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Sample records for zachary jm mohide

  1. Zachary Solomon's Aggressions In Achieving Apotheosis Depicted In dan Brown's The Lost Symbol

    OpenAIRE

    FAIDAH, IRNA NUR

    2014-01-01

    Keywords: Aggression, Apotheosis, Hierarchy of Needs, The Lost Symbol, Self-Actualization, Zachary Solomon The basic concept of self-actualization is that people tend to be the best that they can be. This phenomenon is also portrayed in Dan Brown's The Lost Symbol. The Lost Symbol deals with a character named Zachary Solomon who wants to transform into status of God or it is called as apotheosis. In achieving the apotheosis, Zachary Solomon should satisfy his needs according to Abraham Masl...

  2. Radiopotentiation by the oral platinum agent, JM216: role of repair inhibition

    International Nuclear Information System (INIS)

    Amorino, George P.; Freeman, Michael L.; Carbone, David P.; Lebwohl, David E.; Choy, Hak

    1999-01-01

    Purpose: To test for in vitro radiopotentiation by the orally-administered platinum (IV) complex, JM216; to compare these results to cisplatin and carboplatin; and to investigate whether the mechanism of radiopotentiation involves repair inhibition of radiation-induced DNA damage. Methods and Materials: H460 human lung carcinoma cells were incubated with the drugs for 1 h at 37 deg. C, irradiated at room temperature, and returned to 37 deg. C for 20 min. Cells were then rinsed and colony forming ability was assessed. Wild-type V79 Chinese hamster cells and radiosensitive, DNA repair-deficient mutant cells (XR-V15B) were also studied along with H460 cells. Ku86 cDNA, which encodes part of a protein involved in DNA repair, was transfected into XR-V15B cells as previously described. The effect of JM216 on sublethal damage repair (SLDR) was also assessed using split-dose recovery. Results: Using equally cytotoxic doses of JM216, cisplatin, and carboplatin, the radiation dose enhancement ratios (DER) were 1.39, 1.31, and 1.20, respectively; the DER with 20 μM JM216 was 1.57. JM216 (20 μM) did not significantly change the final slope of radiation survival curves, but greatly reduced the survival curve shoulder. V79 cells also showed radioenhancement using 20 μM JM216, but no enhancement occurred using XR-V15B cells. Transfection of Ku86 cDNA into XR-V15B cells restored radiopotentiation by JM216 to wild-type V79 levels. In addition, 20 μM JM216 completely inhibited sublethal damage repair in H460 cells. Conclusion: Our results show that JM216 can potentiate the effects of radiation in human lung cancer cells, and that the mechanism of this effect is probably inhibition of DNA repair by JM216

  3. Semiclassical analysis of jmj'm' transitions in rotationally inelastic collisions in cell experiments

    Science.gov (United States)

    Price, T. J.; Hickman, A. P.

    2018-02-01

    Recent quantum calculations of rotationally inelastic collisions of NaK (A1Σ+) with He or Ar in a cell experiment are analyzed using semiclassical approximations valid for large quantum numbers. The results suggest a physical interpretation of jmj'm' transitions based on the vector model and lead to expressions that explicitly involve the initial and final polar angles of the angular momentum of the target molecule. The relation between the polar angle θ and the azimuthal quantum number m links the semiclassical results for the change in polar angle (θ → θ') to quantum results for an m → m' transition. Analytic formulas are derived that relate the location and width of peaks in the final polar angle distribution (PAD) to the K-dependence of the coefficients dK(j, j'), which are proportional to tensor cross sections σK(j → j'). Several special cases are treated that lead to final PADs that are approximately Lorentzian or sinc functions centered at θ' = θ. Another interesting case, "angular momentum reversal," was observed in the calculations for He. This phenomenon, which involves a reversal of the direction of the target's angular momentum, is shown to be associated with oscillatory behavior of the dK for certain transitions. Finally, several strategies for obtaining the dK coefficients from experimental data are discussed.

  4. Therapeutic potential of the novel hybrid molecule JM-20 against focal cortical ischemia in rats

    Directory of Open Access Journals (Sweden)

    Yanier Núñez Figueredo

    2016-08-01

    Full Text Available Context: Despite the great mortality and morbidity of stroke, treatment options remain limited. We previously showed that JM-20, a novel synthetic molecule, possessed a strong neuroprotective effect in rats subjected to transient middle cerebral artery occlusion. However, to verify the robustness of the pre-clinical neuroprotective effects of JM-20 to get good prognosis in the translation to the clinic, it is necessary to use other experimental models of brain ischemia. Aims: To evaluate the neuroprotective effects of JM-20 following the onset of permanent focal cerebral ischemia induced in rats by thermocoagulation of blood into pial blood vessels of cerebral cortices. Methods: Ischemic lesion was induced by thermocoagulation of blood into pial blood vessels of primary motor and somatosensory cortices. Behavioral performance was evaluated by the cylinder testing for a period of 2, 3 and 7 days after surgery, and was followed by histopathological study in brain cortex stained with hematoxylin- eosin. Results: Ischemic injury resulted in impaired function of the forelimb evidenced by high asymmetry punctuation, and caused histopathological alterations indicative of tissue damage at cerebral cortex. JM-20 treatment (4 and 8 mg/kg significantly decreased asymmetry scores and histological alterations with a marked preservation of cortical neurons. Conclusions: The effects of permanent brain ischemia were strongly attenuated by JM-20 administration, which expands and improves the current preclinical data of JM-20 as neuroprotector against cerebral ischemia, and strongly support the examination of its translation to the clinic to treat acute ischemic stroke.

  5. Brosimacutins J-M, four new flavonoids from Brosimum acutifolium and their cytotoxic activity.

    Science.gov (United States)

    Takashima, Junko; Komiyama, Kanki; Ishiyama, Haruaki; Kobayashi, Jun'ichi; Ohsaki, Ayumi

    2005-07-01

    Four new flavonoids, brosimacutins J-M (1 - 4), were isolated from the bark of Brosimum acutifolium Huber together with a known flavan, brosimine A (5). The structures of compounds 1-4 were elucidated by spectroscopic means. 27 constituents of this plant including compounds 1-5 were evaluated for their cytotoxic activity against murine leukemia P388 cells. Although no compounds tested had any reversal effect on vincristine resistance, brocimacutins J-M (1-4) were cytotoxic to vincristine-resistant P388 cells (IC50 4.4 - 19 microg/mL).

  6. Narrative authority in J.M. Coetzee's Age of Iron | Duncan | Tydskrif ...

    African Journals Online (AJOL)

    PROMOTING ACCESS TO AFRICAN RESEARCH ... This paper explores the complex nature of narrative authority in J.M. Coetzee's Age of Iron ... in fact exist, that it is only through the subjective discourse of storytelling – a discourse, however, ...

  7. Transcutaneous bilirubin--comparing the accuracy of BiliChek(R) and JM 103(R) in a regional postnatal unit.

    LENUS (Irish Health Repository)

    Qualter, Yvonne M

    2012-01-31

    OBJECTIVE: Transcutaneous bilirubin (TcB) has the potential to reduce serum bilirubin sampling. During a recent survey on the use of TcB in postnatal units in the Republic of Ireland, we identified that only 58% of the 19 units were using TcB and that only two devices were in use, the BiliChek(R) and JM 103(R). We aimed to evaluate and compare these two devices in a regional postnatal unit. METHODS: To evaluate and compare the accuracy of the BiliChek(R) and JM 103(R), we studied simultaneous TcB and total serum bilirubin (TSB) measurements from a population of jaundiced term and near term infants. We evaluated each device with regard to correlation with TSB and potential to safely reduce serum bilirubin testing. RESULTS: Both TcB devices strongly correlated with TSB (r = 0.88 for BiliChek(R) and r = 0.70 for JM 103(R). The BiliChek(R) and JM 103(R) were accurate up to cut-off values of 200 mumol\\/L and 180 mumol\\/L, respectively. Using Bhutani\\'s nomogram, 100% sensitivity was achieved using the 75th percentile for BiliChek(R) and the 40th percentile for JM 103(R). CONCLUSION: Both TcB devices correlated closely with moderately increased TSB levels and are suitable screening tools to identify jaundiced infants that require a serum bilirubin, with upper limit cut-off values. Both devices reduced the need for TSB levels. We found the BiliChek(R) slightly more accurate than the JM 103(R) for our study population. TcB however, is not in widespread use.

  8. Frère Zacharie de Vitré Récollet, Les Essais de méditations poétiques sur la passion, mort et résurrection de Notre-Seigneur Jésus-Christ

    OpenAIRE

    Mastroianni, Michele

    2017-01-01

    Interessante esempio di poesia devozionale e meditativa sulla passione, morte e resurrezione di Cristo, gli Essais des méditations poétiques di Frère Zacharie de Vitré Récollet, predicatore e teologo francescano, protetto di Camille de Neufville, arcivescovo di Lione, escono per la prima volta a Parigi nel 1659 per i tipi di François Muguet e, in seconda edizione a Lione, nel 1660, per l’editore Alexandre Fumeux. La raccolta, di 429 poemi (348 sonetti e 81 epigrammi), riunisce testi poetici p...

  9. Disturbing Reading: J.M. Coetzee's "The Problem of Evil"

    Science.gov (United States)

    Tarc, Aparna Mishra

    2011-01-01

    A literary representation can give us grief. J.M. Coetzee's "The Problem of Evil" follows the crisis of reading of his main character Elizabeth Costello as she struggles to comprehend discursive images of evil. Costello's trouble with reading is not attributed to a cognitive deficiency in her ability to read the text but to a psychical…

  10. The Glycosylphosphatidylinositol-Anchored Variable Region of Llama Heavy Chain-Only Antibody JM4 Efficiently Blocks both Cell-Free and T Cell-T Cell Transmission of Human Immunodeficiency Virus Type 1.

    Science.gov (United States)

    Liu, Lihong; Wang, Weiming; Matz, Julie; Ye, Chaobaihui; Bracq, Lucie; Delon, Jerome; Kimata, Jason T; Chen, Zhiwei; Benichou, Serge; Zhou, Paul

    2016-12-01

    The variable regions (VHHs) of two heavy chain-only antibodies, JM2 and JM4, from llamas that have been immunized with a trimeric gp140 bound to a CD4 mimic have been recently isolated (here referred to as VHH JM2 and VHH JM4, respectively). JM2 binds the CD4-binding site of gp120 and neutralizes HIV-1 strains from subtypes B, C, and G. JM4 binds gp120 and neutralizes HIV-1 strains from subtypes A, B, C, A/E, and G in a CD4-dependent manner. In the present study, we constructed glycosylphosphatidylinositol (GPI)-anchored VHH JM2 and JM4 along with an E4 control and transduced them into human CD4 + cell lines and primary CD4 T cells. We report that by genetically linking the VHHs with a GPI attachment signal, VHHs are targeted to the lipid rafts of the plasma membranes. Expression of GPI-VHH JM4, but not GPI-VHH E4 and JM2, on the surface of transduced TZM.bl cells potently neutralizes multiple subtypes of HIV-1 isolates, including tier 2 or 3 strains, transmitted founders, quasispecies, and soluble single domain antibody (sdAb) JM4-resistant viruses. Moreover, transduction of CEMss-CCR5 cells with GPI-VHH JM4, but not with GPI-VHH E4, confers resistance to both cell-free and T cell-T cell transmission of HIV-1 and HIV-1 envelope-mediated fusion. Finally, GPI-VHH JM4-transduced human primary CD4 T cells efficiently resist both cell-free and T cell-T cell transmission of HIV-1. Thus, we conclude that VHH JM4, when targeted to the lipid rafts of the plasma membrane, efficiently neutralizes HIV-1 infection via both cell-free and T cell-T cell transmission. Our findings should have important implications for GPI-anchored antibody-based therapy against HIV-1. Lipid rafts are specialized dynamic microdomains of the plasma membrane and have been shown to be gateways for HIV-1 budding as well as entry into T cells and macrophages. In nature, many glycosylphosphatidylinositol (GPI)-anchored proteins localize in the lipid rafts. In the present study, we developed GPI

  11. Algebraic formulas for some nontrivial U/sub n/ 6j symbols and U/sub m/n contains U/sub m/ x U/sub n/ 3jm symbols

    International Nuclear Information System (INIS)

    Haase, R.W.; Butler, P.H.

    1985-01-01

    We give tables of algebraic formulas for some nontrivial 6j symbols and 3jm symbols of the unitary groups. The tables demonstrate that the building-up method can be used successfully to obtain the rank dependence of unitary group j and jm symbols. To emphasize the rank-dependent nature of this calculation, we have employed the composite Young tableaux notation (or back-to-back notation) to label the unitary group irreps. In using this notation, the transpose conjugate symmetry of the corresponding composite Young diagram leads to a new symmetry of the unitary group 6j and 3jm symbols. The transposition of the groups U/sub m/ and U/sub n/ gives rise to a further symmetry of the 3jm symbols of U/sub m/n contains U/sub m/ x U/sub n/

  12. The HER4 isoform JM-a/CYT2 relates to improved survival in bladder cancer patients but only if the estrogen receptor α is not expressed

    DEFF Research Database (Denmark)

    Munk, Mathias; Memon, Ashfaque Ahmed; Poulsen, Steen Seier

    2013-01-01

    Abstract Bladder cancer tumors expressing human epidermal growth factor receptor 4 (HER4) demonstrate improved patient survival. HER4 isoforms and estrogen receptor alpha (ER-α) can form chaperone complexes causing cell-proliferation. We wanted to explore if HER4 isoforms and ER-α could correlate...... to poor prognosis in bladder cancers. We developed mRNA assays for HER4 isoforms (JM-a, JM-b, CYT1, and CYT2) and for ER-α. Expression was analyzed in tumors from 85 bladder cancer patients and compared to overall survival (median follow-up of 5.1 years). ER-α was expressed in 38% (n = 32) of tumors...... and half of those (18/36) expressed both isoforms. JM-a/CYT2 expression correlated to improved survival (p = 0.004), but not when ER-α was co-expressed (p = 0.897). Immunohistochemistry revealed protein expression of HER4 and ER-α in tumor cells. Growth of RT4 bladder cancer cells, expressing both JM...

  13. Phase II study of oral platinum drug JM216 as first-line treatment in patients with small-cell long cancer

    NARCIS (Netherlands)

    Fokkema, E; Groen, HJM; Uges, DRA; Weil, C; Smith, IE

    1999-01-01

    Purpose: This multicenter phase II trial wets performed to determine tumor efficacy and tolerance of the oral platinum drug JM216 in patients with small-cell lung cancer (SCLC). Patients and Methods: patients with SCLC limited disease unfit for intensive chemotherapy or those with extensive disease

  14. Symmetric group: Algebraic formulas for some S/sub f/ 6j symbols and S/sub f/containsS/sub f/1 x S/sub f/2 3jm symbols

    International Nuclear Information System (INIS)

    Haase, R.W.; Dirl, R.

    1986-01-01

    Explicit rank-dependent expressions have been obtained for some symmetric group (S/sub f/) 6j symbols and some S/sub f/containsS/sub f/ 1 x S/sub f/ 2 3jm symbols using Butler's recursion method. A key point in deriving these results is the use of the reduced notation introduced by Murnaghan to label irreps. Various symmetries of the 6j and 3jm symbols have been imposed. These include the complex conjugation, permutation, and transpose conjugation. We incorporate a new symmetry that arises from the occurrence of the two isomorphic direct product groups S/sub f/ 1 x S/sub f/ 2 and S/sub f/ 2 x S/sub f/ 1 as subgroups of S/sub f/. In relation to the tables of 6j and 3jm symbols presented, a discussion is given of the symmetric group-unitary group duality

  15. Behavior of pre-irradiated fuel under a simulated RIA condition. Results of NSRR Test JM-5

    International Nuclear Information System (INIS)

    Fuketa, Toyoshi; Sasajima, Hideo; Mori, Yukihide; Tanzawa, Sadamitsu; Ishijima, Kiyomi; Kobayashi, Shinsho; Kamata, Hiroshi; Homma, Kozo; Sakai, Haruyuki.

    1995-11-01

    This report presents results from the power burst experiment with pre-irradiated fuel rod, Test JM-5, conducted in the Nuclear Safety Research Reactor (NSRR). The data concerning test method, pre-irradiation, pre-pulse fuel examination, pulse irradiation, transient records and post-pulse fuel examination are described, and interpretations and discussions of the results are presented. Preceding to the pulse irradiation in the NSRR, test fuel rod was irradiated in the Japan Materials Testing Reactor (JMTR) up to a fuel burnup of 25.7 MWd/kgU with average linear heat rate of 33.4 kW/m. The fuel rod was subjected to the pulse irradiation resulting in a desposited energy of 223 ± 7 cal/g·fuel (0.93 ± 0.03 kJ/g·fuel) and a peak fuel enthalpy of 167 ± 5 cal/g·fuel (0.70 ± 0.02 kJ/g·fuel) under stagnant water cooling condition at atmospheric pressure and ambient temperature. Test fuel rod behavior was assessed from pre- and post-pulse fuel examinations and transient records during the pulse. The Test JM-5 resulted in cladding failure. More than twenty small cracks were found in the post-test cladding, and most of the defects located in pre-existing locally hydrided region. The result indicates an occurrence of fuel failure by PCMI (pellet/cladding mechanical interaction) in combination with decreased integrity of hydrided cladding. (author)

  16. Structure of the polysaccharides from the lipopolysaccharide of Azospirillum brasilense Jm125A2.

    Science.gov (United States)

    Sigida, Elena N; Fedonenko, Yuliya P; Shashkov, Alexander S; Zdorovenko, Evelina L; Konnova, Svetlana A; Ignatov, Vladimir V; Knirel, Yuriy A

    2015-10-30

    Two polysaccharides were obtained by mild acid degradation of the lipopolysaccharide of associative nitrogen-fixing bacteria Azospirillum brasilense Jm125A2 isolated from the rhizosphere of a pearl millet. The following structures of the polysaccharides were established by sugar and methylation analyses, Smith degradation, and (1)H and (13)C NMR spectroscopy: [Formula: see text] Structure 1 has been reported earlier for a polysaccharide from A. brasilense S17 (Fedonenko YP, Konnova ON, Zdorovenko EL, Konnova SA, Zatonsky GV, Shaskov AS, Ignatov VV, Knirel YA. Carbohydr Res 2008;343:810-6), whereas to our knowledge structure 2 has not been hitherto found in bacterial polysaccharides. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. An advanced modelling tool for simulating complex river systems.

    Science.gov (United States)

    Trancoso, Ana Rosa; Braunschweig, Frank; Chambel Leitão, Pedro; Obermann, Matthias; Neves, Ramiro

    2009-04-01

    The present paper describes MOHID River Network (MRN), a 1D hydrodynamic model for river networks as part of MOHID Water Modelling System, which is a modular system for the simulation of water bodies (hydrodynamics and water constituents). MRN is capable of simulating water quality in the aquatic and benthic phase and its development was especially focused on the reproduction of processes occurring in temporary river networks (flush events, pools formation, and transmission losses). Further, unlike many other models, it allows the quantification of settled materials at the channel bed also over periods when the river falls dry. These features are very important to secure mass conservation in highly varying flows of temporary rivers. The water quality models existing in MOHID are base on well-known ecological models, such as WASP and ERSEM, the latter allowing explicit parameterization of C, N, P, Si, and O cycles. MRN can be coupled to the basin model, MOHID Land, with computes runoff and porous media transport, allowing for the dynamic exchange of water and materials between the river and surroundings, or it can be used as a standalone model, receiving discharges at any specified nodes (ASCII files of time series with arbitrary time step). These features account for spatial gradients in precipitation which can be significant in Mediterranean-like basins. An interface has been already developed for SWAT basin model.

  18. Studies on cellular accumulation of satraplatin and its major metabolite JM118 and their interactions with glutathione

    Czech Academy of Sciences Publication Activity Database

    Kostrhunová, Hana; Kašpárková, Jana; Gibson, D.; Brabec, Viktor

    2010-01-01

    Roč. 7, č. 6 (2010), s. 2093-2102 ISSN 1543-8384 R&D Projects: GA MŠk(CZ) ME08017; GA MŠk(CZ) ME10066; GA MŠk(CZ) OC08003; GA AV ČR(CZ) IAA400040803; GA ČR(CZ) GAP301/10/0598 Grant - others:GA MŠk(CZ) LC06030; GA AV ČR(CZ) KAN200200651 Program:LC; KA Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702 Keywords : JM118 * cellular accumulation * glutathione Subject RIV: BO - Biophysics Impact factor: 5.400, year: 2010

  19. Draft genome sequence of Bacillus thuringiensis strain BrMgv02-JM63, a chitinolytic bacterium isolated from oil-contaminated mangrove soil in Brazil

    NARCIS (Netherlands)

    Marcon, Joelma; Taketani, Rodrigo Gouvêa; Dini-Andreote, Francisco; Mazzero, Giulia Inocêncio; Soares Junior, Fabio Lino; Melo, Itamar Soares; Azevedo, João Lúcio; Andreote, Fernando Dini

    2014-01-01

    Here, we report the draft genome sequence and the automatic annotation of Bacillus thuringiensis strain BrMgv02-JM63. This genome comprises a set of genes involved in the metabolism of chitin and N-acetylglucosamine utilization, thus suggesting the possible role of this strain in the cycling of

  20. Interpreting map art with a perspective learned from J.M. Blaut

    Science.gov (United States)

    Varanka, D.

    2006-01-01

    Map art has been mentioned only briefly in geographic or cartographic literature, and has been analyzed almost entirely at the interpretive level. This paper attempts to define and evaluate the cartographic value of contemporary map-like art by placing the body of work as a whole in the theoretical concepts proposed by J.M. Blaut and his colleagues about mapping as a cognitive and cultural universal. This paper discusses how map art resembles mapping characteristics similar to those observed empirically in very young children as described in the publications of Blaut and others. The theory proposes that these early mapping skills are later structured and refined by their social context and practice. Diverse cultural contexts account for the varieties, types, and degrees of mapping behavior documented with time and geographic place. The dynamics of early mapping are compared to mapping techniques employed by artists. The discipline of fine art serves as the context surrounding map artists and their work. My visual analysis, research about the art and the artists, and interviews with artists and curators form the basis of my interpretation of these works within varied and multiple contexts of late 20th century map art.

  1. Mobile Fences: J.M. Coetzee’s Waiting for the Barbarians

    Directory of Open Access Journals (Sweden)

    Eleonora Pizzinat

    2011-05-01

    Full Text Available Fences usually enclose and separate, but they are also places of exchange neither inside nor outside. This concept is well represented in J.M. Coetzee’s Waiting for the Barbarians, because not only this novel is setted on the border between an undefined Empire and the barbarians’ lands, but it also plays with various declinations of the idea of limit and boundary. Through a reading which intends to highlight every kind of frame in the novel, it will emerge that no border is fixed and conclusive. Namely, in this book every real or metaphoric fence is called into question: the distinction between the duality of “us and them” is actually determined by the Empire’s walls which separate the inside from the outside in an arbitrary way; the magistrate (with the empathy he feels for the barbarian girl is inevitably caught in a double bind; and, according to Emmanuel Lévinas’ philosophy, the desire to understand otherness reveals its predatory intentions from a post-colonial point of view. It is not possible to delineate an ultimate bordeline, and it will emerge that instead of a binary logic there is a more fruitful way of thinking, a way based on frames, paradoxes and literary texts which cannot be read as flat mirroring devices.

  2. Autofiction and Fictionalisation: J.M. Coetzee’s Novels and Boyhood

    Directory of Open Access Journals (Sweden)

    Shadi Neimneh

    2015-05-01

    Full Text Available This article tackles the issue of autobiography or self-representation in J.M. Coetzee's fictionalised memoir Boyhood in terms of the useful insights of fictionalised autobiographies to the study of fictional ones by the same author. I seek to resolve the tension between fiction and autobiography in the aforementioned works. My goal is showing how a fictionalised memoir with autobiographical value like Boyhood is a helpful tool for understanding and engaging Coetzee’s other fictions. Therefore, and using textual evidence, I draw parallels between Boyhood and other representative novels from Coetzee’s oeuvre like Life and Times of Michael K, Disgrace, and Waiting for the Barbarians. Among the intertextual clues I discuss are notions like desire/the body, animals, and farm life. The study concludes by recommending an intra-comparative approach to Coetzee’s works whereby we gain so much by juxtaposing one Coetzee work against another in a process of mirroring or doubling. This article is significant because it elaborates an intertextual model for reading Coetzee’s fictionalised autobiographies and ‘autobiographical’ novels against each other, and away from the muddle of existing theory and Coetzee criticism. The autobiographical value of Coetzee’s fiction is worth analysis, and genre distinctions between autobiographies disguised/fictionalised as novels (autofictions and novels with autobiographical import are flimsy.

  3. Dis/Graceful Liberties: Textual Libertinism/ Libertine Texts in J.M. Coetzee’s Disgrace

    Directory of Open Access Journals (Sweden)

    Driss Hager Ben

    2017-12-01

    Full Text Available This essay addresses J.M. Coetzee’s Disgrace, a Booker Prize winner in 1999. The novel captures South African political and cultural turmoil attending the post-apartheid transitional period. Far from overlooking the political allegory, I propose instead to expand on a topic only cursorily developed elsewhere, namely liberty and license. The two terms foreground the textual dynamics of the novel as they compete and/or negotiate meaning and ascendency. I argue that Disgrace is energized by Coetzee’s belief in a total liberty of artistic production. Sex is philosophically problematized in the text and advocated as a serious issue that deserves artistic investigation without restriction or censorship. This essay looks into the subtle libertinism in Coetzee’s text, which displays pornographic overtones without exhibiting a flamboyant libertinage. Disgrace acquires its libertine gesture from its dialogue with several literary works steeped in libertinism. The troubled relationship between the aesthetic and the ethical yields an ambiguous text that invites a responsible act of reading.

  4. Draft Genome Sequence of Bacillus thuringiensis Strain BrMgv02-JM63, a Chitinolytic Bacterium Isolated from Oil-Contaminated Mangrove Soil in Brazil.

    Science.gov (United States)

    Marcon, Joelma; Taketani, Rodrigo Gouvêa; Dini-Andreote, Francisco; Mazzero, Giulia Inocêncio; Soares, Fabio Lino; Melo, Itamar Soares; Azevedo, João Lúcio; Andreote, Fernando Dini

    2014-01-30

    Here, we report the draft genome sequence and the automatic annotation of Bacillus thuringiensis strain BrMgv02-JM63. This genome comprises a set of genes involved in the metabolism of chitin and N-acetylglucosamine utilization, thus suggesting the possible role of this strain in the cycling of organic matter in mangrove soils.

  5. [Efficacy of frequency-neurofeedback and Cogmed JM-working memory training in children with ADHD].

    Science.gov (United States)

    van Dongen-Boomsma, M; Vollebregt, M A; Slaats-Willemse, D; Buitelaar, J K

    2015-01-01

    The need for and the interest in non-pharmacological treatments for children with ADHD are increasing. The treatments include electro-encephalogram (EEG) frequency-neurofeedback and Cogmed working memory training. To investigate the efficacy of frequency-neurofeedback and Cogmed working memory training in children with ADHD. Forty-one children with ADHD (aged 8-15 years) were assigned to frequency-neurofeedback or to placebo-neurofeedback in a randomized double-blind trial. We took measurements to find out whether frequency-neurofeedback had reduced the severity of the ADHD-symptoms, and/or had improved neurocognitive ability and global clinical functioning. Fifty-one children with ADHD (aged 5-7 years) were assigned to the active Cogmed JM-working memory training or to the placebo working memory training in a randomised double-blind trial. We took measurements to find out whether Cogmed JM-working memory training had reduced the ADHD symptoms, and/or had improved neurocognitive ability, daily performance and global clinical functioning. The ADHD symptoms and global clinical functioning of the children in both neurofeedback groups improved. However, frequency-neurofeedback did nor produce any significantly better treatment results than did the placebo neurofeedback. At the neurocognitive level, frequency-neurofeedback did not yield any measurements that were significantly superior to those achieved with placebo feedback. Various outcome measurements improved in both groups with memory training. However, the active working memory training was not found to have produced significantly better results than the placebo training with regards to the ADHD symptoms, neurocognitive ability and daily and global functioning. Children from the active working memory training group showed improvements in trained working memory tasks but not on untrained tasks. Neither study produced any conclusive evidence for the efficacy of the investigated treatments in children with ADHD

  6. Bioaugmentation on decolorization of C.I. Direct Blue 71 by using genetically engineered strain Escherichia coli JM109 (pGEX-AZR)

    International Nuclear Information System (INIS)

    Jin Ruofei; Yang Hua; Zhang Aili; Wang Jing; Liu Guangfei

    2009-01-01

    The study showed that Escherichia coli JM109 (pGEX-AZR), the genetically engineered microorganism (GEM) with higher ability to decolorize azo dyes, bioaugmented successfully the dye wastewater bio-treatment systems to enhance C.I. Direct Blue 71 (DB 71) decolorization. The control and bioaugmented reactors failed at a around pH 5.0. However, the bioaugmented one succeeded at around pH 9.0, the influent DB 71 concentration was 150 mg/L, DB 71 concentration was decreased to 27.4 mg/L in 12 h. The 1-3% NaCl concentration of bioaugmented reactors had no definite influence on decolorization, DB 71 concentration was decreased to 12.6 mg/L in 12 h. GEM was added into anaerobic sequencing batch reactors (AnSBRs) to enhance DB 71 decolorization. Continuous operations of the control and bioaugmented AnSBRs showed that E. coli JM109 (pGEX-AZR) could bioaugment decolorization. The concentrations of activated sludge and GEM were still more than 2.80 g/L and 1.5 x 10 6 cells/mL, respectively, in the bioaugmented AnSBR. All the microbial communities changed indistinctively with time. The microbial community structures of the control AnSBR were similar to those of the bioaugmented one

  7. Bioaugmentation on decolorization of C.I. Direct Blue 71 by using genetically engineered strain Escherichia coli JM109 (pGEX-AZR)

    Energy Technology Data Exchange (ETDEWEB)

    Jin Ruofei; Yang Hua; Zhang Aili; Wang Jing [School of Environmental and Biological Science and Technology, Dalian University of Technology, Dalian 116023 (China); Liu Guangfei [School of Environmental and Biological Science and Technology, Dalian University of Technology, Dalian 116023 (China)], E-mail: guangfeiliu@yahoo.com.cn

    2009-04-30

    The study showed that Escherichia coli JM109 (pGEX-AZR), the genetically engineered microorganism (GEM) with higher ability to decolorize azo dyes, bioaugmented successfully the dye wastewater bio-treatment systems to enhance C.I. Direct Blue 71 (DB 71) decolorization. The control and bioaugmented reactors failed at a around pH 5.0. However, the bioaugmented one succeeded at around pH 9.0, the influent DB 71 concentration was 150 mg/L, DB 71 concentration was decreased to 27.4 mg/L in 12 h. The 1-3% NaCl concentration of bioaugmented reactors had no definite influence on decolorization, DB 71 concentration was decreased to 12.6 mg/L in 12 h. GEM was added into anaerobic sequencing batch reactors (AnSBRs) to enhance DB 71 decolorization. Continuous operations of the control and bioaugmented AnSBRs showed that E. coli JM109 (pGEX-AZR) could bioaugment decolorization. The concentrations of activated sludge and GEM were still more than 2.80 g/L and 1.5 x 10{sup 6} cells/mL, respectively, in the bioaugmented AnSBR. All the microbial communities changed indistinctively with time. The microbial community structures of the control AnSBR were similar to those of the bioaugmented one.

  8. Glucose uptake regulation in E. coli by the small RNA SgrS: comparative analysis of E. coli K-12 (JM109 and MG1655 and E. coli B (BL21

    Directory of Open Access Journals (Sweden)

    Ng Weng-Ian

    2010-09-01

    Full Text Available Abstract Background The effect of high glucose concentration on the transcription levels of the small RNA SgrS and the messenger RNA ptsG, (encoding the glucose transporter IICBGlc, was studied in both E. coli K-12 (MG1655 and JM109 and E. coli B (BL21. It is known that the transcription level of sgrS increases when E. coli K-12 (MG1655 and JM109 is exposed to the non-metabolized glucose alpha methyl glucoside (αMG or when the bacteria with a defective glycolysis pathway is grown in presence of glucose. The increased level of sRNA SgrS reduces the level of the ptsG mRNA and consequently lowers the level of the glucose transporter IICBGlc. The suggested trigger for this action is the accumulation of the corresponding phospho-sugars. Results In the course of the described work, it was found that E. coli B (BL21 and E. coli K-12 (JM109 and MG1655 responded similarly to αMG: both strains increased SgrS transcription and reduced ptsG transcription. However, the two strains reacted differently to high glucose concentration (40 g/L. E. coli B (BL21 reacted by increasing sgrS transcription and reducing ptsG transcription while E. coli K-12 (JM109 and MG1655 did not respond to the high glucose concentration, and, therefore, transcription of sgrS was not detected and ptsG mRNA level was not affected. Conclusions The results suggest that E. coli B (BL21 tolerates high glucose concentration not only by its more efficient central carbon metabolism, but also by controlling the glucose transport into the cells regulated by the sRNA SgrS, which may suggest a way to control glucose consumption and increase its efficient utilization.

  9. Na2 Vibrating in the Double-Well Potential of State 2 1Σu+ (JM = 00): A Pulsating "Quantum Bubble" with Antagonistic Electronic Flux.

    Science.gov (United States)

    Diestler, D J; Jia, D; Manz, J; Yang, Y

    2018-03-01

    The theory of concerted electronic and nuclear flux densities associated with the vibration and dissociation of a multielectron nonrotating homonuclear diatomic molecule (or ion) in an electronic state 2S+1 Σ g,u + (JM = 00) is presented. The electronic population density, nuclear probability density, and nuclear flux density are isotropic. A theorem of Barth , presented in this issue, shows that the electronic flux density (EFD) is also isotropic. Hence, the evolving system appears as a pulsating, or exploding, "quantum bubble". Application of the theory to Na 2 vibrating in the double-minimum potential of the 2   1 Σ u + (JM = 00) excited state reveals that the EFD consists of two antagonistic components. One arises from electrons that flow essentially coherently with the nuclei. The other, which is oppositely directed (i.e., antagonistic) and more intense, is due to the transition in electronic structure from "Rydberg" to "ionic" type as the nuclei traverse the potential barrier between inner and outer potential wells. This "transition" component of the EFD rises and falls sharply as the nuclei cross the barrier.

  10. Selection of Co-Substrate and Aeration Conditions for Vanillin Production by Escherichia coli JM109/pBB1

    Directory of Open Access Journals (Sweden)

    Paolo Torre

    2004-01-01

    Full Text Available Yeast extract, Luria-Bertani medium and tryptone were tested as co-substrates for vanillin production from ferulic acid by resting cells of Escherichia coli JM109/pBB1. Yeast extract proved to be the best component for sustaining such a bioconversion, which is not self-sustained from the bioenergetic point of view. Tests were also performed under variable aeration conditions by simultaneously varying the ratio of medium to vessel volume and the agitation speed. The results of these tests suggest that, under excess aeration, a non-specific oxidase activity was very likely responsible for the oxidation of a significant portion of vanillin to vanillic acid, thus reducing the vanillin yield.

  11. Mirror Neurons and Literature: Empathy and the Sympathetic Imagination in the Fiction of J.M. Coetzee

    Directory of Open Access Journals (Sweden)

    Hilmar Heister

    2015-01-01

    Full Text Available In the two essays “The Philosophers and the Animals” and “The Poets and the Animals” (in The Lives of Animals, 1999 J.M. Coetzee lets Elizabeth Costello urge us to use our sympathetic imagination in order to access the experience of others—in particular, animals—and engage with them empathetically. Coetzee’s fiction illustrates how the use of the sympathetic imagination might evoke empathy in the reader. Narrative structure and the character’s mode of introspection engage the reader’s empathy through an ambivalent process of distancing and approximation, as Fritz Breithaupt puts forward in his narrative theory of empathy (Kulturen der Empathie, 2009. The sympathetic imagination and the complementary notion of embodiment feature prominently in Coetzee’s fictional discourse and resonate with neuroscience’s research on mirror neurons and their relation to empathy.

  12. Media, a President, and His Generals: How the Media Shaped Civil-Military Relations during the Mexican War

    Science.gov (United States)

    2011-05-19

    comparison and contrast of President Polk’s treatment of General Winfield Scott and General Zachary Taylor. Finally, part 3 offers a review of relevant...enjoyed farming and life in the great wilderness. General Zachary Taylor: “Old Rough and Ready” 29 Often clad in leather moccasins, blue pants, and...made their way into news headlines, it ignited a powder keg of political gossip in the press. 212

  13. Evolution of ocean-induced ice melt beneath Zachariæ Isstrøm, Northeast Greenland combining observations and an ocean general circulation model from 1978 to present

    Science.gov (United States)

    Cai, C.; Rignot, E. J.; Menemenlis, D.; Millan, R.; Bjørk, A. A.; Khan, S. A.; Charolais, A.

    2017-12-01

    Zachariæ Isstrøm, a major ice stream in northeast Greenland, lost a large fraction of its ice shelf during the last decade. We study the evolution of subaqueous melting of its floating section from 1978 to present. The ice shelf melt rate depends on thermal forcing from warm, salty, subsurface ocean waters of Atlantic origin (AW), the mixing of AW with fresh, buoyant subglacial discharge at the calving margin, and the shape of the sub-ice-shelf cavity. Subglacial discharge doubled as a result of enhanced ice sheet runoff caused by warmer air temperatures. Ocean thermal forcing has increased due to enhanced advection of AW. Using an Eulerian method, MEaSUREs ice velocity, Operation IceBridge (OIB) ice thickness, and RACMO2.3 surface balance data, we evaluate the ice shelf melt rate in 1978, 1999 and 2010. The melt rate doubled from 1999 to 2010. Using a Lagrangian method with World View imagery, we map the melt rate in detail from 2011 to 2016. We compare the results with 2D simulations from the Massachusetts Institute of Technology general circulation model (MITgcm), at a high spatial resolution (20-m horizontal and 40-m vertical grid spacing), using OIB ice thickness and sub-ice-shelf cavity for years 1978, 1996, 2010 and 2011, combined with in-situ ocean temperature/salinity data from Ocean Melting Greenland (OMG) 2017. We find that winter melt rates are 2 3 times smaller than summer rates and melt rates increase by one order magnitude during the transition from ice shelf termination to near-vertical calving wall termination. As the last remaining bits of floating ice shelf disappear, ice-ocean interaction will therefore play an increasing role in driving the glacier retreat into its marine-based basin. This work was performed under a contract with NASA Cryosphere Program at UC Irvine and Caltech's Jet Propulsion Laboratory.

  14. A watershed model to integrate EO data

    Science.gov (United States)

    Jauch, Eduardo; Chambel-Leitao, Pedro; Carina, Almeida; Brito, David; Cherif, Ines; Alexandridis, Thomas; Neves, Ramiro

    2013-04-01

    MOHID LAND is a open source watershed model developed by MARETEC and is part of the MOHID Framework. It integrates four mediums (or compartments): porous media, surface, rivers and atmosphere. The movement of water between these mediums are based on mass and momentum balance equations. The atmosphere medium is not explicity simulated. Instead, it's used as boundary condition to the model through meteorological properties: precipitation, solar radiation, wind speed/direction, relative humidity and air temperature. The surface medium includes the overland runoff and vegetation growth processes and is simulated using a 2D grid. The porous media includes both the unsaturated (soil) and saturated zones (aquifer) and is simulated using a 3D grid. The river flow is simulated through a 1D drainage network. All these mediums are linked through evapotranspiration and flow exchanges (infiltration, river-soil growndwater flow, surface-river overland flow). Besides the water movement, it is also possible to simulate water quality processes and solute/sediment transport. Model setup include the definition of the geometry and the properties of each one of its compartments. After the setup of the model, the only continuous input data that MOHID LAND requires are the atmosphere properties (boundary conditions) that can be provided as timeseries or spacial data. MOHID LAND has been adapted the last 4 years under FP7 and ESA projects to integrate Earth Observation (EO) data, both variable in time and in space. EO data can be used to calibrate/validate or as input/assimilation data to the model. The currently EO data used include LULC (Land Use Land Cover) maps, LAI (Leaf Area Index) maps, EVTP (Evapotranspiration) maps and SWC (Soil Water Content) maps. Model results are improved by the EO data, but the advantage of this integration is that the model can still run without the EO data. This means that model do not stop due to unavailability of EO data and can run on a forecast mode

  15. Cultivo in vitro de Schinus fasciculata (Griseb J.M. Johnst var. fasciculata (molle

    Directory of Open Access Journals (Sweden)

    Claudia Alzugaray

    2014-07-01

    Full Text Available Título en español: Cultivo in vitro de Schinus fasciculata (Griseb J.M. Johnst var. fasciculata (molle Título en ingles: In vitro culture of Schinus fasciculata (Griseb J.M. Johnst var. fasciculata (molle Resumen: Schinus fasciculata es un árbol de la ecorregión chaqueña argentina. Es una especie de bajo porte, usada como antiséptico, analgésico, antiinflamatorio y antifúngico. Estudios previos registraron baja germinación y deficiente sanidad. El objetivo fue evaluar la germinación y la respuesta de las plántulas in vitro en dos medios de cultivo. Se recolectaron frutos, se desinfectaron por 20 min con HClNa y se sembraron en agar-agua. Las plántulas se repicaron a medio MS en dos diluciones: un cuarto (MS ¼ y un medio (MS ½. Se hicieron ensayos de germinación y vigor (tiempo medio de germinación máxima en días. Se evaluó % de contaminación. A los 20 días del repique se evaluó % de explantos con hojas, número de hojas y altura de plántulas. Paralelamente se hizo un ensayo de germinación y vigor en arena. La contaminación fue de 16 %, la germinación de 84 %, el vigor de 4,9 días. El 94 y el 100 % de los explantos en MS ¼ y MS ½ presentaron hojas. El número promedio de hojas fue de 7,5 y 7,4 y la altura promedio fue de 3,35 cm y 2,98 cm en MS ¼ y MS ½, observándose diferencias significativas en altura. La germinación en arena fue de 46 % y el  vigor de 4,6 días. La utilización de la técnica de cultivo in vitro en S. fasciculata facilita la multiplicación de esta especie de alto valor farmacológico, permitiendo aumentar el porcentaje de frutos germinados y obtener plántulas libres de patógenos todo el año.  Palabras clave: Schinus fasciculata, germinación, vigor, cultivo in vitro.  Abstract:  Schinus fasciculata is a tree of Argentina Chaco eco-region. It is a low-growing species, used as an antiseptic, analgesic, anti-inflammatory and antifungal. Previous studies reported low germination and poor

  16. Subverting the pastoral: the transcendence of space and place in J.M. Coetzee’s Disgrace

    Directory of Open Access Journals (Sweden)

    S. Smit-Marais

    2006-07-01

    Full Text Available This article investigates how J.M. Coetzee’s “Disgrace” (1999 – portrayed as a postcolonial and postmodern fictional event – embodies, problematises and subverts the vision of the pastoral farm novel tradition by transcending traditional configurations of space and place. The novel offers a rather bleak apocalyptic vision of gender roles, racial relationships and family relations in post-apartheid South Africa and expresses the socio-political tensions pertaining to the South African landscape in terms of personal relationships. As a fictional reworking of the farm novel, “Disgrace” draws on the tradition’s anxieties about the rights of (white ownership, but within a post-apartheid context. As such, “Disgrace” challenges the pastoral farm novel’s “dream topography” (Coetzee, 1988:6 of the family farm ruled by the patriarch – a topography inscribed – with the help of the invisible labour of black hands – as a legacy of power and ownership to be inherited and cultivated in perpetuity. Accordingly, the concept “farm” is portrayed as a contested and liminal space inscribed with a history of violence and dispossession – a dystopia. This article therefore conceptualises “Disgrace” as an antipastoral farm novel that reconfigures the concept “farm” – within the context of the South African reality – by subverting, inverting and parodying the structures of space and place postulated by the pastoral farm novel.

  17. Modelling of sediment transport and morphological evolution under the combined action of waves and currents

    Science.gov (United States)

    Franz, Guilherme; Delpey, Matthias T.; Brito, David; Pinto, Lígia; Leitão, Paulo; Neves, Ramiro

    2017-09-01

    Coastal defence structures are often constructed to prevent beach erosion. However, poorly designed structures may cause serious erosion problems in the downdrift direction. Morphological models are useful tools to predict such impacts and assess the efficiency of defence structures for different scenarios. Nevertheless, morphological modelling is still a topic under intense research effort. The processes simulated by a morphological model depend on model complexity. For instance, undertow currents are neglected in coastal area models (2DH), which is a limitation for simulating the evolution of beach profiles for long periods. Model limitations are generally overcome by predefining invariant equilibrium profiles that are allowed to shift offshore or onshore. A more flexible approach is described in this paper, which can be generalised to 3-D models. The present work is based on the coupling of the MOHID modelling system and the SWAN wave model. The impacts of different designs of detached breakwaters and groynes were simulated in a schematic beach configuration following a 2DH approach. The results of bathymetry evolution are in agreement with the patterns found in the literature for several existing structures. The model was also tested in a 3-D test case to simulate the formation of sandbars by undertow currents. The findings of this work confirmed the applicability of the MOHID modelling system to study sediment transport and morphological changes in coastal zones under the combined action of waves and currents. The same modelling methodology was applied to a coastal zone (Costa da Caparica) located at the mouth of a mesotidal estuary (Tagus Estuary, Portugal) to evaluate the hydrodynamics and sediment transport both in calm water conditions and during events of highly energetic waves. The MOHID code is available in the GitHub repository.

  18. An Integrated Management System (IMS) for JM-1 SLOWPOKE-2 research reactor in Jamaica: experiences in documentation

    International Nuclear Information System (INIS)

    Warner, T.

    2014-01-01

    Since the first criticality in March 1984, the Jamaica SLOWPOKE-2 research reactor at the University of the West Indies, Mona located in the department of the International Centre for Environmental and Nuclear Sciences (ICENS) has operated for approximately 52% of the lifetime of the existing core configuration. The 20kW pool type research reactor has been primarily used for neutron activation analysis in environmental, agricultural, geochemical, health-related studies and mineral exploration in Jamaica. The involvement of the JM-1 reactor for research and teaching activities has segued into commercial applications which, coupled with the current core conversion programme from HEU to LEU, has demanded the implementation of management systems to satisfy regulatory requirements and assure compliance with internationally defined quality standards. At ICENS, documentation related to the Quality Management System aspect of an Integrated Management System (IMS) is well underway. The quality system will incorporate operational and nuclear safety, training, maintenance, design, utilization, occupational health and safety, quality service, and environmental management for its Nuclear Analytical Laboratory, NAL. The IMS is being designed to meet the requirements of the IAEA GS-R-3 with additional controls from international standards including: ISO/IEC 17025:2005, ISO 9001:2008, ISO 14001:2004 and OHSAS 18001:2007. This paper reports on the experiences of the documentation process in a low power reactor facility characterized by limited human resource, where innovative mechanisms of system automation and modeling are included to increase productivity and efficiency. (author)

  19. An Integrated Management System (IMS) for JM-1 SLOWPOKE-2 research reactor in Jamaica: experiences in documentation

    Energy Technology Data Exchange (ETDEWEB)

    Warner, T., E-mail: traceyann.warner02@uwimona.edu.jm [Univ. of West Indies, Mona (Jamaica)

    2014-07-01

    Since the first criticality in March 1984, the Jamaica SLOWPOKE-2 research reactor at the University of the West Indies, Mona located in the department of the International Centre for Environmental and Nuclear Sciences (ICENS) has operated for approximately 52% of the lifetime of the existing core configuration. The 20kW pool type research reactor has been primarily used for neutron activation analysis in environmental, agricultural, geochemical, health-related studies and mineral exploration in Jamaica. The involvement of the JM-1 reactor for research and teaching activities has segued into commercial applications which, coupled with the current core conversion programme from HEU to LEU, has demanded the implementation of management systems to satisfy regulatory requirements and assure compliance with internationally defined quality standards. At ICENS, documentation related to the Quality Management System aspect of an Integrated Management System (IMS) is well underway. The quality system will incorporate operational and nuclear safety, training, maintenance, design, utilization, occupational health and safety, quality service, and environmental management for its Nuclear Analytical Laboratory, NAL. The IMS is being designed to meet the requirements of the IAEA GS-R-3 with additional controls from international standards including: ISO/IEC 17025:2005, ISO 9001:2008, ISO 14001:2004 and OHSAS 18001:2007. This paper reports on the experiences of the documentation process in a low power reactor facility characterized by limited human resource, where innovative mechanisms of system automation and modeling are included to increase productivity and efficiency. (author)

  20. City Limits, 2004, East Baton Rouge Parish, Louisiana

    Data.gov (United States)

    Louisiana Geographic Information Center — This is a graphical polygon dataset depicting the polygon boundaries of the incorporated city limits of Baton Rouge, Baker, and Zachary within East Baton Rouge...

  1. As, Bi, Hg, S, Sb, Sn and Te geochemistry of the J-M Reef, Stillwater Complex, Montana: constraints on the origin of PGE-enriched sulfides in layered intrusions

    Science.gov (United States)

    Zientek, M.L.; Fries, T.L.; Vian, R.W.

    1990-01-01

    The J-M Reef is an interval of disseminated sulfides in the Lower Banded series of the Stillwater Complex that is enriched in the platinum group elements (PGE). Palladium and Pt occur in solid solution in base-metal sulfides and as discrete PGE minerals. PGE minerals include sulfides, tellurides, arsenides, antimonides, bismuthides, and alloys with Fe, Sn, Hg, and Au. Several subpopulations can be delineated based on whole-rock chemical analyses for As, Bi, Cu, Hg, Pd, Pt, S, Sb and Te for samples collected from and adjacent to the J-M Reef. In general, samples from within the reef have higher Pt/Cu, Pd/Cu, Pd/Pt, Te/Bi and S/(Te+Bi) than those collected adjacent to the reef. Vertical compositional profiles through the reef suggest that Pd/Cu and Pt/Cu decrease systematically upsection from mineralized to barren rock. The majority of samples with elevated As, Sb and Hg occur adjacent to the reef, not within it, or in sulfide-poor rocks. Neither magma mixing nor fluid migration models readily explain why the minor quantities of sulfide minerals immediately adjacent to the sulfide-enriched layers that form the J-M Reef have different element ratios than the sulfide minerals that form the reef. If all the sulfides formed by exsolution during a magma mixing event and the modal proportion of sulfide now in the rocks are simply the result of mechanical processes that concentrated the sulfides into some layers and not others, then the composition of the sulfide would not be expected to be different. Models that rely upon ascending liquids or fluids are incompatible with the presence of sulfides that are not enriched in PGE immediately below or interlayered with the PGE-enriched sulfides layers. PGE-enriched postcumulus fluids should have reacted to the same extent with sulfides immediately outside the reef as within the reef. One explanation is that some of the sulfide minerals in the rocks outside the reef have a different origin than those that make up the reef. The

  2. African Journal of Reproductive Health - Vol 18, No 3 (2014)

    African Journals Online (AJOL)

    PERSPECTIVES PAPER: Medicalization of HIV and the African Response · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. S Gitome, Stella Njuguna, Zachary Kwena, Everlyne Ombati, B Njoroge, EA Bukusi, 25-33 ...

  3. Lightweight Portable Plasma Medical Device - Plasma Engineering Research Laboratory

    Science.gov (United States)

    2012-10-01

    a wide range of standard biomedical treatment applications. The ppm concentration of NO2 is below the OSHA safety standards. The formation of...K. F. Muhammad, A. H. Ahmad, and Z. Mohid, in Experimental micromachining of silicon with Nd-YAG laser, Malaysia , 2011 (Trans Tech Publications), p...applications. The ppm concentration of NO2 is below the OSHA safety standards. The formation of different active species produced in non-thermal air

  4. 17 January 2014 - Y. Sakurada Japanese Senior Vice Minister of Education, Culture, Sports, Science and Technology signing the Guest book with CERN Director-General R. Heuer and visiting the LHC tunnel at Point 1 with Technology Department Head J.M. Jiménez. Head of International Relations R. Voss present throughout.

    CERN Multimedia

    Pantelia, Anna

    2014-01-01

    17 January 2014 - Y. Sakurada Japanese Senior Vice Minister of Education, Culture, Sports, Science and Technology signing the Guest book with CERN Director-General R. Heuer and visiting the LHC tunnel at Point 1 with Technology Department Head J.M. Jiménez. Head of International Relations R. Voss present throughout.

  5. Synthesis of a Pilot Scale Library of 4-amino-2 (diethylaminomethyl) phenol (ADOC) Analogues for Testing of Organophosphate-Inhibited Acetylcholinesterase Reactivation Ability

    Science.gov (United States)

    2018-02-01

    Inhibited Acetylcholinesterase Reactivation Ability Zachary Canter Kevin Martin Michael Hepperle February 2018 Approved for public release; distribution...PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Canter, Z., Martin , K., Hepperle, M. 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING

  6. The Role Of The Military In Myanmars Political Economy

    Science.gov (United States)

    2016-03-01

    MILITARY IN MYANMAR’S POLITICAL ECONOMY by Pamela T. Stein March 2016 Thesis Advisor: Naazneen Barma Second Reader: Zachary Shore THIS......DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words) This thesis examines the role of Myanmar’s military, the Tatmadaw, in the country’s political economy

  7. 77 FR 22786 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Science.gov (United States)

    2012-04-17

    ... May 2, 2012. A. Federal Reserve Bank of Chicago (Colette A. Fried, Assistant Vice President) 230 South...; Anne R. Sparks, John W. Sparks, and Zachary Whitten, all of Albuquerque, New Mexico; Benjamin I... Filed 4-16-12; 8:45 am] BILLING CODE 6210-01-P ...

  8. 8 April 2011 - Brazilian Minister of State for Science and Technology A. Mercadante Oliva signing the guest book with CERN Director-General R. Heuer and Head of International Relations F. Pauss; in the ATLAS visitor centre with Collaboration Former Spokesperson P. Jenni; visiting LHC superconducting magnet test hall with J.M. Jimenez.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    8 April 2011 - Brazilian Minister of State for Science and Technology A. Mercadante Oliva signing the guest book with CERN Director-General R. Heuer and Head of International Relations F. Pauss; in the ATLAS visitor centre with Collaboration Former Spokesperson P. Jenni; visiting LHC superconducting magnet test hall with J.M. Jimenez.

  9. 1 April 2014 - President of the Parliament of the Principality of Liechtenstein A. Frick and his delegation visiting the LHC tunnel at Point 1 with Technology Department Head J.M. Jiménez and signing the Guest book with CERN Director-General R. Heuer. Deputy Head of International Relations E. Tsesmelis present throughout.

    CERN Multimedia

    Pantelia, Anna

    2014-01-01

    1 April 2014 - President of the Parliament of the Principality of Liechtenstein A. Frick and his delegation visiting the LHC tunnel at Point 1 with Technology Department Head J.M. Jiménez and signing the Guest book with CERN Director-General R. Heuer. Deputy Head of International Relations E. Tsesmelis present throughout.

  10. The American Military and the Far East, Proceedings of the Ninth Military History Symposium, United States Air Force Academy, 1-3 October 1980,

    Science.gov (United States)

    1980-10-01

    movies and social dances had so permeated the country that many Chinese were influenced by the Western notion that marriage, or for that matter divorce ...34The Monterrey Campaign" of Zachary Taylor in the Mexican War.3 The nearest thing to an official history, The Philippine Insurrection Against the

  11. Civil Affairs History and Doctrine: From Military Government to Interagency Partner

    Science.gov (United States)

    2016-06-10

    88 APPENDIX E SPECIAL OPERATIONS FORCES CIVIL AFFAIRS INTERVIEW RESPONSES...cessation of combat operations. Major General Zachary Taylor’s occupation of northern Mexico, based in Vera Cruz, was...and C are examples of the questions asked of respondents, and Appendices D and E contain the interview responses themselves. The research employs

  12. Book Review: 'Digital media sport: Technology, power and culture in the network society'

    OpenAIRE

    Sturm, DC

    2014-01-01

    Book Review for Gender and genre in sports documentaries: critical essays, edited by Zachary Ingle and David M. Sutera, Plymouth, Scarecrow Press, 2013, 204 pp., US$65.00/£39.95 (hardback), ISBN 978-0-8108-8788-6, US$64.99/£39.95 (eBook), ISBN 978-0-8108-5 8787-9

  13. 76 FR 33746 - Freeport LNG Development, L.P.; Application for Blanket Authorization To Export Liquefied Natural...

    Science.gov (United States)

    2011-06-09

    ..., China and/or Taiwan.\\5\\ This blanket authorization was later amended to permit exports to Canada, Mexico... imported into the United States from foreign sources on a short-term or spot market basis. The LNG would be... liability company and wholly owned subsidiary of Zachary American Infrastructure, LLC, which owns a 55...

  14. Better for Patients, or Better for Business-Do We Really Have To Choose?

    Science.gov (United States)

    Hafner, Zachary

    2017-12-01

    A trend that is likely to continue in 2018 is the rise of consumerism and expansion of the consumer-driven marketplace. But investing in this is pricey and in an era of shrinking margins is "better for patients" always "better for business?" The Advisory Board's Zachary Hafner answers with a resounding "yes!"

  15. The Army’s Ground Combat Vehicle (GCV) Program: Background and Issues for Congress

    Science.gov (United States)

    2014-02-28

    Daily, May 13, 2009. 6 Ibid. 7 John T. Bennett, “Carter: FCS Successor Effort Could Have Many Primes,” Defense News, May 18, 2009. 8 Marjorie...2014. 40 Zachary Fryer- Biggs , “U.S. Army Official Defends GCV Against Attacks,” Defense News, February 25, 2014. 41Assistant Secretary of the Army

  16. The Eastern side of the Westernmost Europeans: Insights from subclades within Y-chromosome haplogroup J-M304.

    Science.gov (United States)

    Manco, Licínio; Albuquerque, Joana; Sousa, Maria Francisca; Martiniano, Rui; de Oliveira, Ricardo Costa; Marques, Sofia; Gomes, Verónica; Amorim, António; Alvarez, Luís; Prata, Maria João

    2018-03-01

    We examined internal lineages and haplotype diversity in Portuguese samples belonging to J-M304 to improve the spatial and temporal understanding of the introduction of this haplogroup in Iberia, using the available knowledge about the phylogeography of its main branches, J1-M267 and J2-M172. A total of 110 males of Portuguese descent were analyzed for 17 Y-chromosome bi-allelic markers and seven Y-chromosome short tandem repeats (Y-STR) loci. Among J1-M267 individuals (n = 36), five different sub-haplogroups were identified, with the most common being J1a2b2-L147.1 (∼72%), which encompassed the majority of representatives of the J1a2b-P58 subclade. One sample belonged to the rare J1a1-M365.1 lineage and presented a core Y-STR haplotype consistent with the Iberian settlement during the fifth century by the Alans, a people of Iranian heritage. The analysis of J2-M172 Portuguese males (n = 74) enabled the detection of the two main subclades at very dissimilar frequencies, J2a-M410 (∼80%) and J2b-M12 (∼20%), among which the most common branches were J2a1(xJ2a1b,h)-L26 (22.9%), J2a1b(xJ2a1b1)-M67 (20.3%), J2a1h-L24 (27%), and J2b2-M241 (20.3%). While previous inferences based on modern haplogroup J Y-chromosomes implicated a main Neolithic dissemination, here we propose a later arrival of J lineages into Iberia using a combination of novel Portuguese Y-chromosomal data and recent evidence from ancient DNA. Our analysis suggests that a substantial tranche of J1-M267 lineages was likely carried into the Iberian Peninsula as a consequence of the trans-Mediterranean contacts during the first millennium BC, while most of the J2-M172 lineages may be associated with post-Neolithic population movements within Europe. © 2017 Wiley Periodicals, Inc.

  17. 107 Knowledge Management: The Case for Kenya Zachary Mosoti ...

    African Journals Online (AJOL)

    zmosoti

    already existed within the institution's boundaries so the intellectual capital of the .... facilitate the sharing and utilization of knowledge across all sectors. .... suppliers and from public research institutions including universities and government.

  18. Raytheon, Estonia agree to cyber pact / Zachary Fryer-Biggs

    Index Scriptorium Estoniae

    Fryer-Biggs, Zachary

    2015-01-01

    USA ettevõte on valmis tegema Eestiga koostööd kübervõimekuse arendamisel. Kaitseministeeriumi asekantsleri Mikk Marrani sõnul on Eesti ja USA kaitsetööstuselane koostöö Eesti strateegilistes huvides

  19. Research

    African Journals Online (AJOL)

    abp

    16 oct. 2015 ... Page number not for citation purposes. 1. Prévalence de l'hypertension artérielle dans ..... PAD de 9 mm Hg après une cigarette dans un groupe d'hypertendu. Ceci montre l'influence du tabac sur la pression .... Burhole E Masumbuko,Daniel Lemogoum, Zacharie M. Kashongwe, Jean-Paul Degaute, Jeff M ...

  20. Central and Peripheral Mechanisms of Antipsychotic Medication-Induced Metabolic Dysregulation

    Science.gov (United States)

    2016-10-01

    may also significantly contribute to our fundamental understanding of obesity and lead to novel treatments. Since APD-induced metabolic disturbances...York, NY 10032 Department of Psychology , Yeshiva University, New York, NY 10016 Sponsor: Jonathan A. Javitch Background: Antipsychotic drugs...Zachary Freyberg Departments of Psychiatry, Pharmacology & Medicine, Columbia University, New York, NY 10032 Department of Psychology , Yeshiva

  1. Central and Peripheral Mechanisms of Antipsychotic Medication Induced Metabolic Dysregulation

    Science.gov (United States)

    2016-10-01

    effects characterized by substantial weight gain, glucose intolerance, insulin resistance , hypertension and dyslipidemia as well as increased risks for...sufficiently powered to resolve potential effects of D2R absence on APDs’ effects on glucose tolerance, insulin resistance , glucose stimulated insulin ...Zachary Freyberg, to optimize the dietary conditions responsible for inducing the development of insulin resistance . Initial studies with standard 60

  2. Vana materjali taaskasutamine - lisaväärtus renoveeritavale ehitusele / Tarmo-Andre Elvisto

    Index Scriptorium Estoniae

    Elvisto, Tarmo Andre, 1964-

    2004-01-01

    Vanade hoonete väärtustamisest, vanade materjalide (konstruktiivsed materjalid: palgid, talad, katusekivid jm., detailid: uksed, aknad, sepised jm., ehisdetailid: karniisid, puitpits jm., interjöörielemendid: kahhelahjud, trepid, lae- ja põrandalauad jm.) taaskasutamine eelkõige vanade majade renoveerimisel ja restaureerimisel

  3. Inference for Continuous-Time Probabilistic Programming

    Science.gov (United States)

    2017-12-01

    network of Ising model dynamics. The Ising model is a well-known interaction model with applications in many fields includ- ing statistical mechanics...well- known interaction model with applications in many fields including statistical mechanics, genetics, and neuroscience. This is a Markovian model...chains. The Annals of Mathematical Statistics , 37(6):1554–1563, 1966. ISSN 00034851. URL http://www.jstor.org/stable/2238772. Zachary C Lipton, David C

  4. Mission Command: The Historical Roots of Mission Command in the US Army

    Science.gov (United States)

    2015-05-21

    Bauer, Zachary Taylor: Soldier, Planter, Statesman, of the Old Southwest (Baton Rouge, LA : Louisiana State University Press, 1985), 1. General...Battle of Buena Vista , he observed the battle from so close that his coat ended up riddled with holes from grape shot.25 General Taylor created a...1846 report to Colonel Joseph Totten he describes his observations of the battle of Palo Alto and Resaca De La Palma. Scarritt served temporarily

  5. Defense Acquisition Reform: Background, Analysis, and Issues for Congress

    Science.gov (United States)

    2014-05-23

    provided to CRS by Semiconductor Industry, October, 2013. 33 Zachary Fryer- Biggs , “Looking Beyond Defense: Firms Grow Revenue—By Diversifying,” DefenseNews...was chartered based on the authority set forth in Section 854 of the John Warner National Defense Authorization Act for 2007 (P.L. 109-364). See...Secretary of Defense for Acquisition, Technology, and Logistics John Young echoed this sentiment, stating “the enterprise will often pressure acquisition

  6. Cathodoluminescence and Thermoluminescence of Undoped LTB and LTB:A (A = Cu, Ag, Mn)

    Science.gov (United States)

    2013-03-01

    and Mn Ions for Nonlinear Applications.” Acta Physica Polonica A 107, no. 3 (2005): 507-518. [22] Kimball Physics, Inc.. Operator’s Manual: EMG...CATHODOLUMINESCENCE AND THERMOLUMINESCENCE OF UNDOPED LTB AND LTB:A ( A = Cu, Ag, Mn) THESIS Zachary L. Hadfield, USA AFIT-ENP-13-M-13...STATEMENT A . APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED The views expressed in this thesis are those of the author and

  7. The prognostic value of Her4 receptor isoform expression in triple-negative and Her2 positive breast cancer patients

    International Nuclear Information System (INIS)

    Machleidt, Anna; Buchholz, Stefan; Diermeier-Daucher, Simone; Zeman, Florian; Ortmann, Olaf; Brockhoff, Gero

    2013-01-01

    Not only four but rather seven different human epidermal growth factor receptor related (Her) receptor tyrosine kinases (RTKs) have been described to be expressed in a variety of normal and neoplastic tissues: Her1, Her2, Her3, and additionally four Her4 isoforms have been identified. A differential expression of Her4 isoforms does not, however, play any role in either the molecular diagnostics or treatment decision for breast cancer patients. The prognostic and predictive impact of Her4 expression in breast cancer is basically unclear. We quantified the Her4 variants JM-a/CYT1, JM-a/CYT2, JM-b/CYT1, and JM-b/CYT2 by isoform-specific polymerase chain reaction (qPCR) in (i) triple-negative, (ii) Her2 positive breast cancer tissues and (iii) in benign breast tissues. In all three tissue collectives we never found the JM-b/CYT1 or the JM-b/CYT2 isoform expressed. In contrast, the two JM-a/CYT1 and JM-a/CYT2 isoforms were always simultaneously expressed but at different ratios. We identified a positive prognostic impact on overall survival (OS) in triple-negative and event-free survival (EFS) in Her2 positive patients. This finding is independent of the absolute JM-a/CYT1 to JM-a/CYT2 expression ratio. In Her2 positive patients, Her4 expression only has a favorable effect in estrogen-receptor (ER)-positive but not in ER-negative individuals. In summary, JM-a/CYT1 and JM-a/CYT2 but not JM-b isoforms of the Her4 receptor are simultaneously expressed in both triple-negative and Her2 positive breast cancer tissues. Although different expression ratios of the two JM-a isoforms did not reveal any additional information, Her4 expression basically indicates a prolonged EFS and OFS. An extended expression analysis that takes all Her receptor homologs, including the Her4 isoforms, into account might render more precisely the molecular diagnostics required for the development of optimized targeted therapies

  8. J.M. v.d. Westhuysen

    African Journals Online (AJOL)

    "While pure science goes very deeply into a very limited problern - so that the definition ... ficiencies of national livestock and the low market pene- tration of AI in South ..... in vitro penetration tests under various experimental conditions. Fertility ...

  9. Anesthesia for the patient undergoing total knee replacement: current status and future prospects

    OpenAIRE

    Turnbull,Zachary; Sastow,Dahniel; Giambrone,Gregory; Tedore,Tiffany

    2017-01-01

    Zachary A Turnbull, Dahniel Sastow, Gregory P Giambrone, Tiffany Tedore Department of Anesthesiology, Weill Cornell Medical College, New York, NY, USA Abstract: Total knee arthroplasty (TKA) has become one of the most common orthopedic surgical procedures performed nationally. As the population and surgical techniques for TKAs have evolved over time, so have the anesthesia and analgesia used for these procedures. General anesthesia has been the dominant form of anes...

  10. Experimental Characterization of Wings for a Hawkmoth-Sized Micro Air Vehicle

    Science.gov (United States)

    2014-03-27

    butterfly where the modeshapes were found to be identical with the Hawkmoth, lending more credence to the assertion that the wing modal ratios...EXPERIMENTAL CHARACTERIZATION OF WINGS FOR A HAWKMOTH-SIZED MICRO AIR VEHICLE THESIS Zachary R. Brown, Lieutenant Commander, USN AFIT-ENY-14-M-10...of the U.S. Government and is not subject to copyright protection in the United States. AFIT-ENY-14-M-10 EXPERIMENTAL CHARACTERIZATION OF WINGS FOR A

  11. Computational modeling as a tool for water resources management: an alternative approach to problems of multiple uses

    Directory of Open Access Journals (Sweden)

    Haydda Manolla Chaves da Hora

    2012-04-01

    Full Text Available Today in Brazil there are many cases of incompatibility regarding use of water and its availability. Due to the increase in required variety and volume, the concept of multiple uses was created, as stated by Pinheiro et al. (2007. The use of the same resource to satisfy different needs with several restrictions (qualitative and quantitative creates conflicts. Aiming to minimize these conflicts, this work was applied to the particular cases of Hydrographic Regions VI and VIII of Rio de Janeiro State, using computational modeling techniques (based on MOHID software – Water Modeling System as a tool for water resources management.

  12. Cell Morphology Change by the Ultraviolet Ray Irradiation

    International Nuclear Information System (INIS)

    Park, Myung Joo; Matuo, Yoichirou; Akiyama, Yoko; Izumi, Yoshinobu; Nishijima, Shigehiro

    2009-01-01

    The effect of low doses of ultraviolet (UV) irradiation on morphology changes of cell has been studied based on the observation of the cell length. It was shown that UV-irradiated cell has different behavior in comparison with nonirradiated cell. From the histogram of cell-length distribution, it was confirmed that cell cycle of non irradiated cell was 28 hours, and that cell cycle of irradiated cell with dose of 20 Jm -2 was delayed (39 hours), while irradiated cell with 40 Jm -2 and 60 Jm -2 did not divide and kept growing continuously. It was supposed that in case of 20 Jm -2 of irradiation dose, the cell cycle was delayed because the checkpoint worked in order to repair DNA damage induced by generation of pyrimidine dimer, reactive oxygen species and so on. It was also supposed that in case of 40 Jm -2 and 60 Jm -2 of irradiation dose, overgrowth was induced because the checkpoint was not worked well. The morphology of overgrown cell was similar to that of normally senescent cell. Therefore, it was considered that cell senescence was accelerated by UV irradiation with irradiation doses of 40 Jm -2 and 60 Jm -2

  13. Journal of Mormon History Vol. 35, No. 3, 2009

    OpenAIRE

    2009-01-01

    LETTERS --Passing of Two Exemplars Joseph Johnstun, vi --In Praise of Will Bagley Sherman L. Fleek, vii ARTICLES --Conversion amid Conflict: Mormon Proselytizing in Russian Finland, 1861–1914 Zachary R. Jones, 1 --The Forms and the Power: The Development of Mormon Ritual Healing to 1847 Jonathan A. Stapley and Kristine Wright, 42 --Preserving the Record and Memory of the Female Relief Society of Nauvoo, 1842–92 Jill Mulvay Derr and Carol Cornwall Madsen, 88 --The Reed Smo...

  14. Second Seminole War: Establishing Favorable Conditions for Conflict Resolution

    Science.gov (United States)

    2013-05-23

    Papers, 59; Mahon, 95; Woodburne Potter , The War in Florida: Being an Exposition of Its Causes, and an Accurate History of the Campaigns of Generals... Harry A. Kersey, Jr., and Michael Petersen, “‘Was I a Member of Congress…’: Zachary Taylor’s Letter to John J. Crittenden, January 12, 1838...English and French people within the Canadian provinces rather one of discord between the people and their government, Durham issued his report to the

  15. Evaluation of the Impact of Kerojet (trademark) Aquarius Water Scavenger Additive on the Thermal Stability of Jet A Fuels

    Science.gov (United States)

    2014-12-01

    Morris Jr. Fuels and Energy Branch Turbine Engine Division James R. Shardo, Ashil Kim Higgins , Rhonda Cook, Zachary West, and Sam Tanner...5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 62203F 6. AUTHOR(S) Robert W. Morris Jr. (AFRL/RQTF) James R. Shardo, Ashil Kim Higgins , Rhonda...played a critical role in the completion of this work: • Chris Klenke, AFRL/RQTM for SEM analyses. • Dr. Paula Zard, Palox Ltd. - for sponsoring this

  16. Advanced maternal age: ethical and medical considerations for assisted reproductive technology

    OpenAIRE

    Harrison,Brittany; Hilton,Tara; Rivière,Raphaël; Ferraro,Zachary; Deonandan,Raywat; Walker,Mark

    2017-01-01

    Brittany J Harrison,1 Tara N Hilton,1 Raphaël N Rivière,1 Zachary M Ferraro,1–3 Raywat Deonandan,4 Mark C Walker1–3,51Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada; 2Division of Maternal-Fetal Medicine, University of Ottawa, The Ottawa Hospital, Ottawa, ON, Canada; 3Ottawa Hospital Research Institute, The Ottawa Hospital, Ottawa, ON, Canada; 4University of Ottawa Interdisciplinary School of Health Sciences, Ottawa, ON, Canada; 5...

  17. DHS Internship Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Tew, Karen [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-09-01

    I spent the last ten weeks working in the Systems Biology department at Sandia National Laboratories in Livermore, CA. Under the direction of Zachary Bent, I helped do preliminary testing/optimization of a vacuum-driven, capture-based system for pathogen RNA transcript enrichment. I also worked on a project to create mutant Yersinia enterocolitica strains in order to test which genes are involved in intracellular pathogen virulence, as well as sequencing several Klebsiella pneumoniae samples for use by a bioinformaticist.

  18. Difunctional bacteriophage conjugated with photosensitizers for Candida albicans-targeting photodynamic inactivation.

    Science.gov (United States)

    Dong, Shuai; Shi, Hongxi; Zhang, Xintong; Chen, Xi; Cao, Donghui; Mao, Chuanbin; Gao, Xiang; Wang, Li

    2018-01-01

    Candida albicans is the most prevalent fungal pathogen of the human microbiota, causing infections ranging from superficial infections of the skin to life-threatening systemic infections. Due to the increasing occurrence of antibiotic-resistant C. albicans strains, new approaches to control this pathogen are needed. Photodynamic inactivation is an emerging alternative to treat infections based on the interactions between visible light and photosensitisers, in which pheophorbide a (PPA) is a chlorophyll-based photosensitizer that could induce cell death after light irradiation. Due to PPA's phototoxicity and low efficiency, the main challenge is to implement photosensitizer cell targeting and attacking. In this study, PPA was conjugated with JM-phage by EDC/NHS crosslinking. UV-Vis spectra was used to determine the optimum conjugation percentages of PPA and JM-phage complex for photodynamic inactivation. After photodynamic inactivation, the efficacy of PPA-JM-phage was assessed by performing in vitro experiments, such as MTS assay, scanning electron microscopy, measurement of dysfunctional mitochondria, ROS accumulation, S cell arrest and apoptotic pathway. A single-chain variable-fragment phage (JM) with high affinity to MP65 was screened from human single-fold single-chain variable-fragment libraries and designed as a binding target for C. albicans cells. Subsequently, PPa was integrated into JM phage to generate a combined nanoscale material, which was called PPA-JM-phage. After photodynamic inactivation, the growth of C. albicans was inhibited by PPA-JM-phage and apoptosis was observed. Scanning electron microscopy analysis revealed shrinking and rupturing of C. albicans . We also found that depolarization of mitochondrial membrane potential was decreased and intracellular reactive oxygen species levels were elevated significantly in C. albicans inhibited by PPA-JM-phage. Additionally, PPA-JM-phage also lead to S-phase arrest, and metacaspase activation

  19. Limited near and far transfer effects of Jungle Memory working memory training on learning mathematics in children with attentional and mathematical difficulties

    Directory of Open Access Journals (Sweden)

    Michel Nelwan

    2016-09-01

    Full Text Available The goal of this randomized controlled trial was to investigate whether Jungle Memory working memory training (JM affects performance on working memory tasks, performance in mathematics and gains made on a mathematics training (MT in school aged children between 9-12 years old (N = 64 with both difficulties in mathematics, as well as in attention and working memory. Children were randomly assigned to three groups and were trained in two periods: (1 JM first, followed by MT, (2 MT first, followed by JM, and (3 a control group that received MT only. Bayesian analyses showed possible short term effects of JM on near transfer measures of verbal working memory, but none on visual working memory. Furthermore, support was found for the hypothesis that children that received JM first, performed better after MT than children who did not follow JM first or did not train with JM at all. However, these effects could be explained at least partly by frequency of training effects, possibly due to motivational issues, and training-specific factors. Furthermore, it remains unclear whether the effects found on math improvement were actually mediated by gains in working memory. It is argued that JM might not train the components of working memory involved in mathematics sufficiently. Another possible explanation can be found in the training’s lack of adaptivity, therefore failing to provide the children with tailored instruction and feedback. Finally, it was hypothesized that, since effect sizes are generally small, training effects are bound to a critical period in development.

  20. Effect of UV-B (302 nm) irradiation on isolated rat hepatocytes

    International Nuclear Information System (INIS)

    Lahiri, S.; Habibullah, C.M.; Ayesha, Q.; Khan, A.A.; Srinivas, V.K.; Naithani, R.

    1995-01-01

    The present study aimed to evaluate the effect of UV-B irradiation on the functional integrity, and the metabolic and detoxifying capacity of isolated rat hepatocytes. Isolated rat hepatocytes were irradiated in various doses (400 Jm -2 , 600 Jm -2 , 800 Jm -2 and 1000 Jm -2 ). The cells were assayed for total lactate dehydrogenase, Na + -K + -ATPase, ATPase, ornithine carbamyltransferase activity (OCT) and urea production capacity. Lactate dehydrogenase and Na + -K + -ATPase activity were significantly decreased in all four irradiated groups (P<0.001), whereas viability, OCT and urea production capacity showed no alterations. (au) 22 refs

  1. Bilateral lower extremity hyperkeratotic plaques: a case report of ichthyosis vulgaris

    Directory of Open Access Journals (Sweden)

    Leight H

    2015-09-01

    Full Text Available Hayley Leight, Zachary Zinn, Omid JalaliDepartment of Dermatology, West Virginia University, Morgantown, WV, USA Abstract: Here, we report a case of a middle-aged woman presenting with severe, long-standing, hyperkeratotic plaques of the lower extremities unrelieved by over-the-counter medications. Initial history and clinical findings were suggestive of an inherited ichthyosis. Ichthyoses are genetic disorders characterized by dry scaly skin and altered skin-barrier function. A diagnosis of ichthyosis vulgaris was confirmed by histopathology. Etiology, prevalence, and treatment options are discussed. Keywords: filaggrin gene, FLG, profilaggrin, keratohyalin granules, hyperkeratosis

  2. Deterring Malicious Behavior in Cyberspace

    Science.gov (United States)

    2015-01-01

    www.armed-services.senate .gov/imo/media/doc/14-16%20-%203-11-14.pdf. 31. Zachary Fryer- Biggs , “US Cyber Moves beyond Protection,” Defense News, 16...ed., ed. Schuyler Foerster and Edward Wright (Baltimore, MD: Johns Hopkins University Press, 1990), 47–51. 34. Roger G. Harrison, Deron R. Jackson...ccsfiles.blob.core.windows.net/web-site/file/81d5ad9c89d242a7a555658e604 fdc43/Critical%20Controls%20v4.1.pdf. 56. John Pescatore and Tony Sager, Critical Security

  3. A Prospective Comparison of Transcutaneous and Serum Bilirubin Within Brief Time Intervals.

    Science.gov (United States)

    Jones, Denise F; McRea, Abigail R; Knowles, James D; Lin, Feng-Chang; Burnette, Erin; Reller, Lara A; Lohr, Jacob A

    2017-10-01

    The American Academy of Pediatrics recommends screening newborns ≥35 weeks' gestation with total serum bilirubin (TSB) or transcutaneous bilirubin (TcB) to detect hyperbilirubinemia. Retrospective studies show TcB measurements strongly correlate with TSB; however, few prospective trials document this relationship. Furthermore, Dräger's newest TcB instrument, JM-105, remains unstudied in the United States. We measure TcB on foreheads and sternums of newborns using JM-105 and Bilichek devices within 30 minutes of TSB measurement. We find best overall TcB/TSB correlation with JM-105 on the sternum (mean TcB-TSB difference: -0.21 ± 1.15 mg/dL). Correlations between paired measurements for TcB on the sternum using JM-105 were 0.93 for all TSB levels (n = 178), 0.82 for TSB > 10 (n = 19), 0.69 for TSB > 12 (n = 11), and 0.52 for TSB > 15 (n = 6). TcB accuracy via JM-105 on the sternum significantly differed among races ( P < .001). For 5% of paired measurements, TcB with JM-105 on the sternum underestimated TSB by ≥2 mg/dL, and for <1% by ≥3 mg/dL.

  4. Physical interaction of junctophilin and the CaV1.1 C terminus is crucial for skeletal muscle contraction.

    Science.gov (United States)

    Nakada, Tsutomu; Kashihara, Toshihide; Komatsu, Masatoshi; Kojima, Katsuhiko; Takeshita, Toshikazu; Yamada, Mitsuhiko

    2018-04-24

    Close physical association of Ca V 1.1 L-type calcium channels (LTCCs) at the sarcolemmal junctional membrane (JM) with ryanodine receptors (RyRs) of the sarcoplasmic reticulum (SR) is crucial for excitation-contraction coupling (ECC) in skeletal muscle. However, the molecular mechanism underlying the JM targeting of LTCCs is unexplored. Junctophilin 1 (JP1) and JP2 stabilize the JM by bridging the sarcolemmal and SR membranes. Here, we examined the roles of JPs in localization and function of LTCCs. Knockdown of JP1 or JP2 in cultured myotubes inhibited LTCC clustering at the JM and suppressed evoked Ca 2+ transients without disrupting JM structure. Coimmunoprecipitation and GST pull-down assays demonstrated that JPs physically interacted with 12-aa residues in the proximal C terminus of the Ca V 1.1. A JP1 mutant lacking the C terminus including the transmembrane domain (JP1ΔCT) interacted with the sarcolemmal/T-tubule membrane but not the SR membrane. Expression of this mutant in adult mouse muscles in vivo exerted a dominant-negative effect on endogenous JPs, impairing LTCC-RyR coupling at triads without disrupting JM morphology, and substantially reducing Ca 2+ transients without affecting SR Ca 2+ content. Moreover, the contractile force of the JP1ΔCT-expressed muscle was dramatically reduced compared with the control. Taken together, JPs recruit LTCCs to the JM through physical interaction and ensure robust ECC at triads in skeletal muscle.

  5. A second case of the thrid alexia in pure form

    DEFF Research Database (Denmark)

    Starrfelt, Randi; Gade, Anders; Gerlach, Christian

    2000-01-01

    We present a patient (J.M.) with severe alexia and agraphia in the absence of aphasia, and with intact reading and writing of numbers. J.M., a right- handed 18-year-old man, presented with alexia and agraphia after concus- sion. CT and MR were normal. J.M. is impaired in identifying, writing......, and copying letters. His reading and writing of numbers are normal, as is his written arithmetic. Object naming is within normal range, and his copy- ing and drawing of figures and objects are good. In a single letter identi- fication task, J.M. was able to identify only 13/29 uppercase letters and 18...... is good, as is his oral spelling of dictated words. In writing, letters are partly superimposed on each other, making the words virtually unreadable. There are no obvious spelling errors, but some letters are poorly formed. By contrast to his reading, J.M. was able to identify written numbers (1–7 digits...

  6. Recensiones

    Directory of Open Access Journals (Sweden)

    M.L. Neira

    1995-01-01

    Full Text Available RESEÑA 1 de : Blázquez, J.M.; Martínez Pinna, J.; Montero, S. Historia de ias Religiones antiguas. Oriente, Grecia y Roma. Madrid : Cátedra, 1993. RESEÑA 2 de : Blázquez, J.M. Fenicios, Griegos y Cartagineses en Occidente. Madrid : Cátedra. RESEÑA 3 de : Alvar, J.; Blázquez, J.M.; Fernández, S.; López, G.; Monteagudo, A.(y otros. Cristianismo primitivo y religiones mistéricas. Madrid : Cátedra, 1995. RESEÑA 4 de : Blázquez, J.M.; Martínez Pinna, J.; Montero, S.; (y otros. Historia de las Religiones de la Europa Antigua. Madrid : Cátedra, 1994

  7. Watershed modeling tools and data for prognostic and diagnostic

    Science.gov (United States)

    Chambel-Leitao, P.; Brito, D.; Neves, R.

    2009-04-01

    's widely used in the world. Watershed models can be characterized by the high number of processes associated simulated. The estimation of these processes is also data intensive, requiring data on topography, land use / land cover, agriculture practices, soil type, precipitation, temperature, relative humidity, wind and radiation. Every year new data is being made available namely by satellite, that has allow to improve the quality of model input and also the calibration of the models (Galvão et. al, 2004b). Tools to cope with the vast amount of data have been developed: data formatting, data retrieving, data bases, metadata bases. The high number of processes simulated in watershed models makes them very wide in terms of output. The SWAT model outputs were modified to produce MOHID compliant result files (time series and HDF). These changes maintained the integrity of the original model, thus guarantying that results remain equal to the original version of SWAT. This allowed to output results in MOHID format, thus making it possible to immediately process it with MOHID visualization and data analysis tools (Chambel-Leitão et. al 2007; Trancoso et. al, 2009). Besides SWAT was modified to produce results files in HDF5 format, this allows the visualization of watershed properties (modeled by SWAT) in animated maps using MOHID GIS. The modified version of SWAT described here has been applied to various national and European projects. Results of the application of this modified version of SWAT to estimate hydrology and nutrients loads to estuaries and water bodies will be shown (Chambel-Leitão, 2008; Yarrow & Chambel-Leitão 2008; Chambel-Leitão et. al 2008; Yarrow & P. Chambel-Leitão, 2007; Yarrow & P. Chambel-Leitão, 2007; Coelho et. al., 2008). Keywords: Watershed models, SWAT, MOHID LAND, Hydrology, Nutrient Loads Arnold, J. G. and Fohrer, N. (2005). SWAT2000: current capabilities and research opportunities in applied watershed modeling. Hydrol. Process. 19, 563

  8. Lethal and mutagenic effects of XeCl laser radiation on Escherichia coli bacteria

    International Nuclear Information System (INIS)

    Tiflova, O.A.; Karu, T.J.; Furzikov, N.P.; Karbysheva, E.A.

    1987-01-01

    The survival rate and reversion to tryptophan-independence of Escherichia coli after XeCl laser irradiation (λ=308 nm) within the dose range deom 10 3 to 10 5 J/m 2 have been studied to show that LD 37 is 10 4 J/m 2 , the survival rate at a maximum dose of 10 5 J/m 2 is 1 per cent, and the number of mutants per 10 6 cells survived is 100

  9. Increased Protein Kinase A Activity in the Prkar1a-defective Mouse is Associated with Hyperarousal and Increased Anxiety

    Science.gov (United States)

    2011-03-09

    Armario A, and Castellanos JM. A comparison of corticoadrenal and gonadal responses to acute immobilization stress in rats and mice. Physiol Behav 32: 517...519, 1984. 9. Armario A, and Castellanos JM. Effect of acute and chronic stress on testosterone secretion in male rats. J Endocrinol Invest 7: 659...661, 1984. 10. Armario A, Castellanos JM, and Balasch J. Effects of chronic noise or daily water restriction on the pituitary-adrenal axis in male

  10. Dicty_cDB: SSM365 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available WGS-SbicolorF (JM107 adapted methyl filtered) Sorghum bicolor genomic clone hv90e08 5', DNA sequence. 36 1.2... 2 BZ330175 |BZ330175.1 hv90e08.g1 WGS-SbicolorF (JM107 adapted methyl filtered) ...rF (JM107 adapted methyl filtered) Sorghum bicolor genomic clone hz26f02 5', DNA sequence. 36 1.4 2 BZ628823... |BZ628823.1 ih62d12.g1 WGS-SbicolorF (DH5a methyl filtered) Sorghum bicolor geno...mic clone ih62d12 5', DNA sequence. 36 1.7 2 BZ340606 |BZ340606.1 ic39h07.b1 WGS-SbicolorF (JM107 adapted methyl filter

  11. Toxic clinical hypoxic radiation sensitizers plus radiation-induced toxicity

    International Nuclear Information System (INIS)

    Richmond, R.C.

    1984-01-01

    The operational definition espoused twelve years ago that clinical hypoxic radiation sensitizers should be nontoxic interferes with the recognition and research of useful radiation sensitizers. Eight years ago the toxic antitumor drug cis-dichlorodiammineplatinum(II) was reported to be a hypoxic radiation sensitizer and the selective antitumor action of this drug was stressed as potentially creating tumor-targeted radiation sensitization. This rationale of oxidative antitumor drugs as toxic and targeted clinical sensitizers is useful, and has led to the study reported here. The antitumor drug cis-(1,1-cyclobutane-dicarboxylato)diammineplatinum(II), or JM-8, is being tested in clinical trials. Cells of S. typhimurium in PBS in the presence of 0.2mM JM-8 are found to be sensitized to irradiation under hypoxic, but not oxic, conditions. JM-8 is nontoxic to bacteria at this concentration, but upon irradiation the JM-8 solution becomes highly toxic. This radiation induced toxicity of JM-8 preferentially develops from hypoxic solution, and thus contributes to the rationale of hypoxic tumor cell destruction

  12. Evaluation of Encapsulant Adhesion to Surface Metallization of Photovoltaic Cells: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Tracy, Jared; Dauskardt, Reinhold; Bosco, Nick

    2017-06-14

    Delamination of encapsulant materials from PV cell surfaces often appears to originate at regions with metallization. Using a fracture mechanics based metrology, the adhesion of EVA encapsulant to screen printed silver metallization was evaluated. At room temperature, the fracture energy, Gc [J/m2], of the EVA/silver interface (952 J/m2) was ~70% lower than that of the EVA/AR coating (>2900 J/m2) and ~60% lower than that of the EVA to the surface of cell (2265 J/m2). After only 300 hours of damp heat aging, the adhesion energy of the silver interface dropped to and plateaued at ~50-60 J/m2, while that of the EVA/AR coating and EVA/cell remained mostly unchanged. Elemental surface analysis showed that the EVA separates from the silver in a purely adhesive manner, indicating that bonds at the interface were likely displaced in the presence of humidity and elevated temperature, and may explain the propensity for delamination to occur at metallized surfaces in the field.

  13. Encapsulant Adhesion to Surface Metallization on Photovoltaic Cells

    Energy Technology Data Exchange (ETDEWEB)

    Tracy, Jared; Bosco, Nick; Dauskardt, Reinhold

    2017-11-01

    Delamination of encapsulant materials from PV cell surfaces often appears to originate at regions with metallization. Using a fracture mechanics based metrology, the adhesion of ethylene vinyl acetate (EVA) encapsulant to screen-printed silver metallization was evaluated. At room temperature, the fracture energy Gc [J/m2] of the EVA/silver interface (952 J/m2) was ~70% lower than that of the EVA/antireflective (AR) coating (>2900 J/m2) and ~60% lower than that of the EVA to the surface of cell (2265 J/m2). After only 300 h of damp heat aging, the adhesion energy of the silver interface dropped to and plateaued at ~50-60 J/m2 while that of the EVA/AR coating and EVA/cell remained mostly unchanged. Elemental surface analysis showed that the EVA separates from the silver in a purely adhesive manner, indicating that bonds at the interface were likely displaced in the presence of humidity and chemical byproducts at elevated temperature, which in part accounts for the propensity of metalized surfaces to delaminate in the field.

  14. Application of average adult Japanese voxel phantoms to evaluation of photon specific absorbed fractions

    International Nuclear Information System (INIS)

    Sato, Kaoru; Manabe, Kentaro; Endo, Akira

    2012-01-01

    Average adult Japanese male (JM-103) and female (JF-103) voxel (volume pixel) phantoms newly constructed at the Japan Atomic Energy Agency (JAEA) have average characteristics of body sizes and organ masses in adult Japanese. In JM-103 and JF-103, several organs and tissues were newly modeled for dose assessments based on tissue weighting factors of the 2007 Recommendations of the International Commission on Radiological Protection(ICRP). In this study, SAFs for thyroid, stomach, lungs and lymphatic nodes of JM-103 and JF-103 phantoms were calculated, and were compared with those of other adult Japanese phantoms based on individual medical images. In most cases, differences in SAFs between JM-103, JF-103 and other phantoms were about several tens percent, and was mainly attributed to mass differences of organs, tissues and contents. Therefore, it was concluded that SAFs of JM-103 and JF-103 represent those of average adult Japanese and that the two phantoms are applied to dose assessment for average adult Japanese on the basis of the 2007 Recommendations. (author)

  15. Substantiva mezi slovesem a jménem\

    Czech Academy of Sciences Publication Activity Database

    Kocková, Jana

    2017-01-01

    Roč. 99, č. 1 (2017), s. 55-64 ISSN 2336-6591 Institutional support: RVO:68378017 Keywords : verbal nouns * event nominals * Czech * Russian Subject RIV: AI - Linguistics OBOR OECD: Specific languages

  16. Practical quantum private query with better performance in resisting joint-measurement attack

    Science.gov (United States)

    Wei, Chun-Yan; Wang, Tian-Yin; Gao, Fei

    2016-04-01

    As a kind of practical protocol, quantum-key-distribution (QKD)-based quantum private queries (QPQs) have drawn lots of attention. However, joint-measurement (JM) attack poses a noticeable threat to the database security in such protocols. That is, by JM attack a malicious user can illegally elicit many more items from the database than the average amount an honest one can obtain. Taking Jacobi et al.'s protocol as an example, by JM attack a malicious user can obtain as many as 500 bits, instead of the expected 2.44 bits, from a 104-bit database in one query. It is a noticeable security flaw in theory, and would also arise in application with the development of quantum memories. To solve this problem, we propose a QPQ protocol based on a two-way QKD scheme, which behaves much better in resisting JM attack. Concretely, the user Alice cannot get more database items by conducting JM attack on the qubits because she has to send them back to Bob (the database holder) before knowing which of them should be jointly measured. Furthermore, JM attack by both Alice and Bob would be detected with certain probability, which is quite different from previous protocols. Moreover, our protocol retains the good characters of QKD-based QPQs, e.g., it is loss tolerant and robust against quantum memory attack.

  17. Visual recognition of age class and preference for infantile features: implications for species-specific vs universal cognitive traits in primates.

    Directory of Open Access Journals (Sweden)

    Anna Sato

    Full Text Available Despite not knowing the exact age of individuals, humans can estimate their rough age using age-related physical features. Nonhuman primates show some age-related physical features; however, the cognitive traits underlying their recognition of age class have not been revealed. Here, we tested the ability of two species of Old World monkey, Japanese macaques (JM and Campbell's monkeys (CM, to spontaneously discriminate age classes using visual paired comparison (VPC tasks based on the two distinct categories of infant and adult images. First, VPCs were conducted in JM subjects using conspecific JM stimuli. When analyzing the side of the first look, JM subjects significantly looked more often at novel images. Based on analyses of total looking durations, JM subjects looked at a novel infant image longer than they looked at a familiar adult image, suggesting the ability to spontaneously discriminate between the two age classes and a preference for infant over adult images. Next, VPCs were tested in CM subjects using heterospecific JM stimuli. CM subjects showed no difference in the side of their first look, but looked at infant JM images longer than they looked at adult images; the fact that CMs were totally naïve to JMs suggested that the attractiveness of infant images transcends species differences. This is the first report of visual age class recognition and a preference for infant over adult images in nonhuman primates. Our results suggest not only species-specific processing for age class recognition but also the evolutionary origins of the instinctive human perception of baby cuteness schema, proposed by the ethologist Konrad Lorenz.

  18. Impact of Obesity on Tamoxifen Chemoprevention in a Model of Ductal Carcinoma in Situ

    Science.gov (United States)

    2012-10-01

    Sarah M. Smith. McDonald JM*, Dunlap SM*, Cogdell D, Dunmire V, Wei Q, Starzinski-Powitz A, Sawaya R, Bruner J, Fuller GN, Aldape K, and Zhang W...Sciences 104(28):11736-41, July 2007. Moore LM, Holmes KM, Smith SM, Wu Y, Tchougounova E, Uhrbom L, Sawaya R, Bruner JM, Fuller GN, and Zhang W... Bruner JM Kuang J, Yu H, Fuller GN and Zhang W. Inhibition of gliomagenesis and attenuation of mitotic transition by MIIP. Oncogene 29(24):3501-8, June

  19. Arguments for theory-based pharmacy practice research

    DEFF Research Database (Denmark)

    Nørgaard, Lotte Stig; Traulsen, Janine Marie; Bissell, Paul

    2000-01-01

    Nørgaard LS, Morgall JM, Bissell P. . International Journal of Pharmacy Practice 2000; 8 (2): 77-81.......Nørgaard LS, Morgall JM, Bissell P. . International Journal of Pharmacy Practice 2000; 8 (2): 77-81....

  20. Difunctional bacteriophage conjugated with photosensitizers for Candida albicans-targeting photodynamic inactivation

    Directory of Open Access Journals (Sweden)

    Dong S

    2018-04-01

    Full Text Available Shuai Dong,1,2 Hongxi Shi,1 Xintong Zhang,1,2 Xi Chen,1 Donghui Cao,2 Chuanbin Mao,3,4 Xiang Gao,1 Li Wang1 1Key Laboratory of Molecular Epigenetics of Ministry of Education, Institute of Genetics and Cytology, Northeast Normal University, 2First Hospital of Jilin University, Changchun, Jilin, 3School of Materials Science and Engineering, Zhejiang University, Hangzhou, Zhejiang, China; 4Department of Chemistry and Biochemistry, Stephenson Life Science Research Center, University of Oklahoma, Norman, OK, USA Background: Candida albicans is the most prevalent fungal pathogen of the human microbiota, causing infections ranging from superficial infections of the skin to life-threatening systemic infections. Due to the increasing occurrence of antibiotic-resistant C. albicans strains, new approaches to control this pathogen are needed. Photodynamic inactivation is an emerging alternative to treat infections based on the interactions between visible light and photosensitisers, in which pheophorbide a (PPA is a chlorophyll-based photosensitizer that could induce cell death after light irradiation. Due to PPA’s phototoxicity and low efficiency, the main challenge is to implement photosensitizer cell targeting and attacking. Methods: In this study, PPA was conjugated with JM-phage by EDC/NHS crosslinking. UV-Vis spectra was used to determine the optimum conjugation percentages of PPA and JM-phage complex for photodynamic inactivation. After photodynamic inactivation, the efficacy of PPA-JM-phage was assessed by performing in vitro experiments, such as MTS assay, scanning electron microscopy, measurement of dysfunctional mitochondria, ROS accumulation, S cell arrest and apoptotic pathway.Results: A single-chain variable-fragment phage (JM with high affinity to MP65 was screened from human single-fold single-chain variable-fragment libraries and designed as a binding target for C. albicans cells. Subsequently, PPa was integrated into JM phage to generate

  1. Dicty_cDB: SSL552 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 28 0.36 3 BZ330174 |BZ330174.1 hv90e08.b1 WGS-SbicolorF (JM107 adapted methyl filtered) Sorghum bicolor gen...S-SbicolorF (JM107 adapted methyl filtered) Sorghum bicolor genomic clone hv90e08 5', DNA sequence. 36 0.63 ...2 BZ335743 |BZ335743.1 hz26f02.g1 WGS-SbicolorF (JM107 adapted methyl filtered) Sorghum bicolor genomic clon...e hz26f02 5', DNA sequence. 36 0.68 2 BZ628823 |BZ628823.1 ih62d12.g1 WGS-SbicolorF (DH5a methyl filtered) S...06.1 ic39h07.b1 WGS-SbicolorF (JM107 adapted methyl filtered) Sorghum bicolor genomic clone ic39h07 5', DNA

  2. Discovery of imidazopyridine derivatives as highly potent respiratory syncytial virus fusion inhibitors.

    Science.gov (United States)

    Feng, Song; Hong, Di; Wang, Baoxia; Zheng, Xiufang; Miao, Kun; Wang, Lisha; Yun, Hongying; Gao, Lu; Zhao, Shuhai; Shen, Hong C

    2015-03-12

    A series of imidazolepyridine derivatives were designed and synthesized according to the established docking studies. The imidazopyridine derivatives were found to have good potency and physical-chemical properties. Several highly potent compounds such as 8ji, 8jl, and 8jm were identified with single nanomolar activities. The most potent compound 8jm showed an IC50 of 3 nM, lower microsome clearance and no CYP inhibition. The profile of 8jm appeared to be superior to BMS433771, and supported further optimization.

  3. Engineering the growth pattern and cell morphology for enhanced PHB production by Escherichia coli.

    Science.gov (United States)

    Wu, Hong; Chen, Jinchun; Chen, Guo-Qiang

    2016-12-01

    E. coli JM109∆envC∆nlpD deleted with genes envC and nlpD responsible for degrading peptidoglycan (PG) led to long filamentous cell shapes. When cell fission ring location genes minC and minD of Escherichia coli were deleted, E. coli JM109∆minCD changed the cell growth pattern from binary division to multiple fissions. Bacterial morphology can be further engineered by overexpressing sulA gene resulting in inhibition on FtsZ, thus generating very long cellular filaments. By overexpressing sulA in E. coli JM109∆envC∆nlpD and E. coli JM109∆minCD harboring poly(3-hydroxybutyrate) (PHB) synthesis operon phbCAB encoded in plasmid pBHR68, respectively, both engineered cells became long filaments and accumulated more PHB compared with the wild-type. Under same shake flask growth conditions, E. coli JM109∆minCD (pBHR68) overexpressing sulA grown in multiple fission pattern accumulated approximately 70 % PHB in 9 g/L cell dry mass (CDM), which was significantly higher than E. coli JM109∆envC∆nlpD and the wild type, that produced 7.6 g/L and 8 g/L CDM containing 64 % and 51 % PHB, respectively. Results demonstrated that a combination of the new division pattern with elongated shape of E. coli improved PHB production. This provided a new vision on the enhanced production of inclusion bodies.

  4. Quantum private query with perfect user privacy against a joint-measurement attack

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Yu-Guang, E-mail: yangyang7357@bjut.edu.cn [College of Computer Science and Technology, Beijing University of Technology, Beijing 100124 (China); State Key Laboratory of Information Security, Institute of Information Engineering, Chinese Academy of Sciences, Beijing 100093 (China); Liu, Zhi-Chao [College of Computer Science and Technology, Beijing University of Technology, Beijing 100124 (China); Li, Jian [School of Computer, Beijing University of Posts and Telecommunications, Beijing 100876 (China); Chen, Xiu-Bo [Information Security Center, State Key Laboratory of Networking and Switching Technology, Beijing University of Posts and Telecommunications, Beijing, 100876 (China); Zuo, Hui-Juan [College of Mathematics and Information Science, Hebei Normal University, Shijiazhuang 050024 (China); Zhou, Yi-Hua; Shi, Wei-Min [College of Computer Science and Technology, Beijing University of Technology, Beijing 100124 (China)

    2016-12-16

    The joint-measurement (JM) attack is the most powerful threat to the database security for existing quantum-key-distribution (QKD)-based quantum private query (QPQ) protocols. Wei et al. (2016) [28] proposed a novel QPQ protocol against the JM attack. However, their protocol relies on two-way quantum communication thereby affecting its real implementation and communication efficiency. Moreover, it cannot ensure perfect user privacy. In this paper, we present a new one-way QPQ protocol in which the special way of classical post-processing of oblivious key ensures the security against the JM attack. Furthermore, it realizes perfect user privacy and lower complexity of communication. - Highlights: • A special classical post-processing ensures the security against the JM attack. • It ensures perfect user privacy. • It ensures lower complexity of communication. Alice's conclusive key rate is 1/6.

  5. Quantum private query with perfect user privacy against a joint-measurement attack

    International Nuclear Information System (INIS)

    Yang, Yu-Guang; Liu, Zhi-Chao; Li, Jian; Chen, Xiu-Bo; Zuo, Hui-Juan; Zhou, Yi-Hua; Shi, Wei-Min

    2016-01-01

    The joint-measurement (JM) attack is the most powerful threat to the database security for existing quantum-key-distribution (QKD)-based quantum private query (QPQ) protocols. Wei et al. (2016) [28] proposed a novel QPQ protocol against the JM attack. However, their protocol relies on two-way quantum communication thereby affecting its real implementation and communication efficiency. Moreover, it cannot ensure perfect user privacy. In this paper, we present a new one-way QPQ protocol in which the special way of classical post-processing of oblivious key ensures the security against the JM attack. Furthermore, it realizes perfect user privacy and lower complexity of communication. - Highlights: • A special classical post-processing ensures the security against the JM attack. • It ensures perfect user privacy. • It ensures lower complexity of communication. Alice's conclusive key rate is 1/6.

  6. Baicklund transformation and multiple soliton solutions for the (3+1)-dimensional Jimbo-Miwa equation

    Institute of Scientific and Technical Information of China (English)

    张解放; 吴锋民

    2002-01-01

    We study an approach to constructing multiple soliton solutions of the (3+1)-dimensional nonlinear evolution equation. We take the (3+1)-dimensional Jimbo-Miwa (JM) equation as an example. Using the extended homogeneous balance method, one can find a Backlund transformation to decompose the (3+1)-dimensional JM equation into a linear partial differential equation and two bilinear partial differential equations. Starting from these linear and bilinear partial differential equations, some multiple soliton solutions for the (3+1)-dimensional JM equation are obtained by introducing a class of formal solutions.

  7. Radiation hygiene survey of radon in non-uranium mines in Hunan

    International Nuclear Information System (INIS)

    Zeng Xingyuan; Liu Hanqin; Xiao Renyi

    1989-01-01

    The 222 Rn daughter concentrations in 20 nonuranium mines in Hunan was described. The mean concentrations ranged from 0.21 ∼ 1107 μJm -3 , the highest levels being from 0.26 ∼ 5720 μJm -3 . In 65% of the mines, the mean concentration of radon daughters exceeded the permissible level for miners (8.3 μJm -3 ) set by Chinese hygiene standards. The cumulative exposure doses to miners ranged from 0.15 ∼ 765.7 WLM in these mines. The incidences of lung cancer among the miners in 9 mines were observed

  8. Thirdhand Smoke: What Are the Dangers to Nonsmokers?

    Science.gov (United States)

    ... Taylor Hays, M.D. Samet JM, et al. Secondhand smoke exposure: Effects in children. https://www.uptodate.com/home. Accessed June 9, 2017. Samet JM, et al. Control of secondhand smoke exposure. https://www.uptodate.com/home. Accessed June ...

  9. On the usability of `compensated temperature` output of Honeywell PPTR sensor for coastal oceanographic and limnological studies

    Digital Repository Service at National Institute of Oceanography (India)

    Mehra, P.; Joseph, A.; Desai, R.G.P.; Vijaykumar, K.; Sundar, D.; Tengali, S.

    and those of Aanderraa current meter's Fenwall GB 32JM19 thermistor probe and NIO water level recorder's YSI thermistor probes were encouraging. However, while the Fenwall GB 32JM19 thermistor probe and the YSI thermistor probes detects changes...

  10. Ungari päevad vabaõhumuuseumis / Tõnu Kalvet

    Index Scriptorium Estoniae

    Kalvet, Tõnu

    2002-01-01

    Kuie koolimajas avati Ibolya Bereczki ja Mária Káldy koostatud näitus "Laste maailm Ungaris". Väljas on fotod, mänguasjad jm., tutvustati ungari mänguasju. Sassi-Jaani talu õues õpetati looduslikest materjalidest lelude tegemist jm

  11. Disease: H00237 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Alter BP, Sheth S, Ramenghi U, Meerpohl J, Karlsson S, Liu JM, Leblanc T, Paley C, Kang EM, Leder EJ, Atsidaft..., Niewiadomska E, Matysiak M, Glader B, Atsidaftos E, Lipton JM, Beggs AH, Gleizes PE, Gazda HT ... TITLE ...

  12. Comparison of male chimeric mice generated from microinjection of JM8.N4 embryonic stem cells into C57BL/6J and C57BL/6NTac blastocysts.

    Science.gov (United States)

    Fielder, Thomas J; Yi, Charles S; Masumi, Juliet; Waymire, Katrina G; Chen, Hsiao-Wen; Wang, Shuling; Shi, Kai-Xuan; Wallace, Douglas C; MacGregor, Grant R

    2012-12-01

    To identify ways to improve the efficiency of generating chimeric mice via microinjection of blastocysts with ES cells, we compared production and performance of ES-cell derived chimeric mice using blastocysts from two closely related and commonly used sub-strains of C57BL/6. Chimeras were produced by injection of the same JM8.N4 (C57BL/6NTac) derived ES cell line into blastocysts of mixed sex from either C57BL/6J (B6J) or C57BL/6NTac (B6NTac) mice. Similar efficiency of production and sex-conversion of chimeric animals was observed with each strain of blastocyst. However, B6J chimeric males had fewer developmental abnormalities involving urogenital and reproductive tissues (1/12, 8%) compared with B6NTac chimeric males (7/9, 78%). The low sample size did not permit determination of statistical significance for many parameters. However, in each category analyzed the B6J-derived chimeric males performed as well, or better, than their B6NTac counterparts. Twelve of 14 (86%) B6J male chimeras were fertile compared with 6 of 11 (55%) B6NTac male chimeras. Ten of 12 (83%) B6J chimeric males sired more than 1 litter compared with only 3 of 6 (50%) B6NTac chimeras. B6J male chimeras produced more litters per productive mating (3.42 ± 1.73, n = 12) compared to B6NTac chimeras (2.17 ± 1.33, n = 6). Finally, a greater ratio of germline transmitting chimeric males was obtained using B6J blastocysts (9/14; 64%) compared with chimeras produced using B6NTac blastocysts (4/11; 36%). Use of B6J host blastocysts for microinjection of ES cells may offer improvements over blastocysts from B6NTac and possibly other sub-strains of C57BL/6 mice.

  13. Comment Hollywood figure l’intériorité dans les films « hollywoodiens » de David Lynch, Lost Highway (1997, Mulholland Dr. (2001 et Inland Empire (2006

    Directory of Open Access Journals (Sweden)

    David ROCHE

    2011-09-01

    Full Text Available L’article prend comme point de départ les travaux de Zachary Baqué et vise à montrer, à travers une étude diachronique, que les films hollywoodiens de Lynch ne le sont pas uniquement par leur représentation satirique d’un système corrompu qui compromet les ambitions qu’il suscite, ni même par la façon dont il retravaille les conventions génériques et narratives propres au cinéma hollywoodien. Hollywood est une présence à la fois horizontale et verticale, physique et abstraite, réelle et imaginaire, qui renvoie à la ville, au système, au cinéma et au rêve, si bien que la satire, la topographie, les motifs visuels parfois clichés et les références filmiques sont intimement liés en une expression de la subjectivité et de l’intérioritéThe article takes Zachary Baqué’s study of Los Angeles in the films of David Lynch as a starting point to explore David Lynch’s Hollywood movies. The author contends that the films offer more than a satirical representation of a corrupt, unhealthy system which threatens dreams and artistic creativity, or a parodic play on Hollywood genre and narrative conventions. Rather, Hollywood is a character, a presence, revealed as both horizontal and vertical, physical and abstract, evoking the city, the studio system, cinema and dreams, so that the satire, the visual motifs and clichés and the topography of Hollywood, and the references to Hollywood films, constitute a complex fabric of subjectivity and interiority.

  14. Optimization of the alcoholic fermentation of blueberry juice by AS ...

    African Journals Online (AJOL)

    AJL

    2012-02-21

    Feb 21, 2012 ... Kraft TFB, Schmidt BM, Yousef GG, Knight CTG, Cuendet M, Kang YH,. Pezzuto JM, Seigler D, ... Su MS, Silva JL (2006). Antioxidant activity ... 104: 182-187. Tian RR, Pan QH, Zhan JC, Li JM, Wan SB, Zhang QH, Huang WD.

  15. Heider balance in human networks

    Science.gov (United States)

    Gawroński, P.; Kułakowski, K.

    2005-07-01

    Recently, a continuous dynamics was proposed to simulate dynamics of interpersonal relations in a society represented by a fully connected graph. The final state of such a society was found to be identical with the so-called Heider balance (HB), where the society is divided into two mutually hostile groups. In the continuous model, a polarization of opinions was found in HB. Here we demonstrate that the polarization occurs also in Barabási-Albert networks, where the Heider balance is not necessarily present. In the second part of this work we demonstrate the results of our formalism, when applied to reference examples: the Southern women and the Zachary club.

  16. Showstopper! the breakneck race to create Windows NT and the next generation at Microsoft

    CERN Document Server

    Zachary, G Pascal

    2014-01-01

    Showstopper is the dramatic, inside story of the creation of Windows NT, told by Wall Street Journal reporter G. Pascal Zachary. Driven by the legendary Bruce Cutler, a picked band of software engineers sacrifices almost everything in their lives to build a new, stable, operating system aimed at giving Microsoft a platform for growth through the next decade of development in the computing business.Comparable in many ways to the Pulitzer Prize-winning book The Soul of a New Machine by Tracy Kidder, Showstopper gets deep inside the process of software development, the lives and motivations of co

  17. DMPD: Toll-like receptors regulation of viral infection and disease. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 18280610 Toll-like receptors regulation of viral infection and disease. Thompson JM...how Toll-like receptors regulation of viral infection and disease. PubmedID 18280610 Title Toll-like recepto...rs regulation of viral infection and disease. Authors Thompson JM, Iwasaki A. Pub

  18. Microhardness and microstructure evolution of TiB2 reinforced Inconel 625/TiB2 composite produced by selective laser melting

    Science.gov (United States)

    Zhang, Baicheng; Bi, Guijun; Nai, Sharon; Sun, Chen-nan; Wei, Jun

    2016-06-01

    In this study, micron-size TiB2 particles were utilized to reinforce Inconel 625 produced by selective laser melting. Exceptional microhardness 600-700 HV0.3 of the composite was obtained. In further investigation, the microstructure and mechanical properties of Inconel 625/TiB2 composite can be significantly influenced by addition of TiB2 particles during SLM. It was found that the long directional columnar grains observed from SLM-processed Inconel 625 were totally changed to fine dendritic matrix due to the addition of TiB2 particles. Moreover, with laser energy density (LED) of 1200 J/m, a Ti, Mo rich interface around TiB2 particles with fine thickness can be observed by FESEM and EDS. The microstructure evolution can be determined by different laser energy density (LED): under 1200 J/m, γ phase in dendrite grains; under 600 J/m, γ phase in combination of dendritic and acicular grains; under 400 J/m, γ phase acicular grains. Under optimized LED 1200 J/m, the dynamic nanohardness (8.62 GPa) and elastic modulus (167 GPa) of SLM-processed Inconel 625/TiB2 composite are higher compared with those of SLM-processed Inconel 625 (3.97 GPa and 135 GPa, respectively).

  19. T-DNA integration patterns in transgenic maize lines mediated by ...

    African Journals Online (AJOL)

    Jane

    2011-10-03

    Oct 3, 2011 ... locus can have profound effects on the level and stability of transgene ..... Thane N, Henke J, Wang T, Ruppert J, Shah N, Rotter K, Hodges J, ... Chia JM, Deragon JM, Estill JC, Fu Y, Jeddeloh JA, Han YJ, Lee H,. Li PH, Lisch ...

  20. Do Interlocutors or Conversation Topics Affect Migrants' Sense of Feeling Different When Switching Languages?

    Science.gov (United States)

    Panicacci, Alessandra; Dewaele, Jean-Marc

    2018-01-01

    A majority of multilinguals report feeling different when switching languages [Dewaele, J.-M. (2016). "Why do So Many Bi- and Multilinguals Feel Different When Switching Languages?" "International Journal of Multilingualism" 13 (1): 92-105; Panicacci, A., and J.-M. Dewaele. (2017). "'A Voice from Elsewhere': Acculturation,…

  1. Mathematical modelling and numerical solution of swelling of cartilaginous tissues. Part II: Mixed hybrid finite element solution

    NARCIS (Netherlands)

    Malakpoor, K.; Kaasschieter, E.F.; Huyghe, J.M.R.J.

    2007-01-01

    The swelling and shrinkage of biological tissues are modelled by a four-component mixture theory [J.M. Huyghe and J.D. Janssen, Int. J. Engng. Sci. 35 (1997) 793-802; K. Malakpoor, E.F. Kaasschieter and J.M. Huyghe, Mathematical modelling and numerical solution of swelling of cartilaginous tissues.

  2. Examining the Effects of Jyoti Meditation on Stress and the Moderating Role of Emotional Intelligence

    Science.gov (United States)

    Gutierrez, Daniel; Conley, Abigail H.; Young, Mark

    2016-01-01

    The authors examined whether Jyoti meditation (JM), a spiritually based meditation (Singh, 2012), influenced student counselors' (N = 60) level of stress and emotional intelligence (EI). Results from a randomized controlled trial and growth curve analysis provided a multilevel model in which JM reduced stress and EI moderated the effect.

  3. A Comparison of Joint Model and Fully Conditional Specification Imputation for Multilevel Missing Data

    Science.gov (United States)

    Mistler, Stephen A.; Enders, Craig K.

    2017-01-01

    Multiple imputation methods can generally be divided into two broad frameworks: joint model (JM) imputation and fully conditional specification (FCS) imputation. JM draws missing values simultaneously for all incomplete variables using a multivariate distribution, whereas FCS imputes variables one at a time from a series of univariate conditional…

  4. JM Maweu Indigenous Ecological Knowledge and Modern Western ...

    African Journals Online (AJOL)

    JM Maweu

    Indigenous knowledge is often dismissed as 'traditional and outdated', and hence irrelevant to ... What is more, there has been a consistent bias towards modern .... practices and representations that are developed and maintained by peoples with long histories of ..... “Indigenous Technical Knowledge: Analysis, Implications.

  5. Comparative analysis of root transcriptome profiles between drought-tolerant and susceptible wheat genotypes in response to water stress.

    Science.gov (United States)

    Hu, Ling; Xie, Yan; Fan, Shoujin; Wang, Zongshuai; Wang, Fahong; Zhang, Bin; Li, Haosheng; Song, Jie; Kong, Lingan

    2018-07-01

    Water deficit is one of the major factors limiting crop productivity worldwide. Plant roots play a key role in uptaking water, perceiving and transducing of water deficit signals to shoot. Although the mechanisms of drought-tolerance have been reported recently, the transcriptional regulatory network of wheat root response to water stress has not been fully understood. In this study, drought-tolerant cultivar JM-262 and susceptible cultivar LM-2 are planted to characterize the root transcriptional changes and physiological responses to water deficit. A total of 8197 drought tolerance-associated differentially expressed genes (DEGs) are identified, these genes are mainly mapped to carbon metabolism, flavonoid biosynthesis, and phytohormone signal transduction. The number and expression level of DEGs involved in antioxidative and antiosmotic stresses are more enhanced in JM-262 under water stress. Furthermore, we find the DEGs related to root development are much more induced in JM-262 in phytohormone signal transduction and carbon metabolism pathway. In conclusion, JM-262 may alleviate the damage of drought by producing more osmoprotectants, ROS scavengers, biomass and energy. Interestingly, hormone signaling and cross-talk probably play an important role in promoting JM-262 greater root systems to take up more water, higher capabilities to induce more drought-related DEGs and higher resisitance to oxidative stresse. Copyright © 2018 Elsevier B.V. All rights reserved.

  6. The Aged Microenvironment Influences Prostate Carcinogenesis

    Science.gov (United States)

    2008-12-01

    Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor. PLoS Biol 2008, 6:e301 31. Jeyapalan JC, Ferreira M...Sedivy JM, Herbig U: Accumulation of senescent cells in mitotic tissue of aging primates. Mech Ageing Dev 2007, 128:36-44 32. Jeyapalan JC, Sedivy JM

  7. Case report

    African Journals Online (AJOL)

    raoul

    28 avr. 2011 ... Spermatic cord sarcoma in adults. J Urol. 1978; 120: 301-305. This article on PubMed. 11. Romero Tenorio M, Farinas Varo JM, Baez Perez JM, Almaised J, Ramirez Chamorro R, and Beltran Ruiz-Hinestrosa M. Liposarcoma en la infancia: Aportacion de un case exceptional - Revision de la literatura.

  8. Participants in a medical applications meeting hosted by CERN Head of Medical Applications S. Myers with J. E. Celis, Chairman of the Policy Committee, European Cancer Organisation, President, European Association for Cancer Research and Prof. JM. Gago, President of Laboratório de Instrumentação e Física Experimental de Partículas (LIP) and Former Minister for Science, Technology and Higher Education of Portugal of the XVII Governo. Were also participating: CERN Life Science Adviser M. Dosanjh with U. Ringborg R. Lewensohn, A. Brahme, R. Moeckli, O. Jäkel and S. Pieck.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    Participants in a medical applications meeting hosted by CERN Head of Medical Applications S. Myers with J. E. Celis, Chairman of the Policy Committee, European Cancer Organisation, President, European Association for Cancer Research and Prof. JM. Gago, President of Laboratório de Instrumentação e Física Experimental de Partículas (LIP) and Former Minister for Science, Technology and Higher Education of Portugal of the XVII Governo. Were also participating: CERN Life Science Adviser M. Dosanjh with U. Ringborg R. Lewensohn, A. Brahme, R. Moeckli, O. Jäkel and S. Pieck.

  9. 20 fevrier 2012 - Le Vice-Président du Gouvernement Wallon et Ministre du Développement durable et de la Fonction Publique en charge de l’Energie du Logement et de la Recherche J.-M. Nollet, Royaume de Belgique, visite la salle de contrôle de CMS au Point 5, la caverne expérimentale CMS et le hall de tests des aimants supraconducteurs du LHC. Les chefs de département T. Lagrange et F. Hemmer accompagnent la délégation. L. Walckiers guide la visite SM18.

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    20 fevrier 2012 - Le Vice-Président du Gouvernement Wallon et Ministre du Développement durable et de la Fonction Publique en charge de l’Energie du Logement et de la Recherche J.-M. Nollet, Royaume de Belgique, visite la salle de contrôle de CMS au Point 5, la caverne expérimentale CMS et le hall de tests des aimants supraconducteurs du LHC. Les chefs de département T. Lagrange et F. Hemmer accompagnent la délégation. L. Walckiers guide la visite SM18.

  10. Enterobacter muelleri sp. nov., isolated from the rhizosphere of Zea mays.

    Science.gov (United States)

    Kämpfer, Peter; McInroy, John A; Glaeser, Stefanie P

    2015-11-01

    A beige-pigmented, oxidase-negative bacterial strain (JM-458T), isolated from a rhizosphere sample, was studied using a polyphasic taxonomic approach. Cells of the isolate were rod-shaped and stained Gram-negative. A comparison of the 16S rRNA gene sequence of strain JM-458T with sequences of the type strains of closely related species of the genus Enterobacter showed that it shared highest sequence similarity with Enterobacter mori (98.7 %), Enterobacter hormaechei (98.3 %), Enterobacter cloacae subsp. dissolvens, Enterobacter ludwigii and Enterobacter asburiae (all 98.2 %). 16S rRNA gene sequence similarities to all other Enterobacter species were below 98 %. Multilocus sequence analysis based on concatenated partial rpoB, gyrB, infB and atpD gene sequences showed a clear distinction of strain JM-458T from its closest related type strains. The fatty acid profile of the strain consisted of C16 : 0, C17 : 0 cyclo, iso-C15 : 0 2-OH/C16 : 1ω7c and C18 : 1ω7c as major components. DNA-DNA hybridizations between strain JM-458T and the type strains of E. mori, E. hormaechei and E. ludwigii resulted in relatedness values of 29 % (reciprocal 25 %), 24 % (reciprocal 43 %) and 16 % (reciprocal 17 %), respectively. DNA-DNA hybridization results together with multilocus sequence analysis results and differential biochemical and chemotaxonomic properties showed that strain JM-458T represents a novel species of the genus Enterobacter, for which the name Enterobacter muelleri sp. nov. is proposed. The type strain is JM-458T ( = DSM 29346T = CIP 110826T = LMG 28480T = CCM 8546T).

  11. Measurement of M. luteus endonuclease-sensitive lesions by alkaline elution

    Energy Technology Data Exchange (ETDEWEB)

    Fornace, Jr, A J [National Cancer Inst., Bethesda, MD (USA). Lab. for Experimental Pathology

    1982-01-01

    The UV-endonuclease approach to detect DNA damage has been combined with the alkaline elution technique with a resultant marked increase in sensitivity compared to the conventional method using alkaline sedimentation. DNA from UV-irradiated cells was digested on an inert filter with an extract from Micrococcus luteus and then analyzed by alkaline elution. Endonuclease-sensitive sites (endo-sites) were measured after doses of 0.08-0.7 Jm/sup -2/ of UV-radiation. An estimate of endo-site production with UV radiation, 0.27 endo-sites/10/sup 8/ daltons of DNA/0.1 Jm/sup -2/, was similar to that usually seen at higher doses by others. With repair incubation, approx. 50% of the endo-sites were removed in 4 h by normal human fibroblasts after 0.2 or 0.4 Jm/sup -2/, no appreciable repair was seen in xeroderma pigmentosum fibroblasts from complementation group A after 24 h of repair incubation. No photoreaction of UV damage due to 0.4 Jm/sup -2/ was detected in normal human fibroblasts.

  12. Measurement of M. luteus endonuclease-sensitive lesions by alkaline elution

    International Nuclear Information System (INIS)

    Fornace, A.J. Jr.

    1982-01-01

    The UV-endonuclease approach to detect DNA damage has been combined with the alkaline elution technique with a resultant marked increase in sensitivity compared to the conventional method using alkaline sedimentation. DNA from UV-irradiated cells was digested on an inert filter with an extract from Micrococcus luteus and then analyzed by alkaline elution. Endonuclease-sensitive sites (endo-sites) were measured after doses of 0.08-0.7 Jm -2 of UV-radiation. An estimate of endo-site production with UV radiation, 0.27 endo-sites/10 8 daltons of DNA/0.1 Jm -2 , was similar to that usually seen at higher doses by others. With repair incubation, approx. 50% of the endo-sites were removed in 4 h by normal human fibroblasts after 0.2 or 0.4 Jm -2 , no appreciable repair was seen in xeroderma pigmentosum fibroblasts from complementation group A after 24 h of repair incubation. No photoreaction of UV damage due to 0.4 Jm -2 was detected in normal human fibroblasts. (orig./AJ)

  13. Applications of an anti-symmetry loop algebra and its expanding forms

    International Nuclear Information System (INIS)

    Zhang Yufeng; Yan Qingyou

    2004-01-01

    Constructing an anti-symmetry subalgebra A-tilde 2 of loop algebra A-tilde 2 gives the well-known Jaulent-Miodek (JM) hierarchy, the JM equation and its new Lax pair. Further, the Darboux transformation of the JM equation is deduced by anstaz method. By making use of a high-order loop algebra and Tu scheme, an expanding integrable model of the JM hierarchy is obtained. A direct expansion A-macron 2 * of loop algebra A-tilde 2 by considering the definition of Lie algebra is presented, which is used to establish two isospectral problems. It follows that corresponding two new integrable systems are engendered, which possess bi-Hamiltonian structures, respectively. Furthermore, a scalar transformation is applied to turn the loop algebra A-bar 2 * into its equivalent subalgebra A-tilde 1 of loop algebra A-tilde 1 . With the help of A-tilde 1 , another new high-order loop algebra G-bar is constructed, which is used to obtain an expanding integrable model of one of two integrable systems presented

  14. Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration

    Science.gov (United States)

    Zwilling, Daniel; Huang, Shao-Yi; Sathyasaikumar, Korrapati V.; Notarangelo, Francesca M.; Guidetti, Paolo; Wu, Hui-Qiu; Lee, Jason; Truong, Jennifer; Andrews-Zwilling, Yaisa; Hsieh, Eric W.; Louie, Jamie Y.; Wu, Tiffany; Scearce-Levie, Kimberly; Patrick, Christina; Adame, Anthony; Giorgini, Flaviano; Moussaoui, Saliha; Laue, Grit; Rassoulpour, Arash; Flik, Gunnar; Huang, Yadong; Muchowski, Joseph M.; Masliah, Eliezer; Schwarcz, Robert; Muchowski, Paul J.

    2011-01-01

    SUMMARY Metabolites in the kynurenine pathway of tryptophan degradation are thought to play an important role in neurodegenerative disorders such as Alzheimer’s disease and Huntington’s disease. Metabolites that cause glutamate receptor-mediated excitotoxicity and free radical formation are elevated in the blood and vulnerable brain regions in these diseases, while levels of the neuroprotective metabolite kynurenic acid are often decreased. Here we describe the synthesis and characterization of JM6, a novel small-molecule pro-drug inhibitor of kynurenine 3-monooxygenase (KMO). JM6 raises kynurenic acid and reduces extracellular glutamate in the brain after chronic oral administration by inhibiting KMO in blood. In a transgenic mouse model of Alzheimer’s disease, JM6 prevented spatial memory deficits, anxiety-related behavior, and synaptic loss. JM6 also extended life span, prevented synaptic loss, and decreased microglial activation in a mouse model of Huntington’s disease. These findings support a critical link between blood cells and neurodegeneration that is mediated by KMO and the kynurenine pathway. PMID:21640374

  15. Ultraviolet induced lysosome activity in corneal epithelium

    International Nuclear Information System (INIS)

    Cullen, A.P.

    1980-01-01

    A 5.000 W Xe-Hg high pressure lamp and a double monochromator were used to produce a 3.3 nm half-bandpass ultraviolet radiation at 295 nm. Pigmented rabbit eyes were irradiated with radiant exposures from 140 Jm -2 to 10.000 Jm -2 and evaluated by slit-lamp biomicroscopy, light and electron microscopy. Corneal threshold (Hsub(c) was 200 Jm -2 and lens threshold (Hsub(L)) was 7.500 Jm -2 . The most repeatable and reliable corneal response to these levels of UV was the development of corneal epithelial granules. Histological changes included a loss of superficial epithelial cells and selective UV induced autolysis of the wing cells. It is suggested that the biomicroscopically observed granules are the clinical manifestation of the secondary lysosomes revealed by light and electron microscopy. It is proposed that UV breaks down the primary lysosome membranes to release hydrolytic enzymes which in turn form the secondary lysosomes during autolysis. Extreme levels of radiant exposure at 295 nm result in indiscriminate destruction of all layers of the corneal epithelium, but the posterior cornea was spared. (orig.) [de

  16. Strain Effects on Properties of Phosphorene and Phosphorene Nanoribbons: a DFT and Tight Binding Study

    Science.gov (United States)

    Zhang, Ruo-Yu; Zheng, Ji-Ming; Jiang, Zhen-Yi

    2018-01-01

    Not Available Supported by the National Natural Science Foundation of China under Grant Nos 51572219 and 11447030, the Natural Science Foundation of Shaanxi Province of China under Grant Nos 2014JM2-1008 and 2015JM1018, and the State Key Laboratory of Transient Optics and Photonics Technology 2015 Annual Open Fund under Grant No SKLST200915.

  17. Microstructure and mechanical properties of metal/oxide and metal/silicide interfaces

    International Nuclear Information System (INIS)

    Shaw, L.; Miracle, D.; Abbaschian, R.

    1995-01-01

    Fracture energies of Al 2 O 3 /Nb interfaces and MoSi 2 /Nb interfaces with and without Al 2 O 3 coating were measured using sandwich-type chevron-notched specimens. The relations between the mechanical properties, microstructures, types of bonds at the interface and processing routes were explored. The fracture energy of the Al 2 O 3 /Nb interface was determined to be 9 J/m 2 and changed to 16 J/m 2 when Nb was pre-oxidized before the formation of the Al 2 O 3 /Nb interface. The fracture energy of the MoSi 2 /Nb interface could not be determined directly because of the formation of the interfacial compounds. However, the fracture energy at the MoSi 2 /Nb interfacial region was found to depend on the interfacial bond strength, roughness of interfaces and microstructure of interfacial compounds. The interfacial fracture energies of Al 2 O 3 with silicides, MoSi 2 , Nb 5 Si 3 , or (Nb, Mo)Si 2 were estimated to be about 16 J/m 2 , while the interfacial fracture energies between two silicides or between Nb and a silicide were larger than 34 J/m 2 . The measured fracture energies between two silicides or between Nb and a silicide were larger than 34 J/m 2 . The measured fracture energies of the various interfaces are discussed in terms of the interfacial microstructures and types of bonds at the interfaces

  18. Cultivable endophytic bacteria from leaf bases of Agave tequilana and their role as plant growth promoters.

    Science.gov (United States)

    Martínez-Rodríguez, Julia del C; De la Mora-Amutio, Marcela; Plascencia-Correa, Luis A; Audelo-Regalado, Esmeralda; Guardado, Francisco R; Hernández-Sánchez, Elías; Peña-Ramírez, Yuri J; Escalante, Adelfo; Beltrán-García, Miguel J; Ogura, Tetsuya

    2014-01-01

    Agave tequilana Weber var. 'Azul' is grown for the production of tequila, inulin and syrup. Diverse bacteria inhabit plant tissues and play a crucial role for plant health and growth. In this study culturable endophytic bacteria were extracted from leaf bases of 100 healthy Agave tequilana plants. In plant tissue bacteria occurred at mean population densities of 3 million CFU/g of fresh plant tissue. Three hundred endophytic strains were isolated and 16s rDNA sequences grouped the bacteria into eight different taxa that shared high homology with other known sequences. Bacterial endophytes were identified as Acinectobacter sp., A. baumanii, A. bereziniae, Cronobacter sakazakii, Enterobacter hormaechei, Bacillus sp. Klebsiella oxytoca, Pseudomonas sp., Enterococcus casseliflavus, Leuconostoc mesenteroides subsp. mesenteroides and Gluconobacter oxydans. Isolates were confirmed to be plant growth promoting bacteria (PGPB) by their capacities for nitrogen fixation, auxin production, phosphate solubilization, or antagonism against Fusarium oxysporum AC132. E. casseliflavus JM47 and K. oxytoca JM26 secreted the highest concentrations of IAA. The endophyte Acinectobacter sp. JM58 exhibited the maximum values for nitrogen fixation and phosphate solubilization index (PSI). Inhibition of fungi was found in Pseudomonas sp. JM9p and K. oxytoca JM26. Bacterial endophytes show promise for use as bio-inoculants for agave cultivation. Use of endophytes to enhance cultivation of agave may be particularly important for plants produced by micropropagation techniques, where native endophytes may have been lost.

  19. Cultivable endophytic bacteria from leaf bases of Agave tequilana and their role as plant growth promoters

    Directory of Open Access Journals (Sweden)

    Julia del C. Martínez-Rodríguez

    2014-12-01

    Full Text Available Agave tequilana Weber var. 'Azul' is grown for the production of tequila, inulin and syrup. Diverse bacteria inhabit plant tissues and play a crucial role for plant health and growth. In this study culturable endophytic bacteria were extracted from leaf bases of 100 healthy Agave tequilana plants. In plant tissue bacteria occurred at mean population densities of 3 million CFU/g of fresh plant tissue. Three hundred endophytic strains were isolated and 16s rDNA sequences grouped the bacteria into eight different taxa that shared high homology with other known sequences. Bacterial endophytes were identified as Acinectobacter sp., A. baumanii, A. bereziniae, Cronobacter sakazakii, Enterobacter hormaechei, Bacillus sp. Klebsiella oxytoca, Pseudomonas sp., Enterococcus casseliflavus, Leuconostoc mesenteroides subsp. mesenteroides and Gluconobacter oxydans. Isolates were confirmed to be plant growth promoting bacteria (PGPB by their capacities for nitrogen fixation, auxin production, phosphate solubilization, or antagonism against Fusarium oxysporum AC132. E. casseliflavus JM47 and K. oxytoca JM26 secreted the highest concentrations of IAA. The endophyte Acinectobacter sp. JM58 exhibited the maximum values for nitrogen fixation and phosphate solubilization index (PSI. Inhibition of fungi was found in Pseudomonas sp. JM9p and K. oxytoca JM26. Bacterial endophytes show promise for use as bio-inoculants for agave cultivation. Use of endophytes to enhance cultivation of agave may be particularly important for plants produced by micropropagation techniques, where native endophytes may have been lost.

  20. Hotell 'Bernhard' Otepääl. Otepää aedlinn, Kolga tee 22a / Andres Lunge

    Index Scriptorium Estoniae

    Lunge, Andres

    1998-01-01

    Otepää aedlinnas asuva U. Tiirmaa poolt kuuekümnendatel projekteeritud Tartu Katseremonditehase puhkebaasi rekonstrueerimine. Kavandati uus peasissepääs, täiendav tubadekorrus, restoran, vastuvõtufuajee jm. ning juurdeehitusena osaliselt maaalune lisakorpus konverentsisaali jm. ruumidega. Tellija: AS Regel. Projekteerija: Tareke Projekt OÜ. Arhitekt Andres Lunge. Sisekujundaja Taisi Kadarik. Ehitus: AS Regel, 1996-1998. Projekt 1995, 1998, valmis 1998

  1. AcEST: DK949288 [AcEST

    Lifescience Database Archive (English)

    Full Text Available e dehydrogenase (Fragment) OS=Arab... 50 7e-05 tr|Q84JM5|Q84JM5_IPONI Angustifolia OS=Ipomoea nil GN=IAN PE=... 0.015 tr|B6U1W6|B6U1W6_MAIZE Angustifolia OS=Zea mays PE=2 SV=1 42 0.015 tr|A3C6

  2. Exploring Diverse Effects of Four Types of Mobility on University Entrepreneurship

    Directory of Open Access Journals (Sweden)

    Satoko Yasuda

    2016-12-01

    Full Text Available This study explores the mechanism by which mobility influences university entrepreneurship through an empirical analysis of Japanese scientists working for the University of Tokyo. It presents theory-driven typology of mobility and applies it to the knowledge-transfer context.  First, this paper subdivides previously-studied mobility into four types – job mobility (JM, sector mobility (SM, international mobility (IM, and the educational background mobility (EBM. Then, it empirically shows that both JM and IM have positive and significant correlation with university entrepreneurship, whereas neither SM nor EBM does. Based on the result, this study discusses that JM and IM accelerate the formation of skills necessary for the commercialization of university research; however, SM and EBM may have no impact on it.

  3. First report of a complete genome sequence for a begomovirus infecting Jatropha gossypifolia in the Americas.

    Science.gov (United States)

    Simmonds-Gordon, R N; Collins-Fairclough, A M; Stewart, C S; Roye, M E

    2014-10-01

    Jatropha gossypifolia is a weed that is commonly found with yellow mosaic symptoms growing along the roadside and in close proximity to cultivated crops in many farming communities in Jamaica. For the first time, the complete genome sequence of a new begomovirus, designated jatropha mosaic virus-[Jamaica:Spanish Town:2004] (JMV-[JM:ST:04]), was determined from field-infected J. gossypifolia in the western hemisphere. DNA-A nucleotide sequence comparisons showed closest identity (84 %) to two tobacco-infecting viruses from Cuba, tobacco mottle leaf curl virus-[Cuba:Sancti Spiritus:03] (TbMoLCV-[CU:SS:03]) and tobacco leaf curl Cuba virus-[Cuba:Taguasco:2005] (TbLCuCUV-[CU:Tag:05]), and two weed-infecting viruses from Cuba and Jamaica, Rhynchosia rugose golden mosaic virus-[Cuba:Camaguey:171:2009] (RhRGMV- [CU:Cam:171:09]) and Wissadula golden mosaic St. Thomas virus-[Jamaica:Albion:2005] (WGMSTV-[JM:Alb:05]). Phylogenetic analysis revealed that JMV-[JM:ST:04] is most closely related to tobacco and tomato viruses from Cuba and WGMSTV-[JM:Alb:05], a common malvaceous-weed-infecting virus from eastern Jamaica, and that it is distinct from begomoviruses infecting Jatropha species in India and Nigeria.

  4. Ultraviolet induced lysosome activity in corneal epithelium

    Energy Technology Data Exchange (ETDEWEB)

    Cullen, A.P.

    1980-01-01

    A 5.000 W Xe-Hg high pressure lamp and a double monochromator were used to produce a 3.3 nm half-bandpass ultraviolet radiation at 295 nm. Pigmented rabbit eyes were irradiated with radiant exposures from 140 Jm/sup -2/ to 10.000 Jm/sup -2/ and evaluated by slit-lamp biomicroscopy, light and electron microscopy. Corneal threshold (Hsub(c) was 200 Jm/sup -2/ and lens threshold (Hsub(L)) was 7.500 Jm/sup -2/. The most repeatable and reliable corneal response to these levels of UV was the development of corneal epithelial granules. Histological changes included a loss of superficial epithelial cells and selective UV induced autolysis of the wing cells. It is suggested that the biomicroscopically observed granules are the clinical manifestation of the secondary lysosomes revealed by light and electron microscopy. It is proposed that UV breaks down the primary lysosome membranes to release hydrolytic enzymes which in turn form the secondary lysosomes during autolysis. Extreme levels of radiant exposure at 295 nm result in indiscriminate destruction of all layers of the corneal epithelium, but the posterior cornea was spared.

  5. Mixed infection of Sida jamaicensis in Jamaica reveals the presence of three recombinant begomovirus DNA A components.

    Science.gov (United States)

    Stewart, Cheryl; Kon, Tatsuya; Rojas, Maria; Graham, André; Martin, Darren; Gilbertson, Robert; Roye, Marcia

    2014-09-01

    Begomoviruses impose serious constraints on agriculture throughout the temperate, tropical and subtropical regions. Previously, we characterised a sida golden yellow vein virus isolate, SiGYVV-[JM:Lig2:08] (HQ009519-20) from a symptomatic Sida jamaicensis plant. With the aim of establishing whether it was hosting a mixed infection that could facilitate recombination, PCR-RFLP was done on DNA extracted from this plant, and the results suggested the presence of two additional genetically distinct DNA-A molecules. Sequence analysis of these two DNA-A molecules (relying on BLAST searches and the CLUSTAL V algorithm within the DNASTAR MegAlign module) revealed that they belonged to novel species, and we have tentatively named these viruses sida golden mosaic Braco virus-[Jamaica:Liguanea:2008] and sida golden mosaic Liguanea virus-[Jamaica:1:2008]. Using RDP4 (recombination detection program), we determined that all three viruses were recombinant, with bases ~10 to ~440 of both SiGMLigV-[JM:Lig:08] and SiGYVV-[JM:Lig2:08] having been derived from a relative of SiGMBV-[JM:Lig:08] (P<2.070×10(-7) for all seven of the recombination detection methods). SiGMBV-[JM:Lig:08] was itself a product of recombination, deriving bases ~490-1195 from a virus that was ~92% similar to malvastrum yellow mosaic Helshire virus. Phylogenetically, these DNA-A components are most closely related to those of malvaceous weed-infecting begomoviruses from Jamaica, Cuba, Florida and Mexico. The SiGMBV DNA-A was able to elicit symptomatic infection in N. benthamiana.

  6. A New Auto-Baecklund Transformation and Two-Soliton Solution for (3+1)-Dimensional Jimbo-Miwa Equation

    International Nuclear Information System (INIS)

    Liu Chunping; Zhou Ling

    2011-01-01

    By improving the extended homogeneous balance method, a general method is suggested to derive a new auto-Baecklund transformation (BT) for (3+1)-Dimensional Jimbo-Miwa (JM) equation. The auto-BT obtained by using our method only involves one quadratic homogeneity equation written as a bilinear equation. Based on the auto-BT, two-soliton solution of the (3+1)-Dimensional JM equation is obtained. (general)

  7. Molecular characterization and experimental host range of an isolate of Wissadula golden mosaic St. Thomas virus.

    Science.gov (United States)

    Collins, A M; Mujaddad-ur-Rehman, Malik; Brown, J K; Reddy, C; Wang, A; Fondong, V; Roye, M E

    2009-12-01

    Partial genome segments of a begomovirus were previously amplified from Wissadula amplissima exhibiting yellow-mosaic and leaf-curl symptoms in the parish of St. Thomas, Jamaica and this isolate assigned to a tentative begomovirus species, Wissadula golden mosaic St. Thomas virus. To clone the complete genome of this isolate of Wissadula golden mosaic St. Thomas virus, abutting primers were designed to PCR amplify its full-length DNA-A and DNA-B components. Sequence analysis of the complete begomovirus genome obtained, confirmed that it belongs to a distinct begomovirus species and this isolate was named Wissadula golden mosaic St. Thomas virus-[Jamaica:Albion:2005] (WGMSTV-[JM:Alb:05]). The genome of WGMSTV-[JM:Alb:05] is organized similar to that of other bipartite Western Hemisphere begomoviruses. Phylogenetic analyses placed the genome components of WGMSTV-[JM:Alb:05] in the Abutilon mosaic virus clade and showed that the DNA-A component is most closely related to four begomovirus species from Cuba, Tobacco leaf curl Cuba virus, Tobacco leaf rugose virus, Tobacco mottle leaf curl virus, and Tomato yellow distortion leaf virus. The putative Rep-binding-site motif in the common region of WGMSTV-[JM:Alb:05] was observed to be identical to that of Chino del tomate virus-Tomato [Mexico:Sinaloa:1983], Sida yellow mosaic Yucatan virus-[Mexico:Yucatan:2005], and Tomato leaf curl Sinaloa virus-[Nicaragua:Santa Lucia], suggesting that WGMSTV-[JM:Alb:05] is capable of forming viable pseudo-recombinants with these begomoviruses, but not with other members of the Abutilon mosaic virus clade. Biolistic inoculation of test plant species with partial dimers of the WGMSTV-[JM:Alb:05] DNA-A and DNA-B components showed that the virus was infectious to Nicotiana benthamiana and W. amplissima and the cultivated species Phaseolus vulgaris (kidney bean) and Lycopersicon esculentum (tomato). Infected W. amplissima plants developed symptoms similar to symptoms observed under field

  8. Dicty_cDB: SSL385 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available C37A2, complete sequence. 38 0.049 3 BZ347525 |BZ347525.1 hm84h07.b1 WGS-SbicolorF (JM107 adapted methyl filter...-SbicolorF (JM107 adapted methyl filtered) Sorghum bicolor genomic clone ho57b09 ..._Ba0020C03 5', genomic survey sequence. 42 0.33 2 BZ366117 |BZ366117.1 ic94g05.g1 WGS-SbicolorF (JM107 adapted methyl filter...in ordered pieces. 44 0.88 1 BZ626058 |BZ626058.1 ih42h02.b1 WGS-SbicolorF (DH5a methyl filter...07.g1 WGS-SbicolorF (DH5a methyl filtered) Sorghum bicolor genomic clone ii21a07, DNA sequence. 38 3.0 2 dna

  9. The molecular characterisation of a Sida-infecting begomovirus from Jamaica.

    Science.gov (United States)

    Stewart, Cheryl; Kon, Tatsuya; Rojas, Maria; Graham, André; Martin, Darren; Gilbertson, Robert; Roye, Marcia

    2014-02-01

    The complete DNA sequence of both genome components of a new begomovirus (Sida golden mosaic Buckup virus-[Jamaica:St. Elizabeth:2004]; SiGMBuV-[JM:SE:04]) was determined from a field-infected Sida sp. sample from Buckup, St. Elizabeth, Jamaica. Phylogenetically, both genome components of SiGMBuV-[JM:SE:04] are most closely related to malvaceous weed-infecting Floridian and Mexican begomoviruses. Its DNA-B is a recombinant molecule, the majority of which was derived from a virus resembling Sida yellow mosaic Yucatan virus-[Mexico:Yucatan:2005] (SiYMYuV-[MX:Yuc:05]), while nucleotides 43-342 were derived from a virus resembling Sida golden mosaic virus-[United States of America:Florida] (SiGMV-[US:Flo]). Symptomatic infectivity of our cloned SiGMBuV-[JM:SE:04] components was confirmed in Nicotiana benthamiana.

  10. Liminality in J.M. Coetzee’s later experimental texts

    Directory of Open Access Journals (Sweden)

    Annemie Grobler

    2015-07-01

    Full Text Available Postcoloniality, which is essentially concerned with the transition and transgression of boundaries and borders, contextualises and defines liminality as an ephemeral concept that eludes pinning down. Liminality is continually involved in a dual process of evolving and subverting: dynamic in the sense of promoting the centre, but subversive in its destabilisation of the previous status quo. In the more recent novels by Coetzee (Slow man, Diary of a bad year, Elizabeth Costello, themes that are especially acute in highlighting the subversive nature of liminality emerge repeatedly: the threshold, death, proliferation and imitation. The problem investigated is: how is the concept of liminality developed in these novels? An examination of these novels in terms of the above-mentioned themes and various conceptual and theoretical elements shows that Coetzee encourages the reader to assume a liminal status, not only as reader of the texts but also in relation to contemporary reality. It is concluded that Coetzee uses certain themes that promote liminality, often in a subversive and deconstructive manner, to inform the reader and, thus, influence him or her to effect change in the contemporary world.

  11. Male-male relationships in J.M. Coetzee’s Disgrace

    Directory of Open Access Journals (Sweden)

    M. Crous

    2006-07-01

    Full Text Available Kochin (2002:8 makes the following interesting observation regarding the life of the main character, David Lurie, in Coetzee’s novel, “Disgrace” (1999, and his observation will be explored in detail when analysing the novel, and in particular the presentation of masculinities: “Lurie has no relationship of depth with men. His one effort is with Isaacs, Melanie’s father, and seems to be more of a quest for the sources of Melanie’s beauty than the expression of a desire for friendship with a man.” The focus of my investigation is on male-male relationships and the way in which they impact on the other characters in the novel. What contribution does the novel make to the debate on masculinity within the context of South African literary studies?

  12. AcEST: BP916224 [AcEST

    Lifescience Database Archive (English)

    Full Text Available 70 5e-11 tr|A3C6S4|A3C6S4_ORYSJ Putative uncharacterized protein OS=Oryza... 70 5e-11 tr|B6U1W6|B6U1W6_MAIZE Angus...ent) OS=Arab... 65 2e-09 tr|Q84JM5|Q84JM5_IPONI Angustifolia OS=Ipomoea nil GN=IA

  13. AcEST: BP915041 [AcEST

    Lifescience Database Archive (English)

    Full Text Available . 172 1e-41 tr|B6U1W6|B6U1W6_MAIZE Angustifolia OS=Zea mays PE=2 SV=1 170 6e-41 tr|Q948X7|Q948X7_ARATH C-ter...YQ6_ARATH Putative uncharacterized protein (Putativ... 166 1e-39 tr|Q84JM5|Q84JM5_IPONI Angustifolia OS=Ipom

  14. Sealpool nukkude orgu asub pop-voodoo / Aleksander Tsapov

    Index Scriptorium Estoniae

    Tsapov, Aleksander

    2006-01-01

    Ekstsentrilisest disainist. Raffaele Ianello ja Irene van Gesteli noa- ja hambaorgihoidjad, Philippe Starcki ja Critz Campbelli tugitool-valgustid, August de Martinville'i papist jahitrofee, Sebastian E. partlamp, Isabelle Leijni keraamilised kiivrid, Harry Alleni hoiupõrsas jm. High-tech kodusisustuse näiteid: Jackie Shapiro disainitud taldrikud, Frank Gehry sofa, Ingo Maureri Campari Soda lamp, Sonya Chow siilvalgusti, Mathias Bengtssoni (sünd. 1971) alumiiniumtool, Piet Houtenbosi õlilambid jm.

  15. Explicit Solutions for the (2 + 1-Dimensional Jaulent–Miodek Equation Using the Integrating Factors Method in an Unbounded Domain

    Directory of Open Access Journals (Sweden)

    Rahma Sadat

    2018-03-01

    Full Text Available In this work, we prove that the integrating factors can be used as a reduction method. Analytical solutions of the Jaulent–Miodek (JM equation are obtained using integrating factors as an extension of a recent work where, through hidden symmetries, the JM was reduced to ordinary differential equations (ODEs. Some of these ODEs had no quadrature. We here derive several new solutions for these non-solvable ODEs.

  16. A Measurement of Charged and Neutral Elementary Particles Emitted from Antiproton Annihilation at Rest in Heavy Nuclei

    Science.gov (United States)

    1989-06-15

    The Pennsylvania State University 2 1. Smith. G.A.: The elementary structure of matter. Richard, J.-M.. College of Science Aslanides . E., Boccara. N...1987) J.-M. Richard, E. Aslanides and N. Boccara, Springer p. 149. ~ il - c r D f C Z o C- S C W 3: c x 2 0 a : at~ a ,a TC jc g, cm m, 0 a, w 0 0C C

  17. Elucidating the weak protein-protein interaction mechanisms behind the liquid-liquid phase separation of a mAb solution by different types of additives.

    Science.gov (United States)

    Wu, Guoliang; Wang, Shujing; Tian, Zhou; Zhang, Ning; Sheng, Han; Dai, Weiguo; Qian, Feng

    2017-11-01

    Liquid-liquid phase separation (LLPS) has long been observed during the physical stability investigation of therapeutic protein formulations. The buffer conditions and the presence of various excipients are thought to play important roles in the formulation development of monoclonal antibodies (mAbs). In this study, the effects of several small-molecule excipients (histidine, alanine, glycine, sodium phosphate, sodium chloride, sorbitol and sucrose) with diverse physical-chemical properties on LLPS of a model IgG1 (JM2) solutions were investigated by multiple techniques, including UV-vis spectroscopy, circular dichroism, differential scanning calorimetry/fluorimetry, size exclusion chromatography and dynamic light scattering. The LLPS of JM2 was confirmed to be a thermodynamic equilibrium process with no structural changes or irreversible aggregation of proteins. Phase diagrams of various JM2 formulations were constructed, suggesting that the phase behavior of JM2 was dependent on the solution pH, ionic strength and the presence of other excipients such as glycine, alanine, sorbitol and sucrose. Furthermore, we demonstrated that for this mAb, the interaction parameter (k D ) determined at low protein concentration appeared to be a good predictor for the occurrence of LLPS at high concentration. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Does distal tibiofibular joint mobilization decrease limitation of ankle dorsiflexion?

    Science.gov (United States)

    Fujii, Misaki; Suzuki, Daisuke; Uchiyama, Eiichi; Muraki, Takayuki; Teramoto, Atsushi; Aoki, Mitsuhiro; Miyamoto, Shigenori

    2010-02-01

    Limitation of ankle motion is in many cases treated by joint mobilization (JM), a kind of manual physical therapy technique. Until now, the JM approach has mainly focused on the talocrural joint, with less attention to the distal tibiofibular joint. We applied cyclic loading to the lateral malleolus as in JM in order to clarify the relationship between the dorsiflexion angle and the excursion of the lateral malleolus. Seven normal, fresh-frozen cadaver legs were used. To each specimen, cyclic loading with a 30N force was applied 1000 times to the lateral malleolus at a speed of 15N/s. The displacement of the lateral malleolus was measured with a magnetic tracking system. The maximum dorsiflexion angle was measured before and after cyclic loading. After the first 100 and 1000 times of cyclic loading, the tibia was displaced 0.44+/-0.30mm and 0.75+/-0.36mm, respectively, and the fibula was displaced 0.44+/-0.28mm and 0.92+/-0.39mm, respectively. The average dorsiflexion angle increased from 14.36+/-7.51 degrees to 16.74+/-7.21 degrees after cyclic loading (Pankle dorsiflexion. These results suggest that tibiofibular JM would be effective for limitation of ankle dorsiflexion.

  19. Magnon-mediated Dzyaloshinskii-Moriya torque in homogeneous ferromagnets

    KAUST Repository

    Manchon, Aurelien

    2014-12-01

    In thin magnetic layers with structural inversion asymmetry and spin-orbit coupling, the Dzyaloshinskii-Moriya interaction arises at the interface. When a spin-wave current jm flows in a system with a homogeneous magnetization m, this interaction produces an effective fieldlike torque of the form TFLm×(z×jm) as well as a dampinglike torque, TDLm×[(z×jm)×m], the latter only in the presence of spin-wave relaxation (z is normal to the interface). These torques mediated by the magnon flow can reorient the time-averaged magnetization direction and display a number of similarities with the torques arising from the electron flow in a magnetic two-dimensional electron gas with Rashba spin-orbit coupling. This magnon-mediated spin-orbit torque can be efficient in the case of magnons driven by a thermal gradient.

  20. Carbon Nanotubes’ Effect on Mitochondrial Oxygen Flux Dynamics: Polarography Experimental Study and Machine Learning Models using Star Graph Trace Invariants of Raman Spectra

    Directory of Open Access Journals (Sweden)

    Michael González-Durruthy

    2017-11-01

    Full Text Available This study presents the impact of carbon nanotubes (CNTs on mitochondrial oxygen mass flux (Jm under three experimental conditions. New experimental results and a new methodology are reported for the first time and they are based on CNT Raman spectra star graph transform (spectral moments and perturbation theory. The experimental measures of Jm showed that no tested CNT family can inhibit the oxygen consumption profiles of mitochondria. The best model for the prediction of Jm for other CNTs was provided by random forest using eight features, obtaining test R-squared (R2 of 0.863 and test root-mean-square error (RMSE of 0.0461. The results demonstrate the capability of encoding CNT information into spectral moments of the Raman star graphs (SG transform with a potential applicability as predictive tools in nanotechnology and material risk assessments.

  1. Modifying factors of the cellular concentration of photolyase molecules in Saccharomyces cerevisiae

    International Nuclear Information System (INIS)

    Fukui, A.; Laskowski, W.

    1984-01-01

    The effects of preillumination with photoreactivating light flashes before UV-irradiation on the number of photoreactivable complexes consisting of UV-induced DNA-damages and active photolyase molecules (Nsub(PREact), on the fluence decrements ΔDsub(PRE), that are obtained from two UV-survival curves without and with 1 flash photoreactivation and proportional to Nsub(PREact) were determined in haploid Saccharomyces cerevisiae cells. ΔDsub(PRE) increased by preillumination from 0.115 J m -2 to 0.460 Jm -2 and from 0.376 Jm -2 to 0.494 Jm -2 in cells in logarithmic growth phase and in stationary growth phase, respectively. ΔDsub(PRE) in log-cells that were preilluminated before and after resuspension in buffer at 40 0 C for 60 min was larger than ΔDsub(PRE) in log-cells preilluminated only after resuspension in buffer. (author)

  2. Tuning of nanodiamond particles’ optical properties by structural defects and surface modifications: DFT modelling

    Czech Academy of Sciences Publication Activity Database

    Kratochvílová, Irena; Kovalenko, Alexander; Fendrych, František; Petráková, Vladimíra; Záliš, Stanislav; Nesladek, M.

    2011-01-01

    Roč. 21, č. 45 (2011), s. 18248-18255 ISSN 0959-9428 R&D Projects: GA ČR(CZ) GAP304/10/1951; GA AV ČR KAN200100801 Institutional research plan: CEZ:AV0Z10100520; CEZ:AV0Z40400503 Keywords : nanodiamond * luminiscence * DFT Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 5.968, year: 2011 http://pubs.rsc.org/en/content/articlelanding/2011/JM/C1JM13525B

  3. Military Nutrition Research: Four Tasks to Address Personnel Readiness and Warfighter Performance

    Science.gov (United States)

    2007-03-01

    hydrolyzed soy protein (98). Shelf and taste stability issues currently prevent the use of milk in combat rations. However, it would be advantageous to...Am J of Clin Nutr. 72(4):940-5, 2000 50 16. Loe YC, N Bergeron, N Rodriguez, and J-M Schwarz. A gas chromatography mass spectrometry method to...Schwarz J-M, Periasamy R, Park S, Tappy L. Effect of fructose overfeeding and fish oil administration on hepatic de novo lipogenesis and insulin

  4. Jane Austen and Addison's disease: an unconvincing diagnosis.

    Science.gov (United States)

    White, K G

    2009-12-01

    Jane Austen's letters describe a two-year deterioration into bed-ridden exhaustion, with unusual colouring, bilious attacks and rheumatic pains. In 1964, Zachary Cope postulated tubercular Addison's to explain her symptoms and her relatively pain-free illness. Literary scholars later countered this posthumous diagnosis on grounds that are not well substantiated, while medical authors supported his conclusion. Important symptoms reported by contemporary Addison's patients-mental confusion, generalised pain and suffering, weight loss and anorexia-are absent from Jane Austen's letters. Thus, by listening to the patient's perspective, we can conclude it is unlikely that Addison's disease caused Jane Austen's demise. Disseminated bovine tuberculosis would offer a coherent explanation for her symptoms, so that Cope's original suggestion of infective tuberculosis as the cause of her illness may have been correct.

  5. Changes of cell growth and magnetosome biomineralization in Magnetospirillum magneticum AMB-1 after ultraviolet-B irradiation

    Directory of Open Access Journals (Sweden)

    Yinzhao eWang

    2013-12-01

    Full Text Available Effects of ultraviolet radiation on microorganisms are of great interest in field of microbiology and planetary sciences. In the present study, we used Magnetospirillum magneticum AMB-1 as a model organism to examine the influence of ultraviolet-B (UV-B radiation on cell growth and magnetite biomineralization of magnetotactic bacteria. Live AMB-1 cells were exposed to UV-B radiation for 60 s, 300 s and 900 s, which correspond to radiation doses of 120 J/m2, 600 J/m2 and 1800 J/m2, respectively. After irradiation, the amounts of cyclobutane pyrimidine dimers and reactive oxygen species of the cells were increased, and cell growth was stunted up to ~170 h, depending on the UV-B radiation doses. The UV-B irradiated cells also produced on average more magnetite crystals with larger grain sizes and longer chains, which results in changes of their magnetic properties.

  6. Structural basis for clonal diversity of the human T-cell response to a dominant influenza virus epitope

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Xinbo; Chen, Guobing; Weng, Nan-ping; Mariuzza, Roy A. (NIH); (Maryland-BI)

    2017-09-20

    Influenza A virus (IAV) causes an acute infection in humans that is normally eliminated by CD8+ cytotoxic T lymphocytes. Individuals expressing the MHC class I molecule HLA-A2 produce cytotoxic T lymphocytes bearing T-cell receptors (TCRs) that recognize the immunodominant IAV epitope GILGFVFTL (GIL). Most GIL-specific TCRs utilize α/β chain pairs encoded by the TRAV27/TRBV19 gene combination to recognize this relatively featureless peptide epitope (canonical TCRs). However, ~40% of GIL-specific TCRs express a wide variety of other TRAV/TRBV combinations (non-canonical TCRs). To investigate the structural underpinnings of this remarkable diversity, we determined the crystal structure of a non-canonical GIL-specific TCR (F50) expressing the TRAV13-1/TRBV27 gene combination bound to GIL–HLA-A2 to 1.7 Å resolution. Comparison of the F50–GIL–HLA-A2 complex with the previously published complex formed by a canonical TCR (JM22) revealed that F50 and JM22 engage GIL–HLA-A2 in markedly different orientations. These orientations are distinguished by crossing angles of TCR to peptide–MHC of 29° for F50 versus 69° for JM22 and by a focus by F50 on the C terminus rather than the center of the MHC α1 helix for JM22. In addition, F50, unlike JM22, uses a tryptophan instead of an arginine to fill a critical notch between GIL and the HLA-A2 α2 helix. The F50–GIL–HLA-A2 complex shows that there are multiple structurally distinct solutions to recognizing an identical peptide–MHC ligand with sufficient affinity to elicit a broad anti-IAV response that protects against viral escape and T-cell clonal loss.

  7. A cytosolic juxtamembrane interface modulates plexin A3 oligomerization and signal transduction.

    Directory of Open Access Journals (Sweden)

    Rachael Barton

    Full Text Available Plexins (plxns are transmembrane (TM receptors involved in the guidance of vascular, lymphatic vessel, and neuron growth as well as cancer metastasis. Plxn signaling results in cytosolic GTPase-activating protein activity, and previous research implicates dimerization as important for activation of plxn signaling. Purified, soluble plxn extracellular and cytosolic domains exhibit only weak homomeric interactions, suggesting a role for the plxn TM and juxtamembrane regions in homooligomerization. In this study, we consider a heptad repeat in the Danio rerio PlxnA3 cytosolic juxtamembrane domain (JM for its ability to influence PlxnA3 homooligomerization in TM-domain containing constructs. Site-directed mutagenesis in conjunction with the AraTM assay and bioluminescent energy transfer (BRET² suggest an interface involving a JM heptad repeat, in particular residue M1281, regulates PlxnA3 homomeric interactions when examined in constructs containing an ectodomain, TM and JM domain. In the presence of a neuropilin-2a co-receptor and semaphorin 3F ligand, disruption to PlxnA3 homodimerization caused by an M1281F mutation is eliminated, suggesting destabilization of the PlxnA3 homodimer in the JM is not sufficient to disrupt co-receptor complex formation. In contrast, enhanced homodimerization of PlxnA3 caused by mutation M1281L remains even in the presence of ligand semaphorin 3F and co-receptor neuropilin-2a. Consistent with this pattern of PlxnA3 dimerization in the presence of ligand and co-receptor, destabilizing mutations to PlxnA3 homodimerization (M1281F are able to rescue motor patterning defects in sidetracked zebrafish embryos, whereas mutations that enhance PlxnA3 homodimerization (M1281L are not. Collectively, our results indicate the JM heptad repeat, in particular residue M1281, forms a switchable interface that modulates both PlxnA3 homomeric interactions and signal transduction.

  8. Comparison of various milling modes combined to the enzymatic hydrolysis of lignocellulosic biomass for bioenergy production: Glucose yield and energy efficiency

    International Nuclear Information System (INIS)

    Licari, A.; Monlau, F.; Solhy, A.; Buche, P.; Barakat, A.

    2016-01-01

    Bagasse is an abundant by-product from sugarcane production that can be used for conversion into biofuels. Nonetheless, the recalcitrant structures of lignocellulosic fibers required a pretreatment prior conversion into biofuels. In this study, four mechanical deconstruction methods were compared in terms of energy demand and energy efficiency at lab scale: BM (ball mill), VBM (vibratory ball mill), CM (centrifugal mill) and JM (jet mill). Results indicate that VBM was more effective compared to BM, JM and CM in enzymatic accessibility and sugars solubilization: VBM-3h > BM-72 h > JM-5000 rpm > CM-0.12 mm. However, preliminary energetic assessment showed that at lab scale, the CM (centrifugal mill) as mechanical fractionation process appears to be the most efficient in terms of energy-efficiency (kg glucose/kWh) compared to BM, VBM and JM. A comparison with literature pretreatments data highlighted that fine and/or ultrafine milling process (BM, VBM, CM) are simpler saccharification technologies, which not required any chemical or water inputs, thus minimizing waste generation and treatment. - Highlights: • VBM (vibro ball milling) was the most effective in decreasing of cellulose crystallinity. • BM (ball milling) was the most effective in increasing surface area. • The highest energy efficiency was obtained with CM (centrifugal milling).

  9. Fracture Toughness and Shear Strength of the Bonded Interface Between an Aluminium Alloy Skin and a FRP Patch

    Science.gov (United States)

    Kumar, Prashant; Shinde, Prakash Sonyabapu; Bhoyar, Gaurav

    2018-05-01

    The existing techniques to determine the fracture properties such as critical energy release rate in mode I (GIc) and mode II (GIIc) of an interface between two sheets of same material were modified to determine these properties between the sheets of dissimilar materials and thickness. In addition, the interface shear strength (ISS) was also determined. Experiments were carried out on the specimens made of a pre-cracked thin aluminium alloy skin and a Fiber reinforced polymer (FRP) patch. Two kinds of surface preparation of the aluminium skin were employed; (i) emery-paper roughened surface (ERS) and (ii) Sodium Hydroxide (NaOH) treated surface (NTS). GIc of ERS specimen was found to be 36.1 J/m2, while it was found to be much higher for NTS specimens, that is, 87.3 J/m2. GIIc was found to be 282.4 J/m2 for ERS specimens and much higher as 734.5 J/m2 for NTS specimens. ISS was determined as 32.6 MPa for ERS specimen and significantly higher for NTS specimen, that is, 44.5 MPa. The micrographs obtained from a field emission-scanning electron microscope (FE-SEM) and the surface roughness test showed that the NTS was significantly rougher than the ERS, explaining the higher values of all the three kinds of NTS specimens.

  10. Evaluation of BiliCare™ transcutaneous bilirubin device in Japanese newborns.

    Science.gov (United States)

    Yamana, Keiji; Morioka, Ichiro; Kurokawa, Daisuke; Fukushima, Sachiyo; Nishida, Kosuke; Ohyama, Shohei; Nishimura, Noriyuki; Nozu, Kandai; Taniguchi-Ikeda, Mariko; Nagase, Hiroaki; Fujioka, Kazumichi; Iwatani, Sota; Nakamura, Hajime; Iijima, Kazumoto

    2017-10-01

    Non-invasive transcutaneous bilirubin (TcB) monitoring has been widely used to screen for hyperbilirubinemia. TcB measured using the recently developed BiliCare™ system, however, has not been fully evaluated. One hundred and seven TcB measurements were obtained from 82 Japanese newborns ≥35 weeks' gestational age within 2 weeks after birth. Measurements were taken at the scaphoid fossa, conchal cavity, and lobe of the ear using BiliCare. BiliCare TcB were compared with total serum bilirubin (TB) and TcB obtained using another bilirubinometer (JM-105™). Transcutaneous bilirubin measured at all three sites significantly correlated with TB (r = 0.91, 0.93, and 0.93 at the scaphoid fossa, conchal cavity, and lobe, respectively). The mean differences were 0.1, -0.3, and 3.6 at the scaphoid fossa, conchal cavity, and lobe, respectively. BiliCare TcB at the scaphoid fossa significantly correlated with that using the JM-105 (r = 0.91). The mean difference was 0.0. BiliCare, however, produced a significantly higher and lower TcB than the JM-105 for TB bilirubin measurements taken at the scaphoid fossa or conchal cavity using BiliCare were more reliable than those at the earlobe. BiliCare TcB differed from those of the JM-105, for TB <7 or ≥15 mg/dL. © 2017 Japan Pediatric Society.

  11. Menadione 処理した Candida albicans ROS 生産機構の解析

    OpenAIRE

    上野, 将明; 小笠原, 綾子; 渡部, 俊彦; 三上, 健; 松本, 達二; ウエノ, ユキヒロ; オガサワラ, アヤコ; ワタナベ, トシユキ; ミカミ, タケシ; マツモト, タツジ; Yukihiro, UENO; Ayako, OGASAWARA; Toshihiko, WATANABE; Takeshi, MIKAMI; Tatsuji, MATSUMOTO

    2008-01-01

    Menadione shows anti Condida activity by promoting ROS production. However, the ROS production mechanism has not been clarifield. Thus, in this study, we studied thr relation between anti Candida activity of menadione and ROS production. Menadione inhibited the growth of C. albicans BWP17 strain, the growth of C. albicans JM02 strain was not inhibited. ROS production in C. albicans BWP17 strain was enhanced by addition of menadione. The ROS production in C. albicans JM02 strain was also enhan...

  12. Development and Testing of Physically-Based Methods for Filling Gaps in Remotely Sensed River Data: Annual Report Year 2

    Science.gov (United States)

    2012-09-30

    near Deerlodge Park to support a USGS surface-water modeling study. Similar modeling projects on the San Joaquin and Sheboygan River were aided over...September 5-7, 2012, San Jose, Costa Rica, 8p. Nelson, J.M., McDonald, R.R., Kinzel, P.J., and Legleiter, C.J., 2011, Using computational models to...of the International Conference on Fluvial Hydraulics, September 5-7, 2012, San Jose, Costa Rica, 8p. *Nelson, J.M., McDonald, R.R., Kinzel, P.J

  13. Hemorrhage Control for Major Traumatic Vascular Injuries

    Science.gov (United States)

    2017-10-01

    TJ, Eastridge BJ, Gilani R, Chung KK, DeSantis SM, DuBose JJ , Tomasek TS, Fortuna GR, Sames VG, Todd SR, Podbielski JM, Wade CE, Holcomb JB and the...Eastridge BJ, Gilani R, Chung KK, DeSantis SM, DuBose JJ , Tomasek JS, Fortuna GR, Sams VG, Todd SR, Podbielski JM, Wade CE, Holcomb JB. Multicenter...Kisat M, Morrison JJ , Hashmi ZG, Efron DT, Rasmussen TE, Haider AH. Epidemiology and outcomes of non-compressible torso hemorrhage. J Surg Res. 2013;184

  14. Numerical modeling of oil spill in the Patos Lagoon estuary; Modelagem numerica de derrames de oleo no estuario da Lagoa dos Patos

    Energy Technology Data Exchange (ETDEWEB)

    Martinho, Vivian; Monteiro, Igor Oliveira; Janeiro, Joao; Fernandes, Elisa Helena Leao [Fundacao Universidade do Rio Grande (FURG), RS (Brazil)

    2008-07-01

    Navigation is responsible for the input of 555.000 tons of oil per year in the marine environment. The recovery of the system can take dozens of years, affecting economical, ecological and social areas. The Patos Lagoon estuary presents wide importance and high susceptibility to accidents of oil spill. Therefore, the objective of this study is to analyze the spread of oil spills using the MOHID model, which simulates both the hydrodynamics of the estuary and the oil dispersion considering the different processes involved. Wind and water level data from May 1 to August 18, 1999 were used to simulate a hypothetic accident of involving 2000 m3 of oil MF 380 during the passage of a cold front considering high and low river discharges. Results indicate that the oil dispersion is governed by the estuarine dynamic, which is controlled by the wind action and river discharge. Thus, during southwest wind the oil is retained within the estuary, and in situations of northeast wind the oil tends to leave the estuary and sometimes can reach the inner shallow bays. (author)

  15. The effect of grain type and processing on chewing activity in horses

    DEFF Research Database (Denmark)

    Brøkner, Christine; Nørgaard, Peder; Eriksen, Lis

    2005-01-01

    The aims of the present experiment were to study the effect of grain type and processing on chewing activity in horses. Three adult trotters (Exp.I) and 3 adult Icelandic horses (Exp.II) were fed 3 daily meals during 3 consecutive days in two 3 x 3 completely randomized block design experiments....... Meals of (Exp.I: 1.0 kg) and (Exp.II: 0.5 kg) oats, barley and wheat were fed whole, rolled and ground at 10 am, 12 pm, 2 pm. Jaw movements (JM) were identified from pressure oscillations in a tube around the mouth. The efficient chewing time (EPTIME, min/kg DM), corrected for pauses, the basic chewing...... rate (PBCR, JM/s) and the standard deviation of time interval between JM (SPDDT), which indicate chewing regularity, were estimated. The mean EPTIME was 24 and 15 min for the Icelandic and trotter horses, respectively. The EPTIME for whole grain was 20 min and shorter than for ground grain (P = 0...

  16. RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements

    Directory of Open Access Journals (Sweden)

    Iván Plaza-Menacho

    2016-12-01

    Full Text Available Receptor tyrosine kinases exhibit a variety of activation mechanisms despite highly homologous catalytic domains. Such diversity arises through coupling of extracellular ligand-binding portions with highly variable intracellular sequences flanking the tyrosine kinase domain and specific patterns of autophosphorylation sites. Here, we show that the juxtamembrane (JM segment enhances RET catalytic domain activity through Y687. This phospho-site is also required by the JM region to rescue an otherwise catalytically deficient RET activation-loop mutant lacking tyrosines. Structure-function analyses identified interactions between the JM hinge, αC helix, and an unconventional activation-loop serine phosphorylation site that engages the HRD motif and promotes phospho-tyrosine conformational accessibility and regulatory spine assembly. We demonstrate that this phospho-S909 arises from an intrinsic RET dual-specificity kinase activity and show that an equivalent serine is required for RET signaling in Drosophila. Our findings reveal dual-specificity and allosteric components for the mechanism of RET activation and signaling with direct implications for drug discovery.

  17. Highlights from e-EPS: Jean-Michel Raimond wins EPS Edison-Volta Prize 2014

    CERN Multimedia

    Martina Knoop, e-EPS News

    2014-01-01

    e-EPS News is a monthly addition to the CERN Bulletin line-up, showcasing articles from e-EPS – the European Physical Society newsletter – as part of a collaboration between the two publications.   The European Physical Society has the pleasure to announce that the 2014 EPS Edison-Volta Prize is awarded to Jean-Michel Raimond for “seminal contribution to physics (that) have paved the way for novel explorations of quantum mechanics and have opened new routes in quantum information processing”. J.-M. Raimond’s PhD thesis was supervised by Serge Haroche at the École Normale Supérieure in Paris, France, in the early 1980′s, and together S. Haroche, M. Brune and J.-M. Raimond have built an extremely successful research group since then. J.-M. Raimond has made seminal contributions to the development of cavity QED experiments, in particular involving circular Rydberg atoms interacting with very high-Q superc...

  18. Application of foraminifers in ecotoxicology: Retrospect, perspect and prospect

    Digital Repository Service at National Institute of Oceanography (India)

    Nigam, R.; Saraswat, R.; Panchang, R.

    :112-123; 1964a. Bandy, O.; Ingle Jr., J.C.; Resig, J.M. Foraminifera, Los Angeles County outfall area, California. Limnol. Oceanogra. 9:124-137; 1964b. Bandy, O.; Ingle Jr., J.C.; Resig, J.M. Modification of foraminiferal trends, Hyperion Outfall, California.... Micropal. 10:109-113; 1991. Stott, L.D.; Hayden, T.P.; Griffith, J. Benthic foraminifera at the Los Angeles county Whites Point outfall revisited. J. Foram. Res. 26:357-368; 1996. Stouff, V.; Geslin, E.; Debenay, J.-P.; Lesourd, M. Origin...

  19. Pyrimidine dimer excision in human cells and skin cancer

    International Nuclear Information System (INIS)

    Regan, J.D.; Carrier, W.L.; Smith, D.P.; Waters, R.

    1977-01-01

    We have compared three different methods for estimating the induction and removal of uv induced pyrimidine dimers from the DNA of human fibroblasts. Results indicate that after uv doses of 5-20 J/m 2 50% of the dimers are removed by 24 hours after irradiation. Almost complete excision can be observed if the cells are incubated for periods not less than 72 hours after 5 J/m 2 . After higher doses it probably takes even longer fr such complete removal to be seen

  20. J.M. Keynes and His Economic Theory: an Ethical Perspective

    Directory of Open Access Journals (Sweden)

    Stanislav N. Ivaskovsky

    2016-01-01

    Full Text Available The article examines the philosophical and moral foundations of the biggest economist and political philosopher of the 20th century John Maynard Keynes (1883-1946, who played an important role in rethinking a number of important provisions of the classical political economy and in creating the ideological and methodological basis of the "Keynesian revolution" and of the new field of economic analysis-macroeconomics. The author traces the main stages in the formation of ethical views of Keynes, shows that his interest in ethics as the system of values in society was dictated by the need for the new conceptual vision of economic realities and by the search of an answer to the main ethical question: "What should we do?". Attention is drawn to the fact that an understanding of the ethical orientation of economic theory by Keynes allowed him to take a critical stance towards traditional individualism and Victorian morality of thrift and moneymaking and to conclude that rational and "right" forms of individual behaviour are not a guarantee of the prosperity of society as a whole. To achieve the latter Keynes justified the necessity of "central control" by the State of the overall level of aggregate expenditure. It isstressed that the ethical views of Keynes correspond with the concept of the "ethic of responsibility"- a relatively new scientific discipline, which originated as a response to the risks of technogenic era: pollution, resource constraints, overpopulation, lack of stability of the world economy. The final part of the article analyzes one of the most important, from the point of view of Keynes, vices of capitalism - reckless proclivity of people to the multiplication of "abstract monetary wealth". It is shown that it doesn't only disfigure the psyche and consciousness of people, but also changes the direction of development of the market economy towards "speculative capitalism", which creates a threat to civilization, creativity, well-being and full development of the individual.

  1. THE PARADOx OF BEING A WOUNDED HEALER: HENRI J.M. ...

    African Journals Online (AJOL)

    2010-08-19

    Aug 19, 2010 ... e o lo g ic a l S tu d ie s http://www.hts.org.za. HTS. Original .... pastors have to deal with, the relativisation of biblical and religious ..... that we are led into the truth and life (John 14:6). This .... Collins & Sellina [1999] 2001:63); in terms of spirituality, God ..... Hadot, P., 2002, What is ancient philosophy?, transl.

  2. J.M. Coetzee: 'n Geskryfde Lewe. J. C. Kannemeyer. Johannesburg ...

    African Journals Online (AJOL)

    'n paar maal. Hoewel hy 'n deeglike bespre- king van die afwesigheid van die outeur in. Coetzee se outobiografiese trilogie lewer, maak Kannemeyer soms op onaanvaarbare wyse gebruik van die tekste as bronne. So byvoorbeeld is die beskrywing van Outa Jaap. (50, 51) byna direk vertaal uit Boyhood (84 in die Secker ...

  3. “General Theory” of J.M. Keynes: 80 Years After

    Directory of Open Access Journals (Sweden)

    Anatoly V. Kholopov

    2016-01-01

    Full Text Available The Keynes' "General Theory", published 80 years ago, overthrew the neoclassical orthodoxy and created a new understanding of how market economy works. The main idea of the "General Theory" is that the amount of employment depends on the level of effective demand. Keynes believed that much economic activity is governed by "animal spirits" because of the existence of inescapable uncertainty about the future. In Keynes' view these "animal spirits" are the main cause for economic fluctuations. The uncertainty and "animalspirits"make investments unstable. He made distinction between risk (which is measurable and uncertainty (which is not. This is the reason why Keynes opposed the excessive mathematicization of economics. His another important impact on economics was to switch the focus of economic analysis from the long run to the short term. The message of "General Theory" was that government should manage demand to limit economic fluctuations. The role Keynes gave the state was essentially to reduce uncertainty and to make economy more predictable.

  4. An Exploratory Survey of Methods Used to Develop Measures of Performance

    Science.gov (United States)

    1993-09-01

    E3 Genichi Taguchi O3 Robert C. Camp 0 Kaoru Ishikawa 0 Dorsey J. Talley o Philip B. Crosby 0 J.M. Juran 0 Arthur R. Tenner 0 W. Edwards Deming 0...authored books or papers on the subject of quality? (Mark all that apply) o Nancy Brady 0 H. James Harrington 03 Genichi Taguchi o Robert C. Camp 0 Kaoru ... Ishikawa 03 Dorsey J. Talley 0 Philip B. Crosby 0 J.M. Juran 0 Arthur R. Tenner o W. Edwards Deming 0 Dennis Kinlaw 03 Hans J. Thamhain 0 Irving J

  5. Physics and Applications of Defects in Advanced Semiconductors. Materials Research Society Symposium Proceedings. Volume 325

    Science.gov (United States)

    1994-01-01

    incorporation during growth rather than self-compensation. Chin et al.9 have achieved hole concentrations as high as 3x10 19 cmn3 for x - 0.5 using CC14...Chemical Beams Epitaxy, Oxford, UK, Sept. 1991, paper 02. 9. T.P. Chin , PD. Kirchner, J.M. Woodall, and C.W. To, App!. Phya LAtt. 59,2865 (1991). 10...Patrick Chye , Phys. Rev. Let., 44,420 (1980) 16. J.C. Bourgion, D. Stievenard, D. Deresme& and J.M. Arroyo, J. Appl. Phys., 69,284 (1991) 17. F

  6. An Operational Coastal Forecasting System in Galicia (NW Spain)

    Science.gov (United States)

    Balseiro, C. F.; Carracedo, P.; Pérez, E.; Pérez, V.; Taboada, J.; Venacio, A.; Vilasa, L.

    2009-09-01

    The Galician coast (NW Iberian Peninsula coast) and mainly the Rias Baixas (southern Galician rias) are one of the most productive ecosystems in the world, supporting a very active fishing and aquiculture industry. This high productivity lives together with a high human pressure and an intense maritime traffic, which means an important environmental risk. Besides that, Harmful Algae Blooms (HAB) are common in this area, producing important economical losses in aquiculture. In this context, the development of an Operational Hydrodynamic Ocean Forecast System is the first step to the development of a more sophisticated Ocean Integrated Decision Support Tool. A regional oceanographic forecasting system in the Galician Coast has been developed by MeteoGalicia (the Galician regional meteorological agency) inside ESEOO project to provide forecasts on currents, sea level, water temperature and salinity. This system is based on hydrodynamic model MOHID, forced with the operational meteorological model WRF, supported daily at MeteoGalicia . Two grid meshes are running nested at different scales, one of ~2km at the shelf scale and the other one with a resolution of 500 m at the rias scale. ESEOAT (Puertos del Estado) model provide salinity and temperature fields which are relaxed at all depth along the open boundary of the regional model (~6km). Temperature and salinity initial fields are also obtained from this application. Freshwater input from main rivers are included as forcing in MOHID model. Monthly mean discharge data from gauge station have been provided by Aguas de Galicia. Nowadays a coupling between an hydrological model (SWAT) and the hydrodynamic one are in development with the aim to verify the impact of the rivers discharges. The system runs operationally daily, providing two days of forecast. First model verifications had been performed against Puertos del Estado buoys and Xunta de Galicia buoys network along the Galician coast. High resolution model results

  7. Effects of waves on water dispersion in a semi-enclosed estuarine bay

    Science.gov (United States)

    Delpey, M. T.; Ardhuin, F.; Otheguy, P.

    2012-04-01

    The bay of Saint Jean de Luz - Ciboure is a touristic destination located in the south west of France on the Basque coast. This small bay is 1.5km wide for 1km long. It is semi-enclosed by breakwaters, so that the area is mostly protected from waves except in its eastern part, where wave breaking is regularly observed over a shallow rock shelf. In the rest of the area the currents are generally weak. The bay receives fresh water inflows from two rivers. During intense raining events, the rivers can introduce pollutants in the bay. The input of pollutants combined with the low level dynamic of the area can affect the water quality for several days. To study such a phenomenon, mechanisms of water dispersion in the bay are investigated. The present paper focuses on the effects of waves on bay dynamics. Several field experiments were conducted in the area, combining wave and current measurements from a set of ADCP and ADV, lagrangian difter experiments in the surfzone, salinity and temperature profile measurements. An analysis of this set of various data is provided. It reveals that the bay combines remarkable density stratification due to fresh water inflows and occasionally intense wave-induced currents in the surfzone. These currents have a strong influence on river plume dynamics when the sea state is energetic. Moreover, modifications of hydrodynamics in the bay passes are found to be remarkably correlated with sea state evolutions. This result suggests a significant impact of waves on the bay flushing. To further analyse these phenomena, a three dimensional numerical model of bay hydrodynamics is developed. The model aims at reproducing fresh water inflows combined with wind-, tide- and wave-induced currents and mixing. The model of the bay is implemented using the code MOHID , which has been modified to allow the three dimensional representation of wave-current interactions proposed by Ardhuin et al. [2008b] . The circulation is forced by the wave field modelled

  8. Study of heat and salt transport processes in the Espinheiro Channel (Ria de Aveiro)

    Science.gov (United States)

    Vaz, Nuno Alexandre Firmino

    O principal objectivo deste trabalho consistiu no estudo da dinâmica termohalina do Canal do Espinheiro em funcao de dois forcamentos principais: mare e caudal fluvial, usando duas abordagens distintas: trabalho experimental e modelacao numerica. A propagacao da mare e o caudal fluvial do Rio Vouga sao determinantes no estabelecimento da estrutura horizontal da salinidade ao longo do canal. A estrutura termica horizontal ao longo do canal e, em grande parte, determinada pela variacao sazonal da temperatura da agua do Rio Vouga, bem como, pela variacao sazonal das condicoes meteorologicas devido a reduzida profundidade. Foi observada a formacao de fortes gradientes de salinidade (relacionados com a formacao de frentes estuarinas) numa regiao a cerca de 7-8 km da embocadura do canal, observando-se a sua migracao numa regiao de aproximadamente 1 km, dependendo do regime de mare. O balanco entre o transporte de sal de natureza advectiva e difusiva foi calculado, revelando que junto a embocadura os processos fisicos que mais contribuem para o transporte de sal sao a circulacao residual e o aprisionamento da agua em canais secundarios. Junto a foz do Rio Vouga os termos devidos a descarga fluvial e a circulacao gravitacional dominam o transporte de sal. Foi calibrado e validado um modelo numerico (Mohid, em modo 2D e 3D), sendo posteriormente utilizado para estudar a hidrologia do canal. Foi concedida particular atencao ao estudo da hidrologia em condicoes extremas de caudal fluvial e de mare. Os resultados da modelacao numerica permitiram numa primeira fase avaliar o bom desempenho do Mohid na reproducao dos escoamentos barotropicos na Ria de Aveiro, bem como na evolucao temporal das propriedades termohalinas da agua. Sob condicoes de caudal fluvial reduzido, a dinâmica do canal e essencialmente dominada pela mare. Com o aumento do caudal fluvial, a influencia da agua doce estende-se para jusante, estratificando a coluna de agua. As simulacoes 3D do Canal do

  9. Atomistic simulation of femtosecond laser pulse interactions with a copper film: Effect of dependency of penetration depth and reflectivity on electron temperature

    Science.gov (United States)

    Amouye Foumani, A.; Niknam, A. R.

    2018-01-01

    The response of copper films to irradiation with laser pulses of fluences in the range of 100-6000 J/m2 is simulated by using a modified combination of a two-temperature model (TTM) and molecular dynamics (MD). In this model, the dependency of the pulse penetration depth and the reflectivity of the target on electron temperature are taken into account. Also, the temperature-dependent electron-phonon coupling factor, electron thermal conductivity, and electron heat capacity are used in the simulations. Based on this model, the dependence of the integral reflectivity on pulse fluence, the changes in the film thickness, and the evolution of density and electron and lattice temperatures are obtained. Moreover, snapshots that show the melting and disintegration processes are presented. The disintegration starts at a fluence of 4200 J/m2, which corresponds with an absorbed fluence of 616 J/m2. The calculated values of integral reflectivity are in good agreement with the experimental data. The inclusion of such temperature-dependent absorption models in the TTM-MD method would facilitate the comparison of experimental data with simulation results.

  10. Increased susceptibility to in vitro ultraviolet B radiation in fibroblasts and lymphocytes cultured from systemic lupus erythematosus patients

    International Nuclear Information System (INIS)

    Golan, T.D.; Foltyn, V.; Roueff, A.

    1991-01-01

    Sunlight is known to induce exacerbations of systemic lupus erythematosus (SLE) but its mechanism remains unclear. We have previously reported that ultraviolet A (UVA) exposure induces an increase in total DNA synthesis (DS) in vitro but a decrease in unscheduled DNA repair synthesis (UDRS) of splenocytes of murine SLE strains. In order to investigate whether similar observations are characteristic of human SLE, peripheral blood lymphocytes (PBL) and dermal fibroblast (DF) cultures of 20 patients and 15 matched controls were exposed in vitro to UVA or UVB at different doses. Thirteen (65%) SLE DF cultures exposed to UVB light (12-24 J/m2) showed an increase in DS compared to paired unirradiated cultures. In contrast, UVB-irradiated DF from normal individuals had no significant increase in DS following UVB irradiation. When SLE DF were exposed to higher doses of UVB (48-96 J/m2), 90% of cultures showed a decrease in DS compared to only 20% in the control group. All of the SLE DF cultures showed a decrease of their unscheduled DNA repair capacity following UVB (24-48 J/m2) irradiation whereas no UDRS was apparent in 74% of controls under the same conditions. Similar findings regarding UDRS were observed in SLE PBL cultures and were also confirmed by autoradiography. UVA exposure (0-3840 J/m2) had no effect on DS nor on UDRS in DF or PBL cultured from SLE and controls. The relevance of these in vitro findings to the in vivo pathogenesis of the disease is discussed

  11. Mode I type delamination fracture toughness of YBCO coated conductor with additional Cu layer

    International Nuclear Information System (INIS)

    Miyazato, T.; Hojo, M.; Sugano, M.; Adachi, T.; Inoue, Y.; Shikimachi, K.; Hirano, N.; Nagaya, S.

    2011-01-01

    A fracture toughness test method was developed for a YBCO coated conductor with an additional Cu layer. Mode I type tests were carried out using double cantilever beam (DCB) specimens. Delamination propagated into the YBCO layer, and sometimes reached the Ag/YBCO interface. The fracture toughness for YBCO was about 10 J/m 2 . That for Ag/YBCO interface was about 100 J/m 2 . Although interlaminar fracture at a YBa 2 Cu 3 O 7-δ (YBCO)/CeO 2 interface was reported for YBCO coated conductors, this has not yet been investigated by a fracture mechanical approach. In the present study, we developed a mode I type fracture toughness test method for a YBCO coated conductor with an additional Cu layer using double cantilever beam (DCB) specimens. Fracture mechanism was investigated by microscopic observation by a scanning electron microscope (SEM), together with composition analysis by an energy dispersive X-ray spectroscope (EDS). A pre-crack introduced at the YBCO/CeO 2 interface deviated from the interface, and propagated into the YBCO layer, and sometimes reached the Ag/YBCO interface. The fracture toughness, G R , for YBCO and the Ag/YBCO interface was evaluated to be 7-10 J/m 2 and 80-120 J/m 2 , respectively. The complex stress intensity factor ratio, K 2 /K 1 , at YBCO/CeO 2 interface was evaluated to be -0.19, and this ratio controlled the formation of microcracks in the YBCO layer. The main crack propagated into the YBCO layer accompanied with the formation of microcracks.

  12. Ultraviolet light immunomodulation of canine islets for prolongation of allograft survival

    International Nuclear Information System (INIS)

    Kenyon, N.S.; Strasser, S.; Alejandro, R.

    1990-01-01

    Ultraviolet (UV) light treatment of donor islets has been shown to be effective for the prolongation of islet allograft survival in rodent models. This study evaluated UV as an immunomodulator of canine islets. The effects of UV irradiation on islet secretory function in vitro revealed a trend of increasing basal insulin release with increasing doses of UV and a corresponding significant decrease in glucose-mediated insulin release (expressed as percentage of basal fractional insulin release) beginning at UV light exposures of 200-300 J/m2 (n = 3, P less than 0.05). Proliferative responses to UV-irradiated allogeneic peripheral blood leukocytes and islets were significantly decreased by 53-112% (P less than 0.05) in 27 of 29 mixed-lymphocyte cultures and by 35-74% (P less than 0.05) in 4 of 5 mixed-lymphocyte islet culture experiments, respectively, beginning at 200-600 J/m2. Autotransplantation of nonirradiated (n = 8) and irradiated islets (600 J/m2, n = 6) resulted in a 1-mo graft survival rate of 75% for the control group and 50% for the irradiated group. Allotransplantation of irradiated islets (600 J/m2) into either nonimmunosuppressed recipients (1 donor to 1 recipient, n = 8) or recipients of subimmunosuppressive doses of cyclosporin (2 donors to 1 recipient, n = 4) resulted in 100% rejection by day 10. In contrast, when islets were cultured for 24 h postirradiation and transplanted into cyclosporin-treated pancreatectomized recipients (2 donors to 1 recipient), 3 of 7 grafts were prolonged beyond day 10 to days 16, 26, and greater than 100

  13. Comparison of UVB and UVC irradiation disinfection efficacies on Pseudomonas Aeruginosa (P. aeruginosa) biofilm

    Science.gov (United States)

    Argyraki, A.; Markvart, M.; Nielsen, Anne; Bjarnsholt, T.; Bjørndal, L.; Petersen, P. M.

    2016-04-01

    Disinfection routines are important in all clinical applications. The uprising problem of antibiotic resistance has driven major research efforts towards alternative disinfection approaches, involving light-based solutions. Pseudomonas aeruginosa (P. aeruginosa) is a common bacterium that can cause skin, soft tissue, lungs, kidney and urinary tract infections. Moreover, it can be found on and in medical equipment causing often cross infections in hospitals. The objective of this study was to test the efficiency, of two different light-based disinfection treatments, namely UVB and UVC irradiation, on P. aeruginosa biofilms at different growth stages. In our experiments a new type of UV light emitting diodes (LEDs) were used to deliver UV irradiation on the biofilms, in the UVB (296nm) and UVC (266nm) region. The killing rate was studied as a function of dose for 24h grown biofilms. The dose was ramped from 72J/m2 to 10000J/m2. It was shown that UVB irradiation was more effective than UVC irradiation in inactivating P. aeruginosa biofilms. No colony forming units (CFU) were observed for the UVB treated biofilms when the dose was 10000 J/m2 (CFU in control sample: 7.5 x 104). UVB irradiation at a dose of 20000J/m2 on mature biofilms (72h grown) resulted in a 3.9 log killing efficacy. The fact that the wavelength of 296nm exists in daylight and has such disinfection ability on biofilms gives new perspectives for applications within disinfection at hospitals.

  14. Three-dimensional flow and turbulence structure in electrostatic precipitator

    DEFF Research Database (Denmark)

    Ullum, Thorvald Uhrskov; Larsen, Poul Scheel; Özcan, Oktay

    2002-01-01

    Stereo PIV is employed to study the three-dimensional velocity and turbulence fields in a laboratory model of a negative corona, barbed-wire, smooth-plate, electrostatic precipitator (figure 1). The study is focused on determining the parametric effects of axial development, mean current density Jm...... and bulk velocity U0 on secondary flows and turbulence levels and structures due to the action of the three-dimensional electrostatic field on the charged gas. At constant bulk velocity (U0 = 1 m/s) and current density (Jm = 0.4 mA/m2), secondary flows in the form of rolls of axial vorticity with swirl...

  15. A comparison of different quasi-newton acceleration methods for partitioned multi-physics codes

    CSIR Research Space (South Africa)

    Haelterman, R

    2018-02-01

    Full Text Available & structures, 88/7, pp. 446–457 (2010) 8. J.E. Dennis, J.J. More´, Quasi-Newton methods: motivation and theory. SIAM Rev. 19, pp. 46–89 (1977) A Comparison of Quasi-Newton Acceleration Methods 15 9. J.E. Dennis, R.B. Schnabel, Least Change Secant Updates... Dois Metodos de Broyden. Mat. Apl. Comput. 1/2, pp. 135– 143 (1982) 25. J.M. Martinez, A quasi-Newton method with modification of one column per iteration. Com- puting 33, pp. 353–362 (1984) 26. J.M. Martinez, M.C. Zambaldi, An Inverse Column...

  16. Quasi-Newton methods for the acceleration of multi-physics codes

    CSIR Research Space (South Africa)

    Haelterman, R

    2017-08-01

    Full Text Available .E. Dennis, J.J. More´, Quasi-Newton methods: motivation and theory. SIAM Rev. 19, pp. 46–89 (1977) [11] J.E. Dennis, R.B. Schnabel, Least Change Secant Updates for quasi- Newton methods. SIAM Rev. 21, pp. 443–459 (1979) [12] G. Dhondt, CalculiX CrunchiX USER...) [25] J.M. Martinez, M.C. Zambaldi, An Inverse Column-Updating Method for solving large-scale nonlinear systems of equations. Optim. Methods Softw. 1, pp. 129–140 (1992) [26] J.M. Martinez, On the convergence of the column-updating method. Comp. Appl...

  17. Kinetic and dose dependencies of the SOS-induction in E.coli K-12 (uvrA) cells exposed to different UV doses

    International Nuclear Information System (INIS)

    Komova, O.V.; Kandiano, E.S.; Malavina, G.; )

    2000-01-01

    Kinetic and dose dependencies of the SOS-induction in E. coli (uvrA) cells exposed to UV light were investigated. below 2 J/m 2 the rate of the SOS-induction increased with dose. Maximal level of the SOS-response was proportional to the UV dose. Pyrimidine dimers were necessary for the induction. In the dose range 2-10 J/m 2 the rate of SOS-induction decreased with dose. Dose-maximum response curve was non-linear. Pyrimidine dimers were not required for the induction. nature of the molecular events leading to the SOS-induction at low and high doses was discussed [ru

  18. Technology-enhanced learning should be employed alongside – not instead of – bedside teaching

    Directory of Open Access Journals (Sweden)

    Ferguson Z

    2016-02-01

    Full Text Available Zachary FergusonSouth Thames Foundation School, London, UKI read with great interest the editorial by Al-jibury et al1 regarding the digitalization of medical education, particularly as I was part of the team that produced the YouTube video on heart murmurs which they reference in their paper.I agree wholeheartedly that digital resources cannot and must not replace bedside teaching. The video in question carries a disclaimer at the beginning, encouraging learners to use the resource as a companion to – not a substitute for – real-life patient contact. Convenient though YouTube might be, it cannot compare to the learning experience Al-jibury et al1 describes: listening to a live, beating heart. Bedside teaching has been around since the days of Hippocrates and it is not going anywhere anytime soon.Read the original article by Al-jibury et al.

  19. JM Maweu The Morality of Profit in Business pp75-89

    African Journals Online (AJOL)

    JM Maweu

    The main argument of this theoretical paper is that the pursuit of honest profits ... Is the pursuit of profits in business compatible with ethical business behavior? ..... behavior since the doctrine of maximizing self interest rooted in ethical egoism.

  20. Narrative authority in J.M. Coetzee's Age of Iron | Duncan | Tydskrif ...

    African Journals Online (AJOL)

    Tydskrif vir letterkunde. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 43, No 2 (2006) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here ...

  1. Opera, Byron, and a South African Psyche in JM Coetzee's Disgrace

    African Journals Online (AJOL)

    At the close of Coetzee's novel Disgrace, Professor David Lurie retreats into a state of alienation. He chooses both a physical and psychic reality removed from a functioning democratic South Africa. In this state he attempts to compose an opera on Lord Byron and Teresa Guiccioli, which becomes representative on many ...

  2. J.M. Coetzee's aesthetics of Ahimsa : towards a Gandhian reading of ...

    African Journals Online (AJOL)

    The topical subject of vegetarianism and non-violence towards animals is gaining currency in literary circles, as is attested by the award of the Man Booker International Prize to Han Kang's The Vegetarian in 2016. There has been a rash of talks and conferences which explore the idea of veganism/vegetarianism and its ...

  3. Survival and DNA repair in ultraviolet-irradiated haploid and diploid cultured frog cells

    International Nuclear Information System (INIS)

    Freed, J.J.; Hoess, R.H.; Angelosanto, F.A.; Massey, H.C. Jr.

    1979-01-01

    Survival and repair of DNA following ultraviolet (254-nm) radiation have been investigated in ICR 2A, a cultured cell line from haploid embryos of the grassfrog, Rana pipiens. Survival curves from cells recovering in the dark gave mean lethal dose value (D 0 ) in the range 1.5-1.7 Jm -2 for both haploid and diploid cell stocks. The only significant difference observed between haploids and diploids was in the extent of the shoulder at low fluence (Dsub(q)), the value for exponentially multiplying diploid cells (3.0 Jm -2 ) being higher than that found for haploids (1.2 Jm -2 ). Irradiation of cultures reversibly blocked in the G1 phase of the cell cycle gave survival-curve coefficients indistinguishable between haploids and diploids. Post-irradiation exposure to visible light restored colony-forming capacity and removed chromatographically estimated pyrimidine dimers from DNA at the same rates. After fluences killing 90% of the cells, complete restoration of survival was obtained after 60-min exposure to 500 foot-candles, indicating that in this range lethality is entirely photoreversible and therefore attributable to pyrimidine dimers in DNA. Dimer removal required illumination following ultraviolet exposure, intact cells and physiological temperature, implying that the photoreversal involved DNA photolyase activity. Excision-repair capacity was slight, since no loss of dimers could be detected chromoatographically during up to 48 h incubation in the dark and since autoradiographically detected 'unscheduled DNA synthesis' was limited to a 2-fold increase saturated at 10 Jm -2 . These properties make ICR 2A frog cells useful to explore how DNA-repair pathways influence mutant yield. (Auth.)

  4. Perubahan Lingkungan Mikro pada Berbagai Penutupan Lahan Hasil Revegetasi (Micro Environmental Change in Various Form Land Cover Revegetation

    Directory of Open Access Journals (Sweden)

    Dadan Mulyana

    2011-07-01

    Full Text Available Evaluation of land rehabilitation (revegetation activities is necessary for measuring the extent of success of the ongoing activities in rehabilitating and recovering degraded lands. One way for evaluating the success of land rehabilitation (revegetation is by determining the changes of micro enviroment.  The objective of this research was to study the changes of micro environment in  various types of revegetated land cover, including scrub/bush land (SB, agricultural land (TP, monoculture teak (JM and mixed crops (TC in Ciliwung upper watershed. Research results showed that the highest air temperature and soil temperature were  obtained at SB, respectively at 32.8 0C and 26.5 0C, and the lowest at TC, respectively at 28.1 0C and 20.7 0C. Relative humidity and soil moisture were highest at TC (72.3% and 96% and lowest at SB (60.8%, and the lowest soil moisture occurred at JM (45%.  The highest infiltration rate occurred on TP (475.5 mm h-1, very rapid, followed by JM (117 mmh-1, fast and TC (80 mm h-1, and the lowest at SB (17.65 mm h-1, medium slow.  Erosion reductions occurred after 6 years of the revegetation activities with the following  results:TC  (96,676.1 ton year-1 ha-1, JM (10,790 ton year-1 ha-1, TP and SB (52,867.9 ton year-1 ha-1 and 24,612.6 ton year-1 ha-1.  The micro environments for all land cover types were better after revegetation activities.Keywords: micro environment, land cover, erosion, infiltration, upper watershed

  5. Hydrodynamic cavitation to improve bulk fluid to surface mass transfer in a nonimmersed ultraviolet system for minimal processing of opaque and transparent fluid foods.

    Science.gov (United States)

    Milly, P J; Toledo, R T; Chen, J; Kazem, B

    2007-11-01

    Ultraviolet (UV)-induced chemical reactions and inactivation of microorganisms in transparent and opaque fluids are strongly dependent upon the homogenous exposure of the target species to the UV irradiation. Current UV technologies used in water disinfection and food preservation applications have limited efficacy due to suspended particles shading target species. An Ultraviolet-Shockwave Power Reactor (UV-SPR) consisting of an inner rotating rotor and a stationary quartz housing and 2 end plates was used to induce 'controlled cavitation.' Eight UV low-pressure mercury lamps spaced uniformly were installed lengthwise around the quartz housing periphery. A KI to I(3) (-)chemical dosimeter for UV was used to quantify photons received by fluid in the annular space of the SPR. UV dose (J/m(2)) increased from 97 J/m(2) at 0 rpm to over 700 J/m(2) for SPR speeds above 2400 rpm. Inactivation of E. coli 25922 in apple juice and skim milk in the UV-SPR at exit temperatures below 45 degrees C was greater than 4.5 and 3 logs, respectively. The UV-SPR system proved successful in increasing the mass transfer of transparent and opaque fluid to the UV irradiated surface.

  6. Kinetic and dose dependences of the SOS-induction in E.coli K-12 (uvrA) cells exposed to the different UV doses

    International Nuclear Information System (INIS)

    Komova, O.V.; Kandiano, E.S.; Malavya, G.

    1999-01-01

    The kinetic and dose dependences of the SOS-induction in E.coli (uvrA) cells exposed to UV light were investigated. Below 2 J/m 2 the rate of the SOS-induction increased with dose. The maximal level of the SOS-response was proportional to the UV dose. Pyrimidine dimers were necessary for the induction. In the dose range 2-10 J/m 2 the rate of the SOS-induction decreased with dose. The dose-response curve was non-linear. Pyrimidine dimers were not required for the induction. The nature of the molecular events leading to the SOS-induction at low and high UV doses was discussed. (author)

  7. Economic Drivers of Strategic & Critical Materials

    Science.gov (United States)

    2012-05-01

    Calla<la. r>eru, cnre ZINC 7J ----i Can.ad:J, Peru, Mexico, l relaniJ TIT .. .Nll.JM (&p1111ge) ’i">9 -----j K azaUI&tan. Japan. ~ R~a ~.0:!\\JM Ml N...G YPS’Uloil PHOSPI1AT E ROCK IRON and STEEL IRON and STE EL SlAG OEME:NT PUMICE DIIL\\IO.N !> (na:lr.ll t1du&trtal s!Oile) U:ME STO.N E (Ct...PLATINUM ZINC TU.NGSTE.N mA.~w.l ($f10nge) HICK EL PEAT MAGNESIUM METAL SltVER S t’UCON BERYLUUM MAGNESIUM COMPOU l>S ALUMI NUM PUMICIE

  8. Using Numerical Models in the Development of Software Tools for Risk Management of Accidents with Oil and Inert Spills

    Science.gov (United States)

    Fernandes, R.; Leitão, P. C.; Braunschweig, F.; Lourenço, F.; Galvão, P.; Neves, R.

    2012-04-01

    substances, helping in the management of the crisis, in the distribution of response resources, or prioritizing specific areas. They can also be used for detection of pollution sources. However, the resources involved, and the scientific and technological levels needed in the manipulation of numerical models, had both limited the interoperability between operational models, monitoring tools and decision-support software tools. The increasing predictive capacity of metocean conditions and fate and behaviour of pollutants spilt at sea or costal zones, and the presence of monitoring tools like vessel traffic control systems, can both provide a safer support for decision-making in emergency or planning issues associated to pollution risk management, especially if used in an integrated way. Following this approach, and taking advantage of an integrated framework developed in ARCOPOL (www.arcopol.eu) and EASYCO (www.project-easy.info) projects, three innovative model-supported software tools were developed and applied in the Atlantic Area, and / or the Portuguese Coast. Two of these tools are used for spill model simulations - a web-based interface (EASYCO web bidirectional tool) and an advanced desktop application (MOHID Desktop Spill Simulator) - both of them allowing end user to have control over the model simulations. Parameters such as date and time of the event, location and oil spill volume are provided the users; these interactive tools also integrate best available metocean forecasts (waves, meteorological, hydrodynamics) from different institutions in the Atlantic Area. Metocean data are continuously gathered from remote THREDDS data servers (using OPENDAP) or ftp sites, and then automatically interpolated and pre-processed to be available for the simulators. These simulation tools developed can also import initial data and export results from/to remote servers, using OGC WFS services. Simulations are provided to end user in a matter of seconds, and thus, can be very

  9. "Children are faced with two alternatives, either to watch TV in English or to watch Russian TV"

    Index Scriptorium Estoniae

    2006-01-01

    Vajadusest muuta Leedu televisiooni seadust, et Leedu emigrandid saaksid ka Iirimaal jm vaadata kodumaiseid televisiooniprogramme. Kommenteerib Leedu Raadio ja Televisiooni direktor Kestutis Petrauskis

  10. Uue tehnoloogiaga varustatud William Morrise poeg = The son of William Morris - equipped with new technology / Peter Davey ; interv. Georg Poslawski

    Index Scriptorium Estoniae

    Davey, Peter

    2000-01-01

    Inglise arhitekt ja arhitektuuriajaloolane Peter Davey arhitektuurikriitika traditsioonidest ja rollist, identiteedist ja kopeerimisest arhitektuuris, arhitektuuriajakirjade mõjust ühiskondlikule elule, soome arhitektuurist jm

  11. Tiskresse rajatakse Aaviku elamurajoon / Tiit Nurklik ; interv. Harri Treial

    Index Scriptorium Estoniae

    Nurklik, Tiit

    2001-01-01

    Elamurajooni ehitama hakkava KMG Ehitus AS-i direktor M. Nurklik elamurajooni planeeringust, elamute arhitektuurist, hoonevariantidest, ruumijaotusest, konstruktsioonidest, väliskattest jm. Arhitekt Emil Urbel

  12. Media Non Grata : Pärnu fideo- ja vilmifestival / Raivo Kelomees

    Index Scriptorium Estoniae

    Kelomees, Raivo, 1960-

    1999-01-01

    Eksponeeritud olid video, film, dokumentaalid, animatsioonid jm. Peakorraldaja Academia Non Grata, Al Paldrok ja tema sõbrad-kolleegid. Sütevaka Andrese performance'ist. Programmidest, valupunktidest

  13. Cognitive systems engineering in health care

    CERN Document Server

    Bisantz, Ann M; Fairbanks, Rollin J

    2014-01-01

    Cognitive Engineering for Better Health Care Systems, Ann M. Bisantz, Rollin J. Fairbanks, and Catherine M. BurnsThe Role of Cognitive Engineering in Improving Clinical Decision Support, Anne Miller and Laura MilitelloTeam Cognitive Work Analysis as an Approach for Understanding Teamwork in Health Care, Catherine M. BurnsCognitive Engineering Design of an Emergency Department Information System, Theresa K. Guarrera, Nicolette M. McGeorge, Lindsey N. Clark, David T. LaVergne, Zachary A. Hettinger, Rollin J. Fairbanks, and Ann M. BisantzDisplays for Health Care Teams: A Conceptual Framework and Design Methodology, Avi ParushInformation Modeling for Cognitive Work in a Health Care System, Priyadarshini R. PennathurSupport for ICU Clinician Cognitive Work through CSE, Christopher Nemeth, Shilo Anders, Jeffrey Brown, Anna Grome, Beth Crandall, and Jeremy PamplinMatching Cognitive Aids and the "Real Work" of Health Care in Support of Surgical Microsystem Teamwork, Sarah Henrickson Parker and Shawna J. PerryEngageme...

  14. Amine functionalized graphene oxide/CNT nanocomposite for ultrasensitive electrochemical detection of trinitrotoluene

    Energy Technology Data Exchange (ETDEWEB)

    Sablok, Kavita; Bhalla, Vijayender; Sharma, Priyanka; Kaushal, Roohi; Chaudhary, Shilpa [Institute of Microbial Technology (CSIR) Sector-39A, Chandigarh160036 (India); Suri, C. Raman, E-mail: raman@imtech.res.in [Institute of Microbial Technology (CSIR) Sector-39A, Chandigarh160036 (India)

    2013-03-15

    Highlights: ► Binding of electron-deficient trinitrotoluene to the electron rich amino groups to form JM complexes. ► rGO/CNT based platform for enhanced electrochemical detection. ► Functionalization and characterization of rGO/CNT with amine derivative. ► Ultrasenstitive and specific detection of TNT. -- Abstract: Binding of electron-deficient trinitrotoluene (TNT) to the electron rich amine groups on a substrate form specific charge-transfer Jackson–Meisenheimer (JM) complex. In the present work, we report formation of specific JM complex on amine functionalized reduced graphene oxide/carbon nanotubes- (a-rGO/CNT) nanocomposite leading to sensitive detection of TNT. The CNT were dispersed using graphene oxide that provides excellent dispersion by attaching to CNT through its hydrophobic domains and solubilizes through the available -OH and -COOH groups on screen printed electrode (SPE). The GO was reduced electrochemically to form reduced graphene that remarkably increases electrochemical properties owing to the intercalation of high aspect CNT on graphene flakes as shown by TEM micrograph. The surface amine functionalization of dropcasted and rGO/CNT was carried out using a bi-functional cross linker ethylenediamine. The extent of amine functionalization on modified electrodes was confirmed using energy dispersive X-ray (EDX), X-ray photoelectron spectroscopy (XPS) and confocal microscopy. The FTIR and Raman spectra further suggested the formation of JM complex between amine functionalized electrodes and TNT leading to a shift in peak intensity together with peak broadening. The a-rGO/CNT nanocomposite prepared electrode surface leads to ultra-trace detection of TNT upto 0.01 ppb with good reproducibility (n = 3). The a-rGO/CNT sensing platform could be an alternate for sensitive detection of TNT explosive for various security and environmental applications.

  15. Grain Yield and Water Use Efficiency in Extremely-Late Sown Winter Wheat Cultivars under Two Irrigation Regimes in the North China Plain.

    Directory of Open Access Journals (Sweden)

    Bin Wang

    Full Text Available Wheat production is threatened by water shortages and groundwater over-draft in the North China Plain (NCP. In recent years, winter wheat has been increasingly sown extremely late in early to mid-November after harvesting cotton or pepper. To improve water use efficiency (WUE and guide the extremely late sowing practices, a 3-year field experiment was conducted under two irrigation regimes (W1, one-irrigation, 75 mm at jointing; W2, two-irrigation, 75 mm at jointing and 75 mm at anthesis in 3 cultivars differing in spike size (HS4399, small spike; JM22, medium spike; WM8, large spike. Wheat was sown in early to mid-November at a high seeding rate of 800-850 seeds m(-2. Average yields of 7.42 t ha(-1 and WUE of 1.84 kg m(-3 were achieved with an average seasonal evapotranspiration (ET of 404 mm. Compared with W2, wheat under W1 did not have yield penalty in 2 of 3 years, and had 7.9% lower seasonal ET and 7.5% higher WUE. The higher WUE and stable yield under W1 was associated with higher 1000-grain weight (TGW and harvest index (HI. Among the 3 cultivars, JM22 had 5.9%-8.9% higher yield and 4.2%-9.3% higher WUE than WM8 and HS4399. The higher yield in JM22 was attributed mainly to higher HI and TGW due to increased post-anthesis biomass and deeper seasonal soil water extraction. In conclusion, one-irrigation with a medium-sized spike cultivar JM22 could be a useful strategy to maintain yield and high WUE in extremely late-sown winter wheat at a high seeding rate in the NCP.

  16. Biochemical and immnulogical analysis of UV-induced photolesions

    International Nuclear Information System (INIS)

    Hoffen, A. van; Kalle, W.H.J.; Hazekamp, A.M.; Zeeland, A.A. van; Lohman, P.H.M.; Mullenders, L.H.F.

    1994-01-01

    The induction and removal of UV-induced photolesions was investigated in confluent human fibroblasts employing two different approaches. Photolyase and highly purified E. coli Uvr A,B and C proteins were used to measure the frequency of 6-4 photoproducts (6-4PP) in transcriptionally active and inactive genes. At a UV-dose range of 20-60 J/m 2 6-4PP were induced at about 4-fold lower frequency then cyclobutane pyrimidine dimers (CPD). In normal cells exposed to 30J/m 2 6-4PP were induced at about 4-fold lower frequency then cyclobutane pyrimidine dimers (CPD). In normal cells exposed to 30J/m 2 , the repair of 6-4PP was very rapid in both active and inactive genes when compared to CPD removal. No strand specific repair of 6-4PP in active genes was observed, although repair of 6-4PP occurred preferentially in the active genes when compared to inactive X-chromosomal genes. In xeroderma pigmentosum group C cells 6-4PP were selectively removed from the transcribed strand of active genes. In these cells the kinetics of repair of CPD and 6-4PP from the transcribed strand of active genes was very similar. Our results indicate that 6-4PP can be removed by a transcription coupled repair pathway, but that repair of 6-4PP by the global repair system is much more efficient. The sam conclusion can be drawn from studies aimed to determine BUdR labelled repair sites in genomic fragments. The results of these studies indicate a lack of strandspecific repair of 6-4 PP in active genes in normal cells at a relative low UV-dose of 10J/m 2

  17. Role of postreplication repair in transformation of human fibroblasts to anchorage independence

    International Nuclear Information System (INIS)

    Boyer, J.C.; Kaufmann, W.K.; Cordeiro-Stone, M.

    1991-01-01

    Cellular capacity for postreplication repair (PRR) and sensitivity to transformation to anchorage independence (AI) were quantified in normal foreskin and xeroderma pigmentosum (XP) variant fibroblasts after treatment with UV or benzo(a)pyrene-diol-epoxide I (BPDE-I). PRR is defined here as a collection of pathways that facilitate the replication of DNA damaged by genotoxic agents. It is recognized biochemically as the process by which nascent DNA grows longer than the average distance between two lesions in the DNA template. PRR refers more directly to the elimination of gaps in the daughter-strand DNA by mechanisms which remain to be determined for human cells, but which may include translesion replication and recombination. PRR was measured in diploid human fibroblasts by analysis of the dose kinetics for inhibition of DNA strand growth in carcinogen-treated cells. Logarithmically growing foreskin fibroblasts (NHF1) displayed D0 values of 4.3 J/m 2 and 0.14 microM for the inhibition of DNA synthesis in active replicons by UV and BPDE-I, respectively. XP variant cells (CRL1162) exhibited corresponding D0 values of 1.5 J/m 2 and 0.16 microM. The increased sensitivity to inhibition of DNA replication by UV in these XP variant fibroblasts (2.9-fold greater than normal) was mirrored by an enhanced frequency of transformation to AI. XP variant fibroblasts (CRL1162) were 3.2 times more sensitive to transformation to AI by UV than were the normal foreskin fibroblasts. As predicted by the PRR studies, both cell types exhibited similar frequencies of AI colonies induced by BPDE-I. Apparent thresholds were observed for induction of AI by UV (normal fibroblasts, 2.7 J/m 2 ; XP variant fibroblasts, 0.3 J/m 2 ) and BPDE-I (both, 0.05 microM)

  18. Controlled synthesis and photocatalytic properties of rhombic dodecahedral Ag3PO4 with high surface energy

    International Nuclear Information System (INIS)

    Xie, Yao; Huang, Zhaohui; Zhang, Zhijie; Zhang, Xiaoguang; Wen, Ruilong; Liu, Yangai; Fang, Minghao; Wu, Xiaowen

    2016-01-01

    Graphical abstract: The high amount of rhombic dodecahedral Ag 3 PO 4 particles with a high exposure of the {110} facets and high surface energy (the surface energy of the {110} facets was 1.31 J/m 2 , greater than that of the {100} facet (1.12 J/m 2 ).) exhibited excellent photocatalytic activity. - Highlights: • High contents of rhombic dodecahedral Ag 3 PO 4 photocatalysts are prepared. • Excessive EG can destroy the morphology of Ag 3 PO 4 in synthesis process. • The rhombic dodecahedral Ag 3 PO 4 exhibits high surface energy. • High surface energy implies high photocatalytic activity. - Abstract: In this study, a series of Ag 3 PO 4 photocatalysts with different contents of rhombic dodecahedral particles were prepared in one pot by a facile, novel hydrothermal method using ethylene glycol (EG), which served as both a morphology modifier and reducing agent. The effects of EG content on the morphologies of Ag 3 PO 4 photocatalysts were discussed. The photocatalytic activity of the Ag 3 PO 4 photocatalysts was evaluated by the degradation of methylene blue trihydrate under visible-light irradiation. With the use of 0.8% EG in the reaction solvent, the sample exhibited excellent photocatalytic activity, attributed to the high amount of rhombic dodecahedral Ag 3 PO 4 particles with a high exposure of the {110} facets and high surface energy. The surface energy of the {110} facets was 1.31 J/m 2 , greater than that of the {100} facet (1.12 J/m 2 ). However, with 1% EG in the reaction solvent, although the Ag 3 PO 4 photocatalysts were composed of a majority of rhombic dodecahedral Ag 3 PO 4 particles, tiny Ag particles formed from Ag + under the action of EG attached on the surface of the sample decreased the absorption of visible light, resulting in low photocatalytic activity.

  19. Amine functionalized graphene oxide/CNT nanocomposite for ultrasensitive electrochemical detection of trinitrotoluene

    International Nuclear Information System (INIS)

    Sablok, Kavita; Bhalla, Vijayender; Sharma, Priyanka; Kaushal, Roohi; Chaudhary, Shilpa; Suri, C. Raman

    2013-01-01

    Highlights: ► Binding of electron-deficient trinitrotoluene to the electron rich amino groups to form JM complexes. ► rGO/CNT based platform for enhanced electrochemical detection. ► Functionalization and characterization of rGO/CNT with amine derivative. ► Ultrasenstitive and specific detection of TNT. -- Abstract: Binding of electron-deficient trinitrotoluene (TNT) to the electron rich amine groups on a substrate form specific charge-transfer Jackson–Meisenheimer (JM) complex. In the present work, we report formation of specific JM complex on amine functionalized reduced graphene oxide/carbon nanotubes- (a-rGO/CNT) nanocomposite leading to sensitive detection of TNT. The CNT were dispersed using graphene oxide that provides excellent dispersion by attaching to CNT through its hydrophobic domains and solubilizes through the available -OH and -COOH groups on screen printed electrode (SPE). The GO was reduced electrochemically to form reduced graphene that remarkably increases electrochemical properties owing to the intercalation of high aspect CNT on graphene flakes as shown by TEM micrograph. The surface amine functionalization of dropcasted and rGO/CNT was carried out using a bi-functional cross linker ethylenediamine. The extent of amine functionalization on modified electrodes was confirmed using energy dispersive X-ray (EDX), X-ray photoelectron spectroscopy (XPS) and confocal microscopy. The FTIR and Raman spectra further suggested the formation of JM complex between amine functionalized electrodes and TNT leading to a shift in peak intensity together with peak broadening. The a-rGO/CNT nanocomposite prepared electrode surface leads to ultra-trace detection of TNT upto 0.01 ppb with good reproducibility (n = 3). The a-rGO/CNT sensing platform could be an alternate for sensitive detection of TNT explosive for various security and environmental applications

  20. Rapla taustaga inimesed teatrifestivali pildis / Margus Mikomägi

    Index Scriptorium Estoniae

    Mikomägi, Margus, 1956-

    2009-01-01

    Teatrifestivalist "Draama 2009" Tartus. Tartu Uue Teatri lavastusest "Elud", Tallinna Linnateatri lavastusest "Ohvrit mängides", Vanemuise teatri lavastusest "Loss", NO99 lavastusest "Pea vahetus" jm.

  1. Geschäfte der Aktiengesellschaft mit nahestehenden Personen und Unternehmen. Bestandsaufnahme und anstehende Neuerungen durch die Umsetzung der EU-Aktionärsrechterichtlinie II / Ursula Kleinert, Volker Mayer

    Index Scriptorium Estoniae

    Kleinert, Ursula

    2018-01-01

    Euroopa Liidu direktiivi (2017/828), mis käsitleb aktsionäride pikaajalise kaasamise soodustamist muudatuste mõjust Saksamaa aktsiaseltse, raamatupidamist, maksuõigust jm. puudutavatele õigusaktidele

  2. Shoulder MRI scan

    Science.gov (United States)

    ... exercises Rotator cuff - self-care Shoulder replacement - discharge Shoulder surgery - discharge Using your shoulder after replacement surgery References Hanypsiak B, DeLong JM, Lowe WR. Scapulothoracic ...

  3. Jan Hoet : " Magritte ja Ensor - ühtaegu Valloonia ja Flandria keskpunkt" : Hermine Bokhorsti intervjuu Jan Hoetiga / Jan Hoet ; interv. Hermine Bokhorst, tõlk. Tamara Luuk

    Index Scriptorium Estoniae

    Hoet, Jan

    2002-01-01

    Tänapäevasest belgia kunstist, flaami ja vallooni kunstniku lähenemisviisidest, kunstnike toetamisest, Flandria ja frankofoonse Belgia muuseumipoliitika erinevusest, belglaste tundlikkusest kunsti suhtes jm.

  4. Algirdas Brazauskas : Ma ei häbene rahvale oma liini näidata / Algirdas Brazauskas ; interv. Sirje Pärismaa

    Index Scriptorium Estoniae

    Brazauskas, Algirdas, 1932-2010

    2001-01-01

    Taasiseseisvunud Leedu esimene president oma ametiaja suurimatest saavutustest, oma edu saladusest, muutustest Leedu ühiskonnas, Balti riikide ühtsusest, Leedu-Vene suhetest, kokkupuudetest Eestiga jm. Eluloolisi andmeid

  5. Teel Euroopa Raamatukogu poole / Toomas Schvak

    Index Scriptorium Estoniae

    Schvak, Toomas

    2005-01-01

    Projektist TEL-ME-MOR, eesmärgist luua üleeuroopaline raamatukoguteenus, mis võimaldaks ühist juurdepääsu Euroopa Liidu liikmesriikide rahvusraamatukogude elektronkataloogidele jm. andmekogudele

  6. Audition of Professor Jean-Marie Chevalier (Paris 9 univ. Dauphine) at the end of the FNCCR board meeting of July 9, 2003

    International Nuclear Information System (INIS)

    2003-12-01

    This document presents the economic analysis made by a university specialist, J.M. Chevalier, about the evolution of the energy systems in France and abroad. This analysis was made at the end of the July 9, 2003 board meeting of the National federation of granted organizations and public corporations (FNCCR). In his analysis, J.M. Chevalier presents: the un-bundling between energy generation and transportation (separation between network manager and network user, separation between transport functions (natural monopoly) and commercial functions), the advantages and drawbacks of energy markets opening, the role of a regulation authority, the public utility aspect, the security of supplies with the lack of new investments and the manipulation of prices. At the end of his presentation, J.M. Chevalier answers a series of questions about the volatility of the electricity market, the balance between monopoly and competition, the lack of a real European energy policy, the public acceptance with respect to new project of power line, the development of decentralized power generation and wind energy in the context of market deregulation, the opening of Electricite de France (EdF) and Gaz de France (GdF) capital, and the impact of deregulation on small consumers. (J.S.)

  7. प्राचीन सभ्यता के विकास एवं विनाश मे जलवायु का योगदान: पुरातात्विक अवशेषो पर आधारित एक अध्ययन

    Digital Repository Service at National Institute of Oceanography (India)

    Gaur, A.S.

    Zme ‘| Obdm`w H$m `moJXmZ… nwamVmpËdH$ Adeofm| na AmYm[aV EH$ AÜ``Z E A{ZéÕ {g§h Jm¡a gmam§e Obdm`w n[adV©Z EH$ {Za§Va à{H«$`m h¡ Am¡a Bgr {gÕm§V na AmYm[aV h¢ X¡{ZH$ Ed§ dm{f©H$ n[adV©Z & bo{H$Z `h n[adV©Z n¥Ïdr na ahZo dmbo Ord-OÝVw {OZ...§ {dXoer gm{hË`m| ‘| {H$gr ‘mZd g§ñH¥${V Ho$ {dZme Ho$ {ddaU {‘bVo h¢ Am¡a CgH$o à‘wI H$maU Ho$ ê$n ‘| n¥Ïdr na Am`r ^`§H$a àb` H$m C„oI {H$`m J`m h¡& H$hm OmVm h¡ {H$ n¥Ïdr na BVZm A{YH$ nmZr ~‹T> J`m Wm {H$ Am{X ‘mZd H$mo {h‘mb` ‘| eaU boZr n‹S>r Wr...

  8. Synergistic Effect of Nitrogen Doping and MWCNT Intercalation for the Graphene Hybrid Support for Pt Nanoparticles with Exemplary Oxygen Reduction Reaction Performance

    Directory of Open Access Journals (Sweden)

    Kang Fu

    2018-04-01

    Full Text Available The potential of graphene–multi-walled-carbon nanotube (G-M hybrids prepared by the one-pot modified Hummers method followed by thermal annealing has been demonstrated by employing one as an electrocatalyst support for oxygen reduction reaction (ORR. N doping effectively modified the electronic structure of the G-M hybrid support, which was beneficial for the uniform distribution of Pt nanoparticles, and ORR activities were further improved. The newly prepared Pt/N-G-M catalyst demonstrated higher electrochemical activity than Pt/G-M and Pt/G catalysts. Even compared with commercial 20 wt % Pt/C (JM20, Pt/N-G-M delivered a better half-wave potential and mass activity. In terms of the durability test, Pt/N-G-M maintained 72.7% of its initial electrochemical active surface area (ECSA after 2000 repeated potential cycles between 0 and 1.2 V in acidic media in relation to the 44.4% retention for JM20. Moreover, the half-wave potential for Pt/N-G-M showed only a minimal change, significantly superior to the 139 mV of loss for JM20. It is expected that Pt/N-G-M can be the potential candidate as a highly efficient and durable catalyst if utilized in proton exchange membrane fuel cells (PEMFCs.

  9. DNA replication and repair of Tilapia cells: Pt. 2

    International Nuclear Information System (INIS)

    Chen, J.D.; Yew, F.H.

    1988-01-01

    TO-2 is a fish cell line derived from the Tilapia ovary. It grows over a wide range of temperature (15-34 0 C). We report the effects of temperature on DNA replication and u.v. repair in TO-2 cells. When the cells were moved from 31 0 C to the sublethal high temperature of 37 0 C, the rate of DNA synthesis first decreased to 60%, then speedy recovery soon set in, and after 8h at 37 0 C the rate of DNA synthesis overshot the 31 0 C control level by 180%. When moved to low temperature (18 0 C) Tilapia cells also showed an initial suppression of DNA synthesis before settling at 30% of the control level. U.V. reduced but could not block DNA synthesis completely. The inhibition was overcome in 3h at 37, 31 and 25 0 C, but not at 18 0 C. Initiation of nascent DNA synthesis was blocked at 4Jm -2 in TO-2 cells compared with ≤ 1Jm -2 in mammalian cells. After 9Jm -2 u.v. irradiation, low molecular weight DNA replication intermediates started to accumulate. TO-2 cells showed low levels of u.v.-induced excision repair. (author)

  10. Contribution of Kunitz protease inhibitor and transmembrane domains to amyloid precursor protein homodimerization.

    Science.gov (United States)

    Ben Khalifa, N; Tyteca, D; Courtoy, P J; Renauld, J C; Constantinescu, S N; Octave, J N; Kienlen-Campard, P

    2012-01-01

    The two major isoforms of the human amyloid precursor protein (APP) are APP695 and APP751. They differ by the insertion of a Kunitz-type protease inhibitor (KPI) sequence in the extracellular domain of APP751. APP-KPI isoforms are increased in Alzheimer's disease brains, and they could be associated with disease progression. Recent studies have shown that APP processing to Aβ is regulated by homodimerization, which involves both extracellular and juxtamembrane/transmembrane (JM/TM) regions. Our aim is to understand the mechanisms controlling APP dimerization and the contribution of the ectodomain and JM/TM regions to this process. We used bimolecular fluorescence complementation approaches coupled to fluorescence-activated cell sorting analysis to measure the dimerization level of different APP isoforms and APP C-terminal fragments (C99) mutated in their JM/TM region. APP751 was found to form significantly more homodimers than APP695. Mutation of dimerization motifs in the TM domain of APP or C99 did not significantly affect fluorescence complementation. These findings indicate that the KPI domain plays a major role in APP dimerization. They set the basis for further investigation of the relation between dimerization, metabolism and function of APP. Copyright © 2012 S. Karger AG, Basel.

  11. Hierarchy compensation of non-homogeneous intermittent atmospheric turbulence

    Science.gov (United States)

    Redondo, Jose M.; Mahjoub, Otman B.; Cantalapiedra, Inma R.

    2010-05-01

    In this work a study both the internal turbulence energy cascade intermittency evaluated from wind speed series in the atmospheric boundary layer, as well as the role of external or forcing intermittency based on the flatness (Vindel et al 2008)is carried out. The degree of intermittency in the stratified ABL flow (Cuxart et al. 2000) can be studied as the deviation, from the linear form, of the absolute scaling exponents of the structure functions as well as generalizing for non-isotropic and non-homogeneous turbulence, even in non-inertial ranges (in the Kolmogorov-Kraichnan sense) where the scaling exponents are not constant. The degree of intermittency, evaluated in the non-local quasi-inertial range, is explained from the variation with scale of the energy transfer as well as the dissipation. The scale to scale transfer and the structure function scaling exponents are calculated and from these the intermittency parametres. The turbulent diffusivity could also be estimated and compared with Richardson's law. Some two point correlations and time lag calculations are used to investigate the time and spatial integral length scales obtained from both Lagrangian and Eulerian correlations and functions, and we compare these results with both theoretical and laboratory data. We develop a theoretical description of how to measure the different levels of intermittency following (Mahjoub et al. 1998, 2000) and the role of locality in higher order exponents of structure function analysis. Vindel J.M., Yague C. and Redondo J.M. (2008) Structure function analysis and intermittency in the ABL. Nonlin. Processes Geophys., 15, 915-929. Cuxart J, Yague C, Morales G, Terradellas E, Orbe J, Calvo J, Fernández A, Soler M R, Infante C, Buenestado P, Espinalt A, Joergensen H E, Rees J M, Vilá J, Redondo J M, Cantalapiedra R and Conangla L (2000): Stable atmospheric boundary-layer experiment in Spain (Sables 98): a report, Boundary-Layer Meteorology 96, 337-370 Mahjoub O

  12. The role of Cra in regulating acetate excretion and osmotic tolerance in E. coli K-12 and E. coli B at high density growth.

    Science.gov (United States)

    Son, Young-Jin; Phue, Je-Nie; Trinh, Loc B; Lee, Sang Jun; Shiloach, Joseph

    2011-06-30

    E. coli B (BL21), unlike E.coli K-12 (JM109) is insensitive to glucose concentration and, therefore, grows faster and produces less acetate than E. coli K-12, especially when growing to high cell densities at high glucose concentration. By performing genomic analysis, it was demonstrated that the cause of this difference in sensitivity to the glucose concentration is the result of the differences in the central carbon metabolism activity. We hypothesized that the global transcription regulator Cra (FruR) is constitutively expressed in E. coli B and may be responsible for the different behaviour of the two strains. To investigate this possibility and better understand the function of Cra in the two strains, cra - negative E. coli B (BL21) and E. coli K-12 (JM109) were prepared and their growth behaviour and gene expression at high glucose were evaluated using microarray and real-time PCR. The deletion of the cra gene in E. coli B (BL21) minimally affected the growth and maximal acetate accumulation, while the deletion of the same gene in E.coli K-12 (JM109) caused the cells to stop growing as soon as acetate concentration reached 6.6 g/L and the media conductivity reached 21 mS/cm. ppsA (gluconeogenesis gene), aceBA (the glyoxylate shunt genes) and poxB (the acetate producing gene) were down-regulated in both strains, while acs (acetate uptake gene) was down-regulated only in E.coli B (BL21). These transcriptional differences had little effect on acetate and pyruvate production. Additionally, it was found that the lower growth of E. coli K-12 (JM109) strain was the result of transcription inhibition of the osmoprotectant producing bet operon (betABT). The transcriptional changes caused by the deletion of cra gene did not affect the activity of the central carbon metabolism, suggesting that Cra does not act alone; rather it interacts with other pleiotropic regulators to create a network of metabolic effects. An unexpected outcome of this work is the finding that cra

  13. 75 FR 15711 - Government-Owned Inventions; Availability for Licensing

    Science.gov (United States)

    2010-03-30

    .... Development of assisted reproduction technologies. Studies of early embryonic development. Development Status..., W Gong, P Proost, J Van Damme, WJ Murphy, and JM Wang. Bacterial lipopolysaccharide selectively up...

  14. Suvi õues / Ivi-Els Schneider

    Index Scriptorium Estoniae

    Schneider, Ivi-Els, 1945-

    2004-01-01

    Õuemööblit Eesti kodudest. 9 ill.: Verner Pantoni kavandatud plastiktool, Albero Medea kavandatud lamamistool, dirigent Tõnu Kaljuste pink mererannas, viljapeksumasina hammasrattast laud, puust kiikhobune jm.

  15. Ettekäändeks "Romeo ja Julia" / Mai Murdmaa, Lloyd Sobel, Charles Cusick Smith ; interv. Kristiina Garancis

    Index Scriptorium Estoniae

    Murdmaa, Mai, 1938-

    1998-01-01

    13. veebr. 1998 "Estonia" teatris esietendunud balleti "Romeo ja Julia" lavastusmeeskonna liikmed esietendunud tantsuetenduse teemadel. C. C. Smith oma vabaloomingust. L. Sobel oma tööprotsessist jm

  16. Verine lugu Tallinna abilinnapea minevikust / Sulev Vedler

    Index Scriptorium Estoniae

    Vedler, Sulev, 1970-

    2011-01-01

    1999. a. plahvatas Mihhail Kõlvarti, Tallinna praeguse abilinnapea autos pomm, läbiotsimisel leiti tema kodunt laskemoona, kärbik, hulk politsei vormiriideid jm. Politsei kahtlustas Kõlvartit seotuses allilmaga

  17. Ettepanekud : Tartu, 28. aprill 2010 = Proposals : Tartu, 28 April 2010

    Index Scriptorium Estoniae

    2011-01-01

    Tartu linnafoorumil tehtud ettepanekud. Tartu kesklinn kui kampus, ülikooli hoonete paiknemine. Linna jätkusuutlik areng. Geograafilised identiteedid: Emajõgi ja Toomemägi. Olulised tegevused linnaplaneerimises jm.

  18. Eredamaid helielamusi Helsingi "Avanto'lt" / Rael Artel

    Index Scriptorium Estoniae

    Artel, Rael, 1980-

    2003-01-01

    Helsingi meediakunsti festival 21.-24. 2002. Põhitähelepanu oli koondunud helile. Franz Pomassli heliinstallatsioonist, Briti loomingulise kollektiivi Semiconductor heli- ja pildiperformance'itest, inglise kunstniku Lis Rhodesi videotest jm.

  19. Business full of optimism

    Index Scriptorium Estoniae

    2004-01-01

    Ülevaade reklaamindusest Baltimaades - ideede leidmine, töötajate professionaalsus, turu kujunemine, integreeritud turunduse teenus jm. Tabelid: Eesti ja Leedu agentuuride reiting ; Töötajate arv reklaamiagentuurides 2003

  20. Feministlikul mõttel on koht meie kunstiajalugudes : intervjuu kunstiakadeemia dotsendi Katrin Kivimaaga : feminism / Katrin Kivimaa ; interv. Reet Varblane

    Index Scriptorium Estoniae

    Kivimaa, Katrin, 1969-

    2004-01-01

    Feministlikust kunstist ja kunstimõttest Eestis, feminismi mõistmisest Ungaris ja Inglismaal, muutustest eesti ühiskonnas võrdõiguslikkuse mõttes, uue feministliku kunstimõtte kogumiku ilmumise vajalikkusest jm.

  1. Iraanlane Homayun Ghanizadeh lavastab Tallinnas "Antigonet" / Homayun Ghanizadeh ; intervjueerinud Andres Laasik

    Index Scriptorium Estoniae

    Ghanizadeh, Homayun

    2010-01-01

    11. augustil Tallinna Püha Katariina kirikus esietenduva "Antigone" (Sophokles / Homayun Ghanizadeh) lavastaja Homayun Ghanizadeh tööst Eestis, eesti ja iraani teatrist, näitlejatest, teatri mainest jm.

  2. Steven Spielberg hädas Peeter Paaniga / Timo Diener

    Index Scriptorium Estoniae

    Diener, Timo

    2004-01-01

    Steven Spielbergi raskused J.M. Barrie "Peeter Paani" ekraniseerimisel, tulemuseks mängufilm "Hook" : Ameerika Ühendriigid 1991. Järgneb 16. aug. 2004, lk. 38 pealkirja all "Rahulolematu Steven Spielberg"

  3. Priit Põldme podnimajet reiting / Ell-Maaja Randküla

    Index Scriptorium Estoniae

    Randküla, Ell-Maaja, 1939-2016

    2005-01-01

    28. X 2004. a. Eesti Sisearhitektide Liidu esimeheks valitud Priit Põldmest ja tema loomingust. P. Põldme eesti sisearhitektuuri maine tõusust Eestis, minimalismist kodukujunduses, ESL-i tulevikuplaanidest jm. 4 ill

  4. Childhood Origins of Tolerance for Dissent

    Science.gov (United States)

    Zellman, Gail L.; Sears, David O.

    1971-01-01

    Reports questionnaire data from 1384 children in grades five through nine. Reveals that political socialization of attitudes toward free speech apparently does occur during late childhood and early adolescence. (JM)

  5. Eestil oma Art Director's Club

    Index Scriptorium Estoniae

    2003-01-01

    ADCE on Euroopa klubi täieõiguslik liige. ADC on mittetulunduslik organisatsioon, mille eesmärk on hoogustada ja toetada loovust reklaamis, disainis, filminduses, fotonduses jm., korraldab reklaamivõistlusi

  6. Plant guide: Barestem biscuitroot: Lomatium nudicaule (Pursh) J.M. Coult. and Rose

    Science.gov (United States)

    Derek Tilley; Loren St. John

    2012-01-01

    Barestem biscuitroot is palatable primarily to sheep but grows in such limited quantities that it is hardly an important forage species (Hermann 1966). It serves as a host plant for the larvae of anise swallowtail butterfly (Papilio zelicaon) (Pelini et al 2009).

  7. Anthony J.M. Nazombe In L8.byrinths,1 Christopher Okigbo traces ...

    African Journals Online (AJOL)

    This is indicated clearly by the poet's recollections of childhood memories as they ... He also draws attention to an Ibo equivalent: (. ..... Okigbo's most explicit statement so far concerning art as ritual and a ... And her shell, they divided. (p. 33).

  8. Jména studánek na Moravě a ve Slezsku

    Czech Academy of Sciences Publication Activity Database

    Komárková, Zina

    2010-01-01

    Roč. 51, č. 1 (2010), s. 227-246 ISSN 1211-4413 R&D Projects: GA ČR GA405/08/0703 Institutional research plan: CEZ:AV0Z90610518 Keywords : small water sources * hydronyms * word-formation * motivation Subject RIV: AI - Linguistics

  9. Nonlinear Eulerian Thermoelasticity for Anisotropic Crystals

    Science.gov (United States)

    2013-08-01

    related by AiJkL ¼ ∂ðFkMSMLÞ=∂FiJ ¼ FiNFkMCNJML þ δikSJL ¼ FiNFkMCNJML þ δikF−1Jn PnL : ð2:50Þ Similarly, coefficients A and Ĉ are related by AiJkL...IJKL ¼ F−1Ii F−1MiF−1Jj F−1Nj F−1Kk F−1OkF−1Ll F−1Pl ĈMNOP−F−1Ik F−1Kk F−1Jn PnL −F−1Ii F−1KmF−1JmPiL−F−1Ii F−1KmF−1Li PmJ−F−1Ii F−1Jm F−1LmPiK : ð2:52Þ

  10. Linear coupling of electromagnetic and Jeans modes in self-gravitating plasma streams

    International Nuclear Information System (INIS)

    Yaroshenko, Victoria V.; Voitenko, Yuriy; Goossens, Marcel

    2002-01-01

    A new mechanism of linear coupling between electromagnetic (nonpotential) and gravitational disturbances is found for oblique propagation relatively to particle streams. The general dispersion law is derived and applied to the case of two countersteaming dust beams of equal strength and quiasiperpendicular propagation. It reveals a strong linear coupling between the low-frequency aperiodically unstable electromagnetic (AEM) and the Jeans (JM) modes. The coupling is of a mode conversion type, resulting in a frequency gap in the dispersion, and thus significantly modifies the instability criteria. It is shown that, in contrast to the electrostatic case, AEM and JM coupling in streaming self-gravitating plasmas can actually appear even if the plasma frequencies of the dust species greatly exceed the corresponding Jeans frequencies

  11. Taani kunsti kuldaeg / Finn Termann Frederiksen ; interv. Kadi Polli

    Index Scriptorium Estoniae

    Frederiksen, Finn Termann

    1999-01-01

    Eesti Kunstimuuseumis näitus "Kuldajast modernismini : Taani maalikunst 1830-1930". Randersi kunstimuuseumi direktor Finn Terman Frederiksen muuseumi kogudest, taani kuldaja kunstist, silmapaistvamatest kunstnikest, kirjanduskriitik Georg Brandesi rollist taani kunstis jm

  12. In vitro dermal absorption of decabromodiphenyl ethane in rat and human skin

    Data.gov (United States)

    U.S. Environmental Protection Agency — In vitro dermal absorption of decabromodiphenyl ethane in rat and human skin. This dataset is associated with the following publication: Knudsen, G., J.M. Sanders,...

  13. Disease: H01068 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available as mainly been associated with endocarditis, brain abscesses, vertebral osteomyel...g) ... AUTHORS ... Coll-Vinent B, Suris X, Lopez-Soto A, Miro JM, Coca A ... TITLE ... Haemophilus paraphrophilus endocarditis

  14. Suured ja Vannutatud : Kumu / Sirje Helme

    Index Scriptorium Estoniae

    Helme, Sirje, 1949-

    2006-01-01

    Vastuseks Raoul Kurvitza artiklile "Kumu : väited ja teesid" samas lehes lk. 11-12. Ajaloo ja kunstiajaloo ümberkirjutamisest, mõistetest "rahvus", "rahvusriik". Rahvuslikust kunstist, rahvuslikust identiteedist, valitud kuraatoritest jm.

  15. Luzern saab uue kontserdimaja

    Index Scriptorium Estoniae

    1998-01-01

    Mais algavad Luzerni uue kontserdisaali akustiliste jm. näitajate testkontserdid. Uuest kontserdisaalist saab ka Luzerni kuulsate rahvusvaheliste festivalide pealava nii suvel kui lihavõtte aegu. Arhitekt Jean Nouvel, akustik Russell Johnson.

  16. Linnade lömastavast hoost / Karin Paulus

    Index Scriptorium Estoniae

    Paulus, Karin, 1975-

    2004-01-01

    Arhitektuuriteadlase Andres Kure abiga koostatud linnatemaatikale keskendunud "Vikerkaare" erinumbrist (2004, 4-5). Michel de Certeau, Walter Benjamini, Jean-Paul Sartre, Boris Groysi, Jan Kausi ja Mart Kalmu artiklitest, Arne Maasiku fotodest jm.

  17. Vocational Education with a Twist: This School Teaches Community Service.

    Science.gov (United States)

    Lewis, Barbara

    1983-01-01

    At Davis Vocational Technical High School in Lincoln (Rhode Island) students in such areas as carpentry, culinary arts, and cosmetology provide free services to the community and gain valuable experience. (Author/JM)

  18. Euroopa kultuuripealik 2011 (Tallinn) lõpuks leitud / Mikko Fritze ; interv. Kaarel Tarand

    Index Scriptorium Estoniae

    Fritze, Mikko, 1963-

    2007-01-01

    Tallinn on Euroopa 2011. a. kultuuripealinn. Intervjuu korraldava sihtasutuse tegevjuhi Mikko Fritzega. Tegevusprogrammist, ka infrastruktuuri projektidest (linnateater, Kultuurikatel, rannapromenaad, lauluväljak, linnahall) jm. SA bürool on kavatsus kolida Kultuurikatlasse

  19. Хомаюн Гханизадех: когда актеры хороши, у режиссера вырастают крылья / Хомаюн Гханизадех ; интервьюировал Борис Тух

    Index Scriptorium Estoniae

    Гханизадех, Хомаюн

    2010-01-01

    11. augustil Tallinna Püha Katariina kirikus esietendunud "Antigone" (autorid: Sophokles / Homayun Ghanizadeh) lavastaja Homayun Ghanizadeh tööst Eestis, eesti ja iraani teatrist, näitlejatest, iraani teatri mainest jm.

  20. Konsolidation und Stoffaustrag von Aufbereitungsrueckstaendendes Uranerzbergbaus

    Czech Academy of Sciences Publication Activity Database

    Beyer, K. D.; Herrmann, R.; Ohlendorf, F.; Sembdner, T.; von Wolffersdorff, P. A.; Herle, Ivo; Kolymbas, D.

    2001-01-01

    Roč. 24, č. 4 (2001), s. 253-262 ISSN 0172-6145 Institutional research plan: CEZ:AV0Z2071913 Keywords : consolidation, solute transport, uranium mill tailings. Subject RIV: JM - Building Engineering

  1. A Reaction Involving Oxygen and Metal Sulfides.

    Science.gov (United States)

    Hill, William D. Jr.

    1986-01-01

    Describes a procedure for oxygen generation by thermal decomposition of potassium chlorate in presence of manganese dioxide, reacted with various sulfides. Provides a table of sample product yields for various sulfides. (JM)

  2. Lähtugem ehitistest! / William J. R. Curtis ; interv. Andres Kurg, Karin Hallas, Triin Ojari

    Index Scriptorium Estoniae

    Curtis, William J. R.

    1998-01-01

    24. apr. pidas Rotermanni soolalaos loengu arhitektuuriajaloolane William J. R. Curtis. Katkeid jutuajamisest W. Curtisega. Arhitektuurikriitikast, oma raamatust "Modern Architecture since 1900", millest W. Curtis praegu kriitikuna kirjutab, Lille'i projektist jm

  3. Hans Lepp : ainult tänu kodueestlastele on Eesti olemas / Hans Lepp ; interv. Kalev Vilgats

    Index Scriptorium Estoniae

    Lepp, Hans, 1950-

    2007-01-01

    Rootsi instituudi praegune kultuurinõunik Hans Lepp töötas esimese kultuuriatasheena taas avatud Rootsi suursaatkonnas. Töötamisest Rootsi instituudis, riigi välispoliitikast, suhetest Venemaaga, aprillisündmustest jm

  4. 2018-02-21T08:16:23Z https://www.ajol.info/index.php/all/oai oai:ojs ...

    African Journals Online (AJOL)

    ... JM Kruger, HA Network flow models, integer linear programming, extended tree ... such as telecommunication, logistics, engineering and computer science. ... Following on an overview of the pipeline design problem, the extended tree ...

  5. Kõrge kvantiteediga KanaNahk / Margus Kiis

    Index Scriptorium Estoniae

    Kiis, Margus

    2002-01-01

    Rahvusvahelisest kunstiüritusest KanaNahk 2002 Rakveres. Ülevaatlik kirjeldus üritusel osalenud kunstnike töödest: perfomanced, installastsioonid, videoperfomanced, etendused, videod jm. Järgneb 3. ja 10. aug. 2002

  6. PHYLOGENETIC ANALYSIS AND AUTECOLOGY OF SPORE-FORMING BACTERIA FROM HYPERSALINE ENVIRONMENTS.

    Science.gov (United States)

    Gladka, G V; Romanovskaya, V A; Tashyreva, H O; Tashyrev, O B

    2015-01-01

    Multi-resistant to extreme factors spore-forming bacteria of Bacillus genus are isolated from hypersaline environments of the Crimea (Ukraine) and the Dead Sea (Israel). Phylogenetic analysis showed distinction of dominating extremophilic culturable species in studied regions. In Crimean environments they are B. mojavensis and B. simplex, in the Dead Sea ecosystem--B. subtilis subsp. spizizenii, B. subtilis subsp. subtilis, B. licheniformis and B. simplex. Isolates are simultaneously halotolerant and resistant to UV radiation. Strains isolated from the Dead Sea and the Crimea environments were resistant to UV: LD90 and LD99.99 made 100-170 J/m2 and 750-1500 J/m2 respectively. Spores showed higher UV-resistance (LD99.99-2500 J/m2) than the vegetative cells. However the number of spores made 0.02-0.007% of the whole cell population, and should not significantly affect the UV LD99.99 value. Isolates of both environments were halotolerant in the range of 0.1-10% NaCl and thermotolerant in the range of 20-50 °C, and didn't grow at 15 °C. Survival strategy of spore-forming bacteria from hypersaline environments under high UV radiation level can be performed by spore formation which minimize cell damage as well as efficient DNA-repair systems that remove damages.

  7. DNA replication and repair of Tilapia cells: Pt. 2. Effects of temperature on DNA replication and ultraviolet repair in Tilapia ovary cells

    Energy Technology Data Exchange (ETDEWEB)

    Chen, J.D.; Yew, F.H.

    1988-02-01

    TO-2 is a fish cell line derived from the Tilapia ovary. It grows over a wide range of temperature (15-34/sup 0/C). We report the effects of temperature on DNA replication and u.v. repair in TO-2 cells. When the cells were moved from 31/sup 0/C to the sublethal high temperature of 37/sup 0/C, the rate of DNA synthesis first decreased to 60%, then speedy recovery soon set in, and after 8h at 37/sup 0/C the rate of DNA synthesis overshot the 31/sup 0/C control level by 180%. When moved to low temperature (18/sup 0/C) Tilapia cells also showed an initial suppression of DNA synthesis before settling at 30% of the control level. U.V. reduced but could not block DNA synthesis completely. The inhibition was overcome in 3h at 37, 31 and 25/sup 0/C, but not at 18/sup 0/C. Initiation of nascent DNA synthesis was blocked at 4Jm/sup -2/ in TO-2 cells compared with less than or equal to 1Jm/sup -2/ in mammalian cells. After 9Jm/sup -2/ u.v. irradiation, low molecular weight DNA replication intermediates started to accumulate. TO-2 cells showed low levels of u.v.-induced excision repair.

  8. Sol-gel bonding of silicon wafers

    International Nuclear Information System (INIS)

    Barbe, C.J.; Cassidy, D.J.; Triani, G.; Latella, B.A.; Mitchell, D.R.G.; Finnie, K.S.; Short, K.; Bartlett, J.R.; Woolfrey, J.L.; Collins, G.A.

    2005-01-01

    Sol-gel bonds have been produced between smooth, clean silicon substrates by spin-coating solutions containing partially hydrolysed silicon alkoxides. The two coated substrates were assembled and the resulting sandwich fired at temperatures ranging from 60 to 600 deg. C. The sol-gel coatings were characterised using attenuated total reflectance Fourier transform infrared spectroscopy, ellipsometry, and atomic force microscopy, while the corresponding bonded specimens were investigated using scanning electron microscopy and cross-sectional transmission electron microscopy. Mechanical properties were characterised using both microindentation and tensile testing. Bonding of silicon wafers has been successfully achieved at temperatures as low as 60 deg. C. At 300 deg. C, the interfacial fracture energy was 1.55 J/m 2 . At 600 deg. C, sol-gel bonding provided superior interfacial fracture energy over classical hydrophilic bonding (3.4 J/m 2 vs. 1.5 J/m 2 ). The increase in the interfacial fracture energy is related to the increase in film density due to the sintering of the sol-gel interface with increasing temperature. The superior interfacial fracture energy obtained by sol-gel bonding at low temperature is due to the formation of an interfacial layer, which chemically bonds the two sol-gel coatings on each wafer. Application of a tensile stress on the resulting bond leads to fracture of the samples at the silicon/sol-gel interface

  9. Molecular approaches to contraceptive development

    Indian Academy of Sciences (India)

    Unknown

    drugs; PACAP, pituitary adenyl cyclase activating peptide; PK, progesterone receptor; RA, retinoic acid. ... Institute for Research in Reproduction, JM Street, Parel, Mumbai 400 012, India .... antagonistic properties devoid of side effects such as.

  10. Bulk Leisure--Problem or Blessing?

    Science.gov (United States)

    Beland, Robert M.

    1983-01-01

    With an increasing number of the nation's work force experiencing "bulk leisure" time because of new work scheduling procedures, parks and recreation offices are encouraged to examine their program scheduling and content. (JM)

  11. A Structured Approach to Teaching Applied Problem Solving through Technology Assessment.

    Science.gov (United States)

    Fischbach, Fritz A.; Sell, Nancy J.

    1986-01-01

    Describes an approach to problem solving based on real-world problems. Discusses problem analysis and definitions, preparation of briefing documents, solution finding techniques (brainstorming and synectics), solution evaluation and judgment, and implementation. (JM)

  12. Marine Science

    African Journals Online (AJOL)

    The local communities' eco- nomic activities involve fishing, seaweed farming and ..... and body composition of Nile tilapia (Oreochromis niloticus) fingerlings. ... King JM, Brown CA (2006) River Health Assessment. IUCN Water and Nature ...

  13. The Past is Present / Mika Hannula

    Index Scriptorium Estoniae

    Hannula, Mika

    1998-01-01

    Ajaloosündmuste interpreteerimisest kaasaegsete poolt, selle subjektiivsusest. Vaidlus Holocausti memoriaali üle Berliinis, Moskva 850. aastapäeva tähistamine, 'Estonia' hukule pühendatud monumendi püstitamine Stockholmi jm

  14. Nii kauge, kuid nii omane Brasiilia / Antonio Claudio Carvalho ; interv. Reet Varblane

    Index Scriptorium Estoniae

    Carvalho, Antonio Claudio

    2005-01-01

    Vestlus brasiilia kunstniku Antonio Claudio Carvalhoga 15. X, päeval pärast tema näituse avamist Kunstihoone galeriis. Kunstist, kunstnikest, endast, oma loomingust, kunsti tähendusest praeguses Brasiilias jm.

  15. The Trickster, the Bad Nigga, and the New Urban Ethnography: An Initial Report and Editorial Coda

    Science.gov (United States)

    Milner, Richard B.

    1972-01-01

    The author first describes a new way of doing ethnographic research, contrasting it with the prevalent academic style, and then discusses the studies of black prostitution done by him and his wife. (JM)

  16. The Economics of Minorities

    Science.gov (United States)

    Coles, Flournoy A., Jr.

    1973-01-01

    This article discusses some of the more important economic problems of minorities in the United States, identifying the economics of minorities with the economics of poverty, discrimination, exploitation, urban life, and alienation. (JM)

  17. Zone Denmark - gasell Taanist / Reet Krause

    Index Scriptorium Estoniae

    Krause, Reet, 1967-

    2006-01-01

    Taanis Viborgis asuva firma Zone Company Denmark, kaubamärgi Zone Denmark ja firma disainerite tutvustus. Ettevõte valmistab disainitooteid roostevabast terasest, klaasist, puidust, kummist jm. Disainer Naja Utzon Popov endast, oma loomingust

  18. Convective thermal fluxes in unsteady non-homogeneous flows generating complex three dimensional vorticity patterns

    Science.gov (United States)

    Tellez Alvarez, Jackson David; Redondo, Jose Manuel; Sanchez, Jesu Mary

    2016-04-01

    estimate dominant mixing structures as well as the basic instabilities than drive the turbulent direct and inverse cascades [12]. References [1] Mahjoub O.B.; Redondo J.M.; and Babiano A. (2000). Hyerarchy flux in nonhomogeneous flows in turbulent diffusion in the environment Eds. Redondo J.M. and Babiano A. 249-260. [2] Redondo J.M. (1992). Termodinámica de los procesos irreversibles, efectos termoeléctricos. Rev. Termoelectricidad2, 16-29. AIT. Pamplona. [3] Dalziel, S. B. (1994). Perturbations and coherent flow in Rayleigh-Taylor instability in 4th International Workshop on the Physics of Compressible Turbulent Mixing, ed. P. F. Linden, D. L. Youngs, & S. B. Dalziel; 32-41. [4] Redondo J.M.; Sanchez J.M.; Pascual I.; Noriega, G.F. (1995). Thermoelectric regulation for electric cabinets: XVI International Conference in Thermoelectrics, 02-G20. Ed. V. Vedernikov. 456-468. St. Petersburg, Russia. [5] Mahjoub, O.B; Redondo J.M.; Babiano A. (1998).Structure functions in complex flows: Applied Scientific Research. 59, 299-313. Kluwer. [6] Matulka A.; Redondo J. M.; and Carrillo A. (2008). Experiments in stratified and rotating decaying 2D flows, Il Nuovo Cimento 31, 5-6, 757-770. 2008. [7] Redondo, J.M.; Tellez, J; Sotillos, L.; Gonzalez-Nieto, Pilar L.; Sanchez, J.M.; Furmanek P.,; Diez M (2014). Complex Convective Thermal Fluxes and Vorticity Structure: Geophysical Research Abstracts Vol. 17, EGU2015-14773, 2015 - EGU General Assembly 2015. [8] Nicolleau, F.C.G.A.; Cambon, C.; Redondo, J.M.; Vassilicos, J.C.; Reeks, M.; Nowakowski, A.F. (Eds.) (2012). New Approaches in Modeling Multiphase Flows and Dispersion in Turbulence, Fractal Methods and Synthetic Turbulence: ERCOFTAC Series. [9] Redondo J. M.; Sanchez M. A.; and Cantalapiedra I. R. (1995). Turbulent Mechanisms in Stratified Flows, Dynamics of Atmospheres and Oceans, 23, 454-462. [10] Matulka A.; Redondo J.M.; and Carrillo A. (2008) Experiments in stratified and rotating decaying 2D flows. II Nuovo Cimento 31, 5

  19. Detección molecular del virus de la fiebre amarilla en muestras de suero de casos fatales humanos y en cerebros de ratón.

    Directory of Open Access Journals (Sweden)

    Jairo A. Méndez

    2003-06-01

    Full Text Available Hemos adaptado un método molecular basado en la técnica de transcripción reversa seguida de la reacción en cadena de la polimerasa (RT-PCR para diagnóstico alternativo de la infección por el virus de la fiebre amarilla. Se tomaron tres sueros liofilizados de casos fatales de fiebre amarilla y cuatro sueros frescos, de los cuales tres pertenecían a casos fatales de la enfermedad y el cuarto a un paciente sintomático con serología IgM positiva para fiebre amarilla; los sueros fueron tratados con Trizol-LS® para extraer el ARN viral que fue sometido a reacción de RT y posteriormente a PCR, para la cual se diseñaron dos parejas de iniciadores específicos de fiebre amarilla: iniciadores directos (sentido JM2104 (5´-CGTTGGGAGAGGAGATTC-3´ y JM2249 (5´-TTCTTCACTTCGGTTGGG-3´, e iniciadores inversos (antisentido JM2673 (5´- TCATCTGCCCTGCTTCTC-3´ y JM2751 (5´-CCTCTCTGGTAAACATTCT-3´. La aplicación de la técnica en tejidos se hizo en cerebros de ratón infectados con el virus amarílico, tratados con una solución de lisis antes de purificar el ARN. En geles de agarosa se observaron bandas únicas de amplificación del tamaño esperado (569 pb y 502 pb; todas las muestras fueron corroboradas con las dos parejas de iniciadores y en dos de las muestras de suero fresco los resultados positivos para fiebre amarilla fueron comprobados con estudio histopatológico. Este método de detección molecular permitió demostrar de manera rápida y eficiente la presencia del virus de la fiebre amarilla, hecho que tiene importantes implicaciones diagnósticas para este problema de salud pública.

  20. COPD is a systemic disease – the ex trapulmonary manifestations

    African Journals Online (AJOL)

    Peripheral skeletal muscle dysfunction is an established systemic feature of COPD.12 .... vitamin A status in chronic obstructive pulmonary disease patients and ... Kempainen RR, Savik K, Whelan TP, Dunitz JM, Herrington CS, Billings. JL.

  1. corrosion response of low carbon steel in tropical road mud

    African Journals Online (AJOL)

    Dr Obe

    Corrosion Mitigation efforts using readily available anti- corrosion coatings to protect low carbon steel test coupons against the ... The following protective coating devices were effective: ..... 2 West, J.M (1986): Basic Corrosion and Oxidation,.

  2. Custom Changing: Fundamental Change Required, HUD Tells Realtors

    Science.gov (United States)

    Peabody, Malcom E., Jr.

    1973-01-01

    Discusses the practice of real-estate agents of steering'' minority families to particular neighborhoods when buying homes, and the programs the Department of Housing and Urban Development have undertaken to eliminate that practice. (JM)

  3. Genetics Home Reference: congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency

    Science.gov (United States)

    ... Vilar D, Pombo M, Dominguez F, Williams EL, Cole TR, Kirk JM, Kaminsky E, Rumsby G, Arlt ... medicine? What is newborn screening? New Pages Lyme disease Fibromyalgia White-Sutton syndrome All New & Updated Pages ...

  4. Ilmumised ja mediteerimised / Bill Viola ; interv. Harry Liivrand

    Index Scriptorium Estoniae

    Viola, Bill

    1998-01-01

    Bill Viola videoretrospektiiv Stedelijk Museumis, Rijksmuseumis, New Metropolises jm. Amsterdamis 29. novembrini. H. Liivrand Bill Violast ja tema loomingust. B. Viola oma videokunstist praegu ja 25 aastat tagasi, mil tema alustas, mõjutustest loomingule.

  5. Environment minister faces no-confidence proceedings / Kimberly Kweder

    Index Scriptorium Estoniae

    Kweder, Kimberly

    2007-01-01

    Leedu opositsiooniparteid väljendasid umbusaldust keskkonnaminister Arunas Kundrotase vastu, saates talle arupärimise küsimused EL-i fondide jagamise, jäätmekäitluse, vee ja õhu kvaliteedi jm. kohta

  6. Wiiralt, Arrak ja Sander oksjonil

    Index Scriptorium Estoniae

    2005-01-01

    Kunstioksjonil "Meistritöö" Pärnus Ammende villas oksjonil Adamson-Ericu "Kanal Montargis", Oskar Hoffmanni "Talumaja", Wiiralti töid, Jüri Arraku kaks natüürmorti, Mart Sanderi "South Bank Lion" jm

  7. Mintuleasa tänavas : lugu K.-st ehk kohtade kehastumisest ja kultuurilisest kapitalist / Indrek Peil

    Index Scriptorium Estoniae

    Peil, Indrek, 1973-

    2005-01-01

    Kehastunud ruumilistest suhetest linnas, vanade tööstushoonete taaskasutamisest, Tallinna tselluloosivabrikust, kultuurivabrikust, Raivo Kotovi ja Andrus Kõresaare Tallinna tselluloosivabriku otsa projekteeritavast pealeehitusest (elu- ja ärihoone Fahle Maja, KOKO Arhitektuuristuudio, 2004-2005) jm.

  8. Recommended Format for the Periodic Table of the Elements.

    Science.gov (United States)

    Loening, K. L.

    1984-01-01

    Presents a new, recommended format for the periodic table which does not use the letters A and B to designate subgroups of elements. Also describes events leading to the adoption of this recommendation. (JM)

  9. Volume 10 No. 11 November 2010 4340 SOIL MICROBE ...

    African Journals Online (AJOL)

    user

    2010-11-11

    Nov 11, 2010 ... SOIL MICROBE MEDIATED ZINC UPTAKE IN SOY BEAN: A REVIEW. Jefwa JM. 1* .... Porg, lipid Plp, high-energetic~P, sugar. Psuc and .... encouragement to prepare this presentation. ... Enviroquest Ltd Ontario, Canada.

  10. Konksu otsas graafiline disainer Jan Tomson / intervjueerinud Tanel Veenre

    Index Scriptorium Estoniae

    Tomson, Jan

    2009-01-01

    Jan Tomson endast, oma loomingust, rulasõidust, muusikategemisest, ajakirjast "Sahtel", igapäevadisainist jm. Jan Tomson on teinud plakateid, plaadikujundusi, logosid, grafitit, disaininud Kumu täpilise bussi ja optilise mustriga trammi ning muud

  11. Ruumieelikutest kogukonnaeelikuteni = From proto-spaces to proto-communities / Eik Hermann

    Index Scriptorium Estoniae

    Hermann, Eik

    2012-01-01

    Ärgitavast ruumist. Ärgitava ruumi ja ärksa kogukonna vastastiktekkimisest. Ärgitavast ruumist avaliku linnaruumi kontekstis. Linnalistest sekkumistest: sodimine, installatiivsete väikevormide loomine jm. Üllatusruumide spektrist: vasturuum, etendusruum, mänguruum

  12. Survival and photoreactivability of ultraviolet-irradiated cultured fish cells (CAF-MM1)

    International Nuclear Information System (INIS)

    Mano, Y.; Mitani, H.; Etoh, H.; Egami, N.

    1980-01-01

    The sensitivity to ultraviolet light (uv) and photoreactivating ability of cultured fish clone cells (CAF-MM1) were investigated. Dose-survival relationship curves were obtained using the colony-forming technique at various postirradiation temperatures (33, 26, and 20 0 C). At 26 0 C the values of D 0 , D/sub q/, and the extrapolation number (n) were 1.74 J/m 2 , 2.62 J/m 2 , and 4.5, respectively; no marked differences in these values were found among different temperatures. Visible light illumination after uv irradiation produced a marked increase in survival. No photoreactivation effects were observed beyond about 30 h. Caffeine increased uv sensitivity of the CAF-MM1 cells, and from the results it is suggested that the cells have some caffeine-sensitive dark repair mechanisms

  13. Zellweger : kusagil on ikka üks suurem plaan / Christoph Zellweger ; interv. K. M.

    Index Scriptorium Estoniae

    Zellweger, Christoph

    2002-01-01

    Šveitsi-austria päritolu, praegu Inglismaal elav ja töötav ehtekunstnik Christoph Zellweger endast, oma loomingust, mida tema tööd kajastavad, ehtekunsti väljavaadetest, implantaatidest, eesti ehetest jm.

  14. Genetics Home Reference: Partington syndrome

    Science.gov (United States)

    ... Demeer B, Poirier K, Biancalana V, Pinoit JM, Julia S, Chelly J, Devys D, Mandel JL. ARX polyalanine ... The phenotypic spectrum of ARX mutations. Dev Med Child Neurol. 2005 Feb;47(2):133-7. Review. ...

  15. Effect of streaming by gender on student achievement in ...

    African Journals Online (AJOL)

    related differences in cerebral organization. In: Wilting MA 85 Patterson AC (eds). Sex related difference in cognitive functioning. New York: Academic Press. Changeiywo JM 2000. Students' images of science in Kenya: A comparison of gender.

  16. Priit Põldme tahab tõsta sisearhitektuuri mainet / Ell-Maaja Randküla

    Index Scriptorium Estoniae

    Randküla, Ell-Maaja, 1939-2016

    2004-01-01

    28. X 2004. a. Eesti Sisearhitektide Liidu esimeheks valitud Priit Põldmest ja tema loomingust. P. Põldme eesti sisearhitektuuri maine tõusust Eestis, minimalismist kodukujunduses, ESL-i tulevikuplaanidest jm. Krista Kodres P. Põldmest sisekujundajana. 4 ill

  17. Oleme alati inimese haavatavuse juures tagasi : mis on tänase ehte probleem? / Kadri Mälk

    Index Scriptorium Estoniae

    Mälk, Kadri, 1958-

    2002-01-01

    Ehtekunstnikest, ehtekunstiajakirjast Décidé, ehtekunsti arengust ning tagasiliikumisest vastupidavate materjalide ja vanade tehnikate juurde, ehte hingearsti rollist, eesti ehtekunstist jm. Ehtekunstnike - T. Veenre, G. Corvaja, P. Hirv, B. Metcalf, C. Kransen, R. Baines - kommentaarid.

  18. Maagiliste momentide mütoloogia : intervjuu Peter Cook'iga / Peter Cook ; interv. Vilen Künnapu

    Index Scriptorium Estoniae

    Cook, Peter

    2002-01-01

    5. Põhja- ja Baltimaade Arhitektuuritriennaalil esinenud inglise arhitekt P. Cook endast, oma loomingust, rühmitusest Archigram, mis pälvis 2002. a. RIBA (Royal Institute of British Architects) kuldmedali, Tallinnast jm. Kommenteerinud Triin Ojari

  19. Inside : küpse sisustaja oaas / Margit Aedla

    Index Scriptorium Estoniae

    Aedla, Margit, 1970-

    2008-01-01

    Tallinnas Lootsi tänaval asuvast sisustussalongist Inside ja seal pakutavast mööblist, valgustitest jm. Salong on sisustatud näidiskoduna ning mõeldud kogenumale ja jõukale sisustajale. Kommenteerib omanik Jana Tool

  20. Genetics Home Reference: 2-hydroxyglutaric aciduria

    Science.gov (United States)

    ... Ben-Omran T, Hoffmann GF, de Lonlay P, McDonald MT, Meberg A, Muntau AC, Nuoffer JM, Parini ... 10 All Bulletins Features What is direct-to-consumer genetic testing? What are genome editing and CRISPR- ...

  1. Cell viability and repair systems in mammal cells

    International Nuclear Information System (INIS)

    Menck, C.F.; Meneghini, R.

    1982-01-01

    Synchronized cell cultures of mice are irradiated with 4,0J/m 2 ultraviolet light at different times. The possible mechanisms involved in the recuperation of the cellular survival observed, are discussed. (M.A.) [pt

  2. A Contrastive Haitian Creole-English Checklist

    Science.gov (United States)

    Hall, R. M. R.; Hall, Beatrice L.

    1971-01-01

    Teachers must recognize that, according to every reliable linguistic survey of the French-speaking Caribbean area, all social classes, except recent European immigrants, speak French Carribbean Creole, not Standard French, as their first language. (JM)

  3. Adaptive Education.

    Science.gov (United States)

    Anderson, Lorin W.

    1979-01-01

    Schools have devised several ways to adapt instruction to a wide variety of student abilities and needs. Judged by criteria for what adaptive education should be, most learning for mastery programs look good. (Author/JM)

  4. Optimismi viljad = The Fruits of Optimism / Tõnu Laigu

    Index Scriptorium Estoniae

    Laigu, Tõnu

    2005-01-01

    Mida võtta ette 1950-1990 massilise tüüpelamuehituse käigus Euroopas ja Eestis ehitatud elurajoonidega, mis ei vasta keskkonna, halva ehituskvaliteedi jm. põhjuste tõttu enam vajadustele. Bibliograafia lk. 55

  5. Genetics Home Reference: FG syndrome

    Science.gov (United States)

    ... MJ, Hoo JJ, Jones KL, McKeown C, Moeschler JB, Raymond FL, Rogers RC, Schwartz CE, Battaglia A, ... E, Huddleston L, Clark RD, Jones KL, Moeschler JB, Opitz JM, Morford J, Simensen R, Rogers RC, ...

  6. Manifestically correct / Harry Liivrand

    Index Scriptorium Estoniae

    Liivrand, Harry, 1961-

    2000-01-01

    Euroopa kaasaegse kunsti biennaal Manifesta 3 Ljubljanas deviisi all "Piirijoone sündroom. Kaitsmise energiad". Eestit esindab Ene-Liis Semper videoinstallatsiooniga "FF / Rew". Aleksandr Breneri aktsioonist. Bosnia-Hersegoviina kunstniku Sejla Kamerici tööst jm

  7. Eigenfunction statistics for Anderson model with Hölder continuous ...

    Indian Academy of Sciences (India)

    The Institute of Mathematical Sciences, Taramani, Chennai 600 113, India ... Anderson model; Hölder continuous measure; Poisson statistics. ...... [4] Combes J-M, Hislop P D and Klopp F, An optimal Wegner estimate and its application to.

  8. Disease: H00430 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 8328989 (gene, description) ... AUTHORS ... Kaplan FS, Le Merrer M, Glaser DL, Pignol...i IH, Connor JM, Delai P, Glaser DL, LeMerrer M, Morhart R, Rogers JG, Smith R, Triffitt JT, Urtizberea JA,

  9. Diagnosis and treatment of diabetic ketoacidosis

    African Journals Online (AJOL)

    of death, which can be prevented by early and effective management. All physicians ..... mechanisms and management strategies in sub-Saharan Africa: A review. ... Sacks DB, Burns DE, Goldstein DE, Maclaren NK, McDonald JM, Parrott M.

  10. Models of Educational Attainment: A Theoretical and Methodological Critique

    Science.gov (United States)

    Byrne, D. S.; And Others

    1973-01-01

    Uses cluster analysis techniques to show that egalitarian policies in secondary education coupled with high financial inputs have measurable payoffs in higher attainment rates, based on Max Weber's notion of power'' within a community. (Author/JM)

  11. 'Seal, kus oleme meie, on muuseum!' ; Eva ja Adele Helsingis / interv. Heie Treier

    Index Scriptorium Estoniae

    1998-01-01

    Elavad skulptuurid Saksamaalt Eva ja Adele etendasid moodsa kunsti muuseumi Kiasma avamisel performance'it 'Seal, kus oleme meie, on muuseum'. Intervjuu kunstnikega. Kunstnikepaarist, nende eesmärgist, millistes maades võetakse neid kergemini vastu, Kiasmast jm

  12. Eramu interjöör Aaviku elamurajoonis Harjumaal = Interior of a private home, Aaviku / Epp Lankots

    Index Scriptorium Estoniae

    Lankots, Epp, 1976-

    2005-01-01

    Aaviku asumi tüüpmaja sisekujunduse kontseptsioon on rajatud vineeri erinevatele kasutusviisidele. Vineeriga on kaetud seinad, laed, vineerist on köögilaud ja selle jalad jm. Sisearhitekt Tiiu Truus. 5 värv. ill

  13. Klassikaküsimus

    Index Scriptorium Estoniae

    2000-01-01

    Sisearhitektid ja mööblikaupmehed peavad 20. sajandi silmapaistvamaks saavutuseks A. Aalto painutatud vineerist mööblit, P. Starcki loomingut, inglise klubimööblit, Eileen Gray mööblit jm. 9 ill

  14. Statistical variations in chloride diffusion in concrete bridges

    Czech Academy of Sciences Publication Activity Database

    Tikalsky, P.; Pustka, D.; Marek, Pavel

    2005-01-01

    Roč. 102, č. 3 (2005), s. 481-486 ISSN 0889-3241 Institutional research plan: CEZ:AV0Z20710524 Keywords : bridge deck * corrosion * durability Subject RIV: JM - Building Engineering Impact factor: 0.544, year: 2005

  15. Unmodified electroconvulsive therapy

    African Journals Online (AJOL)

    Administrator

    acute phase reactants (C-reactive protein, á-2-macroglobulin, ceruloplasmin, factor B, C-4 ..... College of Physicians. [Oral](Personal Communication, 28 November 2008) ... Walter G, McDonald A, Rey JM, Rosen A. Medical student knowledge ...

  16. Subcutaneous Implantable Cardioverter-Defibrillator

    Science.gov (United States)

    ... discriminator functions and lacks antitachycardia pacing. Expanded Programmability Programming that allows lower shock energies and the ability ... 2014 American Heart Association, Inc. References 1. ↵ Weiss R , Knight BP , Gold MR , Leon AR , Herre JM , ...

  17. Inhibitors

    Science.gov (United States)

    ... JM, and the Hemophilia Inhibitor Research Study Investigators. Validation of Nijmegen-Bethesda assay modifications to allow inhibitor ... webinars on blood disorders Language: English (US) Español (Spanish) File Formats Help: How do I view different ...

  18. Water: Too Precious to Waste.

    Science.gov (United States)

    National Geographic World, 1983

    1983-01-01

    Provides background information on many topics related to water. These include the water cycle, groundwater, fresh water, chemical wastes, water purification, river pollution, acid rain, and water conservation. Information is presented at an elementary level. (JM)

  19. A SIMPLE SPECTROPHOTOMETRIC DETERMINATION OF TRACE ...

    African Journals Online (AJOL)

    a

    proposed method is based on the reaction of vanadium(V) with potassium iodide in ... coupled plasma atomic emission spectrometry [6], mass spectrometry [7] and atomic ..... Green, J.M. A Practical Guide to Analytical Method Validation, Anal.

  20. The effect of thrombolytic therapy on QT dispersion in acute ...

    African Journals Online (AJOL)

    2013-07-02

    Jul 2, 2013 ... intraventricular conduction defect or atrial fibrillation were excluded from the study. .... detection and their benign characteristics. In some series including .... Glancy JM, Garratt CJ, Woods KL, de Bono DP. QT dispersion and ...

  1. Hepatitis

    Science.gov (United States)

    ... Gastrointestinal and Liver Disease. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 90. Pawlotsky J-M. Chronic ... eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 149. Sjogren MH, Bassett JT. ...

  2. Pekingi kunstielu / Reet Varblane

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    2005-01-01

    Peking nüüdiskunsti keskusena. Hiina rahvuskunsti muuseumist (NAMOC), kultuurikeskusest Factory 798, Punase Värava galeriist (juhataja Brian Wallace), rahvusvahelisest kunstilaagrist BIAC (Beijing International Art Camp), East End Art Village'ist, kaasaja kunsti instituudist jm.

  3. Fatigue Properties of Orthotropic Decks on Railway Bridges

    Czech Academy of Sciences Publication Activity Database

    Frýba, Ladislav; Gajdoš, Lubomír

    1999-01-01

    Roč. 21, č. 7 (1999), s. 639-652 ISSN 0141-0296 Grant - others:XX(CZ) ERRI D 191 Keywords : railway bridges * orthotropic decks * fatigue Subject RIV: JM - Building Engineering Impact factor: 0.364, year: 1999

  4. Sisemine vabadus määrab identiteedi / Marie-Jo LaFontaine ; interv. Reet Varblane

    Index Scriptorium Estoniae

    LaFontaine, Marie-Jo

    2001-01-01

    Intervjuu belgia kunstniku Marie-Jo LaFontaine'iga 25. VII Rakveres. KanaNaha raames eksponeeritud M.-J. LaFontaine'i näitusest "Identiteedi ruum", tema fotodest lastest, kunstiturust Eestis ja Belgias, Belgia pankade kunstikogudest jm.

  5. Fotokuu näituse kuraator Adam Budak on ühendanud filmi, arhitektuuri ja filosoofia / Adam Budak ; intervjueerinud Andreas Sepp

    Index Scriptorium Estoniae

    Budak, Adam, 1966-

    2011-01-01

    Kumu Kunstimuuseumis 8. jaanuarini 2012 avatud rahvusvahelise kaamerakunsti näituse "Teisele poole" kuraator kaasaegse kunsti kuraatori tööst, näituse "Teisele poole" kureerimise lähtekohtadest, varasematest kokkupuudetest Tallinnaga, endast, kolimisest Ameerikasse jm.

  6. V poiskah garmonii / Rafael Danieljants ; interv. Tamara Unanova

    Index Scriptorium Estoniae

    Danieljants, Rafael

    2000-01-01

    Armeenia päritolu skulptor Rafael Danieljants (EKA, 1984) oma töödest, õpetajatööst Maardu kunstikoolis jm. Viimane tema tööde näitus oli Armeenia kultuurikeskuses Tallinnas : eksponeeriti armeeniateemalisi skulptuure

  7. Ještě k Ještědu

    Czech Academy of Sciences Publication Activity Database

    Fischer, Ondřej

    2008-01-01

    Roč. 2, č. 8 (2008), s. 18-20 ISSN 1802-2030 Institutional research plan: CEZ:AV0Z20710524 Keywords : television tower * rigidity of antenna structures * damping of wind-excitd vibrations Subject RIV: JM - Building Engineering

  8. Ocular Axial Length Measurement Among Normal Adults Using ...

    African Journals Online (AJOL)

    2017-07-26

    Jul 26, 2017 ... eye is the AL and report from previous studies suggest that in an adult, the average ... 2017 Nigerian Journal of Ophthalmology | Published by Wolters Kluwer - Medknow ..... Parel JM, Gelender H, Trefers WF, Norton EW.

  9. Qualitative Data Analysis Strategies

    OpenAIRE

    Greaves, Kristoffer

    2014-01-01

    A set of concept maps for qualitative data analysis strategies, inspired by Corbin, JM & Strauss, AL 2008, Basics of qualitative research: Techniques and procedures for developing grounded theory, 3rd edn, Sage Publications, Inc, Thousand Oaks, California.

  10. Meediaajastu arhitektid = Architects in the Media Era / Pedro Gadanho ; interv. Tõnis Kimmel, Kaur Stöör

    Index Scriptorium Estoniae

    Gadanho, Pedro

    2002-01-01

    Intervjuu 2002. a. märtsis Tallinnas Rotermanni soolalaos eksponeeritud briti arhitektuurinäituse "Space Imvaders" kuraatori P. Gadanhoga. Arhitekti tööst ja rollist kaasaegsetes linlikes protsessides, lühidalt Eesti büroodest jm

  11. How Nan Keohane Is Changing Duke: With a Focus on Building Consensus, She Is Transforming the University.

    Science.gov (United States)

    Basinger, Julianne

    2000-01-01

    Nannerl Keohane became president of Duke University in 1993, one of the first women to lead a top research university. This article details some of the changes that have taken place during her tenure as president. (JM)

  12. Disease: H00082 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 0:397-409 (2004) DOI:10.1046/j.1365-2265.2004.01978.x ... PMID:12734493 (gene, env_factor, marker, autoantigen) ... AUTHORS ... Ai J, Leonha...rdt JM, Heymann WR. ... TITLE ... Autoimmune thyroid diseases: etiology, pathogenesis

  13. Global Journal of Agricultural Sciences - Vol 10, No 1 (2011)

    African Journals Online (AJOL)

    Wild vertebrate pests activities on agricultural crops at Gashaka Gumti National Park, Nigeria · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. TF Ikpa, BI Dagba, JM Akusu, 33-37 ...

  14. West African Journal of Applied Ecology - Vol 25, No 1 (2017)

    African Journals Online (AJOL)

    The contribution of bank and surface sediments to fluvial sediment transport of the Pra River · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. J.M. Kusimi, 69-85 ...

  15. SOME QUANTUM CHEMICAL STUDY ON THE STRUCTURAL ...

    African Journals Online (AJOL)

    Preferred Customer

    unoccupied molecular orbital (LUMO) energy, HOMO-LUMO gap energy, RHF energy, some of important bond ..... Sobczak, J.M.; Glowiak, T.; Zio, J.J. Transition Met.Chem. ... Wiley-VCH: Velang GmbH, Weinheim (Germany); 2000. (b) Becke ...

  16. Inequality and Education

    Science.gov (United States)

    Lasch, Christopher

    1973-01-01

    Reviews a book by Christopher Jencks et al., examining a number of statistical correlations between income and schooling; and also books by Katz, Spring, and Greer respectively, examining the historical development of the American public school. (JM)

  17. Intrathecal Delivery of Ketorolac Loaded In Situ Gels for Prolonged ...

    African Journals Online (AJOL)

    ... parent drug calculated on the basis of drug contents; b Mean ± SEM, n = 6; c Change in .... Block JH and Beale JM, Eds, Wilson and Giswolds Text ... nano- hydroxyapatite/collagen/alginate hydrogels for osteochondral tissue engineering.

  18. ORiON - Vol 30, No 2 (2014)

    African Journals Online (AJOL)

    Efficient waste reduction algorithms based on alternative underestimates for the modied Wang method · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. JA Oberholzer, JM Hattingh, T Steyn, 73-83 ...

  19. Thalassemia intermedia: An overview

    African Journals Online (AJOL)

    Rabah M. Shawky

    2012-04-25

    Apr 25, 2012 ... abnormalities occur due to massive expansion of erythroid bone marrow activity ..... [3] Savage D, Wood NAP, Bidwell JL, Fitches A, Old JM, Hui KM. Detection of b-thalassemia mutations using DNA heteroduplex generator ...

  20. ISSN 2073 East Cent. Afr. j. surg.

    African Journals Online (AJOL)

    DELL

    2009-02-27

    Feb 27, 2009 ... Bladder Tumours at Tikur Anbessa Hospital in Ethiopia. ... The most common presenting symptoms were hematuria in 89(91.8%). cystoscopy ..... West DA, Cummings JM, Longo WE, et al; Role of chronic catheterization in the.

  1. A Sequence of Sorting Strategies.

    Science.gov (United States)

    Duncan, David R.; Litwiller, Bonnie H.

    1984-01-01

    Describes eight increasingly sophisticated and efficient sorting algorithms including linear insertion, binary insertion, shellsort, bubble exchange, shakersort, quick sort, straight selection, and tree selection. Provides challenges for the reader and the student to program these efficiently. (JM)

  2. Although the effects of climate change on crops are well known ...

    African Journals Online (AJOL)

    tina

    Climate change and livestock production: A review with emphasis on Africa. J.M. Rust. # .... which African farmers adapted livestock management to the range of climates across the continent. A ..... In: Handbook of methods for climate change ...

  3. Revue d'Information Scientifique et Technique - Vol 5, No 1 (1995)

    African Journals Online (AJOL)

    COCACOM : environnement de développement d'applications coopérantes et multimédia · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. J-M. Inglebert, L Courtrai, S Sadou ...

  4. Stigma and Deviant Careers in Schools

    Science.gov (United States)

    Fisher, Sethard

    1972-01-01

    Reports research attempting to test the labelling theory" approach to deviance by comparing a publically deviant" group of seventh, eighth, and ninth grade pupils with a similar group of pupils with no known history of delinquency. (JM)

  5. Vannisalong Coral pakub kvaliteeti soodsa hinna eest

    Index Scriptorium Estoniae

    2007-01-01

    Tallinnas A. H. Tammsaare tee 116 ja Tartus Teguri 45 asuvas vannisalongis Coral pakutakse põhiliselt vanne ja saunu, kuid müügil on ka dušikabiinid, segistid, valamud, vannitoamööbel, basseinid jm

  6. Rifampicin and chloramphenicol effects on DNA replication in ultraviolet-damaged Escherichia coli B/r WP2 thy trp

    International Nuclear Information System (INIS)

    Doudney, C.O.

    1976-01-01

    The antibiotic rifampicin, which blocks specifically RNA synthesis, limited DNA replication in Escherichia coli strain B/r WP2 thy trp after an increase of about 50% when added to the incubation medium at the time of replication initiation after ultraviolet fluences of 20 J/m 2 or 25 J/m 2 . Chloramphenicol, which blocks protein synthesis, did not limit DNA replication when added at initiation or any time after. The prolonged lag in DNA replication caused by ultraviolet was not itself responsible for the rifampicin limitation. When a lag of 30 min was caused by starvation for thymine, DNA was synthesized after readdition of thymine to an increase of 100% or more in rifampicin-containing medium. When chloramphenicol was added to an ultraviolet-exposed culture, the limiting effect of rifampicin alone was suppressed. This effect held even with a higher fluence (32.5 J/m 2 ), after which the ability to make DNA in the presence of rifampicin alone was slight. Maximum effect was obtained when the chloramphenicol was added to the ultraviolet-exposed, rifampicin-containing culture immediately before initiation of DNA replication. When rifampicin was present at a concentration of 150 μg/ml (2.2 x 10 -4 M), 3 μg/ml of chloramphenicol (9.2 x 10 -6 M) was as effective as 160 μg/ml (5.0 x 10 -4 M), thus eliminating the possibility that direct stoichiometric interaction of rifampicin and chloramphenicol molecules caused the effect

  7. Somatic mosaicism for DNA repair capacity in fibroblasts derived from a group A xeroderma pigmentosum patient

    International Nuclear Information System (INIS)

    Chang, H.R.; Ishizaki, K.; Sasaki, M.S.; Toguchida, J.; Kato, M.; Nakamura, Y.; Kawamura, S.; Moriguchi, T.; Ikenaga, M.

    1989-01-01

    A female Japanese xeroderma pigmentosum (XP) patient with severe skin lesions and various neurologic abnormalities was assigned to complementation group A by conventional cell fusion studies. Ultraviolet (UV)-irradiated skin fibroblasts showed a biphasic survival curve, as measured by colony-forming ability. The surviving fraction decreased rapidly up to 2 J/m2 of UV, with a steep slope of D(O) (mean lethal dose) = 0.95 J/m2. At much higher doses it decreased more slowly, with D(O) = 3.5 J/m2. To elucidate the cause of this unique survival response, we isolated a large number of independent clones from single colonies and measured their responses to UV. Of 81 clones analyzed, ten showed a marked resistance to killing by UV, which was only slightly more sensitive than normal cells, and these clones had a rate of unscheduled DNA synthesis (UDS) that was about 45% of normal cells. By contrast, the remaining 71 clones were extremely sensitive to UV, typical of XP group A strains, and had a UDS level 1%-3% of normals. Analysis of restriction fragment length polymorphism using seven polymorphic DNA probes indicated that the UV-resistant clones were derived from the same individual as the UV-sensitive clones. These results clearly demonstrate that this patient's fibroblast cells consist of two types with differing responses to UV, and provide direct evidence of somatic mosaicism for DNA repair capacity in an XP patient

  8. The effect of chronic low-dose UVB radiation on Langerhans cells, sunburn cells, urocanic acid isomers, contact hypersensitivity and serum immunoglobulins in mice

    International Nuclear Information System (INIS)

    El-Ghorr, A.A.; Norval, M.; Lappin, M.B.

    1995-01-01

    C3H mice were irradiated three times a week for up to 6 weeks with either 500 J/m 2 or 1000 J/m 2 broadband UVB (270-350 nm) or 3000 J/m 2 narrowband UVB (311-312 nm; TL01 source). Each dose was suberythemal to the mouse strain used. The number of Langerhans cells (LC) in the epidermis was reduced by over 50% after 2 weeks of irradiation with the UVB source and by 20% following TL01 irradiation. Continued irradiation for up to 6 weeks resulted in no further decrease in LC numbers in the case of the UVB source but a steady decline to 40% in the case of the TL01 source. Sunburn cells were detected following irradiation with both sources but the numbers were very low in comparison with acute exposure. Ultraviolet-B exposure resulted in doubling of the thickness of the epidermis throughout the 6 weeks of irradiation while TL01 exposure did not alter epidermal thickness. Conversion of trans- to cis-urocanic acid (UCA) was observed with both UVB and TL01 sources. The percentage of cis-UCA started to return to normal after 4 weeks of TL01 exposure despite continued irradiation. As observed following a single exposure, the contact hypersensitivity (CH) response was significantly reduced following 6 weeks of UVB irradiation but was unaffected by TL01 exposure, indicating no correlation between cis-UCA levels and CH response. (author)

  9. Nucleotide excision repair genes are expressed at low levels and are not detectably inducible in Caenorhabditis elegans somatic tissues, but their function is required for normal adult life after UVC exposure

    International Nuclear Information System (INIS)

    Boyd, Windy A.; Crocker, Tracey L.; Rodriguez, Ana M.; Leung, Maxwell C.K.; Wade Lehmann, D.; Freedman, Jonathan H.; Van Houten, Ben; Meyer, Joel N.

    2010-01-01

    We performed experiments to characterize the inducibility of nucleotide excision repair (NER) in Caenorhabditis elegans, and to examine global gene expression in NER-deficient and -proficient strains as well as germline vs. somatic tissues, with and without genotoxic stress. We also carried out experiments to elucidate the importance of NER in the adult life of C. elegans under genotoxin-stressed and control conditions. Adult lifespan was not detectably different between wild-type and NER-deficient xpa-1 nematodes under control conditions. However, exposure to 6 J/m 2 /day of ultraviolet C radiation (UVC) decreased lifespan in xpa-1 nematodes more than a dose of 100 J/m 2 /day in wild-type. Similar differential sensitivities were observed for adult size and feeding. Remarkably, global gene expression was nearly identical in young adult wild-type and xpa-1 nematodes, both in control conditions and 3 h after exposure to 50 J/m 2 UVC. Neither NER genes nor repair activity were detectably inducible in young adults that lacked germ cells and developing embryos (glp-1 strain). However, expression levels of dozens of NER and other DNA damage response genes were much (5-30-fold) lower in adults lacking germ cells and developing embryos, suggesting that somatic and post-mitotic cells have a much lower DNA repair ability. Finally, we describe a refinement of our DNA damage assay that allows damage measurement in single nematodes.

  10. Effects of UV-B radiation on tetraspores of Chondrus ocellatus Holm (Rhodophyta), and effects of red and blue light on repair of UV-B-induced damage

    Science.gov (United States)

    Ju, Qing; Xiao, Hui; Wang, You; Tang, Xuexi

    2015-05-01

    We evaluated the effects of red and blue light on the repair of UV-B radiation-induced damage in tetraspores of Chondrus ocellatus Holm. Tetraspores of C. ocellatus were treated with different UV-B radiation levels (0, 36, 72, 108, 144 and 180 J/m2), and thereafter subjected to PAR, darkness, or red or blue light during a 2-h repair stage, each day for 48 days. The diameters and cellular contents of cyclobutane pyrimidine dimmers (CPDs), chlorophyll a (Chl a), phycoerythrin, and UV-B-absorbing mycosporinelike amino acids (MAAs) contents of the tetraspores were determined. Our results show that low doses of UV-B radiation (36 and 72 J/m2) promoted the growth of C. ocellatus; however, increased UV-B radiation gradually reduced the C. ocellatus growth (greater than 72 J/m2). The MAAs (palythine and asterina-330) in C. ocellatus were detected and analyzed by LC/MS. Our results suggest that moderate red light could induce the growth of this alga in aquaculture. In addition, photorepair was inhibited by red light, so there may be some other DNA repair mechanism activated by red light. Blue light promoted the activity of DNA photolyase, greatly improving remediation efficiency. Red and blue lights were found to reduce the capacity of C. ocellatus to form MAAs. Therefore, PAR, red light, and blue light play different roles during the repair processes for damage induced by UV-B radiation.

  11. Experimental determination of the (vapor + liquid) equilibrium data of binary mixtures of fatty acids by differential scanning calorimetry

    International Nuclear Information System (INIS)

    Matricarde Falleiro, Rafael M.; Meirelles, Antonio J.A.; Kraehenbuehl, Maria A.

    2010-01-01

    (Vapor + liquid) equilibrium (VLE) data for three binary mixtures of saturated fatty acids were obtained by differential scanning calorimetry (DSC). However, changes in the calorimeter pressure cell and the use of hermetic pans with holes (φ = 250 mm) in the lids were necessary to make it possible to apply this analytical technique, obtaining accurate results with smaller samples and shorter operational times. The systems evaluated in this study were: myristic acid (C 14:0 ) + palmitic acid (C 16:0 ), myristic acid (C 14:0 ) + stearic acid (C 18:0 ), and palmitic acid (C 16:0 ) + stearic acid (C 18:0 ), all measured at 50 mm Hg and with mole fractions between 0.0 and 1.0 in relation to the most volatile component of each diagram. The fugacity coefficients for the components in the vapor phase were calculated using the Hayden and O'Connell method [J.G. Hayden, J.P. O'Connell, Ind. Eng. Chem. Process Design Develop. 14 (3) (1975) 209-216] and the activity coefficients for the liquid phase were correlated with the traditional g E models (NRTL [H. Renon, J.M. Prausnitz, Aiche J. 14 (1968) 135-144], UNIQUAC [D.S. Abrams, J.M. Prausnitz, Aiche J. 21 (1975) 116-128], and Wilson [J.M. Prausnitz, N.L. Linchtenthaler, E.G. Azevedo, Molecular Thermodynamics of Fluid-phase Equilibria, River-Prentice Hall, Upper Saddle, 1999]). The sets of parameters were then compared in order to determine which adjustments best represented the VLE.

  12. Bibliography: Artificial Intelligence.

    Science.gov (United States)

    Smith, Richard L.

    1986-01-01

    Annotates reference material on artificial intelligence, mostly at an introductory level, with applications to education and learning. Topics include: (1) programing languages; (2) expert systems; (3) language instruction; (4) tutoring systems; and (5) problem solving and reasoning. (JM)

  13. Browse Title Index

    African Journals Online (AJOL)

    2004), Equations for predicting the biomass of Acacia cyclops and Acacia saligna in the western and eastern Cape regions of South Africa: Part 1: tree-level models: scientific paper, Abstract. A Van Laar, JM Theron. Vol 201 ...

  14. Beyond Credentialism: The Future of Social Selection

    Science.gov (United States)

    Marien, Michael

    1971-01-01

    Social selection is analyzed within the context of the entire system of tests and certifications established and maintained by past society and serving certain functions for present society' three scenarios of the early 1980's are presented. (JM)

  15. Andres Noormets - olemuselt luuletaja, vormilt lavastaja / Andres Noormets ; intervjueerinud Tiiu Laks

    Index Scriptorium Estoniae

    Noormets, Andres, 1963-

    2010-01-01

    Andres Noormets endast, oma lavastustest, näitlemisest ja lavastamisest, elu mõttest, uue otsimisest oma teatritöödega, sellest, mis endiselt paelub teatris ja praegusi teatritegemisi enim mõjutab, ise kirjutamisest jm. Andres Noormetsa eluloolisi andmeid

  16. The Educational Implications of Serrano

    Science.gov (United States)

    Guthrie, James W.

    1973-01-01

    Describes the range of reforms that might result from the equal protection suits and assesses their educational consequences, good and bad, as well as assessing equal protection remedies in terms of their potential for education reform. (Author/JM)

  17. Staffing woes wound the Baltic tiger / Joel Alas

    Index Scriptorium Estoniae

    Alas, Joel

    2007-01-01

    Ilmunud ka: Eesti Ekspress, 26. apr. 2007, lk. A24-A25. Välismaised firmaomanikud probleemidest, mida tekitab nende ettevõtetele Eesti tööjõuturg - tõusvad palgad, madal produktiivsus, töölt puudumine jm

  18. Existence for stationary mean-field games with congestion and quadratic Hamiltonians

    KAUST Repository

    Gomes, Diogo A.; Mitake, Hiroyoshi

    2015-01-01

    Here, we investigate the existence of solutions to a stationary mean-field game model introduced by J.-M. Lasry and P.-L. Lions. This model features a quadratic Hamiltonian and congestion effects. The fundamental difficulty of potential singular

  19. A simple and efficient procedure to enhance artemisinin content in ...

    African Journals Online (AJOL)

    SERVER

    2007-06-18

    Jun 18, 2007 ... Full Length Research Paper. A simple .... The leaf material after the extraction was weighed (to measure the dry ... standard control in the measurement. ..... Ro DK, Paradise EM, Ouellet M, Fisher KJ, Newman KL, Ndungu JM,.

  20. Browse Title Index

    African Journals Online (AJOL)

    Items 151 - 200 of 323 ... Vol 19, No 1 (2015), Farmers' Perception of Climate Change and Coping ... AN Asadu, CL Egbujor, JM Chah, PI Ifejika ... Fertiliser on Farm Households' Risk Behaviour and Food Security in Ethiopia, Abstract PDF.

  1. Preparation and assessment of ketamine hydrogels for prolonged ...

    African Journals Online (AJOL)

    : 1596-5996 (print); ..... 15(11): 1249–1253. 16. Mahoney JM, Topical ketamine cream in the treatment of ... Transdermal drug delivery system of aceclofenac for rheumatoid arthritis and the effect of permeation enhancers: Invitro and in vivo ...

  2. Ettepanekud : Pärnu, 12. mai 2010 = Proposals : Pärnu, 12 May 2010

    Index Scriptorium Estoniae

    2011-01-01

    Pärnu linnafoorumil tehtud ettepanekud. Pika tänava eri pooltele jääva kahe linnakeskuse ruumiline ja funktsionaane sidumine, vanalinna ühendamine uue keskuse ja jõega, linnaliiklus, jõeäärse ala kujundamine jm.

  3. On optimal node and polynomial degree distribution in one-dimensional hp -FEM

    Czech Academy of Sciences Publication Activity Database

    Chleboun, J.; Šolín, Pavel

    2013-01-01

    Roč. 95, č. 1 (2013), s. 75-88 ISSN 1436-5057 R&D Projects: GA ČR GAP105/10/1682 Institutional support: RVO:61388998 Keywords : hp * boundary value problem * optimal mesh Subject RIV: JM - Building Engineering

  4. Disease: H00811 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available McMillin MJ, Below JE, Shively KM, Beck AE, Gildersleeve HI, Pinner J, Gogola GR, Hecht JT, Grange DK, Har...ris DJ, Earl DL, Jagadeesh S, Mehta SG, Robertson SP, Swanson JM, Faustman EM, Meff

  5. A Low-Cost, Precision Hydrometer for Classroom Use.

    Science.gov (United States)

    Murphy, Michael D.

    1983-01-01

    Describes a low cost hydrometer which can be assembled by students using stock laboratory items with a total retail cost of 17 cents. Includes list of required materials (with supplies) and experimental results on the instrument's accuracy. (JM)

  6. Kaarma Bold Italic / Tõnu Kaalep

    Index Scriptorium Estoniae

    Kaalep, Tõnu, 1966-

    2000-01-01

    Raamatukujundajast Jüri Kaarmast ja tema loomingust. Kommenteerib abikaasa Eve Kask. J. Kaarma sellest, miks temast sai raamatukujundaja, oma parimatest õpetajatest (E. Kärmas, I. Paul), töömeetodist, loomingust, uue kirjatüübi konstrueerimisest jm

  7. Kaarma Bold Italic / Tõnu Kaalep

    Index Scriptorium Estoniae

    Kaalep, Tõnu, 1966-

    2011-01-01

    Raamatukujundajast Jüri Kaarmast ja tema loomingust. Kommenteerib abikaasa Eve Kask. J. Kaarma sellest, miks temast sai raamatukujundaja, oma parimatest õpetajatest (E. Kärmas, I. Paul), töömeetodist, loomingust, uue kirjatüübi konstrueerimisest jm

  8. Background of two characteristic features of shape memory phenomena

    Czech Academy of Sciences Publication Activity Database

    Kafka, Vratislav; Vokoun, David

    2006-01-01

    Roč. 17, č. 6 (2006), s. 511-520 ISSN 1045-389X Institutional research plan: CEZ:AV0Z20710524 Keywords : shape memory * moduli * threshold stress Subject RIV: JM - Building Engineering Impact factor: 1.276, year: 2006

  9. The Expanding Universe and the Large-Scale Geometry of Spacetime.

    Science.gov (United States)

    Shu, Frank

    1983-01-01

    Presents a condensed version of textbook account of cosmological theory and principles. Topics discussed include quasars, general and special relativity, relativistic cosmology, and the curvature of spacetime. Some philosophical assumptions necessary to the theory are also discussed. (JM)

  10. Disease: H01057 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available nv_factor) ... AUTHORS ... Rusnak JM, Lucey DR ... TITLE ... Clinical gnathostomiasis: case report and review of the English-language liter...ature. ... JOURNAL ... Clin Infect Dis 16:33-50 (1993) DOI:10.1093/clinids/16.1.33

  11. Hiina minimaastikud / Jaan Mettik

    Index Scriptorium Estoniae

    Mettik, Jaan

    2007-01-01

    Hiinlaste minimaastike kunstist pen jing (maastik potis). Tavaliselt jaotatakse pen jing kolmeks: puukujuline, maastikku imiteeriv ning vee ja maa oma. Minimaastikele võib lisada tillukesi pagoode, inimkujukesi jm. Soositud on ohtralt dekoreeritud potid. 7 värv. ill

  12. Affective Assessment Is Necessary and Possible.

    Science.gov (United States)

    Anderson, Lorin W.; Anderson, Jo Craig

    1982-01-01

    Presents information that teachers need when undertaking affective assessment: why such assessment should be done, what should be assessed, what instruments are available, how to determine the quality of the instrument, and how to interpret scores. (Author/JM)

  13. Meest sõnast, meeri sarvest! / Jürgen Rooste

    Index Scriptorium Estoniae

    Rooste, Jürgen, 1979-

    2006-01-01

    Tallinn saab 2011. a. Euroopa kultuuripealinnaks. Muutustest, mida autor usub Tallinnas toimuma hakkavat (Vabaduse väljakult kaob parkla, teatrid saavad juurdeehitused, peatatakse kõrghoonete ehitamine Pirita tee äärde, hoogustub kultuuritehase Polymer töö jm.)

  14. Zachary-Fort Lauderdale pipeline construction and conversion project: final supplement to final environmental impact statement. Docket No. CP74-192

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-05-01

    This Final Supplement to the Final Environmental Impact Statement (Final Supplement) evaluates the economic, engineering, and environmental aspects of newly developed alternatives to an abandonment/conversion project proposed by Florida Gas Transmission Company (Florida Gas). It also updates the staff's previous FEIS and studies revisions to the original proposal. Wherever possible, the staff has adopted portions of its previous FEIS in lieu of reprinting portions of that analysis which require no change. 60 references, 8 figures, 35 tables.

  15. Hold your horSSEs: controlling structure-selective endonucleases MUS81 and Yen1/GEN1.

    Science.gov (United States)

    Blanco, Miguel G; Matos, Joao

    2015-01-01

    Repair of DNA lesions through homologous recombination promotes the establishment of stable chromosomal interactions. Multiple helicases, topoisomerases and structure-selective endonucleases (SSEs) act upon recombining joint molecules (JMs) to disengage chromosomal connections and safeguard chromosome segregation. Recent studies on two conserved SSEs - MUS81 and Yen1/GEN1- uncovered multiple layers of regulation that operate to carefully tailor JM-processing according to specific cellular needs. Temporal restriction of SSE function imposes a hierarchy in pathway usage that ensures efficient JM-processing while minimizing reciprocal exchanges between the recombining DNAs. Whereas a conserved strategy of fine-tuning SSE functions exists in different model systems, the precise molecular mechanisms to implement it appear to be significantly different. Here, we summarize the current knowledge on the cellular switches that are in place to control MUS81 and Yen1/GEN1 functions.

  16. Defining Threshold Values of Encapsulant and Backsheet Adhesion for PV Module Reliability: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Bosco, Nicholas S [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Kurtz, Sarah [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Eafanti, Joshua [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Tracy, Jared [Stanford University; Dauskardt, Reinhold [Stanford University

    2017-08-28

    The width-tapered cantilever beam method is used to quantify the debond energy (adhesion) of encapsulant and backsheet structures of 27 modules collected from the field. The collected population of modules contains both those that have remained in-tact and those with instances of either or both encapsulant and backsheet delamination. From this survey, initial threshold values (an adhesion value above which a module should remain intact throughout its lifetime) for encapsulant and backsheet interfaces are proposed. For encapsulants this value is about 60 J/m2 and for backsheets about 20 J/m2. It is expected that these values will continue to be refined and evolve as the width-tapered cantilever beam method becomes adopted by the PV industry, and that they may aid in the future improvement of accelerated lifetime tests and the development of new, low-cost materials.

  17. Intrinsic thermoluminescence of NaCl:Tl in UV dosimetry

    International Nuclear Information System (INIS)

    Barghare, S.P.; Joshi, R.V.; Joshi, T.R.; Kathuria, S.P.

    1982-01-01

    NaCl:Tl(T) phosphor is found to have high intrinsic thermoluminescence (TL) sensitivity to 253.7 nm UV-radiation. The dosimetric glow peak II grows sublinearly with increase in UV dose in the range 10 3 to 10 6 JM -2 . The other requirements of an efficient dosimeter material such as high storage stability, matching of the spectral response of detector tube and TL-emission from phosphor, reproducibility, desirable size and shape, easy availability in powder, pellet and crystal forms at cheaper rates, and repeated re-usability of the same phosphor without much difficulty, etc., are additional factors which strengthen the claim of NaCl:Tl(T) phosphor as UV dosimetric material. It is proposed that present NaCl:Tl(T) material is suitable TL-phosphor for UV dosimetry in the range 10 3 to 10 6 JM -2 . (author)

  18. Quantitative measurement of ultraviolet-induced damage in cellular DNA by an enzyme immunodot assay

    International Nuclear Information System (INIS)

    Wakizaka, A.; Nishizawa, Y.; Aiba, N.; Okuhara, E.; Takahashi, S.

    1989-01-01

    A simple enzyme immunoassay procedure was developed for the quantitative determination of 254-nm uv-induced DNA damage in cells. With the use of specific antibodies to uv-irradiated DNA and horseradish peroxidase-conjugated antibody to rabbit IgG, the extent of damaged DNA in uv-irradiated rat spleen mononuclear cells was quantitatively measurable. Through the use of this method, the amount of damaged DNA present in 2 X 10(5) cells irradiated at a dose of 75 J/m2 was estimated to be 7 ng equivalents of the standard uv-irradiated DNA. In addition, when the cells, irradiated at 750 J/m2, were incubated for 1 h, the antigenic activity of DNA decreased by 40%, suggesting that a repair of the damaged sites in DNA had proceeded to some extent in the cells

  19. Sequential plasma activation methods for hydrophilic direct bonding at sub-200 °C

    Science.gov (United States)

    He, Ran; Yamauchi, Akira; Suga, Tadatomo

    2018-02-01

    We present our newly developed sequential plasma activation methods for hydrophilic direct bonding of silica glasses and thermally grown SiO2 films. N2 plasma was employed to introduce a metastable oxynitride layer on wafer surfaces for the improvement of bond energy. By using either O2-plasma/N2-plasma/N-radical or N2-plasma/N-radical sequential activation, the quartz-quartz bond energy was increased from 2.7 J/m2 to close to the quartz bulk fracture energy that was estimated to be around 9.0 J/m2 after post-bonding annealing at 200 °C. The silicon bulklike bond energy between thermal SiO2 films was also obtained. We suggest that the improvement is attributable to surface modification such as N-related defect formation and asperity softening by the N2 plasma surface treatment.

  20. Sombreerodeta! : Argentina pealinn Eesti keskväljakul / Kristjan Arunurm

    Index Scriptorium Estoniae

    Arunurm, Kristjan

    2007-01-01

    Restoranist Buenos Aires Tallinnas Viru väljakul Foorumi keskuses. Sisekujundajad Janno Roos ja Andres Labi (Ruumilabor), nende kommentaarid. Interjööri aktsentideks on ligi pool tuhat suurt puumuna, erilise kujuga toolid jm. 6 värv. vaadet

  1. "Mitmesuguseid kuuldusi liigub..." : Teateid olukorra kohta Eestis 1943-1945 / koostaja Voldemar Kures

    Index Scriptorium Estoniae

    2015-01-01

    Soomes ja Rootsis põgenike intervjueerimise, Eestist tulnud kirjade, ajalehtede ja raadiosaadete jälgimise jm põhjal Voldemar Kurese poolt koostatud informatsioonikokkuvõtted Saksa okupatsiooni viimaste aastate, teise Nõukogude okupatsiooni algusaja olukorra ning eesti põgenike saatuse kohta

  2. Safety in the Chemical Laboratory--Chemical Management: A Method for Waste Reduction.

    Science.gov (United States)

    Pine, Stanley H.

    1984-01-01

    Discusses methods for reducing or eliminating waste disposal problems in the chemistry laboratory, considering both economic and environmental aspects of the problems. Proposes inventory control, shared use, solvent recycling, zero effluent, and various means of disposing of chemicals. (JM)

  3. LSD and Genetic Damage

    Science.gov (United States)

    Dishotsky, Norman I.; And Others

    1971-01-01

    Reviews studies of the effects of lysergic acid diethylamide (LSD) on man and other organisms. Concludes that pure LSD injected in moderate doses does not cause chromosome or detectable genetic damage and is not a teratogen or carcinogen. (JM)

  4. Lightning

    Science.gov (United States)

    Pampe, William R.

    1970-01-01

    Presents basic physical theory for movement of electric charges in clouds, earth, and air during production of lightning and thunder. Amount of electrical energy produced and heating effects during typical thunderstorms is described. Generalized safety practices are given. (JM)

  5. Effect of glucose infusion on endurance performance after beta-adrenoceptor blocker administration

    NARCIS (Netherlands)

    van Baak, M.A.; Mooij, J.M.

    1994-01-01

    Effect of glucose infusion on endurance performance after beta-adrenoceptor blocker administration. Van Baak MA, Mooij JM. Department of Human Biology, University of Limburg, Maastricht, The Netherlands. To investigate the effect of glucose (Glc) infusion on endurance performance after

  6. Efflux Pump‑Mediated Resistance in Chemotherapy

    African Journals Online (AJOL)

    to elucidate their structure and mechanisms of action so as to integrate the efflux pump mechanisms in the ... resistance. c. Alteration of the penicillin binding protein (PBP) in ..... Perloff MD, von Moltke LL, Fahey JM, Daily JP, Greenblat. DJ.

  7. Veneetsia arhitektuuribiennaalist, valgetest majadest ja Eesti koduarhitektuurist / Kalle Vellevoog ; intervjueerinud Margit Mutso

    Index Scriptorium Estoniae

    Vellevoog, Kalle, 1963-

    2010-01-01

    12. Venezia arhitektuuribiennaali Eesti väljapaneku "100 maja / houses" üks autoreid arhitekt Kalle Vellevooga Eesti ja lühidalt Soome väljapanekust, Eesti väljapanekutest eelmistel Venezia arhitektuuribiennaalidel, uutest elamurajoonidest Eestis, enda projekteeritud eramutest jm.

  8. A Simple Model of the Pulmonary Circulation for Hemodynamic Study and Examination.

    Science.gov (United States)

    Gaar, Kermit A., Jr.

    1983-01-01

    Describes a computer program allowing students to study such circulatory variables as venus return, cardiac output, mean circulatory filling pressure, resistance to venous return, and equilibrium point. Documentation for this Applesoft program (or diskette) is available from author. (JM)

  9. ORIGINAL ARTICLES

    African Journals Online (AJOL)

    sulfadoxine for fakiparum malaria. BMJ 1977; 1: 1626-1628. 5. De Souza JM, Sheth UK, De Oliveira RMG, et al. An open, randomised., phase ill clinical trial. Of mefloquine and of quinine plus sulfadoxine-pyrirnethamine in the treatment of.

  10. Jaak Prints: näitleja hirmud on üldinimlikud / Jaak Prints ; intervjueerinud Tiiu Laks

    Index Scriptorium Estoniae

    Prints, Jaak, 1981-

    2010-01-01

    Teatri NO99 näitleja Jaak Prints endast, näitlejaks olemisest, mõistest "mõtlev teater", koduteatrist, NO99 aktsioonist "Ühtne Eesti suurkogu", lavastamise soovist jm. Loetletud Jaak Printsi rollid ja tööd lavastajana

  11. role of heterogeneous astrocyte receptor expression in determining

    African Journals Online (AJOL)

    2018-02-28

    Feb 28, 2018 ... has been increasing (Denis et al, 1989; Lau and. Breteler, 2006). ... toxicity, the excess glutamate binds to N-Methyl-. D-aspartate ... absorption into the astrocyte (Lau and .... Heales JR, Lam AJ, Duncan AJ, Land JM. 2004.

  12. Investigation of a redox-sensitive predictive model of mouse embryonic stem cells differentiation using quantitative nuclease protection assays and glutathione redox status

    Science.gov (United States)

    Investigation of a redox-sensitive predictive model of mouse embryonic stem cell differentiation via quantitative nuclease protection assays and glutathione redox status Chandler KJ,Hansen JM, Knudsen T,and Hunter ES 1. U.S. Environmental Protection Agency, Research Triangl...

  13. Eramu Nõmmel = House in Nõmme / Piret Lindpere

    Index Scriptorium Estoniae

    Lindpere, Piret, 1963-

    2002-01-01

    Vabaduse puiesteel 2000. a. valminud eramu projekteeris arhitekt Jaan Ollik. Kujunduskonsultant Tiit Jürna kavandas CD-riiulid, lauad jm. Lihtsa musta maja väljapaistvaim osa on läbi kahe korruse ulatuv klaasist raamatukogu. 7 ill.: plaanid, vaated

  14. Vitamin D Supplementation for Prevention of Post-Traumatic Osteoarthritis: Evaluation in Animal and Clinical Models

    Science.gov (United States)

    2017-10-01

    Science of Variation Group (Wolf JM, SVG group member). Variation in recommendation for surgical treatment for compressive neuropathy. J Hand... Goldberg Arthritis Grant Animal Model of Vitamin D Supplementation for Prevention of Osteoarthritis This project evaluates the potentially preventive

  15. Instalaciones eléctricas en edificios de viviendas. Proyecto de un edificio.

    OpenAIRE

    Sánchez Rodríguez, Juan Manuel; Cárcel Carrasco, Francisco Javier

    2015-01-01

    Sánchez Rodríguez, JM.; Cárcel Carrasco, FJ. (2015). Instalaciones eléctricas en edificios de viviendas. Proyecto de un edificio. Area de Innovación y Desarrollo S.L. http://hdl.handle.net/10251/83665 Senia

  16. In Praise of the Little Phallus : On J.M. Coetzee's Contribution to Neophilologus

    NARCIS (Netherlands)

    Ruiter, F.

    2016-01-01

    ‘Erasmus’ Praise of Folly: Rivalry and Madness’ by J. M. Coetzee was published in 1992 in the January issue of Neophilologus. In hindsight, it can be said that it was an important text, both for Coetzee and for his commentators, who frequently refer to it. Not only does Coetzee present an

  17. 2018-03-28T03:12:24Z https://www.ajol.info/index.php/all/oai oai:ojs ...

    African Journals Online (AJOL)

    article/68491 2018-03-28T03:12:24Z wsa:ART Characterisation of the inorganic chemistry of surface waters in South Africa Huizenga, JM Inorganic water chemistry, inorganic chemistry index, South Africa, surface waters The main purpose of this ...

  18. Semen profiles of young men involved as bicycle taxi cyclists in ...

    African Journals Online (AJOL)

    006. 10. Vaamonde D, Da Silva-Grigolettob ME, García-Manso JM,. Cunha-Filho JS, Vaamonde-Lemos R. Sperm morphology normalcy is inversely correlated to cycling kilometers in elite triathletes . Rev Andal. Med Deporte. 2009;2(2):43-6. 11.

  19. Spectrum Recombination.

    Science.gov (United States)

    Greenslade, Thomas B., Jr.

    1984-01-01

    Describes several methods of executing lecture demonstrations involving the recombination of the spectrum. Groups the techniques into two general classes: bringing selected portions of the spectrum together using lenses or mirrors and blurring the colors by rapid movement or foreshortening. (JM)

  20. Small phosphatidate phosphatase (TtPAH2) of Tetrahymena ...

    Indian Academy of Sciences (India)

    Anoop Narayana Pillai

    2017-10-03

    Oct 3, 2017 ... There was no significant difference (indicated as 'ns') in the number of lipid droplets as analysed by Kruskal-Wallis test. (p \\0.01). .... and Goodman JM 2011 The yeast lipin orthologue Pah1p is ... gamma transcriptional activity.

  1. Durability analysis of a reinforced concrete member using probabilistic SBRA method

    Czech Academy of Sciences Publication Activity Database

    Pustka, D.; Marek, Pavel

    2007-01-01

    Roč. 2007, č. 7 (2007), s. 91-94 ISSN 1505-8425 R&D Projects: GA ČR(CZ) GA103/07/0557 Institutional research plan: CEZ:AV0Z20710524 Keywords : Reliability * Durability * SBRA method Subject RIV: JM - Building Engineering

  2. Television and Violence: Implications of the Surgeon General's Research Program

    Science.gov (United States)

    Murray, John P.

    1973-01-01

    Reports studies concerning: (a) the characteristics of television program content; (b) the characteristics of the audience--Who watches what? For how long? and, (c) the potential impact of televised violence on the attitudes, values, and behavior of the viewer. (Author/JM)

  3. Genetics Home Reference: neuroblastoma

    Science.gov (United States)

    ... 2008 Oct 16;455(7215):967-70. doi: 10.1038/nature07398. Citation on PubMed Maris JM. Recent advances ... 2008 Oct 16;455(7215):930-5. doi: 10.1038/nature07261. Epub 2008 Aug 24. Citation on PubMed ...

  4. Jaanus Rohumaa: "Every person should be a creator" / Jaanus Rohumaa ; intervjueerinud Maarja-Liis Arujärv

    Index Scriptorium Estoniae

    Rohumaa, Jaanus, 1969-

    2010-01-01

    SA Tallinn 2011 programmiosakonna juhataja Jaanus Rohumaa kultuuripealinna aasta mõttest, eesmärkidest ja programmist, ürituste kvaliteedist, eesti kultuurist ja rahvakultuurist, juurdepääsust kultuurile, loomekeskkonna parandamise võimalusest, Tallinna mitmetahulisusest ja rikkusest, koostööst jm.

  5. See võid sina olla. See võib olla sinu kloon. Sina võid olla kloon / Gregory Slick ; interv. Eero Epner

    Index Scriptorium Estoniae

    Slick, Gregory

    2003-01-01

    USA fotograaf G. Slick, kellel lõppes residentuur EKL külalisateljees, endast, oma loomingust, Eestist jm. G. Slick jätkas Eestis tööd seeriatega "Natural Histories" ja "Humans vs Space". Intervjuu on antud "Vikerraadio" saate "Kultuurikaja" jaoks

  6. African Peoples and Western Education

    Science.gov (United States)

    Onwauchi, P. Chike

    1972-01-01

    Argues that if the educational process is to be functionally relevant for the African peoples, it must be structured so as to maintain a dynamic pattern of continuity with the family and the cultural life patterns of the people. (Author/JM)

  7. Käsitsi tegemise võlu / David Jones ; intervjueerinud Kai Lobjakas

    Index Scriptorium Estoniae

    Jones, David, 1953-

    2010-01-01

    10. Kohila keraamikasümpoosionil osalenud briti keraamik ja teoreetik David Jones endast, rakutehnikast, huvist põletamisega seonduvate teemade vastu, Kohila sümpoosioni raames tehtust, keraamika õpetamisest Inglismaal, käsitöö ja keraamika positsioonist praegu ja tulevikus jm.

  8. Rüütel jäi kommunistinagi iseendaks / Arnold Rüütel ; intervjueerinud Hille Tänavsuu

    Index Scriptorium Estoniae

    Rüütel, Arnold, 1928-

    2001-01-01

    Arnold Rüütlile esitatud küsimused puudutavad tema minevikku, suhtumist noorte pahameeleavaldustesse pärast A. Rüütli valimist presidendiks, presidendi võimalusi mõjutada asjade käiku, president Lennart Merit, salaalkoholi leviku põhjusi jm. Parlamendisaadik

  9. The Cultural Basis for Our Environmental Crisis

    Science.gov (United States)

    Moncrief, Lewis W.

    1970-01-01

    Pollution is seen as prevalent throughout man's history and currently accentuated by democracy, industrialization, and capitalism. Faith in technology, lack of decisive response by social institutions, and absence of personal moral direction mediate against rapid solution of the environmental crisis. (JM)

  10. A Word to the Wise: Study That Franchise

    Science.gov (United States)

    Achtenburg, Ben

    1972-01-01

    Suggests that in deciding what should be written into the franchise of cable television and to whom it should be given, local groups can have their first and perhaps greatest influence over the way cable will affect their community. (JM)

  11. John Cale avaldas memuaarid

    Index Scriptorium Estoniae

    1999-01-01

    Rockbändi "The Velvet Underground" asutajaliige John Cale avaldas oma autobiograafia "What's Welsh for Zen?". Koos biograafiakirjanik Victor Bockrisiga kirjutatud teos räägib 60ndate lõpu kultuurielust New Yorgis, koostööst Andy Warholiga jm.

  12. 21. sajandi mammut / Martin Rästa ; intervjueerinud Tanel Veenre

    Index Scriptorium Estoniae

    Rästa, Martin, 1980-

    2010-01-01

    Kujundusgraafik Martin Rästaga (Mammut) tema tööst, loomingust, trendidest, graafilise disaini näituse eesmärkidest jm. Martin Rästa plakatite näitus "MMMT10" Tartu Y-galeriis 29. märtsist 10. aprillini 2010

  13. Ai Weiwei - 21. sajandi märter? / Tanel Veenre

    Index Scriptorium Estoniae

    Veenre, Tanel, 1977-

    2011-01-01

    Hiina kunstniku, inimõiguslase ja teisitimõtleja Ai Weiwei elust, õpingutest, loomingust ja tegevusest. Hiinas kunstniku tagakiusamisest, arreteerimisest, maksupettuses süüdistamisest jm. Kunstniku toetajatest. Inglise kunstileht Art Review valis Ai Weiwei 2011. a. kõige mõjuvõimsamaks kunstitegelaseks

  14. Aktsionäri kahju hüvitamise nõue aktsiaseltsi ja selle juhtorgani liikmete vastu / Margit Vutt

    Index Scriptorium Estoniae

    Vutt, Margit, 1968-

    2012-01-01

    Aktsionäri kahju hüvitamise nõudest rahalise jm kohustuse rikkumise korral. Aktsiaseltsi ja juhtorgani liikmete deliktiõiguslikust vastutusest. Juhtorgani liikmete vastutusest ühinemisel ja jagunemisel. Eesti ja Saksa õiguse ja kohtupraktika võrdlev analüüs

  15. Venemaa ja Valgevene hiiglaslikud spordikompleksid projekteeritakse Eestis / Signe Kalberg

    Index Scriptorium Estoniae

    Kalberg, Signe, 1959-

    2009-01-01

    Projekteerimisfirmast Ideab Project Eesti AS, firma suurprojektidest Valgevenes ja Venemaal. 2009. a. on sõlmitud lepingud energiasäästlike majade ehitamiseks Valgevenesse ja Sotši olümpiamängudeks laskesuusatamise kompleksi projekteerimiseks. Moskva kunstlumega suusalaskumisrajast, Norilski spordikompleksist jm.

  16. Kunst on vaimu avardumise üks keskseid koldeid / Peeter Maria Laurits ; interv. Laura Kuusk

    Index Scriptorium Estoniae

    Laurits, Peeter, 1962-

    2006-01-01

    Peeter Laurits oma loomingust, näitustest "Voolav labürint" (koostöö Katzi ja Hollandi Pavlov Medialabiga) SEB Ühispanga galeriis, "Meistriteoste varjus" (koos Laurentsiusega) Kadrioru Kunstimuuseumis, isikunäitusest "Vana labürint" ArtDepoos, autorikaitsest jm.

  17. Druhy pozemků a způsoby jejich využití

    Czech Academy of Sciences Publication Activity Database

    Kratěna, Jindřich

    2004-01-01

    Roč. 14, č. 1 (2004), s. 9-10 ISSN 1335-1133 R&D Projects: GA ČR GA103/97/S051 Institutional research plan: CEZ:AV0Z2071913 Keywords : covered area * garden * forest Subject RIV: JM - Building Engineering

  18. CLOUD-POINT EXTRACTION AND SPECTROPHOTOMETRIC ...

    African Journals Online (AJOL)

    Chem. Soc. Ethiop. 2017, 31(3), 373-382. ISSN 1011-3924. © 2017 Chemical Society of ..... Beale, J.M.; Block, J.H. Organic Medicinal and Pharmaceutical Chemistry, 12th ed.,. Lippincott Williams ... Talanta, 2016, 147, 510-515. 11. Habibi, B.

  19. Netiportaal teadmata kadunud kunstiteoste leidmiseks / Rael Artel

    Index Scriptorium Estoniae

    Artel, Rael, 1980-

    2003-01-01

    Ameerika Muuseumide Assotsiatsiooni loodud veebileht The Nazi-Era Provenance Internet Portal (www.nenip.org) pakub ülevaadet Euroopast 1932.-1946. a. natside tegevuse tulemusena kaduma läinud kunstiteostest (maalid, margi- ja mündikollektsioonid, mööbel jm.)

  20. Roheline disain / Villem Loigom

    Index Scriptorium Estoniae

    Loigom, Villem

    2007-01-01

    Ökodisainist. Mõiste eco design (green design) kasutusele võtnud austria disaineri Victor Papaneki (1927-1999) soovitusi. Näiteks toodud Ikea toolid ja 1995. a. Jan Drangeri disainitud täispuhutavad Rolig-toolid, 1958. a. Kaj Francki loodud Kartio klaasid jm

  1. Maarit Murka: oluline on olla igav / intervjueerinud Tanel Veenre

    Index Scriptorium Estoniae

    Murka, Maarit, 1981-

    2011-01-01

    Maalikunstnik Maarit Murka endast, oma loomingust, endise NSV Liidu vabariikides 2010. a. toimunud isikunäitustest, pikemalt näituse avamisest Minskis, rännakutest maailma pühapaikadesse jm. 2009. aastast õpib M. Murka Balti Filmi- ja Meediakooli stsenaristika magistrantuuris

  2. Raudtee uus tegevjuht lubab pikki ronge ja rohkem tonne / Earl Currie ; interv. Tuuli Koch

    Index Scriptorium Estoniae

    Currie, Earl

    2001-01-01

    Eesti Raudtee juhatuse esimees Earl Currie raudtee eelmise juhtkonna tegutsemisest, uue juhtkonna seisukohast läbirääkimistel ametiühingutega muutustest ER-i juhtimises, olulisematest investeeringutest jm. Earl Currie eluloost. Vt. samas "Rask näeb Savisaare avalduses kommunismi"

  3. Aiamängud vormi ja värviga / Anna-Liisa Unt ; interv. Victoria Parmas

    Index Scriptorium Estoniae

    Unt, Anna-Liisa, 1982-

    2006-01-01

    Eesti Maaülikoolis ja Rootsi Põllumajandusülikoolis maastikuarhitektuuri õppinud Anna-Liisa Unt (sünd. 1982) endast, oma aiakujundustest, tüüpilisest eestlase aiast tänapäeval jm. Anna-Liisa Undi tööde loetelu

  4. Relationships between hemoglobin A and spot glucose ...

    African Journals Online (AJOL)

    2011-05-12

    May 12, 2011 ... Nigerian Journal of Clinical Practice • Jan-Mar 2012 • Vol 15 • Issue 1. Original Article .... The Hospital Ethics and Research Committee approved .... Sacks DB, Bruns DE, Goldstein DE, Maclaren NK, McDonald JM, Parrott M.

  5. Case report

    African Journals Online (AJOL)

    ebutamanya

    French). 1984;30(3):177-81. PubMed |. Google Scholar. 12. Isla A, Paz JM, Sansivirini F, Zamora P, Garcia Grande A,. Fernandez A. Intramedullary spinal cord metastasis: a case report. J Neurosurg Sci. 2000 Jun; 44(2):99-101.

  6. Töösturi pojapoeg, kes mässab raha vastu / Kadri Paas

    Index Scriptorium Estoniae

    Paas, Kadri, 1982-

    2011-01-01

    Tänavused protestiaktsioonid Occupy Wall Street tegid tuntuks Kanadas elava tarbimisühiskonna kriitiku Kalle Lasni. Tallinnas sündinud Kalle Lasni elust, tegevusest, tema tennisistist isast Kristjan Lasnist. Kalle Lasn on ajakirja "Adbusters" asutaja, raamatu "Design Anarchy" autor jm.

  7. Kellele on vaja kunstnike vahetusprogramme? / Silvi Teesalu

    Index Scriptorium Estoniae

    Teesalu, Silvi

    2002-01-01

    Taani kunstielust: kunstimuuseumide juures tegutsevatest sõprade klubidest ning vabatahtlike toetajate ühendustest jm. Taani-Eesti graafikute vahetusprogrammidest (2000, 2001) ning ühisnäitustest (2001, 2002), Hjorringis ja Tallinnas töötanud graafikud. Vive Tolli isiknäitusest Taanis

  8. Anu Samarüütel-Long: sama kleiti võiks toota mitukümmend aastat / Anu Samarüütel-Long ; intervjueerinud Tanel Veenre

    Index Scriptorium Estoniae

    Samarüütel-Long, Anu, 1966-

    2010-01-01

    Anu Samarüütel-Long oma mais 2010 ilmunud reisikirjast "Minu London", Londonisse elama asumisest, õpingutest seal, Londonist kui loovlinnast, eesti disainist, soovist teha moedisaini, koostööst Montoniga, lihtsuse saavutamisest, eetilisest tootmisest, kunsti ja kaubanduse dialoogist jm.

  9. Expression of chimeric HCV peptide in transgenic tobacco plants ...

    African Journals Online (AJOL)

    Expression of chimeric HCV peptide in transgenic tobacco plants infected with recombinant alfalfa mosaic virus for development of a plant-derived vaccine against HCV. AK El Attar, AM Shamloul, AA Shalaby, BY Riad, A Saad, HM Mazyad, JM Keith ...

  10. Optimum growth rate of Belgian Blue double-muscled replacement ...

    African Journals Online (AJOL)

    Leo Fiems

    140. Forbes, J.M., 1995. Voluntary food intake and diet selection in farm animals. CAB International, Oxon, UK. Greenwood, P.L. & Café, L.M., 2007. Prenatal and pre-weaning growth and nutrition of cattle: long-term consequences for beef ...

  11. Eesti ajaloomuuseumi vanim kogu on...

    Index Scriptorium Estoniae

    2002-01-01

    19. XII avatud näitusega tähistab Ajaloomuuseum oma vanima kogu, Tallinna raeapteekri Johann Burchardi kollektsiooni "Mon Faible" ("Minu nõrkus") 200. sünnipäeva. Kogusse kuulub Tallinna timuka mõõk aastast 1525, etnograafilisi materjale jm.

  12. Case Report Gynaecomastia in two men on stable antiretroviral ...

    African Journals Online (AJOL)

    Jeremy D. Kratz1, Ahmad Y. El-Shazly2, Santos G. Mambuque2, Elpidio Demetria3, Peter ... Division of General Internal Medicine, University of California San Francisco, San .... Jover F, Cuadrado JM, Roig P, Rodriguez M, Andreu L, Merino J.

  13. Poska 28 elamust : kortermaja Tallinnas Kadriorus = About the Multi-Family Dwelling at Poska 28 : Apartment House in KadriorgTallinn / Tiit Trummal

    Index Scriptorium Estoniae

    Trummal, Tiit, 1954-

    2002-01-01

    Projekteerija: Alver Trummal Arhitektid. Autorid Tiit Trummal, Tarmo Laht, Ulla Mets. Konstruktsioonid: Aivar Lukk, Indrek Einloo. Üheksa korteriga elamul on avarad terrassid, rõdudele avanevad vannitoad jm. Projekt 2001, valmis 2002. 7 ill.: vaated, tüüpkorruse plaan

  14. MJZ VOL 37 NO 2.CDR

    African Journals Online (AJOL)

    MJZ

    350cells/cmm, although this requires further studies for validation. .... 0.001). In a multivariate logistic regression analysis that included all of the .... common habit in women in Zambia. Alcohol .... J.M, Dixon, ABC of Breast infection. BMJ. 1994 ...

  15. Liquid damper for suppressing horizontal and vertical motions of footbridges

    Czech Academy of Sciences Publication Activity Database

    Pirner, Miroš; Urushadze, Shota

    2004-01-01

    Roč. 49, č. 3 (2004), s. 295-328 ISSN 0001-7043 R&D Projects: GA AV ČR KSK1010104 Keywords : motion of liquid in container * container with two degrees of freedom * application on footbridges Subject RIV: JM - Building Engineering

  16. An Insider's View of the Teachers' Union and Women's Rights

    Science.gov (United States)

    Stern, Marjorie

    1973-01-01

    The author is chairman of the Women's Rights Committee of the American Federation of Teachers: she was invited to write this article in response to Women Teachers and Teacher Power,'' in the Urban Review,'' Vol. 6, No. 3. (Author/JM)

  17. Are Biology and Chemistry Out of Order?

    Science.gov (United States)

    Gaudin, Felix A.

    1984-01-01

    Discusses advantages and disadvantages of standard high school biology and chemistry course sequences. Relates these sequences to Piagetian developmental levels as well as to David Ausubel's cognitive theory. Suggests that the sequences be reexamined in light of issues considered. (JM)

  18. Toward an Understanding of Achievement-Related Conflicts in Women

    Science.gov (United States)

    Horner, Matina S.

    1972-01-01

    Identifies the motive to avoid success as an internal psychological representative of the dominant societal stereotype which views competence, independence, competition, and intellectual achievement as qualities basically inconsistent with femininity, even though positively related to masculinity and mental health. (Author/JM)

  19. Journal of Civil Engineering Research and Practice - Vol 6, No 1 ...

    African Journals Online (AJOL)

    A Prototype Gis-Based Road Pavement Information and Management System · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. JBK Kiema, JM Mwangi. http://dx.doi.org/10.4314/jcerp.v6i1.45192 ...

  20. ISSN 2073 ISSN 2073 9990 East Cent. Afr. J. s 9990 East Cent. Afr.

    African Journals Online (AJOL)

    Hp 630 Dual Core

    severe Mitral Valve Regurgitation and severe mixed Mitral Valve Disease. 1,2,3 ... syndrome which has been attributed to the loss of annulo ventricular continuity 4,5,6,7. ..... Rozich JD, Carabello BA, Usher BW, Kratz JM, Bell AE, Zile MR.

  1. Assessment of specific absorbed fractions for photons and electrons using average adult Japanese male phantom

    International Nuclear Information System (INIS)

    Manabe, Kentaro; Sato, Kaoru; Takahashi, Fumiaki

    2014-10-01

    The International Commission on Radiological Protection (ICRP) is revising dose coefficients, which are effective and equivalent doses per unit intake of radionuclides, based on the 2007 Recommendations. Specific absorbed fractions (SAFs) of voxel phantoms having standard physiques and organ masses (physical characteristics) of Caucasian are used for calculation of the new dose coefficients. SAFs depend on physical characteristics of a phantom used for assessment of the SAFs. Therefore, the SAFs and the dose coefficients developed by ICRP reflect physical characteristics of Caucasian. On the other hand, physiques of adult Japanese are generally smaller than those of adult Caucasian, and organ masses are also different from each other. Consequently, it is expected that SAFs and dose coefficients with physical characteristics of adult Japanese are different from those of ICRP. It is important to understand the influence of the differences in physical characteristics between both races on SAFs and dose coefficients when using the SAFs and dose coefficients of ICRP for radiation protection for Japanese. In order to evaluate internal doses considering the physical characteristics of adult Japanese, the Japan Atomic Energy Agency plans to develop a comprehensive data set of SAFs for photons, electrons, alpha particles and neutrons using average adult Japanese male and female phantoms (male: JM-103, female: JF-103). This report presents a data set of photon and electron SAFs for JM-103. JM-103 was incorporated into the general purpose radiation transport code, MCNPX 2.6.0, and the SAFs were calculated by the MCNPX 2.6.0 for 25 energies from 10 keV to 10 MeV and for combinations of 67 source regions and 41 target organs. Influences of differences in physical characteristics between adult Japanese and Caucasian on SAFs was also examined by comparison between the calculated SAFs in this study and the SAFs of the reference adult male phantom of ICRP. The photon and electron

  2. Bibliography of Testing and Evaluation Reference Material

    Science.gov (United States)

    1989-08-01

    G.W. Geber , and J.-M. Serre. "Semi-Automatic Implementation of Communica- tion Protocols." IEEE: Transactions on Software Engineering, 13/9 (Sep...GaudXX] Gault J.W.........................[(Scot84a], [Scot84b], EScot87J, (TrivSOJ Geber G.W

  3. 1. VI avati Haapsalus taas Evald Okase muuseum

    Index Scriptorium Estoniae

    2004-01-01

    Väljas on Evald Okase graafika ja joonistute uuendatud ekspositsioon, kunstniku 1930. aastate maalid. Programmis: fotonäitus "Väikeste majade Haapsalu", rahvusvaheline kuumklaasi workshop ja klaasinäitus "Maritima", kunsti suvekool, Eesti Maalikunstnike Liidu näitus "Ma olen olnud Haapsalus" jm.

  4. Kultuuripealinn Weimar

    Index Scriptorium Estoniae

    1999-01-01

    1. jaanuarist 1999 on järjekordseks Euroopa Liidu kultuuripealinnaks Weimar, kus on töötanud ka Cranachite kunstnikesuguvõsa, Walter Gropius. Tähtsamaid kollektiive, keda oodatakse esinema. Kultuuripealinna pidustuste raames tähistatakse Bauhausi asutamise 80. aastapäeva jm.

  5. African Journal of Aquatic Science - Vol 39, No 4 (2014)

    African Journals Online (AJOL)

    Water and habitat quality assessment in the Honi and Naro Moru rivers, Kenya, using benthic macroinvertebrate assemblages and qualitative habitat scores · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. JG Mbaka, CM M'Erimba, HK Thiongo, JM Mathooko.

  6. Communication, knowledge, social network and family planning ...

    African Journals Online (AJOL)

    AJRH Managing Editor

    Tanzania; 2Centre for International Development Initiatives Nijmegen (CIDIN) and ... demographic variables, social networks, knowledge and communication among the couples, whereby a stratified sample of 440 ..... FP method varies with urban- rural and regional ...... Pile JM and Simbakalia C. Tanzania Case Study: A.

  7. Nitrate contamination of drinking water: relationship with HPRT variant frequency in lymphocyte DNA and urinary excretion of N-nitrosamines

    NARCIS (Netherlands)

    van Maanen, J.M.S.; Welle, I.J.; Hageman, G.J.; Dallinga, J.W.; Mertens, P.L.; Kleinjans, J.C.S.

    1996-01-01

    Nitrate contamination of drinking water: relationship with HPRT variant frequency in lymphocyte DNA and urinary excretion of N-nitrosamines. van Maanen JM, Welle IJ, Hageman G, Dallinga JW, Mertens PL, Kleinjans JC. Department of Health Risk Analysis and Toxicology, University of Limburg,

  8. Managing Endometriosis in sub-Saharan Africa: Emerging Concepts ...

    African Journals Online (AJOL)

    AJRH Managing Editor

    . Obstet 1987; 25: 47 – 52. 8. Kyama CM, Mwenda JM, Machoki J, Mihalyi A,. Simsa P, Chai DC, D'Hoodge TM. Endometriosis in African women. Women's. Health 2007; 3(5): 629 – 635. 9. D' Hoodge TM. The challenge of Endometriosis: A.

  9. Et oksad võiksid kasvada, selleks on juuri vaja : eesti teatrikostüüm Natalie Meist tänapäevani / Kustav-Agu Püüman, Pille Jänes, Liina Unt...[jt.] ; interv. Reet Varblane

    Index Scriptorium Estoniae

    2000-01-01

    Eesti teatrikostüümist ja Natalie Mei rollist eesti kostüümikunstis. Kostüümikunstniku rollist ja haridusest, millest oleneb õige kostüümi loomine, trendid teatrikostüümis jm. L. Blumenfeldi kommentaar saadud e-posti teel.

  10. Toomas Vainola : Sojuz betona za beton! / Toomas Vainola

    Index Scriptorium Estoniae

    Vainola, Toomas, 1960-

    2004-01-01

    17. II asutasid 42 ehitusmaterjalitööstuse, ehitusettevõtete, arhitektide ja projekteerijate ning akadeemilise ringkonna esindajat Eesti Betooniühingu. Esimeheks valitud Toomas Vainola ühingu eesmärgist, liikmetest, betooni eelistest, 19. III toimuvast betoonipäevast, Aasta Betoonehitise konkursist jm.

  11. Festival 'Sünnisõnad' ئ igaühele midagi / Evi Arujärv

    Index Scriptorium Estoniae

    Arujärv, Evi, 1953-

    2000-01-01

    29. dets. 1999 - 1. jaan. 2000 toimunud festivalist "Sünnisõnad". Lühidalt ka nonstopfilmist 'Sajand arhitektuuri. Elavad pildid' (autor Karin Hallas), arhitektuurimuuseumi näitusest 'Eesti katedraalid'. 30. XII Nyyd Ensemble esitatud Gavin Bryarsi teosest 'Titanicu hukk' (Jaan Toomiku videod) jm.

  12. Iraani tipplavastaja: jõukas eliit teenib ideoloogiat / Homayun Ghanizadeh ; intervjueerinud Brigitta Davidjants

    Index Scriptorium Estoniae

    Ghanizadeh, Homayun

    2010-01-01

    Külalisetenduse "Caligula" (12. septembril Tartu draamafestivalil) lavastaja ja 11. augustil Tallinna Püha Katariina kirikus esietenduva "Antigone" ( Sophokles/Homayun Ghanizadeh) külalislavastaja Homayun Ghanizadeh räägib oma tööst, iraani teatrist, näitlejatest, teatri mainest jm.

  13. South African Medical Journal - Vol 96, No 12 (2006)

    African Journals Online (AJOL)

    Risk of malignancy in myasthenia gravis patients exposed to azathioprine therapy for a median period of 3 years · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. A Rawoot, F Little, JM Heckmann, 1249-1251 ...

  14. Minimalismist nostalgiaga / Varje Talivee, Piret Veigel

    Index Scriptorium Estoniae

    Talivee, Varje

    2004-01-01

    Heledate seintega avaras ruumis on värvitud üks sein šokolaadipruuniks, seinale on tõmmatud lai hele triip efektvärviga. Toas on kirju eebenipuu-spooniga laud, punasest siidist lühter, põrandal pärsia vaip jm. 12 ill

  15. Courseware Review.

    Science.gov (United States)

    Risley, John S.

    1984-01-01

    Evaluates two computer programs for Apple II which provide drill and practice in Newton's laws of motion and in work-energy relationships. Student performance is recorded on the diskette allowing the teacher to view the number of questions completed and percentage correct. (JM)

  16. Download this PDF file

    African Journals Online (AJOL)

    ÿþU s e r

    while nine patients (23.7%) had pin tract infection in the control group. There was a significantly lower ... duration of five days is expected to be incapable of preventing pin-tract .... Shapiro JM, Bond EL, Garman JK. 13. Hannan M; Juste RN; ...

  17. E-Duchamp / Maria-Kristiina Soomre

    Index Scriptorium Estoniae

    Soomre, Maria-Kristiina, 1978-

    2001-01-01

    Kolmas online-number Marcel Duchampi'i uurimisele keskendunud ajakirjast (http://www.toutfait.com) sisaldab Arthur Danto artikli "Marcel Duchamp and the End of Taste", Leif Erikksoni käsitluse Duchamp'i mõjust rootsi kunstile aastatel 1933-70, lõike monograafiatest jm.

  18. Paneelmajad pole kaardimajad / Karl Õiger

    Index Scriptorium Estoniae

    Õiger, Karl, 1933-

    1999-01-01

    Paneelmajade tehnilisest seisundist, ekspertiisi tegemisest, varisemisohust, vanade hoonete renoveerimisest ja ümberehitamisest, ehitamise kvaliteedist Eestis, nõukogude ajast ehituses, paneelelamutest ja munitsipaalelamufondist, mida tuleks paneelhoone juures jälgida jm. Artikli kirjutamise ajendiks oli Postimehe artikkel "Viitsütikuga majad" (18. VIII)

  19. Hommikuti peab sul olema suurim soov teatrisse tulla ja tööpäeva lõpus peab sul olema suurim soov koju minna / Rein Neimar ; intervjueerinud Triin Sinissaar

    Index Scriptorium Estoniae

    Neimar, Rein

    2011-01-01

    Intervjuu Tallinna Linnateatri asedirektori Rein Neimariga, kes tähistas 24. märtsil oma 60. sünnipäeva. Leningradi õppima minekust, teatritööst kui kollektiivsest tööst, teatriimest, sellest, mida teater on talle andnud jm.

  20. Mida arvate uuest ülikoolist Tallinnas? / Jaan-Mati Punning, Jüri Orn, Raivo Vetik, Jaan Õispuu ; vahendas Merike Määrits

    Index Scriptorium Estoniae

    2001-01-01

    Tallinna Pedagoogikaülikooli, Eesti Kunstiakadeemia ja Eesti Humanitaarinstituudi ühinemisest. Vastavad TPÜ ökoloogia instituudi professor J.-M. Punning, kasvatusteaduste teaduskonna professor J. Orn, TPÜ rahvusvaheliste sotsiaaluuringute instituudi professor R. Vetik ja läänemeresoome keelte professor J. Õispuu

  1. Kõrghoone "Tower" Tallinnas, Tartu mnt. ja Pääsukese tänava nurgal. Projekt, 1996. Arhitektid Vilen Künnapu ja Ain Padrik

    Index Scriptorium Estoniae

    1997-01-01

    32-korruselise torni neljal esimesel korrusel on kaubamaja, järgmisel viiel korrusel parkla, siis tehnilise korruse järel on 14 korrusel bürooruumid, seejärel viiel korrusel korterid, järgnevastel korrustel bürood, restoran, baar jm.

  2. Jalgsi, rongi või jalgrattaga? Käsu korras või kokkuleppel? / Gregory Ashworth ; intervjueerinud Liisa Pakosta

    Index Scriptorium Estoniae

    Ashworth, Gregory

    2011-01-01

    Intervjuu Groningeni ülikooli ruumiteaduste instituudi planeeringute osakonna professori Gregori Ashworthiga. Kultuuriturismist, linnaplaneerija võimalustest aidata kaasa turismile, turismi edendamise võimalustest Tallinnas, transpordipoliitikast, ühistranspordist, rongi- ja jalgrattaliiklusest, maa-alusest parkimisest, Kalamajast, planeeritava piirkonna elanike soovidega arvestamisest, avalike huvide kaitsest jm.

  3. 5 põhjust sukelduda Disainiöösse / Tanel Veenre

    Index Scriptorium Estoniae

    Veenre, Tanel, 1977-

    2009-01-01

    Kultuurifestivali Arts & Lights Disainiöö üritustest Tallinnas Rotermanni kvartalis 25.-27. sept. 2009. Näeb Reet Ausi kureeritud moevaatemängu "Kas oled kunagi mõelnud, miks elu on nagu on?", väljapanekut "Disaini Elevaator" Rotermanni elevaatoris, peetakse disainioksjon jm.

  4. Body weight and growth rate of South African Angora goat kids ...

    African Journals Online (AJOL)

    grethas

    E-mail: grethasn@nda.agric.za. Introduction ... production has been investigated (McGregor, 1998), but very little work has been done on the effect of different ..... Grégoire, R.J., Fahmy, M.H., Boucher, J.M., Tremblay, A. & Mercier, J., 1996.

  5. Comprehensive Environmental Assessment and U.S. EPA Nanomaterial Case Studies

    Science.gov (United States)

    These case studies are not completed risk assessments but are structured around an approach known as comprehensive environmental assessment (CEA), which combines a product life cycle framework with the risk assessment paradigm (Davis, J.M., J. Nanosci. Nanotech. 7:402-9, 2007). ...

  6. The Creative Brain.

    Science.gov (United States)

    Herrmann, Ned

    1982-01-01

    Outlines the differences between left-brain and right-brain functioning and between left-brain and right-brain dominant individuals, and concludes that creativity uses both halves of the brain. Discusses how both students and curriculum can become more "whole-brained." (Author/JM)

  7. South African Medical Journal - Vol 86, No 11 (1996)

    African Journals Online (AJOL)

    Evaluation of reflux oesophagitis with technetium-99m-labelled sucralfate · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. JH van Zyl, MG Nel, AC Otto, H de K. Grundling, E. Reinecke, JM Botha ...

  8. Avalik pöördumine seoses Kihnu rahvamajaga / Toomas Rein, Leonhard Lapin

    Index Scriptorium Estoniae

    Rein, Toomas, 1940-

    2001-01-01

    Eskiisprojektist, Arhitektuuribüroo Toomas Rein poolt 31. V 2000. a. Kihnu vallavalitsusele üle antud tehnilisest projektist (arhitektid T. Rein, L. Lapin, sisearhitekt Helle Gans), ehitaja riigihankekonkursist, ehitusfirma FKSM tööjooniste ja valmishoone erinevusest tehnilisest projektist, autoriõigusest jm

  9. Research Article

    African Journals Online (AJOL)

    2017-01-01

    Jan 1, 2017 ... temperature to develop a fine, recrystallized billet microstructure consist largely of γ ... L12 crystal structure has Al atoms at the cube corner ..... Semiatin, S.L., Shank, J.M., Saurber, W.M., Pilchak, A.L., Ballard, D.L., Zhang.

  10. 121 115 Infilling Direction and Fluid Commu

    African Journals Online (AJOL)

    2008-12-02

    Dec 2, 2008 ... Keywords: Kolo Creek, reservoir geochemistry, reservoir continuity, Niger Delta, petroleum migration ... The infilling of petroleum reservoirs is a ..... Association of Petroleum Geologists Bulletin. 81: 222–248. Hunt, J.M. (1996). Petroleum Geochemistry and. Geology. Freeman and Company, New York.

  11. Learning Theory and Prosocial Behavior

    Science.gov (United States)

    Rosenhan, D. L.

    1972-01-01

    Although theories of learning which stress the role of reinforcement can help us understand altruistic behaviors, it seems clear that a more complete comprehension calls for an expansion of our notions of learning, such that they incorporate affect and cognition. (Author/JM)

  12. Kunstnik: koomiksini jõuavad need, kellele sõnast ja pildist üksi on vähe / Joonas Sildre ; intervjueerinud Tanel Veenre

    Index Scriptorium Estoniae

    Sildre, Joonas, 1980-

    2010-01-01

    Kunstnik Joonas Sildre eesti ja soome autorikoomiksi hetkeseisust, blogikoomiksi tegijatest Soomes ja Prantsusmaal, lastekoomiksist, endast jm. Joonas Sildre ja Kalle Hakkola kureeritud koomiksinäitus "Hommik, päev, õhtu ja öö", koondnimega "FinEst Comics" Tallinnas Solarise Keskuses 5. detsembrini 2010

  13. Zmenšení dynamických účinků na předpjatých mostech

    Czech Academy of Sciences Publication Activity Database

    Frýba, Ladislav

    2005-01-01

    Roč. 14, č. 9 (2005), s. 257-260 ISSN 1210-4027 R&D Projects: GA MDS (CZ) 1F45D/013/120 Institutional research plan: CEZ:AV0Z20710524 Keywords : prestressed bridges * dynamics * prestressed strings Subject RIV: JM - Building Engineering

  14. Controlled Nuclear Fusion: Status and Outlook

    Science.gov (United States)

    Rose, David J.

    1971-01-01

    Presents the history, current concerns and potential developments of nuclear fusion as a major energy source. Controlled fusion research is summarized, technological feasibility is discussed and environmental factors are examined. Relationships of alternative energy sources as well as energy utilization are considered. (JM)

  15. Information Manager (The) - Vol 14, No 1-2 (2014)

    African Journals Online (AJOL)

    Organization As a Managerial Variable: A Study of Financial Resource Provision In University Libraries in The North Central Zone of Nigeria · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. JM Gwang, 46-57 ...

  16. Non-School Influences and Educational Disadvantage: Pre and Post-natal Nutritional Deprivation

    Science.gov (United States)

    Doll, Russell C.

    1973-01-01

    Deals with pre and post-natal malnutrition and its possible influence on the child, focusing on these points: How wide-spread and severe is the malnutrition? What might be the effects of the malnutrition at certain critical points in development? (Author/JM)

  17. Kuidas me kujundame oma linnasid ja kuidas need siis meid kujundavad = How we shape our cities, and then they shape us / Andres Sevtšuk

    Index Scriptorium Estoniae

    Sevtšuk, Andres, 1981-

    2012-01-01

    Autor käsitleb hea linna parameetreid, esitades võrdelise seose: hästi kujundatud linn = hästi elavad inimesed. Vaadeldakse Beverly Hillsi, Kowloon Walled Cityt, Tallinna viimase aja muutusi jm. Artikkel põhineb Nordic Look 2012 konverentsil "Living City" peetud ettekandel

  18. Learning with LOGO: Logo and Vectors.

    Science.gov (United States)

    Lough, Tom; Tipps, Steve

    1986-01-01

    This is the first of a two-part series on the general concept of vector space. Provides tool procedures to allow investigation of vector properties, vector addition and subtraction, and X and Y components. Lists several sources of additional vector ideas. (JM)

  19. Teaching Values in the Schools: Clarification or Indoctrination?

    Science.gov (United States)

    Baer, Richard A., Jr.

    1982-01-01

    Notes that both liberals and conservatives have criticized values clarification courses on the grounds that they assume only one correct position regarding values: ethical relativism. Maintains that values clarification fails to live up to its own claims of openness and neutrality. (Author/JM)

  20. Crack blunting, cleavage fracture in transition area and stable crack growth - investigated using the nonlinear fracture mechanics method

    International Nuclear Information System (INIS)

    Heerens, J.

    1990-01-01

    A procedure is developed which allows to estimate crack tip blunting using the stress-strain curve of the material and the J-integral. The second part deals with cleavage fracture in a quenched and tempered pressure vessel steel. It was found that within the ductile to brittle transition regime the fracture toughness is controlled by cleavage initiated at 'weak spots of the material' and by the normal stresses at the weak spots. In the last part of the paper the influence of specimen size on J-, Jm- and δ 5 -R-curves for side grooved CT-specimens under fully plastic condition is investigated. In order to characterize constraint-effects the necking of the specimens was measured. For specimens having similar constraint the parameters Jm and δ 5 yielded size independent R-curves over substantial larger amounts of crack extension than the J-integral. (orig.) With 114 figs., 10 tabs [de

  1. Nanoscale analysis of the morphology and surface stability of calcium carbonate polymorphs

    Science.gov (United States)

    Sekkal, W.; Zaoui, A.

    2013-04-01

    Under earth surface conditions, in ocean and natural water, calcium carbonate is ubiquitous, forming anhydrous and hydrous minerals. These hydrous phases are of considerable interest for their role as precursors to stable carbonate minerals. Atomistic simulation techniques have been employed here to perform a comprehensive and quantitative study of the structural and energetic stability of dry and hydrous surfaces of calcium carbonate polymorphs using two recently developed forcefields. Results show that the dry forms are prone to ductility; while hydrous phases are found to be brittle. The (001) surface of monohydrocalcite appears to be the most stable (0.99 J/m2) whereas for the ikaite phase, the (001) surface is the most stable. The corresponding value is 0.2 J/m2, i.e. even lower than the surface energy of the Beautiful computed morphology pictures are obtained with Xiao's model and are very similar to the observed SEM images.

  2. Protein expression vector and secretion signal peptide optimization to drive the production, secretion, and functional expression of the bacteriocin enterocin A in lactic acid bacteria.

    Science.gov (United States)

    Borrero, Juan; Jiménez, Juan J; Gútiez, Loreto; Herranz, Carmen; Cintas, Luis M; Hernández, Pablo E

    2011-10-20

    Replacement of the leader sequence (LS) of the bacteriocin enterocin A (LS(entA)) by the signal peptides (SP) of the protein Usp45 (SP(usp45)), and the bacteriocins enterocin P (SP(entP)), and hiracin JM79 (SP(hirJM79)) permits the production, secretion, and functional expression of EntA by different lactic acid bacteria (LAB). Chimeric genes encoding the SP(usp45), the SP(entP), and the SP(hirJM79) fused to mature EntA plus the EntA immunity genes (entA+entiA) were cloned into the expression vectors pNZ8048 and pMSP3545, under control of the inducible P(nisA) promoter, and in pMG36c, under control of the constitutive P(32) promoter. The amount, antimicrobial activity, and specific antimicrobial activity of the EntA produced by the recombinant Lactococcus lactis, Enterococcus faecium, E. faecalis, Lactobacillus sakei and Pediococcus acidilactici hosts varied depending on the signal peptide, the expression vector, and the host strain. However, the antimicrobial activity and the specific antimicrobial activity of the EntA produced by most of the LAB transformants was lower than expected from their production. The supernatants of the recombinant L. lactis NZ9000 (pNZUAI) and L. lactis NZ9000 (pNZHAI), overproducers of EntA, showed a 1.2- to 5.1-fold higher antimicrobial activity than that of the natural producer E. faecium T136 against different Listeria spp. Copyright © 2011 Elsevier B.V. All rights reserved.

  3. Solar ultraviolet light potentiates stannous chloride effects as a DNA damaging agent: a spectrophotometrical study

    International Nuclear Information System (INIS)

    Mattos, J.C.P. de; Bernardo-Filho, M.; Leitao, A.C.; Caldeira-de-Araujo, A.; Lage, C.; Leitao, A.C.

    1997-01-01

    Full text. Stannous chloride (Sn Cl 2 ) is a reducing agent widely used to reduce 99m Tc in several radio pharmaceuticals compounds. In spite of being used in nuclear medicine, its genotoxic effects are under investigation in our laboratory. In E. coli, Sn Cl 2 has been shown to have lethal and mutagenic effects, which are thought to occur mainly via active oxygen species. In order to detect some possible direct influence of Sn Cl 2 on nucleic acid, DNA, nucleotides and isolated bases were allowed to react with S N Cl 2 in an in vitro system and the effects analyzed spectro photometrically. Since Sn Cl 2 absorbs light in the UV region, we expected that UV could modify the Sn Cl 2 effects on DNA. Our results indicate that: a. Sn Cl 2 or UV (312 nm, 10 5 J/m 2 ) alone caused only slight alterations in the 260-nm absorption peak of supercoiled plasmid DNA (p U C 9.1); b. Sn Cl 2 + UV (312 nm, 10 5 J/m 2 ) led DNA (p U C 9.1) to a complete loss of its characteristic absorption in the 260-nm region; and c. when reacting with isolated A T P or T T P, Sn Cl 2 + UV (312 nm, 5 x 10 4 J/m 2 ) caused a significant decrease in their 260-nm absorption peaks, as compared to Sn CL 2 alone. Put together, our results indicate that Sn Cl 2 effects are potentiated by the action of solar UV light

  4. Solar ultraviolet and the occupational radiant exposure of Queensland school teachers: A comparative study between teaching classifications and behavior patterns.

    Science.gov (United States)

    Downs, Nathan J; Harrison, Simone L; Chavez, Daniel R Garzon; Parisi, Alfio V

    2016-05-01

    Classroom teachers located in Queensland, Australia are exposed to high levels of ambient solar ultraviolet as part of the occupational requirement to provide supervision of children during lunch and break times. We investigated the relationship between periods of outdoor occupational radiant exposure and available ambient solar radiation across different teaching classifications and schools relative to the daily occupational solar ultraviolet radiation (HICNIRP) protection standard of 30J/m(2). Self-reported daily sun exposure habits (n=480) and personal radiant exposures were monitored using calibrated polysulphone dosimeters (n=474) in 57 teaching staff from 6 different schools located in tropical north and southern Queensland. Daily radiant exposure patterns among teaching groups were compared to the ambient UV-Index. Personal sun exposures were stratified among teaching classifications, school location, school ownership (government vs non-government), and type (primary vs secondary). Median daily radiant exposures were 15J/m(2) and 5J/m(2)HICNIRP for schools located in northern and southern Queensland respectively. Of the 474 analyzed dosimeter-days, 23.0% were found to exceed the solar radiation protection standard, with the highest prevalence found among physical education teachers (57.4% dosimeter-days), followed by teacher aides (22.6% dosimeter-days) and classroom teachers (18.1% dosimeter-days). In Queensland, peak outdoor exposure times of teaching staff correspond with periods of extreme UV-Index. The daily occupational HICNIRP radiant exposure standard was exceeded in all schools and in all teaching classifications. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. Iluravi või totaalne muutumine / Madle Mühlbach

    Index Scriptorium Estoniae

    Mühlbach, Madle

    2008-01-01

    Maal asuva eramu uuest sisekujundusest. Sisearhitekt Aivar Mühlbach. Elutoa põrand on tammelaudadest, trepitagune sein ja tualettruumi seinad on kaetud kuldkollase looduskiviga. Köögist eraldatud elutoas on firma Mang kaarekujuline diivan, Poul Henningseni disainitud valgusti Artichoke jm. 13 värv. vaadet

  6. Terms of Productivity, Including the Relationship Between Productivity, Effectiveness and Efficiency.

    Science.gov (United States)

    1989-04-01

    for Awareness Juran on Planning for Quality, 1988, J.M. Juran What is Total Quality Control? The Japanese Way, 1985, Kaoru Ishikawa Guide to Quality...Control, 1982, Kaoru Ishikawa Andrews, M. (1985). Statistical Process Control: Mandatory Management Tool. Production April 1985. Bushe, G. (1988

  7. 78 FR 3422 - Notice of Receipt of Pesticide Products; Registration Applications

    Science.gov (United States)

    2013-01-16

    ... included in any currently registered pesticide products. Pursuant to the Federal Insecticide, Fungicide.... Box 667, Ames, IA 50010. Active Ingredient: Trichoderma fertile strain JM41R at 96.0%. Product Type: Fungicide. Proposed Use: Manufacturing use. Contact: Jeannine Kausch, (703) 347-8920, email address: kausch...

  8. Salto and The Garden of Eden / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2011-01-01

    Eesti edukast arhitektuuribüroost Salto. 2004. a. loodud büroo on pälvinud 38 autasu arhitektuurikonkurssidelt. Salto arhitektide projekti järgi on valminud Sõmeru vallamaja, Maanteemuuseumi välialad, Eesti Maaülikooli spordihoone, Põhuteater, Tartu Kesklinna Kooli juurdeehitus jm.

  9. Tõeliselt julge projekt = A brave project, indeed / Tarja Nurmi

    Index Scriptorium Estoniae

    Nurmi, Tarja

    2013-01-01

    Aidu püramiidid. Arhitekt: Kadarik Tüür Arhitektid (KTA). Autorid: Ott Kadarik, Mihkel Tüür. Projekt: 2011-2013. Vastavalt projektile on alale ette nähtud restoranid, veinikeldrid, ujumiskohad jm. Peapüramiid (130 m kõrge) lubab harrastada mägironimist

  10. Eluviisi määrab valikuvabadus / Meelis Press

    Index Scriptorium Estoniae

    Press, Meelis, 1965-

    1998-01-01

    Kodu loomine tähendab mõtteviisi. Erinevaid elamisvõimalusi maailmast : taotluslik looduslähedus (S. Fehni loodud kodu Norras), afisheeritud metropol, maja kui elav organism (T. Spiegelhalteri projekteeritud päikesepatareidega elamu), T. Fujimori projekteeritud võilillemaja Jaapanis, K. Masahashi plekkangaarist konstrueeritud talumaja jm.

  11. Charge and/or spin limits for black holes at a non-commutative scale

    Indian Academy of Sciences (India)

    Biplab Paik

    2017-07-12

    Jul 12, 2017 ... momentum (J) of a generalized black hole of mass M to be bounded by the condition Q2 + (J/M)2 ≤ M2, whereas ... in the classical commutative space–time background is ... scale of the Standard Model of particle physics and.

  12. Safety assessment of a steel frame using LRFD and SBRA methods

    Czech Academy of Sciences Publication Activity Database

    Václavek, L.; Chen, I.H.; Marek, Pavel

    2010-01-01

    Roč. 15, č. 1 (2010), s. 63-72 ISSN 1084-0680 R&D Projects: GA ČR(CZ) GA103/07/0557 Institutional research plan: CEZ:AV0Z20710524 Keywords : structural reliability * probabilistic reliability assessment, * Monte Carlo method Subject RIV: JM - Building Engineering

  13. Kooli roll sotsiaalses stratifikatsioonis / Silvia Kaugia

    Index Scriptorium Estoniae

    Kaugia, Silvia, 1963-

    2004-01-01

    Kooli rollist inimeste sotsialiseerijana ning sellest, kuidas õpilaste selekteerimine mõjutab nende edasist elu taastootes edukaid ja edutuid ühiskonnakihte olenemata õpilase tegelikest vaimsetest jm võimetest. Kooli ja hariduse rollist kaasaegses ühiskonnas. Artikli autor on Tartu Ülikooli õigusteaduskonna lektor ja sotsioloogiamagister

  14. Effects of energy restriction on acute adrenoceptor and metabolic responses to exercise in obese subjects

    NARCIS (Netherlands)

    Kempen, K.P.G.; Saris, W.H.M.; Senden, J.M.G.; Menheere, P.P.C.A.; Blaak, E.E.; van Baak, M.A.

    1994-01-01

    Effects of energy restriction on acute adrenoceptor and metabolic responses to exercise in obese subjects. Kempen KP, Saris WH, Senden JM, Menheere PP, Blaak EE, van Baak MA. Department of Human Biology, University of Limburg, Maastricht, The Netherlands. This study was intended to investigate the

  15. Effects of calcium antagonists on hypertension and diastolic function

    African Journals Online (AJOL)

    1989-08-05

    Aug 5, 1989 ... and improve myocardial function. Digitalis compounds such as digoxin are not appropriate therapy for diastolic dysfunction and should be avoided. REFERENCES. I. Fouad FM, Slominski JM, Tarazi RC. Left ventricular diastolic function in hypertension: relation to left ventricular mass and systolic function.

  16. The fish egg microbiome

    NARCIS (Netherlands)

    Liu, Y.

    2016-01-01

    Y. Liu

    Prof. dr. F. Govers (promotor); Prof. dr. J.M. Raaijmakers (promotor); Dr. I. de Bruijn (co-promotor); Wageningen University, 13 June 2016, 170 pp.

    The fish egg microbiome: diversity and activity against the oomycete pathogen

  17. Open Veterinary Journal - Vol 6, No 2 (2016)

    African Journals Online (AJOL)

    Cryptosporidium varanii infection in leopard geckos (Eublepharis macularius) in Argentina · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. A Dellarupe, JM Unzaga, G Moré, M Kienast, A Larsen, C Stiebel, M Rambeaud, MC Venturini, 98-101.

  18. Treating Duchenne Cardiomyopathy in the Mouse Model by Gene Repair

    Science.gov (United States)

    2017-08-01

    Photoregulated Gene Expression for Spatiotemporal Control of Morphogenesis Time Commitments: 0 Supporting Agency: NSF Career Award, CBET-1151035...vector toolkit for human gene therapy. Mol Ther 2006, 14:316-327. 20. Gao G, Vandenberghe LH, Wilson JM: New recombinant serotypes of AAV vectors. Curr

  19. Disease: H00509 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Graul-Neumann LM, van Hagen JM, van Hest L, Horovitz D, Melki J, Partsch CJ, Plauchu H, Rajab...H, van Hest L, Lund AM, Michaud J, Oley C, Patel C, Rajab A, Skidmore DL, Stewart H, Tauber M, Munnich A, Co

  20. Estrogen induces axonal outgrowth in the nucleus retroambiguus-lumbosacral motoneuronal pathway in the adult female cat

    NARCIS (Netherlands)

    VanderHorst, VGJM; Holstege, G

    1997-01-01

    In 1995, we discovered a new pathway in the cat, which originates from the nucleus retroambiguus (NRA) and terminates in a distinct set of lumbosacral hindlimb, axial, and pelvic floor motoneuronal cell groups [VanderHorst VG.JM, Holstege G (1995) Caudal medullary pathways to lumbosacral