Tõeline Crocodile Dundee / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

4. sept. hukkus veealuse dokfilmi võtetel Austraalia loodusuurija, loomakaitsja, telekanali Animal Planet sarja "Krokodillikütt" ("Crocodile Hunter") populaarne autor ja esineja Steve Irwin (1962-2006)

Almodovari esimesed katsetused / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

Pedro Almodovarile tehti ettepanek restaureerida oma esimesi eksperimentaalseid katsetusi "Kaks hoora / Armastuslugu, mis lõpeb pulmadega" (1974), "Seks tuleb, seks läheb" (1977), Soodoma lõpp (1979)

Vabaduse tuuled Ungarist / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

Sõpruse kinos algab homme filmiprogramm "Vabaduse tuuled" Ungari 1956.a. ülestõusule pühendatud mängufilmide programm (6 ungari filmi aastaist 1965-2004) : Ungari Instituudi, kino "Sõprus" ja PÖFFi koostööprojekt

Veebruarikuus 2000 lahkunuid / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2000-01-01

Surid : Autant-Lara, Claude prantsuse režissöör (5.08.1903-5.02.2000), Vadim, Roger ukraina päritolu prantsuse režissöör (26.01.1928-11.02.2000), Kedrova, Lila vene päritolu prantsuse näitlejanna (1918-16.02.2000), Martelli, Otello itaalia filmioperaator (19.05.1903-20.02.2000)

Feodaalne verepulm teleekraanil / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2011-01-01

Alates 8. septembrist Fox Life'i eestikeelsel kanalil jooksma hakkavast George R. R. Martini raamatul põhinevast USA telekanali HBO telesarjast "Troonide mäng" (sarja loojad David Benioff ja Dan Weiss)

Kõik algas tinapanekuga saunas / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2007-01-01

Eldar Rjazanov ja tema aastavahetuse menufilmid. "Saatuse iroonia ehk Hüva leili!" (1975) järjefilm "Saatuse iroonia: lugu läheb edasi" ("Ironija sudbõ. Prodolzhenije") : režissöör Timur Bekmambetov : Venemaa 2007

Lugu, milles puuduvad kangelased / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2001-01-01

W.M. Thackeray (1811-1863) romaani "Edevuse laat" ekraniseeringutest. Lähemalt Suurbritannias 1998. aastal valminud 6-osalisest teleseriaalist ja selle kesksetest osatäitjatest. Ka : Teleleht nr. 6, lk. 36-38

Ise kaklevad, ise lepivad / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2001-01-01

Mängufilm "Kes kardab Virginia Woolfi?" ("Who's Afraid Of Virginia Woolf?") : stsenarist Ernest Lehman Edward Albee näidendi järgi : režissöör Mike Nichols : Ameerika Ühendriigid 1966. Ka : Teleleht nr. 11, lk.4

Aare Toikka näidend tuli lavale Budapestis

Index Scriptorium Estoniae

2011-01-01

Budapestis Kolibri teatris esietendus noortelavastus "Help", mille kirjutasid VAT teatri kunstiline juht Aare Toikka ja Ungari lavastja, proosa- ja näitekirjanik Peter Horvath. VAT teatri lavale jõuab "Help" 9. mail, lavastajaiks Margo Teder ja Aare Toikka

Armastusest kahel ajajärgul / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2000-01-01

Mängufilm "Prantsuse leitnandi naine" ("The French Lieutenant's Woman") : stsenarist Harold Pinter John Fowles'i romaani järgi : režissöör Karel Reisz : Suurbritannia 1981. Ka : Nädal nr. 35, lk. 14

Sõjas nagu sõjas ikka / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

10-osaline sõjaseriaal "Relvavennad" ("Band of Brothers") ajalooprofessor Stephen Ambrose'i raamatu järgi : produtsendid Tom Hanks, Steven Spielberg : režissöörid Tom Hanks, David Frenkel jt. : Ameerika Ühendriigid - Suurbritannia 2001. Lühidalt ka teistest ilmasõda kajastavatest seriaalidest

Halvad, halvemad ja äravalitud / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2003-01-01

Ameerika Filmiinstituudi küsitluse järgi on maailma kõigi aegade kõige meeldejäävamaks kurjuse kehastuseks kinolinal Hannibal Lecter mängufilmides "Voonakeste vaikimine", "Hannibal" ja "Punane draakon" Anthony Hopkinsi kehastuses. Kõige sümpaatsemaks positiivseks tegelaseks valiti Atticus Finch draamas "Tappa laulurästast" Gregory Pecki kehastuses

Perekonnaportree interjööris / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2005-01-01

Lühiseriaal Mannide kirjanikedünastia saatusest 1930-1940-ndail aastail "Mannide perekond" ("Die Manns") : stsenaristid Heinrich Breloer ja Horst Königstein : režissöör Heinrich Breloer : Saksamaa 2001

Parametric analysis of AAR influent factors on thin-walled columns

Directory of Open Access Journals (Sweden)

E. L. Madureira

Full Text Available ABSTRACTThe chemical reaction involving the alkalis of the cement and some minerals of the concrete aggregates, the Alkali-Aggregate Reaction or, simply, the AAR, promotes swelling and material damages. Despite the development stage of the researches on this pathology effects, its solution modeling still lacks refinement. The numerical simulation is an important resource for the structural damages evaluation due to AAR, and their repairs. The aim of this work is the numerical simulation of concrete thin-walled columns, affected by the AAR, from the finite element approximation on an orthotropic nonlinear framework, and a thermodynamic model designed to the assessment of the AAR swelling, with highlight on the compressive stress, the reinforcement and the temperature influences on the phenomenon. The obtained results revealed that the AAR induced the concrete strength decrease and the consequent reduction in preventive safety margin to the material failure, being more precocious at higher temperatures.

Vene telesarjad sõnaga Sirbis (VII) / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2007-01-01

Kümnejaolisest telepõnevikust "Kooljate teater" ("Teatr obretshjonnõh"), stsenaristid T. Artseulova ja A. Suvorova, Mihhail Marti romaani motiividel, režissöör A. Parhomenko (MakDos/Iljuzionfilmz 2006). Võrdlus Rainer Sarneti "Libahundi needusega"

Tantsijast poksipoiss, aristokraadid ja hulluõde / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2000-01-01

IV Pimedate Ööde Filmifestivalil linastunud mängufilmidest : Suurbritannia "Billy Elliot" : režissöör Stephen Daldry, Ungari-Austria-Kanada "Päikesepaiste" ("Sunshine") : režissöör István Szab̤ ja Saksamaa "Keisrinna ja sõjamees" ("Der Krieger und die Keiserin") : režissöör Tom Tykwer

Irooniline pilguheit Iirima lähiajaloole / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2001-01-01

Mängufilm "Väike lihunik" ("The Butcher Boy") : Stsenaristid Neil Jordan ja Patrick McCabe viimase samanimelise romaani järgi : režissöör Neil Jordan : Ameerika Ühendriigid 1997. Ka : Teleleht nr. 1, lk. 4

San Sebastiani festivali varjutasid hiljutised terroriaktid / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2001-01-01

San Sebastiani rahvusvahelisel filmifestivalil sai Suure Kuldse merikarbi tšiillase Orlando Lubberti film "Takso kolmele". Parima režissööri auhinna pälvis Jean-Pierre Ameris realistliku draamaga "C'est la vie". Ka teistest auhinnatutest

Vene mõjukaim IT-guru soovitab Eesti uuendusi ida poole müüa / Henrik Roonemaa

Index Scriptorium Estoniae

Roonemaa, Henrik

2005-01-01

Eestit külastanud Venemaa mõjukamaid IT-gurusid Alexander Galitsky soovitab Eestis välja töötatud ja toimivaid innovaatilisi lahendusi pakkuda Venemaa turule. Alexander Galitsky nõustab Allan Martinsoni investeerimisfirmat Martinson Trigon Venture Partners. Vt. samas: E-riigi Akadeemia aitab firmade saavutused itta

Alkali-aggregate reactivity (AAR) facts book.

Science.gov (United States)

2013-03-01

This document provides detailed information on alkali-aggregate reactivity (AAR). It primarily discusses alkali-silica reaction (ASR), covering the chemistry, symptoms, test methods, prevention, specifications, diagnosis and prognosis, and mitigation...

IMF soovitab uue töölepinguseaduse kiiresti vastu võtta / Peep Lillemägi

Index Scriptorium Estoniae

Lillemägi, Peep, 1967-

2008-01-01

Ilmunud ka: Tallinnskii Vestnik juuli 2008, lk. 3. Eestis viibinud IMF-i delegatsiooni hinnangul sõltub Eesti majanduskasvu taastumine suurel määral majanduse konkurentsivõimest, delegatsioon toetab kavatsust leida edasisi võimalusi kokkuhoiuks ning soovitab töölepinguseaduse eelnõu kiiresti vastu võtta ja ellu viia. Rahandusminister Ivari Padari arvamus IMF-i hinnangute kohta

Animation Augmented Reality Book Model (AAR Book Model) to Enhance Teamwork

Science.gov (United States)

Chujitarom, Wannaporn; Piriyasurawong, Pallop

2017-01-01

This study aims to synthesize an Animation Augmented Reality Book Model (AAR Book Model) to enhance teamwork and to assess the AAR Book Model to enhance teamwork. Samples are five specialists that consist of one animation specialist, two communication and information technology specialists, and two teaching model design specialists, selected by…

Masendav pilguheit Ida-Saksamaa lähiajaloole / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

10. PÖFFi filme: Sakslase Florian Henkel von Donnersmarcki debüütlavastus, äsja parimaks Euroopa filmiks tunnistatud "Teiste elu" ("Das Leben der Anderen"), mehhiklase Guillermo Del Toro "Paani labürint" ("El laberinto del fauno", Mehhiko - Hispaania 2006), itaallase Nanni Moretti "Kaiman" ("The Caiman")

Luupaljas hüljesnaine ja mineviku vangid / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2010-01-01

PÖFFi filmidest: Neil Jordani "Undiin" (Iirimaa - USA, 2009), Debra Graniku "Luupaljas" (USA, 2010), Urszula Antoniaki "Ei midagi isiklikku" (Iirimaa - Holland, 2009) ja Juan Jose Campanella "Saladus nende silmades" (Hispaania - Argentiina, 2009)

Petrographic atlas characterisation of aggregates regarding potential reactivity to alkalis : RILEM TC 219-ACS recommended guidance AAR-1.2, for use with the RILEM AAR-1.1 petrographic examination method

CERN Document Server

Ribeiro, Maria; Broekmans, Maarten; Sims, Ian

2016-01-01

This RILEM AAR 1.2 Atlas is complementary to the petrographic method described in RILEM AAR 1.1. It is designed and intended to assist in the identification of alkali-reactive rock types in concrete aggregate by thin-section petrography. Additional issues include: • optical thin-section petrography conforming to RILEM AAR 1.1 is considered the prime assessment method for aggregate materials, being effective regarding cost and time. Unequivocal identification of minerals in very-fine grained rock types may however require use of supplementary methods. • the atlas adheres to internationally adopted schemes for rock classification and nomenclature, as recommended in AAR 1.1. Thus, rock types are classified as igneous, sedimentary or metamorphic based upon mineral content, microstructure and texture/fabric. • in addition, the atlas identifies known alkali-reactive silica types in each rock type presented. It also identifies consistent coincidence between certain lithologies and silica types; however, it ref...

Guide to diagnosis and appraisal of AAR damage to concrete in structures

CERN Document Server

Rooij, Mario; Wood, Jonathan

2013-01-01

This book describes procedures and methodologies used predominantly to obtain a diagnosis of damaged concrete possibly caused by Alkali-Aggregate Reaction (AAR). It has two primary objectives, namely firstly to identify the presence of AAR reaction, and whether or not the reaction is the primary or contributory cause of damage in the concrete; and secondly, to establish its intensity (severity) in various members of a structure. It includes aspects such as field inspection of the structure, sampling, petrographic examination of core samples, and supplementary tests and analyses on cores, such as mechanical tests and chemical analysis. Evaluation of test data for prognosis, consequences and appraisal will be more fully set out in AAR-6.2.

The Automated Aircraft Rework System (AARS): A system integration approach

Science.gov (United States)

Benoit, Michael J.

1994-01-01

The Mercer Engineering Research Center (MERC), under contract to the United States Air Force (USAF) since 1989, has been actively involved in providing the Warner Robins Air Logistics Center (WR-ALC) with a robotic workcell designed to perform rework automated defastening and hole location/transfer operations on F-15 wings. This paper describes the activities required to develop and implement this workcell, known as the Automated Aircraft Rework System (AARS). AARS is scheduled to be completely installed and in operation at WR-ALC by September 1994.

"Aarøes Strejfkorps - en dansk specialenhed i 1864"

DEFF Research Database (Denmark)

Papousek, Simon

2014-01-01

Boganmeldelse af genudgivelse af to artikler tidligere bragt i Militært Tidsskrift i slutningen af 1800-tallet, omhandlende oprettelsen, operationerne og historien om den danske specialenhed "Aarøes Strejfkorps" under Anden Slesvgiske Krig...

Inimelu võlu ja vaev, rassipuhtus ja koolera / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2007-01-01

PÖFFi filmidest: "Uus inimene" ("Den nya människan", rezh. Klaus Härö, Soome 2007), "Teie, kes te elate" ("Du levande", rezh. Roy Andersson, Rootsi 2007), "Armastus koolera ajal" ("Love in the Time of Cholera", Gabriel Garcia Marqueze romaani ekraniseering, rezh. Mike Newell, USA 2007)

Perfektse käsitöö poeetiline realism / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

1999-01-01

Rootsi filmiklassik Jan Troell (1931) ja tema filmid ning mängufilmid "Läbisegi" ("Topsy-Turvy") : režissöör Mike Leigh, "Rotipüüdja" ("Ratcatcher") : režissöör Lynne Ramsay ja "Püssirohutünn" ("Pure baruta") : režissöör Goran Paskaljevic Tallinnas III Pimedate Ööde Filmifestivalil

Kirjanik Truman Capote ja tema teosed valgel linal / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2006-01-01

Ameerika kirjanik Truman Capote (1924-1984) oli stsenarist viiele filmile. Tema kaks romaani on aluseks filmidele "Külmavereliselt" (RIchard Brooks, 1967) ja "Hommikueine Tiffany juures" (Blake Edwards, 1961). Edukas on mängufilm kirjanikust "Capote" : režissöör Bennett Miller : kirjanik Truman Capote' rollis Philip Seymour Hoffman : Ameerika Ühendriigid - Kanada 2005

DVD-peegel : Mondo-šokkerite pioneer Jacopetti 90 / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2009-01-01

Itaalia dokumentalistide Gualtiero Jacopetti ja Franco Prosperi šokidokumentaalidest "Mondo cane" ja "Mondo Cane 2" (1962-1963) ning "Africa Blood and Guts or Farewell Africa" ("Africa addio"/"Hüvasti, aafrika", 1966)

Sherlock Holmesi salapärane päritolu / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2004-01-01

Sir Arthur Conan Doyle'i detektiivilugudest BBC poolt aastail 2000-2001 toodetud 6-osalisest telesarjast "Mõrvatoad" ilmus Eestis kaht filmi sisaldav DVD "Sherlock Holmesi salapärane päritolu" ja "Sherlock Holmes : Patsiendi silmad"

Vittorio De Sica viis meistritööd / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2008-01-01

DVD-st "Vittorio De Sica Masterpiece Collection", kus on peal itaalia filmirežissööri Vittorio De Sica viis teost: "Jalgratavargad" ("Ladri di biciclette", 1948), "Ime Milanos" ("Miraclo a milano", 1951), "Umberto D." (1952), "Eile täna, homme" ("Ieri, oggi, domani", 1963), "Ajatu filmikunst" ("Cinema senza tempo: Cosi e la vita", 2001)

Chemoinformatics Profiling of the Chromone Nucleus as a MAO-B/A2AAR Dual Binding Scaffold.

Science.gov (United States)

Cruz-Monteagudo, Maykel; Borges, Fernanda; Cordeiro, M Natalia D S; Helguera, Aliuska Morales; Tejera, Eduardo; Paz-Y-Mino, Cesar; Sanchez-Rodriguez, Aminael; Perera-Sardina, Yunier; Perez-Castillo, Yunierkis

2017-11-14

In the context of the current drug discovery efforts to find disease modifying therapies for Parkinson's disease (PD) the current single target strategy has proved inefficient. Consequently, the search for multi-potent agents is attracting more and more attention due to the multiple pathogenetic factors implicated in PD. Multiple evidences points to the dual inhibition of the monoamine oxidase B (MAO-B), as well as adenosine A2A receptor (A2AAR) blockade, as a promising approach to prevent the neurodegeneration involved in PD. Currently, only two chemical scaffolds has been proposed as potential dual MAO-B inhibitors/A2AAR antagonists (caffeine derivatives and benzothiazinones). In this study, we conduct a series of chemoinformatics analysis in order to evaluate and advance the potential of the chromone nucleus as a MAO-B/A2AAR dual binding scaffold. The information provided by SAR data mining analysis based on network similarity graphs and molecular docking studies support the suitability of the chromone nucleus as a potential MAOB/ A2AAR dual binding scaffold. Additionally, a virtual screening tool based on a group fusion similarity search approach was developed for the prioritization of potential MAO-B/A2AAR dual binder candidates. Among several data fusion schemes evaluated, the MEAN-SIM and MIN-RANK GFSS approaches demonstrated to be efficient virtual screening tools. Then, a combinatorial library potentially enriched with MAO-B/A2AAR dual binding chromone derivatives was assembled and sorted by using the MIN-RANK and then the MEAN-SIM GFSS VS approaches. The information and tools provided in this work represent valuable decision making elements in the search of novel chromone derivatives with a favorable dual binding profile as MAOB inhibitors and A2AAR antagonists with the potential to act as a disease-modifying therapeutic for Parkinson's disease. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Analysis of PROTEUS phase II experiments performed using the AARE modular system and JEF-based libraries

International Nuclear Information System (INIS)

Pelloni, S.; Stepanek, J.; Vontobel, P.

1989-01-01

The capability of the advanced analysis of reactor engineering (AARE) modular code system and JEF-1-based nuclear data libraries to analyze light water high converter reactor (LWHCR) lattices is investigated by calculating the wet and dry cells of the PROTEUS-LWHCR phase II experiment. The results are compared to those obtained using several cell codes. Main features of the AARE code system, such as the self-shielding of resonance cross sections in the whole energy range, the generation of adequate fission source spectra, and the efficiency of the elastic removal correction,are investigated. In particular, it is shown that AARE results for the k ∞ void coefficient agree very well with the experiment, whereas other codes give larger deviations

Teletorn muutub magnetiks / Oliver Õunmaa ; kommenteerinud Aare Siimon, Raili Paling

Index Scriptorium Estoniae

Õunmaa, Oliver

2010-01-01

Aprillis algab aasta aega kestev Tallinna teletorni remont, mille käigus tehtavate muudatuste kohta jagavad selgitusi torni haldava ettevõtte Levira finantsdirektor Aare Siimon ja Arhitektuuribüroo Koko arhitekt Raili Paling

David Cronenberg ja William S. Burroughs kutsuvad teid lantshile / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

1999-01-01

Mängufilm "Alasti eine" ("Naked Lunch") William S. Burroughs' teose järgi : režissöör ja stsenarist David Cronenberg : Suurbritannia - Kanada 1991. Lähemalt režissööri kohta. Ka Nädal nr. 35, lk. 29

Aare Tool. Piiratud transponeeritavusega heliread ja vorm Eduard Oja muusikas / Mart Jaanson

Index Scriptorium Estoniae

Jaanson, Mart, 1966-

2017-01-01

Arvustus: Aare Tool. Piiratud transponeeritavusega heliread ja vorm Eduard Oja muusikas. Doktoritöö, Eesti Muusika- ja Teatriakadeemia Väitekirjad 7, Tallinn: Eesti Muusika- ja Teatriakadeemia, 2016, 125 lk.

Genome analysis of Excretory/Secretory proteins in Taenia solium reveals their Abundance of Antigenic Regions (AAR).

Science.gov (United States)

Gomez, Sandra; Adalid-Peralta, Laura; Palafox-Fonseca, Hector; Cantu-Robles, Vito Adrian; Soberón, Xavier; Sciutto, Edda; Fragoso, Gladis; Bobes, Raúl J; Laclette, Juan P; Yauner, Luis del Pozo; Ochoa-Leyva, Adrián

2015-05-19

Excretory/Secretory (ES) proteins play an important role in the host-parasite interactions. Experimental identification of ES proteins is time-consuming and expensive. Alternative bioinformatics approaches are cost-effective and can be used to prioritize the experimental analysis of therapeutic targets for parasitic diseases. Here we predicted and functionally annotated the ES proteins in T. solium genome using an integration of bioinformatics tools. Additionally, we developed a novel measurement to evaluate the potential antigenicity of T. solium secretome using sequence length and number of antigenic regions of ES proteins. This measurement was formalized as the Abundance of Antigenic Regions (AAR) value. AAR value for secretome showed a similar value to that obtained for a set of experimentally determined antigenic proteins and was different to the calculated value for the non-ES proteins of T. solium genome. Furthermore, we calculated the AAR values for known helminth secretomes and they were similar to that obtained for T. solium. The results reveal the utility of AAR value as a novel genomic measurement to evaluate the potential antigenicity of secretomes. This comprehensive analysis of T. solium secretome provides functional information for future experimental studies, including the identification of novel ES proteins of therapeutic, diagnosis and immunological interest.

Aare Sosaar nõuab sisse ERA Panga halbu laene / Tiit Elner

Index Scriptorium Estoniae

Elner, Tiit

2000-01-01

Ekspankur Aare Sosaare juhitav teadmata omanikega ERA Liising ostis pankrotis ERA Pangalt probleemseid laene, suurem nõuete ostja oli ka Krediidipank. Kokku on müüdud laenude lepingujärgne väärtus kuni 100 mln. kr.

Estonia : a European tax paradise? / Aare Kurist, Madis Müller

Index Scriptorium Estoniae

Kurist, Aare, 1974-

2003-01-01

PricewaterhouseCoopersi maksuosakonna juhataja Aare Kurist ja peaministri majandusnõunik Madis Müller analüüsivad 2000. aastal toimunud maksureformi eesmärke ja nende täitmist, prognoosivad EL-i liitumisläbirääkimiste võimalikku mõju Eesti maksupoliitikale ja võimalikku vajadust tulevikus Eesti maksukorralduse muutmiseks

A subaquatic moraine complex in overdeepened Lake Thun (Switzerland) unravelling the deglaciation history of the Aare Glacier

Science.gov (United States)

Fabbri, S. C.; Buechi, M. W.; Horstmeyer, H.; Hilbe, M.; Hübscher, C.; Schmelzbach, C.; Weiss, B.; Anselmetti, F. S.

2018-05-01

To investigate the history of the Aare Glacier and its overdeepened valley, a high-resolution multibeam bathymetric dataset and a 2D multi-channel reflection seismic dataset were acquired on perialpine Lake Thun (Switzerland). The overdeepened basin was formed by a combination of tectonically predefined weak zones and glacial erosion during several glacial cycles. In the deepest region of the basin, top of bedrock lies at ∼200 m below sea level, implying more than 750 m of overdeepening with respect to the current fluvial base level (i.e. lake level). Seismic stratigraphic analysis reveals the evolution of the basin and indicates a subaquatic moraine complex marked by high-amplitude reflections below the outermost edge of a morphologically distinct platform in the southeastern part of the lake. This stack of seven subaquatic terminal moraine crests was created by a fluctuating, "quasi-stagnant" grounded Aare Glacier during its overall recessional phase. Single packages of overridden moraine crests are seismically distuinguishable, which show a transition downstream into prograding clinoforms with foresets at the ice-distal slope. The succession of subaquatic glacial sequences (foresets and adjacent bottomsets) represent one fifth of the entire sedimentary thickness. Exact time constraints concerning the deglacial history of the Aare Glacier are very sparse. However, existing 10Be exposure ages from the accumulation area of the Aare Glacier and radiocarbon ages from a Late-Glacial lake close to the outlet of Lake Thun indicate that the formation of the subaquatic moraine complex and the associated sedimentary infill must have occurred in less than 1000 years, implying high sedimentation rates and rapid disintegration of the glacier. These new data improve our comprehension of the landforms associated with the ice-contact zone in water, the facies architecture of the sub- to proglacial units, the related depositional processes, and thus the retreat mechanisms of

AAR at Hydro-Quebec : a review of field cases and intervention strategies

Energy Technology Data Exchange (ETDEWEB)

Durand, B. [Hydro-Quebec, Varennes, PQ (Canada). IREQ

2006-07-01

Hydro-Quebec owns and operates more than 560 dams, including 200 dams that are classified as large dams. By 2010, approximately 150 of the concrete dams will be at least 50 years old, and nearly 100 of the dams will be 70 years old. The current condition of these structures reflects the influence of several factors that have promoted aging, such as initial shrinkage causing latent microcracking; expansion and contraction related to temperature cycles; larger infiltration entailing increased uplift; leaching and deposition of calcium salts that clog joints and drains; hydric swelling; freezing and thawing cycles; erosion; sulfation; and, alkali-aggregate reactions (AAR). This paper focused on the swelling due to AAR, since more than 20 dams have been affected by this condition. Hydro-Quebec's approach to prevent AAR was described. In response to Canadian Standards Association (CSA) concrete expansion tests, Hydro-Quebec no longer allows admixtures for its concrete structures. Rather, non-reactive aggregates are used in the concrete. This paper also discussed the evaluation of residual expansion time caused by the alkali-silica reaction (ASR), which has affected the dam at La Tuque in the Mauricie Region. Results of laboratory expansion tests have been compared with the average expansion rate measured at the La Tuque dam. It was estimated that the concrete should continue to swell for at least 20 years at the same rate as measured since 1979. After that, expansion may possibly slow down due to self-confinement in the concrete. However, if confinement increases in 2 directions, it is probable that the expansion accelerates in the third direction. 26 refs., 3 tabs., 8 figs.

Research on Standard and Automatic Judgment of Press-fit Curve of Locomotive Wheel-set Based on AAR Standard

Science.gov (United States)

Lu, Jun; Xiao, Jun; Gao, Dong Jun; Zong, Shu Yu; Li, Zhu

2018-03-01

In the production of the Association of American Railroads (AAR) locomotive wheel-set, the press-fit curve is the most important basis for the reliability of wheel-set assembly. In the past, Most of production enterprises mainly use artificial detection methods to determine the quality of assembly. There are cases of miscarriage of justice appear. For this reason, the research on the standard is carried out. And the automatic judgment of press-fit curve is analysed and designed, so as to provide guidance for the locomotive wheel-set production based on AAR standard.

The small hydropower plant in the old river Aare in Niedergoesgen, Switzerland; Kleinwasserkraftwerk Ballyschwelle, alte Aare, Niedergoesgen. Vorprojekt

Energy Technology Data Exchange (ETDEWEB)

Eichenberger, P.

2007-07-15

This preliminary project for the Swiss Federal Office of Energy (SFOE) presents a project which proposes the construction of a new small hydro plant in Niedergoesgen/Gretzenbach, Switzerland, that is to make use of the waters of the old river Aare. The project proposes the construction of a new, 350 kW plant at the site of an existing sill across the old river that originally formed part of a water-power installation given up in 1917. The existing parts of the old installation are described and the legal situation concerning water rights and land ownership are examined. Three variants for a new installation are described. Technical figures and energy-production estimates for a new installation are discussed. Ecological aspects are examined, as are the recreational aspects of the river at this location. Cost estimates and economic viability are discussed.

Piimatööstused kukkusid kahjumisse / Aare Annus ; interv. Silja Lättemäe

Index Scriptorium Estoniae

Annus, Aare

2005-01-01

Tallinna Piimatööstuse AS-i nõukogu esimees Aare Annus Eesti piimatööstuste raskest olukorrast seoses toorpiima kõrge kokkuostuhinnaga. Vt. ka: Kas saite piimahinnast kõva kasumit? Küsimusele vastavad Järvamaa talunik Arvo Kuutok ja Põlva Agro OÜ nõukogu esimees Jaak Hinrikus

Adult Attachment Ratings (AAR): an item response theory analysis.

Science.gov (United States)

Pilkonis, Paul A; Kim, Yookyung; Yu, Lan; Morse, Jennifer Q

2014-01-01

The Adult Attachment Ratings (AAR) include 3 scales for anxious, ambivalent attachment (excessive dependency, interpersonal ambivalence, and compulsive care-giving), 3 for avoidant attachment (rigid self-control, defensive separation, and emotional detachment), and 1 for secure attachment. The scales include items (ranging from 6-16 in their original form) scored by raters using a 3-point format (0 = absent, 1 = present, and 2 = strongly present) and summed to produce a total score. Item response theory (IRT) analyses were conducted with data from 414 participants recruited from psychiatric outpatient, medical, and community settings to identify the most informative items from each scale. The IRT results allowed us to shorten the scales to 5-item versions that are more precise and easier to rate because of their brevity. In general, the effective range of measurement for the scales was 0 to +2 SDs for each of the attachment constructs; that is, from average to high levels of attachment problems. Evidence for convergent and discriminant validity of the scales was investigated by comparing them with the Experiences of Close Relationships-Revised (ECR-R) scale and the Kobak Attachment Q-sort. The best consensus among self-reports on the ECR-R, informant ratings on the ECR-R, and expert judgments on the Q-sort and the AAR emerged for anxious, ambivalent attachment. Given the good psychometric characteristics of the scale for secure attachment, however, this measure alone might provide a simple alternative to more elaborate procedures for some measurement purposes. Conversion tables are provided for the 7 scales to facilitate transformation from raw scores to IRT-calibrated (theta) scores.

Sissejuhatus suure kirjaniku loomingusse : Edgar Allan Poe' väändunud maailm / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2001-01-01

Prantsusmaa-Itaalia 1968.a. ühisfilm "Erakordsed lood" ("Histoires extraordinaires"), mis koosneb Edgar Allan Poe kolme novelli ekraniseeringutest : "Metzengerstein" (režissöör Roger Vadim), "William Wilson" (režissöör Louis Malle) ja "Toby Dammit" (režissöör Federico Fellini). Ka : Nädal nr. 25, lk. 14

Filmikurioosumid : Kõige, kõige, kõige filmid : Zorrod läbi aegade / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

2002-01-01

1919. aastal ilmunud Johnston McCulley jutustus "Capistrano needus" pani aluse lugematutele vaeste eest maskis ja pimeduse varjus kättemaksva Zorro lugudele trükisõnas ja kinolinal. Samast tüvest on pärit ka Batmani (looja Bob Kane) ja Supermani lood

The timing of the maximum extent of the Rhone Glacier at Wangen a.d. Aare

Energy Technology Data Exchange (ETDEWEB)

Ivy-Ochs, S.; Schluechter, C. [Bern Univ. (Switzerland); Kubik, P.W. [Paul Scherrer Inst. (PSI), Villigen (Switzerland); Beer, J. [EAWAG, Duebendorf (Switzerland)

1997-09-01

Erratic blocks found in the region of Wangen a.d. Aare delineate the maximum position of the Solothurn lobe of the Rhone Glacier. {sup 10}Be and {sup 26}Al exposure ages of three of these blocks show that the glacier withdraw from its maximum position at or slightly before 20,000{+-}1800 years ago. (author) 1 fig., 5 refs.

Genotype/phenotype correlations in AARS-related neuropathy in a cohort of patients from the United Kingdom and Ireland.

Science.gov (United States)

Bansagi, Boglarka; Antoniadi, Thalia; Burton-Jones, Sarah; Murphy, Sinead M; McHugh, John; Alexander, Michael; Wells, Richard; Davies, Joanna; Hilton-Jones, David; Lochmüller, Hanns; Chinnery, Patrick; Horvath, Rita

2015-08-01

Charcot-Marie-Tooth disease (CMT) is the most common inherited neuropathy with heterogeneous clinical presentation and genetic background. The axonal form (CMT2) is characterised by decreased action potentials indicating primary axonal damage. The underlying pathology involves axonal degeneration which is supposed to be related to axonal protein dysfunction caused by various gene mutations. The overlapping clinical manifestation of CMT2 with distal hereditary motor neuropathy (dHMN) and intermediate CMT causes further diagnostic difficulties. Aminoacyl-tRNA synthetases have been implicated in the pathomechanism of CMT2. They have an essential role in protein translation by attaching amino acids to their cognate tRNAs. To date six families have been reported worldwide with dominant missense alanyl-tRNA synthetase (AARS) mutations leading to clinically heterogeneous axonal neuropathies. The pathomechanism of some variants could be explained by impaired amino acylation activity while other variants implicating an editing defect need to be further investigated. Here, we report a cohort of six additional families originating from the United Kingdom and Ireland with dominant AARS-related neuropathies. The phenotypic manifestation was distal lower limb predominant sensorimotor neuropathy but upper limb impairment with split hand deformity occasionally associated. Nerve conduction studies revealed significant demyelination accompanying the axonal lesion in motor and sensory nerves. Five families have the c.986G>A, p.(Arg329His) variant, further supporting that this is a recurrent loss of function variant. The sixth family, of Irish origin, had a novel missense variant, c.2063A>G, p.(Glu688Gly). We discuss our findings and the associated phenotypic heterogeneity in these families, which expands the clinical spectrum of AARS-related neuropathies.

Quantification and dating of floodplain sedimentation in a medium-sized catchment of the German uplands: a case study from the Aar Valley in the southern Rhenish Massif, Germany

Directory of Open Access Journals (Sweden)

Stolz, Christian

2013-09-01

Full Text Available The distribution, thickness and composition of the floodplain sediments in the valleys of the Aar and its tributaries (Taunus Mountains were investigated by way of extensive fieldwork at 25 locations. In the entire catchment area, 48.8 million tons of loamy f loodplain fines could be assessed. Most of these were deposited since late medieval times due to extensive historical land use and forest clearing, especially in the mining region along the middle course of the Aar. In its lower course, the enhanced sedimentation of loamy f loodplain sediments started during the Bronze Age.

Internal structure of the Aar Massif: What can we learn in terms of exploration for deep geothermal energy?

Science.gov (United States)

Herwegh, Marco; Baumberger, Roland; Wehrens, Philip; Schubert, Raphael; Berger, Alfons; Maeder, Urs; Spillmann, Thomas

2014-05-01

The successful use of deep geothermal energy requires 3D flow paths, which allow an efficient heat exchange between the surrounding host rocks and the circulating fluids. Recent attempts to exploit this energy resource clearly demonstrate that the new technology is facing sever problems. Some major problems are related to the prediction of permeability, the 3D structure of the flow paths and the mechanical responses during elevated fluid pressures at depths of several kilometers. Although seemingly new in a technical perspective, nature is facing and solving similar problems since the beginning of the Alpine orogeny. Based on detailed studies in the Hasli Valley (Aar Massif) we can demonstrate that deformation and fluid flow are strongly localized along mechanical anisotropies (e.g. lithological variations, brittle and ductile faults). Some of them already evolved during Variscan and post-Variscan times. Interestingly, these inherited structures are reactivated over and over again during the Alpine orogeny. Their reactivation occurred at depths of ~13-15 km with elevated temperatures (400-475°C) and involved both ductile and brittle deformation processes. Brittle deformation in form of hydrofracking was always present due to the circulating fluids. It is this process, which was and still is responsible for seismic activity. With progressive uplift and exhumation of the Aar Massif, ductile deformation structures became replaced by brittle cataclasites and fault gouges during fault activity at shallower crustal levels. Existing hydrotest data from the Grimsel Test Site (Nagra's underground research laboratory) indicate that these brittle successors of the ductile shear zones are domains of enhanced recent fluid percolation. Note that although being exposed today, the continuation of these fault structures are still active at depth in both brittle and ductile deformation modes, a fact that can be inferred from recent uplift rates and the active seismicity. On the

Automation of hydro power on the upper Rhine and modernization of a power station at the confluence of the Rhine and Aare rivers; Automatisierung der Wasserwirtschaft am Hochrhein und Modernisierung eines Kraftwerkes am Zusammenfluss von Aare und Rhein

Energy Technology Data Exchange (ETDEWEB)

Beltzig, C.; Schlageter, G.

1996-12-31

For the first barrage weir after the confluence of the Rhine and Aare rivers, a maximum storage level is determined and set that constitutes an operating optimum and takes the different inflow and outfall volumes as well as existing retention capacities into account. Moreover, the process control system ensures automatic operation of the three engine units of the power station including process control of the barrage weir and the external systems belonging to the Albbruck-Doggern hydroelectric power station on the Rhine (RADAG). (orig./RHM)

The small hydropower plant in the old river Aare in Niedergoesgen, Switzerland

International Nuclear Information System (INIS)

Eichenberger, P.

2007-07-01

This preliminary project for the Swiss Federal Office of Energy (SFOE) presents a project which proposes the construction of a new small hydro plant in Niedergoesgen/Gretzenbach, Switzerland, that is to make use of the waters of the old river Aare. The project proposes the construction of a new, 350 kW plant at the site of an existing sill across the old river that originally formed part of a water-power installation given up in 1917. The existing parts of the old installation are described and the legal situation concerning water rights and land ownership are examined. Three variants for a new installation are described. Technical figures and energy-production estimates for a new installation are discussed. Ecological aspects are examined, as are the recreational aspects of the river at this location. Cost estimates and economic viability are discussed.

Using the accelerated Brazilian concrete prism test (ABCPT to evaluate alkali aggregate reaction (AAR

Directory of Open Access Journals (Sweden)

L. Sanchez

Full Text Available There are many test methods used in the laboratory to detect potential alkali-aggregate reactions (AAR. However, up to now, there is no consensus if they are reliable and efficient. This work presents the development of a new and accelerated concrete prism test called ABCPT (accelerate Brazilian concrete prism test as an attempt to create a reliable and fast test that can analyze and classify the potential reactivity of aggregates in the laboratory. For this research, six aggregates from different lithotypes were used. The methods CPT, ACPT and ABCPT were carried out with all the aggregates and a comparative analysis among all tests was performed. ABCPT seems to have a great potential to analyze and classify aggregates in the laboratory, although it needs further testing with other lithotypes to be confirmed as feasible.

Teatrikunstnik Iir Hermeliin - maagiline realist / Iir Hermeliin ; intervjueerinud Tiina Kolk, kommenteerinud Dmitri Demjanov, Evelin Kattai

Index Scriptorium Estoniae

Iir Hermeliin, pseud., 1973-

2010-01-01

Iir Hermeliini (Hille Ermel) teatritööst, talle olulistest paikadest Eestimaal, elust Kalamajas, välisreisidest, huvist kokanduse vastu, kunstiõpingutest, inspiratsiooniallikatest. Loetletud saadud autasud, valik lavastusi

Structural modeling of tissue-specific mitochondrial alanyl-tRNA synthetase (AARS2 defects predicts differential effects on aminoacylation

Directory of Open Access Journals (Sweden)

Liliya eEuro

2015-02-01

Full Text Available The accuracy of mitochondrial protein synthesis is dependent on the coordinated action of nuclear-encoded mitochondrial aminoacyl-tRNA synthetases (mtARSs and the mitochondrial DNA-encoded tRNAs. The recent advances in whole-exome sequencing have revealed the importance of the mtARS proteins for mitochondrial pathophysiology since nearly every nuclear gene for mtARS (out of 19 is now recognized as a disease gene for mitochondrial disease. Typically, defects in each mtARS have been identified in one tissue-specific disease, most commonly affecting the brain, or in one syndrome. However, mutations in the AARS2 gene for mitochondrial alanyl-tRNA synthetase (mtAlaRS have been reported both in patients with infantile-onset cardiomyopathy and in patients with childhood to adulthood-onset leukoencephalopathy. We present here an investigation of the effects of the described mutations on the structure of the synthetase, in an effort to understand the tissue-specific outcomes of the different mutations.The mtAlaRS differs from the other mtARSs because in addition to the aminoacylation domain, it has a conserved editing domain for deacylating tRNAs that have been mischarged with incorrect amino acids. We show that the cardiomyopathy phenotype results from a single allele, causing an amino acid change p.R592W in the editing domain of AARS2, whereas the leukodystrophy mutations are located in other domains of the synthetase. Nevertheless, our structural analysis predicts that all mutations reduce the aminoacylation activity of the synthetase, because all mtAlaRS domains contribute to tRNA binding for aminoacylation. According to our model, the cardiomyopathy mutations severely compromise aminoacylation whereas partial activity is retained by the mutation combinations found in the leukodystrophy patients. These predictions provide a hypothesis for the molecular basis of the distinct tissue-specific phenotypic outcomes.

Veider nelik jätkab!

Index Scriptorium Estoniae

2008-01-01

Arvutiga animeeritud USA koguperefilmist "Madagaskar 2" (lavastanud Tim McGrath ja Eric Darnell, eesti keeles loevad teksti Karol Kuntsel, Andero Ermel, Evelin Pang, Argo Aadli, Mait Malmsten, Raivo E. Tamm, Andrus Vaarik, Anne Reemann jt)

Linn otsib logo ja tunnusmuusikat / Erki Varma

Index Scriptorium Estoniae

Varma, Erki

2003-01-01

Konkursile Tallinna linna logo ja tunnusmuusika saamiseks laekunud töid ei peetud õnnestunuiks. Žüriis Aavo Ermel, Jüri Kass ja Riho Rõõmus. Kommentaar Allan Alakülalt. Reklaamibüroo Zoom 6 kavandit

Diagnostic Accuracy of APRI, AAR, FIB-4, FI, and King Scores for Diagnosis of Esophageal Varices in Liver Cirrhosis: A Retrospective Study.

Science.gov (United States)

Deng, Han; Qi, Xingshun; Peng, Ying; Li, Jing; Li, Hongyu; Zhang, Yongguo; Liu, Xu; Sun, Xiaolin; Guo, Xiaozhong

2015-12-20

BACKGROUND Aspartate aminotransferase-to-platelet ratio index (APRI), aspartate aminotransferase-to-alanine aminotransferase ratio (AAR), FIB-4, fibrosis index (FI), and King scores might be alternatives to the use of upper gastrointestinal endoscopy for the diagnosis of esophageal varices (EVs) in liver cirrhosis. This study aimed to evaluate their diagnostic accuracy in predicting the presence and severity of EVs in liver cirrhosis. MATERIAL AND METHODS All patients who were consecutively admitted to our hospital and underwent upper gastrointestinal endoscopy between January 2012 and June 2014 were eligible for this retrospective study. Areas under curve (AUCs) were calculated. Subgroup analyses were performed according to the history of upper gastrointestinal bleeding (UGIB) and splenectomy. RESULTS A total of 650 patients with liver cirrhosis were included, and 81.4% of them had moderate-severe EVs. In the overall analysis, the AUCs of these non-invasive scores for predicting moderate-severe EVs and presence of any EVs were 0.506-0.6 and 0.539-0.612, respectively. In the subgroup analysis of patients without UGIB, their AUCs for predicting moderate-severe varices and presence of any EVs were 0.601-0.664 and 0.596-0.662, respectively. In the subgroup analysis of patients without UGIB or splenectomy, their AUCs for predicting moderate-severe varices and presence of any EVs were 0.627-0.69 and 0.607-0.692, respectively. CONCLUSIONS APRI, AAR, FIB-4, FI, and King scores had modest diagnostic accuracy of EVs in liver cirrhosis. They might not be able to replace the utility of upper gastrointestinal endoscopy for the diagnosis of EVs in liver cirrhosis.

"Tallinna moodul" pakub linnale ühtset vormi / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2004-01-01

Rahvusvahelise ideekonkursi võitis "Fold", autorid Clayton Welham ja Martin Yong Londonist. II koht tööle "Drunken Style", autorid Samson Adjei, Harry Dobbs Ja Greg Epps Londonist. III koht itaalia disaineritele, ergutuspreemiad Argentiinasse ja New Yorki. Kommenteerinud linnadisainer Aavo Ermel

Loomad räägivad sel korral eesti keeles / Jaanus Noormets

Index Scriptorium Estoniae

Noormets, Jaanus

2008-01-01

Arvutiga animeeritud USA koguperefilmist "Madagaskar 2" (Madagascar: Escape 2 Africa), mis jõuab Eesti kinodesse erinevalt filmisarja esimesest osast eesti keelde dubleerituna (loomtegelastele on oma hääle laenanud Karol Kuntsel, Andero Ermel, Evelin Pang, Mait Malmsten, Raivo E. Tamm, Andrus Vaarik jt)

How Primary Teacher Teams Understand the Team Protocol in Ohio

Science.gov (United States)

Willoughby, Julie

2016-01-01

Teacher teams can be more effective when protocols are used in their entirety; and because of this, use of and understanding Ohio's five-step process is important (Gallimore, Ermeling, Saunders & Goldenberg, 2009, Saunders, Goldenberg & Gallimore, 2009, and Schwaenberger & Ahearn, 2013). This study explored the understanding of…

Tolko poetom hotel bõt : Rastrogannost; Dozhdlivõi den; Jaanov ogon; Setumaa I-II; Tolko poetom. Haralskije zhizneopissanija : Aire Valgus; Aare Valgus; Peeter Petrov; Vaike Metsleht; Valdur Laiapea; Hillar Aruda, ekonomist; Pärja Lumendi; Valjo Z

Index Scriptorium Estoniae

Traat, Mats, 1936-

1996-01-01

Orig.: Heldimus; Sajupäev; Jaanituli; Setumaa I-II; Ainult poeet. Harala elulood: Aire Valgus; Aare Valgus; Peeter Petrov; Vaike Metsleht; Valdur Laiapea; Hillar Aruda, ökonomist; Pärja Lumendi; Valjo Zeiger; Pavlo Moskalenko; Johannes Iva; Viljar Laanemägi; Olga Kaljusaar; Aimi Vaimets; Einard Kalm (1923-1984); Sonetid vaikimisest I; Kui

SU-E-T-644: QuAArC: A 3D VMAT QA System Based On Radiochromic Film and Monte Carlo Simulation of Log Files

Energy Technology Data Exchange (ETDEWEB)

Barbeiro, A.R.; Ureba, A.; Baeza, J.A.; Jimenez-Ortega, E.; Plaza, A. Leal [Universidad de Sevilla, Departamento de Fisiologia Medica y Biofisica, Seville (Spain); Linares, R. [Hospital Infanta Luisa, Servicio de Radiofisica, Seville (Spain); Mateos, J.C.; Velazquez, S. [Hospital Universitario Virgen del Rocio, Servicio de Radiofisica, Seville (Spain)

2015-06-15

Purpose: VMAT involves two main sources of uncertainty: one related to the dose calculation accuracy, and the other linked to the continuous delivery of a discrete calculation. The purpose of this work is to present QuAArC, an alternative VMAT QA system to control and potentially reduce these uncertainties. Methods: An automated MC simulation of log files, recorded during VMAT treatment plans delivery, was implemented in order to simulate the actual treatment parameters. The linac head models and the phase-space data of each Control Point (CP) were simulated using the EGSnrc/BEAMnrc MC code, and the corresponding dose calculation was carried out by means of BEAMDOSE, a DOSXYZnrc code modification. A cylindrical phantom was specifically designed to host films rolled up at different radial distances from the isocenter, for a 3D and continuous dosimetric verification. It also allows axial and/or coronal films and point measurements with several types of ion chambers at different locations. Specific software was developed in MATLAB in order to process and evaluate the dosimetric measurements, which incorporates the analysis of dose distributions, profiles, dose difference maps, and 2D/3D gamma index. It is also possible to obtain the experimental DVH reconstructed on the patient CT, by an optimization method to find the individual contribution corresponding to each CP on the film, taking into account the total measured dose, and the corresponding CP dose calculated by MC. Results: The QuAArC system showed high reproducibility of measurements, and consistency with the results obtained with the commercial system implemented in the verification of the evaluated treatment plans. Conclusion: A VMAT QA system based on MC simulation and high resolution dosimetry with film has been developed for treatment verification. It shows to be useful for the study of the real VMAT capabilities, and also for linac commissioning and evaluation of other verification devices.

Stekljannaja stena - simvol protivostojanija estontsev / Dagne Hanschmidt

Index Scriptorium Estoniae

Hanschmidt, Dagne

2006-01-01

Eesti Reservohvitseride Kogu algatatud vastupanumälestusmärgi ideekonkursi tulemustest. Monument püstitatakse Tallinnasse välisministeeriumi hoone ette. Võidutööst (autor avalikustamata). Kommenteerivad Aavo Ermel ja Eerik-Niiles Kross. Vaata ka lk. 1. Teise koha sai Ernst Jaaksoni eskiis metsavendadega ja kolmanda koha eskiis "Sein"

Uus tehnoloogia vajab uut juhtimist / Derek Abell

Index Scriptorium Estoniae

Abell, Derek

2001-01-01

Lausanne'is asuva International Institut for Management Development'i juhtimisprofessor soovitab tippjuhtideks edutada juristide ja turundajate kõrval ka insenere. Tähtsaimad sammud tegevjuhtkonna jaoks

Las erastajad maksavad oma korteri turuhinnas kinni! / Ester Shank

Index Scriptorium Estoniae

Šank, Ester, 1956-

2008-01-01

Tallinna linnavolikogu esimees Toomas Vitsut soovitab sundüürnikele tehtud riikliku ülekohtu heastamist ebaõiglaseks pidavatel linnavolinikel maksta linnakassase summa, mille nad omandireformiga isiklikult võitsid

Quantitative assessment of alkali-reactive aggregate mineral content through XRD using polished sections as a supplementary tool to RILEM AAR-1 (petrographic method)

International Nuclear Information System (INIS)

Castro, Nélia; Sorensen, Bjørn E.; Broekmans, Maarten A.T.M.

2012-01-01

The mineral content of 5 aggregate samples from 4 different countries, including reactive and non-reactive aggregate types, was assessed quantitatively by X-ray diffraction (XRD) using polished sections. Additionally, electron probe microanalyzer (EPMA) mapping and cathodoluminescence (CL) were used to characterize the opal-CT identified in one of the aggregate samples. Critical review of results from polished sections against traditionally powdered specimen has demonstrated that for fine-grained rocks without preferred orientation the assessment of mineral content by XRD using polished sections may represent an advantage over traditional powder specimens. Comparison of data on mineral content and silica speciation with expansion data from PARTNER project confirmed that the presence of opal-CT plays an important role in the reactivity of one of the studied aggregates. Used as a complementary tool to RILEM AAR-1, the methodology suggested in this paper has the potential to improve the strength of the petrographic method.

Eesti Post haarab õlekõrrest? / Enn Vatter

Index Scriptorium Estoniae

Vatter, Enn

2007-01-01

AS Eesti Post 2006. aasta majandusaruandest ja ettevõtte majandusraskustest. Autor soovitab abi otsida riigikontrollist, kes suunaks AS Eesti Posti õigetele majandamisrööbastele. Diagrammid: Eesti Posti palgatõus

Osta seda, mida teised ei taha / Villu Zirnask

Index Scriptorium Estoniae

Zirnask, Villu, 1966-

2005-01-01

Investeerimisfondide analüüsiga tegelev firma Morningstar soovitab investoritel kasutada investeerimisstrateegiat, mis seisneb ebapopulaarsete investeerimisfondide osakute ostmises. Lisa: Kõige ebapopulaarsemad investeerimissektorid USA-s aastatel 1994-2004 (investeerimisfondide rahavoogude alusel)

Trendid, millega maailmaturul rikastuda / Kertu Ruus

Index Scriptorium Estoniae

Ruus, Kertu, 1977-

2007-01-01

Londonis elav USA investeerimisekspert Nicholas Vardy toob välja viis trendi, millega soovitab arvestada investeerimisel. Vt. samas: Vardy: Eesti Hiinast tähtsam; Nicholas Vardy soovitatud aktsiad; Nicholas Vardy

9. sajandi piiblileheküljest luubiga loetavate kääbusraamatuteni / Silja Ratt, Aigi Viira

Index Scriptorium Estoniae

Ratt, Silja

2016-01-01

Haruldastest raamatutest neljas Eesti raamatukogus. Selgitusi jagavad keskaegsete käsikirjade uurija Kaspar Kolk, TÜ raamatukogu käsikirjade ja haruldaste raamatute osakonna juhataja Malle Ermel, Eesti Rahvusraamatukogu kogude osakonna juhataja-peavarahoidja Kaire Lass, TLÜ akadeemilise raamatukogu vanaraamatu spetsialist Kaja Tiisel, Baltika ja vanaraamatu säilitamise osakonna juhataja Aija Sakova-Merivee ja säilitamise peaspetsialist Rene Haljasmäe ning Eesti Kirjandusmuuseumi arhiivraamatukogu juhataja Merike Kiipus

Fond dlja borbõ s pjatnami na reputatsii / Jevgenia Garanzha

Index Scriptorium Estoniae

Garanža, Jevgenija, 1979-

2007-01-01

Eestimaa Looduse Fond (ELF) kutsub vabatahtlikke õppima, kuidas päästa õliseid linde. Endine Valdese linnapea Alaskalt John Devens soovitab Eestil luua ökokatastroofide likvideerimisfond, mida rahastaksid töösturid

Katseta, analüüsi, kohanda / Villu Zirnask

Index Scriptorium Estoniae

Zirnask, Villu, 1966-

2012-01-01

Suurbritannia valitsuse juurde loodud töörühm Behavioural Insights Team soovitab poliitika tõhususe parandamiseks kasutada kontrollrühmade meetodit, mida on varem rakendatud näiteks ravimite katsetamisel

Tallink jättis eilsel börsipäeval väikeaktsionärid infosulgu / Annika Matson

Index Scriptorium Estoniae

Matson, Annika, 1976-

2006-01-01

Tallink ei andnud erinevalt Viking Line'ist oma väikeaktsionäridele teada, kas osaleb Silja Line'i ostupakkumisel. Kommenteerib Raul Malmstein. Vt. samas: Lauri Matsulevitsh. Citigroup soovitab Tallinki aktsiat osta

Avafilm on "Puude kuninganna" / Urmas Tartes

Index Scriptorium Estoniae

Tartes, Urmas, 1963-

2007-01-01

Professor soovitab Haapsalu kuursaalis Matsalu loodusfilmifestivali programmi avafilmi "Puude kuninganna" ("The Qeen of Trees") : režissöörid Mark Deeble, Victoria Stone : Suurbritannia - Keenia - Jaapan - Ameerika Ühendriigid - Saksamaa. Filmitud Keenias

Korrastame kodused kogud / Vaike Hang

Index Scriptorium Estoniae

Hang, Vaike, 1932-

2004-01-01

Autor soovitab oma kodused kogud ja arhiivid süstematiseerida, tuues näiteks geograafiaprofessori Endel Varepi (1915-1988), ornitoloogiaprofessori Eerik Kumari (1912-1984) ja dr. phil. Gustav Vilbaste (1885-1967) kodused arhiivid

Rahvusvaheline mees Mart Laar = Mart Laar, international man / Ingvar Bärenklau

Index Scriptorium Estoniae

Bärenklau, Ingvar, 1967-

2006-01-01

Eesti ekspeaministri Mart Laari uutest väljakutsetest pärast Milton Friedmani nimelise auhinna saamist. Lisad: Fakte Mart Laari kohta; Teised Mart Laarist. Vt. samas: Laar soovitab suvisel Eestimaal ringi sõita

Kultuuritehase festival surmab publiku ees Autori / Anne Vetik

Index Scriptorium Estoniae

Vetik, Anne

2006-01-01

Kultuuritehase Polymer 18.-27. augustini 2006 Tallinnas toimuv kolmas festival pakub moodsaid skulptuure ja ehtekunsti. Projektijuht Heiki Hiis soovitab kunstieksperimenti "Autori surm" (kuraator moekunstnik Ester Kannelmäe). Kultuuritehase kolimisest vanasse Tallinna elektrijaama katlamajja

East Capital suunab investorid Venemaale / Gert Tiivas ; interv. Raivo Sormunen

Index Scriptorium Estoniae

Tiivas, Gert, 1973-

2007-01-01

Rootsi investeerimispanga East Capitali Balti regiooni juht Gert Tiivas soovitab investeerida Baltimaadest suurema potentsiaaliga riikide börsidele. Vt. samas: CV: Gert Tiivas; East Capitali fondid. Diagramm: East Capitali Venemaa fondis on enim raha

Brussels distributes warnings to Baltic countries

Index Scriptorium Estoniae

2005-01-01

Euroopa Komisjon soovitab tungivalt Eesti, Läti ja Malta transpordiministritel võidelda lennukitest põhjustatud müra tasemega ning tuua selle regulatsioonid Euroopalikule tasemele. Mitmeid ettekirjutusi Euroopa Liidu liikmesriikidele erinevates küsimustes

Ozero kormit no s perebojami / Jevgeni Ashihmin

Index Scriptorium Estoniae

Ashihmin, Jevgeni

2007-01-01

Kalapüügifirma OÜ Peipus direktor Vadim Ivanov hindab kriitiliselt keskkonnaministeeriumi ja põllumajandusministeeriumi otsuseid, mis reguleerivad kalapüüki Peipsi järvest ja soovitab rohkem usaldada Peipsi Kalurite Liidu arvamust

The Incidence, Classification, and Management of Acute Adverse Reactions to the Low-Osmolar Iodinated Contrast Media Isovue and Ultravist in Contrast-Enhanced Computed Tomography Scanning.

Science.gov (United States)

Zhang, Bin; Dong, Yuhao; Liang, Long; Lian, Zhouyang; Liu, Jing; Luo, Xiaoning; Chen, Wenbo; Li, Xinyu; Liang, Changhong; Zhang, Shuixing

2016-03-01

Some epidemiologic surveillance studies have recorded adverse drug reactions to radiocontrast agents. We aimed to investigate the incidence and management of acute adverse reactions (AARs) to Ultravist-370 and Isovue-370 in patients who underwent contrast-enhanced computed tomography (CT) scanning.Data from 137,473 patients were analyzed. They had undergone enhanced CT scanning with intravenous injection of Ultravist-370 or Isovue-370 during the period of January 1, 2006 to December 31, 2012 in our hospital. We investigated and classified AARs according to the American College of Radiology and the Chinese Society of Radiology (CSR) guidelines for iodinated contrast media. We analyzed risk factors for AARs and compared the AARs induced by Ultravist-370 and Isovue-370.Four hundred and twenty-eight (0.31%) patients experienced AARs, which included 330 (0.24%) patients with mild AARs, 82 (0.06%) patients with moderate AARs, and 16 (0.01%) patients with severe AARs (including 3 cases of cardiac arrest and one case of death). The incidence of AARs was higher with Ultravist-370 than with Isovue-370 (0.38% vs 0.24%, P management, the symptoms and signs of 96.5% of the AARs resolved within 24 hours without sequelae.Ultravist-370 and Isovue-370 are safe for patients undergoing enhanced CT scanning. The incidence of AARs is higher with Ultravist-370 than with Isovue-370, but this difference is limited only to the mild AARs. The incidence of AARs could be affected by multiple factors.

Õitsemise tšempionid püsilillepeenral / Kaja Kurg

Index Scriptorium Estoniae

Kurg, Kaja, 1959-

2014-01-01

Helga Taimeaia perenaine Ülli-Riina Sildnik soovitab pikalt õitsvaid püsililli: mandel-piimalill Purpurea, harilik ussitatar, suureõieline iminõges, harilik tõrvalill, Borisi mõõl, kurerehad, siberi iiris, vene ussilakk jt

Languse ajal aitab lühikeseks müük / Tarvo Vaarmets

Index Scriptorium Estoniae

Vaarmets, Tarvo

2008-01-01

Aktsiate hinna langemise ajal soovitab Prantsuse suurpank Societe Generale investoritel teenida languselt. Vt. samas: Lühikeseks müümine; Societe Generale ootab langust erinevate harude ettevõtete aktsiatelt. Diagramm: Saksa ajalehekirjastaja Axel Springeri aktsia hind

Teistmoodi pühadelaud - taimne jõuluroog / Ada Maltseva

Index Scriptorium Estoniae

Maltseva, Ada, 1970-

2007-01-01

Vt. ka Linnaleht : Pärnu 7. dets., lk. B2-B3, Linnaleht : Tartu 7. dets., lk. 10-11. Restorani Aed peakokk Angelica Udeküll soovitab taimetoitlastel jõuluprae valmistamisel vaadata kaunviljade ja tofu poole

Peaminister Parts : lapsed olgu meist targemad / Juhan Parts ; interv. Toomas Sildam

Index Scriptorium Estoniae

Parts, Juhan, 1966-

2003-01-01

Intervjuus tunnistab peaminister Juhan Parts end roheliseks poliitikuks, nimetab valitsusliitu parimaks võimalikuks ja soovitab tudengitel kõigepealt õppida ning annab valitsuse 100 päeva hindeks "neli miinus". Kommenteerivad: Evelyn Sepp, Tarmo Loodus, Ivari Padar

GABA in Paraventricular Nucleus Regulates Adipose Afferent Reflex in Rats.

Directory of Open Access Journals (Sweden)

Lei Ding

Full Text Available Chemical stimulation of white adipose tissue (WAT induces adipose afferent reflex (AAR, and thereby causes a general sympathetic activation. Paraventricular nucleus (PVN is important in control of sympathetic outflow. This study was designed to investigate the role of γ-aminobutyric acid (GABA in PVN in regulating the AAR.Experiments were carried out in anesthetized rats. Renal sympathetic nerve activity (RSNA and mean arterial pressure (MAP were continuously recorded. AAR was evaluated by the RSNA and MAP responses to electrical stimulation of the right epididymal WAT (eWAT afferent nerve. Electrical stimulation of eWAT afferent nerve increase RSNA. Bilateral microinjection of the GABAA receptor agonist isoguvacine or the GABAB receptor agonist baclofen attenuated the AAR. The effect of isoguvacine on the AAR was greater than that of baclofen. The GABAA receptor antagonist gabazine enhanced the AAR, while the GABAB receptor antagonist CGP-35348 had no significant effect on the AAR. Bilateral PVN microinjection of vigabatrin, a selective GABA-transaminase inhibitor, to increase endogenous GABA levels in the PVN abolished the AAR. The inhibitory effect of vigabatrin on the AAR was attenuated by the pretreatment with gabazine or CGP-35348. Pretreatment with combined gabazine and CGP-35348 abolished the effects of vigabatrin.Activation of GABAA or GABAB receptors in the PVN inhibits the AAR. Blockade of GABAA receptors in the PVN enhances the AAR. Endogenous GABA in the PVN plays an important role in regulating the AAR.

Elustiil : kas kapp või garderoob?

Index Scriptorium Estoniae

2008-01-01

Tank Indoor Systems kaubamärki omava Sunorek AS-i juht Priit Pals soovitab kliendi mõõdu järgi valmistatavaid garderoobisüsteeme. Pakutavad tooted: riietumistoad, garderoobisüsteemid, korvisüsteemid, ruumijagajad ja liuguksed

Sõnnikust elektri tootmine on Eesti Energia otsustada / Toivo Tänavsuu

Index Scriptorium Estoniae

Tänavsuu, Toivo

2006-01-01

Seakasvatusfirma Ekseko tahab hakata seasõnnikust elektrit ja soojust tootma, kui Eesti Energia finantseerib projekti. Taani konsultatsioonifirma Energy Consulting Network soovitab rajada koostootmisjaama maksumusega umbes 50-60 miljonit krooni. Lisa: Eesti Energia teeb otsuse lähiajal

Õpetaja muutub õpilaseks / Kenneth Rogoff

Index Scriptorium Estoniae

Rogoff, Kenneth

2008-01-01

USA majandus on hädas, probleemid ületavad tõenäoliselt USA piirid. Ekspertidel tärkavatelt turgudelt ja mujalt on finantskriisidega tegelemise kohta palju öelda ning Ameerika peaks hakkama neid kuulama, soovitab autor

OECD hoiatab kõrge tööpuuduse juurdumise eest. Sellest hakkab sõltuma majanduse kasvujõud / Robert Ford ; intervjueerinud Sirje Rank

Index Scriptorium Estoniae

Ford, Robert

2011-01-01

Intervjuu OECD riigiülevaate üksuse asejuhiga: Eesti suureks probleemiks jääb tööturg, tööjõud on Eestis liiga kõrgelt maksustatud, OECD soovitab alandada makse madalama sissetulekuga sihtgruppidel

Moskva edendab kärmelt omi huve / Kaivo Kopli

Index Scriptorium Estoniae

Kopli, Kaivo

2010-01-01

End Kõrgõzstani valitsusjuhiks kuulutanud Roza Otunbajeva sõnul peab uus valitsus baasileppest USA-ga kinni, väidetavalt soovitab Moskva uuel valitsusel jätta alles vaid Vene baas. Venemaa peaministri Valdimir Putini telefonivestlusest Roza Otumbajevaga

Julgeolekuekspert : unustage jutud Eesti palgaarmeest / Edward N. Luttwak ; interv. Peeter Kuimet

Index Scriptorium Estoniae

Luttwak, Edward N.

2006-01-01

USA julgeolekuanalüütik soovitab Venemaa naabruses oleval Eestil oma riigikaitse üles ehitada Soome eeskujul, ajateenistus peab olema kohustuslik, et vajaduse korral end ise kaitsta, sest NATO abi ei saabu automaatselt. Lisa: Edward Nicolae Luttwak

Nash otvet Tsereteli

Index Scriptorium Estoniae

2006-01-01

Tallinna linnavõimud alustavad tööd Kalevipoja kuju Tallinna lahte püstitamiseks. Skulptuuri autor Tauno Kangro soovitab15 m kõrguse kuju püstitada Lauluväljaku lähedale merre. Insener Paavo Pikandi kommentaarid

The adenosine A2A receptor — Myocardial protectant and coronary target in endotoxemia

Science.gov (United States)

Reichelt, Melissa E.; Ashton, Kevin J.; Tan, Xing Lin; Mustafa, S. Jamal; Ledent, Catherine; Delbridge, Lea M.D.; Hofmann, Polly A.; Headrick, John P.; Morrison, R. Ray

2013-01-01

Background Cardiac injury and dysfunction are contributors to disease progression and mortality in sepsis. This study evaluated the cardiovascular role of intrinsic A2A adenosine receptor (A2AAR) activity during lipopolysaccharide (LPS)-induced inflammation. Methods We assessed the impact of 24 h of LPS challenge (20 mg/kg, IP) on cardiac injury, coronary function and inflammatory mediator levels in Wild-Type (WT) mice and mice lacking functional A2AARs (A2AAR KO). Results Cardiac injury was evident in LPS-treated WTs, with ∼7-fold elevation in serum cardiac troponin I (cTnI), and significant ventricular and coronary dysfunction. Absence of A2AARs increased LPS-provoked cTnI release at 24 h by 3-fold without additional demise of contraction function. Importantly, A2AAR deletion per se emulated detrimental effects of LPS on coronary function, and LPS was without effect in coronary vessels lacking A2AARs. Effects of A2AAR KO were independent of major shifts in circulating C-reactive protein (CRP) and haptoglobin. Cytokine responses were largely insensitive to A2AAR deletion; substantial LPS-induced elevations (up to 100-fold) in IFN-γ and IL-10 were unaltered in A2AAR KO mice, as were levels of IL-4 and TNF-α. However, late elevations in IL-2 and IL-5 were differentially modulated by A2AAR KO (IL-2 reduced, IL-5 increased). Data demonstrate that in the context of LPS-triggered cardiac and coronary injury, A2AAR activity protects myocardial viability without modifying contractile dysfunction, and selectively modulates cytokine (IL-2, IL-5) release. A2AARs also appear to be targeted by LPS in the coronary vasculature. Conclusions These experimental data suggest that preservation of A2AAR functionality might provide therapeutic benefit in human sepsis. PMID:22192288

PR-spetsid annavad Partsile nõu puhata ja analüüsida

Index Scriptorium Estoniae

2005-01-01

TÜ avalikkussuhete õppejõud Kaja Saksakulm-Tampere soovitab Juhan Partsil toimunut analüüsida, suhtekorraldusspetsialist Ivo Rulli arvates oleks Juhan Partsil mõistlik võtta oma edasises avalikus elus pikem paus, taanduda Res Publica esimehe kohalt ja tegutseda parlamendis opositsioonis

Mida vaadata pimedatel öödel? / Andres Maimik

Index Scriptorium Estoniae

Maimik, Andres, 1970-

2006-01-01

Filmirežissöör ja -kriitik soovitab kolme režissööri, kelle filme näidatakse 10. Pimedate Ööde Filmifestivalil : Alex van Warmerdam (Holland), Michael Winterbottom (Suurbritannia) ja Nuri Bilge Ceylan (Türgi)

Lipp lipi peal, lapp lapi peal / Valdo Randpere

Index Scriptorium Estoniae

Randpere, Valdo, 1958-

2006-01-01

IBM Eesti tegevdirektor teeb ettepaneku hakata Tallinna linnal tee- või ummikumaksu koguma, et linna tänavaid korras hoida ning liiklusummikuid hajutada. Ühtlasi soovitab autor teede-tänavate remondi planeerijail olla pisut mõistlikum ja ettenägelikum

Nursipalus võib paugutamine alata ka kohalike loata / Mirko Ojakivi

Index Scriptorium Estoniae

Ojakivi, Mirko

2007-01-01

Kui Nursipalu harjutusväljak Kuperjanovi pataljonile laskeharjutuste korraldamiseks kuulutatakse riiklikult oluliseks objektiks, võib väljaku rajada kohalike inimeste vastuseisust hoolimata. Endine Rõuge vallavanem, parlamendiliige Kalvi Kõva soovitab kaitseministeeriumil elanike arvamusega arvestada. Lisa: Nursipalu harjutusväljaku saaga

Citigroupi soovitus teeb Hansapanga aktsia kuulsaks / Annika Matson

Index Scriptorium Estoniae

Matson, Annika, 1976-

2005-01-01

Maailma suurim pank Citigroup soovitab osta Hansapanga aktsiaid ning kiidab panga kiiret kasvu regioonis ja esmaklassilist juhtimistiimi. Kommenteerivad: Rain Lõhmus, Jüri Mõis, Heldur Meerits. Vt. samas: Ka Leedu Hansabankas tõi hea uudise; Tõnis Oja. Hansapank Wall Streeti suurtegija huviorbiidis

Prantsusmaa on kõigest üks riik, leiavad eurosotsid / Priit Simson

Index Scriptorium Estoniae

Simson Priit, 1977-

2005-01-01

Euroopa Parlamendi sotsialistide juht Martin Schultz on seisukohal, et EL-i põhiseadusleping ei ole Prantsusmaal toimunud referendumi tõttu läbikukkunud, ning soovitab ära oodata leppe heakskiitmise teistes EL-i riikides. Euroopa Parlamendi sotsialistide väljasõiduistungist Tallinnas

Noori õhutatakse osalema videokonkursil / Siim Holvandus

Index Scriptorium Estoniae

Holvandus, Siim

2006-01-01

Üleeuroopalise "Ohutu lähte" konkursi raames toimub alla 19-aastaste filmiamatööride konkurss igat liiki filmidele, muusikavideodele, reklaamiklippidele, mis käsitleksid töö juures esinevaid ohte. Lõuna-Eesti noorte filmifestivali "Flash!" korraldaja Rivo Veski soovitab osaleda

Parkimistasu ja viivistasu - sigakoer Eesti maksumaastikul / Hiie Marrandi, Martin Huberg

Index Scriptorium Estoniae

Marrandi, Hiie

2008-01-01

Parkimistasu aegumisest, viivistasu olemusest ja maksustamisest. Lisatud: Maksumaksja soovitab veel sõiduautode kohta lugeda ; EML selgitustaotlus Maksu- ja Tolliametile ; Kindsigo, Aule. MTA vastus selgitustaotlusele ; Huvitav kokkusattumus ; Lehis, Lasse. Mulle meeldib see! - Vt.: http://www.maksumaksjad.ee/modules/smartsection/item.php?itemid=575.

Kuidas häid kliendisuhteid bilansis näidata? / Andres Root

Index Scriptorium Estoniae

Root, Andres, 1956-

2005-01-01

Kuna viimastel aastakümnetel on äritegevuses silmatorkavalt kasvanud "pehmete" ja "poolpehmete" sisendite tähtsus, siis soovitab AS-i KPMG Baltics audiitor neid vastavalt uutele standarditele IFRS 3 "Äriühendused" ja IAS 38 "Immateriaalsed varad" ka oma bilansis näidata.

Kortermajast saab kena kodu / Mirja Adler

Index Scriptorium Estoniae

Adler, Mirja

2005-01-01

KredExi eluasemevaldkonna juht soovitab kortermaja renoveerimiseks julgelt laenu võtta, kuna see on ehitushindade pideva tõusu tõttu laenuvõtjale lõppkokkuvõttes odavam kui iseseisvalt remondiraha koguda. Tabelid: Kogumise ja laenu hinnatõusu võrdlus; KredExi käenduse maksumus

Villu Reiljan sekkub Looduse Fondi projektide rahastamisse / Tarmo Õuemaa

Index Scriptorium Estoniae

Õuemaa, Tarmo, 1975-

2003-01-01

Keskkonnaministeerium soovitab Keskkonnainvesteeringute Keskusel (KIK) mitte rahastada 7 Eestimaa Looduse Fondi (ELF) projekti, mis on saanud KIK ekspertidelt kõrge hinnangu, ja 2 Rohelise Liikumise projekti. ELF-i tegevjuht Toomas Trapido näeb selle põhjusena ELF-i ja Rohelise Liikumise aktiivset tegevust

Klounaad paukpadrunitega / Andres Ermel

Index Scriptorium Estoniae

Ermel, Andres

2008-01-01

Kaksikvendadest näitekirajnikest Peter ja Anthony Shafferist. Viimase menunäidendist "Nuuskur" ("Sleuth") ja selle järgi 1972. a. Joseph L. Mankewiczi poolt tehtud filmist ning Kenneth Branaghi 2007. a. uusversioonist lühidalt

Aspartic acid racemisation in purified elastin from arteries as basis for age estimation.

Science.gov (United States)

Dobberstein, R C; Tung, S-M; Ritz-Timme, S

2010-07-01

Aspartic acid racemisation (AAR) results in an age-dependent accumulation of D: -aspartic acid in durable human proteins and can be used as a basis for age estimation. Routinely, age estimation based on AAR is performed by analysis of dentine. However, in forensic practise, teeth are not always available. Non-dental tissues for age estimation may be suitable for age estimation based on AAR if they contain durable proteins that can be purified and analysed. Elastin is such a durable protein. To clarify if purified elastin from arteries is a suitable sample for biochemical age estimation, AAR was determined in purified elastin from arteries from individuals of known age (n = 68 individuals, including n = 15 putrefied corpses), considering the influence of different stages of atherosclerosis and putrefaction on the AAR values. AAR was found to increase with age. The relationship between AAR and age was good enough to serve as basis for age estimation, but worse than known from dentinal proteins. Intravital and post-mortem degradation of elastin may have a moderate effect on the AAR values. Age estimation based on AAR in purified elastin from arteries may be a valuable additional tool in the identification of unidentified cadavers, especially in cases where other methods cannot be applied (e.g., no available teeth and body parts).

Assessment of nasal obstruction with rhinomanometry and subjective scales and outcomes of surgical and medical treatment.

Science.gov (United States)

Lara-Sánchez, Hugo; Álvarez Nuño, Candelas; Gil-Carcedo Sañudo, Elisa; Mayo Iscar, Agustín; Vallejo Valdezate, Luis Ángel

Prospective study of patients with nasal obstruction (NO) in order to measure therapeutic success by anterior active rhinomanometry (AAR), Nasal Obstruction Symptom Evaluation (NOSE) scale and Visual Analogue Scale (VAS) and to establish the correlation between these tests. Patients with NO, on whom we performed an AAR, NOSE and VAS scales at baseline and after medical treatment (topical nasal steroid) or surgery (septoplasty, turbinoplasty or septoplasty and turbinoplasty). The nasal flow obtained by the AAR and the score of both subjective scales (NOSE and VAS) were compared and analyzed. A total of 102 patients were included in the study. Surgical treatment resulted in statistically significant differences with the AAR and the subjective scales. While in patients with medical treatment there was an increase in the AAR nasal flow but without statistical significance (P=.1363). The correlation between the AAR, the NOSE and VAS scales was measured finding a strong correlation between the NOSE and VAS scales only (r=.83327). The patients with NO treated surgically have better results when these are evaluated by AAR or with subjective scales. There is no significant correlation between AAR, NOSE and VAS scales, this is considered to be because the AAR and subjective scales are complementary and measure different aspects of NO. The AAR and subjective scales are useful tools to be used together for the follow up of patients with NO. Copyright © 2016 Elsevier España, S.L.U. and Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello. All rights reserved.

Nokia kasum tuli allapoole ootusi / Lauri Matsulevitsh

Index Scriptorium Estoniae

Matsulevitsh, Lauri

2005-01-01

Mobiilitootja Nokia kvartalikasum ei rahuldanud turgu. Tihe konkurents vähendab telefonide müügihinda ja ettevõtte kasumlikkust. Vt. samas: Nokia edaspidi prognoose ei anna; Analüütik soovitab Nokia aktisat müüa. Diagramm: Eilsed tulemused tegid tõusutrendile lõpu

Taking a stroll through the shelves of the History of Estonian Thought / Paavo Matsin

Index Scriptorium Estoniae

Matsin, Paavo, 1970-

2011-01-01

Raamatusarjast "Eesti mõttelugu" (kirj. Ilmamaa). Pikemalt on tutvustatud Uku Masingu artiklikogumikke "Pessimismi põhjendus" (1995) ja "Meil on lootust" (1998), Haljand Udami "Orienditeekonda" (2001) ja Vaino Vahingu "Vaimuhaiguse müüti" (2005). Autor soovitab "Eesti mõtteloo" sarjas välja anda Gunnar Aarma artiklikogumik

Calibration of amino acid racemization (AAR) kinetics in United States mid-Atlantic Coastal Plain Quaternary mollusks using 87Sr/ 86Sr analyses: Evaluation of kinetic models and estimation of regional Late Pleistocene temperature history

Science.gov (United States)

Wehmiller, J.F.; Harris, W.B.; Boutin, B.S.; Farrell, K.M.

2012-01-01

The use of amino acid racemization (AAR) for estimating ages of Quaternary fossils usually requires a combination of kinetic and effective temperature modeling or independent age calibration of analyzed samples. Because of limited availability of calibration samples, age estimates are often based on model extrapolations from single calibration points over wide ranges of D/L values. Here we present paired AAR and 87Sr/ 86Sr results for Pleistocene mollusks from the North Carolina Coastal Plain, USA. 87Sr/ 86Sr age estimates, derived from the lookup table of McArthur et al. [McArthur, J.M., Howarth, R.J., Bailey, T.R., 2001. Strontium isotopic stratigraphy: LOWESS version 3: best fit to the marine Sr-isotopic curve for 0-509 Ma and accompanying Look-up table for deriving numerical age. Journal of Geology 109, 155-169], provide independent age calibration over the full range of amino acid D/L values, thereby allowing comparisons of alternative kinetic models for seven amino acids. The often-used parabolic kinetic model is found to be insufficient to explain the pattern of racemization, although the kinetic pathways for valine racemization and isoleucine epimerization can be closely approximated with this function. Logarithmic and power law regressions more accurately represent the racemization pathways for all amino acids. The reliability of a non-linear model for leucine racemization, developed and refined over the past 20 years, is confirmed by the 87Sr/ 86Sr age results. This age model indicates that the subsurface record (up to 80m thick) of the North Carolina Coastal Plain spans the entire Quaternary, back to ???2.5Ma. The calibrated kinetics derived from this age model yield an estimate of the effective temperature for the study region of 11??2??C., from which we estimate full glacial (Last Glacial Maximum - LGM) temperatures for the region on the order of 7-10??C cooler than present. These temperatures compare favorably with independent paleoclimate information

Interdependence, Reflexivity, Fidelity, Impedance Matching, and the Evolution of Genetic Coding

Science.gov (United States)

Carter, Charles W; Wills, Peter R

2018-01-01

Abstract Genetic coding is generally thought to have required ribozymes whose functions were taken over by polypeptide aminoacyl-tRNA synthetases (aaRS). Two discoveries about aaRS and their interactions with tRNA substrates now furnish a unifying rationale for the opposite conclusion: that the key processes of the Central Dogma of molecular biology emerged simultaneously and naturally from simple origins in a peptide•RNA partnership, eliminating the epistemological utility of a prior RNA world. First, the two aaRS classes likely arose from opposite strands of the same ancestral gene, implying a simple genetic alphabet. The resulting inversion symmetries in aaRS structural biology would have stabilized the initial and subsequent differentiation of coding specificities, rapidly promoting diversity in the proteome. Second, amino acid physical chemistry maps onto tRNA identity elements, establishing reflexive, nanoenvironmental sensing in protein aaRS. Bootstrapping of increasingly detailed coding is thus intrinsic to polypeptide aaRS, but impossible in an RNA world. These notions underline the following concepts that contradict gradual replacement of ribozymal aaRS by polypeptide aaRS: 1) aaRS enzymes must be interdependent; 2) reflexivity intrinsic to polypeptide aaRS production dynamics promotes bootstrapping; 3) takeover of RNA-catalyzed aminoacylation by enzymes will necessarily degrade specificity; and 4) the Central Dogma’s emergence is most probable when replication and translation error rates remain comparable. These characteristics are necessary and sufficient for the essentially de novo emergence of a coupled gene–replicase–translatase system of genetic coding that would have continuously preserved the functional meaning of genetically encoded protein genes whose phylogenetic relationships match those observed today. PMID:29077934

Prodi tahab USA-stiilis eelvalimised Itaaliasse importida ja need võita / Ülle Toode

Index Scriptorium Estoniae

Toode, Ülle, 1969-

2004-01-01

Euroopa Komisjoni kohalt lahkuv Romano Prodi soovitab Itaalias kasutusele võtta USA-stiilis eelvalimised, et nii valimisteks välja selgitada vasaktsentristide peaministrikandidaat ning alustab oma valimiskampaaniat kohe pärast Brüsselist naasmist. Poliitikavaatlejate arvamusi Itaalia valimissüsteemi muutmisest. Lisa: Pooldajad näevad kasu demokraatiale

Elurõõmu pillerkaar / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2007-01-01

Pimedate Ööde filmifestivali ja Tartu linna eestvõttel toimuva Tartu vabaõhu filmifestivali "Tartuff - armastuse mitu nägu" filme ("Ükskord", "Harold ja Maude", "Veenus", "Elsa ja Fred"). Lisaks tutvustus "Hollywoodi klassika : "West Side'i lugu" ja "Tristan Priimägi soovitab : "Loomu poolest metsikud""

Geophysical Investigation of Upper Mantle Anomalies of the Australian-Antarctic Ridge

Science.gov (United States)

Park, S. H.; Choi, H.; Kim, S. S.; Lin, J.

2017-12-01

Australian-Antarctic Ridge (AAR) is situated between the Pacific-Antarctic Ridge (PAR) and Southeast Indian Ridge (SEIR), extending eastward from the Australian-Antarctic Discordance (AAD). Much of the AAR has been remained uncharted until 2011 because of its remoteness and harsh weather conditions. Since 2011, four multidisciplinary expeditions initiated by the Korea Polar Research Institute (KOPRI) have surveyed the little-explored eastern ends of the AAR and investigated the tectonics, geochemistry, and hydrothermal activity of this intermediate spreading system. Recent isotope studies using the new basalt samples from the AAR have led to the new hypothesis of the Southern Ocean mantle domain (SOM), which may have originated from the super-plume activity associated with the Gondwana break-up. In this study, we characterize the geophysics of the Southern Ocean mantle using the newly acquired shipboard bathymetry and available geophysical datasets. First, we computed residual mantle Bouguer gravity anomalies (RMBA), gravity-derived crustal thickness, and residual topography along the AAR in order to obtain a geological proxy for regional variations in magma supply. The results of these analyses revealed that the southern flank of the AAR is associated with shallower seafloor, more negative RMBA, thicker crust, and/or less dense mantle in comparison to the conjugate northern flank. Furthermore, this north-south asymmetry becomes more prominent toward the central ridge segments of the AAR. Interestingly, the along-axis depths of the entire AAR are significantly shallower than the neighboring ridge systems and the global ridges of intermediate spreading rates. Such shallow depths are also correlated with regional negative geoid anomalies. Furthermore, recent mantle tomography models consistently showed that the upper mantle (< 250 km) below the AAR has low S-wave velocities, suggesting that it may be hotter than the nearby ridges. Such regional-scale anomalies of the

Maria Joao Rodrigues : toetage teadust / Maria Joao Rodrigues ; interv. Toivo Tänavsuu

Index Scriptorium Estoniae

Rodrigues, Maria Joao

2004-01-01

Eestis visiidil viibinud Euroopa Komisjoni nõunik soovitab Eestil valida spetsiifilised maksusoodustused, kui Eestil oleks valida üldise maksumäärade alandamise ja spetsiifiliste maksusoodustuste vahel. Üldine maksumäärade alandamine võib tema sõnul löögi alla seada riigieelarve. Lisa: Lissaboni eesmärgid

Valitsuse plaan tõstab kütteõliga kütjate kulusid 133% / Alan Vaht

Index Scriptorium Estoniae

Vaht, Alan, 1976-

2015-01-01

Autor soovitab kütteõliga kütmise kallinemise tõttu investeerida küttesüsteemi väljavahetamisse, soodsaim lahendus oleks asendada senine õliküte kvisöe, turbabriketi, puidubriketi või puidugraanuliga; põrandakütte puhul oleks lahendus maa-vesi või õhk-vesi soojupump

Nordea - investeering tulevikku / Alvar Jõgeva

Index Scriptorium Estoniae

Jõgeva, Alvar

2004-01-01

Autor analüüsib Põhja- ja Baltimaade juhtiva finantskontserni Nordea senist käekäiku, nähes selles üsna stabiilset pikaajalist investeeringut ning prognoosib aktsia hinna kasvu tulevikus. Diagramm: Nordea aktsia alustas tõusutrendi; Kasumile ennustatakse jätkuvat kasvu. Vt. samas: Carnegie soovitab aktsiat osta

Kuidas finantseerida eksporditehinguid / Andrus Treier

Index Scriptorium Estoniae

Treier, Andrus, 1974-

2005-01-01

Enamik riike pakub oma ettevõtetele otseseid või kaudseid toetusi ekspordi edendamiseks. Lisaks sellele soovitab KredEx-i juhataja ettevõtetel teha ekspordikindlustus, millega erakindlustaja või riiklik ekspordikrediidiasutus kindlustab ettevõttele raha laekumise tehingu eest ka juhul, kui ostja teatud põhjusel seda ei tee. Lisa: Riikliku ekspordigarantii eelised

Temporal and spatial characteristics of the area at risk investigated using computed tomography and T1-weighted magnetic resonance imaging

DEFF Research Database (Denmark)

van der Pals, Jesper; Hammer-Hansen, Sophia; Nielles-Vallespin, Sonia

2015-01-01

AIMS: Cardiovascular magnetic resonance (CMR) imaging can measure the myocardial area at risk (AAR), but the technique has received criticism for inadequate validation. CMR commonly depicts an AAR that is wider than the infarct, which in turn would require a lateral perfusion gradient within...... and fluorescent microparticle pathology were used to investigate the AAR in a canine model (n = 10) of ischaemia and reperfusion. AAR size by CMR correlated well with CT (R(2) = 0.80), microsphere blood flow (R(2) = 0.80), and pathology (R(2) = 0.74) with good limits of agreement [-0.79 ± 4.02% of the left.......05 ± 0.02 mL/g/min, lateral vs. core, P = 0.001). The transmural extent of MI was lower in the lateral portion of the AAR than the core (28.2 ± 10.2 vs. 17.4 ± 8.4% of the wall, P = 0.001). CONCLUSION: T1-weighted CMR accurately quantifies size of the AAR with excellent agreement compared with three...

Neighbors uneasy about radioactive waste proposal / Milda Seputyte

Index Scriptorium Estoniae

Seputyte, Milda

2005-01-01

Lätlased on vastu Leedu plaanile rajada Läti-Leedu piiri lähedusse lühiajaliste radioaktiivsete jäätmete ladustuskoht. Läti keskkonnaminister Raimonds Vejonis saatis oma Leedu kolleegile kirja, milles soovitab leida ettevõtmisele teine koht, kuna lähedal asub Läti jaoks strateegiliselt tähtis turismipiirkond

Kes on Eesti Obama? Lihtne küsimus / Raimo Ülavere

Index Scriptorium Estoniae

Ülavere, Raimo, 1970-

2009-01-01

USA president Barack Obama on oma esimese 11 töönädalaga "rääkinud" üles inimeste usu tulevikku. Autor arutleb, kas mõni Eesti ühiskonna liidritest, sealhulgas president, oleks selleks võimeline. Autor näeb lahendust pigem kodanikualgatuses ning soovitab osaleda "Minu Eesti" mõttetalgutel

Free-flying dynamics and control of an astronaut assistant robot based on fuzzy sliding mode algorithm

Science.gov (United States)

Gao, Qing; Liu, Jinguo; Tian, Tongtong; Li, Yangmin

2017-09-01

Space robots can perform some tasks in harsh environment as assistants of astronauts or substitutions of astronauts. Taking the limited working time and the arduous task of the astronauts in the space station into account, an astronaut assistant robot (AAR-2) applied in the space station is proposed and designed in this paper. The AAR-2 is achieved with some improvements on the basis of AAR-1 which was designed before. It can exploit its position and attitude sensors and control system to free flight or hover in the space cabin. And it also has a definite environmental awareness and artificial intelligence to complete some specified tasks under the control of astronauts or autonomously. In this paper, it mainly analyzes and controls the 6-DOF motion of the AAR-2. Firstly, the system configuration of AAR-2 is specifically described, and the movement principles are analyzed. Secondly, according to the physical model of the AAR-2, the Newton - Euler equation is applied in the preparation of space dynamics model of 6-DOF motion. Then, according to the mathematical model's characteristics which are nonlinear and strong coupling, a dual closed loop position and attitude controller based on fuzzy sliding mode control is proposed and designed. Finally, simulation experiments are appropriate to provide for AAR-2 control system by using Matlab/Simulink. From the simulation results it can be observed that the designed fuzzy sliding mode controller can control the 6-DOF motion of AAR-2 quickly and precisely.

Muhamed õpetab eestlasi kallist Tseiloni teed jooma / Andres Reimer

Index Scriptorium Estoniae

Reimer, Andres

2006-01-01

Sri Lanka päritolu ärimees Muhamed Rushdie Muhamed Farouk müüb Eestis kvaliteetset ja hinnalist Tseiloni teed. Farouk taunib paljude Eesti suurkaupluste eelistust töötada üksnes suurte tarnijate ja väikese sortimendiga ning soovitab eestlastel õppida oma elu korraldamisel jaapanlastelt. Kommenteerivad Priit Põiklik ja Kadri Aguraiuja

"Vargamäe kuningriik". "Oscar ja Roosamamma. Kirjad Jumalale" / Tauno Teder

Index Scriptorium Estoniae

Teder, Tauno

2007-01-01

Autor soovitab vaadata Endla ja Rakvere Teatri suvelavastust "Vargamäe kuningriik" A. H. Tammsaare "Tõe ja õiguse" I ja V osa ainetel, lavastajaks Jaanus Rohumaa ning E.-E. Schmitti loo järgi sündinud näidendit "Oscar ja Roosamamma. Kirjad Jumalale". Lavastaja ja peaosas Üllar Saaremäe, Rakvere Teater

RILEM recommendations for the prevention of damage by alkali-aggregate reactions in new concrete structures state-of-the-art report of the RILEM technical committee 219-ACS

CERN Document Server

Sims, Ian

2016-01-01

This book contains the full set of RILEM Recommendations which have been produced to enable engineers, specifiers and testing houses to design and produce concrete which will not suffer damage arising from alkali reactions in the concrete. There are five recommended test methods for aggregates (designated AAR-1 to AAR-5), and an overall recommendation which describes how these should be used to enable a comprehensive aggregate assessment (AAR-0). Additionally, there are two Recommended International Specifications for concrete (AAR-7.1 & 7.2) and a Preliminary International Specification for dams and other hydro structures (AAR-7.3), which describe how the aggregate assessment can be combined with other measures in the design of the concrete to produce a concrete with a minimised risk of developing damage from alkali-aggregate reactions.

Tipologias e Arquétipos: a Psicologia Profunda como base para uma hermenêutica

OpenAIRE

Jactania Marques Muller; Patricia de Sá Freire

2015-01-01

http://dx.doi.org/10.5007/1807-1384.2015v12n1p382FERNANDES, Ermelinda Ganem; FIALHO, Francisco Antônio Pereira. Tipologias e arquétipos: a Psicologia Profunda como base para uma hermenêutica - Coleção Jung sai pra rua. v. 1. Florianópolis: Insular, 2014. 264 p. FERNANDES, Ermelinda Ganem; FIALHO, Francisco Antônio Pereira. Tipologias e arquétipos: a Psicologia Profunda como base para uma hermenêutica - Coleção Jung sai pra rua. v. 1. Florianópolis: Insular, 2014. 264 p. FERNANDES, Ermel...

Ilves calls for end to party politics / Ashley Brettell

Index Scriptorium Estoniae

Brettell, Ashley

2009-01-01

Eesti poliitikas ja majanduses arenevast kriisist. Viidatud on ka president Toomas Hendrik Ilvese intervjuule (President: valitsus võiks koos püsida kriisi madalseisust väljatulekuni, Eesti Päevaleht 9. mai 2009, lk. 4-5), kus riigipea soovitab muuhulgas seada riigi hea käekäik esiplaanile oma erakonna käekäigu ees

Üleilmse finantskriisi leevenemist silmapiiril veel ei paista / Erik Aru

Index Scriptorium Estoniae

Aru, Erik

2007-01-01

Maailma rahaturgudel kestab veel krediidikriis. Mitme vaatleja hinnangul näitab see, et kriis pole lahenenud ka pärast intressimäära langetamist, et tegemist on tõsise probleemiga. Investeerimispanga Goldman Sachs peaökonomist Jan Hatzius soovitab intressi veelgi vähendada. Hinnanguid kahjumi suuruse kohta. Lisad: Pangandus - pidev kriiside allikas; Euroopa keskpankureid inflatsioon ei loksuta

Inhibition of A2A Adenosine Receptor Signaling in Cancer Cells Proliferation by the Novel Antagonist TP455

Directory of Open Access Journals (Sweden)

Stefania Gessi

2017-12-01

Full Text Available Several evidences indicate that the ubiquitous nucleoside adenosine, acting through A1, A2A, A2B, and A3 receptor (AR subtypes, plays crucial roles in tumor development. Adenosine has contrasting effects on cell proliferation depending on the engagement of different receptor subtypes in various tumors. The involvement of A2AARs in human A375 melanoma, as well as in human A549 lung and rat MRMT1 breast carcinoma proliferation has been evaluated in view of the availability of a novel A2AAR antagonist, with high affinity and selectivity, named as 2-(2-furanyl-N5-(2-methoxybenzyl[1,3]thiazolo[5,4-d]pyrimidine-5,7-diammine (TP455. Specifically, the signaling pathways triggered in the cancer cells of different origin and the antagonist effect of TP455 were investigated. The A2AAR protein expression was evaluated through receptor binding assays. Furthermore, the effect of A2AAR activation on cell proliferation at 24, 48 and 72 hours was studied. The selective A2AAR agonist 2-p-(2-carboxyethylphenethylamino-5′-N-ethylcarboxamidoadenosine hydrochloride (CGS21680, concentration-dependently induced cell proliferation in A375, A549, and MRMT1 cancer cells and the effect was potently antagonized by the A2AAR antagonist TP455, as well as by the reference A2AAR blocker 4-(2-[7-amino-2-(2-furyl[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethylphenol (ZM241385. As for the signaling pathway recruited in this response we demonstrated that, by using the specific inhibitors of signal transduction pathways, the effect of A2AAR stimulation was induced through phospholipase C (PLC and protein kinase C-delta (PKC-δ. In addition, we evaluated, through the AlphaScreen SureFire phospho(p protein assay, the kinases enrolled by A2AAR to stimulate cell proliferation and we found the involvement of protein kinase B (AKT, extracellular regulated kinases (ERK1/2, and c-Jun N-terminal kinases (JNKs. Indeed, we demonstrated that the CGS21680 stimulatory effect on kinases was

25-Hydroxyvitamin D, IL-31, and IL-33 in Children with Allergic Disease of the Airways

Directory of Open Access Journals (Sweden)

Anna Bonanno

2014-01-01

Full Text Available Low vitamin D is involved in allergic asthma and rhinitis. IL-31 and IL-33 correlate with Th2-associated cytokines in allergic disease. We investigated whether low vitamin D is linked with circulating IL-31 and IL-33 in children with allergic disease of the airways. 25-Hydroxyvitamin D [25(OH Vit D], IL-31, and IL-33 plasma levels were measured in 28 controls (HC, 11 allergic rhinitis (AR patients, and 35 allergic asthma with rhinitis (AAR patients. We found significant lower levels of 25(OH Vit D in AR and in AAR than in HC. IL-31 and IL-33 plasma levels significantly increased in AAR than HC. IL-31 and IL-33 positively correlated in AR and AAR. 25(OH Vit D deficient AAR had higher levels of blood eosinophils, exacerbations, disease duration, and total IgE than patients with insufficient or sufficient 25(OH Vit D. In AAR 25(OH Vit D levels inversely correlated with total allergen sIgE score and total atopy index. IL-31 and IL-33 did not correlate with 25(OH Vit D in AR and AAR. In conclusion, low levels of 25(OH Vit D might represent a risk factor for the development of concomitant asthma and rhinitis in children with allergic disease of the airways independently of IL-31/IL-33 Th2 activity.

Tants valguse laval / Aili Ermel

Index Scriptorium Estoniae

Ermel, Aili

2013-01-01

Valgustid Milanos toimunud messil "Euroluce 2013". Mihkel Masso ja Johan Tali paberlennukitest inspireeritud laevalgustid "Hetk". Tarmo Luisu valgusti "Spider" ja valgustisari "Toila", Tõnis Vellama valgusti "Aero", Tõnis Vellama ja Kalju Palo seinavalgusti "Retro", Triin Kõivupuu ja Eva Prüüsi valgustisari "Lill"

Derzhat nelzja devalvirovat / Aleksandr Tshaplõgin

Index Scriptorium Estoniae

Tšaplõgin, Aleksandr, 1964-

2007-01-01

Janek Mäggi väitest krooni devalveerumise kohta, Lätis vallandunud dollari- ja euroostupaanikast seoses juttudega lati võimalikust devalvatsioonist. Eesti Panga pressiteenistuse juht Janno Toots on seisukohal, et J. Mäggi ei valda teemat, ning soovitab sellele kõigele mitte tähelepanu pöörata. Heido Vitsur leiab, et nii lati kui ka krooni devalvatsiooni juttude taga on spekulandid

Milline ETF sähvatab uuel aastal? / Fredy-Edwin Esse

Index Scriptorium Estoniae

Esse, Fredy-Edwin

2010-01-01

Sel aastal on kõrgeimat tootlust pakkunud toorainete ja eelkõige väärsimetallide börsil kaubeldavad fondid ehk ETF-id. Aastaga on enim kallinenud toorainete ETF-id, kus suurimad tõusjad on väärismetallid. Autor soovitab arenevatest turgudest enim tähelepanu pöörata Venemaale. LHV Panga portfellihalduri-fondijuhi abi Joel Kukemelki kommentaare

John Berry : rahvuse kaardile mängimine toob tõsiseid tagajärgi / John Berry ; interv. Raivo Vetik

Index Scriptorium Estoniae

Berry, John

2007-01-01

Kanada emeriitprofessor rahvuslikust turvatundest, sobivast nimetusest mitte-eestlaste kohta, pronkssõduri teisaldamisest, Venemaaga suhtlemisest, ajaloosündmuste erinevast mõtestamisest, sh. ka Kanadas; kakskeelsusest, muukeelse eestimeelsuse võimalikkusest. Professori sõnul saab ajaloosündmusi õpetada nii, et näidatakse nende erinevaid tõlgendusi, ta soovitab õpetada mõlemaid käsitlusi ja lasta õpilastel mõtiskleda erinevuste üle

Miks Eesti soost Steve Jurvetson peab nanotehnoloogiat järgmiseks suureks asjaks / Richard Waters ; tõlk. Erik Aru

Index Scriptorium Estoniae

Waters, Richard

2005-01-01

Steve Jurvetsoni hinnangul muutuvad nanotehnoloogilise revolutsiooni tulemused nähtavaks järgmise 3-5 aasta jooksul. Ettevõtjatel soovitab ta mitte karta mõelda suurelt ja oodata tulevikku, mis võib veel praegu näida fantastiline. Tema sõnul on Interneti ajalugu juba jõudnud punkti, kus äri muutvad sündmused on saamas reaalsuseks. Lisa: Steve Jurvetsoni tulevikuvisioon

Preclinical evaluation of a 68Ga-labeled biotin analogue for applications in islet transplantation

International Nuclear Information System (INIS)

Eriksson, Olof; Carlsson, Fredrik; Blom, Elisabeth; Sundin, Anders; Långström, Bengt; Korsgren, Olle; Velikyan, Irina

2012-01-01

Introduction: Islet transplantation is a promising treatment for type 1 diabetes mellitus, but the fate of the cells after intraportal infusion is unclear. It is therefore imperative to develop novel techniques for noninvasive imaging and quantification of events following islet transplantation. Methods: Small islet-like microbeads, avidin-covered agarose resins (AARs), were used as a model system for islet transplantation. Capability for specific [ 68 Ga]Ga-DOTA-(PEG) 2 -biotin uptake and retention for either AARs or human islets conjugated with avidin by means of a heparin scaffold was studied in vitro. Biodistribution of the novel positron emission tomography (PET) tracer [ 68 Ga]Ga-DOTA-(PEG) 2 -biotin was evaluated in mice treated by intraportal transplantation of AARs by μPET/computed tomography and ex vivo organ distribution and compared with control mice. Results: AARs had high capability to bind [ 68 Ga]Ga-DOTA-(PEG) 2 -biotin, close to 50% of administrated tracer/μl in vitro (>0.25 MBq/μl). Avidin-tagged human islets could bind on average 2.2% of administered tracer/μl. Specificity (>90%) and retention (>90% after 1 h) were high for both AARs and avidin-tagged islets. Hepatic tracer uptake and retention were increased in mice transplanted with AARs [standardized uptake value (SUV)=2.6] compared to the untreated group (SUV=1.4). In vivo uptake of tracer to AARs was blocked by preadministration of unlabeled biotin. Conclusions: Avidin-tagged islet-like objects can be tracked in hepatic volume after intraportal transplantation by using [ 68 Ga]Ga-DOTA-(PEG) 2 -biotin and PET.

"La sécurité énergétique de l'Europe est un défi politique" / Toomas Hendrik Ilves ; interv. Laure Mandeville

Index Scriptorium Estoniae

Ilves, Toomas Hendrik, 1953-

2008-01-01

President Toomas Hendrik Ilves räägib kohtumisest Prantsusmaa presidendi Nicolas Sarkozy'ga, NATO tippkohtumisest Bukarestis, vajadusest aidata Ukrainat ja Gruusiat demokraatia arendamisel ja NATOsse pääsemisel, ootustest Prantsusmaa suhtes Euroopa Liidu eesistujaperioodil, Euroopa Liidu energiajulgeolekust ja ühisest energiapoliitikast, Eesti ja Venemaa suhetest. Riigipea soovitab suhtlemisel Venemaaga heasoovlikku ükskõiksust. Vabariigi President töövisiidil Pariisis 6.-8.04.2008

Chapter K: Progress in the Evaluation of Alkali-Aggregate Reaction in Concrete Construction in the Pacific Northwest, United States and Canada

Science.gov (United States)

Shrimer, Fred H.

2005-01-01

The supply of aggregates suitable for use in construction and maintenance of infrastructure in western North America is a continuing concern to the engineering and resources-management community. Steady population growth throughout the region has fueled demand for high-quality aggregates, in the face of rapid depletion of existing aggregate resources and slow and difficult permitting of new sources of traditional aggregate types. In addition to these challenges, the requirement for aggregates to meet various engineering standards continues to increase. In addition to their physical-mechanical properties, other performance characteristics of construction aggregates specifically depend on their mineralogy and texture. These properties can result in deleterious chemical reactions when aggregate is used in concrete mixes. When this chemical reaction-termed 'alkali-aggregate reaction' (AAR)-occurs, it can pose a major problem for concrete structures, reducing their service life and requiring expensive repair or even replacement of the concrete. AAR is thus to be avoided in order to promote the longevity of concrete structures and to ensure that public moneys invested in infrastructure are well spent. Because the AAR phenomenon is directly related to the mineral composition, texture, and petrogenesis of the rock particles that make up aggregates, an understanding of the relation between the geology and the performance of aggregates in concrete is important. In the Pacific Northwest, some aggregates have a moderate to high AAR potential, but many others have no or only a low AAR potential. Overall, AAR is not as widespread or serious a problem in the Pacific Northwest as in other regions of North America. The identification of reactive aggregates in the Pacific Northwest and the accurate prediction of their behavior in concrete continue to present challenges for the assessment and management of geologic resources to the owners and operators of pits and quarries and to the

Arnold Rüütlile tuleb anda võimalus rääkida / Jarno Laur

Index Scriptorium Estoniae

Laur, Jarno, 1975-

2006-01-01

Autori arvates on ebaaus nii ametisoleva presidendi Arnold Rüütli, presidenti valivate saadikute ja volinike kui ka teiste presidendikandidaatide suhtes, et praegust presidenti pole sisulistesse debattidesse üldse kaasatud. Ta soovitab lisaks Rahvaliidu 16. allkirjale anda kõigil teistel parlamendierakondadel vähemalt üks allkiri president Rüütli toetuseks, et viimane saaks võimaluse rääkida ning osaleda valimiskampaanias teistega võrdsetel alustel

Kirjanik soovitab / Olavi Ruitlane

Index Scriptorium Estoniae

Ruitlane, Olavi, 1969-

2009-01-01

Tutvustus: Volkonski, Peeter. ISBN 978-9985-9980-6-9. Tallinn : Menu Kirjastus, 2009 ; Preussler, Otfried. Krabat / saksa keelest tõlkinud Linda Ariva. [Tallinn] : Tänapäev, 2009 ; Teede, Andra. Atlas : [luuletused]. Pärnu : Jumalikud Ilmutused, 2009 ; Wiedemann, Vladimir. Maagide kool. Eesti okultne underground 1970-1980. Tartu : Hotpress, 2008

Kirjanik soovitab / Heiki Vilep

Index Scriptorium Estoniae

Vilep, Heiki, 1960-

2009-01-01

Tutvustus: Pratt, David. Võimatu nõuab rohkem aega : 1000 tarkusetera Nobeli preemia laureaadilt / inglise keelest tõlkinud Marge Paal. [Tallinn] : Ersen, 2009 ; Varblane, Hannes. Taarnateel : katsetusi 1967–1970 : [luuletused]. Tartu : Ilmamaa, 2009 ; Eesti muinasjuttude kuldraamat / koostanud Reet Krusten. Tallinn : TEA Kirjastus, 2009 ; Eco, Umberto. Kuus jalutuskäiku kirjandusmetsades / inglise keelest tõlkinud Ene-Reet Soovik. Tallinn : Varrak, 2009

Psychophysiological Assessment in Pilots Performing Challenging Simulated and Real Flight Maneuvers.

Science.gov (United States)

Johannes, Bernd; Rothe, Stefanie; Gens, André; Westphal, Soeren; Birkenfeld, Katja; Mulder, Edwin; Rittweger, Jörn; Ledderhos, Carla

2017-09-01

The objective assessment of psychophysiological arousal during challenging flight maneuvers is of great interest to aerospace medicine, but remains a challenging task. In the study presented here, a vector-methodological approach was used which integrates different psychophysiological variables, yielding an integral arousal index called the Psychophysiological Arousal Value (PAV). The arousal levels of 15 male pilots were assessed during predetermined, well-defined flight maneuvers performed under simulated and real flight conditions. The physiological data, as expected, revealed inter- and intra-individual differences for the various measurement conditions. As indicated by the PAV, air-to-air refueling (AAR) turned out to be the most challenging task. In general, arousal levels were comparable between simulator and real flight conditions. However, a distinct difference was observed when the pilots were divided by instructors into two groups based on their proficiency in AAR with AWACS (AAR-Novices vs. AAR-Professionals). AAR-Novices had on average more than 2000 flight hours on other aircrafts. They showed higher arousal reactions to AAR in real flight (contact: PAV score 8.4 ± 0.37) than under simulator conditions (7.1 ± 0.30), whereas AAR-Professionals did not (8.5 ± 0.46 vs. 8.8 ± 0.80). The psychophysiological arousal value assessment was tested in field measurements, yielding quantifiable arousal differences between proficiency groups of pilots during simulated and real flight conditions. The method used in this study allows an evaluation of the psychophysiological cost during a certain flying performance and thus is possibly a valuable tool for objectively evaluating the actual skill status of pilots.Johannes B, Rothe S, Gens A, Westphal S, Birkenfeld K, Mulder E, Rittweger J, Ledderhos C. Psychophysiological assessment in pilots performing challenging simulated and real flight maneuvers. Aerosp Med Hum Perform. 2017; 88(9):834-840.

Cluster in the Auroral Acceleration Region

Science.gov (United States)

Pickett, Jolene S.; Fazakerley, Andrew N.; Marklund, Gorun; Dandouras, Iannis; Christopher, Ivar W.; Kistler, Lynn; Lucek, Elizabeth; Masson, Arnaud; Taylor, Matthew G.; Mutel, Robert L.;

Variations in the Spatial Distribution of Gall Bladder Cancer: A Call ...

African Journals Online (AJOL)

adjusted incidence rates (AAR) of certain cancers in specific geographical regions within ... which is second to the highest (Chile) in the world and AAR of carcinoma gall bladder .... Conflict of Interest: None declared. 4. Asmarian NS, Ruzitalab ...

Extracellular Synthesis and Characterization of Gold Nanoparticles Using Mycobacterium sp. BRS2A-AR2 Isolated from the Aerial Roots of the Ghanaian Mangrove Plant, Rhizophora racemosa.

Science.gov (United States)

Camas, Mustafa; Sazak Camas, Anil; Kyeremeh, Kwaku

2018-06-01

Through the use of genomes that have undergone millions of years of evolution, marine Actinobacteria are known to have adapted to rapidly changing environmental pressures. The result is a huge chemical and biological diversity among marine Actinobacteria . It is gradually becoming a known fact that, marine Actinobacteria have the capability to produce nanoparticles which have reasonable sizes and structures with possible applications in biotechnology and pharmacology. Mycobacterium sp. BRS2A-AR2 was isolated from the aerial roots of the mangrove plant Rhizophora racemosa . The Mycobacterium was demonstrated for the first time ever to produce AuNPs with sizes that range between 5 and 55 nm. The highest level absorbance of the biosynthesized AuNPs was typical for actinobacterial strains (2.881 at 545 nm). The polydispersity index was measured as 0.207 in DLS and the zeta potential was negatively charged (- 28.3 mV). Significant vibration stretches were seen at 3314, 2358, 1635 and 667 cm -1 in FT-IR spectra. This demonstrated the possible use of small aliphatic compounds containing -COOH, -OH, -Cl and -NH 2 functional groups in the stabilization of the AuNPs. The effect of the biosynthesized AuNPs on HUVEC and HeLA cell lines was measured at 48 h. IC 50 values were determined at 3500 µg/ml concentration for HUVEC and HeLA cell lines at 45.25 and 53.41% respectively.

Evaluation of the effects of an arm artifact reduction filter in computed tomography

International Nuclear Information System (INIS)

Nozaki, Fumie; Ohno, Hajime; Hirako, Tetsuya

2002-01-01

While performing CT during arterial portography (CTAP) or CT arteriography (CTA), we have instructed patients to in order to reduce streak artifacts. However the repetitive raising and lowering their arms has made it difficult to keep a clean zone and as well as to maintain the position of a target organ. An arm artifact reduction (AAR) filter developed by GE Yokokawa Medical System has been reported to be useful for reducing streak artifacts in CTAP and CTA. The purpose of this study was to estimate the effectiveness of the AAR filter in terms of artifact reduction ratio, CT value, standard deviation and spatial resolution. The use of an AAR filter reduced streak artifacts on images by 15-22% compared with those on images obtained by without the use of the filter and limited deterioration of spatial resolution to within 1%. Moreover, CT value in examination using AAR filter showed no significant change compared with that in non-filter's examination. It is concluded that the use of an AAR filter reduces the burden for the patient and increase the accuracy and flexibility of CT examination while minimizing the reduction in the image quality in CTAP and CTA. (author)

Amino acid repeats avert mRNA folding through conservative substitutions and synonymous codons, regardless of codon bias

Directory of Open Access Journals (Sweden)

Sailen Barik

2017-12-01

Full Text Available A significant number of proteins in all living species contains amino acid repeats (AARs of various lengths and compositions, many of which play important roles in protein structure and function. Here, I have surveyed select homopolymeric single [(An] and double [(ABn] AARs in the human proteome. A close examination of their codon pattern and analysis of RNA structure propensity led to the following set of empirical rules: (1 One class of amino acid repeats (Class I uses a mixture of synonymous codons, some of which approximate the codon bias ratio in the overall human proteome; (2 The second class (Class II disregards the codon bias ratio, and appears to have originated by simple repetition of the same codon (or just a few codons; and finally, (3 In all AARs (including Class I, Class II, and the in-betweens, the codons are chosen in a manner that precludes the formation of RNA secondary structure. It appears that the AAR genes have evolved by orchestrating a balance between codon usage and mRNA secondary structure. The insights gained here should provide a better understanding of AAR evolution and may assist in designing synthetic genes.

Amino acid repeats avert mRNA folding through conservative substitutions and synonymous codons, regardless of codon bias.

Science.gov (United States)

Barik, Sailen

2017-12-01

A significant number of proteins in all living species contains amino acid repeats (AARs) of various lengths and compositions, many of which play important roles in protein structure and function. Here, I have surveyed select homopolymeric single [(A)n] and double [(AB)n] AARs in the human proteome. A close examination of their codon pattern and analysis of RNA structure propensity led to the following set of empirical rules: (1) One class of amino acid repeats (Class I) uses a mixture of synonymous codons, some of which approximate the codon bias ratio in the overall human proteome; (2) The second class (Class II) disregards the codon bias ratio, and appears to have originated by simple repetition of the same codon (or just a few codons); and finally, (3) In all AARs (including Class I, Class II, and the in-betweens), the codons are chosen in a manner that precludes the formation of RNA secondary structure. It appears that the AAR genes have evolved by orchestrating a balance between codon usage and mRNA secondary structure. The insights gained here should provide a better understanding of AAR evolution and may assist in designing synthetic genes.

Structure-Activity Relationships of Truncated C2- or C8-Substituted Adenosine Derivatives as Dual Acting A2A and A3 Adenosine Receptor Ligands

Science.gov (United States)

Hou, Xiyan; Majik, Mahesh S.; Kim, Kyunglim; Pyee, Yuna; Lee, Yoonji; Alexander, Varughese; Chung, Hwa-Jin; Lee, Hyuk Woo; Chandra, Girish; Lee, Jin Hee; Park, Seul-gi; Choi, Won Jun; Kim, Hea Ok; Phan, Khai; Gao, Zhan-Guo; Jacobson, Kenneth A.; Choi, Sun; Lee, Sang Kook; Jeong, Lak Shin

2011-01-01

Truncated N6-substituted-4′-oxo- and 4′-thioadenosine derivatives with C2 or C8 substitution were studied as dual acting A2A and A3 adenosine receptor (AR) ligands. The lithiation-mediated stannyl transfer and palladium-catalyzed cross coupling reactions were utilized for functionalization of the C2 position of 6-chloropurine nucleosides. An unsubstituted 6-amino group and a hydrophobic C2 substituent were required for high affinity at the hA2AAR, but hydrophobic C8 substitution abolished binding at the hA2AAR. However, most of synthesized compounds displayed medium to high binding affinity at the hA3AR, regardless of C2 or C8 substitution, and low efficacy in a functional cAMP assay. Several compounds tended to be full hA2AAR agonists. C2 substitution probed geometrically through hA2AAR-docking, was important for binding in order of hexynyl > hexenyl > hexanyl. Compound 4g was the most potent ligand acting dually as hA2AAR agonist and hA3AR antagonist, which might be useful for treatment of asthma or other inflammatory diseases. PMID:22142423

Mööbel suvekodusse / Aili Ermel

Index Scriptorium Estoniae

Ermel, Aili

2008-01-01

2008. a. Milano messil "Salone Internazionale del Mobile" oli mööblit, mis projekteeritud ekstra õuele, aga oli ka sellist, mis sobib suvel õue ja talvel tuppa. Mööbel firmalt Cappellini, Gervason (disainer Paola Navone), Horm (disainer Mario Bellini), Zanotta (disainerid Gae Aulenti, Prospero Rasulo, Emaf Progetti, Roberto Barbieri), EMU (disainer Patricia Urquiola), Moroso (disainerid Nipa Doshi, Jonhatan Levien, Edward Van Vliet), Cassina (Tokujin Yoshioka) ja RODA. 14 värv. ill

Myocardial area at risk after ST-elevation myocardial infarction measured with the late gadolinium enhancement after scar remodeling and T2-weighted cardiac magnetic resonance imaging

DEFF Research Database (Denmark)

Lønborg, Jacob; Engstrøm, Thomas; Mathiasen, Anders B

2011-01-01

To evaluate the myocardial area at risk (AAR) measured by the endocardial surface area (ESA) method on late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) when applied after scar remodeling (3 months after index infarction) compared to T2-weighted CMR imaging. One hundred...... and sixty nine patients with ST-elevation myocardial infarction, treated with primary percutaneous coronary intervention, underwent one CMR within 1 week after index treatment to determine the AAR with T2-weighted imaging and a second scan 3 months after to measure AAR with the ESA method...

Myocardial area at risk after ST-elevation myocardial infarction measured with the late gadolinium enhancement after scar remodeling and T2-weighted cardiac magnetic resonance imaging

DEFF Research Database (Denmark)

Lønborg, Jacob; Engstrøm, Thomas; Mathiasen, Anders B

2012-01-01

To evaluate the myocardial area at risk (AAR) measured by the endocardial surface area (ESA) method on late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) when applied after scar remodeling (3 months after index infarction) compared to T2-weighted CMR imaging. One hundred...... and sixty nine patients with ST-elevation myocardial infarction, treated with primary percutaneous coronary intervention, underwent one CMR within 1 week after index treatment to determine the AAR with T2-weighted imaging and a second scan 3 months after to measure AAR with the ESA method...

78 FR 75573 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

Science.gov (United States)

2013-12-12

..., facsimile number (202) 646-3347, or email address [email protected] (HSEEP) After Action Report (AAR) Improvement Plan (IP). Type of Information Collection: Revision of a... Exercise and Evaluation Program (HSEEP) After Action Report (AAR) Improvement Plan (IP). Abstract: The...

GPCR Interaction: 30 [GRIPDB[Archive

Lifescience Database Archive (English)

Full Text Available ernalize upon exposure to the agonist. Oxymetazoline (alpha1aAR selective agonist) induces the cointernali...zation of the alpha1aAR and alpha1bAR, whereas the alpha1bAR does not cointernalize

Uljas ja uudishimulik 20-aastane / Madli Pesti

Index Scriptorium Estoniae

Pesti, Madli, 1980-

2007-01-01

VAT Teatri lavastustest - Amélie Nothombi romaani järgi "Vaenlase kosmeetika" (lav. Peeter Raudsepp), Kristof Magnussoni "Meeste varjupaik" (lav. Christian Römer), Hans Christian Anderseni järgi "Merineitsi" (lav. Aare Toikka) ja Urmas Vadi "Elvis oli kapis" (lav. Aare Toikka)

Acute antibody-mediated rejection of skin grafts without involvement of granulocytes or complement

International Nuclear Information System (INIS)

Bogman, M.J.; Cornelissen, I.M.; Koene, R.A.

1984-01-01

In immunosuppressed mice that carry rat skin xeno-grafts, acute antibody-mediated graft rejection (AAR) can be induced by intravenous administration of mouse anti-rat globulin. Dependent on the amount of antibody injected and on the complement status of the recipient, an Arthus-like or a Shwartzman-like pattern of vasculitis occurs. The role of polymorphonuclear granulocytes (PMNs) in either type of vasculitis was tested by inducing AAR in recipients depleted of PMNs by total body irradiation. Despite the absence of PMNs in the graft vessels, AAR occurred both in the Arthus-like and in the Shwartzman-like type. Moreover, AAR could be elicited in PMN-depleted recipients that were complement-depleted by cobra venom factor treatment or were congenitally C5-deficient. We conclude that neither the PMN nor complement is an essential mediator the PMN nor complement is an essential mediator in this form of antibody-mediated vasculitis

GPCR Interaction: 35 [GRIPDB[Archive

Lifescience Database Archive (English)

Full Text Available and alpha2aAR form robust hetero dimer in HEK-293 cells. An interaction between beta1AR and alpha2aAR is reg...ulated by glycosylation. The interaction may play a key role in cross-talk and mu

Azacitidine for Front-Line Therapy of Patients with AML: Reproducible Efficacy Established by Direct Comparison of International Phase 3 Trial Data with Registry Data from the Austrian Azacitidine Registry of the AGMT Study Group

Directory of Open Access Journals (Sweden)

Lisa Pleyer

2017-02-01

Full Text Available We recently published a clinically-meaningful improvement in median overall survival (OS for patients with acute myeloid leukaemia (AML, >30% bone marrow (BM blasts and white blood cell (WBC count ≤15 G/L, treated with front-line azacitidine versus conventional care regimens within a phase 3 clinical trial (AZA-AML-001; NCT01074047; registered: February 2010. As results obtained in clinical trials are facing increased pressure to be confirmed by real-world data, we aimed to test whether data obtained in the AZA-AML-001 trial accurately represent observations made in routine clinical practice by analysing additional AML patients treated with azacitidine front-line within the Austrian Azacitidine Registry (AAR; NCT01595295; registered: May 2012 and directly comparing patient-level data of both cohorts. We assessed the efficacy of front-line azacitidine in a total of 407 patients with newly-diagnosed AML. Firstly, we compared data from AML patients with WBC ≤ 15 G/L and >30% BM blasts included within the AZA-AML-001 trial treated with azacitidine (“AML-001” cohort; n = 214 with AAR patients meeting the same inclusion criteria (“AAR (001-like” cohort; n = 95. The current analysis thus represents a new sub-analysis of the AML-001 trial, which is directly compared with a new sub-analysis of the AAR. Baseline characteristics, azacitidine application, response rates and OS were comparable between all patient cohorts within the trial or registry setting. Median OS was 9.9 versus 10.8 months (p = 0.616 for “AML-001” versus “AAR (001-like” cohorts, respectively. Secondly, we pooled data from both cohorts (n = 309 and assessed the outcome. Median OS of the pooled cohorts was 10.3 (95% confidence interval: 8.7, 12.6 months, and the one-year survival rate was 45.8%. Thirdly, we compared data from AAR patients meeting AZA-AML-001 trial inclusion criteria (n = 95 versus all AAR patients with World Health Organization (WHO-defined AML (“AAR

49 CFR 1135.1 - Quarterly adjustment.

Science.gov (United States)

2010-10-01

... subsequent amendments thereto. In addition, the AAR shall calculate the productivity-adjusted RCAF as..., the Association of American Railroads (AAR) shall calculate and file with the Board by the fifth day... all-inclusive index of railroad costs and calculate and file the RCAF unadjusted for changes in...

Using Rapid Improvement Events for Disaster After-Action Reviews: Experience in a Hospital Information Technology Outage and Response.

Science.gov (United States)

Little, Charles M; McStay, Christopher; Oeth, Justin; Koehler, April; Bookman, Kelly

2018-02-01

The use of after-action reviews (AARs) following major emergency events, such as a disaster, is common and mandated for hospitals and similar organizations. There is a recurrent challenge of identified problems not being resolved and repeated in subsequent events. A process improvement technique called a rapid improvement event (RIE) was used to conduct an AAR following a complete information technology (IT) outage at a large urban hospital. Using RIE methodology to conduct the AAR allowed for the rapid development and implementation of major process improvements to prepare for future IT downtime events. Thus, process improvement methodology, particularly the RIE, is suited for conducting AARs following disasters and holds promise for improving outcomes in emergency management. Little CM , McStay C , Oeth J , Koehler A , Bookman K . Using rapid improvement events for disaster after-action reviews: experience in a hospital information technology outage and response. Prehosp Disaster Med. 2018;33(1):98-100.

Aneurisma da Artéria Renal: cirurgia renal ex-vivo - a propósito de um caso clínico Renal Artery Aneurysm: ex-vivo repair - a case report

Directory of Open Access Journals (Sweden)

Clara Nogueira

2012-09-01

Full Text Available Os aneurismas da artéria renal (AAR são raros, frequentemente assintomáticos, de etiologia variada, frequentemente secundários a aterosclerose e anomalias congénitas. Os AAR com diâmetro superior a 2 cm têm indicação cirúrgica. A escolha da técnica cirúrgica depende da localização anatómica e complexidade do AAR, bem como do tempo previsível de isquemia renal. Os autores descrevem um caso de auto-transplante renal, para tratamento de dois AAR complexos.Renal artery aneurysms (RAA are rare, frequently asymptomatic, with variable etiology, frequently due to atherosclerosis and congenital anomalies. Surgical treatment is indicated for RAA with a diameter greater to 2 cm. Surgical technique will depend on RAA anatomic localization and complexity, as well as, predicted renal isquemic time. The authors report an auto-transplant for treatment of two complex RAA.

Clinical value of spleen acoustic radiation force impulse, aspartate aminotransferase-to-platelet ratio index, and aspartate aminotransferase/alanine aminotransferase ratio in predicting esophageal varices in patients with liver cirrhosis

Directory of Open Access Journals (Sweden)

ZHANG Dakun

2018-03-01

Full Text Available ObjectiveTo investigate the spleen stiffness of patients with chronic hepatitis and liver cirrhosis by spleen acoustic radiation force impulse (ARFI, aspartate aminotransferase-to-platelet ratio index (APRI, and aspartate aminotransferase/alanine aminotransferase ratio (AAR, as well as the clinical value of these three noninvasive techniques in predicting esophageal varices (EV in patients with liver cirrhosis. MethodsA total of 247 patients with chronic hepatitis and liver cirrhosis were enrolled, and ARFI was used to measure real-time spleen stiffness. APRI and AAR were calculated. Gastroscopy was performed within one week before and after measurement to clarify the degree of EV. With the results of gastroscopy as the gold standard, the receiver operating characteristic (ROC curve was used to compare the clinical value of spleen ARFI value, APRI, and AAR in the diagnosis of EV in patients with liver cirrhosis. The t-test was used for comparison of continuous data between two groups. ResultsThere were significant differences between the EV group (n=169 and the non-EV group (n=78 in spleen ARFI stiffness (3.64±0.53 m/s vs 2.97±0.65 m/s, t=-7.93, P＜0.001, APRI (0.87±091 vs 0.52±0.80, t=-2.90, P=0.004, and AAR (1.54±0.67 vs 1.29±0.55, t=-2.93, P=0.004. Spleen ARFI, APRI, and AAR had an area under the ROC curve of 0.80, 0.72, and 0.63, respectively, in predicting EV in patients with liver cirrhosis, there was a significant difference between spleen ARFI stiffness and AAR (P=0.005, while there was no significant difference between spleen ARFI stiffness and APRI (P=0.10. ConclusionARFI is a real-time ultrasound elastography technique, and compared with APRI and AAR, spleen stiffness measured by ARFI can predict EV in patients with chronic hepatitis and liver cirrhosis more accurately and noninvasively and thus holds promise for clinical application.

Riskirühmad Eesti tööjõuturul / Kerstin Peterson

Index Scriptorium Estoniae

Peterson, Kerstin

2005-01-01

Sotsiaalministeeriumi tööturu osakonna peaspetsialisti väitel on Eestile iseloomulik struktuurne töötus, kus töötute haridus, eriala ning oskused ei vasta tööturu nõudmistele. Autor iseloomustab peamisi riskirühmi ning soovitab töötuid käsitleda mitte niivõrd probleemina vaid pigem võimalusena. Diagramm: Töötuse määr regiooniti 2005 II kvartal, %. Lisa: [Riskirühmad Eesti tööturul

Arhitektuurivõistlused 2001 / Tiina Tammet

Index Scriptorium Estoniae

Tammet, Tiina, 1971-

2001-01-01

Samas "Europan 6" (I preemia Tallinnas: H. Götz, S. Lippardt, M. Jensch ja Tartus: J. Vuorinen, E. Kangas; II preemia Viinis: S. Vallner, O. Kadarik, K. Koov, R. Valner), Narva keskosa planeeringu (I - I. Raukas, T. Tammis, T. Teedumäe), Pärnu vanalinna põhikooli juurdeehituse (II - O. Kadarik, M. Tüür), Pärnu Kontserdimaja (I - H. Grossschmidt, K. Koov, K. Nõmm), Tallinna 21. keskkooli renoveerimise (I - R. Järg, T. Korb), Eesti lähimineviku okupatsioonide muuseumi (I - S. Vallner, I. Peil), Võru Võidu väljaku pargi kujunduse (I-II - P. Müüripeal; V. Tomiste ja V. Valk), nukuteatri sisekujunduse (I - R. Kotov, A. Kõresaar), Eurovisiooni lavakujunduse (I - H. Ermel, A. Nurmela, Ü. Mark) arhitektuurivõistluse tulemused.

An analysis of root cause identification and continuous quality improvement in public health H1N1 after-action reports.

Science.gov (United States)

Singleton, Christa-Marie; Debastiani, Summer; Rose, Dale; Kahn, Emily B

2014-01-01

To identify the extent to which the Homeland Security Exercise and Evaluation Program's (HSEEP) After Action Report/Improvement Plan (AAR/IP) template was followed by public health entities and facilitated the identification of detailed corrective actions and continuous improvement. Data were drawn from the US H1N1 Public Health Emergency Response (PHER) federal grant awardees (n = 62). After action report/improvement plan text was examined to identify the presence of AAR/IP HSEEP elements and characterized as "minimally complete," "partially complete," or "complete." Corrective actions (CA) and recommendations within the IP focusing on performance deficits were coded as specific, measurable, and time-bound, and whether they were associated with a problem that met root cause criteria and whether the CA/recommendation was intended to address or fix the root cause. A total of 2619 CA/recommendations were identified. More than half (n = 1480, 57%) addressed root causes. Corrective actions/recommendations associated with complete AARs more frequently addressed root cause (58% vs 51%, χ = 9.1, P < 0.003) and were more specific (34% vs 23%, χ = 32.3, P < 0.0001), measurable (30% vs 18%, χ = 37.9, P < 0.0001), and time-bound (38% vs 15%, χ = 115.5, P < 0.0001) than partially complete AARs. The same pattern was not observed with completeness of IPs. Corrective actions and recommendations were similarly specific and measurable. Recommendations significantly addressed root cause more than CAs. Our analysis indicates a possible lack of awardee distinction between CA and recommendations in AARs. As HSEEP adapts to align with the 2011 National Preparedness Goal and National Preparedness System, future HSEEP documents should emphasize the importance of root cause analysis as a required element within AAR documents and templates in the exercise and real incident environment, as well as the need for specific and measurable CAs.

Parimaid õpetajaid näeb taas terve Eesti / Sirje Pärismaa

Index Scriptorium Estoniae

Pärismaa, Sirje, 1958-

2014-01-01

Üleriigilise üldhariduse tunnustussüsteemi „Eestimaa õpib ja tänab“ tänuüritusest, kus pälvisid auhinna aasta klassijuhataja Aare Veedla, Luua Metsanduskooli õpetaja Aino Mölder, Hugo Treffneri Gümnaasiumi õpetaja Aare Ristikivi, aasta lasteaiaõpetaja Julia Faizullova ning aasta teo tiitli pälvis Konguta kool

Uso de la distribución normal para cuantificar la calidad del riego en sistemas de aspersión estacionario

Directory of Open Access Journals (Sweden)

José Nicolás Ortiz Romero

2017-12-01

Full Text Available En el campo experimental de riego del Decanato de Agronomía de la UCLA se llevó a cabo un estudio cuyo objetivo fue cuantificar el reparto del agua y los parámetros de calidad del riego en un sistema de aspersión estacionario durante dos ciclos del cultivo de caraota usando la distribución normal. Se determinó el área adecuadamente regada (AAR en 13 eventos de riego, y esta se relacionó con los parámetros eficiencia de aplicación (Efa, pérdidas por percolación, eficiencia de almacenamiento (Efal y el déficit. Los resultados mostraron que la Efal y la percolación aumentaron con el incremento del AAR; mientras, la Efa y el déficit disminuyeron con el aumento del AAR. Los parámetros de calidad del riego en función del AAR se ajustaron apropiadamente a una regresión lineal, donde los coeficientes y el modelo resultaron significativos (p

Evolutionary Limitation and Opportunities for Developing tRNA Synthetase Inhibitors with 5-Binding-Mode Classification

Directory of Open Access Journals (Sweden)

Pengfei Fang

2015-12-01

Full Text Available Aminoacyl-tRNA synthetases (aaRSs are enzymes that catalyze the transfer of amino acids to their cognate tRNAs as building blocks for translation. Each of the aaRS families plays a pivotal role in protein biosynthesis and is indispensable for cell growth and survival. In addition, aaRSs in higher species have evolved important non-translational functions. These translational and non-translational functions of aaRS are attractive for developing antibacterial, antifungal, and antiparasitic agents and for treating other human diseases. The interplay between amino acids, tRNA, ATP, EF-Tu and non-canonical binding partners, had shaped each family with distinct pattern of key sites for regulation, with characters varying among species across the path of evolution. These sporadic variations in the aaRSs offer great opportunity to target these essential enzymes for therapy. Up to this day, growing numbers of aaRS inhibitors have been discovered and developed. Here, we summarize the latest developments and structural studies of aaRS inhibitors, and classify them with distinct binding modes into five categories.

Aminoacyl-tRNA synthetases database Y2K.

Science.gov (United States)

Szymanski, M; Barciszewski, J

2000-01-01

The aminoacyl-tRNA synthetases (AARS) are a diverse group of enzymes that ensure the fidelity of transfer of genetic information from DNA into protein. They catalyse the attachment of amino acids to transfer RNAs and thereby establish the rules of the genetic code by virtue of matching the nucleotide triplet of the anticodon with its cognate amino acid. Currently, 818 AARS primary structures have been reported from archaebacteria, eubacteria, mitochondria, chloro-plasts and eukaryotic cells. The database is a compilation of the amino acid sequences of all AARSs, known to date, which are available as separate entries or alignments of related proteins via the WWW at http://rose.man.poznan.pl/aars/index.html

75 FR 59108 - Positive Train Control Systems

Science.gov (United States)

2010-09-27

..., place the two agencies in conflict. According to AAR, ``[i]f under the PHMSA analysis of two routes one... requirement conflicts with RSIA08. AAR states that: [i]f FRA decides that TIH should be routed on a line... an inevitable impact on some routing decisions. One of the 27 factors called out for analysis under...

76 FR 52918 - Positive Train Control Systems

Science.gov (United States)

2011-08-24

... Railroads (AAR) filed suit in the U.S. Court of Appeals for the District of Columbia Circuit challenging the..., 2010, the AAR filed a petition for review of the rule with the U.S. Court of Appeals for the District... rational bases. IV. Regulatory Impact and Notices A. Executive Orders 12866 and 13563 and DOT Regulatory...

Interesting coin finds of 2006 / Mauri Kiudsoo

Index Scriptorium Estoniae

Kiudsoo, Mauri, 1973-

2007-01-01

2006. aasta huvitavamatest mündileidudest. Lisaks arheoloogilistelt kaevamistelt saadud vermingutele omandati 2006. aastal kolm mündiaaret : Alansi aare Harjumaalt, ligi poolsada araabia hõbemünti sisaldav aare Tartust ning tänu politsei kaasabile jõudsid Eestisse tagasi Ubina hõbeaadre kaevamistelt varastatud hõbemündid. Eestist leitud rooma müntidest

Rein Maran soovitab / Rein Maran

Index Scriptorium Estoniae

Maran, Rein, 1931-

2007-01-01

Silmas pidades 19. septembril avatavat 5. Matsalu rahvusvahelist loodusfilmide festivali kirjutab autor loodusfilmi rollist ja olemusest ning tutvustab Gay ja Anita Chaumette'i filmi "Räägime kaladega" ("Talking with Fishes") : Suurbritannia 2003

Heie Treier soovitab / Heie Treier

Index Scriptorium Estoniae

Treier, Heie, 1963-

2000-01-01

Ülevaade teatrikunstniku Vladimir Anshoni loomingu paremikust, mis on sündinud koostöös eesti teatritega, Kunstihoone galeriis. Helsingis kultuuripealinna "Helsinki 2000" ürituste raames fotonäitused: Robert Capa fotod Helsingi Linna Kunstimuuseumis, Tennisepalees 28. märtsini; Henri Cartier-Bressoni näitus "Eurooplased" Helsingi Linna Kunstimuuseumis 30. aprillini. H. Cartier-Bresson on pildistanud ka Tallinna "sürreaalsust".

Eesti e-varamu esimesest etapist / Malle Ermel

Index Scriptorium Estoniae

Ermel, Malle, 1949-

2016-01-01

Projekti käigus ehitati ja sisustati ka TLÜ Akadeemilise Raamatukogu digiteerimiskeskuse ruumid. E-varamu portaali ja Tallinna Ülikooli Akadeemilise Raamatukogu e-teadusraamatukogu ETERA kaudu on kasutajatele kättesaadavad ka TLÜ AR-i digikogud

Asjadeküllane Decorate Life / Aili Ermel

Index Scriptorium Estoniae

Ermel, Aili

2008-01-01

Frankfurdis juulis toimunud tarbekaupade messist "Decorate Life". Noorte disainerite Kotaro Nishibori ja Sebastian Herkneri valgustid ning René Mülleri täispuidust tooted (firma Woodloops) tuppa ja terrassile

Fosforiidisõda / Juhan Aare

Index Scriptorium Estoniae

Aare, Juhan, 1948-

1999-01-01

Järg Jan/5;6;7;8;9;11;12;13;14;15;16;18;19;20;21;22;23;25;26;27;28;29;30/Feb/1;2;3;4;5;6;8;9;10;11;12;13;15;16;17;18;19;20;22;23;25;26;27/Mar/1;2;3;4;5;6;8;9;10;11;12;13;15;16;17;18;20;22;23;24;25;26;27;29;30;31/Apr/1;2;35;6;7;8;9;10;12;13;14;15;16;17;19;20;21;22;23;24;26;27;28;29;30/May/3;4;5;6;7;8;10;11;12;13;14;15;17;18;19;20;21;22;24;25;26;27;28;29;31

Current Practice and Theoretical Foundations of the After Action Review

Science.gov (United States)

2011-06-01

Stephen L. Goldberg , Chief U.S. Army Research Institute for the Behavioral and Social Sciences 2511 Jefferson Davis Highway, Arlington, Virginia...were many occasions where 37 the facilitators’ knowledge of the battle tempo , dynamics, and resources added to the SA of team members. Such...attending AARs. There appear to be frequent variations in organizational status among participants in traditional industry AARs. In military

Puhu ristist maailma teedele / Helmut Piirimäe

Index Scriptorium Estoniae

Piirimäe, Helmut, 1930-

2009-01-01

Tutvustus: Varje dag...-sextio år av lycka. Till minnet av Aare R. Mörner (1926-2008). Utgivare: Magnus och Henrik Mörner. Printed in Hungary, 2008. /Tõlge/: Iga päev...- kuuskümmend aastat õnne. Aare-R. Mörneri (1926-2008) mälestuseks. Väljaandjad: Magnus ja Henrik Mörner. Trükitud Ungaris, 2008. 199 lk.

The growing pipeline of natural aminoacyl-tRNA synthetase inhibitors for malaria treatment.

Science.gov (United States)

Saint-Léger, Adélaïde; Sinadinos, Christopher; Ribas de Pouplana, Lluís

2016-04-02

Malaria remains a major global health problem. Parasite resistance to existing drugs makes development of new antimalarials an urgency. The protein synthesis machinery is an excellent target for the development of new anti-infectives, and aminoacyl-tRNA synthetases (aaRS) have been validated as antimalarial drug targets. However, avoiding the emergence of drug resistance and improving selectivity to target aaRS in apicomplexan parasites, such as Plasmodium falciparum, remain crucial challenges. Here we discuss such issues using examples of known inhibitors of P. falciparum aaRS, namely halofuginone, cladosporin and borrelidin (inhibitors of ProRS, LysRS and ThrRS, respectively). Encouraging recent results provide useful guidelines to facilitate the development of novel drug candidates which are more potent and selective against these essential enzymes.

Päästeametile tänu ja kurbusega / Mihhail Lotman

Index Scriptorium Estoniae

Lotman, Mihhail, 1952-

2008-01-01

President Toomas Hendrik Ilves jättis välja kuulutamata Riigikogus heaks kiidetud Riigikogu liikme palga ajutise korralduse seaduse, kuna see on vastuolus põhiseadusega. Endine Riigikogu liige, semiootikaprofessor soovitab presidendil meelde tuletada prantsuse valgustajast filosoofi Charles de Montesquieu põhiteost "Seaduste vaim" ja oma edaspidises tegevuses rohkem juhinduda seaduste vaimust, aga mitte ortograafiast. Artikli autori tänusõnad päästetöötajatele, kes on pühendunud teiste inimeste päästmisele, kuid on ise majanduslikult abitud

The alpha(2a)-adrenergic receptor plays a protective role in mouse behavioral models of depression and anxiety.

Science.gov (United States)

Schramm, N L; McDonald, M P; Limbird, L E

2001-07-01

The noradrenergic system is involved in the regulation of many physiological and psychological processes, including the modulation of mood. The alpha(2)-adrenergic receptors (alpha(2)-ARs) modulate norepinephrine release, as well as the release of serotonin and other neurotransmitters, and are therefore potential targets for antidepressant and anxiolytic drug development. The current studies were undertaken to examine the role of the alpha(2A) subtype of alpha(2)-AR in mouse behavioral models of depression and anxiety. We have observed that the genetic knock-out of the alpha(2A)-AR makes mice less active in a modified version of Porsolt's forced swim test and insensitive to the antidepressant effects of the tricyclic drug imipramine in this paradigm. Furthermore, alpha(2A)-AR knock-out mice appear more anxious than wild-type C57 Bl/6 mice in the rearing and light-dark models of anxiety after injection stress. These findings suggest that the alpha(2A)-AR may play a protective role in some forms of depression and anxiety and that the antidepressant effects of imipramine may be mediated by the alpha(2A)-AR.

A randomized controlled trial with a Canadian electronic pill dispenser used to measure and improve medication adherence in patients with schizophrenia.

Science.gov (United States)

Stip, Emmanuel; Vincent, Philippe D; Sablier, Juliette; Guevremont, Catherine; Zhornitsky, Simon; Tranulis, Constantin

2013-01-01

Medication adherence is extremely important in preventing relapse and lowering symptoms in schizophrenic patients. However, estimates show that nearly half of these patients have poor adherence. The Brief Adherence Rating Scale (BARS) seems to be the most reliable tool assessing adherence in schizophrenia and shows that the antipsychotic adherence ratio (AAR) is about 49.5% in schizophrenia. The aim of the study was to test if an electronic pill dispenser named DoPill(®) improved AAR of schizophrenic patients. Furthermore, we compared AAR obtained by the DoPill(®) and the BARS, in order to verify whether the DoPill(®) provides reliable assessment of medication adherence. The DoPill(®) is a smart pill dispenser that beeps and flashes at the appropriate time of the day. Each of its 28 compartments is covered by a plastic lamina that, when taken off, sends a signal to the pharmacist. Patients were randomized to the DoPill(®) or treatment as usual groups for 6 weeks. The BARS was used as a reference measure. Forty-six percent of patients were deemed to be non-adherent with antipsychotic medication. The mean AAR was 67% after 6 weeks. DoPill(®) recorded better AAR than some of those found in the literature and were lower than the BARS estimate we found. These results suggest that DoPill(®) is a valid tool that provides more reliable and objective data for the clinician about their patient's adherence, than existing assessment tools like the BARS. Furthermore, the device may help patients successfully manage their medication regimen.

New erection program of the hydroelectric power plant Beznau. Das Neubauprojekt des hydraulischen Kraftwerkes Beznau

Energy Technology Data Exchange (ETDEWEB)

Bretscher, B; Hauenstein, W [NOK Nordostschweizerische Kraftwerke AG, Baden (Switzerland)

1992-02-21

The projected hydroelectric power plant at Beznau on the Aare river will produce about 43% more electric power than the present hydroelectric power plant. The water level and the buildings in the Aare will remain unchanged, so that the enviromental impact will be relativley slight. The project is in accordance with the building permit so that no adaptations on modifications will be required. (orig.).

Analysis of Feedback in after Action Reviews

Science.gov (United States)

1987-06-01

CONNTSM Page INTRODUCTIUN . . . . . . . . . . . . . . . . . . . A Perspective on Feedback. . ....... • • ..... • 1 Overviev of %,•urrent Research...part of their training program . The AAR is in marked contrast to the critique method of feedback which is often used in military training. The AAR...feedback is task-inherent feedback. Task-inherent feedback refers to human-machine interacting systems, e.g., computers , where in a visual tracking task

Electric potential structures of auroral acceleration region border from multi-spacecraft Cluster data

Science.gov (United States)

Sadeghi, S.; Emami, M. R.

2018-04-01

This paper studies an auroral event using data from three spacecraft of the Cluster mission, one inside and two at the poleward edge of the bottom of the Auroral Acceleration Region (AAR). The study reveals the three-dimensional profile of the region's poleward boundary, showing spatial segmentation of the electric potential structures and their decay in time. It also depicts localized magnetic field variations and field-aligned currents that appear to have remained stable for at least 80 s. Such observations became possible due to the fortuitous motion of the three spacecraft nearly parallel to each other and tangential to the AAR edge, so that the differences and variations can be seen when the spacecraft enter and exit the segmentations, hence revealing their position with respect to the AAR.

A randomized-controlled trial with a Canadian electronic pill dispenser used to measure and improve medication adherence in patients with schizophrenia

Directory of Open Access Journals (Sweden)

Emmanuel eStip

2013-08-01

Full Text Available Objective: Medication adherence is extremely important in preventing relapse and lowering symptoms in schizophrenic patients. However, estimates show that nearly half of these patients have poor adherence. The Brief Adherence Rating Scale (BARS seems to be the most reliable tool assessing adherence in schizophrenia and shows that the antipsychotic adherence ratio (AAR is about 49.5 % in schizophrenia. The aim of the study was to test if an electronic pill dispenser named DoPill® improved AAR of schizophrenic patients. Furthermore, we compared AAR obtained by the DoPill® and the BARS, in order to verify whether the DoPill® provides reliable assessment of medication adherence. Methods: The DoPill® is a smart pill dispenser that beeps and flashes at the appropriate time of the day. Each of its 28 compartments is covered by a plastic lamina that, when taken off, sends a signal to the pharmacist. Patients were randomized to the DoPill® or Treatment As Usual group (TAU for six weeks. The BARS was used as a reference measure. Results: Forty-six percent of patients were deemed to be non-adherent with antipsychotic medication. The mean AAR was 67 % after six weeks. DoPill® recorded better AAR than some of those found in the literature and were lower than the BARS estimate we found. Conclusion: These results suggest that DoPill® is a valid tool that provides more reliable and objective data for the clinician about their patient’s adherence, than existing assessment tools like the BARS. Furthermore, the device may help patients successfully manage their medication regimen.

Area at risk can be assessed by iodine-123-meta-iodobenzylguanidine single-photon emission computed tomography after myocardial infarction: a prospective study.

Science.gov (United States)

Hedon, Christophe; Huet, Fabien; Ben Bouallegue, Fayçal; Vernhet, Hélène; Macia, Jean-Christophe; Cung, Thien-Tri; Leclercq, Florence; Cade, Stéphane; Cransac, Frédéric; Lattuca, Benoit; Vandenberghe, D'Arcy; Bourdon, Aurélie; Benkiran, Meriem; Vauchot, Fabien; Gervasoni, Richard; D'estanque, Emmanuel; Mariano-Goulart, Denis; Roubille, François

2018-02-01

Myocardial salvage is an important surrogate endpoint to estimate the impact of treatments in patients with ST-segment elevation myocardial infarction (STEMI). The aim of this study was to evaluate the correlation between cardiac sympathetic denervation area assessed by single-photon emission computed tomography (SPECT) using iodine-123-meta-iodobenzylguanidine (I-MIBG) and myocardial area at risk (AAR) assessed by cardiac magnetic resonance (CMR) (gold standard). A total of 35 postprimary reperfusion STEMI patients were enrolled prospectively to undergo SPECT using I-MIBG (evaluates cardiac sympathetic denervation) and thallium-201 (evaluates myocardial necrosis), and to undergo CMR imaging using T2-weighted spin-echo turbo inversion recovery for AAR and postgadolinium T1-weighted phase sensitive inversion recovery for scar assessment. I-MIBG imaging showed a wider denervated area (51.1±16.0% of left ventricular area) in comparison with the necrosis area on thallium-201 imaging (16.1±14.4% of left ventricular area, Parea (P=0.23) and was adequately correlated (R=0.56, P=0.0002). Myocardial salvage evaluated by SPECT imaging (mismatch denervated but viable myocardium) was significantly higher than by CMR (P=0.02). In patients with STEMI, I-MIBG SPECT, assessing cardiac sympathetic denervation may precisely evaluate the AAR, providing an alternative to CMR for AAR assessment.

The effect of alkali-aggregate reaction on concrete bridge structures

Directory of Open Access Journals (Sweden)

Grković Slobodan

2016-01-01

Full Text Available This paper shows contemporary issues related to unfavorable effects of concrete alkali-aggregate reaction (AAR on concrete bridge structures (CBS. Although AAR unfavorable effects on CBS were identified in 1930s, it was much later that AAR was acknowledged as one of the most pronounced deterioration processes in concrete that results in damages to concrete structures. There are two basic forms of AAR: alkali-silica reaction (ASR and alkali-carbonate reaction (ACR. Compared to ACR, ASR is more prominent, especially in certain geographic parts of the world. Damages to concrete caused by the ASR have negative effect primarily on usability and durability of CBS, what is followed by the decrease in load bearing capacity of structural components and reliability of the whole structure, shortening of service life (SL and costly repairs. For CBS, simultaneous occurrence of ASR and other degradation processes in concrete, such as those caused by the presence of moisture, water, temperature variations and use of deicing salt during winter, are especially damaging. Based on review of the most relevant literature, this paper is focused on mechanisms and mechanisms factors of the ASR, related contemporary research and reliability design guidelines for CBS that are based on prevention of the initiation and development of ASR.

Quantification of myocardial area at risk in the absence of collateral flow: the validation of angiographic scores by myocardial perfusion single-photon emission computed tomography.

Science.gov (United States)

Rodríguez-Palomares, José F; Alonso, Albert; Martí, Gerard; Aguadé-Bruix, Santiago; González-Alujas, M T; Romero-Farina, Guillermo; Candell-Riera, Jaume; García del Blanco, Bruno; Evangelista, Artur; García-Dorado, David

2013-02-01

Our study aimed to compare the area at risk (AAR) determined by single-photon emission computed tomography (SPECT) with the Bypass Angioplasty Revascularization Investigation (BARI) and modified Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) angiographic scores in the setting of patients undergoing coronary angioplasty for either unstable angina or an STEMI. Radionuclide myocardial perfusion imaging prior to reperfusion has classically been the most widely practised technique for assessing the AAR and has been successfully used to compare the efficacy of various reperfusion strategies in patients with an ST-segment elevation myocardial infarction (STEMI). The BARI and modified APPROACH scores are angiographic methods widely used to provide a rapid estimation of the AAR; however, they have not been directly validated with myocardial perfusion single-photon emission computed tomography (SPECT). Fifty-five patients with no previous myocardial infarction who underwent coronary angioplasty for single-vessel disease (unstable angina: n = 25 or an STEMI: n = 30) with no evidence of collaterals (Rentrop Collateral Score collateral flow, BARI and APPROACH scores constitute valid methods for AAR estimation in current clinical practice, with more accurate results when used for the LAD territory; both are useful not only in STEMI patients but also in patients with unstable angina.

Urban Combat Advanced Training Technology (Technologie avancee d’entrainement au combat urbain)

Science.gov (United States)

2015-07-01

For example, skills and drills (techniques) in an urban environment can be best trained or evaluated in a live environment, because other simulations...evidence as an AAR, and have the required skills to conduct an effective AAR. Some key 0 /C tasks are listed below. The precise tasks will be dependent...improvised “ Helpers ”, breaching material. Demo-Buildings and Showcases Detail of cut-away buildings, set-piece demonstrations and prepared rooms. STO

Loengud seaduseelnõude koostajaile / Margit Kikas

Index Scriptorium Estoniae

Kikas, Margit

2004-01-01

Eesti Juristide Liidu poolt koostöös Riigikantselei ja Justiitsministeeriumiga korraldatud loengusarjast: Õigusloome ja normitehnika: areng ja probleemid. Sõnavõtjad loengutel: Raul Narits, Katre Kont-Kontson, Lauri Mälksoo, Raigo Sõlg, Jüri Heinla, Anno Aedmaa, Aare Kasemets, Juhani Lemmik, Ülo Siivelt, Külli Koit, Aare Reenumägi, Mall Gramberg, Toomas Sepp, Julia Laffranque, Kristel Aguraiuja, Aime Vettik, Hille Saluäär, Hiie Tamm, Kristina Nõgols, Eve Randvere

The growing pipeline of natural aminoacyl-tRNA synthetase inhibitors for malaria treatment

OpenAIRE

Saint-L?ger, Ad?la?de; Sinadinos, Christopher; Ribas de Pouplana, Llu?s

2016-01-01

Malaria remains a major global health problem. Parasite resistance to existing drugs makes development of new antimalarials an urgency. The protein synthesis machinery is an excellent target for the development of new anti-infectives, and aminoacyl-tRNA synthetases (aaRS) have been validated as antimalarial drug targets. However, avoiding the emergence of drug resistance and improving selectivity to target aaRS in apicomplexan parasites, such as Plasmodium falciparum, remain crucial challenge...

Attenuation of alpha2A-adrenergic receptor expression in neonatal rat brain by RNA interference or antisense oligonucleotide reduced anxiety in adulthood.

Science.gov (United States)

Shishkina, G T; Kalinina, T S; Dygalo, N N

2004-01-01

Brain alpha2-adrenergic receptors (alpha2-ARs) have been implicated in the regulation of anxiety, which is associated with stress. Environmental treatments during neonatal development could modulate the level of brain alpha2-AR expression and alter anxiety in adults, suggesting possible involvement of these receptors in early-life programming of anxiety state. The present study was undertaken to determine whether the reduction of the expression of A subtype of these receptors most abundant in the neonatal brain affects anxiety-related behavior in adulthood. We attenuated the expression of alpha2A-ARs during neonatal life by two different sequence specific approaches, antisense technology and RNA interference. Treatment of rats with the antisense oligodeoxynucleotide or short interfering RNA (siRNA) against alpha2A-ARs on the days 2-4 of their life, produced a marked acute decrease in the levels of both alpha2A-AR mRNA and [3H]RX821002 binding sites in the brainstem into which drugs were injected. The decrease of alpha2A-AR expression in the neonatal brainstem influenced the development of this receptor system in the brain regions as evidenced by the increased number of [3H]RX821002 binding sites in the hypothalamus of adult animals with both neonatal alpha2A-AR knockdown treatments; also in the frontal cortex of antisense-treated, and in the hippocampus of siRNA-treated adult rats. These adult animals also demonstrated a decreased anxiety in the elevated plus-maze as evidenced by an increased number of the open arm entries, greater proportion of time spent in the open arms, and more than a two-fold increase in the number of exploratory head dips. The results provide the first evidence that the reduction in the brain expression of a gene encoding for alpha2A-AR during neonatal life led to the long-term neurochemical and behavioral alterations. The data suggests that alterations in the expression of the receptor-specific gene during critical periods of brain

A randomized controlled trial with a Canadian electronic pill dispenser used to measure and improve medication adherence in patients with schizophrenia

OpenAIRE

Stip, Emmanuel; Vincent, Philippe D.; Sablier, Juliette; Guevremont, Catherine; Zhornitsky, Simon; Tranulis, Constantin

2013-01-01

Objective: Medication adherence is extremely important in preventing relapse and lowering symptoms in schizophrenic patients. However, estimates show that nearly half of these patients have poor adherence. The Brief Adherence Rating Scale (BARS) seems to be the most reliable tool assessing adherence in schizophrenia and shows that the antipsychotic adherence ratio (AAR) is about 49.5% in schizophrenia. The aim of the study was to test if an electronic pill dispenser named DoPill® improved AAR...

α(2A)-adrenergic receptors filter parabrachial inputs to the bed nucleus of the stria terminalis.

Science.gov (United States)

Flavin, Stephanie A; Matthews, Robert T; Wang, Qin; Muly, E Chris; Winder, Danny G

2014-07-09

α2-adrenergic receptors (AR) within the bed nucleus of the stria terminalis (BNST) reduce stress-reward interactions in rodent models. In addition to their roles as autoreceptors, BNST α(2A)-ARs suppress glutamatergic transmission. One prominent glutamatergic input to the BNST originates from the parabrachial nucleus (PBN) and consists of asymmetric axosomatic synapses containing calcitonin gene-related peptide (CGRP) and vGluT2. Here we provide immunoelectron microscopic data showing that many asymmetric axosomatic synapses in the BNST contain α(2A)-ARs. Further, we examined optically evoked glutamate release ex vivo in BNST from mice with virally delivered channelrhodopsin2 (ChR2) expression in PBN. In BNST from these animals, ChR2 partially colocalized with CGRP, and activation generated EPSCs in dorsal anterolateral BNST neurons that elicited two cell-type-specific outcomes: (1) feedforward inhibition or (2) an EPSP that elicited firing. We found that the α(2A)-AR agonist guanfacine selectively inhibited this PBN input to the BNST, preferentially reducing the excitatory response in ex vivo mouse brain slices. To begin to assess the overall impact of α(2A)-AR control of this PBN input on BNST excitatory transmission, we used a Thy1-COP4 mouse line with little postsynaptic ChR2 expression nor colocalization of ChR2 with CGRP in the BNST. In slices from these mice, we found that guanfacine enhanced, rather than suppressed, optogenetically initiated excitatory drive in BNST. Thus, our study reveals distinct actions of PBN afferents within the BNST and suggests that α(2A)-AR agonists may filter excitatory transmission in the BNST by inhibiting a component of the PBN input while enhancing the actions of other inputs. Copyright © 2014 the authors 0270-6474/14/349319-13$15.00/0.

Automatic localization of IASLC-defined mediastinal lymph node stations on CT images using fuzzy models

Science.gov (United States)

Matsumoto, Monica M. S.; Beig, Niha G.; Udupa, Jayaram K.; Archer, Steven; Torigian, Drew A.

2014-03-01

Lung cancer is associated with the highest cancer mortality rates among men and women in the United States. The accurate and precise identification of the lymph node stations on computed tomography (CT) images is important for staging disease and potentially for prognosticating outcome in patients with lung cancer, as well as for pretreatment planning and response assessment purposes. To facilitate a standard means of referring to lymph nodes, the International Association for the Study of Lung Cancer (IASLC) has recently proposed a definition of the different lymph node stations and zones in the thorax. However, nodal station identification is typically performed manually by visual assessment in clinical radiology. This approach leaves room for error due to the subjective and potentially ambiguous nature of visual interpretation, and is labor intensive. We present a method of automatically recognizing the mediastinal IASLC-defined lymph node stations by modifying a hierarchical fuzzy modeling approach previously developed for body-wide automatic anatomy recognition (AAR) in medical imagery. Our AAR-lymph node (AAR-LN) system follows the AAR methodology and consists of two steps. In the first step, the various lymph node stations are manually delineated on a set of CT images following the IASLC definitions. These delineations are then used to build a fuzzy hierarchical model of the nodal stations which are considered as 3D objects. In the second step, the stations are automatically located on any given CT image of the thorax by using the hierarchical fuzzy model and object recognition algorithms. Based on 23 data sets used for model building, 22 independent data sets for testing, and 10 lymph node stations, a mean localization accuracy of within 1-6 voxels has been achieved by the AAR-LN system.

Siim Nestor soovitab : Zahir / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2007-01-01

Ansambli Zahir debüütalbumi "Green Means Go" esitluskontserdist 8. märtsil Tallinnas Von Krahlis (kaasa teeb ans. Andur). Ameerika diskor ja produtsent DJ Karizma 9. veebr. Tallinna klubis Privé üritusel "Defected in the House"

Siim Nestor soovitab : Eclectica / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2005-01-01

Nu-weird-folk tähe Kago albumiesitlus 2. sept. Lutsu teatrimajas, Tõnis Mäe ja Chalice'i ühiskontsert H. Treffneri gümnaasiumi hoovilaval, rockkontsert Toomemäel ja elektromuusikaöö "Phennophobia" Sadamateatris 2. sept., EuRoClAsH.CoM&Samizdad - elektomuusikaöö 3. sept. Sadamateatris ja Sven Grünbergi kontsert 4. sept. Peetri kirikus (kaastegev Kiwa) avangard-festivali Eclectica raames Tartus

Siim Nestor soovitab : Jõudu! / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2005-01-01

Üritustest: "HipHop Café Special" 15. dets. klubis Hollywood, "Mutant Disco" 16. dets. klubis Privé, "Turbodisko" 17. dets. Sakala keskuses Tallinnas, rockifestival Green Christmas 16. dets. Rakveres

Mari Laaniste soovitab "Persepolis" / Mari Laaniste

Index Scriptorium Estoniae

Laaniste, Mari, 1977-

2007-01-01

Lühiarvustus 11. Pimedate Ööde filmifestivali animadraamale "Persepolis" : režissöörid Marjane Satrapi (oma koomiksi järgi) ja Vincent Paronnaud : Prantsusmaa - Ameerika Ühendriigid - Iraan 2007

Raoul Kurvitz soovitab: Stalkeri monumendi etendused

Index Scriptorium Estoniae

2011-01-01

Rotermanni kvartalisse kohta, kus filmiti Andrei Tarkovski "Stalker", on kavas rajada Stalkerile pühendatud monument, mille autor on Raoul Kurvitz. Monumendi rajamise idee pärineb projekti kaasautorilt Tarvo Hanno Varreselt. 10., 11., 17., 18., 23. ja 24. septembril toimuvad monumenti tutvustavad performance'id

Automatic anatomy recognition on CT images with pathology

Science.gov (United States)

Huang, Lidong; Udupa, Jayaram K.; Tong, Yubing; Odhner, Dewey; Torigian, Drew A.

2016-03-01

Body-wide anatomy recognition on CT images with pathology becomes crucial for quantifying body-wide disease burden. This, however, is a challenging problem because various diseases result in various abnormalities of objects such as shape and intensity patterns. We previously developed an automatic anatomy recognition (AAR) system [1] whose applicability was demonstrated on near normal diagnostic CT images in different body regions on 35 organs. The aim of this paper is to investigate strategies for adapting the previous AAR system to diagnostic CT images of patients with various pathologies as a first step toward automated body-wide disease quantification. The AAR approach consists of three main steps - model building, object recognition, and object delineation. In this paper, within the broader AAR framework, we describe a new strategy for object recognition to handle abnormal images. In the model building stage an optimal threshold interval is learned from near-normal training images for each object. This threshold is optimally tuned to the pathological manifestation of the object in the test image. Recognition is performed following a hierarchical representation of the objects. Experimental results for the abdominal body region based on 50 near-normal images used for model building and 20 abnormal images used for object recognition show that object localization accuracy within 2 voxels for liver and spleen and 3 voxels for kidney can be achieved with the new strategy.

Effects of Silodosin and Tamsulosin on the Seminal Vesicle Contractile Response.

Science.gov (United States)

Hayashi, Tokumasa; Takeya, Mitsue; Nakamura, Kei-ichiro; Matsuoka, Kei

2016-01-01

To understand the mechanisms underlying ejaculation dysfunction caused by α1A-adrenocetor (AR) antagonists, the effects of α1A-AR antagonists on the contractile responses of the seminal vesicle were investigated. Isolated seminal vesicles from guinea pigs were cannulated and pressurized, and the changes in the intraluminal pressure were recorded. Periodic applications of electrical stimulation (ES) caused biphasic increase in the intraluminal pressure, that is, initial and subsequent contractions. The effects of silodosin and tamsulosin, α1A-AR antagonists, on the contractile responses were examined. The ES-induced biphasic contractions were blocked by tetrodotoxin (TTX). Silodosin and tamsulosin suppressed the initial contractions in a dose-dependent manner, while also exerting various inhibitory effects on the subsequent contractions. Increases in the intraluminal pressure facilitated spontaneous phasic contractions. The spontaneous contractions were not affected by TTX or α1A-AR antagonists, but were abolished by nifedipine. The initial contractions triggered by neuronal excitations were suppressed by silodosin and tamsulosin, suggesting that the ejaculation dysfunction may be attributed to the α1A-AR antagonist-mediated suppression of nerve-evoked contractions in the seminal vesicle. The subsequent contractions may be induced by mechanical stimulation associated with the initial, nerve-evoked contractions. Alternatively, other transmitters may be involved to various degrees in the neuromuscular transmission of the seminal vesicle. © 2014 Wiley Publishing Asia Pty Ltd.

Backbone Brackets and Arginine Tweezers delineate Class I and Class II aminoacyl tRNA synthetases

Science.gov (United States)

Haupt, V. Joachim; Schroeder, Michael; Labudde, Dirk

2018-01-01

The origin of the machinery that realizes protein biosynthesis in all organisms is still unclear. One key component of this machinery are aminoacyl tRNA synthetases (aaRS), which ligate tRNAs to amino acids while consuming ATP. Sequence analyses revealed that these enzymes can be divided into two complementary classes. Both classes differ significantly on a sequence and structural level, feature different reaction mechanisms, and occur in diverse oligomerization states. The one unifying aspect of both classes is their function of binding ATP. We identified Backbone Brackets and Arginine Tweezers as most compact ATP binding motifs characteristic for each Class. Geometric analysis shows a structural rearrangement of the Backbone Brackets upon ATP binding, indicating a general mechanism of all Class I structures. Regarding the origin of aaRS, the Rodin-Ohno hypothesis states that the peculiar nature of the two aaRS classes is the result of their primordial forms, called Protozymes, being encoded on opposite strands of the same gene. Backbone Brackets and Arginine Tweezers were traced back to the proposed Protozymes and their more efficient successors, the Urzymes. Both structural motifs can be observed as pairs of residues in contemporary structures and it seems that the time of their addition, indicated by their placement in the ancient aaRS, coincides with the evolutionary trace of Proto- and Urzymes. PMID:29659563

Validation of Contrast Enhanced Cine Steady-State Free Precession and T2-Weigthed CMR for Assessment of Ischemic Myocardial Area- At-Risk

DEFF Research Database (Denmark)

Søvsø Szocska Hansen, Esben; Pedersen, Steen Fjord; Pedersen, Steen Bønløkke

2017-01-01

-CINE) has recently been used to quantify AAR and validated against myocardial perfusion SPECT. In this study we sought to determine how well T2-STIR and CE-CINE depicts AAR in an experimental porcine model of myocardial ischemia-reperfusion injury using histopathology as the reference for infarct size......Measuring myocardial salvage is important to evaluate the possible cardioprotective effects of adjunctive cardioprotective intervention in patients with myocardial infarction undergoing primary percutaneous intervention. Contrast-enhanced steady-state free precession magnetic resonance imaging (CE...

Opportunities Missed: A Cross-Sectional Survey of the Provision of Smoking Cessation Care to Pregnant Women by Australian General Practitioners and Obstetricians.

Science.gov (United States)

Zeev, Yael Bar; Bonevski, Billie; Twyman, Laura; Watt, Kerrianne; Atkins, Lou; Palazzi, Kerrin; Oldmeadow, Christopher; Gould, Gillian S

2017-05-01

Similar to other high-income countries, smoking rates in pregnancy can be high in specific vulnerable groups in Australia. Several clinical guidelines exist, including the 5A's (Ask, Advice, Assess, Assist, and Arrange), ABCD (Ask, Brief advice, Cessation, and Discuss), and AAR (Ask, Advice, and Refer). There is lack of data on provision of smoking cessation care (SCC) of Australian General Practitioners (GPs) and Obstetricians. A cross-sectional survey explored the provision of SCC, barriers and enablers using the Theoretical Domains Framework, and the associations between them. Two samples were invited: (1) GPs and Obstetricians from a college database (n = 5571); (2) GPs from a special interest group for Indigenous health (n = 500). Dimension reduction for the Theoretical Domains Framework was achieved with factor analysis. Logistic regression was carried out for performing all the 5A's and the AAR. Performing all of the 5A's, ABCD, and AAR "often and always" was reported by 19.9%, 15.6%, and 49.2% respectively. "Internal influences" (such as confidence in counselling) were associated with higher performance of the 5A's (Adjusted OR 2.69 (95% CI 1.5, 4.8), p workplace routine) were associated with higher performance of AAR (Adjusted OR 1.7 (95% CI 1, 2.8), p = .035). Performance in providing SCC to pregnant women is low among Australian GPs and Obstetricians. Training clinicians should focus on improving internal influences such as confidence and optimism. The AAR may be easier to implement, and interventions at the service level should focus on ensuring easy, effective, and acceptable referral mechanisms are in place. Improving provision of the 5A's approach should focus on the individual level, including better training for GPs and Obstetricians, designed to improve specific "internal" barriers such as confidence in counselling and optimism. The AAR may be easier to implement in view of the higher overall performance of this approach. Interventions on a more

Insulin-increased L-arginine transport requires A(2A adenosine receptors activation in human umbilical vein endothelium.

Directory of Open Access Journals (Sweden)

Enrique Guzmán-Gutiérrez

Full Text Available Adenosine causes vasodilation of human placenta vasculature by increasing the transport of arginine via cationic amino acid transporters 1 (hCAT-1. This process involves the activation of A(2A adenosine receptors (A(2AAR in human umbilical vein endothelial cells (HUVECs. Insulin increases hCAT-1 activity and expression in HUVECs, and A(2AAR stimulation increases insulin sensitivity in subjects with insulin resistance. However, whether A(2AAR plays a role in insulin-mediated increase in L-arginine transport in HUVECs is unknown. To determine this, we first assayed the kinetics of saturable L-arginine transport (1 minute, 37°C in the absence or presence of nitrobenzylthioinosine (NBTI, 10 µmol/L, adenosine transport inhibitor and/or adenosine receptors agonist/antagonists. We also determined hCAT-1 protein and mRNA expression levels (Western blots and quantitative PCR, and SLC7A1 (for hCAT-1 reporter promoter activity. Insulin and NBTI increased the extracellular adenosine concentration, the maximal velocity for L-arginine transport without altering the apparent K(m for L-arginine transport, hCAT-1 protein and mRNA expression levels, and SLC7A1 transcriptional activity. An A2AAR antagonist ZM-241385 blocked these effects. ZM241385 inhibited SLC7A1 reporter transcriptional activity to the same extent in cells transfected with pGL3-hCAT-1(-1606 or pGL3-hCAT-1(-650 constructs in the presence of NBTI + insulin. However, SLC7A1 reporter activity was increased by NBTI only in cells transfected with pGL3-hCAT-1(-1606, and the ZM-241385 sensitive fraction of the NBTI response was similar in the absence or in the presence of insulin. Thus, insulin modulation of hCAT-1 expression and activity requires functional A(2AAR in HUVECs, a mechanism that may be applicable to diseases associated with fetal insulin resistance, such as gestational diabetes.

Effects of α2A Adrenoceptors on Norepinephrine Secretion from the Locus Coeruleus during Chronic Stress-Induced Depression

Directory of Open Access Journals (Sweden)

Hong-ping Huang

2017-05-01

Full Text Available Chronic stressors can often lead to the development of psychological disorders, such as depression and anxiety. The locus coeruleus (LC is a stress sensitive brain region located in the pons, with noradrenergic neurons that project to the hypothalamus, especially the paraventricular nucleus (PVN of the hypothalamus. The purpose of this paper is to better understand how alpha 2A-adrenoceptors (α2A-ARs and LC-hypothalamus noradrenergic system participate in the pathophysiological mechanism of depression. In vivo norepinephrine (NE release in the PVN triggered by electrical stimulation in the LC was detected with carbon fiber electrodes in depression model of rats induced by chronic unpredictable mild stress (CUMS. Also, the extracellular level of NE in the PVN was measured by microdialysis in vivo without any stimulation in the LC. The alpha 2-adrenoceptor (α2-AR antagonist yohimbine and α2A-ARs antagonist BRL-44408 maleate were systemically administered to rats to determine the effects of α2A-ARs on NE release in the PVN. The peak value of elicited NE release signals in the PVN induced by electrical stimulation in the LC in the CUMS rats were lower than that in the control rats. The extracellular levels of NE in the PVN of the CUMS rats were significantly less than that of the control rats. Intraperitoneal injection of yohimbine or BRL-44408 maleate significantly potentiated NE release in the PVN of the CUMS rats. The CUMS significantly increased protein expression levels of α2A-AR in the hypothalamus, and BRL-44408 maleate significantly reversed the increase of α2A-AR protein expression levels in the CUMS rats. Our results suggest that the CUMS could significantly facilitate the effect of α2-adrenoceptor-mediated presynaptic inhibition and decrease the release of NE in the PVN from LC. Blockade of the inhibitory action of excessive α2A-adrenergic receptors in the CUMS rats could increase the level of NE in the PVN, which is effective in

Aare Anderson : Elva-taoline väikelinn on parimaid kohti elamiseks / Aare Anderson ; interv. Mare Nõmmik

Index Scriptorium Estoniae

Anderson, Aare, 1966-

2006-01-01

Elva endine linnapea ja aselinnapea, rahandusministeeriumi töötaja vastab küsimustele, mis on seotud tema ametikohaga, Elvaga, võimalusega siduda end tulevikus poliitikaga. Isamaa ja Res Publica Liidu loosungist "Õnn ei ole rahas"

Automated Aerial Refueling Hitches a Ride on AFF

Science.gov (United States)

Hansen, Jennifer L.; Murray, James E.; Bever, Glenn; Campos, Norma V.; Schkolnik, Gerard

2007-01-01

The recent introduction of uninhabited aerial vehicles [UAVs (basically, remotely piloted or autonomous aircraft)] has spawned new developments in autonomous operation and posed new challenges. Automated aerial refueling (AAR) is a capability that will enable UAVs to travel greater distances and loiter longer over targets. NASA Dryden Flight Research Center, in cooperation with the Defense Advanced Research Projects Agency (DARPA), the Naval Air Systems Command (NAVAIR), the Naval Air Force Pacific Fleet, and the Air Force Research Laboratory, rapidly conceived and accomplished an AAR flight research project focused on collecting a unique, high-quality database on the dynamics of the hose and drogue of an aerial refueling system. This flight-derived database would be used to validate mathematical models of the dynamics in support of design and analysis of AAR systems for future UAVs. The project involved the use of two Dryden F/A-18 airplanes and an S-3 hose-drogue refueling store on loan from the Navy. In this year-long project, which was started on October 1, 2002, 583 research maneuvers were completed during 23 flights.

Anomalous rostral lumbosacral root emergence from the thecal sac

International Nuclear Information System (INIS)

Peyster, R.G.; Parghi, A.; Siegal, T.; Hershey, B.L.; Yablon, J.; Jaffe, S.

1989-01-01

Anomalous rostral lumbosacral root emergence (AARE) has important clinical implications and has received little attention. The authors have studied the occurrence of this anomaly and presentation of cases in which it was paramount in causing radiculopathy. AARE was noted with the following occurrence rates in 500 cases: L3, 0%; L4, 1%; L5, 9%, and S1, 16%. In ARRE, the roots lie laterally between the superior facet and the annulus and are subject to compression by minimal disk bulging or facet hypertrophy. One must track the individual nerve roots on lumbar CT and MR imaging to detect this subtle condition

Script Identification from Printed Indian Document Images and Performance Evaluation Using Different Classifiers

Directory of Open Access Journals (Sweden)

Sk Md Obaidullah

2014-01-01

multiscript country like India. In this paper the real life problem of printed script identification from official Indian document images is considered and performances of different well-known classifiers are evaluated. Two important evaluating parameters, namely, AAR (average accuracy rate and MBT (model building time, are computed for this performance analysis. Experiment was carried out on 459 printed document images with 5-fold cross-validation. Simple Logistic model shows highest AAR of 98.9% among all. BayesNet and Random Forest model have average accuracy rate of 96.7% and 98.2% correspondingly with lowest MBT of 0.09 s.

Accelerator assisted repositories, technical issue identification and economic assessment

Energy Technology Data Exchange (ETDEWEB)

Myers, T.; Favale, A.; Berwald, D. [Northrop Grumman Corp., Bethpage, NY (United States)

1995-12-31

An investigation (technical and economic) is presented to quantify the impact of accelerator assisted repository (AAR) system on the US national nuclear repository strategy. An overview of US spent fuel policy is presented which provides a means to comparatively assess competing spent fuel disposition technologies under investigation. The advantages of an AAR system are highlighted and discussed. A companion economic analysis is presented. The results indicate that although a US geologic waste repository will continue to be required, waste partitioning and accelerator transmutation of selected actinides, and long-lived fission products, can result in substantial benefits. (author) 18 refs.

Anneli Remme soovitab : Iisrael Egiptuses / Anneli Remme

Index Scriptorium Estoniae

Remme, Anneli, 1968-

2008-01-01

Eesti Filharmoonia Kammerkoor esitab Georg Friedrich Händeli teose "Iisrael Egiptuses" 18. dets. Vanemuise kontserdimajas, 19. dets. Estonia kontserdisaalis, 20. dets. Jõhvi kontserdimajas ja 21. dets. Pärnu kontserdimajas (dirigent Daniel Reuss)

Siim Nestor soovitab : Turbodisko. Camouflage / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2006-01-01

Üritusest "Turbodisko" 2. dets. Tallinnas KuKu klubis, indieansambli Bad Apples heliplaadi "When Colours Become Day and Night" (plaadifirmalt Seksound) esitluskontserdist. Saksamaa futuelektroonika ansambli Camouflage albumi "Relocated" esitluskontserdist 3. dets klubis Hollywood (kontserti soojendab läti ansambel STandArt)

DVD. Kaimar Palts soovitab : "Narnia" / Kaimar Palts

Index Scriptorium Estoniae

Palts, Kaimar

2006-01-01

DVD mängufilmist "Narnia lood : lõvi, nõid ja riidekapp" ("Chronicles of Narnia : The Lion, the Witch and the Wardrobe") C.S. Lewise muinasjutu ainetel : režissöör Andrew Adamson : Ameerika Ühendriigid 2005. Ka filmi lisadest DVD-l

Siim Nestor soovitab : Sola Muusika / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2005-01-01

Üritusel Sola Muusika 25. veebr. Tallinna vanalinna kohvikus Kehrwieder esinevad austraalia muusik Electroteque, shoti artist Unknown Forces ja soome muusik Good Doc, plaate mängivad Taavi Laasit, Kaarel Kattai ja Kaarel Kirikmäe

Graafika Filharmoonias : Harry Liivrand soovitab / Harry Liivrand

Index Scriptorium Estoniae

Liivrand, Harry, 1961-

2004-01-01

Alustatakse regulaarse kunstinäituse programmiga Estonia Kontserdisaalis. Avatakse graafikanäitus "Lähenemised" (koostaja Vappu Vabar). Osalevad Marje Üksine, Reti Saks, Maria-Kristiina Ulas, Kelli Kagovere, Naima Neidre jt

Saaremaa Fond turgutab õppureid / Aare Laine

Index Scriptorium Estoniae

Laine, Aare, 1951-

2012-01-01

Saaremaa Fond andis kõrgkoolides häid õpitulemusi näidanud ja pere kõrvalt õppivatele tudengitele üle aastastipendiumid. Õppiva pere stipendium: Viljandi kultuuriakadeemias rahvuslikku käsitööd õppiv Alliki Oidekivi, Tallinna ülikoolis 2. kursusel kutsepedagoogikat õppiv Ahti Paju ning Tallinna ülikoolis magistriõppes haridustehnoloogiat õppiv Irena Sink. Peeter Palu nimeline stipendium: Eesti mereakadeemia tüürimehe eriala 2. kursuse tudengile Ott Kuusele. Tallinna Sadama nimelise stipendium: mereakadeemias tüürimehe eriala õppiv Dmitri Mišin

Poeetilisest mõõtmest / Aare Pilv

Index Scriptorium Estoniae

Pilv, Aare, 1976-

2016-01-01

Luule tõlkimisest, selgitades mõistet "poeetiline mõõde". Artikli teises pooles käsitletakse ka sama keeleruumi klassikaliste luuletuste tõlkimist tänapäeva keelde, kasutades Aleksandr Puškini luuletuse "A. P. Kernile" näidet

Digitaalallkirja seadus saab sisu / Aare Reivart

Index Scriptorium Estoniae

Reivart, Aare, 1968-

2000-01-01

Sideoperaatorid ja pangad hakkavad välja töötama ühtset avalikku võtme infrastruktuuri (PKI), mis võimaldab telefoni ja interneti vahendusel kasutada mitmesuguseid teenuseid kiiresti ja turvaliselt

Poola teadlane uurib kraatrit / Aare Laine

Index Scriptorium Estoniae

Laine, Aare, 1951-

2004-01-01

Poznani ülikooli geoloogiainstituudi direktor Wojciech Stankowaki koos tudengitega võtab pinnaseproove edasiseks uurimiseks. Kahe riigi koostöö toimub mõlema riigi teaduste akadeemia ühisprogrammi "Eesti ja Poola meteoriidikraatrite võrdlev uurimine" alusel

Avariide kiuste Monte Carlosse / Aare Arula

Index Scriptorium Estoniae

Arula, Aare

2007-01-01

Vt. ka Tehnika dlja Vsehh nr. 3, lk. 26-27. 26. jaanuaril 1937 Tallinnast Monte Carlo tähesõidule startinud Karl Siitanit ja tema meeskonda ootasid ees seiklused, mis oleksid neile peaaegu elu maksnud

Silmatagusest teatrist / Sirle Põdersoo, Aare Pilv

Index Scriptorium Estoniae

Põdersoo, Sirle

2003-01-01

J. Tombergi ja Andreas W "Aurora temporalis" H. Toompere jun lavastuses Tartu Sadamateatris, Lendava Hollandlase ja Tartu Teatrilabori projekt ning "Maja Jaama uulitsas" M. Heinsaare juttude põhjal Tartu Teatrilaboris, projektijuht J. Jaanus, lavastus ja tants T. Mölder, H. Reitsnik, K. Essenson, E. Ülevain, M. Plakso, A. Vamper

Huvitavaid kohtulahendeid kindlustusasjades / Aare-Matti Inglist

Index Scriptorium Estoniae

Inglist, Aare-Matti

2007-01-01

Kindlustushüvitise määramisest tules hävinud elumaja ja koduse vara näitel (Riigikohtu lahendid 3-2-1-155-05 ja 3-21-1-155-06) ning lepinguvälise kahju hüvitamisest liiklusõnnetusjuhtumi näitel (Riigikohtu lahend 3-2-1-81-04)

Adaptive Aggregation Routing to Reduce Delay for Multi-Layer Wireless Sensor Networks.

Science.gov (United States)

Li, Xujing; Liu, Anfeng; Xie, Mande; Xiong, Neal N; Zeng, Zhiwen; Cai, Zhiping

2018-04-16

The quality of service (QoS) regarding delay, lifetime and reliability is the key to the application of wireless sensor networks (WSNs). Data aggregation is a method to effectively reduce the data transmission volume and improve the lifetime of a network. In the previous study, a common strategy required that data wait in the queue. When the length of the queue is greater than or equal to the predetermined aggregation threshold ( N t ) or the waiting time is equal to the aggregation timer ( T t ), data are forwarded at the expense of an increase in the delay. The primary contributions of the proposed Adaptive Aggregation Routing (AAR) scheme are the following: (a) the senders select the forwarding node dynamically according to the length of the data queue, which effectively reduces the delay. In the AAR scheme, the senders send data to the nodes with a long data queue. The advantages are that first, the nodes with a long data queue need a small amount of data to perform aggregation; therefore, the transmitted data can be fully utilized to make these nodes aggregate. Second, this scheme balances the aggregating and data sending load; thus, the lifetime increases. (b) An improved AAR scheme is proposed to improve the QoS. The aggregation deadline ( T t ) and the aggregation threshold ( N t ) are dynamically changed in the network. In WSNs, nodes far from the sink have residual energy because these nodes transmit less data than the other nodes. In the improved AAR scheme, the nodes far from the sink have a small value of T t and N t to reduce delay, and the nodes near the sink are set to a large value of T t and N t to reduce energy consumption. Thus, the end to end delay is reduced, a longer lifetime is achieved, and the residual energy is fully used. Simulation results demonstrate that compared with the previous scheme, the performance of the AAR scheme is improved. This scheme reduces the delay by 14.91%, improves the lifetime by 30.91%, and increases energy

Adaptive Aggregation Routing to Reduce Delay for Multi-Layer Wireless Sensor Networks

Directory of Open Access Journals (Sweden)

Xujing Li

2018-04-01

Full Text Available The quality of service (QoS regarding delay, lifetime and reliability is the key to the application of wireless sensor networks (WSNs. Data aggregation is a method to effectively reduce the data transmission volume and improve the lifetime of a network. In the previous study, a common strategy required that data wait in the queue. When the length of the queue is greater than or equal to the predetermined aggregation threshold ( N t or the waiting time is equal to the aggregation timer ( T t , data are forwarded at the expense of an increase in the delay. The primary contributions of the proposed Adaptive Aggregation Routing (AAR scheme are the following: (a the senders select the forwarding node dynamically according to the length of the data queue, which effectively reduces the delay. In the AAR scheme, the senders send data to the nodes with a long data queue. The advantages are that first, the nodes with a long data queue need a small amount of data to perform aggregation; therefore, the transmitted data can be fully utilized to make these nodes aggregate. Second, this scheme balances the aggregating and data sending load; thus, the lifetime increases. (b An improved AAR scheme is proposed to improve the QoS. The aggregation deadline ( T t and the aggregation threshold ( N t are dynamically changed in the network. In WSNs, nodes far from the sink have residual energy because these nodes transmit less data than the other nodes. In the improved AAR scheme, the nodes far from the sink have a small value of T t and N t to reduce delay, and the nodes near the sink are set to a large value of T t and N t to reduce energy consumption. Thus, the end to end delay is reduced, a longer lifetime is achieved, and the residual energy is fully used. Simulation results demonstrate that compared with the previous scheme, the performance of the AAR scheme is improved. This scheme reduces the delay by 14.91%, improves the lifetime by 30.91%, and increases

GPS navigation algorithms for Autonomous Airborne Refueling of Unmanned Air Vehicles

Science.gov (United States)

Khanafseh, Samer Mahmoud

Unmanned Air Vehicles (UAVs) have recently generated great interest because of their potential to perform hazardous missions without risking loss of life. If autonomous airborne refueling is possible for UAVs, mission range and endurance will be greatly enhanced. However, concerns about UAV-tanker proximity, dynamic mobility and safety demand that the relative navigation system meets stringent requirements on accuracy, integrity, and continuity. In response, this research focuses on developing high-performance GPS-based navigation architectures for Autonomous Airborne Refueling (AAR) of UAVs. The AAR mission is unique because of the potentially severe sky blockage introduced by the tanker. To address this issue, a high-fidelity dynamic sky blockage model was developed and experimentally validated. In addition, robust carrier phase differential GPS navigation algorithms were derived, including a new method for high-integrity reacquisition of carrier cycle ambiguities for recently-blocked satellites. In order to evaluate navigation performance, world-wide global availability and sensitivity covariance analyses were conducted. The new navigation algorithms were shown to be sufficient for turn-free scenarios, but improvement in performance was necessary to meet the difficult requirements for a general refueling mission with banked turns. Therefore, several innovative methods were pursued to enhance navigation performance. First, a new theoretical approach was developed to quantify the position-domain integrity risk in cycle ambiguity resolution problems. A mechanism to implement this method with partially-fixed cycle ambiguity vectors was derived, and it was used to define tight upper bounds on AAR navigation integrity risk. A second method, where a new algorithm for optimal fusion of measurements from multiple antennas was developed, was used to improve satellite coverage in poor visibility environments such as in AAR. Finally, methods for using data-link extracted

Salivary alpha amylase in on-call from home fire and emergency service personnel

Directory of Open Access Journals (Sweden)

Sarah J Hall

2017-10-01

Full Text Available The effect of working on-call from home on the sympatho-adrenal medullary system activity is currently unknown. This study had two aims, Aim 1: examine salivary alpha amylase awakening response (AAR and diurnal salivary alpha amylase (sAA profile in fire and emergency service workers who operate on-call from home following a night on-call with a call (NIGHT-CALL, a night on-call without a call (NO-CALL and an off-call night (OFF-CALL, and Aim 2: explore whether there was an anticipatory effect of working on-call from home (ON compared to when there was an off-call (OFF on the diurnal sAA profile. Participants wore activity monitors, completed sleep and work diaries and collected seven saliva samples a day for one week. AAR area under the curve with respect to ground (AUCG, AAR area under the curve with respect to increase (AUCI, AAR reactivity, diurnal sAA slope, diurnal sAA AUCG and mean 12-h sAA concentrations were calculated. Separate generalised estimating equation models were constructed for each variable of interest for each aim. For Aim 1, there were no differences between NIGHT-CALL or NO-CALL and OFF-CALL for any response variable. For Aim 2, there was no difference between any response variable of interest when ON the following night compared to when OFF the following night (n = 14. These findings suggest that there is no effect of working on-call from home on sAA, but should be interpreted with caution, as overnight data were not collected. Future research, using overnight heart rate monitoring, could help confirm these findings.

Alpha1a-Adrenoceptor Genetic Variant Triggers Vascular Smooth Muscle Cell Hyperproliferation and Agonist Induced Hypertrophy via EGFR Transactivation Pathway.

Directory of Open Access Journals (Sweden)

Irina Gradinaru

Full Text Available α1a Adrenergic receptors (α1aARs are the predominant AR subtype in human vascular smooth muscle cells (SMCs. α1aARs in resistance vessels are crucial in the control of blood pressure, yet the impact of naturally occurring human α1aAR genetic variants in cardiovascular disorders remains poorly understood. To this end, we present novel findings demonstrating that 3D cultures of vascular SMCs expressing human α1aAR-247R (247R genetic variant demonstrate significantly increased SMC contractility compared with cells expressing the α1aAR-WT (WT receptor. Stable expression of 247R genetic variant also triggers MMP/EGFR-transactivation dependent serum- and agonist-independent (constitutive hyperproliferation and agonist-dependent hypertrophy of SMCs. Agonist stimulation reduces contractility Using pathway-specific inhibitors we determined that the observed hyperproliferation of 247R-expressing cells is triggered via β-arrestin1/Src/MMP-2/EGFR/ERK-dependent mechanism. MMP-2-specific siRNA inhibited 247R-triggered hyperproliferation indicating MMP-2 involvement in 247R-triggered hyperproliferation in SMCs. β-arrestin1-specific shRNA also inhibited 247R-triggered hyperproliferation but did not affect hypertrophy in 247R-expressing SMCs, indicating that agonist-dependent hypertrophy is independent of β-arrestin1. Our data reveal that in different cardiovascular cells the same human receptor genetic variant can activate alternative modulators of the same signaling pathway. Thus, our findings in SMCs demonstrate that depending on the type of cells expressing the same receptor (or receptor variant, different target-specific inhibitors could be used to modulate aberrant hyperproliferative or hypertrophic pathways in order to restore normal phenotype.

USA suursaadik : Eesti peaks meedia tähelepanu ära kasutama / Stanley Davis Phillips ; interv. Holger Roonemaa

Index Scriptorium Estoniae

Phillips, Stanley Davis

2007-01-01

USA suursaadik räägib Tõnismäe pronkssõdurist, viisavabaduse võimalikkusest Eesti ja USA vahel, suursaadiku plaanidest Eestis, president Toomas Hendrik Ilvese eelseisvast kohtumisest USA presidendi George W. Bushiga, USA ja Venemaa suhetest, Iraagi sõjast ning kommenteerib ühe USA presidendikandidaadi Pat Buchanani väidet, et USA jaoks oleks absurdne astuda sõtta näiteks Venemaaga, et kaitsta Eestit. Suursaadik soovitab Eestil aktiivselt ära kasutada Venemaa-poolsete küberrünnakutega kaasnenud meediakajastust. Ilmunud ka: Vaba Eesti Sõna 7. juuni 2007, lk. 10; ingl. k. Eesti Elu 8. juuni 2007, lk. 8-9, pealk.: U.S Ambassador: Estonia should take advantage of media attention

Alanyl-tRNA synthetase mutation in a family with dominant distal hereditary motor neuropathy

Science.gov (United States)

Zhao, Z.; Hashiguchi, A.; Sakiyama, Y.; Okamoto, Y.; Tokunaga, S.; Zhu, L.; Shen, H.; Takashima, H.

2012-01-01

Objective: To identify a new genetic cause of distal hereditary motor neuropathy (dHMN), which is also known as a variant of Charcot-Marie-Tooth disease (CMT), in a Chinese family. Methods: We investigated a Chinese family with dHMN clinically, electrophysiologically, and genetically. We screened for the mutations of 28 CMT or related pathogenic genes using an originally designed microarray resequencing DNA chip. Results: Investigation of the family history revealed an autosomal dominant transmission pattern. The clinical features of the family included mild weakness and wasting of the distal muscles of the lower limb and foot deformity, without clinical sensory involvement. Electrophysiologic studies revealed motor neuropathy. MRI of the lower limbs showed accentuated fatty infiltration of the gastrocnemius and vastus lateralis muscles. All 4 affected family members had a heterozygous missense mutation c.2677G>A (p.D893N) of alanyl-tRNA synthetase (AARS), which was not found in the 4 unaffected members and control subjects. Conclusion: An AARS mutation caused dHMN in a Chinese family. AARS mutations result in not only a CMT phenotype but also a dHMN phenotype. PMID:22573628

Integrated Battlefield Effects Research for the National Training Center. Appendix E. Requirements Design Specification and Demonstration Report for the Exercise Coordination and Control (ECC) Demonstration System

Science.gov (United States)

1984-12-31

mode 3. Edit AAR mode 4. Run AR mode Each of the modes shall be mutually eclusive. In the real-time mode, the station tactical display shall reflect...periods of the exercise segment. The edit AAR mode shall provide the operator with the capability of creating/ editing a command file for use during an...II .,II IH 0 - hUi I -24 .6d, -I" @ 0 M% A A a a dJ a) 6 I I - -- a’ 1.* % 46- 8 ’ 0 "S 8 -- -- "- - I .-36 aISa "S-a:z:-a I I b 0 Il -- I -- I1 -I

An inexpensive underwater mine countermeasures simulator with real-time 3D after action review

Directory of Open Access Journals (Sweden)

Robert Stone

2016-10-01

Full Text Available This paper presents the results of a concept capability demonstration pilot study, the aim of which was to investigate how inexpensive gaming software and hardware technologies could be exploited in the development and evaluation of a simulator prototype for training Royal Navy mine clearance divers, specifically focusing on the detection and accurate reporting of the location and condition of underwater ordnance. The simulator was constructed using the Blender open source 3D modelling toolkit and game engine, and featured not only an interactive 3D editor for underwater scenario generation by instructors, but also a real-time, 3D After Action Review (AAR system for formative assessment and feedback. The simulated scenarios and AAR architecture were based on early human factors observations and briefings conducted at the UK's Defence Diving School (DDS, an organisation that provides basic military diving training for all Royal Navy and Army (Royal Engineers divers. An experimental pilot study was undertaken to determine whether or not basic navigational and mine detection components of diver performance could be improved as a result of exposing participants to the AAR system, delivered between simulated diving scenarios. The results suggest that the provision of AAR was accompanied by significant performance improvements in the positive identification of simulated underwater ordnance (in contrast to non-ordnance objects and on participants' description of their location, their immediate in-water or seabed context and their structural condition. Only marginal improvements were found with participants' navigational performance in terms of their deviation accuracies from a pre-programmed expert search path. Overall, this project contributes to the growing corpus of evidence supporting the development of simulators that demonstrate the value of exploiting open source gaming software and the significance of adopting established games design

Alkane biosynthesis genes in cyanobacteria and their transcriptional organization

Directory of Open Access Journals (Sweden)

Stephan eKlähn

2014-07-01

Full Text Available In cyanobacteria, alkanes are synthesized from a fatty acyl-ACP by two enzymes, acyl-acyl carrier protein reductase (AAR and aldehyde deformylating oxygenase (ADO. Despite the great interest in the exploitation for biofuel production, nothing is known about the transcriptional organization of their genes or the physiological function of alkane synthesis. The comparison of 115 microarray datasets indicates the relatively constitutive expression of aar and ado genes. The analysis of 181 available genomes showed that in 90% of the genomes both genes are present, likely indicating their physiological relevance. In 61% of them they cluster together with genes encoding acetyl-CoA carboxyl transferase and a short chain dehydrogenase, strengthening the link to fatty acid metabolism and in 76% of the genomes they are located in tandem, suggesting constraints on the gene arrangement. However, contrary to the expectations for an operon, we found in Synechocystis sp. PCC 6803 specific promoters for the two genes, sll0208 (ado and sll0209 (aar, that give rise to monocistronic transcripts. Moreover, the upstream located ado gene is driven by a proximal as well as a second, distal, promoter, from which a third transcript, the ~160 nt sRNA SyR9 is transcribed. Thus, the transcriptional organization of the alkane biosynthesis genes in Synechocystis sp. PCC 6803 is of substantial complexity. We verified all three promoters to function independently from each other and show a similar promoter arrangement also in the more distant Nodularia spumigena, Trichodesmium erythraeum, Anabaena sp. PCC 7120, Prochlorococcus MIT9313 and MED4. The presence of separate regulatory elements and the dominance of monocistronic mRNAs suggest the possible autonomous regulation of ado and aar. The complex transcriptional organization of the alkane synthesis gene cluster has possible metabolic implications and should be considered when manipulating the expression of these genes in

An approach regarding aging management program for concrete containment structure at the Gentilly-2 Nuclear Power Plant

Energy Technology Data Exchange (ETDEWEB)

Chenier, J-O.; Komljenovic, D., E-mail: Chenier.jean-olivier@hydro.qc.ca [Nuclear Power Plant Gentilly-2, Becancour, Quebec (Canada); Gocevski, V. [Hydro-Quebec Equipment, Structural Dept., Quebec (Canada); Picard, S.; Chretien, G. [Nuclear Power Plant Gentilly-2, Becancour, Quebec (Canada)

2012-07-01

The current paper presents the approach used by the Gentilly-2 Nuclear Power Plant, Hydro-Quebec, in elaborating a specific Aging Management Program (AMP) for its concrete containment structure. It is developed as a part of preparation activities for the plant refurbishment project. The specificity of the AMP consists in addressing Alkali-Aggregate Reaction (AAR) degradation mechanism which is not well known in the nuclear power industry. HQ developed a numerical model based on finite elements for assessing the concrete containment structure behaviour under the impact of AAR and other relevant degradation mechanisms. Such predictions enable a better targeting of corrective and mitigating actions during the second cycle of the G-2 operation while required. (author)

Noormees paneb Kanepi kooli tantsima / Milvi Hirvlaane

Index Scriptorium Estoniae

Hirvlaane, Milvi

2006-01-01

Tantsupedagoog Aare Laine tegevusest Kanepi gümnaasiumis, kus ta on lapsed esimesest kuni viimase klassini tantsima pannud. Tema viimaseid tantsuhitte "Chicken Power" teenis Koolitantsu finaalis eripreemia

Plasma Levels of Dimethylarginines in Preterm Very Low Birth Weight Neonates: Its Relation with Perinatal Factors and Short-Term Outcome

Directory of Open Access Journals (Sweden)

Rob M. Moonen

2014-12-01

Full Text Available Endogenously produced inhibitors of nitric oxide (NO synthase, in particular asymmetric dimethylarginine (ADMA, are currently considered of importance in various disease states characterized by reduced NO availability. We investigated the association between plasma levels of ADMA, symmetric dimethylarginine (SDMA, l-arginine, and citrulline and perinatal factors and outcome in 130 preterm (gestational age ≤30 weeks very low birth weight (VLBW, <1500 g infants. Plasma samples were collected 6–12 h after birth. We did not find significant correlations between ADMA, SDMA, l-arginine, and citrulline levels and gestational age or birth weight. However, the arginine:ADMA ratio (AAR, a better indicator of NO availability than either arginine or ADMA separately was positively correlated with gestational age. ADMA and arginine levels were not significantly different between males and females but males showed a negative correlation between ADMA levels and gestational age. Perinatal factors such as preeclampsia, chrorioamnionitis, prolonged rupture of membranes, or form of delivery did not significantly alter dimethylarginine levels or AAR. In contrast, the AAR was significantly reduced in the infants with respiratory distress, mechanical ventilation, and systemic hypotension Therefore, our data suggest that altered NO availability may play a role in the respiratory and cardiovascular adaptation in preterm VLBW infants.

Age estimation based on aspartic acid racemization in human sclera.

Science.gov (United States)

Klumb, Karolin; Matzenauer, Christian; Reckert, Alexandra; Lehmann, Klaus; Ritz-Timme, Stefanie

2016-01-01

Age estimation based on racemization of aspartic acid residues (AAR) in permanent proteins has been established in forensic medicine for years. While dentine is the tissue of choice for this molecular method of age estimation, teeth are not always available which leads to the need to identify other suitable tissues. We examined the suitability of total tissue samples of human sclera for the estimation of age at death. Sixty-five samples of scleral tissue were analyzed. The samples were hydrolyzed and after derivatization, the extent of aspartic acid racemization was determined by gas chromatography. The degree of AAR increased with age. In samples from younger individuals, the correlation of age and D-aspartic acid content was closer than in samples from older individuals. The age-dependent racemization in total tissue samples proves that permanent or at least long-living proteins are present in scleral tissue. The correlation of AAR in human sclera and age at death is close enough to serve as basis for age estimation. However, the precision of age estimation by this method is lower than that of age estimation based on the analysis of dentine which is due to molecular inhomogeneities of total tissue samples of sclera. Nevertheless, the approach may serve as a valuable alternative or addition in exceptional cases.

Julia on elus / Ivika Sillar

Index Scriptorium Estoniae

Sillar, Ivika, 1934-

2011-01-01

VAT-teatri "Nisa" (Marjorie Shostaki raamatu põhjal), dramatiseerija, lavastaja ja esitaja Katariina Unt, kaaslavastaja Aare Toikka, muusikaline kujundaja ja esitaja Tanel Ruben. Esietendus 15. aprillil Rahvusraamatukogu teatrisaalis

Siim Nestor soovitab : Magnets. Kõigem ruudus / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2002-01-01

31. mail toimub klubis Hollywood Cafe de la Souli üritus Magnets, külalisteks lauljad Kenny Bobien, Su Su ja DJ Shuji Hiroso. 1. juunil Von Krahlis Saaremetsa ja Tõnso esitletav Kõigem ruudus pidu

Anneli Remme soovitab : Prima la donna / Anneli Remme

Index Scriptorium Estoniae

Remme, Anneli, 1968-

2002-01-01

Rahvusooperis Estonia etenduvad 25. mail Straussi ooper "Salome", 23. mail ballett "Cassandra", 24. mail de Falla hispaania-eksootiline ooper "Lühike elu", 25. mail Carl Orffi "Tark naine", 26. mail Shtshedrini ballett "Anna Karenina" ja Bizet' ooper "Carmen"

Siim Nestor soovitab : lack of Eoins / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2008-01-01

Väikefirma Seksound annab sel nädalavahetusel välja Viljandi indiebändi Lack of Eoins esikplaadi "Echo Group" (plaadiesitlused 11. dets. Tallinnas Von Krahlis ja 12. dets. Tartus Genialistide klubis, esinevad ka Ans. Andur ja Popidiot, plaate keerutavad Hannes Praks ja Taavi Laatsit)

Siim Nestor soovitab : Teenage Kicks. Bassikultuur / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2005-01-01

Rockmuusikaüritusest "Teenage Kicks" 11. märtsil Von Krahlis. Üritusest "Bassikultuur" 12. märtsil Von Krahlis (oma esimest heliplaati "Occam's Razor" esitleb soome plaadifirma Nine2Five artist Infekto)

Siim Nestor soovitab : Hea Uus Heli / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2007-01-01

Üritustest Tallinnas muusikafestivalist HUH raames: "Odessa Pop" 4. okt., Pedigree remix-albumi "Ghosts and Corpses" esitlusest 5. okt. Kultuurikatlas, "Krill" 5. okt. Von Krahlis, Cluster ja Analogue Birds 6. okt. Glehni lossis

TV-Ekspress soovitab : Magik Markers Tallinnas ja Tartus

Index Scriptorium Estoniae

2008-01-01

Müra-rock'i viljelevast USA duost Magik Markers (ansambel osaleb režissöör Veiko Õunapuu uue mängufilmi "Püha Tõnu kiusamine" võtetel ja annab kaks kontserti - 13. nov. Tallinnas klubis Tapper ja 15. nov. koos ansamblitega Stella ja Chungin & Strap-On Faggots Tartus klubis Trehv). Heliplaadist "Boss

DVD. Margit Tõnson soovitab : "Libahundi needus" / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2006-01-01

ETV levitab DVD-l mängufilmi "Libahundi needus" : stsenaristid Margus Kasterpalu, Ilmar Raag ja Rainer Sarnet : režissöör Rainer Sarnet : osades Katariina Lauk, Rene Reinumägi : Shop of Dreams - Eesti Televisioon 2005

Mari Laaniste soovitab : "Rock on Screen" / Mari Laaniste

Index Scriptorium Estoniae

Laaniste, Mari, 1977-

2008-01-01

5.-11. juulini Tallinnas kinos Sõprus toimuvast muusikafilmide nädalast "Rock on Screen". Programmis on Julian Schnabeli kontsertfilm "Lou Reed's Berlin" (2007), Julien Temple'i "Tulevik on veel kirjutamata" (2007, pühendatud Joe Strummeri mälestusele), Anton Corbijni draama "Control" Joy Divisoni liidrist Ian Curtisest, JP Siili mängufilm "Hurriganes" (2007, soome rockansamblist) ja Peeter Urbla muusikafilm "Shlaager" (1983, filmi kangelannat kehastab Els Himma)

Siim Nestor soovitab : Odessa Pop. Neoandertals / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2007-01-01

Indieüritusest Odessa Pop 17. veebr. Tallinnas baar-klubis Juuksur. Ultrabrutaalse death-metali duo Neoandertals heliplaadi "Neoandertals Were Master Butchers" esitluskontserdist 17. veebr. Tallinnas KuKu klubis

Siim Nestor soovitab : Toimub selliseid asju... / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2005-01-01

Ameerika ansambel Tha Alkaholiks üritusel "Hip Hop Café" 4. nov. klubis Hollywood, ansambel The Wailers üritusel "The Spirit of Bob Marley" 5. nov. klubis Amigo, hiphopmuusika üritus 9. nov. klubis Privé, üritusel "WHA!?" 5. nov. Rakveres esitlusel uus duubelkogumik "Higha Collection 5"

Siim Nestor soovitab : Goldie. Chris Simmonds / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2002-01-01

Drum'n'bassi esimese superstaari Goldie esinemisest 16. nov. Circulation-sarja peol Lillepaviljonis Tallinnas. Londoni diskori Chris Simmondsi esinemistest 15. nov. Tartu klubis Tallinn ja 16. nov. Tallinnas kohvikus Moskva

'Tehisintellekt' (Alien Intelligence) : Heie Treier soovitab / Heie Treier

Index Scriptorium Estoniae

Treier, Heie, 1963-

2000-01-01

Helsingis 'Kiasmas' 11.II-28. V avatud suurprojekt, millele kuraator Erkki Huhtamo valis 18 kunstnikku üle maailma, esitab küsimusi inimese ja arvuti vahekorra kohta. 4.-5. III toimub konverents 'Tehisintellekti arheoloogia' ning Tehisintellekt ja meediakunst'. Vahepeal hollandi kunstniku Arthur Elssenari roboti Huge Harry performance jm.

49 CFR 179.7 - Quality assurance program.

Science.gov (United States)

2010-10-01

... means to detect any nonconformity in the manufacturing, repair, inspection, testing, and qualification... nonconformities. (8) Provisions indicating that the requirements of the AAR Specifications for Tank Cars (IBR, see...

Saaremaa politseijuht pensionile / Andres Sepp

Index Scriptorium Estoniae

Sepp, Andres, 1976-

2005-01-01

Kuressaare politseijaoskonna ülemkomissar Ants Ley esitas politseiametile lahkumisavalduse. Väidetavalt on nimetatud ühe võimaliku politseijuhikandidaadina Lääne prefektuuri teenistusosakonna komissari Aare Alliku nime. Lisa: Ants Ley

Routine blood tests to predict liver fibrosis in chronic hepatitis C.

Science.gov (United States)

Hsieh, Yung-Yu; Tung, Shui-Yi; Lee, Kamfai; Wu, Cheng-Shyong; Wei, Kuo-Liang; Shen, Chien-Heng; Chang, Te-Sheng; Lin, Yi-Hsiung

2012-02-28

To verify the usefulness of FibroQ for predicting fibrosis in patients with chronic hepatitis C, compared with other noninvasive tests. This retrospective cohort study included 237 consecutive patients with chronic hepatitis C who had undergone percutaneous liver biopsy before treatment. FibroQ, aspartate aminotransferase (AST)/alanine aminotransferase ratio (AAR), AST to platelet ratio index, cirrhosis discriminant score, age-platelet index (API), Pohl score, FIB-4 index, and Lok's model were calculated and compared. FibroQ, FIB-4, AAR, API and Lok's model results increased significantly as fibrosis advanced (analysis of variance test: P fibrosis score in chronic hepatitis C compared with other noninvasive tests. FibroQ is a simple and useful test for predicting significant fibrosis in patients with chronic hepatitis C.

A 9,000-year-old caribou hunting structure beneath Lake Huron.

Science.gov (United States)

O'Shea, John M; Lemke, Ashley K; Sonnenburg, Elizabeth P; Reynolds, Robert G; Abbott, Brian D

2014-05-13

Some of the most pivotal questions in human history necessitate the investigation of archaeological sites that are now under water. Nine thousand years ago, the Alpena-Amberley Ridge (AAR) beneath modern Lake Huron was a dry land corridor that connected northeast Michigan to southern Ontario. The newly discovered Drop 45 Drive Lane is the most complex hunting structure found to date beneath the Great Lakes. The site and its associated artifacts provide unprecedented insight into the social and seasonal organization of prehistoric caribou hunting. When combined with environmental and simulation studies, it is suggested that distinctly different seasonal strategies were used by early hunters on the AAR, with autumn hunting being carried out by small groups, and spring hunts being conducted by larger groups of cooperating hunters.

Oral cancer statistics in India on the basis of first report of 29 population-based cancer registries

Science.gov (United States)

Sharma, Swati; Satyanarayana, L; Asthana, Smitha; Shivalingesh, KK; Goutham, Bala Subramanya; Ramachandra, Sujatha

2018-01-01

Objectives: To summarize and provide an overview of age-specific oral cancer incidence reported in 29 population-based cancer registry in India. Materials and Methods: Secondary data on age-adjusted rates (AARs) of incidence of oral cancer and other associated sites for all ages (0–75 years) were collected from the report of the National Cancer Registry Programme 2012–2014 in 29 population-based control registries. Results: Among both males and females, mouth cancer had maximum Age adjusted incidence rates (64.8) in the central zone, while oropharynx cancer had minimum AAR (0) in all regions. Conclusion: Oral cancer incidence increases with age with typical pattern of cancer of associated sites of oral cavity seen in the northeast region. PMID:29731552

Pictures of fear and horror / Aare Pilv

Index Scriptorium Estoniae

Pilv, Aare, 1976-

2009-01-01

Autor lapsena unes hirmu põhjustanud piltidest. Ants Laikmaa pastellmaalist "Marie Underi portree (1904), selle sarnasusest Edvard Munchi kujutatud naistega ("Angstgefühl", 1896). Jüri Arraku illustratsioonist "Vanapagan" lasteraamatule "Suur Tõll" (1982). Otsa vaatavatest portreedest (Leonardo da Vinci "Mona Lisa")

Avastamata aare - Soomaa / Merle Adams, Rait Parts

Index Scriptorium Estoniae

Adams, Merle

2009-01-01

Euroopa Komisjoni algatatud rahvusvahelisest projektist EDEN "European Tourist Destinations of Exellence" ning selle raames toimunud Euroopa kontekstis loodusturismi sihtkohtade konkursi "European Destinations of Exellence" Eesti 2009. aasta sihtkoha tiitli võitnud Soomaa rahvuspargist

Karl Kello - elukutse olla saarlane / Aare Laine

Index Scriptorium Estoniae

Laine, Aare, 1951-

2004-01-01

Kuressaare Kuursaalis näidati kadripäeval nelja Ruta Celma ja Karl Kello kultuuriloolist dokumentaalfilmi : "Narr Jumala kojas" (2000), "Phaetonit otsides" (1999), "Eestlased Lätis" (2004) ja Kalevipoja temaatikat arendav "Küll siis Kalev..." (2004). Filmide operaator on Arvo Vilu. Artikli autor kõneleb Karl Kellost, tema Karja kiriku ja Kaali järve problemaatika arendustest peale filmide ka kirjasõnas

Veemajandus saab jõudsalt areneda / Aare Lepaste

Index Scriptorium Estoniae

Lepaste, Aare, 1970-

2004-01-01

8. detsembril kirjutasid seitsme vee-ettevõtte esindajad, KIK-i juhataja ja keskkonnaminister alla Eesti suurimale keskkonnaprojektile. Projekti eesmärk on viia omavalitsuste veemajanduse infrastruktuur vastavusse EL-i direktiividega.

Kivisildnik versus Under : lausuvad subjektid / Aare Pilv

Index Scriptorium Estoniae

Pilv, Aare, 1976-

2016-01-01

Sven Kivisildniku tekstidest, eriti "Märg Viktor" ja seal leiduvast intertekstuaalsusest. Artikli aluseks on 18.-19. apr. 1997 Otepääl TÜ ja TPÜ kirjandustudengite ja -magistrantide konverentsil 'Vaade sillalt' peetud ettekanne

India rentslimiljonär tegi ilma ka Oscarite peol / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2009-01-01

2008.a. filmiloomingu kaheksa Oscarit sai Danny Boyle'i mängufilm "Rentslimiljonär" ("Slumdog Millionaire"), produtsent Christian Colson. Lisatud Aare Tilga ja Timo Dieneri kommentaarid ning peamiste Oscarite nimekiri

"Миллионер из трущоб" покорил США / Тийт Туумалу

Index Scriptorium Estoniae

Туумалу, Тийт

2009-01-01

2008.a. filmiloomingu kaheksa Oscarit sai Danny Boyle'i mängufilm "Rentslimiljonär" ("Slumdog Millionaire"), produtsent Christian Colson. Lisatud Aare Tilga ja Timo Dieneri kommentaarid ning peamiste Oscarite nimekiri

Kohtumine küünlasäras. Dave Benton annab 12 jõulukontserti

Index Scriptorium Estoniae

2005-01-01

Tõnu Raadiku ja Aare Jaama kontserdist "Lumevarjude vahel" 11. dets. Pärnu Raekoja saalis. Uue albumi "Generations" üllitanud Dave Bentoni ja gospelkooride kontsertidest Eesti kirikutes (9. dets. Pärnu Eliisabeti kirikus)

Kehanarratiivid / Gregory Slick ; tõlk. Mari Laaniste

Index Scriptorium Estoniae

Slick, Gregory

2003-01-01

Reio Aare, Toomas Kalve, Margot Kase, Herkki-Erich Merila fotonäitus "The Fragments of Silence: Meditative moments in contemporary Estonian photography" 10.-26. IV New Yorgi galeriis Annex. Kuraator Rael Artel

Eestlased vigu parandamas ehk väikevormidest suurvormini, disainist reekviemini / Märt Kubo

Index Scriptorium Estoniae

Kubo, Märt, 1944-

2007-01-01

Eesti Kultuurfilmis valminud Juhan Aare (produtsent, autor) dokumentaalfilm NSVL rahvasaadikute kongressil 1989-1991 tegutsenud Eesti saadikute tegevusest ja iseseisvuse eest võitlemisest "Eestlased Kremlis" (režissöör Toomas Lepp)

Thoracic lymph node station recognition on CT images based on automatic anatomy recognition with an optimal parent strategy

Science.gov (United States)

Xu, Guoping; Udupa, Jayaram K.; Tong, Yubing; Cao, Hanqiang; Odhner, Dewey; Torigian, Drew A.; Wu, Xingyu

2018-03-01

Currently, there are many papers that have been published on the detection and segmentation of lymph nodes from medical images. However, it is still a challenging problem owing to low contrast with surrounding soft tissues and the variations of lymph node size and shape on computed tomography (CT) images. This is particularly very difficult on low-dose CT of PET/CT acquisitions. In this study, we utilize our previous automatic anatomy recognition (AAR) framework to recognize the thoracic-lymph node stations defined by the International Association for the Study of Lung Cancer (IASLC) lymph node map. The lymph node stations themselves are viewed as anatomic objects and are localized by using a one-shot method in the AAR framework. Two strategies have been taken in this paper for integration into AAR framework. The first is to combine some lymph node stations into composite lymph node stations according to their geometrical nearness. The other is to find the optimal parent (organ or union of organs) as an anchor for each lymph node station based on the recognition error and thereby find an overall optimal hierarchy to arrange anchor organs and lymph node stations. Based on 28 contrast-enhanced thoracic CT image data sets for model building, 12 independent data sets for testing, our results show that thoracic lymph node stations can be localized within 2-3 voxels compared to the ground truth.

2007. aasta raamatute tipp-10 / Kadri Kõusaar

Index Scriptorium Estoniae

Kõusaar, Kadri, 1980-

2007-01-01

Ilukirjandusest: Dovlatov, Sergei. Leivatöö. Võõramaa naine; Pilv, Aare. Näoline; Tsvetajeva, Marina. Elu tules : pihtimused; Kaplinski, Jaan. Seesama jõgi; García Márquez, Gabriel. Elada, et sellest jutustada

Interesting coin finds of 2005 / Mauri Kiudsoo

Index Scriptorium Estoniae

Kiudsoo, Mauri, 1973-

2006-01-01

2005. aasta arheoloogilistel kaevamistel avastatud müntidest väärivad eraldi märkimist nn. traatkopikad. Kõige rohkem traatkopikaid leiti Vastseliina piiskopilinnuselt. Üks traatkopikatest koosnenud aare leiti Koruste külast

Lugedes Pilve ja Pazi / Mathura

Index Scriptorium Estoniae

Mathura, pseud., 1973-

2007-01-01

Võrdlevalt Aare Pilve luulekogust "Näoline" (kirj. Tuum, 2007) ja Octavio Pazi luulekogust "Alati on olevik" (hispaania k. tlk. Ain Kaalep, Jaan Kaplinski, Asta Põldmäe ja Jüri Talvet, kirj. Perioodika, 1984)

Influence of mesostasis in volcanic rocks on the alkali-aggregate reaction

KAUST Repository

Tiecher, Francieli

2012-11-01

Mesostasis material present in the interstices of volcanic rocks is the main cause of the alkali-aggregate reaction (AAR) in concretes made with these rock aggregates. Mesostasis often is referred to as volcanic glass, because it has amorphous features when analyzed by optical microscopy. However, this study demonstrates that mesostasis in the interstitials of volcanic rocks most often consists of micro to cryptocrystalline mineral phases of quartz, feldspars, and clays. Mesostasis has been identified as having different characteristics, and, thus, this new characterization calls for a re-evaluation of their influence on the reactivity of the volcanic rocks. The main purpose of this study is to correlate the characteristics of mesostasis with the AAR in mortar bars containing basalts and rhyolites. © 2012 Elsevier Ltd. All rights reserved.

Influence of mesostasis in volcanic rocks on the alkali-aggregate reaction

KAUST Repository

Tiecher, Francieli; Dal Molin, Denise Carpena Coitinho; Gomes, Má rcia Elisa Boscato; Hasparyk, Nicole Pagan; Monteiro, Paulo José Meleragno

2012-01-01

Mesostasis material present in the interstices of volcanic rocks is the main cause of the alkali-aggregate reaction (AAR) in concretes made with these rock aggregates. Mesostasis often is referred to as volcanic glass, because it has amorphous features when analyzed by optical microscopy. However, this study demonstrates that mesostasis in the interstitials of volcanic rocks most often consists of micro to cryptocrystalline mineral phases of quartz, feldspars, and clays. Mesostasis has been identified as having different characteristics, and, thus, this new characterization calls for a re-evaluation of their influence on the reactivity of the volcanic rocks. The main purpose of this study is to correlate the characteristics of mesostasis with the AAR in mortar bars containing basalts and rhyolites. © 2012 Elsevier Ltd. All rights reserved.

Hidden State Conditional Random Field for Abnormal Activity Recognition in Smart Homes

Directory of Open Access Journals (Sweden)

Yu Tong

2015-03-01

Full Text Available As the number of elderly people has increased worldwide, there has been a surge of research into assistive technologies to provide them with better care by recognizing their normal and abnormal activities. However, existing abnormal activity recognition (AAR algorithms rarely consider sub-activity relations when recognizing abnormal activities. This paper presents an application of the Hidden State Conditional Random Field (HCRF method to detect and assess abnormal activities that often occur in elderly persons’ homes. Based on HCRF, this paper designs two AAR algorithms, and validates them by comparing them with a feature vector distance based algorithm in two experiments. The results demonstrate that the proposed algorithms favorably outperform the competitor, especially when abnormal activities have same sensor type and sensor number as normal activities.

Kalvi mõisas algas Seitsme Linna muusikafestival / Ago Gashkov

Index Scriptorium Estoniae

Gashkov, Ago

2004-01-01

Festivalist Seitsme Linna Muusika 18.-25. juulini (kunstiline juht Aare Tammesalu) Kalvi mõisas, Narva Aleksandri kirikus, Lüganuse kirikus, Kohtla-Järve Linnagaleriis, Sillamäel, Narva-Jõesuu Valges pargis ja Jõhvi Mihkli kirikus

Muusikalised maiuspalad raekojas

Index Scriptorium Estoniae

2009-01-01

26. juulil Pärnu raekojas toimuvast kontserdist "Grande Serenade", esitusel Johann Hummeli serenaadid (Grande Serenade), esinevad Arvo Leibur (viiul), Heiki Mätlik (kitarr), Madis Kari (klarnet), Aare Tammesalu (tšello) ja Tarmo Eespere (klaver)

Kriisikoldeid kustutab (teatri)mäng / Rait Avestik

Index Scriptorium Estoniae

Avestik, Rait, 1974-

2010-01-01

Itaallaste Nino d’Introna ja Giacomo Ravicchio teksti põhjal valminud seiklusloost „Robinson & Crusoe”, tõlkinud Kirke Org, lavastanud Aare Toikka. Esietendus 27. nov. 2009 VAT-teatris. Mängivad Meelis Põdersoo ja Ago Soots

EAS vahendas mullu Harjumaale 47 miljonit krooni toetusi / Allar Korjas

Index Scriptorium Estoniae

Korjas, Allar

2005-01-01

Möödunud aastal jõudis EAS- i vahendusel alustavate ja tegutsevate ettevõtete ning regionaalse arengu toetamiseks Harjumaale 47,1 miljonit krooni. Tabel. Vt. samas: Aare Ets. Regionaalne koostöö Harjumaal on oluline

Kruuda, Vichmann ja Kilp kavandavad Rocca al Maresse tervisemetropoli / Raigo Neudorf

Index Scriptorium Estoniae

Neudorf, Raigo

2007-01-01

Rocca al Mare Suurhalli uued omanikud Aare Kilp, Marcel Vichmann ja Oliver Kruuda plaanivad suurhalli lähedusse rajada suure ja uuelaadse vabaaja- ja spordikeskuse. Vt. samas: Kasumisse jõudmist takistab laenukoorem; Külastajate arv kasvab

"Rudi" polutshil glavnõi priz

Index Scriptorium Estoniae

2006-01-01

Lastefilm "Ruudi" (stsenaristid Katrin Laur, Aare Toikka, Aarne Mägi : režissöör Katrin Laur : nimiosas lapsnäitleja Paul Oskar Soe) sai Tokyo 14. lastefilmide festivalil Kodomotachino parima mängufilmi auhinna

Grand prix / J. U.

Index Scriptorium Estoniae

J. U.

2006-01-01

Lastefilm "Ruudi" (stsenaristid Katrin Laur, Aare Toikka, Aarne Mägi : režissöör Katrin Laur : nimiosas lapsnäitleja Paul Oskar Soe) sai Tokyo 14. lastefilmide festivalil Kodomotachino parima mängufilmi auhinna

"Ruudi" võitis Tokyos

Index Scriptorium Estoniae

2006-01-01

Lastefilm "Ruudi" (stsenaristid Katrin Laur, Aare Toikka, Aarne Mägi : režissöör Katrin Laur : nimiosas lapsnäitleja Paul Oskar Soe) sai Tokyo 14. lastefilmide festivalil Kodomotachino parima mängufilmi auhinna

ORF Alignment: NC_002939 [GENIUS II[Archive

Lifescience Database Archive (English)

Full Text Available NC_002939 gi|39996821 >1v7zA 3 252 1 232 3e-42 ... ref|NP_952772.1| creatinine amidoh...ydrolase [Geobacter sulfurreducens PCA] ... gb|AAR35099.1| creatinine amidohydrolase [Geobacter ...

"Ruudi" - helge muinasjutt lastele, iroonia vanematele / Teelemari Loonet

Index Scriptorium Estoniae

Loonet, Teelemari, 1987-

2006-01-01

Lastefilm "Ruudi" : stsenaristid Aare Toikka, Aarne Mägi : režissöör Katrin Laur : nimiosas lapsnäitleja Paul Oskar Soe : operaator Rein Kotov : Allfilm - MRP Matila Röhr Productions - Schmidtz Katze Filmkollektiv 2006

Adding an Intelligent Tutoring System to an Existing Training Simulation

National Research Council Canada - National Science Library

Stottler, Richard H; Jensen, Randy; Pike, Bill; Bingham, Rick

2006-01-01

...). It was determined that the addition of an Intelligent Tutoring System (ITS) to BC2010 would off-load the instructor from these duties and allow the students to execute scenarios without requiring an instructor for the AAR...

Reval Hotel Lietuva Vilniuses : Konstitucijos pr. 20 / Piret Lindpere

Index Scriptorium Estoniae

Lindpere, Piret, 1963-

2004-01-01

Vilniuse hotelli "Lietuva" renoveerimine. Arhitektuurse projekti koostaja Rootsi arhitektuuribüroo AB SWECO (arhitektid Aare Saks, Nils Palm. Sisekujundus: Vaikla Disain AS (Katrin ja Argo Vaikla, Liis Lindvere, Peeter Loo). Kommenteerivad Argo ja Katrin Vaikla. 3 ill

Perception of Community Health Extension Services among Women ...

African Journals Online (AJOL)

UNIBEN

communities were: Sentu, Ile-Apa, Budo-. Aare, Alalubosa ... community for at least six months in order to be used to the ... edition (SPSS-18). Data were ..... Manual for Governments and Other ... gazette. Legal Notice on Publication of.

NCBI nr-aa BLAST: CBRC-MDOM-02-0463 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-MDOM-02-0463 ref|NP_954911.1| large tegument protein [Bovine herpesvirus 5] gb...|AAR86125.1| UL36 very large tegument protein [Bovine herpesvirus 5] NP_954911.1 8e-11 34% ...

Self-Assessment Based Mini-After Action Review (SAMAAR) Methodology: Developmental Application to Division Artillery Staff Training

National Research Council Canada - National Science Library

Mirabella, Angelo

1998-01-01

.... In the SAMAAR approach, trainees, at the end of an exercise day or shift fill out rating forms to assess the units training progress and then convene with their completed forms to participate in a mini-AAR...

Durability and acoustics of concrete with slag of cupola furnace as fine aggregate replacement

Directory of Open Access Journals (Sweden)

Ricardo Alfredo Cruz Hernández

2015-01-01

Full Text Available In this paper, it was evaluated the performance of concrete with crushed slag of cupola furnace (SCF as sand replacement in percentages of 0 %, 10 %, 15 % and 20 %, subjected to accelerated chemical attacks of carbonation, sulfation and alkali-aggregate reaction (AAR. The sound absorption characteristics of the material were determined through the sound absorption coefficient (α, and the noise reduction coefficient (NRC. Carbonation was evaluated through a closed camera with the 70 % concentration of carbon dioxide and conditions of relative humidity between 50 % and 70 %. The results indicated that the penetration depth of CO2 is lower when greater the percentage of substitution is. To accelerate the attack by sulfates, specimens were immersed in aqueous solution of sodium sulfate anhydrous (Na2SO4 1N with cycles of wetting and drying. It determined that the impairment presented in concrete paste is directly proportional to the percentage of sand replacement. The acceleration of the AAR in the concrete was carried out by immersing specimens in an aqueous solution of sodium hydroxide (NaOH for 16 days. The test concluded that the inclusion of SCF is not favorable for AAR. The measurement of sound absorption coefficient was taken by the method of impedance tube, relating minimum and maximum values of stationary wave amplitude. The results showed that SCF with higher sand replacement are favorable for the noise absorption in buildings.

Kivirähk korraga kahel laval / Tiiu Laks

Index Scriptorium Estoniae

Laks, Tiiu, 1984-

2009-01-01

31. jaan. Ugalas esietenduvast Andrus Kivirähki esimesest näidendist "Vanamehed seitsmendalt" Peeter Tammearu lavastuses ja VAT Teatris lavale jõudvast Kivirähki uusimast tükist "Ingel, ingel, vii mind taeva" Aare Toikka lavastuses

Homo soveticusest eesti inimeseni / Mart Niklus

Index Scriptorium Estoniae

Niklus, Mart-Olav, 1934-

2004-01-01

Autori mõtisklused Eesti lipust, antikommunistlikust vastupanuliikumisest nõukogude ajal, Nõukogude okupatsiooni käsitlevatest muuseumidest. Sisaldab artiklit "Rahvuslipp "Vanemuise" katusel ja Aare Printsi kohtuasi", allikas : Lisandusi mõtete ja uudiste vabale levikule Eestis. I kogu. Stockholm, 1984

ORF Alignment: NC_002128 [GENIUS II[Archive

Lifescience Database Archive (English)

Full Text Available ing protein SopA [Large-insert cloning vector ... pSMART VC] gb|AAR05665.1| stabilization of plasmid ... ... protein A [Salmonella typhimurium] gb|AAO61293.1| ParA ... [BAC cloning vector pEBAC190G

'1900 ئ kunst ristteedel' : Harry Liivrand soovitab / Harry Liivrand

Index Scriptorium Estoniae

Liivrand, Harry, 1961-

2000-01-01

19. sajandi lõpu ئ 20. sajandi alguse kunsti retrospektiivnäitus 3. apr.-ni Royal Academy of Arts'is Londonis. Ülevaade Euroopa, Ameerika ja Jaapani kunstist kogu oma stiililises ja hoiakulises vastuolulisuses: realism, postimpressionism, juugend, sümbolism, hilisromantism, akademism.

Super Bowli teooria soovitab aktsiaid osta / Fredy-Edwin Esse

Index Scriptorium Estoniae

Esse, Fredy-Edwin

2011-01-01

Super Bowli teooria kohaselt tõuseb Dow Jones, kui võidab algupärase NFL-i meeskond. MarketWatchi peaökonomist Irwin Keller avaldab arvamust, miks tasuks investoritel Super Bowli tulemustele tähelepanu pöörata

Siim Nestor soovitab : DJ Suv. Reaalsessioonid Tartus / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2001-01-01

DJ Suv esineb koos MC Guyvoriga üritusel Dzhungli kellad 21. detsembril Kunstiakadeemias, hiljaaegu valmis tema soolo debüüt-LP "Desert Rose". 21. detsembril Tartu klubis Illegaard toimuvast CD-kogumiku "Tallinn: psühhedeelne linn" esitlus-kontsert-peost

Anneli Remme soovitab : Eesti mõisad 2008 / Anneli Remme

Index Scriptorium Estoniae

Remme, Anneli, 1968-

2008-01-01

15.-24. augustini toimub kuues Eesti mõisas kontsertetenduste sari "Eesti mõisad 2008", kus esinevad barokkansambel Corelli Consort ja Fine 5 Tantsuteater. Mõisate ajalugu tutvustab Jüri Kuuskemaa

Siim Nestor soovitab : Elektroakustiline kontsert. Supreme Võrus / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2002-01-01

21. juunil Tallinnas Kalinini tehases installatsiooninäituse Four Songs For Siivi raames toimuvast elektroakustilisest eksperiment-kontserdist, kus peaosas prantslane Mathieu Werchowski. Diskost Võru rannabaaris 21. juunil

DVD. Kalmer Saar soovitab: "Casanova", "Fellini's Casanova" / Kalmer Saar

Index Scriptorium Estoniae

Saar, Kalmer

2006-01-01

Kaks DVD-d mängufilmidega seiklejast Giovanni Giacomo Casanovast (1725-1798) : "Casanova", režissöör Lasse Hallström : Ameerika Ühendriigid 1995 ja "Federico Fellini Casanova" : režissöör F. Fellini, Itaalia 1976. Ka filmi lisadest DVD-l

Siim Nestor soovitab : Teenage Kicks. Bängin / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2002-01-01

12. aprillil alustatakse Pif-Pafi klubis live-muusikale orienteeritud muusikaõhtute sarjaga Teenage Kicks. Esinevad ansamblid BAP ja Id Rev ( andis 2001. aasta suvel välja albumi "Sina Ei"). Bängin on väike technopidu 13. apr. Wimbledonis, kus valivad technot Erkki Tero, Orav, Ilmar Kerm ja Raul Saaremets

DVD. Piret Tamm soovitab : "Mootorrattapäevikud" / Piret Tamm

Index Scriptorium Estoniae

Tamm, Piret, 1966-

2006-01-01

Mängufilm Che Guevarast "Mootorratta päevikud" ("Diarios de motocicleta") : režissöör Walter Salles : Ameerika Ühendriigid - Saksamaa - Suurbritannia - Argentiina - Tšiili - Peruu 2004. Kriitikat ka firma V&K Holding DVD kvaliteedi kohta

Saksa ekspert soovitab EAS-i erastada / Toivo Tänavsuu

Index Scriptorium Estoniae

Tänavsuu, Toivo

2003-01-01

Saksa spetsialisti hinnangul tuleks Eestis erastada Ettevõtluse Arendamise Sihtasutus, põllumajanduse registrite ja informatsiooni amet ning teised struktuurifondide rakendusüksused. Saksamaal on enamik 50 rakendusüksusest eraomandis

Siim Nestor soovitab : 1öö%. Tahira. Wha!? 2006

Index Scriptorium Estoniae

2006-01-01

HUHi klubiõhtust "1öö%" 3. nov. Von Krahlis. Brasiilia diskor Tahira 3. nov. Tartus Lutsu teatrimajas peol "Jazz Lessions" ja 4. nov. Tallinnas Von Krahlis. Uue muusika festivalist "Wha!? 2006" 4. nov. Rakvere teatri majas

Anneli Remme soovitab : Kreegi Reekviem uues seades / Anneli Remme

Index Scriptorium Estoniae

Remme, Anneli, 1968-

2007-01-01

Eesti Filharmoonia Kammerkoori ja inglise organisti ning helilooja Christopher Bowers-Broadbenti kontserdist 8. veebr. Tartu Jaani kirikus, 9. veebr. Haapsalu Toomkirikus ja 10. veebr. Tallinna Niguliste kirikus

Anneli Remme soovitab : maailmaesiettekanne Eesti Filharmoonia Kammerkoorilt / Anneli Remme

Index Scriptorium Estoniae

Remme, Anneli, 1968-

2002-01-01

13. sept. Rakvere kirikus ja 14. sept. Tallinna Metodisti kirikus toimuvast Eesti Filharmoonia Kammerkoori kontserdist, kus esitusele tuleb Howard Skemptoni "Rise up, my love". Kontserdil kõlab ka Britteni, Tippetti, Pärdi, Desprez' ja Gesualdo muusika

Siim Nestor soovitab : Ugly Duckling. Adam F / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2006-01-01

Ameerika hip-hop-ansambli Ugly Duckling'i heliplaadi "Bang for the Buck"esitluskontserdist 9. nov. Tallinna klubis Hollywood. Inglise diskor Adam F drum'n'bass-üritusel "Sin City" 10. nov. Tartu linna klubis Tallinn

Euroopa Komisjon soovitab IASi senisest laiemat kasutamist / Ago Vilu

Index Scriptorium Estoniae

Vilu, Ago, 1967-

2000-01-01

Euroopa Komisjon avaldas 13. juunil 2000 pöördumise Euroopa Nõukogu ja Parlamendi poole, milles tehakse ettepanek muuta hiljemalt 2005. aastast rahvusvaheliste raamatupidamisstandardite (IAS) rakendamine kohustuslikuks kõikidele Euroopa Liidu börsiettevõtetele

Siim Nestor soovitab : Tulebki tagasi...ja veel / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2003-01-01

Üritusest kohvik-klubis Moskva 1. juunil, esinejateks Louie Vega, Dave Storm ja Raul Saaremets. Üritusest Jazz'N Motion Eesti Näituste Sinises Paviljonis 29. mail, esinejateks The Gotan Projekt ja Kimmo Pohjonen. Üritusest Barclay Dance Blend klubis BonBon 31. mail, esinejateks DJ Marine, Rhytm Doktor ja Saaremets. Üritusest 3. juunil Von Krahlis, külaliseks Electronicat

Heie Treier soovitab : Sakraalarhitektuur ja Portugali kunst / Heie Treier

Index Scriptorium Estoniae

Treier, Heie, 1963-

2001-01-01

Näitused arhitektuuri- ja kunstikeskuses Rotermanni Soolaladu: "Moodsad kirikud: Eesti 1920.-30. aastate sakraalarhitektuur" ja Portugali-Eesti ühisnäitus "High Input Low Noise", eksponeeritud videod vastava helitaustaga

Soome ekspert soovitab Eestil riigiametnike armeed vähendada

Index Scriptorium Estoniae

2010-01-01

Soome rahandusministeeriumi riigihalduse asekantsler Juhani Turunen ja OECD valitsussektori ja territoriaalse arengu ekspert Edwin Lau soovitavad Eestil eeskuju võtta Soomest ja vähendada riigiametnike hulka, samuti arendada koostööd keskvalitsuse ja omavalitsuste vahel

ORF Alignment: NC_003075 [GENIUS II[Archive

Lifescience Database Archive (English)

Full Text Available NC_003075 gi|30692533 >3ullA 5 115 1 104 8e-18 ... ref|YP_063478.1| ssb1 [Campylobact...er jejuni] gb|AAR29567.1| ssb1 [Campylobacter ... jejuni] ... Length = 104 ... Query: 31 ... GQDSDVS

Composite Monopack for 120mm Mortar, With Plastic Pallet Adapters on a 42" x 53" Wooden Pallet, MIL-STD-1660 Tests, "Design Criteria for Ammunition Unit Loads", and Extreme Temperature Tests

National Research Council Canada - National Science Library

Dugan, Jeffery L

2005-01-01

... (AMSRD-AAR-AIL-P) to conduct MIL-STD-1660 Tests to determine if the composite monopack for the 120MM mortar, with plastic pallet adapters on a 42" x 53" wooden pallet, designed by US Army ARDEC and manufactured...

Lilleküla jalgpallistaadion = Lilleküla Football Stadium / Haldo Oravas

Index Scriptorium Estoniae

Oravas, Haldo, 1960-

2001-01-01

Arhitekt, projekti ja detailplaneeringu (AS Eesti Projekt, 1999) autor Haldo Oravas. Projekteerijad: ETP Grupp, projektijuht Aare Uusalu, arhitekt Peep Urb. Sisekujundaja Sirje Pohl. Projekt 2000-2001. 8 ill.: V korruse ja asendiplaan, tribüüni lõige, vaated

Kuidas lugeda "Meeste domineerimist"? / Patrick Champagne ; tlk. Marek Tamm

Index Scriptorium Estoniae

Champagne, Patrick

2005-01-01

Rets. rmt.: Bourdieu, Pierre. Meeste domineerimine. Tallinn, 2005. Kommenteerivad (lk. 12-14) Liina Lukas, Rein Ruutsoo (TLÜ õppejõud), Marina Grišakova, Aare Pilv, Airi-Alina Allaste, Raivo Vetik (TLÜ Õppejõud), Andres Härm, Voldemar Tomusk

Pal-tänava poisid" võitis Peterburis kõrge auhinna

Index Scriptorium Estoniae

2006-01-01

VAT Teater osales 4.-10. maini Peterburis VII rahvusvahelisel noorsooteatrite festivalil "Vikerkaar" lavastusega "Pál-tänava poisid" (autor Ferenc Molnár, lavastaja Aare Toikka) ja pälvis ühe peapreemiatest : auhinna parimale näitlejate ansamblile

Dosje festivalei : "Raduga". 4-10 maja 2006 g. Tjuz im. A. Brjantseva / Jelena Gorfunkel

Index Scriptorium Estoniae

Gorfunkel, Jelena

2006-01-01

4.-10. maini Peterburis toimunud VII rahvusvahelisest noorsooteatrite festivalist "Vikerkaar". Arvustatakse ka VAT Teatri lavastust "Pál-tänava poisid" (autor Ferenc Molnár, lavastaja Aare Toikka). Pälvis ühe peapreemiatest : auhinna parimale näitlejate ansamblile

Adept at adapting : contributions of sociology to agricultural research for small farmers in developing countries : in case of rice in the Dominican Republic

NARCIS (Netherlands)

Doorman, F.

1991-01-01

This book discusses possible contributions of sociology and anthropology to agricultural research. It is based on investigations carried out from 1981 to 1985 in the Dominican Republic in the Adaptive Agricultural Research (AAR) project, a cooperative effort between the Agricultural

LACK OF EFFECT OF AGE AND ANTIOXIDANT DEPLETION ON RESPIRATORY RESPONSES TO CONCENTRATED AMBIENT PARTICULATES (CAPS) IN RATS

Science.gov (United States)

2003 AAR PM MeetingParticulate Matter: Atmospheric Sciences,Exposure and the Fourth Colloquium on PM and Human HealthLACK OF EFFECT OF AGE AND ANTIOXIDANT DEPLETION ON RESPIRATORY RESPONSES TO CONCENTRATED AMBIENT PARTICULATES (CAPs) IN RATS. JA Dye, LC Walsh, C...

Glavnõi Oskar - "Stolknoveniju" / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2006-01-01

Kuidas ja miks juhtus, et 78. Ameerika Filmiakadeemia Oscari-tseremoonial kuulutati parimaks filmiks Paul Haggise "Kokkupõrge" ("Crash") seni üldiselt favoriidiks peetud Ang Lee "Brokebacki mäe" ("Brokeback Mountain") asemel. Lisatud arvamused, mille autoriteks Aare Tilk ja Ilmar Raag

Meri on mereriigi majanduskasvu eeldus / Aare-Maldus Uustalu

Index Scriptorium Estoniae

Uustalu, Aare-Maldus, 1935-

2005-01-01

Eesti majanduskasvu edukus merenduse ja siseveetranspordi arendamise valdkonnas sõltub mitte üksnes teadlaste panusest, vaid suurel määral riigiametnike töö kvaliteedist, nende suutlikkusest ja vastutustundest, leiab autor. Tabelid. Kaart

Molecular evidence of fungal signatures in the marine protist Corallochytrium limacisporum and its implications in the evolution of animals and fungi

Digital Repository Service at National Institute of Oceanography (India)

Manohar, C; Raghukumar, S.; Kasbekar, D.P.; Raghukumar, C

and ergosterol, in one of the isolates. These features, as well as the sterol C-14 reductase gene involved in the sterol pathway of animals and fungi were detected in the organism. Phylogenetic trees based on the α-AAR gene suggested that Corallochytrium...

ORF Alignment: NC_003070 [GENIUS II[Archive

Lifescience Database Archive (English)

Full Text Available NC_003070 gi|18397761 >1wocC 2 96 2 97 5e-15 ... ref|YP_063428.1| ssb1 [Campylobacter... ... gb|EAL55921.1| single-strand binding protein, putative ... [Campylobacter coli RM2228] gb|AAR29517.1| ssb1

Ruudi läheb Tokyosse / Olev Remsu

Index Scriptorium Estoniae

Remsu, Olev, 1947-

2006-01-01

Lastefilm "Ruudi" : stsenaristid Aare Toikka, Aarne Mägi : režissöör Katrin Laur : nimiosas lapsnäitleja Paul Oskar Soe : operaator Rein Kotov : Allfilm - MRP Matila Röhr Productions - Schmidtz Katze Filmkollektiv 2006. Lähemalt analüüsitakse stsenaariumi

Sellest, mis teiste eest varjatud / Rainer Sarnet

Index Scriptorium Estoniae

Sarnet, Rainer, 1969-

2000-01-01

USA mängufilmid "Tabamatu ilu" (American Beauty") : režissöör Sam Mendes : 1999 ja "Õnn" ("Happiness") : režissöör Todd Solondz : 1998. Lisa : Aare Ermeli koostatud režissööride lühielulood

Oscarite peost sai Marty triumf / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2007-01-01

Oscarite võitjad põhikategooriates. Suurim võitja oli Martin Scorsese oma filmiga "Kahe tule vahel" ("The Departed") - parim film, parim režissöör, parim stsenaarium, parim montaazh. Kommenteerivad Aare Tilk ja Timo Diener. Lisatud nimekiri "Oscari võitjad"

Cardiovascular magnetic resonance imaging of myocardial oedema following acute myocardial infarction

DEFF Research Database (Denmark)

Hamshere, Stephen; Jones, A Daniel; Pellaton, Cyril

2016-01-01

patients after successful primary percutaneous coronary intervention. 82 patients underwent a novel 3-slice SAX protocol and 85 patients underwent standard 10-slice SAX protocol. AAR was obtained by manual endocardial and epicardial contour mapping followed by a semi- automated selection of normal...

Prostate cell membrane chromatography-liquid chromatography-mass spectrometry for screening of active constituents from Uncaria rhynchophylla.

Science.gov (United States)

He, Jianyu; Han, Shengli; Yang, Fangfang; Zhou, Nan; Wang, Sicen

2013-01-01

Uncaria rhynchophylla is a traditional Chinese medicinal herb used to treat hypertension and convulsive disorders such as epilepsy. Rat prostate cell membrane chromatography combined with liquid chromatography-mass spectrometry (LC-MS) was used to identify active constituents from U. rhynchophylla extracts. Four compounds (corynoxeine, isorhynchophylline, isocorynoxeine and rhynchophylline) were discovered. Competitive binding assay results indicated that the four compounds were in direct competition at a single common binding site and interacted with α1A adrenergic receptors (α1A-AR) in a manner similar to tamsulosin. Affinity constant values of the four compounds binding with α1A-AR were also measured using rat prostate cell membrane chromatography (CMC). Finally, their pharmacodynamic effects were tested on rat caudal arteries. This CMC combined LC-MS system offers a means of drug discovery by screening natural medicinal herbs for new pharmacologically active molecules targeting specific receptors.

An Oral Selective Alpha-1A Adrenergic Receptor Agonist Prevents Doxorubicin Cardiotoxicity

Directory of Open Access Journals (Sweden)

Ju Youn Beak, PhD

2017-02-01

Full Text Available Summary: Alpha-1 adrenergic receptors (α1-ARs play adaptive and protective roles in the heart. Dabuzalgron is an oral selective α1A-AR agonist that was well tolerated in multiple clinical trials of treatment for urinary incontinence, but has never been used to treat heart disease in humans or animal models. In this study, the authors administered dabuzalgron to mice treated with doxorubicin (DOX, a widely used chemotherapeutic agent with dose-limiting cardiotoxicity that can lead to heart failure (HF. Dabuzalgron protected against DOX-induced cardiotoxicity, likely by preserving mitochondrial function. These results suggest that activating cardiac α1A-ARs with dabuzalgron, a well-tolerated oral agent, might represent a novel approach to treating HF. Key Words: alpha adrenergic receptors, anthracyclines, cardioprotection, catecholamines, heart failure

Kuidas kommenteerite hoolekogu rolli enda koolis? / Mihkel Rebane, Margus Leek, Hannes Astok ... [jt.

Index Scriptorium Estoniae

2011-01-01

Küsimusele vastavad Kiili gümnaasiumi direktor Mihkel Rebane, Mart Reiniku gümnaasiumi hoolekogu vilistlaste esindaja Margus Leek, riigikogulane, HTG hoolekogu liige Hannes Astok, Puurmani gümnaasium õpilasesinduse president Kertu Vahtra ja Saku gümnaasiumi hoolekogu esimees Aare Järvelaid

Eesti sumokamp ja esijudoka videolindil / Tarmo Teder

Index Scriptorium Estoniae

Teder, Tarmo, 1958-

1999-01-01

Dokumentaalfilmid maadlejatest : "Legend päikesest" : stsenarist, režissöör, toimetaja ja produtsent Aare Tilk : Eesti Telefilm 1999 ja "Tempo di valse" : käsikiri Hans Roosipuu ja Peeter Simm : režissöör Peeter Simm : Faama Film 1999

Personal Epistemology of Urban Elementary School Teachers

Science.gov (United States)

Pearrow, Melissa; Sanchez, William

2008-01-01

Personal epistemology, originating from social construction theory, provides a framework for researchers to understand how individuals view their world. The Attitudes About Reality (AAR) scale is one survey method that qualitatively assesses personal epistemology along the logical positivist and social constructionist continuum; however, the…

Kolm tähelepanuväärset bibliograafiat / Tiina Ritson

Index Scriptorium Estoniae

Ritson, Tiina, 1955-

2011-01-01

Arvustus: Uku Masing 100 : bibliograafia 1923-2009 / koost. Anneli Sepp. Tartu : Ilmamaa, 2010. Voldemar Panso bibliograafia / koost. Katre Riisalu, Eha Garšnek, Mari Sibul. Tallinn : Eesti Draamateater, 2010. Pilv, Aare. Juhan Viidingu ja Jüri Üdi bibliograafia // Juhan Viiding, eesti luuletaja. Tartu, 2010.

78 FR 54952 - Petition for Waiver of Compliance

Science.gov (United States)

2013-09-06

... improve safety and eliminate unnecessary costs to the industry. Through a limited pilot effort AAR intends... safe braking performance. The focus of this pilot will be the normal revenue service coal trains... through Friday, except Federal Holidays. Interested parties are invited to participate in these...

Armastust otsivad inimesed / Kristiina Davidjants

Index Scriptorium Estoniae

Davidjants, Kristiina, 1974-

2001-01-01

Paul Thomas Andersonist ja tema mängufilmidest "Kibe käsi" ("Hard Eight"), "Magnoolia" ("Magnolia") ja "Boogie Nights" : Ameerika Ühendriigid vastavalt 1996, 1999 ja 1997. Lisa : Aare Ermeli esitatud lühiandmed P. T. Andersoni kohta. Kokkuvõte inglise keeles lk. 96

Eesti lastefilm räägib üksikutest lastest ja üksikutest vanematest / Jürgen Rooste, Marko Martinson

Index Scriptorium Estoniae

Rooste, Jürgen, 1979-

2006-01-01

Lastefilm "Ruudi" : stsenaristid Katrin Laur, Aare Toikka, Aarne Mägi : režissöör Katrin Laur : nimiosas lapsnäitleja Paul Oskar Soe : produtsent Piret Tibbo-Hudgins : operaator Rein Kotov : kunstnik Toomas Hõrak : Allfilm - MRP Matila Röhr Productions - Schmidtz Katze Filmkollektiv 2006

77 FR 76169 - Quarterly Rail Cost Adjustment Factor

Science.gov (United States)

2012-12-26

....stb.dot.gov . Copies of the decision may be purchased by contacting the Office of Public Assistance...)] Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the AAR's proposed rebasing calculations and...

The South African Defence Force and Horse Mounted Infantry ...

African Journals Online (AJOL)

Jacques

2003-03-26

Mar 26, 2003 ... ranger and tracker in the Etosha National park after being offered the ... had a personal interest in the SADF horse stud farm at De Aar, and was a .... prudent to know the location of 'shonas'48, local wells and watering holes ...

76 FR 18073 - Track Safety Standards; Concrete Crossties

Science.gov (United States)

2011-04-01

... decomposition. FRA continues to believe that breaks, cracking, mechanical abrasion, or chemical reaction in... engineering performance, but was uneconomical. \\1\\ J.W. Weber, ``Concrete crossties in the United States... investigation,'' AAR, Engineering research division, Report No. ER-20 November 1961; and G.M. Magee and E. J...

75 FR 75963 - Export Trade Certificate of Review

Science.gov (United States)

2010-12-07

... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 92-9A001] Export Trade... Industries Association of America (``AIA'') (Application 92-9A001). SUMMARY: The U.S. Department of Commerce...: Accenture is now located in Chicago, IL, with controlling entity Accenture plc, Dublin, Ireland; AAR...

78 FR 5767 - Positive Train Control Systems (RRR)

Science.gov (United States)

2013-01-28

..., modify the default procedures for handling the en route failure of PTC systems, and allow automatic... seeks information sufficient to make a reasoned determination that benefits justify costs and therefore... practicability of the waiver process as an acceptable method of handling such operations. In the Petition, AAR...

77 FR 21311 - Locomotive Safety Standards

Science.gov (United States)

2012-04-09

... preparedness, alcohol and drug testing, locomotive engineer certification, and workplace safety. In 1980, FRA... Association (ATDA) Amtrak AAR Association of Railway Museums (ARM) Association of State Rail Safety Managers... Administration 49 CFR Parts 229 and 238 Locomotive Safety Standards; Final Rule #0;#0;Federal Register / Vol. 77...

49 CFR 171.7 - Reference material.

Science.gov (United States)

2010-10-01

.../publications.com; AAR Manual of Standards and Recommended Practices, Section C—Part III, Specifications for... Edition, March 1996 172.102. American Pyrotechnics Association (APA), P.O. Box 30438, Bethesda, MD 20824, (301) 907-8181, www.americanpyro.com: APA Standard 87-1, Standard for Construction and Approval for...

Journal of Child and Adolescent Mental Health - Vol 24, No 1 (2012)

African Journals Online (AJOL)

The theory of planned behaviour as a framework for predicting sexual risk behaviour in sub-Saharan African youth: A critical review · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Cleo Protogerou, Alan J Flisher, Leif Edvard Aarø, Catherine Mathews.

VAT teatril kaks uut noortelavastust / Tiiu Talvist

Index Scriptorium Estoniae

Talvist, Tiiu

2010-01-01

VAT teater panustab sel hooajal uutesse laste- ja noortelavastustesse: lisaks itaallaste Nino d’Introna ja Giacomo Ravicchio teksti põhjal valminud seiklusloole „Robinson & Crusoe” (lavastaja Aare Toikka), esietendub aprillis Mare Sabolotny noorte probleemidest kõnelev lavalugu „Kirjaklambritest vöö”. Lavastaja Rein Agur

Deklaratsioon = Declaration / Jaan Sõrra

Index Scriptorium Estoniae

Sõrra, Jaan, 1954-

2006-01-01

Konverentsi "580 päeva Euroopa Liidus " osalejate pöördumine. Vt ka vastused deklaratsioonile lk. 103-107 riigisekretär Heiki Loot, põllumajandusminister Ester Tuiksoo, haridus- ja teadusminister Mailis Reps, keskkonnaminister Villu Reiljan, Riigikogu kultuurikomisjon Olav Aarna, rahandusminister Aivar Sõerd ja Aare Järvan

Ärimehed tõid kuu ja päikese Narva-Jõesuusse

Index Scriptorium Estoniae

2009-01-01

2008. a. avatud Meresuu spaa-hotellist, mis ehitati nõukogudeaegse lõpetamata rajatise peale. Arhitektuurse lahenduse autor Andres Põime ja sisekujunduse autor Reet Põime arhitektuuribüroost Studio 3. Wellness-korruse sisekujundaja Liisi Murula. Purskkaevud-lillepeenrad kavandas Kersti Lootus. Omanikud: Aare Kööp, Rene Kuulmann

Application of a novel method for age estimation of a baleen whale and a porpoise

DEFF Research Database (Denmark)

Nielsen, Nynne H.; Garde, Eva; Heide-Jørgensen, Mads Peter

2013-01-01

Eyeballs from 121 fin whales (Balaenoptera physalus) and 83 harbor porpoises (Phocoena phocoena) were used for age estimation using the aspartic acid racemization (AAR) technique. The racemization rate (kAsp) for fin whales was established from 15 fetuses (age 0) and 15 adult whales where age...

Distinction of salvaged and infarcted myocardium within the ischaemic area-at-risk with T2 mapping

DEFF Research Database (Denmark)

Hammer-Hansen, Sophia; Ugander, Martin; Hsu, Li-Yueh

2014-01-01

values from T2 maps and signal intensities on T2-weighted images were measured in the corresponding areas. RESULTS: At both imaging time points, the T2 of the salvaged myocardium was longer than of remote (66.0 ± 6.9 vs. 51.4 ± 3.5 ms, P ...AIM: Area-at-risk (AAR) measurements often rely on T2-weighted images, but subtle differences in T2 may be overlooked with this method. To determine the differences in oedema between salvaged and infarcted myocardium, we performed quantitative T2 mapping of the AAR. We also aimed to determine...... (14.7 ± 5.6 vs. 8.7 ± 5.1 ms, P = 0.02). CONCLUSIONS: T2 relaxation parameters are different in the infarcted and salvaged myocardium, and both are significantly longer than remote. Furthermore, the magnitude of increase in T2 was less in the salvaged myocardium after longer reperfusion, indicating...

Direct dating of human fossils.

Science.gov (United States)

Grün, Rainer

2006-01-01

The methods that can be used for the direct dating of human remains comprise of radiocarbon, U-series, electron spin resonance (ESR), and amino acid racemization (AAR). This review gives an introduction to these methods in the context of dating human bones and teeth. Recent advances in ultrafiltration techniques have expanded the dating range of radiocarbon. It now seems feasible to reliably date bones up to 55,000 years. New developments in laser ablation mass spectrometry permit the in situ analysis of U-series isotopes, thus providing a rapid and virtually non-destructive dating method back to about 300,000 years. This is of particular importance when used in conjunction with non-destructive ESR analysis. New approaches in AAR analysis may lead to a renaissance of this method. The potential and present limitations of these direct dating techniques are discussed for sites relevant to the reconstruction of modern human evolution, including Florisbad, Border Cave, Tabun, Skhul, Qafzeh, Vindija, Banyoles, and Lake Mungo. (c) 2006 Wiley-Liss, Inc.

Indicação da anuscopia de alta resolução e citologia anal na prevenção de HPV e câncer colorretal em pacientes portadores de HIV Indication of high resolution anoscopy and anal cytology for prevention of HPV and colorectal cancer in HIV patients

Directory of Open Access Journals (Sweden)

Hugo Leonardo Madeiro Arcanjo Silva

2010-12-01

Full Text Available OBJETIVO: Rastreamento do papilomavírus humano (HPV assim como sua correlação com a neoplasia anorretal nos pacientes portadores do vírus da imunodeficiência humana (HIV por meio da anuscopia de alta resolução (AAR e da citologia anal. MÉTODOS: Desenvolvemos um estudo observacional, transversal e duplo-cego em que participaram 31 pacientes portadores do HIV independente de queixas proctológicas. Os pacientes foram submetidos à AAR e citologia anal cujas lâminas foram enviadas ao setor de anatomia patológica para coloração e posterior análise. RESULTADOS: Verificamos 22 pacientes do sexo masculino e 9 do sexo feminino entre 20 e 67 anos. Dos 31 analisados, quatro encontravam-se em estágio de imunodepressão, 23 utilizavam terapia antirretroviral, 16 com passado de sexo anal receptivo e 12 com passado de condiloma acuminado. À AAR 11 pacientes tinham alterações e 7 foram confirmados pela citologia. Verificamos ainda oito pacientes com alterações à citologia os quais possuíam ausência de alterações à AAR. À citologia apresentaram três células escamosas atípicas de significância (Ascus, do inglês atypical squamous cells of undetermined significance, cinco com paraceratose e/ou hiperceratose, seis lesões intraepiteliais de baixo grau e uma lesão intraepitelial de alto grau. CONCLUSÃO: Sugerimos a utilização da AAR aliada à citologia anal para rastreamento nos pacientes portadores do HIV, visto que esses exames complementam-se para a detecção de lesões que estejam relacionadas ao câncer anorretal.OBJECTIVE: Screening for HPV as well as its correlation with anorectal cancer in patients carrying the human immuno deficiency virus (HIV through high-resolution anoscopy (HRA and anal cytology. METHODS: We developed an observational study, double-blind attended by 31 patients with HIV independent proctologic complaints. Patients underwent HRA and anal cytology slides were sent to which sector pathology staining and

Novel Synergistic Therapy for Metastatic Breast Cancer: Magnetic Nanoparticle Hyperthermia of the Neovasculature Enhanced by a Vascular Disruption Agent

Science.gov (United States)

2013-04-01

bovine serum and antibiotics (VEC Technologies) on gelatin coated surface. SK- 0V-3 ovarian adenocarcinoma cell line was cultured at 37° C under a...are formed from mouse cells. Unlike xenograft models, which require an immunocompromised mouse to avoid rejection of the tumor, the PyMT mouse

Toward a Unified Military Response: Hurricane Sandy and the Dual Status Commander

Science.gov (United States)

2015-04-01

18th tropical depression of the season formed over the southwestern Caribbean Sea and quickly strength- ened into Tropical Storm Sandy late that... Centennial , a combined Title 10 and 32 operation, during the Sep- tember 2013 response to the Colorado Floods. 117 APPENDIX I ACRONYMS AAR After Action

Raadioteatri looming juubelieelsel aastal / Madis Kolk

Index Scriptorium Estoniae

Kolk, Madis, 1974-

2008-01-01

Raadioteatris 2007. aastal välja tulnud kuuest uuest kuuldemängust: Roland Schimmelpfennigi "Araabia öö", Aleksander Alleni "Elu sees", Aare Toikka viieosaline järjelugu "Kroonu", Mart Kivastiku "Nokia", Eva Östergreni "Tüdrukud", Üllar ja Rünno Saaremäe viieosaline lastelugu "Käpipuu vennaskond"

78 FR 7857 - Proposed Agency Information Collection Activities; Comment Request

Science.gov (United States)

2013-02-04

... below have been forwarded to the Office of Management and Budget (OMB) for review and comment. The ICRs... brand identification of the material. (3) Each individual unit of a glazing material that has...) the manufacturer of the material; (iii) the type or brand identification of the material. AAR believes...

Unit 1A: General Approach to the Teaching of Architecture

DEFF Research Database (Denmark)

Gammelgaard Nielsen, Anders

2011-01-01

An ideal course Ever since the founding of the Aar- hus School of Architecture in 1965 there has been a tradition for lively discussion surrounding the content of the architecture program. The discussion has often been con- ducted from ideological or norma- tive positions, with the tendency to st...

Proteomic-coupled-network analysis of T877A-androgen receptor interactomes can predict clinical prostate cancer outcomes between White (non-Hispanic and African-American groups.

Directory of Open Access Journals (Sweden)

Naif Zaman

Full Text Available The androgen receptor (AR remains an important contributor to the neoplastic evolution of prostate cancer (CaP. CaP progression is linked to several somatic AR mutational changes that endow upon the AR dramatic gain-of-function properties. One of the most common somatic mutations identified is Thr877-to-Ala (T877A, located in the ligand-binding domain, that results in a receptor capable of promiscuous binding and activation by a variety of steroid hormones and ligands including estrogens, progestins, glucocorticoids, and several anti-androgens. In an attempt to further define somatic mutated AR gain-of-function properties, as a consequence of its promiscuous ligand binding, we undertook a proteomic/network analysis approach to characterize the protein interactome of the mutant T877A-AR in LNCaP cells under eight different ligand-specific treatments (dihydrotestosterone, mibolerone, R1881, testosterone, estradiol, progesterone, dexamethasone, and cyproterone acetate. In extending the analysis of our multi-ligand complexes of the mutant T877A-AR we observed significant enrichment of specific complexes between normal and primary prostatic tumors, which were furthermore correlated with known clinical outcomes. Further analysis of certain mutant T877A-AR complexes showed specific population preferences distinguishing primary prostatic disease between white (non-Hispanic vs. African-American males. Moreover, these cancer-related AR-protein complexes demonstrated predictive survival outcomes specific to CaP, and not for breast, lung, lymphoma or medulloblastoma cancers. Our study, by coupling data generated by our proteomics to network analysis of clinical samples, has helped to define real and novel biological pathways in complicated gain-of-function AR complex systems.

DVD. Piret Tamm soovitab : "Rütm kisub kaasa" / Piret Tamm

Index Scriptorium Estoniae

Tamm, Piret, 1966-

2007-01-01

Mängufilm "Rütm kisub kaasa" ("Take the Lead") : režissöör Liz Friedlander : peaosas Antonio Banderas : Ameerika Ühendriigid 2006. Film põhineb tantsuõpetaja Pierre Dulaine'i tantsuteraapia tegevusel

Anneli Remme soovitab : Kriguli ja Grigorjeva uued teosed / Anneli Remme

Index Scriptorium Estoniae

Remme, Anneli, 1968-

2008-01-01

Ülo Kriguli "Preces ad lucem" ("Palve valguse poole") ja Galina Grigorjeva "Nature Morte" ettekandest Eesti Filharmoonia Kammerkoori (dirigent Daniel Reuss) esituses 23. okt. Tallinnas Niguliste kirikus ja 24. okt. Pärnu Eliisabeti kirikus. Tallinna kontserdil esitusel ka Sofia Gubaidulina "Nüüd aina lumi"ja Pärnu kontserdil Frank Martini "Missa"

Anneli Remme soovitab : Kuninganna Mary elu ja surm / Anneli Remme

Index Scriptorium Estoniae

Remme, Anneli, 1968-

2002-01-01

Kontserdisarja "Hingemuusika" teist kontserti raamivad Henry Purcelli teosed, millest esimene on loodud kuninganna Mary sünnipäevaks, viimane matusetseremooniaks. Barokkansambli Corelli Consort esituses 26., 27., ja 28. apr. Viljandi, Tartu ja Tallinna kirikutes

Siim Nestor soovitab : Lühidalt kõigest (peaaegu)! / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2002-01-01

27. dets Club Hollywoodis toimuvast peost "Caffe De La Soul", 28. dets. Tartus klubis Tallinn ansambli Velikije Luki esinemisest, 27. dets peost "Sünkoop" klubis Wimbledon ja Von Krahlis toimuvast aastavahetuse peost "Super Triple Masterclash 2002"

Siim Nestor soovitab : Reel People. Selffish. Xploding Plastix / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2005-01-01

Popmuusika üritustest: briti ansambel Reel People ja ansambel Hinkus 28. apr. Rock Café's Tallinnas Jazzkaare raames, läti diskor ja produtsent Andrew Eigus (Selffish) koos eesti diskoritega 29. apr. peol Pirita jõe suudmes laeval Monica, norra duo Xpoding Plastix ja ansambel Kismabande 29. apr. Sakala keskuse suures saalis Jazzkaare raames

Siim Nestor soovitab : Muda Music + Rada7.ee / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2008-01-01

Eesti muusika suuremaks rahvusvaheliseks promomiseks ja kohalike plaatidega kauplemiseks loodud neti-keskkond Muda Music läheb üle muusikafoorumi Rada7.ee alla. Üritusest 1. veebr. Tallinnas Von Krahli baaris

Anneli Remme soovitab : Eesti Muusika Päevad 2005 / Anneli Remme

Index Scriptorium Estoniae

Remme, Anneli, 1968-

2005-01-01

Eesti Muusika Päevadest 2005: 7.-14. apr. Estonia kontserdisaalis, Viru Keskuses, Eesti Teatri- ja Muusikamuuseumis, Rahvusooperis Estonia, Õpetajate majas, Eesti Muusikaakadeemias, vanalinna tänavatel, Kinomajas, Stereo Lounge'is, Kanuti Gildi saalis, Eesti Kunstiakadeemias ja Metodisti kirikus (festivali peaheliloojaks valiti Arvo Pärt, autorikontsert tuleb Eino Tambergilt). Festivali kava: www.helilooja.ee

Maaleht soovitab : Vannad Urbid laulavad naistele. Pärnus uus muusikasalong

Index Scriptorium Estoniae

2008-01-01

Kevadkontserdist "Laulud elule, armastusele ja naistele" 10. mail Tallinnas Arigato spordiklubis (vt. www.arigato.ee). 18.mail avab agentuur Corelli Music Pärnu hotellis Victoria uue muusikasalongi Café Grand (vt. www.corelli.ee)

Siim Nestor soovitab : Mutant Disco. Azymuth. Klubis Hollywood / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2003-01-01

Mutant Disco klubis Prive 4. juulil. Brasiilia jazz-trio Azmuth klubis BonBon 5. juulil. Pidustuste sarja Hip Hop Cafe sünnipäeva tähistamisest klubis Hollywood 4. juulil, üritusest Ibiza Night 5. juulil

Anneli Remme soovitab : Armastuse ja sõja laulud / Anneli Remme

Index Scriptorium Estoniae

Remme, Anneli, 1968-

2008-01-01

Eesti Filharmoonia Kammerkoori ja Helsingi Barokkorkestri kontserdist Claudio Monteverdi loominguga 25. jaan. Rakvere Gümnaasiumis, 26. jaan. Tartu Jaani kirikus ja 27. jaan. Tallinnas Mustpeade majas, Euroraadio kontsert 29. jaan. Tallinna Metodisti kirikus

Siim Nestor soovitab : Supreme 7aastane. White Stripes / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2005-01-01

Kolmik Supreme tähistab oma 7. tegutsemisaastat 24. juunil Von Krahlis, kus toimub ka Krecki debüütalbumi "If You Live" (väljaandjaks ettevõte Umblu) esitlus. Detroidi blues-rock duo White Stripes esitleb oma uut albumit "Get Behind Me Satan" 29. juunil Tallinnas klubis Hollywood

Anneli Remme soovitab : Ajaloo ilu - Johann Sebastian Bach / Anneli Remme

Index Scriptorium Estoniae

Remme, Anneli, 1968-

2005-01-01

Agentuuri Corelli Music ja Eesti Klavessiinisõprade Tsunfti korraldatavast klavessiinikontsertide sarjast "Ajaloo ilu - Johann Sebastian Bach" (avakontserdid 17. sept. Kadrioru lossis, 18. sept. Pärnu Eliisabeti kirikus)

DVD. Alar Niineväli soovitab / Alar Niineväli

Index Scriptorium Estoniae

Niineväli, Alar

2007-01-01

Soome ja Hiina mütoloogiat ühendav 2006.a. fantaasiafilm "Igavese armastuse sõdalane - Jade Warrior" (Soome, Hiina, Hollandi ja Eesti ühistöö) : režissöör Antti-Jussi Annila : osades Tommi Eronen, Zhang Jingchu, Markku Peltola

Siim Nestor soovitab : Play. DNB parimad 2007. Mirabilia / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2008-01-01

Peoseeriast "Play" klubis Seduction (endine RIFF). Peost "DNB parimad" klubis UpUp. Plaadifirma Seksound tutvustab 25. jaan. Tartus Genialistide klubis ja 26. jaan. Tallinnas Von Krahlis kontsertidega oma viimast väljalaset - Mirabilia albumit "Log In Eye"

Study of the density of ganglion cells in the terminal bowel of rats with anorectal malformations Estudo da densidade das células ganglionares no intestino terminal de ratos portadores de anomalia anorretal

Directory of Open Access Journals (Sweden)

Maurício Macedo

2007-12-01

Full Text Available PURPOSE: To study the ganglion cells (GC in the terminal bowel of rats with ethylenethiourea (ETU induced anorectal malformations (ARM. METHODS: The animals were divided into three groups: Group A - normal fetuses from pregnant rats that were not administered ETU; Group B - fetuses without ARM born from pregnant rats that were administered ETU and Group C - fetuses with ARM born from pregnant rats that received ETU. ETU was administered on the 11th day of pregnancy at the dose of 125 mg/kg body weight by gastric gavage. The rats had cesarean section on the 21st day of gestation. The fetuses’ terminal bowel tissue was analyzed by immunohistochemistry to demonstrate ganglion cells. RESULTS: Statistically significant differences were found between groups A, B and C regarding ganglion cell densities. Group A had the highest cell density, followed by Group B and the lowest density was found in Group C. CONCLUSION: Ganglion cell densities are decreased in the terminal bowel of rats with ARM.OBJETIVO: Estudar as células ganglionares (CG no intestino terminal de ratos portadores de anomalia anorretal (AAR induzida pela etilenotiouréia (ETU. MÉTODOS: Os animais foram distribuídos em três grupos: Grupo A - fetos normais, obtidos de ratas grávidas às quais não foi administrada ETU; Grupo B - fetos não portadores de AAR obtidos de ratas grávidas às quais foi administrada ETU e Grupo C - fetos portadores de AAR obtidos de ratas grávidas às quais foi administrada ETU. A ETU foi administrada no décimo primeiro dia de gestação na dose de 125 mg/Kg, por gavagem. As ratas foram submetidas à laparotomia e histerotomia para retirada dos fetos no vigésimo primeiro dia de gestação. O intestino terminal dos fetos foi retirado e analisado por imunohistoquímica para pesquisa de CG. RESULTADOS: Foram encontradas diferenças estatisticamente significantes entre os grupos A, B e C quanto à densidade de CG. O grupo A apresentou a maior densidade

Quantification of both the area-at-risk and acute myocardial infarct size in ST-segment elevation myocardial infarction using T1-mapping.

Science.gov (United States)

Bulluck, Heerajnarain; Hammond-Haley, Matthew; Fontana, Marianna; Knight, Daniel S; Sirker, Alex; Herrey, Anna S; Manisty, Charlotte; Kellman, Peter; Moon, James C; Hausenloy, Derek J

2017-08-01

A comprehensive cardiovascular magnetic resonance (CMR) in reperfused ST-segment myocardial infarction (STEMI) patients can be challenging to perform and can be time-consuming. We aimed to investigate whether native T1-mapping can accurately delineate the edema-based area-at-risk (AAR) and post-contrast T1-mapping and synthetic late gadolinium (LGE) images can quantify MI size at 1.5 T. Conventional LGE imaging and T2-mapping could then be omitted, thereby shortening the scan duration. Twenty-eight STEMI patients underwent a CMR scan at 1.5 T, 3 ± 1 days following primary percutaneous coronary intervention. The AAR was quantified using both native T1 and T2-mapping. MI size was quantified using conventional LGE, post-contrast T1-mapping and synthetic magnitude-reconstructed inversion recovery (MagIR) LGE and synthetic phase-sensitive inversion recovery (PSIR) LGE, derived from the post-contrast T1 maps. Native T1-mapping performed as well as T2-mapping in delineating the AAR (41.6 ± 11.9% of the left ventricle [% LV] versus 41.7 ± 12.2% LV, P = 0.72; R 2 0.97; ICC 0.986 (0.969-0.993); bias -0.1 ± 4.2% LV). There were excellent correlation and inter-method agreement with no bias, between MI size by conventional LGE, synthetic MagIR LGE (bias 0.2 ± 2.2%LV, P = 0.35), synthetic PSIR LGE (bias 0.4 ± 2.2% LV, P = 0.060) and post-contrast T1-mapping (bias 0.3 ± 1.8% LV, P = 0.10). The mean scan duration was 58 ± 4 min. Not performing T2 mapping (6 ± 1 min) and conventional LGE (10 ± 1 min) would shorten the CMR study by 15-20 min. T1-mapping can accurately quantify both the edema-based AAR (using native T1 maps) and acute MI size (using post-contrast T1 maps) in STEMI patients without major cardiovascular risk factors. This approach would shorten the duration of a comprehensive CMR study without significantly compromising on data acquisition and would obviate the need to perform T2 maps and LGE imaging.

49 CFR 232.603 - Design, interoperability, and configuration management requirements.

Science.gov (United States)

2010-10-01

... Specification,” Version 2.0 (Adopted: 1999; Revised: 2002); (4) AAR S-4230, “Intratrain Communication (ITC) Specification for Cable-Based Freight Train Control System,” Version 3.0 (Adopted: 1999; Revised: 2002, 2004..., “Performance Requirements for ITC Controlled Cable-Based Distributed Power Systems,” Version 2.0 (Adopted: 2003...

78 FR 48765 - Petition for Waiver of Compliance

Science.gov (United States)

2013-08-09

... Canada who participate as non-voting members. The Task Force drafted a base safety appliance standard for... that the AAR standard provides an equal or greater level of safety in each instance. In addition, the... parties are invited to participate in these proceedings by submitting written views, data, or comments...

49 CFR 179.4 - Changes in specifications for tank cars.

Science.gov (United States)

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Changes in specifications for tank cars. 179.4... TANK CARS Introduction, Approvals and Reports § 179.4 Changes in specifications for tank cars. (a...—Tank Car Safety, AAR, for consideration by its Tank Car Committee. An application for construction of...

Pink läks pikemaks... / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2007-01-01

20. sept. VAT Teatris esietendunud Eesti Muusika ja Teatriakadeemia Lavakunstikooli lavastajate õppesuuna tudengite koolitööst "Pink", mis koosneb kahest iseseisvast loost - Jon Fosse "Talv", lavastaja Robert Annus ja Edward Albee "Loomaaialugu", lavastaja Uku Uusberg. Lisaks küsimus "Aare Toikka, kuidas noored lavastajatudengid VAT Teatri tiiva alla sattusid?"

76 FR 43662 - 36(b)(1) Arms Sales Notification

Science.gov (United States)

2011-07-21

... DEPARTMENT OF DEFENSE Office of the Secretary [Transmittal Nos. 11-15] 36(b)(1) Arms Sales... Department of Defense is publishing the unclassified text of a section 36(b)(1) arms sales notification. This...) Military Department: Navy (AAR) (v) Prior Related Cases, if any: None (vi) Sales Commission, Fee, etc...

Eesti võimalused Soome lahe kasvukolmnurgas / Aare-Maldus Uustalu

Index Scriptorium Estoniae

Uustalu, Aare-Maldus, 1935-

2005-01-01

Euroopa Komisjoni ekspert logistika, transpordi ja regionaalökonoomika alal, TTÜ Tallinna Kolledzhi dotsent 2002. aasta alguses käivitatud Soome lahe kasvukolmnurga projektist, Eesti majanduse arenguperspektiivist projekti raames ning Eesti riigiametnike ükskõiksusest projekti suhtes. Via Baltica lisakoridoride projekti Via Islands ideest

The energy situation in year 2050; Energilaeget aar 2050

Energy Technology Data Exchange (ETDEWEB)

Azar, C.; Lindgren, K.; Hijino, E. [Chalmers Univ. of Technology, Goeteborg (Sweden). Dept. of Physical Resource Theory

1998-07-01

This study outlines the Swedish energy system for the case where international agreements have been reached to stabilize the atmospheric CO2 levels at 400-500 ppm. Energy scenarios for Sweden in 2050 examine the possibility to reduce emissions of CO2, phase-out nuclear power and still maintain high growth for the standard of living. In a `post-materialistic` scenario, a CO2 reduction of 75% is used, while the two `materialistic` scenarios use a reduction of 75% or 50%. In the materialistic scenarios, activities grow by 50%-100% in most sectors (markedly higher for some sectors, e.g. transportation). The post-materialistic scenarios has a lower growth. According to the authors, there exists no insurmountable technical or economic problems to realize these scenarios. Higher energy efficiency, increased use of renewable energy sources (in particular biofuels) and a modest use of natural gas will be sufficient for the energy supplies needed - about 5-20 % lower than 1995 100 refs, 24 figs, 11 tabs

Industrial trigeneration using ammonia-water absorption refrigeration systems (AAR)

International Nuclear Information System (INIS)

Colonna, Piero; Gabrielli, Sandro

2003-01-01

In many industrial processes there is a simultaneous need for electric power and refrigeration at low temperatures. Examples are in the food and chemical industries. Nowadays the increase in fuel prices and the ecological implications are giving an impulse to energy technologies that better exploit the primary energy source and integrated production of utilities should be considered when designing a new production plant. The number of so-called trigeneration systems installations (electric generator and absorption refrigeration plant) is increasing. If low temperature refrigeration is needed (from 0 to -40 deg. C), ammonia-water absorption refrigeration plants can be coupled to internal combustion engines or turbogenerators. A thermodynamic system study of trigeneration configurations using a commercial software integrated with specifically designed modules is presented. The study analyzes and compares heat recovery from the primary mover at different temperature levels. In the last section a simplified economic assessment that takes into account disparate prices in European countries compares conventional electric energy supply from the grid and optimized trigeneration plants in one test case (10 MW electric power, 7000 h/year)

78 FR 78508 - Quarterly Rail Cost Adjustment Factor

Science.gov (United States)

2013-12-26

... (ICC) outlined the procedures for calculating the all-inclusive index of railroad input prices [[Page... Association of American Railroads (AAR) is required to calculate the index on a quarterly basis and submit it... Procedures--Productivity Adjustment, 5 I.C.C.2d 434 (1989), aff'd sub nom. Edison Electric Institute v. ICC...

Gallup : kirjandus, kirjanik, kriitika ja kriitik : [küsitlus

Index Scriptorium Estoniae

2005-01-01

Küsimustele vastavad: Jan Kaus, Arne Merilai, Aarne Ruben, Peeter Sauter, Asta Põldmäe, Aare Pilv, Arvo Valton, Lauri Sommer, Mari Laaniste, Toomas Raudam, Ivar Sild, Olev Remsu, Kalle Kurg, Fagira D Morti, Eeva Park, Neeme Lopp, Valle-Sten Maiste, Sirli Ojaste, Ene-Reet Soovik, Märt Väljataga, Indrek Mesikepp

Igavene eksport : [luuletused] / Kauksi Ülle

Index Scriptorium Estoniae

Kauksi Ülle, pseud., 1962-

2005-01-01

Sisu: Igavene eksport / võru keelest eesti keelde tõlkinud Aare Pilv ; "Sinno uika ma..." ; "Piaq vasta..." / võru keelest udmurdi keelde tõlkinud Irina Orehhova, Svetlana Ljubimova ; Paat ; Jummalhoitku / võru keelest udmurdi keelde tõlkinud Irina Orehhova, Pjotr Zahharov ; Säitsme vele sõsar / udmurdi keelde tõlkinud Pjotr Zahharov

Kas läheb ka Ruudi tapmiseks? / Kati Murutar

Index Scriptorium Estoniae

Murutar, Kati, 1967-

2006-01-01

Lastefilm "Ruudi" : stsenaristid Katrin Laur, Aare Toikka, Aarne Mägi : režissöör Katrin Laur : nimiosas lapsnäitleja Paul Oskar Soe : Allfilm - MRP Matila Röhr Productions - Schmidtz Katze Filmkollektiv 2006. Võetud kõne alla ka Peeter Simmi "Kõrini!" ja Peeter Urbla "Stiilipeo" arvustaja meelest teenimatult mahategevad retsensioonid

Raamat / Matis Rodin

Index Scriptorium Estoniae

Rodin, Matis

2012-01-01

Tutvustus: Kalm, Mart. Rannalinn, seenrõdu ja viinakapp : Pärnu linnaarhitekt Olev Siinmaa. Eesti Arhitektuurimuuseum : Eesti Kunstiakadeemia, 2012; Olander, Aare. Kadunud vaated : Tallinna muutumine enam kui 400 fotol. Tänapäev, 2012; Mälestiste restaureerimine : enne ja pärast 2005-2011 / koostanud Britta Lainevool ja Ülo Puustak. Muinsuskaitseamet, 2011

NCBI nr-aa BLAST: CBRC-CFAM-23-0010 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-CFAM-23-0010 sp|Q6TCG2|PAQR9_MOUSE Progestin and adipoQ receptor family member 9 (Progesti...n and adipoQ receptor family member IX) gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 0.0 91% ...

NCBI nr-aa BLAST: CBRC-BTAU-01-3057 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-BTAU-01-3057 sp|Q6TCG2|PAQR9_MOUSE Progestin and adipoQ receptor family member 9 (Progesti...n and adipoQ receptor family member IX) gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 0.0 90% ...

Treatment with the C5a receptor antagonist ADC-1004 reduces myocardial infarction in a porcine ischemia-reperfusion model

Directory of Open Access Journals (Sweden)

Arheden Håkan

2010-09-01

Full Text Available Abstract Background Polymorphonuclear neutrophils, stimulated by the activated complement factor C5a, have been implicated in cardiac ischemia/reperfusion injury. ADC-1004 is a competitive C5a receptor antagonist that has been shown to inhibit complement related neutrophil activation. ADC-1004 shields the neutrophils from C5a activation before they enter the reperfused area, which could be a mechanistic advantage compared to previous C5a directed reperfusion therapies. We investigated if treatment with ADC-1004, according to a clinically applicable protocol, would reduce infarct size and microvascular obstruction in a large animal myocardial infarct model. Methods In anesthetized pigs (42-53 kg, a percutaneous coronary intervention balloon was inflated in the left anterior descending artery for 40 minutes, followed by 4 hours of reperfusion. Twenty minutes after balloon inflation the pigs were randomized to an intravenous bolus administration of ADC-1004 (175 mg, n = 8 or saline (9 mg/ml, n = 8. Area at risk (AAR was evaluated by ex vivo SPECT. Infarct size and microvascular obstruction were evaluated by ex vivo MRI. The observers were blinded to the treatment at randomization and analysis. Results ADC-1004 treatment reduced infarct size by 21% (ADC-1004: 58.3 ± 3.4 vs control: 74.1 ± 2.9%AAR, p = 0.007. Microvascular obstruction was similar between the groups (ADC-1004: 2.2 ± 1.2 vs control: 5.3 ± 2.5%AAR, p = 0.23. The mean plasma concentration of ADC-1004 was 83 ± 8 nM at sacrifice. There were no significant differences between the groups with respect to heart rate, mean arterial pressure, cardiac output and blood-gas data. Conclusions ADC-1004 treatment reduces myocardial ischemia-reperfusion injury and represents a novel treatment strategy of myocardial infarct with potential clinical applicability.

Buyid Silk and the Tale of Bibi Shahrbanu: Identification of Biomarkers of Artificial Aging (Forgery) of Silk.

Science.gov (United States)

Moini, Mehdi; Rollman, Christopher M

2017-10-03

Buyid silk forgery is one of the most famous silk forgeries in the world. In 1924-1925, excavation of the Bibi Shahrbanu site in Iran unearthed several silk textiles. The silks were thought to be of the Buyid period (934-1062 BCE) of the Persian Empire and have since been known as the "Buyid silks". In the 1930s, more silk appeared and was reported as being from the Buyid period as well. Controversy over the authenticity of these silks escalated after the purchase of the silks by museums throughout the world. Extensive investigations of several of these silks have been conducted over the years with respect to iconography, weaving patterns, dyes/mordant, style, and even radiocarbon dating. It was found that most of the silks are not from Buyid period. To test the authenticity of these silk fabrics, the recently developed silk dating technique using amino acid racemization (AAR) in conjunction with capillary electrophoresis mass spectrometry was applied to 13 Buyid silk specimens from the Textile Museum collections. Among these silk specimens, the AAR ratios of only one specimen were consistent with authentic silk fabrics collected from various museums. In addition, the aspartic acid racemization ratio of this specimen was also consistent with its 14 C dating. The other "Buyid silks" showed excessive levels of amino acid racemization not only for aspartic acid, but also for phenylalanine and tyrosine, inconsistent with racemization rates of these amino acids in authentic historical silk fabrics. Treatment of modern silk with a base at different pH and temperature reproduced the AAR pattern of the Buyid silks, implying that chemical treatment with a base at relatively high temperatures was perhaps the method used to artificially age these fabrics. The results imply that the racemization ratios of aspartic acid, phenylalanine, and tyrosine can be used as biomarkers for identification of naturally versus artificially aged silk.

Alkane Biosynthesis Genes in Cyanobacteria and Their Transcriptional Organization

International Nuclear Information System (INIS)

Klähn, Stephan; Baumgartner, Desirée; Pfreundt, Ulrike; Voigt, Karsten; Schön, Verena; Steglich, Claudia; Hess, Wolfgang R.

2014-01-01

In cyanobacteria, alkanes are synthesized from a fatty acyl-ACP by two enzymes, acyl–acyl carrier protein reductase and aldehyde deformylating oxygenase. Despite the great interest in the exploitation for biofuel production, nothing is known about the transcriptional organization of their genes or the physiological function of alkane synthesis. The comparison of 115 microarray datasets indicates the relatively constitutive expression of aar and ado genes. The analysis of 181 available genomes showed that in 90% of the genomes both genes are present, likely indicating their physiological relevance. In 61% of them they cluster together with genes encoding acetyl-CoA carboxyl transferase and a short-chain dehydrogenase, strengthening the link to fatty acid metabolism and in 76% of the genomes they are located in tandem, suggesting constraints on the gene arrangement. However, contrary to the expectations for an operon, we found in Synechocystis sp. PCC 6803 specific promoters for the two genes, sll0208 (ado) and sll0209 (aar), which give rise to monocistronic transcripts. Moreover, the upstream located ado gene is driven by a proximal as well as a second, distal, promoter, from which a third transcript, the ~160 nt sRNA SyR9 is transcribed. Thus, the transcriptional organization of the alkane biosynthesis genes in Synechocystis sp. PCC 6803 is of substantial complexity. We verified all three promoters to function independently from each other and show a similar promoter arrangement also in the more distant Nodularia spumigena, Trichodesmium erythraeum, Anabaena sp. PCC 7120, Prochlorococcus MIT9313, and MED4. The presence of separate regulatory elements and the dominance of monocistronic mRNAs suggest the possible autonomous regulation of ado and aar. The complex transcriptional organization of the alkane synthesis gene cluster has possible metabolic implications and should be considered when manipulating the expression of these genes in cyanobacteria.

Reversible Unfolding of Rhomboid Intramembrane Proteases.

Science.gov (United States)

Panigrahi, Rashmi; Arutyunova, Elena; Panwar, Pankaj; Gimpl, Katharina; Keller, Sandro; Lemieux, M Joanne

2016-03-29

Denaturant-induced unfolding of helical membrane proteins provides insights into their mechanism of folding and domain organization, which take place in the chemically heterogeneous, anisotropic environment of a lipid membrane. Rhomboid proteases are intramembrane proteases that play key roles in various diseases. Crystal structures have revealed a compact helical bundle with a buried active site, which requires conformational changes for the cleavage of transmembrane substrates. A dimeric form of the rhomboid protease has been shown to be important for activity. In this study, we examine the mechanism of refolding for two distinct rhomboids to gain insight into their secondary structure-activity relationships. Although helicity is largely abolished in the unfolded states of both proteins, unfolding is completely reversible for HiGlpG but only partially reversible for PsAarA. Refolding of both proteins results in reassociation of the dimer, with a 90% regain of catalytic activity for HiGlpG but only a 70% regain for PsAarA. For both proteins, a broad, gradual transition from the native, folded state to the denatured, partly unfolded state was revealed with the aid of circular dichroism spectroscopy as a function of denaturant concentration, thus arguing against a classical two-state model as found for many globular soluble proteins. Thermal denaturation has irreversible destabilizing effects on both proteins, yet reveals important functional details regarding substrate accessibility to the buried active site. This concerted biophysical and functional analysis demonstrates that HiGlpG, with a simple six-transmembrane-segment organization, is more robust than PsAarA, which has seven predicted transmembrane segments, thus rendering HiGlpG amenable to in vitro studies of membrane-protein folding. Copyright © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.

[Comparison of various noninvasive serum markers of liver fibrosis in chronic viral liver disease].

Science.gov (United States)

Kim, Sun Min; Sohn, Joo Hyun; Kim, Tae Yeob; Roh, Young Wook; Eun, Chang Soo; Jeon, Yong Cheol; Han, Dong Soo; Oh, Young Ha

2009-12-01

The aim of this study was to determine the clinical performances of noninvasive serum markers for the prediction of liver fibrosis in chronic viral liver diseases. We analyzed a total of 225 patients with chronic viral liver diseases (180 with hepatitis B virus, 43 with hepatitis C virus, and 2 with hepatitis B+C virus) who underwent a liver biopsy procedure at the Hanyang University Guri Hospital between March 2002 and February 2007. Serum was also obtained at the time of liver biopsy. Liver fibrosis was staged according to the scoring system proposed by the Korean Study Group for the Pathology of Digestive Diseases. Various noninvasive serum markers were evaluated, including the aspartate aminotransferase (AST)/alanine aminotransferase (ALT) ratio (AAR), age-platelet (AP) index, AST/platelet ratio index (APRI), cirrhosis discriminant score (CDS), platelet count, hyaluronic acid (HA), and type IV collagen. There were 17, 40, 61, 74, and 33 patients at stages F0, F1, F2, F3, and F4, respectively. The overall diagnostic accuracies of each marker, as determined by the area under receiver operating characteristics curves, were APRI=0.822, CDS=0.776, platelet count=0.773, AP index=0.756, HA=0.749, type IV collagen=0.718, and AAR=0.642 for predicting significant fibrosis (> or =F2); and CDS=0.835, platelet count=0.795, AP index=0.794, HA=0.766, AAR=0.711, type IV collagen=0.697, and APRI=0.691 for predicting extensive fibrosis (> or =F3). All noninvasive serum markers evaluated in this study were useful for predicting significant or extensive liver fibrosis in chronic viral liver diseases. In particular, APRI was most useful for the prediction of significant fibrosis, and CDS was most useful for the prediction of extensive fibrosis.

Alkane Biosynthesis Genes in Cyanobacteria and Their Transcriptional Organization

Energy Technology Data Exchange (ETDEWEB)

Klähn, Stephan; Baumgartner, Desirée; Pfreundt, Ulrike; Voigt, Karsten; Schön, Verena; Steglich, Claudia; Hess, Wolfgang R., E-mail: wolfgang.hess@biologie.uni-freiburg.de [Genetics and Experimental Bioinformatics, Institute of Biology 3, Faculty of Biology, University of Freiburg, Freiburg (Germany)

2014-07-14

In cyanobacteria, alkanes are synthesized from a fatty acyl-ACP by two enzymes, acyl–acyl carrier protein reductase and aldehyde deformylating oxygenase. Despite the great interest in the exploitation for biofuel production, nothing is known about the transcriptional organization of their genes or the physiological function of alkane synthesis. The comparison of 115 microarray datasets indicates the relatively constitutive expression of aar and ado genes. The analysis of 181 available genomes showed that in 90% of the genomes both genes are present, likely indicating their physiological relevance. In 61% of them they cluster together with genes encoding acetyl-CoA carboxyl transferase and a short-chain dehydrogenase, strengthening the link to fatty acid metabolism and in 76% of the genomes they are located in tandem, suggesting constraints on the gene arrangement. However, contrary to the expectations for an operon, we found in Synechocystis sp. PCC 6803 specific promoters for the two genes, sll0208 (ado) and sll0209 (aar), which give rise to monocistronic transcripts. Moreover, the upstream located ado gene is driven by a proximal as well as a second, distal, promoter, from which a third transcript, the ~160 nt sRNA SyR9 is transcribed. Thus, the transcriptional organization of the alkane biosynthesis genes in Synechocystis sp. PCC 6803 is of substantial complexity. We verified all three promoters to function independently from each other and show a similar promoter arrangement also in the more distant Nodularia spumigena, Trichodesmium erythraeum, Anabaena sp. PCC 7120, Prochlorococcus MIT9313, and MED4. The presence of separate regulatory elements and the dominance of monocistronic mRNAs suggest the possible autonomous regulation of ado and aar. The complex transcriptional organization of the alkane synthesis gene cluster has possible metabolic implications and should be considered when manipulating the expression of these genes in cyanobacteria.

Prediction of esophageal varices and variceal hemorrhage in patients with acute upper gastrointestinal bleeding.

Science.gov (United States)

Rockey, Don C; Elliott, Alan; Lyles, Thomas

2016-03-01

In patients with upper gastrointestinal bleeding (UGIB), identifying those with esophageal variceal hemorrhage prior to endoscopy would be clinically useful. This retrospective study of a large cohort of patients with UGIB used logistic regression analyses to evaluate the platelet count, aspartate aminotransferase (AST) to platelet ratio index (APRI), AST to alanine aminotransferase (ALT) ratio (AAR) and Lok index (all non-invasive blood markers) as predictors of variceal bleeding in (1) all patients with UGIB and (2) patients with cirrhosis and UGIB. 2233 patients admitted for UGIB were identified; 1034 patients had cirrhosis (46%) and of these, 555 patients (54%) had acute UGIB due to esophageal varices. In all patients with UGIB, the platelet count (cut-off 122,000/mm(3)), APRI (cut-off 5.1), AAR (cut-off 2.8) and Lok index (cut-off 0.9) had area under the curve (AUC)s of 0.80 0.82, 0.64, and 0.80, respectively, for predicting the presence of varices prior to endoscopy. To predict varices as the culprit of bleeding, the platelet count (cut-off 69,000), APRI (cut-off 2.6), AAR (cut-off 2.5) and Lok Index (0.90) had AUCs of 0.76, 0.77, 0.57 and 0.73, respectively. Finally, in patients with cirrhosis and UGIB, logistic regression was unable to identify optimal cut-off values useful for predicting varices as the culprit bleeding lesion for any of the non-invasive markers studied. For all patients with UGIB, non-invasive markers appear to differentiate patients with varices from those without varices and to identify those with a variceal culprit lesion. However, these markers could not distinguish between a variceal culprit and other lesions in patients with cirrhosis. Copyright © 2016 American Federation for Medical Research.

Genetic variations in the α(2A)-adrenoreceptor are associated with blood pressure response to the agonist dexmedetomidine.

Science.gov (United States)

Kurnik, Daniel; Muszkat, Mordechai; Li, Chun; Sofowora, Gbenga G; Friedman, Eitan A; Scheinin, Mika; Wood, Alastair J J; Stein, C Michael

2011-04-01

α(2A)-Adrenoceptors (α(2A)-ARs) have important roles in sympathetic cardiovascular regulation. Variants of ADRA2A affect gene transcription and expression and are associated with insulin release and risk for type 2 diabetes. We examined whether ADRA2A variants are also associated with cardiovascular responses to the selective α(2)-AR-agonist dexmedetomidine. Seventy-three healthy subjects participated in a placebo-controlled, single-blind study. After 3 infusions of placebo, subjects received 3 incremental infusions of dexmedetomidine (cumulative dose, 0.4 μg/kg). Primary outcomes were changes in systolic blood pressure (SBP) and plasma norepinephrine concentrations, measured as difference of the area-under-the-curve during placebo and dexmedetomidine infusions (ΔAUC). We used multiple linear regression analysis to examine the associations between 9 ADRA2A tagging variants and 5 inferred haplotypes and ΔAUC after adjustment for covariates. Homozygous carriers of rs553668 and the corresponding haplotype 4, previously associated with increased α(2A)-AR expression, had a 2.2-fold greater decrease in AUC(SBP) after dexmedetomidine (adjusted P=0.006); similarly, the maximum decrease in SBP was 24.7±8.1 mm Hg compared with 13.6±5.9 mm Hg in carriers of the wild-type allele (P=0.007). Carriers of haplotype 3, previously associated with reduced α(2A)-AR expression, had a 44% smaller decrease in AUC(SBP) (P=0.013). Haplotype information significantly improved the model predicting the decrease in SBP (Pblood pressure and heart rate. Genotypes were not significantly associated with norepinephrine responses. Common ADRA2A variants are associated with the hypotensive response to dexmedetomidine. Effects of specific variants/haplotypes in vivo are compatible with their known effects on gene expression in vitro.

Ostetud lõputööga saaks ülikoolidiplomi kätte küll / Kristi Leppik

Index Scriptorium Estoniae

Leppik, Kristi

2008-01-01

Plagiaadist, autoriõigusest ja lõputööde ostmisest ajakirjandusliku eksperimendina korraldatud õigusteaduse bakalaureuse lõputöö hankimise näitel Kommenteerivad Tallinna Tehnikaülikooli ehitusteaduskonna dekaan Roode Liias, Akadeemia Nord õigusteaduste dekaan Aare Kruuser, Tartu Ülikooli majandusteaduskonna arenduspordekaan Jüri Sepp, Tallinna Ülikooli riigireaduste instituudi direktor Leif Kalev

Short outlines of books by Estonian authors / Janika Kronberg and Rutt Hinrikus

Index Scriptorium Estoniae

Kronberg, Janika, 1963-

2010-01-01

Arvustus: Käsper, Kalle. Buridanid. I-V. Tallinn : Eesti Keele Sihtasutus, 2005-2010 ; Kivastik, Mart. Eesti asjad. Tartu : Kaks Musketäri, 2010 ; Kangro, Maarja. Ahvid ja solidaarsus. Tallinn : Eesti keele Sihtasutus, 2010 ; Põder, Rein. Unustatud. Tallinn : Eesti Raamat, 2010 ; Kesküla, Kalev. Elu sumedusest. Tallinn : Tuum, 2009 ; Pilv, Aare. Ramadaan. Tallinn : Tuum, 2010

Tallinna Merepäevade turismikonverents

Index Scriptorium Estoniae

2012-01-01

13. juulil Lennusadama angaarides toimunud turismikonverentsist "Lennukad ideed Lennusadamas", kus esinesid Tallinna abilinnapea Taavi Aas, Tallinna Sadama ärisuunajuht Ahto Ader, müügijuht Aare Maurer, EHTE arenduse ja uuringute osakonna juhataja Ain Hinsberg, kes rääkis projektist "Cultural Tourism 2011", Tallinna Lennujaama juhatuse esimees Rein Loik, Lennusadama tegevjuht Ott Sarapuu

Miks halvustada konkurenti? / Timo Riismaa

Index Scriptorium Estoniae

Riismaa, Timo

2006-01-01

Konkureeriva ettevõtte toodete halvustamisest. ThermiSol OÜ ja Saint Gobain Isover Eesti AS-i vahelisest kohtuasjast. Vt. ka: Kas Eesti tootjad halvustavad üksteise tooteid? Küsimusele vastavad Reiden Plaat AS-i müügijuht Aldo Unga, OÜ V-Temps juhataja Aare Võsu ja Saint-Gobain Isover Eesti AS-i marketingijuht Hellart Kala

David Lynchi lamella / Slavoj Žižek ; tõlkinud Hasso Krull

Index Scriptorium Estoniae

Žižek, Slavoj, 1949-

1996-01-01

Režissöör ja tema filmide psühhoanalüütiline analüüs, tõlge kogumikust "Reading Seminar XI. Lacan's Four Fundamental Concepts of Psychoanalysis", 1995. Lisad : tõlkija seletab sõna "lamella" tähenduse, Aare Ermeli koostatud režissööri filmograafia (mittetäielik)

Peamise Oscari näppas "Kokkupõrge" / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2006-01-01

Kuidas ja miks juhtus, et 78. Ameerika Filmiakadeemia Oscari-tseremoonial kuulutati parimaks filmiks Paul Haggise "Kokkupõrge" ("Crash") seni üldiselt favoriidiks peetud Ang Lee "Brokebacki mäe" ("Brokeback Mountain") asemel. Lisatud arvamused, mille autoriteks Aare Tilk ja Ilmar Raag ning Timo Dieneri vastus küsimusele "Kas "Kokkupõrge" jõuab ka Eestisse?"

NCBI nr-aa BLAST: CBRC-GACU-23-0054 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-GACU-23-0054 sp|Q6TCG2|PAQR9_MOUSE Progestin and adipoQ receptor family member 9 (Progesti...n and adipoQ receptor family member IX) gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 4e-55 36% ...

NCBI nr-aa BLAST: CBRC-XTRO-01-3489 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-XTRO-01-3489 sp|Q6TCG2|PAQR9_MOUSE Progestin and adipoQ receptor family member 9 (Progesti...n and adipoQ receptor family member IX) gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 1e-151 78% ...

NCBI nr-aa BLAST: CBRC-PMAR-01-0530 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-PMAR-01-0530 sp|Q6TCG2|PAQR9_MOUSE Progestin and adipoQ receptor family member 9 (Progesti...n and adipoQ receptor family member IX) gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 6e-69 42% ...

NCBI nr-aa BLAST: CBRC-OLAT-26-0036 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-OLAT-26-0036 sp|Q6TCG2|PAQR9_MOUSE Progestin and adipoQ receptor family member 9 (Progesti...n and adipoQ receptor family member IX) gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 1e-55 36% ...

NCBI nr-aa BLAST: CBRC-DRER-07-0075 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-DRER-07-0075 sp|Q6TCG2|PAQR9_MOUSE Progestin and adipoQ receptor family member 9 (Progesti...n and adipoQ receptor family member IX) gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 9e-57 36% ...

A guidance law for UAV autonomous aerial refueling based on the iterative computation method

Directory of Open Access Journals (Sweden)

Luo Delin

2014-08-01

Full Text Available The rendezvous and formation problem is a significant part for the unmanned aerial vehicle (UAV autonomous aerial refueling (AAR technique. It can be divided into two major phases: the long-range guidance phase and the formation phase. In this paper, an iterative computation guidance law (ICGL is proposed to compute a series of state variables to get the solution of a control variable for a UAV conducting rendezvous with a tanker in AAR. The proposed method can make the control variable converge to zero when the tanker and the UAV receiver come to a formation flight eventually. For the long-range guidance phase, the ICGL divides it into two sub-phases: the correction sub-phase and the guidance sub-phase. The two sub-phases share the same iterative process. As for the formation phase, a velocity coordinate system is created by which control accelerations are designed to make the speed of the UAV consistent with that of the tanker. The simulation results demonstrate that the proposed ICGL is effective and robust against wind disturbance.

Proteomic analysis of human norepinephrine transporter complexes reveals associations with protein phosphatase 2A anchoring subunit and 14-3-3 proteins

International Nuclear Information System (INIS)

Sung, Uhna; Jennings, Jennifer L.; Link, Andrew J.; Blakely, Randy D.

2005-01-01

The norepinephrine transporter (NET) terminates noradrenergic signals by clearing released NE at synapses. NET regulation by receptors and intracellular signaling pathways is supported by a growing list of associated proteins including syntaxin1A, protein phosphatase 2A (PP2A) catalytic subunit (PP2A-C), PICK1, and Hic-5. In the present study, we sought evidence for additional partnerships by mass spectrometry-based analysis of proteins co-immunoprecipitated with human NET (hNET) stably expressed in a mouse noradrenergic neuroblastoma cell line. Our initial proteomic analyses reveal multiple peptides derived from hNET, peptides arising from the mouse PP2A anchoring subunit (PP2A-Ar) and peptides derived from 14-3-3 proteins. We verified physical association of NET with PP2A-Ar via co-immunoprecipitation studies using mouse vas deferens extracts and with 14-3-3 via a fusion pull-down approach, implicating specifically the hNET NH 2 -terminus for interactions. The transporter complexes described likely support mechanisms regulating transporter activity, localization, and trafficking

Cardiorespiratory responses and reduced apneic time to cold-water face immersion after high intensity exercise.

Science.gov (United States)

Konstantinidou, Sylvia; Soultanakis, Helen

2016-01-01

Apnea after exercise may evoke a neurally mediated conflict that may affect apneic time and create a cardiovascular strain. The physiological responses, induced by apnea with face immersion in cold water (10 °C), after a 3-min exercise bout, at 85% of VO2max,were examined in 10 swimmers. A pre-selected 40-s apnea, completed after rest (AAR), could not be met after exercise (AAE), and was terminated with an agonal gasp reflex, and a reduction of apneic time, by 75%. Bradycardia was evident with immersion after both, 40-s of AAR and after AAE (P<0.05). The dramatic elevation of, systolic pressure and pulse pressure, after AAE, were indicative of cardiovascular stress. Blood pressure after exercise without apnea was not equally elevated. The activation of neurally opposing functions as those elicited by the diving reflex after high intensity exercise may create an autonomic conflict possibly related to oxygen-conserving reflexes stimulated by the trigeminal nerve, and those elicited by exercise. Copyright © 2015. Published by Elsevier B.V.

Exact docking flight controller for autonomous aerial refueling with back-stepping based high order sliding mode

Science.gov (United States)

Su, Zikang; Wang, Honglun; Li, Na; Yu, Yue; Wu, Jianfa

2018-02-01

Autonomous aerial refueling (AAR) exact docking control has always been an intractable problem due to the strong nonlinearity, the tight coupling of the 6 DOF aircraft model and the complex disturbances of the multiple environment flows. In this paper, the strongly coupled nonlinear 6 DOF model of the receiver aircraft which considers the multiple flow disturbances is established in the affine nonlinear form to facilitate the nonlinear controller design. The items reflecting the influence of the unknown flow disturbances in the receiver dynamics are taken as the components of the "lumped disturbances" together with the items which have no linear correlation with the virtual control variables. These unmeasurable lumped disturbances are estimated and compensated by a specially designed high order sliding mode observer (HOSMO) with excellent estimation property. With the compensation of the estimated lumped disturbances, a back-stepping high order sliding mode based exact docking flight controller is proposed for AAR in the presence of multiple flow disturbances. Extensive simulation results demonstrate the feasibility and superiority of the proposed docking controller.

Early Gadolinium Enhancement for Determination of Area at Risk

DEFF Research Database (Denmark)

Hammer-Hansen, Sophia; Leung, Steve W; Hsu, Li-Yueh

2017-01-01

OBJECTIVES: The aim of this study was to determine whether early gadolinium enhancement (EGE) by cardiac magnetic resonance (CMR) in a canine model of reperfused myocardial infarction depicts the area at risk (AAR) as determined by microsphere blood flow analysis. BACKGROUND: It remains controver......OBJECTIVES: The aim of this study was to determine whether early gadolinium enhancement (EGE) by cardiac magnetic resonance (CMR) in a canine model of reperfused myocardial infarction depicts the area at risk (AAR) as determined by microsphere blood flow analysis. BACKGROUND: It remains...... requires pathological validation. METHODS: Eleven dogs underwent 2 h of coronary artery occlusion and 48 h of reperfusion before imaging at 1.5-T. EGE imaging was performed 3 min after contrast administration with coverage of the entire left ventricle. Late gadolinium enhancement imaging was performed...... on native T1 and T2 maps. The size of EGE was significantly greater than the infarct by triphenyltetrazolium chloride (44.1 ± 15.8% vs. 20.7 ± 14.4%; p gadolinium enhancement (44.1 ± 15.8% vs. 23.5 ± 12.7%; p

Problem-Based Learning: Instructor Characteristics, Competencies, and Professional Development

Science.gov (United States)

2011-01-01

instructional segment addresses multiple competencies in a situated, naturalistic context via a sequence of classroom observation , after action review, follow...Exercise 1. Classroom observation 2. AAR 3. Direct instruction 4. Deliberate Practice 5. Field Experience 29 Table 1. Notional lesson plan for PBL...Direct Instruction, Knowledge Games 2 Reading Students - Monitor & Intervene - Facilitate Collaboration Classroom Observation #1, After Action

78 FR 59093 - Quarterly Rail Cost Adjustment Factor

Science.gov (United States)

2013-09-25

... (ICC) outlined the procedures for calculating the all-inclusive index of railroad input prices and the... American Railroads (AAR) is required to calculate the index on a quarterly basis and submit it to the...--Productivity Adjustment, 5 I.C.C. 2d 434 (1989), aff'd sub nom. Edison Electric Institute v. ICC, 969 F.2d 1221...

Paraadile annavad sära sõjaväeorkestrid. Kultuuri ja uunikumi / Andris Tammela

Index Scriptorium Estoniae

Tammela, Andris

2005-01-01

Võidupüha üritustest Paides 23. juunil. Suure-Jaani muusikapäevadest: Mati Palmi ja Aare-Paul Lattiku kontsert 22. juun. Suure-Jaani jahimajas, Sven Grünbergi, Lilian Langsepa ja Vambola Kriguli kontsert 22. juun. Suure-Jaani kirikus, Urmas Sisaski autoriõhtu 23. juun. Suure-Jaani kirikus, Jassi Zahharovi kontsert 23. juun. Soomaal Hüpassaares

Scenario Selection and Student Assessment Modules for CyberCIEGE

National Research Council Canada - National Science Library

Leng, Tiat

2003-01-01

.... In addition by tapping the CyberCIEGE event log files generated at the end of each game, we can reconstruct the game progress to support After Action Reviews (AAR) to assist the instructor and student to analyze game decisions and the student's progress. This provides a constructive follow-up to review and reinforce the concepts being taught.

Ettevõtjatel puudub logistikast terviknägemus : parim ladu on veoauto kast / Reigo Kuivjõgi

Index Scriptorium Estoniae

Kuivjõgi, Reigo

2000-01-01

Kuna ettevõtetel puudub sageli logistika terviklik koordineerimine ja kulude analüüs, on liigsed logistikakulud firma majandustulemustele suureks koormaks. Logistikateemalisest ümarlauakohtumisest võtsid osa Tallinna Tehnikakõrgkooli prorektor Enno Lend, Tallinna Tehnikaülikooli professor Aare Uustalu, Schenker-BTL-i logistikadirektor Ain Tulvi, Schenker-BTL-i tegevdirektor Meelis Arumeel ja Eesti Kaubaliinide juhataja Tõnis Hintsov

English for lawyers / Liina Soobik ; [preface: Peep Pruks

Index Scriptorium Estoniae

Soobik, Liina, 1955-

2001-01-01

Kasutatud tekstide autorid: Peep Pruks, Merit-Ene Ilja, Ilona Nurmela, Kristi Raba, Andreas Kangur, Raul Narits, Peeter Roosma, Kalle Merusk, Maret Altnurme, Jaan Ginter, Aare Tark, Norman Aas, Lasse Lehis, Hannes Veinla, Jaan Sootak, Eerik Kergandberg, Paul Varul, Jaanus Ots, Urve Liin, Irene Kull, Merle Muda, Gaabriel Tavits, Andres Vutt, Kadri Siibak, Ellen Ridaste, Heiki Pisuke, Andrus Siibak

D IE ROOM SE LUTHER SE EN HERVORMDEB ESK OU IN ...

African Journals Online (AJOL)

Test

Oor die leerstuk van die heilige Avondmaal neem Luther 'n tussen- standpunt in tussen die Roomse Kerk en die Hervormde Kerk. W aar. Rome leer dat die brood en die wyn by die bediening van die Avond maal waarlik in die vlees en bloed van Christus verander word, sodat die Avondmaalganger waarlik die liggaam van ...

NCBI nr-aa BLAST: CBRC-MDOM-07-0106 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-MDOM-07-0106 sp|Q6TCG2|PAQR9_MOUSE RecName: Full=Progestin and adipoQ receptor... family member 9; AltName: Full=Progestin and adipoQ receptor family member IX gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 0.0 88% ...

NCBI nr-aa BLAST: CBRC-TTRU-01-1190 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-TTRU-01-1190 sp|Q6TCG2|PAQR9_MOUSE RecName: Full=Progestin and adipoQ receptor... family member 9; AltName: Full=Progestin and adipoQ receptor family member IX gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 0.0 91% ...

NCBI nr-aa BLAST: CBRC-MLUC-01-0485 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-MLUC-01-0485 sp|Q6TCG2|PAQR9_MOUSE RecName: Full=Progestin and adipoQ receptor... family member 9; AltName: Full=Progestin and adipoQ receptor family member IX gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 0.0 91% ...

NCBI nr-aa BLAST: CBRC-PVAM-01-1010 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-PVAM-01-1010 sp|Q6TCG2|PAQR9_MOUSE RecName: Full=Progestin and adipoQ receptor... family member 9; AltName: Full=Progestin and adipoQ receptor family member IX gb|AAR08386.1| progestin and adipoQ receptor family member IX [Mus musculus] Q6TCG2 0.0 90% ...

Spatial and temporal modelling of fluvial aggradation in the Hasli Valley (Swiss Alps) during the last 1300 years

Science.gov (United States)

Llorca, Jaime; Schulte, Lothar; Carvalho, Filipe

2016-04-01

The Haslital delta (upper Aare River catchment, Bernese Alps) progradated into the Lake Brienz after the retreat of the Aare Glacier (post-LGM). Present delta plain geomorphology and spatial distribution of sedimentary facies result from historical fluvial dynamics and aggradation. Over centuries, local communities have struggled to control the Aare floods and to mitigate their effects on the floodplain (by means of raising artificial levees, channelizing the course, creating an underground drainage network, constructing dams at the basin headwaters). This study focuses on the spatial and temporal evolution of sediment dynamics of the floodplain by analyzing fluvial sedimentary records . The internal variability of lithostratigraphic sequences is a key issue to understand hydrological processes in the basin under the effect of environmental and anthropogenic changes of the past. The floodplain lithostratigraphy was reconstructed by coring alongside four cross-sections; each one is composed of more than 25 shallow boreholes (2 m deep) and two long drillings (variable depth, up to 9 m). The chronostratigraphical models were obtained by AMS 14C dating, and information of paleofloods and channel migration were reconstructed from historical sources (Schulte et al., 2015). The identification of different sedimentary facies, associated with the fluvial architecture structures, provides information on variations of vertical and lateral accretion processes (Houben, 2007). The location and geometry of buried channel-levee facies (gravel and coarse sand layers) indicate a significant mobility of the riverbed of the Hasli-Aare river, following an oscillatory pattern during the last millennia. Furthermore, fine sedimentary deposits and peat layers represent the existence of stable areas where floods have a low incidence. Once the different types of deposits were identified, aggradation rates were estimated in order to determine the spatial variability of the accumulation

Possibility of using remote sensing data for glaciological calculations and monitoring

Directory of Open Access Journals (Sweden)

V. G. Konovalov

2015-01-01

Full Text Available Altitude and areal characteristics of glaciation of the Earth, as well as annual ELA and AAR values for a limited number of glaciers can be found in references [10, 15, 16, 18, 29]. According to these data, the analysis of the relations between ELA, AAR, annual mass balance of glaciers and its components was performed for use in the remote monitoring of glaciation. Appropriate sample included 45 to 66 glaciers located mainly in Eurasia, at mean weighted altitudes Zmed from 520 m to 4253 m above sea level. The existence of close and stable spatial relations AAR = f (Bn and AAR = f (ELA (see Table 1 allows, ultimately obtain local or regional estimates of glacier mass balance. In 1957, the area of the moraine on the glaciers of the Pamir was 320 km 2 , or 4.8% of the total area of glaciers in the region, and after ~ 20 years it has increased to 644 km2 or 10.7% [10]. In this paper we used photos of glaciers Medvezhiy and Bivachny in late August 2007 and 2012 from the ISS. Ground resolution is of 3–5 meters. Photos were transformed into WGS projection and tied to a topographic map 1:50 000. Altitudinal interval of moraines propagation on glaciers Medvezhiy and Bivachny in 2007–2012 was equal to, respectively: 3000–5000 and 3400–4800 m above sea level. It was revealed increase of total area of the moraine on these glaciers for the years 1975– 2007. Analysis of the content and quality of the main sources of global and regional information about modern glaciation of the Earth shows that without additional thematic processing they are not suitable for monitoring the dynamics of glaciers in the major river basins and use on a par with the existing data on precipitation, temperature, humidity, cloud cover and other climatic characteristics. Additional processing should be provided to exclude asynchronies in morphometric parameters. This will reduce errors in glaciological interpretation of satellite images and improve the quality of spatial

Erikomitee soovitab ekspeaministri hooletuse pärast kohtusse anda / Kaivo Kopli

Index Scriptorium Estoniae

Kopli, Kaivo

2010-01-01

Islandi parlamendi erikomitee otsuse kohaselt on alust süüdistada endist peaministrit Geir Haardet, endist välisministrit Ingibjorg Solrun Gisladottirit, endist rahandusministrit Arni Mathieseni ja endist majandusministrit Bjorgvin Sigurdssoni riigi langemises finants- ja majanduskriisi

Anneli Remme soovitab : David Oistrahhi festival. Koorifestival Pärnus / Anneli Remme

Index Scriptorium Estoniae

Remme, Anneli, 1968-

2002-01-01

David Oistrahhi festivalist 14. juulini Pärnu Eliisabeti kirikus, Teatris Endla, Ammende villas, Eesti Õigeusu kirikus ja Pärnu Raekojas. Festivali kunstiline juht Allar Kaasik. Pärnu koorifestivalist

Maaleht soovitab : Klassikud Mooste mõisas. Romantiline Karlova päev

Index Scriptorium Estoniae

2008-01-01

String Kvarteti kontserdist kavaga "Klassikud kammerlikult" 23. mail Mooste mõisas. Bonzo, Tõuni ja meeste vokaalansambli Võta See esinemisest 17. mail Karlova päevade raames Tartu ülikooli õpetajate seminari saalis (Salme 1a)

Jaan Klõšeiko soovitab: Jaan Tootseni film "Uus maailm"

Index Scriptorium Estoniae

2011-01-01

Režissöör Jaan Tootsen dokumentaalfilmi "Uus Maailm" (produtsent Jaak Kilmi, Kuukulgur Film, 2011) saamisloost ja filmist, mis valiti 25.-30. oktoobrini Tšehhis toimuvale Jihlava rahvusvahelisele dokumentaalfilmide festivalile

Siim Nestor soovitab : HUH : energiaöö. Bad Apples / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2006-01-01

Festivali "Hea Uus Heli" hooaja lõpetamisest 15. dets. Von Krahlis Tallinnas. Ansambli Bad Apples heliplaadi "When Colours Become Day and Night" esitlusest 19. dets. Tallinnas teatri NO99 majas Jazziklubis

Rahvakunst Marika ja Heinz Valgu kollektsioonist : Heie Treier soovitab / Heie Treier

Index Scriptorium Estoniae

Treier, Heie, 1963-

2000-01-01

12. märtsini Tarbekunstimuuseumis avatud näitusest, mille on kujundanud Heinz Valk. Soovitatakse külastada Kunstihoones Anu Juuraku näitust 'Tsoon 2', kus tegeldakse identiteedi probleemidega kõrgtehnoloogilisel tasandil.

Siim Nestor soovitab : DJ Muggs. Odessa Pop : HUHi soojendus / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2007-01-01

Üritusest "HipHop Café" 27. sept. Tallinnas Club Hollywoodis, heliplaadi "The Legend of the Mask and the Assassin" esitlusest. Üritusest "Odessa Pop" festivali "Hea Uus Heli" raames 29. sept. Tallinnas Von Krahlis

Siim Nestor soovitab : Back2Bass Helsinki. Teenage Kicks / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2002-01-01

Soome trummi-ja-bassi klubi Back2Bass 28. septembril KuKu klubis Tallinnas. 28. sept. Von Krahlis toimuvast live-üritusest Teenage Kicks, kus ansambel Claire's Birthaday esitleb ka oma uut singlit "Do You Remember"

Hollandi pank soovitab Eesti Telekomi müüa / Annika Matson

Index Scriptorium Estoniae

Matson, Annika, 1976-

2004-01-01

Hollandi investeerimispanga ING jt pankade analüütikute soovitused tehinguteks Eesti Telekomi aktsiatega. Graafik: Telekomi aktsia on ING arvates ligi neljandiku võrra ülehinnatud. Vt. samas: ING-l on üle maailma 60 miljonit klienti

Rootsi soovitab pangad maksustada / Kadri Bank ; kommenteerinud Tanel Ross, Ivari Padar

Index Scriptorium Estoniae

Bank, Kadri

2010-01-01

Rootsi rahandusminister Andres Borg tegi Euroopa Liidu liikmesriikide rahandusministritele ettepaneku järgida Rootsi eeskuju ning maksustada pangad, ettepaneku jõustumisel peaksid Eesti pangad maksma loodavasse stabiliseerimisfondi umbes 50 miljonit krooni aastas

Siim Nestor soovitab : DJ Marky. Marco Passarani. Padded Cell / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2006-01-01

Drum'n'bassi peost "Jus'Fine" 20. apr. klubis Privé Tallinnas. Technomuusikapeost "Stereo88" 20. apr. Tartus klubis Illusion ja 21. apr. Tallinnas Von Krahlis. Üritusest "Mutant Disko" 21. apr. klubis Privé

Siim Nestor soovitab : Need on meie külalised / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2004-01-01

Popmuusikaüritustest Tallinna klubides: Privé's 1. apr.,"1ÖÖ%" Von Krahlis (ekstravaganza festivali Hea Uus Ilm raames) ja "Depeche Mode Party" Hollywoodis 4. apr., "Tramm ja Buss" BonBonis 7. aprillil

Siim Nestor soovitab : Uued hip-hop teosed live'is / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2006-01-01

Põhjamaade Hirmu esikplaadi "Maailma südame põhjast" esitlustest Tallinnas ja 9. juunil Tartus klubis Illusion. TommyBoy uue heliplaadi "Suur pilt" esitlustest Tallinnas ja 9. juunil Rakvere teatrikohviku laval, Stupid F heliplaadi "Nostalgilised helid"esitlusest 9. juunil Rakvere teatrikohviku laval

Alar Niineväli soovitab : "Palun tantsima" / Alar Niineväli

Index Scriptorium Estoniae

Niineväli, Alar

2005-01-01

Komöödiafilm "Kas tantsime?" ("Shall We Dance?") : stsenarist Audrey Wells : režissöör Peter Chelsom : Ameerika Ühendriigid 2004. Film on samanimelise, ka USAs ülipopulaarse 1996.a. jaapani filmi (režissöör Masayuki Suo) remake

Siim Nestor soovitab : Ben Frost ja Alexander Robotnik Eclectical / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2007-01-01

Austraalia muusik ja helilooja Ben Frost projektiga "6 guitars" esinemas festivali Eclectica raames 6. sept. Tartu klubis Rock ja Roll ja itaalia diskor Alexander Robotnik 7. sept. klubis Trehv, esinejatest

Siim Nestor soovitab : Sports Cabaret. Ans. Flirt. DJ Krii / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2002-01-01

29. nov. Tartus Club-Tallinnas toimuvast üritusest Sports Cabaret. 4. dets. klubis BonBon projekt-ansambli Flirt (koosseisus Raul Saaremets, Andres Peets, Sten Sheripov, Leslie Laasner) kontserdist. 29. nov. Von Krahlis toimuvast hip-hop peost Check One, Two, kus esinejaks läti diskor Krii

D IE NEDERLANDSEGELOOFSBEL YDEN IS ASS IM BOL IE SEGE ...

African Journals Online (AJOL)

Test

M aar aan die ander kant, as dit vir U blyk dat ons onskuldig is, wees ons dan n steun en n toevlug teen die geweld van onse vyande. W ant helaas, genadigste Heer, as mens alleen maar kan beskuldig terwyl aan die beskuldigde elke weg en middel van verdediging ontneem word, wie sal dan regverdig bevind word? W ie.

Aasta 2007 maakonna majanduses

Index Scriptorium Estoniae

2007-01-01

Tagasivaate lõppevale aastale teevad Saare maavanema Toomas Kasemaa, tulundusühistu Mereranna põllumajandusühistu juhatuse esimees Urmas Lehtsalu, Saaremaa Laevakompanii juhatuse esimees Tõnis Rihvk, turismitalunik Jorma T. Ihalainen, turismifirma Arensburgi Reisid ja Saaremaa turismiühenduse juht Margus Mölder, Kuressaare lennujaama juhataja Mati Tang ja Saaremaa piimatööstuse direktor Andi Saagpakk. Ülevaate koostas Aare Laine

Kohalik tööstus pelgab pankade ja väliskapitali kokkumängu / Margit Aedla

Index Scriptorium Estoniae

Aedla, Margit, 1970-

2003-01-01

Tallinna Piimatööstuse juhatuse esimees Aare Annus spekuleerib võimaluse üle, mille kohaselt võidakse Eesti ühinemisel EL-iga hakata rootslaste omanduses olevate pankade kaudu mõjutama meie ettevõtete käekäiku, sest kardetakse sealsete turuliidrite positsioonide halvenemist. Eesti Ühispanga juht Ain Hanschmidt ja Hansapanga juht Indrek Neivelt välistavad sellise võimaluse

Restauratsioon / Mart Velsker

Index Scriptorium Estoniae

Velsker, Mart, 1966-

1998-01-01

Arvustus: Üheksavägine. Tartu : Erakkond, 1997.Märka, Veiko. Tühja aju korinad; Rahman, Jan. Vasõst vask; Rüütle, Indrek. Lahkumine Puhjast; Serpent, Franȯis. Ka jumal on inimene (kõik EK$i Kaasaegse Kirjanduse Keskuse väljaanded, Tartu, 1997). Vastukaja: Pilv, Aare. Vastuseks Mart Velskri 'Restauratsioonile' // Vikerkaar (1998) nr. 4-5, lk. 185-186

First results of the CLIMOD project - prospects

International Nuclear Information System (INIS)

Junod, A.

1981-01-01

The area investigated extends from the mouth of the Aar at Waldshut and Basle, and between the Black Forest and the top of the Jura range. In this area there are some nuclear powerstations with cooling towers. The CLIMOD project tries to detect changes of present conditions due to the cooling tower and by other anthropogeneous effects, at least qualitatively. (DG) [de

The IT problems / the year; Norne: Erfaringer etter ett aar

Energy Technology Data Exchange (ETDEWEB)

Staerkebye, Jon

1998-07-01

This presentation discusses the year 2000 problem as dealt with by Saga. The project ''Year 2000 in Saga Petroleum'' was formally established in December 1997. Its mandate was to identify risk areas and systems related to the date problem and to establish the necessary action to reduce or eliminate the Y2K problems. The target was (1) To be ''Year 2000 Compliant'' for the most critical systems within 1.4.1999, (2) To ensure the continuity of Saga's operational and business management affairs, (3) Priority to health, environment and safety, (4) Authorities and partners should be satisfied with the way Saga carries out the Y2K project work. Few serious problems were detected, but Y2K compliance information was more difficult to obtain than expected. Major suppliers take the problem seriously, but surprisingly many have started late.

Tegelikult keskmine pension 2007. a. ei tõusegi! / Aare Kitsing

Index Scriptorium Estoniae

Kitsing, Aare

2006-01-01

Ilmunud ka: Maaleht 2. nov. lk. 8, Harjumaa 7. nov. lk. 2, Vesti Nedeli Den za Dnjom 1. dets. lk. 14. . Eesti Pensionäride Liidu aseesimees selgitab vanaduspensioni arvestamist, mille järgi pensioni tõus 3490 kroonini puudutab vaid osa kodanikke. Pensionäride Liidu nõudmised Riigikogule ja valitsusele

Johannes Hindi abil Arnold Rüütli vastu / Aare Vets

Index Scriptorium Estoniae

Vets, Aare

2006-01-01

President Arnold Rüütli vastastest rünnakutest presidendivalimiste kampaanias, näitena Eesti Ekspressis ilmunud artikkel, mille järgi Arnold Rüütel on vastutav Johannes Hindi vangistamises. J. Hindi tegevusest silikaltsiidi tootmisel ja Desintegraatori direktorina, kriminaalasja algatamisest ja karistamisest Eesti NSV-s

Märkmeid ja viiteid Ojasoo-Semperi teatri kohta / Aare Pilv

Index Scriptorium Estoniae

Pilv, Aare, 1976-

2006-01-01

Tiit Ojasoo ja Ene-Liis Semperi NO99 teater Eesti teatripildis kui uudne nähtus. Peatutakse pikemalt lavastustel "Vahel on tunne, et elu saab otsa ja armastust polnudki", "Seitse samuraid", aga ka "Verevennad" ja Draamateatris tehtud lavastusel "Julia". Kommentaarid, lk. 20

Higi ja ehmatus. Näitlemise piiripealsusest / Sirle Põdersoo, Aare Pilv

Index Scriptorium Estoniae

Põdersoo, Sirle

2004-01-01

Nelja 2003. aastal etendunud lavastuse - "Stiil ehk Mis on maailma nimi?" Von Krahli Teatris (lav. M. Unt), "Dekameron ehk Mea culpa ..." Ugalas (lav. V. Ibrahimoglu), "Kolumats" VAT Teatris (lav. C. Römer) ning "Meister ja Margarita" Vanemuises (lav. M. Unt) - põhjal näitlejatöödest. Kasut. kirjandus lk. 143

Adaptive autoregressive identification with spectral power decomposition for studying movement-related activity in scalp EEG signals and basal ganglia local field potentials

Science.gov (United States)

Foffani, Guglielmo; Bianchi, Anna M.; Priori, Alberto; Baselli, Giuseppe

2004-09-01

We propose a method that combines adaptive autoregressive (AAR) identification and spectral power decomposition for the study of movement-related spectral changes in scalp EEG signals and basal ganglia local field potentials (LFPs). This approach introduces the concept of movement-related poles, allowing one to study not only the classical event-related desynchronizations (ERD) and synchronizations (ERS), which correspond to modulations of power, but also event-related modulations of frequency. We applied the method to analyze movement-related EEG signals and LFPs contemporarily recorded from the sensorimotor cortex, the globus pallidus internus (GPi) and the subthalamic nucleus (STN) in a patient with Parkinson's disease who underwent stereotactic neurosurgery for the implant of deep brain stimulation (DBS) electrodes. In the AAR identification we compared the whale and the exponential forgetting factors, showing that the whale forgetting provides a better disturbance rejection and it is therefore more suitable to investigate movement-related brain activity. Movement-related power modulations were consistent with previous studies. In addition, movement-related frequency modulations were observed from both scalp EEG signals and basal ganglia LFPs. The method therefore represents an effective approach to the study of movement-related brain activity.

Growth-Rate Dependent Regulation of tRNA Level and Charging in Bacillus licheniformis.

Science.gov (United States)

Ferro, Iolanda; Liebeton, Klaus; Ignatova, Zoya

2017-10-13

Cellular growth crucially depends on protein synthesis and the abundance of translational components. Among them, aminoacyl-tRNAs play a central role in biosynthesis and shape the kinetics of mRNA translation, thus influencing protein production. Here, we used microarray-based approaches to determine the charging levels and tRNA abundance of Bacillus licheniformis. We observed an interesting cross-talk among tRNA expression, charging pattern, and growth rate. For a large subset of tRNAs, we found a co-regulated and augmented expression at high growth rate. Their tRNA aminoacylation level is kept relatively constant through riboswitch-regulated expression of the cognate aminoacyl-tRNA-synthetase (AARS). We show that AARSs with putative riboswitch-controlled expression are those charging tRNAs with amino acids which disfavor cell growth when individually added to the nutrient medium. Our results suggest that the riboswitch-regulated AARS expression in B. licheniformis is a powerful mechanism not only to maintain a constant ratio of aminoacyl-tRNA independent of the growth rate but concomitantly to control the intracellular level of free amino acids. Copyright © 2017 Elsevier Ltd. All rights reserved.

Hingetoit hääste konserveeritud : 3 luulesalvestist / Jürgen Rooste

Index Scriptorium Estoniae

Rooste, Jürgen, 1979-

2004-01-01

Heliplaadid: Mikiver, Mikk ; Mätlik, Heiki. Teele selle poole, millel pole lõppu ja pole ka algust [Helisalvestis] : loometund poeetide Jaan Kaplinski ja Walt Whitmani luulest. Tallinn : Eesti Raadioteater, 2004 ; Krull, Hasso. Meeter ja Demeeter [Helisalvestis]. Tallinn : S.n., 2003 ; Ord från Estland / Kristiina Ehin, fs, Jan Kaus, Asko Künnap, Aare Pilv, Lauri Sommer, Elo Viiding. S.l. : Põhjamaade Ministrite Nõukogu, [2004

Vikergallup : eesti kirjandus 2000 : [vastused Vikerkaare küsimustele

Index Scriptorium Estoniae

2001-01-01

Aut.: Epp Annus, Andres Aule, Veiko Belials, Jan Kaus, Andrus Kivirähk, Leo Luks, Hedda Maurer, Anneli Mihkelev, Marko Mägi, Aare Pilv, Jürgen Rooste, Aarne Ruben, Mihkel Samarüütel, François Serpent, Ivar Sild, Karl Martin Sinijärv, Jaak Urmet. 2000. a. parimaks uudisraamatuks tunnistati Andrus Kivirähu "Rehepapp ehk November" ja parimaks esikraamatuks Wimbergi [Jaak Urmet] "Maaaraamat"

Post Accident Procedures for Chemicals and Propellants.

Science.gov (United States)

1982-09-01

Acoustic Emission AFB - Air Force Base AFCRL - Air Force Cambridge Research Laboratories BE - AAR Bureau of Explosives BLEVE - Boiling Liquid Expanding...rupture or a BLEVE . Second, hazardous material fires were extinguished when possible with either the use of foam or water. In some cases, the car was...First Aid Kits Breathing Apparatus Mine Safety Pittsburgh, PA Appliances ,- (MSA) 5-38 .... .°.*. ’ • .*. . ° ,*. I

Low-Torque Seal Development

Science.gov (United States)

Lattime, Scott B.; Borowski, Richard

2009-01-01

The EcoTurn Class K production prototypes have passed all AAR qualification tests and received conditional approval. The accelerated life test on the second set of seals is in progress. Due to the performance of the first set, no problems are expected.The seal has demonstrated superior performance over the HDL seal in the test lab with virtually zero torque and excellent contamination exclusion and grease retention.

VAT-teater vaatab 30 aastat tulevikku / Tiiu Laks

Index Scriptorium Estoniae

Laks, Tiiu, 1984-

2010-01-01

VAT Teater toob S. Becketti "Krappi viimase lindi" lavale ebatavalisel moel. Festivalil "Draama 2010" Tartus toimub 8. septembril esimene avalik lindistus "...viimane lint / Saare esimene lint". Kontseptsioon: Tanel Saar ja Co. Esitus: Tanel Saar ja Hanna Allsaar. Näitejuhid-konsultandid: Rait Avestik ja Aare Toikka. "Krappi viimane lint" esietendub VAT Teatri ja Tanel Saare esituses 2040. a. sügisel. Festivali "Draama 2010" kavast

NCBI nr-aa BLAST: CBRC-TNIG-01-0000 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-TNIG-01-0000 ref|NP_036871.2| adrenergic receptor, alpha 2a [Rattus norvegicus...] sp|P22909|ADA2A_RAT Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2A adrenoreceptor) (Alpha-...2AAR) (CA2-47) (Alpha-2D adrenergic receptor) gb|AAC24959.1| alpha2D adrenergic receptor [Rattus norvegicus] NP_036871.2 4e-41 37% ...

NCBI nr-aa BLAST: CBRC-MMUS-19-0098 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-MMUS-19-0098 ref|NP_036871.2| adrenergic receptor, alpha 2a [Rattus norvegicus...] sp|P22909|ADA2A_RAT Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2A adrenoreceptor) (Alpha-...2AAR) (CA2-47) (Alpha-2D adrenergic receptor) gb|AAC24959.1| alpha2D adrenergic receptor [Rattus norvegicus] NP_036871.2 0.0 97% ...

Sotsiaalselt pime ja poliitiliselt impotentne teater / Alvar Loog

Index Scriptorium Estoniae

Loog, Alvar

2006-01-01

Poliitilisest ja sotsiaalsest teatrist Eestis 2005. aasta lavastuste põhjal : Pip Upponi "Adolf" Tartu Püssirohukeldris, lavastaja Ervin Õunapuu; Merle Karusoo "Misjonärid" Rakvere Teatris; Alistair Beatoni "Õnnetunne" Ugalas, lavastaja Jaak Allik; Toomas Kalli " Viimane sent" Vana Baskini Teatris, lavastaja Eino Baskin; George Orwelli "Loomade farm" Tallinna Linnateatris, lavastaja Mart Koldits; Kai Henseli "Klammi sõda" VAT Teatris, lavastaja Aare Toikka

Selgusid kirjanduse aastapreemiate saajad / Rein Veidemann ; komment. Karl Martin Sinijärv, Viivi Luik

Index Scriptorium Estoniae

Veidemann, Rein, 1946-

2006-01-01

Eesti Kultuurkapitali aastapreemiad: Kristiina Ehini luulekogu "Kaitseala" ja Jürgen Rooste luulekogu "Ilusaks inimeseks", Piret Raud "Sanna ja salakütid", Merle Karusoo näidend "Misjonärid", Madis Kõivu artiklikogumik "Luhta-minek". Tõlkepreemiad tõlkijatele Anu Saluäär, Heili Einasto, Lembi Loigu, Veronika Kivisilla, Risto Järv. Vabaauhind Käbi Laretei. Artiklipreemia Aare Pilv. Venekeelse autori kirjandusauhind Gohar Markosjan-Käsper, Svetlan Semenenko

Urbanisti unistuste kodu linna tuiksoonel / Aivo Vahemets

Index Scriptorium Estoniae

Vahemets, Aivo

2007-01-01

Arhitektuurivõistlusel osalenud arhitektide Mutanen-Salminen-Vaarna OY ja KPME OÜ korterelamu Osten Tor Pärnu mnt. 110, Aare Saksa ja Tomas Björklundi (SWECO FFNS) Admirali Maja Ahtri 6A ja Madis Eegi (AB Eek&Mutso) korterelamu City Residence Liivalaia 21. Põhiplaanid, välisvaated. Kommenteerivad kinnisvaraärimees Üllar Hinno, arhitektid Anne Valing ja Carolina Hunt. Lisaks Aivo Vahemetsa kommentaarid igale majale

Ühinemise ja iseolemise vastuseis. Ideaalid ja reaalsus / Rein Tootmaa

Index Scriptorium Estoniae

Tootmaa, Rein

2001-01-01

Mängufilmid "Keiser ja palgamõrtsukas" ("Jing ke ci qin wang") : režissöör Chen Kaige : Jaapan-Hiina-Prantsusmaa 1999 ja "Tiiger ja draakon" ("Wo hu chang long") : režissöör Ang Lee : Hiina-Hongkong-Ameerika Ühendriigid 2000. Lisa : Aare Ermeli koostatud Chen Kaige ja Ang Lee loomingu lühikokkuvõtted. Kokkuvõte inglise keeles lk. 128

Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation

Directory of Open Access Journals (Sweden)

Jose M. Martin-Garcia

2017-07-01

Full Text Available Crystal structure determination of biological macromolecules using the novel technique of serial femtosecond crystallography (SFX is severely limited by the scarcity of X-ray free-electron laser (XFEL sources. However, recent and future upgrades render microfocus beamlines at synchrotron-radiation sources suitable for room-temperature serial crystallography data collection also. Owing to the longer exposure times that are needed at synchrotrons, serial data collection is termed serial millisecond crystallography (SMX. As a result, the number of SMX experiments is growing rapidly, with a dozen experiments reported so far. Here, the first high-viscosity injector-based SMX experiments carried out at a US synchrotron source, the Advanced Photon Source (APS, are reported. Microcrystals (5–20 µm of a wide variety of proteins, including lysozyme, thaumatin, phycocyanin, the human A2A adenosine receptor (A2AAR, the soluble fragment of the membrane lipoprotein Flpp3 and proteinase K, were screened. Crystals suspended in lipidic cubic phase (LCP or a high-molecular-weight poly(ethylene oxide (PEO; molecular weight 8 000 000 were delivered to the beam using a high-viscosity injector. In-house data-reduction (hit-finding software developed at APS as well as the SFX data-reduction and analysis software suites Cheetah and CrystFEL enabled efficient on-site SMX data monitoring, reduction and processing. Complete data sets were collected for A2AAR, phycocyanin, Flpp3, proteinase K and lysozyme, and the structures of A2AAR, phycocyanin, proteinase K and lysozyme were determined at 3.2, 3.1, 2.65 and 2.05 Å resolution, respectively. The data demonstrate the feasibility of serial millisecond crystallography from 5–20 µm crystals using a high-viscosity injector at APS. The resolution of the crystal structures obtained in this study was dictated by the current flux density and crystal size, but upcoming developments in beamline optics and the

Computational Insights into the High-Fidelity Catalysis of Aminoacyl-tRNA Synthetases

Science.gov (United States)

Aboelnga, Mohamed M.

Obtaining insights into the catalytic function of enzymes is an important area of research due to their widespread applications in the biotechnology and pharmaceutical industries. Among these enzymes, the aminoacyl-tRNA synthetases (aaRSs) are known for their remarkable fidelity in catalyzing the aminoacylation reactions of tRNA in protein biosynthesis. Despite the exceptional execution of this critical function, mechanistic details of the reactions catalyzed by aminoacyl-tRNA synthetases remain elusive demonstrating the obvious need to explore their remarkable chemistry. During the PhD studies reported in this thesis the mechanism of aminoacylation, pre?transfer editing and post?transfer editing catalyzed by different aaRS have been established using multi-scale computational enzymology. In the first two chapters a detailed information about aaRS and the addressed questions was given in addition to an overview of the used computational methodology currently used to investigate the enzymatic mechanisms. The aminoacylation mechanism of threonine by Threonyl-tRNA synthetases, glutamine by Glutaminyl-tRNA synthetases and glutamate by Glutamyl-tRNA synthetases have been clearly unveiled in chapter 3 and 4. Also, valuable information regarding the role of cofactors and active site residues has been obtained. While investigating the post-transfer editing mechanisms, which proceed in a remote and distinct active site, two different scenarios were experimentally suggested for two types of threonyl-tRNA synthetase species to correct the misacylation of the structurally related serine. We explored these two mechanisms as in chapters 5 and 6. Moreover, the synthetic site in which the aminoacylation reaction is catalyzed, is also responsible for a second type of proofreading reaction called pre-transfer editing mechanism. In chapter 7, this latter mechanism has been elucidated for both Seryl-tRNA synthetases and Isoleucyl-tRNA synthetases against their non-cognate substrates

Fabrication Security and Trust of Domain-Specific ASIC Processors

Science.gov (United States)

2016-10-30

production for gray/black market sales, and unauthorized alteration. This paper describes the risk assessment and mitigation in our creation of a...are often well developed and available as textbook examples, in many cases through either open source archives or commercial IPs. We thus focused on...or reliability are also a major concern. Overproduction for gray/black market sales is also a threat. B. Mitigation The purpose of design

Kontsert

Index Scriptorium Estoniae

2005-01-01

Vanemuise kontserdimajas 22. okt.saksa vokaalansambli Singer Pur kontsert "The Sound of Beauty" festivali NYYD'05 raames, 27. okt. Ralf Taali kontsert kammerlaval. Tartu Ülikooli aulas 14. okt. hõimukontsert, 15. okt. ansambli Corelli Consort kontsert "Ajaloo ilu", 19. okt. esinevad bariton Aare Saal ja pianist Pille Paemurru kontserdiasarja "Meistrite Akadeemia" raames, 25. okt TÜ asutamispäeva kontsert "Barokiaja õied baltisaksa, prantsuse ja saksa heliloojatelt" (esineb Corelli Consort)

Eesti Energia IPO nõuab sadu miljoneid kroone / Sulev Vedler

Index Scriptorium Estoniae

Vedler, Sulev, 1970-

2009-01-01

Valitsus ei otsustanud, kas müüa Eesti Energia uued aktsiad maha börsi kaudu või osta need ise ära. Peaministri majandusnõuniku Aare Järvani sõnul on tegemist olulise poliitilise otsusega ja see ei tohi tekitada rahvas pahameelt. Autori sõnul võidaks börsiplaan poolehoidu näiteks siis, kui firma töötajad ja jaekliendid saaksid osta aktsiaid soodustingimustel

Exercise Black Skies 2008: Enhancing Live Training Through Virtual Preparation -- Part Two: An Evaluation of Tools and Techniques

Science.gov (United States)

2009-06-01

visualisation tool. These tools are currently in use at the Surveillance and Control Training Unit (SACTU) in Williamtown, New South Wales, and the School...itself by facilitating the brevity and sharpness of learning points. The playback of video and audio was considered an extremely useful method of...The task assessor’s comments were supported by wall projections and audio replays of relevant mission segments that were controlled by an AAR

Annual Systems Engineering Conference (9th): Focusing on Improving Performance of Defense Systems Programs. Volume 3. Wednesday

Science.gov (United States)

2006-10-26

Bubble and Requirements Management by Mr. Jimmy Thai Cost Efficient Risk Management Through Integrated T&E Throughout the Systems Engineering Life-Cycle...ACSG/ Miller Seven Steps of an Effective Lessons Learned Process by Mr. Jimmy Thai Lessons Learned from a Mature DMSMS Program by SQNLDR P.D.Weeding...Aircraft AAR-47 Missile Warning System (MWS) GTRI_B-9 Lessons Learned with System Integration - 9 Theatre Airborne Reconnaissance System (TARS

Quality control in aminoacyl-tRNA synthesis its role in translational fidelity

DEFF Research Database (Denmark)

Yadavalli, Srujana S; Ibba, Michael

2012-01-01

mechanisms to achieve high levels of accuracy in aminoacylation. Editing functions in aaRSs contribute to the overall low error rate in protein synthesis. Over 40 years of research on aaRSs using structural, biochemical, and kinetic approaches has expanded our knowledge of their cellular roles and quality...... control mechanisms. Here, we review aaRS editing with an emphasis on the mechanistic and kinetic details of the process....

AS Balti Ameerika Auto Keskus Peterburi tee 50

Index Scriptorium Estoniae

1998-01-01

Tallinna 'Chrysleri' ja 'Jeepi' autokeskuse hoonekompleksis on eristatavad kolm osa: kahekorruseline müügisalong, ühekorruseline töökoda ja hooldusruunid, ladu ning olmeplokk. Klaasfassaadiga automüügisaal ulatub hoonest välja sammastega ümbritsetud poolkaarest paadikujulise siiluna. Peatöövõtja: AS Feer Ehituse projektijuht: AS TSM. Projekteerija: Arhitektuuribüroo R. Puusepp. Arhitekt Aare Saks (FFNS, Rootsi). Sisekujundus Rein Nurmse. Projekt 1996, valmis 1997

An Exploration of Cohesion in the Land of Combat Service Support

Science.gov (United States)

1991-12-18

the group AAR the soldier finds that the companions he could not see were doing the same things that he was. Leaders discover actions of subordinates...seventy-eight years, and many wars ago. 39 ENDOUES. £ William Shakespeare , Tie Complete Works of William Shakespeare . (London: Octopus Books, 1986), 478...Beverly Hill, CA: Sage Publications, 1980. Shakespeare , William. The ComDlete Works of William Shakespeare . London: Octopus Books, 1985. Simpkin