75 FR 58425 - Notice of Intent to Repatriate Cultural Items: American Museum of Natural History, New York, NY

Science.gov (United States)

2010-09-24

... Museum of Natural History, New York, NY, that meets the definition of unassociated funerary objects under... remains as a ``Pima ... medicine man.'' The two associated funerary objects were a pair of metal spurs. In...

Síndrome de Weill-Marchesani Weill-Marchesani syndrome

Directory of Open Access Journals (Sweden)

Seydel Legra Nápoles

2009-12-01

Full Text Available El síndrome de Weill-Marchesani es un desorden genético poco frecuente del tejido conectivo con afectación ocular. Desde su descripción por Weill y Marchesani en 1932 y 1939, se han descrito patrones de herencia autosómica dominante y recesiva. En general estos pacientes se caracterizan por baja talla, braquidactilia con rigidez articular, microsferofaquia, miopía lenticular progresiva, luxación cristaliniana, y glaucoma secundario. Se presentan las características oftalmológicas y clínicas de una paciente a quien se le diagnosticó este síndrome genético. Procedía de una familia de 4 miembros donde uno de ellos presentaba similares características (padre, no se detectaron malformaciones cardiovasculares asociadas pero se recogen antecedentes de autoagresión. El desempeño del oftalmólogo en su diagnóstico precoz y manejo, es de vital importancia, de esta forma se podría lograr una rehabilitación visual y la consecuente incorporación a una vida socialmente útil.Weil Marchesani syndrome is a rare genetic disorder of the connective tissue with ocular effect. Since the description of this disease by Weill and Marchesani in 1932 and 1939 respectively, patterns of autosomal dominant and recessive inheritance have been outlined. In general, these patients are characterized by small size, brachydactilia, joint rigidity, microspherophakia, progressive lenticular myopia, crystalline luxation and secondary glaucoma. This paper presented the ophthalmologic and clinical characteristics of a female patient who was diagnosed with this genetic syndrome. She came from a four-member family in which one of them presented with similar characteristics (father; there were not associated cardiovascular malformations, but self-attack history was included. The ophthalmologist's performance in the early diagnosis and management of the disease is of vital importance, because in this way, visual rehabilitation could be materialized, with subsequent

Retinal Vascular Tortuosity in a Patient with Weill-Marchesani Syndrome

Directory of Open Access Journals (Sweden)

Kevin Gallagher

2011-01-01

Full Text Available Weill-Marchesani syndrome (WMS is a rare connective tissue disorder with characteristic phenotypic skeletal and ocular manifestations. A 28-year-old myopic female presented with an 8-month history of bilateral blurred vision. On examination, she was noted to be of short stature with brachydactyly. On ocular examination, she was found to be spherophakic with bilateral inferiorly subluxated lenses. Serum and urine homocysteine were normal and a syphilis screen was negative. A diagnosis of Weill-Marchesani syndrome was made. Fundoscopy revealed bilateral tortuous retinal vessels. We report the first illustrated case of retinal vascular tortuosity as an ocular manifestation of Weill-Marchesani syndrome.

78 FR 56609 - Drawbridge Operation Regulations; Reynolds Channel, Lawrence, NY

Science.gov (United States)

2013-09-13

... Regulations; Reynolds Channel, Lawrence, NY AGENCY: Coast Guard, DHS. ACTION: Notice canceling temporary... Beach Bridge, mile 0.4, across Reynolds Channel, at Lawrence, New York. The owner of the bridge, Nassau... published a temporary deviation entitled ``Drawbridge Operation Regulations; Reynolds Channel, Lawrence, NY...

Anesthesia for the patient undergoing total knee replacement: current status and future prospects

OpenAIRE

Turnbull,Zachary; Sastow,Dahniel; Giambrone,Gregory; Tedore,Tiffany

2017-01-01

Zachary A Turnbull, Dahniel Sastow, Gregory P Giambrone, Tiffany Tedore Department of Anesthesiology, Weill Cornell Medical College, New York, NY, USA Abstract: Total knee arthroplasty (TKA) has become one of the most common orthopedic surgical procedures performed nationally. As the population and surgical techniques for TKAs have evolved over time, so have the anesthesia and analgesia used for these procedures. General anesthesia has been the dominant form of anes...

Argon laser peripheral iridoplasty for angle-closure glaucoma in sibilings with weill-marchesani syndrome.

Science.gov (United States)

Ritch, R; Solomon, L D

1992-01-01

A patient with Weill-Marchesani syndrome and angle-closure glaucoma had persistent appositional closure after laser iridotomy that was unrelieved by topical application of either miotic or cycloplegic agents. Argon laser peripheral iridoplasty successfully opened the angle. The patient's sister also had Weill-Marchesani syndrome and angle closure unrelieved by laser iridotomy. Angle closure in Weill-Marchesani syndrome and the response to laser iridotomy and treatment with either miotic or cycloplegic agents may be complex and depends on the relative proportion of pupillary block as a mechanism underlying the angle closure, the functional status of the zonular apparatus, and the degree of angle crowding by the peripheral iris in the presence or absence of peripheral anterior synechiae.

Evidence of the Adoption and Implementation of a Statewide Childhood Obesity Prevention Initiative in the New York State WIC Program: The "NY Fit WIC" Process Evaluation

Science.gov (United States)

Sekhobo, Jackson P.; Egglefield, Katherine; Edmunds, Lynn S.; Shackman, Gene

2012-01-01

Process evaluations are critical in determining whether outcome evaluations are warranted. This study assessed the extent to which a childhood obesity prevention initiative, "NY Fit WIC", was adopted and implemented by the New York State Supplemental Nutrition Program for Women, Infants and Children (WIC). Process data came from…

Effect of vitamin C supplementation on stroke recovery: A case-control study

OpenAIRE

Rabadi, Meheroz H; Kristal, Bruce S

2007-01-01

Meheroz H Rabadi1, Bruce S Kristal2,31Burke Rehabilitation Hospital, an affiliate of Weill Medical College of Cornell Medical College, White Plains, NY, USA; 2Burke Medical Research Institute, an affiliate of Weill Medical College of Cornell Medical College, White Plains, NY, USA; 3Department of Neuroscience, Cornell University Medical College, White Plains, NY, USABackground and purpose: Epidemiological studies have associated increased dietary intake of antioxidants (vitamin C, E, and &beta...

Libraries in New York: MedlinePlus

Science.gov (United States)

... 212-410-8142 http://library.nycpm.edu NYU School of Medicine Health Sciences Library 550 First Avenue New York, NY 10016-6402 ... 4743 http://wernerlibrary.org/wellness University of Rochester School of Medicine and Dentistry Edward G. Miner Library 601 Elmwood Avenue Rochester, NY 14642 585-275- ...

77 FR 40518 - Swim Events in the Captain of the Port New York Zone; Hudson River, East River, Upper New York...

Science.gov (United States)

2012-07-10

... 1625-AA00 Swim Events in the Captain of the Port New York Zone; Hudson River, East River, Upper New York Bay, Lower New York Bay; New York, NY ACTION: Final rule. SUMMARY: The Coast Guard is establishing seven temporary safety zones for swim events within the Captain of the Port (COTP) New York Zone. These...

New York City, New York: Solar in Action (Brochure)

Energy Technology Data Exchange (ETDEWEB)

2011-10-01

This brochure provides an overview of the challenges and successes of New York City, NY, a 2007 Solar America City awardee, on the path toward becoming a solar-powered community. Accomplishments, case studies, key lessons learned, and local resource information are given.

78 FR 36242 - Notice of Intent To Repatriate Cultural Items: New York State Museum, Albany, NY

Science.gov (United States)

2013-06-17

..., Rensselaer County, NY, by Reverend O.C. Auringer of Troy, NY. Museum records indicate that the cultural items..., and Saratoga Counties, NY, by Mr. Dwinel F. Thompson of Troy, NY. Museum records indicate that the... collections. From the former Laureate Grounds in Troy, Rensselaer County, NY, the 90 unassociated funerary...

75 FR 13454 - Special Local Regulation, Fran Schnarr Open Water Championships, Huntington Bay, NY

Science.gov (United States)

2010-03-22

...-AA08 Special Local Regulation, Fran Schnarr Open Water Championships, Huntington Bay, NY AGENCY: Coast... navigable waters of Huntington Bay, New York due to the annual Fran Schnarr Open Water Championships. The..., ``Special Local Regulation, Fran Schnarr Open Water Championships, Huntington Bay, NY'' (Docket number USCG...

75 FR 38710 - Special Local Regulation, Fran Schnarr Open Water Championships, Huntington Bay, NY

Science.gov (United States)

2010-07-06

...-AA08 Special Local Regulation, Fran Schnarr Open Water Championships, Huntington Bay, NY AGENCY: Coast... Regulation on the navigable waters of Huntington Bay, New York due to the annual Fran Schnarr Open Water... ``Special Local Regulation, Fran Schnarr Open Water Championships, Huntington Bay, NY'' in the Federal...

75 FR 29727 - Reorganization of Foreign-Trade Zone 37 Under Alternative Site Framework Orange County, NY

Science.gov (United States)

2010-05-27

... Zone 37 Under Alternative Site Framework Orange County, NY Pursuant to its authority under the Foreign... reorganization of general-purpose zones; Whereas, Orange County, New York, grantee of Foreign-Trade Zone 37... under the ASF with a service area of Orange County, New York, adjacent to the New York/Newark Customs...

EnviroAtlas - New York, NY - Ecosystem Services by Block Group

Data.gov (United States)

U.S. Environmental Protection Agency — This EnviroAtlas dataset presents environmental benefits of the urban forest in 6,378 block groups in New York City, New York. Carbon attributes, temperature...

78 FR 66265 - Drawbridge Operation Regulations; Reynolds Channel, Lawrence, NY

Science.gov (United States)

2013-11-05

... Regulations; Reynolds Channel, Lawrence, NY AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation... from the regulations governing the operation of the Atlantic Beach Bridge, mile 0.4, across Reynolds.... SUPPLEMENTARY INFORMATION: The Atlantic Beach Bridge, across Reynolds Channel, mile 0.4, at Lawrence, New York...

78 FR 56610 - Drawbridge Operation Regulations; Reynolds Channel, Lawrence, NY

Science.gov (United States)

2013-09-13

... Regulations; Reynolds Channel, Lawrence, NY AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation... from the regulations governing the operation of the Atlantic Beach Bridge, mile 0.4, across Reynolds.... SUPPLEMENTARY INFORMATION: The Atlantic Beach Bridge, across Reynolds Channel, mile 0.4, at Lawrence, New York...

76 FR 59177 - New York Disaster #NY-00110

Science.gov (United States)

2011-09-23

... York: Chemung, Cortland, Greene, Herkimer, Madison, Montgomery, Oneida, Schoharie, Sullivan, Tompkins... Federal Domestic Assistance Numbers 59002 and 59008) James E. Rivera, Associate Administrator for Disaster...

77 FR 37316 - Drawbridge Operation Regulations; Reynolds Channel, Nassau, NY

Science.gov (United States)

2012-06-21

... Regulations; Reynolds Channel, Nassau, NY AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from... regulations governing the operation of the Long Beach Bridge, mile 4.7, across Reynolds Channel, at Nassau...: The Long Beach Bridge, across Reynolds Channel, mile 4.7, at Nassau, New York, has a vertical...

78 FR 34893 - Drawbridge Operation Regulations; Reynolds Channel, Lawrence, NY

Science.gov (United States)

2013-06-11

... Regulations; Reynolds Channel, Lawrence, NY AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation... from the regulations governing the operation of the Atlantic Beach Bridge, mile 0.4, across Reynolds... Reynolds Channel, mile 0.4, at Lawrence, New York, has a vertical clearance in the closed position of 25...

76 FR 60733 - Drawbridge Operation Regulations; Narrow Bay, Smith Point, NY

Science.gov (United States)

2011-09-30

... Operation Regulations; Narrow Bay, Smith Point, NY AGENCY: Coast Guard, DHS. ACTION: Notice of temporary... deviation from the regulation governing the operation of the Smith Point Bridge, 6.1, across Narrow Bay, between Smith Point and Fire Island, New York. The deviation is necessary to facilitate bridge...

75 FR 42608 - Safety Zone; Lyme Community Days, Chaumont Bay, NY

Science.gov (United States)

2010-07-22

...-AA00 Safety Zone; Lyme Community Days, Chaumont Bay, NY AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing a temporary safety zone for Lyme Community Days Fireworks on Chaumont Bay, Lyme, New York. All vessels are prohibited from transiting the zone except as...

76 FR 33639 - Safety Zone; New York Water Taxi 10th Anniversary Fireworks

Science.gov (United States)

2011-06-09

...-AA00 Safety Zone; New York Water Taxi 10th Anniversary Fireworks, Upper New York Bay, Red Hook, NY... New York Water Taxi. The fireworks will commence at 9 p.m. on June 21, 2011 and will last... CFR Part 165 Harbors, Marine safety, Navigation (water), Reporting and recordkeeping requirements...

EnviroAtlas - New York, NY - BenMAP Results by Block Group

Data.gov (United States)

U.S. Environmental Protection Agency — This EnviroAtlas dataset demonstrates the effect of changes in pollution concentration on local populations in 6,378 block groups in New York City, New York. The US...

78 FR 23845 - Drawbridge Operation Regulations; Narrow Bay, Smith Point, NY

Science.gov (United States)

2013-04-23

... Operation Regulations; Narrow Bay, Smith Point, NY AGENCY: Coast Guard, DHS. ACTION: Notice of temporary... deviation from the regulation governing the operation of the Smith Point Bridge, mile 6.1, across Narrow Bay, between Smith Point and Fire Island, New York. The deviation is necessary to facilitate the Smith Point...

75 FR 227 - Drawbridge Operation Regulations; Harlem River, New York, NY

Science.gov (United States)

2010-01-05

..., and require all the moveable bridges across the Harlem River, except the Spuyten Duyvil Bridge, to... eleven moveable bridges across the Harlem River provide the following vertical clearances in the closed... bridges across the Harlem River at New York City, New York. This final rule revises the drawbridge...

76 FR 56857 - New York Disaster Number NY-00108

Science.gov (United States)

2011-09-14

... Counties: (Economic Injury Loans Only): New York: Herkimer, Madison, Oneida All other information in the...) James E. Rivera, Associate Administrator for Disaster Assistance. [FR Doc. 2011-23428 Filed 9-13-11; 8...

New York esophageal squamous cell carcinoma-1 and cancer immunotherapy.

Science.gov (United States)

Esfandiary, Ali; Ghafouri-Fard, Soudeh

2015-01-01

New York esophageal squamous cell carcinoma 1 (NY-ESO-1) is a known cancer testis gene with exceptional immunogenicity and prevalent expression in many cancer types. These characteristics have made it an appropriate vaccine candidate with the potential application against various malignancies. This article reviews recent knowledge about the NY-ESO-1 biology, function, immunogenicity and expression in cancers as well as and the results of clinical trials with this antigen.

NY-ESO-1 Based Immunotherapy of Cancer: Current Perspectives

Directory of Open Access Journals (Sweden)

Remy Thomas

2018-05-01

Full Text Available NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy. In this review, we provide background information on NY-ESO-1 expression and function in normal and cancerous tissues. Furthermore, NY-ESO-1-specific immune responses have been observed in various cancer types; however, their utility as biomarkers are not well determined. Finally, we describe the immune-based therapeutic options targeting NY-ESO-1 that are currently in clinical trial. We will highlight the recent advancements made in NY-ESO-1 cancer vaccines, adoptive T cell therapy, and combinatorial treatment with checkpoint inhibitors and will discuss the current trends for future NY-ESO-1 based immunotherapy. Cancer treatment has been revolutionized over the last few decades with immunotherapy emerging at the forefront. Immune-based interventions have shown promising results, providing a new treatment avenue for durable clinical responses in various cancer types. The majority of successful immunotherapy studies have been reported in liquid cancers, whereas these approaches have met many challenges in solid cancers. Effective immunotherapy in solid cancers is hampered by the complex, dynamic tumor microenvironment that modulates the extent and phenotype of the antitumor immune response. Furthermore, many solid tumor-associated antigens are not private but can be found in normal somatic tissues, resulting in minor to detrimental off-target toxicities. Therefore, there is an ongoing effort to identify tumor-specific antigens to target using various immune-based modalities. CTAs are considered good candidate targets for immunotherapy as they are characterized by a restricted expression in normal somatic tissues

The hidden and implicit curricula in cultural context: new insights from Doha and New York.

Science.gov (United States)

Fins, Joseph J; Rodríguez del Pozo, Pablo

2011-03-01

The authors report their longitudinal experience teaching a clerkship in clinical ethics and palliative care at the Weill Cornell Medical College campuses in New York and Doha. This course uses participant observation and reflective practice to counteract the hidden curriculum when learning about clinical ethics and end-of-life care. The authors consider how this formal element of the curriculum is influenced by the implicit and hidden curricula in different cultural contexts and how these differing venues affect communication and information exchange, using the anthropological concept of high- and low-context societies. The authors' analysis provides additional information on Weill Cornell's educational efforts in the medical humanities, bioethics, and palliative care across the curriculum and across cultural settings. By contrasting high-context Doha, where much information is culturally embedded and seemingly hidden, with low-context New York, where information is made overt, the authors theorize that in each setting, the proportion of implicit and explicit curricular elements is determined by the extramural cultural environment. They argue that there are many hidden and implicit curricula and that each is dependent on modes of communication in any given setting. They assert that these variations can be seen not only across differing societies but also, for example, among individual U.S. medical schools because of local custom, history, or mission. Because these contextual factors influence the relative importance of what is implicit and explicit in the student's educational experience, medical educators need to be aware of their local cultural contexts in order to engage in effective pedagogy.

78 FR 56607 - Drawbridge Operation Regulation; Hudson River, Troy and Green Island, NY

Science.gov (United States)

2013-09-13

...-AA09 Drawbridge Operation Regulation; Hudson River, Troy and Green Island, NY AGENCY: Coast Guard, DHS... operation of the highway bridge across the Hudson River, mile 152.7, between Troy and Green Island, New York... Street Bridge, mile 155.4, between Troy and Cohoes which has been converted to a fixed bridge. It is...

78 FR 27856 - Golden Nematode; Removal of Regulated Areas in Livingston and Steuben Counties, NY

Science.gov (United States)

2013-05-13

.... APHIS-2012-0079] Golden Nematode; Removal of Regulated Areas in Livingston and Steuben Counties, NY... nematode regulations by removing areas in Livingston and Steuben Counties in New York from the list of... nematode, and we determined that regulation of these areas was no longer necessary. As a result of that...

75 FR 76943 - Regulated Navigation Area; Hudson River South of the Troy Locks, NY

Science.gov (United States)

2010-12-10

...-AA11 Regulated Navigation Area; Hudson River South of the Troy Locks, NY AGENCY: Coast Guard, DHS... Navigation Area (RNA) on the navigable waters of the Hudson River in New York, south of the Troy Locks. This... within the waters of the Hudson River south of the Troy Locks when ice is a threat to navigation. DATES...

76 FR 8654 - Regulated Navigation Area; Hudson River South of the Troy Locks, NY

Science.gov (United States)

2011-02-15

...-AA11 Regulated Navigation Area; Hudson River South of the Troy Locks, NY AGENCY: Coast Guard, DHS... navigable waters of the Hudson River in New York, south of the Troy Locks. This action is necessary to... Hudson River south of the Troy Locks when ice is a threat to navigation. DATES: This rule is effective in...

Summer indoor heat exposure and respiratory and cardiovascular distress calls in New York City, NY, U.S.

Science.gov (United States)

Uejio, C K; Tamerius, J D; Vredenburg, J; Asaeda, G; Isaacs, D A; Braun, J; Quinn, A; Freese, J P

2016-08-01

Most extreme heat studies relate outdoor weather conditions to human morbidity and mortality. In developed nations, individuals spend ~90% of their time indoors. This pilot study investigated the indoor environments of people receiving emergency medical care in New York City, NY, U.S., from July to August 2013. The first objective was to determine the relative influence of outdoor conditions as well as patient characteristics and neighborhood sociodemographics on indoor temperature and specific humidity (N = 764). The second objective was to determine whether cardiovascular or respiratory cases experience hotter and more humid indoor conditions as compared to controls. Paramedics carried portable sensors into buildings where patients received care to passively monitor indoor temperature and humidity. The case-control study compared 338 respiratory cases, 291 cardiovascular cases, and 471 controls. Intuitively, warmer and sunnier outdoor conditions increased indoor temperatures. Older patients who received emergency care tended to occupy warmer buildings. Indoor-specific humidity levels quickly adjusted to outdoor conditions. Indoor heat and humidity exposure above a 26 °C threshold increased (OR: 1.63, 95% CI: 0.98-2.68, P = 0.056), but not significantly, the proportion of respiratory cases. Indoor heat exposures were similar between cardiovascular cases and controls. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

77 FR 10960 - Security Zone, East River and Bronx Kill; Randalls and Wards Islands, NY

Science.gov (United States)

2012-02-24

...'' W (Port Morris Stacks), and all waters of the Bronx Kill southeast of the Bronx Kill Rail Road...-AA87 Security Zone, East River and Bronx Kill; Randalls and Wards Islands, NY AGENCY: Coast Guard, DHS... waters of the East River and Bronx Kill, in the vicinity of Randalls and Wards Islands, New York. This...

77 FR 38486 - Safety Zone; City of Tonawanda July 4th Celebration, Niagara River, Tonawanda, NY

Science.gov (United States)

2012-06-28

... 1625-AA00 Safety Zone; City of Tonawanda July 4th Celebration, Niagara River, Tonawanda, NY AGENCY... safety zone on the Niagara River, Tonawanda, New York. This safety zone is intended to restrict vessels from a portion of the Niagara River during the City of Tonawanda July 4th Celebration fireworks on July...

Duration of US residence is associated with overweight risk in Filipino immigrants living in NY metro area

Science.gov (United States)

Afable, Aimee; Ursua, Rhodora; Wyatt, Laura C.; Aguilar, David; Kwon, Simona C.; Islam, Nadia S.; Trinh-Shevrin, Chau

2015-01-01

We examined the association between years living in the US and overweight risk among a community sample of Filipino adult immigrants living in the New York (NY) metropolitan area. We found a significant and adverse association between years living in the US and overweight risk. Compared to Filipinos who lived in the US less than 5 years, those who lived in the US 10 years or longer had a higher overweight risk; this association was only present among Filipinos who migrated to NY metropolitan area at 30 years or younger. Studies on causal mechanisms explaining this pattern are needed. PMID:26605951

Graphic tobacco warning labels – an improper solution?

Directory of Open Access Journals (Sweden)

Salvi JD

2014-07-01

Full Text Available Joshua D SalviWeill Cornell Medical College, New York, NY, USAIn June 2009, President Barack Obama signed into law the Family Smoking Prevention and Tobacco Control Act (HR 1256. This legislation required that all tobacco products and advertising must have a graphic warning covering 50 percent of the front and back of the package. The US Food and Drug Administration (FDA has proposed a number of graphic designs, and the final designs were submitted in June, 2011. The proposed designs include grotesque imagery in an attempt to dissuade smoking in the USA. However, these graphic labels were invalidated in court due to violation of freedom-of-speech rights. Independent from that point, these labels, if appealed, would do more harm than good from a public health perspective. 

Pachychoroid neovasculopathy in extramacular choroidal neovascularization

Directory of Open Access Journals (Sweden)

Gupta MP

2016-07-01

Full Text Available Mrinali Patel Gupta, Irene Rusu, Carly Seidman, Anton Orlin, Donald J D’Amico, Szilard Kiss Department of Ophthalmology, Weill Cornell Medicine, New York-Presbyterian Hospital, New York, NY, USA Purpose: To review a series of extramacular choroidal neovascular membranes (CNVMs in the context of their choroidal features, as determined by optical coherence tomography (OCT.Methods: Patients with extramacular CNVMs were identified from a tertiary care center through a review of records. The charts and cases were reviewed using multimodal imaging including fundus photography, OCT, fluorescein angiography (FA, and indocyanine angio­graphy (ICG.Results: Of six patients with extramacular CNVMs evaluated in this series, four patients (66.7% exhibited pachychoroidopathy on OCT imaging under or adjacent to the extramacular CNVM. All four of these patients also exhibited pachychoroidopathy in the macular OCT distant from the CNVM.Conclusion: Pachychoroidopathy is implicated in some cases of extramacular CNVMs. This represents the first report, to our knowledge, of pachychoroidopathy in extramacular CNVM. Keywords: choroidal neovascularization, pachychoroidopathy, pachychoroid neovasculopathy, peripheral disciform lesions, extramacular choroidal neovascularization, polypoidal choroidal vasculopathy

An illustrative case of Léri-Weill dyschondrosteosis

Directory of Open Access Journals (Sweden)

Renata de Lima

2008-01-01

Full Text Available We report on a girl presenting Léri-Weill dyschondrosteosis (LWD due to deletion of the SHOX gene. Her family included individuals with short stature alone or with both short stature and mesomelia or Madelung's deformity. The deletion was demonstrated through detection of hemizygosity for microsatellite markers SHOX-CA repeat, DXYS10092, DXYS10093 and DXYS10091 localized around the SHOX gene, with retention of paternal alleles in the proband and three of her sisters who had short stature as the only clinical feature. Hemizygosity for these loci was also observed in their mother, who had short stature too. The deletion in the proband was however larger, including locus DXY10083. The proband's only sister with normal height did not carry the deletion. Family history suggests transmission of the deletion from the proband's maternal great-grandfather to her grandfather via the Y chromosome, and from the grandfather to the proband's mother via the X chromosome after crossing-over in the pseudoautosomal region proximal to the SHOX gene.

St. Lawrence Seaway N.Y. Feasibility Study for Additional Locks and Other Navigation Improvements: Plan of Study. Revision.

Science.gov (United States)

1979-11-01

work in the marketing area in its attempt to establish a viable direct container trade. 48 200 FIG11E lI-C-1l POE LOCK CAPACITY ANALYSIS 8UJ04*1 190 ISO ...Avenue, SW Washington, DC 20591 Commissioner New York State Dept. of Comerce 112 State Street Albany, NY 12207 Commissioner New York State Dept. of Er...In the spring, we hAy’: exc,311ent fishing. AL ISO *PP59001111006V SUPLOVIS C.amotb a.,t COIN*m C lobt.. V*. MOM"ua. h"g C. 5.4. tftamw Ua A. 10"I."Hoa

75 FR 13131 - Notice of Intent To Prepare an Environmental Impact Statement (EIS) for the Sale of Plum Island, NY

Science.gov (United States)

2010-03-18

... the anticipated sale of Plum Island, New York and an ancillary support facility at Orient Point, New...) for the Sale of Plum Island, NY AGENCY: Office of Real Property Utilization & Disposal; General...: Plum Island is an 840-acre island located approximately 1.5 miles off the northeast tip of Orient Point...

Complete genome sequence of a tomato infecting tomato mottle mosaic virus in New York

Science.gov (United States)

Complete genome sequence of an emerging isolate of tomato mottle mosaic virus (ToMMV) infecting experimental nicotianan benthamiana plants in up-state New York was obtained using small RNA deep sequencing. ToMMV_NY-13 shared 99% sequence identity to ToMMV isolates from Mexico and Florida. Broader d...

Leri-Weill dyschondrosteosis: An under-recognised cause of short stature

Directory of Open Access Journals (Sweden)

E G Lemire

2009-03-01

Full Text Available Short stature is a frequent presenting problem in the pediatric population. Various causes including endocrinopathies, skeletal dysplasias, dysmorphic syndromes and malabsorption have been implicated. In girls with short stature, Turner syndrome is frequently considered in the differential diagnosis and can easily be ruled out with chromosome analysis. However, it is not uncommon for a child to have no identifiable cause of their short stature. ?FOR Advances in the field of genetics have estimated that about 2% of idiopathic short stature is related to haploinsufficiency of the Short stature homeobox (SHOX gene, which is found on the short arm of the X and Y chromosomes in the pseudoautosomal region. Heterozygous carriers of SHOX mutations may be minimally affected or may present with disproportionate short stature, Madelung deformity and other radiographic findings as in Leri-Weill dyschondrosteosis (LWD. In this article, we report on a 14-year old girl with mesomelic short stature and bilateral Madelung deformities caused by LWD and describe the radiographic findings.

Proton pump inhibitors for the treatment of patients with erosive esophagitis and gastroesophageal reflux disease: current evidence and safety of dexlansoprazole

Directory of Open Access Journals (Sweden)

Mermelstein J

2016-07-01

Full Text Available Joseph Mermelstein,1 Alanna Chait Mermelstein,2 Maxwell M Chait,3 1Department of Medicine, Mount Sinai Beth Israel/Icahn School of Medicine, 2Department of Psychiatry, New York Presbyterian Hospital/Weill Cornell Medicine, 3Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA Abstract: Gastroesophageal reflux disease is the most common upper gastroenterology disorder in the US. It is associated with a variety of complications and significantly impacts quality of life. Proton pump inhibitors are the most effective treatment. Dexlansoprazole modified release (MR is a proton pump inhibitor that employs a novel release formulation that prolongs its absorption and allows for more flexibility in dosing. Dexlansoprazole MR can be dosed without regard to food intake or time of day, and once-daily dosing may replace twice-daily dosing of other agents. Dexlansoprazole MR is effective for healing and maintenance of erosive esophagitis, and for the treatment of nonerosive disease, including nocturnal gastroesophageal reflux disease. Dexlansoprazole MR is safe and well tolerated, and can improve quality of life. Keywords: dexlansoprazole, proton pump inhibitors, gastroesophageal reflux disease, erosive esophagitis

Clinical and molecular characterization of Chilean patients with Léri-Weill dyschondrosteosis.

Science.gov (United States)

Rodríguez, Fernando Adrián; Unanue, Nancy; Hernandez, María Isabel; Basaure, Javiera; Heath, Karen Elise; Cassorla, Fernando

2013-01-01

Léri-Weill dyschondrosteosis (LWD) is a mesomelic dysplasia with disproportionate short stature associated with short stature homeobox-containing gene (SHOX) haploinsufficiency. The objective of this study was to improve the diagnosis of patients with suspected LWD through molecular analysis. Twelve patients from 11 families with a clinical diagnosis of LWD were analyzed with multiplex ligation-dependent probe amplification to detect deletions and duplications of SHOX and its enhancer regions. High resolution melting and sequencing was employed to screen for mutations in SHOX coding exons. The molecular-based screening strategy applied in these patients allowed detection of five SHOX deletions and two previously unreported SHOX missense mutations. Molecular studies confirmed the clinical diagnosis of LWD in seven out of 12 patients, which provided support for therapeutic decisions and improved genetic counseling in their families.

Factors Influencing Divergent Patterns of Phosphorus Availability in NY and PA Biogeochemical `Hotspots'

Science.gov (United States)

Saia, S. M.; Hofmeister, K.; Regan, J. M.; Buda, A. R.; Carrick, H. J.; Walter, M. T.

2016-12-01

Anthropogenic alteration of the soil phosphorus (P) cycle leads to subsequent water quality issues in agricultural dominated watersheds. In the humid Northeastern United States (NE US), variably saturated areas can generate surface runoff that transports P and stimulates biogeochemical processes; these hydrologically dynamic locations are often called biogeochemical `hotspots'. Many studies have evaluated nitrogen and carbon cycling in biogeochemical hot spots but few have focused on P. We hypothesized seasonally wet parts of the landscape (i.e., hotspots) have smaller biologically available P pools because runoff events frequently carry away nutrients like P. To test this hypothesis, we generated soil wetness index (SWI) maps from soil (SURRGO) and elevation (LiDAR rescaled to 3 m) data and used these maps to direct seasonal soil sampling near Klingerstown, Pennsylvania (PA) and Ithaca, New York (NY). We collected 5cm deep soil samples in PA (bimonthly) and NY (monthly) along soil moisture gradients for a range of land cover types (forest, fallow, and cropped) from May through October. We measured soil moisture in the field and percent organic matter (OM), pH, and three increasingly strong soil P extractions (dilute-salt-extractable P, oxalate-extractable P, and total-extractable P) in the laboratory. Our results indicated a negative relationship between dilute-salt-extractable P concentrations and SWI in PA and no relationship between these same variables in NY. We also found positive relationships between each of the three P extractions in PA but only a positive relationship between oxalate-extractable P and total-extractable P in NY. Our findings in PA support our hypothesis; namely, less biologically available P (i.e. dilute-salt-extractable P) is found in wetter areas of the landscape. However, divergent P availability patterns in NY point to further complexities and confounding variables in our understanding in soil P processes. Further studies will look

Recent trends in the gene therapy of β-thalassemia

Directory of Open Access Journals (Sweden)

Finotti A

2015-02-01

Full Text Available Alessia Finotti,1–3 Laura Breda,4 Carsten W Lederer,6,7 Nicoletta Bianchi,1–3 Cristina Zuccato,1–3 Marina Kleanthous,6,7 Stefano Rivella,4,5 Roberto Gambari1–3 1Laboratory for the Development of Gene and Pharmacogenomic Therapy of Thalassaemia, Biotechnology Centre of Ferrara University, Ferrara, Italy; 2Associazione Veneta per la Lotta alla Talassemia, Rovigo, Italy; 3Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, Ferrara University, Ferrara, Italy; 4Department of Pediatrics, Division of Haematology/Oncology, Weill Cornell Medical College, New York, NY, USA; 5Department of Cell and Development Biology, Weill Cornell Medical College, New York, NY, USA; 6Department of Molecular Genetics Thalassaemia, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus; 7Cyprus School of Molecular Medicine, Nicosia, Cyprus Abstract: The β-thalassemias are a group of hereditary hematological diseases caused by over 300 mutations of the adult β-globin gene. Together with sickle cell anemia, thalassemia syndromes are among the most impactful diseases in developing countries, in which the lack of genetic counseling and prenatal diagnosis have contributed to the maintenance of a very high frequency of these genetic diseases in the population. Gene therapy for β-thalassemia has recently seen steadily accelerating progress and has reached a crossroads in its development. Presently, data from past and ongoing clinical trials guide the design of further clinical and preclinical studies based on gene augmentation, while fundamental insights into globin switching and new technology developments have inspired the investigation of novel gene-therapy approaches. Moreover, human erythropoietic stem cells from β-thalassemia patients have been the cellular targets of choice to date whereas future gene-therapy studies might increasingly draw on induced pluripotent stem cells. Herein, we summarize the most

77 FR 16849 - Notice of Realignment/Merger of Five Regional Audit Offices: Boston, MA Will Merge With New York...

Science.gov (United States)

2012-03-22

... of Five Regional Audit Offices: Boston, MA Will Merge With New York, NY; and the Gulf Coast Region... result from the reorganization; (3) a discussion of the impact on the local economy; and (4) an estimate... Department (such as the establishment of new or combination of existing organization units within a field...

Exchange Sex Among Persons Who Inject Drugs in the New York Metropolitan Area: The Importance of Local Context, Gender and Sexual Identity.

Science.gov (United States)

Walters, Suzan M; Rivera, Alexis V; Reilly, Kathleen H; Anderson, Bridget J; Bolden, Barbara; Wogayehu, Afework; Neaigus, Alan; Braunstein, Sarah

2018-02-21

Exchanging sex for money or drugs is known to increase risk for HIV among persons who inject drugs (PWID). To better understand determinants of exchange sex among PWID we examined factors associated with exchange sex in the New York metropolitan area-defined as New York City (NYC), NY; Newark, NJ; and Long Island, NY-using data from the 2012 National HIV Behavioral Surveillance system cycle on injection drug use. Of the 1160 PWID in this analysis, 24% reported exchange sex, with differences in gender and sexual identity by location. In multivariable analysis gay/bisexual men, heterosexual women, and lesbian, gay, or bisexual (LGB) women were more likely to exchange sex compared to heterosexual men. Exchange sex was also associated with race/ethnicity, homelessness, incarceration, location, and non-injection crack and cocaine use. We find that heterosexual women and LGB women who injected drugs residing in Newark were more likely to report exchange sex compared to NYC. This study highlights how local conditions impact exchange sex.

Atmospheric Research in Ny-Aalesund. Proceedings from the Third NySMAC meeting. NILU, Kjeller, Norway, 9.-11. April 1997

Energy Technology Data Exchange (ETDEWEB)

Floeisand, Inga; Gernandt, Hartwig; Larsen, Elisabeth Stoltz; Stordal, Frode; Wada, Makoto

1997-07-01

Leading abstract. The Ny-Aalesund Seminar Series was conceived by NySMAC (Ny-Aalesund Science Managers Committee) as a means of bringing together research scientists involved in programmes running at Ny-Aalesund or having an interest in that area. The first Seminar was held in Potsdam in Germany in May 1995, and included talks which covered all current research disciplines; physical, atmospheric, earth and biological sciences. The Second Seminar was devoted to biological science and particularly to ecology. It was held in Cambridge in UK in February 1996. The subject of this Third Seminar, held in Kjeller in Norway in April 1997, is atmospheric research in Ny-Aalesund. Since the early 1980s a wide range of projects have been carried out on Svalbard and particularly at Ny-Aalesund. Prominent in this research have been several international research programmes with emphasis on topics of e.g. Arctic (Arctic Monitoring and Assessment Programme, AMAP), European (European Monitoring and Evaluation Programme, EMEP) or global (International Geosphere-Biosphere Programme, IGBP; World Climate Research Programme, WCRP) scales. Atmospheric observations have been carried out in Ny-Aalesund in Svalbard for several years. From the early 1980s, the long range transport of sulphur dioxide and sulphate aerosols leading to Arctic Haze, has been studied. As a consequence, EMEP included Ny-Aalesund in their network. In the following years the transport of ozone and chemical precursors were observed, and recently the naturally occurring phenomenon of rapid surface ozone loss has been given particular attention. From the late 1980s observations of the stratospheric ozone layer and related chemical species were undertaken, and the efforts have increased considerably since. Ny-Aalesund is now one of the primary Arctic sites of the NDSC (Network for Detection of Stratospheric Change) network. Important efforts have been undertaken to participate in the European campaigns as the European

Inspiration fra NY-times

DEFF Research Database (Denmark)

Ejersbo, Lisser Rye

2015-01-01

NY-times har en ugentlig klumme med gode råd. For nogle uger siden var ugens inspiration henvendt til lærere/undervisere og drejede sig om, hvordan man skaber taletid til alle uden at have favoritter og overse de mere stille elever.......NY-times har en ugentlig klumme med gode råd. For nogle uger siden var ugens inspiration henvendt til lærere/undervisere og drejede sig om, hvordan man skaber taletid til alle uden at have favoritter og overse de mere stille elever....

American Fisheries Society 136th Annual Meeting Lake Placid, NY 10-14 September, 2006

Science.gov (United States)

Einhouse, D.; Walsh, M.G.; Keeler, S.; Long, J.M.

2005-01-01

The New York Chapter of the American Fisheries Society and the New York State Department of Environmental Conservation invite you to experience the beauty of New York's famous Adirondack Park as the American Fisheries Society (AFS) convenes its 136th Annual Meeting in the legendary Olympic Village of Lake Placid, NY, 10-14 September 2006. Our meeting theme "Fish in the Balance" will explore the interrelation between fish, aquatic habitats, and man, highlighting the challenges facing aquatic resource professionals and the methods that have been employed to resolve conflicts between those that use or have an interest in our aquatic resources. As fragile as it is beautiful, the Adirondack Region is the perfect location to explore this theme. Bordered by Mirror Lake and its namesake, Lake Placid, the Village of Lake Placid has small town charm, but all of the conveniences that a big city would provide. Whether its reliving the magic of the 1980 hockey team's "Miracle on Ice" at the Lake Placid Olympic Center, getting a panoramic view of the Adirondack high peaks from the top of the 90 meter ski jumps, fishing or kayaking in adjacent Mirror Lake, hiking a mountain trail, or enjoying a quiet dinner or shopping excursion in the various shops and restaurants that line Main Street, Lake Placid has something for everyone.

NY-BR-1 Antigen Expression and anti-NY-BR-1 IgG in Egyptian Breast Cancer Patients: Clinicopathological and Prognostic Significance.

Science.gov (United States)

Abu El-Nazar, Salma Y; Ghazy, Amany A; Ghoneim, Hossam E; Zoheir, Malak; Ahmed, Ahmed S; Sorour, Sally S; Abouelella, Amira M

2015-01-01

Breast cancer is the most common gynecological malignancy in the world. In Egypt, it ranks the first among female malignancies with incidence of 37.7%. Over the last decades, the integration of prognostic and predictive markers in treatment decisions has led to more individualized and optimized therapy. NY-BR-1 antigen has been shown to be frequently expressed in breast cancers. The study aimed to assess the tissue expression of NY-BR-1 antigen and serum IgG antibody to this antigen in Egyptian breast cancer females. The study was conducted on 60 females (10 healthy, 10 having benign breast lesions, 40 with malignant breast cancer). NY-BR-1 Ag expression was evaluated by immunohistochemistry and anti-NY-BR-1 IgG was assessed by ELISA. Results revealed a significant difference in NY-BR-1 Ag expression between benign and malignant breast cancer patients. There was a significant correlation between NY-BR-1 antigen expression and estrogen receptor's status (P = 0.019), stage of the disease (P = 0.008), menopausal status (P = 0.008), lymph node involvement (P = 0.022) and anti-NY-BR-1 IgG (P = 0.032) among the studied individuals. In addition, there was a statistically significant increase in anti-NY-BR-1 IgG O.D. results among malignant breast cancer group. It is correlated with tumor type (P < 0.001) and progesterone receptor status (P = 0.038). In conclusion, our work may represent a step towards identification of a new prognostic marker specific for breast cancer.

Parkinson's Disease Videos

Medline Plus

Full Text Available ... Miami, FL 33131 NY: 1359 Broadway, Suite 1509, New York, NY 10018 contact@parkinson.org Press Room Ask ... Miami, FL 33131 NY: 1359 Broadway, Suite 1509, New York, NY 10018 contact@parkinson.org

Concentrations of hormones, pharmaceuticals and other micropollutants in groundwater affected by septic systems in New England and New York

Science.gov (United States)

Phillips, Patrick J.; Schubert, Christopher E.; Argue, Denise M.; Fisher, Irene J.; Furlong, Edward T.; Foreman, William T.; Gray, James L.; Chalmers, Ann T.

2015-01-01

Septic-system discharges can be an important source of micropollutants (including pharmaceuticals and endocrine active compounds) to adjacent groundwater and surface water systems. Groundwater samples were collected from well networks tapping glacial till in New England (NE) and sandy surficial aquifer New York (NY) during one sampling round in 2011. The NE network assesses the effect of a single large septic system that receives discharge from an extended health care facility for the elderly. The NY network assesses the effect of many small septic systems used seasonally on a densely populated portion of Fire Island. The data collected from these two networks indicate that hydrogeologic and demographic factors affect micropollutant concentrations in these systems.

Comparative efficacy of alemtuzumab and established treatment in the management of multiple sclerosis

Directory of Open Access Journals (Sweden)

Babij R

2015-05-01

Full Text Available Rachel Babij, Jai S Perumal Department of Neurology, Weill Cornell Medical College, New York, NY, USA Abstract: Alemtuzumab is the newest disease-modifying therapy approved for the treatment of relapsing multiple sclerosis. Alemtuzumab is an anti-CD52 targeted antibody that causes lysis of T and B lymphocytes, monocytes, natural killer cells, macrophages, and dendritic cells. Following its administration, a prolonged T-cell lymphopenia results with emergence of a reconstituted immune system that differs in its composition from that pretreatment. In clinical trials, alemtuzumab has shown impressive efficacy with regard to clinical and radiological outcomes in relapsing multiple sclerosis, along with sustained long-term beneficial effects, and it is attractive for its once-yearly administration. Despite this, the occurrence of serious secondary autoimmune disorders, infections, and a potential risk of malignancy necessitates a careful evaluation of risks versus benefits for an individual patient prior to its use. The requirement of patient commitment to the intense mandatory monitoring program is also a factor to be considered when incorporating alemtuzumab into the treatment regimen. Keywords: alemtuzumab, multiple sclerosis, comparative efficacy

Geothermal energy and district heating in Ny-Ålesund, Svalbard

OpenAIRE

Iversen, Julianne

2013-01-01

This thesis presents the possibilities for using shallow geothermal energy for heating purposes in Ny-Ålesund. The current energy supply in Ny-Ålesund is a diesel generator, which does not comply with the Norwegian government and Ny-Ålesund Science Managers Committee’s common goal to maintain the natural environment in Ny-Ålesund. Ny-Ålesund has a potential for replacing the heat from the current diesel based energy source with geothermal energy. Geothermal energy is considered to have low im...

The Validity of the New York Radiological Grading Criteria in Diagnosing Sacroiliitis by Computed Tomography

Energy Technology Data Exchange (ETDEWEB)

Geijer, M.; Gadeholt Goethlin, G.; Goethlin, J.H. (Dept. of Diagnostic Radiology, Sahlgrenska Univ. Hospital, Goeteborg (Sweden))

2009-07-15

Background: Sacroiliitis in ankylosing spondylitis has frequently been graded radiographically using the New York (NY) criteria, which also have been applied in computed tomography (CT). Purpose: To validate the grading of the NY criteria in CT of the sacroiliac joints. Material and Methods: With the aid of the NY criteria, assessment of inflammatory and degenerative changes was made in 1304 CT studies. Assessment included erosions, the distribution, type, and width of sclerosis, and the involvement of the joints in sacroiliitis, as well as of normal anatomic variants such as joint space width and shape. Results: There was definite radiological sacroiliitis in 420 joints in 251 patients. Among these, more than two-thirds of the joint was involved in 71.0% of the affected joints. Sclerosis of the ilium was much more prevalent than sacral sclerosis. With increasing NY grade, iliac sclerosis, width, and extent increased, transition from sclerosis to normal bone became indistinct, and the structure of sclerosis was more inhomogeneous. Erosions of the joint surfaces were localized predominantly on the iliac side. Conclusion: Only erosions seem to be a valid solitary diagnostic sign. Solitary erosions need supplemental evidence from other inflammatory signs. Inflammatory sclerosis may be distinguished from degenerative sclerosis, and can sometimes support early diagnosis. Joint space width, joint shape, bone mineral content, or enthesopathy have no place in sacroiliitis diagnosis on CT. The NY criteria are not ideal for use with CT. A practical classification of sacroiliitis on CT is proposed, with a grading of no disease, suspected disease, and definite disease

Development of the breastfeeding quality improvement in hospitals learning collaborative in New York state.

Science.gov (United States)

Fitzpatrick, Eileen; Dennison, Barbara A; Welge, Sara Bonam; Hisgen, Stephanie; Boyce, Patricia Simino; Waniewski, Patricia A

2013-06-01

Exclusive breastfeeding is a public health priority. A strong body of evidence links maternity care practices, based on the Ten Steps to Successful Breastfeeding, to increased breastfeeding initiation, duration and exclusivity. Despite having written breastfeeding policies, New York (NY) hospitals vary widely in reported maternity care practices and in prevalence rates of breastfeeding, especially exclusive breastfeeding, during the birth hospitalization. To improve hospital maternity care practices, breastfeeding support, and the percentage of infants exclusively breastfeeding, the NY State Department of Health developed the Breastfeeding Quality Improvement in Hospitals (BQIH) Learning Collaborative. The BQIH Learning Collaborative was the first to use the Institute for Health Care Improvement's Breakthrough Series methodology to specifically focus on increasing hospital breastfeeding support. The evidence-based maternity care practices from the Ten Steps to Successful Breastfeeding provided the basis for the Change Package and Data Measurement Plan. The present article describes the development of the BQIH Learning Collaborative. The engagement of breastfeeding experts, partners, and stakeholders in refining the Learning Collaborative design and content, in defining the strategies and interventions (Change Package) that drive hospital systems change, and in developing the Data Measurement Plan to assess progress in meeting the Learning Collaborative goals and hospital aims is illustrated. The BQIH Learning Collaborative is a model program that was implemented in a group of NY hospitals with plans to spread to additional hospitals in NY and across the country.

Misuse of prescription and illicit drugs among high-risk young adults in Los Angeles and New York

Directory of Open Access Journals (Sweden)

Stephen E. Lankenau

2012-02-01

Full Text Available Background. Prescription drug misuse among young adults is increasingly viewed as a public health concern, yet most research has focused on student populations and excluded high-risk groups. Furthermore, research on populations who report recent prescription drug misuse is limited. This study examined patterns of prescription drug misuse among high-risk young adults in Los Angeles (LA and New York (NY, which represent different local markets for illicit and prescription drugs. Design and Methods. Between 2009 and 2011, 596 young adults (16 to 25 years old who had misused prescription drugs within the past 90 days were interviewed in Los Angeles and New York. Sampling was stratified to enroll three groups of high-risk young adults: injection drug users (IDUs; homeless persons; and polydrug users. Results. In both sites, lifetime history of receiving a prescription for an opioid, tranquilizer, or stimulant was high and commonly preceded misuse. Moreover, initiation of opioids occurred before heroin and initiation of prescription stimulants happened prior to illicit stimulants. NY participants more frequently misused oxycodone, heroin, and cocaine, and LA participants more frequently misused codeine, marijuana, and methamphetamine. Combining prescription and illicit drugs during drug using events was commonly reported in both sites. Opioids and tranquilizers were used as substitutes for other drugs, e.g., heroin, when these drugs were not available. Conclusion. Patterns of drug use among high-risk young adults in Los Angeles and New York appear to be linked to differences in local markets in each city for illicit drugs and diverted prescription drugs.

Dissolved methane in New York groundwater, 1999-2011

Science.gov (United States)

Kappel, William M.; Nystrom, Elizabeth A.

2012-01-01

New York State is underlain by numerous bedrock formations of Cambrian to Devonian age that produce natural gas and to a lesser extent oil. The first commercial gas well in the United States was dug in the early 1820s in Fredonia, south of Buffalo, New York, and produced methane from Devonian-age black shale. Methane naturally discharges to the land surface at some locations in New York. At Chestnut Ridge County Park in Erie County, just south of Buffalo, N.Y., several surface seeps of natural gas occur from Devonian black shale, including one behind a waterfall. Methane occurs locally in the groundwater of New York; as a result, it may be present in drinking-water wells, in the water produced from those wells, and in the associated water-supply systems (Eltschlager and others, 2001). The natural gas in low-permeability bedrock formations has not been accessible by traditional extraction techniques, which have been used to tap more permeable sandstone and carbonate bedrock reservoirs. However, newly developed techniques involving horizontal drilling and high-volume hydraulic fracturing have made it possible to extract previously inaccessible natural gas from low-permeability bedrock such as the Marcellus and Utica Shales. The use of hydraulic fracturing to release natural gas from these shale formations has raised concerns with water-well owners and water-resource managers across the Marcellus and Utica Shale region (West Virginia, Pennsylvania, New York and parts of several other adjoining States). Molofsky and others (2011) documented the widespread natural occurrence of methane in drinking-water wells in Susquehanna County, Pennsylvania. In the same county, Osborn and others (2011) identified elevated methane concentrations in selected drinking-water wells in the vicinity of Marcellus gas-development activities, although pre-development samples were not available for comparison. In order to manage water resources in areas of gas-well drilling and hydraulic

Association between assisted reproductive technology and advanced retinopathy of prematurity

Directory of Open Access Journals (Sweden)

RV Paul Chan

2010-11-01

Full Text Available RV Paul Chan1, Yoshihiro Yonekawa1, Margaux A Morrison2,3, Grace Sun1, Ryan K Wong1, Jeffrey M Perlman4, Michael F Chiang5,6, Thomas C Lee7, M Elizabeth Hartnett3, Margaret M DeAngelis2,31Department of Ophthalmology, Weill Cornell Medical College, New York; 2Ocular Molecular Genetics Institute, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts; 3University of Utah School of Medicine, Moran Eye Center, Salt Lake City, Utah; 4Department of Pediatrics, Weill Cornell Medical College, New York; Departments of 5Ophthalmology and 6Biomedical Informatics, Columbia University College of Physicians and Surgeons, New York; 7The Vision Center, Children’s Hospital Los Angeles, California, USAPurpose: To investigate the associations between assisted reproductive technology (ART and severe retinopathy of prematurity (ROP requiring treatment. Methods: Retrospective analyses of inborn preterm infants screened for severe ROP at the Weill Cornell Medical Center Neonatal Intensive Care Unit at the New York-Presbyterian Hospital by single factor logistic regression and multifactor models.Results: Of 399 ethnically diverse infants, 253 were conceived naturally and 146 by ART. Eight (3.16% patients conceived naturally, and 11 (7.53% with ART required laser treatment. In multifactor analyses, significant risks for severe ROP requiring treatment included both gestational age (odds ratio [OR] 0.34; 95% confidence interval [CI] 0.23–0.52; P< 0.001 and ART ([OR] 4.70; [CI], 1.52–4.57; P = 0.007.Conclusions: ART is associated with severe ROP requiring treatment in this cohort. This is the first report that demonstrates a statistically significant association between ART and severe ROP requiring treatment in infants in the US.Keywords: retinopathy of prematurity, low birth rate, blindness, assisted reproductive technology

Central and Peripheral Mechanisms of Antipsychotic Medication-Induced Metabolic Dysregulation

Science.gov (United States)

2016-10-01

may also significantly contribute to our fundamental understanding of obesity and lead to novel treatments. Since APD-induced metabolic disturbances...York, NY 10032 Department of Psychology , Yeshiva University, New York, NY 10016 Sponsor: Jonathan A. Javitch Background: Antipsychotic drugs...Zachary Freyberg Departments of Psychiatry, Pharmacology & Medicine, Columbia University, New York, NY 10032 Department of Psychology , Yeshiva

Vaccination with NY-ESO-1 overlapping peptides mixed with Picibanil OK-432 and montanide ISA-51 in patients with cancers expressing the NY-ESO-1 antigen.

Science.gov (United States)

Wada, Hisashi; Isobe, Midori; Kakimi, Kazuhiro; Mizote, Yu; Eikawa, Shingo; Sato, Eiichi; Takigawa, Nagio; Kiura, Katsuyuki; Tsuji, Kazuhide; Iwatsuki, Keiji; Yamasaki, Makoto; Miyata, Hiroshi; Matsushita, Hirokazu; Udono, Heiichiro; Seto, Yasuyuki; Yamada, Kazuhiro; Nishikawa, Hiroyoshi; Pan, Linda; Venhaus, Ralph; Oka, Mikio; Doki, Yuichiro; Nakayama, Eiichi

2014-01-01

We conducted a clinical trial of an NY-ESO-1 cancer vaccine using 4 synthetic overlapping long peptides (OLP; peptides #1, 79-108; #2, 100-129; #3, 121-150; and #4, 142-173) that include a highly immunogenic region of the NY-ESO-1 molecule. Nine patients were immunized with 0.25 mg each of three 30-mer and a 32-mer long NY-ESO-1 OLP mixed with 0.2 KE Picibanil OK-432 and 1.25 mL Montanide ISA-51. The primary endpoints of this study were safety and NY-ESO-1 immune responses. Five to 18 injections of the NY-ESO-1 OLP vaccine were well tolerated. Vaccine-related adverse events observed were fever and injection site reaction (grade 1 and 2). Two patients showed stable disease after vaccination. An NY-ESO-1-specific humoral immune response was observed in all patients and an antibody against peptide #3 (121-150) was detected firstly and strongly after vaccination. NY-ESO-1 CD4 and CD8 T-cell responses were elicited in these patients and their epitopes were identified. Using a multifunctional cytokine assay, the number of single or double cytokine-producing cells was increased in NY-ESO-1-specific CD4 and CD8 T cells after vaccination. Multiple cytokine-producing cells were observed in PD-1 (-) and PD-1 (+) CD4 T cells. In conclusion, our study indicated that the NY-ESO-1 OLP vaccine mixed with Picibanil OK-432 and Montanide ISA-51 was well tolerated and elicited NY-ESO-1-specific humoral and CD4 and CD8 T-cell responses in immunized patients.

Urban metabolism in Syracuse, NY – introduction

Science.gov (United States)

David J. Nowak

2016-01-01

This special issue of Urban Ecosystems contains a series of papers related to assessing urban metabolism in Syracuse, NY. These papers were developed under the Urban Long-Term Research Area Exploratory Awards Program funded by the National Science Foundation. Objectives of this two-year project (2009–2011) in Syracuse, NY were to investigate: a)...

Urban Bikescapes in New York

DEFF Research Database (Denmark)

Marling, Gitte

Urban Bike Scapes in New Yo rk af Gitte Marling Aalborg Universitet, maj 2013 - Mapping af arkitektur, byrum og byliv Urban Bike Scapes in New York Et ‘urbant bike scape’ er en ny urban arkitektonisk typologi, der repræsenterer en designmæssig sammentænkning af et mobilitetsrum i form af en cykelog......, etniske og livsstilsmæssige baggrunde. De fungerer på forskellig vis som open minded offentlige mødesteder og som public domains. Urban Bike Scapes giver nye byoplevelser, fordi der i designet er arbejdet med at skabe arkitektur og bylandskaber med store æstetiske kvaliteter i form af skiftende rytme......, belægninger, rumligheder, skala og materialer. Der er tale om performativ eller haptisk arkitektur, der taler til sanser, følelser og refleksion, og som er skabt med det formål at styrke kroppen og kropslig udfoldelse. ‘Urban Bike Scapes in New York’ er en byarkitektonisk mapping af det nye cykelmiljø, som i...

33 CFR 110.8 - Lake Champlain, N.Y. and Vt.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lake Champlain, N.Y. and Vt. 110... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.8 Lake Champlain, N.Y. and Vt. (a) Ticonderoga, N.Y. An area shoreward of a line bearing 312° from Ticonderoga Light to the southeast corner of the...

Ny rapport advarer

DEFF Research Database (Denmark)

Jex, Catherine; Seidenkrantz, Marit-Solveig; Colgan, William

2017-01-01

Ifølge forskerne bag en ny mellemstatslig rapport vil den globale opvarmning få endnu flere og meget drastiske konsekvenser for det arktiske klima end hidtil antaget. Men klimaaftalen fra Paris kan afværge nogle af de største forandringer efter år 2050. Hvis den bliver implementeret øjeblikkeligt...

33 CFR 110.208 - Buffalo Harbor, N.Y.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Buffalo Harbor, N.Y. 110.208 Section 110.208 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.208 Buffalo Harbor, N.Y. (a) The anchorage grounds—(1...

Solar Market Analytics, Roadmapping, and Tracking NY (SMART NY) Final Report

Energy Technology Data Exchange (ETDEWEB)

Case, Tria [City University of New York; Reilly, Laurie [City University of New York; Kling, Alison [Con Edison, formerly City University of New York

2014-05-15

This is the final report, including links to Working Group reports and an attached Working Group report for SunShot Initiative Rooftop Solar Challenge I, from Sustainable CUNY of the City University of New York, on behalf of New York City

Leadership Principles Leveraged from Key Civil War Battles

Science.gov (United States)

2017-05-15

war answer book . Canton, MI: Visible Ink Press. Foote, S. (1994). Stars in their courses: the Gettysburg campaign june-july 1863. New York , NY... York , NY: Ballantine Books . Shaara, M. (1975). The killer angels. New York , NY: Random House Publishing Group. Snow D.M. & Drew D.M. (2015). From...pertinent data from books , journals, periodicals, and videos in this area of leadership research. The review of literature will entail analyzing

Differences in Awareness of Pre-exposure Prophylaxis and Post-exposure Prophylaxis Among Groups At-Risk for HIV in New York State: New York City and Long Island, NY, 2011-2013.

Science.gov (United States)

Walters, Suzan M; Rivera, Alexis V; Starbuck, Lila; Reilly, Kathleen H; Boldon, Nyasha; Anderson, Bridget J; Braunstein, Sarah

2017-07-01

Pre-exposure prophylaxis (PrEP) to reduce the risk of HIV was approved in 2012 and post-exposure prophylaxis (PEP) in 2005. We report the differences in awareness of PrEP/PEP and factors associated with awareness by examining 3 risk groups (men who have sex with men (MSM), people who inject drugs, and high-risk heterosexuals). National HIV Behavioral Surveillance system data collected in New York City (NYC) and Long Island, NY in 2011-2013 were used. Logistic regressions by region were developed to estimate adjusted associations [Adjusted Odds Ratios (AOR)] and determine differences in awareness of PrEP/PEP. Awareness of PrEP/PEP was low for all groups. In multivariate analysis controlling for sociodemographic factors, noninjection drug use, HIV status, and exposure to HIV prevention, males who inject drugs in NYC had significantly decreased odds of PrEP/PEP awareness [AOR: 0.45; confidence interval (CI): 0.25 to 0.81] compared with MSM. MSM aged 18-29 years had increased awareness of PrEP (AOR: 2.94; 95% CI 1.11 to 7.80). On Long Island, females who inject drugs (AOR: 0.18; 95% CI: 0.05 to 0.62), males who inject drugs (AOR: 0.14; 95% CI: 0.05 to 0.39), female heterosexuals (AOR: 0.25; 95% CI: 0.11 to 0.59), and male heterosexuals (AOR: 0.32; 95% CI: 0.14 to 0.73) had significantly decreased odds of PrEP/PEP awareness. Black MSM had increased awareness of PrEP (AOR: 4.08 CI:1.21 to 13.73). Large proportions of groups at-risk for HIV were unaware of PrEP/PEP. When comparing risk groups to MSM, we found MSM to have greater awareness in both regions. On Long Island, people who inject drugs and heterosexuals were far less likely to have PrEP/PEP awareness than in NYC. On Long Island, Black MSM had increased PrEP awareness and in NYC MSM aged 18-29 had increased PrEP awareness. These findings suggest that awareness may be spreading through networks and highlight the importance of targeted educational and prevention efforts by group and region.

Can Future Academic Surgeons be Identified in the Residency Ranking Process?

Science.gov (United States)

Beninato, Toni; Kleiman, David A; Zarnegar, Rasa; Fahey, Thomas J

2016-01-01

The goal of surgical residency training programs is to train competent surgeons. Academic surgical training programs also have as a mission training future academicians-surgical scientists, teachers, and leaders. However, selection of surgical residents is dependent on a relatively unscientific process. Here we sought to determine how well the residency selection process is able to identify future academicians in surgery. Rank lists from an academic surgical residency program from 1992 to 1997 were examined. All ranked candidates׳ career paths after residency were reviewed to determine whether they stayed in academics, were university affiliated, or in private practice. The study was performed at New York Presbyterian Hospital-Weill Cornell Medical College, New York, NY. A total of 663 applicants for general surgery residency participated in this study. In total 6 rank lists were evaluated, which included 663 candidates. Overall 76% remained in a general surgery subspecialty. Of those who remained in general surgery, 49% were in private practice, 20% were university affiliated, and 31% had academic careers. Approximately 47% of candidates that were ranked in the top 20 had ≥20 publications, with decreasing percentages as rank number increased. There was a strong correlation between the candidates׳ rank position and pursuing an academic career (p career. The residency selection process can identify candidates likely to be future academicians. Copyright © 2016 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

77 FR 49783 - Procurement List; Additions

Science.gov (United States)

2012-08-17

...), Office of the Principal Legal Advisor, New York Office of Chief Counsel, 290 Broadway Street, New York, NY NPA: Fedcap Rehabilitation Services, Inc., New York, NY Contracting Activity: Dept of Homeland... ``E'' Street, Buildings 59 & 79 Magazine Road, Portsmouth, VA Washington Navy Yard, 1325 10th Street...

33 CFR 110.84b - Buffalo, N.Y.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Buffalo, N.Y. 110.84b Section 110... REGULATIONS Special Anchorage Areas § 110.84b Buffalo, N.Y. The area within the Port of Buffalo known as Port of Buffalo Small Boat Harbor commencing at a point on shore at latitude 42°51′05″ N., longitude 78°51...

New York Household Travel Patterns: A Comparison Analysis

Energy Technology Data Exchange (ETDEWEB)

Hu, Patricia S [ORNL; Reuscher, Tim [ORNL

2007-05-01

In 1969, the U. S. Department of Transportation began collecting detailed data on personal travel to address various transportation planning issues. These issues range from assessing transportation investment programs to developing new technologies to alleviate congestion. This 1969 survey was the birth of the Nationwide Personal Transportation Survey (NPTS). The survey was conducted again in 1977, 1983, 1990 and 1995. Longer-distance travel was collected in 1977 and 1995. In 2001, the survey was renamed to the National Household Travel Survey (NHTS) and collected both daily and longer-distance trips in one survey. In addition to the number of sample households that the national NPTS/NHTS survey allotted to New York State (NYS), the state procured an additional sample of households in both the 1995 and 2001 surveys. In the 1995 survey, NYS procured an addition sample of more than 9,000 households, increasing the final NY NPTS sample size to a total of 11,004 households. Again in 2001, NYS procured 12,000 additional sample households, increasing the final New York NHTS sample size to a total of 13,423 households with usable data. These additional sample households allowed NYS to address transportation planning issues pertinent to geographic areas significantly smaller than for what the national NPTS and NHTS data are intended. Specifically, these larger sample sizes enable detailed analysis of twelve individual Metropolitan Planning Organizations (MPOs). Furthermore, they allowed NYS to address trends in travel behavior over time. In this report, travel data for the entire NYS were compared to those of the rest of the country with respect to personal travel behavior and key travel determinants. The influence of New York City (NYC) data on the comparisons of the state of New York to the rest of the country was also examined. Moreover, the analysis examined the relationship between population density and travel patterns, and the similarities and differences among New

Deletion of Xpter encompassing the SHOX gene and PAR1 region in familial patients with Leri-Weill Dyschondrosteosis syndrome.

Science.gov (United States)

Mutesa, L; Vanbellinghen, J F; Hellin, A C; Segers, K; Jamar, M; Pierquin, G; Bours, V

2009-01-01

Heterozygote deletions or mutations of pseudoautosomal 1 region (PAR1) encompassing the short stature homeobox-containing (SHOX) gene cause Leri-Weill Dyschondrosteosis (LWD), which is a dominantly inherited osteochondroplasia characterized by short stature with mesomelic shortening of the upper and lower limbs and Madelung deformity of the wrists. SHOX is expressed by both sex chromosomes in males and females and plays an important role in bone growth and development. Clinically, the LWD expression is variable and more severe in females than males due to sex differences in oestrogen levels. Here, we report two familial cases of LWD with a large Xp terminal deletion (approximately 943 kb) of distal PAR1 encompassing the SHOX gene. In addition, the proband had mental retardation which appeared to be from recessive inheritance in the family.

A phase I study of vaccination with NY-ESO-1f peptide mixed with Picibanil OK-432 and Montanide ISA-51 in patients with cancers expressing the NY-ESO-1 antigen.

Science.gov (United States)

Kakimi, Kazuhiro; Isobe, Midori; Uenaka, Akiko; Wada, Hisashi; Sato, Eiichi; Doki, Yuichiro; Nakajima, Jun; Seto, Yasuyuki; Yamatsuji, Tomoki; Naomoto, Yoshio; Shiraishi, Kenshiro; Takigawa, Nagio; Kiura, Katsuyuki; Tsuji, Kazuhide; Iwatsuki, Keiji; Oka, Mikio; Pan, Linda; Hoffman, Eric W; Old, Lloyd J; Nakayama, Eiichi

2011-12-15

We conducted a phase I clinical trial of a cancer vaccine using a 20-mer NY-ESO-1f peptide (NY-ESO-1 91-110) that includes multiple epitopes recognized by antibodies, and CD4 and CD8 T cells. Ten patients were immunized with 600 μg of NY-ESO-1f peptide mixed with 0.2 KE Picibanil OK-432 and 1.25 ml Montanide ISA-51. Primary end points of the study were safety and immune response. Subcutaneous injection of the NY-ESO-1f peptide vaccine was well tolerated. Vaccine-related adverse events observed were fever (Grade 1), injection-site reaction (Grade 1 or 2) and induration (Grade 2). Vaccination with the NY-ESO-1f peptide resulted in an increase or induction of NY-ESO-1 antibody responses in nine of ten patients. The sera reacted with recombinant NY-ESO-1 whole protein as well as the NY-ESO-1f peptide. An increase in CD4 and CD8 T cell responses was observed in nine of ten patients. Vaccine-induced CD4 and CD8 T cells responded to NY-ESO-1 91-108 in all patients with various HLA types with a less frequent response to neighboring peptides. The findings indicate that the 20-mer NY-ESO-1f peptide includes multiple epitopes recognized by CD4 and CD8 T cells with distinct specificity. Of ten patients, two with lung cancer and one with esophageal cancer showed stable disease. Our study shows that the NY-ESO-1f peptide vaccine was well tolerated and elicited humoral, CD4 and CD8 T cell responses in immunized patients. Copyright © 2011 UICC.

Ny vaccine mod ledbetændelse er ikke effektiv

DEFF Research Database (Denmark)

Nielsen, Elisabeth Okholm; Lauritsen, Klara Tølbøll

2013-01-01

En ny mulighed for at vaccinere mod mykoplasma-ledbetændelse er undersøgt hos en slagtesvineproducent. Vaccinen kunne desværre ikke forebygge halthed eff ektivt.......En ny mulighed for at vaccinere mod mykoplasma-ledbetændelse er undersøgt hos en slagtesvineproducent. Vaccinen kunne desværre ikke forebygge halthed eff ektivt....

33 CFR 110.87 - Henderson Harbor, N.Y.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Henderson Harbor, N.Y. 110.87... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.87 Henderson Harbor, N.Y. (a) Area A. The area in the... latitude 43°51′08.8″ N, longitude 76°12′08.9″ W, thence to latitude 43°51′09.0″ N, longitude 76°12′19.0″ W...

A Leadership Competency Model for U.S. Air Force Wing Chaplains

Science.gov (United States)

2009-02-12

Daniel Goleman , Working with Emotional Intelligence (New York, NY: Bantam Books, 1998); Richard L...Competencies.” 51 Howard, “Identifying, Assessing, and Selecting Leaders.” 52 Daniel Goleman , Working with Emotional Intelligence (New York: Bantam Books...and Mechanical College, 1967. Goleman , Daniel . Working with Emotional Intelligence . New York, NY: Bantam Books, 1998. Goleman , Daniel ,

33 CFR 110.85 - Niagara River, Youngstown, N.Y.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Niagara River, Youngstown, N.Y... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.85 Niagara River, Youngstown, N.Y. (a) Area 1... of the Niagara River at latitude 43°14′33″ N, longitude 79°03′7.5″ W; thence westerly to a point at...

NILU`s Atmospheric Research at Ny-Aalesund

Energy Technology Data Exchange (ETDEWEB)

Beine, H.J.

1997-12-31

At Ny-Aalesund, Spitsbergen, NILU is involved in many scientific projects that focus on global and regional atmospheric chemistry such as stratospheric ozone depletion, the greenhouse effect (from gases and aerosols), tropospheric ozone (in-situ production and depletion in the boundary layer), or the transport of pollutants from mid-latitudes (Arctic haze). This report presents a brief historical overview of NILU`s research activities at Ny-Aalesund since 1973. It also discusses the scientific results of the first years of operation of the Zeppelin station since 1989, and presents ongoing projects. 128 refs., 20 figs., 1 table

Medline Plus

Full Text Available ... Surgery, New York, NY, 12/11/2013) Computer Guided Knee Replacement (Broward Health North Medical Center, Deerfield ... Surgery, New York, NY, 12/11/2013) Computer Guided Knee Replacement (Broward Health North Medical Center, Deerfield ...

Medline Plus

Full Text Available ... Special Surgery, New York, NY, 12/11/2013) Computer Guided Knee Replacement (Broward Health North Medical Center, ... Special Surgery, New York, NY, 12/11/2013) Computer Guided Knee Replacement (Broward Health North Medical Center, ...

Medline Plus

Full Text Available ... Cruciate Stabilized (BCS) Total Knee System (Hospital for Special Surgery, New York, NY, 12/11/2013) Computer ... Cruciate Stabilized (BCS) Total Knee System (Hospital for Special Surgery, New York, NY, 12/11/2013) Computer ...

Medline Plus

Full Text Available ... 5/08/2008) Testicular Disorders Varicocele Surgery (Beth Israel Medical Center, New York, NY, 2/24/2009) ... Reconstruction Breast Reconstruction: Deep Inferior Epigastric Perforator (Beth Israel Medical Center, New York, NY, 1/11/2008) ...

Initial colonization of Long Island, New York by the eastern coyote, Canis latrans (Carnivora, Canidae), including first record of breeding

OpenAIRE

Nagy,Christopher; Weckel,Mark; Monzón,Javier; Duncan,Neil; Rosenthal,Michael R.

2017-01-01

Coyotes (Canis latrans Say, 1823) have increased their range dramatically over the past century. Formerly restricted to western North America, they now roam across the continent, in many habitats including large cities. One of the last areas in North America without coyotes has been Long Island, NY, a 3629 km2 island in the New York metropolitan area. Here we summarize all verified accounts of coyotes on Long Island, including the first record of breeding. There are few coyotes on Long Islan...

77 FR 22530 - Safety Zone; Fireworks, Hudson River, Rhinecliff, NY

Science.gov (United States)

2012-04-16

...-AA00 Safety Zone; Fireworks, Hudson River, Rhinecliff, NY AGENCY: Coast Guard, DHS. ACTION: Notice of... navigable waters of the Hudson River in the vicinity of Rhinecliff, NY for a fireworks display. This... fireworks displays. This rule is intended to restrict all vessels from a portion of the Hudson River before...

Medline Plus

Full Text Available ... to Treat Obstructive Hypertrophic Cardiomyopathy (HCM) (Roosevelt Hospital, New York, NY, 1/04/2012) Coronary Artery Disease Transradial ... Heart Failure Surgical Ventricular Reconstruction (Montefiore Medical Center, New York, NY, 2/13/2008) Heart Health Tests Transesophageal ...

33 CFR 207.60 - Federal Dam, Hudson River, Troy, N.Y.; pool level.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Federal Dam, Hudson River, Troy, N.Y.; pool level. 207.60 Section 207.60 Navigation and Navigable Waters CORPS OF ENGINEERS..., N.Y.; pool level. (a) Whenever the elevation of the pool created by the Federal dam at Troy, N.Y...

Quantifying Microplastic Pollution in the Mohawk River, Eastern New York State

Science.gov (United States)

Smith, J. A.; Hodge, J.; Kurtz, B. G.; Garver, J. I.

2016-12-01

We are investigating the extent to which microplastic particles are reaching the Mohawk River in upstate New York. Microplastics are commonly defined as plastic particles less than 5 mm in diameter, whether deliberately manufactured to be that size or resulting from the fragmentation or erosion of larger pieces of plastic. Despite recent legislative bans, many personal care products such as facial scrubs still use tiny particles of plastic as abrasives. Plastic fibers also make up part of the microplastic load potentially reaching waterways. Microplastic particles are a health hazard for aquatic organisms and an undesirable component of public water supplies. The Mohawk River is the main tributary of the Hudson River, coinciding with the Erie Canal for stretches downriver from Rome, NY, and serves as both the outfall for wastewater treatment plants and the water supply for several municipalities. In some cities along the Mohawk River (e.g., Utica, NY), combined sewer overflows (CSOs) deliver untreated sewage and stormwater directly to the river during heavy rainfall events, increasing the likelihood of microplastic pollution. We used a manta trawl deployed from a rigid inflatable boat to collect 60 samples of planktonic material along the 112-mile section of the Mohawk River and/or Erie Canal between Rome, NY, and the Crescent Dam in Cohoes, NY. Each trawl lasted for 1 mile. We used an Ekman grab sampler to collect 64 samples of channel sediment along the same section of the Mohawk River and/or Erie Canal. Sample processing for planktonic samples includes sieving and wet peroxide oxidation to remove organic material. Sample processing for sediment grab samples includes drying, sieving, density separation, and wet peroxide oxidation. Anthropogenic particles that contain dye are easiest to spot under a microscope. Laboratory analyses indicate that the majority of the planktonic samples include dyed particles in addition to colorless particles likely to be plastic

33 CFR 110.150 - Block Island Sound, N.Y.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Block Island Sound, N.Y. 110.150... ANCHORAGE REGULATIONS Anchorage Grounds § 110.150 Block Island Sound, N.Y. (a) The anchorage ground. A 3/4... following coordinates: latitude 41°06′12″ N., longitude 72°00′05″ W., latitude 41°07′40″ N., longitude 72°01...

77 FR 41271 - Safety Zone; Newburgh to Beacon Swim, Newburgh, Hudson River, NY

Science.gov (United States)

2012-07-13

... 1625-AA00 Safety Zone; Newburgh to Beacon Swim, Newburgh, Hudson River, NY AGENCY: Coast Guard, DHS... navigable waters of the Hudson River, NY in the vicinity of Newburgh, NY for the annual Newburgh Beacon Swim... Beacon Swim is an annual recurring event that has a permanent safety zone found at 33 CFR 165.160. The...

Observed and Model-Derived Ozone Production Efficiency over Urban and Rural New York State

Directory of Open Access Journals (Sweden)

Matthew Ninneman

2017-07-01

Full Text Available This study examined the model-derived and observed ozone production efficiency (OPE = ∆Ox/∆NOz in one rural location, Pinnacle State Park (PSP in Addison, New York (NY, and one urban location, Queens College (QC in Flushing, NY, in New York State (NYS during photo-chemically productive hours (11 a.m.–4 p.m. Eastern Standard Time (EST in summer 2016. Measurement data and model predictions from National Oceanic and Atmospheric Administration National Air Quality Forecast Capability (NOAA NAQFC—Community Multiscale Air Quality (CMAQ model versions 4.6 (v4.6 and 5.0.2 (v5.0.2 were used to assess the OPE at both sites. CMAQ-predicted and observed OPEs were often in poor agreement at PSP and in reasonable agreement at QC, with model-predicted and observed OPEs, ranging from approximately 5–11 and 10–13, respectively, at PSP; and 4–7 and 6–8, respectively, at QC. The observed relationship between OPE and oxides of nitrogen (NOx was studied at PSP to examine where the OPE downturn may have occurred. Summer 2016 observations at PSP did not reveal a distinct OPE downturn, but they did indicate that the OPE at PSP remained high (10 or greater regardless of the [NOx] level. The observed OPEs at QC were found by using species-specific reactive odd nitrogen (NOy instruments and an estimated value for nitrogen dioxide (NO2, since observed OPEs determined using non-specific NOx and NOy instruments yielded observed OPE results that (1 varied from approximately 11–25, (2 sometimes had negative [NOz] concentrations, and (3 were inconsistent with CMAQ-predicted OPE. This difference in observed OPEs at QC depending on the suite of instruments used suggests that species-specific NOx and NOy instruments may be needed to obtain reliable urban OPEs.

Ny industrialisering - et bedre produktmarked

DEFF Research Database (Denmark)

Beim, Anne

2001-01-01

for byggeriet med titlerne: 1. Bygherren som forandringsagent. 2. Tæt samarbejde i byggedelen. 3. Ny industrialisering. 4. Byg med kommunikation og innovation. Dette debathæfte er nummer tre i rækken og omhandler byggeriets industridel og mulighederne for at fremme en succesfuld industriel produktion....

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

population stratification; ancestry informative markers (AIMs); race; ethnicity; genetic epidemiology; forensic genetics; Hispanics. ... Department of Microbiology, Mount Sinai School of Medicine, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, NY 10029 ...

Increased NY-ESO-1 Expression and Reduced Infiltrating CD3+ T Cells in Cutaneous Melanoma

Directory of Open Access Journals (Sweden)

Mara Giavina-Bianchi

2015-01-01

Full Text Available NY-ESO-1 is a cancer-testis antigen aberrantly expressed in melanomas, which may serve as a robust and specific target in immunotherapy. NY-ESO-1 antigen expression, tumor features, and the immune profile of tumor infiltrating lymphocytes were assessed in primary cutaneous melanoma. NY-ESO-1 protein was detected in 20% of invasive melanomas (16/79, rarely in in situ melanoma (1/10 and not in benign nevi (0/20. Marked intratumoral heterogeneity of NY-ESO-1 protein expression was observed. NY-ESO-1 expression was associated with increased primary tumor thickness (P=0.007 and inversely correlated with superficial spreading melanoma (P<0.02. NY-ESO-1 expression was also associated with reduced numbers and density of CD3+ tumor infiltrating lymphocytes (P=0.017. When NY-ESO-1 protein was expressed, CD3+ T cells were less diffusely infiltrating the tumor and were more often arranged in small clusters (P=0.010 or as isolated cells (P=0.002 than in large clusters of more than five lymphocytes. No correlation of NY-ESO-1 expression with gender, age, tumor site, ulceration, lymph node sentinel status, or survival was observed. NY-ESO-1 expression in melanoma was associated with tumor progression, including increased tumor thickness, and with reduced tumor infiltrating lymphocytes.

Geotechnical analysis of soil samples from test trench at Western New York Nuclear Service Center, West Valley, New York

International Nuclear Information System (INIS)

Fickies, R.H.; Fakundiny, R.H.; Mosley, E.T.

1979-04-01

In July 1977, a deep research trench was excavated and soil samples collected at the Western New York Nuclear Services Center, West Valley, NY. The glacial till horizons sampled are considered to be representative of the till serving as a burial medium at the nearby low-level radioactive waste burial ground. A series of laboratory tests were conducted consisting of unit weight, moisture content, Atterberg limits, unconfined compression, dispersion, swell, permeability, and consolidation. These laboratory analyses and field observations indicate that the till exposed in the research trench is a generally dense mixture of silt and clay of low to medium plasticity, with minor amounts of fine to coarse sand and fine gravel. The till has a generally low coefficient of permeability in the range of 10 -7 cm/s horizontal and 10 -8 cm/s vertical. A network of vertical fractures exists in the upper 15 feet of weathered till which may allow some downward percolation of surface runoff. The test data indicates that the maximum depth to which these fractures could possibly penetrate is 50 feet

It is not Just a Press Conference: The Consequences of Crisis Communication While the World Watches

Science.gov (United States)

2014-03-01

Abraham H. Maslow , Motivation and Personality (New York, NY: Harper and Row, 1970). 26 THIS PAGE INTENTIONALLY LEFT BLANK 27 III. RESEARCH DESIGN...http://www.forbes.com/sites/kenmakovsky/2013/10/03/1159/. Maslow , Abraham H. Motivation and Personality. New York, NY: Harper and Row, 1970. Miles

Segmental NF: A Guide for Patients

Science.gov (United States)

... available. How can I learn more? Children’s Tumor Foundation 120 Wall Street, 16th Floor New York, NY 10005 toll ... University of Alabama at Birmingham © 2011 Children’s Tumor Foundation. All rights reserved. Reprinted 2015 120 Wall Street, 16 th Floor New York, NY 10005 ...

Blue Harvest: Evaluating Human Capital Management Policy for the 21st Century Air Force

Science.gov (United States)

2017-06-01

231 Kane, Bleeding Talent, 219. 232 Sun Tzu , The Art of War, trans. Samuel B. Griffith (New York, NY: Oxford...Economics, January 1997: 165-188. 78 Sun Tzu . The Art of War. Translated by Samuel B. Griffith. New York, NY: Oxford University Press, 1963...63 BIBLIOGRAPHY

33 CFR 110.156 - Randall Bay, Freeport, Long Island, N.Y.

Science.gov (United States)

2010-07-01

... Island, N.Y. 110.156 Section 110.156 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.156 Randall Bay, Freeport, Long Island, N.Y. (a) The anchorage grounds. Southward of a line 312 feet south of and parallel to the south side...

Udlejers godkendelse af ny erhvervslejer

DEFF Research Database (Denmark)

Munk-Hansen, Carsten

2009-01-01

I artiklen er taget udgangspunkt i den »klassiske« afståelsessituation, hvor en lejer vil afhænde den i de lejede lokaler drevne virksomhed, og lejeren har afståelsesret til en af udlejer godkendt lejer, uden at kravene til den ny lejer er specificeret. På baggrund af Vestre Landsrets dom af 9/2 ...

Water table in Long Island, New York, March 1971

Science.gov (United States)

Koszalka, Edward J.; Koch, Ellis

1971-01-01

The geologic framework and the hydrologic situation in Long Island are periodically reviewed by the U.S. Geological Survey as new knowledge is obtained from current investigations. This work is done through cooperative programs with Nassau and Suffolk County agencies and the New York State Department of Environmental Conservation. A unique opportunity to update many of the hydrogeologic maps occurred when the Geological Survey's Mineola, N.Y., office participated in the New England River Basins Commission's "Long Island Sound Study." This map, one of a series of open-file maps showing the updated information, was compiled from data obtained from G. E. Kimmel (written commun., July 1972) and Jensen and Soren (in press). Comparison of the March 1971 data with similar data for March 1970 (Kimmel, 1970) shows virtually no change in water levels on Long Island during the 12 month period, except for a slight decline in levels in central Suffolk County.

Gamification is broken. An interview with Steven Poole

Directory of Open Access Journals (Sweden)

Marco Benoit Carbone

2012-05-01

Full Text Available Steven Poole is the author of Trigger Happy (2000. New York, NY: Arcade Publish, Unspeak (2006. New York, NY: Grove Press, and You Aren’t What You Eat (2012. In press. He has written extensively on books, culture, and videogames for The Guardian and other publications.

National Dam Safety Program. Larchwood Lake Dam (Inventory Number NY 727), Susquehanna River Basin, Otsego County, New York. Phase I Inspection Report,

Science.gov (United States)

1981-08-04

8217 IELT OR BASE FLOw. USE VALUE i9?OF’ N. Y STATE NAMP - MINI/tM W’ RUNOFF (1ANm~s/DAy) FOR DEE,4-,/w,6 7W P-S/ r’ Pslic 2/6 t US5E 0. (/1IAy D-9...RESOURCES COMMISSION CONSERVATION DEPARTMENT ALBANY, N.Y. 12226 Do Not Write in This Box AppI. No. _____411_____V/ Darn No. __ __ __ __ Permit No. Watershed...extent and in such time and manner also notify him promptly in writing of the completion of the as the Water Resources Commission may require, remove

Integer programming and combinatorial optimization : 15th international conference, IPCO 2011, New York NY, USA, June 15-17, 2011 : proceedings

NARCIS (Netherlands)

Günlük, O.; Woeginger, G.J.

2011-01-01

This volume contains the 33 papers presented at IPCO 2011, the 15th Conference on Integer Programming and Combinatorial Optimization, held during June 15–17, 2011 at the IBM T.J. Watson Research Center in New York, USA. IPCO conferences are sponsored by the Mathematical Optimization Society. The

Oxidized Nitrogen Balance over 15 Months at Rural and Urban New York State Locations

Science.gov (United States)

Schwab, J. J.; Ninneman, M.; Marto, J.; Edgerton, E. S.; Blanchard, C. L.; Shaw, S. L.

2017-12-01

Continuous measurements of oxidized nitrogen species (NO, NO2, and HNO3), families of species (NOy, alkyl nitrates [or ANs], and peroxyacetyl nitrates [or PANs]), and particle nitrate (pNO3) were carried out for a fifteen-month period from August 2016 through October 2017 at two locations in New York State. The two sites were a rural research station at Pinnacle State Park in Addison, NY and an urban research station at Queens College in New York City. Four different chemiluminescence analyzers with various converters and denuders were employed to make these measurements. Instrumentation used for the study will be described, as well as some of the challenges created by combining data from these independent analyzers to address the oxidized nitrogen budget at the two sites. The Pinnacle State Park site often experiences quite clean air with low ppb levels of total NOy and a greater fraction of oxidized nitrogen products (NOz species). This contrasts with the urban Queens College location, which experiences stronger NOx sources. Seasonal differences in the NOx/NOy and NOz/NOy ratios, and the makeup of the NOz species, are also significant and will be explored in the presentation.

40 CFR 81.333 - New York.

Science.gov (United States)

2010-07-01

... Designated area Designation Date 1 Type Classification Date 1 Type Albany-Schenectady-Troy Area: Albany... Date 1 Type Albany-Schenectady-Troy, NY: Albany County Nonattainment Subpart 1. Greene County.... Albany-Schenectady-Troy, NY: Albany County Unclassifiable/Attainment. Greene County Unclassifiable...

The New York City Research Initiative: A Model for Undergraduate and High School Student Research in Earth and Space Sciences and Space Technology

Science.gov (United States)

Scalzo, F.; Frost, J.; Carlson, B. E.; Marchese, P.; Rosenzweig, C.; Austin, S. A.; Peteet, D. M.; Druyan, L.; Fulakeza, M.; Gaffin, S.; Baruh, H.; Decker, S.; Thangam, S.; Miles, J.; Moshary, F.; Rossow, W.; Greenbaum, S.; Cheung, T. K.; Johnson, L. P.

2010-12-01

1 Frank Scalzo, 1 Barbara Carlson, 2 Leon Johnson, 3 Paul Marchese, 1 Cynthia Rosenzweig, 2 Shermane Austin, 1 Dorothy Peteet, 1 Len Druyan, 1 Matthew Fulakeza, 1 Stuart Gaffin, 4 Haim Baruh, 4 Steven Decker, 5 Siva Thangam, 5 Joe Miles, 6 James Frost, 7 Fred Moshary, 7 William Rossow, 7 Samir Ahmed, 8 Steven Greenbaum and 3 Tak Cheung 1 NASA Goddard Institute for Space Studies, USA 2 Physical, Environmental and Computer Sciences, Medgar Evers College, CUNY, Brooklyn, NY, USA 3 Physics, Queensborough Community College, CUNY, Queens, NY, USA 4 Rutgers University, Newark, NJ, USA 5 Stevens Institute of Technology, Hoboken, NJ, USA 6 Physics, LaGuardia Community College, CUNY, Queens, NY, USA 7 Electrical Engineering, City College of New York, CUNY, USA 8 Physics, Hunter College, CUNY, USA The New York City Research Initiative (NYCRI) is a research and academic program that involves high school, undergraduate and graduate students, and high school teachers in research teams under the mentorship of college/university principal investigator of NASA funded projects and/or NASA scientists. The principal investigators are at 7 colleges/universities within a 20-mile radius of New York City (NYC and Northern New Jersey), as well as the NASA Goddard Institute of Space Studies. The program supports research in Earth Science, Space Science, and Space Technology. Research investigations include: Sea Surface Temperature and Precipitation in the West African Monsoon, Urban Heat Island: Sun and Rain Effects, Decadal Changes in Aerosol and Asthma, Variations in Salinity and River Discharge in the Hudson River Estuary, Environmental Change in the Hudson Estuary Wetlands, Verification of Winter Storm Scale Developed for Nor’easters, Solar Weather and Tropical Cyclone Activity, Tropospheric and Stratospheric Ozone Investigation in Metropolitan NYC, Aerosol Optical Depth through use of a MFRSR, Detection of Concentration in the Atmosphere Using a Quantum Cascade Laser System

76 FR 34865 - Safety Zone; Rochester Harbor Festival, Genesee River, Rochester, NY

Science.gov (United States)

2011-06-15

...-AA00 Safety Zone; Rochester Harbor Festival, Genesee River, Rochester, NY AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing a temporary safety zone on the Genesee River, Rochester, NY for the Rochester Harbor Festival fireworks. This zone is intended to...

33 CFR 207.580 - Buffalo Harbor, N.Y.; use, administration, and navigation.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Buffalo Harbor, N.Y.; use, administration, and navigation. 207.580 Section 207.580 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE NAVIGATION REGULATIONS § 207.580 Buffalo Harbor, N.Y.; use...

33 CFR 162.15 - Manhasset Bay, N.Y.; seaplane restricted area.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Manhasset Bay, N.Y.; seaplane... Bay, N.Y.; seaplane restricted area. (a) The restricted area. An area in Manhasset Bay between the... line bearing 166°50′ true from latitude 40°50′17.337 N, longitude 73°43′03.877 W, which point is on the...

76 FR 20532 - Safety Zone; Boom Days, Niagara River, Niagara Falls, NY

Science.gov (United States)

2011-04-13

...-AA00 Safety Zone; Boom Days, Niagara River, Niagara Falls, NY AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing a temporary safety zone on the Niagara River... Marina and a portion of the Niagara River, Niagara Falls, NY during the Boom Days Fireworks on April 16...

2008 FEMA Lidar: South Oneida County (NY)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — For Oneida County, NY, there were two types of elevation datasets. The first type is LiDAR and the second one is Auto-correlation DEM. Auto-correlation DEM data was...

Strategy for monitoring T cell responses to NY-ESO-1 in patients with any HLA class I allele

Science.gov (United States)

Gnjatic, Sacha; Nagata, Yasuhiro; Jäger, Elke; Stockert, Elisabeth; Shankara, Srinivas; Roberts, Bruce L.; Mazzara, Gail P.; Lee, Sang Yull; Dunbar, P. Rod; Dupont, Bo; Cerundolo, Vincenzo; Ritter, Gerd; Chen, Yao-Tseng; Knuth, Alexander; Old, Lloyd J.

2000-01-01

NY-ESO-1 elicits frequent antibody responses in cancer patients, accompanied by strong CD8+ T cell responses against HLA-A2-restricted epitopes. To broaden the range of cancer patients who can be assessed for immunity to NY-ESO-1, a general method was devised to detect T cell reactivity independent of prior characterization of epitopes. A recombinant adenoviral vector encoding the full cDNA sequence of NY-ESO-1 was used to transduce CD8-depleted peripheral blood lymphocytes as antigen-presenting cells. These modified antigen-presenting cells were then used to restimulate memory effector cells against NY-ESO-1 from the peripheral blood of cancer patients. Specific CD8+ T cells thus sensitized were assayed on autologous B cell targets infected with a recombinant vaccinia virus encoding NY-ESO-1. Strong polyclonal responses were observed against NY-ESO-1 in antibody-positive patients, regardless of their HLA profile. Because the vectors do not cross-react immunologically, only responses to NY-ESO-1 were detected. The approach described here allows monitoring of CD8+ T cell responses to NY-ESO-1 in the context of various HLA alleles and has led to the definition of NY-ESO-1 peptides presented by HLA-Cw3 and HLA-Cw6 molecules. PMID:11005863

WE-C-TOUR-T-00: Exhibit Hall Guided Tours-Microdosimeters for Therapy (Wednesday) WE-C-TOUR-T-01

International Nuclear Information System (INIS)

2016-01-01

Tour Leader: Indra Das, NYU Langone Medical Center, New York, NY Tour Guides: Hsui Ai, Indiana University School of Medicine, Indianapolis, IN Paulina Galvis, NYU Langone Medical Center, New York, NY Olga Volotoskova, NYU Langone Medical Center, New York, NY Participating Vendors: IBA PTW – New York RTI Electronics, Inc. Standard Imaging, Inc. Sun Nuclear Corporation Small fields are increasing used in specialized radiation treatments such as Gammaknife, Cyberknife, Tomotherapy, IMRT, VMAT, SRS and SBRT. Due to small field size electron transport creates lateral electronic disequilibrium and thus dosimetry could be very difficult. Microdetectors are used for small field dosimetry which will be discussed in preface of this tour as below: Understanding small field e.g. meaning and definition of small field IAEA definition and approach Characteristics of microdetectors in terms of perturbation, recombination, correction Suitability of microdetectors in small field dosimetry

WE-C-TOUR-T-01: Microdosimeters for Therapy

International Nuclear Information System (INIS)

Das, I.

2016-01-01

Tour Leader: Indra Das, NYU Langone Medical Center, New York, NY Tour Guides: Hsui Ai, Indiana University School of Medicine, Indianapolis, IN Paulina Galvis, NYU Langone Medical Center, New York, NY Olga Volotoskova, NYU Langone Medical Center, New York, NY Participating Vendors: IBA PTW – New York RTI Electronics, Inc. Standard Imaging, Inc. Sun Nuclear Corporation Small fields are increasing used in specialized radiation treatments such as Gammaknife, Cyberknife, Tomotherapy, IMRT, VMAT, SRS and SBRT. Due to small field size electron transport creates lateral electronic disequilibrium and thus dosimetry could be very difficult. Microdetectors are used for small field dosimetry which will be discussed in preface of this tour as below: Understanding small field e.g. meaning and definition of small field IAEA definition and approach Characteristics of microdetectors in terms of perturbation, recombination, correction Suitability of microdetectors in small field dosimetry

27 CFR 26.11 - Meaning of terms.

Science.gov (United States)

2010-04-01

... headquarters port of the district (except the district of New York, N.Y.); the area directors of customs in the district of New York, N.Y.; and the port director at a port not designated as a headquarters port... estate, a partnership, an association, a company, or a corporation. Proof gallon. A gallon of liquid at...

78 FR 35596 - Special Local Regulation; Long Beach Regatta, Powerboat Race, Atlantic Ocean, Long Beach, NY

Science.gov (United States)

2013-06-13

... 1625-AA08 Special Local Regulation; Long Beach Regatta, Powerboat Race, Atlantic Ocean, Long Beach, NY... temporary special local regulation on the navigable waters of the Atlantic Ocean off Long Beach, NY during... powerboat racing regatta. The event will be held on the Atlantic Ocean off Long Beach, NY and will feature...

33 CFR 207.50 - Hudson River Lock at Troy, N.Y.; navigation.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Hudson River Lock at Troy, N.Y..., DEPARTMENT OF DEFENSE NAVIGATION REGULATIONS § 207.50 Hudson River Lock at Troy, N.Y.; navigation. (a...) [Reserved] (n) Trespass on U.S. property. Trespass on U.S. property, or willful injury to the banks, masonry...

Effect of vitamin C supplementation on stroke recovery: A case-control study

Directory of Open Access Journals (Sweden)

Meheroz H Rabadi

2007-04-01

Full Text Available Meheroz H Rabadi1, Bruce S Kristal2,31Burke Rehabilitation Hospital, an affiliate of Weill Medical College of Cornell Medical College, White Plains, NY, USA; 2Burke Medical Research Institute, an affiliate of Weill Medical College of Cornell Medical College, White Plains, NY, USA; 3Department of Neuroscience, Cornell University Medical College, White Plains, NY, USABackground and purpose: Epidemiological studies have associated increased dietary intake of antioxidants (vitamin C, E, and β-carotene in preventing and decreasing the extent of ischemic brain injury. The effect of vitamin C supplementation on functional recovery after stroke has not been studied. Method: In this retrospective, case-control study of 23 patients with ischemic stroke taking vitamin C were identified and matched for age, sex, onset to admission, and admission total functional independence measure (TFIM with 23 patients with ischemic stroke not taking Vitamin C supplementation. Vitamin C 1000 mg daily was prescribed on admission to our unit mainly to patients who were undernourished (defined as significant weight loss and/or 90% or less ideal body weight for age and sex and those with pressure sores. The outcome measures were: change in the TFIM, FIM-Cognition (FIM-Cog, and FIM-Motor sub-scores, discharge disposition, and length of stay (LOS.Results: The change in TFIM (20 ± 13 standard deviation [SD] vs. 26 ± 6, p = 0.20, FIM-Cog (3 ± 3 SD vs. 4 ± 5, p = 0.41, FIM-Motor (15 ± 11 SD vs. 20 ± 13, p = 0.21 sub-scores were less in the vitamin C treated group, but these differences did not reach statistical significance. Similarly, no significant differences were found in LOS (21 ± 9 SD vs. 23 ± 9, p = 0.59, and discharge disposition (home/institution (9/10 vs. 13/9, p = 0.60 between the vitamin C and the control groups.Conclusion: This study suggests vitamin C supplementation did not enhance functional recovery in undernourished ischemic stroke patients

76 FR 51885 - Safety Zone; Thunder on Niagara, Niagara River, North Tonawanda, NY

Science.gov (United States)

2011-08-19

... River, North Tonawanda, NY. This temporary safety zone is intended to restrict vessels from a portion of the Niagara River during the Thunder on Niagara powerboat races. This temporary safety zone is...-AA00 Safety Zone; Thunder on Niagara, Niagara River, North Tonawanda, NY AGENCY: Coast Guard, DHS...

Spontaneous CD8 T cell responses against the melanocyte differentiation antigen RAB38/NY-MEL-1 in melanoma patients.

Science.gov (United States)

Walton, Senta M; Gerlinger, Marco; de la Rosa, Olga; Nuber, Natko; Knights, Ashley; Gati, Asma; Laumer, Monika; Strauss, Laura; Exner, Carolin; Schäfer, Niklaus; Urosevic, Mirjana; Dummer, Reinhard; Tiercy, Jean-Marie; Mackensen, Andreas; Jaeger, Elke; Lévy, Frédéric; Knuth, Alexander; Jäger, Dirk; Zippelius, Alfred

2006-12-01

The melanocyte differentiation Ag RAB38/NY-MEL-1 was identified by serological expression cloning (SEREX) and is expressed in the vast majority of melanoma lesions. The immunogenicity of RAB38/NY-MEL-1 has been corroborated previously by the frequent occurrence of specific Ab responses in melanoma patients. To elucidate potential CD8 T cell responses, we applied in vitro sensitization with overlapping peptides spanning the RAB38/NY-MEL-1 protein sequence and the reverse immunology approach. The identified peptide RAB38/NY-MEL-1(50-58) exhibited a marked response in ELISPOT assays after in vitro sensitization of CD8 T cells from HLA-A *0201(+) melanoma patients. In vitro digestion assays using purified proteasomes provided evidence of natural processing of RAB38/NY-MEL-1(50-58) peptide. Accordingly, monoclonal RAB38/NY-MEL-1(50-58)-specific T cell populations were capable of specifically recognizing HLA-A2(+) melanoma cell lines expressing RAB38/NY-MEL-1. Applying fluorescent HLA-A2/RAB38/NY-MEL-1(50-58) multimeric constructs, we were able to document a spontaneously developed memory/effector CD8 T cell response against this peptide in a melanoma patient. To elucidate the Ag-processing pathway, we demonstrate that RAB38/NY-MEL-1(50-58) is produced efficiently by the standard proteasome and the immunoproteasome. In addition to the identification of a RAB38/NY-MEL-1-derived immunogenic CD8 T cell epitope, this study is instrumental for both the onset and monitoring of future RAB38/NY-MEL-1-based vaccination trials.

33 CFR 207.600 - Rochester (Charlotte) Harbor, N.Y.; use, administration, and navigation.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Rochester (Charlotte) Harbor, N.Y.; use, administration, and navigation. 207.600 Section 207.600 Navigation and Navigable Waters CORPS OF... (Charlotte) Harbor, N.Y.; use, administration, and navigation. (a)-(b) [Reserved] (c) No vessel shall moor or...

77 FR 39406 - Safety Zone; Tom Graves Memorial Fireworks, Port Bay, Wolcott, NY

Science.gov (United States)

2012-07-03

...-AA00 Safety Zone; Tom Graves Memorial Fireworks, Port Bay, Wolcott, NY AGENCY: Coast Guard, DHS. ACTION..., NY. This safety zone is intended to restrict vessels from a portion of Port Bay during the Tom Graves... necessary to ensure the safety of spectators and vessels during the Tom Graves Memorial Fireworks. This zone...

In silico SNP analysis of the breast cancer antigen NY-BR-1.

Science.gov (United States)

Kosaloglu, Zeynep; Bitzer, Julia; Halama, Niels; Huang, Zhiqin; Zapatka, Marc; Schneeweiss, Andreas; Jäger, Dirk; Zörnig, Inka

2016-11-18

Breast cancer is one of the most common malignancies with increasing incidences every year and a leading cause of death among women. Although early stage breast cancer can be effectively treated, there are limited numbers of treatment options available for patients with advanced and metastatic disease. The novel breast cancer associated antigen NY-BR-1 was identified by SEREX analysis and is expressed in the majority (>70%) of breast tumors as well as metastases, in normal breast tissue, in testis and occasionally in prostate tissue. The biological function and regulation of NY-BR-1 is up to date unknown. We performed an in silico analysis on the genetic variations of the NY-BR-1 gene using data available in public SNP databases and the tools SIFT, Polyphen and Provean to find possible functional SNPs. Additionally, we considered the allele frequency of the found damaging SNPs and also analyzed data from an in-house sequencing project of 55 breast cancer samples for recurring SNPs, recorded in dbSNP. Over 2800 SNPs are recorded in the dbSNP and NHLBI ESP databases for the NY-BR-1 gene. Of these, 65 (2.07%) are synonymous SNPs, 191 (6.09%) are non-synoymous SNPs, and 2430 (77.48%) are noncoding intronic SNPs. As a result, 69 non-synoymous SNPs were predicted to be damaging by at least two, and 16 SNPs were predicted as damaging by all three of the used tools. The SNPs rs200639888, rs367841401 and rs377750885 were categorized as highly damaging by all three tools. Eight damaging SNPs are located in the ankyrin repeat domain (ANK), a domain known for its frequent involvement in protein-protein interactions. No distinctive features could be observed in the allele frequency of the analyzed SNPs. Considering these results we expect to gain more insights into the variations of the NY-BR-1 gene and their possible impact on giving rise to splice variants and therefore influence the function of NY-BR-1 in healthy tissue as well as in breast cancer.

Flood-inundation maps for Lake Champlain in Vermont and in northern Clinton County, New York

Science.gov (United States)

Flynn, Robert H.; Hayes, Laura

2016-06-30

Digital flood-inundation maps for an approximately100-mile length of Lake Champlain in Addison, Chittenden, Franklin, and Grand Isle Counties in Vermont and northern Clinton County in New York were created by the U.S. Geological Survey (USGS) in cooperation with the International Joint Commission (IJC). The flood-inundationmaps, which can be accessed through the International Joint Commission (IJC) Web site at http://www.ijc.org/en_/, depict estimates of the areal extent flooding correspondingto selected water levels (stages) at the USGS lake gage on the Richelieu River (Lake Champlain) at Rouses Point, N.Y. (station number 04295000). In this study, wind and seiche effects (standing oscillating wave with a long wavelength) were not taken into account and the flood-inundation mapsreflect 11 stages (elevations) for Lake Champlain that are static for the study length of the lake. Near-real-time stages at this lake gage, and others on Lake Champlain, may be obtained on the Internet from the USGS National Water Information System at http://waterdata.usgs.gov/ or the National Weather Service Advanced Hydrologic Prediction Service at http:/water.weather.gov/ahps/, which also forecasts flood hydrographs at the Richelieu River (Lake Champlain) at Rouses Point.Static flood boundary extents were determined for LakeChamplain in Addison, Chittenden, Franklin, and Grand Isle Counties in Vermont and northern Clinton County in New York using recently acquired (2013–2014) lidar (light detection and ranging) and may be referenced to any of the five USGS lake gages on Lake Champlain. Of these five lakgages, USGS lake gage 04295000, Richelieu River (Lake Champlain) at Rouses Point, N.Y., is the only USGS lake gage that is also a National Weather Service prediction location. Flood boundary extents for the Lake Champlain static flood-inundation map corresponding to the May 201 flood(103.2 feet [ft], National Geodetic Vertical Datum [NGVD] 29) were evaluated by comparing these boundary

Coenzyme Q10 effects in neurodegenerative disease

Directory of Open Access Journals (Sweden)

Meredith Spindler

2009-11-01

Full Text Available Meredith Spindler1, M Flint Beal1,2, Claire Henchcliffe1,21Department of Neurology, 2Department of Neuroscience, Weill Medical College of Cornell University, New York, NY, USAAbstract: Coenzyme Q10 (CoQ10 is an essential cofactor in the mitochondrial respiratory chain, and as a dietary supplement it has recently gained attention for its potential role in the treatment of neurodegenerative disease. Evidence for mitochondrial dysfunction in neurodegenerative disorders derives from animal models, studies of mitochondria from patients, identification of genetic defects in patients with neurodegenerative disease, and measurements of markers of oxidative stress. Studies of in vitro models of neuronal toxicity and animal models of neurodegenerative disorders have demonstrated potential neuroprotective effects of CoQ10. With this data in mind, several clinical trials of CoQ10 have been performed in Parkinson’s disease and atypical Parkinson’s syndromes, Huntington’s disease, Alzheimer disease, Friedreich’s ataxia, and amyotrophic lateral sclerosis, with equivocal findings. CoQ10 is widely available in multiple formulations and is very well tolerated with minimal adverse effects, making it an attractive potential therapy. Phase III trials of high-dose CoQ10 in large sample sizes are needed to further ascertain the effects of CoQ10 in neurodegenerative diseases.Keywords: coenzyme Q10, neurodegenerative disease, Parkinson’s disease, Huntington’s disease, mitochondrial dysfunction

Anesthesia for the patient undergoing total knee replacement: current status and future prospects

Directory of Open Access Journals (Sweden)

Turnbull ZA

2017-03-01

Full Text Available Zachary A Turnbull, Dahniel Sastow, Gregory P Giambrone, Tiffany Tedore Department of Anesthesiology, Weill Cornell Medical College, New York, NY, USA Abstract: Total knee arthroplasty (TKA has become one of the most common orthopedic surgical procedures performed nationally. As the population and surgical techniques for TKAs have evolved over time, so have the anesthesia and analgesia used for these procedures. General anesthesia has been the dominant form of anesthesia utilized for TKA in the past, but regional anesthetic techniques are on the rise. Multiple studies have shown the potential for regional anesthesia to improve patient outcomes, such as a decrease in intraoperative blood loss, length of stay, and patient mortality. Anesthesiologists are also moving toward multimodal analgesia, which includes peripheral nerve blockade, periarticular injection, and preemptive analgesia. The goal of multimodal analgesia is to improve perioperative pain control while minimizing systemic narcotic consumption. With improved postoperative pain management and rapid patient rehabilitation, new clinical pathways have been engineered to fast track patient recovery after orthopedic procedures. The aim of these clinical pathways was to improve quality of care, minimize unnecessary variations in care, and reduce cost by using streamlined procedures and protocols. The future of TKA care will be formalized clinical pathways and tracks to better optimize perioperative algorithms with regard to pain control and perioperative rehabilitation. Keywords: TKA, regional anesthesia, analgesia

Vesicular stomatitis virus modified with single chain IL-23 exhibits oncolytic activity against tumor cells in vitro and in vivo

OpenAIRE

Reiss, Carol Shoshkes

2010-01-01

James M Miller1, Sarah McNulty Bidula1,5, Troels Mygind Jensen1,6, Carol Shoshkes Reiss1,2,3,41Department of Biology, New York University, New York, NY, USA; 2Center for Neural Science, NYU; 3NYU Cancer Institute; 4Departments of Microbiology, NYU School of Medicine and Mt Sinai School of Medicine, New York, NY, USA; 5Present address Graduate Program, University of Pittsburgh School of Medicine, Pittsburgh, PA,USA 6Present address: Univercity of Copenhagen, Copenhagen, DenmarkAbstract: Viruse...

33 CFR 207.590 - Black Rock Canal and Lock at Buffalo, N.Y.; use, administration, and navigation.

Science.gov (United States)

2010-07-01

... Buffalo, N.Y.; use, administration, and navigation. 207.590 Section 207.590 Navigation and Navigable... Black Rock Canal and Lock at Buffalo, N.Y.; use, administration, and navigation. (a) The term “canal... immediately to the Black Rock Lock, foot of Bridge Street, Buffalo, N.Y., telephone 876-5454. (k) Ferry Street...

The New York Head-A precise standardized volume conductor model for EEG source localization and tES targeting.

Science.gov (United States)

Huang, Yu; Parra, Lucas C; Haufe, Stefan

2016-10-15

In source localization of electroencephalograpic (EEG) signals, as well as in targeted transcranial electric current stimulation (tES), a volume conductor model is required to describe the flow of electric currents in the head. Boundary element models (BEM) can be readily computed to represent major tissue compartments, but cannot encode detailed anatomical information within compartments. Finite element models (FEM) can capture more tissue types and intricate anatomical structures, but with the higher precision also comes the need for semi-automated segmentation, and a higher computational cost. In either case, adjusting to the individual human anatomy requires costly magnetic resonance imaging (MRI), and thus head modeling is often based on the anatomy of an 'arbitrary' individual (e.g. Colin27). Additionally, existing reference models for the human head often do not include the cerebro-spinal fluid (CSF), and their field of view excludes portions of the head and neck-two factors that demonstrably affect current-flow patterns. Here we present a highly detailed FEM, which we call ICBM-NY, or "New York Head". It is based on the ICBM152 anatomical template (a non-linear average of the MRI of 152 adult human brains) defined in MNI coordinates, for which we extended the field of view to the neck and performed a detailed segmentation of six tissue types (scalp, skull, CSF, gray matter, white matter, air cavities) at 0.5mm(3) resolution. The model was solved for 231 electrode locations. To evaluate its performance, additional FEMs and BEMs were constructed for four individual subjects. Each of the four individual FEMs (regarded as the 'ground truth') is compared to its BEM counterpart, the ICBM-NY, a BEM of the ICBM anatomy, an 'individualized' BEM of the ICBM anatomy warped to the individual head surface, and FEMs of the other individuals. Performance is measured in terms of EEG source localization and tES targeting errors. Results show that the ICBM-NY outperforms

Ejendomsordbogen fransk/dansk: ny integreret e-ordbog

DEFF Research Database (Denmark)

Leroyer, Patrick; Hansen, Liselotte Kruse

2012-01-01

fusionere med en praktisk guide. Til dette formål har vi udviklet konceptet til en ny type hybridordbog, der kan tilfredsstille de intenderede brugeres informationsbehov i kommunikative, kognitive og praktiske situationer. Udviklingen er sket i samarbejde med den førende udbyder af online ordbøger i Danmark...

The Storm Surge and Sub-Grid Inundation Modeling in New York City during Hurricane Sandy

Directory of Open Access Journals (Sweden)

Harry V. Wang

2014-03-01

Full Text Available Hurricane Sandy inflicted heavy damage in New York City and the New Jersey coast as the second costliest storm in history. A large-scale, unstructured grid storm tide model, Semi-implicit Eulerian Lagrangian Finite Element (SELFE, was used to hindcast water level variation during Hurricane Sandy in the mid-Atlantic portion of the U.S. East Coast. The model was forced by eight tidal constituents at the model’s open boundary, 1500 km away from the coast, and the wind and pressure fields from atmospheric model Regional Atmospheric Modeling System (RAMS provided by Weatherflow Inc. The comparisons of the modeled storm tide with the NOAA gauge stations from Montauk, NY, Long Island Sound, encompassing New York Harbor, Atlantic City, NJ, to Duck, NC, were in good agreement, with an overall root mean square error and relative error in the order of 15–20 cm and 5%–7%, respectively. Furthermore, using large-scale model outputs as the boundary conditions, a separate sub-grid model that incorporates LIDAR data for the major portion of the New York City was also set up to investigate the detailed inundation process. The model results compared favorably with USGS’ Hurricane Sandy Mapper database in terms of its timing, local inundation area, and the depth of the flooding water. The street-level inundation with water bypassing the city building was created and the maximum extent of horizontal inundation was calculated, which was within 30 m of the data-derived estimate by USGS.

Incorporating the principles of the patient- centered medical home into a student-run free clinic

Directory of Open Access Journals (Sweden)

Riddle MC

2014-09-01

Full Text Available Megan C Riddle,1,* Jiahui Lin,3,* Jonathan B Steinman,2 Joshua D Salvi,2 Margaret M Reynolds,3 Anne S Kastor,3,† Christina Harris,4 Carla Boutin-Foster3 1Department of Psychiatry and Behavioral Sciences, University of Washington, 2Weill Cornell/Rockefeller/Sloan-Kettering Tri-Institutional MD–PhD Program, 3Department of Internal Medicine, Weill Cornell Medical College, New York, NY, 4Department of Medicine, Division of General Internal Medicine, VA Greater Los Angeles Healthcare System, David Geffen School of Medicine at UCLA, LA, USA *These authors contributed equally to this work †Anne S Kastor passed away on July 5, 2013. Abstract: As the health care delivery landscape changes, medical schools must develop creative strategies for preparing future physicians to provide quality care in this new environment. Despite the growing prominence of the patient-centered medical home (PCMH as an effective model for health care delivery, few medical schools have integrated formal education on the PCMH into their curricula. Incorporating the PCMH model into medical school curricula is important to ensure that students have a comprehensive understanding of the different models of health care delivery and can operate effectively as physicians. The authors provide a detailed description of the process by which the Weill Cornell Community Clinic (WCCC, a student-run free clinic, has integrated PCMH principles into a service-learning initiative. The authors assessed patient demographics, diagnoses, and satisfaction along with student satisfaction. During the year after a PCMH model was adopted, 112 students and 19 licensed physicians volunteered their time. A review of the 174 patients seen from July 2011 to June 2012 found that the most common medical reasons for visits included management of hypertension, hyperlipidemia, diabetes, gastrointestinal conditions, arthritis, anxiety, and depression. During the year after the adoption of the PCMH model, 87

SOURCE APPORTIONMENT OF POLYCYCLIC AROMATIC HYDROCARBONS (PAHs) INTO CENTRAL PARK LAKE, NEW YORK CITY, OVER A CENTURY OF DEPOSITION

Science.gov (United States)

Yan, Beizhan; Bopp, Richard F.; Abrajano, Teofilo A.; Chaky, Damon; Chillrud, Steven N.

2014-01-01

Relative contributions of polycyclic aromatic hydrocarbons (PAHs) from combustion sources of wood, petroleum, and coal were computed in sediments from Central Park Lake in New York City (NY, USA) by chemical mass balance based on several reliable source indicators. These indicators are the ratio of retene to the sum of retene and chrysene, the ratio of 1,7-dimethylphenanthrene (DMP) to 1,7-DMP and 2,6-DMP, and the ratio of fluroanthene to fluroanthene and pyrene. The authors found that petroleum combustion–derived PAH fluxes generally followed the historical consumption data of New York State. Coal combustion-derived PAH flux peaked approximately in the late 1910s, remained at a relatively high level over the next 3 decades, then rapidly declined from the 1950s to the 1960s; according to historical New York State coal consumption data, however, there was a 2-peak trend, with peaks around the early 1920s and the mid-1940s. The 1940s peak was not observed in Central Park Lake, most likely because of the well-documented shift from coal to oil as the major residential heating fuel in New York City during the late 1930s. It was widely believed that the decreased PAH concentrations and fluxes in global sediments during the last century resulted from a major energy shift from coal to petroleum. The data, however, show that this shift occurred from 1945 through the 1960s and did not result in an obvious decline. The sharpest decrease, which occurred in the 1970s was not predominantly related to coal usage but rather was the result of multiple factors, including a decline in petroleum usage largely, the introduction of low sulfur–content fuel in New York City, and the introduction of emission-control technologies. PMID:24375577

Enhancing Unit Cohesion Via Social Media

Science.gov (United States)

2016-06-10

Leavenworth, March 22, 2016). 8 Jeremy Harris Lipschultz, Social Media Communication : Concepts, Practices, Data, Law and Ethics (New York, NY...Gazette 97, no. 2 (February 2013): 8-14. Lipschultz, Jeremy Harris. Social Media Communication : Concepts, Practices, Data, Law and Ethics . New York, NY... communicate , but usually limit their scope of online participation to simply obtaining a social media presence. Although having a presence online is

Kapitalismens dna i ny oversættelse

DEFF Research Database (Denmark)

Schanz, Hans-Jørgen

2013-01-01

Adam Smiths klassiske storværk om kapitalismen ’Nationernes velstand’ havde stor indflydelse på socialfilosofien, på Hegel, på Marx og liberaløkonomerne. Ny oversættelse yder omsider værket fuld respekt på dansk. Anmeldelse af: Adam Smith: Nationernes velstand. 441+ 519 sider. 699,95 kr...

Identification of NY-BR-1-specific CD4(+) T cell epitopes using HLA-transgenic mice.

Science.gov (United States)

Gardyan, Adriane; Osen, Wolfram; Zörnig, Inka; Podola, Lilli; Agarwal, Maria; Aulmann, Sebastian; Ruggiero, Eliana; Schmidt, Manfred; Halama, Niels; Leuchs, Barbara; von Kalle, Christof; Beckhove, Philipp; Schneeweiss, Andreas; Jäger, Dirk; Eichmüller, Stefan B

2015-06-01

Breast cancer represents the second most common cancer type worldwide and has remained the leading cause of cancer-related deaths among women. The differentiation antigen NY-BR-1 appears overexpressed in invasive mammary carcinomas compared to healthy breast tissue, thus representing a promising target antigen for T cell based tumor immunotherapy approaches. Since efficient immune attack of tumors depends on the activity of tumor antigen-specific CD4(+) effector T cells, NY-BR-1 was screened for the presence of HLA-restricted CD4(+) T cell epitopes that could be included in immunological treatment approaches. Upon NY-BR-1-specific DNA immunization of HLA-transgenic mice and functional ex vivo analysis, a panel of NY-BR-1-derived library peptides was determined that specifically stimulated IFNγ secretion among splenocytes of immunized mice. Following in silico analyses, four candidate epitopes were determined which were successfully used for peptide immunization to establish NY-BR-1-specific, HLA-DRB1*0301- or HLA-DRB1*0401-restricted CD4(+) T cell lines from splenocytes of peptide immunized HLA-transgenic mice. Notably, all four CD4(+) T cell lines recognized human HLA-DR-matched dendritic cells (DC) pulsed with lysates of NY-BR-1 expressing human tumor cells, demonstrating natural processing of these epitopes also within the human system. Finally, CD4(+) T cells specific for all four CD4(+) T cell epitopes were detectable among PBMC of breast cancer patients, showing that CD4(+) T cell responses against the new epitopes are not deleted nor inactivated by self-tolerance mechanisms. Our results present the first NY-BR-1-specific HLA-DRB1*0301- and HLA-DRB1*0401-restricted T cell epitopes that could be exploited for therapeutic intervention against breast cancer. © 2014 UICC.

A novel murine T-cell receptor targeting NY-ESO-1.

Science.gov (United States)

Rosati, Shannon F; Parkhurst, Maria R; Hong, Young; Zheng, Zhili; Feldman, Steven A; Rao, Mahadev; Abate-Daga, Daniel; Beard, Rachel E; Xu, Hui; Black, Mary A; Robbins, Paul F; Schrump, David A; Rosenberg, Steven A; Morgan, Richard A

2014-04-01

Cancer testis antigens, such as NY-ESO-1, are expressed in a variety of prevalent tumors and represent potential targets for T-cell receptor (TCR) gene therapy. DNA encoding a murine anti-NY-ESO-1 TCR gene (mTCR) was isolated from immunized HLA-A*0201 transgenic mice and inserted into a γ-retroviral vector. Two mTCR vectors were produced and used to transduce human PBL. Transduced cells were cocultured with tumor target cell lines and T2 cells pulsed with the NY-ESO-1 peptide, and assayed for cytokine release and cell lysis activity. The most active TCR construct was selected for production of a master cell bank for clinical use. mTCR-transduced PBL maintained TCR expression in short-term and long-term culture, ranging from 50% to 90% efficiency 7-11 days after stimulation and 46%-82% 10-20 days after restimulation. High levels of interferon-γ secretion were observed (1000-12000 pg/mL), in tumor coculture assays and recognition of peptide-pulsed cells was observed at 0.1 ng/mL, suggesting that the new mTCR had high avidity for antigen recognition. mTCR-transduced T cells also specifically lysed human tumor targets. In all assays, the mTCR was equivalent or better than the comparable human TCR. As the functional activity of TCR-transduced cells may be affected by the formation of mixed dimers, mTCRs, which are less likely to form mixed dimers with endogenous hTCRs, may be more effective in vivo. This new mTCR targeted to NY-ESO-1 represents a novel potential therapeutic option for adoptive cell-transfer therapy for a variety of malignancies.

Hydrogeologic correlations for selected wells on Long Island, New York; a data base with retrieval program

Science.gov (United States)

Buxton, H.T.; Shernoff, P.K.; Smolensky, D.A.

1989-01-01

Accurate delineation of the internal hydrogeologic structure of Long Island, NY is integral to the understanding and management of the groundwater system. This report presents a computerized data base of hydrogeologic correlations for 3,146 wells on Long Island and adjacent parts of New York City. The data base includes the well identification number, the latitude-longitude of the well location, the altitude of land surface at the well and of the bottom of the drilled hole, and the altitude of the top of the major hydrogeologic units penetrated by the well. A computer program is included that allows retrieval of selected types of data for all of, or any local area of, Long Island. These data retrievals are a valuable aid to the construction of hydrogeologic surface maps. (USGS)

Viral Diversity of House Mice in New York City.

Science.gov (United States)

Williams, Simon H; Che, Xiaoyu; Garcia, Joel A; Klena, John D; Lee, Bohyun; Muller, Dorothy; Ulrich, Werner; Corrigan, Robert M; Nichol, Stuart; Jain, Komal; Lipkin, W Ian

2018-04-17

The microbiome of wild Mus musculus (house mouse), a globally distributed invasive pest that resides in close contact with humans in urban centers, is largely unexplored. Here, we report analysis of the fecal virome of house mice in residential buildings in New York City, NY. Mice were collected at seven sites in Manhattan, Queens, Brooklyn, and the Bronx over a period of 1 year. Unbiased high-throughput sequencing of feces revealed 36 viruses from 18 families and 21 genera, including at least 6 novel viruses and 3 novel genera. A representative screen of 15 viruses by PCR confirmed the presence of 13 of these viruses in liver. We identified an uneven distribution of diversity, with several viruses being associated with specific locations. Higher mouse weight was associated with an increase in the number of viruses detected per mouse, after adjusting for site, sex, and length. We found neither genetic footprints to known human viral pathogens nor antibodies to lymphocytic choriomeningitis virus. IMPORTANCE Mice carry a wide range of infectious agents with zoonotic potential. Their proximity to humans in the built environment is therefore a concern for public health. Laboratory mice are also the most common experimental model for investigating the pathobiology of infectious diseases. In this survey of mice trapped in multiple locations within New York City over a period of 1 year, we found a diverse collection of viruses that includes some previously not associated with house mice and others that appear to be novel. Although we found no known human pathogens, our findings provide insights into viral ecology and may yield models that have utility for clinical microbiology. Copyright © 2018 Williams et al.

From single-site tantalum complexes to nanoparticles of TaxNy and TaOxNy supported on silica: elucidation of synthesis chemistry by dynamic nuclear polarization surface enhanced NMR spectroscopy and X-ray absorption spectroscopy

KAUST Repository

Mohandas, Janet Chakkamadathil; Abou-Hamad, Edy; Callens, Emmanuel; Samantaray, Manoja; Gajan, David; Gurinov, Andrei; Ma, Tao; Ould-Chikh, Samy; Hoffman, Adam S.; Gates, Bruce C.; Basset, Jean-Marie

2017-01-01

Air-stable catalysts consisting of tantalum nitride nanoparticles represented as a mixture of TaxNy and TaOxNy with diameters in the range of 0.5 to 3 nm supported on highly dehydroxylated silica were synthesized from TaMe5 (Me = methyl) and dimeric

33 CFR 165.166 - Safety Zone: Macy's July 4th Fireworks, East River, NY.

Science.gov (United States)

2010-07-01

... Fireworks, East River, NY. 165.166 Section 165.166 Navigation and Navigable Waters COAST GUARD, DEPARTMENT... § 165.166 Safety Zone: Macy's July 4th Fireworks, East River, NY. (a) Regulated area. The following area...) in length, carrying persons for the purpose of viewing the fireworks, may take position in an area...

Heterozygous NPR2 Mutations Cause Disproportionate Short Stature, Similar to Léri-Weill Dyschondrosteosis.

Science.gov (United States)

Hisado-Oliva, Alfonso; Garre-Vázquez, Ana I; Santaolalla-Caballero, Fabiola; Belinchón, Alberta; Barreda-Bonis, Ana C; Vasques, Gabriela A; Ramirez, Joaquin; Luzuriaga, Cristina; Carlone, Gianni; González-Casado, Isabel; Benito-Sanz, Sara; Jorge, Alexander A; Campos-Barros, Angel; Heath, Karen E

2015-08-01

SHOX mutations have been detected in approximately 70% of Léri-Weill dyschondrosteosis (LWD) and approximately 2.5% of idiopathic short stature (ISS) cases, suggesting the implication of other genes or loci. The recent identification of NPR2 mutations in ISS suggested that NPR2 mutations may also be involved in disproportionate short stature. The objective of the study was to investigate whether NPR2 mutations can account for a proportion of the cases referred for LWD and ISS in whom no SHOX mutation was detected. We undertook NPR2 mutation screening in 173 individuals referred for suspected LWD and 95 for ISS, with no known defect in SHOX or its enhancers. Intracellular localization and natriuretic peptide precursor C-dependent guanylate cyclase activity were determined for the identified NPR2 variants. Eight NPR2 variants were identified in nine individuals, seven referred for suspected LWD and two for ISS. Six were demonstrated to affect NPR-B cell trafficking and/or its ability to synthesize cyclic GMP (cGMP) under response to natriuretic peptide precursor C/brain natriuretic peptide stimulation. All pathogenic mutations were detected in the suspected LWD referral group (∼3%). Interestingly, one of these patients is currently being treated with recombinant human GH and in contrast to previous reports is showing a positive response to the treatment. NPR2 mutations account for approximately 3% of patients with disproportionate short stature and/or clinical or radiographic indicators of SHOX deficiency and in whom no SHOX defect has been identified. However, no patient has yet presented with Madelung deformity. Thus, NPR2 should be screened in the SHOX-negative LWD referrals.

Critical modeling parameters identified for 3D CFD modeling of rectangular final settling tanks for New York City wastewater treatment plants.

Science.gov (United States)

Ramalingam, K; Xanthos, S; Gong, M; Fillos, J; Beckmann, K; Deur, A; McCorquodale, J A

2012-01-01

New York City Environmental Protection is in the process of incorporating biological nitrogen removal (BNR) in its wastewater treatment plants (WWTPs) which entails operating the aeration tanks with higher levels of mixed liquor suspended solids (MLSS) than a conventional activated sludge process. The objective of this paper is to discuss two of the important parameters introduced in the 3D CFD model that has been developed by the City College of New York (CCNY) group: (a) the development of the 'discrete particle' measurement technique to carry out the fractionation of the solids in the final settling tank (FST) which has critical implications in the prediction of the effluent quality; and (b) the modification of the floc aggregation (K(A)) and floc break-up (K(B)) coefficients that are found in Parker's flocculation equation (Parker et al. 1970, 1971) used in the CFD model. The dependence of these parameters on the predictions of the CFD model will be illustrated with simulation results on one of the FSTs at the 26th Ward WWTP in Brooklyn, NY.

Cancer testis antigens and NY-BR-1 expression in primary breast cancer: prognostic and therapeutic implications.

Science.gov (United States)

Balafoutas, Dimitrios; zur Hausen, Axel; Mayer, Sebastian; Hirschfeld, Marc; Jaeger, Markus; Denschlag, Dominik; Gitsch, Gerald; Jungbluth, Achim; Stickeler, Elmar

2013-06-03

Cancer-testis antigens (CTA) comprise a family of proteins, which are physiologically expressed in adult human tissues solely in testicular germ cells and occasionally placenta. However, CTA expression has been reported in various malignancies. CTAs have been identified by their ability to elicit autologous cellular and or serological immune responses, and are considered potential targets for cancer immunotherapy. The breast differentiation antigen NY-BR-1, expressed specifically in normal and malignant breast tissue, has also immunogenic properties. Here we evaluated the expression patterns of CTAs and NY-BR-1 in breast cancer in correlation to clinico-pathological parameters in order to determine their possible impact as prognostic factors. The reactivity pattern of various mAbs (6C1, MA454, M3H67, 57B, E978, GAGE #26 and NY-BR-1 #5) were assessed by immunohistochemistry in a tissue micro array series of 210 randomly selected primary invasive breast cancers in order to study the diversity of different CTAs (e.g. MAGE-A, NY-ESO-1, GAGE) and NY-BR-1. These expression data were correlated to clinico-pathological parameters and outcome data including disease-free and overall survival. Expression of at least one CTA was detectable in the cytoplasm of tumor cells in 37.2% of the cases. NY-BR-1 expression was found in 46.6% of tumors, respectively. Overall, CTA expression seemed to be linked to adverse prognosis and M3H67 immunoreactivity specifically was significantly correlated to shorter overall and disease-free survival (p=0.000 and 0.024, respectively). Our findings suggest that M3H67 immunoreactivity could serve as potential prognostic marker in primary breast cancer patients. The exclusive expression of CTAs in tumor tissues as well as the frequent expression of NY-BR-1 could define new targets for specific breast cancer therapies.

Transition Workbook for Combat Veterans. Postdeployment User Guide

Science.gov (United States)

2009-01-01

for Cognitive Therapy and Research. (2008). For consumers. http://www.beckinstitute.org/FolderID/223/SessionID/a/PageVars/Library/ InfoManage...particularly in the late afternoon or evening, including alcohol, caffeine, chocolate , and tobacco. 11. If you find there is a specific task or problem that... therapy and the emotional disorders. New York, NY: Penguin Books; 1979. 22. Burns DD. Feeling good: The new mood therapy . New York, NY: Harper Collins

Breaking Bad: The Efficacy of Ethics Education in Air Force Officer PME

Science.gov (United States)

2015-02-12

of Teaching Ethics in the Military?” in Ethics Education in the Military, eds. Paul Robinson, Nigel De Lee, and Don Carrick (Burlington, VT: Ashgate...Decision Making: Social Dilemmas, Social Values, and Ethical Judgments, (New York, NY: Taylor and Francis Group, 2010), 288. 25. Ronald F. Duska and...Decision Making: Social Dilemmas, Social Values, and Ethical Judgments. (New York, NY: Taylor and Francis Group, 2010), 259. 41. Jones and Ryan, “The

33 CFR 162.20 - Flushing Bay near La Guardia Airport, Flushing, N.Y.; restricted area.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Flushing Bay near La Guardia Airport, Flushing, N.Y.; restricted area. 162.20 Section 162.20 Navigation and Navigable Waters COAST... NAVIGATION REGULATIONS § 162.20 Flushing Bay near La Guardia Airport, Flushing, N.Y.; restricted area. (a...

Spatial Analysis of Geothermal Resource Potential in New York and Pennsylvania: A Stratified Kriging Approach

Science.gov (United States)

Smith, J. D.; Whealton, C. A.; Stedinger, J. R.

2014-12-01

Resource assessments for low-grade geothermal applications employ available well temperature measurements to determine if the resource potential is sufficient for supporting district heating opportunities. This study used a compilation of bottomhole temperature (BHT) data from recent unconventional shale oil and gas wells, along with legacy oil, gas, and storage wells, in Pennsylvania (PA) and New York (NY). Our study's goal was to predict the geothermal resource potential and associated uncertainty for the NY-PA region using kriging interpolation. The dataset was scanned for outliers, and some observations were removed. Because these wells were drilled for reasons other than geothermal resource assessment, their spatial density varied widely. An exploratory spatial statistical analysis revealed differences in the spatial structure of the geothermal gradient data (the kriging semi-variogram and its nugget variance, shape, sill, and the degree of anisotropy). As a result, a stratified kriging procedure was adopted to better capture the statistical structure of the data, to generate an interpolated surface, and to quantify the uncertainty of the computed surface. The area was stratified reflecting different physiographic provinces in NY and PA that have geologic properties likely related to variations in the value of the geothermal gradient. The kriging prediction and the variance-of-prediction were determined for each province by the generation of a semi-variogram using only the wells that were located within that province. A leave-one-out cross validation (LOOCV) was conducted as a diagnostic tool. The results of stratified kriging were compared to kriging using the whole region to determine the impact of stratification. The two approaches provided similar predictions of the geothermal gradient. However, the variance-of-prediction was different. The stratified approach is recommended because it gave a more appropriate site-specific characterization of uncertainty

Interoperability of Demand Response Resources Demonstration in NY

Energy Technology Data Exchange (ETDEWEB)

Wellington, Andre

2014-03-31

The Interoperability of Demand Response Resources Demonstration in NY (Interoperability Project) was awarded to Con Edison in 2009. The objective of the project was to develop and demonstrate methodologies to enhance the ability of customer sited Demand Response resources to integrate more effectively with electric delivery companies and regional transmission organizations.

Evaluering af ny kokkeuddannelse for hørehandicappede

DEFF Research Database (Denmark)

Hansen, Niels-Henrik Møller

2010-01-01

Center for Ungdomsforskning har netop afsluttet en evaluering af en ny uddannelse indenfor madproduktion, rettet imod personer med et hørehandicap. Hensigten med uddannelsen er, at kunne tilbyde døve, døvblinde og hørehæmmede personer et uddannelsestilbud indenfor fremstilling af mad. Konkret han...

Bathymetric survey of the Cayuga Inlet flood-control channel and selected tributaries in Ithaca, New York, 2016

Science.gov (United States)

Wernly, John F.; Nystrom, Elizabeth A.; Coon, William F.

2017-09-08

From July 14 to July 20, 2016, the U.S. Geological Survey, in cooperation with the City of Ithaca, New York, and the New York State Department of State, surveyed the bathymetry of the Cayuga Inlet flood-control channel and the mouths of selected tributaries to Cayuga Inlet and Cayuga Lake in Ithaca, N.Y. The flood-control channel, built by the U.S. Army Corps of Engineers between 1965 and 1970, was designed to convey flood flows from the Cayuga Inlet watershed through the City of Ithaca and minimize possible flood damages. Since that time, the channel has infrequently been maintained by dredging, and sediment accumulation and resultant shoaling have greatly decreased the conveyance of the channel and its navigational capability.U.S. Geological Survey personnel collected bathymetric data by using an acoustic Doppler current profiler. The survey produced a dense dataset of water depths that were converted to bottom elevations. These elevations were then used to generate a geographic information system bathymetric surface. The bathymetric data and resultant bathymetric surface show the current condition of the channel and provide the information that governmental agencies charged with maintaining the Cayuga Inlet for flood-control and navigational purposes need to make informed decisions regarding future maintenance measures.

78 FR 24677 - Safety Zone; XA The Experimental Agency Fireworks, Pier 34, East River, NY

Science.gov (United States)

2013-04-26

... Final Rule This rule establishes a temporary safety zone on the navigable waters of the East River, in... Fireworks, Pier 34, East River, NY. (a) Regulated Area. The following area is a temporary safety zone: all... 1625-AA00 Safety Zone; XA The Experimental Agency Fireworks, Pier 34, East River, NY AGENCY: Coast...

33 CFR 110.84 - Black Rock Channel opposite foot of Porter Avenue, Buffalo, N.Y.

Science.gov (United States)

2010-07-01

... of Porter Avenue, Buffalo, N.Y. 110.84 Section 110.84 Navigation and Navigable Waters COAST GUARD... Channel opposite foot of Porter Avenue, Buffalo, N.Y. An area extending northwesterly between Black Rock... Triangulation Marker “N-5” on Bird Island Pier; thence southeasterly along the pier a distance of approximately...

Synoptic-scale atmospheric conditions associated with flash flooding in watersheds of the Catskill Mountains, New York, USA

Science.gov (United States)

Teale, N. G.; Quiring, S. M.

2015-12-01

Understanding flash flooding is important in unfiltered watersheds, such as portions of the New York City water supply system (NYCWSS), as water quality is degraded by turbidity associated with flooding. To further understand flash flooding in watersheds of the NYCWSS, synoptic-scale atmospheric conditions most frequently associated with flash flooding between 1987 and 2013 were examined. Flash floods were identified during this time period using USGS 15-minute discharge data at the Esopus Creek near Allaben, NY and Neversink River at Claryville, NY gauges. Overall, 25 flash floods were detected, occurring over 17 separate flash flood days. These flash flood days were compared to the days on which flash flood warnings encompassing the study area was issued by the National Weather Service. The success rate for which the flash flood warnings for Ulster County coincided with flash flood in the study watershed was 0.09, demonstrating the highly localized nature of flash flooding in the Catskill Mountain region. The synoptic-scale atmospheric patterns influencing the study area were characterized by a principal component analysis and k-means clustering of NCEP/NCAR 500 mb geopotential height reanalysis data. This procedure was executed in Spatial Synoptic Typer Tools 4.0. While 17 unique synoptic patterns were identified, only 3 types were strongly associated with flash flooding events. A strong southwesterly flow suggesting advection of moisture from the Atlantic Ocean and Gulf of Mexico is shown in composites of these 3 types. This multiscalar study thereby links flash flooding in the NYCWSS with synoptic-scale atmospheric circulation.Understanding flash flooding is important in unfiltered watersheds, such as portions of the New York City water supply system (NYCWSS), as water quality is degraded by turbidity associated with flooding. To further understand flash flooding in watersheds of the NYCWSS, synoptic-scale atmospheric conditions most frequently associated with

Persistent deNOx Ability of CaAl2O4:(Eu, Nd/TiO2-xNy Luminescent Photocatalyst

Directory of Open Access Journals (Sweden)

Li Huihui

2011-01-01

Full Text Available Abstract CaAl2O4:(Eu, Nd/TiO2-xNy composite luminescent photocatalyst was successfully synthesized by a simple planetary ball milling process. Improvement of photocatalytic deNOx ability of TiO2-xNy, together with the persistent photocatalytic activity for the decomposition of NO after turning off the light were realized, by coupling TiO2-xNy with long afterglow phosphor, CaAl2O4:(Eu, Nd. The novel persistent photocatalytic behavior was related to the overlap between the absorption wavelength of TiO2-xNy and the emission wavelength of the CaAl2O4:(Eu, Nd. It was found that CaAl2O4:(Eu, Nd/TiO2-xNy composites provided the luminescence to persist photocatalytic reaction for more than 3 h after turning off the light. Graphical Abstract CaAl2O4:(Eu, Nd/TiO2-xNy composite luminescent photocatalyst with persistent deNOx activity after turning off the light was successfully synthesized by a simple planetary ball milling process. The novel persistent photocatalytic behavior was related to the overlap between the absorption wavelength of TiO2-xNy and the emission wavelength of the CaAl2O4:(Eu, Nd. Additional file 1 Click here for file

Parkinson's Disease Videos

Medline Plus

Full Text Available ... Skills for Parkinson's Care Partners Expert Briefings: What's New in Genetics and Parkinson's? Expert Briefings: Understanding the ... Miami, FL 33131 NY: 1359 Broadway, Suite 1509, New York, NY 10018 contact@parkinson.org Press Room ...

Site differences in mild cognitive dysfunction (MCD) among patients with systemic lupus erythematosus (SLE).

Science.gov (United States)

Kozora, E; Erkan, D; West, S G; Filley, C M; Zhang, L; Ramon, G; Duggan, E; Lockshin, M D

2013-01-01

Mild cognitive dysfunction (MCD) is common in patients with systemic lupus erythematosus (MCD-SLE) but few studies have investigated potential site differences. SLE patients from Denver, CO, and New York, NY, were enrolled in two different cognition studies employing similar screening methods. Using the resulting neuropsychological scores, cognitive impairment was calculated using a cognitive impairment index (CII). The rate of MCD-SLE was 24% at the Denver, CO, site and 60% at the New York, NY, site. The mean CII was 2.6 ± 2.3 versus 4.4 ± 2.7, respectively (p = 0.005). The NY participants had a significantly longer disease duration (p = 0.13) and higher American College of Rheumatology SLE criteria scores (p > 0.001). NY participants had a higher frequency of impairment in semantic verbal fluency (p = 0.005), visuomotor speed (p = 0.013), and motor sequencing (p = 0.001). A correlation was found between cognitive impairment and SLE disease duration (p = 0.03). The rate of MCD-SLE was greater in SLE patients from New York, NY, compared to patients in the Denver, CO, area. The greater duration of disease and higher prevalence of medical complications in the NY group might contribute to this difference. Findings suggest that MCD-SLE may differ by site, but future studies that better evaluate site or selection bias are recommended.

Treatment with 5-Aza-2'-Deoxycytidine Induces Expression of NY-ESO-1 and Facilitates Cytotoxic T Lymphocyte-Mediated Tumor Cell Killing.

Directory of Open Access Journals (Sweden)

Agnes S Klar

Full Text Available NY-ESO-1 belongs to the cancer/testis antigen (CTA family and represents an attractive target for cancer immunotherapy. Its expression is induced in a variety of solid tumors via DNA demethylation of the promoter of CpG islands. However, NY-ESO-1 expression is usually very low or absent in some tumors such as breast cancer or multiple myeloma. Therefore, we established an optimized in vitro treatment protocol for up-regulation of NY-ESO-1 expression by tumor cells using the hypomethylating agent 5-aza-2'-deoxycytidine (DAC.We demonstrated de novo induction of NY-ESO-1 in MCF7 breast cancer cells and significantly increased expression in U266 multiple myeloma cells. This effect was time- and dose-dependent with the highest expression of NY-ESO-1 mRNA achieved by the incubation of 10 μM DAC for 72 hours. NY-ESO-1 activation was also confirmed at the protein level as shown by Western blot, flow cytometry, and immunofluorescence staining. The detection and quantification of single NY-ESO-1 peptides presented at the tumor cell surface in the context of HLA-A*0201 molecules revealed an increase of 100% and 50% for MCF7 and U266 cells, respectively. Moreover, the enhanced expression of NY-ESO-1 derived peptides at the cell surface was accompanied by an increased specific lysis of MCF7 and U266 cells by HLA-A*0201/NY-ESO-1(157-165 peptide specific chimeric antigen receptor (CAR CD8+ T cells. In addition, the killing activity of CAR T cells correlated with the secretion of higher IFN-gamma levels.These results indicate that NY-ESO-1 directed immunotherapy with specific CAR T cells might benefit from concomitant DAC treatment.

75 FR 3251 - JP Morgan Chase and Company; JP Morgan Investment Banking, Global Corporate Financial Operations...

Science.gov (United States)

2010-01-20

... Company; JP Morgan Investment Banking, Global Corporate Financial Operations, New York, NY; Notice of... Company, JP Morgan Investment Banking, Global Corporate Financial Operations, New York, New York. The... support operations to/from a foreign country. The subject firm did not import services like or directly...

Matter of 381 Search Warrants Directed to Facebook, 2017 N.Y. Lexis 767, 2; 2017 NY Slip op. 02586, 2 (N.Y. April 4, 2017

Directory of Open Access Journals (Sweden)

Trad. Leopoldo Villar

2017-08-01

Full Text Available The growing importance of electronic communications gives a special interest to its protection, which involves several fundamental rights and guarantees such as freedom, privacy and property. Due to the importance of the discussion and the different positions it reflects on an issue of such sensitivity and pertinence in the world today, we publish below the translation of the decision by the Supreme Court of the State of New York of April 4, 2017, on the 381 search warrants directed to Facebook user accounts, ordered by the same Court in 2013 in response to a request by the New York County District Attorney, supported in turn by an affidavit given by a prosecutor in a criminal investigation. Facebook filed a motion seeking annulment of the search warrants and disclosure of the Prosecutor’s affidavit but both motions were rejected by the Appeals Division, whereupon Facebook appealed to the New York Supreme Court, which dismissed the appeal. Although most agreed that the appeal was not appropriate, the views of the judges contain interpretations that make their reading very useful and particularly the opinión given by the dissenting judge offers enriching arguments for defending the rights of users of electronic services.

Den fjerde vej: Trumps sejr skaber ny samfundsorden

DEFF Research Database (Denmark)

Rasmussen, Martin Møller Boje; Andersen, Torben K.; Kragh, Claus

2016-01-01

Bag Donald Trumps uempatiske retorik gemmer sig omridset af et politisk projekt, man kan kalde den fjerde vej. USA’s kommende præsident blander højre- og venstreorienterede mærkesager til et nyt nationalsocialt politisk koncept. Spørgsmålet er, om Trumps fjerde vej er et seriøst bud på en ny...

New York Blue

Data.gov (United States)

Federal Laboratory Consortium — New York Blue is used cooperatively by the Laboratory and Stony Brook University as part of the New York Center for Computation Sciences. Ranked as the 28th fastest...

A Novel A(H7N2) Influenza Virus Isolated from a Veterinarian Caring for Cats in a New York City Animal Shelter Causes Mild Disease and Transmits Poorly in the Ferret Model.

Science.gov (United States)

Belser, Jessica A; Pulit-Penaloza, Joanna A; Sun, Xiangjie; Brock, Nicole; Pappas, Claudia; Creager, Hannah M; Zeng, Hui; Tumpey, Terrence M; Maines, Taronna R

2017-08-01

In December 2016, a low-pathogenic avian influenza (LPAI) A(H7N2) virus was identified to be the causative source of an outbreak in a cat shelter in New York City, which subsequently spread to multiple shelters in the states of New York and Pennsylvania. One person with occupational exposure to infected cats became infected with the virus, representing the first LPAI H7N2 virus infection in a human in North America since 2003. Considering the close contact that frequently occurs between companion animals and humans, it was critical to assess the relative risk of this novel virus to public health. The virus isolated from the human case, A/New York/108/2016 (NY/108), caused mild and transient illness in ferrets and mice but did not transmit to naive cohoused ferrets following traditional or aerosol-based inoculation methods. The environmental persistence of NY/108 virus was generally comparable to that of other LPAI H7N2 viruses. However, NY/108 virus replicated in human bronchial epithelial cells with an increased efficiency compared with that of previously isolated H7N2 viruses. Furthermore, the novel H7N2 virus was found to utilize a relatively lower pH for hemagglutinin activation, similar to human influenza viruses. Our data suggest that the LPAI H7N2 virus requires further adaptation before representing a substantial threat to public health. However, the reemergence of an LPAI H7N2 virus in the northeastern United States underscores the need for continuous surveillance of emerging zoonotic influenza viruses inclusive of mammalian species, such as domestic felines, that are not commonly considered intermediate hosts for avian influenza viruses. IMPORTANCE Avian influenza viruses are capable of crossing the species barrier to infect mammals, an event of public health concern due to the potential acquisition of a pandemic phenotype. In December 2016, an H7N2 virus caused an outbreak in cats in multiple animal shelters in New York State. This was the first

Spatio-temporal patterns of gun violence in Syracuse, New York 2009-2015.

Science.gov (United States)

Larsen, David A; Lane, Sandra; Jennings-Bey, Timothy; Haygood-El, Arnett; Brundage, Kim; Rubinstein, Robert A

2017-01-01

Gun violence in the United States of America is a large public health problem that disproportionately affects urban areas. The epidemiology of gun violence reflects various aspects of an infectious disease including spatial and temporal clustering. We examined the spatial and temporal trends of gun violence in Syracuse, New York, a city of 145,000. We used a spatial scan statistic to reveal spatio-temporal clusters of gunshots investigated and corroborated by Syracuse City Police Department for the years 2009-2015. We also examined predictors of areas with increased gun violence using a multi-level zero-inflated Poisson regression with data from the 2010 census. Two space-time clusters of gun violence were revealed in the city. Higher rates of segregation, poverty and the summer months were all associated with increased risk of gun violence. Previous gunshots in the area were associated with a 26.8% increase in the risk of gun violence. Gun violence in Syracuse, NY is both spatially and temporally stable, with some neighborhoods of the city greatly afflicted.

Massive transfusion protocols: current best practice

Directory of Open Access Journals (Sweden)

Hsu YM

2016-03-01

Full Text Available Yen-Michael S Hsu,1 Thorsten Haas,2 Melissa M Cushing1 1Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA; 2Department of Anesthesia, University Children's Hospital Zurich, Zurich, Switzerland Abstract: Massive transfusion protocols (MTPs are established to provide rapid blood replacement in a setting of severe hemorrhage. Early optimal blood transfusion is essential to sustain organ perfusion and oxygenation. There are many variables to consider when establishing an MTP, and studies have prospectively evaluated different scenarios and patient populations to establish the best practices to attain improved patient outcomes. The establishment and utilization of an optimal MTP is challenging given the ever-changing patient status during resuscitation efforts. Much of the MTP literature comes from the trauma population, due to the fact that massive hemorrhage is the leading cause of preventable trauma-related death. As we come to further understand the positive and negative clinical impacts of transfusion-related factors, massive transfusion practice can be further refined. This article will first discuss specific MTPs targeting different patient populations and current relevant international guidelines. Then, we will examine a wide selection of therapeutic products to support MTPs, including newly available products and the most suitable of the traditional products. Lastly, we will discuss the best design for an MTP, including ratio-based MTPs and MTPs based on the use of point-of-care coagulation diagnostic tools. Keywords: hemorrhage, MTP, antifibrinolytics, coagulopathy, trauma, ratio, logistics, guidelines, hemostatic

Review of levetiracetam, with a focus on the extended release formulation, as adjuvant therapy in controlling partial-onset seizures

Directory of Open Access Journals (Sweden)

Carol M Ulloa

2009-09-01

Full Text Available Carol M Ulloa, Allen Towfigh, Joseph SafdiehDepartment of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY, USAAbstract: Levetiracetam is a second-generation antiepileptic drug (AED with a unique chemical structure and mechanism of action. The extended release formulation of levetiracetam (Keppra XR™; UCB Pharma was recently approved by the Food and Drug Administration for adjunctive therapy in the treatment of partial-onset seizures in patients 16 years of age and older with epilepsy. This approval is based on a double-blind, randomized, placebo-controlled, multicenter, multinational trial. Levetiracetam XR allows for once-daily dosing, which may increase compliance and, given the relatively constant plasma concentrations, may minimize concentration-related adverse effects. Levetiracetam’s mode of action is not fully elucidated, but it has been found to target high-voltage, N-type calcium channels as well as the synaptic vesicle protein 2A (SV2A. Levetiracetam has nearly ideal pharmacokinetics. It is rapidly and almost completely absorbed after oral ingestion, is ‹10% protein-bound, demonstrates linear kinetics, is minimally metabolized through a pathway independent of the cytochrome P450 system, has no significant drug–drug interactions, and has a wide therapeutic index. The most common reported adverse events with levetiracetam XR were somnolence, irritability, dizziness, nausea, influenza, and nasopharyngitis. Levetiracetam XR provides an efficacious and well-tolerated treatment option for adjunctive therapy in the treatment of partial-onset seizures.Keywords: levetiracetam, partial-onset seizures, antiepileptic drugs

Retinal reperfusion in diabetic retinopathy following treatment with anti-VEGF intravitreal injections

Directory of Open Access Journals (Sweden)

Levin AM

2017-01-01

Full Text Available Ariana M Levin, Irene Rusu, Anton Orlin, Mrinali P Gupta, Peter Coombs, Donald J D’Amico, Szilárd Kiss Department of Ophthalmology, Weill Cornell Medical College, New York, NY, USA Purpose: The aim of this study is to report peripheral reperfusion of ischemic areas of the retina on ultra-widefield fluorescein angiography (UWFA following anti-vascular endothelial growth factor (VEGF intravitreal injections in patients treated for diabetic retinopathy. Methods: This study is a retrospective review of 16 eyes of 15 patients with diabetic retinopathy, who received anti-VEGF intravitreal injections and underwent pre- and postinjection UWFA. The main outcome measured was the presence of reperfusion in postinjection UWFA images in areas of the retina that demonstrated nonperfusion in preinjection images. Images were analyzed for reperfusion qualitatively and quantitatively by two graders. Results: Twelve of 16 eyes (75% or 11 of 15 patients (73.3% demonstrated reperfusion following anti-VEGF injection. On UWFA, reperfusion was detected both within the field of 7-standard field (7SF fluorescein angiography and in the periphery outside the 7SF. Four of 16 eyes or 4 of 15 patients did not demonstrate reperfusion, one of which had extensive scarring from prior panretinal photocoagulation. Conclusion: In patients with diabetic retinopathy, treatment with anti-VEGF agents can be associated with reperfusion of areas of nonperfusion, as demonstrated by UWFA. Keywords: anti-VEGF, diabetes, diabetic retinopathy, ischemia, perfusion, reperfusion

Isolation of a halophilic bacterium, Bacillus sp. strain NY-6 for organic contaminants removal in saline wastewater on ship

Science.gov (United States)

Gao, Jie; Yu, Zhenjiang; Zhang, Xiaohui; Zhao, Dan; Zhao, Fangbo

2013-06-01

The objective of this research was to examine if certain strains of Bacillus bacteria, could survive in dry powder products and if so, could the bacteria degrade organic contaminants in saline wastewater on a ship. As part of the study, we isolated 7 domesticated strains named NY1, NY2,..., and NY7, the strain NY6 showed to have the best performance for organic matter degradation and could survive in dry powder more than 3 months. NY6 was identified as Bacillus aerius, based on the morphological and physic-chemical properties. Its optimal growth conditions were as follows: salinity was 2%; temperature was 37°C; pH was in 6.5-7.0; best ratio of C: N: P was 100:5:1. The capability of its dry powder for Chemical Oxygen Demand (COD) removal was 800mg COD/g in synthesized marine wastewater with 2% salinity. The spores in the dry powder were 1.972×108 g -1.

Reintroduction of Lake Sturgeon (Acipenser fulvescens) into the St. Regis River, NY: Post-release assessment of habitat use and growth

Science.gov (United States)

Dittman, Dawn E.; Chalupnicki, Marc A.; Johnson, James H.; Snyder, James

2015-01-01

One of the depleted endemic fish species of the Great Lakes, Acipenser fulvescens (Lake Sturgeon), has been the target of extensive conservation efforts. One strategy is reintroduction into historically productive waters. The St. Regis River, NY, represents one such adaptive-management effort, with shared management between New York and the St. Regis Mohawk Tribe. Between 1998 and 2004, a total of 4977 young-of-year Lake Sturgeon were released. Adaptive management requires intermediate progress metrics. During 2004 and 2005, we measured growth, habitat use, and survivorship metrics of the released fish. We captured a total of 95 individuals of all stocked ages. Year-class minimal-survival rates ranged from 0.19–2.1%. The size-at-age and length/biomass relationships were comparable to those reported for juveniles in other Great Lakes waters. These intermediate assessment metrics can provide feedback to resource managers who make restoration-program decisions on a much shorter time-scale than the time-frame in which the ultimate goal of a self-sustaining population can be attained.

Ketofol for monitored anesthesia care in shoulder arthroscopy and labral repair: a case report

OpenAIRE

Lee, Kevin C; Shi, Hanyuan; Lee, Brian C

2016-01-01

Kevin C Lee,1 Hanyuan Shi,2 Brian C Lee3 1Columbia University College of Dental Medicine, New York, NY, 2Vanderbilt University School of Medicine, Nashville, TN, 3Department of Anesthesiology, Columbia University Medical Center, New York, NY, USA Abstract: A 21-year-old male (body mass index: 28.3) with a history of asthma and reactive airway disease since childhood underwent left shoulder arthroscopy and labral repair surgery under monitored anesthesia care. Because the procedure was perform...

Schizophrenia relapse after stopping olanzapine treatment during pregnancy: a case report

OpenAIRE

Ifteni, Petru; Moga, Marius A; Burtea, Victoria; Correll, Christoph U

2014-01-01

Petru Ifteni,1,2 Marius A Moga,1 Victoria Burtea,1,2 Christoph U Correll3,4 1Faculty of Medicine, Transilvania University, Brasov, Romania; 2Psychiatry and Neurology Hospital, Brasov, Romania; 3Department of Psychiatry, The Zucker Hillside Hospital, North Shore-Long Island Jewish (LIJ) Health System, New York, NY, USA; 4Hofstra North Shore-LIJ School of Medicine, New York, NY, USA Abstract: Women with schizophrenia have a high risk for symptom exacerbation or relapse during pregnan...

33 CFR 165.162 - Safety Zone: New York Super Boat Race, Hudson River, New York.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety Zone: New York Super Boat Race, Hudson River, New York. 165.162 Section 165.162 Navigation and Navigable Waters COAST GUARD... § 165.162 Safety Zone: New York Super Boat Race, Hudson River, New York. (a) Regulated area. The...

41 CFR 105-60.303 - Rules for public inspection and copying.

Science.gov (United States)

2010-07-01

..., New York, the Commonwealth of Puerto Rico, and the Virgin Islands) General Services Administration (2AR) 26 Federal Plaza, New York, NY 10278 Telephone: 212-264-1234 FAX: 212-264-2760 Mid-Atlantic...

Comparing MODIS-Terra and GOES surface albedo for New York City NY, Baltimore MD and Washington DC for 2005

Science.gov (United States)

Mubenga, K.; Hoff, R.; McCann, K.; Chu, A.; Prados, A.

2006-05-01

The NOAA GOES Aerosol and Smoke Product (GASP) is a product displaying the Aerosol Optical Depth (AOD) over the United States. The GASP retrieval involves discriminating the upwelling radiance from the atmosphere from that of the variable underlying surface. Unlike other sensors with more visible and near- infrared spectral channels such as MODIS, the sensors on GOES 8 through 12 only have one visible and a several far infrared channels. The GASP algorithm uses the detection of the second-darkest pixel from the visible channel over a 28-day period as the reference from which a radiance look-up table gives the corresponding AOD. GASP is reliable in capturing the AOD during large events. As an example, GASP was able to precisely show the Alaska and British Columbia smoke plume advecting from Alaska to the northeastern U.S. during the summer of 2004. Knapp et al. (2005) has shown that the AOD retrieval for GOES- 8 is within +/-0.13 of AERONET ground data with a coefficient of correlation of 0.72. Prados (this meeting) will update that study. However, GASP may not be as reliable when it comes to observing smaller AOD events in the northeast where the surface brightness is relatively high. The presence of large cities, such as New York, increases the surface albedo and produces a bright background against which it may be difficult to deduce the AOD. The Moderate Resolution Imaging Spectroradiometer (MODIS) sensor on the Earth Observing System Terra and Aqua platforms provides an independent measurement of the surface albedo at a resolution greater than available on GOES. In this research, the MODIS and GOES surface albedo product for New York, Washington and Baltimore are compared in order to see how we can improve the AOD retrieval in urban areas for air quality applications. Ref: K. Knapp et al. 2005. Toward aerosol optical depth retrievals over land from GOES visible radiances: determining surface reflectance. Int.Journal of Remote Sensing 26, 4097-4116

Ny forskning: Derfor virker ros ikke mod stress

DEFF Research Database (Denmark)

Pedersen, Pernille

2015-01-01

Ny forskning peger på, at stressede medarbejdere overhører din ros og anerkendelse, hvis de føler skam. Skam over ikke at kunne slå til på arbejdet. Vil du hjælpe en stresset medarbejder, skal du forebygge, at de føler sig skamfulde. Læs her anbefalinger til, hvordan du bedst hjælper din stressed...

Characterization of newly established colorectal cancer cell lines ...

Indian Academy of Sciences (India)

Unknown

2000-12-19

Dec 19, 2000 ... ... Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA .... with biotinylated horse anti-mouse IgG (Vector Labora- ...... development of new therapies or prognosis of the disease,.

Alternative vehicles and infrastructure requirements conference.

Science.gov (United States)

2011-11-01

"A conference entitled Alternative Fuel / Advanced Vehicles Technologies & Infrastructure Requirements: Bringing Innovation to Our Streets was held in New York, NY at New York University on June 14, 2011. The conference addressed several of the...

Risk and vulnerability to global and climate change in South Africa

CSIR Research Space (South Africa)

Mambo, Julia

2017-12-01

Full Text Available of working group II to the fifth assessment report of the Intergovernmental Panel on Climate Change [C.B. Field, V. Barros, D.J. Dokken, K.J. Mach, M.D. Mastrandrea, T.E. Bilir et al. (eds)]. Cambridge, UK and New York, NY: Cambridge University Press.... Qin, Z. Manning, Z. Chen, M. Marquis, K. Averyt et al. (eds)]. Cambridge, UK and New York, NY: Cambridge University Press. IPCC (Intergovernmental Panel on Climate Change). 2012. Managing the risks of extreme events and disasters to advance...

Identification of a Gypsy SHOX mutation (p.A170P) in Léri-Weill dyschondrosteosis and Langer mesomelic dysplasia.

Science.gov (United States)

Barca-Tierno, Verónica; Aza-Carmona, Miriam; Barroso, Eva; Heine-Suner, Damia; Azmanov, Dimitar; Rosell, Jordi; Ezquieta, Begoña; Montané, Lucia Sentchordi; Vendrell, Teresa; Cruz, Jaime; Santos, Fernando; Rodríguez, José Ignacio; Pozo, Jesús; Argente, Jesús; Kalaydjieva, Luba; Gracía, Ricardo; Campos-Barros, Angel; Benito-Sanz, Sara; Heath, Karen E

2011-12-01

We report the clinical and molecular characteristics of 12 Spanish families with multiple members affected with Léri-Weill dyschondrosteosis (LWD) or Langer mesomelic dysplasia (LMD), who present the SHOX (short stature homeobox gene) mutation p.A170P (c.508G>C) in heterozygosity or homozygosity, respectively. In all studied families, the A170P mutation co-segregated with the fully penetrant phenotype of mesomelic limb shortening and Madelung deformity. A shared haplotype around SHOX was observed by microsatellite analysis, confirming the presence of a common ancestor, probably of Gypsy origin, as 11 of the families were of this ethnic group. Mutation screening in 359 Eastern-European Gypsies failed to identify any carriers. For the first time, we have shown SHOX expression in the human growth plate of a 22-week LMD fetus, homozygous for the A170P mutation. Although the mutant SHOX protein was expressed in all zones of the growth plate, the chondrocyte columns in the proliferative zone were disorganized with the chondrocytes occurring in smaller columnal clusters. We have also identified a novel mutation at the same residue, c. 509C>A (p.A170D), in two unrelated Spanish LWD families, which similar to A170P mutation impedes nuclear localization of SHOX. In conclusion, we have identified A170P as the first frequent SHOX mutation in Gypsy LWD and LMD individuals.

Preferential expression of NY-BR-1 and GATA-3 in male breast cancer.

Science.gov (United States)

Biserni, Giovanni Battista; Di Oto, Enrico; Moskovszky, Linda Eszter; Foschini, Maria Pia; Varga, Zsuzsanna

2018-02-01

Male breast cancer is an uncommon disease often discovered in advanced stage; thus, in the setting of metastatic adenocarcinoma, breast origin must be taken to account. Breast markers as NY-BR-1, GATA-3, mammaglobin, and BRST-2 are established tools for labelling primary and metastatic female breast cancer; however, none of them has been sufficiently studied in male breast cancer. The aim of this study was to analyze the expression of these markers in male breast cancer. Thirty consecutive cases of male breast cancer and eight loco-regional metastases were re-revaluated, assembled in tissue micro array (TMA), and stained with immunohistochemistry (IHC) for NY-BR-1, GATA-3, mammaglobin, and BRST-2. The IHC stains were scored either positive or negative. In addition, concordant expression patterns of primary tumors and matched metastasis were noted. 30 of 30 (100%) primary tumors and 8 of 8 (100%) metastases were positive for NY-BR-1. 30 of 30 (100%) primary tumors and 6 of 8 (75%) metastases were positive for GATA-3. 22 of 30 (73.3%) primary tumors and 6 of 8 (75%) metastases were positive for Mammaglobin. 18 of 30 (60%) primary tumors and 5 of 8 (62.5%) metastases were positive for BRST-2. Differences in staining percentage were not significant with Fisher's exact test. We found a high sensitivity for all the markers analyzed. Moreover, the expression of NY-BR-1 and GATA-3 seemed the most effective for labelling male breast cancer in primary and metastatic setting.

Varadhan, Prof. Srinivasa S R

Indian Academy of Sciences (India)

Varadhan, Prof. Srinivasa S R . Date of birth: 2 January 1940. Address: Department of Mathematics, Courant Institute, New York University, 251, Mercer Street, New York, NY 10012, U.S.A.. Contact: Office: (+1-212) 982 9883

Værktøjskasse til Agil Stage-Gate®: Ny model for udviklingsprojekter i mellemstore virksomheder

DEFF Research Database (Denmark)

Vedsmand, Tomas; Edwards, Kasper; Hvidt, Nicoline

Denne værktøjskasse er et tillæg for guiden Agil Stage-Gate: Ny model for udviklingsprojekter i mellemstore virksomheder. (http://dx.doi.org/10.11581/DTU:00000028)......Denne værktøjskasse er et tillæg for guiden Agil Stage-Gate: Ny model for udviklingsprojekter i mellemstore virksomheder. (http://dx.doi.org/10.11581/DTU:00000028)...

Immunohistochemical assessment of NY-ESO-1 expression in esophageal adenocarcinoma resection specimens.

Science.gov (United States)

Hayes, Stephen J; Hng, Keng Ngee; Clark, Peter; Thistlethwaite, Fiona; Hawkins, Robert E; Ang, Yeng

2014-04-14

To assess NY-ESO-1 expression in a cohort of esophageal adenocarcinomas. A retrospective search of our tissue archive for esophageal resection specimens containing esophageal adenocarcinoma was performed, for cases which had previously been reported for diagnostic purposes, using the systematised nomenclature of human and veterinary medicine coding system. Original haematoxylin and eosin stained sections were reviewed, using light microscopy, to confirm classification and tumour differentiation. A total of 27 adenocarcinoma resection specimens were then assessed using immunohistochemistry for NY-ESO-1 expression: 4 well differentiated, 14 moderately differentiated, 4 moderate-poorly differentiated, and 5 poorly differentiated. Four out of a total of 27 cases of esophageal adenocarcinoma examined (15%) displayed diffuse cytoplasmic and nuclear expression for NY-ESO-1. They displayed a heterogeneous and mosaic-type pattern of diffuse staining. Diffuse cytoplasmic staining was not identified in any of these structures: stroma, normal squamous epithelium, normal submucosal gland and duct, Barrett's esophagus (goblet cell), Barrett's esophagus (non-goblet cell) and high grade glandular dysplasia. All adenocarcinomas showed an unexpected dot-type pattern of staining at nuclear, paranuclear and cytoplasmic locations. Similar dot-type staining, with varying frequency and size of dots, was observed on examination of Barrett's metaplasia, esophageal submucosal gland acini and the large bowel negative control, predominantly at the crypt base. Furthermore, a prominent pattern of apical (luminal) cytoplasmic dot-type staining was observed in some cases of Barrett's metaplasia and also adenocarcinoma. A further morphological finding of interest was noted on examination of haematoxylin and eosin stained sections, as aggregates of lymphocytes were consistently noted to surround submucosal glands. We have demonstrated for the first time NY-ESO-1 expression by esophageal

NOAA Office for Coastal Management Benthic Habitat Data, Long Island Sound, Jamaica Bay, and Lower Bay of NY/NJ Harbor, NY, 1994-2002 (NODC Accession 0089467)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — These data are a collection of benthic habitat data from studies conducted in the coastal Long Island Sound, NY region in GIS shapefile (.shp, .dbf, .shx, and .prj...

The transformative potential of geothermal heating in the U.S. energy market: A regional study of New York and Pennsylvania

International Nuclear Information System (INIS)

Reber, Timothy J.; Beckers, Koenraad F.; Tester, Jefferson W.

2014-01-01

Enhanced Geothermal Systems (EGS) could supply a significant fraction of the low-temperature (<125 °C) thermal energy used in the United States through Geothermal District Heating (GDH). In this study we develop a regional model to evaluate the potential for EGS district heating in the states of New York and Pennsylvania by simulating an EGS district heating network at each population center within the study region and estimating the levelized cost of heat (LCOH) from GDH for each community. LCOHs were then compiled into a supply curve from which several conclusions could be drawn. Our evaluation revealed that EGS district heating has the potential to supply cost-effective energy for space and water heating in several New York and Pennsylvania communities in the near future. To realize wider deployment, modest improvements in EGS technology, escalation of natural gas prices, and/or government incentives will likely be required to enable GDH to compete with other heating alternatives today. EGS reservoir flow rates, drilling costs, system lifetimes, and fluid return temperatures have significant effects on the LCOH of GDH and thus will provide the highest return on R and D investment, while creative implementation strategies can help EGS district heating overcome initial cost barriers that exist today. - Highlights: • EGS district heating potential evaluated for 2894 towns in New York and Pennsylvania. • Supply curves developed using estimated levelized cost of heat (LCOH) for each town. • Geothermal district heating has cost-saving potential in NY, PA and the US. • Initial candidate communities, R and D targets, and deployment strategies identified

Identification of the first de novo PAR1 deletion downstream of SHOX in an individual diagnosed with Léri-Weill dyschondrosteosis (LWD).

Science.gov (United States)

Barroso, Eva; Benito-Sanz, Sara; Belinchón, Alberta; Yuste-Checa, Patricia; Gracia, Ricardo; Aragones, Angel; Campos-Barros, Angel; Heath, Karen E

2010-01-01

Léri-Weill dyschondrosteosis (LWD, MIM 127300), is a dominantly inherited skeletal dysplasia with disproportionate short stature, mesomelic limb shortening, and the characteristic Madelung deformity. Two regions of the pseudoautosomal region 1 (PAR1) have been shown to be involved in LWD, SHOX (short-stature homeobox-containing gene) and the downstream enhancer region. We report our genetic findings of a young girl clinically diagnosed with LWD. We analyzed the proband and her family using MLPA and microsatellite analysis. We identified a deletion, 726-866 kb in size, of the downstream SHOX enhancer region in the proband. Neither parent carried the deletion. Microsatellite analysis showed that the deleted allele was of paternal origin. The mutation is more likely to have arisen from a de novo event but paternal gonadal mosaicism cannot be excluded. In conclusion, we report the clinical and molecular details of the first case of a de novo deletion of the downstream PAR1 region in an LWD individual. De novo deletions of SHOX and the downstream enhancer region must be therefore considered in cases of isolated LWD. Copyright 2010 Elsevier Masson SAS. All rights reserved.

78 FR 62293 - Safety Zone, Oyster Festival 30th Anniversary Fireworks Display, Oyster Bay; Oyster Bay, NY

Science.gov (United States)

2013-10-15

... Safety Zone, Oyster Festival 30th Anniversary Fireworks Display, Oyster Bay; Oyster Bay, NY AGENCY: Coast... zone on the navigable waters of Oyster Bay near Oyster Bay, NY for the Oyster Festival 30th Anniversary... Oyster Festival 30th Anniversary Fireworks Display is scheduled for October 19, 2013 and is one of...

Management of type 2 diabetes mellitus in the elderly: role of the pharmacist in a multidisciplinary health care team

Directory of Open Access Journals (Sweden)

Grossman S

2011-05-01

Full Text Available Samuel GrossmanDepartment of Veterans Affairs, New York Harbor Healthcare System, New York, NY, USA; Diabetes Care On-The-Go Inc, Brooklyn, NY, USA; Hunter-Bellevue School of Nursing, Hunter College, City University of New York, New York, NY, USA; Arnold and Marie Schwartz College of Pharmacy of Long Island University, Brooklyn, NY, USA; Garden State Association of Diabetes Educators, Edison, NJ, USAAbstract: Intensive glycemic control using insulin therapy may be appropriate for many healthy older adults to reduce premature mortality and morbidity, improve quality of life, and reduce health care costs. However, frail elderly people are more prone to develop complications from hypoglycemia, such as confusion and dementia. Overall, older persons with type 2 diabetes mellitus are at greater risk of death from cardiovascular disease (CVD than from intermittent hyperglycemia; therefore, diabetes management should always include CVD prevention and treatment in this patient population. Pharmacists can provide a comprehensive medication review with subsequent recommendations to individualize therapy based on medical and cognitive status. As part of the patient’s health care team, pharmacists can provide continuity of care and communication with other members of the patient’s health care team. In addition, pharmacists can act as educators and patient advocates and establish patient-specific goals to increase medication effectiveness, adherence to a medication regimen, and minimize the likelihood of adverse events.Keywords: glycemic control, hyperglycemia, continuity of care, hypertension and cardiovascular disease, elderly, type 2 diabetes, pharmacist

From single-site tantalum complexes to nanoparticles of TaxNy and TaOxNy supported on silica: elucidation of synthesis chemistry by dynamic nuclear polarization surface enhanced NMR spectroscopy and X-ray absorption spectroscopy

KAUST Repository

Mohandas, Janet Chakkamadathil

2017-06-08

Air-stable catalysts consisting of tantalum nitride nanoparticles represented as a mixture of TaxNy and TaOxNy with diameters in the range of 0.5 to 3 nm supported on highly dehydroxylated silica were synthesized from TaMe5 (Me = methyl) and dimeric Ta-2(OMe)(10) with guidance by the principles of surface organometallic chemistry (SOMC). Characterization of the supported precursors and the supported nanoparticles formed from them was carried out by IR, NMR, UV-Vis, extended X-ray absorption fine structure, and X-ray photoelectron spectroscopies complemented with XRD and high-resolution TEM, with dynamic nuclear polarization surface enhanced NMR spectroscopy being especially helpful by providing enhanced intensities of the signals of H-1, C-13, Si-29, and N-15 at their natural abundances. The characterization data provide details of the synthesis chemistry, including evidence of (a) O-2 insertion into Ta-CH3 species on the support and (b) a binuclear to mononuclear transformation of species formed from Ta-2(OMe)(10) on the support. A catalytic test reaction, cyclooctene epoxidation, was used to probe the supported nanoparticles, with 30% H2O2 serving as the oxidant. The catalysts gave selectivities up to 98% for the epoxide at conversions as high as 99% with a 3.4 wt% loading of Ta present as TaxNy/TaOxNy.

Depression in Parkinson’s disease: Health risks, etiology, and treatment options

Directory of Open Access Journals (Sweden)

Pasquale G Frisina

2008-03-01

Full Text Available Pasquale G Frisina1,2, Joan C Borod3,4, Nancy S Foldi3,5, Harriet R Tenenbaum61Leir Parkinson’s Disease Program, The Jewish Home and Hospital Lifecare System, New York, NY, USA; 2Department of Geriatrics and Adult Development, Mount Sinai School of Medicine, New York, NY, USA; 3Department of Psychology, Queens College and The Graduate Center of the City University of New York (CUNY, Flushing, NY, USA; 4Department of Neurology, Mount Sinai School of Medicine, New York, NY, USA; 5Department of Medicine, Winthrop-University Hospital, State University of New York, Stony Brook School of Medicine; 6Department of Psychology, Kingston University, Kingston upon Thames, UKAbstract: Depression is found in about 30%–40% of all patients with Parkinson’s disease (PD, but only a small percentage (about 20% receive treatment. As a consequence, many PD patients suffer with reduced health-related quality of life. To address quality of life in depressed PD patients, we reviewed the literature on the health correlates of depression in PD (eg, cognitive function, etiology of depression in PD, and treatment options (ie, antidepressants, electroconvulsive therapy, and psychotherapy. The current review is unique in its focus on psychosocial aspects, as well as neuropathological factors, of depression in PD. Overall, we conclude that neurochemical (eg, serotonin and psychosocial factors (eg, coping style, self-esteem, and social support contribute to the affective disturbances found in this neuropsychiatric population. Therefore, we recommend that a multidisciplinary (eg, pharmacotherapeutic, psychoeducational, and/or psychotherapeutic approach to treatment be taken with depressed PD patients.Keywords: depression, Parkinson’s disease, health outcomes, treatment options

78 FR 37456 - Drawbridge Operation Regulations; Reynolds Channel, Nassau, NY

Science.gov (United States)

2013-06-21

... Regulations; Reynolds Channel, Nassau, NY AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from... regulation governing the operation of the Long Beach Bridge, mile 4.7, across Reynolds Channel at Nassau, New... July 1, 2013. Reynolds Creek has commercial and recreational vessel traffic. No objections were...

Reynolds Metals Company, Massena, NY

Science.gov (United States)

The 1,600-acre former Reynolds Metals Facility is located on the St. Lawrence River, approximately eight miles east of the Village of Massena, New York. The facility, which was constructed in 1958 for the production of aluminum, closed in 2014. It is owned

Liberating primatology

Indian Academy of Sciences (India)

SINDHU RADHAKRISHNA1 2 DALE JAMIESON2. School of Natural Sciences and Engineering, National Institute of Advanced Studies, Indian Institute of Science Campus, Bengaluru 560 012, India; Environmental Studies Department, New York University, New York, NY 10003-6653, USA ...

Research Article. A new gravity laboratory in Ny-Ålesund, Svalbard

Directory of Open Access Journals (Sweden)

Breili K.

2017-02-01

Full Text Available The Norwegian Mapping Authority (NMA has recently established a new gravity laboratory in Ny-Ålesund at Svalbard, Norway. The laboratory consists of three independent pillars and is part of the geodetic core station that is presently under construction at Brandal, approximately 1.5 km north of NMA’s old station. In anticipation of future use of the new gravity laboratory, we present benchmark gravity values, gravity gradients, and final coordinates of all new pillars. Test measurements indicate a higher noise level at Brandal compared to the old station. The increased noise level is attributed to higher sensitivity to wind.We have also investigated possible consequences of moving to Brandal when it comes to the gravitational signal of present-day ice mass changes and ocean tide loading. Plausible models representing ice mass changes at the Svalbard archipelago indicate that the gravitational signal at Brandal may differ from that at the old site with a size detectable with modern gravimeters. Users of gravity data from Ny-Ålesund should, therefore, be cautious if future observations from the new observatory are used to extend the existing gravity record. Due to its lower elevation, Brandal is significantly less sensitive to gravitational ocean tide loading. In the future, Brandal will be the prime site for gravimetry in Ny-Ålesund. This ensures gravity measurements collocated with space geodetic techniques like VLBI, SLR, and GNSS.

78 FR 26508 - Drawbridge Operation Regulations; Reynolds Channel, Nassau, NY

Science.gov (United States)

2013-05-07

... Regulations; Reynolds Channel, Nassau, NY AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from... regulation governing the operation of the Long Beach Bridge, mile 4.7, across Reynolds Channel at Nassau, New.... on July 12, 2013. Reynolds Creek has commercial and recreational vessel traffic. No objections were...

Portrayal of the Geosciences in the New York Times

Science.gov (United States)

Wysession, M. E.; Lindstrom, A.

2017-12-01

An analysis of the portrayal of science, including the geosciences, in the New York Times shows that geoscience topics dominate front-page science coverage, appearing significantly more often than articles concerning biology, chemistry, or physics. This is significant because the geosciences are sometimes portrayed (in most high schools, for example) as being of less significance or importance than the other sciences, yet their portrayal in what is arguably the leading U.S. newspaper shows just the opposite - that the geosciences are the most relevant and newsworthy of the sciences. We analyzed NY Times front pages and Tuesday "Science Times" sections for 2012 - 2015, and looked at many parameters including science discipline, the kind of article (research, policy, human-interest, etc.), correlations to the "big ideas" of the Next Generation Science Standards, and for the geosciences, a break-down of sub-disciplines. For the front pages, we looked at both full articles and call-outs to articles on later pages. For front-page full articles, geoscience-related articles were more frequent (almost 60%) than biology, chemistry, and physics combined. Including call-outs to later articles, the geosciences still made the most front-page appearances (almost 40%), and this included the fact that 1/3 of front-page science articles were medicine-related, which accounted for nearly all of the biology and chemistry articles. Interestingly, what the NY Times perceived as "science" differed significantly: 60% of all Tuesday "Science Times" articles were medicine-related, and even removing these, biology (40%) edged the geosciences (35%) as the most frequent Science Times articles. Of the front-page geoscience articles, the topics were dominated each year by natural hazards, natural resources, and human impacts, with the percentage of human-impact-related articles almost doubling over the 4 years. The most significant 4-year trend was in the attention paid to climate change. For

The Snackbot: Documenting the Design of a Robot for Long-term Human-Robot Interaction

Science.gov (United States)

2009-03-01

distributed robots. Proceedings of the Computer Supported Cooperative Work Conference’02. NY: ACM Press. [18] Kanda, T., Takayuki , H., Eaton, D., and...humanoid robots. Proceedings of HRI’06. New York, NY: ACM Press, 351-352. [23] Nabe, S., Kanda, T., Hiraki , K., Ishiguro, H., Kogure, K., and Hagita

Measurement of serum antibodies against NY-ESO-1 by ELISA: A guide for the treatment of specific immunotherapy for patients with advanced colorectal cancer.

Science.gov (United States)

Long, Yan-Yan; Wang, Yu; Huang, Qian-Rong; Zheng, Guang-Shun; Jiao, Shun-Chang

2014-10-01

NY-ESO-1 has been identified as one of the most immunogenic antigens; thus, is a highly attractive target for cancer immunotherapy. The present study analyzed the expression of serum antibodies (Abs) against NY-ESO-1 in patients with advanced colorectal cancer (CRC), with the aim of guiding the treatment of NY-ESO-1-based specific-immunotherapy for these patients. Furthermore, the present study was the first to evaluate the kinetic expression of anti-NY-ESO-1 Abs and investigate the possible influencing factors. A total of 239 serum samples from 155 pathologically confirmed patients with advanced CRC (stages III and IV) were collected. The presence of spontaneous Abs against NY-ESO-1 was analyzed using an enzyme-linked immunosorbent assay (ELISA). The results demonstrated that 24.5% (38/155) of the investigated patients were positive for NY-ESO-1-specific Abs. No statistically significant correlations were identified between the expression of anti-NY-ESO-1 Abs and clinicopathological parameters, including age and gender, location, grading, local infiltration, lymph node status, metastatic status and K-ras mutation status (P>0.05). In 59 patients, the kinetic expression of anti-NY-ESO-1 Abs was analyzed, of which 14 patients were initially positive and 45 patients were initially negative. Notably, 16/59 (27.1%) patients changed their expression status during the study period, and the initially positive patients were more likely to change compared with the initially negative patients (85.7 vs. 8.8%; Pguide the treatment of NY-ESO-1-based specific immunotherapy for patients with advanced CRC.

Sjøforsvaret i ny drakt

DEFF Research Database (Denmark)

Vestvik, Marit; Bjerck, Mari

Denne rapporten formidler resultater fra undersøkelser som er gjort på to av Sjøforsvarets fartøy i 2010 og 2011, som omfatter utprøving av ny niformsmodell for utendørs bruk. Undersøkelsene er en del av forskningsprosjektet Uni-Form: Arbeidsbekledning for kvinner i mannsdominerte yrker. I...... prosjektet utvikles arbeidsklær for Sjøforsvarets personell som har bedre funksjonalitet og komfort enn eksisterende uniformer. En målsetning er å bedre trivselen for personellet gjennom å utvikle forbedrete uniformbekledning. At uniformsbekledningen er tilfredsstillende i funksjonalitet, passform og...... tilpasset snitt for kvinner. Dette gjelder også Forsvarets uniformer....

Recombinant Lactobacillus plantarum induces immune responses to cancer testis antigen NY-ESO-1 and maturation of dendritic cells

Science.gov (United States)

Mobergslien, Anne; Vasovic, Vlada; Mathiesen, Geir; Fredriksen, Lasse; Westby, Phuong; Eijsink, Vincent GH; Peng, Qian; Sioud, Mouldy

2015-01-01

Given their safe use in humans and inherent adjuvanticity, Lactic Acid Bacteria may offer several advantages over other mucosal delivery strategies for cancer vaccines. The objective of this study is to evaluate the immune responses in mice after oral immunization with Lactobacillus (L) plantarum WCFS1 expressing a cell-wall anchored tumor antigen NY-ESO-1. And to investigate the immunostimulatory potency of this new candidate vaccine on human dendritic cells (DCs). L. plantarum displaying NY-ESO-1 induced NY-ESO-1 specific antibodies and T-cell responses in mice. By contrast, L. plantarum displaying conserved proteins such as heat shock protein-27 and galectin-1, did not induce immunity, suggesting that immune tolerance to self-proteins cannot be broken by oral administration of L. plantarum. With respect to immunomodulation, immature DCs incubated with wild type or L. plantarum-NY-ESO-1 upregulated the expression of co-stimulatory molecules and secreted a large amount of interleukin (IL)-12, TNF-α, but not IL-4. Moreover, they upregulated the expression of immunosuppressive factors such as IL-10 and indoleamine 2,3-dioxygenase. Although L. plantarum-matured DCs expressed inhibitory molecules, they stimulated allogeneic T cells in-vitro. Collectively, the data indicate that L. plantarum-NY-ESO-1 can evoke antigen-specific immunity upon oral administration and induce DC maturation, raising the potential of its use in cancer immunotherapies. PMID:26185907

NOAA Digital Orthophotography for the Coasts of Connecticut and Long Island, NY

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Project: NOAA Digital Orthophotography for the Coasts of Main/New Hampshire, Massachusetts/Rhode Island/Connecticut, and Hudson River/Long Island /NY/NJ Contract No....

76 FR 4078 - Television Broadcasting Services; North Pole and Plattsburgh, NY

Science.gov (United States)

2011-01-24

... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [DA 10-2443; MM Docket No. 99-238; RM-9669] Television Broadcasting Services; North Pole and Plattsburgh, NY AGENCY: Federal Communications Commission... CFR Part 73 Television, Television broadcasting. For the reasons discussed in the preamble, the...

Physical and Chemical Properties of TiOxNy Prepared by Low-Temperature Oxidation of Ultrathin Metal Nitride Directly Deposited on SiO2

Institute of Scientific and Technical Information of China (English)

HAN Yue-Ping; HAN Yan

2009-01-01

Physical and chemical properties of titanium oxynitride (TiOxNy) formed by low-temperature oxidation of titanium nitride (TIN) layer are investigated for advanced metal-oxide--semiconductor (MOS) gate dielectric application.TiOx Ny exhibits polycrystalline properties after the standard thermal process for MOS device fabrication,showing the preferred orientation at [200].Superior electrical properties of TiOxNy can be maintained before and after the annealing,probably due to the nitrogen incorporation in the oxide bulk and at the interface.Naturally formed transition layer between TiOxNy and SiO2 is also confirmed.

Resonance – Journal of Science Education | Indian Academy of ...

Indian Academy of Sciences (India)

David L Farrens1 Thomas P Sakmar2. Department of Biochemistry and Molecular Biology Oregon Health and Science University Portland OR 97239, USA. Head, Laboratory of Chemical Biology and Signal Transduction The Rockefeller University, 1230 York, Ave., New York, NY 10065, USA.

Excessive daytime sleepiness and adherence to antihypertensive medications among Blacks: analysis of the counseling African Americans to control hypertension (CAATCH trial

Directory of Open Access Journals (Sweden)

Williams NJ

2014-03-01

Full Text Available Natasha J Williams,1 Girardin Jean-Louis,1 Abhishek Pandey,2 Joseph Ravenell,1 Carla Boutin-Foster,3 Gbenga Ogedegbe1 1Center for Healthful Behavior Change, Division of Internal Medicine, NYU Medical Center, New York, 2Department of Family Medicine, SUNY Downstate Medical Center, Brooklyn, 3Center of Excellence in Disparities Research, Weill Cornell Medical College, New York, NY, USA Background: Excessive daytime sleepiness (EDS often occurs as a result of insufficient sleep, sleep apnea, illicit substance use, and other medical and psychiatric conditions. This study tested the hypothesis that blacks exhibiting EDS would have poorer self-reported adherence to hypertensive medication using cross-sectional data from the Counseling African-Americans to Control Hypertension (CAATCH trial. Methods: A total of 1,058 hypertensive blacks (average age 57±12 years participated in CAATCH, a randomized controlled trial evaluating the effectiveness of a multilevel intervention for participants who receive care from community health centers in New York City. Data analyzed in this study included baseline sociodemographics, medical history, EDS, and medication adherence. We used the Epworth Sleepiness Scale, with a cutoff score of ≥10, to define EDS. Medication adherence was measured using an abbreviated Morisky Medication Adherence scale, with a score >0 indicating nonadherence. Results: Of the sample, 71% were female, 72% received at least a high school education, 51% reported a history of smoking, and 33% had a history of alcohol consumption. Overall, 27% of the participants exhibited EDS, and 44% of those who exhibited EDS were classified as adherent to prescribed antihypertensive medications. Multivariable logistic regression analysis, adjusting for effects of age, body mass index, sex, education, and smoking and drinking history indicated that participants who exhibited EDS were more than twice as likely to be nonadherent (odds ratio 2.28, 95

A community health worker intervention to improve management of hypertension among Filipino Americans in New York and New Jersey: a pilot study.

Science.gov (United States)

Ursua, Rhodora A; Aguilar, David E; Wyatt, Laura C; Katigbak, Carina; Islam, Nadia S; Tandon, S Darius; Nur, Potri Ranka Manis Queano; Van Devanter, Nancy; Rey, Mariano J; Trinh-Shevrin, Chau

2014-01-01

The purpose of the pilot study was to assess the feasibility and efficacy of a 4-month community health worker (CHW) intervention to improve hypertension management among Filipino immigrants in New York and New Jersey. Single-arm CHW pilot intervention using a pre-post design delivered by 5 CHWs. New York City, NY and Jersey City, NJ. Of 88 Filipino individuals recruited for the study, 39 received the full pilot intervention, 18 received a partial intervention, and 31 dropped out; 13 Filipino participants, 10 CHW Trainers, and 3 Filipino CHWs were interviewed for qualitative analysis. Individuals participated in 4 workshops related to hypertension management and cardiovascular disease (CVD) risk factors and received monthly in-person visits, and twice monthly phone calls individually from a CHW. Primary outcomes included blood pressure (BP) reduction and control, appointment keeping, and medication adherence; secondary outcomes included weight, body mass index (BMI), self-efficacy related to diet, exercise, and medication taking, CVD knowledge, and nutrition (salt/ sodium and cholesterol/fat). A mixed method analysis was used to assess the intervention, utilizing quantitative and qualitative methods. By the end of the intervention, significant changes were exhibited for systolic and diastolic BP, weight, and BMI (PFilipino Americans.

The York Gospels

DEFF Research Database (Denmark)

Teasdale, Matthew D.; Fiddyment, Sarah; Vnouček, Jiří

2017-01-01

Gospels (York Minster Ms. Add. 1) is one such codex, one of only a small collection of pre-conquest Gospel books to have survived the Reformation. By extending the non-invasive triboelectric (eraser-based) sampling technique eZooMS, to include the analysis of DNA, we report a cost-effective and simple......-to-use biomolecular sampling technique for parchment. We apply this combined methodology to document for the first time a rich palimpsest of biological information contained within the York Gospels, which has accumulated over the 1000-year lifespan of this cherished object that remains an active participant...... in the life of York Minster. These biological data provide insights into the decisions made in the selection of materials, the construction of the codex and the use history of the object....

New York Marcellus Shale: Industry boom put on hold

Energy Technology Data Exchange (ETDEWEB)

Mercurio, Angelique

2012-01-16

, New Mexico, North Dakota, Ohio, Oklahoma, Pennsylvania, South Dakota, Texas, Utah, West Virginia, and Wyoming are pursuing. Positive labor market impacts are another major economic draw. According to the Revised Draft SGEIS on the Oil, Gas and Solution Mining Regulatory Program (September 2011), hydraulic fracturing would create between 4,408 and 17,634 full-time equivalent (FTE) direct construction jobs in New York State. Indirect employment in other sectors would add an additional 29,174 FTE jobs. Furthermore, the SGEIS analysis suggests that drilling activities could add an estimated $621.9 million to $2.5 billion in employee earnings (direct and indirect) per year, depending upon how much of the shale is developed. The state would also receive direct tax receipts from leasing land, and has the potential to see an increase in generated indirect revenue. Estimates range from $31 million to $125 million per year in personal income tax receipts, and local governments would benefit from revenue sharing. Some landowner groups say the continued delay in drilling is costing tens of thousands of jobs and millions of dollars in growth for New York, especially in the economically stunted upstate. A number of New York counties near Pennsylvania, such as Chemung, NY, have experienced economic uptick from Pennsylvania drilling activity just across the border. Chemung officials reported that approximately 1,300 county residents are currently employed by the drilling industry in Pennsylvania. The Marcellus shale boom is expected to continue over the next decade and beyond. By 2015, gas drilling activity could bring 20,000 jobs to New York State alone. Other states, such as Pennsylvania and West Virginia, are also expected to see a significant increase in the number of jobs. Catalyst 2: Political Reality of the Moratorium. Oil and gas drilling has taken place in New York since the 19th century, and it remains an important industry with more than 13,000 currently active wells. The

77 FR 17526 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2012-03-26

... Services. 81,162 Kennametal, Inc., Greenfield, MA April 1, 2011. JSCL Division. 81,324 CSB Fashion Inc..... New York, NY February 10, 2011. 81,337 Fu Sing Fashion, Inc Brooklyn, NY February 12, 2011. 81,374... Staffing and Adecco. 81,336 Bureau Veritas, Taunton, MA February 14, 2011. Consumer Product Services, Inc...

Nearshore sediment thickness, Fire Island, New York

Science.gov (United States)

Locker, Stanley D.; Miselis, Jennifer L.; Buster, Noreen A.; Hapke, Cheryl J.; Wadman, Heidi M.; McNinch, Jesse E.; Forde, Arnell S.; Stalk, Chelsea A.

2017-04-03

Investigations of coastal change at Fire Island, New York (N.Y.), sought to characterize sediment budgets and determine geologic framework controls on coastal processes. Nearshore sediment thickness is critical for assessing coastal system sediment availability, but it is largely unquantified due to the difficulty of conducting geological or geophysical surveys across the nearshore. This study used an amphibious vessel to acquire chirp subbottom profiles. These profiles were used to characterize nearshore geology and provide an assessment of nearshore sediment volume. Two resulting sediment-thickness maps are provided: total Holocene sediment thickness and the thickness of the active shoreface. The Holocene sediment section represents deposition above the maximum flooding surface that is related to the most recent marine transgression. The active shoreface section is the uppermost Holocene sediment, which is interpreted to represent the portion of the shoreface thought to contribute to present and future coastal behavior. The sediment distribution patterns correspond to previously defined zones of erosion, accretion, and stability along the island, demonstrating the importance of sediment availability in the coastal response to storms and seasonal variability. The eastern zone has a thin nearshore sediment thickness, except for an ebb-tidal deposit at the wilderness breach caused by Hurricane Sandy. Thicker sediment is found along a central zone that includes shoreface-attached sand ridges, which is consistent with a stable or accretional coastline in this area. The thickest overall Holocene section is found in the western zone of the study, where a thicker lower section of Holocene sediment appears related to the westward migration of Fire Island Inlet over several hundred years.

Combined Arms in the Electro-Magnetic Spectrum: Integrating Non-kinetic Operations

Science.gov (United States)

2013-05-23

Greene , Robert. The 33 Strategies of War. New York: Penguin, 2007. Halpern, Jason. IP Telephony Security in Depth. Cisco Systems, 2003...Theory of John Boyd. New York, NY: Routledge, 2007. Paiget, J., & Inhelder, B. Memory and Intelligence. London: Routledge and Kegan Paul, 1973. Qiao

AlGaN/GaN High Electron Mobility Transistors with Multi-MgxNy/GaN Buffer

OpenAIRE

Chang, P. C.; Lee, K. H.; Wang, Z. H.; Chang, S. J.

2014-01-01

We report the fabrication of AlGaN/GaN high electron mobility transistors with multi-MgxNy/GaN buffer. Compared with conventional HEMT devices with a low-temperature GaN buffer, smaller gate and source-drain leakage current could be achieved with this new buffer design. Consequently, the electron mobility was larger for the proposed device due to the reduction of defect density and the corresponding improvement of crystalline quality as result of using the multi-MgxNy/GaN buffer.

Afprøvning af ny feedbackpraksis på UCN Pædagoguddannelsen

DEFF Research Database (Denmark)

Andersen, Eva; Rasmussen, Anna Ørnemose; Stenderup, Mogens Larsen

2017-01-01

I forbindelse med implementering af ny pædagoguddannelse (BEK nr 354 af 07/04/2017) har pædagoguddannelsens ledernetværk igangsat flere nationale sektorprojekter herunder projekt Feedbackformer i en kompetencestyret uddannelse. Alle projekternes formål er at understøtte udvikling og implementering...

77 FR 30451 - Safety Zone; Olcott Fireworks, Lake Ontario, Olcott, NY

Science.gov (United States)

2012-05-23

... Lake Ontario, Olcott, NY. This proposed rule is intended to restrict vessels from a portion of Lake Ontario during the Olcott fireworks display. The safety zone established by this proposed rule is necessary to protect spectators, participants, and vessels from the hazards associated with firework display...

33 CFR 207.610 - St. Lawrence River, Cape Vincent Harbor, N.Y.; use, administration, and navigation of the harbor...

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false St. Lawrence River, Cape Vincent Harbor, N.Y.; use, administration, and navigation of the harbor and U.S. breakwater. 207.610 Section 207... NAVIGATION REGULATIONS § 207.610 St. Lawrence River, Cape Vincent Harbor, N.Y.; use, administration, and...

Climatology and time series of surface meteorology in Ny-Ålesund, Svalbard

Directory of Open Access Journals (Sweden)

M. Maturilli

2013-04-01

Full Text Available A consistent meteorological dataset of the Arctic site Ny-Ålesund (11.9° E, 78.9° N spanning the 18 yr-period 1 August 1993 to 31 July 2011 is presented. Instrumentation and data handling of temperature, humidity, wind and pressure measurements are described in detail. Monthly mean values are shown for all years to illustrate the interannual variability of the different parameters. Climatological mean values are given for temperature, humidity and pressure. From the climatological dataset, we also present the time series of annual mean temperature and humidity, revealing a temperature increase of +1.35 K per decade and an increase in water vapor mixing ratio of +0.22 g kg−1 per decade for the given time period, respectively. With the continuation of the presented measurements, the Ny-Ålesund high resolution time series will provide a reliable source to monitor Arctic change and retrieve trends in the future. The relevant data are provided in high temporal resolution as averages over 5 (1 min before (after 14 July 1998, respectively, placed on the PANGAEA repository (doi:10.1594/PANGAEA.793046. While 6 hourly synoptic observations in Ny-Ålesund by the Norwegian Meteorological Institute reach back to 1974 (Førland et al., 2011, the meteorological data presented here cover a shorter time period, but their high temporal resolution will be of value for atmospheric process studies on shorter time scales.

Atmospheric black carbon concentrations in North America, ~1100 to 2005. Liaquat Husain and Tanveer Ahmed Wadsworth Center, New York State Department of Health, Albany, NY 12201-0509, USA, and Department of Environmental Health Sciences, School of Public Health, State University of New York, Albany, NY, 12201-0509, USA

Science.gov (United States)

Husain, L.

2013-05-01

Black carbon (BC) aerosols in the atmosphere absorb solar radiation, and cause heating of the atmosphere, may alter Earth's cloud cover, and impact precipitation cycle. The best estimate for radiative forcing from BC with 90% certainty is + 1.1 Wm-2 ( + 0.17 to 2.1 Wm-2), second only to that of CO2. A major uncertainty in the estimation is a lack of atmospheric BC data. Models are used to estimate BC emissions into the atmosphere. They have not been validated by field data. We report measurements of BC in the atmosphere, over a period of several centuries using lake sediments. Retrieval of such records provides an invaluable source for understanding changes in the atmosphere with time. Numerous studies have been conducted with such an objective. Owing to a lack of knowledge of deposition rates of atmospheric aerosols into the lake sediments, a major shortcoming of these studies have been an inability to convert the measurements of chemical species in lake sediments into the atmosphere. We have developed a technique to overcome this shortcoming by measuring black carbon in atmospheric aerosols, and in lake sediment cores. The concentrations of BC were determined in daily filters collected at Whiteface Mountain, NY, from 1978 to 2005. Cores from two lakes around Whiteface Mountain, NY, were collected. Cores were (1) sectioned in thin slices, (2) freeze dried, (3) dated using the 210Pb technique, (4) BC chemically separated, and (5) concentrations measured using the thermal-optical method. By The deposition rate of BC from the atmosphere to the lakes was determined by comparing the BC concentration in air and the sediments for the 1978 -2005 period. The deposition rate so determined was used to concert the BC in the sediment into the atmosphere for the ~1978 to ~1100 period. The BC concentrations for the industrial period, ~1850 was low but rapidly increased from ~1900, peaked ~1925, decreased very slowly ~ 1980, followed by a sharp decrease. Concentrations has

Contribution of Cultural Eutrophication to Marsh Loss in Jamaica Bay (NY)

Science.gov (United States)

Loss of salt marsh area in the Jamaica Bay Estuary (NY) has accelerated in recent years, with loss rates as high as 45 acres per year. A contributing factor to this acceleration is likely cultural eutrophication due to over 6 decades of sewage effluent inputs. We examined marsh...

Variation in concentrations of three mercury (Hg) forms at a rural and a suburban site in New York State.

Science.gov (United States)

Choi, Hyun-Deok; Huang, Jiaoyan; Mondal, Sumona; Holsen, Thomas M

2013-03-15

Tekran® Hg speciation systems were used at a rural site (Huntington Forest, NY; HF) and a suburban site (Rochester, NY; ROC) to measure gaseous elemental mercury (GEM), gaseous oxidized mercury (GOM), and fine particulate-bound mercury (PBM2.5) concentrations for two years (December 2007 to November 2009). Ancillary data were also available from the New York State Department of Environmental Conservation and the United States Environmental Protection Agency Clean Air Status and Trends Network. Seasonal GEM concentrations were similar at both sites and influenced by factors such as the planet boundary layer (PBL) height and mercury emissions from snow, soil, and point sources. In some seasons, O3 was negatively correlated with GEM at ROC and positively correlated with GEM at HF. At HF, O3 was correlated with GOM and was typically higher in the afternoon. The cause of this pattern may be photochemical reactions during the day, and the GOM diel pattern may also be due to deposition which is enhanced by dew formation during the night and early morning. PBM2.5 concentrations were higher in winter at both sites. This is indicative of local wood combustion for space heating in winter, increased sorption to particles at lower temperatures, and lower PBL in the winter. At the suburban site, 2 of 12 events with enhanced GEM/CO ratios were poorly correlated with SO2/GOM, implying that these two events were due either to long range transport or regional metallurgical industries in Canada. Copyright © 2012 Elsevier B.V. All rights reserved.

AlGaN/GaN High Electron Mobility Transistors with Multi-MgxNy/GaN Buffer

Directory of Open Access Journals (Sweden)

P. C. Chang

2014-01-01

Full Text Available We report the fabrication of AlGaN/GaN high electron mobility transistors with multi-MgxNy/GaN buffer. Compared with conventional HEMT devices with a low-temperature GaN buffer, smaller gate and source-drain leakage current could be achieved with this new buffer design. Consequently, the electron mobility was larger for the proposed device due to the reduction of defect density and the corresponding improvement of crystalline quality as result of using the multi-MgxNy/GaN buffer.

75 FR 51114 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-IMS Global...

Science.gov (United States)

2010-08-18

... Production Act of 1993--IMS Global Learning Consortium, Inc. Notice is hereby given that, on July 13, 2010... seq. (``the Act''), IMS Global Learning Consortium, Inc. has filed written notifications...; New York City Department of Education, New York, NY; and Ucompass.com , Inc., Tallahassee, FL, have...

The hydrogeology of the Tully Valley, Onondaga County, New York: an overview of research, 1992-2012

Science.gov (United States)

Kappel, William M.

2014-01-01

Onondaga Creek begins approximately 15 miles south of Syracuse, New York, and flows north through the Onondaga Indian Nation, then through Syracuse, and finally into Onondaga Lake in central New York. Tully Valley is in the upper part of the Onondaga Creek watershed between U.S. Route 20 and the Valley Heads end moraine near Tully, N.Y. Tully Valley has a history of several unusual hydrogeologic phenomena that affected past land use and the water quality of Onondaga Creek; the phenomena are still present and continue to affect the area today (2014). These phenomena include mud volcanoes or mudboils, landslides, and land-surface subsidence; all are considered to be naturally occurring but may also have been influenced by human activity. The U.S. Geological Survey (USGS), in cooperation with the U.S. Environmental Protection Agency and the Onondaga Lake Partnership, began a study of the Tully Valley mudboils beginning in October 1991 in hopes of understanding (1) what drives mudboil activity in order to remediate mudboil influence on the water quality of Onondaga Creek, and (2) land-surface subsidence issues that have caused a road bridge to collapse, a major pipeline to be rerouted, and threatened nearby homes. Two years into this study, the 1993 Tully Valley landslide occurred just over 1 mile northwest of the mudboils. This earth slump-mud flow was the largest landslide in New York in more than 70 years (Fickies, 1993); this event provided additional insight into the geology and hydrology of the valley. As the study of the Tully Valley mudboils progressed, other unusual hydrogeologic phenomena were found within the Tully Valley and provided the opportunity to perform short-term, small-scale studies, some of which became graduate student theses—Burgmeier (1998), Curran (1999), Morales-Muniz (2000), Baldauf (2003), Epp (2005), Hackett, (2007), Tamulonis (2010), and Sinclair (2013). The unusual geology and hydrology of the Tully Valley, having been investigated for

Resource adequacy in New York

International Nuclear Information System (INIS)

Charlton, J.W.

2004-01-01

This paper describes the electric market products in New York. The New York Installed Capacity (ICAP) market is intended to promote resource adequacy and allows suppliers to recover a portion of their fixed (capital) cost. The New York Energy market allows a supplier to recover its variable costs and to compete for profits. The Ancillary Services market allows a supplier to recover lost opportunity costs when providing ancillary services. The total revenue from these markets is the true revenue stream of a supplier

Clinical and molecular evaluation of SHOX/PAR1 duplications in Leri-Weill dyschondrosteosis (LWD) and idiopathic short stature (ISS).

Science.gov (United States)

Benito-Sanz, S; Barroso, E; Heine-Suñer, D; Hisado-Oliva, A; Romanelli, V; Rosell, J; Aragones, A; Caimari, M; Argente, J; Ross, J L; Zinn, A R; Gracia, R; Lapunzina, P; Campos-Barros, A; Heath, K E

2011-02-01

Léri-Weill dyschondrosteosis (LWD) is a skeletal dysplasia characterized by disproportionate short stature and the Madelung deformity of the forearm. SHOX mutations and pseudoautosomal region 1 deletions encompassing SHOX or its enhancers have been identified in approximately 60% of LWD and approximately 15% of idiopathic short stature (ISS) individuals. Recently SHOX duplications have been described in LWD/ISS but also in individuals with other clinical manifestations, thus questioning their pathogenicity. The objective of the study was to investigate the pathogenicity of SHOX duplications in LWD and ISS. Multiplex ligation-dependent probe amplification is routinely used in our unit to analyze for SHOX/pseudoautosomal region 1 copy number changes in LWD/ISS referrals. Quantitative PCR, microsatellite marker, and fluorescence in situ hybridization analysis were undertaken to confirm all identified duplications. During the routine analysis of 122 LWD and 613 ISS referrals, a total of four complete and 10 partial SHOX duplications or multiple copy number (n > 3) as well as one duplication of the SHOX 5' flanking region were identified in nine LWD and six ISS cases. Partial SHOX duplications appeared to have a more deleterious effect on skeletal dysplasia and height gain than complete SHOX duplications. Importantly, no increase in SHOX copy number was identified in 340 individuals with normal stature or 104 overgrowth referrals. MLPA analysis of SHOX/PAR1 led to the identification of partial and complete SHOX duplications or multiple copies associated with LWD or ISS, suggesting that they may represent an additional class of mutations implicated in the molecular etiology of these clinical entities.

SHOX gene defects and selected dysmorphic signs in patients of idiopathic short stature and Léri-Weill dyschondrosteosis.

Science.gov (United States)

Hirschfeldova, K; Solc, R; Baxova, A; Zapletalova, J; Kebrdlova, V; Gaillyova, R; Prasilova, S; Soukalova, J; Mihalova, R; Lnenicka, P; Florianova, M; Stekrova, J

2012-01-10

The aim of the study was to analyze frequency of SHOX gene defects and selected dysmorphic signs in patients of both idiopathic short stature (ISS) and Léri-Weill dyschondrosteosis (LWD), all derived from the Czech population. Overall, 98 subjects were analyzed in the study. Inclusion criteria were the presence of short stature (-2.0 SD), in combination with at least one of the selected dysmorphic signs for the ISS+ group; and the presence of Madelung deformity, without positive karyotyping for the LWD+ group. Each proband was analyzed by use of P018 MLPA kit, which covers SHOX and its regulatory sequences. Additionally, mutational analysis was done of the coding portions of the SHOX. Both extent and breakpoint localizations in the deletions/duplications found were quite variable. Some PAR1 rearrangements were detected, without obvious phenotypic association. In the ISS+ group, MLPA analysis detected four PAR1 deletions associated with a SHOX gene defect, PAR1 duplication with an ambiguous effect, and two SHOX mutations (13.7%). In the LWD+ group, MLPA analysis detected nine deletions in PAR1 region, with a deleterious effect on SHOX, first reported case of isolated SHOX enhancer duplication, and SHOX mutation (68.8%). In both ISS+ and LWD+ groups were positivity associated with a disproportionately short stature; in the ISS+ group, in combination with muscular hypertrophy. It seems that small PAR1 rearrangements might be quite frequent in the population. Our study suggests disproportionateness, especially in combination with muscular hypertrophy, as relevant indicators of ISS to be the effect of SHOX defect. Copyright © 2011 Elsevier B.V. All rights reserved.

Acid lake in N.Y. gets relief

Science.gov (United States)

A pond in the Adirondack Mountains of New York State has received a second soothing dose of baking soda. The 21 tons of sodium bicarbonate should moderate the pond's acidic conditions, lethal to fish and other forms of life.Wolf Pond, 25 miles (40 km) north of Saranac Lake, has developed an extremely low pH (4.5) because of acid rain and the runoff of acidic surface water, combined with very little outflow. The pond was first treated with sodium bicarbonate by t h e New York Department of Environmental Conservation in 1984; afterward the pH rose to about 6.2. Fish stocked by local residents have continued to live in the pond, despite the eventual rebound in its acidity.

Decadal Climate Change in Ny-Ålesund, Svalbard, A Representative Area of the Arctic

Directory of Open Access Journals (Sweden)

Minghu Ding

2018-04-01

Full Text Available In recent decades, global warming hiatus/slowdown has attracted considerable attention and has been strongly debated. Many studies suggested that the Arctic is undergoing rapid warming and significantly contributes to a continual global warming trend rather than a hiatus. In this study, we evaluated the climate changes of Ny-Ålesund, Svalbard, a representative location of the northern North Atlantic sector of the Arctic, based on observational records from 1975–2014. The results showed that the annual warming rate was four times higher than the global mean (+0.76 °C·decade−1 and was also much greater than Arctic average. Additionally, the warming trend of Ny-Ålesund started to slow down since 2005–2006, and our estimates showed that there is a 8–9 years-lagged, but significant, correlation between records of Ny-Ålesund and global HadCRUT4 datasets. This finding indicates that the Arctic was likely experiencing a hiatus pattern, which just appeared later than the low-mid latitudes due to transport processes of atmospheric circulations and ocean currents, heat storage effect of cryospheric components, multidecadal variability of Arctic cyclone activities, etc. This case study provides a new perspective on the global warming hiatus/slowdown debate.

Ready to Use Tissue Construct for Military Bone & Cartilage Trauma

Science.gov (United States)

2013-10-01

CONTRACTING ORGANIZATION : Columbia University in the City of New York New York, NY 10032 REPORT DATE: October 2013 TYPE OF REPORT: Annual... ORGANIZATION NAME(S) AND ADDRESS(ES) Trustees of Columbia University in the City of New York AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT...base plate for implantation was designed. Scaffolds were fabricated from a polycaprolactone hydroxyapatite polymer (PCL-HA) using a 3D bioprinter

Cultural competence springs up in the desert: the story of the center for cultural competence in health care at Weill Cornell Medical College in Qatar.

Science.gov (United States)

Elnashar, Maha; Abdelrahim, Huda; Fetters, Michael D

2012-06-01

The authors describe the factors that led Weill Cornell Medical College in Qatar (WCMC-Q) to establish the Center for Cultural Competence in Health Care from the ground up, and they explore challenges and successes in implementing cultural competence training.Qatar's capital, Doha, is an extremely high-density multicultural setting. When WCMC-Q's first class of medical students began their clinical clerkships at the affiliated teaching hospital Hamad Medical Corporation in 2006, the complicated nature of training in a multicultural and multilingual setting became apparent immediately. In response, initiatives to improve students' cultural competence were undertaken. Initiatives included launching a medical interpretation program in 2007; surveying the patients' spoken languages, examining the effect of an orientation program on interpretation requests, and surveying faculty using the Tool for Assessing Cultural Competence Training in 2008; implementing cultural competence training for students and securing research funding in 2009; and expanding awareness to the Qatar community in 2010. These types of initiatives, which are generally highly valued in U.S. and Canadian settings, are also apropos in the Arabian Gulf region.The authors report on their initial efforts, which can serve as a resource for other programs in the Arabian Gulf region.

Designing New York's Future

Science.gov (United States)

Giles, David

2012-01-01

The genius of Mayor Bloomberg's plan to develop a new applied sciences campus in New York City is that it acknowledges the increasingly pivotal role of academic institutions as drivers of local economic growth. At a time when large corporations may not be the reliable job producers they were in the past and cities like New York badly need to…

Analysis of GAGE, NY-ESO-1 and SP17 cancer/testis antigen expression in early stage non-small cell lung carcinoma

International Nuclear Information System (INIS)

Gjerstorff, Morten F; Pøhl, Mette; Olsen, Karen E; Ditzel, Henrik J

2013-01-01

The unique expression pattern and immunogenic properties of cancer/testis antigens make them ideal targets for immunotherapy of cancer. The MAGE-A3 cancer/testis antigen is frequently expressed in non-small cell lung cancer (NSCLC) and vaccination with MAGE-A3 in patients with MAGE-A3-positive NSCLC has shown promising results. However, little is known about the expression of other cancer/testis antigens in NSCLC. In the present study the expression of cancer/testis antigens GAGE, NY-ESO-1 and SP17 was investigated in patients with completely resected, early stage, primary NSCLC. Tumor biopsies from normal lung tissue and from a large cohort (n = 169) of NSCLC patients were examined for GAGE, NY-ESO-1 and SP17 protein expression by immunohistochemical analysis. The expression of these antigens was further matched to clinical and pathological features using univariate cox regression analysis. GAGE and NY-ESO-1 cancer/testis antigens were not expressed in normal lung tissue, while SP17 was expressed in ciliated lung epithelia. The frequency of GAGE, NY-ESO-1 and SP17 expression in NSCLC tumors were 26.0% (44/169), 11.8% (20/169) and 4.7% (8/169), respectively, and 33.1% (56/169) of the tumors expressed at least one of these antigens. In general, the expression of GAGE, NY-ESO-1 and SP17 was not significantly associated with a specific histotype (adenocarcinoma vs. squamous cell carcinoma), but high-level GAGE expression (>50%) was more frequent in squamous cell carcinoma (p = 0.02). Furthermore, the frequency of GAGE expression was demonstrated to be significantly higher in stage II-IIIa than stage I NSCLC (17.0% vs. 35.8%; p = 0.02). Analysis of the relation between tumor expression of GAGE and NY-ESO-1 and survival endpoints revealed no significant associations. Our study demonstrates that GAGE, NY-ESO-1 and SP17 cancer/testis antigens are candidate targets for immunotherapy of NSCLC and further suggest that multi-antigen vaccines may be beneficial

A mutation in the envelope protein fusion loop attenuates mouse neuroinvasiveness of the NY99 strain of West Nile virus

International Nuclear Information System (INIS)

Zhang Shuliu; Li Li; Woodson, Sara E.; Huang, Claire Y.-H.; Kinney, Richard M.; Barrett, Alan D.T.; Beasley, David W.C.

2006-01-01

Substitutions were engineered individually and in combinations at the fusion loop, receptor-binding domain and a stem-helix structure of the envelope protein of a West Nile virus strain, NY99, and their effects on mouse virulence and presentation of epitopes recognized by monoclonal antibodies (MAbs) were assessed. A single substitution within the fusion loop (L107F) attenuated mouse neuroinvasiveness of NY99. No substitutions attenuated NY99 neurovirulence. The L107F mutation also abolished binding of a non-neutralizing MAb, 3D9, whose epitope had not been previously identified. MAb 3D9 was subsequently shown to be broadly cross-reactive with other flaviviruses, consistent with binding near the highly conserved fusion loop

Retrofitting Garden-Style Apartments in Brooklyn, New York

Energy Technology Data Exchange (ETDEWEB)

Nolen, Heather [Steven Winter Associates, Inc., Norwalk, CT (United States); Maxwell, Sean [Steven Winter Associates, Inc., Norwalk, CT (United States); Neri, Robin [Steven Winter Associates, Inc., Norwalk, CT (United States); Grab, Joanna [Steven Winter Associates, Inc., Norwalk, CT (United States)

2016-02-01

This research effort sought to achieve a solution package that yields energy savings greater than 30% over the pre-existing conditions in a minimally intrusive multifamily retrofit project. The Consortium for Advanced Residential Buildings (CARB) partnered with L+M Development Partners, Inc. on a Mitchell-Lama Housing Program project, Marcus Garvey Village, in Brooklyn, NY (Climate Zone 4A). The Mitchell-Lama Housing Program is a form of housing subsidy in the state of New York that provides affordable rental and cooperative housing to moderate- and middle-income families. Marcus Garvey Village was founded in 1975 and contains 625 residential units (ranging from studios to 5-bedroom units) in thirty-two 4-story garden-style apartment structures built with concrete and faced in light brown brick. The single largest challenge for implementation of energy conservation measures at Marcus Garvey was working within occupied spaces. Measures are being implemented in phases to minimize disruption. As of August 2015, the retrofit work is over 50% complete. The wall insulation, sealing of the through wall AC vent, and installation of new oil-filled electric baseboards with advanced controls are conducted at one time, limiting disruption to the living room space. In a similar fashion, the kitchen work is done, then the bathroom. The final selection of energy conservation measures is projected to save 26.5% in source energy with a cost just under $3.7 million and utility bill savings of nearly $480,000 (of an average $1.8 million annual utility cost for the development).

77 FR 60901 - Safety Zone; Battle of Queenston Heights Bicentennial, Niagara River, Lewiston, NY

Science.gov (United States)

2012-10-05

..., Docket Operations, telephone 202-366-9826. SUPPLEMENTARY INFORMATION: Table of Acronyms DHS Department of... Lower Niagara River near the Silo Restaurant, Lewiston, NY. The Captain of the Port Buffalo has...

Orbital fractures: a review

Directory of Open Access Journals (Sweden)

Jeffrey M Joseph

2011-01-01

Full Text Available Jeffrey M Joseph, Ioannis P GlavasDivision of Ophthalmic Plastic and Reconstructive Surgery, Department of Ophthalmology, School of Medicine, New York University, New York, NY, USA; Manhattan Eye, Ear, and Throat Hospital, New York, NY, USAAbstract: This review of orbital fractures has three goals: 1 to understand the clinically relevant orbital anatomy with regard to periorbital trauma and orbital fractures, 2 to explain how to assess and examine a patient after periorbital trauma, and 3 to understand the medical and surgical management of orbital fractures. The article aims to summarize the evaluation and management of commonly encountered orbital fractures from the ophthalmologic perspective and to provide an overview for all practicing ophthalmologists and ophthalmologists in training.Keywords: orbit, trauma, fracture, orbital floor, medial wall, zygomatic, zygomatic complex, zmc fracture, zygomaticomaxillary complex fractures 

TU-E-TOUR-T-00: Exhibit Hall Guided Tours-Microdosimeters for Therapy (Tuesday)

International Nuclear Information System (INIS)

2016-01-01

Tour Leader: Indra Das, NYU Langone Medical Center, New York, NY Tour Guides: Hsui Ai, Indiana University School of Medicine, Indianapolis, IN Aaron Andersen, Indiana University School of Medicine, Indianapolis, IN Olga Volotoskova, NYU Langone Medical Center, New York, NY Participating Vendors: IBA PTW – New York RTI Electronics, Inc. Standard Imaging, Inc. Sun Nuclear Corporation Small fields are increasing used in specialized radiation treatments such as Gammaknife, Cyberknife, Tomotherapy, IMRT, VMAT, SRS and SBRT. Due to small field size electron transport creates lateral electronic disequilibrium and thus dosimetry could be very difficult. Microdetectors are used for small field dosimetry which will be discussed in preface of this tour as below: Understanding small field e.g. meaning and definition of small field IAEA definition and approach Characteristics of microdetectors in terms of perturbation, recombination, correction Suitability of microdetectors in small field dosimetry

76 FR 35937 - New York Disaster #NY-00105

Science.gov (United States)

2011-06-20

..., Hamilton, Herkimer, Lewis, Madison, Niagara, Oneida, Onondaga, Ontario, Steuben, Tioga, Ulster, Warren... Assistance Numbers 59002 and 59008) James E. Rivera, Associate Administrator for Disaster Assistance. [FR Doc...

78 FR 44187 - New York Disaster # NY-00136

Science.gov (United States)

2013-07-23

...; Herkimer; Madison; Montgomery; Niagara; Oneida; Otsego; Warren. The Interest Rates are: Percent For... for economic injury is 13668B (Catalog of Federal Domestic Assistance Numbers 59002 and 59008). James...

77 FR 67857 - New York Disaster # NY-00131

Science.gov (United States)

2012-11-14

.../2012. Physical Loan Application Deadline Date: 01/02/2013. Economic Injury (EIDL) Loan Application... that provide essential services of governmental nature may file disaster loan applications at the... Elsewhere For Economic Injury: Non-Profit Organizations Without Credit Available 3.000 Elsewhere The number...

Ny krigsførelse i informationsalderen? Om ‘Revolution in Military Affairs’ og Irakkrigen

Directory of Open Access Journals (Sweden)

Jens Claus Hansen

2005-09-01

Full Text Available Artiklen diskuterer, hvorvidt man efter Golfkrigen kan tale om en ‘Revolu- tion in Military Affairs’ – RMA – som nogle amerikanske krigsteoretikere hævder har fundet sted med anvendelsen af ny teknologi i moderne krigs- førelse. Forfatteren viser, hvordan moderne krigsstrategier har inkorpore- ret ny teknologi og mediebrug som bl.a. informationskrig, ‘Systems of Sys- tems’ og Network Centric Warfare. Forfatteren påpeger, at den strategiske anvendelse af informationsoperationer – herunder ‘embedded’ journalister – ikke har medført en demokratisering af nyhedsdækningen og heller ikke indebærer en øget sandhedsværdi. Afslutningsvis peger forfatteren på behovet for en ‘Revolution in Diplomatic Affairs’.

Prompt Gamma Activation Analysis of the Nyírlugos obsidian core depot find

Directory of Open Access Journals (Sweden)

Zsolt Kasztovszky

2014-03-01

Full Text Available The Nyírlugos obsidian core depot find is one of the most important lithic assemblages in the collection of the Hungarian National Museum (HNM. The original set comprised 12 giant obsidian cores, of which 11 are currently on the permanent archaeological exhibition of the HNM. One of the cores is known to be inDebrecen. The first publication attributed the hoard, on the strength of giant (flint blades known from the Early and Middle Copper Age Tiszapolgár and Bodrogkeresztúr cultures, to the Copper Age. In the light of recent finds it is more likely to belong to the Middle Neolithic period. The source area was defined as Tokaj Mts., about100 kmto the NW from Nyírlugos. The size and beauty of the exceptional pieces exclude any invasive analysis. Using Prompt Gamma Activation Analysis (PGAA, we can measure major chemical components and some key trace elements of stone artefacts with adequate accuracy to successfully determine provenance of obsidian. Recent methodological development also facilitated the study of relatively large objects like the Nyírlugos cores. The cores were individually measured by PGAA. The results show that the cores originate from the Carpathian 1 sources, most probably the Viničky variety (C1b. The study of the hoard as a batch is an important contribution to the assessment of prehistoric trade and allows us to reconsider the so-called Carpathian, especially Carpathian 1 (Slovakian sources.

Catherine Pouzoulet, New York, New York, Espace, Pouvoir, Citoyenneté dans une ville‑monde.

Directory of Open Access Journals (Sweden)

Frédérick Douzet

2006-03-01

Full Text Available Symbole de l’emprise économique des Etats‑Unis sur le monde, les tours jumelles du World Trade Center étaient aussi le symbole du statut de ville‑monde de la ville de New York et de l’insolente santé financière de son centre d’affaires à Manhattan. Rien de plus utile pour le comprendre que le livre de Catherine Pouzoulet, New York, New York, qui en décortiquant des décennies de politiques publiques, démontre avec talent comment la logique de marché a présidé à l’élaboration des priorités gest...

En ny vej at gå for udsatte unge i USA

DEFF Research Database (Denmark)

Petersen, Karen Bjerg; Andersen, Frans Ørsted

2018-01-01

kommet forslag om en ny ungdomsuddannelse, der skal kunne løse nogle af problemerne. Samtidig er der stigende mangel på arbejdskraft indenfor det teknisk-naturvidenskabelige-IT- og håndværks-mæssige område. Et område, som i USA ofte omtales som STEM, dvs. Science, Technology, Engineering, Math. I denne...

Depo-Provera (depot medroxyprogesterone acetate) use after bariatric surgery

OpenAIRE

Lam, Clarissa; Murthy, Amitasrigowri S

2016-01-01

Clarissa Lam,1 Amitasrigowri S Murthy2,3 1New York University School of Medicine, 2Department of Obstetrics and Gynecology, Bellevue Hospital Center, New York University School of Medicine, 3New York University Langone Medical Center, New York, NY, USA Abstract: In the US, obesity rates are increasing greatly. The Centers for Disease Control and Prevention estimates that 68.5% of Americans, including 63.9% of adult women older than 20 years, are overweight (body mas...

International Conference on the Physics of Electronic and Atomic Collisions (16th), Held in New York, NY on 26 July-1 August 1989. Third Conference Program

Science.gov (United States)

1989-08-01

Schlumborger- Doll Research SONY USA, Inc. UHVIns!ruments, Inc. United Techno’-’ies Research Center Xelon Instruments Sales. * Expresses appreciation for the...evening, 25 July: the Thursday evening reception at the New York Public Library: the Sunday cnainber music concert at NYU: and the Monday evening dinner...These fees entitle the, accompanying person to attend the conference dinner. receptions. and entertainment XVI ICPEAC LANGUAGE HOT TOPIC TALKS (11) The

Legionnaires' Disease Outbreaks and Cooling Towers, New York City, New York, USA.

Science.gov (United States)

Fitzhenry, Robert; Weiss, Don; Cimini, Dan; Balter, Sharon; Boyd, Christopher; Alleyne, Lisa; Stewart, Renee; McIntosh, Natasha; Econome, Andrea; Lin, Ying; Rubinstein, Inessa; Passaretti, Teresa; Kidney, Anna; Lapierre, Pascal; Kass, Daniel; Varma, Jay K

2017-11-01

The incidence of Legionnaires' disease in the United States has been increasing since 2000. Outbreaks and clusters are associated with decorative, recreational, domestic, and industrial water systems, with the largest outbreaks being caused by cooling towers. Since 2006, 6 community-associated Legionnaires' disease outbreaks have occurred in New York City, resulting in 213 cases and 18 deaths. Three outbreaks occurred in 2015, including the largest on record (138 cases). Three outbreaks were linked to cooling towers by molecular comparison of human and environmental Legionella isolates, and the sources for the other 3 outbreaks were undetermined. The evolution of investigation methods and lessons learned from these outbreaks prompted enactment of a new comprehensive law governing the operation and maintenance of New York City cooling towers. Ongoing surveillance and program evaluation will determine if enforcement of the new cooling tower law reduces Legionnaires' disease incidence in New York City.

Geohydrologic conditions at the Nuclear Fuel Reprocessing Plant and Waste-Management Facilities at the western New York Nuclear Service Center, Cattaraugus County, New York

International Nuclear Information System (INIS)

Bergeron, M.P.; Kappel, W.M.; Yager, R.M.

1987-01-01

A nuclear-fuel reprocessing plant, a high-level radioactive liquid-waste tank complex, and related waste facilities occupy 100 hectares (ha) within the Western New York Nuclear Service Center near West Valley, NY. The facilities are underlain by glacial and postglacial deposits that fill an ancestral bedrock valley. The main plant facilities are on an elevated plateau referred to as the north plateau. Groundwater on the north plateau moves laterally within a surficial sand and gravel from the main plant building to areas northeast, east, and southeast of the facilities. The sand and gravel ranges from 1 to 10 m thick and has a hydraulic conductivity ranging from 0.1 to 7.9 m/day. Two separate burial grounds, a 4-ha area for low-level radioactive waste disposal and a 2.9-ha area for disposal of higher-level waste are excavated into a clay-rich till that ranges from 22 to 28 m thick. Migration of an organic solvent from the area of higher level waste at shallow depth in the till suggests that a shallow, fractured, oxidized, and weathered till is a significant pathway for lateral movement of groundwater. Below this zone, groundwater moves vertically downward through the till to recharge a lacustrine silt and fine sand. Within the saturated parts of the lacustrine unit, groundwater moves laterally to the northeast toward Buttermilk Creek. Hydraulic conductivity of the till, based on field and laboratory analyses, ranges from 0.000018 to 0.000086 m/day

Comparison of SHOX and associated elements duplications distribution between patients (Lėri-Weill dyschondrosteosis/idiopathic short stature) and population sample.

Science.gov (United States)

Hirschfeldova, Katerina; Solc, Roman

2017-09-05

The effect of heterozygous duplications of SHOX and associated elements on Lėri-Weill dyschondrosteosis (LWD) and idiopathic short stature (ISS) development is less distinct when compared to reciprocal deletions. The aim of our study was to compare frequency and distribution of duplications within SHOX and associated elements between population sample and LWD (ISS) patients. A preliminary analysis conducted on Czech population sample of 250 individuals compared to our previously reported sample of 352 ISS/LWD Czech patients indicated that rather than the difference in frequency of duplications it is the difference in their distribution. Particularly, there was an increased frequency of duplications residing to the CNE-9 enhancer in our LWD/ISS sample. To see whether the obtained data are consistent across published studies we made a literature survey to get published cases with SHOX or associated elements duplication and formed the merged LWD, the merged ISS, and the merged population samples. Relative frequency of particular region duplication in each of those merged samples were calculated. There was a significant difference in the relative frequency of CNE-9 enhancer duplications (11 vs. 3) and complete SHOX (exon1-6b) duplications (4 vs. 24) (p-value 0.0139 and p-value 0.000014, respectively) between the merged LWD sample and the merged population sample. We thus propose that partial SHOX duplications and small duplications encompassing CNE-9 enhancer could be highly penetrant alleles associated with ISS and LWD development. Copyright © 2017 Elsevier B.V. All rights reserved.

Agil Stage-Gate®: ny model for udviklingsprojekter i mellemstore virksomheder

DEFF Research Database (Denmark)

Vedsmand, Tomas; Edwards, Kasper; Hvidt, Nicoline

Lær at udvikle nye produkter hurtigere og med større træfsikkerhed – ved at arbejde i sprint med agile metoder og træffe de rigtige beslutninger med Stage-Gate® Se også tilhørende: "Værktøjskasse til Agil Stage-Gate®: Ny model for udviklingsprojekter i mellemstore virksomheder" på http://dx.doi.org...

Dynamics of snow-air mercury exchange at Ny Ålesund during springtime 2011

Directory of Open Access Journals (Sweden)

Manca G.

2013-04-01

Full Text Available Continuous time series of flux measurements were carried out in Ny Ålesund, Spitsbergen, during a springtime field campaign from 31 of March to 3 of May, 2011. Flux measurements were integrated with mercury speciation analysis in order to understand the fate of mercury during atmospheric elemental gaseous mercury depletion events (AMDEs. Moreover a methodology for quality assurance of flux measurements is presented. Measurements were made at Gruvebadet, 1 km west from the Ny-Ålesund village (78˚55' N, 11˚56' E at an elevation of 18 m above sea level. Ambient concentrations of gaseous elemental mercury, divalent reactive gaseous mercury and particulate phase mercury were semicontinuously measured using an integrated Tekran system. Mercury depletion events were observed during the month of April and were characterized by an incomplete mercury destruction. Indeed Hg0 concentration was never below 0.49 ng m−3.

Urban and rural ambient air aldehyde levels in Schenectady, New York and on Whiteface Mountain, New York

Energy Technology Data Exchange (ETDEWEB)

Schulam, P; Newbold, R; Hull, L A

1985-01-01

The air in the city of Schenectady, NY was sampled daily and analyzed for the presence of low molecular weight aldehydes during the months of June-August 1983. The diurnal variation of the aldehyde concentrations was also determined over a two day period during August. The dominant aldehyde was formaldehyde and its concentration varied from about 1-31 ppb. There was also observed a significant daily variation that appeared to correlate with traffic conditions. The technique was also used to monitor the aldehyde levels on the summit of Whiteface Mountain in Wilmington, NY at the SUNYA Atmospheric Sciences Research Center. The monitoring was done on a daily basis during the week of 14-20 August and, during that week, every 3 h for a 3-day period. The two dominant aldehydes were formaldehyde and acetaldehyde and they varied in concentration from about 0.8-2.6 and 0.2-0.8 ppb, respectively.

33 CFR 334.85 - New York Harbor, adjacent to the Stapleton Naval Station, Staten Island, New York; restricted area.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false New York Harbor, adjacent to the Stapleton Naval Station, Staten Island, New York; restricted area. 334.85 Section 334.85 Navigation and... RESTRICTED AREA REGULATIONS § 334.85 New York Harbor, adjacent to the Stapleton Naval Station, Staten Island...

Suffrage in New York Counties.

Science.gov (United States)

Stein, Maren A.

1995-01-01

Maintains that the expansion of voting rights to African Americans and women is an appropriate topic for Social Studies courses. Discusses suffrage in New York state between 1848 and 1920. Includes a table depicting the women's suffrage campaign in New York state and a list of other resources on the topic. (CFR)

New York State's 1999 agritourism business study

Science.gov (United States)

Diane Kuehn; Duncan Hilchey

2002-01-01

Agritourism businesses (i.e., farm-based businesses that are open to visitors for recreational purposes) are becoming an important component of New York's tourism industry today. In order to estimate the economic impacts of these businesses on New York State and identify cost-effective management and marketing strategies for business owners, New York Sea Grant and...

Summary of selected health statistics for counties with nuclear facilities, New York State excluding New York City, 1960--1975

International Nuclear Information System (INIS)

Burometto, E.; Therriault, G.; Logrillo, V.

1977-08-01

A previous report of the Office of Biostatistics of the New York State Department of Health, issued in 1971, summarized selected health statistics for the period 1960 through 1969, comparing counties in Upstate New York (New York State exclusive of New York City) in which nuclear facilities are located with counties without such facilities. This report will present comparisons extending the analysis of the previous study through 1975. At various times during the period from 1960 to 1975 nuclear facilities were operating in 12 of the 57 Upstate counties. Westchester, Wayne and Oswego counties are the sites for the three commercial power plants operating in Upstate New York. A nuclear fuel reprocessing plant is located in Cattaraugus County. Facilities with testing, training or research reactors are located in eight other Upstate counties

New York: Les ecoles entre SURR et STAR (New York: Schools between SURR and STAR).

Science.gov (United States)

Ueberschlag, Roger

1994-01-01

Three problems of New York City (New York) schools--overpopulation, low academic standards, violence--are examined, and an effort led by parent and teacher organizations to improve conditions is described. Threatened closings (schools under registration review, SURR) and a program of violence reduction (Straight Talk about Risks, STAR) are noted.…

78 FR 50102 - Notice of Inventory Completion: Rochester Museum & Science Center, Rochester, NY

Science.gov (United States)

2013-08-16

.... 3003, of the completion of an inventory of associated funerary objects under the control of the....R50000] Notice of Inventory Completion: Rochester Museum & Science Center, Rochester, NY AGENCY: National... inventory of associated funerary objects, in consultation with the appropriate Indian tribes or Native...

New York: Multi-Speak City!

Science.gov (United States)

New York City Economic Development Council, NY.

This guide was written to help teachers make students aware of the multilingual and multi-ethnic nature of New York City in order to experience and explore different languages and customs. New York is a center for variety in language and culture in the areas of diplomacy, international commerce, media and communications, foods and fashion, the…

Bioenergy from willow. 1995 Annual report, November 1987--December 1995

Energy Technology Data Exchange (ETDEWEB)

White, E.H.; Abrahamson, L.P.

1997-07-01

Experiments were established at Tully, New York, by the State University of New York College of Environmental Science and Forestry, in cooperation with the University of Toronto and the Ontario Ministry of Natural Resources, to assess the potential of willows for wood biomass production. Specific objectives included determining the effects of clone type, fertilization, spacing, cutting cycle, and irrigation on biomass production. Production was high, with willow clone SV1 yielding nearly 32 oven dry tons per acre (odt ac{sup -1}) with three-year harvest cycle, irrigation, and fertilization. Clone type, fertilization, spacing, cutting cycle, and irrigation all significantly affected biomass production. Willow clone-site trials planted at Massena, and Tully, NY in 1993 grew well during 1994 and 1995, but some clones in the Massena trial were severely damaged by deer browse. Several new cooperators joined the project, broadening the funding base, and enabling establishment of additional willow plantings. Willow clone-site trials were planted at Himrod, King Ferry, Somerset, and Tully, NY, during 1995. A willow cutting orchard was planted during 1995 at the NYS Department of Environmental Conservation Saratoga Tree Nursery in Saratoga, NY. Plans are to begin site preparation for a 100+ acre willow bioenergy demonstration farm in central New York, and additional clone-site trials, in 1996.

78 FR 34582 - Safety Zone; Rochester Yacht Club Fireworks, Genesee River, Rochester, NY

Science.gov (United States)

2013-06-10

... 1625-AA00 Safety Zone; Rochester Yacht Club Fireworks, Genesee River, Rochester, NY AGENCY: Coast Guard... the Genesee River during the Rochester Yacht Club fireworks display. This temporary safety zone is... necessary to ensure the safety of spectators and vessels during the Rochester Yacht Club fireworks display...

Promoting knowledge of statins in patients with low health literacy using an audio booklet

Directory of Open Access Journals (Sweden)

Gossey JT

2011-08-01

Full Text Available J Travis Gossey1, Simon N Whitney2, Michael A Crouch3, Maria L Jibaja-Weiss2, Hong Zhang4, Robert J Volk41Department of Medicine, Weill Cornell Medical College, New York, NY, USA; 2Department of Family and Community Medicine, Baylor College of Medicine, Houston, TX, USA; 3Memorial Family Medicine Residency Program, Sugar Land, TX, USA; 4Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, and Houston Center for Education and Research on Therapeutics, Houston, TX, USABackground: Statins are generally well tolerated and effective at reducing a patient’s risk of both primary and secondary cardiovascular events. Many patients who would benefit from statin therapy either do not adhere to or stop taking their statin medication within the first year. We developed an audio booklet targeted to low health literacy patients to teach them about the benefits and risks of statins to help the patients adhere to their statin therapy.Methods: Through focus groups and an iterative design, an audio booklet was developed for both English-speaking and Spanish-speaking patients. We then compared the booklet with standard of care in 132 patients from our target patient population to measure its impact on knowledge and understanding of statins.Results: The patients enjoyed the audio booklet and showed significant increases in knowledge after listening to it when compared with those who received the standard of care materials.Conclusion: The audio booklet shows promise as a tool that can be used effectively in clinical practice to teach patients about statin therapy.Keywords: patient adherence, patient education, medical decision-making, hypercholesterolemia

Increasing Antibiotic Resistance in Shigella spp. from Infected New York City Residents, New York, USA.

Science.gov (United States)

Murray, Kenya; Reddy, Vasudha; Kornblum, John S; Waechter, HaeNa; Chicaiza, Ludwin F; Rubinstein, Inessa; Balter, Sharon; Greene, Sharon K; Braunstein, Sarah L; Rakeman, Jennifer L; Dentinger, Catherine M

2017-02-01

Approximately 20% of Shigella isolates tested in New York City, New York, USA, during 2013-2015 displayed decreased azithromycin susceptibility. Case-patients were older and more frequently male and HIV infected than those with azithromycin-susceptible Shigella infection; 90% identified as men who have sex with men. Clinical interpretation guidelines for azithromycin resistance and outcome studies are needed.

77 FR 43123 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2012-07-23

.... Fashion, Inc........ New York, NY May 28, 2011. The following certifications have been issued. The... Division and Mfg. Department, American Achievement Corporation. 81,594 Catalina Marketing St. Petersburg...

77 FR 14832 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2012-03-13

... workers from Kelly Services. 81,269 Cummins Filtration, A Cookeville, TN...... December 11, 2011...,302 American Technical Huntington Station, February 6, 2011. Ceramics New York Office, NY. AVX...

Modelling dune erosion, overwash and breaching at Fire Island (NY) during hurricane Sandy

NARCIS (Netherlands)

De Vet, P.L.M.; McCall, R.T.; Den Bieman, J.P.; Stive, M.J.F.; Van Ormondt, M.

2015-01-01

In 2012, Hurricane Sandy caused a breach at Fire Island (NY, USA), near Pelican Island. This paper aims at modelling dune erosion, overwash and breaching processes that occured during the hurricane event at this stretch of coast with the numerical model XBeach. By using the default settings, the

Comparison of sources of submicron particle number concentrations measured at two sites in Rochester, NY.

Science.gov (United States)

Kasumba, John; Hopke, Philip K; Chalupa, David C; Utell, Mark J

2009-09-01

Sources contributing to the submicron particles (100-470 nm) measured between January 2002 and December 2007 at two different New York State Department of Environmental Conservation (NYS DEC) sites in Rochester, NY were identified and apportioned using a bilinear receptor model, positive matrix factorization (PMF). Measurements of aerosol size distributions and number concentrations for particles in the size range of 10-500 nm have been made since December 2001 to date in Rochester. The measurements are being made using a scanning mobility particle sizer (SMPS) consisting of a DMA and a CPC (TSI models 3071 and 3010, respectively). From December 2001 to March 2004, particle measurements were made at the NYS DEC site in downtown Rochester, but it was moved to the eastside of Rochester in May 2004. Each measurement period was divided into three seasons i.e., winter (December, January, and February), summer (June, July, and August), and the transitional periods (March, April, May, September, October, and November) so as to avoid experimental uncertainty resulting from too large season-to-season variability in ambient temperature and solar photon intensity that would lead to unstable/non-stationary size distributions. Therefore, the seasons were analyzed independently for possible sources. Ten sources were identified at both sites and these include traffic, nucleation, residential/commercial heating, industrial emissions, secondary nitrate, ozone- rich secondary aerosol, secondary sulfate, regionally transported aerosol, and a mixed source of nucleation and traffic. These results show that the measured total outdoor particle number concentrations in Rochester generally vary with similar temporal patterns, suggesting that the central monitoring site data can be used to estimate outdoor exposure in other parts of the city.

Mosaic compound heterozygosity of SHOX resulting in Leri-Weill dyschondrosteosis with marked short stature: implications for disease mechanisms and recurrence risks.

Science.gov (United States)

Reish, Orit; Huber, Céline; Altarescu, Gheona; Chapman-Shimshoni, Daphne; Levy-Lahad, Ephrat; Renbaum, Paul; Mashevich, Maya; Munnich, Arnold; Cormier-Daire, Valérie

2010-09-01

Mutations or deletions in the SHOX gene cause Leri-Weill dyschondrosteosis (LWD) and Langer mesomelic dysplasia (LMD) when present in heterozygous or homozygous form, respectively. A new class of enhancer deletions was identified 30-250 kb downstream of SHOX. We identified a female patient with marked short stature, mosaic for monosomy X in 31% of her lymphocytes, and findings consistent with LWD. Additional molecular studies demonstrated segregation of 17 polymorphic markers flanking and including the SHOX locus, spanning 328 kb of pseudoautosomal region 1 (PAR1) region. A deletion up to 10 kb residing 197 kb downstream of SHOX gene was detected, which was germinally transmitted from her clinically unaffected father. This was associated with post-zygotic mosaic loss of the normal maternal X-chromosome, evidenced by fluorescent fragment analysis. Since most patients with LMD with deletions downstream of SHOX gene also have SHOX mutations in trans, it may suggest these deletions are associated with a milder phenotype. Further studies are required to elucidate the role of the former region in disease etiology. Mutations should be sought in clinically non-affected family members because of the variable expressivity in hemizygous carriers, and cytogenetic evaluation should be considered to detect possible X-chromosome rearrangements underlying the haploinsufficiency for the PAR1 when deletion is detected by molecular analysis. Similarly, when LWD and marked short stature occur in a patient with mosaic Turner syndrome, the possibility of mutations in SHOX and the downstream of SHOX gene should be considered. Copyright 2010 Wiley-Liss, Inc.

Devaney chaos, Li-Yorke chaos, and multi-dimensional Li-Yorke chaos for topological dynamics

Science.gov (United States)

Dai, Xiongping; Tang, Xinjia

2017-11-01

Let π : T × X → X, written T↷π X, be a topological semiflow/flow on a uniform space X with T a multiplicative topological semigroup/group not necessarily discrete. We then prove: If T↷π X is non-minimal topologically transitive with dense almost periodic points, then it is sensitive to initial conditions. As a result of this, Devaney chaos ⇒ Sensitivity to initial conditions, for this very general setting. Let R+↷π X be a C0-semiflow on a Polish space; then we show: If R+↷π X is topologically transitive with at least one periodic point p and there is a dense orbit with no nonempty interior, then it is multi-dimensional Li-Yorke chaotic; that is, there is a uncountable set Θ ⊆ X such that for any k ≥ 2 and any distinct points x1 , … ,xk ∈ Θ, one can find two time sequences sn → ∞ ,tn → ∞ with Moreover, let X be a non-singleton Polish space; then we prove: Any weakly-mixing C0-semiflow R+↷π X is densely multi-dimensional Li-Yorke chaotic. Any minimal weakly-mixing topological flow T↷π X with T abelian is densely multi-dimensional Li-Yorke chaotic. Any weakly-mixing topological flow T↷π X is densely Li-Yorke chaotic. We in addition construct a completely Li-Yorke chaotic minimal SL (2 , R)-acting flow on the compact metric space R ∪ { ∞ }. Our various chaotic dynamics are sensitive to the choices of the topology of the phase semigroup/group T.

EXTENDING THE UNITED STATES NUCLEAR DETERRENCE UMBRELLA TO THE MIDDLE EAST

Science.gov (United States)

2016-05-01

22 Robert D. Kaplan , Asia’s Cauldron: The South China Sea and the End of a Stable Pacific (New York: Random House, 2014), 166. 23 Office of the...25 Jean Lacouture, De Gaulle: The Ruler, 1945-1970, trans. Alan Sheridan (New York, NY: W. W. Norton and Company, 1992), 416. 26 Anderson and... Kaplan , Robert D. Asia’s Cauldron: The South China Sea and the End of a Stable Pacific. New York: Random House, 2014. Lacouture, Jean. De Gaulle

Bone Geometry as a Predictor of Tissue Fragility and Stress Fracture Risk

Science.gov (United States)

2004-10-01

eferences ........................................................................ 11 A ppendices ...School of Medicine, New York NY Stress fractures occur among persons with normal bones, no acute injury, and are most common among elite runners and

PENGARUH KOMPRES DINGIN TERHADAP PENURUNAN NYERI PERSALINAN KALA I FASE AKTIF DI BPS NY. MUJIYATI KABUPATEN LAMONGAN

Directory of Open Access Journals (Sweden)

Lilin Turlina

2016-03-01

Full Text Available The aim of research to determine the effect of cold pack on the decrese of pain childbirth at 1 active phase. The study design used Pre-Eksperiment Pratest-Postes Design. The population in this research where all women who give birth in BPS Ny.Mujiyati, Amd.Keb. Sample taken by simple random sampling. Data taken by observasion and analyzed using Wilcoxon Sign Rank Test significance 0,05. The result showed that cold pack was influence on the decrase of pain childbirth at 1 active phase in BPS Ny.Mujiyati, Amd.Keb. Joto Sanur village, Tikung SubDistrict, Lamongan District, year 2013.Keywords: cold pack, painful childbirth reduction

78 FR 31454 - Drawbridge Operation Regulation; Hudson River, Troy and Green Island, NY

Science.gov (United States)

2013-05-24

...-AA09 Drawbridge Operation Regulation; Hudson River, Troy and Green Island, NY AGENCY: Coast Guard, DHS... that governs the highway bridge (Troy Green Island) across the Hudson River, mile 152.7, between Troy... the regulations for the 112th Street Bridge, mile 155.4, between Troy and Cohoes which has been...

Designprocesser og arbejdsmiljø: Udvikling af ny teknologi til fødevareindustrien

DEFF Research Database (Denmark)

Broberg, Ole

1999-01-01

Dette papir handler om muligheder og betingelser for at inddrage arbejdsmiljøhensyn i designprocesser. Baggrunden for det er, at jeg har haft mulighed for at følge udviklingen af en ny maskine til fødevareindustrien næsten lige fra de grundlæggende idéer blev udviklet og foreløbig frem til i dag,...

76 FR 61269 - Protection of Stratospheric Ozone: acceptability Determination 26 for Significant New...

Science.gov (United States)

2011-10-04

.... Miller (eds.)). Cambridge University Press, Cambridge, United Kingdom and New York, NY, USA. This... Park Service, Water Resources Division, Fort Collins, Colorado. \\10\\ Material Safety Data Sheet for 3M...

The Business Improvement District Movement: Contributions to Public Administration and Management by Seth A. Grossman

Directory of Open Access Journals (Sweden)

Stephen Kleinschmit

2016-11-01

Full Text Available Grossman, S. (2016. The Business Improvement District Movement: Contributions to Public Administration and Management. New York, NY: Routledge. $49.95 (paperback, ISBN: 978-1-1386-6889-8.

The Air Force and Grand Strategy

Science.gov (United States)

2013-05-01

once needed 1,000 workers can now do the same work with 100.2 2 Barak H. Obama, President of the United...Press, 2001. Strassler, Robert. The Landmark Thucydides. Revised Ed. New York, NY: New York Free Press, 2008. Rosen , Stephen. Winning the Next...Force and Strategic Deterrence: 1951-1960. USAF Historical Division Liaison Office, 1967. Speeches Obama, Barak . President of the United

Report on ONR Conference on ’Dolphin Behavior and Cognition: Comparative and Ecological Aspects’, Hubbs-Sea World Research Institute, San Diego, California, 92109, July 6-9, 1983.

Science.gov (United States)

1983-11-01

Brookfield Zoo Brookfield, IL 60513 Robert Buhr Animal communication and cognition; Department of Linguistics neurolinguistics and neuropsychology Brown...Rockefeller University 1230 York Avenue New York, NY 10021 Henry Halff (observer) Personnel and Training Research Program .,,; Code 442 PT Arlington, VA 22212...observer) Physiology and Neurobiology Research Program Code 441 NP e., Office of Naval Research Arlington, VA 22217 Bernd Wursig Cetacean behavior

33 CFR 110.155 - Port of New York.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Port of New York. 110.155 Section... ANCHORAGE REGULATIONS Anchorage Grounds § 110.155 Port of New York. (a) Long Island Sound—(1) Anchorage No... northwest corner of the crib icebreaker north of the New York Central Railroad Company drawbridge across...

76 FR 71966 - TC Ravenswood, LLC v. New York Independent System Operator, Inc., New York State Reliability...

Science.gov (United States)

2011-11-21

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL12-9-000] TC Ravenswood... Procedures, 18 CFR 385.206, TC Ravenswood, LLC (Complainant) filed a complaint against the New York... York Public Service Commission. \\1\\ TC Ravenswood, LLC, 136 FERC ] 61,213 (2011). The Complainant...

76 FR 25706 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

Science.gov (United States)

2011-05-05

... complaint names as respondents Sony Corporation of Tokyo, Japan, Sony Corporation of America of New York, NY and Sony Electronics, Inc. of San Diego, CA. The complainant, proposed respondents, other interested...

76 FR 7583 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

Science.gov (United States)

2011-02-10

... digital televisions and components thereof. The complaint names as respondents Sony Corporation of Tokyo, Japan; Sony Corporation of America of New York, NY; Sony Electronics, Inc. of San Diego, CA. The...

75 FR 49555 - EPA's Denial of the Petitions To Reconsider the Endangerment and Cause or Contribute Findings for...

Science.gov (United States)

2010-08-13

... Change 2007. Cambridge University Press, Cambridge, United Kingdom and New York, NY, USA. As discussed in...-mail communications out of context and assert they are ``smoking gun'' evidence of wrongdoing and...

Download this PDF file

African Journals Online (AJOL)

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and Technology (KNUST) and how they are able to effectively manage them. To enable the stu- ... Keywords: Distance learners, relations, Feedback Systems, Time Management, Motivation ...... New York, NY: CBS College. Publishing.

Medline Plus

Full Text Available ... Knee Replacement Bi-Cruciate Stabilized (BCS) Total Knee System (Hospital for Special Surgery, New York, NY, 12/11/2013) Computer Guided Knee Replacement (Broward Health North Medical Center, ...

New York State Technical & Economic MAGLEV Evaluation

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1991-06-01

The New York State Energy Research and Development Authority, with the : assistance of the Departments of Transportation, Economic Development, Environmental Conservation, and the New York State Thruway Authority, is undertaking a comprehensive, syst...

New York Racing Association (NYRA) Clean Water Act Settlement

Science.gov (United States)

The New York Racing Association (NYRA) is a not-for-profit corporation that operates the Aqueduct Racetrack in Ozone Park, New York, pursuant to a franchise agreement with the State of New York, who owns the facility.

Morte e ironia em “A exposição das rosas”, de István Örkény

Directory of Open Access Journals (Sweden)

Leonardo Francisco Soares

2009-03-01

Full Text Available Estudo da narrativa “A exposição das rosas”, de István Örkény, examinando o tema da morte e a problematização de sua representação. Nascido em 1912 e falecido em 1979, Örkény testemunhou de forma intensa e intrínseca as grandes convulsões que abalaram a Europa no século 20. Longe do panfleto, sua literatura tem como traço marcante a ironia. Na novela analisada, Iron Korom, um jovem e inexperiente diretor, tenta realizar um documentário sobre as horas finais de três pacientes desenganados, com o intuito de, nas suas palavras, ajudar os seus contemporâneos a compreenderem a experiência da morte. A partir do projeto de Korom, o texto de Örkény coloca-­nos diante de um confim: o limite da representação.

Large Scale System Defense

Science.gov (United States)

2008-10-01

NUMBER 00 5f. WORK UNIT NUMBER 01 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Columbia University 1700 Broadway New York NY 10019-5905 8...PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) AFRL/RIGA 525 Brooks Rd. Rome NY 13441-4505...pealing because of the need to modify source code. Since source-level annotations serve as a vestigial policy, we articulated a way to augment self

Babesiosis in Lower Hudson Valley, New York

Centers for Disease Control (CDC) Podcasts

This podcast discusses a study about an increase in babesiosis in the Lower Hudson Valley of New York state. Dr. Julie Joseph, Assistant Professor of Medicine at New York Medical College, shares details of this study.

77 FR 52058 - Notice of Inventory Completion: Longyear Museum of Anthropology, Colgate University, Hamilton, NY

Science.gov (United States)

2012-08-28

... Inventory Completion: Longyear Museum of Anthropology, Colgate University, Hamilton, NY AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Longyear Museum of Anthropology has completed an... cultural affiliation with the human remains should contact the Longyear Museum of Anthropology at the...

PAR1 deletions downstream of SHOX are the most frequent defect in a Spanish cohort of Léri-Weill dyschondrosteosis (LWD) probands.

Science.gov (United States)

Benito-Sanz, Sara; del Blanco, Darya Gorbenko; Aza-Carmona, Miriam; Magano, Luis F; Lapunzina, Pablo; Argente, Jesús; Campos-Barros, Angel; Heath, Karen E

2006-10-01

Léri-Weill dyschondrosteosis (LWD) is a skeletal dysplasia characterized by disproportionate short stature and Madelung deformity. Mutations or deletions of the SHOX gene have been previously identified as the main cause of LWD. We recently identified the existence of a second class of pseudoautosomal region 1 (PAR1) deletions which do not include SHOX, implicated in the etiopathogenesis of LWD. The deletions map at least 30-250 kb downstream of SHOX, are variable in size and clearly cosegregate with the LWD phenotype. In order to determine the frequency of this new type of deletions in the Spanish population we analyzed the distribution of PAR1 defects, including the screening of SHOX deletions, mutations, and PAR1 deletions downstream of SHOX, in a total of 26 LWD probands by a combination of MLPA, microsatellite analysis, SNP genotyping, dHPLC, and DNA sequencing. A molecular defect was identified in 16/26 LWD patients (61.5%): 10 PAR1 deletions downstream of SHOX, four SHOX encompassing deletions, and two SHOX mutations. No apparent phenotypic differences were observed between patients with SHOX defects and those with PAR1 deletions downstream of SHOX. In the examined cohort of Spanish LWD probands, PAR1 deletions downstream of SHOX represent the highest proportion of identified mutations (38%) compared to SHOX deletions (15%) and mutations (8%). As a consequence of our findings, the screening of this region should be included in the routine genetic testing of LWD. Also, LWD patients who tested negative for SHOX defects should be re-evaluated for PAR1 deletions downstream of SHOX.

Use of restraints

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... to Advanced Skills . 9th ed. New York, NY: Pearson; 2017:chap 7. The Joint Commission website. The Comprehensive Accreditation Manual for Hospitals: Human Resources. www.jointcommission.org . Updated January 1, 2015. ...

75 FR 5967 - Procurement List; Additions and Deletions

Science.gov (United States)

2010-02-05

... 651-F WEST 14TH STREET, PANAMA CITY, FL NPA (Subcontractor): Wiregrass Rehabilitation Center, Inc... Contracting Activity: GSA/FSS OFC SUP CTR--PAPER PRODUCTS, NEW YORK, NY Services Service Type/Location: Food...

78 FR 65617 - Procurement List; Additions

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2013-11-01

..., 9th Floor, De Diego Ave. Parada 22, Santurce, PR NPA: The Corporate Source, Inc., New York, NY... Communication & Electrical Room, 500 Airport Blvd., 115, Lake Charles, LA. NPA: Calcasieu Association for...

Lymphocytosis (High Lymphocyte Count)

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... com/test-catalog/Clinical+and+Interpretive/9109. Accessed May 19, 2016. Kaushansky K, et al. Lymphocytosis and lymphocytopenia. In: Williams Hematology. 9th ed. New York, N.Y.: The McGraw-Hill ...

77 FR 43167 - Safety Zone; Electric Zoo Fireworks, East River, Randall's Island, NY

Science.gov (United States)

2012-07-24

... establishes a temporary safety zone on the waters of the East River in the vicinity of Randall's Island, NY.... This temporary safety zone will restrict vessels from a portion of the East River around the location... area is a temporary safety zone: all navigable waters of the East River within a 164-yard radius of the...

Publication List - New York State Museum.

Science.gov (United States)

New York State Museum, Albany.

Presented is a list of publications in six areas: (1) Anthropology and Archeology, (2) Botany, (3) Entomology, (4) Zoology, (5) Geology and Paleontology, and (6) Miscellaneous. This list was produced by the New York State Department of Education in cooperation with the New York State Museum. The list includes the publication number, author(s),…

77 FR 42642 - Safety Zone; City of Ogdensburg Fireworks, St. Lawrence River, Ogdensburg, NY

Science.gov (United States)

2012-07-20

...-AA00 Safety Zone; City of Ogdensburg Fireworks, St. Lawrence River, Ogdensburg, NY AGENCY: Coast Guard... portion of the St. Lawrence River during the City of Ogdensburg Fireworks display. This temporary safety... as follows: Sec. 165.T09-0608 Safety Zone; City of Ogdensburg Fireworks, St. Lawrence River...

Energy literacy of secondary students in New York State (USA): A measure of knowledge, affect, and behavior

International Nuclear Information System (INIS)

DeWaters, Jan E.; Powers, Susan E.

2011-01-01

Energy literacy, which encompasses broad content knowledge as well as affective and behavioral characteristics, will empower people to make appropriate energy-related choices and embrace changes in the way we harness and consume energy. Energy literacy was measured with a written questionnaire completed by 3708 secondary students in New York State, USA. Results indicate that students are concerned about energy problems (affective subscale mean 73% of the maximum attainable score), yet relatively low cognitive (42% correct) and behavioral (65% of the maximum) scores suggest that students may lack the knowledge and skills they need to effectively contribute toward solutions. High school (HS) students scored significantly better than middle school (MS) students on the cognitive subscale; gains were greatest on topics included in NY State educational standards, and less on topics related to 'practical' energy knowledge such as ways to save energy. Despite knowledge gains, there was a significant drop in energy conservation behavior between the MS and HS students. Intercorrelations between groups of questions indicate energy-related behaviors are more strongly related to affect than to knowledge. These findings underscore the need for education that improves energy literacy by impacting student attitudes, values and behaviors, as well as broad content knowledge. - Research highlights: → Energy literacy of secondary students in New York State, US, was measured with a written survey. → Students scored 42%, 65%, and 73% (out of 100%) on cognitive, affective, and behavioral subscales. → HS students scored higher on cognitive, but lower on behavioral questions than MS students. → Results suggest energy-related behaviors more closely related to affective factors than to knowledge. → Study underscores importance of influencing attitudes/values to realize energy-related behavioral change.

Energy literacy of secondary students in New York State (USA): A measure of knowledge, affect, and behavior

Energy Technology Data Exchange (ETDEWEB)

DeWaters, Jan E., E-mail: dewaters@clarkson.ed [Clarkson University, Institute for a Sustainable Environment, Potsdam, NY 13699-5710 (United States); Powers, Susan E. [Clarkson University, Institute for a Sustainable Environment, Potsdam, NY 13699-5710 (United States)

2011-03-15

Energy literacy, which encompasses broad content knowledge as well as affective and behavioral characteristics, will empower people to make appropriate energy-related choices and embrace changes in the way we harness and consume energy. Energy literacy was measured with a written questionnaire completed by 3708 secondary students in New York State, USA. Results indicate that students are concerned about energy problems (affective subscale mean 73% of the maximum attainable score), yet relatively low cognitive (42% correct) and behavioral (65% of the maximum) scores suggest that students may lack the knowledge and skills they need to effectively contribute toward solutions. High school (HS) students scored significantly better than middle school (MS) students on the cognitive subscale; gains were greatest on topics included in NY State educational standards, and less on topics related to 'practical' energy knowledge such as ways to save energy. Despite knowledge gains, there was a significant drop in energy conservation behavior between the MS and HS students. Intercorrelations between groups of questions indicate energy-related behaviors are more strongly related to affect than to knowledge. These findings underscore the need for education that improves energy literacy by impacting student attitudes, values and behaviors, as well as broad content knowledge. - Research highlights: {yields} Energy literacy of secondary students in New York State, US, was measured with a written survey. {yields} Students scored 42%, 65%, and 73% (out of 100%) on cognitive, affective, and behavioral subscales. {yields} HS students scored higher on cognitive, but lower on behavioral questions than MS students. {yields} Results suggest energy-related behaviors more closely related to affective factors than to knowledge. {yields} Study underscores importance of influencing attitudes/values to realize energy-related behavioral change.

Data and Statistics on New York's Mining Resources - NYS Dept. of

Science.gov (United States)

): Search DEC D E C banner Home » Lands and Waters » Mining & Reclamation » Data and Statistics on New York's Mining Resources Skip to main navigation Data and Statistics on New York's Mining Resources Statistics on New York's Mining Resources: Mines in New York - Information on active mines in New York State

77 FR 71666 - New York Disaster Number NY-00131

Science.gov (United States)

2012-12-03

... (FEMA-4085-DR), dated 11/03/2012. Incident: Hurricane Sandy. Incident Period: 10/27/2012 through 11/08... 76155. FOR FURTHER INFORMATION CONTACT: A. Escobar, Office of Disaster Assistance, U.S. Small Business Administration, 409 3rd Street SW., Suite 6050, Washington, DC 20416. SUPPLEMENTARY INFORMATION: The notice of...

76 FR 68803 - New York Disaster Number NY-00108

Science.gov (United States)

2011-11-07

.../ 2011. Incident: Hurricane Irene. Incident Period: 08/26/2011 through 09/05/2011. DATES: Effective Date..., Processing and Disbursement Center, 14925 Kingsport Road, Fort Worth, TX 76155. FOR FURTHER INFORMATION...., Suite 6050, Washington, DC 20416. SUPPLEMENTARY INFORMATION: The notice of the President's major...

78 FR 20370 - New York Disaster Number NY-00130

Science.gov (United States)

2013-04-04

.../ 2012. Incident: Hurricane Sandy. Incident Period: 10/27/2012 through 11/08/2012. Effective Date: 03/28... and Disbursement Center, 14925 Kingsport Road, Fort Worth, TX 76155. FOR FURTHER INFORMATION CONTACT...., Suite 6050, Washington, DC 20416. SUPPLEMENTARY INFORMATION: The Notice Of The President's Major...

76 FR 58329 - New York Disaster Number NY-00108

Science.gov (United States)

2011-09-20

.../ 2011. Incident: Hurricane Irene. Incident Period: 08/26/2011 through 09/05/2011. Effective Date: 09/08... and Disbursement Center, 14925 Kingsport Road, Fort Worth, TX 76155. FOR FURTHER INFORMATION CONTACT...., Suite 6050, Washington, DC 20416. SUPPLEMENTARY INFORMATION: The notice of the Presidential disaster...

76 FR 58328 - New York Disaster Number NY-00108

Science.gov (United States)

2011-09-20

.../ 2011. Incident: Hurricane Irene. Incident Period: 08/26/2011 through 09/05/2011. Effective Date: 09/10... and Disbursement Center, 14925 Kingsport Road, Fort Worth, TX 76155. FOR FURTHER INFORMATION CONTACT...., Suite 6050, Washington, DC 20416. SUPPLEMENTARY INFORMATION: The notice of the Presidential disaster...

78 FR 7848 - New York Disaster Number NY-00130

Science.gov (United States)

2013-02-04

.../ 2012. Incident: Hurricane Sandy. Incident Period: 10/27/2012 through 11/08/2012. Effective Date: 01/25... and Disbursement Center, 14925 Kingsport Road, Fort Worth, TX 76155. FOR FURTHER INFORMATION CONTACT...., Suite 6050, Washington, DC 20416. SUPPLEMENTARY INFORMATION: The notice of the President's major...

78 FR 15109 - New York Disaster Number NY-00130

Science.gov (United States)

2013-03-08

.../ 2012. Incident: Hurricane Sandy. Incident Period: 10/27/2012 through 11/08/2012. Effective Date: 02/27... INFORMATION CONTACT: A. Escobar, Office of Disaster Assistance, U.S. Small Business Administration, 409 3rd Street SW., Suite 6050, Washington, DC 20416. SUPPLEMENTARY INFORMATION: The notice of the President's...

77 FR 71666 - New York Disaster Number NY-00130

Science.gov (United States)

2012-12-03

.../ 2012. Incident: Hurricane Sandy. Incident Period: 10/27/2012 through 11/08/2012. Effective Date: 11/19... and Disbursement Center, 14925 Kingsport Road, Fort Worth, TX 76155. FOR FURTHER INFORMATION CONTACT...., Suite 6050, Washington, DC 20416 SUPPLEMENTARY INFORMATION: The notice of the President's major disaster...

77 FR 74907 - New York Disaster Number NY-00130

Science.gov (United States)

2012-12-18

.../ 2012. Incident: Hurricane Sandy. Incident Period: 10/27/2012 through 11/08/2012. Effective Date: 12/10... and Disbursement Center, 14925 Kingsport Road, Fort Worth, TX 76155. FOR FURTHER INFORMATION CONTACT...., Suite 6050, Washington, DC 20416. SUPPLEMENTARY INFORMATION: The notice of the President's major...

EnviroAtlas - New York, NY - Near Road Tree Buffer

Data.gov (United States)

U.S. Environmental Protection Agency — This EnviroAtlas dataset addresses the tree buffer along heavily traveled roads. The roads are interstates, arterials, and collectors within the EnviroAtlas...

EnviroAtlas - New York, NY - Green Space Proximity Gradient

Data.gov (United States)

U.S. Environmental Protection Agency — In any given 1-square meter point in this EnviroAtlas dataset, the value shown gives the percentage of square meters of greenspace within 1/4 square kilometer...

EnviroAtlas - New York, NY - Demographics by Block Group

Data.gov (United States)

U.S. Environmental Protection Agency — This EnviroAtlas dataset is a summary of key demographic groups for the EnviroAtlas community. This dataset was produced by the US EPA to support research and online...

30 CFR 57.5037 - Radon daughter exposure monitoring.

Science.gov (United States)

2010-07-01

... Floor, New York, NY 10036; http://www.ansi.org. The mine operator may request that the required exhaust..., haulageways, shops, stations, lunch rooms, magazines, and any other place or location where persons work...

76 FR 7582 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

Science.gov (United States)

2011-02-10

... names as respondents Sony Corporation of Tokyo, Japan; Sony Corporation of America of New York, NY; Sony Electronics, Inc. of San Diego, CA; Sony Computer Entertainment, Inc. of Tokyo, Japan; and Sony Computer...

76 FR 80448 - VASRD Forum-Improving VA's Disability Evaluation Criteria for Neurological Conditions and...

Science.gov (United States)

2011-12-23

... Office located at 245 West Houston Street, New York, NY 10014. Public Comment: Contingent upon available capacity and time, individuals wishing to make oral statements or ask questions will be accommodated on a...

The inherent purpose of ontology in ecology: The immutable use of Hans Jonas’s works

Directory of Open Access Journals (Sweden)

Raluca Deleanu

2014-12-01

Full Text Available Theresa Morris, Hans Jonas’s Ethic of Responsibility: From Ontology to Ecology, Albany, NY: State University of New York Press, SUNY Series in Environmental Philosophy and Ethics, 2013, 236 p.

77 FR 45656 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Pistoia Alliance...

Science.gov (United States)

2012-08-01

..., PORTUGAL; Deloitte Consulting LLP, New York, NY; Mary Chitty (individual member), Needham, MA; and Hewlett- Packard Company, Palo Alto, CA, have been added as parties to this venture. No other changes have been...

77 FR 39638 - Safety Zone; Barbara Harder Wedding Fireworks, Lake Erie, Lake View, NY

Science.gov (United States)

2012-07-05

... environmental risk to health or risk to safety that may disproportionately affect children. 10. Indian Tribal... be held on Lake Erie near Lake View, NY. The Captain of the Port Buffalo has determined that fireworks launched proximate to a gathering of watercraft pose a significant risk to public safety and...

Mission Command During The Falklands War: Opportunities And Limitations

Science.gov (United States)

2016-05-26

Military Studies Henry A. Arnold III, COL Accepted this 10th day of May 2016 by: _____________________________________, Director, Graduate Degree Programs...Max Hastings and Simon Jenkins , The Battle for the Falklands (New York, NY: W. W. Norton & Company, 1984), 65. 8...Falklands: The Battalion at War. London: Buchan & Enright, 1983. Hastings, Max, and Simon Jenkins . The Battle for the Falklands. New York: W. W. Norton

78 FR 44917 - Anchorage Regulations; Port of New York

Science.gov (United States)

2013-07-25

...-AA01 Anchorage Regulations; Port of New York AGENCY: Coast Guard, DHS. ACTION: Notice of proposed... New York. This action is necessary to facilitate safe navigation and provide safe and secure... this rule, call or email Mr. Jeff Yunker, Sector New York, Waterways Management Division, U.S. Coast...

75 FR 22323 - Anchorage Regulations; Port of New York

Science.gov (United States)

2010-04-28

...-AA01 Anchorage Regulations; Port of New York AGENCY: Coast Guard, DHS. ACTION: Supplemental notice of..., Coast Guard Sector New York, Waterways Management Division; telephone 718-354-4195, e-mail Jeff.M.Yunker... Purpose The Hudson River Pilots Association, through the Port of New York/ New Jersey Harbor Safety...

Definition and Facts for Constipation

Science.gov (United States)

... Causes Diagnosis Treatment Eating, Diet, & Nutrition Clinical Trials Definition & Facts for Constipation What is constipation? Constipation is ... and Treatment. New York, NY: Springer Science and Business Media; 2014. May 2018 Share Previous: Constipation Next: ...

American Geriatrics Society

Science.gov (United States)

... Learn More Social Media Facebook Twitter LinkedIn Instagram Social Media Bar Right Menu Annual Meeting Donate to our Foundation Contact Us American Geriatrics Society 40 Fulton St., 18th Floor New York, NY ...

Prescott’s Microbiology, Eighth Edition

OpenAIRE

Dobbins, Joanne J.

2010-01-01

Review of: Prescott’s Microbiology, Eighth Edition. Joanne M. Willey, Linda M. Sherwood, and Christopher J. Woolverton. 2011. McGraw-Hill Higher Education, NewYork, NY. 1070 pages. ISBN- 978-0-07-337526-7.

Multi-objective optimisation with stochastic discrete-event simulation ...

African Journals Online (AJOL)

at costs negotiated between the banking group and a CIT company. The cost structure ... Costs associated with covering the distances between these ATMs ...... [5] Daganzo CF, 2005, Logistics systems analysis, Springer, New York (NY).

76 FR 11512 - In the Matter of Certain Liquid Crystal Display Devices, Products Containing Same, and Methods...

Science.gov (United States)

2011-03-02

..., Taipei 114, Taiwan. Haier America Trading LLC, 1356 Broadway, New York, NY 10018. Haier Group Company, 1 Haier Road, Hi-Tech Zone, Qingdao 266101, China. LG Electronics Inc., LG Twin Towers 20, Yoido-dong...

76 FR 48178 - Notice of Inventory Completion: Longyear Museum of Anthropology, Colgate University, Hamilton, NY

Science.gov (United States)

2011-08-08

...: Longyear Museum of Anthropology, Colgate University, Hamilton, NY AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Longyear Museum of Anthropology has completed an inventory of a human remain... human remain should contact the Longyear Museum of Anthropology at the address below by September 7...

New York City's Children First: Lessons in School Reform

Science.gov (United States)

Kelleher, Maureen

2014-01-01

Under Mayor Michael Bloomberg, New York City's education system embarked on a massive change effort, known as Children First, that produced significant results: new and better school options for families, more college-ready graduates, and renewed public confidence in New York City's schools. New York City's reform effort has also produced…

76 FR 20524 - Anchorage Regulations; Port of New York

Science.gov (United States)

2011-04-13

...-AA01 Anchorage Regulations; Port of New York AGENCY: Coast Guard, DHS. ACTION: Final rule. SUMMARY: The... Yunker, Coast Guard Sector New York, Waterways Management Division; telephone 718-354-4195, e-mail Jeff.M... New York in the Federal Register (74 FR 47906). We received one comment on the NPRM. No public meeting...

High temperature dielectric properties of (BxNyOz thin films deposited using ion source assisted physical vapor deposition

Directory of Open Access Journals (Sweden)

N. Badi

2015-12-01

Full Text Available The dielectric integrity has been one of the major obstacle in bringing out capacitor devices with suitable performance characteristics at high temperatures. In this paper, BxNyOz dielectric films for high temperature capacitors solutions are investigated. The films were grown on silicon substrate by using ion source assisted physical vapor deposition technique. The as-grown films were characterized by SEM, XRD, and XPS. The capacitor structures were fabricated using BxNyOz as a dielectric and titanium as metal electrodes. The elaborated devices were subjected to electrical and thermal characterization. They exhibited low electrical loss and very good stability when subjected to high temperature for a prolonged period of time.

77 FR 52737 - Ocean Transportation Intermediary License Revocations

Science.gov (United States)

2012-08-30

..., Inc. Address: 462 7th Avenue, 14th Floor, New York, NY 10018. Date Revoked: July 21, 2012. Reason... Logistics. Address: 380 Magazine Avenue, Savannah, GA 31415. Date Revoked: August 9, 2012. Reason: Failed to...

29 CFR 1910.95 - Occupational noise exposure.

Science.gov (United States)

2010-07-01

... equipment rather than to purchase it. Names of equipment suppliers may be found in the telephone book... Institute of Physics, 333 E. 45th St., New York, NY 10017; American National Standards Institute, Inc., 1430...

Emergency Meal Planning for Diabetics

Science.gov (United States)

... emergency . What should I expect during an emergency situation? Many things we depend on daily may not ... 2017 National Kidney Foundation, Inc., 30 East 33rd Street, New York, NY 10016, 1-800-622-9010. ...

78 FR 75911 - Procurement List; Proposed Additions and Deletions

Science.gov (United States)

2013-12-13

... persons who are blind or have other severe disabilities and to delete products and a service previously...: General Services Administration, New York, NY NSN: 8955-01-E61-3689--Coffee, Roasted, Ground, 39 oz. bag...

77 FR 24554 - Culturally Significant Objects Imported for Exhibition; Determinations: “Quay Brothers: On...

Science.gov (United States)

2012-04-24

... display of the exhibit objects at The Museum of Modern Art, New York, NY, from on or about August 12, 2012... temporary exhibition within the United States, are of cultural significance. The objects are imported...

46 CFR 154.1 - Incorporation by reference.

Science.gov (United States)

2010-10-01

... 42nd Street, New York, NY 10036 ANSI Z89.1-69 Safety Requirements for Industrial Head Protection, 1969... Equipment of Ships Carrying Liquefied Gases in Bulk, 1976 Code For Existing Ships Carrying Liquefied Gases...

New York's response to the national LLRW disposal legislation

International Nuclear Information System (INIS)

Orazio, A.F.; Schwarz, W.F.; Feeney, A.X.

1988-01-01

The Federal Low Level Radioactive Waste Policy Act (LLRWPA) and its amendments brought about a shift from commercial responsibility to state responsibility for low level radioactive waste (LLRW) disposal. This shift required New York to evaluate various policy options for handling its new LLRW disposal responsibility. After passage of the 1980 Federal Act, New York participated in efforts which resulted in a proposed interstate compact in the Northeast. Following a review of the proposed compact, as well as other options, New York decided to assume by itself full responsibility for disposing of its LLRW. In July 1986, New York enacted the New York State LLRW Management Act. This act provides New York with a detailed plan for establishing a LLWR disposal facility by the 1993 federal deadline. This paper consists of two segments. The first describes the major provisions of the State Act assigning responsibilities to the various agencies involved and reports on their progress. The second segment discusses the current activities of those involved in implementing the State Act with an emphasis on the recent and future activities of the Siting Commission

77 FR 46349 - Safety Zone; DeStefano Wedding Fireworks Display, Patchogue Bay, Patchogue, NY

Science.gov (United States)

2012-08-03

... announced by a later notice in the Federal Register. B. Regulatory History and Information This is a first time event with no regulatory history. C. Basis and Purpose The legal basis for this temporary rule is... Bay'' restaurant in Patchogue, NY. This rule will be effective from 8:30 p.m. on November 3, 2012...

76 FR 31679 - Saratoga and North Creek Railway, LLC-Operation Exemption-Warren County, NY

Science.gov (United States)

2011-06-01

... that it is negotiating the terms of an agreement with the County to restore common carrier rail freight... operate approximately 39.07 miles of rail line owned by Warren County, NY (the County), a noncarrier... Class III rail carrier and a subsidiary of Permian Basin Railways, Inc., which in turn is owned by Iowa...

75 FR 15739 - International Business Machines Corporation: Armonk, NY; Notice of Termination of Investigation

Science.gov (United States)

2010-03-30

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-70,580] International Business Machines Corporation: Armonk, NY; Notice of Termination of Investigation Pursuant to Section 223 of the Trade Act of 1974, as amended, an investigation was initiated in response to a petition filed on May 21, 2009 on behalf of workers of International...

Building America Case Study: Retrofitting Garden-Style Apartments, Brooklyn, New York

Energy Technology Data Exchange (ETDEWEB)

H. Nolen, S. Maxwell, R. Neri, J. Grab

2016-12-01

This research effort sought to achieve a solution package that yields energy savings greater than 30 percent over the pre-existing conditions in a minimally intrusive multifamily retrofit project. The Consortium for Advanced Residential Buildings (CARB) partnered with L+M Development Partners, Inc. on a Mitchell-Lama Housing Program project, Marcus Garvey Village, in Brooklyn, NY (Climate Zone 4A). The Mitchell-Lama Housing Program is a form of housing subsidy in the state of New York that provides affordable rental and cooperative housing to moderate- and middle-income families. Marcus Garvey Village was founded in 1975 and contains 625 residential units (ranging from studios to 5-bedroom units) in thirty-two 4-story garden-style apartment structures built with concrete and faced in light brown brick. The single largest challenge for implementation of energy conservation measures at Marcus Garvey was working within occupied spaces. Measures are being implemented in phases to minimize disruption. As of August 2015, the retrofit work is over 50 percent complete. The wall insulation, sealing of the through wall AC vent, and installation of new oil-filled electric baseboards with advanced controls are conducted at one time, limiting disruption to the living room space. In a similar fashion, the kitchen work is done, then the bathroom. The final selection of energy conservation measures is projected to save 26.5 percent in source energy with a cost just under $3.7 million and utility bill savings of nearly $480,000 (of an average $1.8 million annual utility cost for the development).

Major depressive disorder: mechanism-based prescribing for personalized medicine

Directory of Open Access Journals (Sweden)

Saltiel PF

2015-03-01

Full Text Available Philip F Saltiel,1 Daniel I Silvershein2 1Department of Psychiatry, New York University School of Medicine/Langone Medical Center New York University Behavioral Health Programs, New York University Pearl Barlow Center for Memory Evaluation and Treatment, New York, NY, USA; 2Department of Medicine, New York University School of Medicine/Langone Medical Center, New York, NY, USA Abstract: Individual patients with depression present with unique symptom clusters – before, during, and even after treatment. The prevalence of persistent, unresolved symptoms and their contribution to patient functioning and disease progression emphasize the importance of finding the right treatment choice at the onset and the utility of switching medications based on suboptimal responses. Our primary goal as clinicians is to improve patient function and quality of life. In fact, feelings of well-being and the return to premorbid levels of functioning are frequently rated by patients as being more important than symptom relief. However, functional improvements often lag behind resolution of mood, attributed in large part to persistent and functionally impairing symptoms – namely, fatigue, sleep/wake disturbance, and cognitive dysfunction. Thus, patient outcomes can be optimized by deconstructing each patient’s depressive profile to its component symptoms and specifically targeting those domains that differentially limit patient function. This article will provide an evidence-based framework within which clinicians may tailor pharmacotherapy to patient symptomatology for improved treatment outcomes. Keywords: MDD, tailored pharmacotherapy, patient-specific profile, individualized pharmacotherapy

DCS TERRAIN SUBMISSION for ONEIDA COUNTY, NEW York, USA

Data.gov (United States)

Federal Emergency Management Agency, Department of Homeland Security — For Oneida County, NY, there were two types of elevation datasets. The first type is LiDAR and the second one is Auto-correlation DEM. Auto-correlation DEM data was...

El Idioma en Nueva York (The Language in New York)

Science.gov (United States)

Hernandez, Amelia

1977-01-01

An interview with the president of the three-year-old Hispanic-American Journalists Association of New York. A summary of the aims and activities of the association and of the strides made in securing the rights of the Spanish-speaking population is given. (Text is in Spanish.) (AMH)

Pulling a patient up in bed

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2017:chap 12. Review Date 11/15/2017 ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

Small bowel resection - discharge

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2017:chap 26. Read More Colon cancer Crohn ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

Getting yourself healthy before surgery

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2016:chap 26. Review Date 9/17/2016 ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

Central venous catheter - flushing

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2016:chap 29. Read More Bone marrow transplant ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

Turning patients over in bed

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2017:chap 12. Review Date 11/15/2017 ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

Nasogastric feeding tube

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2016:chap 16. Ziegler TR. Malnutrition, nutritional assessment, ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

Peripherally inserted central catheter - dressing change

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2016:chap 29. Review Date 11/20/2017 ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

Peripherally inserted central catheter - flushing

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2016:chap 29.6. Read More Bone marrow ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

Central venous catheter - dressing change

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2017:chap 29. Read More Bone marrow transplant ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

Peripherally inserted central catheter - insertion

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2016:chap 29. Review Date 11/20/2017 ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

Wet to dry dressing changes

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2016:chap 25. Patient Instructions Cosmetic breast surgery - ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

Large bowel resection - discharge

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2016:chap 26. Read More Colon cancer Colostomy ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

Total colectomy or proctocolectomy - discharge

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2016:chap 26. Read More Colon cancer Ileostomy ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

The day of your surgery - adult

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2016:chap 26. Review Date 9/17/2016 ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

Bathing a patient in bed

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2017:chap 8. Timby BK. Assisting with basic ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

Moving a patient from bed to a wheelchair

Science.gov (United States)

... to Advanced Skills . 9th ed. New York, NY: Pearson; 2017:chap 12. Timby BK. Assisting with basic ... Bethesda, MD 20894 U.S. Department of Health and Human Services National Institutes of Health Page last updated: ...

Rate Your Risk Quiz

Science.gov (United States)

... Cares Peers Support Ask the Doctor My Food Coach Nutrition Dialysis Patient & Family Resources Emergency Resources A ... State Charity Registration Disclosures © 2017 National Kidney Foundation, Inc., 30 East 33rd Street, New York, NY 10016, ...

Flu Season and Your Kidneys

Science.gov (United States)

... Cares Peers Support Ask the Doctor My Food Coach Nutrition Dialysis Patient & Family Resources Emergency Resources A ... State Charity Registration Disclosures © 2017 National Kidney Foundation, Inc., 30 East 33rd Street, New York, NY 10016, ...

Products for Children with Enuresis and Daytime Urinary Incontinence

Science.gov (United States)

... Cares Peers Support Ask the Doctor My Food Coach Nutrition Dialysis Patient & Family Resources Emergency Resources A ... State Charity Registration Disclosures © 2017 National Kidney Foundation, Inc., 30 East 33rd Street, New York, NY 10016, ...

Kidney Quiz

Science.gov (United States)

... Cares Peers Support Ask the Doctor My Food Coach Nutrition Dialysis Patient & Family Resources Emergency Resources A ... State Charity Registration Disclosures © 2017 National Kidney Foundation, Inc., 30 East 33rd Street, New York, NY 10016, ...

Skin Rashes Due to Bed-Wetting

Science.gov (United States)

... Cares Peers Support Ask the Doctor My Food Coach Nutrition Dialysis Patient & Family Resources Emergency Resources A ... State Charity Registration Disclosures © 2017 National Kidney Foundation, Inc., 30 East 33rd Street, New York, NY 10016, ...

77 FR 13355 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2012-03-06

... Veritas, Consumer Taunton, MA 02/15/12 02/14/12 Product Services, Inc. (Workers). 81337 Fu Sing Fashion...). 81324 CBS Fashion Inc. (Workers). New York, NY 02/13/12 02/10/12 81325 Sykes Enterprise (Workers...

75 FR 74126 - Culturally Significant Objects Imported for Exhibition Determinations: “Picasso: Guitars 1912-1914”

Science.gov (United States)

2010-11-30

... objects at the Museum of Modern Art, New York, NY, from on or about February 13, 2011, until on or [[Page... the United States, are of cultural significance. The objects are imported pursuant to loan agreements...

77 FR 56909 - Culturally Significant Objects Imported for Exhibition Determinations: “Tokyo 1955-70: A New...

Science.gov (United States)

2012-09-14

... the Museum of Modern Art, New York, NY, from on or about November 18, 2012, until on or about February... ``Tokyo 1955-70: A New Avant-Garde,'' imported from abroad for temporary exhibition within the United...

9 CFR 93.103 - Import permits for birds; and reservation fees for space at quarantine facilities maintained by...

Science.gov (United States)

2010-01-01

... Drury Lane, Rock Tavern, NY, 12575, or to the port veterinarian in charge of the New York Animal Import... calendar year in which they are issued. (Approved by the Office of Management and Budget under control...

Arm-associated measurements as estimates of true height in black ...

African Journals Online (AJOL)

arm-associated measurements to true height included that of the World Health ... Conclusion: Findings indicate the need for gender and race-specific height estimation ..... New. York, NY: Springer; 2012. 12. Golshan M, Amra B, Hoghoghi MA.

Trends in Elevated Triglyceride in Adults: United States, 2001-2012

Science.gov (United States)

... Vital and Health Statistics Annual Reports Health Survey Research Methods Conference Reports from the National Medical Care Utilization ... estimation. 2nd ed. New York, NY: Springer Science+Business Media, LLC. 2007. Klein RJ, Schoenborn CA. Age ...

Operational research(ers) in development: Growing a new ...

African Journals Online (AJOL)

working with individual stakeholders to capture their individual cognitive ..... [14] Kelly GA, 1955, The psychology of personal constructs, Norton, New York (NY). ... [26] Scavarda A, Bouzdine-Chameeva T, Goldstein S, Hays J & Hill A, 2006, ...

Phenindamine overdose

Science.gov (United States)

... Goldfrank's Toxicologic Emergencies . 10th ed. New York, NY: McGraw Hill-Medical; 2015:chap 49. Monte AA, Hoppe ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Mercuric oxide poisoning

Science.gov (United States)

... Essentials of Toxicology. 3rd ed. New York, NY: McGraw Hill Medical; 2015:chap 23. Theobald JL, Mycyk ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Pheniramine overdose

Science.gov (United States)

... Goldfrank's Toxicologic Emergencies . 10th ed. New York, NY: McGraw Hill-Medical; 2015:chap 49. Monte AA, Hoppe ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Malignant hypertension

Science.gov (United States)

... of Internal Medicine . 19th ed. New York, NY: McGraw Hill; 2015:chap 341. Shayne P, Lynch CA. ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Lip moisturizer poisoning

Science.gov (United States)

... Science of Poisons . 8th ed. New York, NY: McGraw-Hill Education/Medical; 2013:chap 6. Review Date ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Paradichlorobenzene poisoning

Science.gov (United States)

... Goldfrank's Toxicologic Emergencies . 10th ed. New York, NY: McGraw Hill; 2015:chap 105. Review Date 10/16/ ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Doxepin overdose

Science.gov (United States)

... Goldfrank's Toxicologic Emergencies . 10th ed. New York, NY: McGraw Hill-Medical; 2015:chap 71. Review Date 7/ ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Methylmercury poisoning

Science.gov (United States)

... Goldfrank's Toxicologic Emergencies . 10th ed. New York, NY: McGraw Hill-Medical; 2015:chap 98. Theobald JL, Mycyk ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Copper poisoning

Science.gov (United States)

... Goldfrank's Toxicologic Emergencies . 10th ed. New York, NY: McGraw Hill-Medical; 2015:chap 95. Theobald JL, Mycyk ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Vacation health care

Science.gov (United States)

... in General Medicine . 8th ed. New York, NY: McGraw-Hill; 2012:chap 286. Swanson SJ, John CC. ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Nail polish poisoning

Science.gov (United States)

... Science of Poisons . 8th ed. New York, NY: McGraw-Hill Medical; 2013:chap 24. Kulig K. General ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Ethylene glycol poisoning

Science.gov (United States)

... Essentials of Toxicology . 3rd ed. New York, NY: McGraw-Hill Education; 2015:chap 33. White SR. Toxic ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

78 FR 1713 - Golden Nematode; Removal of Regulated Areas in Livingston and Steuben Counties, NY

Science.gov (United States)

2013-01-09

...-0079] Golden Nematode; Removal of Regulated Areas in Livingston and Steuben Counties, NY AGENCY: Animal... are amending the golden nematode regulations by removing areas in Livingston and Steuben Counties in... areas in these two counties are free of golden nematode, and we have determined that regulation of these...

77 FR 65360 - Grant of Authority for Subzone Status (Centrifugal and Submersible Pumps); Auburn, NY

Science.gov (United States)

2012-10-26

... Status (Centrifugal and Submersible Pumps); Auburn, NY Pursuant to its authority under the Foreign-Trade... authority to establish a special-purpose subzone at the centrifugal and submersible pump manufacturing and... submersible pumps and related controllers at the Xylem Water Systems U.S.A., LLC, facilities located in Auburn...

Orofacial pain management: current perspectives

OpenAIRE

Romero-Reyes, Marcela; Uyanik, James M

2014-01-01

Marcela Romero-Reyes, James M Uyanik Orofacial and Head Pain Service, Department of Oral and Maxillofacial Pathology Radiology and Medicine, New York University College of Dentistry, New York, NY, USA Abstract: Some of the most prevalent and debilitating pain conditions arise from the structures innervated by the trigeminal system (head, face, masticatory musculature, temporomandibular joint and associated structures). Orofacial pain (OFP) can arise from different regions and etiologies. Tem...

2014 USGS CMGP Lidar: Post Sandy (Long Island, NY)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — TASK NAME: Long Island New York Sandy LIDAR lidar Data Acquisition and Processing Production Task USGS Contract No. G10PC00057 Task Order No. G14PD00296 Woolpert...

30 CFR 57.5040 - Exposure records.

Science.gov (United States)

2010-07-01

... National Standards Institute, Inc., at 25 W. 43rd Street, 4th Floor, New York, NY 10036; http://www.ansi..., lunch rooms, magazines and any other place or location where persons work, travel or congregate, and the...

Medline Plus

Full Text Available ... New York, NY, 1/04/2012) Coronary Artery Disease Transradial Approach for Cardiac Catheterization: The New Frontier ... Medical Center, Chicago, IL, 6/26/2014) Heart Diseases Transesophageal Echocardiogram (TEE) (Shawnee Mission Medical Center, Merriam, ...

Medline Plus

Full Text Available ... Circulation Angioplasty Transradial Approach for Cardiac Catheterization: The New Frontier of Coronary Intervention (University of Chicago Medical ... to Treat Obstructive Hypertrophic Cardiomyopathy (HCM) (Roosevelt Hospital, New York, NY, 1/04/2012) Coronary Artery Disease ...

Medline Plus

Full Text Available ... St. Francis Hospital, Greenville, SC, 1/27/2014) Hip Replacement Anterior Approach Revision Hip Surgery (University Hospital, ... Medical Center, New York, NY, 1/11/2008) Hip Replacement Anterior Approach Revision Hip Surgery (University Hospital, ...

Learn about NF

Science.gov (United States)

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Schwannomatosis

Science.gov (United States)

... NF Registry today. LEARN MORE top Children’s Tumor Foundation 120 Wall Street, 16th Floor New York, NY 10005-3904 1-800-323-7938 info@ctf.org © Children's Tumor Foundation - All rights reserved Privacy Policy

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Full Text Available ... Center, New York, NY, 2/13/2008) Heart Health Tests Transesophageal Echocardiogram (TEE) (Shawnee Mission Medical Center, ... Louis, St. Louis, MO, 05/11/2011) Sexual Health Issues Erectile Dysfunction Simultaneous Inflatable Penile Prosthesis (IPP) ...

77 FR 34455 - Culturally Significant Objects Imported for Exhibition Determinations: “Century of the Child...

Science.gov (United States)

2012-06-11

... exhibit objects at The Museum of Modern Art, New York, NY, from on or about July 29, 2012, until on or... exhibition within the United States, are of cultural significance. The objects are imported pursuant to loan...

75 FR 1110 - Culturally Significant Objects Imported for Exhibition Determinations: “Marina Abramovic: The...

Science.gov (United States)

2010-01-08

... objects at the Museum of Modern Art, New York, NY, from on or about March 14, 2010, until on or about May... the United States, are of cultural significance. The objects are imported pursuant to loan agreements...

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Full Text Available ... Florida, Miami, FL, 2/01/2012) Eyes and Vision Glaucoma Innovations in Pediatric Glaucoma Surgery (UAB Callahan ... Special Surgery, New York, NY, 12/11/2013) Computer Guided Knee Replacement (Broward Health North Medical Center, ...

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Full Text Available ... Baptist Hospital, Miami, FL, 10/17/2013) Mastectomy Breast Reconstruction: Deep Inferior Epigastric Perforator (Beth Israel Medical Center, New York, NY, 1/11/2008) Ovarian Cancer Scarless Hysterectomy (Baptist Hospital, Miami, FL, 10/17/ ...

Establishment of a new immortalized human corneal epithelial cell line (iHCE-NY1) for use in evaluating eye irritancy by in vitro test methods.

Science.gov (United States)

Yamamoto, Naoki; Kato, Yoshinao; Sato, Atsushi; Hiramatsu, Noriko; Yamashita, Hiromi; Ohkuma, Mahito; Miyachi, Ei-Ichi; Horiguchi, Masayuki; Hirano, Koji; Kojima, Hajime

2016-08-01

In vitro test methods that use human corneal epithelial cells to evaluate the eye irritation potency of chemical substances do not use human corneal epithelium because it has been difficult to maintain more than four passages. In this study, we make a new cell line comprising immortalized human corneal epithelial cells (iHCE-NY1). The IC50 of iHCE-NY1 cells is slightly higher than that of Statens Seruminstitut Rabbit Cornea (SIRC) cells, which are currently used in some in vitro test methods. CDKN1A in iHCE-NY1 cells was used as a marker of gene expression to indicate cell cycle activity. This enabled us to evaluate cell recovery characteristics at concentrations lower than the IC50 of cytotoxic tests.

SOURCE CHARACTERIZATION AND CONTROL TECHNOLOGY ASSESSMENT OF METHYLENE CHLORIDE EMISSIONS FROM EASTMAN KODAK COMPANY, ROCHESTER, NY

Science.gov (United States)

The report gives results of an assessment of potential control technologies for methylene chloride (also known as dichloromethane or DCM) emission sources at Eastman Kodak Company's Kodak Park facility in Rochester, NY. DCM is a solvent used by Kodak in the manufacture of cellulo...

75 FR 25290 - Notice of Intent To Repatriate Cultural Items: Rochester Museum & Science Center, Rochester, NY

Science.gov (United States)

2010-05-07

... Museum & Science Center, Rochester, NY, that meet the definitions of ``sacred objects'' and ``objects of.... Tonawanda Seneca Nation traditional religious leaders have identified these medicine faces as being needed...-Haudenosaunee consultants, the museum has determined that the medicine faces are both sacred objects and objects...

75 FR 25289 - Notice of Intent To Repatriate Cultural Items: Rochester Museum & Science Center, Rochester, NY

Science.gov (United States)

2010-05-07

... Museum & Science Center, Rochester, NY, that meet the definitions of ``sacred object'' and object of...- 9). They are of Onondaga origin and were made circa 1970. Onondaga Nation traditional religious... that these medicine faces are culturally affiliated with the Onondaga Nation, and are both sacred...

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Full Text Available ... Medical Center, New York, NY, 2/24/2009) Metabolic Problems Genetic Brain Disorders Treating Moyamoya Disease (Children's ... provider and does not provide medical diagnosis or treatment. BroadcastMed only provides visitors to the site with ...

Parkinson's Disease Videos

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Full Text Available ... 1-800-4PD-INFO (473-4636) helpline@parkinson.org Search Our Site General Gift Tribute Gift Moving ... Suite 1509, New York, NY 10018 contact@parkinson.org Press Room Ask a Doctor Sign In Privacy & ...

75 FR 82129 - Culturally Significant Objects Imported for Exhibition Determinations: “Francis Alÿs: A Story of...

Science.gov (United States)

2010-12-29

... exhibit objects at the Museum of Modern Art, New York, NY, from on or about May 8, 2011, until on or about... exhibition within the United States, are of cultural significance. The objects are imported pursuant to loan...

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Full Text Available ... New York, NY, 2/13/2008) Heart Health Tests Transesophageal Echocardiogram (TEE) (Shawnee Mission Medical Center, Merriam, ... health care provider and does not provide medical diagnosis or treatment. BroadcastMed only provides visitors to the ...

Comparing genetic ancestry and self-reported race/ethnicity in a ...

Indian Academy of Sciences (India)

5Department of Oncological Science, Mount Sinai School of Medicine, New York, NY 10029, USA ... admixture in an ethnically diverse population of 396 mothers and 188 of their ... tween cases and controls, may give rise to false associa-.

Public Notice: 2016-05, In the matter of Thomas Electronics, Inc.

Science.gov (United States)

On the date identified below, EPA commenced the following administrative action for the assessment of Administrative civil penalties: in the matter of Ducommun Incorporated, D/B/S Ducommun Aerostructures New York, Inc., 2 Flint Mine Road, Coxsackie, NY

Babesiosis in Lower Hudson Valley, New York

Centers for Disease Control (CDC) Podcasts

2011-05-12

This podcast discusses a study about an increase in babesiosis in the Lower Hudson Valley of New York state. Dr. Julie Joseph, Assistant Professor of Medicine at New York Medical College, shares details of this study.  Created: 5/12/2011 by National Center for Emerging Zoonotic and Infectious Diseases (NCEZID).   Date Released: 5/23/2011.

77 FR 51912 - Safety Zone; Tom Lyons Productions Fireworks, Long Island Sound, Sands Point, NY

Science.gov (United States)

2012-08-28

... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 [Docket Number USCG-2012-0618] RIN 1625-AA00 Safety Zone; Tom Lyons Productions Fireworks, Long Island Sound, Sands Point, NY AGENCY.... 165.T01-0618 to read as follows: Sec. 165.T01-0618 Safety Zone; Tom Lyons Productions Fireworks, Long...

Engineering economic assessment of residential wood heating in NY

Science.gov (United States)

We provide insight into the recent resurgence in residential wood heating in New York by: (i) examining the lifetime costs of outdoor wood hydronic heaters (OWHHs) and other whole-house residential wood heat devices,(ii) comparing these lifetime costs with those of competing tech...

78 FR 60009 - Environmental Impact Statement: Erie and Genesee Counties, New York

Science.gov (United States)

2013-09-30

... and Genesee Counties, New York AGENCY: Federal Highway Administration (FHWA), DOT; New York State... counties of Erie and Genesee, New York (NYSDOT Project Identification Number: 5528.28). A Notice of Intent... CONTACT: Jonathan McDade, Division Administrator, Federal Highway Administration, New York Division, Leo W...

Selected Papers from the 1982 Conference "New York Writes: Kindergarten through College" (New York, New York, April 3, 1982).

Science.gov (United States)

Kwalick, Barry, Ed.; And Others

Presenting sound instructional strategies and writing theories, these proceedings of a conference held at Marymount Manhattan College address the needs of writing teachers at all educational levels. Following an introduction outlining the conference and the "New York Writes" project, the keynote address discusses the renewed interest in…

78 FR 50108 - Notice of Intent To Repatriate Cultural Item: Rochester Museum & Science Center, Rochester, NY

Science.gov (United States)

2013-08-16

....R50000] Notice of Intent To Repatriate Cultural Item: Rochester Museum & Science Center, Rochester, NY AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Rochester Museum & Science Center... that the cultural item listed in this notice meets the definition of a sacred object and an object of...

75 FR 23801 - Notice of Intent to Repatriate Cultural Items: Rochester Museum & Science Center, Rochester, NY

Science.gov (United States)

2010-05-04

... Museum & Science Center, Rochester, NY, that meet the definitions of ``sacred objects'' and ``objects of... center of the Seneca religious fire. This was agreed upon by representatives from the Seneca Nation of.... Tonawanda Seneca Nation traditional religious leaders have identified these medicine faces as being needed...

77 FR 38488 - Safety Zone; Alexandria Bay Chamber of Commerce, St. Lawrence River, Alexandria Bay, NY

Science.gov (United States)

2012-06-28

... 1625-AA00 Safety Zone; Alexandria Bay Chamber of Commerce, St. Lawrence River, Alexandria Bay, NY... restrict vessels from a portion of the St. Lawrence River during the Alexandria Bay Chamber of Commerce... of proposed rulemaking (NPRM) entitled Safety Zone; Alexandria Bay Chamber of Commerce, St. Lawrence...

33 CFR 110.60 - Captain of the Port, New York.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Captain of the Port, New York... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.60 Captain of the Port, New York. (a) Western... point of origin. (d) New York Harbor. (1) Newark Bay, Southeast. All waters bound by the following...

New York State's COSH Movement: A Brief History.

Science.gov (United States)

Lax, Michael

2018-01-01

Unions, health and safety activists, and professionals came together to create Coalitions for Occupational Safety and Health (COSH groups) in a number of cities across the United States beginning in the 1970s. The COSHes have played an important and unique role in advocating worker health and safety since that time, through activities including technical assistance, training and education, and campaigns on workplace and public policies. In New York State, activist coalitions created eight COSH groups distributed around the state. This paper presents a history of New York's COSHes based on interviews with key participants. The interviews shed light on the origins of the COSH movement in New York, the development and activities of the COSHes, and the organizational trajectory of individual New York COSHes in response to both extra and intraorganizational challenges. Participants' accounts of these issues may be useful for those seeking to sustain the COSH movement.

The Higher Illiteracy

Science.gov (United States)

Lyons, Gene

1976-01-01

Relates the declining literacy among college students to institutional factors and traditions in English departments which devalue undergraduate composition instruction. Available from: Harper's Magazine Company, Two Park Ave., New York, N.Y. 10016, Subscriptions; $8.97 per year. (AA)

Puncture Wounds: First Aid

Science.gov (United States)

... Skin problems. In: American Medical Association Handbook of First Aid and Emergency Care. New York, N.Y.: Random House; 2009. Jan. 12, 2018 Original article: http://www.mayoclinic.org/first-aid/first-aid-puncture-wounds/basics/ART-20056665 . Mayo ...

76 FR 9555 - Procurement List; Additions and Deletions

Science.gov (United States)

2011-02-18

...-8067--Inkjet printer cartridge. NPA: Alabama Industries for the Blind, Talladega, AL. Contracting... Services Administration, New York, NY. Service Service Type/Location: Eyewear Prescription Service...: Winston-Salem Industries for the Blind, Inc., Winston- Salem, NC. Contracting Activity: Department of...

10 CFR Appendix A to Subpart A of... - Metropolitan Statistical Areas/Consolidated Metropolitan Statistical Areas With 1980 Populations...

Science.gov (United States)

2010-01-01

... Evansville-Henderson MSA IN-KY Fort Wayne MSA IN Fresno MSA CA Grand Rapids-Muskegon-Holland MSA MI... MSA LA New York-N. New Jersey-Long Island CMSA NY-NJ-CT-PA Norfolk-Virginia Beach-Newport News MSA VA...

78 FR 46855 - Safety Zone; East End Maritime Foundation Fireworks Display, Greenport Harbor, Greenport, NY

Science.gov (United States)

2013-08-02

... 1625-AA00 Safety Zone; East End Maritime Foundation Fireworks Display, Greenport Harbor, Greenport, NY... temporary rule proposes to establish a safety zone for the East End Maritime Foundation fireworks display....1. 0 2. Add Sec. 165.T01-0600 to read as follows: Sec. 165.T01-0600 Safety Zone; East End Maritime...

New York 2010 Lidar Coverage, USACE National Coastal Mapping Program

Data.gov (United States)

Army Corps of Engineers, Department of the Army, Department of Defense — The Joint Airborne Lidar Bathymetry Technical Center of Expertise (JALBTCX) has performed a coastal survey along the Atlantic coast of NY in 2010. The data types...

New York 2005 Lidar Coverage, USACE National Coastal Mapping Program

Data.gov (United States)

Army Corps of Engineers, Department of the Army, Department of Defense — The Joint Airborne Lidar Bathymetry Technical Center of Expertise (JALBTCX) has performed a coastal survey along the Atlantic coast of NY in 2005. The data types...

Division Artillery: Linking Strategy to Tactics

Science.gov (United States)

2017-05-25

1 Sean MacFarland, Michael Shields, and Jefferey Snow, The King and I: The Impending Crisis in the Field Artillery’s Ability to Provide...New York: Holt, 2003), 305-312; Boyd Dastrup, King of Battle: A Branch History of the US Army’s Field Artillery, 1992, 209; Carlo D’Este, World War...Strategic Plan for the Persian Gulf War (New York, NY: Naval Institute Press, 2008), 60. 56 US Army, Third Armored Division Artillery Historical

America’s Transitional Capacity: War, Systems, and Globalization

Science.gov (United States)

2013-05-23

alleviate human suffering. Amartya Sen supports the Wilsonian philosophy by pointing out that 44Mead, 131. 45Ibid., 103. 46Mead, 164-7. 19...E. Fiasco: the American Military Adventure in Iraq, 2003 to 2005. Reprint ed. New York, NY: Penguin Books, 2007. Sen , Amartya . Development as...they produced a large naval forces in order to expand trade markets and ensure 47Amartya Sen , Development as Freedom (New York: Anchor Books, 1999

FAA-NASA Sixth International Conference on the Continued Airworthiness of Aircraft Structures

Science.gov (United States)

1995-12-01

Administration, and Colin G. Drury , State University of New York at Buffalo The Aging Aircraft Nondestructive Inspection Validation Center - A R esource for...William T. Shepherd FAA-Office of Aviation Medicine Washington, DC and Colin G. Drury State University of New York at Buffalo Buffalo, NY INTRODUCTION FAA’s...improvement, changing the task, the operator (inspector), machine, or environment as appropriate, e.g., review in Drury , 1992 (Ref. 1). 2. From the

United States Federal Guidance on Witness Protection in Human Trafficking

Science.gov (United States)

2015-06-12

York Hotel and Towers, New York, NY, 25 September 2012), accessed 21 March 2015, http://www.whitehouse.gov/the-press- office/2012/09/ 25/remarks...with law enforcement for greater societal good will not come before the satisfaction of more basic human survival needs, including protection from...of Homeland Security (DHS) DHS: Immigration and Customs Enforcement (ICE) Investigations (22 U.S.C. 7110(i)) $18.0 $10.0 DHS: Human Smuggling and

Generating Natural Language Under Pragmatic Constraints.

Science.gov (United States)

1987-03-01

Computation and Mathematics Department Bethesda, Maryland 20084 Captain Grace M. Hopper, USNR I copy Naval Data Automation Command, Code OOH Washington Navy...Institute Mathematical Science New York University New York, NY 10012 Dr. Morgan I copy University of Pennsylvania Dept. of Computer Science & Info. Sci...If mi initerpretatioi wvith the group’s concepts i 4hut Alrealdv present ili mlemory. ,1 lew higzh- lvel interpretltion cii 1e created and indexed off

Energy Optimization Assessment at U.S. Army Installations: West Point Military Academy, NY

Science.gov (United States)

2008-09-01

chillers to work unnecessarily more than needed. Other buildings had setpoints at different areas above 55 °F. Many buildings are air-conditioned and... optimal . The cost of 12.5 cents/KWh makes it unlikely, especially where steam adsorption chillers exist. 11.8.2 Solution Use the existing steam...ER D C/ CE R L TR -0 8 -1 4 Energy Optimization Assessment at U.S. Army Installations West Point Military Academy, NY David M

Aflibercept: a review of its use in the treatment of choroidal neovascularization due to age-related macular degeneration

Directory of Open Access Journals (Sweden)

Balaratnasingam C

2015-12-01

Full Text Available Chandrakumar Balaratnasingam,1–3 Elona Dhrami-Gavazi,1,2,4 Jesse T McCann,1,2,4,5 Quraish Ghadiali,1,2 K Bailey Freund1,2,4,5 1Vitreous-Retina-Macula Consultants of New York, NY, USA; 2LuEsther T Mertz Retinal Research Center, Manhattan Eye, Ear and Throat Hospital, New York, NY, USA; 3Centre for Ophthalmology and Visual Sciences, Lions Eye Institute, University of Western Australia, Perth, WA, Australia; 4Department of Ophthalmology, Edward S Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, NY, USA; 5Department of Ophthalmology, New York University School of Medicine, New York, NY, USA Abstract: Choroidal neovascularization (CNV due to age-related macular degeneration (AMD is an important cause of visual morbidity globally. Modern treatment strategies for neovascular AMD achieve regression of CNV by suppressing the activity of key growth factors that mediate angiogenesis. Vascular endothelial growth factor (VEGF has been the major target of neovascular AMD therapy for almost two decades, and there have been several intravitreally-administered agents that have enabled anatomical restitution and improvement in visual function with continual dosing. Aflibercept (EYLEA®, initially named VEGF Trap-eye, is the most recent anti-VEGF agent to be granted US Food and Drug Administration approval for the treatment of neovascular AMD. Biologic advantages of aflibercept include its greater binding affinity for VEGF, a longer intravitreal half-life relative to other anti-VEGF agents, and the capacity to antagonize growth factors other than VEGF. This paper provides an up-to-date summary of the molecular mechanisms mediating CNV. The structural, pharmacodynamic, and pharmacokinetic advantages of aflibercept are also reviewed to rationalize the utility of this agent for treating CNV. Results of landmark clinical investigations, including VIEW 1 and 2 trials, and other important studies are then summarized and used to

New York 2011 Lidar Coverage, USACE National Coastal Mapping Proram

Data.gov (United States)

Army Corps of Engineers, Department of the Army, Department of Defense — The Joint Airborne Lidar Bathymetry Technical Center of Expertise (JALBTCX) has performed a coastal survey along the NY coasts of Lake Erie and Lake Ontario in 2011....

New York state high-speed surface transportation study: Final report

Energy Technology Data Exchange (ETDEWEB)

1994-08-01

In 1990, New York State Governor Mario M. Cuomo created an interagency task force under the leadership of Lt. Governor Stan Lundine to investigate the potential of high speed ground transportation (HSGT) systems. Building on information from previous agency activities, including consultant efforts contracted by the New York State Energy Research and Development Authority (NYSERDA), the New York State Thruway Authority (NYSTA), and in-house analyses performed by New York State Department of Transportation (NYSDOT), the task force focused on the corridor between New York City and the Niagara Frontier. In December 1991, NYSERDA issued a contract for a study of high speed ground transportation options for New York State. The study`s objective was to assess potential rights-of-way, ridership, energy and environmental impacts, economic benefits, capital, operating, and maintenance costs, and financial viability of HSGT systems. This study builds upon and supplements previous and on-going HSGT activities conducted by the members of the interagency task force. These activities include: Maglev Technical and Economic Feasibility Study (NYSERDA); Maglev Demonstration Site Investigation (NYSTA); and New York/Massachusetts High Speed Ground Transportation Study (NYSDOT). This study is intended to verify and refine previous information and analyses and provide supplemental information and insights to be used in determining if additional investigation and activities involving HSGT are desirable for New York State. This study evaluates HSGT technologies capable of speeds significantly higher than those achieved with the present rail system. Three HSGT categories are used in this study: incremental rail improvement, very high-speed rail, and Maglev.

The Duke of York visits CERN

CERN Multimedia

2004-01-01

The Duke of York chats before inaugurating the UK@CERN exhibition. From left to right: Robert Aymar, CERN's Director General, the Duke of York, and leading UK scientists at CERN: Jim Virdee, CMS deputy spokeman; theorist John Ellis ; and Steve Myers, head of the AB Department. On 23 November, the Duke of York visited CERN and, in his capacity as the UK's Special Representative for International Trade and Investment, inaugurated the UK@CERN Exhibition. This biennial trade show was initially held in 1968, the first such exhibition by a CERN member state. This year 22 companies displayed goods and services that could be of interest to CERN scientists. In his inaugural speech, the Duke emphasized that business between companies and CERN "is a two-way information flow with mutual benefits." The companies make sales but also benefit from technologies that CERN transfers to them. CERN benefits from the exchange, the Duke said, addressing CERN's scientists, because it "frees your time for what you do best: science....

MAGE-A1, GAGE and NY-ESO-1 cancer/testis antigen expression during human gonadal development

DEFF Research Database (Denmark)

Gjerstorff, Morten F; Kock, Kirsten; Nielsen, Ole

2007-01-01

BACKGROUND: Cancer/testis antigens (CTAs) are expressed in several cancers and during normal adult male germ cell differentiation. Little is known about their role in fetal development of human germ cells. METHODS: We examined expression of the CTAs MAGE-A1, GAGE and NY-ESO-1 in fetal gonads...

75 FR 40851 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Connected Media...

Science.gov (United States)

2010-07-14

... of antitrust plaintiffs to actual damages under specified circumstances. Specifically, Warner Music Group, New York, NY; Push Entertainment LTD., Bath, UNITED KINGDOM; MOD Systems Incorporated, Seattle, WA; PacketVideo Corporation, San Diego, CA; BACH Technology AS, Bergen, NORWAY; Sony Corporation of...

Medline Plus

Full Text Available ... Roosevelt Hospital, New York, NY, 1/04/2012) Coronary Artery Disease Transradial Approach for Cardiac Catheterization: The New Frontier ... Center, Winston-Salem, NC, 09/17/2015) Seniors Coronary Artery Disease Transradial Approach for Cardiac Catheterization: The New Frontier ...

Function and safety assessment of Lactococus lactis subsp. lactis ...

African Journals Online (AJOL)

STORAGESEVER

2008-11-19

Nov 19, 2008 ... important to develop new ways of reducing serum ... times prior to use in present study. ... Ltd.(China); Kit ... added to the media in order to mimic conditions that would be ...... John Wiley & Sons, New York, NY, USA; pp.

NATO Strategy and Out-of-Area Operations

Science.gov (United States)

2010-12-02

The End of Alliances, Reprint ed. (New York: Oxford University Press, USA, 2008), 92-95. Jeremy Pressman , Warring Friends: Alliance Restraint in...and-pakistan (accessed November 20, 2010). Pressman , Jeremy. Warring friends: Alliance Restraint in International Politics. Ithaca, NY: Cornell

77 FR 42640 - Safety Zone; Can-Am Festival Fireworks, Black River Bay, Sackets Harbor, NY

Science.gov (United States)

2012-07-20

...-AA00 Safety Zone; Can-Am Festival Fireworks, Black River Bay, Sackets Harbor, NY AGENCY: Coast Guard... Black River Bay during the Can-Am Festival Fireworks display. This temporary safety zone is necessary to... Can-Am Festival Fireworks. This zone will be effective and enforced from 9:15 p.m. until 10:45 p.m. on...

Udvikling af en internetsøgestrategi til identifikation af ny medicinsk teknologi inden for prostatacancer

DEFF Research Database (Denmark)

Thygesen, Marianne; Vondeling, Hindrik; Douw, Karla

2007-01-01

internetsider efter efficiens. Her er efficiens forstået som mindst antal minutter brugt pr. fund af information om en ny væsentlig medicinsk teknologi. Resultater: Strategien består af ti sider, som bør benyttes i følgende rækkefølge: YahooHealth, DoctorsGuide, The National Electronic Library for Medicines...

The New York State optometry workforce study.

Science.gov (United States)

Soroka, Mort

2012-04-01

This study presents an analysis of the current optometry workforce, both as a unique profession and more broadly within the context of all eye care providers (optometry and ophthalmology) in New York State. The supply and distribution of eye care practitioners provides useful information for policy makers while providing insights as to the impact of the one optometry school within the state. Several databases were employed and a web based survey was developed for completion by all optometrists. The questionnaire included demographic data, whether they were actively practicing in New York State or any other state, were they full time or part time, their primary mode of practice, or if they provided care within institutional settings. Access to care was gauged by the respondents' availability for appointments during evenings or weekends. Access to eye care services in New York State has improved significantly during the past 30 years as the supply of optometrists increased. Before this study was conducted it was generally believed that there were more optometrists than ophthalmologists in every state of the nation except New York, Maryland and the District of Columbia. Findings of this study demonstrate there are 37% more optometrists in New York State than ophthalmologists and more evenly distributed as optometrists are located in almost every county of the state. Sixteen counties have no ophthalmologists. This is attributed to the presence of the College of Optometry established in 1971. More than 60% of all optometrists in the state are SUNY College of Optometry graduates.

75 FR 23800 - Notice of Intent to Repatriate a Cultural Item: Rochester Museum & Science Center, Rochester, NY

Science.gov (United States)

2010-05-04

... Museum & Science Center, Rochester, NY, that meets the definitions of ``sacred object'' and object of... responsibility within the Haudenosaunee Confederacy to bring back national cultural patrimony and sacred objects... not have the authority to do so. Furthermore, Onondaga Nation traditional religious leaders have...

75 FR 23799 - Notice of Intent to Repatriate a Cultural Item: Rochester Museum & Science Center, Rochester, NY

Science.gov (United States)

2010-05-04

... Museum & Science Center, Rochester, NY, that meets the definitions of ``sacred object'' and object of... responsibility within the Haudenosaunee Confederacy to bring back national cultural patrimony and sacred objects... not have the authority to do so. Furthermore, Onondaga Nation traditional religious leaders have...

Negative differential resistance and switch behavior of T-BxNy (x, y = 5, 6, 11) molecular junctions

Science.gov (United States)

Wang, Shi-Liang; Yang, Chuan-Lu; Wang, Mei-Shan; Ma, Xiao-Guang; Xin, Jian-Guo

2017-05-01

The electronic transport properties of T-BxNy (x, y = 5, 6, 11) molecular junction are investigated based on first-principle density functional theory and non-equilibrium Green's function method. Strong negative differential resistance (NDR) behavior is observed for T-B5N6 molecule under negative and positive bias voltages, with an obvious switch effect for T-B6N5. However, only small NDR is shown for the complex of the two molecules. The projected device density of states, the spatial distribution of molecular orbitals, and the effect of transmission spectra under various bias voltages on the electronic transport properties are analyzed. The obvious effect of bias voltage on the changes in the electronic distribution of frontier molecular orbitals is responsible for the NDR or switch behavior. Therefore, different functional molecular devices can be obtained with different structures of T-BxNy.

Efficacy and tolerability of a large scale change in regimen from latanoprost to travoprost in glaucoma patients at the Manhattan Veterans Administration Hospital

Directory of Open Access Journals (Sweden)

Edmund P Farris

2008-06-01

Full Text Available Edmund P FarrisNew York University, New York, NY; Manhattan Veterans Administration Hospital, New York, NY; New York Medical College, Valhalla, NY, USAObjective: This retrospective study was designed to investigate the efficacy and tolerability of travoprost 0.004% substituted for latanoprost 0.005% in glaucoma patients at the Manhattan Veterans Administration Hospital.Research design and methods: We conducted a chart review of patients with stable intraocular pressure (IOP undergoing a formulary change in regimen from latanoprost 0.005% to travoprost 0.004%. Diagnoses included primary open angle glaucoma, ocular hypertension, pigment dispersion glaucoma, and pseudoexfoliation glaucoma. Main outcome measures: The primary outcome measures were IOP change between baseline and 6 months and patient-reported adverse events throughout the study.Results: In the single therapy group (N = 60 eyes, the mean baseline IOP on latanoprost was 15.8 mmHg; after 6 months on travoprost, it was 14.9 mmHg (p < 0.1. In the concomitant therapy group (N = 126 eyes, the mean baseline IOP was 16.7 mmHg; after 6 months on travoprost, it was 15.9 mmHg (p < 0.01. A reduction of IOP ≥ 3 mmHg occurred in 28 eyes of 21 patients at 6 months. An increase of IOP ≥ 3 mmHg occurred in 5 eyes of 4 patients at 6 months. One patient was switched back to latanoprost due to irritation at 3 months. No other patient-reported adverse events, including increased hyperemia, were observed throughout the follow-up period.Conclusions: A change in therapeutic regimen from latanoprost 0.005% to travoprost 0.004% maintained IOP control in stable patients, and in some produced a further reduction in IOP. A change in therapy from latanoprost to travoprost was effective and well-tolerated for the glaucoma patients in this study.Keywords: glaucoma, intraocular pressure, prostaglandin analogue, retrospective studies, travoprost, latanoprost

Geomorphic Analysis of Mattituck Inlet and Goldsmith Inlet, Long Island, New York

National Research Council Canada - National Science Library

Morgan, Michael J; Kraus, Nicholas C; McDonald, Jodi M

2005-01-01

This study of Mattituck Inlet and Goldsmith Inlet, Long Island, NY, covers the historic and geomorphic background, literature, field measurements, numerical modeling of tidal circulation, and analysis...

Surficial geology of Hannibal Quadrangle, Oswego County, New York

Science.gov (United States)

Miller, Todd S.

1981-01-01

The location and extent of 10 kinds of surficial deposits in part of Hannibal quadrangle, Oswego County, N.Y., are mapped on a 7.5-minute U.S. Geological Survey topographic map. The map was compiled to indicate the lithology and potential for ground-water development at any specific location. (USGS)

Evaluating the impact of three incentive programs on the economics of cofiring willow biomass with coal in New York State

International Nuclear Information System (INIS)

Tharakan, P.J.; Volk, T.A.; Lindsey, C.A.; Abrahamson, L.P.; White, E.H.

2005-01-01

Plantations of fast-growing willow shrubs are being promoted as a source quality biomass feedstock for bioenergy and bioproducts in New York State (NY). In the near-term, cofiring of the feedstock--in combination with other woody biomass--with coal in existing utility power boilers is considered to be the most promising conversion method for energy generation. Despite the clear technological viability and associated environmental benefits, cofiring of willow has not been widely adopted. The relatively high production cost of the willow feedstock, which is over twice that of coal, is the primary reason for this lack of interest. Taxes that account for some of the social costs of using coal and/or incentives that appropriate value for some of the social benefits of using willow are essential for eliminating most or the entire current price differential. This paper presents an integrated analysis of the economics of power generation from cofiring willow biomass feedstock with coal, from the perspective of the grower, aggregator and the power plant. Emphasis is placed on analyzing the relative impact of a green premium price, a closed-loop biomass tax credit, and payments to growers under the proposed Conservation Reserve Program (CRP) harvesting exemption policy. The CRP payments reduced the delivered cost of willow by 36-35%, to $1.90 GJ -1 and $1.70 GJ -1 , under current and increased yield conditions, respectively. These prices are still high, relative to coal. Other incentives are required to ensure commercial viability. The required levels of green premium price (0.4-1.0 cents kWh -1 ) and biomass tax credit (0.75-2.4 cents kWh -1 ) vary depending on whether the incentives were being applied by themselves or in combination, and whether current yield or potential increased yields were being considered. In the near term, cofiring willow biomass and coal can be an economically viable option for power generation in NY if the expected overall beneficial effects

NY-ESO-1- and survivin-specific T-cell responses in the peripheral blood from patients with glioma

DEFF Research Database (Denmark)

Liu, Zhenjiang; Poiret, Thomas; Persson, Oscar

2018-01-01

The prognosis for patients with glioblastoma is grim. Ex vivo expanded tumor-associated antigen (TAA)-reactive T-cells from patients with glioma may represent a viable source for anticancer-directed cellular therapies. Immunohistochemistry was used to test the survivin (n = 40 samples) and NY-ESO...

The BID`s of New York

DEFF Research Database (Denmark)

Jensen, Ole B.

, the aim is to present a theoretical and analytical framework for understanding such ? urban mini territories? both in relation to urban power an politics, and in relation to the spatial layout of such forms of urban intervention. In section two the paper shortly describe the phenomenon of New York BIDs....... In the third part of the paper empirical field data from selected New York BIDs are presented. Finally the paper ends with a section in which concluding remarks will be accompanied by reflections on the comparative similarities and differences to European cities....

Original Research Original Research

African Journals Online (AJOL)

RAGHAVENDRA

Language and Art Studies, Institute of Language Studies and Journalism,. Wollega University, Post Box No: 395, Nekemte, Ethiopia ... tudies and Journalism,. Article Information. Article History: Received : 11-04-2015 ..... Teaching by principles: An interactive approach to language pedagogy. New York, NY: Addison.

Drama Therapies in Hospitals

Science.gov (United States)

Goodman, Judith; Prosperi, Mario

1976-01-01

Explores the use of drama as a therapeutic tool at various hospitals and records specific therapy groups dialogues. Available from: The Drama Review, 51 West 4th Street, Room 300, New York, N.Y. 10012. Subscription Rates: $12.50 per year. (MH)

Validation of a tuber blight (Phytophthora infestans) prediction model

Science.gov (United States)

Potato tuber blight caused by Phytophthora infestans accounts for significant losses in storage. There is limited published quantitative data on predicting tuber blight. We validated a tuber blight prediction model developed in New York with cultivars Allegany, NY 101, and Katahdin using independent...

76 FR 35476 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance and...

Science.gov (United States)

2011-06-17

...' industry (i.e., conditions within the industry are adverse). Affirmative Determinations for Worker...' industry are not adverse. None. Negative Determinations for Worker Adjustment Assistance and Alternative...,095; 6ixSigma Apparel Network, LLC, New York, NY. The investigation revealed that criteria of Section...

Teacher Structure as a Predictor of Students' Perceived Competence and Autonomous Motivation: The Moderating Role of Differentiated Instruction

Science.gov (United States)

Guay, Frédéric; Roy, Amélie; Valois, Pierre

2017-01-01

Background: An important pedagogical practice is the provision of structure (Farkas & Grolnick, 2010, "Motiv. Emot.," 34, 266). According to self-determination theory (SDT; Deci & Ryan, 1985, "Intrinsic motivation and self-determination in human behavior," Plenum, New York, NY), structure allows students to develop…

78 FR 9823 - Air Quality: Revision to Definition of Volatile Organic Compounds-Exclusion of a Group of Four...

Science.gov (United States)

2013-02-12

... and H.L. Miller (eds.)]. Cambridge University Press, Cambridge, United Kingdom and New York, NY, USA..., Mail Code (C539-01), Environmental Protection Agency, Research Triangle Park, N.C. 27711; telephone..., Environmental Science & Technology, University of California, Riverside, May 1997; (2) ``Hydrofluoropolyethers...

FERMI: A Flexible Expert Reasoner with Multi-Domain Inferencing.

Science.gov (United States)

1985-07-29

for Life Sciences University of Leyden AFOSR Education Research Center Boiling AFB Boerhaavelaan 2 Washington. DC 20032-6448 2334 EN Leyden The... Kathleen McKeown Columbia University Dr. Michael Levine Department of Computer Science Educational Psychology New York, NY 10027 210 Education Bldg

Fulltext PDF

Indian Academy of Sciences (India)

Srimath

Osamu Shimomura, Marine Biological Laboratory (MBL), Woods Hole, MA, USA. Boston University Medical School, Massachusetts, MA, USA. Martin Chalfie, Columbia University, New York, NY, USA. Roger Y Tsien, University of California, San Diego, CA, USA; Howard Hughes. Medical Institute. Physiology or Medicine.

Review: Derek R. Peterson, Kodzo Gavua, and Ciraj Rassool (eds, The Politics of Heritage in Africa: Economies, Histories, and Infrastructures (2015

Directory of Open Access Journals (Sweden)

Reinhart Kößler

2015-01-01

Full Text Available Review of the edited volume:Derek R. Peterson, Kodzo Gavua, and Ciraj Rassool (eds, The Politics of Heritage in Africa: Economies, Histories, and Infrastructures, London: International African Institute; New York, NY: Cambridge University Press, 2015, ISBN 9781107094857, 291 pages

Assisting New York Dairy Farms with Preparing for OSHA Safety Inspections.

Science.gov (United States)

Tinc, Pamela J; Carrabba, Jim; Meyerhoff, Anna; Horsman, Melissa

2018-01-01

In 2013, the Occupational Safety and Health Administration announced a Local Emphasis Program targeted at New York farmers. This program involved random inspections of dairy farms across the state. This article provides an overview of the efforts made in New York to prepare farmers for these inspections. As a result of this program launch, several safety services offered by the New York Center for Agricultural Medicine and Health were significantly impacted, and required expansion and modification in order to meet the needs of New York farmers.

Distracted pedestrian sustains orbital fracture while on cell phone

OpenAIRE

Edell, Aim?e R; Jung, Jesse J; Solomon, Joel M; Palu, Richard N

2013-01-01

Aimée R Edell, Jesse J Jung, Joel M Solomon, Richard N Palu Department of Ophthalmology, New York University School of Medicine, New York, NY, USA Abstract: Use of cell phones in the general population has become increasingly commonplace. The distracting effects of cell phones among automobile drivers are well established, and legislation prohibits the use of handheld cell phones while driving in several states. Recent research has focused on the similar distracting effects of cel...

Management of ocular inflammation and pain following cataract surgery: focus on bromfenac ophthalmic solution

OpenAIRE

Cho, Hyung; Wolf, Kenneth J; Wolf, Eric J

2009-01-01

Hyung Cho1, Kenneth J Wolf1, Eric J Wolf21Department of Ophthalmology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York, USA; 2Department of Ophthalmology, Edward S. Harkness Eye Institute of Columbia University College of Physicians and Surgeons, New York, NY, USAAbstract: Recently, several new ophthalmic NSAID products have been introduced for commercial use in the United States. The purpose of this review is to briefly overview the ophthalmic NSAIDs currently...

Critical appraisal of belatacept for prophylaxis of rejection in kidney transplant patients

OpenAIRE

Chandraker, Anil; Gabardi,Steven; Martin,Spencer; Tsapepas,

2011-01-01

Spencer T Martin1, Demetra Tsapepas1, Steven Gabardi2–5, Anil Chandraker2,31Department of Pharmacy, New York-Presbyterian Hospital, New York City, NY, USA; 2Harvard Medical School, Boston, MA, USA; 3Renal Division, 4Department of Pharmacy Services, 5Department of Transplant Surgery, Brigham and Women's Hospital, Boston, MA, USAAbstract: Belatacept (LEA29Y) is an intravenous biologic for long-term maintenance immunosuppressive therapy in renal transplant recipients. It is cur...

Modeling Relevant to Safe Operations of U.S. Navy Vessels in Arctic Conditions: Physical Modeling of Ice Loads

Science.gov (United States)

2016-06-01

Proceedings of the ASME 31st International Conference on Ocean, Offshore and Arctic Engineering, 1–6 July, Rio de Janeiro , Brazil, 6:495–505. New York...Arctic Engineering, 1–6 July, Rio de Janeiro , Brazil, 6:495–505. New York, NY: American Society of Mechanical Engineers. doi:10.1115/OMAE2012-83927...of ice impacts with Navy ships. These large-scale tests will provide important benchmark data to support the de - velopment of numerical testbeds

Social capital and cigarette smoking among Latinos in the United States

OpenAIRE

Li, Shijian; Horner, Pilar; Delva, Jorge

2012-01-01

Shijian Li1, Pilar Horner2, Jorge Delva31School of Medicine, New York University, New York, NY, USA; 2School of Social Work, Julian Samora Research Institute, Michigan State University, East Lansing, MI, USA; 3School of Social Work, University of Michigan, Ann Arbor, MI, USA.Abstract: This paper presents the results of analyses conducted to examine if social capital indicators were associated with current cigarette smoking and with quitting smoking among a national representative sample of La...

PUBLIC POLICY VIOLATION UNDER NEW YORK CONVENTION

Directory of Open Access Journals (Sweden)

Michelle Ayu Chinta Kristy

2013-04-01

Full Text Available The increasing number of the use of arbitration in Asia has highlighted the significant influence of the recognition and enforcement of arbitral awards. The New York Convention currently becomes the most widely accepted convention to which the courts would refer when recognizing and enforcing foreign arbitral awards. This article would firstly provide a comparative study of the court’s interpretation towards public policy as mentioned under Article V (2 b of the New York Convention between non-arbitration-friendly-law Indonesia and arbitration-friendly-law China. Subsequently, it will discuss whether uniformity in interpreting and reserving public policy is required or not. Peningkatan jumlah penggunaan lembaga arbitrasi di Asia mendorong peningkatan signifikansi pengakuan dan pelaksanaan putusan arbitrasi asing. Konvensi New York saat ini menjadi konvensi yang diterima secara luas dimana dijadikan referensi oleh pengadilan dalam hal pengakuan dan pelaksanaan putusan arbitrasi asing. Artikel ini akan pertama-tama membahas studi perbandingan atas interpretasi pengadilan mengenai penggunaan kebijakan publik sebagaimana tertera pada Pasal V (2 b Konvensi New York antara Indonesia yang hukumnya tidak mendukung dan China dengan hukum yang mendukung pengakuan dan pelaksanaan putusan arbitrasi asing. Apakah keseragaman antar negara dalam menginterpretasi dan menggunakan kebijakan publik diperlukan atau tidak dibahas pada diskusi selanjutnya.

Some reflections upon Internet TV in the Brazilian context

Science.gov (United States)

de Lima-Lopes, Rodrigo

2016-10-01

Negroponte [1996. Being digital (1st ed.). New York, NY: Vintage Books] discusses the migration television might take from its air-based broadcasting to the digital environment. This paper takes into consideration the exercise in futurology made by Negroponte [1996. Being digital (1st ed.). New York, NY: Vintage Books] as an inspiration to discuss which Internet TV models are currently adopted in Brazil. They are studied in terms of the platforms used and the nature of the channels available. Results show that a number of devices can be used for Internet TV; some channels are redundant, since they are present in more than one context. There are a number of foreign (broadcasting in their own language) and Brazilian channels that seem to be exclusive in each device. Due to the price of some devices, as well as some issues regarding connectivity in Brazil, some platforms seem to lack local production.

Integrating Social Justice into the Practice of CBFT: A Critical Look at Family Schemas.

Science.gov (United States)

Parker, Elizabeth O; McDowell, Teresa

2017-07-01

Many families come to therapy struggling with the negative consequence of social inequity. Family therapy modalities have been developed to address these negative consequences and attend to power and social equity (Transformative family therapy: Just families in a just society. Boston, MA: Pearson Education; Socio-emotional relationship therapy. New York, NY: Springer). We argue that many family therapy modalities can be adapted to include social equity (Applying critical social theory in family therapy practice. AFTA Springer Series. New York, NY: Springer Publishing). Specifically, cognitive behavioral family therapy can be used to address the inequality in social systems that negatively affect the family system. We focus on schema formation and suggest an emphasis on societal schemas within the therapy milieu as a tool to help families see how societal inequality can affect the problems faced in family life. © 2016 American Association for Marriage and Family Therapy.