Custeio ABC no ambiente hospitalar: um estudo nos hospitais universitários e de ensino brasileiros ABC costing in hospital environment: a study in brazilian university hospitals

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Gilberto José Miranda

2007-08-01

Full Text Available O Custeio Baseado em Atividades tem se mostrado como uma alternativa promissora para fazer frente à complexidade que caracteriza os custos hospitalares. Nos últimos dez anos, somente na Plataforma Lattes, foram encontrados mais de uma centena de estudos dessa natureza. Este trabalho tem como objetivo, conhecer, empiricamente, a utilização do Custeio ABC nos hospitais universitários e de ensino brasileiros e comparar os resultados, conforme as possibilidades, com as pesquisas realizadas nas maiores empresas brasileiras pelos autores: Khoury (1999, Beuren e Roedel (2002 e Azevedo, Santos e Pamplona (2004. Dos 115 questionários enviados aos hospitais universitários, 34 foram respondidos. O estudo levou a conclusões importantes, como: Os sistemas de custos atuais dos hospitais têm poucas condições de fornecer informações úteis à gestão; o Custeio ABC é bastante conhecido no ambiente, mas o número de usuários ainda é relativamente pequeno: apenas 15% da amostra; mas existe expectativa por parte de 44% dos hospitais com relação ao uso futuro da abordagem. As principais causas apresentadas para a não-utilização do Sistema ABC foram: (a o sistema utilizado atende às necessidades da organização e (b o Custeio Baseado em Atividades é muito complexo.The Cost Based Activity has been a promising alternative to deal with the complexity that characterizes hospital costs. In the last ten years, only in the Plataforma Lattes, more than a hundred studies of this nature had been found. This work aims to find out, empirically, the use of ABC Costing in Brazilian university hospitals and to compare the results, according to the possibilities, with the researches that have been made in the biggest Brazilian companies by the authors: Khoury (1999, Beuren and Roedel (2002 and Azevedo, Santos and Pamplona (2004. A hundred and fifteen questionnaires were sent to the university hospitals, 34 had been answered. The study relates important

Socio-Environmental and Hematological Profile of Landfill Residents (São Jorge Landfill–Sao Paulo, Brazil

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Vivianni Palmeira Wanderley

2017-01-01

Full Text Available We are experiencing an unprecedented urbanization process that, alongside physical, social and economic developments, has been having a significant impact on a population’s health. Due to the increase in pollution, violence and poverty, our modern cities no longer ensure a good quality of life so they become unhealthy environments. This study aims to assess the effect of social, environmental and economic factors on the hematologic profile of residents of Santo André’s landfill. In particular, we will assess the effect of social, economic, and environmental factors on current and potential disease markers obtained from hematological tests. The research method is the observational type, from a retrospective cohort, and by convenience sampling in Santo André in the Greater ABC (municipalities of Santo André, São Bernardo do Campo and São Caetano do Sul, southeast part of the Greater São Paulo Metropolitan Area, Brazil. The study determined a socio-environmental profile and the hematologic diseases screening related to a close location to the landfill. The disease manifests itself within a broad spectrum of symptoms that causes changes in blood count parameters. The objective of this work is to show that there is an association between social, environmental and economic factors and a variety of serious disease outcomes that may be detected from blood screening. A causal study of the effect of living near the landfill on these disease outcomes would be a very expensive and time-consuming study. This work we believe is sufficient for public health officials to consider policy and attempt remediation of the effects of living near a landfill.

Remediation Technology of Contaminated Areas with Organochlorines: A Preliminary Evaluation Seeking Potential Applications on the Site of Street Capua, Santo André - SP

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Mauro Silva Ruiz

2012-12-01

Full Text Available This paper is aimed to analyze the use of remediation technologies for areas contaminated with organochlorine based on a literature review and discussions with specialists. The remediation technologies analyzed were bioremediation, phytoremediation, nanotechnology, chemical oxidation, and thermal desorption. The purpose is to identify and compare “key problems” for each of these technologies envisaging the use of one or more of these them f or the remediation of the Capua Street site in Santo André, SP. Four databases were used in the preliminary literature review: Scopus, SciELO, Web of Science, and Science Direct. A survey questionnaire was designed to gather information on publications of scientific papers and patents, specific uses of these technologies by companies, and cases of application. Since the quality of the data and information obtained from this questionnaire application was not satisfactory, a new research approach for complementing them was undertaken. For this purpose, the Web of Science was selected as the most adequate data basis to carry out this second survey. However, it was realized that even for this database - that is reference for evaluating academic institutions, researchers and maturity of technologies – bias coming from the original data source can affect the survey results. Moreover, as the number of keywords used in the research consisted of generic terms for each technology, it can also be assumed that if some authors have used very specific terms, a small amount of work published by them would possibly have been misrepresented in the final result.

Relação entre situação social e crescimento físico, numa população infantil de Santo André, SP, Brasil Relationship between social situation and physical growth in children from Santo Andre, State of S. Paulo, Brazil

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Maria Stella Ferreira Levy

1977-09-01

Full Text Available Baseado em dados sócio-antropológicos e em medidas antropométricas coletados no Município de Santo André, Estado de São Paulo, Brasil, foi analisada a população infantil de ambos os sexos e de treze idades diferentes (0, 3, 6 e 9 meses, 1 ano, 1 ano e meio, 2 a 8 anos. Foram utilizadas 3 variáveis independentes ISSE - índice de situação sócio-econômica da família (baseado nas inter-relações da média de gasto familiar mensal "per capita" e a instrução e ocupação do chefe da casa; CATANCES - construída a partir da informação sobre a nacionalidade dos ascendentes das crianças até 3ª geração; e Tamanho do Grupo Residencial. Como variáveis dependentes, utilizou-se a estatura, o peso e o Índice de Kaup. Considerando a relação positiva entre melhores condições de vida e desenvolvimento físico, constatou-se (através do teste de ordenação de médias de Duncan que, embora as médias das medidas diferissem segundo as variáveis independentes, isso não acontecia igualmente nas mesmas idades e nos dois sexos. Observou-se pelos resultados das análises de variância, na maioria das vezes significantes, que as variáveis selecionadas explicavam muito pouco da variação das medidas nas várias idades e sexos. Conclui-se que a amostra estudada, segundo as variáveis independentes deste estudo, difere entre idades em ambos os sexos. Isto levanta uma série de questões sobre quais as variáveis mais adequadas a estudos desse gênero. Sugere-se, consideradas as duas categorias de variável CATANCES, a utilização de duas "tabela padrão" para peso e altura, segundo regiões brasileiras. Quanto ao índice de Kaup, evidenciou-se a necessidade de ser encontrada uma função matemática específica para cada idade, uma vez que, ao menos em relação a crianças em crescimento, o índice não media aquilo a que se propunha.This article was based on some of the data collected in the county of Santo André, State of Sew Paulo

Andres Noormets - olemuselt luuletaja, vormilt lavastaja / Andres Noormets ; intervjueerinud Tiiu Laks

Index Scriptorium Estoniae

Noormets, Andres, 1963-

2010-01-01

Andres Noormets endast, oma lavastustest, näitlemisest ja lavastamisest, elu mõttest, uue otsimisest oma teatritöödega, sellest, mis endiselt paelub teatris ja praegusi teatritegemisi enim mõjutab, ise kirjutamisest jm. Andres Noormetsa eluloolisi andmeid

Continuous infusion of amphotericin B: preliminary experience at Faculdade de Medicina da Fundação ABC.

Science.gov (United States)

Uehara, Roberto Palermo; Sá, Victor Hugo Lara de; Koshimura, Erika Tae; Prudente, Fernanda Vilas Boas; Tucunduva, Luciana Tomanik Cardozo de Mello; Gonçalves, Marina Sahade; Samano, Eliana Sueco Tibana; del Giglio, Auro

2005-09-01

Intravenous amphotericin B deoxycholate (AmB-D) infusions, usually given over 4 hours, frequently induce nephrotoxicity and undesirable infusion-related side effects such as rigors and chills. There is evidence in the literature that the use of AmB-D in the form of continuous 24-hour infusion is less toxic than the usual four-hour infusion of this drug. Our objective was to evaluate the efficacy and safety of continuous infusion of AmB-D for the treatment of persistent fever in neutropenic patients with hematological malignancies after chemotherapy. Observational retrospective analysis of our experience with continuous infusion of AmB-D, at Faculdade de Medicina da Fundação ABC and Hospital Estadual Mário Covas in Santo André. From October 2003 to May 2004, 12 patients with hematological malignancies and chemotherapy-induced neutropenia received 13 cycles of continuous infusion of AmB-D. The median dose of AmB-D was 0.84 mg/kg/day (0.33 to 2.30 mg/kg/day). Concomitant use of nephrotoxic medications occurred in 92% of the cycles. Nephrotoxicity occurred in 30.76% of the cycles, hypokalemia in 16.67%, hepatotoxicity in 30% and adverse infusion-related events in 23%. All patients survived for at least seven days after starting continuous infusion of AmB-D, and clinical resolution occurred in 76% of the cycles. Continuous infusion of AmB-D can be used in our Institution as an alternative to the more toxic four-hour infusion of AmB-D and possibly also as an alternative to the more expensive liposomal formulations of the drug.

Andres Ellamaa : suurperede seostamine asotsiaalsusega mõjub koletislikult / Andres Ellamaa ; interv. Indrek Veiserik

Index Scriptorium Estoniae

Ellamaa, Andres, 1944-

2008-01-01

Vestlus doktor Andres Ellamaaga suurperede toetamisest, kunstlikust viljastamisest. Lisaks: Kuidas kommenteerite dr. Andres Ellamaa 2. juuni Postimehes ilmunud artikli järel tekkinud diskussiooni avalikkuses ja meedias? Kommenteerivad Tallinna Arstide Liidu juhatuse liige Peeter Mardna ja Jõgeva haigla juhataja Peep Põdder

Suursaadik Andres Talvik : Prantsusmaa ei ole euroliidu laienemise pooldaja / Andres Talvik ; interv. Marianne Mikko

Index Scriptorium Estoniae

Talvik, Andres, 1947-

2002-01-01

Eesti suursaadik Prantsusmaal Andres Talvik Prantsusmaa presidendivalimistest, paremäärmuslase Jean-Marie Le Peni pääsemisest selle II vooru, prantslaste vastuseisust EL-i laienemisele, Prantsuse-Saksa suhetest. Andres Talviku elulooandmeid

Hamiltonian ABC

NARCIS (Netherlands)

Meeds, E.; Leenders, R.; Welling, M.; Meila, M.; Heskes, T.

2015-01-01

Approximate Bayesian computation (ABC) is a powerful and elegant framework for performing inference in simulation-based models. However, due to the difficulty in scaling likelihood estimates, ABC remains useful for relatively lowdimensional problems. We introduce Hamiltonian ABC (HABC), a set of

Novas curvas de crescimento da Organização Mundial da Saúde: comparação com valores de crescimento de crianças pré-escolares das cidades de Taubaté e Santo André, São Paulo New World Health Organization growth standards: comparison with growth data of preschool children of the cities of Taubaté and Santo André, São Paulo, Brazil

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Claudio Leone

2009-03-01

Full Text Available OBJETIVO: Em 2007, a Organização Mundial da Saúde (OMS propôs um referencial de crescimento de cinco a 19 anos, a ser utilizado em continuidade ao referencial de menores de cinco anos (de 2006, que, entre outras características, aos cinco anos de idade mostra um bom ajuste com a curva de 2006. Este estudo visa comparar os referenciais da OMS com o crescimento observado em pré-escolares brasileiros. MÉTODOS: A partir dos dados antropométricos de 2.830 crianças com idade entre três e seis anos de duas amostras das cidades de Taubaté e Santo André, em São Paulo, foram calculados os valores dos percentis (P 5, 50 e 95 de peso, estatura e índice de massa corpórea (IMC. Os valores dos novos referenciais da OMS foram comparados a esses resultados de acordo com o sexo e a faixa etária. RESULTADOS: Nos percentis de estatura, o referencial apresentou valores próximos ou pouco superiores aos dos pré-escolares até os cinco anos. Nessa idade, a tendência se inverte, obtendo-se valores progressivamente inferiores até os sete anos. Para peso e IMC, em todas as idades consideradas, o P5 e 50 dos referenciais são pouco menores que os das crianças, mas o P95 indica uma tendência de crescimento progressivamente menor, fazendo com que, próximo aos sete anos, o P95 de IMC dos pré-escolares da amostra seja cerca de 4kg/m² maior. CONCLUSÕES: Os referenciais da OMS apontam uma prevalência menor de magreza (desnutrição e baixa estatura entre cinco e sete anos e, ao mesmo tempo, uma elevação importante da prevalência de obesidade entre três e sete anos de idade.OBJECTIVE: The World Health Organization (WHO, in 2007, proposed a growth reference standard from five to 19 years to be used in continuation to the 2006 one (for children younger than five years-old. This growth chart shows a satisfactory adjustment at five years with the 2006 curve. This study aims to compare WHO references with the growth observed in Brazilian preschool

Policonsumo simultâneo de drogas entre estudantes de graduação da área de ciências da saúde de uma universidade: implicações de gênero, sociais e legais, Santo André - Brasil

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Maria do Perpétuo Socorro de Sousa Nóbrega

2012-01-01

Full Text Available Estudio transversal que busca comprender los patrones de poli-consumo simultáneo de drogas y sus consecuencias de genero, sociales y legales entre estudiantes universitarios. 275 estudiantes de las ciencias de la salud de pregrado de una universidad en Santo André, Brasil participaran en el estudio. El policonsumo simultáneo estuvo presente en 27,9% de los estudiantes de la muestra. Combinaciones: alcohol + marihuana; alcohol + medicamentos de prescripción; alcohol + tabaco + cannabis; tabaco + cannabis; y tabaco + medicamentos de prescripción. Razones: Para relajarse, perder inhibiciones, mantenerse despierto, ayudar a hacer algo que genera molestia y mejorar el efecto de otras sustancias. No se observó asociación entre circunstancias jurídicas y sociales, los hombres presentaron mayor poli-consumo que las mujeres, y la religión se presentó como un factor de protección para el poli-consumo, que fue menor que la encontrada en la literatura. Dado que se trata de futuros profesionales de la salud, las políticas institucionales deben ser analizadas con el fin de reducir la exposición y la vulnerabilidad a estas sustancias psicoactivas.

André Petermann (1922-2011)

CERN Multimedia

2012-01-01

The CERN theory community mourns the loss of André Petermann, one of the first members of the Theory Division, who passed away last August in his 89th year. He pioneered, together with his advisor Stueckelberg, the renormalization group, one of the fundamental ideas in quantum field theory that underlies the modern theory of phase transitions as well as asymptotic freedom and the quest for unification of all the particle interactions.   André was among the very first staff members of CERN, which at the beginning was a small group of theorists at the Niels Bohr Institute in Copenhagen, headed by Bohr himself.  When the group moved to Geneva, they first occupied a set of barracks in Cointrin, next to the airport, before moving to the University of Geneva, and then finally settling on the Meyrin site. André was our last direct contact with our nomadic origins. The importance of André’s early work on the renormalization group was recogn...

Andres Rõhu: kujundaja metsast / Andres Rõhu ; intervjueerinud Kaarel Kressa

Index Scriptorium Estoniae

Rõhu, Andres, 1965-

2010-01-01

Maalikunstnik Andres Rõhu sellest, kuidas temast sai raamatute kujundaja, parematest enda kujundatud raamatutest, südamelähedasematest eesti raamatukujundajatest, maal elamise eelistest. Loetletud A, Rõhu kujundatud teoseid

Isolation and Characterization of the Colletotrichum acutatum ABC Transporter CaABC1

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Suyoung Kim

2014-12-01

Full Text Available Fungi tolerate exposure to various abiotic stresses, including cytotoxic compounds and fungicides, via their ATP-driven efflux pumps belonging to ATP-binding cassette (ABC transporters. To clarify the molecular basis of interaction between the fungus and various abiotic stresses including fungicides, we constructed a cDNA library from germinated conidia of Colletotrichum acutatum, a major anthracnose pathogen of pepper (Capsicum annum L.. Over 1,000 cDNA clones were sequenced, of which single clone exhibited significant nucleotide sequence homology to ABC transporter genes. We isolated three fosmid clones containing the C. acutatum ABC1 (CaABC1 gene in full-length from genomic DNA library screening. The CaABC1 gene consists of 4,059 bp transcript, predicting a 1,353-aa protein. The gene contains the typical ABC signature and Walker A and B motifs. The 5′-flanking region contains a CAAT motif, a TATA box, and a Kozak region. Phylogenetic and structural analysis suggested that the CaABC1 is a typical ABC transporter gene highly conserved in various fungal species, as well as in Chromista, Metazoans, and Viridiplantae. We also found that CaABC1 was up-regulated during conidiation and a minimal medium condition. Moreover, CaABC1 was induced in iprobenfos, kresoxim-methyl, thiophanate-methyl, and hygromycin B. These results demonstrate that CaABC1 is necessary for conidiation, abiotic stress, and various fungicide resistances. These results will provide the basis for further study on the function of ABC transporter genes in C. acutatum.

André Rousset 1930-2001

CERN Multimedia

2001-01-01

André Rousset in 1962 , seen working on BP3, one of the earlier bubble chambers, with André Lagarrigue (standing). André Rousset died on 1 July at the age of 70. For those who lived through the Gargamelle epic, his name is linked with the success of the great bubble chamber that made possible the 1973 discovery of neutral currents. A graduate of Paris's famous Ecole Polytechnique which produced so many great names in particle physics, André Rousset, a native of southern France, joined Louis Leprince-Ringuet's famous laboratory at the Polytechnique in 1954. Among other topics, Rousset played a part in the cosmic ray experiments at the Pic du Midi in the Pyrénées and designed heavy liquid bubble chambers. A Professor at the Ecole des Mines from 1960 onwards, he became deputy director of Louis Leprince-Ringuet's laboratory in 1964. In 1969 he came to CERN where, logically, he headed the TCL group in charge of heavy liquid bubble chambers. In thi...

Evaluation of underground water contamination of tubular wells, by fuels oil in Santo Andre City, Sao Paulo state: a contribution to the environmental management; Avaliacao da contaminacao da agua subterranea de pocos tubulares, por combustiveis fosseis, no municipio de Santo Andre, Sao Paulo: uma contribuicao a gestao ambiental

Energy Technology Data Exchange (ETDEWEB)

Mindrisz, Ana Copat

2006-07-01

The contamination of underground waters by hydrocarbons originated from gas stations has been object of increasing preoccupation in environmental organization all over the world. The organic compounds Benzene, Toluene, Ethylbenzene and Xylene (BTEX), present in these fuels, are extremely toxic to human health and could make impracticable the exploration of these contaminated waters by these kinds of pollutants and consequently the gasoline wells used for this purpose. In this work, it was carried out a diagnosis of the water quality with information and analyses, with the goals to snap shot the situation of the wells destined to domestic and commercial supply of water in the urban area of Santo Andre city, Sao Paulo state. There have been evaluated the presence of micron pollutants BTEX, after contamination due to leaks in fuel storage tanks close to the wells, in different places of the city. The physical chemistry parameters like color, turbidity and residual chlorine were also evaluated as well as trace elements, metals, anions like fluorine, sulphates, chlorine, nitrates and phosphates and bacteriological (total coliforms, thermo stable coliforms, heterotrophic bacteria). On definition of the sampling area, it was sought, at first, the evaluation of environmental contaminations historical series by gas stations, evaluating the set of information available at government environmental organizations and spatial representatively of the problem. For administration of the underground water quality it was adopted the methodology used by Companhia de Tecnologia de Saneamento Ambiental (CETESB), being accomplished a previous identification of contaminated potential areas and organizing a data base on landfills disposal and neglected places; registration of gas station services and, wells used by the population, industrial inventory with active and neglected maps taking into consideration the size and residues generation (such as SEMASA), prioritizing in this way the

Fat embolism after fractures in Duchenne muscular dystrophy: an underdiagnosed complication? A systematic review

Directory of Open Access Journals (Sweden)

Feder D

2017-10-01

Full Text Available David Feder,1 Miriam Eva Koch,1 Beniamino Palmieri,2 Fernando Luiz Affonso Fonseca,1 Alzira Alves de Siqueira Carvalho3 1Pharmacology Department, Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil; 2Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena, Italy; 3Neuroscience Department, Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil Abstract: Duchenne muscular dystrophy is the most frequent lethal genetic disease. Several clinical trials have established both the beneficial effect of steroids in Duchenne muscular dystrophy and the well-known risk of side effects associated with their daily use. For many years it has been known that steroids associated with ambulation loss lead to obesity and also damage the bone structure resulting in the bone density reduction and increased incidence of bone fractures and fat embolism syndrome, an underdiagnosed complication after fractures. Fat embolism syndrome is characterized by consciousness disturbance, respiratory failure and skin rashes. The use of steroids in Duchenne muscular dystrophy may result in vertebral fractures, even without previous trauma. Approximately 25% of patients with Duchenne muscular dystrophy have a long bone fracture, and 1% to 22% of fractures have a chance to develop fat embolism syndrome. As the patients with Duchenne muscular dystrophy have progressive cardiac and respiratory muscle dysfunction, the fat embolism may be unnoticed clinically and may result in increased risk of death and major complications. Different treatments and prevention measures of fat embolism have been proposed; however, so far, there is no efficient therapy. The prevention, early diagnosis and adequate symptomatic treatment are of paramount importance. The fat embolism syndrome should always be considered in patients with Duchenne muscular dystrophy presenting with fractures, or an unexplained and

The use of drugs in patients who have undergone bariatric surgery

Directory of Open Access Journals (Sweden)

Geraldo MSP

2014-05-01

Full Text Available Mariana de Sousa Prado Geraldo,1 Fernando Luiz Affonso Fonseca,2,3 Marisa Regina de Fatima Veiga Gouveia,4 David Feder41Department of Medicine, Faculdade de Medicina do ABC, 2Department of Pharmacy and Biochemistry, Universidade Federal de Sao Paulo, 3Department of Hematology, Faculdade de Medicina do ABC, 4Department of Pharmacology, Faculdade de Medicina do ABC, Santo Andre, SP, Brazil Abstract: According to the World Health Organization, obesity has become an epidemic in the 21st century affecting around 300 million people of all ages worldwide. Clinical treatment modalities for this disease are limited and ineffective when it comes to morbidly obese patients (body mass index – the weight in kilograms divided by height in meters squared – surpasses 40 kg/m2. Therefore, the alternative, surgical treatment, is the best option for these patients, namely gastric restrictive procedures or an intestinal bypass culminating in a malabsorptive syndrome. In the past 20 years, there has been a 70% increase in the number of bariatric procedures all over the world. The main pharmacokinetic consequence observed in the postoperative period of these individuals is a higher or lower absorption of orally administered drugs.Keywords: anatomophysiological alterations, pharmacokinetic, obesity

PT symmetric Aubry–Andre model

International Nuclear Information System (INIS)

Yuce, C.

2014-01-01

PT symmetric Aubry–Andre model describes an array of N coupled optical waveguides with position-dependent gain and loss. We show that the reality of the spectrum depends sensitively on the degree of quasi-periodicity for small number of lattice sites. We obtain the Hofstadter butterfly spectrum and discuss the existence of the phase transition from extended to localized states. We show that rapidly changing periodical gain/loss materials almost conserve the total intensity. - Highlights: • We show that PT symmetric Aubry–Andre model may have real spectrum. • We show that the reality of the spectrum depends sensitively on the degree of disorder. • We obtain the Hofstadter butterfly spectrum for PT symmetric Aubry–Andre model. • We discuss that phase transition from extended to localized states exists

PT symmetric Aubry–Andre model

Energy Technology Data Exchange (ETDEWEB)

Yuce, C., E-mail: cyuce@anadolu.edu.tr

2014-06-13

PT symmetric Aubry–Andre model describes an array of N coupled optical waveguides with position-dependent gain and loss. We show that the reality of the spectrum depends sensitively on the degree of quasi-periodicity for small number of lattice sites. We obtain the Hofstadter butterfly spectrum and discuss the existence of the phase transition from extended to localized states. We show that rapidly changing periodical gain/loss materials almost conserve the total intensity. - Highlights: • We show that PT symmetric Aubry–Andre model may have real spectrum. • We show that the reality of the spectrum depends sensitively on the degree of disorder. • We obtain the Hofstadter butterfly spectrum for PT symmetric Aubry–Andre model. • We discuss that phase transition from extended to localized states exists.

Abc1: a new ABC transporter from the fission yeast Schizosaccharomyces pombe

DEFF Research Database (Denmark)

Christensen, P U; Davis, K; Nielsen, O

1997-01-01

We have isolated the abc1 gene from the fission yeast Schizosaccharomyces pombe. Sequence analysis suggests that the Abc1 protein is a member of the ABC superfamily of transporters and is composed of two structurally homologous halves, each consisting of a hydrophobic region of six transmembrane...

Maailma jalgpallis valitseb nooruslik uljus / Aet Süvari, Veiko Visnapuu

Index Scriptorium Estoniae

Süvari, Aet, 1977-

2007-01-01

Täna õhtul selgub Zürichis rahvusvahelise jalgpalliliidu FIFA galaõhtul, kes on 2007. aasta parim jalgpallur. Sõelale on jäänud kolm meest - Cristiano Ronaldo dos Santos Aveiro, Lionel Andres Messi ja Ricardo Izecson dos Santos Leite

Cloning, characterization and tissue distribution of the rat ATP-binding cassette (ABC) transporter ABC2/ABCA2.

OpenAIRE

Zhao, L X; Zhou, C J; Tanaka, A; Nakata, M; Hirabayashi, T; Amachi, T; Shioda, S; Ueda, K; Inagaki, N

2000-01-01

The ABC1 (ABCA) subfamily of the ATP-binding cassette (ABC) transporter superfamily has a structural feature that distinguishes it from other ABC transporters. Here we report the cloning, molecular characterization and tissue distribution of ABC2/ABCA2, which belongs to the ABC1 subfamily. Rat ABC2 is a protein of 2434 amino acids that has 44.5%, 40.0% and 40.8% identity with mouse ABC1/ABCA1, human ABC3/ABCA3 and human ABCR/ABCA4 respectively. Immunoblot analysis showed that proteins of 260 ...

Andres Puustusmaa esikfilm Moskva filmifestivalil / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2007-01-01

Eestist pärit režissööril Andres Puustusmaal esilinastub 29. juunil Moskva filmifestivali raames tema esimene täispikk mängufilm, Venemaa ja Ukraina ühistöö "Armastuse punane pärl" ("Krasnõi zhemtshug ljubvi"), peaosas Oksana Fandera, operaatoriks soomlane Timo Salminen. Valmis on ka teine mängufilm "1814", mis koos eespool nimetatuga tuleb kinodesse septembris. Ka Moskva festivali kavast

Evaluation of underground water contamination of tubular wells, by fuels oil in Santo Andre City, Sao Paulo state: a contribution to the environmental management

International Nuclear Information System (INIS)

Mindrisz, Ana Copat

2006-01-01

The contamination of underground waters by hydrocarbons originated from gas stations has been object of increasing preoccupation in environmental organization all over the world. The organic compounds Benzene, Toluene, Ethylbenzene and Xylene (BTEX), present in these fuels, are extremely toxic to human health and could make impracticable the exploration of these contaminated waters by these kinds of pollutants and consequently the gasoline wells used for this purpose. In this work, it was carried out a diagnosis of the water quality with information and analyses, with the goals to snap shot the situation of the wells destined to domestic and commercial supply of water in the urban area of Santo Andre city, Sao Paulo state. There have been evaluated the presence of micron pollutants BTEX, after contamination due to leaks in fuel storage tanks close to the wells, in different places of the city. The physical chemistry parameters like color, turbidity and residual chlorine were also evaluated as well as trace elements, metals, anions like fluorine, sulphates, chlorine, nitrates and phosphates and bacteriological (total coliforms, thermo stable coliforms, heterotrophic bacteria). On definition of the sampling area, it was sought, at first, the evaluation of environmental contaminations historical series by gas stations, evaluating the set of information available at government environmental organizations and spatial representatively of the problem. For administration of the underground water quality it was adopted the methodology used by Companhia de Tecnologia de Saneamento Ambiental (CETESB), being accomplished a previous identification of contaminated potential areas and organizing a data base on landfills disposal and neglected places; registration of gas station services and, wells used by the population, industrial inventory with active and neglected maps taking into consideration the size and residues generation (such as SEMASA), prioritizing in this way the

CERN celebrates André Martin’s 80th birthday

CERN Multimedia

2009-01-01

André Martin, pictured at the ceremony held in honour of his 80th birthday. On 27 August 2009 CERN’s Main Auditorium was the venue for a celebration in honour of André Martin’s 80th birthday. Regarded as one of the most important theoretical physicists of his generation, André Martin is one of CERN’s most distinguished figures. The celebration began with a conference, followed by a concert and a reception. After the conference, André Martin made an emotional speech looking back over his fifty-year career and paying tribute to all those who had made important contributions during his time at CERN. "I was extremely happy, and I am very touched by this marvellous celebration you have organised for me. It was a wonderful idea, and I very much enjoyed the concert of Blandine Eynaud and John Devore. My wife, Schu, and I love the music of Gabriel Fauré", he said at the end. André Martin j...

Percepções de graduandos de enfermagem sobre a importância do ato de ouvir na prática assistencial Percepciones de estudiantes de Enfermería sobre la importancia del acto de oír en la práctica asistencial Nursing undergraduate students' view on listening to patients during care delivery

Directory of Open Access Journals (Sweden)

Simone de Oliveira Camillo

2010-03-01

Full Text Available O objetivo deste estudo foi investigar a percepção de graduandos de Enfermagem quanto ao ato de ouvir e sua importância na assistência de enfermagem. Trata-se de um estudo exploratório, com metodologia qualitativa e referencial teórico no Pensamento Complexo de Morin. A investigação foi feita com 12 alunos de enfermagem do último ano, da Faculdade de Medicina do ABC, Santo André-SP. Os dados foram coletados por meio da Técnica de Entrevista Individual em Profundidade, e analisados por meio da Técnica de Análise de Conteúdo. As categorias resultantes foram: O ato de ouvir um desafio para o mundo; As influências do Modelo Biomédico em relação ao ato de ouvir; Pondo de lado ideias pré-concebidas: aprendendo a ouvir; Preparando o graduando de enfermagem para o ato de ouvir. Os resultados demonstram que os discentes consideram que ser um bom ouvinte é algo difícil, pois é preciso estar predisposto a escutar o outro e aprender a suspender ideias pré-concebidas, para não bloquear o que o paciente deseja verbalizar.El objetivo de este estudio fue investigar la percepción de estudiantes de Enfermería respecto del acto de oír y su importancia en la asistencia de enfermería. Se trata de un estudio exploratorio, con metodología cualitativa y referencial teórico en el Pensamiento Complejo de Morin. La investigación fue realizada con doce alumnos de Enfermería cursando su último año en la Faculdade de Medicina do ABC, Santo André, São Paulo, Brasil. Los datos fueron recopilados por medio de la Técnica de la Entrevista Individual en Profundidad, y analizados por medio de la Técnica de Análisis de Contenido. Las categorías resultantes fueron las siguientes: El acto de oír, un desafío para el mundo, Las influencias del Modelo Biomédico en relación al acto de oír, Preparando al estudiante de Enfermería para el acto de oír. Los resultados demostraron que los dicentes consideran que ser un buen oyente es algo dif

Enhancing the ABC Cross

OpenAIRE

Euske, K.J.; Vercio, Alan

2007-01-01

The purpose of the ABC Cross was to portray both a cost and process view of an organization as simply as possible. Unfortunately, the model’s simplified form does not capture the real value of activity-based costing (ABC) for cost accounting that emerged in the mid-1980s. Here we present several ABC models that can help functional and process managers make better decisions.

Andres Ehin Jaapanist Iirini

Index Scriptorium Estoniae

2006-01-01

Andres Ehin valiti Ülemaailmse Haiku Assotsiatsiooni auliikmeks ja kirjaniku inglisekeelset luulekogu "Moose Beetle Swallow" esitleti 2005. aasta Euroopa kultuuripealinnas Corkis Iirimaal. Järgneb: Looming 2006, nr. 2, lk. 311

Sustaining an Effective ABC-ABM System

Directory of Open Access Journals (Sweden)

Gary COKINS

2011-02-01

Full Text Available The purpose of this paper is to describe the Activity- Based Costing (ABC and Activity-Based Management (ABM system and techniques to sustain them as a permanent and repeatable production reporting system, not just for one-off analysis. A comparison is made between ABC/ABM modeling software that extracts source data and business systems that include ABC/ABM modeling features. There are presented the stages of updating, running and rerunning the ABC/ABM system. The resulting information calculated and provided by the ABC/ABM system are analyzed and interpreted in terms of a multidimensional data analysis. The article ends with the authors' conclusions about the benefits of continued operation of sustaining the ABC/ABM system.

Andres Võsand: hakkan ilmselt elukutseliseks kunstnikuks / Andres Võsand ; intervjueerinud Veiko Visnapuu

Index Scriptorium Estoniae

Võsand, Andres, 1966-

2010-01-01

Intervjuu Saksaamaal elava tennisisti Andres Võsandiga, kelle maalinäitus "Värvireisid" on avatud Kadriorus Kastellaanimaja Galeriis 30.10-28.11.2010. Tegelemisest maalikunstiga, näitusest, reisidest inspireeritud loomingust, tööst tennisetreenerina, tennisekarjäärist. Andmeid A. Võsandi elukäigu kohta

ABC at Insteel Industries

OpenAIRE

V.G. Narayanan; Ratna G. Sarkar

1999-01-01

In this paper, we seek to provide empirical documentation of the effect of Activity-Based Costing (ABC) information on product and customer-related decisions made by managers in a company. Proponents of ABC argue that when an entity implements ABC, it reaps at least two important benefits: process improvements that promote more efficient use of resources and hence reduce costs, and a set of overhead cost numbers that, relative to traditional volume-based methods of costing, better represent t...

Comparing the accuracy of ABC and time-driven ABC in complex and dynamic environments: a simulation analysis

OpenAIRE

S. HOOZÉE; M. VANHOUCKE; W. BRUGGEMAN; -

2010-01-01

This paper compares the accuracy of traditional ABC and time-driven ABC in complex and dynamic environments through simulation analysis. First, when unit times in time-driven ABC are known or can be flawlessly estimated, time-driven ABC coincides with the benchmark system and in this case our results show that the overall accuracy of traditional ABC depends on (1) existing capacity utilization, (2) diversity in the actual mix of productive work, and (3) error in the estimated percentage mix. ...

Les mots du jazz. Retour(s) sur Le Jazz, d'André Schaeffner et André Coeuroy

OpenAIRE

Roueff , Olivier

2001-01-01

International audience; Le Jazz by André Schaeffner and André Cœuroy (1926), the first learned analysis of jazz, signaled an important phase in the reinvention of this music in France, since, through the debates it sparked at the time, it helped change jazz’s identity from an « American » to a « Black American » music with African « roots ». Cœuroy and Schaeffner referred to sorts of music that jazz criticism would have throw out of its pantheon, but their analyses would form the major grids ...

Phylogenetic analysis of fungal ABC transporters.

Science.gov (United States)

Kovalchuk, Andriy; Driessen, Arnold J M

2010-03-16

The superfamily of ABC proteins is among the largest known in nature. Its members are mainly, but not exclusively, involved in the transport of a broad range of substrates across biological membranes. Many contribute to multidrug resistance in microbial pathogens and cancer cells. The diversity of ABC proteins in fungi is comparable with those in multicellular animals, but so far fungal ABC proteins have barely been studied. We performed a phylogenetic analysis of the ABC proteins extracted from the genomes of 27 fungal species from 18 orders representing 5 fungal phyla thereby covering the most important groups. Our analysis demonstrated that some of the subfamilies of ABC proteins remained highly conserved in fungi, while others have undergone a remarkable group-specific diversification. Members of the various fungal phyla also differed significantly in the number of ABC proteins found in their genomes, which is especially reduced in the yeast S. cerevisiae and S. pombe. Data obtained during our analysis should contribute to a better understanding of the diversity of the fungal ABC proteins and provide important clues about their possible biological functions.

Sustaining an Effective ABC-ABM System

OpenAIRE

Gary COKINS; Sorinel CĂPUŞNEANU

2011-01-01

The purpose of this paper is to describe the Activity- Based Costing (ABC) and Activity-Based Management (ABM) system and techniques to sustain them as a permanent and repeatable production reporting system, not just for one-off analysis. A comparison is made between ABC/ABM modeling software that extracts source data and business systems that include ABC/ABM modeling features. There are presented the stages of updating, running and rerunning the ABC/ABM system. The resul...

Andres Tali sõnavõtt ettekannete päeval = Andres Tali's speech given on the lecture day / Andres Tali

Index Scriptorium Estoniae

Tali, Andres, 1956-

2006-01-01

Kaasaegse Kunsti Eesti Keskuse ettekannete päev "Kunstnike moraalsed valikud kultuurikonfliktides" 27.04.2006 Tallinna Kunstihoones. Oma installatsioonist "Pastoraalne pastishsh" ning videost "Vägivald ja propaganda - The Movie" samas 8.04.-28.05.2006 avatud Elin Kardi, Marko Mäetamme, Marco Laimre ja Andres Tali ühisnäitusel "Vägivald ja propaganda"

The ABC and AUSSAT.

Science.gov (United States)

McGarritty, Ian

1985-01-01

Discusses the Australian Broadcasting Corporation's (ABC) utilization of the AUSSAT telecommunications satellite to extend its television and radio transmission range to reach remote Australian audiences; the satellite's program gathering and interchange capabilities; and ABC's generation of other benefits to offset cost of satellite services.…

The role of the atypical kinases ABC1K7 and ABC1K8 in abscisic acid responses

Directory of Open Access Journals (Sweden)

Anna eManara

2016-03-01

Full Text Available The ABC1K family of atypical kinases (activity of bc1 complex kinase is represented in bacteria, archaea and eukaryotes. In plants they regulate diverse physiological processes in the chloroplasts and mitochondria, but their precise functions are poorly defined. ABC1K7 and ABC1K8 are probably involved in oxidative stress responses, isoprenyl lipid synthesis and distribution of iron within chloroplasts. Because reactive oxygen species take part in abscisic acid (ABA-mediated processes, we investigated the functions of ABC1K7 and ABC1K8 during germination, stomatal movement and leaf senescence. Both genes were upregulated by ABA treatment and some ABA-responsive physiological processes were affected in abc1k7 and abc1k8 mutants. Germination was more severely affected by ABA, osmotic stress and salt stress in the single and double mutants; the stomatal aperture was smaller in the mutants under standard growth conditions and was not further reduced by exogenous ABA application; ABA-induced senescence symptoms were more severe in the leaves of the single and double mutants compared to wild type leaves. Taken together, our results suggest that ABC1K7 and ABC1K8 might be involved in the cross-talk between ABA and ROS signaling.

Maailmaparandajad / Ole Ry, Susanne Andres

Index Scriptorium Estoniae

Ry, Ole

2012-01-01

Terapeudid Ole Ry ja Susanne Andres räägivad Dr David Berceli loodud TRE (Tension & Trauma Releasing Exercises) harjutuste kasutamise kogemusest erinevate psüühiliste traumade ja pingetega klientide tervise parandamisel

Perceptions of nursing undergraduate students concerning the human dimension in the learning process.

Science.gov (United States)

de Oliveira Camillo, Simone; Lúcia da Silva, Ana; Jefferson do Nascimento, Alan

2007-01-01

This study aimed to identify and interpret the perceptions presented by undergraduate students of a Nursing course after internship in Mental Health. Twelve nursing undergraduate students at the Nursing School of ABC Foundation - Santo André, São Paulo, Brazil were interviewed. These interviews using a semi-structure script were performed and recorded in August 2004. Through Content Analysis, thematic modality, four categories were identified, 1. mental health: providing understanding of the other; 2. respect for the human being: the importance of listening, 3. mental health: contributing for a contextualized view of the patient and 4. nursing graduation: undesirable "signs and symptoms" of the profession. The analysis and the discussion of these categories suggest the possibility of teaching based on the human condition. Thus, we support the idea of new research been carried out, considering that the Mental Health discipline must be valued in the Political and Pedagogical projects of the Nursing Undergraduate Courses.

Diversity and evolution of ABC proteins in basidiomycetes.

Science.gov (United States)

Kovalchuk, Andriy; Lee, Yong-Hwan; Asiegbu, Fred O

2013-01-01

ABC proteins constitute one of the largest families of proteins. They are implicated in wide variety of cellular processes ranging from ribosome biogenesis to multidrug resistance. With the advance of fungal genomics, the number of known fungal ABC proteins increases rapidly but the information on their biological functions remains scarce. In this work we extended the previous analysis of fungal ABC proteins to include recently sequenced species of basidiomycetes. We performed an identification and initial cataloging of ABC proteins from 23 fungal species representing 10 orders within class Agaricomycotina. We identified more than 1000 genes coding for ABC proteins. Comparison of sets of ABC proteins present in basidiomycetes and ascomycetes revealed the existence of two groups of ABC proteins specific for basidiomycetes. Results of survey should contribute to the better understanding of evolution of ABC proteins in fungi and support further experimental work on their characterization.

Bioinformatic survey of ABC transporters in dermatophytes.

Science.gov (United States)

Gadzalski, Marek; Ciesielska, Anita; Stączek, Paweł

2016-01-15

ATP binding cassette (ABC) transporters constitute a very large and ubiquitous superfamily of membrane proteins. They are responsible for ATP hydrolysis driven translocation of countless substrates. Being a very old and diverse group of proteins present in all organisms they share a common feature, which is the presence of an evolutionary conservative nucleotide binding domain (NBD)--the engine that drives the transport. Another common domain is a transmembrane domain (TMD) which consists of several membrane-spanning helices. This part of protein is substrate-specific, thus it is much more variable. ABC transporters are known for driving drug efflux in many pathogens and cancer cells, therefore they are the subject of extensive studies. There are many examples of conferring a drug resistance phenotype in fungal pathogens by ABC transporters, however, little is known about these proteins in dermatophytes--a group of fungi causing superficial mycoses. So far only a single ABC transporter has been extensively studied in this group of pathogens. We analyzed available genomic sequences of seven dermatophyte species in order to provide an insight into dermatophyte ABC protein inventory. Phylogenetic studies of ABC transporter genes and their products were conducted and included ABC transporters of other fungi. Our results show that each dermatophyte genome studied possesses a great variety of ABC transporter genes. Detailed analysis of selected genes and their products indicates that relatively recent duplication of ABC transporter genes could lead to novel substrate specificity. Copyright © 2015 Elsevier B.V. All rights reserved.

Vi har uddelegeret forbruget og nydelsen til Netflix og de andre teknologigiganter

DEFF Research Database (Denmark)

Bak Herrie, Maja

2018-01-01

https://www.information.dk/debat/2018/05/uddelegeret-forbruget-nydelsen-netflix-andre-teknologigiganter......https://www.information.dk/debat/2018/05/uddelegeret-forbruget-nydelsen-netflix-andre-teknologigiganter...

Cafe Lyon = Cafe Lyon / Andres Labi

Index Scriptorium Estoniae

Labi, Andres, 1977-

2013-01-01

Cafe Lyon (Meistri 22, Tallinn) sisekujundusest. Autorid: Janno Roos, Andres Labi, Kristel Jakobson (Ruumilabor). Prantsuse Lütseumi direktori Lauri Leesi arvamus. Disainibüroo Ruumilabor lühitutvustus

The ABC transporters in Candidatus Liberibacter asiaticus.

Science.gov (United States)

Li, Wenlin; Cong, Qian; Pei, Jimin; Kinch, Lisa N; Grishin, Nick V

2012-11-01

Candidatus Liberibacter asiaticus (Ca. L. asiaticus) is a Gram-negative bacterium and the pathogen of Citrus Greening disease (Huanglongbing, HLB). As a parasitic bacterium, Ca. L. asiaticus harbors ABC transporters that play important roles in exchanging chemical compounds between Ca. L. asiaticus and its host. Here, we analyzed all the ABC transporter-related proteins in Ca. L. asiaticus. We identified 14 ABC transporter systems and predicted their structures and substrate specificities. In-depth sequence and structure analysis including multiple sequence alignment, phylogenetic tree reconstruction, and structure comparison further support their function predictions. Our study shows that this bacterium could use these ABC transporters to import metabolites (amino acids and phosphates) and enzyme cofactors (choline, thiamine, iron, manganese, and zinc), resist to organic solvent, heavy metal, and lipid-like drugs, maintain the composition of the outer membrane (OM), and secrete virulence factors. Although the features of most ABC systems could be deduced from the abundant experimental data on their orthologs, we reported several novel observations within ABC system proteins. Moreover, we identified seven nontransport ABC systems that are likely involved in virulence gene expression regulation, transposon excision regulation, and DNA repair. Our analysis reveals several candidates for further studies to understand and control the disease, including the type I virulence factor secretion system and its substrate that are likely related to Ca. L. asiaticus pathogenicity and the ABC transporter systems responsible for bacterial OM biosynthesis that are good drug targets. Copyright © 2012 Wiley Periodicals, Inc.

Enterprise Architecture Data Pada Hotel ABC

OpenAIRE

Soesatyo, Stephanie; Wibowo, Adi; Handojo, Andreas

2015-01-01

Hotel ABC is a company engaged in hospitality management, i.e. room rental, rental of meeting rooms and coffee shop. Hotel ABC has a branch that has the same specifications of the hotel. In business process, Hotel ABC has information systems to support existing business processes. However, existing information systems have not been integrated as a whole. Based on the condition stated above, analysis and design of enterprise architecture information system is created for the company. The proce...

Andres Tolts 60 : omanäoliste vaikelude imeline maailm / Andres Tolts ; intervjueerinud Tiina Kolk ; kommenteerinud Jaan Elken

Index Scriptorium Estoniae

Tolts, Andres, 1949-2014

2009-01-01

Andres Toltsi näitused "Asjad" Hobusepea galeriis 12. oktoobrini, "Näitus" Tallinna Kunstihoones 25. oktoobrini, "Varane Tolts" Haus galeriis 13. novembrini. Pikemalt näitusest "Näitus", kuraator Harry Liivrand

The ABC-paradox: is Time Driven ABC relevant for small and Medium sized enterprises (SME)?

DEFF Research Database (Denmark)

Fladkjær, Henrik Find; Jensen, Erling

Several articles suggest that Activity Based Costing (ABC) has failed to succeed in practical use. It is even argued that we have an ABC-paradox. Activity Based Costing has won theoretically in nu-merous articles in journals, through books, being included in all major Business Accounting text-books...

Perceptions of nursing undergraduate students concerning the human dimension in the learning process Percepciones del alumnos de enfermería sobre la dimensión humana dentro de su aprendizaje Percepções do graduando de enfermagem sobre a dimensão humana no seu aprendizado

Directory of Open Access Journals (Sweden)

Simone de Oliveira Camillo

2007-04-01

Full Text Available This study aimed to identify and interpret the perceptions presented by undergraduate students of a Nursing course after internship in Mental Health. Twelve nursing undergraduate students at the Nursing School of ABC Foundation - Santo André, São Paulo, Brazil were interviewed. These interviews using a semi-structure script were performed and recorded in August 2004. Through Content Analysis, thematic modality, four categories were identified, 1. mental health: providing understanding of the other; 2. respect for the human being: the importance of listening, 3. mental health: contributing for a contextualized view of the patient and 4. nursing graduation: undesirable "signs and symptoms" of the profession. The analysis and the discussion of these categories suggest the possibility of teaching based on the human condition. Thus, we support the idea of new research been carried out, considering that the Mental Health discipline must be valued in the Political and Pedagogical projects of the Nursing Undergraduate Courses.Los objetivos de este estudio fueron identificar e interpretar las percepciones de los alumnos de Graduación de Enfermería posteriores a las prácticas de Salud Mental. Fueron grabadas 12 entrevistas con alumnos de Enfermería de la Facultad de la Fundación ABC - Santo André, São Paulo, Brasil, en agosto de 2004, utilizándose para ello, una guía semi-estructurada. El Análisis de Contenido, en su modalidad temática fue empleada para la identificación de cuatro categorías temáticas: 1. salud mental: proporcionando la comprensión del otro; 2. respeto por lo humano: la importancia de escuchar; 3. salud mental: contribución en la visión en el contexto del paciente y 4. graduación en enfermería: "signos y síntomas" indeseados por la profesión. Del análisis y la discusión de esas categorías se vislumbró la posibilidad de una enseñanza basada en la condición humana. De esa forma, se defiende la idea de que nuevos

Geim, Prof. Sir Andre Konstantin

Indian Academy of Sciences (India)

Fellow Profile. Elected: 2015 Honorary. Geim, Prof. Sir Andre Konstantin FRS. Date of birth: 21 October 1958. Address: Royal Society Research Professor, University of Manchester, Oxford Road, Manchester M13 9PL, UK Contact: Office: (+44-161) 275 4120. Email: geim@manchester.ac.uk. YouTube; Twitter; Facebook ...

Karakteristik og vurdering af Time-Driven Activity-Based Costing på baggrund af ABC’s udvikling

DEFF Research Database (Denmark)

Israelsen, Poul; Kristensen, Thomas Borup

2015-01-01

Artiklen giver en beskrivelse af Activity Based Costings udvikling i fire varianter. Disse benyttes som grundlag for at karakterisere og vurdere de ændringer, som foretages i Time-Driven ABC (TDABC). Det konkluderes at TDABC i nogle tilfælde griber tilbage til omkostningskalkulation forud for ABC......’s tilblivelse (f.eks. homogene afdelinger i stedet for aktiviteter), i andre tilfælde til ABC’s oprindelse (f.eks. brug af transaktionsdrivere i stedet for mere sofistikerede drivere), og på andre områder til metoder uden for ABC’s normale anvendelse (f.eks. “standard variable costing”). Alt i alt argumenteres...

El naturalista Alejando de Humboldt, Cavanilles y Juan Andrés

Directory of Open Access Journals (Sweden)

María-Rosario MARTÍ MARCO

2009-11-01

Full Text Available RESUMEN: Tras una breve introducción en la que se traza un paralelismo entre el erudito Juan Andrés y el naturalista Alejandro de Humboldt, se presenta una síntesis de la relevancia del viaje científico de Humboldt iniciado en España. Las referencias sobre la figura y trabajo de Humboldt y, en menor medida, sobre Cavanilles en la gran obra total de Andrés demuestran el vigor intelectual de éste, quien subraya muchos de los elementos fundamentales del legado humboldtiano.ABSTRACT: This paper begins with a brief introduction to the similarities between the scholar Juan Andrés and the naturalist Alexander von Humboldt and continues with a summary of the relevance of Humboldt’s scientific expedition which began in Spain. The references to Humboldt’s persona and endeavours, and to a lesser extent to Cavanilles, in all of Andrés’ great works demonstrate the intellectual ability of the author who pinpoints many of the fundamental aspects of Humboldt’s legacy.

Los santos patronos de los migrantes Mexicanos a Estados Unidos

Directory of Open Access Journals (Sweden)

Rafael Alarcón

Full Text Available La mayor parte los migrantes mexicanos indocumentados que buscan encontrar un empleo en Estados Unidos son católicos, por esta razón, han incorporado a la devoción de los santos patronos sus tribulaciones que incluyen el trayecto desde sus comunidades de origen a la frontera norte, los peligros del cruce indocumentado, la búsqueda de trabajo y la posible deportación. El objetivo central de este artículo es analizar las características más importantes de tres devociones de los migrantes indocumentados en Tijuana, Baja California, México: Santo Toribio Romo, el "Santo Pollero" que fue canonizado en 2000, el Beato Juan Bautista Scalabrini, fundador de los Misioneros Scalabrinianos y Juan Soldado quien surgió de la religiosidad popular.

Los grabados exteriores de Santo Adriano (Tuñón. Santo Adriano. Asturias

Directory of Open Access Journals (Sweden)

F.J. Fortea Pérez

2005-01-01

Full Text Available En este trabajo se dan a conocer los grabados exteriores de la cueva de Santo Adriano, que se comparan con grabados del mismo tipo existentes en la Región Cantábrica, a lo largo de una franja territorial de 220 km, entre las cuencas de los ríos Nalón al oeste y el Asón al este.

Export of recombinant proteins in Escherichia coli using ABC transporter with an attached lipase ABC transporter recognition domain (LARD

Directory of Open Access Journals (Sweden)

Moon Yuseok

2009-01-01

Full Text Available Abstract Background ATP binding cassette (ABC transporter secretes the protein through inner and outer membranes simultaneously in gram negative bacteria. Thermostable lipase (TliA of Pseudomonas fluorescens SIK W1 is secreted through the ABC transporter. TliA has four glycine-rich repeats (GGXGXD in its C-terminus, which appear in many ABC transporter-secreted proteins. From a homology model of TliA derived from the structure of P. aeruginosa alkaline protease (AprA, lipase ABC transporter domains (LARDs were designed for the secretion of fusion proteins. Results The LARDs included four glycine-rich repeats comprising a β-roll structure, and were added to the C-terminus of test proteins. Either Pro-Gly linker or Factor Xa site was added between fusion proteins and LARDs. We attached different length of LARDs such as LARD0, LARD1 or whole TliA (the longest LARD to three types of proteins; green fluorescent protein (GFP, epidermal growth factor (EGF and cytoplasmic transduction peptide (CTP. These fusion proteins were expressed in Escherichia coli together with ABC transporter of either P. fluorescens or Erwinia chrysanthemi. Export of fusion proteins with the whole TliA through the ABC transporter was evident on the basis of lipase enzymatic activity. Upon supplementation of E. coli with ABC transporter, GFP-LARDs and EGF-LARDs were excreted into the culture supernatant. Conclusion The LARDs or whole TliA were attached to C-termini of model proteins and enabled the export of the model proteins such as GFP and EGF in E. coli supplemented with ABC transporter. These results open the possibility for the extracellular production of recombinant proteins in Pseudomonas using LARDs or TliA as a C-terminal signal sequence.

Graafikatriennaali peapreemia Andres Talile

Index Scriptorium Estoniae

2001-01-01

Tallinna XII graafikatriennaali preemiad: grand prix - Andres Tali; 3 võrdset preemiat - Janne Laine, Leonards Laganovskis, Peeter Laurits; diplomid - Lynne Allen, Lucrecia Urbano, Vladimir Tshaika, Zora Stanè, Endi Poskovic, Päivikki Kallio; EKM preemia - Tif Bitmap; Tallinna linna preemia - Ülle Marks ja Jüri Kass; eripreemiad: - J. Laine (Eesti Pank), Vive Tolli (Paletti Eesti AS), Martins Ratniksh, Juris Boiko, T. Bitmap (Balteco AS). Žürii koosseis

abc: An extensible AspectJ compiler

DEFF Research Database (Denmark)

Avgustinov, Pavel; Christensen, Aske Simon; Hendren, Laurie

2005-01-01

checking and code generation, as well as data flow and control flow analyses. The AspectBench Compiler (abc) is an implementation of such a workbench. The base version of abc implements the full AspectJ language. Its frontend is built, using the Polyglot framework, as a modular extension of the Java...... language. The use of Polyglot gives flexibility of syntax and type checking. The backend is built using the Soot framework, to give modular code generation and analyses. In this paper, we outline the design of abc, focusing mostly on how the design supports extensibility. We then provide a general overview...

Implementation of ABC method in real company

OpenAIRE

Kazhimova, Dina

2014-01-01

The aim of this Bachelor thesis is a thorough analysis of the modern calculation method Activity-based costing (ABC), that identifies the activities that a firm performs, and then assigns indirect costs to products. An ABC system recognizes the relationship between costs, activities and products, and through this relationship assigns indirect costs to products less arbitrarily than traditional methods. Comparison ABC method with traditional methods of cost allocation. Basing on the knowledge ...

Evolutionary Trajectories of Entomopathogenic Fungi ABC Transporters.

Science.gov (United States)

Baral, Bikash

2017-01-01

The ABC protein superfamily-also called traffic ATPases-are energy-dependent ubiquitous proteins, representing one of the crucial and the largest family in the fungal genomes. The ATP-binding cassette endows a characteristic 200-250 amino acids and is omnipresent in all organisms ranging from prokaryotes to eukaryotes. Unlike in bacteria with nutrient import functions, ABC transporters in fungal entomopathogens serve as effective efflux pumps that are largely involved in the shuttle of metabolites across the biological membranes. Thus, the search for ABC proteins may prove of immense importance in elucidating the functional and molecular mechanism at the host-pathogen (insect-fungus) interface. Their sequence homology, domain topology, and functional traits led to the actual identification of nine different families in fungal entomopathogens. Evolutionary relationships within the ABC superfamily are discussed, concentrating on computational approaches for comparative identification of ABC transporters in insect-pathogenic fungi (entomopathogens) with those of animals, plants, and their bacterial orthologs. Ancestors of some fungal candidates have duplicated extensively in some phyla, while others were lost in one lineage or the other, and predictions for the cause of their duplications and/or loss in some phyla are made. ABC transporters of fungal insect-pathogens serve both defensive and offensive functions effective against land-dwelling and ground foraging voracious insects. This study may help to unravel the molecular cascades of ABC proteins to illuminate the means through which insects cope with fungal infection and fungal-related diseases. Copyright © 2017 Elsevier Inc. All rights reserved.

Playware ABC: Engineering Play for Everybody

DEFF Research Database (Denmark)

Lund, Henrik Hautop

2017-01-01

This paper describes the Playware ABC concept, and how it allows anybody, anywhere, anytime to be building bodies and brains, which facilitates users to construct, combine and create. The Playware ABC concept focuses engineering and IT system development on creating solutions that are usable by a...

Igale inimesele oma inspektor? / Andre Nõmm

Index Scriptorium Estoniae

Nõmm, Andre

2007-01-01

Finantsinspektsiooni finantsjärelevalve divisjoni juhataja Andre Nõmm on seisukohal, et finantsinspektsiooni ülesanne ei ole valvata iga kodaniku finantsriski maandamist, vaid vastutust peab kandma iga inimene ise. Ometi on riigi eesmärk tõsta oma kodanike teadlikkust laenuturul valitsevatest ohtudest

André François Boshoff

African Journals Online (AJOL)

Campbell Murn

1945-2016) and pay tribute to him. An only child, André spent most of his childhood in very remote areas of southern Africa due to his magistrate father's various postings. Such locations, for example coastal. Transkei and the Caprivi Strip, instilled ...

An ABC analysis for power generation project

OpenAIRE

Batool Hasani; Younos Vakilalroaia

2013-01-01

One of the primary concerns on performance measurement is to know how much a particular project cost. However, using traditional method on project-based products often leads to inappropriate results. In this paper, we re-examine this issue by comparing the cost of a power station construction project using ABC versus traditional method. The results of survey show that ABC method is capable of providing better estimates for overhead costs compared with traditional method. In other words, ABC m...

Natural gas processing optimization in Espirito Santo plant; Sistema de otimizacao aplicado ao processamento de gas natural no Espirito Santo

Energy Technology Data Exchange (ETDEWEB)

Nunes, Carlos Henrique de Oliveira; Costa, Fernando Lourenco Pinho da; Mazzini, Filipe Ferreira; Campos, Flavia Schittine [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil); Oliveira, Fabricio Carlos; Hamacher, Silvio [Pontificia Univ. Catolica do Rio de Janeiro (PUC-Rio), RJ (Brazil)

2008-07-01

This work introduces the MODEP system, which was developed by PETROBRAS in association with PUC-Rio. The system objective is to support the gas processing and flow planning for the Espirito Santo PETROBRAS. The MODEP core is a non linear optimization model that allows the user to optimize the production of gas as well as to optimize the net present value. In addition, the system offers to the user a comprehensive asset of the gas network since its production fields until the products selling points. The development of this system was motivated by the sharp increase of the Espirito Santo gas production capacity as well as the increase in the number of its processing units. (author)

Costeo ABC - Gestión ABM

OpenAIRE

Cuevas Villegas, Carlos Fernando

2010-01-01

El presente artículo pretende mostrar en forma práctica la problemática de los sistemas actuales de costeo y plantear la alternativa conocida como costeo ABC, sus fundamentos, dificultades y utilidad. Así mismo se enfatiza el uso de la llamada Gerencia ABM, como complemento del costeo ABC.

Viagem(ns a Santos Journey(s to Santos

Directory of Open Access Journals (Sweden)

Henrique Luiz Cukierman

1998-06-01

Full Text Available O artigo busca lançar algumas luzes sobre a construção do laboratório de Manguinhos, recontando um de seus episódios precursores: a viagem a Santos empreendida em 1899 por Oswaldo Cruz, um jovem médico às vésperas de tornar-se herói nacional enquanto símbolo brasileiro da ciência. Destinada a confirmar a chegada pela primeira vez da famigerada peste bubônica em terras brasileiras, a viagem constituiria um marco na justificação da construção de uma fábrica de soro antipestoso no Rio de Janeiro, o futuro Instituto Soroterápico Federal, inaugurado em 1900 e no qual viria a ser instalado o embrião do laboratório de Manguinhos. A partir de quatro narrativas distintas, é possível verificar o processo de ‘criação do mundo’ através do qual cada uma delas realiza sua própria expansão do que seria aparentemente uma ‘mesma’ viagem, permitindo assim configurar a historicidade desses relatos.The article intends to shed some light on the creation of the Manguinhos laboratory by recounting an episode which predates it: the journey to Santos taken in 1899 by Oswaldo Cruz, a young physician about to become a national hero and the Brazilian symbol of science. Destined to confirm the arrival of the infamous bubonic plague in Brazil for the first time, this journey was a milestone in justifying construction of a factory to produce anti-plague serum in Rio de Janeiro - the future Instituto Soroterápico Federal, inaugurated in 1900 and later embryo of the Manguinhos laboratory. Four different narratives of this journey reveal different processes of ‘creating the world’, each arriving at its own interpretation of the same journey.

Tehnikahuviline juht ootab töötajalt ausust / Andres Haamer ; interv. Urve Vilk

Index Scriptorium Estoniae

Haamer, Andres, 1942-

2008-01-01

Overall Eesti nõukogu esimees Andres Haamer vastab oma lapsepõlve, haridusteed, karjääri, AS-i Overalli asutamist, oma tööülesandeid ning ühiskondlikus elus osalemist puudutavatele küsimustele. Kommenteerib Valdo Kalm. Lisa: Andres Haamer; Edu võtmed

Mouse ATP-Binding Cassette (ABC) Transporters Conferring Multi-Drug Resistance

Science.gov (United States)

Shuaizhang, L I; Zhang, Wen; Yin, Xuejiao; Xing, Shilai; Xie, Qunhui; Cao, Zhengyu; Zhao, Bin

2015-04-28

The ABC (ATP-binding cassette) transporter is one of the largest and most ancient protein families with members functioning from protozoa to human. The resistance of cancer and tumor cells to anticancer drugs is due to the over-expression of some ABC transporters, which may finally lead to chemotherapy failure. The mouse ABC transporters are classified into seven subfamilies by phylogenetic analysis. The mouse ABC transporter gene, alias, chromosomal location and function have been determined. Within the ABC super-family, the MDR transporters (Abcb1, Abcc1, Abcg2) in mouse models have been proved to be valuable to investigate the biochemistry and physiological functions. This review concentrates on the multidrug resistance of mouse ABC transporters in cancer and tumor cells.

André B. Muller (25.9.1918-1.4.2006)

Science.gov (United States)

West, R. M.

2006-06-01

With great sadness, we have learned about the death of André Muller on 1 April, at the age of 87. Living in retirement in his native Holland since 1983, he was one of ESOs true pioneers, an outstanding representative of the select group of European astronomers who succeeded in steering ESO through the difficult initial phases. André was close-ly associated with the entire process, from the first site monitoring programmes in South Africa to the subsequent search in Chile, the decision in favour of the La Silla site, as well as the management of ESOs early activities in Chile, includ-ing the construction of the headquarters and observatory and the installation of the first generation of ESO telescopes. Few persons, if any, have been so inti-mately connected to the setting-up of ESOs facilities and it would be impossible to list in detail all of the services André performed for the organisation with such great expertise and zeal during his long career.

Evolutionary relationships of ATP-Binding Cassette (ABC) uptake porters.

Science.gov (United States)

Zheng, Wei Hao; Västermark, Åke; Shlykov, Maksim A; Reddy, Vamsee; Sun, Eric I; Saier, Milton H

2013-05-06

The ATP-Binding Cassette (ABC) functional superfamily includes integral transmembrane exporters that have evolved three times independently, forming three families termed ABC1, ABC2 and ABC3, upon which monophyletic ATPases have been superimposed for energy-coupling purposes [e.g., J Membr Biol 231(1):1-10, 2009]. The goal of the work reported in this communication was to understand how the integral membrane constituents of ABC uptake transporters with different numbers of predicted or established transmembrane segments (TMSs) evolved. In a few cases, high resolution 3-dimensional structures were available, and in these cases, their structures plus primary sequence analyses allowed us to predict evolutionary pathways of origin. All of the 35 currently recognized families of ABC uptake proteins except for one (family 21) were shown to be homologous using quantitative statistical methods. These methods involved using established programs that compare native protein sequences with each other, after having compared each sequence with thousands of its own shuffled sequences, to gain evidence for homology. Topological analyses suggested that these porters contain numbers of TMSs ranging from four or five to twenty. Intragenic duplication events occurred multiple times during the evolution of these porters. They originated from a simple primordial protein containing 3 TMSs which duplicated to 6 TMSs, and then produced porters of the various topologies via insertions, deletions and further duplications. Except for family 21 which proved to be related to ABC1 exporters, they are all related to members of the previously identified ABC2 exporter family. Duplications that occurred in addition to the primordial 3 → 6 duplication included 5 → 10, 6 → 12 and 10 → 20 TMSs. In one case, protein topologies were uncertain as different programs gave discrepant predictions. It could not be concluded with certainty whether a 4 TMS ancestral protein or a 5 TMS ancestral protein

New species and records of Perlidae (Plecoptera) from Espírito Santo State, Brazil.

Science.gov (United States)

Gonçalves, Maísa DE Carvalho; Novaes, Marcos Carneiro; Salles, Frederico Falcão

2017-06-01

Two new species of the perlid genus Anacroneuria, A. rotunda n. sp and A. pitii n. sp are described from Espírito Santo State, Brazil. Additionally, six species of Anacroneuria and four species of Kempnyia are reported for the first time from Espírito Santo State. Records are also provided for A. debilis, A. subcostalis, K. flava, K. gracilenta, and K. neotropica. An undetermined species of Macrogynoplax based on nymphs is also reported from Espírito Santo State.

Forbidden therapies: Santo Daime, ayahuasca, and the prohibition of entheogens in Western society.

Science.gov (United States)

Blainey, Marc G

2015-02-01

Santo Daime, a Brazilian religion organized around a potent psychoactive beverage called ayahuasca, is now being practiced across Europe and North America. Deeming ayahuasca a dangerous "hallucinogen," most Western governments prosecute people who participate in Santo Daime. On the contrary, members of Santo Daime (called "daimistas") consider ayahuasca a medicinal sacrament (or "entheogen"). Empirical studies corroborate daimistas' claim that entheogens are benign and can be beneficial when employed in controlled contexts. Following from anthropology's goal of rendering different cultural logics as mutually explicable, this article intercedes in a misunderstanding between policies of prohibition and an emergent subculture of entheogenic therapy.

Tectonic-stratigraphic evolution of Espirito Santo Basin - Brazil; Evolucao tectono-estratigrafica da Bacia do Espirito Santo

Energy Technology Data Exchange (ETDEWEB)

Silva, Eric Zagotto; Fernandes, Flavio L.; Lobato, Gustavo; Ferreira Neto, Walter Dias [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Coordenacao dos Programas de Pos-graduacao de Engenharia (COPPE). Lab. de Modelagem de Bacias (LAB2M); Petersohn, Eliane [Agencia Nacional do Petroleo, Gas Natural e Biocombustiveis (ANP), Brasilia, DF (Brazil)

2008-07-01

This paper documents the analysis of seismic data of the Espirito Santo basin obtained during the project realized through partnership between COPPE/UFRJ/Lab2M with the Agencia Nacional do Petroleo, Gas Natural e Biocombustiveis (ANP) during 2006 and 2007. The major objective of the seismic data interpretation in the project was to define the main structural and stratigraphic features in order to build a sedimentation model and a tectonic-stratigraphic evolution model of the Espirito Santo basin. Thus, the sedimentary package has been divided into eight genetic units (UN), grouped into five third order stratigraphic sequences, namely: UN-B, represented by siliciclastics rocks of the rift stage and evaporitic sag-rift stage, deposited during the Aptian; UN-C, which represents the carbonatic rocks deposited in a marine environment, and siliciclastics rocks located in the proximal portions during the Albian; and UN-D, represented by sediments, composed mainly by pelites, deposited in between the Cenomanian and Recent, and includes the Eocene volcanic event, which one changed the sedimentation pattern of the basin. (author)

Interview to Boaventura de Sousa Santos

Science.gov (United States)

Guilherme, Manuela; Dietz, Gunther

2017-01-01

In this interview, Professor Boaventura de Sousa Santos addresses, on the one hand, the process of transnationalisation of universities and the neoliberalisation of the classical model of the European university. On the other hand, he stresses that the recognition of difference and internal pluralism of science, which have pervaded the…

The ABC of ABC : An analysis of attribute-based credentials in the light of data protection, privacy and identity.

NARCIS (Netherlands)

Korenhof, P.E.I.; Koning, Merel; Alpár, Gergely; Hoepman, J.H.; Padullés, Joan Balcells; i Martínez, Agustí Cerrillo; Poch, Miquel Peguera; López, Ismael Peña; de Moner, María José Pifarré; Solana, Mònica Vilasau

2014-01-01

Our networked society increasingly needs secure identity sys- tems. The Attribute-based credential (ABC) technology is designed to be privacy-friendlier than contemporary authentication methods, which often suffer from information leakage. So far, however, some of the wider implications of ABC have

Andres Sütevaka näitus Stockholmis

Index Scriptorium Estoniae

2000-01-01

Sütevaka Andrese abstraktsete maalide näitus Stockholmi Eesti Majas. Sütevaka Andres ja näituse avamisele sõitnud tema loomingu kollektsionäär Matti Milius kohtusid Moderna Museeti direktori David Elliotiga teadvustamaks Tartu ja Pärnu kunstielu.

"Vettpidavad allikad" = "Watertight sources" / Janno Roos, Andres Labi

Index Scriptorium Estoniae

Roos, Janno, 1976-

2013-01-01

Eesti Ajaloomuuseumis avatud näituse kujundasid Janno Roos ja Andres Labi (Ruumilabor). Kuraator Krista Sarv. Graafiline disain: Identity. Eksponeeritud allveeuuringute käigus leitu. Arhitektuuriajaloolase Leele Välja arvamus

ABCE1 is a highly conserved RNA silencing suppressor.

Directory of Open Access Journals (Sweden)

Kairi Kärblane

Full Text Available ATP-binding cassette sub-family E member 1 (ABCE1 is a highly conserved protein among eukaryotes and archaea. Recent studies have identified ABCE1 as a ribosome-recycling factor important for translation termination in mammalian cells, yeast and also archaea. Here we report another conserved function of ABCE1. We have previously described AtRLI2, the homolog of ABCE1 in the plant Arabidopsis thaliana, as an endogenous suppressor of RNA silencing. In this study we show that this function is conserved: human ABCE1 is able to suppress RNA silencing in Nicotiana benthamiana plants, in mammalian HEK293 cells and in the worm Caenorhabditis elegans. Using co-immunoprecipitation and mass spectrometry, we found a number of potential ABCE1-interacting proteins that might support its function as an endogenous suppressor of RNA interference. The interactor candidates are associated with epigenetic regulation, transcription, RNA processing and mRNA surveillance. In addition, one of the identified proteins is translin, which together with its binding partner TRAX supports RNA interference.

The AbcA Transporter of Staphylococcus aureus Affects Cell Autolysis

Science.gov (United States)

Schrader-Fischer, Gesine; Berger-Bächi, Brigitte

2001-01-01

Increased production of penicillin-binding protein PBP 4 is known to increase peptidoglycan cross-linking and contributes to methicillin resistance in Staphylococcus aureus. The pbp4 gene shares a 400-nucleotide intercistronic region with the divergently transcribed abcA gene, encoding an ATP-binding cassette transporter of unknown function. Our study revealed that methicillin stimulated abcA transcription but had no effects on pbp4 transcription. Analysis of abcA expression in mutants defective for global regulators showed that abcA is under the control of agr. Insertional inactivation of abcA by an erythromycin resistance determinant did not influence pbp4 transcription, nor did it alter resistance to methicillin and other cell wall-directed antibiotics. However, abcA mutants showed spontaneous partial lysis on plates containing subinhibitory concentrations of methicillin due to increased spontaneous autolysis. Since the autolytic zymograms of cell extracts were identical in mutants and parental strains, we postulate an indirect role of AbcA in control of autolytic activities and in protection of the cells against methicillin. PMID:11158733

Ecotoxicological assessment of sediments from the Port of Santos and the disposal sites of dredged material

Directory of Open Access Journals (Sweden)

Eduinetty Ceci P. M. Sousa

2007-06-01

Full Text Available The dredging of sediments from the Santos Channel is necessary to allow the navigation of ships operating in the Port of Santos. The disposal sites for such sediments are situated on the coastal zone, in front of the Santos Bay. The present paper aimed at evaluating the toxicity of sediments collected at the Santos Channel and at the former and current sediment disposal sites. Whole sediment tests with amphipods and elutriate assays with sea-urchin embryos were used. The samples from the Santos Channel were considered the most toxic: all the sediment samples from this area showed toxicity. Moreover, some samples from both former and new sediment disposal sites exhibited toxicity. Therefore, results showed that sediments from the studied areas present evidences of degradation; however, further studies are required to determine relationships between toxicity and contamination. Results also suggested that the disposal of dredged sediments should be re-evaluated.A dragagem dos sedimentos do Canal de Santos é necessária para permitir o trânsito de navios que operam no Porto de Santos. As áreas de disposição do material dragado estão situadas na zona costeira, em frente à Baía de Santos. Este estudo visou avaliar a qualidade dos sedimentos do Canal de Santos e das áreas de disposição atuais e antigas, utilizando testes de toxicidade de sedimento integral com anfípodos e de toxicidade de elutriatos com embriões de ouriço do mar. As amostras do Canal de Santos foram consideradas as mais tóxicas: todas as amostras dessa área foram consideradas significativamente tóxicas. Além disso, algumas amostras das áreas de disposição exibiram toxicidade. Os resultados mostraram, portanto, que os sedimentos apresentam evidências de degradação em sua qualidade, porém novos estudos devem ser conduzidos visando determinar as relações entre contaminação e toxicidade. Os resultados sugerem ainda que a disposição dos sedimentos dragados

Andre on alati tantsida tahtnud / Anu Mõttus

Index Scriptorium Estoniae

Mõttus, Anu

2009-01-01

Koolitantsu maakonnavoorud on peetud. Igast maakonnast pääsevad piirkonnavooru kuni pooled tantsud. Umbes sama edasipääsuprotsent on ka Andre Laine tantsudel, kelle koolitantsu vaimustus algas Kanepi Gümnaasiumi õpilasena ja kes praeguseks on selle gümnaasiumi tantsupedagoog

Dragones, serpientes y cocodrilos infernales en la comedia de santos

OpenAIRE

Gonzalez Fernandez , Luis

2009-01-01

International audience; Se examinan en este artículo algunos casos en los que aparecen dragones, serpientes y cocodrilos vinculados al personaje teatral del demonio en la comedia de santos. El corpus es mayormente calderoniano.; Parcours retraçant dans la comedia de santos (pièces hagiographiques) la présence de monstres tels que les dragons, les serpents et les crocodiles là où il y a une relation spécifique avec le diable. Le corpus examiné porte essentiellement sur les oeuvres de Pedro Cal...

Santo Agostinho e o De excidio urbis Romae sermo

OpenAIRE

Urbano, Carlota

2006-01-01

Na sequência da queda de Roma em 410, Santo Agostinho afirma no sermão que aqui tomamos que Roma não foi destruída. Não faltaram da parte da população pagã as acusações ao cristianismo. Os próprios cristãos estariam confundidos ao assistir à humilhação da cidade que guardava os túmulos dos apóstolos Pedro e Paulo. Santo Agostinho não tarda em responder a estas recriminações e perplexidades, primeiro em textos relativamente breves como os Sermões, para além de algumas referências em cartas, e ...

Diversity and evolution of ABC proteins in mycorrhiza-forming fungi.

Science.gov (United States)

Kovalchuk, Andriy; Kohler, Annegret; Martin, Francis; Asiegbu, Fred O

2015-12-28

Transporter proteins are predicted to have an important role in the mycorrhizal symbiosis, due to the fact that this type of an interaction between plants and fungi requires a continuous nutrient and signalling exchange. ABC transporters are one of the large groups of transporter proteins found both in plants and in fungi. The crucial role of plant ABC transporters in the formation of the mycorrhizal symbiosis has been demonstrated recently. Some of the fungal ABC transporter-encoding genes are also induced during the mycorrhiza formation. However, no experimental evidences of the direct involvement of fungal ABC transporters in this process are available so far. To facilitate the identification of fungal ABC proteins with a potential role in the establishment of the mycorrhizal symbiosis, we have performed an inventory of the ABC protein-encoding genes in the genomes of 25 species of mycorrhiza-forming fungi. We have identified, manually annotated and curated more than 1300 gene models of putative ABC protein-encoding genes. Out of those, more than 1000 models are predicted to encode functional proteins, whereas about 300 models represent gene fragments or putative pseudogenes. We have also performed the phylogenetic analysis of the identified sequences. The sets of ABC proteins in the mycorrhiza-forming species were compared to the related saprotrophic or plant-pathogenic fungal species. Our results demonstrate the high diversity of ABC genes in the genomes of mycorrhiza-forming fungi. Via comparison of transcriptomics data from different species, we have identified candidate groups of ABC transporters that might have a role in the process of the mycorrhiza formation. Results of our inventory will facilitate the identification of fungal transporters with a role in the mycorrhiza formation. We also provide the first data on ABC protein-coding genes for the phylum Glomeromycota and for orders Pezizales, Atheliales, Cantharellales and Sebacinales, contributing to

Polymorphism in ABC transporter genes of Dirofilaria immitis

Directory of Open Access Journals (Sweden)

Thangadurai Mani

2017-08-01

Full Text Available Dirofilaria immitis, a filarial nematode, causes dirofilariasis in dogs, cats and occasionally in humans. Prevention of the disease has been mainly by monthly use of the macrocyclic lactone (ML endectocides during the mosquito transmission season. Recently, ML resistance has been confirmed in D. immitis and therefore, there is a need to find new classes of anthelmintics. One of the mechanisms associated with ML resistance in nematodes has been the possible role of ATP binding cassette (ABC transporters in reducing drug concentrations at receptor sites. ABC transporters, mainly from sub-families B, C and G, may contribute to multidrug resistance (MDR by active efflux of drugs out of the cell. Gene products of ABC transporters may thus serve as the targets for agents that may modulate susceptibility to drugs, by inhibiting drug transport. ABC transporters are believed to be involved in a variety of physiological functions critical to the parasite, such as sterol transport, and therefore may also serve as the target for drugs that can act as anthelmintics on their own. Knowledge of polymorphism in these ABC transporter genes in nematode parasites could provide useful information for the process of drug design. We have identified 15 ABC transporter genes from sub-families A, B, C and G, in D. immitis, by comparative genomic approaches and analyzed them for polymorphism. Whole genome sequencing data from four ML susceptible (SUS and four loss of efficacy (LOE pooled populations were used for single nucleotide polymorphism (SNP genotyping. Out of 231 SNPs identified in those 15 ABC transporter genes, 89 and 75 of them were specific to the SUS or LOE populations, respectively. A few of the SNPs identified may affect gene expression, protein function, substrate specificity or resistance development and may be useful for transporter inhibitor/anthelmintic drug design, or in order to anticipate resistance development. Keywords: Dirofilaria immitis

Sustained Delivery of Chondroitinase ABC from Hydrogel System

Directory of Open Access Journals (Sweden)

Filippo Rossi

2012-03-01

Full Text Available In the injured spinal cord, chondroitin sulfate proteoglycans (CSPGs are the principal responsible of axon growth inhibition and they contribute to regenerative failure, promoting glial scar formation. Chondroitinase ABC (chABC is known for being able to digest proteoglycans, thus degrading glial scar and favoring axonal regrowth. However, its classic administration is invasive, infection-prone and clinically problematic. An agarose-carbomer (AC1 hydrogel, already used in SCI repair strategies, was here investigated as a delivery system capable of an effective chABC administration: the material ability to include chABC within its pores and the possibility to be injected into the target tissue were firstly proved. Subsequently, release kinetic and the maintenance of enzymatic activity were positively assessed: AC1 hydrogel was thus confirmed to be a feasible tool for chABC delivery and a promising device for spinal cord injury topic repair strategies.

Inventory and analysis of ATP-binding cassette (ABC) systems in Brugia malayi.

Science.gov (United States)

Ardelli, B F; Stitt, L E; Tompkins, J B

2010-07-01

ABC systems are one of the largest described protein superfamilies. These systems have a domain organization that may contain 1 or more transmembrane domains (ABC_TM1F) and 1 or 2 ATP-binding domains (ABC_2). The functions (e.g., import, export and DNA repair) of these proteins distinguish the 3 classes of ABC systems. Mining and PCR-based cloning were used to identify 33 putative ABC systems from the Brugia malayi genome. There were 31 class 2 genes, commonly called ABC transporters, and 2 class 3 genes. The ABC transporters were divided into subfamilies. Three belonged to subfamily A, 16 to subfamily B, 5 to subfamily C, 1 to subfamily E and 3 to subfamilies F and G, respectively. None were placed in subfamilies D and H. Similar to other ABC systems, the ABC_2 domain of B. malayi genes was conserved and contained the Walker A and B motifs, the signature sequence/linker region and the switch region with the conserved histidine. The ABC_TM1F domain was less conserved. The relative abundance of ABC systems was quantified using real-time reverse transcription PCR and was significantly higher in female adults of B. malayi than in males and microfilaria, particularly those in subfamilies B and C, which are associated with drug resistance.

Túnel sumergido en la Bahía de Santos-Guarujá (Sao Paulo, Brasil)

OpenAIRE

Málaga Naranjo, Jaime

2016-01-01

La importancia de la ciudad de Santos se basa en su puerto, el más importante de Brasil y el mayor de toda Sudamérica. Es por ello que una buena conexión con otras ciudades cercanas se hace necesaria para mejorar y optimizar el transporte por vía marítima-carretera. En este proyecto nos centraremos en la conexión de las ciudades de Santos y Guarujá, que están separadas por el Estuario de Santos. Actualmente la unión entre estas dos ciudades se realiza mediante un ferry que cruza el Estuar...

Application of multivariate analysis to evaluate the biochemical ...

African Journals Online (AJOL)

Luma Castro de Souza, Glauco André dos Santos Nogueira, Risely Ferraz de Almeida, Leane Castro de Souza, Myriam Galvão, Cândido Ferreira de Oliveira Neto, Tamires Borges de Oliveira, Ismael de Jesus Matos Viégas, Ricardo Shigueru Okumura ...

2623-IJBCS-Article-Gadji Alahou André

African Journals Online (AJOL)

hp

1. Alahou André Gabazé GADJI1,2*, Ossey Bernard YAPO1, Kouabenan ABO2,. Ladji MEITE1, Agnès Eude Yves GNAGNE1, Satinder Kaur BRAR 3 et. Rajeshwar Dayal TYAGI4. 1Laboratoire des Sciences de l'Environnement (LSE), Unité de ...

Dashboard Auditing of Activity-Based Costing (ABC)

OpenAIRE

Sorinel Capusneanu

2009-01-01

This article aims to define the dashboard auditing according to the specifics of Activity-Based Costing method (ABC). It describes the main objectives of dashboard auditing, the criteria that a dashboard auditor should meet and the step-by-step stages of the entire dashboard auditing process according to the Activity-Based Costing method (ABC).

Pomeranchuk Prize awarded to André Martin

CERN Multimedia

Jordan Juras

2010-01-01

Professor André Martin has been awarded the I.Ya.Pomeranchuk Prize 2010, alongside Professor Valentine Zakharov.   André Martin, CERN theorist, pictured at the ceremony held in honour of his 80th birthday (August 2009). Established by the Institute of Theoretical and Experimental Physics (ITEP) in memory of an outstanding scientist Isaak Yakovlevich Pomeranchuk, the prize is awarded for the study of analytic properties of the scattering amplitude; which lead to the Froissart—Martin bound on the cross section growth with energy. The prize comes as a great honor for Martin, who was in fact a good friend of Mr. Pomeranchuk, "I am surprised and delighted to learn that I will be receiving the 2010 Pomeranchuk Prize. I was an admirer of Pomeranchuk and we shared a great friendship. I met with him for the last time in Erevan (Armenia) in 1965. As a good-bye, he told me, 'Analyticity exists'. This is precisely what I proved to earn the prize"....

Jumalaema kiriku kellamees tuli Tartu Toome varemetesse / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2007-01-01

13. juulil esietendus Emajõe Suveteatris "Jumalaema kiriku kellamees". Victor Hugo romaani järgi tegi instseneeringu Urmas Lennuk, lavastaja Andres Dvinjaninov. Mängitakse Tartu Toomkiriku varemetes

An ABC analysis for power generation project

Directory of Open Access Journals (Sweden)

Batool Hasani

2013-07-01

Full Text Available One of the primary concerns on performance measurement is to know how much a particular project cost. However, using traditional method on project-based products often leads to inappropriate results. In this paper, we re-examine this issue by comparing the cost of a power station construction project using ABC versus traditional method. The results of survey show that ABC method is capable of providing better estimates for overhead costs compared with traditional method. In other words, ABC method helps reduce some of the unnecessary overhead cost items and increase on some other cost components. This helps increase the relative efficiency of the system by reducing total cost of project.

Dashboard Auditing of Activity-Based Costing (ABC

Directory of Open Access Journals (Sweden)

Sorinel Capusneanu

2009-03-01

Full Text Available This article aims to define the dashboard auditing according to the specifics of Activity-Based Costing method (ABC. It describes the main objectives of dashboard auditing, the criteria that a dashboard auditor should meet and the step-by-step stages of the entire dashboard auditing process according to the Activity-Based Costing method (ABC.

Mis on looming.org? : elektrooniline heli / Andres Lõo

Index Scriptorium Estoniae

Lõo, Andres

2004-01-01

Võrguajakirjast www.looming.org, kuhu kogutakse infot põhiliselt kahe jaotuse põhjal: muusika ja helieksperimentalism ning kaasaegne kunst, kunsti ja meediaga seonduv. Idee autorid: Hanno Soans ja Andres Lõo. Ilmunud on looming.orgi esimene muusikakogumik "Lilled algebrale"

ABC/2 Method Does not Accurately Predict Cerebral Arteriovenous Malformation Volume.

Science.gov (United States)

Roark, Christopher; Vadlamudi, Venu; Chaudhary, Neeraj; Gemmete, Joseph J; Seinfeld, Joshua; Thompson, B Gregory; Pandey, Aditya S

2018-02-01

Stereotactic radiosurgery (SRS) is a treatment option for cerebral arteriovenous malformations (AVMs) to prevent intracranial hemorrhage. The decision to proceed with SRS is usually based on calculated nidal volume. Physicians commonly use the ABC/2 formula, based on digital subtraction angiography (DSA), when counseling patients for SRS. To determine whether AVM volume calculated using the ABC/2 method on DSA is accurate when compared to the exact volume calculated from thin-cut axial sections used for SRS planning. Retrospective search of neurovascular database to identify AVMs treated with SRS from 1995 to 2015. Maximum nidal diameters in orthogonal planes on DSA images were recorded to determine volume using ABC/2 formula. Nidal target volume was extracted from operative reports of SRS. Volumes were then compared using descriptive statistics and paired t-tests. Ninety intracranial AVMs were identified. Median volume was 4.96 cm3 [interquartile range (IQR) 1.79-8.85] with SRS planning methods and 6.07 cm3 (IQR 1.3-13.6) with ABC/2 methodology. Moderate correlation was seen between SRS and ABC/2 (r = 0.662; P ABC/2 (t = -3.2; P = .002). When AVMs were dichotomized based on ABC/2 volume, significant differences remained (t = 3.1, P = .003 for ABC/2 volume ABC/2 volume > 7 cm3). The ABC/2 method overestimates cerebral AVM volume when compared to volumetric analysis from SRS planning software. For AVMs > 7 cm3, the overestimation is even greater. SRS planning techniques were also significantly different than values derived from equations for cones and cylinders. Copyright © 2017 by the Congress of Neurological Surgeons

African Journal of Biotechnology - Vol 13, No 12 (2014)

African Journals Online (AJOL)

Fertigation of stillage in the culture of brown and golden linseed (Linum usitatissimum) · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Paulo Andre Cremonez, Armin Feiden, Reginaldo Ferreira Santos, Joel Gustavo Teleken, Douglas Bassegio, Filipe Eliazar ...

El patrimonio identitario de la comunidad de San Andrés

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Carlos Córdova Martínez

2006-01-01

Full Text Available La identidad y el patrimonio son elementos recurrentes si se quiere defender la cultura frente a un mundo globalizado. Dicha labor debe realizarse de lo local a lo nacional y viceversa. El trabajo aborda el patrimonio de una pequeña comunidad holguinera, el Consejo Popular de San Andrés, cuyo centro es el poblado homónimo. Con un largo devenir histórico, que se remonta a fines del siglo XVI. San Andrés atesora un rico patrimonio, que puede incluirse fundamentalmente dentro de la cultura campesina.

abc: An Extensible AspectJ Compiler

DEFF Research Database (Denmark)

Avgustinov, Pavel; Christensen, Aske Simon; Hendren, Laurie J.

2006-01-01

checking and code generation, as well as data flow and control flow analyses. The AspectBench Compiler (abc) is an implementation of such a workbench. The base version of abc implements the full AspectJ language. Its front end is built using the Polyglot framework, as a modular extension of the Java...... language. The use of Polyglot gives flexibility of syntax and type checking. The back end is built using the Soot framework, to give modular code generation and analyses. In this paper, we outline the design of abc, focusing mostly on how the design supports extensibility. We then provide a general...

Peaosa nii teatrilaval kui ka kinolinal / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2010-01-01

Natalja Murina-Puustusmaast, kes mängib peaosa Vene Teatri uuslavastuses "Besame mucho", mille Afolf Käis on lavastanud Eduardo de Filippo näidendi "Silinder" järgi, ja Andres Puustusmaa filmis "Rotilõks", mille võtted algavad peagi

Preliminary hydrogeological evaluation of geological units from the Mesa de los Santos, Santander

International Nuclear Information System (INIS)

Diaz, Eliana Jimena; Contreras, Nathalia Maria; Pinto, Jorge Eduardo; Velandia, Francisco; Morales, Carlos Julio; Hincapie, Gloria

2009-01-01

This paper present a preliminary hydrogeological evaluation of La Mesa de Los Santos' lithostratigraphic formations, based on the geological mapping, stratigraphy and inventory of water points. All this is supplemented with the analysis of primary porosity by means of the petrographic study and the secondary porosity related statistically with the quantity of fractures of each formation, as well as opening, interconnection and dip. It is made an approach to hydrogeological potential of the geologic outcropping formations in La Mesa de Los Santos, Department of Santander, from the stratigraphic and petrographic analysis and the structural features of these formations. The Upper Member of Los Santos Formation presents the highest potential because of rock's fracturing, continued by the Lower Member with low primary porosity and half fracturing. Silgara Formation, Granito de Pescadero, Jordan Formation and some sections of the sandy levels of the Rosablanca Formation presents a lowest potential due to its low porosity and low grade of fracturing. Low permeability is presented in the Middle Member of the Los Santos Formation, Paja and Tablazo formations, as well as in sectors of the fore mentioned formations and in the Quaternary deposits.

INTEGRATING ABC AND EVA TO EVALUATE INVESTMENT DECISIONS

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N. Chiadamrong

2017-12-01

Full Text Available The significance of investment is transparent in the world of competitive business. Traditional costing systems in which their emphasizes are for short term savings rather than long term benefits have shown some lacking in providing accurate and reliable cost data for the investment decisions. Activity-based Costing (ABC, which is developed to satisfy some of the weaknesses of the traditional costing systems, can provide valuable insights into the operating processes and come up with more accurate cost data. In this paper, ABC is used to provide significant information for investment decisions. Although, the ABC method provides accurate operating product costs, it does not identify which products are economic valued added creators and so contribute to companies’ wealth. This drawback can be overcome by applying Economic Value Added (EVA. The adoption of ABC and EVA can represent a considerable change in the managerial thinking and to corporate strategies and business performance.

Preconceptual ABC design definition and system configuration layout: Appendix A

International Nuclear Information System (INIS)

1995-03-01

The mission of the ABC system is to destroy as effectively as possible the fissile material inserted into the core without producing any new fissile material. The contents of this report are as follows: operating conditions for the steam-cycle ABC system; flow rates and component dimensions; drawings of the ABC layout; and impact of core design parameters on containment size

Kino, Theater, Fernsehen : André Bazins Publikumstheorie

NARCIS (Netherlands)

Hanich, Julian; Mundhenke, Florian; Weber, Thomas

2017-01-01

What did the great French film theorist André Bazin think of the collective experience in the cinema? What did he write about the influence co-viewers can have on the emotional engagement, the evaluation and the interpretation of a film? In short: What was his audience theory? To be sure, Bazin is

Eesti fond rahastab Vene infotehnoloogiat / Andres Reimer

Index Scriptorium Estoniae

Reimer, Andres

2006-01-01

Martinson Trigon Venture Partners (MTVP) loob uue tarkvarainvesteeringute fondi, mis viib endise NSVL-i alale kuni 780 miljonit krooni, fond võtab sihiks kümmekond uut ettevõtet. MTVP esimese fondi investeeringutest. Fondide juhi Andres Susi selgitusi. Lisa: Martinson Trigon Venture Partners osalusega firmad; Vt. samas: Moskvas pole raha ja geeniused kohtunud

Genome-wide comparative analysis of ABC systems in the Bdellovibrio-and-like organisms.

Science.gov (United States)

Li, Nan; Chen, Huan; Williams, Henry N

2015-05-10

Bdellovibrio-and-like organisms (BALOs) are gram-negative, predatory bacteria with wide variations in genome sizes and GC content and ecological habitats. The ATP-binding cassette (ABC) systems have been identified in several prokaryotes, fungi and plants and have a role in transport of materials in and out of cells and in cellular processes. However, knowledge of the ABC systems of BALOs remains obscure. A total of 269 putative ABC proteins were identified in BALOs. The genes encoding these ABC systems occupy nearly 1.3% of the gene content in freshwater Bdellovibrio strains and about 0.7% in their saltwater counterparts. The proteins found belong to 25 ABC system families based on their structural characteristics and functions. Among these, 16 families function as importers, 6 as exporters and 3 are involved in various cellular processes. Eight of these 25 ABC system families were deduced to be the core set of ABC systems conserved in all BALOs. All Bacteriovorax strains have 28 or less ABC systems. On the contrary, the freshwater Bdellovibrio strains have more ABC systems, typically around 51. In the genome of Bdellovibrio exovorus JSS (CP003537.1), 53 putative ABC systems were detected, representing the highest number among all the BALO genomes examined in this study. Unexpected high numbers of ABC systems involved in cellular processes were found in all BALOs. Phylogenetic analysis suggests that the majority of ABC proteins can be assigned into many separate families with high bootstrap supports (>50%). In this study, a general framework of sequence-structure-function connections for the ABC systems in BALOs was revealed providing novel insights for future investigations. Copyright © 2015 Elsevier B.V. All rights reserved.

ABCs of Being Smart: S Is for Supporting

Science.gov (United States)

Foster, Joanne

2014-01-01

Joanne Foster's article "R We There Yet?" was first published in "Parenting for High Potential" ("PHP") in 2006, which became the springboard for the "ABCs of Being Smart" series of columns. At that time, Foster invited "PHP" readers to think about their own versions of the "ABCs of Being…

A Compute Environment of ABC95 Array Computer Based on Multi-FPGA Chip

Institute of Scientific and Technical Information of China (English)

无

2000-01-01

ABC95 array computer is a multi-function network's computer based on FPGA technology, The multi-function network supports processors conflict-free access data from memory and supports processors access data from processors based on enhanced MESH network.ABC95 instruction's system includes control instructions, scalar instructions, vectors instructions.Mostly net-work instructions are introduced.A programming environment of ABC95 array computer assemble language is designed.A programming environment of ABC95 array computer for VC++ is advanced.It includes load function of ABC95 array computer program and data, store function, run function and so on.Specially, The data type of ABC95 array computer conflict-free access is defined.The results show that these technologies can develop programmer of ABC95 array computer effectively.

O conhecimento sobre morcegos (Chiroptera: Mammalia do estado do Espírito Santo, sudeste do Brasil

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Poliana Mendes

2010-01-01

Full Text Available A Ordem Chiroptera apresenta importância relevante na dinâmica dos ecossistemas, sendo a ordem de mamíferos com maior diversidade de hábitos de vida. Dentre os estados da região Sudeste do Brasil, o Espírito Santo é um dos mais carentes em relação ao conhecimento de morcegos. Este estudo sintetizou o estado do conhecimento sobre quirópteros gerado no Espírito Santo. Para isso, foram catalogados os morcegos depositados no Museu de Biologia Prof. Mello Leitão (MBML, no Laboratório de Estudos de Quirópteros da Universidade Federal do Espírito Santo (LABEQ, Museum of Vertebrate Zoology (MVZ, Royal Ontario Museum (ROM, American Museum of Natural History (AMNH e University of Michigan Museum Zoology (UMMZ. Além disso, foi realizada uma busca por artigos publicados sobre morcegos do Espírito Santo. Foram revistos 49 artigos científicos, realizadas três teses de mestrado e 11 monografias. Considerando as coleções amostradas e artigos publicados totalizam-se 63 espécies de morcegos para o estado, provenientes de 37 dos 78 municípios do Espírito Santo. A maior riqueza de espécies de morcegos foi encontrada nos municípios de Linhares e Santa Teresa, o que é provavelmente reflexo da maior parte dos espécimes depositados nos museus também serem desses municípios. O Espírito Santo apresenta um grande potencial para se encontrar novas ocorrências de espécies, enfatizando a importância da realização de futuros estudos sobre morcegos no estado.The Order Chiroptera plays a vital role in ecosystem dynamics. Among the states of Southeastern Brazil, Espírito Santo State is the one with the least known bat fauna. This study reports on the current state of knowledge on Espírito Santo bats generating this data bank. We have catalogued the bats deposited in the Biology Museum Prof. Mello Leitão (MBML, Laboratory of Bat Studies of the Federal University of Espírito Santo (LABEQ, Museum of Vertebrate Zoology (MVZ, Royal Ontario

CADENA DEL CAFÉ DE LOS SANTOS, COSTA RICA

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Carlos Francisco Carranza

2012-05-01

Full Text Available Resumen La operación de las actividades económicas y su competitividad, analizadas desde una perspectiva de cadenas globales de mercancías, dependen del funcionamiento de los mercados de crédito, tanto nacionales como internacionales. La operación normal de los negocios requiere crédito para fortalecer sus recursos propios y hacer las compras de materia prima, insumos, pago de salarios e inversión. En todos los casos, el crédito puede ser utilizado para mejorar el diseño de productos, impulsar el acceso a nuevos mercados y aumentar la competitividad. A los productores de la región de Los Santos en Costa Rica se les reconoce por innovadores, y al café de la zona por ser un café de altura y de gran calidad. El artículo explora las necesidades de financiamiento de productores, beneficiadores y exportadores de café de Los Santos, sus fuentes de financiamiento y el uso dado a los recursos obtenidos. Entre las necesidades orientadas al mejoramiento de la competitividad se encontraron la renovación de cafetales entre los productores, el mantenimiento de proyectos y tecnología entre los beneficios y la generación de microbeneficios y búsqueda de nichos de mercado entre los exportadores. Abstract From a global commodity chains perspective, economic activities and their competitiveness depend upon the functioning of credit markets, both international and domestic. Current businesses operations require credit to enhance their own resources in order to buy raw material and inputs, pay wages and make investment. Credit may also be used to improve product design, enter new markets and boost competitiveness as a result. High altitude grown coffee from Los Santos, Costa Rica is widely known for its quality, and their growers as innovative. This paper addresses credit needs of coffee growers, processors and exporters in Los Santos, the credit sources they have access to, and the kind of uses the credit is given. Improving competitiveness uses

Mis siis juhtus Andres Lapeteusega? / Õie Orav

Index Scriptorium Estoniae

Orav, Õie

2011-01-01

Režissöör Grigori Kromanovi filmist "Mis juhtus Andres Lapeteusega?" (Tallinnfilm, 1965). Osades: Einari Koppel, Ita Ever, Heino Mandri, Kaljo Kiisk, Uno Loit, Ada Lundver jt. Lühidalt filmi kohta ilmunud arvustustest. Filmi näeb ETV2-s sarjas "Unustatud filmid"

Santos e devotos no império ultramarino português

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Beatriz Catão Cruz Santos

2009-01-01

Full Text Available O artigo faz uma história da coleção de vilancicos de São Gonçalo de Amarante, que integram a Coleção Barbosa Machado na Biblioteca Nacional do Rio de Janeiro e, simultaneamente, apresenta reflexões sobre a relação santo-devoto no Império Ultramarino Português no século XVIII. Os vilancicos são identificados como um gênero retórico poético que evoca o santo e uma prática religiosa que contrastava com outras. Parte-se de uma perspectiva comparativa entre os vilancicos e outras evidências sobre a relação santo-devoto e, em particular, sobre o santo e sua festa na sociedade colonial escravista. O artigo dialoga com a historiografia centrada na noção de Império e com uma bibliografia da História e das Ciências Sociais voltada para a relação santodevoto, a santidade e as festas.The paper produces a story of vilancicos for Saint Gonçalo do Amarante, that are part of the Rio de Janeiro National Library Barbosa Machado Collection and presents reflections on the relation saint-devotees in the Portuguese Overseas Empire during the 18th century. The vilancicos are identified as a rhetoric poetic genre that reminds the saint and a religious practice that contrasted with others. It starts from a comparative perspective between the vilancicos and other evidences about the relation saint-devotee, and in particular, about the saint and his feast in a colonial and proslavery society. The article deals with the historiography centered in the notion of Empire, and with a bibliography of History and Social Sciences pointed to the relation saint-devotee, the holiness and the feasts.

ABC transporters in fish species: a review

Directory of Open Access Journals (Sweden)

Marta eFerreira

2014-07-01

Full Text Available ATP-binding cassette (ABC proteins were first recognized for their role in multidrug resistance (MDR in chemotherapeutic treatments, which is a major impediment for the successful treatment of many forms of malignant tumors in humans. These proteins, highly conserved throughout vertebrate species, were later related to cellular detoxification and accounted as responsible for protecting aquatic organisms from xenobiotic insults in the so-called multixenobiotic resistance mechanism (MXR. In recent years, research on these proteins in aquatic species has highlighted their importance in the detoxification mechanisms in fish thus it is of extreme added value to continue these studies. Several transporters have been pointed out as relevant in the ecotoxicological context associated to the transport of xenobiotics, such as P-glycoproteins (Pgps, multidrug-resistance-associated proteins (MRPs 1-5 and breast resistance associated protein (BCRP. In mammals, several nuclear receptors have been identified as mediators of phase I and II metabolizing enzymes and ABC transporters. In aquatic species, knowledge on co-regulation of detoxification mechanism is scarce and needs to be addressed. The interaction of emergent contaminants, with chemosensitizer potential, with ABC transporters in aquatic organisms can compromise detoxification processes and have population effects and should be studied in more detail. This review intends to summarize the recent advances in research on MXR mechanisms in fish species, focusing in 1 regulation and functioning of ABC proteins; 2 cooperation with phase I and II biotransformation enzymes; and 3 ecotoxicological relevance and information on emergent pollutants with ability to modulate ABC transporters expression and activity. Several lines of evidence are clear suggesting the important role of these transporters in detoxification mechanisms and must be further investigated in fish.

RAPHAEL SAMÚ: Experiências do muralismo no Espírito Santo

OpenAIRE

GONCALVES, M. B.

2014-01-01

A proposta deste estudo é investigar o processo de criação do artista plástico brasileiro Raphael Samú, tendo como recorte sua obra em mosaico mural, mais especificamente o mural presente na entrada da Universidade Federal do Espírito Santo UFES, em Vitória - Espírito Santo. Para tal, investigaremos através dos pressupostos da Crítica Genética e da Crítica Inferencial quais foram os caminhos tomados pelo artista durante a confecção de tal obra, apontando assim a intencionalidade do projet...

ABC versus CAB for cardiopulmonary resuscitation: a prospective, randomized simulator-based trial.

Science.gov (United States)

Marsch, Stephan; Tschan, Franziska; Semmer, Norbert K; Zobrist, Roger; Hunziker, Patrick R; Hunziker, Sabina

2013-09-06

After years of advocating ABC (Airway-Breathing-Circulation), current guidelines of cardiopulmonary resuscitation (CPR) recommend CAB (Circulation-Airway-Breathing). This trial compared ABC with CAB as initial approach to CPR from the arrival of rescuers until the completion of the first resuscitation cycle. 108 teams, consisting of two physicians each, were randomized to receive a graphical display of either the ABC algorithm or the CAB algorithm. Subsequently teams had to treat a simulated cardiac arrest. Data analysis was performed using video recordings obtained during simulations. The primary endpoint was the time to completion of the first resuscitation cycle of 30 compressions and two ventilations. The time to execution of the first resuscitation measure was 32 ± 12 seconds in ABC teams and 25 ± 10 seconds in CAB teams (P = 0.002). 18/53 ABC teams (34%) and none of the 55 CAB teams (P = 0.006) applied more than the recommended two initial rescue breaths which caused a longer duration of the first cycle of 30 compressions and two ventilations in ABC teams (31 ± 13 vs.23 ± 6 sec; P = 0.001). Overall, the time to completion of the first resuscitation cycle was longer in ABC teams (63 ± 17 vs. 48 ± 10 sec; P ABC with an earlier start of CPR and a shorter time to completion of the first 30:2 resuscitation cycle. These findings endorse the change from ABC to CAB in international resuscitation guidelines.

Politseiniku lustlik ABC / Pekka Erelt

Index Scriptorium Estoniae

Erelt, Pekka, 1965-

1999-01-01

Politsei on välja andnud 'Politseiniku ABC', mis antakse igale politseinikule. Karikaturist Heiki Ernits on peaaegu igale taskuraamatu leheküljele joonistanud pildikese mundrimeestest kentsakates situatsioonides.

Optimization of Straight Cylindrical Turning Using Artificial Bee Colony (ABC) Algorithm

Science.gov (United States)

Prasanth, Rajanampalli Seshasai Srinivasa; Hans Raj, Kandikonda

2017-04-01

Artificial bee colony (ABC) algorithm, that mimics the intelligent foraging behavior of honey bees, is increasingly gaining acceptance in the field of process optimization, as it is capable of handling nonlinearity, complexity and uncertainty. Straight cylindrical turning is a complex and nonlinear machining process which involves the selection of appropriate cutting parameters that affect the quality of the workpiece. This paper presents the estimation of optimal cutting parameters of the straight cylindrical turning process using the ABC algorithm. The ABC algorithm is first tested on four benchmark problems of numerical optimization and its performance is compared with genetic algorithm (GA) and ant colony optimization (ACO) algorithm. Results indicate that, the rate of convergence of ABC algorithm is better than GA and ACO. Then, the ABC algorithm is used to predict optimal cutting parameters such as cutting speed, feed rate, depth of cut and tool nose radius to achieve good surface finish. Results indicate that, the ABC algorithm estimated a comparable surface finish when compared with real coded genetic algorithm and differential evolution algorithm.

Instantaneous transport of salt, nutrients, suspended matter and chlorophyll-a in the tropical estuarine system of Santos

Directory of Open Access Journals (Sweden)

Gleyci A. O. Moser

2005-12-01

Full Text Available The contribution of the polluted São Vicente and Santos estuarine channels to the eutrophication of Santos bay was assessed through the quantification of instantaneous transport of salt, dissolved inorganic nitrogen (DIN and phosphate, organic and inorganic matter (OSM and ISM and chlorophyll-a (Chl-a, during dry (austral winter- August/ 1999 and rainy (austral summer- January/2000 seasons. Samplings were carried out during spring and neap tides, in flood and ebb phases, in two transversal sections at the mouths of the São Vicente and Santos channels. Instantaneous transport values generally indicated importation of salt to the estuarine channels, exportation of DIN to the bay, mainly as N-NH4, at a maximum rate of 1155.1 g s-1 during the rainy season; importation of phosphate during the dry season (maximum of 385 g s-1 and exportation of ISM, OSM and Chl-a during periods of greater freshwater discharge. These results demonstrate the great contribution made by the Santos and São Vicente estuaries to the eutrophication of Santos bay, especially in the rainy season.A contribuição dos canais estuarinos de Santos e São Vicente para a eutrofização da baía de Santos foi avaliada quantificando-se o transporte instantâneo de sal, fosfato e nitrogênio inorgânico dissolvido (NID, material em suspensão orgânico (MSO e inorgânico (MSI e clorofila-a, durante a estação seca (inverno austral- Agosto/1999 e chuvosa (verão austral- Janeiro/ 2000. As amostragens foram realizadas em períodos de sizígia e quadratura, durante as marés enchentes e vazantes, nas secções transversais das bocas dos canais de São Vicente e Santos. Os valores de transporte instantâneo obtidos durante o período de amostragem indicaram exportação de NID, principalmente sobre a forma de N-NH4 (valor máximo de 1155,1 g s-1 na estação chuvosa; importação de fosfato durante a estação seca (máximo de 385,6 g s-1 e exportação de MSI, MSO e clorofila-a em per

Application of activity-based costing (ABC) for a Peruvian NGO healthcare provider.

Science.gov (United States)

Waters, H; Abdallah, H; Santillán, D

2001-01-01

This article describes the application of activity-based costing (ABC) to calculate the unit costs of the services for a health care provider in Peru. While traditional costing allocates overhead and indirect costs in proportion to production volume or to direct costs, ABC assigns costs through activities within an organization. ABC uses personnel interviews to determine principal activities and the distribution of individual's time among these activities. Indirect costs are linked to services through time allocation and other tracing methods, and the result is a more accurate estimate of unit costs. The study concludes that applying ABC in a developing country setting is feasible, yielding results that are directly applicable to pricing and management. ABC determines costs for individual clinics, departments and services according to the activities that originate these costs, showing where an organization spends its money. With this information, it is possible to identify services that are generating extra revenue and those operating at a loss, and to calculate cross subsidies across services. ABC also highlights areas in the health care process where efficiency improvements are possible. Conclusions about the ultimate impact of the methodology are not drawn here, since the study was not repeated and changes in utilization patterns and the addition of new clinics affected applicability of the results. A potential constraint to implementing ABC is the availability and organization of cost information. Applying ABC efficiently requires information to be readily available, by cost category and department, since the greatest benefits of ABC come from frequent, systematic application of the methodology in order to monitor efficiency and provide feedback for management. The article concludes with a discussion of the potential applications of ABC in the health sector in developing countries.

Pedagogic Juan Andrés Cué Bada's work (1935-1979

Directory of Open Access Journals (Sweden)

Janet Reinaldo-Delgado

2017-06-01

Full Text Available Juan Andrés Cué Bada was born on November 30, 1908 in the province of Las Tunas. He had an active political participation against Machado and Batista, while he dedicated himself to private education. After the triumph of the Cuban Revolution in 1959 he moved to Santiago de Cuba and in 1962 began his professorial course at the Universidad de Oriente until he died in 1979. Because of the lack of knowledge about his figure and his work as a teacher, this article Intends to explain the pedagogical work of Juan Andrés Cué Bada between the years 1935 and 1979.

Kutseharidust hakkab muutma uus paradigma / André Huigens ; intervjueerinud Veiko Belials

Index Scriptorium Estoniae

Huigens, André

2011-01-01

Intervjuu Luual toimunud rahvusvahelise kutsehariduse alase seminari peaesineja, André Huigensiga, kes on Euroopa kutseõppe arenduskeskuse Cedefop kvalifikatsiooniraamistiku ekspert Hollandi Wellantcollege’ist

MASSIVE QUANTITIES OF PELAGIC Sargassum ON THE SHORES OF SAN ANDRES ISLAND, SOUTHWESTERN CARIBBEAN

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Brigitte GAVIO

2015-01-01

Cantidades masivas de Sargassum pelágicos en las costas de San Andrés Isla, Caribe suroccidental Se reporta la llegada de una biomasa inusual de Sargassum flotante, compuesta por las especies S. fluitans y S. natans, a la costa nororiental de la isla de San Andrés. La época y el tamaño del evento nunca habían sido reportados anteriormente para la isla.

Producción alfarera en Santo Domingo de los Olleros (Huarochirí - Lima

Directory of Open Access Journals (Sweden)

1999-01-01

Full Text Available LA PRODUCTION DE POTERIE À SANTO DOMINGO DE LOS OLLEROS (HUAROCHIRÍ - LIMA. Cet article presente en détails le processus de production de poterie au sein du village de Santo Domingo de los Olleros. Vu ses caractéristiques, ce village est un cas idoine pour réaliser une étude ethnographique sur la céramique avec une perspective archéologique. Les questions sont posées par rapport au contexte dynamique (actuel, néanmoins nous portons notre attention sur les vestiges matériels du processus, c’est à dire ceux qui demeurent : les gisements d’argile, les produits, l’outillage et l’atelier. Este artículo presenta en detalle el proceso de producción alfarera en el pueblo de Santo Domingo de los Olleros. Dadas sus características este poblado resulta un caso idóneo para realizar una etnografía alfarera a partir de una perspectiva arqueológica. Los interrogantes son planteados al contexto dinámico (presente, pero la atención está centrada en las evidencias materiales del proceso, en aquellas que suelen perdurar: los yacimientos arcillosos, los productos, los artefactos y el taller. THE POTTERY’S PRODUCTION IN SANTO DOMINGO DE LOS OLLEROS (HUAROCHIRÍ - LIMA. This article presents in detail the pottery’s production process in the town of Santo Domingo de los Olleros. Due to its characteristics, this little village results a suitable case to make a ceramic etnography with an archaeological perspective. The questions are made to the dinamic context (present but the attention is focused on the material evidences of the process, those that normally remain: the clay sources, the products, the artifacts and the workshop.

The use of active breathing control (ABC) to reduce margin for breathing motion

International Nuclear Information System (INIS)

Wong, John W.; Sharpe, Michael B.; Jaffray, David A.; Kini, Vijay R.; Robertson, John M.; Stromberg, Jannifer S.; Martinez, Alavro A.

1999-01-01

Purpose: For tumors in the thorax and abdomen, reducing the treatment margin for organ motion due to breathing reduces the volume of normal tissues that will be irradiated. A higher dose can be delivered to the target, provided that the risk of marginal misses is not increased. To ensure safe margin reduction, we investigated the feasibility of using active breathing control (ABC) to temporarily immobilize the patient's breathing. Treatment planning and delivery can then be performed at identical ABC conditions with minimal margin for breathing motion. Methods and Materials: An ABC apparatus is constructed consisting of 2 pairs of flow monitor and scissor valve, 1 each to control the inspiration and expiration paths to the patient. The patient breathes through a mouth-piece connected to the ABC apparatus. The respiratory signal is processed continuously, using a personal computer that displays the changing lung volume in real-time. After the patient's breathing pattern becomes stable, the operator activates ABC at a preselected phase in the breathing cycle. Both valves are then closed to immobilize breathing motion. Breathing motion of 12 patients were held with ABC to examine their acceptance of the procedure. The feasibility of applying ABC for treatment was tested in 5 patients by acquiring volumetric scans with a spiral computed tomography (CT) scanner during active breath-hold. Two patients had Hodgkin's disease, 2 had metastatic liver cancer, and 1 had lung cancer. Two intrafraction ABC scans were acquired at the same respiratory phase near the end of normal or deep inspiration. An additional ABC scan near the end of normal expiration was acquired for 2 patients. The ABC scans were also repeated 1 week later for a Hodgkin's patient. In 1 liver patient, ABC scans were acquired at 7 different phases of the breathing cycle to facilitate examination of the liver motion associated with ventilation. Contours of the lungs and livers were outlined when applicable

Frequent down-regulation of ABC transporter genes in prostate cancer.

Science.gov (United States)

Demidenko, Rita; Razanauskas, Deividas; Daniunaite, Kristina; Lazutka, Juozas Rimantas; Jankevicius, Feliksas; Jarmalaite, Sonata

2015-10-12

ATP-binding cassette (ABC) transporters are transmembrane proteins responsible for the efflux of a wide variety of substrates, including steroid metabolites, through the cellular membranes. For better characterization of the role of ABC transporters in prostate cancer (PCa) development, the profile of ABC transporter gene expression was analyzed in PCa and noncancerous prostate tissues (NPT). TaqMan Low Density Array (TLDA) human ABC transporter plates were used for the gene expression profiling in 10 PCa and 6 NPT specimens. ABCB1 transcript level was evaluated in a larger set of PCa cases (N = 78) and NPT (N = 15) by real-time PCR, the same PCa cases were assessed for the gene promoter hypermethylation by methylation-specific PCR. Expression of eight ABC transporter genes (ABCA8, ABCB1, ABCC6, ABCC9, ABCC10, ABCD2, ABCG2, and ABCG4) was significantly down-regulated in PCa as compared to NPT, and only two genes (ABCC4 and ABCG1) were up-regulated. Down-regulation of ABC transporter genes was prevalent in the TMPRSS2-ERG-negative cases. A detailed analysis of ABCB1 expression confirmed TLDA results: a reduced level of the transcript was identified in PCa in comparison to NPT (p = 0.048). Moreover, the TMPRSS2-ERG-negative PCa cases showed significantly lower expression of ABCB1 in comparison to NPT (p = 0.003) or the fusion-positive tumors (p = 0.002). Promoter methylation of ABCB1 predominantly occurred in PCa and was rarely detected in NPT (p ABC transporter genes in PCa, especially in the TMPRSS2-ERG-negative tumors.

Macroalgas submareales de la bahía de Todos Santos, Baja California, México Submareal macroalgae of the Todos Santos Bay, Baja California, Mexico

Directory of Open Access Journals (Sweden)

Raúl Aguilar-Rosas

2010-12-01

Full Text Available Con el fin de identificar y caracterizar la composición de especies de la zona submareal de la bahía de Todos Santos, Baja California, México; se realizaron muestreos de macroalgas marinas bentónicas en 7 sitios durante 1995-2000. Como resultado de 25 buceos Scuba entre 3 y 33 m de profundidad se encontraron 150 especies de macroalgas para el área de estudio; 10 son Chlorophyta, 26 Phaeophyta y 114 Rhodophyta. Del total, 47 son registros nuevos para el área de estudio y 2 de éstos, Faucheocolax attenuata Setchell y Minium parvum R.L. Moe, son nuevos para la flora marina del Pacífico de México. Se incluye una revisión de las investigaciones en las que se han considerado las macroalgas presentes en la bahía de Todos Santos y una discusión sobre la composición de las especies encontradas, su distribución vertical y reproducción, así como sobre las especies epífitas y parásitas del área.In order to identify and characterize the species composition of the subtidal zone of the Todos Santos Bay, Baja California, Mexico, benthic marine macroalgae were sampled at 7 sites from 1995 to 2000. As a result of 25 scuba at derds for the study area, of which Faucheocolax attenuata Setchell and R.L Moe Minium parvum are new to the marine flora of Pacific Mexico. We include a research that consider the macroalpths between 3 and 33 m we found a total of 150 species of macroalgae for the study area, of which 10 are Chlorophyta, 26 Phaeophyta and 114 Rhodophyta; 47 species represent new recogae in the Todos Santos Bay and a discussion on the composition of species found, its vertical distribution and reproduction, particularly the species epiphytes and parasites present in the study area.

Santos estuarine sediments, Brazil - metal and trace element assessment by neutron activation analysis

International Nuclear Information System (INIS)

Amorim, Eduardo P.; Favaro, Deborah I.T.; Berbel, Glaucia; Braga, Elisabete S.

2009-01-01

The Santos estuary system is an intricate pattern of tidal channels and small rivers originating from the adjacent Pre-Cambrian slopes. These two major estuaries share a common area in the upper portion of the region which interacts with each other. The largest harbor in Latin America is located at the eastern outlet of the Santos estuary. This intricate and sensitive ecosystem is highly susceptible to human impact from industrial activities, urban sewage and polluted solid wastes disposal. Due to its high vulnerability CETESB (Environmental Control Agency of the Sao Paulo State) sporadically monitors the contamination levels of water, sediment and marine organisms in this region. The present study reports results concerning the distribution of some major, trace and rare earth elements in the Santos estuarine marine sediments. Thirty two bottom sediment samples (SS0601 to SS0616 (summer) and SW0601 to SW0616 (winter) were collected in this estuary, including regions of Sao Vicente, Santos, Cubatao and Vicente de Carvalho, by a vanVeen sampler in the summer and winter of 2006. Multielemental analysis was carried out by instrumental neutron activation analysis (INAA). The concentration values obtained for As and metals Cr and Zn in the sediment samples were compared to Canadian Council of Minister of the Environment (CCME) oriented values (TEL and PEL values) and are adopted by CETESB. (author)

Santos estuarine sediments, Brazil - metal and trace element assessment by neutron activation analysis

Energy Technology Data Exchange (ETDEWEB)

Amorim, Eduardo P.; Favaro, Deborah I.T., E-mail: ducamorim@yahoo.com.b, E-mail: defavaro@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP) Sao Paulo, SP (Brazil); Berbel, Glaucia; Braga, Elisabete S., E-mail: edsbraga@usp.b [Universidade de Sao Paulo (USP), SP (Brazil). Inst. Oceanografico. Lab. de Nutrientes, Micronutrientes e Tracos nos Oceanos (LABNUT)

2009-07-01

The Santos estuary system is an intricate pattern of tidal channels and small rivers originating from the adjacent Pre-Cambrian slopes. These two major estuaries share a common area in the upper portion of the region which interacts with each other. The largest harbor in Latin America is located at the eastern outlet of the Santos estuary. This intricate and sensitive ecosystem is highly susceptible to human impact from industrial activities, urban sewage and polluted solid wastes disposal. Due to its high vulnerability CETESB (Environmental Control Agency of the Sao Paulo State) sporadically monitors the contamination levels of water, sediment and marine organisms in this region. The present study reports results concerning the distribution of some major, trace and rare earth elements in the Santos estuarine marine sediments. Thirty two bottom sediment samples (SS0601 to SS0616 (summer) and SW0601 to SW0616 (winter) were collected in this estuary, including regions of Sao Vicente, Santos, Cubatao and Vicente de Carvalho, by a vanVeen sampler in the summer and winter of 2006. Multielemental analysis was carried out by instrumental neutron activation analysis (INAA). The concentration values obtained for As and metals Cr and Zn in the sediment samples were compared to Canadian Council of Minister of the Environment (CCME) oriented values (TEL and PEL values) and are adopted by CETESB. (author)

André-Philip Lemke näitus Tallinnas / Mari Laaniste

Index Scriptorium Estoniae

Laaniste, Mari, 1977-

1998-01-01

Saksa kunstniku André-Philip Lemke (1970) näitus "Üks-üks armsa Jumala kasuks" 17. augustist Saksa Kultuuriinstituudis. Tööd on valgele paberile tavalise sinise pastapliiatsiga kirjutatud-joonistatud

Anticipated Benefits of Care (ABC): psychometrics and predictive value in psychiatric disorders.

Science.gov (United States)

Warden, D; Trivedi, M H; Carmody, T J; Gollan, J K; Kashner, T M; Lind, L; Crismon, M L; Rush, A J

2010-06-01

Attitudes and expectations about treatment have been associated with symptomatic outcomes, adherence and utilization in patients with psychiatric disorders. No measure of patients' anticipated benefits of treatment on domains of everyday functioning has previously been available. The Anticipated Benefits of Care (ABC) is a new, 10-item questionnaire used to measure patient expectations about the impact of treatment on domains of everyday functioning. The ABC was collected at baseline in adult out-patients with major depressive disorder (MDD) (n=528), bipolar disorder (n=395) and schizophrenia (n=447) in the Texas Medication Algorithm Project (TMAP). Psychometric properties of the ABC were assessed, and the association of ABC scores with treatment response at 3 months was evaluated. Evaluation of the ABC's internal consistency yielded Cronbach's alpha of 0.90-0.92 for patients across disorders. Factor analysis showed that the ABC was unidimensional for all patients and for patients with each disorder. For patients with MDD, lower anticipated benefits of treatment was associated with less symptom improvement and lower odds of treatment response [odds ratio (OR) 0.72, 95% confidence interval (CI) 0.57-0.87, p=0.0011]. There was no association between ABC and symptom improvement or treatment response for patients with bipolar disorder or schizophrenia, possibly because these patients had modest benefits with treatment. The ABC is the first self-report that measures patient expectations about the benefits of treatment on everyday functioning, filling an important gap in available assessments of attitudes and expectations about treatment. The ABC is simple, easy to use, and has acceptable psychometric properties for use in research or clinical settings.

Object Detection Based on Template Matching through Use of Best-So-Far ABC

Directory of Open Access Journals (Sweden)

Anan Banharnsakun

2014-01-01

Full Text Available Best-so-far ABC is a modified version of the artificial bee colony (ABC algorithm used for optimization tasks. This algorithm is one of the swarm intelligence (SI algorithms proposed in recent literature, in which the results demonstrated that the best-so-far ABC can produce higher quality solutions with faster convergence than either the ordinary ABC or the current state-of-the-art ABC-based algorithm. In this work, we aim to apply the best-so-far ABC-based approach for object detection based on template matching by using the difference between the RGB level histograms corresponding to the target object and the template object as the objective function. Results confirm that the proposed method was successful in both detecting objects and optimizing the time used to reach the solution.

Conservation of mayflies (Insecta, Ephemeroptera in Espírito Santo, southeastern Brazil

Directory of Open Access Journals (Sweden)

Fabiana Criste Massariol

2014-12-01

Full Text Available Conservation of mayflies (Insecta, Ephemeroptera in Espírito Santo, southeastern Brazil. Ephemeroptera exhibits great diversity among bodies of freshwater in the Atlantic Forest, a biome that is suffering from massive human impact. Within this context, the creation of conservation units using biological information is more recommended than economic, cultural, or political criteria. The distribution pattern of 76 Ephemeroptera species was analyzed using the biogeographical methods Parsimony Analysis of Endemicity and Network Analysis Method in order to infer relevant areas for conservation of the mayfly community in Espírito Santo. The results obtained from both analyses were largely congruent, and pointed out four relevant areas for conservation: two in the south of the state, where conservation units or priority areas for conservation are well established; and two in the north, a region in the state where little conservation efforts have been historically done. Therefore, based on our analyses on mayflies, we recommend the expansion of the existing APCs or the creation of new APCs on the north of Espírito Santo.

André François Boshoff (1945-2016)

African Journals Online (AJOL)

Campbell Murn

National Herbarium in Pretoria and at Stellenbosch. In 1974 André was awarded a. BSc (honours) postgraduate degree in Wildlife Management at the. University of Pretoria (Eugène. Marais. Chair of. Wildlife. Management). It was during this period that he developed a greater interest in birds, especially in their conservation ...

Haapsalu Gümnaasiumi võimla = Haapsalu Gymnasium Gym / Andres Alver

Index Scriptorium Estoniae

Alver, Andres, 1953-

2001-01-01

Projekteerija: Alver Trummal Arhitektid OÜ. Arhitektid Andres Alver, Sven Koppel, Tarmo Laht, Ulla Mets. Projekt 1998-1999, hoone valmis 2001. 11 ill.: asendi- ja korruse plaan, pikilõige, välis- ja sisevaated

Kommest Auto ostmisest huvitub ka Hillar Teder / Andres Eilart

Index Scriptorium Estoniae

Eilart, Andres

2008-01-01

Kommest Auto ostmise vastu tunnevad huvi suurärimees Andres Sarri, Rootsis Peugeot' sõidukeid müüv Taani päritolu K. W. Bruun Import ja multimiljonär Hillar Teder, kellele kuulub Audisid müüv Reval Auto

ABC Technology Development Program

International Nuclear Information System (INIS)

1994-01-01

The Accelerator-Based Conversion (ABC) facility will be designed to accomplish the following mission: 'Provide a weapon's grade plutonium disposition capability in a safe, economical, and environmentally sound manner on a prudent schedule for [50] tons of weapon's grade plutonium to be disposed on in [20] years.' This mission is supported by four major objectives: provide a reliable plutonium disposition capability within the next [15] years; provide a level of safety and of safety assurance that meets or exceeds that afforded to the public by modern commercial nuclear power plants; meet or exceed all applicable federal, state, and local regulations or standards for environmental compliance; manage the program in a cost effective manner. The ABC Technology Development Program defines the technology development activities that are required to accomplish this mission. The technology development tasks are related to the following topics: blanket system; vessel systems; reactivity control systems; heat transport system components; energy conversion systems; shutdown heat transport systems components; auxiliary systems; technology demonstrations - large scale experiments

The ABC of handover: impact on shift handover in the emergency department.

Science.gov (United States)

Farhan, Maisse; Brown, Ruth; Vincent, Charles; Woloshynowych, Maria

2012-12-01

A study was undertaken to test the impact of a new tool for shift handover, 'The ABC of Handover', in the emergency department (ED). The impact on shift handover following implementation of this structured tool, the effect on clinical and organisational aspects of the subsequent shift and the opinions of users of this new tool are reported. A prospective observational before and after study was performed to explore the effect of implementing 'The ABC of Handover' on clinical and organisational practice using a questionnaire. 41 handovers were observed before implementation of 'The ABC of Handover' and 42 were observed after. The new tool was successfully implemented and resulted in a change of practice which led to a significant increase in the operational issues mentioned at handover from a mean of 34% to a mean of 86% of essential items with the ABC method. Over the study period, middle-grade staff demonstrated improved situational awareness as they adopted proactive management of operational issues such as staffing or equipment shortages. All participants reported that 'The ABC of Handover' improved handover regardless of the seniority of the doctor giving it, and found the ABC method easy to learn. Successful implementation of 'The ABC of Handover' led to a change of practice in the ED. Improving handover resulted in better organisation of the shift and heightened awareness of potential patient safety issues. The ABC method provides a framework for organising the shift and preparing for events in the subsequent shift.

Europan 7 Eestis : Lasnamäe. Pärnu / Tiit Trummal, Andres Kurg

Index Scriptorium Estoniae

Trummal, Tiit, 1954-

2004-01-01

Võistluse "Äärelinna võimalus, linnalik intensiivsus ja elamise mitmekesisus" Eesti-Rootsi ühisžüriis Eestist Urmas Muru, Tiit Trummal, Andres Kurg. Tallinna Lasnamäe (14 tööd) ja Pärnu (47 tööd) võistlusalast, võitnud tööde arhitektide loetelu ja võitnud töödest. Lasnamäe: I preemia - autor hispaanlane Andres Fernandes Atela, kaasautorid prantslased Mathieu Andrieu ja Iman Morshedi. Pärnu: I preemia - autorid rumeenlane Oana-Maria Bogdan, ameeriklane Susan Kelly Shannon, argentiinlane Laura Vescina, hispaanlased Juny Llach ja Parra Colacios

Frequent down-regulation of ABC transporter genes in prostate cancer

International Nuclear Information System (INIS)

Demidenko, Rita; Razanauskas, Deividas; Daniunaite, Kristina; Lazutka, Juozas Rimantas; Jankevicius, Feliksas; Jarmalaite, Sonata

2015-01-01

ATP-binding cassette (ABC) transporters are transmembrane proteins responsible for the efflux of a wide variety of substrates, including steroid metabolites, through the cellular membranes. For better characterization of the role of ABC transporters in prostate cancer (PCa) development, the profile of ABC transporter gene expression was analyzed in PCa and noncancerous prostate tissues (NPT). TaqMan Low Density Array (TLDA) human ABC transporter plates were used for the gene expression profiling in 10 PCa and 6 NPT specimens. ABCB1 transcript level was evaluated in a larger set of PCa cases (N = 78) and NPT (N = 15) by real-time PCR, the same PCa cases were assessed for the gene promoter hypermethylation by methylation-specific PCR. Expression of eight ABC transporter genes (ABCA8, ABCB1, ABCC6, ABCC9, ABCC10, ABCD2, ABCG2, and ABCG4) was significantly down-regulated in PCa as compared to NPT, and only two genes (ABCC4 and ABCG1) were up-regulated. Down-regulation of ABC transporter genes was prevalent in the TMPRSS2-ERG-negative cases. A detailed analysis of ABCB1 expression confirmed TLDA results: a reduced level of the transcript was identified in PCa in comparison to NPT (p = 0.048). Moreover, the TMPRSS2-ERG-negative PCa cases showed significantly lower expression of ABCB1 in comparison to NPT (p = 0.003) or the fusion-positive tumors (p = 0.002). Promoter methylation of ABCB1 predominantly occurred in PCa and was rarely detected in NPT (p < 0.001). The study suggests frequent down-regulation of the ABC transporter genes in PCa, especially in the TMPRSS2-ERG-negative tumors. The online version of this article (doi:10.1186/s12885-015-1689-8) contains supplementary material, which is available to authorized users

Note on the ABC Conjecture

OpenAIRE

Carella, N. A.

2006-01-01

This note imparts heuristic arguments and theorectical evidences that contradict the abc conjecture over the rational numbers. In addition, the rudimentary datails for transforming this problem into the doimain of equidistribution theory are provided.

ABC optimized RBF network for classification of EEG signal for epileptic seizure identification

Directory of Open Access Journals (Sweden)

Sandeep Kumar Satapathy

2017-03-01

Full Text Available The brain signals usually generate certain electrical signals that can be recorded and analyzed for detection in several brain disorder diseases. These small signals are expressly called as Electroencephalogram (EEG signals. This research work analyzes the epileptic disorder in human brain through EEG signal analysis by integrating the best attributes of Artificial Bee Colony (ABC and radial basis function networks (RBFNNs. We have used Discrete Wavelet Transform (DWT technique for extraction of potential features from the signal. In our study, for classification of these signals, in this paper, the RBFNNs have been trained by a modified version of ABC algorithm. In the modified ABC, the onlooker bees are selected based on binary tournament unlike roulette wheel selection of ABC. Additionally, kernels such as Gaussian, Multi-quadric, and Inverse-multi-quadric are used for measuring the effectiveness of the method in numerous mixtures of healthy segments, seizure-free segments, and seizure segments. Our experimental outcomes confirm that RBFNN with inverse-multi-quadric kernel trained with modified ABC is significantly better than RBFNNs with other kernels trained by ABC and modified ABC.

Abrasive wear behavior of heat-treated ABC-silicon carbide

Energy Technology Data Exchange (ETDEWEB)

Zhang, Xiao Feng; Lee, Gun Y.; Chen, Da; Ritchie, Robert O.; De Jonghe, Lutgard C.

2002-06-17

Hot-pressed silicon carbide, containing aluminum, boron, and carbon additives (ABC-SiC), was subjected to three-body and two-body wear testing using diamond abrasives over a range of sizes. In general, the wear resistance of ABC-SiC, with suitable heat treatment, was superior to that of commercial SiC.

Retrospective analysis of concurrent chemoradiotherapy for head and neck squamous-cell carcinoma: preliminary experience from ABC School of Medicine, Santo Andre, Sao Paulo State, Brazil; Avaliacao retrospectiva do tratamento quimiorradioterapico concomitante em carcinoma epidermoide de cabeca e pescoco: experiencia preliminar da Faculdade de Medicina do ABC, Santo Andre, SP

Energy Technology Data Exchange (ETDEWEB)

Borba Junior, Antonio Freitas [Faculdade de Medicina do ABC, Santo Andre, SP (Brazil). Dept. de Oncologia Clinica; Giglio, Auro del [Faculdade de Medicina do ABC, Santo Andre, SP (Brazil). Dept. de Hematologia e Oncologia]. E-mail: sandrabr@netpoint.com.br; Philbert, Paula Lajolo; Kaliks, Rafael [Faculdade de Medicina do ABC, Santo Andre, SP (Brazil). Hospital de Ensino

2005-07-01

Background: concurrent chemoradiotherapy constitutes an option for head and neck squamous-cell carcinoma (HNSCC) treatment. Although we found a high incidence of this tumor in our population, we do not have so far results reported for the Brazilian population. Methods: medical records from HNSCC patients who ere treated with concurrent chemoradiotherapy between January 2001 to June 2004 were systematically reviewed. Results: twenty-two HNSCC patients were treated with chemoradiotherapy. The median age was 56 years. The primary tumor site was located in the oropharynx in 11, the larynx in 9 and hypopharynx in 2 patients. Most of the patients (86%) presented with stage III or IV disease. 19 (86%) patients were treated with Cisplatin 100 mg/m{sup 2} D1-22-43, and 3 (14%) patients used Cisplatin 20 mg/m{sup 2} weekly, concurrent with radiotherapy. Hematological and renal toxicity grade 3 or higher was seen in 58% and 10% patients, respectively. Eleven patients achieved a complete response and 8 a partial response. Median disease-free survival was 10 months and median overall survival was 25 months. (author)

A burst of ABC genes in the genome of the polyphagous spider mite Tetranychus urticae.

Science.gov (United States)

Dermauw, Wannes; Osborne, Edward John; Clark, Richard M; Grbić, Miodrag; Tirry, Luc; Van Leeuwen, Thomas

2013-05-10

The ABC (ATP-binding cassette) gene superfamily is widespread across all living species. The majority of ABC genes encode ABC transporters, which are membrane-spanning proteins capable of transferring substrates across biological membranes by hydrolyzing ATP. Although ABC transporters have often been associated with resistance to drugs and toxic compounds, within the Arthropoda ABC gene families have only been characterized in detail in several insects and a crustacean. In this study, we report a genome-wide survey and expression analysis of the ABC gene superfamily in the spider mite, Tetranychus urticae, a chelicerate ~ 450 million years diverged from other Arthropod lineages. T. urticae is a major agricultural pest, and is among of the most polyphagous arthropod herbivores known. The species resists a staggering array of toxic plant secondary metabolites, and has developed resistance to all major classes of pesticides in use for its control. We identified 103 ABC genes in the T. urticae genome, the highest number discovered in a metazoan species to date. Within the T. urticae ABC gene set, all members of the eight currently described subfamilies (A to H) were detected. A phylogenetic analysis revealed that the high number of ABC genes in T. urticae is due primarily to lineage-specific expansions of ABC genes within the ABCC, ABCG and ABCH subfamilies. In particular, the ABCC subfamily harbors the highest number of T. urticae ABC genes (39). In a comparative genomic analysis, we found clear orthologous relationships between a subset of T. urticae ABC proteins and ABC proteins in both vertebrates and invertebrates known to be involved in fundamental cellular processes. These included members of the ABCB-half transporters, and the ABCD, ABCE and ABCF families. Furthermore, one-to-one orthologues could be distinguished between T. urticae proteins and human ABCC10, ABCG5 and ABCG8, the Drosophila melanogaster sulfonylurea receptor and ecdysone-regulated transporter E

Andres Puustusmaa - mees nagu jalgratas ehk Seitseteist kevadist hetke enne Moskva rongi väljumist / Andres Puustusmaa ; interv. Margus Mikomägi

Index Scriptorium Estoniae

Puustusmaa, Andres

2008-01-01

Venemaal tegutseva Eestist pärit režissööri Andres Puustusmaa mängufilm "18-14" esilinastub 10. jaanuaril Eestis. Lisaks tõlge filmi tutvustavast tekstist (www.1814.ru) : "Tsarskoje Selo Kõrilõikaja ja lütseumi kasvandikud". Artikkel rubriigis "Teatriküljed 1/25"

A burst of ABC genes in the genome of the polyphagous spider mite Tetranychus urticae

NARCIS (Netherlands)

Dermauw, W.; Osborne, E.J.; Clark, R.M.; Grbić, M.; Tirry, L.; Van Leeuwen, T.

2013-01-01

Background: The ABC (ATP-binding cassette) gene superfamily is widespread across all living species. The majority of ABC genes encode ABC transporters, which are membrane-spanning proteins capable of transferring substrates across biological membranes by hydrolyzing ATP. Although ABC transporters

African Journal of Biotechnology - Vol 15, No 18 (2016)

African Journals Online (AJOL)

Luma Castro de Souza, Mara Regina Moitinho, Risely Ferraz de Almeida, Ellen Gleyce da Silva Lima, Leane Castro de Souza, Myriam Galvão Neves, Cândido Ferreira de Oliveira Neto, Glauco André dos Santos Nogueira, Maria Eunice Lima Rocha, Mayra Taniely Ribeiro Abade, Marlison Tavares Ávila, 731-739 ...

Plan comunicacional para incrementar las ventas y participación de mercado de la empresa ALVESA, ubicada en la ciudad de Santo Domingo, provincia Santo Domingo de los Tsáchilas.

OpenAIRE

Alvarado Muñoz, Héctor Patricio

2017-01-01

Se elaboró un Plan Comunicacional para incrementar las ventas y la participación en el mercado de los productos que distribuye la empresa ALVESA, ubicada de la ciudad de Santo Domingo, provincia Santo Domingo de los Tsáchilas. Se realizó un profundo análisis sobre la situación actual de la empresa para identificar los problemas que afectan los factores antes mencionados, determinándose así que no existe un proceso comunicacional adecuado que posibilite el fortalecimiento de la...

André Lefevere and his Manipulation School

OpenAIRE

Šmrha, Jan

2015-01-01

This theoretical and historiographical thesis examines the theoretical work of the Translation Studies scholar André Lefevere. It focuses primarily on the analysis of Lefevere's work in the context of the development of Translation Studies (particularly in connection with the development of Descriptive Translation Studies, the formation of the "Manipulation School" and the cultural and sociological turns in Translation Studies). The thesis covers Lefevere's theoretical underpinnings, the grad...

MetaABC--an integrated metagenomics platform for data adjustment, binning and clustering.

Science.gov (United States)

Su, Chien-Hao; Hsu, Ming-Tsung; Wang, Tse-Yi; Chiang, Sufeng; Cheng, Jen-Hao; Weng, Francis C; Kao, Cheng-Yan; Wang, Daryi; Tsai, Huai-Kuang

2011-08-15

MetaABC is a metagenomic platform that integrates several binning tools coupled with methods for removing artifacts, analyzing unassigned reads and controlling sampling biases. It allows users to arrive at a better interpretation via series of distinct combinations of analysis tools. After execution, MetaABC provides outputs in various visual formats such as tables, pie and bar charts as well as clustering result diagrams. MetaABC source code and documentation are available at http://bits2.iis.sinica.edu.tw/MetaABC/ CONTACT: dywang@gate.sinica.edu.tw; hktsai@iis.sinica.edu.tw Supplementary data are available at Bioinformatics online.

Eesti Energia esindused = Eesti Energia branches / Andres Labi, Janno Roos

Index Scriptorium Estoniae

Labi, Andres, 1977-

2013-01-01

Eesti Energia klienditeeninduse kontorite sisekujundusest. Autorid: Janno Roos, Andres Labi ja Liisa Põime (Ruumilabor). Visuaalne identiteet: Tank.Teenuste disain: Urmas Pastarus. ESLi aastapreemiate žürii esimehe Kaido Kivi ning žürii liikme Raivo Puusepa arvamused

Phase behavior of model ABC triblock copolymers

Science.gov (United States)

Chatterjee, Joon

The phase behavior of poly(isoprene-b-styrene- b-ethylene oxide) (ISO), a model ABC triblock copolymer has been studied. This class of materials exhibit self-assembly, forming a large array of ordered morphologies at length scales of 5-100 nm. The formation of stable three-dimensionally continuous network morphologies is of special interest in this study. Since these nanostructures considerably impact the material properties, fundamental knowledge for designing ABC systems have high technological importance for realizing applications in the areas of nanofabrication, nanoporous media, separation membranes, drug delivery and high surface area catalysts. A comprehensive framework was developed to describe the phase behavior of the ISO triblock copolymers at weak to intermediate segregation strengths spanning a wide range of composition. Phases were characterized through a combination of characterization techniques, including small angle x-ray scattering, dynamic mechanical spectroscopy, transmission electron microscopy, and birefringence measurements. Combined with previous investigations on ISO, six different stable ordered state symmetries have been identified: lamellae (LAM), Fddd orthorhombic network (O70), double gyroid (Q230), alternating gyroid (Q214), hexagonal (HEX), and body-centered cubic (BCC). The phase map was found to be somewhat asymmetric around the fI = fO isopleth. This work provides a guide for theoretical studies and gives insight into the intricate effects of various parameters on the self-assembly of ABC triblock copolymers. Experimental SAXS data evaluated with a simple scattering intensity model show that local mixing varies continuously across the phase map between states of two- and three-domain segregation. Strategies of blending homopolymers with ISO triblock copolymer were employed for studying the swelling properties of a lamellar state. Results demonstrate that lamellar domains swell or shrink depending upon the type of homopolymer that

Shedding Light on the Sea: André Morel's Legacy to Optical Oceanography

Science.gov (United States)

Antoine, David; Babin, Marcel; Berthon, Jean-François; Bricaud, Annick; Gentili, Bernard; Loisel, Hubert; Maritorena, Stéphane; Stramski, Dariusz

2014-01-01

André Morel (1933-2012) was a prominent pioneer of modern optical oceanography, enabling significant advances in this field. Through his forward thinking and research over more than 40 years, he made key contributions that this field needed to grow and to reach its current status. This article first summarizes his career and then successively covers different aspects of optical oceanography where he made significant contributions, from fundamental work on optical properties of water and particles to global oceanographic applications using satellite ocean color observations. At the end, we share our views on André's legacy to our research field and scientific community.

Perekonnad hoiavad kontrolli tuntud suurfirmade tegevuse üle / Andres Reimer

Index Scriptorium Estoniae

Reimer, Andres

2005-01-01

Andres Haamer räägib oma perefirma Overall Eesti loomisest. Uniprindi-Unipressi omanikud Sirje ja Andrus Reinsoo hindavad koos oma äri peatrumpideks täielikku usaldust ja teineteisemõistmist. Lisad: Maailma legend: Rockefellerid; Eesti legend: Puhkid

Estudo epidemiológico de 55 pacientes portadores de doença vertebral metastática sintomática em Santo André - SP, Brasil Estudio epidemiológico de 55 pacientes con enfermedad metastásica sintomática de la columna vertebral en Santo André - SP, Brasil Epidemiological study of 55 patients with symptomatic metastatic spinal disease in Santo André - SP, Brazil

Directory of Open Access Journals (Sweden)

Edgar Santiago Valesin Filho

2013-01-01

Full Text Available OBJETIVO: Apresentar o perfil epidemiológico dos pacientes portadores de doença vertebral metastática sintomática de serviço público de atenção terciária na região do ABC. MÉTODO: Avaliamos de Janeiro de 2008 a Janeiro de 2011, 55 pacientes com diagnóstico de metástase vertebral e coletamos dados de idade no diagnóstico de lesão metastática, sexo, tipo de tumor, topografia vertebral e sintomatologia. A evolução da doença foi observado nas datas: biópsia da neoplasia primária; início de sintomas vertebrais; diagnóstico de doença vertebral metastática (imagem e data da cirurgia. RESULTADOS: A idade dos pacientes variou de 28 a 85 anos; 40% homens e 60% mulheres. Os principais tumores foram carcinoma de mama (32,7%, mieloma múltiplo (25,4% e carcinoma de próstata (14,5%. Observamos 25 pacientes (45,4% com lesões na coluna torácica; 13 pacientes (23,6% lombares ou sacrais; 11 pacientes (20% difusas e 6 pacientes (10,9% cervicais. 34 pacientes (61,8% apresentavam somente dor, os demais (38,2% apresentavam também alteração neurológica. O intervalo entre a lesão primária e a manifestação clínica de lesão vertebral apresentou mediana de 190 dias; entre a sintomatologia na coluna e o diagnóstico por imagem teve mediana de 70 dias; aos submetidos a cirurgia, entre o diagnóstico e o procedimento foi de 288 dias. CONCLUSÃO: Observamos os dados epidemiológicas, compatíveis a literatura: predomínio do sexo feminino (60%, com idade média de 55 anos; metástases predominantemente toracolombares (69% por neoplasia de mama, mieloma múltiplo e próstata (72%. Observamos ampla variação no intervalo de tempo na descrição cronológica dos eventos clínico-diagnósticos e cirúrgicos.OBJETIVO: Presentar el perfil epidemiológico de los pacientes con síntomas de enfermedad metastásica espinal tratados en el servicio público de atención terciaria en la región del ABC. MÉTODO: Se evaluaron 55 pacientes con diagn

ATP-binding cassette (ABC) transporters in normal and pathological lung

NARCIS (Netherlands)

van der Deen, M; de Vries, EGE; Timens, W; Scheper, RJ; Timmer-Bosscha, H; Postma, DS

2005-01-01

ATP-binding cassette ( ABC) transporters are a family of transmembrane proteins that can transport a wide variety of substrates across biological membranes in an energy-dependent manner. Many ABC transporters such as P-glycoprotein ( P-gp), multidrug resistance-associated protein 1 ( MRP1) and

A Neisseria meningitidis fbpABC mutant is incapable of using nonheme iron for growth.

Science.gov (United States)

Khun, H H; Kirby, S D; Lee, B C

1998-05-01

The neisserial fbpABC locus has been proposed to act as an iron-specific ABC transporter system. To confirm this assigned function, we constructed an fbpABC mutant in Neisseria meningitidis by insertional inactivation of fbpABC with a selectable antibiotic marker. The mutant was unable to use iron supplied from human transferrin, human lactoferrin, or iron chelates. However, the use of iron from heme and human hemoglobin was unimpaired. These results support the obligatory participation of fbpABC in neisserial periplasmic iron transport and do not indicate a role for this genetic locus in the heme iron pathway.

Implementation of the ABC Model in a Company Dealing with Extraction of Raw Materials

Directory of Open Access Journals (Sweden)

Radoslav Bajus

2014-06-01

Full Text Available ABC method is a new system for accurate product pricing, cost analysis of the causes of individual products and their optimization. The prices of products are accurately taken into account according to all relevant overhead costs in their actual context and relationships. Except of product costs, ABC method follows costs regarding customers, suppliers, distribution, transport, manufacturing, operational and security processes, management processes and other business activities. ABC method sees the company as a complex of interrelated activities and processes. ABC method represents more precise cost calculation for the product. The aim of the present article is to highlight the introduction of the ABC method to the enterprise and compare it with the traditional method. The result is to reduce costs by introducing ABC method to the enterprise.

abc: The AspectBench Compiler for AspectJ

DEFF Research Database (Denmark)

Allan, Chris; Avgustinov, Pavel; Christensen, Aske Simon

2005-01-01

abc is an extensible, optimising compiler for AspectJ. It has been designed as a workbench for experimental research in aspect-oriented programming languages and compilers. We outline a programme of research in these areas, and we review how abc can help in achieving those research goals...

Dashboard auditing of ABC (Activity-Based Costing). Theoretical approaches

OpenAIRE

Căpuşneanu, Sorinel/I

2009-01-01

This article aims to define the dashboard auditing according to the specifics of Activity-Based Costing method (ABC). It describes the main objectives of dashboard auditing, the criteria that a dashboard auditor should meet and the step-by-step stages of the entire dashboard auditing process of an enterprise from steel industry according to the Activity-Based Costing method (ABC).

Carbon and oxygen stable isotope data as paleoenvironmental indicators for limestones from the Campos, Santos and Espirito Santo Basins, Brazil

International Nuclear Information System (INIS)

Takaki, T.; Rodrigues, R.

1984-01-01

Carbon and oxygen isotope data of limestones from Campos, Santos and Espirito Santo basins provided additional information on the sedimentation environments of these carbonates. The predominance of δ 13 C values between + 1,0 per mille and - 1,0 per mille samples from the Tertiary and the middle section of the Jiquia Stage (Lower Cretaceous) could indiccate, for both carbonate sequences, deposition in a normal marine environment. However, the absence of marine fossils in the Jiquia Stage but not in the Tertiary allows to suggest a normal marine environment for the latter and saline lakes for the former. More positive δ 13 C values in the upper portion of the Jiquia Stage and in the Alagoas Stage suggest a restricted marine environment, with a tendency to hypersalinity. During the Albian the carbonate sedimentation could have occurred in a marine enrironment with an above normal salinity, as indicated by values of δ 13 C between + 3,0 per mille and + 4,0 per mille. According to δ 18 O data, the surface waters were warm, with a tendency of becoming gradually cooler towards the top of the Tertiary. (Author) [pt

Second-order nonlinear optical metamaterials: ABC-type nanolaminates

International Nuclear Information System (INIS)

Alloatti, L.; Kieninger, C.; Lauermann, M.; Köhnle, K.; Froelich, A.; Wegener, M.; Frenzel, T.; Freude, W.; Leuthold, J.; Koos, C.

2015-01-01

We demonstrate a concept for second-order nonlinear metamaterials that can be obtained from non-metallic centrosymmetric constituents with inherently low optical absorption. The concept is based on iterative atomic-layer deposition of three different materials, A = Al 2 O 3 , B = TiO 2 , and C = HfO 2 . The centrosymmetry of the resulting ABC stack is broken since the ABC and the inverted CBA sequences are not equivalent—a necessary condition for non-zero second-order nonlinearity. In our experiments, we find that the bulk second-order nonlinear susceptibility depends on the density of interfaces, leading to a nonlinear susceptibility of 0.26 pm/V at a wavelength of 800 nm. ABC-type nanolaminates can be deposited on virtually any substrate and offer a promising route towards engineering of second-order optical nonlinearities at both infrared and visible wavelengths

Energy Transition Initiative: Island Energy Snapshot - San Andres and Providencia (Fact Sheet); NREL(National Renewable Energy Laboratory)

Energy Technology Data Exchange (ETDEWEB)

None

2015-03-01

This profile provides a snapshot of the energy landscape of the Archipelago of San Andres, Providencia, and Santa Catalina (unpopulated), also known as San Andres and Providencia, which is equidistant between Costa Rica and Jamaica and 775 kilometers northwest of Colombia. The archipelago is part of Colombia, though Nicaragua has also laid claim to it.

Saberes da ayahuasca e processos educativos na religião do Santo Daime

Directory of Open Access Journals (Sweden)

Maria Betânia B. Albuquerque

2012-01-01

contextos culturales, como en la religión brasileña conocida como Santo Daime. Supongo, por lo que se afirma en los propios himnos de la doctrina, que el Daime (ayahuasca es un profesor y que en la religión se experimenta un proceso educativo donde un conjunto de saberes es distribuido y aprehendido. Metodológicamente, resulta de una búsqueda bibliográfica, documental y de campo. Tiene como fuentes la bibliografía sobre religiones ayahuasqueras, los libros de himnos del Santo Daime y la realización de entrevistas con participantes (daimistas de Brasil y otros países. Teóricamente se inspira en los estudios de Carlos Rodrigues Brandão acerca de la educación como cultura y los escritos de Boaventura de Sousa Santos, restringiendo este texto a la noción de saberes ecológicos y ambientales del autor. Entre los principales saberes del daime resalto: los saberes ecológicos y ambientales, cognitivos, estéticos, medicinales y para la paz.

RELIGIÃO E EDUCAÇÃO: OS SABERES DA AYAHUASCA NO SANTO DAIME

Directory of Open Access Journals (Sweden)

Maria Betânia Barbosa Albuquerque

2011-05-01

Full Text Available O artigo analisa os saberes da ayahuasca, beberagem de origem indígena feita da combinação de um cipó e as folhas de um arbusto da Amazônia, utilizada em diferentes contextos culturais como é o caso da religião brasileira conhecida como Santo Daime. Metodologicamente, o artigo resulta de uma pesquisa bibliográfica, documental e de campo. Tem como fontes a bibliografia sobre as religiões ayahuasqueiras, os cadernos de hinos do Santo Daime e a realização de entrevistas com daimistas do Brasil e outros países. Teoricamente, inspira-se nos estudos de Carlos Rodrigues Brandão acerca da educação como cultura e nos escritos de Boaventura de Sousa Santos, restringindo este texto à noção de “ecologia de saberes” deste autor. Parto do pressuposto de que o daime (ayahuasca é um professor e que na religião vivencia-se um processo educativo no qual um conjunto de saberes é circulado e apreendido. Dentre os principais saberes do

Tectonic-stratigraphic evolution of mini-basins and salt provinces of Espirito Santo Basin-Brazil; Analise da evolucao tectono sedimentar de mini-bacias e provincias de sal da Bacia do Espirito Santo

Energy Technology Data Exchange (ETDEWEB)

Ferreira Neto, Walter Dias; Fernandes, Flavio Luis [Petroleum Geoscience Technology Ltda. (PGT), Rio de Janeiro, RJ (Brazil); Mohriak, Webster [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil); Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, RJ (Brazil)

2008-07-01

The Espirito Santo Basin integrates the group of basins along the eastern Brazilian continental margin. It is located between 18 deg and 21 deg S, encompassing an area of approximately 220,000 km{sup 2}, onshore and offshore the Espirito Santo State. Its geological limit with the Campos Basin to the south is defined by a Precambrian basement high (Vitoria Arch), and its northern limit with the Mucuri Basin is defined by a geopolitical limit. The study of salt tectonics processes in the Espirito Santo Basin allowed the deformational analysis and interpretation of the chronological evolution of the mini-basins developed between salt diapirs. We observe an intrinsic relationship between halokinesis and creation of subsidence troughs that may be important for trapping hydrocarbon reservoirs, and consequently form oil and gas accumulations in this portion of the basin. This geodynamics evolution of these structures is marked by a strong linkage between salt movement and coeval sedimentation in the interdomal basins, forming structures and stratigraphic traps that may constitute important aspects for the petroleum geology. (author)

Raio Piiroja : mängijatest ei suudetud maksimumi pigistada / Andres Kalvik

Index Scriptorium Estoniae

Kalvik, Andres, 1982-

2007-01-01

Vt. ka Postimees : na russkom jazõke 19. nov., lk. 13. Eesti koondis võlgneb EM-valikturniiri viimase kohtumise 2:0 Andorra üle suuresti Andres Operile. Kommenteerib Andorra koondise peatreener David Rodrigo

Miocene and Pleistocene mollusks from San Andres Island (Caribbean Sea, Colombia) and Paleogeographic considerations

International Nuclear Information System (INIS)

Diaz M, Juan Manuel; Garcia Llano, Cesar Fernando

2010-01-01

San Andres Island is the largest emerged portion of the oceanic archipelago of San Andres and Providencia, southwestern Caribbean Sea; it originated as a coralline atoll during Miocene times. The central and highest part of the island consists of a calcareous crest, the San Andres Formation, formed by Neogene lagoonal and reefal deposits. This crest is surrounded by a calcareous platform of Pleistocene age (San Luis Formation) which emerges only along the island coast, whereas its most part is submerged and covered by a Recent reef complex. Fossil material of molluscs from these two formations was collected in various sites throughout the island and taxonomically identified. In the four sites sampled in the San Andres Formation, material belonging to 19 gastropod and 37 bivalve species was obtained, most of them relatively well represented in other geologic formations of the Caribbean region that are stratigraphically situated between the upper Miocene and the middle Pliocene. Some elements occurring in this formation, such as Ostrea haitiensis, Meretrix dariena and Siphocypraea henekeni, were widely distributed in the Caribbean Miocene Province. In the San Luis Formation, material belonging to 18 gastropod and 11 bivalve species was obtained, most of them also represented in the Recent molluscan fauna of the region. The estimated age of this formation is Sangamonian, hence corresponding to similar formations occurring in Grand Cayman, Jamaica, Hispaniola, the Netherlands Antilles and other Caribbean islands, with which it also shows a great similarity in the composition of the molluscan fauna.

Salt tectonics in Santos Basin, Brazil

Energy Technology Data Exchange (ETDEWEB)

Quirk, David G.; Nielsen, Malene; Raven, Madeleine [Maersk Oil and Gas, Copenhagen (Denmark); Menezes, Paulo [Maersk Oil and Gas, Rio de Janeiro, RJ (Brazil)

2008-07-01

From Albian to end Cretaceous times, the inboard part of the Santos Basin in Brazil was affected by extension as salt flowed basinwards under the effect of gravity. Salt rollers, flip-flop salt diapirs and the famous Albian Gap were all formed by this process. Outboard of these extensional structures, contraction was taken up in a wide zone of thickened salt where salt collected. The overburden was carried on top of the salt as it flowed down-dip, with up to 40 km of translation recorded in Albian strata. (author)

[Rets. rmt. : Glucksmann, Andre. Ouest contre Ouest. Pariis, 2003] / Malle Talvet

Index Scriptorium Estoniae

Talvet, Malle

2004-01-01

Prantsuse filosoofi Andre Glucksmanni raamat "Ouest contre Ouest" ehk "Lääs Lääne vastu" käsitleb rahvusvahelisi sündmusi 2002/2003, eelkõige Iraaki, terrorismi, Ameerika Ühendriike ja Prantsusmaad

SU-E-T-401: Feasibility Study of Using ABC to Gate Lung SBRT Treatment

International Nuclear Information System (INIS)

Cao, D; Xie, X; Shepard, D

2014-01-01

Purpose: The current SBRT treatment techniques include free breathing (FB) SBRT and gated FB SBRT. Gated FB SBRT has smaller target and less lung toxicity with longer treatment time. The recent development of direct connectivity between the ABC and linac allowing for automated beam gating. In this study, we have examined the feasibility of using ABC system to gate the lung SBRT treatment. Methods: A CIRS lung phantom with a 3cm sphere-insert and a moving chest plate was used in this study. Sinusoidal motion was used for the FB pattern. An ABC signal was imported to simulate breath holds. 4D-CT was taken in FB mode and average-intensity-projection (AIP) was used to create FB and 50% gated FB SBRT planning CT. A manually gated 3D CT scan was acquired for ABC gated SBRT planning.An SBRT plan was created for each treatment option. A surface-mapping system was used for 50% gating and ABC system was used for ABC gating. A manually gated CBCT scan was also performed to verify setup. Results: Among three options, the ABC gated plan has the smallest PTV of 35.94cc, which is 35% smaller comparing to that of the FB plan. Consequently, the V20 of the left lung reduced by 15% and 23% comparing to the 50% gated FB and FB plans, respectively. The FB plan took 4.7 minutes to deliver, while the 50% gated FB plan took 18.5 minutes. The ABC gated plan delivery took only 10.6 minutes. A stationary target with 3cm diameter was also obtained from the manually gated CBCT scan. Conclusion: A strategy for ABC gated lung SBRT was developed. ABC gating can significantly reduce the lung toxicity while maintaining the target coverage. Comparing to the 50% gated FB SBRT, ABC gated treatment can also provide less lung toxicity as well as improved delivery efficiency. This research is funded by Elekta

Creating an iPhone Application for Collecting Continuous ABC Data

Science.gov (United States)

Whiting, Seth W.; Dixon, Mark R.

2012-01-01

This paper provides an overview and task analysis for creating a continuous ABC data- collection application using Xcode on a Mac computer. Behavior analysts can program an ABC data collection system, complete with a customized list of target clients, antecedents, behaviors, and consequences to be recorded, and have the data automatically sent to…

Põlvas tuli esitusele Andre Laine 29 tantsu / Mati Määrits

Index Scriptorium Estoniae

Määrits, Mati, 1958-

2008-01-01

Põlva Kultuuri- ja Huvikeskuses sai näha Põlvamaa Koolitantsu maakondlikku eelvooru. 52st tantsust 29 tantsu autor on Andre Laine. Kommenteerib ka Tartu Ülikooli Viljandi Kultuuriakadeemia lavakunstide osakonna tantsukunsti õppejõud Kai Valtna

Sobre "La tortuga" de Andrés Holguin

Directory of Open Access Journals (Sweden)

José Puben

1961-04-01

Full Text Available Andrés Holguín no es el primero y, ciertamente, no será el último escritor contemporáneo que, interesado por el problema de los animales que han logrado dimensión fantástica, se proponga, con interés intelectual, analizar e investigar la dimensión e importancia de un animal en la historia de la cultura.

El Santo Niño de Atocha: patrimonio y turismo religioso

Directory of Open Access Journals (Sweden)

Anna M. Fernández Poncela

2010-04-01

Full Text Available this work is a reflection about crossing of roads between cultural patrimony and religious tourism, with the study of case of Santo Niño de Atocha, Plateros, Fresnillo, Zacatecas, Mexico.

Eestlane juhib Ukrainas EBRD investeeringuid / Andre Küüsvek ; interv. Henrik Ilves

Index Scriptorium Estoniae

Küüsvek, Andre

2008-01-01

Seni Euroopa Rekonstruktsiooni- ja Arengupanga (EBRD) Kasahstani osakonda juhtinud Andre Küüsvek valiti juhtima EBRD investeeringuid Ukrainas. Tänavu on plaanis investeerida Ukrainas 1,5 mld. dollarit

[Treatment of lumbar intervertebral disc displacement with chondroitinase ABC--experimental basis for clinical application].

Science.gov (United States)

Takahashi, Toyomi

2004-07-01

After single intradiscal injection of C-ABC in rabbit inter-vertebral discs, water content in the matrix of nucleus pulposus diminished clearly. After similar injection of C-ABC in sheep discs, disc inner pressure was diminished. After single intradiscal injection of C-ABC in dog inter-vertebral discs suffering disc herniation, the syndromes coming from the herniation diminished or disappeared. Based on these observations C-ABC is expected to be a chemonucleolytic agent and a human clinical trial is now in progress.

The ABC gene family in arthropods: comparative genomics and role in insecticide transport and resistance.

Science.gov (United States)

Dermauw, Wannes; Van Leeuwen, Thomas

2014-02-01

About a 100 years ago, the Drosophila white mutant marked the birth of Drosophila genetics. The white gene turned out to encode the first well studied ABC transporter in arthropods. The ABC gene family is now recognized as one of the largest transporter families in all kingdoms of life. The majority of ABC proteins function as primary-active transporters that bind and hydrolyze ATP while transporting a large diversity of substrates across lipid membranes. Although extremely well studied in vertebrates for their role in drug resistance, less is known about the role of this family in the transport of endogenous and exogenous substances in arthropods. The ABC families of five insect species, a crustacean and a chelicerate have been annotated in some detail. We conducted a thorough phylogenetic analysis of the seven arthropod and human ABC protein subfamilies, to infer orthologous relationships that might suggest conserved function. Most orthologous relationships were found in the ABCB half transporter, ABCD, ABCE and ABCF subfamilies, but specific expansions within species and lineages are frequently observed and discussed. We next surveyed the role of ABC transporters in the transport of xenobiotics/plant allelochemicals and their involvement in insecticide resistance. The involvement of ABC transporters in xenobiotic resistance in arthropods is historically not well documented, but an increasing number of studies using unbiased differential gene expression analysis now points to their importance. We give an overview of methods that can be used to link ABC transporters to resistance. ABC proteins have also recently been implicated in the mode of action and resistance to Bt toxins in Lepidoptera. Given the enormous interest in Bt toxicology in transgenic crops, such findings will provide an impetus to further reveal the role of ABC transporters in arthropods. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

Anger and the ABC model underlying Rational-Emotive Behavior Therapy.

Science.gov (United States)

Ziegler, Daniel J; Smith, Phillip N

2004-06-01

The ABC model underlying Ellis's Rational-Emotive Behavior Therapy predicts that people who think more irrationally should display greater trait anger than do people who think less irrationally. This study tested this prediction regarding the ABC model. 186 college students were administered the Survey of Personal Beliefs and the State-Trait Anger Expression Inventory-Second Edition to measure irrational thinking and trait anger, respectively. Students who scored higher on Overall Irrational Thinking and Low Frustration Tolerance scored significantly higher on Trait Anger than did those who scored lower on Overall Irrational Thinking and Low Frustration Tolerance. This indicates support for the ABC model, especially Ellis's construct of irrational beliefs which is central to the model.

Origins of the Salado, Seven Rivers, and San Andres salt margins in Texas and New Mexico: Revision 1: Topical report

International Nuclear Information System (INIS)

Boyd, S.D.; Murphy, P.J.

1987-02-01

The present boundaries of the San Andres, Seven Rivers, and Salado salts generally lie along the periphery of the Palo Duro and Tucumcari Basins. Various geologic mechanisms occurring singularly or in combination determined the positions of the salt margins. These mechanisms include nondeposition of salt and syndepositional and postdepositional dissolution. In New Mexico, San Andres units pinch out against the Pedernal and Sierra Grande Uplifts, indicating that nondeposition established the original salt margins there. Syndepositional dissolution of exposed Upper San Andres salts occurred in response to Guadalupian upwarp of the basin margins. Triassic erosion differentially removed Permian salt-bearing formations along the uplifts. Late Tertiary dissolution is indicated by fill of north-south trending collapse valleys. In Texas, Guadalupian upwarp along the Amarillo Uplift caused pinchout of Units 2 and 3 in the Lower San Andres and influenced the deposition of subsequent salt-bearing strata. The discontinuity of Upper San Andres evaporites across the Amarillo Uplift suggests syndepositional dissolution. Along the eastern and northeastern basin margin, dissolution may have accompanied Triassic erosion of locally uplifted Upper Permian strata. Tertiary dissolution is recognized beneath anomalously thick Ogallala Formation sections that overlie collasped Permian strata. 49 refs., 31 figs., 2 tabs

Giving Voice: Narrating silence, history and memory in André Brink ...

African Journals Online (AJOL)

Giving Voice: Narrating silence, history and memory in André Brink\\'s The Other Side of Silence and Before I Forget. ... Both narrators, though, draw attention to the problems associated with this reconstructive and potentially ... Article Metrics.

Genome-wide identification of whole ATP-binding cassette (ABC) transporters in the intertidal copepod Tigriopus japonicus.

Science.gov (United States)

Jeong, Chang-Bum; Kim, Bo-Mi; Lee, Jae-Seong; Rhee, Jae-Sung

2014-08-05

The ATP-binding cassette (ABC) transporter superfamily is one of the largest transporter gene families and is observed in all animal taxa. Although a large set of transcriptomic data was recently assembled for several species of crustaceans, identification and annotation of the large ABC transporter gene family have been very challenging. In the intertidal copepod Tigriopus japonicus, 46 putative ABC transporters were identified using in silico analysis, and their full-length cDNA sequences were characterized. Phylogenetic analysis revealed that the 46 T. japonicus ABC transporters are classified into eight subfamilies (A-H) that include all the members of all ABC subfamilies, consisting of five ABCA, five ABCB, 17 ABCC, three ABCD, one ABCE, three ABCF, seven ABCG, and five ABCH subfamilies. Of them, unique isotypic expansion of two clades of ABCC1 proteins was observed. Real-time RT-PCR-based heatmap analysis revealed that most T. japonicus ABC genes showed temporal transcriptional expression during copepod development. The overall transcriptional profile demonstrated that half of all T. japonicus ABC genes were strongly associated with at least one developmental stage. Of them, transcripts TJ-ABCH_88708 and TJ-ABCE1 were highly expressed during all developmental stages. The whole set of T. japonicus ABC genes and their phylogenetic relationships will provide a better understanding of the comparative evolution of essential gene family resources in arthropods, including the crustacean copepods.

ABC+SCM=Sant?

OpenAIRE

Dahl, Jonas; Porelius, Jesper

2006-01-01

Background: Companies of today commonly search to gain competitive advantages throughout different forms of co-operation, one of which is referred to as Supply Chain Management. Although little research has been assigned to the topic of how to manage and control this type of relation, lately a growing number of academics has been arguing that ABC is an appropriate mean of controlling this type of relationships. Purpose: The purpose of this thesis is to investigate to what degree the ongoing d...

Phylodynamic Inference with Kernel ABC and Its Application to HIV Epidemiology.

Science.gov (United States)

Poon, Art F Y

2015-09-01

The shapes of phylogenetic trees relating virus populations are determined by the adaptation of viruses within each host, and by the transmission of viruses among hosts. Phylodynamic inference attempts to reverse this flow of information, estimating parameters of these processes from the shape of a virus phylogeny reconstructed from a sample of genetic sequences from the epidemic. A key challenge to phylodynamic inference is quantifying the similarity between two trees in an efficient and comprehensive way. In this study, I demonstrate that a new distance measure, based on a subset tree kernel function from computational linguistics, confers a significant improvement over previous measures of tree shape for classifying trees generated under different epidemiological scenarios. Next, I incorporate this kernel-based distance measure into an approximate Bayesian computation (ABC) framework for phylodynamic inference. ABC bypasses the need for an analytical solution of model likelihood, as it only requires the ability to simulate data from the model. I validate this "kernel-ABC" method for phylodynamic inference by estimating parameters from data simulated under a simple epidemiological model. Results indicate that kernel-ABC attained greater accuracy for parameters associated with virus transmission than leading software on the same data sets. Finally, I apply the kernel-ABC framework to study a recent outbreak of a recombinant HIV subtype in China. Kernel-ABC provides a versatile framework for phylodynamic inference because it can fit a broader range of models than methods that rely on the computation of exact likelihoods. © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

Analysis of the influence of the Colatina Belt in the Campos and Espirito Santo Basins-Brazil; Analise da influencia da Faixa Colatina nas Bacias de Campos e Espirito Santo

Energy Technology Data Exchange (ETDEWEB)

Silva, Gustavo Henrique Teixeira da; Simoes, Luiz Sergio Amarante; Souza, Iata Anderson de [Universidade Estadual Paulista (UNESP), Rio Claro, SP (Brazil). Inst. de Geociencias e Ciencias Exatas

2008-07-01

Recent discoveries in the Espirito Santo Basin confirm the importance of it in the national exploratory scenery (oil and gas production). The new fields like Carapo and Camarupim, beyond others, next to already known Golfinho and Canapu, totalize an addition of 560 million barrels. In this way, studies in the area add importance, as the case of the present research, where if it looked to analyze the influence of Colatina Belt in Espirito Santo Basin and secondarily in Campos Basin. The results had been gotten through the integration of diverse data, such as lineaments extracted from images SRTM, potential maps and analyze of seismic lines. It was concluded that the Colatina Belt if projects for the interior of the basins, but that the same one seems to be dislocated in relation to the direct projection of the continental features, being that its influence can be felt with bigger emphasis in the Campos Basin, while in the Espirito Santo it look like to have low importance with regard to the exploration aspects. Also it was verified the presence of numerous halo kinetic structures that affect all the mapped horizons, this element determine great importance in the generation of structural traps. (author)

A 6-Nucleotide Regulatory Motif within the AbcR Small RNAs of Brucella abortus Mediates Host-Pathogen Interactions.

Science.gov (United States)

Sheehan, Lauren M; Caswell, Clayton C

2017-06-06

In Brucella abortus , two small RNAs (sRNAs), AbcR1 and AbcR2, are responsible for regulating transcripts encoding ABC-type transport systems. AbcR1 and AbcR2 are required for Brucella virulence, as a double chromosomal deletion of both sRNAs results in attenuation in mice. Although these sRNAs are responsible for targeting transcripts for degradation, the mechanism utilized by the AbcR sRNAs to regulate mRNA in Brucella has not been described. Here, two motifs (M1 and M2) were identified in AbcR1 and AbcR2, and complementary motif sequences were defined in AbcR-regulated transcripts. Site-directed mutagenesis of M1 or M2 or of both M1 and M2 in the sRNAs revealed transcripts to be targeted by one or both motifs. Electrophoretic mobility shift assays revealed direct, concentration-dependent binding of both AbcR sRNAs to a target mRNA sequence. These experiments genetically and biochemically characterized two indispensable motifs within the AbcR sRNAs that bind to and regulate transcripts. Additionally, cellular and animal models of infection demonstrated that only M2 in the AbcR sRNAs is required for Brucella virulence. Furthermore, one of the M2-regulated targets, BAB2_0612, was found to be critical for the virulence of B. abortus in a mouse model of infection. Although these sRNAs are highly conserved among Alphaproteobacteria , the present report displays how gene regulation mediated by the AbcR sRNAs has diverged to meet the intricate regulatory requirements of each particular organism and its unique biological niche. IMPORTANCE Small RNAs (sRNAs) are important components of bacterial regulation, allowing organisms to quickly adapt to changes in their environments. The AbcR sRNAs are highly conserved throughout the Alphaproteobacteria and negatively regulate myriad transcripts, many encoding ABC-type transport systems. In Brucella abortus , AbcR1 and AbcR2 are functionally redundant, as only a double abcR1 abcR2 ( abcR1 / 2 ) deletion results in attenuation in

Energy Coupling Factor-Type ABC Transporters for Vitamin Uptake in Prokaryotes

NARCIS (Netherlands)

Erkens, Guus B.; Dosz-Majsnerowska, Maria; ter Beek, Josy; Slotboom, Dirk Jan

2012-01-01

Energy coupling factor (ECF) transporters are a subgroup of ATP-binding cassette (ABC) transporters involved in the uptake of vitamins and micronutrients in prokaryotes. In contrast to classical ABC importers, ECF transporters do not make use of water-soluble substrate binding proteins or domains

Parts harvendas ootamatult Eesti Energia nõukogu / Andres Eilart

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Eilart, Andres

2011-01-01

Majandus- ja kommunikatsiooniminister Juhan Parts otsustas 1. juulil päevapealt Eesti Energia nõukogu liikme kohalt tagasi kutsuda Aivar Reiviku ning Rein Kuusmiku, kes olid vastu Eesti Energia üle viie miljoni euro suurusele investeeringule Weroli rapsiõlitehase juurde rajatavasse elektri- ja küttejaama. Uuteks nõukogu liikmeteks said Andres Saame ja Toomas Tauts

Sociedad, epistemología y metodología en Boaventura de Sousa Santos

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Helder Alejandro Binimelis-Espinoza

2017-08-01

Full Text Available El objetivo de esta publicación es analizar la obra de Boaventura de Sousa Santos, especialmente su comprensión de las sociedades contemporáneas y los desafíos epistemológicos y metodológicos actuales. Mediante una revisión documental de su obra y aportes críticos de otros autores, se distingue su comprensión crítica y utópica de las sociedades actuales, y la necesidad de renovación de los procesos de construcción de conocimiento. Los aportes de este trabajo son, por una parte, integrar la crítica de Santos a la modernidad con su propuesta utópica, y su relación con las epistemologías del sur, la ecología de saberes y la traducción intercultural. Por otra parte, la identificación de estrategias concretas de generación de saberes desde una perspectiva intercultural. Las conclusiones están orientadas hacia una evaluación crítica de la discusión desarrollada con Santos, y su relevancia en el contexto de las ciencias sociales latinoamericanas.

Saberes da ayahuasca e processos educativos na religião do Santo Daime

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Maria Betânia B. Albuquerque

2012-05-01

Full Text Available Este estudo volta-se para os saberes da ayahuasca, beberagem de origem indígenafeita da combinação de um cipó e as folhas de um arbusto da Amazônia, utilizada em diferentescontextos culturais como é o caso da religião brasileira conhecida como Santo Daime. Parto dopressuposto, afirmado nos próprios hinos da doutrina, de que o daime (ayahuasca é um professore que na religião vivencia-se um processo educativo no qual um conjunto de saberes é circulado eapreendido. Metodologicamente, resulta de uma pesquisa bibliográfica, documental e de campo.Têm como fontes a bibliografia sobre as religiões ayahuasqueiras, os cadernos de hinos do SantoDaime e a realização de entrevistas com daimistas do Brasil e outros países. Teoricamente, inspirasenos estudos de Carlos Rodrigues Brandão acerca da educação como cultura e nos escritos deBoaventura de Sousa Santos, restringindo este texto à noção de “ecologia de saberes” deste autor.Dentre os principais saberes do daime destaco: saberes ecológicos-ambientais, cognitivos, estéticos,medicinais, e para a paz.

Asymmetric switching in a homodimeric ABC transporter: a simulation study.

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Jussi Aittoniemi

2010-04-01

Full Text Available ABC transporters are a large family of membrane proteins involved in a variety of cellular processes, including multidrug and tumor resistance and ion channel regulation. Advances in the structural and functional understanding of ABC transporters have revealed that hydrolysis at the two canonical nucleotide-binding sites (NBSs is co-operative and non-simultaneous. A conserved core architecture of bacterial and eukaryotic ABC exporters has been established, as exemplified by the crystal structure of the homodimeric multidrug exporter Sav1866. Currently, it is unclear how sequential ATP hydrolysis arises in a symmetric homodimeric transporter, since it implies at least transient asymmetry at the NBSs. We show by molecular dynamics simulation that the initially symmetric structure of Sav1866 readily undergoes asymmetric transitions at its NBSs in a pre-hydrolytic nucleotide configuration. MgATP-binding residues and a network of charged residues at the dimer interface are shown to form a sequence of putative molecular switches that allow ATP hydrolysis only at one NBS. We extend our findings to eukaryotic ABC exporters which often consist of two non-identical half-transporters, frequently with degeneracy substitutions at one of their two NBSs. Interestingly, many residues involved in asymmetric conformational switching in Sav1866 are substituted in degenerate eukaryotic NBS. This finding strengthens recent suggestions that the interplay of a consensus and a degenerate NBS in eukaroytic ABC proteins pre-determines the sequence of hydrolysis at the two NBSs.

A Coligação Operária de Santos quebrou a pasmaceira Workers’ Colligation of Santos ceased the apathy

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Dainis Karepovs

2006-01-01

Full Text Available Examina-se o surgimento e a ação da Coligação Operária de Santos nas eleições municipais de 29 de novembro de 1925. A Coligação Operária, que atuou até 1930, foi a primeira organização eleitoral criada pelo Partido Comunista do Brasil (PCB e que encontrou muitas resistências na forte cultura abstencionista que impregnava os trabalhadores brasileiros. Formada com base em sindicatos influenciados pelos comunistas, a Coligação Operária foi um dos passos iniciais ensaiados pelos trabalhadores brasileiros em sua inserção na cena político-partidária brasileira.This text discusses the emerging and the action of the Workers’ Colligation of Santos during municipal elections that took place in November, 29, 1925. The Workers’ Colligation, which acted until 1930, was the first electoral organization created by the Communist Party of Brazil (PCB, in Portuguese which had many difficulties because of the resistant abstentionist culture of Brazilian working class. The Workers’ Colligation, whose foundation was based in labour unions, influenced by communists, was one of the initial steps towards Brazilian workers insertion into the political scene in Brazil.

Step 2: Know Your Diabetes ABCs

Science.gov (United States)

... please turn JavaScript on. Feature: Type 2 Diabetes Step 2: Know Your Diabetes ABCs Past Issues / Fall ... 2 Diabetes" Articles Diabetes Is Serious But Manageable / Step 1: Learn About Diabetes / Step 2: Know Your ...

Petroleum systems and hydrocarbon accumulation models in the Santos Basin, SP, Brazil; Sistemas petroliferos e modelos de acumulacao de hidrocarbonetos na Bacia de Santos

Energy Technology Data Exchange (ETDEWEB)

Chang, Hung Kiang; Assine, Mario Luis; Correa, Fernando Santos; Tinen, Julio Setsuo [Universidade Estadual Paulista (UNESP), Rio Claro, SP (Brazil). Lab. de Estudos de Bacias]. E-mails: chang@rc.unesp.br; assine@rc.unesp.br; fscorrea@rc.unesp.br; jstinen@rc.unesp.br; Vidal, Alexandre Campane; Koike, Luzia [Universidade Estadual de Campinas (UNICAMP), Campinas, SP (Brazil). Centro de Estudos de Petroleo]. E-mails: vidal@ige.unicamp.br; luzia@iqm.unicamp.br

2008-07-01

The Santos Basin was formed by rifting process during Mesozoic Afro-American separation. Sediment accumulation initiated with fluvial-lacustrine deposits, passing to evaporitic stage until reaching marginal basin stages. The analysis of hydrocarbon potential of Santos Basin identified two petroleum systems: Guaratiba-Guaruja and Itajai-Acu-Ilhabela. The Guaratiba Formation is less known in the Santos Basin because of small number of wells that have penetrated the rift section. By comparison with Campos Basin, hydrocarbons are of saline lacustrine origin deposited in Aptian age. Analogous to Campos Basin the major source rock is of saline-lacustrine origin, which has been confirmed from geochemical analyses of oil samples recovered from the various fields. These analyses also identified marine source rock contribution, indicating the Itajai-Acu source rock went through oil-window, particularly in structural lows generated by halokynesis. Models of hydrocarbon accumulation consider Guaratiba Formacao as the major source rock for shallow carbonate reservoirs of Guaruja Formacao and for late Albian to Miocene turbidites, as well as siliciclastic and carbonate reservoirs of the rift phase. Migration occurs along salt window and through carrier-beds. The seal rock is composed of shales and limestones intercalated with reservoir facies of the post-rift section and by thick evaporites overlying rift section, especially in the deeper water. In the shallow portion, shale inter-tongued with reservoir rocks is the main seal rock. The hydrocarbon generation and expulsion in the central-north portion of the basin is caused by overburden of a thick Senonian section. Traps can be structural (rollovers and turtle), stratigraphic (pinch-outs) and mixed origins (pinch-outs of turbidites against salt domes). (author)

The ABCs of Student Engagement

Science.gov (United States)

Parsons, Seth A.; Nuland, Leila Richey; Parsons, Allison Ward

2014-01-01

Student engagement is an important consideration for teachers and administrators because it is explicitly associated with achievement. What the authors call the ABC's of engagement they outline as: Affective engagement, Behavioral engagement, and Cognitive engagement. They also present "Three Things Every Teacher Needs to Know about…

A Survey of the ATP-Binding Cassette (ABC) Gene Superfamily in the Salmon Louse (Lepeophtheirus salmonis).

Science.gov (United States)

Carmona-Antoñanzas, Greta; Carmichael, Stephen N; Heumann, Jan; Taggart, John B; Gharbi, Karim; Bron, James E; Bekaert, Michaël; Sturm, Armin

2015-01-01

Salmon lice, Lepeophtheirus salmonis (Krøyer, 1837), are fish ectoparasites causing significant economic damage in the mariculture of Atlantic salmon, Salmo salar Linnaeus, 1758. The control of L. salmonis at fish farms relies to a large extent on treatment with anti-parasitic drugs. A problem related to chemical control is the potential for development of resistance, which in L. salmonis is documented for a number of drug classes including organophosphates, pyrethroids and avermectins. The ATP-binding cassette (ABC) gene superfamily is found in all biota and includes a range of drug efflux transporters that can confer drug resistance to cancers and pathogens. Furthermore, some ABC transporters are recognised to be involved in conferral of insecticide resistance. While a number of studies have investigated ABC transporters in L. salmonis, no systematic analysis of the ABC gene family exists for this species. This study presents a genome-wide survey of ABC genes in L. salmonis for which, ABC superfamily members were identified through homology searching of the L. salmonis genome. In addition, ABC proteins were identified in a reference transcriptome of the parasite generated by high-throughput RNA sequencing (RNA-seq) of a multi-stage RNA library. Searches of both genome and transcriptome allowed the identification of a total of 33 genes / transcripts coding for ABC proteins, of which 3 were represented only in the genome and 4 only in the transcriptome. Eighteen sequences were assigned to ABC subfamilies known to contain drug transporters, i.e. subfamilies B (4 sequences), C (11) and G (2). The results suggest that the ABC gene family of L. salmonis possesses fewer members than recorded for other arthropods. The present survey of the L. salmonis ABC gene superfamily will provide the basis for further research into potential roles of ABC transporters in the toxicity of salmon delousing agents and as potential mechanisms of drug resistance.

Väitlus tumma tekstiga : Hans Anton Schults ja Andres Saal / Katre Kikas

Index Scriptorium Estoniae

Kikas, Katre

2006-01-01

Artiklis käsitletakse H. A. Schults'i (1866-1905) 1903. a. Jakob Hurdale saadetud kirjutisi, kus ta polemiseerib oma kaasaegse Andres Saaliga arutledes "vanade eestlaste" moraali, rahvuse ja religiooni teemal

Santo Tomás y los demás

Directory of Open Access Journals (Sweden)

Alfonso Rincón

1988-10-01

Full Text Available La filosofia del medioevo. VIII Coloquio de la Sociedad Colombiana de Filosofia. J.A. Díaz, J.P. Margot, A.L. Gómez, E. Lákatos, A. Cárdenas, G. Soto, D. Herrera, A. Papacchini, J. Zabalza. Biblioteca Colombiana de Filosofía, Universidad de Santo Tomás, Bogotá, 1987, 138 págs.

Functional analysis of the ATP-binding cassette (ABC) transporter gene family of Tribolium castaneum.

Science.gov (United States)

Broehan, Gunnar; Kroeger, Tobias; Lorenzen, Marcé; Merzendorfer, Hans

2013-01-16

The ATP-binding cassette (ABC) transporters belong to a large superfamily of proteins that have important physiological functions in all living organisms. Most are integral membrane proteins that transport a broad spectrum of substrates across lipid membranes. In insects, ABC transporters are of special interest because of their role in insecticide resistance. We have identified 73 ABC transporter genes in the genome of T. castaneum, which group into eight subfamilies (ABCA-H). This coleopteran ABC family is significantly larger than those reported for insects in other taxonomic groups. Phylogenetic analysis revealed that this increase is due to gene expansion within a single clade of subfamily ABCC. We performed an RNA interference (RNAi) screen to study the function of ABC transporters during development. In ten cases, injection of double-stranded RNA (dsRNA) into larvae caused developmental phenotypes, which included growth arrest and localized melanization, eye pigmentation defects, abnormal cuticle formation, egg-laying and egg-hatching defects, and mortality due to abortive molting and desiccation. Some of the ABC transporters we studied in closer detail to examine their role in lipid, ecdysteroid and eye pigment transport. The results from our study provide new insights into the physiological function of ABC transporters in T. castaneum, and may help to establish new target sites for insect control.

Parents' Perspectives on Braille Literacy: Results from the ABC Braille Study

Science.gov (United States)

Kamei-Hannan, Cheryl; Sacks, Sharon Zell

2012-01-01

Introduction: Parents who were the primary caretakers of children in the Alphabetic and Contracted Braille Study (ABC Braille Study) revealed their perspectives about braille literacy. Methods: A 30-item questionnaire was constructed by the ABC Braille research team, and researchers conducted telephone interviews with 31 parents who were the…

ABC model and the management of costs

Directory of Open Access Journals (Sweden)

Pravdić Predrag

2016-01-01

Full Text Available When a company has multiple objectives at the same time, they all must be considered and balanced when making any business decisions. Linking the markets, capital and resources so as to thus ensure the highest yield is, In fact, the search for competitive advantage as a basic condition for survival in a market economy. In highly detailed systems based on the management of costs or ABC (activity based costing systems, the cost of activities often result in erroneous evaluation of aggregate costs of the action. Improvements in information technology and monitoring decrease of technology costs enabled the ABC system to become a feasible system calculating costs in many organizations.

ABC-F Proteins Mediate Antibiotic Resistance through Ribosomal Protection.

Science.gov (United States)

Sharkey, Liam K R; Edwards, Thomas A; O'Neill, Alex J

2016-03-22

Members of the ABC-F subfamily of ATP-binding cassette proteins mediate resistance to a broad array of clinically important antibiotic classes that target the ribosome of Gram-positive pathogens. The mechanism by which these proteins act has been a subject of long-standing controversy, with two competing hypotheses each having gained considerable support: antibiotic efflux versus ribosomal protection. Here, we report on studies employing a combination of bacteriological and biochemical techniques to unravel the mechanism of resistance of these proteins, and provide several lines of evidence that together offer clear support to the ribosomal protection hypothesis. Of particular note, we show that addition of purified ABC-F proteins to anin vitrotranslation assay prompts dose-dependent rescue of translation, and demonstrate that such proteins are capable of displacing antibiotic from the ribosomein vitro To our knowledge, these experiments constitute the first direct evidence that ABC-F proteins mediate antibiotic resistance through ribosomal protection.IMPORTANCEAntimicrobial resistance ranks among the greatest threats currently facing human health. Elucidation of the mechanisms by which microorganisms resist the effect of antibiotics is central to understanding the biology of this phenomenon and has the potential to inform the development of new drugs capable of blocking or circumventing resistance. Members of the ABC-F family, which includelsa(A),msr(A),optr(A), andvga(A), collectively yield resistance to a broader range of clinically significant antibiotic classes than any other family of resistance determinants, although their mechanism of action has been controversial since their discovery 25 years ago. Here we present the first direct evidence that proteins of the ABC-F family act to protect the bacterial ribosome from antibiotic-mediated inhibition. Copyright © 2016 Sharkey et al.

André Leroi-Gourhan (25 août 1911–19 février 1986)

OpenAIRE

Soulier, Philippe

2007-01-01

André Leroi-Gourhan (25th August 1911 – 19th February 1986) A short biography of André Leroi-Gourhan is here presented, beginning in 1927, at the moment of his student years, until his retirement in 1982. It rests on a systematic analysis of his publications and on his personal and professional archives, collected and studied for the first time in 2001 when the author was temporally engaged by the CNRS. Going beyond the pure biography of events, such as those already presented in numerous po...

Postsotsialismist vaatemängulinna = From Post-Socialism to the City of the Spectacle / Andres Kurg

Index Scriptorium Estoniae

Kurg, Andres, 1975-

2007-01-01

Büroo Alver Trummal Arhitektid töödest, Andres Alverist ja Tiit Trummalist. Ärihoonest Tallinnas Rävala pst. 4. Autorid: Andres Alver, Tiit Trummal, Tarmo Laht, Indrek Rünkla, Ulla Mets, Sven Koppel. Konstruktor Eido Uustalu (Eesti Projekt). Projekt 2001, valmis 2006. City Plazast Tallinnas Tartu mnt. 2. Autorid: A. Alver, T. Trummal, T. Laht, I. Rünkla, Martin Melioranski, U. Mets. Konstruktor: Tiit Masso, Pike Projekt. Sisekujundus (fuajeed, restoran): Pille Lausmäe. Projekt 2001, valmis 2004. Lõige, põhiplaan, 3 värv. välis- ja 5 sisevaadet

Genome-wide analysis of ATP-binding cassette (ABC) transporters in the sweetpotato whitefly, Bemisia tabaci.

Science.gov (United States)

Tian, Lixia; Song, Tianxue; He, Rongjun; Zeng, Yang; Xie, Wen; Wu, Qingjun; Wang, Shaoli; Zhou, Xuguo; Zhang, Youjun

2017-04-26

ABC transporter superfamily is one of the largest and ubiquitous groups of proteins. Because of their role in detoxification, insect ABC transporters have gained more attention in recent years. In this study, we annotated ABC transporters from a newly sequenced sweetpotato whitefly genome. Bemisia tabaci Q biotype is an emerging global invasive species that has caused extensive damages to field crops as well as ornamental plants. A total of 55 ABC transporters containing all eight described subfamilies (A to H) were identified in the B. tabaci Q genome, including 8 ABCAs, 3 ABCBs, 6 ABCCs, 2 ABCDs, 1 ABCE, 3 ABCFs, 23 ABCGs and 9 ABCHs. In comparison to other species, subfamilies G and H in both phloem- and blood-sucking arthropods are expanded. The temporal expression profiles of these 55 ABC transporters throughout B. tabaci developmental stages and their responses to imidacloprid, a neonicotinoid insecticide, were investigated using RNA-seq analysis. Furthermore, the mRNA expression of 24 ABC transporters (44% of the total) representing all eight subfamilies was confirmed by the quantitative real-time PCR (RT-qPCR). Furthermore, mRNA expression levels estimated by RT-qPCR and RNA-seq analyses were significantly correlated (r = 0.684, p analysis of the entire repertoire of ABC transporters in B. tabaci. The identification of these ABC transporters, their temporal expression profiles during B. tabaci development, and their response to a neonicotinoid insecticide lay the foundation for functional genomic understanding of their contribution to the invasiveness of B. tabaci.

The ABCs of particle physics

CERN Document Server

Biron, Lauren

2016-01-01

For lovers of rhymes and anthropomorphic Higgs bosons, Symmetry presents its first published board book, The ABCs of Particle Physics. Use it as an illustrated guide to basic particle- and astrophysics terms, or read it to your infant at bedtime, if you don’t mind their first word being “quark.”

The Oldest Case of Decapitation in the New World (Lapa do Santo, East-Central Brazil).

Science.gov (United States)

Strauss, André; Oliveira, Rodrigo Elias; Bernardo, Danilo V; Salazar-García, Domingo C; Talamo, Sahra; Jaouen, Klervia; Hubbe, Mark; Black, Sue; Wilkinson, Caroline; Richards, Michael Phillip; Araujo, Astolfo G M; Kipnis, Renato; Neves, Walter Alves

2015-01-01

We present here evidence for an early Holocene case of decapitation in the New World (Burial 26), found in the rock shelter of Lapa do Santo in 2007. Lapa do Santo is an archaeological site located in the Lagoa Santa karst in east-central Brazil with evidence of human occupation dating as far back as 11.7-12.7 cal kyBP (95.4% interval). An ultra-filtered AMS age determination on a fragment of the sphenoid provided an age range of 9.1-9.4 cal kyBP (95.4% interval) for Burial 26. The interment was composed of an articulated cranium, mandible and first six cervical vertebrae. Cut marks with a v-shaped profile were observed in the mandible and sixth cervical vertebra. The right hand was amputated and laid over the left side of the face with distal phalanges pointing to the chin and the left hand was amputated and laid over the right side of the face with distal phalanges pointing to the forehead. Strontium analysis comparing Burial 26's isotopic signature to other specimens from Lapa do Santo suggests this was a local member of the group. Therefore, we suggest a ritualized decapitation instead of trophy-taking, testifying for the sophistication of mortuary rituals among hunter-gatherers in the Americas during the early Archaic period. In the apparent absence of wealth goods or elaborated architecture, Lapa do Santo's inhabitants seemed to use the human body to express their cosmological principles regarding death.

fbpABC gene cluster in Neisseria meningitidis is transcribed as an operon.

Science.gov (United States)

Khun, H H; Deved, V; Wong, H; Lee, B C

2000-12-01

The neisserial fbpABC locus has been proposed to constitute a single transcriptional unit. To confirm this operonic arrangement, transcription assays using reverse transcriptase PCR amplification were conducted with Neisseria meningitidis. The presence of fbpAB and fbpBC transcripts obtained by priming cDNA synthesis with an fbpC-sequence-specific oligonucleotide indicates that fbpABC is organized as a single expression unit. The ratio of fbpA to fbpABC mRNA was approximately between 10- to 20-fold, as determined by real-time quantitative PCR.

Volume-Dependent Overestimation of Spontaneous Intracerebral Hematoma Volume by the ABC/2 Formula

International Nuclear Information System (INIS)

Chih-Wei Wang; Chun-Jung Juan; Hsian-He Hsu; Hua-Shan Liu; Cheng-Yu Chen; Chun-Jen Hsueh; Hung-Wen Kao; Guo-Shu Huang; Yi-Jui Liu; Chung-Ping Lo

2009-01-01

Background: Although the ABC/2 formula has been widely used to estimate the volume of intracerebral hematoma (ICH), the formula tends to overestimate hematoma volume. The volume-related imprecision of the ABC/2 formula has not been documented quantitatively. Purpose: To investigate the volume-dependent overestimation of the ABC/2 formula by comparing it with computer-assisted volumetric analysis (CAVA). Material and Methods: Forty patients who had suffered spontaneous ICH and who had undergone non-enhanced brain computed tomography scans were enrolled in this study. The ICH volume was estimated based on the ABC/2 formula and also calculated by CAVA. Based on the ICH volume calculated by the CAVA method, the patients were divided into three groups: group 1 consisted of 17 patients with an ICH volume of less than 20 ml; group 2 comprised 13 patients with an ICH volume of 20 to 40 ml; and group 3 was composed of 10 patients with an ICH volume larger than 40 ml. Results: The mean estimated hematoma volume was 43.6 ml when using the ABC/2 formula, compared with 33.8 ml when using the CAVA method. The mean estimated difference was 1.3 ml, 4.4 ml, and 31.4 ml for groups 1, 2, and 3, respectively, corresponding to an estimation error of 9.9%, 16.7%, and 37.1% by the ABC/2 formula (P<0.05). Conclusion: The ABC/2 formula significantly overestimates the volume of ICH. A positive association between the estimation error and the volume of ICH is demonstrated

Applying Activity Based Costing (ABC) Method to Calculate Cost Price in Hospital and Remedy Services.

Science.gov (United States)

Rajabi, A; Dabiri, A

2012-01-01

Activity Based Costing (ABC) is one of the new methods began appearing as a costing methodology in the 1990's. It calculates cost price by determining the usage of resources. In this study, ABC method was used for calculating cost price of remedial services in hospitals. To apply ABC method, Shahid Faghihi Hospital was selected. First, hospital units were divided into three main departments: administrative, diagnostic, and hospitalized. Second, activity centers were defined by the activity analysis method. Third, costs of administrative activity centers were allocated into diagnostic and operational departments based on the cost driver. Finally, with regard to the usage of cost objectives from services of activity centers, the cost price of medical services was calculated. The cost price from ABC method significantly differs from tariff method. In addition, high amount of indirect costs in the hospital indicates that capacities of resources are not used properly. Cost price of remedial services with tariff method is not properly calculated when compared with ABC method. ABC calculates cost price by applying suitable mechanisms but tariff method is based on the fixed price. In addition, ABC represents useful information about the amount and combination of cost price services.

Vulkaner andre steder i Solsystemet

DEFF Research Database (Denmark)

Haack, Henning

2007-01-01

Jupiters måne, Io, og man regner man med at Venus og formentlig også Mars stadig er vulkansk aktive. Ved at rette blikket ud i solsystemet har vi  mulighed for at studere vulkansk aktivitet under helt anderledes betingelser end her på Jorden. Hvad sker der f.eks., hvis tyngdekraften er svagere, eller...... planetens overflade måske er gloende varm? Vulkanerne andre steder i Solsystemet overgår på mange måder dem på Jorden. Venus er den planet i solsystemet, der har flest vulkaner, Mars har de største og højeste vulkaner, asteroiden Vesta har de ældste, og Jupiters måne Io har de mest aktive vulkaner i...

Origen de la surgencia del Balneario de San Andrés (Provincia de Jaén)

OpenAIRE

Hidalgo Estévez, Mari Carmen; Rey Arrans, Javier; Redondo, L.

1997-01-01

The hydrogeological context of the San Andrés spa (province of Jaén) is analysed in this work. Piezometric data, hydrochemical analysis and groundwater quality trends are discussed for groundwater samples obtained from the main aquifer units in the region (jurassic carbonatic aquifer and miocene detrital aquifer) in order to stablish the origin of the San Andrés spring. Considering altitude, discharge rate, temperature and hydrochemical features of the spring, it seems to be related to the mi...

Actual stage of organic geochemical knowledge from Campos and Espirito Santo basins, Brazil

International Nuclear Information System (INIS)

Gaglianone, P.C.; Trindade, L.A.F.

1987-01-01

Campos and Espirito Santo basins display several similar geochemical aspects. The microbial and other degradation processes caused changes in the composition of the oils in the reservoir rocks. The oils are biodegraded in different degrees, with the reservoir temperature developing an important role in the control of the biodegradation process. The migration pathway model is similar for Campos and Espirito Santo basins, involving the upward secondary migration through a window in the evaporitic seals. The oils passed to the marine sequence where migration and accumulation were controlled by faults, regional unconformities and by reservoirs. The geochemical correlation of oils are realized by gaseous and liquid chromatography analysis, carbon isotopes and biolabelled compounds. (author)

Insight into Two ABC Transporter Families Involved in Lantibiotic Resistance

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Rebecca Clemens

2018-01-01

Full Text Available Antimicrobial peptides, which contain (methyl-lanthionine-rings are called lantibiotics. They are produced by several Gram-positive bacteria and are mainly active against these bacteria. Although these are highly potent antimicrobials, some human pathogenic bacteria express specific ABC transporters that confer resistance and counteract their antimicrobial activity. Two distinct ABC transporter families are known to be involved in this process. These are the Cpr- and Bce-type ABC transporter families, named after their involvement in cationic peptide resistance in Clostridium difficile, and bacitracin efflux in Bacillus subtilis, respectively. Both resistance systems differentiate to each other in terms of the proteins involved. Here, we summarize the current knowledge and describe the divergence as well as the common features present in both the systems to confer lantibiotic resistance.

Proceedings of the 3. Summer School Jorge Andre Swieca in Nuclear Physics

International Nuclear Information System (INIS)

Lima, C.L.; Nemes, M.C.; Wolynec, E.

1987-01-01

This book contents the lectures and seminars presented during the Jorge Andre Swieca III Summer School-Nuclear Physics 1987 which happened in February 1987 in Itaipava - Rio de Janeiro - Brazil. (A.C.A.S.) [pt

Preliminary lifetime predictions for 304 stainless steel as the LANL ABC blanket material

International Nuclear Information System (INIS)

Park, J.J.; Buksa, J.J.; Houts, M.G.; Arthur, E.D.

1997-11-01

The prediction of materials lifetime in the preconceptual Los Alamos National Laboratory (LANL) Accelerator-Based Conversion of Plutonium (ABC) is of utmost interest. Because Hastelloy N showed good corrosion resistance to the Oak Ridge National Laboratory Molten Salt Reactor Experiment fuel salt that is similar to the LANL ABC fuel salt, Hastelloy N was originally proposed for the LANL ABC blanket material. In this paper, the possibility of using 304 stainless steel as a replacement for the Hastelloy N is investigated in terms of corrosion issues and fluence-limit considerations. An attempt is made, based on the previous Fast Flux Test Facility design data, to predict the preliminary lifetime estimate of the 304 stainless steel used in the blanket region of the LANL ABC

Andrés Rivera, Escritor social

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Marta Waldegaray

2006-07-01

Full Text Available La narrativa de Andrés Rivera hace de la historia el material de origen de la escritura y de su convicción política de izquierda el molde en el cual desde hace ya más de cuatro décadas su escritura adquiere forma.Acontecimiento histórico, circunstancia política, poseen en sus primeras novelas el valor de verdad política, de testimonio social. La convicción ideológica que sus libros exhiben se acompaña de una trayectoria literaria que, en su práctica inicial, fue confiada a la representación r...

Single liposome analysis of peptide translocation by the ABC transporter TAPL.

Science.gov (United States)

Zollmann, Tina; Moiset, Gemma; Tumulka, Franz; Tampé, Robert; Poolman, Bert; Abele, Rupert

2015-02-17

ATP-binding cassette (ABC) transporters use ATP to drive solute transport across biological membranes. Members of this superfamily have crucial roles in cell physiology, and some of the transporters are linked to severe diseases. However, understanding of the transport mechanism, especially of human ABC exporters, is scarce. We reconstituted the human lysosomal polypeptide ABC transporter TAPL, expressed in Pichia pastoris, into lipid vesicles (liposomes) and performed explicit transport measurements. We analyzed solute transport at the single liposome level by monitoring the coincident fluorescence of solutes and proteoliposomes in the focal volume of a confocal microscope. We determined a turnover number of eight peptides per minute, which is two orders of magnitude higher than previously estimated from macroscopic measurements. Moreover, we show that TAPL translocates peptides against a large concentration gradient. Maximal filling is not limited by an electrochemical gradient but by trans-inhibition. Countertransport and reversibility studies demonstrate that peptide translocation is a strictly unidirectional process. Altogether, these data are included in a refined model of solute transport by ABC exporters.

APLICATION OF ABC METHOD FROM AN OPERATOR OF WATER AND SEWERAGE

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FÜLÖP ÁRPÁD-ZOLTÁN

2016-12-01

Full Text Available At the time of the appearance of the ABC method, many specialists considered that they found the most opportune method of calculation to allocate the overhead costs on the cost objects, otherwise said to be able to calculate the total cost of a product or service. Because the method is based on determining the total cost, we can consider that the ABC method is not a method of costing, but rather a method of cost management. Unfortunately, in the specialized literature of Roumania there are many approaches which consider that the ABC method is a method of costing in the traditional way, although in our opinion it is not. Application of ABC method to a regional operator of water and sewerage shows us the possibilities of the method, the possibilities that are offered in the field of cost and administration overhead management, respectively of the establishment of the accounting result on the different cost objects. In case of the regional operator the calculation object is the city or township in which provides the services of water and sewage.

“O Negro André”: a questão racial na vida e no pensamento do abolicionista André Rebouças

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Anita Maria Pequeno Soares

2017-08-01

Full Text Available The main objective of this work was to analyze how the context of racial relations influenced the construction of the self and the intellectual production of black intellectual and abolitionist André Rebouças. Through primary sources, it was possible to recreate the process of “self construction” lived by André Rebouças as a black man who had African ancestry. It was possible to notice that some characteristics of his social thought became radical at the same time the self-recognition of his racial condition became deeper, during the period in which he was self-exiled from Brazil, immediately after the proclamation of the republic in 1889. During his life in Africa, he broke his silence about his racial reality. In this period, the construction of his self goes through a transformation, as he begins to see himself and to reaffirm himself as a black and African man. This awaken to “racial consciousness” was interpreted, like Mattos suggested (2010, inspired by the concept of “double consciousness”, elaborated by Du Bois and further developed by Paul Gilroy in “The Black Atlantic” (2012.

ABC estimation of unit costs for emergency department services.

Science.gov (United States)

Holmes, R L; Schroeder, R E

1996-04-01

Rapid evolution of the health care industry forces managers to make cost-effective decisions. Typical hospital cost accounting systems do not provide emergency department managers with the information needed, but emergency department settings are so complex and dynamic as to make the more accurate activity-based costing (ABC) system prohibitively expensive. Through judicious use of the available traditional cost accounting information and simple computer spreadsheets. managers may approximate the decision-guiding information that would result from the much more costly and time-consuming implementation of ABC.

Globaliseerumine : oht või võimalus? / Andres Arrak

Index Scriptorium Estoniae

Arrak, Andres, 1958-2017

2007-01-01

Globaliseerumise ja võrgustumise muutumine võimaluseks või ohuks sõltub konkreetse riigi majanduse ja tööturu kohanemisvõimest. Globaalsete finantsvoogude kirjeldus, kapitali ja Eestisse tulevate rahavoogude analüüs ning hinnang Eesti tööturu paindlikkusele ja ettevõtjate innovatiivsusele. Graafikud: Otse- ja portfelliinvesteeringute ning laenude sissevool Eestisse 1992-2006; Diagramm: Eesti tööjõuturg sammub Ameerika jälgedes. Vt. samas: Andres Saarniit. Raha ei ole kuhugi kadunud

Metodologia ABC: implantação numa microempresa ABC methodology: implementation on a micro firm

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Orlando Duran

2000-08-01

Full Text Available Este trabalho relata a implantação da metodologia de custos baseados em atividades numa microempresa do ramo metalúrgico. A proposta pretende demonstrar a viabilidade de aplicar esta técnica em empresas sem importar seu tamanho, só realizando algumas adaptações que garantam baixo investimento e curto espaço de tempo para obter os resultados. Na parte final do trabalho se realiza uma análise dos resultados obtidos verificando-se o potencial da informação gerada pela metodologia e seu uso como ferramenta de gestão.This paper presents an implementation of the activity based costing (ABC methodology in a small firm. The approach presented is intended to demonstrate the feasibility of applying the ABC methodology at any sized firm, only through few adaptations for ensuring low investments fees and speed in obtaining results and information from the system. Discussion about the results obtained during the implementation case are presented and the potential of using the information generated from the system as a managing tool is commented.

Intestinal parasites in a quilombola community of the Northern State of Espírito Santo, Brazil Parasitos intestinais em comunidade quilombola do Norte do Espírito Santo, Brasil

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Schayra Minine Damazio

2013-06-01

Full Text Available The aim of this study was to determine the occurrence of intestinal parasites in a quilombola community from the northern Espírito Santo, Brazil. Descendants of slaves who arrived in Brazil in the sixteenth century, this population settled in the municipality of São Mateus in 1858. Fresh fecal samples from 82 individuals who agreed to participate in the study were collected between August 2009 and July 2010, and immediately sent to the Clinical Laboratory of the Centro Universitário Norte do Espírito Santo of the Universidade Federal do Espírito Santo for analysis. Out of all the participants, 36 (43.9% were male and 46 (56.1% were female, whose ages ranged from six to 85 years. The study of the occurrence of intestinal parasites indicated that 35 individuals (42.7% were infected with at least one intestinal parasite. Among helminths, the most frequent were hookworms, with a rate of 14.6%. With regard to protozoa, Entamoeba coli, Entamoeba histolytica/Entamoeba dispar and Endolimax nana stood out, with frequencies of 23.2%, 8.5% and 4.9%, respectively. The occurrence of biparasitism was observed in 13 of the 82 subjects, accounting for 15.8%, and no cases of multiple parasitic infections were observed. It was concluded that the reduction of cases of intestinal diseases due to parasites will only be achieved with the improvement of basic sanitation and quality of life of quilombola populations.O objetivo do presente estudo foi determinar a ocorrência de parasitos intestinais em população quilombola do Norte do Espírito Santo. Descendentes de escravos que chegaram ao Brasil a partir do século XVI, essa população estabeleceu-se no município de São Mateus no ano de 1858. Entre agosto de 2009 e julho de 2010, amostras fecais de 82 indivíduos que aceitaram participar do trabalho foram coletadas, a fresco, e, imediatamente, encaminhadas ao Laboratório de Análises Clínicas do Centro Universitário Norte do Espírito Santo da

The ABCs of Activity-Based Costing: A Cost Containment and Reallocation Tool.

Science.gov (United States)

Turk, Frederick J.

1992-01-01

This article describes activity-based costing (ABC) and how this tool may help management understand the costs of major activities and identify possible alternatives. Also discussed are the traditional costing systems used by higher education and ways of applying ABC to higher education. (GLR)

Identification of ABC transporters acting in vitamin B12 metabolism in Caenorhabditis elegans.

Science.gov (United States)

McDonald, Megan K; Fritz, Julie-Anne; Jia, Dongxin; Scheuchner, Deborah; Snyder, Floyd F; Stanislaus, Avalyn; Curle, Jared; Li, Liang; Stabler, Sally P; Allen, Robert H; Mains, Paul E; Gravel, Roy A

2017-12-01

Vitamin B 12 (cobalamin, Cbl) is a micronutrient essential to human health. Cbl is not utilized as is but must go through complex subcellular and metabolic processing to generate two cofactor forms: methyl-Cbl for methionine synthase, a cytosolic enzyme; and adenosyl-Cbl for methylmalonyl-CoA mutase, a mitochondrial enzyme. Some 10-12 human genes have been identified responsible for the intracellular conversion of Cbl to cofactor forms, including genes that code for ATP-binding cassette (ABC) transporters acting at the lysosomal and plasma membranes. However, the gene for mitochondrial uptake is not known. We hypothesized that ABC transporters should be candidates for other uptake and efflux functions, including mitochondrial transport, and set out to screen ABC transporter mutants for blocks in Cbl utilization using the nematode roundworm Caenorhabditis elegans. Thirty-seven mutant ABC transporters were screened for the excretion of methylmalonic acid (MMA), which should result from loss of Cbl transport into the mitochondria. One mutant, wht-6, showed elevated MMA excretion and reduced [ 14 C]-propionate incorporation, pointing to a functional block in methylmalonyl-CoA mutase. In contrast, the wht-6 mutant appeared to have a normal cytosolic pathway based on analysis of cystathionine excretion, suggesting that cytosolic methionine synthase was functioning properly. Further, the MMA excretion in wht-6 could be partially reversed by including vitamin B 12 in the assay medium. The human ortholog of wht-6 is a member of the G family of ABC transporters. We propose wht-6 as a candidate for the transport of Cbl into mitochondria and suggest that a member of the corresponding ABCG family of ABC transporters has this role in humans. Our ABC transporter screen also revealed that mrp-1 and mrp-2 mutants excreted lower MMA than wild type, suggesting they were concentrating intracellular Cbl, consistent with the cellular efflux defect proposed for the mammalian MRP1 ABC

Regional inequalities in Espirito Santo: perspective of petroleum exploration; Desigualdades regionais no Espirito Santo: perspectivas da fronteira de exploracao petrolifera

Energy Technology Data Exchange (ETDEWEB)

Rodrigues, Viviane Mozine [Centro Universitario Vila Velha (UVV), ES (Brazil)

2008-07-01

Do donate the subject of the present article look to know the possible impacts about the space distribution of the wealth before the tendencies of exploration of petroleum and natural gas in the Espirito Santo it goes: will it be the exploration activity and production of petroleum and natural gas an element of increase of problems of the regional inequalities? The central object is to examines the the distribution of petroleum royalties among the state region, enforcing or finishing it. (author)

Analysis of ABC (D) stratification for screening patients with gastric cancer.

Science.gov (United States)

Kudo, Tomohiro; Kakizaki, Satoru; Sohara, Naondo; Onozato, Yasuhiro; Okamura, Shinichi; Inui, Yoshikatsu; Mori, Masatomo

2011-11-21

To evaluate the value of ABC (D) stratification [combination of serum pepsinogen and Helicobacter pylori (H. pylori) antibody] of patients with gastric cancer. Ninety-five consecutive patients with gastric cancer were enrolled into the study. The serum pepsinogen I (PG I)/pepsinogen II (PG II) and H. pylori antibody levels were measured. Patients were classified into five groups of ABC (D) stratification according to their serological status. Endoscopic findings of atrophic gastritis and histological differentiation were also analyzed in relation to the ABC (D) stratification. The mean patient age was (67.9 ± 8.9) years. Three patients (3.2%) were classified into group A, 7 patients (7.4%) into group A', 27 patients (28.4%) into group B, 54 patients (56.8%) into group C, and 4 patients (4.2%) into group D, respectively. There were only three cases in group A when the patients taking acid proton pump inhibitors and those who had undergone eradication therapy for H. pylori (group A') were excluded. These three cases had mucosal atrophy in the grey zone according to the diagnostic manual of ABC (D) stratification. Histologically, the mean age of the patients with well differentiated adenocarcinoma was significantly higher than that of the patients with poorly differentiated adenocarcinoma (P ABC (D) stratification is a good method for screening patients with gastric cancers. Endoscopy is needed for grey zone cases to check the extent of mucosal atrophy.

Phylogenetic analysis of fungal ABC transporters

NARCIS (Netherlands)

Kovalchuk, A.; Driessen, A.J.M.

2010-01-01

Background: The superfamily of ABC proteins is among the largest known in nature. Its members are mainly, but not exclusively, involved in the transport of a broad range of substrates across biological membranes. Many contribute to multidrug resistance in microbial pathogens and cancer cells. The

75 FR 49549 - ABC & D Recycling, Inc.-Lease and Operation Exemption-a Line of Railroad in Ware, MA

Science.gov (United States)

2010-08-13

... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35397] ABC & D Recycling, Inc.--Lease and Operation Exemption--a Line of Railroad in Ware, MA ABC & D Recycling, Inc. (ABC & D..., ABC & D Recycling, Inc.--Lease and Operation Exemption--a Line of Railroad in Ware, Massachusetts (STB...

Strategic analysis of ABC Systems and its potential future product

OpenAIRE

Lam, Nancy M.

2006-01-01

ABC Systems Limited is a provider of data communication software. Its main product line is protocol conversion software. ABC has developed several other products including some hardware products, but the main success remains the protocol conversion software developed over 10 years ago. The company is having difficulties discovering and developing a profitable and achievable new product and target market. The need for the protocol conversion software is diminishing as the standard of TCP/IP is...

The Oldest Case of Decapitation in the New World (Lapa do Santo, East-Central Brazil.

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André Strauss

Full Text Available We present here evidence for an early Holocene case of decapitation in the New World (Burial 26, found in the rock shelter of Lapa do Santo in 2007. Lapa do Santo is an archaeological site located in the Lagoa Santa karst in east-central Brazil with evidence of human occupation dating as far back as 11.7-12.7 cal kyBP (95.4% interval. An ultra-filtered AMS age determination on a fragment of the sphenoid provided an age range of 9.1-9.4 cal kyBP (95.4% interval for Burial 26. The interment was composed of an articulated cranium, mandible and first six cervical vertebrae. Cut marks with a v-shaped profile were observed in the mandible and sixth cervical vertebra. The right hand was amputated and laid over the left side of the face with distal phalanges pointing to the chin and the left hand was amputated and laid over the right side of the face with distal phalanges pointing to the forehead. Strontium analysis comparing Burial 26's isotopic signature to other specimens from Lapa do Santo suggests this was a local member of the group. Therefore, we suggest a ritualized decapitation instead of trophy-taking, testifying for the sophistication of mortuary rituals among hunter-gatherers in the Americas during the early Archaic period. In the apparent absence of wealth goods or elaborated architecture, Lapa do Santo's inhabitants seemed to use the human body to express their cosmological principles regarding death.

Calculating the tumor volume of acoustic neuromas: comparison of ABC/2 formula with planimetry method.

Science.gov (United States)

Yu, Yi-Lin; Lee, Meei-Shyuan; Juan, Chun-Jung; Hueng, Dueng-Yuan

2013-08-01

The ABC/2 equation is commonly applied to measure the volume of intracranial hematoma. However, the precision of ABC/2 equation in estimating the tumor volume of acoustic neuromas is less addressed. The study is to evaluate the accuracy of the ABC/2 formula by comparing with planimetry method for estimating the tumor volumes. Thirty-two patients diagnosed with acoustic neuroma received contrast-enhanced magnetic resonance imaging of brain were recruited. The volume was calculated by the ABC/2 equation and planimetry method (defined as exact volume) at the same time. The 32 patients were divided into three groups by tumor volume to avoid volume-dependent overestimation (6 ml). The tumor volume by ABC/2 method was highly correlated to that calculated by planimetry method using linear regression analysis (R2=0.985). Pearson correlation coefficient (r=0.993, pABC/2 formula is an easy method in estimating the tumor volume of acoustic neuromas that is not inferior to planimetry method. Copyright © 2013 Elsevier B.V. All rights reserved.

Genome-Wide Identification, Characterization and Phylogenetic Analysis of ATP-Binding Cassette (ABC) Transporter Genes in Common Carp (Cyprinus carpio).

Science.gov (United States)

Liu, Xiang; Li, Shangqi; Peng, Wenzhu; Feng, Shuaisheng; Feng, Jianxin; Mahboob, Shahid; Al-Ghanim, Khalid A; Xu, Peng

2016-01-01

The ATP-binding cassette (ABC) gene family is considered to be one of the largest gene families in all forms of prokaryotic and eukaryotic life. Although the ABC transporter genes have been annotated in some species, detailed information about the ABC superfamily and the evolutionary characterization of ABC genes in common carp (Cyprinus carpio) are still unclear. In this research, we identified 61 ABC transporter genes in the common carp genome. Phylogenetic analysis revealed that they could be classified into seven subfamilies, namely 11 ABCAs, six ABCBs, 19 ABCCs, eight ABCDs, two ABCEs, four ABCFs, and 11 ABCGs. Comparative analysis of the ABC genes in seven vertebrate species including common carp, showed that at least 10 common carp genes were retained from the third round of whole genome duplication, while 12 duplicated ABC genes may have come from the fourth round of whole genome duplication. Gene losses were also observed for 14 ABC genes. Expression profiles of the 61 ABC genes in six common carp tissues (brain, heart, spleen, kidney, intestine, and gill) revealed extensive functional divergence among the ABC genes. Different copies of some genes had tissue-specific expression patterns, which may indicate some gene function specialization. This study provides essential genomic resources for future studies in common carp.

Genome-Wide Identification, Characterization and Phylogenetic Analysis of ATP-Binding Cassette (ABC) Transporter Genes in Common Carp (Cyprinus carpio)

Science.gov (United States)

Peng, Wenzhu; Feng, Shuaisheng; Feng, Jianxin; Mahboob, Shahid; Al-Ghanim, Khalid A.

2016-01-01

The ATP-binding cassette (ABC) gene family is considered to be one of the largest gene families in all forms of prokaryotic and eukaryotic life. Although the ABC transporter genes have been annotated in some species, detailed information about the ABC superfamily and the evolutionary characterization of ABC genes in common carp (Cyprinus carpio) are still unclear. In this research, we identified 61 ABC transporter genes in the common carp genome. Phylogenetic analysis revealed that they could be classified into seven subfamilies, namely 11 ABCAs, six ABCBs, 19 ABCCs, eight ABCDs, two ABCEs, four ABCFs, and 11 ABCGs. Comparative analysis of the ABC genes in seven vertebrate species including common carp, showed that at least 10 common carp genes were retained from the third round of whole genome duplication, while 12 duplicated ABC genes may have come from the fourth round of whole genome duplication. Gene losses were also observed for 14 ABC genes. Expression profiles of the 61 ABC genes in six common carp tissues (brain, heart, spleen, kidney, intestine, and gill) revealed extensive functional divergence among the ABC genes. Different copies of some genes had tissue-specific expression patterns, which may indicate some gene function specialization. This study provides essential genomic resources for future studies in common carp. PMID:27058731

Genome-Wide Identification, Characterization and Phylogenetic Analysis of ATP-Binding Cassette (ABC Transporter Genes in Common Carp (Cyprinus carpio.

Directory of Open Access Journals (Sweden)

Xiang Liu

Full Text Available The ATP-binding cassette (ABC gene family is considered to be one of the largest gene families in all forms of prokaryotic and eukaryotic life. Although the ABC transporter genes have been annotated in some species, detailed information about the ABC superfamily and the evolutionary characterization of ABC genes in common carp (Cyprinus carpio are still unclear. In this research, we identified 61 ABC transporter genes in the common carp genome. Phylogenetic analysis revealed that they could be classified into seven subfamilies, namely 11 ABCAs, six ABCBs, 19 ABCCs, eight ABCDs, two ABCEs, four ABCFs, and 11 ABCGs. Comparative analysis of the ABC genes in seven vertebrate species including common carp, showed that at least 10 common carp genes were retained from the third round of whole genome duplication, while 12 duplicated ABC genes may have come from the fourth round of whole genome duplication. Gene losses were also observed for 14 ABC genes. Expression profiles of the 61 ABC genes in six common carp tissues (brain, heart, spleen, kidney, intestine, and gill revealed extensive functional divergence among the ABC genes. Different copies of some genes had tissue-specific expression patterns, which may indicate some gene function specialization. This study provides essential genomic resources for future studies in common carp.

Playware ABC 2: a Disruptive Technology for Global Development

DEFF Research Database (Denmark)

Lund, Henrik Hautop

2017-01-01

, anytime. The paper gives examples of how playware becomes a disruptive technology for global development, for instance in the health sector. For instance, in Tanzania doctors and community-based rehabilitation workers are constructing and combining modular playware tiles to easily create the right kind......The Playware ABC concept is used to create solutions that are usable by all kinds of users and contexts in our globalized society. In this paper, the Playware ABC can be exemplified with the development of the modular interactive tiles for health prevention and rehabilitation of anybody, anywhere...

The genusGuenthera Andr. in Bess. (Brassicaceae, Brassiceae

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Gómez-Campo, César

2003-12-01

Full Text Available A group of nine species -now included in Brassica— differ from all the other species in several characters, mainly in the stylar portion of their pistils always without seed primordia. Also in their branched subterranean stem (caudex with several leaf rosettes, their leaves entire to deeply pinnatifid but never pinnatisect, their shallowly notched cotyledons and their flattened, elliptic or ovoid seed contour. It is suggested to include these species under the generic denomination Guenthera Andr, in Bess. New ñames for the species and subspecies are provided, as well as a determination key for the species.Un grupo de nueve especies actualmente incluidas en Brassica difiere de todas las demás por varios caracteres, sobre todo por la porción estilar de sus pistilos, que siempre carece de primordios seminales. Además, por su tallo subterráneo ramificado, que forma un cáudex con varias rosetas; sus hojas de enteras hasta profundamente pinnatífidas, pero nunca pinnatisectas; sus cotiledones solo muy ligeramente escotados, y sus semillas, que tienden a ser elipsoidales o aplanadas. Se propone agruparlas todas bajo la denominación genérica Guenthera Andr, in Bess. Se detallan los nuevos nombres para las especies y Subespecies y se añade una clave para diferenciar las especies.

Estudio de la frecuencia de hemoglobinopatías en las islas de San Andrés y Providencia, Colombia

Directory of Open Access Journals (Sweden)

María del Pilar Bernal

1995-03-01

Full Text Available Se realizó un estudio destinado a determinar la frecuencia de hemoglobinopatías en las islas caribeñas de San Andrés y Providencia, en 544 individos individuos: 443 de San Andrés y 101 de Providencia. La frecuencia en San Andrés fue del 12,8% y en Providencia 20,8%; las hemoglobinopatías más frecuentes fueron: el rasgo falciforme, la hemoglobina C y la beta-talasemia. Los datos indican, que las hemoglobinopatías en esta región del país como problema de salud pública, tienen importancia y nos dan información sobre el origen geográfico de la población.

Book Review: America’s Blind Spot: Chávez, Oil and US Security by Andrés Cala and Michael Economides

DEFF Research Database (Denmark)

Boscan, Luis

2014-01-01

Review of: America’s Blind Spot: Chávez, Oil and US Security. Andrés Cala and Michael Economides. Continuum Books. 2012.......Review of: America’s Blind Spot: Chávez, Oil and US Security. Andrés Cala and Michael Economides. Continuum Books. 2012....

Analysis of cardiac autonomic modulation of children with attention deficit hyperactivity disorder

Directory of Open Access Journals (Sweden)

de Carvalho TD

2014-04-01

Full Text Available Tatiana Dias de Carvalho,1,2 Rubens Wajnsztejn,3 Luiz Carlos de Abreu,2,7 Luiz Carlos Marques Vanderlei,4 Moacir Fernandes Godoy,5 Fernando Adami,2 Vitor E Valenti,6 Carlos B M Monteiro,2,7 Claudio Leone,7 Karen Cristina da Cruz Martins,2 Celso Ferreira11Departamento de Medicina, Disciplina de Cardiologia, Universidade Federal de São Paulo, UNIFESP, São Paulo, Brazil; 2Laboratório de Escrita Científica da Faculdade de Medicina do ABC, FMABC, Santo André, Brazil; 3Núcleo Especializado em Aprendizagem, Programa de pós-graduação em Ciências da Saúde da Faculdade de Medicina do ABC, FMABC, Santo André, Brazil; 4Departamento de Fisioterapia da Faculdade de Ciências e Tecnologia, Universidade Estadual Paulista, UNESP, Presidente Prudente, São Paulo, Brazil; 5Núcleo Transdisciplinar de Estudos do Caos e da Complexidade. Faculdade de Medicina de São José de Rio Preto, FAMERP, São José do Rio Preto, Brazil; 6Departamento de Fonoaudiologia da Faculdade de Filosofia e Ciências, Universidade Estadual Paulista, UNESP, Marília, Brazil; 7Departamento de Saúde Materno-Infantil da Faculdade de Saúde Pública da Universidade de São Paulo, São Paulo, BrazilBackground: Attention deficit hyperactivity disorder (ADHD is characterized by decreased attention span, impulsiveness, and hyperactivity. Autonomic nervous system imbalance was previously described in this population. We aim to compare the autonomic function of children with ADHD and controls by analyzing heart rate variability (HRV.Methods: Children rested in supine position with spontaneous breathing for 20 minutes. Heart rate was recorded beat by beat. HRV analysis was performed in the time and frequency domains and Poincaré plot.Results: Twenty-eight children with ADHD (22 boys, aged 9.964 years and 28 controls (15 boys, age 9.857 years participated in this study. It was determined that the mean and standard deviation of indexes which indicate parasympathetic activity is higher in

mRMR-ABC: A Hybrid Gene Selection Algorithm for Cancer Classification Using Microarray Gene Expression Profiling

Directory of Open Access Journals (Sweden)

Hala Alshamlan

2015-01-01

Full Text Available An artificial bee colony (ABC is a relatively recent swarm intelligence optimization approach. In this paper, we propose the first attempt at applying ABC algorithm in analyzing a microarray gene expression profile. In addition, we propose an innovative feature selection algorithm, minimum redundancy maximum relevance (mRMR, and combine it with an ABC algorithm, mRMR-ABC, to select informative genes from microarray profile. The new approach is based on a support vector machine (SVM algorithm to measure the classification accuracy for selected genes. We evaluate the performance of the proposed mRMR-ABC algorithm by conducting extensive experiments on six binary and multiclass gene expression microarray datasets. Furthermore, we compare our proposed mRMR-ABC algorithm with previously known techniques. We reimplemented two of these techniques for the sake of a fair comparison using the same parameters. These two techniques are mRMR when combined with a genetic algorithm (mRMR-GA and mRMR when combined with a particle swarm optimization algorithm (mRMR-PSO. The experimental results prove that the proposed mRMR-ABC algorithm achieves accurate classification performance using small number of predictive genes when tested using both datasets and compared to previously suggested methods. This shows that mRMR-ABC is a promising approach for solving gene selection and cancer classification problems.

mRMR-ABC: A Hybrid Gene Selection Algorithm for Cancer Classification Using Microarray Gene Expression Profiling.

Science.gov (United States)

Alshamlan, Hala; Badr, Ghada; Alohali, Yousef

2015-01-01

An artificial bee colony (ABC) is a relatively recent swarm intelligence optimization approach. In this paper, we propose the first attempt at applying ABC algorithm in analyzing a microarray gene expression profile. In addition, we propose an innovative feature selection algorithm, minimum redundancy maximum relevance (mRMR), and combine it with an ABC algorithm, mRMR-ABC, to select informative genes from microarray profile. The new approach is based on a support vector machine (SVM) algorithm to measure the classification accuracy for selected genes. We evaluate the performance of the proposed mRMR-ABC algorithm by conducting extensive experiments on six binary and multiclass gene expression microarray datasets. Furthermore, we compare our proposed mRMR-ABC algorithm with previously known techniques. We reimplemented two of these techniques for the sake of a fair comparison using the same parameters. These two techniques are mRMR when combined with a genetic algorithm (mRMR-GA) and mRMR when combined with a particle swarm optimization algorithm (mRMR-PSO). The experimental results prove that the proposed mRMR-ABC algorithm achieves accurate classification performance using small number of predictive genes when tested using both datasets and compared to previously suggested methods. This shows that mRMR-ABC is a promising approach for solving gene selection and cancer classification problems.

Critérios para aplicação de ABC (Activity Based Costing na indústria naval Criteria for applying Activity Based Costing (ABC in the naval construction industry

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Nélio Achão Filho

2003-01-01

Full Text Available O presente trabalho tem por objetivo conceituar o que é ABC (Activity Based Costing e apresentar, de forma sistemática, uma sugestão de critérios para aplicação em empresa de construção naval. Basicamente, o estudo pretende contribuir, através do efeito demonstração do estudo de caso, para a conscientização quanto as dificuldades e oportunidades oferecidas pela implementação de um sistema ABC, numa área carente de novas metodologias gerenciais.The objective of this article is to evaluate what ABC (Activity Based Costing is, and to present, in a systematic form, a suggestion for the implantation of criteria for aplication at a naval construction company. Basically, the study intends, through the case study demo, make executives aware of the dificulties and oportunities offered by the implementation of an ABC system, in an area in need of new managerial methods.

Teresa Andrés y la organización Cultura Popular: una propuesta de coordinación bibliotecaria (1936-1938

Directory of Open Access Journals (Sweden)

Seguí i Francés, Romà

2011-12-01

Full Text Available Teresa Andrés Zamora es conocida por su actividad al frente de la Sección de Bibliotecas de Cultura Popular. Este trabajo describe las relaciones que se establecieron entre Teresa Andrés y Cultura Popular, tras hacerse cargo de las responsabilidades del Ministerio de Instrucción Pública.

ABCs of Oral Health: Nutrition - Children

Science.gov (United States)

... for gum inflammation and cavities. More ABCs of Oral Health A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | All Nutrition - Adults Nutrition - Children Home | InfoBites | Find a Dentist | ...

Revolver, kala ja harmoonia / Andres Tolts ; intervjueerinud Kadri Karro

Index Scriptorium Estoniae

Tolts, Andres, 1949-2014

2009-01-01

Andres Toltsi juubelinäitused Tallinnas: "Näitus" Tallinna Kunstihoones 25.9-25.10, "Asjad" Hobusepea galeriis 30.9-12.10, "Juubelinäitus" Haus galeriis 8.10-13.11. Kunstnik räägib oma loomingust, revolvri ja kala motiivist oma töödes, mõttekaaslusest, eestiaegsest maailmavaatest, harmooniast ja isikupärast kunstis ning elus, ilust ja inetusest, kaasaja kunstnike vajadusest oma loomingut sõnade abil seletada

Cutting edge SRU control : improved environmental compliance with Jacobs advanced burner control+ (ABC+)

Energy Technology Data Exchange (ETDEWEB)

Molenaar, G. [Jacobs Canada Inc., Calgary, AB (Canada); Henning, A.; Kobussen, S. [Jacobs Nederland BV, Hoogvliet (Netherlands)

2009-07-01

Oil sands bitumen contains approximately 4 to 5 per cent sulphur by weight and the bitumen is upgraded to produce lighter fractions. During coking the bitumen is heated and cracked into lighter molecules and a mixture of kerosene, naphtha and gas oil is recovered via fractionation. Then, the vapors leaving the fractionator are processed through hydrodesulphurization, followed by removal by amine based sweetening units. The acid gas from the ASUs is sent to the sulphur recovery units (SRUs) where most of the sulphur is recovered as elemental sulphur. The oil sands industry faces many challenges with respect to environmental impact, energy use and greenhouse gas emissions including the recovery of sulphur and minimizing hydrogen sulfide (H{sub 2}S) and sulphur dioxide (SO{sub 2}) emissions from the oil sands production facilities. In order to improve the SRU control response to acid gas feed variations, Jacobs Comprimo Sulphur Solutions implemented advanced burner control+ (ABC+) at Suncor's Simonette Gas Plant's SRU in northern Alberta. This control system used an acid gas feed analyzer and dynamic algorithms to control the combustion air to the reaction furnace. The analyzer measures H{sub 2}S, total hydrocarbons, carbon dioxide (CO{sub 2}) and water (H{sub 2}O) accurately and quickly, which is important for having effective and fast air-to-acid gas ratio control. The paper provided background information on the Suncor Simonette Gas Plant and discussed ABC+ versus conventional control. An overview of the simplified ABC and ABC+ systems was then illustrated and presented. The ABB multiwave process photometer was also explained. Last, a dynamic simulation of the potential benefits of ABC+ was discussed and the ABC+ benefits for oil sands were presented. It was concluded that ABC+ provides improved SRU performance, reduced SO{sub 2} emissions and violations, and reduced flaring. 1 tab., 3 figs.

Caracterização da clientela atendida no Núcleo de Psicologia Aplicada da Universidade Federal do Espírito Santo Profile of the clients assisted at "Núcleo de Psicologia Aplicada" (Applied Psychology Center of the Federal University of Espírito Santo

Directory of Open Access Journals (Sweden)

Rita de Cássia Ramos Louzada

2003-12-01

Full Text Available Este artigo apresenta o perfil da clientela do Núcleo de Psicologia Aplicada da Universidade Federal do Espírito Santo, de acordo com as seguintes variáveis: sexo, idade, renda familiar, escolaridade, local de moradia, ocupação, motivo da consulta e forma de encaminhamento. Com base nos dados encontrados são feitas reflexões em torno da estruturação deste tipo de serviço, suas articulações com os serviços de saúde mental da rede pública e a formação de psicólogos no âmbito do Estado do Espírito Santo.This article presents the profile of the clients assisted at "Núcleo de Psicologia Aplicada" of Federal University of Espírito Santo, according to the following variables: sex, age, family income, education, place of residence, occupation, reasons for consultation and types of assistance provided. Based on data obtained, some reflections are presented in regard to the organization of this kind of service, its relations with public mental health services and the professional preparation of psychologists in the state of Espírito Santo.

Tähelepanu, rahuldus, tähendusetus = Attention, satisfaction, meaninglessness / Raivo Kelomees

Index Scriptorium Estoniae

Kelomees, Raivo, 1960-

2015-01-01

Rahvusvaheline rühmanäitus "TL;DR" Tallinna Kunstihoone galeriis. Kuraator Stacey May Koosel. Digitaalkeskkonna ja infoliiasuse teemat vaagisid Varvara Guljajeva & Mar Canet, Pille Riin Jaik ja Eva Sepping läbi videoinstallatsioonide, Erki Kasemets ja Maris Karjatse fotoinstallatsiooniga, Sten Saarits heliinstallatsiooniga, Andres Lõo läbi heli ja stereograafia, Kiwa läbi trükisõna, Jesus Maria Rodriguez Santos grafitiga galerii akendel

Effects of the use of ABC weapons

International Nuclear Information System (INIS)

Karl-Rueckert, E.

1980-01-01

The effects of ABC-weapons are presented. The various classes of chemical weapons and their effects are discussed. It is pointed out that there is hardly a means of protection against these weapons. (MG) [de

An Efficient ABC_DE_Based Hybrid Algorithm for Protein–Ligand Docking

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Boxin Guan

2018-04-01

Full Text Available Protein–ligand docking is a process of searching for the optimal binding conformation between the receptor and the ligand. Automated docking plays an important role in drug design, and an efficient search algorithm is needed to tackle the docking problem. To tackle the protein–ligand docking problem more efficiently, An ABC_DE_based hybrid algorithm (ADHDOCK, integrating artificial bee colony (ABC algorithm and differential evolution (DE algorithm, is proposed in the article. ADHDOCK applies an adaptive population partition (APP mechanism to reasonably allocate the computational resources of the population in each iteration process, which helps the novel method make better use of the advantages of ABC and DE. The experiment tested fifty protein–ligand docking problems to compare the performance of ADHDOCK, ABC, DE, Lamarckian genetic algorithm (LGA, running history information guided genetic algorithm (HIGA, and swarm optimization for highly flexible protein–ligand docking (SODOCK. The results clearly exhibit the capability of ADHDOCK toward finding the lowest energy and the smallest root-mean-square deviation (RMSD on most of the protein–ligand docking problems with respect to the other five algorithms.

La vida de Santo Domingo de Silos: onirocrítica y semántica

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González, Javier Roberto

2007-12-01

Full Text Available We study the prophetic vision of Santo Domingo de Silos in Gonzalo de Berceo’s Vida de Santo Domingo de Silos, with the aim of: a analysing the text according to categories of prophecy, vision and dream in medieval christian culture; b analysing the configuration of oniric images as an allegorical discourse; c given the limits of allegorical semantics, interpreting those symbolic images characterized by prophetical obscuritas in the light of Grimaldus’ Vita Beati Dominici, source of Berceo’s Vida, and also in the light of medieval tradition of Other World visions and general chromatic an arithmetical symbolism, in order to establish semantic innovations and the proper meanning of Berceo’s text.Estudiamos la visión profética de Santo Domingo de Silos en la Vida de Santo Domingo de Silos de Gonzalo de Berceo, con el objeto de: a analizar el texto según las categorías de profecía, visión y sueño vigentes en la cultura cristiana medieval; b analizar la configuración de las imágenes oníricas como discurso alegórico; c dados los límites de la semántica alegórica, interpretar aquellas imágenes simbólicas caracterizadas por la obscuritas profética a la luz de la Vita Beati Dominici de Grimaldo, fuente de la Vida de Berceo, y también a la luz de la tradición medieval de las visiones de trasmundo y del simbolismo general cromático y aritmético, en orden al establecimiento de las innovaciones semánticas y con ellas del recto sentido del texto de Berceo.

Läänemere strateegia arvestab kodanike ettepanekutega / Jose Palma Andres ; interv. Erkki Bahovski

Index Scriptorium Estoniae

Palma Andres, Jose

2008-01-01

Euroopa Komisjoni regionaalpoliitika peadirektoraadi direktor Jose Palma Andres vastab küsimustele, mis puudutavad avalikku debatti Läänemere strateegia üle ning Venemaa partnerlust Läänemere strateegias. Lisa: [Läänemere strateegia

Glycolysis inhibition inactivates ABC transporters to restore drug sensitivity in malignant cells.

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Ayako Nakano

Full Text Available Cancer cells eventually acquire drug resistance largely via the aberrant expression of ATP-binding cassette (ABC transporters, ATP-dependent efflux pumps. Because cancer cells produce ATP mostly through glycolysis, in the present study we explored the effects of inhibiting glycolysis on the ABC transporter function and drug sensitivity of malignant cells. Inhibition of glycolysis by 3-bromopyruvate (3BrPA suppressed ATP production in malignant cells, and restored the retention of daunorubicin or mitoxantrone in ABC transporter-expressing, RPMI8226 (ABCG2, KG-1 (ABCB1 and HepG2 cells (ABCB1 and ABCG2. Interestingly, although side population (SP cells isolated from RPMI8226 cells exhibited higher levels of glycolysis with an increased expression of genes involved in the glycolytic pathway, 3BrPA abolished Hoechst 33342 exclusion in SP cells. 3BrPA also disrupted clonogenic capacity in malignant cell lines including RPMI8226, KG-1, and HepG2. Furthermore, 3BrPA restored cytotoxic effects of daunorubicin and doxorubicin on KG-1 and RPMI8226 cells, and markedly suppressed subcutaneous tumor growth in combination with doxorubicin in RPMI8226-implanted mice. These results collectively suggest that the inhibition of glycolysis is able to overcome drug resistance in ABC transporter-expressing malignant cells through the inactivation of ABC transporters and impairment of SP cells with enhanced glycolysis as well as clonogenic cells.

"Riigikogu hoone 90" = "Estonian parliament building 90" / Janno Roos, Andres Labi

Index Scriptorium Estoniae

Roos, Janno, 1976-

2013-01-01

Eesti Sisearhitektide Liidu 2012. aasta näituse kujunduse preemia pälvinud näitusest (Lossiplats 1A). Kujunduse autorid Janno Roos ja Andres Labi (Ruumilabor). Kuraator Mait Väljas. Graafiline disain: Identity. Sisearhitekti ja ESLi aastapreemiate žürii liikme Mari Kurismaa ning arhitektuuriajaloolase Leele Välja arvamused

SUTD-i koorik = SUTD Gridshell / Andres Sevtšuk, Raul Kalvo

Index Scriptorium Estoniae

Sevtšuk, Andres, 1981-

2013-01-01

Singapuri Tehnoloogia ja Disaini Ülikooli (SUTD) raamatukogu paviljon. Eskiis valmis esimese aasta üliõpilastele korraldatud töötoas. Algse ideega töötas edasi City Form Lab (arhitektid Andres Sevtšuk, Raul Kalvo). Paviljon pandi kokku ligi saja üliõpilase osalusel. Valmis: mai 2013

Baltoscandal on lõppenud, uued mõtted on saadud / Andres Keil

Index Scriptorium Estoniae

Keil, Andres, 1974-

2006-01-01

Eesti teater oli Baltoscandalil koondatud olematu teatri mõiste alla. Andres Noormetsa "Reunioon", Mart Kangro ja Ansambel U "Mäng", Marco Laimre "Vangistus", Asko Künnapi "Säälpool jõge", Anders Härmi "Cooking and Shitting", Sven Kuntu "Miks Eesti mehed ei tantsi?", Linnar Priimäe "Inimese lõhn"

Accuracy of the ABC/2 Score for Intracerebral Hemorrhage: Systematic Review and Analysis of MISTIE, CLEAR-IVH, and CLEAR III.

Science.gov (United States)

Webb, Alastair J S; Ullman, Natalie L; Morgan, Tim C; Muschelli, John; Kornbluth, Joshua; Awad, Issam A; Mayo, Stephen; Rosenblum, Michael; Ziai, Wendy; Zuccarrello, Mario; Aldrich, Francois; John, Sayona; Harnof, Sagi; Lopez, George; Broaddus, William C; Wijman, Christine; Vespa, Paul; Bullock, Ross; Haines, Stephen J; Cruz-Flores, Salvador; Tuhrim, Stan; Hill, Michael D; Narayan, Raj; Hanley, Daniel F

2015-09-01

The ABC/2 score estimates intracerebral hemorrhage (ICH) volume, yet validations have been limited by small samples and inappropriate outcome measures. We determined accuracy of the ABC/2 score calculated at a specialized reading center (RC-ABC) or local site (site-ABC) versus the reference-standard computed tomography-based planimetry (CTP). In Minimally Invasive Surgery Plus Recombinant Tissue-Type Plasminogen Activator for Intracerebral Hemorrhage Evacuation-II (MISTIE-II), Clot Lysis Evaluation of Accelerated Resolution of Intraventricular Hemorrhage (CLEAR-IVH) and CLEAR-III trials. ICH volume was prospectively calculated by CTP, RC-ABC, and site-ABC. Agreement between CTP and ABC/2 was defined as an absolute difference up to 5 mL and relative difference within 20%. Determinants of ABC/2 accuracy were assessed by logistic regression. In 4369 scans from 507 patients, CTP was more strongly correlated with RC-ABC (r(2)=0.93) than with site-ABC (r(2)=0.87). Although RC-ABC overestimated CTP-based volume on average (RC-ABC, 15.2 cm(3); CTP, 12.7 cm3), agreement was reasonable when categorized into mild, moderate, and severe ICH (κ=0.75; PABC (84% within 5 mL; 48% of scans within 20%) than for site-ABC (81% within 5 mL; 41% within 20%). RC-ABC had moderate accuracy for detecting ≥5 mL change in CTP volume between consecutive scans (sensitivity, 0.76; specificity, 0.86) and was more accurate with smaller ICH, thalamic hemorrhage, and homogeneous clots. ABC/2 scores at local or central sites are sufficiently accurate to categorize ICH volume and assess eligibility for the CLEAR-III and MISTIE III studies and moderately accurate for change in ICH volume. However, accuracy decreases with large, irregular, or lobar clots. URL: http://www.clinicaltrials.gov. Unique identifier: MISTIE-II NCT00224770; CLEAR-III NCT00784134. © 2015 American Heart Association, Inc.

Le journal de José Santos Vargas (1814-1825. 2: deux manuscrits

Directory of Open Access Journals (Sweden)

1997-01-01

Full Text Available L’existence de deux manuscrits différents du Journal de José Santos Vargas conduit à s’interroger sur la véracité de l’auteur. La comparaison entre les deux textes incite à attribuer le premier à une rédaction très proche de la fin de la guerre, et le second à un travail de collecte et de réécriture qui s’est étalé sur près de 30 ans. Entre le premier et le second manuscrit, se manifeste le changement du projet d’écriture de l’auteur qui évolue d’une conception individuelle de l’œuvre à l’idée de faire du Journal le recueil de toutes les traces de la guerre conservées dans les Vallées, et de le transformer en mémoire patriotique d’un microcosme provincial. EL DIARIO DE JOSÉ SANTOS VARGAS (1814-1825 - 2: DOS MANUSCRITOS. La existencia de dos manuscritos distintos del Diario del guerrillero José Santos Vargas incita a dudar de la veracidad del autor. La comparación entre los dos textos permite atribuir al primero una redacción próxima al fin de la guerra, mientras el segundo resulta de un trabajo de recolección y de reescritura que duró cerca de treinta años. Entre el primer y el segundo manuscrito, se manifiesta un cambio de proyecto de escritura por parte del autor que evoluciona de una concepción individualista de la obra hacia la idea de transformar el Diario en el compendio de todas las huellas de la guerra que se habían conservado en los Valles, transformándole en memoria patriótica de un microcosmos provincial. THE DIARY OF JOSÉ SANTOS VARGAS (1814-1825 - 2: TWO MANUSCRIPTS. The existence of two different manuscripts of the guerilla leader José Santos Vargas's Diary raises doubts about the truthfulness of the author. After comparing the two texts, it is possible to situate the writing of the first version in the time just after the war and the second version during a thirty year period in which testimonies and information were collected, and then rewritten. A change in the writing project of

Jacobsens ukendte samling af stensager fra den græske oldtid. Obsidian, økser, matricer, ansigtssten og andre sjældne oldsager

DEFF Research Database (Denmark)

Sørensen, Lasse

2012-01-01

Jacobsens ukendte samling af stensager fra den græske oldtid. Obsidian, økser, matricer, ansigtssten og andre sjældne oldsager......Jacobsens ukendte samling af stensager fra den græske oldtid. Obsidian, økser, matricer, ansigtssten og andre sjældne oldsager...

Una encrucijada incierta. Independentismo, anexionismo y abolición de la esclavitud en Santo Domingo, 1809-1821.

OpenAIRE

Jose Luis Belmonte Postigo

2015-01-01

La reintegración de Santo Domingo a la Monarquía española tuvo serias dificultades que amenazaron el asentamiento del sistema colonial español. La compleja situación política de la península, y la extensión del movimiento insurgente en los territorios continentales, supusieron obstáculos que imposibilitaron la remisión de los recursos que Santo Domingo demandaba. En mitad del marasmo económico, el auge de las ideas indepe...

The price of the natural gas in the producing states: Espirito Santo case; O preco do gas natural nos estados produtores: caso Espirito Santo

Energy Technology Data Exchange (ETDEWEB)

Cometi, Darcy Lannes

2008-07-01

The State of the Espirito Santo will become until the end of 2008, one of the main producers and natural gas exporters of Brazil, where, according to PETROBRAS, the State will produce about 20 million /day m{sup 3}, what it will go to contribute significantly for reduction of the dependence of the Bolivian gas, and still to give support to the natural gas sector in Brazil. The Intention of this work, is to identify proposals so that it has left of the gas produced in the State of the Espirito Santo, has a differentiated price. It does not make sensible the State to pay for the gas that is removed in its proper territory the same price that paid Sao Paulo for the gas that consumes imported of national Bolivia. With the markdown of the gas the State will be able to attract investments of great transport, to generate job and income and to advance in the question of the regional development that is of great importance for the developed cities less. Important to stand out that this study it will present proposals to try to sensitize PETROBRAS, initiating a quarrel on the subject. (author)

A test of the ABC model underlying rational emotive behavior therapy.

Science.gov (United States)

Ziegler, Daniel J; Leslie, Yvonne M

2003-02-01

The ABC model underlying Ellis's Rational Emotive Behavior Therapy predicts that people who think more irrationally should respond to daily stressors or hassles differently than do people who think less irrationally. This study tested this aspect of the ABC model. 192 college students were administered the Survey of Personal Beliefs and the Hassles Scale to measure irrational thinking and daily hassles, respectively. Students who scored higher on overall irrational thinking reported a significantly higher frequency of hassles than did those who scored lower on overall irrational thinking, while students who scored higher on awfulizing and low frustration tolerance reported a significantly greater intensity of hassles than did those who scored lower on awfulizing and low frustration tolerance. This indicates support for the ABC model, especially Ellis's construct of irrational beliefs central to this model.

Applying the Post-Modern Double ABC-X Model to Family Food Insecurity

Science.gov (United States)

Hutson, Samantha; Anderson, Melinda; Swafford, Melinda

2015-01-01

This paper develops the argument that using the Double ABC-X model in family and consumer sciences (FCS) curricula is a way to educate nutrition and dietetics students regarding a family's perceptions of food insecurity. The Double ABC-X model incorporates ecological theory as a basis to explain family stress and the resulting adjustment and…

San Andrés: Cotidianidad turística vs. idealismo desarrollista

Directory of Open Access Journals (Sweden)

José Ernesto Ramírez

1988-01-01

Full Text Available Pragmatic adaptation and idealistic intervention: An analytical description of development agencies within a context of political clientelism in San Andrés Island Colombia. (Tesis de doctorado en desarrollo. University Madison Wisconsin, 1980 Michael Jack Rosherg. University Microfilm Intemational. Ann Arbor, 1982, 301 págs. 6 ils. 40 cuadros.

The reproducibility of organ position using active breathing control (ABC) during liver radiotherapy

International Nuclear Information System (INIS)

Dawson, Laura A.; Brock, Kristy K.; Kazanjian, Sahira; Fitch, Dwight; McGinn, Cornelius J.; Lawrence, Theodore S.; Haken, Randall K. ten; Balter, James

2001-01-01

Purpose: To evaluate the intrafraction and interfraction reproducibility of liver immobilization using active breathing control (ABC). Methods and Materials: Patients with unresectable intrahepatic tumors who could comfortably hold their breath for at least 20 s were treated with focal liver radiation using ABC for liver immobilization. Fluoroscopy was used to measure any potential motion during ABC breath holds. Preceding each radiotherapy fraction, with the patient setup in the nominal treatment position using ABC, orthogonal radiographs were taken using room-mounted diagnostic X-ray tubes and a digital imager. The radiographs were compared to reference images using a 2D alignment tool. The treatment table was moved to produce acceptable setup, and repeat orthogonal verification images were obtained. The positions of the diaphragm and the liver (assessed by localization of implanted radiopaque intra-arterial microcoils) relative to the skeleton were subsequently analyzed. The intrafraction reproducibility (from repeat radiographs obtained within the time period of one fraction before treatment) and interfraction reproducibility (from comparisons of the first radiograph for each treatment with a reference radiograph) of the diaphragm and the hepatic microcoil positions relative to the skeleton with repeat breath holds using ABC were then measured. Caudal-cranial (CC), anterior-posterior (AP), and medial-lateral (ML) reproducibility of the hepatic microcoils relative to the skeleton were also determined from three-dimensional alignment of repeat CT scans obtained in the treatment position. Results: A total of 262 fractions of radiation were delivered using ABC breath holds in 8 patients. No motion of the diaphragm or hepatic microcoils was observed on fluoroscopy during ABC breath holds. From analyses of 158 sets of positioning radiographs, the average intrafraction CC reproducibility (σ) of the diaphragm and hepatic microcoil position relative to the skeleton

astroABC : An Approximate Bayesian Computation Sequential Monte Carlo sampler for cosmological parameter estimation

Energy Technology Data Exchange (ETDEWEB)

Jennings, E.; Madigan, M.

2017-04-01

Given the complexity of modern cosmological parameter inference where we arefaced with non-Gaussian data and noise, correlated systematics and multi-probecorrelated data sets, the Approximate Bayesian Computation (ABC) method is apromising alternative to traditional Markov Chain Monte Carlo approaches in thecase where the Likelihood is intractable or unknown. The ABC method is called"Likelihood free" as it avoids explicit evaluation of the Likelihood by using aforward model simulation of the data which can include systematics. Weintroduce astroABC, an open source ABC Sequential Monte Carlo (SMC) sampler forparameter estimation. A key challenge in astrophysics is the efficient use oflarge multi-probe datasets to constrain high dimensional, possibly correlatedparameter spaces. With this in mind astroABC allows for massive parallelizationusing MPI, a framework that handles spawning of jobs across multiple nodes. Akey new feature of astroABC is the ability to create MPI groups with differentcommunicators, one for the sampler and several others for the forward modelsimulation, which speeds up sampling time considerably. For smaller jobs thePython multiprocessing option is also available. Other key features include: aSequential Monte Carlo sampler, a method for iteratively adapting tolerancelevels, local covariance estimate using scikit-learn's KDTree, modules forspecifying optimal covariance matrix for a component-wise or multivariatenormal perturbation kernel, output and restart files are backed up everyiteration, user defined metric and simulation methods, a module for specifyingheterogeneous parameter priors including non-standard prior PDFs, a module forspecifying a constant, linear, log or exponential tolerance level,well-documented examples and sample scripts. This code is hosted online athttps://github.com/EliseJ/astroABC

Integrated management of operations in Santos Basin: methodology applied to a new philosophy of operations

Energy Technology Data Exchange (ETDEWEB)

Pereira, Leandro Leonardo; Lima, Claudio Benevenuto de Campos [Petroleo Brasileiro S.A. (PETROBRAS), Rio de Janeiro, RJ (Brazil); Derenzi Neto, Dario [Accenture, Rio de Janeiro, RJ (Brazil); Pinto, Vladimir Steffen [Soda IT, Rio de Janeiro, RJ (Brazil); Lima, Gilson Brito Alves [Universidade Federal Fluminense (UFF), Niteroi, RJ (Brazil)

2012-07-01

The objective of this paper is to present the methodology used to develop the Integrated Management of Operations (GIOp) project in Santos Basin Operational Unit (UO-BS) in the South-Southeast Exploration and Production area of PETROBRAS. The following text describes how the activities were carried out to gather improvements opportunities and to design To-Be processes, considering the challenging environment of the Santos Basin in the coming years. At the end of more than 12 months of work, more than 50 processes and sub-processes were redesigned, involving a multidisciplinary team in the areas of operations, maintenance, safety, health and environment, flow assurance, wells, reservoirs and planning. (author)

DEVELOPMENT OF A STRATEGIC MANAGEMENT TOOL IN A THERMAL POWER PLANT USING ABC AND BSC MODELS

Directory of Open Access Journals (Sweden)

Rishi Dwivedi

2016-05-01

Full Text Available In today’s dynamic, uncertain and highly competitive business environment, the long term success of an organization critically depends on the perceptions, choices and actions of its managers regarding their strategies. Activity based costing (ABC and balanced scorecard (BSC are the modern day management approaches acknowledged as reliable tools for strategy formulation and implementation in an organization. In this paper, ABC and BSC models are separately proposed and applied in the merry-go-round (MGR department of an Indian thermal power plant. The results elicited from adoption of these two models in the said power plant provide more accurate, timely, and reliable operational and financial information at different activity levels of the organization, which would help in effective strategic and tactical decision making. Even though, there are limited published research papers related to application of ABC model in power plants, none of them has adopted ABC and BSC techniques in an Indian contextual environment. Additionally, an integrated ABC-BSC model is designed to harness the complementary synergies of both ABC and BSC models.

Monetization non associated natural gas offshore reserve in the Espirito Santo Basin; Monetizacao de uma reserva 'offshore' de gas natural nao associado na Bacia do Espirito Santo

Energy Technology Data Exchange (ETDEWEB)

Kelman, Jose Ricardo; Barbosa, Leonardo Alcantara [BG Group, Rio de Janeiro, RJ (Brazil); Cintra, Marcos Antonio Lins da Costa [Agencia Nacional do Petroleo, Gas Natural e Biocombustiveis (ANP), Rio de Janeiro, RJ (Brazil); Brunet, Patricia Lima [Anadarko Exploracao e Producao Ltda., Rio de Janeiro, RJ (Brazil); Longo, Rafael Rodrigo [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil)

2008-07-01

This paper analyzes, from the perspective of a new player in the Brazilian market, the opportunities and the challenges to monetize a non-associated natural gas offshore resource, located in the Espirito Santo Basin. The fictitious exploration block 'BM-ES-07', located in shallow waters, near to the coast of Linhares, in Espirito Santo, was a hundred percent acquired, by an international independent oil and gas company during the fourth bid round of the ANP, occurred in 2002. With 10 (ten) billion cubic meters (m{sup 3}) of recoverable gas, the field will initiate its production in 2012, also producing condensate (C5+). The total investments are estimated (based in 2006 prices) in R$420 millions, including exploration, development and production costs. Considering the assumptions presented, the article describes the project development, presenting the economics results, and also discusses the alternatives for natural gas marketing. (author)

Tissue-specific transcript profiling for ABC transporters in the sequestering larvae of the phytophagous leaf beetle Chrysomela populi.

Directory of Open Access Journals (Sweden)

Anja S Strauss

Full Text Available Insects evolved ingenious adaptations to use extraordinary food sources. Particularly, the diet of herbivores enriched with noxious plant secondary metabolites requires detoxification mechanisms. Sequestration, which involves the uptake, transfer, and concentration of occasionally modified phytochemicals into specialized tissues or hemolymph, is one of the most successful detoxification strategies found in most insect orders. Due to the ability of ATP-binding cassette (ABC carriers to transport a wide range of molecules including phytochemicals and xenobiotics, it is highly likely that they play a role in this sequestration process. To shed light on the role of ABC proteins in sequestration, we describe an inventory of putative ABC transporters in various tissues in the sequestering juvenile poplar leaf beetle, Chrysomela populi.In the transcriptome of C. populi, we predicted 65 ABC transporters. To link the proteins with a possible function, we performed comparative phylogenetic analyses with ABC transporters of other insects and of humans. While tissue-specific profiling of each ABC transporter subfamily suggests that ABCB, C and G influence the plant metabolite absorption in the gut, ABCC with 14 members is the preferred subfamily responsible for the excretion of these metabolites via Malpighian tubules. Moreover, salicin, which is sequestered from poplar plants, is translocated into the defensive glands for further deterrent production. In these glands and among all identified ABC transporters, an exceptionally high transcript level was observed only for Cpabc35 (Cpmrp. RNAi revealed the deficiency of other ABC pumps to compensate the function of CpABC35, demonstrating its key role during sequestration.We provide the first comprehensive phylogenetic study of the ABC family in a phytophagous beetle species. RNA-seq data from different larval tissues propose the importance of ABC pumps to achieve a homeostasis of plant-derived compounds and

Noblessneri Loomemaja = Noblessner Creative house / Rasmus Tamme, Jaanus Saarepera, Eero Jürgenson, Andres Jomp

Index Scriptorium Estoniae

2015-01-01

Noblessneri Loomemaja Tallinnas Tööstuse 48/Peetri 11, valminud 2014. Arhitektid Rasmus Tamme, Jaanus Saarepera (ARS Projekt), sisearhitektid Eero Jürgenson, Andres Jomp (ARS Projekt). 2014. aasta Kultuurkapitali Arhitektuuripreemia kandidaat

Abjeção em textos de André Sant’Anna

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Leandro Salgueirinho

2009-07-01

Full Text Available Trata-se de uma leitura de textos do escritor André Sant’Anna a partir da problematização que, em The Return of the Real (1986, o crítico de arte norte-americano Hal Foster faz da noção de abjeto e da dita abject art.

Purification, crystallization and preliminary X-ray diffraction analysis of an archaeal ABC-ATPase

NARCIS (Netherlands)

Verdon, Grégory; Albers, Sonja-V.; Dijkstra, Bauke W.; Driessen, Arnold J.M.; Thunnissen, Andy-Mark W.H.

2002-01-01

In the archaeon Sulfolobus solfataricus glucose uptake is mediated by an ABC transport system. The ABC-ATPase of this transporter (GlcV) has been overproduced in Escherichia coli and purified. Crystals of GlcV suitable for data collection were obtained in the absence of nucleotide by microseeding

Andres Ehin tähistas sünnipäeva raamatuesitlusega / Maire Kõrver

Index Scriptorium Estoniae

Kõrver, Maire, 1961-

2006-01-01

Andres Ehin esitles oma luulekogu "Põdrapõrnikapääsukene" ja selle ingliskeelset tõlget "Moose Beetle Swallow" oma sünnipäeval Iiri suursaadiku residentsis, kus oli kohal ka luulekogu tõlkija, Iiri luuletaja Patrick Cotter

A educação hebraica segundo Theobaldo Miranda Santos

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Rodrigo Augusto de Souza

2015-01-01

Full Text Available Este trabalho tem por objetivo apresentar a educação hebraica segundo o pensamento de Theobaldo Miranda Santos (1904-1971. Para tanto, investigaremos o capítulo do manual didático “Noções de História da Educação” que tratou exclusivamente desse tema. Buscamos problematizar o tratamento oferecido pelo intelectual ao tema da educação hebraica. Considerando que Theobaldo publicou seu manual didático pela primeira vez em 1945, no período de hegemonia de ideologias como o fascismo e o nazismo, procuramos compreender as nuances da educação hebraica de acordo com seu pensamento. Essas ideologias demonstravam grande preocupação com a chamada “questão judaica”, que já havia sido apontada por Karl Marx (1818-1883 ainda durante o século XIX, na Alemanha. O surgimento do antissemitismo no plano político foi uma característica desse período histórico. O tratamento oferecido por Theobaldo Miranda Santos ao tema da educação hebraica consiste no objeto dessa investigação.

Panorama da fruticultura no Espírito Santo – Brasil

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Thiago Marques Teixeira Silva

2014-05-01

Full Text Available Resumo: A fruticultura é um mercado que vem já há alguns anos com um grande potencial tanto nacional quanto capixaba. Diante da situação, este trabalho tem o objetivo de apresentar um panorama da fruticultura no Espírito Santo, posicionando-a no cenário nacional. A partir do estudo da produção científica e de informações sobre o assunto, foi elaborada uma revisão bibliográfica a respeito do desenvolvimento da fruticultura capixaba. O setor de fruticultura está entre os principais geradores de renda, emprego e de desenvolvimento rural do estado. Na fruticultura agroecológica, tem-se como futuro desejável a expansão e a diversificação da atividade no Espírito Santo, com qualidade e competitividade. Contudo, a plena realização do potencial produtivo e social da fruticultura depende de uma melhor organização do setor, da modernização da comercialização e de incentivos para a inovação tecnológica e agregação de valor.

Tallinna idee / Andres Alver, Ott Alver, Marten Kaevats ; intervjueerinud Margit Mutso ; kommenteerinud Douglas Gordon

Index Scriptorium Estoniae

Alver, Andres, 1953-

2011-01-01

17. veebruaril esitleti raamatut "Tallinna idee", mis on koostatud Eesti Kunstiakadeemia 4. kursuse arhitektuuritudengite kursuseprojektide põhjal. Tallinna teemal vestlevad tudengid Ott Alver ja Marten Kaevats ning nende juhendaja professor Andres Alver

Design and skill assessment of an Operational Forecasting System for currents and sea level variability to the Santos Estuarine System - Brazil

Science.gov (United States)

Godoi Rezende Costa, C.; Castro, B. M.; Blumberg, A. F.; Leite, J. R. B., Sr.

2017-12-01

Santos City is subject to an average of 12 storm tide events per year. Such events bring coastal flooding able to threat human life and damage coastal infrastructure. Severe events have forced the interruption of ferry boat services and ship traffic through Santos Harbor, causing great impacts to Santos Port, the largest in South America, activities. Several studies have focused on the hydrodynamics of storm tide events but only a few of those studies have pursued an operational initiative to predict short term (operational forecasting system built to predict sea surface elevation and currents in the Santos Estuarine System and (ii) to evaluate model performance in simulating observed sea surface elevation. The Santos Operational Forecasting System (SOFS) hydrodynamic module is based on the Stevens Institute Estuarine and Coastal Ocean Model (sECOM). The fully automated SOFS is designed to provide up to 71 h forecast of sea surface elevations and currents every day. The system automatically collects results from global models to run the SOFS nested into another sECOM based model for the South Brazil Bight (SBB). Global forecasting results used to force both models come from Mercator Ocean, released by Copernicus Marine Service, and from the Brazilian developments on the Regional Atmospheric Modeling System (BRAMS) stablished by the Center for Weather Forecasts and Climate Studies (with Portuguese acronym CPTEC). The complete routines task take about 8 hours of run time to finish. SOFS was able to hindcast a severe storm tide event that took place in Santos on August 21-22, 2016. Comparisons with observed sea level provided skills of 0.92 and maximum root mean square errors of 25 cm. The good agreement with observed data shows the potential of the designed system to predict storm tides and to support both human and assets protection.

Transcriptomic insights on the ABC transporter gene family in the salmon louse Caligus rogercresseyi.

Science.gov (United States)

Valenzuela-Muñoz, Valentina; Sturm, Armin; Gallardo-Escárate, Cristian

2015-04-09

ATP-binding cassette (ABC) protein family encode for membrane proteins involved in the transport of various biomolecules through the cellular membrane. These proteins have been identified in all taxa and present important physiological functions, including the process of insecticide detoxification in arthropods. For that reason the ectoparasite Caligus rogercresseyi represents a model species for understanding the molecular underpinnings involved in insecticide drug resistance. llumina sequencing was performed using sea lice exposed to 2 and 3 ppb of deltamethrin and azamethiphos. Contigs obtained from de novo assembly were annotated by Blastx. RNA-Seq analysis was performed and validated by qPCR analysis. From the transcriptome database of C. rogercresseyi, 57 putative members of ABC protein sequences were identified and phylogenetically classified into the eight subfamilies described for ABC transporters in arthropods. Transcriptomic profiles for ABC proteins subfamilies were evaluated throughout C. rogercresseyi development. Moreover, RNA-Seq analysis was performed for adult male and female salmon lice exposed to the delousing drugs azamethiphos and deltamethrin. High transcript levels of the ABCB and ABCC subfamilies were evidenced. Furthermore, SNPs mining was carried out for the ABC proteins sequences, revealing pivotal genomic information. The present study gives a comprehensive transcriptome analysis of ABC proteins from C. rogercresseyi, providing relevant information about transporter roles during ontogeny and in relation to delousing drug responses in salmon lice. This genomic information represents a valuable tool for pest management in the Chilean salmon aquaculture industry.

Accelerator-based conversion (ABC) of weapons plutonium: Plant layout study and related design issues

International Nuclear Information System (INIS)

Cowell, B.S.; Fontana, M.H.; Krakowski, R.A.; Beard, C.A.; Buksa, J.J.; Davidson, J.W.; Sailor, W.C.; Williamson, M.A.

1995-01-01

In preparation for and in support of a detailed R and D Plan for the Accelerator-Based Conversion (ABC) of weapons plutonium, an ABC Plant Layout Study was conducted at the level of a pre-conceptual engineering design. The plant layout is based on an adaptation of the Molten-Salt Breeder Reactor (MSBR) detailed conceptual design that was completed in the early 1070s. Although the ABC Plant Layout Study included the Accelerator Equipment as an essential element, the engineering assessment focused primarily on the Target; Primary System (blanket and all systems containing plutonium-bearing fuel salt); the Heat-Removal System (secondary-coolant-salt and supercritical-steam systems); Chemical Processing; Operation and Maintenance; Containment and Safety; and Instrumentation and Control systems. Although constrained primarily to a reflection of an accelerator-driven (subcritical) variant of MSBR system, unique features and added flexibilities of the ABC suggest improved or alternative approaches to each of the above-listed subsystems; these, along with the key technical issues in need of resolution through a detailed R ampersand D plan for ABC are described on the bases of the ''strawman'' or ''point-of-departure'' plant layout that resulted from this study

Teresa Andrés Zamora (1907-1946: el compromiso social y político como arma de cultura

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Seguí i Francés, Romà

2010-12-01

Full Text Available La biografía de Teresa Andrés Zamora (Villalba de los Alcores, 1907- París, 1946 es un claro ejemplo de cómo el compromiso de una mujer republicana a través de la cultura se transformó en beligerancia política. Este artículo quiere mostrar una imagen de Teresa Andrés más profunda que la de una bibliotecaria que militó en el PCE, pretendiendo reconstruir su recorrido vital tanto en la faceta académica como profesional y política, con el objetivo de presentar una evolución que va desde su paso por la Residencia de Señoritas hasta su prematura muerte en París. Teresa Andrés Zamora representa una generación de mujeres republicanas que fue leal a la II República, trabajando incansablemente durante la Guerra Civil, y que padeció el exilio en una Francia ocupada.

Santos negros nas Américas na crise do Antigo Regime

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Caroline dos Santos Guedes

2014-12-01

Full Text Available Os objetos de estudo deste ensaio são a irmandade de São Baltasar em Buenos Aires e a irmandade de São Elesbão e Santa Efigênia no Rio de Janeiro de fins do século XVIII até princípios do século XIX. Ambas as instituições têm majoritariamente associados negros e contam também com santos negros como patronos. Observe-se a importância da apropriação da religião católica por estes afrodescendentes e o papel que esses “santos de cor” exercem no cotidiano desta população restrita de direitos devido à sua ascendência africana. As irmandades são instituições de suma importância na dinâmica colonial, então os negros se inserem nessas instituições ou criam suas próprias, muitas vezes na tentativa de penetrar no mundo social das colônias, ganhando maior visibilidade.

First phylogenetic analysis of dengue virus serotype 4 circulating in Espírito Santo state, Brazil, in 2013 and 2014.

Science.gov (United States)

Vicente, C R; Pannuti, C S; Urbano, P R; Felix, A C; Cerutti Junior, C; Herbinger, K-H; Fröschl, G; Romano, C M

2018-01-01

The purpose of the present study was to reconstruct the phylogeny of dengue virus serotype 4 (DENV-4) that was circulating in Espírito Santo state, Brazil, in 2013 and 2014, and to discuss the epidemiological implications associated with this evolutionary hypothesis. Partial envelope gene of eight DENV-4 samples from Espírito Santo state were sequenced and aligned with 72 worldwide DENV-4 reference sequences from GenBank. A phylogenetic tree was reconstructed through Bayesian Inference and the Time of the Most Recent Common Ancestor was estimated. The study detected the circulation of DENV-4 genotype II in Espírito Santo state, which was closely related to strains from the states of Mato Grosso collected in 2012 and of São Paulo sampled in 2015. This cluster emerged around 2011, approximately 4 years after the entry of the genotype II in Brazil through its northern states, possibly imported from Venezuela and Colombia. This is so far the first phylogenetic study of the DENV-4 circulating in Espírito Santo state and shows the importance of an internal route of dengue viral circulation in Brazil to the introduction of the virus into this state.

Giving Voice: Narrating silence, history and memory in André Brink ...

African Journals Online (AJOL)

This essay examines André Brink's two most recent novels, The Other Side of Silence (2002) and Before I Forget (2004), in terms of their voicing of silence and the rewriting of history and memory. Each has a theme familiar to Brink's readers – an historical story of colonial violence and violation avenged; and the recounting ...

Sensitive and specific fluorescent probes for functional analysis of the three major types of mammalian ABC transporters.

Science.gov (United States)

Lebedeva, Irina V; Pande, Praveen; Patton, Wayne F

2011-01-01

An underlying mechanism for multi drug resistance (MDR) is up-regulation of the transmembrane ATP-binding cassette (ABC) transporter proteins. ABC transporters also determine the general fate and effect of pharmaceutical agents in the body. The three major types of ABC transporters are MDR1 (P-gp, P-glycoprotein, ABCB1), MRP1/2 (ABCC1/2) and BCRP/MXR (ABCG2) proteins. Flow cytometry (FCM) allows determination of the functional expression levels of ABC transporters in live cells, but most dyes used as indicators (rhodamine 123, DiOC(2)(3), calcein-AM) have limited applicability as they do not detect all three major types of ABC transporters. Dyes with broad coverage (such as doxorubicin, daunorubicin and mitoxantrone) lack sensitivity due to overall dimness and thus may yield a significant percentage of false negative results. We describe two novel fluorescent probes that are substrates for all three common types of ABC transporters and can serve as indicators of MDR in flow cytometry assays using live cells. The probes exhibit fast internalization, favorable uptake/efflux kinetics and high sensitivity of MDR detection, as established by multidrug resistance activity factor (MAF) values and Kolmogorov-Smirnov statistical analysis. Used in combination with general or specific inhibitors of ABC transporters, both dyes readily identify functional efflux and are capable of detecting small levels of efflux as well as defining the type of multidrug resistance. The assay can be applied to the screening of putative modulators of ABC transporters, facilitating rapid, reproducible, specific and relatively simple functional detection of ABC transporter activity, and ready implementation on widely available instruments.

A Demanda do Santo Graal e seus entrecruzamentos

OpenAIRE

Luciana de Moraes Schenkel

2009-01-01

Este trabalho é um estudo comparativo entre dois romances de Chrétien de Troyes, Lancelot ou o cavaleiro da Charrete e Perceval ou o Romance do Graal e A Demanda do Santo Graal. Através desse estudo, pretende-se mostrar que a leitura de cada romance, separadamente, pode levar a enganos interpretativos, uma vez que não se considera o contexto geral em que as obras foram produzidas. Dessa forma, neste trabalho busca-se uma leitura mais completa dessas obras que se daria em três etapas: a leitur...

Les deux journaux de José Santos Vargas (1814-1825. 1: Problèmes d'édition

Directory of Open Access Journals (Sweden)

1995-01-01

Full Text Available La découverte du journal de guerre tenu par le guérillero José Santos Vargas a renouvelé nos connaissances sur l’histoire de la guerre d’indépendance dans le Haut Pérou. Cependant, le fait qu’il existe deux manuscrits différents de ce document, publiés tous deux par les soins de don Gunnar Mendoza, l’un en 1952 en Bolivie, l’autre en 1982 au Mexique, pose aux historiens des problèmes que les choix effectués par l’éditeur ont obscurcis. Cette première livraison d’un article qui devrait en comprendre deux remet en question la valeur scientifique de l’édition de 1982. LOS DOS DIARIOS DE JOSÉ SANTOS VARGAS. 1: PROBLEMAS EDITORIALES. El descubrimiento del diario de guerra redactado por el guerrillero José Santos Vargas ha renovado el conocimiento de la guerra de independencia en el Alto Perú. Pero el hecho de que existen dos manuscritos distintos de este documento, ambos publicados por don Gunnar Mendoza, uno en Bolivia en 1952 y otro en México en 1982, plantea a los historiadores problemas que las decisiones del editor han obscurecido. Esta primera entrega de un artículo que constará de dos, pone en tela de juicio el valor científico de la edición de 1982. THE TWO DIARIES OF JOSÉ SANTOS VARGAS. 1: PROBLEMS OF EDITION. The discovery of the diary of the guerillero leader José Santos Vargas add to our knowledge of the history of the independence war in the Alto Peru. However, the existence of two different manuscripts, both published by don Gunnar Mendoza, the first in Bolivia, 1952, the second in Mexico, 1982, present historians with problems that have been obscured by the editor’s choices. In this first part of the two parts article, we question the scientific value of the edition of 1982.

ABC transporters in Arthropods: genomic comparison and role in insecticide transport and resistance

NARCIS (Netherlands)

Dermauw, W.; Van Leeuwen, T.

2014-01-01

About a 100 years ago, the Drosophila white mutant marked the birth of Drosophila genetics. The white gene turned out to encode the first well studied ABC transporter in arthropods. The ABC gene family is now recognized as one of the largest transporter families in all kingdoms of life. The majority

The short version of the Activities-specific Balance Confidence (ABC) scale: its validity, reliability, and relationship to balance impairment and falls in older adults.

Science.gov (United States)

Schepens, Stacey; Goldberg, Allon; Wallace, Melissa

2010-01-01

A shortened version of the ABC 16-item scale (ABC-16), the ABC-6, has been proposed as an alternative balance confidence measure. We investigated whether the ABC-6 is a valid and reliable measure of balance confidence and examined its relationship to balance impairment and falls in older adults. Thirty-five community-dwelling older adults completed the ABC-16, including the 6 questions of the ABC-6. They also completed the following clinical balance tests: unipedal stance time (UST), functional reach (FR), Timed Up and Go (TUG), and maximum step length (MSL). Participants reported 12-month falls history. Balance confidence on the ABC-6 was significantly lower than on the ABC-16, however scores were highly correlated. Fallers reported lower balance confidence than non-fallers as measured by the ABC-6 scale, but confidence did not differ between the groups with the ABC-16. The ABC-6 significantly correlated with all balance tests assessed and number of falls. The ABC-16 significantly correlated with all balance tests assessed, but not with number of falls. Test-retest reliability for the ABC-16 and ABC-6 was good to excellent. The ABC-6 is a valid and reliable measure of balance confidence in community-dwelling older adults, and shows stronger relationships to falls than does the ABC-16. The ABC-6 may be a more useful balance confidence assessment tool than the ABC-16. Copyright 2009 Elsevier Ireland Ltd. All rights reserved.

Literatura y filosofía: Sartre, Martín-Santos y Bartleby

Directory of Open Access Journals (Sweden)

Santamaría Pargada, Antonio

2006-04-01

Full Text Available Luis Martín Santos has been, after his soon death, one of the most unfairly forgotten Spanish intellectuals. This situation happens to be even more unjust considering the success of his novel “Time of Silence” and his unfinished “Time of Destruction”. The works of this psychiatrist, philosophically formed in the existentialism tradition, tackle from psychiatric and medical studies to interpretations of Dilthey, Jaspers and Heidegger. Maybe the most important achievement made by Dr. Martín-Santos was the fact of pooling in his novels all the different fields he worked in, namely: existential philosophy, psychiatry and literature. This mutual influence leads to a clearly existential interpretation of the narrative subject and to a nihilist conception of freedom: the nothingness completely understood as Sartre did. And, consequently, the attractiveness of approaching the Spanish author through literary theories that are close to the French contemporary philosophy and the primacy, not only of the existential analysis in literature, but also of the influence of the literary character as a fiction that is able to create possible realities. That is why it is interesting to study “Bartleby the Scrivener” as a paradoxical example of the existential nothingness made flesh. To put it in a nutshell, the existential triviality, a sign of modern times, has been indeed very successfully portrayed by Martín-Santos.Luis Martín-Santos ha sido, tras su temprana muerte, uno de los grandes olvidados entre los intelectuales españoles del franquismo. Olvido especialmente injusto, teniendo en cuenta el éxito de su novela Tiempo de Silencio y su interesante proyecto inacabado Tiempo de Destrucción. La obra de este psiquiatra formado filosóficamente en el existencialismo abarca desde trabajos psiquiátricos relativos a la medicina hasta interpretaciones de Dilthey, Jaspers y Heidegger. Tal vez el mayor logro de Martín- Santos fuera el de aunar en sus

Evolutionary Pattern of N-Glycosylation Sequon Numbers  in Eukaryotic ABC Protein Superfamilies

Directory of Open Access Journals (Sweden)

R. Shyama Prasad Rao

2010-02-01

Full Text Available Many proteins contain a large number of NXS/T sequences (where X is any amino acid except proline which are the potential sites of asparagine (N linked glycosylation. However, the patterns of occurrence of these N-glycosylation sequons in related proteins or groups of proteins and their underlying causes have largely been unexplored. We computed the actual and probabilistic occurrence of NXS/T sequons in ABC protein superfamilies from eight diverse eukaryotic organisms. The ABC proteins contained significantly higher NXS/T sequon numbers compared to respective genome-wide average, but the sequon density was significantly lower owing to the increase in protein size and decrease in sequon specific amino acids. However, mammalian ABC proteins have significantly higher sequon density, and both serine and threonine containing sequons (NXS and NXT have been positively selected—against the recent findings of only threonine specific Darwinian selection of sequons in proteins. The occurrence of sequons was positively correlated with the frequency of sequon specific amino acids and negatively correlated with proline and the NPS/T sequences. Further, the NPS/T sequences were significantly higher than expected in plant ABC proteins which have the lowest number of NXS/T sequons. Accord- ingly, compared to overall proteins, N-glycosylation sequons in ABC protein superfamilies have a distinct pattern of occurrence, and the results are discussed in an evolutionary perspective.

Bryophytes from restinga in Setiba State Park, Espírito Santo State, Brazil

OpenAIRE

Visnadi, Sandra Regina; Vital, Daniel Moreira

1995-01-01

A total of 34 bryophyte species were identified (25 hepatics, 9 mosses) from restinga at Setiba State Park, Guarapari Municipality, Espírito Santo State, Brazil. Several species reported previously from restinga appear to be erroneous records, based on misidentification.

ABC transporters affect the elimination and toxicity of CdTe quantum dots in liver and kidney cells

Energy Technology Data Exchange (ETDEWEB)

Chen, Mingli; Yin, Huancai; Bai, Pengli [CAS Key Lab of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu 215163 (China); Miao, Peng [CAS Key Lab of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu 215163 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Deng, Xudong [Department of Chemical Engineering, McMaster University, Hamilton, Ontario, L8S 4L7 (Canada); Xu, Yingxue [CAS Key Lab of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu 215163 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Hu, Jun [CAS Key Lab of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu 215163 (China); Yin, Jian, E-mail: yinj@sibet.ac.cn [CAS Key Lab of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu 215163 (China)

2016-07-15

This paper aimed to investigate the role of adenosine triphosphate-binding cassette (ABC) transporters on the efflux and the toxicity of nanoparticles in liver and kidney cells. In this study, we synthesized CdTe quantum dots (QDs) that were monodispersed and emitted green fluorescence (maximum peak at 530 nm). Such QDs tended to accumulate in human hepatocellular carcinoma cells (HepG2), human kidney cells 2 (HK-2), and Madin-Darby canine kidney (MDCK) cells, and cause significant toxicity in all the three cell lines. Using specific inhibitors and inducers of P-glycoprotein (Pgp) and multidrug resistance associated proteins (Mrps), the cellular accumulation and subsequent toxicity of QDs in HepG2 and HK-2 cells were significantly affected, while only slight changes appeared in MDCK cells, corresponding well with the functional expressions of ABC transporters in cells. Moreover, treatment of QDs caused concentration- and time- dependent induction of ABC transporters in HepG2 and HK-2 cells, but such phenomenon was barely found in MDCK cells. Furthermore, the effects of CdTe QDs on ABC transporters were found to be greater than those of CdCl{sub 2} at equivalent concentrations of cadmium, indicating that the effects of QDs should be a combination of free Cd{sup 2+} and specific properties of QDs. Overall, these results indicated a strong dependence between the functional expressions of ABC transporters and the efflux of QDs, which could be an important reason for the modulation of QDs toxicity by ABC transporters. - Highlights: • ABC transporters contributed actively to the cellular efflux of CdTe quantum dots. • ABC transporters affected the cellular toxicity of CdTe quantum dots. • Treatment of CdTe quantum dots induced the gene expression of ABC transporters. • Free Cd{sup 2+} should be partially involved in the effects of QDs on ABC transporters. • Cellular efflux of quantum dots could be an important modulator for its toxicity.

IMG-ABC: A Knowledge Base To Fuel Discovery of Biosynthetic Gene Clusters and Novel Secondary Metabolites.

Science.gov (United States)

Hadjithomas, Michalis; Chen, I-Min Amy; Chu, Ken; Ratner, Anna; Palaniappan, Krishna; Szeto, Ernest; Huang, Jinghua; Reddy, T B K; Cimermančič, Peter; Fischbach, Michael A; Ivanova, Natalia N; Markowitz, Victor M; Kyrpides, Nikos C; Pati, Amrita

2015-07-14

In the discovery of secondary metabolites, analysis of sequence data is a promising exploration path that remains largely underutilized due to the lack of computational platforms that enable such a systematic approach on a large scale. In this work, we present IMG-ABC (https://img.jgi.doe.gov/abc), an atlas of biosynthetic gene clusters within the Integrated Microbial Genomes (IMG) system, which is aimed at harnessing the power of "big" genomic data for discovering small molecules. IMG-ABC relies on IMG's comprehensive integrated structural and functional genomic data for the analysis of biosynthetic gene clusters (BCs) and associated secondary metabolites (SMs). SMs and BCs serve as the two main classes of objects in IMG-ABC, each with a rich collection of attributes. A unique feature of IMG-ABC is the incorporation of both experimentally validated and computationally predicted BCs in genomes as well as metagenomes, thus identifying BCs in uncultured populations and rare taxa. We demonstrate the strength of IMG-ABC's focused integrated analysis tools in enabling the exploration of microbial secondary metabolism on a global scale, through the discovery of phenazine-producing clusters for the first time in Alphaproteobacteria. IMG-ABC strives to fill the long-existent void of resources for computational exploration of the secondary metabolism universe; its underlying scalable framework enables traversal of uncovered phylogenetic and chemical structure space, serving as a doorway to a new era in the discovery of novel molecules. IMG-ABC is the largest publicly available database of predicted and experimental biosynthetic gene clusters and the secondary metabolites they produce. The system also includes powerful search and analysis tools that are integrated with IMG's extensive genomic/metagenomic data and analysis tool kits. As new research on biosynthetic gene clusters and secondary metabolites is published and more genomes are sequenced, IMG-ABC will continue to

Korterelamu Tallinnas Weizenbergi 29 = Apartment Building in Tallinn, at 29 Weizenbergi Street / Andres Alver

Index Scriptorium Estoniae

Alver, Andres, 1953-

2001-01-01

Puitvoodriga betoonist kastjas hoone. Projekteerija Alver Trummal Arhitektid. Arhitektid Andres Alver ja Tarmo Laht. Eriosad: Eesti Projekt. Projekt 1998, valmis 2000. 3 ill.: põhiplaan, välisvaade, Pille Lausmäe kujundatud korteri vaade

Transportomics: screening for substrates of ABC transporters in body fluids using vesicular transport assays.

NARCIS (Netherlands)

Krumpochova, P; Sapthu, S.; Brouwers, J.F.H.M.; de Haas, M.; de Vos, R.; Borst, P.; van de Wetering, K.

2013-01-01

ABSTRACT The ATP-binding cassette (ABC) genes encode the largest family of transmembrane proteins. ABC transporters translocate a wide variety of substrates across membranes, but their physiological function is often incompletely understood. We describe a new method to study the substrate spectrum

Maramaa elust poksi ja graffitini / Andres Lepik, Ott Aardam ; interv. Gert Kiiler

Index Scriptorium Estoniae

Lepik, Andres

2008-01-01

Ugala teater alustas 89. hooaega. Esimese poole plaanitud esietendused : Toomas Suumani "Linnapea" Heiki Raudla raamatu "August Maramaa aeg" järgi, lavastaja Andres Lepik. Ott Aardami noortetükist "Poks", lavastaja autor. Gerald Sibleyras' "Grafiti", lavastaja Taago Tubin. Silvia Soro jõulunäidend "Inetu pardipoja" ainetel, lavastaja Oleg Titov

Dual repression of the multidrug efflux pump CmeABC by CosR and CmeR in Campylobacter jejuni

Directory of Open Access Journals (Sweden)

Tara Grinnage-Pulley

2016-07-01

Full Text Available During transmission and intestinal colonization, Campylobacter jejuni, a major foodborne human pathogen, experiences oxidative stress. CosR, a response regulator in C. jejuni, modulates the oxidative stress response and represses expression of the CmeABC multidrug efflux pump. CmeABC, a key component in resistance to toxic compounds including antimicrobials and bile salts, is also under negative regulation by CmeR, a TetR family transcriptional regulator. How CosR and CmeR interact in binding to the cmeABC promoter and how CosR senses oxidative stress are still unknown. To answer these questions, we conducted various experiments utilizing electrophoretic mobility shift assays and transcriptional fusion assays. CosR and CmeR bound independently to two separate sites of the cmeABC promoter, simultaneously repressing cmeABC expression. This dual binding of CosR and CmeR is optimal with a 17 base pair space between the two binding sites as mutations that shortened the distance between the binding sites decreased binding by CmeR and enhanced cmeABC expression. Additionally, the single cysteine residue (C218 of CosR was sensitive to oxidation, which altered the DNA-binding activity of CosR and dissociated CosR from the cmeABC promoter as determined by electrophoretic mobility shift assay. Replacement of C218 with serine rendered CosR insensitive to oxidation, suggesting a potential role of C218 in sensing oxidative stress and providing a possible mechanism for CosR-mediated response to oxidative stress. These findings reveal a dual regulatory role of CosR and CmeR in modulating cmeABC expression and suggest a potential mechanism that may explain overexpression of cmeABC in response to oxidative stress. Differential expression of cmeABC mediated by CmeR and CosR in response to different signals may facilitate adaptation of Campylobacter to various environmental conditions.

Genome-wide identification, characterization and phylogenetic analysis of 50 catfish ATP-binding cassette (ABC) transporter genes.

Science.gov (United States)

Liu, Shikai; Li, Qi; Liu, Zhanjiang

2013-01-01

Although a large set of full-length transcripts was recently assembled in catfish, annotation of large gene families, especially those with duplications, is still a great challenge. Most often, complexities in annotation cause mis-identification and thereby much confusion in the scientific literature. As such, detailed phylogenetic analysis and/or orthology analysis are required for annotation of genes involved in gene families. The ATP-binding cassette (ABC) transporter gene superfamily is a large gene family that encodes membrane proteins that transport a diverse set of substrates across membranes, playing important roles in protecting organisms from diverse environment. In this work, we identified a set of 50 ABC transporters in catfish genome. Phylogenetic analysis allowed their identification and annotation into seven subfamilies, including 9 ABCA genes, 12 ABCB genes, 12 ABCC genes, 5 ABCD genes, 2 ABCE genes, 4 ABCF genes and 6 ABCG genes. Most ABC transporters are conserved among vertebrates, though cases of recent gene duplications and gene losses do exist. Gene duplications in catfish were found for ABCA1, ABCB3, ABCB6, ABCC5, ABCD3, ABCE1, ABCF2 and ABCG2. The whole set of catfish ABC transporters provide the essential genomic resources for future biochemical, toxicological and physiological studies of ABC drug efflux transporters. The establishment of orthologies should allow functional inferences with the information from model species, though the function of lineage-specific genes can be distinct because of specific living environment with different selection pressure.

Evaluation of mercury, selenium and methylmercury in fish consumed by Santos Bay communities, Sao Paulo, Brazil

Energy Technology Data Exchange (ETDEWEB)

Farias, Luciana A.; Favaro, Deborah I.T. [Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil)]. E-mail: lufarias@usp.br; Azevedo, Juliana de S.; Braga, Elisabete S. [Sao Paulo Univ., SP (Brazil). Inst. Oceanografico. Lab. de Nutrientes, Micronutrientes e Tracos no Mar (LABNUT)]. E-mail: juliana@io.usp.br

2005-07-01

In the present study, mercury and selenium levels were evaluated in fish tissues and fish organs in the Santos Bay, Sao Paulo State, southeastern Brazil. Santos Bay waters are polluted by the large industrial complex of Cubatao. The estuary system filters part of this pollution before it reaches the Bay. Mercury and methylmercury determination were performed using Cold Vapor Atomic Absorption Spectrometry (CV-AAS) and selenium determination by Instrumental Neutron Activation Analysis (INAA). Methodology validation for the determination of these elements was carried out by means of reference materials analyses. There was no significant correlation between mercury and selenium concentrations (n = 17, (r2 ) R2 = 0.3482, p = 0.1709) in Cathorops spixii (bagre amarelo)- Ariidae family and Centropomus sp. (robalo)- Centropomidae family livers. Mercury and methylmercury concentrations in muscle from carnivorous species: Ariidae Cathorops spixii (bagre amarelo), Scianidae Steliffer rastifer (cangoa) and Scianidae Paralonchurus brasiliensis (maria-luiza) were determined and discussed. Total mercury concentration in Ariidae Catharops spixii livers presented the highest Hg level (7.6 mg kg-1). Although the Santos Bay is less contaminated than the inner section of its estuary system (Cubatao), it presents signs of environmental impact. (author)

Evaluation of mercury, selenium and methylmercury in fish consumed by Santos Bay communities, Sao Paulo, Brazil

International Nuclear Information System (INIS)

Farias, Luciana A.; Favaro, Deborah I.T.; Azevedo, Juliana de S.; Braga, Elisabete S.

2005-01-01

In the present study, mercury and selenium levels were evaluated in fish tissues and fish organs in the Santos Bay, Sao Paulo State, southeastern Brazil. Santos Bay waters are polluted by the large industrial complex of Cubatao. The estuary system filters part of this pollution before it reaches the Bay. Mercury and methylmercury determination were performed using Cold Vapor Atomic Absorption Spectrometry (CV-AAS) and selenium determination by Instrumental Neutron Activation Analysis (INAA). Methodology validation for the determination of these elements was carried out by means of reference materials analyses. There was no significant correlation between mercury and selenium concentrations (n = 17, (r2 ) R2 = 0.3482, p = 0.1709) in Cathorops spixii (bagre amarelo)- Ariidae family and Centropomus sp. (robalo)- Centropomidae family livers. Mercury and methylmercury concentrations in muscle from carnivorous species: Ariidae Cathorops spixii (bagre amarelo), Scianidae Steliffer rastifer (cangoa) and Scianidae Paralonchurus brasiliensis (maria-luiza) were determined and discussed. Total mercury concentration in Ariidae Catharops spixii livers presented the highest Hg level (7.6 mg kg-1). Although the Santos Bay is less contaminated than the inner section of its estuary system (Cubatao), it presents signs of environmental impact. (author)

A Transnational World Fractured but Not Forgotten: British West Indian Migration to the Colombian Islands of San Andrés and Providence

Directory of Open Access Journals (Sweden)

Sharika Crawford

2011-06-01

Full Text Available This article examines British West Indian migration to the Colombian archipelago of San Andrés and Providence in the late nineteenth to early twentieth century. While the United Fruit plantations, Panama Canal, oil fields in Venezuela, and railroad projects in Central America generated a strong demand for a large West Indian workforce, no such development took place on San Andrés and Providence. As a result, the profile of West Indian migration looks different than to the Spanish-speaking circum-Caribbean, with more professionals and merchants and fewer unskilled laborers. In the absence of mass migration, there was less hostility toward West Indian newcomers to San Andrés and Providence islands.

San Antonio-Espiritu Santo Bay, Texas Four band, 1meter resolution, UltraCam orthoimage

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The NOAA Office for Coastal Management purchased digital Vexcel Ultracam imagery and digital elevation models of the Texas coastline at Espiritu-Santo Bay in 2007....

Genome-wide analysis of the ATP-binding cassette (ABC) transporter gene family in the silkworm, Bombyx mori.

Science.gov (United States)

Xie, Xiaodong; Cheng, Tingcai; Wang, Genhong; Duan, Jun; Niu, Weihuan; Xia, Qingyou

2012-07-01

The ATP-binding cassette (ABC) superfamily is a larger protein family with diverse physiological functions in all kingdoms of life. We identified 53 ABC transporters in the silkworm genome, and classified them into eight subfamilies (A-H). Comparative genome analysis revealed that the silkworm has an expanded ABCC subfamily with more members than Drosophila melanogaster, Caenorhabditis elegans, or Homo sapiens. Phylogenetic analysis showed that the ABCE and ABCF genes were highly conserved in the silkworm, indicating possible involvement in fundamental biological processes. Five multidrug resistance-related genes in the ABCB subfamily and two multidrug resistance-associated-related genes in the ABCC subfamily indicated involvement in biochemical defense. Genetic variation analysis revealed four ABC genes that might be evolving under positive selection. Moreover, the silkworm ABCC4 gene might be important for silkworm domestication. Microarray analysis showed that the silkworm ABC genes had distinct expression patterns in different tissues on day 3 of the fifth instar. These results might provide new insights for further functional studies on the ABC genes in the silkworm genome.

A Quantitative Analysis of the Behavioral Checklist of the Movement ABC Motor Test

Science.gov (United States)

Ruiz, Luis Miguel; Gomez, Marta; Graupera, Jose Luis; Gutierrez, Melchor; Linaza, Jose Luis

2007-01-01

The fifth section of the Henderson and Sugden's Movement ABC Checklist is part of the general Checklist that accompanies The Movement ABC Battery. The authors maintain that the analysis of this section must be mainly qualitative instead of quantitative. The main objective of this study was to employ a quantitative analysis of this behavioural…

Film, ruum ja narratiiv : "Mis juhtus Andres Lapeteusega?" ning "Viini postmark" / Eva Näripea

Index Scriptorium Estoniae

Näripea, Eva, 1980-

2011-01-01

Analüüsitakse narratiivi aegruumi loomise viise juhtumi analüüsi vormis, vaadeldes kaht eesti mängufilmi : G. Kromanovi "Mis juhtus Andres Lapeteusega?" (Tallinnfilm, 1966) ja Veljo Käsperi "Viini postmark" (Tallinnfilm, 1967)

Film, ruum ja narratiiv : "Mis juhtus Andres Lapeteusega?" ning "Viini postmark" / Eva Näripea

Index Scriptorium Estoniae

Näripea, Eva

2006-01-01

Analüüsitakse narratiivi aegruumi loomise viise juhtumi analüüsi vormis, vaadeldes kaht eesti mängufilmi : G. Kromanovi "Mis juhtus Andres Lapeteusega?" (Tallinnfilm, 1966) ja Veljo Käsperi "Viini postmark" (Tallinnfilm, 1967)

The epidemiology and transmissibility of Zika virus in Girardot and San Andres island, Colombia, September 2015 to January 2016

Science.gov (United States)

Rojas, DP; Dean, NE; Yang, Y; Kenah, E; Quintero, J; Tomasi, S; Ramirez, EL; Kelly, Y; Castro, C; Carrasquilla, G; Halloran, ME; Longini, IM

2016-01-01

Transmission of Zika virus (ZIKV) was first detected in Colombia in September 2015. As of April 2016, Colombia had reported over 65,000 cases of Zika virus disease (ZVD). We analysed daily surveillance data of ZVD cases reported to the health authorities of San Andres and Girardot, Colombia, between September 2015 and January 2016. ZVD was laboratory-confirmed by reverse transcription-polymerase chain reaction (RT-PCR) in the serum of acute cases within five days of symptom onset. We use daily incidence data to estimate the basic reproductive number (R0) in each population. We identified 928 and 1,936 reported ZVD cases from San Andres and Girardot, respectively. The overall attack rate for reported ZVD was 12.13 cases per 1,000 residents of San Andres and 18.43 cases per 1,000 residents of Girardot. Attack rates were significantly higher in females in both municipalities (p < 0.001). Cases occurred in all age groups with highest rates in 20 to 49 year-olds. The estimated R0 for the Zika outbreak was 1.41 (95% confidence interval (CI): 1.15–1.74) in San Andres and 4.61 (95% CI: 4.11–5.16) in Girardot. Transmission of ZIKV is ongoing in the Americas. The estimated R0 from Colombia supports the observed rapid spread. PMID:27452806

Staggering in the cleavage pattern of E. coli ABC-excinuclease

International Nuclear Information System (INIS)

Myles, G.M.; Van Houten, B.; Sancar, A.

1986-01-01

E. coli ABC excinuclease is a complex of three proteins encoded by the uvrA, uvrB, and uvrC genes. The enzyme repairs DNA mono and diadducts by the single strand cleavage of DNA eight phosphodiester bond 5' and four or five phosphodiester bonds 3' to a DNA lesion and facilitates the removal of the resulting twelve or thirteen nucleotide fragment. In this study, the authors have investigated the excision pattern for ultraviolet (UV) induced diadducts, i.e. cyclobutane pyrimidine dimers and pyrimidine-pyrimidone (6-4) photoproducts. Terminally (5' or 3') labeled DNA was irradiated with 254nm UV and treated with ABC excinuclease before and after photoreactivation of cyclobutane dimers by E. coli DNA photolyase. In this way, the authors were able to differentiate between the cleavage pattern of pyrimidine dimers and of (6-4) photoproducts. Their results show that certain TT cyclobutane dimers and rare TT (6-4) photoproducts are excised by cleavage seven and, less frequently, six phosphodiester bonds to the 5' side of the DNA lesion in addition to the primary cutting site at the eight 5' phosphodiester bond. The 3' cleavage sites are maintained at the fourth and fifth phosphodiester bonds for the these UV induced lesions. These data indicate that the cleavage pattern of the ABC excinuclease may be dependent upon both the type of DNA lesion as well as it surrounding nucleotide sequence. In addition, the authors analysis shows that (6-4) photoproducts are much better substrates for ABC excinuclease than are pyrimidine dimers

ASPECTS OF OBSTACLES FOR APPLYING ACTIVITY BASED COSTING (ABC SYSTEM IN EGYPTIAN FIRMS

Directory of Open Access Journals (Sweden)

Petru STEFEA

2013-10-01

Full Text Available The following investigation aims to determine the aspects of obstacles for applying Activity Based Costing (ABC system in the Egyptian case and the significant differences among the effects of such obstacles . The Study used the survey method to describe and analyze the obstacles in some Egyptian firms. The population of the study is Egyptian manufacturing firms. This survey used the number of 392 questionnaires that were used throughout the total of 23 Egyptian manufacturing firms, during the first half of 2013. Finally, the study found some influencing obstacles for applying this system (ABC and there were significant differences among the aspects of obstacles for applying ABC system in the Egyptian manufacturing firms.

Exploration, Invention and Imagination: The Myth of Icarus in André Bazin

NARCIS (Netherlands)

Joret, B.; Viegas, S.; Teixeira, M.T.

2015-01-01

In this essay, I intend to elucidate the ontological implications of André Bazin’s integral realism: "a recreation of the world in its own image." The connection that he draws between the world and the image is in harmony with his mythical project for cinema, which argues that an imaginative myth

Plant ABC transporters enable many unique aspects of a terrestrial plant's lifestyle

DEFF Research Database (Denmark)

Hwang, Jae-Ung; Song, Won-Yong; Hong, Daewoong

2016-01-01

Terrestrial plants have two to four times more ATP-binding cassette (ABC) transporter genes than other organisms, including their ancestral microalgae. Recent studies found that plants harboring mutations in these transporters exhibit dramatic phenotypes, many of which are related to developmental...... to propose that diverse ABC transporters enabled many unique and essential aspects of a terrestrial plant's lifestyle, by transporting various compounds across specific membranes of the plant....

Reliability and validity of the German short version of the Activities specific Balance Confidence (ABC-D6) scale in older adults.

Science.gov (United States)

Schott, Nadja

2014-01-01

The Activities specific Balance Confidence (ABC) is a questionnaire which was developed to assess falls-associated self-efficacy. The aim of this study was to evaluate reliability and validity of the German abbreviated 6-item version of the ABC scores in community-dwelling older people. The study sample included 384 subjects (age 71.1 ± 9.7). In order to determine the psychometric properties, reliability and validity were assessed through administration of the German adaptation of the ABC-D16 to participants twice, 10 days apart, and comparison of the ABC-D16 and the ABC-D6 with functional measures of balance and mobility (one-leg stance; 10 m walk; TUG; Fullerton Advanced Balance Scale (FAB)), physical activity (Physical Activity Scale for the Elderly (PASE)), physical fitness (30s arm curl, 30s chair stand, 6 min walk), cognition (Trail-Making-Test (TMT)), falls status, and quality of life (SF36). Factor analyses suggested a 1-factor solution for the ABC-D6 scale (explained variance 79.8%). Internal consistency (.95) and test-retest reliability (.98) for the ABC-D6 scores were excellent. Scores on the ABC-D6 were significantly lower than on the ABC-D16, but ABC-D16 and ABC-D6 scores were highly correlated (.94). There was an increasing difference in the ABC-scores between men and women with increasing age. Fallers reported lower balance confidence than non-fallers. The ABC-D6 score significantly correlated with functional measures of balance and mobility, physical activity, physical fitness, cognition, and quality of life (-.698valid instrument to asses falls-associated self-efficacy and may be used in future research projects and clinical trials. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Tallinna Lennujaama kauba- ja tolliterminaal. Lennujaama 2, Tallinn / Andres Põime

Index Scriptorium Estoniae

Põime, Andres

1998-01-01

Kaubateeninduskeskuse puhul on tegemist suure, plaanimõõtudes 36x102 meetrise metallkonstruktsioonis, sandwich tüüpi paneelidega kaetud laohoonega, kus ühelt poolt tuuakse tollitav kaup lennukitelt sisse ja teiselt poolt viiakse tollitud kaup välja. Peatöövõtja : Normanni Linnagrupi AS. Ehitaja : Merko. Peaprojekteerija : K-Projekt. Arhitektuurne lahendus : Stuudio 3. Arhitekt Andres Põime ; töögrupp Vivian Oruvee, Tiiu Raudsepp, Reet Põime. Projekt 1997-98, valmis 1998.

Mida teeks tulevane kultuuriminister 500 miljoni krooniga? / interv. Andres Keil

Index Scriptorium Estoniae

2007-01-01

Suuremate erakondade kultuurispetsialistid (kultuuriministrikandidaadid) Urmas Paet, Andres Herkel, Peeter Jalakas, Indrek Saar, Jaak Allik, samuti kultuuriminister Raivo Palmaru vastavad küsimustele, mis on suurimad ohud eesti keele ja rahvuskultuuri säilimisele, milline on kultuuriministeeriumi ja -ministri portfelli staatus praeguses valitsuses, kas kultuuri rahastamine riigieelarvest on piisav, mille poolest erineb nende erakonna nägemus kultuuripoliitikast teiste erakondade omast, kuhu nad suunaksid 50, 500 miljonit, kui see oleks nende käsutuses

Seismic attributes characterization for Albian reservoirs in shallow Santos Basin

Energy Technology Data Exchange (ETDEWEB)

Vincentelli, Maria Gabriela C.; Barbosa, Mauro [HRT Petroleum, Rio de Janeiro, RJ (Brazil)

2008-07-01

The Santos basin southwest area is characterized by gas production, but it shows an exploratory problem due to the lack of good reservoirs facies. The main reservoirs are the Albian calcarenites, which show low porosities values (about 2%) in the northwest portion of the study area. From wire log analysis, it was interpreted that the porosity values can reach 15% at the south-west portion, both in the Caravela, Cavalo Marinho and Tubarao oil/gas fields and in the neighborhood of these fields. In order to find the best places to drill exploration wells at Shallow Santos, it is recommended to apply analyses of seismic attributes including: main average amplitude, energy, RMS, main amplitude, etc. Once the application of this methodology is restricted to 3D seismic data, in this study, a pseudo-3D seismic volume was built from 9,635 km of seismic lines, and 13 wells were used for reservoir facies control. As a result, the presence of good facies reservoirs in this area of the basin is restricted to trends with a NE-SW direction, and their presence is not only associated with the structural highs, this fact explains the dry wells over rollover structures. (author)

Santo remedio o la lógica de la realidad

Directory of Open Access Journals (Sweden)

Sheila Pastor

2015-12-01

Full Text Available Este artículo estudia Santo remedio, novela publicada por el escritor uruguayo Rafael Courtoisie en 2006, desde la perspectiva de diferentes teorías sobre la posmodernidad (Lyotard, Jameson. Una vez establecido el marco teórico que nos aportará las claves esenciales para enriquecer su interpretación, nos centraremos en el análisis de la obra, poniendo especial énfasis en sus particularidades estructurales y formales, marcadas por la influencia de los géneros audiovisuales. Por último, se ilustrará su potencial simbólico para mostrar la lógica que rige el universo narrativo de Courtoisie, caracterizado por la violencia y la fragmentación. This article aims to study Santo Remedio, novel published by the Uruguayan writer Rafael Courtoisie in 2006, from the perspective of different theories of postmodernism (Lyotard, Jameson. Once we have the theoretical framework that will give us the essential keys to enrich the interpretation, we focus on the analysis of the work, with emphasis on structural and formal characteristics, marked by the influence of audiovisual genres. Finally, we will illustrate its symbolic potential to show the logic that governs the narrative universe of Courtoisie, characterized by violence and fragmentation.

Simulation-based estimation of mean and standard deviation for meta-analysis via Approximate Bayesian Computation (ABC).

Science.gov (United States)

Kwon, Deukwoo; Reis, Isildinha M

2015-08-12

When conducting a meta-analysis of a continuous outcome, estimated means and standard deviations from the selected studies are required in order to obtain an overall estimate of the mean effect and its confidence interval. If these quantities are not directly reported in the publications, they must be estimated from other reported summary statistics, such as the median, the minimum, the maximum, and quartiles. We propose a simulation-based estimation approach using the Approximate Bayesian Computation (ABC) technique for estimating mean and standard deviation based on various sets of summary statistics found in published studies. We conduct a simulation study to compare the proposed ABC method with the existing methods of Hozo et al. (2005), Bland (2015), and Wan et al. (2014). In the estimation of the standard deviation, our ABC method performs better than the other methods when data are generated from skewed or heavy-tailed distributions. The corresponding average relative error (ARE) approaches zero as sample size increases. In data generated from the normal distribution, our ABC performs well. However, the Wan et al. method is best for estimating standard deviation under normal distribution. In the estimation of the mean, our ABC method is best regardless of assumed distribution. ABC is a flexible method for estimating the study-specific mean and standard deviation for meta-analysis, especially with underlying skewed or heavy-tailed distributions. The ABC method can be applied using other reported summary statistics such as the posterior mean and 95 % credible interval when Bayesian analysis has been employed.

La astronomía de un humanista, Juan Andrés

Directory of Open Access Journals (Sweden)

José Antonio SANDUVETE CHAVES

2009-11-01

Full Text Available RESUMEN: La páginas que siguen pretenden ofrecer una visión de conjunto del análisis que de la historia de la Astronomía realiza Juan Andrés, desde los orígenes de la humanidad hasta el siglo XVIII. Este análisis, incluido en su monumental obra Origen, progresos y estado actual de toda la literatura, destaca por su modernidad y precisión, constituyendo, por tanto, una interesante base de comparación entre la visión de la ciencia astronómica del humanismo ilustrado y la que pervive en la actualidad.ABSTRACT: The following pages attempt to offer a full view of the research into the history of astronomy made by Juan Andrés, from the beginning of human culture until the 18th century. This analysis, included in a broader work called Origen, progresos y estado de toda la literatura, stands out on account of its modern and precise ideas, thus representing an interesting knowledge base for comparing the view of astronomy during the Enlightenment with that of the present.

Informatização da rede de bibliotecas da Secretaria Municipal de Educação de Santos – SP Informatización de la red de bibliotecas de la Secretaría Municipal de Educación de Santos - SP.

Directory of Open Access Journals (Sweden)

Cláudio Souza Nunes

2011-06-01

Full Text Available Este artigo relata o processo de informatização da rede de Bibliotecas da Secretaria Municipal de Educação de Santos – SP (SEDUC, bem como a implantação do Personal Home Library – PHL82, que é uma aplicação Web, especialmente desenvolvida para administração de coleções e serviços de bibliotecas e centros de informações. A rede é composta de uma biblioteca central e 40 bibliotecas escolares, do 1° ao 9° ano do ensino fundamental, educação especial, educação de jovens e adultos (EJA e ensino técnico profissionalizante. Considera que a implantação do sistema coloca as bibliotecas escolares da Secretaria Municipal de Santos nos moldes de importantes instituições de pesquisa do país, possibilitando a formação de uma rede de informação bibliográfica escolar da Prefeitura de Santos.

75 FR 11991 - ABC & D Recycling, Inc.-Lease and Operation Exemption-a Line of Railroad in Ware, MA

Science.gov (United States)

2010-03-12

... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [STB Finance Docket No. 35356] ABC & D Recycling, Inc.--Lease and Operation Exemption--a Line of Railroad in Ware, MA ABC & D Recycling, Inc. (ABC & D), a noncarrier, has filed a verified notice of exemption under 49 CFR 1150.31 to lease from O...

New Enhanced Artificial Bee Colony (JA-ABC5 Algorithm with Application for Reactive Power Optimization

Directory of Open Access Journals (Sweden)

Noorazliza Sulaiman

2015-01-01

Full Text Available The standard artificial bee colony (ABC algorithm involves exploration and exploitation processes which need to be balanced for enhanced performance. This paper proposes a new modified ABC algorithm named JA-ABC5 to enhance convergence speed and improve the ability to reach the global optimum by balancing exploration and exploitation processes. New stages have been proposed at the earlier stages of the algorithm to increase the exploitation process. Besides that, modified mutation equations have also been introduced in the employed and onlooker-bees phases to balance the two processes. The performance of JA-ABC5 has been analyzed on 27 commonly used benchmark functions and tested to optimize the reactive power optimization problem. The performance results have clearly shown that the newly proposed algorithm has outperformed other compared algorithms in terms of convergence speed and global optimum achievement.

New enhanced artificial bee colony (JA-ABC5) algorithm with application for reactive power optimization.

Science.gov (United States)

Sulaiman, Noorazliza; Mohamad-Saleh, Junita; Abro, Abdul Ghani

2015-01-01

The standard artificial bee colony (ABC) algorithm involves exploration and exploitation processes which need to be balanced for enhanced performance. This paper proposes a new modified ABC algorithm named JA-ABC5 to enhance convergence speed and improve the ability to reach the global optimum by balancing exploration and exploitation processes. New stages have been proposed at the earlier stages of the algorithm to increase the exploitation process. Besides that, modified mutation equations have also been introduced in the employed and onlooker-bees phases to balance the two processes. The performance of JA-ABC5 has been analyzed on 27 commonly used benchmark functions and tested to optimize the reactive power optimization problem. The performance results have clearly shown that the newly proposed algorithm has outperformed other compared algorithms in terms of convergence speed and global optimum achievement.

POLÍTICAS PÚBLICAS URBANAS: o caso do centro de Santos

Directory of Open Access Journals (Sweden)

André da Rocha Santos

2008-01-01

Full Text Available This article evaluates the process of the urban revitalization center of Santos. Its ́ analysis object is the Centro, Paquetá, Vila Nova, Valongo and part of Vila Mathias neighborhoods. Its ́ objective is to describe the mentioned process since the approval of the 1998 Managing Plan until the current days. The introduction points out the municipal public power ́s and planning secretariat ́s role in the conduction of the public policies involving these areas. The second section of this article analyses certain aspects of the "Alegra Centro Program" which ́s objective is to support the enterprises implantation and the functioning activities directed to commerce and the tourism, among the evaluation of the urban landscape and the cultural local patrimony. The third part of this paper deals with the public power ́s projects and interventions developed and spread through marketing actions. This article ́s fourth section shows the general housing matter in the central area and its ́ precarious situation. Finally, the conclusion evaluates the process of urban revitalization of the Brazilian city of Santos and the city ́s habitation policies.

Myrtaceae da restinga no norte do Espírito Santo, Brasil

Directory of Open Access Journals (Sweden)

Augusto Giaretta

2015-01-01

Full Text Available Myrtaceae está entre as famílias mais ricas em espécies nas restingas do Espírito Santo. Este estudo objetivou fazer o inventário e a caracterização das espécies de Myrtaceae ocorrentes na vegetação de restinga no norte do Espírito Santo. Foram registradas 52 espécies distribuídas em 10 gêneros. O gênero mais representado foi Eugenia (19 espécies, seguido de Myrcia (12, Marlierea (6, Psidium (4, Myrciaria (3, Calyptranthes (2, Campomanesia (2, Neomitranthes (2, Blepharocalyx (1 e Plinia (1. Foram registradas duas  espécies endêmicas (Eugenia inversa e Myrcia limae. As formações vegetais  com maior número de espécies foram a florestal não inundável (40 espécies,  seguida da arbustiva fechada não inundável (19 e florestal inundável (19. São apresentadas chaves para identificação das espécies, descrições, comentários,  distribuição geográfica e ilustrações dos caracteres diagnósticos.

Evidence for an ABC-Type Riboflavin Transporter System in Pathogenic Spirochetes

Science.gov (United States)

Deka, Ranjit K.; Brautigam, Chad A.; Biddy, Brent A.; Liu, Wei Z.; Norgard, Michael V.

2013-01-01

ABSTRACT Bacterial transporter proteins are involved in the translocation of many essential nutrients and metabolites. However, many of these key bacterial transport systems remain to be identified, including those involved in the transport of riboflavin (vitamin B2). Pathogenic spirochetes lack riboflavin biosynthetic pathways, implying reliance on obtaining riboflavin from their hosts. Using structural and functional characterizations of possible ligand-binding components, we have identified an ABC-type riboflavin transport system within pathogenic spirochetes. The putative lipoprotein ligand-binding components of these systems from three different spirochetes were cloned, hyperexpressed in Escherichia coli, and purified to homogeneity. Solutions of all three of the purified recombinant proteins were bright yellow. UV-visible spectra demonstrated that these proteins were likely flavoproteins; electrospray ionization mass spectrometry and thin-layer chromatography confirmed that they contained riboflavin. A 1.3-Å crystal structure of the protein (TP0298) encoded by Treponema pallidum, the syphilis spirochete, demonstrated that the protein’s fold is similar to the ligand-binding components of ABC-type transporters. The structure also revealed other salient details of the riboflavin binding site. Comparative bioinformatics analyses of spirochetal genomes, coupled with experimental validation, facilitated the discovery of this new ABC-type riboflavin transport system(s). We denote the ligand-binding component as riboflavin uptake transporter A (RfuA). Taken together, it appears that pathogenic spirochetes have evolved an ABC-type transport system (RfuABCD) for survival in their host environments, particularly that of the human host. PMID:23404400

Andres Herkel : Venemaa esindaja ENPA presidendiks ei sobi / Haldi Ellam, Ravil Khair Al-Din

Index Scriptorium Estoniae

Ellam, Haldi

2007-01-01

Vene ajalehe Kommersant väitel on Eesti parlamendi süüdistused ENPA presidendi Rene van der Lindeni vastu seotud Mihhail Margelovi võimaliku valimisega uueks presidendiks. Kristiina Ojuland ja Andres Herkel lükkavad väite tagasi

Geología y aspectos geográficos de la isla de san andrés, colombia

OpenAIRE

Vargas Cuervo, German

2012-01-01

La Isla de San Andrés ha sido definida geológicamente por varios autores en dos unidades calcáreas de características bien marcadas: Una unidad de calizas heterogéneas,denominada como Formación San Andrés de edad Mioceno y una unidad de calizas coralinas de edad Pleistoceno, conocida como Formación San Luis. La primera unidad aflora en la parte central de la isla y representa la zona de colinas suaves con alturas máximas de 87 m.s.n.m y la Formación San Luis constituye la región plana a suave...

AND/R: Advanced neutron diffractometer/reflectometer for investigation of thin films and multilayers for the life sciences

International Nuclear Information System (INIS)

Dura, Joseph A.; Pierce, Donald J.; Majkrzak, Charles F.; Maliszewskyj, Nicholas C.; McGillivray, Duncan J.; Loesche, Mathias; O'Donovan, Kevin V.; Mihailescu, Mihaela; Perez-Salas, Ursula; Worcester, David L.; White, Stephen H.

2006-01-01

An elastic neutron scattering instrument, the advanced neutron diffractometer/reflectometer (AND/R), has recently been commissioned at the National Institute of Standards and Technology Center for Neutron Research. The AND/R is the centerpiece of the Cold Neutrons for Biology and Technology partnership, which is dedicated to the structural characterization of thin films and multilayers of biological interest. The instrument is capable of measuring both specular and nonspecular reflectivity, as well as crystalline or semicrystalline diffraction at wave-vector transfers up to approximately 2.20 A -1 . A detailed description of this flexible instrument and its performance characteristics in various operating modes are given

Lønsomheds- eller rentabilitetsmodeller: hvilke modeller findes, og hvad er forudsætningerne for et godt udgangspunkt? - når økonomistyringen skal analyseres baglæns for at planlægge fremtiden

DEFF Research Database (Denmark)

Nielsen, Steen

2005-01-01

rentabilitetsanalyser af det forgangne år. Ja, ledere og andres løn afhænger ofte af denne opgørelse. Men også i relation til ABC udviklede Kaplan m.fl. hierarkiske modeller - også kaldet Activity-based Costing Profitability Analysis (ABPA), hvor analysen foregår på styk, serie, produkttype og overordnet niveau. Ikke...

ELISABETH DE SCHÓNAU: AUTORIDAD VISIONARIA Y LA PRESENCIA DE LOS SANTOS

Directory of Open Access Journals (Sweden)

María Eugenia Góngora

2007-11-01

Full Text Available En este ensayo quiero explorar algunas características de Elisabeth de Schónau( 1129-1164 como escritora visionaria, y mostrar cómo su obra sobre el martirio de Santa Úrsula, el Liber revelationum Elisabeth de sacro exercitu virginum Coloniensium (Libro de las revelaciones de Elisabeth sobre el santo ejército de vírgenes de Colonia, escrita después de 1156 y ampliamente leída y difundida entre sus contemporáneos, puede ilustrar algunos usos de la autoridad visionaria en el ámbito del culto a los santos y sus reliquiasIn this essay I would like to explore the visionary writings of Elisabeth of Schbnau (1129-1164 and to show how her work on Saint Ursula's martyrdom in Cologne, the Liber revelationum Elisabeth de sacro exercitu virginum Coloniensium (The book of Revelations on the sacred army of Cologne, written after 1156 and very widely read among her contemporaries, can illustrate some uses of visionary authority in the context of the cult of the saints and their relics

Inventory and general analysis of the ATP-binding cassette (ABC) gene superfamily in maize (Zea mays L.).

Science.gov (United States)

Pang, Kaiyuan; Li, Yanjiao; Liu, Menghan; Meng, Zhaodong; Yu, Yanli

2013-09-10

The metabolic functions of ATP-binding cassette (or ABC) proteins, one of the largest families of proteins presented in all organisms, have been investigated in many protozoan, animal and plant species. To facilitate more systematic and complicated studies on maize ABC proteins in the future, we present the first complete inventory of these proteins, including 130 open reading frames (ORFs), and provide general descriptions of their classifications, basic structures, typical functions, evolution track analysis and expression profiles. The 130 ORFs were assigned to eight subfamilies based on their structures and homological features. Five of these subfamilies consist of 109 proteins, containing transmembrane domains (TM) performing as transporters. The rest three subfamilies contain 21 soluble proteins involved in various functions other than molecular transport. A comparison of ABC proteins among nine selected species revealed either convergence or divergence in each of the ABC subfamilies. Generally, plant genomes contain far more ABC genes than animal genomes. The expression profiles and evolution track of each maize ABC gene were further investigated, the results of which could provide clues for analyzing their functions. Quantitative real-time polymerase chain reaction experiments (PCR) were conducted to detect induced expression in select ABC genes under several common stresses. This investigation provides valuable information for future research on stress tolerance in plants and potential strategies for enhancing maize production under stressful conditions. Copyright © 2013 Elsevier B.V. All rights reserved.

Teresa y Luis, Luis y Teresa. Dos santos en tiempos recios

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Emilio Callado Estela

2016-06-01

Full Text Available El presente artículo analiza la relación entre dos grandes santos españoles de la Contrarreforma Católica, Teresa de Jesús y el dominico fray Luis Bertrán. The present article analyses the relation between two big Spanish saints of the Catholic Counterreformation, Teresa de Jesus and the Dominican monk Luis Bertrán.

2000 annual report of Espirito Santo Centrais Eletricas S. A. - ESCELSA

International Nuclear Information System (INIS)

2000-01-01

This document reports the activities of the Espirito Santo Electric Power Plants, Brazil, during the year 2000. The document presents figures on economic and financial, market, human resources, and indicators of the operating margin, personnel plus third party services and net operating revenue, energy losses, equivalent outage duration per customer, equivalent frequency outage per customer, average service response time and the number of customers per employee

The Role of Activity Based Costing (ABC) in Educational Support Services: A White Paper.

Science.gov (United States)

Edds, Daniel B.

Many front-line managers who are assuming more financial responsibility for their organizations find traditional cost accounting inadequate for their needs and are turning to Activity Based Costing (ABC). ABC is not a financial reporting system to serve the needs of regulatory agencies, but a tool that tracks costs from the general ledger…

Transcriptional expression analysis of ABC efflux transporters and xenobiotic-metabolizing enzymes in the Chinese rare minnow.

Science.gov (United States)

Yuan, Lilai; Lv, Biping; Zha, Jinmiao; Wang, Zijian

2014-05-01

In the present study, the cDNA fragments of five ABC transporter genes (ABCB1, ABCB11, ABCC1, ABCC2, and ABCG2) in the rare minnow were cloned, and their tissue-specific expression patterns were evaluated across eight rare minnow tissues (liver, gill, intestine, kidney, spleen, brain, skin, and muscle). Furthermore, the transcriptional effects on these ABC transporter genes and five xenobiotic-metabolizing enzyme genes (CYP1A, GSTm, GSTp1, GCLC, and UGT1a) were determined in the rare minnow liver after 12 days of pyrene exposure. Basal expression analysis showed that the tissues with high expression of the ABC transporters included the liver, kidney, and intestine. Moreover, the most highly expressed of the ABC genes were ABCB1 and ABCC2 in all eight of the tissues tested. The ABCB11 gene was almost exclusively expressed in the liver of the rare minnow, whereas ABCC1 and ABCG2 showed weak expression in all eight tissues compared to ABCB1 and ABCC2. Our results provide the first thorough examination of the expression patterns of toxicologically relevant ABC transporters in the rare minnow and serve as a necessary basis for further studies of these ABC transporters in fish. Furthermore, synergistic up-regulation of CYP1A, GSTp1, GCLC, UGT1a, and ABCC2 was observed in the rare minnow liver following pyrene exposure, while GSTm, ABCB1, ABCB11, ABCC1, and ABCG2 were not significantly affected (p ABC transporters by pyrene suggests a possible involvement and cooperation of these genes in the detoxification process in rare minnows. Copyright © 2014 Elsevier B.V. All rights reserved.

Assessment of the ABC/2 Method of Epidural Hematoma Volume Measurement as Compared to Computer-Assisted Planimetric Analysis.

Science.gov (United States)

Hu, Ting-Ting; Yan, Ling; Yan, Peng-Fei; Wang, Xuan; Yue, Ge-Fen

2016-01-01

Epidural hematoma volume (EDHV) is an independent predictor of prognosis in patients with epidural hematoma (EDH) and plays a central role in treatment decision making. This study's objective was to determine the accuracy and reliability of the widely used volume measurement method ABC/2 in estimating EDHV by comparing it to the computer-assisted planimetric method. A data set of computerized tomography (CT) scans of 35 patients with EDH was evaluated to determine the accuracy of ABC/2 method, using computer-assisted planimetric technique to establish the reference criterion of EDHV for each patient. Another data set was constructed by randomly selecting 5 patients then replicating each case twice to yield 15 patients. Intra- and interobserver reliability were evaluated by asking four observers to independently estimate EDHV for the latter data set using the ABC/2 method. Estimation of EDHV using the ABC/2 method showed high intra- and interobserver reliability (intra-class correlation coefficient = .99). These estimates were closely correlated with planimetric measures (r = .99). But the ABC/2 method generally overestimated EDHV, especially in the nonellipsoid-like group. The difference between the ABC/2 measures and planimetric measures was statistically significant (p ABC/2 method could be used for EDHV measurement, which would contribute to treatment decision making as well as clinical outcome prediction. However, clinicians should be aware that the ABC/2 method results in a general volume overestimation. Future studies focusing on justification of the technique to improve its accuracy would be of practical value. © The Author(s) 2015.

Effect of SOS-induced levels of imuABC on spontaneous and damage-induced mutagenesis in Caulobacter crescentus.

Science.gov (United States)

Alves, Ingrid R; Lima-Noronha, Marco A; Silva, Larissa G; Fernández-Silva, Frank S; Freitas, Aline Luiza D; Marques, Marilis V; Galhardo, Rodrigo S

2017-11-01

imuABC (imuAB dnaE2) genes are responsible for SOS-mutagenesis in Caulobacter crescentus and other bacterial species devoid of umuDC. In this work, we have constructed operator-constitutive mutants of the imuABC operon. We used this genetic tool to investigate the effect of SOS-induced levels of these genes upon both spontaneous and damage-induced mutagenesis. We showed that constitutive expression of imuABC does not increase spontaneous or damage-induced mutagenesis, nor increases cellular resistance to DNA-damaging agents. Nevertheless, the presence of the operator-constitutive mutation rescues mutagenesis in a recA background, indicating that imuABC are the only genes required at SOS-induced levels for translesion synthesis (TLS) in C. crescentus. Furthermore, these data also show that TLS mediated by ImuABC does not require RecA, unlike umuDC-dependent mutagenesis in E. coli. Copyright © 2017 Elsevier B.V. All rights reserved.

Lipid dependence of ABC transporter localization and function

NARCIS (Netherlands)

Klappe, Karin; Hummel, Ina; Hoekstra, Dick; Kok, Jan Willem

2009-01-01

Lipid rafts have been implicated in many cellular functions, including protein and lipid transport and signal transduction. ATP-binding cassette (ABC) transporters have also been localized in these membrane domains. In this review the evidence for this specific localization will be evaluated and

ABC transporters of the wheat pathogen Mycosphaerella graminicola

NARCIS (Netherlands)

Zwiers, L.H.

2002-01-01

A TP- b inding c assette (ABC) transporters belong to one of the largest protein families known. They play a role in numerous vital processes in the cell and are characterised by their

Ensemble inequivalence: Landau theory and the ABC model

International Nuclear Information System (INIS)

Cohen, O; Mukamel, D

2012-01-01

It is well known that systems with long-range interactions may exhibit different phase diagrams when studied within two different ensembles. In many of the previously studied examples of ensemble inequivalence, the phase diagrams differ only when the transition in one of the ensembles is first order. By contrast, in a recent study of a generalized ABC model, the canonical and grand-canonical ensembles of the model were shown to differ even when they both exhibit a continuous transition. Here we show that the order of the transition where ensemble inequivalence may occur is related to the symmetry properties of the order parameter associated with the transition. This is done by analyzing the Landau expansion of a generic model with long-range interactions. The conclusions drawn from the generic analysis are demonstrated for the ABC model by explicit calculation of its Landau expansion. (paper)

Ecrire à la suite de : Andrée Lacelle, Andrée Christensen et Jacques Flamand, Paul Savoie et Dyane Léger

Directory of Open Access Journals (Sweden)

Catherine Parayre

2012-05-01

Full Text Available « Ecrire à la suite de » est un procédé d’écriture courant dans la littérature, qu’il s’agisse de mettre en relief l’intertextualité de l’œuvre (par exemple, en incluant des citations, de s’adonner à un travail basé sur l’intermédialité (par exemple, dans un texte rédigé à partir de photographies ou encore d’écrire à quatre mains, lorsqu’un des deux auteurs ajoute son texte à celui du partenaire d’écriture. Ne faisant pas exception, les littératures francophones du Canada pratiquent tout aussi fréquemment cette écriture de l’après. Le présent article en examinera quelques exemples dans des œuvres de nature introspective : La lumière et l’heure : poèmes et carnets (2004 d’Andrée Lacelle, avec des tableaux de Réjine Halimi ; Lithochronos ou le premier vol de la pierre (1999 d’Andrée Christensen et Jacques Flamand, avec des photographies de Christensen ; et L’incendiaire (2008 de Paul Savoie et Dyane Léger. L’analyse montrera que l’écriture « à la suite de », aussi variées qu’en soient les manifestations, non seulement met en évidence la présence de l’auteur dans ces textes, mais a aussi pour résultat, dans ces œuvres méditatives, de dédramatiser et d’amenuiser l’intensité de la réflexion existentielle.

Una mirada al 23 F. Los editoriales de El País y ABC

Directory of Open Access Journals (Sweden)

Aitor Pérez Blázquez

2013-10-01

Full Text Available En el presente artículo pretendemos realizar un acercamiento a uno de los hechos más graves de la democracía española. Nos referimos al fallido intento de golpe de estado del 23 de Febrero. Nos hemos fijado en las líneas editoriales de dos periodicos, ABC y EL Pais, para observar como percibieron y se posicionaron durante los días claves tras el golpe militar.Palabras clave: 23F; Editoriales; El País; ABC 23F, editorials, El País, ABC_________________A look to 23 F. The editorials of El País and ABCAbstract:In the present paper we try to realize an approximation to one of the most serious facts of the Spanish democracy. We refer to 23 F. We have concentrated on the publishing lines of two newspapers, ABC and El País, to observe since they perceived and were positioned during the key days after the militar strike.Keywords:

The Santos Basin Ocean Observing System: From R&D to Operational Regional Forecasts

Science.gov (United States)

Da Rocha Fragoso, M.; Moore, A. M.; dos Santos, F. A.; Marques Da Cruz, L.; Carvalho, G. V.; Soares, F.

2016-02-01

Santos Basin is located on the Southwestern Brazilian Ocean Basin and comprises the main offshore oil reserves of Brazil. The exploration and production activities on its ocean are growing in accelerated pace, which means that oil spill contingency and search & rescue operations are likely to be more frequent. Therefore, ocean current reliable nowcasts and forecasts has become even more important for this region. The Santos Basin Ocean Observing System was designed as an R&D project and its main objective was to establish and maintain a systematic oceanographic data collection for this region in order to study its ocean dynamics and improve regional ocean forecast through data assimilation. In the first three years of the project surface drifters, profiling floats and gliders were deployed to measure and monitor mainly the Brazil Current Western Boundary System, a highly unstable baroclinic current system, that present several meanders and mesoscale eddies activities. Throughout the development of the project, the team involved was able to learn how to operate the equipment, treat the collected data and use it to assimilate on the Regional Ocean Modeling System (ROMS). After performing a one-year 4DVAR assimilation cycle (Fragoso et al., 2015) in which the forecasting skill was assessed, the system was considered mature enough to start producing ocean circulation forecasts for Santos Basin. It is the first time in Brazil that a regional ocean model using a 4DVAR data assimilation scheme was used to produce high resolution operational ocean current forecasts. This paper describes all the components of this forecasting system, its main results and discoveries with special focus on the Brazil Current System Transport and mesocale eddies dynamics and statistics.

Polycyclic aromatic hydrocarbons (PAHs) in a large South American industrial coastal area (Santos Estuary, Southeastern Brazil): Sources and depositional history

International Nuclear Information System (INIS)

Martins, Cesar C.; Bicego, Marcia C.; Mahiques, Michel M.; Figueira, Rubens C.L.; Tessler, Moyses G.; Montone, Rosalinda C.

2011-01-01

Highlights: → In early 1980s, Santos Estuary became known as one of the worst polluted in the world. → PAHs levels were similar to the values reported for marine sediments worldwide. → PAHs analyses indicated multiple sources of these compounds (oil and pyrolitic origin). → The decline of oil consumption due to the world oil crisis (late 1970s) was shown. → The input of organic pollutants is a historical problem for the Santos Estuary. - Abstract: Located in southeastern Brazil, the Santos Estuary has the most important industrial and urban population area of South America. Since the 1950's, increased urbanization and industrialization near the estuary margins has caused the degradation of mangroves and has increased the discharge of sewage and industrial effluents. The main objectives of this work were to determine the concentrations and sources of polycyclic aromatic hydrocarbons (PAHs) in sediment cores in order to investigate the input of these substances in the last 50 years. The PAHs analyses indicated multiple sources of these compounds (oil and pyrolitic origin), basically anthropogenic contributions from biomass, coal and fossil fuels combustion. The distribution of PAHs in the cores was associated with the formation and development of Cubatao industrial complex and the Santos harbour, waste disposal, world oil crisis and the pollution control program, which results in the decrease of organic pollutants input in this area.

André Gide, Gide & Amrouche. Correspondance (1928-1950)

OpenAIRE

Amadessi, Veronica

2016-01-01

En 1928, le jeune Jean el-Mouhoub Amrouche captive l’attention d’André Gide dans une lettre qu’il lui adresse personnellement. À cette époque, la réputation de l’auteur de L’Immoraliste ne cesse de grandir, alors que l’expéditeur n’est qu’un «brillant» normalien inconnu au grand public. Il s’agit toutefois d’un jeune kabyle aux idées bien précises, qui exprime, dans cette première missive, sa volonté de se faire le porte-parole de l’identité kabyle tout en préservant son amour pour la France....

ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal

Directory of Open Access Journals (Sweden)

Choi Cheol-Hee

2005-10-01

Full Text Available Abstract One of the major problems related with anticancer chemotherapy is resistance against anticancer drugs. The ATP-binding cassette (ABC transporters are a family of transporter proteins that are responsible for drug resistance and a low bioavailability of drugs by pumping a variety of drugs out cells at the expense of ATP hydrolysis. One strategy for reversal of the resistance of tumor cells expressing ABC transporters is combined use of anticancer drugs with chemosensitizers. In this review, the physiological functions and structures of ABC transporters, and the development of chemosensitizers are described focusing on well-known proteins including P-glycoprotein, multidrug resistance associated protein, and breast cancer resistance protein.

Hepatectomia para o tratamento de metástases colorretais e não-colorretais: análise comparativa em 30 casos operados Hepatectomy for metastasis from colorectal and non-colorectal origin: comparative analysis in 30 resectable cases

Directory of Open Access Journals (Sweden)

Sergio Renato Pais Costa

2009-06-01

Full Text Available RACIONAL: Hepatectomia é a melhor opção terapêutica curativa para metástases hepáticas de origem colorretal. Mais recentemente, ressecção hepática também tem sido realizada para metástases de etiologia não-colorretal. OBJETIVO: Comparar os resultados em curto e longo prazo de uma série de hepatectomias para 20 doentes com metástase colorretal com uma série de 10 doentes com metástase não-colorretal realizadas pelo Serviço de Cirurgia Geral (Disciplina de Cirurgia do Aparelho Digestivo da Faculdade Medicina do ABC (Santo André - Brasil. MÉTODOS: Os dados completos de 30 doentes submetidos à hepatectomia por metástase metacrônica entre o período de Janeiro de 2001 e Setembro de 2007 foram avaliados. Vinte com metástase colorretal (Grupo 1 foram comparados com dez com metástase não-colorretal (Grupo 2. Foi realizada análise multivariada dos fatores prognósticos com o programa Epi-Info para Windows. RESULTADOS: Foram realizadas vinte hepatectomias maiores e dez hepatectomias menores. A morbidade foi similar entre os grupos (p >0,05. A mortalidade cirúrgica foi maior no Grupo 1 do que no Grupo 2 (5 % X 0 %, mas não houve significância estatística (p>0,05. Os índices de sobrevida global em 3 e 5 anos foram comparáveis entre os dois grupos (p>0,05. CONCLUSÃO: Nessa amostra, a ressecção hepática para metástase de etiologia não-colorretal apresenta resultados similares aos da metástase colorretal com sobrevida em cinco anos de 20 %. Foram fatores prognósticos adversos: mais que uma metástase e linfonodo positivo.BACKGROUND: Hepatectomy has presented the best curative therapeutic choice for hepatic metastatic colorectal cancer. More recently, hepatic resection has been performed for hepatic metastases from non-colorectal origin too. AIM: To compare both early and long-term surgical outcomes on 20 patients' series of colorectal with 10 patients' series of non-colorectal hepatic metastases realized by General

Knock-down of ABCE1 gene induces G1/S arrest in human oral cancer cells

OpenAIRE

Wang, Lei; Zhang, Mei; Liu, Dong-Xu

2014-01-01

Purpose: This study aims to explore the clinical characteristics of ATP binding cassette E1 (ABCE1) in oral squamous cell carcinomas (OSCC) and its roles in the proliferation, invasiveness, migration and apoptosis of the human oral squamous cell carcinoma cells CAL-27. Methods: The expression of ABCE1 and its target protein-RNase L, were first studied in tumor tissues of OSCC and adjacent non-tumor tissues. Moreover, CAL-27cells were transfected by ABCE1-specific shRNA, then MTT assay, the tr...

Tõnu Anton kahtlustab linnaisasid omakasu jahtimises / Tõnu Anton, Andres Kõiv, Ando Hagel ; interv. Ulis Guth

Index Scriptorium Estoniae

Anton, Tõnu, 1942-

2004-01-01

Võru linnavolikogu opositsiooni kuuluv keskerakondlane Tõnu Anton kritiseerib sotsiaalabitalituse ruumide remondirahade kasutamist ja kahtlustab linnavalitsust riigihangete käigus raha kõrvaldamises. Linnapea Ando Hagel ja abilinnapea Andres Kõiv lükkavad süüdistused tagasi

ABC transporters from Aspergillus nidulans are involved in protection against cytotoxic agents and antibiotic production

NARCIS (Netherlands)

Andrade, A.C.; Nistelrooy, van J.G.M.; Peery, R.B.; Skatrud, P.L.; Waard, de M.A.

2000-01-01

This paper describes the characterization of atrC and atrD (ABC transporters C and D), two novel ABC transporter-encoding genes from the filamentous fungus Aspergillus nidulans, and provides evidence for the involvement of atrD in multidrug transport and antibiotic production. BLAST analysis of the

Classification of E-Nose Aroma Data of Four Fruit Types by ABC-Based Neural Network

Directory of Open Access Journals (Sweden)

M. Fatih Adak

2016-02-01

Full Text Available Electronic nose technology is used in many areas, and frequently in the beverage industry for classification and quality-control purposes. In this study, four different aroma data (strawberry, lemon, cherry, and melon were obtained using a MOSES II electronic nose for the purpose of fruit classification. To improve the performance of the classification, the training phase of the neural network with two hidden layers was optimized using artificial bee colony algorithm (ABC, which is known to be successful in exploration. Test data were given to two different neural networks, each of which were trained separately with backpropagation (BP and ABC, and average test performances were measured as 60% for the artificial neural network trained with BP and 76.39% for the artificial neural network trained with ABC. Training and test phases were repeated 30 times to obtain these average performance measurements. This level of performance shows that the artificial neural network trained with ABC is successful in classifying aroma data.

Classification of E-Nose Aroma Data of Four Fruit Types by ABC-Based Neural Network.

Science.gov (United States)

Adak, M Fatih; Yumusak, Nejat

2016-02-27

Electronic nose technology is used in many areas, and frequently in the beverage industry for classification and quality-control purposes. In this study, four different aroma data (strawberry, lemon, cherry, and melon) were obtained using a MOSES II electronic nose for the purpose of fruit classification. To improve the performance of the classification, the training phase of the neural network with two hidden layers was optimized using artificial bee colony algorithm (ABC), which is known to be successful in exploration. Test data were given to two different neural networks, each of which were trained separately with backpropagation (BP) and ABC, and average test performances were measured as 60% for the artificial neural network trained with BP and 76.39% for the artificial neural network trained with ABC. Training and test phases were repeated 30 times to obtain these average performance measurements. This level of performance shows that the artificial neural network trained with ABC is successful in classifying aroma data.

Genome-wide analysis of the ATP-binding cassette (ABC) transporter gene family in sea lamprey and Japanese lamprey.

Science.gov (United States)

Ren, Jianfeng; Chung-Davidson, Yu-Wen; Yeh, Chu-Yin; Scott, Camille; Brown, Titus; Li, Weiming

2015-06-06

Lampreys are extant representatives of the jawless vertebrate lineage that diverged from jawed vertebrates around 500 million years ago. Lamprey genomes contain information crucial for understanding the evolution of gene families in vertebrates. The ATP-binding cassette (ABC) gene family is found from prokaryotes to eukaryotes. The recent availability of two lamprey draft genomes from sea lamprey Petromyzon marinus and Japanese lamprey Lethenteron japonicum presents an opportunity to infer early evolutionary events of ABC genes in vertebrates. We conducted a genome-wide survey of the ABC gene family in two lamprey draft genomes. A total of 37 ABC transporters were identified and classified into seven subfamilies; namely seven ABCA genes, 10 ABCB genes, 10 ABCC genes, three ABCD genes, one ABCE gene, three ABCF genes, and three ABCG genes. The ABCA subfamily has expanded from three genes in sea squirts, seven and nine in lampreys and zebrafish, to 13 and 16 in human and mouse. Conversely, the multiple copies of ABCB1-, ABCG1-, and ABCG2-like genes found in sea squirts have contracted in the other species examined. ABCB2 and ABCB3 seem to be new additions in gnathostomes (not in sea squirts or lampreys), which coincides with the emergence of the gnathostome-specific adaptive immune system. All the genes in the ABCD, ABCE and ABCF subfamilies were conserved and had undergone limited duplication and loss events. In the sea lamprey transcriptomes, the ABCE and ABCF gene subfamilies were ubiquitously and highly expressed in all tissues while the members in other gene subfamilies were differentially expressed. Thirteen more lamprey ABC transporter genes were identified in this study compared with a previous study. By concatenating the same gene sequences from the two lampreys, more full length sequences were obtained, which significantly improved both the assignment of gene names and the phylogenetic trees compared with a previous analysis using partial sequences. The ABC

Accuracy of shock index versus ABC score to predict need for massive transfusion in trauma patients.

Science.gov (United States)

Schroll, Rebecca; Swift, David; Tatum, Danielle; Couch, Stuart; Heaney, Jiselle B; Llado-Farrulla, Monica; Zucker, Shana; Gill, Frances; Brown, Griffin; Buffin, Nicholas; Duchesne, Juan

2018-01-01

Various scoring systems have been developed to predict need for massive transfusion in traumatically injured patients. Assessments of Blood Consumption (ABC) score and Shock Index (SI) have been shown to be reliable predictors for Massive Transfusion Protocol (MTP) activation. However, no study has directly compared these two scoring systems to determine which is a better predictor for MTP activation. The primary objective was to determine whether ABC or SI better predicted the need for MTP in adult trauma patients with severe hemorrhage. This was a retrospective cohort study which included all injured patients who were trauma activations between January 1, 2009 and December 31, 2013 at an urban Level I trauma center. Patients ABC and SI were calculated for each patient. MTP was defined as need for >10 units PRBC transfusion within 24h of emergency department arrival. Sensitivity, specificity, and area under the receiver operating characteristic curve (AUROC) were used to evaluate scoring systems' ability to predict effective MTP utilization. A total of 645 patients had complete data for analysis. Shock Index ≥1 had sensitivity of 67.7% (95% CI 49.5%-82.6%) and specificity of 81.3% (95% CI 78.0%-84.3%) for predicting MTP, and ABC score ≥2 had sensitivity of 47.0% (95% CI 29.8%-64.9%) and specificity of 89.8% (95% CI 87.2%-92.1%). AUROC analyses showed SI to be the strongest predictor followed by ABC score with AUROC values of 0.83 and 0.74, respectively. SI had a significantly greater sensitivity (P=0.035), but a significantly weaker specificity (PABC score. ABC score and Shock Index can both be used to predict need for massive transfusion in trauma patients, however SI is more sensitive and requires less technical skill than ABC score. Copyright © 2017 Elsevier Ltd. All rights reserved.

The natural population of bees of the earth (Melipona beecheii) and their flora in the valley San Andrés

OpenAIRE

Katiuska Ravelo Pimentel; Fernando Ramón Hernández Martínez; Iván Paneque Torres; Luisa Elena Toledo Peña; Hilda Gutiérrez Hernández

2014-01-01

The relationship of the natural population of bees of the earth is evaluated (Melipona beecheii) and its flora in the valley San Andrés, to inclination observations and samplings carried out in the formations studied vegetable. The melliferous plants and their use like tree of the nest of Melipona beecheii were studied for each one of the vegetable formations of the valley San Andrés, the indexes of diversity and their relationship were also analyzed with the values of density of colonies. It...

Risk factors associated with multidrug-resistant tuberculosis in Espírito Santo, Brazil.

Science.gov (United States)

Fregona, Geisa; Cosme, Lorrayne Belique; Moreira, Cláudia Maria Marques; Bussular, José Luis; Dettoni, Valdério do Valle; Dalcolmo, Margareth Pretti; Zandonade, Eliana; Maciel, Ethel Leonor Noia

2017-04-27

To analyze the prevalence and factors associated with multidrug-resistant tuberculosis in Espírito Santo, Brazil. This is a cross-sectional study of cases of tuberculosis tested for first-line drugs (isoniazid, rifampicin, pyrazinamide, ethambutol, and streptomycin) in Espírito Santo between 2002 and 2012. We have used laboratory data and registration of cases of tuberculosis - from the Sistema Nacional de Agravos de Notificação and Sistema para Tratamentos Especiais de Tuberculose. Individuals have been classified as resistant and non-resistant and compared in relation to the sociodemographic, clinical, and epidemiological variables. Some variables have been included in a logistic regression model to establish the factors associated with resistance. In the study period, 1,669 individuals underwent anti-tuberculosis drug susceptibility testing. Of these individuals, 10.6% showed resistance to any anti-tuberculosis drug. The rate of multidrug resistance observed, that is, to rifampicin and isoniazid, has been 5%. After multiple analysis, we have identified as independent factors associated with resistant tuberculosis: history of previous treatment of tuberculosis [recurrence (OR = 7.72; 95%CI 4.24-14.05) and re-entry after abandonment (OR = 3.91; 95%CI 1.81-8.43)], smoking (OR = 3.93; 95%CI 1.98-7.79), and positive culture for Mycobacterium tuberculosis at the time of notification of the case (OR = 3.22; 95%CI 1.15-8.99). The partnership between tuberculosis control programs and health teams working in the network of Primary Health Care needs to be strengthened. This would allow the identification and monitoring of individuals with a history of previous treatment of tuberculosis and smoking. Moreover, the expansion of the offer of the culture of tuberculosis and anti-tuberculosis drug susceptibility testing would provide greater diagnostic capacity for the resistant types in Espírito Santo. Analisar a prevalência e fatores associados à tuberculose resistente

ANALISIS BEBAN KERJA DENGAN MENGGUNAKAN METODE CVL DAN NASATLX DI PT. ABC

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Renty Anugerah Mahaji Puteri

2017-10-01

Full Text Available PT. ABC merupakan perusahaan Jepang yang bergerak di bidang usaha jasa konstruksi mekanikal, elektrikal, dan system komunikasi. Sebagai perusahaan jasa konstruksi, PT. ABC dituntut untuk mencapai tujuan / target perusahaan tiap tahunnya yaitu mendapatkan tender proyek, maka tak jarang karyawannya dituntut untuk lembur. Seringnya karyawan lembur, maka menimbulkan masalah kelelahan terhadap para karyawannya sehingga target tidak tercapai. Penelitian ini bertujuan untuk mengevaluasi beban kerja yang dialami oleh engineer leader pada Departemen DesaindanOperasional di PT. ABC. Beban kerja yang diukur adalah beban kerja fisik dan mental. Beban kerja fisik diukur berdasarkan cardiovascular load (CVL. Beban kerja mental diukur dengan menggunakan metode NASA-Task Load Index (NASA-TLX. Berdasarkan hasil analisis CVL, beban kerja fisik yang diterima engineer proyek memiliki presentase CVL sebesar 31,16%, denganhasilperbaikanmenjadi 23,38%. Sedangkan dari hasil analisis NASA-TLX, beban kerja mental yang diterima engineer proyek yaitu dengan skor NASA-TLX 74,2% denganhasilperbaikanmenjadi 51,6%, sedangkan skor NASA-TLX engineer head office 61,5% denganhasilperbaikanmenjadi 47,66%.

The short version of the Activities-specific Balance Confidence (ABC) scale: Its validity, reliability, and relationship to balance impairment and falls in older adults

OpenAIRE

Schepens, Stacey; Goldberg, Allon; Wallace, Melissa

2009-01-01

A shortened version of the ABC 16-item scale (ABC-16), the ABC-6, has been proposed as an alternative balance confidence measure. We investigated whether the ABC-6 is a valid and reliable measure of balance confidence and examined its relationship to balance impairment and falls in older adults. Thirty-five community-dwelling older adults completed the ABC-16, including the six questions of the ABC-6. They also completed the following clinical balance tests: unipedal stance time (UST), functi...

The A-B-C of recycling

DEFF Research Database (Denmark)

Thøgersen, John; Ølander, Carl Folke

specifically the source separation of compostable kitchen waste. The investigation was carried out before and after the introduction of a system, facilitating such separation, in a Danish community. Hypotheses derived from the A-B-C model, predicting that changes over time in the correlation between attitude...... and behaviour would be influenced by (a) the introduction of the system, and (b) the pre-intervention structural conditions for different groups of households, were supported....

Purification and biochemical characterisation of the yeast ABC transporter Pdr11p

DEFF Research Database (Denmark)

Laub, Katrine Rude

Sterols constitute an essential lipid class in eukaryotic membranes where intracellular distributions are highly regulated. In the yeast Saccharomyces cerevisiae sterol uptake has been attributed to the two plasma membrane-localised ATP-binding cassette (ABC) transporters, Aus1p and Pdr11p...... of the yeast ABC transporter Pdr11p. This includes optimising its overexpression utilising the galactose induction system in S. cerevisiae, screening for the best detergent to extract the protein from the membrane, and establishing purification and reconstitution protocols. By providing a purification...

Retrospective analysis of concurrent chemoradiotherapy for head and neck squamous-cell carcinoma: preliminary experience from ABC School of Medicine, Santo Andre, Sao Paulo State, Brazil

International Nuclear Information System (INIS)

Borba Junior, Antonio Freitas; Giglio, Auro del; Philbert, Paula Lajolo; Kaliks, Rafael

2005-01-01

Background: concurrent chemoradiotherapy constitutes an option for head and neck squamous-cell carcinoma (HNSCC) treatment. Although we found a high incidence of this tumor in our population, we do not have so far results reported for the Brazilian population. Methods: medical records from HNSCC patients who ere treated with concurrent chemoradiotherapy between January 2001 to June 2004 were systematically reviewed. Results: twenty-two HNSCC patients were treated with chemoradiotherapy. The median age was 56 years. The primary tumor site was located in the oropharynx in 11, the larynx in 9 and hypopharynx in 2 patients. Most of the patients (86%) presented with stage III or IV disease. 19 (86%) patients were treated with Cisplatin 100 mg/m 2 D1-22-43, and 3 (14%) patients used Cisplatin 20 mg/m 2 weekly, concurrent with radiotherapy. Hematological and renal toxicity grade 3 or higher was seen in 58% and 10% patients, respectively. Eleven patients achieved a complete response and 8 a partial response. Median disease-free survival was 10 months and median overall survival was 25 months. (author)

Who Is DeAndre? Tapping the Power of Popular Culture in Literacy Learning

Science.gov (United States)

Gainer, Jesse

2008-01-01

Gainer talks about the importance of connecting students' background knowledge, experiences, and interests to curricular goals. He highlights the voice of DeAndre, an eighth-grade boy in special education classes, whose participation in an after-school club led to the creation of a video. According to Gainer, "[W]hen given the opportunity to…

Religiosidad en Al-Andalus: el hombre santo en el Islam occidental

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Rodríguez Mediano, Fernando

1999-06-01

Full Text Available Hagiographical literature in Western Islam is abundant from the 12th-13th centuries onward, and is tied to the introduction and expansión of sufism in al-Andalus and Morocco. In this paper I analyse three hagiographical texts from al-Andalus in order to understand how the authority of a holy man is constructed from two perspectives: fear of his miraculous power and love inspired in his followers. Through these two passions, love and fear, one can infer the existence of a political and religious pattern for authoritarian relationships in Western Islam.Los siglos XII y XIII son fundamentales para la expansión del sufismo en el Occidente musulmán y para la creación de una tradición hagiográfica puramente magrebí. En este artículo se utilizan tres textos hagiográficos andalusíes de esa época para analizar cómo se construye la autoridad del hombre santo desde una doble perspectiva: la del miedo a la acción del santo y la del amor que inspira. A través de estas pasiones se puede rastrear la existencia de un modelo de autoridad que es a la vez religioso y político.

Mortality from liver cirrhosis in Espírito Santo State, Brazil

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Patricia Lofego Gonçalves

2014-06-01

Full Text Available To study mortality from liver cirrhosis in Espírito Santo State, Brazil, we reviewed death certificates (DC from 2000-2010 and medical records of deceased patients with investigation of alcoholism and hepatitis B or C. From a total of 218,410 DC, 3,554 deaths from liver cirrhosis were retrieved. The annual mortality rate was 19.8/100,000 for men and 4.31/100,000 for women, without significant changes after correction for ICD-R98 and R99 and without a significant increase in the annual percentage change. In 49% of death certificates, the aetiology of cirrhosis was defined: of these alcoholism in 81.5% of cases and viral hepatitis in 15.7%. Aetiology was confirmed in 262 reviewed records, including alcoholism (40.5%; hepatitis B or C (26.7%; other (3.8%; and cryptogenic (10.6%. The mean annual potential years of life lost were 5,946 years and 1,739 years for men and women respectively. The mortality rate from cirrhosis in Espírito Santo State is intermediate in relationship to worldwide data; alcoholism and hepatitis B or C were the main aetiologies; probably alcoholism is overestimated and hepatitis B and C viruses are underestimated as causes of cirrhosis registered on death certificates.

Indústria, ordenamento do território e transportes – a contribuição de André Fischer

Directory of Open Access Journals (Sweden)

Áurea Breitbach

2009-03-01

Full Text Available Indústria, ordenamento do território e transportes – a contribuição de André Fischer, Organização Olga Lúcia C. Firkowski e Eliseu S. Sposito, Editora Expressão Popular, 2008, 160 p.Este livro é uma iniciativa conjunta dos Programas de Pós-Graduação em Geografia da Universidade Federal do Paraná e da Universidade Estadual Paulista/Presidente Prudente. Conforme os organizadores, a intenção foi publicar um livro que homenageasse André Fischer e, para tanto, foram reunidos diversos textos escrit...

Distribution of Th-232 and Th-228 in Santos and Sao Vicente Estuary, Sao Paulo, Brazil

Energy Technology Data Exchange (ETDEWEB)

Silva, P.S.C.; Mazzilli, B.P.; Favaro, D.I.T. [Instituto de Pesquisas Energeticas e Nucleares, Av. Lineu Prestes, 2242, Caixa Postal 05508-000, Cidade Universitaria, Sao Paulo (Brazil)]. e-mail: Pscsilva@ipen.br

2004-07-01

In the last decades considerable attention has been given to technologically enhanced natural occurring radioactive material (TENORM). Within this frame, of particular concern is the phosphate fertilizer industry. Santos Basin, located in Southwest Brazil, Sao Paulo State, comprising Santos and Sao Vicente estuarine system, is considered the most important industrial region of the country. Among the industrial activities present, phosphate fertilizer plants are responsible for the production of 69 millions tons of phosphogypsum waste, which is stockpiled in the surrounding environment. This waste concentrates radionuclides of the natural series originally present in the phosphate rock used as raw material. This study aims to evaluate the environmental impact of such activities in the sediments of the estuarine system. {sup 232} Th and {sup 228} Th concentrations in Santos and San Vicente estuary sediments were determined by Neutron activation analysis and Gamma spectrometry, respectively. {sup 232} Th concentration ranged from 6.5 to 198 Bq kg{sup -1} with mean value of 57 {+-} 39 Bq kg{sup -1}, for 42 samples. {sup 228} Th content varied from 12 to 110 Bq kg{sup -1} with a mean value of 74 {+-} 23 Bq kg{sup -1}, for 18 samples. It can be seen that the amount of {sup 232} Th is higher in the rivers close to the phosphogypsum piles, at least five points were identified as being affected by anthropogenic factor. (Author)

Distribution of Th-232 and Th-228 in Santos and Sao Vicente Estuary, Sao Paulo, Brazil

International Nuclear Information System (INIS)

Silva, P.S.C.; Mazzilli, B.P.; Favaro, D.I.T.

2004-01-01

In the last decades considerable attention has been given to technologically enhanced natural occurring radioactive material (TENORM). Within this frame, of particular concern is the phosphate fertilizer industry. Santos Basin, located in Southwest Brazil, Sao Paulo State, comprising Santos and Sao Vicente estuarine system, is considered the most important industrial region of the country. Among the industrial activities present, phosphate fertilizer plants are responsible for the production of 69 millions tons of phosphogypsum waste, which is stockpiled in the surrounding environment. This waste concentrates radionuclides of the natural series originally present in the phosphate rock used as raw material. This study aims to evaluate the environmental impact of such activities in the sediments of the estuarine system. 232 Th and 228 Th concentrations in Santos and San Vicente estuary sediments were determined by Neutron activation analysis and Gamma spectrometry, respectively. 232 Th concentration ranged from 6.5 to 198 Bq kg -1 with mean value of 57 ± 39 Bq kg -1 , for 42 samples. 228 Th content varied from 12 to 110 Bq kg -1 with a mean value of 74 ± 23 Bq kg -1 , for 18 samples. It can be seen that the amount of 232 Th is higher in the rivers close to the phosphogypsum piles, at least five points were identified as being affected by anthropogenic factor. (Author)

Metal and trace element assessment of estuary sediments from Santos, Brazil, by neutron activation and atomic absorption techniques

International Nuclear Information System (INIS)

Amorim, Eduardo P.; Favaro, Deborah I.T.; Berbel, Glaucia B.B.; Braga, Elisabete S.

2007-01-01

In order to better understanding geochemical and environmental processes and their possible changes due to anthropogenic activities trace metal analyses and their distribution in marine sediments are commonly undertaken. The present study reports result concerning the distribution of some major, trace and rare earth elements in the Santos estuarine marine sediments. Thirteen bottom sediment samples (SV0501 to SV0513) were collected in this estuary, including regions of Sao Vicente, Santos, Cubatao, Vicente de Carvalho and Santos' Bay, in the summer of 2005. Multielemental analysis was carried out by instrumental neutron activation analysis (INAA). For total mercury determination cold vapor atomic absorption technique (CV AAS) was employed. In both cases methodology validation was performed by certified reference material analyses. The results obtained for multielemental concentrations in the sediment samples were compared with NASC (North American Shale Composite) values. The concentration values obtained for As and metals Cr, Hg and Zn in the sediment samples were compared to Canadian Council of Minister of the Environment (CCME) oriented values (TEL and PEL values). In general, the samples located near the Cubatao region showed higher concentrations for all elements analyzed probably due to the high impact of industrial activities. (author)

Metal and trace element assessment of estuary sediments from Santos, Brazil, by neutron activation and atomic absorption techniques

Energy Technology Data Exchange (ETDEWEB)

Amorim, Eduardo P.; Favaro, Deborah I.T. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)]. E-mails: ducamorim@yahoo.com.br; defavaro@ipen.br; Berbel, Glaucia B.B.; Braga, Elisabete S. [Universidade de Sao Paulo (USP), SP (Brazil). Inst. Oceanografico. Lab. de Nutrientes, Micronutrientes e Tracos nos Oceanos - LABNUT]. E-mail: edsbraga@usp.br

2007-07-01

In order to better understanding geochemical and environmental processes and their possible changes due to anthropogenic activities trace metal analyses and their distribution in marine sediments are commonly undertaken. The present study reports result concerning the distribution of some major, trace and rare earth elements in the Santos estuarine marine sediments. Thirteen bottom sediment samples (SV0501 to SV0513) were collected in this estuary, including regions of Sao Vicente, Santos, Cubatao, Vicente de Carvalho and Santos' Bay, in the summer of 2005. Multielemental analysis was carried out by instrumental neutron activation analysis (INAA). For total mercury determination cold vapor atomic absorption technique (CV AAS) was employed. In both cases methodology validation was performed by certified reference material analyses. The results obtained for multielemental concentrations in the sediment samples were compared with NASC (North American Shale Composite) values. The concentration values obtained for As and metals Cr, Hg and Zn in the sediment samples were compared to Canadian Council of Minister of the Environment (CCME) oriented values (TEL and PEL values). In general, the samples located near the Cubatao region showed higher concentrations for all elements analyzed probably due to the high impact of industrial activities. (author)

Integrated quality assessment of sediments from harbour areas in Santos-São Vicente Estuarine System, Southern Brazil

Science.gov (United States)

Buruaem, Lucas Moreira; de Castro, Ítalo Braga; Hortellani, Marcos Antonio; Taniguchi, Satie; Fillmann, Gilberto; Sasaki, Silvio Tarou; Varella Petti, Mônica Angélica; Sarkis, Jorge Eduardo de Souza; Bícego, Márcia Caruso; Maranho, Luciane Alves; Davanso, Marcela Bergo; Nonato, Edmundo Ferraz; Cesar, Augusto; Costa-Lotufo, Leticia Veras; Abessa, Denis Moledo de Souza

2013-09-01

Santos-São Vicente Estuarine System is a highly populated coastal zone in Brazil and where it is located the major port of Latin America. Historically, port activities, industrial and domestic effluents discharges have constituted the main sources of contaminants to estuarine system. This study aimed to assess the recent status of sediment quality from 5 zones of Port of Santos by applying a lines-of-evidence approach through integrating results of: (1) acute toxicity of whole sediment and chronic toxicity of liquid phases; (2) grain size, organic matter, organic carbon, nitrogen, phosphorus, trace metals, polycyclic aromatic hydrocarbons, linear alkylbenzenes and butyltins; (3) benthic community descriptors. Results revealed a gradient of increasing contamination for metals and organic compounds, alongside with their geochemical carriers. Sediment liquid phases were more toxic compared to whole sediment. Low number of species and individuals indicated the impoverishment of benthic community. The use of site-specific sediment quality guidelines was more appropriate to predict sediment toxicity. The integration of results through Sediment Quality Triad approach and principal component analysis allowed observing the effects of natural stressors and dredging on sediment quality and benthic distribution. Even with recent governmental efforts to control, pollution is still relevant in Port of Santos and a threat to local ecosystems.

Differential contributions of five ABC transporters to mutidrug resistance, antioxidion and virulence of Beauveria bassiana, an entomopathogenic fungus.

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Ting-Ting Song

Full Text Available Multidrug resistance (MDR confers agrochemical compatibility to fungal cells-based mycoinsecticdes but mechanisms involved in MDR remain poorly understood for entomopathogenic fungi, which have been widely applied as biocontrol agents against arthropod pests. Here we characterized the functions of five ATP-binding cassette (ABC transporters, which were classified to the subfamilies ABC-B (Mdr1, ABC-C (Mrp1 and ABC-G (Pdr1, Pdr2 and Pdr5 and selected from 54 full-size ABC proteins of Beauveria bassiana based on their main domain architecture, membrane topology and transcriptional responses to three antifungal inducers. Disruption of each transporter gene resulted in significant reduction in resistance to four to six of eight fungicides or antifungal drugs tested due to their differences in structure and function. Compared with wild-type and complemented (control strains, disruption mutants of all the five transporter genes became significantly less tolerant to the oxidants menadione and H₂O₂ based on 22-41% and 10-31% reductions of their effective concentrations required for the suppression of 50% colony growth at 25°C. Under a standardized spray, the killing actions of ΔPdr5 and ΔMrp1 mutants against Spodoptera litura second-instar larvae were delayed by 59% and 33% respectively. However, no significant virulence change was observed in three other delta mutants. Taken together, the examined five ABC transporters contribute differentially to not only the fungal MDR but antioxidant capability, a phenotype rarely associated with ABC efflux pumps in previous reports; at least some of them are required for the full virulence of B. bassiana, thereby affecting the fungal biocontrol potential. Our results indicate that ABC pump-dependent MDR mechanisms exist in entomopathogenic fungi as do in yeasts and human and plant pathogenic fungi.

Carlos Hugo Molina Saucedo. Andrés Ibáñez, un caudillo para el siglo XXI. La Comuna de Santa Cruz de la Sierra de 1876; Andrey Schelchkov. Andrés Ibáñez y la Revolución de la Igualdad en Santa Cruz: primer ensayo de federalismo en Bolivia, 1876-1877

Directory of Open Access Journals (Sweden)

Clayton Mendonça Cunha Filho

2014-11-01

Full Text Available Carlos Hugo Molina Saucedo. Andrés Ibáñez, un caudillo para el siglo XXI. La Comuna de Santa Cruz de la Sierra de 1876Andrey Schelchkov. Andrés Ibáñez y la Revolución de la Igualdad en Santa Cruz: primer ensayo de federalismo en Bolivia, 1876-1877

Osabc1k8, an abc1-like kinase gene, mediates abscisic acid sensitivity and dehydration tolerance response in rice seedlings

International Nuclear Information System (INIS)

Liu, Y.; Li, T.; Yang, C.

2015-01-01

The activity of bc1 complex kinase (ABC1K) protein family, which widely exists in prokaryotes and eukaryotes, consists of 15 members in rice, and the role of this family in plants has not yet been studied in details. In this study, a novel function of OsABC1K8 (LOC-Os06g48770), a member of rice ABC1K family, was characterized. The transcript level of OsABC1K8 changes in response to salt, dehydration, cold, PEG, oxidative (H/sub 2/O/sub 2/) stresses, or abscisic acid (ABA) treatment. Overexpression of OsABC1K8 significantly increased sensitivity to dehydration and reduced sensitivity to ABA. In the contrast, RNAi transgenic lines displayed significantly reduced sensitivity to dehydration stress and increased sensitivity to ABA. Furthermore, the transcriptional levels of several ABA/stress-regulated responsive genes were suppressed in OsABC1K8 over-expressing plants under dehydration stress. In conclusion, our results suggested that OsABC1K8 is a negative regulator in response to dehydration stress through an ABA-dependent pathway. (author)

Activity-based Costing (ABC and Activity-based Management(ABMImplementation – Is This the Solution for Organizations to Gain Profitability?

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Ildikó Réka CARDOS

2011-06-01

Full Text Available Adherents of ABC/ABM systems claimed traditional management accounting systems generated misleading costs in a contemporary, tumultuous, often changing business environment and implementing ABC/ABM would remedy this. That is why activity-based costing (ABC and activity-based management (ABM represents the symbol of improved competitiveness and efficiency in every organization.The purpose of this article – after analyzing the existing literature in the field – is to emphasize that new cost systems such as ABC and ABM could be a strong couple that assures competitiveness and efficiency for each company. Another objective is to present that, besides its disadvantages, firms implement the ABC/ABM system because it permits better tracing of costs to objects, superior allocation of overheads to cost objects, financial and non-financial analysis and measures useful to managers and management accountants in the decision-making process.

Archaeometric studies in the Franciscan convent of Santo Antonio - Recife, Pernambuco, Brazil

International Nuclear Information System (INIS)

Azevedo, Renata L.; Asfora, Viviane K.; Ribeiro, Guilherme B.; Ferreira, Joao Victor C.; Khoury, Helen J.; Sullasi, Henry S.L.; Rego, Nuno Jose S.; Mello, Jose Aylton C. de

2011-01-01

The purpose of this paper is to characterize the tiles placed on the walls of the Franciscan convent of Santo Antonio (Recife-PE) and to obtain information about the several expansions and structural reforms performed on the convent by dating the bricks. For this purpose, a portable energy dispersive X-Ray Fluorescence (EDXRF) was used to characterize the tiles. The dating of the bricks was performed using the Thermoluminescence (TL) technique. The results of the EDXRF analysis show that the dominant component of the white pigment is Lead [2PbCO 3 .Pb (OH) 2 ], used since the ancient times until the twentieth century, while the dominant element of the blue pigment is Cobalt (CoO.Al 2 O 3 ), that has been used from 1807 until nowadays. The TL dating of bricks indicate that there were walls with different periods of construction, being one built around 1765, with a deviation of 28 years, whereas other was built later, around 1874, with a deviation of 15 years. These results provide new data towards understanding how and when the Recife Franciscan Convent of Santo Antonio was designed and built, contributing to other research works presently underway on site. (author)

Cultura, identidad política y multiculturalidad en Todos Santos, BCS1

Directory of Open Access Journals (Sweden)

Rossana Almada

2005-01-01

Full Text Available Este ensayo tiene como objetivo hablar del desbordamiento institucional de la política y su desplazamiento hacia la sociedad civil. Desde luego, no es la intención negar la importancia de instituciones políticas tales como partidos, sino señalar cómo la morfología de la complejidad social desdibuja las fronteras de la representación y traslada las demandas a las calles, a las cantinas,a las casas de los interesados. El trabajo forma parte de una investigación mayor a la que he llamado Juntos, pero no revueltos. Multiculturalidad e identidad local en Todos Santos, BCS, es por eso que presento como ejemplo de este fenómeno el caso del conflicto latente en Todos Santos, Baja California Sur (BCS tanto por el uso de los espacios como por las formas que tendrá que adquirir la identidad local que construyen, a partir de sus convergencias y negociaciones, los tres grupos en lucha por la hegemonía social todosanteña: extranjeros, principalmente estadounidenses y canadienses, mexicanos no sudcalifornianos y todosanteños.

Casa Santos Lima : from “Business as Usual” to “Expand”

OpenAIRE

Sabido, João Oliveira da Silva

2016-01-01

The case study aims to evaluate the strategy formulation of Casa Santos Lima (CSL), a Portuguese wine company, whose profile and competitive business were very useful to discuss and recommend overall strategic priorities that should guide CLS’s development and overcome with success rather challenging times ahead. From a traditional wine farm located in Alenquer, in the denominated wine producer area of Lisbon, CSL implemented a philosophy of management based on high quality ...

Lineaarse kunstiajaloo aeg on otsas / Edit András ; intervjueerinud R[eet] V[arblane

Index Scriptorium Estoniae

András, Edit

2010-01-01

Vestlus ungari kunstiteoreetiku- ja ajaloolase Edit Andrásiga, kes osales Tallinnas USA Clarki instituudi ja EKA Kunstiteaduste Instituudi seminaril, kus arutati Kesk- ja Ida-Euroopa kunstiajaloo kirjutamisviiside üle. Seminari tekkimisest, kokkusaamise põhjustest, seminari järeldustest, Eesti ja Ungari kunstiajaloo kirjutamise erinevatest põhimõtetest jm.

Mis juhtus Andres Lapeteusega? : error'ist kõrgklassi homo soveticus'e näitel / Liisa Kaljula

Index Scriptorium Estoniae

Kaljula, Liisa, 1982-

2014-01-01

Autor analüüsib 2014. a. Tallinna Semiosalongi loengute sarja põhiteema - error'i mõiste avamiseks ühe inimliigi kujunemislugu - Eesti filmiklassikast tuntud tegelaskuju Andres Lapeteuse tõusu ning langust homo soveticus'ena

Identification of an impact structure in the Upper Cretaceous of the Santos Basin in 3D seismic reflection data; Identificacao de uma estrutura de impacto no Cretaceo Superior da Bacia de Santos em sismica de reflexao 3D

Energy Technology Data Exchange (ETDEWEB)

Correia, Gustavo Alberto [PETROBRAS, Santos, SP (Brazil). Exploracao e Producao. Interpretacao e Avaliacao das Bacias da Costa Sul Polo Sul]. E-mail: gustavoac@petrobras.com.br; Menezes, Jorge Rui Correa de; Bueno, Gilmar Vital

2005-05-01

This work presents the unpublished Praia Grande impact structure, located in the Santos basin, approximately 200 km southeast from the coastline of Sao Paulo State, Brazil. The identification of this structure is based on the interpretation of three-dimensional seismic data, acquired and processed in 2004 for petroleum exploration in a PETROBRAS concession block in the Santos Basin. The main morphological elements imposed on Upper Cretaceous rocks are a structural high in the center of the crater, an adjacent ring syncline, and, externally, several concentric circular listric normal faults. The structure is apparently well preserved from erosion, measures around 20 km in diameter, is buried by 4 km of rocks and occurred in the Santonian (85,8-83,5 Ma). (author)

The ABC of Biofilm Drug Tolerance: the MerR-Like Regulator BrlR Is an Activator of ABC Transport Systems, with PA1874-77 Contributing to the Tolerance of Pseudomonas aeruginosa Biofilms to Tobramycin.

Science.gov (United States)

Poudyal, Bandita; Sauer, Karin

2018-02-01

A hallmark of biofilms is their tolerance to killing by antimicrobial agents. In Pseudomonas aeruginosa , biofilm drug tolerance requires the c-di-GMP-responsive MerR transcriptional regulator BrlR. However, the mechanism by which BrlR mediates biofilm drug tolerance has not been elucidated. Here, we demonstrate that BrlR activates the expression of at least 7 ABC transport systems, including the PA1874-PA1875-PA1876-PA1877 (PA1874-77) operon, with chromatin immunoprecipitation and DNA binding assays confirming BrlR binding to the promoter region of PA1874-77. Insertional inactivation of the 7 ABC transport systems rendered P. aeruginosa PAO1 biofilms susceptible to tobramycin or norfloxacin. Susceptibility was linked to drug accumulation, with BrlR contributing to norfloxacin accumulation in a manner dependent on multidrug efflux pumps and the PA1874-77 ABC transport system. Inactivation of the respective ABC transport system, furthermore, eliminated the recalcitrance of biofilms to killing by tobramycin but not norfloxacin, indicating that drug accumulation is not linked to biofilm drug tolerance. Our findings indicate for the first time that BrlR, a MerR-type transcriptional activator, activates genes encoding several ABC transport systems, in addition to multiple multidrug efflux pump genes. Moreover, our data confirm a BrlR target contributing to drug tolerance, likely countering the prevailing dogma that biofilm tolerance arises from a multiplicity of factors. Copyright © 2018 American Society for Microbiology.

Impacto dos Royalties do Petróleo no PIB Per Capita dos Municípios do Estado do Espírito Santo, BrasilOil Royalties Effects on the Per Capita GDP in the cities of Espirito Santo, BrazilEl Impacto de los Royalties del Petróleo en el PIB Per Capita de los Municipios del Estado de Espírito Santo, Brasil

Directory of Open Access Journals (Sweden)

RIBEIRO, Edivan Guidote

2010-03-01

Full Text Available RESUMOIdentificar os impactos que a política pública provoca na economia é essencial para a sua formulação e para o direcionamento da aplicação dos recursos financeiros auferidos pelo Estado. Este trabalho estuda a política pública brasileira de royalties de petróleo e gás natural e tem como objetivo identificar os efeitos das receitas de royalties dos governos municipais do Estado do Espírito Santo, no PIB per capita dos respectivos municípios. Os dados utilizados neste estudo correspondem aos 78 municípios de que se compõe o Estado, entre os anos de 1999 e 2004. Por meio de um modelo estatístico de dados em painel equilibrado, procedeu-se à estimação do modelo para sua efetiva análise. Os resultados mostraram que não há evidências dos impactos dessas políticas no PIB per capita nos municípios do Espírito Santo.ABSTRACTThe identification of the economical effects of public policies is essential for the formulation of such policies, as well as for the adequate allocation of the financial resources obtained by the government. The present work studies the Brazilian public policies regarding oil and natural gas royalties. Its main goal is to uncover the effects of royalties’ revenues on the per capita GDP at the city level in the state of Espirito Santo, Brazil. The data correspond to the 78 cities comprising the Brazilian state, from 1999 to 2004. An econometric model, using balanced panel data, was used to estimate the effects. The results indicate that there is no evidence of impact of these public policies on the per capita GDP of the cities of Espirito Santo.RESUMENLa identificación de los impactos que la política pública produce en la economía es esencial para su formulación y para orientar la aplicación de los recursos financieros obtenidos por el estado. Este trabajo estudia la política pública brasileña de los royalties del petróleo y del gas natural y tiene la finalidad de identificar los efectos del

Piperlongumine selectively suppresses ABC-DLBCL through inhibition of NF-κB p65 subunit nuclear import

Energy Technology Data Exchange (ETDEWEB)

Niu, Mingshan [Blood Diseases Institute, Xuzhou Medical College, Xuzhou, Jiangsu (China); Jiangsu Key Laboratory of Bone Marrow Stem Cell, Xuzhou Medical College, Xuzhou, Jiangsu (China); Department of Hematology, Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu (China); Shen, Yangling; Xu, Xiaoyu [Blood Diseases Institute, Xuzhou Medical College, Xuzhou, Jiangsu (China); Jiangsu Key Laboratory of Bone Marrow Stem Cell, Xuzhou Medical College, Xuzhou, Jiangsu (China); Yao, Yao; Fu, Chunling [Blood Diseases Institute, Xuzhou Medical College, Xuzhou, Jiangsu (China); Jiangsu Key Laboratory of Bone Marrow Stem Cell, Xuzhou Medical College, Xuzhou, Jiangsu (China); Department of Hematology, Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu (China); Yan, Zhiling [Department of Hematology, Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu (China); Wu, Qingyun [Blood Diseases Institute, Xuzhou Medical College, Xuzhou, Jiangsu (China); Jiangsu Key Laboratory of Bone Marrow Stem Cell, Xuzhou Medical College, Xuzhou, Jiangsu (China); Department of Hematology, Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu (China); Cao, Jiang; Sang, Wei [Department of Hematology, Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu (China); Zeng, Lingyu [Blood Diseases Institute, Xuzhou Medical College, Xuzhou, Jiangsu (China); Jiangsu Key Laboratory of Bone Marrow Stem Cell, Xuzhou Medical College, Xuzhou, Jiangsu (China); Department of Hematology, Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu (China); Li, Zhenyu [Department of Hematology, Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu (China); Liu, Xuejiao, E-mail: liuxuejiao0923@126.com [Insititute of Nervous System Diseases, Xuzhou Medical College, Xuzhou, Jiangsu (China); and others

2015-07-10

Constitutive NF-κB activation is required for survival of activated B cell-like subtype of diffuse large B cell lymphoma (ABC-DLBCL). However, current NF-κB targeting strategies lack cancer cell specificity. Here, we identified a novel inhibitor, piperlongumine, features direct binding to NF-κB p65 subunit and suppression of p65 nuclear import. This was accompanied by NF-κB reporter activity suppression and NF-κB target gene downregulation. Moreover, mutation of Cys{sup 38} to Ser in p65 abolished this effect of piperlongumine on inhibition of p65 nuclear import. Furthermore, we show that piperlongumine selectively inhibited proliferation and induced apoptosis of ABC-DLBCL cells. Most notably, it has been reported that piperlongumine did not affect normal cells even at high doses and was nontoxic to animals. Hence, our current study provides new insight into piperlongumine's mechanism of action and novel approach to ABC-DLBCL target therapy. - Highlights: • Current NF-κB targeting strategies lack cancer cell specificity. • Piperlongumine inhibits NF-κB p65 subunit nuclear import via directly binding to p65. • Piperlongumine selectively inhibits proliferation of ABC-DLBCL cells. • This study provides a novel approach to ABC-DLBCL target therapy.

Piperlongumine selectively suppresses ABC-DLBCL through inhibition of NF-κB p65 subunit nuclear import

International Nuclear Information System (INIS)

Niu, Mingshan; Shen, Yangling; Xu, Xiaoyu; Yao, Yao; Fu, Chunling; Yan, Zhiling; Wu, Qingyun; Cao, Jiang; Sang, Wei; Zeng, Lingyu; Li, Zhenyu; Liu, Xuejiao

2015-01-01

Constitutive NF-κB activation is required for survival of activated B cell-like subtype of diffuse large B cell lymphoma (ABC-DLBCL). However, current NF-κB targeting strategies lack cancer cell specificity. Here, we identified a novel inhibitor, piperlongumine, features direct binding to NF-κB p65 subunit and suppression of p65 nuclear import. This was accompanied by NF-κB reporter activity suppression and NF-κB target gene downregulation. Moreover, mutation of Cys 38 to Ser in p65 abolished this effect of piperlongumine on inhibition of p65 nuclear import. Furthermore, we show that piperlongumine selectively inhibited proliferation and induced apoptosis of ABC-DLBCL cells. Most notably, it has been reported that piperlongumine did not affect normal cells even at high doses and was nontoxic to animals. Hence, our current study provides new insight into piperlongumine's mechanism of action and novel approach to ABC-DLBCL target therapy. - Highlights: • Current NF-κB targeting strategies lack cancer cell specificity. • Piperlongumine inhibits NF-κB p65 subunit nuclear import via directly binding to p65. • Piperlongumine selectively inhibits proliferation of ABC-DLBCL cells. • This study provides a novel approach to ABC-DLBCL target therapy

SANTOS - a two-dimensional finite element program for the quasistatic, large deformation, inelastic response of solids

Energy Technology Data Exchange (ETDEWEB)

Stone, C.M.

1997-07-01

SANTOS is a finite element program designed to compute the quasistatic, large deformation, inelastic response of two-dimensional planar or axisymmetric solids. The code is derived from the transient dynamic code PRONTO 2D. The solution strategy used to compute the equilibrium states is based on a self-adaptive dynamic relaxation solution scheme, which is based on explicit central difference pseudo-time integration and artificial mass proportional damping. The element used in SANTOS is a uniform strain 4-node quadrilateral element with an hourglass control scheme to control the spurious deformation modes. Finite strain constitutive models for many common engineering materials are included. A robust master-slave contact algorithm for modeling sliding contact is implemented. An interface for coupling to an external code is also provided. 43 refs., 22 figs.

Bats from the Restinga of Praia das Neves, state of Espírito Santo, Southeastern Brazil

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Luz, J. L.

2009-01-01

Full Text Available Studies on bat richness and diversity in coastal sand dunes (‘restinga’ are still scarce. Therefore, the objectives of thepresent study were to estimate bat richness in the restinga of Praia das Neves (state of Espírito Santo, southeasternBrazil and to analyze species abundance. Ten sampling nights were carried out in May and July 2008, resulting in asampling effort of 21,847.5 h.m2. We captured 125 individuals from 17 bat species. In this study, Tonatia saurophilawas recorded for the first time not only in the state of Espírito Santo but also in the restinga ecosystem. The mostabundant species was Artibeus lituratus with 32% of all captures. Surveys in coastal restingas are urgently needed inorder to obtain more information about the bats living in this environment.

Similarities and dissimilarities between the movement ABC-2 and the Zurich neuromotor assessment in children with suspected developmental coordination disorder.

Science.gov (United States)

Kakebeeke, Tanja H; Egloff, Kristin; Caflisch, Jon; Chaouch, Aziz; Rousson, Valentin; Largo, Remo H; Jenni, Oskar G

2014-11-01

An established tool for the assessment of motor performance in children with developmental coordination disorder (DCD) is the Movement-ABC-2 (M-ABC-2). The Zurich Neuromotor Assessment (ZNA) is also widely used for the evaluation of children's motor performance, but has not been compared with the M-ABC-2. Fifty-one children (39 males) between 5 and 7 years of age with suspected DCD were assessed using the M-ABC-2 and the ZNA. Rank correlations between scores of different test components were calculated. The structure of the tests was explored using canonical-correlation analysis. The correlation between total scores of the two motor tests was reasonable (0.66; pABC-2, due to poor performance in the fine motor adaptive component and increased contralateral associated movements (CAM). The canonical-correlation analysis revealed that ZNA measures components like pure motor skills and CAM that are not represented in the M-ABC-2. Furthermore, there was also no equivalent for the aiming and catching items of the M-ABC-2 in ZNA. The two tests measure different motor characteristics in children with suspected DCD and, thus, can be used complementary for the diagnosis of the disorder. Copyright © 2014. Published by Elsevier Ltd.

Cetaceans trading monitoring during seismic survey in North Fluminense (Rio de Janeiro) and South Capixaba (Espirito Santo) coasts; Monitoramento de encalhe de cetaceos durante levantamento de dados sismicos na costa norte fluminense (Rio de Janeiro) e sul capixaba (Espirito Santo)

Energy Technology Data Exchange (ETDEWEB)

Amaro, Thays P.C.; Carloni, Giuliano G.; Erber, Claudia; Sabino, Carla M. [Ecologus Engenharia Consultiva, Rio de Janeiro, RJ (Brazil); Uller, George A. [CGGVeritas, Rio de Janeiro, RJ (Brazil)

2008-07-01

The objective of this research is to present the results of the cetaceans stranding monitoring developed during and after the seismic survey in the north area of Rio de Janeiro and south of Espirito Santo. The monitoring lasted six months, reaching 200 km of beaches, from the Rio de Janeiro North up to the Espirito Santo South coasts. It was conducted by 34 monitors, who covered predefined beach sections daily, registering the stranded animals. At the end of the project, 15 cetaceans stranded were registered. The species Sotalia guianensis was prevailing in number and distribution. Megaptera novaeangliae was the second specie in geographic distribution and number of registers. The other species identified were Tursiops truncatus and Peponocephala electra. (author)

An Analysis of the Factors Influencing the Adoption of Activity Based Costing (ABC in the Financial Sector in Jamaica

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Phillip C. James

2013-07-01

Full Text Available Financial institutions are increasingly operating in a highly competitively environment and therefore cost management has become an imperative. This paper investigates the factors influencing the adoption of activity-based costing (ABC methodology within the financial sector in Jamaica. Quantitative analysis was done using the generalized linear logistic regression model. The results show that there are three main factors that are statistically significant in the decision to implement an ABC system, these are: companies perception of the ability of ABC to assist in cost control, the proportion of overhead to total cost and finally, the action of competitors, that is, whether a competitor adopts the ABC methodology

Nesting of Dermochelys coriacea (Testudines, Dermochelyidae in the city of Vila Velha, Espírito Santo, Brazil

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Luis Felipe Silva Pereira Mayorga

2012-06-01

Full Text Available Worldwide, the leatherback turtle (Dermochelys coriacea is seriously threatened with extinction, especially due to accidental catches by amateur and professional fisherman. In Brazil, the only recurrent breeding sites for this species are located along the northern coast of the state of Espírito Santo, although spawning has been occasionally recorded in other states. In February 2010, a nest of D. coriacea was found in Vila Velha, Espírito Santo (20º28’30”S, 40º20’48”W, which contained 132 eggs and a stillborn. Four dead hatchlings were also found scattered within five meters of the nest. The coast of Vila Velha is not considered a breeding site for this species.

Arturo Andrés Roig, lector de Spinoza Arturo Andrés Roig, Spinoza Reader

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Gerardo Oviedo

2010-06-01

Full Text Available La categoría spinoziana de conatus ocupa un puesto central en la arquitectónica discursiva de la filosofía práctica de Arturo Andrés Roig. Se trata de un fundamento previo del saber práctico-moral que oficia de figura explicativa originaria, pues el conatus concierne a una dimensión primaria de los entes. Su status teórico no se reduce por tanto a reconocer un aspecto antropológico entre otros, sino que adquiere un carácter vertebrador en el conjunto de las estrategias de fundamentación de la idea de "moral emergente" propuesta por nuestro filósofo. Nosotros estimamos que la condición ontológica del conatus es una instancia determinante de los planteos éticos y políticos de Arturo Roig. Dicha inflexión spinozista tan patente, sin embargo, no es tenida suficientemente en cuenta en algunas lecturas especializadas de la Argentina. En consecuencia, nos proponemos en primer término destacar la función constructiva que ese momento spinoziano posee en el pensamiento del maestro mendocino, ciñéndonos a un tratamiento de los textos en donde esa fuerza conceptual se torna más visible, sin excluir por cierto otros tratamientos concomitantes. Ello nos permitirá, en un segundo nivel más historiográfico de análisis, revalorar la recepción de Spinoza en los escritos de Arturo Roig.The Spinoza conatus category occupies a central place in the architectural discourse of practical philosophy of Arturo Andres Roig. This is a preliminary basis of practical knowledge and moral figure that offers originating explanation, as the conatus concerns a primary dimension of entities. Its theoretical status is not reduced only to recognizing anthropological aspect among others, but acquires a backbone in the set of strategies to substantiate the idea of "emerging moral" given by our philosopher. We believe that the ontological status is an instance of conatus determinant of ethical and political layout of Arturo Roig. Spinoza said turning so clearly

Structure of the nucleotide-binding domain of a dipeptide ABC transporter reveals a novel iron-sulfur cluster-binding domain.

Science.gov (United States)

Li, Xiaolu; Zhuo, Wei; Yu, Jie; Ge, Jingpeng; Gu, Jinke; Feng, Yue; Yang, Maojun; Wang, Linfang; Wang, Na

2013-02-01

Dipeptide permease (Dpp), which belongs to an ABC transport system, imports peptides consisting of two or three L-amino acids from the matrix to the cytoplasm in microbes. Previous studies have indicated that haem competes with dipeptides to bind DppA in vitro and in vivo and that the Dpp system can also translocate haem. Here, the crystal structure of DppD, the nucleotide-binding domain (NBD) of the ABC-type dipeptide/oligopeptide/nickel-transport system from Thermoanaerobacter tengcongensis, bound with ATP, Mg(2+) and a [4Fe-4S] iron-sulfur cluster is reported. The N-terminal domain of DppD shares a similar structural fold with the NBDs of other ABC transporters. Interestingly, the C-terminal domain of DppD contains a [4Fe-4S] cluster. The UV-visible absorbance spectrum of DppD was consistent with the presence of a [4Fe-4S] cluster. A search with DALI revealed that the [4Fe-4S] cluster-binding domain is a novel structural fold. Structural analysis and comparisons with other ABC transporters revealed that this iron-sulfur cluster may act as a mediator in substrate (dipeptide or haem) binding by electron transfer and may regulate the transport process in Dpp ABC transport systems. The crystal structure provides a basis for understanding the properties of ABC transporters and will be helpful in investigating the functions of NBDs in the regulation of ABC transporter activity.

Statistical zonation technique and its application to the San Andres reservoir in the Poza Rica area, Vera Cruz, Mexico

Energy Technology Data Exchange (ETDEWEB)

Campa, M F; Romero, M R

1969-01-01

A statistical zonation technique developed by J.D. Testerman is presented referring to its application to the San Andres reservoir in the Poza Rica area in Veracruz, Mex. The method is based on a statistical technique which permits grouping of similar values of certain parameter, i.e., porosity, for individual wells within a field. The resulting groups or zones are used in a correlation analysis to deduce whether there is continuity of porosity in any direction. In the San Andres reservoir, there is a continuity of the porous media on NE-SW direction. This is an important fact for the waterflooding project being carried on.

Prevalence and Associated Risk Factors of Bronchial Asthma in Children in Santo Domingo, Dominican Republic.

Science.gov (United States)

Mejias, Stephanie G; Ramphul, Kamleshun

2018-02-20

Background Bronchial asthma is an important health problem worldwide. There is insufficient data on the prevalence of bronchial asthma among school children in Santo Domingo, Dominican Republic. Objective The objective of this study is to assess the prevalence of asthma and its related risk factors among school children in Santo Domingo, Dominican Republic. Materials and methods A cross-sectional study using a modified questionnaire was conducted in Santo Domingo among 600 children aged three to 11 eleven years. The prevalence of asthma and its associated risk factors such as birth order, family history of asthma, family history of allergy, exposure to pets at home, exposure to tobacco smoke, and source of fuel used at home were collected. The relevant data collected was analyzed using the Statistical Package for the Social Sciences (SPSS) 24.0. (IBM Corp., Armonk, NY) software. Results The prevalence of asthma was found to be 22.0%. Age, family history of asthma, family history of allergy, exposure to tobacco smoke, and birth order showed statistical significance. The source of fuel used at home, gender, and exposure to pets were not statistically significant to be considered as risk factors associated with asthma in the population studied. Conclusion With an asthma prevalence of 22.0% in the pediatric population, the Dominican Republic has one of the highest national rates of asthma in the pediatric population in Latin America. Proper education, screening, and prevention can help lower the burden of this disease economically and socially.

Learning the ABCs: Activity based costing in waste operations

International Nuclear Information System (INIS)

Zocher, Marc A.

1992-01-01

The United States Department of Energy (DOE) is facing a challenging new national role based on current world events, changing public perception and awareness, and a legacy of wastes generated in the past. Clearly, the DOE must put mechanisms in place to comply with environmental rules, regulations, and good management practices so that public health risk is minimized while programmatic costs are controlled. DOE has begun this process and has developed a Five-Year Plan to describe the activities necessary to comply with both cleanup, or environmental restoration, and waste management of existing waste streams. The focus of this paper is how to best manage the treatment, storage, disposal, and transportation of waste throughout the DOE weapons complex by using Activity Based Costing (ABC) to both plan and control expenditures in DOE Waste Management (WM). The basics of ABC, along with an example, will be detailed. (author)

Surface roughness optimization in machining of AZ31 magnesium alloy using ABC algorithm

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Abhijith

2018-01-01

Full Text Available Magnesium alloys serve as excellent substitutes for materials traditionally used for engine block heads in automobiles and gear housings in aircraft industries. AZ31 is a magnesium alloy finds its applications in orthopedic implants and cardiovascular stents. Surface roughness is an important parameter in the present manufacturing sector. In this work optimization techniques namely firefly algorithm (FA, particle swarm optimization (PSO and artificial bee colony algorithm (ABC which are based on swarm intelligence techniques, have been implemented to optimize the machining parameters namely cutting speed, feed rate and depth of cut in order to achieve minimum surface roughness. The parameter Ra has been considered for evaluating the surface roughness. Comparing the performance of ABC algorithm with FA and PSO algorithm, which is a widely used optimization algorithm in machining studies, the results conclude that ABC produces better optimization when compared to FA and PSO for optimizing surface roughness of AZ 31.

Chondroitinase ABC plus bone marrow mesenchymal stem cells for repair of spinal cord injury☆

Science.gov (United States)

Zhang, Chun; He, Xijing; Li, Haopeng; Wang, Guoyu

2013-01-01

As chondroitinase ABC can improve the hostile microenvironment and cell transplantation is proven to be effective after spinal cord injury, we hypothesized that their combination would be a more effective treatment option. At 5 days after T8 spinal cord crush injury, rats were injected with bone marrow mesenchymal stem cell suspension or chondroitinase ABC 1 mm from the edge of spinal cord damage zone. Chondroitinase ABC was first injected, and bone marrow mesenchymal stem cell suspension was injected on the next day in the combination group. At 14 days, the mean Basso, Beattie and Bresnahan score of the rats in the combination group was higher than other groups. Hematoxylin-eosin staining showed that the necrotic area was significantly reduced in the combination group compared with other groups. Glial fibrillary acidic protein-chondroitin sulfate proteoglycan double staining showed that the damage zone of astrocytic scars was significantly reduced without the cavity in the combination group. Glial fibrillary acidic protein/growth associated protein-43 double immunostaining revealed that positive fibers traversed the damage zone in the combination group. These results suggest that the combination of chondroitinase ABC and bone marrow mesenchymal stem cell transplantation contributes to the repair of spinal cord injury. PMID:25206389

On minimal coupling of the ABC-superparticle to supergravity background

OpenAIRE

Galajinsky, A. V.; Gitman, D. M.

1998-01-01

By rigorous application of the Hamiltonian methods we show that the ABC-formulation of the Siegel superparticle admits consistent minimal coupling to external supergravity. The consistency check proves to involve all the supergravity constraints.

Intestinal parasites in a quilombola community of the Northern State of Espírito Santo, Brazil

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Schayra Minine Damazio

2013-06-01

Full Text Available The aim of this study was to determine the occurrence of intestinal parasites in a quilombola community from the northern Espírito Santo, Brazil. Descendants of slaves who arrived in Brazil in the sixteenth century, this population settled in the municipality of São Mateus in 1858. Fresh fecal samples from 82 individuals who agreed to participate in the study were collected between August 2009 and July 2010, and immediately sent to the Clinical Laboratory of the Centro Universitário Norte do Espírito Santo of the Universidade Federal do Espírito Santo for analysis. Out of all the participants, 36 (43.9% were male and 46 (56.1% were female, whose ages ranged from six to 85 years. The study of the occurrence of intestinal parasites indicated that 35 individuals (42.7% were infected with at least one intestinal parasite. Among helminths, the most frequent were hookworms, with a rate of 14.6%. With regard to protozoa, Entamoeba coli, Entamoeba histolytica/Entamoeba dispar and Endolimax nana stood out, with frequencies of 23.2%, 8.5% and 4.9%, respectively. The occurrence of biparasitism was observed in 13 of the 82 subjects, accounting for 15.8%, and no cases of multiple parasitic infections were observed. It was concluded that the reduction of cases of intestinal diseases due to parasites will only be achieved with the improvement of basic sanitation and quality of life of quilombola populations.

Human sporotrichosis beyond the epidemic front reveals classical transmission types in Espírito Santo, Brazil.

Science.gov (United States)

de Araujo, Mariceli L; Rodrigues, Anderson M; Fernandes, Geisa F; de Camargo, Zoilo P; de Hoog, G Sybren

2015-08-01

Sporotrichosis has emerged as the main subcutaneous mycosis of humans and animals around the world. With particular differences in frequency, the major species includes Sporothrix brasiliensis, S. schenckii, S. globosa and S. luriei. In Brazil, the main aspect of this epidemic is based on the zoonotic transmission through the scratches and bites of diseased cats contaminated with S. brasiliensis. Areas free of feline sporotrichosis are poorly characterised in Brazil. We investigated by molecular tools the epidemiology of human sporotrichosis in the Espírito Santo (ES) state, an area adjacent to Rio de Janeiro where is the epicentre of the long-lasting outbreak of cat-transmitted sporotrichosis. The human cases in the ES state reveal the prevalence of classical transmission types where subjects are mainly infected by accidental traumatic inoculation during manipulation of contaminated plant material. In agreement with an environmental source, Sporothrix schenckii was the major aetiological agent in the classical transmission. Unlike Rio de Janeiro, this study shows that cat-transmitted epidemic in Espírito Santo is still scanty, although the geographic proximity and similar climatic features. Sporothrix brasiliensis was the agent in the feline-transmitted cases. Sporothrix globosa was isolated from a patient with fixed cutaneous lesions that did not report any contact with diseased animals. In conclusion, beyond the borders of Rio de Janeiro epidemic, agents of sporotrichosis in Espírito Santo show a scattered occurrence with high species diversity. © 2015 Blackwell Verlag GmbH.

Finanční analýza účetní jednotky ABC/Financial Analysis of Company ABC

OpenAIRE

Kaprálová, Aneta

2009-01-01

This thesis is focused on financial analysis of company ABC that works in rubber industry. First part is aimed at theoretical interpretation of financial analysis, its goals, history, users and sources. Attention is paid to sources of information especially financial statements. Further basic methods are defined, which financial analysis uses. Ratios are described in this thesis above all. At the close there is practical display of financial analysis based on data from financial statements of...

Brain barriers and functional interfaces with sequential appearance of ABC efflux transporters during human development

DEFF Research Database (Denmark)

Møllgård, Kjeld; Dziegielewska, Katarzyna M.; Holst, Camilla B.

2017-01-01

Adult brain is protected from entry of drugs and toxins by specific mechanisms such as ABC (ATP-binding Cassette) efflux transporters. Little is known when these appear in human brain during development. Cellular distribution of three main ABC transporters (ABCC1, ABCG2, ABCB1) was determined...... at blood-brain barriers and interfaces in human embryos and fetuses in first half of gestation. Antibodies against claudin-5 and-11 and antibodies to α-fetoprotein were used to describe morphological and functional aspects of brain barriers. First exchange interfaces to be established, probably at 4...... three transporters. Results provide evidence for sequential establishment of brain exchange interfaces and spatial and temporal timetable for three main ABC transporters in early human brain....

The chemistry of ABC

Energy Technology Data Exchange (ETDEWEB)

Jensen, R.J. [Los Alamos National Laboratory, NM (United States)

1995-10-01

ABC stand for accelerator based conversion of Pu. It is a unique approach to Pu destruction that allows for a well controlled and complete burn of Pu as may be required by treaty or policy. The central idea of the approach is to provide a spallation source of neutrons that allows the operation of a fissioning system without a critical mass and at a K effective less than one. Material to be fissioned is suspended in a molten salt medium for high temperature control and on-line removal of neutron absorbing fission products. This paper discusses the issues associated with the selection and operation of a molten salt chemical system: redox control, product removal, material feed, solubilities, deposition control, and a host of operational procedures.

Analysis of behavioral intention on ABC system adoption: Model of information systems technology and success acceptance

Directory of Open Access Journals (Sweden)

Baiq Nensi Veni Indipenrian

2015-12-01

Full Text Available This study aims to examine the effect of individual behavioral change on the adoption of activity- based costing (ABC system and its usage, using Unified Theory of Accep-tance and Use of Technology (UTAUT and Information System Success Model. The sample involves 78 respondents who have positions as financial manager, controller manager, accounting manager, and production manager in mid-sized manufacturing companies in East java. The data were collected by survey method. This study used a Partial Least Square (PLS as the data analysis method. It was found that not all of the main UTAUT models were supported, because performance expectancy and effort expectancy have no effect on behavioral intention and use behavior to adopt ABC system. Whereas, social factors, information quality and facilitating conditions had a positive effect on behavioral intention and use behavior to adopt ABC system. The different results of this study with several previous studies are probably caused by the differences in the context of system, culture and characteristics of the sample. The implication of this study is not only to propose a theoretical framework for researches in future, but also useful for companies to optimize the use of ABC system that should be supported by top level and mid-level management and the readiness of the individu-als to accept the adoption of the ABC system.

Despedida al maestro Arturo Andrés Roig (1922 – 2012

Directory of Open Access Journals (Sweden)

Enrique Dussel

2015-07-01

Full Text Available En ocasión del fallecimiento de Arturo Andrés Roig (Doctor Honoris Causa por las Universidades Nacional de Río Cuarto, Argentina; Nacional de San Luis, Argentina; Autónoma de Managua, Nicaragua. Profesor Honorario en las Universidades Nacional del Comahue -Argentina-, y Andina Simón Bolívar -Ecuador- queremos sumarnos a la larga serie de homenajes que ha recibido. Para ello, reproducimos aquí tres memoriales dedicados al maestro por filósofos americanos.

Preclinical properties and human in vivo assessment of 123 I-ABC577 as a novel SPECT agent for imaging amyloid-β

Science.gov (United States)

Okumura, Yuki; Kobayashi, Ryohei; Onishi, Takako; Shoyama, Yoshinari; Barret, Olivier; Alagille, David; Jennings, Danna; Marek, Kenneth; Seibyl, John; Tamagnan, Gilles; Tanaka, Akihiro; Shirakami, Yoshifumi

2016-01-01

Abstract Non-invasive imaging of amyloid-β in the brain, a hallmark of Alzheimer’s disease, may support earlier and more accurate diagnosis of the disease. In this study, we assessed the novel single photon emission computed tomography tracer 123 I-ABC577 as a potential imaging biomarker for amyloid-β in the brain. The radio-iodinated imidazopyridine derivative 123 I-ABC577 was designed as a candidate for a novel amyloid-β imaging agent. The binding affinity of 123 I-ABC577 for amyloid-β was evaluated by saturation binding assay and in vitro autoradiography using post-mortem Alzheimer’s disease brain tissue. Biodistribution experiments using normal rats were performed to evaluate the biokinetics of 123 I-ABC577. Furthermore, to validate 123 I-ABC577 as a biomarker for Alzheimer’s disease, we performed a clinical study to compare the brain uptake of 123 I-ABC577 in three patients with Alzheimer’s disease and three healthy control subjects. 123 I-ABC577 binding was quantified by use of the standardized uptake value ratio, which was calculated for the cortex using the cerebellum as a reference region. Standardized uptake value ratio images were visually scored as positive or negative. As a result, 123 I-ABC577 showed high binding affinity for amyloid-β and desirable pharmacokinetics in the preclinical studies. In the clinical study, 123 I-ABC577 was an effective marker for discriminating patients with Alzheimer’s disease from healthy control subjects based on visual images or the ratio of cortical-to-cerebellar binding. In patients with Alzheimer’s disease, 123 I-ABC577 demonstrated clear retention in cortical regions known to accumulate amyloid, such as the frontal cortex, temporal cortex, and posterior cingulate. In contrast, less, more diffuse, and non-specific uptake without localization to these key regions was observed in healthy controls. At 150 min after injection, the cortical standardized uptake value ratio increased by ∼60% in patients

La orden de caballería del Santo Sepulcro de Jerusalén

Directory of Open Access Journals (Sweden)

Antonio MARTÍNEZ TEIXIDÓ

2009-12-01

Full Text Available RESUMEN: La orden del Santo Sepulcro nace en Jerusalén el año 1099, poco después de que fuera conquistada la ciudad por Godofredo de Bouillon durante la Primera Cruzada. Este caudillo borgoñón, tras ser aceptado como protector del Santo Sepulcro, organizó un servicio religioso con canónigos del clero regular, a cuyo frente nombró a un prior. Creó asimismo una guardia de honor con caballeros cruzados que prestaron voto de obediencia con el juramento de consagrar su vida a la defensa del Santo Sepulcro.La orden del Santo Sepulcro se distinguió por unir el carácter militar de sus caballeros con el religioso de sus canónigos. Los caballeros, bajo la obediencia del patriarca latino de Jerusalén, prior general de la orden, concretaron su organización durante el reinado de Balduino I (1100-1118.Tras la caída de Sanjuan de Acre (1291, los caballeros y canónigos de la orden se dispersaron por los reinos europeos que manteníano prioratos. El papa Inocencio VIII en el año 1489 incorporó la orden con todos sus bienes a los Hospitalarios de San Juan, pero siete años después el papa Alejandro VI anuló dicha decisión.A partir de entonces surgieron diversas iniciativas para revitalizar la orden, especialmente en el año 1558 en el que se ofreció a Felipe II de España el Gran Maestrazgo de la orden. La última tentativa se produce en 1818, al autoproclamarse Luis XVIII de Francia soberano y protector del Santo Sepulcro. En el año 1847, resurge la orden cuando el papa Pío IX restaura el Patriarcado Latino de Jerusalén y concede al patriarca el Gran Maestrazgo de la orden.ABSTRACT: In 1099, after the capture of Jerusalem, and the establishment of the Crusader Kingdom, there was a distinct corps of professed Knights dedicated to the defence of the newly won territory. Godfrey of Bouillon created an «honour guard» for the Holy Sepulchre. It was a unique combination of ecclesiastical and military elements closely related to free the Holy

Why activity based costing (ABC) is still tagging behind the traditional costing in Malaysia?

OpenAIRE

Rasiah, Devinaga

2011-01-01

This study compares activity-based costing (ABC) model and traditional costing method in Malaysia. Activity based costing (ABC) which was developed into the manufacturing/service sectors in Malaysia. It calculates the cost and performance of activities, resources and cost objects. It can be considered as an alternative model to Traditional Cost-based accounting systems. In this study the results indicated that most operations managers believed that their present cost systems were adequate for...

Psychoactive substances and the provision of specialized care: the case of Espirito Santo Substâncias psicoativas e a provisão de cuidados especializados: o caso do Espírito Santo

Directory of Open Access Journals (Sweden)

Marluce Miguel de Siqueira

2007-12-01

Full Text Available OBJECTIVE: In this study, we conducted a survey of all the institutions that provide treatment for psychoactive substances in the state of Espirito Santo, Brazil during the period 2004-2005. METHOD: We used a snowball sampling technique to include all the treatment facilities in our State in which we employed a semi-structured interview instrument for key informants at each institution. We present descriptive results and test differences between groups using the Chi-square test. RESULTS: In Espirito Santo, 250 institutions provide treatment for psychoactive substances and are distributed as follows: governmental (17.6%, nongovernmental (22.8%, and self-help groups (59.6%. Of these 250 institutions, 85 provide direct care, with the majority found in the Central region (70.6% and followed by the Northern (15.3% and Southern (14.1% regions. The majority of those that provide direct care are private nonprofit centers (16.8% institutions with ties to religious organizations make up nearly one-third (30.6% of direct care providers. The drugs most consumed by those seeking care are alcohol (82.4%, tobacco (81.2% and marijuana (68.2%. The institutions generally give assistance to people in the 26-45 years age group (89.4%; with regard to gender, the institutions take care of: men (31.8%, women (5.9%, and both sexes (56.5%. The treatment models most used are psychosocial (58.8%, therapeutic community (47.1% and biomedical (43.5% and the work is evaluated through the team technique (72.9 %. CONCLUSIONS: In the state of Espirito Santo, indirect care services are many times greater than those that offer direct care and the majority of all services are in the Central region. The populations in the mainland have a comparative disadvantage when it comes to treatment options for psychoactive substance use. We observed that a significant number of institutions that provide drug abuse treatment have financial support from religious organizations. The Espirito

Antibiotic Resistance Mediated by the MacB ABC Transporter Family: A Structural and Functional Perspective

Directory of Open Access Journals (Sweden)

Nicholas P. Greene

2018-05-01

Full Text Available The MacB ABC transporter forms a tripartite efflux pump with the MacA adaptor protein and TolC outer membrane exit duct to expel antibiotics and export virulence factors from Gram-negative bacteria. Here, we review recent structural and functional data on MacB and its homologs. MacB has a fold that is distinct from other structurally characterized ABC transporters and uses a unique molecular mechanism termed mechanotransmission. Unlike other bacterial ABC transporters, MacB does not transport substrates across the inner membrane in which it is based, but instead couples cytoplasmic ATP hydrolysis with transmembrane conformational changes that are used to perform work in the extra-cytoplasmic space. In the MacAB-TolC tripartite pump, mechanotransmission drives efflux of antibiotics and export of a protein toxin from the periplasmic space via the TolC exit duct. Homologous tripartite systems from pathogenic bacteria similarly export protein-like signaling molecules, virulence factors and siderophores. In addition, many MacB-like ABC transporters do not form tripartite pumps, but instead operate in diverse cellular processes including antibiotic sensing, cell division and lipoprotein trafficking.

Antibiotic Resistance Mediated by the MacB ABC Transporter Family: A Structural and Functional Perspective

Science.gov (United States)

Greene, Nicholas P.; Kaplan, Elise; Crow, Allister; Koronakis, Vassilis

2018-01-01

The MacB ABC transporter forms a tripartite efflux pump with the MacA adaptor protein and TolC outer membrane exit duct to expel antibiotics and export virulence factors from Gram-negative bacteria. Here, we review recent structural and functional data on MacB and its homologs. MacB has a fold that is distinct from other structurally characterized ABC transporters and uses a unique molecular mechanism termed mechanotransmission. Unlike other bacterial ABC transporters, MacB does not transport substrates across the inner membrane in which it is based, but instead couples cytoplasmic ATP hydrolysis with transmembrane conformational changes that are used to perform work in the extra-cytoplasmic space. In the MacAB-TolC tripartite pump, mechanotransmission drives efflux of antibiotics and export of a protein toxin from the periplasmic space via the TolC exit duct. Homologous tripartite systems from pathogenic bacteria similarly export protein-like signaling molecules, virulence factors and siderophores. In addition, many MacB-like ABC transporters do not form tripartite pumps, but instead operate in diverse cellular processes including antibiotic sensing, cell division and lipoprotein trafficking. PMID:29892271

Acid mine water reclamation using the ABC process

CSIR Research Space (South Africa)

De Beer, Morris

2010-09-01

Full Text Available of about 2 to 4.5 g/L of sulphate, 250 to 1200 mg/L of Ferrous iron, 60 to 175 mg/L of Mn and 120 mg/L of Mg. The CSIR ABC desalination process, developed for AMD neutralisation and the removal of total dissolved solids from 2 600 to 360 mg/L...

Preconceptual ABC design definition and system configuration layout

International Nuclear Information System (INIS)

Barthold, W.

1995-03-01

This document is the conceptual design document for the follow-on to the Molten Salt Breeder Reactor, known as the ABC type reactor. It addresses blanket design options, containment options, off-gas systems, drainage systems, and components/layouts of the primary, secondary, and tertiary systems, and it contains a number of diagrams for the configuration of the major systems

Whole-transcriptome survey of the putative ATP-binding cassette (ABC) transporter family genes in the latex-producing laticifers of Hevea brasiliensis.

Science.gov (United States)

Zhiyi, Nie; Guijuan, Kang; Yu, Li; Longjun, Dai; Rizhong, Zeng

2015-01-01

The ATP-binding cassette (ABC) proteins or transporters constitute a large protein family in plants and are involved in many different cellular functions and processes, including solute transportation, channel regulation and molecular switches, etc. Through transcriptome sequencing, a transcriptome-wide survey and expression analysis of the ABC protein genes were carried out using the laticiferous latex from Hevea brasiliensis (rubber tree). A total of 46 putative ABC family proteins were identified in the H. brasiliensis latex. These consisted of 12 'full-size', 21 'half-size' and 13 other putative ABC proteins, and all of them showed strong conservation with their Arabidopsis thaliana counterparts. This study indicated that all eight plant ABC protein paralog subfamilies were identified in the H. brasiliensis latex, of which ABCB, ABCG and ABCI were the most abundant. Real-time quantitative reverse transcription-polymerase chain reaction assays demonstrated that gene expression of several latex ABC proteins was regulated by ethylene, jasmonic acid or bark tapping (a wound stress) stimulation, and that HbABCB15, HbABCB19, HbABCD1 and HbABCG21 responded most significantly of all to the abiotic stresses. The identification and expression analysis of the latex ABC family proteins could facilitate further investigation into their physiological involvement in latex metabolism and rubber biosynthesis by H. brasiliensis.

Convenio "Andres Bello:" Informe Final [de la] Segunda Reunion de Ministros de Educacion de la Region Andina ("Andres Bello" Agreement: Final Report of the Second Meeting of the Andean Region Ministers of Education).

Science.gov (United States)

Ministros de Educacion de la Region Andina, Lima (Peru).

This final report of the second meeting of the Andean Region Ministers of Education subscribing to the Andres Bello Agreement on education and culture contains a resume of the individual sessions and the proposals approved during that meeting. The proposals cover various educational problems and issues and begin with the Declaration of Lima which…

Computed ABC Analysis for Rational Selection of Most Informative Variables in Multivariate Data.

Science.gov (United States)

Ultsch, Alfred; Lötsch, Jörn

2015-01-01

Multivariate data sets often differ in several factors or derived statistical parameters, which have to be selected for a valid interpretation. Basing this selection on traditional statistical limits leads occasionally to the perception of losing information from a data set. This paper proposes a novel method for calculating precise limits for the selection of parameter sets. The algorithm is based on an ABC analysis and calculates these limits on the basis of the mathematical properties of the distribution of the analyzed items. The limits implement the aim of any ABC analysis, i.e., comparing the increase in yield to the required additional effort. In particular, the limit for set A, the "important few", is optimized in a way that both, the effort and the yield for the other sets (B and C), are minimized and the additional gain is optimized. As a typical example from biomedical research, the feasibility of the ABC analysis as an objective replacement for classical subjective limits to select highly relevant variance components of pain thresholds is presented. The proposed method improved the biological interpretation of the results and increased the fraction of valid information that was obtained from the experimental data. The method is applicable to many further biomedical problems including the creation of diagnostic complex biomarkers or short screening tests from comprehensive test batteries. Thus, the ABC analysis can be proposed as a mathematically valid replacement for traditional limits to maximize the information obtained from multivariate research data.

Selections from the ABC 2011 Annual Convention, Montreal, Canada

Science.gov (United States)

Whalen, D. Joel; Andersen, Ken; Campbell, Gloria; Crenshaw, Cheri; Cross, Geoffrey A.; Grinols, Anne Bradstreet; Hildebrand, John; Newman, Amy; Ortiz, Lorelei A.; Paulson, Edward; Phillabaum, Melinda; Powell, Elizabeth A.; Sloan, Ryan

2012-01-01

The 12 Favorite Assignments featured in this article were presented at the 2011 Annual Convention of the Association for Business Communication (ABC), Montreal, Canada. A variety of learning objectives are featured: delivering bad news, handling difficult people, persuasion, reporting financial analysis, electronic media, face-to-face…

Selections from the ABC 2012 Annual Convention, Honolulu, Hawaii

Science.gov (United States)

Whalen, D. Joel

2013-01-01

The 13 Favorite Assignments featured here were presented at the 2012 Association for Business Communication (ABC) Annual Convention, Honolulu, Hawaii. A variety of learning objectives are featured, including the following: enhancing resume's visual impact, interpersonal skills, social media, team building, web design, community service projects,…

Is the ABC pain scale reliable for premature babies?

Science.gov (United States)

Bellieni, Cv; Maffei, M; Ancora, G; Cordelli, D; Mastrocola, M; Faldella, G; Ferretti, E; Buonocore, G

2007-07-01

We recently developed the ABC scale to assess pain in term newborns. The aim of the present study was to assess the reliability of the scale in preterm babies. The scale consists of three cry parameters: (a) pitch of the first cry, (b) rhythmicity of the bout of crying and (c) cry constancy. Changes in these parameters were previously found to distinguish medium and high levels of pain as evaluated by spectral analysis of crying. We enrolled 72 babies to perform the steps usually requested to validate a scale, namely the study of the concurrent validity, specificity and sensibility. Moreover, we assessed the interjudge reliability and the clinical utility and ease of the scale. A good correlation (r = 0.68; r(2)= 0.45; p babies who underwent pain and babies who underwent non-painful stimulus.) Interobserver reliability was good: Cohen's kappa = 0.7. The good correlation between the two scales shows that the ABC scale is also reliable for premature babies.

Inhibition or knockdown of ABC transporters enhances susceptibility of adult and juvenile schistosomes to Praziquantel.

Directory of Open Access Journals (Sweden)

Ravi S Kasinathan

2014-10-01

Full Text Available Parasitic flatworms of the genus Schistosoma cause schistosomiasis, a neglected tropical disease that affects hundreds of millions. Treatment of schistosomiasis depends almost entirely on the drug praziquantel (PZQ. Though essential to treating and controlling schistosomiasis, a major limitation of PZQ is that it is not active against immature mammalian-stage schistosomes. Furthermore, there are reports of field isolates with heritable reductions in PZQ susceptibility, and researchers have selected for PZQ-resistant schistosomes in the laboratory. P-glycoprotein (Pgp; ABCB1 and other ATP binding cassette (ABC transporters remove a wide variety of toxins and xenobiotics from cells, and have been implicated in multidrug resistance (MDR. Changes in ABC transporter structure or expression levels are also associated with reduced drug susceptibility in parasitic helminths, including schistosomes. Here, we show that the activity of PZQ against schistosome adults and juveniles ex vivo is potentiated by co-administration of either the highly potent Pgp inhibitor tariquidar or combinations of inhibitors targeting multiple ABC multidrug transporters. Adult worms exposed to sublethal PZQ concentrations remain active, but co-administration of ABC transporter inhibitors results in complete loss of motility and disruption of the tegument. Notably, juvenile schistosomes (3-4 weeks post infection, normally refractory to 2 µM PZQ, become paralyzed when transporter inhibitors are added in combination with the PZQ. Experiments using the fluorescent PZQ derivative (R-PZQ-BODIPY are consistent with the transporter inhibitors increasing effective intraworm concentrations of PZQ. Adult worms in which expression of ABC transporters has been suppressed by RNA interference show increased responsiveness to PZQ and increased retention of (R-PZQ-BODIPY consistent with an important role for these proteins in setting levels of PZQ susceptibility. These results indicate that

IMG-ABC: An Atlas of Biosynthetic Gene Clusters to Fuel the Discovery of Novel Secondary Metabolites

Energy Technology Data Exchange (ETDEWEB)

Chen, I-Min; Chu, Ken; Ratner, Anna; Palaniappan, Krishna; Huang, Jinghua; Reddy, T. B.K.; Cimermancic, Peter; Fischbach, Michael; Ivanova, Natalia; Markowitz, Victor; Kyrpides, Nikos; Pati, Amrita

2014-10-28

In the discovery of secondary metabolites (SMs), large-scale analysis of sequence data is a promising exploration path that remains largely underutilized due to the lack of relevant computational resources. We present IMG-ABC (https://img.jgi.doe.gov/abc/) -- An Atlas of Biosynthetic gene Clusters within the Integrated Microbial Genomes (IMG) system1. IMG-ABC is a rich repository of both validated and predicted biosynthetic clusters (BCs) in cultured isolates, single-cells and metagenomes linked with the SM chemicals they produce and enhanced with focused analysis tools within IMG. The underlying scalable framework enables traversal of phylogenetic dark matter and chemical structure space -- serving as a doorway to a new era in the discovery of novel molecules.

Digital model of the seabed geomorphology of southern-central Espirito Santo basin and northern Campos basin; Modelo digital da geomorfologia do fundo oceanico do centro-sul da bacia do Espirito Santo e norte da bacia de Campos

Energy Technology Data Exchange (ETDEWEB)

Schreiner, Simone; Souza, Mariana Beatriz Ferraz Mendonca de; Migliorelli, Joana Paiva Robalo [Petroleo Brasileiro S. A. (PETROBRAS), Rio de Janeiro, RJ (Brazil). Unidade de Servicos de Exploracao e Producao], Emails: schreiner@petrobras.com.br, mbfms.fototerra@petrobras.com.br, joanamigli.fototerra@petrobras.com.br

2009-05-15

That communication brings the result of a bathymetric mosaic of converted in a digital model of the ocean topography, consisting of 17 seismic projects 3D, besides 17 multibeam bathymetry surveys of South-Central Espirito Santo Basin and Northern Campos Basin.

Vipsi ABC Grupp teatas kavatsusest börsile minna / Anne Oja

Index Scriptorium Estoniae

Oja, Anne, 1970-

2010-01-01

Kaubanduskontsern ABC Grupp maksis tagasi 97,2 mln. krooni eest võlakirju, juhatuse esimehe teatel kasutab ettevõtte meeskond saadud kogemusi naasmaks tulevikus avaliku ettevõtte staatusesse juba aktsiaemitendina

Comparing the results of DAADD and ABC of children included in autism spectrum disorders.

Science.gov (United States)

Barbosa, Milene Rossi Pereira; Fernandes, Fernanda Dreux Miranda

2014-01-01

To verify if there are characteristic behaviors of the different diagnosis included in the autism spectrum according to the Differential Assessment of Autism and Other Developmental Disorders (DAADD) and to the Autism Behavior Checklist (ABC). Participants were 45 individuals and their respective speech-language therapists. All therapists are graduate students working with the children for at least 1 year. This time was considered sufficient to the therapists to have the information required by the DAADD questionnaire. It is comprised by 3 protocols specifically designed to children with 2 to 4 years, 4 to 6 years and 6 to 8 years, the same criteria used to separate the research groups, G1, G2 and G3, respectively. Data referring to the ABC were retrieved from the subject's files at the Laboratório de Investigação Fonoaudiológica nos Distúrbios do Espectro do Autismo (Research Laboratory on Language Disorders in the Autism Spectrum) of the School of Medicine, Universidade de São Paulo, where it is routinely applied during the annual assessment. Answers to the different areas of DAADD are similar to the different areas of ABC. These data show data the diagnosis by DAADD is easier in older children. Although there is no significant difference, the large occurrence of Rett's syndrome diagnosis according to the DAADD was associated to higher risk for autism according to the ABC in G1. With increasing age this tendency decreases and either in G2 and G3 Autism is the most frequent diagnosis. Although the results of both questionnaires tend to agree more with increasing age, the DAADD is more sensitive in the different ages while the ABC if more specific only to older children.

Activity-Based Costing (ABC and Time-Driven Activity-Based Costing (TDABC: Applicable Methods for University Libraries?

Directory of Open Access Journals (Sweden)

Kate-Riin Kont

2011-01-01

Full Text Available Objective – This article provides an overview of how university libraries research and adapt new cost accounting models, such as “activity-based costing” (ABC and “time-driven activity-based costing” (TDABC, focusing on the strengths and weaknesses of both methods to determine which of these two is suitable for application in university libraries.Methods – This paper reviews and summarizes the literature on cost accounting and costing practices of university libraries. A brief overview of the history of cost accounting, costing, and time and motion studies in libraries is also provided. The ABC and the TDABC method, designed as a revised and easier version of the ABC by Kaplan and Anderson (Kaplan & Anderson 2004 at the beginning of the 21st century, as well as the adoption and adaptation of these methods by university libraries are described, and their strengths and weaknesses, as well as their suitability for university libraries, are analyzed. Results – Cost accounting and costing studies in libraries have a long history, the first of these dating back to 1877. The development of cost accounting and time and motion studies can be seen as a natural evolution of techniques which were created to solve management problems. The ABC method is the best-known management accounting innovation of the last 20 years, and is already widely used in university libraries around the world. However, setting up an ABC system can be very costly, and the system needs to be regularly updated, which further increases its costs. The TDABC system can not only be implemented more quickly (and thus more cheaply, but also can be updated more easily than the traditional ABC, which makes the TDABC the more suitable method for university libraries.Conclusion – Both methods are suitable for university libraries. However, the ABC method can only be implemented in collaboration with an accounting department. The TDABC method can be tested and implemented by

Harju Elekter väärtustab strateegilist partnerlust / Andres Aarma

Index Scriptorium Estoniae

Aarma, Andres

2003-01-01

Autor kirjeldab elektriseadmete ja -materjalide tootja, ettevõtte Harju Elekter edu põhjuseid läbi olulisemate strateegiliste juhtimisotsuste, personalijuhtimise, tootmise ning toodangu turustamise. Kommenteerivad Sander Danil, Jako Kotkas, Andres Vainola, Rein Siim ja Triin Palge. Diagrammid: Harju Elektri käive, eksport ja kasum, turud käibe järgi, tegevusalad käibe järgi. Skeemid: Harju Elektri tütar- ja sidusettevõtted, organisatsiooni struktuur. Vt. samas intervjuud Harju Elektri nõukogu esimehe Endel Pallaga; Harju Elektri kontsern täna. Lisad: Harju Elektri olulisemad koostöölepingud, laenude tagatised ja panditud vara

ABC of physics a very brief guide

CERN Document Server

Okun, Lev Borisovich

2012-01-01

This little book concentrates on the foundations of modern physics (its "ABC's") and its most fundamental constants: c - the velocity of light and ? - the quantum of action. First of all, the book is addressed to professional physicists, but in order to achieve maximal concentration and clarity it uses the simplest (high school) mathematics. As a result many pages of the book will be useful to college students and may appeal to a more general audience.

Strategies for neurotrophin-3 and chondroitinase ABC release from freeze-cast chitosan-alginate nerve-guidance scaffolds.

Science.gov (United States)

Francis, Nicola L; Hunger, Philipp M; Donius, Amalie E; Wegst, Ulrike G K; Wheatley, Margaret A

2017-01-01

Freeze casting, or controlled unidirectional solidification, can be used to fabricate chitosan-alginate (C-A) scaffolds with highly aligned porosity that are suitable for use as nerve-guidance channels. To augment the guidance of growth across a spinal cord injury lesion, these scaffolds are now evaluated in vitro to assess their ability to release neurotrophin-3 (NT-3) and chondroitinase ABC (chABC) in a controlled manner. Protein-loaded microcapsules were incorporated into C-A scaffolds prior to freeze casting without affecting the original scaffold architecture. In vitro protein release was not significantly different when comparing protein loaded directly into the scaffolds with release from scaffolds containing incorporated microcapsules. NT-3 was released from the C-A scaffolds for 8 weeks in vitro, while chABC was released for up to 7 weeks. Low total percentages of protein released from the scaffolds over this time period were attributed to limitation of diffusion by the interpenetrating polymer network matrix of the scaffold walls. NT-3 and chABC released from the scaffolds retained bioactivity, as determined by a neurite outgrowth assay, and the promotion of neurite growth across an inhibitory barrier of chondroitin sulphate proteoglycans. This demonstrates the potential of these multifunctional scaffolds for enhancing axonal regeneration through growth-inhibiting glial scars via the sustained release of chABC and NT-3. Copyright © 2014 John Wiley & Sons, Ltd. Copyright © 2014 John Wiley & Sons, Ltd.

Metal and trace element sediment assessment from two estuarine systems: Santos/Sao Vicente and Cananeia, State of Sao Paulo, Brazil

International Nuclear Information System (INIS)

Amorim, Eduardo Paulo de

2012-01-01

This study evaluated some toxic metals such as Cd, Hg and Pb and some other major and trace elements in surface sediment samples, from two different systems under different degrees of anthropogenic actions: the estuarine system of Santos/Sao Vicente and the southern part of the Cananeia estuary, both on the Sao Paulo state coast. Sediment samples were collected in 16 stations in the Santos/Sao Vicente estuary and 13 stations in the Cananeia estuary, during summer and winter of 2005 and 2006, in both estuaries. Three analytical techniques were used: NAA, AAS and ICP OES. NAA was used for the quantification of major element concentration levels (Ca, Fe and Na), trace elements (As, Ba, Br, Cd, Co, Cu, Cr, Cs, Hf, Rb, Sb, Sc, Se, Ta, Th, U, and Zn and rare earths elements La, Ce, Eu, Nd, Sm, Lu, Tb, Yb). ICP OES was used for determination of the concentration levels of Al, Ba, Be, Bi, B, Cd, Co, Pb, Cu, Cr, Sn, Sr, Fe, Li, Mn, Mo, Ni, Tl, Ti, V and Zn. AAS for Cd and Pb quantification through graphite furnace (GF AAS) and Hg through cold vapor generation (CV AAS). Methodology validation according to precision and accuracy was performed by reference material analyses for the three analytical techniques used. Detection and quantification limits were calculated for each element evaluated. Seasonal variations (summer and winter), spatial and temporal (2005 e 2006) variations of metals and trace elements were also evaluated. In the Santos estuary, in general, metal and trace element concentrations , organic matter content and % of pelitic fraction found in the Santos channel (area 1) were higher than those of the Santos Bay (area 2) and Sao Vicente channel (area 3). Area 1 suffers high impact from industrial activities from the Cubatao region and Santos port. The sediments from station 14 (area 3, Sao Vicente channel), showed the same behavior of those from area 1, suffering influence from the industrial pole and located in a mangrove area. In comparison with TEL and PEL

Deficiency of Functional Iron-Sulfur Domains in ABCE1 Inhibits the Proliferation and Migration of Lung Adenocarcinomas By Regulating the Biogenesis of Beta-Actin In Vitro

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Qian Yu

2017-11-01

Full Text Available Background/Aims: ATP-binding cassette transporter E1 (ABCE1, a unique ABC superfamily member that bears two Fe-S clusters, is essential for metastatic progression in lung cancer. Fe-S clusters within ABCE1 are crucial for ribosome dissociation and translation reinitiation; however, whether these clusters promote tumor proliferation and migration is unclear. Methods: The interaction between ABCE1 and β-actin was confirmed using GST pull-down. The lung adenocarcinoma (LUAD cell line A549 was transduced with lentiviral packaging vectors overexpressing either wild-type ABCE1 or ABCE1 with Fe-S cluster deletions (ΔABCE1. The role of Fe-S clusters in the viability and migration of cancer cells was evaluated using clonogenic, MTT, Transwell and wound healing assays. Cytoskeletal rearrangement was determined using immunofluorescent techniques. Results: Fe-S clusters were the key domains in ABCE1 involved in binding to β-actin. The proliferative and migratory capacity increased in cells overexpressing ABCE1. However, the absence of Fe-S clusters reversed these effects. A549 cells overexpressing ABCE1 exhibited irregular morphology and increased levels of cytoskeletal polymerization as indicated by the immunofluorescence images. In contrast, cells expressing the Fe-S cluster deletion mutant presented opposing effects. Conclusion: These results demonstrate the indispensable role of Fe-S clusters when ABCE1 participates in the proliferation and migration of LUADs by interacting with β-actin. The Fe-S clusters of ABCE1 may be potential targets for the prevention of lung cancer metastasis.

Rasch Analysis of the Activities-specific Balance Confidence (ABC) Scale in Older Adults Seeking Outpatient Rehabilitation Services.

Science.gov (United States)

Wang, Ying-Chih; Sindhu, Bhagwant; Lehman, Leigh; Li, Xiaoyan; Yen, Sheng-Che; Kapellusch, Jay

2018-03-30

Study Design Cross-sectional study of 5,012 older patients seeking outpatient rehabilitation therapy in 123 clinics. Background The Activities-Specific Balance Confidence (ABC) Scale measures confidence in performing various ambulatory activities without falling or experiencing a sense of unsteadiness. Objectives Our purposes were to: (1) examine the ABC Scale (0-100) using the Rasch analysis, (2) assess statistically reliable change, and (3) develop a functional staging to guide clinical interpretation of the patient's improvement. Methods We examined rating scale structure, item difficulty hierarchy, item fit, person-item match, separation index, differential item functioning (DIF), test precision, and unidimensionality. Additionally, we estimated the minimal detectable change (MDC) and developed a functional staging. Results Item 'walking outside on icy sidewalks' was the most difficult item, while 'reach for a small can off a shelf at eye level' was the easiest item. Overall, average patient ability estimates of 56.2 (20.3) was slightly higher than the average item difficulty estimates of 45.9 (7.8). With a separation index equaled to 3.65, the ABC items can differentiate persons into 5.2 statistically distinct strata. Most ABC items were free of DIF. For example, 'walk outside on icy sidewalks' was easier for patients who was underweight. Results supported unidimensionality of the ABC Scale, with the first factor explained 77% of the total variance. The estimated MDC was 15 points. We provided an example of functional staging application. Conclusion Results supported sound psychometric properties and clinical usage of the ABC Scale for older adults seeking outpatient rehabilitation therapy. Level of Evidence 2c. J Orthop Sports Phys Ther, Epub 30 Mar 2018. doi:10.2519/jospt.2018.8023.

Distribution and infestation levels of Crypticerya multicicatrices Kondo and Unruh (Hemiptera: Monophlebidae on San Andrés island

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Takumasa Kondo Kondo

2014-01-01

Full Text Available The fluted scale Crypticerya multicicatrices (Hemiptera: Monophlebidae is an invasive insect that became a major pest on the island of San Andrés. To generate control strategies for this insect, its distribution and infestation levels on palm species, fruit trees, leguminous trees and other plant species were determined during January 14–18, 2013. A total of 96 points were sampled in order to determine the distribution of the insect on the island. During the study, the fluted scale was found distributed throughout the island of San Andrés, including Haynes Cay and Johnny Cay. The palms were the plants with the highest levels of infestation, 70.8% had some degree of infestation (37.5% high infestation levels; followed by fruit trees which had 65.6% with some degree of infestation (30.2% high infestation levels; followed by leguminous trees which had 59.6% with some degree of infestation (13.5% high infestation levels and finally “other hosts” which had 51.1% with some level of infestation (11.5% high infestation levels. This study is the first detailed mapping of C. multicicatrices on the island of San Andrés which will become the basis for future work on the population dynamics of the fluted scale and its distribution on the island.

The jABC Approach to Rigorous Collaborative Development of SCM Applications

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Hörmann, Martina; Margaria, Tiziana; Mender, Thomas; Nagel, Ralf; Steffen, Bernhard; Trinh, Hong

Our approach to the model-driven collaborative design of IKEA's P3 Delivery Management Process uses the jABC [9] for model driven mediation and choreography to complement a RUP-based (Rational Unified Process) development process. jABC is a framework for service development based on Lightweight Process Coordination. Users (product developers and system/software designers) easily develop services and applications by composing reusable building-blocks into (flow-) graph structures that can be animated, analyzed, simulated, verified, executed, and compiled. This way of handling the collaborative design of complex embedded systems has proven to be effective and adequate for the cooperation of non-programmers and non-technical people, which is the focus of this contribution, and it is now being rolled out in the operative practice.

Risk factors associated with multidrug-resistant tuberculosis in Espírito Santo, Brazil

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Geisa Fregona

Full Text Available ABSTRACT OBJECTIVE To analyze the prevalence and factors associated with multidrug-resistant tuberculosis in Espírito Santo, Brazil. METHODS This is a cross-sectional study of cases of tuberculosis tested for first-line drugs (isoniazid, rifampicin, pyrazinamide, ethambutol, and streptomycin in Espírito Santo between 2002 and 2012. We have used laboratory data and registration of cases of tuberculosis – from the Sistema Nacional de Agravos de Notificação and Sistema para Tratamentos Especiais de Tuberculose. Individuals have been classified as resistant and non-resistant and compared in relation to the sociodemographic, clinical, and epidemiological variables. Some variables have been included in a logistic regression model to establish the factors associated with resistance. RESULTS In the study period, 1,669 individuals underwent anti-tuberculosis drug susceptibility testing. Of these individuals, 10.6% showed resistance to any anti-tuberculosis drug. The rate of multidrug resistance observed, that is, to rifampicin and isoniazid, has been 5%. After multiple analysis, we have identified as independent factors associated with resistant tuberculosis: history of previous treatment of tuberculosis [recurrence (OR = 7.72; 95%CI 4.24–14.05 and re-entry after abandonment (OR = 3.91; 95%CI 1.81–8.43], smoking (OR = 3.93; 95%CI 1.98–7.79, and positive culture for Mycobacterium tuberculosis at the time of notification of the case (OR = 3.22; 95%CI 1.15–8.99. CONCLUSIONS The partnership between tuberculosis control programs and health teams working in the network of Primary Health Care needs to be strengthened. This would allow the identification and monitoring of individuals with a history of previous treatment of tuberculosis and smoking. Moreover, the expansion of the offer of the culture of tuberculosis and anti-tuberculosis drug susceptibility testing would provide greater diagnostic capacity for the resistant types in Espírito Santo.

Dialogues between Boaventura de Sousa Santos, Special Education and Curriculum

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Alexandro Braga Vieira

2018-03-01

Full Text Available This study aims to bring together special education and the production by Boaventura de Sousa Santos. It seeks to understand how the author’s theories contributed to the education of children with disabilities, pervasive developmental disorders, and high-potential/giftedness in regular schools. We analyze major concepts of the author’s thoughts and how they can be approached regarding premises of special education from the perspective of school inclusion. Also, we present an experiment of continuing education carried out with elementary education teachers to rethink the implication of school curricula for special education students.

[Haitian migration to Santo Domingo].

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Latortue, P R

1985-01-01

This work examines the history of Haitian migration to the Dominican Republic, the central role of Haitian migration in Dominican society, working conditions of Haitian migrants in the Dominican Republic, and the relationship of the migration to economic development on the island of Hispaniola. Lack of data, the difficulty of measuring illegal movement, and the problem of defining Haitians in Santo Domingo have impeded understanding of migration to the Dominican Republic. It is believed by many authorities that Haitian migration to Santo Domingo is considerable and perhaps exceeds that to the US. Haitian migration to the Dominican Republic began after 1915 with the fall of the Haitian president, a worsening of economic conditions partly caused by stagnation in the agricultural sector, and the newly dominant role of the US in Haitian economic affairs. The Great Depression of the 1930s was a direct antecedent of the massacre of Haitians by Dominican police in which some 30 thousand persons were killed; the economic recession of the early 1980s has also caused an outburst of antiHaitian feeling in the Dominican Republic although 80% of laborers in the sugar industry are Haitians. Sugar is extremely important to the Dominican economy: in 1974, sugar covered 12% of cultivated land, produced 40% of foreign exchange earnings, and was responsable for 21% of taxable income. Dominicans however refuse to work in sugar plantations under the current technological. conditions and wage system. Although the government periodically demands the Dominicanization of the sugar work force, no such changes have been made. Sugar will probably continue to play a decisive role in the generation of foreign exchange despite introduction of more technologically advanced sectors which benefit from better prices in the international market. Possibilities of mechanizing sugar production in the Dominican Republic appear remote, and failure to modernize an important sector of the economy has

Accelerated bridge construction (ABC) decision making and economic modeling tool.

Science.gov (United States)

2011-12-01

In this FHWA-sponsored pool funded study, a set of decision making tools, based on the Analytic Hierarchy Process (AHP) was developed. This tool set is prepared for transportation specialists and decision-makers to determine if ABC is more effective ...

The Value of Green Technology at ABC Community College

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McAllister, Bernadette

2012-01-01

A challenge facing community colleges nationwide is to reduce the carbon footprint of campuses by initiating green technology initiatives. This case study assessed the effect of switching from paper assignments to a learning management system at ABC Community College. The topic is important because federal and state funding, as well as…

The ABC transporter Rv1272c of Mycobacterium tuberculosis enhances the import of long-chain fatty acids in Escherichia coli.

Science.gov (United States)

Martin, Audrey; Daniel, Jaiyanth

2018-02-05

Mycobacterium tuberculosis (Mtb), which causes tuberculosis, is capable of accumulating triacylglycerol (TAG) by utilizing fatty acids from host cells. ATP-binding cassette (ABC) transporters are involved in transport processes in all organisms. Among the classical ABC transporters in Mtb none have been implicated in fatty acid import. Since the transport of fatty acids from the host cell is important for dormancy-associated TAG synthesis in the pathogen, mycobacterial ABC transporter(s) could potentially be involved in this process. Based on sequence identities with a bacterial ABC transporter that mediates fatty acid import for TAG synthesis, we identified Rv1272c, a hitherto uncharacterized ABC-transporter in Mtb that also shows sequence identities with a plant ABC transporter involved in fatty acid transport. We expressed Rv1272c in E. coli and show that it enhances the import of radiolabeled fatty acids. We also show that Rv1272c causes a significant increase in the metabolic incorporation of radiolabeled long-chain fatty acids into cardiolipin, a tetra-acylated phospholipid, and phosphatidylglycerol in E. coli. This is the first report on the function of Rv1272c showing that it displays a long-chain fatty acid transport function. Copyright © 2018 Elsevier Inc. All rights reserved.

A Short Proof of Euler's Inequality R ≥ 2r Theorem. Let ∆ ABC be an ...

Indian Academy of Sciences (India)

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A Short Proof of Euler's Inequality R ≥ 2r. Theorem. Let ∆ ABC be an arbitrary triangle with circumradius R and inradius r. Then R ≥ 2r with equality holding if and only if ∆ABC is equilateral. This was first published by Euler in 1765. Since then several proofs have followed, some geometric and some algebraic. We will use ...

Activity-based Costing (ABC) and Activity-based Management(ABM)Implementation – Is This the Solution for Organizations to Gain Profitability?

OpenAIRE

Ildikó Réka CARDOS; Stefan PETE

2011-01-01

Adherents of ABC/ABM systems claimed traditional management accounting systems generated misleading costs in a contemporary, tumultuous, often changing business environment and implementing ABC/ABM would remedy this. That is why activity-based costing (ABC) and activity-based management (ABM) represents the symbol of improved competitiveness and efficiency in every organization.The purpose of this article – after analyzing the existing literature in the field – is to emphasize that new cost s...

Una encrucijada incierta. Independentismo, anexionismo y abolición de la esclavitud en Santo Domingo, 1809-1821.

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Jose Luis Belmonte Postigo

2015-01-01

Full Text Available La reintegración de Santo Domingo a la Monarquía española tuvo serias dificultades que amenazaron el asentamiento del sistema colonial español. La compleja situación política de la península, y la extensión del movimiento insurgente en los territorios continentales, supusieron obstáculos que imposibilitaron la remisión de los recursos que Santo Domingo demandaba. En mitad del marasmo económico, el auge de las ideas independentistas cobró cada vez mayor relevancia, dando lugar a toda una serie de conspiraciones inspiradas en dos modelos, el caraqueño y el haitiano, que pretendían el establecimiento de un nuevo modelo político y que observaba de manera disímil el mantenimiento de la esclavitud.

A contribuição de Milton Santos para os estudos de ecossistemas das mídias

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Fabio B. Josgrilberg

2015-01-01

Full Text Available El artículo tiene como objetivo presentar posibles aportes del geógrafo brasileño Milton Santos al análisis de los ecosistemas de los medios. El texto busca dialogar con la tradición de los estudios comunicacionales conocidos como ecología de los medios, que es altamente influenciada por nombres como Marshall McLuhan, Neil Postman y Walter Ong. El artículo también se apoya en conceptos y metáforas retiradas de las ciencias de los ecosistemas, y concluye que el principal aporte de Santos al debate está en cómo él articula la cuestión del poder económico y técnico a su análisis del espacio geográfico haciendo uso de abordajes sistémicos y dialécticos.

Mass media, espacio y tiempo en Todos Santos, Baja California Sur

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Rossana Almada

2001-01-01

Full Text Available El artículo que aquí se sintetiza es un primer acercamiento, desde la perspectiva de autores entre los que destaca Manuel Castells, a un proyecto mayor que pretende analizar e interpretar el proceso de transformaciones que ha venido sufriendo el pueblo de Todos Santos, Baja California Sur BCS, debido a la llegada de dos contingentes de inmigrantes: el primero, rocedente de Estados Unidos y Canadá, llegó a comprar las casas del centro del pueblo; algunos con la intención de quedarse e instalar negocios, principalmente de venta de Bienes Raíces, otros, para pasar allí la temporada otoño invierno; y el segundo, traído del interior del país, principalmente de Acayucan Veracruz y de Ocotepec Guerrero como jornaleros agrícolas por una compañía Sinaloense. Esta inmigración ha introducido a Todos Santos dentro de lo que Castells denomina como sociedad red, es decir, dentro de procesos sociales organizados, cada vez más, en torno a redes que constituyen las nuevas formas de organización social. En resumen, el presente trabajo aborda los efectos de la globalización en la transformación de un pueblo sudcaliforniano, a través de la llegada de los inmigrantes arriba mencionados y del uso de los medios de comunicación vía satélite.

Santo Domingo Savio: un territorio reterritorializado

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Jorge Ivu00E1n Ballesteros Toro

2010-01-01

Full Text Available Santo Domingo Savio es un barrio de la Comuna Popular número 1,1 ubicado en el nororiente de la ciudad de Medellín (Antioquia, Colombia. Es un territorio formado a través de la ocupación marginal e ilegal de la tierra, que ha sido marcado por la violencia y la pobreza. El Estado, luego de años de abandono, ha implementado proyectos de desarrollo urbano que han generado infraestructura de transporte, espacio público y educación; proyectos que enmarcan la ciudad en el contexto de la competitividad. La actual dinámica territorial ha convertido esta comuna en un lugar atractivo para residentes y turistas, en un espacio reterritorializado por el Estado; además, ha transformado el lugar en un laboratorio de ciudad y en un modelo de renovación. Bajo este escenario, esta exploración pretende visualizar la territorialidad que en el transcurso del tiempo han tenido los diferentes actores en este espacio.

Review: André du Pisani, Reinhart Kössler, and William A. Lindeke (eds., The Long Aftermath of War: Reconciliation and Transition in Namibia (2010 Buchbesprechung: André du Pisani, Reinhart Kössler und William A. Lindeke (Hrsg., The Long Aftermath of War: Reconciliation and Transition in Namibia (2010

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Dag Henrichsen

2011-01-01

Full Text Available Review of the edited volume: André du Pisani, Reinhart Kössler, and William A. Lindeke (eds., The Long Aftermath of War: Reconciliation and Transition in Namibia (Freiburger Beiträge zu Entwicklung und Politik, 37, Freiburg: Arnold-Bergstraesser-Institut, 2010, ISBN 978-3-928597-55-5, 437 pp.Besprechung des Sammelbandes: André du Pisani, Reinhart Kössler und William A. Lindeke (Hrsg., The Long Aftermath of War: Reconciliation and Transition in Namibia (Freiburger Beiträge zu Entwicklung und Politik, 37, Freiburg: Arnold-Bergstraesser-Institut, 2010, ISBN 978-3-928597-55-5, 437 Seiten

Metal and trace element sediment assessment from two estuarine systems: Santos/Sao Vicente and Cananeia, State of Sao Paulo, Brazil; Avaliacao da concentracao de metais e outros elementos de interesse em amostras de sedimentos dos estuarios de Santos/Sao Vicente e Cananeia, estado de Sao Paulo, Brasil

Energy Technology Data Exchange (ETDEWEB)

Amorim, Eduardo Paulo de

2012-07-01

This study evaluated some toxic metals such as Cd, Hg and Pb and some other major and trace elements in surface sediment samples, from two different systems under different degrees of anthropogenic actions: the estuarine system of Santos/Sao Vicente and the southern part of the Cananeia estuary, both on the Sao Paulo state coast. Sediment samples were collected in 16 stations in the Santos/Sao Vicente estuary and 13 stations in the Cananeia estuary, during summer and winter of 2005 and 2006, in both estuaries. Three analytical techniques were used: NAA, AAS and ICP OES. NAA was used for the quantification of major element concentration levels (Ca, Fe and Na), trace elements (As, Ba, Br, Cd, Co, Cu, Cr, Cs, Hf, Rb, Sb, Sc, Se, Ta, Th, U, and Zn and rare earths elements La, Ce, Eu, Nd, Sm, Lu, Tb, Yb). ICP OES was used for determination of the concentration levels of Al, Ba, Be, Bi, B, Cd, Co, Pb, Cu, Cr, Sn, Sr, Fe, Li, Mn, Mo, Ni, Tl, Ti, V and Zn. AAS for Cd and Pb quantification through graphite furnace (GF AAS) and Hg through cold vapor generation (CV AAS). Methodology validation according to precision and accuracy was performed by reference material analyses for the three analytical techniques used. Detection and quantification limits were calculated for each element evaluated. Seasonal variations (summer and winter), spatial and temporal (2005 e 2006) variations of metals and trace elements were also evaluated. In the Santos estuary, in general, metal and trace element concentrations , organic matter content and % of pelitic fraction found in the Santos channel (area 1) were higher than those of the Santos Bay (area 2) and Sao Vicente channel (area 3). Area 1 suffers high impact from industrial activities from the Cubatao region and Santos port. The sediments from station 14 (area 3, Sao Vicente channel), showed the same behavior of those from area 1, suffering influence from the industrial pole and located in a mangrove area. In comparison with TEL and PEL

IMPLEMENTATION OF THE ABC COSTING IN A SERVICES PROVIDER COMPANY

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Luiz Ricardo Aguena Jacintho Gil de Castro

2012-12-01

Full Text Available This paper describes the implementation of the Activity-Based Cost (ABC method in a company of taxes and accounting services and outlines the positive and negative aspects encountered during implementation. It should be taken into account that this work has been developed in the fiscal area of cost verification. Bibliographical references, internal company documents and interviews with industry officials and the administrator responsible for the company were used. In the evolving of operations, the costs of the fiscal area and their main activities have been described monthly and through this information, drivers have been developed and the ABC (Activity-Based Costing method has been adopted. With the implementation it became clear that the system provides better visualization for the decision making process, it also provided learning for the company, so that the method should be used for an undetermined period of time.

A RELIGIOSIDADE POPULAR NOS EXERCÍCIOS ESPIRITUAIS DE SANTO INÁCIO DE LOYOLA

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Victor Codina

1987-01-01

Full Text Available Uma primeira impressão frente ao texto e à prática dos Exercícios Espirituais de Santo Inácio (EE nos levaria à conclusão de que os EE se dirigem prioritariamente aos setores não populares da sociedade e da Igreja, e que tanto seu conteúdo como sua estrutura respondem a uma espiritualidade culta e quase elitista.

Mass media, espacio y tiempo en Todos Santos, Baja California Sur

OpenAIRE

Rossana Almada

2001-01-01

El artículo que aquí se sintetiza es un primer acercamiento, desde la perspectiva de autores entre los que destaca Manuel Castells, a un proyecto mayor que pretende analizar e interpretar el proceso de transformaciones que ha venido sufriendo el pueblo de Todos Santos, Baja California Sur BCS, debido a la llegada de dos contingentes de inmigrantes: el primero, rocedente de Estados Unidos y Canadá, llegó a comprar las casas del centro del pueblo; algunos con la intención de quedarse e inst...

Starting with ABC and Finishing with XYZ: What Financial Reporting Model Best Fits a Faculty and Why?

Science.gov (United States)

Berry, Prudence Jane

2014-01-01

This article looks at the range of financial reporting models available for use in the Australian higher education sector, the possible application of activity-based costing (ABC) in faculties and the eventual rejection of ABC in favour of a more qualitative model designed specifically for use in one institution, in a particular Faculty. The…

Comparing serial and nonserial sexual offenders: alcohol and street drug consumption, impulsiveness and history of sexual abuse Comparando agressores sexuais seriais e não seriais: consumo de álcool e outras drogas, impulsividade e história de abuso sexual

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Danilo Antonio Baltieri

2008-03-01

Full Text Available OBJECTIVE: To evaluate the differences between serial and nonserial sexual offenders in terms of alcohol and drug consumption, impulsivity, and personal history of being sexually abused. METHOD: A sectional and retrospective study carried out by the team of the outpatient clinic for the treatment of sexual disorders at Faculdade de Medicina do ABC - Santo André, Brazil. Three groups of subjects (n = 198 consisting of sexual offenders against one victim, two victims and three or more victims were examined. Convicts sentenced only for sexual crimes were evaluated with the Drug Addiction Screening Test, the CAGE, the Short Alcohol Dependence Data, the Barratt Impulsiveness Scale, the Sexual Addiction Screening Test, and the Static-99. RESULTS: Sexual offenders against three or more victims showed more frequent history of being sexually abused than the sexual offenders against one victim. A one-way analysis of variance indicated that sexual offenders against three or more victims evidenced significantly higher scores on the Barratt Impulsiveness Scale and on the Sexual Addiction Screening Test than did the sexual aggressors against one victim. After a multinomial logistic regression analysis, the Barratt Impulsiveness Scale and the history of being sexually abused were predicting factors for the group of aggressors against three or more victims in relation to the aggressors against one victim. CONCLUSIONS: Sexual offenders against three or more victims present different characteristics from other groups of sexual offenders and these findings can help to create proposals for the management of this type of inmates.OBJETIVO: Avaliar diferenças entre agressores sexuais seriais e não seriais em termos de consumo de álcool e de outras drogas, impulsividade e história pessoal de abuso sexual. MÉTODO: Trata-se de estudo transversal e retrospectivo realizado pelo Ambulatório de Transtornos da Sexualidade da Disciplina de Psiquiatria da Faculdade de

Describing the role of Drosophila melanogaster ABC transporters in insecticide biology using CRISPR-Cas9 knockouts.

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Denecke, Shane; Fusetto, Roberto; Batterham, Philip

2017-12-01

ABC transporters have a well-established role in drug resistance, effluxing xenobiotics from cells and tissues within the organism. More recently, research has been dedicated to understanding the role insect ABC transporters play in insecticide toxicity, but progress in understanding the contribution of specific transporters has been hampered by the lack of functional genetic tools. Here, we report knockouts of three Drosophila melanogaster ABC transporter genes, Mdr49, Mdr50, and Mdr65, that are homologous to the well-studied mammalian ABCB1 (P-glycoprotein). Each knockout mutant was created in the same wild type background and tested against a panel of insecticides representing different chemical classes. Mdr65 knockouts were more susceptible to all neuroactive insecticides tested, but Mdr49 and Mdr50 knockouts showed increased susceptibility or resistance depending on the insecticide used. Mdr65 was chosen for further analysis. Calculation of LC 50 values for the Mdr65 knockout allowed the substrate specificity of this transporter to be examined. No obvious distinguishing structural features were shared among MDR65 substrates. A role for Mdr65 in insecticide transport was confirmed by testing the capacity of the knockout to synergize with the ABC inhibitor verapamil and by measuring the levels of insecticide retained in the body of knockout flies. These data unambiguously establish the influence of ABC transporters on the capacity of wild type D. melanogaster to tolerate insecticide exposure and suggest that both tissue and substrate specificity underpin this capacity. Copyright © 2017 Elsevier Ltd. All rights reserved.

Papagaio-de-peito-roxo Amazona vinacea (Kuhl (Aves: Psittacidae no norte do Espírito Santo: redescoberta e conservação Vinaceous Amazon Amazona vinacea (Kuhl (Aves: Psittacidae in the northern region of Espirito Santo state, southeastern Brazil: rediscovery and conservation

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Lucas A. Carrara

2008-03-01

Full Text Available Amazona vinacea (Kuhl, 1820 é uma espécie endêmica da Mata Atlântica e ameaçada de extinção no Brasil e no mundo. Não existem relatos recentes de sua presença na porção setentrional de sua distribuição ao norte do estado do Rio de Janeiro. O último é datado provavelmente de 1991, tendo sido considerado extinto ao norte do Espírito Santo. O presente trabalho noticia a redescoberta da espécie em Alto Rio Novo, noroeste do Espírito Santo, divisa com Minas Gerais. Foram registrados bandos em duas localidades em dezembro de 2005, sendo o maior deles composto por 28 indivíduos. Durante os registros foi observado A. vinacea se alimentando de Anadenanthera sp. (Fabaceae: Mimosoideae, uma nova fonte alimentar para a espécie. Os registros históricos mais recentes para a região citam localidades com distância inferior a 35 km dos atuais registros, reforçando a importância local. No entanto, a degradação ambiental e a captura ilegal representam obstáculos à conservação da espécie nesta região. Em dezembro de 2002 foi criado o Parque Nacional dos Pontões Capixabas, primeira Unidade de Conservação na porção serrana do norte do Espírito Santo. Uma das áreas históricas da espécie está incluída em seus limites e um dos locais onde foi agora redescoberto fica a cerca de 10 km de distância da borda do parque. Essa Unidade de Conservação é essencial à proteção de trechos nativos da Mata Atlântica e conseqüentemente do papagaio-de-peito-roxo. Além de medidas conservacionistas, a aquisição de informações sobre as populações de A. vinacea no noroeste do Espírito Santo e leste de Minas Gerais torna-se indispensável para a proposição de medidas de manejo capazes de reverter o grave quadro atual, objetivando viabilizar a permanência de populações na região mais setentrional da distribuição conhecida atualmente para a espécie.Endemic of the Atlantic Forest, Amazona vinacea (Kuhl, 1820 is listed as

Molecular characterization of ABC transporters in marine ciliate, Euplotes crassus: Identification and response to cadmium and benzo[a]pyrene.

Science.gov (United States)

Kim, Hokyun; Yim, Bora; Kim, Jisoo; Kim, Haeyeon; Lee, Young-Mi

2017-11-30

ATP-binding cassette (ABC) transporters participate in transporting various substances, including xenobiotics, in or out of cells. However, their genetic information and function in ciliates remain still unclear. In this study, we sequenced and characterized two ABC transporter genes (EcABCB and EcABCC), and investigated the effect of cadmium (Cd) and benzo[a]pyrene (B[a]P) on their function and gene expression, using efflux assay and real-time reverse transcription-polymerase chain reaction (qRT-PCR), respectively, in the marine ciliate, Euplotes crassus. Sequencing analysis and efflux assay showed that EcABCB and EcABCC are typical ABC transporters, possessing conserved function. Exposure to Cd (≥5mg/L) and B[a]P (≥50.5μg/L) enhanced accumulation of a substrate. A significant increase in the expression of EcABCB and EcABC mRNA was observed at lower concentration in response to Cd and B[a]P. Our findings indicate that Cd and B[a]P could inhibit the efflux function of ABC transporters, leading to cellular toxicity in the ciliate. Copyright © 2017 Elsevier Ltd. All rights reserved.

Alzheimer's and ABC transporters--new opportunities for diagnostics and treatment.

Science.gov (United States)

Pahnke, Jens; Langer, Oliver; Krohn, Markus

2014-12-01

Much has been said about the increasing number of demented patients and the main risk factor 'age'. Frustratingly, we do not know the precise pattern and all modulating factors that provoke the pathologic changes in the brains of affected elderly. We have to diagnose early to be able to stop the progression of diseases that irreversibly destroy brain substance. Familiar AD cases have mislead some researchers for almost 20 years, which has unfortunately narrowed the scientific understanding and has, thus, lead to insufficient funding of independent approaches. Therefore, basic researchers hardly have been able to develop causative treatments and clinicians still do not have access to prognostic and early diagnostic tools. During the recent years it became clear that insufficient Aβ export, physiologically facilitated by the ABC transporter superfamily at the brain's barriers, plays a fundamental role in disease initiation and progression. Furthermore, export mechanisms that are deficient in affected elderly are new targets for activation and, thus, treatment, but ideally also for prevention. In sporadic AD disturbed clearance of β-amyloid from the brain is so far the most important factor for its accumulation in the parenchyma and vessel walls. Here, we review findings about the contribution of ABC transporters and of the perivascular drainage/glymphatic system on β-amyloid clearance. We highlight their potential value for innovative early diagnostics using PET and describe recently described, effective ABC transporter-targeting agents as potential causative treatment for neurodegenerative proteopathies/dementias. Copyright © 2014 Elsevier Inc. All rights reserved.

Educação sanitária e medicina preventiva Health education and preventive medicine

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Bruna Maria Lucchesi

1969-06-01

Full Text Available Foram apresentados programas de atividades educativas, sanitárias e cursos desenvolvidos desde setembro de 1967, com o fito de melhorar os padrões de saúde e alimentação de parte da população do município de Santo André, São Paulo. Os cursos têm sido ministrados às normalistas e às mães de instrução primária, residentes em zonas afastadas do Centro urbano. As alunas dos Cursos já estão pondo em prática os ensinamentos recebidos, divulgando conhecimentos de Educação Sanitária, de Agricultura e de Educação Alimentar em todos os Estabelecimentos de Ensino primário de Santo André, num total de 80 unidades com 54.000 alunos matriculados. Conclui-se que através de cursos dessa natureza é possível conseguir a participação de uma população para sanar possíveis problemas advindos da falta de conhecimento de medidas de saneamento, práticas agrícolas e de uma alimentação bem orientada. Trabalhos desta natureza só são votados a êxito quando houver participação conjunta de elementos técnicos dos setôres administrativos municipais, estaduais, federais, particulares e da própria comunidade trabalhada.This work will be accomplished through educational and sanitary activities, and courses developed since September 1967, with the purpose of improving health and nourishment standards. These courses are being given to 2nd and 3rd grades from "Escolas Normais", and to mothers of primary educational level, who live in the suburbs. More advanced students, in the 1st grade of high-school are already applying the education received, about Health Education, Agriculture, and Food Education in all primary schools establishments in Santo André (80 units with 54000 students. We conclude, by stating that attending courses of this sort, it is possible, to obtain participation of the population, in preventing problems which may arise from the lack of knowledge on sanitation, agricultural practices and well oriented nourshment

``Planetário e Teatro Digital Johannes Kepler'' and its Institutional Pedagogical Project

Science.gov (United States)

Faria, R. Z.; Calil, M. R.; Perez, E. R.; Kanashiro, M.; Silva, L. C. P.; Calipo, F.

2014-10-01

This work relates the reception of schools, started on August 2012, in the astronomic laboratory of the "Planetário e Teatro Digital Johannes Kepler", located in the "Sabina - Escola Parque do Conhecimento" in Santo André, São Paulo. The idealization of this project, authorship of Marcos Calil, PhD, consists in four apprenticeship environments disposed around the planetary dome. They make reference to the System Sun - Earth - Moon (Tellurium), Solar System, Astronautic and Stars. On Tuesdays and Wednesdays the astronomic laboratory is used by Santo André municipal schools for focused lessons, being possible on Thursdays scheduling for private and public schools. On weekends and holidays is opened for the visitors. Since the inauguration to the beginning of activities with students, the monitor team was guided and trained on contents of Astronomy and Aeronautic to execute the schools service. This is done in four stages, which are: reception, course trough the astronomic laboratory, dome session and activities closure. During the reception the acquaintance rules are passed on for a better visit. Before starting the course the monitors do a survey about the previous knowledge of the students. On the astronomic laboratory resources of the environment are used to explain the contents of Astronomy and Astronautic, always considering the age group and the curriculum developed in classroom. After the course the students watch a planetary session supporting the contents seen on the astronomic laboratory. At the end a feedback is done with the students about the subject discussed. During the visit the teachers fulfill an evaluation about the place and the service. From August 2012 to November 2012 were attended between municipal, public and private schools. From the 4932 students attended, 92% belonged to the municipal network, 5% to the private network and 3% to the public network. From the 189 evaluations done by the teachers, 97.8% were satisfied, 2.1% partially

aprABC: A Mycobacterium tuberculosis complex-specific locus that modulates pH-driven adaptation to the macrophage phagosome

Science.gov (United States)

Abramovitch, Robert B.; Rohde, Kyle H.; Hsu, Fong-Fu; Russell, David G.

2011-01-01

Summary Following phagocytosis by macrophages, Mycobacterium tuberculosis (Mtb) senses the intracellular environment and remodels its gene expression for growth in the phagosome. We have identified an Acid and Phagosome Regulated (aprABC) locus that is unique to the Mtb complex and whose gene expression is induced during growth in acidic environments in vitro and in macrophages. Using the aprA promoter, we generated a strain that exhibits high levels of inducible fluorescence in response to growth in acidic medium in vitro and in macrophages. aprABC expression is dependent on the two-component regulator phoPR, linking phoPR signaling to pH sensing. Deletion of the aprABC locus causes defects in gene expression that impact aggregation, intracellular growth, and the relative levels of storage and cell wall lipids. We propose a model where phoPR senses the acidic pH of the phagosome and induces aprABC expression to fine-tune processes unique for intracellular adaptation of Mtb complex bacteria. PMID:21401735

Esimene Eesti maja Hiinas = The first Estonian house in China / Andres Põime, Lauri Vaimel ; interv. Triin Ojari

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Põime, Andres

2008-01-01

Vestlus Pekingi Eesti saatkonna arhitektuurikonkursi võidutöö autoritega. Tulemused: I preemia - Andres Põime, Lauri Vaimel, II - Erik Nobel, Christian Jensen, Kristen Herup Sovang, Soren Andersson, Pille Kivihall, Dan Ljungar, Hans Willadsen (Taani), III - Kalle Vellevoog, Velle Kadalipp, Tiiu Truus, Martin Prommik

Quantitative Assessment of the Association between ABC Polymorphisms and Osteosarcoma Response: a Meta-analysis.

Science.gov (United States)

Chen, Xu; Jiang, Min; Zhao, Rui-Ke; Gu, Guo-Hao

2015-01-01

ABC proteins are one key type of transport superfamilies which undertake majority of drug transport, which affect the osteosarcoma response to chemotherapeutics. Previous studies have suggested the association between ABC polymorphisms and osteosarcoma response. However, the results of previous studies remain controversial. Therefore, we perform a meta-analysis to get a more precise estimation of this association. The association between ABC polymorphisms and osteosarcoma response was assessed by odds ratios (ORs) together with their 95% confidence intervals (CIs). Three polymorphisms of ABC including ABCB1 rs1128503, ABCC3 rs4148416 and ABCC2 rs717620 polymorphism were investigated. Overall, significant association was observed between ABCC3 rs4148416 polymorphism and osteosarcoma response under allele contrast (T vs. C: OR=1.73, 95%CI=1.09-2.74, P=0.019), homozygote comparison (TT vs. CC: OR=2.00, 95%CI=1.25-3.23, P=0.004), recessive genetic model (TT vs. OR=1.80, 95%CI=1.14-2.84, P=0.011) and dominant genetic model (TT/TC vs. CC: OR=1.70, 95%CI=1.20-2.42, P=0.003). Moreover, significant association was also observed in Caucasian population rather than Asian population for ABCB1 rs1128503 polymorphism. We conclude that ABCC3 rs4148416 polymorphism was significantly associated with poor osteosarcoma response and ABCB1 rs1128503 polymorphism was significantly associated with good osteosarcoma response in Caucasian population rather than Asian population.

O Santo do Bispo

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Beatriz Catão Cruz Santos

Full Text Available O artigo propõe uma biografia de D. José Antonio de Guadalupe, bispo do Rio de Janeiro entre 1725 e 1740, a partir da análise de diversos documentos, sobretudo os seus escritos pastorais. Estes são considerados não só práticas religiosas, mas um gênero literário adequado a um conjunto de procedimentos e convenções previstos para sua leitura e recepção. Através da reconstrução da trajetória daquele agente, pretende-se destacar como sua ação e memória contribuem para a devoção de São Gonçalo de Amarante e conformação das práticas católicas no Rio de Janeiro e regiões circunvizinhas por diferentes grupos sociais. Objetiva-se, também, pôr em evidência a devoção e festa de São Gonçalo, discutindo a relação entre a hierarquia católica e os devotos pardos do santo, reunidos numa irmandade situada na Vila de São Sebastião, em São Paulo do século XIX. A análise do Compromisso da Irmandade de São Gonçalo aponta para as formas e modalidades da crença católica na sociedade colonial.

ABC- and SLC-Transporters in Murine and Bovine Mammary Epithelium

DEFF Research Database (Denmark)

Yagdiran, Yagmur; Oskarsson, Agneta; Knight, Christopher H.

2016-01-01

Some chemicals are ligands to efflux transporters which may result in high concentrations in milk. Limited knowledge is available on the influence of maternal exposure to chemicals on the expression and function of transporters in the lactating mammary gland. We determined gene expression of ABC ...

ABC transporters from Botrytis cinerea in biotic and abiotic interactions

NARCIS (Netherlands)

Schoonbeek, H.

2004-01-01

Botrytis cinereais the causal agent of grey mould disease on a wide variety of crop plants. It is relatively insensitive to natural and synthetic fungitoxic compounds. This thesis describes how ABC (ATP-binding cassette) transporters contribute to protection by actively

Agrochemical characterization of vermicomposts produced from residues of Palo Santo (Bursera graveolens) essential oil extraction.

Science.gov (United States)

Carrión-Paladines, Vinicio; Fries, Andreas; Gómez-Muñoz, Beatriz; García-Ruiz, Roberto

2016-12-01

Fruits of Palo Santo (Bursera graveolens) are used for essential oil extraction. The extraction process is very efficient, because up to 3% of the fresh fruits can be transformed into essential oil; however, a considerable amount of waste is concurrently produced (>97% of the fresh biomass). Recent developments in Ecuadorian policies to foster environmentally friendly agroforestry and industrial practices have led to widespread interest in reusing the waste. This study evaluated the application of four vermicomposts (VMs), which are produced from the waste of the Palo Santo fruit distillation in combination with other raw materials (kitchen leftovers, pig manure, goat manure, and King Grass), for agrochemical use and for carbon (C) and nitrogen (N) decomposition in two soils with different textures. The results showed that the vermicompost mixtures (VMM) were valuable for agricultural utilisation, because total N (min. 2.63%) was relatively high and the C/N ratio (max. 13.3), as well as the lignin (max. 3.8%) and polyphenol (max. 1.6%) contents were low. In addition, N availability increased for both soil types after the application of the VMM. In contrast, N became immobile during decomposition if the VM of the pure waste was added. This likely occurred because of the relatively low total N (1.16%) content and high C/N ratio (35.0). However, the comparatively low C decomposition of this VM type makes its application highly recommendable as a strategy to increase the levels of organic matter and C, as well as for soil reclamation. Overall, these results suggest that the residues of the Palo Santo essential oil extraction are a potential source for vermicompost production and sustainable agriculture. Copyright © 2016 Elsevier Ltd. All rights reserved.

Utilização dos Centros de Atenção Psicossocial (CAPS na cidade de Santos, São Paulo, Brasil Utilization of community mental health services in the city of Santos, São Paulo, Brazil

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Sérgio Baxter Andreoli

2004-06-01

Full Text Available A fim de descrever a clientela atendida nos Centros de Atenção Psicossocial (CAPS da Cidade de Santos foi realizado um censo de pacientes atendidos nos CAPS no período 1º de junho de 2001 a 30 de junho de 2001. O primeiro contato do paciente com o serviço foi registrado e seus dados foram preenchidos em ficha padronizada utilizando o prontuário médico como fonte de informação. Foram atendidos 1.673 usuários, com idade média de 46 anos, mulheres (59,0%, morando com a família (78,0% e tempo médio de três anos em tratamento no serviço. Atenderam 38,0% de esquizofrênicos, esquizotípicos e delirantes, 31,0% com transtorno de humor e 17,0% de neuróticos, nas modalidades de ambulatório médico-psiquiátrico (81,0%, individual (23,0%, grupal (13,0% e reabilitação psicossocial (4,3%. Os CAPS de Santos atendem todas as categorias de transtornos mentais, sendo os mais freqüentes aqueles considerados mais graves, o que é esperado para este tipo de serviço. O modelo de tratamento oferecido tem características ambulatorial e médico-psiquiátrica.To report on the clientele treated at community mental health services (CAPS in the city of Santos, São Paulo, Brazil, a census was conducted of the patients examined at the services from June 1, 2001, to June 30, 2001. The patient's initial contact with the service was registered, and data were recorded on a standardized form, using the medical case history as a source of information. Among the 1,673 patients, average age was 46 years, 59.0% were female, 58.0% lived with their families, and mean duration of treatment was three years. Some 38.0% were schizophrenic, schizotypical, or in acute delusional states, 31.0% presented mood disorders, and 17.0% were neurotic. Treatment modalities included out-patient psychiatric (81.0%, individual (23.0%, group (13.0%, and psychosocial rehabilitation (4.3%. In Santos, CAPS treat all categories of mental disorders (and frequently those considered the

SOME IMPORTANT FACTORS AFFECTING EVOLUTION OF ACTIVITY BASED COSTING (ABC) SYSTEM IN EGYPTIAN MANUFACTURING FIRMS

OpenAIRE

Karim MAMDOUH ABBAS

2014-01-01

The present investigation aims to determine the factors affecting evolution of Activity Based Costing (ABC) system in Egyptian case. The study used the survey method to describe and analyze these factors in some Egyptian firms. The population of the study is Egyptian manufacturing firms. Accordingly, the number of received questionnaires was 392 (23 Egyptian manufacturing firms) in the first half of 2013. Finally, the study stated some influencing factors for evolution this system (ABC) in Eg...

ABC and VED Analysis of the Pharmacy Store of a Tertiary Care Teaching, Research and Referral Healthcare Institute of India.

Science.gov (United States)

Devnani, M; Gupta, Ak; Nigah, R

2010-04-01

The ABC and VED (vital, essential, desirable) analysis of the pharmacy store of Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India, was conducted to identify the categories of items needing stringent management control. The annual consumption and expenditure incurred on each item of pharmacy for the year 2007-08 was analyzed and inventory control techniques, i.e. ABC, VED and ABC-VED matrix analysis, were applied. The drug formulary of the pharmacy consisted of 421 items. The total annual drug expenditure (ADE) on items issued in 2007-08 was Rs. 40,012,612. ABC analysis revealed 13.78%, 21.85% and 64.37% items as A, B and C category items, respectively, accounting for 69.97%, 19.95% and 10.08% of ADE of the pharmacy. VED analysis showed 12.11%, 59.38% and 28.51% items as V, E, and D category items, respectively, accounting for 17.14%, 72.38% and 10.48% of ADE of the pharmacy. On ABC-VED matrix analysis, 22.09%, 54.63% and 23.28% items were found to be category I, II and III items, respectively, accounting for 74.21%, 22.23% and 3.56% of ADE of the pharmacy. The ABC and VED techniques need to be adopted as a routine practice for optimal use of resources and elimination of out-of-stock situations in the hospital pharmacy.

Ehitatud võrdsus. Tüüpprojekteerimine 20. sajandi elamuehituses : 23. september - 29. oktoober, Eesti Arhitektuurimuuseum, Rotermanni soolaladu / Andres Kurg

Index Scriptorium Estoniae

Kurg, Andres, 1975-

2000-01-01

Näitus keskendub linnakorteritele ja -elamutele Eestis, alates 1920. aastate riikliku ehituslaenuga ehitatud korteritest, lõpetades nõukogude perioodi industriaalse massehitusega. Kuraator Andres Kurg, kujundaja arhitektuuribüroo Kolm Pluss Üks

Séminaire de probabilités XXXIX in memoriam Paul-André Meyer

CERN Document Server

Yor, Marc

2006-01-01

The 39th volume of Séminaire de Probabilités is a tribute to the memory of Paul André Meyer. His life and achievements are recalled; homages are rendered by his friends and colleagues. This volume also contains mathematical contributions to classical and quantum stochastic calculus, the theory of processes, martingales and their applications to mathematical finance, Brownian motion. They provide an overview on the current trends of stochastic calculus.

Freshwater gastropods in the Northern littoral mesoregion of Espírito Santo, Brazil

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Marco Antônio Andrade de Souza

2017-09-01

Full Text Available Studies on the distribution of molluscs in Brazilhave been conducted since the beginning of the twentieth and the knowledge of the species distributed in the country represent important findings, which contribute to the understanding of human diseases and those of veterinary importance, transmitted by them. In order to verify the distribution of freshwater gastropods in Espírito Santo, a malacological surveywas carried out in nine municipalities that comprise the Northern mesoregion of the State, between January 2010 and February 2015. Initially the water collections occurring in the municipality were verified and the lotic systems at different levels of use and conservation were determined. Molluscs were collected monthly using a hand net adapted to a stick steel. An individual sample effort of 30 minutes was applied, by scanning, at about ten meters in each one of the selected habitats. A total of 6,000 specimens were collected, represented by genera Melanoides, Drepanotrema, Physa, Biomphalaria and Pomacea. Among the molluscs, some specimens were positive for flatworm larvae of medical and veterinary importance. The results contributed to the knowledge of the current distribution of freshwater gastropods in the Northern region of Espírito Santo whose the only record for the region dates back to 1983.

Downregulation of miR-29a/b/c in placenta accreta inhibits apoptosis of implantation site intermediate trophoblast cells by targeting MCL1.

Science.gov (United States)

Gu, Yongzhong; Bian, Yuehong; Xu, Xiaofei; Wang, Xietong; Zuo, Changting; Meng, Jinlai; Li, Hongyan; Zhao, Shigang; Ning, Yunnan; Cao, Yongzhi; Huang, Tao; Yan, Junhao; Chen, Zi-Jiang

2016-12-01

Placenta accreta is defined as abnormal adhesion of placental villi to the uterine myometrium. Although this condition has become more common as a result of the increasing rate of cesarean sections, the underlying causative mechanism(s) remain elusive. Because microRNA-29a/b/c (miR-29a/b/c) have been shown to play important roles in placental development, this study evaluated the roles of these microRNAs in placenta accreta. Expression of miR-29a/b/c and myeloid cell leukemia-1 (MCL1) were quantified in patient tissues and HTR8/SVneo trophoblast cells using the real-time quantitative polymerase chain reaction. Western blotting was used to analyze expression of the MCL1 protein in HTR8/SVneo trophoblast cells with altered expression of miR-29a/b/c. To determine their role in apoptosis, miR-29a/b/c were overexpressed in HTR-8/SVneo cells, and levels of apoptosis were analyzed by flow cytometry. Luciferase activity assays were used to determine whether MCL1 is a target gene of miR-29a/b/c. Expression of miR-29a/b/c was significantly lower in creta sites compared to noncreta sites (p = 0.018, 0.041, and 0.022, respectively), but expression of MCL1 was upregulated in creta sites (p = 0.039). MCL1 expression was significantly downregulated in HTR-8/SVneo cells overexpressing miR-29a/b/c (p = 0.002, 0.008, and 0.013, respectively). Luciferase activity assays revealed that miR-29a/b/c directly target the 3' untranslated region of MCL1 in 293T cells. Over-expression of miR-29a/b/c induced apoptosis in the HTR-8/SVneo trophoblast cell line. Moreover, histopathological evaluation revealed that the number of implantation site intermediate trophoblast (ISIT) cells was increased in creta sites and that these cells were positive for MCL1. Our results demonstrate that in placenta accreta, miR-29a/b/c inhibits apoptosis of ISIT cells by targeting MCL1. These findings provide new insights into the pathogenesis of placenta accreta. Copyright © 2016 Elsevier Ltd. All rights

Evaluation of the natural radioactivity at sands of anomalous regions of Espirito Santo state, Brazil; Avaliacao da radioatividade natural em areias de regioes anomalas do Espirito Santo, Brasil

Energy Technology Data Exchange (ETDEWEB)

Aquino, Reginaldo Ribeiro de; Pecequilo, Brigitte Roxana Soreanu, E-mail: raquino@ipen.b, E-mail: brigitte@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

2011-10-26

The natural radioactivity in sands of anomalous regions of the state of Espirito Santo, Brazil, were calculated from the concentration of activity of {sup 40}K, {sup 225}Ra and {sup 232}Th for the places of south and central of Camburi, Curva da Jurema, Ilha do Boi, Setibinha, south and central area of Praia da Areia Preta, denominated Black Spot. The samples were sealed and measured by high resolution gamma spectrometry and after a expectation time pf 30 days, until to reach a radioactive equilibrium

Espiritu Santo, Vanuatu Stable Isotope (delta 18O, delta 13C) Data for 1806 to 1979

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Site: Espiritu Santo Island, Vanuatu, 15S, 167E. 173 year record of d18O and d13C. Variable names: QSR Age, QSR 13C, QSR 18O, GRL Age, GRL Qtrly 13C, GRL Qtrly 18O,...

IN SITU density measurements oozy bottom of the access channel to the port of Santos, Sao Paulo, Brazil; Medicoes de densidade IN SITU em fundo vasoso do canal de acesso ao Porto de Santos/SP

Energy Technology Data Exchange (ETDEWEB)

Minardi, P S.P.

1988-09-01

The density of the bottom sediment of the access channel to the port of Santos, Sao Paulo, Brazil was measured. The in situ measurements aimed at verifying the use for navigation purposes of the layers with densities equal to or smaller than 1200 kg/m{sup 3}. (F.E.). 3 refs, 55 figs, 3 tabs.