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Sample records for zaman xiaoyun guo

  1. Integrating multiple calendars using tau ZAMAN

    DEFF Research Database (Denmark)

    Jensen, Christian Søndergaard; Urgun, B; Dyreson, C. E.

    2007-01-01

    Programmers world-wide are interested in developing applications that can be used internationally. Part of the internationalization effort is the ability to engineer applications to use dates and times that conform to local calendars yet can inter-operate with dates and times in other calendars, ....... Literals can be input and output in XML or plain text, using user-defined formats, and in different languages and character sets. Finally, tZAMAN is a client/server system, enabling shared access to calendar servers spread throughout the web. This paper describes the architecture of t......ZAMAN and experimentally quantifies the cost of using a calendar server to translate and manipulate dates....

  2. Zaman Talukder : L'autonomisation des femmes au moyen de la ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    27 mars 2015 ... Le programme Enhanced Homestead Food Production (EHFP) de l'organisme Helen Keller International bénéficie du soutien technique de Zaman Talukder, expert en agriculture, sécurité alimentaire et nutrition établi au Cambodge. Le travail de Zaman vise à intégrer l'aquaculture d'espèces diverses en ...

  3. Zaman Talukder: Empowering women through food security | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2015-03-23

    Mar 23, 2015 ... That is how Zaman became interested in policy-relevant research. ... Overall, livelihoods improved: food production increased as did fruit and ... of Canada provided through Foreign Affairs, Trade and Development Canada.

  4. ATLANTIC and beyond: an interview with Professor Azfar Zaman.

    Science.gov (United States)

    Zaman, Azfar; Wu, Wing

    2015-01-01

    Professor Azfar Zaman speaks to Wing Wu, Commissioning Editor: Professor Azfar Zaman is a Consultant Interventional Cardiologist at Freeman Hospital and Professor of Cardiology at Newcastle University. Following graduation at Leeds Medical School, he completed postgraduate training in cardiology at regional centres in Leeds, London and Cardiff. Prior to his appointment in Newcastle upon Tyne, he was a Fulbright Scholar and British Heart Foundation International Fellow at Mount Sinai Medical Center, New York, USA. He is the Clinical Lead for Coronary Intervention and Director of the Cardiac Catheter Laboratories. In 2012, he was appointed Specialty Group Lead for Cardiovascular Research and has an interest in clinical research, with a particular interest in atherothrombosis in diabetes and clinical trials.

  5. ASPECTUAL INFLUENCE ON TEMPORAL RELATIONS: A CASE STUDY OF THE EXPERIENTIAL GUO IN MANDARINE

    Directory of Open Access Journals (Sweden)

    Jiun-Shiung Wu

    2009-12-01

    Full Text Available This paper examines how the temporal relation between a clause containing the experiential guo and an adjacent clause is determined. Mandarin is a language not morphologically marked for tenses (e.g., Lin 2006, and therefore, tenses cannot help in determining temporal relations in Mandarin. However, Mandarin has a rich aspectual system. This paper argues that the experiential guo indirectly influences temporal relations via rhetorical relations by either specifying a default rhetorical relation, or by constraining the circumstances under which a certain rhetorical relation can connect a clause with guo to an adjacent clause. This paper also argues that the default rhetorical relation and the constraints are determined by the aspectual properties of the experiential marker. Other information, such as discourse connectors, lexical information, etc., can override the default rhetorical relation indicated by guo and specifies a rhetorical relation. Therefore, this paper concludes that in Mandarin aspect markers can indirectly affect temporal relations by means of rhetorical relations, a result consistent with Wu’s (2005b paper on the perfective marker le in Mandarin, and Wu’s (2007b, 2004 work on the progressive marker zai and the durative marker zhe.

  6. On a conjecture of Chen-Guo-Wang

    OpenAIRE

    Ning, Bo; Zheng, Yu

    2015-01-01

    Towards confirming Sun's conjecture on the strict log-concavity of combinatorial sequence involving the n$th$ Bernoulli number, Chen, Guo and Wang proposed a conjecture about the log-concavity of the function $\\theta(x)=\\sqrt[x]{2\\zeta(x)\\Gamma(x+1)}$ for $x\\in (6,\\infty)$, where $\\zeta(x)$ is the Riemann zeta function and $\\Gamma(x)$ is the Gamma function. In this paper, we first prove this conjecture along the spirit of Zhu's previous work. Second, we extend Chen et al.'s conjecture in the ...

  7. Zamanın Bir Başlangıcı Olmalı mıdır?

    Directory of Open Access Journals (Sweden)

    Zikri Yavuz

    2015-12-01

    Full Text Available Bu makalede, zamanın bir başlangıcı olup olmadığını tartışacağım. Büyük patlama modeline göre, evrenimiz sonsuz bir şekilde geçmişe sahip değildir. Bu, muhtemelen modern kozmolojinin en görkemli keşiflerinden birisidir. Buna rağmen bazı filozoflar zamanın zorunlu olarak bir başlangıcının olmadığını iddia etmektedirler. Büyük patlamanın âlemin zamansal bir başlangıcı olduğu görüşünü desteklediğini ileri süreceğim. Aynı zamanda zamanın başlangıcı olmadığına dair a priori argümanların da başarılı olmadığını göstermeyi deneyeceğim.

  8. Di Bawah Bayang-Bayang Kota: Penataan Daerah di Provinsi Banten dari Zaman Kolonial sampai Zaman Reformasi

    Directory of Open Access Journals (Sweden)

    Radjimo Sastro Wijono

    2017-11-01

    Full Text Available Artikel ini membahas reformasi wilayah yang berlangsung di provinsi termuda di Indonesia yaitu Banten sejak zaman penjajahan Belanda sampai masa reformasi. Reformasi wilayah yang terjadi di daerah ini sangat menarik untuk dipelajari. Situasi politik-ekonomi merupakan faktor utama terjadinya reformasi wilayah di Banten. Dengan menggunakan metode sejarah, perubahan pengaturan wilayah Banten diketahui telah terjadi beberapa kali sejak masa penguasa tradisional (kesultanan yang dilumpuhkan oleh pemerintah kolonial pada abad ke-19 hingga masa reformasi. Pada masa kolonial, Gubernur Jenderal Daendles mereformasi wilayah Banten menjadi tiga kabupaten yaitu Banten Hulu, Banten Hilir, dan Anyer. Sementara itu, pada masa kolonial Inggris wilayah Banten dibagi menjadi empat kabupaten yaitu Banten Lor, Banten Kulon, Banten Tengah, dan Banten Kidul. Perubahan kebijakan reformasi teritorial itu tentu saja membawa dampak dalam bidang politik, ekonomi, dan budaya. Regulasi penataan wilayah di Banten tidak hanya dipengaruhi oleh bayang-bayang situasi politik dan ekonomi dari Jakarta dan Bandung, tetapi juga berdasar pada aspek ekologis serta kepentingan umum masyarakat yang multikultur.

  9. Editorial: The LAMOST survey at the Guo Shou Jing Telescope

    International Nuclear Information System (INIS)

    Bland-Hawthorn, Joss

    2012-01-01

    This special issue is devoted to the LAMOST star/galaxy survey now under way at the Guo Shou Jing Telescope in China. Here I review briefly the LAMOST survey in the context of recent, ongoing and future surveys on the international scene. The primary science goal is to obtain kinematics and abundance information for ten million stars over the Galaxy, far more than all other ground-based surveys combined. This rich trove will provide new insights and understanding about the workings of our Galaxy and its origins.

  10. Epidemiology and outcome analysis of scalds in children caused by "guo lian kang": an 11-year review in a burn center in China.

    Science.gov (United States)

    Zhu, Liqiang; Zhang, Hong; Shi, Fusheng; Yi, Dong; Zhu, Guangjun

    2015-03-01

    The objective of this study was to investigate the epidemiological characteristics of scalds induced by "guo lian kang" (literally "stove connected to bed") in children. The demographic, burn features, outcome, and other information of 0-14-year-old children with "guo lian kang"-induced scalds admitted to the burn treatment center of the 322 Hospital of the People's Liberation Army in Datong from 30 September 2001 to 31 December 2011 were analyzed. Among the 1993 children clearly documented with scalds due to hot liquid in vessels, 795 (39.89%) had burns due to "guo lian kang." The proportion of the pediatric burns caused by "guo lian kang" was 55.56% in 2002 and 37.30% in 2011, with a decreasing trend. One-year-old children accounted for the highest proportion of children with burns due to "guo lian kang" (male:female=1.54:1). Scalding mostly occurred from October to May; the most common times were around 8:00 AM, 11:00 AM, and 7:00 PM. Most scalds occurred on the upper limbs, 90.22% of which were dermal burns. The median burn area was 11% of the total body surface area. The burn agent was mainly hot water in pots. Scalding mostly occurred when the children accidentally sat on, or fell or stepped into the pot while playing. Among the children with "guo lian kang"-induced scalds, up to 42.26% of the children did not receive any treatment before hospital admission, and 18.86% of the children were admitted to the hospital ≥6h after the occurrence of burns. In addition, 74.97% of the children's families can afford the medical expenses, while 5.28% abandoned treatment because of financial difficulties. There were no significant differences between children with scalds caused by "guo lian kang" and scalds caused due to other reasons considering the age and sex. Compared to scalds due to other reasons, children with "guo lian kang"-induced scalds had greater burn area and depth, shock incidence, surgery rate, blood transfusion rate, length of hospital stay, and

  11. China Dimensions Data Collection: GuoBiao (GB) Codes for the Administrative Divisions of the Peoples Republic of China

    Data.gov (United States)

    National Aeronautics and Space Administration — GuoBiao (GB) Codes for the Administrative Divisions of the People's Republic of China consists of geographic codes for the administrative divisions of China. The...

  12. Postmodern Roman’da Anlatıcı, Zaman ve Mekân Yapısı Narrator, Time and Space Structure of Postmodern Novel

    Directory of Open Access Journals (Sweden)

    Gamze ÖZOT

    2012-09-01

    are given to reader and it is -expected from the reader to create rest of it in the mind. The space socalled“hyper space” by postmodernists is variable in postmodernnovels; it can not demonstrate a clear stance. Metinlerarasılık ve üstkurmaca tekniklerinin sıkça kullanıldığı, modern romanlardakinin aksine özneye değil de söylemin kendisine odaklanan, tarihi gerçeklerle kurguyu iç içe vererek tarihten yararlanan postmodern roman sıra dışı kurgusuyla dikkatleri üzerine çekmeyi başarır. Postmodern romanda anlatıcı, mekân ve zaman yapıları modern roman ve yansıtmacı romana göre ilginç farklılıklar gösterir. Postmodern romanın yazarı çoğul anlatıcı tekniğiyle okuru şaşırtırken, “hyper mekân” yapısının değişkenliği ve bir arada verilmiş farklı zaman dilimlerinin yapısıyla okuyucuyu alışık olmadığı bir âlemin içinde tek başına bırakır. Postmodern romanda anlatıcı oldukça etkin bir rol üstlenir. Figüratif kadronun önemli bir elemanı olabileceği gibi kurgunun yazılım aşamasına müdahale etmesi de söz konusudur. Sık sık fikir beyan eder ve adeta romanı yönlendirir. Postmodern romanın anlatıcısı bu yönüyle okuyucuyu peşinden sürükler, meraklandırır ve kimi zaman da gülümsetir. Postmodern romanlarda çizgisel, kronolojik zaman kullanımının çoğunlukla kırılmaya çalışıldığı gözlemlenir. “Şimdi”nin, anında aktarmanın belirgin bir şekilde öne çıktığı postmodern romanlarda zaman klasik ve modern tarzdaki romanlara oranla önemsizleştirilmiştir. Zamana ait birimler, yani nesnel zaman -gün, ay, yıl...- postmodern romanlarda ya karmaşıklaştırılır ya kronolojisi altüst edilerek kullanılır ya da üstü örtük, belirsiz bir şekilde verilir. Bununla birlikte postmodern romanda, metnin yazılış zamanı ile kurgunun zamanı koşut kılınabilir. Daha somut bir ifadeyle metnin yazılma süreci, okuyucunun o anda elinde tuttuğu romanın ana

  13. The site conditions of the Guo Shou Jing Telescope

    International Nuclear Information System (INIS)

    Yao Song; Liu Chao; Zhang Haotong; Deng Licai; Zhang Yueyang; Li Jing; Liu Nian; Zhou Xu; Gao Shuang; Xu Yan; Newberg, Heidi Jo; Carlin, Jeffrey L.; Chen Li; Hou Jinliang; Christlieb Norbert; Han Zhanwen; Lee, Hsu-Tai; Liu Xiaowei; Pan Kaike; Wang Hongchi

    2012-01-01

    The weather at the Xinglong Observing Station, where the Guo Shou Jing Telescope (GSJT) is located, is strongly affected by the monsoon climate in northeast China. The LAMOST survey strategy is constrained by these weather patterns. We present statistics on observing hours from 2004 to 2007, and the sky brightness, seeing, and sky transparency from 1995 to 2011 at the site. We investigate effects of the site conditions on the survey plan. Operable hours each month show a strong correlation with season: on average there are eight operable hours per night available in December, but only one—two hours in July and August. The seeing and the sky transparency also vary with season. Although the seeing is worse in windy winters, and the atmospheric extinction is worse in the spring and summer, the site is adequate for the proposed scientific program of the LAMOST survey. With a Monte Carlo simulation using historical data on the site condition, we find that the available observation hours constrain the survey footprint from 22 h to 16 h in right ascension; the sky brightness allows LAMOST to obtain a limiting magnitude of V = 19.5 mag with S/N=10.

  14. PARAÇALI REGRASYON YARDIMIYLA BİTKİ BOYU ZAMAN İLİŞKİSİ PARAMETRELERİNİN TAHMİNİ

    Directory of Open Access Journals (Sweden)

    UFUK KARADAVUT

    2005-01-01

    Full Text Available Bu çalışma Bahri Dağdaş Uluslararası Tarımsal Araştırma Enstitüsü Deneme alanlarında yürütülmüştür. Çalışmada Dağdaş-94 buğday çeşiti kullanılmıştır. Bitkilerde lO'ar gün aralıklarla düzenli olarak 15 kez boy ölçümleri yapılmıştır. Her parselden 5 bitki tesadüfen alınmış ve üç tekrarlamalı olarak yapılan ölçümlerde, her ölçüm için toplam J 5 bitki kullanılmıştır. Buğday bitkisinin boyunun zamana göre modellenınesi ve model parametrelerinin tahmini uygulaına yönünden önem arzetmektedir. Bu amaçla, doğrusal olmayan bir model gösteren bitkinin boy uzunluğu ile zaman ilişkisi, belli noktalarda zıplamalar gösterirken bazı noktalarda kesilmeler gösterebilmektedir. Bu çalışmamızda buğday bitkisinin boy uzunluğu ve zaman ilişkisi açısından parçalı regresyon modelinin parametre tahmini ve zıplama noktalarının tahmin edilmesi ele alınmıştır

  15. Hasat Zamanının Nar Suyunun Şeker ve Organik Asit Bileşimleri Üzerine Etkisi

    Directory of Open Access Journals (Sweden)

    Muharrem Gölükcü

    2015-02-01

    Full Text Available Bu çalışmada ülkemizde ticari olarak yetiştirilen Hicaznar çeşidinin hasat zamanına göre meyve suyunun, suda çözünür kurumadde miktarı (SÇKM, pH, titrasyon asitliği (susuz sitrik asit gibi temel özelliklerin yanında şeker ve organik asit bileşimleri tespit edilmiştir. Araştırma kapsamında analize alınan örnekler beş farklı dönemde hasat edilmiş, analiz edilen kalite karakteristikleri hasat zamanları arasında istatistiksel olarak önemli farklılıklar göstermiştir. Nar suyunun bilişiminde tespit edilen organik asitlerden sitrik, malik, okzalik ve tartarik asit miktarları sırasıyla 6.70-10.19 g/L, 0.28-0.48 g/L, 0.23-0.41 g/L, 0.03-0.09 g/L; örneklerin bileşiminde tespit edilen fruktoz, glikoz, sakkaroz ve maltoz miktarları da sırasıyla %7.69-8.34, %5.44-5.7, %0.08-0.19, %0.59-0.68 değerleri arasında dağılım göstermiştir. Araştırma hasat zamanındaki ilerlemeyle narın şeker içeriğinde artış, asitlik miktarında ise azalış olduğunu göstermiştir.

  16. ÖĞRETMENLERİN SERBEST ZAMAN EĞİTİMİ VE REKREASYON (SERBEST ZAMANDA YAPILAN AKTİVİTELER) ETKİNLİKLERİNE KATILIMLARINDAKİ SOSYO, EKONOMİK, KÜLTÜREL ETKENLER- DÜZCE ÖRNEĞİ

    OpenAIRE

    AŞKIN, Cevdet

    2016-01-01

    Serbest zaman etkinliklerinin başarı ve verimlilik süreci olarak düşünülmesinin ülke gelişimine katkısı son yıllarda önemli derecede kabul görmüştür. Eğitim-öğretim sahasında, geleneksel metodların yerini teknolojik gelişmeler almıştır. Her yerde, her zaman, her durumda eğitimin sürdürülmesi öğretmenlerimizin kendilerinde farklı bir rol üstlenmesi gerektiği düşünülmektedir. Eğitim-öğretimin ana unsuru olan öğretmenlerin serbest zamanlarını iyi bir şekilde değerlendirmeleri iş verimliliğini mü...

  17. FİNANSAL VEKTÖREL ZAMAN DİZİLERİNDE ÖZDEĞER-ÖZVEKTÖR ANALİZİYLE EŞZAMANLI VE GECİKMELİ DOĞRUSAL İLİŞKİLERİN TESBİTİ

    Directory of Open Access Journals (Sweden)

    REŞAT KASAP

    2013-05-01

    Full Text Available Bu çalışmada, vektörel zaman dizilerinde modelleme aşamasında, dizilerin birbirleriyle ilişkilerini ortaya koyan eşzamanlı ve gecikmeli doğrusal ilişkilerin tesbiti, iki farklı gerçek veri grubu üzerinde gösterilmiştir. Bunlardan birincisi, üç diziden oluşan Ziraat Bankası(TCZB’nın verdiği kredi dizileridir. Diğeri ise, ABD Doları’nın BP(İngiliz Sterlini, DM(Alman Markı, SF(İsviçre Frangı, ve YEN(Japon Yeni’e göre değişimlerini veren dört dizidir. Analizler sonucunda vektör AR(1 ile modellenen her iki grupdan; birincisinde doğrusal ilişkilerin her ikisinin de olmadığı, diğer veri grubunda ise her iki ilişkinin de var olduğu görülmüştür.

  18. Membaca Pertanda Zaman (Eksploitasi Alam oleh Manusia: Sebuah Interpretasi dalam Karya Seni Patung

    Directory of Open Access Journals (Sweden)

    Yoga Budhi Wantoro

    2014-11-01

    Full Text Available Membaca Pertanda Zaman (Eksploitasi Alam oleh Manusia: Sebuah Interpretasi dalamKarya Seni Patung mewakili bentuk-bentuk eksploitasi alam yang dilakukan olehmanusia adalah sebuah konsep penciptaan karya seni patung sebagai ungkapanpribadi penulis dalam menanggapi, merespons, dan merasakan fenomena eksploitasiyang kebablasan. Berdasarkan observasi, ide, dan sikap kreatif, penulis mencobamenafsirkan dan merepresentasikan gejala serta bentuk eksploitasi alam tersebutdalam bahasa patung yang kaya dengan unsur bentuk, ruang, dan volume. Konsepini, menjadikan alam sebagai objek eksploitasi yang direpresentasikan dalam bentukbatu alami yang sekaligus menjadi media penulis untuk membaca pertanda zaman.Selain itu, konsep etika lingkungan seperti Biosentrime dan konsep kejawen,yaitu Hamemayu Hayuning Bawana (bhs. Jawa yang menjadi jiwa agar kelahiranpatung tersebut menjadi simbol keseimbangan antara manusia dan alam. Dalamhal ini sebongkah batu sebagai metafora dari alam dipecah, diiris, dibor, dan digesersebagai sebuah simbol bentuk eksploitasi yang dilakukan manusia terhadap alam.Kontradiksi antara manusia berteknologi dengan alam, dimetaforakan dalam prosesberkarya, yaitu dengan menggunakan peralatan mekanik ataupun mesin. Alat tersebutsebagai ekses dari perlakukan manusia terhadap alam demi kepentingan dankelangsungan hidup manusia. Sikap penulis yang tetap menghargai alam ditranformasikandalam wujud karya dengan membiarkan karakter batu tetap terjaga alamiahnya.Hasil penciptaan karya seni patung ini, selain memunculkan nilai estetik danbermakna simbolis, juga memberikan corak baru dalam seni rupa khususnya senipatung, serta memberikan ciri khas jati diri penulis dalam penciptaan seni patung. Understanding the Sign of an Era: Nature Exploitation by Human Being- anInterpretation on the Works of Sculpture. Understanding the sign of an era throughthe art of sculpture is one of writer’s expressions in interpreting the form of natureexploitation by

  19. Müzik Eğitimi Anabilim Dalı Öğrencilerinin Zaman Yönetimi Becerileri/The Time Management Skills of Music Education Students

    OpenAIRE

    Babacan, Yrd.Doç.Dr.Ezgi; Küçükosmanoğlu, Dr.Hayrettin Onur

    2015-01-01

    ÖZETBu araştırmanın amacı müzik eğitimi anabilim dalı öğrencilerinin zaman yönetimi becerilerini belirlemek ve bu becerilerin cinsiyet, yaş, sınıf ve bireysel çalgılarına göre değişkenlik gösterip göstermediğini saptamaktır. Araştırmada ilişkisel tarama modeli kullanılmıştır. Araştırmanın örneklemini 2014–2015 eğitim-öğretim yılında Necmettin Erbakan Üniversitesi A.K.E.F. Müzik Eğimi Anabilim Dalı'nda öğrenimine devam eden 128 öğrenci oluşturmaktadır. Verilerin toplanmasında Britton ve T...

  20. Dangshen (Codonopsis pilosula) and Bai guo (Gingko biloba) enhance learning and memory.

    Science.gov (United States)

    Singh, Betsy; Song, Howin; Liu, Xiao-Dong; Hardy, Mary; Liu, Gan-Zhong; Vinjamury, Sivarama P; Martirosian, Claudia Der

    2004-01-01

    An exploration of the usefulness of several common Chinese herbs used for Acquisition and Retention singly or in combination is required. To test (1) whether Gingko biloba (Bai guo) in combination with Codonopsis pilosula (Dangshen) or Gingko biloba (GB) alone could enhance memory acquisition and retention of normal human subjects, better than a placebo and (2) to investigate whether the overall health status can be affected by these supplements. A double blind randomized placebo controlled trial design was used to determine the efficacy of these two products compared to placebo. Sixty participants, aged 21- 60 years, who were either students or faculty of the Southern California University of Health Sciences. Each combination capsule was made up of 75mg of Codonopsis pilosula total glycosides and 40mg GB extract. Each GB capsule consisted of 40mg of Gingko biloba as an aqueous extract and. The placebo pill was similar in shape and color to that of the other two capsules. All the participants regardless of the group were instructed to take one pill twice a day with food. The primary outcome measure was a computerized, standardized acquisition and retention test provided by Digital Acumen, Inc. The secondary outcome measures were the SF-12 and the Medical Symptom Questionnaire ( 1997 healthcomm International, Inc. And Immuno Laboratories, Inc.) Mean age was 28 years; almost two thirds of the sample were males. The study adopted repeated measure analysis using data from three measurement points for between group analysis. GB group was compared to placebo, and CPG/GB group was also compared to placebo. These individual comparisons were made to determine whether the active products produced better results than chance. The between groups findings indicate that both products are better than placebo at producing improvements in acquisition and retention and overall health status. In our participant population, the combination product seems to be better than GB alone in

  1. Annals of Humanities and Development Studies - Vol 5, No 1 (2014)

    African Journals Online (AJOL)

    Will BRICS Development Bank Change the International Financing Architecture? - Predictions and Reality · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. ATMT Islam, L Xiaoyun, 42-56 ...

  2. The effect of smoking on the urinary excretion of 8-oxodG and 8-oxoGuo in patients with type 2 diabetes

    DEFF Research Database (Denmark)

    Sørensen, Anne-Sofie; Kjær, Laura Kofoed; Petersen, Kasper Meidahl

    2017-01-01

    as urinary 8-oxo-7, 8-dihydro-2'-deoxyguanosine (8-oxodG) excretion in smokers compared with non-smokers in a healthy population. We aimed to investigate if an increased urinary excretion of 8-oxodG in smokers versus never smokers and former smokers could be verified in a population with type 2 diabetes......Over the past decades, attention has been paid to understanding the impact of oxidative stress and related modifications of DNA and RNA on various human health risks. A recent meta-analysis comprising 1915 smokers and 3462 non-smokers found a significantly higher level of DNA oxidation measured...... to examine the relationship between daily smokers (n = 462) versus former (n = 1341) and never smokers (n = 918) regarding the RNA and DNA oxidation, respectively. We did not find any significant effect of smoking on urinary excretion of 8-oxodG or 8-oxoGuo in our study. Due to a sparse study area...

  3. "We chose the mentors carefully" | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2011-07-08

    Jul 8, 2011 ... Liu Xiaoyun, an associate professor at China Agricultural University in Beijing, ... Her research has been published in a Chinese-language journal, in a paper ... Building bridges in economics research: John Whalley (Canada).

  4. Cardiovascular and All-Cause Mortality Risk Associated With Urinary Excretion of 8-oxoGuo, a Biomarker for RNA Oxidation, in Patients With Type 2 Diabetes

    DEFF Research Database (Denmark)

    Kjær, Laura K.; Cejvanovic, Vanja; Henriksen, Trine

    2017-01-01

    patients. We assessed whether 8-oxoGuo is associated with specific cardiovascular and all-cause mortality risk. RESEARCH DESIGN AND METHODS: Urinary biomarkers for nucleic acid oxidation were measured in a cohort of patients with type 2 diabetes aged ≥60 years (n = 1,863), along with biochemical...... measurements, questionnaire findings, and Central Person Registry information to estimate the hazard ratios (HRs) for log2-transformed RNA oxidation using Cox regression. RESULTS: During the 5-year follow-up, 173 of 1,863 patients had died (9.3%), including 73 patients who died of cardiovascular disease (42.......10 [95% CI 4.00-8.30]) and cardiovascular mortality (AR 5.49 [95% CI 3.44-7.55] vs. AR 3.16 [95% CI 1.59-4.73]) were approximately two times higher in the highest quartile of RNA oxidation than in the lowest quartile. CONCLUSIONS: We conclude that high RNA oxidation is associated with all...

  5. Learning from the Field : Innovating China's Higher Education System

    International Development Research Centre (IDRC) Digital Library (Canada)

    2008-04-15

    Learning from the Field : Innovating China's Higher Education System. Couverture du livre Learning from the Field : Innovating China's Higher Education System. Editor(s):. Ronnie Vernooy, Li Xiaoyun, Xu Xiuli, Lu Min, et Qi Gubo. Publisher(s):. Foundation Book, CRDI. April 15, 2008. ISBN: 9788175966017. 260 pages.

  6. Sustainable reverse logistics for household plastic waste

    NARCIS (Netherlands)

    Bing, X.

    2014-01-01

    Summary of the thesis titled “Sustainable Reverse Logistics for Household Plastic Waste”

    PhD Candidate: Xiaoyun Bing

    Recycled plastic can be used in the manufacturing of plastic products to reduce the use of virgin plastics material. The cost of recycled plastics is usually lower

  7. Genomic dissection and prioritizing of candidate genes of QTL for ...

    Indian Academy of Sciences (India)

    Genomic dissection and prioritizing of candidate genes of QTL for regulating spontaneous arthritis on chromosome 1 in mice deficient for interleukin-1 receptor antagonist. Yanhong Cao, Jifei Zhang, Yan Jiao, Jian Yan, Feng Jiao, XiaoYun Liu, Robert W. Williams, Karen A. Hasty,. John M. Stuart and Weikuan Gu. J. Genet.

  8. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics; Volume 91; Issue 2. Genomic dissection and prioritizing of candidate genes of QTL for regulating spontaneous arthritis on chromosome 1 in mice deficient for interleukin-1 receptor antagonist. Yanhong Cao Jifei Zhang Yan Jiao Jian Yan Feng Jiao Xiaoyun Liu Robert W. Williams Karen ...

  9. Hıyarda (Cucumis sativus L. yabancı ot çıkış zamanın tahminine yönelik araştırmalar

    Directory of Open Access Journals (Sweden)

    Nihat Tursun

    2015-01-01

    Full Text Available İstatistiki modellerin geliştirilmesi için hıyar bitkisinde on bir önemli yabancı otun çıkış zamanın belirlenmesinde modellemeler yapılmıştır. Hıyar deneme arazisinde bulunan önemli yabancı otlar çıkış zamanlarına göre gruplara ayrılmıştır. Bu yabancı otlardan; Amaranthus retroflexus, Chenopodium album, Heliotropium europaeum, Polygonum aviculare ve Solanum nigrum erken, Convolvulus arvensis, Cyperus rotundus, Cynodon dactylon, Portulaca oleracea ve Sorghum halepense bütün vejetasyon boyunca ve Tribulus terrestris ise geç çimlenen yabancı ot türü olarak belirlenmiştir. Farklı doğrusal olmayan büyüme eğrileri (Chapman-Richard, Weibull, logistic, Gompertz ve cubic spline farklı yabancı ot türleri ve yıllar için çıkış yüzdeleri verileri esas alınarak uyarlanmıştır. Cubic splin model birçok yabancı ot türü için en iyi model olarak saptanmıştır.

  10. Hasat Zamanı ve Hasat Sonrası Olgunluğa Bağlı Olarak Bazı Avokado (Persea americana Mill Çeşitlerinin Bileşimindeki Değişimler

    Directory of Open Access Journals (Sweden)

    Feramuz Özdemir

    2015-02-01

    Full Text Available Bu araştırmada Bacon, Fuerte, Hass ve Zutano çeşidi avokado (Persea americana Mill meyvelerinin bazı fiziksel ve kimyasal özelliklerinin hasat zamanı ve hasat sonrası olgunlaşma periyoduna göre değişimi belirlenmiştir. Ortalama meyve eti oranı %81.3 olan örneklerde toplam kuru madde %21.88-26.25, yağ %12.22-17.28, protein %1.63-2.42, kül %0.94-1.27 ve titre edilebilir asit miktarı %0.08-0.11 (sitrik asit değerleri arasında değişmiştir. Avokado yağında en fazla oleik asit {%49.66-66.51 bulunurken, bu yağ asilini, palmitik asit (%15.35-22.26 ve linoleik asit (%9.88-15.60 izlemiştir. Meyvede mineral maddelerden potasyum 4396-5882 mg/kg, magnezyum 179.8-259.1 mg/kg, kalsiyum 73.49-99.70 mg/kg, sodyum 16.64-27.48 mg/kg, demir 1.88-6.07 mg/kg, bakır 2.24-3.42 mg/kg, çinko 3.09-4.95 mg/kg ve mangan 0.73-1.21 mg/kg değerleri arasında değişim göstermiştir. Avokado hasatının geciktirilmesi ile meyve ağırlığı, toplam kuru madde, yağ ve protein miktarının arttığı saptanmıştır. Aynı zamanda örneklerin yağ asidi kompozisyonunun hasat zamanına göre değiştiği, geç hasatla birlikte oleik asit oranı artarken, diğer yağ asitlerinin oranı ya azalmış ya da değişmemiştir. Hasat sonrası olgunlaşma döneminde ise yağ asitleri bakımından doymamışlık oranının arttığı saptanmıştır.

  11. Osmanlı’da Zaman-Mekân Kavrayışının Değişimi; Edebi Metinler Üzerinden Bir İrdeleme Change In The Ottoman Space-Time Conception; An Inquiry Through Ottoman Literary Texts

    Directory of Open Access Journals (Sweden)

    Işıl UÇMAN ALTINIŞIK

    2012-12-01

    patternsshould be assessed as definition of Ottoman pre-modernity. They standout to manifest other rhythms such as psycho-social and cultural ones.Hence, the proposition of a rhythmic order based on empiricalobservation of nature and especially skies to comprehend temporalspace-time and a shift to a modern space-time which replaces naturewith a new order is justified and posited. Accordingly, the secondchapter aims to discuss the disengagement in temporal space-timeconception occurring in the transformation from traditional to modern.The intention is to demonstrate the social and cultural relation of thedisengagement with the modern period. Hence this chapter studies the exemplary texts on disengagement and the figures that have taken disengagement as their agenda in their texts. Ahmet Mithat‟s „Adab-ı Muaşeret yahut Alafranga (Forms of Politeness or the French Style‟, Ahmet Rasim‟s „Şehir Mektupları (Urban Mail‟, Hasan Hamid‟s „Şems-i Tarih - Zeval-i Saat (Dissolution of Time‟, Ahmet Samim‟s „Vaktimizi Bilelim (Know Our Hour‟, Ahmet Haşim‟s „Müslüman Saati (Muslim Clock‟ and Ahmet Hamdi Tanpınar‟s „Saatleri Ayarlama Enstitüsü (The Calibration Institute of Clocks‟ are the exemplary texts to discuss the change in space-time conception. The assessment section associates the texts to each other and the topic. „Disengagement of exilic moon calendar‟, „disengagement of Ottoman time‟, „disengagement of day-night demarcation‟ are the cases of this chapter. Bu çalışma ile öngörülen, teknokültürel ve sosyokültürel incelemeler bağlamında Osmanlı‟da, modern öncesi pratiklerden moderne olan dönüşüm sürecine dair yapılan araştırmalarda ihmal edilmiş bir konuyu, son dönemlerde gün yüzüne çıkarılan arşiv ve literatür çalışmaları ile birlikte gündeme taşımaktır. Çizilen bu çerçeve içinde Osmanlı‟da zaman-mekân kavrayışındaki değişim, söz konusu kültürel ortamda yaşanan toplumsal

  12. ÜÇ MAYMUN, PANDORA’NIN KUTUSU, GÜZEL GÜNLER GÖRECEĞİZ, NAR, GERİYE KALAN, ŞİMDİKİ ZAMAN VE ZERRE FİLM ÖRNEKLERİYLE: TÜRK SİNEMASINDA KENTLİ KADIN OLGUSU

    Directory of Open Access Journals (Sweden)

    Gül Yaşartürk Yaşartürk

    2015-01-01

    Full Text Available Türk sinemasında ilk yıllarından başlamak üzere sınıf farkı, kültür farkı, yaşam biçimi, giyim-kuşam, aile ve cinsiyet rollerinde modern ve geleneksel karşıtlıkları çoğu zaman kent ve taşra ayrımında ortaya konulur. Bu filmlerde çoğu zaman, dürüst, ahlaklı, değerlerine bağlı ve inançlı olmak, namus ve şeref gibi değerler taşra kültürü ile özdeşleştirilirken, modern, Batılı yaşam tarzı, aile, inanç ve değerlerinden uzaklaşmış, ahlaki çöküntü içinde yaşayan, içki ve ihanetin pençesinde kıvranan kentlilere, dolayısıyla kent kültürüne dayatılır. Ancak özellikle 1940’lı yıllardan başlayan ve hızla devam eden taşradan kente göçle birlikte taşra kent, merkez ve periferisi bağlamında kent ve kentli kavramları da değişim ve dönüşüme uğramıştır.  Bu çalışmada günümüz Türk sinemasında kentli kadın olgusunu kadın ve kent ilişkisi bağlamında örnek film analizleriyle ortaya koymayı amaçlamaktadır. Bu amaçla 2000’li yıllardan itibaren Türk sinemasında kentli kadın temsilleri yedi film örneğinde niteliksel içerik analizi yöntemi ile incelenecektir.

  13. Consensus statement on definition, diagnosis, and management of high-risk prostate cancer patients on behalf of the Spanish Groups of Uro-Oncology Societies URONCOR, GUO, and SOGUG.

    Science.gov (United States)

    Henríquez, I; Rodríguez-Antolín, A; Cassinello, J; Gonzalez San Segundo, C; Unda, M; Gallardo, E; López-Torrecilla, J; Juarez, A; Arranz, J

    2018-03-01

    Prostate cancer (PCa) is the most prevalent malignancy in men and the second cause of mortality in industrialized countries. Based on Spanish Register of PCa, the incidence of high-risk PCa is 29%, approximately. In spite of the evidence-based beneficial effect of radiotherapy and androgen deprivation therapy in high-risk PCa, these patients (pts) are still a therapeutic challenge for all specialists involved, in part due to the absence of comparative studies to establish which of the present disposable treatments offer better results. Nowadays, high-risk PCa definition is not well consensual through the published oncology guides. Clinical stage, tumour grade, and number of risk factors are relevant to be considered on PCa prognosis. However, these factors are susceptible to change depending on when surgical or radiation therapy is considered to be the treatment of choice. Other factors, such as reference pathologist, different diagnosis biopsy schedules, surgical or radiotherapy techniques, adjuvant treatments, biochemical failures, and follow-up, make it difficult to compare the results between different therapeutic options. This article reviews important issues concerning high-risk PCa. URONCOR, GUO, and SOGUG on behalf of the Spanish Groups of Uro-Oncology Societies have reached a consensus addressing a practical recommendation on definition, diagnosis, and management of high-risk PCa.

  14. Sensitive radioimmunoassay for detection of O6-ethyldeoxyguanosine in DNA exposed to the carcinogen ethylnitrosourea in vivo or in vitro

    International Nuclear Information System (INIS)

    Mueller, R.; Rajewsky, M.F.

    1978-01-01

    O 6 -ethyl-2'-deoxyguanosine (O 6 -EtdGuo) is a major premutational product formed in both intracellular DNA and in purified DNA in vitro, after exposure to the potent alkylating carcinogen N-ethyl-N-nitrosourea (EtNU). Antibodies directed against O 6 -EtdGuo were obtained by immunizing rabbits with a conjungate of O 6 -EtGuo and bovine serum albumin. In a competitive radioimmunoassay (RIA), with O 6 -Et(8,5' 3 H)dGuo as a tracer and various alkylated and natural nucleic acid components as inhibitors, these antibodies show high specificity for O 6 -EtdGuo and detect this product at a level of 0.3 picomol (antibody association constant, 7x10 8 l/mol). In a sample of 130 μg of hydrolyzed DNA, O 6 -EtdGuo can thus be measured at a molar ratio of O 6 -EtdGuo/2'-deoxyguanosine of about 3x10 -6 , i. e., about 5X10 3 O 6 -EtdGuo molecules per diploid cell. Examples are given for the quantitation of O 6 -EtdGuo in DNA exposed to EtNU in vivo or in vitro. (orig.) [de

  15. Repair Activity of trans-Resveratrol toward 2'-Deoxyguanosine Radicals.

    Science.gov (United States)

    Cheng, Xing; An, Ping; Li, Shujin; Zhou, Liping

    2018-04-26

    In the present study, the repair activity of trans-resveratrol toward 2'-deoxyguanosine (dGuo) radicals in polar and nonpolar solvents was studied using density functional theory. The hydrogen transfer/proton coupled electron transfer and single electron transfer (SET) mechanisms between trans-resveratrol and dGuo-radicals were considered. Taking into consideration the molar fraction of neutral trans-resveratrol (ROH) and anionic trans-resveratrol (RO - ), the overall rate constants for repairing dGuo-radicals by trans-resveratrol are 9.94 × 10 8 and 2.01 × 10 9 dm 3 mol -1 s -1 in polar and nonpolar solvents, respectively, and the overall rate constant of repairing cation radical (dGuo •+ ) by trans-resveratrol via an SET mechanism is 7.17 × 10 9 dm 3 mol -1 s -1 . The repair activity of RO - toward dGuo-radicals is better than that of ROH, but the repair activity of ROH toward dGuo •+ is better than that of RO - . Unfortunately, neither ROH nor RO - can repair the 2'-deoxyribose radicals of dGuo. It can therefore be concluded that trans-resveratrol is an effective antioxidant for repairing base radicals of dGuo and dGuo •+ . The study can help us understand the repair activity of trans-resveratrol toward dGuo radicals.

  16. Guanosine may increase absence epileptic activity by means of A2A adenosine receptors in Wistar Albino Glaxo Rijswijk rats.

    Science.gov (United States)

    Lakatos, Renáta Krisztina; Dobolyi, Árpád; Todorov, Mihail Ivilinov; Kékesi, Katalin A; Juhász, Gábor; Aleksza, Magdolna; Kovács, Zsolt

    2016-06-01

    The non-adenosine nucleoside guanosine (Guo) was demonstrated to decrease quinolinic acid(QA)-induced seizures, spontaneously emerged absence epileptic seizures and lipopolysaccharide(LPS)-evoked induction of absence epileptic seizures suggesting its antiepileptic potential. It was also described previously that intraperitoneal (i.p.) injection of 20 and 50mg/kg Guo decreased the number of spike-wave discharges (SWDs) in a well investigated model of human absence epilepsy, the Wistar Albino Glaxo Rijswijk (WAG/Rij) rats during 4th (20mg/kg Guo) and 3rd as well as 4th (50mg/kg Guo) measuring hours. Guanosine can potentially decrease SWD number by means of its putative receptors but absence epileptic activity changing effects of Guo by means of increased extracellular adenosine (Ado) cannot be excluded. An increase in the dose of i.p. injected Guo is limited by its low solubility in saline, therefore, we addressed in the present study whether higher doses of Guo, diluted in sodium hydroxide (NaOH) solution, have more potent antiepileptic effect in WAG/Rij rats. We confirmed that i.p. 50mg/kg Guo decreased but, surprisingly, i.p. 100mg/kg Guo enhanced the number of SWDs in WAG/Rij rats. Combined i.p. injection of a non-selective Ado receptor antagonist theophylline (5mg/kg) or a selective Ado A2A receptor (A2AR) antagonist SCH 58261 (7-(2-phenylethyl)-5-amino-2-(2-furyl)-pyrazolo-[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine) (1mg/kg) and a cyclooxygenase 1 and 2/COX-1 and COX-2 inhibitor indomethacin (10mg/kg) with 100mg/kg Guo decreased the SWD number compared to i.p. 100mg/kg Guo alone. The results suggest that i.p. 100mg/kg Guo can increase SWD number by means of the adenosinergic system. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Design, synthesis, and evaluation of VEGFR-targeted macromolecular MRI contrast agent based on biotin?avidin-specific binding

    OpenAIRE

    Liu, Yongjun; Wu, Xiaoyun; Sun, Xiaohe; Wang, Dan; Zhong, Ying; Jiang, Dandan; Wang, Tianqi; Yu, Dexin; Zhang, Na

    2017-01-01

    Yongjun Liu,1 Xiaoyun Wu,1 Xiaohe Sun,1 Dan Wang,1 Ying Zhong,1 Dandan Jiang,1 Tianqi Wang,1 Dexin Yu,2 Na Zhang1 1School of Pharmaceutical Science, Shandong University, 2Department of Radiology Medicine, Qilu Hospital, Jinan, People’s Republic of China Abstract: Developing magnetic resonance imaging (MRI) contrast agents with high relaxivity and specificity was essential to increase MRI diagnostic sensitivity and accuracy. In this study, the MRI contrast agent, vascular endotheli...

  18. 2000'lerin Başında Türkiye'nin Enerji Politikası

    Directory of Open Access Journals (Sweden)

    Naci ENGİN

    2008-04-01

    Full Text Available Bu makalede Türkiye'de zaman içinde artan enerji ihtiyacını karşılamak için kullanılan enerji kaynaklarının değişimi ele alınmış ve zaman içinde değişen enerji kaynaklarının yurtiçi ve yurtdışı kaynaklardan ne ölçüde yararlanıldığı incelenmiştir. Zaman içinde artan enerji ihtiyacını karşılamak için bilhassa yakın yıllarda yurtdışı kaynakların daha da önem kazandığı hatta enerji kaynaklarının % 80'ine yakınının (petrol, doğalgaz yurtdışı kaynaklardan karşılandığı görülmüştür. Alınacak tedbirlerle yurtiçi kaynak kullanımının zaman içinde artabileceği ve bunun ülke ekonomisine büyük katkıları olabileceği ve bu tedbirlerin zaman geçirmeden alınması gerektiğidir.

  19. Understanding the molecular mechanisms underlying the effects of light intensity on flavonoid production by RNA-seq analysis in Epimedium pseudowushanense B.L.Guo.

    Science.gov (United States)

    Pan, Junqian; Chen, Haimei; Guo, Baolin; Liu, Chang

    2017-01-01

    Epimedium pseudowushanense B.L.Guo, a light-demanding shade herb, is used in traditional medicine to increase libido and strengthen muscles and bones. The recognition of the health benefits of Epimedium has increased its market demand. However, its resource recycling rate is low and environmentally dependent. Furthermore, its natural sources are endangered, further increasing prices. Commercial culture can address resource constraints of it.Understanding the effects of environmental factors on the production of its active components would improve the technology for cultivation and germplasm conservation. Here, we studied the effects of light intensities on the flavonoid production and revealed the molecular mechanism using RNA-seq analysis. Plants were exposed to five levels of light intensity through the periods of germination to flowering, the flavonoid contents were measured using HPLC. Quantification of epimedin A, epimedin B, epimedin C, and icariin showed that the flavonoid contents varied with different light intensity levels. And the largest amount of epimedin C was produced at light intensity level 4 (I4). Next, the leaves under the treatment of three light intensity levels ("L", "M" and "H") with the largest differences in the flavonoid content, were subjected to RNA-seq analysis. Transcriptome reconstruction identified 43,657 unigenes. All unigene sequences were annotated by searching against the Nr, Gene Ontology, and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases. In total, 4008, 5260, and 3591 significant differentially expressed genes (DEGs) were identified between the groups L vs. M, M vs. H and L vs. H. Particularly, twenty-one full-length genes involved in flavonoid biosynthesis were identified. The expression levels of the flavonol synthase, chalcone synthase genes were strongly associated with light-induced flavonoid abundance with the highest expression levels found in the H group. Furthermore, 65 transcription factors, including 31

  20. Toprak Radon (222Rn Gazı Anomalilerinin ARIMA Analizi

    Directory of Open Access Journals (Sweden)

    Miraç KAMIŞLIOĞLU

    2014-12-01

    Full Text Available Özet: Zaman serileri analizi, istatistik, ekonomi, fizik ve mühendislik gibi bilim dallarında geniş uygulama alanına sahiptir. Zaman serisi analizi, değişkenlerin gelecekteki değerlerinin doğru bir şekilde tahmin edilmesi için kullanılan bir yöntemdir. Bu çalışmada, bir deprem öncüsü olarak bilinen toprak radon gazı (222Rn ölçümleri ile bir zaman serisi oluşturulmuştur. Bu veriler kullanılarak, otoregresif süreçler (ARIMA yardımıyla dinamik sistem modellemesi yapılmıştır. ARIMA; zaman serileri analizinde, zaman içerisinde rastgele gerçekleşen bir stokastik (olasılıksal sürecin veya hatalarının modellenmesidir. ARIMA modeli, temelde Box-Jenkins modeline dayanmaktadır. Box-Jenkins modeli, tek değişkenli zaman serilerinin ileriye dönük tahmin ve kontrolünde kullanılan istatistiksel tabanlı bir yöntemdir. Elde edilen sonuçlar, ARIMA modellerinin tahmin konusundaki başarısını göstermektedir. Anahtar kelimeler: Zaman Serileri Analizi, Radon Gazı (222Rn, ARIMA ARIMA Analysis of Soil Radon (222Rn Gas Anomalies Abstract: Time series analysis, has wide applications in statistics, economics, physics and engineering such disciplines. This method used for estimate correctly future values of the variables. In this study, is formed a time series with soil radon gas (222Rn measurements known as a pioneer of an earthquake. Dynamic system modelling was performed with autoregressive (ARIMA modelling process by used these measurements. ARIMA; time series analysis is modelled of the recoverable over time a random stochastic (probabilistic process or its errors. ARIMA model is based on Box-Jenkins model. Box-Jenkins model is a statistically based method which is used forward-looking forecasting and control of univariate time series. The obtained results, ARIMA model is indicating success in predict subject. Key words: Time Series Analysis, Radon Gas (222Rn, ARIMA

  1. Measurement of 8-oxo-7,8-dihydro-2'-deoxyguanosine and 8-oxo-7,8-dihydro-guanosine in cerebrospinal fluid by ultra performance liquid chromatography-tandem mass spectrometry.

    Science.gov (United States)

    Weimann, Allan; Simonsen, Anja Hviid; Poulsen, Henrik E

    2018-01-15

    Increased levels of nucleosides modified by oxidation in human cerebrospinal fluid (CSF) have several times been reported in Alzheimer patients and patients suffering from Parkinson's disease. The focus has especially been on nucleosides containing the 8-hydroxylation of guanine. Only few reports on quantification of the ribonucleoside 8-oxo-7,8-dihydro-guanosine (8oxoGuo) in CSF have been published, whereas more have been published on the quantification of the deoxy-ribonucleoside 8-oxo-7,8-dihydro-2'-deoxyguanosine (8oxodGuo). The reports on the quantification of 8oxodGuo concentrations in CSF report absolute concentrations varying by a factor >10 5 in healthy humans. This could indicate that there is a serious specificity problem in some of the methods. In this paper an isotope-dilution UPLC-MS/MS method with high specificity and sensitivity for the quantification of 8oxoGuo and 8oxodGuo in CSF is presented. LLOQ for the two analytes is determined to 4pM and 2pM, respectively. The calibration curves has been tested to be linear in the range from 4 to 3,000pM for 8oxoGuo and between 2 and 3,000pM for 8oxodGuo. Using a weighting factor of 1/x the correlation coefficient "r" for both analytes is >0.999. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Urinary albumin and 8-oxo-7,8-dihydroguanosine as markers of mortality and cardiovascular disease during 19 years after diagnosis of type 2 diabetes

    DEFF Research Database (Denmark)

    Broedbaek, Kasper; Køster-Rasmussen, Rasmus; Siersma, Volkert

    2017-01-01

    ,8-dihydroguanosine (8-oxoGuo) that represents intracellular oxidative stress. We investigated the ability of microalbuminuria (MA) and urinary 8-oxoGuo, alone and in combination, to predict mortality and cardiovascular disease (CVD) in patients with type 2 diabetes. We used data from 1381 newly diagnosed diabetes...... patients, and urinary albumin and 8-oxoGuo were assessed in morning urine collected at the time of diabetes diagnosis and at a follow-up visit 6 years later. Associations between the urinary markers and mortality and CVD were assessed in Cox proportional hazards regression models. Test performance......-up. At diagnosis only urinary albumin was associated with CVD. In contrast, only 8-oxoGuo was associated with CVD at 6-year follow-up. When investigating test performance, we found that by combining information from MA and 8-oxoGuo the ability to correctly identify patients at risk could be improved. The findings...

  3. Understanding the molecular mechanisms underlying the effects of light intensity on flavonoid production by RNA-seq analysis in Epimedium pseudowushanense B.L.Guo.

    Directory of Open Access Journals (Sweden)

    Junqian Pan

    Full Text Available Epimedium pseudowushanense B.L.Guo, a light-demanding shade herb, is used in traditional medicine to increase libido and strengthen muscles and bones. The recognition of the health benefits of Epimedium has increased its market demand. However, its resource recycling rate is low and environmentally dependent. Furthermore, its natural sources are endangered, further increasing prices. Commercial culture can address resource constraints of it.Understanding the effects of environmental factors on the production of its active components would improve the technology for cultivation and germplasm conservation. Here, we studied the effects of light intensities on the flavonoid production and revealed the molecular mechanism using RNA-seq analysis. Plants were exposed to five levels of light intensity through the periods of germination to flowering, the flavonoid contents were measured using HPLC. Quantification of epimedin A, epimedin B, epimedin C, and icariin showed that the flavonoid contents varied with different light intensity levels. And the largest amount of epimedin C was produced at light intensity level 4 (I4. Next, the leaves under the treatment of three light intensity levels ("L", "M" and "H" with the largest differences in the flavonoid content, were subjected to RNA-seq analysis. Transcriptome reconstruction identified 43,657 unigenes. All unigene sequences were annotated by searching against the Nr, Gene Ontology, and Kyoto Encyclopedia of Genes and Genomes (KEGG databases. In total, 4008, 5260, and 3591 significant differentially expressed genes (DEGs were identified between the groups L vs. M, M vs. H and L vs. H. Particularly, twenty-one full-length genes involved in flavonoid biosynthesis were identified. The expression levels of the flavonol synthase, chalcone synthase genes were strongly associated with light-induced flavonoid abundance with the highest expression levels found in the H group. Furthermore, 65 transcription factors

  4. Okul Öncesi Öğretmenliği Lisans Programında Yer Alan Drama Dersi Kapsamında Yapılan Uygulamaların Öğretmen Adaylarının Sosyal Zekâ Alanlarına Etkisi

    OpenAIRE

    Ünver, Naim; Semiz, Selahattin

    2016-01-01

    Eğitim fakülteleri lisans programları, değişen dünya ve toplumların ihtiyaçlarına göreMEB’in amaçları da dikkate alınarak zaman zaman değişmekte ve geliştirilmektedir. Fakatözellikle bazı dersler ve içerik, bütün programlarda yer alması gereken, zamandan veihtiyaçlardan etkilenmeyen, doğrudan ve her zaman çocukların temel gelişimlerini destekleyenözellikler taşıdığı için, bütün programlarda yer almaktadır. Okul öncesi eğitimi lisansprogramındaki dersler içerisinde yer alan Drama dersi de çocu...

  5. Development and validation of a 2nd tier test for identification of purine nucleoside phosphorylase deficiency patients during expanded newborn screening by liquid chromatography-tandem mass spectrometry.

    Science.gov (United States)

    la Marca, Giancarlo; Giocaliere, Elisa; Malvagia, Sabrina; Villanelli, Fabio; Funghini, Silvia; Ombrone, Daniela; Della Bona, Maria; Forni, Giulia; Canessa, Clementina; Ricci, Silvia; Romano, Francesca; Guerrini, Renzo; Resti, Massimo; Azzari, Chiara

    2016-04-01

    Purine nucleoside phosphorylase (PNP) deficiency has been recently introduced in the newborn screening program in Tuscany. In order to improve the PNP screening efficiency, we developed a 2nd tier test to quantify PNP primary markers deoxyguanosine (dGuo) and deoxyinosine (dIno). Dried blood spots (DBS) samples were extracted with 200 μL of methanol and 100 μL of water (by two steps). Internal standards were added at a final concentration of 10 μmol/L. After extraction, samples were analysed by LC-MS/MS. The chromatographic run was performed in gradient mode by using a Synergi Fusion column. The assay was linear over a concentration range of 0.05-50 μmol/L (R2>0.999) for dGuo and 0.5-50 μmol/L (R2>0.998) for dIno. Intra- and interassay imprecision (mean CVs) for dIno and dGuo ranged from 2.9% to 12%. Limit of quantitaion (LOQ) were found to be 0.05 μmol/L and 0.5 μmol/L for dGuo and dIno, respectively. The reference ranges, obtained by measuring dGuo and dIno concentrations on DBS, were close to zero for both biomarkers. Moreover, DBS samples from seven patients with confirmed PNP were retrospectively evaluated and correctly identified. The LC-MS/MS method can reliably measure dIno and dGuo in DBS for the diagnosis of PNP. Validation data confirm the present method is characterised by good reproducibility, accuracy and imprecision for the quantitation of dIno and dGuo. The assay also appears suitable for use in monitoring treatment of PNP patients.

  6. Hiina kunstnikud kaebavad Veneetsia biennaali kohtusse / Maria-Kristiina Soomre

    Index Scriptorium Estoniae

    Soomre, Maria-Kristiina, 1978-

    2000-01-01

    1999. a. Veneetsia biennaalil auhinna võitnud hiina kunstniku Cai Guo Qiangi teos "Veneetsia maksukoguja hoov" on Hiinas tekitanud diskussiooni autoriõiguste teemal. Kaalutakse kohtuasja algatamist Cai Guo Qiangi, Harald Szeemanni ja Veneetsia biennaali vastu

  7. Osmanlı Devleti’nin Kuruluş Döneminde Meşruiyet Sorunu ve İlk Kaynaklara Yansıması

    OpenAIRE

    CİDE, Ömer

    2015-01-01

    Her toplumun kendine ait değerleri vardır. Bu değerler, dinamik bir yapıya sahip olan insanın ürünü olduğu için sürekli değişim hâlindedir. Bundan ötürü oluşturulan değerler zaman içerisinde farklılık arz edebilir. İnsanların meydana getirdikleri en büyük teşkilatlardan birisi de devlettir. Ayrı zaman ve mekânlarda birçok devlet kurulmuştur. Devlete, kurulmuş olduğu dönemin geçerli olan değerlerine göre felsefî bir anlam yüklenmiştir. Bu, geçmişle sınırlı olmayıp yaşadığımız zaman diliminde d...

  8. High-affinity monoclonal antibodies specific for deoxynucleosides structurally modified by alkylating agents: Applications for immunoanalysis

    International Nuclear Information System (INIS)

    Adamkiewicz, J.; Ahrens, O.; Rajewsky, M.F.

    1984-01-01

    So far the results of attempts to use monoclonal antibodies for the demonstration of carcinogen-DNA adducts in cells by immunostaining have been promising. Thus the authors have established a standardized procedure for the quantitation of specific alkyl-deoxynucleosides in the nuclear DNA of individual cells by direct immunofluorescence, using tetramethylrhodamine isothiocyanate-labeled monoclonal antibodies and a computer-based image analysis of electronically intensified fluorescence signals. With a fluorescent anti-(O/sup 6/-EtdGuo) monoclonal antibody, the present detection limit for O/sup 6/-Etd-Guo in the nuclei of individual cells previously exposed to an ethylating N-nitroso compound (e.g., N-ethyl-N-nitrosourea) is -- 700 O/sup 6/-EtdGuo molecules per diploid genome, i.e., similar to the detection limit for the same ethylation product in a hydrolysate of (O/sup 6/-EtdGuo)-containing DNA analyzed by competitive RIA

  9. Reference: 378 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 378 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u16640597i Guo Yongfeng... family transcription factor, has an important role in leaf senescence. 4 601-12 16640597 2006 May The Plant journal Gan Susheng|Guo Yongfeng

  10. Taxol synthesis | Guo | African Journal of Biotechnology

    African Journals Online (AJOL)

    Being a complex diterpenoid, the potent anticancer drug, Taxol, requires complicated steps for its biosynthesis. In the present article, recent advances on Taxol biosynthesis pathway are reviewed, including many recently reported genes that regulate Taxol biosynthesis. To meet the urgent need of clinic and scientific ...

  11. Measurement of 8-oxo-7,8-dihydro-2'-deoxyguanosine and 8-oxo-7,8-dihydro-guanosine in cerebrospinal fluid by ultra performance liquid chromatography-tandem mass spectrometry

    DEFF Research Database (Denmark)

    Weimann, Allan; Simonsen, Anja Hviid; Poulsen, Henrik E

    2018-01-01

    absolute concentrations varying by a factor >105 in healthy humans. This could indicate that there is a serious specificity problem in some of the methods. In this paper an isotope-dilution UPLC-MS/MS method with high specificity and sensitivity for the quantification of 8oxoGuo and 8oxodGuo in CSF...

  12. Lipocalin 2: a "sexy" adipokine that regulates 17Beta-estradiol and obesity

    Science.gov (United States)

    In this article we review the findings of Guo et. al. (Endocrinology, 153: 1183-1193) that the protein, Lipocalin 2 is more highly expressed in subcutaneous adipose tissue than in gondal tissue of female mice. Of particular interest is that the paper by Guo et. al. observed that ablation of the Lip...

  13. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. Lingchen Guo. Articles written in Journal of Genetics. Volume 81 Issue 1 April 2002 pp 13-17 Perspectives. Cloning, chromosome localization and features of a novel human gene, MATH2 · Lingchen Guo Min Jiang Yushu Ma Haipeng Cheng Xiaohua Ni Yangsheng Jin Yi Xie Yumin ...

  14. TRAVEL TO TIME: CLOCK AND CLOCK TYPES IN DIVAN POETRY ZAMANA YOLCULUK: DİVAN ŞİİRİNDE SAAT VE SAAT ÇEŞİTLERİ

    Directory of Open Access Journals (Sweden)

    Gülay DURMAZ

    2012-06-01

    Full Text Available Measuring time has always been essential for humans. Until we had the modern day clocks, various techniques had been used, and time had been tried to be regulated. During this process many different types of clocks emerged. In this article, reflection of clock and its progress in the real world on the Divan poetry will be examined. Couplets revealing how the topic of clocks and time was held in the trips to the imaginations of the Divan poet will lead the way in this examination Zamanı ölçmek, insanoğlu için her zaman çok önemli olmuştur. Bugün kullandığımız saatlere ulaşıncaya kadar, pek çok yöntem denenmiş ve zamanın düzenlenmesine çalışılmıştır. Bu aşamada birçok saat çeşidi de ortaya çıkmıştır. Bu makalede saatin ve saat çeşitlerinin gerçek dünyadaki gelişiminin Divan şiirine yansıması izlenmeye çalışılacaktır. Bunun için Divan şairinin, hayal dünyasının yolculuğunda saat ve zaman konusuna nasıl yer verdiğini gösteren beyitler, bu konudaki yol göstericiler olacaktır.

  15. Novel application of sugar-borate complexation for separation of ribo-2'-deoxyribo-, and arabinonucleosides on cation-exchange resin

    Energy Technology Data Exchange (ETDEWEB)

    Pal, B C

    1978-01-01

    Separation of the three groups of nucleosides: (1) Urd, ara-Urd, and dUrd; (2) Cyd, ana-Cyd, and dCyd; (3) Ado, ara-Ado, and dAdo are shown in graphs. There is a slight overlap between the ara-Urd and dUrd peaks. Separation of the group of nucleosides, Guo, ara-Guo, and dGuo was not studied because ara-Guo was not available. In all three cases, ribonucleosides were eluted first, followed by arabinonucleosides and deoxyribonucleosides. This is in accord with our concept of stability and formation of borate complexes. In ribonucleosides (I) the 2'- and 3'-hydroxyl groups are in the cis position, which facilitates the formation of a borate complex, whereas in arabinonucleosides (II) the 2'- and 3'-hydroxyl groups are in the trans position and complex less well with borate. The 2'-deoxyribonucleosides (III) lack vicinal hydroxyl groups and hence do not form borate complexes at all. The anions are excluded according to the amount of negative charge carried by them as a result of borate complexation. The order of elution is ribonucleosides, arabinonucleosides, and deoxyribonucleosides.

  16. Case series

    African Journals Online (AJOL)

    abp

    1 juin 2012 ... ... Ren- Xuan Guo, and Ke-Jian Guo. Adult intussusception: A retrospective review of 41 cases. World J Gastroenterol. 2009 Jul 14;15(26):3303-8. This article on PubMed. 14. Abou-Nukta F, Gutweiler J, Khaw J, Yavorek G. Giant lipoma causing a colo-colonic intussusception. Am Surg. 2007;73(4):417. This.

  17. Acquisition of resistance to 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride in V79 cells through increased removal of O6-alkylguanine.

    Science.gov (United States)

    Satoh, M S; Huh, N H; Horie, Y; Thomale, J; Rajewsky, M F; Kuroki, T

    1987-10-01

    The molecular mechanism of acquisition of resistance to 1-(4-amino-2-methyl-5-pyrimidinyl)-methyl-3-(2-chloroethyl)-3-nitroso ure a hydrochloride (ACNU) was investigated using ACNU-resistant clones (ACNUr-1-4) isolated from the V79 cell line. The binding level of alkyl cyanate, a decomposition product of ACNU, to protein in ACNUr-1 cells was not less than that in the parental V79 cells, indicating that the acquired resistance was not due to a reduced intracellular concentration of ACNU. Because O6-chloroethylguanine, an intermediate in cytotoxic interstrand cross-link formation by ACNU, is known to be repaired by the same mechanism as O6-ethyldeoxyguanosine (O6-EtdGuo), we quantitated O6-EtdGuo by radioimmunoassay at various times after exposure of cells to 100 micrograms/ml N-ethyl-N-nitrosourea for 20 min. In V79 cells, elimination of O6-EtdGuo was negligible, but in all four resistant clones, 30 to 59% of the O6-EtdGuo was removed within 24 hr after exposure. This increased removal of O6-EtdGuo among the resistant clones was associated with the activity of O6-alkylguanine DNA alkyltransferase (O6-AGT) determined using cell extracts. The present results indicate that increased removal of O6-chloroethylguanine in ACNU-resistant clones by O6-AGT is mechanistically linked to the acquisition of resistance to ACNU.

  18. Invention Zaman Barok dan Pengembangan Permainan Piano

    Directory of Open Access Journals (Sweden)

    RIANTI MARDALENA PASARIBU

    2013-11-01

    Full Text Available Invention in Barok Era and The Development of Piano Lesson. In piano lesson, one material of parts towhich had been given is polyphony, which is an Invention from J.S. Invention is a basic fi nger-skill for pianist.Invention develops in the Baroque period. The baroque ideology is not only called as the reaction of Renaissance,but also as the continuing development from Renaissance. Invention is known in two forms. First is as a pianocomposition and second is as a piano play which can push a pianist to understand more about an arrangement thathe played and expressed.

  19. Browse Title Index

    African Journals Online (AJOL)

    Items 7351 - 7400 of 11090 ... Vol 10, No 65 (2011), Molecular cloning and sequence analysis of VP6 gene of giant panda rotavirus strain CH-1, Abstract PDF. Y Lie, S Chen, CD Wang, Z Zhang, CD Wang, W Guo, X Wang, L Guo, Q Yan. Vol 11, No 23 (2012), Molecular cloning, characterization and expression analysis of heat ...

  20. Increased incidence of transient homogeneous immunoglobulins in irradiated and reconstituted C57BL/KaLwRij mice treated with 2'-deoxyguanosine

    International Nuclear Information System (INIS)

    Akker, Th.W. van den; Gillen, A.P.; Bril, H.; Brenner, R.; Radl, J.

    1983-01-01

    Prolonged administration of micromolar amounts of 2'-deoxyguanosine (dGuo) to lethally irradiated and reconstituted mice led to an increased incidence of transient homogeneous immunoglobulins (H-Ig) in their sera. Analysis of the heavy and light chain isotype distribution among the H-Ig revealed more of the IgG2b and IgG3 isotypes and less of the IgM isotype and the lambda light chain containing H-Ig in the dGuo-treated group as compared to the control group. The increased incidence of H-Ig was preceded by a decreased suppressor T cell generation and activation in the dGuo treated group. These data indicate that deficient suppressor T cell plays an important role in the development of transient H-Ig. (author)

  1. Ultrasonik Homojenizasyon İşleminin Yoğurdun Su Tutma Kapasitesi Üzerine Etkisi

    Directory of Open Access Journals (Sweden)

    Mustafa Şengül

    2015-02-01

    Full Text Available Çalışmada, ısıl olmayan muhafaza tekniklerinden biri olan ultrason ve klasik homojenizatör kullanılarak homojenize edilen sütlerden elde edilen yoğurtların su tutma kapasiteleri incelenmiştir. Ultrasonik homojenizasyonda, 20, 50 ve %70 olmak üzere 3 farklı güç seviyesi, 3 ve 6 dakika olmak üzere 2 farklı işlem zamanı kullanılmıştır. Klasik homojenizasyonla karşılaştırıldığında, ultrasonik homojenizasyonun yoğurdun su tutma kapasitesi üzerine daha etkili olduğu belirlenmiştir. İşlem zamanı ve güç seviyesi arttıkça su tutma kapasitesi de artmıştır. En yüksek su tutma kapasitesi (%66.18, 6 dakikalık işlem zamanı ve %70 güç seviyesinde elde edilmiştir. Ayrıca, fermantasyon boyunca örneklerin pH değerleri 30’ar dakikalık periyotlarla izlenmiştir.

  2. Patent havuzlarının rekabet açısından değerlendirilmesi

    OpenAIRE

    SEMERCİ, AYBÜKE

    2010-01-01

    Patent havuzları, genellikle benzer pazarda patent sahibi olan rakipler tarafından kurulmaktadır. Patent hakkı sahipleri fikri haklarını patent havuzunda toplamakta ve üçüncü şahıslara ve/veya kendilerine bu havuzu lisans vermektedir. Rakip firmalar kimi zaman birbirlerine karşı açtıkları agresif patent davalarından daha fazla zarar görmemek için, kimi zaman lisans ödemeleri gereken çok fazla firma olduğunda işlem maliyetlerini azaltma için patent havuzuna başvurmaktadırlar. Geçmişte bazı pat...

  3. Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans

    DEFF Research Database (Denmark)

    Larsen, Emil List; Cejvanovic, Vanja; Kjaer, Laura Kofoed

    2017-01-01

    , phenoxymethylpenicillin (penicillin V), or placebo. Oxidative modifications were measured as 24-h urinary excretion of 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) and 8-oxo-7,8-dihydroguanosine (8-oxoGuo), and plasma levels of malondialdehyde before and after treatment as a measurement of DNA oxidation, RNA oxidation.......7% (95% CI: 5.8–37.6%), but did not influence urinary excretion of 8-oxoGuo. Penicillin V did not influence urinary excretion of 8-oxodG or 8-oxoGuo. None of the antibiotic drugs influenced plasma levels of malondialdehyde. Conclusion Clarithromycin significantly increases oxidative nucleic acid...... modifications. Increased oxidative modifications might explain some of clarithromycin's known adverse reactions. Trimethoprim significantly lowers DNA oxidation but not RNA oxidation. Penicillin V had no effect on oxidative nucleic acid modifications....

  4. Bıldırcın ve Ördek Yumurtalarında Maya-Küf ve Total Bakteri Açısından İncelenmesi

    Directory of Open Access Journals (Sweden)

    Işın Var

    2015-02-01

    Full Text Available Bıldırcın yumurtası, besin değeri yönünden tavuk yumurtasından oransal olarak daha zengin kabul edilmektedir. Daha çok salata, pasta, mayonez vb. yapımında yaygın olarak kullanılan ördek yumurtası (Pekin ördeği tavuk yumurtasına göre daha büyük olup, ağırlıkları 70-90 g arasında değişmektedir. Bıldırcın yumurtası son yıllarda özellikle küçük çocuk ve yaşlı beslenmesinde önem kazanmıştır. Bunun yanısıra bazı hastalıkların tedavisi amacıyla da halk arasında oldukça yaygın kullanılmaktadır. Özellikle çiğ olarak tüketilen bıldırcın yumurtaları zaman zaman içerdikleri patojen mikroorganizmalarla tehlikeli olabilmektedirler. Bu çalışmada bıldırcın ve ördek yumurtalarında maya-küf ve total bakteri aranmıştır. Bıldırcın ve ördek yumurtalarının özellikle kabuğunda hem total bakteri hem de maya-küf bulunmuştur. Bıldırcın yumurtasının akı ve sarısında ise zaman zaman kontaminasyonla karşılaşılmıştır.

  5. Thidiazuron: A multi-dimensional plant growth regulator | Guo ...

    African Journals Online (AJOL)

    Thidiazuron (TDZ) has gained a considerable attention during past decades due to its efficient role in plant cell and tissue culture. Wide array of physiological responses were observed in response to TDZapplication in different plant species. TDZ has shown both auxin and cytokinin like effects, although, chemically, it is ...

  6. Inventarisasi Cerita Rakyat Dari Kabupaten Demak Melalui Aplikasi Buku Digital (E-Book Interaktif

    Directory of Open Access Journals (Sweden)

    Noor Hasyim

    2015-08-01

    Full Text Available Cerita rakyat merupakan salah satu keunikan budaya yang dimiliki oleh setiap daerah, termasuk daerah Kabupaten Demak. Cerita rakyat mampu menjadi sarana pendidikan nilai-nilai luhur yang diwariskan oleh pendahulu kepada generasi mendatang. Inventarisasi cerita rakyat ini penting dilakukan seiring modernisasi yang terjadi di segala bidang menjadikan masyarakat setempat khususnya generasi muda banyak yang tidak mengetahui cerita tersebut. Di zaman modern inventarisasi harus juga dilakukan denga cara modern pula. Salah satu caara untuk mengemas cerita rakyat di zaman modern adalah menggunakan aplikasi buku digital yang dibuat interaktif. Perkembangan komputer tablet berbasis touchscreen semakin menambah interaktif gambar bergerak yang disajikan di dalam aplikasi buku digital. Kata Kunci: Buku digital, Cerita Rakyat, E-book, Folklor

  7. A Review on Gnetalean Megafossils: Problems and Perspectives

    Directory of Open Access Journals (Sweden)

    Yong Yang

    2010-11-01

    Full Text Available Gnetalean megafossils were accumulated in the last decade. Taxonomic positions of several of Ephedran megafossil species are, however, controversial, resulting in a complicated nomenclature. Liaoxia Z.Y. Cao & S.Q. Wu, “Eragrostis Z.Y. Cao & S.Q. Wu”, “Chaoyangia Duan”, and their type species “Liaoxia cheniae Z.Y. Cao & S.Q. Wu”, “Eragrostis changii Z.Y. Cao & S.Q. Wu”, “Chaoyangia liangii S.Y. Duan”, were not validly published in the original publication under the Vienna Code. The species “Liaoxia cheniae Z.Y. Cao & S.Q. Wu” was validly published as Ephedrites cheniae S.X. Guo & X.W. Wu but later combined into Liaoxia cheniae (S.X. Guo & X.W. Wu Z.Y. Cao & S.Q. Wu and further into Ephedra cheniae (S.X. Guo & X.W. Wu H.M. Liu et al. Some uncertain morphological characters are fundamental to elucidate the taxonomic position of Ephedrites cheniae S.X. Guo & X.W. Wu and “Chaoyangia liangii S.Y. Duan”, e.g. bract number, position, and connation in female cones, seed number and position in a female cone, and morphology of the furcated appendages of reproductive organs of “Chaoyangia liangii S.Y. Duan”.

  8. Problem of quantifying quantum correlations with non-commutative discord

    Science.gov (United States)

    Majtey, A. P.; Bussandri, D. G.; Osán, T. M.; Lamberti, P. W.; Valdés-Hernández, A.

    2017-09-01

    In this work we analyze a non-commutativity measure of quantum correlations recently proposed by Guo (Sci Rep 6:25241, 2016). By resorting to a systematic survey of a two-qubit system, we detected an undesirable behavior of such a measure related to its representation-dependence. In the case of pure states, this dependence manifests as a non-satisfactory entanglement measure whenever a representation other than the Schmidt's is used. In order to avoid this basis-dependence feature, we argue that a minimization procedure over the set of all possible representations of the quantum state is required. In the case of pure states, this minimization can be analytically performed and the optimal basis turns out to be that of Schmidt's. In addition, the resulting measure inherits the main properties of Guo's measure and, unlike the latter, it reduces to a legitimate entanglement measure in the case of pure states. Some examples involving general mixed states are also analyzed considering such an optimization. The results show that, in most cases of interest, the use of Guo's measure can result in an overestimation of quantum correlations. However, since Guo's measure has the advantage of being easily computable, it might be used as a qualitative estimator of the presence of quantum correlations.

  9. Targeting MED1 LxxLL Motifs for Tissue-Selective Treatment of Human Breast Cancer

    Science.gov (United States)

    2014-09-01

    microRNA, antisense oligonucleotides, and RNA aptamers, has long been extensively studied (Guo 2010; Keefe et al. 2010; Levy-Nissenbaum et al. 2008; Que...targeted drug delivery when compared with DNA aptamers, protein aptamers, and antibodies (Guo 2010; Keefe et al. 2010; Que-Gewirth and Sullenger...or even organisms (Dua et al. 2011; Keefe et al. 2010; Levy-Nissenbaum et al. 2008; Thiel and Giangrande 2010). Those that do not bind to the target

  10. DNA radio-induced tandem lesions: formation, introduction in oligonucleotides and repair

    International Nuclear Information System (INIS)

    Bourdat, Anne-Gaelle

    2000-01-01

    Cell killing induced by excited photosensitizers, ionizing radiation or radiomimetic drugs can not be only explained by the formation of single DNA lesions. Thus, multiply damaged sites, are likely to have harmful biological consequences. One example of tandem base damage induced by ".OH radical in X-irradiated aqueous solution of DNA oligomers is N-(2-deoxy-β-D-erythro-pentofuranosyl)-formyl-amine (dβF)/8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo). In order to investigate the biological significance of such a tandem lesion, both 8-oxodGuo and dβF were introduced in synthetic oligonucleotides at vicinal positions using the solid phase phosphoramidite method with the 'Pac phosphoramidite' chemistry. The purity of the synthetic DNA fragments and the integrity of modified nucleosides was confirmed using different complementary techniques: HPLC, PAGE, ESI MS, MALDI-TOF MS and capillary electrophoresis. Using the above synthetic substrates, investigations were carried out in order to determine the substrate specificity and the excision mechanism of three glycosylases involved in the base excision repair pathway: endonuclease III, Fpg and yOggl. Both tandem lesions were substrates for the BER enzymes. However, the tandem lesion are not completely excised by the repair enzymes. The rates of excision as inferred from the determination of the ratios of Vm/Km Michaelis kinetics constants were not found to be significantly affected by the presence of the tandem lesions. MALDI-TOF mass spectrometry was used in order to gain insights into mechanistic aspects of oligonucleotide cleavage by the BER enzymes. During in vitro DNA synthesis by Taq DNA polymerase, Klenow fragment exo- and DNA polymerase β, tandem base damage were found to block the progression of the enzymes. Finally, the level of tandem base damage in the DNA exposed to γ-ray using the liquid chromatography coupled to electro-spray ionization tandem mass spectrometry was determined. Both dβF-8-oxodGuo and 8

  11. Myometrial invasion and overall staging of endometrial carcinoma: assessment using fusion of T2-weighted magnetic resonance imaging and diffusion-weighted magnetic resonance imaging

    OpenAIRE

    Guo, Yu; Wang, Ping; Wang, Penghui; Gao, Wei; Li, Fenge; Yang, Xueling; Ni, Hongyan; Shen, Wen; Guo, Zhi

    2017-01-01

    Yu Guo,1,2 Ping Wang,2 Penghui Wang,2 Wei Gao,1 Fenge Li,3 Xueling Yang,1 Hongyan Ni,2 Wen Shen,2 Zhi Guo1 1Department of Interventional Therapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin, 2Department of Radiology, Tianjin First Center Hospital, The First Central Clinical College of Tianjin Medical University,...

  12. Association Between Urinary Markers of Nucleic Acid Oxidation and Mortality in Type 2 Diabetes

    DEFF Research Database (Denmark)

    Broedbaek, Kasper; Siersma, Volkert Dirk; Henriksen, Trine Maxel

    2013-01-01

    years after the diagnosis to assess the association between urinary markers of nucleic acid oxidation and mortality in patients with established and treated diabetes.RESEARCH DESIGN AND METHODSWe used data from the 970 patients who attended the screening for diabetes complications 6 years after...... the diagnosis. Cox proportional hazards regression was used to examine the relationship between urinary markers of DNA oxidation (8-oxo-7,8-dihydro-2'-deoxyguanosine [8-oxodG] [n = 938]) and RNA oxidation (8-oxoGuo [n = 936]) and mortality.RESULTSDuring a median of 9.8 years of follow-up, 654 patients died....... Urinary 8-oxoGuo assessed 6 years after the diagnosis was significantly associated with mortality. The multivariate-adjusted hazard ratios for all-cause and diabetes-related mortality of patients with 8-oxoGuo levels in the highest quartile compared with those in the lowest quartile were 1.86 (95% CI 1...

  13. Lycopene and ß-carotene protect in vivo iron-induced oxidative stress damage in rat prostate

    Directory of Open Access Journals (Sweden)

    H.R. Matos

    2006-02-01

    Full Text Available It has been suggested that iron overload may be carcinogenic. In the present study, we evaluated the effect of plasma and prostate carotenoid concentration on oxidative DNA damage in 12-week-old Wistar rats treated with intraperitoneal (ip ferric nitrilotriacetate (Fe-NTA (10 mg Fe/kg. Plasma ß-carotene and lycopene concentrations were measured as a function of time after ip injection of carotenoids (10 mg kg-1 day-1 ß-carotene or lycopene in rats. The highest total plasma concentration was reached 3 and 6 h after ip injection of lycopene or ß-carotene, respectively. After 5 days of carotenoid treatment, lycopene and ß-carotene were present in the 0.10-0.51 nmol/g wet tissue range in the prostate. Using a sensitive method to detected 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo by HPLC/EC, the level of 8-oxodGuo in rat prostate DNA was significantly higher (6.3 ± 0.6 residues/10(6 dGuo 3 h after Fe-NTA injection compared with control rats (1.7 ± 0.3 residues/10(6 dGuo. Rats supplemented with lycopene or ß-carotene for 5 days prior to Fe-NTA treatment showed a reduction of about 70% in 8-oxodGuo levels to almost control levels. Compared with control rats, the prostate of Fe-NTA-treated animals showed a 78% increase in malondialdehyde accumulation. Lycopene or ß-carotene pre-treatment almost completely prevented lipid damage. Epidemiological studies have suggested a lower risk of prostate cancer in men reporting a higher consumption of tomato products. However, before associating this effect with tomato sauce constituents, more information is required. The results described here may contribute to the understanding of the protective effects of carotenoids against iron-induced oxidative stress.

  14. Ultrastructural study of the development of Sarcocystis singaporensis sarcocysts in the muscles of its rat host

    Directory of Open Access Journals (Sweden)

    Paperna I.

    2002-06-01

    Full Text Available Laboratory rats fed sporocysts of Sarcocystis singaporensis (Zaman & Colley, 1975 Zaman & Colley, 1976 originating from Singapore were euthanized 22, 23, 33 and 80 days later. Sporocysts were extracted from feces of either naturally or laboratory-infected Python reticulatus. Electron microscopically examined tongue and esophageal muscles yielded images of successive developing stages of sarcocysts. The primary wall evolved from a continuous thin layer into folds and later, into villar protrusions. At all stages the wall was interrupted by pinocytotic-like indentations. Young sarcocysts contained only metrocytes, they divided by endodyogeny into daughter metrocytes. The first bradyzoites appeared only 33 d.p.i. Sarcocysts by 80 d.p.i. were enclosed in a fully differentiated primary wall and contained almost entirely bradyzoites.

  15. Mircea Eliade'de "Kutsal ve Kutsal Zaman" Kavrami

    Directory of Open Access Journals (Sweden)

    Münir Yıldırım

    2015-11-01

    Full Text Available In common, sacred is defined with the word of religion. Also religion is often defined in terms of sacred as distinc from the profane. In a wider sense, the notion of the sacred has been identified, to some extent, with that of religious. Mircea Eliade points out, the sacred is revealed in the profane and anything that humans have ever handled come intact with or loved can reveal the sacred. According to Eliade, all definitions that have ever been give of the religious phenomenon make the sacred the opposite of the profane. Meanwhile, the sacred as that was awesome and reducible to reason. On the other way, there is another notion that as with sacred, is that sacred time. It’s a time that essentially different from the profane time. According to Eliade time divided into the “sacred” and “profane” times, sacred time differ from profane but this latter reckoning itself differs in nature

  16. MIKRO-IŞLEMCI DESTEKLİ ZAMAN SIRALI PATLATMA UYGULAMALARI

    OpenAIRE

    KUZU, Cengiz

    1998-01-01

    Günümüzdeki teknolojik gelişmeler, mikro elektroniğin hemen hemen tüm endüstriyel uygulamaların içine girmesi sonucunu doğurmuştur. Patlatma çalışmalarında da, bu yönde örnekler görmek mümkündür. Patlatma uygulamalarındaki mikro işlemcilerin bulunduğu yerler, klasik elektrikli gecikmeli kapsüller veya elektronik kapsüller kullanılmasına göre farklılıklar göstermektedir. Bunlardan ilkinde, mikro işlemciler patlatma devresi elemanlarına ve ikincisinde, kapsüllerin içine ve patlatma devresi elem...

  17. Oxidative damage to guanine nucleosides following combination chemotherapy with 5-fluorouracil and oxaliplatin

    DEFF Research Database (Denmark)

    Afzal, Shoaib; Jensen, Søren Astrup; Sørensen, Jens Benn

    2011-01-01

    PURPOSE: Recent in vitro and animal studies have suggested that the cytotoxicity of 5-fluorouracil and oxaliplatin is linked to increased formation of reactive oxygen species (ROS). This prospective study was undertaken to examine the generation of oxidative stress, in 106 colorectal cancer patie...... concentrations of 8-oxoGuo and 8-oxodG and the treatment effect and the other variables. RESULTS: The analysis showed that chemotherapy increased the excretion of 8-oxoGuo and 8-oxodG around 15% (P ...

  18. McCarthy's The Road and Ethical Choice in a Post-Apocalyptic World

    OpenAIRE

    Guo, Jingjing

    2015-01-01

    In her article "McCarthy's The Road and Ethical Choice in a Post-Apocalyptic World" Jingjing Guo analyses ethical choice and its implications in McCarthy's The Road. After examining the deterioration of the ethical context and the prevalence of evil reflected in cannibalism, Guo highlights the father's ethical choice and dilemma. Different from most others, the father chooses to keep alive to protect his son, and to stay man and stay good in a physically devastated and morally bankrupted worl...

  19. Enzymatic removal of O6-ethylguanine from mitochondrial DNA in rat tissues exposed to N-ethyl-N-nitrosourea in vivo

    International Nuclear Information System (INIS)

    Satoh, M.S.; Huh, N.; Rajewsky, M.F.; Kuroki, T.

    1988-01-01

    DNA repair is essential for maintaining the integrity of the genetic material, and a number of DNA repair mechanisms have been fairly well characterized for the nuclear DNA of eukaryotic cells as well as prokaryotes. However, little is know about DNA repair in mitochondria. Using highly sensitive immunoanalytical methods to detect specific DNA alkylation products, the authors found active removal of O 6 -ethyl-2'-deoxyguanosine (O 6 -EtdGuo) from rat liver mitochondrial DNA after pulse-exposure to N-ethyl-N-nitrosourea in vivo. In the kidney, O 6 -EtdGuo was removed from mitochondrial DNA with moderate efficiency, but nearly no removal was observed from the DNA of brain mitochondria. Among the rat tissues examined, the kinetics of O 6 -EtdGuo elimination from mitochondrial DNA was very similar to the kinetics of removal from nuclear DNA. O 4 -Ethyl-2'-deoxythymidine, another premutagenic DNA ethylation product, was stable in both mitochondrial and nuclear DNA of rat liver

  20. Konut Transformasyonu Bağlamında Lefke’deki CMC Evlerinin Zaman İçerisindeki Dönüşümü / The Gradual Transformation of CMC Houses in Lefke within the Context of Housing Transformation

    Directory of Open Access Journals (Sweden)

    Çağla Beyaz

    2017-06-01

    Full Text Available Abstract This study aims to determine the reflections of the factors affecting the gradual change of the houses constructed for the American mining company CMC (Cyprus Mines Corporation in Lefke between 1916 and 1974. Research has shown that such factors as life standards, needs, politics, environmental factors, climate, geography and cultural factors have changed the housing demand. Having taken all these factors into consideration, we have reached a conclusion regarding the transformation of the houses by analysing the collected data by field research techniques appropriate to CMC houses in Lefke. The field research has been conducted by taking samples from each category and analysing them; and the gradual transformation and the underlying environmental factors have been determined. The field research techniques used in the study are interviews, photos, relieves and archive research. In the result obtained from the general work; Along with the rapid development caused by the effects of the Industrial Revolution, religious, cultural, economical, political and architectural conditions have been shaped in different forms and values. Along with these circumstances, the changes and transformations that observed in the world and affecting the cities have also affected Cyprus Island. In the Lefke region, along with the establishment of the CMC, the positive and negative effects of the terraced houses, built for the first time in Cyprus in four different categories and their close surroundings, draw quite attention. In the study, the transformations of these houses until today and the factors affecting them have been also determined. Öz Çalışma, Lefke Bölgesinde 1916-1974 yılları arasında faaliyet gösteren Amerikan maden şirketi CMC (Cyprus Mines Corporation için yapılmış olan konutların zaman içerisindeki form değişimine etki eden faktörlerin, konut mekânına olan etkilerini saptamaya yöneliktir. Konut ihtiyacının, yaşam

  1. BAZI PSİKANALİSTLERE GÖRE RÜYANIN İNSAN HAYATINDAKİ ROLÜ

    Directory of Open Access Journals (Sweden)

    Abdulvahit İMAMOĞLU

    2010-04-01

    Full Text Available Rüya, insan hayatında daima var olan psikolojik bir fenomendir. İnsanın iç dünyasını belli sem-bol ve kendine has anlatımlarla yansıtmaktadır. Ayrıca, fertlerin günlük yaşantısına zaman zaman yön vermekte ya da dolaylı olarak fertleri etkilemiş olmaktadır. Bu çalışmada, rüyaların insanın iç dünyasına ve dışa yansıyan yönüne olan etkilerini psikanalistlerin görüşleri doğrultu-sunda değerlendirmeye çalıştık.

  2. Publications | Page 63 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 621 - 630 of 7205 ... For most countries, raising the minimum wage has long been considered a ... Zaman Talukder: Empowering women through food security ... development, which both have a strong impact on labour market inequality.

  3. Research Article Special Issue

    African Journals Online (AJOL)

    pc

    2018-05-16

    May 16, 2018 ... However, with a review of commercialized CAL applications [8], it is revealed ..... Zaman, B H. Digital storytelling design with augmented reality technology for ... mobile phones and services: survey, interview, and observation ...

  4. Overview of silkworm pathology in China | Guo-Ping | African ...

    African Journals Online (AJOL)

    In this study, we elaborated the history and progress of studies on silkworm diseases in China through summarizing and reviewing the achievements on silkworm pathology, pathogenic molecular biology, epidemiology, pathogen detection and diagnostic techniques, damage from non-infectious silkworm diseases and ...

  5. A note on analytical solutions of nonlinear fractional 2D heat ...

    Indian Academy of Sciences (India)

    Author Affiliations. O S IYIOLA1 F D ZAMAN2. Department of Mathematical Sciences, University of Wisconsin-Milwaukee, Wisconsin, USA; Department of Mathematics and Statistics, King Fahd University of Petroleum and Minerals, KFUPM, Dhahran, Saudi Arabia ...

  6. Interferensi Bahasa Daerah Terhadap Perkembangan Bahasa Indonesia

    OpenAIRE

    Irwan

    2006-01-01

    Bahasa Indonesia bersumber dari bahasa Melayu Riau yang mengalami perubahan dan perkembangan sitiap saat sesuai dengan perkembangan zaman. Bahasa Melayu Riau menjadi bahasa nasional dicetuskan pada tanggal 28 Oktober 1928 yang dikenal dengan Hari Sumpah Pemuda, oleh Irwan 06007435

  7. Systemic oxidatively generated DNA/RNA damage in clinical depression

    DEFF Research Database (Denmark)

    Jorgensen, Anders; Krogh, Jesper; Miskowiak, Kamilla

    2013-01-01

    oxidatively generated DNA and RNA damage, 8-oxo-7,8-dihydro-2-deoxyguanosine (8-oxodG) and 8-oxo-7,8-dihydroguanosine (8-oxoGuo), respectively, were determined in healthy controls (N=28), moderately depressed, non-medicated patients (N=26) and severely depressed patients eligible for electroconvulsive therapy...... for trend=0.004). The 8-oxoGuo excretion was further increased after clinically effective ECT compared with pre-ECT values (P=0.006). There were no differences in 8-oxodG excretion between the groups or pre- vs. post-ECT. LIMITATIONS: Small sample size and the inclusion of both unipolar and bipolar patients...

  8. Barış Harekâtı Sonrasında Adana’dan Kıbrıs’a Gerçekleştirilen Nüfus Nakli (1975-1976)

    OpenAIRE

    ÇANAK, Erdem

    2015-01-01

    1571-1878 yılları arasında Osmanlı Devleti’nin hâkimiyeti altında bulunan Kıbrıs, 1878 yılında geçici olarak, Lozan Antlaşması ile de resmen İngiltere’ye geçmiştir. Bu durumdan faydalanmak isteyen Rumlar da “Enosis”e yönelik faaliyetlerine hız vermişlerdir. Adadaki Türklerin var olma mücadelesine neden olan bu süreç, 1974 Barış Harekâtı ile neticelenmiştir. Ancak Türkler, Barış Harekâtı’na kadar olan dönemde maruz kaldıkları baskıdan dolayı zaman zaman başta Türkiye olmak üzere dünyanın farkl...

  9. EKONOMİK KRİZLER VE TÜRKİYE

    Directory of Open Access Journals (Sweden)

    Mehmet Fatih DARICAN

    2015-01-01

    Full Text Available Dünya ekonomisi yıllardır ekonomik istikrarsızlıklara karşı karşıya gelmiştir. Ekonomik istikrarsızlıklar beraberinde dünya devletlerini etkileyen ekonomik krizler meydana getirmiştir. Bu makalede dünyada yaşanan krizler ve bu krizlerin Türkiye'ye yansıması anlatılmıştır. Türkiye'deki krizlerin bir kısmı kendi içindeki problemlerden kaynaklanmış bir kısmı ise dünyadaki gelişmelerden dolayı ortaya çıkmıştır. Türkiye'deki ortaya çıkan krizler tek nedene bağlamak doğru olmaz. Kimi zaman siyasal nedenlerde kimi zaman arz talep dengesizliğinden bazen de bankaların tutumundan kaynaklanabilir. Bu örnekler ve kriz çeşitleri detaylı bir şekilde makalede yer almaktadır. Türkiye tarihinde bir çok defa darbe görmüş bu darbeler sonunda da kimi zaman krize sürüklenmiştir. Demokratik tutumun olup olmaması da ekonomik krizlerin ortaya çıkmasında etkili bir nedendir. Türkiye ilk ekonomik krizi 1929 Büyük bunalım adı ile anılan dünya çapındaki krizle yaşamış son olarak da 2008 deki küresel krizden etkilenmiştir.

  10. Naised leedu kunstnike pilgu läbi

    Index Scriptorium Estoniae

    2002-01-01

    Hansapanga galeriis leedu kaasaegse kunsti näitus "Õppides ja lauldes". Kuraator Kestutis Kuizinas. Osalevad Laura Stasiulyte, Gediminas ja Nomeda Urbonas, Vita Zaman. Videod ja slaidiprogrammid näitavad tõelisi või lavastatud episoode naiste elust tänapäeva Leedus

  11. From Denial to Participation: Turkey’s Evolving Discourse on Kurdish Nationalism

    Science.gov (United States)

    2013-09-01

    organization, but instead loosely affiliated nationalist gangs and organized crime syndicates that enjoyed immunity from prosecution thanks to their...Yilmaz, a prominent columnist of Gulen’s Zaman newspaper, wrote an article in 2013 entitled “I am Not a Nationalist,” in which he argued that while

  12. DEBUS BANTEN: Pergeseran Otentisitas dan Negosiasi Islam-Budaya Lokal

    Directory of Open Access Journals (Sweden)

    Kiki Muhamad Hakiki

    2017-03-01

    Full Text Available Sebagai suatu produk budaya, kesenian debus merepleksikan kompleksitas manusia itu sendiri. Di dalamnya terdapat kepentingan sosial, politik, bahkan nilai-nilai religi. Dalam historisitasnya debus mengalami pasang surut khususnya ketika berhadapan dengan perkembangan zaman dan nilai kelokalan. Artikel ini mengkaji apakah kesenian debus telah mengalami perubahan atau dengan kata lain terpengaruh oleh budaya lokal atau tidak. Hasil penelitian menemukan fakta bahwa kesenian debus nampaknya sudah mengalami pergeseran dan perubahan karena ia harus menyesuaikan diri agar tak ketinggalan zaman atau bahkan dilupakan. Kesenian debus saat ini sudah mengalami modifikasi yang ditunjukkan dengan banyak sekali hal-hal yang tak pernah dipraktekkan pada debus tempo dulu. Debus saat ini telah meninggalkan atau lepas dari asalnya yakni tarekat. Pergeseran itu terlihat dari segi ritual, gaya pertunjukan, pola perekrutan personil dan tujuan yang ingin dicapai. Kesenian debus sekarang lebih cenderung digunakan sebagai alat hiburan masyarakat atau menjadi komoditi pariwisata saja ketimbang sebagai suatu produk budaya yang mengandung nilai keagamaan.

  13. Küresel Ekonomik Kriz Türkiye İşgücü Piyasasında Cinsiyet Eşitsizliğini Derinleştirdi mi?

    OpenAIRE

    ÇETİNKAYA, Emel; YILDIRIMALP, Sinem

    2013-01-01

    İşgücü piyasalarında cinsiyet eşitsizliği, tüm dünyada olduğu gibi Türkiye işgücü piyasasında da önemli bir sorun olarak karşımıza çıkmaktadır. Zaman zaman yaşanan krizler işgücü piyasalarını ve özellikle kadın işgücünü olumsuz yönde etkilemektedir. 2007 yılında ABD’de başlayan küresel ekonomik kriz tüm ülke ekonomileri gibi Türkiye ekonomisini ve işgücü piyasalarını da 2008 yılının özellikle ikinci yarısından itibaren ciddi bir şekilde etkilemeye başlamıştır. Bu çalışma, küresel ekonomik kri...

  14. PSİKOLOJİK TACİZ OLGUSUNA 4857 SAYILI İŞ KANUNU AÇISINDAN BİR BAKIŞ

    OpenAIRE

    YILDIZ, Selver; KILKIŞ, İlknur

    2010-01-01

    Psikolojik taciz (mobbing), üstleri, çalışma arkadaşları ve astları tarafından çalışanın işten ayrılmasını sağlamak amacıyla hakkında söylenti çıkarılması, imalı sözlerde bulunulması, sindirilmeye çalışılması, itibarının zedelenmesi, dışlanması , alay edilmesi ve özellikle de onun küçük düşürülmesidir. Kurbanın yaşadığı bu süreç, zaman zaman intihara yol açabilecek kadar yıkıcı sonuçlara ulaşabilmektedir. Psikolojik taciz (mobbing) kavramı, Türkiye’de 2000’li yılların başından itibaren tartış...

  15. Dissolving and biodegradable microneedle technologies for transdermal sustained delivery of drug and vaccine

    Directory of Open Access Journals (Sweden)

    Hong X

    2013-09-01

    Full Text Available Xiaoyun Hong,1,2,* Liangming Wei,3,* Fei Wu,2,* Zaozhan Wu,2 Lizhu Chen,2 Zhenguo Liu,1 Weien Yuan2 1Department of Neurology, Xinhua Hospital, Shanghai, People's Republic of China; 2School of Pharmacy, Shanghai JiaoTong University, Shanghai, People's Republic of China; 3Research Institute of Micro/Nano Science and Technology, Shanghai JiaoTong University, Shanghai, People's Republic of China *These authors contributed equally to this work Abstract: Microneedles were first conceptualized for drug delivery many decades ago, overcoming the shortages and preserving the advantages of hypodermic needle and conventional transdermal drug-delivery systems to some extent. Dissolving and biodegradable microneedle technologies have been used for transdermal sustained deliveries of different drugs and vaccines. This review describes microneedle geometry and the representative dissolving and biodegradable microneedle delivery methods via the skin, followed by the fabricating methods. Finally, this review puts forward some perspectives that require further investigation. Keywords: microneedle, dissolving, biodegradable, sustained release

  16. The effects of water potential on some active forms of phosphorus in ...

    African Journals Online (AJOL)

    MICHAEL

    transformations by measuring soil respiration rates, microbial biomass carbon, N mineralization and nitrification (Thomsen et al., 1999; Salamanca et al.,. 2003; Zaman and Chang, 2004). Bioavailable P from organic manures is mainly in the dissolved form. It occupies only a small fraction of total P and particulate organic P ...

  17. Research Article Special Issue

    African Journals Online (AJOL)

    pc

    2018-05-16

    May 16, 2018 ... learning materials for low-achieving children. ... [3], [5]. In contrast, the lacking of an appropriate design concept leads to inefficiency of ... early primary years, these children are also screened using standard ..... [10] Abas H & Zaman, B H. Digital storytelling design with augmented reality technology for.

  18. PARP-1 expression is increased in colon adenoma and carcinoma and correlates with OGG1.

    Directory of Open Access Journals (Sweden)

    Tomasz Dziaman

    Full Text Available The ethiology of colon cancer is largely dependent on inflammation driven oxidative stress. The analysis of 8-oxodeoxyguanosine (8-oxodGuo level in leukocyte DNA of healthy controls (138 individuals, patients with benign adenomas (AD, 137 individuals and with malignant carcinomas (CRC, 169 individuals revealed a significant increase in the level of 8-oxodGuo in leukocyte DNA of AD and CRC patients in comparison to controls. The counteracting mechanism is base excision repair, in which OGG1 and PARP-1 play a key role. We investigated the level of PARP-1 and OGG1 mRNA and protein in diseased and marginal, normal tissues taken from AD and CRC patients and in leukocytes taken from the patients as well as from healthy subjects. In colon tumors the PARP-1 mRNA level was higher than in unaffected colon tissue and in polyp tissues. A high positive correlation was found between PARP-1 and OGG1 mRNA levels in all investigated tissues. This suggests reciprocal influence of PARP-1 and OGG1 on their expression and stability, and may contribute to progression of colon cancer. PARP-1 and OGG1 proteins level was several fold higher in polyps and CRC in comparison to normal colon tissues. Individuals bearing the Cys326Cys genotype of OGG1 were characterized by higher PARP-1 protein level in diseased tissues than the Ser326Cys and Ser326Ser genotypes. Aforementioned result may suggest that the diseased cells with polymorphic OGG1 recruit more PARP protein, which is necessary to remove 8-oxodGuo. Thus, patients with decreased activity of OGG1/polymorphism of the OGG1 gene and higher 8-oxodGuo level may be more susceptible to treatment with PARP-1 inhibitors.

  19. Well-posedness and decay for the dissipative system modeling electro-hydrodynamics in negative Besov spaces

    Science.gov (United States)

    Zhao, Jihong; Liu, Qiao

    2017-07-01

    In Guo and Wang (2012) [10], Y. Guo and Y. Wang developed a general new energy method for proving the optimal time decay rates of the solutions to dissipative equations. In this paper, we generalize this method in the framework of homogeneous Besov spaces. Moreover, we apply this method to a model arising from electro-hydrodynamics, which is a strongly coupled system of the Navier-Stokes equations and the Poisson-Nernst-Planck equations through charge transport and external forcing terms. We show that some weighted negative Besov norms of solutions are preserved along time evolution, and obtain the optimal time decay rates of the higher-order spatial derivatives of solutions by the Fourier splitting approach and the interpolation techniques.

  20. A Solution Method for Large Deformation Contact Problems.

    Science.gov (United States)

    1984-10-01

    15] Desai, C.S., Zaman, M.M., Lightner , J.G., and Siriwardane, H.J., "Thin Element for Interfaces and Joints," Int. J. Anal. and Num. Meth. in...Urbana, IL 61801 SMCCR-SPS-IL 1 Massachusetts Institute of Technology Aeroelastic and Structures Research Laboratory ATTN: Dr. E. A. Witmer Cambridge

  1. “Membaca Zaman": Refleksi Pemikiran Jeihan dalam Lukisannya, 1953-2012

    Directory of Open Access Journals (Sweden)

    Herliyana Rosalinda

    2017-06-01

    Full Text Available This research examines on the reflection ofJeihan's thoughttraced via his paintingsproduced during 1953 until 2012. It uses historical method with hermeneutical approach. Jeihan’s childhood experienced abnormalities, that made him marginalized in his family and social environment. As the result, his personality became rough and rebellious. It affected his painting style that tend to be harsh and had no character. This bad temper attached him until 1953, when Jeihan studied painting in Himpunan Budaya Surakarta (HBS, and continued his higher education to Institut Teknologi Bandung (ITB. In order to understand painting style, it can be seen from line and color paintings that always progressed. It can be analyzed into four periods which colored by a different artistic style, that are seeking (1952-1965, discovery (1965-1975, maturation (1975-1985, and reaping period (1986-2012.

  2. Zaman Talukder : L'autonomisation des femmes au moyen de la ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    27 mars 2015 ... ... household food security and nutrition in Cambodia » (renforcer la production alimentaire de subsistance afin d'améliorer la sécurité alimentaire des ménages et la nutrition au Cambodge). Le projet est financé par le CRDI et le gouvernement du Canada par l'entremise d'affaires étrangères, Commerce et ...

  3. Asjade tegemisest / Mari Laaniste

    Index Scriptorium Estoniae

    Laaniste, Mari, 1977-

    1999-01-01

    Issey Miyake (s. 1938) näitus "Making Things" Cartier' moodsa kunsti keskuses Raspail' bulvaril Pariisis. Külaliskunstnikud Yasumasa Morimura, Nobuyoshi Araki (fotograaf), Tim Hawkinson, Cai Guo-Qiang.

  4. Phase stability of superconductive Y1Ba2Cu4O8

    International Nuclear Information System (INIS)

    Hegde, M.S.; Kumaraswamy, B.V.; Pandey, S.P.; Narlikar, A.V.

    1997-01-01

    The stability of the 124 superconductive phase YBa 2 Cu 4 O 8 upon exposure to air and saturated humidity at ambient temperature has been studied by thermogravimetry, X-ray diffraction, and ac susceptometry. Extent of phase conversion was monitored by TG and confirmed by XRD and ac susceptometry. 124 samples upon prolonged exposure to air were found to be no longer phase-pure, with partial conversion to 123 and CuO. On oxygen annealing, reconversion of 123 + GuO to 124 was observed. However, upon prolonged exposure to saturated humid conditions, phase-pure 124 dissociated irreversibly into 211, GuO, and a highly disordered 124-like structure with planar defects along many hkl indices and was found to be nonsuperconducting even up to 60 K

  5. Fixed-point theorems for families of weakly non-expansive maps

    Science.gov (United States)

    Mai, Jie-Hua; Liu, Xin-He

    2007-10-01

    In this paper, we present some fixed-point theorems for families of weakly non-expansive maps under some relatively weaker and more general conditions. Our results generalize and improve several results due to Jungck [G. Jungck, Fixed points via a generalized local commutativity, Int. J. Math. Math. Sci. 25 (8) (2001) 497-507], Jachymski [J. Jachymski, A generalization of the theorem by Rhoades and Watson for contractive type mappings, Math. Japon. 38 (6) (1993) 1095-1102], Guo [C. Guo, An extension of fixed point theorem of Krasnoselski, Chinese J. Math. (P.O.C.) 21 (1) (1993) 13-20], Rhoades [B.E. Rhoades, A comparison of various definitions of contractive mappings, Trans. Amer. Math. Soc. 226 (1977) 257-290], and others.

  6. Peran Mukti Ali dalam Pengembangan Toleransi Antar Agama di Indonesia

    Directory of Open Access Journals (Sweden)

    Khairah Husin

    2014-06-01

    Full Text Available Agama sebagai sasaran kajian penelitian sudah banyak dilakukan oleh para sarjana disiplin ilmu. Mereka melakukan penelitian terhadap berbagai aspek dari agama, baik aspek ide maupun aspek perwujudan dalam kenyataan. Dimulai dari keyakinan dan ajaran yang dimiliki oleh suatu agama hingga pengaruh agama pada kehidupan masyarakat pemeluk agama tersebut. Kalau yang dimaksud metode dalam ilmu perbandingan agama adalah cara untuk memperoleh dan mamahami kebenaran agama dari realitas empiris, atau lebih tepatnya “kebenaran ilmiah agamis”, maka pendekatan tiada lain adalah suatu sikap ilmiah (persepsi dari seorang yang harus ditunjukkan untuk menemukan kebenaran ilmiah yang hendak diperoleh. Dengan demikian pendekatan sifatnya umum. Dalan suatu pendekatan tertentu dapat digunakan bermacammacam metode, umpamanya seorang Sosiolog akan mengkaji agama pasti akan menerapkan pendekatan metode-metode sosiologis. Begitu pula Sejarawan, Antropolog, Fenomenolog, dan lain-lain akan menerapkan pendekatan dan metode sesuai dengan latar belakang keahliannya. Maka sasaran ideal dari beberapa pendekatan adalah memperoleh interelasi yang sistematis dari fakta-fakta agama, dan bertujuan untuk mencari jawaban tentang fakta-fakta tersebut dengan menggunakan kesangsian sistematis. Pendekatan keilmuan dalam meneliti agama mencoba mendeskripsikan dunia pemeluk agama secara apa adanya (das sein, bukan didasarkan semestinya secara normatif (das sollen. Dengan demikian, pendekatan keilmuan yang empiris ini menggunakan dan mengadaptasi pendekatanpendekatan ilmu-ilmu sosial dan budaya. Dari sekian tokoh ilmu Perbandingan Agama, kebanyakan dari mereka merupakan ilmuwan Barat. Namun demikian ada juga beberapa tokoh perbandingan agama dari duni Islam, antara lain adalah Prof. Dr. H.A. Mukti Ali, Ibnu Hazm dan As-Syahrastani. Sementara Ibnu Hazm Al Andalusy dan As-Syahrastani merupakan tokoh-tokoh Perbaga Muslim dari zaman klasik – zaman ketika Perbaga belum terbentuk sebagai

  7. Productivity Problems and Remedies for Cereals Farming in Sivas

    Directory of Open Access Journals (Sweden)

    Sancar Bulut

    2016-07-01

    Full Text Available Yörede, tarımsal işletmelerde sermaye ve teknik bilginin yetersiz oluşu, tarımla uğraşan nüfusun yaşlı ve eğitim düzeyinin düşüklüğü, yeterince teknik eleman olmayışına bağlı olarak tarımsal kuruluşların tarımsal yayım faaliyetleri konusunda yetersiz kalması ve zaman zaman iklim koşullarında yaşanan olumsuzluklar tahıl üretimi ve verimliliğini ekonomik olarak olumsuz etkilemektedir. Ayrıca, ilde monokültür tahıl tarım alanlarında yüksek oranda nadas uygulanması, sertifikalı tohumluk kullanımının yetersiz olması, toprak işleme ve tohum yatağı hazırlığındaki yanlışlıklar, kışlık ekimlerin geciktirilmesi ya da yüksek oranda yazlık ekim yapılması (özellikle arpada, yüksek maliyet nedeniyle kimyasal gübre kullanımındaki yetersizlikler, tahıllar konusunda bilimsel araştırma eksikliği ve yabancı ot mücadelesinin zamanında yapılmaması tahıl verimlerini pratikte uygulanan yada uygulanamayan sebeplerden dolayı önemli ölçüde sınırlamaktadır. Sivas’ta tahıl tarımında yüksek verim elde etmek için gerek ekonomik ve gerekse teorik bu eksiklikler mutlaka giderilmelidir.

  8. The influence of Self-Concept into the Self Esteem in the Orphanage

    Directory of Open Access Journals (Sweden)

    Erna Multahada

    2016-06-01

    Full Text Available Abstract The influence of self-concept into the selfesteem in the orphanage adolescent Akhiruz Zaman is the aim of this research. The participant is from 80 adolescents (in age 13-21 who stay in orphanage X. the subject is taken randomly using two questionnaire, they are: self-concept questionnaire and selfesteem questionnaire. The result is there is the influence of self-concept into the self-esteem of adolescent. The contribution of it is 18.5% with significant P = 0,000 which is very significant. It has the rest in 81, 5% caused by other factors. It concludes that the matter of adolescent selfesteem that stays in orphanage, one of the factors is caused by the concepts of themselves.. Abstrak Pengaruh konsep diri kterhadap kepercayaan diri di panti asuhan remaja Akhiruz Zaman adalah tujuan dari penelitian ini. Peserta meliputi 80 remaja (usia 13-21 tahun yang tinggal di panti asuhan X. Subjek penelitian dipilih secara acak menggunakan dua kuisioner, yaitu kuisioner konsep diri dan kuisioner kepercayaan diri. Hasil menunjukkan bahwa terdapat pengaruh konsep diri dengan kepercayaan diri pada remaja. Kontribusi sebesar 18,5% dengan signifikansi p = 0,000 yakni sangat signifikan 81,5% sisanya, disebabkan oleh faktor-faktor lain. Dapat disimpulkan bahwa masalah kepercayaan diri remaja yang tinggal di panti asuhan, salah satunya disebabkan oleh konsep diri mereka. How to Cite : Multahada, E. Mabelle, M. (2015. The Influence of Self-Concept into the Self Esteem in the Orphanage Adolescent  Akhiruz Zaman Bekasi, West Java. TARBIYA: Journal Of Education In Muslim Society, 2(2, 117-122. doi:10.15408/tjems.v2i2.2804. Permalink/DOI: http://dx.doi.org/10.15408/tjems.v2i2.2804

  9. Adult Literacy and the Poor Farming People.

    Science.gov (United States)

    Mathur, J. C.

    1978-01-01

    In discussing Rafe-uz-Zaman's essay on adult literacy and national development (see v9, n1 of this journal), the author cites examples to support his thesis that mass literacy campaigns in predominately agricultural countries can be successful only if there is simultaneous undertaking of economic development programs focused on the rural poor. (MF)

  10. Râzî’nin, Kur’an’daki Yeryüzü (Arz Âyetleriyle İlgili Tefsir-i Kebir’deki Yorumları: Modern Jeoloji Biliminin Verileriyle Kısa Bir Mukayese

    Directory of Open Access Journals (Sweden)

    Enver BAYRAM

    2012-03-01

    Full Text Available Batı dünyasında bilimsel buluş ve keşiflerin yeni başladığı bir dönemde, İslam dünyasında birçok bilimsel buluş ve keşif Müslüman bilim adamları tarafından ortaya konulmuştur. Bu buluş ve keşiflerin yapıldığı alanlardan biri de Jeoloji (yer ilmidir. Bu konuyu tefsirinde etraflıca ele alan Râzî (ö. 606/1210, yer ile ilgili âyetleri kendi döneminin ilmi verileri doğrultusunda ayrıntılı bir şekilde tefsir etmiştir. Bu yüzden onun bazı açıklamaları, zaman zaman modern Jeoloji ilminin verilerine ters düşebilmektedir. Onun, bu âyetleri tefsir ederken en temel amacı, bunları Allah’ın varlığına ve birliğine delil getirmesi olmuştur.

  11. Pengembangan Game Edukatif G30S/PKI Berbasis Android

    Directory of Open Access Journals (Sweden)

    Annisa Hedlina Hendraputri

    2014-11-01

    Full Text Available Gaya hidup masyarakat zaman sekarang tak pernah lepas dari kemajuan teknologi. Masyarakat menengah keatas, baik dari anak-anak hingga orang dewasa, hampir tidak ada yang tidak meggunakan perangkat mobile seperti handphone atau tablet. Namun sayangnya masyarakat zaman sekarang cenderung apatis dengan kondisi sekitarnya, bahkan tidak mengenal sejarah negaranya. Penelitian ini dilakukan untuk mendekatkan kembali anak-anak dengan sejarah terutama peristiwa G30S/PKI melalui game perangkat seluler berbasis Android. Penelitian ini dilakukan dengan menerapkan tahap pengembangan MDLC (Multimedia Development Life Cycle mulai dari tahap penentuan konsep sampai dengan sidtribusi. Sebagai sumber yang relevan, cerita sejarah diambil langsung dari Monumen Pancasila Sakti di Lubang Buaya, Jakarta Timur, sebagai salah satu tempat bersejarah yang erat kaitannya dengan peristiwa G30S/PKI. Hasil dari penelitian ini berupa suatu aplikasi permainan yang menceritakan peristiwa sejarah G30S/PKI yang dikemas menjadi aplikasi perangkat seluler dengan sistem operasi Android. Penelitian ini diharapkan mampu menarik minat anak-anak khususnya usia 9 sampai dengan 12 tahun untuk mempelajari dan mencintai sejarah Indonesia.

  12. Uncovering Our History, Teaching Primary Sources (Tarihimizi Keşfetme, Birincil Kaynaklarla Öğretim - Susan H. Veccia

    Directory of Open Access Journals (Sweden)

    Duygu Alphan Şentuna

    2014-05-01

    Full Text Available Okul yıllarından bahseden insanların büyük bir çoğunluğu için tarih dersi, not almak için isimlerin ve tarihlerin ezberlendiği, sınavdan sonra ise unutulduğu bir ders olarak hatıralarda yer alır. Günümüzde tarih öğretiminde önemli gelişmeler olmasına rağmen hala derslerde öğretmenlerin isim, tarih ve ders kitabı merkezli bir öğretim izledikleri görülmektedir. Öğrencilerin eleştirel ve tarihsel düşünme becerisi elde etmeleri için ilk önce bilgiye sahip olmaları gerektiği inancı, öğretmenlerin derslerde yenilikçi yöntemlere yeterli zaman ayırmalarını engellemektedir. Bu durum öğrencilerin tarih dersinden soğumalarına ve dersi zaman kaybı olarak görmelerine neden olmaktadır.

  13. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    De Tian1 Lin Guo1. Orthopedics Department, Hospital of Dalian University, Dalian 116 001, China; School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang, China; The Nursing Department, Affiliated Zhongshan ...

  14. Larger yield of cyclobutane dimers than 8-oxo-7,8-dihydroguanine in the DNA of UVA-irradiated human skin cells

    International Nuclear Information System (INIS)

    Courdavault, Sophie; Baudouin, Caroline; Charveron, Marie; Favier, Alain; Cadet, Jean; Douki, Thierry

    2004-01-01

    Exposure to solar ultraviolet light is the major cause of most skin cancers. While the genotoxic properties of UVB radiation are now well understood, the DNA damaging processes triggered by less energetic but more abundant UVA photons remain to be elucidated. Evidence has been provided for the induction of oxidative lesions to cellular DNA including strand breaks and 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo). Formation of cyclobutane pyrimidine dimers (CPDs) has also been reported, mostly in rodent cells. In order to gain insights into the relevance of the latter photoproducts in UVA-mutagenesis of human skin, we quantified the level of 8-oxodGuo and CPDs within primary cultures of normal fibroblasts and keratinocytes using specific chromatographic assays. The yield of formation of CPDs was found to be higher than that of 8-oxodGuo in both cell types. In addition, CPDs were mostly TT derivatives, and neither (6-4) photoproducts nor Dewar valence isomers were detected. These observations are reminiscent of results obtained in rodent cells and suggest that a photosensitized triplet energy transfer occurs and that this reaction is more efficient than photooxidation of DNA components. The predominant formation of CPDs with respect to oxidative damage within normal human skin cells exposed to UVA radiation should be taken into account in photoprotection strategies

  15. Larger yield of cyclobutane dimers than 8-oxo-7,8-dihydroguanine in the DNA of UVA-irradiated human skin cells

    Energy Technology Data Exchange (ETDEWEB)

    Courdavault, Sophie [Laboratoire Lesions des Acides Nucleiques, Service de Chimie Inorganique et Biologique, CEA/DSM/Departement de Recherche Fondamentale sur la Matiere Condensee, CEA-Grenoble, 17, avenue des Martyrs, 38054 Grenoble Cedex 9 (France); Baudouin, Caroline [Institut de Recherche Pierre Fabre, Laboratoire de Biologie Cellulaire, Toulouse (France); Charveron, Marie [Institut de Recherche Pierre Fabre, Laboratoire de Biologie Cellulaire, Toulouse (France); Favier, Alain [Laboratoire Lesions des Acides Nucleiques, Service de Chimie Inorganique et Biologique, CEA/DSM/Departement de Recherche Fondamentale sur la Matiere Condensee, CEA-Grenoble, 17, avenue des Martyrs, 38054 Grenoble Cedex 9 (France); Cadet, Jean [Laboratoire Lesions des Acides Nucleiques, Service de Chimie Inorganique et Biologique, CEA/DSM/Departement de Recherche Fondamentale sur la Matiere Condensee, CEA-Grenoble, 17, avenue des Martyrs, 38054 Grenoble Cedex 9 (France); Douki, Thierry [Laboratoire Lesions des Acides Nucleiques, Service de Chimie Inorganique et Biologique, CEA/DSM/Departement de Recherche Fondamentale sur la Matiere Condensee, CEA-Grenoble, 17, avenue des Martyrs, 38054 Grenoble Cedex 9 (France)]. E-mail: tdouki@cea.fr

    2004-11-22

    Exposure to solar ultraviolet light is the major cause of most skin cancers. While the genotoxic properties of UVB radiation are now well understood, the DNA damaging processes triggered by less energetic but more abundant UVA photons remain to be elucidated. Evidence has been provided for the induction of oxidative lesions to cellular DNA including strand breaks and 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo). Formation of cyclobutane pyrimidine dimers (CPDs) has also been reported, mostly in rodent cells. In order to gain insights into the relevance of the latter photoproducts in UVA-mutagenesis of human skin, we quantified the level of 8-oxodGuo and CPDs within primary cultures of normal fibroblasts and keratinocytes using specific chromatographic assays. The yield of formation of CPDs was found to be higher than that of 8-oxodGuo in both cell types. In addition, CPDs were mostly TT derivatives, and neither (6-4) photoproducts nor Dewar valence isomers were detected. These observations are reminiscent of results obtained in rodent cells and suggest that a photosensitized triplet energy transfer occurs and that this reaction is more efficient than photooxidation of DNA components. The predominant formation of CPDs with respect to oxidative damage within normal human skin cells exposed to UVA radiation should be taken into account in photoprotection strategies.0.

  16. In vitro clonal propagation of the neem tree ( Azadirachta indica A ...

    African Journals Online (AJOL)

    In vitro clonal propagation of the neem tree (Azadirachta indica A. Juss.) M Shahin-uz-zaman, M Ashrafuzzaman, MS Haque, LN Luna. Abstract. A study was conducted with root and shoot tip explants of neem to develop an efficient protocol of regeneration. Shoot tips and root tips from 10 - 20 days old seedlings of neem ...

  17. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 80; Issue 5. Issue front cover thumbnail. Volume 80, Issue 5. May 2013, pages 739-915. pp 739-755. The symmetries and conservation laws of some Gordon-type equations in Milne space-time · S Jamal A H Kara A H Bokhari F D Zaman · More Details Abstract Fulltext ...

  18. Dramaturgi Kepemimpinan Perempuan dalam Organisasi Profit

    OpenAIRE

    Negari, Leidena Sekar; Sunarto, Sunarto; Lukmantoro, Triyono

    2013-01-01

    DRAMATURGI KEPEMIMPINAN PEREMPUAN DALAMORGANISASI PROFITAbstrakPemimpin dalam organisasi biasanya didominasi oleh kaum pria, karena konsepdan tradisi yang dimiliki oleh masyarakat Indonesia yang mengaut pahampaternalistik. Seiring perkembangan zaman perempuan kini mampu mendudukijajaran top tier manajemen di sejumlah organisasi profit. Gaya komunikasiperempuan yang dianggap mampu dicintai karyawan dan lingkungan kerjanyadalam membangun sebuah hubungan menjadi sebuah nilai plus.Di dalam peneli...

  19. Optimization of ultrasonic extraction of mycelial polysaccharides ...

    African Journals Online (AJOL)

    ajl yemi

    2011-11-28

    Nov 28, 2011 ... Research Center for Entomogenous Fungi; BBD, Box-Behnken design; DPPH, 2 ... Dr. Y.L. Guo (Institute of Microbiology, Chinese Academy of. Sciences), is ... experimental design, data analysis, quadratic model building and.

  20. Ten polymorphic microsatellite markers characterized for ...

    Indian Academy of Sciences (India)

    MING MING BAO

    development of new microsatellite primers is expensive and time-consuming, whereas ... constructing microsatellite-enriched libraries (Guo et al. 2013). Thirteen markers .... Due to the influence of human activities, stocks of this species have ...

  1. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Juan Li1 Ruisong Guo1 Hong Jiang2. Key Laboratory of Advanced Ceramics and Machining Technology, Ministry of Education, Tianjin University, Tianjin 300072, China; Guizhou Broadcasting and Television College, Guiyang 550004, China ...

  2. Effects of temperature, light, desiccation and cold storage on ...

    African Journals Online (AJOL)

    oyaide

    2015-03-25

    Mar 25, 2015 ... conservation (Hong and Ellis, 1996; Linington and. Pritchard, 2001). .... Taking into account final mean germination percentages ... Guo from the Center for Conservation of Medicinal. Plants ... Ma QY, Wei Z (1994). Flora of ...

  3. Symmetry and conservation law structures of some anti-self-dual ...

    Indian Academy of Sciences (India)

    2016-09-28

    Sep 28, 2016 ... (2016) 87: 64 c Indian Academy of Sciences. DOI 10.1007/s12043-016-1258-y. Symmetry and conservation law structures of some anti-self-dual (ASD) manifolds. J BASINGWA1, A H KARA1,∗, ASHFAQUE H BOKHARI2, R A MOUSA2 and F D ZAMAN2. 1School of Mathematics, University of the ...

  4. Bauran Pemasaran Jasa, Pengaruhnya terhadap Kepuasan Konsumen Pengguna Mobil Toyota Avanza Veloz PT. Hasjrat Abadi Manado

    OpenAIRE

    Wowor, Valdy Ronald

    2013-01-01

    Perkembangan teknologi dunia yang sangat pesat saat ini, menyebabkan semua Perusahaan perotomotifan harus berpikir lebih keras untuk menciptakan produk yang unggul dengan menerapkan strategi-strategi pemasaran. Bauran Pemasaran merupakan salah satu strategi pemasaran untuk meningkatkan jumlah penjualan sebuah produk. Seiring dengan perkembangan zaman, kini orientasi berpikir Perusahaan perotomotifan tidak saja pada penciptaan produk unggul, namun bagaimana kepuasan konsumen menjadi tujuan uta...

  5. Mengubah Jarak dengan Penerapan Remote Access Menggunakan Team Viewer

    OpenAIRE

    Fahlepi Roma Doni; Ibnu Dwi Lesmono

    2018-01-01

    Seiringsemakin maju berkembangan zaman maka teknologi ikut berkembang juga, khususnya teknologi aplikasi yang menunjukkan kemajuan, infrastruktur di bidang komunikasi yang bisa mendukung untuk terciptanya sistem atau aplikasi yang handal ikut mengalami perkembangan pesat juga. Teknologi yang digunakan supaya bisa mengendalikan komputer dari yang berbeda tempat atau wilayah dengan menggunakan sebuah aplikasi remote access, menggunakan aplikasi ini seolah-olah akan berada didepan komputer yang ...

  6. E-Goverment Sembakodroid Monitoring Harga Sembako Berbasis Android

    OpenAIRE

    Ahmad Fahriyannur Rosyady; Risnandar Risnandar; Izzatul Ummah

    2013-01-01

    ABSTRAK Seiring dengan perkembangan zaman dan teknologi yang begitu pesat, banyak manusia yang tidak dapat dipisahkan dari teknologi. Hal ini menyebabkan banyaknya instansi pemerintah yang memanfaatkan teknologi khususnya di bidang Information Technology (IT) dalam menjalankan business process dalam pemerintahan. Dinas Perindustrian dan Perdagangan (Disperindag) Provinsi Jawa Barat merupakan sebuah Dinas yang bertugas untuk mengatur dan mengawasi  jalannya arus perdagangan di Jawa Barat. ...

  7. 86 Optimisation du dimensionnement des systèmes photovoltaïques ...

    African Journals Online (AJOL)

    REMI

    This paper is treated a comparison of the energy received by solar panels using two ..... [20] - TAO YU and GUO WENCHENG, Study on tracking strategy of automatic ... on CPV Generation, 2010 International Conference on Intelligent System ...

  8. Molecular cloning and characterization of a novel human kinase ...

    Indian Academy of Sciences (India)

    Unknown

    LINGCHEN GUO, CHAONENG JI, SHAOHUA GU, KANG YING, HAIPENG CHENG,. XIAOGHUA NI ... minal LIM domain proteins that cantain a PDZ domain at the amino terminal ..... Taira M., Evrard J. L., Steinmetz A. and Dawid I. B. 1995.

  9. Lingkungan dan Pemukiman Zaman Kerajaan Majapahit dalam Cgi (Computer Generated Imagery

    Directory of Open Access Journals (Sweden)

    Ardiyansah Ardiyansah

    2010-10-01

    Full Text Available Majapahit is believed to be a great civilization that once have been victorious in our archipelago. Although much is known about the Majapahit, but it turns out more obscure facts have not been revealed and need to be explored in more depth. One is how the people of Majapahit live their life, how they built the civilization by building houses and how they manage their social environment. Using CGI (Computer Generated Imagery Technology a "replica" Majapahit life can be built by combining the findings of archaeological and engineering-based digital animation 3d. 

  10. Tam Zamanında Üretim Sistemlerinde Hata Önleyiciler: Poka-

    OpenAIRE

    BAY, Murat; ÇİÇEK, Ercan

    2007-01-01

    Günümüzde, birçok işletme yalın üretime üretim performansının artması için geçmektedir. İstatistiksel proses kontrol gibi araçlar hatayı göstermekte, ancak önlememektedir. Poka-Yoke’nin altında yatan temel düşünce ise, çalışanların dikkatsizliklerini önlemektir. Bu çalışmada, poka-yoke sistemleri özellikle kurulum ve kullanım maliyetinin düşük olması ve maliyet kazancı olduğu için incelenmiştir

  11. BUDAYA MEDIA DAN LAHIRNYA SPECTACLE SOCIETY (Televisi sebagai Voyeurism Zaman Modern

    Directory of Open Access Journals (Sweden)

    Reza Aprianti

    2015-12-01

    Full Text Available Starting from the habit of "peek" and want to know the problems that other people have indirectly fueled the spectacle culture and society becomes increasingly masiv with the help of mass media. This applies also in Indonesian society seen from the number of television programs on average gives a presentation that are peeking problems of others. Although this culture has become mass culture, based on research results are acceptable in some countries the effects of this culture more negatively charged than the positive.

  12. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. PING-YING TANG1 GUO-HUA HUANG1 QING-LIAN XIE1 JIAN-YING LI1. Key Laboratory of New Electric Functional Materials of Guangxi Colleges and Universities, Guangxi Teachers Education University, Nanning 530023, China ...

  13. Cloning and expression trait of UDP-glucose:flavonoid 3-O ...

    African Journals Online (AJOL)

    user1

    2012-09-04

    Sep 4, 2012 ... the pigmentation of flower, fruit and seed (Tanaka et al.,. 2008). ... (UV) can regulate anthocyanin biosynthesis in plants. (Guo et al. ..... from the seed coat of black soybean (Glycine max (L.) Merr.). ... Structure and expression.

  14. Porcine circovirus type 2 ORF4 protein binds heavy chain ferritin

    Indian Academy of Sciences (India)

    Porcine circovirus type 2 ORF4 protein binds heavy chain ferritin. Qizhuang Lv Kangkang Guo Tao Wang ... Keywords. Cellular protein; FHC; ORF4 protein; porcine circovirus type 2 (PCV2); yeast two-hybrid ... Journal of Biosciences | News ...

  15. Evaluation of Anti-tumor and Chemoresistance-lowering Effects of ...

    African Journals Online (AJOL)

    Evaluation of Anti-tumor and Chemoresistance-lowering Effects of Pectolinarigenin from Cirsium japonicum Fisch ex DC in Breast Cancer. Mingqian Lu, Xinhua Xu, Hongda Lu, Zhongxin Lu, Bingqing Xu, Chao Tan, Kezhi Shi, Rong Guo, Qingzhi Kong ...

  16. Tüketici Fiyat Endeksinin Uyarlamalı Ağa Dayalı Bulanık Çıkarım Sistemi ile Kestirimi / Consumer Price Index Forecast with Adaptive Neuro Fuzzy Inference System

    Directory of Open Access Journals (Sweden)

    Serenay VAROL

    2016-04-01

    Full Text Available Son yıllarda zaman serisi tahmini için birçok alternatif yöntem önerilmiştir. Uyarlamalı ağa dayalı bulanık çıkarım sistemi (ANFIS öngörü problemi için literatürde en çok uygulanan bulanık çıkarım sistemidir. Bu çalışmada tüketici fiyat endeksinin kestiriminde ANFIS’in performansı incelenmiştir. Çalışmanın sonucunda ANFIS yöntemi ile ilgilenilen zaman aralığındaki tüketici fiyat endeksinin kestiriminde ulaşılan sonuçlar yorumlanmıştır. / Alternative methods have been proposed for time series prediction in last years. Adaptive neuro fuzzy inference system (ANFIS is the most used fuzzy inference system in literature for prediction problem. In this study, the performance of ANFIS in forecasting consumer price index is examined, and the results of the consumer price index estimation in time period, on which ANFIS method is applied, are interpreted.

  17. Human epidermal growth factor receptor (HER 2)/neu expression ...

    African Journals Online (AJOL)

    use

    2011-11-23

    Nov 23, 2011 ... expression and gene amplification in colorectal cancer. Wei Deng 1, Wei-Guo .... patients whose clinical data (include diagnosis, age, sex, address, disease history, etc) intact ..... Anal Cell Pathol.10: 149-160. Tapia C, Glatz K, ...

  18. African Journal of Biotechnology - Vol 11, No 41 (2012)

    African Journals Online (AJOL)

    Lenaldo Muniz de Oliveira, Nayra da Silva Negreiros Cardoso, Luzimar Gonzaga .... Ju-Hong Zhang, Jian-Ying Guo, Jing-Yuan Xia, Fang-Hao Wan, 9873-9880 ... Zhu Xiao-yan, Chang Shu-juan, Zhang Ying-jun, Luo Hai-ling, 9894-9905.

  19. Use of co-spray pyrolysis for synthesizing nitrogen-doped TiO2 films

    Indian Academy of Sciences (India)

    the photoelectrochemical solar cell (Guo et al 2011; Zhang et al 2011; Umar et al ... as photocatalytic mechanism, bandgap narrowing, N 1s XPS assignment were ..... This work was supported by the Vietnam National Founda- tion for Science ...

  20. Disease: H00801 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Z, Cai B, Hostetler EM, Moran R, Liang D, Estrera A, Safi HJ, Leal SM, Bamshad MJ, Shendure J, Nickerson DA,... ... AUTHORS ... Guo DC, Regalado ES, Gong L, Duan X, Santos-Cortez RL, Arnaud P, Ren

  1. Reforming the American Military Officer Personnel System

    Science.gov (United States)

    2015-12-02

    Lamping Lewis, Henry Leonard, Julia Pollak, Christopher Guo and Bernard Rostker, Tour Lengths, Permanent Changes of Station, and Alternatives for...Raymond E. Conley, Stephanie Young, William A. Williams, Jeffrey Engstrom, Barbara Bicksler, Sara Beth Elson, Joseph Jenkins , Lianne Kennedy

  2. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Hong Zhang Teng-Long Guo Qing-Lian Wang · More Details Abstract Fulltext PDF. Three transgenic cotton varieties (lines) were chosen for the study of inheritance and segregation of foreign Bt (Bacillus thuringiensis toxin) and tfdA genes in cotton.

  3. A systematic analysis of the association studies between CASP8 ...

    Indian Academy of Sciences (India)

    Yinliang Zhang

    Yinliang Zhang and Wei Li contributed equally to this work. ... All original articles published in English that examined the ... goodness of fit is used to test deviation from HWE. Studies were considered to deviate from HWE at P < 0.05 (Guo.

  4. Hiinlased tahavad ehitada Ringtee silda

    Index Scriptorium Estoniae

    2007-01-01

    2007. a. suvel kohtusid Tartu linnajuhtidega Shangai projekteerimisfirma Lin Tung-Yen & Li Guo-Hao Consultants Ltd ja Jiangsu provintsist pärit ehitusfirma Jiangyn Bridge Engineering Ltd esindajad, et esitada oma nägemus Tartusse planeeritavast Ringtee sillast. Anto Ili kommentaar

  5. Road Materials and Pavement Design, Volume 17(3)

    CSIR Research Space (South Africa)

    De Beer, Morris

    2016-03-01

    Full Text Available Environment, Pretoria, South Africa Jo Sias Daniel - University of New Hampshire, USA Zhongyin Guo - Tongji University, Shanghai, P.R. of China Kwang W. Kim - Kangwon National University, Republic of Korea Niki Kringos - KTH Royal Institute of Technology...

  6. Road Materials and Pavement Design volume 17(4).

    CSIR Research Space (South Africa)

    De Beer, Morris

    2016-03-01

    Full Text Available Environment, Pretoria, South Africa Jo Sias Daniel - University of New Hampshire, USA Zhongyin Guo - Tongji University, Shanghai, P.R. of China Kwang W. Kim - Kangwon National University, Republic of Korea Niki Kringos - KTH Royal Institute of Technology...

  7. Travel time reliability modeling.

    Science.gov (United States)

    2011-07-01

    This report includes three papers as follows: : 1. Guo F., Rakha H., and Park S. (2010), "A Multi-state Travel Time Reliability Model," : Transportation Research Record: Journal of the Transportation Research Board, n 2188, : pp. 46-54. : 2. Park S.,...

  8. A portable high-quality random number generator for lattice field theory simulations

    International Nuclear Information System (INIS)

    Luescher, M.

    1993-09-01

    The theory underlying a proposed random number generator for numerical simulations in elementary particle physics and statistical mechanics is discussed. The generator is based on an algorithm introduced by Marsaglia and Zaman, with an important added feature leading to demonstrably good statistical properties. It can be implemented exactly on any computer complying with the IEEE-754 standard for single precision floating point arithmetic. (orig.)

  9. Analisis Perbandingan Efisiensi Penggunaan Baja Ringan Pada Tiga Jenis Tipe Rangka Atap

    OpenAIRE

    DAKHI, DICE J L

    2015-01-01

    10 0404 1097 Seiring dengan perkembangan zaman, baja ringan semakin populer digunakan pada konstruksi rangka atap. Hal ini dikarenakan baja ringan jauh lebih ekonomis dibandingkan dengan baja konvensional maupun kayu. Baja ringan juga memiliki segudang kelebihan yang sangat menguntungkan sebuah konstruksi. Tahun 2013, Badan Standar Nasional mengeluarkan SNI 7971 yaitu standar untuk perencanaan struktur baja ringan (canai dingin). Dengan adanya SNI ini, diharapkan suatu st...

  10. Perilaku Pembelian Online Produk Fashion pada Zalora Indonesia

    OpenAIRE

    Saputri, Marheni Eka

    2016-01-01

    Seiring dengan perkembangan teknologi, kemajuan berbisnis melalui internet pun semakin berkembang. Pada zaman sekarang ini, masyarakat sudah banyak yang menyukai berbelanja secara online, karena selain praktis, harga barang yang ditawarkan pun relatif murah atau sama dengan di toko konvensional. Salah satu toko online yang digemari masyarakat Indonesia adalah Zalora. Penelitian ini bertujuan untuk melihat pengaruh perilaku konsumen terhadap keputusan pembelian (studi pada konsumen Zalora Indo...

  11. The Emerging Pattern of Civil-Military Relations in Islamist States

    Science.gov (United States)

    2013-03-01

    in Turkish Politics?” Today’s Zaman, February 2, 2012, http://www.todayszaman.com/ columnist -270368-are-the-national-police- assuming-the-militarys...Egypt’s professional syndicates and student organizations. Even as Sadat and Mubarak targeted the group in periodic crackdowns, the Brothers continued to...February 2, 2012, http://www.todayszaman.com/ columnist - 270368-are-the-national-police-assuming-the-militarys-role-in-turkish- politics.html. Vatikiotis

  12. Sikap Dan Perilaku Room Boy/Room Maid Dalam Meningkatkan Prosedur Operasional Kerja Di Puri Artha Hotel Yogyakarta

    OpenAIRE

    Meliala, Eunike

    2010-01-01

    Salah satu penunjang untuk majunya dunia pariwisata adalah hotel, yaitu sebagai sarana akomodasi bagi para wisatawan, baik wisatawan nusantara maupun wisatawan mancanegara. Seiring dengan perkembangan zaman, banyak sekali hotel-hotel di Indonesia yang telah tumbuh. Oleh karena itu pihak hotel harus mampu menciptakan suasana yang dibutuhkan oleh wisatawan. Perkembangan ini harus pula diikuti oleh tenaga- tanaga yang benar-benar mengerti akan hotel secara mendasar, sehingga dapat memberikan ...

  13. Pembentukan Karakter Religius Siswa SMP Muhammadiyah 5 Tulangan Melalui Pembiasaan Morning Activity

    OpenAIRE

    Ubaidillah, Mochammad Ighfir

    2018-01-01

    Pembentukan karakter religius merupakan proses yang berlangsung seumur hidup. Pembentukan karakter merupakan hal yang sangat penting, apalagi di zaman sekarang ini, banyaknya siswa-siswa yang di setiap harinya berkata kotor atau hal-hal yang tidak pantas dikatakan oleh para siswa. Kemajuan teknologi yang tidak dibarengi dengan karakter yang religius sehingga banyak dari para siswa yang membolos saat jam pelajaran berlangsung untuk bermain playstation atau game onl...

  14. MUSEUM GEOLOGI DAN PRASEJARAH DI MAKASSAR DENGAN PENDEKATAN ARSITEKTUR HIGH TECH

    Directory of Open Access Journals (Sweden)

    Saefullah Saefullah

    2015-12-01

    Full Text Available Abstrak—Indonesia kaya akan sumber daya geologi yang terdiri dari batuan, mineral dan bahan tambang. Berbicara mengenai geologi sangat erat kaitannya dengan zaman prasejarah.karena belum ditemukannya bukti-bukti tertulis dari zaman prasejarah tersebut, keterangan mengenai zaman ini diperoleh melalui bidang-bidang seperti paleontologi, astronomi, biologi, geologi, antropologi, dan arkeologi pentingnya melestarikan dan menjaga peninggalan-peninggalan prasejarah. Sehingga akan menumbuhkan rasa tanggungjawab terhadapnya. Hal ini sejalan dengan tugas Direktorat Jendral Kebudayaan Kementrian Pendidikan dan Kebudyaaan Indonesia dalam laporan kinerjanya .yang mengemukakan bahwa sisa-sisa peninggalan sejarah penting dipelihara sebagai pelajaran hidup bagi generasi berikutnya.Tujuan penelitian menyusun suatu landasan konseptual desain perancangan Museum Geologi dan prasejarah dengan pendekatan arsitektur high-tech, menerapkan system Double fasade, Ligth Pipe dan system fotovoltaic pada bangunan, mengaplikasikan intelegent system pada utilitas pada bangunan.Hasil Laporan ini adalah mendesain bangunan museum geologi dan prasejarah di Makassar dengan pendekatan arsitektur high-tech. Kata Kunci :Museum geologi, prasejarah, high-tech Abstract-Indonesia is rich geological resources consisting of rocks, minerals and minerals. Talking about the geology is very closely related to prehistoric times because of not finding written evidence from prehistoric times, the information concerning this age obtained through fields like paleontology, astronomy, biology, geology, anthropology, and archeology importance of preserving and maintaining prehistoric relics. So will foster a sense of responsibility to it. This is in line with the duties of the Directorate General of Culture Ministry of Education and Indonesian culture in its performance report which suggested that the remains of important historical remains preserved as a living lesson for the next generation. The

  15. Guo Afr J Tradit Complement Altern Med. (2014) 11(2):411-414

    African Journals Online (AJOL)

    cadewumi

    The objective is to study the extraction process of garlic oil and its antibacterial effects. Materials and Methods: CO2 Supercritical extraction was used to investigate the optimal processing conditions for garlic oil extraction; filter paper test and suspension dilution test were applied to determine the bacteriostatic action of ...

  16. Issey Miyake näitus Pariisis

    Index Scriptorium Estoniae

    1998-01-01

    Moedisaineri Issey Miyake näitus 'Making Things' 17. jaan.-ni 1999 Pariisis Fondation Cartier's. Näitus koosneb neljast osast, teine osa 'Pleats Please Guest Series' on Miyake koostöö nelja kunstikuga: Yasumasa Morimura, Nobuyoshi Araki, Tim Hawkinsoni ja Cai Guo-Qiangiga

  17. DNA damage and decrease of cellular oxidase activity in piglet ...

    African Journals Online (AJOL)

    DNA damage and decrease of cellular oxidase activity in piglet sertoli cells exposed to gossypol. Ming Zhang, Hui Yuan, Zuping He, Liyun Yuan, Jine Yi, Sijun Deng, Li Zhu, Chengzhi Guo, Yin Lu, Jing Wu, Lixin Wen, Qiang Wei, Liqun Xue ...

  18. Thirty-seven transcription factor genes differentially respond to a ...

    Indian Academy of Sciences (India)

    and Beer 2000; Peng et al. 2004; Liu et ... distinct functions (Guo and Ecker 2004; Chen et al. 2009; ..... ethylene in the plant growth environment (Ghassemian et al. 2000). ...... Penninckx I A, Thomma B P, Buchala A, Metraux J P and Broekaert.

  19. Parental exposure to the herbicide diuron results in oxidative DNA damage to germinal cells of the Pacific oyster Crassostrea gigas.

    Science.gov (United States)

    Barranger, Audrey; Heude-Berthelin, Clothilde; Rouxel, Julien; Adeline, Béatrice; Benabdelmouna, Abdellah; Burgeot, Thierry; Akcha, Farida

    2016-02-01

    Chemical pollution by pesticides has been identified as a possible contributing factor to the massive mortality outbreaks observed in Crassostrea gigas for several years. A previous study demonstrated the vertical transmission of DNA damage by subjecting oyster genitors to the herbicide diuron at environmental concentrations during gametogenesis. This trans-generational effect occurs through damage to genitor-exposed gametes, as measured by the comet-assay. The presence of DNA damage in gametes could be linked to the formation of DNA damage in other germ cells. In order to explore this question, the levels and cell distribution of the oxidized base lesion 8-oxodGuo were studied in the gonads of exposed genitors. High-performance liquid chromatography coupled with UV and electrochemical detection analysis showed an increase in 8-oxodGuo levels in both male and female gonads after exposure to diuron. Immunohistochemistry analysis showed the presence of 8-oxodGuo at all stages of male germ cells, from early to mature stages. Conversely, the oxidized base was only present in early germ cell stages in female gonads. These results indicate that male and female genitors underwent oxidative stress following exposure to diuron, resulting in DNA oxidation in both early germ cells and gametes, such as spermatozoa, which could explain the transmission of diuron-induced DNA damage to offspring. Furthermore, immunostaining of early germ cells seems indicates that damages caused by exposure to diuron on germ line not only affect the current sexual cycle but also could affect future gametogenesis. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. Gum acacia mitigates genetic damage in adenine-induced chronic renal failure in rats.

    Science.gov (United States)

    Ali, B H; Al Balushi, K; Al-Husseini, I; Mandel, P; Nemmar, A; Schupp, N; Ribeiro, D A

    2015-12-01

    Subjects with chronic renal failure (CRF) exhibit oxidative genome damage, which may predispose to carcinogenesis, and Gum acacia (GumA) ameliorates this condition in humans and animals. We evaluated here renal DNA damage and urinary excretion of four nucleic acid oxidation adducts namely 8-oxoguanine (8-oxoGua), 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG), 8-oxoguanosine (8-oxoGuo) and 8-hydroxy-2-deoxyguanisone (8-OHdg) in rats with adenine (ADE)-induced CRF with and without GumA treatment. Twenty-four rats were divided into four equal groups and treated for 4 weeks. The first group was given normal food and water (control). The second group was given normal food and GumA (15% w/v) in drinking water. The third group was fed powder diet containing adenine (ADE) (0·75% w/w in feed). The fourth group was fed like in the third group, plus GumA in drinking water (15%, w/v). ADE feeding induced CRF (as measured by several physiological, biochemical and histological indices) and also caused a significant genetic damage and significant decreases in urinary 8-oxo Gua and 8-oxoGuo, but not in the other nucleic acids. However, concomitant GumA treatment reduced the level of genetic damage in kidney cells as detected by Comet assay and significantly reversed the effect of adenine on urinary 8-oxoGuo. Treatment with GumA is able to mitigate genetic damage in renal tissues of rats with ADE-induced CRF. © 2015 Stichting European Society for Clinical Investigation Journal Foundation.

  1. Public Diplomacy: An Alternative Diplomacy in Foreign Affairs’ Issues. Greek Public Diplomacy: Capabilities and Perspectives

    Science.gov (United States)

    2011-06-01

    146 Abdullah Bozkurt, “Democratic Deficit in Turkey,” Today’s Zaman, April 19, 2011, http://www.todayszaman.com/ columnist -241412-democratic-deficit...2010/04/09/confucius-to-their-enemies-china%E2%80%99s-investment-in- public-diplomacy/. 250 J. Nye, “The New Public Diplomacy,” Project Syndicate , Feb...255 J. Nye, “The New Public Diplomacy,” Project Syndicate , Feb 10, 2010, http://www.project- syndicate.org

  2. Translasi Pencak Silat Kedalam Film Animasi (Studi Kasus Film Kung Fu Panda)

    OpenAIRE

    Riyo Ramadhan; Hafiz Aziz Ahmad; Alvanov Z. Mansoor

    2017-01-01

    Sebagai tradisi yang telah membudaya dari sejak zaman dahulu kala, pencak silat lahir sebagai benteng kekuatan pertahanan diri sekaligus menjadi seni yang memperkaya khazanah kebudayaan bangsa Indonesia. Namun, kuatnya terpaan kebudayaan seni bela diri impor yang masuk (karate, kung fu, tae kwon do, muay thai, capoeira, dll), yang selalu didukung dengan berbagai kemasan media entertainment modern, membuat silat menjadi kalah populer bahkan di mata dan persepsi masyarakat Indonesia sendiri. Ha...

  3. Tuberculose du col utérin simulant un cancer du col utérin : à propos ...

    African Journals Online (AJOL)

    Tuberculose du col utérin simulant un cancer du col utérin : à propos d'un cas, au Centre Hospitalier Universitaire Souro Sanou de Bobo-Dioulasso, Burkina Faso. A. Dembélé, V. Konségré, E. Birba, D.A. Somé, H. Zamané, A.S. Ouédraogo, S. Kiemtoré, S. Ouattara, A. Lamien-Sanou, M. Bambara, B. Bonané/Thiéba ...

  4. Evaluation de la qualité de la tenue des dossiers médicaux des ...

    African Journals Online (AJOL)

    Evaluation de la qualité de la tenue des dossiers médicaux des patientes en gynécologie et en obstétrique dans un Centre hospitalier universitaire de référence, Burkina Faso. H. Zamané, S. Kiemtoré, I. Ouédraogo, P.D. Kaïn, Y.A. Sawadogo, S.D. Sanou, A. Ouattara, A. Dembélé, J. Lankoandé ...

  5. Casein kinase 1-Like 3 is required for abscisic acid regulation of ...

    African Journals Online (AJOL)

    Casein kinase 1-Like 3 is required for abscisic acid regulation of seed germination, root growth, and gene expression in Arabidopsis. M Wang, D Yu, X Guo, X Li, J Zhang, L Zhao, H Chang, S Hu, C Zhang, J Shi, X Liu ...

  6. African Journal of Biotechnology - Vol 12, No 49 (2013)

    African Journals Online (AJOL)

    Cloning of a vacuolar H-pryophosphatase gene from emphemeral plant Olimarabidopsis pumila whose overexpression improve salt tolerance in tobacco · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Fang Xu, Yunxia Zhao, Fang Wang, Danli Guo, Yanling Wei, ...

  7. A complete classification of minimal non-PS-groups

    Indian Academy of Sciences (India)

    Author Affiliations. Pengfei Guo1 2 Junxin Wang3 Hailiang Zhang4. School of Mathematics and Information Engineering, Lianyungang Normal College, Lianyungang 222006, People's Republic of China; Department of Civil and Architectural Engineering, City University of Hong Kong, Hong Kong 999077, People's Republic ...

  8. Effects of density and force discretizations on spurious velocities in lattice Boltzmann equation for two-phase flows

    KAUST Repository

    Xiong, Yuan; Guo, Zhaoli

    2014-01-01

    at discrete level inherited in LBE (Guo et al 2011 Phys. Rev. E 83 036707). Based on the analysis of the LBE free of checkerboard effects, in this work we further show that the force imbalance is caused by the different discretization stencils: the implicit

  9. Density functional theory, natural bond orbital and quantum theory of ...

    Indian Academy of Sciences (India)

    Density functional theory, natural bond orbital and quantum theory of atoms in molecule analyses on the hydrogen bonding interactions in tryptophan-water complexes. XIQIAN NIU, ZHENGGUO HUANG. ∗. , LINGLING MA, TINGTING SHEN and LINGFEI GUO. Tianjin Key Laboratory of Structure and Performance for ...

  10. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Yu-Song Guo Zhong-Duo Wang Cheng-Zhong Yan Yu-Lan Zhang Jin-Nan Zheng Yuan-Min Xu Tao Du Chu-Wu Liu · More Details Fulltext PDF ... Aifu Yang Dapeng Sun Shikai Liu Ying Dong Zhong Chen Zunchun Zhou · More Details Fulltext ...

  11. Iron induced RNA-oxidation in the general population and in mouse tissue

    DEFF Research Database (Denmark)

    Cejvanovic, Vanja; Kjær, Laura Kofoed; Bergholdt, Helle Kirstine Mørup

    2018-01-01

    Iron promotes formation of hydroxyl radicals by the Fenton reaction, subsequently leading to potential oxidatively generated damage of nucleic acids. Oxidatively generated damage to RNA, measured as 8-oxo-7,8-dihydroguanosine (8-oxoGuo) in urine, is increased in patients with genetic iron overloa...

  12. Influences of protective atmosphere on the characterization and ...

    Indian Academy of Sciences (India)

    tective atmosphere on the characterization and properties of the ceramics were investigated. All the ceramics showed ... Tian-Hang Zhang et al temperature and ..... Soc. 24 3731. 20. Wang Y, Zhang Y C, Hu Z J, Gao X, Guo X F and Jiang Y J.

  13. Simulation of the high-pressure phase equilibria of hydrocarbon-water/brine systems

    DEFF Research Database (Denmark)

    Zuo, You-Xiang; Stenby, Erling Halfdan; Guo, Tian-Min

    1996-01-01

    The major objectives of this work are: (1) extend the modified Patel-Teja (MPT) equation of state proposed for aqueous electrolyte systems (Zuo and Guo, 1991) to describe the liquid-liquid and vapor-liquid-liquid equilibria of hydrocarbon-water/brine systems through introducing an unconventional...

  14. Cloning, chromosome localization and features of a novel human ...

    Indian Academy of Sciences (India)

    Unknown

    Math2 may have the same functions in the nervous system. [Guo L., Jiang M., Ma Y., Cheng ... from a human foetal brain cDNA library, and its localiza- tion in the human ... using the BLASTN,. BLASTP and BLASTX algorithms on the NCBI web.

  15. Um outro mundo possível: Castoriadis e Eco na construção do imaginário

    Directory of Open Access Journals (Sweden)

    Keske, Humberto Ivan

    2003-01-01

    Full Text Available Conceito impactante, problemático, difuso, ambíguo, confuso, contestável. Refletir sobre aspectos que envolvem uma certa especulação do que possa vir a se constituir o imaginário de uma sociedade é tarefa complexa e sempre inacabada.

  16. Insect-resistance and high-yield transgenic tobacco obtained by ...

    African Journals Online (AJOL)

    hope&shola

    2010-10-04

    Oct 4, 2010 ... had great significance for agricultural sustained develop- ment. Significant advances have been made in insect- resistant gene cry engineering (Cui and Guo, 1998; Ni et al., 1998; Yan, 2003). Insect-resistant trangenic cotton, harbouring the modified, synthesized gene cry, has already been commercialized ...

  17. Optimization of cholesterol oxidase production by Brevibacterium sp ...

    African Journals Online (AJOL)

    DR. NJ TONUKARI

    When ultrasonic wave propagates in a liquid medium, it can produce cavitation and acoustic streaming. This cavi- tation generates powerful shear forces, while the acoustic streaming increases the convection of solution (Guo et ... optimal media design of the factors. MATERIALS AND METHODS. Microorganism and culture ...

  18. 76 FR 18761 - Worldwide Logistics Co., Ltd.; Possible Violations of Sections 10(a)(1) and 10(b)(2) of the...

    Science.gov (United States)

    2011-04-05

    ... FEDERAL MARITIME COMMISSION [Docket No. 11-04] Worldwide Logistics Co., Ltd.; Possible Violations... Worldwide Logistics Co., Ltd. (Worldwide) is a company based in the People's Republic of China, providing.... 228 Ning Guo Road, Yangpu District, Shanghai, PRC 200090. It is a part of the Worldwide Logistics...

  19. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    classical trajectory study of the reaction H' + HS on a new ab initio potential energy surface H2S (3A"). Jinghan Zou Shuhui Yin Dan Wu Mingxing Guo Xuesong Xu Hong Gao Lei Li Li Che. Volume 125 Issue 5 September 2013 pp 1237-1245 ...

  20. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences; Volume 122; Issue 6. Theoretical study of nucleophilic halogenalkylation of propylene oxide with halogenmethane and dihalogenmethane anion. Tao Liu Xiang-Chen Yin Guo-Dong Liu Zhang-Yu Yu. Full Papers Volume 122 Issue 6 November 2010 pp 901-909 ...

  1. Study of Cu-doping effects on magnetic properties of Fe-doped ZnO ...

    Indian Academy of Sciences (India)

    Administrator

    To take into account the random distribution of ... and spin–orbit interaction were taken into account. .... Lee H J, Jeong S-Y, Ryong Cho C and Hong Park C 2002 Appl. Phys. Lett. ... Zhang Hua-Wei, Wei Zhi-Ren, Li Zhi-Qiang and Dong Guo-Yi.

  2. SYNTHESIS AND CHARACTERISATION OF Ni0.25Co0.75Fe2O4 ...

    African Journals Online (AJOL)

    characterised for their size and structure using X-ray diffraction (XRD), high .... the sample shows broad peaks, indicating the fine crystalline nature of the particles. ... Zhao, L.J.; Zhang, H.J.; Xing,Y.; Song, S.Y.; Yu, S.Y.; Shi, W.D.; Guo, X.M.; ...

  3. Cardioprotective effect of Shenxiong glucose injection on acute ...

    African Journals Online (AJOL)

    Yu JH, Wang LY, Akinyi M, Li YH, Duan ZZ, Zhu Y, Fan. GW. Danshensu protects ... Yin Y, Guan Y, Duan JL, Wei G, Zhu YR, Quan W, Guo. C, Zhou D, Wang YH, ... HM, Han J, Kang D. Lamotrigine increases intracellular. Ca(2+) levels and ...

  4. Urinary markers of nucleic acid oxidation in Danish overweight/obese children and youths

    DEFF Research Database (Denmark)

    Kloppenborg, Julie Tonsgaard; Fonvig, Cilius Esman; Johannesen, Jesper

    2016-01-01

    study we investigated the relationships between urinary markers of nucleic acid oxidation concentrations and the degree of obesity and glucose metabolism in overweight compared to lean children. 42 (24 girls) and 35 lean (19 girls) children and adolescents were recruited from the Registry of the Danish...... or glucose metabolism in lean and obese children. However, sub-analyses adjusted for age, sex and the degree of obesity showed positive associations between the two hour glucose (2 h glucose) and the urinary markers 8-oxoGuo (p=0.02, r(2)= 0.63) and 8-oxodG (p=0.046, r(2)= 0.48) and between the insulinogenic...... index and 8-oxoGuo (p=0.03, r(2)=0.60) in the 12 obese children exhibiting impaired glucose tolerance. Excretion of the urinary markers of nucleic acid oxidation and the degree of obesity or the glucose metabolism were not associated in this study. Nevertheless, obese children with impaired glucose...

  5. An efficient chaotic maps-based authentication and key agreement scheme using smartcards for telecare medicine information systems.

    Science.gov (United States)

    Lee, Tian-Fu

    2013-12-01

    A smartcard-based authentication and key agreement scheme for telecare medicine information systems enables patients, doctors, nurses and health visitors to use smartcards for secure login to medical information systems. Authorized users can then efficiently access remote services provided by the medicine information systems through public networks. Guo and Chang recently improved the efficiency of a smartcard authentication and key agreement scheme by using chaotic maps. Later, Hao et al. reported that the scheme developed by Guo and Chang had two weaknesses: inability to provide anonymity and inefficient double secrets. Therefore, Hao et al. proposed an authentication scheme for telecare medicine information systems that solved these weaknesses and improved performance. However, a limitation in both schemes is their violation of the contributory property of key agreements. This investigation discusses these weaknesses and proposes a new smartcard-based authentication and key agreement scheme that uses chaotic maps for telecare medicine information systems. Compared to conventional schemes, the proposed scheme provides fewer weaknesses, better security, and more efficiency.

  6. Analisa Kekuatan Spiral Bevel Gear Dengan Variasi Sudut Spiral Menggunakan Metode Elemen Hingga

    OpenAIRE

    Deta Rachmat Andika; Agus Sigit Pramono

    2017-01-01

    Seiring perkembangan zaman,  teknologi roda gigi dituntut untuk mampu mentransmisikan daya yang besar dengan efisiensi yang besar pula. Pada jenis intersecting shaft gear, tipe roda gigi payung spiral (spiral bevel gear)  merupakan perkembangan dari roda gigi payung bergigi lurus (straight bevel gear). Kelebihan dari spiral bevel gear antara  lain adalah kemampuan transmisi daya dan efisiensi yang lebih besar pada geometri yang sama serta tidak terlalu berisik. Akan tetapi spiral bevel gear j...

  7. Timing Is Everything: Corticothalamic Mechanisms for Active Listening.

    Science.gov (United States)

    Linden, Jennifer F

    2017-07-05

    In this issue of Neuron, Guo et al. (2017) describe a layer 6 corticothalamic circuit that alternately drives cortical states favoring either sensory detection or discrimination. They also identify a neural mechanism that resets the phase of low-frequency cortical oscillations. Copyright © 2017. Published by Elsevier Inc.

  8. Nuclear and Mitochondrial Patterns of Population Structure in North Pacific False Killer Whales (Pseudorca crassidens)

    Science.gov (United States)

    2014-05-14

    The size of each allelic pair for each locus constituted the raw data for analyses. Samples were genetically sexed using the zinc finger (ZFX and...704. Guo SW, Thompson EA. 1992. Performing the exact test of Hardy- Weinberg proportion for multiple alleles. Biometrics . 48:361–372. Hoelzel AR

  9. A role for stomata in regulating water use efficiency in Populus x ...

    African Journals Online (AJOL)

    A role for stomata in regulating water use efficiency in Populus x euramericana and characterization of a related gene, PdERECTA. P Guo, X Xia, WL Yin. Abstract. The physiological mechanism of water use efficiency (WUE) remains elucidated, especially in poplar. We studied WUEi (instantaneous leaf transpiration ...

  10. Effects of proline on photosynthesis, root reactive oxygen species ...

    African Journals Online (AJOL)

    use

    2011-12-14

    Dec 14, 2011 ... Hoagland's nutrient solution (pH 6.3 to 6.5, EC 2.0 to 2.2 dS m-1). The nutrient .... photosynthesis system (LI-6400, LI-COR, Lincoln, NE, USA). The ..... Duan JJ, Li J, Guo SR, Kang YY (2008). ... Foster JG, Hess JL (1980).

  11. Larimichthys crocea

    Indian Academy of Sciences (India)

    farming industry (Guo et al. 2005; Wang et al. 2012). Single-nucleotide polymorphisms (SNPs) are nucleotide variations in the DNA sequence of individuals. As the ... 4.0) with a pairwise tagging approach. The genotypes of all the SNPs were determined by the MassArray system (Sequenom iPLEXassay, San Diego,. USA).

  12. 读书(英文)

    Institute of Scientific and Technical Information of China (English)

    无

    2008-01-01

    1 A Kaleidoscope of Chinese Culture《中华文化趣谈》Compiler:Zhang Yajun(Translated by Guo Hui) Publisher:Sinolingua Press This book introduces the important aspects of traditional Chinese culture,in 14 topics,including Chinese characters,numbers,animals, plants,colors,food,festivals,names and cross-cultural communication.

  13. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences; Volume 122; Issue 6. Synthesis and aggregation study of optically active tetra--[()-2-octanyloxy]-substituted copper and nickel phthalocyanines. Fang-Di Cong Gui Gao Jian-Xin Li Guo-Qing Huang Zhen Wei Feng-Yang Yu Xi-Guang Du Ke-Zhi Xing. Full Papers Volume ...

  14. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. YAN HUI GENG. Articles written in Sadhana. Volume 43 Issue 3 March 2018 pp 34. Spectral element method for wave propagation on irregular domains · YAN HUI GENG GUO LIANG QIN JIA ZHONG ZHANG · More Details Abstract Fulltext PDF. A spectral element approximation of acoustic ...

  15. Rana nigromaculata

    Indian Academy of Sciences (India)

    ONLINE RESOURCES. Development and characterization of 13 polymorphic microsatellite DNA markers for the pond green frog (Rana nigromaculata). JIE GONG1,2, HONG LAN1,2, SHENG-GUO FANG1,2 and QIU-HONG WAN1,2∗. 1College of Life Sciences, Zhejiang University, Hangzhou 310058, People's Republic of ...

  16. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. V Prasad. Articles written in Sadhana. Volume 26 Issue 1-2 February-April 2001 pp 35-57. Rapid solidification in thermal spary deposition: Microstructure and modelling · Guo-Xiang Wang V Prasad S Sampath · More Details Abstract Fulltext PDF. Mechanical, thermal, and adhesive properties of ...

  17. new polythiophenes with oligo(oxyethylene) side chains

    African Journals Online (AJOL)

    USER

    GAS. Laitao Luo*, Zhonghua Gu, Jianjun Guo. Department of Chemistry, Nangchang University, Nangchang, 330047, Jiangxi, P.R. China. (Received June 4 ... KEY WORDS: Purification of exhaust gas, Pt Rh Pd/γ-Al2O3 catalyst, Transition metals .... An ideal d% will result in a useful improvement in catalyst effectiveness.

  18. The Role of Developmental Levels in Examining the Effect of Subject Types on the Production of Auxiliary "Is" in Young English-Speaking Children

    Science.gov (United States)

    Guo, Ling-Yu; Van Horne, Amanda J. Owen; Tomblin, J. Bruce

    2011-01-01

    Purpose: Prior work (Guo, Owen, & Tomblin, 2010) has shown that at the group level, auxiliary "is" production by young English-speaking children was symmetrical across lexical noun and pronominal subjects. Individual data did not uniformly reflect these patterns. On the basis of the framework of the gradual morphosyntactic learning (GML)…

  19. Oracle Bones and Mandarin Tones: Demystifying the Chinese Language.

    Science.gov (United States)

    Michigan Univ., Ann Arbor. Project on East Asian Studies in Education.

    This publication will provide secondary level students with a basic understanding of the development and structure of Chinese (guo yu) language characters. The authors believe that demystifying the language helps break many cultural barriers. The written language is a good place to begin because its pictographic nature is appealing and inspires…

  20. The Media Do Matter: Comment on Steinberg and Monahan (2011)

    Science.gov (United States)

    Brown, Jane D.

    2011-01-01

    Steinberg and Monahan's (2011) reanalysis of the Teen Media longitudinal survey of adolescents does not meet prevailing standards for propensity score analysis and therefore does not undermine the original conclusions of the Brown, L'Engle, Pardun, Guo, Kenneavy, and Jackson (2006) analysis. The media do matter in the sexual socialization of…

  1. Heat capacity measurements on Ybx Gd2–x Zr2 O7 (x= 0, 1, 2 ...

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 32; Issue 6. Heat capacity measurements on YbGd2–Zr2O7 ( = 0, 1, 2) ceramics by differential scanning calorimetry. Zhan-Guo Liu Jia-Hu Ouyang Yu Zhou. Ceramics and Glasses Volume 32 Issue 6 December 2009 pp 603-606 ...

  2. Discovery of a Faint Eclipsing Binary GSC 02265-01456 DF Guo1, K ...

    Indian Academy of Sciences (India)

    The standard Johnson and Cousins V , and Rc filters were used during ... the expected mean square deviation and the unevenly spaced observations, it is less ..... 0.3555. 0.3555. 0.3556. 0.3556. 0.3556. 0.3556. 0.3556. 0.2. 0.3. 0.4. 0.5. 0.6.

  3. Alternatif Solusi Konflik Separatisme dalam Cerita “Calon Arang”

    Directory of Open Access Journals (Sweden)

    Sukatman Sukatman

    2016-06-01

    Full Text Available Penelitian ini bertujuan memaparkan (a cerita Calon Arang sebagai mitos otonomi, (b konteks historis cerita Calon Arang, (c tradisi otonomi “Duplang Kamal-Pandak” zaman kerajaan, dan (d implikasi cerita Calon Arang bagi solusi konflik separatisme pada abad modern. Penelitian dilaksanakan dengan menerapkan pendekatan sastra lisan. Sasaran penelitian ini adalah konsep otonomi dalam cerita “Calon Arang” dan relevansinya dengan situs sejarah Rajegwesi-Blambangan kuno di Lawang Seketheng dan situs “Duplang Kamal-Pandak” di Arjasa Jember. Data penelitian ini dikumpulkan dengan metode (a dokumentasi, (b observasi, dan (c wawancara bebas-mendalam. Analisis data dilakukan dengan menggunakan metode heuristik. Hasil penelitian menunjukkan bahwa cerita rakyat “Calon Arang” merupakan mitos ilmu pengetahuan tentang cara mengatasi konflik separatisme di Jawa pada zaman dahulu. Situs Duplang di Arjasa Jember merupakan bukti solusi konflik yang terjadi pada zaman pemerintahan raja Airlangga dengan otonomi daerah. Pengetahuan tentang otonomi dalam cerita Calon Arang relevan untuk dipertimbangkan sebagai solusi alternatif dalam menyelesaikan konflik separatisme. Kata-Kata Kunci: separatisme, otonomi, cerita “Calon Arang” Abstract: This study aims to explain (a Calon Arang as a myth of autonomy, (b the historical con-text of Calon Arang, (c the tradition of “Duplang Kamal-Pandak autonomy, and (d the implica-tions of Calon Arang as a solution to overcome separatist conflict in the modern age. This research was conducted by applying the oral literature approach. The target of this research is the concept of autonomy in the story of "Calon Arang" and its relevance to the historical sites of Rajegwesi in Lawang Seketheng and "Duplang Kamal-Pandak" in Arjasa Jember. The data were collected by (a documentation, (b observation, and (c in-depth interviews. Data analysis was performed using heuristic methods. The results showed that “Calon Arang

  4. Sınıflandırma Problemlerinin Karşılaştırılmasında ANFIS ve Basamak Korelasyon Sinir Ağının Kullanımı

    Directory of Open Access Journals (Sweden)

    Nilgün ŞENGÖZ

    2016-11-01

    Full Text Available Yapılan bu çalışmada, sınıflandırma problemleri üzerinde durulmuştur. Bu çalışma farklı yapıda olan 3 adet veri kümesinin (Tohum, Arazi Uydu Görüntüleme ve Kırmızı Şarap Kalite Değerlendirme incelenmesi ve aynı algoritmaların bu verilere uygulanması itibariyle hem başarı performansı olarak hem de zaman bakımından aralarındaki ilişkiyi gözler önüne sermektedir. Tohum verisi için yapılan karşılaştırmada Uyarlamalı ağ tabanlı bulanık çıkarım sistemi (Adaptive-Network Based Fuzzy Inference Systems-ANFIS  ile Basamak Korelasyon Sinir Ağı BKSA (Cascade Correlation Neural Network-CCNN test performans yüzdeleri %86.41 ve %88.06 olup, işlem zamanı yönünden bakıldığında ise BKSA  0.59 saniye gibi kısa bir süre içerisinde sınıflandırma yapmıştır.  Arazi Uydu Görüntüleme veri kümesinde ise test performans yüzdeleri ANFIS de %100, BKSA da ise %99.92 olmaktadır. Verinin algoritma içerisinde yaptığı işlem süreleri ise ANFIS 800 saniye, BKSA 72 saniyede tüm sınıflandırma işlemini tamamlamıştır. Son veri kümemiz ise Kırmızı Şarap Kalite değerlendirmedir ve test performans olarak bakıldığında ANFIS %99.975, BKSA ise %99.862 gibi birbirleri arasında çokta anlamlı bir fark oluşturmadığı açıkça görünmektedir. İşlem zamanı bakımından ANFIS 85.271 saniye ile BKSA metoduna göre çok hantal kalmaktadır.

  5. Anisotropic in-Plane Thermal Conductivity Observed in Few-Layer Black Phosphorus

    Science.gov (United States)

    2015-10-16

    Low, T. et al. Tunable optical properties of multilayers black phosphorus. Phys. Rev. B 90, 075434 (2014). 23. Lam, K., Dong , Z. & Guo, J. Performance...transistors. ACS Nano 9, 4138–4145 (2015). 46. Wu, J., Mao , N., Xie, L., Xu, H. & Zhang, J. Identifying the crystalline orientation of black phosphorus using

  6. Browse Title Index

    African Journals Online (AJOL)

    Items 201 - 250 of 990 ... I: Synthesis, characterization and thermal properties of a novel polyhedral cubic silsesquioxane, Abstract PDF. Enock O. Dare, Gabriel A. Olatunji, David S. .... Vol 25, No 2 (2011), Saturated properties prediction in critical region by a quartic equation of state, Abstract PDF. Yong Wang, Guo-bo Huang, ...

  7. Study of Electromagnetic Wave Absorption Properties of Carbon Nanotubes-Based Composites

    Science.gov (United States)

    2012-11-29

    Publications: [1]. G. L. Zhao, Z. Ye, Z. Li, J. A. Roberts, "New carbon nanotube-epoxy composite for dampening microwave cavity resonance", IEEE Xplore ...Nanotechnology ( IEEE - NANO), 2012 12th IEEE Conference on 20-23 Aug. 2012. [2]. Z. Li, G. L. Zhao, P. Zhang, S. Guo, J. Tang, " Thermoelectric

  8. Distribution of genes associated with yield potential and water ...

    Indian Academy of Sciences (India)

    Supplementary data: Distribution of genes associated with yield potential and water-saving in. Chinese Zone II wheat detected by developed functional markers. Zhenxian Gao, Zhanliang Shi, Aimin Zhang and Jinkao Guo. J. Genet. 94, 35–42. Table 1. Functional markers for high-yield or water-saving genes in wheat and ...

  9. Genetic fidelity in micropropagated plantlets of Ochreinauclea ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-07-06

    Jul 6, 2009 ... show the genetic similarity among the 22 plants (21 micropropagated plants and 1 donor mother plant). In the present study, ..... Determination of genetic stability in long-term micropropagated shoots of Pinus thunbergii Parl. using. RAPD markers. Plant Cell Rep. 18: 193-197. Guo WL, Gong L, Ding ZF, ...

  10. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Yuhong Zhang1 2 Keqing Lu1 Jianbang Guo1 Xuewen Long1 Xiaohong Hu1 Kehao Li1. State Key Laboratory of Transient Optics and Photonics, Xi'an Institute of Optics and Precision Mechanics, Chinese Academic of Sciences, Xi'an, 710119 China; School of Optoelectronic Engineering, Xi'an Technological University, ...

  11. Existence of positive solutions for a multi-point four-order boundary-value problem

    Directory of Open Access Journals (Sweden)

    Le Xuan Truong

    2011-10-01

    Full Text Available The article shows sufficient conditions for the existence of positive solutions to a multi-point boundary-value problem for a fourth-order differential equation. Our main tools are the Guo-Krasnoselskii fixed point theorem and the monotone iterative technique. We also show that the set of positive solutions is compact.

  12. 75 FR 4573 - Government-Owned Inventions; Availability for Licensing

    Science.gov (United States)

    2010-01-28

    ... differentiation. Inventors: Jinfang Zhu and William E. Paul (NIAID). Related Publication: J Zhu, TS Davidson, G Wei, D Jankovic, K Cui, DE Schones, L Guo, K Zhao, EM Shevach, WE Paul. Down-regulation of Gfi- 1... Standley, Ph.D.; 301-435-4074; [email protected] . Dated: January 21, 2010. Richard U. Rodriguez, Director...

  13. HTST (Yüksek Sıcaklık, Kısa Zaman Metodunda Sıcaklık Derecesi ve Depolama Zamanının Pastörize Süt Kalitesine Etkisi

    Directory of Open Access Journals (Sweden)

    Nurhan Akyüz

    2015-02-01

    Full Text Available Yaratanın yavruya en değerli armağanı olan süt, canlının ihtiyaç duyduğu çeşitli besin maddelerini yeter miktar, dengeli oran ve alınabilir formda içeren çok değerli bir besin maddesidir. Başka ürünlere çevrilmeden olduğu gibi içilmesi halinde, bu mükemmel besin maddesinden azami derecede faydalanmak mümkündür. Süt ürünlerine işlendiğinde besin değerinde farklı oranlarda kayıplar ortaya çıkmakta, çok yönlü gıda olma niteliği önemli ölçüde azalmaktadır.

  14. HTST (Yüksek Sıcaklık, Kısa Zaman) Metodunda Sıcaklık Derecesi ve Depolama Zamanının Pastörize Süt Kalitesine Etkisi

    OpenAIRE

    Akyüz, Nurhan; Çağlar, Abdullah

    2014-01-01

    Yaratanın yavruya en değerli armağanı olan süt, canlının ihtiyaç duyduğu çeşitli besin maddelerini yeter miktar, dengeli oran ve alınabilir formda içeren çok değerli bir besin maddesidir. Başka ürünlere çevrilmeden olduğu gibi içilmesi halinde, bu mükemmel besin maddesinden azami derecede faydalanmak mümkündür. Süt ürünlerine işlendiğinde besin değerinde farklı oranlarda kayıplar ortaya çıkmakta, çok yönlü gıda olma niteliği önemli ölçüde azalmaktadır....

  15. IDEOLOGICAL APPROACH TO THE TEXTS OF FOLK LITERATURE AT THE PERIOD OF USSR: IN THE CONTEXT OF ALANKAY BATIR HALK EDEBİYATI METİNLERİNE SOVYETLER BİRLİĞİ DÖNEMİNDE İDEOLOJİK YAKLAŞIM: ALANKAY BATIR ÖRNEĞİ

    Directory of Open Access Journals (Sweden)

    Bülent BAYRAM

    2009-12-01

    Full Text Available Folk Literature was under the ideologic pressure during the USSR period. From time to time it was prohibited to publish some of the literary works. Some of the works were published after they had undergone some change with the excuse that they convey idiology opposite to that of the USSR. Some of the chapters were dropped out of the literary Works: for example, this kind of changes have been done to the Epic of Alankay Batır of the Kazak Turks. Halk edebiyatı eserleri Sovyetler Birliği’nde ideolojik baskılara maruz kalmıştır. Zaman zaman bazı eserlerin yayınlanması tamamen yasaklanmıştır. Bazı eserler de Sovyet ideolojisine ters düştüğü gerekçesiyle değiştirilerek yayınlanmıştır. Bazı bölümler eserlerden çıkarılmıştır. Kazak Türklerinin Alankay Batır destanında da bu tür oynamalar görülmektedir. Elde bulunan orijinal nüsha ile yayınlanan nüsha arasındaki farklılıklar bunu açıkça göstermektedir.

  16. Diagnosis of immunodeficiency caused by a purine nucleoside phosphorylase defect by using tandem mass spectrometry on dried blood spots.

    Science.gov (United States)

    la Marca, Giancarlo; Canessa, Clementina; Giocaliere, Elisa; Romano, Francesca; Malvagia, Sabrina; Funghini, Silvia; Moriondo, Maria; Valleriani, Claudia; Lippi, Francesca; Ombrone, Daniela; Della Bona, Maria Luisa; Speckmann, Carsten; Borte, Stephan; Brodszki, Nicholas; Gennery, Andrew R; Weinacht, Katja; Celmeli, Fatih; Pagel, Julia; de Martino, Maurizio; Guerrini, Renzo; Wittkowski, Helmut; Santisteban, Ines; Bali, Pawan; Ikinciogullari, Aydan; Hershfield, Michael; Notarangelo, Luigi D; Resti, Massimo; Azzari, Chiara

    2014-07-01

    Purine nucleoside phosphorylase (PNP) deficiency is a rare form of autosomal recessive combined primary immunodeficiency caused by a enzyme defect leading to the accumulation of inosine, 2'-deoxy-inosine (dIno), guanosine, and 2'-deoxy-guanosine (dGuo) in all cells, especially lymphocytes. Treatments are available and curative for PNP deficiency, but their efficacy depends on the early approach. PNP-combined immunodeficiency complies with the criteria for inclusion in a newborn screening program. This study evaluate whether mass spectrometry can identify metabolite abnormalities in dried blood spots (DBSs) from affected patients, with the final goal of individuating the disease at birth during routine newborn screening. DBS samples from 9 patients with genetically confirmed PNP-combined immunodeficiency, 10,000 DBS samples from healthy newborns, and 240 DBSs from healthy donors of different age ranges were examined. Inosine, dIno, guanosine, and dGuo were tested by using tandem mass spectrometry (TMS). T-cell receptor excision circle (TREC) and kappa-deleting recombination excision circle (KREC) levels were evaluated by using quantitative RT-PCR only for the 2 patients (patients 8 and 9) whose neonatal DBSs were available. Mean levels of guanosine, inosine, dGuo, and dIno were 4.4, 133.3, 3.6, and 3.8 μmol/L, respectively, in affected patients. No indeterminate or false-positive results were found. In patient 8 TREC levels were borderline and KREC levels were abnormal; in patient 9 TRECs were undetectable, whereas KREC levels were normal. TMS is a valid method for diagnosis of PNP deficiency on DBSs of affected patients at a negligible cost. TMS identifies newborns with PNP deficiency, whereas TREC or KREC measurement alone can fail. Copyright © 2014 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.

  17. Journal of Genetics, Volume 81, 2002

    Indian Academy of Sciences (India)

    Unknown

    Book review: The genetics of the dog, edited by A. Ruvinsky and J. Sampson. 45. Feng, Bing-Jian see Shugart, Yin Y. Guo, Lingchen. Cloning, chromosome localization and features of a novel human gene, MATH2. 13. Hire, Ramesh S. see Misra, Hari S. Holliday, Robin. Epigenetics comes of age in the twentyfirst century. 1.

  18. Integrin-Mediated Signaling in Prostate Cancer: Role of KAI1/CD82 in Regulating Integrin and Androgen Receptor Function During Metastasis

    Science.gov (United States)

    2007-09-01

    117: 989–998. Guo X, Friess H, Graber HU, Kashiwagi M, Zimmermann A, Korc M et al. (1996). Cancer Res 56: 4876–4880. Hammond C, Denzin LK, Pan M...from NeoMarkers (Fremont, CA). Erk and p130Cas antibodies were purchased from Becton- Dickinson Transduction Labs ( Lincoln Park, NJ). Phospho-specific

  19. Numerical simulation of turbulent flow and heat transfer in parallel channel with an obstacle and verification of the field synergy principle

    Energy Technology Data Exchange (ETDEWEB)

    Tian, W.; Aye, M.; Qiu, S.; Jia, D. [Xi' an Jiaotong Univ., Dept. of Nuclear and Thermal Power Engineering, Xi' an (China)]. E-mail: wxtian_xjtu@163.com

    2004-07-01

    The field synergy principle was proposed by Guo Z. Y based on 2-D boundary laminar flow and it resulted from a second look at the mechanism of convective heat transfer. The objective of this paper is to numerically verify the applicability of this theory under turbulent flow or even with recirculating flow condition. (author)

  20. Solvothermal syntheses, crystal structures, optical and thermal ...

    Indian Academy of Sciences (India)

    compounds 1–3 exhibit optical band gaps between 2.06 and 2.35 eV. Keywords. .... under a nitrogen stream of 100 mL min. −1 . 2.3 X-ray diffraction. Single-crystal ..... Liu G N, Guo G C, Wang M S, Cai L Z and Huang J S. 2010 Five dimeric ...

  1. Pinoresinol diglucoside exhibits protective effect on dexamethasone ...

    African Journals Online (AJOL)

    Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 ... Zhan-Feng Zhang, Ji-Kang Min, Dan Wang, Jian-Ming Zhong* .... mineral density meter (Beijing Zhongxi Yuanda ..... Svedbom A, Ivergård M, Hernlund E, Rizzoli R, Kanis JA. ... Pan Y, Niu Y, Li C, Zhai Y, Zhang R, Guo X, Mei Q. Du-.

  2. Fulltext PDF

    Indian Academy of Sciences (India)

    YIMING LU1,3, PING HE2,∗, SHU-HUA MA3, GUO-ZHI LI4 and. SALEH MOBAYBEN1. 1Laboratory of Train Network, Department of Train Control Tech., Research Center of Product. & Tech., CRRC TANGSHAN CO., LTD, No. 3, Changqian Rd, Fengrun DIST, Tangshan,. Hebei, 063035, People's Republic of China. 2School ...

  3. Markers of oxidative stress in obese men with and without hypertension

    DEFF Research Database (Denmark)

    Cejvanovic, Vanja; Asferg, Camilla; Kjær, Laura Kofoed

    2016-01-01

    OBJECTIVES: The aim of our study was to investigate if the 24-hour excretion of the urinary markers for oxidative stress to DNA and RNA, measured as 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) and 8-oxo-7,8-dihydro-guanosine (8-oxoGuo), respectively, were increased in obese individuals with or ......OBJECTIVES: The aim of our study was to investigate if the 24-hour excretion of the urinary markers for oxidative stress to DNA and RNA, measured as 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) and 8-oxo-7,8-dihydro-guanosine (8-oxoGuo), respectively, were increased in obese individuals...... with or without hypertension compared to lean controls. METHODS: A total of 63 obese hypertensive men (obeseHT), 40 obese normotensive men (obeseNT) and 27 lean normotensive men (leanNT) were included in the study. Body mass index (BMI) was between 20.0 and 24.9 kg/m(2) in leanNT participants and ≥30 kg/m(2...

  4. Social media for informal science learning in China: A case study

    Directory of Open Access Journals (Sweden)

    Ke Zhang

    2014-09-01

    Full Text Available This article reports a case study on a popular informal science learning community via social media in China, named GuoKr (meaning “nutshell” in English. Data were collected through a variety of Chinese social media and social networking sites, web-based community portals, and discussion boards. Content analyses and data mining were conducted to investigate how GuoKr successfully attracted and engaged public in informal learning on scientific topics in particular. The study found three key characteristics that contributed to the success of such learning communities: (a utilizing a variety of social media to empower participants with just-in-time, accidental learning opportunities; (b daily tweets related to emerging or ongoing social events or hot topics to provide brief but intriguing knowledge “bites”, which often leads to extended readings and related resources; and (c the integration of social media and traditional face-to-face local events to engage the public in science-related learning and knowledge sharing. Practical and research implications are discussed with suggestions for future research as related to ubiquitous learning communities for informal science learning.

  5. DoD High Performance Computing Modernization Program Users Group Conference (HPCMP UGC 2011) Held in Portland, Oregon on June 20-23, 2011

    Science.gov (United States)

    2011-06-01

    time-step ~5 seconds later (Figure 10) showing how the flowfield develops. Lessons- learned from this preliminary analysis are being used to better...addition of tabs or chevrons to the nozzle rim (Liu, et al., 2009), alteration of the cross-sectional shape of the nozzle ( Tam and Zaman, 2000...control volume face using a blend of a non-dissipative central flux and a dissipative upwind flux, i.e.,: F=(1−α) Fcentral + α Fupwind where 0 < α < 1 is

  6. Runtime Systems for Extreme Scale Platforms

    Science.gov (United States)

    2013-12-01

    Programming in Java, PPPJ ’11, (New York, NY, USA), pp. 51–61, ACM, 2011. [76] Y. Guo, R. Barik , R. Raman, and V. Sarkar, “Work-first and help-first...95] R. Barik , J. Zhao, D. Grove, I. Peshansky, Z. Budimlić, and V. Sarkar, “Commu- nication Optimizations for Distributed-Memory X10 Programs,” in

  7. Development of Compositionally Graded Metallic Glass Alloys with Desirable Properties

    Science.gov (United States)

    2016-06-01

    Ma, E., Liu, H. Z., & Wen , J. (2006). Pressure tunes atomic packing in me- tallic glass. Applied Physics Letters, 88(17), 20–23. 67. Li, Y., Guo...20 and 25m deep slabs but not the 30m deep slab. The projectile stopped in the sand before reaching the 40m deep projectile. Concrete panel

  8. RNA oxidation

    DEFF Research Database (Denmark)

    Kjaer, L. K.; Cejvanovic, V.; Henriken, T.

    2015-01-01

    .9 significant hazard ratio for death compared with the quartile with the lowest 8oxoGuo excretion when adjusted for age, sex, BMI, smoker status, s-HbA1c, urine protein excretion and s-cholesterol. We conclude that it is now established that RNA oxidation is an independent risk factor for death in type 2...

  9. Co-catalyst free Titanate Nanorods for improved Hydrogen ...

    Indian Academy of Sciences (India)

    Herein, we report a simplified method for the preparation of photo-active titanate nanorods catalyst .... The TEM images were taken with Philips Technai G2 FEI F12 trans- mission electron microscope operating at 80-100 kV. Optical properties were measured in DRS ..... Chen X, Shen S, Guo L and Mao S S 2010 Chem. Rev ...

  10. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Yan-Qin Xu Guo-Yan Wei Yin Zhou Fei Ge Guang-Ming Luo · More Details Fulltext PDF. pp e25-e28. Abundance and characteristics of microsatellite markers in Gansu zokor (Eospalax cansus), a fossorial rodent endemic to the Loess plateau, China · Junhu Su Limin Hua Jing Wang Dianne M. Gleeson Yanming Wei Robyn ...

  11. and gallium-doped zinc oxide transparent conducting sol–gel thin films

    Indian Academy of Sciences (India)

    Administrator

    and 1∙76 × 10–2 Ω cm for GZO, when five multilayer coatings are made. The origin of ... indium source make its price increasing every day. On the other hand, zinc ..... Zhao Q, Xu X Y, Song X F, Zhang X Z, Yu D P, Li C P and. Guo L 2006 Appl.

  12. Signaling through the PI 3-K, Akt and SGK Pathway in Breast Cancer Progression

    Science.gov (United States)

    2013-12-01

    Moritz A, Li Y, Guo A, Villen J, Wang Y, MacNeill J, et al. Akt-RSK-S6 Kinase 552 Signaling Networks Activated by Oncogenic Receptor Tyrosine Kinases. Sci...polarity by afadin during the formation of embryoid bodies. Genes Cells. 2008;13:79– 570 90. 571 23. Su L, Hattori M, Moriyama M, Murata N, Harazaki M

  13. TUGAS DAN FUNGSI PDII-LIPI DARI MASA KE MASA

    Directory of Open Access Journals (Sweden)

    Zultanawar Zultanawar

    2011-12-01

    Full Text Available PDII-LIPI telah berusia 25 tahun pada tanggal 1 Juni 1990 ini.Sudah saatnya perlu ditinjau kembali misi atau tugas dan fungsiPDII-LIPI dalam menunjang keqiatan pembangunan, khususnya kegiatan Iptek, pendidikan dan pengembangan industri. Perlu ditinjau kembali tujuan semula mendirilcan Pusat Dokumentasi Ilmiah Nasional yang sejak tanggal 13 Januari 1986 bernama Pusat Dokumentasi dan Informasi Ilmiah. Perlu dilihat apakah tujuan semula mendirikan PDII-LIPI itu telah tercnpai, apakah telah terjadi penyesuaian- penyesuaian dan apakah tujuan semula itu perlu diubah sesuai dengan perkembangan zaman.

  14. FACEBOOK ABUSE IN PRESS AND ITS REFLECTIONS ON SOCIETY

    OpenAIRE

    Şahin, Mustafa; Sarı, Serkan Volkan

    2009-01-01

    This study aimed to investigate the incidents of abuse in Facebook with a focus on the way they are reflected in the printed media. This purpose, the study scanned the news about Facebook abuse between the years 2009-2010 in Turkish newspapers Milliyet, Sabah and Zaman. In order to analyze the collected data, “document analysis” and “content analysis” methods were used. The data revealed that those who had a Facebook account were exposed to varrying verbal, and physical abuses in some way or ...

  15. Guo et al., Afr J Tradit Complement Altern Med. (2014) 11(1):97-102

    African Journals Online (AJOL)

    cadewumi

    of diet control, drug regulation and physical exercise is the foundation and basis for controlling this disease (Lu et al., 2000; Xing ... Traditional Chinese medicine alleviates its symptoms by ... Body weight was weighed once a week, in order to.

  16. Guo et al., Afr J Tradit Complement Altern Med., (2018) 15 (1): 1-10 ...

    African Journals Online (AJOL)

    user

    2017-12-29

    Dec 29, 2017 ... PD rats exhibited left and right (especially left) lateral rotation in a head-to-tail state. ... Note: * p < 0.01, before treatment vs after treatment in the treatment .... replenish the kidney and essence and nourish the brain; Angelica, ...

  17. Modulation of epithelial sodium channel in human alveolar epithelial ...

    African Journals Online (AJOL)

    Modulation of epithelial sodium channel in human alveolar epithelial cells by lipoxin A4 through AhR-cAMP-dependent pathway. Bi-Huan Cheng1,2, Li-Wei Pan2, Sheng-Rong Zhang3, Bin-Yu Ying2, Ben-Ji. Wang2, Guo-Liang Lin2 and Shi-Fang Ding1*. 1Department of Critical Care Medicine, Qilu Hospital of Shandong ...

  18. A Conceptual Framework for Representing Human Behavior Characteristics in a System of Systems Agent-based Survivability Simulation-Intelligent Networks

    Science.gov (United States)

    2014-10-17

    2012: Leadership award, Biotechnology in Piedmond Triad. 2010-2012 Board member, Gateway University Research Park, Inc., Greensboro. 2010-2012...Carolina Biotechnology . 2010-2012 Board member, The Oak Ridge Associated Universities (ORAU) Historically Black Colleges and Universities/ Minority... Magazine , 50 (7), 121 – 127. Wei, W. & GuoSun, Z. (2010). Bayesian cognitive trust model based self-clustering algorithm for MANETs. Information

  19. Calpain-Dependent Proteolysis of the Androgen Receptor

    Science.gov (United States)

    2009-11-01

    Thompson, P.J. Goodman, C.M. Tangen, M.S. Lucia , G.J. Miller, L.G. Ford, M.M. Lieber, R.D. Cespedes, J.N. Atkins, S.M. Lippman, S.M. Carlin, A. Ryan...for the treatment of cancer. Oncogene 2007;26(22):3291-310. 30. Price DT, Della Rocca G, Guo C, Ballo MS, Schwinn DA, Luttrell LM. Activation of

  20. Zhong et al., Afr J Tradit Complement Altern Med. (2014) 11(1):1-14

    African Journals Online (AJOL)

    cadewumi

    Yunqing Zhong*1, Xiufeng Wang2, Guanglan Xu,1, Bing Mao3, Wei Zhou3, Jie Min3, Hongli Jiang3, Xiang Diao4 , ..... due to COPD exacerbations, and 1 experienced a cerebrovascular accident. ..... the body (Makino T., 2005b; Hong et al., 2011). ... An, X., Zhang, A.L., Yang, A.W., Lin, L., Wu, D., Guo, X., Shergis, J.L., Thien, ...

  1. Aeromedical Evacuation Enroute Critical Care Validation Study

    Science.gov (United States)

    2015-02-27

    percentile TP, suggesting that TPs assumed complex postures to accomplish patient care tasks. The findings suggest that ergonomic specifications...bending has been associated with back pain (Guo, 2002). Enhanced medical treatment capabilities (e.g., enroute critical care nurses [ECCN...heights, including ergonomic factors such as medic stance and stability and the medic’s ability to maneuver into challenging work angles. The light

  2. Electroactive Polyurea Bearing Oligoaniline Pendants: Electrochromic and Anticorrosive Properties

    Science.gov (United States)

    2014-12-26

    3] Cheng YJ, Yang SH, Hsu CS. Chem Rev 2009;109:5868e923. [4] Gu H, Guo J, Yan X, Wei H, Zhang X, Liu J, et al. Polymer 2014;55:4405e19. [5] Bigg DM...Reddy KN. Modern electrochemistry. New York: John Wiley and Sons; 1976. p. 622. [57] Bockris JOM, Reddy AK. Modern electrochemistry: an introduction to

  3. A system-level mechanistic investigation of traditional Chinese ...

    African Journals Online (AJOL)

    Xiao-Hong Gu* ... targets related to lung and stomach diseases were searched and screened to avoid duplication. ... Liu et al. Trop J Pharm Res, August 2017; 16(8): 1910. On account of this deficiency in knowledge, ..... Ru J, Li P, Wang J, Zhou W, Li B, Huang C, Li P, Guo Z, ... Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2013;.

  4. Calycosin regulates glucocorticoid-induced apoptosis via Nrf2/ARE ...

    African Journals Online (AJOL)

    Lifeng Fu1, WeiLiang Wu2, Jian Zhu2, Shu Qiang2, Jansong Chen2* ... Results: CA reduced the apoptosis and accumulation of ROS in DEX-treated cells. ..... its downstream effectors (Figure 5 A-C). However .... Cao J, Chen Z, Zhu Y, Li Y, Guo C, Gao K, Chen L, Shi ... Hong W. Experimental study on the effect of Calycosin.

  5. Case series

    African Journals Online (AJOL)

    abp

    3 mars 2014 ... Childs Nerv Syst. Nov 2000; 16(10-. 11):765-9. PubMed | Google Scholar. 4. Ben Becher S, Cheour M, Ben Hassine L, Hlioui S, et al. Les kystes hydatiques cerebraux chez l'enfant. Arch Péd. 1997;. 4(11):1107-1110. PubMed |Google Scholar. 5. Duishanbai S, Jiafu D, Guo H, Liu C, Liu B, et al. Intracranial.

  6. SHAPES OF JAVANESE KERIS AS A SYMBOLIC SIGN: TRANSFORMATION TOWARD THE ISLAMIC PERIOD

    Directory of Open Access Journals (Sweden)

    Widodo Ariwibowo

    2017-12-01

    orang Jawa terkait dengan konvensi-konvensi yang telah diciptakan para leluhur perlu diketahui untuk melihat secara terbalik dalam sistem produksi tanda. Pemaknaan kata kris misalnya, secara Semiotis dapat diklasifikasikan berdasarkan beberapa kata referensial di antaranya keris, dhuhung, dhuwung, curiga, wangkingan, duwung, curiga, dan katga semua menunjukkan petanda yang sama yaitu senjata tikam yang berhulu dan berwarangka. Penelitian ini menemukan terjadinya peristiwa budaya berupa penopengan (masking ideologi yang mewakili zaman tertentu, misalnya dekonstruksi pemaknaan bentuk luk keris (kemba dan rengkol menggambarkan transformasi ideologi zaman Hindhu menuju zaman Islam.

  7. TALYUMUN LUCILIA SERICATA MEIGEN 1826’NIN LARVAL GELİŞIMİ VE PMI TAHMİNİ ÜZERİNE ETKİLERİ

    Directory of Open Access Journals (Sweden)

    Ferhat ALTUNSOY

    2011-07-01

    Full Text Available Calliphoridae larvalarının adli analizlerle yaşlarının ve larval büyüme oranlarının belirlenmesi adli incelemelerde minimum ölüm zamanının ve ölüm sonrasında geçen sürenin ölüm sonrası zamanın belirlenmesinde kullanışlı delillerdir. Ancak sıcaklık, larvaların beslendiği doku tipi ve dokuların ilaç veya toksinlerle kontamine olması gibi birçok faktör yapışkan sinek larvalarının gelişimini dolayısıyla ölüm sonrası zamanın tahminini etkilemektedir. Bu çalışmada adli açıdan son derece önemli olan yapışkan sinek türü olan Lucilia sericata Meigen 1826’nın toksik ağır metal olan Talyumun farklı konsantrasyonlarındaki (0,12; 0,25; 0,50; 1 and 2 µg/g gelişimi kontrol altındaki laboratuvar koşullarında incelenmiştir. Larvaların boy, ağırlık değişimi ile larval ve pupal ölüm oranları kontrol grubu ile karşılaştırılmıştır. Sonuçlar doğrultusunda, kontrol grubu ile deney gruplarının gelişimleri arasında önemli ölçüde farkların olduğu belirlenmiştir. Kısaca, kontrol grubuna oranla, daha geç deri değiştirdikleri, maksimum uzunluğa daha geç ulaştıkları ve dozaja bağlı olarak oldukça küçük pupa oluşturdukları tespit edilmiştir. Bu sonuçlar, adli çalışmalarda, standart besi ortamında yetiştirilen larval örneklerin gelişim süreleri kullanıldığında, adli araştırmacının dokulardaki kontaminasyonu belirlemesinin önemini vurgulamaktadır.

  8. Orbital stability of solitary waves for Kundu equation

    Science.gov (United States)

    Zhang, Weiguo; Qin, Yinghao; Zhao, Yan; Guo, Boling

    In this paper, we consider the Kundu equation which is not a standard Hamiltonian system. The abstract orbital stability theory proposed by Grillakis et al. (1987, 1990) cannot be applied directly to study orbital stability of solitary waves for this equation. Motivated by the idea of Guo and Wu (1995), we construct three invariants of motion and use detailed spectral analysis to obtain orbital stability of solitary waves for Kundu equation. Since Kundu equation is more complex than the derivative Schrödinger equation, we utilize some techniques to overcome some difficulties in this paper. It should be pointed out that the results obtained in this paper are more general than those obtained by Guo and Wu (1995). We present a sufficient condition under which solitary waves are orbitally stable for 2c+sυ1995) only considered the case 2c+sυ>0. We obtain the results on orbital stability of solitary waves for the derivative Schrödinger equation given by Colin and Ohta (2006) as a corollary in this paper. Furthermore, we obtain orbital stability of solitary waves for Chen-Lee-Lin equation and Gerdjikov-Ivanov equation, respectively.

  9. Khazanah: Jeremy Bentham

    Directory of Open Access Journals (Sweden)

    Atip Latipulhayat

    2015-08-01

    Full Text Available ABSTRAK Jeremy Bentham (1748-1832 adalah seorang filosof dan ahli hukum Inggris yang dijuluki sebagai “Luther of the Legal World” (Luther dalam dunia hukum. Julukan ini meminjam ketokohan teolog Martin Luther yang melakukan reformasi terhadap doktrin-doktrin tertentu dalam ajaran Katolik. Bentham dianggap sebagai figur yang melakukan reformasi sistem hukum Inggris pada abad ke-18 yang dianggap ketinggalan zaman, dan bahkan cenderung korup. Bentham memberikan kritik tajam sekaligus tawaran reformasi terhadap sistem hukum Inggris. Utilitarianisme adalah tawaran Bentham untuk mendesain ulang sistem hukum Inggirs yang dinilainya dekaden.

  10. INTERFERENCE ERRORS STEMMING FROM MOTHER TONGUE AND ENGLISH ENCOUNTERED WHILE LEARNING ALMANCA ÖĞRENİMİNDE ANA DİLİ VE İNGİLİZCE KAYNAKLI GİRİŞİM HATALARI

    Directory of Open Access Journals (Sweden)

    Adnan OFLAZ

    2012-01-01

    Full Text Available In this study, sorts of errors caused by mother tongue and learnt language are theoretically studied in the process of learning of German. Errors of interference are evaluated by error analysis employing comparative method. In addition suggestions on how to eliminate errors in syntax, lexical and grammatical levels are proposed.From the cognitive point of view, the effects learnt knowledge in terms of proactive and retroactive stages are commonly known. Learnt knowledge has either positive or negative effect on language learning process. The recognition, classification and solution of mentioned errors due to English as a first foreign language and mother language are performed in order. As a result of errors anaylsis students produce errors because of interference caused by languages. The interlingual errors are generally seen in word order and using prepositions and forming past verb forms, adjectives, and plural forms of nouns. Lexical errors and errors in using small or capital letters are also common. The intralingual errors are widely observed while forming verbs - past and present forms Bu çalışmada ikinci yabancı dil olarak Almanca öğrenme sürecinde, daha önceden öğrenilmiş birinci yabancı dile ve ana diline bağlı olarak ortaya çıkan hata türleri öncelikle teorik olarak ayrıntılı bir şekilde açıklanmış, daha sonra karşılaştırmalı yöntem kullanılarak hata analizleriyle bu girişim hataları belirlenmiş ve değerlendirilmiştir. Ayrıca, bu çözümleme sonunda görülen söz dizimsel, sözcük bilimsel ve doğru yazım bilgisi düzlemlerindeki hataların giderilmesi için öneriler sunulmuştur.Bilişsel açıdan bakıldığı zaman, öğrenilmiş ön bilgilerin ileriye ya da geriye ket vurmasının etkilere sebep olduğu herkesçe bilinmektedir. Bu ön bilgiler öğrenmeyi ya olumlu ya da olumsuz olarak etkilemektedir. Bu çıkış noktasından hareketle, çalışmamızda, öğrenilen ilk yabancı dil

  11. Characterization of the Pathological and Biochemical Markers that Correlate to the Clinical Features of Autism

    Science.gov (United States)

    2012-08-01

    A historical review of its anatomy , physiology, cytochemistry and functional significance. Cell Mol Biol 50:675-702 Frith C (2004) Is autism a...Rocco GL, Blaess S, Guo Q, Joyner AL. Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development. Development...2004;131:5581-5590 Corrales JD, Blaess S, Mahoney EM, Joyner AL. The level of sonic hedgehog signaling regulates the complexity of cerebellar

  12. Editor's welcome, PORTAL, Vol. 4, No. 1, January 2007

    Directory of Open Access Journals (Sweden)

    Paul Allatson

    2007-01-01

    Full Text Available PORTAL Journal of Multidisciplinary International Studies enters its fourth year with the journal’s first special Chinese-language issue. Organised under the rubric of ‘The Revival of Chinese Cultural Nationalism,’ the issue has been guest edited by Dr Yingjie Guo of the Institute for International Studies, University of Technology Sydney, and features the work of scholars based in China and Australia. As Guo says in his introductory essay to the special issue, debates over cultural nationalism in China have been on the rise since the events in Tiananmen Square on June 4, 1989; indeed, the post-Tiananmen era in China may be witnessing what Guo calls an unparalleled cultural-political movement in the country’s history. The various contributors to this special issue explore the ramifications and manifestations of that broad cultural-political movement in film production, television drama, literary texts, cultural essays, regional entrepreneurship, and contemporary debates on nationalism and liberalism. This issue of PORTAL also features four non-special issue essays: a study of feminist ethics in the work of Filipino-Australian writer and dramatist Merlinda Bobis, by Dolores Herrero (Universidad de Zaragoza, Spain; a taut critique of the discourse that regards the twentieth century as the bloodiest and most atrocious in human history, by David B. MacDonald (Otago University, New Zealand; a trenchant analysis, by Ramzi Nasser and Kamal Abouchedid (Notre Dame University, Lebanon, of what the authors call the rise of “academic apartheid” in the university sector throughout the Arab world; and a fascinating exploration of the feminism and environmentalism pioneered by the Australian author, mountaineer, solicitor and Buddhist Marie Byles (1900-1979, by Allison Cadzow (University of Technology Sydney. Finally, it is a huge pleasure to also include in PORTAL’s cultural works section a selection of poems by the Chinese poet Yang Lian

  13. A Study on Expression and Tyrosine 705 phosphorylation of STAT3 ...

    African Journals Online (AJOL)

    Fas- and Bcl-2-positive cells counts on the one hand, and apoptosis-positive nerve cells count in IP and. IC, on the ..... Chen Z, Li L, Mo X, Zhang L, Xie Y, Guo Q, Wang Y. Non-invasive ... Du W, Hong J, Wang YC, Zhang YJ, Wang P, Su YW,. Lin YW, Lu R, ... Jo M, Park MH, Kollipara PS, An BJ, Song HS, Han SB,. Kim JH ...

  14. Effect of applying soybean and linseed oil and different forms of ...

    African Journals Online (AJOL)

    Katarzyna

    2014-10-29

    Oct 29, 2014 ... At the end of the ninth, eleventh and fifteenth weeks of life, blood was .... tocopherol) in a dose of 25 mg/kg (1 - 9 wk of life) and 22.5 mg/kg (10 ..... A measure of the antioxidative status of the body is the balance or ... of CAT is usually observed as a result of the generation of high ... He, X.Y. & Guo, Y., 2007.

  15. Quantitative trait locus (QTL) mapping for 100-kernel weight of ...

    African Journals Online (AJOL)

    hope&shola

    2010-12-06

    Dec 6, 2010 ... regimes. Xiao-Hong Liu1, Zu-Ping Zheng2*, Zhen-Bo Tan3, Zhong Li2 and Chuan He2 ... al., 2005; Liu et al., 2007; Wang et al., 2007a; Guo et al.,. 2008; Tang .... They could individually account for 12.63, 7.22, 4.47 and 14.47% of .... Liu ZH, Tang JH, Wei XY, Wang EL, Tian GW, Hu YM, Chen WC. (2007).

  16. Synthesis and photoluminescence study of narrow-band UVB ...

    Indian Academy of Sciences (India)

    [7] Guo C, Ding X, Seo H J, Ren Z and Bai J 2011 J. Alloys. Compd. 509 4871. [8] Zhang X, Lang H and Seo H 2011 J. Fluoresc. 21 1111. [9] Zhang Z W 2013 Ceram. Int. 39 1723. [10] Yu H 2012 J. Lumin. 132 2553. [11] Wang Q 2012 J. Lumin. 132 434. [12] Palan C, Bajaj N and Omanwar S 2016 Mater. Res. Bull. 76 216.

  17. China’s International Behavior. Activism, Opportunism, and Diversification

    Science.gov (United States)

    2009-01-01

    assessments of their national goals, see Yan Xuetong, Guoji Zhengzhi yu Zhong - guo [International Politics and China], Beijing , China: Beijing Daxue ...Decisions: Important State Strategies After 1989], Beijing , China: Zhong - yang Dangli Chubanshe, 2004, pp. 783–806. 11 Swaine and Tellis, 2000, pp. 1–20...at the Conference on East Asian Security, Beijing , China, December 15, 2003; and Wang Yi, “Quanqiuhua Jincheng Zhong de Yazhou Quyu Hezuo” [Asian

  18. Genome-Wide Analysis of Translational Control in Tuberous Sclerosis Complex

    Science.gov (United States)

    2013-07-01

    Claret, H . Al-Qassab, D. Carmignac, F. Ramadani , A. Woods, I. C. Robinson, E. Schuster, R. L. Batterham, S. C. Kozma, G. Thomas, D. Carling, K. Okkenhaug...Department of Defense, Washi ngton H eadquarters Ser vices, Directorate for Information Operations and R eports (0704-0188), 1215 Jefferson Davis...resolution using ribosome profiling. Science 324(5924):218-223. 2. Guo H , Ingolia NT, Weissman JS, & Bartel DP (2010) Mammalian microRNAs predominantly

  19. Chemical Genetic Screens for TDP-43 Modifiers and ALS Drug Discovery

    Science.gov (United States)

    2013-10-01

    red. Chlo= Chlorprothixene hydrochloride; Amo= Amoxapine; Mians = Mianserine hydrochloride; Pizo= Pizotifen malate; Pimet= Pimethixene maleate; Cloz...lobar degeneration in transgenic mice produced with TDP-43 genomic fragments. Brain. 32. Li Y, Ray P, Rao EJ, Shi C, Guo W, et al. (2010) A Drosophila...2008) Sirtuin Inhibition Protects from the Polyalanine Muscular Dystrophy Protein PABPN1. Hum Mol Genet. 36. Wang J, Farr GW, Hall DH, Li F, Furtak

  20. Positive solutions for a nonlinear periodic boundary-value problem with a parameter

    Directory of Open Access Journals (Sweden)

    Jingliang Qiu

    2012-08-01

    Full Text Available Using topological degree theory with a partially ordered structure of space, sufficient conditions for the existence and multiplicity of positive solutions for a second-order nonlinear periodic boundary-value problem are established. Inspired by ideas in Guo and Lakshmikantham [6], we study the dependence of positive periodic solutions as a parameter approaches infinity, $$ lim_{lambdao +infty}|x_{lambda}|=+infty,quadhbox{or}quad lim_{lambdao+infty}|x_{lambda}|=0. $$

  1. Kontrol Sistemleri dersi için Matlab Builder Ne ve Asp.net tabanlı web laboratuarı tasarımı

    Directory of Open Access Journals (Sweden)

    Eyüp Sönmez

    2016-08-01

    Full Text Available Mühendislik alanında sistemleri test etmek için kullanılan yazılımların öğrenilmesi ve uygulanması zaman kaybına ve asıl amaçtan uzaklaşılmasına neden olmaktadır. Bu çalışmada lisans düzeyinde okutulan Kontrol Sistemleri dersi için internet tabanlı bir arayüz tasarlanmıştır. Hazırlanan kullanıcı arayüzü ile kullanıcıların derin matematik ve programlama bilgisine ihtiyaç duymadan, sistemlerin analiz ve kontrolünü yapabilmesi; ayrıca arayüzün web tabanlı tasarlanmasıyla, yöntemin yaygınlaştırılması, zaman kaybını ortadan kaldırarak birden fazla kullanıcının eş zamanlı kullanabilmesi amaçlanmıştır. Web tabanlı arayüz tasarımı için MATLAB Web Figure ile ASP.NET platformu kullanılmıştır. Aynı zamanda arayüzde yapılan işlemlere ait pratik bilgilere de ulaşılabilmektedir. Böylece hem eğitimsel hem de akademik amaçlara uygun bir sanal laboratuar tasarımı gerçekleştirilmiştir.

  2. Lale Yetiştiriciliğinde Büyüme, Gelişme, Kalite ve Erkencilik Üzerine Gibberellik Asit (GA3 Uygulamalarının Etkileri

    Directory of Open Access Journals (Sweden)

    Gamze ZENGİN

    2016-06-01

    Full Text Available Araştırma, Cafe noir ve Conqueror lale çeşitlerinin sürme zamanı, sürme oranı, yaprak sayısı, çiçek açma zamanı, çiçek çapı, çiçek boyu, çiçeklenme süresi, çiçeklenme oranı, bitki boyu, çiçek sap uzunluğu, soğan sayısı, soğan ağırlığı üzerine farklı Gibberellik Asit (GA3 dozlarının (100, 300, 500 ve 700 ppm ve uygulama sürelerinin (30 ve 60 dakika etkilerinin belirlenmesi amacıyla cam serada yürütülmüştür. Araştırmada yetiştirme ortamı olarak %50 kompost, %30 perlit, %20 bahçe toprağı kullanılmıştır. Araştırmada, lalenin büyüme, gelişme, erkencilik ve kalite özellikleri üzerine uygulamaların ve çeşitlerin etkileri önemli bulunmuştur. Lale yetiştiriciliğinde GA3 hormon dozlarının çiçeklenme zamanı, çiçeklenme oranı, çiçek sap uzunluğu,  bitki boyu, soğan sayısı ve soğan ağırlığı bakımından; hormon uygulama sürelerinin ise bitki boyu ve soğan ağırlığı bakımından önemli olduğu saptanmıştır. Tüm uygulamalardan %99’un üzerinde bir sürme oranı elde edilmiştir. Conqueror çeşidinin Cafe noir çeşidine göre 9 ile 15 gün kadar erken sürdüğü belirlenmiştir. Uygulamalara göre ilk çiçeklenme dikimden itibaren 47 ile 65 gün içinde gerçekleşmiştir. Conqueror çeşidinde ilk çiçeklenme 13 Ocakta 60 dakika 300 ppm GA3 uygulamasından;  Cafe noir çeşidine ilk çiçeklenme 31 Ocak’ta 60 dakika 700 ppm GA3 uygulamasından elde edilmiştir.

  3. Overview of methods in RNA nanotechnology: synthesis, purification, and characterization of RNA nanoparticles.

    Science.gov (United States)

    Haque, Farzin; Guo, Peixuan

    2015-01-01

    RNA nanotechnology encompasses the use of RNA as a construction material to build homogeneous nanostructures by bottom-up self-assembly with defined size, structure, and stoichiometry; this pioneering concept demonstrated in 1998 (Guo et al., Molecular Cell 2:149-155, 1998; featured in Cell) has emerged as a new field that also involves materials engineering and synthetic structural biology (Guo, Nature Nanotechnology 5:833-842, 2010). The field of RNA nanotechnology has skyrocketed over the last few years, as evidenced by the burst of publications in prominent journals on RNA nanostructures and their applications in nanomedicine and nanotechnology. Rapid advances in RNA chemistry, RNA biophysics, and RNA biology have created new opportunities for translating basic science into clinical practice. RNA nanotechnology holds considerable promise in this regard. Increased evidence also suggests that substantial part of the 98.5 % of human genome (Lander et al. Nature 409:860-921, 2001) that used to be called "junk DNA" actually codes for noncoding RNA. As we understand more on how RNA structures are related to function, we can fabricate synthetic RNA nanoparticles for the diagnosis and treatment of diseases. This chapter provides a brief overview of the field regarding the design, construction, purification, and characterization of RNA nanoparticles for diverse applications in nanotechnology and nanomedicince.

  4. A multi-method approach for the study of lanthanum speciation in coastal and estuarine sediments

    Digital Repository Service at National Institute of Oceanography (India)

    Chakraborty, P.; Babu, P.V.R.; Sarma, V.V.

    ) in different fields (agricultural field, water treatment technology, nuclear industry, glass industry and medicine manufacturing industry) (Guo, 1987; Zhang et al. 1988; Eisenbud and Paschoa, 1989; Tribe et al. 1990; Buckingham et al. 1995) is expected... through the displacement or replacement of calcium in different cell functions and also its high affinity for phosphate groups of biological macromolecules. La 3+ ion usually prevents the influx of Ca 2+ ion and competes for available binding sites...

  5. Fourth Indo-US Workshop on Mathematical Chemistry Held in Pune, Maharastra, India on 8-12 January 2005

    Science.gov (United States)

    2005-01-12

    Galvez, University of Valencia, Valencia, Spain Xiaofeng Guo, Xinjiang University, Xinjiang, P.R. China Douglas Hawkins, University of Minnesota... Medicina Chemisry, DIvisio of2Ezpsda11 T1whrapwtica 4 Waeb Reed Anmy nstitute of Rseacb.503 Robert CMtAv MSler $p- & NM- 20910, USA. 3D pomopm zodel...Protein Ontology. HUPO 3rd World Congress 2004, Beijing, China . [7] Sidhu, A. S., T, S. Dillon, et al. (2004). Making of Protein Ontology. The Second

  6. China Report: Political, Sociological and Military Affairs.

    Science.gov (United States)

    1983-03-18

    Production Brigade of Guangbao Commune in raising chickens and rabbits in a big way. We must mobilize the commune member house- holds to utilize...The state and the commune, production brigades, and production teams operate fish farms, some of which raise fry . Why not go ahead with raising fish...Wei Xinyi, Huang Yu, Yang Jike, Guo Tixiang, Meng Fulin, Hu Tan, Zhu Nong, Fang Shiliang, Wang Zenong, Pan Ezhang, Liu Zhengwen, Chen Tianren, Ma

  7. The effect of exhaustive exercise on the concentration of purine nucleotides and their metabolites in erythrocytes

    OpenAIRE

    E Skotnicka; I Baranowska-Bosiacka; W Dudzińska; M Suska; R Nowak; K Krupecki; AJ Hłyńczak

    2008-01-01

    In this study we tried to obtain a complete overview of purine nucleotide metabolism in erythrocytes before and during an incremental, intermittent exhaustive exercise bout protocol for sportsmen (high-performance rowers) and untrained, healthy, active volunteers. Erythrocyte levels of the main nucleotides (ATP, ADP, AMP, GTP, GDP, GMP, IMP, NAD and NADP ), nucleosides (Ado, Guo, Ino) and the base Hyp were measured using the HPLC method. The parameters that can be deducted from their concent...

  8. Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia?reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice

    OpenAIRE

    Feng, Jiao; Zhang, Qinghui; Mo, Wenhui; Wu, Liwei; Li, Sainan; Li, Jingjing; Liu, Tong; Xu, Shizan; Fan, Xiaoming; Guo, Chuanyong

    2017-01-01

    Jiao Feng,1,* Qinghui Zhang,2,* Wenhui Mo,3,* Liwei Wu,1 Sainan Li,1 Jingjing Li,1 Tong Liu,1 Shizan Xu,4 Xiaoming Fan,5 Chuanyong Guo1 1Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 2Department of Clinical Laboratory, Kunshan First People’s Hospital Affiliated to Jiangsu University, Kunshan, JiangSu, 3Department of Gastroenterology, Minhang Hospital, Fudan University, Shanghai, 4Department of Gastroenter...

  9. The Role of PTHrP in Epithelial Stromal Interactions During Breast Development.

    Science.gov (United States)

    1999-07-01

    development of skeletal muscle . Development 126:1621-1629. 12. Guo L, Degenstein L, and Fuchs E. (1996) Keratinocyte growth factor is required for hair...THE MEDICAL SCIENCES 287 Parathyroid Hormone-Related Protein L ’ ^-" 7«*.* %•** ’ • ». % Figure 1. Photomicrograph of a bone biopsy specimen...evident during development when PTHrP and the PTH/PTHrP receptor genes are expressed coordinately in adjacent cells begin- ning from the late morula

  10. Annual Report to Congress: Military and Security Developments Involving the Peoples Republic of China 2016

    Science.gov (United States)

    2016-04-26

    general before he retired in 2012. Guo, who was accused in July 2015 of accepting bribes and abusing his authority over promotions, is the second...does procure the Su-35, the aircraft could enter service by 2018. In November 2015, talks to purchase 24 Su-35 fighters reportedly concluded...particularly from Russia and Ukraine. China has purchased advanced Russian defense equipment such as the SA-X-21b (S-400) SAM system, and is

  11. Vesicant Therapeutics Collaborative Core Research Program

    Science.gov (United States)

    2012-12-01

    labeled nanoparticles by this administration route. There were plentiful nanoparticles found at or near the site of injection. We are trouble-shooting...for autologous transplantation in rabbits. Cornea 19(1):65-71. 4. de la Fuente M, Seijo B, & Alonso MJ (2008) Novel hyaluronic acid-chitosan...Guo SC, et al. Engineering RNA for targeted siRNA delivery and medical application. Adv Drug Deliv Rev. 2010;62:650–66. 7. Nothisen M, Kotera M

  12. Colored ultra-thin hybrid photovoltaics with high quantum efficiency for decorative PV applications (Presentation Recording)

    Science.gov (United States)

    Guo, L. Jay

    2015-10-01

    adopted by other material systems as well. Based on these understandings, we have also developed colored perovskite PV by integrating an optical cavity with the perovskite semiconductors [4]. The principle and experimental results will be presented. 1. J. Y. Lee, K. T. Lee, S.Y. Seo, L. J. Guo, "Decorative power generating panels creating angle insensitive transmissive colors," Sci. Rep. 4, 4192, 2014. 2. K. T. Lee, J.Y. Lee, S.-Y. Seo, and L. J. Guo, "Colored ultra-thin hybrid photovoltaics with high quantum efficiency," Light: Science and Applications, 3, e215, 2014. 3. K. T. Lee, S.-Y. Seo, J.Y. Lee, and L. J. Guo, "Ultrathin metal-semiconductor-metal resonator for angle invariant visible band transmission filters," Appl. Phys. Lett. 104, 231112, (2014); and "Strong resonance effect in a lossy medium-based optical cavity for angle robust spectrum filters," Adv. Mater, 26, 6324-6328, 2014. 4. K. T. Lee, M. Fukuda, L. J. Guo, "Colored, see-through perovskite solar cells employing an optical cavity," Submitted, 2015

  13. Phylogeny and sequence variability of the Sarcocystis singaporensis Zaman and Colley, (1975) 1976 ssrDNA

    Czech Academy of Sciences Publication Activity Database

    Šlapeta, Jan Roger; Kyselová, Iveta; Richardson, A. O.; Modrý, David; Lukeš, Julius

    2002-01-01

    Roč. 88, č. 9 (2002), s. 810-815 ISSN 0932-0113 R&D Projects: GA ČR GA524/00/P015; GA AV ČR KSK6005114 Institutional research plan: CEZ:AV0Z6022909 Keywords : Sarcocystis * phylogeny * ssrDNA Subject RIV: GJ - Animal Vermins ; Diseases, Veterinary Medicine Impact factor: 1.046, year: 2002

  14. CLASSIFICAÇÃO DE NUVEM DE PONTOS LASER UTILIZANDO O CONCEITO DE ANÁLISE DE COMPONENTES PRINCIPAIS E O FATOR DE NÃO AMBIGUIDADE

    Directory of Open Access Journals (Sweden)

    Renato César dos Santos

    Full Text Available Este artigo apresenta um método que realiza a classificação automática dos pontos amostrados por um sistema de varredura a LASER aerotransportado (SVLA. Nesse método são utilizados os autovalores da matriz de variâncias e covariâncias (MVC. Para o cálculo da MVC considera-se uma vizinhança no entorno do ponto de interesse, a qual é determinada com base no conceito de entropia. A classificação é executada comparando os autovalores calculados, referentes a cada ponto e sua vizinhança, com os autovalores das estruturas ou classes predefinidas. Como medida de similaridade utiliza-se a distância euclidiana no espaço dos autovalores e, com o intuito de eliminar os pontos ambíguos, incorporou-se ao método o fator de não ambiguidade (FNA. Para avaliação do método proposto e implementado, utilizou-se um conjunto de dados LASER referente ao município de Presidente Prudente/SP, cuja densidade aproximada é de 8 pontos/m2. Os resultados mostram que mesmo diante da complexidade dos ambientes reais, algumas estruturas foram bem definidas. Com a incorporação do FNA foi possível identificar e eliminar pontos com alta probabilidade de pertencer a duas classes (pontos ambíguos, geralmente amostrados sobre vegetações, regiões com pequena densidade de pontos, próximos das regiões de bordas e sobre linhas de transmissão próximas as edificações. Por meio da avaliação quantitativa verificou-se que a incorporação do FNA ao método de classificação possibilitou diminuir a quantidade de pontos incorretamente classificados, principalmente para os maiores objetos. Além disso, foi possível verificar que o uso do FNA é interessante para áreas de vegetação, uma vez que grande parte dos pontos ambíguos são identificados.

  15. Tantangan Lembaga Keuangan Syariah dalam Menghadapi Masyarakat Ekonomi ASEAN

    Directory of Open Access Journals (Sweden)

    Budi Kolistiawan

    2017-06-01

    Full Text Available Islamic law is basically a standard concept. As the time goes by, there is an ijtihad in some aspects of life, but they do not deviate from the teaching of Islam. So Islam in solving the problem is in accordance with Islamic teaching. It is an economic system that is part of human life. Islamic economic system is expected to solve the problems of human life without deviating from Islamic law of Allah SWT. Along with the development of the era, nowadays there are many emerging Islamic-based financial institutions or commonly called as Islamic financial institutions amid community. The purpose of this study is to determine how far the reediness of Islamic financial institutions in facing the ASEAN Economic Community. The method of discussion used in this study is analysis technique based on data and references of library research.  Hukum Islam pada dasarnya merupakan konsep yang baku. Tetapi seiring berjalannya waktu, terdapat ijtihad dalam beberapa bidang kehidupan, namun tetap berada pada batasan yang tidak menyimpang dari ajaran Islam. Sehingga Islam dalam menyelesaikan masalah akan sesuai dengan perkembangan zaman. Demikian juga dengan sistem ekonomi yang merupakan bagian dari bidang kehidupan manusia. Sistem ekonomi Islam diharapkan bisa menyelesaikan permasalahan yang ada pada kehidupan manusia tanpa melanggar ketentuan hukum syariat Allah SWT. Seiring dengan perkembangan zaman, saat ini telah banyak bermunculan lembaga keuangan yang berbasis Islam atau sering disebut lembaga keuangan syariah ditengah masyarakat. Tujuan dari pembahasan ini untuk mengetahui sejauh mana kesiapan lembaga keuangan syariah menghadapi Masyarakat Ekonomi Asean. Metode pembahasan dalam artikel ini menggunakan teknik analisis berdasarkan data dan referensi kepustakaan yang ada.

  16. Perkembangan Profesional Konselor Untuk Memenuhi Kebutuhan Masyarakat Industri

    Directory of Open Access Journals (Sweden)

    Fadhila Yusri

    2013-03-01

    Full Text Available Perubahan sosial yang amat cepat dan makin kompleksnya keadaan masyarakat dewasa ini telah terjadi di seluruh belahan dunia. Perubahan itu melahirkan diferensiasi dan situasi global yang berbeda. Masyarakat industri yang tiap hari disibukkan dengan rutinitas pekerjaan dan kariernya. Bekerja di bawah tekanan dan kecemasan akan kesuksesan dalam kariernya. Bahkan banyak diantara mereka yang melupakan bahwasanya di rumah mereka mempunyai anak-anak dan keluarga yang membutuhkan perhatian lebih dan kasih sayang. Kecenderungan kriminalitas meningkat dan kenakalan remaja serta perbuatan-perbuatan yang melampaui norma-norma sosial semakin subur. Kehadiran konselor sepertinya menjawab tantangan zaman dan seiring dengan pesatnya kemajuan pasar global. Kantor berita online, careerbuilder.co.uk menulis dan menempatkan konselor dalam 10 besar profesi yang sangat dibutuhkan di dalam masyarakat saat ini. Alasannya dikemukakan bahwa tekanan hidup yang semakin meningkat membuat banyak orang menderita stres dan mengalami kecemasan berlebihan. Karena itu, tenaga konselor merupakan profesi yang dibutuhkan untuk membantu masyarakat dalam menghadapi berbagai permasalahan kehidupan di zaman globalisasi seperti saat sekarang ini. Seorang calon konselor  yang hanya cukup puas dengan kemampuan dan keahlian serta kompetensi yang sudah dikuasai secara benar dibangku perkuliahan saja tanpa membekali dengan kemampuan (skill lain. Hal ini, jelas akan menjadi pertanyaan besar, “apakah bisa menembus ketatnya persaingan dunia profesi di pasar global?”. Sementara dunia globalisasi menuntut pekerja profesional yang handal. Oleh karena itu, untuk dapat bersaing di pasar global konselor memang diharapkan untuk selalu mengembangkan kemampuan profesionalnya dibidang konseling. Arah pengembangan profesional konselor hendaknya disesuaikan dengan kebutuhan pasar global, hingga tenaga konselor dapat membantu masyarakat industri keluar dari berbagai permasalahan yang dihadapinya. Pada

  17. A Novel Extraction Approach of Extrinsic and Intrinsic Parameters of InGaAs/GaN pHEMTs

    Science.gov (United States)

    2015-07-01

    A Novel Extraction Approach of Extrinsic and Intrinsic Parameters of InGaAs/GaN pHEMTs Andong Huang1, 2, ZhengZhong2, 3, and Yongxin Guo2, 3...Suzhou Research Institute, Suzhou, China Abstract — A novel extraction approach of extrinsic and intrinsic parameters of InGaAs/GaN pHEMTs is...parameter error function. The extrinsic elements are optimized at multi-bias points and the intrinsic ones at specific bias points. Only broad ranges

  18. Algorithms for Large-Scale Astronomical Problems

    Science.gov (United States)

    2013-08-01

    Magana, Ross O’Connell, Xiaoying Xu, and Feng Yu . They are very nice and provided a lot of useful information. During these years I have worked with...Sicun Gao, Fan Guo, Yunchuan Kong, Ni Lao, Lei Li, Nan Li, Jialiu Lin, Yuefeng Lin, Xi Liu, Ning Lu, Min Luo, Kai Ren, Chao Shen, Long Qin, Huimin... Hsieh , Deborah A. Wallach, Mike Burrows, Tushar Chandra, Andrew Fikes, and Robert E. Gruber. Bigtable: A distributed storage system for structured data

  19. Some properties of focus points in one-shot decision theory

    OpenAIRE

    Guo, Peijun

    2011-01-01

    One-shot (one-time) decision problems concern the situations where a decision is experienced only once. Such one-shot decision problems are commonly encountered in business, economics and social systems. One-shot decision theory has been initially proposed by Guo [4]. The one-shot decision procedure comprises two steps. In the first step, a decision maker identifies which state of nature should be taken into account for each alternative amongst all available states of nature. These identified...

  20. Phosphoproteomic Assessment of Therapeutic Kinases for Personalized Therapy in Castration-Resistant Prostate Cancer

    Science.gov (United States)

    2016-10-01

    including bladder cancer and squamous cell carcinoma (22–24). Constitutive activation of the Notch receptors through gene rearrangements or mutations leads to...Babic I, Wei X, Huang J, Witte ON (2011) Invasive prostate carcinoma driven by c-Src and androgen receptor synergy. Cancer Res 71(3):862–872. 20. Dai B...prostate cancer cells. Cancer Res 70(13):5587–5596. 21. Guo Z, et al. (2006) Regulation of androgen receptor activity by tyrosine phosphor- ylation. Cancer

  1. Hydrothermal synthesis of porous Co(OH)2 nanoflake array film and ...

    Indian Academy of Sciences (India)

    sented discharge current and M (mg), V (V) and t (s) designate mass of ..... Chang Z R, Li H J, Tang H W, Yuan X Z and Wang H J 2009 Int. J. Hydrogen. Energy ... Interfaces 3 99. Kong L B, Liu M C, Lang J W, Liu M, Luo Y C and Kang L 2011 ... Yuan Y F, Xia X H, Wu J B, Yang J L, Chen Y B and Guo S Y 2011. Electrochim.

  2. Optimization of GaN Nanorod Growth Conditions for Coalescence Overgrowth

    Science.gov (United States)

    2016-02-04

    21, 2016 PI: Chih-Chung (C. C.) Yang, ccycc@ntu.edu.tw Graduate Institute of Photonics and Optoelectronics, National Taiwan University...nanowire light emitting diodes grown on (001) silicon by molecular beam epitaxy, Nano Lett. 10 (2010) 3355-3359. [16] W. Guo, A. Banerjee, P...Bhattacharya, B.S. Ooi, InGaN/GaN disk-in-nanowire white light emitting diodes on (001) silicon , Appl. Phys. Lett. 98 (2011) 193102. [17] H.P.T. Nguyen, M

  3. Novel in situ self-assembly nanoparticles for formulating a poorly water-soluble drug in oral solid granules, improving stability, palatability, and bioavailability

    OpenAIRE

    Dong, Xiaowei; Guo,Shujie; Pham,Kevin; Li,Diana; Penzak,Scott

    2016-01-01

    Shujie Guo,1 Kevin Pham,2 Diana Li,2 Scott R Penzak,3 Xiaowei Dong2 1State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Department of Pharmaceutical Sciences, 3Department of Pharmacotherapy, University of North Texas Health Science Center, Fort Worth, TX, USA Purpose: The purpose of this study was to develop a novel lipid-based nanotechnology to...

  4. Magnesium Matrix Composite Foams-Density, Mechanical Properties, and Applications

    Science.gov (United States)

    2012-07-24

    the USA is the 2011 Corporate Average Fuel Economy or CAFE standard. For the small car class (footprint < 3.8 m2), the current fuel economy standard...components are now available as standard components or aftermarket parts used for customization . Lightweight alloy wheels are a prominent example of...Mater. Sci. Eng. A 2001, 302, 37–45. 7. CAFE Fuel Economy. Available online: http://www.nhtsa.gov/fuel-economy (accessed on 26 June 2012). 8. Guo

  5. Bazı Isatis Türlerinin Yaprak Karakterleri ve İndikan İçeriği Üzerine Farklı Ekim Zamanlarının Etkisi

    OpenAIRE

    ÇÖMLEKCİOĞLU, Nazan; EFE, Lale; KARAMAN, Şengül

    2017-01-01

    Bu çalışmada Kahramanmaraş ekolojik koşullarında 2008ve 2009 yetiştirme sezonlarında yetiştirilen 4 Isatis türünün (Isatistinctoria, Isatis candolleana (endemik), Isatis tinctoria subsp. corymbosa ve Isatis buschiana) bazı agronomik özellikleri üzerine farklı ekimzamanlarının etkileri incelenmiştir. I.tinctoria bitkisinden yaprak verimi almak için optimum ekim zamanıilkbaharken diğer türler için sonbahar olmuştur. I. tinctoria’dan 15185 kgha-1 , I. tinctoria subsp.corymbosa’dan 15109 kg ha-1,...

  6. Perancangan dan Pembuatan Aplikasi Pengenalan Batik "Indonesiaku" Melalui Permainan Berbasis Android

    Directory of Open Access Journals (Sweden)

    Michael Cornelius Andika

    2016-11-01

    Full Text Available Game atau yang biasa disebut permainan merupakan aktivitas terstruktur yang biasanya bertujuan untuk menghibur. Seiring berkembangnya zaman tidak dapat dipungkiri bahwa game terus berkembang pesat. Game itu sendiri telah dipergunakan untuk berbagai macam jenis keperluan, termasuk pendidikan. Jenis konsol yang digunakan juga bervariasi. Di sini penulis mencoba mengembangkan suatu permainan bertema pengenalan budaya batik berjudul "Indonesiaku" dengan tujuan mengenalkan budaya batik di Indonesia yang merupakan warisan budaya bangsa. Permainan ini berbasis Android dan dikembangkan dengan framework Starling serta aplikasi Adobe Flash Builder. Pembuatan batik dalam permainan ini memiliki 4 tahap yaitu nglowong, nembok, medeli, dan nglorod. Tahap tahap tersebut digunakan sebagai simulasi saat membuat batik tulis.

  7. Etika Bisnis dalam Persektif Islam

    Directory of Open Access Journals (Sweden)

    Rodliyah Khuza'i

    2005-03-01

    Full Text Available Perdagangan merupakan aktivitas manusia untuk memenuhi kebutuhan hidupnya. Dengan berkembangnya ilmu dan teknologi, perdagangan atau perniagaan mengalami kemajuan yang pesat sesuai dengan kebutuhan dan tuntutan zaman. Perniagaan yang dilakukan manusiapun bermacam-macam, mulai dari industri kecil sampai industri besar, industri pariwisata, perusahaan jasa, real estate, usaha pertanian, dan lain-lain. Manusia ditengarai begitu cinta kepada harta, sehingga sering terjadi perselisihan, persengketaan, bahkan menimbulkan permusuhan yang sengit yang saling membahayakan. Al-Qur`an sebagai pedoman utama umat Islam telah memberikan rambu-rambu  bagaimana manusia dapat memperoleh harta, karena sesungguhnya aktivitas manusia dalam memperoleh harta tidak hanya berhubungan dengan sesama manusia, tetapi hakikatnya juga berhungan dengan Allah.

  8. KREDİ DERECELENDİRME KURULUŞLARI VE YUNANİSTAN BORÇ KRİZİ

    OpenAIRE

    BAYAR, Yılmaz

    2015-01-01

    Kredi derecelendirme kuruluşları, kredi derecelendirmeleri ile şirket veya ülkelerin kredibilitelerine ilişkin asimetrik bilginin azaltılmasına katkı sağlayarak küresel finansal sistemde önemli kuruluşlar haline gelmişlerdir. Finansal piyasaların küreselleşmesi ile birlikte kredi derecelendirme kuruluşlarının küresel finansal sistem içerisindeki etkisi de zaman içerisinde artmıştır. Bununla birlikte Asya Krizi, Küresel Finansal Kriz, Euro Bölgesi Borç Krizi gibi krizler ile Enron ve WorldCom ...

  9. ERZURUM ŞARTLARINDA DİKİM ZAMANI VE TEPE ALMANIN PATATESTE VERİM VE ÇEŞİTLİ ÖZELLİKLERİNE ETKİSİ /

    OpenAIRE

    Şenol, Sabahattin

    2010-01-01

    ÖZETErzurum Ekolojik şartlarında dikim ve tepe alma zamanmm patatesteverime ve diğer bazı agronomik karekterlere etkisini tesbitetmek için bu çalışma yapılmış, erkenci ve geç olgunlaşan 34/962 ve49/962 çeşitler bu denemeye alınmıştır. Neticede, en fazıa verim enerken dikim zamanı olarak tayin ediıen 13 Mayıs tarihinde a.ltlnmış,tepe aımanm· veya sürgün öıdürmenin önemli etkisi g&ou...

  10. Almanya İzlenimleri: Kütüphaneciler için Mesleki Deneyim ve Gelişim Fırsatı

    Directory of Open Access Journals (Sweden)

    Esmeray Karataş Ateş

    2014-06-01

    Türk kütüphanecilerin Almanya’da kendilerini geliştirecek ve farklı bakış açısı kazandıracak ne tür fırsatlar elde edebileceğini ortaya koymaktır. Bibliothek & Information International - BII (Uluslararası Kütüphane ve Enformasyon Grubu davetlisi olarak orada bulunan bizler Leipzig izlenimlerimizi, Almaya’daki kütüphaneciliği, iki ülke arasındaki ilişkileri ve her zaman başvurulabilecek burs imkanlarını sizlerle paylaşmayı amaçladık.

  11. Early diagnostic potential of APC hypermethylation in esophageal cancer

    Directory of Open Access Journals (Sweden)

    Wang B

    2018-02-01

    Full Text Available Bujiang Wang,1 Haojun Song,1 Haizhong Jiang,1 Yangbo Fu,1 Xiaoyun Ding,1 Chongchang Zhou2 1Department of Gastroenterology, Laboratory of Digestive Diseases, Ningbo First Hospital, Ningbo, 2Department of Otorhinolaryngology Head and Neck Surgery, Lihuili Hospital of Ningbo University, Ningbo, Zhejiang, People’s Republic of China Background: The hypermethylation of APC gene is observed in various cancers, including esophageal cancer (EC. However, the association between APC methylation and the initiation and progression of EC is poorly understood. Purpose and methods: The current study systematically reviewed studies on abnormal methylation of APC in EC and quantitatively synthesized 18 studies by meta-analysis involving 1008 ECs, 570 Barrett’s esophagus (BE, and 782 controls. Results: Our results showed higher methylation of APC in EC (OR = 23.33, P < 0.001 and BE (OR = 9.34, P < 0.001 than in normal controls. Whereas APC methylation in EC was similar to that in BE (P = 0.052, it was not associated with tumor stage (P = 0.204. Additionally, APC methylation was not significantly associated with overall survival (OS and relapse-free survival (RFS in patients with EC. The performance of APC methylation for the detection of EC and BE achieved areas under the receiver operating characteristic curves of 0.94 and 0.88, respectively. Conclusion: Our results imply that APC methylation detection is a potential diagnostic biomarker for EC and BE. Keywords: esophageal cancer, Barrett’s esophagus, methylation, APC

  12. An introduction to biomaterials

    CERN Document Server

    Hollinger, Jeffrey O

    2011-01-01

    Consensus Definitions, Fundamental Concepts, and a Standardized Approach to Applied Biomaterials Sciences, J.O. HollingerBiology, Biomechanics, Biomaterial Interactions: Wound Healing BiologyCutaneous Wound Pathobiology: Raison d'etre for Tissue Engineering, L.K. Macri and R.A.F. ClarkOsseous Wound Healing, A. Nawab, M. Wong, D. Kwak, L. Schutte, A. Sharma, and J.O. HollingerBiology, Biomechanics, Biomaterial Interactions: Cellular MechanicsCell and Tissue Mechanobiology, W. Guo, P. Alvarez, and Y. WangBiology, Biomechanics, Biomaterial Interactions: Materials-Host InteractionsCell-Material In

  13. Improved chaotic maps-based password-authenticated key agreement using smart cards

    Science.gov (United States)

    Lin, Han-Yu

    2015-02-01

    Elaborating on the security of password-based authenticated key agreement, in this paper, the author cryptanalyzes a chaotic maps-based password-authenticated key agreement proposed by Guo and Chang recently. Specifically, their protocol could not achieve strong user anonymity due to a fixed parameter and a malicious adversary is able to derive the shared session key by manipulating the property of Chebyshev chaotic maps. Additionally, the author also presents an improved scheme to eliminate the above weaknesses and still maintain the efficiency.

  14. Piezoelectric Resonance Defined High Performance Sensors and Modulators

    Science.gov (United States)

    2016-05-30

    19.00 20.00 30.00 Received Paper 3.00 Juan P. Tamez, Amar Bhalla, Ruyan Guo. Design and Simulation of 100 kHz and 200 kHz Tri-Phasic PZT Piezoelectric...electrooptic coefficient r_51 of tetragonal potassium lithium tantalate niobate K_095Li_005Ta_040Nb_060O_3 single crystal, Optical Materials Express, (11...Experimental Studies on Tri- Phasic PZT Piezoelectric Transducer, Ferroelectrics, (12 2014): 0. doi: 10.1080/00150193.2014.974472 Jun Li, Yang Li

  15. A novel therapeutic strategy for cartilage diseases based on lipid nanoparticle-RNAi delivery system

    OpenAIRE

    Wang, Shaowei; Wei, Xiaochun; Sun, Xiaojuan; Chen, Chongwei; Zhou, Jingming; Zhang, Ge; Wu, Heng; Guo, Baosheng; Wei, Lei

    2018-01-01

    Shaowei Wang,1 Xiaochun Wei,1 Xiaojuan Sun,1 Chongwei Chen,1 Jingming Zhou,2 Ge Zhang,3 Heng Wu,3 Baosheng Guo,3 Lei Wei1,2 1Department of Orthopaedics, The 2nd Hospital of Shanxi Medical University, Taiyuan, Shanxi, China; 2Department of Orthopaedics, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA; 3Integrated Traditional Chinese and Western Medicine, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong Background: C...

  16. Identification of New Drug Targets in Multi-Drug Resistant Bacterial Infections

    Science.gov (United States)

    2015-06-15

    Ferreras, J. A., Ryu, J. S., Di Lello, F., Tan , D. S., and Quadri, L. E. (2005) Small-molecule inhibition of siderophore biosynthesis in Mycobacterium...Lun, S., Guo, H., Adamson, J., Cisar, J. S., Davis, T. D., Chavadi, S. S., Warren, J. D., Quadri, L. E., Tan , D. S., and Bishai, W. R. (2013...e29446. doi:10.1371 /journal.pone.0029446. Therapeutic Passive Immunization March 2013 Volume 81 Number 3 iai.asm.org 921 24. Fedson DS, Nicolas -Spony

  17. Growth of Vertically Aligned ZnO Nanowire Arrays Using Bilayered Metal Catalysts

    Science.gov (United States)

    2012-01-01

    12] J. P. Liu, C. X. Guo, C. M. Li et al., “Carbon-decorated ZnO nanowire array: a novel platform for direct electrochemistry of enzymes and...cited. Vertically aligned, high-density ZnO nanowires (NWs) were grown for the first time on c-plane sapphire using binary alloys of Ni/Au or Cu/Au as...deleterious to the ZnO NW array growth. Significant improvement of the Au adhesion on the substrate was noted, opening the potential for direct

  18. iktisat ve işletmede istatistiksel anlamda indeksin önemi ve hesaplama teknikleri üzerine bir açıklama

    Directory of Open Access Journals (Sweden)

    Adnan MAZMANOĞLU

    2012-04-01

    Full Text Available Bu makalemizde doğrudan matematiksel hesaplamalarla ilgili olmakla beraber, indeks veya indeks sayılarının, bir değişkenin veya değişkenler grubunun zaman veya mekân (bölge içerisindeki değişimlerini gösteren istatistiksel bir ölçü olduğunu derinlemesine incelemeye çalışacağız (Yoğurtçugil, 1977. İşletme, İktisat ile ilgili konularda kullanılması yaygın olmakla beraber diğer alanlarda da kullanılan indeks, ekonomik yaşamın vazgeçilmez kavramları olan fiyat veya miktar karşılaştırmaları yapmak, üretim veya fiyatların zaman içindeki gelişmelerini izlemek indekslerle mümkündür. Fiyatlardaki, üretimdeki ve yaşama düzeylerindeki değişimi ölçmekten başka, farklı yıllar ya da farklı bölgeler için öğrencilerin zekâ oranlarını karşılaştırmak da indekslerle (indeks sayılarıyla yapılabilmektedir. Örneğin nasıl ki paranın satın alma gücündeki değişebilirlik nedeniyle anlamlı karşılaştırmalar yapabilmek için bazı malların fiyatları yükseltilirken bazılarınki düşürülüyorsa, bu inceleme için indeksleri bilmenin gerekli olduğunu göstereceğiz ( Akdeniz, 1984.

  19. PERKEMBANGAN PARADIGMA EPISTEMOLOGI DALAM FILSAFAT ISLAM

    Directory of Open Access Journals (Sweden)

    Fathul Mufid

    2013-06-01

    Full Text Available Abstract:    Based on historical reports, Islamic epistemology paradigm has evolved from time to time bringing different schools each other. This paper aims at revealing such differences. Methods employed are philosophical Literary Review where compiled data are analyzed inductively to formulate theoretical constructions. Research findings reveal that peripatetic philosophers highlight their mind as a dominant tool to gain knowledge using demonstrative method (burhānī.Whilst illuminative philosophers, ‘irfāniyyīn, and Sufis believe that knowledge can only be derived from mystical intuition after purification of the heart (qalb trough practices (riyā╨ah. Different schools such as ones held by Mulla Sadra and Abed al-Jabiri are based on those distinctive principles.Abstrak:      Paradigma epistemologi pemikiran Islam menurut laporan sejarah mengalami perkembangan dari zaman ke zaman, yang berbeda prinsip antara aliran yang satu dengan yang lain. Tulisan ini bertujuan untuk menguak letak perbedaan antara aliran-aliran tersebut. Metode kepustakaan filsafat dilakukan dengan analisa data induktif untuk merumuskan konstruksi teoritik.  Temuan penelitian ini adalah, bahwa para filosof Muslim Paripatetik mengedepankan akal atau rasio sebagai alat yang paling dominan untuk memperoleh pengetahuan yang benar dengan menggunakan metode demonstratif (burhānī. Sementara filosof iluminasi, kaum ‘irfānī, dan kaum sufi berprinsip bahwa pengetahuan hakiki hanya dapat diperoleh melalui intuisi-mistik, setelah melalui proses penyucian hati (qalb dengan berbagai bentuk latihan (riyā╨ah. Sementara epistemologi Mulla Sadra menggunakan tipe “hikmah”, yaitu pemaduan antara visi rasional dengan visi mistik, yang kemudian diselaraskan dengan syari’at. Epistemolog kontemporer, Abed al-Jabiri memilih epistemologi burhānī yang meyakini bahwa sumber pengetahuan adalah rasio, bukan teks atau intuisi.

  20. Budaya Hukum sebagai Faktor Pendorong Terwujudnya Reformasi Birokrasi Daerah di Indonesia

    Directory of Open Access Journals (Sweden)

    Jamiat Akadol

    2018-05-01

    Full Text Available The purpose of this research is to know the legal culture as the driving factor of the realization of regional bureaucracy reform in Indonesia. The method used is the method of normative juridical research with conceptual approaches, legislation, and case approach. Various cases of corruption and very bad service in investment activities have hindered and even damaged the image of the Indonesian nation even in today's highly dynamic world. The bureaucratic legal culture is considered the main factor causing such bad bureaucratic behavior. The legal culture of the royal heritage that is only devoted to highways is difficult to remove from bureaucratic behavior. Cultural heritage, was fertile in the new order era, even in the current reform era. Through the optimization of local culture combined with the autonomy and decentralization policy implemented with the principle of autonomy as widely as possible, it can be attempted to overcome the negative culture of bureaucratic culture into a bureaucracy that eventually can be realized good governance. Tujuan penelitian ini untuk mengetahui budaya hukum sebagai faktor pendorong terwujudnya reformasi birokrasi daerah di Indonesia. Adapun metode yang digunakan adalah metode penelitian yuridis normatif dengan pendekatan-pendekatan konseptual, perundang-undangan dan pendekatan kasus. Berbagai kasus korupsi dan pelayanan yang sangat buruk dalam kegiatan investasi telah menghambat dan bahkan merusak citra bangsa Indonesia bahkan di tingkat dunia yang sangat dinamis saat ini. Budaya hukum birokrasi dianggap sebagai faktor utama yang menyebabkan perilaku birokrasi yang buruk tersebut. Budaya hukum warisan kerajaan yang hanya mengabdi kepada raya ternyata sulit untuk dihilangkan dari perilaku birokrasi. Kultur warisan, ternyata subur di zaman orde baru, bahkan di zaman reformasi saat ini. Melalui optimalisasi kultur lokal yang dipadukan dengan kebijakan otonomi dan desentralisasi yang dilaksanakan dengan

  1. ZAMAN SERİLİ VERİLER İÇİN SERVİS TABANLI GÖRSEL YORUMLAMA ARACI

    Directory of Open Access Journals (Sweden)

    Mustafa ULVİ

    2015-05-01

    Full Text Available In statistics, signal processing, econometrics and mathematical finance, a ti me series is a sequence of data points, measured typically at successive time instants spaced at uniform time intervals. In this paper, the proposed system for time-series data visualization is a distributed lo osely coupled system enabling data and resource sharing over the Internet, for data rendering, we use Open Graphics Library (OpenGL and extend them as Web Services to be used by the third parties for visualization of time- series data.

  2. Regulation of TRAIL-Medicated Apoptosis in Prostate Cancer by Overexpression of XIAP

    Science.gov (United States)

    2005-01-01

    to a composite element, and YY1 and E1A cooperate to amplify p53 promoter activity. Mol Cell Biol 1996, 16:5933-5945 41. Guo J, Casolaro V, Seto E...Lian JB, Bushmeyer S, Seto E, Atchison ML, Penman S, van Wijnen AJ, Stein GS: Targeting of the YY1 transcription factor to the nucleolus and the...Multiple Cell Types and Tissues. The Journal of Biological Chemistry . 277: 9637-9640. 12. Lorch AS, Foust III R, Gow A, Arkoviz A, Salzman AL, Szabo

  3. Annual Staunton Hill Conference on China’s People Liberation Army (PLA) (2nd) Held in Staunton Hill, Virginia on September 6 - 8, 1991

    Science.gov (United States)

    1991-09-01

    in FBIS-CHI-91-O55. 25-26; Guo about seven percent in the military budget. From 1980 to 1989. Xiangxing and Zhu Bin, "First Generation Ship-Based...China’s Military Expenditure in the Last Ten Years," Jingji 67JFJB, 9 March 1991. Yangjiu (Economics Studies], no. 6 (20 June 1990). 77-81, 6 The...frence on the PLA 1. Given that there have been more massive Li Ruihuan, Zhu Rongji pro-reform demonstrations in a major metropolitan or Qiao Shi 1% 4

  4. A Note about the General Meromorphic Solutions of the Fisher Equation

    Directory of Open Access Journals (Sweden)

    Jian-ming Qi

    2014-01-01

    Full Text Available We employ the complex method to obtain the general meromorphic solutions of the Fisher equation, which improves the corresponding results obtained by Ablowitz and Zeppetella and other authors (Ablowitz and Zeppetella, 1979; Feng and Li, 2006; Guo and Chen, 1991, and wg,i(z are new general meromorphic solutions of the Fisher equation for c=±5i/6. Our results show that the complex method provides a powerful mathematical tool for solving great many nonlinear partial differential equations in mathematical physics.

  5. Functionally Graded Material: An overview

    CSIR Research Space (South Africa)

    Mahamood, RM

    2012-07-01

    Full Text Available -3146. [50] X. Jin, L. Wu, L. Guo, H. Yu, and Y. Sun, ?Experimental investigation of the mixed-mode crack propagation in ZrO2/NiCr functionally graded materials,? Engineering Fracture Mechanics, vol. 76(12), (2009), pp. 1800-1810. [51] Z. Cheng, D. Gao... by stable crack growth,? Engineering Fracture Mechanics, vol.72(15), (2005), pp. 2359-2372. [47] Z.-H. Jin, and R.H. Dodds Jr, ?Crack growth resistance behavior of a functionally graded material: computational studies,? Engineering Fracture Mechanics...

  6. Femtosecond Laser Microstructuring and Chalcogen Inclusion in Silicon

    Science.gov (United States)

    2011-02-12

    photodetectors. The authors would like to acknowledge Dr. Hao Chen, Ariane E. Beck , Dr. Shuling Wang, and Dr. Gauri V. Karve for helpful discussions. This...2002. 3Z. Huang, J. Oh, and J. C. Campbell, Appl. Phys. Lett. 85, 2386 2004. 4Z. Huang, N. Kong, X. Guo, N. Duan, M. Liu, A. L. Beck , S. K...surfaces microstructured in air," Appl. Phys. Lett. 81, 1999-2001 (2002) [doi:10.1063/1.1504868]. [49] S. Tong, X. N. Liu, T. Gao, X. M. Baa , Y

  7. The General Traveling Wave Solutions of the Fisher Equation with Degree Three

    Directory of Open Access Journals (Sweden)

    Wenjun Yuan

    2013-01-01

    degree three and the general meromorphic solutions of the integrable Fisher equations with degree three, which improves the corresponding results obtained by Feng and Li (2006, Guo and Chen (1991, and Ağırseven and Öziş (2010. Moreover, all wg,1(z are new general meromorphic solutions of the Fisher equations with degree three for c=±3/2. Our results show that the complex method provides a powerful mathematical tool for solving a large number of nonlinear partial differential equations in mathematical physics.

  8. RNA İNTERFERANS (RNAİ)

    OpenAIRE

    GÜNDOĞDU, Ramazan; ÇELİK, Venhar

    2009-01-01

    RNA interferans, uygun çift zincirli RNA’nın hücreye girdiği zaman, endojenik komplementer mRNA dizisinin parçalanmasına yol açan, transkripsiyon sonrası gen susturma mekanizmasıdır. RNA interferans, Dicer adı verilen bir RNase III enzimi tarafından çift zincirli RNA’nın küçük engelleyici RNA’lara (siRNA) kesilmesi ile başlamaktadır. Bu siRNA’lar daha sonra, bir multiprotein-RNA nükleaz kompleksi olan, RNA- indükleyici baskılama kompleksine (RISC) bağlanır. RISC, siRNA’ları komplementer mRNA’...

  9. HALKLA İLİŞKİLERDE İMAJ BAĞLAMINDA TÜKETİCİNİN ALGISI: VOLKSWAGEN EMİSYON HABERİNİN İNCELENMESİ

    OpenAIRE

    BAYINDIR, Berkan

    2017-01-01

    Bu çalışmamızda, Volkswagen firması hakkında 18 Eylül 2015 tarihinde ortaya çıkan firmanın çeşitli otomobil modellerinin dizel motorlu versiyonlarında, emisyon oranları ile ilgili hileli yönlendirme (manipülasyon) yaptıklarına dair Amerika kaynaklı haberin yerli ve yabancı basında yayınlanmasından sonra, ülkemizdeki Volkswagen marka otomobil kullanıcıları veya markaya ilgi duyan hedef kitledeki ilk bir aylık zaman dilimindeki yansımaları incelenecektir. Firmanın köklü bir otomobil markası olm...

  10. TAM MALİYET VE NORMAL MALİYET YÖNTEMLERİNİN UFRS (TFRS) VE BOBİ FRS’DEKİ DÜZENLEMELER ÇERÇEVESİNDE İNCELENMESİ

    OpenAIRE

    Gökçen, Gürbüz; ÖZTÜRK, Erkan

    2018-01-01

    Tam maliyet yöntemi güvenilir bir ölçümlemearacı olarak kabul edilmesi nedeniyle uzun yıllar boyunca birçok işletmetarafından kullanılmıştır. Bununla birlikte, maliyet ölçümlemesinde yöntemineksik yanları zaman içerisinde tespit edilmiş ve alternatif yöntemlergeliştirilmiştir. Günümüzde Uluslararası Finansal Raporlama Standartları (UFRS)setinde ve bu setin Türkçe tercümesi olan Türkiye Finansal RaporlamaStandartları (TFRS) setinde maliyet ölçümlemesinin tam maliyet yöntemi yerinenormal maliye...

  11. Protective effect of 4-coumaric acid from UVB ray damage in the rabbit eye

    International Nuclear Information System (INIS)

    Lodovici, Maura; Caldini, Silvia; Morbidelli, Lucia; Akpan, Victor; Ziche, Marina; Dolara, Piero

    2009-01-01

    UV-induced oxidation damage seems to play a major role in a number of specific pathological conditions of intraocular tissues, such as cataract formation and retinal degeneration. Therefore, antioxidant and/or scavenger compounds might protect the eyes from UV-induced cellular damage. We previously reported that 4-coumaric acid (4-CA) is able to protect rabbit corneal-derived cells (SIRC) from UVB-induced oxidation damage. In this study we evaluated the protective effect of 4-CA against UVB-induced cell damage in rabbit cornea in vivo. Twelve male New Zealand albino rabbits were used; four rabbits were used as a control and received vehicle in one eye and 4-CA acid in the contralateral eye; eight rabbits were exposed to UVB rays (79.2 mJ/cm 2 ) and three days before to UV exposure each animal received 1 drop/day of vehicle in one eye and 1 drop/day of vehicle containing 4-CA (164 ng) in the contralateral eye. Corneal and sclera tissues were removed and 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo) levels were measured. Superoxide dismutase (SOD) and xanthine oxidase (XO) activities were determined in aqueous humour. UVB-induced vessel hyper-reactivity was strongly reduced at 4 and 24 h after UVB exposure after local treatment with 4-CA, 8-oxodGuo levels, a marker of oxidative DNA damage, were significantly increased (P < 0.05) in sclera and cornea by UVB irradiation, but when 4-CA was administered to the conjunctiva in a buffered solution once a day for 3 d before and 6 d after UVB exposure, levels of 8-oxodGuo were similar to controls and significantly reduced (P < 0.05) compared to UVB-treated corneas. XO activity in the aqueous humour was significantly increased. The administration of 4-CA for 3 d before and 6 d after UVB irradiation induced a small but significant (P < 0.05) reduction of XO compared with control eyes. Our results indicate that the administration of 4-CA protects eye tissues, thus reducing the harmful effect of UVB radiation at low

  12. Exploration of the Singlet O2 Oxidation of 8-Oxoguanine by Guided-Ion Beam Scattering and Density Functional Theory: Changes of Reaction Intermediates, Energetics, and Kinetics upon Protonation/Deprotonation and Hydration.

    Science.gov (United States)

    Sun, Yan; Lu, Wenchao; Liu, Jianbo

    2017-02-09

    8-Oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo) is one of the most common DNA lesions resulting from reactive oxygen species and ionizing radiation, and is involved in mutagenesis, carcinogenesis, and cell death. Notably, 8-oxodGuo is more reactive toward singlet (a 1 Δ g ) O 2 than the undamaged guanosine, and the lesions arising from the secondary oxidation of 8-oxodGuo are more mutagenic. Herein the 1 O 2 oxidation of free base 8-oxoguanine (8-oxoG) was investigated at different initial conditions including protonated [8-oxoG + H] + , deprotonated [8-oxoG - H] - , and their monohydrates. Experiment was carried out on a guided-ion beam scattering tandem mass spectrometer. Measurements include the effects of collision energy (E col ) on reaction cross sections over a center-of-mass E col range from 0.1 to 0.5 eV. The aim of this study is to quantitatively probe the sensitivity of the early stage of 8-oxoG oxidation to ionization and hydration. Density functional theory and Rice-Ramsperger-Kassel-Marcus calculations were performed to identify the intermediates and the products along reaction pathways and locate accessible reaction potential energy surfaces, and to rationalize reaction outcomes from energetic and kinetic points of view. No product was observed for the reaction of [8-oxoG + H] + ·W 0,1 (W = H 2 O) because insurmountable barriers block the addition of 1 O 2 to reactant ions. Neither was [8-oxoG - H] - reactive with 1 O 2 , in this case due to the rapid decay of transient intermediates to starting reactants. However, the nonreactivity of [8-oxoG - H] - was inverted by hydration; as a result, 4,5-dioxetane of [8-oxoG - H] - was captured as the main oxidation product. Reaction cross section for [8-oxoG - H] - ·W + 1 O 2 decreases with increasing E col and becomes negligible above 0.3 eV, indicating that the reaction is exothermic and has no barriers above reactants. The contrasting oxidation behaviors of [8-oxoG + H] + ·W 0,1 and [8-oxoG - H] - ·W 0

  13. Highly effective photothermal chemotherapy with pH-responsive polymer-coated drug-loaded melanin-like nanoparticles

    Directory of Open Access Journals (Sweden)

    Zhang C

    2017-03-01

    Full Text Available Chengwei Zhang,1 Xiaozhi Zhao,1 Suhan Guo,2 Tingsheng Lin,1 Hongqian Guo1 1Department of Urology, Nanjing Drum Tower Hospital, Medical School of Nanjing University, Institute of Urology, Nanjing University, 2School of Public Health, Nanjing Medical University, Nanjing, People’s Republic of China Abstract: Dopamine is a neurotransmitter commonly used in clinical treatment. Polydopamine (PDA has excellent histocompatibility and biosafety and can efficiently convert near-infrared reflection (NIR to thermal energy. In this study, PDA was used as a promising carrier, and pH-responsive polymer-coated drug-loaded PDA nanoparticles (NPs; doxorubicin@poly(allylamine-citraconic anhydride [Dox@PAH-cit]/PDA NPs were developed. As expected, the Dox@PAH-cit/PDA NPs exhibited excellent photothermal efficiency. In addition, at a low pH condition, the loaded Dox was released from the NPs due to the amide hydrolysis of PAH-cit. Upon NIR exposure (808 nm, the temperature of the NP solution rapidly increases to kill tumor cells. Compared with unbound chemotherapy drugs, the NPs have a stronger cell uptake ability. In vivo, the PDA NPs were able to efficiently accumulate at the tumor location. After intravenous administration and NIR exposure, tumor growth was significantly inhibited. In summary, the present investigation demonstrated that the Dox@PAH-cit/PDA NPs presented highly effective photothermal chemotherapy for prostate cancer. Keywords: prostate cancer, photothermal therapy, near-infrared reflection, dopamine, PAH-cit, drug delivery 

  14. The Eddington Ratio of H2O Maser Host AGN Q. Guo1, J. S. Zhang2 ...

    Indian Academy of Sciences (India)

    tion rate and on the efficiency for converting gravitational energy into radiation. The. Eddington ratio, i.e., ratio of the bolometric luminosity and Eddington luminosity, is very important to constrain predictions of theoretical models. Observations demon- strate that most of the H2O maser spots are located in the nuclear region ...

  15. Chemical characterization of a marine conditioning film

    Digital Repository Service at National Institute of Oceanography (India)

    Garg, A.; Jain, A.; Bhosle, N

    Biology 2, 228-235. Hung, C.C., Guo, L., Santschi, P.H., Quiroz, N.A., Haye, J.M., 2003. Distribution of carbohydrate species in the Gulf of Mexico. Marine Chemistry 18, 119-135. Little, B.J., Zsolnay, Z.A., 1985. Chemical fingerprinting of adsorbed...-110. Bhosle, N.B., Garg, A., Fernandes, L., Citon, P., 2005. Dynamics of amino acids in the conditioning film developed on glass panels immersed in surface seawaters of the Dona Paula Bay. Biofouling 21 (2), 99-107. Borch, N.H., Kirchmen, D.L., 1997...

  16. Additional New Minor Cucurbitane Glycosides from Siraitia grosvenorii

    Directory of Open Access Journals (Sweden)

    Indra Prakash

    2014-03-01

    Full Text Available Continuous phytochemical studies of the crude extract of Luo Han Guo (Siraitia grosvenorii furnished three additional new cucurbitane triterpene glycosides, namely 11-deoxymogroside V, 11-deoxyisomogroside V, and 11-deoxymogroside VI. The structures of all the isolated compounds were characterized on the basis of extensive NMR and mass spectral data as well as hydrolysis studies. The complete 1H- and 13C-NMR spectral assignments of the three unknown compounds are reported for the first time based on COSY, TOCSY, HSQC, and HMBC spectroscopic data.

  17. Cryptanalysis of Multiparty Quantum Secret Sharing of Quantum State Using Entangled States

    International Nuclear Information System (INIS)

    Su-Juan, Qin; Qiao-Yan, Wen; Fu-Chen, Zhu

    2008-01-01

    Security of a quantum secret sharing of quantum state protocol proposed by Guo et al. [Chin. Phys. Lett. 25 (2008) 16] is reexamined. It is shown that an eavesdropper can obtain some of the transmitted secret information by monitoring the classical channel or the entire secret by intercepting the quantum states, and moreover, the eavesdropper can even maliciously replace the secret message with an arbitrary message without being detected. Finally, the deep reasons why an eavesdropper can attack this protocol are discussed and the modified protocol is presented to amend the security loopholes

  18. QSAR Classification Model for Antibacterial Compounds and Its Use in Virtual Screening

    Science.gov (United States)

    2012-09-26

    pertussis (290 000), and tetanus (210 000).1 Considering this staggering number of deaths, there should be a lucrative market for drug therapies for...e Th r e a t R edu c t i o n Ag en c y G r a n t Journal of Chemical Information and Modeling Article dx.doi.org/10.1021/ci300336v | J. Chem. Inf...15, 2012). (32) Knox, C.; Law, V.; Jewison, T.; Liu, P.; Ly, S.; Frolkis, A.; Pon, A.; Banco , K.; Mak, C.; Neveu, V.; Djoumbou, Y.; Eisner, R.; Guo, A

  19. Effect of Flake Thickness on Coercivity of Nanocrystalline SmCo5 Bulk Prepared from Anisotropic Nanoflake Powder (Postprint)

    Science.gov (United States)

    2016-08-23

    s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution 3.0 Unported License. [http://dx.doi.org...281, 23 (1998). 5 J. Zhou, R. Skomski, and D. J. Sellmyer, J. Appl . Phys. 93, 6495 (2003). 6 M. Yue, J. H. Zuo, W. Q. Liu, W. C. Lu, D. T. Zhang, J...X. Zhang, Z. H. Guo, and W. Li, J. Appl . Phys. 109, 07A700 (2011). 7 A. M. Gabay, M. Marinescu, J. F. Liu, and G. C. Hadjipanayis, J. Magn. Magn

  20. Importância da região AV3V para as respostas pressoras produzidas pela ativação de áreas bulbares.

    OpenAIRE

    Alexandre Antonio Vieira

    2005-01-01

    Respostas cardiovasculares podem ser integradas em diferentes níveis do sistema nervoso central (SNC). Em particular, o hipotálamo e o bulbo estão muito envolvidos com o controle de respostas autonômicas, entre as quais estão as repostas cardiovasculares. No bulbo estão vários núcleos importantes para o controle cardiovascular como o núcleo do trato solitário (NTS), as áreas rostroventrolateral (RVL) e caudoventrolateral (CVL) e o núcleo ambíguo. Um circuito envolvendo essas...

  1. Effect of mechanical milling and cold pressing on co power

    CSIR Research Space (South Africa)

    Bolokang, AS

    2012-01-01

    Full Text Available , pp. 2781?2786, 1984. [11] E. A. Owen and D. Madoc Jones, ?Effect of grain size on the crystal structure of cobalt,? Proceedings of the Physical Society B, vol. 67, no. 6, article 302, pp. 456?466, 1954. [12] A. S. Bolokang, M. J. Phasha, C.... Patriarche, E. Le Bourhis, M. M. O. Khayyat, and M. M. Chaudhri, ?Indentation-induced crystallization and phase transformation of amorphous germanium,? Journal of Applied Physics, vol. 96, no. 3, pp. 1464?1468, 2004. [23] G. J. Fan, F. Q. Guo, Z. Q. Hu, M...

  2. Triazole derivatives with improved in vitro antifungal activity over azole drugs

    Directory of Open Access Journals (Sweden)

    Yu S

    2014-04-01

    Full Text Available Shichong Yu,1,* Xiaoyun Chai,1,* Yanwei Wang,1 Yongbing Cao,2 Jun Zhang,3 Qiuye Wu,1 Dazhi Zhang,1 Yuanying Jiang,2 Tianhua Yan,4 Qingyan Sun11Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China; 2Drug Research Center, School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China; 3Overseas Education Faculty of the Second Military Medical University, Shanghai, People's Republic of China; 4Department of Pharmacology, School of Pharmacy, China Pharmaceutical University, Nanjing, People's Republic of China*These authors contributed equally to this workAbstract: A series of triazole antifungal agents with piperidine side chains was designed and synthesized. The results of antifungal tests against eight human pathogenic fungi in vitro showed that all the compounds exhibited moderate-to-excellent activities. Molecular docking between 8d and the active site of Candida albicans CYP51 was provided based on the computational docking results. The triazole interacts with the iron of the heme group. The difluorophenyl group is located in the S3 subsite and its fluorine atom (2-F can form H-bonds with Gly307. The side chain is oriented into the S4 subsite and formed hydrophobic and van der Waals interactions with the amino residues. Moreover, the phenyl group in the side chain interacts with the phenol group of Phe380 through the formation of π–π face-to-edge interactions.Keywords: synthesis, CYP51, molecular docking, azole agents

  3. Sünnet Fobisi Nedeniyle Üretral Fistül Oluşumu

    OpenAIRE

    Kılıç, Azize; Kılıç, Ali

    2000-01-01

    Bütün dünyada yaygın olarak kullanılan sünnetin, üriner trakt enfeksiyonları, cinsel yolla bulaşan hastalıklar, penil ve servikal kanserler gibi problemlerde olumlu etkileri vardır.Ülkemizde yaygın olarak kullanılan bu küçük cerrahi müdahalenin çocuklarda oluşturacğı korku stresi kaçınılmazdır. Bu stresi yoğun yaşayan ve kendisine ciddi boyutta hayati ve cinsel nlamda zarar verebilecek bir olgu ailesinin zamanında müdhelesiyle olayı daha az önemli olan bir komplikasyon olan üretral fistülle t...

  4. MgB2 Süperiletken Tellerde Alternatif Akım Kaybı ve Akı Perçinleme Mekanizmaları

    OpenAIRE

    SAFRAN, Serap

    2010-01-01

    Bu çalışmada çok filamanlı Bi-2223/Ag şerit ve farklı kılıf malzemesine sahip tek ve çok filamanlı MgB2 teller için alternatif akım (AA) kaybı deneysel olarak ölçüldü.  Bu süperiletkenler için teorik olarak manyetik alan şerit yüzeyine dik olarak uygulandığı zaman AA kayıp hesaplanarak deneysel sonuçlarla karşılaştırıldı. Deneysel verilerle hesaplamalar arasında iyi bir uyum gözlendi. Hesaplamalar için ticari sonlu elemanlar yazılımı (Comsol Multiphysi...

  5. Kauçuk sektörü Poka-Yoke uygulaması

    OpenAIRE

    Pekin, Engin; Çil, İbrahim

    2015-01-01

    Bir üretim tesisinde her zaman gözlemlenmesi ve ortadan kaldırılması gereken konuların başında kalite problemleri vehatalı ürünler gelmektedir. Üretimde insan faktörü ise hatalı ürün ve kalite problemlerinin en önemli kök nedenlerindenbiri olarak değerlendirilmektedir. İlk olarak Toyota’da mühendis olarak çalışan Shigeo Shingo tarafından ortaya atılanPoka-Yoke fikri, insana bağlı hatanın ortadan kaldırılması anlamına gelmektedir. Poka kelime anlamı olarak;dikkatsizlik, dalgınlık, istenmeyen h...

  6. Tarihsel süreç içinde peyzaj tasarım ve uygulama çalışmalarında yapı malzemelerinin kullanımının irdelenmesi

    OpenAIRE

    Shakouri, Nasim

    2010-01-01

    Peyzaj, sayısız materyallerden oluşan görsel bir bütünlük olarak tanımlanmaktadır. Bu materyaller zaman içindeki değişimlerle, peyzaj tipi ve karakterini belirlemektedir. Peyzaj mimarlığında kullanılan materyaller, canlı ve cansız materyaller olarak ayrıca tanımlanmaktadır. Cansız materyaller kavramı içinde, peyzaj mimarlığında kullanılan yapısal öğelerin oluşturmasında önemli rol oynayan yapı malzemeleri de yer almaktadır. Peyzaj mimarlığında kullanılan yapısal malzemelerin özellikl...

  7. Süpermarket sektöründeki mobil pazarlama uygulamalarının tüketici davranışlarına etkisi: Aydın örneği

    OpenAIRE

    Eru, Oya

    2013-01-01

    Gelişen teknolojik koşullar iletişim teknolojilerinde de bir takım yeniliklerin yaşanmasını sağlamıştır. Günümüzde mobil teknolojiler ve mobil iletişim insanlar için vazgeçilmez hale gelmiştir. Özellikle İnternet-mobil cihaz birlikteliği, mobil teknolojilerin daha da gelişmesini ve sadece iletişim odaklılıktan çıkarak farklı boyutlarda kullanılmaya başlamasına neden olmuştur. Mobil cihazların her zaman kullanıcıları ile bir arada olduğu ve kimi tüketicilerin birden fazla mobil araca sahip ...

  8. Sapiens: Hayvanlar insanar

    OpenAIRE

    Yalı, Sibel

    2018-01-01

    Bu yazıda sizlere satış rekorları kıran bir tarihkitabından bahsetmek istiyorum. Kitap, 2011'de ibranice, 2014'te ingilizceyayımlandı ve şimdiye dek otuz civarında dile çevrildi. “Sapiens: İnsan Türünün Kısa Bir Tarihi” başlığı ile dilimizeçevrilen kitapta insanlık tarihinin serüvenine 70 bin yıllık zaman sürecindenbakılmaya çalışılıyor. Öyle bir kitap ki Amerika Başkanı Obama halkına bukitabı okumasını tavsiye ediyor. Öyle etkili bir kitap ki Facebook’un kurucusuMark Zuckerberg sos...

  9. Studi Pendahuluan Perubahan Garis Pantai Selama Zaman Kuarter di Daerah Kroya sampai Binangun Kabupaten Cilacap-Jawa Tengah

    Directory of Open Access Journals (Sweden)

    Asmoro Widagdo

    2013-06-01

    Full Text Available Cilacap coast line is a part of southern coast of Java at Cilacap Regency, Central Java. Topographic and satellite image observation shown some ancient coast lines behind the modern coast lines. How many of the coast lines which have formed before the modern coast lines is the question to be answered. This research is the preliminary effort to determine the direction of coast line development and the amount of coast lines which have formed before the modern ones. This preliminary research of the ancient coast lines is done by two stages of work that are studio and field work. Studio work was done by observation and interpretation of topographic map, land use map, Google Earth image and SRTM image. At this stage of work was made an ancient coast lineaments map and geomorphic profiles of the research area. To the results of the interpretation which have been done then taken a field work verification by ground check. Interpretation to the coast lines of the research area has resulted 24 coast lines. Ancient coast lines lineament of the research area is in line with the modern ones which have east-west lineament and prograde from the north to southward.

  10. Türkiye’de Tarih Öğretimi Hakkında Yayımlanmış Makaleler: Bir Bibliyografya Denemesi The Articles Published About History Teaching in Turkey: An Essay of Bibliography

    Directory of Open Access Journals (Sweden)

    Adem AYDEMİR

    2012-12-01

    Full Text Available There is a direct correlation between the acquisition of educational and instructional success and the applied methods and techniques in order to achieve this success. The studies with the process of informing the students in education area has always been changing and developing. People’s comprehending what they read and commenting on the subject are always intended and preferred processes in education area. It is exclaimed that literature review is one of the most importantsteps after the determination of topic for a research in researchmethods. It is an inevitable must that researchers determine theprevious research on the topics they are studying and discuss inparallel with their own studies. Today, it is seen that these studies, ofwhich importance increases, not only prevent the waste of time andwork in scientific studies but also make statistical studies easier.Historical consciousness is one of the most important objectivesattempted to be acquired through history teaching to students withincontemporary education systems. However, the studies with the processof informing the students in education area has always been changingand developing. A bibliography is very important for the researcherswho studies about the history teaching. In this bibliographic study,works on history teaching are dealt with the idea to contribute to theresearchers.This study is a bibliography essay of 280 articles, published inTurkey about history teaching. Articles are arranged according tosurname of writers in the bibliography. Eğitim ve öğretimde başarı, öğrenciyi belirlenen hedeflere ulaştırmak için takip edilen yöntem ve tekniklerle doğru orantılıdır. Eğitim alanında öğrencilere bilgi edindirme süreci ile ilgili çalışmalar her zaman değişme ve gelişme göstermektedir. İnsanların okuduğunu anlaması ve yorumlayabilmesi eğitim sürecinde her zaman istenilen ve tercih edilen bir süreçtir.Araştırma yöntemlerinde; yapılacak bir

  11. Choice of boundary condition for lattice-Boltzmann simulation of moderate-Reynolds-number flow in complex domains.

    Science.gov (United States)

    Nash, Rupert W; Carver, Hywel B; Bernabeu, Miguel O; Hetherington, James; Groen, Derek; Krüger, Timm; Coveney, Peter V

    2014-02-01

    Modeling blood flow in larger vessels using lattice-Boltzmann methods comes with a challenging set of constraints: a complex geometry with walls and inlets and outlets at arbitrary orientations with respect to the lattice, intermediate Reynolds (Re) number, and unsteady flow. Simple bounce-back is one of the most commonly used, simplest, and most computationally efficient boundary conditions, but many others have been proposed. We implement three other methods applicable to complex geometries [Guo, Zheng, and Shi, Phys. Fluids 14, 2007 (2002); Bouzidi, Firdaouss, and Lallemand, Phys. Fluids 13, 3452 (2001); Junk and Yang, Phys. Rev. E 72, 066701 (2005)] in our open-source application hemelb. We use these to simulate Poiseuille and Womersley flows in a cylindrical pipe with an arbitrary orientation at physiologically relevant Re number (1-300) and Womersley (4-12) numbers and steady flow in a curved pipe at relevant Dean number (100-200) and compare the accuracy to analytical solutions. We find that both the Bouzidi-Firdaouss-Lallemand (BFL) and Guo-Zheng-Shi (GZS) methods give second-order convergence in space while simple bounce-back degrades to first order. The BFL method appears to perform better than GZS in unsteady flows and is significantly less computationally expensive. The Junk-Yang method shows poor stability at larger Re number and so cannot be recommended here. The choice of collision operator (lattice Bhatnagar-Gross-Krook vs multiple relaxation time) and velocity set (D3Q15 vs D3Q19 vs D3Q27) does not significantly affect the accuracy in the problems studied.

  12. Restaurante "iFood-just eat it"

    OpenAIRE

    Silva, Francisco Carlos Duarte da

    2012-01-01

    Mestrado em Gestão Vivemos num mundo super volátil, incerto, ambíguo e complexo. Rapidez e velocidade são tudo nos dias de hoje. Nas empresas há que criar movimento, inspirar as pessoas, mudar do pensamento racional para o emocional, de forma a provocar acção e criar fórmulas de sucesso. O intento deste trabalho é desenvolver um plano de negócios inovador para um restaurante. O conceito de restaurante inovador consiste em proporcionar a cada um dos seus clientes, um itinerário individua...

  13. Uma lógica para a referência ambígua

    OpenAIRE

    Sebben, Andressa

    2007-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Ciência da Computação. Descritores são operadores que formam termos a partir de variáveis e fórmulas de sistemas lógicos. Diversas teorias introduzem descritores para representar, em linguagens formais, o artigo definido (o/a) e o artigo indefinido (um/uma) das linguagens naturais. Entretanto, as abordagens mais conhecidas não oferecem um tratamento para termos ambíguos. A lógi...

  14. O herói-trapaceiro. Reflexões sobre a figura do trickster*

    Directory of Open Access Journals (Sweden)

    Renato da Silva Queiroz

    1991-12-01

    Full Text Available A figura do herói-trickster tem sido investigada pelos antropólogos e pelos estudiosos da mitologia universal. Personagem polêmico por natureza, ambíguo e contraditório, o trickster vem sendo encontrado tanto nos relatos míticos das sociedades indígenas quanto na produção literária e folclórica e das formações sociais complexas. Desta forma, o trickster constitui uma categoria bastante ampla, e os problemas interpretativos daí decorrentes espicaçam a curiosidade dos antropólogos.

  15. A descriptive study on the manifestations of lexical ambiguity in LIBRAS.

    OpenAIRE

    TÃnia Aparecida Martins

    2013-01-01

    Esta dissertaÃÃo objetiva realizar um estudo descritivo acerca da ambiguidade lexical na LÃngua Brasileira de Sinais â Libras â por meio de investigaÃÃes na literatura especializada, culminando com a construÃÃo de um corpus com itens lexicais ambÃguos lematizados, respectivamente em dois dicionÃrios bilÃngues: O dicionÃrio da LÃngua Brasileira de Sinais/LIBRAS versÃo 2.0, 2008 (digital) e o DicionÃrio EnciclopÃdico Ilustrado TrilÃngue Novo Deit-Libras (2012). Para os estudos gerais sobre o as...

  16. Immunohistochemical expression of nitric oxide synthases in gastric adenocarcinomas

    OpenAIRE

    Begnami, Maria Dirlei F. S.; Cunha, Isabela Werneck da; Montagnini, André; Nonogaki, Sueli; Soares, Fernando

    2004-01-01

    INTRODUÇÃO: O óxido nítrico (NO) é uma molécula mediadora de diversas funções, tais como vasodilatação, neurotransmissão e metabolismo do ferro. Os efeitos do NO na biologia tumoral são ambíguos e complexos. A atividade das sintases do óxido nítrico (NOS) tem sido demonstrada em diversos tumores humanos. OBJETIVO: Pesquisar a expressão das isoformas das NOS em carcinomas gástricos e correlacionar estes achados com características demográficas e histopatológicas destes tumores. MATERIAL E MÉTO...

  17. Análise imuno-histoquímica das sintases do óxido nítrico em adenocarcinomas gástricos

    OpenAIRE

    Begnami,Maria Dirlei F. S.; Cunha,Isabela Werneck da; Montagnini,André; Nonogaki,Sueli; Soares,Fernando

    2004-01-01

    INTRODUÇÃO: O óxido nítrico (NO) é uma molécula mediadora de diversas funções, tais como vasodilatação, neurotransmissão e metabolismo do ferro. Os efeitos do NO na biologia tumoral são ambíguos e complexos. A atividade das sintases do óxido nítrico (NOS) tem sido demonstrada em diversos tumores humanos. OBJETIVO: Pesquisar a expressão das isoformas das NOS em carcinomas gástricos e correlacionar estes achados com características demográficas e histopatológicas destes tumores. MATERIAL E MÉTO...

  18. Attack strategies on quantum cryptographic protocols

    International Nuclear Information System (INIS)

    Schauer, S.; Suda, M.

    2006-01-01

    Full text: Quantum key distribution (QKD) and quantum authentication (QA) have been a topic of extensive research in the last 20 years. In course of that many attacks on QKD and QA protocols have been studied. Among these, Zhang, Lee and Guo presented an attack on a QKD protocol using entanglement swapping. Based on that strategy we take a look at other protocols to inspect how much information an adversary may get if he shares entanglement with either one or both parties. We will present some protocols where an adversary can even get full information about the key using entanglement. (author)

  19. PEMBARUAN PENDIDIKAN ISLAM AZYUMARDI AZRA: Melacak Latar Belakang Argumentasinya

    Directory of Open Access Journals (Sweden)

    Hastuti Baharuddin

    2013-12-01

    Full Text Available Abstrak: Pembaruan adalah proses atau cara membarui yang menghasilkan perubahan da-lam penyesuaian situasi dan kondisi. Pendidikan Islam adalah proses mempersi-apkan generasi muda (pembentukan individu untuk menjalankan kehidupan (sebagai khalifah dan untuk memenuhi tujuan hidup secara efektif dan efisien berdasarkan sumber-sumber Islam berupa al-Qura’n, sunnah, dan ijtihad. Pemba-ruan pendidikan Islam merupakan tuntutan kebutuhan dunia pendidikan Islam saat ini. Melihat ketertinggalan dan keterbelakangan umat Islam dewasa ini, maka inti dari pembaruan pendidikan Islam adalah berupaya meninggalkan pola pikir lama yang tidak sesuai dengan kemajuan zaman (future oriented dan berupa meraih aspek-aspek yang menopang untuk menyesuaikan diri dengan kema-juan zaman. Pendidikan Islam yang sebenarnya adalah balanced between worldly life and hereafter (keseimbangan antara dunia dan akhirat, balanced between revealed knowledge and acquired knowledge (keseimbangan antara pengetahuan wahyu dan pengetahuan usaha manusia, balanced between iman-taqwa and science and technology (keseimbangan antara imtak dan iptek sehingga menghasilkan kesejahteraan spiritual dan material. Abstract: Renewal is a process or a way of renewing the adjustment results in a change in circumstances. Islamic education is the process of preparing the younger genera-tion (generation people to run life (as Caliph and to meet life goals effectively and efficiently based on the Islamic sources, the Qur'an, the sunnah, and ijtihad. Renewal of Islamic education is a demand to the needs of Islamic education in this time. Seeing underdevelopment and backwardness of Muslims today is that the core of the reform of Islamic education is attempting to leave the old mindset that is not in accordance with the progress of time (future oriented and strive for sustaining aspects to conform with the progress of time. Islamic education is actually is balanced between worldly life and hereafter, balanced

  20. Tradisi Ziarah Makam Bathara Katong (Tinjauan Deskripsi Akulturasi Budaya

    Directory of Open Access Journals (Sweden)

    Amirul Nur Wahid

    2018-05-01

    Full Text Available Masyarakat Jawa, tak terkecuali masyarakat Ponorogo seringkali memiliki kebiasaan-kebiasaan tertentu yang dilakukakan. Kebiasaan-kebiasaan ini diwariskan secara turun temurun hingga menjadi sebuah tradisi. Tradisi ziarah makam Bathara Katong merupakan salah satunya. Tradisi ini dilakukan oleh masyarakat Ponorogo dan sekitarnya sejak zaman dahulu. Bathara Katong merupakan tokoh sentral dalam penyebaran agama Islam. Pada saat itu terjadi transisi antara agama lama dan baru dari segala aspek. Transisi inilah yang menjadikan akulturasi budaya diantara kedua hal tersebut. Akulturasi budaya ini juga merambah bidang kesenian di area sekitar makam, misalnya munculnya kesenian Jemblung yang merupakan akulturasi antara dua kebudayaan menjadi satu. Selain kesenian, akulturasi juga dapat ditemukan di arsitektur bangunan-bangunan, proses ziarah, serta benda-benda yang dibawa oleh peziarah makam Bathara Katong. Nama Bathara Katong sendiri sebenarnya merupakan sebuah akulturasi kebudayaan. Hanya saja dikarenakan mengikuti perkembangan zaman, tradisi ini juga mengalami perubahan-perubahan dalam akulturasinya. Artikel ini akan mencoba mengupas hal tersebut. Javanese are no exception Ponorogo people have certain habits. This habit is passed down from generation to generation and then becomes a tradition. The pilgrimage tradition of Bathara Katong's tomb is one of them. This tradition is done by the people of Ponorogo and its surroundings since antiquity. Bathara Katong is a central figure in the spread of Islam in Ponorogo. There was a transition between old and new cultures from various aspects. This transition is considered to be the cause of cultural acculturation. Acculturation of this culture also penetrated the field of art in the area around the tomb, for example the emergence of art Jemblung which is the acculturation between two cultures into one. In addition to art, acculturation can also be found in the architecture of the building, the process of

  1. Türk İstihbaratının Tarihsel Gelişimi

    Directory of Open Access Journals (Sweden)

    Eray GÖÇ

    2013-09-01

    Full Text Available Bu çalışmanın amacı, Türk istihbaratının Osmanlı’nın özellikle son dönemlerinden günümüze tarihsel gelişimi hakkında bilgi vermektir. Tarih sahnesinde istihbarat örgütlerinin üstlendikleri rolleri Türk siyasi hayatına etkilerini araştırmış, günümüz toplum yapısının oluşmasında üstlendikleri roller hakkında bilgi vermiştir. Çalışma Osmanlıda hafiye teşkilatı ile başlayıp, İttihat ve Terakki, MAH, JİTEM, ÖHD ve MİT ile devam eden bir silsilenin Anadolu toprakları üzerinden 100 yılı devirmiş etkisine dair bilgiler içermektedir. Kitap, dergi, makale gibi kaynakların yanı sıra konuyla ilgili çeşitli çalışmalar yapmış olan susurluk araştırma komisyonu başkanı Mehmet Elkatmış, AK parti milletvekili Şamil Tayyar ve gazeteci Nasuhi Güngör ile konuyla ilgili yapılan röportaj da çalışmada yer almaktadır. Çalışma bir taraftan da istihbarat örgütlerinin, devlete hukuk çizgisinin dışına çıkma manevrası kazandırdığı sorunsalını irdelemektedir. Devlet, istihbarat örgütleri sayesinde bekası adına hukuk dışılığı ilke edinme gayretine girmiş olabilir mi? Ya da istihbarat örgütleri devlet adına deyip zaman zaman gayri nizami davranışlar sergilemiş midir? Bu sorular irdelenmiştir.

  2. An oxygen isotope study of quartz veins within eclogites from the Dabie terrane

    Institute of Scientific and Technical Information of China (English)

    LI; Yiliang

    2001-01-01

    ［1］Liu, T. S., Loess and the Environment, Beijing: China Ocean Press, 1985, 1-251.［2］Chen, L. X., Zhu, Q. G., Luo, H. B. et al., East Asian Monsoon, Beijing: China Meteorology Press, 1991, 28-61.［3］An, Z. S., Liu, T. S., Lu, Y. C. et al., The long-term palaeomonsoon variation recorded by the loess-palaeosol sequence in central China, Quaternary International, 1990, (7/8): 91-95.［4］Guo, Z. T., Liu, T. S., Fedoroff, N. et al., Shift of the monsoon intensity on the Loess Plateau at ca. 0.85 MaBP, Chinese Science Bulletin, 1993, 38(2): 586-591.［5］Chen, J., An, Z. S., Wang, Y. J. et al., Distributions of Rb and Sr in the Luochuan loess-paleosol sequence of China during the last 800 ka: Implications for paleomonsoon variations, Science in China, Ser. D, 1999, 42(3): 225-232.［6］Chen, J., Wang, Y. J., Ji, J. F. et al., Rb/Sr variations and its climatic stratigraphical significance of a loess-paleosol profile from Luochuan, Shaanxi Province, Quaternary Sciences (in Chinese), 1999, 19(4): 350-356.［7］Guo, Z. T.,Liu, T. S., Fedoroff, N. et al., Climate extremes in loess of China coupled with the strength of deep-water for-mation in the North Atlantic, Global and Planetary Change, 1998, 18: 113-128.［8］Guo, Z. T., Liu, T. S., An, Z. S., Paleosols of the last 0.15 Ma in the Weinan loess section and their paleoclimate signifi-cance, Quaternary Sciences (in Chinese), 1994, 14(3): 256-269.［9］Guo, Z, T,, Fedoroff, N., Liu, T. S., Micromorphology of the loess-paleosol sequence of the last 130 ka in China and pa-leoclimatic event, Science in China (in Chinese), Ser. D, 1996, 26(3): 392-398.［10］Guo, Z., Liu, T., Guiot, J., et al., High frequency pulses of East Asian monsoon climate in the last two glaciations: Link with the North Atlantic, Climate Dynamics, 1996, 12: 701-709.［11］Guo, Z. T., Peng, S. Z., Wei, L. Y. et al., Weathering signals of Millennial-Scale oscillations of the East Asian Summer monsoon over the last 220 ka, Chinese Science

  3. Müşteri İlişkileri ve CRM = Customer Care & Social CRM

    OpenAIRE

    Yaşar, Azra Betül

    2016-01-01

    Azra Betül Yaşar şu anda Turkcell'de çalışmaktadır ve müşteri ilişkileri yönetimi alanında uzman olarak hizmet vermektedir. Mart 2011'den beri bu görevi yürüten Yaşar; proje yönetimi, stratejik planlama, bilgi yönetimi, sosyal medya, bütçe yönetimi, ve data analizi konularında deneyim kazanmış birisidir. Müşterilerin Turkcell ile en iyi şekilde iletişimde kalmasını sağlamak, ve Turkcell deneyimlerini her zaman en yukarda tutmak için çalışmaktadır. Doğu Akdeniz Üniversitesi (DAÜ) Sosyal Med...

  4. Berlin Olimpiyatları ekseninde basında Türk sporu (1936-1938)

    OpenAIRE

    GÜNGÖR, Birgül

    2009-01-01

    Olimpiyatlar her zaman kavga ve düşmanlıkların bir kenara bırakıldığı, barış, kardeşlik, dostluk duygularının ön plana çıktığı dünyanın en büyük spor organizasyonu olarak anılır. Antik çağda ilk kez Yunanistan'da gelenekselleşen Olimpiyatlar, daha sonra modern çağa ayak uydurularak her dört yılda bir, bu büyük spor şölenini organize edebilme gücüne sahip büyük...

  5. Sanat Yapıtı Sergileme ve Sunum Çeşitlerine Örnekler Eşliğinde Bir Bakış

    OpenAIRE

    AYAN ERGEN, Burcu

    2014-01-01

    Sergi, sahip olunanları gerek göstermek gerekse ticaret amacıyla başkalarına sunmak için oluşturulan bir düzendir. Sergilemek eski kullanımıyla teşhir etmek anlamına gelir. Sergileme ve sunum yöntemleri, gereksinimlerin ve teknolojinin zaman içinde geçirdiği evrime bağlı olarak sürekli değişen ve yenilenen bir biçim alır. Günümüzde müze ve galerilerde sergileme çeşitleri üzerinde durulacak ve sergilerin oluşturulma düşüncesi ile nasıl oluşturulduğunun inceleneceği bu bildiride, örnekler üzeri...

  6. An analysis of teacher news in Turkish printed media within the context of teachers’ image

    Directory of Open Access Journals (Sweden)

    Hüseyin Polat

    2016-12-01

    Full Text Available The purpose of this study was to analyze the news about teachers in daily newspapers circulated in Turkey. To this end, the newspapers of Zaman, Posta, Hurriyet, Sabah, and Cumhuriyet were selected and scanned for the teacher news between the dates of 01 January 2014 and 31 December 2014. Document analysis technique was used for the scanned news. The data obtained were expressed in frequencies and percentages according to the aim. News about the teachers was grouped on the basis of type, content, and characteristics and the teacher profile presented from this data was set forth. Teachers are mainly covered in the newspapers in sexual abuse and violence contexts; besides, the teacher profile formed on the basis of newspaper reports was found to be a negative one.

  7. A Meeting : The Relation between Religion, Science, and Philosophy : The Perspective of the Risale-i Nur

    OpenAIRE

    Altıntaş, İhsan

    2012-01-01

    üzere Prof. Dr. Yunus Çengel Fen-Felsefe-İnanç Üçgeninde Risale-i Nur konulu açılış tebliğini sundu. Tebliğinde, öncelikle terimler arasındaki kargaşanın gide- rilmesi gerektiği vurgusunu yaparak zaman kavramının da artık bireyselleştiğini belirtti. Çengel konuşmasında şu sözlere yer verdi: “fen-felsefe ve inanç birbirini etkiler, Said Nursi inanç meselelerini mantık ve muhakeme bakış açısıyla değer- lendirir. Felsefeyi reddetmez. Fen, felsefe ve inanç meselelerini Risale-i Nur bakış açıs...

  8. Emeviler Döneminde Para / Money in Dynasyt of Emevies

    OpenAIRE

    Emanet, Celal

    2014-01-01

    Özet Arap yarımadasında İslamiyet'in doğuşu ve gelişmesi sırasında ve daha sonraki fetihlerin yer aldığı ilk yarım yüzyılda Araplar ele geçirdikleri ülkelerde kullanılan para ve ölçü birimlerini değiştirmediler. İslam öncesi dönemde kullanılan paralar Hz. Peygamber ve ilk dört halife zamanında da aynen kullanılmaya devam etti. Kullanılan bu paralar arasında Rumî adı verilen Bizans altınları, Kisrevî adı verilen Sasanî dirhemleri ve Yemen'den gelen Himyeriye'ler bulunmaktadır. H...

  9. Fen Bilgisi Öğretmen Adaylarının Kimya Bilgilerini Günlük Hayatla İlişkilendirebilme Düzeyleri

    OpenAIRE

    Yadigaroğlu, Yrd. Doç. Dr. Mustafa; DEMİRCİOĞLU, Doç. Dr. Gökhan; DEMİRCİOĞLU, Doç. Dr. Hülya

    2017-01-01

    Fen eğitiminin temel amaçlarındanbiri, öğrencilerin fen okur-yazarı olmalarını sağlayarak onları günlükyaşantılarında karşılaştıkları fen olaylarına anlam vermelerine yardımcıolmaktır. Günlük hayatla ya da bağlamı ile ilişkilendirilmeyen bilgi öğrencininzihninde her zaman eksik olacaktır. Bunun gerçekleştirilmesinde fen dersleriiçerisinde yer alan kimya önemli bir yere sahiptir. Bu düşünceden hareketleçalışmada, fen bilgisi öğretmen adaylarının kimya bilgilerini günlük hayatlailişkilendirebil...

  10. HİZMET İŞLETMELERİNDE ÇAĞRI MERKEZİ VE BEKLEME HATTI UYGULAMALARINA TÜKETİCİ ODAKLI BİR YAKLAŞIM

    OpenAIRE

    ÇİÇEK, Ercan; ATILGAN, Kalender Özcan

    2012-01-01

    Dünyada ve Türkiye’de hizmet sektörünün gelişimi hızla sürmekte ve işletmeler, tüketici beklentilerinin artması ve yaşanan yoğun rekabet sonucu hizmet düzeyini, etkinliğini ve sürekliliğini arttırma ihtiyacını duymaktadırlar. Bu bağlamda, hizmet yöneticisine önemli görevler düşmektedir. Çoğu hizmet işletmesinde, bekleme konusu, tüketicilerin hizmeti değerlendirmesinde odak unsur olmaktadır. Tüketici bakış açısından değerlendirildiğinde beklemenin en olumsuz sonucu zaman kaybıdır. Bekleme zama...

  11. GELİŞEN TURİZM DESTİNASYONLARINDAN BİRİ OLARAK AKSARAY İLİNİN ALTERNATİF TURİZM POTANSİYELİNİN BELİRLENMESİNE YÖNELİK BİR ARAŞTIRMA

    OpenAIRE

    TUNCER, Mehmet; ÇAVUŞ, Selahattin

    2017-01-01

    Değişentoplumsal ve siyasi dinamikler ile teknoloji alanındaki ilerleme, turizmde deetkisini göstermektedir. İnsanların dinlenme, eğlenme ve seyahat ile ilgiliistek ve ihtiyaçlarının zaman içerisinde değişmesi yeni turizm tip veşekillerinin oluşmasını sağlamaktadır. Böylelikle, bilinen turizm hareketleriyanında tarihi, kültürel ve çevresel öğelerin ön planda olduğu turizmçeşitlerinin giderek önem kazandığı görülmektedir. Bu doğrultuda Türkiye’de veDünyada çeşitli çalışmalar incelenmiş ve lite...

  12. Yeni Bir Felsefe Işığında Yan Sanayilerden Beklenenler ve Tam Zamanında Üretim

    Directory of Open Access Journals (Sweden)

    Ali Rıza FİRUZAN

    2004-01-01

    Full Text Available Today, one of the most important sector in an economy is the production sector, the importance of goods and services sectors are increasing at a fastly every day. Until today, competitive conditions, efficiency, productivity and quality of production, forced to the firms to put more emphasis on production systems. Therefore, the firms are more interested in scientific analysis, planning and controllingof the their production systems. As a result, one of the newest approaches is ‘Just in Time (JIT’ production system which emerged after WWII in Japan and aims to decrease the inventory cost and maximize the quality. The philosophy of this approach is to produce the necessary amount of production, when and where needed at the required quality. The aims of JIT is to improve the product and the process continously. The aim of this study is to investigate JIT as a new approach for Turkey in all aspects and analyze its applicability for firms.

  13. Concept and theory of clustered-cavity gyroklystrons

    International Nuclear Information System (INIS)

    Nusinovich, G.S.; Guo, H.; Antonsen, T.M. Jr.; Granatstein, V.L.

    2002-01-01

    The concept of clustered cavities was originally proposed by R. Symons for use in linear-beam klystrons operating in TM-modes. It was proven experimentally that the use of this concept allows developers to double the instantaneous bandwidth of klystrons without changing their overall dimensions or sacrificing gain and bandwidth. Recently, H. Guo suggested applying this concept to gyroklystrons operating in TE-modes. In the present paper this concept is formulated and a simple analytical theory describing qualitatively the performance of clustered-cavity gyroklystrons is developed. Results of the analysis of a simple two-stage gyroklystron indicate that the clustered-cavity concept has potential for improving the performance of gyroklystrons

  14. Prof.Dr. Ahmed Yüksel Özemre’nin Tasavvufî Görüşleri

    OpenAIRE

    KALKAN, Bilgihan

    2015-01-01

    Prof. Dr. Ahmed Yüksel Özemre(1935-2008), Türkiye’nin ilk atom mühendisiolmasının yanı sıra Türkiye Atom Enerjisi (TAE) Kurumundaki görevidolayısı ile ülkemizin tanınmış ilim adamlarındandır. Bu makalede Prof. Dr. AhmedYüksel Özemre’nin daha az bilinen ve çocukluk çağlarında tasavvufî muhitlerile yakın temas halinde bulunması ile başlayan ve zaman içerisinde yalnızcaentelektüel bir uğraş olmanın ötesine geçerek, yaşam şekline dönüşen tasavvufîhayatı ve genel hatları ile İslâm tasavvufu hakkın...

  15. LİNYİT KÖMÜRLERİNDEN ELDE EDİLEN AKTİF KÖMÜR İLE SULU ÇÖZELTİLERDEN Cr(VI UZAKLAŞTIRILMASI

    Directory of Open Access Journals (Sweden)

    Mehmet MAHRAMANLIOĞLU

    2001-03-01

    Full Text Available Ağaçlı Linyit kömürlerinden elde edilen aktif kömür, sulu çözeltilerden Cr(VI uzaklaştırmak için kullanılmıştır. Cr(VI adsorpsiyonu başlangıç konsantrasyonu, zaman, pH, adsorbent konsantrasyonu ve sıcaklığın fonksiyonu olarak çalışılmıştır. Adsorpsiyon verileri Langmuir ve Freundlich izotermlerine uydurulmuştur. Adsorpsiyon hız sabitini hesaplamak için Lagergren eşitliği kullanıldı. Adsorbe edilen Cr(VI miktarı pH değerinin azalması ile artmış, sıcaklığın artması ile azalmıştır.

  16. Epistemologi Anarkisme Paul Feyerabend dalam Studi Ilmu Tafsir al-Quran

    Directory of Open Access Journals (Sweden)

    Kurdi Fadal

    2015-03-01

    Full Text Available Tulisan ini mengkaji tentang epistemologi anarkisme Paul Feyerabend dalam studi tafsir al-Qur'an. Selama ini studi tafsir al-Qur'an telah berkembang sangat pesat sejak periode formatif, afirmatif hingga transformatif. Berbagai metode dan pendekatan telah lahir mengiringi. Perkembangan itu menunjukkan bahwa studi tafsir berjalan secara dinamis. Namun, sebagian menilai tafsir al-Qur'an telah selesai pasca generasi ketiga dalam Islam. Melalui prinsip Anything Goes yang digagas Feyerabend, metode dan pendekatan apapun yang ditawarkan untuk menafsirkan al-Qur'an dapat berjalan dan "berkontestasi" secara terbuka. Satu sisi, hal ini sangat positif bagi perkembangan ilmu tafsir dalam konteks kemajuan zaman. Namun di sisi lain, anarkisme dalam bidang ini dapat menimbulkan tafsir liar yang melahirkan problem bagi kemajuan peradaban, seperti lahirnya terorisme dalam Islam yang sering disandarkan pada ayat-ayat al-Qur'an sebagai sumber justifikasinya.

  17. Komunisme Sebuah Utopia dalam Era Globalisasi: Tinjauan Historis terhadap Pemikiran Karl Marx

    Directory of Open Access Journals (Sweden)

    Nasrullah Nazsir

    2001-12-01

    Full Text Available Kehancuran negara-negara berhaluan komunis pasca Perang Dingin menyebabkan keabsahan ideologi komunis yang digagas Marx dipertanyakan kembali. Kendati demikian, hancurnya pemerintahan negara-negara komunis tersebut tidak berarti matinya komunisme. Banyak pemikiran baru muncul mereinterpretasi gagasan Marx berlandaskan pada kritik dan otokritik yang dilakukan sejumlah Marxis, mulai dari Friedrich Engels yang hidup sezaman dengan Marx, hingga Marxis-Marxis sesudahnya seperti Herbert Marcuse, Roger Garaudy, Jurgen Habermas dan T.W. Adorno. Disimpulkan, Marxisme sebagai sebuah gerakan pemikiran tidak akan pernah mati, karena akan selalu diinterpretasi untuk menjawab tantangan zaman dewasa ini, yang masih ditandai oleh saratnya permasalahan manusia, alienasi, ketimpangan, ketidakadilan, dan berbagai penyakit masyarakat lainnya. Dalam konteks masa kini, paham Marxis bertransformasi menjadi multimuka Marxisme yang menawarkan gagasan-gagasan segar, sekaligus kontroversial seperti Gerakan New Left dan usulan kerjasama antara kaum agamis dan komunis dalam Teologi Pembebasan Amerika Latin.

  18. Sosyal medyada reklam kullanımı örneği olarak yerli reklamların incelenmesi

    OpenAIRE

    Ergin, Ertan Eren

    2015-01-01

    Hızla gelişen iletişim çağı ile insanoğlunun istekleri ve ihtiyaçları önemli düzeyde artmıştır. Sosyal medya çağına gelene kadar bütün iletişim, reklam ve bilgilendirme ve duyurular geleneksel medya kanalları üzerinden yapılmaktaydı. Geleneksel medya yayınlarında iletişim tek yönlü bir yapıya sahipti ve kullanıcıya ulaşan bilgi zaman ve mekan yönünden farklılık göstermekteydi. Fakat sosyal medya ile birlikte kullanıcılar dinleyici konumundan çıkıp, etkileşim içine girerek daha aktif bir rol a...

  19. S-02: Venöz Yetmezlikli Hastalarda Kalf Kası Egzersizlerinin Venöz Fonksiyona ve Kas Kuvvetine Etkisi

    Directory of Open Access Journals (Sweden)

    Sabriye Ercan

    2017-03-01

    Full Text Available Kronik venöz yetmezlik, alt ekstremitenin ilerleyici hipertansiyonu sebebiyle kalf kaslarında zayıflık ile giden bir hastalıktır. Erken tanı ve etkili konservatif tedaviler ile hastalığın ilerleyişi önlenebilir. Venöz geri dönüşü arttırmak ve kalf kas pompasını restore etmek için hastalara egzersiz önerilmektedir.Bu çalışmanın amacı; kronik venöz yetmezlikli hastalarda, iki farklı kalf egzersizi programının ayak bileği eklem hareket açıklığına, kuvvete, ağrıya, yaşam kalitesine ve venöz geri dolum zamanına etkisini analiz etmekti.Çalışmaya, kronik venöz yetmezlik tanılı 71 hasta alındı ve hastalar rasgele iki gruba ayrıldı. Ayak bileği eklem hareket açıklığı ölçümünde gonyometre, kas kuvveti ölçümünde izokinetik dinamometre kullanıldı. Venöz geri dolum zamanı, fotopletismografi kullanılarak ölçüldü. Vizüel Analog Skala değeri ağrı seviyesini, EQ-5D genel yaşam kalite ölçeği yaşam kalitesinin seviyesini tanımlamak için uygulandı. 12 hafta boyunca (3 seans/hafta Grup 1’deki hastalar ev tabanı kalf egzersizlerini, Grup 2’deki hastalar ise aynı egzersizleri ve izokinetik kalf kası egzersizlerini yaptı. Çalışmanın sonunda 42 hastanın kontrol verileri alındı. Kontrol değerleri karşılaştırıldığında gruplar arasında ağrı seviyesi ve kas kuvveti parametrelerinden ayak bileği plantarfleksiyon-dorsifleksiyon pik tork oranı ve toplam iş parametreleri açısından istatistiksel anlamlı fark tespit edildi (p<0,05. Başlangıç değerleri ile karşılaştırıldığında ise Grup 2’nin tüm ölçümlerinde, Grup 1’in ayak bileği dorsifleksör pik tork, pik tork/vücut ağırlığı ve venöz geri dolum zamanında istatistiksel anlamlı fark tespit edildi (p<0,05.Kronik venöz yetmezliği olan hastalarda egzersizin venöz fonksiyonu düzenlemedeki etkisi çalışmamızla bir kez daha ortaya konmuş, izokinetik egzersizin etkisi ise literat

  20. Comparison of disposable sutureless silicone ring and traditional metal ring in 23-gauge vitrectomy combined with cataract surgery

    Directory of Open Access Journals (Sweden)

    Li X-R

    2011-06-01

    Full Text Available Jian-Guo Wu, Rui-Hua Wei, Ai-Hua Liu, Xiao-Xu Zhou, Guo-Ling Sun, Xiao-Rong LiTianjin Medical University Eye Center, Tianjin, ChinaBackground: The purpose of this prospective, interventional, comparative case series was to evaluate the efficiency and feasibility of a disposable sutureless silicone lens ring for corneal contact lens stabilization during combined 23-gauge vitrectomy and cataract surgery.Methods: We developed a ring consisting of a single silicone component with three footplates along the ring margin to fit cannulae for holding conventional contact lenses. Thirty eyes from 30 patients with cataract and vitreoretinal disease were included, and divided into two matched groups according to disease type and ring used. In Group A, we used a 23-gauge transconjunctival vitrectomy system and a disposable sutureless silicone lens ring (n = 15. In Group B, we used a 23-gauge transconjunctival vitrectomy system and a conventional metal lens ring (n = 15. The main outcome measures were: time required for vitrectomy preparation, rate of intraoperative corneal limbus bleeding, and limbus scar rate at the final follow-up visit.Results: Thirty cases were successfully completed. The average vitrectomy preparation time was less in Group A than in Group B (P < 0.01, and the average preparation time saved was 3.94 minutes. None of the Group A patients had intraoperative bleeding or postoperative scarring, whereas all 15 Group B cases had bleeding and five had scarring. There was a statistically significant difference between Group A and Group B for these complications (P ≤ 0.05.Conclusion: This report demonstrates the advantages of using a sutureless silicone ring during combined 23-gauge vitrectomy and cataract surgery. Using this method could allow extra time for the surgeon to pay more attention to complex vitreoretinal procedures.Keywords: pars plana vitrectomy, contact lens, silicone ring, cataract surgery

    1. Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung

      International Nuclear Information System (INIS)

      Izzotti, Alberto; Larghero, Patrizia; Longobardi, Mariagrazia; Cartiglia, Cristina; Camoirano, Anna; Steele, Vernon E.; De Flora, Silvio

      2011-01-01

      Our previous studies demonstrated that exposure to cigarette smoke (CS), either mainstream or environmental, results in a remarkable downregulation of microRNA expression in the lung of both mice and rats. The goals of the present study were to evaluate the dose responsiveness to CS and the persistence of microRNA alterations after smoking cessation. ICR (CD-1) neonatal mice were exposed whole-body to mainstream CS, at the doses of 119, 292, 438, and 631 mg/m 3 of total particulate matter. Exposure started within 12 h after birth and continued daily for 4 weeks. The levels of bulky DNA adducts and 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodGuo) were measured by 32 P postlabeling procedures, and the expression of 697 mouse microRNAs was analyzed by microarray. The highest CS dose was lethal. Exposure to CS caused a dose-dependent increase of DNA alterations. DNA adducts and, even more sharply, 8-oxodGuo were reverted 1 and 4 weeks after smoking cessation. Exposure to CS resulted in an evident dysregulation of microRNA expression profiles, mainly in the sense of downregulation. The two lowest doses were not particularly effective, while the highest nonlethal dose produced extensive microRNA alterations. The expression of most downregulated microRNAs, including among others 7 members of the let-7 family, was restored one week after smoking cessation. However, the recovery was incomplete for a limited array of microRNAs, including mir-34b, mir-345, mir-421, mir-450b, mir-466, and mir-469. Thus, it appears that microRNAs mainly behave as biomarkers of effect and that exposure to high-dose, lasting for an adequate period of time, is needed to trigger the CS-related carcinogenesis process in the experimental animal model used.

    2. Effects of discharge operation regimes and magnetic field geometry on the in-out divertor asymmetry in EAST

      International Nuclear Information System (INIS)

      Du, Hailong; Sang, Chaofeng; Wang, Liang; Bonnin, Xavier; Sun, Jizhong; Wang, Dezhen

      2016-01-01

      Highlights: • The in-out divertor asymmetry is studied using SOLPS. • The discharge operation and the magnetic filed have a great influence on the divertor asymmetry. • The asymmetry is not obvious in low recycling regime as that in high recycling regime. - Abstract: This paper aims to investigate the reason why the divertor in-out asymmetry was not obvious as experimentally observed in EAST only considering the classical drifts from previous simulations (Guo et al., J. Nucl. Mater. 438 (2013) 280; Du et al., J. Nucl. Mater. 463 (2015) 485). With consideration of the classical drifts, a series of different typical discharge scenarios in EAST in different magnetic field geometries were simulated by using the SOLPS5.2 code package. The simulated results reveal that the classical drifts make a major contribution to the in-out divertor asymmetry in the high recycling regime (HRR) and partial detachment (one divertor target begins to detach, while the other divertor remains attached) regime. In comparison, in low recycling regime the classical drifts play a much smaller role in the contributions to the in-out divertor asymmetry, which can explain reasonably the reason for it in Guo et al. (J. Nucl. Mater. 438 (2013) 280). In addition, the magnetic field geometry also has a great impact on the classical drifts inducing the asymmetry; it is found that for lower single-null, upper single-null and connected double-null topologies, in HRR the classical drifts play an dominant role in the contribution to the in-out divertor asymmetry, while for a disconnected double null magnetic field configuration, they play a minor role, which is the reason why the in-out asymmetry was unobvious by considering the drifts in Du et al. (J. Nucl. Mater. 463 (2015) 485).

    3. Analysis of Temporal and Spatial Distributions of Ammonia Nitrogen in the Huaihe River Basin from 1998 to 2014

      Science.gov (United States)

      Xu, J.; Jin, G.; Tang, H.; Li, L.

      2016-12-01

      To assess the effectiveness of water pollution control measures taken in the Huaihe River Basin (HRB) in China, we analyzed the temporal and spatial distributions of ammonia nitrogen (NH3-N) in the river water from 1998 to 2014 (three Chinese Five-year Plan periods).Analysis of measured NH3-N concentrations from various monitoring stations using the STL (seasonal trend decomposition using loess) method and a modified log-linear model revealed that: (1) The rate of NH3-N concentration reduction over the whole period was 70% 81% in the main stream of Huaihe River, but reached 88% in two major tributaries - the Shaying River and Guo River. (2) The NH3-N concentrations decreased significantly particularly between the tenth Five-year Plan and eleventh Five-year Plan periods in the main stream. In comparison, significant NH3-N reduction occurred over all three Five-year Plan periods in the Shaying and Guo tributaries. The concentration in the first year of a Five-year Plan period tended to much higher than that in the last year of the same period, likely due to the difference in implementing the pollution control measures. (3) The NH3-N concentrations were higher in the spring (fertilization period) and winter (low discharge) than in the summer and autumn. (4) With the implementation of pollution control measures, the contribution rate of NH3-N in the two major tributaries from point sources has decreased from 74% 93% in earlier years to 3% 28% in later years. However, NH3-N input from non-point sources appeared to remain stable and largely depend on runoff. To further reduce the NH3-N concentration in the river, policies and control measures should focus on non-point sources.

    4. Protective effect of 4-coumaric acid from UVB ray damage in the rabbit eye.

      Science.gov (United States)

      Lodovici, Maura; Caldini, Silvia; Morbidelli, Lucia; Akpan, Victor; Ziche, Marina; Dolara, Piero

      2009-01-08

      UV-induced oxidation damage seems to play a major role in a number of specific pathological conditions of intraocular tissues, such as cataract formation and retinal degeneration. Therefore, antioxidant and/or scavenger compounds might protect the eyes from UV-induced cellular damage. We previously reported that 4-coumaric acid (4-CA) is able to protect rabbit corneal-derived cells (SIRC) from UVB-induced oxidation damage. In this study we evaluated the protective effect of 4-CA against UVB-induced cell damage in rabbit cornea in vivo. Twelve male New Zealand albino rabbits were used; four rabbits were used as a control and received vehicle in one eye and 4-CA acid in the contralateral eye; eight rabbits were exposed to UVB rays (79.2mJ/cm(2)) and three days before to UV exposure each animal received 1 drop/day of vehicle in one eye and 1 drop/day of vehicle containing 4-CA (164ng) in the contralateral eye. Corneal and sclera tissues were removed and 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo) levels were measured. Superoxide dismutase (SOD) and xanthine oxidase (XO) activities were determined in aqueous humour. UVB-induced vessel hyper-reactivity was strongly reduced at 4 and 24h after UVB exposure after local treatment with 4-CA, 8-oxodGuo levels, a marker of oxidative DNA damage, were significantly increased (Peyes. Our results indicate that the administration of 4-CA protects eye tissues, thus reducing the harmful effect of UVB radiation at low concentration, probably through its free radical scavenging and antioxidant properties. Therefore, 4-CA may be useful in protecting the eye from free radical damage following UVB exposure from sunlight, UV lamps and welding torches.

    5. Biocompatibility of chitosan-coated iron oxide nanoparticles with osteoblast cells

      Directory of Open Access Journals (Sweden)

      Shi S

      2012-10-01

      Full Text Available Si-Feng Shi,1 Jing-Fu Jia,2 Xiao-Kui Guo,3 Ya-Ping Zhao,2 De-Sheng Chen,1 Yong-Yuan Guo,1 Tao Cheng,1 Xian-Long Zhang11Department of Orthopedic Surgery, Shanghai Sixth People’s Hospital, School of Medicine, 2School of Chemistry and Chemical Technology, 3Department of Medical Microbiology and Parasitology, School of Medicine, Shanghai Jiao Tong University Shanghai, ChinaBackground: Bone disorders (including osteoporosis, loosening of a prosthesis, and bone infections are of great concern to the medical community and are difficult to cure. Therapies are available to treat such diseases, but all have drawbacks and are not specifically targeted to the site of disease. Chitosan is widely used in the biomedical community, including for orthopedic applications. The aim of the present study was to coat chitosan onto iron oxide nanoparticles and to determine its effect on the proliferation and differentiation of osteoblasts.Methods: Nanoparticles were characterized using transmission electron microscopy, dynamic light scattering, x-ray diffraction, zeta potential, and vibrating sample magnetometry. Uptake of nanoparticles by osteoblasts was studied by transmission electron microscopy and Prussian blue staining. Viability and proliferation of osteoblasts were measured in the presence of uncoated iron oxide magnetic nanoparticles or those coated with chitosan. Lactate dehydrogenase, alkaline phosphatase, total protein synthesis, and extracellular calcium deposition was studied in the presence of the nanoparticles.Results: Chitosan-coated iron oxide nanoparticles enhanced osteoblast proliferation, decreased cell membrane damage, and promoted cell differentiation, as indicated by an increase in alkaline phosphatase and extracellular calcium deposition. Chitosan-coated iron oxide nanoparticles showed good compatibility with osteoblasts.Conclusion: Further research is necessary to optimize magnetic nanoparticles for the treatment of bone disease

    6. Elliptic Curve Integral Points on y2 = x3 + 3x ‑ 14

      Science.gov (United States)

      Zhao, Jianhong

      2018-03-01

      The positive integer points and integral points of elliptic curves are very important in the theory of number and arithmetic algebra, it has a wide range of applications in cryptography and other fields. There are some results of positive integer points of elliptic curve y 2 = x 3 + ax + b, a, b ∈ Z In 1987, D. Zagier submit the question of the integer points on y 2 = x 3 ‑ 27x + 62, it count a great deal to the study of the arithmetic properties of elliptic curves. In 2009, Zhu H L and Chen J H solved the problem of the integer points on y 2 = x 3 ‑ 27x + 62 by using algebraic number theory and P-adic analysis method. In 2010, By using the elementary method, Wu H M obtain all the integral points of elliptic curves y 2 = x 3 ‑ 27x ‑ 62. In 2015, Li Y Z and Cui B J solved the problem of the integer points on y 2 = x 3 ‑ 21x ‑ 90 By using the elementary method. In 2016, Guo J solved the problem of the integer points on y 2 = x 3 + 27x + 62 by using the elementary method. In 2017, Guo J proved that y 2 = x 3 ‑ 21x + 90 has no integer points by using the elementary method. Up to now, there is no relevant conclusions on the integral points of elliptic curves y 2 = x 3 + 3x ‑ 14, which is the subject of this paper. By using congruence and Legendre Symbol, it can be proved that elliptic curve y 2 = x 3 + 3x ‑ 14 has only one integer point: (x, y) = (2, 0).

    7. Effects of discharge operation regimes and magnetic field geometry on the in-out divertor asymmetry in EAST

      Energy Technology Data Exchange (ETDEWEB)

      Du, Hailong; Sang, Chaofeng [Key Laboratory of Materials Modification by Laser, Ion and Electron Beams (Ministry of Education), School of Physics and Optoelectronic Technology, Dalian University of Technology, Dalian 116024 (China); Wang, Liang [Key Laboratory of Materials Modification by Laser, Ion and Electron Beams (Ministry of Education), School of Physics and Optoelectronic Technology, Dalian University of Technology, Dalian 116024 (China); Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Bonnin, Xavier [LSPM-CNRS, Université Paris 13, Sorbonne Paris Cité, F-93430 Villetaneuse (France); Sun, Jizhong [Key Laboratory of Materials Modification by Laser, Ion and Electron Beams (Ministry of Education), School of Physics and Optoelectronic Technology, Dalian University of Technology, Dalian 116024 (China); Wang, Dezhen, E-mail: wangdez@dlut.edu.cn [Key Laboratory of Materials Modification by Laser, Ion and Electron Beams (Ministry of Education), School of Physics and Optoelectronic Technology, Dalian University of Technology, Dalian 116024 (China)

      2016-11-01

      Highlights: • The in-out divertor asymmetry is studied using SOLPS. • The discharge operation and the magnetic filed have a great influence on the divertor asymmetry. • The asymmetry is not obvious in low recycling regime as that in high recycling regime. - Abstract: This paper aims to investigate the reason why the divertor in-out asymmetry was not obvious as experimentally observed in EAST only considering the classical drifts from previous simulations (Guo et al., J. Nucl. Mater. 438 (2013) 280; Du et al., J. Nucl. Mater. 463 (2015) 485). With consideration of the classical drifts, a series of different typical discharge scenarios in EAST in different magnetic field geometries were simulated by using the SOLPS5.2 code package. The simulated results reveal that the classical drifts make a major contribution to the in-out divertor asymmetry in the high recycling regime (HRR) and partial detachment (one divertor target begins to detach, while the other divertor remains attached) regime. In comparison, in low recycling regime the classical drifts play a much smaller role in the contributions to the in-out divertor asymmetry, which can explain reasonably the reason for it in Guo et al. (J. Nucl. Mater. 438 (2013) 280). In addition, the magnetic field geometry also has a great impact on the classical drifts inducing the asymmetry; it is found that for lower single-null, upper single-null and connected double-null topologies, in HRR the classical drifts play an dominant role in the contribution to the in-out divertor asymmetry, while for a disconnected double null magnetic field configuration, they play a minor role, which is the reason why the in-out asymmetry was unobvious by considering the drifts in Du et al. (J. Nucl. Mater. 463 (2015) 485).

    8. Peripheral nerve disorder

      Institute of Scientific and Technical Information of China (English)

      1993-01-01

      930185 Hereditary motor and sensory neu-ropathy.GUO Yupu(郭玉璞),et al.Dept Neu-rol,PUMC Hosp Beijing,100730.Chin J Neurol& Psychiat 1992;25(5):261-263.The report consisted of 10 cases of hereditarymotor and sensory neuropathy(HMSN).Therewere 7 males and 3 females.Their ages rangedfrom 11 to 42(average 24.6)years,and ages ofonset varied from 7 to 34(average 17.3)years.Hereditary history was showed in 4 cases.Theclinical features of all 10 cases had peronealmuscular atrophy 8 of 10 cases also had involve-ment of the upper limbs,and 7 of 10 cases hadpesarcuatus.The conduction velocity was obvi-ously slow in 5 cases and slightly slow in the

    9. Enhanced methanol oxidation and oxygen reduction reactions on palladium-decorated FeCo@Fe/C core–shell nanocatalysts in alkaline medium

      CSIR Research Space (South Africa)

      Fashedemi, OO

      2013-12-01

      Full Text Available . Zhong, J. Luo, B. Fang, B. N. Wanjala, P. N. Njoki, R. Loukrakpam and J. Yin, Nanotechnology, 2010, 21, 062001. 39 C. L. Lee, H. P. Chiou, C. M. Syu, C. R. Liu, C. C. Yang and C. C. Syu, Int. J. Hydrogen Energy, 2011, 36, 12706–12714. 40 K. J. Mayrhofer..., 12, 1102–1106. 2 Y. W. Lee, M. Kim, Y. Kim, S. W. Kang, J. H. Lee and S. W. Han, J. Phys. Chem. C, 2010, 114, 7689–7693. 3 C. Zhu, S. Guo and S. Dong, J. Mater. Chem., 2012, 22, 14851–14855. 4 C. Jeyabharathi, P. Venkateshkhumar, J. Mathiyarasau and K...

    10. On the well-posedness of the Schrödinger-Korteweg-de Vries system

      Science.gov (United States)

      Guo, Zihua; Wang, Yuzhao

      We prove that the Cauchy problem for the Schrödinger-Korteweg-de Vries system is locally well-posed for the initial data belonging to the Sobolev spaces L(R)×H(R), and H(R)×H(R) ( s>-1/16) for the resonant case. The new ingredient is that we use the F-type space, introduced by the first author in Guo (2009) [10], to deal with the KdV part of the system and the coupling terms. In order to overcome the difficulty caused by the lack of scaling invariance, we prove uniform estimates for the multiplier. This result improves the previous one by Corcho and Linares (2007) [6].

    11. Revision of Eucorydia Hebard, 1929 from China, with notes on the genus and species worldwide (Blattodea, Corydioidea, Corydiidae)

      Science.gov (United States)

      Qiu, Lu; Che, Yan-Li; Wang, Zong-Qing

      2017-01-01

      Abstract The cockroach genus Eucorydia from China is revised. Five new species are described and illustrated: Eucorydia linglong sp. n., Eucorydia pilosa sp. n., Eucorydia splendida sp. n., Eucorydia guilinensis sp. n., and Eucorydia tangi sp. n.. Corydia purpuralis Kirby, 1903 and Eucorydia paucipilosa Woo, Guo & Feng, 1986 are confirmed to be junior synonyms of Eucorydia dasytoides (Walker, 1868). Eucorydia hilaris (Kirby, 1903) is newly recorded from China. This genus and currently known species from around the world are discussed. The status of Eucorydia maxwelli (Hanitsch, 1915) is revived. Corydia plagiata Walker, 1868 is confirmed to be a junior synonym of Eucorydia ornata (Saussure, 1864). A checklist, key, and photographs of members of this genus are provided. PMID:29187785

    12. Systemic oxidative stress to nucleic acids is unaltered following radioiodine therapy of patients with benign nodular goiter

      DEFF Research Database (Denmark)

      Bonnema, Steen J; Stovgaard, Elisabeth S; Fast, Søren

      2015-01-01

      morning urine (normalized against the creatinine concentration) at baseline, and 7 and 21 days after rhTSH (not followed by (131)I), and 7 and 21 days after (131)I therapy, respectively. RESULTS: The baseline urinary excretions of 8-oxoGuo and 8-oxodG were 2.20 ± 0.84 and 1.63 ± 0.70 nmol/mmol creatinine......, respectively. We found no significant changes in the excretion of any of the metabolites, neither after rhTSH stimulation alone nor after (131)I therapy. Also, no significant differences were found between the rhTSH group (low dose, median (131)I: 152 MBq) and the non-rhTSH group (high dose, median (131)I: 419...

    13. Design, synthesis, and evaluation of VEGFR-targeted macromolecular MRI contrast agent based on biotin–avidin-specific binding

      Directory of Open Access Journals (Sweden)

      Liu YJ

      2017-07-01

      Full Text Available Yongjun Liu,1 Xiaoyun Wu,1 Xiaohe Sun,1 Dan Wang,1 Ying Zhong,1 Dandan Jiang,1 Tianqi Wang,1 Dexin Yu,2 Na Zhang1 1School of Pharmaceutical Science, Shandong University, 2Department of Radiology Medicine, Qilu Hospital, Jinan, People’s Republic of China Abstract: Developing magnetic resonance imaging (MRI contrast agents with high relaxivity and specificity was essential to increase MRI diagnostic sensitivity and accuracy. In this study, the MRI contrast agent, vascular endothelial growth factor receptor (VEGFR-targeted poly (l-lysine (PLL-diethylene triamine pentacetate acid (DTPA-gadolinium (Gd (VEGFR-targeted PLL-DTPA-Gd, VPDG, was designed and prepared to enhance the MRI diagnosis capacity of tumor. Biotin-PLL-DTPA-Gd was synthesized first, then, VEGFR antibody was linked to biotin-PLL-DTPA-Gd using biotin–avidin reaction. In vitro cytotoxicity study results showed that VPDG had low toxicity to MCF-7 cells and HepG2 cells at experimental concentrations. In cell uptake experiments, VPDG could significantly increase the internalization rates (61.75%±5.22% in VEGFR-positive HepG2 cells compared to PLL-DTPA-Gd (PDG (25.16%±4.71%, P<0.05. In MRI studies in vitro, significantly higher T1 relaxivity (14.184 mM-1 s-1 was observed compared to Magnevist® (4.9 mM-1 s-1; P<0.01. Furthermore, in vivo MRI study results showed that VPDG could significantly enhance the tumor signal intensity and prolong the diagnostic time (from <1 h to 2.5 h. These results indicated that macromolecular VPDG was a promising MRI contrast agent and held great potential for molecular diagnosis of tumor. Keywords: MRI, contrast agent, VEGFR, biotin–avidin reaction, relaxivity

    14. Legenskap Masyarakat Bangkalan dan Unsur-­Unsur Pembentuknya

      Directory of Open Access Journals (Sweden)

      Iqbal Nurul Azhar

      2016-12-01

      Full Text Available Tujuan pelitian ini adalah menjelaskan legenskap di Kabupaten Bangkalan. Metode analisis data yang digunakan adalah analisis data interaktif yang diusulkan oleh Miles dan Huberman. Hasil penelitian menunjukkan bahwa jenis legenda yang terdapat pada masyarakat Bangkalan ada lima, yaitu asal muasal berdirinya sebuah daerah, kesaktian tokoh masyarakat yang telah meninggal dan kuburannya dianggap keramat, tempat-tempat mistik, penyebaran agama Islam, dan asal-usul munculnya sebuah budaya. Sebaran layer berdasarkan waktu terbentuknya, terbagi menjadi lima, yaitu legenda klasik, neoklasik, zaman tengah, zaman baru, dan masa kini. Berdasarkan hubungan cerita, Kabupaten Bangkalan dibagi menjadi empat kontur legenda, yaitu kontur utara, barat, selatan, timur, dan tengah. Penelitian ini juga menemukan dua fakta menarik yaitu adanya empat legenda yang melibatkan karakter perempuan Madura yang kuat bernama Bendoro Gung, Dewi Retnadi, Syarifah Ambami, dan Dewi Nawang Wulan. Keempat wanita ini sangat dihormati orang Madura padahal budaya Madura terkenal dengan patriarkatnya. Fakta kedua adalah jejak Pangeran Trunojoyo yang begitu terkenal di Madura namun tidak tampak menghiasi skap legenda masyarakat Bangkalan. The purpose of this study is to explain the Bangkalanese legendscape. The method used to analyze the data was the interactive data analysis, which was proposed by Miles and Huberman. From the data analysis, it has been found that there are five types of Bangkalan legends, namely: the origin of the establishment of a region, respectful leaders who died, living his/her sacred grave, mystical places, the spread of Islam, and the origins of the emergence of a culture. It has also been found the distributional of layers of legends existance namely: classics, neoclassic, middle ages, new era, and present layers. Based on the legend interrelations, it has been found four contours of legends, namely the north, west, the south, the east, and the central

    15. CHILDREN'S EDUCATION AND CHILDREN'S WORLD IN DİVANU LUGAT'İT TÜRK DİVANU LUGAT’İT TÜRK’TE ÇOCUK DÜNYASI VE ÇOCUK EĞİTİMİ

      Directory of Open Access Journals (Sweden)

      Zekerya BATUR

      2011-06-01

      Full Text Available This study was conducted as a survey method based on the review of the document. In this study Divanu Lugati't Türk was examined in terms of the concept of “child”, children's education and children's world. As a result of the study, it was determined that the child has own language, game world and view of education. In the book effectively used proverbs actions of the child's daily life. Mother dealt with the general education of the child, father dealt with vocational training. In addition, in the education of children mother played on important role in child’s education.In the book calls attention to the importance of child education, the environment. Children are growing games and toys concepts. The children are used the wrong superstitious beliefs from time to time Bu çalışma tarama modelinde olup doküman incelemesine dayalı olarak yapılmıştır. Çalışmada Divanu Lugati’t Türk, “çocuk” kavramı, çocuk eğitimi ve çocuk dünyası bağlamında incelenmiştir. Çalışmanın sonucunda çocuğun kendine özgü bir dili, oyun dünyası ve eğitim anlayışının olduğu belirlenmiştir. Eserde, çocuğun günlük yaşamdaki eylemleri atasözlerinde de etkili bir şekilde kullanılmıştır. Çocuğun genel eğitimiyle anne ilgilenirken, meslek eğitimiyle baba ilgilenmiştir. Bunun yanında çocuk eğitiminde annenin birinci derecede görevli, sorumlu olduğu görülmüştür.Eserde, çocuk eğitiminde çevrenin önemine dikkat çekilmiştir. Çocuğun oyun ve oyuncak kavramlarıyla büyüdüğü belirtilmiştir. Zaman zaman da çocuklarla ilgili yanlış batıl inançların kullanıldığı belirlenmiştir.

    16. Keberlanjutan dan Perubahan Pakarena Paolle

      Directory of Open Access Journals (Sweden)

      Fifie Febryanti Sukman

      2014-11-01

      Full Text Available Kehadiran Tarian Paolle dalam masyarakat Bantaeng merupakan latar belakangkebiasaan yang mengikuti tradisi leluhur mereka yang dilakukan sejak zaman dahulumelalui upacara adat yang memiliki Paolle Dance di dalamnya. Perubahan dari segibentuk Tarian Paolle terletak pada seorang penari, tempat, dan kostum. Para penariPaolle hari ini juga berbeda dari penari pertama pada zaman Kerajaan Paolle. Sepertipada hari-hari tertentu, para penari Raya Paolle adalah gadis remaja yang masihdalam keadaan suci atau tidak menstruasi, di saat para penari menjadi orang tua,mereka memiliki banyak pengalaman hidup dalam menari, sebuah praktik yangpada awalnya merupakan milik kerajaan, yang dapat dipilih dan dilihat oleh publikdi lapangan. Kostum atau pakaian yang digunakan para penari adalah irisan hitambodo yang sangat tipis dan sekarang hal itu berubah menjadi merah. KeberlanjutanTarian Paolle di masa sekarang harus dilihat dalam pernikahan atau baby shower.Masyarakat Bantaeng masih menunjukkan tarian ini dalam siklus hidup, misalnya,dalam acara pernikahan, sunat atau hanya berfungsi sebagai hiburan Tarian Paolle. Continuities and Changes of Pakarena Paolle. The background presence of PaolleDance in Bantaeng societies is a habit that follows the customs of their ancestors whohave practiced them since the time immemorial through the traditional ceremony that hasPaolle Dance in it. Changes in terms of the shape of Paolle Dance depend on a dancer,a venue, and costumes. Today’s Paolle Dancers are also different from the first dancers inKingdom era of Paolle. On the days of the Kingdom Paolle, dancers were teenage girls whowere still in a state of purity or not menstruation, but now dancers are the parents becausethey have a lot of life experiences in dancing, a practice that was originally familiarizedin the kingdom can be seen by the public in the field. Costume outfit that used a very thinblack wedge of bodo now turns into red. Paolle Dance sustainability in the

    17. PR Crisis Melalui Media Sosial

      Directory of Open Access Journals (Sweden)

      Gladys Carlina

      2017-07-01

      Full Text Available The background of this research is communication, new media, PR and PR Crisis. Fourth of this background has a close relationship, starting from communication, human in everyday life would require communication to receive and convey information, human can not be released from human life. The advancement of the times and the development of technology, causing people to communicate easily and the development of this era caused a new challenge for the PR and PR Crisis of a company, they should be able to maintain a positive image of the company in the minds of people. In this study using descriptive qualitative methodology, it contains many writings and drawings compared to the numbers. The purpose of this research is to know the strategy used by Pizza Hut in dealing with the issue of expired food. Penelitin results, social media is very positive impact on Pizza Hut in the recovery of food issues expired. The strategy used by the Pizza Hut Crisis PR is to utilize social media. Visible from the issue of expired food that disappeared in public and Pizza Hut restaurant until now crowded visited. Latar belakang dari penelitian ini yaitu komunikasi, media baru, PR dan PR Krisis. Keempat dari latar belakang ini mempunyai hubungan yang erat, dimulai dari komunikasi, manusia di dalam kehidupan sehari-hari tentunya memerlukan komunikasi untuk menerima dan menyampaikan informasi, manusia tidak bisa dilepaskan dari kehidupan manusia. Majunya perkembangan zaman dan perkembangan teknologi, menyebabkan manusia melakukan komunikasi dengan mudah dan perkembangan zaman ini menyebabkan adanya tantangan baru bagi para PR dan PR Krisis sebuah perusahaan, mereka harus bisa mempertahankan citra positif perusahaan di benak masyarakat. Dalam penelitian ini menggunakan metodologi kualitatif deksriptif, memuat banyak tulisan dan gambar dibandingkan angka-angka. Tujuan dari penelitian ini untuk mengetahui strategi yang digunakan oleh Pizza Hut dalam menangani isu makanan

    18. Ankara Üniversitesi Kriz Merkezine başvuran yas olguları üzerine bir çalışma

      OpenAIRE

      ŞENELMİŞ, Halil

      2006-01-01

      Ankara Üniversitesi Kriz Merkezi'ne BaşvuranYas Olguları Üzerine Bir ÇalışmaSosyal bir varlık olan insan yaşam süreci içerisinde zorlayıcı, yıpratıcı, tehdit edicibirçok olay ve sorunla karşılaşır. Her zaman sorunlar karşısında kullandığı çözüm yollarınınişe yaramadığını gören kişi, kendisini çaresiz hisseder. Bu yaşanan bir kriz durumudur. Krizçeşitli duygusal zorlanmalar sonunda meydana gelen akut ve süresi sınırlı bir dengebozukluğudur.Kişinin yaşamı boyunca karşılaştı...

    19. Konaklama İşletmelerinde Yiyecek-İçecek Maliyet Kontrolünün Önemi ve Akdeniz Bölgesindeki Konaklama İşletmelerinde Bir Anket Çalışması/Importance of the Food and Beverage Cost Control in the Lodging Companies and Qestionnaire-Based Study on the Lodging Co

      OpenAIRE

      Çam, Mustafa

      2014-01-01

      Konaklama işletmeleri, hizmet sektöründe varlıklarını sürdürdükleri için çoğunlukla soyut üretim yapmaktadırlar. Bu durum, konaklama işletmelerinin maliyetlerini kontrol etmelerini zorlaştırmakta ve zaman kaybına yol açmaktadır. Bu çalışmada, konaklama işletmelerinin ürettiği tek somut ürün olan yiyecek ve içecek ürünlerinin maliyetlerinin kontrolü üzerinde durulmuştur. Maliyet kontrolünün tanımı, faydaları, yöntemleri ve aşamaları genel hatlarıyla anlatılmaya çalışılmıştır. Bütün işletme tür...

    20. Kahramanmaraş Koşullarında Farklı Ekim Zamanlarının Isatis tinctoria ve Isatis buschiana Türlerinin Verim ve Bazı Agronomik Özellikleri Üzerine Etkileri

      OpenAIRE

      Çömlekcioğlu, N.; Efe, L.; Karaman, Ş.

      2014-01-01

      Bu çalışma, 2007-2008 ve 2008-2009 yetiştirme sezonunda Kahramanmaraş ekolojik koşullarında, farklı ekim zamanlarının (Ekim, Kasım, Şubat ve Mart) iki Isatis Isatis tinctoria ve Isatis buschiana türünün verim ve kalitesi üzerine etkisini belirlemek amacıyla tesadüf parselleri deneme desenine göre üç tekerrürlü olarak yürütülmüştür. Çalışmada Isatis türlerinin Kahramanmaraş iklim şartlarına en uygun ekim zamanının belirlenmesi amaçlanmıştır. İki yıllık sonuçlara göre, neredeyse incelenen bütün...

    1. KALIP ELEMANLARIN BİLGİSAYAR DESTEKLİ ÜÇ BOYUTLU TASARIMI

      Directory of Open Access Journals (Sweden)

      Kerim ÇETİNKAYA

      2000-02-01

      Full Text Available Saç metal kalıplarının klasik yöntemlerle tasarımı uzun süreli hesaplamalar ve çizimlerden oluşmaktadır. Kalıp tasarımında pekçok elemanın seçimi ve çizimi benzer işlemlerin tekrarı olduğundan zaman alıcıdır. Bu çalışmada, AutoCAD paket programına uyarlanmış olan AutoLISP kullanılarak bir kalıp tasarım programı hazırlanmıştır. Yapılan çalışma ile saç metal kalıplarının tasarımı ve boyutlandırılması gerçekleştirilmiştir.

    2. Islam Dalam Karya R. Ng. Rangga Warsita

      Directory of Open Access Journals (Sweden)

      Pardi Pardi

      2008-12-01

      Full Text Available Ranggawarsita as a cultural observer in his era, has a distinctive feature of his own compared to other Java poets. The name of R. Ngabei Ranggawarsita has been attached so much with the life of Javanese until this time. Zaman edan concept in his work Sera/ Kalatidha has become an icon of Javanese thought over the time. The poet has to be known as a Java poet. Whereas, since young Ranggawarsita lived in Islamic culture situation in complience with the dynamic of Javanese life journey. That way, Ranggawarsita can put the Javanese values correlated with Islamic theory in order. Ranggawarsita has a deep understanding toward Javanese and Islamic culture that are expressed in his works, such as Serat Kalatidha, Serat Supanalaya, and Sera/Wedharaga. The analysis of this paper proves that Ranggawarsita can express harmony thought or the equilibrium between Javanese and Islamic thought.

    3. Sosyal Pazarlama Literatür İncelemesi: Prensipler ve Teknikler Kapsamında Ele Alınan Temel Konular (1971-2014)

      OpenAIRE

      Kitapcı, Olgun; Dörtyol, İbrahim Taylan; Gülmez, Mustafa

      2018-01-01

      SosyalPazarlama kavramının doğduğu tarihten günümüze yazılmış ve Web of Science (WOS)veri tabanında yayınlanmış makalelerin, Lee ve Kotler’in 2011 yılındayazdıkları kitapta yer alan sınıflandırma çerçevesinde yorumlanmasını amaçlayanbu çalışma sözkonusu alanda zaman içerisinde hakim olan araştırma eğilimlerini ortayakoymaktadır. Bu kapsamda, ilgili veri tabanında yer alan makalelerin tamamıtaranmış ve sınıflandırılmıştır. Makalelerin temel odakları sosyal pazarlamabağlamında ele alınan temel ...

    4. سینمای ایران

      OpenAIRE

      EMAMİ, SABER

      2016-01-01

      Bu makale'de başlangıçtan İran İslâm devrimi ve İran-Irak savaşına kadar İran sineması incelenmiştir. Sinema tekniği Kaçar Şahı Nâsıruddîn Şah ve oğlu Muzafferüddin Şah’ın Avrupaya seferleriyle, çağdaş uygarlık ürünü olarak İran’a getirildi. Farsça ilk sesli sinema Rıza Şah zamanında “Dohter-i Lor: Lor Kızı” adlı film ile başladı. Ardından devlet tarafından teşvik edilen bir sinema, “olay”, “ahlak”, “müzik” ve “cinsel cazibe” ögelerine danyanarak şekillenmiştir. Bu sinema, daha çok dinse...

    5. ظاهرة النحت في اللغة العربية قديماً وحديثاً

      Directory of Open Access Journals (Sweden)

      Iswah Adriana

      2014-05-01

      Full Text Available Setiap bahasa mempunyai hubungan yang sangat erat dengan penuturnya. Begitu pula yang terjadi dalam perkembangan bahasa Arab. Teori perkembangan bahasa menganggap bahwa perkembangan bahasa sangat terpengaruh oleh lingkungan di mana bahasa berkembang. Interaksi suatu bahasa dengan bahasa lain dapat melahirkan wujud baru yang tidak ditemukan sebelumnya. Demikian pula yang terjadi dalam An-naht ini. An-naht merupakan cabang isytiqaq dalam pembentukan kata baru untuk makna yang baru pula. Tuntutan membuat An-Naht di zaman modern semakin meningkat, khususnya setelah bangsa Arab mulai mentrasfer sejumlah ilmu pengetahuan ke dalam bahasa Arab. An-Naht merupakan langkah kreatif meringkas dan mempermudah pengucapan serangkaian kata. Bentuk an-Naht secara sepintas mempunyai kemiripan penyingkatan dalam bahasa Indonesia (Akronim. Makalah ini akan mengungkap fenomena pembentukan kata dengan menggunakan an-Naht sebagai bagian dari isytiqaq , baik itu dilihat dari definisi, tujuan, cara pembentukan, dan macam-macamnya pada masa kuno dan modern.

    6. KISMİ DİFERANSİYEL DENKLEMLERİN PARALEL ÇÖZÜM YÖNTEMLERİ

      Directory of Open Access Journals (Sweden)

      Korhan KARABULUT

      1998-03-01

      Full Text Available Kısmi diferansiyel denklemler bilimin ve mühendisliğin hemen her alanında ortaya çıkar. Bu denklemlerin çözümü için harcanan bilgisayar zamanı, herhangi başka bir problem sınıfını çözmek için harcanan zamandan daha fazladır. Bu nedenle, kısmi diferansiyel denklemler, çok büyük bir işlemci gücü sağlayan paralel bilgisayarlar üzerinde çözümlenmeye çok uygundur. Bu çalışmada kısmi diferansiyel denklemlerin Jacobi, Gauss-Siedel, SOR (Ardışık aşırı yumuşatma ve SSOR (Simetrik SOR algoritmalarıyla paralel olarak çözülmesi incelenmiştir.

    7. Türkiye'de Politik Ritüeller Political Rituals In The Turkish

      Directory of Open Access Journals (Sweden)

      Kürşat ÖNCÜL

      2013-07-01

      rkiye Cumhuriyeti içerisinde de belirtilenler doğrultusunda yasal ve yasa dışı kabul edilen çok sayıda tören ve bu törenlere bağlı gerçekleştirilen ritüeli görmek mümkündür. Bu törenlerin katılımcıları törenlerinin ve ritüellerinin ilk eylem anını, gerçekleşme zamanını ve çoğunlukla gerçekleştiği mekânı yeniden var etme, yaşatma ilkesi içerisinde tekrarlamaktadırlar. Her yeni tekrar, grup bilincini desteklemekte ve yeni katılımcıyı bu andan pay sahibi olma yönünde güdülemektedir. Katılımcı için bu yönüyle özel bir kutsiyete sahip olan ritüeller, yöneticiler açısından zaman zaman sadece bir grubun anma programı zaman zaman da bir kitlenin ayaklanma girişiminin ilk adımlarına dönüşmektedir.Belirtilenler çerçevesinde bu çalışmada, Türkiye Cumhuriyeti’nin kuruluşu, iktidarı elinde bulunduranların temel kabulleri, mitolojide törenin yeri ve anlamı son olarak da belirtilenlerden hareketle Türkiye’deki politik ritüellerin yeri verilmeye çalışılmıştır.

    8. Produção Offshore na Bacia de Campos (RJ: a perspectiva da Psicologia do Trabalho

      Directory of Open Access Journals (Sweden)

      Alexandre de Carvalho Castro

      2013-01-01

      Full Text Available O objetivo deste artigo é examinar a dinâmica psicológica dos trabalhadores offshore da Bacia de Campos (RJ. A técnica de grupo focal, enquanto metodologia de base qualitativa, foi utilizada para explorar opiniões, percepções, conceitos, atitudes e valores dos petroleiros. Seis grupos focais consistiram no procedimento metodológico por meio do qual foram colhidas informações sobre as condições de trabalho embarcado. RESULTADOS: A análise do processo de trabalho em plataformas marítimas, com sua variabilidade e dificuldade, segundo a perspectiva da Psicologia do Trabalho, evidenciou que o tempo de trabalho, a vida e os ganhos dos trabalhadores são ambíguos, assimétricos e dissociados.

    9. Optical enhancement effects of plasmonic nanostructures on organic photovoltaic cells

      KAUST Repository

      Park, Hui Joon

      2015-04-01

      © 2015 Hui Joon Park and L. Jay Guo. Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. All rights reserved. In this article, the optical enhancement effects of plasmonic nanostructures on OPV cells were reviewed as an effective way to resolve the mismatch problems between the short exciton diffusion length in organic semiconductors (around 10 nm) and the large thickness required to fully absorb sunlight (e.g. hundreds of nanometers). Especially, the performances of OPVs with plasmonic nanoparticles in photoactive and buffer layers and with periodic nanostructures were investigated. Furthermore, nanoimprint lithography-based nanofabrication processes that can easily control the dimension and uniformity of structures for large-area and uniform plasmonic nanostructures were demonstrated.

    10. 7th China Conference on Wireless Sensor Networks

      CERN Document Server

      Cui, Li; Guo, Zhongwen

      2014-01-01

      Advanced Technologies in Ad Hoc and Sensor Networks collects selected papers from the 7th China Conference on Wireless Sensor Networks (CWSN2013) held in Qingdao, October 17-19, 2013. The book features state-of-the-art studies on Sensor Networks in China with the theme of “Advances in wireless sensor networks of China”. The selected works can help promote development of sensor network technology towards interconnectivity, resource sharing, flexibility and high efficiency. Researchers and engineers in the field of sensor networks can benefit from the book. Xue Wang is a professor at Tsinghua University; Li Cui is a professor at Institute of Computing Technology, Chinese Academy of Sciences; Zhongwen Guo is a professor at Ocean University of China.

    11. Power absorption of high-frequency electromagnetic waves in a partially ionized magnetized plasma

      International Nuclear Information System (INIS)

      Guo Bin; Wang Xiaogang

      2005-01-01

      Power absorption of high-frequency electromagnetic waves in a uniformly magnetized plasma layer covering a highly conducting surface is studied under atmosphere conditions. It is assumed that the system consists of not only electrons and positive ions but negative ions as well. By a general formula derived in our previous work [B. Guo and X. G. Wang, Plasma Sci. Tech. 7, 2645 (2005)], the total power absorption in the plasma layer with multiple reflections between an air-plasma interface and the conducting surface is computed. The results show that although the existence of negative ions greatly reduces the total power absorption, the magnetization of the plasma can, however, partially enhance it. Parameter dependence of the effects is calculated and discussed

    12. Retention/sorption and geochemical modelling

      Energy Technology Data Exchange (ETDEWEB)

      Arcos, D.; Grandia, F.; Domenech, C. [Enviros Spain, S.L., Barcelona (Spain); SCK-CEN, Mol (Belgium); Sellin, P. [SKB - Swedish Nuclear Fuel and Waste Management, SE, Stockholm (Sweden); Hunter, F.M.I.; Bate, F.; Heath, T.G.; Hoch, A. [Serco Assurance, Oxfordshire (United Kingdom); Werme, L.O. [SKB - Svensk Karnbranslehantering AB, Stockholm (Sweden); Bruggeman, C.; Maes, I.A.; Breynaert, E.; Vancluysen, J. [Leuven Katholieke Univ., Lab. for Colloid Chemistry (Belgium); Montavon, G.; Guo, Z. [Ecole des Mines, 44 - Nantes (France); Riebe, B.; Bunnenberg, C.; Meleshyn, A. [Leibniz Univ. Hannover, Zentrum fur Strahlenschutz und Radiookologie, Hannover (Germany); Dultz, S. [Leibniz Univ. Hannover, Institut fur Bodenkunde, Hannover (Germany)

      2007-07-01

      This session gathers 4 articles dealing with: the long-term geochemical evolution of the near field of a KBS-3 HLNW repository: insights from reactive transport modelling (D. Arcos, F. Grandia, C. Domenech, P. Sellin); the investigation of iron transport into bentonite from anaerobically corroding steel: a geochemical modelling study (F.M.I. Hunter, F. Bate, T.G. Heath, A. Hoch, L.O. Werme); SeO{sub 3}{sup 2-} adsorption on conditioned Na-illite: XAS spectroscopy, kinetics, surface complexation model and influence of compaction (C. Bruggeman, A. Maes, G. Montavon, E. Breynaert, Z. Guo, J. Vancluysen); the influence of temperature and gamma-irradiation on the anion sorption capacity of modified bentonites (B. Riebe, C. Bunnenberg, A. Meleshyn, S. Dultz)

    13. GİRİŞİMCİLİK EĞİLİMİNİN KUŞAK FARKINA GÖRE İNCELENMESİ

      OpenAIRE

      KELEŞ, Hatice Necla

      2013-01-01

      Benzer bir zaman aralığında doğmuş, benzer yaş ve hayat dönemlerini paylaşarak, belirli bir dönemin olayları tarafından şekillenmiş insan topluluğu olarak ifade edilen kuşakların kendilerine özgü özellikleri, değer yargıları ve tutumlarının olduğu görüşünden yola çıkarak, girişimcilik eğilimlerinin de farklılaşabileceği düşüncesi bu çalışmanın ortaya çıkmasında etkili olmuştur. Bu araştırmanın temel amacı girişimcilik eğilimini kuşak farkına göre incelemektir. Araştırma kapsamında İstanbul il...

    14. PERAN GANDA PEDAGANG PEREMPUAN DI PASAR SENI MERTHA NADI LEGIAN, BALI

      Directory of Open Access Journals (Sweden)

      Wayan Hesty Mayaswari

      2015-11-01

      Full Text Available Zaman sekarang banyak perempuan telah berpartisipasi dalam sektor publik. Namun hal ini dapat menimbulkan kon ik pembagian waktu bagi perempuan, yaitu dalam tugas domestik dan aktivitas sosial sebagai perempuan Bali. Tujuan penelitian ini adalah untuk mengetahui pengaruh jumlah tanggungan keluarga, pendapatan nonkerja, dan pelaksanaan kegiatan adat istiadat terhadap alokasi waktu perempuan pedagang cenderamata di Pasar Seni Mertha Nadi Legian, baik secara simultan maupun secara parsial. Data dikumpulkan melalui observasi, kuesioner, dan wawancara tidak terstruktur. Teknik sampling yang digunakan adalah systematic random sampling menggunakan sampel sebanyak 70 responden. Hasil penelitian menunjukkan bahwa perubahan pendapatan nonkerja tidak memengaruhi perubahan konsumsi waktu luang dan alokasi waktu kerja perempuan di sektor publik. Jika intensitas untuk kegiatan adat sedang tinggi, maka waktu mereka untuk bekerja akan berkurang. Pedagang perempuan di Pasar Seni Mertha Nadi Legian selalu memiliki alasan untuk tetap bekerja selain banyaknya pekerjaan domestik yang seharusnya mereka lakukan demi pengembangan diri dan kesejahteraan keluarganya.

    15. Penerapan Metode Composite Performance Index (CPI Pada Pemilihan Hotel Di Kota Lubuklinggau

      Directory of Open Access Journals (Sweden)

      Andri Anto Tri Susilo

      2017-12-01

      Full Text Available Seiring dengan kemajuan zaman, kemajuan teknologi informasi juga semakin berkembang pesat. Perkembangan teknologi informasi, memiliki dampak besar pada berbagai bidang kehidupan masyarakat baik dari segi sosial, ekonomi, pendidikan, pembangunan, dan pariwisata. Salah satu unsur penting yang mendukung sektor pariwisata adalah adanya hotel. Hotel sebagai sarana akomodasi umum sangat membantu wisatawan yang berkunjung dengan menyediakan layanan penginapan. Keragaman hotel sering membuat para wisatawan kesulitan dalam menentukan hotel yang akan dipilih sebagai tempat menginap. Sistem pendukung keputusan adalah model yang dibangun untuk memecahkan masalah terstruktur. Composite Performance Index (CPI adalah metode yang umum digunakan dalam proses pengambilan keputusan adalah. Metode CPI menggunakan pemecahan masalah dengan sistem Multiple Criteria Decision Making (MCDM yang menentukan urutan atau prioritas dalam analisis multikriteria. Hasil akhir dari penelitian ini adalah terciptanya sistem pendukung keputusan yang menghasilkan informasi mengenai peringkat hotel yang dapat dijadikan tempat referensi untuk tetap memperhatikan beberapa kriteria, termasuk tarif kamar, jarak ke pusat kota, fasilitas dan layanan.

    16. ANALISIS PENYEBAB BANJIR KALI JUANA

      Directory of Open Access Journals (Sweden)

      Teguh Marhendi

      2017-04-01

      Full Text Available Kali Juana yang berada di Kabupaten Pati dan Kudus serta sebagian kecil di Kabupaten Grobogan dan Blora, merupakan kawasan banjir. Kejadian banjir di Kali Juana, sudah menjadi rutinitas setiap musim hujan.Dari Januari sampai bulan Mei 2016tercatat terjadi 11 kejadian banjir dibeberapa wilayah, seperti Kecamatan Kaliwungu, Undaan dan Mejobo (Kab. Kudus serta Pati, Margorejo dan Juwana (Kab. Pati. Kali Juana merupakan bifurkasi Kali Serang pada Pintu Wilalung, yang berfungsi sebagai pintu pengatur banjir (dibangun pada zaman Belanda tahun 1918, melalui Kali Babalan menuju ke Kali Juana. Tulisan inidimaksudkan untuk menganalisis penyebab kejadian banjir di Kali Juana. Analisis dilakukan dengan melakukan kajani dan analisis hujan serta mekanisme aliran. Hasil analisis menunjukkan bahwa kondisi Kali Juana dari pertemuan Kali Logung di pintu Wilalung sampai hilir telah mengalami pendangkalan akibat kemiringan dasar atau topografi yang landai, dan mengakibatkan mudah terjadi sedimentasi sehingga mengurangi kapasitas pengaliran. Hal ini menyebabkan luapan banjir sering menggenangi wilayah Kabupaten Kudus dan Pati.

    17. AutoLISP KULLANILARAK ÜÇ KOLLU ROBOTUN HAREKET SİMÜLASYONU

      OpenAIRE

      BOZDEMİR, Mustafa; ÇETİNKAYA, Kerim

      2000-01-01

      İstenilen görev ve amaca en uygun biçimde robot geliştirmek tasarımcılar için çok büyük önem taşır. Diğer bir deyişle üzerinde çok uğraşıldığı halde tasarlanan robotlar her zaman görev yerlerinde başarılı olmayabilir. Bu nedenle tasarımı düşünülen robot sistemlerin imalinden önce, bir simülasyon programı hazırlanarak, iş alanının incelenmesi, yörünge planlamasının yaptırılması, tasarımcıya eğer var ise yanlışlıkların daha robot yapılmadan giderilmesi imkanını sağlayabilir. Bu konuda AutoCAD p...

    18. Viking gemiciliği

      OpenAIRE

      ÖZBEY, Muhammet Talha

      2015-01-01

      Moğolların, hükümdarları Cengiz Han (1206-1227) önderliğinde karada kat ettiği mesafenin bir benzerine, bundan yaklaşık dört yüzyıl önce İskandinavlar Viking çağında (İS. 793-1066) zamanın bilinen ve ötesindeki coğrafya içerisindeki akınlarıyla ulaşmışlardı. Farklı bölgelerdeki İskandinavların bir kısmı akıncı hüviyetine bürünmüşken bir diğer kısmı da tüccar kimliğindedir. Ticaret ile uğraşan İskandinavların yerleşimleri doğal sonuç olarak ortaya çıkarken, istilaları takip eden süreç...

    19. Türkiye'de gülmenin dönüşümü: 1970 ve 2000'li yıllarda gülmenin dönüşümü - Komedi filmlerinin karşılaştırmalı bir analizi

      OpenAIRE

      Şahinalp, Saliha Deniz

      2010-01-01

      152 pages Gülme, insanlık tarihinin her döneminde temel insan edimi olarak var olmuştur. İnsanın ilk defa ne zaman ve neden güldüğünü bilmesek de; gülmenin, insanın çevresine anlam atfetme aracı olan kültürün bir parçası olduğunu biliyoruz. Bu bağlamda Gülme edimini direk olarak kültürel bağlamda düşünebiliriz. Gülmenin kendisi hiç değişmese de, insanoğlunun neye güldüğü çağdan çağa ve kültürden kültüre hatta aynı kültür içinde on yıldan on yıla, sürekli değişim halindedir. Burdan hareketl...

    20. İMAGOLOJİ / IMAGOLOGY

      Directory of Open Access Journals (Sweden)

      Ertan ENGİN

      2012-07-01

      Full Text Available Karşılaştırmalı edebiyat çalışmaları içinde bir alt disiplin, yan dal olarak ortaya çıkan ve zaman geçtikçe araştırmacılar tarafından daha çok ilgi gören imagoloji, toplumların birbirlerini nasıl gördüklerini inceleyen ve bunu da çoğunlukla/öncelikle kendisi için en elverişli malzemeyi sağlayacak edebiyat eserleri üzerinden gerçekleştiren bir araştırma sahasıdır. Bu yazıda söz konusu araştırma sahasının kökeninde yer alan ‘imaj’ kavramı ile birlikte, imagolojinin kapsam ve metodolojisinde dikkatimizi çeken bazı noktalara değinilmiştir.

    1. 2. Sino-German workshop on fuel cells. Book of abstracts

      Energy Technology Data Exchange (ETDEWEB)

      NONE

      2003-07-01

      The CD-ROM contains the content of 13 lectures and 19 proposals for joint projects, which were presented on the second Sino-German Workshop on fuel cells. The topics of the 13 lectures are: Ab-initio calculations of oxygen species on low-index platinum surfaces (Pachenko, M.T.M. Koper, T.E. Shubina, S.J. Mitchell, E. Roduner). Cross-Linked (Composite) Polyaryl Blend Membranes for Membrane Fuel Cells. (J.A. Kerres, A. Ullrich, W. Zhang, M. Hein, V. Gogel, L. Joerissen, Th. Frey, A. Friedrich). Performance and Methanol Permeation of Direct Methanol Fuel Cells: Dependence on Operating Conditions and on Electrode Structure(V. Gogel, Th. Frey, K.A. Friedrich, L. Joerissen, J. Garche, Z. Yongsheng). Experimental Investigation of Flow Bed Configuration Effect on Performance of Liquid Feed Direct Methanol Fuel Cells. (H. Guo, C.F. Ma, M.H. Wang, F. Ye, J. Yu, Y. Wang, C.Y. Wang). Improvement of MEAs for DMFC by a tuned production sequence assisted by mathematical modelling (Lindermeir, G. Rosenthal, U. Kunz, U. Hoffmann). Performance of the self-breathing air DMFC with solution grafted PVDF-g-PSSA membranes (X. Qiu, G. Guo, W. Li, W. Zhu, L. Chen). Modeling the Effects of Methanol Crossover on DMFC (J. Zhang, Y. Wang). The characteristics of 40 kW PEM fuel cell engine for vehicle(M. Hou, P. Ming, H. Zhang). A New and Simple Method for Preparing Biocathode in Biofuel Cells (D. Sun, C. Cai, X. Li, W. Xing, T. Lu). Nonlinear Model Reduction of a Dynamic Two-dimensional Molten Carbonate Fuel Cell Model (M. Mangold, M. Sheng). Recent Advances in Design and Fabrication of Low-Temperature Solid Oxide Fuel Cells (C. Xia, G. Meng). Novel CVD Techniques for Micro- and IT-SOFC Fabrication (G. Meng, H. Song, Q. Dong, D. Peng). Fundamental properties of La{sub 0.6}Sr{sub 0.4}Co{sub 0.8}Fe{sub 0.2}O{sub 3-{delta}} at high temperatures (S. Wang, T.-L. Wen).

    2. Dilemmas of Democratization in Turkey with Special Reference to “Modernization From Above” / Yukarıdan Modernleşme Bağlamında Türkiye’de Demokratikleşme Çıkmazı

      Directory of Open Access Journals (Sweden)

      H. Emre BAĞCE

      2015-01-01

      Full Text Available The social and political structure of the Ottoman Empire and the basic principles upon which the Turkish modernization was established are to be strictly scrutinized in order to understand the problems concerning the institutionalization of democracy in Turkey. In this article, which covers the period from the establishment of the new state to 1980s, it is argued that the implementation of the “modernization from above” has undermined the consolidation of democratic institutions. That the politics in Turkey has a narrow social base exaggerated the question of institutionalization and widened the controversy between the political/bureaucratic/ military elite and the people. The populist policies which were favored especially by Democrat Party and its heirs could not surmount the issue. On the contrary, reproducing patrimonial relations, it prevented the formation of a civil and political society which might be regarded as a constituting part of democracy. / Türkiye’de demokrasinin kurumsallaşması ile ilgili sorunların anlaşılabilmesi için Osmanlı toplum ve siyasal yapısının dikkate alınması ve Türk modernleşmesinin üzerine kurulduğu temel ilkelerin sıkı şekilde gözden geçirilmesi gerekir. Yeni devletin kuruluşundan 1980’lere kadarki dönemi kapsayan bu makalede Türk modernleşmesinin “yukarıdan aşağıya” doğru uygulanışının demokrasinin kurumsallaşmasını ve sağlam dayanaklar üzerinde yükselmesini engellediği tartışılmıştır. Siyasetin toplumsallaşamamış olması, dolayısıyla dar bir çerçeve içinde kalması bu zaafın derinleşmesine ve siyasal, bürokratik ve askeri elitle halk arasındaki karşıtlığın kronikleşmesine yol açmıştır. Zaman zaman uygulanan popülist politikalar da bu sorunu aşamadığı gibi, patrimonyal ilişkileri yeniden üreterek demokrasinin gelişimi ile sıkı şekilde bağlantılı bulunan sivil ve siyasal bir toplumun oluşumunu engellemiştir.

    3. Orta Ölçekli Bir İşletmenin Enerji İzleme Sisteminin Tasarlanması

      Directory of Open Access Journals (Sweden)

      Erdal Irmak

      2012-02-01

      Full Text Available Bu uygulamada, orta ölçekli bir işletmenin gerçek zamanlı ve geçmişe yönelik enerji takibinin bilgisayar ara yüzünden izlenmesi gerçekleştirilmiştir. Enerjinin ölçülmesi için akım ve gerilim bilgilerini Programlanabilir Lojik Kontrolörün ( PLC algılayacağı seviyeye getiren bir kart tasarlanmıştır. Bu karttan alınan akım ve gerilim bilgileri, PLC'nin analog kanalları ile okunmaktadır. Sistemin güç katsayısının algılanması için, bir sıfır geçiş detektörü tasarlanmıştır. Sıfır geçiş detektöründen elde edilen sinyaller arasındaki zaman farkı FM 350-1 sayıcı modül kullanılarak ölçülmüştür. Alınan bilgiler, PLC tarafından RS485/RS232 dönüştürme protokolü kullanarak, bilgisayarın seri iletişim kanalı aracılığı ile veritabanına aktarılmaktadır. Elde edilen veriler, C# programlama dili kullanılarak tasarlanan bir arayüz ile anlık takip edilebilmektedir. Elde edilen veriler sürekli olarak kaydedilerek geçmişe yönelik enerji analizleri yapma olanağı sağlanmıştır. Böylece, istenildiğinde belirlenen zaman aralığında kullanılan aktif, reaktif ve görünür güçler gözlemlenebilmektedir. Geçmişe yönelik enerji izleme sistemi kullanılarak işletmelerin fazla enerji harcadığı zamanlar tespit edilebilmektedir. Böylece, yoğun çalışma saatleri enerjinin ucuz olduğu zamanlara kaydırılarak kullanılan enerjinin işletmeye olan maliyetinin azaltılması gibi olanaklar sağlanmaktadır.

    4. Oxidatively generated DNA/RNA damage in psychological stress states

      DEFF Research Database (Denmark)

      Jørgensen, Anders

      2013-01-01

      age-related somatic disorders. The overall aim of the PhD project was to investigate the relation between psychopathology, psychological stress, stress hormone secretion and oxidatively generated DNA and RNA damage, as measured by the urinary excretion of markers of whole-body DNA/RNA oxidation (8...... between the 24 h urinary cortisol excretion and the excretion of 8-oxodG/8-oxoGuo, determined in the same samples. Collectively, the studies could not confirm an association between psychological stress and oxidative stress on nucleic acids. Systemic oxidatively generated DNA/RNA damage was increased......Both non-pathological psychological stress states and mental disorders are associated with molecular, cellular and epidemiological signs of accelerated aging. Oxidative stress on nucleic acids is a critical component of cellular and organismal aging, and a suggested pathogenic mechanism in several...

    5. Current status and progress of digital orthopaedics in China

      Directory of Open Access Journals (Sweden)

      Guo-Xian Pei

      2014-07-01

      Full Text Available Based on the development of digital medicine and digital anatomy, the concept of “digital orthopaedics” was raised by Pei Guo-Xian in China in 2006. The most striking feature of digital orthopaedics is the combination of basic and clinical orthopaedic knowledge with digital technology. In this review, we summarised the development of digital orthopaedics in China in recent years with respect to: the foundation of the Chinese Association of Digital Orthopedics, virtual human project (VHP, three-dimensional (3D reconstruction, finite element simulation, navigation in orthopaedic operations, and robot-assisted orthopaedic operations. In addition, we briefly reviewed digital orthopaedics in world leading institutes. We also looked into the future of digital orthopaedics in China and proposed the major challenges in digital technology and application in orthopaedics.

    6. Entanglement criterion for tripartite systems based on local sum uncertainty relations

      Science.gov (United States)

      Akbari-Kourbolagh, Y.; Azhdargalam, M.

      2018-04-01

      We propose a sufficient criterion for the entanglement of tripartite systems based on local sum uncertainty relations for arbitrarily chosen observables of subsystems. This criterion generalizes the tighter criterion for bipartite systems introduced by Zhang et al. [C.-J. Zhang, H. Nha, Y.-S. Zhang, and G.-C. Guo, Phys. Rev. A 81, 012324 (2010), 10.1103/PhysRevA.81.012324] and can be used for both discrete- and continuous-variable systems. It enables us to detect the entanglement of quantum states without having a complete knowledge of them. Its utility is illustrated by some examples of three-qubit, qutrit-qutrit-qubit, and three-mode Gaussian states. It is found that, in comparison with other criteria, this criterion is able to detect some three-qubit bound entangled states more efficiently.

    7. Chinese Studies and Beyond

      DEFF Research Database (Denmark)

      Brødsgaard, Kjeld Erik

      2013-01-01

      Many different conceptual approaches and models have been used to analyze contemporary Chinese history and politics. Some of the more commonly used include "totalitarianism", "two-line struggle", "clientelism", "tendency analysis", "political culture", "interest group politics", "bureaucratic...... politics", "corporatism", "civil society", "fragmented authoritarianism", etc. (Brødsgaard, 1989; Guo 2013). This paper will survey these approaches in order to place the analysis of the contemporary Chinese politics and history in a comparative perspective. A survey of the field will remind us...... that contemporary China studies have increasingly developed into a collective effort and that no scholar conducts his/her research in a vacuum devoid of dept to other contributions in the field. The paper will focus on the period since the Cultural Revolution. Consequently, we will not attempt a discussion...

    8. Aminothiols linked to quinoline and acridine chromophores efficiently decrease 7,8-dihydro-8-oxo-2'-deoxyguanosine formation in γ-irradiated DNA

      International Nuclear Information System (INIS)

      Laayoun, A.; Coulombeau, C.; Constant, J.F.; Lhomme, J.; Berger, M.; Cadet, J.

      1994-01-01

      In a search for more active radioprotective compounds, we have prepared and examined a series of model molecules in which the radioprotective β-aminothiol unit (free or derivatized as acetate or phosphorothioate) is tethered to the DNA-binding chromophores quinoline and acridine through links of variable length. The modifying activity of these 'hybrid' molecules was estimated by measuring the formation of 8-oxo-2'-deoxyguanosine (8-oxodGuo) in double-strand DNA upon exposure to γ-rays in oxygen-free solution in the presence of the drugs. We show that all hybrid molecules protect the guanine moiety from oxidation more efficiently than the parent β-aminothiol units. The degree of protection is the highest for the molecules in which the thiol is linked to the strong binding intercalator acridine through a long polyaminochain. (author)

    9. Elevated levels of urinary markers of oxidatively generated DNA and RNA damage in bipolar disorder

      DEFF Research Database (Denmark)

      Munkholm, Klaus; Poulsen, Henrik Enghusen; Kessing, Lars Vedel

      2015-01-01

      OBJECTIVES: The pathophysiological mechanisms underlying bipolar disorder and its multi-system nature are unclear. Oxidatively generated damage to nucleosides has been demonstrated in metabolic disorders; however, the extent to which this occurs in bipolar disorder in vivo is unknown. We...... investigated oxidatively generated damage to DNA and RNA in patients with bipolar disorder and its relationship with the affective phase compared with healthy control subjects. METHODS: Urinary excretion of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) and 8-oxo-7,8-dihydroguanosine (8-oxoGuo), markers...... of oxidatively generated DNA and RNA damage, respectively, was measured in 37 rapid cycling patients with bipolar disorder and in 40 age- and gender-matched healthy control subjects. Employing a longitudinal design, repeated measurements of both markers were evaluated in various affective phases in patients...

    10. Molecular dynamics simulations of phase separation in the presence of surfactants

      DEFF Research Database (Denmark)

      Laradji, Mohamed; Mouritsen, Ole G.; Toxvaerd, Søren

      1994-01-01

      The dynamics of phase separation in two-dimensional binary mixtures diluted by surfactants is studied by means of molecular dynamics simulations. In contrast to pure binary systems, characterized by an algebraic time dependence of the average domain size, we find that systems containing surfactants...... not fully phase separate, we observe a dynamical scaling which is independent of the surfactant concentration. The results of these simulations are in general in agreement with previous Langevin simulations [Laradji, Guo, Grant, and Zuckermann, J. Phys. A 44, L629 (1991)] and a theory of Ostwald ripening...... exhibit nonalgebraic, slow dynamics. The average domain size eventually saturates at a value inversely proportional to the surfactant concentration. We also find that phase separation in systems with different surfactant concentrations follow a crossover scaling form. Finally, although these systems do...

    11. Probabilistic cloning of equidistant states

      International Nuclear Information System (INIS)

      Jimenez, O.; Roa, Luis; Delgado, A.

      2010-01-01

      We study the probabilistic cloning of equidistant states. These states are such that the inner product between them is a complex constant or its conjugate. Thereby, it is possible to study their cloning in a simple way. In particular, we are interested in the behavior of the cloning probability as a function of the phase of the overlap among the involved states. We show that for certain families of equidistant states Duan and Guo's cloning machine leads to cloning probabilities lower than the optimal unambiguous discrimination probability of equidistant states. We propose an alternative cloning machine whose cloning probability is higher than or equal to the optimal unambiguous discrimination probability for any family of equidistant states. Both machines achieve the same probability for equidistant states whose inner product is a positive real number.

    12. Novel cloning machine with supplementary information

      International Nuclear Information System (INIS)

      Qiu Daowen

      2006-01-01

      Probabilistic cloning was first proposed by Duan and Guo. Then Pati established a novel cloning machine (NCM) for copying superposition of multiple clones simultaneously. In this paper, we deal with the novel cloning machine with supplementary information (NCMSI). For the case of cloning two states, we demonstrate that the optimal efficiency of the NCMSI in which the original party and the supplementary party can perform quantum communication equals that achieved by a two-step cloning protocol wherein classical communication is only allowed between the original and the supplementary parties. From this equivalence, it follows that NCMSI may increase the success probabilities for copying. Also, an upper bound on the unambiguous discrimination of two nonorthogonal pure product states is derived. Our investigation generalizes and completes the results in the literature

    13. Widespread avian bornavirus infection in mute swans in the Northeast United States

      Directory of Open Access Journals (Sweden)

      Payne SL

      2012-07-01

      Full Text Available Jianhua Guo,1 Lina Covaleda,1 J Jill Heatley,1 John A Baroch,2 Ian Tizard1, Susan L Payne,11Texas A&M University, College Station, TX, USA; 2USDA/APHIS Wildlife Services, Fort Collins, CO, USAAbstract: Avian bornavirus (ABV matrix (M genes were detected by RT-PCR on brain tissue obtained from 192 mute swans harvested from several Northeastern states. A RT-PCR product was detected in 45 samples. Sequencing of the PCR products confirmed the presence of ABV belonging to the ‘goose’ genotype. The prevalence of positive samples ranged from 28% in Michigan to 0% in northern New York State. Two Rhode Island isolates were cultured. Their M, N, and X-P gene sequences closely matched recently published sequences from Canada geese.Keywords: avian bornavirus, proventricular dilatation disease, reverse transcription, polymerase chain reaction, mute swans

    14. A comparative analysis of image features between weave embroidered Thangka and piles embroidered Thangka

      Science.gov (United States)

      Li, Zhenjiang; Wang, Weilan

      2018-04-01

      Thangka is a treasure of Tibetan culture. In its digital protection, most of the current research focuses on the content of Thangka images, not the fabrication process. For silk embroidered Thangka of "Guo Tang", there are two craft methods, namely, weave embroidered and piles embroidered. The local texture of weave embroidered Thangka is rough, and that of piles embroidered Thangka is more smooth. In order to distinguish these two kinds of fabrication processes from images, a effectively segmentation algorithm of color blocks is designed firstly, and the obtained color blocks contain the local texture patterns of Thangka image; Secondly, the local texture features of the color block are extracted and screened; Finally, the selected features are analyzed experimentally. The experimental analysis shows that the proposed features can well reflect the difference between methods of weave embroidered and piles embroidered.

    15. Probabilistic broadcasting of mixed states

      International Nuclear Information System (INIS)

      Li Lvjun; Li Lvzhou; Wu Lihua; Zou Xiangfu; Qiu Daowen

      2009-01-01

      It is well known that the non-broadcasting theorem proved by Barnum et al is a fundamental principle of quantum communication. As we are aware, optimal broadcasting (OB) is the only method to broadcast noncommuting mixed states approximately. In this paper, motivated by the probabilistic cloning of quantum states proposed by Duan and Guo, we propose a new way for broadcasting noncommuting mixed states-probabilistic broadcasting (PB), and we present a sufficient condition for PB of mixed states. To a certain extent, we generalize the probabilistic cloning theorem from pure states to mixed states, and in particular, we generalize the non-broadcasting theorem, since the case that commuting mixed states can be exactly broadcast can be thought of as a special instance of PB where the success ratio is 1. Moreover, we discuss probabilistic local broadcasting (PLB) of separable bipartite states

    16. Chronic restraint stress in rats causes sustained increase in urinary corticosterone excretion without affecting cerebral or systemic oxidatively generated DNA/RNA damage

      DEFF Research Database (Denmark)

      Jorgensen, Anders; Maigaard, Katrine; Wörtwein, Gitta

      2013-01-01

      acids, 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) and 8-oxo-7,8-dihydroguanosine (8-oxoGuo), respectively, in rats subjected to chronic restraint stress. To reliably collect 24h urine samples, the full 3-week restraint stress paradigm was performed in metabolism cages. We further determined frontal...... and Tnf). The metabolism cage housing in itself did not significantly influence a range of biological stress markers. In the restraint stress group, there was a sustained 2.5 fold increase in 24h corticosterone excretion from day 2 after stress initiation. However, neither whole-body nor cerebral measures......Increased oxidatively generated damage to nucleic acids (DNA/RNA) may be a common mechanism underlying accelerated aging in psychological stress states and mental disorders. In the present study, we measured the urinary excretion of corticosterone and markers of systemic oxidative stress on nucleic...

    17. Reply to comment by Konings and Plyasunov on ;First experimental determination of the solubility constant of coffinite; [Geochim. Cosmochim. Acta 181 (2016) 36-53

      Science.gov (United States)

      Szenknect, S.; Dacheux, N.; Ewing, R. C.; Navrotsky, A.

      2017-09-01

      R.J.M. Konings and A. Plyasunov investigated the values of thermodynamic data determined by Szenknect et al. (2016) from solubility experiments performed using a synthetic sample of coffinite. Especially, they focused on the value of the standard molar entropy, which was derived from these solubility data and the calorimetric measurement of the standard molar enthalpy of formation of coffinite published by Guo et al. (2015). The two independent measurements were performed on the same synthetic sample prepared by Mesbah et al. (2015) and fully characterized using complementary techniques by the two teams. We thank Konings and Plyasunov for their comment and the relevant analysis of previously published work. As they concluded, we agree that new experimental data are required to solve the ;coffinite issue;. Here, we simply wish to clarify a few points regarding the questions arising from their analysis.

    18. A janela da palavra: uma leitura de “Famigerado”, de Guimarães Rosa, à luz do conceito de limiar, de Walter Benjamin DOI - 10.5752/P.2358-3428.2012v16n31p185

      Directory of Open Access Journals (Sweden)

      Edson Santos de Oliveira

      2012-12-01

      Full Text Available Nosso objetivo é fazer uma leitura do conto "Famigerado", de Guimarães Rosa, a partir do conceito de limiar, conforme Walter Benjamin. Pretendemos articular esse conceito com uma das categorias estéticas mais estudadas na obra de Guimarães Rosa: a ambiguidade. Assim, o espaço de transição em que se dá a narrativa se integra ao corpo ambíguo da linguagem, possibilitando não só a emergência de chistes por parte do jagunço Damásio, como também propiciando ao personagem-narrador uma oportunidade de se equilibrar no limiar da significação. Se o conceito de limiar em Benjamin permite um pensamento por imagem, processo semelhante ocorre na escrita rosiana.  Palavras-chave: Limiar. Ambiguidade escrita. Imagem.

    19. Mobilization and Resistance through Social Media

      DEFF Research Database (Denmark)

      Vestergaard Jørgensen, Anne; Etter, Michael; Colleoni, Elanor

      Social media are widely considered as driving force for the institutionalization of CSR. It holds great potential for the empowerment of citizens, consumers, social movements or pressure groups. So far, this role of social media in the strategic communication of pressure groups is underexplored...... and associative frames (Guo & McCombs, 2011, Schultz et al., 2011) of the actors via semantic network analysis (1765 sentences in social media, 132 in press releases). The findings allow further evaluations of institutional, ethical and political conditions and reflections on the implications of “social media....... By analysing the use and content of social media of protest actors on the one hand and corporations on the other, the paper contributes to understanding the mechanisms, conditions and effects of social media based pressure on corporations. Drawing on social movement theory, discourse theory and neo...

    20. Gas-liquid Relative Permeability Estimation in 2D Porous Media by Lattice Boltzmann Method: Low Viscosity Ratio 2D LBM Relative Permeability

      Directory of Open Access Journals (Sweden)

      Sadegh Mahmoudi

      2013-04-01

      Full Text Available This work is a primary achievement in studying the CO2 and N2–oil systems. To predict gas-liquid relative permeability curves, a Shan-Chen type multicomponent multiphase lattice Boltzmann model for two-phase flow through 2D porous media is developed. Periodic and bounce back boundary conditions are applied to the model with the Guo scheme for the external body force (i.e., the pressure gradient. The influence of relationship between cohesion and adsorption parameters and the interfacial tension values in Young's equation, pore structure (micro scan image derived porous media response is compared with corresponding porosity and permeability ideal sphere pack structure, and saturation distribution on relative permeability curves are studied with the aim to achieve the realistic stable condition for the simulation of gas-liquid systems with a low viscosity ratio.

    1. Rancang Bangun Graphical User Interface Untuk Pergerakan Motor Servo menggunakan Microsoft Visual Basic 2010 Express

      Directory of Open Access Journals (Sweden)

      Anggoro S Pramudyo

      2016-03-01

      Full Text Available Zaman sekarang ini teknologi sedang berkembang pesat dan robot-robot dirancang untuk dapat membantu pekerjaan dan tugas-tugas manusia. Motor servo merupakan salah satu jenis dari motor DC dan banyak diaplikasikan pada dunia robotik maupun peralatan lain, contohnya motor servo yang digunakan untuk robot berkaki. Dalam penggunaannya motor servo dapat bergerak karena ada sinyal yang dibangkitkan melalui sinyal PWM. Sinyal yang dihasilkan akan membentuk sudut sesuai nilai yang diberikan. Penelitian ini bertujuan untuk membuat perangkat lunak GUI untuk membuat pergerakan motor servo menggunakan Microsoft Visual Basic dengan bantuan database menggunakan Microsoft Access. Pergerakan motor servo dapat bergerak secara sekuen dan real time menggunakan GUI yang dihubungkan dengan Arduino mega 2560. Parameter yang terdapat di dalam database juga bisa langsung di-export menjadi file Arduino. Hasil penelitian ini GUI yang telah dibuat dapat menggerakkan motor servo secara lancar melalui komunikasi serial ketika baudrate diatur pada kecepatan 9600 bps. GUI yang dibuat juga menghasilkan sudut untuk motor servo yaitu dari 00 sampai 1800 secara tepat dan akurat, sehingga mempercepat waktu dalam  menentukan sudut untuk pergerakan motor servo yang akan digunakan.

    2. YAPAY DENİZ SUYUNDA FARKLI HIZLARDA Cu-%10 Ni ALAŞIMININ EROZYON-KOROZYON DAVRANIŞI

      Directory of Open Access Journals (Sweden)

      Mehmet GAVGALI

      2002-02-01

      Full Text Available Bu çalışmada yapay deniz suyunda Cu-10 % Ni bakır-nikel alaşımının erozyon-korozyon davranışı incelenmiştir. Erozyon-korozyon testleri farklı hızlarda dönen silindirik elektrot kullanılarak gerçekleştirilmiştir. Denemelerde serbest korozyon potansiyeli, anodik polarizasyon, elektrokimyasal impedans analizi, ağırlık kaybı testleri ve optik mikroskop incelemesi yapılmıştır. Dönme hızı ve zamanın artması ile yapay deniz suyundaki Cu-10 % Ni alaşımının korozyon hızı artmıştır. Koruyucu yüzey filmindeki hasarın, dönme hızı 1600 d/d olduğunda 3. saatten itibaren, 2000 d/d olduğunda ise 1. saatten itibaren başladığı ve giderek arttığı belirlenmiştir.

    3. Constructing the “Arab Spring”: News Discourses in Turkish Newspapers

      Directory of Open Access Journals (Sweden)

      Banu Dağtaş

      2013-12-01

      Full Text Available Originating in Tunisia and spreading rapidly to Egypt, Yemen, Bahrain, and Libya, the recent wave of popular movements that the Western media have dubbed the “Arab Spring” has been closely monitored by the whole world including in Turkey. This country is geographically close to the region and the ruling Justice and Development Party (AKP has been active in developing foreign policies in relation to the key countries involved. This paper analyzes the news discourses in the reports published between January 25th and February 25th, 2011, in six Turkish national newspapers. This is the period when upheaval reached its peak in Tahrir Square in Cairo, the most potent symbol of “Arab Spring”. The newspapers sampled fall into two categories, those supporting the AKP government (Star, Zaman, and Sabah and those not supporting the AKP government (Cumhuriyet, Hürriyet, and Taraf. To map the discursive fields employed in the news reports, this paper draws on methods from critical discourse analysis and examines news actors and their quotation patterns, lexicalization, overlexicalization and syntactic preferences.

    4. Did opening of the South China Sea impact development of the Asian Monsoon? Results from Oligocene microfossils, IODP Site U1435, northern South China Sea

      Science.gov (United States)

      Kulhanek, Denise K.; Su, Xin; Li, Qianyu; Gregory, Mitch; Warny, Sophie; Clift, Peter D.

      2016-04-01

      Development of the Asian Monsoon is linked to uplift of the Himalayas and Tibetan Plateau in the Cenozoic, with good evidence for a strong monsoon system by the late Oligocene to early Miocene (e.g., Guo et al., 2002; Clift et al., 2008). However, Licht et al. (2014) suggested the presence of an Asian Monsoon in the late Eocene. Recent scientific ocean drilling in the Indian Ocean and surrounding marginal seas gives us the opportunity to test this hypothesis with newly recovered Paleogene sediment cores. International Ocean Discovery Program Expedition 349 to the South China Sea recovered a 30 m section of primarily lower Oligocene nannofossil-rich claystone at Site U1435, located near the northern continent/ocean boundary. A thick sandstone unit devoid of typical marine microfossils underlies the marine claystone. The sandstone is interpreted as a deltaic or restricted marine deposit and is dated to the Eocene based on the presence of organic-walled palynomorphs, suggesting that a hiatus of several million years likely separates the sandstone below from the Oligocene marine claystone. This hiatus is interpreted as the breakup unconformity, with paleodepths in the South China Sea increasing during the Oligocene. Thus, this claystone should record if opening of the South China Sea during the early Oligocene influenced development of the Asian Monsoon. Combined calcareous nannofossil and planktonic foraminifer biostratigraphy indicates that the 30 m section is primarily early Oligocene in age (~33.5-30 Ma) and was deposited on the middle slope, with paleodepths >500 m. Stable oxygen isotopes from planktonic foraminifers become heavier up-hole, suggestive of cooling/deepening in the region, whereas carbon isotopes record variable conditions with no distinct maxima or minima. Calcareous nannoplankton primarily live in the upper 50 m of the ocean and are sensitive to sea-surface temperature and nutrient conditions, thus making them useful recorders of paleoceanographic

    5. Prognostic significance of thymidylate synthase in postoperative non-small cell lung cancer patients

      Directory of Open Access Journals (Sweden)

      Zhao HY

      2014-07-01

      Full Text Available Hong-Yun Zhao,1,* Guo-Wei Ma,1,* Ben-Yan Zou,1,* Mei Li,1 Su-Xia Lin,1 Li-Ping Zhao,2 Ying Guo,1 Yan Huang,1 Ying Tian,1 Dan Xie,1 Li Zhang1 1Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People’s Republic of China; 2Department of Medical Oncology, Zhongshan Hospital of Sun Yat-Sen University, Zhongshan People’s City Hospital, Zhongshan, People’s Republic of China *The first three authors contributed equally to this work Abstract: The aim of the present study was to investigate the clinicopathologic/prognostic significance of thymidylate synthase (TS, orotate phosphoribosyltransferase (OPRT, and thymidine phosphorylase (TP proteins in postoperative non-small cell lung cancer (NSCLC patients. Microarray slides from a set of 178 NSCLC patients were used for the detection of TS, OPRT, and TP expression by immunohistochemistry. The correlation between clinicopathologic factors and protein expression of three proteins was analyzed. Ninety seven carcinomas (57.4% were TS-positive, 90 carcinomas (53.9% were OPRT-positive, and 102 carcinomas (69.4% were TP-positive. Compared with the TS-positive patients, the overall survival (OS was significantly lower in the TS-negative patients (hazard ratio [HR] =1.766, 95% confidence interval [CI] =1.212–2.573, P=0.003. Significant differences between TS-positive and TS-negative patients was also observed in the following stratified analyses: 1 adenocarcinoma subgroup (HR =2.079, 95% CI =1.235–3.500, P=0.006; 2 less than 60-year-old subgroup (HR =1.890, 95% CI =1.061–3.366, P=0.031; 3 stage II/III subgroup (HR =1.594, 95% CI =1.036–2.453, P=0.034; and 4 surgery plus adjuvant therapy subgroup (HR =1.976, 95% CI =1.226–3.185, P=0.005. However, the OS was not significantly correlated with OPRT or TP protein expression. This study demonstrates that the TS level in tumor tissues may be a useful marker

    6. Calculation of the permeability in porous media using the lattice Boltzmann method

      International Nuclear Information System (INIS)

      Eshghinejadfard, Amir; Daróczy, László; Janiga, Gábor; Thévenin, Dominique

      2016-01-01

      Highlights: • Lattice Boltzmann simulation of fluid flow in porous media delivers a high accuracy. • Domain size, relaxation time and force scheme affect the calculated permeability. • Multiple relaxation time model shows very low viscosity dependence as compared to single relaxation time. • The choice of relaxation time and force scheme is a trade-off between the required accuracy and computational cost. - Abstract: In this paper, the lattice Boltzmann method (LBM) is used to simulate three-dimensional laminar flows in porous media and to calculate the associated permeability. An in-house, parallelized code using the message passing interface technique is employed for the study. Three different flow configurations are studied: first, by manually specifying solid cells in a face-centered cube (FCC); then, doing the same in a body-centered cube (BCC); and finally by reading the solid cells for a real 3D geometry from a set of experimental 2D computed tomography images. In all simulations, the Reynolds number is kept well below 1. It was found that the current LBM simulations yield good estimates for the permeability value. The impact of the employed force scheme and single- or multiple-relaxation time (SRT, MRT) was also studied. Although each force scheme (Guo-SRT, Guo-MRT and Shan-Chen-SRT) may show better results in some regions, the strong dependency of SRT models on relaxation time suggests that the proper choice of the force scheme, relaxation time and domain resolution is a compromise between the required accuracy and computational cost. First, higher resolutions lead as expected to increasingly accurate results but requires more computational cost and time. Second, the MRT model shows a lower viscosity dependence in comparison with SRT models but is somewhat slower. Also, the results are more sensitive to the relaxation time value for coarser domains. Furthermore, lower relaxation times necessitate a higher number of iterations to reach the steady

    7. Efficacy and safety of ifosfamide-based chemotherapy for osteosarcoma: a meta-analysis

      Directory of Open Access Journals (Sweden)

      Fan XL

      2015-11-01

      Full Text Available Xiao-Liang Fan,1,* Guo-Ping Cai,2,* Liu-Long Zhu,1 Guo-Ming Ding1 1Department of Orthopaedics, Hangzhou First People’s Hospital, Nanjing Medical University, Hangzhou, 2Department of Orthopaedics, Jinshan Hospital, Fudan University, Shanghai, People’s Republic of China *These authors contributed equally to this work Background: The efficacy of ifosfamide-based chemotherapy in the treatment of osteosarcoma has been investigated; however, results are inconsistent. Therefore, we reviewed the relevant studies and conducted a meta-analysis to assess the efficacy of ifosfamide-based chemotherapy in patients with osteosarcoma.Methods: A systematic literature search on PubMed, Embase, and Web of Science databases was performed. Eligible studies were clinical trials of patients with osteosarcoma who received ifosfamide-based chemotherapy. Hazard ratios (HRs were pooled to compare event-free survival (EFS and overall survival (OS. Risk ratios (RRs were pooled to compare good histologic response rates and adverse event incidence. Meta-analysis was performed using a fixed-effects model or a random-effects model according to heterogeneity.Results: A total of seven randomized controlled trials were included in this meta-analysis. Pooled results showed that ifosfamide-based chemotherapy significantly improved EFS (HR=0.72, 95% confidence interval [CI]: 0.63, 0.82; P=0.000 and OS (HR=0.83, 95% CI: 0.70, 0.99; P=0.034; furthermore, this form of chemotherapy increased good histologic response rate (RR=1.27, 95% CI: 1.10, 1.46; P=0.001. In addition, patients in the ifosfamide group exhibited a significantly higher incidence of fever (RR=2.23, 95% CI: 1.42, 3.50; P=0.000 and required more frequent platelet transfusion (RR=1.92, 95% CI: 1.23, 3.01; P=0.004.Conclusion: This meta-analysis confirmed that ifosfamide-based chemotherapy can significantly improve EFS and OS; this chemotherapy can also increase good histologic response rate in patients with osteosarcoma

    8. Present mantle flow in North China Craton constrained by seismic anisotropy and numerical modelling

      Science.gov (United States)

      Qu, W.; Guo, Z.; Zhang, H.; Chen, Y. J.

      2017-12-01

      North China Carton (NCC) has undergone complicated geodynamic processes during the Cenozoic, including the westward subduction of the Pacific plate to its east and the collision of the India-Eurasia plates to its southwest. Shear wave splitting measurements in NCC reveal distinct seismic anisotropy patterns at different tectonic blocks, that is, the predominantly NW-SE trending alignment of fast directions in the western NCC and eastern NCC, weak anisotropy within the Ordos block, and N-S fast polarization beneath the Trans-North China Orogen (TNCO). To better understand the origin of seismic anisotropy from SKS splitting in NCC, we obtain a high-resolution dynamic model that absorbs multi-geophysical observations and state-of-the-art numerical methods. We calculate the mantle flow using a most updated version of software ASPECT (Kronbichler et al., 2012) with high-resolution temperature and density structures from a recent 3-D thermal-chemical model by Guo et al. (2016). The thermal-chemical model is obtained by multi-observable probabilistic inversion using high-quality surface wave measurements, potential fields, topography, and surface heat flow (Guo et al., 2016). The viscosity is then estimated by combining the dislocation creep, diffusion creep, and plasticity, which is depended on temperature, pressure, and chemical composition. Then we calculate the seismic anisotropy from the shear deformation of mantle flow by DREX, and predict the fast direction and delay time of SKS splitting. We find that when complex boundary conditions are applied, including the far field effects of the deep subduction of Pacific plate and eastward escaping of Tibetan Plateau, our model can successfully predict the observed shear wave splitting patterns. Our model indicates that seismic anisotropy revealed by SKS is primarily resulting from the LPO of olivine due to the shear deformation from asthenospheric flow. We suggest that two branches of mantle flow may contribute to the

    9. APHORISMS IN THE NOVELS OF HAKAN GÜNDAY HAKAN GÜNDAY ROMANLARINDA AFORİZMALAR

      Directory of Open Access Journals (Sweden)

      Caner KERİMOĞLU

      2010-01-01

      Full Text Available In this article, aphorisms in the novels of Hakan Günday are studied. Initially, in introduction some information about the etymology of the word “aphorism”, the place of aphorisms in Turkish literature, Hakan Günday and Günday’s novels is given, and then aphorisms in the novels are listed. Aphorisms are listed according to thematic titles. 8 titles are identified as human, time, place, business, religion-nation, organization, communication and other concepts. Distribution of aphorisms is as follows : Human 55, time 30, place 5, business 24, organization 15, religion-nation 12, communication 9, other concepts 23. This article includes 173 aphorisms in Günday’s novels. Bu makalede Hakan Günday’ın romanlarındaki aforizmalar incelenmiştir. İlk olarak giriş bölümünde aforizma kelimesinin kökeni, Türk edebiyatında aforizma türünün yeri, Hakan Günday ve Günday’ın romanları hakkında kısa bilgiler verilmiştir. Ardından inceleme bölümünde romanlardaki aforizmalar sınıflandırılmıştır. Aforizmalar tematik başlıklara göre sıralanmıştır. İnsan, zaman, mekân, iş, örgütlenme, din-ulus, iletişim ve diğer kavramlar olmak üzere 8 başlık belirlenmiş ve aforizmalar bu 8 başlığa göre listelenmiştir. İnceleme sonucunda aforizmaların bu başlıklara dağılımı şu şekilde olmuştur: İnsan başlığı altında 55, zaman başlığı altında 30, mekân başlığı altında 5, iş başlığı altında 24, örgütlenme başlığı altında 15, din-ulus başlığı altında 12, iletişim başlığı altında 9, diğer kavramlar başlığı altında 23. Çalışmada Hakan Günday’ın romanlarında geçen toplam 173 aforizmaya yer verilmiştir

    10. INTEGRASI MATEMATIKA DAN ISLAM DALAM PEMBELAJARAN MATEMATIKA

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      Samsul Maarif

      2015-07-01

      Full Text Available ABSTRAK Pembelajaran matematika harus mengalami perubahan dalam konteks perbaikan mutu pendidikan sehingga dapat meningkatkan hasil pembelajaran yang optimal. Oleh karena itu, upaya terus dilakukan untuk terwujudnya suatu pembelajaran yang inovatif sesuai dengan perkembangan zaman dan tekhnologi. Disamping pendidikan diselaraskan dengan kemajuan teknologi, pendidikan juga diharapkan dapat membangun nilai dan watak dari setiap peserta didik melalui nilai-nilai agama.Al-Quaran merupakan kitab suci umat islam yang merupakan sumber dari segala sumber ilmu. Keagungannya tidak akan tertandingi dan tak jua lekang oleh zaman. Oleh karenaya kita sebagai umat muslim patut dan menjadi keharusan menjadikan Al-Quran sebagai rujukan utama untuk pengembangan ilmu sebelum merujuk kepada teori ataupun konsep-konsep lainnnya. Pandangan seperti tersebut tidaklah salah karena Al-Quran sangat berpengaruh pada pengembangan bidang ilmu. Hal tersebut terlihat jelas adanya penghargaan yang teramat tinggibagi mereka yang beriman dan berilmu dibandingkan dengan orang yang biasa-biasa saja.Hal tersebut menunjukan Al-Quran sangat konsen dalam perkembangan ilmu pengetahuan. Oleh sebab itu, perlu kiranya dunia pendidikan tidak terkecuali dalam pembelajaran matematika mengintegrasikan nilai-nilai yang terkandung dalam agama islam dalam setiap pembelajaran. Sehingga, selain dapat mempelajari matematika siswa juga dapat mempelajari keagungan Alloh melalui pendekatan materi-materi matematika. Kata Kunci    :   Islam, Matematika, Pembelajaran Matematika   ABSTRACT Learning mathematics should be amended in the context of improvement of the quality of education so as to enhance the optimal learning outcomes. Therefore, efforts continue to be made to the realization of an innovative learning in accordance with the times and technology. Besides education aligned with technological advances, education is also expected to build the value and character of each learner through the

    11. Das amarras do poder às entrelinhas do discurso: a pedagogia ambígua da favela em Capão Pecado, de Ferréz

      Directory of Open Access Journals (Sweden)

      Juan Filipe Stacul

      2016-12-01

      Full Text Available Pretende-se, no presente trabalho, investigar como o narrador de Capão Pecado propõe um contraponto ao código de moral da marginalidade, assumindo um tom pedagógico ambíguo que, ao mesmo tempo, critica o “sistema” e valoriza as regras de moralidade por este pregoadas. Para tal análise, pretende-se relacionar a instância narrativa da obra em questão com os pressupostos teóricos de Michel Foucault sobre a dissolução das relações de poder, representada pela figura do panóptico. Verifica-se, com isso, que os valores morais da sociedade tradicional burguesa dissolvem-se nas mais diversas estruturas, diluindo, nesse processo, algumas fronteiras entre centro e margem para se estabelecer como norma até mesmo onde são questionados e subvertidos.

    12. A heuristic approach to handle capacitated facility location problem evaluated using clustering internal evaluation

      Science.gov (United States)

      Sutanto, G. R.; Kim, S.; Kim, D.; Sutanto, H.

      2018-03-01

      One of the problems in dealing with capacitated facility location problem (CFLP) is occurred because of the difference between the capacity numbers of facilities and the number of customers that needs to be served. A facility with small capacity may result in uncovered customers. These customers need to be re-allocated to another facility that still has available capacity. Therefore, an approach is proposed to handle CFLP by using k-means clustering algorithm to handle customers’ allocation. And then, if customers’ re-allocation is needed, is decided by the overall average distance between customers and the facilities. This new approach is benchmarked to the existing approach by Liao and Guo which also use k-means clustering algorithm as a base idea to decide the facilities location and customers’ allocation. Both of these approaches are benchmarked by using three clustering evaluation methods with connectedness, compactness, and separations factors.

    13. Mathematical methods for hydrodynamic limits

      CERN Document Server

      Masi, Anna

      1991-01-01

      Entropy inequalities, correlation functions, couplings between stochastic processes are powerful techniques which have been extensively used to give arigorous foundation to the theory of complex, many component systems and to its many applications in a variety of fields as physics, biology, population dynamics, economics, ... The purpose of the book is to make theseand other mathematical methods accessible to readers with a limited background in probability and physics by examining in detail a few models where the techniques emerge clearly, while extra difficulties arekept to a minimum. Lanford's method and its extension to the hierarchy of equations for the truncated correlation functions, the v-functions, are presented and applied to prove the validity of macroscopic equations forstochastic particle systems which are perturbations of the independent and of the symmetric simple exclusion processes. Entropy inequalities are discussed in the frame of the Guo-Papanicolaou-Varadhan technique and of theKipnis-Oll...

    14. Türkiye'de Enflasyon - Büyüme İlişkisi : Zaman Serisi Analizi = Inflation - Growth Relationship in Turkey : Time Series Analysis

      Directory of Open Access Journals (Sweden)

      Orhan KARACA

      2003-06-01

      Full Text Available The relationship between inflation and growth in Turkey is examined in this paper with time series analysis using quarterly data related to 1987-2002 period. A unidirectional casuality runs from inflation to growth within the Granger casuality analysis. The regression analysis we have made points out that inflation effects growth negatively. Every 1 point increase in inflation is found to decrease growth rate by 0.37 points during the examined period.

    15. Okuma Yazma Öğretimi Yöntemleri Ve “Ses Temelli Cümle Yöntemi” Uygulaması The Methods Of Teaching Reading And Writing In Turkish: Practice The Phonetic Based Method

      Directory of Open Access Journals (Sweden)

      Raşit KOÇ

      2012-12-01

      ğrenmede ve bu işi zevkli bir alışkanlığa dönüştürmede okuma ve yazma öğretiminde nasıl bir yol izleneceği de önem kazanmaktadır.Ülkemizde dünyadaki gelişmelere paralel olarak okuma yazma öğretiminde kullanılan yöntemler de zaman içerisinde değişmiştir. Okuma yazma öğretiminde uzun süre harf yöntemi kullanılmıştır. Harf yöntemini sırasıyla ses yöntemi, hece yöntemi kelime ve cümle yöntemi izlemiştir.Davranışçı kuram merkeze alınarak hazırlanmış olan eski Türkçe programı öğrencileri ezbere sevk ettiği, etkili ve kalıcı bir okuma alışkanlığı kazandırmada yeterli olmadığı için eleştirilere muhatap olmuştur. Zaman zaman revizyon geçiren eski program 2005 yılında yerini yeni programa bırakmıştır.Temel felsefesini yapılandırmacı yaklaşımın oluşturduğu yeni Türkçe programında okuma yazma öğretim yöntemi olarak ses temelli cümle yöntemi benimsenmiştir. Bu yöntemle beraber dik temel harflerle yapılan yazı öğretimi yerine bitişik eğik yazı kullanılmaya başlanmıştır.Bu çalışmada, okuma yazma öğretiminde günümüze kadar kullanılan yöntemler ve bu yöntemlerin faydalı ve sakıncalı yönleri belirtildikten sonra yeni hazırlanan Türkçe programında yer alan ses temelli cümle yöntemiyle ilgili düşüncelere yer verilecektir.

    16. ÖRGÜTLERDE ESNEK ÇALIŞMA UYGULAMALARI VE BUNA İLİŞKİN OLARAK 4857 SAYILI İŞ KANUNUNDA GETİRİLEN DÜZENLEMELERİN İNCELENMESİ

      OpenAIRE

      BOLAT, Tamer; AYTEMİZ SEYMEN, Oya; BOLAT, Oya İnci

      2006-01-01

      Son yıllarda geleneksel çalışma düzeninden farklı olarak, örgütlerde, sözleşmeler, görevler, çalışma zamanı, çalışma süresi ve mekânı açısından esnek uygulamalarla yaygın bir şekilde karşılaşılmaktadır. Bu kapsamda, esnek çalışma saatleri, kısmî süreli çalışma, iş paylaşımı, sıkıştırılmış iş haftası, vardiyalı çalışma ve uzaktan çalışma gibi uygulamalar en çok karşılaşılan esnek çalışma türleridir. Sözü edilen uygulamalardan kısmî süreli çalışma, çağrı üzerine çalışma, geçici iş ilişkisi ve s...

    17. EKSISTENSI BAHASA INDONESIA SEBAGAI BAHASA PERSATUAN

      Directory of Open Access Journals (Sweden)

      Marsudi Marsudi

      2008-11-01

      Full Text Available Bahasa Indonesia lahir dari Bahasa Melayu yang pada zaman dulu menjadi bahasa lingua franca, yakni bagasa perdagangan antarpulau di nusantara. Kemudian dikukuhkan menjadi bahasa persatuan melalui momen Sumpah Pemuda. Bahasa Melayu menjadi dominan di kala itu dikarenakan fleksibelitasnya akan bahasa-bahasa lain. Dengan fakta tersebut, tepatnya 28 Oktober 1928, bahasa Melayu diangkat sebagai bahasa persatuan dan tahun 1945 diresmikan sebagai bahasa negara. Permasalahan yang muncul dalam eksistensi bahasa Indonesia adalah bagaimanakah cara mempertahankan eksistensi bahasa Indonesia? Tidak hanya masalah eksistensi saja, tetapi sanggupkah bahasa-bahasa daerah di negeri ini memperkaya kosa kata dan istilah bahasa Indonesia? Selain itu, bagaimanakah potensi bahasa Indonesia di era globalisasi? Eksistensi bahasa Indonesia, selain dipengaruhi kekonsistenan penggunaanya, juga didukung oleh kemampuan bahasa tersebut dalam mengungkapkan fenomena baru yang berkembang. Oleh karena itu, perkembangan bahasa Indonesia sangat tergantung pada tingkat keberhasilan menciptakan kosa kata dan istilah-istilah baru. Bahasa Indonesia sudah mulai mengglobal karena bahasa Indonesia memiliki sifat terbuka dan demokratis. Perkembangan yang terjadi sekarang dan yang datang tidak hanya menyangkut masalah struktur dan bahasa, tetapi lebih jauh mengungkapkan permasalahan manusia baru yang dialami manusia di dalam sebuah proses perubahan dalam berbagai aspek kehidupan

    18. PENERAPAN KABA MINANGKABAU SEBAGAI MEDIA PELESTARIAN BAHASA AMAI (IBU DAN KESUSASTRAAN DALAM PENDIDIKAN LITERASI DI MINANGKABAU

      Directory of Open Access Journals (Sweden)

      Wahyudi Rahmat

      2016-11-01

      Full Text Available Penelitian ini mencoba menerapkan Kaba Minangkabau sebagai media pemertahanan bahasa ibu, kesusastraan dan pengajaran dalam keluarga di Minangkabau. Pengajaran ini bermakna bahwa dengan terus mempertahankan eksistensi Kaba dalam masyarakat, maka secara otomatis pelestarian bahasa ibu juga akan terus bertahan dalam perkembangan zaman. Bahasa amai atau ibu yang ada dalam kaba Minangkabau jika terus dipertahankan sebagai sebuah inovasi akan menjadikannya sebuah bahasa yang lebih mulia. Sehingga dapat dikatakan bahwa bahasa daerah  atau bahasa Minangkabau adalah sebuah bentuk kekayaan budaya yang dapat dimanfaatkan, bukan hanya sebagai sebuah kepentingan pengembangan  melainkan sebagai sebuah eksistensi bahasa itu sendiri. Penerapan Kaba Minangkabau  sebagai media pelestarian bahasa ibu ini sudah lama diterapkan pada proses belajar dan mengajar di program studi Sastra Daerah Universitas Andalas Sumatera Barat. Hasil penelitian ini menunjukkan sebagian besar mahasiswa Sastra Daerah menggunakan bahasa Minangkabau dalam berkomunikasi dan dalam situasi komunikasi ini mahasiswa Sastra Daerah mampu mengembangkan pengalaman empiris untuk pengembangan kearifan hidup dalam kaba baik secara individual maupun secara kolektif di kampus ataupun di masyarakat. Secara tidak langsung juga bahasa amai atau ibu yang ada dalam kaba Minangkabau dapat terus dipertahankan sebagai sebuah inovasi akan menjadikannya sebuah bahasa yang lebih mulia.

    19. Peranan Teknologi dalam Mendukung Proses Berpikir Level C3 Siswa pada Materi Operasi Himpunan melalui Penggunaan Swish Max4

      Directory of Open Access Journals (Sweden)

      Arinaldi Arinaldi

      2018-03-01

      Full Text Available Perkembangan teknologi pada abad ke-21 ini sudah sangat pesat, membuat guru menjadi lebih kreatif dalam hal membuat media pembelajaran yang inovatif, menarik, serta tidak ketinggalan zaman. Dengan menggunakan media visual guru dapat memberikan visual tertentu pada siswa dalam proses pembelajaran, yang nantinya diharapkan dapat membantu siswa dalam berpikir C3. Lalu dilatar belakangi oleh kemampuan siswa yang rendah dalam mengerjakan soal applikasi operasi pada himpunan dikehidupan sehari-hari sekaligus memvisualisasikan operasi himpunan, berdasarkan survei peneliti melalui wawancara dengan guru SMP Negeri 11 Tanjungpinang. Sehingga pada penelitian ini peneliti menggunakan media visual berbasis multimedia berbantuan software swish max4, untuk membantu siswa berpikir hingga level C3 atau pada ranah mengaplikasikan khususnya pada materi operasi himpunan dan juga dapat memvisualisasikan operasi himpunan dikehidupan sehari-hari. Telah dilakukan eksperimen di kelas VII.1 dan kelas VII.2 pada SMP Negeri 11 Tanjungpinang, memperoleh hasil posttest kelas eksperimen lebih tinggi 76,24 dibangdingkan dengan kelas kontrol 66,92, terbukti bahwa kelas yang diberikan treatment media swish max4  dapat membantu siswa dalam berpikir hingga level C3 atau mengapplikasikan. Kata kunci : Swish max4, berpikir level C3, Soal applikasi operasi himpunan

    20. An algorithm for preferential selection of spectroscopic targets in LEGUE

      International Nuclear Information System (INIS)

      Carlin, Jeffrey L.; Newberg, Heidi Jo; Lépine, Sébastien; Deng Licai; Chen Yuqin; Fu Xiaoting; Gao Shuang; Li Jing; Liu Chao; Beers, Timothy C.; Christlieb, Norbert; Grillmair, Carl J.; Guhathakurta, Puragra; Han Zhanwen; Hou Jinliang; Lee, Hsu-Tai; Liu Xiaowei; Pan Kaike; Sellwood, J. A.; Wang Hongchi

      2012-01-01

      We describe a general target selection algorithm that is applicable to any survey in which the number of available candidates is much larger than the number of objects to be observed. This routine aims to achieve a balance between a smoothly-varying, well-understood selection function and the desire to preferentially select certain types of targets. Some target-selection examples are shown that illustrate different possibilities of emphasis functions. Although it is generally applicable, the algorithm was developed specifically for the LAMOST Experiment for Galactic Understanding and Exploration (LEGUE) survey that will be carried out using the Chinese Guo Shou Jing Telescope. In particular, this algorithm was designed for the portion of LEGUE targeting the Galactic halo, in which we attempt to balance a variety of science goals that require stars at fainter magnitudes than can be completely sampled by LAMOST. This algorithm has been implemented for the halo portion of the LAMOST pilot survey, which began in October 2011.

    1. Recent development in clusters of rare earths and actinides. Chemistry and materials

      Energy Technology Data Exchange (ETDEWEB)

      Zheng, Zhiping (ed.) [Arizona Univ., Tucson, AZ (United States). Dept. of Chemistry and Biochemistry

      2017-02-01

      This book contains the following eight contributions: 1. Lanthanide Hydroxide Cluster Complexes via Ligand-Controlled Hydrolysis of the Lanthanide Ions (Zhonghao Zhang, Yanan Zhang, and Zhiping Zheng); 2. Synthesis and Structures of Lanthanide-Transition Metal Clusters (Xiu-Ying Zheng, Xiang-Jian Kong, and La-Sheng Long); 3. Hydrothermal Synthesis of Lanthanide and Lanthanide-Transition-Metal Cluster Organic Frameworks via Synergistic Coordination Strategy (Jian-Wen Cheng and Guo-Yu Yang); 4. Oxo Clusters of 5f Elements (Sarah Hickam and Peter C.); 5. Construction and Luminescence Properties of 4f and d-4f Clusters with Salen-Type Schiff Base Ligands (Xiaoping Yang, Shiqing Wang, Chengri Wang, Shaoming Huang, and Richard A.); 6. 4f-Clusters for Cryogenic Magnetic Cooling (Yan-Cong Chen, Jun-Liang Liu, and Ming-Liang Tong); 7. Lanthanide Clusters Toward Single-Molecule Magnets (Tian Han, You-Song Ding, and Yan-Zhen Zheng); 8. Molecular Rare Earth Hydride Clusters (Takanori Shima and Zhaomin Hou).

    2. Female Gynecologists and Their Birth Control Clinics: Eugenics in Practice in 1920s-1930s China.

      Science.gov (United States)

      David, Mirela

      2018-01-01

      Yang Chao Buwei, the first Chinese translator of Margaret Sanger's What Every Girl Should Know, was the first female gynecologist to open up a birth control clinic in China. By the 1930s, other female gynecologists, like Guo Taihua, had internalized and combined national and eugenic concerns of race regeneration to focus on the control of women's reproduction. This symbiosis between racial regeneration and birth control is best seen in Yang Chongrui's integration of birth control into her national hygiene program. This article traces the efforts of pioneer gynecologists in giving contraceptive advice at their birth control clinics, which they framed as a humanitarian effort to ease the reproductive burden of working-class women. It also examines their connections with Sanger's international birth control movement, and their advocacy of contraception as practitioners, translators, and educators. The author argues that these Chinese female gynecologists not only borrowed, but adapted, Western scientific knowledge to Chinese social conditions through their writings and translations and in their clinical work.

    3. Aripiprazole-associated tic in a schizophrenia patient

      Directory of Open Access Journals (Sweden)

      Guo X

      2015-03-01

      Full Text Available Xieli Guo,1,2,* Dali Lu,3,* Yugang Jiang1 1Department of Neurosurgery, Second Xiangya Hospital of Central South University, Changsha, Hunan, People’s Republic of China; 2Department of Neurosurgery, Jinjiang Hospital of Quanzhou Medical College, Jinjiang, Fujian, People’s Republic of China; 3Department of Psychiatry, Xiamen Xianyue Hospital, Xiamen, Fujian, People’s Republic of China *These authors contributed equally to this work Abstract: Tic disorder, characterized by the presence of both motor and vocal tics is common in adolescents and adults. Antipsychotics including typical antipsychotics and atypical antipsychotics are generally recognized by experts as the most effective pharmacological treatment for tics. However, previous studies suggest that tic-like symptoms might manifest during treatment with atypical antipsychotics such as clo­zapine, quetiapine, but not aripiprazole. We present the first case, to our knowledge, of an adult schizophrenia patient who developed tics during treatment with aripiprazole. Keywords: aripiprazole, antipsychotics, tic, schizophrenia, side effect

    4. Introduction to the thematic series "Coupling of the magnetosphere-ionosphere system"

      Science.gov (United States)

      Yao, Z. H.; Murphy, K. R.; Rae, I. J.; Balan, N.

      2017-12-01

      This thematic series contains 4 papers mostly presented at the 2016 AOGS meeting in Beijing. The four papers investigate four key regions in the magnetosphere-ionosphere coupling process: mid-tail magnetosphere, near-Earth magnetosphere, inner magnetosphere, and the polar ground region. Guo et al. (Geosci Lett 4:18, 2017) study the current system in reconnection region using 2.5D particle-in-cell simulations. Yao et al. (Geosci Lett 4:8, 2017) use conjugate measurements from ground auroral imagers and in situ THEMIS spacecraft to reveal the mechanism for the wave-like auroral structures prior to substorm onset. Zhang et al. (Geosci Lett 4:20, 2017) investigate the profiles of resonance zone and resonant frequency in the Landau resonance between radiation belt electrons and magnetosonic waves and between protons and cyclotron waves. Rae et al. (Geosci Lett 4:23, 2017) determine the relative timing between sudden increases in amplitude, or onsets, of different ultra-low-frequency wave bands during substorms.

    5. Effects of density and force discretizations on spurious velocities in lattice Boltzmann equation for two-phase flows

      KAUST Repository

      Xiong, Yuan

      2014-04-28

      Spurious current emerging in the vicinity of phase interfaces is a well-known disadvantage of the lattice Boltzmann equation (LBE) for two-phase flows. Previous analysis shows that this unphysical phenomenon comes from the force imbalance at discrete level inherited in LBE (Guo et al 2011 Phys. Rev. E 83 036707). Based on the analysis of the LBE free of checkerboard effects, in this work we further show that the force imbalance is caused by the different discretization stencils: the implicit one from the streaming process and the explicit one from the discretization of the force term. Particularly, the total contribution includes two parts, one from the difference between the intrinsically discretized density (or ideal gas pressure) gradient and the explicit ones in the force term, and the other from the explicit discretized chemical potential gradients in the intrinsically discretized force term. The former contribution is a special feature of LBE which was not realized previously.

    6. O outro, o mesmo: A corrida de touros espanhola como objeto da etnologia francesa entreguerras

      Directory of Open Access Journals (Sweden)

      Luís Felipe Sobral

      Full Text Available Resumo Durante a missão etnográfica e linguística Dacar-Djibuti (1931-1933, o escritor e etnógrafo Michel Leiris demonstrou interesse, em uma carta endereçada à sua esposa em Paris, em realizar uma etnografia da corrida de touros espanhola. Tal ideia jamais se concretizou. Este artigo, orientado por um raciocínio conjectural, descreve os fatores que impediriam a realização desta ideia no âmbito da etnologia francesa, caso ela fosse colocada em prática. Mas não basta para tanto compreender somente quais eram os métodos etnográficos então vigentes e a posição de Leiris diante deles; é preciso examinar também o estatuto marginal e ambíguo da Espanha tanto na epistemologia etnológica como no regime identitário europeu, dois sistemas simbólicos que se encontram profundamente imbricados.

    7. Recent development in clusters of rare earths and actinides. Chemistry and materials

      International Nuclear Information System (INIS)

      Zheng, Zhiping

      2017-01-01

      This book contains the following eight contributions: 1. Lanthanide Hydroxide Cluster Complexes via Ligand-Controlled Hydrolysis of the Lanthanide Ions (Zhonghao Zhang, Yanan Zhang, and Zhiping Zheng); 2. Synthesis and Structures of Lanthanide-Transition Metal Clusters (Xiu-Ying Zheng, Xiang-Jian Kong, and La-Sheng Long); 3. Hydrothermal Synthesis of Lanthanide and Lanthanide-Transition-Metal Cluster Organic Frameworks via Synergistic Coordination Strategy (Jian-Wen Cheng and Guo-Yu Yang); 4. Oxo Clusters of 5f Elements (Sarah Hickam and Peter C.); 5. Construction and Luminescence Properties of 4f and d-4f Clusters with Salen-Type Schiff Base Ligands (Xiaoping Yang, Shiqing Wang, Chengri Wang, Shaoming Huang, and Richard A.); 6. 4f-Clusters for Cryogenic Magnetic Cooling (Yan-Cong Chen, Jun-Liang Liu, and Ming-Liang Tong); 7. Lanthanide Clusters Toward Single-Molecule Magnets (Tian Han, You-Song Ding, and Yan-Zhen Zheng); 8. Molecular Rare Earth Hydride Clusters (Takanori Shima and Zhaomin Hou).

    8. Markers of DNA/RNA damage from oxidation as predictors of a registry-based diagnosis of psychiatric illness in type 2 diabetic patients

      DEFF Research Database (Denmark)

      Jorgensen, Anders; Siersma, Volkert; Davidsen, Annette S.

      2018-01-01

      Oxidative stress is a potential biological mediator of the higher rates of psychiatric illness (PI) observed after the onset of type 2 diabetes (T2DM). We investigated validated urinary markers of systemic DNA/RNA damage from oxidation (8-oxodG/8-oxoGuo respectively) as predictors of incident PI......, this association was most predominant in minor PIs (unipolar depression and anxiety) compared to major PIs such as schizophrenia and bipolar disorder. These observations indicate that higher levels of systemic oxidative stress are not associated with a higher risk of PI after T2DM onset. Only PI patients treated...... in a cohort of 1381 newly diagnosed T2DM patients, who were followed prospectively for a total of 19 years after diagnosis. Psychiatric diagnoses were from Danish national registries. Patients were examined at the time of diagnosis and at a 6-year follow-up. At baseline, 8-oxodG was slightly lower in PI vs...

    9. The negative cell cycle regulator, Tob (transducer of ErbB-2), is involved in motor skill learning

      International Nuclear Information System (INIS)

      Wang Xinming; Gao Xiang; Zhang Xuehan; Tu Yanyang; Jin Meilei; Zhao Guoping; Yu Lei; Jing Naihe; Li Baoming

      2006-01-01

      Tob (transducer of ErbB-2) is a negative cell cycle regulator with anti-proliferative activity in peripheral tissues. Our previous study identified Tob as a protein involved in hippocampus-dependent memory consolidation (M.L. Jin, X.M. Wang, Y.Y. Tu, X.H. Zhang, X. Gao, N. Guo, Z.Q. Xie, G.P. Zhao, N.H. Jing, B.M. Li, Y.Yu, The negative cell cycle regulator, Tob (Transducer of ErbB-2), is a multifunctional protein involved in hippocampus-dependent learning and memory, Neuroscience 131 (2005) 647-659). Here, we provide evidence that Tob in the central nervous system is engaged in acquisition of motor skill. Tob has a relatively high expression in the cerebellum. Tob expression is up-regulated in the cerebellum after rats receive training on a rotarod-running task. Rats infused with Tob antisense oligonucleotides into the 4th ventricle exhibit a severe deficit in running on a rotating rod or walking across a horizontally elevated beam

    10. Instituição de longa permanência para idosos: um lugar de cuidado para quem não tem opção?

      Directory of Open Access Journals (Sweden)

      Janine Melo de Oliveira

      2014-10-01

      Full Text Available Pesquisa descritiva, qualitativa, com abordagem compreensiva, que teve por objetivo compreender o significado da instituição de longa permanência para idosos institucionalizados. Os dados foram coletados com 13 idosos institucionalizados, no período de 5 de abril a 25 de maio de 2013 por meio da entrevista narrativa, e submetidos a análise de conteúdo, na modalidade de análise temática. Os resultados indicam que ser idoso institucionalizado significa ter suas necessidades de cuidado atendidas, no que concerne a suas necessidades básicas; ao acesso a serviços e recursos de saúde, e a ter um lugar onde possam envelhecer e morrer. O estudo permitiu concluir que a instituição aparece como um lugar ambíguo para os idosos, pois ao mesmo tempo em que os acolhe, abriga e atende suas necessidades, é um ambiente que inviabiliza a vida independente e autônoma.

    11. Synthesizing lattice structures in phase space

      International Nuclear Information System (INIS)

      Guo, Lingzhen; Marthaler, Michael

      2016-01-01

      In one dimensional systems, it is possible to create periodic structures in phase space through driving, which is called phase space crystals (Guo et al 2013 Phys. Rev. Lett. 111 205303). This is possible even if for particles trapped in a potential without periodicity. In this paper we discuss ultracold atoms in a driven optical lattice, which is a realization of such a phase space crystals. The corresponding lattice structure in phase space is complex and contains rich physics. A phase space lattice differs fundamentally from a lattice in real space, because its coordinate system, i.e., phase space, has a noncommutative geometry, which naturally provides an artificial gauge (magnetic) field. We study the behavior of the quasienergy band structure and investigate the dissipative dynamics. Synthesizing lattice structures in phase space provides a new platform to simulate the condensed matter phenomena and study the intriguing phenomena of driven systems far away from equilibrium. (paper)

    12. Structure-based membrane dome mechanism for Piezo mechanosensitivity.

      Science.gov (United States)

      Guo, Yusong R; MacKinnon, Roderick

      2017-12-12

      Mechanosensitive ion channels convert external mechanical stimuli into electrochemical signals for critical processes including touch sensation, balance, and cardiovascular regulation. The best understood mechanosensitive channel, MscL, opens a wide pore, which accounts for mechanosensitive gating due to in-plane area expansion. Eukaryotic Piezo channels have a narrow pore and therefore must capture mechanical forces to control gating in another way. We present a cryo-EM structure of mouse Piezo1 in a closed conformation at 3.7Å-resolution. The channel is a triskelion with arms consisting of repeated arrays of 4-TM structural units surrounding a pore. Its shape deforms the membrane locally into a dome. We present a hypothesis in which the membrane deformation changes upon channel opening. Quantitatively, membrane tension will alter gating energetics in proportion to the change in projected area under the dome. This mechanism can account for highly sensitive mechanical gating in the setting of a narrow, cation-selective pore. © 2017, Guo et al.

    13. Inhaled anticholinergic use and all-cause mortality among elderly Medicare beneficiaries with chronic obstructive pulmonary disease

      Directory of Open Access Journals (Sweden)

      Ajmera M

      2013-06-01

      Full Text Available Mayank Ajmera,1 Chan Shen,2 Xiaoyun Pan,1 Patricia A Findley,3 George Rust,4 Usha Sambamoorthi1 1Department of Pharmaceutical Systems and Policy, School of Pharmacy, West Virginia University, Morgantown, WV, USA; 2Department of Biostatistics, MD Anderson Cancer Center, University of Texas, Houston, TX, USA; 3School of Social Work, Rutgers University, New Brunswick, NJ, USA; 4Department of Family Medicine, Morehouse School of Medicine, Atlanta, GA, USA Background: The purpose of this study was to examine the association between use of inhaled anticholinergics and all-cause mortality among elderly individuals with chronic obstructive pulmonary disease (COPD, after controlling for demographic, socioeconomic, health, functional status, smoking, and obesity. Methods: We used a retrospective longitudinal panel data design. Data were extracted for multiple years (2002–2009 of the Medicare Current Beneficiary Survey (MCBS linked with fee-for-service Medicare claims. Generic and brand names of inhaled anticholinergics were used to identify inhaled anticholinergic utilization from the self-reported prescription medication files. All-cause mortality was assessed using the vital status variable. Unadjusted group differences in mortality rates were tested using the chi-square statistic. Multivariable logistic regressions with independent variables entered in separate blocks were used to analyze the association between inhaled anticholinergic use and all-cause mortality. All analyses accounted for the complex design of the MCBS. Results: Overall, 19.4% of the elderly Medicare beneficiaries used inhaled anticholinergics. Inhaled anticholinergic use was significantly higher (28.5% among those who reported poor health compared with those reporting excellent or very good health (12.7%. Bivariate analyses indicated that inhaled anticholinergic use was associated with significantly higher rates of all-cause mortality (18.7% compared with nonusers (13.6%. However

    14. Novel guanidinylated bioresponsive poly(amidoamines designed for short hairpin RNA delivery

      Directory of Open Access Journals (Sweden)

      Yu J

      2016-12-01

      Full Text Available Jiankun Yu,1 Jinmin Zhang,1 Haonan Xing,1 Yanping Sun,1 Zhen Yang,1 Tianzhi Yang,2 Cuifang Cai,1 Xiaoyun Zhao,3 Li Yang,1 Pingtian Ding1 1School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China; 2Department of Basic Pharmaceutical Sciences, School of Pharmacy, Husson University, Bangor, ME, USA; 3Department of Microbiology and Cell Biology, School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China Abstract: Two different disulfide (SS-containing poly(amidoamine (PAA polymers were constructed using guanidino (Gua-containing monomers (ie, arginine [Arg] and agmatine [Agm] and N,N'-cystamine bisacrylamide (CBA by Michael-addition polymerization. In order to characterize these two Gua-SS-PAA polymers and investigate their potentials as short hairpin RNA (shRNA-delivery carriers, pSilencer 4.1-CMV FANCF shRNA was chosen as a model plasmid DNA to form complexes with these two polymers. The Gua-SS-PAAs and plasmid DNA complexes were determined with particle sizes less than 90 nm and positive ζ-potentials under 20 mV at nucleic acid:polymer weight ratios lower than 1:24. Bioresponsive release of plasmid DNA was observed from both newly constructed complexes. Significantly lower cytotoxicity was observed for both polymer complexes compared with polyethylenimine and Lipofectamine 2000, two widely used transfection reagents as reference carriers. Arg-CBA showed higher transfection efficiency and gene-silencing efficiency in MCF7 cells than Agm-CBA and the reference carriers. In addition, the cellular uptake of Arg-CBA in MCF7 cells was found to be higher and faster than Agm-CBA and the reference carriers. Similarly, plasmid DNA transport into the nucleus mediated by Arg-CBA was more than that by Agm-CBA and the reference carriers. The study suggested that guanidine and carboxyl introduced into Gua-SS-PAAs polymers resulted in a better nuclear localization effect, which played a key role in the

    15. Matematik Dersinde İsteğe Bağlı Çevrimiçi Kısa Sınav Uygulanması Hakkında Öğrenci Görüşleri

      Directory of Open Access Journals (Sweden)

      Harun ÇİĞDEM

      2014-12-01

      Full Text Available Bu çalışmanın amacı öğrencilerin harmanlanmış öğretim kapsamında kullandıkları çevrimiçi quiz sistemi hakkındaki görüşlerinin ortaya konmasıdır. Harmanlanmış öğretim, yüz yüze öğretim ile web tabanlı öğrenme yönetim sisteminin birlikte kullanılmasıyla oluşturulmuştur. Betimsel yöntem desenindeki çalışma bir meslek yüksekokulunda Matematik-I dersini alan 204 öğrenci üzerinde gerçekleştirilmiştir. Dersler sınıf ortamında yürütülmüş ve intranet üzerinden öğrencilere powerpoint (ppt sunuları, ders notları ve quizler sunulmuştur. Çevrimiçi quizler ile ünite bazlı toplam 126 maddelik çoktan seçmeli test maddesi havuzundan öğrencilerin yararlanmaları sağlanmıştır. Dönem sonunda öğrencilerin çevrimiçi quizler hakkındaki görüşlerini belirlemek amacıyla Çevrimiçi Quiz Değerlendirme Formu kullanılmıştır. Hazırlanan form, 103 öğrenci tarafından cevaplanmıştır. Verilerin analizinde frekans, ortalama ve t testi kullanılmıştır. Öğrencilerin genel olarak çevrimiçi quiz konusunda kararsız kaldıkları belirlenmiştir. Bilgisayar sahibi olan öğrencilerin bilgisayar sahibi olmayanlara göre, evinde internet bağlantısı olan öğrencilerin evinde internet bağlantısı olmayan öğrencilere göre ve daha önce web tabanlı sınav deneyimi olan öğrencilerin, web tabanlı sınav konusunda herhangi bir deneyimi olmayan öğrencilere göre çevrimiçi quizler konusunda daha olumlu oldukları bulunmuştur. Çevrimiçi quiz uygulamasının soru bankasının oluşturulmasının özellikle Matematik dersi için oldukça zaman alıcı olduğu belirlenmiştir. Uygulamanın en önemli avantajları öğrenci quizlerini okumak için gereken zamanın azalması ve kaynakların etkin kullanılmasıdır.

    16. MODERN POETRY THAT COULD/COULDN’T EXHAUST THR CLASSICAL POETICA AND SUFISM DOCTRINE FROM A MYSTIC CHANNEL MİSTİK KANALDAN SUFİZM DOKTRİNİNİ VE KLASİK ŞİİR POETİKASINI TÜKET/EMEY/EN MODERN ŞİİR

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      Hasan AKTAŞ

      2009-12-01

      Full Text Available The poetry of classical age was pouring from two main vessels as Divan and Mysticism. The poem of these two channels were standing on two strong epistemic/basic source like Quran and Tradition. Divan and mystic poetry are in a way a secular/visible and mystic/esoteric evolution of these two rooted/epistemic source. This evolution is being made confirm and classical by sealing with secrets sometimes. In a way, this caused the Divan poetry turning into a hidden treasure. Turkish poetry which suddenly lost it’s treasure with modernism, got contemporary and positivist with an agression of no borders. This marginality is stopped the modern poetry. This blockage entailed new development which was through the Divan and mystic poetry. Altough this tendency, modern poetry couldn’t exhaust Divan and mystic poetry/sufism doctrine as it produce them. Because, modern poetry hasn’t got enough power to exhaust the wonderful treasure of Divan and mystic poetry. Klasik çağın şiiri divan ve tasavvuf gibi iki ana kanaldan akıyordu. Bu iki kanalın şiiri Kur’an ve Hadis gibi çok güçlü iki epistemik/temel kaynağa dayanıyordu. Divan ve tasavvuf şiiri, bir anlamda bu iki köklü/epistemik kaynağın lâdinî/zahirî ve mistik/batınî perdeden açılımıdır. Bu açılım, zaman zaman mazmunlarla mühürlenerek sahihleştirilmiş ve klasikleştirilmiştir. Bu bir anlamda divan şiirinin gizli bir hazineye dönüşmesine yol açmıştır. Modernizm ile ansızın hazinelerini yitiren Türk şiiri, aşırı derecede sınır tanımaz bir saldırganlıkla modernleşmiş ve pozitivistleşmiştir. Bu marjinallik, kısa sürede modern şiirin önünü tıkamıştır. Bu tıkanmışlık, yeni açılımları zorunlu kılmış ve bu açılım da divan ve tasavvuf şiirine doğru olmuştur. Bu yönelişe rağmen modern şiir, mistik şiiri/sufizm doktrinini ve divan şiirini üretmesine rağmen bir türlü tüketememektedir. Zira divan şiiri ve mistik

    17. Simidin Demir ve Çinko Mineralleriyle Zenginleştirilmesi ve in vitro Mineral Biyoyararlılığının Saptanması

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      Melis Sözer Güzelcan

      2015-02-01

      Full Text Available Bu çalışmada, Türkiye’de sıklıkla görülen mineral yetersizliğine bağlı beslenme sorunlarına bir yaklaşım olması açısından geleneksel bir gıda olan simidin demir ve çinko mineralleri ile zenginleştirilmesi, bu mi­nerallerin biyoyararlılığı ve genellikle simit ile birlikte tüketilen çay ve ayran içeceklerinin mineral biyoya­rarlılığı üzerine etkileri ve ayrıca tahıllı gıdalarda bulunan fitik asidin mineral biyoyararlılığına etkisinin saptanması amaçlanmıştır. Bu amaçla, simit, demir ve çinko mineralleri ile zenginleştirilmiş simit, çay + zenginleştirilmiş simit ve ayran + zenginleştirilmiş simit örneklerinde demir ve çinko minerallerinin içe­rikleri ve in vitro mineral biyoyararlılıkları saptanmıştır. Simit, demir ve çinko mineralleri ile zenginleşti­rilmiş simit örneklerinde fitik asit içerikleri de belirlenmiştir. Çalışma sonucunda; simitteki demir ve çinko minerallerinin biyoyararlılıkları sırasıyla % 3.14 ve % 6.78; zenginleştirilmiş simitteki bu minerallerin biyo­yararlılıkları sırasıyla % 1.96 ve % 2.84 olarak saptanmıştır. Demir mineralinin biyoyararlılığı simit ayran ve çayla tüketildiği zaman sırasıyla % 2.14 ile % 2.23; çinko mineralinin biyoyararlılığı sırasıyla % 6.38 ve % 5.09 olarak belirlenmiştir. Çay ve ayran zenginleştirilmiş simit ile birlikte tüketildiği zaman demir mineralinin biyoyararlılığının değişmediği; çinko mineralinin biyoyararlılığının arttığı saptanmıştır. Simit ve zenginleş­tirilmiş simitteki fitik asit içerikleri sırasıyla 0.154 g/100g ve 0.159 g/100g olarak belirlenmiştir. Fitat:demir minerali ve fitat:çinko minerali molar oranları hesaplanarak mineral biyoyararlılığı değerlendirilmiştir.

    18. Türkiye’de Kuru Fasulye Üretiminin Mevcut Durumu ve Gelecek Dönemler Üretiminin Tahmin Edilmesi

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      Mehmet Aydoğan

      2015-12-01

      Full Text Available Bu çalışma Dünya genelinde ve Türkiye’de kuru fasulye üretim alanları, üretilen miktar, birim alana verim gibi parametrelerin mevcut durumunu ortaya koymak, Türkiye açısından gelecek dönemlerdeki değişmelerin yönünü ve üretim miktarlarını tahmin etmek amacıyla yapılmıştır. Araştırmada kullanılan veriler FAO, TÜİK ve Gıda Tarım ve Hayvancılık Bakanlığı’nın kayıtlarından elde edilmiştir. 1994 yılından günümüze kadar Türkiye kuru fasulye üretim alanları, üretim miktarları, ihracat, ithalat miktarları, yurt içi kullanım miktarları veri kabul edilerek bir zaman serisi oluşturulmuş ve gelecek dönemler arz talep dengesi Zaman Serisi Analizlerinden Çift Üstel Düzeltme Yöntemi ile tahmin edilmiştir. Gelecek beş yıllık dönemde (2015-2019, kuru fasulye üretim alanları, üretim miktarı ve ihracatında azalma, ithalat ve yurt içi kullanım miktarlarında artış olacağı öngörülmüştür. Aynı dönemler için Türkiye kuru fasulye arz miktarının kuru fasulye talebinden fazla olacağı, bu fazlalığın sebebinin de ithalattan kaynaklanacağı öngörülmektedir. Diğer bir ifade ile önümüzdeki yıllarda kuru fasulyede dışa bağımlılığın artacağı tahmin edilmektedir. Yurt içinde üretimde sürekliliğin sağlanabilmesi için yapılması gerekenlerin başında üretici gelirlerinin artırılması, üretici maliyetlerinin azaltılması ve kuru fasulye üretiminin teşvik edilmesi gelmektedir. Bunun için de özellikle dünya piyasalarındaki fiyat düşüşlerinin yaşandığı veya ürün arzının fazla olduğu yıllarda, yurt içi fiyat düşüşlerini önleyecek politikaların oluşturulması sağlanmalıdır.

    19. SST and ice sheet impacts on the MIS-13 climate

      Energy Technology Data Exchange (ETDEWEB)

      Muri, Helene; Berger, Andre; Yin, Qiuzhen; Sundaram, Suchithra [Universite catholique de Louvain, Georges Lemaitre Centre for Earth and Climate Research (TECLIM), Earth and Life Institute (ELI), Louvain la Neuve (Belgium); Voldoire, Aurore; Melia, David Salas Y. [CNRM-GAME Meteo-France/CNRS, Toulouse Cedex (France)

      2012-10-15

      As a first qualitative assessment tool, LOVECLIM has been used to investigate the interactions between insolation, ice sheets and the East Asian Monsoon at the Marine Isotopic Stage 13 (MIS-13) in work by Yin et al. (Clim Past 4:79-90, 2008, Clim Past 5:229-243, 2009). The results are in need of validation with a more sophisticated model, which is done in this work with the ARPEGE atmospheric general circulation model. As in the Earth system Model of Intermediate Complexity, LOVECLIM, ARPEGE shows that the northern hemispheric high insolation in summer leads to strong MIS-13 monsoon precipitation. Data from the Chinese Loess Plateau indicate that MIS-13 was locally a warm and humid period (Guo et al. in Clim Past 5:21-31, 2009; Yin and Guo in Chin Sci Bull 51(2):213-220, 2006). This is confirmed by these General Circulation Model (GCM) results, where the MIS-13 climate is found to be hotter and more humid both in the presence and absence of any added ice sheets. LOVECLIM found that the combined effects of the ice sheets and their accompanying SSTs contribute to more precipitation in eastern China, whilst in ARPEGE the impact is significant in northeastern China. Nonetheless the results of ARPEGE confirm the counter-intuitive results of LOVECLIM where ice sheets contribute to enhance monsoon precipitation. This happens through a topography induced wave propagating through Eurasia with an ascending branch over northeastern China. A feature which is also seen in LOVECLIM. The SST forcing in ARPEGE results in a strong zonal temperature gradient between the North Atlantic and east Eurasia, which in turn triggers an atmospheric gravity wave. This wave induces a blocking Okhotskian high, preventing the northwards penetration of the Meiyu monsoon front. The synergism between the ice sheets and SST is found through the factor separation method, yielding an increase in the Meiyu precipitation, though a reduction of the Changma precipitation. The synergism between the ice

    20. Bioinformatics analysis of differentially expressed proteins in prostate cancer based on proteomics data

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      Chen C

      2016-03-01

      Full Text Available Chen Chen,1 Li-Guo Zhang,1 Jian Liu,1 Hui Han,1 Ning Chen,1 An-Liang Yao,1 Shao-San Kang,1 Wei-Xing Gao,1 Hong Shen,2 Long-Jun Zhang,1 Ya-Peng Li,1 Feng-Hong Cao,1 Zhi-Guo Li3 1Department of Urology, North China University of Science and Technology Affiliated Hospital, 2Department of Modern Technology and Education Center, 3Department of Medical Research Center, International Science and Technology Cooperation Base of Geriatric Medicine, North China University of Science and Technology, Tangshan, People’s Republic of China Abstract: We mined the literature for proteomics data to examine the occurrence and metastasis of prostate cancer (PCa through a bioinformatics analysis. We divided the differentially expressed proteins (DEPs into two groups: the group consisting of PCa and benign tissues (P&b and the group presenting both high and low PCa metastatic tendencies (H&L. In the P&b group, we found 320 DEPs, 20 of which were reported more than three times, and DES was the most commonly reported. Among these DEPs, the expression levels of FGG, GSN, SERPINC1, TPM1, and TUBB4B have not yet been correlated with PCa. In the H&L group, we identified 353 DEPs, 13 of which were reported more than three times. Among these DEPs, MDH2 and MYH9 have not yet been correlated with PCa metastasis. We further confirmed that DES was differentially expressed between 30 cancer and 30 benign tissues. In addition, DEPs associated with protein transport, regulation of actin cytoskeleton, and the extracellular matrix (ECM–receptor interaction pathway were prevalent in the H&L group and have not yet been studied in detail in this context. Proteins related to homeostasis, the wound-healing response, focal adhesions, and the complement and coagulation pathways were overrepresented in both groups. Our findings suggest that the repeatedly reported DEPs in the two groups may function as potential biomarkers for detecting PCa and predicting its aggressiveness. Furthermore

    1. Comparison of the short-term efficacy between docetaxel plus carboplatin and 5-fluorouracil plus carboplatin in locoregionally advanced nasopharyngeal carcinoma

      Directory of Open Access Journals (Sweden)

      Lv X

      2016-08-01

      Full Text Available Xing Lv,1,2,* Wei-Xiong Xia,1,2,* Liang-Ru Ke,1,2 Jing Yang,1,2 Wen-Zhe Qiu,1,2 Ya-Hui Yu,1,2 Hu Liang,1,2 Xin-Jun Huang,1,2 Guo-Yin Liu,1,2 Qi Zeng,1,2 Xiang Guo,1,2 Yan-Qun Xiang1,2 1Key Laboratory of Oncology in South China, 2Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China *These authors contributed equally to this work Objective: Platinum-based chemotherapy in combination with radiotherapy is a standard treatment strategy for locoregionally advanced nasopharyngeal carcinoma (NPC. This study aimed to investigate the long-term efficacy and tolerability of inductive chemotherapy with docetaxel plus carboplatin (TC or 5-fluorouracil plus carboplatin (FC followed by concurrent radiation therapy in patients with NPC. Methods: Patients (N=88 were randomized to receive TC or FC as inductive therapy followed by concurrent radiotherapy (60–70 Gy with two cycles of carboplatin (area under the curve =5 mg·h/L. Patients were followed up for 8 years. Primary end point was progression-free survival (PFS. Secondary end points included overall survival (OS, toxicity, tumor response, distant metastasis-free survival, and local recurrence-free survival. Results: At the end of the follow-up period, 31 patients died, 32 had disease progression, eleven had cancer recurrence, and 25 had distant metastasis. Overall, there was no difference between treatment groups with regard to response or survival. We found that following induction and concurrent chemoradiotherapy, the majority of patients showed a complete response (~96%–98% for induction therapy and 82%–84% for comprehensive therapy to both therapies. PFS and OS were also similar between groups. The rate of PFS was 63.6% for both FC and TC and that of OS was 65.9% and 63.5%, respectively. The overall incidence of grade 3–4 adverse events in the TC group (20.5% was higher than in the FC group (10.7%. Neutropenia and leukopenia

    2. Technology Education and Technology Teacher Education in Taiwan, R.O.C. = Zhong Hua Min Guo Ke Ji Jiao Yu Ji qi shi zi Jiao Yu.

      Science.gov (United States)

      Lee, Lung-Sheng Steven; Wang, Cheng-Pin Peter; Wang, Yen-chao; Shih, Neng-Mu; Yeh, Chung-ching

      Technology education in Taiwan begins with craft work at the elementary school level, and the most important point is the practical application. All junior high school students are required to take the Living Technology course. Content includes technology and life, information and communication, construction and manufacturing, and energy and…

    3. Research Methods Used in Library and Information Science Theses: An Evaluation Kütüphanecilik ve Bilgi Bilim Tezlerinde Kullanılan Bilimsel Araştırma Yöntemleri : Bir Değerlendirme

      Directory of Open Access Journals (Sweden)

      S. Serap Kurbanoğlu

      1996-12-01

      Full Text Available A literature analysis and an evaluation are made on the findings of researches which examine the research methods employed in library science and information science dissertations. The data suggest some changes regarding to research methods used in library science dissertations. Separate examinations of library science dissertations and information science dissertations suggest that there are differences as much assimilarities between these sister disciplines. Kütüphanecilik ve bilgi bilim tezlerinde kullanılan araştırma yöntemleri konusunda yapılan araştırmaların bulguları üzerine bir literatür çalışması ve bir değerlendirme yapılmıştır. Bulgular kütüphanecilik tezlerinde kullanılan araştırma yöntemleri konusunda zaman içinde bir çeşitlenme olduğunu göstermektedir. Kütüphanecilik ve bilgi bilim tezleri üzerinde ayrı ayrı yürütülen incelemeler ise bu iki kardeş disiplin arasında benzerlikler kadar farklılıklar da olduğunu ortaya koymaktadır.

    4. ASANSÖRLERİN BİLGİSAYAR YARDlMlYLA TASARIMI ve ÇİZİMİ

      Directory of Open Access Journals (Sweden)

      Ümit KOCABIÇAK

      1998-06-01

      Full Text Available Bilgi işlem alanındaki gelişmeler sonucu olarak makina konstrüksiyonunda bilgisayar destekli tasarım programlarımn kullanımı yaygınlaşmıştır. AutoCAD gibi bilgisayar destekli tasarım programları proje zamanını kısaltmakta, konstrüksiyonla ile ilgili bütün bilgileri kısa sürede vennekte ve modelin değişik görünümlerini kolaylıkla gösterebilmektedir. Asansörlerin klasik yöntemlerle konstrüksiyonu, uzun hesaplamalar ve çizi mlerden oluşmaktadır. Bu çalışmada klasik konstrüksiyon çalışmalarının yerini almak üzere, bir yapay zeka dili olan LISP programlama dilinin AutoCAD için uyarlanmış hali olan AutoLISP kullanılarak AutoCAD R14 ortamında bir bilgisayar programı hazırlanmıştır. Geliştirilen programla, asansörlerin boyutlandırılması ve çizimi gerçekleştirilmiştir.

    5. PENINGKATAN KEMAMPUAN GURU DALAM PEMANFAATAN TEKNOLOGI INFORMASI PADA KEGIATAN PEMBELAJARAN

      Directory of Open Access Journals (Sweden)

      R. Ceha

      2016-01-01

      Full Text Available Dalam upaya peningkatan mutu mengajar dan mutu pembelajaran di era globalisasi, guru sebaiknya menguasai program komputer, agar dapat memanfaatkan teknologi yang telah tersedia dan untuk memudahkan dalam mengajar. Guru hendaknya dapat menggunakan peralatan yang lebih ekonomis, efisien, dan mampu dimiliki oleh sekolah, tidak menolak digunakannya peralatan teknologi modern yang relevan dengan tuntutan masyarakat dan perkembangan zaman, serta mempunyai berbagai keterampilan yang mendukung tugasnya dalam mengajar. Salah satu keterampilan tersebut adalah bagaimana seorang guru dapat menggunakan media pembelajaran (Syaiful Bahri, 2006. Guru dapat membuat kreasi dan variasi media interaktif, pembuatan CD pembelajaran interaktif, powerpoint, dan dengan media komputer. Masalah utama yang dihadapi mitra saat ini adalah kemampuan guru dalam pemanfaatan IT atau ICT untuk kegiatan pembelajaran belum merata. Selain itu juga masih adanya kesenjangan literasi TIK antar wilayah di satu sisi dan perkembangan internet yang juga membawa dampak negatif terhadap nilai dan norma masyarakat sehingga perlu dilakukan upaya secara aktif dari semua stakeholder sekolah dalam peningkatan kualitas pembelajaran dengan memanfaatkan teknologi informasi dan komunikasi. Kegiatan Pengabdian kepada masyarakat yang diusulkan bertujuan untuk meningkatkan pengetahuan guru mengenai pemanfaatan teknologi informasi dan komunikasi pada kegiatan pembelajaran, meningkatkan kemampuan guru untuk membuat bahan ajar pemanfaatan teknologi informasi dan komunikasi sehingga dapat mengoptimalkan potensi yang ada di sekolah mitra dalam pemanfaatan Teknologi Informasi untuk peningkatan kualitas pembelajaran

    6. Rancang Bangun Ulang Aplikasi MonTA Menggunakan Workflow Framework pada ASP.NET

      Directory of Open Access Journals (Sweden)

      Mohammad Oktri Radity

      2013-09-01

      Full Text Available Zaman sekarang kemajuan teknologi semakin berkembang pesat dari tahun ke tahun. Kebutuhan orang terhadap teknologi menjadi sangat penting. Aplikasi MonTA yang digunakan oleh jurusan Teknik Informatika ITS menjadi bukti kemajuan teknologi. Aplikasi yang dikembangkan oleh jurusan Teknik Informatika ini bertujuan untuk mengelola seluruh data tugas akhir mahasiswa Teknik Informatika. Aplikasi MonTA merupakan suatu sistem yang berkaitan dengan tugas akhir mahasiswa di jurusan Teknik Informatika, Institut Teknologi Sepuluh Nopember Surabaya. Tujuan dikembangkannya aplikasi ini adalah untuk mengelola data mahasiswa yang melaksanakan tugas akhir dan dosen dapat memonitoring mahasiswa yang sedang melakukan tugas akhir dengan aplikasi ini. Aplikasi ini juga memudahkan admin tugas akhir dalam melakukan tugasnya, antara lain: penjadwalan proposal, memonitor jumlah bimbingan mahasiswa tugas akhir, penjadwalan sidang tugas akhir, dan lain-lain. Namun, aplikasi MonTA yang sekarang digunakan masih memiliki banyak kekurangan. Oleh karena itu dibahas perancangan ulang aplikasi MonTA pada artikel ini. Metode baru yang digunakan pada rancang ulang aplikasi MonTA ini adalah dengan penerapan Workflow Framework pada ASP.NET. Diharapkan dengan rancang ulang aplikasi ini nantinya dapat memperbaiki berbagai kekurangan yang ada saat ini, seperti inkonsitensi data dan memperbaiki data yang terdapat pada  aplikasi MonTA menjadi lebih terstruktur

    7. Cucurbitane Glycosides Derived from Mogroside IIE: Structure-Taste Relationships, Antioxidant Activity, and Acute Toxicity

      Directory of Open Access Journals (Sweden)

      Lei Wang

      2014-08-01

      Full Text Available Mogroside IIE is a bitter triterpenoid saponin which is the main component of unripe Luo Han Guo fruit and a precursor of the commercially available sweetener mogroside V. In this study, we developed an enzymatic glycosyl transfer method, by which bitter mogroside IIE could be converted into a sweet triterpenoid saponin mixture. The reactant concentration, temperature, pH and buffer system were studied. New saponins with the α-glucose group were isolated from the resulting mixtures, and the structures of three components of the extract were determined. The structure-taste relationships of these derivatives were also studied together with those of the natural mogrosides. The number and stereoconfiguration of glucose groups present in the mogroside molecules were found to be the main factor to determine the sweet or bitter taste of a compound. The antioxidant and food safety properties were initially evaluated by their radical scavenging ability and via 7 day mice survival tests, respectively. The results showed that the sweet triterpenoid saponin mixture has the same favorable physiological and safety characteristics as the natural mogrosides.

    8. The determination of extinction coefficient of CuInS2, and ZnCuInS3 multinary nanocrystals.

      Science.gov (United States)

      Qin, Lei; Li, Dongze; Zhang, Zhuolei; Wang, Kefei; Ding, Hong; Xie, Renguo; Yang, Wensheng

      2012-10-21

      A pioneering work for determining the extinction coefficient of colloidal semiconductor nanocrystals (NCs) has been cited over 1500 times (W. Yu, W. Guo, X. G. Peng, Chem. Mater., 2003, 15, 2854-2860), indicating the importance of calculating NC concentration for further research and applications. In this study, the size-dependent nature of the molar extinction coefficient of "greener" CuInS(2) and ZnCuInS(3) NCs with emission covering the whole visible to near infrared (NIR) is presented. With the increase of NC size, the resulting quantitative values of the extinction coefficients of ternary CuInS(2) and quaternary ZnCuInS(3) NCs are found to follow a power function with exponents of 2.1 and 2.5, respectively. Obviously, a larger value of extinction coefficient is observed in quaternary NCs for the same size of particles. The difference of the extinction coefficient from both samples is clearly demonstrated due to incorporating ZnS with a much larger extinction coefficient into CuInS(2) NCs.

    9. Map of calculated radioactivity of fission product, 3

      International Nuclear Information System (INIS)

      Takeda, Tsuneo

      1977-02-01

      In this work, the radioactivities of fission products were calculated and summarized in contour maps and tables depending on irradiation and cooling times. The irradiation condition and other parameters used for the present calculation are shown in the followings. Neutron flux (N sub(th)): 3x10 13 n/sec/cm 2 Atom number of uranium: 1 mole (6x10 23 , ca. 271 gUO 2 ) Enrichment of U-235: 2.7% Range of irradiation time: 60-6x10 7 sec (ca. 1.9 y) Range of cooling time: 60-6x10 7 sec (ca. 1.9 y). Values of the neutron flux and the enrichment treated here are representative for common LWRs. The maps and tables of 560 nuclides are divided and compiled into the following three volumes. Vol. I: Maps of radioactivity of overall total, element total and each nuclide (Ni - Zr), Vol. II: Maps of radioactivity of each nuclide (Nb - Sb), Vol. III: Maps of radioactivity of each nuclide (Te - Tm). (auth.)

    10. Map of calculated radioactivity of fission product, (1)

      International Nuclear Information System (INIS)

      Takeda, Tsuneo

      1977-02-01

      In this work, the radioactivities of fission products were calculated and summarized in contour maps and tables depending on irradiation and cooling times. The irradiation condition and other parameters used for the present calculation are shown in the followings. Neutron flux (N sub(th)): 3x10 13 n/sec/cm 2 Atom number of uranium: 1 mole (6x10 23 , ca. 271 gUO 2 ) Enrichment of U-235: 2.7% Range of irradiation time: 60-6x10 7 sec (ca. 1.9 y) Range of cooling time: 60-6x10 7 sec (ca. 1.9 y). Values of the neutron flux and the enrichment treated here are representative for common LWRs. The maps and tables of 560 nuclides are divided and compiled into the following three volumes. Vol. I Maps of radioactivity of overall total, element total and each nuclide (Ni - Zr) Vol. II Maps of radioactivity of each nuclide (Nb - Sb) Vol. III Maps of radioactivity of each nuclide (Te - Tm) (auth.)

    11. Map of calculated radioactivity of fission product, 2

      International Nuclear Information System (INIS)

      Takeda, Tsuneo

      1977-02-01

      In this work, the radioactivities of fission products were calculated and summarized in contour maps and tables depending on irradiation and cooling times. The irradiation condition and other parameters used for the present calculation are shown in the followings. Neutron flux (N sub(th)): 3x10 13 n/sec/cm 2 Atom number of uranium: 1 mole (6x10 23 , ca. 271 gUO 2 ) Enrichment of U-235: 2.7% Range of irradiation time: 60-6x10 7 sec (ca. 1.9 y) Range of cooling time: 60-6x10 7 sec (ca. 1.9 y). Values of the neutron flux and the enrichment treated here are representative for common LWRs. The maps and tables of 560 nuclides are divided and compiled into the following three volumes. Vol. I: Maps of radioactivity of overall total, element total and each nuclide (Ni - Zr), Vol. II: Maps of radioactivity of each nuclide (Nb - Sb), Vol. III: Maps of radioactivity of each nuclide (Te - Tm). (auth.)

    12. Numerical simulation of turbulent flow and heat transfer in a parallel channel. Verification of the field synergy principle

      International Nuclear Information System (INIS)

      Tian Wenxi; Su, G.H.; Qiu Suizheng; Jia Dounan

      2004-01-01

      The field synergy principle was proposed by Guo(1998) which is based on 2-D boundary laminar flow and it resulted from a second look at the mechanism of convective heat transfer. Numerical verification of this principle's validity for turbulent flow has been carried out by very few researchers, and mostly commercial software such as FLUENT, CFX etc. were used in their study. In this paper, numerical simulation of turbulent flow with recirculation was developed using SIMPLE algorithm with two-equation k-ε model. Extension of computational region method and wall function method were quoted to regulate the whole computational region geometrically. Given the inlet Reynold number keeps constant: 10000, by changing the height of the solid obstacle, simulation was conducted and the result showed that the wall heat flux decreased with the angle between the velocity vector and the temperature gradient. Thus it is validated that the field synergy principle based on 2-D boundary laminar flow can also be applied to complex turbulent flow even with recirculation. (author)

    13. Onde tem fada, tem bruxa: posições de sujeito usadas para classificar e governar infantis e docente no currículo do 1º ano

      Directory of Open Access Journals (Sweden)

      Maria Carolina da Silva Caldeira

      Full Text Available Resumo Fadas e bruxas estão presentes no universo da alfabetização em diferentes artefatos culturais. Ao investigar o currículo de uma turma de primeiro ano do Ensino Fundamental, foi possível verificar que bruxas e fadas estão presentes também no modo como uma professora e seus (suas alunos(as narram a si mesmos(as e são narrados(as pelos(as outros(as. Este artigo analisa os modos de subjetivação colocados em funcionamento no currículo, quando se opera com esses seres mágicos, por meio da articulação e da disputa entre dois dispositivos: o da antecipação da alfabetização e o de infantilidade. Argumenta-se que, assim como fadas e bruxas são personagens ambíguos, as posições de sujeito disponibilizadas aos (às infantis e à professora também são multifacetadas, produzindo modos de subjetivação diversos e conflitantes.

    14. Beauty and cuteness in peripheral vision

      Science.gov (United States)

      Kuraguchi, Kana; Ashida, Hiroshi

      2015-01-01

      Guo et al. (2011) showed that attractiveness was detectable in peripheral vision. Since there are different types of attractiveness (Rhodes, 2006), we investigated how beauty and cuteness are detected in peripheral vision with a brief presentation. Participants (n = 45) observed two Japanese female faces for 100 ms, then were asked to respond which face was more beautiful (or cuter). The results indicated that both beauty and cuteness were detectable in peripheral vision, but not in the same manner. Discrimination rates for judging beauty were invariant in peripheral and central vision, while discrimination rates for judging cuteness declined in peripheral vision as compared with central vision. This was not explained by lower resolution in peripheral vision. In addition, for male participants, it was more difficult to judge cuteness than beauty in peripheral vision, thus suggesting that gender differences can have a certain effect when judging cuteness. Therefore, central vision might be suitable for judging cuteness while judging beauty might not be affected by either central or peripheral vision. This might be related with the functional difference between beauty and cuteness. PMID:25999883

    15. HPLC ANALYSIS FOR DETERMINATION OF CHARACTERISTICS OF FRUCTO-OLIGOSACCHARIDE SYRUPS EXTRACTED FROM JERUSALEM ARTICHOKE

      Directory of Open Access Journals (Sweden)

      Sibel (YİĞİTARSLAN YILDIZ

      2009-02-01

      Full Text Available Abstract: This study was aimed to assess the feasibility of extracting fructo-oligosaccharides (degree of polymerization of 3-6 from jerusalem artichoke tubers by solvent extraction. Together with harvest date, storage time, and peeling of the raw material it was also investigated the influence of some process parameters on final dry matter, degree of polymerization and product profile of the extracts: time (10-60 min, temperature (40-80 °C, amount of solvent (30-50 ml and citric acid concentration (0-39 mmol/L. HPLC analysis showed that the most functional extracts (2.33 were obtained with mid-February harvested, 20 day-stored whole jerusalem artichoke tubers extracted with 40 ml of water containing 26 mmol/L citric acid at 60 °C for 40 min. Under those conditions, syrups with 17g of dry matter and degree of polymerization of 6 were produced. The density, viscosity, darkness and color of the syrups were found as 0.98 g/ml, 1.1 mPa-s, 0.38, and 13.3, respectively. Keywords: Fructo-oligosaccharides, HPLC, inulin, extraction, jerusalem artichoke YER ELMASINDAN ÖZÜTLENEN FRÜKTO-OLİGOSAKKARİT ŞURUPLARININ KARAKTERİSTİK ÖZELLİKLERİNİN HPLC ANALİZİ İLE BELİRLENMESİ Özet: Bu çalışmada, yer elmasından, çözücü özütleme yöntemiyle frükto-oligosakkaritlerin (polimerizasyon derecesi 3-6 özütlenebilirliğinin fizibilitesinin tayini amaçlanmıştır. Hasat zamanı, depolama süresi ve ham maddenin soyulmasının etkilerinin yanı sıra diğer bazı proses parametrelerinin (zaman (10-60 dak, sıcaklık (40-80°C, çözücü miktarı (30-50 ml ve sitrik asit derişimi (0-39 mmol/L de sonuçtaki kuru madde, polimerizasyon derecesi ve özütteki ürün profili üzerindeki etkileri incelenmiştir. HPLC analizleri, en fonksiyonel özütün (2,33 Şubat ayı ortalarında hasat edilmiş, 20 gün depolanmış, soyulmamış yer elması yumrularının, 26 mmol/L sitrik asit içeren 40 ml suyla, 60 °C'de 40 dakika süreyle

    16. REKLAMDA PARODİ KULLANIMININ MARKA İMAJINA ETKİSİ

      Directory of Open Access Journals (Sweden)

      Nurhan TOSUN

      2016-08-01

      Full Text Available Marka iletişim çalışmalarında temel amaç, kimi zaman hedef kitlenin var olan inançlarını ve değerlerini etkileyerek kimi zaman ise yeni inanç ve değerler oluşturarak marka imajı yaratmaktır. Markalar hem kendi imajlarına katkı sağlamak hem de rakip markaların imajlarını negatif yönde etkilemek amacıyla parodi içerikli reklam mesajları üretmektedir. Parodi var olan bir eseri eleştirmek amacıyla yapısını değiştirerek hiciv, abartı ve taklit kullanmak suretiyle yeni bir eser oluşturmada kullanılan yaygın bir türdür. Bir markanın kullandığı parodi içerikli reklam iletisi kendi imajına ve rakip markaların imajlarına olumlu ya da olumsuz yönde etki etmektedir. Bu çalışmada, reklamda parodi kullanımının marka imajına etkisini saptamak amacıyla telekomünikasyon sektöründe yer alan iki markanın parodi kullanan reklamı ve parodi kullanmayan reklam filmleri incelenmiştir. Deneysel araştırma yöntemi ile gerçekleştirilen bu çalışma tek gruplu ön test ve son test analizleri ile yapılmıştır. Mevcut marka imajı ile parodi içeren reklam mesajını izledikten sonra oluşan imaj arasında farklılık olup olmadığını incelemek  çalışmamızın temel amacıdır.  Araştırmanın ön testinde marka farkındalığı, markaya yönelik tutum ve marka imajı ölçeklerinden yararlanılmıştır. Araştırmanın son testinde ise marka imajı ölçeği kullanılmıştır. Araştırmada veri toplama aracı olarak anket yöntemi kullanılarak, 131 katılımcı üzerinde gerçekleştirilmiştir. Eleştiri, hiciv ve taklit içeren parodi reklamların marka imajı boyutları olan markada sosyal duyarlılık, marka kimlik unsurları, marka değer unsurları, markanın ticari boyutu, tüketici odaklı marka ve tüketicilerde marka tutumuna etkisi araştırılmıştır.

    17. Insight into resistance mechanisms of AZD4547 and E3810 to FGFR1 gatekeeper mutation via theoretical study

      Directory of Open Access Journals (Sweden)

      Liang D

      2017-02-01

      Full Text Available Donglou Liang,1,* Qiaowan Chen,2,* Yujin Guo,1 Ting Zhang,3 Wentao Guo4 1Pharmacy Department, Jining First People’s Hospital, 2Department of Obstetrics, Affiliated Hospital of Jining Medical University, Jining, Shandong, 3Department of Rheumatology, The First Affiliated Hospital of Wenzhou Medical University, 4School of Pharmacy, Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China *These authors contributed equally to this work Abstract: Inhibitors targeting the amplification of the fibroblast growth factor receptor 1 (FGFR1 have found success in the treatment of FGFR1-positive squamous cell lung and breast cancers. A secondary mutation of gatekeeper residue (V561M in the binding site has been linked to the acquired resistance. Recently, two well-known small molecule inhibitors of FGFR1, AZD4547 and E3810, reported that the V561M mutation confers significant resistance to E3810, while retaining affinity for AZD4547. FGFR1 is widely investigated as potential therapeutic target, while there are few computational studies made to understand the resistance mechanisms about FGFR1 V561M gatekeeper mutation. In this study, molecular docking, classical molecular dynamics simulations, molecular mechanics/generalized born surface area (MM/GBSA free energy calculations, and umbrella sampling (US simulations were carried out to make clear the principle of the binding preference of AZD4547 and E3810 toward FGFR1 V561M gatekeeper mutation. The results provided by MM/GBSA reveal that AZD4547 has similar binding affinity to both FGFR1WT and FGFR1V561M, whereas E3810 has much higher binding affinity to FGFR1WT than to FGFR1V561M. Comparison of individual energy terms indicates that the major variation of E3810 between FGFR1WT and FGFR1V561M are van der Waals interactions. In addition, US simulations prove that the potential of mean force (PMF profile of AZD4547 toward FGFR1WT and FGFR1V561M has similar PMF depth. However, the PMF profile

    18. Myometrial invasion and overall staging of endometrial carcinoma: assessment using fusion of T2-weighted magnetic resonance imaging and diffusion-weighted magnetic resonance imaging

      Directory of Open Access Journals (Sweden)

      Guo Y

      2017-12-01

      Full Text Available Yu Guo,1,2 Ping Wang,2 Penghui Wang,2 Wei Gao,1 Fenge Li,3 Xueling Yang,1 Hongyan Ni,2 Wen Shen,2 Zhi Guo1 1Department of Interventional Therapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin, 2Department of Radiology, Tianjin First Center Hospital, The First Central Clinical College of Tianjin Medical University, Tianjin, 3Department of Gynecology, Tianjin First Center Hospital, Tianjin, People’s Republic of China Background: The age of onset of endometrial carcinoma has been decreasing in recent years. In endometrial carcinoma, it is important to accurately assess invasion depth and preoperative staging. Fusion of T2-weighted magnetic resonance imaging (T2WI and diffusion-weighted magnetic resonance imaging (DWI may contribute to the improvement of anatomical localization of lesions.Materials and methods: In our study, a total of 58 endometrial carcinoma cases were included. Based on the revised 2009 International Federation of Gynecology and Obstetrics staging system, a fusion of T2WI and DWI was utilized for the evaluation of invasion depth and determination of the overall stage. Postoperative pathologic assessment was considered as the reference standard. The consistency of T2WI image staging and pathologic staging, and the consistency of fused T2WI and DWI and pathologic staging were all analyzed using Kappa statistics.Results: Compared with the T2WI group, a significantly higher diagnostic accuracy was observed for myometrial invasion with fusion of T2WI and DWI (77.6% for T2WI; 94.8% for T2WI-DWI. For the identification of deep invasion, we calculated values for diagnostic sensitivity (69.2% for T2WI; 92.3% for T2WI-DWI, specificity (80% for T2WI; 95.6% for T2WI-DWI, positive predictive value (50% for T2WI; 85.7% for T2WI-DWI, and negative predictive value (90% for

    19. A novel drug–phospholipid complex enriched with micelles: preparation and evaluation in vitro and in vivo

      Directory of Open Access Journals (Sweden)

      Xia HJ

      2013-02-01

      Full Text Available Hai-jian Xia,1,2 Zhen-hai Zhang,1 Xin Jin,1 Qin Hu,1 Xiao-yun Chen,1 Xiao-bin Jia11Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing, China; 2College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, ChinaAbstract: Mixed micelles are widely used to increase solubility and bioavailability of poorly soluble drugs. One promising antitumor drug candidate is 20(S-protopanaxadiol (PPD, although its clinical application is limited by low water solubility and poor bioavailability after oral administration. In this study, we developed mixed micelles consisting of PPD–phospholipid complexes and Labrasol® and evaluated their potential for oral PPD absorption. Micelles were prepared using a solvent-evaporation method, and their physicochemical properties, including particle size, zeta potential, morphology, crystal type, drug loading, drug entrapment efficiency, and solubility, were characterized. Furthermore, in vitro release was investigated using the dialysis method, and transport and bioavailability of the mixed micelles were investigated through a Caco-2 cell monolayer and in vivo absorption studies performed in rats. Compared with the solubility of free PPD (3 µg/mL, the solubility of PPD in the prepared mixed micelles was 192.41 ± 1.13 µg/mL in water at room temperature. The in vitro release profiles showed a significant difference between the more rapid release of free PPD and the slower and more sustained release of the mixed micelles. At the end of a 4-hour transport study using Caco-2 cells, the apical-to-basolateral apparent permeability coefficients (Papp increased from (1.12 ± 0.21 × 106 cm/s to (1.78 ± 0.16 × 106 cm/s, while the basolateral-to-apical Papp decreased from (2.42 ± 0.16 × 106 cm/s to (2.12 ± 0.32 × 106. In this pharmacokinetic study, compared with the bioavailability of free PPD (area under the curve [AUC]0–8, the

    20. Şii Siyasi Düşüncesinin Şekillenmesi

      Directory of Open Access Journals (Sweden)

      Mazlum Uyar

      2015-11-01

      Full Text Available Şii ulemanın dini-fıkhi otoritenin yanısıra imamın siyasi otoritesini de temsil ettiği manasında velayet-i fakih anlayışının Humeyniden önce açık bir şekilde dile getirilmediği dikkat çekmektedir.   Şii siyasi fıkhında dönüm noktası olan gaybetten önce, masum imamların yaşamış oldukları dönem, gaybet sonrası Şii ulemanın siyasi otorite hakkındaki görüşlerinin anlaşılması bakımından önemli bir zaman dilimi olmakla birlikte, kendi içinde oldukça kapalı ve problemli bir dönemdir. Çünkü bu dönemle ilgili bilgiler 3/9 ve 4/10. yy tarihçileri tarafından doktrine dayalı birtakım sebeplerle sonradan kaleme alınmış  malumattan ibarettir. Sünni kaynaklarda da bu konudaki bilgiler yetersizdir. Bu çalışmada gaybet sonrası Şii ulemanın  siyasi otoriteyle ilgili görüş ve tavırları değerlendirmeye tabi tutulmuştur.

    1. YAPAY SİNİR AĞLARI KULLANILARAK BAĞ BUDAMA ARTIKLARINDAN ÜRETİLEN YONGA LEVHALARIN ÖZELLİKLERİNİN TAHMİN EDİLMESİ

      Directory of Open Access Journals (Sweden)

      Hüseyin GÜRÜLER

      2015-04-01

      Full Text Available Bu çalışmada, yonga levha hammaddesi olarak beş farklı oranda, bağ budama yongaları ve odun yongaları kullanılmıştır. Öncelikle küçük boyutlu numune paneller üç katmanlı olarak (56x56x2 cm üretilmiştir. Bu levhaların; fiziksel (kalınlığına şişme, su alma ve mekaniksel (eğilme direnci, elastikiyet modülü, iç yapışma ve vida tutma özellikleri belirlenmiştir. Direk ölçüm alma metodu en güvenilir metot olmasına rağmen çok karmaşık ve zaman alıcıdır. Üstelik her oran uygulanabilir değildir. Bu nedenle girdi-çıktı haritalamada en güçlü araçlar olan esnek (yazılımsal hesaplama yöntemleri tercih edilmiştir. Bu aşamada, yapay sinir ağları (YSA tahmin amaçlı kullanıldı. Sonuçlar yapay sinir ağları sisteminin zamandan ve maliyetten kazanç sağlayarak yonga levhaların özelliklerinin belirlenmesinde yetkin olduğunu göstermektedir

    2. Peperangan Generasi Digital Natives Melawan Digital Hoax Melalui Kompetisi Kreatif

      Directory of Open Access Journals (Sweden)

      Yanti Dwi Astuti

      2017-12-01

      threaten the unity and unity of the nation. Fenomena penyebaran hoax dan hate speech yang terjadi di dunia digital telah membawa kecemasan dan keprihatinan di dalam masyarakat. Banyak informasi hoax, hatespeech dan cyberbullying yang disebarkan oknum melalui Social Media dan Instant Messaging yang cenderung berbau SARA, provokatif dan bombastis. Ironisnya tidak sedikit pula masyarakat yang tanpa berpikir panjang langsung menshare informasi tersebut bahkan mereproduksi ulang informasi tanpa memikirkan dampak yang ditimbulkan setelahnya. Media digital saat ini didominasi oleh remaja yang lahir di zaman millennium yang merupakan “digital natives” yaitu generasi yang tidak dapat terpisahkan oleh dunia digital. Jika generasi ini tidak diberikan amunisi yang cukup untuk memerangi digital hoax, maka dikhawatirkan akan menimbulkan masalah dan bahaya laten. Menyikapi hal ini Prodi Ilkom UIN Sunan Kalijaga Yogyakarta melakukan kampanye anti-hoax dengan target pesertanya adalah mahasiswa yang merupakan remaja akhir dan dewasa awal yang dikemas melalui kegiatan ADUIN Fest 2017 “Nyepik Becik” (Pikirkan Apa yang Kamu Katakan” pada 17-18 Mei 2017. Metode pendekatannya dilakukan partisipatif dengan langsung mempraktekkannya melalui penciptaan karya-karya kreatif berupa Print-Ad, TVC dan film pendek oleh peserta yang dikompetisikan. Kemudian mengadakan creative seminar, pameran karya, Sharing Session dan Awarding Night. Harapannya anak-anak muda calon penerus bangsa ini menjadi cerdas, kritis dan mendapatkan pemahaman yang baik sehingga dapat memerangi digital hoax yang dapat mengancam persatuan dan kesatuan bangsa.

    3. Jihad Bunuh Diri Menurut Hadis Nabi SAW

      Directory of Open Access Journals (Sweden)

      Adynata Adynata

      2013-09-01

      Full Text Available Pada zaman sekarang sering kita mendengar dan melihat di media massa banyaknya terjadi born bunuh diri, baik di tempat-tempat fasilitas umum seperti hotel, rumah ibadah, tempat pertemuan ataupun yang terjadi di daerah peperangan seperti di Palestina ketika perang antara tentara Israel dan Palestina. Para ulama telah mengkaji tentang hukum melakukan bom bunuh diri. Mereka berbeda pendapat tentang hukumnya; ada yang membolehkan dan ada pula yang melarang secara mutlak. Ayat-ayat al­ Quran dan hadis Rasulullah SAW yang terkait dengan persoalan ini, secara zahir tampak bertentangan. Dalam sebuah hadis Beliau melarang membunuh diri dengan cara apapun dan nanti di dalam neraka Jahannam pelakunya akan disiksa dengan cara yang dilakukannya ketika membunuh dirinya serta kekal di dalamnya. Sementara dalam Hadis yang lain disebutkan Rasulullah SAW menawarkan kepada satu orang sahabatnya untuk melawan musuh yang banyak yang diyakini akan membawa kematiannya pada perang Uhud sehingga terkesan sahabat tersebut mengorbankan dirinya. Hadis-hadis yang tampak bertentangan ini perlu dikaji lebih mendalam untuk ditemukan relevansinya dengan peristiswa born bunuh diri yang banyak terjadi sekarang. Penulis memahami bahwa bom bunuh diri pada prinsipnya diharamkan, tetapi jika dilakukan dalam kondisi terpaksa dalam medan peperangan untuk menyelamatkan pasukan dan menghindarkan bahaya yang lebih besar lagi maka boleh dilakukan asalkan atas perintah pemimpin perang. tetapi jika dilakukan tidak kondisi perang maka tidak boleh dilakukan dan termasuk sikap putus asa terhadap kemaksiatan yang terjadi

    4. AutoLISP KULLANILARAK ÜÇ KOLLU ROBOTUN HAREKET SİMÜLASYONU

      Directory of Open Access Journals (Sweden)

      Mustafa BOZDEMİR

      2000-01-01

      Full Text Available İstenilen görev ve amaca en uygun biçimde robot geliştirmek tasarımcılar için çok büyük önem taşır. Diğer bir deyişle üzerinde çok uğraşıldığı halde tasarlanan robotlar her zaman görev yerlerinde başarılı olmayabilir. Bu nedenle tasarımı düşünülen robot sistemlerin imalinden önce, bir simülasyon programı hazırlanarak, iş alanının incelenmesi, yörünge planlamasının yaptırılması, tasarımcıya eğer var ise yanlışlıkların daha robot yapılmadan giderilmesi imkanını sağlayabilir. Bu konuda AutoCAD programının içerisinde bulunan AutoLISP programlama dili kullanılarak, üç kollu bir robotun hareket simülasyonu yapılmıştır. Simülasyon denklemlerinde analitik ve matris çözüm metotları kullanılmıştır.

    5. Sığır Etinde Su Tutma Kapasitesi ve Serbest Su Oranı Değişimi Üzerine bir Araştırma

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      Aydın Öztan

      2015-02-01

      Full Text Available Kesimden sonra ette pH değişimi, etin serbest su oranı ve su tutma kapasitesinin belirlenmesinde en önemli kriterdir. Bu araştırmada; 12 adet sığır karkasında M. Trapezius kasında kesimde, kesimden 1 saat 24 saat ve 48 saat sonra pH ölçümleri yapılmış, kompressium yöntemi ile serbest su oranı ve üç farklı yöntemle su tutma kapasitesi saptanmıştır. Pres yönteminde; süzgeç kağıtlarında toplam su alanı (T ve et alanı (Ev ek scanner ile taranmış, bilgisayarda alan ölçümleri yapılmıştır. PH-değeri bakımından zaman ve hayvan değişkenleri önemli bulunmuştur. Ette serbest su oranı rigor mortis döneminde (24 saat artmış, daha sonra düşmeye başlamıştır. Örneklerde su tutma kapasitesi kesimden başlayarak olgunlaşma periyodunda rigor mortis sonuna kadar düşmüş, daha sonra yükselmeye başlamıştır.

    6. KOMUNIKASI POLITIK DALAM NASKAH DRAMA PANEMBAHAN RESO KARYA RENDRA

      Directory of Open Access Journals (Sweden)

      Tengku Muhammad Sum

      2016-10-01

      Full Text Available AbstrakPenelitian ini sebenarnya ingin menelusuri bagaimana komunikasi politik yang terkandung dalam cerita naskah drama Panembahan Reso yang di tulis oleh Rendra. Didalam penelitian ini, menggunakan metode kualitatif dengan pendekatan teks konteks  dengan menafsirkan teks naskah drama itu sendiri. Dari penelitian yang dilakukan kita dapat  melihat komunikasi politik yang berlangsung dari Panembahan Reso yaitu, Suatu dialog komunikasi politik yang sangat keras dan tegas yang disampaikan  Raja Tua terhadap keadaan yang ada. Bahwa dia akan menghabisi semua lawan lawan politik, yang tidak sepaham dengannya. Hal ini sangat sesuai dengan dengan zaman kekuasaan rezim Orde Baru, dimana Soeharto berkuasa selama mungkin menggunakan Golkar sebagai mesin politiknya dan militer sebagai alat kekuatannya. Kata kunci:  Komunikasi politik, Naskah Drama Panembahan Reso.AbstractThis study aims to investigate politic communication that is used in script of Panembahan Reso, a drama by Rendra. This study uses qualitative method and close reading of the text itself.The result shows that politic communication in Panembahan Reso is a sharp and explicit script that is conveyed by an old King to a reality, which means he would any way he could to counter his opposition. The condition is similar with new order regime when Soeharto reigned as Indonesian President and used Golkar as his political vehicle and army as his power. Key words:  Politic Communication,Script,Panembahan Reso

    7. ULUSLARARASI PORTFÖY YÖNETIMINDE REJIM GEÇIŞKEN KARAR DESTEK MODELLERI: GELIŞMEKTE OLAN MENKUL KIYMET PIYASALARI ÜZERINE BIR UYGULAMA

      Directory of Open Access Journals (Sweden)

      Kadir TUNA

      2014-04-01

      Full Text Available Bu makale, portföy yatırımlarında bir karar destek sistemi olarak rejim geçişken modellerin ne şekilde kullanılabileceğini gelişmekte olan hisse senedi piyasalarına ait zaman serilerini ve Gauss yazılım programını kullanarak incelemektedir. Yönetim bilişim sistemlerinde, model riskinin minimize edilmesi, karar destek siteminin uygulanacağı problemin net olarak tanımlanması ve bu problemin çözümünde kullanılacak modelin doğru seçilmesi ile mümkündür. Ekonometrik testlerin sonuçları, Ukrayna hariç, gelişmekte olan ekonomilerde hisse senetleri piyasalarında 09/01/2004-13/09/2007 tarihleri arasında, ABD hisse senedi piyasaları ile karşılaştırıldığında kalıcı bir volatilitenin gözlemlendiğini ortaya koymaktadır. Bu kapsamda, Türkiye, Rusya, Ukrayna, Brezilya, Lübnan, ABD (Dow Jones Industrial Average ve MSCI (Morgan Stanley Composite Index hisse senedi piyasalarında rejim geçişkenliği ekonometrik olarak karşılaştırmalı incelenmiştir.

    8. A HYBRID GENETIC ALGORITHM FOR THE QUADRATIC ASSIGNMENT PROBLEM ON GRAPHICS PROCESSING UNITS

      Directory of Open Access Journals (Sweden)

      ERDENER ÖZÇETİN

      2016-04-01

      Full Text Available Bu çalışmada karesel atama probleminin çözümü için melez bir genetik algoritma önerilmiştir. Önerilen algoritmanın en zaman alıcı bölümleri amaç fonksiyonun hesaplanması ve yerel arama operatörüdür. Bu nedenle algoritmanın söz konusu bölümlerinin paralelleştirilmesi ve grafik işlem birimleri üzerinde uygulanması üzerinde durulmuştur. Algoritmanın seri ve paralel versiyonu 49 adet literatür problemi üzerinde test edilmiş ve karşılaştırmalar yapılmıştır. Test edilen literatur problemlerinden 34'ü için bilinen en iyi sonuçlara ulaşılmıştır. Deneysel çalışmalar önerilen algoritmanın kısa sürede etkin sonuçlar verebildiğini ortaya koymuştur. Önerilen paralel algoritmanın ortalama 17 kat olmak üzere 51 kata kadar seri algoritmaya göre hızlı çalıştığı raporlanmıştır

    9. THE EFFECT OF WINDOW FUNCTIONS ON THE ARMA MODEL PARAMETERS ESTIMATED BY PORLA METHOD

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      Şaban ÖZER

      2002-02-01

      Full Text Available PORLA metodu ile tahmin edilen ARMA model parametreleri üzerinde pencere fonksiyonlarının etkisi, sunulmuştur. PORLA metotu, izleme ve modelleme problemlerinin bağımsız alt-algoritmalar olarak düşünüldüğü bir algoritma yapısına sahiptir. Bu metotda, ilk olarak durağan olmayan veri izlemesi, giriş/çıkış veri kovaryans blok matrisinin zaman ardışımlı hesaplanması ile gerçekleştirilir. İkinci olarak, modelleme problemi, ARMA modelleme probleminin içerildiği iki-kanallı PORLA metodu ile çözülür. Zamanla hata yayılımı, PORLA metodunda oluşamaz. İsteğe bağlı pencereleme teknikleri, izleme kapasitesini ve hızlıbaşlamayı kontrol etmek için kolayca dahil edilebilir. PORLA metodu ile tahmin edilen ARMA model parametreleri üzerinde pencere fonksiyonlarının etkisini göstermek için, dikdörtgen, üçgen, Bartlett, Hanning, Hamming, üstel, değiştirilmiş Barnwell, Blackman ve Kaiser gibi farklı pencere fonksiyonları kullanılarak elde edilen benzetim sonuçları verilmiştir.

    10. Web Tabanlı Eğitimde Veri Madenciliği

      Directory of Open Access Journals (Sweden)

      Tuncay Sevindik

      2012-12-01

      Full Text Available Günümüzde, web tabanlı eğitim ortamları klasik bir içerik yapılanma sistemi ile yürütülmektedir. Ancak, tüm dünyadaki en önemli eksikliklerden biri de öğrencilerin web platformundaki davranışlarının analiz edilememesidir. En yüksek performansın sistemden elde edilebilmesi için sistem gereksinimleri, zaman içerisinde kullanıcıların taleplerindeki değişimler ve hayatın getirmiş olduğu yeniliklere açık tasarım gibi birçok durum web tabanlı uzaktan eğitim sistemlerinin tasarlanmasında önemli birer faktördür. Bu sebeplerden ötürü, web tabanlı uzaktan eğitim sistemlerinin iyi bir şekilde analiz edilmeleri ve gereksinimlere cevap verebilecek seviyede olmaları şarttır. Bu amaçla internet ve web tabanlı uzaktan eğitim sistemlerinde ihtiyaçlarımıza cevap verebilecek en önemli uygulamalardan biri de veri madenciliği ve yöntemlerinin kullanılmasıdır.Anahtar Kelimeler: Uzaktan Eğitim, web tabanlı eğitim, veri madenciliği

    11. Advances and synergy of high pressure sciences at synchrotron sources

      International Nuclear Information System (INIS)

      Liu, H.; Ehm, L.; Duffy, T.; Crichton, W.; Aoki, K.

      2009-01-01

      Introductory overview to the special issue papers on high-pressure sciences and synchrotron radiation. High-pressure research in geosciences, materials science and condensed matter physics at synchrotron sources is experiencing growth and development through synergistic efforts around the world. A series of high-pressure science workshops were organized in 2008 to highlight these developments. One of these workshops, on 'Advances in high-pressure science using synchrotron X-rays', was held at the National Synchrotron Light Source (NSLS), Brookhaven National Laboratory, USA, on 4 October 2008. This workshop was organized in honour of Drs Jingzhu Hu and Quanzhong Guo in celebration of their retirement after up to 18 years of dedicated service to the high-pressure community as beamline scientists at X17 of NSLS. Following this celebration of the often unheralded role of the beamline scientist, a special issue of the Journal of Synchrotron Radiation on Advances and Synergy of High-Pressure Sciences at Synchrotron Sources was proposed, and we were pleased to invite contributions from colleagues who participated in the workshop as well as others who are making similar efforts at synchrotron sources worldwide.

    12. WHITE-DWARF-MAIN-SEQUENCE BINARIES IDENTIFIED FROM THE LAMOST PILOT SURVEY

      International Nuclear Information System (INIS)

      Ren Juanjuan; Luo Ali; Li Yinbi; Wei Peng; Zhao Jingkun; Zhao Yongheng; Song Yihan; Zhao Gang

      2013-01-01

      We present a set of white-dwarf-main-sequence (WDMS) binaries identified spectroscopically from the Large sky Area Multi-Object fiber Spectroscopic Telescope (LAMOST, also called the Guo Shou Jing Telescope) pilot survey. We develop a color selection criteria based on what is so far the largest and most complete Sloan Digital Sky Survey (SDSS) DR7 WDMS binary catalog and identify 28 WDMS binaries within the LAMOST pilot survey. The primaries in our binary sample are mostly DA white dwarfs except for one DB white dwarf. We derive the stellar atmospheric parameters, masses, and radii for the two components of 10 of our binaries. We also provide cooling ages for the white dwarf primaries as well as the spectral types for the companion stars of these 10 WDMS binaries. These binaries tend to contain hot white dwarfs and early-type companions. Through cross-identification, we note that nine binaries in our sample have been published in the SDSS DR7 WDMS binary catalog. Nineteen spectroscopic WDMS binaries identified by the LAMOST pilot survey are new. Using the 3σ radial velocity variation as a criterion, we find two post-common-envelope binary candidates from our WDMS binary sample

    13. SAPS simulation with GITM/UCLA-RCM coupled model

      Science.gov (United States)

      Lu, Y.; Deng, Y.; Guo, J.; Zhang, D.; Wang, C. P.; Sheng, C.

      2017-12-01

      Abstract: SAPS simulation with GITM/UCLA-RCM coupled model Author: Yang Lu, Yue Deng, Jiapeng Guo, Donghe Zhang, Chih-Ping Wang, Cheng Sheng Ion velocity in the Sub Aurora region observed by Satellites in storm time often shows a significant westward component. The high speed westward stream is distinguished with convection pattern. These kind of events are called Sub Aurora Polarization Stream (SAPS). In March 17th 2013 storm, DMSP F18 satellite observed several SAPS cases when crossing Sub Aurora region. In this study, Global Ionosphere Thermosphere Model (GITM) has been coupled to UCLA-RCM model to simulate the impact of SAPS during March 2013 event on the ionosphere/thermosphere. The particle precipitation and electric field from RCM has been used to drive GITM. The conductance calculated from GITM has feedback to RCM to make the coupling to be self-consistent. The comparison of GITM simulations with different SAPS specifications will be conducted. The neutral wind from simulation will be compared with GOCE satellite. The comparison between runs with SAPS and without SAPS will separate the effect of SAPS from others and illustrate the impact on the TIDS/TADS propagating to both poleward and equatorward directions.

    14. Blue-Green Colour Categorisation in Mandarin-English Speakers

      Directory of Open Access Journals (Sweden)

      Emily Joanne Hird

      2012-05-01

      Full Text Available Observers are faster to detect a target among a set of distracters if the targets and distracters come from different colour categories. This cross-boundary advantage seems to be limited to the right visual field, which is consistent with the dominance of the left hemisphere for language processing. Here we study whether a similiar visual field advantage is found in Mandarin, a language which uses a logographic system. Forty late Mandarin-English bilinguals performed a blue-green colour categorisation task, in a blocked design, in their first language (L1: Mandarin or second language (L2: English. Eleven colour singletons ranging from blue to green were presented for 160ms, randomly in the left visual field (LVF or in the right visual field (RVF. We find that reaction times at the colour boundary were on average about 100 ms shorter in the LVF compared to the RVF, but only when the task was preformed in Mandarin as opposed to English. The apparent discrepancy with previous findings is conceivably due to the script nature of two languages: Mandarin logographic characters are analysed visuo-orthographically in the right fusiform gyrus [Guo and Burgund 2010, Brain Lang 115].

    15. True-and-error models violate independence and yet they are testable

      Directory of Open Access Journals (Sweden)

      Michael H. Birnbaum

      2013-11-01

      Full Text Available Birnbaum (2011 criticized tests of transitivity that are based entirely on binary choice proportions. When assumptions of independence and stationarity (iid of choice responses are violated, choice proportions could lead to wrong conclusions. Birnbaum (2012a proposed two statistics (correlation and variance of preference reversals to test iid, using random permutations to simulate p-values. Cha, Choi, Guo, Regenwetter, and Zwilling (2013 defended methods based on marginal proportions but conceded that such methods wrongly diagnose hypothetical examples of Birnbaum (2012a. However, they also claimed that ``true and error'' models also satisfy independence and also fail in such cases unless they become untestable. This article presents correct true-and-error models; it shows how these models violate iid, how they might correctly identify cases that would be misdiagnosed by marginal proportions, and how they can be tested and rejected. This note also refutes other arguments of Cha et al. (2013, including contentions that other tests failed to violate iid ``with flying colors'', that violations of iid ``do not replicate'', that type I errors are not appropriately estimated by the permutation method, and that independence assumptions are not critical to interpretation of marginal choice proportions.

    16. Cloning and expression of human deoxycytidine kinase cDNA

      International Nuclear Information System (INIS)

      Chottiner, E.G.; Shewach, D.S.; Datta, N.S.; Ashcraft, E.; Gribbin, D.; Ginsburg, D.; Fox, I.H.; Mitchell, B.S.

      1991-01-01

      Deoxycytidine (dCyd) kinase is required for the phosphorylation of several deoxyribonucleosides and certain nucleoside analogs widely employed as antiviral and chemotherapeutic agents. Detailed analysis of this enzyme has been limited, however, by its low abundance and instability. Using oligonucleotides based on primary amino acid sequence derived from purified dCyd kinase, the authors have screened T-lymphoblast cDNA libraries and identified a cDNA sequence that encodes a 30.5-kDa protein corresponding to the subunit molecular mass of the purified protein. Expression of the cDNA in Escherichia coli results in a 40-fold increase in dCyd kinase activity over control levels. Northern blot analysis reveals a single 2.8-kilobase mRNA expressed in T lymphoblasts at 5- to 10-fold higher levels than in B lymphoblasts, and decreased dCyd kinase mRNA levels are present in T-lymphoblast cell lines resistant to arabinofuranosylcytosine and dideoxycytidine. These findings document that this cDNA encodes the T-lymphoblast dCyd kinase responsible for the phosphorylation of dAdo and dGuo as well as dCyd and arabinofuranosylcytosine

    17. Invertendo a “Passagem Atlântica”: O “regresso” de Richard Wright a África

      Directory of Open Access Journals (Sweden)

      Ana Luísa Saraiva

      2012-10-01

      Full Text Available O texto discute o sentido polémico do “regresso” a África que Richard Wright inscreve em Black Power e a forma como a narrativa da viagem subverte a “Middle Passage”. O sujeito narrativo orienta o leitor através de uma incursão pessoal nos muitos sentidos da modernidade e desdobra a noção de “destino comum”, já apontada em 12 Million Black Voices. Contudo, qualquer sentido de comunidade é aqui necessariamente ambíguo, por estar sempre relacionado com questões de raça e identidade. Black Power é uma narrativa importante para o conceito de modernidade e assinala uma mudança significativa na produção literária de Wright para uma vertente não-ficcional. Esta segunda fase da sua obra contém, no entanto, um paradoxo crucial: enquanto se volta para o exterior, para o mundo mais global, Wright tenta, simultaneamente, inscrever-se como referência sobre o locus do qual nunca poderia demarcar‑se: África. Em Black Power, a duboisiana “color line” desdobra‑se em múltiplas dimensões.

    18. Fundamental effects of PD-1 antibody on the body: a brief report

      Directory of Open Access Journals (Sweden)

      Wang W

      2016-07-01

      Full Text Available Wei Wang,1 Bing Liu,1 Guangxian Liu,1 Wanfeng Guo2 1Cancer Therapy Center, 2Department of Healthcare and Medicine, Affiliated Hospital of the Academy of Military Medical Sciences, Beijing, People’s Republic of China Abstract: We report the case of a 61-year-old man with squamous cell carcinoma of the left lung and mediastinal lymph node metastases who received nivolumab and experienced a better antitumor effect than expected but died soon afterward. A clinical analysis showed that the grades of the treatment-related events did not cause death. The immunological impact of this treatment on his body, especially at his age and with concurrent infection, possibly augmented by the blockade of the PD-1/PD-L1 signaling pathway, is proposed to be one of the key factors for his death. Consequently, we suggest that the cellular immune status and the clinical characteristics of patients, especially the symptoms like concurrent infection, should be considered in the design of clinical protocol of such a kind of therapy. Keywords: lung cancer, PD-1, nivolumab, immunotherapy, lung infection, immunosuppression

    19. Evaluation and improvement of doctor–patient communication competence for emergency neurosurgeons: a standardized family model

      Directory of Open Access Journals (Sweden)

      Wu X

      2014-06-01

      Full Text Available Xi Wu,1 Zhinong Wang,2 Bo Hong,1 Shengjuan Shen,3 Yan Guo,4 Qinghai Huang,1 Jianmin Liu1 1Department of Neurosurgery, Changhai Hospital, Shanghai, People’s Republic of China; 2Department of Surgical Education, Changhai Hospital, Changzheng Hospital, Shanghai, People’s Republic of China; 3Department of Medical Education, The Second Military Medical University, Shanghai, People’s Republic of China; 4Department of Internal Medicine, Changhai Hospital, Shanghai, People’s Republic of China Abstract: Disease treatments have been significantly influenced by the communications between patients, their families, and doctors the lack of which may lead to malpractice allegations and complaints. In particular, inadequate communication may delay diagnosis and treatment. Therefore, for doctors communication and interpersonal skills, are as important as clinical skills and medical knowledge. In this study we intended to develop two detailed communication content checklists and a modified interpersonal skills inventory, aiming to evaluate their integrity in the midst of communication skills assessments, to provide feedback for some participants, and to observe their communication competence in both aspects Keywords: standardized patient, communication skill, training, medical education, neurosurgeon

    20. Communication: A benchmark-quality, full-dimensional ab initio potential energy surface for Ar-HOCO

      International Nuclear Information System (INIS)

      Conte, Riccardo; Bowman, Joel M.; Houston, Paul L.

      2014-01-01

      A full-dimensional, global ab initio potential energy surface (PES) for the Ar-HOCO system is presented. The PES consists of a previous intramolecular ab initio PES for HOCO [J. Li, C. Xie, J. Ma, Y. Wang, R. Dawes, D. Xie, J. M. Bowman, and H. Guo, J. Phys. Chem. A 116, 5057 (2012)], plus a new permutationally invariant interaction potential based on fitting 12 432 UCCSD(T)-F12a/aVDZ counterpoise-corrected energies. The latter has a total rms fitting error of about 25 cm −1 for fitted interaction energies up to roughly 12 000 cm −1 . Two additional fits are presented. One is a novel very compact permutational invariant representation, which contains terms only involving the Ar-atom distances. The rms fitting error for this fit is 193 cm −1 . The other fit is the widely used pairwise one. The pairwise fit to the entire data set has an rms fitting error of 427 cm −1 . All of these potentials are used in preliminary classical trajectory calculations of energy transfer with a focus on comparisons with the results using the benchmark potential

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