema tem sido objeto de reflexão importante na movimentação recente de várias disciplinas, tais como a história, a geografia, a biologia e a física, e deve por isto representar para a epidemiologia um ponto de vista interessante, tanto no que concerne ao diálogo interdisciplinar quanto ao estabelecimento de um olhar crítico voltado para a própria disciplina. Com o objetivo de argumentar a respeito destes aspectos, apresenta-se o tempo histórico de Fernand Braudel e o tempo físico de Ilya Prigogine, construções teóricas que serão comparadas com um provável tempo epidemiológico. Ao final, usando a questão das infecções emergentes como exemplo, faz-se considerações sobre a aparente inadequação epistemológica do tempo epidemiológico para reconhecer e lidar com os aspectos sociais e históricos envolvidos na complexidade do adoecer humano coletivo.

Increase in salivary oxytocin and decrease in salivary cortisol after listening to relaxing slow-tempo and exciting fast-tempo music.

Directory of Open Access Journals (Sweden)

Yuuki Ooishi

Full Text Available Relaxation and excitation are components of the effects of music listening. The tempo of music is often considered a critical factor when determining these effects: listening to slow-tempo and fast-tempo music elicits relaxation and excitation, respectively. However, the chemical bases that underlie these relaxation and excitation effects remain unclear. Since parasympathetic and sympathetic nerve activities are facilitated by oxytocin and glucocorticoid, respectively, we hypothesized that listening to relaxing slow-tempo and exciting fast-tempo music is accompanied by increases in the oxytocin and cortisol levels, respectively. We evaluated the change in the salivary oxytocin and cortisol levels of participants listening to slow-tempo and fast-tempo music sequences. We measured the heart rate (HR and calculated the heart rate variability (HRV to evaluate the strength of autonomic nerve activity. After listening to a music sequence, the participants rated their arousal and valence levels. We found that both the salivary oxytocin concentration and the high frequency component of the HRV (HF increased and the HR decreased when a slow-tempo music sequence was presented. The salivary cortisol level decreased and the low frequency of the HRV (LF to HF ratio (LF/HF increased when a fast-tempo music sequence was presented. The ratio of the change in the oxytocin level was correlated with the change in HF, LF/HF and HR, whereas that in the cortisol level did not show any correlation with indices of autonomic nerve activity. There was no correlation between the change in oxytocin level and self-reported emotions, while the change in cortisol level correlated with the arousal level. These findings suggest that listening to slow-tempo and fast-tempo music is accompanied by an increase in the oxytocin level and a decrease in the cortisol level, respectively, and imply that such music listening-related changes in oxytocin and cortisol are involved in

Increase in salivary oxytocin and decrease in salivary cortisol after listening to relaxing slow-tempo and exciting fast-tempo music

Science.gov (United States)

Watanabe, Ken; Kawato, Suguru; Kashino, Makio

2017-01-01

Relaxation and excitation are components of the effects of music listening. The tempo of music is often considered a critical factor when determining these effects: listening to slow-tempo and fast-tempo music elicits relaxation and excitation, respectively. However, the chemical bases that underlie these relaxation and excitation effects remain unclear. Since parasympathetic and sympathetic nerve activities are facilitated by oxytocin and glucocorticoid, respectively, we hypothesized that listening to relaxing slow-tempo and exciting fast-tempo music is accompanied by increases in the oxytocin and cortisol levels, respectively. We evaluated the change in the salivary oxytocin and cortisol levels of participants listening to slow-tempo and fast-tempo music sequences. We measured the heart rate (HR) and calculated the heart rate variability (HRV) to evaluate the strength of autonomic nerve activity. After listening to a music sequence, the participants rated their arousal and valence levels. We found that both the salivary oxytocin concentration and the high frequency component of the HRV (HF) increased and the HR decreased when a slow-tempo music sequence was presented. The salivary cortisol level decreased and the low frequency of the HRV (LF) to HF ratio (LF/HF) increased when a fast-tempo music sequence was presented. The ratio of the change in the oxytocin level was correlated with the change in HF, LF/HF and HR, whereas that in the cortisol level did not show any correlation with indices of autonomic nerve activity. There was no correlation between the change in oxytocin level and self-reported emotions, while the change in cortisol level correlated with the arousal level. These findings suggest that listening to slow-tempo and fast-tempo music is accompanied by an increase in the oxytocin level and a decrease in the cortisol level, respectively, and imply that such music listening-related changes in oxytocin and cortisol are involved in physiological

Increase in salivary oxytocin and decrease in salivary cortisol after listening to relaxing slow-tempo and exciting fast-tempo music.

Science.gov (United States)

Ooishi, Yuuki; Mukai, Hideo; Watanabe, Ken; Kawato, Suguru; Kashino, Makio

2017-01-01

Relaxation and excitation are components of the effects of music listening. The tempo of music is often considered a critical factor when determining these effects: listening to slow-tempo and fast-tempo music elicits relaxation and excitation, respectively. However, the chemical bases that underlie these relaxation and excitation effects remain unclear. Since parasympathetic and sympathetic nerve activities are facilitated by oxytocin and glucocorticoid, respectively, we hypothesized that listening to relaxing slow-tempo and exciting fast-tempo music is accompanied by increases in the oxytocin and cortisol levels, respectively. We evaluated the change in the salivary oxytocin and cortisol levels of participants listening to slow-tempo and fast-tempo music sequences. We measured the heart rate (HR) and calculated the heart rate variability (HRV) to evaluate the strength of autonomic nerve activity. After listening to a music sequence, the participants rated their arousal and valence levels. We found that both the salivary oxytocin concentration and the high frequency component of the HRV (HF) increased and the HR decreased when a slow-tempo music sequence was presented. The salivary cortisol level decreased and the low frequency of the HRV (LF) to HF ratio (LF/HF) increased when a fast-tempo music sequence was presented. The ratio of the change in the oxytocin level was correlated with the change in HF, LF/HF and HR, whereas that in the cortisol level did not show any correlation with indices of autonomic nerve activity. There was no correlation between the change in oxytocin level and self-reported emotions, while the change in cortisol level correlated with the arousal level. These findings suggest that listening to slow-tempo and fast-tempo music is accompanied by an increase in the oxytocin level and a decrease in the cortisol level, respectively, and imply that such music listening-related changes in oxytocin and cortisol are involved in physiological

Evolutionary speed limited by water in arid Australia.

Science.gov (United States)

Goldie, Xavier; Gillman, Len; Crisp, Mike; Wright, Shane

2010-09-07

The covariation of biodiversity with climate is a fundamental pattern in nature. However, despite the ubiquity of this relationship, a consensus on the ultimate cause remains elusive. The evolutionary speed hypothesis posits direct mechanistic links between ambient temperature, the tempo of micro-evolution and, ultimately, species richness. Previous research has demonstrated faster rates of molecular evolution in warmer climates for a broad range of poikilothermic and homeothermic organisms, in both terrestrial and aquatic environments. In terrestrial systems, species richness increases with both temperature and water availability and the interaction of those terms: productivity. However, the influence of water availability as an independent variable on micro-evolutionary processes has not been examined previously. Here, using methodology that limits the potentially confounding role of cladogenetic and demographic processes, we report, to our knowledge, the first evidence that woody plants living in the arid Australian Outback are evolving more slowly than related species growing at similar latitudes in moist habitats on the mesic continental margins. These results support a modified evolutionary speed explanation for the relationship between the water-energy balance and plant diversity patterns.

Tempo and mode of performance evolution across multiple independent origins of adhesive toe pads in lizards.

Science.gov (United States)

Hagey, Travis J; Uyeda, Josef C; Crandell, Kristen E; Cheney, Jorn A; Autumn, Kellar; Harmon, Luke J

2017-10-01

Understanding macroevolutionary dynamics of trait evolution is an important endeavor in evolutionary biology. Ecological opportunity can liberate a trait as it diversifies through trait space, while genetic and selective constraints can limit diversification. While many studies have examined the dynamics of morphological traits, diverse morphological traits may yield the same or similar performance and as performance is often more proximately the target of selection, examining only morphology may give an incomplete understanding of evolutionary dynamics. Here, we ask whether convergent evolution of pad-bearing lizards has followed similar evolutionary dynamics, or whether independent origins are accompanied by unique constraints and selective pressures over macroevolutionary time. We hypothesized that geckos and anoles each have unique evolutionary tempos and modes. Using performance data from 59 species, we modified Brownian motion (BM) and Ornstein-Uhlenbeck (OU) models to account for repeated origins estimated using Bayesian ancestral state reconstructions. We discovered that adhesive performance in geckos evolved in a fashion consistent with Brownian motion with a trend, whereas anoles evolved in bounded performance space consistent with more constrained evolution (an Ornstein-Uhlenbeck model). Our results suggest that convergent phenotypes can have quite distinctive evolutionary patterns, likely as a result of idiosyncratic constraints or ecological opportunities. © 2017 The Author(s). Evolution © 2017 The Society for the Study of Evolution.

Tensão entre tempo social e tempo individual The tension between social time and individual time

Directory of Open Access Journals (Sweden)

Josué Pereira da Silva

2009-01-01

Full Text Available O artigo discute o tempo na obra de André Gorz, procurando a partir desse tema compreender sua concepção a respeito da relação entre indivíduo e sociedade. Para tanto, identifica e descreve suas três abordagens sobre o tempo: a primeira procura construir uma axiologia de valores baseada nas três dimensões temporais (passado, presente e futuro; a segunda discute a relação entre tempo e envelhecimento; e a terceira trata do tempo de trabalho. Após descrever cada uma dessas três abordagens sobre o tempo, o artigo conclui sugerindo que há uma tensão entre tempo social e tempo do indivíduo na teoria desse autor, tensão que decorre em boa medida de uma visão filosófica que concebe indivíduo e sociedade como entidades quase antagônicas.The article explores the theme of time in the work of André Gorz, using this motif as a basis for understanding his conception of the relationship between individual and society. This aim in mind, it identifies and describes his three approaches to time: the first seeks to construct an axiology of values based on the three temporal dimensions (past, present and future; the second examines the relationship between time and aging; and the third deals with the time of work. After describing each of these three approaches, the article concludes by identifying the tension between social time and individual time in the author's theory, a tension that largely arises from a philosophical viewpoint that conceives individual and society as almost antagonistic entities.

Effects of Some Aspects of Rhythm on Tempo Perception.

Science.gov (United States)

Wang, Cecilia Chu

1984-01-01

Results indicated that significantly more time is needed to perceive tempo increase than tempo decrease, uneven rhythm then even rhythm, and melody alone than melody with accompaniment. Furthermore, significant interaction effects involving beat locations of tempo change suggest that differential groupings may be a factor in tempo discrimination.…

Context effects on tempo and pleasantness judgments for Beatles songs.

Science.gov (United States)

Rashotte, Matthew A; Wedell, Douglas H

2012-04-01

Context effects on tempo and pleasantness judgments of different tempos were demonstrated in three experiments using Beatles songs. In Experiments 1 and 2, we explored how listening to versions of the same song that were played at different tempos affected tempo and pleasantness ratings. In both experiments, contrast effects were found on judgments of tempo, with target tempos rated faster when context tempos were slow than when they were fast. In both experiments, we also showed that the peak of the pleasantness rating function shifted toward the values of the context tempos, reflecting disordinal context effects on pleasantness relationships. Familiarity with the songs did not moderate these effects, and shifts in tempo ratings did not correlate with shifts in most pleasant target tempos when context was manipulated within subjects. In Experiment 3, we examined how manipulations of context tempos for one song affected judgments of the same song as compared with judgments of other more or less similar songs. For tempo ratings, contrast effects transferred to ratings of a similar song, but for pleasantness ratings, assimilative shifts of ideals were found only for the same song and not for similar songs. This pattern of results was supportive of independent bases for the two context effects.

Relationship between exercise heart rate and music tempo preference.

Science.gov (United States)

Karageorghis, Costas I; Jones, Leighton; Low, Daniel C

2006-06-01

The present study examined the predicted positive and linear relationship (Iwanaga, 1995a, 1995b) between exercise heart rate and music tempo preference. Initially, 128 undergraduate students (M age = 20.0 years, SD = 0.9) were surveyed to establish their three favorite music artists. A separate experimental group of 29 undergraduates (M age = 20.3 years, SD = 1.2) selected the music of a single artist from the three highest-rated artists from the earlier survey. They reported their preference for slow, medium, and fast tempo selections from each artist for three treadmill walking conditions at 40%, 60%, and 75% maximal heart rate reserve. A mixed-model 3 x 3 x 2 (Exercise Intensity x Music Tempo x Gender) analysis of variance was used to analyze the data. Results indicated there was no three-way interaction for music preference. There was, however, a significant (p Music Tempo (partial eta2 = .09) and a significant (p effect for music tempo, with large differences evident between preference for medium versus slow tempo and fast versus slow tempo music at all exercise intensities (partial eta2 = .78). Participants reported a preference for both medium and fast tempo music at low and moderate exercise intensities and for fast tempo music at high intensity. Only partial support was found for the expected linear relationship between exercise intensity and music tempo preference.

Modalization in the Political Column of Tempo Magazine

OpenAIRE

Rahmah, Maria Betti Sinaga and

2017-01-01

The study focuses on analyzing the use of modalization in the Political Column of Tempo Magazine. The objectives were to find out the type of modalization and to describe the use of modalization in the Political Column of Tempo magazine. The data were taken from Political Column of Tempo magazine published in June and July 2017. The source of data was Political Column in Tempo magazine. The data analysis applied descriptive qualitative research. There were 135 clauses which contained Modaliza...

Automatic movie skimming with general tempo analysis

Science.gov (United States)

Lee, Shih-Hung; Yeh, Chia-Hung; Kuo, C. C. J.

2003-11-01

Story units are extracted by general tempo analysis including tempos analysis including tempos of audio and visual information in this research. Although many schemes have been proposed to successfully segment video data into shots using basic low-level features, how to group shots into meaningful units called story units is still a challenging problem. By focusing on a certain type of video such as sport or news, we can explore models with the specific application domain knowledge. For movie contents, many heuristic rules based on audiovisual clues have been proposed with limited success. We propose a method to extract story units using general tempo analysis. Experimental results are given to demonstrate the feasibility and efficiency of the proposed technique.

On tempo tracking: Tempogram representation and Kalman filtering

NARCIS (Netherlands)

Cemgil, A.T.; Kappen, H.J.; Desain, P.W.M.; Honing, H.J.

2001-01-01

We formulate tempo tracking in a Bayesian framework where a tempo tracker is modeled as a stochastic dynamical system. The tempo is modeled as a hidden state variable of the system and is estimated by a Kalman filter. The Kalman filter operates on a Tempogram, a wavelet-like multiscale expansion of

Tropospheric emissions: Monitoring of pollution (TEMPO)

Science.gov (United States)

Zoogman, P.; Liu, X.; Suleiman, R. M.; Pennington, W. F.; Flittner, D. E.; Al-Saadi, J. A.; Hilton, B. B.; Nicks, D. K.; Newchurch, M. J.; Carr, J. L.; Janz, S. J.; Andraschko, M. R.; Arola, A.; Baker, B. D.; Canova, B. P.; Chan Miller, C.; Cohen, R. C.; Davis, J. E.; Dussault, M. E.; Edwards, D. P.; Fishman, J.; Ghulam, A.; González Abad, G.; Grutter, M.; Herman, J. R.; Houck, J.; Jacob, D. J.; Joiner, J.; Kerridge, B. J.; Kim, J.; Krotkov, N. A.; Lamsal, L.; Li, C.; Lindfors, A.; Martin, R. V.; McElroy, C. T.; McLinden, C.; Natraj, V.; Neil, D. O.; Nowlan, C. R.; O`Sullivan, E. J.; Palmer, P. I.; Pierce, R. B.; Pippin, M. R.; Saiz-Lopez, A.; Spurr, R. J. D.; Szykman, J. J.; Torres, O.; Veefkind, J. P.; Veihelmann, B.; Wang, H.; Wang, J.; Chance, K.

2017-01-01

TEMPO was selected in 2012 by NASA as the first Earth Venture Instrument, for launch between 2018 and 2021. It will measure atmospheric pollution for greater North America from space using ultraviolet and visible spectroscopy. TEMPO observes from Mexico City, Cuba, and the Bahamas to the Canadian oil sands, and from the Atlantic to the Pacific, hourly and at high spatial resolution ( 2.1 km N/S×4.4 km E/W at 36.5°N, 100°W). TEMPO provides a tropospheric measurement suite that includes the key elements of tropospheric air pollution chemistry, as well as contributing to carbon cycle knowledge. Measurements are made hourly from geostationary (GEO) orbit, to capture the high variability present in the diurnal cycle of emissions and chemistry that are unobservable from current low-Earth orbit (LEO) satellites that measure once per day. The small product spatial footprint resolves pollution sources at sub-urban scale. Together, this temporal and spatial resolution improves emission inventories, monitors population exposure, and enables effective emission-control strategies. TEMPO takes advantage of a commercial GEO host spacecraft to provide a modest cost mission that measures the spectra required to retrieve ozone (O3), nitrogen dioxide (NO2), sulfur dioxide (SO2), formaldehyde (H2CO), glyoxal (C2H2O2), bromine monoxide (BrO), IO (iodine monoxide), water vapor, aerosols, cloud parameters, ultraviolet radiation, and foliage properties. TEMPO thus measures the major elements, directly or by proxy, in the tropospheric O3 chemistry cycle. Multi-spectral observations provide sensitivity to O3 in the lowermost troposphere, substantially reducing uncertainty in air quality predictions. TEMPO quantifies and tracks the evolution of aerosol loading. It provides these near-real-time air quality products that will be made publicly available. TEMPO will launch at a prime time to be the North American component of the global geostationary constellation of pollution monitoring

Tropospheric Emissions: Monitoring of Pollution (TEMPO)

Science.gov (United States)

Zoogman, P.; Liu, X.; Suleiman, R. M.; Pennington, W. F.; Flittner, D. E.; Al-Saadi, J. A.; Hilton, B. B.; Nicks, D. K.; Newchurch, M. J.; Carr, J. L.;

Nonhuman primates prefer slow tempos but dislike music overall.

Science.gov (United States)

McDermott, Josh; Hauser, Marc D

2007-09-01

Human adults generally find fast tempos more arousing than slow tempos, with tempo frequently manipulated in music to alter tension and emotion. We used a previously published method [McDermott, J., & Hauser, M. (2004). Are consonant intervals music to their ears? Spontaneous acoustic preferences in a nonhuman primate. Cognition, 94(2), B11-B21] to test cotton-top tamarins and common marmosets, two new-World primates, for their spontaneous responses to stimuli that varied systematically with respect to tempo. Across several experiments, we found that both tamarins and marmosets preferred slow tempos to fast. It is possible that the observed preferences were due to arousal, and that this effect is homologous to the human response to tempo. In other respects, however, these two monkey species showed striking differences compared to humans. Specifically, when presented with a choice between slow tempo musical stimuli, including lullabies, and silence, tamarins and marmosets preferred silence whereas humans, when similarly tested, preferred music. Thus despite the possibility of homologous mechanisms for tempo perception in human and nonhuman primates, there appear to be motivational ties to music that are uniquely human.

Avoiding Local Optima with Interactive Evolutionary Robotics

Science.gov (United States)

2012-07-09

the top of a flight of stairs selects for climbing ; suspending the robot and the target object above the ground and creating rungs between the two will...REPORT Avoiding Local Optimawith Interactive Evolutionary Robotics 14. ABSTRACT 16. SECURITY CLASSIFICATION OF: The main bottleneck in evolutionary... robotics has traditionally been the time required to evolve robot controllers. However with the continued acceleration in computational resources, the

Effect of Tempo on Pitch Perception.

Science.gov (United States)

Duke, Robert A.; And Others

1988-01-01

Presents a study which investigated the perception of music majors and nonmusic majors concerning their ability to discriminate the way in which altered musical excerpts differed in pitch or tempo (or both) from preceding presentations. Concludes that both groups responded similarly across conditions and replications, and that tempo changes were…

Increase in salivary oxytocin and decrease in salivary cortisol after listening to relaxing slow-tempo and exciting fast-tempo music

OpenAIRE

Ooishi, Yuuki; Mukai, Hideo; Watanabe, Ken; Kawato, Suguru; Kashino, Makio

2017-01-01

Relaxation and excitation are components of the effects of music listening. The tempo of music is often considered a critical factor when determining these effects: listening to slow-tempo and fast-tempo music elicits relaxation and excitation, respectively. However, the chemical bases that underlie these relaxation and excitation effects remain unclear. Since parasympathetic and sympathetic nerve activities are facilitated by oxytocin and glucocorticoid, respectively, we hypothesized that li...

The Morphological Analysis Found in Tempo Magazine

OpenAIRE

Lubis, Khairunnisa

2015-01-01

A paper entitled “The Morphological Analysis Found in Tempo Magazine” discussed about affixation process that is one of field linguistics, Morphology. The data of this research is five articles in Tempo magazine 1405/September 23-29, 2013. The scope of this writing is to find some kinds of prefixes and suffixes are used in Tempo magazine and to find what the dominant affix is. The method of research applied is descriptive qualitative. After analyzing the data, there are 5 kinds of prefixes, n...

Implementation of Tropospheric Emissions: Monitoring of Pollution (TEMPO)

Science.gov (United States)

Chance, K.; Liu, X.; Suleiman, R. M.; Flittner, D. E.; Al-Saadi, J. A.; Janz, S. J.

2014-12-01

The updated status of TEMPO, as it proceeds from formulation phase into implementation phase is presented. TEMPO, the first NASA Earth Venture Instrument, will measure atmospheric pollution for greater North America from space using ultraviolet and visible spectroscopy. TEMPO measures from Mexico City to the Canadian oil sands, and from the Atlantic to the Pacific, hourly and at high spatial resolution. TEMPO provides a tropospheric measurement suite that includes the key elements of tropospheric air pollution chemistry. Measurements are from geostationary (GEO) orbit, to capture the inherent high variability in the diurnal cycle of emissions and chemistry. The small product spatial footprint resolves pollution sources at sub-urban scale. Together, this temporal and spatial resolution improves emission inventories, monitors population exposure, and enables effective emission-control strategies. TEMPO takes advantage of a GEO host spacecraft to provide a modest cost mission that measures the spectra required to retrieve O3, NO2, SO2, H2CO, C2H2O2, H2O, aerosols, cloud parameters, and UVB radiation. TEMPO thus measures the major elements, directly or by proxy, in the tropospheric O3 chemistry cycle. Multi-spectral observations provide sensitivity to O3 in the lowermost troposphere, reducing uncertainty in air quality predictions by 50%. TEMPO quantifies and tracks the evolution of aerosol loading. It provides near-real-time air quality products that will be made widely, publicly available. TEMPO provides much of the atmospheric measurement capability recommended for GEO-CAPE in the 2007 National Research Council Decadal Survey, Earth Science and Applications from Space: National Imperatives for the Next Decade and Beyond. GEO-CAPE is not planned for implementation this decade. However, instruments from Europe (Sentinel 4) and Asia (GEMS) will form parts of a global GEO constellation for pollution monitoring later this decade, with a major focus on intercontinental

Diligencia de estudantes de graduação de tempo integral e tempo parcial

OpenAIRE

Eliel Unglaub

2003-01-01

Resumo: Este estudo teve por objetivo descrever, discutir e analisar a manifestação de diligência dos estudantes de graduação de Tempo integral e Tempo parcial, em suas múltiplas dimensões, tais como: Disciplina, Conformidade e Responsabilidade, Motivação, Devoção e Espiritualidade e Concentração e Assimilação, em cursos pré-selecionados da UNICAMP. Procurou-se descobrir em que medida outros fatores, tais como: sexo, estado civil, idade, trabalho, turno e renda familiar estão relacionados à d...

The Effect of Speed Alterations on Tempo Note Selection.

Science.gov (United States)

Madsen, Clifford K.; And Others

1986-01-01

Investigated the tempo note preferences of 100 randomly selected college-level musicians using familiar orchestral music as stimuli. Subjects heard selections at increased, decreased, and unaltered tempi. Results showed musicians were not accurate in estimating original tempo and showed consistent preference for faster than actual tempo.…

La trama del cosmo spazio, tempo, realtà

CERN Document Server

Greene, Brian

2004-01-01

Dal regno immutabile di Newton, dove lo spazio e il tempo sono assoluti, alla concezione fluida dello spazio-tempo di Einstein, alle tesi della meccanica quantistica, il fisico americano mostra come il mondo sia molto diverso da quello che l'esperienza comune potrebbe far pensare. Concentrandosi sull'enigma del tempo, Greene stabilisce che nessuna regola fisica conferma l'idea che esso scorra in una particolare direzione. Attraverso l'analisi della teoria del big bang, dimostra quanto le recenti teorie delle superstringhe e la M-teoria possano conciliare ogni cosa, dalla più piccola particella al più grande buco nero. Una visione che culmina in un "multiverso" dove spazio e tempo possono dissolversi in entità più sottili e fondamentali.

Absolute Memory for Tempo in Musicians and Non-Musicians.

Directory of Open Access Journals (Sweden)

Irene Gratton

Full Text Available The ability to remember tempo (the perceived frequency of musical pulse without external references may be defined, by analogy with the notion of absolute pitch, as absolute tempo (AT. Anecdotal reports and sparse empirical evidence suggest that at least some individuals possess AT. However, to our knowledge, no systematic assessments of AT have been performed using laboratory tasks comparable to those assessing absolute pitch. In the present study, we operationalize AT as the ability to identify and reproduce tempo in the absence of rhythmic or melodic frames of reference and assess these abilities in musically trained and untrained participants. We asked 15 musicians and 15 non-musicians to listen to a seven-step `tempo scale' of metronome beats, each associated to a numerical label, and then to perform two memory tasks. In the first task, participants heard one of the tempi and attempted to report the correct label (identification task, in the second, they saw one label and attempted to tap the correct tempo (production task. A musical and visual excerpt was presented between successive trials as a distractor to prevent participants from using previous tempi as anchors. Thus, participants needed to encode tempo information with the corresponding label, store the information, and recall it to give the response. We found that more than half were able to perform above chance in at least one of the tasks, and that musical training differentiated between participants in identification, but not in production. These results suggest that AT is relatively wide-spread, relatively independent of musical training in tempo production, but further refined by training in tempo identification. We propose that at least in production, the underlying motor representations are related to tactus, a basic internal rhythmic period that may provide a body-based reference for encoding tempo.

Tempo of trophic evolution and its impact on mammalian diversification.

Science.gov (United States)

Price, Samantha A; Hopkins, Samantha S B; Smith, Kathleen K; Roth, V Louise

2012-05-01

Mammals are characterized by the complex adaptations of their dentition, which are an indication that diet has played a critical role in their evolutionary history. Although much attention has focused on diet and the adaptations of specific taxa, the role of diet in large-scale diversification patterns remains unresolved. Contradictory hypotheses have been proposed, making prediction of the expected relationship difficult. We show that net diversification rate (the cumulative effect of speciation and extinction), differs significantly among living mammals, depending upon trophic strategy. Herbivores diversify fastest, carnivores are intermediate, and omnivores are slowest. The tempo of transitions between the trophic strategies is also highly biased: the fastest rates occur into omnivory from herbivory and carnivory and the lowest transition rates are between herbivory and carnivory. Extant herbivore and carnivore diversity arose primarily through diversification within lineages, whereas omnivore diversity evolved by transitions into the strategy. The ability to specialize and subdivide the trophic niche allowed herbivores and carnivores to evolve greater diversity than omnivores.

Preferred Dance Tempo

DEFF Research Database (Denmark)

Dahl, Sofia; Huron, David; Brod, Garvin

2014-01-01

In two experiments participants tuned a drum machine to their preferred dance tempo. Measurements of height, shoulder width, leg length, and weight were taken for each participant, and their sex recorded. Using a multiple regression analysis, height and leg length combined was found to be the bes...

Aspirin degradation in surface-charged TEMPO-oxidized mesoporous crystalline nanocellulose.

Science.gov (United States)

Carlsson, Daniel O; Hua, Kai; Forsgren, Johan; Mihranyan, Albert

2014-01-30

TEMPO-mediated surface oxidation of mesoporous highly crystalline Cladophora cellulose was used to introduce negative surface charges onto cellulose nanofibrils without significantly altering other structural characteristics. This enabled the investigation of the influence of mesoporous nanocellulose surface charges on aspirin chemical stability to be conducted. The negative surface charges (carboxylate content 0.44±0.01 mmol/g) introduced on the mesoporous crystalline nanocellulose significantly accelerated aspirin degradation, compared to the starting material which had significantly less surface charge (0.06±0.01 mmol/g). This effect followed from an increased aspirin amorphisation ability in mesopores of the oxidized nanocellulose. These results highlight the importance of surface charges in formulating nanocellulose for drug delivery. Copyright © 2013 Elsevier B.V. All rights reserved.

Characterization of TEMPO-oxidized bacterial cellulose

International Nuclear Information System (INIS)

Nascimento, Eligenes S.; Pereira, Andre L.S.; Lima, Helder L.; Barroso, Maria K. de A.; Barros, Matheus de O.; Morais, Joao P.S.; Borges, Maria de F.; Rosa, Morsyleide de F.

2015-01-01

The aim of this study was to characterize the TEMPO-oxidized bacterial cellulose, as a preliminary research for further application in nanocomposites. Bacterial cellulose (BC) was selectively oxidized at C-6 carbon by TEMPO radical. Oxidized bacterial cellulose (BCOX) was characterized by TGA, FTIR, XRD, and zeta potential. BCOX suspension was stable at pH 7.0, presented a crystallinity index of 83%, in spite of 92% of BC, because of decrease in the free hydroxyl number. FTIR spectra showed characteristic BC bands and, in addition, band of carboxylic group, proving the oxidation. BCOX DTG showed, in addition to characteristic BC thermal events, a maximum degradation peak at 233 °C, related to sodium anhydro-glucuronate groups formed during the cellulose oxidation. Thus, BC can be TEMPO-oxidized without great loss in its structure and properties. (author)

Tempo Preferences of Different Age Music Listeners.

Science.gov (United States)

LeBlanc, Albert; And Others

1988-01-01

Measures the effect of four levels of tempo on the self-reported preferences of six different age-groups for traditional jazz music listening examples. Stated that listener age exerted a strong influence on overall preference scores. Reported an analysis of variance showing that there is a significant preference for increasingly faster tempo at…

Carbon aerogels by pyrolysis of TEMPO-oxidized cellulose

Science.gov (United States)

Zhang, Sizhao; Feng, Jian; Feng, Junzong; Jiang, Yonggang; Ding, Feng

2018-05-01

Although carbon aerogels derived from naturally occurring materials have been developed extensively, a reasonable synthetic approach using cellulose-resource remains unclear. Here, we report a strategy to prepare carbon aerogels originated from cellulose position-selectively oxidized by TEMPO-oxidized process. Contrary to non-TEMPO-oxidized cellulose-derived carbon aerogels (NCCA) with relative loose structure, TEMPO-oxidized cellulose-derived carbon aerogels (TCCA) with tight fibrillar-continuous network are monitored, suggesting the importance of TEMPO-oxidized modification towards creating the architecture of subsequently produced carbon aerogels. TCCA endows a higher BET area despite owning slightly dense bulk density comparing with that of NCCA. The structural texture of TCCA could be maintained in a way in comparison to TEMPO-oxidized cellulose-derived aerogel, due to the integration and aggregation effect by losing the electric double layer repulsion via ionization of the surface carboxyl groups. FTIR and XPS analyses signify the evidence of non-functionalized carbon-skeleton network formation in terms of TCCA. Further, the mechanism concerning the creation of carbon aerogels is also established. These findings not only provide new insights into the production of carbon aerogels but also open up a new opportunity in the field of functional carbon materials.

Sympathetic Tone Induced by High Acoustic Tempo Requires Fast Respiration.

Directory of Open Access Journals (Sweden)

Ken Watanabe

Full Text Available Many studies have revealed the influences of music, and particularly its tempo, on the autonomic nervous system (ANS and respiration patterns. Since there is the interaction between the ANS and the respiratory system, namely sympatho-respiratory coupling, it is possible that the effect of musical tempo on the ANS is modulated by the respiratory system. Therefore, we investigated the effects of the relationship between musical tempo and respiratory rate on the ANS. Fifty-two healthy people aged 18-35 years participated in this study. Their respiratory rates were controlled by using a silent electronic metronome and they listened to simple drum sounds with a constant tempo. We varied the respiratory rate-acoustic tempo combination. The respiratory rate was controlled at 15 or 20 cycles per minute (CPM and the acoustic tempo was 60 or 80 beats per minute (BPM or the environment was silent. Electrocardiograms and an elastic chest band were used to measure the heart rate and respiratory rate, respectively. The mean heart rate and heart rate variability (HRV were regarded as indices of ANS activity. We observed a significant increase in the mean heart rate and the low (0.04-0.15 Hz to high (0.15-0.40 Hz frequency ratio of HRV, only when the respiratory rate was controlled at 20 CPM and the acoustic tempo was 80 BPM. We suggest that the effect of acoustic tempo on the sympathetic tone is modulated by the respiratory system.

Sympathetic Tone Induced by High Acoustic Tempo Requires Fast Respiration.

Science.gov (United States)

Watanabe, Ken; Ooishi, Yuuki; Kashino, Makio

2015-01-01

Many studies have revealed the influences of music, and particularly its tempo, on the autonomic nervous system (ANS) and respiration patterns. Since there is the interaction between the ANS and the respiratory system, namely sympatho-respiratory coupling, it is possible that the effect of musical tempo on the ANS is modulated by the respiratory system. Therefore, we investigated the effects of the relationship between musical tempo and respiratory rate on the ANS. Fifty-two healthy people aged 18-35 years participated in this study. Their respiratory rates were controlled by using a silent electronic metronome and they listened to simple drum sounds with a constant tempo. We varied the respiratory rate-acoustic tempo combination. The respiratory rate was controlled at 15 or 20 cycles per minute (CPM) and the acoustic tempo was 60 or 80 beats per minute (BPM) or the environment was silent. Electrocardiograms and an elastic chest band were used to measure the heart rate and respiratory rate, respectively. The mean heart rate and heart rate variability (HRV) were regarded as indices of ANS activity. We observed a significant increase in the mean heart rate and the low (0.04-0.15 Hz) to high (0.15-0.40 Hz) frequency ratio of HRV, only when the respiratory rate was controlled at 20 CPM and the acoustic tempo was 80 BPM. We suggest that the effect of acoustic tempo on the sympathetic tone is modulated by the respiratory system.

Effects of Tempo and Context on Transfer of Performance Skills.

Science.gov (United States)

Duke, Robert A.; Pierce, Michael A.

1991-01-01

Discusses research that examined the effects of melodic content and performance tempo on the ability of university music majors to perform previously learned music passages in new settings. Finds tempo accuracy and pitch accuracy were adversely affected by differences between originally learned tempo and tempi at which works were later performed.…

Is expressive timing relational invariant under tempo transformation?

NARCIS (Netherlands)

Honing, H.

2007-01-01

This empirical study is concerned with examining the relation between tempo and expressive timing in music performance. This was investigated by asking listeners (N = 307) to distinguish between an original recording and a tempo-transformed version in a musical genre of their preference (jazz or

Creative Potential and Conceptual Tempo in Preschool Children.

Science.gov (United States)

Broberg, Gayle Christensen; Moran, James D., III

1988-01-01

Individual stylistic variations of creative potential and conceptual tempo were investigated in 61 preschool children. No differences between reflective and impulsive preschoolers were found on the ideational fluency measure. Conceptual tempo scores revealed greater originality scores for the fast/accurate and slow/inaccurate groups compared to…

Sniffer para redes Ethernet de tempo-real baseado em FPGA

OpenAIRE

Faria, João Pedro Puga

2008-01-01

A crescente utilização de sistemas distribuídos em aplicações de tempo-real tem levado á criação de protocolos de comunicação cada vez mais com- plexos e sofisticados. Apesar da rede Ethernet não apresentar característi- cas de tempo-real, devido ás suas vantagens, têm sido desenvolvidos muitos protocolos de comunicação tempo-real baseados em Ethernet. Nesta disser- tação é analisada a importância das arquitecturas distribuídas em aplicações de tempo-real, sendo apresentados...

Template-Based Estimation of Time-Varying Tempo

Directory of Open Access Journals (Sweden)

Peeters Geoffroy

2007-01-01

Full Text Available We present a novel approach to automatic estimation of tempo over time. This method aims at detecting tempo at the tactus level for percussive and nonpercussive audio. The front-end of our system is based on a proposed reassigned spectral energy flux for the detection of musical events. The dominant periodicities of this flux are estimated by a proposed combination of discrete Fourier transform and frequency-mapped autocorrelation function. The most likely meter, beat, and tatum over time are then estimated jointly using proposed meter/beat subdivision templates and a Viterbi decoding algorithm. The performances of our system have been evaluated on four different test sets among which three were used during the ISMIR 2004 tempo induction contest. The performances obtained are close to the best results of this contest.

INFLUENCIA DEL TEMPO DE LA MÚSICA EN LAS EMOCIONES

Directory of Open Access Journals (Sweden)

Jonathan Azael Caballero-Meneses

2010-01-01

Full Text Available Se sabe que la música puede influir en dos componentes de lasemociones: el arousal y la valencia. En particular, se ha reportadoque el tempo o rapidez de la música está directamenterelacionado con el arousal, aunque su relación con la valenciao medida de afecto no es aún clara. En este trabajo se analizóla influencia del tempo en ambos componentes mediante laexposición de 24 estudiantes de licenciatura a treinta extractosmusicales de distinto tempo. Además se evaluó la posiblemodulación de la relación tempo-valencia por el rasgo de personalidadextroversión/introversión. Los resultados confirmaronla influencia del tempo sobre el arousal, pero no sobrela valencia, así como una posible mediación de la dimensiónde personalidad introversión-extroversión sobre la valencia.

Fios que Tecem o Tempo Escolar: do ritmo padrão à simultaneidade

Directory of Open Access Journals (Sweden)

Ana Sueli Teixeira de Pinho

2017-09-01

Full Text Available Este texto tem por objetivo tecer os fios que, de modo complexo, atam e desatam, de forma silenciosa, a constituição do tempo em duas escolas com classes multisseriadas da Ilha de Maré, problematizando a ideia de ritmo padrão e apontando a simultaneidade como possibilidade para o tempo escolar. Do ponto de vista metodológico foi adotada a narrativa (autobiográfica, e a técnica de pesquisa selecionada foi a entrevista narrativa. O estudo realizado aponta que o tempo escolar, das duas escolas pesquisadas, é convidado a reconhecer a existência e a legitimidade de outros tempos, para além do seu: o tempo da maré, o tempo do trabalho, o tempo das práticas simbólicas, o tempo livre e as temporalidades dos sujeitos.

Tempo enhances heat-induced apoptosis by mitochondrial targeting of Bax

International Nuclear Information System (INIS)

Zhao, Q.-L.; Fujiwara, Y.; Kondo, T.

2003-01-01

A stable membrane-permeable nitroxide, Tempo, exerts an SOD-like antioxidant activity against ROS. Reportedly, Tempo inhibits ROS-induced thymocyte apoptosis, while 10 mM Tempo activates JNK1 to induce apoptosis in breast cancer cells. We have observed that nontoxic 5 mM Tempo enhances suboptimal hyperthermia (44 deg C/10 min)-induced apoptosis in U937 cells. Here we report the enhancing mechanism, focusing on activation and targeting of Bax to mitochondria and cytochrome c release. Methods: U937 cells were treated with either Tempo (5 mM, 37 deg C/10 min), heating (44 deg C/10 min), or Tempo-plus-heating, washed and incubated for various times up to 6 h, until assessing apoptosis, mitochondrial potential (ΔΨ>), and amount of superoxide by flow cytometry using Annexin V-FITC/PI, TMRM, and dihydroethidium, respectively. Bax, Bcl-2 and Bcl-XL, and cytochrome c were detected by western blotting, activated Bax was by immunoprecipitation, and ATP was by a luciferase assay. Bax targeting to and cytochrome c release from mitochorndria were also detected immunocytochemically under fluorescent microscopy. Results and Discussion: Treatment of U937 cells with 5 mM Tempo for 10 min at 37 deg C or suboptimal heating (44 deg C/ 10 min) alone did not induce apoptosis. The combined treatment with 5 mM Tempo and 44 deg C for 10 min dramatically induced ∼90% apoptosis in 6 h, as did the 44 deg C/30 min heating. During the enhanced apoptosis, cytochrome c release progressed. Although signals of Bcl-2, Bcl-XL and Bax in cell lysates were not altered, Bax was specifically activated and translocated to mitochondria after the combined treatment. Further, loss of ΔΨ>and decreases in superoxide and ATP progressed after the combined treatment, suggesting that the treatment may disturb mitochondrial electron transport. Thus, Tempo sensitizes the heat-induced apoptosis through (1) targeting of Bax to mitochondria and releasing cytochrome c, and (2) mitochondrial dysfunction

Passive listening to preferred motor tempo modulates corticospinal excitability.

Science.gov (United States)

Michaelis, Kelly; Wiener, Martin; Thompson, James C

2014-01-01

Rhythms are an essential characteristic of our lives, and auditory-motor coupling affects a variety of behaviors. Previous research has shown that the neural regions associated with motor system processing are coupled to perceptual rhythmic and melodic processing such that the perception of rhythmic stimuli can entrain motor system responses. However, the degree to which individual preference modulates the motor system is unknown. Recent work has shown that passively listening to metrically strong rhythms increases corticospinal excitability, as indicated by transcranial magnetic stimulation (TMS). Furthermore, this effect is modulated by high-groove music, or music that inspires movement, while neuroimaging evidence suggests that premotor activity increases with tempos occurring within a preferred tempo (PT) category. PT refers to the rate of a hypothetical endogenous oscillator that may be indicated by spontaneous motor tempo (SMT) and preferred perceptual tempo (PPT) measurements. The present study investigated whether listening to a rhythm at an individual's PT preferentially modulates motor system excitability. SMT was obtained in human participants through a tapping task in which subjects were asked to tap a response key at their most comfortable rate. Subjects listened a 10-beat tone sequence at 11 log-spaced tempos and rated their preference for each (PPT). We found that SMT and PPT measurements were correlated, indicating that preferred and produced tempos occurred at a similar rate. Crucially, single-pulse TMS delivered to left M1 during PPT judgments revealed that corticospinal excitability, measured by motor-evoked potentials (MEPs), was modulated by tempos traveling closer to individual PT. However, the specific nature of this modulation differed across individuals, with some exhibiting an increase in excitability around PT and others exhibiting a decrease. These findings suggest that auditory-motor coupling induced by rhythms is preferentially

Characterization of TEMPO-oxidized bacterial cellulose scaffolds for tissue engineering applications

International Nuclear Information System (INIS)

Luo, Honglin; Xiong, Guangyao; Hu, Da; Ren, Kaijing; Yao, Fanglian; Zhu, Yong; Gao, Chuan; Wan, Yizao

2013-01-01

Introduction of active groups on the surface of bacterial cellulose (BC) nanofibers is one of the promising routes of tailoring the performance of BC scaffolds for tissue engineering. This paper reported the introduction of aldehyde groups to BC nanofibers by 2,2,6,6-tetramethylpyperidine-1-oxy radical (TEMPO)-mediated oxidation and evaluation of the potential of the TEMPO-oxidized BC as tissue engineering scaffolds. Periodate oxidation was also conducted for comparison. Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) analyses were carried out to determine the existence of aldehyde groups on BC nanofibers and the crystallinity. In addition, properties relevant to scaffold applications such as morphology, fiber diameter, mechanical properties, and in vitro degradation were characterized. The results indicated that periodate oxidation could introduce free aldehyde to BC nanofibers and the free aldehyde groups on the TEMPO-oxidized BC tended to transfer to acetal groups. It was also found that the advantageous 3D structure of BC scaffolds remained unchanged and that no significant changes in morphology, fiber diameter, tensile structure and in vitro degradation were found after TEMPO-mediated oxidation while significant differences were observed upon periodate oxidation. The present study revealed that TEMPO-oxidation could impart BC scaffolds with new functions while did not degrade their intrinsic advantages. - Highlights: • TEMPO-mediated oxidation on BC scaffold for tissue engineering use was conducted. • TEMPO-mediated oxidation did not degrade the intrinsic advantages of BC scaffold. • TEMPO-mediated oxidation could impart BC scaffold with new functional groups. • Feasibility of TEMPO-oxidized BC as tissue engineering scaffold was confirmed

Effects of timbre and tempo change on memory for music.

Science.gov (United States)

Halpern, Andrea R; Müllensiefen, Daniel

2008-09-01

We investigated the effects of different encoding tasks and of manipulations of two supposedly surface parameters of music on implicit and explicit memory for tunes. In two experiments, participants were first asked to either categorize instrument or judge familiarity of 40 unfamiliar short tunes. Subsequently, participants were asked to give explicit and implicit memory ratings for a list of 80 tunes, which included 40 previously heard. Half of the 40 previously heard tunes differed in timbre (Experiment 1) or tempo (Experiment 2) in comparison with the first exposure. A third experiment compared similarity ratings of the tunes that varied in timbre or tempo. Analysis of variance (ANOVA) results suggest first that the encoding task made no difference for either memory mode. Secondly, timbre and tempo change both impaired explicit memory, whereas tempo change additionally made implicit tune recognition worse. Results are discussed in the context of implicit memory for nonsemantic materials and the possible differences in timbre and tempo in musical representations.

Luz e tempo na melancolia I

Directory of Open Access Journals (Sweden)

Cláudio Soares Braga Furtado

2009-12-01

Full Text Available A comparação entre as artes possibilita figurar o tempo como elemento comum entre a gravura renascentista de Dürer, a escultura romana de Laocoonte e o conto de Guimarães Rosa. A partir da leitura dessas artes distantes em forma, meios, época e lugar, descobrem-se mistérios aludidos em sutis sinais, que, se ainda não despertos na consciência criativa, estimulam interpretações. O papel da luz como unificadora das entidades tempo/espaço restabelece o princípio clássico da ut pictura poesis na leitura moderna.

Fenomenologia do tempo vivido no transtorno bipolar

Directory of Open Access Journals (Sweden)

Virginia Moreira

Full Text Available Com base na tradição da psicopatologia fenomenológica, este artigo se propõe a contribuir para a compreensão do mundo vivido do paciente bipolar, marcado por uma forte alteração do tempo vivido. Realizamos uma descrição deste tempo vivido significado de forma diferente nas oscilações de humor chamadas de fase maníaca e fase melancólica. Pensado a partir da temporalidade, na fase melancólica, o bipolar parece parar no tempo, não se lança em um devir. Na fase maníaca, o sujeito vive demasiadamente um agora como se tivesse explodido sua biografia. Concluímos que estas fases, ou dois pólos opostos no funcionamento temporal patológico do sofrimento bipolar, constituem fundamentalmente um mesmo mundo vivido.

The effect of music tempo on perceived crowding in retailing

OpenAIRE

Fiksdal, Taisiya; Hua, Wen

2016-01-01

Masteroppgave(MSc) in Master of Science in Strategic Marketing Management - Handelshøyskolen BI, 2016 In the marketing field the influence of in-store atmospherics on consumers’ shopping behavior is widely accepted. We seek to understand the effects of instore music tempo on perceived crowding and how music tempo can affect emotions, arousal and perceived control occurring in retail stores. Hence, our research questions are the following: Does music tempo influence the perce...

Tempo no museu e o museu no tempo

OpenAIRE

Monteiro, Renata; Gouvêa, Guaracira

2015-01-01

Este estudo discute o tempo mediante o lugar e objeto nos museus de ciência e técnica, apresentando diferentes abordagens teóricas a partir de uma perspectiva física e social. Este aporte subsidia a análise de discursos do público espontâneo do Museu de Artes e Ofícios, que expõe objetos históricos relacionados ao universo do trabalho, técnicas e ofícios do período pré-industrial brasileiro. Os discursos analisados mediante a metodologia do Discurso do Sujeito Coletivo tiveram como ponto de p...

Revisiting the relationship between exercise heart rate and music tempo preference.

Science.gov (United States)

Karageorghis, Costas I; Jones, Leighton; Priest, David-Lee; Akers, Rose I; Clarke, Adam; Perry, Jennifer M; Reddick, Benjamin T; Bishop, Daniel T; Lim, Harry B T

2011-06-01

In the present study, we investigated a hypothesized quartic relationship (meaning three inflection points) between exercise heart rate (HR) and preferred music tempo. Initial theoretical predictions suggested a positive linear relationship (Iwanaga, 1995a, 1995b); however, recent experimental work has shown that as exercise HR increases, step changes and plateaus that punctuate the profile of music tempo preference may occur (Karageorghis, Jones, & Stuart, 2008). Tempi bands consisted of slow (95-100 bpm), medium (115-120 bpm), fast (135-140 bpm), and very fast (155-160 bpm) music. Twenty-eight active undergraduate students cycled at exercise intensities representing 40, 50, 60, 70, 80, and 90% of their maximal HR reserve while their music preference was assessed using a 10-point scale. The Exercise Intensity x Music Tempo interaction was significant, F(6.16, 160.05) = 7.08, p music-tempo relationship (p music was not preferred at any exercise intensity, preference for fast tempo increased, relative to medium and very fast tempo music, as exercise intensity increased. The implications for the prescription of music in exercise and physical activity contexts are discussed.

Evolutionary genomics and HIV restriction factors.

Science.gov (United States)

Pyndiah, Nitisha; Telenti, Amalio; Rausell, Antonio

2015-03-01

To provide updated insights into innate antiviral immunity and highlight prototypical evolutionary features of well characterized HIV restriction factors. Recently, a new HIV restriction factor, Myxovirus resistance 2, has been discovered and the region/residue responsible for its activity identified using an evolutionary approach. Furthermore, IFI16, an innate immunity protein known to sense several viruses, has been shown to contribute to the defense to HIV-1 by causing cell death upon sensing HIV-1 DNA. Restriction factors against HIV show characteristic signatures of positive selection. Different patterns of accelerated sequence evolution can distinguish antiviral strategies--offense or defence--as well as the level of specificity of the antiviral properties. Sequence analysis of primate orthologs of restriction factors serves to localize functional domains and sites responsible for antiviral action. We use recent discoveries to illustrate how evolutionary genomic analyses help identify new antiviral genes and their mechanisms of action.

Making evolutionary biology a basic science for medicine

Science.gov (United States)

Nesse, Randolph M.; Bergstrom, Carl T.; Ellison, Peter T.; Flier, Jeffrey S.; Gluckman, Peter; Govindaraju, Diddahally R.; Niethammer, Dietrich; Omenn, Gilbert S.; Perlman, Robert L.; Schwartz, Mark D.; Thomas, Mark G.; Stearns, Stephen C.; Valle, David

2010-01-01

New applications of evolutionary biology in medicine are being discovered at an accelerating rate, but few physicians have sufficient educational background to use them fully. This article summarizes suggestions from several groups that have considered how evolutionary biology can be useful in medicine, what physicians should learn about it, and when and how they should learn it. Our general conclusion is that evolutionary biology is a crucial basic science for medicine. In addition to looking at established evolutionary methods and topics, such as population genetics and pathogen evolution, we highlight questions about why natural selection leaves bodies vulnerable to disease. Knowledge about evolution provides physicians with an integrative framework that links otherwise disparate bits of knowledge. It replaces the prevalent view of bodies as machines with a biological view of bodies shaped by evolutionary processes. Like other basic sciences, evolutionary biology needs to be taught both before and during medical school. Most introductory biology courses are insufficient to establish competency in evolutionary biology. Premedical students need evolution courses, possibly ones that emphasize medically relevant aspects. In medical school, evolutionary biology should be taught as one of the basic medical sciences. This will require a course that reviews basic principles and specific medical applications, followed by an integrated presentation of evolutionary aspects that apply to each disease and organ system. Evolutionary biology is not just another topic vying for inclusion in the curriculum; it is an essential foundation for a biological understanding of health and disease. PMID:19918069

Fughe ‘dal’ tempo, fughe ‘nel’ tempo: Borges, McTaggart, Nabokov

Directory of Open Access Journals (Sweden)

Francesco Baucia

2014-10-01

Full Text Available Questo intervento presenta due diversi tipi di rapporto tra i concetti di ‘fuga’ e di ‘temporalità’, che sono esemplificati da due frasi tratte da una coppia di opere di V. Nabokov. Il primo tipo di rapporto esaminato può essere chiamato ‘fuga dal tempo’: si tratta di una relazione tra questi concetti che rivela una posizione filosofica scettica nei confronti dell’esistenza reale del tempo, posizione che è condivisa da scrittori come J.L. Borges e da filosofi come J.T. McTaggart. Il secondo tipo di rapporto può essere invece denominato ‘fuga nel tempo’: secondo Nabokov, la temporalità è la dimensione più decisiva per l’arte e la letteratura, e dunque non è possibile realizzare una ‘vera’ fuga dal tempo. Il vero obiettivo dell’artista deve essere pertanto quello di realizzare una fuga nell’elemento puro (medium della temporalità, ossia nella sua ‘tessitura’, piuttosto che nei suoi contenuti (nel suo ‘testo’.

Heart rate responses induced by acoustic tempo and its interaction with basal heart rate.

Science.gov (United States)

Watanabe, Ken; Ooishi, Yuuki; Kashino, Makio

2017-03-07

Many studies have revealed the influences of music on the autonomic nervous system (ANS). Since previous studies focused on the effects of acoustic tempo on the ANS, and humans have their own physiological oscillations such as the heart rate (HR), the effects of acoustic tempo might depend on the HR. Here we show the relationship between HR elevation induced by acoustic tempo and individual basal HR. Since high tempo-induced HR elevation requires fast respiration, which is based on sympatho-respiratory coupling, we controlled the participants' respiration at a faster rate (20 CPM) than usual (15 CPM). We found that sound stimuli with a faster tempo than the individual basal HR increased the HR. However, the HR increased following a gradual increase in the acoustic tempo only when the extent of the gradual increase in tempo was within a specific range (around + 2%/min). The HR did not follow the increase in acoustic tempo when the rate of the increase in the acoustic tempo exceeded 3% per minute. These results suggest that the effect of the sympatho-respiratory coupling underlying the HR elevation caused by a high acoustic tempo depends on the basal HR, and the strength and the temporal dynamics of the tempo.

Structure and properties of tempo-oxidized cotton fibers

Directory of Open Access Journals (Sweden)

Milanovic Jovana

2012-01-01

Full Text Available In this paper, the influence of the catalytic oxidation using water soluble and stable nitroxyl radical 2,2´,6,6´-tetramethylpiperidine-1-oxyl (TEMPO on structure and properties of cotton fibers was studied. In particular, the selective TEMPO-mediated oxidation has become very interesting way for introduction of functional groups into cellulose fibers with the aim to obtain oxycellulose fibers with specific properties. Unmodified and modified fibers were characterized in terms of weight loss values, introduced functional groups and crystallinity index. Also, oxidized fibers were characterized in terms of the sorption, morphological, and physico-mechanical properties. The TEMPO-oxidized cotton fibers show a minimum increase of fineness (from 1.32 to 1.28 dtex and increase of crystallinity index (up to 91.9%, while the tensile strength of fibers decreases (up to 10.82 cN/tex. By the TEMPO-mediated oxidation of cotton fibers significant amount of carboxyl groups (up to 0.795 mmol/g cell can be introduced into cellulose fibers. Introduced hydrophilic carboxyl groups increases the sorption properties of oxidized fibers, that can be used directly or for further chemical modification.

Spatial effect on stochastic dynamics of bistable evolutionary games

International Nuclear Information System (INIS)

So, Kohaku H Z; Ohtsuki, Hisashi; Kato, Takeo

2014-01-01

We consider the lifetimes of metastable states in bistable evolutionary games (coordination games), and examine how they are affected by spatial structure. A semiclassical approximation based on a path integral method is applied to stochastic evolutionary game dynamics with and without spatial structure, and the lifetimes of the metastable states are evaluated. It is shown that the population dependence of the lifetimes is qualitatively different in these two models. Our result indicates that spatial structure can accelerate the transitions between metastable states. (paper)

Influencia del tempo de la música en las emociones

Directory of Open Access Journals (Sweden)

Jonathan Azael Caballero-Meneses

2010-01-01

exposición de 24 estudiantes de licenciatura a treinta extractos musicales de distinto tempo. Además se evaluó la posible modulación de la relación tempo-valencia por el rasgo de personalidad extroversión/introversión. Los resultados confirmaron la influencia del tempo sobre el arousal, pero no sobre la valencia, así como una posible mediación de la dimensión de personalidad introversión-extroversión sobre la valencia.

The Effect of Repetition on Tempo Preferences of Elementary Children.

Science.gov (United States)

Moskovitz, Elisa M.

1992-01-01

Reports on a study of children's preferences between slow and fast tempo classical music excerpts. Finds that students preferred music with a slow tempo. Concludes that repetition had a positive effect on children's preferences. (CFR)

Twin-peak effect in both cardiac response and tempo of popular music.

Science.gov (United States)

Shih, Yi-Sen; Zhang, Wen-Chih; Lee, Yaw-Chern; Lei, Chun-Yang; Tseng, Cheng-Lung; Wang, Hui-Min; Huang, Sheng-Chieh

2011-01-01

How the musical tempo affects the performance of heart rate variability (HRV) was studied in this work. By understanding the relationship between the HRV response and the music tempo with decreasing tempo from 140 to 70 beats per minute (bpm) periodically in six successive weeks. There were two groups in the experiment, one was listening drum loop music 3 minutes in the middle of experiment and the other was just rest for 20 minutes. After the processed the information from the objects, the distribution of difference of HRV response between before and after listening various tempo drum loop was similar to the distribution of modern popular music in tempo. Both distributions have the twin peaks about 70-85 and 110-125 bpm.

O tempo da escola: organização, ampliação e qualificação do tempo do ensino escolar

Directory of Open Access Journals (Sweden)

Antonio Chizzotti

2016-12-01

Full Text Available Este artigo analisa a organização administrativa e pedagógica do tempo escolar e avalia as discussões sobre a ampliação da jornada escolar e a qualificação desse tempo dispendido no ensino com a finalidade de criar melhores condições de aprendizagem e de bem-estar para todos os que estão comprometidos com a vida da escola. O texto levanta algumas controvérsias e iniciativas internacionais, que buscam encontrar alternativas para promover uma disposição mais adequada desse ritmo do tempo a fim de propiciar melhores condições do sucesso no ensino e de qualidade na duração da jornada escolar. O entendimento metodológico deste trabalho de conformidade com Gaussel (2013 pressupõe o reconhecimento de uma pluralidade de tempos educativos e múltiplos modos legítimos de aprendizagem e ensino. Toma-se o calendário como modelo de organização e gerenciamento das atividades escolares, e de observações e contatos pessoais com os atores educacionais em uma escola, para levantar algumas considerações críticas sobre a disposição do ritmo do tempo escolar a partir da análise do calendário de uma escola pública do Ensino Médio do sistema de ensino do Estado de São Paulo.

Analisi e variazioni di tempo: la Polacca op. 53 di Chopin

Directory of Open Access Journals (Sweden)

Giorgio Sanguinetti

2013-12-01

Full Text Available L'aspetto più difficile e sfuggente dell'esecuzione musicale è forse quello della scelta del tempo e delle sue variazioni. Qual è il tempo giusto per una composizione, e come va stabilito? E poi, una volta deciso il tempo generale, questo va osservato strettamente o l'esecutore può concedersi accelerandi e rallentandi occasionali, o addirittura cambiare il tempo in una data parte della composizione, per poi riprendere successivamente il tempo principale? In cosa consiste il rubato, e dove questa pratica trova legittimità? È giustificato introdurre una variazione agogica anche dove il compositore non l'ha prescritta? Domande di questo genere si pongono continuamente agli esecutori, e le risposte ovviamente dipendono da una gran quantità di fattori, prima di tutto dal contesto storico e stilistico nel quale il pezzo è originato, e dalla conoscenza della prassi esecutiva relativa alla sua epoca e alla sua tradizione locale.

TEMPO-based catholyte for high-energy density nonaqueous redox flow batteries.

Science.gov (United States)

Wei, Xiaoliang; Xu, Wu; Vijayakumar, Murugesan; Cosimbescu, Lelia; Liu, Tianbiao; Sprenkle, Vincent; Wang, Wei

2014-12-03

A TEMPO-based non-aqueous electrolyte with the TEMPO concentration as high as 2.0 m is demonstrated as a high-energy-density catholyte for redox flow battery applications. With a hybrid anode, Li|TEMPO flow cells using this electrolyte deliver an energy efficiency of ca. 70% and an impressively high energy density of 126 W h L(-1) . © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Tempo effects in mortality: An appraisal

Directory of Open Access Journals (Sweden)

Michel Guillot

2006-01-01

Full Text Available This study examines the existence of tempo effects in mortality and evaluates the procedure developed by Bongaarts and Feeney for calculating a tempo-adjusted life expectancy. It is shown that Bongaarts and Feeney's index can be interpreted as an indicator reflecting current mortality conditions under specific assumptions regarding the effects of changing period mortality conditions on the timing of future cohort deaths. It is argued, however, that currently there is no clear evidence about the existence of such effects in actual populations. This paper concludes that until the existence of these effects can be demonstrated, it is preferable to continue using the conventional life expectancy as an indicator of current mortality conditions.

catalysed selective oxidation of benzyl alcohols using TEMPO and ...

Indian Academy of Sciences (India)

A general scheme for the oxidation of benzyl alcohols catalyzed by silica functionalized copper (II) has been designed. TEMPO, a free radical, assists this oxidation that was initiated by molecular oxygen which converts it to a primary oxidant. This catalytic combination i.e. SiO2 -Cu(II) in presence of TEMPO and oxygen ...

Quality management of cut carnation 'Tempo' with 1- MCP | Abadi ...

African Journals Online (AJOL)

Quality management of cut carnation 'Tempo' with 1- MCP. ... African Journal of Biotechnology ... time durations (3, 6 and 9 h) on the vaselife, water uptake, loss of fresh weight and chlorophyll index of cut carnation 'Tempo' which is an ...

Memory for musical tempo: Additional evidence that auditory memory is absolute

OpenAIRE

Levitin, Daniel J.; Cook, Perry R.

1996-01-01

We report evidence that long term memory retains absolute (accurate) features of perceptual events. Specifically, we show that memory for music seems to preserve the absolute tempo of the musical performance. In Experiment 1, 46 subjects sang popular songs from memory, and their tempos were compared to recorded versions of the songs. Seventy-two of the subjects came within 8% of the actual tempo on two consecutive trials (using different songs), demonstrating accuracy near the perceptual thre...

INFLUENCIA DEL TEMPO DE LA MÚSICA EN LAS EMOCIONES

OpenAIRE

Jonathan Azael Caballero-Meneses; Marina Menez

2010-01-01

Se sabe que la música puede influir en dos componentes de las emociones: el arousal y la valencia. En particular, se ha reportado que el tempo o rapidez de la música está directamente relacionado con el arousal, aunque su relación con la valencia o medida de afecto no es aún clara. En este trabajo se analizó la influencia del tempo en ambos componentes mediante la exposición de 24 estudiantes de licenciatura a treinta extractos musicales de distinto tempo. Además se evaluó la posible m...

A ADMINISTRAÇÃO DO TEMPO LIVRE

OpenAIRE

Musse, Ricardo

2016-01-01

Resumo A conferência de Theodor W. Adorno sobre o conceito e a prática do "tempo livre", publicada em Stichworte, em 1969, foi proferida numa época de pleno emprego. A gradativa redução da jornada normal de trabalho, sinalizando e consolidando uma tendência de longo prazo, inspirou uma série de conjecturas acerca de uma possível mudança nas estruturas até então assentadas como próprias do mundo moderno. Nesse contexto, a conferência-ensaio de Adorno organiza-se, ao mesmo tempo, como uma atual...

Thermosetting polymer for dynamic nuclear polarization: Solidification of an epoxy resin mixture including TEMPO

Energy Technology Data Exchange (ETDEWEB)

Noda, Yohei, E-mail: noda.yohei@jaea.go.jp [Quantum Beam Science Centre, Sector of Nuclear Science Research, Japan Atomic Energy Agency, Shirakata-Shirane, Tokai, Ibaraki 319-1195 (Japan); Kumada, Takayuki [Quantum Beam Science Centre, Sector of Nuclear Science Research, Kansai Photon Science Institute, Japan Atomic Energy Agency, Kizugawa, Kyoto 619-0215 (Japan); Yamaguchi, Daisuke; Shamoto, Shin-ichi [Quantum Beam Science Centre, Sector of Nuclear Science Research, Japan Atomic Energy Agency, Shirakata-Shirane, Tokai, Ibaraki 319-1195 (Japan)

2015-03-11

We investigated the dynamic nuclear polarization (DNP) of typical thermosetting polymers (two-component type epoxy resins; Araldite{sup ®} Standard or Araldite{sup ®} Rapid) doped with a (2,2,6,6-tetramethylpiperidine-1-yl)oxy (TEMPO) radical. The doping process was developed by carefully considering the decomposition of TEMPO during the solidification of the epoxy resin. The TEMPO electron spin in each two-component paste decayed slowly, which was favorable for our study. Furthermore, despite the dissolved TEMPO, the mixture of the two-component paste successfully solidified. With the resulting TEMPO-doped epoxy-resin samples, DNP experiments at 1.2 K and 3.35 T indicated a magnitude of a proton-spin polarization up to 39%. This polarization is similar to that (35%) obtained for TEMPO-doped polystyrene (PS), which is often used as a standard sample for DNP. To combine this solidification of TEMPO-including mixture with a resin-casting technique enables a creation of polymeric target materials with a precise and complex structure.

Interaction with Mass Media: The Importance of Rhythm and Tempo.

Science.gov (United States)

Snow, Robert P.

1987-01-01

Stresses that understanding the impact of interaction with mass media requires conceptualizing media as an institutionalized social form. A critical feature of this process is the grammatical character of media interaction in the form of rhythm and tempo, because these rhythms and tempos become established in everyday routine. (SKC)

Tempo máximo de fonação /a/, tempo máximo de fonação previsto e tipo respiratório de mulheres adultas sem afecções laríngeas

Directory of Open Access Journals (Sweden)

Carla Aparecida Cielo

2015-04-01

Full Text Available OBJETIVO:verificar a diferença entre o tempo máximo de fonação /a/ e tempo máximo de fonação previsto em relação ao tipo respiratório, e correlacionar os tempos máximos em mulheres adultas com capacidade vital dentro da normalidade e sem afecções laríngeas.MÉTODOS:pesquisa transversal analítica, quantitativa e retrospectiva, em banco de dados, de 51 sujeitos do sexo feminino, com diagnóstico otorrinolaringológico de ausência de afecção laríngea, com idades entre 18 e 44 anos (média 27,64. Utilizaram-se os dados: maior valor de tempo máximo de fonação de /a/, tempo máximo de fonação previsto, capacidade vital e tipo respiratório. O valor do tempo máximo previsto para mulheres foi calculado multiplicando-se a capacidade vital por 0,0051, e o valor encontrado foi determinante para a classificação do tempo de /a/ em normal, abaixo ou acima do previsto.RESULTADOS:houve diferença significante entre tempo de fonação previsto e os tipos respiratórios superior (17,44s e misto (15,17s. Não houve diferença significante do tempo máximo de fonação /a/ nos diferentes tipos respiratórios, nem correlação entre tempo de fonação /a/ e tempo previsto.CONCLUSÃO:não houve correlação entre tempo de /a/ e tempo de fonação previsto e este último foi significantemente maior no tipo respiratório superior do que no misto na população estudada.

Particle Filtering Applied to Musical Tempo Tracking

Directory of Open Access Journals (Sweden)

Macleod Malcolm D

2004-01-01

Full Text Available This paper explores the use of particle filters for beat tracking in musical audio examples. The aim is to estimate the time-varying tempo process and to find the time locations of beats, as defined by human perception. Two alternative algorithms are presented, one which performs Rao-Blackwellisation to produce an almost deterministic formulation while the second is a formulation which models tempo as a Brownian motion process. The algorithms have been tested on a large and varied database of examples and results are comparable with the current state of the art. The deterministic algorithm gives the better performance of the two algorithms.

MUSIC TEMPO'S EFFECT ON EXERCISE PERFORMANCE: COMMENT ON DYER AND McKUNE.

Science.gov (United States)

Nakamura, Priscila Missaki

2015-06-01

Dyer and McKune (2013) stated that music tempo has no influence on performance, physiological, and psychophysical variables in well-trained cyclists during high intensity endurance tasks. However, there are important limitations in the methodology of the study. The participants' music preferences and tempo change were not well measured. It is not possible to affirm that music tempo does not influence athletes' performance. Potential areas of future research include: (a) use of instruments to assess the qualities of music; (b) standardizing music of tempo according to exercise type (e.g., running, cycling, etc.); (c) considering training level of the participants (i.e., athletes and non-athletes); and (d) use of instruments to assess concentration during exercise.

Cellulose Nanocomposites by Melt Compounding of TEMPO-Treated Wood Fibers in Thermoplastic Starch Matrix

Directory of Open Access Journals (Sweden)

Aline Cobut

2014-04-01

Full Text Available To facilitate melt compounding of cellulose nanofibrils (CNF based composites, wood pulp fibers were subjected to a chemical treatment whereby the fibers were oxidized using 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO. This treatment introduced negatively charged carboxylate groups to the fibers. TEMPO-treated fibers (TempoF were added to a mixture of amylopectin starch, glycerol, and water. Granules were prepared from this mixture and processed into CNF composites by extrusion. TempoF were easier to process into composites as compared with non-treated pulp fibers (PF. SEM revealed partial disintegration of TempoF during melt processing. Consequently, TempoF gave composites with much better mechanical properties than those of conventional composites prepared from pulp fibers and TPS. Particularly, at 20 wt% TempoF content in the composite, the modulus and strength were much improved. Such a continuous melt processing route, as an alternative to laboratory solvent casting techniques, may promote large-scale production of CNF-based composites as an environmentally friendly alternative to synthetic plastics/composites.

The rhythm and tempo of the game of highly qualified teams

Directory of Open Access Journals (Sweden)

V’yacheslav Mulik

2015-06-01

Full Text Available Purpose: to set indicators of rhythm and tempo of the game teams of high qualification. Material and Methods: analysis of the scientific-methodical literature, registration of technical-tactical actions, methods of mathematical statistics. The study of competitive activities was conducted with participating teams of world championship 2014. Results: the acticle shows indicators of the rhythm and tempo of the game of well-qualified teams. Conclusions: teams-winners have surpassed teams that concede in terms of indicators of passes the ball, shots at goal, the rhythm of the game, tempo of game.

Music genre preference and tempo alter alpha and beta waves in human non-musicians

Directory of Open Access Journals (Sweden)

Hunter Gentry

2013-10-01

Full Text Available This study examined the effects of music genre and tempo on brain activation patterns in 10 nonmusicians.Two genres (rock and jazz and three tempos (slowed, medium/normal, andquickened were examined using EEG recording and analyzed through Fast Fourier Transform(FFT analysis. When participants listened to their preferred genre, an increase in alpha waveamplitude was observed. Alpha waves were not significantly affected by tempo. Beta waveamplitude increased significantly as the tempo increased. Genre had no effect on beta waves. Thefindings of this study indicate that genre preference and artificially modified tempo do affectalpha and beta wave activation in non-musicians listening to preselected songs.

Does the Tempo of Music Impact Human Behavior Behind the Wheel?

Science.gov (United States)

Navarro, Jordan; Osiurak, François; Reynaud, Emanuelle

2018-06-01

Assess the influence of background music tempo on driving performance. Music with a fast tempo is known to increase the level of arousal, whereas the reverse is observed for slow music. The relationship between driving performance and level of arousal was expected to take the form of an inverted U-curve. Three experiments were undertaken to manipulate the musical background during driving. In Experiment 1, the driver's preferred music track played at its original and modified (plus or minus 30%) tempo were used together with the simple ticking of a metronome. In Experiment 2, music tracks of different tempos were played during driving. In Experiment 3, music tracks were categorized as arousing or relaxing based on the associated perceived level of arousal. Listening to music tended to influence drivers' performances in a car-following task by improving coherence and gain adjustments relative to the followed vehicle but simultaneously shortened the intervehicular time. Although the tempo of the music per se did not directly affect driving behavior, arousing music tracks improved drivers' adjustments to the followed vehicle (Experiment 3). The tempo of the music listened to behind the wheel was not found to influence driving behaviors. However, arousing music improved drivers' responsiveness to changes in the speed of the followed vehicle. However, this benefit was canceled out by a reduction in the drivers' intervehicle safety margin. Listening to arousing music while driving cannot be considered to improve road safety, at least in a car-following task without attentional impairments.

Tempo and mode in the macroevolutionary reconstruction of Darwinism.

Science.gov (United States)

Gould, S J

1994-01-01

Among the several central meanings of Darwinism, his version of Lyellian uniformitarianism--the extrapolationist commitment to viewing causes of small-scale, observable change in modern populations as the complete source, by smooth extension through geological time, of all magnitudes and sequences in evolution--has most contributed to the causal hegemony of microevolution and the assumption that paleontology can document the contingent history of life but cannot act as a domain of novel evolutionary theory. G. G. Simpson tried to combat this view of paleontology as theoretically inert in his classic work, Tempo and Mode in Evolution (1944), with a brilliant argument that the two subjects of his title fall into a unique paleontological domain and that modes (processes and causes) can be inferred from the quantitative study of tempos (pattern). Nonetheless, Simpson did not cash out his insight to paleontology's theoretical benefit because he followed the strict doctrine of the Modern Synthesis. He studied his domain of potential theory and concluded that no actual theory could be found--and that a full account of causes could therefore be located in the microevolutionary realm after all. I argue that Simpson was unduly pessimistic and that modernism's belief in reductionistic unification (the conventional view of Western intellectuals from the 1920s to the 1950s) needs to be supplanted by a postmodernist commitment to pluralism and multiple levels of causation. Macro- and microevolution should not be viewed as opposed, but as truly complementary. I describe the two major domains where a helpful macroevolutionary theory may be sought--unsmooth causal boundaries between levels (as illustrated by punctuated equilibrium and mass extinction) and hierarchical expansion of the theory of natural selection to levels both below (gene and cell-line) and above organisms (demes, species, and clades). Problems remain in operationally defining selection at non-organismic levels

Effects of lifting tempo on one repetition maximum and hormonal responses to a bench press protocol.

Science.gov (United States)

Headley, Samuel A; Henry, Kelley; Nindl, Bradley C; Thompson, Brian A; Kraemer, William J; Jones, Margaret T

2011-02-01

This study was carried out in 2 parts: part 1 was designed to measure the 1 repetition maximum (1RM) bench press with 2 different moderate-velocity tempos (2/0/2) vs. (2/0/4) in male lifters while part 2 compared the hormonal responses at the same tempos as described in part 1. In both parts 1 and 2, the 1RMs (lbs) were higher on the 2/0/2 tempo than on the 2/0/4 tempo. The change in plasma volume (PV) was greater after the 2/0/4 tempo (-5.7 ± 1.7% vs. 0.96 ± 1.2%, p < 0.05). All blood parameters were significantly (p < 0.05) higher post-exercise compared with baseline. With PV corrected, insulin-like growth factor 1 (IGF-1) (ng·mL⁻¹) was higher with the 2/0/2 tempo only (pre-exercise: 277.4 ± 21.8, post-exercise: 308.1 ± 22.9; 2/0/4 tempo pre-exercise: 277.2 ± 17.6, post-exercise: 284.8 ± 21.2). In conclusion, heavier loads can be lifted and more total work can be performed using a (2/0/2) tempo compared with a slower (2/0/4) tempo, but with the exception of IGF-1, the hormonal responses are similar. Individuals may get the same metabolic responses to training by using different tempos, but they will need to use less weight at a slower tempo.

Robust data reconciliation with TEMPO

International Nuclear Information System (INIS)

Sunde, Svein; Banati, Jozsef

2004-03-01

The Halden Project's TEMPO system is devised to meet the increasing challenges facing utilities in performance monitoring and optimisation, among other things due to deregulation and market liberalisation. The data reconciliation mode is an important one in the TEMPO system. Data reconciliation is a method to provide reliable estimates of process states, parameters, the state of equipment and instruments, and efficiency. Data reconciliation follows maximum likelihood principles, and is usually based on a Gaussian error model for the data. Data reconciliation thus estimates the most likely state of the process, given the heat and mass balance and the current instrument readings. If the assumption of normally (Gaussian) distributed errors in the measurements break down, as it will in the case of gross errors (outliers) in the data set, this needs to be detected by the monitoring system. TEMPO does this by computing an overall test statistic subjected to a hypothesis test, resulting in the so-called goodness-of-fit. If the goodness-of-fit takes a too low value, a fault is probably present in the process. Identifying the location of the fault is more difficult, however. With the Gaussian error model this is still possible employing a so-called serial elimination method. The serial elimination method is, however, cumbersome to use and leads to quite lengthy calculations. The present report describes the application of alternative distributions in the maximum likelihood estimation in an attempt to directly identify the location of faulty sensors. For direct identification of sensor faults significant improvements over the method based on a Gaussian error model has been achieved. However, serial elimination still leads to the highest success rate for fault identification. All results were based on Monte Carlo simulations. (Author)

Speed on the dance floor: Auditory and visual cues for musical tempo.

Science.gov (United States)

London, Justin; Burger, Birgitta; Thompson, Marc; Toiviainen, Petri

2016-02-01

Musical tempo is most strongly associated with the rate of the beat or "tactus," which may be defined as the most prominent rhythmic periodicity present in the music, typically in a range of 1.67-2 Hz. However, other factors such as rhythmic density, mean rhythmic inter-onset interval, metrical (accentual) structure, and rhythmic complexity can affect perceived tempo (Drake, Gros, & Penel, 1999; London, 2011 Drake, Gros, & Penel, 1999; London, 2011). Visual information can also give rise to a perceived beat/tempo (Iversen, et al., 2015), and auditory and visual temporal cues can interact and mutually influence each other (Soto-Faraco & Kingstone, 2004; Spence, 2015). A five-part experiment was performed to assess the integration of auditory and visual information in judgments of musical tempo. Participants rated the speed of six classic R&B songs on a seven point scale while observing an animated figure dancing to them. Participants were presented with original and time-stretched (±5%) versions of each song in audio-only, audio+video (A+V), and video-only conditions. In some videos the animations were of spontaneous movements to the different time-stretched versions of each song, and in other videos the animations were of "vigorous" versus "relaxed" interpretations of the same auditory stimulus. Two main results were observed. First, in all conditions with audio, even though participants were able to correctly rank the original vs. time-stretched versions of each song, a song-specific tempo-anchoring effect was observed, such that sped-up versions of slower songs were judged to be faster than slowed-down versions of faster songs, even when their objective beat rates were the same. Second, when viewing a vigorous dancing figure in the A+V condition, participants gave faster tempo ratings than from the audio alone or when viewing the same audio with a relaxed dancing figure. The implications of this illusory tempo percept for cross-modal sensory integration and

[Evolutionary medicine: an introduction. Evolutionary biology, a missing element in medical teaching].

Science.gov (United States)

Swynghedauw, Bernard

2009-05-01

The aim of this brief review article is to help to reconcile medicine with evolutionary biology, a subject that should be taught in medical school. Evolutionary medicine takes the view that contemporary ills are related to an incompatibility between the environment in which humans currently live and their genomes, which have been shaped by diferent environmental conditions during biological evolution. Human activity has recently induced acute environmental modifications that have profoundly changed the medical landscape. Evolutionary biology is an irreversible, ongoing and discontinuous process characterized by periods of stasis followed by accelerations. Evolutionary biology is determined by genetic mutations, which are selected either by Darwinian selective pressure or randomly by genetic drift. Most medical events result from a genome/environment conflict. Some may be purely genetic, as in monogenic diseases, and others purely environmental, such as traffic accidents. Nevertheless, in most common diseases the clinical landscape is determined by the conflict between these two factors, the genetic elements of which are gradually being unraveled Three examples are examined in depth:--The medical consequences of the greenhouse effect. The absence of excess mortality during recent heat waves suggests that the main determinant of mortality in the 2003 heatwave was heatstroke and old age. The projected long-term effects of global warming call for research on thermolysis, a forgotten branch of physiology.--The hygiene hypothesis postulates that the exponential rise in autoimmune and allergic diseases is linked to lesser exposure to infectious agents, possibly involving counter-regulatory factors such as IL-10.--The recent rise in the incidence of obesity and type 2 diabetes in rich countries can be considered to result from a conflict between a calorie-rich environment and gene variants that control appetite. These variants are currently being identified by genome

FERTILITY INTENTIONS AND EARLY LIFE HEALTH STRESS AMONG WOMEN IN EIGHT INDIAN CITIES: TESTING THE REPRODUCTIVE ACCELERATION HYPOTHESIS.

Science.gov (United States)

Kulathinal, Sangita; Säävälä, Minna

2015-09-01

In life history theory, early life adversity is associated with an accelerated reproductive tempo. In harsh and unpredictable conditions in developing societies fertility is generally higher and the reproductive tempo faster than in more secure environments. This paper examines whether differences in female anthropometry, particularly adult height, are associated with fertility intentions of women in urban environments in India. The study population consists of women aged 15-29 (N=4485) in slums and non-slums of eight Indian cities in the National Family Health Survey (NFHS) of 2005-2006. Adult height is taken as a proxy for early childhood health and nutritional condition. Fertility intentions are examined by using two variables: the desire to have a child or another child, and to have it relatively soon, as indicative of accelerated reproductive scheduling. Evidence supporting the acceleration hypothesis is found in two urban frames out of 26 examined in a two-staged multinomial logistic model. In three cases, the relationship between fertility intentions and height is the opposite than expected by the acceleration hypothesis: taller women have a higher predictive probability of desiring a(nother) child and/or narrower birth spacing. Potential explanations for the partly contradictory relationship between the childhood health indicator and fertility intentions are discussed.

‘Tempo é dinheiro’: Usabilidade é Produtividade

Directory of Open Access Journals (Sweden)

Antonio Mendes Silva Filho

2012-09-01

Full Text Available Benjamin Franklin foi um intelectual de sua época (1706-1790 e uma frase marcante dele que ultrapassa fronteiras é “Remember that time is money”. Lembre-se do que já disse: Tempo é o bem mais precioso que todo ser humano pode possuir, inclusive para aqueles que pensam nada ter. Tempo impacta a produtividade, tema esse explorado neste artigo que se concentra em discutir como a facilidade em realizar atividades utilizando tablets, smartphones, computadores e outros artefatos podem impactar a produtividade. Essa ‘facilidade em realizar atividades’ é denominada de usabilidade e, sesse sentido, este artigo explora como a inspeção por meio da análise e interpretação de dados podem auxiliar nessa tarefa.

Role of tempo entrainment in psychophysiological differentiation of happy and sad music?

Science.gov (United States)

Khalfa, Stéphanie; Roy, Mathieu; Rainville, Pierre; Dalla Bella, Simone; Peretz, Isabelle

2008-04-01

Respiration rate allows to differentiate between happy and sad excerpts which may be attributable to entrainment of respiration to the rhythm or the tempo rather than to emotions [Etzel, J.A., Johnsen, E.L., Dickerson, J., Tranel, D., Adolphs, R., 2006. Cardiovascular and respiratory responses during musical mood induction. Int. J. Psychophysiol. 61(1), 57-69]. In order to test for this hypothesis, this study intended to verify whether fast and slow rhythm, and/or tempo alone are sufficient to induce differential physiological effects. Psychophysiological responses (electrodermal responses, facial muscles activity, blood pressure, heart and respiration rate) were then measured in fifty young adults listening to fast/happy and slow/sad music, and to two control versions of these excerpts created by removing pitch variations (rhythmic version) and both pitch and temporal variations (beat-alone). The results indicate that happy and sad music are significantly differentiated (happy>sad) by diastolic blood pressure, electrodermal activity, and zygomatic activity, while the fast and slow rhythmic and tempo control versions did not elicit such differentiations. In contrast, respiration rate was faster with stimuli presented at fast tempi relative to slow stimuli in the beat-alone condition. It was thus demonstrated that the psychophysiological happy/sad distinction requires the tonal variations and cannot be explained solely by entrainment to tempo and rhythm. The tempo entrainment exists in the tempo alone condition but our results suggest this effect may disappear when embedded in music or with rhythm.

Long-term memory for music: infants remember tempo and timbre.

Science.gov (United States)

Trainor, Laurel J; Wu, Luann; Tsang, Christine D

2004-06-01

We show that infants' long-term memory representations for melodies are not just reduced to the structural features of relative pitches and durations, but contain surface or performance tempo- and timbre-specific information. Using a head turn preference procedure, we found that after a one week exposure to an old English folk song, infants preferred to listen to a novel folk song, indicating that they remembered the familiarized melody. However, if the tempo (25% faster or slower) or instrument timbre (harp vs. piano) of the familiarized melody was changed at test, infants showed no preference, indicating that they remembered the specific tempo and timbre of the melodies. The results are consistent with an exemplar-based model of memory in infancy rather than one in which structural features are extracted and performance features forgotten.

Tempos escolares e tempos de vida: (repensando práticas pedagógicas da EJA na contemporaneidade

Directory of Open Access Journals (Sweden)

Eufrázia Nenê Miranda

2017-08-01

Full Text Available As práticas estão desconsiderando os tempos de vida dos alunos. Isso está provocando uma crise na escola contemporânea, afetando a ordem dos discursos que, historicamente detém-se, tão somente, ao currículo, desconsiderando os tempos de vida dos sujeitos. Desse modo, não é sobre o produto do conhecimento que se deve recair o foco das discussões curriculares, mas sobre os processos de construção e consideração dos tempos escolares no currículo da EJA. Assim, ao longo do presente artigo, reforçaremos que as construções temporais melhor se desenvolvem e se estabilizam quando estas são afirmadas como resultado da interseção de políticas públicas e de práticas escolares, estruturando-o da seguinte forma: Iniciaremos com tema: Adultos Jovens – Jovens Alunos: uma relação transversal com o tempo, que trará alguns esclarecimentos acerca dos conceitos de adulto, jovem e sua relação com o tempo. Bem como, alguns tópicos relevantes sobre Currículo, Escola e Aluno. Em tempo, traremos algumas inferências a respeito dos tempos sombreados nos discursos escolares e, finalizaremos com uma análise, resultado do trabalho de campo se desenrolou entre junho 2014 a agosto de 2015, com visitas periódicas à unidade escolar NEEJA3. O trabalho de campo mesclou instrumentos de investigação (entrevistas e observações ligados às diversas dimensões constituintes do tempo escolar, que envolveram alunos das totalidades sete, oito e nove, que equivalem a séries fi nais do Ensino Médio, que estimou escores para tal. Palavras – chave: EJA. Currículo. Tempo School times and lifetimes: (re thinking pedagogical practices of the EJA in contemporary times ABSTRACT The practices are disregarding the lives of students times. This is causing a crisis in contemporary school, affecting the order of speeches that historically dwells, alone, to the curriculum, disregarding the lifetimes of subjects. Thus, it is not about the product knowledge

Susceptibility of Iα- and Iβ-Dominated Cellulose to TEMPO-Mediated Oxidation.

Science.gov (United States)

Carlsson, Daniel O; Lindh, Jonas; Strømme, Maria; Mihranyan, Albert

2015-05-11

The susceptibility of Iα- and Iβ-dominated cellulose to TEMPO-mediated oxidation was studied in this work since the cellulose Iα-allomorph is generally considered to be thermodynamically less stable and therefore more reactive than the cellulose Iβ-allomorph. Highly crystalline Cladophora nanocellulose, which is dominated by the Iα-allomorph, was oxidized to various degrees with TEMPO oxidant via bulk electrolysis in the absence of co-oxidants. Further, the Cladophora nanocellulose was thermally annealed in glycerol to produce its Iβ-dominated form and then oxidized. The produced materials were subsequently studied using FTIR, CP/MAS (13)C NMR, XRD, and SEM. The solid-state analyses confirmed that the annealed Cladophora cellulose was successfully transformed from an Iα- to an Iβ-dominated form. The results of the analyses of pristine and annealed TEMPO-oxidized samples suggest that Iα- and Iβ-dominated cellulose do not differ in susceptibility to TEMPO-oxidation. This work hence suggests that cellulose from different sources are not expected to differ in susceptibility to the oxidation due to differences in allomorph composition.

Ricardo, o tempo e o valor

Directory of Open Access Journals (Sweden)

Rogério Arthmar

2014-03-01

Full Text Available O artigo revisa a evolução da teoria ricardiana do valor em sua conexão com o elemento tempo. Inicialmente, procede-se breve inspeção da primeira proposta de Ricardo para a lei geral das trocas. Contempla-se, a seguir, uma ilustração numérica da fórmula original dos preços competitivos, esclarecendo-se como o fator tempo surgiu nas discussões sobre a teoria desenvolvida nos Principles. Examina-se ainda a versão simplificada da regra do valor introduzida na terceira edição do livro, assim como a proposição ricardiana fundamental de que as variações nos lucros teriam impacto mínimo nos preços. Mostra-se, na última seção, que a generalização do exemplo concebido por Ricardo, incluindo processos produtivos com múltiplos períodos, não sustenta tal asserção.

Ratings of speed in real music as a function of both original and manipulated beat tempo.

Science.gov (United States)

Madison, Guy; Paulin, Johan

2010-11-01

There is an apparent contradiction between the narrow range of tempi optimal for perceptual judgment and motor synchronization and the wide range of beat tempi found in real music. The relation between listeners' perception of speed and beat tempo was therefore investigated, both for real music excerpts (ME) and metronome sequences. Tempi ranged from 42 to 200 beats per minute (BPM), and some excerpts were further tempo manipulated in four levels from ±5 to ±20%. Regression analyses showed that speed was a shallower function of original tempo for fast (>150 BPM) and slow (tempo had twice as large an effect on speed as had original tempo. In contrast, speed was an almost linear function of tempo for metronome sequences. Taken together, these results show that the non-linearity stems from properties of the musical signal, rather than being a subjective perceptual effect. They indicate an inverse relation between tempo and relative event density in real music, and demonstrate that the perception of periodic signals is affected not only by the beat level, but also by faster and slower levels.

Sensorimotor synchronization with tempo-changing auditory sequences: Modeling temporal adaptation and anticipation.

Science.gov (United States)

van der Steen, M C Marieke; Jacoby, Nori; Fairhurst, Merle T; Keller, Peter E

2015-11-11

The current study investigated the human ability to synchronize movements with event sequences containing continuous tempo changes. This capacity is evident, for example, in ensemble musicians who maintain precise interpersonal coordination while modulating the performance tempo for expressive purposes. Here we tested an ADaptation and Anticipation Model (ADAM) that was developed to account for such behavior by combining error correction processes (adaptation) with a predictive temporal extrapolation process (anticipation). While previous computational models of synchronization incorporate error correction, they do not account for prediction during tempo-changing behavior. The fit between behavioral data and computer simulations based on four versions of ADAM was assessed. These versions included a model with adaptation only, one in which adaptation and anticipation act in combination (error correction is applied on the basis of predicted tempo changes), and two models in which adaptation and anticipation were linked in a joint module that corrects for predicted discrepancies between the outcomes of adaptive and anticipatory processes. The behavioral experiment required participants to tap their finger in time with three auditory pacing sequences containing tempo changes that differed in the rate of change and the number of turning points. Behavioral results indicated that sensorimotor synchronization accuracy and precision, while generally high, decreased with increases in the rate of tempo change and number of turning points. Simulations and model-based parameter estimates showed that adaptation mechanisms alone could not fully explain the observed precision of sensorimotor synchronization. Including anticipation in the model increased the precision of simulated sensorimotor synchronization and improved the fit of model to behavioral data, especially when adaptation and anticipation mechanisms were linked via a joint module based on the notion of joint internal

The effects of music tempo and loudness level on treadmill exercise.

Science.gov (United States)

Edworthy, Judy; Waring, Hannah

2006-12-15

This study examined the effects of loudness and tempo of background music on exercise performance. A total of 30 volunteers performed five 10-min exercise sessions on a treadmill. The music listened to whilst exercising was either fast/loud, fast/quiet, slow/loud, slow/quiet or absent. Measures of running speed, heart rate, perceived exertion and affect were taken. Significant effects and interactions were found for running speed and heart rate across the different music tempo and loudness levels. More positive affect was observed during the music condition in comparison to the 'no music' condition. No significant differences for perceived exertion were found across conditions. These results confirm that fast, loud music might be played to enhance optimal exercising, and show how loudness and tempo interact.

Memory for surface features of unfamiliar melodies: independent effects of changes in pitch and tempo.

Science.gov (United States)

Schellenberg, E Glenn; Stalinski, Stephanie M; Marks, Bradley M

2014-01-01

A melody's identity is determined by relations between consecutive tones in terms of pitch and duration, whereas surface features (i.e., pitch level or key, tempo, and timbre) are irrelevant. Although surface features of highly familiar recordings are encoded into memory, little is known about listeners' mental representations of melodies heard once or twice. It is also unknown whether musical pitch is represented additively or interactively with temporal information. In two experiments, listeners heard unfamiliar melodies twice in an initial exposure phase. In a subsequent test phase, they heard the same (old) melodies interspersed with new melodies. Some of the old melodies were shifted in key, tempo, or key and tempo. Listeners' task was to rate how well they recognized each melody from the exposure phase while ignoring changes in key and tempo. Recognition ratings were higher for old melodies that stayed the same compared to those that were shifted in key or tempo, and detrimental effects of key and tempo changes were additive in between-subjects (Experiment 1) and within-subjects (Experiment 2) designs. The results confirm that surface features are remembered for melodies heard only twice. They also imply that key and tempo are processed and stored independently.

The tempo and mode of evolution: body sizes of island mammals.

Science.gov (United States)

Raia, Pasquale; Meiri, Shai

2011-07-01

The tempo and mode of body size evolution on islands are believed to be well known. It is thought that body size evolves relatively quickly on islands toward the mammalian modal value, thus generating extreme cases of size evolution and the island rule. Here, we tested both theories in a phylogenetically explicit context, by using two different species-level mammalian phylogenetic hypotheses limited to sister clades dichotomizing into an exclusively insular and an exclusively mainland daughter nodes. Taken as a whole, mammals were found to show a largely punctuational mode of size evolution. We found that, accounting for this, and regardless of the phylogeny used, size evolution on islands is no faster than on the continents. We compared different selection regimes using a set of Ornstein-Uhlenbeck models to examine the effects of insularity of the mode of evolution. The models strongly supported clade-specific selection regimes. Under this regime, however, an evolutionary model allowing insular species to evolve differently from their mainland relatives performs worse than a model that ignores insularity as a factor. Thus, insular taxa do not experience statistically different selection from their mainland relatives. © 2011 The Author(s). Evolution© 2011 The Society for the Study of Evolution.

Accelerating the culture change!

Science.gov (United States)

Klunk, S W; Panetta, J; Wooten, J

1996-11-01

Exide Electronics, a major supplier of uninterruptible power system equipment, embarked on a journey of changing a culture to improve quality, enhance customer responsiveness, and reduce costs. This case study examines the evolution of change over a period of seven years, with particular emphasis on the most recent years, 1992 through 1995. The article focuses on the Raleigh plant operations and describes how each succeeding year built on the successes and fixed the shortcomings of the prior years to accelerate the culture change, including corrective action and continuous improvement processes, organizational structures, expectations, goals, achievements, and pitfalls. The real challenge to changing the culture was structuring a dynamic approach to accelerate change! The presentation also examines how the evolutionary process itself can be created and accelerated through ongoing communication, regular feedback of progress and goals, constant evaluation and direction of the process, and measuring and paying for performance.

The thermal performance monitoring and optimisation system (TEMPO): lessons learnt

International Nuclear Information System (INIS)

Beere, W.H.Aa.

2005-09-01

The goal of condition monitoring, fault detection and diagnosis is to ensure the success of planned operations by recognizing anomalies in a plant. This is achieved by monitoring the condition of equipment and instrumentation, and by detection, identification, diagnosis and removal of faults. The method of using physical modelling for condition monitoring has been investigated at the Institutt for energiteknikk since 1998. The result of this work was the development of the TEMPO (ThErMal Performance monitoring and Optimisation) toolbox. In this toolbox plant wide models are built up of unit sub-models. These are then linked to measurements by using data reconciliation. This enables the comparison of calculated to measured values as well as an indication of the significance of any deviation. It also allows the calculation of unmeasured variables as well as an overall 'goodness of fit' indicator. Since its first release in 2000 the TEMPO toolbox has been used to model the turbine cycles of several NPPs. Installations include Forsmark 3 and Loviisa 2 with feasibility studies for Dukovany, Olkiluoto 2, Almaraz and Paks. The experience from creating and installing TEMPO at these plants has now been collated and is presented in this report. This experience is used to indicate which direction the further development of TEMPO should take. The experience of using TEMPO has shown that the data-reconciliation method can be applied to the turbine cycles of NPPs. Problems that have arose have primarily been connected to the usability of the toolbox. This has prompted a shift in the development emphasis from the task of developing the method to that of developing its usability. A summary of improvement proposals is given in this paper. The reader is welcome to comment on these proposals or to suggest alternative improvements. (Author)

Funzioni del tempo presente nella strategia narrativa

Directory of Open Access Journals (Sweden)

Aleksandra Koman

2017-08-01

Full Text Available La scelta del tempo verbale adatto a una determinata situazione dipende dal rapporto tra il momento dell’avvenimento e quello dell’enunciazione. Se coincidono abbiamo a che fare con il tempo presente (Bertinetto. È necessario, però, ricordare che il presente è in grado di riferirsi agli eventi passati come accade spesso nei testi narrativi. Per capire lo scopo di questa scelta si sono analizzati diversi tipi di scrittura comprovanti che il presente nella narrativa può servire a sottolineare la posizione temporale del narratore (Il fu Mattia Pascal; a evidenziare un momento importante dal punto di vista dello svolgimento dell’azione (Se questo è un uomo; a costruire descrizioni (Vita oppure far entrare il lettore nel vivo del racconto (Gli Italiani in Polonia nei secoli, dando l’impressione che egli sia un testimone diretto degli eventi raccontati.

Escolas de tempo integral e atividades extracurriculares: universos à espera da Psicologia brasileira

Directory of Open Access Journals (Sweden)

Neyfsom Carlos Fernandes Matias

2009-12-01

Full Text Available Observa-se que, no Brasil, diversas ações vêm sendo desenvolvidas com o intuito de se implantar uma educação em tempo integral. Sabe-se que as atividades ligadas ao esporte, às artes e culturais podem contribuir significativamente nesse sentido. Com base nisso, este artigo apresenta algumas iniciativas que visavam à execução de escolas de tempo integral e como as atividades extracurriculares podem ser úteis na efetivação de uma educação em tempo integral. O objetivo deste estudo foi o de verificar o que já se tem publicado sobre as escolas de tempo integral e atividades extracurriculares, desde uma pesquisa bibliográfica, nos periódicos “Psicologia: teoria e pesquisa”; “Psicologia: reflexão e crítica”; “Psicologia escolar e educacional”. As considerações finais apontam que o estudo sobre as atividades extracurriculares e escolas de tempo integral ainda é embrionário no Brasil e que urge a realização de pesquisas empíricas sobre atividades extracurriculares no País

Visualizing the Past: The Design of a Temporally Enabled Map for Presentation (TEMPO

Directory of Open Access Journals (Sweden)

Nathan Prestopnik

2012-01-01

Full Text Available We present a design case for a prototype visualization tool called the Temporally Enabled Map for Presentation (TEMPO. Designed for use in the lecture classroom, TEMPO is an interactive animated map that addressed a common problem in military history: the shortcomings of traditional static (non-interactive, non-animated maps. Static maps show spatial elements well, but cannot do more than approximate temporal events using multiple views, movement arrows, and the like. TEMPO provides a more complete view of past historical events by showing them from start to finish. In our design case we describe our development process, which included consultation with military history domain experts, classroom observations, application of techniques derived from visualization and Human-Computer Interaction (HCI literature and theory. Our design case shows how the design of an educational tool can motivate scholarly evaluation, and we describe how some theories were first embraced and then rejected as design circumstances required. Finally, we explore a future direction for TEMPO, tools to support creative interactions with visualizations where students or instructors can learn by visualizing historical events for themselves. A working version of the finished TEMPO artifact is included as an interactive element in this document.

The Effect of Concurrent Music Reading and Performance on the Ability to Detect Tempo Change.

Science.gov (United States)

Ellis, Mark Carlton

1989-01-01

Measures the ability of three groups of musicians to detect tempo change while reading and performing music. Compares this ability with that of the same musicians to detect tempo change while listening only. Found that for all groups the ability to detect tempo changes was inhibited by the playing task, although to different degrees for each…

TEMPO E HISTÓRIA – revisitando uma discussão conceitual

Directory of Open Access Journals (Sweden)

José D'Assunção Barros

2011-07-01

Full Text Available RESUMO:Busca-se examinar a relação entre Tempo e História, particularmente atentando para os principais conceitos referidos a esta relação: temporalidade, duração, evento, processo e outros. Em um segundo momento, desenvolve-se um contraste entre o conceito aristotélico e o conceito agostiniano de tempo, de modo a preparar as outras duas discussões do artigo: a relação entre ‘tempo da ação’ e ‘tempo da narrativa’ na construção da História, de acordo com Paul Ricoeur, e as relações entre Futuro e Passado na constituição do Presente, de acordo com as contribuições de Koselleck.PALAVRAS-CHAVE: Tempo; Narrativa; História.ABSTRACT:This article aims to examine the relation between Time and History, attempting in particular to the mainly concepts referred to this relation: Temporality, duration, event, process, and others. In a second moment, it’s developed a contrast between the Aristotelian concept and the Augustinian concept of time, in order to prepare the two other discussions of the article: the relation between ‘action time’ and ‘narrative time’ in the construction of History, according Paul Ricoeur, and the relations between Future and Past in the constitution of Present, according the contributions of Koselleck.KEYWORDS: Time, Narrative; History.Recebido: 06/02/2011         Aceito: 05/04/2011

Cochlear implant users rely on tempo rather than on pitch information during perception of musical emotion.

Science.gov (United States)

Caldwell, Meredith; Rankin, Summer K; Jiradejvong, Patpong; Carver, Courtney; Limb, Charles J

2015-09-01

The purpose of this study was to investigate the extent to which cochlear implant (CI) users rely on tempo and mode in perception of musical emotion when compared with normal hearing (NH) individuals. A test battery of novel four-bar melodies was created and adapted to four permutations with alterations of tonality (major vs. minor) and tempo (presto vs. largo), resulting in non-ambiguous (major key/fast tempo and minor key/slow tempo) and ambiguous (major key/slow tempo, and minor key/fast tempo) musical stimuli. Both CI and NH participants listened to each clip and provided emotional ratings on a Likert scale of +5 (happy) to -5 (sad). A three-way ANOVA demonstrated an overall effect for tempo in both groups, and an overall effect for mode in the NH group. The CI group rated stimuli of the same tempo similarly, regardless of changes in mode, whereas the NH group did not. A subgroup analysis indicated the same effects in both musician and non-musician CI users and NH listeners. The results suggest that the CI group relied more heavily on tempo than mode in making musical emotion decisions. The subgroup analysis further suggests that level of musical training did not significantly impact this finding. CI users weigh temporal cues more heavily than pitch cues in inferring musical emotion. These findings highlight the significant disadvantage of CI users in comparison with NH listeners for music perception, particularly during recognition of musical emotion, a critically important feature of music.

Tango or Waltz?: Putting Ballroom Dance Style into Tempo Detection

Directory of Open Access Journals (Sweden)

Gerhard Rigoll

2008-05-01

Full Text Available Rhythmic information plays an important role in Music Information Retrieval. Example applications include automatically annotating large databases by genre, meter, ballroom dance style or tempo, fully automated D.J.-ing, and audio segmentation for further retrieval tasks such as automatic chord labeling. In this article, we therefore provide an introductory overview over basic and current principles of tempo detection. Subsequently, we show how to improve on these by inclusion of ballroom dance style recognition. We introduce a feature set of 82 rhythmic features for rhythm analysis on real audio. With this set, data-driven identification of the meter and ballroom dance style, employing support vector machines, is carried out in a first step. Next, this information is used to more robustly detect tempo. We evaluate the suggested method on a large public database containing 1.8 k titles of standard and Latin ballroom dance music. Following extensive test runs, a clear boost in performance can be reported.

WACANA KEAGAMAAN SYIAH-SUNNI DALAM MAJALAH TEMPO DAN SUARA HIDAYATULLAH

Directory of Open Access Journals (Sweden)

Dadang S Anshori

2014-07-01

Full Text Available This study aims to describe the language use as representation of mass media attitudes towards Shia-Sunni conflicts. It employed the qualitative method using Fowler’s critical discourse analysis. The data source was news on Shia-Sunni conflicts in Sampang reported in Tempo and Suara Hidayatullah magazines. The findings are as follows. First, Shia-Sunni conflicts are described in news headings and points of view. Tempo describes the conflicts using the point of view of ‘devil attack’ while Suara Hidayatullah presents them as conflicts of religious understanding. Second, expressions such as ‘belief forcing’, ‘Shia cleansing’, ‘devil attack’, and ‘intolerance’ represent Tempo’s attitudes while expressions such as ‘heretical’, ‘misleading’, ‘hijacking’, ‘deifying something’, and ‘infidel’ represent Suara Hidayatullah’s attitudes. Third, based on the use of vocabulary and sentences, Tempo tends to back the Shia group while Suara Hidayatullah tends to back the Sunni group.

Nilai Eksklusivitas Dalam Karya Foto Cover Majalah Tempo Edisi 4351 Tentang Kasus Bom Sarinah 2016

Directory of Open Access Journals (Sweden)

Yohanes Christiansen Tanjung

2017-12-01

Full Text Available Visualization towards a news which is not limited on animation or photographic works in electronic media, online, and printed media has purposively been as additional information and becomes a complement of news. Particularly in spot news of the photojournalism works, every occurrence happens quite quickly. Due to photography, every moment can be recorded and well documented, as well as providing answers to what is actually happening on a rapid occurrence. One example is the use of photographs on a printed media, namely Tempo. This Research aims to observe hidden meaning in the works of photojournalism on the cover of Tempo magazine 4351 edition wether it is objective or subjective meaning that be received by the public after seeing the photo on the cover. The method used is descriptive qualitative method by conducting analysis of Peirce semiotics on the cover photo of Tempo magazine issue of 4351. Based on the research which has been done, it can be concluded that the application of visualization conducted by Tempo referred to the works of photojournalism in the cover of Tempo magazine issue of 4351 created exclusivity both in objective and subjective meaning Visualisasi pada suatu pemberitaan baik itu animasi maupun karya foto dalam media elektronik, online, dan pastinya media cetak, mempunyai tujuan sebagai informasi tambahan serta pemanis suatu berita. Khususnya pada karya foto jurnalistik spot news, setiap peristiwa yang terjadi dengan sangat cepat. Oleh karena fotografi, setiap kejadian dapat direkam dan didokumentasikan dengan baik, serta memberikan jawaban atas apa yang sebenarnya terjadi pada suatu peristiwa yang berlangsung dengan cepat. Salah satu contohnya adalah pemakaian karya foto pada sebuah cover media cetak, yaitu Tempo. Penelitian bertujuan untuk mengetahui makna yang tersembunyi dalam karya foto jurnalistik pada cover majalah Tempo edisi 4351 baik berupa makna obyektif maupun subyektif yang diterima publik setelah melihat

Estimates of the Tempo-adjusted Total Fertility Rate in Western and Eastern Germany, 1955-2008

Directory of Open Access Journals (Sweden)

Marc Luy

2011-09-01

Full Text Available In this article we present estimates of the tempo-adjusted total fertility rate in Western and Eastern Germany from 1955 to 2008. Tempo adjustment of the total fertility rate (TFR requires data on the annual number of births by parity and age of the mother. Since official statistics do not provide such data for West Germany as well as Eastern Germany from 1990 on we used alternative data sources which include these specific characteristics. The combined picture of conventional TFR and tempo-adjusted TFR* provides interesting information about the trends in period fertility in Western and Eastern Germany, above all with regard to the differences between the two regions and the enormous extent of tempo effects in Eastern Germany during the 1990s. Compared to corresponding data for populations from other countries, our estimates of the tempo-adjusted TFR* for Eastern and Western Germany show plausible trends. Nevertheless, it is important to note that the estimates of the tempo-adjusted total fertility rate presented in this paper should not be seen as being on the level of or equivalent to official statistics since they are based on different kinds of data with different degrees of quality.

Children's Preference for Sequenced Accompaniments: The Influence of Style and Perceived Tempo.

Science.gov (United States)

Brittin, Ruth V.

2000-01-01

Explores the influence of tempo on musical preference for students in grades 2-6, focusing on the effects of various styles using a MIDI keyboard. Explains that the students listened to 10 musical selections identifying their preferences and perceptions of tempo. Reveals that the preferred styles were Hip-Hop, Heavy Rock Shuffle, Samba, and Funk2.…

Importance of A Priori Vertical Ozone Profiles for TEMPO Air Quality Retrievals

Science.gov (United States)

Johnson, M. S.; Sullivan, J. T.; Liu, X.; Zoogman, P.; Newchurch, M.; Kuang, S.; McGee, T. J.; Leblanc, T.

2017-12-01

Ozone (O3) is a toxic pollutant which plays a major role in air quality. Typically, monitoring of surface air quality and O3 mixing ratios is conducted using in situ measurement networks. This is partially due to high-quality information related to air quality being limited from space-borne platforms due to coarse spatial resolution, limited temporal frequency, and minimal sensitivity to lower tropospheric and surface-level O3. The Tropospheric Emissions: Monitoring of Pollution (TEMPO) satellite is designed to address the limitations of current space-based platforms and to improve our ability to monitor North American air quality. TEMPO will provide hourly data of total column and vertical profiles of O3 with high spatial resolution to be used as a near-real-time air quality product. TEMPO O3 retrievals will apply the Smithsonian Astrophysical Observatory profile algorithm developed based on work from GOME, GOME-2, and OMI. This algorithm is suggested to use a priori O3 profile information from a climatological data-base developed from long-term ozone-sonde measurements (tropopause-based (TB-Clim) O3 climatology). This study evaluates the TB-Clim dataset and model simulated O3 profiles, which could potentially serve as a priori O3 profile information in TEMPO retrievals, from near-real-time data assimilation model products (NASA GMAO's operational GEOS-5 FP model and reanalysis data from MERRA2) and a full chemical transport model (CTM), GEOS-Chem. In this study, vertical profile products are evaluated with surface (0-2 km) and tropospheric (0-10 km) TOLNet observations and the theoretical impact of individual a priori profile sources on the accuracy of TEMPO O3 retrievals in the troposphere and at the surface are presented. Results indicate that while the TB-Clim climatological dataset can replicate seasonally-averaged tropospheric O3 profiles, model-simulated profiles from a full CTM resulted in more accurate tropospheric and surface-level O3 retrievals from

Optimal Tempo for Groove: Its Relation to Directions of Body Movement and Japanese nori

Directory of Open Access Journals (Sweden)

Takahide Etani

2018-04-01

Full Text Available The tendency for groove-based music to induce body movements has been linked to multiple acoustical factors. However, it is unclear how or whether tempo affects groove, although tempo significantly affects other aspects of music perception. To address this issue, the present study investigated effects of tempo, specific rhythmic organizations of patterns, and syncopation on groove and the induction of the sensation of wanting to move. We focused on the directions of body movement in particular by taking into account nori, which is an indigenous Japanese musical term used not only synonymously with groove, but also as a spatial metaphor indicating vertical or horizontal movement directions. Thus, the present study explored how groove was felt and defined, as well as how musical factors induced the sensation of wanting to move in cross-cultural context. A listening experiment was conducted using drum breaks as stimuli. Stimuli consisted of various rhythm patterns at six tempi from 60 to 200 BPM. The main findings are that: (1 an optimal tempo for groove existed for drum breaks at around 100–120 BPM, (2 an optimal tempo existed for the sensation of wanting to move the body in specific directions (i.e., back-and-forth and side-to-side, (3 groove and nori shared a similar concept of wanting to move but differed on several points (i.e., association with sense of pulse and fast tempo. Overall, the present study suggests that there is an optimal tempo for body movement related to groove. This finding has implications for the use of music or rhythmic stimuli to induce smooth motion in rehabilitation, therapy, or dance.

Optimal Tempo for Groove: Its Relation to Directions of Body Movement and Japanese nori.

Science.gov (United States)

Etani, Takahide; Marui, Atsushi; Kawase, Satoshi; Keller, Peter E

2018-01-01

The tendency for groove-based music to induce body movements has been linked to multiple acoustical factors. However, it is unclear how or whether tempo affects groove, although tempo significantly affects other aspects of music perception. To address this issue, the present study investigated effects of tempo, specific rhythmic organizations of patterns, and syncopation on groove and the induction of the sensation of wanting to move. We focused on the directions of body movement in particular by taking into account nori , which is an indigenous Japanese musical term used not only synonymously with groove, but also as a spatial metaphor indicating vertical or horizontal movement directions. Thus, the present study explored how groove was felt and defined, as well as how musical factors induced the sensation of wanting to move in cross-cultural context. A listening experiment was conducted using drum breaks as stimuli. Stimuli consisted of various rhythm patterns at six tempi from 60 to 200 BPM. The main findings are that: (1) an optimal tempo for groove existed for drum breaks at around 100-120 BPM, (2) an optimal tempo existed for the sensation of wanting to move the body in specific directions (i.e., back-and-forth and side-to-side), (3) groove and nori shared a similar concept of wanting to move but differed on several points (i.e., association with sense of pulse and fast tempo). Overall, the present study suggests that there is an optimal tempo for body movement related to groove. This finding has implications for the use of music or rhythmic stimuli to induce smooth motion in rehabilitation, therapy, or dance.

Thermodynamics, ecology and evolutionary biology: A bridge over troubled water or common ground?

Science.gov (United States)

Skene, Keith R.

2017-11-01

This paper addresses a key issue confronting ecological and evolutionary biology, namely the challenge of a cohesive approach to these fields given significant differences in the concepts and foundations of their study. Yet these two areas of scientific research are paramount in terms addressing the spatial and temporal dynamics and distribution of diversity, an understanding of which is needed if we are to resolve the current crisis facing the biosphere. The importance of understanding how nature responds to change is now of essential rather than of metaphysical interest as our planet struggles with increasing anthropogenic damage. Ecology and evolutionary biology can no longer remain disjointed. While some progress has been made in terms of synthetic thinking across these areas, this has often been in terms of bridge building, where thinking in one aspect is extended over to the other side. We review these bridges and the success or otherwise of such efforts. This paper then suggests that in order to move from a descriptive to a mechanistic understanding of the biosphere, we may need to re-evaluate our approach to the studies of ecology and evolutionary biology, finding a common denominator that will enable us to address the critical issues facing us, particularly in terms of understanding what drives change, what determines tempo and how communities function. Common ground, we argue, is essential if we are to comprehend how resilience operates in the natural world and how diversification can counter increasing extinction rates. This paper suggests that thermodynamics may provide a bridge between ecology and evolutionary biology, and that this will enable us to move forward with otherwise intractable problems.

Tempos históricos, tempos físicos, tempos epidemiológicos: prováveis contribuições de Fernand Braudel e Ilya Prigogine ao pensamento epidemiológico Historical times, physical times, epidemiological times: probable contributions of Fernand Braudel and Ilya Prigogine to epidemiological thinking

Directory of Open Access Journals (Sweden)

Gil Sevalho

1997-01-01

Full Text Available O texto é uma abordagem acerca do tempo enquanto categoria científica para a epidemiologia. A partir do aforismo tempo-lugar-pessoa, o tempo é apontado como elemento pouco pensado pela epidemiologia, embora esteja presente em vários dos seus conceitos. No entanto, o tema tem sido objeto de reflexão importante na movimentação recente de várias disciplinas, tais como a história, a geografia, a biologia e a física, e deve por isto representar para a epidemiologia um ponto de vista interessante, tanto no que concerne ao diálogo interdisciplinar quanto ao estabelecimento de um olhar crítico voltado para a própria disciplina. Com o objetivo de argumentar a respeito destes aspectos, apresenta-se o tempo histórico de Fernand Braudel e o tempo físico de Ilya Prigogine, construções teóricas que serão comparadas com um provável tempo epidemiológico. Ao final, usando a questão das infecções emergentes como exemplo, faz-se considerações sobre a aparente inadequação epistemológica do tempo epidemiológico para reconhecer e lidar com os aspectos sociais e históricos envolvidos na complexidade do adoecer humano coletivo.The text is an approach on time as a scientific category in epidemiology. Considering the aphorism time-place-person, time is pointed out as an element with little theoretical concern, despite its presence in main epidemiological concepts. While a topic connected to important changes in other disciplines, such as history, geography, biology and physics, time represents an interesting point of view to the interdisciplinary dialogue and its relevance for a critical knowledge in epidemiology. To argue about this idea, the historical and physical time constructions of Fernand Braudel and Ilya Prigogine are presented. These time theoretical constructions are compared with a probable epidemiological time. Finally, using the emerging infectious diseases as an example, some considerations are made about an apparent

Metal-free TEMPO-promoted C(sp³)-H amination to afford multisubstituted benzimidazoles.

Science.gov (United States)

Xue, Ding; Long, Ya-Qiu

2014-05-16

An efficient TEMPO-air/cat. TEMPO-O2 oxidative protocol was developed to synthesize multisubstituted or fused tetracyclic benzimidazoles via a metal-free oxidative C-N coupling between the sp(3) C-H and free N-H of readily available N(1)-benzyl/alkyl-1,2-phenylenediamines.

Relationship between heart rate and preference for tempo of music.

Science.gov (United States)

Iwanaga, M

1995-10-01

People prefer music with tempi ranging from 70 to 100 cycles per minute similar to that of adults' heart rate within normal daily situations. Previous studies of the relation between preferred tempi and heart rates using a pure tone also have indicated that subjects tended to prefer tempi similar to their heart rates. The present study examined this relationship using a musical piece (the theme of "It's a small world") as a stimulus. 14 undergraduate women were subjects who searched for their favorite tempi by controlling the musical tempo by themselves. The most preferred tempo was close to their cycle of heart beats, however, tempi that were one and a half and twice as fast as the heart rate were less preferred in the present study than in a previous study using a tone. Subjects preferred faster tempi in the descending series of stimuli than in the ascending one, and hence were influenced by the initial value of the tempo in the trial sequence. The effects due to the differences of the meaning of the stimuli are considered.

Oltre lo spazio e il tempo la nuova fisica

CERN Document Server

Lachièze-Rey, Marc

2004-01-01

Oggi la fisica si fonda, allo stesso tempo, sulla meccanica quantistica e sulla relatività generale. Ma, in quanto veri e propri sistemi di pensiero, queste due teorie suggeriscono due distinte visioni del mondo, non conciliabili nel quadro di una descrizione unificata. Se dunque la fisica attuale si rivela inadeguata, occorre costruirne una nuova, percorrendo fino in fondo la via geometrica. Supersimmetria, stringhe e superstringhe, gravità e cosmologia quantistiche, geometria non commutativa: nuove audaci ipotesi al servizio di nuove teorie che rinnovano la nostra concezione dello spazio, del tempo, della materia e dell'Universo, e che trovano nel volume una presentazione chiara e accessibile anche a un pubblico di non specialisti.

Evaluating A Priori Ozone Profile Information Used in TEMPO Tropospheric Ozone Retrievals

Science.gov (United States)

Johnson, Matthew S.; Sullivan, John T.; Liu, Xiong; Newchurch, Mike; Kuang, Shi; McGee, Thomas J.; Langford, Andrew O'Neil; Senff, Christoph J.; Leblanc, Thierry; Berkoff, Timothy;

Evaluating A Priori Ozone Profile Information Used in TEMPO Tropospheric Ozone Retrievals

Science.gov (United States)

Johnson, M. S.; Sullivan, J. T.; Liu, X.; Newchurch, M.; Kuang, S.; McGee, T. J.; Langford, A. O.; Senff, C. J.; Leblanc, T.; Berkoff, T.; Gronoff, G.; Chen, G.; Strawbridge, K. B.

2016-12-01

Ozone (O3) is a greenhouse gas and toxic pollutant which plays a major role in air quality. Typically, monitoring of surface air quality and O3 mixing ratios is primarily conducted using in situ measurement networks. This is partially due to high-quality information related to air quality being limited from space-borne platforms due to coarse spatial resolution, limited temporal frequency, and minimal sensitivity to lower tropospheric and surface-level O3. The Tropospheric Emissions: Monitoring of Pollution (TEMPO) satellite is designed to address these limitations of current space-based platforms and to improve our ability to monitor North American air quality. TEMPO will provide hourly data of total column and vertical profiles of O3 with high spatial resolution to be used as a near-real-time air quality product. TEMPO O3 retrievals will apply the Smithsonian Astrophysical Observatory profile algorithm developed based on work from GOME, GOME-2, and OMI. This algorithm uses a priori O3 profile information from a climatological data-base developed from long-term ozone-sonde measurements (tropopause-based (TB) O3 climatology). It has been shown that satellite O3 retrievals are sensitive to a priori O3 profiles and covariance matrices. During this work we investigate the climatological data to be used in TEMPO algorithms (TB O3) and simulated data from the NASA GMAO Goddard Earth Observing System (GEOS-5) Forward Processing (FP) near-real-time (NRT) model products. These two data products will be evaluated with ground-based lidar data from the Tropospheric Ozone Lidar Network (TOLNet) at various locations of the US. This study evaluates the TB climatology, GEOS-5 climatology, and 3-hourly GEOS-5 data compared to lower tropospheric observations to demonstrate the accuracy of a priori information to potentially be used in TEMPO O3 algorithms. Here we present our initial analysis and the theoretical impact on TEMPO retrievals in the lower troposphere.

Manipulating Greek musical modes and tempo affects perceived musical emotion in musicians and nonmusicians.

Science.gov (United States)

Ramos, D; Bueno, J L O; Bigand, E

2011-02-01

The combined influence of tempo and mode on emotional responses to music was studied by crossing 7 changes in mode with 3 changes in tempo. Twenty-four musicians aged 19 to 25 years (12 males and 12 females) and 24 nonmusicians aged 17 to 25 years (12 males and 12 females) were required to perform two tasks: 1) listening to different musical excerpts, and 2) associating an emotion to them such as happiness, serenity, fear, anger, or sadness. ANOVA showed that increasing the tempo strongly affected the arousal (F(2,116) = 268.62, mean square error (MSE) = 0.6676, P effects were found between tempo and mode (F (1,58) = 115.6, MSE = 0.6428, P effects. This finding demonstrates that small changes in the pitch structures of modes modulate the emotions associated with the pieces, confirming the cognitive foundation of emotional responses to music.

A developmental study of the affective value of tempo and mode in music.

Science.gov (United States)

Dalla Bella, S; Peretz, I; Rousseau, L; Gosselin, N

2001-07-01

Do children use the same properties as adults in determining whether music sounds happy or sad? We addressed this question with a set of 32 excerpts (16 happy and 16 sad) taken from pre-existing music. The tempo (i.e. the number of beats per minute) and the mode (i.e. the specific subset of pitches used to write a given musical excerpt) of these excerpts were modified independently and jointly in order to measure their effects on happy-sad judgments. Adults and children from 3 to 8 years old were required to judge whether the excerpts were happy or sad. The results show that as adults, 6--8-year-old children are affected by mode and tempo manipulations. In contrast, 5-year-olds' responses are only affected by a change of tempo. The youngest children (3--4-year-olds) failed to distinguish the happy from the sad tone of the music above chance. The results indicate that tempo is mastered earlier than mode to infer the emotional tone conveyed by music.

Effect of TEMPO-oxidization and rapid cooling on thermo-structural properties of nanocellulose.

Science.gov (United States)

Mhd Haniffa, Mhd Abd Cader; Ching, Yern Chee; Chuah, Cheng Hock; Yong Ching, Kuan; Nazri, Nik; Abdullah, Luqman Chuah; Nai-Shang, Liou

2017-10-01

Recently, surface functionality and thermal property of the green nanomaterials have received wide attention in numerous applications. In this study, microcrystalline cellulose (MCC) was used to prepare the nanocrystalline celluloses (NCCs) using acid hydrolysis method. The NCCs was treated with TEMPO [(2,2,6,6-tetramethylpiperidin-1-yl)oxy radical]-oxidation to prepare TEMPO-oxidized NCCs. Cellulose nanofibrils (CNFs) also prepared from MCC using TEMPO-oxidation. The effects of rapid cooling and chemical treatments on the thermo-structural property studies of the prepared nanocelluloses were investigated through FTIR, thermogravimetric analysis-derivative thermogravimetric (TGA-DTG), and XRD. A posteriori knowledge of the FTIR and TGA-DTG analysis revealed that the rapid cooling treatment enhanced the hydrogen bond energy and thermal stability of the TEMPO-oxidized NCC compared to other nanocelluloses. XRD analysis exhibits the effect of rapid cooling on pseudo 2 I helical conformation. This was the first investigation performed on the effect of rapid cooling on structural properties of the nanocellulose. Copyright © 2017 Elsevier Ltd. All rights reserved.

Tempo e Trânsito na Experiência Subjetiva de Motoristas

OpenAIRE

Ana Inez Oka Elvas de Lima; Sylvia Cavalcante

2015-01-01

Esta pesquisa investiga como são percebidos e vivenciados o tempo e a pressa no trânsito por motoristas de Fortaleza, identificando e analisando seus estados subjetivos e comportamentos associados a essa experiência. Para a coleta de dados, organizaram-se quatro grupos focais, a partir dos quais emergiram diversos elementos relacionados ao tempo e à pressa e à incidência de comportamentos inadequados no trânsito, segundo o sexo e a idade dos participantes. Para analisar os dados obtidos nas d...

Ultra-low fertility in South Korea: The role of the tempo effect

Directory of Open Access Journals (Sweden)

Sam Hyun Yoo

2018-02-01

Full Text Available Background: The total fertility rate (TFR in South Korea has fallen below 1.3 since 2001. The role of the rapid shift toward a late-childbearing pattern in driving Korean fertility decline to this ultra-low level has been little explored until now. Objective: We provide an in-depth analysis of period fertility trends by birth order in South Korea from 1981 to 2015, when the period TFR fell from 2.57 to extremely low levels. Methods: We combine census and birth registration data to estimate period and cohort fertility indicators by birth order. We compare changes in conventional TFR with tempo- and parity-adjusted total fertility rate (TFRp* and their birth-order-specific components. Results: The tempo effect linked to the shift toward delayed childbearing has had a strong and persistent negative influence on period TFRs in South Korea since the early 1980s. Without the shift to later childbearing, period fertility rates in South Korea would consistently stay higher and decline more gradually, reaching a threshold of very low fertility, 1.5, only in 2014. The postponement of childbearing and the resulting tempo effect were strongest in the early 2000s, when Korean TFR reached the lowest levels. More recently, Korean fertility has been characterized by a diminishing tempo effect and falling first and second birth rates. This trend marks a break with the previous pattern of almost universal fertility and a strong two-child family model. Contribution: Our study demonstrates the importance of the tempo effect in explaining the shift to ultra-low fertility in South Korea and in East Asia

A TEMPO-free copper-catalyzed aerobic oxidation of alcohols.

Science.gov (United States)

Xu, Boran; Lumb, Jean-Philip; Arndtsen, Bruce A

2015-03-27

The copper-catalyzed aerobic oxidation of primary and secondary alcohols without an external N-oxide co-oxidant is described. The catalyst system is composed of a Cu/diamine complex inspired by the enzyme tyrosinase, along with dimethylaminopyridine (DMAP) or N-methylimidazole (NMI). The Cu catalyst system works without 2,2,6,6-tetramethyl-l-piperidinoxyl (TEMPO) at ambient pressure and temperature, and displays activity for un-activated secondary alcohols, which remain a challenging substrate for catalytic aerobic systems. Our work underscores the importance of finding alternative mechanistic pathways for alcohol oxidation, which complement Cu/TEMPO systems, and demonstrate, in this case, a preference for the oxidation of activated secondary over primary alcohols. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Structural, thermal and photo-physical data of azo-aromatic TEMPO derivatives before and after their grafting to polyolefins

Directory of Open Access Journals (Sweden)

Francesca Cicogna

2016-03-01

Full Text Available The data reported in this paper are complementary to the characterization of 4-(phenylazo-benzoyl-2,2,6,6-tetramethylpiperidine-1-oxyl radical (AzO-TEMPO and of the 4-(2-thienylazo-benzoyl-2,2,6,6-tetramethylpiperidine-1-oxyl radical (ThiO-TEMPO before and after their grafting to two polyethylene matrices (a copolymer ethylene/α-olefin (co-EO and a high density polyethylene (HDPE. Particularly the data reported in this paper confirm the structure (FT-IR analysis, the thermal (TGA and EPR and the photo-physical (UV–vis properties of the RO-TEMPO derivatives before and after their grafting. Herein, the FT-IR spectrum and TGA thermogram of ThiO-TEMPO were compared with those of AzO-TEMPO. Moreover, the superimposition of UV–vis spectra collected during the irradiation under 366 or 254 nm emitting lamp of AzO-TEMPO and ThiO-TEMPO in acetonitrile solution are reported. Finally, a complete DSC characterization of the functionalized POs is shown.DOI of original article: 〈http://dx.doi.org/10.1016/j.polymer.2015.11.018〉 [1

Tempos de infância, tempos de escola: a ordenação do tempo escolar no ensino público paulista (1892-1933 Childhood times, school times: the ordering of school time in the São Paulo State School System (1892-1933

Directory of Open Access Journals (Sweden)

Rosa Fátima de Souza

1999-07-01

Full Text Available O texto analisa a ordenação do tempo nas escolas primárias paulistas no final do século XIX e início do século XX, período em que se institui e se consolida a arquitetura temporal escolar. Compreende, pois, as primeiras prescrições detalhadas sobre o tempo constantes na reforma republicana da instrução pública de 1892, as regulamentações instituídas no decorrer da Primeira República, até o momento de criação do Código de Educação de São Paulo em 1933, quando se inaugura uma nova fase da instrução pública no estado. O texto busca mostrar como o tempo constitui uma ordem que se experimenta e se aprende na escola. Para a realização deste estudo foram utilizadas fontes documentais, especialmente a legislação e textos oficiais da administração do ensino. As análises incidem sobre dois aspectos: a formulação política do tempo escolar e a organização pedagógica e disciplinar do tempo na escola. Em relação ao primeiro aspecto, mostra como a ordenação do tempo pautou-se pela aspiração de uniformização e controle. Nesse sentido, as autoridades do ensino público procuraram regulamentar a obrigatoriedade do ensino, a freqüência, a duração do curso primário e a jornada escolar. Em relação à organização pedagógica e disciplinar do tempo, põe em destaque a ordenação minuciosa do emprego do tempo compreendendo a racionalização curricular - a seleção e distribuição do conhecimento por séries, aulas, lições, e a definição dos horários.This text analyzes the ordering of time in primary state schools of the State of São Paulo at the end of the 19th century and beginning of the 20th century, a period in which the school time architecture is instated and consolidated. The paper thus starts with the first detailed instructions related to time at schools, which are part of the Republican Reform of Public Schooling of 1892. It continues with the regulations elaborated during the First Republic

Effect of Melodic Rhythm on Elementary Students' and College Undergraduates' Perceptions of Relative Tempo.

Science.gov (United States)

Duke, Robert A.

1989-01-01

Uses extant musical examples as stimuli in order to assess the effect of melodic rhythm as a determinant of relative tempo as perceived by college undergraduates and elementary students. Results indicate that subjects responded to the melodic rhythm as well as the beat when making tempo judgments. (LS)

Determinação da Distribuição de Tempos de Residência em Tempo Real no Processamento Reativo de Blendas Poliméricas

Directory of Open Access Journals (Sweden)

Mélo Tomás J. A. de

2002-01-01

Full Text Available Determinou-se por transmissão de luz a distribuição de tempos de residência (DTR em tempo real em uma extrusora com rosca dupla co-rotativa e autolimpante onde o sinal do detetor é sensível à presença da segunda fase dispersa, usada como traçador. Vários traçadores foram utilizados em diferentes concentrações: dois pigmentos (TiO2 e ftalocianina e dois polímeros (poliestireno PS e poliamida-6 PA6 sendo adicionados na forma de um pulso em um fluxo de polipropileno (PP. Os parâmetros temporais (tempos de residência inicial, t i e médio t n e a variância normalizada s q² medidos nas mesmas condições de processamento são muito próximos, dentro do erro experimental, indicando que a dispersão axial neste tipo de extrusora é independente do traçador. Por outro lado curvas de DTR medidas usando-se um polímero traçador (PS disperso em um polímero de fluxo (PP ficam deslocadas no tempo quando a situação é invertida, ou seja, usando-se PP como traçador em um fluxo de PS. Os parâmetros temporais são dependentes das características reológicas do polímero de fluxo, assim diferentes tipos de um mesmo polímero apresentam DTR com formas diferentes e deslocadas no tempo. A intensidade do sinal produzido pelo detetor é dependente não só da concentração mas também das características ópticas do par polímero/traçador, ou polímero/fase dispersa. Misturas poliméricas reativas (PP/PA6/PP-g-AA e não reativas (PP/PA6 apresentaram diferenças na intensidade do sinal da DTR, devido à ocorrência da reação de graftização com conseqüente mudança na morfologia e no comportamento reológico. Estes resultados foram corroborados com medidas "off-line" por espectroscopia no infravermelho.

Relational invariance of expressive microstructure across global tempo changes in music performance: an exploratory study.

Science.gov (United States)

Repp, B H

1994-01-01

This study addressed the question of whether the expressive microstructure of a music performance remains relationally invariant across moderate (musically acceptable) changes in tempo. Two pianists played Schumann's "Träumerei" three times at each of three tempi on a digital piano, and the performance data were recorded in MIDI format. In a perceptual test, musically trained listeners attempted to distinguish the original performances from performances that had been artificially speeded up or slowed down to the same overall duration. Accuracy in this task was barely above chance, suggesting that relational invariance was largely preserved. Subsequent analysis of the MIDI data confirmed that each pianist's characteristic timing patterns were highly similar across the three tempi, although there were statistically significant deviations from perfect relational invariance. The timing of (relatively slow) grace notes seemed relationally invariant, but selective examination of other detailed temporal features (chord asynchrony, tone overlap, pedal timing) revealed no systematic scaling with tempo. Finally, although the intensity profile seemed unaffected by tempo, a slight overall increase in intensity with tempo was observed. Effects of musical structure on expressive microstructure were large and pervasive at all levels, as were individual differences between the two pianists. For the specific composition and range of tempi considered here, these results suggest that major (cognitively controlled) temporal and dynamic features of a performance change roughly in proportion with tempo, whereas minor features tend to be governed by tempo-independent motoric constraints.

Evolution in health and medicine Sackler colloquium: Making evolutionary biology a basic science for medicine.

Science.gov (United States)

Nesse, Randolph M; Bergstrom, Carl T; Ellison, Peter T; Flier, Jeffrey S; Gluckman, Peter; Govindaraju, Diddahally R; Niethammer, Dietrich; Omenn, Gilbert S; Perlman, Robert L; Schwartz, Mark D; Thomas, Mark G; Stearns, Stephen C; Valle, David

2010-01-26

New applications of evolutionary biology in medicine are being discovered at an accelerating rate, but few physicians have sufficient educational background to use them fully. This article summarizes suggestions from several groups that have considered how evolutionary biology can be useful in medicine, what physicians should learn about it, and when and how they should learn it. Our general conclusion is that evolutionary biology is a crucial basic science for medicine. In addition to looking at established evolutionary methods and topics, such as population genetics and pathogen evolution, we highlight questions about why natural selection leaves bodies vulnerable to disease. Knowledge about evolution provides physicians with an integrative framework that links otherwise disparate bits of knowledge. It replaces the prevalent view of bodies as machines with a biological view of bodies shaped by evolutionary processes. Like other basic sciences, evolutionary biology needs to be taught both before and during medical school. Most introductory biology courses are insufficient to establish competency in evolutionary biology. Premedical students need evolution courses, possibly ones that emphasize medically relevant aspects. In medical school, evolutionary biology should be taught as one of the basic medical sciences. This will require a course that reviews basic principles and specific medical applications, followed by an integrated presentation of evolutionary aspects that apply to each disease and organ system. Evolutionary biology is not just another topic vying for inclusion in the curriculum; it is an essential foundation for a biological understanding of health and disease.

TEMPO addition into pre-irradiated fluoropolymers and living-radical graft polymerization of styrene for preparation of polymer electrolyte membranes

Energy Technology Data Exchange (ETDEWEB)

Sawada, Shin-ichi, E-mail: sawada.shinnichi@jaea.go.j [Conducting Polymer Materials Research Group, Quantum Beam Science Directorate, Japan Atomic Energy Agency (JAEA), 1233 Watanuki, Takasaki, Gunma 370-1292 (Japan); Department of Nuclear Engineering and Management, Graduate School of Engineering, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan); Suzuki, Akihiro; Terai, Takayuki [Department of Nuclear Engineering and Management, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan); Maekawa, Yasunari, E-mail: maekawa.yasunari@jaea.go.j [Conducting Polymer Materials Research Group, Quantum Beam Science Directorate, Japan Atomic Energy Agency (JAEA), 1233 Watanuki, Takasaki, Gunma 370-1292 (Japan)

2010-04-15

We prepared proton exchange membranes (PEMs) by 2,2,6,6-tetramethylpiperidinyl-1-oxy (TEMPO)-mediated living-radical graft polymerization (LRGP) of styrene into fluoropolymer films and subsequent sulfonation. Poly(vinylidene fluoride) (PVDF) and poly(ethylene-co-tetrafluoroethylene) (ETFE) films were first irradiated and then treated with TEMPO solutions in various solvents. TEMPO addition was confirmed by the test of styrene grafting into TEMPO-treated films at 60 deg. C, at which the LRGP never proceeds. This test enabled us to differentiate the LRGP from the conventional graft polymerization. In order to gain a deep insight about TEMPO-addition reaction, the TEMPO-penetration behavior into the base polymer films was examined by a permeation experiment and computer simulation. Xylene and dioxane were appropriate solvents for the complete introduction of TEMPO into PVDF and ETFE films, respectively. Then, the LRGP of styrene was performed based on the fully TEMPO-capped films at 125 deg. C with various solvents. By using an alcoholic solvent, the degree of grafting was enhanced and it reached a maximum of 38%. This grafted film was sulfonated to prepare a PEM showing an ion exchange capacity of 2.2 meq/g and proton conductivity of 1.6x10{sup -1} S/cm.

Lokasi Dan Kelompok Teater Indonesia 2001-2005 (Analisis Rubrik Teater Majalah Tempo

Directory of Open Access Journals (Sweden)

Nurhadi Nurhadi

2010-06-01

Full Text Available Artikel ini bertujuan mendeskripsikan kelompok-kelompok teater yang berkecimpung dalam pementasan teater di Indonesia dan peta lokasi pementasan sebagaimana diulas dalam majalah Tempo tahun 2001-2005. Hasil penelitian ini menunjukan kelompok teater yang paling konsisten dalam mementaskan suatu naskah setiap tahunnya adalah Teater Koma. Kelompok teater berikutnya yang relatif banyak berkiprah dari tahun 2001-2005 berdasarkan artikel rubrik teater Tempo yaitu Teater Mandiri, Teater Garasi, dan Actors Unlimited Bandung. Kelompok teater pada jajaran berikutnya yang mementaskan lebih dari satu kali pada periode 2001-2005, yaitu Teater Gandrik, Bengkel Teater, dan Mainteater Jakarta. Lokasi pementasan teater selama 2001-2005 berdasarkan rubrik teater majalah Tempo sebagian besar berlangsung di berbagai gedung teater di Jakarta. Perbandingan jumlah lokasi pertunjukannya adalah sebagai berikut: Jakarta (50 pementasan, Yogyakarta (6 pementasan, Surakarta (2 pementasan dan Bandung (1 pementasan. Abstract: This article aims to describe the theater groups being active in theater performances in Indonesia and the performance location map as reviewed in Tempo magazine in 2001-2005. The research result has shown that the most consistent theater group in performing a script each year is Teater Koma. The next group which have relatively many performances in 2001-2005 according to Tempo’s articles are Teater Mandiri, Teater Garasi, and Actors Unlimited Bandung. The next level groups which have more than one performance in 2001-2005 are Teater Gandrik, Bengkel Teater, and Mainteater Jakarta. The theater performance locations in 2001-2005, according to Tempo’s articles, mostly took place in Jakarta’s theater houses. The ratio of performance locations amount is as follows: Jakarta (50 performances, Yogyakarta (6 performances, Surakarta (2 performances, and Bandung (1 performance. Key Words: theater performance location, theater group, Tempo magazine

Pentacene appended to a TEMPO stable free radical: the effect of magnetic exchange coupling on photoexcited pentacene.

Science.gov (United States)

Chernick, Erin T; Casillas, Rubén; Zirzlmeier, Johannes; Gardner, Daniel M; Gruber, Marco; Kropp, Henning; Meyer, Karsten; Wasielewski, Michael R; Guldi, Dirk M; Tykwinski, Rik R

2015-01-21

Understanding the fundamental spin dynamics of photoexcited pentacene derivatives is important in order to maximize their potential for optoelectronic applications. Herein, we report on the synthesis of two pentacene derivatives that are functionalized with the [(2,2,6,6-tetramethylpiperidin-1-yl)oxy] (TEMPO) stable free radical. The presence of TEMPO does not quench the pentacene singlet excited state, but does quench the photoexcited triplet excited state as a function of TEMPO-to-pentacene distance. Time-resolved electron paramagnetic resonance experiments confirm that triplet quenching is accompanied by electron spin polarization transfer from the pentacene excited state to the TEMPO doublet state in the weak coupling regime.

Representasi Pemberitaan Wanita Pelaku Kejahatan di Media Massa (Analisis Karikatur dan Konten Berita Malinda Dee di Majalah TEMPO)

OpenAIRE

Lubis, Ghassani S.

2015-01-01

This research titled “Representation of Women Offenders Reporting in Mass Media”. A Study of semiotics analysis of TEMPO magazine‟s front covers and news content on editions in April 4th and 11th 2011. Caricature cover and news content of TEMPO has been analyzed to discover the meaning and myths and representation of Malinda Dee in TEMPO magazine. Malinda cover design TEMPO edition number 05/40 (4th April 2011) and 06/40 (11th April 2011), depicting two historical females in the world that is...

Tempo e Trânsito na Experiência Subjetiva de Motoristas

Directory of Open Access Journals (Sweden)

Ana Inez Oka Elvas de Lima

2015-03-01

Full Text Available Esta pesquisa investiga como são percebidos e vivenciados o tempo e a pressa no trânsito por motoristas de Fortaleza, identificando e analisando seus estados subjetivos e comportamentos associados a essa experiência. Para a coleta de dados, organizaram-se quatro grupos focais, a partir dos quais emergiram diversos elementos relacionados ao tempo e à pressa e à incidência de comportamentos inadequados no trânsito, segundo o sexo e a idade dos participantes. Para analisar os dados obtidos nas discussões grupais utilizaram-se os critérios da Análise Clássica de Conteúdo. Os resultados levaram à conclusão de que a questão do tempo e da pressa constitui um potencial gerador de erros e violações na condução de veículos, pois exerce influência decisiva sobre os comportamentos dos motoristas e configura uma realidade importante para se compreender os fatores humanos envolvidos na dinâmica do trânsito e do ambiente urbano como um todo.

Directed Motor-Auditory EEG Connectivity Is Modulated by Music Tempo.

Science.gov (United States)

Nicolaou, Nicoletta; Malik, Asad; Daly, Ian; Weaver, James; Hwang, Faustina; Kirke, Alexis; Roesch, Etienne B; Williams, Duncan; Miranda, Eduardo R; Nasuto, Slawomir J

2017-01-01

Beat perception is fundamental to how we experience music, and yet the mechanism behind this spontaneous building of the internal beat representation is largely unknown. Existing findings support links between the tempo (speed) of the beat and enhancement of electroencephalogram (EEG) activity at tempo-related frequencies, but there are no studies looking at how tempo may affect the underlying long-range interactions between EEG activity at different electrodes. The present study investigates these long-range interactions using EEG activity recorded from 21 volunteers listening to music stimuli played at 4 different tempi (50, 100, 150 and 200 beats per minute). The music stimuli consisted of piano excerpts designed to convey the emotion of "peacefulness". Noise stimuli with an identical acoustic content to the music excerpts were also presented for comparison purposes. The brain activity interactions were characterized with the imaginary part of coherence (iCOH) in the frequency range 1.5-18 Hz (δ, θ, α and lower β) between all pairs of EEG electrodes for the four tempi and the music/noise conditions, as well as a baseline resting state (RS) condition obtained at the start of the experimental task. Our findings can be summarized as follows: (a) there was an ongoing long-range interaction in the RS engaging fronto-posterior areas; (b) this interaction was maintained in both music and noise, but its strength and directionality were modulated as a result of acoustic stimulation; (c) the topological patterns of iCOH were similar for music, noise and RS, however statistically significant differences in strength and direction of iCOH were identified; and (d) tempo had an effect on the direction and strength of motor-auditory interactions. Our findings are in line with existing literature and illustrate a part of the mechanism by which musical stimuli with different tempi can entrain changes in cortical activity.

Directed Motor-Auditory EEG Connectivity Is Modulated by Music Tempo

Directory of Open Access Journals (Sweden)

Nicoletta Nicolaou

2017-10-01

Full Text Available Beat perception is fundamental to how we experience music, and yet the mechanism behind this spontaneous building of the internal beat representation is largely unknown. Existing findings support links between the tempo (speed of the beat and enhancement of electroencephalogram (EEG activity at tempo-related frequencies, but there are no studies looking at how tempo may affect the underlying long-range interactions between EEG activity at different electrodes. The present study investigates these long-range interactions using EEG activity recorded from 21 volunteers listening to music stimuli played at 4 different tempi (50, 100, 150 and 200 beats per minute. The music stimuli consisted of piano excerpts designed to convey the emotion of “peacefulness”. Noise stimuli with an identical acoustic content to the music excerpts were also presented for comparison purposes. The brain activity interactions were characterized with the imaginary part of coherence (iCOH in the frequency range 1.5–18 Hz (δ, θ, α and lower β between all pairs of EEG electrodes for the four tempi and the music/noise conditions, as well as a baseline resting state (RS condition obtained at the start of the experimental task. Our findings can be summarized as follows: (a there was an ongoing long-range interaction in the RS engaging fronto-posterior areas; (b this interaction was maintained in both music and noise, but its strength and directionality were modulated as a result of acoustic stimulation; (c the topological patterns of iCOH were similar for music, noise and RS, however statistically significant differences in strength and direction of iCOH were identified; and (d tempo had an effect on the direction and strength of motor-auditory interactions. Our findings are in line with existing literature and illustrate a part of the mechanism by which musical stimuli with different tempi can entrain changes in cortical activity.

Directed Motor-Auditory EEG Connectivity Is Modulated by Music Tempo

Science.gov (United States)

Nicolaou, Nicoletta; Malik, Asad; Daly, Ian; Weaver, James; Hwang, Faustina; Kirke, Alexis; Roesch, Etienne B.; Williams, Duncan; Miranda, Eduardo R.; Nasuto, Slawomir J.

2017-01-01

Beat perception is fundamental to how we experience music, and yet the mechanism behind this spontaneous building of the internal beat representation is largely unknown. Existing findings support links between the tempo (speed) of the beat and enhancement of electroencephalogram (EEG) activity at tempo-related frequencies, but there are no studies looking at how tempo may affect the underlying long-range interactions between EEG activity at different electrodes. The present study investigates these long-range interactions using EEG activity recorded from 21 volunteers listening to music stimuli played at 4 different tempi (50, 100, 150 and 200 beats per minute). The music stimuli consisted of piano excerpts designed to convey the emotion of “peacefulness”. Noise stimuli with an identical acoustic content to the music excerpts were also presented for comparison purposes. The brain activity interactions were characterized with the imaginary part of coherence (iCOH) in the frequency range 1.5–18 Hz (δ, θ, α and lower β) between all pairs of EEG electrodes for the four tempi and the music/noise conditions, as well as a baseline resting state (RS) condition obtained at the start of the experimental task. Our findings can be summarized as follows: (a) there was an ongoing long-range interaction in the RS engaging fronto-posterior areas; (b) this interaction was maintained in both music and noise, but its strength and directionality were modulated as a result of acoustic stimulation; (c) the topological patterns of iCOH were similar for music, noise and RS, however statistically significant differences in strength and direction of iCOH were identified; and (d) tempo had an effect on the direction and strength of motor-auditory interactions. Our findings are in line with existing literature and illustrate a part of the mechanism by which musical stimuli with different tempi can entrain changes in cortical activity. PMID:29093672

What's in a Name: Is “Evolutionary Psychology” Eclipsing “Sociobiology” in the Scientific Literature?

Directory of Open Access Journals (Sweden)

Gregory D. Webster

2007-10-01

Full Text Available Is the term “evolutionary psychology” supplanting “sociobiology” in the scientific literature? How influential was E. O. Wilson's (1975 book, Sociobiology, in establishing the discipline of the same name? Similarly, how influential were the two Tooby-Cosmides chapters appearing in The Adapted Mind (Cosmides and Tooby, 1992; Tooby and Cosmides, 1992 in establishing evolutionary psychology as a viable outgrowth of sociobiology? The purpose of the present research was to answer these questions using quantitative analyses of publication trends. The Internet search engine Google Scholar was used to count the number of hits (i.e., the number of scholarly works, citations, etc. for “sociobiology” and “evolutionary psychology” separately per year from 1960 to 2003. Interrupted time-series analyses revealed significant increases (intercept shifts for sociobiology hits between 1974 and 1975, and for evolutionary psychology hits between 1991 and 1992. Evolutionary psychology hits also experienced a significant increase in change-over-time (a slope shift between 1991 and 1992. Growth curve analyses revealed that the rate of growth for evolutionary psychology, which was accelerating over time, was significantly greater than that for sociobiology, which was decelerating. The implications of these findings for understanding the histories of sociobiology and evolutionary psychology are discussed.

Evolutionary Nephrology.

Science.gov (United States)

Chevalier, Robert L

2017-05-01

Progressive kidney disease follows nephron loss, hyperfiltration, and incomplete repair, a process described as "maladaptive." In the past 20 years, a new discipline has emerged that expands research horizons: evolutionary medicine. In contrast to physiologic (homeostatic) adaptation, evolutionary adaptation is the result of reproductive success that reflects natural selection. Evolutionary explanations for physiologically maladaptive responses can emerge from mismatch of the phenotype with environment or evolutionary tradeoffs. Evolutionary adaptation to a terrestrial environment resulted in a vulnerable energy-consuming renal tubule and a hypoxic, hyperosmolar microenvironment. Natural selection favors successful energy investment strategy: energy is allocated to maintenance of nephron integrity through reproductive years, but this declines with increasing senescence after ~40 years of age. Risk factors for chronic kidney disease include restricted fetal growth or preterm birth (life history tradeoff resulting in fewer nephrons), evolutionary selection for APOL1 mutations (that provide resistance to trypanosome infection, a tradeoff), and modern life experience (Western diet mismatch leading to diabetes and hypertension). Current advances in genomics, epigenetics, and developmental biology have revealed proximate causes of kidney disease, but attempts to slow kidney disease remain elusive. Evolutionary medicine provides a complementary approach by addressing ultimate causes of kidney disease. Marked variation in nephron number at birth, nephron heterogeneity, and changing susceptibility to kidney injury throughout life history are the result of evolutionary processes. Combined application of molecular genetics, evolutionary developmental biology (evo-devo), developmental programming and life history theory may yield new strategies for prevention and treatment of chronic kidney disease.

Evolutionary Nephrology

Directory of Open Access Journals (Sweden)

Robert L. Chevalier

2017-05-01

Full Text Available Progressive kidney disease follows nephron loss, hyperfiltration, and incomplete repair, a process described as “maladaptive.” In the past 20 years, a new discipline has emerged that expands research horizons: evolutionary medicine. In contrast to physiologic (homeostatic adaptation, evolutionary adaptation is the result of reproductive success that reflects natural selection. Evolutionary explanations for physiologically maladaptive responses can emerge from mismatch of the phenotype with environment or from evolutionary tradeoffs. Evolutionary adaptation to a terrestrial environment resulted in a vulnerable energy-consuming renal tubule and a hypoxic, hyperosmolar microenvironment. Natural selection favors successful energy investment strategy: energy is allocated to maintenance of nephron integrity through reproductive years, but this declines with increasing senescence after ∼40 years of age. Risk factors for chronic kidney disease include restricted fetal growth or preterm birth (life history tradeoff resulting in fewer nephrons, evolutionary selection for APOL1 mutations (which provide resistance to trypanosome infection, a tradeoff, and modern life experience (Western diet mismatch leading to diabetes and hypertension. Current advances in genomics, epigenetics, and developmental biology have revealed proximate causes of kidney disease, but attempts to slow kidney disease remain elusive. Evolutionary medicine provides a complementary approach by addressing ultimate causes of kidney disease. Marked variation in nephron number at birth, nephron heterogeneity, and changing susceptibility to kidney injury throughout the life history are the result of evolutionary processes. Combined application of molecular genetics, evolutionary developmental biology (evo-devo, developmental programming, and life history theory may yield new strategies for prevention and treatment of chronic kidney disease.

The Genealogical Population Dynamics of HIV-1 in a Large Transmission Chain: Bridging within and among Host Evolutionary Rates

Science.gov (United States)

Vrancken, Bram; Rambaut, Andrew; Suchard, Marc A.; Drummond, Alexei; Baele, Guy; Derdelinckx, Inge; Van Wijngaerden, Eric; Vandamme, Anne-Mieke; Van Laethem, Kristel; Lemey, Philippe

2014-01-01

Transmission lies at the interface of human immunodeficiency virus type 1 (HIV-1) evolution within and among hosts and separates distinct selective pressures that impose differences in both the mode of diversification and the tempo of evolution. In the absence of comprehensive direct comparative analyses of the evolutionary processes at different biological scales, our understanding of how fast within-host HIV-1 evolutionary rates translate to lower rates at the between host level remains incomplete. Here, we address this by analyzing pol and env data from a large HIV-1 subtype C transmission chain for which both the timing and the direction is known for most transmission events. To this purpose, we develop a new transmission model in a Bayesian genealogical inference framework and demonstrate how to constrain the viral evolutionary history to be compatible with the transmission history while simultaneously inferring the within-host evolutionary and population dynamics. We show that accommodating a transmission bottleneck affords the best fit our data, but the sparse within-host HIV-1 sampling prevents accurate quantification of the concomitant loss in genetic diversity. We draw inference under the transmission model to estimate HIV-1 evolutionary rates among epidemiologically-related patients and demonstrate that they lie in between fast intra-host rates and lower rates among epidemiologically unrelated individuals infected with HIV subtype C. Using a new molecular clock approach, we quantify and find support for a lower evolutionary rate along branches that accommodate a transmission event or branches that represent the entire backbone of transmitted lineages in our transmission history. Finally, we recover the rate differences at the different biological scales for both synonymous and non-synonymous substitution rates, which is only compatible with the ‘store and retrieve’ hypothesis positing that viruses stored early in latently infected cells

Where is, in 2017, the evo in evo-devo (evolutionary developmental biology)?

Science.gov (United States)

Diogo, Rui

2018-01-01

After the inaugural Pan-American-Evo-Devo meeting (2015, Berkeley), I showed how major concerns about evo-devo (Evolutionary Developmental Biology) research were demonstrated by a simple, non-biased quantitative analysis of the titles/abstracts of that meeting's talks. Here, I apply the same methodology to the titles/abstracts of the recent Pan-American-Evo-Devo meeting (2017, Calgary). The aim is to evaluate if the concerns raised by me in that paper and by other authors have been addressed and/or if there are other types of differences between the two meetings that may reflect trends within the field of evo-devo. This analysis shows that the proportion of presentations referring to "morphology", "organism", "selection", "adaptive", "phylogeny", and their derivatives was higher in the 2017 meeting, which therefore had a more "organismal" feel. However, there was a decrease in the use of "evolution"/its derivatives and of macroevolutionary terms related to the tempo and mode of evolution in the 2017 meeting. Moreover, the disproportionately high use of genetic/genomic terms clearly shows that evo-devo continues to be mainly focused on devo, and particularly on "Geno", that is, on molecular/genetic studies. Furthermore, the vast majority of animal evo-devo studies are focused only on hard tissues, which are just a small fraction of the whole organism-for example, only 15% of the tissue mass of the human body. The lack of an integrative approach is also evidenced by the lack of studies addressing conceptual/long-standing broader questions, including the links between ecology and particularly behavior and developmental/evolutionary variability and between evo-devo and evolutionary medicine. © 2018 Wiley Periodicals, Inc.

Tempo resposta de um serviço de atendimento móvel de urgência

OpenAIRE

Rosane Mortari Ciconet

2015-01-01

O tempo resposta é um indicador usado para avaliação da qualidade de serviços de atendimento pré-hospitalar (APH). Consiste no intervalo de tempo entre a expressão do pedido de socorro até a chegada da equipe à cena do evento. Assim, o objetivo do estudo foi analisar o tempo resposta de um SAMU, referente aos chamados para atendimentos clínicos e traumáticos demandados à Central de Regulação de Urgências. Os agravos clínicos foram compostos pelas síndromes neurológicas, cardiovasculares e res...

Evolutionary molecular medicine.

Science.gov (United States)

Nesse, Randolph M; Ganten, Detlev; Gregory, T Ryan; Omenn, Gilbert S

2012-05-01

Evolution has long provided a foundation for population genetics, but some major advances in evolutionary biology from the twentieth century that provide foundations for evolutionary medicine are only now being applied in molecular medicine. They include the need for both proximate and evolutionary explanations, kin selection, evolutionary models for cooperation, competition between alleles, co-evolution, and new strategies for tracing phylogenies and identifying signals of selection. Recent advances in genomics are transforming evolutionary biology in ways that create even more opportunities for progress at its interfaces with genetics, medicine, and public health. This article reviews 15 evolutionary principles and their applications in molecular medicine in hopes that readers will use them and related principles to speed the development of evolutionary molecular medicine.

Transparent bionanocomposite films based on chitosan and TEMPO-oxidized cellulose nanofibers with enhanced mechanical and barrier properties.

Science.gov (United States)

Soni, Bhawna; Hassan, El Barbary; Schilling, M Wes; Mahmoud, Barakat

2016-10-20

The development of biobased active films for use in food packaging is increasing due to low cost, environmental appeal, renewability and availability. The objective of this research was to develop an effective and complete green approach for the production of bionanocomposite films with enhanced mechanical and barrier properties. This was accomplished by incorporating TEMPO-oxidized cellulose nanofibers (2,2,6,6-tetramethylpiperidine-1-oxyl radical) into a chitosan matrix. An aqueous suspension of chitosan (100-75wt%), sorbitol (25wt%) and TEMPO-oxidized cellulose nanofibers (TEMPO-CNFs, 0-25wt%) were cast in an oven at 40°C for 2-4days. Films were preconditioned at 25°C and 50% RH for characterization. The surface morphology of the films was revealed by scanning electron microscopy (SEM) and atomic force microscopy (AFM). The thermal properties and crystal structure of the films were evaluated by thermogravimetric analysis (TGA-DTG) and X-ray diffraction (XRD). Incorporation of TEMPO-CNFs enhanced the mechanical strength of the films due to the high aspect ratio (3-20nm width, and 10-100nm length) of TEMPO-CNFs and strong interactions with the chitosan matrix. Oxygen and water vapor transmission rates for films that are prepared with chitosan and TEMPO-CNFs (15-25wt%) were significantly reduced. Furthermore, these bionanocomposite films had good thermal stability. Use of TEMPO-CNFs in this method makes it possible to produce bionanocomposite films that are flexible, transparent, and thus have potential in food packaging applications. Copyright © 2016 Elsevier Ltd. All rights reserved.

Regulatory RNA design through evolutionary computation and strand displacement.

Science.gov (United States)

Rostain, William; Landrain, Thomas E; Rodrigo, Guillermo; Jaramillo, Alfonso

2015-01-01

The discovery and study of a vast number of regulatory RNAs in all kingdoms of life over the past decades has allowed the design of new synthetic RNAs that can regulate gene expression in vivo. Riboregulators, in particular, have been used to activate or repress gene expression. However, to accelerate and scale up the design process, synthetic biologists require computer-assisted design tools, without which riboregulator engineering will remain a case-by-case design process requiring expert attention. Recently, the design of RNA circuits by evolutionary computation and adapting strand displacement techniques from nanotechnology has proven to be suited to the automated generation of DNA sequences implementing regulatory RNA systems in bacteria. Herein, we present our method to carry out such evolutionary design and how to use it to create various types of riboregulators, allowing the systematic de novo design of genetic control systems in synthetic biology.

Quantifying TEMPO Redox Polymer Charge Transport toward the Organic Radical Battery.

Science.gov (United States)

Karlsson, Christoffer; Suga, Takeo; Nishide, Hiroyuki

2017-03-29

To design new and better organic active battery materials in a rational fashion, fundamental parameters of the charge transport must be studied. Herein we report on the electronic conductivity by electron diffusion in a TEMPO-containing redox polymer, and the reorganization energy of the TEMPO self-exchange in an organic solvent is determined for the first time. The electronic conductivity was 8.5 μS/cm at E 0 and corresponded to a redox hopping mechanism. The apparent electron diffusion coefficient was 1.9 × 10 -9 cm 2 /s at room temperature, and at short times the ion diffusion was limiting with a diffusion coefficient of 6.5 × 10 -10 cm 2 /s. The reorganization energy was determined to be 1.01 eV, indicating a rather polar chemical environment for the TEMPO groups. The implications for the usage of this type of materials in organic energy storage are discussed. As conductivity through 10 μm was demonstrated, we show that, if sufficient swellability can be ensured, charge can be transported through several micrometer thick layers in a battery electrode without any conducting additive.

Tempo: A Toolkit for the Timed Input/Output Automata Formalism

National Research Council Canada - National Science Library

Lynch, Nancy A; Shvartsman, Alex Allister

2008-01-01

Report developed under STTR contract for topic AFO4-T023. This Phase II project developed an integrated development environment, called Tempo, for specifying, analyzing, and verifying complex distributed system designs...

Pengembangan alat tempo trainer untuk membantu efisiensi gerakan lengan gaya bebas cabang olahraga renang

Directory of Open Access Journals (Sweden)

Bahtiyar Heru Susanto

2017-09-01

This research aimed to develop the tools of Tempo Trainer to help efficiency of arm freestyle movement on the branch of swimming. Small-scale trials were conducted on four coaches and 10 athletes in the swimming association Tirta Alvita and Yuso. Large-scale trial was conducted on 10 coaches and 25 athletes in the swimming association Tirta Alvita, Yuso, Dolphin, Caesar, and Arowana. The instrument used to collect data was a questionnaire based on the analysis PIECES (Performance, Information, Economic, Control, Efficiency, Services. The assessment result of experts, coaches, and athletes toward Tempo Trainer tool shows that the assessment categoryis good, valid and reliable. Based of the resultsthat Tempo Trainer tool developed can count the number of cycles of freestyle movement, a sound that can be heard by coaches and athletes, can be used for more than one athlete, as well as it is more affordable. The coaches assessment shows valid results with every indicator PIECES obtain value rxy > r table = 0.632, with reliable results rxy = 0.908. The assessment of Tempo Trainer draft tool by athletes is good and valid with the result of the rxy > r table = 0.750.

Diálogos acerca da concepção de tempo homogêneo e heterogêneo em Einstein e Bergson

Directory of Open Access Journals (Sweden)

Lara Emanuele da Luz

2017-03-01

Full Text Available O problema sobre o tempo é um tema complexo e bastante estudado tanto no âmbito científico como na tradição filosófica. Henri Bergson, utilizando-se do tempo proposto por Albert Einstein, traça diferenças entre o tempo heterogêneo, ou cronológico, e o tempo homogêneo, ou durée, sendo este segundo, o menos estudado pelo físico. Foi a partir da duração que o filósofo propõe-se a mostrar como se dá a concepção do tempo durée e como esta forma responde a um questionamento einsteiniano. O presente artigo pretende estabelecer um diálogo entre a concepção de tempo de ambos autores, ressaltando a novidade da duração bergsoniana.

Quality management of cut carnation 'Tempo' with 1- MCP

African Journals Online (AJOL)

STORAGESEVER

2009-10-19

Oct 19, 2009 ... carnation 'Tempo' which is an ethylene-sensitive flower, were evaluated. The effects of 1-MCP .... rolling of the petals. Water uptake rate (ml g-1 .... The studies of Chamani (2006) on Rosa 'First red' cut flowers revealed that ...

Synchronization to metrical levels in music depends on low-frequency spectral components and tempo.

Science.gov (United States)

Burger, Birgitta; London, Justin; Thompson, Marc R; Toiviainen, Petri

2017-07-15

Previous studies have found relationships between music-induced movement and musical characteristics on more general levels, such as tempo or pulse clarity. This study focused on synchronization abilities to music of finely-varying tempi and varying degrees of low-frequency spectral change/flux. Excerpts from six classic Motown/R&B songs at three different tempos (105, 115, and 130 BPM) were used as stimuli in this experiment. Each was then time-stretched by a factor of 5% with regard to the original tempo, yielding a total of 12 stimuli that were presented to 30 participants. Participants were asked to move along with the stimuli while being recorded with an optical motion capture system. Synchronization analysis was performed relative to the beat and the bar level of the music and four body parts. Results suggest that participants synchronized different body parts to specific metrical levels; in particular, vertical movements of hip and feet were synchronized to the beat level when the music contained large amounts of low-frequency spectral flux and had a slower tempo, while synchronization of head and hands was more tightly coupled to the weak flux stimuli at the bar level. Synchronization was generally more tightly coupled to the slower versions of the same stimuli, while synchronization showed an inverted u-shape effect at the bar level as tempo increased. These results indicate complex relationships between musical characteristics, in particular regarding metrical and temporal structure, and our ability to synchronize and entrain to such musical stimuli.

catalysed selective oxidation of benzyl alcohols using TEMPO

Indian Academy of Sciences (India)

oxygen provides excellent results in terms of yields and reaction time. SiO2-Cu(II) was very ... lytic systems using transition metal complexes and ter- minal oxidants are well ... dry toluene, TEMPO (0.5 mmol), potassium carbonate. (1.5 mmol) and ... The conditioning of the catalyst was done in water, ethanol and toluene to.

Experiência subjetiva do tempo e sua influência no comportamento: revisão e modelos

Directory of Open Access Journals (Sweden)

Alejandro Vásquez Echeverría

Full Text Available Pesquisadores têm tentado explicar, desde o início da psicologia, a experiência temporal das pessoas e sua influência nas cognições, emoções e comportamentos. Trata-se de uma das dimensões mais complexas e influentes da psique, que tem sido abordada a partir de concepções diferentes e sem uma estrutura consensual. Este artigo tem o objetivo de contribuir na sistematização da psicologia do tempo, ampliando um modelo de quatro níveis, aprofundando na percepção do tempo vital ou tempo III. Trabalhos incluídos foram selecionados segundo a sua importância na historia da psicologia ou índice de citação. Sugere-se um modelo explicativo do Tempo III, que inclui discussão e debate e visa integrar os diferentes modelos existentes na literatura.

Top predators induce the evolutionary diversification of intermediate predator species.

Science.gov (United States)

Zu, Jian; Yuan, Bo; Du, Jianqiang

2015-12-21

We analyze the evolutionary branching phenomenon of intermediate predator species in a tritrophic food chain model by using adaptive dynamics theory. Specifically, we consider the adaptive diversification of an intermediate predator species that feeds on a prey species and is fed upon by a top predator species. We assume that the intermediate predator׳s ability to forage on the prey can adaptively improve, but this comes at the cost of decreased defense ability against the top predator. First, we identify the general properties of trade-off relationships that lead to a continuously stable strategy or to evolutionary branching in the intermediate predator species. We find that if there is an accelerating cost near the singular strategy, then that strategy is continuously stable. In contrast, if there is a mildly decelerating cost near the singular strategy, then that strategy may be an evolutionary branching point. Second, we find that after branching has occurred, depending on the specific shape and strength of the trade-off relationship, the intermediate predator species may reach an evolutionarily stable dimorphism or one of the two resultant predator lineages goes extinct. Crown Copyright © 2015. Published by Elsevier Ltd. All rights reserved.

Revealing spatio-spectral electroencephalographic dynamics of musical mode and tempo perception by independent component analysis.

Science.gov (United States)

Lin, Yuan-Pin; Duann, Jeng-Ren; Feng, Wenfeng; Chen, Jyh-Horng; Jung, Tzyy-Ping

2014-02-28

Music conveys emotion by manipulating musical structures, particularly musical mode- and tempo-impact. The neural correlates of musical mode and tempo perception revealed by electroencephalography (EEG) have not been adequately addressed in the literature. This study used independent component analysis (ICA) to systematically assess spatio-spectral EEG dynamics associated with the changes of musical mode and tempo. Empirical results showed that music with major mode augmented delta-band activity over the right sensorimotor cortex, suppressed theta activity over the superior parietal cortex, and moderately suppressed beta activity over the medial frontal cortex, compared to minor-mode music, whereas fast-tempo music engaged significant alpha suppression over the right sensorimotor cortex. The resultant EEG brain sources were comparable with previous studies obtained by other neuroimaging modalities, such as functional magnetic resonance imaging (fMRI) and positron emission tomography (PET). In conjunction with advanced dry and mobile EEG technology, the EEG results might facilitate the translation from laboratory-oriented research to real-life applications for music therapy, training and entertainment in naturalistic environments.

Tempo and walking speed with music in the urban context.

Science.gov (United States)

Franěk, Marek; van Noorden, Leon; Režný, Lukáš

2014-01-01

The study explored the effect of music on the temporal aspects of walking behavior in a real outdoor urban setting. First, spontaneous synchronization between the beat of the music and step tempo was explored. The effect of motivational and non-motivational music (Karageorghis et al., 1999) on the walking speed was also studied. Finally, we investigated whether music can mask the effects of visual aspects of the walking route environment, which involve fluctuation of walking speed as a response to particular environmental settings. In two experiments, we asked participants to walk around an urban route that was 1.8 km in length through various environments in the downtown area of Hradec Králové. In Experiment 1, the participants listened to a musical track consisting of world pop music with a clear beat. In Experiment 2, participants were walking either with motivational music, which had a fast tempo and a strong rhythm, or with non-motivational music, which was slower, nice music, but with no strong implication to movement. Musical beat, as well as the sonic character of the music listened to while walking, influenced walking speed but did not lead to precise synchronization. It was found that many subjects did not spontaneously synchronize with the beat of the music at all, and some subjects synchronized only part of the time. The fast, energetic music increases the speed of the walking tempo, while slower, relaxing music makes the walking tempo slower. Further, it was found that listening to music with headphones while walking can mask the influence of the surrounding environment to some extent. Both motivational music and non-motivational music had a larger effect than the world pop music from Experiment 1. Individual differences in responses to the music listened to while walking that were linked to extraversion and neuroticism were also observed. The findings described here could be useful in rhythmic stimulation for enhancing or recovering the features of

Tempo and walking speed with music in the urban context

Directory of Open Access Journals (Sweden)

Marek eFranek

2014-12-01

Full Text Available The study explored the effect of music on the temporal aspects of walking behavior in a real outdoor urban setting. First, spontaneous synchronization between the beat of the music and step tempo was explored. The effect of motivational and non-motivational music (Karageorghis et al. 1999 on the walking speed was also studied. Finally, we investigated whether music can mask the effects of visual aspects of the walking route environment, which involve fluctuation of walking speed as a response to particular environmental settings. In two experiments, we asked participants to walk around an urban route through various environments in the downtown area of Hradec Králové. In Experiment 1, the participants listened to a musical track consisting of world pop music with a clear beat. In Experiment 2, participants were walking either with motivational music, which had a fast tempo and a strong rhythm, or with non-motivational music, which was slower, nice music, but with no strong implication to movement. Musical beat, as well as the sonic character of the music listened to while walking, influenced walking speed but did not lead to precise synchronization. It was found that many subjects did not spontaneously synchronize with the beat of the music at all, and some subjects synchronized only part of the time. The fast, energetic music increases the speed of the walking tempo, while slower, relaxing music makes the walking tempo slower. Further, it was found that listening to music with headphones while walking can mask the influence of the surrounding environment to some extent. Both motivational music and non-motivational music had a larger effect than the music from Experiment 1. Individual differences in responses to the music listened to while walking that were linked to extraversion and neuroticism were also observed. The findings described here could be useful in rhythmic stimulation for enhancing or recovering the features of movement

Tempo and walking speed with music in the urban context

Science.gov (United States)

Franěk, Marek; van Noorden, Leon; Režný, Lukáš

2014-01-01

The study explored the effect of music on the temporal aspects of walking behavior in a real outdoor urban setting. First, spontaneous synchronization between the beat of the music and step tempo was explored. The effect of motivational and non-motivational music (Karageorghis et al., 1999) on the walking speed was also studied. Finally, we investigated whether music can mask the effects of visual aspects of the walking route environment, which involve fluctuation of walking speed as a response to particular environmental settings. In two experiments, we asked participants to walk around an urban route that was 1.8 km in length through various environments in the downtown area of Hradec Králové. In Experiment 1, the participants listened to a musical track consisting of world pop music with a clear beat. In Experiment 2, participants were walking either with motivational music, which had a fast tempo and a strong rhythm, or with non-motivational music, which was slower, nice music, but with no strong implication to movement. Musical beat, as well as the sonic character of the music listened to while walking, influenced walking speed but did not lead to precise synchronization. It was found that many subjects did not spontaneously synchronize with the beat of the music at all, and some subjects synchronized only part of the time. The fast, energetic music increases the speed of the walking tempo, while slower, relaxing music makes the walking tempo slower. Further, it was found that listening to music with headphones while walking can mask the influence of the surrounding environment to some extent. Both motivational music and non-motivational music had a larger effect than the world pop music from Experiment 1. Individual differences in responses to the music listened to while walking that were linked to extraversion and neuroticism were also observed. The findings described here could be useful in rhythmic stimulation for enhancing or recovering the features of

Emotional and psychophysiological responses to tempo, mode, and percussiveness

NARCIS (Netherlands)

van der Zwaag, Marjolein; Westerink, Joyce H.D.M.; van den Broek, Egon

People often listen to music to influence their emotional state. However, the specific musical characteristics which cause this process are not yet fully understood. We have investigated the influence of the musical characteristics of tempo, mode and percussiveness on our emotions. In a quest

Os Usos do Tempo Livre entre Jovens de Classes Populares

Directory of Open Access Journals (Sweden)

Manoela Pagotto Martins Nodari

Full Text Available RESUMO O presente estudo, de caráter quantitativo, pretendeu investigar aspectos relacionados ao tempo livre de jovens de classes populares. Participaram da pesquisa 291 jovens (53,3% meninas, de 15 a 19 anos (M = 16,3; DP = 1,09, estudantes de ensino médio em escolas públicas da Grande Vitória, ES. Os dados foram coletados através de questionário e analisados através do software SPSS. Os resultados apontaram, principalmente, para os diferentes fatores envolvidos nas formas de apropriação do tempo livre entre esses jovens, não relacionados estritamente à renda, mas também a aspectos como gênero, meio em que vivem, estilos de vida e grupos de que participam.

Does Listening to Slow Tempo Classical Music During Independent Writing Affect Children's On-Task Performance?

Science.gov (United States)

McKnight, Rosemary

This project explored the effects of slow tempo classical music on children's on-task performance during independent writing. The project sample consisted of 24 students from a first grade classroom in the New York City Public School System. The students' on-task behavior was observed with and without use of slow tempo classical music playing, and…

One-Step Cationic Grafting of 4-Hydroxy-TEMPO and its Application in a Hybrid Redox Flow Battery with a Crosslinked PBI Membrane.

Science.gov (United States)

Chang, Zhenjun; Henkensmeier, Dirk; Chen, Ruiyong

2017-08-24

By using a one-step epoxide ring-opening reaction between 4-hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl (4-hydroxy-TEMPO) and glycidyltrimethylammonium cation (GTMA + ), we synthesized a cation-grafted TEMPO (g + -TEMPO) and studied its electrochemical performance against a Zn 2+ /Zn anode in a hybrid redox flow battery. To conduct Cl - counter anions, a crosslinked methylated polybenzimidazole (PBI) membrane was prepared and placed between the catholyte and anolyte. Compared to 4-hydroxy-TEMPO, the positively charged g + - TEMPO exhibits enhanced reaction kinetics. Moreover, flow battery tests with g + -TEMPO show improved Coulombic, voltage, and energy efficiencies and cycling stability over 140 cycles. Crossover of active species through the membrane was not detected. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Evolutionary thinking

Science.gov (United States)

Hunt, Tam

2014-01-01

Evolution as an idea has a lengthy history, even though the idea of evolution is generally associated with Darwin today. Rebecca Stott provides an engaging and thoughtful overview of this history of evolutionary thinking in her 2013 book, Darwin's Ghosts: The Secret History of Evolution. Since Darwin, the debate over evolution—both how it takes place and, in a long war of words with religiously-oriented thinkers, whether it takes place—has been sustained and heated. A growing share of this debate is now devoted to examining how evolutionary thinking affects areas outside of biology. How do our lives change when we recognize that all is in flux? What can we learn about life more generally if we study change instead of stasis? Carter Phipps’ book, Evolutionaries: Unlocking the Spiritual and Cultural Potential of Science's Greatest Idea, delves deep into this relatively new development. Phipps generally takes as a given the validity of the Modern Synthesis of evolutionary biology. His story takes us into, as the subtitle suggests, the spiritual and cultural implications of evolutionary thinking. Can religion and evolution be reconciled? Can evolutionary thinking lead to a new type of spirituality? Is our culture already being changed in ways that we don't realize by evolutionary thinking? These are all important questions and Phipps book is a great introduction to this discussion. Phipps is an author, journalist, and contributor to the emerging “integral” or “evolutionary” cultural movement that combines the insights of Integral Philosophy, evolutionary science, developmental psychology, and the social sciences. He has served as the Executive Editor of EnlightenNext magazine (no longer published) and more recently is the co-founder of the Institute for Cultural Evolution, a public policy think tank addressing the cultural roots of America's political challenges. What follows is an email interview with Phipps. PMID:26478766

Individual differences in boys' and girls' timing and tempo of puberty: modeling development with nonlinear growth models.

Science.gov (United States)

Marceau, Kristine; Ram, Nilam; Houts, Renate M; Grimm, Kevin J; Susman, Elizabeth J

2011-09-01

Pubertal development is a nonlinear process progressing from prepubescent beginnings through biological, physical, and psychological changes to full sexual maturity. To tether theoretical concepts of puberty with sophisticated longitudinal, analytical models capable of articulating pubertal development more accurately, we used nonlinear mixed-effects models to describe both the timing and tempo of pubertal development in the sample of 364 White boys and 373 White girls measured across 6 years as part of the National Institute of Child Health and Human Development Study of Early Child Care and Youth Development. Individual differences in timing and tempo were extracted with models of logistic growth. Differential relations emerged for how boys' and girls' timing and tempo of development were related to physical characteristics (body mass index, height, and weight) and psychological outcomes (internalizing problems, externalizing problems, and risky sexual behavior). Timing and tempo are associated in boys but not girls. Pubertal timing and tempo are particularly important for predicting psychological outcomes in girls but only sparsely related to boys' psychological outcomes. Results highlight the importance of considering the nonlinear nature of puberty and expand the repertoire of possibilities for examining important aspects of how and when pubertal processes contribute to development.

Effects of Modeling and Tempo Patterns as Practice Techniques on the Performance of High School Instrumentalists.

Science.gov (United States)

Henley, Paul T.

2001-01-01

Examines the effect of modeling conditions and tempo patterns on high school instrumentalists' performance. Focuses on high school students (n=60) who play wind instruments. Reports that the with-model condition was superior in rhythm and tempo percentage gain when compared to the no-model condition. Includes references. (CMK)

Predictive and tempo-flexible synchronization to a visual metronome in monkeys.

Science.gov (United States)

Takeya, Ryuji; Kameda, Masashi; Patel, Aniruddh D; Tanaka, Masaki

2017-07-21

Predictive and tempo-flexible synchronization to an auditory beat is a fundamental component of human music. To date, only certain vocal learning species show this behaviour spontaneously. Prior research training macaques (vocal non-learners) to tap to an auditory or visual metronome found their movements to be largely reactive, not predictive. Does this reflect the lack of capacity for predictive synchronization in monkeys, or lack of motivation to exhibit this behaviour? To discriminate these possibilities, we trained monkeys to make synchronized eye movements to a visual metronome. We found that monkeys could generate predictive saccades synchronized to periodic visual stimuli when an immediate reward was given for every predictive movement. This behaviour generalized to novel tempi, and the monkeys could maintain the tempo internally. Furthermore, monkeys could flexibly switch from predictive to reactive saccades when a reward was given for each reactive response. In contrast, when humans were asked to make a sequence of reactive saccades to a visual metronome, they often unintentionally generated predictive movements. These results suggest that even vocal non-learners may have the capacity for predictive and tempo-flexible synchronization to a beat, but that only certain vocal learning species are intrinsically motivated to do it.

Manipulating Greek musical modes and tempo affects perceived musical emotion in musicians and nonmusicians

Directory of Open Access Journals (Sweden)

D. Ramos

2011-02-01

Full Text Available The combined influence of tempo and mode on emotional responses to music was studied by crossing 7 changes in mode with 3 changes in tempo. Twenty-four musicians aged 19 to 25 years (12 males and 12 females and 24 nonmusicians aged 17 to 25 years (12 males and 12 females were required to perform two tasks: 1 listening to different musical excerpts, and 2 associating an emotion to them such as happiness, serenity, fear, anger, or sadness. ANOVA showed that increasing the tempo strongly affected the arousal (F(2,116 = 268.62, mean square error (MSE = 0.6676, P < 0.001 and, to a lesser extent, the valence of emotional responses (F(6,348 = 8.71, MSE = 0.6196, P < 0.001. Changes in modes modulated the affective valence of the perceived emotions (F(6,348 = 4.24, MSE = 0.6764, P < 0.001. Some interactive effects were found between tempo and mode (F (1,58 = 115.6, MSE = 0.6428, P < 0.001, but, in most cases, the two parameters had additive effects. This finding demonstrates that small changes in the pitch structures of modes modulate the emotions associated with the pieces, confirming the cognitive foundation of emotional responses to music.

Effects of Tempo and Performing Medium on Children's Music Preference.

Science.gov (United States)

LeBlanc, Albert; Cote, Richard

1983-01-01

This study measured the effect of three levels of tempo and two levels of performing medium, vocal and instrumental, on the expressed preference of fifth- and sixth-grade students for traditional jazz music listening examples. (Author/SR)

Effects of tempo and timing of simple musical rhythms

NARCIS (Netherlands)

Repp, B.H.; Windsor, W.L.; Desain, P.W.M.

2002-01-01

In this study we investigated whether and how the timing of musical rhythms changes with tempo. Twelve skilled pianists played a monophonic 8-bar melody in 21 different rhythmic versions at 4 different tempi. Within bars, the rhythms represented all possible ordered pairs and triplets of note values

Oxidation of cashew tree gum exudate polysaccharide with TEMPO reagent

International Nuclear Information System (INIS)

Cunha, Pablyana L.R.; Maciel, Jeanny S.; Paula, Regina C.M. de; Feitosa, Judith P.A.; Sierakowski, Maria Rita

2007-01-01

Cashew gum (CG), an exudate polysaccharide from Anacardium occidentale trees, was oxidized with TEMPO reagent and the product (CGOX) characterized by spectroscopic techniques (FTIR and NMR), chromatographic analyses (HPLC and GPC), viscosity measurements and thermal analysis (TGA). The yield of the reaction product was 96%. The uronic acid content in starting gum (7.2 m%) was increased to 36 m%. The degree of oxidation based on free galactose and glucose units was 68%. NMR data show that oxidation occurred preferentially at primary carbons of galactose units. High degradation degree after oxidation was estimated by the difference on the expected and observed η CGOX /η CG ratio. The presence of organic and inorganic impurities in the new polyelectrolyte was detected by TGA. A less thermally stable cashew gum is formed after the oxidation with TEMPO based on initial decomposition temperature and IPDT. (author)

Evolutionary Stable Strategy

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 21; Issue 9. Evolutionary Stable Strategy: Application of Nash Equilibrium in Biology. General Article Volume 21 Issue 9 September 2016 pp 803- ... Keywords. Evolutionary game theory, evolutionary stable state, conflict, cooperation, biological games.

Effect of Music Tempo on Attentional Focus and Perceived Exertion during Self-selected Paced Walking.

Science.gov (United States)

Silva, Aldo Coelho; Dos Santos Ferreira, Sandro; Alves, Ragami Chaves; Follador, Lucio; DA Silva, Sergio Gregorio

2016-01-01

This study investigated the influence of music on the rating of perceived exertion (RPE) and attentional focus during walking at a self-selected pace. Fifteen overweight and obese women volunteered to participate in the study. They underwent four sessions: the first for incremental maximal test and anthropometric measurement followed by three experimental sessions. After the first session, they were exposed to three 30-minute walking sessions at a self-selected pace in a counterbalanced order: fast-tempo music (FT), medium-tempo music (MT) and no-music control (NM). Borg's RPE Scale and an Attentional Focus Questionnaire were used to measure the perceptual response and attentional focus, respectively. Results showed that the RPE was higher in the no-music control than in the medium-tempo music (12.05 ± 0.6 vs. 10.5 ± 0.5). Furthermore, dissociative attentional focus was greater for both conditions with music in comparison with the no-music control (NM= 39.0 ± 4.1; MT= 48.4 ± 4.1 and FT= 47.9 ± 4.5). The results indicated that the use of music during walking can modulate attentional focus, increasing dissociative thought, and medium-tempo music can reduce the RPE.

Gli incerti confini del cosmo dai buchi neri alle macchine del tempo

CERN Document Server

De Felice, Fernando

2000-01-01

Il libro mostra come la gravitazione abbia un ruolo determinante nei fenomeni cosmici che più ci impressionano, da quelli relativamente vicini alla nostra esperienza (come la formazione delle stelle) a quelli meno intuibili (come la formazione dei buchi neri), alla struttura dell'Universo nel suo insieme. Oltre a spiegare, in modo qualitativo, concetti come la geometria dello spazio-tempo, la relatività del tempo e i coni di luce, l'autore formula un'ipotesi innovativa tendente a spiegare l'origine della gravitazione e con essa quella dei fenomeni circondati ancora da un alone di mistero: la materia oscura dell'Universo e il destino della materia alla fine del collasso gravitazionale.

Cadernos encadeados: uma descrição sobre o encadeamento do tempo em uma turma alfabetizadora

Directory of Open Access Journals (Sweden)

Flávia Anastácio de Paula

Full Text Available Nas últimas duas décadas tem se discutido sobre as tematizações, as normatizações e as concretizações do tema alfabetização na escola. Entretanto, poucos são os trabalhos que se dedicam às concretizações do uso do tempo escolar para mediações alfabetizadoras que levem ao sucesso. Este artigo apresenta um dos modos de como se produzem usos do tempo por uma alfabetizadora experiente. Partindo de uma proposta metodológica etnográfica, escolhemos um elemento para descrição e compreensão: os cadernos. A problemática exemplifica um dos desafios na pesquisa em alfabetização: documentar práticas, artefatos, usos atuais (ou não significativos para as professoras no aprendizado da leitura e da escrita. A especificidade da análise adota algumas das dimensões de tempo elaboradas por Heller e recai sobre um aspecto da temporalidade: o encadeamento. Objetiva-se descrever e refletir sobre como professoras experientes organizam o tempo para ensinar.

Under pressure: evolutionary engineering of yeast strains for improved performance in fuels and chemicals production.

Science.gov (United States)

Mans, Robert; Daran, Jean-Marc G; Pronk, Jack T

2018-04-01

Evolutionary engineering, which uses laboratory evolution to select for industrially relevant traits, is a popular strategy in the development of high-performing yeast strains for industrial production of fuels and chemicals. By integrating whole-genome sequencing, bioinformatics, classical genetics and genome-editing techniques, evolutionary engineering has also become a powerful approach for identification and reverse engineering of molecular mechanisms that underlie industrially relevant traits. New techniques enable acceleration of in vivo mutation rates, both across yeast genomes and at specific loci. Recent studies indicate that phenotypic trade-offs, which are often observed after evolution under constant conditions, can be mitigated by using dynamic cultivation regimes. Advances in research on synthetic regulatory circuits offer exciting possibilities to extend the applicability of evolutionary engineering to products of yeasts whose synthesis requires a net input of cellular energy. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Early Adversity, Elevated Stress Physiology, Accelerated Sexual Maturation, and Poor Health in Females

Science.gov (United States)

Belsky, Jay; Ruttle, Paula L.; Boyce, W. Thomas; Armstrong, Jeffrey M.; Essex, Marilyn J.

2015-01-01

Evolutionary-minded developmentalists studying predictive-adaptive-response processes linking childhood adversity with accelerated female reproductive development and health scientists investigating the developmental origins of health and disease (DOoHaD) may be tapping the same process, whereby longer-term health costs are traded off for…

Scope and limitations of the TEMPO/EPR method for singlet oxygen detection: the misleading role of electron transfer.

Science.gov (United States)

Nardi, Giacomo; Manet, Ilse; Monti, Sandra; Miranda, Miguel A; Lhiaubet-Vallet, Virginie

2014-12-01

For many biological and biomedical studies, it is essential to detect the production of (1)O2 and quantify its production yield. Among the available methods, detection of the characteristic 1270-nm phosphorescence of singlet oxygen by time-resolved near-infrared (TRNIR) emission constitutes the most direct and unambiguous approach. An alternative indirect method is electron paramagnetic resonance (EPR) in combination with a singlet oxygen probe. This is based on the detection of the TEMPO free radical formed after oxidation of TEMP (2,2,6,6-tetramethylpiperidine) by singlet oxygen. Although the TEMPO/EPR method has been widely employed, it can produce misleading data. This is demonstrated by the present study, in which the quantum yields of singlet oxygen formation obtained by TRNIR emission and by the TEMPO/EPR method are compared for a set of well-known photosensitizers. The results reveal that the TEMPO/EPR method leads to significant overestimation of singlet oxygen yield when the singlet or triplet excited state of the photosensitizer is efficiently quenched by TEMP, acting as electron donor. In such case, generation of the TEMP(+) radical cation, followed by deprotonation and reaction with molecular oxygen, gives rise to an EPR-detectable TEMPO signal that is not associated with singlet oxygen production. This knowledge is essential for an appropriate and error-free application of the TEMPO/EPR method in chemical, biological, and medical studies. Copyright © 2014 Elsevier Inc. All rights reserved.

Music tempo estimation in dancing robot%舞蹈机器人中音乐节拍的识别

Institute of Scientific and Technical Information of China (English)

何晓亮

2013-01-01

音乐节拍是音乐的重要特征之一,对音乐节拍的提取是音乐识别的重要研究内容.小波变换方法可以实现对音乐节拍特征进行有效的提取与识别.文中对音乐节拍的分析采用双尺度小波变换(DWT)方法,即离散小波变换,提取音乐信号的自相关包络,对自相关包络信息进行分析,从而实现对音乐节拍信息的识别.实验证明,文中提出的方法可以有效地对音乐信号的节拍信息进行识别.%Music tempo is an important feature of music, Extraction of the tempo of music is an important research in music recognition. Wavelet transform can characteristics of music tempo extraction and identification effective. This paper analyzes the music tempo by two-scale wavelet transform (DWT) method, that is discrete wavelet transform. Extracted from the music signal, the autocorrelation envelope of music is analyzed in order to estimat the music tempo information. Experimental results show that the proposed method can effectively estimat music tempo information.

Heterostyly accelerates diversification via reduced extinction in primroses

Science.gov (United States)

de Vos, Jurriaan M.; Hughes, Colin E.; Schneeweiss, Gerald M.; Moore, Brian R.; Conti, Elena

2014-01-01

The exceptional species diversity of flowering plants, exceeding that of their sister group more than 250-fold, is especially evident in floral innovations, interactions with pollinators and sexual systems. Multiple theories, emphasizing flower–pollinator interactions, genetic effects of mating systems or high evolvability, predict that floral evolution profoundly affects angiosperm diversification. However, consequences for speciation and extinction dynamics remain poorly understood. Here, we investigate trajectories of species diversification focusing on heterostyly, a remarkable floral syndrome where outcrossing is enforced via cross-compatible floral morphs differing in placement of their respective sexual organs. Heterostyly evolved at least 20 times independently in angiosperms. Using Darwin's model for heterostyly, the primrose family, we show that heterostyly accelerates species diversification via decreasing extinction rates rather than increasing speciation rates, probably owing to avoidance of the negative genetic effects of selfing. However, impact of heterostyly appears to differ over short and long evolutionary time-scales: the accelerating effect of heterostyly on lineage diversification is manifest only over long evolutionary time-scales, whereas recent losses of heterostyly may prompt ephemeral bursts of speciation. Our results suggest that temporal or clade-specific conditions may ultimately determine the net effects of specific traits on patterns of species diversification. PMID:24759859

EvoluCode: Evolutionary Barcodes as a Unifying Framework for Multilevel Evolutionary Data.

Science.gov (United States)

Linard, Benjamin; Nguyen, Ngoc Hoan; Prosdocimi, Francisco; Poch, Olivier; Thompson, Julie D

2012-01-01

Evolutionary systems biology aims to uncover the general trends and principles governing the evolution of biological networks. An essential part of this process is the reconstruction and analysis of the evolutionary histories of these complex, dynamic networks. Unfortunately, the methodologies for representing and exploiting such complex evolutionary histories in large scale studies are currently limited. Here, we propose a new formalism, called EvoluCode (Evolutionary barCode), which allows the integration of different evolutionary parameters (eg, sequence conservation, orthology, synteny …) in a unifying format and facilitates the multilevel analysis and visualization of complex evolutionary histories at the genome scale. The advantages of the approach are demonstrated by constructing barcodes representing the evolution of the complete human proteome. Two large-scale studies are then described: (i) the mapping and visualization of the barcodes on the human chromosomes and (ii) automatic clustering of the barcodes to highlight protein subsets sharing similar evolutionary histories and their functional analysis. The methodologies developed here open the way to the efficient application of other data mining and knowledge extraction techniques in evolutionary systems biology studies. A database containing all EvoluCode data is available at: http://lbgi.igbmc.fr/barcodes.

Oxidation of cashew tree gum exudate polysaccharide with TEMPO reagent

Energy Technology Data Exchange (ETDEWEB)

Cunha, Pablyana L.R.; Maciel, Jeanny S.; Paula, Regina C.M. de; Feitosa, Judith P.A. [Universidade Federal do Ceara, Fortaleza, CE (Brazil). Dept. de Quimica Organica e Inorganica; Sierakowski, Maria Rita [Universidade Federal do Parana, Curitiba, PR (Brazil). Dept. de Quimica]. E-mail: judith@dqoi.ufc.br

2007-07-01

Cashew gum (CG), an exudate polysaccharide from Anacardium occidentale trees, was oxidized with TEMPO reagent and the product (CGOX) characterized by spectroscopic techniques (FTIR and NMR), chromatographic analyses (HPLC and GPC), viscosity measurements and thermal analysis (TGA). The yield of the reaction product was 96%. The uronic acid content in starting gum (7.2 m%) was increased to 36 m%. The degree of oxidation based on free galactose and glucose units was 68%. NMR data show that oxidation occurred preferentially at primary carbons of galactose units. High degradation degree after oxidation was estimated by the difference on the expected and observed {eta}{sub CGOX}/{eta}{sub CG} ratio. The presence of organic and inorganic impurities in the new polyelectrolyte was detected by TGA. A less thermally stable cashew gum is formed after the oxidation with TEMPO based on initial decomposition temperature and IPDT. (author)

CONSIDERAÇÕES SOBRE LAZER, TRABALHO E TEMPO LIVRE

Directory of Open Access Journals (Sweden)

Luiz César Teixeira dos Santos

2008-06-01

Full Text Available O objetivo deste trabalho é discutir o lazer a partir dos conceitos de trabalho e tempo livre. O tema é abordado com base em estudos recentes que tratam os assuntos relacionados ao lazer em uma perspectiva que sugere, mediante o crescente nível do desemprego em escala global, um aumento significativo do tempo livre do trabalhador. Rifkin (1995, ao tratar da questão do fim do emprego, aponta para um cenário onde milhares de trabalhadores se colocam favoráveis a uma maior disponibilidade para a família e o lazer, ainda que isso signifique uma redução dos níveis de renda. O mesmo autor, no entanto, descortina um sério problema para as futuras gerações, uma vez que, com o declínio das ofertas de emprego, um número maior de homens, sem trabalho (e em conseqüência disso, sem condições materiais tendem a uma situação de miserabilidade, onde a própria condição para o lazer se vê comprometida. Dessa forma, verifica-se que há uma potencialização para a prática do lazer que nem sempre se concretiza, pois as possibilidades para sua efetiva realização não se expandem em proporções similares ao aumento do tempo livre. A temática do lazer se insere ainda em um contexto onde o apelo ao consumo se tornou o principal protagonista da história do mundo contemporâneo. Por isso, o próprio lazer passou a ser visto como uma mercadoria em potencial e, enquanto tal, sujeito às frias e duras regras do mercado.

Spontaneous movement tempo is influenced by observation of rhythmical actions.

Science.gov (United States)

Bove, Marco; Tacchino, Andrea; Pelosin, Elisa; Moisello, Clara; Abbruzzese, Giovanni; Ghilardi, M Felice

2009-09-28

Observation of people performing movements facilitates motor planning, execution and memory formation. Tempo, a crucial aspect involved in the execution of rhythmic movements, is normally perceived and learned through auditory channels. In this work, we ascertained whether: first, the frequency of self-paced finger movements (SPMs), which in normal subjects is around 2 Hz, is modified by prior observation of movements performed at either 1 or 3 Hz; second, such changes are lasting; third, there is an effect of time interval between observation and performance. We finally determined the effect of providing explicit information about the upcoming motor task. Seventy-two normal subjects (12 groups) performed a simple finger sequence at different intervals after observation of videos of either landscapes or finger opposition movements. Both with and without information about the upcoming task, observation influenced the tempo of SPMs and led to memory formation. With knowledge of the upcoming task, such changes occurred at all observation-execution intervals, while without instructions, changes took place only when SPMs were performed immediately after observation. Compared to explicit instructions, the absence of instructions produced tempo's changes that more closely resembled the observed rhythms. We conclude that learning requires a prompt comparison between visual and sensorimotor representations of movements; moreover, learning with explicit instructions is more efficient, as activity in both the dorsal and ventral streams might be potentiated by the chatecholaminergic attentional systems that promote long-term potentiation. These results provide the bases for novel neurorehabilitation strategies in terms of temporal re-organization of movement.

Unidirectional adaptation in tempo in pairs of chimpanzees during simultaneous tapping movement: an examination under face-to-face setup.

Science.gov (United States)

Yu, Lira; Tomonaga, Masaki

2016-04-01

Many studies have reported a spontaneous nature to synchronized movement in humans and in non-human primates. However, it is not yet clear whether individuals mutually adapt their movement to each other or whether one individual significantly changes to synchronize with the other. In the current study, we examined a directionality of the tempo adaptation to understand an introductive process of interactional synchrony in pairs of chimpanzees. Four pairs, consisting of five female chimpanzees, produced a finger-tapping movement under a face-to-face experimental setup where both auditory and visual cues of the partner's movement were available. Two test conditions were prepared: alone and paired. An analysis of the tapping tempo depending on condition showed that only one chimpanzee in each pair significantly changed their tapping tempo in the direction of the partner's tapping tempo in the paired condition compared with the alone condition. The current study demonstrated that unidirectional adaptation in tempo occurs in pairs of chimpanzees when they simultaneously produce the tapping movement under auditory and visual interaction.

Effect of Music Tempo on Attentional Focus and Perceived Exertion during Self-selected Paced Walking

Science.gov (United States)

SILVA, ALDO COELHO; DOS SANTOS FERREIRA, SANDRO; ALVES, RAGAMI CHAVES; FOLLADOR, LUCIO; DA SILVA, SERGIO GREGORIO

2016-01-01

This study investigated the influence of music on the rating of perceived exertion (RPE) and attentional focus during walking at a self-selected pace. Fifteen overweight and obese women volunteered to participate in the study. They underwent four sessions: the first for incremental maximal test and anthropometric measurement followed by three experimental sessions. After the first session, they were exposed to three 30-minute walking sessions at a self-selected pace in a counterbalanced order: fast-tempo music (FT), medium-tempo music (MT) and no-music control (NM). Borg’s RPE Scale and an Attentional Focus Questionnaire were used to measure the perceptual response and attentional focus, respectively. Results showed that the RPE was higher in the no-music control than in the medium-tempo music (12.05 ± 0.6 vs. 10.5 ± 0.5). Furthermore, dissociative attentional focus was greater for both conditions with music in comparison with the no-music control (NM= 39.0 ± 4.1; MT= 48.4 ± 4.1 and FT= 47.9 ± 4.5). The results indicated that the use of music during walking can modulate attentional focus, increasing dissociative thought, and medium-tempo music can reduce the RPE. PMID:27990220

A medida do tempo: intuição e inteligência em Bergson

OpenAIRE

Monteiro, Geovana da Paz

2008-01-01

110f. Investigar a natureza do tempo real é, de acordo com Henri Bergson, perscrutar um objeto fugidio, uma vez que, ao tentarmos apreendê-lo, já se escoou em seu fluxo contínuo. Caberia à consciência compreendê-lo na passagem que lhe é própria. Doravante, uma dificuldade se mostra ao filósofo: tempo e espaço, sendo qualitativamente distintos, aparecem, quer para a filosofia, quer para a ciência, como faces de uma mesma moeda. O pensamento bergsoniano percebe, então, na espacialização do t...

Fronteiras, violência e o trabalho do tempo: alguns temas wittgensteinianos

Directory of Open Access Journals (Sweden)

Das Veena

1999-01-01

Full Text Available Trabalhos recentes sugerem que, quando se contempla a violência, atinge-se uma espécie de limite da capacidade de representar. O caso da Partição da Índia, em 1947, fornece um desses "dramas de horror", por seus atos hediondos de grande escala. Este ensaio trata da domesticação da violência, atualizada na história de uma família urbana do Punjabi, e da necessidade do "trabalho do tempo" para permitir sua cicatrização. Recuperando idéias de Wittgenstein para a Antropologia, a autora mostra como o trabalho do tempo, não sua imagem ou representação, serve para testar o sentido do que é humano quando a linguagem falha ou simplesmente não existe.

The Effects of Learning Procedure, Tempo, and Performance Condition on Transfer of Rhythm Skills in Instrumental Music.

Science.gov (United States)

Pierce, Michael A.

1992-01-01

Describes study of effects of learning procedures and performance tempo on ability of 64 middle school students to perform previously learned rhythmic passages. Reviews the four learning procedures used for each rhythmic passage. Finds no evidence attributed to learning procedure but significant adverse differences if the tempo was changed from…

TEMPO E FILOSOFIA NO ROMANCE "PEDRO PÁRAMO", DE JUÁN RULFO

Directory of Open Access Journals (Sweden)

Profª Drª Cláudia Falluh Balduino Ferreira

2012-01-01

Full Text Available Considerando que a questão filosófica expressa pela composição narrativa visa às relações e as tensões entre o tempo da narrativa e o da vida, e que várias disciplinas são convocadas a este amplo debate, o presente artigo quer ilustrar ao modo como se dão a aliança entre os processos mnemônicos e de anamnese e a experiência do tempo no romance do escritor mexicano Ruan Rulfo, empregando as noções filosóficas de anamnese conforme Platão e a questão do temporal segundo Paul Ricoeur.

Human brain basis of musical rhythm perception: common and distinct neural substrates for meter, tempo, and pattern.

Science.gov (United States)

Thaut, Michael H; Trimarchi, Pietro Davide; Parsons, Lawrence M

2014-06-17

Rhythm as the time structure of music is composed of distinct temporal components such as pattern, meter, and tempo. Each feature requires different computational processes: meter involves representing repeating cycles of strong and weak beats; pattern involves representing intervals at each local time point which vary in length across segments and are linked hierarchically; and tempo requires representing frequency rates of underlying pulse structures. We explored whether distinct rhythmic elements engage different neural mechanisms by recording brain activity of adult musicians and non-musicians with positron emission tomography (PET) as they made covert same-different discriminations of (a) pairs of rhythmic, monotonic tone sequences representing changes in pattern, tempo, and meter, and (b) pairs of isochronous melodies. Common to pattern, meter, and tempo tasks were focal activities in right, or bilateral, areas of frontal, cingulate, parietal, prefrontal, temporal, and cerebellar cortices. Meter processing alone activated areas in right prefrontal and inferior frontal cortex associated with more cognitive and abstract representations. Pattern processing alone recruited right cortical areas involved in different kinds of auditory processing. Tempo processing alone engaged mechanisms subserving somatosensory and premotor information (e.g., posterior insula, postcentral gyrus). Melody produced activity different from the rhythm conditions (e.g., right anterior insula and various cerebellar areas). These exploratory findings suggest the outlines of some distinct neural components underlying the components of rhythmic structure.

Oficinas de Gestão do Tempo com Estudantes Universitários

Directory of Open Access Journals (Sweden)

Clarissa Tochetto de Oliveira

Full Text Available Resumo Buscou-se descrever a experiência de oficinas de gestão do tempo realizadas junto a acadêmicos de uma universidade pública no interior do Rio Grande do Sul. Foram realizados oito encontros com o objetivo de avaliar e discutir a forma como os participantes costumam organizar o seu tempo. Participaram 85 alunos de graduação e pós-graduação. Os tópicos abordados incluíram estratégias utilizadas para organização, identificação de problemas, metas e objetivos e oferecimento de dicas. Foram descritos os procedimentos e as ferramentas utilizadas nas oficinas. As dificuldades vivenciadas pelos estudantes estavam relacionadas à procrastinação, à incapacidade de dizer “não” às demandas alheias, à carga horária de seus cursos e à conciliação entre estudos, convivência familiar e lazer. A participação na oficina foi um primeiro momento de reflexão sobre a temática para muitos participantes. Pesquisas que investiguem os “motivos” das dificuldades na gestão do tempo nessa população podem subsidiar futuras intervenções junto a esse público.

Does expressive timing in music performance scale proportionally with tempo?

NARCIS (Netherlands)

Desain, P.; Honing, H.

1994-01-01

Evidence is presented that expressive timing in music is not relationally invariant with global tempo. Our results stem from an analysis of repeated performances of Beethoven's variations on a Paisiello theme. Recordings were made of two pianists playing the pieces at three tempi. In contrast with

Effects of music tempo upon submaximal cycling performance.

Science.gov (United States)

Waterhouse, J; Hudson, P; Edwards, B

2010-08-01

In an in vivo laboratory controlled study, 12 healthy male students cycled at self-chosen work-rates while listening to a program of six popular music tracks of different tempi. The program lasted about 25 min and was performed on three occasions--unknown to the participants, its tempo was normal, increased by 10% or decreased by 10%. Work done, distance covered and cadence were measured at the end of each track, as were heart rate and subjective measures of exertion, thermal comfort and how much the music was liked. Speeding up the music program increased distance covered/unit time, power and pedal cadence by 2.1%, 3.5% and 0.7%, respectively; slowing the program produced falls of 3.8%, 9.8% and 5.9%. Average heart rate changes were +0.1% (faster program) and -2.2% (slower program). Perceived exertion and how much the music was liked increased (faster program) by 2.4% and 1.3%, respectively, and decreased (slower program) by 3.6% and 35.4%. That is, healthy individuals performing submaximal exercise not only worked harder with faster music but also chose to do so and enjoyed the music more when it was played at a faster tempo. Implications of these findings for improving training regimens are discussed.

Tempo, ciência e consenso: os diferentes tempos que envolvem a pesquisa científica, a decisão política e a opinião pública

Directory of Open Access Journals (Sweden)

José Aparecido de Oliveira

2009-06-01

Full Text Available Este trabalho analisa a assimétrica relação entre o tempo da pesquisa científica e o tempo dos diferentes segmentos interessados em seus resultados, sobretudo com a crescente demanda de se construir consenso técnico sobre campos da ciência que exigem rigorosas investigações e exaustivos testes. Destacam-se, sobretudo nos últimos anos, as pressões de setores da sociedade civil, interessados em participar do processo decisório que orienta os rumos da ciência, entre eles: o jornalismo científico, o poder legislativo e a opinião pública. Como exemplo, foi analisado o processo decisório do projeto de Lei de Biossegurança, que permite pesquisas com células-tronco embrionárias no Brasil. Os resultados permitem concluir que essa relação assimétrica entre os diferentes tempos (da ciência, da divulgação científica, da opinião pública e do poder público contribui para o amadurecimento do diálogo sobre política científica e a construção de consenso sobre os rumos da ciência, com vistas a democratizar o fazer científico.

Tempo, ciência e consenso: os diferentes tempos que envolvem a pesquisa científica, a decisão política e a opinião pública

Directory of Open Access Journals (Sweden)

José Aparecido de Oliveira

Full Text Available Este trabalho analisa a assimétrica relação entre o tempo da pesquisa científica e o tempo dos diferentes segmentos interessados em seus resultados, sobretudo com a crescente demanda de se construir consenso técnico sobre campos da ciência que exigem rigorosas investigações e exaustivos testes. Destacam-se, sobretudo nos últimos anos, as pressões de setores da sociedade civil, interessados em participar do processo decisório que orienta os rumos da ciência, entre eles: o jornalismo científico, o poder legislativo e a opinião pública. Como exemplo, foi analisado o processo decisório do projeto de Lei de Biossegurança, que permite pesquisas com células-tronco embrionárias no Brasil. Os resultados permitem concluir que essa relação assimétrica entre os diferentes tempos (da ciência, da divulgação científica, da opinião pública e do poder público contribui para o amadurecimento do diálogo sobre política científica e a construção de consenso sobre os rumos da ciência, com vistas a democratizar o fazer científico.

La liberazione del tempo

CERN Document Server

Selleri, Franco

2003-01-01

Negli ultimi dieci anni ho lavorato alla descrizione dei fenomeni naturali da parte di osservatori in movimento. E' un problema che molti credono risolto una volta per tutte dalle trasformazioni di Lorentz della teoria della relatività speciale (TRS nel seguito), ma che in realtà era rimasto aperto per una serie di ragioni che esporrò. Sento di dover dire che ho trovato risultati molto importanti, anche se il giudizio finale sul loro valore non può certo essere il mio. Infatti la conclusione di questa ricerca è duplice: una spiegazione dei dati empirici migliore di quella relativistica, e l'eliminazione di quegli aspetti della TRS che fanno a pugni con il buon senso; il tutto grazie alla liberazione del tempo dall'asservimento alle coordinate spaziali cui era stato costretto nello spazio a quattro dimensioni di Minkowski. La faccenda è raccontata con dovizia di particolari in un libro recente [FS]. Nel presente articolo espongo gli aspetti salienti della ricerca lasciando da parte quelli matematici.

Synthesis and properties of novel TEMPO-contained polypyrrole derivatives as the cathode material of organic radical battery

International Nuclear Information System (INIS)

Xu, Lihuan; Yang, Fang; Su, Chang; Ji, Lvlv; Zhang, Cheng

2014-01-01

Two 2,2,6,6-tetramethylpiperidinyl-N-oxy (TEMPO) contained polypyrrole (PPy) derivatives with the different side-chain length were synthesized by esterification of 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl free radial with pyrrole butyric acid and pyrrole caproic acid. Then the homopolymers of 4-(3-(Pyrrol-1-yl)butyryloxy)-2,2,6,6-tetramethylpiperidin-1-yloxy (PPy-B-TEMPO) and 4-(3-(Pyrrol-1-yl)hexanoyloxy)-2,2,6,6-tetramethylpiperidin-1-yloxy (PPy-C-TEMPO) were prepared by chemical oxidative polymerization. The structure, morphology, electrochemical properties of prepared polymers were characterized by fourier transform infrared spectroscopy (FTIR), ultraviolet visible spectroscopy (UV-vis), scanning electron microscopy (SEM), cyclic voltammograms (CV) and electrochemical impedance spectra (EIS), respectively. Also, the charge-discharge properties of the prepared polymers were studied by galvanostatic charge-discharge testing. The results demonstrated that the as-synthesized nitroxide radical polymers showed a reversible two-electron redox reaction process in the potential limits of 2.5–3.0 V and 3.4–3.8 V vs Li/Li + , respectively. Under our experimental conditions, PPy only presented the discharge capacity of 16.5 mAh·g −1 at 20 mA·g −1 between 2.5 and 4.2 V, while PPy-B-TEMPO with the short side-chain linked to TEMPO groups exhibited an initial discharge capacity of up to 86.5 mAh·g −1 with two well-defined plateaus. Furthermore, the PPy-C-TEMPO with the longer linking side-chain even displayed a discharge capacity of 115 mAh·g −1 . These superior electrochemical performances were ascribed to the flexible linking side-chain and the introduction of stable conductive PPy main chain, which benefits the improvement of charge carrier transportation in the aggregated polymer bulk

Development and Lability in the Parent-Child Relationship During Adolescence: Associations With Pubertal Timing and Tempo

Science.gov (United States)

Marceau, Kristine; Ram, Nilam; Susman, Elizabeth

2014-01-01

Adolescents' and parents' reactions to pubertal development are hypothesized to contribute to changes in family dynamics. Using 7-year longitudinal data from the NICHD-SECCYD (488 boys, 475 girls) we examined relations between pubertal development (timing, tempo) and trajectories (developmental change and year-to-year lability) of parent-child conflict and closeness from age 8.5 to 15.5 years. Changes were mostly characterized by year-to-year fluctuations – lability. Parent-child conflict increased and closeness decreased some with age. Pubertal timing and tempo were more consistently associated with lability in parent-child relationships than with long-term trends, although faster tempo was associated with steeper decreases in parent-child closeness. Findings provide a platform for examining how puberty contributes to both long-term and transient changes in adolescents' relationships and adjustment. PMID:26321856

North American pollution measurements from geostationary orbit with Tropospheric Emissions: Monitoring of Pollution (TEMPO)

Science.gov (United States)

Chance, K.

2017-12-01

TEMPO is the first NASA Earth Venture Instrument. It launches between 2019 and 2021 to measure atmospheric pollution from Mexico City and Cuba to the Canadian oil sands, and from the Atlantic to the Pacific, hourly at high spatial resolution, 10 km2. Geostationary daytime measurements capture the variability in the diurnal cycle of emissions and chemistry at sub-urban scale to improve emission inventories, monitor population exposure, and enable emission-control strategies.TEMPO measures UV/visible Earth reflectance spectra to retrieve O3, NO2, SO2, H2CO, C2H2O2, H2O, BrO, OClO, IO, aerosols, cloud parameters, and UVB radiation. It tracks aerosol loading. It provides near-real-time air quality products. TEMPO is the North American component of the upcoming the global geostationary constellation for pollution monitoring, together with the European Sentinel-4 and the Korean Geostationary Environmental Monitoring Spectrometer (GEMS).TEMPO science studies include: Intercontinental pollution transport; Solar-induced fluorescence from chlorophyll over land and in the ocean to study tropical dynamics, primary productivity and carbon uptake, to detect red tides, and to study phytoplankton; measurements of stratospheric intrusions that cause air quality exceedances; measurements at peaks in vehicle travel to capture the variability in emissions from mobile sources; measurements of thunderstorm activity, including outflow regions to better quantify lightning NOx and O3 production; cropland measurements to follow the temporal evolution of emissions after fertilizer application and from rain-induced emissions from semi-arid soils; investigating the chemical processing of primary fire emissions and the secondary formation of VOCs and ozone; examining ocean halogen emissions and their impact on the oxidizing capacity of coastal environments; measuring spectra of nighttime lights as markers for human activity, energy conservation, and compliance with outdoor lighting standards

Adaptabilidade do tempo de trabalho, banco de horas e horário concentrado

OpenAIRE

Verdasca, Daniela Vieira

2017-01-01

No presente trabalho pretendemos analisar os regimes de adaptabilidade, banco de horas e horário concentrado, bem como ponderar a sua contribuição para os princípios sempre presentes na temática da duração do trabalho, que por vezes se revelam antagónicos: a proteção do trabalhador, a tutela da sua saúde e da sua vida familiar e pessoal, uma vez que estes mecanismos permitem a variação do tempo de trabalho e logo dos tempos de não trabalho, e a salvaguarda dos interesses de gestão, sendo que ...

The effects of tempo and familiarity on children's affective interpretation of music.

Science.gov (United States)

Mote, Jasmine

2011-06-01

When and how does one learn to associate emotion with music? This study attempted to address this issue by examining whether preschool children use tempo as a cue in determining whether a song is happy or sad. Instrumental versions of children's songs were played at different tempos to adults and children ages 3 to 5 years. Familiar and unfamiliar songs were used to examine whether familiarity affected children's identification of emotion in music. The results indicated that adults, 4 year olds and 5 year olds rated fast songs as significantly happier than slow songs. However, 3 year olds failed to rate fast songs differently than slow songs at above-chance levels. Familiarity did not significantly affect children's identification of happiness and sadness in music.

Polymorphic Evolutionary Games.

Science.gov (United States)

Fishman, Michael A

2016-06-07

In this paper, I present an analytical framework for polymorphic evolutionary games suitable for explicitly modeling evolutionary processes in diploid populations with sexual reproduction. The principal aspect of the proposed approach is adding diploid genetics cum sexual recombination to a traditional evolutionary game, and switching from phenotypes to haplotypes as the new game׳s pure strategies. Here, the relevant pure strategy׳s payoffs derived by summing the payoffs of all the phenotypes capable of producing gametes containing that particular haplotype weighted by the pertinent probabilities. The resulting game is structurally identical to the familiar Evolutionary Games with non-linear pure strategy payoffs (Hofbauer and Sigmund, 1998. Cambridge University Press), and can be analyzed in terms of an established analytical framework for such games. And these results can be translated into the terms of genotypic, and whence, phenotypic evolutionary stability pertinent to the original game. Copyright © 2016 Elsevier Ltd. All rights reserved.

Remembering the evolutionary Freud.

Science.gov (United States)

Young, Allan

2006-03-01

Throughout his career as a writer, Sigmund Freud maintained an interest in the evolutionary origins of the human mind and its neurotic and psychotic disorders. In common with many writers then and now, he believed that the evolutionary past is conserved in the mind and the brain. Today the "evolutionary Freud" is nearly forgotten. Even among Freudians, he is regarded to be a red herring, relevant only to the extent that he diverts attention from the enduring achievements of the authentic Freud. There are three ways to explain these attitudes. First, the evolutionary Freud's key work is the "Overview of the Transference Neurosis" (1915). But it was published at an inopportune moment, forty years after the author's death, during the so-called "Freud wars." Second, Freud eventually lost interest in the "Overview" and the prospect of a comprehensive evolutionary theory of psychopathology. The publication of The Ego and the Id (1923), introducing Freud's structural theory of the psyche, marked the point of no return. Finally, Freud's evolutionary theory is simply not credible. It is based on just-so stories and a thoroughly discredited evolutionary mechanism, Lamarckian use-inheritance. Explanations one and two are probably correct but also uninteresting. Explanation number three assumes that there is a fundamental difference between Freud's evolutionary narratives (not credible) and the evolutionary accounts of psychopathology that currently circulate in psychiatry and mainstream journals (credible). The assumption is mistaken but worth investigating.

The Effect of Articulation Style on Perception of Modulated Tempo

Science.gov (United States)

Geringer, John M.; Madsen, Clifford K.; MacLeod, Rebecca B.; Kevin Droe

2006-01-01

We investigated the effect of legato and staccato articulation styles on the perception of modulated tempos. Ninety music majors served as participants. Listeners heard music examples that had been selected from two pieces, each of which included staccato and legato passages. Excerpts were presented to listeners in three conditions of tempo…

Understanding the mind from an evolutionary perspective: an overview of evolutionary psychology.

Science.gov (United States)

Shackelford, Todd K; Liddle, James R

2014-05-01

The theory of evolution by natural selection provides the only scientific explanation for the existence of complex adaptations. The design features of the brain, like any organ, are the result of selection pressures operating over deep time. Evolutionary psychology posits that the human brain comprises a multitude of evolved psychological mechanisms, adaptations to specific and recurrent problems of survival and reproduction faced over human evolutionary history. Although some mistakenly view evolutionary psychology as promoting genetic determinism, evolutionary psychologists appreciate and emphasize the interactions between genes and environments. This approach to psychology has led to a richer understanding of a variety of psychological phenomena, and has provided a powerful foundation for generating novel hypotheses. Critics argue that evolutionary psychologists resort to storytelling, but as with any branch of science, empirical testing is a vital component of the field, with hypotheses standing or falling with the weight of the evidence. Evolutionary psychology is uniquely suited to provide a unifying theoretical framework for the disparate subdisciplines of psychology. An evolutionary perspective has provided insights into several subdisciplines of psychology, while simultaneously demonstrating the arbitrary nature of dividing psychological science into such subdisciplines. Evolutionary psychologists have amassed a substantial empirical and theoretical literature, but as a relatively new approach to psychology, many questions remain, with several promising directions for future research. For further resources related to this article, please visit the WIREs website. The authors have declared no conflicts of interest for this article. © 2014 John Wiley & Sons, Ltd.

Musicians are more consistent: Gestural cross-modal mappings of pitch, loudness and tempo in real-time.

Science.gov (United States)

Küssner, Mats B; Tidhar, Dan; Prior, Helen M; Leech-Wilkinson, Daniel

2014-01-01

Cross-modal mappings of auditory stimuli reveal valuable insights into how humans make sense of sound and music. Whereas researchers have investigated cross-modal mappings of sound features varied in isolation within paradigms such as speeded classification and forced-choice matching tasks, investigations of representations of concurrently varied sound features (e.g., pitch, loudness and tempo) with overt gestures-accounting for the intrinsic link between movement and sound-are scant. To explore the role of bodily gestures in cross-modal mappings of auditory stimuli we asked 64 musically trained and untrained participants to represent pure tones-continually sounding and concurrently varied in pitch, loudness and tempo-with gestures while the sound stimuli were played. We hypothesized musical training to lead to more consistent mappings between pitch and height, loudness and distance/height, and tempo and speed of hand movement and muscular energy. Our results corroborate previously reported pitch vs. height (higher pitch leading to higher elevation in space) and tempo vs. speed (increasing tempo leading to increasing speed of hand movement) associations, but also reveal novel findings pertaining to musical training which influenced consistency of pitch mappings, annulling a commonly observed bias for convex (i.e., rising-falling) pitch contours. Moreover, we reveal effects of interactions between musical parameters on cross-modal mappings (e.g., pitch and loudness on speed of hand movement), highlighting the importance of studying auditory stimuli concurrently varied in different musical parameters. Results are discussed in light of cross-modal cognition, with particular emphasis on studies within (embodied) music cognition. Implications for theoretical refinements and potential clinical applications are provided.

The speed of our mental soundtracks: Tracking the tempo of involuntary musical imagery in everyday life.

Science.gov (United States)

Jakubowski, Kelly; Farrugia, Nicolas; Halpern, Andrea R; Sankarpandi, Sathish K; Stewart, Lauren

2015-11-01

The study of spontaneous and everyday cognitions is an area of rapidly growing interest. One of the most ubiquitous forms of spontaneous cognition is involuntary musical imagery (INMI), the involuntarily retrieved and repetitive mental replay of music. The present study introduced a novel method for capturing temporal features of INMI within a naturalistic setting. This method allowed for the investigation of two questions of interest to INMI researchers in a more objective way than previously possible, concerning (1) the precision of memory representations within INMI and (2) the interactions between INMI and concurrent affective state. Over the course of 4 days, INMI tempo was measured by asking participants to tap to the beat of their INMI with a wrist-worn accelerometer. Participants documented additional details regarding their INMI in a diary. Overall, the tempo of music within INMI was recalled from long-term memory in a highly veridical form, although with a regression to the mean for recalled tempo that parallels previous findings on voluntary musical imagery. A significant positive relationship was found between INMI tempo and subjective arousal, suggesting that INMI interacts with concurrent mood in a similar manner to perceived music. The results suggest several parallels between INMI and voluntary imagery, music perceptual processes, and other types of involuntary memories.

Individual differences in the biomechanical effect of loudness and tempo on upper-limb movements during repetitive piano keystrokes.

Science.gov (United States)

Furuya, Shinichi; Aoki, Tomoko; Nakahara, Hidehiro; Kinoshita, Hiroshi

2012-02-01

The present study addressed the effect of loudness and tempo on kinematics and muscular activities of the upper extremity during repetitive piano keystrokes. Eighteen pianists with professional music education struck two keys simultaneously and repetitively with a combination of four loudness levels and four tempi. The results demonstrated a significant interaction effect of loudness and tempo on peak angular velocity for the shoulder, elbow, wrist and finger joints, mean muscular activity for the corresponding flexors and extensors, and their co-activation level. The interaction effect indicated greater increases with tempo when eliciting louder tones for all joints and muscles except for the elbow velocity showing a greater decrease with tempo. Multiple-regression analysis and K-means clustering further revealed that 18 pianists were categorized into three clusters with different interaction effects on joint kinematics. These clusters were characterized by either an elbow-velocity decrease and a finger-velocity increase, a finger-velocity decrease with increases in shoulder and wrist velocities, or a large elbow-velocity decrease with a shoulder-velocity increase when increasing both loudness and tempo. Furthermore, the muscular load considerably differed across the clusters. These findings provide information to determine muscles with the greatest potential risk of playing-related disorders based on movement characteristics of individual pianists. Copyright © 2011 Elsevier B.V. All rights reserved.

Evolution of man in the light of molecular genetics: a review. Part I. Our evolutionary history and genomics.

Science.gov (United States)

Portin, Petter

2007-07-01

The discovery in the mid 1970s of efficient methods of DNA sequencing and their subsequent development into more and more rapid procedures followed by sequencing the genomes of many species, including man in 2001, revolutionised the whole of biology. Remarkably, new light could be cast on the evolutionary relations of different species, and the tempo and mode of evolution within a given species, notably man, could quantitatively be illuminated including ongoing evolution possibly involving also the size of the brains. This review is a short summary of the results of the molecular genetic investigations of human evolution including the time and place of the formation of our species, our evolutionary relation to the closest living species relatives as well as extinct forms of the genus Homo. The nature and amount of genetic polymorphism in man is also considered with special emphasis on the causes of this variation, and the role of natural selection in human evolution. A consensus about the mosaic nature of our genome and the rather dynamic structure of our ancestral population is gradually emerging. The modern gene pool has most likely been contributed to several different ancestral demes either before or after the emergence of the anatomically modern human phenotype in the extent that even the nature of the evolutionary lineage leading to the anatomically modern man as a distinct biological species is disputable. Regulation of the function of genes, as well as the evolution of brains will be dealt with in the second part of this review.

tempo astorico e spazio mitologico nella riflessione e nella pratica ...

African Journals Online (AJOL)

User

“Tempo astorico” e “spazio mitologico” in Pirandello? Esiste dunque un Pirandello mitologico? È possibile parlare non tanto di miti ma di vera e propria mitologia per uno scrittore come l'Agrigentino che è, senz'ombra di dubbio, il massimo drammaturgo italiano della modernità ed è conosciuto internazionalmente come ...

Análise do tempo de ventilação mecânica e internamento em pacientes submetidos a cirurgia cardíaca

Directory of Open Access Journals (Sweden)

André Luiz Lisboa Cordeiro

2017-04-01

Full Text Available Introdução: Pacientes submetidos à cirurgia cardíaca (CC necessitam de ventilação mecânica invasiva (VMI após o procedimento cirúrgico, sendo que um tempo prolongado de VMI pode levar a um aumento do tempo de permanência na Unidade de Terapia Intensiva (UTI. Objetivo: Verificar se o tempo de VMI interfere no tempo de internação em UTI. Métodos: Foram analisados, prospectivamente, pacientes submetidos à CC e que permaneceram por um tempo inferior a 24 horas na VMI. Foram selecionados 69 pacientes, os quais foram admitidos na UTI e acompanhados até o momento da extubação. Com esse dado encontrou-se o tempo que permaneceram em VMI e, depois, quantos dias permaneceram internados na UTI até o momento da alta da unidade. Resultados: A maior parte dos pacientes submetidos à CC foi do sexo masculino (56,5%; a idade média foi de 55,93±14,29 anos; o tipo de cirurgia mais prevalente foi a revascularização miocárdica (71,0%; o tempo médio de circulação extracorpórea (CEC foi de 65,05±20,06 minutos; o tempo médio de internação na UTI foi de 2,18±1,10 dias; o tempo de VMI foi de 7,32±2,66 horas. Não se verificou significância estatística entre essas duas últimas variáveis com um p=0,43. Conclusão: Pode-se concluir que não houve correlação entre o tempo de ventilação mecânica e tempo de internação em UTI em pacientes que não apresentaram complicações pós-operatórias imediatas e que permaneceram menos de 12 horas sob ventilação mecânica.

[Evolutionary medicine].

Science.gov (United States)

Wjst, M

2013-12-01

Evolutionary medicine allows new insights into long standing medical problems. Are we "really stoneagers on the fast lane"? This insight might have enormous consequences and will allow new answers that could never been provided by traditional anthropology. Only now this is made possible using data from molecular medicine and systems biology. Thereby evolutionary medicine takes a leap from a merely theoretical discipline to practical fields - reproductive, nutritional and preventive medicine, as well as microbiology, immunology and psychiatry. Evolutionary medicine is not another "just so story" but a serious candidate for the medical curriculum providing a universal understanding of health and disease based on our biological origin. © Georg Thieme Verlag KG Stuttgart · New York.

Core principles of evolutionary medicine

Science.gov (United States)

Grunspan, Daniel Z; Nesse, Randolph M; Barnes, M Elizabeth; Brownell, Sara E

2018-01-01

Abstract Background and objectives Evolutionary medicine is a rapidly growing field that uses the principles of evolutionary biology to better understand, prevent and treat disease, and that uses studies of disease to advance basic knowledge in evolutionary biology. Over-arching principles of evolutionary medicine have been described in publications, but our study is the first to systematically elicit core principles from a diverse panel of experts in evolutionary medicine. These principles should be useful to advance recent recommendations made by The Association of American Medical Colleges and the Howard Hughes Medical Institute to make evolutionary thinking a core competency for pre-medical education. Methodology The Delphi method was used to elicit and validate a list of core principles for evolutionary medicine. The study included four surveys administered in sequence to 56 expert panelists. The initial open-ended survey created a list of possible core principles; the three subsequent surveys winnowed the list and assessed the accuracy and importance of each principle. Results Fourteen core principles elicited at least 80% of the panelists to agree or strongly agree that they were important core principles for evolutionary medicine. These principles over-lapped with concepts discussed in other articles discussing key concepts in evolutionary medicine. Conclusions and implications This set of core principles will be helpful for researchers and instructors in evolutionary medicine. We recommend that evolutionary medicine instructors use the list of core principles to construct learning goals. Evolutionary medicine is a young field, so this list of core principles will likely change as the field develops further. PMID:29493660

Proposta de arquitetura de hardware e software para sistemas tempo-real distribuídos

OpenAIRE

Marcelo Gotz

2001-01-01

Um sistema tempo-real caracteriza-se por possuir requisitos temporais para execução de suas atividades, e de acordo com a sua tolerância ao atendimento destes requisitos é classificado em hard-real-time ou soft-real-time. O presente trabalho se propõe a apresentar uma arquitetura de hardware e software para suporte a sistemas tempo-real embarcados de baixo custo com objetivo de aplicação em pesquisas no meio acadêmico e que possa ser usado até em ambientes hard-real-time. A motivação para est...

Applying evolutionary anthropology.

Science.gov (United States)

Gibson, Mhairi A; Lawson, David W

2015-01-01

Evolutionary anthropology provides a powerful theoretical framework for understanding how both current environments and legacies of past selection shape human behavioral diversity. This integrative and pluralistic field, combining ethnographic, demographic, and sociological methods, has provided new insights into the ultimate forces and proximate pathways that guide human adaptation and variation. Here, we present the argument that evolutionary anthropological studies of human behavior also hold great, largely untapped, potential to guide the design, implementation, and evaluation of social and public health policy. Focusing on the key anthropological themes of reproduction, production, and distribution we highlight classic and recent research demonstrating the value of an evolutionary perspective to improving human well-being. The challenge now comes in transforming relevance into action and, for that, evolutionary behavioral anthropologists will need to forge deeper connections with other applied social scientists and policy-makers. We are hopeful that these developments are underway and that, with the current tide of enthusiasm for evidence-based approaches to policy, evolutionary anthropology is well positioned to make a strong contribution. © 2015 Wiley Periodicals, Inc.

Applying Evolutionary Anthropology

Science.gov (United States)

Gibson, Mhairi A; Lawson, David W

2015-01-01

Evolutionary anthropology provides a powerful theoretical framework for understanding how both current environments and legacies of past selection shape human behavioral diversity. This integrative and pluralistic field, combining ethnographic, demographic, and sociological methods, has provided new insights into the ultimate forces and proximate pathways that guide human adaptation and variation. Here, we present the argument that evolutionary anthropological studies of human behavior also hold great, largely untapped, potential to guide the design, implementation, and evaluation of social and public health policy. Focusing on the key anthropological themes of reproduction, production, and distribution we highlight classic and recent research demonstrating the value of an evolutionary perspective to improving human well-being. The challenge now comes in transforming relevance into action and, for that, evolutionary behavioral anthropologists will need to forge deeper connections with other applied social scientists and policy-makers. We are hopeful that these developments are underway and that, with the current tide of enthusiasm for evidence-based approaches to policy, evolutionary anthropology is well positioned to make a strong contribution. PMID:25684561

Long-Term Memory for Music: Infants Remember Tempo and Timbre

Science.gov (United States)

Trainor, Laurel J.; Wu, Luann; Tsang, Christine D.

2004-01-01

We show that infants' long-term memory representations for melodies are not just reduced to the structural features of relative pitches and durations, but contain surface or performance tempo- and timbre-specific information. Using a head turn preference procedure, we found that after a one week exposure to an old English folk song, infants…

Effects of music tempo on performance, psychological, and physiological variables during 20 km cycling in well-trained cyclists.

Science.gov (United States)

2013-10-01

Few studies have investigated the effects of music on trained athletes during high intensity endurance tasks. Therefore, this study investigated the effects of different music tempi on performance, psychological, and physiological responses of well-trained cyclists to time trial cycling. 10 male road cyclists (M age = 35 yr., SD = 7), with a minimum of three years racing experience, performed four 20-km time trials on a Computrainer Pro 3D indoor cycle trainer over a period of four weeks. The time-trials were spaced one week apart. The music conditions for each trial were randomised between fast-tempo (140 bpm), medium-tempo (120 bpm), slow-tempo (100 bpm), and no music. Performance (completion time, power output, average speed and cadence), physiological (heart rate, oxygen consumption, breathing frequency and respiratory exchange ratio), psychophysical (RPE), and psychological (mood states) data were collected for each trial. Results indicated no significant changes in performance, physiological, or psychophysical variables. Total mood disturbance and tension increased significantly in the fast-tempo trial when compared with medium and no-music conditions.

Intra- and intersubject comparison of cochlear implant systems using the Esprit and the Tempo+ behind-the-ear speech processor.

Science.gov (United States)

Kompis, Martin; Jenk, Martin; Vischer, Mattheus W; Seifert, Eberhard; Häusler, Rudolf

2002-12-01

A patient with bilateral profound deafness was implanted with a Nucleus CI24M cochlear implant (CI) and used an Esprit behind-the-ear (BTE) speech processor. Thirteen months later, the implant had to be removed because of a cholesteatoma. As the same electrode could not be reinserted, a Medel combi40s CI was implanted in the same ear, and the patient used a Tempo+ BTE processor. After 1 year of use of the Combi40s/Tempo+ system, speech recognition was better and was rated better subjectively than with the CI24M/Esprit system. Speech recognition and subjective ratings were also assessed for two matched groups of nine CI users each, using either an Esprit or a Tempo+ processor. On average, speech recognition scores were higher for the group of Tempo+ users, but the difference was not statistically significant. Users of the Esprit processors rated their device higher in terms of cosmetic appearance and comfort of wearing.

Evolutionary Expectations

DEFF Research Database (Denmark)

Nash, Ulrik William

2014-01-01

, they are correlated among people who share environments because these individuals satisfice within their cognitive bounds by using cues in order of validity, as opposed to using cues arbitrarily. Any difference in expectations thereby arise from differences in cognitive ability, because two individuals with identical...... cognitive bounds will perceive business opportunities identically. In addition, because cues provide information about latent causal structures of the environment, changes in causality must be accompanied by changes in cognitive representations if adaptation is to be maintained. The concept of evolutionary......The concept of evolutionary expectations descends from cue learning psychology, synthesizing ideas on rational expectations with ideas on bounded rationality, to provide support for these ideas simultaneously. Evolutionary expectations are rational, but within cognitive bounds. Moreover...

Evolutionary Awareness

Directory of Open Access Journals (Sweden)

Gregory Gorelik

2014-10-01

Full Text Available In this article, we advance the concept of “evolutionary awareness,” a metacognitive framework that examines human thought and emotion from a naturalistic, evolutionary perspective. We begin by discussing the evolution and current functioning of the moral foundations on which our framework rests. Next, we discuss the possible applications of such an evolutionarily-informed ethical framework to several domains of human behavior, namely: sexual maturation, mate attraction, intrasexual competition, culture, and the separation between various academic disciplines. Finally, we discuss ways in which an evolutionary awareness can inform our cross-generational activities—which we refer to as “intergenerational extended phenotypes”—by helping us to construct a better future for ourselves, for other sentient beings, and for our environment.

EVOLUTIONARY FOUNDATIONS FOR MOLECULAR MEDICINE

Science.gov (United States)

Nesse, Randolph M.; Ganten, Detlev; Gregory, T. Ryan; Omenn, Gilbert S.

2015-01-01

Evolution has long provided a foundation for population genetics, but many major advances in evolutionary biology from the 20th century are only now being applied in molecular medicine. They include the distinction between proximate and evolutionary explanations, kin selection, evolutionary models for cooperation, and new strategies for tracing phylogenies and identifying signals of selection. Recent advances in genomics are further transforming evolutionary biology and creating yet more opportunities for progress at the interface of evolution with genetics, medicine, and public health. This article reviews 15 evolutionary principles and their applications in molecular medicine in hopes that readers will use them and others to speed the development of evolutionary molecular medicine. PMID:22544168

Attractive evolutionary equilibria

NARCIS (Netherlands)

Joosten, Reinoud A.M.G.; Roorda, Berend

2011-01-01

We present attractiveness, a refinement criterion for evolutionary equilibria. Equilibria surviving this criterion are robust to small perturbations of the underlying payoff system or the dynamics at hand. Furthermore, certain attractive equilibria are equivalent to others for certain evolutionary

Considerações sobre a idéia de tempo em Sto. Agostinho, Hume e Kant

Directory of Open Access Journals (Sweden)

Marcelo Carbone Carneiro

2004-08-01

Full Text Available Discute-se sobre o tempo buscando entendê-lo a partir dos referenciais que o tomam como elaboração subjetiva, ou seja, como não possuindo qualquer realidade fora do sujeito. Entende-se que, na história da Filosofia, esta reflexão inicia-se com a filosofia de Sto. Agostinho e tem seu ápice no pensamento moderno, sobretudo em Hume e Kant. O tempo seria uma construção ou elaboração do espírito, sem existência fora dele (Sto. Agostinho ou uma apreensão empírica regular de relações causais de antes e depois (Hume ou uma intuição pura do espírito (Kant. Pretende-se, com esta análise, evidenciar uma forma clássica de conceber o tempo como elaboração realizada pelo sujeito (subjetiva.

Open Issues in Evolutionary Robotics.

Science.gov (United States)

Silva, Fernando; Duarte, Miguel; Correia, Luís; Oliveira, Sancho Moura; Christensen, Anders Lyhne

2016-01-01

One of the long-term goals in evolutionary robotics is to be able to automatically synthesize controllers for real autonomous robots based only on a task specification. While a number of studies have shown the applicability of evolutionary robotics techniques for the synthesis of behavioral control, researchers have consistently been faced with a number of issues preventing the widespread adoption of evolutionary robotics for engineering purposes. In this article, we review and discuss the open issues in evolutionary robotics. First, we analyze the benefits and challenges of simulation-based evolution and subsequent deployment of controllers versus evolution on real robotic hardware. Second, we discuss specific evolutionary computation issues that have plagued evolutionary robotics: (1) the bootstrap problem, (2) deception, and (3) the role of genomic encoding and genotype-phenotype mapping in the evolution of controllers for complex tasks. Finally, we address the absence of standard research practices in the field. We also discuss promising avenues of research. Our underlying motivation is the reduction of the current gap between evolutionary robotics and mainstream robotics, and the establishment of evolutionary robotics as a canonical approach for the engineering of autonomous robots.

Adopting a music-to-heart rate alignment strategy to measure the impact of music and its tempo on human heart rate

OpenAIRE

Van Dyck, Edith; Six, Joren; Soyer, Esin Nisa; Denys, Marlies; Bardijn, Ilka; Leman, Marc

2017-01-01

Music is frequently used as a means of relaxation. Conversely, it is used as a means of arousal in sports and exercise contexts. Previous research suggests that tempo is one of the most significant determinants of music-related arousal and relaxation effects. Here we investigate the specific effect of music tempo, but also more generally, the influence of music on human heart rate. We took the pulses of 32 participants in silence, and then we played them non-vocal, ambient music at a tempo co...

Tempo e patrimônio Temporality and patrimony

Directory of Open Access Journals (Sweden)

François Hartog

2006-12-01

Full Text Available O artigo discute a redefinição da "memória" e do "patrimônio" dentro do novo "regime de historicidade" que o Ocidente vive após a Queda do Muro de Berlim (1989. Estas palavras-chave são tratadas como indícios, sintomas, de nossa relação com o tempo, como testemunhas da "crise" da ordem presente do tempo. O problema abordado: um novo regime de historicidade, centrado sobre o presente, estaria se formulando? Para o autor, ocorreu um crescimento rápido da categoria do presente e se impôs a evidência de um presente onipresente, que ele nomeia "presentismo", onde se vive entre a amnésia e a vontade de nada esquecer.This article discusses the redefinition of "memory" and "patrimony" within the new "regime of historicity" set in motion in the West after the fall of the Berlin Wall (1989. These keywords are treated as indicators or symptoms of our relation with time, as witnesses of the "crises" of the present order of time. The question that is approached is the following: is a new regime of historicity, one based on the present, taking shape? In the author's view, the category of present has grown rather fast and imposed an omnipotent present, which he names "presentism". This condition causes one to be torn between amnesia and the desire not to forget.

Effects of Style, Tempo, and Performing Medium on Children's Music Preference.

Science.gov (United States)

LeBlanc, Albert

1981-01-01

Fifth-graders listened to a tape incorporating fast and slow vocal and instrumental excerpts within the generic styles of rock/pop, country, older jazz, newer jazz, art music, and band music. A preference hierarchy emerged favoring the popular styles. Across pooled styles, faster tempos and instrumentals were slightly preferred. (Author/SJL)

Gestão do tempo como apoio ao planejamento estratégico pessoal Time management and support to personal strategic planning

Directory of Open Access Journals (Sweden)

Cristiano Descovi Schimith

2011-08-01

Full Text Available Este estudo parte do pressuposto de que a gestão do tempo pode auxiliar o planejamento estratégico pessoal, sistematizando sua implantação. Desta forma, o objetivo do trabalho consiste em propor um modelo de gestão do tempo que contribua com a implantação do planejamento estratégico pessoal. Para atingi-lo, o estudo tem seus fundamentos teóricos no Planejamento Estratégico, no Planejamento Estratégico Pessoal e na Gestão do Tempo. A análise da literatura permitiu identificar elementos essenciais para a composição do modelo proposto. Os resultados obtidos revelam um Modelo de Gestão do Tempo, lógico e sequencial, que envolve fatores técnicos e comportamentais, composto por três fases: auditoria do tempo (situação real, alavancagem do tempo (situação ideal e enquadramento do tempo (planejamento semanal, planejamento diário e priorização. This study assumes that time management can support the personal strategic planning, streamlining its implementation. So the objective of this study is to propose a model of time management that contributes to the implementation of the strategic planning personal. To achieve it, the study has its theoretical foundations in Strategic Planning, Strategic Planning Personal and Time Management. The literature review identified key elements in the composition of the proposed model. The results reveal a Model of Time Management, logical and sequential, which involves technical and behavioral factors. The model consists of three phases: audit of time (real situation, leverage the time (ideal situation and the time frame (weekly planning, daily planning and prioritizing.

UM ESTUDO SOBRE O TEMPO-PADRÃO NO PROCESSO PRODUTIVO DE RECAPAGEM DE PNEUS EM UMA CONCESSIONÁRIA DE VEÍCULOS

Directory of Open Access Journals (Sweden)

Andreas Dittmar Weise

2013-01-01

Full Text Available Em um contexto de um mercado cada vez mais competitivo, as empresas necessitam manter-se em constante busca por aperfeiçoamento em seus processos. Para isso, a administração eficaz dos seus processos produtivos e das operações desenvolvidas traz consigo elementos voltados para o alcance dos objetivos estratégicos, podendo ocasionar sucessivas reduções de uso desnecessário dos recursos, de tempo e, consequentemente, de capital, o que poderá gerar mais ganhos financeiros e menor desperdício. Assim, este artigo tem como objetivo analisar o processo produtivo da recapagem de pneus em uma concessionária de veículos através do estudo do tempo-padrão das operações. O estudo desenvolveu-se por meio de um estudo de caso, com abordagens qualitativa e quantitativa, do tipo descritiva. Primeiramente, através de observação in loco, analisaram-se, durante o processo de recapagem de pneus, o tempo normal e o tempo-padrão das atividades desempenhadas e, posteriormente, todas as etapas foram devidamente cronometradas, mediante doze repetições, para, então, se chegar ao cálculo do tempo médio de cada etapa do processo de recapagem. Como resultados, destaca-se que, em grande parte das etapas do processo, o tempo médio e o tempo-padrão identificados são semelhantes, não apresentando discrepância significativa entre os valores encontrados. No entanto, o problema referente à rotatividade de colaboradores no setor é uma questão que precisa ser analisada com mais atenção por parte dos gestores da empresa. Palavras-chave: Gestão da produção. Gerenciamento de processos. Planejamento de recursos.

Influência do tempo de aclimatação na resposta do cajueiro à salinidade

OpenAIRE

Brilhante, Jean C. A.; Silveira, Joaquim A. G.; Rocha, Iza M. A.; Morais, Déborah L. de; Viégas, Ricardo A.

2007-01-01

A resposta das plantas à salinidade depende de fatores fisiológicos, bioquímicos e genéticos. Com este trabalho, objetivou-se estudar o impacto do tempo de aclimatação à solução nutritiva sobre a resposta do cajueiro à salinidade. Plantas de Anarcadium occidentale L., CCP06, cultivadas em vermiculita durante 28 dias, foram transferidas para solução nutritiva de Hoagland com 1/10 de sua força iônica, onde permaneceram por 1 e 7 dias. Ao final dos dois tempos, a solução nutritiva foi suplementa...

Practical Aerobic Oxidations of Alcohols and Amines with Homogeneous Cu/TEMPO and Related Catalyst Systems

Science.gov (United States)

Ryland, Bradford L.; Stahl, Shannon S.

2014-01-01

Alcohol and amine oxidations are common reactions in laboratory and industrial synthesis of organic molecules. Aerobic oxidation methods have long been sought for these transformations, but few practical methods exist that offer advantages over traditional oxidation methods. Recently developed homogeneous Cu/TEMPO (TEMPO = 2,2,6,6-tetramethylpiperidinyl-N-oxyl) and related catalyst systems appear to fill this void. The reactions exhibit high levels of chemoselectivity and broad functional-group tolerance, and they often operate efficiently at room temperature with ambient air as the oxidant. These advances, together with their historical context and recent applications, are highlighted in this minireview. PMID:25044821

Romancização ou serialização: ou diferentes formas de tempo

Directory of Open Access Journals (Sweden)

Peter Hitchcock

2015-11-01

Full Text Available Este artigo explora a noção bakhtiniana de romancização no que se refere à sua teoria de tempo e serialização. Bakhtin, para quem o romance é histórico, mas sem história, remonta à Grécia antiga para traçar a história do romance. Sem dar a ele uma identidade fixa, compreende-o em termos de tendências e crises. A romancização, para Bakhtin, é um meio de tornar a história literária acessível a uma análise mais dialógica da forma e um modo discursivo para avaliar ideologias criticamente. Ele enfatiza a habilidade desestabilizadora do romance, sua descentralização do discurso e sua acomodação de vozes não oficiais e estrangeiras. Seu sugestivo relato histórico do desenvolvimento do romance nos permite estender seu pensamento e esboçar a romancização mais como uma condição futura do que uma lei genérica. Bakhtin oferece uma versão problemática de modernidade, na qual o romance ativa a influência do tempo sobre o presente; no entanto, por causa da propensão à crise da modernidade, o tempo é suspenso. O artigo também examina um cronotopo do romance sobre o qual Bakhtin tem pouco a dizer: o tempo/espaço da nação. Benedict Anderson e Etienne Balibar, cujos interesses incluem temas relacionados ao comparatismo, ao multiculturalismo e ao pós-colonialismo, questionam a ideia de nação por meio de análises em que o gênero romanesco é privilegiado.

Experimental test of an eco-evolutionary dynamic feedback loop between evolution and population density in the green peach aphid.

Science.gov (United States)

Turcotte, Martin M; Reznick, David N; Daniel Hare, J

2013-05-01

An eco-evolutionary feedback loop is defined as the reciprocal impacts of ecology on evolutionary dynamics and evolution on ecological dynamics on contemporary timescales. We experimentally tested for an eco-evolutionary feedback loop in the green peach aphid, Myzus persicae, by manipulating initial densities and evolution. We found strong evidence that initial aphid density alters the rate and direction of evolution, as measured by changes in genotype frequencies through time. We also found that evolution of aphids within only 16 days, or approximately three generations, alters the rate of population growth and predicts density compared to nonevolving controls. The impact of evolution on population dynamics also depended on density. In one evolution treatment, evolution accelerated population growth by up to 10.3% at high initial density or reduced it by up to 6.4% at low initial density. The impact of evolution on population growth was as strong as or stronger than that caused by a threefold change in intraspecific density. We found that, taken together, ecological condition, here intraspecific density, alters evolutionary dynamics, which in turn alter concurrent population growth rate (ecological dynamics) in an eco-evolutionary feedback loop. Our results suggest that ignoring evolution in studies predicting population dynamics might lead us to over- or underestimate population density and that we cannot predict the evolutionary outcome within aphid populations without considering population size.

O regime de dedicação exclusiva e a gestão do tempo: estudo de caso com docentes universitários.

Directory of Open Access Journals (Sweden)

Leonardo de Brito Quevedo

2013-12-01

Full Text Available Esta pesquisa propôs investigar o comportamento dos docentes atuantes sob regime dededicação exclusiva na UNIPAMPA, frente à gestão do tempo de trabalho e tempo livre. Oestudo teve caráter exploratório e descritivo, pois procurou compreender o comportamento deum grupo particular, configurando-se, portanto, como um estudo de caso. Escolheu-se comotécnica de coleta de dados a entrevista semiestruturada. Doze docentes foram entrevistados.Conclui-se que todos os docentes mantêm uma gestão do tempo de trabalho e do tempo livre,evidenciando que a atividade docente interfere na vida pessoal dos mesmos, principalmentena quantidade de tarefas do trabalho levadas para casa.

PERFIL SENSORIAL DE CULTIVARES DE FEIJÃO SOB DIFERENTES TEMPOS DE COZIMENTO

Directory of Open Access Journals (Sweden)

Viviani Ruffo de OLIVEIRA

2013-04-01

Full Text Available O objetivo deste trabalho foi determinar o tempo necessário de cozimento de cultivares de feijão de grãos preto e carioca, em panela de pressão doméstica, para a identificação de cultivares de melhor perfil sensorial para o consumo. Para tanto, utilizaram-se grãos de quatro cultivares de feijão: BRS Expedito, BRS Campeiro, Pérola e Carioca e o cozimento foi realizado em panela de pressão doméstica por 15, 20, 25 e 30 minutos. A avaliação do perfil sensorial foi efetuada em três etapas: seleção, treinamento para a Análise Descritiva Quantitativa (ADQ e ADQ propriamente dita, com sete avaliadores treinados. Os avaliadores reconheceram diferenças para as cultivares de feijão quanto à uniformidade da cor do grão, cor do caldo, à viscosidade, à dureza e a granulosidade. A ruptura no tegumento dos grãos foi maior à medida que se aumentou o tempo de cozimento. A dureza e a granulosidade apresentaram maiores intensidades conforme aumentou o tempo de cozimento dos grãos de feijão. A utilização de 20 a 25 minutos de cozimento em panela de pressão doméstica possibilita a identificação de cultivares de feijão de grãos preto e carioca com melhor perfil sensorial para o consumo, mantendo a integridade dos grãos cozidos.

First comparative study of primate morphological and molecular evolutionary rates including muscle data: implications for the tempo and mode of primate and human evolution

Science.gov (United States)

Diogo, Rui; Peng, Zuogang; Wood, Bernard

2013-01-01

Here we provide the first report about the rates of muscle evolution derived from Bayesian and parsimony cladistic analyses of primate higher-level phylogeny, and compare these rates with published rates of molecular evolution. It is commonly accepted that there is a ‘general molecular slow-down of hominoids’, but interestingly the rates of muscle evolution in the nodes leading and within the hominoid clade are higher than those in the vast majority of other primate clades. The rate of muscle evolution at the node leading to Homo (1.77) is higher than that at the nodes leading to Pan (0.89) and particularly to Gorilla (0.28). Notably, the rates of muscle evolution at the major euarchontan and primate nodes are different, but within each major primate clade (Strepsirrhini, Platyrrhini, Cercopithecidae and Hominoidea) the rates at the various nodes, and particularly at the nodes leading to the higher groups (i.e. including more than one genera), are strikingly similar. We explore the implications of these new data for the tempo and mode of primate and human evolution. PMID:23320764

The Effect of Montessori Method on Cognitive Tempo of Kindergarten Children

Science.gov (United States)

Kayili, Gökhan

2018-01-01

This study was undertaken to discover the effect of the Montessori Method on the cognitive tempo of 4-5-year-old children. Using an experimental pre-test-post-test paired control group design, the study sample included 60 children attending Ihsan Dogramaci Applied Nursery School (affiliated to Selcuk University, Department of Health Sciences) in…

Prenatal influences on size, velocity and tempo of infant growth: findings from three contemporary cohorts.

Directory of Open Access Journals (Sweden)

Costanza Pizzi

Full Text Available Studying prenatal influences of early life growth is relevant to life-course epidemiology as some of its features have been linked to the onset of later diseases.We studied the association between prenatal maternal characteristics (height, age, parity, education, pre-pregnancy body mass index (BMI, smoking, gestational diabetes and hypertension and offspring weight trajectories in infancy using SuperImposition by Translation And Rotation (SITAR models, which parameterize growth in terms of three biologically interpretable parameters: size, velocity and tempo. We used data from three contemporary cohorts based in Portugal (GXXI, n=738, Italy (NINFEA, n=2,925, and Chile (GOCS, n=959.Estimates were generally consistent across the cohorts for maternal height, age, parity and pre-pregnancy overweight/obesity. Some exposures only affected one growth parameter (e.g. maternal height (per cm: 0.4% increase in size (95% confidence interval (CI:0.3; 0.5, others were either found to affect size and velocity (e.g. pre-pregnancy underweight vs normal weight: smaller size (-4.9%, 95% CI:-6.5; -3.3, greater velocity (5.9%, 95% CI:1.9;10.0, or to additionally influence tempo (e.g. pre-pregnancy overweight/obesity vs normal weight: increased size (7.9%, 95% CI:4.9;10.8, delayed tempo (0.26 months, 95% CI:0.11;0.41, decreased velocity (-4.9%, 95% CI: -10.8;0.9.By disentangling the growth parameters of size, velocity and tempo, we found that prenatal maternal characteristics, especially maternal smoking, pre-pregnancy overweight and underweight, parity and gestational hypertension, are associated with different aspects of infant weight growth. These results may offer insights into the mechanisms governing infant growth.

Experimentação do tempo e estilo de vida em contexto de trabalho imaterial

Directory of Open Access Journals (Sweden)

Carmem Ligia Iochins Grisci

Full Text Available Este artigo buscou responder, em contexto de trabalho imaterial, que estilo de vida decorre do uso do tempo permeado pelas tecnologias da informação e comunicação. O estudo qualitativo contou com a participação de 18 docentes horistas de instituições de ensino superior privadas. A coleta de dados se deu por meio de entrevista individual semiestruturada, com foco no uso das tecnologias da informação e comunicação e no exercício do trabalho imaterial, considerando o tempo de trabalho e de não trabalho. A análise de conteúdo partiu dos dados coletados. Os resultados, em consonância com a literatura ( em especial, Bauman (2008b, Deleuze (1998, Giddens (2002, Gorz (2005 e Lazzarato e Negri (2001 (apontaram que, em contexto de trabalho imaterial, o estilo de vida é instrumentalizado pelo modo de trabalhar e pelo uso das tecnologias de informação e comunicação. Ele se configura como uma imposição aos sujeitos que o toma na perspectiva de uma estratégia existencial consumista. Mesmo contratado por tempo fracionado em horas, o trabalho dos docentes horistas exige-lhes disponibilidade e mobilização total para o desempenho das atividades laborais, requerendo dedicação em tempo integral. Os estilos de trabalho produzem estilo de vida e sugerem que a vida está sendo convertida em trabalho nos dias de hoje, tanto pela intensificação do trabalho, como pelo prolongamento da jornada.

TEMPO functionalized C60 fullerene deposited on gold surface for catalytic oxidation of selected alcohols

International Nuclear Information System (INIS)

Piotrowski, Piotr; Pawłowska, Joanna; Sadło, Jarosław Grzegorz; Bilewicz, Renata; Kaim, Andrzej

2017-01-01

C 60 TEMPO 10 catalytic system linked to a microspherical gold support through a covalent S-Au bond was developed. The C 60 TEMPO 10 @Au composite catalyst had a particle size of 0.5–0.8 μm and was covered with the fullerenes derivative of 2.3 nm diameter bearing ten nitroxyl groups; the organic film showed up to 50 nm thickness. The catalytic composite allowed for the oxidation under mild conditions of various primary and secondary alcohols to the corresponding aldehyde and ketone analogues with efficiencies as high as 79–98%, thus giving values typical for homogeneous catalysis, while retaining at the same time all the advantages of heterogeneous catalysis, e.g., easy separation by filtration from the reaction mixture. The catalytic activity of the resulting system was studied by means of high pressure liquid chromatography. A redox mechanism was proposed for the process. In the catalytic cycle of the oxidation process, the TEMPO moiety was continuously regenerated in situ with an applied primary oxidant, for example, O 2 /Fe 3+ system. The new intermediate composite components and the final catalyst were characterized by various spectroscopic methods and thermogravimetry.

ANÁLISE DE DESEMPENHO EM REDES IEEE 802.3 APLICADO PARA SISTEMA DE TEMPO REAL

Directory of Open Access Journals (Sweden)

Ricardo Alexsandro de Medeiros Valentim

2011-06-01

Full Text Available A tecnologia Ethernet domina o mercado de rede local de computadores. No entanto, não foi estabelecida como uma tecnologia para automação industrial, onde o determinismo procura os requisitos com um desempenho de tempo real. Muitas soluções têm sido propostas para resolver o problema do determinismo não, que se baseiam principalmente no TDMA (acesso múltiplo por divisão de tempo, passagem de token e mestre-escravo. É neste contexto que este trabalho é realizado, através de medidas de desempenho em redes de comunicação que utilizam o padrão IEEE 802.3, observando o comportamento destas redes, quando submetidos a diferentes cenários de sobrecarga. Para isso, as variações foram aprovadas em ambiente de teste, que será baseado em Shared Ethernet (Hub, Ethernet e Ethernet Switch com prioridade (IEEE 802.1Q. Desta forma, é possível indicar quais os dispositivos analisados pelos testes de desempenho demonstrado um comportamento mais adequado para suportar as aplicações com requisitos de tempo real.

A teia, a tela e o tempo: internet e história do tempo presente

Directory of Open Access Journals (Sweden)

Pedro Eurico Rodrigues

2014-09-01

Full Text Available O enfoque deste artigo será uma apresentação da pesquisa em história e Internet, pensando esta como um documento dentro dos estudos da História da Cultura Escrita e da Leitura. Ao propiciar novas formas de ler e escrever na contemporaneidade, a Internet perpassa por várias modalidades tais como os comunicadores instantâneos (MIRC e MSN, as redes sociais (Orkut, Facebook, notícias, vídeos entre outros. Com destaque a novos mecanismos de sociabilidade que funcionam como mediadores para interação entre grupos que utilizam as redes sociais. Os documentos são abordados na perspectiva da História do Tempo Presente, que possibilita pensarmos um passado-presente, em que os recuos e aproximações com as fontes são possibilitados pelas escolhas do historiador que problematiza este Presente Palavras-chave: História; Escrita; Leitura; Redes de Relações Sociais.

Selective Exposure to and Acquisition of Information from Educational Television Programs as a Function of Appeal and Tempo of Background Music.

Science.gov (United States)

Wakshlag, Jacob J.; And Others

1982-01-01

The effect of educational television background music on selective exposure and information acquisition was studied. Background music of slow tempo, regardless of its appeal, had negligible effects on attention and information acquisition. Rhythmic, fast-tempo background music, especially when appealing, significantly reduced visual attention to…

Evolutionary Demography

DEFF Research Database (Denmark)

Levitis, Daniel

2015-01-01

of biological and cultural evolution. Demographic variation within and among human populations is influenced by our biology, and therefore by natural selection and our evolutionary background. Demographic methods are necessary for studying populations of other species, and for quantifying evolutionary fitness......Demography is the quantitative study of population processes, while evolution is a population process that influences all aspects of biological organisms, including their demography. Demographic traits common to all human populations are the products of biological evolution or the interaction...

Proteomics in evolutionary ecology.

Science.gov (United States)

Baer, B; Millar, A H

2016-03-01

Evolutionary ecologists are traditionally gene-focused, as genes propagate phenotypic traits across generations and mutations and recombination in the DNA generate genetic diversity required for evolutionary processes. As a consequence, the inheritance of changed DNA provides a molecular explanation for the functional changes associated with natural selection. A direct focus on proteins on the other hand, the actual molecular agents responsible for the expression of a phenotypic trait, receives far less interest from ecologists and evolutionary biologists. This is partially due to the central dogma of molecular biology that appears to define proteins as the 'dead-end of molecular information flow' as well as technical limitations in identifying and studying proteins and their diversity in the field and in many of the more exotic genera often favored in ecological studies. Here we provide an overview of a newly forming field of research that we refer to as 'Evolutionary Proteomics'. We point out that the origins of cellular function are related to the properties of polypeptide and RNA and their interactions with the environment, rather than DNA descent, and that the critical role of horizontal gene transfer in evolution is more about coopting new proteins to impact cellular processes than it is about modifying gene function. Furthermore, post-transcriptional and post-translational processes generate a remarkable diversity of mature proteins from a single gene, and the properties of these mature proteins can also influence inheritance through genetic and perhaps epigenetic mechanisms. The influence of post-transcriptional diversification on evolutionary processes could provide a novel mechanistic underpinning for elements of rapid, directed evolutionary changes and adaptations as observed for a variety of evolutionary processes. Modern state-of the art technologies based on mass spectrometry are now available to identify and quantify peptides, proteins, protein

Nos tempos de Asclépio: a suposta engenharia genética de Platão

Directory of Open Access Journals (Sweden)

Sussumo Matsui

2016-01-01

Full Text Available A descrição do papel da medicina no Livro III da República pode facilmente deixar o leitor constrangido. O trecho defende que a medicina deveria se espelhar nas práticas do tempo de Asclépio. Neste tempo, a medicina tinha um papel político de não prolongar a vida dos cidadãos tomados pela doença e nem deixá-los procriar. Frente a estas declarações, surgiram várias interpretações que vão desde o totalitarismo de Popper até a ironia de Strauss. Para uma melhor compreensão do texto, seria necessária a interlocução com a medicina hipocrática e com as práticas médicas do tempo dos séculos V e IV aEN. Contudo, a passagem em questão não se reduz ao contexto histórico, mas apresenta uma crítica válida ainda na atualidade.

Mitochondria-Targeted Antioxidant Mito-Tempo Protects Against Aldosterone-Induced Renal Injury In Vivo

Directory of Open Access Journals (Sweden)

Wei Ding

2017-11-01

Full Text Available Background/Aims: Growing evidence suggests mitochondrial dysfunction (MtD and the Nlrp3 inflammasome play critical roles in chronic kidney disease (CKD progression. We previously reported that Aldosterone (Aldo-induced renal injury in vitro is directly caused by mitochondrial reactive oxygen species (mtROS-mediated activation of the Nlrp3 inflammasome. Here we aimed to determine whether a mitochondria-targeted antioxidant (Mito-Tempo could prevent Aldo-induced kidney damage in vivo. Methods: C57BL/6J mice were treated with Aldo and/or Mito-Tempo (or ethanol as a control for 4 weeks. Renal injury was evaluated by Periodic Acid-Schiff reagent or Masson’s trichrome staining and electron microscopy. ROS were measured by DCFDA fluorescence and ELISA. MtD was determined by real-time PCR and electron microscopy. Activation of the Nlrp3 inflammasome and endoplasmic reticulum stress (ERS was detected via western blot. Results: Compared with control mice, Aldo-infused mice showed impaired renal function, increased mtROS production and MtD, Nlrp3 inflammasome activation, and elevated ERS. We showed administration of Mito-Tempo significantly improved renal function and MtD, and reduced Nlrp3 inflammasome activation and ERS in vivo. Conclusion: Mitochondria-targeted antioxidants may attenuate Aldo-infused renal injury by inhibiting MtD, the Nlrp3 inflammasome, and ERS in vivo. Therefore, targeting mtROS might be an effective strategy for preventing CKD.

Presente: o tempo do jornalismo e seus desdobramentos

OpenAIRE

Dalmonte, Edson

2010-01-01

p. 328-344 Discute a noção de temporalidade no campo do jornalismo. Partindo do princípio de que a atualidade é a base da narrativa jornalística, reflete acerca dos dispositivos empregados para dar densidade ao presente: o passado, como elemento da memória e o futuro, como projeção. Dessa forma, procura entender os modos a partir dos quais o jornalismo estabelece estratégias capazes de criar o sentido de "presentificação", simulando a ideia de atualidade, o que coloca num mesmo plano tempo...

Extinction Events Can Accelerate Evolution

DEFF Research Database (Denmark)

Lehman, Joel; Miikkulainen, Risto

2015-01-01

Extinction events impact the trajectory of biological evolution significantly. They are often viewed as upheavals to the evolutionary process. In contrast, this paper supports the hypothesis that although they are unpredictably destructive, extinction events may in the long term accelerate...... evolution by increasing evolvability. In particular, if extinction events extinguish indiscriminately many ways of life, indirectly they may select for the ability to expand rapidly through vacated niches. Lineages with such an ability are more likely to persist through multiple extinctions. Lending...... computational support for this hypothesis, this paper shows how increased evolvability will result from simulated extinction events in two computational models of evolved behavior. The conclusion is that although they are destructive in the short term, extinction events may make evolution more prolific...

Gene family size conservation is a good indicator of evolutionary rates.

Science.gov (United States)

Chen, Feng-Chi; Chen, Chiuan-Jung; Li, Wen-Hsiung; Chuang, Trees-Juen

2010-08-01

The evolution of duplicate genes has been a topic of broad interest. Here, we propose that the conservation of gene family size is a good indicator of the rate of sequence evolution and some other biological properties. By comparing the human-chimpanzee-macaque orthologous gene families with and without family size conservation, we demonstrate that genes with family size conservation evolve more slowly than those without family size conservation. Our results further demonstrate that both family expansion and contraction events may accelerate gene evolution, resulting in elevated evolutionary rates in the genes without family size conservation. In addition, we show that the duplicate genes with family size conservation evolve significantly more slowly than those without family size conservation. Interestingly, the median evolutionary rate of singletons falls in between those of the above two types of duplicate gene families. Our results thus suggest that the controversy on whether duplicate genes evolve more slowly than singletons can be resolved when family size conservation is taken into consideration. Furthermore, we also observe that duplicate genes with family size conservation have the highest level of gene expression/expression breadth, the highest proportion of essential genes, and the lowest gene compactness, followed by singletons and then by duplicate genes without family size conservation. Such a trend accords well with our observations of evolutionary rates. Our results thus point to the importance of family size conservation in the evolution of duplicate genes.

Dissociation Behavior of a TEMPO-Active Ester Cross-Linker for Peptide Structure Analysis by Free Radical Initiated Peptide Sequencing (FRIPS) in Negative ESI-MS.

Science.gov (United States)

Hage, Christoph; Ihling, Christian H; Götze, Michael; Schäfer, Mathias; Sinz, Andrea

2017-01-01

We have synthesized a homobifunctional amine-reactive cross-linking reagent, containing a TEMPO (2,2,6,6-tetramethylpiperidine-1-oxy) and a benzyl group (Bz), termed TEMPO-Bz-linker, to derive three-dimensional structural information of proteins. The aim for designing this novel cross-linker was to facilitate the mass spectrometric analysis of cross-linked products by free radical initiated peptide sequencing (FRIPS). In an initial study, we had investigated the fragmentation behavior of TEMPO-Bz-derivatized peptides upon collision activation in (+)-electrospray ionization collision-induced dissociation tandem mass spectrometry (ESI-CID-MS/MS) experiments. In addition to the homolytic NO-C bond cleavage FRIPS pathway delivering the desired odd-electron product ions, an alternative heterolytic NO-C bond cleavage, resulting in even-electron product ions mechanism was found to be relevant. The latter fragmentation route clearly depends on the protonation of the TEMPO-Bz-moiety itself, which motivated us to conduct (-)-ESI-MS, CID-MS/MS, and MS 3 experiments of TEMPO-Bz-cross-linked peptides to further clarify the fragmentation behavior of TEMPO-Bz-peptide molecular ions. We show that the TEMPO-Bz-linker is highly beneficial for conducting FRIPS in negative ionization mode as the desired homolytic cleavage of the NO-C bond is the major fragmentation pathway. Based on characteristic fragments, the isomeric amino acids leucine and isoleucine could be discriminated. Interestingly, we observed pronounced amino acid side chain losses in cross-linked peptides if the cross-linked peptides contain a high number of acidic amino acids. Graphical Abstract ᅟ.

A backtracking evolutionary algorithm for power systems

Directory of Open Access Journals (Sweden)

Chiou Ji-Pyng

2017-01-01

Full Text Available This paper presents a backtracking variable scaling hybrid differential evolution, called backtracking VSHDE, for solving the optimal network reconfiguration problems for power loss reduction in distribution systems. The concepts of the backtracking, variable scaling factor, migrating, accelerated, and boundary control mechanism are embedded in the original differential evolution (DE to form the backtracking VSHDE. The concepts of the backtracking and boundary control mechanism can increase the population diversity. And, according to the convergence property of the population, the scaling factor is adjusted based on the 1/5 success rule of the evolution strategies (ESs. A larger population size must be used in the evolutionary algorithms (EAs to maintain the population diversity. To overcome this drawback, two operations, acceleration operation and migrating operation, are embedded into the proposed method. The feeder reconfiguration of distribution systems is modelled as an optimization problem which aims at achieving the minimum loss subject to voltage and current constraints. So, the proper system topology that reduces the power loss according to a load pattern is an important issue. Mathematically, the network reconfiguration system is a nonlinear programming problem with integer variables. One three-feeder network reconfiguration system from the literature is researched by the proposed backtracking VSHDE method and simulated annealing (SA. Numerical results show that the perfrmance of the proposed method outperformed the SA method.

GRAMSCI E A FILOSOFIA POLÍTICA DE SEU TEMPO

OpenAIRE

José Carlos Freire

2011-01-01

O presente artigo procura refletir sobre o modo pelo qual Gramsci debate com os autores de seu tempo, a fim de recolocar o marxismo no terreno da história e da dialética. Tomamos como referência o confronto de Gramsci com o neo-idealismo italiano, representado por Benedetto Croce, e com o marxismo economicista, representado por Nicolai Bukharin. Com isso, procuraremos analisar se Gramsci seria autenticamente um marxista ou, dito de outro modo, até que ponto ele teria se afastado de Marx pela ...

Relationship between exercise heart rate and music tempo preference

OpenAIRE

Karageorghis, CI; Jones, L; Low, DC

2006-01-01

The present study examined the predicted positive and linear relationship (Iwanaga, 1995a,1995b) between exercise heart rate and music tempo preference. Initially, 128 undergraduates (M 3 age = 20.0 years, SD = 0.9 years) were surveyed to establish their three favorite music artists of all time. A separate experimental group of 29 undergraduates (M age = 20.3 years, SD = 1.2 years) selected the music of a single artist from a choice of the three highest-rated artists from the earlier survey. ...

Attractive evolutionary equilibria

OpenAIRE

Roorda, Berend; Joosten, Reinoud

2011-01-01

We present attractiveness, a refinement criterion for evolutionary equilibria. Equilibria surviving this criterion are robust to small perturbations of the underlying payoff system or the dynamics at hand. Furthermore, certain attractive equilibria are equivalent to others for certain evolutionary dynamics. For instance, each attractive evolutionarily stable strategy is an attractive evolutionarily stable equilibrium for certain barycentric ray-projection dynamics, and vice versa.

TEMPO-oxidized Konjac glucomannan as appliance for the preparation of hard capsules

NARCIS (Netherlands)

Chen, Yuying; Zhao, Huiying; Liu, Xianwu; Li, Zusen; Liu, Bin; Wu, Jiande; Shi, Mengxuan; Norde, Willem; Li, Yuan

2016-01-01

TEMPO-oxidized Konjac glucomannan (OKGM) was developed as new material for preparing vegetarian hard capsules. OKGM of different degrees of oxidation: DO30%, DO50%, and DO80% were prepared to select optimum DO for capsule formation. FT-IR results proved that the primary alcohol groups on KGM were

Effects of Articulation Styles on Perception of Modulated Tempos in Violin Excerpts

Science.gov (United States)

Geringer, John M.; Madsen, Clifford K.; Macleod, Rebecca B.

2007-01-01

We investigated effects of legato, staccato and pizzicato articulation styles on the perception of modulated tempos. Seventy-two music majors served as participants. Two solo violin excerpts were chosen with contrasting rhythmic rates and were recorded in all three articulation styles. Examples were presented to listeners in three conditions of…

Practical aerobic oxidations of alcohols and amines with homogeneous copper/TEMPO and related catalyst systems.

Science.gov (United States)

Ryland, Bradford L; Stahl, Shannon S

2014-08-18

Oxidations of alcohols and amines are common reactions in the synthesis of organic molecules in the laboratory and industry. Aerobic oxidation methods have long been sought for these transformations, but few practical methods exist that offer advantages over traditional oxidation methods. Recently developed homogeneous Cu/TEMPO (TEMPO = 2,2,6,6-tetramethylpiperidinyl-N-oxyl) and related catalyst systems appear to fill this void. The reactions exhibit high levels of chemoselectivity and broad functional-group tolerance, and they often operate efficiently at room temperature with ambient air as the oxidant. These advances, together with their historical context and recent applications, are highlighted in this Minireview. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Evolutionary principles and their practical application.

Science.gov (United States)

Hendry, Andrew P; Kinnison, Michael T; Heino, Mikko; Day, Troy; Smith, Thomas B; Fitt, Gary; Bergstrom, Carl T; Oakeshott, John; Jørgensen, Peter S; Zalucki, Myron P; Gilchrist, George; Southerton, Simon; Sih, Andrew; Strauss, Sharon; Denison, Robert F; Carroll, Scott P

2011-03-01

Evolutionary principles are now routinely incorporated into medicine and agriculture. Examples include the design of treatments that slow the evolution of resistance by weeds, pests, and pathogens, and the design of breeding programs that maximize crop yield or quality. Evolutionary principles are also increasingly incorporated into conservation biology, natural resource management, and environmental science. Examples include the protection of small and isolated populations from inbreeding depression, the identification of key traits involved in adaptation to climate change, the design of harvesting regimes that minimize unwanted life-history evolution, and the setting of conservation priorities based on populations, species, or communities that harbor the greatest evolutionary diversity and potential. The adoption of evolutionary principles has proceeded somewhat independently in these different fields, even though the underlying fundamental concepts are the same. We explore these fundamental concepts under four main themes: variation, selection, connectivity, and eco-evolutionary dynamics. Within each theme, we present several key evolutionary principles and illustrate their use in addressing applied problems. We hope that the resulting primer of evolutionary concepts and their practical utility helps to advance a unified multidisciplinary field of applied evolutionary biology.

The evolutionary origin and significance of Menopause

Science.gov (United States)

Pollycove, Ricki; Naftolin, Frederick; Simon, James A.

2010-01-01

Contemporary human females have long life expectancy (81y US), especially relative to age at menopause (51y US). Menopause is a consequence of reproductive aging and follicular depletion (ovarian failure), yielding very low circulating estrogen* serum concentrations and biologically disadvantageous metabolic alterations. Stated in terms of antagonistic pleiotropy, the ongoing hypoestrogenic endocrine environment, beneficial during lactation, results in acceleration of several age-related health conditions following menopause (i.e. late postmenopausal osteoporosis, cardiovascular disease and cognitive decline). In contrast, the complex hypoestrogenic hormonal milieu present during postpartum lactation provides biologic advantages to both mother and newborn. The lactational hormonal milieu causes symptoms similar to those of the late perimenopause and early postmenopause, prompting theories for their biologic selective advantage. The precepts of evolutionary medicine encourage a reassessment of hormone therapy. Based on data presented, the authors propose additional opportunities for disease prevention and morbidity reduction in postmenopausal women. PMID:21252729

A filled duration illusion in music: Effects of metrical subdivision on the perception and production of beat tempo.

Science.gov (United States)

Repp, Bruno H; Bruttomesso, Meijin

2010-01-13

This study replicates and extends previous findings suggesting that metrical subdivision slows the perceived beat tempo (Repp, 2008). Here, musically trained participants produced the subdivisions themselves and were found to speed up, thus compensating for the perceived slowing. This was shown in a synchronization-continuation paradigm (Experiment 1) and in a reproduction task (Experiment 2a). Participants also judged the tempo of a subdivided sequence as being slower than that of a preceding simple beat sequence (Experiment 2b). Experiment 2 also included nonmusician participants, with similar results. Tempo measurements of famous pianists' recordings of two variation movements from Beethoven sonatas revealed a strong tendency to play the first variation (subdivided beats) faster than the theme (mostly simple beats). A similar tendency was found in musicians' laboratory performances of a simple theme and variations, despite instruc-tions to keep the tempo constant (Experiment 3a). When playing melodic sequences in which only one of three beats per measure was subdivided, musicians tended to play these beats faster and to perceive them as longer than adjacent beats, and they played the whole sequence faster than a sequence without any subdivisions (Experiments 3b and 3c). The results amply demonstrate a filled duration illusion in rhythm perception and music performance: Intervals containing events seem longer than empty intervals and thus must be shortened to be perceived as equal in duration.

A concepção do tempo em Bergson e sua relação com a teoria da relatividade de Einstein

OpenAIRE

Daniel Siqueira Pereira

2008-01-01

A presente dissertação trata da relação entre o conceito de tempo tal como foi pensado pelo filósofo francês Henri Bergson (1859-1941) e pelo físico alemão Albert Einstein (1879-1955). Ambos foram contemporâneos e tiveram a chance de confrontar suas opiniões discordantes sobre a natureza do tempo. Em seu polêmico ensaio Duração e Simultaneidade (1922), Bergson expôs sua teoria sobre tempo, pensado enquanto duração, já levando em conta a teoria da relatividade de Einstein. O ob...

A STUDY OF TIME MANAGEMENT EFFECTIVE AS A TOOL FOR INCREASED PRODUCTIVITY AND WORK-LIFE BALANCE AND PERSONAL ADMINISTRAÇÃO DO TEMPO: UM ESTUDO SOBRE A GESTÃO EFICAZ DO TEMPO COMO FERRAMENTA PARA O AUMENTO DA PRODUTIVIDADE E WORK LIFE BALANCE

Directory of Open Access Journals (Sweden)

Maria do Carmo Ferreira Lima

2011-05-01

Full Text Available

Time Management has been a topic of high relevance, and subject of extensive discussion, especially in the corporate world. Since the first studies of Classical Administration, as for example the "Motion and Time Study," conducted by Taylor, at the time of the Industrial Revolution, through the Technological Revolution in the early 1990s until today, there have always been questions about how it would be possible to better manage time. The challenge is not to manage time, but relationships managed by professionals. The aim of this study was to understand how the adoption of techniques of Time Management can serve as a tool for increasing productivity and balance the career versus personal life. The literature review was supported by a survey in two stages. The first step applied as descriptive, with the intention of identifying what were called "time wasters" most common within the sample surveyed and diagnose the profile time management of all the participants. In the later stage, we performed a case study, in which, for a period of 30 days, voluntary participants were instructed to use some tools such as software and forms available on the market for organization and effective time management. The results proved that a considerable number of people do not know how to manage and take their time and suffering from the negative effects of work overload and lack of motivation that is constantly tied to this scenario. The outcome of the case study found that the tools of organization and time management are available and promote good improvement in how you manage time. But you need commitment and discipline that uses these mechanisms, since the change in how they manage their time is primarily a behavioral change.

A Administração do Tempo vem sendo um tema de alta relevância, e muito discutido, principalmente no mundo corporativo. Desde os primeiros estudos da Administração Clássica, como o �

Poesia e cinema: uma forma de representação do mundo e do tempo

Directory of Open Access Journals (Sweden)

Ana Lúcia Costa Barbosa

2016-09-01

Full Text Available Este artigo visa a analisar a técnica compositiva de três poemas de Carlos Drummond de Andrade, a saber: “Consideração do poema” “Procura de poesia” e “Canto ao homem do povo Charlie Chaplin”, presentes em A rosa do povo, escrito entre 1943 a 1945. Os dois primeiros poemas mereceram de diferentes críticos análises diversas. Alguns assumem posições divergentes, reconhecendo-se no primeiro a função predominante da linguagem, enquanto o outro estaria mais atrelado ao compromisso social. Outras tendências críticas defendem que os dois poemas compõem um todo coerente, estando, ambos, erigidos de acordo com a concepção dialética de gênero lírico. Propõe-se, também, a discutir as relações entre poesia e cinema, entendendo-os como formas de representação cultural de um tempo histórico. O “Canto ao homem do povo Charlie Chaplin” estabelece um diálogo com seu tempo, abordando temas como a luta pela sobrevivência, o protesto contra a fome e a brutalidade dos tempos modernos.

Utilização do TEMPO (N-oxil-2,2,6,6-tetrametilpiperidina na oxidação de álcoois primários e secundários The use of TEMPO (2,2,6,6-tetramethylpiperidine-N-oxyl for the oxidation of primary and secondary alcohols

Directory of Open Access Journals (Sweden)

Marcus Vinícius Nora de Souza

2004-04-01

Full Text Available The oxidation of alcohols to obtain ketones, aldehydes or carboxylic acids is a fundamental transformation in organic synthesis and many reagents are known for these conversions. However, there is still a demand for mild and selective reagents for the oxidation of alcohols in the presence of other functional groups. As an alternative, the nitroxyl radical TEMPO (2,2,6,6-tetramethylpiperidine-N-oxyl has been demonstrated to be a useful reagent for the transformation of alcohols. The oxidation of alcohols using TEMPO is often efficient, fast, selective, made in mild conditions and can tolerate sensitive functional groups. In this article we report different methodologies using TEMPO in the oxidation of alcohols.

Plants, Pollution and Public Engagement with Atmospheric Chemistry: Sharing the TEMPO Story Through Ozone Garden Activities

Science.gov (United States)

Reilly, L. G.; Pippin, M. R.; Malick, E.; Summers, D.; Dussault, M. E.; Wright, E. A.; Skelly, J.

2016-12-01

What do a snap-bean plant and a future NASA satellite instrument named TEMPO have in common? They are both indicators of the quality of the air we breathe. Scientists, educators, and museum and student collaborators of the Tropospheric Emissions: Monitoring Pollution (TEMPO) instrument team are developing a program model to engage learners of all ages via public ozone garden exhibits and associated activities. TEMPO, an ultraviolet and visible spectroscopy instrument due for launch on a geostationary host satellite between 2019 and 2021, will scan North America hourly to measure the major elements in the tropospheric ozone chemistry cycle, providing near real-time data with high temporal and spatial resolution. The TEMPO mission provides a unique opportunity to share the story of the effects of air quality on living organisms. A public ozone garden exhibit affords an accessible way to understand atmospheric science through a connection with nature, while providing a visual representation of the impact of ozone pollution on living organisms. A prototype ozone garden exhibit was established at the Virginia Living Museum in partnership with NASA Langley, and has served as a site to formatively evaluate garden planting and exhibit display protocols, hands-on interpretive activities, and citizen science data collection protocols for learners as young as 3 to 10 as well as older adults. The fun and engaging activities, optimized for adult-child interaction in informal or free-choice learning environments, are aimed at developing foundational science skills such as observing, comparing, classifying, and collecting and making sense of data in the context of thinking about air quality - all NGSS-emphasized scientific practices, as well as key capabilities for future contributing members of the citizen science community. As the launch of TEMPO approaches, a major public engagement effort will include disseminating this ozone garden exhibit and program model to a network of

Musicians are more consistent: Gestural cross-modal mappings of pitch, loudness and tempo in real-time

Science.gov (United States)

Küssner, Mats B.; Tidhar, Dan; Prior, Helen M.; Leech-Wilkinson, Daniel

2014-01-01

Cross-modal mappings of auditory stimuli reveal valuable insights into how humans make sense of sound and music. Whereas researchers have investigated cross-modal mappings of sound features varied in isolation within paradigms such as speeded classification and forced-choice matching tasks, investigations of representations of concurrently varied sound features (e.g., pitch, loudness and tempo) with overt gestures—accounting for the intrinsic link between movement and sound—are scant. To explore the role of bodily gestures in cross-modal mappings of auditory stimuli we asked 64 musically trained and untrained participants to represent pure tones—continually sounding and concurrently varied in pitch, loudness and tempo—with gestures while the sound stimuli were played. We hypothesized musical training to lead to more consistent mappings between pitch and height, loudness and distance/height, and tempo and speed of hand movement and muscular energy. Our results corroborate previously reported pitch vs. height (higher pitch leading to higher elevation in space) and tempo vs. speed (increasing tempo leading to increasing speed of hand movement) associations, but also reveal novel findings pertaining to musical training which influenced consistency of pitch mappings, annulling a commonly observed bias for convex (i.e., rising–falling) pitch contours. Moreover, we reveal effects of interactions between musical parameters on cross-modal mappings (e.g., pitch and loudness on speed of hand movement), highlighting the importance of studying auditory stimuli concurrently varied in different musical parameters. Results are discussed in light of cross-modal cognition, with particular emphasis on studies within (embodied) music cognition. Implications for theoretical refinements and potential clinical applications are provided. PMID:25120506

Musicians are more consistent: Gestural cross-modal mappings of pitch, loudness and tempo in real-time

Directory of Open Access Journals (Sweden)

Mats B. Küssner

2014-07-01

Full Text Available Cross-modal mappings of auditory stimuli reveal valuable insights into how humans make sense of sound and music. Whereas researchers have investigated cross-modal mappings of sound features varied in isolation within paradigms such as speeded classification and forced-choice matching tasks, investigations of representations of concurrently varied sound features (e.g., pitch, loudness and tempo with overt gestures—accounting for the intrinsic link between movement and sound—are scant. To explore the role of bodily gestures in cross-modal mappings of auditory stimuli we asked sixty-four musically trained and untrained participants to represent pure tones—continually sounding and concurrently varied in pitch, loudness and tempo—with gestures while the sound stimuli were played. We hypothesised musical training to lead to more consistent mappings between pitch and height, loudness and distance/height, and tempo and speed of hand movement and muscular energy.Our results corroborate previously reported pitch vs. height (higher pitch leading to higher elevation in space and tempo vs. speed (increasing tempo leading to increasing speed of hand movement associations, but also reveal novel findings pertaining to musical training which influenced consistency of pitch mappings, annulling a commonly observed bias for convex (i.e. rising-falling pitch contours. Moreover, we reveal effects of interactions between musical parameters on cross-modal mappings (e.g., pitch and loudness on speed of hand movement, highlighting the importance of studying auditory stimuli concurrently varied in different musical parameters. Results are discussed in light of cross-modal cognition, with particular emphasis on studies within (embodied music cognition. Implications for theoretical refinements and potential clinical applications are provided.

Concentrações salinas combinadas com tempos de hidratação: efeito no tempo de cocção em feijão Salts concentrations in combination with soaking time: effect in bean cooking time

Directory of Open Access Journals (Sweden)

Juliano Garcia Bertoldo

2010-06-01

Full Text Available Este trabalho teve como objetivo investigar o efeito da adição de diferentes doses de NaCl na água de hidratação, durante diferentes tempos, buscando uma redução no tempo de cocção. O Brasil, embora seja considerado um grande produtor e um dos maiores consumidores de feijão, está reduzindo gradativamente o consumo. Sendo assim, é necessário dispor de técnicas que facilitem o preparo do feijão, podendo dessa forma reverter a tendência de consumo e como consequência incentivar a produção. O experimento foi conduzido na área experimental do Instituto de Melhoramento e Genética Molecular da UDESC - IMEGEM, em Lages - SC. Foram avaliados os efeitos de três concentrações de NaCL (0, 50 e 125 g.L-1 em dois genótipos de feijão (Pérola e IPR Uirapuru hidratados durante três tempos (0,5, 9 e 18 horas. Os resultados revelaram um efeito significativo das doses de NaCl na redução do tempo de cocção. A adição de 56,50 g.L-1 de NaCl foi suficiente para reduzir significativamente o tempo de cocção. A hidratação dos grãos de feijão propiciou a redução no tempo de cocção, sendo necessárias 12,5 horas para a máxima hidratação, independente dos genótipos avaliados.This study aimed to investigate the effect of adding different doses of NaCl in hydration water, during different times, in order to reduce cooking time. Although considered a major producer and one of the largest bean consumers, Brazil has been experiencing a gradual decrease in consumption. Therefore, it is necessary to facilitate the preparation of beans to increase its consumption and production. This study was conducted at the experimental area of the Institute of Molecular Genetics and Plant Breeding at UDESC - IMEGEM, in the city of Lages, SC-Brazil. We evaluated the effect of three doses of NaCL (0, 50 e 125 g L-1 in two genotypes of beans (Pérola and IPR Uirapuru, hydrated at three different times (0.5, 9, and 18 hours. The results revealed a

Accelerated evolution of the ASPM gene controlling brain size begins prior to human brain expansion.

Directory of Open Access Journals (Sweden)

Natalay Kouprina

2004-05-01

Full Text Available Primary microcephaly (MCPH is a neurodevelopmental disorder characterized by global reduction in cerebral cortical volume. The microcephalic brain has a volume comparable to that of early hominids, raising the possibility that some MCPH genes may have been evolutionary targets in the expansion of the cerebral cortex in mammals and especially primates. Mutations in ASPM, which encodes the human homologue of a fly protein essential for spindle function, are the most common known cause of MCPH. Here we have isolated large genomic clones containing the complete ASPM gene, including promoter regions and introns, from chimpanzee, gorilla, orangutan, and rhesus macaque by transformation-associated recombination cloning in yeast. We have sequenced these clones and show that whereas much of the sequence of ASPM is substantially conserved among primates, specific segments are subject to high Ka/Ks ratios (nonsynonymous/synonymous DNA changes consistent with strong positive selection for evolutionary change. The ASPM gene sequence shows accelerated evolution in the African hominoid clade, and this precedes hominid brain expansion by several million years. Gorilla and human lineages show particularly accelerated evolution in the IQ domain of ASPM. Moreover, ASPM regions under positive selection in primates are also the most highly diverged regions between primates and nonprimate mammals. We report the first direct application of TAR cloning technology to the study of human evolution. Our data suggest that evolutionary selection of specific segments of the ASPM sequence strongly relates to differences in cerebral cortical size.

Acceleration performance of individual European sea bass Dicentrarchus labrax measured with a sprint performance chamber: comparison with high-speed cinematography and correlates with ecological performance.

Science.gov (United States)

Vandamm, Joshua P; Marras, Stefano; Claireaux, Guy; Handelsman, Corey A; Nelson, Jay A

2012-01-01

Locomotor performance can influence the ecological and evolutionary success of a species. For fish, favorable outcomes of predator-prey encounters are often presumably due to robust acceleration ability. Although escape-response or "fast-start" studies utilizing high-speed cinematography are prevalent, little is known about the contribution of relative acceleration performance to ecological or evolutionary success in a species. This dearth of knowledge may be due to the time-consuming nature of analyzing film, which imposes a practical limit on sample sizes. Herein, we present a high-throughput potential alternative for measuring fish acceleration performance using a sprint performance chamber (SPC). The acceleration performance of a large number of juvenile European sea bass (Dicentrarchus labrax) from two populations was analyzed. Animals from both hatchery and natural ontogenies were assessed, and animals of known acceleration ability had their ecological performance measured in a mesocosm environment. Individuals from one population also had their acceleration performance assessed by both high-speed cinematography and an SPC. Acceleration performance measured in an SPC was lower than that measured by classical high-speed video techniques. However, short-term repeatability and interindividual variation of acceleration performance were similar between the two techniques, and the SPC recorded higher sprint swimming velocities. Wild fish were quicker to accelerate in an SPC and had significantly greater accelerations than all groups of hatchery-raised fish. Acceleration performance had no significant effect on ecological performance (as assessed through animal growth and survival in the mesocosms). However, it is worth noting that wild animals did survive predation in the mesocosm better than farmed ones. Moreover, the hatchery-originated fish that survived the mesocosm experiment, when no predators were present, displayed significantly increased acceleration

The currency and tempo of extinction.

Science.gov (United States)

Regan, H M; Lupia, R; Drinnan, A N; Burgman, M A

2001-01-01

This study examines estimates of extinction rates for the current purported biotic crisis and from the fossil record. Studies that compare current and geological extinctions sometimes use metrics that confound different sources of error and reflect different features of extinction processes. The per taxon extinction rate is a standard measure in paleontology that avoids some of the pitfalls of alternative approaches. Extinction rates reported in the conservation literature are rarely accompanied by measures of uncertainty, despite many elements of the calculations being subject to considerable error. We quantify some of the most important sources of uncertainty and carry them through the arithmetic of extinction rate calculations using fuzzy numbers. The results emphasize that estimates of current and future rates rely heavily on assumptions about the tempo of extinction and on extrapolations among taxa. Available data are unlikely to be useful in measuring magnitudes or trends in current extinction rates.

Algorithmic Mechanism Design of Evolutionary Computation.

Science.gov (United States)

Pei, Yan

2015-01-01

We consider algorithmic design, enhancement, and improvement of evolutionary computation as a mechanism design problem. All individuals or several groups of individuals can be considered as self-interested agents. The individuals in evolutionary computation can manipulate parameter settings and operations by satisfying their own preferences, which are defined by an evolutionary computation algorithm designer, rather than by following a fixed algorithm rule. Evolutionary computation algorithm designers or self-adaptive methods should construct proper rules and mechanisms for all agents (individuals) to conduct their evolution behaviour correctly in order to definitely achieve the desired and preset objective(s). As a case study, we propose a formal framework on parameter setting, strategy selection, and algorithmic design of evolutionary computation by considering the Nash strategy equilibrium of a mechanism design in the search process. The evaluation results present the efficiency of the framework. This primary principle can be implemented in any evolutionary computation algorithm that needs to consider strategy selection issues in its optimization process. The final objective of our work is to solve evolutionary computation design as an algorithmic mechanism design problem and establish its fundamental aspect by taking this perspective. This paper is the first step towards achieving this objective by implementing a strategy equilibrium solution (such as Nash equilibrium) in evolutionary computation algorithm.

Evolutionary rescue: linking theory for conservation and medicine.

Science.gov (United States)

Alexander, Helen K; Martin, Guillaume; Martin, Oliver Y; Bonhoeffer, Sebastian

2014-12-01

Evolutionary responses that rescue populations from extinction when drastic environmental changes occur can be friend or foe. The field of conservation biology is concerned with the survival of species in deteriorating global habitats. In medicine, in contrast, infected patients are treated with chemotherapeutic interventions, but drug resistance can compromise eradication of pathogens. These contrasting biological systems and goals have created two quite separate research communities, despite addressing the same central question of whether populations will decline to extinction or be rescued through evolution. We argue that closer integration of the two fields, especially of theoretical understanding, would yield new insights and accelerate progress on these applied problems. Here, we overview and link mathematical modelling approaches in these fields, suggest specific areas with potential for fruitful exchange, and discuss common ideas and issues for empirical testing and prediction.

The acceleration of the masculine in early-twentieth-century Berlin.

Science.gov (United States)

Prickett, David James

2012-01-01

In early-twentieth-century Berlin, agents of speed and industrialisation, such as the railway, contributed to the seemingly unbridled velocity of urban life. Doctors and cultural critics took an ambivalent stance toward the impact of speed and technology on the human body. Critics argued that these factors, in conjunction with sexual excess and prostitution, accelerated the sexual maturation of young men, thereby endangering ‘healthy’ male sexuality. This comparison of Hans Ostwald's socio-literary study Dunkle Winkel in Berlin (1904) with Georg Buschan's sexual education primer Vom Jüngling zum Mann (1911) queries the extent to which speed shaped the understanding of ‘the masculine’ in pre-World-War-I Germany. The essay thus examines Ostwald's and Buschan's arguments and postulates that speed in the city (Berlin) can be seen as a feminised, sexualised force that determined sex in the city. According to this reading, the homosexual urban dandy resisted the accelerated modernist urban tempo, whereas the heterosexual man and hegemonic, heteronormative masculinity yielded to speed. ‘“Das Verhältnis”’ became a fleeting, momentary alternative to stable marital relationships, which in turn contributed to the general ‘crisis’ of – and in– masculinity in early-twentieth-century Berlin.

Efetividade de um protocolo assistencial para redução do tempo porta-balão da angioplastia primária

Directory of Open Access Journals (Sweden)

Luis Cláudio Lemos Correia

2013-07-01

Full Text Available FUNDAMENTO: Tempo porta-balão adequado (< 120 minutos é a condição necessária para que a eficácia da angioplastia primária no infarto se traduza em efetividade. OBJETIVO: Descrever a efetividade de um protocolo de qualidade assistencial para redução do tempo porta-balão. MÉTODOS: Entre maio de 2010 e agosto de 2012, foram analisados todos os indivíduos que realizaram angioplastia primária em nosso hospital. O momento porta foi registrado eletronicamente, pela retirada de senha para atendimento na emergência, o que antecede o preenchimento da ficha e a triagem. O momento balão foi definido como o início da abertura da artéria (passagem do primeiro dispositivo. Os primeiros 5 meses de monitoramento corresponderam ao período pré-implementação do protocolo. O protocolo se constituiu de definição do fluxo de ações, desde a chegada do paciente ao hospital, a sensibilização da equipe quanto à priorização do tempo e a apresentação periódica de parecer dos resultados e de possíveis inadequações. RESULTADOS: Foram avaliados 50 indivíduos, divididos em cinco grupos de 10 pacientes sequenciais (um grupo pré e quatro grupos pós-protocolo. O tempo porta-balão referente aos 10 casos registrados antes da implementação do protocolo foi de 200 ± 77 minutos. Após a implementação do protocolo, houve progressiva melhora do tempo porta-balão, para 142 ± 78 minutos nos 10 primeiros pacientes, seguida de 150±50 minutos, 131±37 minutos e, finalmente, 116 ± 29 minutos no três grupos sequenciais de 10 pacientes, respectivamente. Regressão linear entre pacientes sequenciais e tempo porta-balão (r = - 0,41 evidenciou coeficiente de regressão de - 1,74 minutos. CONCLUSÃO: A implementação do protocolo se mostrou efetiva na redução do tempo porta-balão.

Injectable TEMPO-oxidized nanofibrillated cellulose/biphasic calcium phosphate hydrogel for bone regeneration.

Science.gov (United States)

Safwat, Engie; Hassan, Mohammad L; Saniour, Sayed; Zaki, Dalia Yehia; Eldeftar, Mervat; Saba, Dalia; Zazou, Mohamed

2018-05-01

Nanofibrillated cellulose, obtained from rice straw agricultural wastes was used as a substrate for the preparation of a new injectable and mineralized hydrogel for bone regeneration. Tetramethyl pyridine oxyl (TEMPO) oxidized nanofibrillated cellulose, was mineralized through the incorporation of a prepared and characterized biphasic calcium phosphate at a fixed ratio of 50 wt%. The TEMPO-oxidized rice straw nanofibrillated cellulose was characterized using transmission electron microscopy, Fourier transform infrared, and carboxylic content determination. The injectability and viscosity of the prepared hydrogel were evaluated using universal testing machine and rheometer testing, respectively. Cytotoxicity and alkaline phosphatase level tests on osteoblast like-cells for in vitro assessment of the biocompatibility were investigated. Results revealed that the isolated rice straw nanofibrillated cellulose is a nanocomposite of the cellulose nanofibers and silica nanoparticles. Rheological properties of the tested materials are suitable for use as injectable material and of nontoxic effect on osteoblast-like cells, as revealed by the positive alkaline phosphate assay. However, nanofibrillated cellulose/ biphasic calcium phosphate hydrogel showed higher cytotoxicity and lower bioactivity test results when compared to that of nanofibrillated cellulose.

Evolutionary Explanations of Eating Disorders

Directory of Open Access Journals (Sweden)

Igor Kardum

2008-12-01

Full Text Available This article reviews several most important evolutionary mechanisms that underlie eating disorders. The first part clarifies evolutionary foundations of mental disorders and various mechanisms leading to their development. In the second part selective pressures and evolved adaptations causing contemporary epidemic of obesity as well as differences in dietary regimes and life-style between modern humans and their ancestors are described. Concerning eating disorders, a number of current evolutionary explanations of anorexia nervosa are presented together with their main weaknesses. Evolutionary explanations of eating disorders based on the reproductive suppression hypothesis and its variants derived from kin selection theory and the model of parental manipulation were elaborated. The sexual competition hypothesis of eating disorder, adapted to flee famine hypothesis as well as explanation based on the concept of social attention holding power and the need to belonging were also explained. The importance of evolutionary theory in modern conceptualization and research of eating disorders is emphasized.

The citation field of evolutionary economics

NARCIS (Netherlands)

Dolfsma, Wilfred; Leydesdorff, Loet

2010-01-01

Evolutionary economics has developed into an academic field of its own, institutionalized around, amongst others, the Journal of Evolutionary Economics (JEE). This paper analyzes the way and extent to which evolutionary economics has become an interdisciplinary journal, as its aim was: a journal

Qualidade fisiológica de sementes de guanxuma em influência do envelhecimento acelerado e da luz = Influence of accelerated aging and light on the physiological quality of arrowleaf sida seeds

Directory of Open Access Journals (Sweden)

Denise Bruginski de Carvalho

2009-07-01

Full Text Available O objetivo deste trabalho foi determinar o efeito do envelhecimento acelerado e da presença da luz na qualidade fisiológica de sementes de guanxuma (Sida rhombifolia L.. Foram estudados quatro tempos de envelhecimento acelerado (0, 24, 48 e 72h e a presença ou ausência de luz no teste de germinação. O delineamento experimental adotado foi em blocos casualizados num esquema fatorial 4 x 2, com três repetições. Adotou-se o método de germinação sobre papel em caixa de plástico (Gerbox à temperatura de 25°C. Analisaram-se as variáveis porcentagem de germinação, índice de velocidade de germinação(IVG, tempo médio para germinação (TMG, velocidade média de germinação (VMG e entropia. As avaliações foram realizadas durante 63 dias após a instalação do teste. A ausência de luz favoreceu a germinação e o IVG das sementes de guanxuma. O TMG e a entropiadiminuíram e a VMG aumentou com o aumento do tempo de envelhecimento acelerado e não foram influenciados pela luz. Na presença de luz, a germinação e o IVG foram reduzidos com tempos de envelhecimento acelerado mais longos. Conclui-se que o envelhecimento acelerado de sementes de guanxuma por até 72h proporcionou aumento na qualidade fisiológica das sementes submetidas à germinação no escuro.The objective of this study was to determine the effect ofaccelerated aging and presence of light on the physiological quality of arrowleaf sida (Sida rhombifolia L. seeds. Four accelerated aging times (0, 24, 48 and 72 hours, as well as the presence or absence of light during germination test, were evaluated by using a randomizedblock design, with a 4 x 2 factorial scheme and three replications. Seeds were germinated in germination boxes (Gerbox lined with paper, at 25°C. The variables analyzed were: germination percentage, germination speed index (GSI, average germination time (AGT,average germination speed (AGS and entropy. Evaluations were made 63 days after installation

Towards a mechanistic foundation of evolutionary theory.

Science.gov (United States)

Doebeli, Michael; Ispolatov, Yaroslav; Simon, Burt

2017-02-15

Most evolutionary thinking is based on the notion of fitness and related ideas such as fitness landscapes and evolutionary optima. Nevertheless, it is often unclear what fitness actually is, and its meaning often depends on the context. Here we argue that fitness should not be a basal ingredient in verbal or mathematical descriptions of evolution. Instead, we propose that evolutionary birth-death processes, in which individuals give birth and die at ever-changing rates, should be the basis of evolutionary theory, because such processes capture the fundamental events that generate evolutionary dynamics. In evolutionary birth-death processes, fitness is at best a derived quantity, and owing to the potential complexity of such processes, there is no guarantee that there is a simple scalar, such as fitness, that would describe long-term evolutionary outcomes. We discuss how evolutionary birth-death processes can provide useful perspectives on a number of central issues in evolution.

Heritable symbiosis: The advantages and perils of an evolutionary rabbit hole.

Science.gov (United States)

Bennett, Gordon M; Moran, Nancy A

2015-08-18

Many eukaryotes have obligate associations with microorganisms that are transmitted directly between generations. A model for heritable symbiosis is the association of aphids, a clade of sap-feeding insects, and Buchnera aphidicola, a gammaproteobacterium that colonized an aphid ancestor 150 million years ago and persists in almost all 5,000 aphid species. Symbiont acquisition enables evolutionary and ecological expansion; aphids are one of many insect groups that would not exist without heritable symbiosis. Receiving less attention are potential negative ramifications of symbiotic alliances. In the short run, symbionts impose metabolic costs. Over evolutionary time, hosts evolve dependence beyond the original benefits of the symbiosis. Symbiotic partners enter into an evolutionary spiral that leads to irreversible codependence and associated risks. Host adaptations to symbiosis (e.g., immune-system modification) may impose vulnerabilities. Symbiont genomes also continuously accumulate deleterious mutations, limiting their beneficial contributions and environmental tolerance. Finally, the fitness interests of obligate heritable symbionts are distinct from those of their hosts, leading to selfish tendencies. Thus, genes underlying the host-symbiont interface are predicted to follow a coevolutionary arms race, as observed for genes governing host-pathogen interactions. On the macroevolutionary scale, the rapid evolution of interacting symbiont and host genes is predicted to accelerate host speciation rates by generating genetic incompatibilities. However, degeneration of symbiont genomes may ultimately limit the ecological range of host species, potentially increasing extinction risk. Recent results for the aphid-Buchnera symbiosis and related systems illustrate that, whereas heritable symbiosis can expand ecological range and spur diversification, it also presents potential perils.

Evolutionary thinking: "A conversation with Carter Phipps about the role of evolutionary thinking in modern culture".

Science.gov (United States)

Hunt, Tam

2014-12-01

Evolution as an idea has a lengthy history, even though the idea of evolution is generally associated with Darwin today. Rebecca Stott provides an engaging and thoughtful overview of this history of evolutionary thinking in her 2013 book, Darwin's Ghosts: The Secret History of Evolution. Since Darwin, the debate over evolution-both how it takes place and, in a long war of words with religiously-oriented thinkers, whether it takes place-has been sustained and heated. A growing share of this debate is now devoted to examining how evolutionary thinking affects areas outside of biology. How do our lives change when we recognize that all is in flux? What can we learn about life more generally if we study change instead of stasis? Carter Phipps' book, Evolutionaries: Unlocking the Spiritual and Cultural Potential of Science's Greatest Idea, delves deep into this relatively new development. Phipps generally takes as a given the validity of the Modern Synthesis of evolutionary biology. His story takes us into, as the subtitle suggests, the spiritual and cultural implications of evolutionary thinking. Can religion and evolution be reconciled? Can evolutionary thinking lead to a new type of spirituality? Is our culture already being changed in ways that we don't realize by evolutionary thinking? These are all important questions and Phipps book is a great introduction to this discussion. Phipps is an author, journalist, and contributor to the emerging "integral" or "evolutionary" cultural movement that combines the insights of Integral Philosophy, evolutionary science, developmental psychology, and the social sciences. He has served as the Executive Editor of EnlightenNext magazine (no longer published) and more recently is the co-founder of the Institute for Cultural Evolution, a public policy think tank addressing the cultural roots of America's political challenges. What follows is an email interview with Phipps.

Where Evolutionary Psychology Meets Cognitive Neuroscience: A Précis to Evolutionary Cognitive Neuroscience1

Directory of Open Access Journals (Sweden)

Austen L. Krill

2007-01-01

Full Text Available Cognitive neuroscience, the study of brain-behavior relationships, has long attempted to map the brain. The discipline is flourishing, with an increasing number of functional neuroimaging studies appearing in the scientific literature daily. Unlike biology and even psychology, the cognitive neurosciences have only recently begun to apply evolutionary meta-theory and methodological guidance. Approaching cognitive neuroscience from an evolutionary perspective allows scientists to apply biologically based theoretical guidance to their investigations and can be conducted in both humans and nonhuman animals. In fact, several investigations of this sort are underway in laboratories around the world. This paper and two new volumes (Platek, Keenan, and Shackelford [Eds.], 2007; Platek and Shackelford [Eds.], under contract represent the first formal attempts to document the burgeoning field of evolutionary cognitive neuroscience. Here, we briefly review the current state of the science of evolutionary cognitive neuroscience, the methods available to the evolutionary cognitive neuroscientist, and what we foresee as the future directions of the discipline.

The tempo and mode of barnacle evolution

DEFF Research Database (Denmark)

Pérez-Losada, Marcos; Harp, Margaret; Høeg, Jens T

2008-01-01

(outgroup) species representing almost all the Thoracica families to assess the tempo and mode of barnacle evolution. Using phylogenetic methods of maximum parsimony, maximum likelihood, and Bayesian inference and 14 fossil calibrations, we found that: (1) Iblomorpha form a monophyletic group; (2......) pedunculated barnacles without shell plates (Heteralepadomorpha) are not ancestral, but have evolved, at least twice, from plated forms; (3) the ontogenetic pattern with 5-->6-->8-->12+ plates does not reflect Thoracica shell evolution; (4) the traditional asymmetric barnacles (Verrucidae) and the Balanomorpha......) the Thoracica suborders evolved since the Early Carboniferous (340mya) with the final radiation of the Sessilia in the Upper Jurassic (147mya). These results, therefore, reject many of the underlying hypotheses about character evolution in the Cirripedia Thoracica, stimulate a variety of new thoughts...

Essays on nonlinear evolutionary game dynamics

NARCIS (Netherlands)

Ochea, M.I.

2010-01-01

Evolutionary game theory has been viewed as an evolutionary repair of rational actor game theory in the hope that a population of boundedly rational players may attain convergence to classic rational solutions, such as the Nash Equilibrium, via some learning or evolutionary process. In this thesis

Relationship Between Exercise Heart Rate and Music\\ud Tempo Preference

OpenAIRE

Karageorghis, C. I; Jones, Leighton; Low, D. C

2006-01-01

The present study examined the predicted positive and linear relationship (Iwanaga, 1995a, 1995b) between exercise heart rate and music tempo preference. Initially, 128 undergraduate students (M age = 20.0 years, SD = 0.9) were surveyed to establish their three favorite music artists. A separate experimental group of 29 undergraduates (M age = 20.3 years, SD = 1.2) selected the music of a single artist from the three highest-rated artists from the earlier survey. They reported their\\ud prefer...

音乐节拍速度变化的辨别优势认知研究%A Research on Superiority of Distinguishing Music Tempo Changes

Institute of Scientific and Technical Information of China (English)

欧阳明; 肖鑫; 戴志强

2012-01-01

Processing music rhythm and tempo is based on time perception, which contains the processing of time duration, time inter- val, rhythmic pattern and grouping. In the studies of time duration, scientist found an interesting phenomenon called Time Order Error (Woodrow, 1951 ; Allan & Gibbon, 1994; Schab & Crowder, 1988), which claims that people have some biases on distinguishing the duration when it is less than 500ms or more than 700ms. And when the time duration is between 500ms and 700ms, there is no percep- tible difference. Later, some researchers found a similar phenomenon in the studies of time interval - - when the time interval is less than 500ms, people will estimate accelerated tempo changes more accurately. At a time interval more than 700ms, people will estimate slowdown tempo changes more accurately. When the time interval is between 500ms and 700ms, various investigations indicated differ- ent views on this issue. This work aimed to investigate whether people have perceptual bias when the time interval is 600ms (tempo lO0bpm). 600ms is considered to be the most natural interval in music (Fraisse, 1982; Krumhansl, 2000). But few experiments are based on this interval. In addition, there is no relevant study on the issue whether meter types ( such as duple and triple meter) will af- fect people~ judgment on the beat ahead or behind. So this paper also attempted to explore the impact of tempo changes by certain fac- tors such as change variety, change direction, and meter type, as well as different music learning background. This experiment chose two drum beats as downbeat and upbeat to perform duple and triple meter sequences. In each trail, there were three standard bars before the variable beat. The variable beat was put ahead or delayed for 15%, 10%, 8%, 5%, 2%, or ar- rived on time. The participants, who were music and non - music - major college students, were divided into two groups, according to whether he or she had more than 10 years of music

Integrating genomics into evolutionary medicine.

Science.gov (United States)

Rodríguez, Juan Antonio; Marigorta, Urko M; Navarro, Arcadi

2014-12-01

The application of the principles of evolutionary biology into medicine was suggested long ago and is already providing insight into the ultimate causes of disease. However, a full systematic integration of medical genomics and evolutionary medicine is still missing. Here, we briefly review some cases where the combination of the two fields has proven profitable and highlight two of the main issues hindering the development of evolutionary genomic medicine as a mature field, namely the dissociation between fitness and health and the still considerable difficulties in predicting phenotypes from genotypes. We use publicly available data to illustrate both problems and conclude that new approaches are needed for evolutionary genomic medicine to overcome these obstacles. Copyright © 2014 Elsevier Ltd. All rights reserved.

Form of an evolutionary tradeoff affects eco-evolutionary dynamics in a predator-prey system.

Science.gov (United States)

Kasada, Minoru; Yamamichi, Masato; Yoshida, Takehito

2014-11-11

Evolution on a time scale similar to ecological dynamics has been increasingly recognized for the last three decades. Selection mediated by ecological interactions can change heritable phenotypic variation (i.e., evolution), and evolution of traits, in turn, can affect ecological interactions. Hence, ecological and evolutionary dynamics can be tightly linked and important to predict future dynamics, but our understanding of eco-evolutionary dynamics is still in its infancy and there is a significant gap between theoretical predictions and empirical tests. Empirical studies have demonstrated that the presence of genetic variation can dramatically change ecological dynamics, whereas theoretical studies predict that eco-evolutionary dynamics depend on the details of the genetic variation, such as the form of a tradeoff among genotypes, which can be more important than the presence or absence of the genetic variation. Using a predator-prey (rotifer-algal) experimental system in laboratory microcosms, we studied how different forms of a tradeoff between prey defense and growth affect eco-evolutionary dynamics. Our experimental results show for the first time to our knowledge that different forms of the tradeoff produce remarkably divergent eco-evolutionary dynamics, including near fixation, near extinction, and coexistence of algal genotypes, with quantitatively different population dynamics. A mathematical model, parameterized from completely independent experiments, explains the observed dynamics. The results suggest that knowing the details of heritable trait variation and covariation within a population is essential for understanding how evolution and ecology will interact and what form of eco-evolutionary dynamics will result.

Practical advantages of evolutionary computation

Science.gov (United States)

Fogel, David B.

1997-10-01

Evolutionary computation is becoming a common technique for solving difficult, real-world problems in industry, medicine, and defense. This paper reviews some of the practical advantages to using evolutionary algorithms as compared with classic methods of optimization or artificial intelligence. Specific advantages include the flexibility of the procedures, as well as their ability to self-adapt the search for optimum solutions on the fly. As desktop computers increase in speed, the application of evolutionary algorithms will become routine.

BREVES CONSIDERAÇÕES SOBRE A ABORDAGEM DE CHARLES GUIGNON DO MÉTODO FENOMENOLÓGICO EM SER E TEMPO

Directory of Open Access Journals (Sweden)

Rogério Tolfo

2011-05-01

Full Text Available Este artigo apresenta os estágios do método filosófico em Ser e Tempo, deacordo com a obra Heidegger e o Problema do Conhecimento de Charles Guignon.Segundo Guignon, Heidegger realiza em Ser e Tempo um processo em etapas: 1.Descritivo; 2. Hermenêutico; 3. Processo Dialético; 4. Diagnóstico do Senso Comum. Oobjetivo principal deste artigo é divulgar a proposta de Guignon. No entanto, faremosbreves considerações sobre esta proposta.

A psicologia social nos tempos de S. Freud

Directory of Open Access Journals (Sweden)

Gustavo Adolfo Ramos Mello Neto

Full Text Available Trata-se de uma revisão dos textos psicossociais citados por Freud em Psicologia de massas e análise do eu. O objetivo é propor ao leitor algum conhecimento desses textos que já se perdem no tempo. São referidos textos de Wilfred Trotter, William MacDougall, Gustave Le Bon e Gabriel Tarde. Alude-se também a Durkheim, autor não citado por Freud, mas cuja referência permite contrastar uma visão psicologizante do fenômeno social, que é a de Freud e dos autores que ele cita, com um aporte em que o social é visto como independente do psicológico.

A psicologia social nos tempos de S. Freud

Directory of Open Access Journals (Sweden)

Mello Neto Gustavo Adolfo Ramos

2000-01-01

Full Text Available Trata-se de uma revisão dos textos psicossociais citados por Freud em Psicologia de massas e análise do eu. O objetivo é propor ao leitor algum conhecimento desses textos que já se perdem no tempo. São referidos textos de Wilfred Trotter, William MacDougall, Gustave Le Bon e Gabriel Tarde. Alude-se também a Durkheim, autor não citado por Freud, mas cuja referência permite contrastar uma visão psicologizante do fenômeno social, que é a de Freud e dos autores que ele cita, com um aporte em que o social é visto como independente do psicológico.

TEMPO functionalized C{sub 60} fullerene deposited on gold surface for catalytic oxidation of selected alcohols

Energy Technology Data Exchange (ETDEWEB)

Piotrowski, Piotr; Pawłowska, Joanna [University of Warsaw, Department of Chemistry (Poland); Sadło, Jarosław Grzegorz [Institute of Nuclear Chemistry and Technology (Poland); Bilewicz, Renata; Kaim, Andrzej, E-mail: akaim@chem.uw.edu.pl [University of Warsaw, Department of Chemistry (Poland)

2017-05-15

C{sub 60}TEMPO{sub 10} catalytic system linked to a microspherical gold support through a covalent S-Au bond was developed. The C{sub 60}TEMPO{sub 10}@Au composite catalyst had a particle size of 0.5–0.8 μm and was covered with the fullerenes derivative of 2.3 nm diameter bearing ten nitroxyl groups; the organic film showed up to 50 nm thickness. The catalytic composite allowed for the oxidation under mild conditions of various primary and secondary alcohols to the corresponding aldehyde and ketone analogues with efficiencies as high as 79–98%, thus giving values typical for homogeneous catalysis, while retaining at the same time all the advantages of heterogeneous catalysis, e.g., easy separation by filtration from the reaction mixture. The catalytic activity of the resulting system was studied by means of high pressure liquid chromatography. A redox mechanism was proposed for the process. In the catalytic cycle of the oxidation process, the TEMPO moiety was continuously regenerated in situ with an applied primary oxidant, for example, O{sub 2}/Fe{sup 3+} system. The new intermediate composite components and the final catalyst were characterized by various spectroscopic methods and thermogravimetry.

Nucleo multiprocessado para aplicações em tempo-real

OpenAIRE

Roberto Andre Hexsel

1988-01-01

Resumo: Esta Dissertação descreve o nucleo de tempo-real do Multiprocessador para Sistemas de Controle (MSC). O MSC foi desenvolvido no Instituto de Automação do Centro Tecnológico para Informática e possui características que o tornam adequado a aplicações em controle de processos e automação industrial. Estas aplicações exigem respostas rápidas a eventos externos e grande capacidade de processamento. O MSC pode ser configurado para satisfazer as mais diversas aplicações e diferentes níveis ...

Doença e Tempo

Directory of Open Access Journals (Sweden)

Fernando S. P. Telles

Full Text Available Trata-se de um ensaio que procura estabelecer a propriedade da questão: "Faz sentido conceber a doença como um fenômeno que transcende as categorias da representação?" Destaca-se uma correspondência entre os fenômenos da representação e da espacialização. Representar passa a ser a atividade de definir uma trajetória que admite uma cronologia temporal de referência, onde um certo fenômeno é apresentado. O paradigma que define a "Anátomo-Clínica" e a Epidemiologia é considerado por nós como uma forma de representação ou espacialização da doença. Conclui-se ser possível o acesso a algo que se denomina "adoecer", que transcende a representação "Anátomo-Clínica" e epidemiológica, desde que, para tal, se admita a possibilidade de o conhecimento poder ser, também, construído fora do espaço, isto é, no tempo não-cronológico.

EEG alpha desynchronization in musicians and nonmusicians in response to changes in melody, tempo, and key in classical music.

Science.gov (United States)

Overman, Amy A; Hoge, Jessica; Dale, J Alexander; Cross, Jeffrey D; Chien, Alec

2003-10-01

Two experiments were performed to examine musicians' and nonmusicians' electroencephalographic (EEG) responses to changes in major dimensions (tempo, melody, and key) of classical music. In Exp. 1, 12 nonmusicians' and 12 musicians' EEGs during melody and tempo changes in classical music showed more alpha desynchronization in the left hemisphere (F3) for changes in tempo than in the right. For melody, the nonmusicians were more right-sided (F4) than left in activation, and musicians showed no left-right differences. In Exp. 2, 18 musicians' and 18 nonmusicians' EEG after a key change in classical music showed that distant key changes elicited more right frontal (F4) alpha desynchronization than left. Musicians showed more reaction to key changes than nonmusicians and instructions to attend to key changes had no significant effect. Classical music, given its well-defined structure, offers a unique set of stimuli to study the brain. Results support the concept of hierarchical modularity in music processing that may be automatic.

Calculating evolutionary dynamics in structured populations.

Directory of Open Access Journals (Sweden)

Charles G Nathanson

2009-12-01

Full Text Available Evolution is shaping the world around us. At the core of every evolutionary process is a population of reproducing individuals. The outcome of an evolutionary process depends on population structure. Here we provide a general formula for calculating evolutionary dynamics in a wide class of structured populations. This class includes the recently introduced "games in phenotype space" and "evolutionary set theory." There can be local interactions for determining the relative fitness of individuals, but we require global updating, which means all individuals compete uniformly for reproduction. We study the competition of two strategies in the context of an evolutionary game and determine which strategy is favored in the limit of weak selection. We derive an intuitive formula for the structure coefficient, sigma, and provide a method for efficient numerical calculation.

Evolutionary Multiplayer Games

OpenAIRE

Gokhale, Chaitanya S.; Traulsen, Arne

2014-01-01

Evolutionary game theory has become one of the most diverse and far reaching theories in biology. Applications of this theory range from cell dynamics to social evolution. However, many applications make it clear that inherent non-linearities of natural systems need to be taken into account. One way of introducing such non-linearities into evolutionary games is by the inclusion of multiple players. An example is of social dilemmas, where group benefits could e.g.\\ increase less than linear wi...

Effects of Movement, Tempo, and Gender on Steady Beat Performance of Kindergarten Children

Science.gov (United States)

Rose, Paige

2016-01-01

The purposes of this research were to discover the effects of manual (hand) and pedal (foot) movements, tempo, and gender on steady beat accuracy. Participants (N = 119) consisted of male (n = 63) and female (n = 56) kindergarten students randomly divided into two groups, counterbalanced with regard to school, homeroom, and gender. Participants…

Asymmetric Evolutionary Games

Science.gov (United States)

McAvoy, Alex; Hauert, Christoph

2015-01-01

Evolutionary game theory is a powerful framework for studying evolution in populations of interacting individuals. A common assumption in evolutionary game theory is that interactions are symmetric, which means that the players are distinguished by only their strategies. In nature, however, the microscopic interactions between players are nearly always asymmetric due to environmental effects, differing baseline characteristics, and other possible sources of heterogeneity. To model these phenomena, we introduce into evolutionary game theory two broad classes of asymmetric interactions: ecological and genotypic. Ecological asymmetry results from variation in the environments of the players, while genotypic asymmetry is a consequence of the players having differing baseline genotypes. We develop a theory of these forms of asymmetry for games in structured populations and use the classical social dilemmas, the Prisoner’s Dilemma and the Snowdrift Game, for illustrations. Interestingly, asymmetric games reveal essential differences between models of genetic evolution based on reproduction and models of cultural evolution based on imitation that are not apparent in symmetric games. PMID:26308326

Efficacy of rasagiline in early Parkinson's disease: a meta-analysis of data from the TEMPO and ADAGIO studies.

Science.gov (United States)

Hauser, Robert A; Abler, Victor; Eyal, Eli; Eliaz, Rom E

2016-10-01

To evaluate the efficacy of rasagiline versus placebo in a pooled population of patients with early Parkinson's disease (PD). TEMPO and ADAGIO were Phase III studies that evaluated the symptomatic efficacy of rasagiline versus placebo in patients with early PD. This meta-analysis included Unified Parkinson's Disease Rating Scale (UPDRS) observations from weeks 12, 24 and 36 in ADAGIO and from weeks 14 and 26 in TEMPO; TEMPO visits were recoded to weeks 12 and 24, respectively. The present analysis includes all patients who received rasagiline 1 mg/day, 2 mg/day or placebo, and had ≥1 post-baseline observations and a subgroup of patients whose baseline UPDRS Total scores were ≥27 (Upper Quartile population). Change from baseline in UPDRS scores were evaluated using mixed models repeated measures analyses. Of the 1578 patients randomized to the two studies, 1546 patients met criteria for inclusion in the meta-analysis. Effects on UPDRS Total, motor and activities of daily living scores were significantly better for both doses of rasagiline compared with placebo at all time periods. The Upper Quartile population included 402 patients with a UPDRS Total score ≥27 at baseline. These patients generally demonstrated a larger magnitude of treatment effect than was seen in the full population. This meta-analysis confirms the efficacy of rasagiline monotherapy over 36 weeks. Although TEMPO and ADAGIO are considered studies of "very early" PD, both contained a sizeable pool of patients with more severe disease. In addition, the meta-analysis showed a larger magnitude of effect in patients with more severe baseline disease.

Avaliação do impacto da transferência precoce de informação no tempo e no custo de desenvolvimento de projetos

OpenAIRE

Daniel Drumond Campos e Silva

2010-01-01

O tempo de desenvolvimento de projetos é um fator de vantagem competitiva para as empresas responderem de forma rápida às exigências do mercado. A pressão pela agilização no repasse de informação entre tarefas, visando diminuir o tempo de projeto, pode impactar em retrabalho, considerando que esse repasse apresenta uma carga de incerteza quanto à assertividade do dado. Torna-se pertinente uma análise comparativa entre o tempo de finalização de um projeto e o custo associado a sua execução, co...

Industrial Applications of Evolutionary Algorithms

CERN Document Server

Sanchez, Ernesto; Tonda, Alberto

2012-01-01

This book is intended as a reference both for experienced users of evolutionary algorithms and for researchers that are beginning to approach these fascinating optimization techniques. Experienced users will find interesting details of real-world problems, and advice on solving issues related to fitness computation, modeling and setting appropriate parameters to reach optimal solutions. Beginners will find a thorough introduction to evolutionary computation, and a complete presentation of all evolutionary algorithms exploited to solve different problems. The book could fill the gap between the

Core principles of evolutionary medicine: A Delphi study.

Science.gov (United States)

Grunspan, Daniel Z; Nesse, Randolph M; Barnes, M Elizabeth; Brownell, Sara E

2018-01-01

Evolutionary medicine is a rapidly growing field that uses the principles of evolutionary biology to better understand, prevent and treat disease, and that uses studies of disease to advance basic knowledge in evolutionary biology. Over-arching principles of evolutionary medicine have been described in publications, but our study is the first to systematically elicit core principles from a diverse panel of experts in evolutionary medicine. These principles should be useful to advance recent recommendations made by The Association of American Medical Colleges and the Howard Hughes Medical Institute to make evolutionary thinking a core competency for pre-medical education. The Delphi method was used to elicit and validate a list of core principles for evolutionary medicine. The study included four surveys administered in sequence to 56 expert panelists. The initial open-ended survey created a list of possible core principles; the three subsequent surveys winnowed the list and assessed the accuracy and importance of each principle. Fourteen core principles elicited at least 80% of the panelists to agree or strongly agree that they were important core principles for evolutionary medicine. These principles over-lapped with concepts discussed in other articles discussing key concepts in evolutionary medicine. This set of core principles will be helpful for researchers and instructors in evolutionary medicine. We recommend that evolutionary medicine instructors use the list of core principles to construct learning goals. Evolutionary medicine is a young field, so this list of core principles will likely change as the field develops further.

Conceptual Barriers to Progress Within Evolutionary Biology.

Science.gov (United States)

Laland, Kevin N; Odling-Smee, John; Feldman, Marcus W; Kendal, Jeremy

2009-08-01

In spite of its success, Neo-Darwinism is faced with major conceptual barriers to further progress, deriving directly from its metaphysical foundations. Most importantly, neo-Darwinism fails to recognize a fundamental cause of evolutionary change, "niche construction". This failure restricts the generality of evolutionary theory, and introduces inaccuracies. It also hinders the integration of evolutionary biology with neighbouring disciplines, including ecosystem ecology, developmental biology, and the human sciences. Ecology is forced to become a divided discipline, developmental biology is stubbornly difficult to reconcile with evolutionary theory, and the majority of biologists and social scientists are still unhappy with evolutionary accounts of human behaviour. The incorporation of niche construction as both a cause and a product of evolution removes these disciplinary boundaries while greatly generalizing the explanatory power of evolutionary theory.

Evolutionary Statistical Procedures

CERN Document Server

Baragona, Roberto; Poli, Irene

2011-01-01

This proposed text appears to be a good introduction to evolutionary computation for use in applied statistics research. The authors draw from a vast base of knowledge about the current literature in both the design of evolutionary algorithms and statistical techniques. Modern statistical research is on the threshold of solving increasingly complex problems in high dimensions, and the generalization of its methodology to parameters whose estimators do not follow mathematically simple distributions is underway. Many of these challenges involve optimizing functions for which analytic solutions a

Qualidade fisiológica de sementes de camomila [Chamomilla recutita (L. Rauschert] após envelhecimento acelerado e estresse salino Physiological quality of chamomile [Chamomilla recutita (L. Rauschert] seeds after accelerated aging and salt stress

Directory of Open Access Journals (Sweden)

D.G Rollwagen

2011-01-01

Full Text Available O objetivo do trabalho foi verificar a qualidade fisiológica de sementes da camomila submetidas a diferentes tempos de envelhecimento acelerado e ao estresse salino. Os experimentos foram realizados no Laboratório de Técnica de Sementes na PUCPR em São José dos Pinhais, Paraná. Os tempos de envelhecimento acelerado foram de 0, 24, 48, 72 e 96 h e o estresse salino foi induzido por soluções de cloreto de sódio com potenciais osmóticos de 0; -0,2; -0,4; -0,6; -0,8; -1,0 MPa, ambos com quatro repetições. Foram avaliados a germinação, o índice de velocidade de germinação (IVG, o tempo médio de germinação (TMG, a velocidade media de germinação (VMG e a entropia. O delineamento experimental adotado foi o de blocos casualizados . Concluiu-se que as sementes de camomila tiveram sua qualidade fisiológica afetada após 24h de envelhecimento acelerado e sob estresse salino causado por solução de potencial osmótico de -0,6 MPaThe aim of this study was to verify the physiological quality of chamomile seeds subjected to different accelerated aging periods and salt stress. The experiments were carried out in the Laboratory of Seed Technique, PUCPR, São José dos Pinhais, Paraná State, Brazil. The accelerated aging periods were 0, 24, 48, 72 and 96 h and the salt stress was induced by sodium chloride solutions with osmotic potentials of 0, -0.2, -0.4, -0.6, -0.8, -1.0 MPa, both with four replicates. The analyzed variables were: germination, germination velocity index (GVI, average germination time (AGT, average germination velocity (AGV and entropy. Experimental design was in randomized blocks. Chamomile seeds had their physiological quality affected after 24 h of accelerated aging and under salt stress caused by the solution with osmotic potential of -0.6 MPa

Part E: Evolutionary Computation

DEFF Research Database (Denmark)

2015-01-01

of Computational Intelligence. First, comprehensive surveys of genetic algorithms, genetic programming, evolution strategies, parallel evolutionary algorithms are presented, which are readable and constructive so that a large audience might find them useful and – to some extent – ready to use. Some more general...... kinds of evolutionary algorithms, have been prudently analyzed. This analysis was followed by a thorough analysis of various issues involved in stochastic local search algorithms. An interesting survey of various technological and industrial applications in mechanical engineering and design has been...... topics like the estimation of distribution algorithms, indicator-based selection, etc., are also discussed. An important problem, from a theoretical and practical point of view, of learning classifier systems is presented in depth. Multiobjective evolutionary algorithms, which constitute one of the most...

Contemporary issues in evolutionary biology

Indian Academy of Sciences (India)

These discussions included, among others, the possible consequences of nonDNA-based inheritance—epigenetics and cultural evolution, niche construction, and developmental mechanisms on our understanding of the evolutionary process, speciation, complexity in biology, and constructing a formal evolutionary theory.

Carmen Covito’s ‘Tempo parziale’ : Mothering and Work in Italy in a Nutshell

NARCIS (Netherlands)

Jansen, M.M.

2016-01-01

Carmen Covito’s short story ‘Tempo parziale’ (2009) [‘Part Time’] can be read as a comment on the peculiarities of female employment and defective social policies in contemporary Italy. Originally written in 2007 for the INAIL campaign Diritti senza rovesci [Rights without flip side] against

Tempo do conhecimento interativo: reflexões sobre a inteligência coletiva e o pensamento complexo

Directory of Open Access Journals (Sweden)

Angela Halen Claro Bembem

2014-06-01

Full Text Available A predominância das tecnologias da informação e comunicação na atualidade tem encaminhado a Ciência da Informação a diferentes contextos de tempo e espaço. O tempo do conhecimento interativo e o Espaço do saber trazem novas perspectivas quanto à concepção e o uso das tecnologias. Utilizando como procedimento metodológico a análise exploratória e descritiva, e tomando como referencial teórico consolidados autores da área, pretende-se discorrer sobre essas alterações e refletir como a Ciência da Informação tem se posicionado frente a esses desafios. Observou-se que o pensamento crítico torna-se alternativa para a compreensão das tecnologias longe de uma prerrogativa determinista.

Previsão de tempos de internamento num hospital português: aplicação da metodologia CRISP-DM

OpenAIRE

Laureano, R. M. S.; Caetano, N.; Cortez, P.

2014-01-01

Com base nos dados disponíveis num hospital português relativos aos processos de internamento, ocorridos no período de 2000 a 2013, e seguindo a metodologia de data mining CRISP-DM, obteve-se um modelo de previsão dos tempos de internamento baseado no algoritmo random forest que apresentou uma elevada qualidade, e superior à obtida com outras técnicas de data mining, e que permitiu identificar os atributos clínicos do paciente como os mais importantes para a explicação dos tempos de ...

Expert-guided evolutionary algorithm for layout design of complex space stations

Science.gov (United States)

Qian, Zhiqin; Bi, Zhuming; Cao, Qun; Ju, Weiguo; Teng, Hongfei; Zheng, Yang; Zheng, Siyu

2017-08-01

The layout of a space station should be designed in such a way that different equipment and instruments are placed for the station as a whole to achieve the best overall performance. The station layout design is a typical nondeterministic polynomial problem. In particular, how to manage the design complexity to achieve an acceptable solution within a reasonable timeframe poses a great challenge. In this article, a new evolutionary algorithm has been proposed to meet such a challenge. It is called as the expert-guided evolutionary algorithm with a tree-like structure decomposition (EGEA-TSD). Two innovations in EGEA-TSD are (i) to deal with the design complexity, the entire design space is divided into subspaces with a tree-like structure; it reduces the computation and facilitates experts' involvement in the solving process. (ii) A human-intervention interface is developed to allow experts' involvement in avoiding local optimums and accelerating convergence. To validate the proposed algorithm, the layout design of one-space station is formulated as a multi-disciplinary design problem, the developed algorithm is programmed and executed, and the result is compared with those from other two algorithms; it has illustrated the superior performance of the proposed EGEA-TSD.

Research traditions and evolutionary explanations in medicine.

Science.gov (United States)

Méthot, Pierre-Olivier

2011-02-01

In this article, I argue that distinguishing 'evolutionary' from 'Darwinian' medicine will help us assess the variety of roles that evolutionary explanations can play in a number of medical contexts. Because the boundaries of evolutionary and Darwinian medicine overlap to some extent, however, they are best described as distinct 'research traditions' rather than as competing paradigms. But while evolutionary medicine does not stand out as a new scientific field of its own, Darwinian medicine is united by a number of distinctive theoretical and methodological claims. For example, evolutionary medicine and Darwinian medicine can be distinguished with respect to the styles of evolutionary explanations they employ. While the former primarily involves 'forward looking' explanations, the latter depends mostly on 'backward looking' explanations. A forward looking explanation tries to predict the effects of ongoing evolutionary processes on human health and disease in contemporary environments (e.g., hospitals). In contrast, a backward looking explanation typically applies evolutionary principles from the vantage point of humans' distant biological past in order to assess present states of health and disease. Both approaches, however, are concerned with the prevention and control of human diseases. In conclusion, I raise some concerns about the claim that 'nothing in medicine makes sense except in the light of evolution'.

Applications of evolutionary economic geography

NARCIS (Netherlands)

Boschma, R.A.; Frenken, K.; Puranam, Krishna Kishore; Ravi Kumar Jain B., xx

2008-01-01

This paper is written as the first chapter of an edited volume on evolutionary economics and economic geography (Frenken, K., editor, Applied Evolutionary Economics and Economic Geography, Cheltenham: Edward Elgar, expected publication date February 2007). The paper reviews empirical applications of

Programação de operações em sistemas com tempo de processamento variável

Directory of Open Access Journals (Sweden)

José Manuel Valério de Carvalho

2002-07-01

Full Text Available Neste artigo analisa-se um problema de planeamento de operações com tempos de processamento variável. Em particular, este projecto está relacionado com o planeamento de operações de carga de camiões em armazéns automáticos. As operações podem ser vistas como tarefas executadas em paralelo, com tempos de disponibilidade (data de chegada dos camiões e datas de entrega (data de cut off. Os tempos de processamento das tarefas são variáveis e dependem do número de tarefas a serem processadas simultaneamente; para garantir a taxa de expedição nominal de funcionamento do armazém, é necessário impor um número mínimo de tarefas em execução simultânea. Apresenta-se um procedimento baseado em programação dinâmica com os tempos de expedição dos camiões ordenados pela regra EDD. A eficiência do algoritmo é também discutida.In this work a scheduling operation problem with variable processing times is analysed. In particular this project is concerned with the scheduling of the truck load operations in an automatic warehouse. The truck load operations can be assumed as processing tasks in parallel, with ready times (availability of the trucks and due dates (trip cut off time. Processing time is variable and depends upon the number of tasks simultaneously in progress; a minimum number of simultaneous tasks is imposed to guarantee the nominal rate of expedition of the warehouse. A procedure based on Dynamic Programming with truck expedition times ordered by EDD rule is presented. The algorithm efficiency is also discussed.

Tempo 1 méthode de français

CERN Document Server

Bérard, Evelyne; Lavenne, Christian

1996-01-01

Tempo c'est : une méthode qui s'adresse aux adolescents et adultes, vrais débutants, des objectifs précis, définis par l'observation fine d'échanges authentiques, une progression rigoureuse où les acquis sont constamment repris et élargis, l'acquisition de compétences complètes dans un délai très bref (acquisitions par paliers), des techniques de classe dynamiques : apprentissage par tâches, une mise en scène active de la civilisation, de nombreux exercices, une évaluation régulière, une totale adéquation aux épreuves du DELF.

O tempo do luto e o discurso do Outro

OpenAIRE

Maesso, Márcia Cristina

2017-01-01

Resumo: Trata-se de uma leitura pelo método psicanalítico sobre o tempo de trabalho do luto, através do filme Sede de viver, da biografia de Van Gogh escrita por Forrester, e das concepções sobre o luto no campo da psicanálise, formuladas por Lacan e Allouch, visando abordar a travessia do luto como uma experiência que exige um trabalho não determinado exclusivamente pela relação entre o enlutado e o objeto perdido, mas contando com a função dos ritos e com a linguagem para concluir o luto co...

Evolutionary disarmament in interspecific competition.

Science.gov (United States)

Kisdi, E; Geritz, S A

2001-12-22

Competitive asymmetry, which is the advantage of having a larger body or stronger weaponry than a contestant, drives spectacular evolutionary arms races in intraspecific competition. Similar asymmetries are well documented in interspecific competition, yet they seldom lead to exaggerated traits. Here we demonstrate that two species with substantially different size may undergo parallel coevolution towards a smaller size under the same ecological conditions where a single species would exhibit an evolutionary arms race. We show that disarmament occurs for a wide range of parameters in an ecologically explicit model of competition for a single shared resource; disarmament also occurs in a simple Lotka-Volterra competition model. A key property of both models is the interplay between evolutionary dynamics and population density. The mechanism does not rely on very specific features of the model. Thus, evolutionary disarmament may be widespread and may help to explain the lack of interspecific arms races.

Recent advances in ambit stochastics with a view towards tempo-spatial stochastic volatility/intermittency

DEFF Research Database (Denmark)

Barndorff-Nielsen, Ole E.; Benth, Fred Espen; Veraart, Almut

Ambit stochastics is the name for the theory and applications of ambit fields and ambit processes and constitutes a new research area in stochastics for tempo-spatial phenomena. This paper gives an overview of the main findings in ambit stochastics up to date and establishes new results on genera...

Incorporating evolutionary principles into environmental management and policy

DEFF Research Database (Denmark)

Lankau, Richard; Jørgensen, Peter Søgaard; Harris, David J.

2011-01-01

As policymakers and managers work to mitigate the effects of rapid anthropogenic environmental changes, they need to consider organisms’ responses. In light of recent evidence that evolution can be quite rapid, this now includes evolutionary responses. Evolutionary principles have a long history...... in conservation biology, and the necessary next step for the field is to consider ways in which conservation policy makers and managers can proactively manipulate evolutionary processes to achieve their goals. In this review, we aim to illustrate the potential conservation benefits of an increased understanding...... of evolutionary history and prescriptive manipulation of three basic evolutionary factors: selection, variation, and gene flow. For each, we review and propose ways that policy makers and managers can use evolutionary thinking to preserve threatened species, combat pest species, or reduce undesirable evolutionary...

Efeito do tempo de conservação de polimorfonucleares do sangue de bezerros sobre o metabolismo oxidativo e a atividade de fagocitose de Escherichia coli

Directory of Open Access Journals (Sweden)

Elizabeth Bohland

2008-02-01

Full Text Available Foram avaliados os efeitos do tempo sobre o metabolismo oxidativo e a fagocitose de Escherichia coli, em amostras de polimorfonucleares (PMN do sangue, de cinco bezerros hígidos, conservadas em banho de gelo por duas (t2, quatro (t4, seis (t6, 12 (t12 e 24 (t24 horas. O metabolismo oxidativo foi avaliado utilizando o Diacetato 2' 7' Diclorofluoresceína (DCFH-DA e a E. coli, como estímulo. Para a fagocitose a mesma bactéria foi utilizada. As amostras foram analisadas por citometria de fluxo. O metabolismo oxidativo basal dos PMN do sangue de bezerros foi maior nos tempos t4, t6 e t12, do que em t2 (p<0,05. A intensidade de fluorescência do metabolismo oxidativo induzido pela bactéria foi maior nos tempos t4 e t6 do que em t2 (p<0,05. A comparação entre o metabolismo basal e induzido pela bactéria, em cada um dos tempos, mostrou que a maior diferença ocorreu em t2, com valores da média geométrica e desvios padrão respectivos de 18,3 ± 4,4 e 26,7 ± 1,8 (p< 0,05. A atividade de fagocitose, medida pela intensidade de fluorescência, foi maior para as amostras mantidas em gelo por 6 horas do que para t2, t4 e t12 (p<0,05. O percentual de fagocitose não diferiu entre os tempos. O tempo ideal para análise do metabolismo oxidativo foi o de duas horas. Maiores estudos são necessários para se verificar a influência do tempo de conservação na fagocitose de E. coli por PMN do sangue de bovinos.

Evolutionary economics and industry location

NARCIS (Netherlands)

Boschma, R.A.; Frenken, K.

2003-01-01

This paper aims to provide the outlines of an evolutionary economic geography of industry location. We discuss two evolutionary explanations of industry location, that is, one that concentrates on spin-offs, and one that focuses attention on knowledge and agglomeration economies. We claim that both

Evolutionary institutionalism.

Science.gov (United States)

Fürstenberg, Dr Kai

Institutions are hard to define and hard to study. Long prominent in political science have been two theories: Rational Choice Institutionalism (RCI) and Historical Institutionalism (HI). Arising from the life sciences is now a third: Evolutionary Institutionalism (EI). Comparative strengths and weaknesses of these three theories warrant review, and the value-to-be-added by expanding the third beyond Darwinian evolutionary theory deserves consideration. Should evolutionary institutionalism expand to accommodate new understanding in ecology, such as might apply to the emergence of stability, and in genetics, such as might apply to political behavior? Core arguments are reviewed for each theory with more detailed exposition of the third, EI. Particular attention is paid to EI's gene-institution analogy; to variation, selection, and retention of institutional traits; to endogeneity and exogeneity; to agency and structure; and to ecosystem effects, institutional stability, and empirical limitations in behavioral genetics. RCI, HI, and EI are distinct but complementary. Institutional change, while amenable to rational-choice analysis and, retrospectively, to criticaljuncture and path-dependency analysis, is also, and importantly, ecological. Stability, like change, is an emergent property of institutions, which tend to stabilize after change in a manner analogous to allopatric speciation. EI is more than metaphorically biological in that institutional behaviors are driven by human behaviors whose evolution long preceded the appearance of institutions themselves.

Evolutionary foundations for cancer biology.

Science.gov (United States)

Aktipis, C Athena; Nesse, Randolph M

2013-01-01

New applications of evolutionary biology are transforming our understanding of cancer. The articles in this special issue provide many specific examples, such as microorganisms inducing cancers, the significance of within-tumor heterogeneity, and the possibility that lower dose chemotherapy may sometimes promote longer survival. Underlying these specific advances is a large-scale transformation, as cancer research incorporates evolutionary methods into its toolkit, and asks new evolutionary questions about why we are vulnerable to cancer. Evolution explains why cancer exists at all, how neoplasms grow, why cancer is remarkably rare, and why it occurs despite powerful cancer suppression mechanisms. Cancer exists because of somatic selection; mutations in somatic cells result in some dividing faster than others, in some cases generating neoplasms. Neoplasms grow, or do not, in complex cellular ecosystems. Cancer is relatively rare because of natural selection; our genomes were derived disproportionally from individuals with effective mechanisms for suppressing cancer. Cancer occurs nonetheless for the same six evolutionary reasons that explain why we remain vulnerable to other diseases. These four principles-cancers evolve by somatic selection, neoplasms grow in complex ecosystems, natural selection has shaped powerful cancer defenses, and the limitations of those defenses have evolutionary explanations-provide a foundation for understanding, preventing, and treating cancer.

Evolutionary principles and their practical application

DEFF Research Database (Denmark)

Hendry, A. P.; Kinnison, M. T.; Heino, M.

2011-01-01

Evolutionary principles are now routinely incorporated into medicine and agriculture. Examples include the design of treatments that slow the evolution of resistance by weeds, pests, and pathogens, and the design of breeding programs that maximize crop yield or quality. Evolutionary principles...... are also increasingly incorporated into conservation biology, natural resource management, and environmental science. Examples include the protection of small and isolated populations from inbreeding depression, the identification of key traits involved in adaptation to climate change, the design...... of harvesting regimes that minimize unwanted life-history evolution, and the setting of conservation priorities based on populations, species, or communities that harbor the greatest evolutionary diversity and potential. The adoption of evolutionary principles has proceeded somewhat independently...

Gender Inequality in Interaction--An Evolutionary Account

Science.gov (United States)

Hopcroft, Rosemary L.

2009-01-01

In this article I argue that evolutionary theorizing can help sociologists and feminists better understand gender inequality. Evolutionary theory explains why control of the sexuality of young women is a priority across most human societies both past and present. Evolutionary psychology has extended our understanding of male violence against…

Previsão de tempos de internamento num hospital português: aplicação da metodologia CRISP-DM

Directory of Open Access Journals (Sweden)

Raul M. S. Laureano

2014-06-01

Full Text Available Com base nos dados disponíveis num hospital português relativos aos processos de internamento, ocorridos no período de 2000 a 2013, e seguindo a metodologia de data mining CRISP-DM, obteve-se um modelo de previsão dos tempos de internamento baseado no algoritmo random forest que apresentou uma elevada qualidade, e superior à obtida com outras técnicas de data mining, e que permitiu identificar os atributos clínicos do paciente como os mais importantes para a explicação dos tempos de internamento

TEMPO-Oxidized Nanofibrillated Cellulose as a High Density Carrier for Bioactive Molecules.

Science.gov (United States)

Weishaupt, Ramon; Siqueira, Gilberto; Schubert, Mark; Tingaut, Philippe; Maniura-Weber, Katharina; Zimmermann, Tanja; Thöny-Meyer, Linda; Faccio, Greta; Ihssen, Julian

2015-11-09

Controlled and efficient immobilization of specific biomolecules is a key technology to introduce new, favorable functions to materials suitable for biomedical applications. Here, we describe an innovative and efficient, two-step methodology for the stable immobilization of various biomolecules, including small peptides and enzymes onto TEMPO oxidized nanofibrillated cellulose (TO-NFC). The introduction of carboxylate groups to NFC by TEMPO oxidation provided a high surface density of negative charges able to drive the adsorption of biomolecules and take part in covalent cross-linking reactions with 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDAC) and glutaraldehyde (Ga) chemistry. Up to 0.27 μmol of different biomolecules per mg of TO-NFC could be reversibly immobilized by electrostatic interaction. An additional chemical cross-linking step prevented desorption of more than 80% of these molecules. Using the cysteine-protease papain as model, a highly active papain-TO-NFC conjugate was achieved. Once papain was immobilized, 40% of the initial enzymatic activity was retained, with an increase in kcat from 213 to >700 s(-1) for the covalently immobilized enzymes. The methodology presented in this work expands the range of application for TO-NFC in the biomedical field by enabling well-defined hybrid biomaterials with a high density of functionalization.

Uudised : EFK ja TKO kontserdireis. Ajakiri Tempo Veljo Tormisest. Maestro Teo Maiste CD / Allan Vurma

Index Scriptorium Estoniae

Vurma, Allan, 1955-

2000-01-01

EFK ja TKO kontsertreisist USAsse ja Kanadasse 4.-23. veebr. Inglise kaasaegse muusika kvartalikiri "Tempo" jaanuarinumber (nr. 211) avaldas ulatusliku artikli V. Tormisest. 3. veebr. tähistati Estonia talveaias järjekordse CD ilmumist sarjas "Estonia väljapaistvaid lauljaid", peakangelaseks T. Maiste

Contemporary issues in evolutionary biology

Indian Academy of Sciences (India)

We are delighted to bring to the readers, a set of peer-reviewed papers on evolutionary biology, published as a special issue of the Journal of Genetics. These papers emanated from ruminations upon and discussions at the Foundations of. Evolutionary Theory: the Ongoing Synthesis meeting at Coorg, India, in February ...

PALIMPSESTOS DE CLIO ENTRE A CLEPSIDRA E O CLARIM: Comunicação, História Oral e Tempo Presente

OpenAIRE

Soares, Fagno da Silva; Rovai, Marta Gouveia de Oliveira; Porto Junior, Francisco Gilson Rebouças

2017-01-01

A Revista Observatório vem se estabelecendo como importante periódico interdisciplinar nacional, traz à baila seu Dossiê Volume 2, "Comunicação, História Oral e Tempo Presente", objetivando visibilizar trabalhos de diversos campos do conhecimento que perscrutam temáticas filigranadas na relação entre comunicação, história oral e tempo presente, bem como, suas ressonâncias historiográficas em face das sociedades do contemporâneo. Soma-se a isto, o intento de coadunar estudos aparentemente dí...

HALAMAN MUKA MAJALAH TEMPO (Studi Analisis isi Perbedaan Halaman Muka Sebagai Representasi Tajuk Utama Majalah Tempo Edisi Tahun 1993/1994 dengan Tahun 2009/2010

Directory of Open Access Journals (Sweden)

Lukman Nusa

2016-04-01

Full Text Available Abstrak Tidak ada yang lebih penting dari sebuah majalah selain halaman mukanya. Sebuah halaman muka menentukan pandangan pertama yang nantinya juga akan mempengaruhi minat baca dari khalayak. Bagi media cetak yang sadar akan arti pentingya, halaman muka didesain sedemikian rupa hingga menjadi sebuah desain sederhana namun kompetitif dan menarik sekaligus mencerminkan filosofi dari media tersebut. Selanjutnya, sebuah teori pendekatan lingkungan menyatakan bahwa sampai pada tingkat tertentu, sistem politik berpengaruh pada komunikasi begitupun sebaliknya. Teori semacam ini menjelaskan bahwa dengan kebijakan-kebijakan yang dilahirkan pada sebuah sistem politik, hingga tingkat tertentu berpengaruh pada pemberitaan sebuah media. Berdasarkan uraian tersebut, masalah yang diangkat dalam penelitian ini adalah bagaimana kecenderungan pemberitaan majalah berita nasional Tempo yang dapat dilihat dari bagian halaman mukanya pada dua periode yang memiliki karakteristik sistem politik yang berseberangan di Indonesia Kata kunci: Media, Politik, Konten Analisis. Abstract None of the magazine’s part which as important as its cover. The magazine covers determine the people’s first impression futhermore will influence their interest to read. For the press media who realize the importances, the covers will be designed as a simple but competitive and interesting design which representating the media’s philosophy. Futhermore, the theory of Environment states that until specific level, political system influences communication vise versa. This theory describes that the governement policy which is born in a political system, until a specific level, influences the news release. Base from the states, the problem of this research is the preference of Tempo the national news magazine’s news release which can be seen from its covers at two periods which has different political system’s characteristic in Indonesia. Keywords: Media, Politik, Content Analysis

Karyotypic changes through dysploidy persist longer over evolutionary time than polyploid changes.

Directory of Open Access Journals (Sweden)

Marcial Escudero

Full Text Available Chromosome evolution has been demonstrated to have profound effects on diversification rates and speciation in angiosperms. While polyploidy has predated some major radiations in plants, it has also been related to decreased diversification rates. There has been comparatively little attention to the evolutionary role of gains and losses of single chromosomes, which may or not entail changes in the DNA content (then called aneuploidy or dysploidy, respectively. In this study we investigate the role of chromosome number transitions and of possible associated genome size changes in angiosperm evolution. We model the tempo and mode of chromosome number evolution and its possible correlation with patterns of cladogenesis in 15 angiosperm clades. Inferred polyploid transitions are distributed more frequently towards recent times than single chromosome gains and losses. This is likely because the latter events do not entail changes in DNA content and are probably due to fission or fusion events (dysploidy, as revealed by an analysis of the relationship between genome size and chromosome number. Our results support the general pattern that recently originated polyploids fail to persist, and suggest that dysploidy may have comparatively longer-term persistence than polyploidy. Changes in chromosome number associated with dysploidy were typically observed across the phylogenies based on a chi-square analysis, consistent with these changes being neutral with respect to diversification.

Effects of Excerpt Tempo and Duration on Musicians' Ratings of High-Level Piano Performances

Science.gov (United States)

Wapnick, Joel; Ryan, Charlene; Campbell, Louise; Deek, Patricia; Lemire, Renata; Darrow, Alice-Ann

2005-01-01

The purpose of this study was to determine how judgments of solo performances recorded at an international piano competition might be affected by excerpt duration (20 versus 60 seconds) and tempo (slow versus fast). Musicians rated performances on six test items. Results indicated that piano majors rated slow excerpts higher than they rated fast…

Archaeogenetics in evolutionary medicine.

Science.gov (United States)

Bouwman, Abigail; Rühli, Frank

2016-09-01

Archaeogenetics is the study of exploration of ancient DNA (aDNA) of more than 70 years old. It is an important part of the wider studies of many different areas of our past, including animal, plant and pathogen evolution and domestication events. Hereby, we address specifically the impact of research in archaeogenetics in the broader field of evolutionary medicine. Studies on ancient hominid genomes help to understand even modern health patterns. Human genetic microevolution, e.g. related to abilities of post-weaning milk consumption, and specifically genetic adaptation in disease susceptibility, e.g. towards malaria and other infectious diseases, are of the upmost importance in contributions of archeogenetics on the evolutionary understanding of human health and disease. With the increase in both the understanding of modern medical genetics and the ability to deep sequence ancient genetic information, the field of archaeogenetic evolutionary medicine is blossoming.

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

Science.gov (United States)

Tamura, Koichiro; Peterson, Daniel; Peterson, Nicholas; Stecher, Glen; Nei, Masatoshi; Kumar, Sudhir

2011-01-01

Comparative analysis of molecular sequence data is essential for reconstructing the evolutionary histories of species and inferring the nature and extent of selective forces shaping the evolution of genes and species. Here, we announce the release of Molecular Evolutionary Genetics Analysis version 5 (MEGA5), which is a user-friendly software for mining online databases, building sequence alignments and phylogenetic trees, and using methods of evolutionary bioinformatics in basic biology, biomedicine, and evolution. The newest addition in MEGA5 is a collection of maximum likelihood (ML) analyses for inferring evolutionary trees, selecting best-fit substitution models (nucleotide or amino acid), inferring ancestral states and sequences (along with probabilities), and estimating evolutionary rates site-by-site. In computer simulation analyses, ML tree inference algorithms in MEGA5 compared favorably with other software packages in terms of computational efficiency and the accuracy of the estimates of phylogenetic trees, substitution parameters, and rate variation among sites. The MEGA user interface has now been enhanced to be activity driven to make it easier for the use of both beginners and experienced scientists. This version of MEGA is intended for the Windows platform, and it has been configured for effective use on Mac OS X and Linux desktops. It is available free of charge from http://www.megasoftware.net. PMID:21546353

Evolutionary relevance facilitates visual information processing.

Science.gov (United States)

Jackson, Russell E; Calvillo, Dusti P

2013-11-03

Visual search of the environment is a fundamental human behavior that perceptual load affects powerfully. Previously investigated means for overcoming the inhibitions of high perceptual load, however, generalize poorly to real-world human behavior. We hypothesized that humans would process evolutionarily relevant stimuli more efficiently than evolutionarily novel stimuli, and evolutionary relevance would mitigate the repercussions of high perceptual load during visual search. Animacy is a significant component to evolutionary relevance of visual stimuli because perceiving animate entities is time-sensitive in ways that pose significant evolutionary consequences. Participants completing a visual search task located evolutionarily relevant and animate objects fastest and with the least impact of high perceptual load. Evolutionarily novel and inanimate objects were located slowest and with the highest impact of perceptual load. Evolutionary relevance may importantly affect everyday visual information processing.

Mean-Potential Law in Evolutionary Games

Science.gov (United States)

Nałecz-Jawecki, Paweł; Miekisz, Jacek

2018-01-01

The Letter presents a novel way to connect random walks, stochastic differential equations, and evolutionary game theory. We introduce a new concept of a potential function for discrete-space stochastic systems. It is based on a correspondence between one-dimensional stochastic differential equations and random walks, which may be exact not only in the continuous limit but also in finite-state spaces. Our method is useful for computation of fixation probabilities in discrete stochastic dynamical systems with two absorbing states. We apply it to evolutionary games, formulating two simple and intuitive criteria for evolutionary stability of pure Nash equilibria in finite populations. In particular, we show that the 1 /3 law of evolutionary games, introduced by Nowak et al. [Nature, 2004], follows from a more general mean-potential law.

Is evolutionary psychology a metatheory for psychology? A discussion of four major issues in psychology from an evolutionary developmental perspective

NARCIS (Netherlands)

Ploeger, A.; van der Maas, H.L.J.; Raijmakers, M.E.J.

2008-01-01

Evolutionary psychology has been proposed as a metatheoretical framework for psychology. We argue that evolutionary psychology should be expanded if it is to offer new insights regarding the major issues in psychology. Evolutionary developmental biology can provide valuable new insights into issues

Characteristics of a free-standing film from banana pseudostem nanocellulose generated from TEMPO-mediated oxidation.

Science.gov (United States)

Faradilla, R H Fitri; Lee, George; Arns, Ji-Youn; Roberts, Justine; Martens, Penny; Stenzel, Martina H; Arcot, Jayashree

2017-10-15

Demand for bioplastic, especially for food packaging, increases as the consumers become more aware of the destructive effect of non-biodegradable plastics. Nanocellulose from banana pseudo-stem has great potential to be formed as a bioplastic. This study aimed to characterize the free-standing film produced from banana pseudo-stem nanocellulose that was prepared by TEMPO-mediated oxidation. The film was found containing calcium oxalate crystals, which most likely influenced the film transparency and possibly affected the contact angle and tensile strength. The film had initial degradation temperature at 205°C, the contact angle of 64.3°, the tensile strength of 59.5MPa, and elongation of 1.7%. This initial characterization of free-standing nanocellulose film showed a promising potential of TEMPO-treated nanocellulose from banana pseudo-stem as a source of bioplastic. This study could also be beneficial information for further possible modification to improve the banana pseudo-stem film properties. Copyright © 2017 Elsevier Ltd. All rights reserved.

Evolutionary conservation and changes in insect TRP channels.

Science.gov (United States)

Matsuura, Hironori; Sokabe, Takaaki; Kohno, Keigo; Tominaga, Makoto; Kadowaki, Tatsuhiko

2009-09-10

may suggest that single TRP channels are responsible for integrating diverse sensory inputs to maintain the insect sensory systems. The above results demonstrate that there are both evolutionary conservation and changes in insect TRP channels. In particular, the evolutionary processes have been accelerated in the TRPA subfamily, indicating divergence in the mechanisms that insects use to detect environmental temperatures.

Evolutionary conservation and changes in insect TRP channels

Directory of Open Access Journals (Sweden)

Tominaga Makoto

2009-09-01

family members. As shown for mammalian TRP channels, this may suggest that single TRP channels are responsible for integrating diverse sensory inputs to maintain the insect sensory systems. The above results demonstrate that there are both evolutionary conservation and changes in insect TRP channels. In particular, the evolutionary processes have been accelerated in the TRPA subfamily, indicating divergence in the mechanisms that insects use to detect environmental temperatures.

Comparison of evolutionary computation algorithms for solving bi ...

Indian Academy of Sciences (India)

failure probability. Multiobjective Evolutionary Computation algorithms (MOEAs) are well-suited for Multiobjective task scheduling on heterogeneous environment. The two Multi-Objective Evolutionary Algorithms such as Multiobjective Genetic. Algorithm (MOGA) and Multiobjective Evolutionary Programming (MOEP) with.

Species co-evolutionary algorithm: a novel evolutionary algorithm based on the ecology and environments for optimization

DEFF Research Database (Denmark)

Li, Wuzhao; Wang, Lei; Cai, Xingjuan

2015-01-01

and affect each other in many ways. The relationships include competition, predation, parasitism, mutualism and pythogenesis. In this paper, we consider the five relationships between solutions to propose a co-evolutionary algorithm termed species co-evolutionary algorithm (SCEA). In SCEA, five operators...

Velocities and joint angles during double backward stretched salto performed with stable landing and in combination with tempo salto

Directory of Open Access Journals (Sweden)

J Sadowski

2009-07-01

Full Text Available The aim of the study was to compare the values of velocity an joint angles obtained during performance of double salto backward stretched with a stable landing and its combination with salto tempo. Seven top level acrobats (track jumpers participated in study. Mean values of body height, mass and age had a value of: 170 cm ± 4.0 cm, 72.4 kg ± 3.6 kg, 20.4±1.7 years, respectively. The studies were conducted on a standard acrobatic path (type PTS 2000. Two digital video cameras (240 Hz and APAS 2000 (Ariel Dynamics Inc. were used during studies. Markers were placed in ankle, knee, hip, arm, elbow and wrist joints. All marker positions were tracked and reconstructed using the APAS system. Two sequences with the following elements were analysed: round-off - double salto backward stretched (A and round-off - double salto backward stretched - tempo salto (B. The highest differences between the key components describing performance of presented exercises exist for joint angles during launching and landing position, and resultant velocities during touchdown. In version A the athlete created prerequisites for “gliding” double salto backward stretched by means of the body segments motions, whereas in version B he executes faster motions of the body segments accentuating his actions upon backward rotation of the body. During the final phase of double salto backward stretched in combination with tempo salto the athlete performed courbette “under himself” (almost straight feet are placed in front of vertical line, pushes directly back and in 0,1 s executes stable arm swing upward-backward to tempo salto.

Fixation Time for Evolutionary Graphs

Science.gov (United States)

Nie, Pu-Yan; Zhang, Pei-Ai

Evolutionary graph theory (EGT) is recently proposed by Lieberman et al. in 2005. EGT is successful for explaining biological evolution and some social phenomena. It is extremely important to consider the time of fixation for EGT in many practical problems, including evolutionary theory and the evolution of cooperation. This study characterizes the time to asymptotically reach fixation.

PERSONAL BRANDING PRABOWO SUBIANTO (ANALISIS ISI KUANTITATIF PERSONAL BRANDING PRABOWO SUBIANTO DI SITUS BERITA ONLINE REPUBLIKA.CO.ID DAN TEMPO.CO.ID TANGGAL 9 JUNI - 9 JULI 2014

Directory of Open Access Journals (Sweden)

Hendro Agus Prakoso

2016-09-01

berita kedua media tersebut. Frekuensi berita berjumlah 107 di Republika.co.id dan 51 berita di Tempo.co.id Ragam berita Republika.co.id didominasi konsep Spesialisasi sebesar 22,4% dari 107 berita, sedangkan pada Tempo.co.id didominasi konsep Nama baik sebesar 23,5% dari 51 berita. Sumber berita pada Republika.co.id mayoritas berasal dari Liputan langsung sebesar 42,9% dari 107 berita sedangkan pada Tempo.co.id mayoritas berasal dari Intelektual sebesar 54,9% dari 51 berita.

Evolutionary computation in zoology and ecology.

Science.gov (United States)

Boone, Randall B

2017-12-01

Evolutionary computational methods have adopted attributes of natural selection and evolution to solve problems in computer science, engineering, and other fields. The method is growing in use in zoology and ecology. Evolutionary principles may be merged with an agent-based modeling perspective to have individual animals or other agents compete. Four main categories are discussed: genetic algorithms, evolutionary programming, genetic programming, and evolutionary strategies. In evolutionary computation, a population is represented in a way that allows for an objective function to be assessed that is relevant to the problem of interest. The poorest performing members are removed from the population, and remaining members reproduce and may be mutated. The fitness of the members is again assessed, and the cycle continues until a stopping condition is met. Case studies include optimizing: egg shape given different clutch sizes, mate selection, migration of wildebeest, birds, and elk, vulture foraging behavior, algal bloom prediction, and species richness given energy constraints. Other case studies simulate the evolution of species and a means to project shifts in species ranges in response to a changing climate that includes competition and phenotypic plasticity. This introduction concludes by citing other uses of evolutionary computation and a review of the flexibility of the methods. For example, representing species' niche spaces subject to selective pressure allows studies on cladistics, the taxon cycle, neutral versus niche paradigms, fundamental versus realized niches, community structure and order of colonization, invasiveness, and responses to a changing climate.

Evolutionary accounts of human behavioural diversity

Science.gov (United States)

Brown, Gillian R.; Dickins, Thomas E.; Sear, Rebecca; Laland, Kevin N.

2011-01-01

Human beings persist in an extraordinary range of ecological settings, in the process exhibiting enormous behavioural diversity, both within and between populations. People vary in their social, mating and parental behaviour and have diverse and elaborate beliefs, traditions, norms and institutions. The aim of this theme issue is to ask whether, and how, evolutionary theory can help us to understand this diversity. In this introductory article, we provide a background to the debate surrounding how best to understand behavioural diversity using evolutionary models of human behaviour. In particular, we examine how diversity has been viewed by the main subdisciplines within the human evolutionary behavioural sciences, focusing in particular on the human behavioural ecology, evolutionary psychology and cultural evolution approaches. In addition to differences in focus and methodology, these subdisciplines have traditionally varied in the emphasis placed on human universals, ecological factors and socially learned behaviour, and on how they have addressed the issue of genetic variation. We reaffirm that evolutionary theory provides an essential framework for understanding behavioural diversity within and between human populations, but argue that greater integration between the subfields is critical to developing a satisfactory understanding of diversity. PMID:21199836

The tempo-spatially modulated polarization atmosphere Michelson interferometer.

Science.gov (United States)

Zhang, ChunMin; Zhu, HuaChun; Zhao, Baochang

2011-05-09

A space-based tempo-spatially modulated polarization atmosphere Michelson interferometer (TSMPAMI) is described. It uses the relative movement between the TSMPAMI and the measured target to change optical path difference. The acquisition method of interferogram is presented. The atmospheric temperatures and horizontal winds can be derived from the optical observations. The measurement errors of the winds and temperatures are discussed through simulations. In the presence of small-scale structures of the atmospheric fields, the errors are found to be significantly influenced by the mismatch of the scenes observed by the adjacent CCD sub-areas aligned along the orbiter's track during successive measurements due to the orbital velocity and the exposure time. For most realistic conditions of the orbit and atmosphere, however, the instrument is proven suitable for measuring the atmospheric parameters. © 2011 Optical Society of America

Evolutionary Relevance Facilitates Visual Information Processing

Directory of Open Access Journals (Sweden)

Russell E. Jackson

2013-07-01

Full Text Available Visual search of the environment is a fundamental human behavior that perceptual load affects powerfully. Previously investigated means for overcoming the inhibitions of high perceptual load, however, generalize poorly to real-world human behavior. We hypothesized that humans would process evolutionarily relevant stimuli more efficiently than evolutionarily novel stimuli, and evolutionary relevance would mitigate the repercussions of high perceptual load during visual search. Animacy is a significant component to evolutionary relevance of visual stimuli because perceiving animate entities is time-sensitive in ways that pose significant evolutionary consequences. Participants completing a visual search task located evolutionarily relevant and animate objects fastest and with the least impact of high perceptual load. Evolutionarily novel and inanimate objects were located slowest and with the highest impact of perceptual load. Evolutionary relevance may importantly affect everyday visual information processing.

Evolutionary games on graphs

Science.gov (United States)

Szabó, György; Fáth, Gábor

2007-07-01

Game theory is one of the key paradigms behind many scientific disciplines from biology to behavioral sciences to economics. In its evolutionary form and especially when the interacting agents are linked in a specific social network the underlying solution concepts and methods are very similar to those applied in non-equilibrium statistical physics. This review gives a tutorial-type overview of the field for physicists. The first four sections introduce the necessary background in classical and evolutionary game theory from the basic definitions to the most important results. The fifth section surveys the topological complications implied by non-mean-field-type social network structures in general. The next three sections discuss in detail the dynamic behavior of three prominent classes of models: the Prisoner's Dilemma, the Rock-Scissors-Paper game, and Competing Associations. The major theme of the review is in what sense and how the graph structure of interactions can modify and enrich the picture of long term behavioral patterns emerging in evolutionary games.

A Note on Evolutionary Algorithms and Its Applications

Science.gov (United States)

Bhargava, Shifali

2013-01-01

This paper introduces evolutionary algorithms with its applications in multi-objective optimization. Here elitist and non-elitist multiobjective evolutionary algorithms are discussed with their advantages and disadvantages. We also discuss constrained multiobjective evolutionary algorithms and their applications in various areas.

“Venha o teu reino”: representações do tempo na Igreja Evangélica Assembléia de Deus do Brasil (1995-2005.

Directory of Open Access Journals (Sweden)

Vinicius Emanuel Rodrigues

2012-08-01

Full Text Available Este trabalho desenvolve uma análise sobre as representações do tempo na maior igreja evangélica pentecostal do Brasil, a Igreja Evangélica Assembleia de Deus (fundada em 1911, entre os anos 1995 e 2005. Fundamentados no pensamento teórico de Roger Chartier, Norbert Elias e Mircea Eliade discorremos sobre como essa igreja sofre influências do modelo linear de tempo do cristianismo, assim como realiza releituras do tempo secular inserindo-o no tempo sagrado a partir de sua cosmovisão escatológica. O período escolhido para análise também manifesta o pensamento da igreja sobre um elemento muito presente nas sociedades ocidentais das viradas de século e de milênio, o “milenarismo”. Para tanto, nos utilizamos de fontes muito pertinentes para a compreensão desses elementos, trata-se do principal órgão de doutrinação da instituição, a revista Lições Bíblicas, e de seu jornal oficial, o Mensageiro da Paz, ambos hegemônicos em seus segmentos e, portanto, reveladores do discurso oficial da referida igreja.

Investigação de perdas devido ao trabalho inacabado e o seu impacto no tempo de ciclo dos processos construtivos

Directory of Open Access Journals (Sweden)

Paulo Ricardo Ramos Santos

Full Text Available Resumo As perdas na construção civil constituem um entrave à melhoria da produtividade. Dentre os diversos tipos de perdas, o making-do se destaca por representar uma fonte de outras perdas. Fireman et al. (2013, ao estudarem o making-do, concluíram que ele pode ser desencadeado por um tipo de perda geral, denominada de trabalho inacabado. O objetivo do presente trabalho foi investigar a ocorrência do trabalho inacabado nos processos construtivos e o seu impacto no tempo de ciclo dos serviços. A pesquisa foi de um levantamento de campo em cinco canteiros, envolvendo observação direta. Utilizou-se como ferramentas de pesquisa: formulário, questionários e checklist, adaptados da literatura para identificação e classificação do trabalho inacabado, bem como aferição do seu impacto no tempo de ciclo. Houve também entrevistas não estruturadas com os gerentes de obras, mestres e encarregados. Os resultados mostraram que as falhas no sequenciamento das tarefas associadas com falhas na gestão da qualidade serviram de desencadeadores para o trabalho inacabado. Notou-se que os canteiros que apresentaram planos de curto prazo formalizados atenuaram os impactos desse tipo de perda. Na maioria das obras o tempo de ciclo previsto não foi cumprido, observando-se que aquelas que tinham equipe administrativa mais encorpada obtiveram acréscimo de tempo menor.

O espaço social e o tempo histórico na era global: entre dinâmicas culturais inclusivas e excludentes

Directory of Open Access Journals (Sweden)

James Washington Alves dos Santos

2017-12-01

Full Text Available Este artigo buscou estudar com base em pesquisa bibliográfica os conceitos de espaço social e tempo histórico trazendo para o debate a contribuição de diversos autores das Ciências Humanas. No nosso objetivo é problematizar temas como: espaço social, tempo histórico, globalização e cosmopolitismo, populismo e xenofobia, elementos que geram nos ajudam a entender a crise da pertença e das origens. Na medida em que o tribalismo aumenta, reforça a existência de Estados murados na tentativa de manter uma soberania em declínio. Os ideais da luta de classes enquanto uma história política e filosófica perdem sentido e o ser humano se atomiza cada vez mais. Estes sinais para Domenico Losurdo e F. V. Paleólogo revelam a emergência de um direito social sob sequestro. Assim, fomos da emergência humanitária ao estado de exceção, como disse S. Sassen, gerando migrações massivas a Europa, pulsões, brutalidade e complexidade na economia global. São os tempos dos muros caídos (fronteiras e dos muros erguidos (desigualdades.   Palavras-Chave: espaço social, tempo histórico, globalização, populismo, xenofobia

Escolha de modo no acesso terrestre a aeroportos considerando a confiabilidade do tempo de viagem

Directory of Open Access Journals (Sweden)

Bianca Bianchi Alves

2011-09-01

Full Text Available

Resumo: O objetivo do trabalho é identificar variações sistemáticas da importância atribuída por viajantes aéreos aos fatores que influenciam a escolha de modo para acesso terrestre ao Aeroporto Internacional de São Paulo. A análise utilizou dados de uma pesquisa de preferência declarada conduzida com residentes na região viajando para destinos internacionais. Os indivíduos ordenavam 4 alternativas: automóvel, táxi, ônibus expresso existente e um trem expresso proposto, descritas pelos atributos de custo, tempo esperado de viagem e confiabilidade do tempo de viagem, expressa através de uma margem de segurança. Modelos de escolha discreta foram estimados, considerando os efeitos de painel, aninhamento e de inércia. Os resultados indicaram que viajantes a negócios e de alta renda são menos sensíveis ao custo da viagem de acesso ao aeroporto. A importância da confiabilidade do tempo de viagem é maior do que a atribuída ao tempo esperado de viagem e não foi afetada por variações sistemáticas.

Palavras-chave: valor de confiabilidade; acesso terrestre a aeroportos; escolha de modo; modelo logit misto; preferência declarada.

Abstract: The paper analyses systematic variation of tastes and preferences of air travelers regarding the choice of mode for the ground access to the São Paulo International Airport. A stated preference survey was conducted with individuals traveling to international destinations. Each respondent ranked 4 alternatives: auto, taxi, the existing express bus, and a proposed express train. Attributes describing modes were travel cost, average travel time and travel time reliability, expressed as a safety margin – the time period allocated by the individual for arriving at the airport at the preferred time. Discrete mode choice models were estimated, considering panel, nesting and inertia effects. Results indicated that business and higher income

Applied evolutionary economics and economic geography

NARCIS (Netherlands)

Frenken, K.

2007-01-01

Applied Evolutionary Economics and Economic Geography" aims to further advance empirical methodologies in evolutionary economics, with a special emphasis on geography and firm location. It does so by bringing together a select group of leading scholars including economists, geographers and

Accelerated crossing of fitness valleys through division of labor and cheating in asexual populations

Science.gov (United States)

Komarova, Natalia L.; Urwin, Erin; Wodarz, Dominik

2012-12-01

Complex traits can require the accumulation of multiple mutations that are individually deleterious. Their evolution requires a fitness valley to be crossed, which can take relatively long time spans. A new evolutionary mechanism is described that accelerates the emergence of complex phenotypes, based on a ``division of labor'' game and the occurrence of cheaters. If each intermediate mutation leads to a product that can be shared with others, the complex type can arise relatively quickly as an emergent property among cooperating individuals, without any given individual having to accumulate all mutations. Moreover, the emergence of cheaters that destroy cooperative interactions can lead to the emergence of individuals that have accumulated all necessary mutations on a time scale that is significantly faster than observed in the absence of cooperation and cheating. Application of this mechanism to somatic and microbial evolution is discussed, including evolutionary processes in tumors, biofilms, and viral infections.

Diversity-Guided Evolutionary Algorithms

DEFF Research Database (Denmark)

Ursem, Rasmus Kjær

2002-01-01

Population diversity is undoubtably a key issue in the performance of evolutionary algorithms. A common hypothesis is that high diversity is important to avoid premature convergence and to escape local optima. Various diversity measures have been used to analyze algorithms, but so far few...... algorithms have used a measure to guide the search. The diversity-guided evolutionary algorithm (DGEA) uses the wellknown distance-to-average-point measure to alternate between phases of exploration (mutation) and phases of exploitation (recombination and selection). The DGEA showed remarkable results...

Phylogenetic inference with weighted codon evolutionary distances.

Science.gov (United States)

Criscuolo, Alexis; Michel, Christian J

2009-04-01

We develop a new approach to estimate a matrix of pairwise evolutionary distances from a codon-based alignment based on a codon evolutionary model. The method first computes a standard distance matrix for each of the three codon positions. Then these three distance matrices are weighted according to an estimate of the global evolutionary rate of each codon position and averaged into a unique distance matrix. Using a large set of both real and simulated codon-based alignments of nucleotide sequences, we show that this approach leads to distance matrices that have a significantly better treelikeness compared to those obtained by standard nucleotide evolutionary distances. We also propose an alternative weighting to eliminate the part of the noise often associated with some codon positions, particularly the third position, which is known to induce a fast evolutionary rate. Simulation results show that fast distance-based tree reconstruction algorithms on distance matrices based on this codon position weighting can lead to phylogenetic trees that are at least as accurate as, if not better, than those inferred by maximum likelihood. Finally, a well-known multigene dataset composed of eight yeast species and 106 codon-based alignments is reanalyzed and shows that our codon evolutionary distances allow building a phylogenetic tree which is similar to those obtained by non-distance-based methods (e.g., maximum parsimony and maximum likelihood) and also significantly improved compared to standard nucleotide evolutionary distance estimates.

Evolutionary analyses of non-genealogical bonds produced by introgressive descent.

Science.gov (United States)

Bapteste, Eric; Lopez, Philippe; Bouchard, Frédéric; Baquero, Fernando; McInerney, James O; Burian, Richard M

2012-11-06

All evolutionary biologists are familiar with evolutionary units that evolve by vertical descent in a tree-like fashion in single lineages. However, many other kinds of processes contribute to evolutionary diversity. In vertical descent, the genetic material of a particular evolutionary unit is propagated by replication inside its own lineage. In what we call introgressive descent, the genetic material of a particular evolutionary unit propagates into different host structures and is replicated within these host structures. Thus, introgressive descent generates a variety of evolutionary units and leaves recognizable patterns in resemblance networks. We characterize six kinds of evolutionary units, of which five involve mosaic lineages generated by introgressive descent. To facilitate detection of these units in resemblance networks, we introduce terminology based on two notions, P3s (subgraphs of three nodes: A, B, and C) and mosaic P3s, and suggest an apparatus for systematic detection of introgressive descent. Mosaic P3s correspond to a distinct type of evolutionary bond that is orthogonal to the bonds of kinship and genealogy usually examined by evolutionary biologists. We argue that recognition of these evolutionary bonds stimulates radical rethinking of key questions in evolutionary biology (e.g., the relations among evolutionary players in very early phases of evolutionary history, the origin and emergence of novelties, and the production of new lineages). This line of research will expand the study of biological complexity beyond the usual genealogical bonds, revealing additional sources of biodiversity. It provides an important step to a more realistic pluralist treatment of evolutionary complexity.

Nodulose acelerada na artrite reumatóide durante terapia com Leflunomida Accelerated nodulosis in rheumatoid arthritis during Leflunomide therapy

Directory of Open Access Journals (Sweden)

Dario Júnior de Freitas Rosa

2007-06-01

Full Text Available Nodulose acelerada (NA é o desenvolvimento de um grande número de nódulos durante um curto intervalo de tempo em pacientes adultos com artrite reumatóide (AR soropositiva ou soronegativa. Esses nódulos são usualmente associados à terapia com o metotrexato. Existem três relatos de casos descritos de pacientes que desenvolveram NA periférica durante o tratamento com leflunomida. Descrevemos o caso de uma paciente de 60 anos com diagnóstico de AR soropositiva que desenvolveu o quadro de NA depois de quatro meses de terapia com leflunomida. Após um período de oito meses de interrupção do uso da droga, houve regressão completa da nodulose.Accelerated nodulosis is the development of a large number of nodules during a short time in adult patients presenting either seropositive or seronegative rheumatoid arthritis. These nodules are usually described as associated to methotrexate therapy. There have been three case reports of patients who developed peripheral accelerated nodulosis while receiving leflunomide. We describe a 60-years old woman with seropositive rheumatoid arthritis who developed accelerated nodulosis after four months receiving leflunomide therapy. The patient had a complete regression of the subcutaneous nodules eight months after cessation of leflunomide.

Evolutionary perspectives on ageing.

Science.gov (United States)

Reichard, Martin

2017-10-01

From an evolutionary perspective, ageing is a decrease in fitness with chronological age - expressed by an increase in mortality risk and/or decline in reproductive success and mediated by deterioration of functional performance. While this makes ageing intuitively paradoxical - detrimental to individual fitness - evolutionary theory offers answers as to why ageing has evolved. In this review, I first briefly examine the classic evolutionary theories of ageing and their empirical tests, and highlight recent findings that have advanced our understanding of the evolution of ageing (condition-dependent survival, positive pleiotropy). I then provide an overview of recent theoretical extensions and modifications that accommodate those new discoveries. I discuss the role of indeterminate (asymptotic) growth for lifetime increases in fecundity and ageing trajectories. I outline alternative views that challenge a universal existence of senescence - namely the lack of a germ-soma distinction and the ability of tissue replacement and retrogression to younger developmental stages in modular organisms. I argue that rejuvenation at the organismal level is plausible, but includes a return to a simple developmental stage. This may exempt a particular genotype from somatic defects but, correspondingly, removes any information acquired during development. A resolution of the question of whether a rejuvenated individual is the same entity is central to the recognition of whether current evolutionary theories of ageing, with their extensions and modifications, can explain the patterns of ageing across the Tree of Life. Copyright © 2017 Elsevier Ltd. All rights reserved.

Análise tempo-intensidade dos estímulos doce e amargo de extrato de folhas de estévia [Stevia rebaudiana (Bert. Bertoni] em doçura equivalente a sacarose

Directory of Open Access Journals (Sweden)

CARDELLO Helena Maria André Bolini

1999-01-01

Full Text Available O extrato de folhas de estévia (Stevia rebaudiana Bertoni é o único edulcorante utilizado na substituição da sacarose, que pode ser produzido totalmente no Brasil. O objetivo deste estudo foi determinar os comportamentos de características temporais dos estímulos doce e amargo da estevia em doçuras equivalentes a soluções de sacarose (DESS a 3 e 10%. As curvas tempo-intensidade (T-I para cada substância foram coletadas utilizando-se o programa "Sistema de Coleta de Dados Tempo-Intensidade - SCDTI" para Windows, onde os provadores registravam com auxílio do "mouse" a percepção de cada estímulo solicitado em função do tempo, para cada amostra. Os parâmetros das curvas T-I coletados foram: tempo de intensidade máxima (TImax, intensidade máxima (Imax, tempo onde a intensidade máxima começa a declinar (Td, tempo de platô (Platô, área sob a curva (Área e tempo total de duração do estímulo (Ttot. Os parâmetros Td, Ttot, Área e Platô das curvas T-I para o estímulo doce nos dois níveis de doçura foram significativamente superiores para estévia, enquanto TImax e Imax foram significativamente menores (p£0,05, sendo que as diferenças entre os valores para as duas substâncias foram muito maiores a DESS a 10%. A sacarose não apresentou nenhum registro para o estímulo amargo tanto a 3 como a 10%, enquanto a estévia apresentou curvas T-I características, com intensidade e o tempo total de duração dependente da concentração.

Interpreting Evolutionary Diagrams: When Topology and Process Conflict

Science.gov (United States)

Catley, Kefyn M.; Novick, Laura R.; Shade, Courtney K.

2010-01-01

The authors argue that some diagrams in biology textbooks and the popular press presented as depicting evolutionary relationships suggest an inappropriate (anagenic) conception of evolutionary history. The goal of this research was to provide baseline data that begin to document how college students conceptualize the evolutionary relationships…

Using Evolutionary Theory to Guide Mental Health Research.

Science.gov (United States)

Durisko, Zachary; Mulsant, Benoit H; McKenzie, Kwame; Andrews, Paul W

2016-03-01

Evolutionary approaches to medicine can shed light on the origins and etiology of disease. Such an approach may be especially useful in psychiatry, which frequently addresses conditions with heterogeneous presentation and unknown causes. We review several previous applications of evolutionary theory that highlight the ways in which psychiatric conditions may persist despite and because of natural selection. One lesson from the evolutionary approach is that some conditions currently classified as disorders (because they cause distress and impairment) may actually be caused by functioning adaptations operating "normally" (as designed by natural selection). Such conditions suggest an alternative illness model that may generate alternative intervention strategies. Thus, the evolutionary approach suggests that psychiatry should sometimes think differently about distress and impairment. The complexity of the human brain, including normal functioning and potential for dysfunctions, has developed over evolutionary time and has been shaped by natural selection. Understanding the evolutionary origins of psychiatric conditions is therefore a crucial component to a complete understanding of etiology. © The Author(s) 2016.

Evolutionary engineering of industrial microorganisms-strategies and applications.

Science.gov (United States)

Zhu, Zhengming; Zhang, Juan; Ji, Xiaomei; Fang, Zhen; Wu, Zhimeng; Chen, Jian; Du, Guocheng

2018-06-01

Microbial cells have been widely used in the industry to obtain various biochemical products, and evolutionary engineering is a common method in biological research to improve their traits, such as high environmental tolerance and improvement of product yield. To obtain better integrate functions of microbial cells, evolutionary engineering combined with other biotechnologies have attracted more attention in recent years. Classical laboratory evolution has been proven effective to letting more beneficial mutations occur in different genes but also has some inherent limitations such as a long evolutionary period and uncontrolled mutation frequencies. However, recent studies showed that some new strategies may gradually overcome these limitations. In this review, we summarize the evolutionary strategies commonly used in industrial microorganisms and discuss the combination of evolutionary engineering with other biotechnologies such as systems biology and inverse metabolic engineering. Finally, we prospect the importance and application prospect of evolutionary engineering as a powerful tool especially in optimization of industrial microbial cell factories.

Democratizing evolutionary biology, lessons from insects

DEFF Research Database (Denmark)

Dunn, Robert Roberdeau; Beasley, DeAnna E.

2016-01-01

The engagement of the public in the scientific process is an old practice. Yet with recent advances in technology, the role of the citizen scientist in studying evolutionary processes has increased. Insects provide ideal models for understanding these evolutionary processes at large scales. This ...

Evolutionary theory and the naturalist fallacy

DEFF Research Database (Denmark)

Grodal, Torben Kragh

2008-01-01

that great work of art are also automatically fitness-enhancing in the present day environment, at that there are simple correllations between whether a work of art has a high aesthetic value and whether it is fitness-enhancing or not.  Keywords :  Evolutionary aesthetics, film theory, literary theory......The article is an invited response to a target article by Joseph Carroll entitled "An evolutionary paradigm for literary study". It argues that the target article  misuse the fact that works of art are based on adaptations that were fitness-enhancing in the era of evolutionary adaptations to claim...

Trauma torácico: importância da antibioticoterapia sobre o tempo de internação

Directory of Open Access Journals (Sweden)

Fontelles Mauro José

2001-01-01

Full Text Available No que tange a comprovada eficácia da drenagem pleural fechada, grande controvérsia ainda persiste em relação ao uso associado da antibioticoterapia. Os autores estudaram 167 pacientes, com trauma isolado do tórax, com objetivo de avaliar a importância do uso do antibiótico sobre o tempo de internação pós-drenagem pleural fechada. Dois grupos de pacientes foram incluídos num estudo longitudinal e prospectivo de acompanhamento de coortes. O grupo controle incluiu 104 pacientes sem uso da antibioticoterapia; no grupo experimental, 63 pacientes receberam a cefalotina sódica no pós-operatório (500 mg IV - 6/6 h. Entre os pacientes estudados, 12 (7.2% apresentavam trauma fechado; 98 (58.6%, ferimento por arma branca; 41 (24.6% ferida por projétil de arma de fogo e, 16 (9.6% lesões por outros agentes vulnerantes. Entre os pacientes do grupo controle o tempo médio de permanência hospitalar foi de 5.7± 3.2 dias e, no grupo com antibiótico, 5.7± 2.9 dias. Os resultados mostraram que nos pacientes que não receberam antibiótico e evoluíram com algum tipo de complicação pleuropulmonar, o tempo de internação foi, em média, 3.2 dias maior que nos demais.

Evolutionary public health: introducing the concept.

Science.gov (United States)

Wells, Jonathan C K; Nesse, Randolph M; Sear, Rebecca; Johnstone, Rufus A; Stearns, Stephen C

2017-07-29

The emerging discipline of evolutionary medicine is breaking new ground in understanding why people become ill. However, the value of evolutionary analyses of human physiology and behaviour is only beginning to be recognised in the field of public health. Core principles come from life history theory, which analyses the allocation of finite amounts of energy between four competing functions-maintenance, growth, reproduction, and defence. A central tenet of evolutionary theory is that organisms are selected to allocate energy and time to maximise reproductive success, rather than health or longevity. Ecological interactions that influence mortality risk, nutrient availability, and pathogen burden shape energy allocation strategies throughout the life course, thereby affecting diverse health outcomes. Public health interventions could improve their own effectiveness by incorporating an evolutionary perspective. In particular, evolutionary approaches offer new opportunities to address the complex challenges of global health, in which populations are differentially exposed to the metabolic consequences of poverty, high fertility, infectious diseases, and rapid changes in nutrition and lifestyle. The effect of specific interventions is predicted to depend on broader factors shaping life expectancy. Among the important tools in this approach are mathematical models, which can explore probable benefits and limitations of interventions in silico, before their implementation in human populations. Copyright © 2017 Elsevier Ltd. All rights reserved.

A teleofunctional account of evolutionary mismatch.

Science.gov (United States)

Cofnas, Nathan

When the environment in which an organism lives deviates in some essential way from that to which it is adapted, this is described as "evolutionary mismatch," or "evolutionary novelty." The notion of mismatch plays an important role, explicitly or implicitly, in evolution-informed cognitive psychology, clinical psychology, and medicine. The evolutionary novelty of our contemporary environment is thought to have significant implications for our health and well-being. However, scientists have generally been working without a clear definition of mismatch. This paper defines mismatch as deviations in the environment that render biological traits unable, or impaired in their ability, to produce their selected effects (i.e., to perform their proper functions in Neander's sense). The machinery developed by Millikan in connection with her account of proper function, and with her related teleosemantic account of representation, is used to identify four major types, and several subtypes, of evolutionary mismatch. While the taxonomy offered here does not in itself resolve any scientific debates, the hope is that it can be used to better formulate empirical hypotheses concerning the effects of mismatch. To illustrate, it is used to show that the controversial hypothesis that general intelligence evolved as an adaptation to handle evolutionary novelty can, contra some critics, be formulated in a conceptually coherent way.

The evolutionary ecology of molecular replicators.

Science.gov (United States)

Nee, Sean

2016-08-01

By reasonable criteria, life on the Earth consists mainly of molecular replicators. These include viruses, transposons, transpovirons, coviruses and many more, with continuous new discoveries like Sputnik Virophage. Their study is inherently multidisciplinary, spanning microbiology, genetics, immunology and evolutionary theory, and the current view is that taking a unified approach has great power and promise. We support this with a new, unified, model of their evolutionary ecology, using contemporary evolutionary theory coupling the Price equation with game theory, studying the consequences of the molecular replicators' promiscuous use of each others' gene products for their natural history and evolutionary ecology. Even at this simple expository level, we can make a firm prediction of a new class of replicators exploiting viruses such as lentiviruses like SIVs, a family which includes HIV: these have been explicitly stated in the primary literature to be non-existent. Closely connected to this departure is the view that multicellular organism immunology is more about the management of chronic infections rather than the elimination of acute ones and new understandings emerging are changing our view of the kind of theatre we ourselves provide for the evolutionary play of molecular replicators. This study adds molecular replicators to bacteria in the emerging field of sociomicrobiology.

Multiobjective Multifactorial Optimization in Evolutionary Multitasking.

Science.gov (United States)

Gupta, Abhishek; Ong, Yew-Soon; Feng, Liang; Tan, Kay Chen

2016-05-03

In recent decades, the field of multiobjective optimization has attracted considerable interest among evolutionary computation researchers. One of the main features that makes evolutionary methods particularly appealing for multiobjective problems is the implicit parallelism offered by a population, which enables simultaneous convergence toward the entire Pareto front. While a plethora of related algorithms have been proposed till date, a common attribute among them is that they focus on efficiently solving only a single optimization problem at a time. Despite the known power of implicit parallelism, seldom has an attempt been made to multitask, i.e., to solve multiple optimization problems simultaneously. It is contended that the notion of evolutionary multitasking leads to the possibility of automated transfer of information across different optimization exercises that may share underlying similarities, thereby facilitating improved convergence characteristics. In particular, the potential for automated transfer is deemed invaluable from the standpoint of engineering design exercises where manual knowledge adaptation and reuse are routine. Accordingly, in this paper, we present a realization of the evolutionary multitasking paradigm within the domain of multiobjective optimization. The efficacy of the associated evolutionary algorithm is demonstrated on some benchmark test functions as well as on a real-world manufacturing process design problem from the composites industry.

Evolutionary heritage influences Amazon tree ecology

Science.gov (United States)

Coelho de Souza, Fernanda; Dexter, Kyle G.; Phillips, Oliver L.; Brienen, Roel J. W.; Chave, Jerome; Galbraith, David R.; Lopez Gonzalez, Gabriela; Monteagudo Mendoza, Abel; Pennington, R. Toby; Poorter, Lourens; Alexiades, Miguel; Álvarez-Dávila, Esteban; Andrade, Ana; Aragão, Luis E. O. C.; Araujo-Murakami, Alejandro; Arets, Eric J. M. M.; Aymard C, Gerardo A.; Baraloto, Christopher; Barroso, Jorcely G.; Bonal, Damien; Boot, Rene G. A.; Camargo, José L. C.; Comiskey, James A.; Valverde, Fernando Cornejo; de Camargo, Plínio B.; Di Fiore, Anthony; Erwin, Terry L.; Feldpausch, Ted R.; Ferreira, Leandro; Fyllas, Nikolaos M.; Gloor, Emanuel; Herault, Bruno; Herrera, Rafael; Higuchi, Niro; Honorio Coronado, Eurídice N.; Killeen, Timothy J.; Laurance, William F.; Laurance, Susan; Lloyd, Jon; Lovejoy, Thomas E.; Malhi, Yadvinder; Maracahipes, Leandro; Marimon, Beatriz S.; Marimon-Junior, Ben H.; Mendoza, Casimiro; Morandi, Paulo; Neill, David A.; Vargas, Percy Núñez; Oliveira, Edmar A.; Lenza, Eddie; Palacios, Walter A.; Peñuela-Mora, Maria C.; Pipoly, John J.; Pitman, Nigel C. A.; Prieto, Adriana; Quesada, Carlos A.; Ramirez-Angulo, Hirma; Rudas, Agustin; Ruokolainen, Kalle; Salomão, Rafael P.; Silveira, Marcos; ter Steege, Hans; Thomas-Caesar, Raquel; van der Hout, Peter; van der Heijden, Geertje M. F.; van der Meer, Peter J.; Vasquez, Rodolfo V.; Vieira, Simone A.; Vilanova, Emilio; Vos, Vincent A.; Wang, Ophelia; Young, Kenneth R.; Zagt, Roderick J.; Baker, Timothy R.

2016-01-01

Lineages tend to retain ecological characteristics of their ancestors through time. However, for some traits, selection during evolutionary history may have also played a role in determining trait values. To address the relative importance of these processes requires large-scale quantification of traits and evolutionary relationships among species. The Amazonian tree flora comprises a high diversity of angiosperm lineages and species with widely differing life-history characteristics, providing an excellent system to investigate the combined influences of evolutionary heritage and selection in determining trait variation. We used trait data related to the major axes of life-history variation among tropical trees (e.g. growth and mortality rates) from 577 inventory plots in closed-canopy forest, mapped onto a phylogenetic hypothesis spanning more than 300 genera including all major angiosperm clades to test for evolutionary constraints on traits. We found significant phylogenetic signal (PS) for all traits, consistent with evolutionarily related genera having more similar characteristics than expected by chance. Although there is also evidence for repeated evolution of pioneer and shade tolerant life-history strategies within independent lineages, the existence of significant PS allows clearer predictions of the links between evolutionary diversity, ecosystem function and the response of tropical forests to global change. PMID:27974517

Evolutionary heritage influences Amazon tree ecology.

Science.gov (United States)

Coelho de Souza, Fernanda; Dexter, Kyle G; Phillips, Oliver L; Brienen, Roel J W; Chave, Jerome; Galbraith, David R; Lopez Gonzalez, Gabriela; Monteagudo Mendoza, Abel; Pennington, R Toby; Poorter, Lourens; Alexiades, Miguel; Álvarez-Dávila, Esteban; Andrade, Ana; Aragão, Luis E O C; Araujo-Murakami, Alejandro; Arets, Eric J M M; Aymard C, Gerardo A; Baraloto, Christopher; Barroso, Jorcely G; Bonal, Damien; Boot, Rene G A; Camargo, José L C; Comiskey, James A; Valverde, Fernando Cornejo; de Camargo, Plínio B; Di Fiore, Anthony; Elias, Fernando; Erwin, Terry L; Feldpausch, Ted R; Ferreira, Leandro; Fyllas, Nikolaos M; Gloor, Emanuel; Herault, Bruno; Herrera, Rafael; Higuchi, Niro; Honorio Coronado, Eurídice N; Killeen, Timothy J; Laurance, William F; Laurance, Susan; Lloyd, Jon; Lovejoy, Thomas E; Malhi, Yadvinder; Maracahipes, Leandro; Marimon, Beatriz S; Marimon-Junior, Ben H; Mendoza, Casimiro; Morandi, Paulo; Neill, David A; Vargas, Percy Núñez; Oliveira, Edmar A; Lenza, Eddie; Palacios, Walter A; Peñuela-Mora, Maria C; Pipoly, John J; Pitman, Nigel C A; Prieto, Adriana; Quesada, Carlos A; Ramirez-Angulo, Hirma; Rudas, Agustin; Ruokolainen, Kalle; Salomão, Rafael P; Silveira, Marcos; Stropp, Juliana; Ter Steege, Hans; Thomas-Caesar, Raquel; van der Hout, Peter; van der Heijden, Geertje M F; van der Meer, Peter J; Vasquez, Rodolfo V; Vieira, Simone A; Vilanova, Emilio; Vos, Vincent A; Wang, Ophelia; Young, Kenneth R; Zagt, Roderick J; Baker, Timothy R

2016-12-14

Lineages tend to retain ecological characteristics of their ancestors through time. However, for some traits, selection during evolutionary history may have also played a role in determining trait values. To address the relative importance of these processes requires large-scale quantification of traits and evolutionary relationships among species. The Amazonian tree flora comprises a high diversity of angiosperm lineages and species with widely differing life-history characteristics, providing an excellent system to investigate the combined influences of evolutionary heritage and selection in determining trait variation. We used trait data related to the major axes of life-history variation among tropical trees (e.g. growth and mortality rates) from 577 inventory plots in closed-canopy forest, mapped onto a phylogenetic hypothesis spanning more than 300 genera including all major angiosperm clades to test for evolutionary constraints on traits. We found significant phylogenetic signal (PS) for all traits, consistent with evolutionarily related genera having more similar characteristics than expected by chance. Although there is also evidence for repeated evolution of pioneer and shade tolerant life-history strategies within independent lineages, the existence of significant PS allows clearer predictions of the links between evolutionary diversity, ecosystem function and the response of tropical forests to global change. © 2016 The Authors.

Evolutionary cell biology: two origins, one objective.

Science.gov (United States)

Lynch, Michael; Field, Mark C; Goodson, Holly V; Malik, Harmit S; Pereira-Leal, José B; Roos, David S; Turkewitz, Aaron P; Sazer, Shelley

2014-12-02

All aspects of biological diversification ultimately trace to evolutionary modifications at the cellular level. This central role of cells frames the basic questions as to how cells work and how cells come to be the way they are. Although these two lines of inquiry lie respectively within the traditional provenance of cell biology and evolutionary biology, a comprehensive synthesis of evolutionary and cell-biological thinking is lacking. We define evolutionary cell biology as the fusion of these two eponymous fields with the theoretical and quantitative branches of biochemistry, biophysics, and population genetics. The key goals are to develop a mechanistic understanding of general evolutionary processes, while specifically infusing cell biology with an evolutionary perspective. The full development of this interdisciplinary field has the potential to solve numerous problems in diverse areas of biology, including the degree to which selection, effectively neutral processes, historical contingencies, and/or constraints at the chemical and biophysical levels dictate patterns of variation for intracellular features. These problems can now be examined at both the within- and among-species levels, with single-cell methodologies even allowing quantification of variation within genotypes. Some results from this emerging field have already had a substantial impact on cell biology, and future findings will significantly influence applications in agriculture, medicine, environmental science, and synthetic biology.

Determinação e análise das constantes de tempo de um sensor anelar de temperatura em leito fixo - DOI: 10.4025/actascitechnol.v25i1.2225

Directory of Open Access Journals (Sweden)

Luiz Mario de Matos Jorge

2003-04-01

Full Text Available Neste trabalho foi desenvolvida uma metodologia teórico-experimental que possibilitou a determinação e a análise das constantes de tempo dos cinco termopares que compõem um sensor anelar de temperatura instalado em leito fixo. Para tal, foram efetuadas perturbações tipo degrau na temperatura do ar que passa pelo sensor, sendo as respostas térmicas registradas mediante medidas periódicas de temperatura até que o sensor alcançasse a condição de regime permanente. Posteriormente, as constantes de tempo foram estimadas a partir do ajuste de um modelo matemático do sensor por regressões lineares. Tanto o modelo matemático como a técnica utilizada para o ajuste das constantes de tempo foram adequados. Cada um dos termopares que compõem o sensor anelar apresentou constantes de tempo distintas. O termopar anelar externo, r = 0,027m, e o termopar central, r = 0m, apresentam o maior e o menor valor de constante de tempo, respectivamente, independentemente da vazão utilizada.

How to Identify and Interpret Evolutionary Tree Diagrams

Science.gov (United States)

Kong, Yi; Anderson, Trevor; Pelaez, Nancy

2016-01-01

Evolutionary trees are key tools for modern biology and are commonly portrayed in textbooks to promote learning about biological evolution. However, many people have difficulty in understanding what evolutionary trees are meant to portray. In fact, some ideas that current professional biologists depict with evolutionary trees are neither clearly…

Evolutionary biology of bacterial and fungal pathogens

National Research Council Canada - National Science Library

Baquero, F

2008-01-01

... and Evolutionary Dynamics of Pathogens * 21 Keith A. Crandall and Marcos Pérez-Losada II. Evolutionary Genetics of Microbial Pathogens 4. Environmental and Social Influences on Infectious Disea...

Regional systems of innovation: an evolutionary perspective

OpenAIRE

P Cooke; M G Uranga; G Etxebarria

1998-01-01

The authors develop the concept of regional systems of innovation and relate it to preexisting research on national systems of innovation. They argue that work conducted in the 'new regional science' field is complementary to systems of innovation approaches. They seek to link new regional work to evolutionary economics, and argue for the development of evolutionary regional science. Common elements of interest to evolutionary innovation research and new regional science are important in unde...

Molluscan Evolutionary Genomics

Energy Technology Data Exchange (ETDEWEB)

Simison, W. Brian; Boore, Jeffrey L.

2005-12-01

In the last 20 years there have been dramatic advances in techniques of high-throughput DNA sequencing, most recently accelerated by the Human Genome Project, a program that has determined the three billion base pair code on which we are based. Now this tremendous capability is being directed at other genome targets that are being sampled across the broad range of life. This opens up opportunities as never before for evolutionary and organismal biologists to address questions of both processes and patterns of organismal change. We stand at the dawn of a new 'modern synthesis' period, paralleling that of the early 20th century when the fledgling field of genetics first identified the underlying basis for Darwin's theory. We must now unite the efforts of systematists, paleontologists, mathematicians, computer programmers, molecular biologists, developmental biologists, and others in the pursuit of discovering what genomics can teach us about the diversity of life. Genome-level sampling for mollusks to date has mostly been limited to mitochondrial genomes and it is likely that these will continue to provide the best targets for broad phylogenetic sampling in the near future. However, we are just beginning to see an inroad into complete nuclear genome sequencing, with several mollusks and other eutrochozoans having been selected for work about to begin. Here, we provide an overview of the state of molluscan mitochondrial genomics, highlight a few of the discoveries from this research, outline the promise of broadening this dataset, describe upcoming projects to sequence whole mollusk nuclear genomes, and challenge the community to prepare for making the best use of these data.

Evolutionary robotics

Indian Academy of Sciences (India)

In evolutionary robotics, a suitable robot control system is developed automatically through evolution due to the interactions between the robot and its environment. It is a complicated task, as the robot and the environment constitute a highly dynamical system. Several methods have been tried by various investigators to ...

Influência do tempo de fotopolimerização de diferentes resinas compostas na sorpção de água = Influence of polymerization time of different composites on water sorption

Directory of Open Access Journals (Sweden)

Guimarães, Fabrício Barbosa Rocha

2008-01-01

Full Text Available Objetivo: Verificar a influência do tempo de polimerização de resinas compostas na absorção de água por diferentes resinas compostas. Metodologia: As resinas multiuso Z250®, compactável P60® e de micropartículas A110® foram utilizadas para a confecção de corpos-de-prova (n=5 por grupo de acordo com o tempo de fotopolimerização (o indicado pelo fabricante, a metade e o dobro do tempo preconizado. A quantidade de água absorvida pelos espécimes foi medida pela variação da massa dos mesmos, que foram pesados imediatamente após sua confecção, a cada 24h por 10 dias, e após 15 e 30 dias. Os dados foram analisados por ANOVA e teste de Tukey. Resultados: A absorção de água das resinas compostas foi diferente quando o tempo de polimerização foi alterado. A resina de micropartículas teve o melhor comportamento perante a mudança no tempo de fotopolimerização, enquanto que a resina de multiuso foi a que mais absorveu água quando o tempo foi alterado para menos (P<0,05. Conclusão: O tempo de polimerização sugerido pelo fabricante deve ser respeitado para assegurar a manutenção das propriedades desses materiais, independentemente do tipo de resina utilizado

Bromide-free TEMPO-mediated oxidation of primary alcohol groups in starch and methyl alpha-D-glucopyranoside.

Science.gov (United States)

Bragd, P L; Besemer, A C; van Bekkum, H

2000-09-22

TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl)-mediated oxidation of potato starch and methyl alpha-D-glucopyranoside (MGP) was performed in the absence of sodium bromide (NaBr) as co-catalyst, solely using sodium hypochlorite (NaOCl) as the primary oxidant. The low reaction rate associated with a bromide-free process was increased by performing the oxidation at increased temperatures. The reaction proceeded stoichiometrically and with high selectivity and with only minor depolymerisation, provided that temperature and pH were kept or = 25 degrees C) and under more alkaline conditions (pH > or = 9.0) degradation of the starch skeleton occurred. Simultaneously, side-reactions of the nitrosonium ion lowered the yield of the oxidation. Despite the absence of the NaBr catalyst, the reaction rate-controlling step was found to be the oxidation of the primary hydroxyl groups with the nitrosonium ion. The reaction was first-order in MGP and in TEMPO.

Evolutionary mysteries in meiosis.

Science.gov (United States)

Lenormand, Thomas; Engelstädter, Jan; Johnston, Susan E; Wijnker, Erik; Haag, Christoph R

2016-10-19

Meiosis is a key event of sexual life cycles in eukaryotes. Its mechanistic details have been uncovered in several model organisms, and most of its essential features have received various and often contradictory evolutionary interpretations. In this perspective, we present an overview of these often 'weird' features. We discuss the origin of meiosis (origin of ploidy reduction and recombination, two-step meiosis), its secondary modifications (in polyploids or asexuals, inverted meiosis), its importance in punctuating life cycles (meiotic arrests, epigenetic resetting, meiotic asymmetry, meiotic fairness) and features associated with recombination (disjunction constraints, heterochiasmy, crossover interference and hotspots). We present the various evolutionary scenarios and selective pressures that have been proposed to account for these features, and we highlight that their evolutionary significance often remains largely mysterious. Resolving these mysteries will likely provide decisive steps towards understanding why sex and recombination are found in the majority of eukaryotes.This article is part of the themed issue 'Weird sex: the underappreciated diversity of sexual reproduction'. © 2016 The Author(s).

Análise do campo elétrico atmosférico durante tempo bom e distúrbios geofísicos

OpenAIRE

Anaya, José Carlos Tacza

2015-01-01

Neste trabalho de dissertação apresenta-se a capabilidade de uma nova rede de sensores para monitorar o campo elétrico atmosférico em vários locais na América do Sul. O objetivo principal é obter a curva diária do campo elétrico atmosférico de tempo bom. Para isto foram realizadas médias mensais, sazonais e anuais. Essa curva é comparada com a curva característica em Tempo Universal conhecida como a Curva de Carnegie, a qual é relacionada com as correntes fluindo no Circuito Elétrico Atmosfér...

Estudo do efeito de novas técnicas de lupulização no tempo de prateleira da cerveja artesanal

OpenAIRE

Silva, Helder Rainha e

2015-01-01

Dissertação de mestrado integrado em Engenharia Biológica (área de especialização em Tecnologia Química e Alimentar) Uma vez que as cervejas produzidas pelo método artesanal não são pasteurizadas nem filtradas, deterioram-se mais rapidamente. Um possível método para aumento do tempo de prateleira da cerveja artesanal é o uso de estratégias com base na adição de lúpulo em diferentes tempos e fases do processo de produção de cerveja. Este projeto tem como principal objetivo o estudo...

A utilização dos ditos populares e da observação do tempo para a Climatologia Escolar no Ensino Fundamental II

Directory of Open Access Journals (Sweden)

Diego Corrêa Maia

2010-07-01

Full Text Available A atual realidade escolar no Brasil demonstra que o ensino de Climatologia não tem sido desenvolvido no Ensino Fundamental II, ou, quando ocorre, é ministrado baseado na Climatologia tradicional e separativa, cujos fatores e elementos do clima são analisados individualmente, retratando-se a natureza de forma estática e totalmente destituída do real. Através da observação dos elementos do clima, pretende-se demonstrar que o aprendizado dos “conteúdos climatológicos” pode ser auxiliado através dos ditos populares. O que se almeja neste artigo é demonstrar que, a partir da observação espontânea (diária do tempo e do clima, com o auxílio dos ditos populares, os alunos do Ensino Fundamental II podem compreender as relações do tempo e do clima, assim como sua previsão. É necessário para esta atividade um período contínuo de observação para estabelecer a sequência habitual dos tipos de tempo de uma determinada estação do ano. O modo popular de prever o tempo foi iniciado desde que o homem se fixou em cavernas; no entanto, este hábito vem se perdendo em função da urbanização da sociedade. Para reforçar a importância dos provérbios populares para prever o tempo, realizar-se-á um pequeno histórico do nascimento da meteorologia popular, até a sua relevância destacada nos Parâmetros Curriculares Nacionais de Geografia.

TEMPO/viologen electrochemical heterojunction for diffusion-controlled redox mediation: a highly rectifying bilayer-sandwiched device based on cross-reaction at the interface between dissimilar redox polymers.

Science.gov (United States)

Tokue, Hiroshi; Oyaizu, Kenichi; Sukegawa, Takashi; Nishide, Hiroyuki

2014-03-26

A couple of totally reversible redox-active molecules, which are different in redox potentials, 2,2,6,6-tetramethylpiperidin-1-oxyl (TEMPO) and viologen (V(2+)), were employed to give rise to a rectified redox conduction effect. Single-layer and bilayer devices were fabricated using polymers containing these sites as pendant groups per repeating unit. The devices were obtained by sandwiching the redox polymer layer(s) with indium tin oxide (ITO)/glass and Pt foil electrodes. Electrochemical measurements of the single-layer device composed of polynorbornene-bearing TEMPO (PTNB) exhibited a diffusion-limited current-voltage response based on the TEMPO(+)/TEMPO exchange reaction, which was almost equivalent to a redox gradient through the PTNB layer depending upon the thickness. The bilayer device gave rise to the current rectification because of the thermodynamically favored cross-reaction between TEMPO(+) and V(+) at the polymer/polymer interface. A current-voltage response obtained for the bilayer device demonstrated a two-step diffusion-limited current behavior as a result of the concurrent V(2+)/V(+) and V(+)/V(0) exchange reactions according to the voltage and suggested that the charge transport process through the device was most likely to be rate-determined by a redox gradient in the polymer layer. Current collection experiments revealed a charge transport balance throughout the device, as a result of the electrochemical stability and robustness of the polymers in both redox states.

Os Cadernos do Nosso Tempo e o interesse nacional

Directory of Open Access Journals (Sweden)

Cristina Buarque de Hollanda

2012-01-01

Full Text Available Cet article a pour but de rechercher et de mettre à jour l'intérêt national des auteurs-éditeurs des Cadernos do Nosso Tempo édités par l'Instituto Brasileiro de Economia, Sociologia e Política (IBESP entre décembre 1953 et mars 1956. A partir de la lecture systématique des Cadernos et d'une bibliographie pertinente, l'auteur traite des compréhensions dont il est question sur le bilan de la politique, le développement potentiel de la nation, ses entraves et, finalement, le legs politique de Getúlio Vargas. Pour les intellectuels do l'IBESP, le nationalisme bien compris est le Seul moyen permettant de surmonter l'expérience politique fragmentaire.

Evolutionary impact assessment: accounting for evolutionary consequences of fishing in an ecosystem approach to fisheries management.

Science.gov (United States)

Laugen, Ane T; Engelhard, Georg H; Whitlock, Rebecca; Arlinghaus, Robert; Dankel, Dorothy J; Dunlop, Erin S; Eikeset, Anne M; Enberg, Katja; Jørgensen, Christian; Matsumura, Shuichi; Nusslé, Sébastien; Urbach, Davnah; Baulier, Loїc; Boukal, David S; Ernande, Bruno; Johnston, Fiona D; Mollet, Fabian; Pardoe, Heidi; Therkildsen, Nina O; Uusi-Heikkilä, Silva; Vainikka, Anssi; Heino, Mikko; Rijnsdorp, Adriaan D; Dieckmann, Ulf

2014-03-01

Managing fisheries resources to maintain healthy ecosystems is one of the main goals of the ecosystem approach to fisheries (EAF). While a number of international treaties call for the implementation of EAF, there are still gaps in the underlying methodology. One aspect that has received substantial scientific attention recently is fisheries-induced evolution (FIE). Increasing evidence indicates that intensive fishing has the potential to exert strong directional selection on life-history traits, behaviour, physiology, and morphology of exploited fish. Of particular concern is that reversing evolutionary responses to fishing can be much more difficult than reversing demographic or phenotypically plastic responses. Furthermore, like climate change, multiple agents cause FIE, with effects accumulating over time. Consequently, FIE may alter the utility derived from fish stocks, which in turn can modify the monetary value living aquatic resources provide to society. Quantifying and predicting the evolutionary effects of fishing is therefore important for both ecological and economic reasons. An important reason this is not happening is the lack of an appropriate assessment framework. We therefore describe the evolutionary impact assessment (EvoIA) as a structured approach for assessing the evolutionary consequences of fishing and evaluating the predicted evolutionary outcomes of alternative management options. EvoIA can contribute to EAF by clarifying how evolution may alter stock properties and ecological relations, support the precautionary approach to fisheries management by addressing a previously overlooked source of uncertainty and risk, and thus contribute to sustainable fisheries.

Evolutionary changes of Hox genes and relevant regulatory factors provide novel insights into mammalian morphological modifications.

Science.gov (United States)

Li, Kui; Sun, Xiaohui; Chen, Meixiu; Sun, Yingying; Tian, Ran; Wang, Zhengfei; Xu, Shixia; Yang, Guang

2018-01-01

The diversity of body plans of mammals accelerates the innovation of lifestyles and the extensive adaptation to different habitats, including terrestrial, aerial and aquatic habitats. However, the genetic basis of those phenotypic modifications, which have occurred during mammalian evolution, remains poorly explored. In the present study, we synthetically surveyed the evolutionary pattern of Hox clusters that played a powerful role in the morphogenesis along the head-tail axis of animal embryos and the main regulatory factors (Mll, Bmi1 and E2f6) that control the expression of Hox genes. A deflected density of repetitive elements and lineage-specific radical mutations of Mll have been determined in marine mammals with morphological changes, suggesting that evolutionary changes may alter Hox gene expression in these lineages, leading to the morphological modification of these lineages. Although no positive selection was detected at certain ancestor nodes of lineages, the increased ω values of Hox genes implied the relaxation of functional constraints of these genes during the mammalian evolutionary process. More importantly, 49 positively-selected sites were identified in mammalian lineages with phenotypic modifications, indicating adaptive evolution acting on Hox genes and regulatory factors. In addition, 3 parallel amino acid substitutions in some Hox genes were examined in marine mammals, which might be responsible for their streamlined body. © 2017 The Authors. Integrative Zoology published by International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and John Wiley & Sons Australia, Ltd.

An evolutionary yield function based on Barlat 2000 yield function for the superconducting niobium sheet

Science.gov (United States)

Darbandi, Payam; Pourboghrat, Farhang

2011-08-01

Superconducting radio frequency (SRF) niobium cavities are widely used in high-energy physics to accelerate particle beams in particle accelerators. The performance of SRF cavities is affected by the microstructure and purity of the niobium sheet, surface quality, geometry, etc. Following optimum strain paths in the forming of these cavities can significantly control these parameters. To select these strain paths, however, information about the mechanical behavior, microstructure, and formability of the niobium sheet is required. In this study the Barlat 2000 yield function has been used as a yield function for high purity niobium. Results from this study showed that, due to intrinsic behavior, it is necessary to evolve the anisotropic coefficients of Barlat's yield function in order to properly model the plastic behavior of the niobium sheet. The accuracy of the newly developed evolutionary yield function was verified by applying it to the modeling of the hydrostatic bulging of the niobium sheet. Also, in a separate attempt crystal plasticity finite element method was use to model the behavior of the polycrystalline niobium sheet with a particular initial texture.

An evolutionary yield function based on Barlat 2000 yield function for the superconducting niobium sheet

International Nuclear Information System (INIS)

Darbandi, Payam; Pourboghrat, Farhang

2011-01-01

Superconducting radio frequency (SRF) niobium cavities are widely used in high-energy physics to accelerate particle beams in particle accelerators. The performance of SRF cavities is affected by the microstructure and purity of the niobium sheet, surface quality, geometry, etc. Following optimum strain paths in the forming of these cavities can significantly control these parameters. To select these strain paths, however, information about the mechanical behavior, microstructure, and formability of the niobium sheet is required. In this study the Barlat 2000 yield function has been used as a yield function for high purity niobium. Results from this study showed that, due to intrinsic behavior, it is necessary to evolve the anisotropic coefficients of Barlat's yield function in order to properly model the plastic behavior of the niobium sheet. The accuracy of the newly developed evolutionary yield function was verified by applying it to the modeling of the hydrostatic bulging of the niobium sheet. Also, in a separate attempt crystal plasticity finite element method was use to model the behavior of the polycrystalline niobium sheet with a particular initial texture.

Freud: the first evolutionary psychologist?

Science.gov (United States)

LeCroy, D

2000-04-01

An evolutionary perspective on attachment theory and psychoanalytic theory brings these two fields together in interesting ways. Application of the evolutionary principle of parent-offspring conflict to attachment theory suggests that attachment styles represent context-sensitive, evolved (adaptive) behaviors. In addition, an emphasis on offspring counter-strategies to adult reproductive strategies leads to consideration of attachment styles as overt manifestations of psychodynamic mediating processes, including the defense mechanisms of repression and reaction formation.

Polimixina B: efeito dose e tempo dependente na nefrotoxicidade in vitro Polymyxin B: dose and time dependent nephrotoxicity effect in vitro

Directory of Open Access Journals (Sweden)

Luciana Barros de Moura Neiva

2013-01-01

Full Text Available OBJETIVO: Caracterizar a toxicidade da polimixina B (PmxB em células renais em dosagem e tempos diferentes. MÉTODOS: Células LLC-PK1, cultivadas em placas multiwell de 12 poços, foram divididas nos seguintes grupos: Controle (CTL - células mantidas em meio DMEM suplementado a 5%; G1 - células expostas à concentração de 75mM de PmxB; G2 - células expostas à concentração de 375mM de PmxB. Cada grupo foi avaliado nos tempos de 24, 48 e 72 horas quanto à viabilidade celular (Acridine Orange/Brometo de Etídio e apoptose (Hoechst 33342. RESULTADOS: Os dados demonstraram a viabilidade celular e a apoptose à exposição de três doses de PmxB em três intervalos de tempo, com um aumento significativo da toxicidade à elevação das doses e ao maior tempo de permanência no antibiótico para apoptose. CONCLUSÃO: A citotoxicidade pela PmxB, no modelo de cultivo celular, se mostrou tempo e dose dependente, aumentando com a maior exposição e maior dose de antibiótico.OBJECTIVE: To characterize the toxicity of polymyxin B (PmxB in renal cell in different dosage and times. METHODS: LLC-PK1 cells grown in 12 well multiwell plates were divided into the following groups: Control (CTL - cells maintained in DMEM supplemented with 5%; G1 - cells exposed to concentration of 75µM PmxB G2 - cells exposed to concentration of 375µM PmxB. Each group was assessed at 24,48 and 72 hours as for cell viability (Acridine orange/ethidium bromide and apoptosis (Hoechst 33342. RESULTS: The data demonstrate the cell viability and apoptosis exposure of three doses of PmxB in three time intervals, with a significant increase in toxicity to high doses and longer duration of stay in the antibiotic to apoptosis. CONCLUSION: Cytotoxicity by PmxB in cell culture model, showed to be time and dose dependent, increasing with increased exposure and higher dose of antibiotic.

A Hybrid Chaotic Quantum Evolutionary Algorithm

DEFF Research Database (Denmark)

Cai, Y.; Zhang, M.; Cai, H.

2010-01-01

A hybrid chaotic quantum evolutionary algorithm is proposed to reduce amount of computation, speed up convergence and restrain premature phenomena of quantum evolutionary algorithm. The proposed algorithm adopts the chaotic initialization method to generate initial population which will form a pe...... tests. The presented algorithm is applied to urban traffic signal timing optimization and the effect is satisfied....

A chaos-based evolutionary algorithm for general nonlinear programming problems

International Nuclear Information System (INIS)

El-Shorbagy, M.A.; Mousa, A.A.; Nasr, S.M.

2016-01-01

In this paper we present a chaos-based evolutionary algorithm (EA) for solving nonlinear programming problems named chaotic genetic algorithm (CGA). CGA integrates genetic algorithm (GA) and chaotic local search (CLS) strategy to accelerate the optimum seeking operation and to speed the convergence to the global solution. The integration of global search represented in genetic algorithm and CLS procedures should offer the advantages of both optimization methods while offsetting their disadvantages. By this way, it is intended to enhance the global convergence and to prevent to stick on a local solution. The inherent characteristics of chaos can enhance optimization algorithms by enabling it to escape from local solutions and increase the convergence to reach to the global solution. Twelve chaotic maps have been analyzed in the proposed approach. The simulation results using the set of CEC’2005 show that the application of chaotic mapping may be an effective strategy to improve the performances of EAs.

Evolutionary medicine: its scope, interest and potential.

Science.gov (United States)

Stearns, Stephen C

2012-11-07

This review is aimed at readers seeking an introductory overview, teaching courses and interested in visionary ideas. It first describes the range of topics covered by evolutionary medicine, which include human genetic variation, mismatches to modernity, reproductive medicine, degenerative disease, host-pathogen interactions and insights from comparisons with other species. It then discusses priorities for translational research, basic research and health management. Its conclusions are that evolutionary thinking should not displace other approaches to medical science, such as molecular medicine and cell and developmental biology, but that evolutionary insights can combine with and complement established approaches to reduce suffering and save lives. Because we are on the cusp of so much new research and innovative insights, it is hard to estimate how much impact evolutionary thinking will have on medicine, but it is already clear that its potential is enormous.

O Espaço-tempo Subjetivo do Indivíduo (ETSI

Directory of Open Access Journals (Sweden)

Celson D. Pereira

2010-07-01

Full Text Available Graças a seu Sistema Nervoso Central – SNC, um indivíduo se percebe no espaço e no tempo de seu ambiente. Mas, através de seus sentidos suas percepções são subjetivas. Por outro lado, sua mente é influenciada por agentes físicos e substâncias químicas que venha a ingerir. Estas constatações banais, do cotidiano, devem ser levadas em conta quando se empreende a elaboração de uma teoria relativa à mente. Os contextos em que se insere uma teoria dessa natureza envolvem antigas questões, ainda abertas, fazendo parte do denominado “Problema do Conhecimento”. Apresento um pequeno percurso histórico das reflexões de teóricos de diferentes especialidades sobre aquele problema. Proponho que hoje, participando daquele percurso, uma estrutura conceitual pode ser concebida, conjugando o indivíduo se percebendo em três instâncias: o ambiente físico, o ambiente sociocultural e seu próprio corpo, constituindo assim, suas características mentais, sua memória e sua história de vida. Trata-se de um super-espaço, que, independentemente, de ser, objetivamente, imaginável, ou não, referese a algo que existe. Tenho denominado esta estrutura por (ETSI. Como emergente do SNC ela pode ser estudada em contextos de investigações da neurociência contemporânea. Deste empreendimento, proponho que se podem originar bases científicas para psicologia.Palavras-chave: Interior do indivíduo; Neurociência; Complexidade; Espaço-tempo Subjetivo; Consciência.

When music tempo affects the temporal congruence between physical practice and motor imagery.

Science.gov (United States)

Debarnot, Ursula; Guillot, Aymeric

2014-06-01

When people listen to music, they hear beat and a metrical structure in the rhythm; these perceived patterns enable coordination with the music. A clear correspondence between the tempo of actual movement (e.g., walking) and that of music has been demonstrated, but whether similar coordination occurs during motor imagery is unknown. Twenty participants walked naturally for 8m, either physically or mentally, while listening to slow and fast music, or not listening to anything at all (control condition). Executed and imagined walking times were recorded to assess the temporal congruence between physical practice (PP) and motor imagery (MI). Results showed a difference when comparing slow and fast time conditions, but each of these durations did not differ from soundless condition times, hence showing that body movement may not necessarily change in order to synchronize with music. However, the main finding revealed that the ability to achieve temporal congruence between PP and MI times was altered when listening to either slow or fast music. These data suggest that when physical movement is modulated with respect to the musical tempo, the MI efficacy of the corresponding movement may be affected by the rhythm of the music. Practical applications in sport are discussed as athletes frequently listen to music before competing while they mentally practice their movements to be performed. Copyright © 2014 Elsevier B.V. All rights reserved.

Temporal knowledge and autobiographical memory: an evolutionary perspective

OpenAIRE

Skowronski, John J.; Sedikides, Constantine

2007-01-01

Section I: Philosophical issues 1. Evolutionary pyschology in the round , Robin Dunbar & Louise Barrett 2. The power of culture , Henry Plotkin 3. Evolution and psychology in philosophical perspective , Matteo Mameli 4. Niche construction, human behavioural ecology and evolutionary psychology , Kevin N Laland 5. Group level evolutionary processes , David Sloan Wilson Section II: The comparative Approach 6. Homologizing the mind , Drew Rendall, Hugh Nottman & John ...

Hypervalent iodine/TEMPO-mediated oxidation in flow systems: a fast and efficient protocol for alcohol oxidation

Directory of Open Access Journals (Sweden)

Nida Ambreen

2013-07-01

Full Text Available Hypervalent iodine(III/TEMPO-mediated oxidation of various aliphatic, aromatic and allylic alcohols to their corresponding carbonyl compounds was successfully achieved by using microreactor technology. This method can be used as an alternative for the oxidation of various alcohols achieving excellent yields and selectivities in significantly shortened reaction times.

“Der deutschen Jugend!” : The Newspaper Tempo and the Generational Discourse of the Weimar Republic

NARCIS (Netherlands)

Hung, J.B.|info:eu-repo/dai/nl/412768704

In the historiography of the Weimar Republic, the concept of ‘generations’ has often been drawn upon to explain the anti-democratic and reactionary attitude of the youth and its role in the demise of the first German democracy. Using the example of the newspaper Tempo, published 1928–33 with a

The ABCs of an evolutionary education science: The academic, behavioral, and cultural implications of an evolutionary approach to education theory and practice

Science.gov (United States)

Kauffman, Rick, Jr.

Calls for improving research-informed policy in education are everywhere. Yet, while there is an increasing trend towards science-based practice, there remains little agreement over which of the sciences to consult and how to organize a collective effort between them. What Education lacks is a general theoretical framework through which policies can be constructed, implemented, and assessed. This dissertation submits that evolutionary theory can provide a suitable framework for coordinating educational policies and practice, and can provide the entire field of education with a clearer sense of how to better manage the learning environment. This dissertation explores two broad paths that outline the conceptual foundations for an Evolutionary Education Science: "Teaching Evolution" and "Using Evolution to Teach." Chapter 1 introduces both of these themes. After describing why evolutionary science is best suited for organizing education research and practice, Chapter 1 proceeds to "teach" an overview of the "evolutionary toolkit"---the mechanisms and principles that underlie the modern evolutionary perspective. The chapter then employs the "toolkit" in examining education from an evolutionary perspective, outlining the evolutionary precepts that can guide theorizing and research in education, describing how educators can "use evolution to teach.". Chapters 2-4 expand on this second theme. Chapters 2 and 3 describe an education program for at-risk 9th and 10th grade students, the Regents Academy, designed entirely with evolutionary principles in mind. The program was rigorously assessed in a randomized control design and has demonstrated success at improving students' academic performance (Chapter 2) and social & behavioral development (Chapter 3). Chapter 4 examines current teaching strategies that underlie effective curriculum-instruction-assessment practices and proposes a framework for organizing successful, evidence-based strategies for neural

A compressão do tempo e a formação de novos hábitos alimentares : reveses e possibilidades

OpenAIRE

Magalhães, Elcio de Souza

2017-01-01

O aumento da quantidade de brasileiros com excesso de peso está relacionado com as alterações que estão ocorrendo no cotidiano do trabalhador e nos seus hábitos alimentares. Mudanças no mundo do trabalho, na mobilidade e no tempo livre do trabalhador têm estimulado a adoção de novos hábitos alimentares. O objetivo desta dissertação é investigar as relações existentes entre as mudanças que ocorreram nos hábitos alimentares com a compressão do tempo livre do trabalhador, bem como analisar e pro...

Testing the island effect on phenotypic diversification: insights from the Hemidactylus geckos of the Socotra Archipelago

Science.gov (United States)

Garcia-Porta, Joan; Šmíd, Jiří; Sol, Daniel; Fasola, Mauro; Carranza, Salvador

2016-04-01

Island colonization is often assumed to trigger extreme levels of phenotypic diversification. Yet, empirical evidence suggests that it does not always so. In this study we test this hypothesis using a completely sampled mainland-island system, the arid clade of Hemidactylus, a group of geckos mainly distributed across Africa, Arabia and the Socotra Archipelago. To such purpose, we generated a new molecular phylogeny of the group on which we mapped body size and head proportions. We then explored whether island and continental taxa shared the same morphospace and differed in their disparities and tempos of evolution. Insular species produced the most extreme sizes of the radiation, involving accelerated rates of evolution and higher disparities compared with most (but not all) of the continental groups. In contrast, head proportions exhibited constant evolutionary rates across the radiation and similar disparities in islands compared with the continent. These results, although generally consistent with the notion that islands promote high morphological disparity, reveal at the same time a complex scenario in which different traits may experience different evolutionary patterns in the same mainland-island system and continental groups do not always present low levels of morphological diversification compared to insular groups.

Evolutionary Game Theory: A Renaissance

Directory of Open Access Journals (Sweden)

Jonathan Newton

2018-05-01

Full Text Available Economic agents are not always rational or farsighted and can make decisions according to simple behavioral rules that vary according to situation and can be studied using the tools of evolutionary game theory. Furthermore, such behavioral rules are themselves subject to evolutionary forces. Paying particular attention to the work of young researchers, this essay surveys the progress made over the last decade towards understanding these phenomena, and discusses open research topics of importance to economics and the broader social sciences.

Evolutionary constrained optimization

CERN Document Server

Deb, Kalyanmoy

2015-01-01

This book makes available a self-contained collection of modern research addressing the general constrained optimization problems using evolutionary algorithms. Broadly the topics covered include constraint handling for single and multi-objective optimizations; penalty function based methodology; multi-objective based methodology; new constraint handling mechanism; hybrid methodology; scaling issues in constrained optimization; design of scalable test problems; parameter adaptation in constrained optimization; handling of integer, discrete and mix variables in addition to continuous variables; application of constraint handling techniques to real-world problems; and constrained optimization in dynamic environment. There is also a separate chapter on hybrid optimization, which is gaining lots of popularity nowadays due to its capability of bridging the gap between evolutionary and classical optimization. The material in the book is useful to researchers, novice, and experts alike. The book will also be useful...

Multi-agent evolutionary systems for the generation of complex virtual worlds

Directory of Open Access Journals (Sweden)

J. Kruse

2016-01-01

Full Text Available Modern films, games and virtual reality applications are dependent on convincing computer graphics. Highly complex models are a requirement for the successful delivery of many scenes and environments. While workflows such as rendering, compositing and animation have been streamlined to accommodate increasing demands, modelling complex models is still a laborious task. This paper introduces the computational benefits of an Interactive Genetic Algorithm (IGA to computer graphics modelling while compensating the effects of user fatigue, a common issue with Interactive Evolutionary Computation. An intelligent agent is used in conjunction with an IGA that offers the potential to reduce the effects of user fatigue by learning from the choices made by the human designer and directing the search accordingly. This workflow accelerates the layout and distribution of basic elements to form complex models. It captures the designer’s intent through interaction, and encourages playful discovery.

Evolutionary Computation and Its Applications in Neural and Fuzzy Systems

Directory of Open Access Journals (Sweden)

Biaobiao Zhang

2011-01-01

Full Text Available Neural networks and fuzzy systems are two soft-computing paradigms for system modelling. Adapting a neural or fuzzy system requires to solve two optimization problems: structural optimization and parametric optimization. Structural optimization is a discrete optimization problem which is very hard to solve using conventional optimization techniques. Parametric optimization can be solved using conventional optimization techniques, but the solution may be easily trapped at a bad local optimum. Evolutionary computation is a general-purpose stochastic global optimization approach under the universally accepted neo-Darwinian paradigm, which is a combination of the classical Darwinian evolutionary theory, the selectionism of Weismann, and the genetics of Mendel. Evolutionary algorithms are a major approach to adaptation and optimization. In this paper, we first introduce evolutionary algorithms with emphasis on genetic algorithms and evolutionary strategies. Other evolutionary algorithms such as genetic programming, evolutionary programming, particle swarm optimization, immune algorithm, and ant colony optimization are also described. Some topics pertaining to evolutionary algorithms are also discussed, and a comparison between evolutionary algorithms and simulated annealing is made. Finally, the application of EAs to the learning of neural networks as well as to the structural and parametric adaptations of fuzzy systems is also detailed.

The integration of Darwinism and evolutionary morphology: Alexej Nikolajevich Sewertzoff (1866-1936) and the developmental basis of evolutionary change.

Science.gov (United States)

Levit, George S; Hossfeld, Uwe; Olsson, Lennart

2004-07-15

The growth of evolutionary morphology in the late 19th and early 20th centuries was inspired by the work of Carl Gegenbaur (1826-1903) and his protégé and friend Ernst Haeckel (1834-1919). However, neither of them succeeded in creating and applying a strictly Darwinian (selectionist) methodology. This task was left to the next generation of evolutionary morphologists. In this paper we present a relatively unknown researcher, Alexej Nikolajevich Sewertzoff (1866-1936) who made important contributions towards a synthesis of Darwinism and evolutionary morphology. Copyright 2004 Wiley-Liss, Inc.

Evolutionary dynamics with fluctuating population sizes and strong mutualism

Science.gov (United States)

Chotibut, Thiparat; Nelson, David R.

2015-08-01

Game theory ideas provide a useful framework for studying evolutionary dynamics in a well-mixed environment. This approach, however, typically enforces a strictly fixed overall population size, deemphasizing natural growth processes. We study a competitive Lotka-Volterra model, with number fluctuations, that accounts for natural population growth and encompasses interaction scenarios typical of evolutionary games. We show that, in an appropriate limit, the model describes standard evolutionary games with both genetic drift and overall population size fluctuations. However, there are also regimes where a varying population size can strongly influence the evolutionary dynamics. We focus on the strong mutualism scenario and demonstrate that standard evolutionary game theory fails to describe our simulation results. We then analytically and numerically determine fixation probabilities as well as mean fixation times using matched asymptotic expansions, taking into account the population size degree of freedom. These results elucidate the interplay between population dynamics and evolutionary dynamics in well-mixed systems.

Evolutionary dynamics with fluctuating population sizes and strong mutualism.

Science.gov (United States)

Chotibut, Thiparat; Nelson, David R

2015-08-01

Game theory ideas provide a useful framework for studying evolutionary dynamics in a well-mixed environment. This approach, however, typically enforces a strictly fixed overall population size, deemphasizing natural growth processes. We study a competitive Lotka-Volterra model, with number fluctuations, that accounts for natural population growth and encompasses interaction scenarios typical of evolutionary games. We show that, in an appropriate limit, the model describes standard evolutionary games with both genetic drift and overall population size fluctuations. However, there are also regimes where a varying population size can strongly influence the evolutionary dynamics. We focus on the strong mutualism scenario and demonstrate that standard evolutionary game theory fails to describe our simulation results. We then analytically and numerically determine fixation probabilities as well as mean fixation times using matched asymptotic expansions, taking into account the population size degree of freedom. These results elucidate the interplay between population dynamics and evolutionary dynamics in well-mixed systems.

Islamic medicine and evolutionary medicine: a comparative analysis.

Science.gov (United States)

Saniotis, Arthur

2012-01-01

The advent of evolutionary medicine in the last two decades has provided new insights into the causes of human disease and possible preventative strategies. One of the strengths of evolutionary medicine is that it follows a multi-disciplinary approach. Such an approach is vital to future biomedicine as it enables for the infiltration of new ideas. Although evolutionary medicine uses Darwinian evolution as a heuristic for understanding human beings' susceptibility to disease, this is not necessarily in conflict with Islamic medicine. It should be noted that current evolutionary theory was first expounded by various Muslim scientists such as al-Jāḥiẓ, al-Ṭūsī, Ibn Khaldūn and Ibn Maskawayh centuries before Darwin and Wallace. In this way, evolution should not be viewed as being totally antithetical to Islam. This article provides a comparative overview of Islamic medicine and Evolutionary medicine as well as drawing points of comparison between the two approaches which enables their possible future integration.

Evolutionary engineering for industrial microbiology.

Science.gov (United States)

Vanee, Niti; Fisher, Adam B; Fong, Stephen S

2012-01-01

Superficially, evolutionary engineering is a paradoxical field that balances competing interests. In natural settings, evolution iteratively selects and enriches subpopulations that are best adapted to a particular ecological niche using random processes such as genetic mutation. In engineering desired approaches utilize rational prospective design to address targeted problems. When considering details of evolutionary and engineering processes, more commonality can be found. Engineering relies on detailed knowledge of the problem parameters and design properties in order to predict design outcomes that would be an optimized solution. When detailed knowledge of a system is lacking, engineers often employ algorithmic search strategies to identify empirical solutions. Evolution epitomizes this iterative optimization by continuously diversifying design options from a parental design, and then selecting the progeny designs that represent satisfactory solutions. In this chapter, the technique of applying the natural principles of evolution to engineer microbes for industrial applications is discussed to highlight the challenges and principles of evolutionary engineering.

Handbook of differential equations evolutionary equations

CERN Document Server

Dafermos, CM

2008-01-01

The material collected in this volume discusses the present as well as expected future directions of development of the field with particular emphasis on applications. The seven survey articles present different topics in Evolutionary PDE's, written by leading experts.- Review of new results in the area- Continuation of previous volumes in the handbook series covering Evolutionary PDEs- Written by leading experts

Thematic Interior at the Indischetafel Café As a Media for Forming Bandung Tempo Dulu’s Athmosphere

Directory of Open Access Journals (Sweden)

Tiara Isfiaty

2017-12-01

Full Text Available The interior elements designed in a specific theme are aimed to shape a character, a per- ception, and an atmosphere of spaces. In Bandung, culinary facilities that carry the theme of the old-style interior design of the Dutch East Indies are quite popular. This study aims to contribute guidance in creating the quality of space by applying the selection of decoration and furniture elements (moveable interior elements and the arrangement of walls, floors, and ceilings (unmoveable interior elements. This study applies a case study as a research method and a direct observation of the Indischetafel Café, while the analysis uses a descrip- tive analysis method. This study is to examine aspects of interior element arrangement in the Indischetafel Café in bringing the atmosphere of Bandung Tempo Dulu.   Keywords: thematic interior, interior elements, space atmosphere, Bandung Tempo Dulu

Differential effects of type of keyboard playing task and tempo on surface EMG amplitudes of forearm muscles

Directory of Open Access Journals (Sweden)

Hyun Ju eChong

2015-09-01

Full Text Available Despite increasing interest in keyboard playing as a strategy for repetitive finger exercises in fine motor skill development and hand rehabilitation, comparative analysis of task-specific finger movements relevant to keyboard playing has been less extensive. This study examined whether there were differences in surface EMG activity levels of forearm muscles associated with different keyboard playing tasks. Results demonstrated higher muscle activity with sequential keyboard playing in a random pattern compared to individuated playing or sequential playing in a successive pattern. Also, the speed of finger movements was found as a factor that affect muscle activity levels, demonstrating that faster tempo elicited significantly greater muscle activity than self-paced tempo. The results inform our understanding of the type of finger movements involved in different types of keyboard playing at different tempi so as to consider the efficacy and fatigue level of keyboard playing as an intervention for amateur pianists or individuals with impaired fine motor skills.

Differential effects of type of keyboard playing task and tempo on surface EMG amplitudes of forearm muscles

Science.gov (United States)

Chong, Hyun Ju; Kim, Soo Ji; Yoo, Ga Eul

2015-01-01

Despite increasing interest in keyboard playing as a strategy for repetitive finger exercises in fine motor skill development and hand rehabilitation, comparative analysis of task-specific finger movements relevant to keyboard playing has been less extensive. This study examined, whether there were differences in surface EMG activity levels of forearm muscles associated with different keyboard playing tasks. Results demonstrated higher muscle activity with sequential keyboard playing in a random pattern compared to individuated playing or sequential playing in a successive pattern. Also, the speed of finger movements was found as a factor that affect muscle activity levels, demonstrating that faster tempo elicited significantly greater muscle activity than self-paced tempo. The results inform our understanding of the type of finger movements involved in different types of keyboard playing at different tempi. This helps to consider the efficacy and fatigue level of keyboard playing tasks when being used as an intervention for amateur pianists or individuals with impaired fine motor skills. PMID:26388798

Evolutionary algorithms for mobile ad hoc networks

CERN Document Server

Dorronsoro, Bernabé; Danoy, Grégoire; Pigné, Yoann; Bouvry, Pascal

2014-01-01

Describes how evolutionary algorithms (EAs) can be used to identify, model, and minimize day-to-day problems that arise for researchers in optimization and mobile networking. Mobile ad hoc networks (MANETs), vehicular networks (VANETs), sensor networks (SNs), and hybrid networks—each of these require a designer’s keen sense and knowledge of evolutionary algorithms in order to help with the common issues that plague professionals involved in optimization and mobile networking. This book introduces readers to both mobile ad hoc networks and evolutionary algorithms, presenting basic concepts as well as detailed descriptions of each. It demonstrates how metaheuristics and evolutionary algorithms (EAs) can be used to help provide low-cost operations in the optimization process—allowing designers to put some “intelligence” or sophistication into the design. It also offers efficient and accurate information on dissemination algorithms topology management, and mobility models to address challenges in the ...

Evolutionary change in physiological phenotypes along the human lineage.

Science.gov (United States)

Vining, Alexander Q; Nunn, Charles L

2016-01-01

Research in evolutionary medicine provides many examples of how evolution has shaped human susceptibility to disease. Traits undergoing rapid evolutionary change may result in associated costs or reduce the energy available to other traits. We hypothesize that humans have experienced more such changes than other primates as a result of major evolutionary change along the human lineage. We investigated 41 physiological traits across 50 primate species to identify traits that have undergone marked evolutionary change along the human lineage. We analysed the data using two Bayesian phylogenetic comparative methods. One approach models trait covariation in non-human primates and predicts human phenotypes to identify whether humans are evolutionary outliers. The other approach models adaptive shifts under an Ornstein-Uhlenbeck model of evolution to assess whether inferred shifts are more common on the human branch than on other primate lineages. We identified four traits with strong evidence for an evolutionary increase on the human lineage (amylase, haematocrit, phosphorus and monocytes) and one trait with strong evidence for decrease (neutrophilic bands). Humans exhibited more cases of distinct evolutionary change than other primates. Human physiology has undergone increased evolutionary change compared to other primates. Long distance running may have contributed to increases in haematocrit and mean corpuscular haemoglobin concentration, while dietary changes are likely related to increases in amylase. In accordance with the pathogen load hypothesis, human monocyte levels were increased, but many other immune-related measures were not. Determining the mechanisms underlying conspicuous evolutionary change in these traits may provide new insights into human disease. The Author(s) 2016. Published by Oxford University Press on behalf of the Foundation for Evolution, Medicine, and Public Health.

Effect of music tempo on task performance.

Science.gov (United States)

Mayfield, C; Moss, S

1989-12-01

Two studies were conducted to evaluate the effect of music tempo on task performance. In Study 1, 44 undergraduate business students were asked to be "workers" in a stock market project by collecting closing stock prices and calculating the percentage of change in the price from week to week. Subjects were randomly divided into groups such that they either listened to fast-paced music while they worked, to slow-paced music, or to no music. Analyses of variance and covariance were conducted on both the quantity and quality of the subjects' work, using music listening habits as a covariate. There were no differences in either the quantity or quality of the work produced by the groups. There were some methodological concerns regarding Study 1, so a second study was conducted. The 70 undergraduate business students in Study 2 completed the same task under the same music conditions as in Study 1. Analyses of variance indicated women performed significantly better than men, performance was significantly higher in the rock condition than in the heartbeat condition, and subjects in the rock condition had a significantly higher perceived level of distraction by the music.

Human genomic disease variants: a neutral evolutionary explanation.

Science.gov (United States)

Dudley, Joel T; Kim, Yuseob; Liu, Li; Markov, Glenn J; Gerold, Kristyn; Chen, Rong; Butte, Atul J; Kumar, Sudhir

2012-08-01

Many perspectives on the role of evolution in human health include nonempirical assumptions concerning the adaptive evolutionary origins of human diseases. Evolutionary analyses of the increasing wealth of clinical and population genomic data have begun to challenge these presumptions. In order to systematically evaluate such claims, the time has come to build a common framework for an empirical and intellectual unification of evolution and modern medicine. We review the emerging evidence and provide a supporting conceptual framework that establishes the classical neutral theory of molecular evolution (NTME) as the basis for evaluating disease- associated genomic variations in health and medicine. For over a decade, the NTME has already explained the origins and distribution of variants implicated in diseases and has illuminated the power of evolutionary thinking in genomic medicine. We suggest that a majority of disease variants in modern populations will have neutral evolutionary origins (previously neutral), with a relatively smaller fraction exhibiting adaptive evolutionary origins (previously adaptive). This pattern is expected to hold true for common as well as rare disease variants. Ultimately, a neutral evolutionary perspective will provide medicine with an informative and actionable framework that enables objective clinical assessment beyond convenient tendencies to invoke past adaptive events in human history as a root cause of human disease.

Comparing Evolutionary Strategies on a Biobjective Cultural Algorithm

Directory of Open Access Journals (Sweden)

Carolina Lagos

2014-01-01

Full Text Available Evolutionary algorithms have been widely used to solve large and complex optimisation problems. Cultural algorithms (CAs are evolutionary algorithms that have been used to solve both single and, to a less extent, multiobjective optimisation problems. In order to solve these optimisation problems, CAs make use of different strategies such as normative knowledge, historical knowledge, circumstantial knowledge, and among others. In this paper we present a comparison among CAs that make use of different evolutionary strategies; the first one implements a historical knowledge, the second one considers a circumstantial knowledge, and the third one implements a normative knowledge. These CAs are applied on a biobjective uncapacitated facility location problem (BOUFLP, the biobjective version of the well-known uncapacitated facility location problem. To the best of our knowledge, only few articles have applied evolutionary multiobjective algorithms on the BOUFLP and none of those has focused on the impact of the evolutionary strategy on the algorithm performance. Our biobjective cultural algorithm, called BOCA, obtains important improvements when compared to other well-known evolutionary biobjective optimisation algorithms such as PAES and NSGA-II. The conflicting objective functions considered in this study are cost minimisation and coverage maximisation. Solutions obtained by each algorithm are compared using a hypervolume S metric.

The Evolutionary Origins of Hierarchy.

Science.gov (United States)

Mengistu, Henok; Huizinga, Joost; Mouret, Jean-Baptiste; Clune, Jeff

2016-06-01

Hierarchical organization-the recursive composition of sub-modules-is ubiquitous in biological networks, including neural, metabolic, ecological, and genetic regulatory networks, and in human-made systems, such as large organizations and the Internet. To date, most research on hierarchy in networks has been limited to quantifying this property. However, an open, important question in evolutionary biology is why hierarchical organization evolves in the first place. It has recently been shown that modularity evolves because of the presence of a cost for network connections. Here we investigate whether such connection costs also tend to cause a hierarchical organization of such modules. In computational simulations, we find that networks without a connection cost do not evolve to be hierarchical, even when the task has a hierarchical structure. However, with a connection cost, networks evolve to be both modular and hierarchical, and these networks exhibit higher overall performance and evolvability (i.e. faster adaptation to new environments). Additional analyses confirm that hierarchy independently improves adaptability after controlling for modularity. Overall, our results suggest that the same force-the cost of connections-promotes the evolution of both hierarchy and modularity, and that these properties are important drivers of network performance and adaptability. In addition to shedding light on the emergence of hierarchy across the many domains in which it appears, these findings will also accelerate future research into evolving more complex, intelligent computational brains in the fields of artificial intelligence and robotics.

The Evolutionary Origins of Hierarchy

Science.gov (United States)

Huizinga, Joost; Clune, Jeff

2016-01-01

Hierarchical organization—the recursive composition of sub-modules—is ubiquitous in biological networks, including neural, metabolic, ecological, and genetic regulatory networks, and in human-made systems, such as large organizations and the Internet. To date, most research on hierarchy in networks has been limited to quantifying this property. However, an open, important question in evolutionary biology is why hierarchical organization evolves in the first place. It has recently been shown that modularity evolves because of the presence of a cost for network connections. Here we investigate whether such connection costs also tend to cause a hierarchical organization of such modules. In computational simulations, we find that networks without a connection cost do not evolve to be hierarchical, even when the task has a hierarchical structure. However, with a connection cost, networks evolve to be both modular and hierarchical, and these networks exhibit higher overall performance and evolvability (i.e. faster adaptation to new environments). Additional analyses confirm that hierarchy independently improves adaptability after controlling for modularity. Overall, our results suggest that the same force–the cost of connections–promotes the evolution of both hierarchy and modularity, and that these properties are important drivers of network performance and adaptability. In addition to shedding light on the emergence of hierarchy across the many domains in which it appears, these findings will also accelerate future research into evolving more complex, intelligent computational brains in the fields of artificial intelligence and robotics. PMID:27280881

The Evolutionary Origins of Hierarchy.

Directory of Open Access Journals (Sweden)

Henok Mengistu

2016-06-01

Full Text Available Hierarchical organization-the recursive composition of sub-modules-is ubiquitous in biological networks, including neural, metabolic, ecological, and genetic regulatory networks, and in human-made systems, such as large organizations and the Internet. To date, most research on hierarchy in networks has been limited to quantifying this property. However, an open, important question in evolutionary biology is why hierarchical organization evolves in the first place. It has recently been shown that modularity evolves because of the presence of a cost for network connections. Here we investigate whether such connection costs also tend to cause a hierarchical organization of such modules. In computational simulations, we find that networks without a connection cost do not evolve to be hierarchical, even when the task has a hierarchical structure. However, with a connection cost, networks evolve to be both modular and hierarchical, and these networks exhibit higher overall performance and evolvability (i.e. faster adaptation to new environments. Additional analyses confirm that hierarchy independently improves adaptability after controlling for modularity. Overall, our results suggest that the same force-the cost of connections-promotes the evolution of both hierarchy and modularity, and that these properties are important drivers of network performance and adaptability. In addition to shedding light on the emergence of hierarchy across the many domains in which it appears, these findings will also accelerate future research into evolving more complex, intelligent computational brains in the fields of artificial intelligence and robotics.

An Evolutionary Psychology Approach to Consumer Choice

Directory of Open Access Journals (Sweden)

ZURINA BT MOHAIDIN

2013-07-01

Full Text Available Human behaviour can be explained not only through experience and environments but also by incorporating evolutionary explanation. Consumer behaviour could not be understood accurately without infusing Darwinian evolutionary theory which has contributed in the knowledge of human nature. Evolutionary psychology revolves around the human’s evolved mental and the impact on human’s traits and behaviour where the influence of the environment to our genes would determine our individual behaviour and traits, resulting in variation among us. Foraging which is a part of behavioural ecology involves many sequences or repetitions of animals’ activities and decision making which is useful to relate these patterns of activities to the decisions made in human consumption. The aim of this research is to investigate the similarities of human consumption and ecological behaviour by employing interpretative and comparative approach. It is hoped that by applying the evolutionary theory in explaining consumer choice, this study is able to contribute to the development of behavioural ecology in human consumption. The analysis of the data is done aggregately for 200 consumers and individually for 20 consumers, who have purchased four product categories over a year. This study concludes that the theories of evolutionary psychology can fit to the consumers’ buying behaviour implicating its usefulness in explaining the consumers’ choice.

Effect of the addition of two superoxide dismutase analogues (Tempo and Tempol) to alpaca semen extender for cryopreservation.

Science.gov (United States)

Santiani, Alexei; Acosta, Alexei Santiani; Evangelista, Shirley; Vargas, Shirley Evangelista; Valdivia, Martha; Cuya, Martha Valdivia; Risopatrón, Jennie; González, Jennie Risopatrón; Sánchez, Raúl; Gutiérrez, Raúl Sánchez

2013-03-15

The main objective was to study the effects, on sperm function, of the addition of two superoxide dismutase (SOD) analogues (Tempo and Tempol) to alpaca semen extender for cryopreservation. Twelve alpaca semen samples were collected using an artificial vagina and then diluted at a 1:3 ratio in an extender based on skim milk, egg yolk, and fructose. Each semen sample was divided into three equal parts to form the following groups: control, Tempo (1 mM), and Tempol (1 mM). Groups were cooled to 5 °C in 90 minutes (-1 °C in 3 minutes); when samples reached approximately 10 °C, SOD analogues were added to the respective groups. At 5 °C, ethylene glycol (final concentration, 0.1 M) was added to each group. After 30 minutes at 5 °C, samples were loaded in 0.25 mL plastic straws, placed in liquid nitrogen vapor for 15 minutes, and then plunged. Percentages of sperm motility, functional sperm membrane integrity, and viable sperm with intact acrosomes were evaluated before and after freeze-thaw using visual analysis, the hypoosmotic swelling test, and the double-stain trypan blue/giemsa technique, respectively. The Terminal deoxymucleotidyl transferase dUTP Nick End Labeling assay was performed for evaluation of sperm DNA fragmentation of frozen-thawed sperm. Sperm motility was higher (P < 0.05) in the Tempol and Tempo groups than in the control group (mean, 22.1%, 19.7%, and 11.2%, respectively), with similar results for functional sperm membrane integrity. Additionally, DNA fragmentation was lower (P < 0.05) in the Tempol group (16.7%) than in the control group (38.8%). Viable sperm with intact acrosomes were not affected by the use of SOD analogues. There was a negative correlation (r = -0.58) between DNA fragmentation of alpaca sperm and sperm motility after freeze-thawing, but DNA damage was neither related to functional membrane integrity nor viable sperm with intact acrosomes. We concluded that DNA fragmentation and loss of motility during cryopreservation of

The four cornerstones of Evolutionary Toxicology.

Science.gov (United States)

Bickham, John W

2011-05-01

Evolutionary Toxicology is the study of the effects of chemical pollutants on the genetics of natural populations. Research in Evolutionary Toxicology uses experimental designs familiar to the ecotoxicologist with matched reference and contaminated sites and the selection of sentinel species. It uses the methods of molecular genetics and population genetics, and is based on the theories and concepts of evolutionary biology and conservation genetics. Although it is a relatively young field, interest is rapidly growing among ecotoxicologists and more and more field studies and even controlled laboratory experiments are appearing in the literature. A number of population genetic impacts have been observed in organisms exposed to pollutants which I refer to here as the four cornerstones of Evolutionary Toxicology. These include (1) genome-wide changes in genetic diversity, (2) changes in allelic or genotypic frequencies caused by contaminant-induced selection acting at survivorship loci, (3) changes in dispersal patterns or gene flow which alter the genetic relationships among populations, and (4) changes in allelic or genotypic frequencies caused by increased mutation rates. It is concluded that population genetic impacts of pollution exposure are emergent effects that are not necessarily predictable from the mode of toxicity of the pollutant. Thus, to attribute an effect to a particular contaminant requires a careful experimental design which includes selection of appropriate reference sites, detailed chemistry analyses of environmental samples and tissues, and the use of appropriate biomarkers to establish exposure and effect. This paper describes the field of Evolutionary Toxicology and discusses relevant field studies and their findings. © Springer Science+Business Media, LLC 2011

Applied evolutionary economics and economic geography

OpenAIRE

Peter Sunley

2008-01-01

Applied Evolutionary Economics and Economic Geography aims to further advance empirical methodologies in evolutionary economics, with a special emphasis on geography and firm location. It does so by bringing together a select group of leading scholars including economists, geographers and sociologists, all of whom share an interest in explaining the uneven distribution of economic activities in space and the historical processes that have produced these patterns.

Transiently disordered tails accelerate folding of globular proteins.

Science.gov (United States)

Mallik, Saurav; Ray, Tanaya; Kundu, Sudip

2017-07-01

Numerous biological proteins exhibit intrinsic disorder at their termini, which are associated with multifarious functional roles. Here, we show the surprising result that an increased percentage of terminal short transiently disordered regions with enhanced flexibility (TstDREF) is associated with accelerated folding rates of globular proteins. Evolutionary conservation of predicted disorder at TstDREFs and drastic alteration of folding rates upon point-mutations suggest critical regulatory role(s) of TstDREFs in shaping the folding kinetics. TstDREFs are associated with long-range intramolecular interactions and the percentage of native secondary structural elements physically contacted by TstDREFs exhibit another surprising positive correlation with folding kinetics. These results allow us to infer probable molecular mechanisms behind the TstDREF-mediated regulation of folding kinetics that challenge protein biochemists to assess by direct experimental testing. © 2017 Federation of European Biochemical Societies.

On economic applications of evolutionary game theory

OpenAIRE

Daniel Friedman

1998-01-01

Evolutionary games have considerable unrealized potential for modeling substantive economic issues. They promise richer predictions than orthodox game models but often require more extensive specifications. This paper exposits the specification of evolutionary game models and classifies the possible asymptotic behavior for one and two dimensional models.

On the Evolutionary Stability of Bargaining Inefficiency

DEFF Research Database (Denmark)

Poulsen, Anders

This paper investigates whether 'tough' bargaining behavior, which gives rise to inefficiency, can be evolutionary stable. We show that in a two-stage Nash Demand Game tough behavior survives. Indeed, almost all the surplus may be wasted. We also study the Ultimatum Game. Here evolutionary select...

Evolutionary Robotics: What, Why, and Where to

Directory of Open Access Journals (Sweden)

Stephane eDoncieux

2015-03-01

Full Text Available Evolutionary robotics applies the selection, variation, and heredity principles of natural evolution to the design of robots with embodied intelligence. It can be considered as a subfield of robotics that aims to create more robust and adaptive robots. A pivotal feature of the evolutionary approach is that it considers the whole robot at once, and enables the exploitation of robot features in a holistic manner. Evolutionary robotics can also be seen as an innovative approach to the study of evolution based on a new kind of experimentalism. The use of robots as a substrate can help address questions that are difficult, if not impossible, to investigate through computer simulations or biological studies. In this paper we consider the main achievements of evolutionary robotics, focusing particularly on its contributions to both engineering and biology. We briefly elaborate on methodological issues, review some of the most interesting findings, and discuss important open issues and promising avenues for future work.

Evolutionary ethics from Darwin to Moore.

Science.gov (United States)

Allhoff, Fritz

2003-01-01

Evolutionary ethics has a long history, dating all the way back to Charles Darwin. Almost immediately after the publication of the Origin, an immense interest arose in the moral implications of Darwinism and whether the truth of Darwinism would undermine traditional ethics. Though the biological thesis was certainly exciting, nobody suspected that the impact of the Origin would be confined to the scientific arena. As one historian wrote, 'whether or not ancient populations of armadillos were transformed into the species that currently inhabit the new world was certainly a topic about which zoologists could disagree. But it was in discussing the broader implications of the theory...that tempers flared and statements were made which could transform what otherwise would have been a quiet scholarly meeting into a social scandal' (Farber 1994, 22). Some resistance to the biological thesis of Darwinism sprung from the thought that it was incompatible with traditional morality and, since one of them had to go, many thought that Darwinism should be rejected. However, some people did realize that a secular ethics was possible so, even if Darwinism did undermine traditional religious beliefs, it need not have any effects on moral thought. Before I begin my discussion of evolutionary ethics from Darwin to Moore, I would like to make some more general remarks about its development. There are three key events during this history of evolutionary ethics. First, Charles Darwin published On the Origin of the Species (Darwin 1859). Since one did not have a fully developed theory of evolution until 1859, there exists little work on evolutionary ethics until then. Shortly thereafter, Herbert Spencer (1898) penned the first systematic theory of evolutionary ethics, which was promptly attacked by T.H. Huxley (Huxley 1894). Second, at about the turn of the century, moral philosophers entered the fray and attempted to demonstrate logical errors in Spencer's work; such errors were alluded

[Charles Darwin and the problem of evolutionary progress].

Science.gov (United States)

Iordanskiĭ, N N

2010-01-01

According to Ch. Darwin's evolutionary theory, evolutionary progress (interpreted as morpho-physiological progress or arogenesis in recent terminology) is one of logical results of natural selection. At the same time, natural selection does not hold any factors especially promoting evolutionary progress. Darwin emphasized that the pattern of evolutionary changes depends on organism nature more than on the pattern of environment changes. Arogenesis specificity is determined by organization of rigorous biological systems - integral organisms. Onward progressive development is determined by fundamental features of living organisms: metabolism and homeostasis. The concept of social Darwinism differs fundamentally from Darwin's ideas about the most important role of social instincts in progress of mankind. Competition and selection play secondary role in socio-cultural progress of human society.

Improving the Adaptability of Simulated Evolutionary Swarm Robots in Dynamically Changing Environments

Science.gov (United States)

Yao, Yao; Marchal, Kathleen; Van de Peer, Yves

2014-01-01

One of the important challenges in the field of evolutionary robotics is the development of systems that can adapt to a changing environment. However, the ability to adapt to unknown and fluctuating environments is not straightforward. Here, we explore the adaptive potential of simulated swarm robots that contain a genomic encoding of a bio-inspired gene regulatory network (GRN). An artificial genome is combined with a flexible agent-based system, representing the activated part of the regulatory network that transduces environmental cues into phenotypic behaviour. Using an artificial life simulation framework that mimics a dynamically changing environment, we show that separating the static from the conditionally active part of the network contributes to a better adaptive behaviour. Furthermore, in contrast with most hitherto developed ANN-based systems that need to re-optimize their complete controller network from scratch each time they are subjected to novel conditions, our system uses its genome to store GRNs whose performance was optimized under a particular environmental condition for a sufficiently long time. When subjected to a new environment, the previous condition-specific GRN might become inactivated, but remains present. This ability to store ‘good behaviour’ and to disconnect it from the novel rewiring that is essential under a new condition allows faster re-adaptation if any of the previously observed environmental conditions is reencountered. As we show here, applying these evolutionary-based principles leads to accelerated and improved adaptive evolution in a non-stable environment. PMID:24599485

Improving the adaptability of simulated evolutionary swarm robots in dynamically changing environments.

Directory of Open Access Journals (Sweden)

Yao Yao

Full Text Available One of the important challenges in the field of evolutionary robotics is the development of systems that can adapt to a changing environment. However, the ability to adapt to unknown and fluctuating environments is not straightforward. Here, we explore the adaptive potential of simulated swarm robots that contain a genomic encoding of a bio-inspired gene regulatory network (GRN. An artificial genome is combined with a flexible agent-based system, representing the activated part of the regulatory network that transduces environmental cues into phenotypic behaviour. Using an artificial life simulation framework that mimics a dynamically changing environment, we show that separating the static from the conditionally active part of the network contributes to a better adaptive behaviour. Furthermore, in contrast with most hitherto developed ANN-based systems that need to re-optimize their complete controller network from scratch each time they are subjected to novel conditions, our system uses its genome to store GRNs whose performance was optimized under a particular environmental condition for a sufficiently long time. When subjected to a new environment, the previous condition-specific GRN might become inactivated, but remains present. This ability to store 'good behaviour' and to disconnect it from the novel rewiring that is essential under a new condition allows faster re-adaptation if any of the previously observed environmental conditions is reencountered. As we show here, applying these evolutionary-based principles leads to accelerated and improved adaptive evolution in a non-stable environment.

Influência do tempo máximo de mistura e transporte especificado pela ABNT NBR 7212:2012 na resistência a compressão de concretos usinados

Directory of Open Access Journals (Sweden)

Lucas da Silva Barboza

2017-12-01

Full Text Available A ABNT NBR 7212:2012, estipula o tempo máximo para a entrega e lançamento total do concreto em 150 minutos; porém, na prática por vários fatores como logística, congestionamento, problemas com caminhão, entre outros, o tempo limite é extrapolado. Geralmente, por falta de conhecimento técnico, adiciona-se água ao concreto como forma de alterar sua consistência dando a trabalhabilidade desejada, a fim de facilitar o lançamento e obter adequado acabamento do concreto. Este artigo tem como objetivo principal avaliar, em situação real, a variação da consistência do concreto e a percentagem de perda de sua resistência à compressão, no decorrer de um período de 6 horas após o início da hidratação do cimento Portland, ocasionado pela adição de água para correção da fluidez perdida. Os resultados, como esperados, mostram uma redução na trabalhabilidade do concreto com o passar do tempo, obtendo-se, já nas 2 primeiras horas de mistura, um abatimento médio de 105 mm, ou seja, 11,54% inferior ao abatimento médio encontrado no tempo T(0 de 118,7 mm. A correção do abatimento do concreto através da adição de água, no tempo T(6, resultou no aumento do fator água/cimento ocasionando perda de 57,47% de resistência à compressão, quando comparada com as amostras do tempo T(0, aos 28 dias. As soluções oferecidas para este problema são: instruir os funcionários relacionados à concretagem; melhora da logística e utilização de aditivos, garantindo a resistência à compressão prevista na dosagem do concreto.

Evolutionary adaptations: theoretical and practical implications for visual ergonomics.

Science.gov (United States)

Fostervold, Knut Inge; Watten, Reidulf G; Volden, Frode

2014-01-01

The literature discussing visual ergonomics often mention that human vision is adapted to light emitted by the sun. However, theoretical and practical implications of this viewpoint is seldom discussed or taken into account. The paper discusses some of the main theoretical implications of an evolutionary approach to visual ergonomics. Based on interactional theory and ideas from ecological psychology an evolutionary stress model is proposed as a theoretical framework for future research in ergonomics and human factors. The model stresses the importance of developing work environments that fits with our evolutionary adaptations. In accordance with evolutionary psychology, the environment of evolutionary adaptedness (EEA) and evolutionarily-novel environments (EN) are used as key concepts. Using work with visual display units (VDU) as an example, the paper discusses how this knowledge can be utilized in an ergonomic analysis of risk factors in the work environment. The paper emphasises the importance of incorporating evolutionary theory in the field of ergonomics. Further, the paper encourages scientific practices that further our understanding of any phenomena beyond the borders of traditional proximal explanations.

Evolutionary Biology Today

Indian Academy of Sciences (India)

Hindi and English. Port 1. Resonance, Vo1.7 ... they use. Of course, many evolutionary biologists do work with fossils or DNA, or both, but there are also large numbers of ... The first major division that I like to make is between studies focussed ...

Efeitos tempo, parturição e quantum no Brasil: indicadores de período e evidências empíricas

Directory of Open Access Journals (Sweden)

Adriana de Miranda-Ribeiro

2013-06-01

Full Text Available O presente artigo tem como objetivo estimar e comparar diferentes indicadores de fecundidade de período, com enfoque naqueles que corrigem distorções causadas na taxa de fecundidade total (TFT observada em determinado período, a fim de criar e avaliar novas possibilidades de análise da fecundidade no Brasil. São apresentadas séries de TFT, TFT PPR, PATFR, PATFRajustada (K-O, PDTFR e PADTFR, bem como as séries históricas dos efeitos tempo e parturição e da idade média da fecundidade. Foram utilizados os bancos de dados sobre histórias de nascimentos, obtidos a partir das edições de 1980, 1991 e 2000 do Censo Demográfico brasileiro. Os resultados mostram que, no Brasil, a transição da fecundidade foi acompanhada, durante praticamente todo o período de análise, por um efeito tempo negativo e um efeito parturição positivo, que atuaram no sentido de inflar a fecundidade observada. No futuro próximo, a fecundidade observada no Brasil deverá ser diminuída, principalmente pela ação do efeito tempo positivo.

Influence of varied tempo music on wheelchair mechanical efficiency following 3-week practice.

Science.gov (United States)

Goosey-Tolfrey, V L; West, M; Lenton, J P; Tolfrey, K

2011-02-01

The purpose of this study was to analyse adaptations in propulsion technique and gross efficiency in novice able-bodied subjects during the initial phase of learning hand-rim wheelchair propulsion to music. 22 able bodied participants performed wheelchair propulsion (1.1 m·s(-1)) followed by a VO(2) peak test on a wheelchair ergometer. Push frequency, gross efficiency (GE), heart rate, rating of perceived exertion and propulsion technique variables (force application and temporal characteristics) were recorded. Participants were then assigned to a 3-wk practice period listening to i) 125 beats·min(-1) tempo music (LOW); ii) 170 beats·min(-1) tempo music (HIGH); or iii) a control group (CON). Following practice, all participants repeated the pre-testing protocol whilst force application data was collected in practice trials 1 and 9. After accounting for the pre-practice differences in GE (using ANCOVA), GE was higher in LOW compared with CON (P=0.038; 6.6 vs. 6.1% respectively). The differences between CON vs. HIGH and LOW vs. HIGH (P=0.830; P=0.188) were trivial suggesting that only LOW experienced an increase in GE. Practice had a favourable effect on the perceptions of effort, work per cycle, push and cycle time in contrast to the CON group. The use of music in a rehabilitation setting warrants further investigation. © Georg Thieme Verlag KG Stuttgart · New York.

The evolutionary rate dynamically tracks changes in HIV-1 epidemics

Energy Technology Data Exchange (ETDEWEB)

Maljkovic-berry, Irina [Los Alamos National Laboratory; Athreya, Gayathri [Los Alamos National Laboratory; Daniels, Marcus [Los Alamos National Laboratory; Bruno, William [Los Alamos National Laboratory; Korber, Bette [Los Alamos National Laboratory; Kuiken, Carla [Los Alamos National Laboratory; Ribeiro, Ruy M [Los Alamos National Laboratory

2009-01-01

Large-sequence datasets provide an opportunity to investigate the dynamics of pathogen epidemics. Thus, a fast method to estimate the evolutionary rate from large and numerous phylogenetic trees becomes necessary. Based on minimizing tip height variances, we optimize the root in a given phylogenetic tree to estimate the most homogenous evolutionary rate between samples from at least two different time points. Simulations showed that the method had no bias in the estimation of evolutionary rates and that it was robust to tree rooting and topological errors. We show that the evolutionary rates of HIV-1 subtype B and C epidemics have changed over time, with the rate of evolution inversely correlated to the rate of virus spread. For subtype B, the evolutionary rate slowed down and tracked the start of the HAART era in 1996. Subtype C in Ethiopia showed an increase in the evolutionary rate when the prevalence increase markedly slowed down in 1995. Thus, we show that the evolutionary rate of HIV-1 on the population level dynamically tracks epidemic events.

The First Joke: Exploring the Evolutionary Origins of Humor

Directory of Open Access Journals (Sweden)

Joseph Polimeni

2006-01-01

Full Text Available Humor is a complex cognitive function which often leads to laughter. Contemporary humor theorists have begun to formulate hypotheses outlining the possible innate cognitive structures underlying humor. Humor's conspicuous presence in the behavioral repertoire of humankind invites adaptive explanations. This article explores the possible adaptive features of humor and ponders its evolutionary path through hominid history. Current humor theories and previous evolutionary ideas on humor are reviewed. In addition, scientific fields germane to the evolutionary study of humor are examined: animal models, genetics, children's humor, humor in pathological conditions, neurobiology, humor in traditional societies and cognitive archeology. Candidate selection pressures and associated evolutionary mechanisms are considered. The authors conclude that several evolutionary-related topics such as the origins of language, cognition underlying spiritual feelings, hominid group size, and primate teasing could have special relevance to the origins of humor.

Predicting loss of evolutionary history: Where are we?

Science.gov (United States)

Veron, Simon; Davies, T Jonathan; Cadotte, Marc W; Clergeau, Philippe; Pavoine, Sandrine

2017-02-01

The Earth's evolutionary history is threatened by species loss in the current sixth mass extinction event in Earth's history. Such extinction events not only eliminate species but also their unique evolutionary histories. Here we review the expected loss of Earth's evolutionary history quantified by phylogenetic diversity (PD) and evolutionary distinctiveness (ED) at risk. Due to the general paucity of data, global evolutionary history losses have been predicted for only a few groups, such as mammals, birds, amphibians, plants, corals and fishes. Among these groups, there is now empirical support that extinction threats are clustered on the phylogeny; however this is not always a sufficient condition to cause higher loss of phylogenetic diversity in comparison to a scenario of random extinctions. Extinctions of the most evolutionarily distinct species and the shape of phylogenetic trees are additional factors that can elevate losses of evolutionary history. Consequently, impacts of species extinctions differ among groups and regions, and even if global losses are low within large groups, losses can be high among subgroups or within some regions. Further, we show that PD and ED are poorly protected by current conservation practices. While evolutionary history can be indirectly protected by current conservation schemes, optimizing its preservation requires integrating phylogenetic indices with those that capture rarity and extinction risk. Measures based on PD and ED could bring solutions to conservation issues, however they are still rarely used in practice, probably because the reasons to protect evolutionary history are not clear for practitioners or due to a lack of data. However, important advances have been made in the availability of phylogenetic trees and methods for their construction, as well as assessments of extinction risk. Some challenges remain, and looking forward, research should prioritize the assessment of expected PD and ED loss for more taxonomic

How evolutionary principles improve the understanding of human health and disease.

Science.gov (United States)

Gluckman, Peter D; Low, Felicia M; Buklijas, Tatjana; Hanson, Mark A; Beedle, Alan S

2011-03-01

An appreciation of the fundamental principles of evolutionary biology provides new insights into major diseases and enables an integrated understanding of human biology and medicine. However, there is a lack of awareness of their importance amongst physicians, medical researchers, and educators, all of whom tend to focus on the mechanistic (proximate) basis for disease, excluding consideration of evolutionary (ultimate) reasons. The key principles of evolutionary medicine are that selection acts on fitness, not health or longevity; that our evolutionary history does not cause disease, but rather impacts on our risk of disease in particular environments; and that we are now living in novel environments compared to those in which we evolved. We consider these evolutionary principles in conjunction with population genetics and describe several pathways by which evolutionary processes can affect disease risk. These perspectives provide a more cohesive framework for gaining insights into the determinants of health and disease. Coupled with complementary insights offered by advances in genomic, epigenetic, and developmental biology research, evolutionary perspectives offer an important addition to understanding disease. Further, there are a number of aspects of evolutionary medicine that can add considerably to studies in other domains of contemporary evolutionary studies.

Theoretical Approaches in Evolutionary Ecology: Environmental Feedback as a Unifying Perspective.

Science.gov (United States)

Lion, Sébastien

2018-01-01

Evolutionary biology and ecology have a strong theoretical underpinning, and this has fostered a variety of modeling approaches. A major challenge of this theoretical work has been to unravel the tangled feedback loop between ecology and evolution. This has prompted the development of two main classes of models. While quantitative genetics models jointly consider the ecological and evolutionary dynamics of a focal population, a separation of timescales between ecology and evolution is assumed by evolutionary game theory, adaptive dynamics, and inclusive fitness theory. As a result, theoretical evolutionary ecology tends to be divided among different schools of thought, with different toolboxes and motivations. My aim in this synthesis is to highlight the connections between these different approaches and clarify the current state of theory in evolutionary ecology. Central to this approach is to make explicit the dependence on environmental dynamics of the population and evolutionary dynamics, thereby materializing the eco-evolutionary feedback loop. This perspective sheds light on the interplay between environmental feedback and the timescales of ecological and evolutionary processes. I conclude by discussing some potential extensions and challenges to our current theoretical understanding of eco-evolutionary dynamics.

What Is Sexual Orientation All About? Explaining an Evolutionary Paradox

OpenAIRE

Brad Bowins

2015-01-01

Numerous psychological, biological, and evolutionary theories have been proposed to explain sexual orientation. For a theory to be valid it must account for the evolutionary or Darwinian paradox of how homosexual behavior seemingly blocking evolutionary fitness could have evolved. Typically it is only evolutionary based theories that attempt to address this issue. All theories proposed to date have limitations, a major one being that they tend to be specific for male or female sexual orientat...

The Relationship between Music Preferences of Different Mode and Tempo and Personality Traits--Implications for Music Pedagogy

Science.gov (United States)

Dobrota, Snježana; Reic Ercegovac, Ina

2015-01-01

The aim of this research was to examine the relationship between music preferences of different mode and tempo and personality traits. The survey included 323 students who had to fill out the following tests: questionnaire of music preferences, scale of optimism and pessimism and International Personality Item Pool for measuring Big Five…

Studying the evolutionary significance of thermal adaptation in ectotherms: The diversification of amphibians' energetics.

Science.gov (United States)

Nespolo, Roberto F; Figueroa, Julio; Solano-Iguaran, Jaiber J

2017-08-01

A fundamental problem in evolutionary biology is the understanding of the factors that promote or constrain adaptive evolution, and assessing the role of natural selection in this process. Here, comparative phylogenetics, that is, using phylogenetic information and traits to infer evolutionary processes has been a major paradigm . In this study, we discuss Ornstein-Uhlenbeck models (OU) in the context of thermal adaptation in ectotherms. We specifically applied this approach to study amphibians's evolution and energy metabolism. It has been hypothesized that amphibians exploit adaptive zones characterized by low energy expenditure, which generate specific predictions in terms of the patterns of diversification in standard metabolic rate (SMR). We complied whole-animal metabolic rates for 122 species of amphibians, and adjusted several models of diversification. According to the adaptive zone hypothesis, we expected: (1) to find "accelerated evolution" in SMR (i.e., diversification above Brownian Motion expectations, BM), (2) that a model assuming evolutionary optima (i.e., an OU model) fits better than a white-noise model and (3) that a model assuming multiple optima (according to the three amphibians's orders) fits better than a model assuming a single optimum. As predicted, we found that the diversification of SMR occurred most of the time, above BM expectations. Also, we found that a model assuming an optimum explained the data in a better way than a white-noise model. However, we did not find evidence that an OU model with multiple optima fits the data better, suggesting a single optimum in SMR for Anura, Caudata and Gymnophiona. These results show how comparative phylogenetics could be applied for testing adaptive hypotheses regarding history and physiological performance in ectotherms. Copyright © 2016 Elsevier Ltd. All rights reserved.

The evolutionary implications of epigenetic inheritance.

Science.gov (United States)

Jablonka, Eva

2017-10-06

The Modern Evolutionary Synthesis (MS) forged in the mid-twentieth century was built on a notion of heredity that excluded soft inheritance, the inheritance of the effects of developmental modifications. However, the discovery of molecular mechanisms that generate random and developmentally induced epigenetic variations is leading to a broadening of the notion of biological heredity that has consequences for ideas about evolution. After presenting some old challenges to the MS that were raised, among others, by Karl Popper, I discuss recent research on epigenetic inheritance, which provides experimental and theoretical support for these challenges. There is now good evidence that epigenetic inheritance is ubiquitous and is involved in adaptive evolution and macroevolution. I argue that the many evolutionary consequences of epigenetic inheritance open up new research areas and require the extension of the evolutionary synthesis beyond the current neo-Darwinian model.

Evolutionary Computing for Intelligent Power System Optimization and Control

DEFF Research Database (Denmark)

This new book focuses on how evolutionary computing techniques benefit engineering research and development tasks by converting practical problems of growing complexities into simple formulations, thus largely reducing development efforts. This book begins with an overview of the optimization the...... theory and modern evolutionary computing techniques, and goes on to cover specific applications of evolutionary computing to power system optimization and control problems....

Investigation of Method for Changing Impression of Musical Piece by Changing its Tempo

Science.gov (United States)

Fukumoto, Makoto; Okamatsu, Keita; Matsuo, Kazuhisa

We propose a simple method that changes impression of musical piece by changing its tempo and investigate psycho-physiological effects of the method with listening experiment. In the experiment, 8 subjects listened same musical pieces with various tempi, and analysis of heartbeat and Semantic-Differential method were used. In 6 out of 10 adjective pairs, inverted-U shapes were observed, and peak tempi of them were different. Moreover, “relaxed” evaluation might be related to listener's heart rate in rest. These results suggest possibility of constructing novel media player that changes impression of musical piece.

Perceived social isolation, evolutionary fitness and health outcomes: a lifespan approach.

Science.gov (United States)

Hawkley, Louise C; Capitanio, John P

2015-05-26

Sociality permeates each of the fundamental motives of human existence and plays a critical role in evolutionary fitness across the lifespan. Evidence for this thesis draws from research linking deficits in social relationship--as indexed by perceived social isolation (i.e. loneliness)--with adverse health and fitness consequences at each developmental stage of life. Outcomes include depression, poor sleep quality, impaired executive function, accelerated cognitive decline, unfavourable cardiovascular function, impaired immunity, altered hypothalamic pituitary-adrenocortical activity, a pro-inflammatory gene expression profile and earlier mortality. Gaps in this research are summarized with suggestions for future research. In addition, we argue that a better understanding of naturally occurring variation in loneliness, and its physiological and psychological underpinnings, in non-human species may be a valuable direction to better understand the persistence of a 'lonely' phenotype in social species, and its consequences for health and fitness. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

Diego Velázquez e os retratos de Felipe IV: A pintura Barroca e a idéia de tempo na sociedade espanhola do século XVII

Directory of Open Access Journals (Sweden)

Susana Aparecida da Silva

2012-08-01

Full Text Available Esta pesquisa reflete a respeito da possibilidade de se analisar a idéia de tempo na Espanha Barroca do século XVII através de cinco retratos feitos pelo pintor espanhol Diego Velázquez (1599-1660. Estes retratos são feitos após o período em que o pintor é admitido na corte de Felipe IV da Espanha (1605-1665 como pintor oficial. As fontes visuais selecionadas para esta pesquisa no sentido de possibilitar a análise da idéia de tempo são retratos do rei feitos por Diego Velázquez e representam o rei jovem e posteriormente envelhecido. Acredita-se que a idéia de tempo para Velázquez tenha estreita relação com a sociedade barroca espanhola do século XVII na qual ele está inserido. Neste sentido, as representações do poder e do envelhecimento do monarca possíveis de serem vistas nas pinturas de Velázquez contribuem para se pensar a concepção de tempo do artista e da sociedade espanhola daquele período

Plasma accelerators

International Nuclear Information System (INIS)

Bingham, R.; Angelis, U. de; Johnston, T.W.

1991-01-01

Recently attention has focused on charged particle acceleration in a plasma by a fast, large amplitude, longitudinal electron plasma wave. The plasma beat wave and plasma wakefield accelerators are two efficient ways of producing ultra-high accelerating gradients. Starting with the plasma beat wave accelerator (PBWA) and laser wakefield accelerator (LWFA) schemes and the plasma wakefield accelerator (PWFA) steady progress has been made in theory, simulations and experiments. Computations are presented for the study of LWFA. (author)

The great opportunity: Evolutionary applications to medicine and public health.

Science.gov (United States)

Nesse, Randolph M; Stearns, Stephen C

2008-02-01

Evolutionary biology is an essential basic science for medicine, but few doctors and medical researchers are familiar with its most relevant principles. Most medical schools have geneticists who understand evolution, but few have even one evolutionary biologist to suggest other possible applications. The canyon between evolutionary biology and medicine is wide. The question is whether they offer each other enough to make bridge building worthwhile. What benefits could be expected if evolution were brought fully to bear on the problems of medicine? How would studying medical problems advance evolutionary research? Do doctors need to learn evolution, or is it valuable mainly for researchers? What practical steps will promote the application of evolutionary biology in the areas of medicine where it offers the most? To address these questions, we review current and potential applications of evolutionary biology to medicine and public health. Some evolutionary technologies, such as population genetics, serial transfer production of live vaccines, and phylogenetic analysis, have been widely applied. Other areas, such as infectious disease and aging research, illustrate the dramatic recent progress made possible by evolutionary insights. In still other areas, such as epidemiology, psychiatry, and understanding the regulation of bodily defenses, applying evolutionary principles remains an open opportunity. In addition to the utility of specific applications, an evolutionary perspective fundamentally challenges the prevalent but fundamentally incorrect metaphor of the body as a machine designed by an engineer. Bodies are vulnerable to disease - and remarkably resilient - precisely because they are not machines built from a plan. They are, instead, bundles of compromises shaped by natural selection in small increments to maximize reproduction, not health. Understanding the body as a product of natural selection, not design, offers new research questions and a framework for

Co-loading and intestine-specific delivery of multiple antioxidants in pH-responsive microspheres based on TEMPO-oxidized polysaccharides