Annual General Meeting of the Pension Fund

CERN Multimedia

2006-01-01

Annual General Meeting to be held in the CERN Main Auditorium on Wednesday 1st November 2006 at 2.00 p.m. The Agenda will be as follows: Opening Remarks - F. Ferrini Results and presentation of the 2005 Annual Report- Future challenges associated with asset-liability modelling and asset allocation Copies of the 2005 Annual Report are available from departmental secretariats. - C. Cuénoud Recent development of the actuarial position of the Pension Fund - J.-P. Matheys Questions from members and beneficiaries Persons wishing to ask questions are encouraged to submit them in writing in advance, where possible, and addressed to the Fund Administrator Mr C. Cuénoud. Conclusions - F. Ferrini As usual, participants are invited to drinks after the meeting. NB The minutes of the 2005 AGM are available from the Administration of the Fund: Tel: (+4122) 767 27 42 e-mail: Sophia.Revol@cern.ch)

Annual General Meeting of the Pension Fund

CERN Multimedia

2006-01-01

Annual General Meeting to be held in the CERN Main Auditorium on Wednesday 1st November 2006 at 2.00 p.m. The Agenda will be as follows: Opening Remarks - F. Ferrini Results and presentation of the 2005 Annual Report- Future challenges associated with asset-liability modelling and asset allocation Copies of the 2005 Annual Report are available from departmental secretariats. - C. Cuénoud Recent development of the actuarial position of the Pension Fund - J.-P. Matheys Questions from members and beneficiaries Persons wishing to ask questions are encouraged to submit them in writing in advance, where possible, addressed to the Fund's Administrator, Mr C. Cuénoud. Conclusions - F. Ferrini As usual, participants are invited to drinks after the meeting. NB The minutes of the 2005 AGM are available from the Administration of the Fund: Tel: (+4122) 767 27 42 e-mail: Sophia.Revol@cern.ch)

ASIST 2002 annual meeting

CERN Multimedia

Peek, R

2003-01-01

Review of discussions and presentations at the American Society for Information Science and Technology 2002 annual meeting. Topics covered included new models of scholarly publishing and the development of the semantic web (1 page).

Annual general meeting of the pension fund

CERN Multimedia

2006-01-01

All members and beneficiaries of the Pension Fund are invited to attend the Annual General Meeting to be held in the CERN Main Auditorium on Wednesday 1st November 2006 at 2.00 p.m. The Agenda will be as follows: Opening Remarks - F. Ferrini Results and presentation of the 2005 Annual Report- Future challenges associated with asset-liability modelling and asset allocation - C. Cuénoud Copies of the 2005 Annual Report are available from Departmental secretariats. Recent development of the actuarial position of the Pension Fund - J.-P. Matheys Questions from members and beneficiaries Persons wishing to ask questions are encouraged to submit them in writing in advance, where possible, to the Fund's Administrator, Mr C. Cuénoud. Conclusions - F. Ferrini As usual, participants are invited to ayttend a drink after the meeting. NB: The minutes of the 2005 AGM are available from the Administration of the Fund: Tel: +41 22 767 27 42, e-mail: Sophia.Revol@cern.ch).

Annual General Meeting of the Pension Fund

CERN Multimedia

2006-01-01

All members and beneficiaries of the Pension Fund are invited to attend the Annual General Meeting to be held in the CERN Main Auditoriumon Wednesday 1st November 2006 at 2.00 p.m. The Agenda will be as follows: Opening Remarks - F. Ferrini Results and presentation of the 2005 Annual Report- Future challenges associated with asset-liability modelling and asset allocation Copies of the 2005 Annual Report are available from departmental secretariats. - C. Cuénoud Recent development of the actuarial position of the Pension Fund - J.-P. Matheys Questions from members and beneficiaries Persons wishing to ask questions are encouraged to submit them in writing in advance, where possible, and addressed to the Fund Administrator Mr C. Cuénoud. Conclusions - F. Ferrini As usual, participants are invited to drinks after the meeting. NB: The minutes of the 2005 AGM are available from the Administration of the Fund: Tel: (+4122) 767 27 42 e-mail: Sophia.Revol@cern.ch)

ABC Technology Development Program

International Nuclear Information System (INIS)

1994-01-01

The Accelerator-Based Conversion (ABC) facility will be designed to accomplish the following mission: 'Provide a weapon's grade plutonium disposition capability in a safe, economical, and environmentally sound manner on a prudent schedule for [50] tons of weapon's grade plutonium to be disposed on in [20] years.' This mission is supported by four major objectives: provide a reliable plutonium disposition capability within the next [15] years; provide a level of safety and of safety assurance that meets or exceeds that afforded to the public by modern commercial nuclear power plants; meet or exceed all applicable federal, state, and local regulations or standards for environmental compliance; manage the program in a cost effective manner. The ABC Technology Development Program defines the technology development activities that are required to accomplish this mission. The technology development tasks are related to the following topics: blanket system; vessel systems; reactivity control systems; heat transport system components; energy conversion systems; shutdown heat transport systems components; auxiliary systems; technology demonstrations - large scale experiments

International Working Group on Fast Reactors Second Annual Meeting. Summary Report

International Nuclear Information System (INIS)

1969-01-01

The Agenda of the Meeting was as follows: Opening of the meeting. 2. Appraisal of the IWGFB's activity for the period from the first annual meeting of the Group. 3. Comments on national programmes on fast breeder reactors. 4. Presentation of general findings and conclusions of national and regional meetings on fast reactor problems held in represented countries and international organisations last year. 5. Comments on the programmes of international meetings on fast reactors to be held in 1969. 6. Consideration of a schedule for meetings on fast reactors in 1970. 7. Suggestions for the topics and location of specialists' meetings in 1969-1970. 8. Suggestions for reviews and studies in the field of fast reactors. 9. The time and place of the third annual meeting of the IWGFR. 10. Closing of the meeting

Selections from the ABC 2013 Annual Convention, New Orleans, Louisiana: A Gumbo of Favorite Assignments: Global, Communicating Complex Information, Short-Message Packaging

Science.gov (United States)

Whalen, D. Joel

2014-01-01

This article, the first of a two-part series, catalogs teaching innovations presented at the 2013 Association for Business Communication (ABC) Annual Convention, New Orleans. They were presented during the My Favorite Assignment session. The 11 Favorite Assignments featured here offer the reader a variety of learning experiences including…

Annual Information Meeting of the Pension Fund

CERN Multimedia

2014-01-01

All members and beneficiaries of the Pension Fund are invited to attend the Annual Information Meeting.   Annual Information Meeting to be held in the CERN Council Chamber on Tuesday, 16 September 2014 from 9.00 a.m. to 10.30 a.m. Copies of the 2013 Pension Fund Financial Statements are already available in accessible PDF on the Pension Fund website and will also be distributed at this session. Coffee and croissants will be served prior to the meeting as of 8:30 a.m. N.B. Date change: 16 September 2014

Annual General Meetings

OpenAIRE

2009-01-01

We have produced this information booklet to explain why companies must – by law – hold an Annual General Meeting (AGM). The laws which cover AGMs are known as the Companies Acts. This guide gives only a summary of the rules for AGMs. If you have a concern about the AGM of a particular company, you should get independent legal advice.

Annual Information Meeting of the Pension Fund | 26 October

CERN Multimedia

2016-01-01

All members and beneficiaries of the Pension Fund are invited to attend the Annual Information Meeting of the Pension Fund.   Meeting to be held in the Main Auditorium on Wednesday 26 October 2016 from 9:30 a.m. to 11:30 a.m. Following a presentation by the Chief Executive Officer of the Fund there will be a Questions and Answers session. Members and Beneficiaries are welcome to send questions in advance of the meeting by post to: Mr Matthew Eyton-Jones “Annual Information Meeting” CEO CERN Pension Fund Office 5-5-012, Postbox C23800 CH- 1211 Geneva 23 - Switzerland Copies of the 2015 Pension Fund Annual Report & Financial Statements are already available in accessible PDF on the Pension Fund website and will also be distributed at the annual meeting. *Coffee and croissants will be served prior to the meeting as of 9:00 a.m.*

CO₂ capture from IGCC gas streams using the AC-ABC process

Energy Technology Data Exchange (ETDEWEB)

Nagar, Anoop [SRI International, Menlo Park, CA (United States); McLaughlin, Elisabeth [SRI International, Menlo Park, CA (United States); Hornbostel, Marc [SRI International, Menlo Park, CA (United States); Krishnan, Gopala [SRI International, Menlo Park, CA (United States); Jayaweera, Indira [SRI International, Menlo Park, CA (United States)

2017-02-16

The objective of this project was to develop a novel, low-cost CO₂ capture process from pre-combustion gas streams. The bench-scale work was conducted at the SRI International. A 0.15-MWe integrated pilot plant was constructed and operated for over 700 hours at the National Carbon Capture Center, Wilsonville, AL. The AC-ABC (ammonium carbonate-ammonium bicarbonate) process for capture of CO₂ and H₂S from the pre-combustion gas stream offers many advantages over Selexol-based technology. The process relies on the simple chemistry of the NH₃-CO₂-H₂O-H₂S system and on the ability of the aqueous ammoniated solution to absorb CO₂ at near ambient temperatures and to release it as a high-purity, high-pressure gas at a moderately elevated regeneration temperature. It is estimated the increase in cost of electricity (COE) with the AC-ABC process will be ~ 30%, and the cost of CO₂ captured is projected to be less than $27/metric ton of CO₂ while meeting 90% CO₂ capture goal. The Bechtel Pressure Swing Claus (BPSC) is a complementary technology offered by Bechtel Hydrocarbon Technology Solutions, Inc. BPSC is a high-pressure, sub-dew-point Claus process that allows for nearly complete removal of H₂S from a gas stream. It operates at gasifier pressures and moderate temperatures and does not affect CO₂ content. When coupled with AC-ABC, the combined technologies allow a nearly pure CO₂ stream to be captured at high pressure, something which Selexol and other solvent-based technologies cannot achieve.

Volume-Dependent Overestimation of Spontaneous Intracerebral Hematoma Volume by the ABC/2 Formula

International Nuclear Information System (INIS)

Chih-Wei Wang; Chun-Jung Juan; Hsian-He Hsu; Hua-Shan Liu; Cheng-Yu Chen; Chun-Jen Hsueh; Hung-Wen Kao; Guo-Shu Huang; Yi-Jui Liu; Chung-Ping Lo

2009-01-01

Background: Although the ABC/2 formula has been widely used to estimate the volume of intracerebral hematoma (ICH), the formula tends to overestimate hematoma volume. The volume-related imprecision of the ABC/2 formula has not been documented quantitatively. Purpose: To investigate the volume-dependent overestimation of the ABC/2 formula by comparing it with computer-assisted volumetric analysis (CAVA). Material and Methods: Forty patients who had suffered spontaneous ICH and who had undergone non-enhanced brain computed tomography scans were enrolled in this study. The ICH volume was estimated based on the ABC/2 formula and also calculated by CAVA. Based on the ICH volume calculated by the CAVA method, the patients were divided into three groups: group 1 consisted of 17 patients with an ICH volume of less than 20 ml; group 2 comprised 13 patients with an ICH volume of 20 to 40 ml; and group 3 was composed of 10 patients with an ICH volume larger than 40 ml. Results: The mean estimated hematoma volume was 43.6 ml when using the ABC/2 formula, compared with 33.8 ml when using the CAVA method. The mean estimated difference was 1.3 ml, 4.4 ml, and 31.4 ml for groups 1, 2, and 3, respectively, corresponding to an estimation error of 9.9%, 16.7%, and 37.1% by the ABC/2 formula (P<0.05). Conclusion: The ABC/2 formula significantly overestimates the volume of ICH. A positive association between the estimation error and the volume of ICH is demonstrated

78th Annual Meeting of the Psychometric Society

CERN Document Server

Bolt, Daniel; Ark, L; Wang, Wen-Chung

2015-01-01

The 78th Annual Meeting of the Psychometric Society (IMPS) builds on the Psychometric Society's mission to share quantitative methods relevant to psychology. The chapters of this volume present cutting-edge work in the field. Topics include studies of item response theory, computerized adaptive testing, cognitive diagnostic modeling, and psychological scaling. Additional psychometric topics relate to structural equation modeling, factor analysis, causal modeling, mediation, missing data methods, and longitudinal data analysis, among others. The papers in this volume will be especially useful for researchers in the social sciences who use quantitative methods. Prior knowledge of statistical methods is recommended. The 78th annual meeting took place in Arnhem, The Netherlands between July 22nd and 26th, 2013. The previous volume to showcase work from the Psychometric Society’s Meeting is New Developments in Quantitative Psychology: Presentations from the 77th Annual Psychometric Society Meeting (Springer, 201...

2nd Annual DOE-ERSP PI Meeting: Abstracts

Energy Technology Data Exchange (ETDEWEB)

Hazen, Terry C.

2007-03-14

Welcome to the annual 2007 Environmental Remediation Sciences Program (ERSP) Principal Investigators (PIs) meeting. The purpose of this meeting is to bring together all of the lead PIs and key Co-PIs in the program to share and review the results of funded research from the past year. This meeting allows program managers from the Environmental Remediation Sciences Division (ERSD) within the Office of Biological and Environmental Research (OBER) to gauge the progress and significance of the funded research, and it is also an important venue to showcase ERSP research to interested parties within DOE and other invited federal agency representatives. Additionally, these meetings should serve as an opportunity for funded PIs to view their research in the context of the entire ERSP portfolio. Past ERSP meetings have been very important venues for detailed discussion of research results among PIs, development of new research ideas, fostering new collaborations and discussion with ERSD program managers on future research efforts and/or initiatives within the program. In short, these meetings are an important resource for both program managers and PIs. There will be only one ERSP PI meeting for 2007. In years past, ERSD has sponsored two PI meetings, one in the spring and a separate meeting in the fall that focused primarily on field research. However, this format tends to insulate laboratory-based research from the field research sponsored in the program and is incompatible with the ERSD view that laboratory-based research should progress towards understanding the relevant processes in natural environments at the field scale. Therefore the agenda for this year's PI meeting is well integrated with both lab-based and field-based projects, to allow for detailed discussion between PIs involved in each area. In the agenda, you will notice a more relaxed format than in years past. This year's meeting spans four days, but is less heavily regimented in terms of oral

Dashboard auditing of ABC (Activity-Based Costing). Theoretical approaches

OpenAIRE

Căpuşneanu, Sorinel/I

2009-01-01

This article aims to define the dashboard auditing according to the specifics of Activity-Based Costing method (ABC). It describes the main objectives of dashboard auditing, the criteria that a dashboard auditor should meet and the step-by-step stages of the entire dashboard auditing process of an enterprise from steel industry according to the Activity-Based Costing method (ABC).

Calculating the tumor volume of acoustic neuromas: comparison of ABC/2 formula with planimetry method.

Science.gov (United States)

Yu, Yi-Lin; Lee, Meei-Shyuan; Juan, Chun-Jung; Hueng, Dueng-Yuan

2013-08-01

The ABC/2 equation is commonly applied to measure the volume of intracranial hematoma. However, the precision of ABC/2 equation in estimating the tumor volume of acoustic neuromas is less addressed. The study is to evaluate the accuracy of the ABC/2 formula by comparing with planimetry method for estimating the tumor volumes. Thirty-two patients diagnosed with acoustic neuroma received contrast-enhanced magnetic resonance imaging of brain were recruited. The volume was calculated by the ABC/2 equation and planimetry method (defined as exact volume) at the same time. The 32 patients were divided into three groups by tumor volume to avoid volume-dependent overestimation (6 ml). The tumor volume by ABC/2 method was highly correlated to that calculated by planimetry method using linear regression analysis (R2=0.985). Pearson correlation coefficient (r=0.993, pABC/2 formula is an easy method in estimating the tumor volume of acoustic neuromas that is not inferior to planimetry method. Copyright © 2013 Elsevier B.V. All rights reserved.

Annual Meetings | Events | Indian Academy of Sciences

Indian Academy of Sciences (India)

two days in early July) is held in Bangalore, while the location of the Annual meeting of the Academy (three days around the 7th of November) changes each year. During these meetings, there are symposia on special topics as well as ...

Fifteenth annual meeting of the International Working Group on Fast Reactors. Summary report

International Nuclear Information System (INIS)

1982-09-01

The Fifteenth Annual Meeting of the IWGFR was held in accordance with the recommendation of the previous Annual Group Meeting, in Obninsk, USSR, Vienna from 30 March to 2 April 1982. The meeting was attended by the Member States of the group: France, the Federal Republic of Germany, Italy, Japan, the United Kingdom, and the USA, as well as by representatives from CEC, IAEA and OECD and observer from the USSR. This document includes: review of the IWGFR Activities for the period since the Eleventh Annual Meeting of the Group; preliminary programme of international conference on breeder reactors as a world energy resource and the breeder fuel cycle; list of meetings on atomic energy which may be of interest to the IWGFR Members; IWGFR criteria for supporting some of the international conferences; list of proposed topics for the IWGFR Specialists' Meetings; list of topics for review articles on LMFBR recommended for publication by the IAEA; list of meetings sponsored by the IWGFR; a list of members of the International Working Group on Fast Reactors

Fifteenth annual meeting of the International Working Group on Fast Reactors. Summary report

Energy Technology Data Exchange (ETDEWEB)

NONE

1982-09-01

The Fifteenth Annual Meeting of the IWGFR was held in accordance with the recommendation of the previous Annual Group Meeting, in Obninsk, USSR, Vienna from 30 March to 2 April 1982. The meeting was attended by the Member States of the group: France, the Federal Republic of Germany, Italy, Japan, the United Kingdom, and the USA, as well as by representatives from CEC, IAEA and OECD and observer from the USSR. This document includes: review of the IWGFR Activities for the period since the Eleventh Annual Meeting of the Group; preliminary programme of international conference on breeder reactors as a world energy resource and the breeder fuel cycle; list of meetings on atomic energy which may be of interest to the IWGFR Members; IWGFR criteria for supporting some of the international conferences; list of proposed topics for the IWGFR Specialists' Meetings; list of topics for review articles on LMFBR recommended for publication by the IAEA; list of meetings sponsored by the IWGFR; a list of members of the International Working Group on Fast Reactors.

15 September: Annual Information Meeting of the Pension Fund

CERN Multimedia

2015-01-01

All members and beneficiaries of the Pension Fund are invited to attend the Annual Information Meeting. *** Please note the room change *** CERN Main Auditorium Tuesday, 15 September 2015 9:30 a.m. - 11:30 a.m. Following a presentation by the Chief Executive Officer of the Fund there will be a Questions and Answers session. Members and Beneficiaries are welcome to send questions in advance of the meeting by post to: Mr Matthew Eyton-Jones “Annual Information Meeting” CEO - CERN Pension Fund Office 5-5-012, Postbox C23800 CH- 1211 Geneva 23 - Switzerland Copies of the 2014 Pension Fund Financial Statements are already available as a printable PDF on the Pension Fund website (http://pensionfund.cern.ch/en/financial-management/financial-statements) and will also be distributed at the annual meeting. *Coffee and croissants will be served prior to the meeting as of 9:00 a.m.* CERN Pension Fund

[Designing the Annual Meeting and Active Learning System].

Science.gov (United States)

Kawamura, Kazumi

2018-01-01

　At the 10th Annual Meeting of the Japanese Society for Pharmaceutical Palliative Care and Sciences our theme centered on active learning systems where adult learners engage on their own initiative. Many of the participants were pharmacists active in clinical practices. Regardless of their specialized skill-sets, pharmacists are constantly faced with difficult challenges in their daily work. Passive, one-way lectures are one resource for them, but unfortunately such lectures provide limited insights for resolving concrete problems. The present meeting aimed to show participants how to obtain information they need to solve specific real-world problems. This paper summarizes how we planned this year's meeting, including details about the debate symposium, social lunch, and online questionnaires. All these elements had the end goal of enabling learners proactivity to become their own best resource for learning. It is sincerely hoped that the design and execution of this meeting will prove resourceful for future annual meetings.

35th Annual meeting proceedings. Volume XXIII

International Nuclear Information System (INIS)

Anon.

1994-01-01

This report contains the proceedings of the 35th Annual Meeting of the Institute of Nuclear Materials Management. INMM is a nonprofit organization incorporated in the state of Ohio. This meeting was held at The Registry Resort Hotel in Naples, Florida, USA, July 17-20, 1994. Separate abstracts were entered into the Energy Data Base

A 6-Nucleotide Regulatory Motif within the AbcR Small RNAs of Brucella abortus Mediates Host-Pathogen Interactions.

Science.gov (United States)

Sheehan, Lauren M; Caswell, Clayton C

2017-06-06

In Brucella abortus , two small RNAs (sRNAs), AbcR1 and AbcR2, are responsible for regulating transcripts encoding ABC-type transport systems. AbcR1 and AbcR2 are required for Brucella virulence, as a double chromosomal deletion of both sRNAs results in attenuation in mice. Although these sRNAs are responsible for targeting transcripts for degradation, the mechanism utilized by the AbcR sRNAs to regulate mRNA in Brucella has not been described. Here, two motifs (M1 and M2) were identified in AbcR1 and AbcR2, and complementary motif sequences were defined in AbcR-regulated transcripts. Site-directed mutagenesis of M1 or M2 or of both M1 and M2 in the sRNAs revealed transcripts to be targeted by one or both motifs. Electrophoretic mobility shift assays revealed direct, concentration-dependent binding of both AbcR sRNAs to a target mRNA sequence. These experiments genetically and biochemically characterized two indispensable motifs within the AbcR sRNAs that bind to and regulate transcripts. Additionally, cellular and animal models of infection demonstrated that only M2 in the AbcR sRNAs is required for Brucella virulence. Furthermore, one of the M2-regulated targets, BAB2_0612, was found to be critical for the virulence of B. abortus in a mouse model of infection. Although these sRNAs are highly conserved among Alphaproteobacteria , the present report displays how gene regulation mediated by the AbcR sRNAs has diverged to meet the intricate regulatory requirements of each particular organism and its unique biological niche. IMPORTANCE Small RNAs (sRNAs) are important components of bacterial regulation, allowing organisms to quickly adapt to changes in their environments. The AbcR sRNAs are highly conserved throughout the Alphaproteobacteria and negatively regulate myriad transcripts, many encoding ABC-type transport systems. In Brucella abortus , AbcR1 and AbcR2 are functionally redundant, as only a double abcR1 abcR2 ( abcR1 / 2 ) deletion results in attenuation in

Meals at medical specialty society annual meetings: a preliminary assessment.

Science.gov (United States)

La Puma, John; Schiedermayer, David; Becker, Jennifer

2003-01-01

Little isd known about how meals are chosen for medical meetings. We surveyed the annual meeting planners for 20 major specialty societies. Thirteen (65%) responded; all were currently planning their next meeting. Attendance in 2000 was reported at 113,477 physicians, with 2 million planned meals and snacks. No physician was named as responsible for food choices; the meeting planner and staff were primarily responsible for deciding what food to serve, excluding exhibit halls. Twelve (92%) respondents rated "available budget" as the most important factor. "Nutritional guidelines" were rated "very important" by eight of 13 (63%). However, no specific nutritional guidelines could be identified by any planner. All respondents indicated that members would attend a meeting if "healthy" food were the only option. For 2000, 100% of respondents indicated that for each lunch and for each dinner, a dessert had been included. No annual meeting and no planned 2001 meeting excluded potato chips, snack mixes, or candies at breaks; soda pop was offered at each break. Most respondents (89%) relied on a concluding questionnaire about the meeting facilities to evaluate the food. Respondents reported no difference in charges for "special meals," including vegetarian and kosher meals. Physicians may be unaware that some food served at medical meetings may impair learning, with excessive calorie, fat, and carbohydrate consumption. Small changes can improve the quality of food and beverages selected, without increased cost, and provide choices that conform to national nutritional guidelines. Medical meetings should serve flavorful, healthful food.

Hamiltonian ABC

NARCIS (Netherlands)

Meeds, E.; Leenders, R.; Welling, M.; Meila, M.; Heskes, T.

2015-01-01

Approximate Bayesian computation (ABC) is a powerful and elegant framework for performing inference in simulation-based models. However, due to the difficulty in scaling likelihood estimates, ABC remains useful for relatively lowdimensional problems. We introduce Hamiltonian ABC (HABC), a set of

4th Annual DOE-ERSP PI Meeting: Abstracts

International Nuclear Information System (INIS)

Hazen, Terry C.

2009-01-01

This contains abstracts from the 2009 Annual Environmental Remediation Sciences Program (ERSP) Principal Investigators (PI) Meeting. The ERSP seeks to advance fundamental science to understand, predict, and mitigate the impacts of environmental contamination from past nuclear weapons production and provide a scientific basis for the long-term stewardship of nuclear waste disposal. These ambitious goals cannot be achieved by any one project alone. Therefore, ERSP funds a combination of research programs at the DOE national laboratories, individual projects at universities and federal agencies, and large long(er)-term field site research. Integration of these activities to advance the ERSP goals is a constant challenge, but made significantly simpler by bringing together all funded ERSP researchers once a year to discuss the very latest research results. It is at these meetings where new ideas and/or scientific advancements in support of ERSP goals can be discussed and openly debated among all PIs in the program. The ERSP thrives, in part, on the new ideas, concepts, scientific connections, and collaborations generated as a result of these meetings. The annual PI Meeting is very much a working meeting with three major goals: (1) to provide opportunities for scientific interaction among the ERSP scientists, a critical element for the program; (2) to provide the ERSP program staff with an opportunity to evaluate the progress of each program and project; and (3) to showcase the ERSP to interested parties within DOE and within other federal agencies In addition to program managers from within OBER, there will be representatives from other offices within DOE and other federal agencies in attandance at the meeting.

4th Annual DOE-ERSP PI Meeting: Abstracts

Energy Technology Data Exchange (ETDEWEB)

Hazen, Terry C.

2009-03-01

This contains abstracts from the 2009 Annual Environmental Remediation Sciences Program (ERSP) Principal Investigators (PI) Meeting. The ERSP seeks to advance fundamental science to understand, predict, and mitigate the impacts of environmental contamination from past nuclear weapons production and provide a scientific basis for the long-term stewardship of nuclear waste disposal. These ambitious goals cannot be achieved by any one project alone. Therefore, ERSP funds a combination of research programs at the DOE national laboratories, individual projects at universities and federal agencies, and large long(er)-term field site research. Integration of these activities to advance the ERSP goals is a constant challenge, but made significantly simpler by bringing together all funded ERSP researchers once a year to discuss the very latest research results. It is at these meetings where new ideas and/or scientific advancements in support of ERSP goals can be discussed and openly debated among all PIs in the program. The ERSP thrives, in part, on the new ideas, concepts, scientific connections, and collaborations generated as a result of these meetings. The annual PI Meeting is very much a working meeting with three major goals: (1) to provide opportunities for scientific interaction among the ERSP scientists, a critical element for the program; (2) to provide the ERSP program staff with an opportunity to evaluate the progress of each program and project; and (3) to showcase the ERSP to interested parties within DOE and within other federal agencies In addition to program managers from within OBER, there will be representatives from other offices within DOE and other federal agencies in attandance at the meeting.

Annual Information Meeting of the Pension Fund

CERN Multimedia

2013-01-01

All members and beneficiaries of the Pension Fund are invited to attend the   Annual Information Meeting to be held in the CERN Council Chamber on  Wednesday, 11 September 2013 from 10.00 a.m. to 12.00 midday. Copies of the 2012 Pension Fund Financial Statements can be obtained from departmental secretariats and will also be available at the meeting.

Comparing the accuracy of ABC and time-driven ABC in complex and dynamic environments: a simulation analysis

OpenAIRE

S. HOOZÉE; M. VANHOUCKE; W. BRUGGEMAN; -

2010-01-01

This paper compares the accuracy of traditional ABC and time-driven ABC in complex and dynamic environments through simulation analysis. First, when unit times in time-driven ABC are known or can be flawlessly estimated, time-driven ABC coincides with the benchmark system and in this case our results show that the overall accuracy of traditional ABC depends on (1) existing capacity utilization, (2) diversity in the actual mix of productive work, and (3) error in the estimated percentage mix. ...

Accuracy of the ABC/2 Score for Intracerebral Hemorrhage: Systematic Review and Analysis of MISTIE, CLEAR-IVH, and CLEAR III.

Science.gov (United States)

Webb, Alastair J S; Ullman, Natalie L; Morgan, Tim C; Muschelli, John; Kornbluth, Joshua; Awad, Issam A; Mayo, Stephen; Rosenblum, Michael; Ziai, Wendy; Zuccarrello, Mario; Aldrich, Francois; John, Sayona; Harnof, Sagi; Lopez, George; Broaddus, William C; Wijman, Christine; Vespa, Paul; Bullock, Ross; Haines, Stephen J; Cruz-Flores, Salvador; Tuhrim, Stan; Hill, Michael D; Narayan, Raj; Hanley, Daniel F

2015-09-01

The ABC/2 score estimates intracerebral hemorrhage (ICH) volume, yet validations have been limited by small samples and inappropriate outcome measures. We determined accuracy of the ABC/2 score calculated at a specialized reading center (RC-ABC) or local site (site-ABC) versus the reference-standard computed tomography-based planimetry (CTP). In Minimally Invasive Surgery Plus Recombinant Tissue-Type Plasminogen Activator for Intracerebral Hemorrhage Evacuation-II (MISTIE-II), Clot Lysis Evaluation of Accelerated Resolution of Intraventricular Hemorrhage (CLEAR-IVH) and CLEAR-III trials. ICH volume was prospectively calculated by CTP, RC-ABC, and site-ABC. Agreement between CTP and ABC/2 was defined as an absolute difference up to 5 mL and relative difference within 20%. Determinants of ABC/2 accuracy were assessed by logistic regression. In 4369 scans from 507 patients, CTP was more strongly correlated with RC-ABC (r(2)=0.93) than with site-ABC (r(2)=0.87). Although RC-ABC overestimated CTP-based volume on average (RC-ABC, 15.2 cm(3); CTP, 12.7 cm3), agreement was reasonable when categorized into mild, moderate, and severe ICH (κ=0.75; PABC (84% within 5 mL; 48% of scans within 20%) than for site-ABC (81% within 5 mL; 41% within 20%). RC-ABC had moderate accuracy for detecting ≥5 mL change in CTP volume between consecutive scans (sensitivity, 0.76; specificity, 0.86) and was more accurate with smaller ICH, thalamic hemorrhage, and homogeneous clots. ABC/2 scores at local or central sites are sufficiently accurate to categorize ICH volume and assess eligibility for the CLEAR-III and MISTIE III studies and moderately accurate for change in ICH volume. However, accuracy decreases with large, irregular, or lobar clots. URL: http://www.clinicaltrials.gov. Unique identifier: MISTIE-II NCT00224770; CLEAR-III NCT00784134. © 2015 American Heart Association, Inc.

77 FR 15368 - 2012 Annual Meeting of the Ozone Transport Commission

Science.gov (United States)

2012-03-15

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9647-5] 2012 Annual Meeting of the Ozone Transport Commission... Environmental Protection Agency is announcing the 2012 Annual Meeting of the Ozone Transport Commission (OTC... such as performance standards for electric generating units (EGUs) on high electric demand days, oil...

78 FR 25265 - 2013 Annual Meeting of the Ozone Transport Commission

Science.gov (United States)

2013-04-30

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9806-5] 2013 Annual Meeting of the Ozone Transport Commission... Environmental Protection Agency is announcing the 2013 Annual Meeting of the Ozone Transport Commission (OTC... such as performance standards for electric generating units (EGUs) on high electric demand days, oil...

FERMILAB Annual Users' Meeting

International Nuclear Information System (INIS)

Anon.

1983-01-01

In an atmosphere full of promise a record 370 users met at Fermilab in April for the 15th annual Users' Meeting. The gathering took place in the midst of activities to bring beam through one-third of the Energy Saver. Laboratory Director Leon Lederman and his staff reported that the ring was nearing completion and that circulating beam could follow soon

ACPSEM (NZ Branch) annual meeting

International Nuclear Information System (INIS)

McEwan, A.C.

1999-01-01

The 1998 annual meeting of the New Zealand Branch of the Australasian College of Physical Scientists and Engineers in Medicine was held at the Christchurch School of Medicine over 26-27 November 1998, and attracted a record number of around 45 registrations. The meeting serves a number of purposes but one of the primary ones is to bring together scientists in medicine from around the country to compare notes on practices and advances, particularly in radiotherapy and diagnostic radiology physics. Following the meeting format established over recent years, separate workshops were devoted to radiotherapy physics and developments in the regional centres represented, and to practical issues relating to medical physics in diagnostic radiology. The workshops were held in parallel with presentations of scientific papers covering a wide range of topics, but with about half relating to engineering applications in medicine. (author)

ABC Kinga kauplused = ABC King shoe stores

Index Scriptorium Estoniae

2011-01-01

Tallinnas Kristiine keskuses, Tartu Kaubamajas ja Pärnus Port Artur 2 asuvate ABC Kinga kaupluste sisekujundusest. Sisearhitekid Andres Labi ja Janno Roos (Ruumilabor OÜ), loetletud nende ühiselt tehtud töid

Publication rate of abstracts presented at the 2010 Canadian Ophthalmological Society Annual Meeting.

Science.gov (United States)

Basilious, Alfred; Benavides Vargas, Ana Maria; Buys, Yvonne M

2017-08-01

To evaluate the publication rate of submitted abstracts accepted for presentation at the 2010 Canadian Ophthalmological Society (COS) Annual Meeting in peer-reviewed journals. A retrospective analysis and literature search of abstracts presented at the 2010 COS Annual Meeting. Abstracts accepted as an oral presentation or poster from the 2010 COS Annual Meeting were tabulated by type of presentation (oral vs poster), subspecialty, study design, number of authors, and principal investigator's institution. A PubMed search was conducted for each abstract by key word, first author, and last author. The year of publication, journal, and impact factor were recorded for identified publications. Publication rate was calculated by type of presentation, subspecialty, study design, number of authors, and institution. A total of 175 abstracts were presented at the 2010 COS Annual Meeting. There were 105 oral (60%) and 70 poster (40%) presentations. The overall publication rate was 45.7%; 49.5% for oral presentations and 40.0% for posters. Cornea (57.6%) and public health (54.5%) had the highest publication rates of all subspecialties. Randomized control trials (71.4%) and cohort studies (70.0%) had higher publication rates than other study designs. Overall, 28.8% of abstracts were published in the Canadian Journal of Ophthalmology. The average impact factor of all publications was 2.73. Of abstracts presented at the 2010 COS Annual Meeting, 45.7% were published within 5 years after the conference. This publication rate is within the upper end of previously reported meeting publication rates for medical societies. Copyright © 2017 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

China Mobile Phone Industry CEO Annual Meeting Opening in November

Institute of Scientific and Technical Information of China (English)

无

2006-01-01

@@ 2006 China Mobile Phone Industry CEO Annual Meeting (www.cmqc.org.cn) will open at Beijing State Guest Hotel On November 1. By that time, over 300 CEO will gather there to contend about the theme of this annual meeting "The World Competitiveness of China Mobile Industry Right Territory", view the unforgettable evening of "2006 Wisdom Sharing Brainstorming, 2007 Perspective Plan Hand in Hand".

Book of abstracts. Thirty ninth annual scientific meeting

International Nuclear Information System (INIS)

2009-04-01

The 39 th Annual Scientific Meeting of the Australian and New Zealand Society of Nuclear Medicine was held in Sydney, Australia. The Meeting was held from Thursday, 23 April to Monday, 27 April at the Sydney Convention and Exhibition Centre in Darling Harbour and the theme was Multimodality - Here and Now.

78 FR 23960 - Annual Public Meeting

Science.gov (United States)

2013-04-23

... annual open public meeting. The Foundation will provide an overview of its history, project updates, as... p.m. Time allotted for each registrant will be 3 minutes. The contact person will notify interested... individuals interested in making formal comments should notify the contact person and submit a brief statement...

Annual technical meeting of the NRC cooperative severe accident research program

International Nuclear Information System (INIS)

Silver, E.G.

1993-01-01

This brief report summarizes the 1992 annual technical meeting of the NRC Cooperative Severe Accident Research Program (CSARP-92) held at the Hyatt Regency Hotel in Bethesda, Maryland, May 4-8, 1992. The report is taken mainly from coverage of the meeting published in the June 5, 1992, issue of Atomic Energy Clearinghouse. Results of this meeting are formalized at the Water Reactor Safety Information Meetings (WRSIM) that are held annually in October. Nuclear Safety summarizes the annual WRSIM meetings and provides a list of the presentations that were given. Interested readers are encouraged to review listed topics to identify specific topic areas in severe accident research. Sessions were held on in-vessel core melt progression; fuel-coolant interactions; fission-product behavior; direct containment heating; and severe accident code development, assessment, and validation. Summaries of the individual technical sessions and the current state of the art in these areas were given by the chairmen

Don't Miss the Meeting: Arthroscopy Association of North America Annual Scientific Meeting Reveals Timely and Unique Content.

Science.gov (United States)

Lubowitz, James H; Brand, Jefferson C; Provencher, Matthew T; Rossi, Michael J

2017-04-01

The Annual Meeting of the Arthroscopy Association of North America (AANA) is notable for timely presentation of innovative research and development. In addition, much of what is presented at the Annual Meeting is never published in Arthroscopy journal. Readers are encouraged to attend the AANA meeting to keep up with the discussion and debate. Copyright © 2017 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

Isolation and Characterization of the Colletotrichum acutatum ABC Transporter CaABC1

Directory of Open Access Journals (Sweden)

Suyoung Kim

2014-12-01

Full Text Available Fungi tolerate exposure to various abiotic stresses, including cytotoxic compounds and fungicides, via their ATP-driven efflux pumps belonging to ATP-binding cassette (ABC transporters. To clarify the molecular basis of interaction between the fungus and various abiotic stresses including fungicides, we constructed a cDNA library from germinated conidia of Colletotrichum acutatum, a major anthracnose pathogen of pepper (Capsicum annum L.. Over 1,000 cDNA clones were sequenced, of which single clone exhibited significant nucleotide sequence homology to ABC transporter genes. We isolated three fosmid clones containing the C. acutatum ABC1 (CaABC1 gene in full-length from genomic DNA library screening. The CaABC1 gene consists of 4,059 bp transcript, predicting a 1,353-aa protein. The gene contains the typical ABC signature and Walker A and B motifs. The 5′-flanking region contains a CAAT motif, a TATA box, and a Kozak region. Phylogenetic and structural analysis suggested that the CaABC1 is a typical ABC transporter gene highly conserved in various fungal species, as well as in Chromista, Metazoans, and Viridiplantae. We also found that CaABC1 was up-regulated during conidiation and a minimal medium condition. Moreover, CaABC1 was induced in iprobenfos, kresoxim-methyl, thiophanate-methyl, and hygromycin B. These results demonstrate that CaABC1 is necessary for conidiation, abiotic stress, and various fungicide resistances. These results will provide the basis for further study on the function of ABC transporter genes in C. acutatum.

Assessment of the ABC/2 Method of Epidural Hematoma Volume Measurement as Compared to Computer-Assisted Planimetric Analysis.

Science.gov (United States)

Hu, Ting-Ting; Yan, Ling; Yan, Peng-Fei; Wang, Xuan; Yue, Ge-Fen

2016-01-01

Epidural hematoma volume (EDHV) is an independent predictor of prognosis in patients with epidural hematoma (EDH) and plays a central role in treatment decision making. This study's objective was to determine the accuracy and reliability of the widely used volume measurement method ABC/2 in estimating EDHV by comparing it to the computer-assisted planimetric method. A data set of computerized tomography (CT) scans of 35 patients with EDH was evaluated to determine the accuracy of ABC/2 method, using computer-assisted planimetric technique to establish the reference criterion of EDHV for each patient. Another data set was constructed by randomly selecting 5 patients then replicating each case twice to yield 15 patients. Intra- and interobserver reliability were evaluated by asking four observers to independently estimate EDHV for the latter data set using the ABC/2 method. Estimation of EDHV using the ABC/2 method showed high intra- and interobserver reliability (intra-class correlation coefficient = .99). These estimates were closely correlated with planimetric measures (r = .99). But the ABC/2 method generally overestimated EDHV, especially in the nonellipsoid-like group. The difference between the ABC/2 measures and planimetric measures was statistically significant (p ABC/2 method could be used for EDHV measurement, which would contribute to treatment decision making as well as clinical outcome prediction. However, clinicians should be aware that the ABC/2 method results in a general volume overestimation. Future studies focusing on justification of the technique to improve its accuracy would be of practical value. © The Author(s) 2015.

Israel Geological Society, annual meeting 1994

International Nuclear Information System (INIS)

Amit, R.; Arkin, Y.; Hirsch, F.

1994-02-01

The document is a compilation of papers presented during the annual meeting of Israel Geological Society. The document is related with geological and environmental survey of Israel. It discusses the technology and instruments used to carry out such studies. Main emphasis is given to seismology, geochemical analysis of water, water pollution and geophysical survey of rocks

47th Annual Meeting of the Academy

Indian Academy of Sciences (India)

Proceedings and to give Fellows a general idea of the work done in India in ... can be classified as very good and the decrease in the number of ..... It would be a great service to mathematics, .... ordinary course of events, the Annual Meeting.

Fourteenth Annual Meeting of the International Working Group on Past Reactors. Summary Report. Part I

International Nuclear Information System (INIS)

1981-11-01

The Fourteenth Annual Meeting of the IAEA-IWGFR was held in accordance with the recommendations of the previous Annual Group Meeting, at the Vienna International Centre, Vienna from 31 March to 3 April 1981. All Member States of the group were represented at the meeting: France, the Federal Republic of Germany, India, Italy, Japan, the Union of Soviet Socialist Republics, the United Kingdom and the United States of America. The meeting was also attended by representatives from the Commission of European Communities, the Nuclear Energy Agency of the Organisation for Economic Co-operation and Development, the International Atomic Energy Agency and observers from Switzerland. The Agenda of the Meeting was as follows: 1. Review of IWGFR activities; 2. Consideration of future method of operation of the IWGFR; 3. Consideration of Conferences on Fast Reactors; 4. Consideration of the major recommendations of some of the IWGFR specialists' meetings for which the support of the IWGFR is requested; 5. Consideration of a schedule for specialists' meetings in 1981-1982; 6. Presentations and discussions on national programmes on fast breeder reactors.; 7. Recommendation of the IWGFR regarding a request of Switzerland concerning participation in the IWGFR; 8. The date and place of the Fifteenth Annual Meeting of the IWGFR

78 FR 79674 - Gulf of Mexico Fishery Management Council; Public Meeting

Science.gov (United States)

2013-12-31

... Limits Monitoring Overview 5. Red Snapper Slot Limit Analysis 6. Alternative Red Snapper ABCs a. based on...: The Gulf of Mexico Fishery Management Council (Council) will hold a meeting of the ABC Control Rule... the individual meeting agendas are as follows: ABC Control Rule Working Group Agenda, Wednesday...

45 CFR 263.1 - How much State money must a State expend annually to meet the basic MOE requirement?

Science.gov (United States)

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false How much State money must a State expend annually... State's Maintenance of Effort? § 263.1 How much State money must a State expend annually to meet the... historic State expenditures. (2) However, if a State meets the minimum work participation rate requirements...

www.kerntechnik.info = annual meeting on nuclear technology on the web

International Nuclear Information System (INIS)

Anon.

2009-01-01

The ANNUAL MEETING ON NUCLEAR TECHNOLOGY can be found under the new Internet address of www.kerntechnik.info as of now. The Web site offers systematic access to all important information and features about this largest European specialized meeting of its kind. Pages showing the program of the Conference with its plenary session, topical sessions, technical sessions, and the ''Nuclear Power Campus'' and ''Competency Workshop'' special events, are updated continuously. In addition, contributions to the technical sessions may be submitted on line at an early point in time; registrating for the meeting as well as booking hotel accommodation are also possible on line. The next ANNUAL MEETING ON NUCLEAR TECHNOLOGY will be held at the Berlin Congress Center in Berlin/Germany on May 4-6, 2010. (orig.)

Similarities and dissimilarities between the movement ABC-2 and the Zurich neuromotor assessment in children with suspected developmental coordination disorder.

Science.gov (United States)

Kakebeeke, Tanja H; Egloff, Kristin; Caflisch, Jon; Chaouch, Aziz; Rousson, Valentin; Largo, Remo H; Jenni, Oskar G

2014-11-01

An established tool for the assessment of motor performance in children with developmental coordination disorder (DCD) is the Movement-ABC-2 (M-ABC-2). The Zurich Neuromotor Assessment (ZNA) is also widely used for the evaluation of children's motor performance, but has not been compared with the M-ABC-2. Fifty-one children (39 males) between 5 and 7 years of age with suspected DCD were assessed using the M-ABC-2 and the ZNA. Rank correlations between scores of different test components were calculated. The structure of the tests was explored using canonical-correlation analysis. The correlation between total scores of the two motor tests was reasonable (0.66; pABC-2, due to poor performance in the fine motor adaptive component and increased contralateral associated movements (CAM). The canonical-correlation analysis revealed that ZNA measures components like pure motor skills and CAM that are not represented in the M-ABC-2. Furthermore, there was also no equivalent for the aiming and catching items of the M-ABC-2 in ZNA. The two tests measure different motor characteristics in children with suspected DCD and, thus, can be used complementary for the diagnosis of the disorder. Copyright © 2014. Published by Elsevier Ltd.

Sixteenth annual meeting of the International Working Group on Fast Reactors. Summary report

Energy Technology Data Exchange (ETDEWEB)

NONE

1983-10-01

The Sixteenth Annual Meeting of the IWGFR was held in accordance with the recommendation of the previous Annual Meeting Group, in Vienna from 12-15 April 1983. The meeting was attended by the Member States of the group: France, the Federal Republic of Germany, Italy, Japan, the United Kingdom, and the USA, as well as by representatives from CEC, IAEA and OECD and observer from the USSR. This document includes: review of the IWGFR Activities for the period since the Eleventh Annual Meeting of the Group; preliminary programme of international conference on breeder reactors as a world energy resource and the breeder fuel cycle; list of meetings on atomic energy which may be of interest to the IWGFR Members; IWGFR criteria for supporting some of the international conferences; list of proposed topics for the IWGFR Specialists' Meetings; list of topics for review articles on LMFBR recommended for publication by the IAEA; list of meetings sponsored by the IWGFR; a list of members of the International Working Group on Fast Reactors.

Sixteenth annual meeting of the International Working Group on Fast Reactors. Summary report

International Nuclear Information System (INIS)

1983-10-01

The Sixteenth Annual Meeting of the IWGFR was held in accordance with the recommendation of the previous Annual Meeting Group, in Vienna from 12-15 April 1983. The meeting was attended by the Member States of the group: France, the Federal Republic of Germany, Italy, Japan, the United Kingdom, and the USA, as well as by representatives from CEC, IAEA and OECD and observer from the USSR. This document includes: review of the IWGFR Activities for the period since the Eleventh Annual Meeting of the Group; preliminary programme of international conference on breeder reactors as a world energy resource and the breeder fuel cycle; list of meetings on atomic energy which may be of interest to the IWGFR Members; IWGFR criteria for supporting some of the international conferences; list of proposed topics for the IWGFR Specialists' Meetings; list of topics for review articles on LMFBR recommended for publication by the IAEA; list of meetings sponsored by the IWGFR; a list of members of the International Working Group on Fast Reactors

Eighth annual meeting, Vienna, Austria, 15-18 April 1975. Summary report. Part III

International Nuclear Information System (INIS)

1976-01-01

The Summary Report of the Eighth Annual Meeting of the International Working Group on Fast Reactors contains the minutes of the meeting (Part 1); papers which review the national programmes in the field of LMFBRs (Part 2) and the discussions on the review of national programmes (Part 3). The agenda of the meeting involved design, construction, operating experiences of demonstration fast power reactors, reprocessing of spent fuel from LMFBRs, reliability of decay heat removal systems, fuel failure mechanisms, safety of LMFBRs

Eighth annual meeting, Vienna, Austria, 15-18 April 1975. Summary report. Part III

Energy Technology Data Exchange (ETDEWEB)

NONE

1976-01-01

The Summary Report of the Eighth Annual Meeting of the International Working Group on Fast Reactors contains the minutes of the meeting (Part 1); papers which review the national programmes in the field of LMFBRs (Part 2) and the discussions on the review of national programmes (Part 3). The agenda of the meeting involved design, construction, operating experiences of demonstration fast power reactors, reprocessing of spent fuel from LMFBRs, reliability of decay heat removal systems, fuel failure mechanisms, safety of LMFBRs.

Eighth annual meeting, Vienna, Austria, 15-18 April 1975. Summary report. Part I

Energy Technology Data Exchange (ETDEWEB)

NONE

1975-08-01

The Summary Report of the Eighth Annual Meeting of the International Working Group on Fast Reactors contains the minutes of the meeting (Part 1); papers which review the national programmes in the field of LMFBRs (Part 2) and the discussions on the review of national programmes (Part 3). The agenda of the meeting involved design, construction, operating experiences of demonstration fast power reactors, reprocessing of spent fuel from LMFBRs, reliability of decay heat removal systems, fuel failure mechanisms, safety of LMFBRs.

Eighth annual meeting, Vienna, Austria, 15-18 April 1975. Summary report. Part I

International Nuclear Information System (INIS)

1975-08-01

The Summary Report of the Eighth Annual Meeting of the International Working Group on Fast Reactors contains the minutes of the meeting (Part 1); papers which review the national programmes in the field of LMFBRs (Part 2) and the discussions on the review of national programmes (Part 3). The agenda of the meeting involved design, construction, operating experiences of demonstration fast power reactors, reprocessing of spent fuel from LMFBRs, reliability of decay heat removal systems, fuel failure mechanisms, safety of LMFBRs

Abc1: a new ABC transporter from the fission yeast Schizosaccharomyces pombe

DEFF Research Database (Denmark)

Christensen, P U; Davis, K; Nielsen, O

1997-01-01

We have isolated the abc1 gene from the fission yeast Schizosaccharomyces pombe. Sequence analysis suggests that the Abc1 protein is a member of the ABC superfamily of transporters and is composed of two structurally homologous halves, each consisting of a hydrophobic region of six transmembrane...

76 FR 26720 - 2011 Annual Meeting of the Ozone Transport Commission

Science.gov (United States)

2011-05-09

..., Washington, DC 20001; (202) 508-3840; e-mail: [email protected] ; Web site: http://www.otcair.org...) 508-3840; by e-mail: [email protected] or via the OTC Web site at http://www.otcair.org . Dated: April... ENVIRONMENTAL PROTECTION AGENCY [FRL-9303-2] 2011 Annual Meeting of the Ozone Transport Commission...

2011 annual meeting on nuclear technology fully on line

International Nuclear Information System (INIS)

Anon.

2010-01-01

The 2010 ANNUAL MEETING ON NUCLEAR TECHNOLOGY, in its familiar structure of 3 days of conferencing about topics from politics, economy, and technology, was the forum for presentations and discussions in the field of nuclear power. Participants accepted the new concept. This was borne out in particular by the great interest shown in the pre-conference evening with its keynote address, but also by the success of the plenary day, which included a press forum and a panel discussion as components of active communication making the plenary day much more attractive. The 2011 Annual Meeting on Nuclear Technology will be held again at the Berlin Congress Center (bcc) in Alexanderplatz on May 17-19. From September 1, some first important information is available under www.kerntechnik.info, for instance, the call for Papers. All other information about the program will be published in due course. All steps of importance to participants, from registration for the meeting to booking hotel accommodation, can be handled online. (orig.)

2016 Annual Meeting of the German Human Factors and Ergonomics Society

CERN Document Server

Duckwitz, Sönke; Flemisch, Frank; Frenz, Martin; Kuz, Sinem; Mertens, Alexander; Mütze-Niewöhner, Susanne

2017-01-01

These proceedings summarize the best papers in each research area represented at the 2016 Annual Meeting of the German Human Factors and Ergonomics Society, held at Institute of Industrial Engineering and Ergonomics of RWTH Aachen University from March 2-4. The meeting featured more than 200 presentations and 36 posters reflecting the diversity of subject matter in the field of human and industrial engineering. This volume addresses human factors and safety specialists, industrial engineers, work and organizational psychologists, occupational medicines as well as production planners and design engineers.

41st Annual Meeting of the Spanish Nuclear Society

Energy Technology Data Exchange (ETDEWEB)

NONE

2015-07-01

The Spanish Nuclear Society (SNE) is a non-profit association, made up of professionals and institutions, in order to promote awareness and dissemination of nuclear science and technology. The 41 Annual Meeting of the Spanish Nuclear Society was held in A Coruña from 23 to 25 September 2015. This Annual Meeting allows professionals and companies in the sector to analyze the current state of nuclear energy and its future challenges, covering different topics from engineering to R & D, nuclear safety, also impact on health and the environment, climate change, nuclear facilities, experience spanish companies in the management of knowledge in the nuclear sector. This congress has involved some 600 experts who have dealt with current issues and maximum interest.

A Short Proof of Euler's Inequality R ≥ 2r Theorem. Let ∆ ABC be an ...

Indian Academy of Sciences (India)

IAS Admin

A Short Proof of Euler's Inequality R ≥ 2r. Theorem. Let ∆ ABC be an arbitrary triangle with circumradius R and inradius r. Then R ≥ 2r with equality holding if and only if ∆ABC is equilateral. This was first published by Euler in 1765. Since then several proofs have followed, some geometric and some algebraic. We will use ...

AACR Annual Meeting 2008: Autophagy in the forefront of cancer research.

Science.gov (United States)

Karantza, Vassiliki

2008-07-01

The 2008 American Association for Cancer Research (AACR) Annual Meeting was held in San Diego, CA, April 12-16, 2008 (http:// www.aacr.org/home/scientists/meetings--workshops/annual-meeting-2008.aspx). More than 17,000 scientists from 60 countries participated in this meeting that was organized by AACR, the oldest and largest organization in the world focused on cancer research. The scientific presentations included more than 6,000 abstracts and 500 invited talks on new and significant discoveries in basic, clinical, and translational cancer research. Autophagy, as pertaining to tumorigenesis and response to anticancer therapies, was undoubtedly a "hot topic" in this meeting. An educational session, a forum, a minisymposium and several other talks dispersed in different sessions had a strong focus on autophagy. All autophagy-related presentations were very well attended and stimulated lively discussions, clearly indicating that the scientific community is greatly interested in this rapidly-progressing area of research.

Comparing the results of DAADD and ABC of children included in autism spectrum disorders.

Science.gov (United States)

Barbosa, Milene Rossi Pereira; Fernandes, Fernanda Dreux Miranda

2014-01-01

To verify if there are characteristic behaviors of the different diagnosis included in the autism spectrum according to the Differential Assessment of Autism and Other Developmental Disorders (DAADD) and to the Autism Behavior Checklist (ABC). Participants were 45 individuals and their respective speech-language therapists. All therapists are graduate students working with the children for at least 1 year. This time was considered sufficient to the therapists to have the information required by the DAADD questionnaire. It is comprised by 3 protocols specifically designed to children with 2 to 4 years, 4 to 6 years and 6 to 8 years, the same criteria used to separate the research groups, G1, G2 and G3, respectively. Data referring to the ABC were retrieved from the subject's files at the Laboratório de Investigação Fonoaudiológica nos Distúrbios do Espectro do Autismo (Research Laboratory on Language Disorders in the Autism Spectrum) of the School of Medicine, Universidade de São Paulo, where it is routinely applied during the annual assessment. Answers to the different areas of DAADD are similar to the different areas of ABC. These data show data the diagnosis by DAADD is easier in older children. Although there is no significant difference, the large occurrence of Rett's syndrome diagnosis according to the DAADD was associated to higher risk for autism according to the ABC in G1. With increasing age this tendency decreases and either in G2 and G3 Autism is the most frequent diagnosis. Although the results of both questionnaires tend to agree more with increasing age, the DAADD is more sensitive in the different ages while the ABC if more specific only to older children.

Factors predicting publication of sexual medicine abstracts presented at the annual meeting of the American Urological Association.

Science.gov (United States)

Berookhim, Boback M; Kaya, Yekta; Deveci, Serkan; Nelson, Christian J; Mulhall, John P

2013-10-01

At sexual medicine meetings throughout the world, hundreds of scientific abstracts are presented each year. To our knowledge, no previous studies have looked at the rate of publication of these studies in a peer-reviewed journal. To define the fate of abstracts presented at sexual medicine sessions at the annual meeting of the American Urological Association (AUA) and to describe the factors predicting ultimate publication in scientific journals. All abstracts presented at the 2006 and 2007 AUA annual meeting were surveyed to find sexual medicine abstracts. Publication status as of October 2009 was assessed using the Medline database. Abstract parameters were recorded including number of authors, country of origin, clinical or basic research, and area of sexual research. Predictors of publication were analyzed using a multivariable model. Publication status of all sexual medicine abstracts presented at the 2006 and 2007 AUA annual meetings. A total of 208 sexual medicine abstracts were presented in 2006 and 2007. Fifty-one percent of these were published by October 2009. On univariate analysis, the predictors of publication in a peer-reviewed journal included the number of authors (r=0.22, Pacademic centers (RR 2.7, CI 1.7-4.3, Pacademic center (OR 5.9, CI 2.8-12.7, Pmedicine abstracts presented at the 2006 and 2007 annual AUA meetings have been published within 2 to 3 years of the date of presentation. Studies originating from academic centers were six times more likely to be published in a peer-reviewed journal. © 2013 International Society for Sexual Medicine.

ABC and VED Analysis of the Pharmacy Store of a Tertiary Care Teaching, Research and Referral Healthcare Institute of India.

Science.gov (United States)

Devnani, M; Gupta, Ak; Nigah, R

2010-04-01

The ABC and VED (vital, essential, desirable) analysis of the pharmacy store of Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India, was conducted to identify the categories of items needing stringent management control. The annual consumption and expenditure incurred on each item of pharmacy for the year 2007-08 was analyzed and inventory control techniques, i.e. ABC, VED and ABC-VED matrix analysis, were applied. The drug formulary of the pharmacy consisted of 421 items. The total annual drug expenditure (ADE) on items issued in 2007-08 was Rs. 40,012,612. ABC analysis revealed 13.78%, 21.85% and 64.37% items as A, B and C category items, respectively, accounting for 69.97%, 19.95% and 10.08% of ADE of the pharmacy. VED analysis showed 12.11%, 59.38% and 28.51% items as V, E, and D category items, respectively, accounting for 17.14%, 72.38% and 10.48% of ADE of the pharmacy. On ABC-VED matrix analysis, 22.09%, 54.63% and 23.28% items were found to be category I, II and III items, respectively, accounting for 74.21%, 22.23% and 3.56% of ADE of the pharmacy. The ABC and VED techniques need to be adopted as a routine practice for optimal use of resources and elimination of out-of-stock situations in the hospital pharmacy.

International Working Group on Fast Reactors Sixth Annual Meeting. Summary Report

International Nuclear Information System (INIS)

1973-01-01

The Agenda of the Meeting was as follows: 1. Review of IWGFR Activities - 1a. Approval of the minutes of the Fifth IWGFR Meeting. 1b. Report by Scientific Secretary regarding the activities of the Group. 2. Comments on National Programmes on Fast Breeder Reactors. 3. International Coordination of the Schedule for Major Fast Reactor Meetings and other major international meetings having a predominant fast reactor interest. 4. Consideration of Conferences on Fast Reactors. 4a. IAEA Symposium on Fuel and Fuel Elements for Fast Reactors, Brussels, Belgium 2-6 July 1973. 4b. International Symposium on Physics of Fast Reactors, Tokyo, Japan, 16 to 23 October 1973. 4c. International Conference on Fast Reactor Power Stations, London, UK, 11 to 14 March 1974 . 4d. Suggestions of the IWGFR members on other conferences. 5. Consideration of a Schedule for Specialists' Meetings in 1973-74. 6. Other Business - 6a. First-aid in Sodium Burns. 6b. Principles of Good Practice for Safe Operation of Sodium Circuits. 6c. Bibliography on Fast Reactors. 7. The Date and Place of the Seventh Annual Meeting of the IWGFR

Playware ABC 2: a Disruptive Technology for Global Development

DEFF Research Database (Denmark)

Lund, Henrik Hautop

2017-01-01

, anytime. The paper gives examples of how playware becomes a disruptive technology for global development, for instance in the health sector. For instance, in Tanzania doctors and community-based rehabilitation workers are constructing and combining modular playware tiles to easily create the right kind......The Playware ABC concept is used to create solutions that are usable by all kinds of users and contexts in our globalized society. In this paper, the Playware ABC can be exemplified with the development of the modular interactive tiles for health prevention and rehabilitation of anybody, anywhere...

Investing in self-reliance: IDRC's fourth annual public meeting ...

International Development Research Centre (IDRC) Digital Library (Canada)

2016-04-15

Apr 15, 2016 ... Investing in self-reliance: IDRC's fourth annual public meeting ... to advance the Government of Canada's priorities in international development, in areas ... Flexible intellectual property rights lead to greater innovation in Africa.

The annual ASCI meeting: does nostalgia have a future?

Science.gov (United States)

Lefkowitz, Robert J

2008-04-01

For many academic physician-scientists, the yearly Tri-Societies meeting of the ASCI, AAP, and AFCR during the 1960s, '70s, and '80s was an annual rite of spring and the focal point of the academic year. In this brief essay, I set down some miscellaneous recollections of these meetings and some thoughts about why they were of such central importance in the careers of those of my generation.

75 FR 63147 - New England Fishery Management Council; Public Meeting

Science.gov (United States)

2010-10-14

... (ABC) limits. For the Northern Management Area (NMS), the recommended ABC is below the Annual Catch... will review the Plan Development Team's analysis of alternative ACTs and specifications prior to the...

26th Annual ESNA/IUR Meeting: Soil-Plant Relationships

International Nuclear Information System (INIS)

Gerzabek, M. H.

1996-11-01

The radioecological session of the 26 th annual meeting of ESNA (in Busteni/Romania) is for INIS interesting. The session was a joint session with the soil-to-plant transfer working group of the IUR. (Botek)

Proceedings of the fourth annual participants' information meeting, DOE Low-Level Waste Management Program

International Nuclear Information System (INIS)

Large, D.E.; Mezga, L.J.; Stratton, L.E.; Rose, R.R.

1982-10-01

The Fourth Annual Participants' Information Meeting of the Department of Energy Low-Level Waste Management Program was held in Denver, Colorado, August 31 to September 2, 1982. The purpose of the meeting was to report and evaluate technology development funded by the program and to examine mechanisms for technology transfer. The meeting consisted of an introductory plenary session, followed by two concurrent overview sessions and then six concurrent technical sessions. There were two group meetings to review the findings of the technical sessions. The meeting concluded with a plenary summary session in which the major findings of the meeting were addressed. All papers have been abstracted and indexed for the Energy Data Base

Inventory and analysis of ATP-binding cassette (ABC) systems in Brugia malayi.

Science.gov (United States)

Ardelli, B F; Stitt, L E; Tompkins, J B

2010-07-01

ABC systems are one of the largest described protein superfamilies. These systems have a domain organization that may contain 1 or more transmembrane domains (ABC_TM1F) and 1 or 2 ATP-binding domains (ABC_2). The functions (e.g., import, export and DNA repair) of these proteins distinguish the 3 classes of ABC systems. Mining and PCR-based cloning were used to identify 33 putative ABC systems from the Brugia malayi genome. There were 31 class 2 genes, commonly called ABC transporters, and 2 class 3 genes. The ABC transporters were divided into subfamilies. Three belonged to subfamily A, 16 to subfamily B, 5 to subfamily C, 1 to subfamily E and 3 to subfamilies F and G, respectively. None were placed in subfamilies D and H. Similar to other ABC systems, the ABC_2 domain of B. malayi genes was conserved and contained the Walker A and B motifs, the signature sequence/linker region and the switch region with the conserved histidine. The ABC_TM1F domain was less conserved. The relative abundance of ABC systems was quantified using real-time reverse transcription PCR and was significantly higher in female adults of B. malayi than in males and microfilaria, particularly those in subfamilies B and C, which are associated with drug resistance.

Evolutionary relationships of ATP-Binding Cassette (ABC) uptake porters.

Science.gov (United States)

Zheng, Wei Hao; Västermark, Åke; Shlykov, Maksim A; Reddy, Vamsee; Sun, Eric I; Saier, Milton H

2013-05-06

The ATP-Binding Cassette (ABC) functional superfamily includes integral transmembrane exporters that have evolved three times independently, forming three families termed ABC1, ABC2 and ABC3, upon which monophyletic ATPases have been superimposed for energy-coupling purposes [e.g., J Membr Biol 231(1):1-10, 2009]. The goal of the work reported in this communication was to understand how the integral membrane constituents of ABC uptake transporters with different numbers of predicted or established transmembrane segments (TMSs) evolved. In a few cases, high resolution 3-dimensional structures were available, and in these cases, their structures plus primary sequence analyses allowed us to predict evolutionary pathways of origin. All of the 35 currently recognized families of ABC uptake proteins except for one (family 21) were shown to be homologous using quantitative statistical methods. These methods involved using established programs that compare native protein sequences with each other, after having compared each sequence with thousands of its own shuffled sequences, to gain evidence for homology. Topological analyses suggested that these porters contain numbers of TMSs ranging from four or five to twenty. Intragenic duplication events occurred multiple times during the evolution of these porters. They originated from a simple primordial protein containing 3 TMSs which duplicated to 6 TMSs, and then produced porters of the various topologies via insertions, deletions and further duplications. Except for family 21 which proved to be related to ABC1 exporters, they are all related to members of the previously identified ABC2 exporter family. Duplications that occurred in addition to the primordial 3 → 6 duplication included 5 → 10, 6 → 12 and 10 → 20 TMSs. In one case, protein topologies were uncertain as different programs gave discrepant predictions. It could not be concluded with certainty whether a 4 TMS ancestral protein or a 5 TMS ancestral protein

The USCACA hosted symposiums at the 7th CACA annual meeting and the 15th CSCO annual meeting in Beijing.

Science.gov (United States)

Shi, Michael; Yang, Wancai; Qian, Pascal; Yan, Li

2012-11-01

In September 2012, the US Chinese Anti-Cancer Association (USCACA) hosted two symposiums in Beijing. The USCACA hosted the first joint session at the 7th annual meetings of the Chinese Anti-Cancer Association (CACA), themed on "Collaboration between the US and China in Cancer Research." Six experts from the United States and China presented their latest work on basic and translational cancer research. During this symposium, 5 young Chinese scholars, returnees after their training in the United States, were honored the"AFCR-USCACA Scholarships Award." The USCACA hosted a second symposium during the 15th annual meeting of the Chinese Society of Clinical Oncology (CSCO), focused on the "US-China Collaboration in Cancer Drug Clinical Development." An international delegation of oncology experts presented the innovative clinical trial strategies and discussed the biomarkers for cancer early detection and clinical trials, targeted therapy, and new drug development. The Oncology Drug Clinical Development and Safety Evaluation Committee was also launched to promote an innovative environment and to provide a collaborative platform for anti-cancer drug development in China.

86th Annual Georgia Public Health Association Meeting & Conference Report.

Science.gov (United States)

Smith, Selina A; Abbott, Regina; Sims, Christy

2015-01-01

The 86 th annual meeting of the Georgia Public Health Association (GPHA) and joint conference with the Southern Health Association was held in Atlanta, Georgia, on April 13-14, 2015, with pre-conference (April 12 th ) and post-conference (April 14 th ) Executive Board meetings. As Georgia's leading forum for public health researchers, practitioners, and students, the annual meeting of the GPHA brings together participants from across the state to explore recent developments in the field and to exchange techniques, tools, and experiences. Historically, the GPHA conference has been held in Savannah (n=24); Jekyll Island (n=20); Atlanta (n=16); Augusta (n=4); and Gainesville (n=1). There was no annual meeting during the early years (1929-1936); during World War II (1941-1943 and 1945); and for four years during the 1980s. Between 2006 and 2010, GPHA held one-day annual meetings and business sessions with educational workshops. Several new initiatives were highlighted as part of this year's conference. These included a "move and groove" physical activity lounge, registration scholarships for students with a dedicated meet-and-greet reception, an expanded exhibit hall, presentation and approval of three resolutions (related to healthy foods at official activities and events; weapons at official activities and events; and memorials), and approval of the 2015 legislative policy positions and amended association bylaws. The theme for the conference was Advocacy in Action for Public Health . Specifically, the program addressed ensuring access to care; protecting funding for core programs, services, and infrastructure; eliminating health disparities; and addressing key public health issues important to the state of Georgia. One hundred and nine (109) abstracts were submitted for peer review; 36 were accepted for poster and 40 for workshop presentations. Four plenary sessions with keynote speakers covered the intersection between advocacy and policy, Georgia's response to the

Abstracts of Presentations--Seventh Annual 4S Meeting.

Science.gov (United States)

4S - Society for Social Studies of Science, 1982

1982-01-01

Presents abstracts of papers for the Seventh Annual Meeting of the Society for the Social Studies of Science. Topics include, among others, rhetoric of a scientific controversy; recombinant DNA; science and social justice; patent citation analysis; national need and peer-review process; and scientism, romanticism, and social realist images of…

83rd Annual Meeting of the Eastern Psychological Association

Directory of Open Access Journals (Sweden)

I A Novikova

2012-06-01

Full Text Available A brief review of the International Program of the 83rd Annual Meeting of the Eastern Psychological Association (EPA that took place on 1-4 March 2012 in Pittsburgh (USA is submitted in the publication.

Reporting of Uncertainty at the 2013 Annual Meeting of the American Society for Radiation Oncology

International Nuclear Information System (INIS)

Lee, W. Robert

2014-01-01

Purpose: The annual meeting of the American Society for Radiation Oncology (ASTRO) is designed to disseminate new scientific findings and technical advances to professionals. Best practices of scientific dissemination require that some level of uncertainty (or imprecision) is provided. Methods and Materials: A total of 279 scientific abstracts were selected for oral presentation in a clinical session at the 2013 ASTRO Annual Meeting. A random sample of these abstracts was reviewed to determine whether a 95% confidence interval (95% CI) or analogous measure of precision was provided for time-to-event analyses. Results: A sample of 140 abstracts was reviewed. Of the 65 abstracts with Kaplan-Meier or cumulative incidence analyses, 6 included some measure of precision (6 of 65 = 9%; 95% CI, 2-16). Of the 43 abstracts reporting ratios for time-to-event analyses (eg, hazard ratio, risk ratio), 22 included some measure of precision (22 of 43 = 51%; 95% CI, 36-66). Conclusions: Measures of precision are not provided in a significant percentage of abstracts selected for oral presentation at the Annual Meeting of ASTRO

12th Annual ALS Users' Association Meeting

International Nuclear Information System (INIS)

Robinson, Arthur L.

1999-01-01

Science took the front seat as 219 Advanced Light Source (ALS) users and staff gathered on Monday and Tuesday, October 18 and 19 for the twelfth annual users' meeting. The bulk of the meeting was dedicated to reports on science at the ALS. Packed into two busy days were 31 invited oral presentations and 80 submitted poster presentations, as well as time to visit 24 vendor booths. The oral sessions were dedicated to environmental science, chemical dynamics, biosciences, magnetic materials, and atomic and molecular science. In addition, there was an ALS highlights session that emphasized new results and a session comprising highlights from the young scientists who will carry the ALS into the future

Enhancing the ABC Cross

OpenAIRE

Euske, K.J.; Vercio, Alan

2007-01-01

The purpose of the ABC Cross was to portray both a cost and process view of an organization as simply as possible. Unfortunately, the model’s simplified form does not capture the real value of activity-based costing (ABC) for cost accounting that emerged in the mid-1980s. Here we present several ABC models that can help functional and process managers make better decisions.

24th Annual ESNA/IUR Meeting: Soil-Plant Relationships

International Nuclear Information System (INIS)

Gerzabek, M. H.

1994-11-01

The 24 th annual meeting of ESNA was jointly organized with the IUR (International Union of Radioecologists), working group soil-to-plant transfer in Varna, Bulgaria. For INIS interesting is the session 'behaviour of radionuclides in the terrestrial foodchain'. (Botek)

Assessment of the accuracy of ABC/2 variations in traumatic epidural hematoma volume estimation: a retrospective study

Directory of Open Access Journals (Sweden)

Pengfei Yan

2016-04-01

Full Text Available Background. The traumatic epidural hematoma (tEDH volume is often used to assist in tEDH treatment planning and outcome prediction. ABC/2 is a well-accepted volume estimation method that can be used for tEDH volume estimation. Previous studies have proposed different variations of ABC/2; however, it is unclear which variation will provide a higher accuracy. Given the promising clinical contribution of accurate tEDH volume estimations, we sought to assess the accuracy of several ABC/2 variations in tEDH volume estimation. Methods. The study group comprised 53 patients with tEDH who had undergone non-contrast head computed tomography scans. For each patient, the tEDH volume was automatically estimated by eight ABC/2 variations (four traditional and four newly derived with an in-house program, and results were compared to those from manual planimetry. Linear regression, the closest value, percentage deviation, and Bland-Altman plot were adopted to comprehensively assess accuracy. Results. Among all ABC/2 variations assessed, the traditional variations y = 0.5 × A1B1C1 (or A2B2C1 and the newly derived variations y = 0.65 × A1B1C1 (or A2B2C1 achieved higher accuracy than the other variations. No significant differences were observed between the estimated volume values generated by these variations and those of planimetry (p > 0.05. Comparatively, the former performed better than the latter in general, with smaller mean percentage deviations (7.28 ± 5.90% and 6.42 ± 5.74% versus 19.12 ± 6.33% and 21.28 ± 6.80%, respectively and more values closest to planimetry (18/53 and 18/53 versus 2/53 and 0/53, respectively. Besides, deviations of most cases in the former fell within the range of 20% (90.57% and 96.23, respectively. Discussion. In the current study, we adopted an automatic approach to assess the accuracy of several ABC/2 variations for tEDH volume estimation. Our initial results showed that the variations y = 0.5 × A1B1C1 (or A2B2C1

The Bioelectromagnetic Society Thirteenth Annual Meeting 1991: Program and abstracts

Energy Technology Data Exchange (ETDEWEB)

1992-12-31

This volume contains author abstracts representing oral and poster presentations made at the Thirteenth Annual Meeting of The Bioelectromagnetic Society held in Salt Lake City, Utah June 23--27, 1991.

Tolfenamic acid degradation by direct photolysis and the UV-ABC/H2O2 process: factorial design, kinetics, identification of intermediates, and toxicity evaluation.

Science.gov (United States)

de Melo da Silva, Lucas; Pereira Cavalcante, Rodrigo; Fabbro Cunha, Rebeca; Gozzi, Fábio; Falcao Dantas, Renato; de Oliveira, Silvio Cesar; Machulek, Amilcar

2016-12-15

This study employed direct UV-ABC photolysis and the UV-ABC/H 2 O 2 process to investigate the degradation of tolfenamic acid (TA), a common anti-inflammatory drug used in both human and veterinary medicine. A 2 3 factorial design with added center point was used to evaluate the effect of three independent variables-namely, H 2 O 2 concentration ([H 2 O 2 ]), TA concentration ([TA]), and experiment time (time)-on TA degradation and H 2 O 2 photolysis during UV-ABC/H 2 O 2 treatment using a high-pressure mercury vapor lamp (photon flux of 2.6307 × 10 4 J s -1 ) as the UV irradiation source. The responses yielded similar values, revealing a linear behavior, with correlation coefficients R = 0.9968 and R adj = 0.9921 for TA degradation and R = 0.9828 and R adj = 0.9570 for H 2 O 2 photolysis. The most efficient combination of variables was [H 2 O 2 ] = 255 mg L -1 and [TA] = 25 mg L -1 , resulting in 100% TA degradation and 98.87% H 2 O 2 photolysis by 90 min of treatment. Additionally, the second-order kinetic constant of the reaction between TA and HO ● was determined using a competitive kinetic model, employing 2,4-dichlorophenoxyacetic acid (2,4D) as the reference compound. The kinetic constant was 1.9 × 10 10 M -1 s -1 in alkaline medium. TA degradation by direct photolysis generated quinone imines as by-products, responsible for the formation of a dark red "internal filter" that increased the value of acute toxicity to Artemia salina. The UV-ABC/H 2 O 2 process did not promote formation of quinone imines by 90 min of treatment and therefore did not increase acute toxicity values. Several by-products generated during TA degradation were identified and possible degradation pathways for the UV-ABC and UV-ABC/H 2 O 2 processes were proposed. Copyright © 2016 Elsevier B.V. All rights reserved.

50. Annual meeting of the Deutsche Gesellschaft fuer Neuroradiologie. Abstracts

International Nuclear Information System (INIS)

2015-01-01

The volume on the 50th annual meeting of the Deutsche Gesellschaft fuer Neuroradiologie includes the abstracts concerning the following issues: infectious central nervous system diseases, neurodegenerations, infarction, petrosal bone pathology, neurointerventions.

49. Annual meeting of the Deutsche Gesellschaft fuer Neuroradiologie. Abstracts

International Nuclear Information System (INIS)

2014-01-01

The conference proceedings of the 48. Annual meeting of the Deutsche Gesellschaft fuer Neuroradiologie contain abstracts on the following issues: neuro-oncological imaging, multimodal imaging concepts, subcranial imaging, spinal codes, interventional neuroradiology.

Tweeting the Meeting: Twitter Use at The American Society of Breast Surgeons Annual Meeting 2013-2016.

Science.gov (United States)

Attai, Deanna J; Radford, Diane M; Cowher, Michael S

2016-10-01

Twitter social media is being used to disseminate medical meeting information. Meeting attendees and other interested parties have the ability to follow and participate in conversations related to meeting content. We analyzed Twitter activity generated from the 2013-2016 American Society of Breast Surgeons Annual Meetings. The Symplur Signals database was used to determine number of tweets, tweets per user, and impressions for each meeting. The number of unique physicians, patients/caregivers/advocates, and industry participants was determined. Physician tweeters were cross-referenced with membership and attendance rosters. Tweet transcripts were analyzed for content and tweets were categorized as either scientific, social, administrative, industry promotion, or irrelevant. From 2013 to 2016, the number of tweets increased by 600 %, the number of Twitter users increased by 450 %, and the number of physician tweeters increased by 457 %. The number of impressions (tweets × followers) increased from more than 3.5 million to almost 20.5 million, an increase of 469 %. The majority of tweets were informative (70-80 %); social tweets ranged from 13 to 23 %. A small percentage (3-6 %) of tweets were related to administrative matters. There were very few industry or irrelevant tweets. Twitter social media use at the American Society of Breast Surgeons annual meeting showed a substantial increase during the time period evaluated. The use of Twitter during professional meetings is a tremendous opportunity to share information. The authors feel that medical conference organizers should encourage Twitter participation and should be educating attendees on the proper use of Twitter.

Association of engineering geologists 32nd annual meeting

International Nuclear Information System (INIS)

Anon.

1989-01-01

This book contains the proceedings of the 32nd Annual Meeting of the Association of Engineering Geologists. Included are the following articles: Engineering geology---a tool in petroleum exploration ventures font, The soil headspace survey method as an indicator of soil and groundwater contamination by petroleum products, Determination of compressive strength of coal for pillar design hirt

Surface charge-specific interactions between polymer nanoparticles and ABC transporters in Caco-2 cells

Energy Technology Data Exchange (ETDEWEB)

Bhattacharjee, Sourav, E-mail: sourav.bhattacharjee@wur.nl [Wageningen University, Laboratory of Organic Chemistry (Netherlands); Opstal, Edward J. van; Alink, Gerrit M. [Wageningen University, Division of Toxicology (Netherlands); Marcelis, Antonius T. M.; Zuilhof, Han [Wageningen University, Laboratory of Organic Chemistry (Netherlands); Rietjens, Ivonne M. C. M. [Wageningen University, Division of Toxicology (Netherlands)

2013-06-15

The surface charge-dependent transport of polymeric nanoparticles (PNPs) across Caco-2 monolayers grown on transwell culture systems as an in vitro model for intestinal transport was tested. The transport of well-characterized, monodisperse, and fluorescent tri-block copolymer nanoparticles (TCNPs/size {approx}45 nm) and polystyrene nanoparticles (PSNPs/size {approx}50 nm), with different surface charges (positive and negative), was quantified. The positive PNPs showed a higher intracellular uptake and flux across the Caco-2 monolayers than the negative PNPs. Multidrug resistance/P-glycoprotein (MDR1/P-gp), a specific ATP-binding cassette (ABC) transporter, was found to play a major role in the cellular efflux of positive PNPs, whereas the multidrug resistance protein 1 took part in the efflux of negative PNPs from Caco-2 cells. The positive PNPs also caused an increased cellular uptake and apical to basolateral transport of the carcinogen PhIP across the Caco-2 monolayer. The flavonoid quercetin, which is known to interact with ABC transporters, promoted the intracellular uptake of different PNPs and interfered with the normal distribution patterns of PNPs in the transwell system. These results indicate that PNPs display surface charge-specific interactions with ABC transporters and can even affect the bioavailability of toxic food-borne compounds (like pro-carcinogens).

Surface charge-specific interactions between polymer nanoparticles and ABC transporters in Caco-2 cells

Science.gov (United States)

Bhattacharjee, Sourav; van Opstal, Edward J.; Alink, Gerrit M.; Marcelis, Antonius T. M.; Zuilhof, Han; Rietjens, Ivonne M. C. M.

2013-06-01

The surface charge-dependent transport of polymeric nanoparticles (PNPs) across Caco-2 monolayers grown on transwell culture systems as an in vitro model for intestinal transport was tested. The transport of well-characterized, monodisperse, and fluorescent tri-block copolymer nanoparticles (TCNPs/size 45 nm) and polystyrene nanoparticles (PSNPs/size 50 nm), with different surface charges (positive and negative), was quantified. The positive PNPs showed a higher intracellular uptake and flux across the Caco-2 monolayers than the negative PNPs. Multidrug resistance/P-glycoprotein (MDR1/P-gp), a specific ATP-binding cassette (ABC) transporter, was found to play a major role in the cellular efflux of positive PNPs, whereas the multidrug resistance protein 1 took part in the efflux of negative PNPs from Caco-2 cells. The positive PNPs also caused an increased cellular uptake and apical to basolateral transport of the carcinogen PhIP across the Caco-2 monolayer. The flavonoid quercetin, which is known to interact with ABC transporters, promoted the intracellular uptake of different PNPs and interfered with the normal distribution patterns of PNPs in the transwell system. These results indicate that PNPs display surface charge-specific interactions with ABC transporters and can even affect the bioavailability of toxic food-borne compounds (like pro-carcinogens).

Surface charge-specific interactions between polymer nanoparticles and ABC transporters in Caco-2 cells

International Nuclear Information System (INIS)

Bhattacharjee, Sourav; Opstal, Edward J. van; Alink, Gerrit M.; Marcelis, Antonius T. M.; Zuilhof, Han; Rietjens, Ivonne M. C. M.

2013-01-01

The surface charge-dependent transport of polymeric nanoparticles (PNPs) across Caco-2 monolayers grown on transwell culture systems as an in vitro model for intestinal transport was tested. The transport of well-characterized, monodisperse, and fluorescent tri-block copolymer nanoparticles (TCNPs/size ∼45 nm) and polystyrene nanoparticles (PSNPs/size ∼50 nm), with different surface charges (positive and negative), was quantified. The positive PNPs showed a higher intracellular uptake and flux across the Caco-2 monolayers than the negative PNPs. Multidrug resistance/P-glycoprotein (MDR1/P-gp), a specific ATP-binding cassette (ABC) transporter, was found to play a major role in the cellular efflux of positive PNPs, whereas the multidrug resistance protein 1 took part in the efflux of negative PNPs from Caco-2 cells. The positive PNPs also caused an increased cellular uptake and apical to basolateral transport of the carcinogen PhIP across the Caco-2 monolayer. The flavonoid quercetin, which is known to interact with ABC transporters, promoted the intracellular uptake of different PNPs and interfered with the normal distribution patterns of PNPs in the transwell system. These results indicate that PNPs display surface charge-specific interactions with ABC transporters and can even affect the bioavailability of toxic food-borne compounds (like pro-carcinogens).

Proceedings of the fourth annual participants' information meeting, DOE Low-Level Waste Management Program

Energy Technology Data Exchange (ETDEWEB)

Large, D.E.: Mezga, L.J.; Stratton, L.E.; Rose, R.R. (comps.)

1982-10-01

The Fourth Annual Participants' Information Meeting of the Department of Energy Low-Level Waste Management Program was held in Denver, Colorado, August 31 to September 2, 1982. The purpose of the meeting was to report and evaluate technology development funded by the program and to examine mechanisms for technology transfer. The meeting consisted of an introductory plenary session, followed by two concurrent overview sessions and then six concurrent technical sessions. There were two group meetings to review the findings of the technical sessions. The meeting concluded with a plenary summary session in which the major findings of the meeting were addressed. All papers have been abstracted and indexed for the Energy Data Base.

Novel understanding of ABC transporters ABCB1/MDR/P-glycoprotein, ABCC2/MRP2, and ABCG2/BCRP in colorectal pathophysiology

DEFF Research Database (Denmark)

Andersen, Vibeke; Svenningsen, Katrine; Almind Knudsen, Lina

2015-01-01

AIM: To evaluate ATP-binding cassette (ABC) transporters in colonic pathophysiology as they had recently been related to colorectal cancer (CRC) development. METHODS: Literature search was conducted on PubMed using combinations of the following terms: ABC transporters, ATP binding cassette...... with glucocorticoids. The evidence for the involvement of ABCC2 and ABCG2 in colonic pathophysiology was weak. CONCLUSION: ABCB1, diet, and gut microbes mutually interact in colonic inflammation, a well-known risk factor for CRC. Further insight may be translated into preventive and treatment strategies....... transporter proteins, inflammatory bowel disease, ulcerative, colitis, Crohns disease, colorectal cancer, colitis, intestinal inflammation, intestinal carcinogenesis, ABCB1/P-glycoprotein (P-gp/CD243/MDR1), ABCC2/multidrug resistance protein 2 (MRP2) and ABCG2/breast cancer resistance protein (BCRP), Abcb1...

Sustaining an Effective ABC-ABM System

Directory of Open Access Journals (Sweden)

Gary COKINS

2011-02-01

Full Text Available The purpose of this paper is to describe the Activity- Based Costing (ABC and Activity-Based Management (ABM system and techniques to sustain them as a permanent and repeatable production reporting system, not just for one-off analysis. A comparison is made between ABC/ABM modeling software that extracts source data and business systems that include ABC/ABM modeling features. There are presented the stages of updating, running and rerunning the ABC/ABM system. The resulting information calculated and provided by the ABC/ABM system are analyzed and interpreted in terms of a multidimensional data analysis. The article ends with the authors' conclusions about the benefits of continued operation of sustaining the ABC/ABM system.

ABC at Insteel Industries

OpenAIRE

V.G. Narayanan; Ratna G. Sarkar

1999-01-01

In this paper, we seek to provide empirical documentation of the effect of Activity-Based Costing (ABC) information on product and customer-related decisions made by managers in a company. Proponents of ABC argue that when an entity implements ABC, it reaps at least two important benefits: process improvements that promote more efficient use of resources and hence reduce costs, and a set of overhead cost numbers that, relative to traditional volume-based methods of costing, better represent t...

Meeting of the Technical Working Group on Fast Reactors (TWG-FR) (39th annual meeting). Working material

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-07-01

The 39th Annual Meeting of the Technical Working Group on Fast Reactors (TWG FR) was held from 15-19 May 2006 in Beijing, China, at the invitation of the China Institute of Atomic Energy (CIAEA). The meeting was attended by TWG-FR Members and Advisers from the following Member States (MS): Belgium (observer), Brazil, China, France, Germany, India, Italy, Japan, the Republic of Kazakhstan, the Republic of Korea, the Russian Federation, Sweden (observer), the United Kingdom, and the United States. Belarus, Switzerland, the European Commission, and OECD/NEA were unable to participate. Moreover, Prof. Carlo Rubbia, CERN director general emeritus, participated, upon IAEA invitation, in the meeting as distinguished scientist and IAEA expert. Mr. S.C. Chetal, from India (Indira Gandhi Centre for Atomic Research, IGCAR), was appointed chairman. The objectives of the meeting were to: - Exchange information on the national programmes on Fast Reactors (FR) and Accelerator Driven Systems (ADS); - Review the progress since the 38th TWG-FR Annual Meeting, including the status of the actions; - Consider meeting arrangements for 2006 and 2007; - Reviewed the Agency's ongoing information exchange and co-ordinated research activities in the technical fields relevant to the TWG-FR (FRs and ADS), as well as co-ordination of the TWG-FR's activities with other organizations; - Discuss future joint activities in view of the Agency's Programme and Budget Cycle 2008-2009 (and beyond)

Report on the 95th annual meeting of MSNS

Energy Technology Data Exchange (ETDEWEB)

1982-09-01

Coal recovery from coal wastes, acid rain, marketing and shipping Cape Breton coal, and coal blending are discussed briefly in this account of the activities and technical sessions of the Mining Society of Nova Scotia annual meeting that was held at Ingonish Beach, June 23-26, 1982.

2007 annual meeting on nuclear technology. Report

International Nuclear Information System (INIS)

Anon.

2007-01-01

This year's Annual Nuclear Technology Conference (JK) organized by the Deutsches Atomforum e.V. (DAtF) and the Kerntechnische Gesellschaft e.V. (KTG) was held in Karlsruhe on May 22-24. The attendance of more than 1,200 persons from 21 nations, and the increase in participation over the past few years, underline the role of this specialized congress as one of the leading international events in the field of the peaceful uses of nuclear power. The first day of the conference, with its plenary presentations, traditionally focused mainly on political and economic problems of the use of nuclear power. The situation of nuclear power in the United Kingdom, the key country of this year's meeting, was covered in depth. As usual, the program of the three-day event was organized as follows: plenary sessions on the first day were followed by topical sessions, technical sessions, and special events on the other days. This year, the conference featured a record program of 251 papers presented at these sessions. The 'Nuclear Power Campus' was arranged very successfully for the 5th time as an event comprising lectures and a 'hands-on' exhibition explaining the world of nuclear power in a transparent way to students from schools and universities. The special commitment to young scientists and to the preservation of competence in the nuclear field were emphasized at the JK 2007, among other things, in a workshop on 'Preservation of Competence in Nuclear Technology'. Nearly 20 young scientists presented results of their scientific work. The Annual Meeting on Nuclear Technology was accompanied by a specialized exhibition with meeting points of industry organized by 33 manufacturers, vendors, and service companies. (orig.)

Mouse ATP-Binding Cassette (ABC) Transporters Conferring Multi-Drug Resistance

Science.gov (United States)

Shuaizhang, L I; Zhang, Wen; Yin, Xuejiao; Xing, Shilai; Xie, Qunhui; Cao, Zhengyu; Zhao, Bin

2015-04-28

The ABC (ATP-binding cassette) transporter is one of the largest and most ancient protein families with members functioning from protozoa to human. The resistance of cancer and tumor cells to anticancer drugs is due to the over-expression of some ABC transporters, which may finally lead to chemotherapy failure. The mouse ABC transporters are classified into seven subfamilies by phylogenetic analysis. The mouse ABC transporter gene, alias, chromosomal location and function have been determined. Within the ABC super-family, the MDR transporters (Abcb1, Abcc1, Abcg2) in mouse models have been proved to be valuable to investigate the biochemistry and physiological functions. This review concentrates on the multidrug resistance of mouse ABC transporters in cancer and tumor cells.

The Australasian Society for Infectious Diseases Annual Scientific Meeting 2010.

Science.gov (United States)

Senanayake, Sanjaya N; Daveson, Kathryn L

2010-10-01

The 2010 Australasian Society for Infectious Diseases Annual Scientific Meeting took place in May in the Northern Territory (Australia) and focussed on infections in the region. The meeting highlights included the changing spectrum of malaria and dengue in endemic regions, the latest on influenza epidemiology, multidrug-resistant organisms and infectious diseases in the Australian indigenous population. This was complemented by subspeciality interest group research encompassing mycobacterial disease, infection control, mycology and virology.

25th Annual Meeting of ESNA/IUR: Soil-Plant Relationships

International Nuclear Information System (INIS)

Gerzabek, M. H.

1995-12-01

The radioecological session of the 25 th annual meeting of ESNA (Piacenza/Italy) and some other proceedings are of interest for INIS. The main content of these proceedings is the soil-to-plant transfer of radioisotopes. (Botek)

26{sup th} Annual ESNA/IUR Meeting: Soil-Plant Relationships

Energy Technology Data Exchange (ETDEWEB)

Gerzabek, M H [ed.; Oesterreichisches Forschungszentrum Seibersdorf, 2444 Seibersdorf (Austria)

1996-11-01

The radioecological session of the 26{sup th} annual meeting of ESNA (in Busteni/Romania) is for INIS interesting. The session was a joint session with the soil-to-plant transfer working group of the IUR. (Botek)

2013 NIEHS/EPA Children's Centers Annual Meeting: Protecting Children's Health for a Lifetime

Science.gov (United States)

This report includes proceedings from the 2013 NIEHS/EPA Children's Centers Annual Meeting, held in Washington D.C. in October, 2013. Summaries of presentations, speaker biosketches, poster abstracts, and a meeting participant list are all included.

American Telemedicine Association: 18th Annual International Meeting & Tradeshow

Directory of Open Access Journals (Sweden)

Benjamin Forstag

2012-12-01

Full Text Available For 18 years, the American Telemedicine Association (ATA Annual International Meeting & Exposition has been the premier forum for professionals in the telemedicine, telehealth and mHealth space -- one of the fastest growing meetings in the country. ATA 2013 is on course to be the largest ATA meeting ever, with over 6,000 projected attendees.  The program will include 500 educational sessions and posters, highlighting the latest innovations, applications and research in telemedicine. The 2013 exhibit hall will feature nearly 300 of the leading vendors in remote healthcare technologies. With over 6000 projected attendees, from all around the world, there's no better place to meet and network with your peers and thought leaders in the field. Detailed program information--including courses, sessions and CME information--will be available January 2013 at:http://www.americantelemed.org.

2015 Annual Meeting of the German Gesellschaft für Arbeitswissenschaft

CERN Document Server

Stock, Patricia; Bruder, Ralph; Schlick, Christopher

2016-01-01

These proceedings summarize the best papers in each research area represented at the 2015 Annual Meeting of the German Gesellschaft für Arbeitswissenschaft, held at Karlsruhe Institute of Technology (KIT) from February 26-28. The meeting featured more than 160 presentations and 30 posters reflecting the diversity of subject matter in the field of human and industrial engineering.

Proceedings of the KSME 2009 fall annual meeting

Energy Technology Data Exchange (ETDEWEB)

NONE

2009-07-01

This proceedings contains articles of the KSME 2009 fall annual meeting. It was held on 4-6 Nov, 2009 in Pyeongchang, Korea. This proceedings is comprised of 10 sessions. The main subject titles of session are as follows: materials and fracture mechanics, CAE and applied mechanics, dynamics and control, fabrication and design, reliability, biotechnology, micro/nano-mechanics, thermodynamics, fluid mechanics, energy and dynamics. (Yi, J. H.)

Phylogenetic analysis of fungal ABC transporters.

Science.gov (United States)

Kovalchuk, Andriy; Driessen, Arnold J M

2010-03-16

The superfamily of ABC proteins is among the largest known in nature. Its members are mainly, but not exclusively, involved in the transport of a broad range of substrates across biological membranes. Many contribute to multidrug resistance in microbial pathogens and cancer cells. The diversity of ABC proteins in fungi is comparable with those in multicellular animals, but so far fungal ABC proteins have barely been studied. We performed a phylogenetic analysis of the ABC proteins extracted from the genomes of 27 fungal species from 18 orders representing 5 fungal phyla thereby covering the most important groups. Our analysis demonstrated that some of the subfamilies of ABC proteins remained highly conserved in fungi, while others have undergone a remarkable group-specific diversification. Members of the various fungal phyla also differed significantly in the number of ABC proteins found in their genomes, which is especially reduced in the yeast S. cerevisiae and S. pombe. Data obtained during our analysis should contribute to a better understanding of the diversity of the fungal ABC proteins and provide important clues about their possible biological functions.

24{sup th} Annual ESNA/IUR Meeting: Soil-Plant Relationships

Energy Technology Data Exchange (ETDEWEB)

Gerzabek, M H [ed.; Oesterreichisches Forschungszentrum Seibersdorf, 2444 Seibersdorf (Austria)

1994-11-01

The 24{sup th} annual meeting of ESNA was jointly organized with the IUR (International Union of Radioecologists), working group soil-to-plant transfer in Varna, Bulgaria. For INIS interesting is the session 'behaviour of radionuclides in the terrestrial foodchain'. (Botek)

81st Annual Meeting of the Psychometric Society

CERN Document Server

Wiberg, Marie; Culpepper, Steven; Douglas, Jeffrey; Wang, Wen-Chung

2017-01-01

This proceedings volume compiles and expands on selected and peer reviewed presentations given at the 81st Annual Meeting of the Psychometric Society (IMPS), organized by the University of North Carolina at Greensboro, and held in Asheville, North Carolina, July 11th to 17th, 2016. IMPS is one of the largest international meetings focusing on quantitative measurement in psychology, education, and the social sciences, both in terms of participants and number of presentations. The meeting built on the Psychometric Society's mission to share quantitative methods relevant to psychology, addressing a diverse set of psychometric topics including item response theory, factor analysis, structural equation modeling, time series analysis, mediation analysis, cognitive diagnostic models, and multi-level models. Selected presenters were invited to revise and expand their contributions and to have them peer reviewed and published in this proceedings volume. Previous volumes to showcase work from the Psychometric Society�...

Eleventh annual meeting, Bologna, Italy, 17-20 April 1978. Summary report. Part I

Energy Technology Data Exchange (ETDEWEB)

NONE

1978-06-01

The Summary Report of the Eleventh Annual Meeting of the IAEA International Working Group on Fast Reactors contains the Minutes of the Meeting (Part I); the papers which review the national programmes in the field of LMFBRs and other presentations at the Meeting (Part II); and the discussions on the review of the national programmes (Part III)

Technical meeting (TM) to 'Review of national programmes on fast reactors and accelerator driven systems (ADS)'. Technical Working Group on Fast Reactors (TWG-FR) (37th annual meeting). Working material

Energy Technology Data Exchange (ETDEWEB)

NONE

2004-07-01

The objectives of the 37th Annual Meeting of the Technical Working Group on Fast Reactors, were to: 1) exchange information on the national programmes on Fast Reactors (FR) and Accelerator Driven Systems (ADS); 2) review the progress since the 36th TWG-FR Annual Meeting, including the status of the actions; 3) consider meeting arrangements for 2004 and 2005; 4) review the Agency's co-ordinated research activities in the field of FRs and ADS, as well as co-ordination of the TWG-FR's activities with other organizations. The participants made presentations on the status of the respective national programmes on FR and ADS development. A summary of the highlights for the period since the 36th TWG-FR Annual Meeting is included in this proceedings. Annex IV contains the Review of National Programs on Fast Reactors and Accelerator Driven Systems (ADS), and the TWG-FR Activity Report for the Period May 2003-April 2004.

Progress report on nuclear science and technology in China (Vol.2). Proceedings of academic annual meeting of China Nuclear Society in 2011, No.2--nuclear power sub-volume (Pt.1)

International Nuclear Information System (INIS)

2012-10-01

Progress report on nuclear science and technology in China (Vol. 2) includes 698 articles which are communicated on the second national academic annual meeting of China Nuclear Society. There are 10 books totally. This is the second one, the content is about nuclear power (Pt.1)

13th annual meeting of the ALS Users' Association

International Nuclear Information System (INIS)

Robinson, Art

2000-01-01

A complement of 266 users, staff, and vendors descended upon the Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) from Monday through Wednesday, October 16-18, 2000 for the thirteenth edition of the annual Advanced Light Source (ALS) users meeting. In a departure from previous practice, the meeting featured an increased emphasis on workshops with the result that the proceedings were equally divided between oral and poster presentations and the workshops. After the traditional welcomes and facility updates on the first morning, science dominated the first day and a half comprising the formal meeting with a session of highlights from young researchers, three sessions of scientific highlights from the ALS and elsewhere, and a poster session that included a student poster competition. A set of seven workshops covering research areas of current or growing interest at the ALS rounded out the final day and a half of the meeting

[The 10th Annual Meeting of the Japanese Society for Pharmaceutical Palliative Care and Sciences].

Science.gov (United States)

Shiokawa, Mitsuru; Kawamura, Kazumi

2018-01-01

　The 10th Annual Meeting of the Japanese Society for Pharmaceutical Palliative Care and Sciences was held at Act City Hamamatsu, Japan, with a total of 2634 participants in attendance. The theme of the meeting was realized through a number of new concepts, such as a debate symposium, information sessions, nurses' workshops, and so on. The results obtained from the participation questionnaire (n=438), which were aggregated up to 1 month following the end of this year's meeting, revealed that 89% of the participants at considered it to have been appealing. In particular, 63% of the participants favored the adoption of a debate symposium whereby it was possible to ask and respond to questions in real time. In the free comments section of the questionnaire, the participants expressed how they felt the debate symposium made it easy to give their opinions, and that this element might be further developed in the future. They also stated that they found the introduction of the Clica system effective in terms of making the annual meeting an active learning place. One issue that was highlighted concerned the observation that the hall used to host the symposium was designed as a concert venue, which meant it was highly shielded from the outside environment, in addition to access to the internet being blocked. I hope that many of the projects from this Annual Meeting will serve to guide the future style of the Society's Annual Meetings.

[Participants-centered Design of Annual Meeting: From the Perspectives of Instructional Systems].

Science.gov (United States)

Suzuki, Katsuaki

2018-01-01

　This paper examines the reform experience of the 10th Annual Meeting of the Japanese Society for Pharmaceutical Palliative Care and Sciences from Instructional Systems perspectives, to check whether it was effective, efficient, and appealing for participants. "Instructional Systems" has been a research area in educational technology for the past 50 years, and has also been applied to training and human resource development in healthcare domains. If an annual meeting is to be designed for participants' learning, then perspectives of Instructional Systems can be applied to interpret the effort of the reform. First, fill in the gaps of participants' knowledge, using before-and-after comparison. Design a conference to meet the needs of its participants by checking why they attend (expectations) and what they bring in (starting status). Second, design the conference as a process of innovation. The bigger the expected changes, the more carefully participants should be prepared to accommodate them. Third, follow plan-do-check-action cycles with data for confirming and revising the new ways of running the meeting. Plan to check "exportability" of the new ways, to assess whether it can be generalized to future meetings.

Sustaining an Effective ABC-ABM System

OpenAIRE

Gary COKINS; Sorinel CĂPUŞNEANU

2011-01-01

The purpose of this paper is to describe the Activity- Based Costing (ABC) and Activity-Based Management (ABM) system and techniques to sustain them as a permanent and repeatable production reporting system, not just for one-off analysis. A comparison is made between ABC/ABM modeling software that extracts source data and business systems that include ABC/ABM modeling features. There are presented the stages of updating, running and rerunning the ABC/ABM system. The resul...

77th Annual Meeting | Annual Meetings | Events | Indian Academy of ...

Indian Academy of Sciences (India)

Open source drug discovery: A model for science 2.0 through crowd sourcing. 09.40-10.20 ... Symposium on (a) Recent Trends in High Energy Physics: 10.50. SUNANDA ... Business Meeting of Fellows (Seminar Hall). 17.30. Tea Break.

Frequent down-regulation of ABC transporter genes in prostate cancer.

Science.gov (United States)

Demidenko, Rita; Razanauskas, Deividas; Daniunaite, Kristina; Lazutka, Juozas Rimantas; Jankevicius, Feliksas; Jarmalaite, Sonata

2015-10-12

ATP-binding cassette (ABC) transporters are transmembrane proteins responsible for the efflux of a wide variety of substrates, including steroid metabolites, through the cellular membranes. For better characterization of the role of ABC transporters in prostate cancer (PCa) development, the profile of ABC transporter gene expression was analyzed in PCa and noncancerous prostate tissues (NPT). TaqMan Low Density Array (TLDA) human ABC transporter plates were used for the gene expression profiling in 10 PCa and 6 NPT specimens. ABCB1 transcript level was evaluated in a larger set of PCa cases (N = 78) and NPT (N = 15) by real-time PCR, the same PCa cases were assessed for the gene promoter hypermethylation by methylation-specific PCR. Expression of eight ABC transporter genes (ABCA8, ABCB1, ABCC6, ABCC9, ABCC10, ABCD2, ABCG2, and ABCG4) was significantly down-regulated in PCa as compared to NPT, and only two genes (ABCC4 and ABCG1) were up-regulated. Down-regulation of ABC transporter genes was prevalent in the TMPRSS2-ERG-negative cases. A detailed analysis of ABCB1 expression confirmed TLDA results: a reduced level of the transcript was identified in PCa in comparison to NPT (p = 0.048). Moreover, the TMPRSS2-ERG-negative PCa cases showed significantly lower expression of ABCB1 in comparison to NPT (p = 0.003) or the fusion-positive tumors (p = 0.002). Promoter methylation of ABCB1 predominantly occurred in PCa and was rarely detected in NPT (p ABC transporter genes in PCa, especially in the TMPRSS2-ERG-negative tumors.

The ABC and AUSSAT.

Science.gov (United States)

McGarritty, Ian

1985-01-01

Discusses the Australian Broadcasting Corporation's (ABC) utilization of the AUSSAT telecommunications satellite to extend its television and radio transmission range to reach remote Australian audiences; the satellite's program gathering and interchange capabilities; and ABC's generation of other benefits to offset cost of satellite services.…

University Research Consortium annual review meeting program

International Nuclear Information System (INIS)

1996-07-01

This brochure presents the program for the first annual review meeting of the University Research Consortium (URC) of the Idaho National Engineering Laboratory (INEL). INEL is a multiprogram laboratory with a distinctive role in applied engineering. It also conducts basic science research and development, and complex facility operations. The URC program consists of a portfolio of research projects funded by INEL and conducted at universities in the United States. In this program, summaries and participant lists for each project are presented as received from the principal investigators

University Research Consortium annual review meeting program

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-07-01

This brochure presents the program for the first annual review meeting of the University Research Consortium (URC) of the Idaho National Engineering Laboratory (INEL). INEL is a multiprogram laboratory with a distinctive role in applied engineering. It also conducts basic science research and development, and complex facility operations. The URC program consists of a portfolio of research projects funded by INEL and conducted at universities in the United States. In this program, summaries and participant lists for each project are presented as received from the principal investigators.

24 Annual meeting of the Spanish Nuclear Society, Valladolid 14-16 October 1998

International Nuclear Information System (INIS)

1998-01-01

The technical sessions of XXIV annual meeting of the Spanish Nuclear Society were: 1) Fusion 2) Engineering: calculation and simulation. 3) Economical, legal and social aspect. 4) Plant life extension 5) Operating experiences, refueling and operation support 6) Probabilistic safety 7) Radiological protection 8) Waste management 9)Maintenance 10) Nuclear Safety R and D. 11)Environmental aspects 12) Fuel 13) Quality

Minutes of the Fourth Annual Meeting of the Panel on Reference Nuclear Data, Brookhaven National Laboratory, November 1-2, 1979

International Nuclear Information System (INIS)

Burrows, T.W.; Stewart, L.; Coyne, J.J.

1980-06-01

After the welcome and approval of the agenda and of the minutes of the Third Annual Meeting, the participants turned to reactor physics data needs, CTR data needs, status of international and national cooperation, status and availability of data files, election of officers, status of publications, biomedical data needs, and miscellaneous action items from the Third Meeting. A summary of recommendations and action items is given. Eighteen appendixes are included

ABCE1 is a highly conserved RNA silencing suppressor.

Directory of Open Access Journals (Sweden)

Kairi Kärblane

Full Text Available ATP-binding cassette sub-family E member 1 (ABCE1 is a highly conserved protein among eukaryotes and archaea. Recent studies have identified ABCE1 as a ribosome-recycling factor important for translation termination in mammalian cells, yeast and also archaea. Here we report another conserved function of ABCE1. We have previously described AtRLI2, the homolog of ABCE1 in the plant Arabidopsis thaliana, as an endogenous suppressor of RNA silencing. In this study we show that this function is conserved: human ABCE1 is able to suppress RNA silencing in Nicotiana benthamiana plants, in mammalian HEK293 cells and in the worm Caenorhabditis elegans. Using co-immunoprecipitation and mass spectrometry, we found a number of potential ABCE1-interacting proteins that might support its function as an endogenous suppressor of RNA interference. The interactor candidates are associated with epigenetic regulation, transcription, RNA processing and mRNA surveillance. In addition, one of the identified proteins is translin, which together with its binding partner TRAX supports RNA interference.

28. Annual Meeting of the European Environmental Mutagen Society

International Nuclear Information System (INIS)

1998-09-01

The 28 th Annual Meeting of the European Environmental Mutagen Society took place in Salzburg from September 7 th till September 11 th , 1998. A lot of presentations also dealt with many radiation effects on cells, chromosomal aberrations and genetic effects caused by radioactive irradiation. In vivo and in vitro experiments concerning radiation injuries and carcinomas are analyzed. (Cecil)

Meeting of the Technical Working Group on Fast Reactors (TWG-FR) (41st Annual Meeting). Working Material

International Nuclear Information System (INIS)

2008-01-01

The objectives of the meeting were to: - Exchange information on the national programmes on Fast Reactors (FR) and Accelerator Driven Systems (ADS); - Review the progress since the 40th TWG-FR Annual Meeting, including the status of the actions; - Consider meeting arrangements for 2008, 2009, 2010 and beyond; - Review the IAEA’s ongoing information exchange and coordinated research activities in the technical fields relevant to the TWG-FR (FRs and ADS), as well as coordination of the TWG-FR’s activities with other organizations and international initiatives; - Discuss future joint activities in view of IAEA’s Programme and Budget Cycles beyond 2008-2009

Novel agents and regimens for acute myeloid leukemia: 2009 ASH annual meeting highlights

Directory of Open Access Journals (Sweden)

Zhu Xiongpeng

2010-04-01

Full Text Available Abstract Prognostic markers, such as NPM1, Flt3-ITD, and cytogenetic abnormalities have made it possible to formulate aggressive treatment plans for unfavorable acute myeloid leukemia (AML. However, the long-term survival of AML with unfavorable factors remains unsatisfactory. The latest data indicate that the standard dose of daunorubicin (DNR at 45 mg/m2 is inferior to high dose 90 mg/m2 for induction therapy. The rates of complete remission and overall survival are significantly better in the high dose induction regimen. New regimens exploring the new liposomal encapsulation of Ara-C and DNR as well as addition of gemtuzumab ozogamicin monoclonal antibody have been studied. New agents, including the nucleoside analogues (clofarabine, sapacitabine, elacytarabine, FLT3 inhibitor (sorafenib, farnesyl-transferase inhibitor (tipifarnib, histone deacetylase inhibitor (vorinostat, lenalidomide, as well as DNA methyltransferase inhibitors (decitabine, azacitidine, were recently reported for AML treatment in the 2009 ASH annual meeting. This review also summarizes the updates of the clinical trials on novel agents including voreloxin, AS1413, behenoylara-C, ARRY520, ribavirin, AZD1152, AZD6244, and terameprocol (EM-1421 from the 2009 ASH annual meeting.

Frequent down-regulation of ABC transporter genes in prostate cancer

International Nuclear Information System (INIS)

Demidenko, Rita; Razanauskas, Deividas; Daniunaite, Kristina; Lazutka, Juozas Rimantas; Jankevicius, Feliksas; Jarmalaite, Sonata

2015-01-01

ATP-binding cassette (ABC) transporters are transmembrane proteins responsible for the efflux of a wide variety of substrates, including steroid metabolites, through the cellular membranes. For better characterization of the role of ABC transporters in prostate cancer (PCa) development, the profile of ABC transporter gene expression was analyzed in PCa and noncancerous prostate tissues (NPT). TaqMan Low Density Array (TLDA) human ABC transporter plates were used for the gene expression profiling in 10 PCa and 6 NPT specimens. ABCB1 transcript level was evaluated in a larger set of PCa cases (N = 78) and NPT (N = 15) by real-time PCR, the same PCa cases were assessed for the gene promoter hypermethylation by methylation-specific PCR. Expression of eight ABC transporter genes (ABCA8, ABCB1, ABCC6, ABCC9, ABCC10, ABCD2, ABCG2, and ABCG4) was significantly down-regulated in PCa as compared to NPT, and only two genes (ABCC4 and ABCG1) were up-regulated. Down-regulation of ABC transporter genes was prevalent in the TMPRSS2-ERG-negative cases. A detailed analysis of ABCB1 expression confirmed TLDA results: a reduced level of the transcript was identified in PCa in comparison to NPT (p = 0.048). Moreover, the TMPRSS2-ERG-negative PCa cases showed significantly lower expression of ABCB1 in comparison to NPT (p = 0.003) or the fusion-positive tumors (p = 0.002). Promoter methylation of ABCB1 predominantly occurred in PCa and was rarely detected in NPT (p < 0.001). The study suggests frequent down-regulation of the ABC transporter genes in PCa, especially in the TMPRSS2-ERG-negative tumors. The online version of this article (doi:10.1186/s12885-015-1689-8) contains supplementary material, which is available to authorized users

The role of the atypical kinases ABC1K7 and ABC1K8 in abscisic acid responses

Directory of Open Access Journals (Sweden)

Anna eManara

2016-03-01

Full Text Available The ABC1K family of atypical kinases (activity of bc1 complex kinase is represented in bacteria, archaea and eukaryotes. In plants they regulate diverse physiological processes in the chloroplasts and mitochondria, but their precise functions are poorly defined. ABC1K7 and ABC1K8 are probably involved in oxidative stress responses, isoprenyl lipid synthesis and distribution of iron within chloroplasts. Because reactive oxygen species take part in abscisic acid (ABA-mediated processes, we investigated the functions of ABC1K7 and ABC1K8 during germination, stomatal movement and leaf senescence. Both genes were upregulated by ABA treatment and some ABA-responsive physiological processes were affected in abc1k7 and abc1k8 mutants. Germination was more severely affected by ABA, osmotic stress and salt stress in the single and double mutants; the stomatal aperture was smaller in the mutants under standard growth conditions and was not further reduced by exogenous ABA application; ABA-induced senescence symptoms were more severe in the leaves of the single and double mutants compared to wild type leaves. Taken together, our results suggest that ABC1K7 and ABC1K8 might be involved in the cross-talk between ABA and ROS signaling.

The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane

DEFF Research Database (Denmark)

Rocchi, E; Khodjakov, A; Volk, E L

2000-01-01

by Western blot and immunohistochemistry. This protein is highly overexpressed in several drug-resistant cell lines and localizes predominantly to the plasma membrane, instead of to intracellular membranes as seen with all other known half-transporters. Therefore, BCRP/MXR is unique among the ABC half......The products of the ABC gene family can be generally classified as either full-transporters of half-transporters. Full-transporters are expressed in the plasma membrane, whereas half-transporters are usually found in intracellular membranes. Recently, an ABC half-transporter, the ABCG2 gene product......-transporters by being localized to the plasma membrane....

Minutes of the Fourth Annual Meeting of the Panel on Reference Nuclear Data, Brookhaven National Laboratory, November 1-2, 1979. [BNL, Nov. 1-2, 1979

Energy Technology Data Exchange (ETDEWEB)

Burrows, T.W.; Stewart, L.; Coyne, J.J. (eds.)

1980-06-01

After the welcome and approval of the agenda and of the minutes of the Third Annual Meeting, the participants turned to reactor physics data needs, CTR data needs, status of international and national cooperation, status and availability of data files, election of officers, status of publications, biomedical data needs, and miscellaneous action items from the Third Meeting. A summary of recommendations and action items is given. Eighteen appendixes are included. (RWR)

28. Annual Meeting of the European Environmental Mutagen Society

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-09-01

The 28{sup th} Annual Meeting of the European Environmental Mutagen Society took place in Salzburg from September 7{sup th} till September 11{sup th}, 1998. A lot of presentations also dealt with many radiation effects on cells, chromosomal aberrations and genetic effects caused by radioactive irradiation. In vivo and in vitro experiments concerning radiation injuries and carcinomas are analyzed. (Cecil)

26th annual meeting of the Japanese Neuroradiological Society. Abstracts

International Nuclear Information System (INIS)

Anon.

1997-01-01

The annual meeting of neuroradiology in Tokyo gives a good overview of the present topics in radiology. Emphasis is placed on NMR imaging of the brain, the skeleton and the cardiovascular system according to the occurrence of diseases like neoplasms, pathological changes and malformations in these organs. (AJ)

The 23rd Annual Meeting of the European Tissue Repair Society (ETRS) in Reims, France

DEFF Research Database (Denmark)

Von den Hoff, Johannes W; Ågren, Sven Per Magnus; Coulomb, Bernard

2014-01-01

The 23rd Annual Meeting of the European Tissue Repair Society, Reims, France, October 23 to 25, 2013 focused on tissue repair and regenerative medicine covering topics such as stem cells, biomaterials, tissue engineering, and burns.......The 23rd Annual Meeting of the European Tissue Repair Society, Reims, France, October 23 to 25, 2013 focused on tissue repair and regenerative medicine covering topics such as stem cells, biomaterials, tissue engineering, and burns....

78 FR 6811 - North Pacific Fishery Management Council; Public Meeting

Science.gov (United States)

2013-01-31

... status of scallop stocks, recommend annual ABC level for statewide stock, compile annual SAFE report, receive report on potential impacts of ocean acidification on scallops, review stock structure for weathervane scallops and recommend annual research priorities. The Agenda is subject to change, and the latest...

25{sup th} Annual Meeting of ESNA/IUR: Soil-Plant Relationships

Energy Technology Data Exchange (ETDEWEB)

Gerzabek, M H [ed.; Oesterreichisches Forschungszentrum Seibersdorf, 2444 Seibersdorf (Austria)

1995-12-01

The radioecological session of the 25{sup th} annual meeting of ESNA (Piacenza/Italy) and some other proceedings are of interest for INIS. The main content of these proceedings is the soil-to-plant transfer of radioisotopes. (Botek)

Proceedings of the seventh annual gasification and gas stream cleanup systems contractors review meeting: Volume 2

Energy Technology Data Exchange (ETDEWEB)

Ghate, M.R.; Markel, K.E. Jr.; Jarr, L.A.; Bossart, S.J. (eds.)

1987-08-01

On June 16 through 19, 1987, METC sponsored the Seventh Annual Gasification and Gas Stream Cleanup Systems Contractors Review Meeting which was held at the Sheraton Lakeview Conference Center in Morgantown, West Virginia. The primary purpose of the meeting was threefold: to review the technical progress and current status of the gasification and gas stream cleanup projects sponsored by the Department of Energy; to foster technology exchange among participating researchers and other technical communities; to facilitate interactive dialogues which would identify research needs that would make coal-based gasification systems more attractive economically and environmentally. More than 310 representatives of Government, academia, industry, and foreign energy research organizations attended the 4-day meeting. Fifty-three papers and thirty poster dsplays were presented summarizing recent developments in the gasification and gas stream cleanup programs. Volume II covers papers presented at sessions 5 and 6 on system for the production of synthesis gas, and on system for the production of power. All papers have been processed for inclusion in the Energy Data Base.

Tenth annual meeting, Vienna, Austria, 29 March - 1 April 1977. Summary report. Part I

Energy Technology Data Exchange (ETDEWEB)

NONE

1977-05-01

The Summary Report of Tenth Annual Meeting of the IAEA International Working Group on Fast Reactors contains the Minutes of the Meeting (Part I); the papers which review the national programmes in the field of LMFBRs and other presentations at the Meeting (Part II); and the discussions on the review of the national programmes (Part III)

Diversity and evolution of ABC proteins in basidiomycetes.

Science.gov (United States)

Kovalchuk, Andriy; Lee, Yong-Hwan; Asiegbu, Fred O

2013-01-01

ABC proteins constitute one of the largest families of proteins. They are implicated in wide variety of cellular processes ranging from ribosome biogenesis to multidrug resistance. With the advance of fungal genomics, the number of known fungal ABC proteins increases rapidly but the information on their biological functions remains scarce. In this work we extended the previous analysis of fungal ABC proteins to include recently sequenced species of basidiomycetes. We performed an identification and initial cataloging of ABC proteins from 23 fungal species representing 10 orders within class Agaricomycotina. We identified more than 1000 genes coding for ABC proteins. Comparison of sets of ABC proteins present in basidiomycetes and ascomycetes revealed the existence of two groups of ABC proteins specific for basidiomycetes. Results of survey should contribute to the better understanding of evolution of ABC proteins in fungi and support further experimental work on their characterization.

77 FR 19646 - International Whaling Commission; 64th Annual Meeting; Nominations

Science.gov (United States)

2012-04-02

... Commissioner representing the positions of non-governmental organizations. Generally, only one non-governmental... the U.S. IWC Commissioner representing the positions of non-governmental organizations. Generally... International Whaling Commission; 64th Annual Meeting; Nominations AGENCY: National Marine Fisheries Service...

77 FR 52784 - U.S. Department of State Advisory Committee on Private International Law: Notice of Annual Meeting

Science.gov (United States)

2012-08-30

... Choice of Court Agreements; international contract law; developments in major PIL organizations... International Law: Notice of Annual Meeting The Department of State's Advisory Committee on Private International Law (ACPIL) will hold its annual meeting on developments in private international law on Thursday...

How senior entomologists can be involved in the annual meeting: organization and the coming together of a large event

Science.gov (United States)

The Annual Meeting for the Entomological Society of America is a large event where planning is started at the end of the previous years’ meeting. The President of the Society named the Program Committee Co-Chairs for Entomology 2017 at the 2015 Annual Meeting, so that they could handle the duties o...

Bioinformatic survey of ABC transporters in dermatophytes.

Science.gov (United States)

Gadzalski, Marek; Ciesielska, Anita; Stączek, Paweł

2016-01-15

ATP binding cassette (ABC) transporters constitute a very large and ubiquitous superfamily of membrane proteins. They are responsible for ATP hydrolysis driven translocation of countless substrates. Being a very old and diverse group of proteins present in all organisms they share a common feature, which is the presence of an evolutionary conservative nucleotide binding domain (NBD)--the engine that drives the transport. Another common domain is a transmembrane domain (TMD) which consists of several membrane-spanning helices. This part of protein is substrate-specific, thus it is much more variable. ABC transporters are known for driving drug efflux in many pathogens and cancer cells, therefore they are the subject of extensive studies. There are many examples of conferring a drug resistance phenotype in fungal pathogens by ABC transporters, however, little is known about these proteins in dermatophytes--a group of fungi causing superficial mycoses. So far only a single ABC transporter has been extensively studied in this group of pathogens. We analyzed available genomic sequences of seven dermatophyte species in order to provide an insight into dermatophyte ABC protein inventory. Phylogenetic studies of ABC transporter genes and their products were conducted and included ABC transporters of other fungi. Our results show that each dermatophyte genome studied possesses a great variety of ABC transporter genes. Detailed analysis of selected genes and their products indicates that relatively recent duplication of ABC transporter genes could lead to novel substrate specificity. Copyright © 2015 Elsevier B.V. All rights reserved.

76 FR 34209 - International Whaling Commission; 63rd Annual Meeting; Nominations

Science.gov (United States)

2011-06-13

... Commissioner representing the positions of non-governmental organizations. Generally, only one non-governmental... recommendations to the U.S. IWC Commissioner representing the positions of non-governmental organizations... International Whaling Commission; 63rd Annual Meeting; Nominations AGENCY: National Marine Fisheries Service...

The possibility of fuel cycle design for ABC/ATW complex with molten fuel on LiF-BeF2 basis

International Nuclear Information System (INIS)

Naumov, V.S.; Bychkov, A.V.

1995-01-01

The experience gained in the field of the development of molten salt reactors (MSR) can be made a basis of chemical processing of the ABC/ATW liquid fuel. The following combination of two processing principles are proposed for the ABC/ATW fuel (LiF-BeF 2 -PuF 3,(4) - MAF n ): - continious removal of radioactive gases, volatile impurities and 'noble fission products'; - portion-by-portion electrochemical processing with removal of rare earth elements and some other fission products at an autonomous plant. After processing the fuel salt is brought back to the blanket of the ABC/ATW complex. The analysis of information previously published in different countries allows for a safe assumption that the ABC/ATW fuel cycle with liquid fuel salt is feasible and can be demonstrated experimentally

The possibility of fuel cycle design for ABC/ATW complex with molten fuel on LiF-BeF2 basis

International Nuclear Information System (INIS)

Naumov, V. S.; Bychkov, A. V.

1995-01-01

The experience gained in the field of the development of molten salt reactors (MSR) can be made a basis of chemical processing of the ABC/ATW liquid fuel. The following combination of two processing principles are proposed for the ABC/ATW fuel (LiF-BeF2-PuF3,(4)-MAFn): -continious removal of radioactive gases, volatile impurities and 'noble fission products'; -portion-by-portion electrochemical processing with removal of rare earth elements and some other fission products at an autonomous plant. After processing the fuel salt is brought back to the blanket of the ABC/ATW complex. The analysis of information previously published in different countries allows for a safe assumption that the ABC/ATW fuel cycle with liquid fuel salt is feasible and can be demonstrated experimentally

23rd annual meeting of German Society for Neuroradiology

International Nuclear Information System (INIS)

Kuehne, D.

1987-01-01

Book of abstracts of this annual meeting summarizing the 58 lectures that dealt with the following subjects: Pathologic changes of the cervical vertebral canal and of the cervico-occipital region, as detected by modern imaging techniques (18 papers); diagnostic examination of the urbita and the middle cranial fossa (12 papers); invasive methods of neuroradiology (13 papers); 15 papers on freely chosen subjects. (MG) [de

IBC's 23rd Annual Antibody Engineering, 10th Annual Antibody Therapeutics international conferences and the 2012 Annual Meeting of The Antibody Society: December 3-6, 2012, San Diego, CA.

Science.gov (United States)

Klöhn, Peter-Christian; Wuellner, Ulrich; Zizlsperger, Nora; Zhou, Yu; Tavares, Daniel; Berger, Sven; Zettlitz, Kirstin A; Proetzel, Gabriele; Yong, May; Begent, Richard H J; Reichert, Janice M

2013-01-01

The 23rd Annual Antibody Engineering, 10th Annual Antibody Therapeutics international conferences, and the 2012 Annual Meeting of The Antibody Society, organized by IBC Life Sciences with contributions from The Antibody Society and two Scientific Advisory Boards, were held December 3-6, 2012 in San Diego, CA. The meeting drew over 800 participants who attended sessions on a wide variety of topics relevant to antibody research and development. As a prelude to the main events, a pre-conference workshop held on December 2, 2012 focused on intellectual property issues that impact antibody engineering. The Antibody Engineering Conference was composed of six sessions held December 3-5, 2012: (1) From Receptor Biology to Therapy; (2) Antibodies in a Complex Environment; (3) Antibody Targeted CNS Therapy: Beyond the Blood Brain Barrier; (4) Deep Sequencing in B Cell Biology and Antibody Libraries; (5) Systems Medicine in the Development of Antibody Therapies/Systematic Validation of Novel Antibody Targets; and (6) Antibody Activity and Animal Models. The Antibody Therapeutics conference comprised four sessions held December 4-5, 2012: (1) Clinical and Preclinical Updates of Antibody-Drug Conjugates; (2) Multifunctional Antibodies and Antibody Combinations: Clinical Focus; (3) Development Status of Immunomodulatory Therapeutic Antibodies; and (4) Modulating the Half-Life of Antibody Therapeutics. The Antibody Society's special session on applications for recording and sharing data based on GIATE was held on December 5, 2012, and the conferences concluded with two combined sessions on December 5-6, 2012: (1) Development Status of Early Stage Therapeutic Antibodies; and (2) Immunomodulatory Antibodies for Cancer Therapy.

Second-order nonlinear optical metamaterials: ABC-type nanolaminates

International Nuclear Information System (INIS)

Alloatti, L.; Kieninger, C.; Lauermann, M.; Köhnle, K.; Froelich, A.; Wegener, M.; Frenzel, T.; Freude, W.; Leuthold, J.; Koos, C.

2015-01-01

We demonstrate a concept for second-order nonlinear metamaterials that can be obtained from non-metallic centrosymmetric constituents with inherently low optical absorption. The concept is based on iterative atomic-layer deposition of three different materials, A = Al 2 O 3 , B = TiO 2 , and C = HfO 2 . The centrosymmetry of the resulting ABC stack is broken since the ABC and the inverted CBA sequences are not equivalent—a necessary condition for non-zero second-order nonlinearity. In our experiments, we find that the bulk second-order nonlinear susceptibility depends on the density of interfaces, leading to a nonlinear susceptibility of 0.26 pm/V at a wavelength of 800 nm. ABC-type nanolaminates can be deposited on virtually any substrate and offer a promising route towards engineering of second-order optical nonlinearities at both infrared and visible wavelengths

Immunotherapies in transplantation and cancer: 22nd NAT meeting/2nd NAT LabEx IGO joint meeting; 1-2 June 2017, Nantes, France.

Science.gov (United States)

Simon, Sylvain; Charpentier, Maud; Anegon, Ignacio; Labarriere, Nathalie

2017-09-01

This 22nd edition of the Nantes Actualités Transplantation annual meeting was co-organized for the second time with the LabEx Immuno-Graft Oncology network. This international meeting was held on 1 and 2 June 2017 in Nantes (western France). The topic of this 2-day meeting was 'Immunotherapies in transplantation and cancer'. This meeting brought together 17 international invited speakers, young researchers and 220 attendees mainly from Europe and North America. It was a unique opportunity to bring together the pioneers and leading immunologists in the fields of transplantation and cancer, focusing on shared mechanisms that control immune responses in organ or bone marrow transplantation and in cancer.

Global Complexity: Information, Chaos, and Control at ASIS 1996 Annual Meeting.

Science.gov (United States)

Jacob, M. E. L.

1996-01-01

Discusses proceedings of the 1996 ASIS (American Society for Information Science) annual meeting in Baltimore (Maryland), including chaos theory; electronic universities; distance education; intellectual property, including information privacy on the Internet; the need for leadership in libraries and information centers; information warfare and…

NIEHS/EPA Children's Environmental Health and Disease Prevention Research Centers: 2017 Annual Meeting Proceedings

Science.gov (United States)

The 2017 Annual Meeting of the NIEHS/EPA Children’s Environmental Health and Disease Prevention Research Centers was hosted by EPA in collaboration with NIEHS and the Pediatric Environmental Health Specialty Units (PEHSUs). The meeting was held at the EPA Region 9 offices i...

Proceedings of the Third Annual Information Meeting DOE Low-Level Waste-Management Program

Energy Technology Data Exchange (ETDEWEB)

Large, D.E.; Lowrie, R.S.; Stratton, L.E.; Jacobs, D.G. (comps.)

1981-12-01

The Third Annual Participants Information Meeting of the Low-Level Waste Management Program was held in New Orleans, Louisiana, November 4-6, 1981 The specific purpose was to bring together appropriate representatives of industry, USNRC, program management, participating field offices, and contractors to: (1) exchange information and analyze program needs, and (2) involve participants in planning, developing and implementing technology for low-level waste management. One hundred seven registrants participated in the meeting. Presentation and workshop findings are included in these proceedings under the following headings: low-level waste activities; waste treatment; shallow land burial; remedial action; greater confinement; ORNL reports; panel workshops; and summary. Forty-six papers have been abstracted and indexed for the data base.

Proceedings of the Third Annual Information Meeting DOE Low-Level Waste-Management Program

International Nuclear Information System (INIS)

Large, D.E.; Lowrie, R.S.; Stratton, L.E.; Jacobs, D.G.

1981-12-01

The Third Annual Participants Information Meeting of the Low-Level Waste Management Program was held in New Orleans, Louisiana, November 4-6, 1981 The specific purpose was to bring together appropriate representatives of industry, USNRC, program management, participating field offices, and contractors to: (1) exchange information and analyze program needs, and (2) involve participants in planning, developing and implementing technology for low-level waste management. One hundred seven registrants participated in the meeting. Presentation and workshop findings are included in these proceedings under the following headings: low-level waste activities; waste treatment; shallow land burial; remedial action; greater confinement; ORNL reports; panel workshops; and summary. Forty-six papers have been abstracted and indexed for the data base

International Working Group on Fast Reactors Thirteenth Annual Meeting. Summary Report. Part II

International Nuclear Information System (INIS)

1980-10-01

The Thirteenth Annual Meeting of the IAEA International Working Group on Fast Reactors was held at the IAEA Headquarters, Vienna, Austria from 9 to 11 April 1980. The Summary Report (Part I) contains the Minutes of the Meeting. The Summary Report (Part II) contains the papers which review the national programme in the field of LMFBRs and other presentations at the Meeting. The Summary Report (Part III) contains the discussions on the review of the national programmes

International Working Group on Fast Reactors Thirteenth Annual Meeting. Summary Report. Part I

International Nuclear Information System (INIS)

1980-09-01

The Thirteenth Annual Meeting of the IAEA International Working Group on Fast Reactors was held at the IAEA Headquarters, Vienna, Austria from 9 to 11 April 1980. The Summary Report (Part I) contains the Minutes of the Meeting. The Summary Report (Part II) contains the papers which review the national programme in the field of LMFBRs and other presentations at the Meeting. The Summary Report (Part III) contains the discussions on the review of the national programmes

International Working Group on Past Reactors Thirteenth Annual Meeting. Summary Report. Part III

International Nuclear Information System (INIS)

1981-04-01

The Thirteenth Annual Meeting of the IAEA International Working Group on Fast Reactors was held at the IAEA Headquarters, Vienna, Austria from 9 to 11 April 1980. The Summary Report (Part I) contains the Minutes of the Meeting. The Summary Report (Part II) contains the papers which review the national programme in the field of LMFBRs and other presentations at the Meeting. The Summary Report (Part III) contains the discussions on the review of the national programmes

Abstracts of the CGU Annual Scientific Meeting : Geospatial Processes : Integrating Pedosphere, Lithosphere and Hydrosphere

International Nuclear Information System (INIS)

Krebes, E.S.; Buttle, J.

2006-01-01

This annual scientific meeting of the Canadian Geophysical Union (CGU) was held jointly with the annual meeting of the Canadian Society of Soil Science (CSSS). The CGU sessions addressed topical issues such as hydrology; geoelectromagnetics; geodesy and geodynamics; earthquakes and natural hazards; environment and climate systems; geocomputations and visualization; glaciology; and general geophysics. The CSSS sessions addressed topical issues such as soil water; problem soils; northern issues; climate change; nutrient management; forest soils and management; land reclamation and remediation; and general soil science. The conference featured 311 oral presentations, of which 19 have been catalogued separately for inclusion in this database

117th Annual Meeting, Medical Library Association, Inc., Seattle, WA, May 26–31, 2017

Directory of Open Access Journals (Sweden)

Nicole Mitchell

2018-01-01

Full Text Available The Medical Library Association (MLA held its 117th annual meeting in Seattle, Washington, May 26–31, 2017, at the Washington State Convention Center. The meeting theme was “Dream, Dare, Do.”

1st Annual Meeting of the Future Circular Collider study

CERN Document Server

2015-01-01

This first Annual Meeting of the Future Circular Collider study is an important milestone to conclude the first, exploratory phase, leading to the identification of the baseline for the further study. Organized as an IEEE conference, it will provide the opportunity for re-enforcing the cohesion of the community and to catalyse cross-fertilization within the FCC study.

ABC-VED analysis of expendable medical stores at a tertiary care hospital.

Science.gov (United States)

Kumar, Sushil; Chakravarty, A

2015-01-01

The modern system of medicine has evolved into a complex, sophisticated and expensive treatment modality in terms of cost of medicines and consumables. In any hospital, approximately 33% of total annual budget is spent on buying materials and supplies including medicines. ABC (Always, Better Control)-VED (Vital, Essential, Desirable) analysis of medical stores of a large teaching, tertiary care hospital of the Armed Forces was carried out to identify the categories of drugs needing focused managerial control. Annual consumption and expenditure data of expendable medical stores for one year was extracted from the drug expense book, followed by classification on its annual usage value. Subsequently, the factor of criticality was applied to arrive at a decision matrix for understanding the need for selective managerial control. The study revealed that out of 1536 items considered for the study, 6.77% (104), 19.27% (296) and 73.95% (1136) items were found to be A, B and C category items respectively. VED analysis revealed that vital items (V) accounted for 13.14% (201), essential items (E) for 56.37% (866) and desirable accounted for 30.49% items (469). ABC-VED matrix analysis of the inventory reveals that only 322 (21%) items out of an inventory of 1536 drugs belonging to category I will require maximum attention. Scientific inventory management tools need to be applied routinely for efficient management of medical stores, as it contributes to judicious use of limited resources and resultant improvement in patient care.

TEDD Annual Meeting with 3D Bioprinting Workshop.

Science.gov (United States)

Raghunath, Michael; Rimann, Markus; Kopanska, Katarzyna S; Laternser, Sandra

2018-02-01

Bioprinting is the technology of choice for realizing functional tissues such as vascular system, muscle, cartilage and bone. In the future, bioprinting will influence the way we engineer tissues and bring it to a new level of physiological relevance. That was the topic of the 2017 TEDD Annual Meeting at ZHAW Waedenswil on 8th and 9th November. In an exciting workshop, the two companies regenHU Ltd. and CELLINK gave us an insight into highly topical applications and collaborations in this domain.

2004 Environmental Mutagen Society Annual Meeting - Genes, Mutations and Disease: The Environmental Connection

Energy Technology Data Exchange (ETDEWEB)

Samson, Leona D.

2004-08-23

The Meeting consisted of 9 Symposia, 4 Keynote Lectures, 3 Platform Sessions and 4 Poster Sessions. In addition there were Breakfast Meetings for Special Interest Groups designed to inform attendees about the latest advances in environmental mutagenesis research. Several of the topics to be covered at this broad meeting will be of interest to the Department of Energy, Office of Science. The relevance of this meeting to the DOE derives from the fact that low dose radiation may represent one of the most significant sources of human mutations that are attributable to the environment. The EMS membership, and those who attended the EMS Annual Meeting were interested in both chemical and radiation induced biological effects, such as cell death, mutation, teratogenesis, carcinogenesis and aging. These topics thate were presented at the 2004 EMS Annual meeting that were of clear interest to DOE include: human variation in cancer susceptibility, unusual mechanisms of mutation, germ and stem cell mutagenesis, recombination and the maintenance of genomic stability, multiple roles for DNA mismatch repair, DNA helicases, mutation, cancer and aging, Genome-wide transcriptional responses to environmental change, Telomeres and genomic stability: when ends don?t meet, systems biology approach to cell phenotypic decision processes, and the surprising biology of short RNAs. Poster and platform sessions addressed topics related to environmental mutagen exposure, DNA repair, mechanisms of mutagenesis, epidemiology, genomic and proteomics and bioinformatics. These sessions were designed to give student, postdocs and more junior scientists a chance to present their work.

Twelfth annual meeting of the International Working Group on Fast Reactors. Summary report. Part I

Energy Technology Data Exchange (ETDEWEB)

NONE

1979-05-01

The Twelfth Annual Meeting of the IWGFR was held in accordance with the recommendation of the previous AGM,in Vienna from 27 to 30 March 1979. The meeting was attended by the Member States of the group: France, the Federal Republic of Germany, Italy, Japan, the United Kingdom, and the USA, as well as by representatives from CEC, IAEA and OECD and observer from the USSR. This document includes: review of the IWGFR Activities for the period since the Eleventh Annual Meeting of the Group; preliminary programme of international conference on breeder reactors as a world energy resource and the breeder fuel cycle; list of meetings on atomic energy which may be of interest to the IWGFR Members; IWGFR criteria for supporting some of the international conferences; list of proposed topics for the IWGFR Specialists' Meetings; list of topics for review articles on LMFBR recommended for publication by the IAEA; list of meetings sponsored by the IWGFR; a list of members of the International Working Group on Fast Reactors.

Twelfth annual meeting of the International Working Group on Fast Reactors. Summary report. Part I

International Nuclear Information System (INIS)

1979-05-01

The Twelfth Annual Meeting of the IWGFR was held in accordance with the recommendation of the previous AGM,in Vienna from 27 to 30 March 1979. The meeting was attended by the Member States of the group: France, the Federal Republic of Germany, Italy, Japan, the United Kingdom, and the USA, as well as by representatives from CEC, IAEA and OECD and observer from the USSR. This document includes: review of the IWGFR Activities for the period since the Eleventh Annual Meeting of the Group; preliminary programme of international conference on breeder reactors as a world energy resource and the breeder fuel cycle; list of meetings on atomic energy which may be of interest to the IWGFR Members; IWGFR criteria for supporting some of the international conferences; list of proposed topics for the IWGFR Specialists' Meetings; list of topics for review articles on LMFBR recommended for publication by the IAEA; list of meetings sponsored by the IWGFR; a list of members of the International Working Group on Fast Reactors

The ABC transporters in Candidatus Liberibacter asiaticus.

Science.gov (United States)

Li, Wenlin; Cong, Qian; Pei, Jimin; Kinch, Lisa N; Grishin, Nick V

2012-11-01

Candidatus Liberibacter asiaticus (Ca. L. asiaticus) is a Gram-negative bacterium and the pathogen of Citrus Greening disease (Huanglongbing, HLB). As a parasitic bacterium, Ca. L. asiaticus harbors ABC transporters that play important roles in exchanging chemical compounds between Ca. L. asiaticus and its host. Here, we analyzed all the ABC transporter-related proteins in Ca. L. asiaticus. We identified 14 ABC transporter systems and predicted their structures and substrate specificities. In-depth sequence and structure analysis including multiple sequence alignment, phylogenetic tree reconstruction, and structure comparison further support their function predictions. Our study shows that this bacterium could use these ABC transporters to import metabolites (amino acids and phosphates) and enzyme cofactors (choline, thiamine, iron, manganese, and zinc), resist to organic solvent, heavy metal, and lipid-like drugs, maintain the composition of the outer membrane (OM), and secrete virulence factors. Although the features of most ABC systems could be deduced from the abundant experimental data on their orthologs, we reported several novel observations within ABC system proteins. Moreover, we identified seven nontransport ABC systems that are likely involved in virulence gene expression regulation, transposon excision regulation, and DNA repair. Our analysis reveals several candidates for further studies to understand and control the disease, including the type I virulence factor secretion system and its substrate that are likely related to Ca. L. asiaticus pathogenicity and the ABC transporter systems responsible for bacterial OM biosynthesis that are good drug targets. Copyright © 2012 Wiley Periodicals, Inc.

The fate of abstracts presented at the Australasian College of Dermatologists annual meetings from 2008 to 2012: A 5-year analysis

Directory of Open Access Journals (Sweden)

Aylin Ozturk Meral

2017-09-01

Conclusion: The annual meetings of the ACD have achieved a PR of 48.3% over 5 years with an average IF of 2.175 and a mean time to publication of 16.3 months, which is coequal to those of scientific meetings of other medical societies.

The use of active breathing control (ABC) to reduce margin for breathing motion

International Nuclear Information System (INIS)

Wong, John W.; Sharpe, Michael B.; Jaffray, David A.; Kini, Vijay R.; Robertson, John M.; Stromberg, Jannifer S.; Martinez, Alavro A.

1999-01-01

Purpose: For tumors in the thorax and abdomen, reducing the treatment margin for organ motion due to breathing reduces the volume of normal tissues that will be irradiated. A higher dose can be delivered to the target, provided that the risk of marginal misses is not increased. To ensure safe margin reduction, we investigated the feasibility of using active breathing control (ABC) to temporarily immobilize the patient's breathing. Treatment planning and delivery can then be performed at identical ABC conditions with minimal margin for breathing motion. Methods and Materials: An ABC apparatus is constructed consisting of 2 pairs of flow monitor and scissor valve, 1 each to control the inspiration and expiration paths to the patient. The patient breathes through a mouth-piece connected to the ABC apparatus. The respiratory signal is processed continuously, using a personal computer that displays the changing lung volume in real-time. After the patient's breathing pattern becomes stable, the operator activates ABC at a preselected phase in the breathing cycle. Both valves are then closed to immobilize breathing motion. Breathing motion of 12 patients were held with ABC to examine their acceptance of the procedure. The feasibility of applying ABC for treatment was tested in 5 patients by acquiring volumetric scans with a spiral computed tomography (CT) scanner during active breath-hold. Two patients had Hodgkin's disease, 2 had metastatic liver cancer, and 1 had lung cancer. Two intrafraction ABC scans were acquired at the same respiratory phase near the end of normal or deep inspiration. An additional ABC scan near the end of normal expiration was acquired for 2 patients. The ABC scans were also repeated 1 week later for a Hodgkin's patient. In 1 liver patient, ABC scans were acquired at 7 different phases of the breathing cycle to facilitate examination of the liver motion associated with ventilation. Contours of the lungs and livers were outlined when applicable

Estimation of the development possibility of the ABC/ATW fuel cycle based on LiF-BeF2 fuel salt. Part 2

International Nuclear Information System (INIS)

Bychkov, A.V.; Naumov, V.S.

1994-01-01

The aim of the first chapter was generalization of data on solubility and equilibrium states of fission product and actinide fluorides in fluoride salt melts-solvents and fuel composition melts based on LiF-BeF 2 mixture which was proposed as fuel basis for ABC/ATW facility. The second chapter is devoted to description of processes proposed for the chemical-technological complex of the ABC/ATW facility and their physico-chemical peculiarities. The complex is responsible for the removal of fission products and actinides from irradiated fuel salt

Joint annual meeting of the Swiss Physical and the Society Austrian Physical Society

CERN Document Server

2017-01-01

The next annual meeting, hosted by CERN, will take place from 21 - 25 August 2017 in Genève at two different locations. Starting at CERN on 21st with internal meetings of some of the participating societies, the 22nd will be dedicated to plenary and invited talks and more (see below). We will then move to the Centre International de Conférences de Genève (CICG) on 23 - 25 August where further plenary talks and all topical sessions will take place. The meeting is organised - as every two years - as a joint meeting with the Austrian Physical Society (ÖPG) and the Swiss Society for Astrophysics and Astronomy (SSAA). The Swiss Institute of Particle Physics (CHIPP) will participate additionally to their usual 2-year rhythm. We also welcome for the first time the NCCR MARVEL (Computational Design and Discovery of Novel Materials). They all together guarantee an exciting conference covering physics at its best. Many thanks go to CERN for their generous help and support with the organisation.

The ABC-paradox: is Time Driven ABC relevant for small and Medium sized enterprises (SME)?

DEFF Research Database (Denmark)

Fladkjær, Henrik Find; Jensen, Erling

Several articles suggest that Activity Based Costing (ABC) has failed to succeed in practical use. It is even argued that we have an ABC-paradox. Activity Based Costing has won theoretically in nu-merous articles in journals, through books, being included in all major Business Accounting text-books...

Molecular characterization of feline infectious peritonitis virus strain DF-2 and studies of the role of ORF3abc in viral cell tropism.

Science.gov (United States)

Bálint, Ádám; Farsang, Attila; Zádori, Zoltán; Hornyák, Ákos; Dencso, László; Almazán, Fernando; Enjuanes, Luis; Belák, Sándor

2012-06-01

The full-length genome of the highly lethal feline infectious peritonitis virus (FIPV) strain DF-2 was sequenced and cloned into a bacterial artificial chromosome (BAC) to study the role of ORF3abc in the FIPV-feline enteric coronavirus (FECV) transition. The reverse genetic system allowed the replacement of the truncated ORF3abc of the original FIPV DF-2 genome with the intact ORF3abc of the canine coronavirus (CCoV) reference strain Elmo/02. The in vitro replication kinetics of these two viruses was studied in CrFK and FCWF-4 cell lines, as well as in feline peripheral blood monocytes. Both viruses showed similar replication kinetics in established cell lines. However, the strain with a full-length ORF3 showed markedly lower replication of more than 2 log(10) titers in feline peripheral blood monocytes. Our results suggest that the truncated ORF3abc plays an important role in the efficient macrophage/monocyte tropism of type II FIPV.

The possibility of fuel cycle design for ABC/ATW complex with molten fuel on LiF-BeF{sub 2} basis

Energy Technology Data Exchange (ETDEWEB)

Naumov, V.S.; Bychkov, A.V. [Research Institute of Atomic Reactors, Dimitrovgrad (Russian Federation)

1995-10-01

The experience gained in the field of the development of molten salt reactors (MSR) can be made a basis of chemical processing of the ABC/ATW liquid fuel. The following combination of two processing principles are proposed for the ABC/ATW fuel (LiF-BeF{sub 2}-PuF{sub 3,(4)} - MAF{sub n}): - continious removal of radioactive gases, volatile impurities and {open_quotes}noble fission products{close_quotes}; - portion-by-portion electrochemical processing with removal of rare earth elements and some other fission products at an autonomous plant. After processing the fuel salt is brought back to the blanket of the ABC/ATW complex. The analysis of information previously published in different countries allows for a safe assumption that the ABC/ATW fuel cycle with liquid fuel salt is feasible and can be demonstrated experimentally.

Progress report on nuclear science and technology in China (Vol.2). Proceedings of academic annual meeting of China Nuclear Society in 2011, No.10--nuclear Information sub-volume

International Nuclear Information System (INIS)

2012-10-01

Progress report on nuclear science and technology in China (Vol. 2) includes 698 articles which are communicated on the second national academic annual meeting of China Nuclear Society. There are 10 books totally. This is the tenth one, the content is about nuclear Information and computer applications

MetaABC--an integrated metagenomics platform for data adjustment, binning and clustering.

Science.gov (United States)

Su, Chien-Hao; Hsu, Ming-Tsung; Wang, Tse-Yi; Chiang, Sufeng; Cheng, Jen-Hao; Weng, Francis C; Kao, Cheng-Yan; Wang, Daryi; Tsai, Huai-Kuang

2011-08-15

MetaABC is a metagenomic platform that integrates several binning tools coupled with methods for removing artifacts, analyzing unassigned reads and controlling sampling biases. It allows users to arrive at a better interpretation via series of distinct combinations of analysis tools. After execution, MetaABC provides outputs in various visual formats such as tables, pie and bar charts as well as clustering result diagrams. MetaABC source code and documentation are available at http://bits2.iis.sinica.edu.tw/MetaABC/ CONTACT: dywang@gate.sinica.edu.tw; hktsai@iis.sinica.edu.tw Supplementary data are available at Bioinformatics online.

Conversion rates of abstracts presented at the Canadian Rheumatology Association Annual Meetings into full-text journal articles.

Science.gov (United States)

Yacyshyn, Elaine A; Soong, Laura C

2017-06-01

Dissemination of research studies is important for research ideas to be transformed from initial abstracts to full publications. Analyses of the scientific impact and publication record of the Canadian Rheumatology Association (CRA) Annual meeting have not been previously described. This study determines the publication rate of abstracts presented at the CRA Annual Meetings 2005-2013 to full-text journal articles and the factors associated with publication. Program records of previous CRA meetings from 2005 to 2013 were obtained. Abstracts were searched for corresponding full-text publication in Google Scholar and PubMed using a search algorithm. Abstracts and subsequent published articles were evaluated for type of abstract, time to publication, study type, publishing journal, and journal impact factor. A total of 1401 abstracts were included in the study, 567 of which were converted to full publications. The average time to publication was 19.7 months, with 89% of abstracts published within 3 years of being presented. Eighty-three percent of abstracts were clinical in nature, and 58% of published studies were observational in design. Articles were published in a wide range of journals, with the top publisher being the Journal of Rheumatology (31%). Average time to publication was 19.7 months. Eighty-six percent of articles had a Journal Impact Factor > 2. Overall, 40.5% of abstracts presented at the CRA Annual Meetings 2005-2013 were published. Further research is needed to determine barriers and reasons for abstracts not being published as full-text articles.

Sommelier Suggestions: The Arthroscopy Association of North America Annual Meeting Inspires a Content Collection Worth Tasting.

Science.gov (United States)

Hunt, Timothy J; Brand, Jefferson C; Provencher, Matthew T; Rossi, Michael J; Lubowitz, James H

2017-05-01

The 2017 Arthroscopy Association of North America Annual Meeting Program inspires a Content Collection of Arthroscopy journal articles worthy of review. A foundation of a credible podium presentation is the published medical literature. Your Editors thus suggest recent publications that seem particularly relevant in the context of the 2017 annual meeting. Consider these articles as one would a suggestion for a good glass of wine to complement a delicious meal. Copyright © 2017 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

Abstracts from the fourth annual meeting of the council on ionizing radiation measurements and standards (CIRMS)

International Nuclear Information System (INIS)

Anon.

1995-01-01

The Council on Ionizing Radiation Measurements and Standards held its fourth annual meeting at the National Institute of Standards and Technology, Gaithersburg, Maryland on November 28-30, 1995. The organization represents thousands of users of ionizing radiation and radioactive sources engaged in industrial radiation processing and sterilization, medical radiation diagnostics and therapy, nuclear power, and worker radiation protection programs. CIRMS provides a forum for discussing ionizing radiation issues; identifying, defining and prioritizing needed work; disseminating information on standards; and organizing workshops and meetings to advance ionizing radiation technology. Over 100 participants attended the meeting, which highlighted advanced techniques in radiation dosimetry and radioactivity measurements for the different ionizing radiation communities. Representatives attended from 28 corporations, 10 federal agencies, 8 national laboratories, 12 universities, and 1 state. Advanced techniques and future measurement needs were discussed in four sessions: (I) Medical Dosimetry, Radiology and Nuclear Medicine, (II) Occupational and Radiation Protection Dosimetry, (III) Measurement Techniques for Public and Environmental Radiation Protection, and (IV) Measurement Techniques for Radiation Effects on Materials. An additional session (Session V) was added to this annual meeting on the implementation of ISO 9000 for those CIRMS members involved in instrument and product manufacturing, and those providing radiation measurement services. Abstracts are also included from the poster session (Session VI) held on the final day of the meeting. The 4th Annual Meeting was organized by the Chairman of the Science and Technology Committee, Mr. Joseph C. McDonald of the Battelle Pacific Northwest Laboratory

ABC versus CAB for cardiopulmonary resuscitation: a prospective, randomized simulator-based trial.

Science.gov (United States)

Marsch, Stephan; Tschan, Franziska; Semmer, Norbert K; Zobrist, Roger; Hunziker, Patrick R; Hunziker, Sabina

2013-09-06

After years of advocating ABC (Airway-Breathing-Circulation), current guidelines of cardiopulmonary resuscitation (CPR) recommend CAB (Circulation-Airway-Breathing). This trial compared ABC with CAB as initial approach to CPR from the arrival of rescuers until the completion of the first resuscitation cycle. 108 teams, consisting of two physicians each, were randomized to receive a graphical display of either the ABC algorithm or the CAB algorithm. Subsequently teams had to treat a simulated cardiac arrest. Data analysis was performed using video recordings obtained during simulations. The primary endpoint was the time to completion of the first resuscitation cycle of 30 compressions and two ventilations. The time to execution of the first resuscitation measure was 32 ± 12 seconds in ABC teams and 25 ± 10 seconds in CAB teams (P = 0.002). 18/53 ABC teams (34%) and none of the 55 CAB teams (P = 0.006) applied more than the recommended two initial rescue breaths which caused a longer duration of the first cycle of 30 compressions and two ventilations in ABC teams (31 ± 13 vs.23 ± 6 sec; P = 0.001). Overall, the time to completion of the first resuscitation cycle was longer in ABC teams (63 ± 17 vs. 48 ± 10 sec; P ABC with an earlier start of CPR and a shorter time to completion of the first 30:2 resuscitation cycle. These findings endorse the change from ABC to CAB in international resuscitation guidelines.

2010 ANNUAL MEETING ON NUCLEAR TECHNOLOGY. Pt. 4. Section reports

International Nuclear Information System (INIS)

Berlepsch, Thilo v.; Hering, Wolfgang

2011-01-01

Summary report on 2 Sessions of Section: - New Build and Innovations (Section 12) of the ANNUAL MEETING On NUCLEAR TECHNOLOGY held in Berlin on May 4 to 6, 2010. The other Sections 'Reactor Physics and Methods of Calculation (Section 1)', 'Thermodynamics and Fluid Dynamics (Section 2)', 'Safety of Nuclear Installations - Methods, Analysis, Results (Section 3)', 'Front End and Back End of the Fuel Cycle, Radioactive Waste, Storage (Section 4)', 'Front End of the Fuel Cycle, Fuel Elements and Core Components (Section 5)', 'Operation of Nuclear Installations (Section 6)', 'Decommissioning of Nuclear Installations (Section 7)', 'Fusion Technology (Section 8)', 'Energy Industry and Economics (Section 10)', 'Radiation Protection (Section 11)', 'New Build and Innovations (Session New Build and Innovations, Section 12)', and 'Education, Expert Knowledge, Know-how-Transfer (Section 13)' have been covered in atw issues 10, 11 and 12 (2010). (orig.)

ABC transporters in fish species: a review

Directory of Open Access Journals (Sweden)

Marta eFerreira

2014-07-01

Full Text Available ATP-binding cassette (ABC proteins were first recognized for their role in multidrug resistance (MDR in chemotherapeutic treatments, which is a major impediment for the successful treatment of many forms of malignant tumors in humans. These proteins, highly conserved throughout vertebrate species, were later related to cellular detoxification and accounted as responsible for protecting aquatic organisms from xenobiotic insults in the so-called multixenobiotic resistance mechanism (MXR. In recent years, research on these proteins in aquatic species has highlighted their importance in the detoxification mechanisms in fish thus it is of extreme added value to continue these studies. Several transporters have been pointed out as relevant in the ecotoxicological context associated to the transport of xenobiotics, such as P-glycoproteins (Pgps, multidrug-resistance-associated proteins (MRPs 1-5 and breast resistance associated protein (BCRP. In mammals, several nuclear receptors have been identified as mediators of phase I and II metabolizing enzymes and ABC transporters. In aquatic species, knowledge on co-regulation of detoxification mechanism is scarce and needs to be addressed. The interaction of emergent contaminants, with chemosensitizer potential, with ABC transporters in aquatic organisms can compromise detoxification processes and have population effects and should be studied in more detail. This review intends to summarize the recent advances in research on MXR mechanisms in fish species, focusing in 1 regulation and functioning of ABC proteins; 2 cooperation with phase I and II biotransformation enzymes; and 3 ecotoxicological relevance and information on emergent pollutants with ability to modulate ABC transporters expression and activity. Several lines of evidence are clear suggesting the important role of these transporters in detoxification mechanisms and must be further investigated in fish.

Chemiluminescence Immunoassay for the Detection of Antibodies against the 2C and 3ABC Nonstructural Proteins Induced by Infecting Pigs with Foot-and-Mouth Disease Virus.

Science.gov (United States)

Liu, Zezhong; Shao, Junjun; Zhao, Furong; Zhou, Guangqing; Gao, Shandian; Liu, Wei; Lv, Jianliang; Li, Xiumei; Li, Yangfan; Chang, Huiyun; Zhang, Yongguang

2017-08-01

The potential diagnostic value of chemiluminescence immunoassays (CLIAs) has been accepted in recent years, although their use for foot-and-mouth disease (FMD) diagnostics has not been reported. Full-length 3ABC and 2C proteins were expressed in bacteria and purified by affinity chromatography to develop a rapid and accurate approach to distinguish pigs infected with foot-and-mouth disease virus (FMDV) from vaccinated pigs. The recombinant proteins were then used as antigens to develop two CLIAs for the detection of antibodies against nonstructural viral proteins. The diagnostic performance of the two assays was compared by analyzing serum from pigs (naive pigs, n = 63; vaccinated, uninfected pigs, n = 532; naive, infected pigs, n = 117) with a known infection status. The 3ABC-2C CLIA had a higher accuracy rate, with a diagnostic sensitivity of 100% and a diagnostic specificity of 96.5%, than the 3ABC CLIA, which had a diagnostic sensitivity of 95.7% and a diagnostic specificity of 96.0%. The results of the 3ABC-2C CLIA also had a high rate of concordance with those of two commercial FMDV enzyme-linked immunosorbent assay (ELISA) kits used to assess serum collected from 962 pigs in the field (96.2% and 97.8%, respectively). The 3ABC-2C CLIA detected infection in serum samples from infected pigs earlier than the commercial ELISA kits. In addition, the 3ABC-2C CLIA produced results within 15 min. On the basis of these findings, the 3ABC-2C CLIA could serve as the foundation for the development of penside FMD diagnostics and offers an alternative method to detect FMDV infections. Copyright © 2017 American Society for Microbiology.

Proceedings of the Efficient Separations and Processing Cross-Cutting Program Annual Technical Exchange Meeting

International Nuclear Information System (INIS)

1995-01-01

This document contains summaries of technology development presented at the 1995 Efficient Separations and Processing Cross-Cutting Program (ESP) Annual Technical Exchange Meeting. The ESP is sponsored by the US Department of Energy's Office of Environmental Management (EM), Office of Technology Development. The meeting is held annually to promote a free exchange of ideas among technology developers, potential users (for example, EM focus areas), and other interested parties within EM. During this meeting, developers of ESP-funded technologies describe the problems and needs addressed by their technologies; the technical approach, accomplishments, and resolution of issues; the strategy and schedule for commercialization; and evolving potential applications. Presenters are asked to address the following areas: Target waste management problem, waste stream, or data need; scientific background and technical approach; technical accomplishments and resolution of technical issues; schedule and strategy for commercializing and implementing the technology or acquiring needed data; potential alternate applications of the technology or data, including outside of DOE/EM. The meeting is not a program review of the individual tasks or subtasks; but instead focuses on the technical aspects and implementation of ESP-sponsored technology or data. The meeting is also attended by members of the ESP Technical Review Team, who have the opportunity at that time to review the ESP as a whole

Abstracts from the 32nd Annual Scientific Meeting of the Canadian Geriatrics Society Quebec City, April 2012

OpenAIRE

Auais, M.; Morin, S.; Finch, L.; Sara, A.; Mayo, N.; Charise, A.; Islam, A.; Muir, Susan; Montero-Odasso, Manuel; Kennedy, C.C.; Papaioannou, A.; Ioannidis, G.; Giangregorio, L.M.; Adachi, J.D.; Thabane, L.

2012-01-01

The opinions expressed in the abstracts are those of the authors and are not to be construed as the opinion of the publisher (Canadian Geriatrics Society) or the organizers of the 32nd Annual Scientific Meeting of the Canadian Geriatrics Society. Although the publisher (Canadian Geriatrics Society) has made every effort to accurately reproduce the abstracts, the Canadian Geriatrics Society and the 32nd Annual Scientific Meeting of the Canadian Geriatrics Society assumes no responsibility and/...

Export of recombinant proteins in Escherichia coli using ABC transporter with an attached lipase ABC transporter recognition domain (LARD

Directory of Open Access Journals (Sweden)

Moon Yuseok

2009-01-01

Full Text Available Abstract Background ATP binding cassette (ABC transporter secretes the protein through inner and outer membranes simultaneously in gram negative bacteria. Thermostable lipase (TliA of Pseudomonas fluorescens SIK W1 is secreted through the ABC transporter. TliA has four glycine-rich repeats (GGXGXD in its C-terminus, which appear in many ABC transporter-secreted proteins. From a homology model of TliA derived from the structure of P. aeruginosa alkaline protease (AprA, lipase ABC transporter domains (LARDs were designed for the secretion of fusion proteins. Results The LARDs included four glycine-rich repeats comprising a β-roll structure, and were added to the C-terminus of test proteins. Either Pro-Gly linker or Factor Xa site was added between fusion proteins and LARDs. We attached different length of LARDs such as LARD0, LARD1 or whole TliA (the longest LARD to three types of proteins; green fluorescent protein (GFP, epidermal growth factor (EGF and cytoplasmic transduction peptide (CTP. These fusion proteins were expressed in Escherichia coli together with ABC transporter of either P. fluorescens or Erwinia chrysanthemi. Export of fusion proteins with the whole TliA through the ABC transporter was evident on the basis of lipase enzymatic activity. Upon supplementation of E. coli with ABC transporter, GFP-LARDs and EGF-LARDs were excreted into the culture supernatant. Conclusion The LARDs or whole TliA were attached to C-termini of model proteins and enabled the export of the model proteins such as GFP and EGF in E. coli supplemented with ABC transporter. These results open the possibility for the extracellular production of recombinant proteins in Pseudomonas using LARDs or TliA as a C-terminal signal sequence.

Cutting edge SRU control : improved environmental compliance with Jacobs advanced burner control+ (ABC+)

Energy Technology Data Exchange (ETDEWEB)

Molenaar, G. [Jacobs Canada Inc., Calgary, AB (Canada); Henning, A.; Kobussen, S. [Jacobs Nederland BV, Hoogvliet (Netherlands)

2009-07-01

Oil sands bitumen contains approximately 4 to 5 per cent sulphur by weight and the bitumen is upgraded to produce lighter fractions. During coking the bitumen is heated and cracked into lighter molecules and a mixture of kerosene, naphtha and gas oil is recovered via fractionation. Then, the vapors leaving the fractionator are processed through hydrodesulphurization, followed by removal by amine based sweetening units. The acid gas from the ASUs is sent to the sulphur recovery units (SRUs) where most of the sulphur is recovered as elemental sulphur. The oil sands industry faces many challenges with respect to environmental impact, energy use and greenhouse gas emissions including the recovery of sulphur and minimizing hydrogen sulfide (H{sub 2}S) and sulphur dioxide (SO{sub 2}) emissions from the oil sands production facilities. In order to improve the SRU control response to acid gas feed variations, Jacobs Comprimo Sulphur Solutions implemented advanced burner control+ (ABC+) at Suncor's Simonette Gas Plant's SRU in northern Alberta. This control system used an acid gas feed analyzer and dynamic algorithms to control the combustion air to the reaction furnace. The analyzer measures H{sub 2}S, total hydrocarbons, carbon dioxide (CO{sub 2}) and water (H{sub 2}O) accurately and quickly, which is important for having effective and fast air-to-acid gas ratio control. The paper provided background information on the Suncor Simonette Gas Plant and discussed ABC+ versus conventional control. An overview of the simplified ABC and ABC+ systems was then illustrated and presented. The ABB multiwave process photometer was also explained. Last, a dynamic simulation of the potential benefits of ABC+ was discussed and the ABC+ benefits for oil sands were presented. It was concluded that ABC+ provides improved SRU performance, reduced SO{sub 2} emissions and violations, and reduced flaring. 1 tab., 3 figs.

Highlights of the XXI annual meeting of the Brazilian Society of Protozoology, the XXXII annual meeting on Basic Research in Chagas' disease & an international symposium on vesicle trafficking in parasitic Protozoa – 7 to 9 November 2005, Caxambu, Minas Gerais, Brazil

Science.gov (United States)

Shaw, Jeffrey; Schenkman, Sergio; Rodrigues, Mauricio Martins

2006-01-01

This report focuses on the 2005 Annual meeting held in Caxambu, Minas Gerais, Brazil that was convened and organized by the Brazilian Society of Protozoology . This is an annual event and details of these meetings can be found on the Society's website. Within the space available it has been impossible to cover all the important and fascinating contributions and what is presented are our personal views of the meetings scientific highlights and new developments. The contents undoubtedly reflect each author's scientific interests and expertise. Fuller details of the round tables, seminars and posters can be consulted on line at . PMID:16916462

abc: An extensible AspectJ compiler

DEFF Research Database (Denmark)

Avgustinov, Pavel; Christensen, Aske Simon; Hendren, Laurie

2005-01-01

checking and code generation, as well as data flow and control flow analyses. The AspectBench Compiler (abc) is an implementation of such a workbench. The base version of abc implements the full AspectJ language. Its frontend is built, using the Polyglot framework, as a modular extension of the Java...... language. The use of Polyglot gives flexibility of syntax and type checking. The backend is built using the Soot framework, to give modular code generation and analyses. In this paper, we outline the design of abc, focusing mostly on how the design supports extensibility. We then provide a general overview...

Implementation of ABC method in real company

OpenAIRE

Kazhimova, Dina

2014-01-01

The aim of this Bachelor thesis is a thorough analysis of the modern calculation method Activity-based costing (ABC), that identifies the activities that a firm performs, and then assigns indirect costs to products. An ABC system recognizes the relationship between costs, activities and products, and through this relationship assigns indirect costs to products less arbitrarily than traditional methods. Comparison ABC method with traditional methods of cost allocation. Basing on the knowledge ...

Evolutionary Trajectories of Entomopathogenic Fungi ABC Transporters.

Science.gov (United States)

Baral, Bikash

2017-01-01

The ABC protein superfamily-also called traffic ATPases-are energy-dependent ubiquitous proteins, representing one of the crucial and the largest family in the fungal genomes. The ATP-binding cassette endows a characteristic 200-250 amino acids and is omnipresent in all organisms ranging from prokaryotes to eukaryotes. Unlike in bacteria with nutrient import functions, ABC transporters in fungal entomopathogens serve as effective efflux pumps that are largely involved in the shuttle of metabolites across the biological membranes. Thus, the search for ABC proteins may prove of immense importance in elucidating the functional and molecular mechanism at the host-pathogen (insect-fungus) interface. Their sequence homology, domain topology, and functional traits led to the actual identification of nine different families in fungal entomopathogens. Evolutionary relationships within the ABC superfamily are discussed, concentrating on computational approaches for comparative identification of ABC transporters in insect-pathogenic fungi (entomopathogens) with those of animals, plants, and their bacterial orthologs. Ancestors of some fungal candidates have duplicated extensively in some phyla, while others were lost in one lineage or the other, and predictions for the cause of their duplications and/or loss in some phyla are made. ABC transporters of fungal insect-pathogens serve both defensive and offensive functions effective against land-dwelling and ground foraging voracious insects. This study may help to unravel the molecular cascades of ABC proteins to illuminate the means through which insects cope with fungal infection and fungal-related diseases. Copyright © 2017 Elsevier Inc. All rights reserved.

Playware ABC: Engineering Play for Everybody

DEFF Research Database (Denmark)

Lund, Henrik Hautop

2017-01-01

This paper describes the Playware ABC concept, and how it allows anybody, anywhere, anytime to be building bodies and brains, which facilitates users to construct, combine and create. The Playware ABC concept focuses engineering and IT system development on creating solutions that are usable by a...

Review of the 25th annual scientific meeting of the International Society for Biological Therapy of Cancer.

Science.gov (United States)

Balwit, James M; Kalinski, Pawel; Sondak, Vernon K; Coulie, Pierre G; Jaffee, Elizabeth M; Gajewski, Thomas F; Marincola, Francesco M

2011-05-12

Led by key opinion leaders in the field, the 25th Annual Meeting of the International Society for Biological Therapy of Cancer (iSBTc, recently renamed the Society for Immunotherapy of Cancer, SITC) provided a scientific platform for ~500 attendees to exchange cutting-edge information on basic, clinical, and translational research in cancer immunology and immunotherapy. The meeting included keynote addresses on checkpoint blockade in cancer therapy and recent advances in therapeutic vaccination against cancer induced by Human Papilloma Virus 16. Participants from 29 countries interacted through oral presentations, panel discussions, and posters on topics that included dendritic cells and cancer, targeted therapeutics and immunotherapy, innate/adaptive immune interplay in cancer, clinical trial endpoints, vaccine combinations, countering negative regulation, immune cell trafficking to tumor microenvironment, and adoptive T cell transfer. In addition to the 50 oral presentations and >180 posters on these topics, a new SITC/iSBTc initiative to create evidence-based Cancer Immunotherapy Guidelines was announced. The SITC/iSBTc Biomarkers Taskforce announced the release of recommendations on immunotherapy biomarkers and a highly successful symposium on Immuno-Oncology Biomarkers that took place on the campus of the National Institutes of Health (NIH) immediately prior to the Annual Meeting. At the Annual Meeting, the NIH took the opportunity to publicly announce the award of the U01 grant that will fund the Cancer Immunotherapy Trials Network (CITN). In summary, the Annual Meeting gathered clinicians and scientists from academia, industry, and regulatory agencies from around the globe to interact and exchange important scientific advances related to tumor immunobiology and cancer immunotherapy.

Report of international symposium on the 22nd Japan annual nuclear energy meeting, PNC general meeting and business report about nuclear energy

Energy Technology Data Exchange (ETDEWEB)

NONE

1989-04-15

This conference report consists of three parts, which report the 22nd annual nuclear energy meeting in Japan, including the list of Korean delegates, program and the contents of five session, the conference report for PNC general meeting and the report on international symposium for fruition of nuclear power business. It introduces the main conception and the contents of the symposium.

An ABC analysis for power generation project

OpenAIRE

Batool Hasani; Younos Vakilalroaia

2013-01-01

One of the primary concerns on performance measurement is to know how much a particular project cost. However, using traditional method on project-based products often leads to inappropriate results. In this paper, we re-examine this issue by comparing the cost of a power station construction project using ABC versus traditional method. The results of survey show that ABC method is capable of providing better estimates for overhead costs compared with traditional method. In other words, ABC m...

12th Quadrennial Congress of the International Association for Radiation Research incorporating the 50th Annual Meeting of Radiation Research Society, RANZCR Radiation Oncology Annual Scientific Meeting and AINSE Radiation Science Conference

International Nuclear Information System (INIS)

2003-01-01

The 12th International Congress of Radiation Research (ICRR2003), for the first time held in the Southern Hemisphere under the auspices of the International Association of Radiation Research (IARR). The Australian affiliate of IARR is the Australian Institute of Nuclear Science and Engineering (AINSE). As with recent Congresses, the annual scientific meeting of the Radiation Research Society will be incorporated into the program. The Congress will be further enhanced by the integration of the annual scientific meeting of the Faculty of Radiation Oncology of the Royal Australian and New Zealand College of Radiologists, and the AINSE Radiation Science Conference. An exciting programme was presented with the main threads being radiation oncology, radiation biology, radiation chemistry/physics, radiation protection and the environment. Items in INIS scope have been separately indexed

Proceedings of the 26th annual meeting of the National Council on Radiation Protection Measurements

International Nuclear Information System (INIS)

Richmond, C.R.

1991-01-01

This book reports on the 26th Annual Meeting of the National Council on Radiation Protection and Measurements which addressed the topic Health and Ecological Implications of Radioactively Contaminated Environments, a topic of great current interest and importance. The meeting was divided into five subtopics. The first dealt with the contaminated sites themselves, the second with human health implications, the third on remediation, the fourth (a panel) on lessons learned and issues of the future and finally a summation. The meeting also included progress reports on the work of three NCRP committees, Scientific Committee 1-2 on the Assessment of Risk for Radiation Protection Purposes, Scientific Committee 66 on Biological Effects and Exposure Criteria for Ultrasound and Scientific Committee 83 on Identification of Research Needs for Radiation Protection. Summaries of these reports prepared by their respective chairmen are included in this volume

Benzene-derived N2-(4-hydroxyphenyl)-deoxyguanosine adduct: UvrABC incision and its conformation in DNA

Energy Technology Data Exchange (ETDEWEB)

Hang, Bo; Rodriguez, Ben; Yang, Yanu; Guliaev, Anton B.; Chenna, Ahmed

2010-06-14

Benzene, a ubiquitous human carcinogen, forms DNA adducts through its metabolites such as p-benzoquinone (p-BQ) and hydroquinone (HQ). N(2)-(4-Hydroxyphenyl)-2'-deoxyguanosine (N(2)-4-HOPh-dG) is the principal adduct identified in vivo by (32)P-postlabeling in cells or animals treated with p-BQ or HQ. To study its effect on repair specificity and replication fidelity, we recently synthesized defined oligonucleotides containing a site-specific adduct using phosphoramidite chemistry. We here report the repair of this adduct by Escherichia coli UvrABC complex, which performs the initial damage recognition and incision steps in the nucleotide excision repair (NER) pathway. We first showed that the p-BQ-treated plasmid was efficiently cleaved by the complex, indicating the formation of DNA lesions that are substrates for NER. Using a 40-mer substrate, we found that UvrABC incises the DNA strand containing N(2)-4-HOPh-dG in a dose- and time-dependent manner. The specificity of such repair was also compared with that of DNA glycosylases and damage-specific endonucleases of E. coli, both of which were found to have no detectable activity toward N(2)-4-HOPh-dG. To understand why this adduct is specifically recognized and processed by UvrABC, molecular modeling studies were performed. Analysis of molecular dynamics trajectories showed that stable G:C-like hydrogen bonding patterns of all three Watson-Crick hydrogen bonds are present within the N(2)-4-HOPh-G:C base pair, with the hydroxyphenyl ring at an almost planar position. In addition, N(2)-4-HOPh-dG has a tendency to form more stable stacking interactions than a normal G in B-type DNA. These conformational properties may be critical in differential recognition of this adduct by specific repair enzymes.

Glycolysis inhibition inactivates ABC transporters to restore drug sensitivity in malignant cells.

Directory of Open Access Journals (Sweden)

Ayako Nakano

Full Text Available Cancer cells eventually acquire drug resistance largely via the aberrant expression of ATP-binding cassette (ABC transporters, ATP-dependent efflux pumps. Because cancer cells produce ATP mostly through glycolysis, in the present study we explored the effects of inhibiting glycolysis on the ABC transporter function and drug sensitivity of malignant cells. Inhibition of glycolysis by 3-bromopyruvate (3BrPA suppressed ATP production in malignant cells, and restored the retention of daunorubicin or mitoxantrone in ABC transporter-expressing, RPMI8226 (ABCG2, KG-1 (ABCB1 and HepG2 cells (ABCB1 and ABCG2. Interestingly, although side population (SP cells isolated from RPMI8226 cells exhibited higher levels of glycolysis with an increased expression of genes involved in the glycolytic pathway, 3BrPA abolished Hoechst 33342 exclusion in SP cells. 3BrPA also disrupted clonogenic capacity in malignant cell lines including RPMI8226, KG-1, and HepG2. Furthermore, 3BrPA restored cytotoxic effects of daunorubicin and doxorubicin on KG-1 and RPMI8226 cells, and markedly suppressed subcutaneous tumor growth in combination with doxorubicin in RPMI8226-implanted mice. These results collectively suggest that the inhibition of glycolysis is able to overcome drug resistance in ABC transporter-expressing malignant cells through the inactivation of ABC transporters and impairment of SP cells with enhanced glycolysis as well as clonogenic cells.

ESNA: European Society for New Methods in Agricultural Research. 23. annual meeting and 3. German meeting on food irradiation. Book of abstracts

International Nuclear Information System (INIS)

1993-01-01

The book comprises 181 abstracts of the 23rd Annual Meeting of the European Society for New Methods in Agricultural Research and the 3rd German Meeting on Food Irradiation. The following subjects were discussed in six workshops: Radiation Technology and 3rd German Meeting on Food Irradiation (44); Advanced Methods in Animal Sciences (17); Soil-Plant Relationships (36); Plant Genetics, Breeding and Physiology (48); Environmental Aspects and Energy Use (16); Pest Management (20). The abstracts are supplemented by an alphabetic index of authors. (UHE) [de

ABC transporters affect the elimination and toxicity of CdTe quantum dots in liver and kidney cells

Energy Technology Data Exchange (ETDEWEB)

Chen, Mingli; Yin, Huancai; Bai, Pengli [CAS Key Lab of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu 215163 (China); Miao, Peng [CAS Key Lab of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu 215163 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Deng, Xudong [Department of Chemical Engineering, McMaster University, Hamilton, Ontario, L8S 4L7 (Canada); Xu, Yingxue [CAS Key Lab of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu 215163 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Hu, Jun [CAS Key Lab of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu 215163 (China); Yin, Jian, E-mail: yinj@sibet.ac.cn [CAS Key Lab of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu 215163 (China)

2016-07-15

This paper aimed to investigate the role of adenosine triphosphate-binding cassette (ABC) transporters on the efflux and the toxicity of nanoparticles in liver and kidney cells. In this study, we synthesized CdTe quantum dots (QDs) that were monodispersed and emitted green fluorescence (maximum peak at 530 nm). Such QDs tended to accumulate in human hepatocellular carcinoma cells (HepG2), human kidney cells 2 (HK-2), and Madin-Darby canine kidney (MDCK) cells, and cause significant toxicity in all the three cell lines. Using specific inhibitors and inducers of P-glycoprotein (Pgp) and multidrug resistance associated proteins (Mrps), the cellular accumulation and subsequent toxicity of QDs in HepG2 and HK-2 cells were significantly affected, while only slight changes appeared in MDCK cells, corresponding well with the functional expressions of ABC transporters in cells. Moreover, treatment of QDs caused concentration- and time- dependent induction of ABC transporters in HepG2 and HK-2 cells, but such phenomenon was barely found in MDCK cells. Furthermore, the effects of CdTe QDs on ABC transporters were found to be greater than those of CdCl{sub 2} at equivalent concentrations of cadmium, indicating that the effects of QDs should be a combination of free Cd{sup 2+} and specific properties of QDs. Overall, these results indicated a strong dependence between the functional expressions of ABC transporters and the efflux of QDs, which could be an important reason for the modulation of QDs toxicity by ABC transporters. - Highlights: • ABC transporters contributed actively to the cellular efflux of CdTe quantum dots. • ABC transporters affected the cellular toxicity of CdTe quantum dots. • Treatment of CdTe quantum dots induced the gene expression of ABC transporters. • Free Cd{sup 2+} should be partially involved in the effects of QDs on ABC transporters. • Cellular efflux of quantum dots could be an important modulator for its toxicity.

Costeo ABC - Gestión ABM

OpenAIRE

Cuevas Villegas, Carlos Fernando

2010-01-01

El presente artículo pretende mostrar en forma práctica la problemática de los sistemas actuales de costeo y plantear la alternativa conocida como costeo ABC, sus fundamentos, dificultades y utilidad. Así mismo se enfatiza el uso de la llamada Gerencia ABM, como complemento del costeo ABC.

XXXVIII Annual meeting of the Argentine Association of Nuclear Technology (AATN 2011)

International Nuclear Information System (INIS)

2011-01-01

The 38th Annual meeting of the Argentine Association of Nuclear Technology was organized by the AATN (Asociacion Argentina de Tecnologia Nuclear) in Buenos Aires, Argentine, between the 14 and 18 November of 2011. In this event 146 papers in 16 Sessions, with 13 Plenary Conferences and 3 Roundtables were presented. [es

The Fate of Abstracts Presented at the 2013 and 2014 Annual Meetings of the Romanian Society of Gastroenterology and Hepatology.

Science.gov (United States)

Trifan, Anca; Chihaia, Catalin-Alexandru; Tanase, Oana; Lungu, Cristina-Maria; Stanciu, Carol

2016-12-01

Oral and poster presentations at annual national meetings of the Romanian Society of Gastroenterology and Hepatology (RSGH) provide a forum for education, communication and discussion of new research. However, for the wide-spread dissemination of the new research work, each presentation should be subsequently published as a full-text article in peer-reviewed, indexed journals. to evaluate the publication rate of full-text articles in peer-reviewed journals after being first presented as abstracts at two consecutive RSGH annual meetings. A retrospective review of all abstracts presented at the annual meetings in 2013 and 2014 was performed. PubMed and Google Scholar were searched using abstract titles, first author's name and affiliation, and key words from the title to identify whether an abstract resulted in a peer-reviewed publication. Abstracts published in full-text were subsequently assessed for study type, study center, topics, publication year, journals and their impact factors (IFs). We chose the 2013 and 2014 meetings to ensure a minimum two-year follow-up period since the last meeting for the publication as full-length articles. A total of 562 abstracts were presented (275 in 2013, 287 in 2014). There were 150 oral presentations (93 in 2013, 57 in 2014) and 412 poster presentations (182 in 2013, 230 in 2014). Fifty seven of them (10.1%) were published as full-text articles, among them 26 (17.3%) after oral presentations and 31 (7.5%) after poster presentations (P=0.001). University affiliation and original research work were most likely to be published. The average IFs of the journals which published the articles were 2.42 in 2013 and 1.87 in 2014. The publication rate for the annual RSGH meetings abstracts as full-text articles in peer-reviewed journals is very low compared to the analyses performed in gastroenterology or other medical specialities from other countries. It is not clear yet what are the factors responsible for the failure of publication.

Review of the 25th annual scientific meeting of the International Society for Biological Therapy of Cancer

Directory of Open Access Journals (Sweden)

Jaffee Elizabeth M

2011-05-01

Full Text Available Abstract Led by key opinion leaders in the field, the 25th Annual Meeting of the International Society for Biological Therapy of Cancer (iSBTc, recently renamed the Society for Immunotherapy of Cancer, SITC provided a scientific platform for ~500 attendees to exchange cutting-edge information on basic, clinical, and translational research in cancer immunology and immunotherapy. The meeting included keynote addresses on checkpoint blockade in cancer therapy and recent advances in therapeutic vaccination against cancer induced by Human Papilloma Virus 16. Participants from 29 countries interacted through oral presentations, panel discussions, and posters on topics that included dendritic cells and cancer, targeted therapeutics and immunotherapy, innate/adaptive immune interplay in cancer, clinical trial endpoints, vaccine combinations, countering negative regulation, immune cell trafficking to tumor microenvironment, and adoptive T cell transfer. In addition to the 50 oral presentations and >180 posters on these topics, a new SITC/iSBTc initiative to create evidence-based Cancer Immunotherapy Guidelines was announced. The SITC/iSBTc Biomarkers Taskforce announced the release of recommendations on immunotherapy biomarkers and a highly successful symposium on Immuno-Oncology Biomarkers that took place on the campus of the National Institutes of Health (NIH immediately prior to the Annual Meeting. At the Annual Meeting, the NIH took the opportunity to publicly announce the award of the U01 grant that will fund the Cancer Immunotherapy Trials Network (CITN. In summary, the Annual Meeting gathered clinicians and scientists from academia, industry, and regulatory agencies from around the globe to interact and exchange important scientific advances related to tumor immunobiology and cancer immunotherapy.

The reproducibility of organ position using active breathing control (ABC) during liver radiotherapy

International Nuclear Information System (INIS)

Dawson, Laura A.; Brock, Kristy K.; Kazanjian, Sahira; Fitch, Dwight; McGinn, Cornelius J.; Lawrence, Theodore S.; Haken, Randall K. ten; Balter, James

2001-01-01

Purpose: To evaluate the intrafraction and interfraction reproducibility of liver immobilization using active breathing control (ABC). Methods and Materials: Patients with unresectable intrahepatic tumors who could comfortably hold their breath for at least 20 s were treated with focal liver radiation using ABC for liver immobilization. Fluoroscopy was used to measure any potential motion during ABC breath holds. Preceding each radiotherapy fraction, with the patient setup in the nominal treatment position using ABC, orthogonal radiographs were taken using room-mounted diagnostic X-ray tubes and a digital imager. The radiographs were compared to reference images using a 2D alignment tool. The treatment table was moved to produce acceptable setup, and repeat orthogonal verification images were obtained. The positions of the diaphragm and the liver (assessed by localization of implanted radiopaque intra-arterial microcoils) relative to the skeleton were subsequently analyzed. The intrafraction reproducibility (from repeat radiographs obtained within the time period of one fraction before treatment) and interfraction reproducibility (from comparisons of the first radiograph for each treatment with a reference radiograph) of the diaphragm and the hepatic microcoil positions relative to the skeleton with repeat breath holds using ABC were then measured. Caudal-cranial (CC), anterior-posterior (AP), and medial-lateral (ML) reproducibility of the hepatic microcoils relative to the skeleton were also determined from three-dimensional alignment of repeat CT scans obtained in the treatment position. Results: A total of 262 fractions of radiation were delivered using ABC breath holds in 8 patients. No motion of the diaphragm or hepatic microcoils was observed on fluoroscopy during ABC breath holds. From analyses of 158 sets of positioning radiographs, the average intrafraction CC reproducibility (σ) of the diaphragm and hepatic microcoil position relative to the skeleton

Progress report on nuclear science and technology in China (Vol.3). Proceedings of academic annual meeting of China Nuclear Society in 2013, No.3--nuclear power sub-volume (Pt.2)

International Nuclear Information System (INIS)

2014-05-01

Progress report on nuclear science and technology in China (Vol. 3) includes 86 articles which are communicated on the third national academic annual meeting of China Nuclear Society. There are 10 books totally. This is the third one, the content is about nuclear power sub-volume (Pt.2)

Highlights of the XXI annual meeting of the Brazilian Society of Protozoology, the XXXII annual meeting on Basic Research in Chagas' disease & an international symposium on vesicle trafficking in parasitic Protozoa--7 to 9 November 2005, Caxambu, Minas Gerais, Brazil.

Science.gov (United States)

Shaw, Jeffrey; Schenkman, Sergio; Rodrigues, Mauricio Martins

2006-08-17

This report focuses on the 2005 Annual meeting held in Caxambu, Minas Gerais, Brazil that was convened and organized by the Brazilian Society of Protozoology http://www.sbpz.org.br/. This is an annual event and details of these meetings can be found on the Society's website. Within the space available it has been impossible to cover all the important and fascinating contributions and what is presented are our personal views of the meetings scientific highlights and new developments. The contents undoubtedly reflect each author's scientific interests and expertise. Fuller details of the round tables, seminars and posters can be consulted on line at http://www.sbpz.org.br/livroderesumos2005.php.

CO2 Emissions Generated by a Fall AGU Meeting

Science.gov (United States)

osborn, G.; Malowany, K. S.; Samolczyk, M. A.

2011-12-01

CO2 for the fall 2010 meeting. For comparison, 19 million kg is roughly equivalent to the annual CO2 emissions of the smallest Pacific island nations and to 1/1000 of the annual CO2 emissions of Tunisia; it is 5000 times greater than average annual global per capita CO2 emissions. Additional contributions to greenhouse warming arising from air travel to/from a meeting are made by the effects of water-vapor contrails, considered by Burkhardt and Karcher (2011) to be conceivably more significant than direct CO2 emissions. We make no value judgement regarding the balance between scientific progress and environmental costs consequent to AGU and other large scientific meetings that deal with greenhouse warming. We do perceive a hint of irony, however, in the pride that AGU takes in the ever-increasing numbers of meeting participants. Burkhardt, U. and Karcher, B., 2011, Nature Climate Change 1:54-58.

Annual meeting 1996 'Nondestructive material testing'. German, Austrian and Swiss nondestructive materials testing standards as mirrored by international standardization. Vol. 2. Posters

International Nuclear Information System (INIS)

1996-01-01

The volume contains 49 poster articles which were presented at the Annual Meeting of the German Society for Nondestructive Testing at Lindau on May 13-15, 1996. The main subjects were: Standardization of nondestructive testing, irradiation testing, ultrasonic testing and electromagnetic processes. 16 individual articles were included in the ENERGY databank. (MM) [de

25th annual meeting of the German Society of Neuroradiology. Abstracts

International Nuclear Information System (INIS)

Grau, H.C.

1990-01-01

The 62 abstracts are precising the individual papers read at the 25th annual meeting of the Germany Society of Neuroradiology, which dealt with the following subjects: The narrowed vertebral canal, congential and acquired spinal compression syndromes (8); neuroradiology of disturbances of perinatal development (7); new horizons in the diagnosis of degenerative and inflammatory disorders of the white matter (14); interventional neuroradiology (12); miscellaneous topics (21). (UHE) [de

Design and economic optimization of shell and tube heat exchangers using Artificial Bee Colony (ABC) algorithm

International Nuclear Information System (INIS)

Sencan Sahin, Arzu; Kilic, Bayram; Kilic, Ulas

2011-01-01

Highlights: → Artificial Bee Colony for shell and tube heat exchanger optimization is used. → The total cost is minimized by varying design variables. → This new approach can be applied for optimization of heat exchangers. - Abstract: In this study, a new shell and tube heat exchanger optimization design approach is developed. Artificial Bee Colony (ABC) has been applied to minimize the total cost of the equipment including capital investment and the sum of discounted annual energy expenditures related to pumping of shell and tube heat exchanger by varying various design variables such as tube length, tube outer diameter, pitch size, baffle spacing, etc. Finally, the results are compared to those obtained by literature approaches. The obtained results indicate that Artificial Bee Colony (ABC) algorithm can be successfully applied for optimal design of shell and tube heat exchangers.

Design and economic optimization of shell and tube heat exchangers using Artificial Bee Colony (ABC) algorithm

Energy Technology Data Exchange (ETDEWEB)

Sencan Sahin, Arzu, E-mail: sencan@tef.sdu.edu.tr [Department of Mechanical Education, Technical Education Faculty, Sueleyman Demirel University, 32260 Isparta (Turkey); Kilic, Bayram, E-mail: bayramkilic@hotmail.com [Bucak Emin Guelmez Vocational School, Mehmet Akif Ersoy University, Bucak (Turkey); Kilic, Ulas, E-mail: ulaskilic@mehmetakif.edu.tr [Bucak Emin Guelmez Vocational School, Mehmet Akif Ersoy University, Bucak (Turkey)

2011-10-15

Highlights: {yields} Artificial Bee Colony for shell and tube heat exchanger optimization is used. {yields} The total cost is minimized by varying design variables. {yields} This new approach can be applied for optimization of heat exchangers. - Abstract: In this study, a new shell and tube heat exchanger optimization design approach is developed. Artificial Bee Colony (ABC) has been applied to minimize the total cost of the equipment including capital investment and the sum of discounted annual energy expenditures related to pumping of shell and tube heat exchanger by varying various design variables such as tube length, tube outer diameter, pitch size, baffle spacing, etc. Finally, the results are compared to those obtained by literature approaches. The obtained results indicate that Artificial Bee Colony (ABC) algorithm can be successfully applied for optimal design of shell and tube heat exchangers.

Latest discoveries and trends in translational cancer research: highlights of the 2008 Annual Meeting of the American Association for Cancer Research.

Science.gov (United States)

Cho, William C S

2008-08-01

The Annual Meeting of the American Association for Cancer Research (AACR) is the world's largest and most comprehensive gathering of cancer researchers. At the 2008 AACR Annual Meeting, innovative research approaches, novel technologies, potentially life-saving therapies in the pipeline, late-breaking clinical trial findings, and new approaches to cancer prevention were presented by top scientists. Reflecting the global state of cancer research with an eye toward future trends, several areas of great science and discovery in the cancer field were shared in this report, which include cancer biomarkers, the role of microRNAs in cancer research, cancer stem cells, tumor microenvironment, targeted therapy, and cancer prevention. This article presents an overview of hot topics discussed at the 2008 AACR Annual Meeting and recapitulates some scientific sessions geared toward new technologies, recent progress, and current challenges reported by cancer researchers. For those who did not attend the meeting, this report may serve as a highlight of this important international cancer research meeting.

Annual meeting of the Advanced Light Source Users' Association

International Nuclear Information System (INIS)

1994-03-01

This report contains discussions on: Welcome to the annual meeting of the ALS User's Association; overview of the ALS; the ALS into the 21st century; report from the DOE; scientific program at the ALS; plans for industrial use of the ALS; progress in beamline commissioning and overview of new projects; ALS user program; the fluorescent x-ray microprobe beamline at the ALS; the early days of x-ray optics; high-resolution soft x-ray spectroscopy; soft x-ray emission spectroscopy; x-ray dichroism; and application of VUV undulator beamline to chemical dynamics at the ALS

The ABC of ABC : An analysis of attribute-based credentials in the light of data protection, privacy and identity.

NARCIS (Netherlands)

Korenhof, P.E.I.; Koning, Merel; Alpár, Gergely; Hoepman, J.H.; Padullés, Joan Balcells; i Martínez, Agustí Cerrillo; Poch, Miquel Peguera; López, Ismael Peña; de Moner, María José Pifarré; Solana, Mònica Vilasau

2014-01-01

Our networked society increasingly needs secure identity sys- tems. The Attribute-based credential (ABC) technology is designed to be privacy-friendlier than contemporary authentication methods, which often suffer from information leakage. So far, however, some of the wider implications of ABC have

76 FR 39074 - Mid-Atlantic Fishery Management Council; Public Meetings

Science.gov (United States)

2011-07-05

... Bluefish, Summer Flounder, Scup, and Black Sea Bass Monitoring Committees will hold public meetings. DATES... Bluefish, Summer Flounder, Scup, and Black Sea Bass Monitoring Committees will meet on Friday, July 29... and specify overfishing level and acceptable biological catch (ABC) for bluefish, summer flounder...

Identification of five partial ABC genes in the liver of the Antarctic fish Trematomus bernacchii and sensitivity of ABCB1 and ABCC2 to Cd exposure

Energy Technology Data Exchange (ETDEWEB)

Zucchi, Sara, E-mail: zucchi2@unisi.i [Department of Environmental Sciences ' G. Sarfatti' , University of Siena, Via Mattioli 4, 53100 Siena (Italy); Corsi, Ilaria [Department of Environmental Sciences ' G. Sarfatti' , University of Siena, Via Mattioli 4, 53100 Siena (Italy); Luckenbach, Till [UFZ - Helmholtz Centre for Environmental Research, Permoserstr. 15, D-04318 Leipzig (Germany); Bard, Shannon Mala [Environmental Programmes, Dalhousie University, 1355 Oxford Street, Life Science Centre, Room 820, Halifax, Nova Scotia, Canada B3H 4J1 (Canada); Regoli, Francesco [Department of Biochemistry, Biology and Genetics, Polytechnic University of Marches, Ancona (Italy); Focardi, Silvano [Department of Environmental Sciences ' G. Sarfatti' , University of Siena, Via Mattioli 4, 53100 Siena (Italy)

2010-08-15

Several ABC transporters have been characterized from many aquatic organisms, but no information is yet available for Antarctic fish. The aim of this work was to identify the expression of genes for ABC proteins in Trematomus bernacchii, a bioindicator species of the Southern Ocean. Partial cDNA sequences of ABCB1, ABCC1, ABCC2, ABCC4 and ABCC9 were cloned from liver. Using RACE technology, 3.5 and 2.2 kb contigs were obtained for ABCB1 and ABCC2. Considering the elevated natural bioavailability of cadmium at Terra Nova Bay, responsiveness of ABCB1 and ABCC2 to this element was investigated under laboratory conditions. ABCB1 and ABCC2 mRNA levels were approximately four-fold higher in Cd-exposed fish compared to the controls. Induction of ABCB1 protein was also found by western blot. This study provides the first identification of five ABC genes in the liver of an Antarctic key species, some of which may be involved in cellular detoxification. - The presence of five partial sequences showing homology with ABC transporters and the sensitivity of ABCB1 and ABCC2 toward cadmium were determined in the liver of T. bernacchii.

The AbcA Transporter of Staphylococcus aureus Affects Cell Autolysis

Science.gov (United States)

Schrader-Fischer, Gesine; Berger-Bächi, Brigitte

2001-01-01

Increased production of penicillin-binding protein PBP 4 is known to increase peptidoglycan cross-linking and contributes to methicillin resistance in Staphylococcus aureus. The pbp4 gene shares a 400-nucleotide intercistronic region with the divergently transcribed abcA gene, encoding an ATP-binding cassette transporter of unknown function. Our study revealed that methicillin stimulated abcA transcription but had no effects on pbp4 transcription. Analysis of abcA expression in mutants defective for global regulators showed that abcA is under the control of agr. Insertional inactivation of abcA by an erythromycin resistance determinant did not influence pbp4 transcription, nor did it alter resistance to methicillin and other cell wall-directed antibiotics. However, abcA mutants showed spontaneous partial lysis on plates containing subinhibitory concentrations of methicillin due to increased spontaneous autolysis. Since the autolytic zymograms of cell extracts were identical in mutants and parental strains, we postulate an indirect role of AbcA in control of autolytic activities and in protection of the cells against methicillin. PMID:11158733

Trends in twitter use by physicians at the american society of clinical oncology annual meeting, 2010 and 2011.

Science.gov (United States)

Chaudhry, Aafia; Glodé, L Michael; Gillman, Matt; Miller, Robert S

2012-05-01

Social media channels such as Twitter are gaining increasing acceptance as mechanisms for instantaneous scientific dialogue. Professional medical societies such as ASCO are using social media to expand the reach of scientific communications at and around their scientific meetings. This article examines the how Twitter use by oncologists expanded at the ASCO Annual Meetings from 2010 to 2011. In both years, tweets that were specifically generated by physicians and that incorporated the official meeting hashtag were harvested from the public domain, and a discourse analysis was performed by three independent raters. Follow-up surveys were conducted to assess physician attitudes toward Twitter and its potential role in clinical practice. A combined total of 12,644 tweets were analyzed for 2010 and 2011. Although the number of physicians authoring tweets was small (14 in 2010, 34 in 2011), this group generated nearly 29% of the total meeting dialogue examined in this analysis in 2010 and 23% in 2011. Physicians used Twitter for reporting clinical news from scientific sessions, for discussions of treatment issues, for promotion, and to provide social commentary. The tangible impact of Twitter discussions on clinical practice remains unclear. Despite the 140-character limit, Twitter was successfully used by physicians at the 2010 and 2011 ASCO Annual Meetings to engage in clinical discussions, whether or not an author was on site as a live attendee. Twitter usage grew significantly from 2010 to 2011. Professional societies should monitor these phenomena to enhance annual meeting attendee user experience.

Annual meeting on nuclear technology 2005. Proceedings

International Nuclear Information System (INIS)

2005-03-01

The proceedings of the annual meeting on nuclear technology 2005 covers the following issues: (1) reactor physics and methods of calculation: design and transients; method development and validation; (2): thermodynamics and fluid dynamics: analytical thermohydraulics for existing reactors; experiments and operational behavior; analytical methods for innovative reactors; (3) Safety of nuclear installations - methods, analysis, results: special problems; PSA and in-vessel phenomena; ex-vessel phenomena; (4) front end and back end of the fuel cycle, radioactive waste, storage: intermediate storage of fuel elements, waste treatment, (5) fuel elements and core components: fuel elements, new methods in the interpretation, manufacturing and service; (6) operation of nuclear installations: experience with the operation of NPPs; management systems, digital instrumentation and control of NPPs revision management; (7) decommissioning of nuclear installations: concepts and strategies for decommissioning and dismantling; experiences with decommissioning projects; (8) fusion technology: fusion facilities; materials and test facility; cryo technique and simulations; (9) research reactors: building new and backfitting of existing research reactors; current development; dismantling of research reactors; (10) advanced reactor concepts, energy systems, energy economics; (11) communication with the public; (12) component materials, fabrication and service behavior: degradation effects of component materials; component behavior; (13): radiation protection: PSA and in-vessel phenomena, ex-vessel phenomena.

Sensitive and specific fluorescent probes for functional analysis of the three major types of mammalian ABC transporters.

Science.gov (United States)

Lebedeva, Irina V; Pande, Praveen; Patton, Wayne F

2011-01-01

An underlying mechanism for multi drug resistance (MDR) is up-regulation of the transmembrane ATP-binding cassette (ABC) transporter proteins. ABC transporters also determine the general fate and effect of pharmaceutical agents in the body. The three major types of ABC transporters are MDR1 (P-gp, P-glycoprotein, ABCB1), MRP1/2 (ABCC1/2) and BCRP/MXR (ABCG2) proteins. Flow cytometry (FCM) allows determination of the functional expression levels of ABC transporters in live cells, but most dyes used as indicators (rhodamine 123, DiOC(2)(3), calcein-AM) have limited applicability as they do not detect all three major types of ABC transporters. Dyes with broad coverage (such as doxorubicin, daunorubicin and mitoxantrone) lack sensitivity due to overall dimness and thus may yield a significant percentage of false negative results. We describe two novel fluorescent probes that are substrates for all three common types of ABC transporters and can serve as indicators of MDR in flow cytometry assays using live cells. The probes exhibit fast internalization, favorable uptake/efflux kinetics and high sensitivity of MDR detection, as established by multidrug resistance activity factor (MAF) values and Kolmogorov-Smirnov statistical analysis. Used in combination with general or specific inhibitors of ABC transporters, both dyes readily identify functional efflux and are capable of detecting small levels of efflux as well as defining the type of multidrug resistance. The assay can be applied to the screening of putative modulators of ABC transporters, facilitating rapid, reproducible, specific and relatively simple functional detection of ABC transporter activity, and ready implementation on widely available instruments.

Enchanted Clays: 44th Annual Meeting of the Clay Minerals Society (June 2007)

Energy Technology Data Exchange (ETDEWEB)

Randall T. Cygan

2007-06-01

“Enchanted Clays: 44th Annual Meeting of the Clay Minerals Society” was held in early June 2007 in beautiful and historic Santa Fe, New Mexico, USA. Santa Fe provided an idyllic location in the southwestern United States for the attendees to enjoy technical and social sessions while soaking up the diverse culture and wonderful climate of New Mexico—The Land of Enchantment. The meeting included a large and varied group of scientists, sharing knowledge and ideas, benefitting from technical interactions, and enjoying the wonderful historic and enchanted environs of Santa Fe. Including significant number of international scientists, the meeting was attended by approximately two hundred participants. The meeting included three days of technical sessions (oral and poster presentations), three days of field trips to clay and geological sites of northern New Mexico, and a full day workshop on the stabilization of carbon by clays. Details can be found at the meeting web site: www.sandia.gov/clay.

Novel understanding of ABC transporters ABCB1/MDR/P-glycoprotein, ABCC2/MRP2, and ABCG2/BCRP in colorectal pathophysiology

DEFF Research Database (Denmark)

Andersen, Vibeke; Svenningsen, Katrine; Knudsen, Lina Almind

2015-01-01

transporter proteins, inflammatory bowel disease, ulcerative, colitis, Crohns disease, colorectal cancer, colitis, intestinal inflammation, intestinal carcinogenesis, ABCB1/P-glycoprotein (P-gp/CD243/MDR1), ABCC2/multidrug resistance protein 2 (MRP2) and ABCG2/breast cancer resistance protein (BCRP), Abcb1....../Mdr1a, abcc2/Mrp2, abcg2/Bcrp, knock-out mice, tight junction, membrane lipid function. RESULTS: Recently, human studies reported that changes in the levels of ABC transporters were early events in the adenoma-carcinoma sequence leading to CRC. A link between ABCB1, high fat diet and gut microbes...

Analysis of ABC (D) stratification for screening patients with gastric cancer.

Science.gov (United States)

Kudo, Tomohiro; Kakizaki, Satoru; Sohara, Naondo; Onozato, Yasuhiro; Okamura, Shinichi; Inui, Yoshikatsu; Mori, Masatomo

2011-11-21

To evaluate the value of ABC (D) stratification [combination of serum pepsinogen and Helicobacter pylori (H. pylori) antibody] of patients with gastric cancer. Ninety-five consecutive patients with gastric cancer were enrolled into the study. The serum pepsinogen I (PG I)/pepsinogen II (PG II) and H. pylori antibody levels were measured. Patients were classified into five groups of ABC (D) stratification according to their serological status. Endoscopic findings of atrophic gastritis and histological differentiation were also analyzed in relation to the ABC (D) stratification. The mean patient age was (67.9 ± 8.9) years. Three patients (3.2%) were classified into group A, 7 patients (7.4%) into group A', 27 patients (28.4%) into group B, 54 patients (56.8%) into group C, and 4 patients (4.2%) into group D, respectively. There were only three cases in group A when the patients taking acid proton pump inhibitors and those who had undergone eradication therapy for H. pylori (group A') were excluded. These three cases had mucosal atrophy in the grey zone according to the diagnostic manual of ABC (D) stratification. Histologically, the mean age of the patients with well differentiated adenocarcinoma was significantly higher than that of the patients with poorly differentiated adenocarcinoma (P ABC (D) stratification is a good method for screening patients with gastric cancers. Endoscopy is needed for grey zone cases to check the extent of mucosal atrophy.

Quantitative Psychology : the 82nd Annual Meeting of the Psychometric Society

CERN Document Server

Culpepper, Steven; Janssen, Rianne; González, Jorge; Molenaar, Dylan

2018-01-01

This proceedings book highlights the latest research and developments in psychometrics and statistics. Featuring contributions presented at the 82nd Annual Meeting of the Psychometric Society (IMPS), organized by the University of Zurich and held in Zurich, Switzerland from July 17 to 21, 2017, its 34 chapters address a diverse range of psychometric topics including item response theory, factor analysis, causal inference, Bayesian statistics, test equating, cognitive diagnostic models and multistage adaptive testing. The IMPS is one of the largest international meetings on quantitative measurement in psychology, education and the social sciences, attracting over 500 participants and 250 paper presentations from around the world every year. This book gathers the contributions of selected presenters, which were subsequently expanded and peer-reviewed.

Transmembrane Domain Single-Nucleotide Polymorphisms Impair Expression and Transport Activity of ABC Transporter ABCG2

NARCIS (Netherlands)

Sjostedt, N.; Heuvel, J.J.M.W. van den; Koenderink, J.B.; Kidron, H.

2017-01-01

PURPOSE: To study the function and expression of nine naturally occurring single-nucleotide polymorphisms (G406R, F431L, S441N, P480L, F489L, M515R, L525R, A528T and T542A) that are predicted to reside in the transmembrane regions of the ABC transporter ABCG2. METHODS: The transport activity of the

Transcriptional expression analysis of ABC efflux transporters and xenobiotic-metabolizing enzymes in the Chinese rare minnow.

Science.gov (United States)

Yuan, Lilai; Lv, Biping; Zha, Jinmiao; Wang, Zijian

2014-05-01

In the present study, the cDNA fragments of five ABC transporter genes (ABCB1, ABCB11, ABCC1, ABCC2, and ABCG2) in the rare minnow were cloned, and their tissue-specific expression patterns were evaluated across eight rare minnow tissues (liver, gill, intestine, kidney, spleen, brain, skin, and muscle). Furthermore, the transcriptional effects on these ABC transporter genes and five xenobiotic-metabolizing enzyme genes (CYP1A, GSTm, GSTp1, GCLC, and UGT1a) were determined in the rare minnow liver after 12 days of pyrene exposure. Basal expression analysis showed that the tissues with high expression of the ABC transporters included the liver, kidney, and intestine. Moreover, the most highly expressed of the ABC genes were ABCB1 and ABCC2 in all eight of the tissues tested. The ABCB11 gene was almost exclusively expressed in the liver of the rare minnow, whereas ABCC1 and ABCG2 showed weak expression in all eight tissues compared to ABCB1 and ABCC2. Our results provide the first thorough examination of the expression patterns of toxicologically relevant ABC transporters in the rare minnow and serve as a necessary basis for further studies of these ABC transporters in fish. Furthermore, synergistic up-regulation of CYP1A, GSTp1, GCLC, UGT1a, and ABCC2 was observed in the rare minnow liver following pyrene exposure, while GSTm, ABCB1, ABCB11, ABCC1, and ABCG2 were not significantly affected (p ABC transporters by pyrene suggests a possible involvement and cooperation of these genes in the detoxification process in rare minnows. Copyright © 2014 Elsevier B.V. All rights reserved.

Prelude to Professional Identity and Organization: American Public School Curriculum Workers and Their Annual Meetings, 1927-1929.

Science.gov (United States)

Davis, O. L., Jr.

2002-01-01

Describes principal participants and agenda at informal annual meetings of public-school curriculum works in late 1920s; meetings eventually led to the creation of a professional association for curriculum practitioners and researches: The Society for Curriculum Study, later to become the Association for Supervision and Curriculum Development.…

Diversity and evolution of ABC proteins in mycorrhiza-forming fungi.

Science.gov (United States)

Kovalchuk, Andriy; Kohler, Annegret; Martin, Francis; Asiegbu, Fred O

2015-12-28

Transporter proteins are predicted to have an important role in the mycorrhizal symbiosis, due to the fact that this type of an interaction between plants and fungi requires a continuous nutrient and signalling exchange. ABC transporters are one of the large groups of transporter proteins found both in plants and in fungi. The crucial role of plant ABC transporters in the formation of the mycorrhizal symbiosis has been demonstrated recently. Some of the fungal ABC transporter-encoding genes are also induced during the mycorrhiza formation. However, no experimental evidences of the direct involvement of fungal ABC transporters in this process are available so far. To facilitate the identification of fungal ABC proteins with a potential role in the establishment of the mycorrhizal symbiosis, we have performed an inventory of the ABC protein-encoding genes in the genomes of 25 species of mycorrhiza-forming fungi. We have identified, manually annotated and curated more than 1300 gene models of putative ABC protein-encoding genes. Out of those, more than 1000 models are predicted to encode functional proteins, whereas about 300 models represent gene fragments or putative pseudogenes. We have also performed the phylogenetic analysis of the identified sequences. The sets of ABC proteins in the mycorrhiza-forming species were compared to the related saprotrophic or plant-pathogenic fungal species. Our results demonstrate the high diversity of ABC genes in the genomes of mycorrhiza-forming fungi. Via comparison of transcriptomics data from different species, we have identified candidate groups of ABC transporters that might have a role in the process of the mycorrhiza formation. Results of our inventory will facilitate the identification of fungal transporters with a role in the mycorrhiza formation. We also provide the first data on ABC protein-coding genes for the phylum Glomeromycota and for orders Pezizales, Atheliales, Cantharellales and Sebacinales, contributing to

Polymorphism in ABC transporter genes of Dirofilaria immitis

Directory of Open Access Journals (Sweden)

Thangadurai Mani

2017-08-01

Full Text Available Dirofilaria immitis, a filarial nematode, causes dirofilariasis in dogs, cats and occasionally in humans. Prevention of the disease has been mainly by monthly use of the macrocyclic lactone (ML endectocides during the mosquito transmission season. Recently, ML resistance has been confirmed in D. immitis and therefore, there is a need to find new classes of anthelmintics. One of the mechanisms associated with ML resistance in nematodes has been the possible role of ATP binding cassette (ABC transporters in reducing drug concentrations at receptor sites. ABC transporters, mainly from sub-families B, C and G, may contribute to multidrug resistance (MDR by active efflux of drugs out of the cell. Gene products of ABC transporters may thus serve as the targets for agents that may modulate susceptibility to drugs, by inhibiting drug transport. ABC transporters are believed to be involved in a variety of physiological functions critical to the parasite, such as sterol transport, and therefore may also serve as the target for drugs that can act as anthelmintics on their own. Knowledge of polymorphism in these ABC transporter genes in nematode parasites could provide useful information for the process of drug design. We have identified 15 ABC transporter genes from sub-families A, B, C and G, in D. immitis, by comparative genomic approaches and analyzed them for polymorphism. Whole genome sequencing data from four ML susceptible (SUS and four loss of efficacy (LOE pooled populations were used for single nucleotide polymorphism (SNP genotyping. Out of 231 SNPs identified in those 15 ABC transporter genes, 89 and 75 of them were specific to the SUS or LOE populations, respectively. A few of the SNPs identified may affect gene expression, protein function, substrate specificity or resistance development and may be useful for transporter inhibitor/anthelmintic drug design, or in order to anticipate resistance development. Keywords: Dirofilaria immitis

Sustained Delivery of Chondroitinase ABC from Hydrogel System

Directory of Open Access Journals (Sweden)

Filippo Rossi

2012-03-01

Full Text Available In the injured spinal cord, chondroitin sulfate proteoglycans (CSPGs are the principal responsible of axon growth inhibition and they contribute to regenerative failure, promoting glial scar formation. Chondroitinase ABC (chABC is known for being able to digest proteoglycans, thus degrading glial scar and favoring axonal regrowth. However, its classic administration is invasive, infection-prone and clinically problematic. An agarose-carbomer (AC1 hydrogel, already used in SCI repair strategies, was here investigated as a delivery system capable of an effective chABC administration: the material ability to include chABC within its pores and the possibility to be injected into the target tissue were firstly proved. Subsequently, release kinetic and the maintenance of enzymatic activity were positively assessed: AC1 hydrogel was thus confirmed to be a feasible tool for chABC delivery and a promising device for spinal cord injury topic repair strategies.

Generics, Supergenerics and Patent Strategies--SMi's 13th Annual Meeting.

Science.gov (United States)

Edwards, Catherine

2010-07-01

SMi's 13th Annual Meeting on Generics, Supergenerics and Patent Strategies, held in London, included topics covering new trends in the generics field, the difficulties faced by companies in entering the generics market and recent developments in IP. This conference report highlights selected presentations on generics in India, protecting pharmaceutical products in China, changes in generics law and litigation in the US and Europe, challenges for market selection and entry for generics companies, the influence of changes in the healthcare market on the generics industry, supergenerics, and biosimilars.

78 FR 47829 - Notice of Open Meetings To Prepare 2013 Annual Report to Congress

Science.gov (United States)

2013-08-06

... ``regarding the national security implications and impact of the bilateral trade and economic relationship.... security interests, including a military and security year in review, cyber activities and maritime... U.S.-CHINA ECONOMIC AND SECURITY REVIEW COMMISSION Notice of Open Meetings To Prepare 2013 Annual...

24 Annual meeting of the Spanish Nuclear Society: Valladolid 14-16 October 1998: program and synopsis of lectures

International Nuclear Information System (INIS)

1998-01-01

The technical sessions of XXIV annual meeting of the Spanish Nuclear Society were: 1) Fusion 2) Engineering: calculation and simulation. 3) Economical, legal and social aspect 4) Plant life extension 5) Operating experiences, refueling and operation support 6) Probabilistic safety 7) Radiological protection 8) Waste Management 9) Maintenance 10) Nuclear Safety R and D 11) Environmental aspects 12) Fuel 13) Quality

The 23rd Annual Meeting of the European Tissue Repair Society (ETRS) in Reims, France

NARCIS (Netherlands)

Hoff, J.W. Von den; Agren, M.S.; Coulomb, B.; Eming, S.A.; Lataillade, J.J.

2014-01-01

The 23rd Annual Meeting of the European Tissue Repair Society, Reims, France, October 23 to 25, 2013 focused on tissue repair and regenerative medicine covering topics such as stem cells, biomaterials, tissue engineering, and burns.

Genome-wide identification, characterization and phylogenetic analysis of 50 catfish ATP-binding cassette (ABC) transporter genes.

Science.gov (United States)

Liu, Shikai; Li, Qi; Liu, Zhanjiang

2013-01-01

Although a large set of full-length transcripts was recently assembled in catfish, annotation of large gene families, especially those with duplications, is still a great challenge. Most often, complexities in annotation cause mis-identification and thereby much confusion in the scientific literature. As such, detailed phylogenetic analysis and/or orthology analysis are required for annotation of genes involved in gene families. The ATP-binding cassette (ABC) transporter gene superfamily is a large gene family that encodes membrane proteins that transport a diverse set of substrates across membranes, playing important roles in protecting organisms from diverse environment. In this work, we identified a set of 50 ABC transporters in catfish genome. Phylogenetic analysis allowed their identification and annotation into seven subfamilies, including 9 ABCA genes, 12 ABCB genes, 12 ABCC genes, 5 ABCD genes, 2 ABCE genes, 4 ABCF genes and 6 ABCG genes. Most ABC transporters are conserved among vertebrates, though cases of recent gene duplications and gene losses do exist. Gene duplications in catfish were found for ABCA1, ABCB3, ABCB6, ABCC5, ABCD3, ABCE1, ABCF2 and ABCG2. The whole set of catfish ABC transporters provide the essential genomic resources for future biochemical, toxicological and physiological studies of ABC drug efflux transporters. The establishment of orthologies should allow functional inferences with the information from model species, though the function of lineage-specific genes can be distinct because of specific living environment with different selection pressure.

An ABC analysis for power generation project

Directory of Open Access Journals (Sweden)

Batool Hasani

2013-07-01

Full Text Available One of the primary concerns on performance measurement is to know how much a particular project cost. However, using traditional method on project-based products often leads to inappropriate results. In this paper, we re-examine this issue by comparing the cost of a power station construction project using ABC versus traditional method. The results of survey show that ABC method is capable of providing better estimates for overhead costs compared with traditional method. In other words, ABC method helps reduce some of the unnecessary overhead cost items and increase on some other cost components. This helps increase the relative efficiency of the system by reducing total cost of project.

Progress report on nuclear science and technology in China (Vol.2). Proceedings of academic annual meeting of China Nuclear Society in 2011, No.10--nuclear technology economy and management modernization sub-volume

International Nuclear Information System (INIS)

2012-10-01

Progress report on nuclear science and technology in China (Vol. 2) includes 698 articles which are communicated on the second national academic annual meeting of China Nuclear Society. There are 10 books totally. This is the tenth one, the content is about nuclear technology economy and management modernization

Progress report on nuclear science and technology in China (Vol.2). Proceedings of academic annual meeting of China Nuclear Society in 2011, No.7--Nuclear electronics and nuclear detection technology sub-volume

International Nuclear Information System (INIS)

2012-10-01

Progress report on nuclear science and technology in China (Vol. 2) includes 698 articles which are communicated on the second national academic annual meeting of China Nuclear Society. There are 10 books totally. This is the seventh one, the content is about Nuclear electronics and nuclear detection technology

Alcohol and Trauma: A Summary of the Satellite Symposium at the 30th Annual Meeting of the Shock Society

Science.gov (United States)

Bird, Melanie D.; Choudhry, Mashkoor A.; Molina, Patricia E.; Kovacs, Elizabeth J.

2009-01-01

This article highlights the research presented at the Alcohol and Trauma Satellite Symposium at the 30th Annual Shock Society Annual Meeting. The satellite meeting was held on June 8th and 9th in Baltimore, MD. Its purpose was to discuss recent findings in the areas of alcohol and injury, including the effect of alcohol use on patients in the trauma unit of hospitals. The meeting consisted of three sessions, with plenary talks by invited speakers, short talks from selected abstracts, and a poster session. Participants presented data on the effects of alcohol on organ function, healing, and immune processes after a variety of injuries including burn, hemorrhagic shock, sepsis, and ischemia-reperfusion. PMID:19393863

[Fortieth Annual] Meeting of the Technical Working Group on Fast Reactors (TWG-FR). Working Material

International Nuclear Information System (INIS)

2008-01-01

The objectives of the meeting were to: - Exchange information on the national programmes on Fast Reactors (FR) and Accelerator Driven Systems (ADS); - Review the progress since the 39th TWG-FR Annual Meeting, including the status of the actions; - Consider meeting arrangements for 2007, 2008 and 2009; - Review the Agency’s ongoing information exchange and co-ordinated research activities in the technical fields relevant to the TWG-FR (FRs and ADS), as well as coordination of the TWG-FR’s activities with other organizations; - Discuss future joint activities in view of the Agency’s Programme and Budget Cycle 2008–2009 (and beyond)

Remedial Action Programs annual meeting: Proceedings

International Nuclear Information System (INIS)

1988-01-01

Within the DOE's Office of Nuclear Energy, the Office of Remedial Action and Waste Technology manages a number of programs whose purposes are to complete remedial actions at DOE facilities and sites located throughout the United States. These programs include the Surplus Facilities Management Program, the Formerly Utilized Sites Remedial Action Program, the Uranium Mill Tailings remedial Action Program and the West Valley Demonstration Project. The programs involve the decontamination and decommissioning of radioactively-contaminated structures and equipment, the disposal of uranium mill tailings, and the cleanup or restoration of soils and ground water that have been contaminated with radioactive hazardous substances. Each year the DOE and DOE-contractor staff who conduct these programs meet to exchange information and experience in common technical areas. This year's meeting was hosted by the Surplus Facilities Management Program and was held near DOE Headquarters, in Gaithersburg, Maryland. This volume of proceedings provides the record for the meeting. The proceedings consist of abstracts for each presentation made at the meeting, and the visual aids (if any) used by the speakers. The material is organized in the following pages according to the five different sessions at the meeting: Session 1: Environmental Compliance--Policy; Session 2: Environmental Compliance--Practice; Session 3: Reports from working groups; Session 4: DandD Technology; and Session 5: Remedial Action Technology. The agenda for the meeting and the list of meeting registrants are provided in Appendix A and B, respectively. Individual papers are processed separately for the data base

Progress report on nuclear science and technology in China (Vol.2). Proceedings of academic annual meeting of China Nuclear Society in 2011, No.7--pulse power technology and its application sub-volume

International Nuclear Information System (INIS)

2012-10-01

Progress report on nuclear science and technology in China (Vol. 2) includes 698 articles which are communicated on the second national academic annual meeting of China Nuclear Society. There are 10 books totally. This is the seventh one, the content is about Nuclear electronics and pulse power technology and its application

A Survey of the ATP-Binding Cassette (ABC) Gene Superfamily in the Salmon Louse (Lepeophtheirus salmonis).

Science.gov (United States)

Carmona-Antoñanzas, Greta; Carmichael, Stephen N; Heumann, Jan; Taggart, John B; Gharbi, Karim; Bron, James E; Bekaert, Michaël; Sturm, Armin

2015-01-01

Salmon lice, Lepeophtheirus salmonis (Krøyer, 1837), are fish ectoparasites causing significant economic damage in the mariculture of Atlantic salmon, Salmo salar Linnaeus, 1758. The control of L. salmonis at fish farms relies to a large extent on treatment with anti-parasitic drugs. A problem related to chemical control is the potential for development of resistance, which in L. salmonis is documented for a number of drug classes including organophosphates, pyrethroids and avermectins. The ATP-binding cassette (ABC) gene superfamily is found in all biota and includes a range of drug efflux transporters that can confer drug resistance to cancers and pathogens. Furthermore, some ABC transporters are recognised to be involved in conferral of insecticide resistance. While a number of studies have investigated ABC transporters in L. salmonis, no systematic analysis of the ABC gene family exists for this species. This study presents a genome-wide survey of ABC genes in L. salmonis for which, ABC superfamily members were identified through homology searching of the L. salmonis genome. In addition, ABC proteins were identified in a reference transcriptome of the parasite generated by high-throughput RNA sequencing (RNA-seq) of a multi-stage RNA library. Searches of both genome and transcriptome allowed the identification of a total of 33 genes / transcripts coding for ABC proteins, of which 3 were represented only in the genome and 4 only in the transcriptome. Eighteen sequences were assigned to ABC subfamilies known to contain drug transporters, i.e. subfamilies B (4 sequences), C (11) and G (2). The results suggest that the ABC gene family of L. salmonis possesses fewer members than recorded for other arthropods. The present survey of the L. salmonis ABC gene superfamily will provide the basis for further research into potential roles of ABC transporters in the toxicity of salmon delousing agents and as potential mechanisms of drug resistance.

Proceedings of the 24th Day of Scientific lectures and 20th Annual Meeting of the National Society of Black Physicists

Energy Technology Data Exchange (ETDEWEB)

Jackson, K.H; Carwell, H.V.

1999-11-29

The National Society of Black Physicists will hold its Twentieth annual meeting and its XXIIII Day of Scientific Lectures at Lawrence Berkeley National Laboratory on March 27th - 30th, 1997. The meeting provides a major opportunity for African American physicists and students to present their current research and discuss issues germane to the constituency. It is therefore crucial to have the broadest cross-section of the membership at each meeting. The Lawrence Berkeley National Laboratory was chosen as the site of the 20th annual meeting because of its historical significance to Physics (being one of the first national laboratories in the United States) and the laboratories continuing support of the goals and objectives of the society.

XXII annual meeting of the Spanish Nuclear Society, Santander 22-26 October 1996: program and synopsis of lectures

International Nuclear Information System (INIS)

1996-01-01

The technical sessions of XXII annual meeting of the Spanish Nuclear Society were: 1) Fusion 2) Engineering: calculation and simulation. 3) Economical, legal and social aspect 4) Plant life extension 5) Operating experiences, refueling and operation support 9)Probabilistic safety 7) radiological protection 8) Waste management 9) Maintenance 10) Advanced plants 11) Steam generators 12) Nuclear Safety. R and D 13) Environmental aspects 14) Fuel 15) Quality

New technology and clinical applications of nanomedicine: highlights of the second annual meeting of the American Academy of Nanomedicine (Part I).

Science.gov (United States)

Wei, Chiming; Lyubchenko, Yuri L; Ghandehari, Hamid; Hanes, Justin; Stebe, Kathleen J; Mao, Hai-Quan; Haynie, Donald T; Tomalia, Donald A; Foldvari, Marianna; Monteiro-Riviere, Nancy; Simeonova, Petia; Nie, Shuming; Mori, Hidezo; Gilbert, Susan P; Needham, David

2006-12-01

The Second Annual Meeting of the American Academy of Nanomedicine (AANM) was held at the National Academy of Science Building in Washington, DC, September 9-10, 2006. The program included two Nobel Prize Laureate Lectures, two Keynote Lectures, and 123 invited outstanding State-in-Art lectures presenting in 23 special concurrent symposia. In addition, there were 22 poster presentations in the meeting addressing different areas in nanomedicine research. All of the presenters at the meeting are outstanding investigators and researchers in the field. The Second Annual Meeting of the AANM was a great success. The meeting provides investigators from different world areas a forum and an opportunity for discussion. We believe that nanomedicine research will develop rapidly in the future. The AANM invites basic and clinical researchers from the world to join this exciting research.

abc: An Extensible AspectJ Compiler

DEFF Research Database (Denmark)

Avgustinov, Pavel; Christensen, Aske Simon; Hendren, Laurie J.

2006-01-01

checking and code generation, as well as data flow and control flow analyses. The AspectBench Compiler (abc) is an implementation of such a workbench. The base version of abc implements the full AspectJ language. Its front end is built using the Polyglot framework, as a modular extension of the Java...... language. The use of Polyglot gives flexibility of syntax and type checking. The back end is built using the Soot framework, to give modular code generation and analyses. In this paper, we outline the design of abc, focusing mostly on how the design supports extensibility. We then provide a general...

2007 annual meeting on nuclear technology. Report; Jahrestagung Kerntechnik 2007. Tagungsbericht

Energy Technology Data Exchange (ETDEWEB)

Anon.

2007-07-15

This year's Annual Nuclear Technology Conference (JK) organized by the Deutsches Atomforum e.V. (DAtF) and the Kerntechnische Gesellschaft e.V. (KTG) was held in Karlsruhe on May 22-24. The attendance of more than 1,200 persons from 21 nations, and the increase in participation over the past few years, underline the role of this specialized congress as one of the leading international events in the field of the peaceful uses of nuclear power. The first day of the conference, with its plenary presentations, traditionally focused mainly on political and economic problems of the use of nuclear power. The situation of nuclear power in the United Kingdom, the key country of this year's meeting, was covered in depth. As usual, the program of the three-day event was organized as follows: plenary sessions on the first day were followed by topical sessions, technical sessions, and special events on the other days. This year, the conference featured a record program of 251 papers presented at these sessions. The 'Nuclear Power Campus' was arranged very successfully for the 5th time as an event comprising lectures and a 'hands-on' exhibition explaining the world of nuclear power in a transparent way to students from schools and universities. The special commitment to young scientists and to the preservation of competence in the nuclear field were emphasized at the JK 2007, among other things, in a workshop on 'Preservation of Competence in Nuclear Technology'. Nearly 20 young scientists presented results of their scientific work. The Annual Meeting on Nuclear Technology was accompanied by a specialized exhibition with meeting points of industry organized by 33 manufacturers, vendors, and service companies. (orig.)

Genome-wide analysis of ATP-binding cassette (ABC) transporters in the sweetpotato whitefly, Bemisia tabaci.

Science.gov (United States)

Tian, Lixia; Song, Tianxue; He, Rongjun; Zeng, Yang; Xie, Wen; Wu, Qingjun; Wang, Shaoli; Zhou, Xuguo; Zhang, Youjun

2017-04-26

ABC transporter superfamily is one of the largest and ubiquitous groups of proteins. Because of their role in detoxification, insect ABC transporters have gained more attention in recent years. In this study, we annotated ABC transporters from a newly sequenced sweetpotato whitefly genome. Bemisia tabaci Q biotype is an emerging global invasive species that has caused extensive damages to field crops as well as ornamental plants. A total of 55 ABC transporters containing all eight described subfamilies (A to H) were identified in the B. tabaci Q genome, including 8 ABCAs, 3 ABCBs, 6 ABCCs, 2 ABCDs, 1 ABCE, 3 ABCFs, 23 ABCGs and 9 ABCHs. In comparison to other species, subfamilies G and H in both phloem- and blood-sucking arthropods are expanded. The temporal expression profiles of these 55 ABC transporters throughout B. tabaci developmental stages and their responses to imidacloprid, a neonicotinoid insecticide, were investigated using RNA-seq analysis. Furthermore, the mRNA expression of 24 ABC transporters (44% of the total) representing all eight subfamilies was confirmed by the quantitative real-time PCR (RT-qPCR). Furthermore, mRNA expression levels estimated by RT-qPCR and RNA-seq analyses were significantly correlated (r = 0.684, p analysis of the entire repertoire of ABC transporters in B. tabaci. The identification of these ABC transporters, their temporal expression profiles during B. tabaci development, and their response to a neonicotinoid insecticide lay the foundation for functional genomic understanding of their contribution to the invasiveness of B. tabaci.

69th Annual Meeting | Annual Meetings | Events | Indian Academy of ...

Indian Academy of Sciences (India)

14.00 - 17.00. Symposium - Emerging trends in communication technologies. 14.00 - 14.20 ... Towards understanding the genesis of phosphorite deposits ... DISCUSSION MEETING: HUMAN DIVERSITY AND ANCESTRY IN INDIA. Posted on ...

80th Annual Meeting | Annual Meetings | Events | Indian Academy of ...

Indian Academy of Sciences (India)

Current status and future prospects of neutrino mass measurement. View presentation ... Business Meeting of Fellows. 17.00. High Tea ... Hints of 'Beyond Standard Model' cosmology in the cosmic microwave background. View presentation.

Proceedings of the 2. 2000 energy meetings

International Nuclear Information System (INIS)

2000-11-01

The energy meetings is the biggest annual event for French local communities in the energy domain. The public is mainly composed of officials, representatives from local communities, institutions, private organisations and associations. The aim of the meetings is to debate and exchange on the actions to be implemented at the regional scale by local authorities in order to meet the climate and energy challenges of the century. The residential sector is a core issue for the development of renewable energy sources and the reduction of greenhouse gases energy bill: improving buildings and appliances efficiency represent major areas of development. This second edition of the energy meetings was organised around 1 plenary session and 16 workshops. These proceedings brings together the available material: a detailed programme, a summary of the meetings, a synthesis of the workshops, and the abstracts describing each workshop

64th Annual Meeting of the Austrian Physical Society

International Nuclear Information System (INIS)

2014-01-01

The 64th Annual Meeting of the Austrian physical society, including a special topical Energy Day. was held at the Echophysics – European Centre for the History of Physics, Schloss Pöllau 1, 8225 Pöllau, Austria. The plenary sessions gave an overview of the present status of research in quantum mechanics, particle physics and solid state physics.The topical sessions were dedicated to: nuclear and particle physics; atoms, molecules, quantum optics and plasmas; solid state physics and research with neutron and synchrotron radiation; history of physics; surfaces, interfaces and thin films; nanostructures; fundamental interactions; gravity, quantum chromodynamics; particle theory and collider physics; detectors and methods. Those contributions which are in the INIS subject scope are indexed individually

10th Annual Meeting of the Bulgarian Section of SIAM

CERN Document Server

Todorov, Michail; Georgiev, Ivan

2017-01-01

This book presents recent research on Advanced Computing in Industrial Mathematics, which is one of the most prominent interdisciplinary areas and combines mathematics, computer science, scientific computations, engineering, physics, chemistry, medicine, etc. Further, the book presents the tools of Industrial Mathematics, which are based on mathematical models, and the corresponding computer codes, which are used to perform virtual experiments to obtain new data or to better understand the existing experimental results. The book gathers the peer-reviewed papers presented during the 10th Annual Meeting of the Bulgarian Section of SIAM (BGSIAM) from December 21 to 22, 2015 in Sofia, Bulgaria.

INTEGRATING ABC AND EVA TO EVALUATE INVESTMENT DECISIONS

Directory of Open Access Journals (Sweden)

N. Chiadamrong

2017-12-01

Full Text Available The significance of investment is transparent in the world of competitive business. Traditional costing systems in which their emphasizes are for short term savings rather than long term benefits have shown some lacking in providing accurate and reliable cost data for the investment decisions. Activity-based Costing (ABC, which is developed to satisfy some of the weaknesses of the traditional costing systems, can provide valuable insights into the operating processes and come up with more accurate cost data. In this paper, ABC is used to provide significant information for investment decisions. Although, the ABC method provides accurate operating product costs, it does not identify which products are economic valued added creators and so contribute to companies’ wealth. This drawback can be overcome by applying Economic Value Added (EVA. The adoption of ABC and EVA can represent a considerable change in the managerial thinking and to corporate strategies and business performance.

Preconceptual ABC design definition and system configuration layout: Appendix A

International Nuclear Information System (INIS)

1995-03-01

The mission of the ABC system is to destroy as effectively as possible the fissile material inserted into the core without producing any new fissile material. The contents of this report are as follows: operating conditions for the steam-cycle ABC system; flow rates and component dimensions; drawings of the ABC layout; and impact of core design parameters on containment size

Genome-wide comparative analysis of ABC systems in the Bdellovibrio-and-like organisms.

Science.gov (United States)

Li, Nan; Chen, Huan; Williams, Henry N

2015-05-10

Bdellovibrio-and-like organisms (BALOs) are gram-negative, predatory bacteria with wide variations in genome sizes and GC content and ecological habitats. The ATP-binding cassette (ABC) systems have been identified in several prokaryotes, fungi and plants and have a role in transport of materials in and out of cells and in cellular processes. However, knowledge of the ABC systems of BALOs remains obscure. A total of 269 putative ABC proteins were identified in BALOs. The genes encoding these ABC systems occupy nearly 1.3% of the gene content in freshwater Bdellovibrio strains and about 0.7% in their saltwater counterparts. The proteins found belong to 25 ABC system families based on their structural characteristics and functions. Among these, 16 families function as importers, 6 as exporters and 3 are involved in various cellular processes. Eight of these 25 ABC system families were deduced to be the core set of ABC systems conserved in all BALOs. All Bacteriovorax strains have 28 or less ABC systems. On the contrary, the freshwater Bdellovibrio strains have more ABC systems, typically around 51. In the genome of Bdellovibrio exovorus JSS (CP003537.1), 53 putative ABC systems were detected, representing the highest number among all the BALO genomes examined in this study. Unexpected high numbers of ABC systems involved in cellular processes were found in all BALOs. Phylogenetic analysis suggests that the majority of ABC proteins can be assigned into many separate families with high bootstrap supports (>50%). In this study, a general framework of sequence-structure-function connections for the ABC systems in BALOs was revealed providing novel insights for future investigations. Copyright © 2015 Elsevier B.V. All rights reserved.

ABCs of Being Smart: S Is for Supporting

Science.gov (United States)

Foster, Joanne

2014-01-01

Joanne Foster's article "R We There Yet?" was first published in "Parenting for High Potential" ("PHP") in 2006, which became the springboard for the "ABCs of Being Smart" series of columns. At that time, Foster invited "PHP" readers to think about their own versions of the "ABCs of Being…

78th Annual Meeting | Annual Meetings | Events | Indian Academy of ...

Indian Academy of Sciences (India)

V. RAVI, National Institute of Mental Health and Neurosciences, Bengaluru A novel technology for ... Himalayan tectonic model and the strong–great earthquakes. 17.30 - 18.00. Tea break ... Business Meeting of Fellows. 17.30. Tea break.

Status of national programmes on fast breeder reactors. Eighteenth annual meeting, Vienna, Austria, 16-19 April 1985

International Nuclear Information System (INIS)

1986-02-01

The Eighteenth Annual Meeting on the Status of National Programmes in Member States of the IAEA on Fast Breeder Reactors had been held in April 1985. The representatives of the Member States and international organizations reported status and activities in the field of fast breeder reactors development and operation. A separate abstract was prepared for each of the 12 presentations of the meeting

76th Annual Meeting | Annual Meetings | Events | Indian Academy of ...

Indian Academy of Sciences (India)

Structural materials for the future: The case of bulk metallic glasses ... Cell therapy for ocular surface: A successful model of regenerative medicine. 11.45. SHUBHA TOLE, Tata ... Business Meeting of Fellows (Seminar Hall). 17.30 - 18.00.

68th Annual Meeting | Annual Meetings | Events | Indian Academy of ...

Indian Academy of Sciences (India)

Optical technologies for space imaging. 11.30 - 12.00. Sunil Mukhi ... Y. D. Vankar, Indian Institute of Technology Kanpur Carbohydrates: much ... 14.00 - 19.00. Business meeting of Fellows, and sightseeing ... and Outreach. Math and Finance ...

A Compute Environment of ABC95 Array Computer Based on Multi-FPGA Chip

Institute of Scientific and Technical Information of China (English)

无

2000-01-01

ABC95 array computer is a multi-function network's computer based on FPGA technology, The multi-function network supports processors conflict-free access data from memory and supports processors access data from processors based on enhanced MESH network.ABC95 instruction's system includes control instructions, scalar instructions, vectors instructions.Mostly net-work instructions are introduced.A programming environment of ABC95 array computer assemble language is designed.A programming environment of ABC95 array computer for VC++ is advanced.It includes load function of ABC95 array computer program and data, store function, run function and so on.Specially, The data type of ABC95 array computer conflict-free access is defined.The results show that these technologies can develop programmer of ABC95 array computer effectively.

77th Annual Meeting | Annual Meetings | Events | Indian Academy of ...

Indian Academy of Sciences (India)

... Proceedings – Mathematical Sciences · Resonance – Journal of Science Education · Sadhana · Current Science ... Venue : Physical Research Laboratory, Ahmedabad ... K. R. GOPIDAS, National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram ... Business Meeting of Fellows (Seminar Hall).

Idaho National Laboratory PCB Annual Document Log and Annual Records Report for calendar year 2014

Energy Technology Data Exchange (ETDEWEB)

Layton, Deborah L. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2015-06-01

The requirements for the reporting of polychlorinated biphenyl (PCB)-related activities are found in 40 Code of Federal Regulations (CFR) 761 Subpart J, "General Records and Reports." The PCB Annual Document Log is a detailed record of the PCB waste handling activities at the facility. The facility must prepare it each year by July 1 and maintain it at the facility for at least 3 years after the facility ceases using or storing PCBs and PCB items. While submittal of the PCB Annual Document Log to the U.S. Environmental Protection Agency (EPA) is not required by regulation, EPA has verbally requested in telephone conversations that this report be submitted to them on an annual basis. The Annual Records are not required to be submitted to EPA and are not considered to be part of the Annual Document Log, but are included to provide the complete disposition history or status of all PCB activities during the year. The Annual Document Log section of this report (Section 2.0) meets the requirements of 40 CFR 761.180(a)(2), as applicable, while the Annual Records section (Section 3.0) meets the requirement of 40 CFR 761.180(a)(1).

Proceedings of the 2009 annual meeting of the Fetal Alcohol Spectrum Disorders Study Group.

Science.gov (United States)

Zhou, Feng C; Kane, Cynthia J M; Smith, Susan M

2012-02-01

The annual meeting of the Fetal Alcohol Spectrum Disorders Study Group (FASDSG) was held on June 20, 2009 in San Diego, CA, as a satellite of the Research Society on Alcoholism Meeting. The FASDSG membership includes clinical, basic, and social scientists who meet to discuss recent advances and issues in Fetal Alcohol Spectrum Disorders research. The main theme of the meeting was "Epigenetics and Development." Two keynote speakers, Dr. Randy Jirtle and Dr. Michael Skinner, addressed the role of epigenetics and environmental inputs, including alcohol, during critical stages of development and their potential critical and long-lasting effects. Members of the FASDSG provided new findings through brief "FASt" data reports, and national agency representatives provided updates on activities and funding priorities. Scientific presentations were made by recipients of the Student Research Merit Award and Rosett Award. Copyright © 2012 Elsevier Inc. All rights reserved.

proceedings of the 11. Annual meeting of the Federation of Societies on Experimental Biology

International Nuclear Information System (INIS)

1996-01-01

The proceedings of the 11. Annual meeting of the Federation of Societies on Experimental Biology contains 1850 abstracts, which include the following topics: neuroscience and behaviour; biophysics; pharmacology; comparative physiology; nervous regulation; endocrinology; nefrology; vascular biology; toxicity; molecular biophysics; radiobiology and others. Among these, 169 abstracts have been indexed separately for the INIS database

[Brief Report on the 69th Annual Meeting of the Japanese Cancer Association - Conquering Cancer with Collective Wisdom].

Science.gov (United States)

Tsukagoshi, Shigeru

2010-11-01

The 69th Annual Meeting was held from September 22nd through 24th, at Osaka International Convention Center and RIHGA ROYAL HOTEL Osaka. The president of this meeting was professor Morito Monden, Osaka University Medical School. In this meeting, there were many scientific meetings including Special Remarks, symposiums, workshops, international sessions, oral and poster sessions and others, English workshops, morning lectures. Especially, as a special session, Now, what are the elements expected to cancer research ? - Special proposals for cancer research, was one of the most impressive session among many.

Eleventh annual meeting, Bologna, Italy, 17-20 April 1978. Summary report. Part II

Energy Technology Data Exchange (ETDEWEB)

NONE

1978-07-01

The Summary Report - Part II of the Eleventh Annual Meeting of the IAEA International Working Group on Fast Reactors - includes reports on development of fast reactors in France from 1977 to 1978; review of the activities related to fast reactors in Germany; status of fast breeder reactors development in Belgium and Netherlands; status of activities related to fast reactors in USSR, Japan USA, UK and Italy.

Eleventh annual meeting, Bologna, Italy, 17-20 April 1978. Summary report. Part II

International Nuclear Information System (INIS)

1978-07-01

The Summary Report - Part II of the Eleventh Annual Meeting of the IAEA International Working Group on Fast Reactors - includes reports on development of fast reactors in France from 1977 to 1978; review of the activities related to fast reactors in Germany; status of fast breeder reactors development in Belgium and Netherlands; status of activities related to fast reactors in USSR, Japan USA, UK and Italy

Meeting Report of the 33rd Annual Meeting of the Academy of Surgical Research: Summary of Presentations, Labs, and Workshops, Focusing on Experimental Surgery, Las Vegas, NV, October 4-6, 2017.

Science.gov (United States)

Graham, Melanie L; Ziegelhofer, Tracy; Ehrmann, Jon

2018-04-11

The 33rd Annual Meeting of the Academy of Surgical Research was held from October 4 to 6, 2017 in Las Vegas, Nevada. The meeting welcomed >160 participants from 27 different states and five countries representing the organization's diverse membership of technicians, veterinarians, medical doctors, and biomedical researchers. The Academy's annual meeting is focused on promoting the advancement of professional and academic standards, education, and research related to the art and science of experimental surgery. Presentations included four invited keynote speakers and 30 selected lectures and posters. A primary strength of the meeting was that lectures were complimented with practical sessions that included four wet lab and two dry lab half-day courses. Likewise, participants were brought together in workshops emphasizing research workflow from starting experimental design to readying results for publication. In this report, we present the highlights from this meeting and some selected abstracts that illustrate the diverse scientific expertise of the Academy and progress in surgical research.

Forty-Fifth Annual Meeting of the Technical Working Group on Fast Reactors (TWG-FR). Presentations

International Nuclear Information System (INIS)

2012-01-01

The objectives of the meeting were to: • Exchange information on the national programmes on Fast Reactors (FR) and Accelerator Driven Systems (ADS); • Review the progress since the 44 th TWG-FR Annual Meeting, including the status of the actions; • Consider topical technical meeting arrangements for 2012-2013, as well as review FR-related activities included in the IAEA Programme & Budget (P&B) biennium 2012-2013; • Review the IAEA’s concluded, on-going and planned coordinated research projects in the technical fields relevant to the TWG-FR (FRs and ADS), as well as coordination of the TWG-FR’s activities with other organizations and international initiatives (GIF, INPRO, NEA, ESNII, etc.)

48. Annual meeting of the Deutsche Gesellschaft fuer Neuroradiologie. Joint annual meeting of the DGNR and OeGNR. Abstracts; 48. Jahrestagung der Deutschen Gesellschaft fuer Neuroradiologie. Gemeinsame Jahrestagung der DGNR und OeGNR. Abstracts

Energy Technology Data Exchange (ETDEWEB)

NONE

2013-09-15

The conference proceedings of the 48. Annual meeting of the Deutsche Gesellschaft fuer Neuroradiologie contain abstracts on the following issues: neuro-oncological imaging, multimodal imaging concepts, subcranial imaging, spinal codes, interventional neuroradiology, innovative techniques like high-field MRT and hybrid imaging methods, inflammable and metabolic central nervous system diseases and epilepsy.

Politseiniku lustlik ABC / Pekka Erelt

Index Scriptorium Estoniae

Erelt, Pekka, 1965-

1999-01-01

Politsei on välja andnud 'Politseiniku ABC', mis antakse igale politseinikule. Karikaturist Heiki Ernits on peaaegu igale taskuraamatu leheküljele joonistanud pildikese mundrimeestest kentsakates situatsioonides.

Optimization of Straight Cylindrical Turning Using Artificial Bee Colony (ABC) Algorithm

Science.gov (United States)

Prasanth, Rajanampalli Seshasai Srinivasa; Hans Raj, Kandikonda

2017-04-01

Artificial bee colony (ABC) algorithm, that mimics the intelligent foraging behavior of honey bees, is increasingly gaining acceptance in the field of process optimization, as it is capable of handling nonlinearity, complexity and uncertainty. Straight cylindrical turning is a complex and nonlinear machining process which involves the selection of appropriate cutting parameters that affect the quality of the workpiece. This paper presents the estimation of optimal cutting parameters of the straight cylindrical turning process using the ABC algorithm. The ABC algorithm is first tested on four benchmark problems of numerical optimization and its performance is compared with genetic algorithm (GA) and ant colony optimization (ACO) algorithm. Results indicate that, the rate of convergence of ABC algorithm is better than GA and ACO. Then, the ABC algorithm is used to predict optimal cutting parameters such as cutting speed, feed rate, depth of cut and tool nose radius to achieve good surface finish. Results indicate that, the ABC algorithm estimated a comparable surface finish when compared with real coded genetic algorithm and differential evolution algorithm.

Acid mine water reclamation using the ABC process

CSIR Research Space (South Africa)

De Beer, Morris

2010-09-01

Full Text Available of about 2 to 4.5 g/L of sulphate, 250 to 1200 mg/L of Ferrous iron, 60 to 175 mg/L of Mn and 120 mg/L of Mg. The CSIR ABC desalination process, developed for AMD neutralisation and the removal of total dissolved solids from 2 600 to 360 mg/L...

Adsorption of non-ionic ABC triblock copolymers: Surface modification of TiO2 suspensions in aqueous and non-aqueous medium

Science.gov (United States)

Lerch, Jean-Philippe; Atanase, Leonard Ionut; Riess, Gérard

2017-10-01

A series of non-ionic ABC triblock copolymers, such as poly(butadiene)-b-poly(2-vinylpyrridine)-b-poly(ethylene oxide) (PB-P2VP-PEO) were synthesized by sequential anionic polymerizations. For these copolymers comprising an organo-soluble PB and a water-soluble PEO block, their P2VP middle block has been selected for its anchoring capacity on solid surfaces. The adsorption isotherms on TiO2 were obtained in heptane and in aqueous medium, as selective solvents. In both of these cases, the P2VP middle block provides the surface anchoring, whereas PB and PEO sequences are acting as stabilizing moieties in heptane and water respectively. By extension to ABC triblock copolymers of the scaling theory developed for diblock copolymers, the density of adsorbed chains could be correlated with the molecular characteristics of the PB-P2VP-PEO triblock copolymers. From a practical point a view, it could be demonstrated that these copolymers are efficient dispersing agents for the TiO2 pigments in both aqueous and non-aqueous medium.

Identification of ABC transporters acting in vitamin B12 metabolism in Caenorhabditis elegans.

Science.gov (United States)

McDonald, Megan K; Fritz, Julie-Anne; Jia, Dongxin; Scheuchner, Deborah; Snyder, Floyd F; Stanislaus, Avalyn; Curle, Jared; Li, Liang; Stabler, Sally P; Allen, Robert H; Mains, Paul E; Gravel, Roy A

2017-12-01

Vitamin B 12 (cobalamin, Cbl) is a micronutrient essential to human health. Cbl is not utilized as is but must go through complex subcellular and metabolic processing to generate two cofactor forms: methyl-Cbl for methionine synthase, a cytosolic enzyme; and adenosyl-Cbl for methylmalonyl-CoA mutase, a mitochondrial enzyme. Some 10-12 human genes have been identified responsible for the intracellular conversion of Cbl to cofactor forms, including genes that code for ATP-binding cassette (ABC) transporters acting at the lysosomal and plasma membranes. However, the gene for mitochondrial uptake is not known. We hypothesized that ABC transporters should be candidates for other uptake and efflux functions, including mitochondrial transport, and set out to screen ABC transporter mutants for blocks in Cbl utilization using the nematode roundworm Caenorhabditis elegans. Thirty-seven mutant ABC transporters were screened for the excretion of methylmalonic acid (MMA), which should result from loss of Cbl transport into the mitochondria. One mutant, wht-6, showed elevated MMA excretion and reduced [ 14 C]-propionate incorporation, pointing to a functional block in methylmalonyl-CoA mutase. In contrast, the wht-6 mutant appeared to have a normal cytosolic pathway based on analysis of cystathionine excretion, suggesting that cytosolic methionine synthase was functioning properly. Further, the MMA excretion in wht-6 could be partially reversed by including vitamin B 12 in the assay medium. The human ortholog of wht-6 is a member of the G family of ABC transporters. We propose wht-6 as a candidate for the transport of Cbl into mitochondria and suggest that a member of the corresponding ABCG family of ABC transporters has this role in humans. Our ABC transporter screen also revealed that mrp-1 and mrp-2 mutants excreted lower MMA than wild type, suggesting they were concentrating intracellular Cbl, consistent with the cellular efflux defect proposed for the mammalian MRP1 ABC

Application of activity-based costing (ABC) for a Peruvian NGO healthcare provider.

Science.gov (United States)

Waters, H; Abdallah, H; Santillán, D

2001-01-01

This article describes the application of activity-based costing (ABC) to calculate the unit costs of the services for a health care provider in Peru. While traditional costing allocates overhead and indirect costs in proportion to production volume or to direct costs, ABC assigns costs through activities within an organization. ABC uses personnel interviews to determine principal activities and the distribution of individual's time among these activities. Indirect costs are linked to services through time allocation and other tracing methods, and the result is a more accurate estimate of unit costs. The study concludes that applying ABC in a developing country setting is feasible, yielding results that are directly applicable to pricing and management. ABC determines costs for individual clinics, departments and services according to the activities that originate these costs, showing where an organization spends its money. With this information, it is possible to identify services that are generating extra revenue and those operating at a loss, and to calculate cross subsidies across services. ABC also highlights areas in the health care process where efficiency improvements are possible. Conclusions about the ultimate impact of the methodology are not drawn here, since the study was not repeated and changes in utilization patterns and the addition of new clinics affected applicability of the results. A potential constraint to implementing ABC is the availability and organization of cost information. Applying ABC efficiently requires information to be readily available, by cost category and department, since the greatest benefits of ABC come from frequent, systematic application of the methodology in order to monitor efficiency and provide feedback for management. The article concludes with a discussion of the potential applications of ABC in the health sector in developing countries.

Idaho National Laboratory PCB Annual Document Log and Annual Records Report for Calendar Year 2013

Energy Technology Data Exchange (ETDEWEB)

no name on report

2014-06-01

The requirements for the reporting of polychlorinated biphenyl (PCB)-related activities are found in 40 Code of Federal Regulations (CFR) 761 Subpart J, "General Records and Reports." The PCB Annual Document Log is a detailed record of the PCB waste handling activities at the facility. The facility must prepare it each year by July 1 and maintain it at the facility for at least 3 years after the facility ceases using or storing PCBs and PCB items. While submittal of the PCB Annual Document Log to the U.S. Environmental Protection Agency (EPA) is not required by regulation, EPA has verbally requested in telephone conversations that this report be submitted to them on an annual basis. The Annual Document Log section of this report meets the requirements of 40 CFR 761.180(a)(2), as applicable, while the Annual Records section meets the requirement of 40 CFR 761.180(a)(1).

Building Bridges between Researchers and Patient Research Partners: A Report from the GRAPPA 2014 Annual Meeting

NARCIS (Netherlands)

de Wit, M.P.T.; Campbell, W.; Orbai, A.M.; Tillett, W.; Fitzgerald, O.; Gladman, D.D.; Lindsay, C.A.; McHugh, N.J.; Mease, P.J.; O'Sullivan, D.; Steinkoenig, I.; Windisch, G.; Goel, N.

2015-01-01

for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) recently engaged patients as collaborative partners in psoriatic arthritis (PsA) research. We summarize Building Bridges, a session held at the GRAPPA 2014 annual meeting, where interactive dialogue was encouraged between all

Quantitative psychology : The 81st Annual Meeting of the Psychometric Society, Asheville, North Carolina, 2016

NARCIS (Netherlands)

van der Ark, L.A.; Wiberg, M.; Culpepper, S.A.; Douglas, J.A.; Wang, W.-C.

2017-01-01

This proceedings volume compiles and expands on selected and peer reviewed presentations given at the 81st Annual Meeting of the Psychometric Society (IMPS), organized by the University of North Carolina at Greensboro, and held in Asheville, North Carolina, July 11th to 17th, 2016.IMPS is one of the

Prologue: 2017 Annual Meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA).

Science.gov (United States)

Helliwell, Philip S; Gladman, Dafna D; Gottlieb, Alice B

2018-06-01

The 2017 Annual Meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) was held in Amsterdam, the Netherlands, and was attended by rheumatologists, dermatologists, representatives of biopharmaceutical companies, and patients. As in previous years, GRAPPA members held a symposium for trainees to discuss their research in psoriatic disease with experts in the field. Other subjects featured during the annual meeting included a discussion of the history, clinical features, controversies, and immunogenetics of juvenile psoriatic arthritis; updates from working groups in Outcome Measures in Rheumatology and International Dermatology Outcome Measures; a discussion of the benefits and challenges of setting up a longitudinal psoriatic arthritis (PsA) database; 3 separate discussions of the effects of the microbiome on skin and joints in psoriasis and PsA; a discussion of options for assessing joints and entheses in PsA by ultrasonography and magnetic resonance imaging; an update on GRAPPA's research and educational projects; a discussion of patient centricity, including the incorporation of patient research partners (PRP) into psoriasis and PsA research and educational efforts, from GRAPPA's PRP; and a discussion of the GRAPPA-Collaborative Research Network's inaugural meeting. In this prologue, we introduce the papers that summarize that meeting.

Osabc1k8, an abc1-like kinase gene, mediates abscisic acid sensitivity and dehydration tolerance response in rice seedlings

International Nuclear Information System (INIS)

Liu, Y.; Li, T.; Yang, C.

2015-01-01

The activity of bc1 complex kinase (ABC1K) protein family, which widely exists in prokaryotes and eukaryotes, consists of 15 members in rice, and the role of this family in plants has not yet been studied in details. In this study, a novel function of OsABC1K8 (LOC-Os06g48770), a member of rice ABC1K family, was characterized. The transcript level of OsABC1K8 changes in response to salt, dehydration, cold, PEG, oxidative (H/sub 2/O/sub 2/) stresses, or abscisic acid (ABA) treatment. Overexpression of OsABC1K8 significantly increased sensitivity to dehydration and reduced sensitivity to ABA. In the contrast, RNAi transgenic lines displayed significantly reduced sensitivity to dehydration stress and increased sensitivity to ABA. Furthermore, the transcriptional levels of several ABA/stress-regulated responsive genes were suppressed in OsABC1K8 over-expressing plants under dehydration stress. In conclusion, our results suggested that OsABC1K8 is a negative regulator in response to dehydration stress through an ABA-dependent pathway. (author)

Anticipated Benefits of Care (ABC): psychometrics and predictive value in psychiatric disorders.

Science.gov (United States)

Warden, D; Trivedi, M H; Carmody, T J; Gollan, J K; Kashner, T M; Lind, L; Crismon, M L; Rush, A J

2010-06-01

Attitudes and expectations about treatment have been associated with symptomatic outcomes, adherence and utilization in patients with psychiatric disorders. No measure of patients' anticipated benefits of treatment on domains of everyday functioning has previously been available. The Anticipated Benefits of Care (ABC) is a new, 10-item questionnaire used to measure patient expectations about the impact of treatment on domains of everyday functioning. The ABC was collected at baseline in adult out-patients with major depressive disorder (MDD) (n=528), bipolar disorder (n=395) and schizophrenia (n=447) in the Texas Medication Algorithm Project (TMAP). Psychometric properties of the ABC were assessed, and the association of ABC scores with treatment response at 3 months was evaluated. Evaluation of the ABC's internal consistency yielded Cronbach's alpha of 0.90-0.92 for patients across disorders. Factor analysis showed that the ABC was unidimensional for all patients and for patients with each disorder. For patients with MDD, lower anticipated benefits of treatment was associated with less symptom improvement and lower odds of treatment response [odds ratio (OR) 0.72, 95% confidence interval (CI) 0.57-0.87, p=0.0011]. There was no association between ABC and symptom improvement or treatment response for patients with bipolar disorder or schizophrenia, possibly because these patients had modest benefits with treatment. The ABC is the first self-report that measures patient expectations about the benefits of treatment on everyday functioning, filling an important gap in available assessments of attitudes and expectations about treatment. The ABC is simple, easy to use, and has acceptable psychometric properties for use in research or clinical settings.

Object Detection Based on Template Matching through Use of Best-So-Far ABC

Directory of Open Access Journals (Sweden)

Anan Banharnsakun

2014-01-01

Full Text Available Best-so-far ABC is a modified version of the artificial bee colony (ABC algorithm used for optimization tasks. This algorithm is one of the swarm intelligence (SI algorithms proposed in recent literature, in which the results demonstrated that the best-so-far ABC can produce higher quality solutions with faster convergence than either the ordinary ABC or the current state-of-the-art ABC-based algorithm. In this work, we aim to apply the best-so-far ABC-based approach for object detection based on template matching by using the difference between the RGB level histograms corresponding to the target object and the template object as the objective function. Results confirm that the proposed method was successful in both detecting objects and optimizing the time used to reach the solution.

The ABC of handover: impact on shift handover in the emergency department.

Science.gov (United States)

Farhan, Maisse; Brown, Ruth; Vincent, Charles; Woloshynowych, Maria

2012-12-01

A study was undertaken to test the impact of a new tool for shift handover, 'The ABC of Handover', in the emergency department (ED). The impact on shift handover following implementation of this structured tool, the effect on clinical and organisational aspects of the subsequent shift and the opinions of users of this new tool are reported. A prospective observational before and after study was performed to explore the effect of implementing 'The ABC of Handover' on clinical and organisational practice using a questionnaire. 41 handovers were observed before implementation of 'The ABC of Handover' and 42 were observed after. The new tool was successfully implemented and resulted in a change of practice which led to a significant increase in the operational issues mentioned at handover from a mean of 34% to a mean of 86% of essential items with the ABC method. Over the study period, middle-grade staff demonstrated improved situational awareness as they adopted proactive management of operational issues such as staffing or equipment shortages. All participants reported that 'The ABC of Handover' improved handover regardless of the seniority of the doctor giving it, and found the ABC method easy to learn. Successful implementation of 'The ABC of Handover' led to a change of practice in the ED. Improving handover resulted in better organisation of the shift and heightened awareness of potential patient safety issues. The ABC method provides a framework for organising the shift and preparing for events in the subsequent shift.

47{sup th} Annual meeting on nuclear technology (AMNT 2016). Opening address

Energy Technology Data Exchange (ETDEWEB)

Gueldner, Ralf [Deutsches Atomforum e.V. (DAtF), Berlin (Germany)

2016-06-15

The 47{sup th} Annual Meeting on Nuclear Technology (AMNT 2016) was an excellent opportunity for a comprehensive outlook on nuclear technology, fostering international exchange in industry, research, politics and administration. Ralf Gueldner, President of the German Atomic Forum (DAtF) talked about important decisions in nuclear energy in Germany in 2016. Finally, Gueldner noticed that even with a phase out, Germany needs nuclear expertise and competent people for the upcoming challenges and international cooperation. In this context, also publicly-financed education and research are indispensable.

75 FR 49466 - New England Fishery Management Council; Public Meeting

Science.gov (United States)

2010-08-13

... Bank yellowtail flounder rebuilding strategies ABCs for stocks including Gulf of Maine winter flounder and pollock Whaleback area spawning closure Permit bank implementation Accountability measures... action to address the emergency. Special Accommodations This meeting is physically accessible to people...

Transcriptomic insights on the ABC transporter gene family in the salmon louse Caligus rogercresseyi.

Science.gov (United States)

Valenzuela-Muñoz, Valentina; Sturm, Armin; Gallardo-Escárate, Cristian

2015-04-09

ATP-binding cassette (ABC) protein family encode for membrane proteins involved in the transport of various biomolecules through the cellular membrane. These proteins have been identified in all taxa and present important physiological functions, including the process of insecticide detoxification in arthropods. For that reason the ectoparasite Caligus rogercresseyi represents a model species for understanding the molecular underpinnings involved in insecticide drug resistance. llumina sequencing was performed using sea lice exposed to 2 and 3 ppb of deltamethrin and azamethiphos. Contigs obtained from de novo assembly were annotated by Blastx. RNA-Seq analysis was performed and validated by qPCR analysis. From the transcriptome database of C. rogercresseyi, 57 putative members of ABC protein sequences were identified and phylogenetically classified into the eight subfamilies described for ABC transporters in arthropods. Transcriptomic profiles for ABC proteins subfamilies were evaluated throughout C. rogercresseyi development. Moreover, RNA-Seq analysis was performed for adult male and female salmon lice exposed to the delousing drugs azamethiphos and deltamethrin. High transcript levels of the ABCB and ABCC subfamilies were evidenced. Furthermore, SNPs mining was carried out for the ABC proteins sequences, revealing pivotal genomic information. The present study gives a comprehensive transcriptome analysis of ABC proteins from C. rogercresseyi, providing relevant information about transporter roles during ontogeny and in relation to delousing drug responses in salmon lice. This genomic information represents a valuable tool for pest management in the Chilean salmon aquaculture industry.

International Working Group on Fast Reactors Eight Annual Meeting, Vienna, Austria, 15-18 April 1975. Summary Report. Part II

International Nuclear Information System (INIS)

1975-07-01

The Eighth Annual Meeting of the IAEA International Working Group on Past Reactors was held at the IAEA Headquarters in Vienna, Austria, from 15 to 18 April 1975. The Summary Report (Part I) contains the Minutes of the Meeting. The Summary Report (Part II) contains the papers which review the national programmes in the field of LMPBR’s and other presentations at the Meeting. The Summary Report (Part III) contains the discussions on the review of the national programmes

Advanced Placement Human Geography and the Annual Meetings of the National Council for Geographic Education

Science.gov (United States)

Sublett, Michael D.

2007-01-01

Members of the National Council for Geographic Education have been instrumental in the creation, launch, and early success of Advanced Placement Human Geography. Annual meetings of the Council have served as a forum for spreading the word about the course and its follow-up national examination and in helping teachers develop content confidence and…

Note on the ABC Conjecture

OpenAIRE

Carella, N. A.

2006-01-01

This note imparts heuristic arguments and theorectical evidences that contradict the abc conjecture over the rational numbers. In addition, the rudimentary datails for transforming this problem into the doimain of equidistribution theory are provided.

ABC optimized RBF network for classification of EEG signal for epileptic seizure identification

Directory of Open Access Journals (Sweden)

Sandeep Kumar Satapathy

2017-03-01

Full Text Available The brain signals usually generate certain electrical signals that can be recorded and analyzed for detection in several brain disorder diseases. These small signals are expressly called as Electroencephalogram (EEG signals. This research work analyzes the epileptic disorder in human brain through EEG signal analysis by integrating the best attributes of Artificial Bee Colony (ABC and radial basis function networks (RBFNNs. We have used Discrete Wavelet Transform (DWT technique for extraction of potential features from the signal. In our study, for classification of these signals, in this paper, the RBFNNs have been trained by a modified version of ABC algorithm. In the modified ABC, the onlooker bees are selected based on binary tournament unlike roulette wheel selection of ABC. Additionally, kernels such as Gaussian, Multi-quadric, and Inverse-multi-quadric are used for measuring the effectiveness of the method in numerous mixtures of healthy segments, seizure-free segments, and seizure segments. Our experimental outcomes confirm that RBFNN with inverse-multi-quadric kernel trained with modified ABC is significantly better than RBFNNs with other kernels trained by ABC and modified ABC.

Abrasive wear behavior of heat-treated ABC-silicon carbide

Energy Technology Data Exchange (ETDEWEB)

Zhang, Xiao Feng; Lee, Gun Y.; Chen, Da; Ritchie, Robert O.; De Jonghe, Lutgard C.

2002-06-17

Hot-pressed silicon carbide, containing aluminum, boron, and carbon additives (ABC-SiC), was subjected to three-body and two-body wear testing using diamond abrasives over a range of sizes. In general, the wear resistance of ABC-SiC, with suitable heat treatment, was superior to that of commercial SiC.

A burst of ABC genes in the genome of the polyphagous spider mite Tetranychus urticae.

Science.gov (United States)

Dermauw, Wannes; Osborne, Edward John; Clark, Richard M; Grbić, Miodrag; Tirry, Luc; Van Leeuwen, Thomas

2013-05-10

The ABC (ATP-binding cassette) gene superfamily is widespread across all living species. The majority of ABC genes encode ABC transporters, which are membrane-spanning proteins capable of transferring substrates across biological membranes by hydrolyzing ATP. Although ABC transporters have often been associated with resistance to drugs and toxic compounds, within the Arthropoda ABC gene families have only been characterized in detail in several insects and a crustacean. In this study, we report a genome-wide survey and expression analysis of the ABC gene superfamily in the spider mite, Tetranychus urticae, a chelicerate ~ 450 million years diverged from other Arthropod lineages. T. urticae is a major agricultural pest, and is among of the most polyphagous arthropod herbivores known. The species resists a staggering array of toxic plant secondary metabolites, and has developed resistance to all major classes of pesticides in use for its control. We identified 103 ABC genes in the T. urticae genome, the highest number discovered in a metazoan species to date. Within the T. urticae ABC gene set, all members of the eight currently described subfamilies (A to H) were detected. A phylogenetic analysis revealed that the high number of ABC genes in T. urticae is due primarily to lineage-specific expansions of ABC genes within the ABCC, ABCG and ABCH subfamilies. In particular, the ABCC subfamily harbors the highest number of T. urticae ABC genes (39). In a comparative genomic analysis, we found clear orthologous relationships between a subset of T. urticae ABC proteins and ABC proteins in both vertebrates and invertebrates known to be involved in fundamental cellular processes. These included members of the ABCB-half transporters, and the ABCD, ABCE and ABCF families. Furthermore, one-to-one orthologues could be distinguished between T. urticae proteins and human ABCC10, ABCG5 and ABCG8, the Drosophila melanogaster sulfonylurea receptor and ecdysone-regulated transporter E

14. Annual meeting of the European Society of Radiobiology and the symposium of the European Late Effects Project Group

International Nuclear Information System (INIS)

Charles, M.W.

1979-03-01

In October 1978 the Fourteenth Annual Meeting of the European Society of Radiation Biology (ESRB) and a symposium of the European Late Effects Project Group (EULEP) were held consecutively at the Kernforchungsanlage (KFA), Julich, FDR. The EULEP meeting was convened to specifically discuss the biological basis of the recommendations of publication 26 of the International Commission on Radiological Protection (ICRP). The programme of the ESRB Meeting also reflected the present interest in radiological protection. A short summary of these meetings is presented. Details of the two meetings are given in appendices which should form an introduction to, and resume of, recent developments in this field. (author)

A burst of ABC genes in the genome of the polyphagous spider mite Tetranychus urticae

NARCIS (Netherlands)

Dermauw, W.; Osborne, E.J.; Clark, R.M.; Grbić, M.; Tirry, L.; Van Leeuwen, T.

2013-01-01

Background: The ABC (ATP-binding cassette) gene superfamily is widespread across all living species. The majority of ABC genes encode ABC transporters, which are membrane-spanning proteins capable of transferring substrates across biological membranes by hydrolyzing ATP. Although ABC transporters

Symposium on Current Research in the Chemical Sciences: Third Annual Southern Station Chemical Sciences Meeting

Science.gov (United States)

Timothy G. Rials; [Editor

1994-01-01

The original charter for this annual meeting of chemical sciences personnel called for an informal atmosphere for the discussion of common concerns and needs. The years have seen the definition of our "common concern" evolve into a sharing of our efforts in applying the science of chemistry to the resolution of problems faced by our forest resource. I believe...

Quantitative Assessment of the Association between ABC Polymorphisms and Osteosarcoma Response: a Meta-analysis.

Science.gov (United States)

Chen, Xu; Jiang, Min; Zhao, Rui-Ke; Gu, Guo-Hao

2015-01-01

ABC proteins are one key type of transport superfamilies which undertake majority of drug transport, which affect the osteosarcoma response to chemotherapeutics. Previous studies have suggested the association between ABC polymorphisms and osteosarcoma response. However, the results of previous studies remain controversial. Therefore, we perform a meta-analysis to get a more precise estimation of this association. The association between ABC polymorphisms and osteosarcoma response was assessed by odds ratios (ORs) together with their 95% confidence intervals (CIs). Three polymorphisms of ABC including ABCB1 rs1128503, ABCC3 rs4148416 and ABCC2 rs717620 polymorphism were investigated. Overall, significant association was observed between ABCC3 rs4148416 polymorphism and osteosarcoma response under allele contrast (T vs. C: OR=1.73, 95%CI=1.09-2.74, P=0.019), homozygote comparison (TT vs. CC: OR=2.00, 95%CI=1.25-3.23, P=0.004), recessive genetic model (TT vs. OR=1.80, 95%CI=1.14-2.84, P=0.011) and dominant genetic model (TT/TC vs. CC: OR=1.70, 95%CI=1.20-2.42, P=0.003). Moreover, significant association was also observed in Caucasian population rather than Asian population for ABCB1 rs1128503 polymorphism. We conclude that ABCC3 rs4148416 polymorphism was significantly associated with poor osteosarcoma response and ABCB1 rs1128503 polymorphism was significantly associated with good osteosarcoma response in Caucasian population rather than Asian population.

Pharmacogenomics of the human ABC transporter ABCG2: from functional evaluation to drug molecular design

Science.gov (United States)

Ishikawa, Toshihisa; Tamura, Ai; Saito, Hikaru; Wakabayashi, Kanako; Nakagawa, Hiroshi

2005-10-01

In the post-genome-sequencing era, emerging genomic technologies are shifting the paradigm for drug discovery and development. Nevertheless, drug discovery and development still remain high-risk and high-stakes ventures with long and costly timelines. Indeed, the attrition of drug candidates in preclinical and development stages is a major problem in drug design. For at least 30% of the candidates, this attrition is due to poor pharmacokinetics and toxicity. Thus, pharmaceutical companies have begun to seriously re-evaluate their current strategies of drug discovery and development. In that light, we propose that a transport mechanism-based design might help to create new, pharmacokinetically advantageous drugs, and as such should be considered an important component of drug design strategy. Performing enzyme- and/or cell-based drug transporter, interaction tests may greatly facilitate drug development and allow the prediction of drug-drug interactions. We recently developed methods for high-speed functional screening and quantitative structure-activity relationship analysis to study the substrate specificity of ABC transporters and to evaluate the effect of genetic polymorphisms on their function. These methods would provide a practical tool to screen synthetic and natural compounds, and these data can be applied to the molecular design of new drugs. In this review article, we present an overview on the genetic polymorphisms of human ABC transporter ABCG2 and new camptothecin analogues that can circumvent AGCG2-associated multidrug resistance of cancer.

Eleventh annual meeting, Bologna, Italy, 17-20 April 1978. Summary report. Part III

International Nuclear Information System (INIS)

1978-09-01

The Summary Report - Part III of the Eleventh Annual Meeting of the IAEA International Working Group on Fast Reactors - contains the discussions on the commercialization LMFBRs according to national plans, mostly related to technology of fuel fabrication, PHENIX fuel pins testing, heterogeneous cores, in service inspection of fuel elements, regulations and licensing, and related OECD activities. Most of the discussions were related to the existing reactors: BR-10, BN-600, BN-350, BN-1600, RAPSODIE and PHENIX

Eleventh annual meeting, Bologna, Italy, 17-20 April 1978. Summary report. Part III

Energy Technology Data Exchange (ETDEWEB)

NONE

1978-09-01

The Summary Report - Part III of the Eleventh Annual Meeting of the IAEA International Working Group on Fast Reactors - contains the discussions on the commercialization LMFBRs according to national plans, mostly related to technology of fuel fabrication, PHENIX fuel pins testing, heterogeneous cores, in service inspection of fuel elements, regulations and licensing, and related OECD activities. Most of the discussions were related to the existing reactors: BR-10, BN-600, BN-350, BN-1600, RAPSODIE and PHENIX.

Accuracy of shock index versus ABC score to predict need for massive transfusion in trauma patients.

Science.gov (United States)

Schroll, Rebecca; Swift, David; Tatum, Danielle; Couch, Stuart; Heaney, Jiselle B; Llado-Farrulla, Monica; Zucker, Shana; Gill, Frances; Brown, Griffin; Buffin, Nicholas; Duchesne, Juan

2018-01-01

Various scoring systems have been developed to predict need for massive transfusion in traumatically injured patients. Assessments of Blood Consumption (ABC) score and Shock Index (SI) have been shown to be reliable predictors for Massive Transfusion Protocol (MTP) activation. However, no study has directly compared these two scoring systems to determine which is a better predictor for MTP activation. The primary objective was to determine whether ABC or SI better predicted the need for MTP in adult trauma patients with severe hemorrhage. This was a retrospective cohort study which included all injured patients who were trauma activations between January 1, 2009 and December 31, 2013 at an urban Level I trauma center. Patients ABC and SI were calculated for each patient. MTP was defined as need for >10 units PRBC transfusion within 24h of emergency department arrival. Sensitivity, specificity, and area under the receiver operating characteristic curve (AUROC) were used to evaluate scoring systems' ability to predict effective MTP utilization. A total of 645 patients had complete data for analysis. Shock Index ≥1 had sensitivity of 67.7% (95% CI 49.5%-82.6%) and specificity of 81.3% (95% CI 78.0%-84.3%) for predicting MTP, and ABC score ≥2 had sensitivity of 47.0% (95% CI 29.8%-64.9%) and specificity of 89.8% (95% CI 87.2%-92.1%). AUROC analyses showed SI to be the strongest predictor followed by ABC score with AUROC values of 0.83 and 0.74, respectively. SI had a significantly greater sensitivity (P=0.035), but a significantly weaker specificity (PABC score. ABC score and Shock Index can both be used to predict need for massive transfusion in trauma patients, however SI is more sensitive and requires less technical skill than ABC score. Copyright © 2017 Elsevier Ltd. All rights reserved.

Rasch Analysis of the Activities-specific Balance Confidence (ABC) Scale in Older Adults Seeking Outpatient Rehabilitation Services.

Science.gov (United States)

Wang, Ying-Chih; Sindhu, Bhagwant; Lehman, Leigh; Li, Xiaoyan; Yen, Sheng-Che; Kapellusch, Jay

2018-03-30

Study Design Cross-sectional study of 5,012 older patients seeking outpatient rehabilitation therapy in 123 clinics. Background The Activities-Specific Balance Confidence (ABC) Scale measures confidence in performing various ambulatory activities without falling or experiencing a sense of unsteadiness. Objectives Our purposes were to: (1) examine the ABC Scale (0-100) using the Rasch analysis, (2) assess statistically reliable change, and (3) develop a functional staging to guide clinical interpretation of the patient's improvement. Methods We examined rating scale structure, item difficulty hierarchy, item fit, person-item match, separation index, differential item functioning (DIF), test precision, and unidimensionality. Additionally, we estimated the minimal detectable change (MDC) and developed a functional staging. Results Item 'walking outside on icy sidewalks' was the most difficult item, while 'reach for a small can off a shelf at eye level' was the easiest item. Overall, average patient ability estimates of 56.2 (20.3) was slightly higher than the average item difficulty estimates of 45.9 (7.8). With a separation index equaled to 3.65, the ABC items can differentiate persons into 5.2 statistically distinct strata. Most ABC items were free of DIF. For example, 'walk outside on icy sidewalks' was easier for patients who was underweight. Results supported unidimensionality of the ABC Scale, with the first factor explained 77% of the total variance. The estimated MDC was 15 points. We provided an example of functional staging application. Conclusion Results supported sound psychometric properties and clinical usage of the ABC Scale for older adults seeking outpatient rehabilitation therapy. Level of Evidence 2c. J Orthop Sports Phys Ther, Epub 30 Mar 2018. doi:10.2519/jospt.2018.8023.

Vipsi ABC Grupp teatas kavatsusest börsile minna / Anne Oja

Index Scriptorium Estoniae

Oja, Anne, 1970-

2010-01-01

Kaubanduskontsern ABC Grupp maksis tagasi 97,2 mln. krooni eest võlakirju, juhatuse esimehe teatel kasutab ettevõtte meeskond saadud kogemusi naasmaks tulevikus avaliku ettevõtte staatusesse juba aktsiaemitendina

Fifth joint meeting of the American Urological Association and the Japanese Urological Association International Affiliate Society Meeting at the 105th Annual Meeting of the American Urological Association.

Science.gov (United States)

Myers, Robert P; Seki, Narihito; Gotoh, Momokazu; Chai, Toby C; Kaplan, Steven A; Inoue, Keiji; Trachtenberg, John; Kikuchi, Eiji; Nishiyama, Hiroyuki; Chang, Sam S; Lee, Cheryl; Muto, Satoru; Ito, Kazuto; Andriole, Gerald L; Eto, Masatoshi; Sumitomo, Makoto; Kamba, Tomomi; Wood, Chrsitopher G; Margulis, Vitaly; Naito, Seiji; Egawa, Shin

2010-08-01

We are heartily grateful for the warm support of all of the people concerned, including the moderators and panelists of both societies for giving us the opportunity to hold the 5(th) American Urological Association/Japanese Urological Association (AUA/JUA) International Affiliate Society Meeting, held once again at the 105th Annual Meeting of the American Urological Association (29 May-3 June 2010, San Francisco, California, USA). The year of 2010 is a memorable one, being the start of reciprocal collaborations between the AUA and the JUA. The JUA, in collaboration with the AUA, is promoting an academic exchange program whereby outstanding and promising Japanese and American junior faculty members will be given the opportunity to work in the USA and Japan for 1 month. The program not only allows the sharing of knowledge and experience, but also is designed to foster a closer alliance between the AUA and JUA, and assists in identifying future leaders within both organizations. The AUA and JUA will have an exhibit booth at each other's annual meeting, promoting our new joint activities. Both the JUA and AUA will organize educational courses in Hawaii in 2011. With all of these activities, the JUA hopes it will provide greater opportunities for young Japanese urologists to participate in educational projects in the USA. We would like to thank Professor Anton J. Bueschen, President of AUA, Professor Robert C Flanigan, Secretary General of AUA and the staff of the AUA and JUA for supporting our program. At the same time, we need the support of all the members and their valuable suggestions. We look forward to further participation of AUA members to this meeting. Seiji Naito md, President of JUA Shin Egawa md, Chairman of the International Committee of JUA.

My Kind of Town (Chicago Is): Content Collections Optimize Learning Related to the 2018 AANA Annual Meeting.

Science.gov (United States)

Hunt, Timothy J; Brand, Jefferson C; Rossi, Michael J; Lubowitz, James H

2018-04-01

The 2018 Arthroscopy Association of North America Annual Meeting represents an opportunity to deepen one's understanding of a wide variety of topics. Arthroscopy journal readers have diverse practices and interests, and the meeting is designed to accommodate individual needs. The constructivist learning theory provides that scholars learn in many different ways. Thus, to enrich your learning experience, selected recently published Arthroscopy articles are suggested to supplement material presented at the meeting. The articles are collated on our web site in Content Collections, to allow meeting participants to prepare and to allow those unable to attend to remain engaged. We offer suggestions and encourage readers to customize their own learning experience. Copyright © 2018 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

Phase behavior of model ABC triblock copolymers

Science.gov (United States)

Chatterjee, Joon

The phase behavior of poly(isoprene-b-styrene- b-ethylene oxide) (ISO), a model ABC triblock copolymer has been studied. This class of materials exhibit self-assembly, forming a large array of ordered morphologies at length scales of 5-100 nm. The formation of stable three-dimensionally continuous network morphologies is of special interest in this study. Since these nanostructures considerably impact the material properties, fundamental knowledge for designing ABC systems have high technological importance for realizing applications in the areas of nanofabrication, nanoporous media, separation membranes, drug delivery and high surface area catalysts. A comprehensive framework was developed to describe the phase behavior of the ISO triblock copolymers at weak to intermediate segregation strengths spanning a wide range of composition. Phases were characterized through a combination of characterization techniques, including small angle x-ray scattering, dynamic mechanical spectroscopy, transmission electron microscopy, and birefringence measurements. Combined with previous investigations on ISO, six different stable ordered state symmetries have been identified: lamellae (LAM), Fddd orthorhombic network (O70), double gyroid (Q230), alternating gyroid (Q214), hexagonal (HEX), and body-centered cubic (BCC). The phase map was found to be somewhat asymmetric around the fI = fO isopleth. This work provides a guide for theoretical studies and gives insight into the intricate effects of various parameters on the self-assembly of ABC triblock copolymers. Experimental SAXS data evaluated with a simple scattering intensity model show that local mixing varies continuously across the phase map between states of two- and three-domain segregation. Strategies of blending homopolymers with ISO triblock copolymer were employed for studying the swelling properties of a lamellar state. Results demonstrate that lamellar domains swell or shrink depending upon the type of homopolymer that

3rd Annual Earth System Grid Federation and 3rd Annual Earth System Grid Federation and Ultrascale Visualization Climate Data Analysis Tools Face-to-Face Meeting Report December 2013

Energy Technology Data Exchange (ETDEWEB)

Williams, Dean N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2014-02-21

The climate and weather data science community gathered December 3–5, 2013, at Lawrence Livermore National Laboratory, in Livermore, California, for the third annual Earth System Grid Federation (ESGF) and Ultra-scale Visualization Climate Data Analysis Tools (UV-CDAT) Face-to-Face (F2F) Meeting, which was hosted by the Department of Energy, National Aeronautics and Space Administration, National Oceanic and Atmospheric Administration, the European Infrastructure for the European Network of Earth System Modelling, and the Australian Department of Education. Both ESGF and UV-CDAT are global collaborations designed to develop a new generation of open-source software infrastructure that provides distributed access and analysis to observed and simulated data from the climate and weather communities. The tools and infrastructure developed under these international multi-agency collaborations are critical to understanding extreme weather conditions and long-term climate change, while the F2F meetings help to build a stronger climate and weather data science community and stronger federated software infrastructure. The 2013 F2F meeting determined requirements for existing and impending national and international community projects; enhancements needed for data distribution, analysis, and visualization infrastructure; and standards and resources needed for better collaborations.

From bench to bedside: successful translational nanomedicine: highlights of the Third Annual Meeting of the American Academy of Nanomedicine.

Science.gov (United States)

Wei, Chiming; Liu, Nanhai; Xu, Pingyi; Heller, Mike; Tomalia, Donald A; Haynie, Donald T; Chang, Esther H; Wang, Kuan; Lee, Yoon-Sik; Lyubchenko, Yuri L; Bawa, Raj; Tian, Ryan; Hanes, Justin; Pun, Suzie; Meiners, Jens-Christian; Guo, Peixuan

2007-12-01

The Third Annual Meeting of the American Academy of Nanomedicine (AANM) was held at the University of California San Diego, in San Diego, California during September 7-8, 2007. The meeting was focused on successful translational nanomedicine: from bench to bedside. There were four keynote lectures and eight scientific symposiums in this meeting. The researchers and investigators reported the results and process of current nanomedicine research and approaches to clinical applications. The meeting provided exciting information for nanomedicine clinical-related researches and strategy for further development of nanomedicine research which will be benefits to clinical practice.

Effect of SOS-induced levels of imuABC on spontaneous and damage-induced mutagenesis in Caulobacter crescentus.

Science.gov (United States)

Alves, Ingrid R; Lima-Noronha, Marco A; Silva, Larissa G; Fernández-Silva, Frank S; Freitas, Aline Luiza D; Marques, Marilis V; Galhardo, Rodrigo S

2017-11-01

imuABC (imuAB dnaE2) genes are responsible for SOS-mutagenesis in Caulobacter crescentus and other bacterial species devoid of umuDC. In this work, we have constructed operator-constitutive mutants of the imuABC operon. We used this genetic tool to investigate the effect of SOS-induced levels of these genes upon both spontaneous and damage-induced mutagenesis. We showed that constitutive expression of imuABC does not increase spontaneous or damage-induced mutagenesis, nor increases cellular resistance to DNA-damaging agents. Nevertheless, the presence of the operator-constitutive mutation rescues mutagenesis in a recA background, indicating that imuABC are the only genes required at SOS-induced levels for translesion synthesis (TLS) in C. crescentus. Furthermore, these data also show that TLS mediated by ImuABC does not require RecA, unlike umuDC-dependent mutagenesis in E. coli. Copyright © 2017 Elsevier B.V. All rights reserved.

77 FR 14351 - New England Fishery Management Council; Public Meeting

Science.gov (United States)

2012-03-09

... assessments and develop ABC recommendations for the Council for redfish, Georges Bank haddock, Gulf of Maine/Georges Bank windowpane flounder, Southern New England/Mid-Atlantic windowpane flounder, ocean pout... address the emergency. Special Accommodations This meeting is physically accessible to people with...

A2e High Fidelity Modeling: Strategic Planning Meetings

Energy Technology Data Exchange (ETDEWEB)

Hammond, Steven W. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Sprague, Michael A. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Womble, David [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Barone, Matt [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2015-11-01

Atmosphere to electrons (A2e) is a multi-year U.S. Department of Energy (DOE) research initiative targeting significant reductions in the cost of wind energy through an improved understanding of the complex physics governing wind flow into and through whole wind farms. Better insight into the flow physics of large multi-turbine arrays will address the plant-level energy losses, is likely to reduce annual operational costs by hundreds of millions of dollars, and will improve project financing terms to more closely resemble traditional capital projects. In support of this initiative, two planning meetings were convened, bringing together professionals from universities, national laboratories, and industry to discuss wind plant modeling challenges, requirements, best practices, and priorities. This report documents the combined work of the two meetings and serves as a key part of the foundation for the A2e/HFM effort for predictive modeling of whole wind plant physics.

ATP-binding cassette (ABC) transporters in normal and pathological lung

NARCIS (Netherlands)

van der Deen, M; de Vries, EGE; Timens, W; Scheper, RJ; Timmer-Bosscha, H; Postma, DS

2005-01-01

ATP-binding cassette ( ABC) transporters are a family of transmembrane proteins that can transport a wide variety of substrates across biological membranes in an energy-dependent manner. Many ABC transporters such as P-glycoprotein ( P-gp), multidrug resistance-associated protein 1 ( MRP1) and

English Book Club - Annual General Meeting

CERN Multimedia

2012-01-01

Wednesday 16 January at 5.30 p.m. In the Clubs barracks by entrance A, CERN building 564. Agenda: 1/ Election of the Chairman of the Meeting 2/ President’s report on 2012 Activities 3/ Treasurer's Report 4/ Nomination for renewal of committee members for 2013 5/ Any Other Business

Prevalence of symptom control and palliative care abstracts presented at the Annual Meeting of the American Society for Therapeutic Radiology and Oncology

International Nuclear Information System (INIS)

Barnes, Elizabeth A.; Palmer, J. Lynn; Bruera, Eduardo

2002-01-01

Purpose: Forty percent of all patients referred for radiotherapy are treated with palliative intent. The American Society for Therapeutic Radiology and Oncology (ASTRO) has recently emphasized the importance of radiation oncologists being skilled in the field of symptom control and palliative care (SCPC). The purpose of this study was to determine the number of abstracts relating to SCPC presented at the annual ASTRO meetings. Methods and Materials: The number of SCPC abstracts presented at ASTRO meetings between 1993 and 2000 was counted. Abstracts were included if they described populations with advanced or metastatic cancer for whom the goal of treatment was symptom palliation. The treatment sites and symptoms palliated were recorded. Results: Of 3511 abstracts presented at ASTRO between 1993 and 2000, an average of 47 (1.3%, range 0.9-2.2%/y) were related to SCPC. The most common treatment sites were bone, brain, and lung. Pain, bleeding, and neurologic and pulmonary symptoms were the ones most commonly palliated. Thirty-two percent of the SCPC abstracts involved randomized controlled trials, 47% had palliation of symptoms as a secondary treatment outcome, and in 21%, the symptomatic treatment outcome was not specifically stated. Conclusion: SCPC research has been poorly represented at the annual ASTRO meetings. Education and research in this field needs to be actively encouraged, because SCPC is an important component of a radiation oncologist's role in comprehensive patient care

A Neisseria meningitidis fbpABC mutant is incapable of using nonheme iron for growth.

Science.gov (United States)

Khun, H H; Kirby, S D; Lee, B C

1998-05-01

The neisserial fbpABC locus has been proposed to act as an iron-specific ABC transporter system. To confirm this assigned function, we constructed an fbpABC mutant in Neisseria meningitidis by insertional inactivation of fbpABC with a selectable antibiotic marker. The mutant was unable to use iron supplied from human transferrin, human lactoferrin, or iron chelates. However, the use of iron from heme and human hemoglobin was unimpaired. These results support the obligatory participation of fbpABC in neisserial periplasmic iron transport and do not indicate a role for this genetic locus in the heme iron pathway.

Implementation of the ABC Model in a Company Dealing with Extraction of Raw Materials

Directory of Open Access Journals (Sweden)

Radoslav Bajus

2014-06-01

Full Text Available ABC method is a new system for accurate product pricing, cost analysis of the causes of individual products and their optimization. The prices of products are accurately taken into account according to all relevant overhead costs in their actual context and relationships. Except of product costs, ABC method follows costs regarding customers, suppliers, distribution, transport, manufacturing, operational and security processes, management processes and other business activities. ABC method sees the company as a complex of interrelated activities and processes. ABC method represents more precise cost calculation for the product. The aim of the present article is to highlight the introduction of the ABC method to the enterprise and compare it with the traditional method. The result is to reduce costs by introducing ABC method to the enterprise.

Profiling of ABC transporters ABCB5, ABCF2 and nestin-positive stem cells in nevi, in situ and invasive melanoma.

Science.gov (United States)

Setia, Namrata; Abbas, Ossama; Sousa, Yessica; Garb, Jane L; Mahalingam, Meera

2012-08-01

Distinct ABCB5 forms and ABCF2, members of the ATP-binding cassette (ABC) superfamily of transporters, are normally expressed in various tissues and cells, and enhanced expression of both has been demonstrated in select cancers. In melanoma cell lines, gene expression profiling of ABC transporters has revealed enhanced expression of melanocyte-specific ABCB5 and ABCF2 proteins. Given this, our primary aim was to ascertain immunohistochemical expression of the ABC transporters ABCB5 and ABCF2 and, the stem cell marker, nestin in a spectrum of benign and malignant nevomelanocytic proliferations, including nevi (n=30), in situ (n=31) and invasive (n=24) primary cutaneous melanomas to assess their role in the stepwise development of malignancy. In addition, their expression was compared with established melanoma prognosticators to ascertain their utility as independent prognosticators. A semiquantitative scoring system was utilized by deriving a cumulative score (based on percentage positivity cells and intensity of expression) and statistical analyses was carried out using analysis of variance with linear contrasts. Mean cumulative score in nevi, in situ and invasive melanoma were as follows: 3.8, 4.4 and 5.3 for ABCB5, respectively (P1, after controlling for the presence of ulceration and mitotic activity, the expression of both proteins did not significantly correlate with known melanoma prognosticators. The gradual increase in the expression of ABCB5 from benign nevus to in situ to invasive melanoma suggests that it plays a role in melanomagenesis. On the basis of our findings, a prospective study with follow-up data is required to ascertain the utility of ABCB5 as a therapeutic target.

Genome-wide analysis of the ATP-binding cassette (ABC) transporter gene family in sea lamprey and Japanese lamprey.

Science.gov (United States)

Ren, Jianfeng; Chung-Davidson, Yu-Wen; Yeh, Chu-Yin; Scott, Camille; Brown, Titus; Li, Weiming

2015-06-06

Lampreys are extant representatives of the jawless vertebrate lineage that diverged from jawed vertebrates around 500 million years ago. Lamprey genomes contain information crucial for understanding the evolution of gene families in vertebrates. The ATP-binding cassette (ABC) gene family is found from prokaryotes to eukaryotes. The recent availability of two lamprey draft genomes from sea lamprey Petromyzon marinus and Japanese lamprey Lethenteron japonicum presents an opportunity to infer early evolutionary events of ABC genes in vertebrates. We conducted a genome-wide survey of the ABC gene family in two lamprey draft genomes. A total of 37 ABC transporters were identified and classified into seven subfamilies; namely seven ABCA genes, 10 ABCB genes, 10 ABCC genes, three ABCD genes, one ABCE gene, three ABCF genes, and three ABCG genes. The ABCA subfamily has expanded from three genes in sea squirts, seven and nine in lampreys and zebrafish, to 13 and 16 in human and mouse. Conversely, the multiple copies of ABCB1-, ABCG1-, and ABCG2-like genes found in sea squirts have contracted in the other species examined. ABCB2 and ABCB3 seem to be new additions in gnathostomes (not in sea squirts or lampreys), which coincides with the emergence of the gnathostome-specific adaptive immune system. All the genes in the ABCD, ABCE and ABCF subfamilies were conserved and had undergone limited duplication and loss events. In the sea lamprey transcriptomes, the ABCE and ABCF gene subfamilies were ubiquitously and highly expressed in all tissues while the members in other gene subfamilies were differentially expressed. Thirteen more lamprey ABC transporter genes were identified in this study compared with a previous study. By concatenating the same gene sequences from the two lampreys, more full length sequences were obtained, which significantly improved both the assignment of gene names and the phylogenetic trees compared with a previous analysis using partial sequences. The ABC

abc: The AspectBench Compiler for AspectJ

DEFF Research Database (Denmark)

Allan, Chris; Avgustinov, Pavel; Christensen, Aske Simon

2005-01-01

abc is an extensible, optimising compiler for AspectJ. It has been designed as a workbench for experimental research in aspect-oriented programming languages and compilers. We outline a programme of research in these areas, and we review how abc can help in achieving those research goals...

47{sup th} Annual meeting on nuclear technology (AMNT 2016). Key topic / Enhanced safety and operation excellence

Energy Technology Data Exchange (ETDEWEB)

Traichel, Anke [NUKEM Technologies Engineering Services GmbH, Alzenau (Germany). Dept. of Safety Engineering and Assessment / Proposals Engineering

2017-04-15

Summary report on the Key Topic ''Enhanced Safety and Operation Excellence'' Technical Session ''Safety, IT, Hazards and PSA'' of the 47th Annual Meeting on Nuclear Technology (AMNT 2016) held in Hamburg, 10 to 12 May 2016.

From abstract to publication: the fate of research presented at an annual forensic meeting.

Science.gov (United States)

Tambuscio, Silvia; Boghossian, Elie; Sauvageau, Anny

2010-11-01

In forensic sciences, the fate of abstracts presented at international meetings has not yet been assessed. The purpose of this study is to estimate publication ratio and evaluate possible predictors of publication after the 58th edition of the 2006 American Academy of Forensic Sciences annual meeting. Section of the meeting, type of presentation (oral platform or poster), number of authors per abstract and per paper, time span to publication, countries involved, and journal of publication were tabulated. A total of 623 abstracts were presented, from which 102 were subsequently published as a full paper. The overall publication rate was 16.4%, ranging from 3.4% (jurisprudence) to 28.8% (toxicology). The type of presentation (oral platform or poster) did not significantly affect the outcome of the abstract. However, a higher number of authors, foreign authors, and international collaboration were found to be good predictive factors of publication. © 2010 American Academy of Forensic Sciences.

78 FR 43146 - Gulf of Mexico Fishery Management Council; Public Meeting

Science.gov (United States)

2013-07-19

... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration RIN 0648-XC763 Gulf of Mexico Fishery Management Council; Public Meeting AGENCY: National Marine Fisheries Service (NMFS... d. Recommendation of ABC 4. Overview of ongoing Coastal Migratory Pelagics Amendments a. CMP...

77 FR 39998 - Mid-Atlantic Fishery Management Council; Public Meetings

Science.gov (United States)

2012-07-06

... Statistical Committee (SSC) and the Bluefish, Summer Flounder, Scup, and Black Sea Bass Monitoring Committees.... In addition, a meeting of the Council Monitoring Committees for bluefish, summer flounder, scup, and... and bluefish; review and adopt criteria for establishing multi-year ABC recommendations; develop 2013...

ANALISIS BEBAN KERJA DENGAN MENGGUNAKAN METODE CVL DAN NASATLX DI PT. ABC

Directory of Open Access Journals (Sweden)

Renty Anugerah Mahaji Puteri

2017-10-01

Full Text Available PT. ABC merupakan perusahaan Jepang yang bergerak di bidang usaha jasa konstruksi mekanikal, elektrikal, dan system komunikasi. Sebagai perusahaan jasa konstruksi, PT. ABC dituntut untuk mencapai tujuan / target perusahaan tiap tahunnya yaitu mendapatkan tender proyek, maka tak jarang karyawannya dituntut untuk lembur. Seringnya karyawan lembur, maka menimbulkan masalah kelelahan terhadap para karyawannya sehingga target tidak tercapai. Penelitian ini bertujuan untuk mengevaluasi beban kerja yang dialami oleh engineer leader pada Departemen DesaindanOperasional di PT. ABC. Beban kerja yang diukur adalah beban kerja fisik dan mental. Beban kerja fisik diukur berdasarkan cardiovascular load (CVL. Beban kerja mental diukur dengan menggunakan metode NASA-Task Load Index (NASA-TLX. Berdasarkan hasil analisis CVL, beban kerja fisik yang diterima engineer proyek memiliki presentase CVL sebesar 31,16%, denganhasilperbaikanmenjadi 23,38%. Sedangkan dari hasil analisis NASA-TLX, beban kerja mental yang diterima engineer proyek yaitu dengan skor NASA-TLX 74,2% denganhasilperbaikanmenjadi 51,6%, sedangkan skor NASA-TLX engineer head office 61,5% denganhasilperbaikanmenjadi 47,66%.

29 CFR 2701.2 - Open meetings policy; closure of meetings.

Science.gov (United States)

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Open meetings policy; closure of meetings. 2701.2 Section... GOVERNMENT IN THE SUNSHINE ACT REGULATIONS § 2701.2 Open meetings policy; closure of meetings. (a) Policy. Commission meetings will generally be open to public observation, including meetings concerning the...

Evidence for an ABC-Type Riboflavin Transporter System in Pathogenic Spirochetes

Science.gov (United States)

Deka, Ranjit K.; Brautigam, Chad A.; Biddy, Brent A.; Liu, Wei Z.; Norgard, Michael V.

2013-01-01

ABSTRACT Bacterial transporter proteins are involved in the translocation of many essential nutrients and metabolites. However, many of these key bacterial transport systems remain to be identified, including those involved in the transport of riboflavin (vitamin B2). Pathogenic spirochetes lack riboflavin biosynthetic pathways, implying reliance on obtaining riboflavin from their hosts. Using structural and functional characterizations of possible ligand-binding components, we have identified an ABC-type riboflavin transport system within pathogenic spirochetes. The putative lipoprotein ligand-binding components of these systems from three different spirochetes were cloned, hyperexpressed in Escherichia coli, and purified to homogeneity. Solutions of all three of the purified recombinant proteins were bright yellow. UV-visible spectra demonstrated that these proteins were likely flavoproteins; electrospray ionization mass spectrometry and thin-layer chromatography confirmed that they contained riboflavin. A 1.3-Å crystal structure of the protein (TP0298) encoded by Treponema pallidum, the syphilis spirochete, demonstrated that the protein’s fold is similar to the ligand-binding components of ABC-type transporters. The structure also revealed other salient details of the riboflavin binding site. Comparative bioinformatics analyses of spirochetal genomes, coupled with experimental validation, facilitated the discovery of this new ABC-type riboflavin transport system(s). We denote the ligand-binding component as riboflavin uptake transporter A (RfuA). Taken together, it appears that pathogenic spirochetes have evolved an ABC-type transport system (RfuABCD) for survival in their host environments, particularly that of the human host. PMID:23404400

Tenth annual meeting, Vienna, Austria, 29 March - 1 April 1977. Summary report. Part III

Energy Technology Data Exchange (ETDEWEB)

NONE

1977-11-01

The Summary Report - Part III of the Tenth Annual Meeting of the IAEA International Working Group on Fast Reactors - contains the discussions on the commercial development of FBRs according to national plans, mostly related to technology problems of containment design, fuel fabrication, fuel failures, sodium pressure, fuel-sodium interaction, computer codes needed for licensing. Most of the discussions were related to the existing reactors: BN-600, BN-350, BN-1600, BOR-60, RAPSODIE, PHENIX.

Tenth annual meeting, Vienna, Austria, 29 March - 1 April 1977. Summary report. Part III

International Nuclear Information System (INIS)

1977-11-01

The Summary Report - Part III of the Tenth Annual Meeting of the IAEA International Working Group on Fast Reactors - contains the discussions on the commercial development of FBRs according to national plans, mostly related to technology problems of containment design, fuel fabrication, fuel failures, sodium pressure, fuel-sodium interaction, computer codes needed for licensing. Most of the discussions were related to the existing reactors: BN-600, BN-350, BN-1600, BOR-60, RAPSODIE, PHENIX

Patient Participation in Psoriasis and Psoriatic Arthritis Outcome Research: A Report from the GRAPPA 2013 Annual Meeting

NARCIS (Netherlands)

de Wit, M.P.T.; Campbell, W.; Fitzgerald, O.; Gladman, D.D.; Helliwell, P.S.; James, J.; Lindsay, C.; MacDonald, R.; McHugh, N.J.; Mease, P.J.; Orbai, A.M.; Palominos, P.; Parkinson, A.; Tillett, W.; Goel, N.

2014-01-01

For the first time, 8 patients with psoriatic arthritis (PsA) participated as full delegates at the 2013 Annual Meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA). Patients were invited to provide their perspective for different sessions of the conference

British Society of Neuroradiologists, annual meeting, Hilton National Hotel, Stansted Airport, Essex, UK, 8-9 October 1993. Abstracts

International Nuclear Information System (INIS)

Anon.

1994-01-01

Eighteen abstracts of scientific papers are presented which were read at the Annual Meeting of the British Society of Neuroradiologists, held in Essex from 8-9 October 1993, dealing with the diagnostic evaluation of a variety of brain diseases. (orig.)

SU-E-T-401: Feasibility Study of Using ABC to Gate Lung SBRT Treatment

International Nuclear Information System (INIS)

Cao, D; Xie, X; Shepard, D

2014-01-01

Purpose: The current SBRT treatment techniques include free breathing (FB) SBRT and gated FB SBRT. Gated FB SBRT has smaller target and less lung toxicity with longer treatment time. The recent development of direct connectivity between the ABC and linac allowing for automated beam gating. In this study, we have examined the feasibility of using ABC system to gate the lung SBRT treatment. Methods: A CIRS lung phantom with a 3cm sphere-insert and a moving chest plate was used in this study. Sinusoidal motion was used for the FB pattern. An ABC signal was imported to simulate breath holds. 4D-CT was taken in FB mode and average-intensity-projection (AIP) was used to create FB and 50% gated FB SBRT planning CT. A manually gated 3D CT scan was acquired for ABC gated SBRT planning.An SBRT plan was created for each treatment option. A surface-mapping system was used for 50% gating and ABC system was used for ABC gating. A manually gated CBCT scan was also performed to verify setup. Results: Among three options, the ABC gated plan has the smallest PTV of 35.94cc, which is 35% smaller comparing to that of the FB plan. Consequently, the V20 of the left lung reduced by 15% and 23% comparing to the 50% gated FB and FB plans, respectively. The FB plan took 4.7 minutes to deliver, while the 50% gated FB plan took 18.5 minutes. The ABC gated plan delivery took only 10.6 minutes. A stationary target with 3cm diameter was also obtained from the manually gated CBCT scan. Conclusion: A strategy for ABC gated lung SBRT was developed. ABC gating can significantly reduce the lung toxicity while maintaining the target coverage. Comparing to the 50% gated FB SBRT, ABC gated treatment can also provide less lung toxicity as well as improved delivery efficiency. This research is funded by Elekta

Creating an iPhone Application for Collecting Continuous ABC Data

Science.gov (United States)

Whiting, Seth W.; Dixon, Mark R.

2012-01-01

This paper provides an overview and task analysis for creating a continuous ABC data- collection application using Xcode on a Mac computer. Behavior analysts can program an ABC data collection system, complete with a customized list of target clients, antecedents, behaviors, and consequences to be recorded, and have the data automatically sent to…

48{sup th} Annual meeting on nuclear technology (AMNT). Key topic / Outstanding know-how and sustainable innovations

Energy Technology Data Exchange (ETDEWEB)

Raetzke, Christian [CONLAR - Consulting on Nuclear Law, Licensing and Regulation, Leipzig (Germany)

2017-08-15

Summary report on the Key Topic Outstanding Know-How and Sustainable Innovations, Focus Session: International Regulation: Leveraging the Experience of Established Nuclear Countries for Regulations and Projects in Newcomer Countries, of the 48th Annual Meeting on Nuclear Technology (AMNT 2017) held in Berlin, 16 to 17 May 2017.

Are P values and statistical assessments in poster abstracts presented at annual meetings of Taiwan Society of Anesthesiologists relative to the characteristics of hospitals?

Science.gov (United States)

Lee, Fu-Jung; Wu, Chih-Cheng; Peng, Shih-Yen; Fan, Kuo-Tung

2007-09-01

Many anesthesiologists in medical centers (MC) or in anesthesiologist-training hospitals (ATH) are accustomed to present their research data in the form of poster abstracts at the annual meetings of Taiwan Society of Anesthesiologists (TSA) to represent their academic gainings in a designated period of time. However, an orphaned P value without mentioning the related specified statistical test has frequently been found in these articles. The difference in presentation of statistical test after P value between MC/ATH and non-MC/non-ATH in recent three TSA consecutive annual meetings was explored in this article. We collected the proceedings handbooks of TSA annual meetings in a period spanning 3 yrs (2003 to 2005) and analyzed the hospital characteristic of first institute-byliner in the poster abstract. Data were analyzed with Fisher's exact test and statistical significance was assumed if P poster abstracts with byliners of 20 hospitals. Only 2 of the 20 hospitals were accredited as non-ATH and 4 as non-MC. There were 64 (63%) abstracts without specified statistical test after P value and no significant difference was found among each category. (P = 0.47 in ATH vs. non-ATH and P = 0.07 in MC vs. non-MC). The basic concept of P value with specified statistical test was not applicable comprehensively in poster abstracts of the annual conferences. Based on our wishful intention, we suggest that the anesthesia administrators and senior anesthesiologists at ATH or MC, and the members of the committee responsible for running academic affairs in TSA, should pay attention to this prodigy and work together to improve our basic statistics in poster presentation.

[Treatment of lumbar intervertebral disc displacement with chondroitinase ABC--experimental basis for clinical application].

Science.gov (United States)

Takahashi, Toyomi

2004-07-01

After single intradiscal injection of C-ABC in rabbit inter-vertebral discs, water content in the matrix of nucleus pulposus diminished clearly. After similar injection of C-ABC in sheep discs, disc inner pressure was diminished. After single intradiscal injection of C-ABC in dog inter-vertebral discs suffering disc herniation, the syndromes coming from the herniation diminished or disappeared. Based on these observations C-ABC is expected to be a chemonucleolytic agent and a human clinical trial is now in progress.

The ABC gene family in arthropods: comparative genomics and role in insecticide transport and resistance.

Science.gov (United States)

Dermauw, Wannes; Van Leeuwen, Thomas

2014-02-01

About a 100 years ago, the Drosophila white mutant marked the birth of Drosophila genetics. The white gene turned out to encode the first well studied ABC transporter in arthropods. The ABC gene family is now recognized as one of the largest transporter families in all kingdoms of life. The majority of ABC proteins function as primary-active transporters that bind and hydrolyze ATP while transporting a large diversity of substrates across lipid membranes. Although extremely well studied in vertebrates for their role in drug resistance, less is known about the role of this family in the transport of endogenous and exogenous substances in arthropods. The ABC families of five insect species, a crustacean and a chelicerate have been annotated in some detail. We conducted a thorough phylogenetic analysis of the seven arthropod and human ABC protein subfamilies, to infer orthologous relationships that might suggest conserved function. Most orthologous relationships were found in the ABCB half transporter, ABCD, ABCE and ABCF subfamilies, but specific expansions within species and lineages are frequently observed and discussed. We next surveyed the role of ABC transporters in the transport of xenobiotics/plant allelochemicals and their involvement in insecticide resistance. The involvement of ABC transporters in xenobiotic resistance in arthropods is historically not well documented, but an increasing number of studies using unbiased differential gene expression analysis now points to their importance. We give an overview of methods that can be used to link ABC transporters to resistance. ABC proteins have also recently been implicated in the mode of action and resistance to Bt toxins in Lepidoptera. Given the enormous interest in Bt toxicology in transgenic crops, such findings will provide an impetus to further reveal the role of ABC transporters in arthropods. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

Anger and the ABC model underlying Rational-Emotive Behavior Therapy.

Science.gov (United States)

Ziegler, Daniel J; Smith, Phillip N

2004-06-01

The ABC model underlying Ellis's Rational-Emotive Behavior Therapy predicts that people who think more irrationally should display greater trait anger than do people who think less irrationally. This study tested this prediction regarding the ABC model. 186 college students were administered the Survey of Personal Beliefs and the State-Trait Anger Expression Inventory-Second Edition to measure irrational thinking and trait anger, respectively. Students who scored higher on Overall Irrational Thinking and Low Frustration Tolerance scored significantly higher on Trait Anger than did those who scored lower on Overall Irrational Thinking and Low Frustration Tolerance. This indicates support for the ABC model, especially Ellis's construct of irrational beliefs which is central to the model.

Brain barriers and functional interfaces with sequential appearance of ABC efflux transporters during human development

DEFF Research Database (Denmark)

Møllgård, Kjeld; Dziegielewska, Katarzyna M.; Holst, Camilla B.

2017-01-01

Adult brain is protected from entry of drugs and toxins by specific mechanisms such as ABC (ATP-binding Cassette) efflux transporters. Little is known when these appear in human brain during development. Cellular distribution of three main ABC transporters (ABCC1, ABCG2, ABCB1) was determined...... at blood-brain barriers and interfaces in human embryos and fetuses in first half of gestation. Antibodies against claudin-5 and-11 and antibodies to α-fetoprotein were used to describe morphological and functional aspects of brain barriers. First exchange interfaces to be established, probably at 4...... three transporters. Results provide evidence for sequential establishment of brain exchange interfaces and spatial and temporal timetable for three main ABC transporters in early human brain....

Genome-wide identification of whole ATP-binding cassette (ABC) transporters in the intertidal copepod Tigriopus japonicus.

Science.gov (United States)

Jeong, Chang-Bum; Kim, Bo-Mi; Lee, Jae-Seong; Rhee, Jae-Sung

2014-08-05

The ATP-binding cassette (ABC) transporter superfamily is one of the largest transporter gene families and is observed in all animal taxa. Although a large set of transcriptomic data was recently assembled for several species of crustaceans, identification and annotation of the large ABC transporter gene family have been very challenging. In the intertidal copepod Tigriopus japonicus, 46 putative ABC transporters were identified using in silico analysis, and their full-length cDNA sequences were characterized. Phylogenetic analysis revealed that the 46 T. japonicus ABC transporters are classified into eight subfamilies (A-H) that include all the members of all ABC subfamilies, consisting of five ABCA, five ABCB, 17 ABCC, three ABCD, one ABCE, three ABCF, seven ABCG, and five ABCH subfamilies. Of them, unique isotypic expansion of two clades of ABCC1 proteins was observed. Real-time RT-PCR-based heatmap analysis revealed that most T. japonicus ABC genes showed temporal transcriptional expression during copepod development. The overall transcriptional profile demonstrated that half of all T. japonicus ABC genes were strongly associated with at least one developmental stage. Of them, transcripts TJ-ABCH_88708 and TJ-ABCE1 were highly expressed during all developmental stages. The whole set of T. japonicus ABC genes and their phylogenetic relationships will provide a better understanding of the comparative evolution of essential gene family resources in arthropods, including the crustacean copepods.

ABC+SCM=Sant?

OpenAIRE

Dahl, Jonas; Porelius, Jesper

2006-01-01

Background: Companies of today commonly search to gain competitive advantages throughout different forms of co-operation, one of which is referred to as Supply Chain Management. Although little research has been assigned to the topic of how to manage and control this type of relation, lately a growing number of academics has been arguing that ABC is an appropriate mean of controlling this type of relationships. Purpose: The purpose of this thesis is to investigate to what degree the ongoing d...

Phylodynamic Inference with Kernel ABC and Its Application to HIV Epidemiology.

Science.gov (United States)

Poon, Art F Y

2015-09-01

The shapes of phylogenetic trees relating virus populations are determined by the adaptation of viruses within each host, and by the transmission of viruses among hosts. Phylodynamic inference attempts to reverse this flow of information, estimating parameters of these processes from the shape of a virus phylogeny reconstructed from a sample of genetic sequences from the epidemic. A key challenge to phylodynamic inference is quantifying the similarity between two trees in an efficient and comprehensive way. In this study, I demonstrate that a new distance measure, based on a subset tree kernel function from computational linguistics, confers a significant improvement over previous measures of tree shape for classifying trees generated under different epidemiological scenarios. Next, I incorporate this kernel-based distance measure into an approximate Bayesian computation (ABC) framework for phylodynamic inference. ABC bypasses the need for an analytical solution of model likelihood, as it only requires the ability to simulate data from the model. I validate this "kernel-ABC" method for phylodynamic inference by estimating parameters from data simulated under a simple epidemiological model. Results indicate that kernel-ABC attained greater accuracy for parameters associated with virus transmission than leading software on the same data sets. Finally, I apply the kernel-ABC framework to study a recent outbreak of a recombinant HIV subtype in China. Kernel-ABC provides a versatile framework for phylodynamic inference because it can fit a broader range of models than methods that rely on the computation of exact likelihoods. © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

Energy Coupling Factor-Type ABC Transporters for Vitamin Uptake in Prokaryotes

NARCIS (Netherlands)

Erkens, Guus B.; Dosz-Majsnerowska, Maria; ter Beek, Josy; Slotboom, Dirk Jan

2012-01-01

Energy coupling factor (ECF) transporters are a subgroup of ATP-binding cassette (ABC) transporters involved in the uptake of vitamins and micronutrients in prokaryotes. In contrast to classical ABC importers, ECF transporters do not make use of water-soluble substrate binding proteins or domains

Asymmetric switching in a homodimeric ABC transporter: a simulation study.

Directory of Open Access Journals (Sweden)

Jussi Aittoniemi

2010-04-01

Full Text Available ABC transporters are a large family of membrane proteins involved in a variety of cellular processes, including multidrug and tumor resistance and ion channel regulation. Advances in the structural and functional understanding of ABC transporters have revealed that hydrolysis at the two canonical nucleotide-binding sites (NBSs is co-operative and non-simultaneous. A conserved core architecture of bacterial and eukaryotic ABC exporters has been established, as exemplified by the crystal structure of the homodimeric multidrug exporter Sav1866. Currently, it is unclear how sequential ATP hydrolysis arises in a symmetric homodimeric transporter, since it implies at least transient asymmetry at the NBSs. We show by molecular dynamics simulation that the initially symmetric structure of Sav1866 readily undergoes asymmetric transitions at its NBSs in a pre-hydrolytic nucleotide configuration. MgATP-binding residues and a network of charged residues at the dimer interface are shown to form a sequence of putative molecular switches that allow ATP hydrolysis only at one NBS. We extend our findings to eukaryotic ABC exporters which often consist of two non-identical half-transporters, frequently with degeneracy substitutions at one of their two NBSs. Interestingly, many residues involved in asymmetric conformational switching in Sav1866 are substituted in degenerate eukaryotic NBS. This finding strengthens recent suggestions that the interplay of a consensus and a degenerate NBS in eukaroytic ABC proteins pre-determines the sequence of hydrolysis at the two NBSs.

In celebration of the 60th anniversary proceedings of the KSME 2005 spring annual meeting

International Nuclear Information System (INIS)

2005-01-01

This proceedings contains articles of 2005 spring annual meeting of the Korean Society of Mechanical Engineers. It was held on May 25-27, 2005 in Busan, Korea. This proceedings are comprised of 21 sessions. The main subject titles of session are as follows: nondestructive evaluation, fatigue evaluation, computation mechanics, CAE design, vibration, instrumentation, fabrication, optimum design, heat exchanger, fluid mechanics, nano fluid, plasma, heat transfer analysis, energy (Yi, J. H.)

The ABCs of Student Engagement

Science.gov (United States)

Parsons, Seth A.; Nuland, Leila Richey; Parsons, Allison Ward

2014-01-01

Student engagement is an important consideration for teachers and administrators because it is explicitly associated with achievement. What the authors call the ABC's of engagement they outline as: Affective engagement, Behavioral engagement, and Cognitive engagement. They also present "Three Things Every Teacher Needs to Know about…

Enhanced expression in vivo of HLA-ABC antigens and beta 2-microglobulin on human lymphoid cells induced by human interferon-alpha in patients with lung cancer. Enhanced expression of class I major histocompatibility antigens prior to treatment

DEFF Research Database (Denmark)

Nissen, Mogens Holst; Plesner, T; Larsen, J K

1985-01-01

than 0.5, respectively) by day-to-day analysis of an untreated healthy control group. An increased expression of both HLA-ABC (mean 55%, P less than 0.0005) and beta 2m (mean 23%, P less than 0.01) was also observed prior to treatment in the lung cancer patients when compared to a group of age matched......The effect of cloned human interferon-alpha (IFN-alpha) on the expression of HLA-ABC antigens (HLA-ABC) and beta 2-microglobulin (beta 2m) on human peripheral lymphoid cells in vivo was studied by cytofluorometry using monoclonal antibodies and fluorescein-labelled rabbit anti-mouse immunoglobulin....... A significant increase in the mean fluorescence intensity of HLA-ABC (median 59%, P less than 0.001) and beta 2m (median 57%, P less than 0.001) on small lymphoid cells was observed 24 h after initiation of IFN-alpha treatment (50 X 10(6) units IFN-alpha/m2 three times a week). The enhanced expression...

Functional analysis of the ATP-binding cassette (ABC) transporter gene family of Tribolium castaneum.

Science.gov (United States)

Broehan, Gunnar; Kroeger, Tobias; Lorenzen, Marcé; Merzendorfer, Hans

2013-01-16

The ATP-binding cassette (ABC) transporters belong to a large superfamily of proteins that have important physiological functions in all living organisms. Most are integral membrane proteins that transport a broad spectrum of substrates across lipid membranes. In insects, ABC transporters are of special interest because of their role in insecticide resistance. We have identified 73 ABC transporter genes in the genome of T. castaneum, which group into eight subfamilies (ABCA-H). This coleopteran ABC family is significantly larger than those reported for insects in other taxonomic groups. Phylogenetic analysis revealed that this increase is due to gene expansion within a single clade of subfamily ABCC. We performed an RNA interference (RNAi) screen to study the function of ABC transporters during development. In ten cases, injection of double-stranded RNA (dsRNA) into larvae caused developmental phenotypes, which included growth arrest and localized melanization, eye pigmentation defects, abnormal cuticle formation, egg-laying and egg-hatching defects, and mortality due to abortive molting and desiccation. Some of the ABC transporters we studied in closer detail to examine their role in lipid, ecdysteroid and eye pigment transport. The results from our study provide new insights into the physiological function of ABC transporters in T. castaneum, and may help to establish new target sites for insect control.

Abstracts of the Atlantic Geoscience Society's 2007 colloquium and annual general meeting

International Nuclear Information System (INIS)

Johnson, S.; Parkhill, M.; Wilson, R.; Desrosiers, M.; Lentz, D.; Pitre, C.; Pronk, T.; Spooner, I.; Toole, R.; Wallace, P.

2007-01-01

The Atlantic Geoscience Society (AGS) hosts annual meetings, workshops and field trips to promote a better understanding of the geology of Atlantic Canada. This colloquium highlighted current research in the Atlantic provinces with special sessions devoted to patterns and geohazards in the North Atlantic; late and post-glacial climate change events in eastern Canada; salt matters; tectonic, thermal and resource aspects of Paleozoic to Mesozoic evaporite basins; mineral resources research by students of the Society of Economic Geologists; dendrochronology; a physical volcanology workshop; and, a North American soil geochemical landscape project orientation session. One of the 74 papers presented at this colloquium has been catalogued separately for inclusion in this database

Proceedings of the seventh annual participants' information meeting. DOE Low-Level Waste Management Program

International Nuclear Information System (INIS)

1986-02-01

The Seventh Annual Department of Energy (DOE) Low-Level Waste Management Program (LLWMP) Participants' Information Meeting was held September 10-13, 1985 in Las Vegas, Nevada. The purpose of the meeting was to provide a forum for exchange of information on low-level radioactive waste management activities, requirements, and plans. Attendees included representatives from the DOE Nuclear Energy and Defense Low-Level Waste Management Programs, interim operations offices and their contractor operators; representatives from the US Nuclear Regulatory Commission, US Environmental Protection Agency, US Geological Survey, and their contractors; representatives of states and regions responsible for development of new commercial low-level waste disposal facilities; representatives of Great Britain, France, and Canada; representatives of utilities, private contractors, and parties concerned with low-level waste management issues. The meeting was organized by topical areas to allow for the exchange of information and the promotion of discussion on specific aspects of low-level waste management. Plenary sessions were held at the start and conclusion of the meeting while seven concurrent topical sessions were held during the intervening day and a half. Session chairmen from each of these concurrent sessions presented a summary of the discussion and conclusions resulting from their respective sessions at the final plenary session

Islet cell research brings hope for a diabetes cure: meeting report from the 6(th) annual islet society meeting in Stellenbosch, South Africa.

Science.gov (United States)

Tchokonte-Nana, V; Cockburn, I L; Manda, J K; Kotze, P C; Johnson, J D

2014-01-01

The International Diabetes Federation predicts that, over the next twenty years, the largest increase in the prevalence of diabetes will be in the Africa region. Recognizing an unmet need for more focus on Africa and engagement with African scholars, the Islet Society held its 6th annual meeting July 20-21, 2014 in Stellenbosch, South Africa. Here, we present a report that covers the presentations and discussion points from that meeting. Work was presented on a variety of topics and included presentations by a significant proportion of Africa diabetes researchers. Overall, it was an excellent conference, with many new international collaborations initiated. We hope that other groups will also respond to the need for more conferences in Africa and focused on Africa.

Parents' Perspectives on Braille Literacy: Results from the ABC Braille Study

Science.gov (United States)

Kamei-Hannan, Cheryl; Sacks, Sharon Zell

2012-01-01

Introduction: Parents who were the primary caretakers of children in the Alphabetic and Contracted Braille Study (ABC Braille Study) revealed their perspectives about braille literacy. Methods: A 30-item questionnaire was constructed by the ABC Braille research team, and researchers conducted telephone interviews with 31 parents who were the…

51st Annual Meeting

Indian Academy of Sciences (India)

1966, (a brief account of the meeting is given in this issue), and which .... was placed on neutrinos which are produced copiously during the ..... new vaccine against hepatitis and his work on filariasis, malaria, intestinal parasites, rheumatoid ...

ABC model and the management of costs

Directory of Open Access Journals (Sweden)

Pravdić Predrag

2016-01-01

Full Text Available When a company has multiple objectives at the same time, they all must be considered and balanced when making any business decisions. Linking the markets, capital and resources so as to thus ensure the highest yield is, In fact, the search for competitive advantage as a basic condition for survival in a market economy. In highly detailed systems based on the management of costs or ABC (activity based costing systems, the cost of activities often result in erroneous evaluation of aggregate costs of the action. Improvements in information technology and monitoring decrease of technology costs enabled the ABC system to become a feasible system calculating costs in many organizations.

ABC-F Proteins Mediate Antibiotic Resistance through Ribosomal Protection.

Science.gov (United States)

Sharkey, Liam K R; Edwards, Thomas A; O'Neill, Alex J

2016-03-22

Members of the ABC-F subfamily of ATP-binding cassette proteins mediate resistance to a broad array of clinically important antibiotic classes that target the ribosome of Gram-positive pathogens. The mechanism by which these proteins act has been a subject of long-standing controversy, with two competing hypotheses each having gained considerable support: antibiotic efflux versus ribosomal protection. Here, we report on studies employing a combination of bacteriological and biochemical techniques to unravel the mechanism of resistance of these proteins, and provide several lines of evidence that together offer clear support to the ribosomal protection hypothesis. Of particular note, we show that addition of purified ABC-F proteins to anin vitrotranslation assay prompts dose-dependent rescue of translation, and demonstrate that such proteins are capable of displacing antibiotic from the ribosomein vitro To our knowledge, these experiments constitute the first direct evidence that ABC-F proteins mediate antibiotic resistance through ribosomal protection.IMPORTANCEAntimicrobial resistance ranks among the greatest threats currently facing human health. Elucidation of the mechanisms by which microorganisms resist the effect of antibiotics is central to understanding the biology of this phenomenon and has the potential to inform the development of new drugs capable of blocking or circumventing resistance. Members of the ABC-F family, which includelsa(A),msr(A),optr(A), andvga(A), collectively yield resistance to a broader range of clinically significant antibiotic classes than any other family of resistance determinants, although their mechanism of action has been controversial since their discovery 25 years ago. Here we present the first direct evidence that proteins of the ABC-F family act to protect the bacterial ribosome from antibiotic-mediated inhibition. Copyright © 2016 Sharkey et al.

Analysis of the Use and Impact of Twitter During American Society of Clinical Oncology Annual Meetings From 2011 to 2016: Focus on Advanced Metrics and User Trends.

Science.gov (United States)

Pemmaraju, Naveen; Thompson, Michael A; Mesa, Ruben A; Desai, Tejas

2017-07-01

The use of social media, in particular Twitter, has substantially increased among health care stakeholders in the field of hematology and oncology, with an especially sharp increase in the use of Twitter during times of major national meetings. The most attended meeting in the oncology field is the ASCO annual meeting. Little is known about the detailed metrics involved in the use, volume, and impact of Twitter during the ASCO annual meeting. We conducted a retrospective review of tweets during the ASCO annual meetings from 2011 to 2016. The total data set encompassed 190,732 tweets from 39,745 authors over six consecutive ASCO meetings from 2011 to 2016 (inclusive). Tweets, all publically available, were collected by Nephrology On-Demand Analytics. The number of individual authors increased from 1,429 during the 2011 ASCO meeting to 15,796 during the 2016 ASCO meeting, an 11-fold increase over the total 5-year period. There was a notable increase in tweets from the 2011 ASCO meeting (n = 7,746) to the 2016 ASCO meeting (n = 72,698), a nine-fold increase during the study period. The most commonly tweeted term or topic changed over time, generally reflecting the breakthroughs of each designated year; these terms were "melanoma" for both the 2011 and 2012 ASCO meetings; "breast cancer" for the 2013 ASCO meeting; "lung cancer" for the 2014 ASCO meeting; and "ImmunOnc" or "immunotherapy/immuno-oncology" for both the 2015 and 2016 ASCO meetings. The use of Twitter among health care stakeholders during the ASCO meeting has markedly increased over time, demonstrating the increasing role of social media in the dissemination of findings at the most highly attended hematology and oncology conference of the year.

47{sup th} Annual meeting on nuclear technology (AMNT 2016). Key Topics / Enhanced safety and operation excellence

Energy Technology Data Exchange (ETDEWEB)

Bohnstedt, Angelika [Karlsruher Institut fuer Technologie (KIT), Eggenstein-Leopoldshafen (Germany). Programm Nukleare Entsorgung, Sicherheit und Strahlenforschung (NUSAFE); Baumann, Erik [AREVA GmbH, Erlangen (Germany). Radiation Protection

2016-12-15

Summary report on the Key Topic 'Enhanced Safety and Operation Excellence' Focus Session 'Radiation Protection' of the 47{sup th} Annual Meeting on Nuclear Technology (AMNT 2016) held in Hamburg, 10 to 12 May 2016. Other Sessions of AMNT 2016 have been and will be covered in further issues of atw.

Nearly Finished Genomes Produced Using Gel Microdroplet Culturing (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

Energy Technology Data Exchange (ETDEWEB)

Fitzsimmons, Michael

2012-06-01

Michael Fitzsimmons from Los Alamos National Laboratory gives a talk titled "Nearly Finished Genomes Produced Using Gel Microdroplet Culturing" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

29 CFR 403.2 - Annual financial report.

Science.gov (United States)

2010-07-01

... 29 Labor 2 2010-07-01 2010-07-01 false Annual financial report. 403.2 Section 403.2 Labor... STANDARDS LABOR ORGANIZATION ANNUAL FINANCIAL REPORTS § 403.2 Annual financial report. (a) Every labor... Standards within 90 days after the end of each of its fiscal years, a financial report signed by its...

2015 Annual Meeting of the Canadian Society for History and Philosophy of Mathematics

CERN Document Server

Landry, Elaine

2016-01-01

This volume contains seventeen papers that were presented at the 2015 Annual Meeting of the Canadian Society for History and Philosophy of Mathematics/La Société Canadienne d’Histoire et de Philosophie des Mathématiques, held in Washington, D.C. In addition to showcasing rigorously reviewed modern scholarship on an interesting variety of general topics in the history and philosophy of mathematics, this meeting also honored the memories of Jacqueline (Jackie) Stedall and Ivor Grattan-Guinness; celebrated the Centennial of the Mathematical Association of America; and considered the importance of mathematical communities in a special session. These themes and many others are explored in these collected papers, which cover subjects such as New evidence that the Latin translation of Euclid’s Elements was based on the Arabic version attributed to al-Ḥajjāj Work done on the arc rampant in the seventeenth century The history of numerical methods for finding roots of nonlinear equations An original play feat...

Status of national programmes on fast reactors 1998/99. 32nd annual meeting. Working material

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-07-01

Over the past 32 years, the IAEA has actively encouraged and advocated international cooperation in fast reactor technology. The present publication contains information on the status of fast reactor development and on worldwide activities in this advanced nuclear power technology during 1998/1999, as reported at the 32. annual meeting of the International Working Group on Fast Reactors. It is intended to provide information regarding the current status of LMFR development in IAEA Member States.

Status of national programmes on fast reactors 1998/99. 32nd annual meeting. Working material

International Nuclear Information System (INIS)

1999-01-01

Over the past 32 years, the IAEA has actively encouraged and advocated international cooperation in fast reactor technology. The present publication contains information on the status of fast reactor development and on worldwide activities in this advanced nuclear power technology during 1998/1999, as reported at the 32. annual meeting of the International Working Group on Fast Reactors. It is intended to provide information regarding the current status of LMFR development in IAEA Member States

The ABCs of particle physics

CERN Document Server

Biron, Lauren

2016-01-01

For lovers of rhymes and anthropomorphic Higgs bosons, Symmetry presents its first published board book, The ABCs of Particle Physics. Use it as an illustrated guide to basic particle- and astrophysics terms, or read it to your infant at bedtime, if you don’t mind their first word being “quark.”

IFPA meeting 2010 workshop report I

DEFF Research Database (Denmark)

Abad, C.; Antczak, D.F.; Carvalho, J.

2011-01-01

Workshops are an important part of the IFPA annual meeting. At IFPA Meeting 2010 there were twelve themed workshops, six of which are summarized in this report. 1. The immunology workshop focused on normal and pathological functions of the maternal immune system in pregnancy. 2. The transport wor...

fbpABC gene cluster in Neisseria meningitidis is transcribed as an operon.

Science.gov (United States)

Khun, H H; Deved, V; Wong, H; Lee, B C

2000-12-01

The neisserial fbpABC locus has been proposed to constitute a single transcriptional unit. To confirm this operonic arrangement, transcription assays using reverse transcriptase PCR amplification were conducted with Neisseria meningitidis. The presence of fbpAB and fbpBC transcripts obtained by priming cDNA synthesis with an fbpC-sequence-specific oligonucleotide indicates that fbpABC is organized as a single expression unit. The ratio of fbpA to fbpABC mRNA was approximately between 10- to 20-fold, as determined by real-time quantitative PCR.

Applying Activity Based Costing (ABC) Method to Calculate Cost Price in Hospital and Remedy Services.

Science.gov (United States)

Rajabi, A; Dabiri, A

2012-01-01

Activity Based Costing (ABC) is one of the new methods began appearing as a costing methodology in the 1990's. It calculates cost price by determining the usage of resources. In this study, ABC method was used for calculating cost price of remedial services in hospitals. To apply ABC method, Shahid Faghihi Hospital was selected. First, hospital units were divided into three main departments: administrative, diagnostic, and hospitalized. Second, activity centers were defined by the activity analysis method. Third, costs of administrative activity centers were allocated into diagnostic and operational departments based on the cost driver. Finally, with regard to the usage of cost objectives from services of activity centers, the cost price of medical services was calculated. The cost price from ABC method significantly differs from tariff method. In addition, high amount of indirect costs in the hospital indicates that capacities of resources are not used properly. Cost price of remedial services with tariff method is not properly calculated when compared with ABC method. ABC calculates cost price by applying suitable mechanisms but tariff method is based on the fixed price. In addition, ABC represents useful information about the amount and combination of cost price services.

Dynamics of 'abc' and 'qd' constant parameters induction generator model

DEFF Research Database (Denmark)

Fajardo-R, L.A.; Medina, A.; Iov, F.

2009-01-01

In this paper, parametric sensibility effects on dynamics of the induction generator in the presence of local perturbations are investigated. The study is conducted in a 3x2 MW wind park dealing with abc, qd0 and qd reduced order, induction generator model respectively, and with fluxes as state...

Is the ABC pain scale reliable for premature babies?

Science.gov (United States)

Bellieni, Cv; Maffei, M; Ancora, G; Cordelli, D; Mastrocola, M; Faldella, G; Ferretti, E; Buonocore, G

2007-07-01

We recently developed the ABC scale to assess pain in term newborns. The aim of the present study was to assess the reliability of the scale in preterm babies. The scale consists of three cry parameters: (a) pitch of the first cry, (b) rhythmicity of the bout of crying and (c) cry constancy. Changes in these parameters were previously found to distinguish medium and high levels of pain as evaluated by spectral analysis of crying. We enrolled 72 babies to perform the steps usually requested to validate a scale, namely the study of the concurrent validity, specificity and sensibility. Moreover, we assessed the interjudge reliability and the clinical utility and ease of the scale. A good correlation (r = 0.68; r(2)= 0.45; p babies who underwent pain and babies who underwent non-painful stimulus.) Interobserver reliability was good: Cohen's kappa = 0.7. The good correlation between the two scales shows that the ABC scale is also reliable for premature babies.

The 22nd Annual Precise Time and Time Interval (PTTI) Applications and Planning Meeting

International Nuclear Information System (INIS)

Sydnor, R.L.

1990-05-01

Papers presented at the 22nd Annual Precise Time and Time Interval (PTTI) Applications and Planning Meeting are compiled. The following subject areas are covered: Rb, Cs, and H-based frequency standards and cryogenic and trapped-ion technology; satellite laser tracking networks, GLONASS timing, intercomparison of national time scales and international telecommunications; telecommunications, power distribution, platform positioning, and geophysical survey industries; military communications and navigation systems; and dissemination of precise time and frequency by means of GPS, GLONASS, MIL STAR, LORAN, and synchronous communication satellites

Insight into Two ABC Transporter Families Involved in Lantibiotic Resistance

Directory of Open Access Journals (Sweden)

Rebecca Clemens

2018-01-01

Full Text Available Antimicrobial peptides, which contain (methyl-lanthionine-rings are called lantibiotics. They are produced by several Gram-positive bacteria and are mainly active against these bacteria. Although these are highly potent antimicrobials, some human pathogenic bacteria express specific ABC transporters that confer resistance and counteract their antimicrobial activity. Two distinct ABC transporter families are known to be involved in this process. These are the Cpr- and Bce-type ABC transporter families, named after their involvement in cationic peptide resistance in Clostridium difficile, and bacitracin efflux in Bacillus subtilis, respectively. Both resistance systems differentiate to each other in terms of the proteins involved. Here, we summarize the current knowledge and describe the divergence as well as the common features present in both the systems to confer lantibiotic resistance.

Differential contributions of five ABC transporters to mutidrug resistance, antioxidion and virulence of Beauveria bassiana, an entomopathogenic fungus.

Directory of Open Access Journals (Sweden)

Ting-Ting Song

Full Text Available Multidrug resistance (MDR confers agrochemical compatibility to fungal cells-based mycoinsecticdes but mechanisms involved in MDR remain poorly understood for entomopathogenic fungi, which have been widely applied as biocontrol agents against arthropod pests. Here we characterized the functions of five ATP-binding cassette (ABC transporters, which were classified to the subfamilies ABC-B (Mdr1, ABC-C (Mrp1 and ABC-G (Pdr1, Pdr2 and Pdr5 and selected from 54 full-size ABC proteins of Beauveria bassiana based on their main domain architecture, membrane topology and transcriptional responses to three antifungal inducers. Disruption of each transporter gene resulted in significant reduction in resistance to four to six of eight fungicides or antifungal drugs tested due to their differences in structure and function. Compared with wild-type and complemented (control strains, disruption mutants of all the five transporter genes became significantly less tolerant to the oxidants menadione and H₂O₂ based on 22-41% and 10-31% reductions of their effective concentrations required for the suppression of 50% colony growth at 25°C. Under a standardized spray, the killing actions of ΔPdr5 and ΔMrp1 mutants against Spodoptera litura second-instar larvae were delayed by 59% and 33% respectively. However, no significant virulence change was observed in three other delta mutants. Taken together, the examined five ABC transporters contribute differentially to not only the fungal MDR but antioxidant capability, a phenotype rarely associated with ABC efflux pumps in previous reports; at least some of them are required for the full virulence of B. bassiana, thereby affecting the fungal biocontrol potential. Our results indicate that ABC pump-dependent MDR mechanisms exist in entomopathogenic fungi as do in yeasts and human and plant pathogenic fungi.

Preliminary lifetime predictions for 304 stainless steel as the LANL ABC blanket material

International Nuclear Information System (INIS)

Park, J.J.; Buksa, J.J.; Houts, M.G.; Arthur, E.D.

1997-11-01

The prediction of materials lifetime in the preconceptual Los Alamos National Laboratory (LANL) Accelerator-Based Conversion of Plutonium (ABC) is of utmost interest. Because Hastelloy N showed good corrosion resistance to the Oak Ridge National Laboratory Molten Salt Reactor Experiment fuel salt that is similar to the LANL ABC fuel salt, Hastelloy N was originally proposed for the LANL ABC blanket material. In this paper, the possibility of using 304 stainless steel as a replacement for the Hastelloy N is investigated in terms of corrosion issues and fluence-limit considerations. An attempt is made, based on the previous Fast Flux Test Facility design data, to predict the preliminary lifetime estimate of the 304 stainless steel used in the blanket region of the LANL ABC

ABC transporters and xenobiotic defense systems in early life stages of rainbow trout (Oncorhynchus mykiss).

Science.gov (United States)

Kropf, Christian; Segner, Helmut; Fent, Karl

2016-01-01

Embryos of oviparous fish, in contrast to (ovo) viviparous species, develop in the aquatic environment, and therefore need solute transport systems at their body surfaces for maintaining internal homeostasis and defending against potentially harmful substances. We hypothesized that solute transporters undergo changes in tissue distribution from the embryo to the larval stage. We therefore studied the mRNA profiles of eight ABC transporters (abcb1a, abcb1b, abcc1, abcc2, abcc3, abcc4, abcc5, abcg2) and three solute carriers (oatp1d, putative oatp2 putative, mate1) in different body regions (head, yolk sac epithelium, abdominal viscera, skin/muscles) of developing rainbow trout. Additionally, we investigated mRNA levels of phase I (cyp1a, cyp3a) and phase II (gstp, putative ugt1, putative ugt2) biotransformation enzymes. The study covered the developmental period from the eleuthero-embryo stage to the first-feeding larval stage (1-20days post-hatch, dph). At 1dph, transcripts of abcc2, abcc4, abcg2, cyp3a, gstp, putative mate1, and putative oatp2 occurred primarily in the yolk sac epithelium, whereas at later stages expression of these genes was predominantly observed in the abdominal viscera. The functional activity of ABC transporters in fish early life stages was assessed by rhodamine B accumulation assays. Finally, we investigated the potential impact of xenobiotics (clotrimazole, clofibric acid) on the ABC and biotransformation systems of trout early life stages. While clofibric acid had no effect, clotrimazole lead to an increased rhodamine B accumulation. The results provide evidence that the transition from the eleuthero-embryo to the larval stage is accompanied by a major alteration in tissue expression of ABC transporters. Copyright © 2016 Elsevier Inc. All rights reserved.

Single liposome analysis of peptide translocation by the ABC transporter TAPL.

Science.gov (United States)

Zollmann, Tina; Moiset, Gemma; Tumulka, Franz; Tampé, Robert; Poolman, Bert; Abele, Rupert

2015-02-17

ATP-binding cassette (ABC) transporters use ATP to drive solute transport across biological membranes. Members of this superfamily have crucial roles in cell physiology, and some of the transporters are linked to severe diseases. However, understanding of the transport mechanism, especially of human ABC exporters, is scarce. We reconstituted the human lysosomal polypeptide ABC transporter TAPL, expressed in Pichia pastoris, into lipid vesicles (liposomes) and performed explicit transport measurements. We analyzed solute transport at the single liposome level by monitoring the coincident fluorescence of solutes and proteoliposomes in the focal volume of a confocal microscope. We determined a turnover number of eight peptides per minute, which is two orders of magnitude higher than previously estimated from macroscopic measurements. Moreover, we show that TAPL translocates peptides against a large concentration gradient. Maximal filling is not limited by an electrochemical gradient but by trans-inhibition. Countertransport and reversibility studies demonstrate that peptide translocation is a strictly unidirectional process. Altogether, these data are included in a refined model of solute transport by ABC exporters.

APLICATION OF ABC METHOD FROM AN OPERATOR OF WATER AND SEWERAGE

Directory of Open Access Journals (Sweden)

FÜLÖP ÁRPÁD-ZOLTÁN

2016-12-01

Full Text Available At the time of the appearance of the ABC method, many specialists considered that they found the most opportune method of calculation to allocate the overhead costs on the cost objects, otherwise said to be able to calculate the total cost of a product or service. Because the method is based on determining the total cost, we can consider that the ABC method is not a method of costing, but rather a method of cost management. Unfortunately, in the specialized literature of Roumania there are many approaches which consider that the ABC method is a method of costing in the traditional way, although in our opinion it is not. Application of ABC method to a regional operator of water and sewerage shows us the possibilities of the method, the possibilities that are offered in the field of cost and administration overhead management, respectively of the establishment of the accounting result on the different cost objects. In case of the regional operator the calculation object is the city or township in which provides the services of water and sewage.

SU-E-T-326: The Oxygen Saturation (SO2) and Breath-Holding Time Variation Applied Active Breathing Control (ABC)

Energy Technology Data Exchange (ETDEWEB)

Gong, G; Yin, Y [Shandong Cancer Hospital, Jinan, Shandong (China)

2014-06-01

Purpose: To study the oxygen saturation (SO2) and breath-holding time variation applied active breathing control (ABC) in radiotherapy of tumor. Methods: 24 volunteers were involved in our trials, and they all did breath-holding motion assisted by ELEKTA Active Breathing Coordinator 2.0 for 10 times respectively. And the patient monitor was used to observe the oxygen saturation (SO2) variation. The variation of SO2, and length of breath-holding time and the time for recovering to the initial value of SO2 were recorded and analyzed. Results: (1) The volunteers were divided into two groups according to the SO2 variation in breath-holding: A group, 14 cases whose SO2 reduction were more than 2% (initial value was 97% to 99%, while termination value was 91% to 96%); B group, 10 cases were less than 2% in breath-holding without inhaling oxygen. (2) The interfraction breath holding time varied from 8 to 20s for A group compared to the first breath-holding time, and for B group varied from 4 to 14s. (3) The breathing holding time of B group prolonged mean 8s, compared to A group. (4) The time for restoring to the initial value of SO2 was from 10s to 30s. And the breath-holding time shortened obviously for patients whose SO2 did not recover to normal. Conclusion: It is very obvious that the SO2 reduction in breath-holding associated with ABC for partial people. It is necessary to check the SO2 variation in breath training, and enough time should be given to recover SO2.

Structure of the nucleotide-binding domain of a dipeptide ABC transporter reveals a novel iron-sulfur cluster-binding domain.

Science.gov (United States)

Li, Xiaolu; Zhuo, Wei; Yu, Jie; Ge, Jingpeng; Gu, Jinke; Feng, Yue; Yang, Maojun; Wang, Linfang; Wang, Na

2013-02-01

Dipeptide permease (Dpp), which belongs to an ABC transport system, imports peptides consisting of two or three L-amino acids from the matrix to the cytoplasm in microbes. Previous studies have indicated that haem competes with dipeptides to bind DppA in vitro and in vivo and that the Dpp system can also translocate haem. Here, the crystal structure of DppD, the nucleotide-binding domain (NBD) of the ABC-type dipeptide/oligopeptide/nickel-transport system from Thermoanaerobacter tengcongensis, bound with ATP, Mg(2+) and a [4Fe-4S] iron-sulfur cluster is reported. The N-terminal domain of DppD shares a similar structural fold with the NBDs of other ABC transporters. Interestingly, the C-terminal domain of DppD contains a [4Fe-4S] cluster. The UV-visible absorbance spectrum of DppD was consistent with the presence of a [4Fe-4S] cluster. A search with DALI revealed that the [4Fe-4S] cluster-binding domain is a novel structural fold. Structural analysis and comparisons with other ABC transporters revealed that this iron-sulfur cluster may act as a mediator in substrate (dipeptide or haem) binding by electron transfer and may regulate the transport process in Dpp ABC transport systems. The crystal structure provides a basis for understanding the properties of ABC transporters and will be helpful in investigating the functions of NBDs in the regulation of ABC transporter activity.

78 FR 61828 - Fisheries of the Northeastern United States; Atlantic Herring Fishery; Framework Adjustment 2 and...

Science.gov (United States)

2013-10-04

...: Carrie Nordeen, Fishery Policy Analyst, (978) 281-9272, fax (978) 281-9135. SUPPLEMENTARY INFORMATION... the overfishing limit (OFL), acceptable biological catch (ABC), annual catch limit (ACL), optimum... area. This measure maintains the management uncertainty buffer between ABC and the stock-wide ACL...

ABC estimation of unit costs for emergency department services.

Science.gov (United States)

Holmes, R L; Schroeder, R E

1996-04-01

Rapid evolution of the health care industry forces managers to make cost-effective decisions. Typical hospital cost accounting systems do not provide emergency department managers with the information needed, but emergency department settings are so complex and dynamic as to make the more accurate activity-based costing (ABC) system prohibitively expensive. Through judicious use of the available traditional cost accounting information and simple computer spreadsheets. managers may approximate the decision-guiding information that would result from the much more costly and time-consuming implementation of ABC.

Biodiversity Monitoring Using NGS Approaches on Unusual Substrates (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

Energy Technology Data Exchange (ETDEWEB)

Gilbert, Tom

2013-03-01

Tom Gilbert of the Natural History Museum of Denmark on "Biodiversity monitoring using NGS approaches on unusual substrates" at the 8th Annual Genomics of Energy & Environment Meeting in Walnut Creek, Calif.

Proceedings of the 5th annual meeting of Japanese Society of Radiation Safety Management 2006 Nagoya

International Nuclear Information System (INIS)

2006-01-01

This is the program and the proceedings of the 5th annual meeting of Japanese Society of Radiation Safety Management held from November 29th through December 1st of 2006. The sessions held are: (1) Radiation Measurement 1, (2) Education Method, (3) Radiation Control, (4) Waste Handling, Contamination Inspection, and Renewal, (5) Exposure Reduction, Radiation Evaluation, and Radioactivity Control (6) Radiation Measurement 2, (7) Operation Environment, (8) Medical Exposure, (9) Radiation Measurement 3, (10) Software, IT Technology, and Data Processing, (11) Emission and Drainage Handling, and (12) Radiation Effect and Contamination Countermeasure. The poster sessions held are: (1) Radiation Measurement, (2) Environmental Radiation, (3) Scattering Rate, Penetration Rate, and Contamination Inspection, (4) Education Method, (5) Medical Exposure, (6) Access Control and Software, and (7) Radiation Control Method and Monitoring. The symposia held are: (1) 'Toward Establishment of Guideline for Safe X-ray Handling Education' and 'International Situation of Radiation Safety'. 2 keynote lectures were also held. (S.K.)

Metodologia ABC: implantação numa microempresa ABC methodology: implementation on a micro firm

Directory of Open Access Journals (Sweden)

Orlando Duran

2000-08-01

Full Text Available Este trabalho relata a implantação da metodologia de custos baseados em atividades numa microempresa do ramo metalúrgico. A proposta pretende demonstrar a viabilidade de aplicar esta técnica em empresas sem importar seu tamanho, só realizando algumas adaptações que garantam baixo investimento e curto espaço de tempo para obter os resultados. Na parte final do trabalho se realiza uma análise dos resultados obtidos verificando-se o potencial da informação gerada pela metodologia e seu uso como ferramenta de gestão.This paper presents an implementation of the activity based costing (ABC methodology in a small firm. The approach presented is intended to demonstrate the feasibility of applying the ABC methodology at any sized firm, only through few adaptations for ensuring low investments fees and speed in obtaining results and information from the system. Discussion about the results obtained during the implementation case are presented and the potential of using the information generated from the system as a managing tool is commented.

Meeting Mid-Year Meeting

Indian Academy of Sciences (India)

23 Newsletter of the Indian Academy of ScienCE. 57th Annual. Meeting ... Srinivas, Institute for Social and Economic. Change ... "Quantum mechanics and statistical mechanics of anyons" .... Special Issue on Geomagnetic Methods and.

XVIIIth annual meeting of the Spanish Nuclear Society, Puerto de Santa Maria 28,29,30 October 1992 Program and abstracts

International Nuclear Information System (INIS)

1992-01-01

The presentation and the abstracts of each session in XVIIIth. Annual meeting of the Spanish Nuclear Society are contained. The principal sessions are: - Environmental aspects of Nuclear Energy - R+D in Nuclear Fusion - Materials - Radiation protection - Severe Accidents

The ABCs of Activity-Based Costing: A Cost Containment and Reallocation Tool.

Science.gov (United States)

Turk, Frederick J.

1992-01-01

This article describes activity-based costing (ABC) and how this tool may help management understand the costs of major activities and identify possible alternatives. Also discussed are the traditional costing systems used by higher education and ways of applying ABC to higher education. (GLR)

Appendix A.3. Minutes from meeting of the 1995th Joint Annual Report's Proposals and on the Slovak-Hungarian monitoring of underwater weir impacts according to the Inter-governmental Agreement held on October 10, 1996 in Gyoer

International Nuclear Information System (INIS)

1997-01-01

This part contains: (1) Points of the agenda: 1. Evaluation of the water discharged by the Slovak Party according to the Agreement from 1995; 2. Information about the monitoring data exchange: - surface and groundwater regimes in 1996, - surface and ground water quality, - soil moisture, - bio-monitoring including Proposals in the 1995 th Joint Annual Report; 3 Schedule of the 1995 th Joint Annual Report's proposals fulfillment; 4 Tasks concerning the 1996 th National and Annual Reports preparation. In the annexes tabular forms and digital formats for data exchange are presented: Surface water discharge; Surface water level; Surface water quality, Ground Water level; Ground Water quality; Soil moisture. (2) Annex 1: Minutes from meeting of experts for surface and ground water regime and quality held on September 11, 1996 in Bratislava. (3) Annex 2: Minutes from meeting of experts for soil moisture monitoring and biology held on October 2, 1996 in Mosonmagyarovar

Proceedings of the 17. Annual Meeting of the Brazilian Chemistry Society; 7. National Symposium on Inorganic Chemistry. Abstracts

International Nuclear Information System (INIS)

1994-01-01

These 17. Annual Meeting of the Brazilian Chemistry Society and 7. National Symposium on Inorganic Chemistry present several subjects of different interests for the participants, including sections about inorganic chemistry; organic chemistry; environmental chemistry; technological chemistry; electrochemistry; physical chemistry; photochemistry; chemical education; natural products; analytical chemistry and biological chemistry. (C.G.C.)

Phylogenetic analysis of fungal ABC transporters

NARCIS (Netherlands)

Kovalchuk, A.; Driessen, A.J.M.

2010-01-01

Background: The superfamily of ABC proteins is among the largest known in nature. Its members are mainly, but not exclusively, involved in the transport of a broad range of substrates across biological membranes. Many contribute to multidrug resistance in microbial pathogens and cancer cells. The

75 FR 49549 - ABC & D Recycling, Inc.-Lease and Operation Exemption-a Line of Railroad in Ware, MA

Science.gov (United States)

2010-08-13

... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35397] ABC & D Recycling, Inc.--Lease and Operation Exemption--a Line of Railroad in Ware, MA ABC & D Recycling, Inc. (ABC & D..., ABC & D Recycling, Inc.--Lease and Operation Exemption--a Line of Railroad in Ware, Massachusetts (STB...

Progress report on nuclear science and technology in China (Vol.3). Proceedings of academic annual meeting of China Nuclear Society in 2013, No.2--uranium mining and metallurgy sub-volume

International Nuclear Information System (INIS)

2014-05-01

Progress report on nuclear science and technology in China (Vol. 3) includes 48 articles which are communicated on the third national academic annual meeting of China Nuclear Society. There are 10 books totally. This is the second one, the content is about uranium mining and metallurgy sub-volume

Progress report on nuclear science and technology in China (Vol.1). Proceedings of academic annual meeting of China Nuclear Society in 2009, No.2--nuclear power sub-volume (Pt.1)

International Nuclear Information System (INIS)

2010-11-01

Progress report on nuclear science and technology in China (Vol. 1) includes 889 articles which are communicated on the first national academic annual meeting of China Nuclear Society. There are 10 books totally. This is the second one, the content is about uranium mining, uranium metallurgy and nuclear power.

Progress report on nuclear science and technology in China (Vol.1). Proceedings of academic annual meeting of China Nuclear Society in 2009, No.2--uranium mining and metallurgy sub-volume

International Nuclear Information System (INIS)

2010-11-01

Progress report on nuclear science and technology in China (Vol. 1) includes 889 articles which are communicated on the first national academic annual meeting of China Nuclear Society. There are 10 books totally. This is the second one, the content is about uranium mining, uranium metallurgy and nuclear power.

Strategic analysis of ABC Systems and its potential future product

OpenAIRE

Lam, Nancy M.

2006-01-01

ABC Systems Limited is a provider of data communication software. Its main product line is protocol conversion software. ABC has developed several other products including some hardware products, but the main success remains the protocol conversion software developed over 10 years ago. The company is having difficulties discovering and developing a profitable and achievable new product and target market. The need for the protocol conversion software is diminishing as the standard of TCP/IP is...

78 FR 46897 - Fisheries of the Northeastern United States; Atlantic Herring Fishery; Framework Adjustment 2 and...

Science.gov (United States)

2013-08-02

... CONTACT: Carrie Nordeen, Fishery Policy Analyst, (978) 281-9272, fax (978) 281-9135. SUPPLEMENTARY... overfishing limit (OFL), acceptable biological catch (ABC), annual catch limit (ACL), optimum yield (OY... uncertainty buffer between ABC and the stock-wide ACL, while giving the fleet some flexibility in choosing...

American Vocational Education Research Association (AVERA) Annual Research Meeting in Conjunction with the Annual Convention of the Association for Career and Technical Education. Proceedings (Orlando, Florida, December 11-13, 1999).

Science.gov (United States)

Camp, William G., Ed.

This document contains 14 research papers presented at the American Vocational Education Research Association (AVERA) annual meeting. The following papers are included: "Factors that Influence Students to Attend 4-Year Automotive Programs" (Gregory G. Belcher, Robert L. Frisbee); "The Training Needs of Vocational Teachers for…

Genome-Wide Identification, Characterization and Phylogenetic Analysis of ATP-Binding Cassette (ABC) Transporter Genes in Common Carp (Cyprinus carpio).

Science.gov (United States)

Liu, Xiang; Li, Shangqi; Peng, Wenzhu; Feng, Shuaisheng; Feng, Jianxin; Mahboob, Shahid; Al-Ghanim, Khalid A; Xu, Peng

2016-01-01

The ATP-binding cassette (ABC) gene family is considered to be one of the largest gene families in all forms of prokaryotic and eukaryotic life. Although the ABC transporter genes have been annotated in some species, detailed information about the ABC superfamily and the evolutionary characterization of ABC genes in common carp (Cyprinus carpio) are still unclear. In this research, we identified 61 ABC transporter genes in the common carp genome. Phylogenetic analysis revealed that they could be classified into seven subfamilies, namely 11 ABCAs, six ABCBs, 19 ABCCs, eight ABCDs, two ABCEs, four ABCFs, and 11 ABCGs. Comparative analysis of the ABC genes in seven vertebrate species including common carp, showed that at least 10 common carp genes were retained from the third round of whole genome duplication, while 12 duplicated ABC genes may have come from the fourth round of whole genome duplication. Gene losses were also observed for 14 ABC genes. Expression profiles of the 61 ABC genes in six common carp tissues (brain, heart, spleen, kidney, intestine, and gill) revealed extensive functional divergence among the ABC genes. Different copies of some genes had tissue-specific expression patterns, which may indicate some gene function specialization. This study provides essential genomic resources for future studies in common carp.

Genome-Wide Identification, Characterization and Phylogenetic Analysis of ATP-Binding Cassette (ABC) Transporter Genes in Common Carp (Cyprinus carpio)

Science.gov (United States)

Peng, Wenzhu; Feng, Shuaisheng; Feng, Jianxin; Mahboob, Shahid; Al-Ghanim, Khalid A.

2016-01-01

The ATP-binding cassette (ABC) gene family is considered to be one of the largest gene families in all forms of prokaryotic and eukaryotic life. Although the ABC transporter genes have been annotated in some species, detailed information about the ABC superfamily and the evolutionary characterization of ABC genes in common carp (Cyprinus carpio) are still unclear. In this research, we identified 61 ABC transporter genes in the common carp genome. Phylogenetic analysis revealed that they could be classified into seven subfamilies, namely 11 ABCAs, six ABCBs, 19 ABCCs, eight ABCDs, two ABCEs, four ABCFs, and 11 ABCGs. Comparative analysis of the ABC genes in seven vertebrate species including common carp, showed that at least 10 common carp genes were retained from the third round of whole genome duplication, while 12 duplicated ABC genes may have come from the fourth round of whole genome duplication. Gene losses were also observed for 14 ABC genes. Expression profiles of the 61 ABC genes in six common carp tissues (brain, heart, spleen, kidney, intestine, and gill) revealed extensive functional divergence among the ABC genes. Different copies of some genes had tissue-specific expression patterns, which may indicate some gene function specialization. This study provides essential genomic resources for future studies in common carp. PMID:27058731

Genome-Wide Identification, Characterization and Phylogenetic Analysis of ATP-Binding Cassette (ABC Transporter Genes in Common Carp (Cyprinus carpio.

Directory of Open Access Journals (Sweden)

Xiang Liu

Full Text Available The ATP-binding cassette (ABC gene family is considered to be one of the largest gene families in all forms of prokaryotic and eukaryotic life. Although the ABC transporter genes have been annotated in some species, detailed information about the ABC superfamily and the evolutionary characterization of ABC genes in common carp (Cyprinus carpio are still unclear. In this research, we identified 61 ABC transporter genes in the common carp genome. Phylogenetic analysis revealed that they could be classified into seven subfamilies, namely 11 ABCAs, six ABCBs, 19 ABCCs, eight ABCDs, two ABCEs, four ABCFs, and 11 ABCGs. Comparative analysis of the ABC genes in seven vertebrate species including common carp, showed that at least 10 common carp genes were retained from the third round of whole genome duplication, while 12 duplicated ABC genes may have come from the fourth round of whole genome duplication. Gene losses were also observed for 14 ABC genes. Expression profiles of the 61 ABC genes in six common carp tissues (brain, heart, spleen, kidney, intestine, and gill revealed extensive functional divergence among the ABC genes. Different copies of some genes had tissue-specific expression patterns, which may indicate some gene function specialization. This study provides essential genomic resources for future studies in common carp.

mRMR-ABC: A Hybrid Gene Selection Algorithm for Cancer Classification Using Microarray Gene Expression Profiling

Directory of Open Access Journals (Sweden)

Hala Alshamlan

2015-01-01

Full Text Available An artificial bee colony (ABC is a relatively recent swarm intelligence optimization approach. In this paper, we propose the first attempt at applying ABC algorithm in analyzing a microarray gene expression profile. In addition, we propose an innovative feature selection algorithm, minimum redundancy maximum relevance (mRMR, and combine it with an ABC algorithm, mRMR-ABC, to select informative genes from microarray profile. The new approach is based on a support vector machine (SVM algorithm to measure the classification accuracy for selected genes. We evaluate the performance of the proposed mRMR-ABC algorithm by conducting extensive experiments on six binary and multiclass gene expression microarray datasets. Furthermore, we compare our proposed mRMR-ABC algorithm with previously known techniques. We reimplemented two of these techniques for the sake of a fair comparison using the same parameters. These two techniques are mRMR when combined with a genetic algorithm (mRMR-GA and mRMR when combined with a particle swarm optimization algorithm (mRMR-PSO. The experimental results prove that the proposed mRMR-ABC algorithm achieves accurate classification performance using small number of predictive genes when tested using both datasets and compared to previously suggested methods. This shows that mRMR-ABC is a promising approach for solving gene selection and cancer classification problems.

mRMR-ABC: A Hybrid Gene Selection Algorithm for Cancer Classification Using Microarray Gene Expression Profiling.

Science.gov (United States)

Alshamlan, Hala; Badr, Ghada; Alohali, Yousef

2015-01-01

An artificial bee colony (ABC) is a relatively recent swarm intelligence optimization approach. In this paper, we propose the first attempt at applying ABC algorithm in analyzing a microarray gene expression profile. In addition, we propose an innovative feature selection algorithm, minimum redundancy maximum relevance (mRMR), and combine it with an ABC algorithm, mRMR-ABC, to select informative genes from microarray profile. The new approach is based on a support vector machine (SVM) algorithm to measure the classification accuracy for selected genes. We evaluate the performance of the proposed mRMR-ABC algorithm by conducting extensive experiments on six binary and multiclass gene expression microarray datasets. Furthermore, we compare our proposed mRMR-ABC algorithm with previously known techniques. We reimplemented two of these techniques for the sake of a fair comparison using the same parameters. These two techniques are mRMR when combined with a genetic algorithm (mRMR-GA) and mRMR when combined with a particle swarm optimization algorithm (mRMR-PSO). The experimental results prove that the proposed mRMR-ABC algorithm achieves accurate classification performance using small number of predictive genes when tested using both datasets and compared to previously suggested methods. This shows that mRMR-ABC is a promising approach for solving gene selection and cancer classification problems.

Critérios para aplicação de ABC (Activity Based Costing na indústria naval Criteria for applying Activity Based Costing (ABC in the naval construction industry

Directory of Open Access Journals (Sweden)

Nélio Achão Filho

2003-01-01

Full Text Available O presente trabalho tem por objetivo conceituar o que é ABC (Activity Based Costing e apresentar, de forma sistemática, uma sugestão de critérios para aplicação em empresa de construção naval. Basicamente, o estudo pretende contribuir, através do efeito demonstração do estudo de caso, para a conscientização quanto as dificuldades e oportunidades oferecidas pela implementação de um sistema ABC, numa área carente de novas metodologias gerenciais.The objective of this article is to evaluate what ABC (Activity Based Costing is, and to present, in a systematic form, a suggestion for the implantation of criteria for aplication at a naval construction company. Basically, the study intends, through the case study demo, make executives aware of the dificulties and oportunities offered by the implementation of an ABC system, in an area in need of new managerial methods.

Standing Concertation Committee - Ordinary meeting on 2 March 2005

CERN Multimedia

2005-01-01

Original: English This meeting was devoted to the main topics summarised below. 1. MAPS - Preparation for the 2005 exercise The SCC agreed the text of the ‘2005 Guidelines for Advancement and Promotion', subject to some amendments. (See Official News Article below) As regards the numerical budgetary guidelines for this year's exercise, the Chairman announced that the Management agreed to grant 30 additional steps as a transitional measure, which had also been the case for the 2003 and 2004 exercises. 2. Annual carry-over of leave (Article R II 4.07 of the Staff Regulations) The SCC examined the Management's proposal to increase the possibility of carry-over of annual leave (currently 30 days) from one leave year to the next, up to the end of the 2007 / 2008 leave year. After some discussion, it was agreed to limit this supplementary carry-over of leave to 10 days* and to exceptional cases only, essentially concerning crucial LHC activities. Such cases would be subject to approval by the hierar...

2011 annual meeting of the Deutsche Gesellschaft fuer Zerstoerungsfreie Pruefung (DGZfP). NDE in research, development and application

International Nuclear Information System (INIS)

2011-01-01

This CD-ROM proceedings publication contains the papers and posters of the DGZfP annual meeting 2011, at Bremen, Germany, both in full text and as PowerPoint presentations. The following issues were discussed: Radiographic inspection, ultrasonic inspection, computerized tomography, and thermography. Ten papers were recorded as separate entries in the ENERGY database. [de

2013 annual meeting of the Deutsche Gesellschaft fuer Zerstoerungsfreie Pruefung (DGZfP). NDE in research, development and application

International Nuclear Information System (INIS)

2013-01-01

This CD-ROM proceedings publication contains the papers and posters of the DGZfP annual meeting 2013, at Bremen, Germany, both in full text and as PowerPoint presentations. The following issues were discussed: computerized tomography, thermography; radiographic, ultrasonic, eddy current and microwave testing. 13 papers were recorded as separate entries in the INIS database.

ABCs of Oral Health: Nutrition - Children

Science.gov (United States)

... for gum inflammation and cavities. More ABCs of Oral Health A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | All Nutrition - Adults Nutrition - Children Home | InfoBites | Find a Dentist | ...

European Pharmaceutical Pricing and Reimbursement--SMi's 21st Annual Meeting (October 5-6, 2015--London, UK).

Science.gov (United States)

Kibble, A; D'Souza, P

2015-10-01

Translating perceived market value for pharmaceutical products into a willingness to pay remains the key factor in ensuring market access and return on investment. How price is managed in the context of new market entrants or new approval settings can create complex challenges, and further complexity is added through diverse global reimbursement structures and the myriad of stakeholders involved at every step of value identification. SMi's 21st Annual Meeting on European Pricing and Reimbursement presented a program focused on the measures being taken by European healthcare systems as they seek to facilitate access to the latest treatments while delivering value for payers and patients. Supporting patient access to life-changing medicines is a challenge, and funders are responding in many different ways; however, while the pharma industry continues to focus its efforts on high cost drugs that treat diseases of the few, the disconnect will be not be resolved. The speakers and delegates at the annual meeting believe success is possible by focusing on value for patients, driven by provider experience, scale and learning. Instead of simply lowering costs, companies, providers and payers can more adequately contribute to the goals of funders as well as the treatment needs of patients. Copyright 2015 Prous Science, S.A.U. or its licensors. All rights reserved.

Conversion rates of abstracts presented at the Urological Society of Australia and New Zealand (USANZ) Annual Scientific Meeting into full-text journal articles.

Science.gov (United States)

Yoon, Peter D; Chalasani, Venu; Woo, Henry H

2012-08-01

What's known on the subject? and What does the study add? It is well known that the transition of a presented abstract in a scientific meeting to a journal article improves the quality of the meeting and prevents an abstract being incorporated into meta-analyses or practice guidelines without proper appraisal. This is the first analysis of USANZ Annual Scientific Meeting abstracts' conversion to full publication. With relatively low publication rates compared to other international meetings, this review identifies the need for mechanisms to encourage USANZ researchers to convert their abstracts into published articles. The numbers and characteristics of the abstracts presented at the Annual Scientific Meetings (ASM) of the Urological Society of Australia and New Zealand (USANZ) that are converted to peer-reviewed publications have not previously been analysed and published. We undertook a review of all abstracts presented at the USANZ ASM from 2005 to 2009. A PubMed search was performed between 15 June and 15 July 2012, using a search algorithm to identify the full-text publications of the presented abstracts. Correlation between abstract characteristics and publication rate was then examined to distinguish the predictors for publications. Of 614 abstracts that were presented at USANZ ASM between 2005 and 2009, 183 papers were published, giving a publication rate of 29.80%. The papers were predominantly published in urological journals and were more likely to be published if they were presented by an international author or were retrospective studies or if basic science research. The mean (SD) time to publication was 14.46 (13.89) months and the mean Impact Factor of journals where papers were published was 2.90. The overall publication rate was relatively low compared with other urological meetings held in America and Europe. USANZ has a challenge of encouraging higher-quality research from the authors to further enhance its publication rate and consequently the

Trends in safety pharmacology: posters presented at the annual meetings of the Safety Pharmacology Society 2001-2010.

Science.gov (United States)

Redfern, William S; Valentin, Jean-Pierre

2011-01-01

The inaugural meeting of the Safety Pharmacology Society (SPS) was in 2001, soon after ICH S7A had been adopted. The 10th anniversary is an appropriate milestone at which to analyse trends in the science and themes of safety pharmacology, as reflected in posters presented at the annual meetings. The source information was the poster abstract booklets from each of the first ten annual meetings. The number of posters rose steadily from 34 in 2001 to 201 in 2010. The proportion of posters containing in vitro data has remained constant throughout the decade at ~30%. In terms of organ functions, themes relating to the cardiovascular system (CVS) have always generated the majority of posters, remaining above 60% of the total for the last 9years. The dominant theme has been around 'QT liability'. This peaked in 2003 at 68% of all posters presented, around the time of the ICHS7B discussions, and has remained above 30% thereafter. Apart from 2003 (dipping to 4%), CNS-related posters have remained steady at 11-17% throughout the decade. Respiratory-related posters have remained at 5-8% over the last 5years. Gastrointestinal (GI)-related posters have contributed 2-6% throughout the decade, and renal-related posters 1-3%. Posters on combined organ assessments have appeared in recent years. The relative emphasis on the different organ functions is broadly proportional to the causes of candidate drug attrition preclinically, whereas both CNS and GI are under-represented when considering their contribution to significant adverse effects during clinical development. Trends are either regulatory-driven (e.g. increase in posters on abuse-dependence liability since EMEA/CHMP/SWP/94227/2004), technology-driven (e.g. automated hERG assay; left ventricular function; non-invasive CVS measurements; stem cells, etc.), or relate to the predictive ability of safety pharmacology data (e.g. clinical translation initiatives; concordance between in vitro and in vivo preclinical data; integrated

Effects of the use of ABC weapons

International Nuclear Information System (INIS)

Karl-Rueckert, E.

1980-01-01

The effects of ABC-weapons are presented. The various classes of chemical weapons and their effects are discussed. It is pointed out that there is hardly a means of protection against these weapons. (MG) [de

Total Ionizing Dose Testing of the ABC130 ASIC for the ATLAS Phase-II Semiconductor Tracker Upgrade

CERN Document Server

Morningstar, Alan

2015-01-01

The Large Hadron Collider's (LHC) current inner detector was not built to withstand the radiation damage from the 3000 $\\text{fb}^{-1}$ of integrated luminosity that is planned for the high luminosity LHC (HL-LHC). Therefore, the ATLAS inner detector (ID) must be completely upgraded. As a part of this upgrade, the semiconductor tracker (SCT) and transition radiation tracker (TRT) will be replaced with new silicon microstrip sensors {[}1{]}. These silicon strips will be read out by the ABC130 chip and thus the ABC130 must be able to withstand an expected 30 Mrad of radiation over 10 years. The ABC130 chip was irradiated with 70 Mrad of x-ray radiation over the course of 2 days and the results are discussed in this report.

Joint Annual Meeting of the Austrian Physical Society and the Swiss Physical Society : with the Austrian ans Swiss Societies for Astronomy ans Astrophysics

CERN Document Server

2015-01-01

For the fourth time the annual meetings of ÖPG, SPS, SSAA and ÖGAA will take place together. The success of previous events in Innsbruck (2009), Lausanne (2011) and Linz (2013) indicates clearly that physicists from both countries appreciated the broader range of topics as well as the opportunity to meet colleagues from the other societies.

Association for Research in Vision and Ophthalmology (ARVO)--2010 Annual Meeting. For Sight: The Future of Eye and Vision Research--part 2.

Science.gov (United States)

Hookes, Livia

2010-07-01

The 2010 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), held in Fort Lauderdale, FL, USA, included topics covering new therapeutic developments in the field of eye and vision research. This conference report highlights selected presentations on the development of OT-440 (Othera Pharmaceuticals Inc) for the potential treatment of glaucoma, an extended-release implant of brimonidine (pSivida Corp) for ocular hypertension, AR-12286 (Aerie Pharmaceuticals Inc) for ocular hypertension or glaucoma, AC-8 (Calmune Corp/RiboVax Biotechnologies SA) for ocular diseases following HSV infection, and fidarestat (Sanwa Kagaku Kenkyusho Co Ltd) and the recombinant proteins NOV and NOVCter (INSERM/University Rene Descartes) for corneal neovascularization.

An Efficient ABC_DE_Based Hybrid Algorithm for Protein–Ligand Docking

Directory of Open Access Journals (Sweden)

Boxin Guan

2018-04-01

Full Text Available Protein–ligand docking is a process of searching for the optimal binding conformation between the receptor and the ligand. Automated docking plays an important role in drug design, and an efficient search algorithm is needed to tackle the docking problem. To tackle the protein–ligand docking problem more efficiently, An ABC_DE_based hybrid algorithm (ADHDOCK, integrating artificial bee colony (ABC algorithm and differential evolution (DE algorithm, is proposed in the article. ADHDOCK applies an adaptive population partition (APP mechanism to reasonably allocate the computational resources of the population in each iteration process, which helps the novel method make better use of the advantages of ABC and DE. The experiment tested fifty protein–ligand docking problems to compare the performance of ADHDOCK, ABC, DE, Lamarckian genetic algorithm (LGA, running history information guided genetic algorithm (HIGA, and swarm optimization for highly flexible protein–ligand docking (SODOCK. The results clearly exhibit the capability of ADHDOCK toward finding the lowest energy and the smallest root-mean-square deviation (RMSD on most of the protein–ligand docking problems with respect to the other five algorithms.