Aerobic and anaerobic metabolism for the zebrafish, Danio rerio, reared under normoxic and hypoxic conditions and exposed to acute hypoxia during development Metabolismo aeróbico e anaeróbico do paulistinha Danio rerio, mantidos sob normóxia e hipóxia moderada e expostos a hipóxia aguda durante diferentes estágios de desenvolvimento

Directory of Open Access Journals (Sweden)

WR Barrionuevo

2010-05-01

Full Text Available In order to verify the influence of chronic and acute ambient oxygen levels from egg to adult stage of the zebrafish, in vivo oxygen consumption (MO2, critical tensions of oxygen (Pcrit, heart rate (fH and total body lactate concentration (Lc were determined for Danio rerio (Hamilton, 1822 raised at 28 °C under normoxic (7.5 mgO2.L-1 or 80 mm.Hg-1 and hypoxic conditions (4.3 mgO2.L-1 and exposed to acute hypoxia during different developmental stages. Our findings confirmed that very early stages do not respond effectively to ambient acute hypoxia. However, after the stage corresponding to the age of 30 days, D. rerio was able to respond to acute hypoxia through effective physiological mechanisms involving aerobic and anaerobic metabolism. Such responses were more efficient for the fishes reared under hypoxia which showed that D. rerio survival capability increased during acclimation to mild hypoxia. Measurements of body mass and length showed that moderate hypoxia did not affect growth significantly until the fish reached the stage of 60 days. Moreover, a growth delay was verified for the hypoxic-reared animals. Also, the D. rerio eggs-to-larvae survival varied from 87.7 to 62.4% in animals reared under normoxia and mild hypoxia, respectively. However, the surviving animals raised under moderated hypoxia showed a better aptitude to regulate aerobic and anaerobic capacities when exposed to acute hypoxia.A influência de diferentes níveis de oxigênio no desenvolvimento (ovos a adulto do peixe paulistinha Danio rerio (Hamilton, 1822 foi verificada por meio de medidas experimentais de consumo de oxigênio (MO2, tensões críticas de oxigênio (Pcrit, taxa de batimentos cardíacos (fH e concentração total de lactato nos tecidos (Lc, para os animais mantidos a 28 ºC sob níveis normóxicos de oxigênio (7.5 mgO2.L-1 ou 80 mmHg e hipóxicos (4.3 mgO2.L-1 e submetidos a hipóxia ambiental aguda, em diferentes estágios de desenvolvimento. Os

Gradiente radial de [Mg/Fe] em duas galáxias elípticas

Science.gov (United States)

Milone, A.; Capelato, H.

2003-08-01

Basicamente, são propostos dois cenários de evolução quí mio-dinâmico para os sistemas esferoidais: (i) o hierárquico através da fusão e/ou acresção de sub-sistemas com ou sem surtos de formação estelar, e (ii) o colapso monolí tico dissipativo com formação estelar interrompida por um vento galáctico. Ambos, dentro de certos limites, conseguem explicar os gradientes internos de metalicidade estelar presentes nas galáxias elí pticas bem como a relação observada entre a metalicidade central e a massa (Mg20 vs. log sv0). No entanto, nenhum prevê uma variação interna para a razão de abundâncias Mg/Fe que indiretamente define a escala temporal da formação estelar. Empregamos a espectroscopia óptica de fenda longa com a finalidade de recuperar as histórias de formação estelar, de enriquecimento quí mico e da dinâmica dentro de determinadas regiões das galáxias. Os espectros de média resolução (FWHM = 7,1 Å) e escala angular de 1,092 arcsec/pixel foram coletados com o telescópio 1,60m do OPD/LNA. Comparamos nossas medidas de linhas de absorção com resultados espectrofotométricos de modelos de populações estelares simples - mais especificamente os í ndices do Sistema Lick como Mg2, Mg b, e Hb - a fim de se investigar as variações internas de [Fe/H], [Mg/Fe] e idade. Para duas galáxias elí pticas, NGC 1052 e NGC 7796, pertencentes a ambientes de baixa densidade, encontramos uma variação radial da razão Mg/Fe decrescente do centro para fora em regiões de 0,6 e 1 raio efetivo respectivamente. Discutimos alguns cenários de enriquecimento quí mico para estas duas galáxias.

Spatial chaos of Wang tiles with two symbols

Science.gov (United States)

Chen, Jin-Yu; Chen, Yu-Jie; Hu, Wen-Guei; Lin, Song-Sun

2016-02-01

This investigation completely classifies the spatial chaos problem in plane edge coloring (Wang tiles) with two symbols. For a set of Wang tiles B , spatial chaos occurs when the spatial entropy h ( B ) is positive. B is called a minimal cycle generator if P ( B ) ≠ 0̸ and P ( B ' ) = 0̸ whenever B ' ⫋ B , where P ( B ) is the set of all periodic patterns on ℤ2 generated by B . Given a set of Wang tiles B , write B = C 1 ∪ C 2 ∪ ⋯ ∪ C k ∪ N , where Cj, 1 ≤ j ≤ k, are minimal cycle generators and B contains no minimal cycle generator except those contained in C1∪C2∪⋯∪Ck. Then, the positivity of spatial entropy h ( B ) is completely determined by C1∪C2∪⋯∪Ck. Furthermore, there are 39 equivalence classes of marginal positive-entropy sets of Wang tiles and 18 equivalence classes of saturated zero-entropy sets of Wang tiles. For a set of Wang tiles B , h ( B ) is positive if and only if B contains a MPE set, and h ( B ) is zero if and only if B is a subset of a SZE set.

Department of Zoology and Environmental B

African Journals Online (AJOL)

USER

2017-04-07

Apr 7, 2017 ... impacts on the water quality have directly or indirectly affected the ecological, domestic and other ... to have reliable information on the quality of water for effective management (Wang et al., 2007). For ..... Cambridge, UK. 466pp ... Wang, X., Lu, Y., Han, J., He, G. and ... Zhai, X., Xia, J. and Zhang, Y. (2014).

Bulletin of Materials Science | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Bulletin of Materials Science. F Wang. Articles written in Bulletin of Materials Science. Volume 34 Issue 5 August 2011 pp 1033-1037. Synthesis of Mn-doped CeO2 nanorods and their application as humidity sensors · C H Hu C H Xia F Wang M Zhou P F Yin X Y Han · More Details Abstract Fulltext PDF.

Bulb turbine operating at medium head: XIA JIANG case study

Science.gov (United States)

Loiseau, F.; Desrats, C.; Petit, P.; Liu, J.

2012-11-01

With lots of references for 4-blade bulb turbines, such as these of Wu Jin Xia (4 units - 36.1 MW per unit - 9.2 m rated head), Chang Zhou (15 units - 46.7 MW per unit - 9.5 m rated head) and Tong Wan (4 units - 46.2 MW per unit - 11 m rated head), ALSTOM Power Hydro is one of the major suppliers of bulb turbines operating under medium head for the Chinese market. ALSTOM Power Hydro has been awarded in November 2010 a contract by Jiang Xi Province Xia Jiang Water Control Project Headquarters to equip Xia Jiang's new hydropower plant. The power dam is located on the Gan Jiang river, at about 160 km away from Nan Chang town in South Eastern China. The supply will consist in 5 bulb units including the furniture of both the turbine and its generator, for a total capacity of 200 MW, under a rated net head of 8.6 m. The prototype turbine is a 7.8 m diameter runner, rotating at 71.4 rpm speed. For this project, ALSTOM has proposed a fully new design of 4-blade bulb runner. This paper outlines the main steps of the hydraulic development. First of all, a fine tuning of the blade geometry was performed to enhance the runner behaviour at high loads and low heads, so that to fulfill the demanding requirements of efficiencies and maximum output. The challenge was also to keep an excellent cavitation behaviour, especially at the outer blade diameter in order to avoid cavitation erosion on the prototype. The shape of the blade was optimized by using the latest tools in computational fluid dynamics. Steady state simulations of the distributor and the runner were performed, in order to simulate more accurately the pressure fields on the blade and the velocity distribution at the outlet of the runner. Moreover, draft tube computations have been performed close to the design point and at higher loads. Then, a model fully homologous with the prototype was manufactured and tested at ALSTOM's laboratory in Grenoble (France). The model test results confirmed the predicted ones: the

The Rubber Band Revisited: Wang-Landau Simulation

OpenAIRE

Ferreira, Lucas S.; Caparica, Alvaro A.; Neto, Minos A.; Galiceanu, Mircea D.

2012-01-01

In this work we apply Wang-Landau simulations to a simple model which has exact solutions both in the microcanonical and canonical formalisms. The simulations were carried out by using an updated version of the Wang-Landau sampling. We consider a homopolymer chain consisting of $N$ monomers units which may assume any configuration on the two-dimensional lattice. By imposing constraints to the moves of the polymers we obtain three different models. Our results show that updating the density of...

Bulb turbine operating at medium head: XIA JIANG case study

International Nuclear Information System (INIS)

Loiseau, F; Desrats, C; Petit, P; Liu, J

2012-01-01

With lots of references for 4-blade bulb turbines, such as these of Wu Jin Xia (4 units – 36.1 MW per unit – 9.2 m rated head), Chang Zhou (15 units – 46.7 MW per unit – 9.5 m rated head) and Tong Wan (4 units – 46.2 MW per unit – 11 m rated head), ALSTOM Power Hydro is one of the major suppliers of bulb turbines operating under medium head for the Chinese market. ALSTOM Power Hydro has been awarded in November 2010 a contract by Jiang Xi Province Xia Jiang Water Control Project Headquarters to equip Xia Jiang's new hydropower plant. The power dam is located on the Gan Jiang river, at about 160 km away from Nan Chang town in South Eastern China. The supply will consist in 5 bulb units including the furniture of both the turbine and its generator, for a total capacity of 200 MW, under a rated net head of 8.6 m. The prototype turbine is a 7.8 m diameter runner, rotating at 71.4 rpm speed. For this project, ALSTOM has proposed a fully new design of 4-blade bulb runner. This paper outlines the main steps of the hydraulic development. First of all, a fine tuning of the blade geometry was performed to enhance the runner behaviour at high loads and low heads, so that to fulfill the demanding requirements of efficiencies and maximum output. The challenge was also to keep an excellent cavitation behaviour, especially at the outer blade diameter in order to avoid cavitation erosion on the prototype. The shape of the blade was optimized by using the latest tools in computational fluid dynamics. Steady state simulations of the distributor and the runner were performed, in order to simulate more accurately the pressure fields on the blade and the velocity distribution at the outlet of the runner. Moreover, draft tube computations have been performed close to the design point and at higher loads. Then, a model fully homologous with the prototype was manufactured and tested at ALSTOM's laboratory in Grenoble (France). The model test results confirmed the predicted

Editorial: Which Wei Wang?

International Nuclear Information System (INIS)

Sprouse, Gene D.

2007-01-01

The APS journals receive manuscripts from scientists all over the world. For authors whose names cannot be expressed in Latin characters, their names in the byline must be transliterated, a process that is not necessarily bidirectionally unique. For example, the eight Chinese names all transliterate as Wei Wang. To remove some of the ambiguity arising from this unfortunate degeneracy of names, APS will allow some authors the option to include their names in their own language in parentheses after the transliterated name, such as Wei Wang. The option to present names in the article byline in this manner is an experiment initially offered to Chinese, Japanese, and Korean authors, whose names can be expressed in Unicode characters. An example of a Japanese name is Tadanori Minamisono and a Korean name is Chang Kee Jung. In the English text the given name precedes the family name, while the reverse is true for the characters. As we gain experience, we may be able to broaden this offer to other languages. Authors who wish to try this option will need to prepare their manuscripts by following the special instructions at http://authors.aps.org/names.html

Wang Guowei's Application of Kant

Directory of Open Access Journals (Sweden)

JINLI HE

2015-01-01

Full Text Available Wang Guowei (1887-1927 was a late Qing scholar who assumed a pioneer role in introducing Western philosophy and is regarded as the founder of Chinese ideas about philosophical and literary-aesthetic modernity. His introduction and interpretation not only has been inspiring later scholars to be interested in European philosophy but also being a “showcase” of the “localness” of a cultural interpretation. This paper focuses on Kant’s influence on Wang Guowei, especially Wang’s use of Kant’s epistemological, ethical and aesthetic theories to reconstruct the important Chinese philosophical conceptions, such as, 'xing'性, 'li'理, 'ming'命, 'ya'雅 and what he called as Confucius’ 'meiyuzhuyi'美育主義(aesthetic educational-ism and aims to achieve a better grasp of the continuity and revolution that accompany the emergence of Chinese modernity as well as a better understanding of comparative culture (philosophy in its “primitive” phase.

Evolução química em galáxias compactas azuis (BCGs)

Science.gov (United States)

Lanfranchi, G. A.; Matteucci, F.

2003-08-01

Neste trabalho, a formação estelar e evolução quí mica em galáxias Compactas Azuis (Blue Compact Galaxies - BCGs) foram estudadas através da comparação de previsões de modelos de evolução quí mica a várias razões de abundância quí mica observadas nestas galáxias. Modelos detalhados com recentes dados de nucleossí ntese e que levam em consideração o papel desempenahdo por supernovas de ambos os tipos (II e Ia) na evolução galáctica foram desenvolvidos para as BCGs permitindo seguir a evolução de vários elementos quí micos (H, D, He, C, N, O, Mg, Si, S, Ca, e Fe). O modelo é caracterizado pelas prescrições adotadas para a formação estelar, a qual ocorre em vários surtos de atividade separados por longos perí odos quiescentes. Após ajustar os melhores modelos aos dados observacionais, as previsões destes modelos foram comparadas também a razões de abundância observadas em sistemas Damped Lyman alpha (DLAs) e a origem do N (primária ou secundária) foi discutida. Alguns dos resultados obtidos são: i) as razões de abundância observadas nas BCGs são reproduzidas por modelos com 2 a 7 surtos de formação estelar com eficiência entre n = 0.2-0.9 Gano-1; ii) os baixos valores de N/O observados nestas galáxias são um resultado natural de uma formação estelar em surtos; iii) os modelos para BCGs podem reproduzir os dados dos DLAs, iv) uma quantidade "baixa" de N primário produzido em estrelas de alta massa pode ser uma explicação para os baixos valores de [N/a] observados em DLAs.

New Wang-Landau approach to obtain phase diagrams for multicomponent alloys

Science.gov (United States)

Takeuchi, Kazuhito; Tanaka, Ryohei; Yuge, Koretaka

2017-10-01

We develop an approach to apply the Wang-Landau algorithm to multicomponent alloys in a semi-grand-canonical ensemble. Although the Wang-Landau algorithm has great advantages over conventional sampling methods, there are few applications to alloys. This is because calculating compositions in a semi-grand-canonical ensemble via the Wang-Landau algorithm requires a multidimensional density of states in terms of total energy and compositions, and constructing it is difficult from the viewpoints of both implementation and computational cost. In this study, we develop a simple approach to calculate the alloy phase diagram based on the Wang-Landau algorithm, and show that a number of one-dimensional densities of states could lead to compositions in a semi-grand-canonical ensemble as a multidimensional density of states could. Finally, we apply the present method to Cu-Au and Pd-Rh alloys and confirm that the present method successfully describes the phase diagram with high efficiency, validity, and accuracy.

Dr. Yu Wang, Director, Natural Science Division, National Science Council, Taiwan

CERN Document Server

Patrice Loïez

2001-01-01

Photo 01: L. to r.: Dr. Philippe Bloch, CERN CMS ECAL Deputy Project Manager, Dr. Yu Wang, Dr. Etiennette Auffray, CERN, responsible of the CERN ECAL Regional Centre. Photo 02: L. to r.: Dr. Yu Wang, Dr. Philippe Bloch, Dr. Apollo GO, National Central University, Taiwan, Dr. Etiennette Auffray.

African Journal of Biotechnology - Vol 10, No 35 (2011)

African Journals Online (AJOL)

Interspecific hybridization between Mauremys reevesii and Mauremys sinensis: Evidence from morphology and DNA sequence data · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. X Xia, L Wang, L Nie, Z Huang, Y Jiang, W Jing, L Liu, 6716-6724 ...

The XIA's No.1 Sleeping Prescription for the Treatment of Insomnia of the Deficiency Type:A Clinical Observation of 60 Cases

Institute of Scientific and Technical Information of China (English)

XIA Chao-yun; XIA Cheng-yi; DENG Shi-ping; ZHU Pei-jun

2009-01-01

Objective:To evaluate the therapeutic effects and safety of the XIA's No.1 Sleeping Prescription for the treatment of insomnia of the deficiency type.Methods:120 cases conformed to the diagnostic criteria of the Chinese Classification of Mental Disorders-Version 3 (CCMD-3) and were diagnosed as having insomnia of the deficiency type were divided randomly into a treatment group and a control group, 60 cases in each group.The treatment group was treated with the XIA's No.1 Sleeping Prescription, while the control group was given estazolam (1mg) for 6 weeks.The Athens Insomnia Scale (AIS) was used to evaluate the clinical therapeutic effects, while the treatment emergent symptom scale (TESS) was used to evaluate adverse reactions.Results:The total effective rate of the treatment group (80%) was higher than that of the control group (70%), but with no significant difference (P＞0.05).The effective rate for long-term insomnia was 77.8% in the treatment group and 52.4% in the control group, with a significant difference between the two groups (P＜0.05).The adverse reactions shown in the treatment group were obviously fewer and milder than those in the control group.Conclusion:The XIA's No.1 Sleeping Prescription is effective for insomnia of the deficiency type and with no obvious toxic side effects.

Cryptanalysis of Wang et al.’s lattice-based key exchange protocol

Directory of Open Access Journals (Sweden)

Daya Sagar Gupta

2016-09-01

Full Text Available Wang et al. proposed a new hard problem on lattices which is an extension of the small integer solution (SIS on lattices. This new generated hard problem is named to be bilateral in-homogeneous small integer solution (Bi-ISIS. Using the hardness of Bi-ISIS, Wang et al. proposed a new key exchange protocol, which is based on the lattice-based cryptography. In this paper, we signalize that Wang et al.’s lattice-based key exchange protocol is vulnerable to an attack, namely, man-in-the-middle (MITM attack. Through this attack, Eavesdropper can intercept the authenticated messages and communicate the unauthentic messages among the communicating parties.

Biisofraxidin on Apoptosis of Human Gastric Cancer BGC-823 Cells

African Journals Online (AJOL)

Wu et al. Trop J Pharm Res, October 2015; 14(10): 1803. Tropical Journal of Pharmaceutical Research ... Jian-Tao Wu1,2*, She-Min Lv1, Chun-Hui Lu1, Jun Gong1 and Jian-Bo An3 ..... Zhu AK, Zhou H, Xia JZ, Jin HC, Wang K, Yan J, Zuo JB,.

A distribuição de velocidades na linha de visada em galáxias barradas vistas de face

Science.gov (United States)

Gadotti, D. A.; de Souza, R. E.

2003-08-01

Com o objetivo de realizar um estudo cinemático da componente vertical de barras em galáxias, obtivemos espectros de fenda longa de alta razão S/N ao longo dos eixos maior e menor de 14 galáxias barradas vistas de face, nos telescópios de 1.52m do ESO em La Silla, Chile, e de 2.3m do Steward Observatory em Kitt Peak, Arizona. Estes dados nos permitiram determinar a distribuição de velocidades das estrelas ao longo do eixo vertical das barras e discos destes sistemas, tanto no centro como em pontos que distam cerca de 5 e 20 segundos de arco do núcleo, correspondendo a distâncias de cerca de 0.7 e 2.8 kpc, respectivamente. Desta forma, a variação radial da distribuição de velocidades também pôde ser avaliada. Este tipo de análise tem raros exemplos na literatura por ser caro em termos de tempo de telescópio. Entretanto, é de fácil justificativa, considerando que traz novas informações que podem ser utilizadas para aperfeiçoar modelos teóricos acerca da formação e evolução de galáxias. Um algoritmo por nós desenvolvido foi utilizado para obter as distribuições de velocidades como Gaussianas generalizadas (polinômios de Gauss-Hermite), o que traz um ingrediente a mais neste tipo de estudo que, tradicionalmente, se utiliza de Gaussianas puras, uma hipótese nem sempre razoável. Apresentaremos os resultados deste trabalho, que incluem um diagnóstico para a identificação de barras recém formadas, e testes para o modelo isotérmico de discos. Mostraremos que: (i) a escolha das estrelas padrão em velocidade, e dos parâmetros da Gaussiana, deve ser muito bem justificada já que tem influência significativa nos resultados; (ii) muitas galáxias apresentam uma depressão na dispersão de velocidades na região central, que pode estar associada a um disco interno; e (iii) a dispersão de velocidades é constante ao longo da barra, nos eixos maior e menor, mas cai substancialmente quando se passa da barra para o disco.

Comment on "An Efficient and Stable Hydrodynamic Model With Novel Source Term Discretization Schemes for Overland Flow and Flood Simulations" by Xilin Xia et al.

Science.gov (United States)

Lu, Xinhua; Mao, Bing; Dong, Bingjiang

2018-01-01

Xia et al. (2017) proposed a novel, fully implicit method for the discretization of the bed friction terms for solving the shallow-water equations. The friction terms contain h-7/3 (h denotes water depth), which may be extremely large, introducing machine error when h approaches zero. To address this problem, Xia et al. (2017) introduces auxiliary variables (their equations (37) and (38)) so that h-4/3 rather than h-7/3 is calculated and solves a transformed equation (their equation (39)). The introduced auxiliary variables require extra storage. We implemented an analysis on the magnitude of the friction terms to find that these terms on the whole do not exceed the machine floating-point number precision, and thus we proposed a simple-to-implement technique by splitting h-7/3 into different parts of the friction terms to avoid introducing machine error. This technique does not need extra storage or to solve a transformed equation and thus is more efficient for simulations. We also showed that the surface reconstruction method proposed by Xia et al. (2017) may lead to predictions with spurious wiggles because the reconstructed Riemann states may misrepresent the water gravitational effect.

Evaluating Small Sphere Limit of the Wang-Yau Quasi-Local Energy

Science.gov (United States)

Chen, Po-Ning; Wang, Mu-Tao; Yau, Shing-Tung

2018-01-01

In this article, we study the small sphere limit of the Wang-Yau quasi-local energy defined in Wang and Yau (Phys Rev Lett 102(2):021101, 2009, Commun Math Phys 288(3):919-942, 2009). Given a point p in a spacetime N, we consider a canonical family of surfaces approaching p along its future null cone and evaluate the limit of the Wang-Yau quasi-local energy. The evaluation relies on solving an "optimal embedding equation" whose solutions represent critical points of the quasi-local energy. For a spacetime with matter fields, the scenario is similar to that of the large sphere limit found in Chen et al. (Commun Math Phys 308(3):845-863, 2011). Namely, there is a natural solution which is a local minimum, and the limit of its quasi-local energy recovers the stress-energy tensor at p. For a vacuum spacetime, the quasi-local energy vanishes to higher order and the solution of the optimal embedding equation is more complicated. Nevertheless, we are able to show that there exists a solution that is a local minimum and that the limit of its quasi-local energy is related to the Bel-Robinson tensor. Together with earlier work (Chen et al. 2011), this completes the consistency verification of the Wang-Yau quasi-local energy with all classical limits.

A Systematic Review of the Mysterious Caterpillar Fungus Ophiocordyceps sinensis in Dong-ChongXiaCao (冬蟲夏草 Dōng Chóng Xià Cǎo) and Related Bioactive Ingredients

Science.gov (United States)

Lo, Hui-Chen; Hsieh, Chienyan; Lin, Fang-Yi; Hsu, Tai-Hao

2013-01-01

The caterpillar fungus Ophiocordyceps sinensis (syn.† Cordyceps sinensis), which was originally used in traditional Tibetan and Chinese medicine, is called either “yartsa gunbu” or “DongChongXiaCao (冬蟲夏草 Dōng Chóng Xià Cǎo)” (“winter worm-summer grass”), respectively. The extremely high price of DongChongXiaCao, approximately USD $20,000 to 40,000 per kg, has led to it being regarded as “soft gold” in China. The multi-fungi hypothesis has been proposed for DongChongXiaCao; however, Hirsutella sinensis is the anamorph of O. sinensis. In Chinese, the meaning of “DongChongXiaCao” is different for O. sinensis, Cordyceps spp.,‡ and Cordyceps spƒ. Over 30 bioactivities, such as immunomodulatory, antitumor, anti-inflammatory, and antioxidant activities, have been reported for wild DongChongXiaCao and for the mycelia and culture supernatants of O. sinensis. These bioactivities derive from over 20 bioactive ingredients, mainly extracellular polysaccharides, intracellular polysaccharides, cordycepin, adenosine, mannitol, and sterols. Other bioactive components have been found as well, including two peptides (cordymin and myriocin), melanin, lovastatin, γ-aminobutyric acid, and cordysinins. Recently, the bioactivities of O. sinensis were described, and they include antiarteriosclerosis, antidepression, and antiosteoporosis activities, photoprotection, prevention and treatment of bowel injury, promotion of endurance capacity, and learning-memory improvement. H. sinensis has the ability to accelerate leukocyte recovery, stimulate lymphocyte proliferation, antidiabetes, and improve kidney injury. Starting January 1st, 2013, regulation will dictate that one fungus can only have one name, which will end the system of using separate names for anamorphs. The anamorph name “H. sinensis” has changed by the International Code of Nomenclature for algae, fungi, and plants to O. sinensis. PMID:24716152

A Systematic Review of the Mysterious Caterpillar Fungus Ophiocordyceps sinensis in DongChongXiaCao (冬蟲夏草 Dōng Chóng Xià Cǎo and Related Bioactive Ingredients

Directory of Open Access Journals (Sweden)

Hui-Chen Lo

2013-01-01

Full Text Available The caterpillar fungus Ophiocordyceps sinensis (syn.† Cordyceps sinensis, which was originally used in traditional Tibetan and Chinese medicine, is called either “yartsa gunbu” or “DongChongXiaCao (冬蟲夏草 Dōng Chóng Xià Cǎo” (“winter worm-summer grass”, respectively. The extremely high price of DongChongXiaCao, approximately USD $20,000 to 40,000 per kg, has led to it being regarded as “soft gold” in China. The multi-fungi hypothesis has been proposed for DongChongXiaCao; however, Hirsutella sinensis is the anamorph of O. sinensis. In Chinese, the meaning of “DongChongXiaCao” is different for O. sinensis, Cordyceps spp.,‡ and Cordyceps spƒ. Over 30 bioactivities, such as immunomodulatory, antitumor, anti-inflammatory, and antioxidant activities, have been reported for wild DongChongXiaCao and for the mycelia and culture supernatants of O. sinensis. These bioactivities derive from over 20 bioactive ingredients, mainly extracellular polysaccharides, intracellular polysaccharides, cordycepin, adenosine, mannitol, and sterols. Other bioactive components have been found as well, including two peptides (cordymin and myriocin, melanin, lovastatin, γ-aminobutyric acid, and cordysinins. Recently, the bioactivities of O. sinensis were described, and they include antiarteriosclerosis, antidepression, and antiosteoporosis activities, photoprotection, prevention and treatment of bowel injury, promotion of endurance capacity, and learning-memory improvement. H. sinensis has the ability to accelerate leukocyte recovery, stimulate lymphocyte proliferation, antidiabetes, and improve kidney injury. Starting January 1st, 2013, regulation will dictate that one fungus can only have one name, which will end the system of using separate names for anamorphs. The anamorph name “H. sinensis” has changed by the International Code of Nomenclature for algae, fungi, and plants to O. sinensis.

Estimating the Partition Function Zeros by Using the Wang-Landau Monte Carlo Algorithm

Energy Technology Data Exchange (ETDEWEB)

Kim, Seung-Yeon [Korea National University of Transportation, Chungju (Korea, Republic of)

2017-03-15

The concept of the partition function zeros is one of the most efficient methods for investigating the phase transitions and the critical phenomena in various physical systems. Estimating the partition function zeros requires information on the density of states Ω(E) as a function of the energy E. Currently, the Wang-Landau Monte Carlo algorithm is one of the best methods for calculating Ω(E). The partition function zeros in the complex temperature plane of the Ising model on an L × L square lattice (L = 10 ∼ 80) with a periodic boundary condition have been estimated by using the Wang-Landau Monte Carlo algorithm. The efficiency of the Wang-Landau Monte Carlo algorithm and the accuracies of the partition function zeros have been evaluated for three different, 5%, 10%, and 20%, flatness criteria for the histogram H(E).

Rigorous lower bound on the dynamic critical exponent of some multilevel Swendsen-Wang algorithms

International Nuclear Information System (INIS)

Li, X.; Sokal, A.D.

1991-01-01

We prove the rigorous lower bound z exp ≥α/ν for the dynamic critical exponent of a broad class of multilevel (or ''multigrid'') variants of the Swendsen-Wang algorithm. This proves that such algorithms do suffer from critical slowing down. We conjecture that such algorithms in fact lie in the same dynamic universality class as the stanard Swendsen-Wang algorithm

Symplocaceae

African Journals Online (AJOL)

There are only few reports on the chemical composition of ... However, literature searches have shown no report on ..... Jiang J, Feng Z, Wang Y, Zhang P. New phenolics from the roots of ... Song J, Li N, Xia Y, Gao Z, Zou SF, Kong L, Yao YJ, Jiao. YN, Yan YH ... Han YH, Kee JY, Park J, Kim HL, Jeong MY, Kim DS,. Jeon YD ...

Possible extensions of XIA's digital spectrometer technology to portable and remote monitoring instrumentation

International Nuclear Information System (INIS)

Warburton, W.K.; Darknell, D.A.; Hubbard-Nelson, B.

1998-01-01

The XIA DXP-4C is a 4 channel, CAMAC based, X-ray spectrometer which digitally processes directly digitized preamplifier signals. The DXP-4C was designed for instrumenting multi-detector arrays for synchrotron radiation applications, and optimized for very high count rates at a low cost per detector channel. This produced a very compact and low power (3.4 W/channel) instrument for its count rate and MCA capabilities, which thus provides a strong basis for portable applications. Because all functions are digitally controlled, it can be readily adapted to various user interfaces, including remote access interfaces. Here the authors describe the design and examine approaches to lowering its power to 50 mW/channel. They then consider the issues in applying it to three typical portable or remote spectrometry applications

On a conjecture of Chen-Guo-Wang

OpenAIRE

Ning, Bo; Zheng, Yu

2015-01-01

Towards confirming Sun's conjecture on the strict log-concavity of combinatorial sequence involving the n$th$ Bernoulli number, Chen, Guo and Wang proposed a conjecture about the log-concavity of the function $\\theta(x)=\\sqrt[x]{2\\zeta(x)\\Gamma(x+1)}$ for $x\\in (6,\\infty)$, where $\\zeta(x)$ is the Riemann zeta function and $\\Gamma(x)$ is the Gamma function. In this paper, we first prove this conjecture along the spirit of Zhu's previous work. Second, we extend Chen et al.'s conjecture in the ...

Espectroscopia multi-objeto e imageamento de Abell 586 com GMOS - o estado dinâmico de um aglomerado de galáxias com arcos gravitacionais

Science.gov (United States)

Cypriano, E. S.; Sodré, L., Jr.; Kneib, J.-P.; Campusano, L.

2003-08-01

Nesse trabalho é apresentado um estudo do conteúdo de massa do aglomerado de galáxias A586 (z = 0.171) bem como sua distribuição espacial. Isso foi feito a partir de dados de espectroscopia multi-objeto e imageamento obtidos com o instrumento GMOS acoplado ao telescópio Gemini-Norte. A massa desse aglomerado foi estudada a partir da posição dos seus arcos gravitacionais (lentes fortes), da medida estatística da distorção na forma das galáxias de fundo (lentes fracas) e através da dispersão de velocidades de uma amostra de cerca de 30 galáxias pertencentes ao aglomerado (teorema do virial). Os dois primeiros métodos não dependem do estado dinâmico do aglomerado, enquanto que o terceiro sim. Desse modo, comparando seus resultados pode-se estimar o grau de relaxamento desse sistema. Dados de raios X presentes na literatura também serão incluídos nessa análise. Nossos resultados preliminares a partir das técnicas de lentes fracas, mostram que, supondo que a distribuição de massa desse aglomerado seja a de uma esfera isotérmica, espera-se que ele apresente uma dispersão de velocidades de 1330+/-78 km s-1, em contradicao com medidas similares feitas por Dahle et al. 2002 que encontram valores tão altos quanto 1680 km s-1. Já o estudo dinâmico resultou numa dispersão de velocidades de ~950 km s-1.

A note on Wang et al's attack on Zhang et al's multiparty quantum secret sharing

International Nuclear Information System (INIS)

Gao Gan

2012-01-01

Recently, Wang et al (2008 Phys. Lett. A 373 65) proposed an attack on Zhang et al's (2007 Opt. Commun. 269 418) multiparty quantum secret sharing scheme, in which the first and the last agent are reported to be able to cooperatively eavesdrop on all the secret messages without being detected. In this paper, we show that in Wang et al's attack, on average no more than half the secret messages can be eavesdropped. (paper)

Low Illumination Light (LIL) Solar Cells: Indoor and Monochromatic Light Harvesting

Science.gov (United States)

2015-11-01

zero net energy (ZNE) building, Internet of Things (IoT), and indirect energy conversion isotope battery (IDEC iBAT) systems. Characterizing...have led to rise of the popular phrase, Internet of Things (IoT).3 IoT is, simply, an embedded network of individual nodes that are connected...Francis Group, pp. 88.1–88.10, 2014. 3. Vinel A, Wang L, Yang LT, Feng and Xia., Internet of things . International Journal of Communications Systems

Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212).

Science.gov (United States)

Pinto, Donald J P; Orwat, Michael J; Smith, Leon M; Quan, Mimi L; Lam, Patrick Y S; Rossi, Karen A; Apedo, Atsu; Bozarth, Jeffrey M; Wu, Yiming; Zheng, Joanna J; Xin, Baomin; Toussaint, Nathalie; Stetsko, Paul; Gudmundsson, Olafur; Maxwell, Brad; Crain, Earl J; Wong, Pancras C; Lou, Zhen; Harper, Timothy W; Chacko, Silvi A; Myers, Joseph E; Sheriff, Steven; Zhang, Huiping; Hou, Xiaoping; Mathur, Arvind; Seiffert, Dietmar A; Wexler, Ruth R; Luettgen, Joseph M; Ewing, William R

2017-12-14

Factor XIa (FXIa) is a blood coagulation enzyme that is involved in the amplification of thrombin generation. Mounting evidence suggests that direct inhibition of FXIa can block pathologic thrombus formation while preserving normal hemostasis. Preclinical studies using a variety of approaches to reduce FXIa activity, including direct inhibitors of FXIa, have demonstrated good antithrombotic efficacy without increasing bleeding. On the basis of this potential, we targeted our efforts at identifying potent inhibitors of FXIa with a focus on discovering an acute antithrombotic agent for use in a hospital setting. Herein we describe the discovery of a potent FXIa clinical candidate, 55 (FXIa K i = 0.7 nM), with excellent preclinical efficacy in thrombosis models and aqueous solubility suitable for intravenous administration. BMS-962212 is a reversible, direct, and highly selective small molecule inhibitor of FXIa.

Deterministic integer multiple firing depending on initial state in Wang model

Energy Technology Data Exchange (ETDEWEB)

Xie Yong [Institute of Nonlinear Dynamics, MSSV, Department of Engineering Mechanics, Xi' an Jiaotong University, Xi' an 710049 (China)]. E-mail: yxie@mail.xjtu.edu.cn; Xu Jianxue [Institute of Nonlinear Dynamics, MSSV, Department of Engineering Mechanics, Xi' an Jiaotong University, Xi' an 710049 (China); Jiang Jun [Institute of Nonlinear Dynamics, MSSV, Department of Engineering Mechanics, Xi' an Jiaotong University, Xi' an 710049 (China)

2006-12-15

We investigate numerically dynamical behaviour of the Wang model, which describes the rhythmic activities of thalamic relay neurons. The model neuron exhibits Type I excitability from a global view, but Type II excitability from a local view. There exists a narrow range of bistability, in which a subthreshold oscillation and a suprathreshold firing behaviour coexist. A special firing pattern, integer multiple firing can be found in the certain part of the bistable range. The characteristic feature of such firing pattern is that the histogram of interspike intervals has a multipeaked structure, and the peaks are located at about integer multiples of a basic interspike interval. Since the Wang model is noise-free, the integer multiple firing is a deterministic firing pattern. The existence of bistability leads to the deterministic integer multiple firing depending on the initial state of the model neuron, i.e., the initial values of the state variables.

Deterministic integer multiple firing depending on initial state in Wang model

International Nuclear Information System (INIS)

Xie Yong; Xu Jianxue; Jiang Jun

2006-01-01

We investigate numerically dynamical behaviour of the Wang model, which describes the rhythmic activities of thalamic relay neurons. The model neuron exhibits Type I excitability from a global view, but Type II excitability from a local view. There exists a narrow range of bistability, in which a subthreshold oscillation and a suprathreshold firing behaviour coexist. A special firing pattern, integer multiple firing can be found in the certain part of the bistable range. The characteristic feature of such firing pattern is that the histogram of interspike intervals has a multipeaked structure, and the peaks are located at about integer multiples of a basic interspike interval. Since the Wang model is noise-free, the integer multiple firing is a deterministic firing pattern. The existence of bistability leads to the deterministic integer multiple firing depending on the initial state of the model neuron, i.e., the initial values of the state variables

The ABCs of Chinese Pop: Wang Leehom and the Marketing of a Global Chinese Celebrity

Directory of Open Access Journals (Sweden)

Grace Wang

2012-06-01

Full Text Available How did singer Wang Leehom, a Chinese American raised in the suburbs of New York, end up becoming one of the industry heavyweights of Mandopop (Mandarin-language pop music? This essay uses Wang as a case study to investigate how discourses of race, market, and belonging are reworked in global contexts. Drawing on Sau-ling Wong’s theoretical insights on transnational processes of race, citizenship, and belonging, it argues that Wang capitalizes on a fluid dynamic of sameness and difference to appeal to a heterogeneous Chinese-speaking audience that stretches across China to Taiwan, Hong Kong, Southeast Asia, and the greater Chinese diaspora. Through an examination of the racial and national contexts that frame Wang’s participation in Mandopop, this essay analyzes the particular calibrations of Chineseness that emerge from the singer’s music and public image and the imperfect translation of identities such as Chinese American, Chinese diasporic, and Chinese across diverse linguistic and national communities.

THE APPLICATION OF SURVEY IN ER WANG TEMPLE RESTITUTING

Directory of Open Access Journals (Sweden)

W. Shuai

2013-07-01

Full Text Available Er Wang Temple, in World Heritage Site "Dujiang Weirs and Qingchengshan Mountai", was severely destroyed in Wenchuan earthquake of May 2008. There are several problems at different level in every building, such as structural distortion, foundation displacement, wall fracture, roof damage, etc. The stage was completely collapsed in the earthquake. Tableland the stage situated had a huge crack and slope collapse. This article is for the stage renovation. The survey of damage in earthquake is the basis of Er Wang Temple restituting. Survey including field survey after the earthquake and the measurement and investigation for the remained construction member of the main wood structure. For field survey, the basis of pillars which had not have significantly affects in earthquake could be seem as the reference points for measurement. The investigation of remained main wood construction member, especially the size of the key structures and site and manufacture method of the joints, is the important basis for recovery stage. Our team did our utmost to restore the original appearance of stage in design, materials and craft by various tools, which include measured drawings in different times, old images collection, fine measuring by 3D laser scan, measurement of leftover pieces, logical inference.

[Professor WANG Fuchun's experience in the acupoint selection of clinical treatment with acupuncture and moxibustion].

Science.gov (United States)

Jiang, Hailin; Liu, Chengyu; Ha, Lijuan; Li, Tie

2017-11-12

Professor WANG Fuchun 's experience in the acupoint selection of clinical treatment with acupuncture and moxibustion was summarized. The main acupoints are selected by focusing on the chief symptoms of disease, the supplementary points are selected by differentiating the disorders. The acupoints are modified in terms of the changes of sickness. The effective acupoints are selected flexibly in accordance with the specific effects of points. The summary on the acupoint selection reflects professor WANG Fuchun 's academic thoughts and clinical experience and effectively instructs the clinical practice of acupuncture and moxibustion.

Hydrothermal synthesis of porous Co(OH)2 nanoflake array film and ...

Indian Academy of Sciences (India)

sented discharge current and M (mg), V (V) and t (s) designate mass of ..... Chang Z R, Li H J, Tang H W, Yuan X Z and Wang H J 2009 Int. J. Hydrogen. Energy ... Interfaces 3 99. Kong L B, Liu M C, Lang J W, Liu M, Luo Y C and Kang L 2011 ... Yuan Y F, Xia X H, Wu J B, Yang J L, Chen Y B and Guo S Y 2011. Electrochim.

[Experience summary of professor WANG Fuchun's "Zhenjing Anshen" acupuncture method for insomnia].

Science.gov (United States)

Li, Tie; Ha, Lijuan; Cao, Fang; Zhi, Mujun; Wang, Fuchun

2015-11-01

The experience of "Zhenjing Anshen" acupuncture method originally created by professor WANG Fuchun for treatment of insomnia was introduced in this paper. From aspects of insomnia pathogenesis, theoretical foundation, characteristics of acupoint selection, needing methods, needing time, etc., the experience of Professor WANG Fuchun for treatment of insomnia was explained. The "Zhenjing Anshen" acupuncture method proposed, for the first time, "new three layers" method of acupoint selection, including Sishencong (EX-HN 1), Shenmen (HT 7), Sanyinjiao (SP 6). This method presents the principles of acupoint selection along meridian, acupoint selection based on essence-qi-spirit, harmony of yin and yang. The acupuncture manipulation is emphasized, and treating time (the period of the day from 3 pm to 5 pm) is focused on; acupoint selection is simple but essential, and acupoint combination is scientific, which receives notable therapeutic effect in clinic.

A power law of order 1/4 for critical mean field Swendsen-Wang dynamics

CERN Document Server

Long, Yun; Ning, Weiyang; Peres, Yuval

2014-01-01

The Swendsen-Wang dynamics is a Markov chain widely used by physicists to sample from the Boltzmann-Gibbs distribution of the Ising model. Cooper, Dyer, Frieze and Rue proved that on the complete graph K_n the mixing time of the chain is at most O(\\sqrt{n}) for all non-critical temperatures. In this paper the authors show that the mixing time is \\Theta(1) in high temperatures, \\Theta(\\log n) in low temperatures and \\Theta(n^{1/4}) at criticality. They also provide an upper bound of O(\\log n) for Swendsen-Wang dynamics for the q-state ferromagnetic Potts model on any tree of n vertices.

[Professor WANG Yin's academic thoughts and clinical application of acupuncture for spleen-sto-mach care].

Science.gov (United States)

Niu, Hua; Cao, Haibo; Wang, Yin

Professor WANG Yin 's academic thoughts and clinical application for difficult and miscellaneous di-seases, especially acupuncture for spleen-stomach care, are introduced. Based on TCM basic theory and "ten needles for elderly" by WANG Yueting , Professor WANG Yin proposes the acupuncture for spleen-stomach care. In this method, three-element acupoint selection is applied; the conception vessel, spleen meridian of foot taiyin and stomach meridian of foot yangming were selected. The deep and penetration acupuncture with 0.4 mm×100 mm elongated needles is used at Zhongwan (CV 12), Qihai (CV 6) and Zigong (EX-CA 1), and the mild reinforcing-reducing method is used at remaining acupoints. According to the severity of diseases, fire acupuncture combined with blood-letting cupping is applied at Tianshu (ST 25), Xuehai (SP 10) and Yinlingquan (SP 9); gene-rally, two acupoints are selected and 1 to 3 mL blood-letting is appropriate. The modification based on this me-thod can be applied for various difficult and miscellaneous diseases, leading to superior efficacy.

From Wang-Chen System with Only One Stable Equilibrium to a New Chaotic System Without Equilibrium

Science.gov (United States)

Pham, Viet-Thanh; Wang, Xiong; Jafari, Sajad; Volos, Christos; Kapitaniak, Tomasz

2017-06-01

Wang-Chen system with only one stable equilibrium as well as the coexistence of hidden attractors has attracted increasing interest due to its striking features. In this work, the effect of state feedback on Wang-Chen system is investigated by introducing a further state variable. It is worth noting that a new chaotic system without equilibrium is obtained. We believe that the system is an interesting example to illustrate the conversion of hidden attractors with one stable equilibrium to hidden attractors without equilibrium.

[Professor WANG Linpeng's experience of acupuncture for migraine based on different stages and types].

Science.gov (United States)

Wang, Shaosong

2016-07-12

By using the methods of experience summary and case report, professor WANG Linpeng 's clinical experience of acupuncture for migraine was summarized.Professor WANG proposed the different acupuncture plans should be established according to the active stage and remission stage of migraine; in the active stage acupuncture should be applied at gallbladder meridian with penetration needling technique to reinforce the stimulation intensity; in the remission stage the aim was to regulate zang-fu and back- shu points should be emphasized.In addition, attention should be paid on acupuncture technique and preventive treatment.For menstruation-type and psychological disorder-type migraine, different acupuncture plans should be adopted and regulating meridian and spirit was essential in the treatment.

Yue Joseph Wang named Grant A. Dove Professor of Electrical and Computer Engineering

OpenAIRE

Owczarski, Mark

2009-01-01

Yue Joseph Wang, professor of electrical and computer engineering in the College of Engineering at Virginia Tech, has been named the Grant A. Dove Professor of Electrical and Computer Engineering by the Virginia Tech Board of Visitors.

Multiple Walkers in the Wang-Landau Algorithm

Energy Technology Data Exchange (ETDEWEB)

Brown, G

2005-12-28

The mean cost for converging an estimated density of states using the Wang-Landau algorithm is measured for the Ising and Heisenberg models. The cost increases in a power-law fashion with the number of spins, with an exponent near 3 for one-dimensional models, and closer to 2.4 for two-dimensional models. The effect of multiple, simultaneous walkers on the cost is also measured. For the one-dimensional Ising model the cost can increase with the number of walkers for large systems. For both the Ising and Heisenberg models in two-dimensions, no adverse impact on the cost is observed. Thus multiple walkers is a strategy that should scale well in a parallel computing environment for many models of magnetic materials.

Dynamics analysis of fractional order Yu-Wang system

Science.gov (United States)

Bhalekar, Sachin

2013-10-01

Fractional order version of a dynamical system introduced by Yu and Wang (Engineering, Technology & Applied Science Research, 2, (2012) 209-215) is discussed in this article. The basic dynamical properties of the system are studied. Minimum effective dimension 0.942329 for the existence of chaos in the proposed system is obtained using the analytical result. For chaos detection, we have calculated maximum Lyapunov exponents for various values of fractional order. Feedback control method is then used to control chaos in the system. Further, the system is synchronized with itself and with fractional order financial system using active control technique. Modified Adams-Bashforth-Moulton algorithm is used for numerical simulations.

Classificação geométrica de galáxias bianeladas através do metódo CART (Classification And Regression Trees)

Science.gov (United States)

Ormeño, M. I.; Faúndez-Abans, M.; Cavada, G.

2003-08-01

A importância deste trabalho deve-se à seleção de objetos ainda não tratados particularmente como uma família e ao emprego de procedimento estatístico robusto que não precisa de pressupostos ou condições de contorno. Contribui, assim, ao melhor entendimento do cenário das Galáxias Aneladas do diagrama de Hubble via classificação e estudo de subclasses. Selecionaram-se 100 galáxias possuidoras de dois anéis do Catalog of Southern Ringed Galaxies compilado por Ronald Buta, de modo a construir uma amostra completa em termos de conhecimento dos semi-eixos dos anéis interno e externo projetados no plano do céu. Visando uma possível classificação destas galáxias aneladas normais em famílias de acordo com as características geométricas dos anéis, empregou-se primeiramente a Análise de Aglomerados (ferramenta de classificação: medições de semelhança em um espaço bidimensional) para explorar a possível existência de famílias. As variáveis analisadas foram: os diâmetros interiores menores d(I) e maiores D(I), os diâmetros exteriores menores d(E) e maiores D(E), e os ângulos de inclinação dos semi-eixos maiores interiores q(I) e exteriores q(E) dos anéis. Como metodologia de discriminação, empregou-se a construção de Árvores de Classificação. As árvores de classificação constituem um método de discriminação alternativo aos modelos clássicos, tais como a Análise Discriminante e a Regressão Logística, onde uma base de dados é dividida em partições (subgrupos) da árvore por ação de um predictor (variável específica). Os pacotes estatísticos utilizados para o processamento da informação foram: SAS versão 8.0 (Statistical Analisys System) e CART versão 3.6.3. Esta análise estatística sugere a existência de três possíveis famílias de galáxias bianeladas, com base apenas na geometria dos anéis. Como forma exploratória inicial deste resultado, a construção de um diagrama BT (magnitude total) versus o

Possible extensions of XIA's digital spectrometer technology to portable and remote monitoring instrumentation

International Nuclear Information System (INIS)

Warburton, W.K.; Darknell, D.A.; Hubbard, B.

1998-01-01

The XIA DXP-4C, a 4 channel, CAMAC based X-ray spectrometer, is based on digitally processing directly digitized preamplifier signals. Designed for instrumenting multi-detector arrays for synchrotron radiation applications, the DXP-4C was optimized for very high count rates at a low cost per detector channel. These design constraints coincidentally lead to an instrument which is very compact and relatively low power (3.4 W/channel), considering its count rate and MCA capabilities, and which therefore offers interesting possibilities for effective extension to portable applications. Further, because all functions (gain, filter parameters, pileup inspection criteria and internal calibrations) are digitally controlled, the design can be readily adapted to a large variety of user interfaces, including remote access interfaces. Here we present the basics of the design and examine approaches to lowering the power to less than 300 mW/channel while retaining count rate capabilities in excess of 50,000 cps. We then consider the engineering issues associated with portable and remote spectrometry applications, examining in detail the three cases of a lead paint detector, a remote contamination monitor, and a space mission spectrometer. (author)

Desinfestação por atmosfera anóxia: método utilizado pela biblioteca do conjunto das Químicas/USP

Directory of Open Access Journals (Sweden)

Marina Mayumi Yamashita

2013-01-01

Full Text Available Este trabalho descreve como foi realizada a desinfestação, por atmosfera anóxia, nas coleções de livros e periódicos. O objetivo é relatar o tratamento nas obras infestadas. A desinfestação mostrou-se eficiente e eficaz resultando na valorização da preservação do patrimônio bibliográfico da Divisão de Biblioteca e Documentação do Conjunto das Químicas da Universidade de São Paulo e criando uma consciência da importância das medidas preventivas e corretivas.

The Wang-Landau Sampling Algorithm

Science.gov (United States)

Landau, David P.

2003-03-01

Over the past several decades Monte Carlo simulations[1] have evolved into a powerful tool for the study of wide-ranging problems in statistical/condensed matter physics. Standard methods sample the probability distribution for the states of the system, usually in the canonical ensemble, and enormous improvements have been made in performance through the implementation of novel algorithms. Nonetheless, difficulties arise near phase transitions, either due to critical slowing down near 2nd order transitions or to metastability near 1st order transitions, thus limiting the applicability of the method. We shall describe a new and different Monte Carlo approach [2] that uses a random walk in energy space to determine the density of states directly. Once the density of states is estimated, all thermodynamic properties can be calculated at all temperatures. This approach can be extended to multi-dimensional parameter spaces and has already found use in classical models of interacting particles including systems with complex energy landscapes, e.g., spin glasses, protein folding models, etc., as well as for quantum models. 1. A Guide to Monte Carlo Simulations in Statistical Physics, D. P. Landau and K. Binder (Cambridge U. Press, Cambridge, 2000). 2. Fugao Wang and D. P. Landau, Phys. Rev. Lett. 86, 2050 (2001); Phys. Rev. E64, 056101-1 (2001).

An Interview with Shiang-Kwei Wang: Digital Immigrants versus Digital Natives

OpenAIRE

Shaughnessy, Michael F; Kleyn Kennedy, Cynthia Anne

2015-01-01

In the field of instructional technology and educational technology, there has always been a discussion about the “great divide“ between digital immigrants and digital natives. Teachers often express exasperation as to the lack of skills that students often possess, and the general consensus that purports that the pupils of today are technologically literate and that their “learning curve” is vastly superior to those of past generations. In this interview, Dr. Shiang-Wei Wang responds to ques...

New phenomenon in early development of sporelings in Gracilaria asiatica Chang et Xia (Gracilariaceae, Rhodophyta)

Science.gov (United States)

Zhao, Fengjuan; Wang, Aihua; Liu, Jidong; Duan, Delin

2006-12-01

Study on the early development of sporelings from carpospores of Gracilaria asiatica Chang et Xia was conducted indoors under controlled culture conditions. Besides normal development of sporelings, a new developmental phenomenon of filamentous frond was observed. It was composed of one or two rows of cells, and took place from the outmost brim of the basal disc. During the early disc stage of germinated carpospores, one or two filamentous fronds formed on about 10% basal discs. Simultaneously, young fronds began to arch slightly from the centers of single and coalescent discs; lately more filamentous fronds up to 80% appeared on the brims of basal discs. Meanwhile one or more upright fronds protuberated on the basal discs. Generally, filamentous fronds exhibited in self-existence or co-existence forms with normal young sporelings on the same basal disc, and single cell detached from filamentous fronds developed into a new filamentous frond. This new phenomenon exhibited a unique differentiation pathway during the early development of G. asiatica, which would be potential for the application in artificial sporelings nursery.

Wang-Landau Reaction Ensemble Method: Simulation of Weak Polyelectrolytes and General Acid-Base Reactions.

Science.gov (United States)

Landsgesell, Jonas; Holm, Christian; Smiatek, Jens

2017-02-14

We present a novel method for the study of weak polyelectrolytes and general acid-base reactions in molecular dynamics and Monte Carlo simulations. The approach combines the advantages of the reaction ensemble and the Wang-Landau sampling method. Deprotonation and protonation reactions are simulated explicitly with the help of the reaction ensemble method, while the accurate sampling of the corresponding phase space is achieved by the Wang-Landau approach. The combination of both techniques provides a sufficient statistical accuracy such that meaningful estimates for the density of states and the partition sum can be obtained. With regard to these estimates, several thermodynamic observables like the heat capacity or reaction free energies can be calculated. We demonstrate that the computation times for the calculation of titration curves with a high statistical accuracy can be significantly decreased when compared to the original reaction ensemble method. The applicability of our approach is validated by the study of weak polyelectrolytes and their thermodynamic properties.

Becoming an International Scientist in South Korea: Ho Wang Lee’s Research Activity about Epidemic Hemorrhagic Fever

Directory of Open Access Journals (Sweden)

Miyoung SHIN

2017-04-01

Full Text Available In the 1960-70s, South Korea was still in the position of a science latecomer. Although the scientific research environment in South Korea at that time was insufficient, there was a scientist who achieved outcomes that could be recognized internationally while acting in South Korea. He was Ho Wang Lee(1928~ who found Hantann Virus that causes epidemic hemorrhagic fever for the first time in the world. It became a clue to identify causative viruses of hemorrhagic diseases that were scattered here and there throughout the world. In addition, these outcomes put Ho Wang Lee on the global center of research into epidemic hemorrhagic fever. This paper examines how a Korean scientist who was in the periphery of virology could go into the central area of virology. Also this article shows the process through which the virus found by Ho Wang Lee was registered with the international academia and he proceeded with follow-up research based on this progress to reach the level at which he generalized epidemic hemorrhagic fever related studies throughout the world. While he was conducting the studies, experimental methods that he had never experienced encountered him as new difficulties. He tried to solve the new difficulties faced in his changed status through devices of cooperation and connection. Ho Wang Lee’s growth as a researcher can be seen as well as a view of a researcher that grew from a regional level to an international level and could advance from the area of non-mainstream into the mainstream. This analytic tool is meaningful in that it can be another method of examining the growth process of scientists in South Korea or developing countries.

Security analysis of boolean algebra based on Zhang-Wang digital signature scheme

International Nuclear Information System (INIS)

Zheng, Jinbin

2014-01-01

In 2005, Zhang and Wang proposed an improvement signature scheme without using one-way hash function and message redundancy. In this paper, we show that this scheme exits potential safety concerns through the analysis of boolean algebra, such as bitwise exclusive-or, and point out that mapping is not one to one between assembly instructions and machine code actually by means of the analysis of the result of the assembly program segment, and which possibly causes safety problems unknown to the software

Security analysis of boolean algebra based on Zhang-Wang digital signature scheme

Energy Technology Data Exchange (ETDEWEB)

Zheng, Jinbin, E-mail: jbzheng518@163.com [School of Mathematics and Computer Science, Long Yan University, Longyan 364012 (China)

2014-10-06

In 2005, Zhang and Wang proposed an improvement signature scheme without using one-way hash function and message redundancy. In this paper, we show that this scheme exits potential safety concerns through the analysis of boolean algebra, such as bitwise exclusive-or, and point out that mapping is not one to one between assembly instructions and machine code actually by means of the analysis of the result of the assembly program segment, and which possibly causes safety problems unknown to the software.

The Wang-Meng interacting model and the gravitational collapse

International Nuclear Information System (INIS)

Campos, Miguel de

2013-01-01

Full text: Several alternatives have appear in the literature to supply the accelerated process of universal expansion, and the simplest possibility is to consider the inclusion of a cosmological constant. The inclusion can be realized in both sides of the Einstein field equations, furnishing different physical interpretations in accord with the side of the Einstein field equations where the Λ is added. Considering the inclusion of the cosmological constant in the energy momentum tensor, this additional content is generally interpreted as the energy storage on the vacuum state of all fields in the universe. The inclusion of a vacuum component in the universal fluid furnishes an excellent description of the observed universe, but from the theoretical point of view we do not understand why the vacuum energy is so small and of the same order of magnitude of the matter density (cosmological constant problem). Depending on the point of view of the cosmological constant problem, competing approaches were developed considering a dynamical cosmological 'constant'. A more richer possibility is to consider a non-gravitational interaction models, where the interaction can occur between the dark components, the ordinary matter, and they do not evolve separately. The coupling between dark matter and dark energy has been considered in the literature in a three different ways: dark matter decaying to dark energy; dark energy decaying to dark matter; interacting in both directions. Wang and Meng (CQG 22, 283,2005) considered an alternative to the usual approach for the decay law of the Λ-term assuming the effect of the vacuum in the matter expansion rate. The simple manner adopt by the authors unified several current models that includes a vacuum decaying component interacting with matter content. The vacuum component alters the dynamics of the universal expansion process, then is a natural question: how is the influence of the vacuum energy in the gravitational collapse with a

Two alternate proofs of Wang's lune formula for sparse distributed memory and an integral approximation

Science.gov (United States)

Jaeckel, Louis A.

1988-01-01

In Kanerva's Sparse Distributed Memory, writing to and reading from the memory are done in relation to spheres in an n-dimensional binary vector space. Thus it is important to know how many points are in the intersection of two spheres in this space. Two proofs are given of Wang's formula for spheres of unequal radii, and an integral approximation for the intersection in this case.

Estudo da interferência de diferentes dietas nutricionais sobre as ações antiinflamatória e analgésica do Etoricoxib (Arcóxia®)

OpenAIRE

Bianchetti, érica Silva

2006-01-01

O etoricoxib (Arcóxia®) um medicamento novo posicionado para liderar a próxima geração de inibidores seletivos de COX-2 é um coxib de segunda geração potente e de ação rápida sendo motivo atualmente de muitos ensaios clínicos É o mais seletivo de COX-2 de todos os coxibs O objetivo deste estudo foi estudar em modelos in vivo a interferência sobre a atividade antiinflamatória e analgésica do etoricoxib antiinflamatório inibidor seletivo de COX-2 associado a diferentes tipos de dietas nutricion...

Ning Wang, Making a Market Economy; Yan Sun, Corruption and Market in Contemporary China

OpenAIRE

Guiheux, Gilles

2008-01-01

These two works shed light on the conditions under which, in the course of the last 25 years, the command economy has been dismantled and gradually replaced by a market system in China . Yan Sun, a professor of political science, is interested in corruption from a double perspective, both at the macro and the micro level. Ning Wang, a neo-institutionalist economist, asks how, thanks to the reforms, a region (Jingzhou, south of Hubei ) has been converted to pisciculture. Corruption is a crucia...

A series solution of the Falkner-Skan equation using the crocco-wang transformation

Science.gov (United States)

Asaithambi, Asai

A direct series solution for the Falkner-Skan equation is obtained by first transforming the problem using the Crocco-Wang transformation. The transformation converts the third-order problem to a second-order two-point boundary value problem. The method first constructs a series involving the unknown skin-friction coefficient α. Then, α is determined by using the secant method or Newton’s method. The derivative needed for Newton’s method is also computed using a series derived from the transformed differential equation. The method is validated by solving the Falkner-Skan equation for several cases reported previously in the literature.

Chen-Nester-Tung quasi-local energy and Wang-Yau quasi-local mass

Science.gov (United States)

Liu, Jian-Liang; Yu, Chengjie

2017-10-01

In this paper, we show that the Chen-Nester-Tung (CNT) quasi-local energy with 4D isometric matching references is closely related to the Wang-Yau (WY) quasi-local energy. As a particular example, we compute the second variation of the CNT quasi-local energy for axially symmetric Kerr-like spacetimes with axially symmetric embeddings at the obvious critical point (0 , 0) and find that it is a saddle critical point in most of the cases. Also, as a byproduct, we generalize a previous result about the coincidence of the CNT quasi-local energy and Brown-York mass for axially symmetric Kerr-like spacetimes by Tam and the first author Liu and Tam (2016) to general spacetimes.

Influence of yield on in vitro accumulation of aflatoxins in pecan (Carya illinoensis (Wang.) K. Koch) nutmeats.

Science.gov (United States)

McMeans, J L

1983-02-01

Pecans were harvested from trees (Carya illinoensis (Wang.) K. Koch) in November of 1977 through 1979. Kernel meals from high-, medium-, and low-yielding trees were inoculated with a spore suspension of Aspergillus parasiticus and incubated for 7 days at 25 degrees C. Significant differences in aflatoxin accumulation were found among the three substrates, with a direct correlation between high aflatoxin concentration and tree yield.

Influence of yield on in vitro accumulation of aflatoxins in pecan (Carya illinoensis (Wang.) K. Koch) nutmeats.

OpenAIRE

McMeans, J L

1983-01-01

Pecans were harvested from trees (Carya illinoensis (Wang.) K. Koch) in November of 1977 through 1979. Kernel meals from high-, medium-, and low-yielding trees were inoculated with a spore suspension of Aspergillus parasiticus and incubated for 7 days at 25 degrees C. Significant differences in aflatoxin accumulation were found among the three substrates, with a direct correlation between high aflatoxin concentration and tree yield.

Pla d'intervenció individual en la dislèxia i suport a les famílies en el trastorn per dèficit d'atenció i hiperactivitat

OpenAIRE

Jubert Anfrons, Maria Victoria

2013-01-01

Aquest projecte té com a objectiu principal la intervenció en un context d'educació formal, obtenir experiència professional i definir quin és realment el paper del psicopedagog. Consta de tres activitats: un taller per a pares i mares de nens amb TDAH, un pla reeducatiu per a una alumna amb dislèxia i un taller de competència social per a nens amb TEA. El procés d'investigació-acció ha regit tot el procés, el qual es basa en els principis bàsics de la LEC (12/2009) de qualitat i equitat educ...

Answer to Wang and Luo, "Polyploidization increases meiotic recombination frequency in Arabidopsis: a close look at statistical modelling and data analysis"

Directory of Open Access Journals (Sweden)

Pecinka Ales

2012-04-01

Full Text Available Abstract This article is a response to Wang and Luo. See correspondence article http://www.biomedcentral.com/1741-7007/10/30/ [WEBCITE] and the original research article http://www.biomedcentral.com/1741-7007/9/24 [WEBCITE].

Co-expression of the C-terminal domain of Yersinia enterocolitica ...

Indian Academy of Sciences (India)

Home; Journals; Journal of Biosciences; Volume 40; Issue 1. Co-expression of the C-terminal domain of Yersinia enterocolitica invasin enhances the efficacy of classical swine-fever-vectored vaccine based on human adenovirus. Helin Li Pengbo Ning Zhi Lin Wulong Liang Kai Kang Lei He Yanming Zhang. Articles Volume ...

Comments on "Adaptive resolution simulation in equilibrium and beyond" by H. Wang and A. Agarwal

Science.gov (United States)

Klein, R.

2015-09-01

Wang and Agarwal (Eur. Phys. J. Special Topics, this issue, 2015, doi: 10.1140/epjst/e2015-02411-2) discuss variants of Adaptive Resolution Molecular Dynamics Simulations (AdResS), and their applications. Here we comment on their report, addressing scaling properties of the method, artificial forcings implemented to ensure constant density across the full simulation despite changing thermodynamic properties of the simulated media, the possible relation between an AdResS system on the one hand and a phase transition phenomenon on the other, and peculiarities of the SPC/E water model.

Public health impact of disease-behavior dynamics. Comment on "Coupled disease-behavior dynamics on complex networks: A review" by Z. Wang et al.

Science.gov (United States)

Wells, Chad R.; Galvani, Alison P.

2015-12-01

In a loop of dynamic feedback, behavior such as the decision to vaccinate, hand washing, or avoidance influences the progression of the epidemic, yet behavior is driven by the individual's and population's perceived risk of infection during an outbreak. In what we believe will become a seminal paper that stimulates future research as well as an informative teaching aid, Wang et. al. comprehensively review methodological advances that have been used to incorporate human behavior into epidemiological models on the effects of coupling disease transmission and behavior on complex social networks [1]. As illustrated by the recent outbreaks of measles and Middle Eastern Respiratory Syndrome (MERS), here we highlight the importance of coupling behavior and disease transmission that Wang et al. address.

Journal of Biosciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Co-expression of the C-terminal domain of Yersinia enterocolitica invasin enhances the efficacy of classical swine-fever-vectored vaccine based on human adenovirus · Helin Li Pengbo Ning Zhi Lin Wulong Liang Kai Kang Lei He Yanming Zhang · More Details Abstract Fulltext PDF. The use of adenovirus vector-based ...

Browse Title Index

African Journals Online (AJOL)

Items 151 - 200 of 11090 ... C Ko, J Kung, R Mc Donald. Vol 14, No 25 (2015), In vitro microtuberization of Black Zira (Bunium persicum Boiss.) .... Sujing Fu, Hengkang Hu, Qixiang Zhang, Yanming Fang, Zhengxiong Shen, Yuqiong Gao. Vol 7, No 3 (2008), In vitro propagation of miracle berry (Synsepalum dulcificuDaniel) ...

OPTIMIZATION-BASED APPROACH TO TILING OF FINITE AREAS WITH ARBITRARY SETS OF WANG TILES

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Marek Tyburec

2017-11-01

Full Text Available Wang tiles proved to be a convenient tool for the design of aperiodic tilings in computer graphics and in materials engineering. While there are several algorithms for generation of finite-sized tilings, they exploit the specific structure of individual tile sets, which prevents their general usage. In this contribution, we reformulate the NP-complete tiling generation problem as a binary linear program, together with its linear and semidefinite relaxations suitable for the branch and bound method. Finally, we assess the performance of the established formulations on generations of several aperiodic tilings reported in the literature, and conclude that the linear relaxation is better suited for the problem.

Comparison of the Wang and Wachsmuth models for π production with measurements at 12 GeV/c

International Nuclear Information System (INIS)

Fernow, R.C.

1996-01-01

We converted the invariant cross section measurements of Blobel et al. at 12 GeV/c into the form d 2 σ/dΩdp as a function of the LAB total momentum p and p T . We adjusted the parameters of the pion production models of Wang and of Wachsmuth-Hagedorn-Ranft to obtain the best fit to the data. Neither model gave a statistically accurate fit to the data. copyright 1995 American Institute of Physics

A mathematical view for ordinary differential equation models. Comment on ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

Science.gov (United States)

Fu, Guifang

2017-03-01

Qian Wang et al. have written an interesting article to propose a modeling framework named epiGame in this issue of Physics of Life Reviews [1]. The epiGame framework models how the methylation state of paternal and maternal genomes regulates the embryogenesis as an ecological system in which two highly distinct and specialized gametes coordinate through either cooperation or competition, or both, to maximize the fitness of embryos. Qian Wang et al. also provide solid simulation studies and real data analysis to validate the correctness of their epiGame framework. The importance of embryo development and fertility mechanism cannot be overemphasized, hence, I think that the present review by Qian Wang et al. will stand as a useful modeling guide for practicing biologists or researchers in fertility health to quantify how sperms and oocytes interact through epigenetic process to determine embryo development. In addition, it will serve as a source of many important references to work in the reproductive biology field.

H.E. Professor Wang Liheng, Minister of Aviation of the People's Republic of China, President, China Aerospace Science & Technology Corporation

CERN Multimedia

Patrice Loïez

2001-01-01

H. E. Professor Wang Liheng, Minister of Aviation, and President, China Aerospace Science & Technology Corporation, People's Republic of China (2nd from left) with (from left to right) Professor Hans Hofer, Professor Roger Cashmore, Research Director for Collider Programmes, Professor Samuel C. C. Ting, CERN and Professor Lei Gang, Secretary to the Minister, September 2001.

Construção de um catálogo de aglomerados abertos para estudo da dinâmica da estrutura espiral da Galáxia

Science.gov (United States)

Carlos, I. M.; Lépine, J. R. D.

2003-08-01

Os aglomerados abertos são objetos de grande valor para o estudo da dinâmica da Galáxia devido esses objetos terem uma faixa de idade relativamente ampla. O trabalho visa estudar a dinâmica da estrutura espiral da Galáxia principalmente através do uso desses aglomerados, uma vez que o estudo da cinemática desses objetos é fundamental para esse objetivo. Nosso grupo trabalha no sentido de construir uma base de dados de aglomerados abertos contendo coordenadas, distância, idade, movimentos próprios e velocidades radiais e já disponibiliza uma nova versão do catálogo de aglomerados abertos o qual é uma compilação de edições anteriores, principalmente Lynga (1987), Mermilliod (1995) e ESO-B (Lauberts 1982). Nossa amostra possui cerca de 1630 aglomerados, mas nem todos os parâmetros acima citados foram determinados em sua totalidade. Para determinarmos esses parâmetros, derivamos as cores intrínsecas das estrelas membro de cada aglomerado a partir de seus tipos espectrais (busca feita no SIMBAD) obtendo assim o excesso de cor individual. A distribuição dos excessos de cor foi então utilizada para derivarmos o avermelhamento médio para cada aglomerado. De maneira similar, os tipos espectrais foram usados para estimar as magnitudes absolutas, e com as magnitudes absolutas e aparentes determinamos a respectiva distribuição do módulo de distância e finalmente a distância. Para determinar as idades foram confeccionados os diagramas cor-magnitude das estrelas de cada aglomerado onde foram superpostas a Seqüência Principal de Idade Zero (ZAMS). Superpomos a ZAMS de Schmidt-Kaler e isócronas de composição solar. Essas isócronas foram usadas para determinação das idades dos aglomerados. Uma vez que não temos ainda resultados finais, apresentamos então alguns diagramas cor-magnitude os quais foram usados para determinação, principalmente, da distância e idade dos aglomerados.

Macroscopically constrained Wang-Landau method for systems with multiple order parameters and its application to drawing complex phase diagrams

Science.gov (United States)

Chan, C. H.; Brown, G.; Rikvold, P. A.

2017-05-01

A generalized approach to Wang-Landau simulations, macroscopically constrained Wang-Landau, is proposed to simulate the density of states of a system with multiple macroscopic order parameters. The method breaks a multidimensional random-walk process in phase space into many separate, one-dimensional random-walk processes in well-defined subspaces. Each of these random walks is constrained to a different set of values of the macroscopic order parameters. When the multivariable density of states is obtained for one set of values of fieldlike model parameters, the density of states for any other values of these parameters can be obtained by a simple transformation of the total system energy. All thermodynamic quantities of the system can then be rapidly calculated at any point in the phase diagram. We demonstrate how to use the multivariable density of states to draw the phase diagram, as well as order-parameter probability distributions at specific phase points, for a model spin-crossover material: an antiferromagnetic Ising model with ferromagnetic long-range interactions. The fieldlike parameters in this model are an effective magnetic field and the strength of the long-range interaction.

Surface adsorption of lattice HP proteins: Thermodynamics and structural transitions using Wang-Landau sampling

International Nuclear Information System (INIS)

Li Yingwai; Landau, David P; Wüst, Thomas

2012-01-01

Wang-Landau sampling has been applied to investigate the thermodynamics and structural properties of a lattice hydrophobic-polar heteropolymer (the HP protein model) interacting with an attractive substrate. For simplicity, we consider a short HP sequence consisting of only 36 monomers interacting with a substrate which attracts all monomers in the sequence. The conformational “phase transitions” have been identified by a canonical analysis of the specific heat and suitable structural observables. Three major “transitions”, namely, adsorption, hydrophobic core formation and “flattening” of adsorbed structures, are observed. Depending on the surface attractive strength relative to the intra-protein attraction among the H monomers, these processes take place in different sequences upon cooling.

Interview with Xiaoli Wang PhD winner of CACA 2016 Young Investigator Award

Directory of Open Access Journals (Sweden)

Xiaoli Wang

2016-07-01

Full Text Available Xiaoli Wang is currently an R&D Senior Scientist in Agilent’s HPLC instrument R&D group at Agilent Technologies, Waldbronn, Germany. Prior to this, he was an R&D manager in Agilent’s CrossLab Group in the US focusing on development of novel chromatographic columns. He has a B.S. degree in Chemistry from Peking University, Beijing China and a PhD. degree in Analytical Chemistry from the University of Minnesota in 2006. He started his industrial career in the pharmaceutical industry at AstraZeneca for four years before joining Agilent Technologies in 2010. Recently, he won the prestigious 2016 Young Investigator Award from Chinese American Chromatography Association (CACA. This interview was conducted by Roland J.W. Meesters PhD, Editor-in-Chief of Journal of Applied Bioanalysis.

2. Sino-German workshop on fuel cells. Book of abstracts

Energy Technology Data Exchange (ETDEWEB)

NONE

2003-07-01

The CD-ROM contains the content of 13 lectures and 19 proposals for joint projects, which were presented on the second Sino-German Workshop on fuel cells. The topics of the 13 lectures are: Ab-initio calculations of oxygen species on low-index platinum surfaces (Pachenko, M.T.M. Koper, T.E. Shubina, S.J. Mitchell, E. Roduner). Cross-Linked (Composite) Polyaryl Blend Membranes for Membrane Fuel Cells. (J.A. Kerres, A. Ullrich, W. Zhang, M. Hein, V. Gogel, L. Joerissen, Th. Frey, A. Friedrich). Performance and Methanol Permeation of Direct Methanol Fuel Cells: Dependence on Operating Conditions and on Electrode Structure(V. Gogel, Th. Frey, K.A. Friedrich, L. Joerissen, J. Garche, Z. Yongsheng). Experimental Investigation of Flow Bed Configuration Effect on Performance of Liquid Feed Direct Methanol Fuel Cells. (H. Guo, C.F. Ma, M.H. Wang, F. Ye, J. Yu, Y. Wang, C.Y. Wang). Improvement of MEAs for DMFC by a tuned production sequence assisted by mathematical modelling (Lindermeir, G. Rosenthal, U. Kunz, U. Hoffmann). Performance of the self-breathing air DMFC with solution grafted PVDF-g-PSSA membranes (X. Qiu, G. Guo, W. Li, W. Zhu, L. Chen). Modeling the Effects of Methanol Crossover on DMFC (J. Zhang, Y. Wang). The characteristics of 40 kW PEM fuel cell engine for vehicle(M. Hou, P. Ming, H. Zhang). A New and Simple Method for Preparing Biocathode in Biofuel Cells (D. Sun, C. Cai, X. Li, W. Xing, T. Lu). Nonlinear Model Reduction of a Dynamic Two-dimensional Molten Carbonate Fuel Cell Model (M. Mangold, M. Sheng). Recent Advances in Design and Fabrication of Low-Temperature Solid Oxide Fuel Cells (C. Xia, G. Meng). Novel CVD Techniques for Micro- and IT-SOFC Fabrication (G. Meng, H. Song, Q. Dong, D. Peng). Fundamental properties of La{sub 0.6}Sr{sub 0.4}Co{sub 0.8}Fe{sub 0.2}O{sub 3-{delta}} at high temperatures (S. Wang, T.-L. Wen).

Systematic errors due to linear congruential random-number generators with the Swendsen-Wang algorithm: a warning.

Science.gov (United States)

Ossola, Giovanni; Sokal, Alan D

2004-08-01

We show that linear congruential pseudo-random-number generators can cause systematic errors in Monte Carlo simulations using the Swendsen-Wang algorithm, if the lattice size is a multiple of a very large power of 2 and one random number is used per bond. These systematic errors arise from correlations within a single bond-update half-sweep. The errors can be eliminated (or at least radically reduced) by updating the bonds in a random order or in an aperiodic manner. It also helps to use a generator of large modulus (e.g., 60 or more bits).

Zhuyi: From Absence to Bustle? Some Comments on Wang Jianjiang’s Article “The Bustle and the Absence of Zhuyi”

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Aleš Erjavec

2017-09-01

Full Text Available The article is a response to the article published in Filozofski vestnik in 2016 and written by Prof. Wanf Jianjiang who in recent years devoted much of his efforts to the influence of of Western aesthetics and philosophy on Chinese humanities. Thus a notion introduced by Prof. Wang Jianjiang – Zhuyi – became the center of discussion in the papers that are to be found in this volume of AM Journal. Prof. Jianjiang claims that Zhuyi has a similar meaning as Western -ism and argues that Chinese aestheticians and intellectuals in general must develop their own theories (-isms if they want to gain speech and not remain stuck with voice (cf. Jacques Rancière.   Article received: May 3, 2017; Article accepted: May 8, 2017; Published online: September 15, 2017 Original scholarly paper How to cite this article: Erjavec, Aleš. "Zhuyi: From Absence to Bustle? Some Comments on Wang Jianjiang’s Article 'The Bustle and the Absence of Zhuyi'." AM Journal of Art and Media Studies 13 (2017: 111-121. doi: 10.25038/am.v0i13.189

Predictive Control of the Blood Glucose Level in Type I Diabetic Patient Using Delay Differential Equation Wang Model.

Science.gov (United States)

Esna-Ashari, Mojgan; Zekri, Maryam; Askari, Masood; Khalili, Noushin

2017-01-01

Because of increasing risk of diabetes, the measurement along with control of blood sugar has been of great importance in recent decades. In type I diabetes, because of the lack of insulin secretion, the cells cannot absorb glucose leading to low level of glucose. To control blood glucose (BG), the insulin must be injected to the body. This paper proposes a method for BG level regulation in type I diabetes. The control strategy is based on nonlinear model predictive control. The aim of the proposed controller optimized with genetics algorithms is to measure BG level each time and predict it for the next time interval. This merit causes a less amount of control effort, which is the rate of insulin delivered to the patient body. Consequently, this method can decrease the risk of hypoglycemia, a lethal phenomenon in regulating BG level in diabetes caused by a low BG level. Two delay differential equation models, namely Wang model and Enhanced Wang model, are applied as controller model and plant, respectively. The simulation results exhibit an acceptable performance of the proposed controller in meal disturbance rejection and robustness against parameter changes. As a result, if the nutrition of the person decreases instantly, the hypoglycemia will not happen. Furthermore, comparing this method with other works, it was shown that the new method outperforms previous studies.

Transplantation of human umbilical cord blood-derived mononuclear cells induces recovery of motor dysfunction in a rat model of Parkinson's disease

Directory of Open Access Journals (Sweden)

Chen C

2016-04-01

Full Text Available Chao Chen,1,* Jing Duan,1,* Aifang Shen,2,* Wei Wang,1 Hao Song,1 Yanming Liu,1 Xianjie Lu,1 Xiaobing Wang,2 Zhiqing You,1 Zhongchao Han,3,4 Fabin Han1 1Center for Stem Cells and Regenerative Medicine, The Liaocheng People's Hospital, Affiliated Liaocheng Hospital, Taishan Medical University, Shandong, People's Republic of China; 2Department of Gynecology and Obstetrics, The Liaocheng People's Hospital, Affiliated Liaocheng Hospital, Taishan Medical University, Shandong, People's Republic of China; 3The State Key Laboratory of Experimental Hematology, Institute of Hematology and Hospital of Blood Diseases, Chinese Academy of Medical Sciences, Peking Union of Medical College, Tianjin, People's Republic of China; 4National Engineering Research Center of Cell Products, AmCellGene Co. Ltd., TEDA, Tianjin, People's Republic of China*These authors contributed equally to this workAbstract: Human umbilical cord blood-derived mononuclear cells (hUCB-MNCs were reported to have neurorestorative capacity for neurological disorders such as stroke and traumatic brain injury. This study was performed to explore if hUCB-MNC transplantation plays any therapeutic effects for Parkinson's disease (PD in a 6-OHDA-lesioned rat model of PD. hUCB-MNCs were isolated from umbilical cord blood and administered to the striatum of the 6-OHDA-lesioned rats. The apomorphine-induced locomotive turning-overs were measured to evaluate the improvement of motor dysfunctions of the rats after administration of hUCB-MNCs. We observed that transplanted hUCB-MNCs significantly improve the motor deficits of the PD rats and that grafted hUCB-MNCs integrated to the host brains and differentiated to neurons and dopamine neurons in vivo after 16 weeks of transplantation. Our study provided evidence that transplanted hUCB-MNCs play therapeutic effects in a rat PD model by differentiating to neurons and dopamine neurons. Keywords: hUCB-MNCs, Parkinson's disease, transplantation

Hydrogen sulfide, a potential novel drug, attenuates concanavalin A-induced hepatitis

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Cheng P

2014-09-01

Full Text Available Ping Cheng,* Kan Chen,* Yujing Xia, Weiqi Dai, Fan Wang, Miao Shen, Chengfen Wang, Jing Yang, Rong Zhu, Huawei Zhang, Jingjing Li, Yuanyuan Zheng, Junshan Wang, Yan Zhang, Jie Lu, Yingqun Zhou, Chuanyong GuoDepartment of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University of Medicine, Shanghai, People's Republic of China *These authors contributed equally to this work Background: Hydrogen sulfide (H2S is known to exert anti-inflammatory properties. Apoptosis and autophagy play important roles in concanavalin A (Con A-induced acute hepatitis. The purpose of this study was to explore both the effect and mechanism of H2S on Con A-induced acute hepatitis. Methods: BALB/c mice were randomized into sham group, Con A-injection group, and 14 µmol/kg of sodium hydrosulfide (NaHS, an H2S donor pretreatment group. Results: Aspartate aminotransferase, alanine aminotransferase, and pathological damage were significantly ameliorated by NaHS pretreatment. NaHS pretreatment significantly reduced the levels of interleukin-6 and tumor necrosis factor-α compared with those of the Con A group. The expression of Bcl-2, Bax, Beclin-1, and LC3-2, which play important roles in the apoptosis and autophagy pathways, were also clearly affected by NaHS. Furthermore, NaHS affected the p-mTOR and p-AKT. Conclusion: H2S attenuates Con A-induced acute hepatitis by inhibiting apoptosis and autophagy, in part, through activation of the PtdIns3K-AKT1 signaling pathway. Keywords: NaHS, apoptosis, PtdIns3K-AKT, autophagy

Smoke (Paul Auster et Wayne Wang, 1995 : une œuvre à la croisée des arts

Directory of Open Access Journals (Sweden)

Delphine Letort

2011-04-01

Full Text Available The adaptation of the short story entitled “Auggie Wren’s Christmas Story” (1990 gathered the writer Paul Auster and the director Wayne Wang around a film project that allowed them to share their artistic practices in a collaborative work. This paper examines the question that underpins the narrative of the short-story by grappling with the appropriations of the real in other artistic modes. Paul Auster’s first encounter with the cinema points out the convergence between aural writing and cinematic writing, evoked through the double figure of the writer and that of the tale-teller/photographer in both the film and the short story.L’adaptation de la nouvelle « Auggie Wren’s Christmas Story » (1990 réunit l’écrivain Paul Auster et le réalisateur Wayne Wang autour d’un projet qui leur permit de croiser leurs pratiques artistiques dans un travail de collaboration. Cet article prolonge le questionnement artistique qui sous-tend le récit de la nouvelle en interrogeant les modalités de l’appropriation du réel par d’autres arts. La première rencontre entre Paul Auster et le cinéma met en relief les points de convergence entre écriture verbale et écriture cinématographique, évoqués autour de la double figure de l’écrivain et du conteur/photographe dans le film et dans la nouvelle.

¿Cómo podemos usar el móvil para comunicarnos mediante el pensamiento? Entrevista con Yijun Wang

Directory of Open Access Journals (Sweden)

Ángel Correa

2011-01-01

Full Text Available Un equipo de neurocientíficos ha desarrollado una interfaz cerebro ordenador basada en un teléfono móvil. Las personas con movilidad reducida podrían beneficiarse de este innovador sistema en un futuro próximo. En el experimento que aparece en la fotografía de portada, el participante utiliza únicamente su pensamiento para marcar un número de teléfono. Ciencia Cognitiva ha entrevistado al Dr. Yijun Wang, ingeniero biomédico de la Universidad de California en San Diego, que trabaja en este proyecto.

De Hemingway au chinois classique : le travail de la langue de l’écrivain taïwanais Wang Wen-hsing

Directory of Open Access Journals (Sweden)

Sandrine Marchand

2014-04-01

Full Text Available Dans les années 1970, l’« occidentalisation » de Wang Wen-hsing lui attire les foudres de la critique. On lui reproche, entre autres choses, de mal écrire, d’être incompréhensible et d’écrire dans une langue occidentalisée. Lui-même semble prendre pour modèle son professeur de français, dont le niveau de chinois classique était très élevé. Entre chinois classique, moderne, dialecte de sa région natale (très proche du dialecte de Taïwan, anglais, et français idéalisé, Wang Wen-hsing invente sa propre langue. Dans les manuscrits de son premier roman, il recourt au syllabaire que les enfants utilisent en cours d’apprentissage de la langue chinoise pour remplacer les caractères d’écriture, syllabaire qui disparaît ensuite à la publication. Que nous apprend l’utilisation de ce syllabaire sur le travail créatif de l’auteur ?Wang Wen-hsing est un auteur qui, entre extrême précision et violence, consacre sa vie et toute son énergie au travail de la langue. Quelle langue tente-t-il d’approcher : le chinois normatif des temps anciens, la langue américaine de Hemingway, ou un mélange des deux ?Multilingue à l’intérieur de la langue chinoise moderne, elle-même langue encore proche du chinois classique, abandonné seulement au début du xxe siècle, l’écriture romanesque de Wang Wen-hsing, qui a pour critère de valeur le « tong-shun » (clarté et aisance, est le fruit de l’oralité et d’une langue expérimentale. Ce rapport à la langue vient-il de sa situation d’émigration, de son isolement des milieux politiques et intellectuels, comme cela lui a été reproché lorsque justement on l’accusait d’écrire dans une langue incompréhensible pour le lecteur ? Pourquoi ces romans sont-ils jugés incompréhensibles ? En raison du niveau du lecteur moyen ? Pour des raisons géopolitiques, car il est un émigré en position dominante dans l’île ? Parce que la langue chinoise est dans

Tai An's Famous and Aristocratic Official Families in Korean---New Research on Wang Yiwen Family Adherent to the End of Ming Dynasty%流寓韩国的泰安名臣世家--明末遗民王以文族系新考

Institute of Scientific and Technical Information of China (English)

周郢

2016-01-01

韩国历史上著名之“九义士”，乃指明清之际随同朝鲜质子入境的九位明朝士人。其中之王以文，传系明臣王楫孙。王楫为明泰安州人，故里即今岱岳区范镇大王庄。范镇王氏所藏道光钞本《王氏族谱》中，不少内容堪与韩国史料相印证。两者在王楫及其先世的记述基本一致，而王楫之后则存在较大差异。入朝王氏系出于泰安范镇王氏家族洵无疑义，但王以文是否为王楫之孙，仍有进一步查证之余地。%The famous "nine righteous men" in Korean history was the nine scholars who had been ac-companying Korean hostage back to Korean at the end of Ming Dynasty. Wang Yiwen, the grandson of Wang Ji, the Ming minister who was from Da Wang Village of Fan County in Tai An. The book Wangs Pedigree of a Clan formed in Dao Guang of Qing Dynasty contained the same contents with Korean historical materials. Wang Ji and his ancestors' documents are generally the same, and his offspring's are different. So it is con-firmed that Wangs in Korea are from Tai An, but Wang Yiwen's origin should give further investigation.

New contributions to the knowledge of Chinese flea beetle fauna (III): Revision of Meishania Chen & Wang with description of five new species (Coleoptera: Chrysomelidae: Galerucinae)

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The flea beetle genus Meishania Chen & Wang is revised and five new species - M. cangshanensis sp. nov., M. flavipennis sp. nov., M. fulvotigera sp. nov., and M. sichuanica sp. nov. from China and M. bhutanensis sp. nov. from Bhutan - are described. All species of Meishania are illustrated and a key...

Grateloupia ramosa Wang & Luan sp. nov. (Halymeniaceae, Rhodophyta), a new species from China based on morphological evidence and comparative rbcL sequences

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Cao, Cuicui; Liu, Miao; Guo, Shaoru; Zhao, Dan; Luan, Rixiao; Wang, Hongwei

2016-03-01

Grateloupia ramosa Wang & Luan sp. nov. (Halymeniaceae, Rhodophyta) is newly described from Hainan Province, southern China. The organism has the following morphological features: (1) purplish red, cartilaginous and lubricous thalli 5-10 cm in height; (2) compressed percurrent axes bearing abundant branches with opposite arrangement; (3) claw-like apices on top, constricted to 2-4 cm at the base; (4) cortex consisting of 3-6 layers of elliptical or anomalous cells and a medulla covered by compact medullary filaments; (5) reproductive structures distributed throughout the thallus, especially centralized at the bottom of the end portion of the branches; and (6) 4-celled Carpogonial branches and 3-celled auxiliary-cell branches, both of the Grateloupia-type. The morphological diff erences were supported by molecular phylogenetics based on ribulose-1, 5-bisphosphate carboxylase/oxygenase ( rbcL) gene sequence analysis. There was only a 1 bp divergence between specimens collected from Wenchang and Lingshui of Hainan province. The new species was embedded in the large Grateloupia clade of the Halymeniaceae. The pairwise distances between G. ramosa and other species within Grateloupia ranged from 26 to 105 bp, within pairwise distances of 13-111 bp between species of the large genus Grateloupia in Halymeniaceae. Thus, we propose this new species as G. ramosa Wang & Luan sp. nov.

Análise de variáveis fisiológicas de adolescentes com diagnóstico clínico de asma leve intermitente ou leve persistente quando submetidos a hipóxia aguda e teste de esforço máximo Analysis of physiological variables during acute hypoxia and maximal stress test in adolescents clinically diagnosed with mild intermittent or mild persistent asthma

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Martin Maldonado

2011-12-01

Full Text Available OBJETIVO: Analisar variáveis fisiológicas de adolescentes com diagnóstico clínico de asma quando submetidos a teste de hipóxia aguda e de esforço máximo. MÉTODOS: Estudo descritivo transversal composto por 48 adolescentes (12-14 anos, divididos em três grupos: 12 no grupo asma leve intermitente (ALI, 12 no grupo asma leve persistente (ALP e 24 no grupo controle. Todos foram submetidos a teste de hipóxia aguda e a teste de esforço máximo. Características antropométricas foram coletadas, e variáveis funcionais foram determinadas antes e após o teste de esforço máximo. Em condições de hipóxia aguda, foram registrados o tempo de descida e o tempo de recuperação de SpO2 durante repouso. RESULTADOS: Não foram encontradas diferenças significativas nas variáveis antropométricas nem nas variáveis ventilatórias durante o teste de esforço entre os grupos. Foram encontradas diferenças significativas na pressão de oxigênio com 50% de saturação da hemoglobina antes do teste e na PaO2 antes do teste entre os grupos ALP e controle (p = 0,0279 e p = 0,0116, respectivamente, assim como na tensão de extração de oxigênio antes do teste entre os grupos ALI e ALP (p = 0,0419. Não houve diferenças significativas nos tempos de SpO2 em quaisquer das condições estudadas. O consumo de oxigênio e a eficiência da respiração foram semelhantes entre os grupos. O uso de um broncodilatador não trouxe vantagens nos resultados no teste de hipóxia. Não foram encontradas correlações entre o teste de hipóxia e as variáveis fisiológicas. CONCLUSÕES: Nossos achados sugerem que os adolescentes com asma leve persistente têm uma melhor capacidade de adaptação à hipóxia comparado aos com outros tipos de asma.OBJECTIVE: To analyze adolescents clinically diagnosed with asthma, in terms of the physiological changes occurring during acute hypoxia and during a maximal stress test. METHODS: This was a descriptive, cross

NH4HCO3 gas-generating liposomal nanoparticle for photoacoustic imaging in breast cancer

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Xia J

2017-03-01

Full Text Available Jizhu Xia, Gang Feng, Xiaorong Xia, Lan Hao, Zhigang Wang Chongqing Key Laboratory of Ultrasound Molecular Imaging, Department of Ultrasound, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China Abstract: In this study, we have developed a biodegradable nanomaterial for photoacoustic imaging (PAI. Its biodegradation products can be fully eliminated from a living organism. It is a gas-generating nanoparticle of liposome-encapsulating ammonium bicarbonate (NH4HCO3 solution, which is safe, effective, inexpensive, and free of side effects. When lasers irradiate these nanoparticles, NH4HCO3 decomposes to produce CO2, which can absorb much of the light energy under laser irradiation with a specific wavelength, and then expand under heat to generate a thermal acoustic wave. An acoustic detector can detect this wave and show it as a photoacoustic signal on a display screen. The intensity of the photoacoustic signal is enhanced corresponding to an increase in time, concentration, and temperature. During in vivo testing, nanoparticles were injected into tumor-bearing nude mice through the caudal vein, and photoacoustic signals were detected from the tumor, reaching a peak in 4 h, and then gradually disappearing. There was no damage to the skin or subcutaneous tissue from laser radiation. Our developed gas-generating nanomaterial, NH4HCO3 nanomaterial, is feasible, effective, safe, and inexpensive. Therefore, it is a promising material to be used in clinical PAI. Keywords: Photoacoustic tomography, CO2, NH4HCO3, contrast agent, cancer

Effect of magnetic nanoparticles on apoptosis and cell cycle induced by wogonin in Raji cells

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Wang XM

2012-02-01

Full Text Available Lei Wang1,2,*, Haijun Zhang1,2,*, Baoan Chen1,2, Guohua Xia1,2, Shuai Wang1,2, Jian Cheng1,2, Zeye Shao1,2, Chong Gao1,2, Wen Bao1,2, Liang Tian1,2, Yanyan Ren1,2, Peipei Xu1,2, Xiaohui Cai1,2, Ran Liu1,2, Xuemei Wang3 1Department of Hematology and Oncology, Zhongda Hospital, Medical School, 2Faculty of Oncology, Medical School, 3State Key Laboratory of Bioelectronics (Chien-Shiung Wu Laboratory, Southeast University, Nanjing, China*These authors contributed equally to this workAbstract: Traditional Chinese medicine is gradually becoming a new source of anticancer drugs. One such example is wogonin, which is cytotoxic to various cancer cell lines in vitro. However, due to its low water solubility, wogonin is restricted to clinical administration. Recently, the application of drug-coated magnetic nanoparticles (MNPs to increase water solubility of the drug and to enhance its chemotherapeutic efficiency has attracted much attention. In this study, wogonin was conjugated with the drug delivery system of MNPs by mechanical absorption polymerization to fabricate wogonin-loaded MNPs. It was demonstrated that MNPs could strengthen wogonin-induced cell inhibition, apoptosis, and cell cycle arrest in Raji cells by methylthiazol tetrazolium assay, flow cytometer assay, and nuclear 4',6-diamidino-2-phenylindole staining. Furthermore, the molecular mechanisms of these phenomena were explored by western blot, in which the protein levels of caspase 8 and caspase 3 were increased significantly while those of survivin and cyclin E were decreased significantly in wogonin-MNPs group. These findings suggest that the combination of wogonin and MNPs provides a promising strategy for lymphoma therapy.Keywords: wogonin, magnetic nanoparticles, Raji cell, apoptosis, cell cycle, caspase 8, caspase 3, survivin, cyclin E

Reply to Comment on ``Effects of fast and slow solar wind on the correlations between interplanetary medium and geomagnetic activity'' by C. B. Wang and J. K. Chao

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Ballatore, Paola

2003-10-01

The paper [2002] (the paper commented) shows that the statistical significance of the correlations between the interplanetary parameters and the geomagnetic indices (Kp or Dst) is generally less significant during the fastest solar wind. On the other hand, at these fast solar wind periods, the significance of the Kp versus Dst correlation is equal to or higher than during slower solar wind. These results, together with further observations related to substorm periods and with previously published findings, are interpreted in terms of a difference in the interplanetary-magnetospheric coupling for solar wind faster or slower than a certain threshold (identified between about 500 and 600 km/s). Specifically, it is suggested that a possible linear approximation of the geomagnetic-interplanetary coupling is more appropriate during solar wind speed (Vsw) slower than this threshold, being nonlinear processes more dominant during the fastest speeds. This reply highlights that the correlation coefficients shown by [2003] are in agreement with these findings. In addition, Wang and Chao show that the statistical significance of the difference between the correlation coefficients for Vsw ≥ 550 km/s and those for Vsw Wang and Chao is wrong. Moreover, Wang and Chao recalculate the correlations between the interplanetary parameters and the ΔDst instead of Dst; in fact they note that the time derivative of this index (not the index itself) is driven by the interplanetary medium. Here we note that on the contrary, they show that the correlation coefficients between interplanetary parameters and Dst are larger than those obtained using ΔDst and we suggest a possible interpretation in terms of nonlinearity.

Fasxiator, a novel factor XIa inhibitor from snake venom, and its site-specific mutagenesis to improve potency and selectivity.

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Chen, W; Carvalho, L P D; Chan, M Y; Kini, R M; Kang, T S

2015-02-01

Bleeding remains a major limitation of standard anticoagulant drugs that target the extrinsic and common coagulation pathways. Recently, intrinsic coagulation factors are increasingly being investigated as alternative targets for developing anticoagulant drugs with lower bleeding risk. Goals were to (i) identify novel anticoagulants selectively targeting intrinsic coagulation pathway and (ii) characterize and further improve the properties of the identified anticoagulants. We have isolated and sequenced a specific factor XIa (FXIa) inhibitor, henceforth named Fasxiator, from the venom of the banded krait snake, Bungarus fasciatus. It is a Kunitz-type protease inhibitor that prolonged activated partial thromboplastin time without significant effects on prothrombin time. Fasxiator was recombinantly expressed (rFasxiator), purified, and characterized to be a slow-type inhibitor of FXIa that exerts its anticoagulant activities (doubled activated partial thromboplastin time at ~ 3 μmol L(-1) ) by selectively inhibiting human FXIa in in vitro assays. A series of mutants were subsequently generated to improve the potency and selectivity of recombinant rFasxiator. rFasxiatorN17R,L19E showed the best balance between potency (IC50 ~ 1 nmol L(-1) ) and selectivity (> 100 times). rFasxiatorN17R,L19E is a competitive slow-type inhibitor of FXIa (Ki  = 0.86 nmol L(-1) ), possesses anticoagulant activity that is ~ 10 times stronger in human plasma than in murine plasma, and prolonged the occlusion time of mice carotid artery in FeCl3 -induced thrombosis models. We have isolated an exogenous FXIa specific inhibitor, engineered it to improve its potency by ~ 1000 times and demonstrated its in vitro and in vivo efficacy. These proof-of-principle data supported the further development of Fasxiator as a novel anticoagulant candidate. © 2014 International Society on Thrombosis and Haemostasis.

Nonlinear and Nonequilibrium Spin Injection in Magnetic Tunneling Junctions

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Guo, Hong

2007-03-01

Quantitative analysis of charge and spin quantum transport in spintronic devices requires an atomistic first principles approach that can handle nonlinear and nonequilibrium transport conditions. We have developed an approach for this purpose based on real space density functional theory (DFT) carried out within the Keldysh nonequilibrium Green's function formalism (NEGF). We report theoretical analysis of nonlinear and nonequilibrium spin injection and quantum transport in Fe/MgO/Fe trilayer structures as a function of external bias voltage. Devices with well relaxed atomic structures and with FeO oxidization layers are investigated as a function of external bias voltage. We also report calculations of nonequilibrium spin injection into molecular layers and graphene. Comparisons to experimental data will be presented. Work in collaborations with: Derek Waldron, Vladimir Timochevski (McGill University); Ke Xia (Institute of Physics, Chinese Academy of Science, Beijing, China); Eric Zhu, Jian Wang (University of Hong Kong); Paul Haney, and Allan MacDonald (University of Texas at Austin).

All-atom simulation study of protein PTH(1-34) by using the Wang-Landau sampling method

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Kim, Seung-Yeon [Korea National University of Transportation, Chungju (Korea, Republic of); Kwak, Woo-Seop [Chosun University, Gwangju (Korea, Republic of)

2014-12-15

We perform simulations of the N-terminal 34-residue protein fragment PTH(1-34), consisting of 581 atoms, of the 84-residue human parathyroid hormone by using the all-atom ECEPP/3 force field and the Wang-Landau sampling method. Through a massive high-performance computation, the density of states and the partition function Z(T), as a continuous function of T, are obtained for PTH(1-34). From the continuous partition function Z(T), the partition function zeros of PTH(1-34) are evaluated for the first time. From both the specific heat and the partition function zeros, two characteristic transition temperatures are obtained for the all-atom protein PTH(1-34). The higher transition temperature T{sub 1} and the lower transition temperature T{sub 2} of PTH(1-34) can be interpreted as the collapse temperature T{sub θ} and the folding temperature T{sub f} , respectively.

Epigenetic information in gametes: Gaming from before fertilization. Comment on ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

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Shi, Junchao; Zhang, Xudong; Liu, Ying; Chen, Qi

2017-03-01

In their interesting article [1] Wang et al. proposed a mathematical model based on evolutionary game theory [2] to tackle the fundamental question in embryo development, that how sperm and egg interact with each other, through epigenetic processes, to form a zygote and direct successful embryo development. This work is based on the premise that epigenetic reprogramming (referring to the erasure and reconstruction of epigenetic marks, such as DNA methylation and histone modifications) after fertilization might be of paramount importance to maintain the normal development of embryos, a premise we fully agree, given the compelling experimental evidence reported [3]. Wang et al. have specifically chosen to employ the well-studied DNA methylation reprogramming process during mammalian early embryo development, as a basis to develop their mathematical model, namely epigenetic game theory (epiGame). They concluded that the DNA methylation pattern in mammalian early embryo could be formulated and quantified, and their model can be further used to quantify the interactions, such as competition and/or cooperation of expressed genes that maximize the fitness of embryos. The efforts by Wang et al. in quantitatively and systematically analyzing the beginning of life apparently hold value and represent a novel direction for future embryo development research from both theoretical and experimental biologists. On the other hand, we see their theory still at its infancy, because there are plenty more parameters to consider and there are spaces for debates, such as the cases of haploid embryo development [4]. Here, we briefly comment on the dynamic process of epigenetic reprogramming that goes beyond DNA methylation, a dynamic interplay that involves histone modifications, non-coding RNAs, transposable elements et al., as well as the potential input of the various types of 'hereditary' epigenetic information in the gametes - a game that has started before the fertilization.

Grateloupia tenuis Wang et Luan sp. nov. (Halymeniaceae, Rhodophyta): a new species from South China Sea based on morphological observation and rbcL gene sequences analysis.

Science.gov (United States)

Yu, Ling; Wang, Hongwei; Luan, Rixiao

2013-01-01

Grateloupia tenuis Wang et Luan sp. nov. is a new species described from Lingshui, Hainan Province, South China Sea. Based on the external form and internal structure, combined with rbcL gene sequence analysis, Grateloupia tenuis is distinct from other Grateloupia species as follows: (1) thalli is slippery and cartilaginous in texture; possess fewer branches, relatively slight main axes, and two or three dichotomous branches; (2) cortex is 5-6 layers; medulla is solid when young, but hollow in old branches; reproductive structures are dispersed in main axes of thalli and lower portions of branchlets; exhibits Grateloupia-type auxiliary cell ampullae; (3) the four studied G. tenuis sequences were positioned in a large Grateloupia clade of Halymeniaceae, which included sister group generitype G. filicina with 68 bp differences; G. tenuis was determined to be a sister taxon to the G. catenata, G. ramosissima, G. orientalis, and G. filiformis subclade. The pairwise distances between G. tenuis and these species were 39 to 50 bp. The sequences of G. tenuis differed by 81-108 bp from the sequences of other samples in Grateloupia; there are 114-133 bp changes between G. tenuis and other genera of Halymeniaceae. In final analysis, we considered Grateloupia tenuis Wang et Luan sp. nov. to be a new species of genus Grateloupia.

Effects of heavy metals and light levels on the biosynthesis of carotenoids and fatty acids in the macroalgae Gracilaria tenuistipitata (var. liui Zhang & Xia

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Ernani Pinto

2011-04-01

Full Text Available We present here the effect of heavy metals and of different light intensities on the biosynthesis of fatty acids and pigments in the macroalga Gracilaria tenuistipitata (var. liui Zhang & Xia. In order to verify the fatty acid content, gas chromatography with flame ionization detection (GC-FID was employed. Pigments (major carotenoids and chlorophyl-a were monitored by liquid chromatography with diode array detection (HPLC-DAD. Cultures of G. tenuistipitata were exposed to cadmium (Cd2+, 200 ppb and copper (Cu2+, 200 ppb, as well as to different light conditions (low light: 100 µmol.photons.m-2.s-1, or high light: 1000 µmol.photons.m-2.s-1. Cd2+ and Cu2+ increased the saturated and monounsaturated fatty acid content [14:0, 16:0, 18:0, 18:1 (n-7 and 18:1 (n-9] and all major pigments (violaxanthin, antheraxanthin, lutein, zeaxanthin, chlorophyll-a and β-carotene. Both heavy metals decreased the levels of polyunsaturated fatty acids (PUFA [18:2 (n-6, 18:3 (n-6, 18:5 (n-4, 20:4 (n-6, 20:5 (n-3, 22:6 (n-3]. G. tenuistipitata cultures were exposed to high light intensity for five days and no statistically significant differences were observed in the content of fatty acids. On the other hand, the levels of pigments rose markedly for chlorophyll-a and all of the carotenoids studied.

Entropic sampling of simple polymer models within Wang-Landau algorithm

International Nuclear Information System (INIS)

Vorontsov-Velyaminov, P N; Volkov, N A; Yurchenko, A A

2004-01-01

In this paper we apply a new simulation technique proposed in Wang and Landau (WL) (2001 Phys. Rev. Lett. 86 2050) to sampling of three-dimensional lattice and continuous models of polymer chains. Distributions obtained by homogeneous (unconditional) random walks are compared with results of entropic sampling (ES) within the WL algorithm. While homogeneous sampling gives reliable results typically in the range of 4-5 orders of magnitude, the WL entropic sampling yields them in the range of 20-30 orders and even larger with comparable computer effort. A combination of homogeneous and WL sampling provides reliable data for events with probabilities down to 10 -35 . For the lattice model we consider both the athermal case (self-avoiding walks, SAWs) and the thermal case when an energy is attributed to each contact between nonbonded monomers in a self-avoiding walk. For short chains the simulation results are checked by comparison with the exact data. In WL calculations for chain lengths up to N = 300 scaling relations for SAWs are well reproduced. In the thermal case distribution over the number of contacts is obtained in the N-range up to N = 100 and the canonical averages - internal energy, heat capacity, excess canonical entropy, mean square end-to-end distance - are calculated as a result in a wide temperature range. The continuous model is studied in the athermal case. By sorting conformations of a continuous phantom freely joined N-bonded chain with a unit bond length over a stochastic variable, the minimum distance between nonbonded beads, we determine the probability distribution for the N-bonded chain with hard sphere monomer units over its diameter a in the complete diameter range, 0 ≤ a ≤ 2, within a single ES run. This distribution provides us with excess specific entropy for a set of diameters a in this range. Calculations were made for chain lengths up to N = 100 and results were extrapolated to N → ∞ for a in the range 0 ≤ a ≤ 1.25

Comment on "Electron impact excitation of N-like ions from the ICFT R-matrix calculation" by HB Wang, G Jiang, XF Li, and ZC He in At. Data Nucl. Data Tables 120 (2018) 373-429

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Aggarwal, Kanti M.

2018-03-01

The paper "Electron impact excitation of N-like ions from the ICFT R-matrix calculation" by Wang et al. [1] lacks details of calculations, presents only limited data, and has a few anomalies, as listed below.

Bulletin of Materials Science | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Bulletin of Materials Science. LI-XIA YANG. Articles written in Bulletin of Materials Science. Volume 34 Issue 2 April 2011 pp 233-237. Shape control synthesis of low-dimensional calcium sulfate · Li-Xia Yang Yan-Feng Meng Ping Yin Ying-Xia Yang Ying-Ying Tang Lai-Fen Qin · More Details Abstract ...

Grateloupia tenuis Wang et Luan sp. nov. (Halymeniaceae, Rhodophyta: A New Species from South China Sea Based on Morphological Observation and rbcL Gene Sequences Analysis

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Ling Yu

2013-01-01

Full Text Available Grateloupia tenuis Wang et Luan sp. nov. is a new species described from Lingshui, Hainan Province, South China Sea. Based on the external form and internal structure, combined with rbcL gene sequence analysis, Grateloupia tenuis is distinct from other Grateloupia species as follows: (1 thalli is slippery and cartilaginous in texture; possess fewer branches, relatively slight main axes, and two or three dichotomous branches; (2 cortex is 5-6 layers; medulla is solid when young, but hollow in old branches; reproductive structures are dispersed in main axes of thalli and lower portions of branchlets; exhibits Grateloupia-type auxiliary cell ampullae; (3 the four studied G. tenuis sequences were positioned in a large Grateloupia clade of Halymeniaceae, which included sister group generitype G. filicina with 68 bp differences; G. tenuis was determined to be a sister taxon to the G. catenata, G. ramosissima, G. orientalis, and G. filiformis subclade. The pairwise distances between G. tenuis and these species were 39 to 50 bp. The sequences of G. tenuis differed by 81–108 bp from the sequences of other samples in Grateloupia; there are 114–133 bp changes between G. tenuis and other genera of Halymeniaceae. In final analysis, we considered Grateloupia tenuis Wang et Luan sp. nov. to be a new species of genus Grateloupia.

Grateloupia tenuis Wang et Luan sp. nov. (Halymeniaceae, Rhodophyta): A New Species from South China Sea Based on Morphological Observation and rbcL Gene Sequences Analysis

Science.gov (United States)

Wang, Hongwei; Luan, Rixiao

2013-01-01

Grateloupia tenuis Wang et Luan sp. nov. is a new species described from Lingshui, Hainan Province, South China Sea. Based on the external form and internal structure, combined with rbcL gene sequence analysis, Grateloupia tenuis is distinct from other Grateloupia species as follows: (1) thalli is slippery and cartilaginous in texture; possess fewer branches, relatively slight main axes, and two or three dichotomous branches; (2) cortex is 5-6 layers; medulla is solid when young, but hollow in old branches; reproductive structures are dispersed in main axes of thalli and lower portions of branchlets; exhibits Grateloupia-type auxiliary cell ampullae; (3) the four studied G. tenuis sequences were positioned in a large Grateloupia clade of Halymeniaceae, which included sister group generitype G. filicina with 68 bp differences; G. tenuis was determined to be a sister taxon to the G. catenata, G. ramosissima, G. orientalis, and G. filiformis subclade. The pairwise distances between G. tenuis and these species were 39 to 50 bp. The sequences of G. tenuis differed by 81–108 bp from the sequences of other samples in Grateloupia; there are 114–133 bp changes between G. tenuis and other genera of Halymeniaceae. In final analysis, we considered Grateloupia tenuis Wang et Luan sp. nov. to be a new species of genus Grateloupia. PMID:24455703

Pengaruh insektisida deltametrin terhadap perilaku orientasi parasitoid Anagrus nilaparvatae (Pang et Wang (Hymenoptera: Mymaridae

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Araz Meilin

2016-09-01

Full Text Available Host searching behaviour by a parasitoid includes orientation to the volatile compounds (odor relesead by host or host plant. The aim of this study was to determine the changes in the orientation behaviour of Anagrus nilaparvatae (Pang et Wang, the egg parasitoid of rice brown planthoppers (Nilaparvata lugens (Stål, after being exposed to sublethal concentrations of deltamethrin. The impact of residue on plants to the behaviour of parasitoid was also studied. The sublethal concentrations (LC10 and LC40 used were 0.023 ppm and 2.235 ppm, respectively. Deltamethrin applied to the rice plants were 12.5 ppm and 6.25 ppm, and its effect was observed at 3 hours, 1, 3 and 7 days after application. Orientation behavior was studied using Y-tube olfactometer. Application of deltamethrin at subletal concentration reduced the ability of surviving A. nilaparvatae to detect odors (volatile ompounds released by the host, N. lugens. The higher the concentration of deltamethrin applied to the parasitoid or to the rice plants, the more prominent effect observed in the changing in the parasitoid behavious, in particular disruption to the parasitoid’s orientation to find their host. As consequences, effects of deltamethrin may lead to reduce the effectiveness of A. nilaparvatae as biological control agents in the field as a result of declining their searching capacity. 

The Role of Factor XIa (FXIa) Catalytic Domain Exosite Residues in Substrate Catalysis and Inhibition by the Kunitz Protease Inhibitor Domain of Protease Nexin 2*

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Su, Ya-Chi; Miller, Tara N.; Navaneetham, Duraiswamy; Schoonmaker, Robert T.; Sinha, Dipali; Walsh, Peter N.

2011-01-01

To select residues in coagulation factor XIa (FXIa) potentially important for substrate and inhibitor interactions, we examined the crystal structure of the complex between the catalytic domain of FXIa and the Kunitz protease inhibitor (KPI) domain of a physiologically relevant FXIa inhibitor, protease nexin 2 (PN2). Six FXIa catalytic domain residues (Glu98, Tyr143, Ile151, Arg3704, Lys192, and Tyr5901) were subjected to mutational analysis to investigate the molecular interactions between FXIa and the small synthetic substrate (S-2366), the macromolecular substrate (factor IX (FIX)) and inhibitor PN2KPI. Analysis of all six Ala mutants demonstrated normal Km values for S-2366 hydrolysis, indicating normal substrate binding compared with plasma FXIa; however, all except E98A and K192A had impaired values of kcat for S-2366 hydrolysis. All six Ala mutants displayed deficient kcat values for FIX hydrolysis, and all were inhibited by PN2KPI with normal values of Ki except for K192A, and Y5901A, which displayed increased values of Ki. The integrity of the S1 binding site residue, Asp189, utilizing p-aminobenzamidine, was intact for all FXIa mutants. Thus, whereas all six residues are essential for catalysis of the macromolecular substrate (FIX), only four (Tyr143, Ile151, Arg3704, and Tyr5901) are important for S-2366 hydrolysis; Glu98 and Lys192 are essential for FIX but not S-2366 hydrolysis; and Lys192 and Tyr5901 are required for both inhibitor and macromolecular substrate interactions. PMID:21778227

Reflection and transmission characteristics of a layer obeying the two-pressure field poroelastic phenomenological model of Berryman and Wang.

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Kachkouch, F; Franklin, H; Tinel, A

2018-07-01

The characteristics of the reflection and transmission by a fluid-loaded double porosity layer are studied. The medium obeys the two-pressure field poroelastic phenomenological model of Berryman and Wang. The open pore hydraulic conditions applied at the interfaces yield factorized expressions for the coefficients exhibiting on the one hand a separation allowing to distinguish between symmetrical and antisymmetrical motions and on the other hand the way each of the three dilatational waves associate with the shear wave. The numerical study done for a layer of Berea sandstone saturated by water shows clearly the role of each of the dilatational waves. There are peculiarities such as the absence of the fundamental antisymmetrical mode (zero order) and a singular behaviour of the symmetrical fundamental mode. The low frequency approximation for this latter is derived from the proposed formulas and compared with the numerical results. Copyright © 2018 Elsevier B.V. All rights reserved.

Simple deterministic models and applications. Comment on "Coupled disease-behavior dynamics on complex networks: A review" by Z. Wang et al.

Science.gov (United States)

Yang, Hyun Mo

2015-12-01

Currently, discrete modellings are largely accepted due to the access to computers with huge storage capacity and high performance processors and easy implementation of algorithms, allowing to develop and simulate increasingly sophisticated models. Wang et al. [7] present a review of dynamics in complex networks, focusing on the interaction between disease dynamics and human behavioral and social dynamics. By doing an extensive review regarding to the human behavior responding to disease dynamics, the authors briefly describe the complex dynamics found in the literature: well-mixed populations networks, where spatial structure can be neglected, and other networks considering heterogeneity on spatially distributed populations. As controlling mechanisms are implemented, such as social distancing due 'social contagion', quarantine, non-pharmaceutical interventions and vaccination, adaptive behavior can occur in human population, which can be easily taken into account in the dynamics formulated by networked populations.

王弼《老子注》的詮釋辨證/ Interpretative Dialectics of Wang Bi’s Exegesis of Lao-Tzu

Directory of Open Access Journals (Sweden)

Jung-Tao TSAI

2012-09-01

Wang Bi, the most prominent scholar of metaphysics of the Wei and Jin Dynasties, was an unprecedented genius throughout the history of Chinese philosophy. In this article, the author examines the brilliant contributions made by Lin Li Zhen, Yu Dun Kang and Rudolf G. Wagner, who are noticed for their research of Exegesis of Lao-Tzu. It is a synthesis of the directions of investigation, approaches, and significant findings they have come up with. Among the three interpretations, Lin focuses on the explanation of Wang’s metaphysic thinking while Yu emphasizes Wang’s secular concerns by proposing the “philosophy of thoroughness” and political holism. As for Wagner, he approaches this work with the views of linguistic philosophy and suggests refined stylistics as interpretative strategy, which functions to enrich the textual contents.

Tubeimoside-1 induces glioma apoptosis through regulation of Bax/Bcl-2 and the ROS/Cytochrome C/Caspase-3 pathway

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Jia G

2015-01-01

Full Text Available Geng Jia,1,* Qiang Wang,2,* Rong Wang,2,* Danni Deng,2 Lian Xue,2 Naiyuan Shao,1 Yi Zhang,1 Xiwei Xia,1 Feng Zhi,2 Yilin Yang1,2 1Department of Neurosurgery, Third Affiliated Hospital of Soochow University, Jiangsu, People’s Republic of China; 2Modern Medical Research Center, Third Affiliated Hospital of Soochow University, Jiangsu, People’s Republic of China * These authors contributed equally to this workBackground: Tubeimoside-1 (TBMS1 is a natural compound isolated from tubeimoside, which has been widely used as a traditional Chinese herbal medicine. The purpose of the present study is to investigate the anti-tumor effect and the underling mechanism of TBMS1 on glioma cancer cells.Methods: The MTT assay was performed to evaluate the effect of TBMS1 on glioma cell proliferation. The fluorescent microscopy and flow cytometry analysis were performed to evaluate the effect of TBMS1 on glioma cell apoptosis. The Western blot analysis was used to evaluate the protein change.Results: TBMS1 inhibited glioma cancer cell proliferation in a dose- and time-dependent manner. Fluorescent microscopy and flow cytometry analysis demonstrated that TBMS1 induced glioma cell apoptosis in a concentration-dependent manner. Western blotting showed that TBMS1 induced apoptosis by increasing the expression of Bax and downregulating the level of Bcl-2. Furthermore, we found that TBMS1 induced apoptosis by increasing the concentration of reactive oxygen species through the release of Cytochrome C and activation of Caspase-3.Conclusion: These findings indicate that TBMS1 may be developed as a possible therapeutic agent for the management of glioma. Keywords: Tubeimoside-1, glioma, proliferation, apoptosis

Novel strategy of stents in thyroid mass: a case series report of managing severely dyspneic patients

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Bhandari A

2017-10-01

Full Text Available Adheesh Bhandari,* Ying-hao Wang,* Shi-xu Lv, Er-jie Xia, Ou-Chen Wang Department of Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China *These authors contributed equally to this work Background: Tracheal and bronchial stenosis is a life-threatening condition causing difficulty in breathing and even severe respiratory distress. The silicone tracheobronchial stents were placed using the rigid bronchoscopy into the trachea of severe dyspneic patients and they exhibited symptomatic improvement as well as a rise in the saturation of oxygen. The bronchial stents were applicable to many extensive malignant airway stenosis patients, such as those with esophageal cancer, lung cancer, and laryngeal cancer. But the effectiveness of bronchial stents for thyroid cancer is not certain.Case presentation: Here, we report 3 emergency patients with a thyroid mass referred to our hospital because of grade 4 dyspnea according to the American Thoracic Society shortness of breath guidelines. The main clinical symptoms were severe dyspnea and stridor. The radiographic examination and tomographic examination showed the narrowing and displacement of the trachea. To the best of our knowledge, ideal airway management for the massive thyroid mass was considered to be temporary tracheobronchial stent placement pre-operation.Conclusion: In our study, we applied the tracheobronchial stent to massive thyroid mass patients with dyspnea and aimed to not only improve preoperative airway obstruction but also to protect the potential airway collapse from post-operative tracheomalacia following extubation. We found that application of tracheobronchial stents may provide a new strategy to dyspneic patients with huge thyroid mass. Keywords: tracheobronchial stents, airway management, tracheal stenosis, dyspnea

Epigenetic battle of the sexes. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

Science.gov (United States)

Wu, Song

2017-03-01

Qian Wang et al. present an interesting framework, named epigenetic game theory, for modeling sex-based epigenetic dynamics during embryogenesis from a new viewpoint of evolutionary game theory [1]. That is, epigenomes of sperms and oocytes may coordinate through either cooperation or competition, or both, to affect the fitness of embryos. The work uses a set of ordinary differential equations (ODEs) to describe longitudinal trajectories of DNA methylation levels in both parental and maternal gametes and their dependence on each other. The insights gained from this review, i.e. dynamic methylation profiles and their interaction are potentially important to many fields, such as biomedicine and agriculture.

Essays on Korean online game communities: A sense of place: Media and motivation in Korea by the Wang-tta effect; Order and chaos in an ethnography of Korean online game communities

OpenAIRE

Chee, Florence

2005-01-01

Essay 1 : This paper presents an ethnographic analysis of the different ways Korean game players establish community. I look at Korean PC game rooms as "third places,", and peer relations associated with online video gaming activities. A synthesis of the Korean concept "Wang-tta" and application of the TEDA Ethos protocol provides extra insight into the motivations to excel at digital games and one of the strong drivers of such community membership. Essay 2: This paper explores the dichotomy ...

Nuclear Structure in China 2010

Science.gov (United States)

Bai, Hong-Bo; Meng, Jie; Zhao, En-Guang; Zhou, Shan-Gui

2011-08-01

fragmentation at the intermediate energy / C. W. Ma ... [et al.].Systematic study of spin assignment and dynamic moment of inertia of high-j intruder band in [symbol]In / K. Y. Ma ... [et al.] -- Signals of diproton emission from the three-body breakup channel of [symbol]Al and [symbol]Mg / Ma Yu-Gang ... [et al.] -- Uncertainties of Th/Eu and Th/Hf chronometers from nucleus masses / Z. M. Niu ... [et al.] -- The chiral doublet bands with [symbol] configuration in A[symbol]100 mass region / B. Qi ... [et al.] -- [symbol] formation probabilities in nuclei and pairing collectivity / Chong Qi -- A theoretical prospective on triggered gamma emission from [symbol]Hf[symbol] isomer / ShuiFa Shen ... [et al.] -- Study of nuclear giant resonances using a Fermi-liquid method / Bao-Xi Sun -- Rotational bands in doubly odd [symbol]Sb / D. P. Sun ... [et al.] -- The study of the neutron N=90 nuclei / W. X. Teng ... [et al.] -- Dynamical modes and mechanisms in ternary reaction of [symbol]Au+[symbol]Au / Jun-Long Tian ... [et al.] -- Dynamical study of X(3872) as a D[symbol] molecular state / B. Wang ... [et al.] -- Super-heavy stability island with a semi-empirical nuclear mass formula / N. Wang ... [et al.] -- Pseudospin partner bands in [symbol]Sb / S. Y. Wang ... [et al.] -- Study of elastic resonance scattering at CIAE / Y. B. Wang ... [et al.] -- Systematic study of survival probability of excited superheavy nuclei / C. J. Xia ... [et al.] -- Angular momentum projection of the Nilsson mean-field plus nearest-orbit pairing interaction model / Ming-Xia Xie ... [et al.] -- Possible shape coexistence for [symbol]Sm in a reflection-asymmetric relativistic mean-field approach / W. Zhang ... [et al.] -- Nuclear pairing reduction due to rotation and blocking / Zhen-Hua Zhang -- Nucleon pair approximation of the shell model: a review and perspective / Y. M. Zhao ... [et al.] -- Band structures in doubly odd [symbol]I / Y. Zheng ... [et al.] -- Lifetimes of high spin states in [symbol]Ag / Y

Risky choice with heuristics: reply to Birnbaum (2008), Johnson, Schulte-Mecklenbeck, and Willemsen (2008), and Rieger and Wang (2008).

Science.gov (United States)

Brandstätter, Eduard; Gigerenzer, Gerd; Hertwig, Ralph

2008-01-01

E. Brandstätter, G. Gigerenzer, and R. Hertwig (2006) showed that the priority heuristic matches or outperforms modifications of expected utility theory in predicting choice in 4 diverse problem sets. M. H. Birnbaum (2008) argued that sets exist in which the opposite is true. The authors agree--but stress that all choice strategies have regions of good and bad performance. The accuracy of various strategies systematically depends on choice difficulty, which the authors consider a triggering variable underlying strategy selection. Agreeing with E. J. Johnson, M. Schulte-Mecklenbeck, and M. C. Willemsen (2008) that process (not "as-if") models need to be formulated, the authors show how quantitative predictions can be derived and test them. Finally, they demonstrate that many of Birnbaum's and M. O. Rieger and M. Wang's (2008) case studies championing their preferred models involved biased tests in which the priority heuristic predicted data, whereas the parameterized models were fitted to the same data. The authors propose an adaptive toolbox approach of risky choice, according to which people first seek a no-conflict solution before resorting to conflict-resolving strategies such as the priority heuristic. (c) 2008 APA, all rights reserved

EPIDERMAL MORPHOLOGY OF WEST AFRICAN OKRA ...

African Journals Online (AJOL)

Administrator

stem peels were obtained from a slight cut on the tenth internodes. Peels from fruit ... xia l su rfa ce. A b a xia l su rfa ce. Adaxial surface. Abaxial surface. L e n g th. (µ m. ) ..... Variations in epidermal cell shape of both adaxial and abaxial surfaces ...

A new concept: Epigenetic game theory. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

Science.gov (United States)

Zheng, Xiu-Deng; Tao, Yi

2017-03-01

The evolutionary significance of the interaction between paternal and maternal genomes in fertilized zygotes is a very interesting and challenging question. Wang et al. developed the concept of epigenetic game theory, and they try to use this concept to explain the interaction between paternal and maternal genomes in fertilized zygotes [1]. They emphasize that the embryogenesis can be considered as an ecological system in which two highly distinct and specialized gametes coordinate through either cooperation or competition, or both, to maximize the fitness of embryos under Darwinian selection. More specifically, they integrate game theory to model the pattern of coordination of paternal genome and maternal genomes mediated by DNA methylation dynamics, and they called this epigenetic game theory.

王友仁点穴开合按动法针对踝关节扭伤推拿经验浅析%Discussion on WANG You-ren's Treatment for Sprain of Ankle with Andong Therapy of Pressing Acupoint Combined with Joint Switching

Institute of Scientific and Technical Information of China (English)

包庆旭

2017-01-01

This article focused on WANG You-ren chief physician's Andong therapy theory system, systematically summarized the treatment ideas and characteristics of acute phase for the sprain of ankle. Combined with typical cases, details of WANG You-ren chief physician's treatment with specific press method, remote press method, holographic press method, and corresponding to the press method for the acupoints principle were introduced. WANG You-ren chief physician also proposed early treatment and active protection when people have sprain of ankle, with a purpose to achieve the good efficacy, such as relieve acute pain, reduce swelling, and few sequelae.%本文重点对王友仁主任医师以按动疗法理论体系为纲要,对踝关节扭伤急性期的治疗思路和特色手法进行系统总结,并结合典型病例,详细介绍王友仁主任医师用特定按动法、远端按动法、全息按动法、对应按动法为取穴原则,以达到点穴镇痛在先、开合按动顺筋归位在后的推拿治疗方法.王友仁主任医师提出踝关节扭伤后应及早治疗、积极防护,达到急者镇痛、消肿,缓者后遗症少的理念,在临床上获得满意疗效.

Using game theory to investigate the epigenetic control mechanisms of embryo development: Comment on: "Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition" by Qian Wang et al.

Science.gov (United States)

Zhang, Le; Zhang, Shaoxiang

2017-03-01

A body of research [1-7] has already shown that epigenetic reprogramming plays a critical role in maintaining the normal development of embryos. However, the mechanistic quantitation of the epigenetic interactions between sperms and oocytes and the related impact on embryo development are still not clear [6,7]. In this study, Wang et al., [8] develop a modeling framework that addresses this question by integrating game theory and the latest discoveries of the epigenetic control of embryo development. Copyright © 2017 Elsevier B.V. All rights reserved.

Pressure-induced transition in the grain boundary of diamond

Science.gov (United States)

Chen, J.; Tang, L.; Ma, C.; Fan, D.; Yang, B.; Chu, Q.; Yang, W.

2017-12-01

Equation of state of diamond powder with different average grain sizes was investigated using in situ synchrotron x-ray diffraction and a diamond anvil cell (DAC). Comparison of compression curves was made for two samples with average grain size of 50nm and 100nm. The two specimens were pre-pressed into pellets and loaded in the sample pressure chamber of the DAC separately to minimized differences of possible systematic errors for the two samples. Neon gas was used as pressure medium and ruby spheres as pressure calibrant. Experiments were conducted at room temperature and high pressures up to 50 GPa. Fitting the compression data in the full pressure range into the third order Birch-Murnaghan equation of state yields bulk modulus (K) and its pressure derivative (K') of 392 GPa and 5.3 for 50nm sample and 398GPa and 4.5 for 100nm sample respectively. Using a simplified core-shell grain model, this result indicates that the grain boundary has an effective bulk modulus of 54 GPa. This value is similar to that observed for carbon nanotube[1] validating the recent theoretical diamond surface modeling[2]. Differential analysis of the compression cures demonstrates clear relative compressibility change at the pressure about 20 GPa. When fit the compression data below and above this pressure separately, the effect of grain size on bulk modulus reverses in the pressure range above 20 GPa. This observation indicates a possible transition of grain boundary structure, likely from sp2 hybridization at the surface[2] towards sp3like orbital structure which behaves alike the inner crystal. [1] Jie Tang, Lu-Chang Qin, Taizo Sasaki, Masako Yudasaka, Akiyuki Matsushita, and Sumio Iijima, Compressibility and Polygonization of Single-Walled Carbon Nanotubes under Hydrostatic Pressure, Physical Review Letters, 85(9), 1187-1198, 2000. [2] Shaohua Lu, Yanchao Wang, Hanyu Liu, Mao-sheng Miao, and Yanming Ma, Self-assembled ultrathin nanotubes on diamond (100) surface, Nature

Fabrication and characterization of drug-loaded nano-hydroxyapatite/polyamide 66 scaffolds modified with carbon nanotubes and silk fibroin

Directory of Open Access Journals (Sweden)

Yao MZ

2016-11-01

Full Text Available Meng-Zhu Yao,1 Ming-Yi Huang-Fu,1 Hui-Na Liu,1 Xia-Rong Wang,1 Xiaoxia Sheng,2 Jian-Qing Gao1 1Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, 2Hangzhou SoliPharma Co., Ltd, Hangzhou, Zhejiang, People’s Republic of China Abstract: Nano-hydroxyapatite/polyamide 66 (nHA/PA66 porous scaffolds were fabricated by a phase inversion method. Carbon nanotubes (CNTs and silk fibroin (SF were used to modify the surface of the nHA/PA66 scaffolds by freeze-drying and cross-linking. Dexamethasone was absorbed to the CNTs to promote the osteogenic differentiation of bone mesenchymal stem cells (BMSCs. The cell viability of BMSCs was investigated by changing the concentration of the CNT dispersion, and the most biocompatible scaffold was selected. In addition, the morphology and mechanical property of the scaffolds were investigated. The results showed that the nHA/PA66 scaffolds modified with CNTs and SF met the requirements of bone tissue engineering scaffolds. The dexamethasone-loaded CNT/SF-nHA/PA66 composite scaffold promoted the osteogenic differentiation of BMSCs, and the drug-loaded scaffolds are expected to function as effective bone tissue engineering scaffolds. Keywords: BMSCs, tissue engineering, porous scaffold, carbon nanotubes, silk fibroin, surface modification, dexamethasone

Cuprous oxide nanoparticles selectively induce apoptosis of tumor cells

Directory of Open Access Journals (Sweden)

Wang Y

2012-05-01

Full Text Available Ye Wang,1,2,* Xiao-Yuan Zi,1,* Juan Su,1 Hong-Xia Zhang,1 Xin-Rong Zhang,3 Hai-Ying Zhu,1 Jian-Xiu Li,1 Meng Yin,3 Feng Yang,3 Yi-Ping Hu,11Department of Cell Biology, 2School of Clinical Medicine, 3Department of Pharmaceuticals, Second Military Medical University, Shanghai, People's Republic of China*Authors contributed equally.Abstract: In the rapid development of nanoscience and nanotechnology, many researchers have discovered that metal oxide nanoparticles have very useful pharmacological effects. Cuprous oxide nanoparticles (CONPs can selectively induce apoptosis and suppress the proliferation of tumor cells, showing great potential as a clinical cancer therapy. Treatment with CONPs caused a G1/G0 cell cycle arrest in tumor cells. Furthermore, CONPs enclosed in vesicles entered, or were taken up by mitochondria, which damaged their membranes, thereby inducing apoptosis. CONPs can also produce reactive oxygen species (ROS and initiate lipid peroxidation of the liposomal membrane, thereby regulating many signaling pathways and influencing the vital movements of cells. Our results demonstrate that CONPs have selective cytotoxicity towards tumor cells, and indicate that CONPs might be a potential nanomedicine for cancer therapy.Keywords: nanomedicine, selective cytotoxicity, apoptosis, cell cycle arrest, mitochondrion-targeted nanomaterials

‘Quadrilateral’ in Philosophy and Bie-modernism (Comments on Aleš Erjavec’s “Zhuyi: From Absence to Bustle? Some Comments on Wang Jianjiang's Article ‘The Bustle and the Absence of Zhuyi’”

Directory of Open Access Journals (Sweden)

Wang Jianjiang

2017-09-01

Full Text Available Aleš Erjavec proposed the global philosophical quadrilateral, giving Chinese philosophy, aesthetics, and humanities an expectation. However, the realization of this expectation hinges on the question whether Chinese philosophy as well as aesthetics and the humanities can rid themselves of the staggering level of ‘voice’ and develop their ‘speech’. To make ‘speech’, any nation should have its own idea, theory and Zhuyi. How to overcome the embarrassment that ‘quadrilateral’ expectation implies? Time spatialization and four-phase development theories of the Bie-modern, and great leap forward pause theory have provided an answer. The quadrilateral expectation as shown by Aleš Erjavec, is encountering the antagonism between ‘cosmopolitanism’ and ‘nationalism’. The key to resolving this antagonism is ‘my’ original achievement consisting of ‘Chinese traditional philosophy, Western philosophy, Marxism and I (myself’. Bie-modernism is a Zhuyi of self-regulation, self-renewal and self-transcendence and of their practical implementation.   Article received: May 21, 2017; Article accepted: May 24, 2017; Original scholarly paper How to cite this article: Jianjiang, Wang. "‘Quadrilateral’ in Philosophy and Bie-modernism (Comments on Aleš Erjavec’s “Zhuyi: From Absence to Bustle? Some Comments on Wang Jianjiang's Article ‘The Bustle and the Absence of Zhuyi’”." AM Journal of Art and Media Studies 13 (2017: 123-142. doi: 10.25038/am.v0i13.190

Comparison of imaging-based gross tumor volume and pathological volume determined by whole-mount serial sections in primary cervical cancer

Directory of Open Access Journals (Sweden)

Zhang Y

2013-07-01

Full Text Available Ying Zhang,1,* Jing Hu,1,* Jianping Li,1 Ning Wang,1 Weiwei Li,1 Yongchun Zhou,1 Junyue Liu,1 Lichun Wei,1 Mei Shi,1 Shengjun Wang,2 Jing Wang,2 Xia Li,3 Wanling Ma4 1Department of Radiation Oncology, 2Department of Nuclear Medicine, 3Department of Pathology, 4Department of Radiology, Xijing Hospital, Xi'an, People's Republic of China*These authors contributed equally to this workObjective: To investigate the accuracy of imaging-based gross tumor volume (GTV compared with pathological volume in cervical cancer.Methods: Ten patients with International Federation of Gynecology and Obstetrics stage I–II cervical cancer were eligible for investigation and underwent surgery in this study. Magnetic resonance imaging (MRI and fluorine-18 fluorodeoxyglucose positron emission tomography (18F-FDG PET/computed tomography (CT scans were taken the day before surgery. The GTVs under MRI and 18F-FDG PET/CT (GTV-MRI, GTV-PET, GTV-CT were calculated automatically by Eclipse treatment-planning systems. Specimens of excised uterine cervix and cervical cancer were consecutively sliced and divided into whole-mount serial sections. The tumor border of hematoxylin and eosin-stained sections was outlined under a microscope by an experienced pathologist. GTV through pathological image (GTV-path was calculated with Adobe Photoshop.Results: The GTVs (average ± standard deviation delineated and calculated under CT, MRI, PET, and histopathological sections were 19.41 ± 11.96 cm3, 12.66 ± 10.53 cm3, 11.07 ± 9.44 cm3, and 10.79 ± 8.71 cm3, respectively. The volume of GTV-CT or GTV-MR was bigger than GTV-path, and the difference was statistically significant (P 0.05. Spearman correlation analysis showed that GTV-CT, GTV-MRI, and GTV-PET were significantly correlated with GTV-path (P < 0.01. There was no significant difference in the lesion coverage factor among the three modalities.Conclusion: The present study showed that GTV defined under 40% of maximum standardized

Retracted: Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation, by L Wang, SG Zellmer, DM Printzenhoff and NA Castle. British Journal of Pharmacology, volume 172(20): 4905-4918, published in October 2015; DOI 10.1111/bph.13259.

Science.gov (United States)

2018-07-01

The above article, published by the British Journal of Pharmacology in October 2015 (https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.13259), has been retracted by agreement between the authors, the journal Editor in Chief and John Wiley & Sons Limited. The retraction has been agreed owing to the discovery of errors in the chemical structure of the synthetic compounds generated. The corrected structure is now available in the article PF-06526290 can both enhance and inhibit conduction through voltage gated sodium channels by L Wang, SG Zellmer, DM Printzenhoff and NA Castle, 2018, https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14338. Reference Wang L, Zellmer SG, Printzenhoff DM, Castle NA (2015). Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation. Br J Pharmacol 172: 4905-4918. https://doi.org/10.1111/bph.13259. © 2018 The British Pharmacological Society.

Multiple-Input Data Acquisition System (MIDAS) for Measuring the Carbon Content in Soil Using Inelastic Neutron Scattering

Energy Technology Data Exchange (ETDEWEB)

Warburton, William K. [XIA LLC, Hayward, CA (United States)

2014-01-24

This report describes work funder under STTR grants Phase I and II and carried out jointly by XIA LLC and Brookhaven National Laboratory (BNL). The project goal was to develop a mobile nuclear activation analysis instrument that could be towed behind a tractor to document soil carbon levels in agricultural lands for carbon credit certification. XIA developed large NaI(Tl) detectors with integrated digital pulse processors controlled over USB 2.0 and delivered 16 of these units to BNL for integration into the prototype instrument, together with the necessary software to calibrate them and collect data. For reasons that are unknown to XIA, the BNL participants never completed the prototype vehicle, performed system integration, or carried out the proposed qualification and field tests, leaving the project incomplete.

古今文献中与“尪痹”相关的病证名研究%A Study on the Disorders Relevant with“ Wang Bi”in the Ancient and Modern Literatures

Institute of Scientific and Technical Information of China (English)

孟小燕; 王育林

2016-01-01

Differentiation of disease and differentiation of syndrome are equally important in the di-agnosis and treatment of TCM. Disease is the entire process of some abnormal life state and syndrome is a cer-tain stage in the abnormal process in the life. The terms of disease and syndrome are related with each other. In the study of the ancient and modern literatures on the term Wang Bi(尪痹),it was found that the term for syndrome was also involved. Wang Bi(尪痹)is the new term of a disease proposed by TCM master,Jiao Shude. By investigating the name and origin of the disease,Wan Bi was identified as the term of syndrome. The connection of Wang Bi(尪痹)and Wan Bi was attempted to build so as to contribute to the correct un-derstanding of the disease and construction of medical history in TCM.%中医诊治强调辨病与辨证并重，中医学探讨某病时兼及“病”“证”。疾病指人体某种异常生命状态的全过程，而证候是这个全部生命异常过程中的某个阶段。病证名即与病、证发生发展相关的称谓。在考察古今文献中与“尪痹”相关称谓时，发现还有证名的存在，因此为客观全面，该文使用了“病证名”而非“病名”的概念。“尪痹”是已故中医学家焦树德提出的新病名，考察古今文献中与“尪痹”相关的称谓，可以发现还有证名的存在。对这些病证的名实与源流进行考察，考证“尪痹”之源，辨析病证名“顽痹”。力图呈现与“尪痹”相关病证名的大致面貌，以利于准确把握这一疾病，俾于中医疾病史的建构。

Scaling behavior can be tricky: Comment on "Universal scaling for the dilemma strength in evolutionary games" by Z. Wang et al.

Science.gov (United States)

Hui, Pak Ming; Xu, Chen

2015-09-01

Evolutionary game theory is a powerful tool for studying the emergence of cooperation among competing individuals [1]. Popularly studied games include the prisoner's dilemma [2], snowdrift game [3] and stag hunt game [4]. They have been extensively studied for the extent of cooperative behavior under different dilemma strengths. Generally, the games can be defined by a 2 × 2 matrix and thus four payoff elements, T, R, P, and S, for the possible payoffs to players when they use pure strategies against each other. Detailed definitions of the four payoffs are given in the review by Wang et al. [5]. For simplicity, it is often the case that fewer parameters are invoked, e.g. a single parameter [3] and more generally two parameters [6]. Generally speaking, reducing the number of parameters has the effect of restricting the system to a certain subspace of the unreduced case. In addition, the spatial structures, such as a well-mixed population or a population forming a complex network, that govern the competing relationship and environment of the agents, and the evolutionary rules, that govern how agents update their strategies, are vital in determining how cooperation evolves, as well documented in the references of [5].

A role of Yueju in fast-onset antidepressant action on major depressive disorder and serum BDNF expression: a randomly double-blind, fluoxetine-adjunct, placebo-controlled, pilot clinical study

Directory of Open Access Journals (Sweden)

Wu R

2015-08-01

Full Text Available Ruyan Wu,1,* Dandan Zhu,1,* Youchun Xia,2,* Haosen Wang,2 Weiwei Tao,1 Wenda Xue,1 Baomei Xia,1 Li Ren,1 Xin Zhou,1 Guochun Li,3 Gang Chen1 1Center for Translational Systems Biology and Neuroscience, Key Laboratory of Integrative Biomedicine of Brain Diseases, Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 2The Fourth People’s Hospital of Taizhou, Taizhou, People’s Republic of China; 3School of Basic Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China *These authors contributed equally to this work Introduction: Conventional antidepressants, including fluoxetine, have a major disadvantage in delayed onset of efficacy. Yueju, an herbal medicine used to treat mood disorders was recently found to exhibit rapid antidepressant effects. The present study was conducted to evaluate the role of Yueju in rapidly acting on major depressive disorder (MDD.Methods: Participants were MDD patients with scores of 24-item Hamilton Depression Rating Scale (HDRS-24 ≥20 and without history of antidepressant use. They randomly received daily oral doses of Yueju (23 g/day plus fluoxetine (20 mg/day (experimental group or placebo plus fluoxetine (control group for 7 days. HDRS-24 was used as the primary outcome measurement at baseline, and on days 1, 3, 5, and 7. Concentrations of serum brain-derived neurotrophic factor (BDNF were assessed at baseline and on days 1 and 7.Results: In all, 18 participants met the criteria for data analysis. Compared to baseline level, only experimental group showed significant decrease of HDRS-24 score from day 3 to day 7 (P<0.05. Experimental group also showed significant improvement compared with control group from day 3 to day 7 (P<0.05. No correlation between treatment outcomes with serum BDNF levels was observed. However, experimental group showed significant correlation for serum BDNF level on day 1 with day 7 (r=0.721, P=0.028, whereas the control

Variação temporal do gradiente radial de o/h a partir de uma amostra de nebulosas planetárias

Science.gov (United States)

Maciel, W. J.; Costa, R. D. D.; Uchida, M. M. M.

2003-08-01

Gradientes radiais de abundância são observados no disco de nossa Galáxia e também em outras galáxias espirais. No caso da Galáxia, o principal problema relativo aos gradientes é sua variação temporal, que constitui um dos principais vínculos aos modelos de evolução química da Galáxia. As nebulosas planetárias são particularmente interessantes no estudo dos gradientes e suas variações, tanto espaciais como temporais. São objetos brilhantes, podendo ser observadas a grandes distâncias, e têm abundâncias relativamente precisas de diversos elementos químicos. Além disso, sendo originadas de estrelas com massas entre 0.8 e 8 massas solares na sequência principal, incluem objetos com idades e populações diferentes, o que as torna especialmente interessantes ao estudo da variação temporal dos gradientes. Neste trabalho, apresentamos resultados recentes sobre a variação temporal do gradiente de O/H a partir de uma amostra contendo cerca de 200 nebulosas, para as quais obtivemos distâncias por métodos estatísticos. As abundâncias foram parcialmente obtidas a partir de observações em Itajubá e La Silla, sendo as restantes obtidas da literatura. Os resultados mostram, pela primeira vez, evidências de um achatamento do gradiente de O/H, de -0.11 dex/kpc para -0.06 dex/kpc nos últimos 9 giga-anos ou de -0.08 dex/kpc para -0.06 dex/kpc nos últimos 5 giga-anos. Esses valores apresentam um bom acordo com alguns modelos recentes para a evolução química da Galáxia. (FAPESP/CNPq)

Game theory in epigenetic reprogramming. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

Science.gov (United States)

Hsu, Fei-Man; Chen, Pao-Yang

2017-03-01

Von Neumann and Morgenstern published the Theory of Games and Economic Behavior in 1944, describing game theory as a model in which intelligent rational decision-makers manage to find their best strategies in conflict, cooperative or other mutualistic relationships to acquire the greatest benefit [1]. This model was subsequently incorporated in ecology to simulate the ;fitness; of a species during natural selection, designated evolutionary game theory (EGT) [2]. Wang et al. proposed ;epiGame;, taking paternal and maternal genomes as ;intelligent; players that compete, cooperate or both during embryogenesis to maximize the fitness of the embryo [3]. They further extended game theory to an individual or single cell environment. During early zygote development, DNA methylation is reprogrammed such that the paternal genome is demethylated before the maternal genome. After the reset, the blastocyst is re-methylated during embryogenesis. At that time, the paternal and maternal genomes have a conflict of interest related to the expression of their own genes. The proposed epiGame models such interactive regulation between the parental genomes to reach a balance for embryo development (equation (2)).

Vínculos sobre um modelo de quartessência de Chaplygin usando observações do satélite chandra da fração de massa de gás em aglomerados de galáxias

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de Souza, R. S.

2003-08-01

Observações de Supernovas do tipo Ia mostram que a expansão do Universo está acelerando. Segundo as equações de Einstein uma componente com pressão negativa (energia escura) é necessária para explicar a aceleração cósmica. Além da energia escura é usualmente admitido que no Universo há também uma matéria exótica com pressão zero, que é chamada de matéria escura. Essa componente possui um papel fundamental na formação de estruturas no Universo. Recentemente tem se explorado a possibilidade de que matéria e energia escura poderiam ser unificadas através de uma única componente, que tem sido denominada de quartessência. Um exemplo de fluido com essas características é o Gás de Chaplygin Generalizado, que possui uma equação de estado da forma p = -A/ra. Inicialmente consideramos o caso especial a = 1 (gás de Chaplygin) e vinculamos parâmetros do modelo utilizando observações em raios-X do satélite Chandra da fração de massa de gás em aglomerados de galáxias. Uma comparação dos vínculos obtidos com esse teste com outros testes, tais como supernovas e idade do Universo, mostra que esse teste é bastante restritivo. Exibiremos ainda resultados para o caso em que a curvatura é nula e o parâmetro a está compreendido no intervalo -1 < a 1.

Abundâncias químicas de uma amostra de nebulosas planetárias em M51

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Uchida, M. M. M.; Costa, R. D. D.; Maciel, W. J.

2003-08-01

A derivação de abundâncias químicas de nebulosas planetárias permite a investigação dos processos de enriquecimento químico ocorridos durante a evolução das estrelas progenitoras, que têm massas entre 0.8 e 8 massas solares. Adicionalmente as abundâncias de elementos como oxigênio, argônio ou neônio, que não são produzidos por nucleossíntese na progenitora, refletem a evolução do meio interestelar: estrelas menos massivas, de evolução mais lenta, tipicamente originam-se de um meio interestelar mais pobre. Reportamos aqui a derivação de parâmetros físicos e abundâncias químicas de uma amostra de nebulosas planetárias da galáxia M51, uma galáxia de tipo Seyfert 2 pertencente ao Grupo de Sculptor. As observações foram feitas com o telescópio Gemini Norte, usando o espectrógrafo GMOS no modo multi-objeto. Os resultados indicam uma distribuição de abundâncias análoga àquela das planetárias da Galáxia. A amostra observada não permite estabelecer-se com clareza a existência de um gradiente radial como é esperado pelos modelos evolutivos de galáxias expirais; espera-se que uma extensão desta amostra deva indicá-lo posteriormente. (FAPESP/CNPq)

Upregulation of miR-375 level ameliorates morphine analgesic tolerance in mouse dorsal root ganglia by inhibiting the JAK2/STAT3 pathway

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Li HQ

2017-05-01

Full Text Available Haiqin Li, Rong Tao, Jing Wang, Lingjie Xia Department of Clinical Pain, The People’s Hospital of Henan Province, Zhengzhou, People’s Republic of China Abstract: Several lines of evidence indicate that microRNAs (miRNAs modulate tolerance to the analgesic effects of morphine via regulation of pain-related genes, making dysregulation of miRNA levels a clinical target for controlling opioid tolerance. However, the precise mechanisms by which miRNAs regulate opioid tolerance are unclear. In the present study, we noted that the miR-375 level was downregulated but the expression of Janus kinase 2 (JAK2 was upregulated in mouse dorsal root ganglia (DRG following chronic morphine treatment. The miR-375 levels and JAK2 expression were correlated with the progression of morphine tolerance, and upregulation of miR-375 level could significantly hinder morphine tolerance. This was ameliorated by JAK2 knockdown. Prolonged morphine exposure induced the expression of brain-derived neurotrophic factor (BDNF in a time-dependent manner in the DRG. This was regulated by the miR-375 and JAK2–signal transducer and activator of transcription 3 (STAT3 pathway, and inhibition of this pathway decreased BDNF production, and thus, attenuated morphine tolerance. More importantly, we found that miR-375 could target JAK2 and increase BDNF expression in a JAK2/STAT3 pathway-dependent manner. Keywords: morphine tolerance, miR-375, JAK2, BDNF

Cerebellar cryptococcosis characterized by a space-occupying lesion in an immunocompetent non-HIV patient

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Liu BX

2014-12-01

Full Text Available Bi-Xia Liu,1,* Xi-Jian Dai,2,3,* Heng Liu,4,* Hong-Han Gong,3 Yi-Xiang J Wang,2 Lun-Li Zhang1 1Department of Infectious Diseases, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People’s Republic of China; 2Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong; 3Department of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People’s Republic of China; 4Department of Radiology, Affiliated Hospital of Zunyi Medical University, Guizhou, People’s Republic of China *These authors contributed equally to this work Abstract: Central nervous system (CNS cryptococcosis is an opportunistic fungal infection that typically occurs in patients with reduced immunological function, such as patients with AIDS, patients receiving organ transplants, or patients receiving corticosteroid and immunosuppressive therapy. CNS cryptococcosis rarely occurs in immunocompetent patients. CNS cryptococcosis is characterized by meningitis and encephalitis and occasionally forms isolated granulomas. Isolated cerebellar cryptococcoma is a rare condition, especially in immunocompetent patients, and the misdiagnosis rate is high. A definite diagnosis must be based on pathology. To raise awareness of this disease, the clinical data of a patient with cryptococcomas in the right side of the cerebellum are reported. Keywords: cryptococcosis, cerebellar, central nervous system, magnetic resonance imaging, immunosuppressive

Epigallocatechin-3-gallate attenuates apoptosis and autophagy in concanavalin A-induced hepatitis by inhibiting BNIP3

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Li S

2016-02-01

Full Text Available Sainan Li, Yujing Xia, Kan Chen, Jingjing Li, Tong Liu, Fan Wang, Jie Lu, Yingqun Zhou, Chuanyong Guo Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China Background: Epigallocatechin-3-gallate (EGCG is the most effective compound in green tea, and possesses a wide range of beneficial effects, including anti-inflammatory, antioxidant, antiobesity, and anticancer effects. In this study, we investigated the protective effects of EGCG in concanavalin A (ConA-induced hepatitis in mice and explored the possible mechanisms involved in these effects.Methods: Balb/C mice were injected with ConA (25 mg/kg to induce acute autoimmune hepatitis, and EGCG (10 or 30 mg/kg was administered orally twice daily for 10 days before ConA injection. Serum liver enzymes, proinflammatory cytokines, and other marker proteins were determined 2, 8, and 24 hours after the ConA administration.Results: BNIP3 mediated cell apoptosis and autophagy in ConA-induced hepatitis. EGCG decreased the immunoreaction and pathological damage by reducing inflammatory factors, such as TNF-α, IL-6, IFN-γ, and IL-1β. EGCG also exhibited an antiapoptotic and antiautophagic effect by inhibiting BNIP3 via the IL-6/JAKs/STAT3 pathway.Conclusion: EGCG attenuated liver injury in ConA-induced hepatitis by downregulating IL-6/JAKs/STAT3/BNIP3-mediated apoptosis and autophagy. Keywords: concanavalin A, hepatitis, EGCG, autophagy, apoptosis, BNIP3, STAT3, JAKs, IL-6

Accelerator mass spectrometry and its applications in environmental science

International Nuclear Information System (INIS)

Liu Kexin; Li Kun; Ma Hongji; Guo Zhiyu

2001-01-01

Some important work worldwide in environmental science, like urban air pollution, discharges of radioactive wastes from nuclear plants, and global climate change were introduced. Based on the improvements of facility and studies on 14 C dating method, a precision better than 0.5% has been reached for the PKUAMS. A large number of samples have been measured for the Xia-Shang-Zhou Chronology project. 14 C data of PKUAMS have made important contributions to creation of more reliable chronological table of Xia, Shang and Zhou dynasties. The improvements of PKUAMS are of benefit to the applications in environmental science in the future

Yan Sun, Corruption and Market in Contemporary China, Ithaca (N.Y.), Cornell University Press, 2004 et Ning Wang, Making a Market Economy. The Institutional Transformation of a Freshwater Fishery in a Chinese Community, Londres et New York, Routledge, 200

OpenAIRE

Guiheux, Gilles

2008-01-01

Ces deux ouvrages éclairent les conditions dans lesquelles, au cours des 25 dernières années, l’économie de commande a été démantelée et remplacée progressivement par un système de marché. Yan Sun, professeur de sciences politiques, s’intéresse à la corruption dans une double perspective macro et micro. Ning Wang, économiste néo-institutionnaliste, se demande comment, à la faveur des réformes, une région (Jingzhou, au sud du Hubei) s’est convertie à la pisciculture. La corruption est une ques...

Taxonomic review on the subgenus Tripodura Townes (Diptera: Chironomidae: Polypedilum) from China with eleven new species and a supplementary world checklist.

Science.gov (United States)

Zhang, Ruilei; Song, Chao; Qi, Xin; Wang, Xinhua

2016-07-05

The subgenus Tripodura Townes of Polypedilum Kieffer from China including 26 species is reviewed. Eleven new species, named P. (T.) absensilobum Zhang & Wang sp. n., P. (T.) apiculusetosum Zhang & Wang sp. n., P. (T.) arcuatum Zhang & Wang sp. n., P. (T.) bilamella Zhang & Wang sp. n., P. (T.) conghuaense Zhang & Wang sp. n., P. (T.) dengae Zhang & Wang sp. n., P. (T.) mengmanense Zhang & Wang sp. n., P. (T.) napahaiense Zhang & Wang sp. n., P. (T.) parallelum Zhang & Wang sp. n., P. (T.) pollicium Zhang & Wang sp. n. and P. (T.) trapezium Zhang & Wang sp. n. are described and illustrated based on male imagines. Three species, P. (T.) quadriguttatum Kieffer, P. (T.) unifascia (Tokunaga) and P. (T.) udominutum Niitsuma are firstly recorded in China. A key to known male imagines of Chinese species and an updated world checklist of subgenus Tripodura are presented.

Absorption of SO/sub 2/ by pecan (Carya illinoensis (Wang) K. Koch) and alfalfa (Medicago sativa L. ) and its effect on net photosynthesis

Energy Technology Data Exchange (ETDEWEB)

Sisson, W.B.; Booth, J.A.; Throneberry, G.O.

1981-06-01

Absorption rates of SO/sub 2/ by pecan (Carya illinoensis (Wang) K. Koch) leaflets exposed to 2.6, 5.2, and 7.8 mg SO/sub 2/ m/sup -3/ were measured over a 2 h period. SO/sub 2/ was rapidly absorbed by the leaflets in all treatments during the initial 30-50 min; the rate of uptake decreased to a rather constant level thereafter. Total SO/sub 2/ absorbed during the 2 h period was 15.6, 25.6, and 38.9 nmol cm/sup -2/ for the low, medium, and high SO/sub 2/ concentrations, respectively. Reductions in net photosynthetic rates were proportional to ambient SO/sub 2/ concentrations and total SO/sub 2/ absorbed. Partial photosynthetic recovery occurred in all treatments during a 2 hr post-treatment period and full recovery occurred during a 12 h dark period. Exposure to SO/sub 2/ resulted in slight increases in stomatal and boundary layer resistances to CO/sub 2/ and substantial increases in residual resistances. Absorption rates of SO/sub 2/ by alfalfa (Medicago sativa L.) exposed to 5.2 mg SO/sub 2/ m/sup -3/ for 1 h were approximately double those of pecan exposed to the same ambient SO/sub 2/ concentration. Alfalfa net photosynthetic rates were reduced 74% after 1 h exposure to 5.2 mg SO/sub 2/ m/sup -3/ while a depression of 42% occurred in pecan.

Analisis senyawa volatil dari ekstrak tanaman yang berpotensi sebagai atraktan parasitoid telur wereng batang coklat, Anagrus nilaparvatae (Pang et Wang (Hymenoptera: Mymaridae

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Surjani Wonorahardjo

2015-09-01

Full Text Available Plants produce volatiles as communication cues intra- or inter- species. Infested plants by herbivores will produce volatiles as indirect defense mechanism that attracts natural enemies of herbivores. Analysis of volatiles compounds produced by rice plant as result of infested brown plant hopper (BPH, Nilaparvata lugens Stâl, was done to identify compounds in the volatiles that potentially can be used as attractant for egg parasitoids of BPH, Anagrus nilaparvatae (Pang et Wang (Hymenoptera: Mymaridae. This research was an early stage to develop formulation of parasitoid attractant. The research activities include volatiles extraction of infested rice stem by BPH eggs using acetone, n-hexane as the extraction solvents; analyses of volatile compounds with GC-MS; and bioassay of parasitoid orientation behavior to the volatiles using olfactometer methods. Extraction methods applied were maceration and continuous extraction followed by concentration. Bioassay on the parasitoid orientation behavior was done by using Y-tube olfactometer and every lot of bioassay using 30 parasitoid females with 3 replicates. The results showed that the volatile compounds of extract of infested rice stem by BPH eggs comprise of 16 components. The highest proportion of the components extracted with acetone is 2-Pentanone, 4-hydroxy-4-methyl (19,9%, while those with n-hexane is Hexanedioic acid, dioctyl ester (65%. A. nilaparvatae showed positive response to the volatiles extracted from infested rice plant by N. lugens eggs. Therefore, the volatiles can be used as an attractant for the egg A. nilaparvatae to support rice pest management.

Massa do gás e das estrelas em aglomerados: eficiência da formação estelar

Science.gov (United States)

Laganá, T. F.; Lima Neto, G. B.

2003-08-01

Os aglomerados de galáxias apresentam um interesse especial para a cosmologia observacional. Eles são as maiores estruturas ligadas pela gravitação no Universo e relaxadas na região central. A comparação entre a massa do gás intra-aglomerado (responsável por ~25% da massa total, inferida a partir de observações em raios-X), a massa contida nas estrelas (i.e., nas galáxias) e a massa total (incluindo a matéria escura não bariônica), nos dá informações importantes sobre os processos de formação e evolução de aglomerados. Por exemplo, a razão entre a massa do gás e a massa total é uma medida da fração de bárions no Universo (razão entre a matéria bariônica e matéria escura) e, utilizando a densidade de bárions predita pela nucleosíntese primordial, podemos deduzir a densidade de matéria escura no Universo (cf. White et al. 1993). O objetivo deste trabalho é obter as razões entre as massas do gás, estelar (contida nas galáxias), e a total (massa dinâmica). As massas do gás e total são obtidas a partir das análises fotométrica e espectroscópica em raios-X enquanto que a massa estelar é obtida pela análise fotométrica das galáxias. Esta análise foi aplicada ao aglomerado Abell 496 observado pelo satélite XMM-Newton. A massa contida nas galáxias foi estimada a partir da função de luminosidade obtida por Durret et al. (2002). Para determinar as massas dinâmica e do gás nos precisamos determinar os perfis radiais de densidade e temperatura. Nós apresentaremos aqui estes resultados e suas implicações na eficiência da formação estelar em Abell 496.

Nimotuzumab combined with radiotherapy for esophageal cancer: preliminary study of a Phase II clinical trial

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Liang J

2013-11-01

Full Text Available Jun Liang,1 Mingyan E,2 Gang Wu,3 Lujun Zhao,4 Xia Li,5 Xia Xiu,6 Ning Li,1 Bo Chen,1 Zhouguang Hui,1 Jima Lv,1 Hui Fang,1 Yu Tang,1 Nan Bi,1 Wenqing Wang,1 Yirui Zhai,1 Tao Li,1 Dongfu Chen,1 Shuangmei Zou,7 Ning Lu,7 Rolando Perez-Rodríguez,8 Junqi Zheng,9 Luhua Wang11Department of Radiotherapy, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, People's Republic of China; 2Department of Radiotherapy, Cancer Hospital of Harbin Medical University, Harbin, People's Republic of China; 3Department of Radiotherapy, Tongji Cancer Center Hospital, Wuhan, People's Republic of China; 4Department of Radiotherapy, Cancer Hospital of Tianjin Medical University, Tianjin, People's Republic of China; 5Department of Radiotherapy, LiaoNing Province Cancer Hospital, Shenyang, People's Republic of China; 6Department of Radiotherapy, Beijing Hospital, Beijing, People's Republic of China; 7Department of Pathology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, People's Republic of China; 8Center of Molecular Immunology, Havana, Cuba; 9School of Medicine, Tongji University, Shanghai, People's Republic of ChinaObjective: To determine the safety and therapeutic effects of nimotuzumab (h-R3 combined with radiotherapy in esophageal cancer.Methods: This Phase II clinical trial involved 42 patients with stage II (inoperable or refused surgery to stage IV (supraclavicular lymph node metastasis only esophageal cancers treated between November 2008 and July 2010. All patients had squamous cell carcinomas, and all received three-dimensional conformal radiotherapy and 200 mg nimotuzumab per week during radiotherapy.Results: There were 9, 25, and 8 patients with stage II, III and IV disease, respectively. All except two patients received 50–70 Gy radiation; 37 patients (88.1% received more than five nimotuzumab doses. Grade III toxicities (21.4% of all adverse events included esophagitis and gastrointestinal, dermatological and hematological

Topological phase transition in the two-dimensional anisotropic Heisenberg model: A study using the Replica Exchange Wang-Landau sampling

Science.gov (United States)

Figueiredo, T. P.; Rocha, J. C. S.; Costa, B. V.

2017-12-01

Although the topological Berezinskii-Kosterlitz-Thouless transition was for the first time described by 40 years ago, it is still a matter of discussion. It has been used to explain several experiments in the most diverse physical systems. In contrast with the ordinary continuous phase transitions the BKT-transition does not break any symmetry. However, in some contexts it can easily be confused with other continuous transitions, in general due to an insufficient data analysis. The two-dimensional XY (or sometimes called planar rotator) spin model is the fruit fly model describing the BKT transition. As demonstrated by Bramwell and Holdsworth (1993) the finite-size effects are more important in two-dimensions than in others due to the logarithmic system size dependence of the properties of the system. Closely related is the anisotropic two dimensional Heisenberg model (AH). Although they have the same Hamiltonian the spin variable in the former has only two degrees of freedom while the AH has three. Many works treat the AH model as undergoing a transition in the same universality class as the XY model. However, its characterization as being in the BKT class of universality deserve some investigation. This paper has two goals. First, we describe an analytical evidence showing that the AH model is in the BKT class of universality. Second, we make an extensive simulation, using the numerical Replica Exchange Wang-Landau method that corroborate our analytical calculations. From our simulation we obtain the BKT transition temperature as TBKT = 0 . 6980(10) by monitoring the susceptibility, the two point correlation function and the helicity modulus. We discuss the misuse of the fourth order Binder's cumulant to locate the transition temperature. The specific heat is shown to have a non-critical behavior as expected in the BKT transition. An analysis of the two point correlation function at low temperature, C(r) ∝r - η(T), shows that the exponent, η, is consistent

Petrochemistry and zircon U-Pb geochronology of granitic rocks in the Wang Nam Khiao area, Nakhon Ratchasima, Thailand: Implications for petrogenesis and tectonic setting

Science.gov (United States)

Fanka, Alongkot; Tsunogae, Toshiaki; Daorerk, Veerote; Tsutsumi, Yukiyasu; Takamura, Yusuke; Sutthirat, Chakkaphan

2018-05-01

Carboniferous biotite granite, Late Permian hornblende granite, and Triassic biotite-hornblende granite, all of which belong to the Eastern Granite Belt, expose in the Wang Nam Khiao area, Nakhon Ratchasima, northeastern Thailand. The Carboniferous biotite granite is dominated by quartz, K-feldspar, plagioclase, and biotite. The Late Permian hornblende granite contains dominant assemblages of plagioclase, quartz, K-feldspar, hornblende, and minor amount of biotite, while the Triassic biotite-hornblende granite consists of quartz, plagioclase, K-feldspar with small amounts of biotite, and hornblende. The REE patterns with steep decrease from light to heavy REE together with the LILE (e.g. K, Sr) enrichment and depletion of some particular HFSE (e.g. Nb, Ti) indicate low degree of partial melting. Mineral chemistry of biotite and hornblende in the granites reflects crystallization from hydrous calc-alkaline arc-derived magmas possibly formed by subduction. Amphibole-plagioclase thermometry and Al-in-hornblende barometry indicate that the Late Permian hornblende granite and the Triassic biotite-hornblende granite may have equilibrated at 3.0-5.8 kbar/700-820 °C and 2.0-3.2 kbar/600-750 °C, respectively, in the middle-upper crust (about 10-15 km depth). Zircon U-Pb geochronology of the Carboniferous biotite granite, Late Permian hornblende granite and Triassic biotite-hornblende granite yielded intrusion ages of 314.6-284.9 Ma, 253.4 Ma, and 237.8 Ma, respectively, which implies multiple episodes of arc-magmatism formed by Palaeo-Tethys subduction beneath Indochina Terrane during Late Carboniferous/Early Permian, Late Permian and Middle Triassic.

Effects of erythromycin on γ-glutamyl cysteine synthetase and interleukin-1β in hyperoxia-exposed lung tissue of premature newborn rats

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Cheng Cai

2014-09-01

Full Text Available Objetivo: Explorar o efeito da eritromicina sobre lesões pulmonares induzidas por hiperóxia. Métodos: Uma prole de ratos Sprague-Dawley (SD prematuros com um dia de vida foi dividida aleatoriamente em quatro grupos: grupo 1 ar + cloreto de sódio, grupo 2 ar + eritromicina, grupo 3 hiperóxia + cloreto de sódio e grupo 4 hiperóxia + eritromicina. Com um, sete e 14 dias de exposição, foram detectadas Glutationa (GSH e Interleucina-1 beta (IL-1 beta pelo ensaio imunossorvente ligado à enzima (ELISA, e o ácido bicinconinico (BCA foi utilizado para detectar a proteína GSH. O mRNA da γ-glutamil-cisteina-sintetase (γ-GCS foi detectado por reação em cadeia da polimerase via transcriptase reversa (RT-PCR. Resultados: Comparadas ao grupo 1, as expressões do mRNA da GSH e da γ-GCS no grupo 3 aumentaram significativamente com um e sete dias de exposição (p < 0,05, porém a expressão de mRNA da γ-GCS diminuiu significativamente aos 14 dias; a expressão de IL-1 beta no grupo 3 aumentou significativamente aos 7 dias de exposição (p < 0,05 e diminuiu significativamente aos 14 dias. Comparadas ao grupo 3, as expressões do mRNA da GSH e da γ-GCS no grupo 4 aumentaram significativamente com um, sete e 14 dias de exposição (p < 0,05, porém as expressões de GSH mostraram uma tendência de queda aos 14 dias; a expressão de IL-1 beta no grupo 4 foi reduzida significativamente com um e sete dias de exposição (p < 0,05. Conclusões: As variações de IL-1 beta e GSH mediadas por oxidantes estão envolvidas no desenvolvimento de lesão pulmonar induzida por hiperóxia. A eritromicina poderá regular positivamente a atividade da γ-GCS, aumentando a expressão de GSH, inibindo os níveis de interleucina-1beta mediada por oxidante e aliviando a lesão pulmonar induzida por hiperóxia por meio de um efeito antioxidante.

Utilization of BIA-Derived Bone Mineral Estimates Exerts Minimal Impact on Body Fat Estimates via Multicompartment Models in Physically Active Adults.

Science.gov (United States)

Nickerson, Brett S; Tinsley, Grant M

2018-03-21

The purpose of this study was to compare body fat estimates and fat-free mass (FFM) characteristics produced by multicompartment models when utilizing either dual energy X-ray absorptiometry (DXA) or single-frequency bioelectrical impedance analysis (SF-BIA) for bone mineral content (BMC) in a sample of physically active adults. Body fat percentage (BF%) was estimated with 5-compartment (5C), 4-compartment (4C), 3-compartment (3C), and 2-compartment (2C) models, and DXA. The 5C-Wang with DXA for BMC (i.e., 5C-Wang DXA ) was the criterion. 5C-Wang using SF-BIA for BMC (i.e., 5C-Wang BIA ), 4C-Wang DXA (DXA for BMC), 4C-Wang BIA (BIA for BMC), and 3C-Siri all produced values similar to 5C-Wang DXA (r > 0.99; total error [TE] FFM characteristics (i.e., FFM density, water/FFM, mineral/FFM, and protein/FFM) for 5C-Wang DXA and 5C-Wang BIA were each compared with the "reference body" cadavers of Brozek et al. 5C-Wang BIA FFM density differed significantly from the "reference body" in women (1.103 ± 0.007 g/cm 3 ; p FFM and mineral/FFM were significantly lower in men and women when comparing 5C-Wang DXA and 5C-Wang BIA with the "reference body," whereas protein/FFM was significantly higher (all p ≤ 0.001). 3C-Lohman BIA and 3C-Lohman DXA produced error similar to 2C models and DXA and are therefore not recommended multicompartment models. Although more advanced multicompartment models (e.g., 4C-Wang and 5C-Wang) can utilize BIA-derived BMC with minimal impact on body fat estimates, the increased accuracy of these models over 3C-Siri is minimal. Copyright © 2018 The International Society for Clinical Densitometry. Published by Elsevier Inc. All rights reserved.

Effect of Jian-Pi-Zhi-Dong Decoction on striatal glutamate and γ-aminobutyric acid levels detected using microdialysis in a rat model of Tourette syndrome

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Zhang W

2016-05-01

Full Text Available Wen Zhang,1,* Li Wei,2,* Wenjing Yu,1 Xia Cui,1 Xiaofang Liu,2 Qian Wang,1 Sumei Wang2 1Department of Pediatrics, The Third Affiliated Hospital, 2Department of Pediatrics, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of China *These authors contributed equally to this work Background: Jian-Pi-Zhi-Dong Decoction (JPZDD is a dedicated treatment of Tourette syndrome (TS. The balance of neurotransmitters in the cortico-striato-pallido-thalamo-cortical network is crucial to the occurrence of TS and related to its severity. This study evaluated the effect of JPZDD on glutamate (Glu and γ-aminobutyric acid (GABA and their receptors in a TS rat model.Materials and methods: Rats were divided into four groups (n=12 each. TS was induced in three of the groups by injecting them with 3,3'-iminodipropionitrile for 7 consecutive days. Two model groups were treated with tiapride (Tia or JPZDD, while the control and the remaining model group were gavaged with saline. Behavior was assessed by stereotypic score and autonomic activity. Striatal Glu and GABA contents were detected using microdialysis. Expressions of N-methyl-D-aspartate receptor 1 and GABAA receptor (GABAAR were observed using Western blot and real-time polymerase chain reaction.Results: Tia and JPZDD groups had decreased stereotypy compared with model rats; however, the JPZDD group showed a larger decrease in stereotypy than the Tia group at a 4-week time point. In a spontaneous activity test, the total distance of the JPZDD and Tia groups was significantly decreased compared with the model group. The Glu levels of the model group were higher than the control group and decreased with Tia or JPZDD treatment. The GABA level was higher in the model group than the control group. Expressions of GABAAR protein in the model group were higher than in the control group. Treatment with Tia or JPZDD reduced the expression of GABAAR protein. In the case of the m

In vitro characterization and in vivo evaluation of nanostructured lipid curcumin carriers for intragastric administration

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Fang M

2012-10-01

Full Text Available Min Fang, Yilin Jin, Wei Bao, Hui Gao, Mengjin Xu, Di Wang, Xia Wang, Ping Yao, Liegang LiuDepartment of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, and Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan, People’s Republic of ChinaBackground: Curcumin has a variety of pharmacological effects. However, poor water solubility and low oral bioavailability limit its clinical utility. A delivery system for nanostructured lipid carriers has been reported to be a promising approach to enhancing the oral absorption of curcumin. The aim of the present study was to investigate the pharmacokinetics, tissue distribution, and relative bioavailability of curcumin in rats after a single intragastric dose of a nanostructured lipid curcumin carrier formulation.Methods: Nanostructured lipid curcumin carriers were prepared using the ethanol dripping method and characterized in terms of the particle size, polydispersity index, zeta potential, differential scanning calorimetry, drug-loading capacity, encapsulation efficiency, and in vitro release. The pharmacokinetics and tissue distribution of nanostructured lipid curcumin carriers and curcumin suspension were compared after intragastric administration.Results: Nanostructured lipid curcumin carriers showed a significantly higher peak plasma concentration (564.94 ± 14.98 ng/mL versus 279.43 ± 7.21 ng/mL, P < 0.01, a shorter time taken to reach peak plasma concentration (0.5 ± 0.01 hour versus 1.0 ± 0.12 hour, P < 0.01, and a greater AUC0–∞ (820.36 ± 25.11 mg × hour/L versus 344.11 ± 10.01 mg × hour/L, P < 0.05 compared with curcumin suspension. In the tissue distribution studies, curcumin could be detected in the spleen, heart, liver, kidneys, lungs, and brain. Following intragastric administration of the nanostructured lipid curcumin

Chloroquine enhances the efficacy of cisplatin by suppressing autophagy in human adrenocortical carcinoma treatment

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Qin L

2016-03-01

Full Text Available Liang Qin,1,* Tianyuan Xu,1,* Leilei Xia,1 Xianjin Wang,1 Xiang Zhang,1 Xiaohua Zhang,1 Zhaowei Zhu,1 Shan Zhong,1 Chuandong Wang,2 Zhoujun Shen1 1Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 2Key Laboratory of Stem Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China *These authors contributed equally to this work Background: It has been demonstrated that chloroquine (CQ enhances the efficacy of chemotherapy. However, little is known about whether CQ could enhance the efficacy of cisplatin (DDP in the treatment of adrenocortical carcinoma (ACC. In this study, we explore the efficacy and mechanism by which CQ affects DDP sensitivity in human ACC in vitro and in vivo.Methods: The autophagic gene Beclin-1 expression was detected by immunohistochemistry, and the protein levels were analyzed using immunoblotting assays of ACC tissues and normal adrenal cortex tissues. The ACC SW13 cells were treated with DDP and/or CQ. The cell viability assay was performed using the MTT method. Qualitative autophagy detection was performed by monodansylcadaverine staining of autophagic vacuoles. Annexin V-fluorescein isothiocyanate/propidium iodide double staining was used to count cell apoptosis by flow cytometry. The autophagy-related protein (Beclin-1, LC3, and p62 and apoptosis relative protein (Bax and Bcl-2 levels were evaluated with Western blot analysis. Furthermore, a murine model of nude BALB/c mice bearing SW13 cell xenografts was established to evaluate the efficacy of concomitant therapy.Results: The expression of the autophagic gene Beclin-1 was significantly downregulated in ACC tissues compared to normal adrenal cortex tissues. The Beclin-1 protein level in ACC tissues was lower than that in normal adrenal cortex tissues (P<0.05. In vitro concomitant therapy (DDP and CQ was more

Multifunctional selenium nanoparticles as carriers of HSP70 siRNA to induce apoptosis of HepG2 cells

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Li Y

2016-07-01

Full Text Available Yinghua Li,1 Zhengfang Lin,1 Mingqi Zhao,1 Tiantian Xu,1 Changbing Wang,1 Huimin Xia,1,* Hanzhong Wang,2,* Bing Zhu1,* 1Guangzhou Women and Children’s Medical Center, Guangzhou, Guangdong, 2State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, People’s Republic of China *These authors contributed equally to this work Abstract: Small interfering RNA (siRNA as a new therapeutic modality holds promise for cancer treatment, but it is unable to cross cell membrane. To overcome this limitation, nanotechnology has been proposed for mediation of siRNA transfection. Selenium (Se is a vital dietary trace element for mammalian life and plays an essential role in the growth and functioning of humans. As a novel Se species, Se nanoparticles have attracted more and more attention for their higher anticancer efficacy. In the present study, siRNAs with polyethylenimine (PEI-modified Se nanoparticles (Se@PEI@siRNA have been demonstrated to enhance the apoptosis of HepG2 cells. Heat shock protein (HSP-70 is overexpressed in many types of human cancer and plays a significant role in several biological processes including the regulation of apoptosis. The objective of this study was to silence inducible HSP70 and promote the apoptosis of Se-induced HepG2 cells. Se@PEI@siRNA were successfully prepared and characterized by various microscopic methods. Se@PEI@siRNA showed satisfactory size distribution, high stability, and selectivity between cancer and normal cells. The cytotoxicity of Se@PEI@siRNA was lower for normal cells than tumor cells, indicating that these compounds may have fewer side effects. The gene-silencing efficiency of Se@PEI@siRNA was significantly much higher than Lipofectamine 2000@siRNA and resulted in a significantly reduced HSP70 mRNA and protein expression in cancer cells. When the expression of HSP70 was diminished, the function of cell protection was also removed and cancer cells became more

A reviewof the pharmacologicalmechanism of traditional Chinese ...

African Journals Online (AJOL)

A reviewof the pharmacologicalmechanism of traditional Chinese medicine in the intervention of coronary heart disease and stroke. W Zhang, K Gao, K Gao, J Liu, J Liu, H Zhao, H Zhao, J Wang, J Wang, Y Li, Y Li, G Murtaza, G Murtaza, J Chen, J Chen, W Wang, W Wang ...

Bulletin of Materials Science | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Bulletin of Materials Science; Volume 35; Issue 4. CuO/TiO2 nanocrystals grown on graphene as visible-light responsive photocatalytic hybrid materials. Yuan Fang Rijing Wang Guohua Jiang He Jin Yin Wang Xinke Sun Sheng Wang Tao Wang. Volume 35 Issue 4 August 2012 pp 495-499 ...

Research Article Special Issue

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pc

2017-10-17

Oct 17, 2017 ... simulated in Microwave Office (AWR Design Environment) based on ... such as Radio Frequency (RF), microwave circuits and electronic ..... [8] Xu Z, Xia H. Miniaturized multilayer dual-mode substrate integrated waveguide ...

Fake "Returnee" Earns 4 Million through Fraudulent Marriages: More than Ten Women Fall for His Claims of Being a Boss and Possessing a House and Car

Science.gov (United States)

Chinese Education and Society, 2005

2005-01-01

This article discusses the case of Wang Ruiliang. Ms. Huang filed a case against Wang Jun, alleging that he had defrauded her. Ms. Huang met a man named Wang Jun in April 2002 through a certain matrimonial agency. Before they had been together for very long, Wang Jun asked to borrow money from Ms. Huang, claiming that he was having difficulties in…

Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy

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Li J

2016-02-01

Full Text Available Jingjing Li,1 Kan Chen,1 Sainan Li,1 Jiao Feng,1 Tong Liu,1 Fan Wang,1 Rong Zhang,1,2 Shizan Xu,1,2 Yuqing Zhou,1,3 Shunfeng Zhou,1,3 Yujing Xia,1 Jie Lu,1 Yingqun Zhou,1 Chuanyong Guo1 1Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 2The First Clinical Medical College of Nanjing Medical University, Nanjing, 3Department of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China Abstract: Liver fibrosis is a dynamic reversible pathological process in the development of chronic liver disease to cirrhosis. However, the current treatments are not administered for a long term due to their various side effects. Autophagy is initiated to decompose damaged or excess organelles, which had been found to alter the progression of liver fibrosis. In this article, we hypothesized that fucoidan from Fucus vesiculosus may attenuate liver fibrosis in mice by inhibition of the extracellular matrix and autophagy in carbon tetrachloride- and bile duct ligation-induced animal models of liver fibrosis. The results were determined using enzyme-linked immunosorbent assay, quantitative real-time polymerase chain reaction, Western blotting, and immunohistochemical staining. Fucoidan from F. vesiculosus could inhibit the activation of hepatic stellate cells and the formation of extracellular matrix and autophagosomes, and its effect may be associated with the downregulation of transforming growth factor beta 1/Smads pathways. Fucoidan, as an autophagy and transforming growth factor beta 1 inhibitor, could be a promising potential therapeutic agent for liver fibrosis. Keywords: liver cirrhosis, hepatic stellate cells, bile duct ligation

Reference: 178 [Arabidopsis Phenome Database[Archive

Lifescience Database Archive (English)

Full Text Available 15723040 2005 Mar EMBO reports Berg Howard|Dietrich Charles|Ge Xiaochun|Li Guojing|Matsuno Michiyo|Xia Yiji ...psis aspartic protease functions as an anti-cell-death component in reproduction and embryogenesis. 3 282-8

Disassembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients

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Adler Charles

2009-07-01

Full Text Available Abstract Correction to Nural H, He P, Beach T, Sue L, Xia W, Shen Y. Disassembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients Molecular Neurodegeneration 2009, 4:23.

(SDS-PAGE) and random amplified polymorphic DNA

African Journals Online (AJOL)

bgunni

2011-11-09

Nov 9, 2011 ... testing and classification. FAO Manual on Sericulture, 3: 72-73. ... Sun Y, Xia N, Stapleton CMA (2005). Relationship between ... Saratchandra B, Rahman SAS, Singh KC, Chakraborti R, Urs SR. (2006). Genetic diversity and ...

Dynamics of photosynthesis in Eichhornia crassipes Solms of ...

African Journals Online (AJOL)

hope&shola

2010-10-25

Oct 25, 2010 ... Solms of Jiangsu of China and their influencing factors. Li Xia* ... crassipes to rapidly grow but not good enough for it to show the maximum internal photosynthetic ... environmental factors, such as light intensity, temperature.

A distância e o conteúdo estelar da região HII gigante G333.1-0.4 - vínculos para a taxa de formação estelar da galáxia

Science.gov (United States)

Figuerêdo, E.; Damineli, A.; Blum, R.; Conti, P.

2003-08-01

Neste trabalho apresentamos imagens de alta resolução angular da região HII gigante G333.1-0.4 obtidas através dos filtros J, H e K no telescópio de 4-m do CTIO. Este trabalho faz parte de um estudo de regiões HII gigantes no infravermelho próximo que tem por objetivo estudar a natureza da formação de estrelas massivas e traçar a estrutura espiral de nossa galáxia. Nossa determinação da distância é baseada no método da paralaxe espectroscópica de estrelas OB localizadas na seqüência principal de idade zero (ZAMS) do Diagrama HR. No caso de G333.1-0.4, a magnitude aparente das estrelas localizadas na ZAMS indica que a distância não pode ser maior do que o limite inferior determinado por técnica rádio (2,8 kpc). Resultados semelhantes foram encontrados para regiões estudadas anteriormente, reforçando a idéia de que a taxa de formação estelar na Via Láctea é menor do que o determinado a partir de dados rádio. Nossos resultados mais recentes sobre o conteúdo estelar de G333.1-0.4 revelaram vários objetos que possuem cores bastante avermelhadas (H-K > 2,0). Nós identificamos estes objetos usando os diagramas cor-cor e cor-magnitude dos aglomerados. Estes objetos apresentam um forte excesso em emissão na banda K e possivelmente se tratam de estrelas do tipo OB envolvidas por um disco/envelope circumestelar espesso. O estudo da função de massa inical desta região, em conjunto com resultados de nossos trabalhos anteriores, aponta para uma IMF independente da posição galática. A contagem de estrelas nos fornece um valor para o número de fótons no contínuo de Lyman que corrobora com a afirmação de que G333.1-0.4 se encontra mais próxima da menor distância determinada por rádio.

Effects of Huang Bai (Phellodendri Cortex and Three Other Herbs on GnRH and GH Levels in GT1–7 and GH3 Cells

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Sun Haeng Lee

2016-01-01

Full Text Available The present study was to evaluate the effects of Huang Bai, Zhi Mu, Mai Ya, and Xia Ku Cao on hormone using the GT1–7 and GH3 cells. The GT1–7 and GH3 cell lines were incubated with DW; DMSO; and 30, 100, or 300 μg/mL of one of the four extract solutions in serum-free media for 24 hours. The MTT assay was performed to determine the cytotoxicity of the four herbs. The GT1–7 and GH3 cells were incubated in DW, estradiol (GT1–7 only, or noncytotoxic herb solutions in serum-free medium for 24 hours. A quantitative RT-PCR and western blot were performed to measure the GnRH expression in GT1–7 cells and GH expression in GH3 cells. Huang Bai, Zhi Mu, Xia Ku Cao, and Mai Ya inhibited the GnRH mRNA expression in GT1–7 cells, whereas Huang Bai enhanced GH mRNA expression in GH3 cells. Additionally, Xia Ku Cao inhibited GnRH protein expression in GT1–7 cells and Huang Bai promoted GH protein expression in GH3 cells. The findings suggest that Huang Bai can delay puberty by inhibiting GnRH synthesis in the hypothalamus while also accelerating growth by promoting GH synthesis and secretion in the pituitary.

Apparent characteristics and taxonomic study of macroalgae in Pattani Bay

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Naruemol Pianthumdee

2007-07-01

Full Text Available 2A survey on macroalgae in Pattani Bay was carried out to build up a database resource for the management of algae in the area. From February 2004 to March 2005, samples of macroalgae from 10 sites were randomly collected monthly. Macroalgae were found at 4 sites in the north of the bay, namely Laem Tachi, Lighthouse, Ban Bu Di and Ban Ta Lo Samilae; 3 sites in the east, namely Ban Da To, the Yaring River Mouth and Ban Bang Pu and only one site in the south at Ban Tanyong Lu Lo. Twelve species of 3 divisions of macroalgae were detected. They were Division Cyanophyta, Lyngbya majuscula (Dillwyn Harvey ex Gomont; Division Chlorophyta; Ulva intestinalis Linnaeus, U. pertusa Kjellman and U. reticulata Forsskal, Rhizoclonium riparium (Roth Harvey, R. tortuosum Kutzing, Chaetomorpha crassa (C. Agardh Kutzing and Cladophora sp.; and Division Rhodophyta, namely Gracilaria tenuistipitata Chang et Xia, G. fisheri (Xia et Abbott Abbott, Zhang et Xia, Hypnea spinella (C. Agardh Kutzing and Acanthophora spicifera (Vahl B∅rgesen. Among them, four species were new recordings at Pattani Bay: Lyngbya majuscula, Rhizoclonium riparium, R. tortuosum and Acanthophora spicifera. Most of these seaweeds were found at the east sites in the dry season from February to September 2004 and from January to March 2005. Only a few species could be found in the wet season from November to December 2004.

Structural Principles in the Development of Cyclic Peptidic Enzyme Inhibitors

Science.gov (United States)

Xu, Peng; Andreasen, Peter A.; Huang, Mingdong

2017-01-01

This review summarizes our studies in the development of small cyclic peptides for specifically modulating enzyme activity. Serine proteases share highly similar active sites but perform diverse physiological and pathological functions. From a phage-display peptide library, we isolated two mono-cyclic peptides, upain-1 (CSWRGLENHRMC) and mupain-1 (CPAYSRYLDC), which inhibit the activity of human and murine urokinase-type plasminogen activators (huPA and muPA) with Ki values in the micromolar or sub-micromolar range, respectively. The following affinity maturations significantly enhanced the potencies of the two peptides, 10-fold and >250-fold for upain-1 and mupain-1, respectively. The most potent muPA inhibitor has a potency (Ki = 2 nM) and specificity comparable to mono-clonal antibodies. Furthermore, we also found an unusual feature of mupain-1 that its inhibitory potency can be enhanced by increasing the flexibility, which challenges the traditional viewpoint that higher rigidity leading to higher affinity. Moreover, by changing a few key residues, we converted mupain-1 from a uPA inhibitor to inhibitors of other serine proteases, including plasma kallikrein (PK) and coagulation factor XIa (fXIa). PK and fXIa inhibitors showed Ki values in the low nanomolar range and high specificity. Our studies demonstrate the versatility of small cyclic peptides to engineer inhibitory potency against serine proteases and to provide a new strategy for generating peptide inhibitors of serine proteases. PMID:29104489

Existence of positive periodic solution of mutualism system with several delays

International Nuclear Information System (INIS)

Wu Haihui; Xia Yonghui; Lin Muren

2008-01-01

In this paper, by using Mawhin coincidence degree, some sufficient conditions are obtained for the global existence of positive periodic solutions of a mutualism systems with bounded and unbounded delays. Our results generalize significantly improve those of Gopalsamy and He [Gopalsamy K, He XZ. Persistence, attractivity, and delay in facultative mutualism. J Math Anal Appl 1997;215:154-73], Yang et al. [Yang F, Jiang D, Ying A. Existence of positive solution of multidelays facultative mutualism system. J Eng Math 2002;3:64-8], Chen et al. [Chen FD, Shi JL, Chen XX. Periodicity in Lotka-Volterra facultative mutualism system with several delays. J Eng Math 2004;21(3)] and Xia and Lin [Xia YH, Lin M, Existence of positive periodic solution of mutualism system with infinite delays. Ann Diff Eqs 2005;21(3):448-53

QTL Information Table: 454 [Q-TARO

Lifescience Database Archive (English)

Full Text Available 61 rgn Zhuang, J.Y., Fan, Y.Y., Wu, J.L., Xia, Y.W., and Zheng, K.L. (2000). Mapping major and minor QTL for rice CMS-WA fertility restoration. Rice Genetics Newsletter 17, 56-59. ...

African Journal of Biotechnology - Vol 11, No 41 (2012)

African Journals Online (AJOL)

Lenaldo Muniz de Oliveira, Nayra da Silva Negreiros Cardoso, Luzimar Gonzaga .... Ju-Hong Zhang, Jian-Ying Guo, Jing-Yuan Xia, Fang-Hao Wan, 9873-9880 ... Zhu Xiao-yan, Chang Shu-juan, Zhang Ying-jun, Luo Hai-ling, 9894-9905.

Analysis of genetic diversity of muga silkworm (Antheraea ...

African Journals Online (AJOL)

USER

2010-03-22

Mar 22, 2010 ... Chakravorty R, Barah A, Neog K, Rahman SAS, Ghose J (2005). Package of practices ... Laboratory Manual, 2nd ed, Nolan C (ed), Cold Spring Harbor. Laboratory Press ... Sun Y, Xia N, Stapleton CMA (2005). Relationship ...

Two new genera and three new species of Epipaschiinae Meyrick from China (Lepidoptera, Pyralidae

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Mingqiang Wang

2017-12-01

Full Text Available Two new genera of Epipaschiinae are described. The genus Arcanusa Wang, Chen & Wu, gen. n. is established for Ar. apexiarcanusa Wang, Chen & Wu, sp. n. and Ar. sinuosa (Moore, 1888, comb. n., described in Scopocera Moore, 1888 (junior synonym of Stericta Lederer, 1863. The female genitalia of Ar. sinuosa (Moore, 1888, comb. n. are described for the first time. Androconia Wang, Chen & Wu, gen. n. is erected, including two new species, An. rallusa Wang, Chen & Wu, sp. n. and An. morulusa Wang, Chen & Wu, sp. n. Illustrations of all adults and their genitalia, and a key to the two new genera are provided.

The Role of SIRT1 In Breast Cancer Stem Cells

Science.gov (United States)

2016-09-01

2009;9:123-8. 56. Ma W, Xiao GG, Mao J, Lu Y, Song B, Wang L, Fan S, Fan P, Hou Z, Li J, Yu X, 20 Wang B, Wang H, Wang H, Xu F, Li Y, Liu Q, Li L...Int J Biol Sci. 2010;6:599-612. 63. Zhang Y, Zhang M, Dong H, Yong S, Li X, Olashaw N, Kruk PA, Cheng JQ, Bai W, Chen J, Nicosia SV, Zhang X

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Chemical Sciences; Volume 129; Issue 8. Three coordination compounds based on benzene tetracarboxylate ligand: syntheses, structures, thermal behaviors and luminescence properties. YUNLONG WU CHANGKUN XIA JUN QIAN JIMIN XIE. REGULAR ARTICLE Volume 129 Issue 8 August ...

Using datamining approaches to selectacupoints in acupuncture ...

African Journals Online (AJOL)

Using datamining approaches to selectacupoints in acupuncture and Moxibustion for knee osteoarthritis. Changyan Liu, Youxin Su, Jian He, Yanan Li, Shaoqing Chen, Yingjie Zhang, Ziyi Zhang, Meili Lu, Zhen He, Wenting Wang, Yiru Wang, Lu Sheng, Zhengxuan Zhan, Xu Wang, Naixi Zheng ...

Growth, yield and quality responses to gibberellic acid (GA3)of Wax ...

African Journals Online (AJOL)

Administrator

2011-09-26

Sep 26, 2011 ... acids (GAs) have been shown to increase fruit set and growth (Zabadal and ..... 350. El-Sese AMA (2005). Effect of gibberellic acid 3 (GAs) on yield and fruit ... Wang CF, You YF, Chen XS, Wang-Lu J, Wang J (2004). Adjusting.

论王安石“善恶由习”人性论的理论渊源及其内容%On the Theoretical Origins and Contents of Wang Anshi＇s Theory of Human Nature on the Good and Evil Emerged from the Habit and Custom

Institute of Scientific and Technical Information of China (English)

欧阳辉纯

2012-01-01

Traditional ethical thinking theory of human nature provided theoretical basis for Wang Anshi＇ s. The theory of human nature in traditional ethical thinking history is mainly as follows, that is, the theory advanced by Mencius that human nature is good from birth, the theory put forward by Xunzi that human nature is evil from birth, the theory put forward by Sh- ishuo that human nature is both good and evil from birth, the Sanpin theory advanced by Dong Zhongshu, the theory put for-ward by Yangxiong that human nature is mixed goodness and evilness, and the Sanpin theory of disposition advanced by Hanyu. Wang Anshi＇s theory of human nature on the good and evil emerged from the habit and custom originates from critical-ly drawing on the results of previous theory of human nature. It is to the traditional theory of human nature to inject new mean-ing, to open up new realm, and thus it has an important position in traditional ethical thinking history in China.%传统人性论是王安石人性论形成的理论来源。传统伦理思想史上的人性论主要有孟子的性善论、告子的性无善无恶论、苟子的性恶论、世硕的性有善有恶论、董仲舒的性三品论、扬雄的性善恶混论和韩愈的性情三品说。王安石批判地吸收了前人的人性论成果，形成了他的“善恶由习”的人性论。他的人性论给传统人性论注入了新的内涵，开拓了新的境界，因而在中国伦理思想史上具有重要的地位。

Supramolecular structures constructed from three novel rare earth ...

Indian Academy of Sciences (India)

Supramolecular structures constructed from three novel rare earth metal complexes. HUAZE DONGa,∗, XIAOJUN FENGb,∗, XIA LIUc, BIN ZHENGa, JIANHONG BIa, YAN XUEa,. SHAOHUA GOUd and YANPING WANGa. aDepartment of Chemistry and Chemical Engineering, Hefei Normal University, Hefei 230061, China.

Browse Title Index

African Journals Online (AJOL)

Items 201 - 250 of 449 ... Vol 65 (2012), Nano-Fe3O4/O2: Green, Magnetic and Reusable Catalytic System for the ... Vol 70 (2017), Novel silver-doped NiTiO3: auto-combustion synthesis, ... K Wang, H Wang, R Wang, J Key, V Linkov, S Ji.

Busca de estruturas em grandes escalas em altos redshifts

Science.gov (United States)

Boris, N. V.; Sodré, L., Jr.; Cypriano, E.

2003-08-01

A busca por estruturas em grandes escalas (aglomerados de galáxias, por exemplo) é um ativo tópico de pesquisas hoje em dia, pois a detecção de um único aglomerado em altos redshifts pode por vínculos fortes sobre os modelos cosmológicos. Neste projeto estamos fazendo uma busca de estruturas distantes em campos contendo pares de quasares próximos entre si em z Â3 0.9. Os pares de quasares foram extraídos do catálogo de Véron-Cetty & Véron (2001) e estão sendo observados com os telescópios: 2,2m da University of Hawaii (UH), 2,5m do Observatório de Las Campanas e com o GEMINI. Apresentamos aqui a análise preliminar de um par de quasares observado nos filtros i'(7800 Å) e z'(9500 Å) com o GEMINI. A cor (i'-z') mostrou-se útil para detectar objetos "early-type" em redshifts menores que 1.1. No estudo do par 131046+0006/J131055+0008, com redshift ~ 0.9, o uso deste método possibilitou a detecção de sete objetos candidatos a galáxias "early-type". Num mapa da distribuição projetada dos objetos para 22 escala. Um outro argumento em favor dessa hipótese é que eles obedecem uma relação do tipo Kormendy (raio equivalente X brilho superficial dentro desse raio), como a apresentada pelas galáxias elípticas em z = 0.

Production and characterization of heavy-metal removing bacterial ...

African Journals Online (AJOL)

DINESH

2012-05-17

May 17, 2012 ... heavy metal removal (Quintelas et al., 2008; Salehizadeh ..... extract and peptone (Liu et al., 2010; Nakata and Kurane,. 1999; Xia et al., 2008; Zheng et .... Banci L, Bertini I, Ciofi-Baffoni S, Su XC, Miras R, Bal N, Mintz E, Catty.

Surgical perspectives on inflammatory bowel disease

African Journals Online (AJOL)

VikasC

Xia B, Crusius JBA, Meuwissen SGM, Pena AS. Inflammatory bowel disease: Definition, epidemiology, etiologic aspects, and immunologic studies. World J. Gastroentero 1998;4:44658. 2. Fry DR, Mahmood N, Maron DJ, Ross HM, Rombeau. J. Inflammatory bowel disease in Towsend: Sabiston. Textbook of Surgery.

Photodetachment cross-section of in a three-dimensional cubical ...

Indian Academy of Sciences (India)

DE-HUA WANG

2017-10-19

Oct 19, 2017 ... DE-HUA WANG. ∗. , PANG-ZHI .... on the surfaces along x, y, z directions, respectively. Then the ..... [20] Y Han, L F Wang, S Y Ran and G C Yang, Physica B. 405, 3082 ... [36] D H Wang, Y J Yu and S L Lin, Chin. Opt. Lett.

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Genetics. LIANG WANG. Articles written in Journal of Genetics. Volume 92 Issue 3 December 2013 pp 395-402 Research Article. Association of HS6ST3 gene polymorphisms with obesity and triglycerides: gene × gender interaction · Ke-Sheng Wang Liang Wang Xuefeng Liu Min Zeng.

Proliferative Activity and Neuroprotective Effect of Ligustrazene ...

African Journals Online (AJOL)

Proliferative Activity and Neuroprotective Effect of. Ligustrazene Derivative by Irritation of Vascular. Endothelial Growth Factor Expression in Middle Cerebral. Artery Occlusion Rats. Zhang Huazheng1, Wang Penglong2, Ren Liwei1, Wang Xiaobo2, Li Guoliang2,. Wang Mina1, Chu Fuhao2, Gong Yan2, Xu Bing2, Bi Siling1, ...

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Genetics. Jinping Wang. Articles written in Journal of Genetics. Volume 91 Issue 3 December 2012 pp 303-312 Research Article. Conditional QTL mapping of protein content in wheat with respect to grain yield and its components · Lin Wang Fa Cui Jinping Wang Li Jun Anming Ding Chunhua ...

Wang Haili, The History of Egypt

Institute of Scientific and Technical Information of China (English)

Han Jianwei[1

2015-01-01

The History of Egypt is the first monograph on Egyptian history written by a single Chinese author. As a comprehensive study both in Egyptology and in Egyptian history, it represents a new level of Egyptian historical research in Chinese academia.

DONG JIE Zhang, LIANG Wang, ZHON

Indian Academy of Sciences (India)

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development, hairless nude skin, and short life (Abitbol et al., 2015; Bryson et al., 2013). On the ... Foxn1 maintains TECs to support T-cell development via mcm2 ... were ligated upstream of the firefly luciferase gene in the plasmid pGL3-Basic.

Effect of caregivers’ expressed emotion on the care burden and rehospitalization rate of schizophrenia

Directory of Open Access Journals (Sweden)

Wang X

2017-09-01

Full Text Available Xia Wang,1 Qiongni Chen,2 Min Yang1 1Xiangya School of Nursing, 2Nursing Department, Second Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of China Background: This study assessed the effect of expressed emotion (EE among caregivers of schizophrenia patients on their care burden and the illness rehospitalization rate. Subjects and methods: A total of 64 schizophrenia patients hospitalized for the first time and their key caregivers were recruited. The Chinese version of the Camberwell Family Interview (CFI-CV was used to evaluate the EE of the key caregivers. A family burden questionnaire was used to evaluate the care burden. The patients’ rehospitalization rate and medication compliance were evaluated by the self-designated criteria. The data collection was carried out at the first meeting in the hospital, at 6 months and 12 months after hospital discharge by using the same instruments. Results: The subjective stress burden and subjective demand burden scores were higher in caregivers before and after discharge with statistical difference between the various observation time points (P<0.05. Significant differences were observed in the rehospitalization rate between patients with high medication adherence and low medication adherence at 12 months (P<0.01 and between patients with high expressed emotion (HEE and low expressed emotion (LEE; P<0.05. The rehospitalization rate in patients with HEE caregivers was higher than that in those with LEE caregivers. The subjective stress burden scores were statistically significant between HEE and LEE caregivers (P<0.05.Conclusion: HEE is a predictor of rehospitalization rate in schizophrenic patients. The burdens of care scores are high in caregivers of schizophrenic patients. The caregivers with HEE have a high score in burden of care compared with those with LEE. Keywords: expressed emotion, care burden, schizophrenia, rehospitalization rate, caregivers

Mechanism Profiling of Hepatotoxicity Caused by Oxidative Stress Using Antioxidant Response Element Reporter Gene Assay Models and Big Data.

Science.gov (United States)

Kim, Marlene Thai; Huang, Ruili; Sedykh, Alexander; Wang, Wenyi; Xia, Menghang; Zhu, Hao

2016-05-01

Hepatotoxicity accounts for a substantial number of drugs being withdrawn from the market. Using traditional animal models to detect hepatotoxicity is expensive and time-consuming. Alternative in vitro methods, in particular cell-based high-throughput screening (HTS) studies, have provided the research community with a large amount of data from toxicity assays. Among the various assays used to screen potential toxicants is the antioxidant response element beta lactamase reporter gene assay (ARE-bla), which identifies chemicals that have the potential to induce oxidative stress and was used to test > 10,000 compounds from the Tox21 program. The ARE-bla computational model and HTS data from a big data source (PubChem) were used to profile environmental and pharmaceutical compounds with hepatotoxicity data. Quantitative structure-activity relationship (QSAR) models were developed based on ARE-bla data. The models predicted the potential oxidative stress response for known liver toxicants when no ARE-bla data were available. Liver toxicants were used as probe compounds to search PubChem Bioassay and generate a response profile, which contained thousands of bioassays (> 10 million data points). By ranking the in vitro-in vivo correlations (IVIVCs), the most relevant bioassay(s) related to hepatotoxicity were identified. The liver toxicants profile contained the ARE-bla and relevant PubChem assays. Potential toxicophores for well-known toxicants were created by identifying chemical features that existed only in compounds with high IVIVCs. Profiling chemical IVIVCs created an opportunity to fully explore the source-to-outcome continuum of modern experimental toxicology using cheminformatics approaches and big data sources. Kim MT, Huang R, Sedykh A, Wang W, Xia M, Zhu H. 2016. Mechanism profiling of hepatotoxicity caused by oxidative stress using antioxidant response element reporter gene assay models and big data. Environ Health Perspect 124:634-641;�

The clinical implication of serum cyclophilin A in patients with chronic obstructive pulmonary disease

Directory of Open Access Journals (Sweden)

Zhang M

2018-01-01

Full Text Available Ming Zhang,1 Jingjing Tang,1 Jiafeng Yin,2 Xiaoying Wang,3 Xiangli Feng,1 Xia Yang,1 Hu Shan,1 Qiuhong Zhang,1 Jie Zhang,1 Yali Li1 1Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, 2Department of Laboratory Examination, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, 3Health Examination Center, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China Background: Cyclophilin A (CyPA is a secreted molecule that is regulated by inflammatory stimuli. Although inflammation has an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD, little is known regarding the relationship between serum CyPA and COPD. Methods: Ninety-three COPD patients with acute exacerbation were enrolled in the study and were reassessed during the convalescence phase. Eighty-eight controls were matched for age, gender, body mass index, smoking index and comorbidity. The basic clinical information and pulmonary function of all participants were collected. Serum levels of CyPA and other inflammation indexes were further measured. Results: Serum CyPA was significantly increased in convalescent COPD patients compared to healthy controls, and further elevated in COPD patients with acute exacerbation. Serum CyPA positively correlated with serum interleukin-6, matrix metalloproteinase-9 and high-sensitivity C-reactive protein in both the exacerbation and convalescence phases of COPD. Furthermore, it negatively correlated with percent value of forced expiratory volume in 1 second (FEV1% predicted and FEV1/forced vital capacity in convalescent COPD patients. Conclusion: These results suggest that serum CyPA can be used as a potential inflammatory biomarker for COPD and assessment of serum CyPA may reflect the severity of inflammation in COPD. Keywords: cyclophilin A, chronic obstructive pulmonary disease

Downregulation of ALDOB is associated with poor prognosis of patients with gastric cancer

Directory of Open Access Journals (Sweden)

He J

2016-10-01

Full Text Available Jun He,1 Yi Jin,1 Yuan Chen,2 Hai-Bo Yao,1 Ying-Jie Xia,3 Ying-Yu Ma,4 Wei Wang,2 Qin-Shu Shao1 1Department of Gastroenterology and Pancreatic Surgery, 2Department of Pathology, 3Key Laboratory of Gastroenterology of Zhejiang Province, 4Clinic Research Institute, Zhejiang Provincial People’s Hospital, Hangzhou, People’s Republic of China Objectives: To examine the expression of ALDOB in gastric cancer (GC tissue and to reveal its potential clinicopathological and prognostic significance.Materials and methods: We screened for genes that were differentially expressed between GC and nontumor tissues using a microarray, specifically the Affymetrix U133 Plus 2.0 Array platform. We then verified the transcriptional and translational levels of ALDOB by performing quantitative real-time polymerase chain reaction (qRT-PCR and immunohistochemistry (IHC. In addition, a merged data set based on the Gene Expression Omnibus was generated and a survival analysis performed.Results: The microarray analysis revealed that ALDOB was downregulated (more than sevenfold in GC compared with nontumor tissue. Both qRT-PCR and IHC validated the decrease of ALDOB in GC tissue. Moreover, we found that the expression of ALDOB was significantly related to tumor-invasion depth, lymph-node metastasis, distant metastasis, and TNM stage. The survival analysis, based on the IHC and merged data set, indicated that the overall survival was better in patients with high ALDOB expression. The Cox regression analysis showed that ALDOB expression was an independent prognostic factor for GC.Conclusion: The expression of ALDOB in GC tissue was significantly related to the clinicopathological features and prognosis of the disease, thus suggesting that ALDOB could act as a novel molecular marker for GC. Keywords: ALDOB, gastric cancer, microarray analysis, molecular marker

Injectable hydrogel as stem cell scaffolds from the thermosensitive terpolymer of NIPAAm/AAc/HEMAPCL

Directory of Open Access Journals (Sweden)

Lian S

2012-09-01

Full Text Available Sheng Lian,1Yan Xiao,1 Qingqing Bian,1Yu Xia,2 Changfa Guo,2 Shenguo Wang,2 Meidong Lang11Shanghai Key Laboratory of Advanced Polymeric Materials, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, People's Republic of China; 2Department of Cardiac Surgery, Zhongshan Hospital, Fudan University and Shanghai Institute of Cardiovascular Diseases, Shanghai, People's Republic of ChinaAbstract: A series of biodegradable thermosensitive copolymers was synthesized by free radical polymerization with N-isopropylacrylamide (NIPAAm, acrylic acid (AAc and macromer 2-hydroxylethyl methacrylate-poly(ε-caprolactone (HEMAPCL. The structure and composition of the obtained terpolymers were confirmed by proton nuclear magnetic resonance spectroscopy, while their molecular weight was measured using gel permeation chromatography. The copolymers were dissolved in phosphate-buffered saline (PBS solution (pH = 7.4 with different concentrations to prepare hydrogels. The lower critical solution temperature (LCST, cloud point, and rheological property of the hydrogels were determined by differential scanning calorimetry, ultraviolet-visible spectrometry, and rotational rheometry, respectively. It was found that LCST of the hydrogel increased significantly with the increasing NIPAAm content, and hydrogel with higher AAc/HEMAPCL ratio exhibited better storage modulus, water content, and injectability. The hydrogels were formed by maintaining the copolymer solution at 37°C. The degradation experiment on the formed hydrogels was conducted in PBS solution for 2 weeks and demonstrated a less than 20% weight loss. Scanning electron microscopy was also used to study the morphology of the hydrogel. The copolymer with NIPAAm/AAc/HEMAPCL ratio of 88:9.6:2.4 was bioconjugated with type I collagen for the purpose of biocompatibility enhancement. In-vitro cytotoxicity

Gene therapy for C-26 colon cancer using heparin-polyethyleneimine nanoparticle-mediated survivin T34A

Directory of Open Access Journals (Sweden)

Zhang L

2011-10-01

Full Text Available Ling Zhang1,*, Xiang Gao1,2,*, Ke Men1, BiLan Wang1, Shuang Zhang1, Jinfeng Qiu1, Meijuan Huang1, MaLing Gou1, Ning Huang2, ZhiYong Qian1, Xia Zhao1, YuQuan Wei11State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, 2Department of Pathophysiology, College of Preclinical and Forensic Medical Sciences, Sichuan University, Chengdu, People’s Republic of China*These authors contributed equally to this workBackground: Gene therapy provides a novel method for the prevention and treatment of cancer, but the clinical application of gene therapy is restricted, mainly because of the absence of an efficient and safe gene delivery system. Recently, we developed a novel nonviral gene carrier, ie, heparin-polyethyleneimine (HPEI nanoparticles for this purpose.Methods and results: HPEI nanoparticles were used to deliver plasmid-expressing mouse survivin-T34A (ms-T34A to treat C-26 carcinoma in vitro and in vivo. According to the in vitro studies, HPEI nanoparticles could efficiently transfect the pGFP report gene into C-26 cells, with a transfection efficiency of 30.5% ± 2%. Moreover, HPEI nanoparticle-mediated ms-T34A could efficiently inhibit the proliferation of C-26 cells by induction of apoptosis in vitro. Based on the in vivo studies, HPEI nanoparticles could transfect the Lac-Z report gene into C-26 cells in vivo. Intratumoral injection of HPEI nanoparticle-mediated ms-T34A significantly inhibited growth of subcutaneous C-26 carcinoma in vivo by induction of apoptosis and inhibition of angiogenesis.Conclusion: This research suggests that HPEI nanoparticle-mediated ms-T34A may have a promising role in C-26 colon carcinoma therapy.Keywords: gene therapy, mouse survivin-T34A, colon cancer, polyethyleneimine, nanoparticles, cancer therapy

Expression of MMP-1/PAR-1 and patterns of invasion in oral squamous cell carcinoma as potential prognostic markers

Directory of Open Access Journals (Sweden)

Fan HX

2015-07-01

Full Text Available Hai-Xia Fan,1 Yan Chen,1 Bo-Xiong Ni,1 Shan Wang,1 Miao Sun,2 Dong Chen,2 Jin-Hua Zheng11Department of Anatomy, Basic Medical Science College, 2Department of Oral and Maxillofacial Surgery, Stomatological Hospital, Harbin Medical University, Harbin, People’s Republic of ChinaBackground: Matrix metalloproteinase (MMP-1 degrades type I collagen of the extracellular matrix and also activates protease activated receptor (PAR-1 to induce angiogenesis. The aims of this study were to evaluate microvessel density (MVD and the expression of PAR-1 and MMP-1 in oral squamous cell carcinoma (SCC specimens with different patterns of invasion (POI and to evaluate their association with clinical outcomes.Methods: Seventy-four surgically obtained oral SCC samples were classified by POI according to hematoxylin-eosin staining. MVD and the localization and intensity of PAR-1 and MMP-1 expression were detected by immunohistochemistry.Results: Of the 74 oral SCC samples, 18, 5, 34, and 17 showed type I, II, III, and IV POI, respectively. MVD and expression levels of MMP-1 and PAR-1 differed between POI types I–II and POI types III–IV. Patients with low tumor expression of MMP-1 and PAR-1 and low MVD had a longer survival time than those with high tumor expression of MMP-1 and PAR-1. Moreover, the survival time of patients with POI types III–IV was shorter than that of patients with POI types I–II.Conclusion: POI combined with expression levels of MMP-1 and PAR-1 may be a valuable tool for assessing the clinical prognosis of patients with oral SCC.Keywords: oral squamous cell carcinoma, pattern of invasion, immunohistochemistry, clinical outcomes

Combination therapy of fenofibrate and ursodeoxycholic acid in patients with primary biliary cirrhosis who respond incompletely to UDCA monotherapy: a meta-analysis

Directory of Open Access Journals (Sweden)

Zhang Y

2015-05-01

Full Text Available Yan Zhang,1,2,* Sainan Li,1,* Lei He,1 Fan Wang,1 Kan Chen,1 Jingjing Li,1 Tong Liu,1 Yuanyuan Zheng,1 Jianrong Wang,1,3 Wenxia Lu,1,3 Yuqing Zhou,1,4 Qin Yin,1,4 Yujing Xia,1 Yingqun Zhou,1 Jie Lu,1 Chuanyong Guo1 1Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 2Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 3The First Clinical Medical College of Nanjing Medical University, Nanjing, 4The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China *These authors contributed equally to this work Background: Although the effectiveness of treatment with ursodeoxycholic acid (UDCA and fenofibrate for primary biliary cirrhosis (PBC has been suggested by small trials, a systematic review to summarize the evidence has not yet been carried out.Methods: A meta-analysis of all long-term randomized controlled trials comparing the combination of UDCA and fenofibrate with UDCA monotherapy was performed via electronic searches.Results: Six trials, which included 84 patients, were assessed. Combination therapy with UDCA and fenofibrate was more effective than UDCA monotherapy in improving alkaline phosphatase (mean difference [MD]: -90.44 IU/L; 95% confidence interval [CI]: -119.95 to -60.92; P<0.00001, gamma-glutamyl transferase (MD: -61.58 IU/L; 95% CI: -122.80 to -0.35; P=0.05, immunoglobulin M (MD: -38.45 mg/dL; 95% CI: -64.38 to -12.51; P=0.004, and triglycerides (MD: -0.41 mg/dL; 95% CI: -0.82 to -0.01; P=0.05. However, their effects on pruritus (odds ratio [OR]: 0.39; 95% CI: 0.09–1.78; P=0.23, total bilirubin (MD: -0.05 mg/dL; 95% CI: -0.21 to 0.12; P=0.58, and alanine aminotransferase (MD: -3.31 IU/L; 95% CI: -14.60 to 7.97; P=0.56 did not differ significantly. This meta-analysis revealed no significant differences in the incidence of adverse events (OR: 0.21; 95% CI: 0.03–1.25; P=0.09 between patients treated with

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Genetics. YANG LUO. Articles written in Journal of Genetics. Volume 90 Issue 2 August 2011 pp 339-342 Research Note. Novel vitamin D 1-hydroxylase gene mutations in a Chinese vitamin-D-dependent rickets type I patient · Lihua Cao Fang Liu Yu Wang Jian Ma Shusen Wang Libo Wang ...

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Conditional QTL mapping of protein content in wheat with respect to grain yield and its components · Lin Wang Fa Cui Jinping Wang Li Jun ... The association study of nonsyndromic cleft lip with or without cleft palate identified risk variants of the GLI3 gene in a Chinese population · YIRUI WANG YIMIN SUN YONGQING ...

Resource-Bounded Information Acquisition and Learning

Science.gov (United States)

2012-05-01

Different combinations of voting and confidence evaluation schemes...H. Wang, ... Facial Expression Decomposition..., ICCV, 2003. (E)..., H. Wang, ... Tensor Approximation..., SIGGRAPH. 2005. (F)..., H. Wang, ... High...two of the possible schemes for combining the evidence in the output space. In the first scheme, we take a majority 67 vote , i.e., the class with the

HOTEL INFORMATION

Institute of Scientific and Technical Information of China (English)

无

2006-01-01

Tiantan Hotel Wang Ping has been named as assistant general manager of Tiantan Hotel. With a Master's degree, Wang has more than 20 years of experience in hotel management, having served as department manager, assistant general manager and vice general manager in various hospitality establishments. Wang published an article on hotel management and mar-

Browse Title Index

African Journals Online (AJOL)

Items 501 - 550 of 1309 ... HH Tamboura, B Bayala, M Lompo, IP Guissou, L Sawadogo ... X Wang, Y-G Chen, L Ma, Z-H Li, J-Y Li, X-G Liu, J-L Zou, J-H Wu. Vol 11, No 2 ... Zhi-Jiang Wang, Wei Xu, Jian-Wen Liang, Cai-Sheng Wang, Yani Kang.

Verification of the utility of molecular markers linked to the multiple ...

African Journals Online (AJOL)

GREGORY

2010-08-30

Aug 30, 2010 ... Feng Hui*, Wang Lili, Wei Peng, Liu Zhiyong, Li Chengyu, Wang Yugang, Ji Ruiqin and Zhang. Huaqing ..... Chin. Agric. Sci. Bull. 22: 377-379. Li CY, Feng H, Wei P, Wang LL, Zhang J, Yang HN, Jiang N (2009). Directional transfer of the genic multiple allele inherited male sterile line in Chinese cabbage.

Antioxidant and Anti-proliferative Activities of Flavonoids from ...

African Journals Online (AJOL)

significant growth inhibitory effect on RKO cells with IC50 of 39.08 μmol/L and 17.68 μmol/L, respectively ..... YJ.. Essential oil from rhizomes of Ligusticum chuanxiong induces apoptosis in hypertrophic scar ... Liu H, Mou Y, Zhao J, Wang J, Zhou L, Wang M, Wang. D, Han J, Yu Z, Yang F. Flavonoids from Halostachys.

F F Sun

Indian Academy of Sciences (India)

Home; Journals; Bulletin of Materials Science. F F Sun. Articles written in Bulletin of Materials Science. Volume 37 Issue 1 February 2014 pp 71-76. Study of electroless copper plating on ABS resin surface modified by heterocyclic organosilane self-assembled film · H N Zhang J Wang F F Sun D Liu H Y Wang F Wang.

AHP 40: Review: CHINA FROM EMPIRE TO NATION-STATE

Directory of Open Access Journals (Sweden)

Tristan G Brown

2016-02-01

Full Text Available Michael Gibbs Hill's excellent translation of the introduction to Wang Hui's four-volume opus, The Rise of Modern Chinese Thought 现代中 国思想的兴起 provides a substantial contribution to scholars of China and intellectual historians by bringing another of Wang Hui's critical works into English (for other such examples, see Wang and Huters 2003 and 2011. The task of translating could not have been easy, as Wang Hui frequently cites works from Chinese antiquity and translated texts from abroad, making Hill's results truly exceptional. The translation is accessible and painstakingly executed, with many important phrases explained for non-specialists alongside transliterated key terms. The Rise of Modern Chinese Thought demonstrates the need for translation work in the fields of area studies by making the important works of non-English speakers available to Anglophone audiences. As Zhang Yongle pointed out in his review on the work in toto, "It can safely be said that nothing comparable to Wang Hui's work has appeared in China since the late Qing-early Republican period" (Zhang 2010:71. Wang Hui, while exploring the links between China and its past through the country's rich intellectual traditions, manages to deftly discuss China in global terms and historical contexts. Hill's helpful introduction contextualizes Wang's writing style in the zeitgeist of the post Tiananmen period from 1990 to 2010. ...

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Genetics. ZHONGJIE CHANG. Articles written in Journal of Genetics. Volume 89 Issue 2 August 2010 pp 183-192 Research Article. cDNA cloning and expression analysis of two distinct Sox8 genes in Paramisgurnus dabryanus (Cypriniformes) · Xiaohua Xia Jie Zhao Qiyan Du Zhongjie Chang.

A role for stomata in regulating water use efficiency in Populus x ...

African Journals Online (AJOL)

A role for stomata in regulating water use efficiency in Populus x euramericana and characterization of a related gene, PdERECTA. P Guo, X Xia, WL Yin. Abstract. The physiological mechanism of water use efficiency (WUE) remains elucidated, especially in poplar. We studied WUEi (instantaneous leaf transpiration ...

Effect of Scopoletin on Apoptosis and Cell Cycle Arrest in Human ...

African Journals Online (AJOL)

treatment with increasing doses compared to control cells, scopoletin treatment resulted in cell ... Conclusion: These results reveal that scopoletin may be used as a natural chemotherapeutic agent .... apoptosis, and necrosis in LNCaP cells .... Pan R, Dai Y, Gao XH, Lu D, Xia YF. Inhibition of vascular endothelial growth.

Earth fissures in Qinglong Graben in Yuncheng Basin, China

Indian Academy of Sciences (India)

Jianwei Qiao

2018-02-14

Feb 14, 2018 ... Key Laboratory of Western China Mineral Resources and Geological Engineering, Xi'an 710 054, Shaanxi, China. *Corresponding .... first to appear in edge and then extended to the center. ..... Miao D Y, Li Y L, Lv S H, Tian J M, Wang Y R and Si ... Wang J M, Wang C M and Liu K 2001 Progress in ground.

Browse Title Index

African Journals Online (AJOL)

Items 7351 - 7400 of 11090 ... Vol 10, No 65 (2011), Molecular cloning and sequence analysis of VP6 gene of giant panda rotavirus strain CH-1, Abstract PDF. Y Lie, S Chen, CD Wang, Z Zhang, CD Wang, W Guo, X Wang, L Guo, Q Yan. Vol 11, No 23 (2012), Molecular cloning, characterization and expression analysis of heat ...

WE-C-TOUR-I-01: Dosimters for QC in Diagnostic Imaging

International Nuclear Information System (INIS)

Jiang, X.

2016-01-01

Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Adrien Sanchez, University of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

WE-C-TOUR-I-00: Exhibit Hall Guided Tours-Dosimters for QC in Diagnostic Imaging (Wednesday)

International Nuclear Information System (INIS)

2016-01-01

Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Adrien Sanchez, University of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

TU-E-TOUR-I-00: Exhibit Hall Guided Tours-Dosimters for QC in Diagnostic Imaging (Tuesday)

International Nuclear Information System (INIS)

2016-01-01

Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Christina Sammet, Lurie Children’s Hospital of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

WE-C-TOUR-I-00: Exhibit Hall Guided Tours-Dosimters for QC in Diagnostic Imaging (Wednesday)

Energy Technology Data Exchange (ETDEWEB)

NONE

2016-06-15

Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Adrien Sanchez, University of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

WE-C-TOUR-I-01: Dosimters for QC in Diagnostic Imaging

Energy Technology Data Exchange (ETDEWEB)

Jiang, X. [Ohio State University (United States)

2016-06-15

Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Adrien Sanchez, University of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

TU-E-TOUR-I-00: Exhibit Hall Guided Tours-Dosimters for QC in Diagnostic Imaging (Tuesday)

Energy Technology Data Exchange (ETDEWEB)

NONE

2016-06-15

Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Christina Sammet, Lurie Children’s Hospital of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.

Epigenetic game theory and its application in plants. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

Science.gov (United States)

Zhang, Yuan-Ming; Zhang, Yinghao; Guo, Mingyue

2017-03-01

Wang's et al. article [1] is the first to integrate game theory (especially evolutionary game theory) with epigenetic modification of zygotic genomes. They described and assessed a modeling framework based on evolutionary game theory to quantify, how sperms and oocytes interact through epigenetic processes, to determine embryo development. They also studied the internal mechanisms for normal embryo development: 1) evolutionary interactions between DNA methylation of the paternal and maternal genomes, and 2) the application of game theory to formulate and quantify how different genes compete or cooperate to regulate embryogenesis through methylation. Although it is not very comprehensive and profound regarding game theory modeling, this article bridges the gap between evolutionary game theory and the epigenetic control of embryo development by powerful ordinary differential equations (ODEs). The epiGame framework includes four aspects: 1) characterizing how epigenetic game theory works by the strategy matrix, in which the pattern and relative magnitude of the methylation effects on embryogenesis, are described by the cooperation and competition mechanisms, 2) quantifying the game that the direction and degree of P-M interactions over embryo development can be explained by the sign and magnitude of interaction parameters in model (2), 3) modeling epigenetic interactions within the morula, especially for two coupled nonlinear ODEs, with explicit functions in model (4), which provide a good fit to the observed data for the two sexes (adjusted R2 = 0.956), and 4) revealing multifactorial interactions in embryogenesis from the coupled ODEs in model (2) to triplet ODEs in model (6). Clearly, this article extends game theory from evolutionary game theory to epigenetic game theory.

Rastrelliger systematics inferred from mitochondrial cytochrome b ...

African Journals Online (AJOL)

USER

2010-05-24

May 24, 2010 ... were selected as outgroups to root the phylogenetic trees. All sequences were viewed, edited and aligned using MEGA version 4 software (Tamura et al., 2007). Substitution saturation tests were performed using DAMBE (Xia and Xie, 2001) by plotting the number of observed transitions (Ti) relative to that ...

New Horizons in Education, 2003.

Science.gov (United States)

Ho, Kwok Keung, Ed.

2003-01-01

This journal, written in English and Chinese, includes the following papers: "Values for Creativity: A Study among Undergraduates in Hong Kong and Guangzhou" (Xia Dong Yue and Kok Leung); "The Present Situation of Family Education at the Turn of the Century: An Investigation in Three South-Eastern Provinces in China" (Feng…

Saturation mapping of QTL region determining resistance specificity ...

African Journals Online (AJOL)

STORAGESEVER

2009-09-01

Sep 1, 2009 ... S, Ni L, Zhu F, Chen W, Lan L, Lai Y, Cheng Z, Gu M, Jiang J, Li J,. Hong G, Xue Y, Han B ... Katagiri F, Markus Lange B, Moughamer T, Xia Y, Budworth P,. Zhong J, Miguel T, ... Gen. Genet. 261: 58-63. Marrs KA (1996).

Characterization of 2PA Chromophores

Science.gov (United States)

2016-01-01

When performing perturbation theory to calculate two-photon absorption, it is the product of one-photon absorption matrix elements (proportional to...vol. 2, pp. 1776-1790, 2012. [29] T. Xia, D. J. Hagan, M. Sheik-Bahae, and E. W. Van Stryland, "Eclipsing Z-Scan Measurement of ( lambda /10^4

A Study on Expression and Tyrosine 705 phosphorylation of STAT3 ...

African Journals Online (AJOL)

Fas- and Bcl-2-positive cells counts on the one hand, and apoptosis-positive nerve cells count in IP and. IC, on the ..... Chen Z, Li L, Mo X, Zhang L, Xie Y, Guo Q, Wang Y. Non-invasive ... Du W, Hong J, Wang YC, Zhang YJ, Wang P, Su YW,. Lin YW, Lu R, ... Jo M, Park MH, Kollipara PS, An BJ, Song HS, Han SB,. Kim JH ...

Variation of photosynthetic tolerance of rice cultivars (Oryza sativa L ...

African Journals Online (AJOL)

STORAGESEVER

2010-03-01

Mar 1, 2010 ... (Oryza sativa L.) to chilling temperature in the light. Xia Li*, Kun Cao, Chao .... 2 mol) formed red-brown trimethine that can be detected quantitatively with spectrophoto- ..... ses through the generation of appropriate signals (H2O2) and the balance ..... was under weak light intensity (Murata, 1989). Light.

Reference: 759 [Arabidopsis Phenome Database[Archive

Lifescience Database Archive (English)

Full Text Available 759 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u18434608i Guan Yue-Feng...s. 2 852-63 18434608 2008 Jun Plant physiology Gao Ju-Fang|Guan Yue-Feng|Huang Xue-Yong|Yang Zhong-Nan|Zhang Hong-Xia|Zhu Jun

Guangdong Aluminum to Raise RMB 3 billion for New Production Base in Guizhou

Institute of Scientific and Technical Information of China (English)

2010-01-01

<正>On July 7, a loan signing ceremony was held between the Guangdong Aluminum Group, China Construction Bank, Hua Xia Bank and Guangzhou Bank Consortium. It is reported that these banks will provide Guangdong Aluminum Group with RMB 30 billion for an alu-minum oxide and supporting bauxite mining project in Guizhou.

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Chemical Sciences. Chen Chai. Articles written in Journal of Chemical Sciences. Volume 126 Issue 3 May 2014 pp 813-820 Regular Articles. First total synthesis of Boehmenan · Yamu Xia Xiaoli Dai Haixin Liu Chen Chai · More Details Abstract Fulltext PDF. The first total synthesis of dilignan ...

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African Journals Online (AJOL)

Dan Jiang 1*, Jian-Hong Zhou 2*, Jue Zhou 3 , Ying-Er Gu 2, Dong-Xia Yang 4, Qing .... Women were informed about the short- and long-term benefits of HRT. .... Current employment status .... randomized, double-blind, controlled trial of a Chinese herbal formula (Er-Xian decoction) for menopausal symptoms in Hong Kong.

Physiological response of American bullfrog tadpoles to stressor conditions of capture and hypoxia Resposta fisiológica de girinos de rã-touro americana submetidos aos mecanismos estressores de captura e hipóxia.

Directory of Open Access Journals (Sweden)

Guilherme C Rocha

2010-10-01

girinos de rã-touro submetidos aos mecanismos estressores de captura e hipóxia. Os animais foram distribuídosem três tratamentos: estresse por captura individual com puçá; estresse por captura em massa com puçá e estresse por captura por escoamento. Os resultados obtidos demostraram não haver diferenças estatisticamente significativas entre os parametros avaliados quando comparou-se os grupos com e sem exposição ao ar (normoxia e hipoxia. Com base nestes resultados pode-se concluir que os estímulos estressores avaliados não foram adequados para alterar os valores plasmáticos dos marcadores biológicos testados. Para o cortisol, isto ocorreu provavelmente em virtude da ação sinérgica deste hormônio e a tiroxina, que induz a metamorfose nestes animais.

Hybrid Chaos Synchronization of Four-Scroll Systems via Active Control

Science.gov (United States)

Karthikeyan, Rajagopal; Sundarapandian, Vaidyanathan

2014-03-01

This paper investigates the hybrid chaos synchronization of identical Wang four-scroll systems (Wang, 2009), identical Liu-Chen four-scroll systems (Liu and Chen, 2004) and non-identical Wang and Liu-Chen four-scroll systems. Active control method is the method adopted to achieve the hybrid chaos synchronization of the four-scroll chaotic systems addressed in this paper and our synchronization results are established using Lyapunov stability theory. Since the Lyapunov exponents are not required for these calculations, the active control method is effective and convenient to hybrid synchronize identical and different Wang and Liu-Chen four-scroll chaotic systems. Numerical simulations are also shown to illustrate and validate the hybrid synchronization results derived in this paper.

New Jurassic tettigarctid cicadas from China with a novel example of disruptive coloration

Directory of Open Access Journals (Sweden)

Jun Chen

2016-12-01

Full Text Available Tettigarctidae is the most primitive family of Cicadoidea, with only two relict species. Although they are relatively well known from Eurasia, Australia, Africa, and South America, their Mesozoic examples are typically preserved only as isolated forewings. Herein, a new genus Sanmai Chen, Zhang, and B. Wang with three new species (Sanmai kongi Chen, Zhang, and B. Wang, S. mengi Chen, Zhang, and B. Wang, and S. xuni Chen, Zhang, and B. Wang are described based on fossil specimens from the Middle–Upper Jurassic of northeastern China, with well-preserved body structures, forewing and hindwing venations, making it the hitherto best known extinct tettigarctid taxon. The new genus, provisionally assigned to the tribe Turutanoviini, provides some new information about the evolution and palaeobiogeography of Mesozoic Tettigarctidae. The genus Paraprosbole is synonymized with Shuraboprosbole. In addition, the coloration pattern of forewing, prominent on some specimens of Sanmai kongi Chen, Zhang, and B. Wang sp. nov. and Sanmai xuni Chen, Zhang, and B. Wang sp. nov., represents a novel example of disruptive coloration in Tettigarctidae, which can effectively break up the body outline as well as surface, and so likely enabled these cicadas to reduce the detectability of potential predators.

Cone-beam computed tomography study of the root and canal morphology of mandibular permanent anterior teeth in a Chongqing population [Corrigendum

Directory of Open Access Journals (Sweden)

Yang ZY

2016-03-01

Full Text Available Zhengyan Yang, Keke Lu, Fei Wang, Yueheng Li, Zhi ZhouDepartment of Preventive Dentistry, The College of Stomatology, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing, People’s Republic of ChinaOn page 19, the author’s names were listed incorrectly as Yang Zhengyan, Lu Keke, Wang Fei, Li Yueheng, Zhou Zhi.The correct names are Zhengyan Yang, Keke Lu, Fei Wang, Yueheng Li, Zhi Zhou.View the original paper here.

Consumer evaluation of imported organic food products in emerging economies in Asia

OpenAIRE

Pedersen, Susanne; Aschemann-Witzel, Jessica; Thøgersen, John

2017-01-01

Consumer evaluation of imported organic food products in emerging economies in Asia Introduction Consumers in emerging economies such as Thailand and China have started to demand organic food products – mainly due to food safety reasons (Ortega, Wang, Wu, & Hong, 2015; Roitner-Schobesberger, Darnhofer, Somsook, & Vogl, 2008; C. L. Wang, Li, Barnes, & Ahn, 2012; O. Wang, De Steur, Gellynck, & Verbeke, 2015). However, since the domestic organic markets are still not well-establi...

A condição de altitude simulada piora o estado de humor e aumenta a pressão arterial sistólica de jovens saudáveis

Directory of Open Access Journals (Sweden)

Jorge Fernando Tavares de Souza

2016-03-01

Full Text Available A literatura aponta que o estresse do ambiente aliado ao estresse do exercício físico produz alterações psicológicas e fisiológicas. Portanto, o objetivo do presente estudo foi investigar a associação entre o efeito agudo do exercício físico moderado realizado em condição de atitude simulada sobre o estado de humor, saturação da oxihemoglobina e pressão arterial de jovens saudáveis. Dez voluntários realizaram 45 min. de exercício físico e passaram por duas condições: Condição Normóxia (CN e Condição Hipóxia (CH. Em ambas as condições eles responderam a dois instrumentos que avaliam as respostas de humor, a Escala de Humor de Brunel (BRUMS e a Escala Subjetiva de Experiência em Exercício (SEES, bem como a avaliação da saturação de oxihemoglobina e da pressão arterial. Esses procedimentos foram realizados antes, imediatamente após, 30 min. e 60 min. após o término do protocolo. Após a prática do exercício físico na Condição Hipóxia, os voluntários apresentaram maiores escores de Fadiga, Confusão Mental, DTH, Raiva, Distresse Psicológico e menores valores de Vigor e Bem-Estar Positivo acompanhados de uma diminuição da saturação da oxihemoglobina. O exercício físico moderado realizado em altitude simulada de 4500m promove mudanças no estado de humor e aumento da pressão arterial sistólica de jovens saudáveis.

A fonte ionizante do disco de acreção no núcleo de NGC1097

Science.gov (United States)

Silva, R. N.; Storchi-Bergmann, T.

2003-08-01

Observações em raios-X revelam o "coração" dos núcleos ativos de galáxias, pois esse tipo de radiação provém das suas regiões mais internas, próximas ao buraco negro central. Neste trabalho apresentamos observações em raios-X da região central da galáxia NGC1097, que hospeda um buraco negro supermassivo e um disco de acreção cuja emissão vem sendo observada há dez anos através da linha de emissão Ha larga (10000 km/s) e de duplo pico. As observações em raios-X - que foram obtidas com o Telescópio Chandra - foram combinadas com observações no ultravioleta obtidas com o Telescópio Espacial Hubble e são usadas para estudar as características da fonte central que ioniza o disco de acreção. A distribuição espectral de energia é comparada com a predita por modelos, em particular o de uma estrutura "ADAF" ("advection dominated accretion flow") na parte interna do disco. Tal estrutura produz um espectro de emissão de linhas estreitas tipo LINER, como observado em NGC1097 e em rádio-galáxias que apresentam linhas de Balmer largas de duplo pico. Apresentamos também uma comparação entre outros LINERs com linhas de emissão largas de duplo pico, disponíveis na literatura ou nos arquivos do Chandra e do Telescópio Espacial Hubble e discutimos as correspondentes implicações para modelos da fonte central.

Tempêtes sanglantes sur les hautes terres tibétaines

OpenAIRE

Jie, Yu

2011-01-01

Woeser (Wei Se), Sha jie. Sishi nian de jiyi jinqu. Jingtou xia de Xizang wenhua. Di yi ci gongkai. (Massacres et pillages. Mémoire interdite depuis 40 ans. La culture tibétaine sous un objectif pour la première fois) Forbidden memory. Tibet during the Cultural Revolution, Taipei, Dakuai wenhua, 2006, 296 p.

Role of IKK-alpha in the EGFR Signaling Regulation

Science.gov (United States)

2014-09-01

expression. (E) Kaplan -Meier overall survival curves of IKKin breast cancer patient data set. 16 Reference 1. Lo, H. W., Xia, W., Wei, Y...150- 100- 50- 150- 100- Twist1 AKT1-p AKT-T C 250- 150- 100- N-cad P1 P2 P3 TGFβ - - - + + - + + - - + - - + + + - - + - - + + + 50- Vimentin 150- 100

A new approximate algorithm for image reconstruction in cone-beam spiral CT at small cone-angles

International Nuclear Information System (INIS)

Schaller, S.; Flohr, T.; Steffen, P.

1996-01-01

This paper presents a new approximate algorithm for image reconstruction with cone-beam spiral CT data at relatively small cone-angles. Based on the algorithm of Wang et al., our method combines a special complementary interpolation with filtered backprojection. The presented algorithm has three main advantages over Wang's algorithm: (1) It overcomes the pitch limitation of Wang's algorithm. (2) It significantly improves z-resolution when suitable sampling schemes are applied. (3) It avoids the waste of applied radiation dose inherent to Wang's algorithm. Usage of the total applied dose is an important requirement in medical imaging. Our method has been implemented on a standard workstation. Reconstructions of computer-simulated data of different phantoms, assuming sampling conditions and image quality requirements typical to medical CT, show encouraging results

Integrated bioinformatic analysis unveils significant genes and pathways in the pathogenesis of supratentorial primitive neuroectodermal tumor

OpenAIRE

Wang,Guang-Yu; Li,Ling; Liu,Bo; Han,Xiao; Wang,Chunhua; Wang,Jiwen

2018-01-01

Guang-Yu Wang,1,* Ling Li,2,* Bo Liu,1 Xiao Han,1 Chun-Hua Wang,1 Ji-Wen Wang3 1Department of Neurosurgery, 2Department of Pediatrics, Qilu Children’s Hospital of Shandong University, Jinan, Shandong, 3Department of Neurology, Shanghai Children’s Medical Center, Shanghai Jiaotong University School of Medicine, Pudong New District, Shanghai, People’s Republic of China *These authors contributed equally to this work Purpose: This study aimed to explore ...

Integrated bioinformatic analysis unveils significant genes and pathways in the pathogenesis of supratentorial primitive neuroectodermal tumor

OpenAIRE

Wang G; Li L; Liu B; Han X; Wang CH; Wang JW

2018-01-01

Guang-Yu Wang,1,* Ling Li,2,* Bo Liu,1 Xiao Han,1 Chun-Hua Wang,1 Ji-Wen Wang3 1Department of Neurosurgery, 2Department of Pediatrics, Qilu Children’s Hospital of Shandong University, Jinan, Shandong, 3Department of Neurology, Shanghai Children’s Medical Center, Shanghai Jiaotong University School of Medicine, Pudong New District, Shanghai, People’s Republic of China *These authors contributed equally to this work Purpose: This study aimed to explore significant gene...

Reforming China’s Criminal Procedure Law

OpenAIRE

Winckler, Hugo

2014-01-01

Sources:- Wang Jianxun, “The provisions of the reform of criminal procedural law legalising secret investigations are a step backwards,” Caijing wang, 5 September 2011.- Chen Youxi, “The legalisation of secret investigations is an important violation of political integrity,” Zhongguo wangluo dianshitai – CNTV web site, Opinion section, 27 November 2011.- Wu Zhehua, “Chen Weidong discusses reform of the criminal procedure law: Behind each article there is a story,” Zhongguoguangbo wang, 8 Marc...

Untitled

Indian Academy of Sciences (India)

Proc. of ICEM-1992, Budapest, pp 550-553. 23) A R Millner 1994 Multi-hundred horsepower permanent magnet brushless disk motors. Proc. of APEC Conf, pp 351-355 w. (24 C C Chen, KT Chau, J ZJiang, W Xia, M. Zhu, R. Zhang 1996 Novel permanent magnet motor drives for electric vehicles. IEEE Trans. Ind. Electron.

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Genetics; Volume 90; Online resources. Genotyping of the k-casein and -lactoglobulin genes in Chinese Holstein, Jersey and water buffalo by PCR-RFLP. Da-Xi Ren Shu-Ying Miao You-Liang Chen Cai-Xia Zou Xian-Wei Liang Jian-Xin Liu. Volume 90 Online resources 2011 pp e1-e5 ...

Wide Band Gap Semiconductors Symposium Held in Boston, Massachusetts on 2-6 December 1991. Materials Research Society Symposium Proceedings. Volume 242

Science.gov (United States)

1992-01-01

AND PROPERTIES OF WIDE BAND-GAP Il-VI STRAINED- LAYER SUPERLATTICE 227 Hailong Wang. Jie Cui. Aidong Shen. Liang Xu, Yunliang Chen. and Yuhua Shen IN...WANG JIE CUI AIDONG SHEN LIANG XU YUNLIANG CHEN AND YUHUA SHEN Shanghai Institute of Optics and Fine Mechanics, Academia Sinica P.O.Box 800-216 Shanghai...He Zujou, Cao Huazhe, Su Wuda, Chen Zhongcai, Zhon Feng and Wang Erguang, Thin Solid Films, 139,261(1986). 22) Xin Li and T.L.Tansley, J.AppI.Phys

The Role of Retinal Determination Gene Network (RDGN) in Hormone Signaling Transduction and Prostate Tumorigenes

Science.gov (United States)

2015-12-01

S, Zhang W, Zhou J, Wang J, Ertel A, Li Z, Rui H, Quong A, Lisanti MP, Tozeren A, Tanes C, Addya S, Gormley M, Wang C, McMahon SB, Pestell RG...MP, Wang C, Pestell RG. Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer. Oncotarget...MP, Quong A, Ertel A, Pestell RG. Cell fate factor DACH1 represses YB-1-mediated oncogenic transcription and translation. Cancer Res. 2014;74(3):829

ADP Regulates the Structure and Function of the Protein KaiC

Science.gov (United States)

2016-08-11

LiWang lab exploited this in vitro clock system to gain an atomic -resolution understanding of a circadian clock. The rationale is that fundamental...researchers are Hispanic. On a peer-reviewed research article from the LiWang lab, a Hispanic undergraduate student was an author, as were two non...Using both NMR and fluorescence spectroscopy , the LiWang lab showed that KaiA enhances KaiB-KaiC binding, and KaiC enhances KaiA-KaiB binding (Tseng et

Populações estelares do bojo galáctico

Science.gov (United States)

Escudero, A. V.; Costa, R. D. D.; Maciel, W. J.

2003-08-01

Os estudos mais recentes do bojo galáctico têm enfocado essencialmente as abundâncias químicas de elementos pesados, como o ferro, obtidos a partir das estrelas nas regiões centrais da galáxia. Elementos leves, como hélio, nitrogênio, oxigênio e argônio ainda são pouco estudados nestas regiões, devido à difícil determinação de suas abundâncias a partir de estrelas. Nestas condições as nebulosas planetárias desempenham um importante papel, pois permitem a determinação de abundâncias destes elementos usando técnicas de espectroscopia nebular. Neste trabalho, reportamos a análise das abundâncias químicas de uma nova amostra de nebulosas planetárias do bojo, bem como os resultados preliminares de um código numérico destinado a modelar a evolução química desta região. Usamos como vínculos observacionais os resultados obtidos das nebulosas planetárias, bem como de abundâncias estelares da região do bojo, obtidas da literatura. A partir deste modelo da evolução química e dos vínculos observacionais foi possível fazer um diagnóstico mais preciso das populações que constituem o bojo galáctico. O estudo destas populações que compõem a região central de nossa galáxia é de extrema importância para o maior entendimento da evolução química e dinâmica da galáxia como um todo. Por isto, verificamos a importância dos modelos de formação simples e mista utilizados para explicar características da população da região central da galáxia. Algumas destas características são: uma grande dispersão nos valores das abundâncias químicas e um grande espalhamento nas correlações entre as abundâcias de nitrogênio e oxigênio. Estas peculiaridades são dificilmente reproduzidas por modelos de formação simples, e portanto são importantes indícios da validade dos modelos de formação mista, tais como um rápido colapso do bojo seguido de uma evolução secular. (FAPESP, CNPq)

Retraction RETRACTION of "Methylation of the RASSFIA promoter in breast cancer" by Y. Ji, H.H. Jin, M.D. Wang, W.X. Cao, J.L. Bao - Genet. Mol. Res. 15 (2): gmr.15028261 (2016) - DOI: 10.4238/gmr.15028261.

Science.gov (United States)

Ji, Y; Jin, H H; Wang, M D; Cao, W X; Bao, J L

2016-10-07

The retracted article is: Ji Y, Jin HH, Wang MD, Cao WX, et al. (2016). Methylation of the RASSFIA promoter in breast cancer. Genet. Mol. Res. 15: gmr.15028261. There are significant parts of this article (particularly, in the discussion section) that are copied from "Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome", by Jia Xu, Priya B Shetty, Weiwei Feng, Carol Chenault, Robert C Bast Jr, Jean-Pierre J Issa, Susan G Hilsenbeck and Yinhua Yu, published in BMC Cancer 2012; 12: 243. DOI: 10.1186/1471-2407-12-243. The first paragraphs of both discussions are identical. This is concerning. The abstract and introduction sections have much of their text plagiarized. Overall, there is high plagiarism detected. The GMR editorial staff was alerted and after a thorough investigation, we have strong reason to believe that the peer review process was failure and, after review and contacting the authors, the editors of Genetics and Molecular Research decided to retract the article in accordance with the recommendations of the Committee on Publication Ethics (COPE). The authors and their institutions were advised of this serious breach of ethics.

Systematic review and meta-analysis: bezafibrate in patients with primary biliary cirrhosis

Directory of Open Access Journals (Sweden)

Yin Q

2015-09-01

Full Text Available Qin Yin,1,2,* Jingjing Li,3,* Yujing Xia,3 Rong Zhang,3,4 Jianrong Wang,3,4 Wenxia Lu,3,4 Yuqing Zhou,1,2 Yuanyuan Zheng,3 Huerxidan Abudumijiti,3 Rongxia Chen,3 Kan Chen,3 Sainan Li,3 Tong Liu,3 Fan Wang,3 Jie Lu,3 Yingqun Zhou,3 Chuanyong Guo3 1Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 2The First Affiliated Hospital of Soochow University, Suzhou, 3Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 4The First Clinical Medical College of Nanjing Medical University, Nanjing, People’s Republic of China *These authors contributed equally to this work and should be considered co-first authors Background and aim: Ursodeoxycholic acid (UDCA is the standard treatment for primary biliary cirrhosis (PBC, but not all cases respond well. Evidence has shown that combination therapy of UDCA with bezafibrate significantly improved liver function. A meta-analysis was performed to assess the efficacy and safety of UDCA and bezafibrate combination therapy in the treatment of PBC.Results: Nine trials, with a total of 269 patients, were included in the analysis. The bias risk of these trials was high. Compared with UDCA alone, the combination with bezafibrate improved the Mayo risk score (mean difference [MD], 0.60; 95% confidence interval [CI], 0.25–0.95; P=0.0008 and liver biochemistry: alkaline phosphatase (MD, -238.21 IU/L; 95% CI, -280.83 to -195.60; P<0.00001; gamma-glutamyltransferase (MD, -38.23 IU/L; 95% CI, -50.16 to -25.85; P<0.00001; immunoglobulin M (MD, -128.63 IU/L; 95% CI, -151.55 to -105.71; P<0.00001; bilirubin (MD, -0.20 mg/dL; 95% CI, -0.33 to -0.07; P=0.002; triglycerides (MD, -26.84 mg/dL; 95% CI, -36.51 to -17.17; P<0.0001; total cholesterol (MD, -21.58 mg/dL; 95% CI, -30.81 to -12.34; P<0.0001, and serum alanine aminotransferase (MD, -10.24 IU/L; 95% CI, -12.65 to -78.5; P<0.00001. However

China and the New International Order

DEFF Research Database (Denmark)

Jiang, Yang

2009-01-01

This article reviews the book "China and the New International Order," edited by Wang Gungwu and Zheng Yongnian.......This article reviews the book "China and the New International Order," edited by Wang Gungwu and Zheng Yongnian....

The Role of Retinal Determination Gene Network (RDGN) in Hormone Signaling Transduction and Prostate Tumorigenesis

Science.gov (United States)

2013-10-01

Wu K, Wang L, Jiao X, Ju X, Li Z, Ertel A, Addya S, McCue P, Lisanti MP, Wang C, Davis RJ, Mardon G, Pestell RG. Androgen therapy resistant...Li Z, Hu J, Chen K, Wu J, Pestell RG. DACH1 inhibited prostate cancer cellular proliferation and Interleukon-6 signaling. AACR 103rd Annual Meeting...March 31 – April 4, 2012, Chicago, IL.  Wang J, Cai S, Chen K, Sun Y, Li S, Pestell RG, Wu K. Regulation of AR transcriptional activity and

Protective effect of rhamnopyranosyl vanilloyl isolated from ...

African Journals Online (AJOL)

Cai Tian Di Wang in 2013 and authenticated by. Chang-Wu Wang, a ... purchased from Abcam (Cambridge, UK) and ..... Hosaka T, Suzuki F, Kobayashi M, Seko Y, Kawamura Y, ... Han JJ, Ning N. Research progress on pharmacological.

The fauna of the family Bombycidae sensu lato (Insecta, Lepidoptera, Bombycoidea) from Mainland China, Taiwan and Hainan Islands.

Science.gov (United States)

Wang, Xing; Wang, Min; Zolotuhin, Vadim V; Hirowatari, Toshiya; Wu, Shipher; Huang, Guo-Hua

2015-07-22

Seventy-seven species of family Bombycidae s. lat., belonging to 25 genera in three subfamilies, that have been recorded from China are listed and described, with illustrations of the adults, preimaginal stages (if available), and their genitalia. Keys to subfamilies and genera are provided. Two new genera and four new species are described, two subgenera are raised to generic status, seven new combinations are made, and one genus and six species are newly recorded from China. The new taxa are as follows: Rotunda Wang, X. & Zolotuhin, gen. nov., Comparmustilia Wang, X. & Zolotuhin, gen. nov., Triuncina daii Wang, X. & Zolotuhin, sp. nov., Triuncina xiongi Wang, X. & Zolotuhin, sp. nov., Gnathocinara boi Wang, X. & Zolotuhin, sp. nov. and Promustilia yajiangensis Wang, X. & Zolotuhin, sp. nov. The taxa newly recorded for China are: Sesquiluna Forbes, 1955; Trilocha friedeli Dierl, 1978; Bivincula kalikotei Dierl, 1978; Sesquiluna forbesi Zolotuhin & Witt, 2009; Mustilizans lepusa Zolotuhin, 2007; Smerkata brechlini (Zolotuhin, 2007) and Mustilia castanea Moore, 1879. The seven new combinations are: Rotunda rotundapex (Miyata & Kishida, 1990), comb. nov., Triuncina nitida (Chu & Wang, L.Y., 1993), comb. nov., Gunda sesostris (Vuillot, 1893), comb. nov., Smerkata fusca (Kishida, 1993), comb. nov., Comparmustilia sphingiformis (Moore, 1879), comb. nov., Comparmustilia semiravida (Yang, 1995), comb. nov., Comparmustilia gerontica (West, 1932), comb. nov.. The two subgenera raised to generic level are: Promustilia Zolotuhin, 2007, stat. nov. and Smerkata Zolotuhin, 2007, stat. nov.. The distributions of the species in China were determined and distributional maps provided. All type specimens of the new species described here are deposited in the College of Plant Protection, Hunan Agricultural University, China (HUNAU); Department of Entomology, South China Agricultural University, China (SCAU); Kyushu University Museum, Kyushu University, Japan (KUM), and Entomological

Liu et al., Afr J Tradit Complement Altern Med. (2016) 13(1):157-168 ...

African Journals Online (AJOL)

acer

Figure 4: The forest plot of LH levels. E2. 10 out of 12 RCTs (Xia et al., 2008; Deng et al., 2005; Cao et al., 2007; Xing et al., 2001; Yuan, 2006; Yan, 2002; Shi et al., 2008; Zhang et al., 2008; Yang, 2012) conducted a comparison of the therapeutic effects of E2 levels between integrated Chinese and western medicine and.

X-ray attenuation coefficients and photoelectric cross sections of Cu, Fe and Sn for the energy range 3-29 KeV

International Nuclear Information System (INIS)

Wang Dachun; Yang Hua; Luo Pingan; Ding Xunliang; Wang Xinfu; Zhou Hongyu; Shen Xinyin; Zhu Guanghua

1991-08-01

The document contains the following two papers: X-ray attenuation coefficient and photoelectric cross sections of Sn for the Energy Range 3.3 KeV to 29.1 KeV - by Wang Dachun, Yang Hua and Luo Pingan. X-ray attenuation coefficients and photoelectric cross sections of Cu and Fe for the range 3 KeV to 29 KeV - by Wang Dachun, Ding Xunliang, Wang Xinfu, Yang Hua, Zhou Hongyu, Shen Xinyin and Zhu Guanghua. A separate abstract was prepared for each of these papers. Refs, figs and tabs

mandarin (Citrus reticulata Blanco)

African Journals Online (AJOL)

ARL4

between 'Shatangju' and 'Wuzishatangju' based on establishing an optimization of ..... plant species (Han et al., 2008; Zhang et al., 2010). In this study, 153 pairs of SRAP .... Wang XP, Wang YJ, Zhang JX, Xu Y, Yang KQ (2003). Randomly.

Luteoloside Inhibits Proliferation of Human Chronic Myeloid ...

African Journals Online (AJOL)

Purpose: To investigate the effects of luteoloside on the proliferation of human chronic ..... Zhang N, Wang D, Zhu Y, Wang J, Lin H. Inhibition ... Han X. Protection of Luteolin-7-O-Glucoside Against ... Hwang YJ, Lee EJ, Kim HR, Hwang KA.

Extraction-condition Optimization of Baicalein and Schisandrin from ...

African Journals Online (AJOL)

effects of individual factors on extraction rates of baicalein and schisandrin determined by high performance liquid ..... Huang HL, Wang YJ, Zhang QY, Liu B, Wang FY, Li JJ,. Zhu RZ. ... Liu C, Zhao X, Fan Y, Han G, Nguyen T. Astragalus.

African Journal of Biotechnology - Vol 10, No 37 (2011)

African Journals Online (AJOL)

7130 ... G Lu, Y Shen, W Qian, L Shen, Q Qiao, M Li, Z Wang, 7136-7142 ... LN Zhen, K Wang, YJ Zhang, H Zhou, 7161-7165 ... Effect of cadmium hyperaccumulation on antioxidative defense and proline accumulation of Solanum nigrumL.

Growth, ion content and photosynthetic responses of two Elytrigia ...

African Journals Online (AJOL)

Jane

2011-07-25

Jul 25, 2011 ... Wang Zan, Zhang Geng, Wang Xue-min and Gao Hong-wen*. Institute of .... Dried leaf samples were ground to a fine powder and approximately. 0.1 g was .... structure and negative feedback by reduced sink activity. (Iyengar ...

Modeling Synergies in Large Human-Machine Networked Systems

Science.gov (United States)

2013-09-25

Agents and Multi- Agent Systems (AAMAS), Valencia, Spain, June 4-8, 2012. Steven Okamoto_, Praveen Paruchuri, Yonghong Wang, Katia Sycara, Janusz...Society, Santa Monica, CA: Human Factors and Ergonomics Society. 86. Steven Okamoto_, Praveen Paruchuri, Yonghong Wang, Katia Sycara, Janusz

The 2nd International Conference on Agricultural and Biological Sciences (ABS 2016

Directory of Open Access Journals (Sweden)

Lei Pei

2016-10-01

Full Text Available Table of contents 01 The influence of soil salt content on the photosynthetic characteristics of spring wheat with trickle irrigation Lei Pei, Zhenhua Wang, Jinzhu Zhang, Wenhao Li 02 Comparing growth of fast-growing and slow-growing endophytes in plants via ergosterol quantification Adeline SY Ting, Yiing Y Chow, Sadequr Rahman 03 Transcriptome and digital gene expression analysis identifies putative triterpene saponin-biosynthetic genes of Panax notoginseng Rongchang Wei 04 Chitosan-assisted isolation and antioxidant evaluation of flavonoids from Sophora japonica L. Zhang Hu, Sidong Li, Chuyan Li, Zijuan Li 05 Two kinds of new characteristics of the ektexine ornamentation of ginkgo pollen Guoxia Wang, Yuzhen Yang, Gang Chen, Qing Luo 06 Analysis of nutrient and medicinal ingredients of Ginkgo pollen in different regions Guoxia Wang, Ruixia Liu, Yuzhen Yang, Lipei Chen 07 Photosynthetic performance of greening seedlings of seven species to drought stress Zhiyang Lie, Tongtong Zhou, Weilong Huang, Li Xue 08 Changes of fluorescence parameters of greening seedlings of seven species under drought stress Jie Li, Zhuomin Wang, Li Xue 09 Mammalian sex hormone affects regeneration capacity and enzymes activity of Triticale L in vitro culture Ismail Bezirganoglu, Pınar Uysal 10 Fractional Fourier entropy increases the recognition rate of fruit type detection Shuihua Wang, Zhihai Lu, Jiquan Yang, Yudong Zhang, John Liu, Ling Wei, Shufang Chen, Preetha Phillips, Zhengchao Dong 11 Banana-peanut intercropping reduces Fusarium wilt disease in banana from enhancing soil bacterial microorganisms and leaf nutrition Hong Li, Xutong Wang, Fengliang Zhao, Guisheng Yang 12 Manganese stress impairs stem ureide nitrogen fixation in yardlong-bean plants in the acidic environment Hong Li 13 A new pest control method for Rhytidodera bowringii Larvae Haijie Huang, Li Zhao, Weijian Huang, Jinhui Wang, Zhongrun Zhang 14 Research on the seed-like Fruits of Subg. Sclarea of

Tropical Journal of Pharmaceutical Research - Vol 14, No 9 (2015)

African Journals Online (AJOL)

... on Zeste Homolog 2 (Ezh2) Enhancement in Human Esophageal Cell Lines ... Impact of Caryolanemagnolol on Gait and Functional Mobility on Individuals ... L Song, H Kang, D Liu, Z Dai, J He, B Wang, Y Zhao, X Wang, W Xi, 1719-1722 ...

Mechanisms of all-trans retinoic acid-induced differentiation of acute ...

Indian Academy of Sciences (India)

Author Affiliations. Ji-Wang Zhang1 Jian Gu1 Zhen-Yi Wang1 Sai-Juan Chen1 Zhu Chen1. Shanghai Institute of Hematology, Ruijin Hospital Affiliated to Shanghai Second Medical University, 197 Ruijin Road II, Shanghai 200025, People's Republic of China ...

Improving the limits of detection of low background alpha emission measurements

Science.gov (United States)

McNally, Brendan D.; Coleman, Stuart; Harris, Jack T.; Warburton, William K.

2018-01-01

Alpha particle emission - even at extremely low levels - is a significant issue in the search for rare events (e.g., double beta decay, dark matter detection). Traditional measurement techniques require long counting times to measure low sample rates in the presence of much larger instrumental backgrounds. To address this, a commercially available instrument developed by XIA uses pulse shape analysis to discriminate alpha emissions produced by the sample from those produced by other surfaces of the instrument itself. Experience with this system has uncovered two residual sources of background: cosmogenics and radon emanation from internal components. An R&D program is underway to enhance the system and extend the pulse shape analysis technique further, so that these residual sources can be identified and rejected as well. In this paper, we review the theory of operation and pulse shape analysis techniques used in XIA's alpha counter, and briefly explore data suggesting the origin of the residual background terms. We will then present our approach to enhance the system's ability to identify and reject these terms. Finally, we will describe a prototype system that incorporates our concepts and demonstrates their feasibility.

A new species of Neoperla (Plecoptera: Perlidae) from Zhejiang Province of China.

Science.gov (United States)

Chen, Zhi-Teng

2016-03-24

The stonefly genus Neoperla Needham (1905) is primarily distributed in eastern North America, Tropical and Temperate Asia and central Africa, with at least 297 species known (Illies 1966, Zwick 1973, Stark & Gaufin 1976, DeWalt et al. 2016). Contributions to Chinese species of Neoperla were made by Chu (1929), Wu & Claassen (1934), Wu (1935, 1938, 1948, 1962, 1973), Yang & Yang (1992, 1995, 1998), Du (1999, 2000a, 2000b), Du et al. (1999, 2001), Du & Sivec (2004, 2005), Du & Wang (2005, 2007), Sivec & Zwick (1987), Li & Wang (2011), Li et al. (2011a, 2011b, 2012a, 2012b, 2013a, 2013b, 2014a, 2014b), Qin et al. (2013), Wang et al. (2013a, 2013b), Li & Zhang (2014), Kong et al. (2014), Wang et al. (2014), Chen & Du (2015). Herein, a new species of this genus is described from Taizhou, Zhejiang Province, of eastern coastal China.

Renoprotective effect of remote ischemic postconditioning in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention

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Cao B

2018-02-01

Full Text Available Bangming Cao,* Chi Zhang,* Haipeng Wang, Ming Xia, Xiangjun Yang Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of China *These authors contributed equally to this work Background: Whether upper arm remote ischemic postconditioning (RIPostC exerts protection to kidney in patients with ST-elevation myocardial infarction (STEMI undergoing primary percutaneous coronary intervention (PPCI remains unknown. Methods: Sixty-four patients with STEMI were randomized to PPCI + RIPostC (n=29 and PPCI (n=35 groups. RIPostC consisting of 4 cycles of 5 minutes occlusion/reperfusion by cuff inflation/deflation of the upper arm was started within 1 minute after the first balloon dilatation. Peripheral venous blood samples were collected before PPCI and at 0.5, 8, 24, 48, and 72 hours after PPCI to detect serum creatinine (SCr and creatine kinase-MB (CK-MB. Acute kidney injury (AKI rate and estimated glomerular filtration rate (eGFR were calculated. The transthoracic echocardiography was performed 7 days after PPCI to assess left ventricular ejection fraction (LVEF. Results: The patients in the PPCI + RIPostC group had a lower AKI rate compared with those in the PPCI group (P=0.04. The eGFR after PPCI increased in the PPCI + RIPostC group compared to the PPCI group (P<0.01. The peak of CK-MB concentration in the PPCI + RIPostC group was significantly lower than that in the PPCI group (P<0.01. The area under the curve of CK-MB decreased in the PPCI + RIPostC group compared with that in the PPCI group. LVEF in the PPCI + RIPostC group was significantly higher than that in the PPCI group (P=0.04. Conclusion: Upper arm RIPostC exerts renal and cardiac protection following cardiac ischemia–reperfusion in patients with STEMI. Keywords: myocardial ischemia reperfusion, ST-segmental elevation myocardial infarction, primary percutaneous coronary intervention, remote ischemic postconditioning

CAG repeat polymorphisms in the androgen receptor and breast cancer risk in women: a meta-analysis of 17 studies

Directory of Open Access Journals (Sweden)

Mao Q

2015-08-01

Full Text Available Qixing Mao,1–3,* Mantang Qiu,1–3,* Gaochao Dong,3 Wenjie Xia,1–3 Shuai Zhang,1,3 Youtao Xu,1,3 Jie Wang,3 Yin Rong,1,3 Lin Xu,1,3 Feng Jiang1,3 1Department of Thoracic Surgery, Nanjing Medical University Affiliated Cancer Institute of Jiangsu Province, 2Fourth Clinical College of Nanjing Medical University, 3Jiangsu Key Laboratory of Molecular and Translational Cancer Research, Nanjing, People’s Republic of China *These authors contributed equally to this work Abstract: The association between polymorphic CAG repeats in the androgen receptor gene in women and breast cancer susceptibility has been studied extensively. However, the conclusions regarding this relationship remain conflicting. The purpose of this meta-analysis was to identify whether androgen receptor CAG repeat lengths were related to breast cancer susceptibility. The MEDLINE, PubMed, and EMBASE databases were searched through to December 2014 to identify eligible studies. Data and study quality were rigorously assessed by two investigators according to the Newcastle-Ottawa Quality Assessment Scale. The publication bias was assessed by the Begg’s test. Seventeen eligible studies were included in this meta-analysis. The overall analysis suggested no association between CAG polymorphisms and breast cancer risk (odds ratio [OR] 1.031, 95% confidence interval [CI] 0.855–1.245. However, in the subgroup analysis, we observed that long CAG repeats significantly increased the risk of breast cancer in the Caucasian population (OR 1.447, 95% CI 1.089–1.992. Additionally, the risk was significantly increased in Caucasian women carrying two alleles with CAG repeats ≥22 units compared with those with two shorter alleles (OR 1.315, 95% CI 1.014–1.707. These findings suggest that long CAG repeats increase the risk of breast cancer in Caucasian women. However, larger scale case-control studies are needed to validate our results. Keywords: androgen, CAG repeat polymorphism, women

Attacks, applications, and evaluation of known watermarking algorithms with Checkmark

Science.gov (United States)

Meerwald, Peter; Pereira, Shelby

2002-04-01

The Checkmark benchmarking tool was introduced to provide a framework for application-oriented evaluation of watermarking schemes. In this article we introduce new attacks and applications into the existing Checkmark framework. In addition to describing new attacks and applications, we also compare the performance of some well-known watermarking algorithms (proposed by Bruyndonckx,Cox, Fridrich, Dugad, Kim, Wang, Xia, Xie, Zhu and Pereira) with respect to the Checkmark benchmark. In particular, we consider the non-geometric application which contains tests that do not change the geometry of image. This attack constraint is artificial, but yet important for research purposes since a number of algorithms may be interesting, but would score poorly with respect to specific applications simply because geometric compensation has not been incorporated. We note, however, that with the help of image registration, even research algorithms that do not have counter-measures against geometric distortion -- such as a template or reference watermark -- can be evaluated. In the first version of the Checkmark benchmarking program, application-oriented evaluation was introduced, along with many new attacks not already considered in the literature. A second goal of this paper is to introduce new attacks and new applications into the Checkmark framework. In particular, we introduce the following new applications: video frame watermarking, medical imaging and watermarking of logos. Video frame watermarking includes low compression attacks and distortions which warp the edges of the video as well as general projective transformations which may result from someone filming the screen at a cinema. With respect to medical imaging, only small distortions are considered and furthermore it is essential that no distortions are present at embedding. Finally for logos, we consider images of small sizes and particularly compression, scaling, aspect ratio and other small distortions. The challenge

Novel functionalized nanoparticles for tumor-targeting co-delivery of doxorubicin and siRNA to enhance cancer therapy

Directory of Open Access Journals (Sweden)

Xia Y

2017-12-01

Full Text Available Yu Xia, Tiantian Xu, Changbing Wang, Yinghua Li, Zhengfang Lin, Mingqi Zhao, Bing Zhu Central Laboratory, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, People’s Republic of China Abstract: Human homeobox protein (Nanog is highly expressed in most cancer cells and has gradually emerged as an excellent target in cancer therapy, owing to its regulation of cancer cell proliferation, metastasis and apoptosis. In this study, we prepared tumor-targeting functionalized selenium nanoparticles (RGDfC-SeNPs to load chemotherapeutic doxorubicin (DOX and Nanog siRNA. Herein, RGDfC peptide was used as a tumor-targeting moiety which could specifically bind to αvβ3 integrins overexpressed on various cancer cells. The sizes of RGDfC-SeNPs@DOX nanoparticles (~12 nm were confirmed by both dynamic light scattering and transmission electron microscopy. The chemical structure of RGDfC-SeNPs@DOX was characterized via Fourier-transform infrared spectroscopy. The RGDfC-SeNPs@DOX was compacted with siRNA (anti-Nanog by electrostatic interaction to fabricate the RGDfC-SeNPs@DOX/siRNA complex. The RGDfC-SeNPs@DOX/siRNA complex nanoparticles could efficiently enter into HepG2 cells via clathrin-associated endocytosis, and showed high gene transfection efficiency that resulted in enhanced gene silencing. The in vivo biodistribution experiment indicated that RGDfC-SeNPs@DOX/siRNA nanoparticles were capable of specifically accumulating in the tumor site. Furthermore, treatment with RGDfC-SeNPs@DOX/siRNA resulted in a more significant anticancer activity than the free DOX, RGDfC-SeNPs@DOX or RGDfC-SeNPs/siRNA in vitro and in vivo. In summary, this study shows a novel type of DOX and siRNA co-delivery system, thereby providing an alternative route for cancer treatment. Keywords: nanoparticles, tumor targeting, drug delivery, doxorubicin, Nanog siRNA

Investigation of silk fibroin nanoparticle-decorated poly(L-lactic acid composite scaffolds for osteoblast growth and differentiation

Directory of Open Access Journals (Sweden)

Chen BQ

2017-03-01

Full Text Available Biao-Qi Chen,1 Ranjith Kumar Kankala,1,2 Ai-Zheng Chen,1,2 Ding-Zhu Yang,1 Xiao-Xia Cheng,1 Ni-Na Jiang,1,2 Kai Zhu,3,4 Shi-Bin Wang1,2 1Institute of Biomaterials and Tissue Engineering, 2Fujian Provincial Key Laboratory of Biochemical Technology, Huaqiao University, Xiamen, Fujian, 3Department of Cardiac Surgery, Zhongshan Hospital, Fudan University, 4Shanghai Institute of Cardiovascular Disease, Shanghai, People’s Republic of China Abstract: Attempts to reflect the physiology of organs is quite an intricacy during the tissue engineering process. An ideal scaffold and its surface topography can address and manipulate the cell behavior during the regeneration of targeted tissue, affecting the cell growth and differentiation significantly. Herein, silk fibroin (SF nanoparticles were incorporated into poly(L-lactic acid (PLLA to prepare composite scaffolds via phase-inversion technique using supercritical carbon dioxide (SC-CO2. The SF nanoparticle core increased the surface roughness and hydrophilicity of the PLLA scaffolds, leading to a high affinity for albumin attachment. The in vitro cytotoxicity test of SF/PLLA scaffolds in L929 mouse fibroblast cells indicated good biocompatibility. Then, the in vitro interplay between mouse preosteoblast cell (MC3T3-E1 and various topological structures and biochemical cues were evaluated. The cell adhesion, proliferation, osteogenic differentiation and their relationship with the structures as well as SF content were explored. The SF/PLLA weight ratio (2:8 significantly affected the MC3T3-E1 cells by improving the expression of key players in the regulation of bone formation, ie, alkaline phosphatase (ALP, osteocalcin (OC and collagen 1 (COL-1. These results suggest not only the importance of surface topography and biochemical cues but also the potential of applying SF/PLLA composite scaffolds as biomaterials in bone tissue engineering. Keywords: super critical fluids, surface topography, bone

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Three duplication events and variable molecular evolution characteristics involved in multiple GGPS genes of six Solanaceae species. FENG LI CHUNYANG WEI CHAN QIAO ZHENXI CHEN PENG WANG PAN WEI RAN WANG LIFENG JIN JUN YANG FUCHENG LIN ZHAOPENG LUO. RESEARCH NOTE Volume 95 Issue ...

General Lp-harmonic Blaschke bodies

Indian Academy of Sciences (India)

Home; Journals; Proceedings – Mathematical Sciences; Volume 124; Issue 1. General -Harmonic Blaschke Bodies. Yibin Feng Weidong Wang. Volume 124 Issue 1 February 2014 pp ... Author Affiliations. Yibin Feng1 Weidong Wang1. Department of Mathematics, China Three Gorges University, Yichang 443002, China ...

Effect of domains configuration on crystal structure in ferroelectric ...

Indian Academy of Sciences (India)

2017-09-09

Sep 9, 2017 ... It is well known that domains and crystal structure control the physical properties of ferroelectrics. ... The as-prepared ceramics were crushed to fine pow- ders. ..... [1] Gao J, Xue D, Wang Y, Wang D, Zhang L, Wu H et al 2011.

Glassy carbon electrodes modified with gelatin functionalized ...

Indian Academy of Sciences (India)

at room temperature, and unique thermal and mechanical ... amounts of 18 amino acids which is generally prepared by the .... also shows linear relativity to the pH with the slope of .... Wang X X, Wang J W and Yang N J 2007 Food Chem.

An efficient somatic embryogenesis based plant regeneration from ...

African Journals Online (AJOL)

ajl yemi

2010-03-05

Mar 5, 2010 ... Fang Yuan, Quan Wang, Qifang Pan, Guofeng Wang, Jingya Zhao, Yuesheng Tian and. Kexuan Tang*. Plant Biotechnology Research Center, School of Agriculture and Biology, Fudan-SJTU-Nottingham Plant Biotechnology. R&D Center, Shanghai Jiao Tong University, Shanghai 200240, P. R. China.

In Memory of Xia Ye%怀念夏野先生

Institute of Scientific and Technical Information of China (English)

陈应时

2005-01-01

夏野先生离开我们已经有十个年头了!回想起1995年12月26日那天早晨,夏楠在电话中哭着告诉我：“爸爸去世了。”我不敢相信这个噩耗会是真的,赶紧骑车到福园5号11室先生的住处,只见先生已经停止了呼吸,安祥地躺在床上。此时此刻的我,面对着先生已无话可说,惟有哭泣!

Recovery of DNA from agarose gel by trap method | Xia | African ...

African Journals Online (AJOL)

Recovery of DNA from agarose gel electrophoresis is a basic operation during molecular cloning. Circular or linear DNA fragments which vary from 1.5 to 6.5 kb and correspond to 1 kb marker can be recovered from 0.8 to 1.0% agarose gel smoothly with a simple and rapid trap method. The recovery efficiency could be ...

Polymeric Smart Skin Materials: Concepts, Materials, and Devices

Science.gov (United States)

2006-03-31

Fudouzi, H. and Xia, Y., Langmuir 2003, 19, 9653-9658 (also see the highlight in Materials Today, 2003, December, p. 7). 15. Langmuir - Blodgett Silver...development of electroactive dendrimers, dendronized polymers, hyperbranched polymers, and phase- separating block copolymers. Development of such materials...Dalton, and A. K-Y. Jen, " Hyperbranched Fluorinated Aromatic Polyester from Mild One-Pot Polymerization of AB 2 Hydroxy Acid Monomer," Macromolecules

Combining Ketamine and Virtual Reality Pain Control During Severe Burn Wound Care: One Military and One Civilian Patient

Science.gov (United States)

2011-01-01

effects include nausea/ vomiting, constipation , sedation, interference with sleep cycles, increased irritability, itching, urinary retention, cog...Xia J, Hailan W. Ketamine and lornoxicam for preventing a fentanyl-induced increase in postoperative morphine requirement. Anesth Analg 2008;107(6...verbal pain descriptors. Pain 1978;5:5–18. 30 Hoffman HG, Patterson DR, Magula J, et al. Water - friendly virtual reality pain control during wound

Systems biology of coagulation initiation: kinetics of thrombin generation in resting and activated human blood.

Directory of Open Access Journals (Sweden)

Manash S Chatterjee

2010-09-01

Full Text Available Blood function defines bleeding and clotting risks and dictates approaches for clinical intervention. Independent of adding exogenous tissue factor (TF, human blood treated in vitro with corn trypsin inhibitor (CTI, to block Factor XIIa will generate thrombin after an initiation time (T(i of 1 to 2 hours (depending on donor, while activation of platelets with the GPVI-activator convulxin reduces T(i to ∼20 minutes. Since current kinetic models fail to generate thrombin in the absence of added TF, we implemented a Platelet-Plasma ODE model accounting for: the Hockin-Mann protease reaction network, thrombin-dependent display of platelet phosphatidylserine, VIIa function on activated platelets, XIIa and XIa generation and function, competitive thrombin substrates (fluorogenic detector and fibrinogen, and thrombin consumption during fibrin polymerization. The kinetic model consisting of 76 ordinary differential equations (76 species, 57 reactions, 105 kinetic parameters predicted the clotting of resting and convulxin-activated human blood as well as predicted T(i of human blood under 50 different initial conditions that titrated increasing levels of TF, Xa, Va, XIa, IXa, and VIIa. Experiments with combined anti-XI and anti-XII antibodies prevented thrombin production, demonstrating that a leak of XIIa past saturating amounts of CTI (and not "blood-borne TF" alone was responsible for in vitro initiation without added TF. Clotting was not blocked by antibodies used individually against TF, VII/VIIa, P-selectin, GPIb, protein disulfide isomerase, cathepsin G, nor blocked by the ribosome inhibitor puromycin, the Clk1 kinase inhibitor Tg003, or inhibited VIIa (VIIai. This is the first model to predict the observed behavior of CTI-treated human blood, either resting or stimulated with platelet activators. CTI-treated human blood will clot in vitro due to the combined activity of XIIa and XIa, a process enhanced by platelet activators and which proceeds

Análise cinemática bi-dimensional dos núcleos de NGC 4051 e NGC 4941

Science.gov (United States)

Barbosa, F. K. B.; Storchi-Bermagnn, T.; Schmitt, H. R.; Cid Fernandes, R.; Winge, C.

2003-08-01

Estudos recentes da cinemática da região dentro de 1 kpc do núcleo de galaxias Seyfert próximas usando espectroscopia de fenda longa com alta resolução espacial (~ 100 pc ou melhores) encontraram uma queda na dispersão de velocidades nas regiões centrais dentro de um raio de ~ 300 pc do núcleo. Essa queda vem sendo tentativamente explicada por um cenário evolutivo em que um evento de formação estelar recente cria as estrelas da região central em um disco de dimensões 300 pc. Desde sua criação, tais estrelas não tiveram tempo de "virializar", ou seja, seguir a distribuição radial de dispersões de velocidades determinada pelo campo gavitacional da galáxia e, portanto, a dispersão de velocidades medida nessa região do bojo acaba sendo menor do que a dispersão medida nas vizinhanças. No presente trabalho investigamos a cinemática estelar no núcleo das galáxias Seyfert NGC 4051 e NGC 4941 usando o tripleto do Ca ii (8500 Å) em absorção. Os dados foram obtidos com o IFU GMOS no telescópio Gemini. O elemento de resolução espacial nas galáxias é da ordem de 30 pc. No intervalo espectral coberto pelo espectrografo a linha [S iii] (9068 Å) também é visível, o que permite estudar a cinemática do gás na mesma região. Serão apresentados mapas bi-dimensionais da velocidade e dispersão de velocidades das estrelas e do gás, além de imagens na linha [S iii] que mapeia o gás de alta excitação.

Sensing of polymeric sensor-based rhodamine B derivative for metal ...

Indian Academy of Sciences (India)

TONG-MOU GENG1 XIE WANG1 FENG ZHU1 HUI JIANG1 YU WANG2. Collaborative Innovation Center for Petrochemical New Materials, Anhui Key Laboratory of Functional Coordination Compounds, School of Chemistry and Chemical Engineering, Anqing Normal University, Anqing 246011, People's Republic of China ...

Functional Hybrid Nano-Oxides

Science.gov (United States)

2015-10-26

crucial in the education of several PhD students (Ilya Valmiansky, Mikhail Erekhinsky, Ali Basaran, Siming Wang, Sebastian Dietze, Elsa Abreu...Schuller, Phys. Rev. B 92, 085150(2015) 12. Dynamic Conductivity Scaling in Photoexcited V2O3 Thin Films, Elsa Abreu, Siming Wang, Juan Gabriel

African Journal of Biotechnology - Vol 10, No 7 (2011)

African Journals Online (AJOL)

Effects of deoxycycline induced lentivirus encoding FasL gene on apoptosis of Th1 cells · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. H Luo, T Wang, A Luo, J Wang, Y Zhao, H Jiang, Q Shi, 1081-1087 ...

X-ray structure, hydrogen bonding and lattice energy analysis of (2E ...

Indian Academy of Sciences (India)

tion data for both the compounds were collected on an X'Calibur CCD area detector diffractometer (Oxford Diffrac- tion) using MoKa .... (Oxford Diffraction make, U.K.) ..... [4] Wang L, Chen G, Lu X, Wang S, Han S, Li Y, Ping G, Jiang. X, Li H ...

Isolation and characterization of sixty sequences of cot-1 DNA from ...

African Journals Online (AJOL)

user

2012-11-06

Nov 6, 2012 ... this study were from U. t. ussuricus animals raised in the Beijing. Zoo. ..... Collins F, Guyer MS, Peterson J, Felsenfeld A, Wetterstrand KA,. Patrinos A ... B, Ni P, Lin R, Qian W, Wang G, Yu C, Nie W, Wang J, Wu Z, Liang.

Cardioprotective effect of Shenxiong glucose injection on acute ...

African Journals Online (AJOL)

Yu JH, Wang LY, Akinyi M, Li YH, Duan ZZ, Zhu Y, Fan. GW. Danshensu protects ... Yin Y, Guan Y, Duan JL, Wei G, Zhu YR, Quan W, Guo. C, Zhou D, Wang YH, ... HM, Han J, Kang D. Lamotrigine increases intracellular. Ca(2+) levels and ...

Bulletin of Materials Science | Indian Academy of Sciences

Indian Academy of Sciences (India)

Author Affiliations. Baoan Liu1 Shaotao Sun2 Bo Wang1 Xun Sun1 Zhengping Wang1 Xinguang Xu1. State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, PR China; Administration Center, Shandong Academy of Information and Communication Technology, Jinan 250101, PR China ...

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Chemical Sciences. Hongling Wang. Articles written in Journal of Chemical Sciences. Volume 120 Issue 4 July 2008 pp 419-424. Microdetermination of human serum albumin by differential pulse voltammetry at a L-cysteine modified silver electrode · Liyuan Lu Yanqin Zi Hongling Wang.

Editorial

Directory of Open Access Journals (Sweden)

Irene Machado

2008-11-01

Full Text Available As preocupações teóricas que, há dois anos, deflagraram o projeto editorial de Galáxia foram tematizados sob vários pontos de vista nesse número. Desde sua primeira edição, a revista vem defendendo a noção de transdisciplinaridade, seja como forma de abordagem dos diferentes fenômenos da cultura, seja como tema mesmo de várias das intervenções teóricas nela abrigadas. Privilegiar o trânsito entre disciplinas e abordagens, porém, não é um exercí­cio acadêmico. Traduz a compreensão que orienta a abordagem semiótica no tratamento dos produtos da cultura planetária, de suas formas comunicacionais e artí­sticas totalmente mergulhadas nas chamadas novas tecnologias (sistemas digitais, ambientes de rede, realidade virtual, bem como de suas comunidades multiculturais. O exercí­cio transdisciplinar pareceu-nos uma estratégia fundamental para o tratamento de problemas postos na cultura graças ao arrefecimento entre dicotomias ou campos tidos como oponentes. A discussão sobre as relações entre mí­dia e arte inserem-se, com ênfase, nesse novo contexto. Esse é um dos temas inquietantes que está na mente dos pesquisadores e, por isso mesmo, organizou a pauta de discussão deste quarto número de Galáxia. Alguns enfrentamentos sobre o encontro entre arte e mí­dia foram apresentados nos ensaios que compõem o fórum. A intervenção de Arlindo Machado convida o leitor a desfazer equí­vocos: não existe arte que possa prescindir dos meios de seu tempo. Evidentemente sua fala traduz uma linha vigorosa de seu pensamento: a impossibilidade de se pensar comunicação fora do diálogo com as artes e suas linguagens. Ana Claudia de Oliveira enfrentou a tarefa de análise de produções artí­sticas realizadas com os meios e mí­dias de seu tempo para dar conta de um problema caro à comunicação: as estratégias de interação. Embora o foco de seu interesse seja a arte contemporânea, suas idéias confrontam

Synthesis and characterization of CuO nanoparticles using strong ...

Indian Academy of Sciences (India)

classified into three types on the basis of their dimension, i.e., one-, two- and ... dependent on the shape, size, composition and structures of the nanocrystals. ..... [43] Liu J, Jin J, Deng Z, Huang S-Z, Hu Z-Y, Wang L, Wang C,. Chen L-H, Li Y, ...

Effects of traditional Chinese medicine on rats with Type II diabetes ...

African Journals Online (AJOL)

Effects of traditional Chinese medicine on rats with Type II diabetes induced by high-fat diet and streptozotocin: A urine metabonomic study. H Zhao, Z Li, G Tian, K Gao, Li Zhiyong, B Zhao, J Wang, L Luo, Q Pan, W Zhang, Z Wu, J Chen, W Wang ...

Cold stratification, but not stratification in salinity, enhances seedling ...

African Journals Online (AJOL)

Cold stratification, but not stratification in salinity, enhances seedling growth of wheat under salt treatment. L Wang, HL Wang, CH Yin, CY Tian. Abstract. Cold stratification was reported to release seed dormancy and enhance plant tolerance to salt stress. Experiments were conducted to test the hypothesis that cold ...

Estimation of genetic and genotypic parameters for growth and ...

African Journals Online (AJOL)

Bekezela

2013-12-18

Dec 18, 2013 ... These included 50 Dongan chickens (DA) from Dongan county, 50 ..... Chang, G.B., Chang, H., Liu, X.P., Wang, H.Y., Xu, W., Zhao, W.M. & Wang, Q.H., 2005. ... Su, Y., Chen, G.H., Long, R.J., Bao, W.B. & Wan, J.H., 2006.

Bees and Honey

Institute of Scientific and Technical Information of China (English)

TOM; HANCOCK

2011-01-01

The first bee landed on Dalin Wang at around one in the afternoon.Surrounded by3,000 onlookers,he wore a pair of trousers,black boots and two small cloth bags,each containing a queen bee.Wang watched the bees cover his chest,legs and arms,until every

Stability of organic matter in soils of the Belgium Loess Belt upon erosion and deposition

NARCIS (Netherlands)

Wang, X.; Cammeraat, E.; Wang, Z.; Govers, G.; Kalbitz, K.

2011-01-01

Stability of organic matter in soils of the Belgium Loess Belt upon erosion and deposition X. Wang, L.H. Cammeraat, Z. Wang, G. Govers, K. Kalbitz. Abstract: Soil erosion has significant impacts on terrestrial C dynamics, which removes C from topsoil and continually exposes subsoil that has lower C

Discussion of "Carbon benefits of wolfberry plantation on secondary saline land in Jingtai oasis, Gansu - A case study on application of the CBP model" by Yaolin Wang, Chuanyan Zhao, Quanlin Ma, Yingke Li, Hujia Jing, Tao Sun, Eleanor Milne, Mark Easter, Keith Paustian, Hoi Wen Au Yong, John McDonagh (2015) [Journal of Environmental Management 157, 303-310].

Science.gov (United States)

Azarnivand, Ali

2015-12-01

Wang et al. (2015) employed driving force-pressure-state-impact-response (DPSIR) framework to provide a robust decision-making structure for carbon emission reduction by use of wolfberry plantation in the Jingtai oasis, China. DPSIR appropriately identified the causes of problem along with adopting the responses to the barriers associated with wolfberry plantation. However, the discusser argues that, the paper could have prepared more viable outcomes, if the authors had used causal network rather than causal chains through the DPSIR framework. Furthermore, they could have quantified the mutual relationship among the relevant factors to provide a detailed economic assessment. With this knowledge in hand, the current discussion letter suggests eDPSIR and meDPSIR to address drawbacks regarding conventional DPSIR framework. Due to proper performance of eDPSIR and meDPSIR, they are recommended as practical tools in the future environmental studies. Copyright © 2015 Elsevier Ltd. All rights reserved.

Information systems and computing technology

CERN Document Server

Zhang, Lei

2013-01-01

Invited papersIncorporating the multi-cross-sectional temporal effect in Geographically Weighted Logit Regression K. Wu, B. Liu, B. Huang & Z. LeiOne shot learning human actions recognition using key posesW.H. Zou, S.G. Li, Z. Lei & N. DaiBand grouping pansharpening for WorldView-2 satellite images X. LiResearch on GIS based haze trajectory data analysis system Y. Wang, J. Chen, J. Shu & X. WangRegular papersA warning model of systemic financial risks W. Xu & Q. WangResearch on smart mobile phone user experience with grounded theory J.P. Wan & Y.H. ZhuThe software reliability analysis based on

Cryptanalysis of the public key encryption based on multiple chaotic systems

International Nuclear Information System (INIS)

Zhang Linhua

2008-01-01

Recently, Ranjan proposed a novel public key encryption technique based on multiple chaotic systems [Phys Lett 2005;95]. Unfortunately, Wang soon gave a successful attack on its special case based on Parseval's theorem [Wang K, Pei W, Zhou L, et al. Security of public key encryption technique based on multiple chaotic system. Phys Lett A, in press]. In this letter, we give an improved example which can avoid the attack and point out that Wang cannot find the essential drawback of the technique. However, further experimental result shows Ruanjan's encryption technique is inefficient, and detailed theoretic analysis shows that the complexity to break the cryptosystem is overestimated

Identical and Nonidentical Synchronization of Hyperchaotic Systems by Active Backstepping Method

Directory of Open Access Journals (Sweden)

A. Abooee

2012-09-01

Full Text Available This paper focuses on the tracking and synchronization problems of hyperchaotic systems based on active backstepping method. The method consists of a recursive approach that interlaces the choice of a Lyapunov function with the design of feedback control. First, a nonlinear recursive active backstepping control vector is designed to track any desired trajectory in hyperchaotic Wang system. Furthermore, this method is applied to achieve hyperchaos synchronization of two identical hyperchaotic Wang systems. Also, it is used to implement global asymptotic synchronization between hyperchaotic Wang system and hyperchaotic Rössler system. Numerical simulations have been employed to verify the effectiveness of the three designed active backstepping control vectors.

Journal of Chemical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

CHEN AI-HUA1 MENG SU-CI2 ZHOU KAI1 WANG CONG-CONG1 ZHAO WEI2 WANG AI-JIAN2 QIAN JUN2. School of Chemistry & Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, People's Republic of China; School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang ...

Phase-Resolved Spectra of PSR B0525+21 and PSR B2020+28 JL ...

Indian Academy of Sciences (India)

J. L. Chen1,2, H. G. Wang3,∗. & N. Wang1. 1Xinjiang Astronomical Observatory, 150, Science-1 Street, Urumqi, Xinjiang 830011, China. 2Graduate University of the Chinese Academy of Scienes, 19A Yuquan Road, Beijing. 100049, China. 3Center for Astrophysics, Guangzhou University, Guangzhou 510006, China. ∗.

Investigations of Tissue-Level Mechanisms of Primary Blast Injury Through Modeling, Simulation, Neuroimaging and Neuropathological Studies

Science.gov (United States)

2012-07-10

2007;25(1):97-98. [19] Stewart C. Blast Injuries. Colorado Springs: USAF Academy Hospital; 2006. 88 p. [20] Cernak I, Wang Z, Jiang J, Bian X, Savic J...Wang Z, Jiang J, Bian X, Savic J. Ultrastructural and Functional Characteristics of Blast Injury- Induced Neurotrauma. Journal of Trauma: Injury

Proteomic analysis of human oral verrucous carcinoma | Wang ...

African Journals Online (AJOL)

Peptide mass fingerprints (PMFs) obtained by the MALDI-TOF analysis were applied to National Center for Biotechnology Information (NCBI), SWISS-PROT and MSDB databases using Mascot software. Then the 2-DE gel imaging showed that 74, 36 and 31 differential protein spots were found between OVC and OSCC, ...

76 FR 72387 - Order Relating to Xun Wang

Science.gov (United States)

2011-11-23

... was under construction in Islamabad, Pakistan, and was a subordinate entity under the ownership and... and timely payment of $200,000 as set forth above. Second, that, pursuant to the Debt Collection Act... facilitates the acquisition or attempted acquisition by the Denied Person of the ownership, possession, or...

Resilient Control and Intrusion Detection for SCADA Systems

Science.gov (United States)

2014-05-01

Lowe. The myths and facts behind cyber security risks for industrial control systems . VDE Congress, 2004. [45] I. S. C37.1-1994. Ieee standard...Resilient Control and Intrusion Detection for SCADA Systems Bonnie Xia Zhu Electrical Engineering and Computer Sciences University of California at...3. DATES COVERED 00-00-2014 to 00-00-2014 4. TITLE AND SUBTITLE Resilient Control and Intrusion Detection for SCADA Systems 5a. CONTRACT

Further improvement of N6 medium for callus induction and plant ...

African Journals Online (AJOL)

user

2011-03-02

Mar 2, 2011 ... bryos before or after transformation (Wang et al., 2009). Comparing to rice and ... regeneration, which heavily depends on several model inbred lines, such as ..... Tang FD, Liang YJ, Han SJ, Gong WG, Ding BY (2004). Effect of ... Wang K, Frame B, Ishida Y, Komari T (2009) Maize Genetic. Transformation.

Frequency upconversion in catechin assisted : - square nanoplates

Indian Academy of Sciences (India)

VAIRAPPERUMAL TAMILMANI

2017-11-25

Nov 25, 2017 ... out to be a prominent ligand for its coordination on the surface of the ..... C 113. 14702. 12. Jin J, Gu Y J, Man C W Y, Cheng J, Xu Z, Zhang Y, Wang .... Ding B, Han C, Zheng L, Zhang J, Wang R and Tang. Z 2015 Tuning ...

The Religion of Learning English in "English": A Language Educator's Reading

Science.gov (United States)

Gao, Xuesong

2011-01-01

This essay is my reading of "English," a novel based on author Wang Gang's experiences in Urumqi, Xinjiang Uyghur Autonomous Region, Northwest China during the Cultural Revolution (1966-1976). As a language educator, I was particularly interested in the way that Wang describes learning English in the novel. The essay focuses on three…

African Journal of Biotechnology - Vol 9, No 51 (2010)

African Journals Online (AJOL)

Osmotic potential of Zinnia elegans plant material affects the yield and morphology of tracheary elements produced in vitro · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD ... TEXT DOWNLOAD FULL TEXT. C Song, X Cao, KK Nicholas, C Wang, X Li, X Wang, J Fang, 8726-8730 ...

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Items 51 - 100 of 1309 ... Li-Long Liu, Kai Xu, Lu-Mei Kang, Shu-Ping Jiang, Qing-Hua Wang, ... CR Sewani-Rusike, JE Iputo, EJ Ndebia, M Gondwe, DR Kamadyaapa ... K-M Man, W-C Chen, H-M Wang, H-Y Chen, J-L Shen, L-D Chen, F-J Tsai, ...

Genetic dissection of chlorophyll content at different growth stages in ...

Indian Academy of Sciences (India)

57 were registered by Henan in 2006 (Hai and Kang 2007) and by state (China) ... autumn of 2006, the lines were grown in a plot with four 2-m rows spaced 25 ..... 1255–1264. Wang F. H., Wang G. X., Li X. Y., Huang J. L. and Zheng J. K. 2008.

Association of HS6ST3 gene polymorphisms with obesity and ...

Indian Academy of Sciences (India)

Supplementary data: Association of HS6ST3 gene polymorphisms with obesity and triglycerides: gene × gender interaction. Ke-Sheng Wang, Liang Wang, Xuefeng Liu and Min Zeng. J. Genet. 92, 395–402. Table 1. Associations of 117 SNPs with obesity in the Health ABC and Marshfield samples. Minor. OR Health.

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Genetics. CHU-ZHAO LEI. Articles written in Journal of Genetics. Volume 89 Issue 2 August 2010 pp 233-236 Research Note. Two novel single nucleotide polymorphisms (SNPs) and 4-bp deletion mutation of RBP4 gene in Chinese cattle · Mou Wang Xinsheng Lai Hui Yu Juqiang Wang ...

A simple extension of “An alternative approach to sea surface aerodynamic roughness” by Zhiqiu Gao, Qing Wang, and Shouping Wang

Science.gov (United States)

Gao, Zhiqiu; Wang, Linlin; Bi, Xueyan; Song, Qingtao; Gao, Yuchao

2012-08-01

Based on the data previously collected during the Humidity Exchange over the Sea Main Experiment (HEXMAX), the methods used to parameterize aerodynamic roughness (z0), friction velocity (u*), and the neutral drag coefficient (CDN) under moderate wind speed conditions originally proposed by Gao et al. (2006) were extended by using the nondimensional significant wave height (gHs/u*2 or gHs/U10N2) instead of wave age (cp/u* or cp/U10N), where g is the acceleration of gravity, Hs is the significant wave height, U10Nis the horizontal wind speed at 10-m height under the neutral atmospheric condition, andcp is the phase velocity of the peak wave spectrum. The results show (1) u* = 0.024U10N(gHs/U10N2)-1/4, (2) z0 = 10 × exp[-4.797(gHs/u*2)1/6] or z0 = 10 × exp[-16.613(gHs/U10N2)1/4], and (3) CDN = 0.007(gHs/u*2)-1/3 or CDN = 5.76 × 10-4(gHs/U10N2)-1/2. The present parameterization schemes were experimentally tested.

The Ser311Cys variation in the paraoxonase 2 gene increases the ...

Indian Academy of Sciences (India)

Supplementary data: The Ser311Cys variation in the paraoxonase 2 gene increases the risk of type 2 diabetes in northern Chinese. Yanchun Qu, Ze Yang, Feng Jin, Liang Sun, Chuanfang Zhang, Linong Ji, Hong Sun, Binyou Wang and Li Wang. J. Genet. 87, 165–169. Table 1. Clinical characteristics of case and control.

Untitled

African Journals Online (AJOL)

antibodies to egg drop syndrome. 1976 (EDS-76) and infectious bursal disease viruses. Avian Pathology, 12: 35 - 39. YUAN, X., WANG, Y., LI, J., YU, K.,. YANG, J., XU, H., ZHANG, Y., AI,. H. and WANG, J. (2013). Surveillance and molecular characterization of Newcastle disease virus in seafowl from coastal areas of China ...

Isolation of Stilbenoids and Lignans from Dendrobium hongdie

African Journals Online (AJOL)

Chen YG, Xu JJ, Yu H, Qing C, Zhang YL, Wang LQ, Liu. Y, Wang JH. Cytotoxic phenolics from Bulbophyllum odoratissimum. Food Chem, 2008; 107: 169–173. 17. Hernández-Romero Y, Acevedo L, Sánchez MLÁ, Shier. WT, Abbas HK, Mata R. Phytotoxic activity of bibenzyl derivatives from the Orchid Epidendrum rigidum.

Bulletin of Materials Science | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Bulletin of Materials Science. HUA WANG. Articles written in Bulletin of Materials Science. Volume 36 Issue 3 June 2013 pp 389-393. Effects of Bi doping on dielectric and ferroelectric properties of PLBZT ferroelectric thin films synthesized by sol–gel processing · Hua Wang Li Liu Ji-Wen Xu Chang-Lai Yuan ...

A new record and two new species of Cryptochironomus Kieffer, 1918 from China (Diptera, Chironomidae).

Science.gov (United States)

Yan, Chuncai; Zhao, Guangjun; Liu, Ting; Guo, Qin; Hou, Ziyuan; Wang, Xinhua; Pan, Baoping

2016-12-19

Two new species of the genus Cryptochironomus Kieffer, C. maculus Yan & Wang sp. n. and C. protuberans Yan & Wang sp. n. are described and illustrated as adult males. C. albofasciatus (Staeger) is recorded from China for the first time. A key to the males of Cryptochironomus in China is presented and generic diagnosis is emended.

Fibrinolysis and anticoagulant potential of a metallo protease ...

Indian Academy of Sciences (India)

In this study, a potent fibrinolytic enzyme-producing bacterium was isolated .... Time courses of growth and enzyme production in a culture of B. subtilis K42: ..... on a large scale in industry,would make thisoperation rapid .... Process. Biochem. 41 1545–1552. Wang SL, Kao TY, Wang CL, Yen YH, Chern MK and Chen YH.

P chromosomes involved in intergenomic rearrangements of ...

Indian Academy of Sciences (India)

2014-04-08

Apr 8, 2014 ... [Wang Q., Han H., Gao A., Yang X. and Li L. 2014 P chromosomes ... Y, were affected predominantly by ecological factors and altitude in nine populations of Kengyilia thoroldiana (Wang et al. 2012). To investigate the effects of different altitudes on .... AB51 0LX, UK) for improving the article linguistically.

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African Journals Online (AJOL)

Items 201 - 250 of 2037 ... Vol 14, No 11 (2015), Antibacterial Activity and Mode of Action of Mentha arvensis Ethanol Extract against Multidrug-Resistant Acinetobacter baumannii, Abstract PDF. Ling Zhang, Shu-gen Xu, Wei Liang, Jun Mei, Yue-ying Di, Hui-hua Lan, Yan Yang, Wei-wei Wang, Yuan-yuan Luo, Hou-zhao Wang.

Functional Analysis of Frequent Lung Cancer Amplicons Under Current Genome Annotation

Science.gov (United States)

2015-12-01

Zhang, Z., Wang, T., Winter, D., Keefe , D., Birney, E., Iyer, V. R., Lieb, J. D., Crawford, G. E., Li, G., Sandhu, K. S., Zheng, M., Wang, P., Luo, O...Herrero, J., Johnson, N., Keefe , D., Lukk, M., Luscombe, N. M., Sobral, D., Vaquerizas, J. M., Wilder, S. P., Batzoglou, S., Sidow, A., Hussami, N

Impossibility results for the equational theory of timed CCS

NARCIS (Netherlands)

Aceto, L.; Ingólfsdóttir, A.; Mousavi, M.; Mossakowski, T.; Montanari, U.; Haveraaen, M.

2007-01-01

We study the equational theory of Timed CCS as proposed by Wang Yi in CONCUR’90. Common to Wang Yi’s paper, we particularly focus on a class of linearly-ordered time domains exemplified by the positive real or rational numbers. We show that, even when the set of basic actions is a singleton, there

A new manufacturing process to remove thrombogenic factors (II, VII, IX, X, and XI) from intravenous immunoglobulin gamma preparations.

Science.gov (United States)

Park, Dong Hwarn; Kang, Gil Bu; Kang, Dae Eun; Hong, Jeung Woon; Lee, Min Gyu; Kim, Ki Yong; Han, Jeung Whan

2017-01-01

Coagulation factors (II, VII, IX, X, and particularly XIa) remaining in high concentrations in intravenous immunoglobulin (IVIG) preparations can form thrombi, causing thromboembolic events, and in serious cases, result in death. Therefore, manufacturers of biological products must investigate the ability of their production processes to remove procoagulant activities. Previously, we were able to remove coagulation factors II, VII, IX, and X from our IVIG preparation through ethanol precipitation, but factor XIa, which plays an important role in thrombosis, remained in the intermediate products. Here, we used a chromatographic process using a new resin that binds with high capacity to IgG and removes procoagulant activities. The procoagulant activities were reduced to low levels as determined by the thrombin generation assay: 250 s, FXI/FXIa ELISA: <0.31 ng/mL. Even after spiking with FXIa at a concentration 32.5 times higher than the concentration in normal specimens, the procoagulant activities were below the detection limit (<0.31 ng/mL). These results demonstrate the ability of our manufacturing process to remove procoagulant activities to below the detection limit (except by NaPTT), suggesting a reduced risk of thromboembolic events that maybe potentially caused by our IVIG preparation. Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Prevalence and risk factors for COPD in greenhouse farmers: a large, cross-sectional survey of 5,880 farmers from northeast China

Directory of Open Access Journals (Sweden)

Liu S

2015-10-01

Full Text Available Shuo Liu,1 Yangang Ren,1 Deliang Wen,1 Yu Chen,2 Donghong Chen,1 Liyun Li,3 Xuhua Zhang,1 Yibing Zhang,4 Shuang Fu,5 Zhenhua Li,3 Shuyue Xia,6 Dongliang Wang,7 Hong Chen,8 Jian Zhao,9 Xiaoge Wang1 1The Fourth Affiliated Hospital, 2The Second Affiliated Hospital, 3The First Affiliated Hospital, China Medical University, 4The Shenyang Military General Hospital, Shenyang, 5The General Hospital of Fushun Mining Bureau, Fushun, 6Fengtian Hospital, Shenyang Medical College, 7202nd Hospital of People’s Liberation Army, Shenyang, 8The First People’s Hospital of Kazuo, Chaoyang, 9205th Hospital of People’s Liberation Army, Jinzhou, Liaoning, People’s Republic of China Background: COPD is one of the most common chronic diseases, and more and more farmers who were frequently exposed to greenhouse environments were diagnosed with COPD. However, little information is available on the prevalence of COPD among the greenhouse farmers. This study was conducted to assess the prevalence of COPD and investigate the potential risk factors for COPD among the Chinese greenhouse farmers.Methods: Cross-sectional studies involving a sample of greenhouse farmers living in northeast China were performed via stratified-cluster-random sampling. All subjects were interviewed using a uniform questionnaire and underwent pulmonary function tests between 2006 and 2009, based on the diagnostic criteria of the Global Initiative for Chronic Obstructive Lung Disease. Multiple logistic regression analysis was conducted to examine the risk factors for COPD.Results: Of the 5,880 greenhouse farmers from northeast China who were originally selected for this study, 5,420 questionnaires were completed. The overall prevalence of COPD in greenhouse farmers was 17.5%. The COPD prevalence was significantly higher in elderly subjects (≥50 years, current smokers, in those with lower body mass index (≤18.5 kg/m2 and less education, in those who were exposed to mushroom, flowers and

Multivoxel magnetic resonance spectroscopy identifies enriched foci of cancer stem-like cells in high-grade gliomas

Directory of Open Access Journals (Sweden)

He T

2017-01-01

Full Text Available Tao He,1–3,* Tianming Qiu,4,* Xiaodong Wang,5 Hongxing Gui,6 Xilong Wang,2 Qikuan Hu,3,7 Hechun Xia,2 Gaoyang Qi,1,2 Jinsong Wu,4 Hui Ma2 1Clinical Medicine College, Ningxia Medical University, 2Department of Neurosurgery, General Hospital of Ningxia Medical University, 3Ningxia Key Laboratory of Cerebrocranial Diseases, The National Key Laboratory Incubation Base, Yinchuan, 4Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, 5Department of Radiology, General Hospital of Ningxia Medical University, Yinchuan, People’s Republic of China; 6Department of Neuroscience and Cell Biology, Robert Wood Johnson Medical School of Rutgers University, Piscataway, NJ, USA; 7Department of Physiology, Ningxia Medical University, Yinchuan, People’s Republic of China *These authors contributed equally to this work Objective: This study investigated the correlation between choline/creatine (Cho/Cr ratios determined by multivoxel proton magnetic resonance spectroscopy (1H-MRS and the distribution of cancer stem-like cells (CSLCs in high-grade gliomas. Patients and methods: Sixteen patients with high-grade gliomas were recruited and underwent 1H-MRS examination before surgery to identify distinct tumor regions with variable Cho/Cr ratios. Using intraoperative neuronavigation, tumor tissues were accurately sampled from regions with high and low Cho/Cr ratios within each tumor. The distribution of CSLCs in samples from glioma tissue regions with different Cho/Cr ratios was quantified by neurosphere culture, immunohistochemistry, and Western blot. Results: The mean neurosphere formation rate in tissues with high Cho/Cr ratios was significantly increased compared with that in low Cho/Cr ratio tissues (13.94±5.94 per 100 cells vs 8.04±3.99 per 100 cells, P<0.001. Immunohistochemistry indicated that tissues with high Cho/Cr ratios had elevated expression of CD133, nestin, and CD15, relative to low Cho/Cr ratio tissue

Two new and one newly recorded species of Polypedilum Kieffer 1912 with DNA barcodes from Oriental China (Chironomidae: Diptera).

Science.gov (United States)

Yan, Chuncai; Song, Chao; Liu, Ting; Zhao, Guangjun; Hou, Ziyuan; Cao, Wei; Wang, Xinhua

2017-03-02

Polypedilum (Tripodura) enshiense Song & Wang sp. n. and P. (Tripodura) jianfengense Song & Wang sp. n. are described and illustrated as male imagines from China. P. (Uresipedilum) paraconvictum Yamamoto, Yamamoto & Hirowatari, 2016 is recorded from China for the first time. Cytochrome coxidase subunit I (COI) sequence of above species are uploaded to Barcode of Life Data Systems (BOLD).

Nomenclatural corrections to the taxonomic revision of The Old World species of Boehmeria (Urticaceae, tribus Boehmeriae) by Wilmot-Dear and Friis (2013)

DEFF Research Database (Denmark)

Wilmot-Dear, Christine Melanie; Friis, Ib; Govaerts, R. H. A.

2014-01-01

(H. Lév.) C.J. Chen in Chen et al. as the correct name for the variety named in the revision as B. zollingeriana Wedd. var. podocarpa (W.T. Wang) W.T. Wang & C.J. Chen in Chen et al., (3) that the combination B. spicata (Thunb.) Thunb., based on Urtica spicata Thunb., is not illegitimate, as stated...

Synthesis, Photophysical, Electrochemical and Thermal Studies of ...

Indian Academy of Sciences (India)

of Triarylamines based on benzo[g]quinoxalines. AZAM M ...... Son H-J, Han W-S, Wee K-R, Yoo D-H, Lee J-H, Kwon. S-N, Ko J ... Kim S K, Yang B, Park Y I, Ma Y J -Y and Lee H -J K ... M, Wang R-Y, Tao Y and Wang S 2004 J. Mater. Chem.

Theoretical Criteria for Scattering Dark States in Nanostructured Particles

Science.gov (United States)

2014-01-01

64, 023805. (39) Suh, W.; Wang, Z.; Fan, S. IEEE J. Quantum Electron. 2004, 40, 1511–1518. (40) Smith, D. D.; Chang, H.; Fuller, K. A.; Rosenberger...Mukherjee, S.; Mirin, N. A.; Levit , S. D.; Nordlander, P.; Halas, N. J. J. Phys. Chem. C 2010, 114, 7378–7383. 16 (60) Wang, M.; Cao, M.; Chen, X.; Gu

African Journal of Biotechnology - Vol 8, No 19 (2009)

African Journals Online (AJOL)

T Xie, A Wang, L Huang, H Li, Z Chen, Q Wang, X Yin ... M Babar, Y Saranga, Z Iqbal, M Arif, Y Zafar, E Lubbers, P Chee ... Evaluation of new generation maize steak virus (MSV) resistant maize varieties for adaptation to a southern guinea savanna ecology of Nigeria · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

Elevated Levels of Somatic Mutation as a Biomarker of Environmental Effects Contributing to Breast Carcinogenesis

Science.gov (United States)

2006-07-01

with early term pregnancy conferring a persistent protective effect [5]. Exposure to ionizing radiation, while a lifetime risk factor for breast cancer...lactational differentiation, such as occurs during term pregnancy , confers resistance to carcinogene- sis [26,27]. We have developed a novel human...anemia. Science 297, 606–609. 19. D’Andrea, A. D. and Grompe, M. (2003) The Fanconi anaemia /BRCA pathway. Nat. Rev. Cancer 3, 23–34. 20. Xia, F., Taghian

RP-HPLCdetermination of ginsenosides RG1 and RB1 in Panax ...

African Journals Online (AJOL)

Y Liu, Q He, D Liu, W Wan, X Liu, C Wen, W Fang, W Zhou, Z Xia ... RP-HPLC method is adopted, column used is a ZOBAX SB-C18 column (4.6 mm × 250 mnl, 5 μm), mobile phase A is water, and B is acetonitrile, gradient elution conditions are: 0~20 min (A:B 20:80), 20~60 min (A:B 20~35: 80~65); and detection ...

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African Journals Online (AJOL)

Items 651 - 700 of 1323 ... L Wang, X Wang, J Zhang, Z Yang, Y Liu, D Cui, Z Qin, J Meng, X Kong, ... and wound healing activity of the fruits of Amorpha fruticosa l. ... antioxidant activities and phenolic constituents of field-grown and in ... Vol 14, No 3 (2017), Evaluation of crude flaxseed (Linum usitatissimum L.) oil in burn ...

DNA characterization and polymorphism of KISS1 gene in Egyptian ...

African Journals Online (AJOL)

Aghomotsegin

2015-07-29

Jul 29, 2015 ... effect on litter size performance and many studies were carried out to identify ... gene (Wang et al., 2011), kit ligand (KITLG) gene (An et al., 2012) and bone ..... An XP, Han P, HouJX, Zhao HB, Yan Y, Ma T, Fang F, MengFX, Song. YX, Wang JG ... Chu MX, Zhao XH, Zhang YJ, Jin M (2010). Polymorphisms ...

Overcoming Endocrine Resistance by Targeting ER/FoxA1/IL-8 Axis

Science.gov (United States)

2015-10-01

Creighton, Fugen Li, Martin Shea, Agostina Nardone, Tao Wang, Laura M. Heiser , Pavana Anur, Nicholas Wang, Catie Grasso, Paul Spellman, Carolina...Xiaoyong Fu, Rinath Jeselsohn, Resel Pereira, Emporia F. Hollingsworth, Chad J. Creighton, Fugen Li, Martin Shea, Agostina Nardone, Laura M. Heiser , Pavana...Rinath Jeselsohn, Emporia F. Hollingsworth, Dolores Lopez-Terrada, Chad J. Creighton, Agostina Nardone, Martin Shea, Laura M. Heiser , Pavana Anur

Control of Boundary Layers for Aero-optical Applications

Science.gov (United States)

2015-06-23

with some difficulty) from hot-wire velocity measurements, or computed directly from CFD results (e.g. Wang & Wang, 2012). Several different density...of experimental and computational research, especially applied to supersonic and hypersonic boundary layers; see Smits & Dussauge (1996), Spina et...Duan, L., Beekman, I. and Martin, M.P. (2010) Direct Numerical Simulation of Hypersonic Turbulent Boundary Layers. Part 2. Effect of Wall

Phonology Is Necessary, but Not Sufficient: A Rejoinder

Science.gov (United States)

Paul, Peter V.; Wang, Ye; Trezek, Beverly J.; Luckner, John L.

2009-01-01

Paul, Wang, Trezek, and Luckner offer a rebuttal to an article by Allen, Clark, del Giudice, Koo, Lieberman, Mayberry, and Miller published in the same issue of the "American Annals of the Deaf" (Fall 2009) that is critical of an article by Wang, Trezek, Luckner, and Paul that was published in the Fall 2008 "Annals". Major themes from the article…

Prognostic and predictive biomarkers for hypoxic regions on breast cancer: advances and challenges Biomarcadores preditivos e prognósticos em regiões hipóxicas do câncer de mama: avanços e desafios

Directory of Open Access Journals (Sweden)

Moacyr Jesus Barreto de Melo Rêgo

2013-02-01

Full Text Available Hypoxia has been extensively studied in solid tumors mainly in breast cancers and it is commonly associated with chemotherapy and radiotherapy resistance. Hypoxia inducible factor (HIF-1α is responsible for hypoxia in the tumor microenvironment and its molecular mechanisms as well as its therapeutic strategies have been described. However, a few investigations in the literature deal with its role in the hypoxic environment at diagnosis with the aim to guide therapeutic approaches. This study alerts researchers in pathology and oncology to the importance of assessing area extension as well as specific biomarkers, inasmuch as molecules reactive to hypoxia may indicate response to antiangiogenic therapy. The extension of hypoxic areas may alter the choice of therapeutic approach, insofar as some antiangiogenic treatments may considerably aggravate patient's clinical course since they create a hypoxic environment.A hipóxia vem sendo bastante estudada nos tumores sólidos, principalmente nos de mama, os quais são frequentemente responsáveis pela resistência a quimioterapia e radioterapia. O hypoxia inducible factor (HIF-1α é o principal responsável pela hipóxia no microambiente tumoral e seus mecanismos moleculares têm sido descritos, além de estratégias terapêuticas desenhadas para essa molécula. Porém, poucos estudos na literatura tratam do papel do microambiente hipóxico no momento do diagnóstico para colaborar com a conduta dos oncologistas. Este artigo alerta os pesquisadores em patologia e oncologia para que eles observem a importância da avaliação da extensão da área, bem como dos biomarcadores específicos para esse ambiente, já que moléculas responsivas à hipóxia podem ser indicativas de resposta à terapia antiangiogênica. A extensão das áreas hipóxicas pode mudar a decisão do oncologista na escolha da conduta terapêutica, visto que alguns tratamentos antiangiogênicos podem piorar consideravelmente a evolu

Hybridizing scholastic psychology with Chinese medicine: a seventeenth-century Chinese Catholic's conceptions of xin (mind and heart).

Science.gov (United States)

Zhang, Qiong

2008-01-01

This paper explores the dynamics of cultural interactions between early modern China and Europe initiated by the Jesuits and other Catholic missionaries through a case study of Wang Honghan, a seventeenth-century Chinese Catholic who systematically sought to integrate European learning introduced by the missionaries with pre-modern Chinese medicine. Focusing on the ways in which Wang combined his Western and Chinese sources to develop and articulate his views on xin (mind and heart), this paper argues that Wang arrived at a peculiar hybrid between scholastic psychology and Chinese medicine, not so much through a course of haphazard misunderstanding as through his conscious and patterned use and abuse of his Western sources, which was motivated most possibly by a wish to define a theoretical position that most suited his social roles as a Catholic convert and a Chinese medical doctor. Thus, rather than seeing Wang as an epitome of"transmission failure," this paper offers it as a showcase for the tremendous dynamism and creativity occurring at this East-West "contact zone as representatives of both cultures sought to appropriate and transform the symbolic and textual resources of the other side.

Efficient and Anonymous Authentication Scheme for Wireless Body Area Networks.

Science.gov (United States)

Wu, Libing; Zhang, Yubo; Li, Li; Shen, Jian

2016-06-01

As a significant part of the Internet of Things (IoT), Wireless Body Area Network (WBAN) has attract much attention in this years. In WBANs, sensors placed in or around the human body collect the sensitive data of the body and transmit it through an open wireless channel in which the messages may be intercepted, modified, etc. Recently, Wang et al. presented a new anonymous authentication scheme for WBANs and claimed that their scheme can solve the security problems in the previous schemes. Unfortunately, we demonstrate that their scheme cannot withstand impersonation attack. Either an adversary or a malicious legal client could impersonate another legal client to the application provider. In this paper, we give the detailed weakness analysis of Wang et al.'s scheme at first. Then we present a novel anonymous authentication scheme for WBANs and prove that it's secure under a random oracle model. At last, we demonstrate that our presented anonymous authentication scheme for WBANs is more suitable for practical application than Wang et al.'s scheme due to better security and performance. Compared with Wang et al.'s scheme, the computation cost of our scheme in WBANs has reduced by about 31.58%.

A re-examination of the effect of contextual group size on people's attitude to risk

Directory of Open Access Journals (Sweden)

Kazumi Shimizu

2011-02-01

Full Text Available Using Kahneman and Tversky's life-death decision paradigm, Wang and colleagues (e.g., Wang and Johnston, 1995; Wang, 1996a, 1996b, 1996c, 2008; Wang et al., 2001 have shown two characteristic phenomena regarding people's attitude to risk when the contextual group size is manipulated. In both positive and negative frames, people tend to take greater risks in life-death decisions as the contextual group size becomes smaller; this risk-seeking attitude is greater when framed positively than negatively. (This second characteristic often leads to the disappearance of the framing effect in small group contexts comprising of 6 or 60 people. Their results could shed new light on the effect of contextual group size on people's risk choice. However these results are usually observed in laboratory experiments with university student samples. This study aims to examine the external validity of these results through different ways of experimentation and with a different sample base. The first characteristic was replicated in both a face-to-face interview with a randomly selected sample of the Japanese general public, and a web-based experiment with a non-student sample, but not the second.

Risk and Resiliency for Dementia: Comparison of Male and Female Veterans

Science.gov (United States)

2017-09-01

5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER Kristine Yaffe, MD 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME...Identifier (e.g. ORCID ID): n/a Nearest person month worked : 2 Contribution to Project: Ms. Xia performs the data analyses for this project. Funding...Supporting Agency: NIH Performance Period: 10/01/16-09/30/17 Level of Funding: $499,643 Title: Women , Trauma and Eating (PI: Maguen

Prognosis of Lung Cancer: Heredity or Environment

Science.gov (United States)

2015-06-01

and white patients in an equal access health system. Cancer Epidemiol Biomarkers Prev 2012;21:1841–1847. 19. Hardy D, Xia R, Liu CC, Cormier JN...Nurgalieva Z, Du XL. Racial dis- parities and survival for nonsmall-cell lung cancer in a large cohort of black and white elderly patients. Cancer 2009;115...P. In lung cancer patients, age, race-ethnicity, gender and smoking predict adverse comor- bidity, which in turn predicts treatment and survival. J

Using Software Applications to Facilitate and Enhance Strategic Planning

Science.gov (United States)

1993-09-01

Angeles, CA 90089-0021 213-743-3083 XIA 2.0 Booz-Allen & Hamilton, Inc. 1953 Gallows Road Vienna, VA 11180 703-893-0040 92 REFERENCES Ansoff , H. Igor ...to doing business was invented ( Ansoff 1984). Two examples of business applications of strategy are generic and competitive strategies (Mintzberg 1991...34 ( Ansoff 1984, p. 188) Keller (1990) states the purpose of the PPBS was "to produce a plan, a program, and, finally a budget for the Department of Defense

High Efficiency Flexible Battery Based on Graphene-carbon Nanotube Hybrid Structure

Science.gov (United States)

2015-02-26

Choi, Carbon 77 1065(2014) 2. Hierarchical NiCo2O4@nickel-sulfide nanoplate arrays for high-performance supercapacitors , Chu Q, Wang W, Wang X...Graphene:Synthesis and Applications, CRC Press ISBN-10: 1439861870 | ISBN-13: 978-1439861875 | Publication Date: October 11, 2011 Handbook of Nanomaterials ...Properties, Carbon Nanomaterials : a review, Nitin Choudhary, Sookhyun Hwang, Wonbong Choi, Springer (2013) 15. Santanu Das and Wonbong Choi, Graphene

Extended-Range Prediction with Low-Dimensional, Stochastic-Dynamic Models: A Data-driven Approach

Science.gov (United States)

2013-09-30

statistically extratropical storms and extremes, and link these to LFV modes. Mingfang Ting, Yochanan Kushnir, Andrew W. Robertson, Lei Wang...forecast models, as well as in the understanding they have generated. Adam Sobel, Daehyun Kim and Shuguang Wang. Extratropical variability and...predictability. Determine the extent to which extratropical monthly and seasonal low-frequency variability (LFV, i.e. PNA, NAO, as well as other regional

Toxicity evaluation of boron nitride nanospheres and water-soluble boron nitride in Caenorhabditis elegans

Directory of Open Access Journals (Sweden)

Wang N

2017-08-01

Full Text Available Ning Wang,1 Hui Wang,2 Chengchun Tang,3 Shijun Lei,1 Wanqing Shen,1 Cong Wang,1 Guobin Wang,4 Zheng Wang,1,4 Lin Wang1,5 1Research Center for Tissue Engineering and Regenerative Medicine, Union Hospital, 2Department of Medical Genetics, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 3Boron Nitride Research Center, School of Materials Science and Engineering, Hebei University of Technology, Tianjin, 4Department of Gastrointestinal Surgery, 5Department of Clinical Laboratory, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Abstract: Boron nitride (BN nanomaterials have been increasingly explored for potential biological applications. However, their toxicity remains poorly understood. Using Caenorhabditis elegans as a whole-animal model for toxicity analysis of two representative types of BN nanomaterials – BN nanospheres (BNNSs and highly water-soluble BN nanomaterial (named BN-800-2 – we found that BNNSs overall toxicity was less than soluble BN-800-2 with irregular shapes. The concentration thresholds for BNNSs and BN-800-2 were 100 µg·mL-1 and 10 µg·mL-1, respectively. Above this concentration, both delayed growth, decreased life span, reduced progeny, retarded locomotion behavior, and changed the expression of phenotype-related genes to various extents. BNNSs and BN-800-2 increased oxidative stress levels in C. elegans by promoting reactive oxygen species production. Our results further showed that oxidative stress response and MAPK signaling-related genes, such as GAS1, SOD2, SOD3, MEK1, and PMK1, might be key factors for reactive oxygen species production and toxic responses to BNNSs and BN-800-2 exposure. Together, our results suggest that when concentrations are lower than 10 µg·mL-1, BNNSs are more biocompatible than BN-800-2 and are potentially biocompatible material. Keywords: boron nitride nanomaterials, Caenorhabditis elegans, nanotoxicology

Equivalent construction of the infinitesimal time translation operator in algebraic dynamics algorithm for partial differential evolution equation

Institute of Scientific and Technical Information of China (English)

无

2010-01-01

We give an equivalent construction of the infinitesimal time translation operator for partial differential evolution equation in the algebraic dynamics algorithm proposed by Shun-Jin Wang and his students. Our construction involves only simple partial differentials and avoids the derivative terms of δ function which appear in the course of computation by means of Wang-Zhang operator. We prove Wang’s equivalent theorem which says that our construction and Wang-Zhang’s are equivalent. We use our construction to deal with several typical equations such as nonlinear advection equation, Burgers equation, nonlinear Schrodinger equation, KdV equation and sine-Gordon equation, and obtain at least second order approximate solutions to them. These equations include the cases of real and complex field variables and the cases of the first and the second order time derivatives.

MO-D-BRC-02: Auto-Planning

International Nuclear Information System (INIS)

Xia, P.

2016-01-01

Treatment planning is a central part of radiation therapy, including delineation in tumor volumes and critical organs, setting treatment goals of prescription doses to the tumor targets and tolerance doses to the critical organs, and finally generation of treatment plans to meet the treatment goals. National groups like RTOG have led the effort to standardize treatment goals of the prescription doses to the tumor targets and tolerance doses to the critical organs based on accumulated knowledge from decades of abundant clinical trial experience. The challenge for each clinical department is how to achieve or surpass these set goals within the time constraints of clinical practice. Using fifteen testing cases from different treatment sites such as head and neck, prostate with and without pelvic lymph nodes, SBRT spine, we will present clinically utility of advanced planning tools, including knowledge based, automatic based, and multiple criteria based tools that are clinically implemented. The objectives of this session are: Understand differences among these three advanced planning tools Provide clinical assessments on the utility of the advanced planning tools Discuss clinical challenges of treatment planning with large variations in tumor volumes and their relationships with adjacent critical organs. Ping Xia received research grant from Philips. Jackie Wu received research grant from Varian; P. Xia, Research support by Philips and Varian; Q. Wu, NIH, Varian Medical

MO-D-BRC-00: In Memoriam of Jan Van De Geijn: Knowledge-Based Planning

International Nuclear Information System (INIS)

2016-01-01

Treatment planning is a central part of radiation therapy, including delineation in tumor volumes and critical organs, setting treatment goals of prescription doses to the tumor targets and tolerance doses to the critical organs, and finally generation of treatment plans to meet the treatment goals. National groups like RTOG have led the effort to standardize treatment goals of the prescription doses to the tumor targets and tolerance doses to the critical organs based on accumulated knowledge from decades of abundant clinical trial experience. The challenge for each clinical department is how to achieve or surpass these set goals within the time constraints of clinical practice. Using fifteen testing cases from different treatment sites such as head and neck, prostate with and without pelvic lymph nodes, SBRT spine, we will present clinically utility of advanced planning tools, including knowledge based, automatic based, and multiple criteria based tools that are clinically implemented. The objectives of this session are: Understand differences among these three advanced planning tools Provide clinical assessments on the utility of the advanced planning tools Discuss clinical challenges of treatment planning with large variations in tumor volumes and their relationships with adjacent critical organs. Ping Xia received research grant from Philips. Jackie Wu received research grant from Varian; P. Xia, Research support by Philips and Varian; Q. Wu, NIH, Varian Medical

Frequency and pattern of Chinese herbal medicine prescriptions for chronic hepatitis in Taiwan.

Science.gov (United States)

Chen, Fang-Pey; Kung, Yen-Ying; Chen, Yu-Chun; Jong, Maw-Shiou; Chen, Tzeng-Ji; Chen, Fun-Jou; Hwang, Shinn-Jang

2008-04-17

Chinese herbal medicine (CHM) has been commonly used in treating liver diseases in Asian countries. To conduct a large-scale pharmacoepidemiological study and evaluate the frequency and pattern of CHM prescriptions in treating chronic hepatitis. We obtained the database of traditional Chinese medicine outpatient claims from the national health insurance in Taiwan for the whole 2002. Patients with chronic hepatitis were identified by the corresponding diagnosis of International Classification of Disease among claimed visiting files. Corresponding prescription files were analyzed, and association rule were applied to evaluate the co-prescription of CHM in treating chronic hepatitis. Among the 91,080 subjects treated by CHM for chronic hepatitis, the peak age was in the 40 s, followed by 30 s and 50 s. Male/female ratio was 2.07:1. Long-dan-xie-gan-tang and Saliva miltiorrhiza (Dan-shen) were the most commonly prescribed Chinese herbal formula and single herbal drug, respectively. The most common two-drug prescription was Jia-wei-xia-yao-san plus Saliva miltiorrhiza, and the most common three-drug prescription was Jia-wei-xia-yao-san plus Saliva miltiorrhiza and Artemisia capillaries (Yin-chen-hao). This study showed the utilization pattern of Chinese herbal drugs or formulae in treating chronic hepatitis. Further researches and clinical trials are needed to evaluate the efficacy of these Chinese herbs or its ingredients in treating chronic hepatitis.

Water organic pollution and eutrophication influence soil microbial processes, increasing soil respiration of estuarine wetlands: site study in jiuduansha wetland.

Science.gov (United States)

Zhang, Yue; Wang, Lei; Hu, Yu; Xi, Xuefei; Tang, Yushu; Chen, Jinhai; Fu, Xiaohua; Sun, Ying

2015-01-01

Undisturbed natural wetlands are important carbon sinks due to their low soil respiration. When compared with inland alpine wetlands, estuarine wetlands in densely populated areas are subjected to great pressure associated with environmental pollution. However, the effects of water pollution and eutrophication on soil respiration of estuarine and their mechanism have still not been thoroughly investigated. In this study, two representative zones of a tidal wetland located in the upstream and downstream were investigated to determine the effects of water organic pollution and eutrophication on soil respiration of estuarine wetlands and its mechanism. The results showed that eutrophication, which is a result of there being an excess of nutrients including nitrogen and phosphorus, and organic pollutants in the water near Shang shoal located upstream were higher than in downstream Xia shoal. Due to the absorption and interception function of shoals, there to be more nitrogen, phosphorus and organic matter in Shang shoal soil than in Xia shoal. Abundant nitrogen, phosphorus and organic carbon input to soil of Shang shoal promoted reproduction and growth of some highly heterotrophic metabolic microorganisms such as β-Proteobacteria, γ-Proteobacteria and Acidobacteria which is not conducive to carbon sequestration. These results imply that the performance of pollutant interception and purification function of estuarine wetlands may weaken their carbon sequestration function to some extent.

MO-D-BRC-04: Multiple-Criteria Optimization Planning

International Nuclear Information System (INIS)

Donaghue, J.

2016-01-01

Treatment planning is a central part of radiation therapy, including delineation in tumor volumes and critical organs, setting treatment goals of prescription doses to the tumor targets and tolerance doses to the critical organs, and finally generation of treatment plans to meet the treatment goals. National groups like RTOG have led the effort to standardize treatment goals of the prescription doses to the tumor targets and tolerance doses to the critical organs based on accumulated knowledge from decades of abundant clinical trial experience. The challenge for each clinical department is how to achieve or surpass these set goals within the time constraints of clinical practice. Using fifteen testing cases from different treatment sites such as head and neck, prostate with and without pelvic lymph nodes, SBRT spine, we will present clinically utility of advanced planning tools, including knowledge based, automatic based, and multiple criteria based tools that are clinically implemented. The objectives of this session are: Understand differences among these three advanced planning tools Provide clinical assessments on the utility of the advanced planning tools Discuss clinical challenges of treatment planning with large variations in tumor volumes and their relationships with adjacent critical organs. Ping Xia received research grant from Philips. Jackie Wu received research grant from Varian; P. Xia, Research support by Philips and Varian; Q. Wu, NIH, Varian Medical

MO-D-BRC-01: Memorial Lecture

International Nuclear Information System (INIS)

Fraass, B.

2016-01-01

Treatment planning is a central part of radiation therapy, including delineation in tumor volumes and critical organs, setting treatment goals of prescription doses to the tumor targets and tolerance doses to the critical organs, and finally generation of treatment plans to meet the treatment goals. National groups like RTOG have led the effort to standardize treatment goals of the prescription doses to the tumor targets and tolerance doses to the critical organs based on accumulated knowledge from decades of abundant clinical trial experience. The challenge for each clinical department is how to achieve or surpass these set goals within the time constraints of clinical practice. Using fifteen testing cases from different treatment sites such as head and neck, prostate with and without pelvic lymph nodes, SBRT spine, we will present clinically utility of advanced planning tools, including knowledge based, automatic based, and multiple criteria based tools that are clinically implemented. The objectives of this session are: Understand differences among these three advanced planning tools Provide clinical assessments on the utility of the advanced planning tools Discuss clinical challenges of treatment planning with large variations in tumor volumes and their relationships with adjacent critical organs. Ping Xia received research grant from Philips. Jackie Wu received research grant from Varian; P. Xia, Research support by Philips and Varian; Q. Wu, NIH, Varian Medical

MO-D-BRC-03: Knowledge-Based Planning

International Nuclear Information System (INIS)

Wu, Q.

2016-01-01

Treatment planning is a central part of radiation therapy, including delineation in tumor volumes and critical organs, setting treatment goals of prescription doses to the tumor targets and tolerance doses to the critical organs, and finally generation of treatment plans to meet the treatment goals. National groups like RTOG have led the effort to standardize treatment goals of the prescription doses to the tumor targets and tolerance doses to the critical organs based on accumulated knowledge from decades of abundant clinical trial experience. The challenge for each clinical department is how to achieve or surpass these set goals within the time constraints of clinical practice. Using fifteen testing cases from different treatment sites such as head and neck, prostate with and without pelvic lymph nodes, SBRT spine, we will present clinically utility of advanced planning tools, including knowledge based, automatic based, and multiple criteria based tools that are clinically implemented. The objectives of this session are: Understand differences among these three advanced planning tools Provide clinical assessments on the utility of the advanced planning tools Discuss clinical challenges of treatment planning with large variations in tumor volumes and their relationships with adjacent critical organs. Ping Xia received research grant from Philips. Jackie Wu received research grant from Varian; P. Xia, Research support by Philips and Varian; Q. Wu, NIH, Varian Medical

MO-D-BRC-01: Memorial Lecture

Energy Technology Data Exchange (ETDEWEB)

Fraass, B. [Cedars Sinai Medical Center (United States)

2016-06-15

Treatment planning is a central part of radiation therapy, including delineation in tumor volumes and critical organs, setting treatment goals of prescription doses to the tumor targets and tolerance doses to the critical organs, and finally generation of treatment plans to meet the treatment goals. National groups like RTOG have led the effort to standardize treatment goals of the prescription doses to the tumor targets and tolerance doses to the critical organs based on accumulated knowledge from decades of abundant clinical trial experience. The challenge for each clinical department is how to achieve or surpass these set goals within the time constraints of clinical practice. Using fifteen testing cases from different treatment sites such as head and neck, prostate with and without pelvic lymph nodes, SBRT spine, we will present clinically utility of advanced planning tools, including knowledge based, automatic based, and multiple criteria based tools that are clinically implemented. The objectives of this session are: Understand differences among these three advanced planning tools Provide clinical assessments on the utility of the advanced planning tools Discuss clinical challenges of treatment planning with large variations in tumor volumes and their relationships with adjacent critical organs. Ping Xia received research grant from Philips. Jackie Wu received research grant from Varian; P. Xia, Research support by Philips and Varian; Q. Wu, NIH, Varian Medical.

MO-D-BRC-02: Auto-Planning

Energy Technology Data Exchange (ETDEWEB)

Xia, P. [The Cleveland Clinic Foundation (United States)

2016-06-15

Treatment planning is a central part of radiation therapy, including delineation in tumor volumes and critical organs, setting treatment goals of prescription doses to the tumor targets and tolerance doses to the critical organs, and finally generation of treatment plans to meet the treatment goals. National groups like RTOG have led the effort to standardize treatment goals of the prescription doses to the tumor targets and tolerance doses to the critical organs based on accumulated knowledge from decades of abundant clinical trial experience. The challenge for each clinical department is how to achieve or surpass these set goals within the time constraints of clinical practice. Using fifteen testing cases from different treatment sites such as head and neck, prostate with and without pelvic lymph nodes, SBRT spine, we will present clinically utility of advanced planning tools, including knowledge based, automatic based, and multiple criteria based tools that are clinically implemented. The objectives of this session are: Understand differences among these three advanced planning tools Provide clinical assessments on the utility of the advanced planning tools Discuss clinical challenges of treatment planning with large variations in tumor volumes and their relationships with adjacent critical organs. Ping Xia received research grant from Philips. Jackie Wu received research grant from Varian; P. Xia, Research support by Philips and Varian; Q. Wu, NIH, Varian Medical.

MO-D-BRC-04: Multiple-Criteria Optimization Planning

Energy Technology Data Exchange (ETDEWEB)

Donaghue, J. [Akron General Medical Center (United States)

2016-06-15

Treatment planning is a central part of radiation therapy, including delineation in tumor volumes and critical organs, setting treatment goals of prescription doses to the tumor targets and tolerance doses to the critical organs, and finally generation of treatment plans to meet the treatment goals. National groups like RTOG have led the effort to standardize treatment goals of the prescription doses to the tumor targets and tolerance doses to the critical organs based on accumulated knowledge from decades of abundant clinical trial experience. The challenge for each clinical department is how to achieve or surpass these set goals within the time constraints of clinical practice. Using fifteen testing cases from different treatment sites such as head and neck, prostate with and without pelvic lymph nodes, SBRT spine, we will present clinically utility of advanced planning tools, including knowledge based, automatic based, and multiple criteria based tools that are clinically implemented. The objectives of this session are: Understand differences among these three advanced planning tools Provide clinical assessments on the utility of the advanced planning tools Discuss clinical challenges of treatment planning with large variations in tumor volumes and their relationships with adjacent critical organs. Ping Xia received research grant from Philips. Jackie Wu received research grant from Varian; P. Xia, Research support by Philips and Varian; Q. Wu, NIH, Varian Medical.

MO-D-BRC-00: In Memoriam of Jan Van De Geijn: Knowledge-Based Planning

Energy Technology Data Exchange (ETDEWEB)

NONE

2016-06-15

Treatment planning is a central part of radiation therapy, including delineation in tumor volumes and critical organs, setting treatment goals of prescription doses to the tumor targets and tolerance doses to the critical organs, and finally generation of treatment plans to meet the treatment goals. National groups like RTOG have led the effort to standardize treatment goals of the prescription doses to the tumor targets and tolerance doses to the critical organs based on accumulated knowledge from decades of abundant clinical trial experience. The challenge for each clinical department is how to achieve or surpass these set goals within the time constraints of clinical practice. Using fifteen testing cases from different treatment sites such as head and neck, prostate with and without pelvic lymph nodes, SBRT spine, we will present clinically utility of advanced planning tools, including knowledge based, automatic based, and multiple criteria based tools that are clinically implemented. The objectives of this session are: Understand differences among these three advanced planning tools Provide clinical assessments on the utility of the advanced planning tools Discuss clinical challenges of treatment planning with large variations in tumor volumes and their relationships with adjacent critical organs. Ping Xia received research grant from Philips. Jackie Wu received research grant from Varian; P. Xia, Research support by Philips and Varian; Q. Wu, NIH, Varian Medical.

MO-D-BRC-03: Knowledge-Based Planning

Energy Technology Data Exchange (ETDEWEB)

Wu, Q. [Duke University Medical Center (United States)

2016-06-15

Treatment planning is a central part of radiation therapy, including delineation in tumor volumes and critical organs, setting treatment goals of prescription doses to the tumor targets and tolerance doses to the critical organs, and finally generation of treatment plans to meet the treatment goals. National groups like RTOG have led the effort to standardize treatment goals of the prescription doses to the tumor targets and tolerance doses to the critical organs based on accumulated knowledge from decades of abundant clinical trial experience. The challenge for each clinical department is how to achieve or surpass these set goals within the time constraints of clinical practice. Using fifteen testing cases from different treatment sites such as head and neck, prostate with and without pelvic lymph nodes, SBRT spine, we will present clinically utility of advanced planning tools, including knowledge based, automatic based, and multiple criteria based tools that are clinically implemented. The objectives of this session are: Understand differences among these three advanced planning tools Provide clinical assessments on the utility of the advanced planning tools Discuss clinical challenges of treatment planning with large variations in tumor volumes and their relationships with adjacent critical organs. Ping Xia received research grant from Philips. Jackie Wu received research grant from Varian; P. Xia, Research support by Philips and Varian; Q. Wu, NIH, Varian Medical.

Parâmetros astrofísicos de estrelas gigantes do aglomerado globular 47 Tucanae

Science.gov (United States)

Alves-Brito, A.; Barbuy, B.

2003-08-01

Os aglomerados globulares são considerados laboratórios astrofísicos para a verificação da teoria de evolução estelar, bem como a trajetória químio-dinâmica das galáxias hospedeiras. Em particular, 47 Tucanae (NGC 104) configura-se como um dos mais extensivamente estudados aglomerados globulares da Galáxia devido a relativa proximidade ao Sol (R¤ = 4.5 kpc) e alta latitute galáctica (b = -44°,89). Neste trabalho, apresentamos a velocidade radial heliocêntrica e os parâmetros atmosféricos (Teff, logg, [Fe/H]) de 5 estrelas gigantes do aglomerado globular 47 Tucanae. Os espectros foram obtidos pelo espectrógrafo UVES (Ultaviolet Visual Echelle Spectrograph) de alta resolução (R = 60000) e alta razão sinal-ruído (S/N > 200), acoplado ao telescópio de 8,2m Kueyen do VLT (Very Large Telescope). Nós encontramos = -22,43 +/- 3,97 km/s, [Fe/H] ~ -0.7, 1,2 estrelas cobrem um intervalo de magnitude 12,2 < V < 14,2. Os parâmetros atmosféricos são fundamentais para a construção de espectros sintéticos de outros aglomerados globulares ricos em metais. Trabalho financiado pela FAPESP e pelo CNPq.

Active Learning for Automatic Audio Processing of Unwritten Languages (ALAPUL)

Science.gov (United States)

2016-07-01

AFRL-RH-WP-TR-2016-0074 ACTIVE LEARNING FOR AUTOMATIC AUDIO PROCESSING OF UNWRITTEN LANGUAGES (ALAPUL) Dimitra Vergyri Andreas Kathol Wen Wang...FA8650-15-C-9101 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) *Dimitra Vergyri; Andreas Kathol; Wen Wang; Chris Bartels; Julian VanHout...feature transform through deep auto-encoders for better phone recognition performance. We target iterative learning to improve the system through

Overcoming Endocrine Resistance by Targeting ER/FoxA1/IL 8 Axis

Science.gov (United States)

2016-10-01

Nardone, Carmine De Angelis, Laura M. Heiser , Pavana Anur, Nicholas Wang, Catherine S. Grasso, Paul Spellman, Obi L. Griffith, Anna Tsimelzon...presentations Publications Fu X, Jeselsohn R, Pereira R, Hollingsworth EF, Creighton CJ, Li F, Shea M, Nardone A, Angelis CD, Heiser LM, Anur P, Wang N...performed the bioinformatics analysis of RNA-Seq and ChIP-Seq data. Name: Laura Heiser Project Role: Collaborator Nearest person month worked: 1

Quantitative trait locus (QTL) mapping for 100-kernel weight of ...

African Journals Online (AJOL)

hope&shola

2010-12-06

Dec 6, 2010 ... regimes. Xiao-Hong Liu1, Zu-Ping Zheng2*, Zhen-Bo Tan3, Zhong Li2 and Chuan He2 ... al., 2005; Liu et al., 2007; Wang et al., 2007a; Guo et al.,. 2008; Tang .... They could individually account for 12.63, 7.22, 4.47 and 14.47% of .... Liu ZH, Tang JH, Wei XY, Wang EL, Tian GW, Hu YM, Chen WC. (2007).

Multivalent Peptidomimetic Conjugates as Inhibitors of Androgen Receptor Function in Therapy Resistant Prostate Cancer

Science.gov (United States)

2016-10-01

Haugbro M, Imberg-Kazdan K, Logan SK, Kirshenbaum K, Garabedian MJ. Multivalent Peptoid Conjugates Which Overcome Enzalutamide Resistance in Prostate...attached documents Wang Y, Dehigaspitiya DC, Levine PM, Profit AA, Haugbro M, Imberg-Kazdan K, Logan SK, Kirshenbaum K, Garabedian MJ. Multivalent...Enzalutamide Resistance in Prostate Cancer Cells Yu Wang1, Dilani C. Dehigaspitiya2, Paul M. Levine2, Adam A. Profit3, Michael Haugbro2, Keren Imberg

Multivalent Peptidomimetic Conjugates as Inhibitors of Androgen Receptor Function in Therapy-Resistant Prostate Cancer

Science.gov (United States)

2016-10-01

K, Logan SK, Kirshenbaum K, Garabedian MJ. Multivalent Peptoid Conjugates Which Overcome Enzalutamide Resistance in Prostate Cancer Cells. Cancer...Wang Y, Dehigaspitiya DC, Levine PM, Profit AA, Haugbro M, Imberg-Kazdan K, Logan SK, Kirshenbaum K, Garabedian MJ. Multivalent Peptoid Conjugates...Prostate Cancer Cells Yu Wang1, Dilani C. Dehigaspitiya2, Paul M. Levine2, Adam A. Profit3, Michael Haugbro2, Keren Imberg-Kazdan4, Susan K. Logan1,5

Enhanced Androgen Signaling with Androgen Receptor Overexpression in the Osteoblast Lineage Controls Skeletal Turnover, Matrix Quality and Bone Architecture

Science.gov (United States)

2009-12-01

Fu , M. , and Pestell , R. ( 2006 ). Epigenetic regulation of nuclear steroid receptors . Biochem. Pharmacol. 72 , 1589 – 1596...2006;38:1289–1297. 21. Leader J, Wang C, Fu M, Pestell R. Epigenetic regulation of nuclear steroid receptors. Biochem Pharmacol 2006;72:1589–1596. 22...Nat Genet 2006;38:1289-97. 21. Leader J, Wang C, Fu M, Pestell R. Epigenetic regulation of nuclear steroid receptors. Biochem Pharmacol 2006;72

Research Laboratory of Electronics Annual Report Number 125.

Science.gov (United States)

1983-01-01

approximation for modeling underwater acoustics. The summers of 1983 and 1984 mark the beginning of a series of geophysical and acoustic experiments in the...conditions, modifications in an adaptive noise cancelling algorithm such as the Widrow- Hoff least mean square algorithm, allows one to still reduce the...Stephanie Brown, Fielding Kanbe, Hiroshi Vaidyanathan, A. Ganesh Buchinger, Fritz Kayoun, Pierre H. Wang, Hong.Ming Cerrillo, Manuel V. Konrad, Cristina Wang

Study of the Neurophysiology of Central Fatigue

Science.gov (United States)

2014-11-05

AGENCY NAME(S) AND ADDRESS (ES) U.S. Army Research Office P.O. Box 12211 Research Triangle Park, NC 27709-2211 cognitive, fatigue, fatigability...Fatigability in Parkinson Disease. Movement Disorders 2012;27:e6. 4. Wang C, Ding M, Kluger BM. High-density EEG study of cue-evoked preparatory...258. 3. Kluger B, Wang C, Proemsey J, Ding M. Neuronal Correlates of Executive Dysfunction and Fatigability in Parkinson Disease. Movement Disorders

Origin of the Wang-Sheeley-Arge solar wind model

Science.gov (United States)

Sheeley, Neil R., Jr.

2017-03-01

A correlation between solar wind speed at Earth and the amount of magnetic field line expansion in the corona was verified in 1989 using 22 years of solar and interplanetary observations. We trace the evolution of this relationship from its birth 15 years earlier in the Skylab era to its current use as a space weather forecasting technique. This paper is the transcript of an invited talk at the joint session of the Historical Astronomy Division and the Solar Physics Division of the American Astronomical Society during its 224th meeting in Boston, MA, on 3 June 2014.

What do the shadow rates tell us about future inflation?

OpenAIRE

Kuusela, Annika; Hännikäinen, Jari

2017-01-01

This paper investigates whether shadow interest rates contain predictive power for U.S. inflation in a data-rich environment. We find that shadow rates are useful leading indicators of inflation. Shadow rates contain substantial in-sample and out-of-sample predictive power for inflation in both the zero lower bound (ZLB) and non-ZLB periods. We find that the shadow rate suggested by Wu and Xia (2016) contains more information about future inflation than the shadow rate suggested by Krippner (...

Molecular Mechanisms Underlying Genomic Instability in Brca-Deficient Cells

Science.gov (United States)

2014-03-01

repair defects asso- ciated with downstream mediators of the HR reaction (e.g., XRCC2, BRCA2, or PALB2) (Bouwman et al., 2010; Bowman- Colin et al., 2013...and BRCA-mutated breast cancers. Nat. Struct. Mol. Biol. 17, 688–695. Bowman- Colin , C., Xia, B., Bunting, S., Klijn, C., Drost, R., Bouwman, P., Fine...chromosomes. It is thus surprising that cells use ‘quick and dirty ’ repair by NHEJ rather than the slower, more accurate repair by homologous recombination

The Earliest Chinese Proto-Porcelain Excavated from Kiln Sites: An Elemental Analysis

OpenAIRE

Li, Yu; Zhang, Bin; Cheng, Huansheng; Zheng, Jianming

2015-01-01

In June 2012, the Piaoshan kiln site was excavated in Huzhou, Zhejiang Province, which hitherto proved to be the earliest known Chinese proto-porcelain kiln. Judging from the decorative patterns of unearthed impressed stoneware and proto-porcelain sherds, the site was determined to date to the late Xia (c. 2070-c. 1600 BC), the first dynasty of China. Here, we report on proton-induced X-ray emission analyses of 118 proto-porcelain and 35 impressed stoneware sherds from Piaoshan and five subse...

Harvesting policy for a delayed stage-structured Holling II predator-prey model with impulsive stocking prey

International Nuclear Information System (INIS)

Jiao Jianjun; Meng Xinzhu; Chen Lansun

2009-01-01

A predator-prey model with a stage structure for the predator, which improves the assumption that each individual predator has the same ability to capture prey, is proposed by Wang et al. [Wang W, Mulone G, Salemi F, Salone V. Permanence and stability of a stage-structured predator-prey model. J Math Anal Appl 2001;262:499-528]. It is assumed that immature individuals and mature individuals of the predator are divided by a fixed age and that immature predators do not have the ability to attack prey. We do economic management behavior for Wang model [Wang et al., 2001] by continuous harvesting on predator and impulsive stocking on prey. Then, a delayed stage-structured Holling type II predator-prey model with impulsive stocking prey and continuous harvesting predator is established. It is also assumed that the predating products of the predator is only to increase its bearing ability. We obtain the sufficient conditions of the global attractivity of predator-extinction boundary periodic solution and the permanence of the system. Our results show that the behavior of impulsive stocking prey plays an important role for the permanence of the system, and provide tactical basis for the biological resource management. Further, the numerical analysis is also inserted to illuminate the dynamics of the system.

Psychometric properties of the Chinese version of the Self-Efficacy for Appropriate Medication Use Scale in patients with stroke

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Dong XF

2016-03-01

Full Text Available Xiao-fang Dong,1 Yan-jin Liu,2 Ai-xia Wang,1 Pei-hua Lv1 1Neurology Department, 2Nursing Department, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People’s Republic of China Background: It has been reported that stroke has a higher incidence and mortality rate in the People’s Republic of China compared to the global average. These conditions can be managed by proper medication use, but ensuring medication adherence is challenging.Objective: To translate the Self-Efficacy for Appropriate Medication Use Scale into Chinese and test its validity and reliability in patients with stroke.Methods: Instrument performances were measured from January 15, 2015 to April 28, 2015 on a convenience sample of 400 patients with stroke recruited at four neurology departments of the First Affiliated Hospital of Zhengzhou University. Questionnaires included the Chinese versions of the Self-Efficacy for Appropriate Medication Use Scale (C-SEAMS and the General Self-Efficacy Scale (C-GSE. Construct validity, convergent validity, internal consistency, and test–retest reliability were measured.Results: Item analysis showed that item-to-total correlations were in the range of 0.362–0.672. Exploratory factor analysis revealed two factors (which accounted for 60.862% of total variance, with factor loading ranging from 0.534 to 0.756. Confirmatory factor analysis was performed to support the results, with an acceptable fit (χ2=73.716; df=64; P<0.01; goodness-of-fit index =0.902; adjusted goodness-of-fit index =0.897; comparative fit index =0.865; root-mean-square error of approximation =0.058. The convergent validity of the C-SEAMS correlated well with the validated measure of the C-GSE in measuring self-efficacy (r=0.531, P<0.01. Good internal consistency (Cronbach’s alpha ranged from 0.826 to 0.915 and test–retest reliability (Pearson’s correlation coefficient r=0.642, P<0.01 were found.Conclusion: The C-SEAMS is a brief and

Clinical, pathological, and radiological characteristics of solitary ground-glass opacity lung nodules on high-resolution computed tomography

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Qiu ZX

2016-09-01

Full Text Available Zhi-Xin Qiu,1 Yue Cheng,1 Dan Liu,1 Wei-Ya Wang,2 Xia Wu,2 Wei-Lu Wu,2 Wei-Min Li1,2 1Department of Respiratory Medicine, 2Department of Pathology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China Background: Lung nodules are being detected at an increasing rate year by year with high-resolution computed tomography (HRCT being widely used. Ground-glass opacity nodule is one of the special types of pulmonary nodules that is confirmed to be closely associated with early stage of lung cancer. Very little is known about solitary ground-glass opacity nodules (SGGNs. In this study, we analyzed the clinical, pathological, and radiological characteristics of SGGNs on HRCT.Methods: A total of 95 resected SGGNs were evaluated with HRCT scan. The clinical, pathological, and radiological characteristics of these cases were analyzed.Results: Eighty-one adenocarcinoma and 14 benign nodules were observed. The nodules included 12 (15% adenocarcinoma in situ (AIS, 14 (17% minimally invasive adenocarcinoma (MIA, and 55 (68% invasive adenocarcinoma (IA. No patients with recurrence till date have been identified. The positive expression rates of anaplastic lymphoma kinase and ROS-1 (proto-oncogene tyrosine-protein kinase ROS were only 2.5% and 8.6%, respectively. The specificity and accuracy of HRCT of invasive lung adenocarcinoma were 85.2% and 87.4%. The standard uptake values of only two patients determined by 18F-FDG positron emission tomography/computed tomography (PET/CT were above 2.5. The size, density, shape, and pleural tag of nodules were significant factors that differentiated IA from AIS and MIA. Moreover, the size, shape, margin, pleural tag, vascular cluster, bubble-like sign, and air bronchogram of nodules were significant determinants for mixed ground-glass opacity nodules (all P<0.05.Conclusion: We analyzed the clinical, pathological, and radiological characteristics of SGGNs on HRCT and found that the size, density

Polyacrylonitrile nanofibers coated with silver nanoparticles using a modified coaxial electrospinning process

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Yu DG

2012-11-01

Full Text Available Deng-Guang Yu,1 Jie Zhou,2 Nicholas P Chatterton,3 Ying Li,1 Jing Huang,2 Xia Wang11School of Materials Science and Engineering, University of Shanghai for Science and Technology, Shanghai, People's Republic of China; 2School of Life Sciences, East China Normal University, Shanghai, People's Republic of China; 3Faculty of Life Sciences, London Metropolitan University, London, United KingdomBackground: The objective of this investigation was to develop a new class of antibacterial material in the form of nanofibers coated with silver nanoparticles (AgNPs using a modified coaxial electrospinning approach. Through manipulation of the distribution on the surface of nanofibers, the antibacterial effect of Ag can be improved substantially.Methods: Using polyacrylonitrile (PAN as the filament-forming polymer matrix, an electrospinnable PAN solution was prepared as the core fluid. A silver nitrate (AgNO3 solution was exploited as sheath fluid to carry out the modified coaxial electrospinning process under varied sheath-to-core flow rate ratios.Results: Scanning electron microscopy and transmission electron microscopy demonstrated that the sheath AgNO3 solution can take a role in reducing the nanofibers' diameters significantly, a sheath-to-core flow rate ratio of 0.1 and 0.2 resulting in PAN nanofibers with diameters of 380 ± 110 nm and 230 ± 70 nm respectively. AgNPs are well distributed on the surface of PAN nanofibers. The antibacterial experiments demonstrated that these nanofibers show strong antimicrobial activities against Bacillus subtilis Wb800, and Escherichia coli dh5α.Conclusion: Coaxial electrospinning with AgNO3 solution as sheath fluid not only facilitates the electrospinning process, providing nanofibers with reduced diameters, but also allows functionalization of the nanofibers through coating with functional ingredients, effectively ensuring that the active antibacterial component is on the surface of the material, which leads to

Presurgical EEG-fMRI in a complex clinical case with seizure recurrence after epilepsy surgery

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Zhang J

2013-07-01

Full Text Available Jing Zhang,1 Qingzhu Liu,2 Shanshan Mei,2 Xiaoming Zhang,2 Xiaofei Wang,2 Weifang Liu,1 Hui Chen,1 Hong Xia,1 Zhen Zhou,1 Yunlin Li2 1School of Biomedical Engineering, Capital Medical University, Beijing, People's Republic of China; 2Department of Functional Neurology and Neurosurgery, Beijing Haidian Hospital, Beijing, People's Republic of China Abstract: Epilepsy surgery has improved over the last decade, but non-seizure-free outcome remains at 10%–40% in temporal lobe epilepsy (TLE and 40%–60% in extratemporal lobe epilepsy (ETLE. This paper reports a complex multifocal case. With a normal magnetic resonance imaging (MRI result and nonlocalizing electroencephalography (EEG findings (bilateral TLE and ETLE, with more interictal epileptiform discharges [IEDs] in the right frontal and temporal regions, a presurgical EEG-functional MRI (fMRI was performed before the intraoperative intracranial EEG (icEEG monitoring (icEEG with right hemispheric coverage. Our previous EEG-fMRI analysis results (IEDs in the left hemisphere alone were contradictory to the EEG and icEEG findings (IEDs in the right frontal and temporal regions. Thus, the EEG-fMRI data were reanalyzed with newly identified IED onsets and different fMRI model options. The reanalyzed EEG-fMRI findings were largely concordant with those of EEG and icEEG, and the failure of our previous EEG-fMRI analysis may lie in the inaccurate identification of IEDs and wrong usage of model options. The right frontal and temporal regions were resected in surgery, and dual pathology (hippocampus sclerosis and focal cortical dysplasia in the extrahippocampal region was found. The patient became seizure-free for 3 months, but his seizures restarted after antiepileptic drugs (AEDs were stopped. The seizures were not well controlled after resuming AEDs. Postsurgical EEGs indicated that ictal spikes in the right frontal and temporal regions reduced, while those in the left hemisphere became prominent

Radiation dose reduction for patients with extranodal NK/T-cell lymphoma with complete response after initial induction chemotherapy

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Wang L

2016-09-01

Full Text Available Liang Wang,1,2,* Xi-wen Bi,1,3,* Zhong-jun Xia,1,2 Hui-qiang Huang,1,3 Wen-qi Jiang,1,3 Yu-jing Zhang1,4 1State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 2Department of Hematologic Oncology, 3Department of Medical Oncology, 4Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China *These authors contributed equally to this work Abstract: Previous studies have found that radiotherapy (RT dose less than 50 Gy resulted in inferior outcomes for early stage extranodal NK/T-cell lymphoma (ENKTL. Nowadays, induction chemotherapy (CT followed by RT consolidation is often used. For patients who get complete response (CR after CT, whether RT dose can be safely reduced or not remains unknown. This retrospective study compared the survival outcomes between patients who received higher dose (>50 Gy and lower dose (≤50 Gy RT after CR was attained by CT. One hundred and forty four patients of early stage ENKTL got CR after induction CT and received RT consolidation. Thirty-one patients received lower dose RT (median 46 Gy, range, 36–50 Gy, and 113 patients received higher dose RT (median 56 Gy, range, 52–66 Gy. In univariate survival analysis, age >60, local tumor invasion, and non-asparaginase-based CT were associated with inferior progression-free survival (PFS and overall survival (OS. However, there were no differences in PFS and OS between patients treated with higher and lower dose RT, which was confirmed in the multivariate survival analysis. Furthermore, reduced dose RT did not affect local control rate. Most common RT-related side effects were grade 1/2 mucositis and dermatitis, and the incidence rate of grade 3 mucositis or dermatitis was lower in patients treated with reduced dose RT (9.7% vs 15.0% for mucositis, and 6.5% vs 17.7% for dermatitis. In conclusion, this study found that RT dose could be safely reduced without

Capsaicin-loaded nanolipoidal carriers for topical application: design, characterization, and in vitro/in vivo evaluation

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Wang XR

2017-05-01

Full Text Available Xia-Rong Wang,1 Si-Qian Gao,1 Xiao-Qian Niu,1 Long-Jian Li,2 Xiao-Ying Ying,1 Zhong-Jie Hu,2 Jian-Qing Gao1,3 1Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 2Zhejiang Provincial Corps Hospital of Chinese People’s Armed Police Forces, Jiaxing, Zhejiang, 3Jiangsu Engineering Research Center for New-Type External and Transdermal Preparations, Jiangsu, People’s Republic of China Abstract: Capsaicin has been used in clinical applications for the treatment of pain disorders and inflammatory diseases. Given the strong pungency and high oil/water partition coefficient of capsaicin, capsaicin-loaded nanolipoidal carriers (NLCs were designed to increase permeation and achieve the analgesic, anti-inflammatory effect with lower skin irritation. Capsaicin-loaded NLCs were prepared and later optimized by the Box–Behnken design. The physicochemical characterizations, morphology, and encapsulation of the capsaicin-loaded NLCs were subsequently confirmed. Capsaicin-loaded NLCs and capsaicin-loaded NLCs gel exhibited sustained release and no cytotoxicity properties. Also, they could significantly enhance the penetration amount, permeation flux, and skin retention amounts of capsaicin due to the application of NLCs. To study the topical permeation mechanism of capsaicin, 3,3'-dioctadecyloxacarbocyanine perchlorate (Dio was used as a fluorescent dye. Dio-loaded NLCs and Dio-loaded NLCs gel could effectively deliver Dio up to a skin depth of 260 and 210 µm, respectively, primarily through the appendage route on the basis of version skin sections compared with Dio solution, which only delivered Dio up to 150 µm. In vivo therapeutic experiments demonstrated that capsaicin-loaded NLCs and capsaicin-loaded NLCs gel could improve the pain threshold in a dose-dependent manner and inhibit inflammation, primarily by reducing the prostaglandin E2 levels in the tissue compared with capsaicin cream and capsaicin solution

Cellular uptake mechanism and comparative evaluation of antineoplastic effects of paclitaxel–cholesterol lipid emulsion on triple-negative and non-triple-negative breast cancer cell lines

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Ye J

2016-08-01

Full Text Available Jun Ye,1,2 Xuejun Xia,1,2 Wujun Dong,1,2 Huazhen Hao,1,2 Luhua Meng,1,2 Yanfang Yang,1,2 Renyun Wang,1,2 Yuanfeng Lyu,3 Yuling Liu1,2 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, 2Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 3School of Pharmacy, China Pharmaceutical University, Nanjing, People’s Republic of China Abstract: There is no effective clinical therapy for triple-negative breast cancers (TNBCs, which have high low-density lipoprotein (LDL requirements and express relatively high levels of LDL receptors (LDLRs on their membranes. In our previous study, a novel lipid emulsion based on a paclitaxel–cholesterol complex (PTX-CH Emul was developed, which exhibited improved safety and efficacy for the treatment of TNBC. To date, however, the cellular uptake mechanism and intracellular trafficking of PTX-CH Emul have not been investigated. In order to offer powerful proof for the therapeutic effects of PTX-CH Emul, we systematically studied the cellular uptake mechanism and intracellular trafficking of PTX-CH Emul and made a comparative evaluation of antineoplastic effects on TNBC (MDA-MB-231 and non-TNBC (MCF7 cell lines through in vitro and in vivo experiments. The in vitro antineoplastic effects and in vivo tumor-targeting efficiency of PTX-CH Emul were significantly more enhanced in MDA-MB-231-based models than those in MCF7-based models, which was associated with the more abundant expression profile of LDLR in MDA-MB-231 cells. The results of the cellular uptake mechanism indicated that PTX-CH Emul was internalized into breast cancer cells through the LDLR-mediated internalization pathway via clathrin-coated pits, localized in lysosomes, and then released into the cytoplasm, which was consistent with the internalization pathway and intracellular trafficking of native

Effect of micro-nano-hybrid structured hydroxyapatite bioceramics on osteogenic and cementogenic differentiation of human periodontal ligament stem cell via Wnt signaling pathway

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Mao LX

2015-11-01

Full Text Available Lixia Mao,1,* Jiaqiang Liu,1,* Jinglei Zhao,1 Jiang Chang,2 Lunguo Xia,1 Lingyong Jiang,1 Xiuhui Wang,2 Kaili Lin,2,3 Bing Fang11Center of Craniofacial Orthodontics, Department of Oral and Cranio-maxillofacial Science, Top Priority Clinical Medical Center of Shanghai Municipal Commission of Health and Family Planning, Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai Jiao Tong University, 2State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 3Shanghai Engineering Research Center of Tooth Restoration and Regeneration, School of Stomatology, Tongji University, Shanghai, People’s Republic of China*These authors contributed equally to this workAbstract: The surface structure of bioceramic scaffolds is crucial for its bioactivity and osteoinductive ability, and in recent years, human periodontal ligament stem cells have been certified to possess high osteogenic and cementogenic differential ability. In the present study, hydroxyapatite (HA bioceramics with micro-nano-hybrid surface (mnHA [the hybrid of nanorods and microrods] were fabricated via hydrothermal reaction of the α-tricalcium phosphate granules as precursors in aqueous solution, and the effects of mnHA on the attachment, proliferation, osteogenic and cementogenic differentiations of human periodontal ligament stem cells as well as the related mechanisms were systematically investigated. The results showed that mnHA bioceramics could promote cell adhesion, proliferation, alkaline phosphatase (ALP activity, and expression of osteogenic/cementogenic-related markers including runt-related transcription factor 2 (Runx2, ALP, osteocalcin (OCN, cementum attachment protein (CAP, and cementum protein (CEMP as compared to the HA bioceramics with flat and dense surface. Moreover, mnHA bioceramics stimulated gene expression of low-density lipoprotein receptor

Copper nanoparticle-induced ovarian injury, follicular atresia, apoptosis, and gene expression alterations in female rats

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Yang J

2017-08-01

Full Text Available Jing Yang,1,* Shifu Hu,1,* Meng Rao,1 Lixia Hu,2 Hui Lei,1 Yanqing Wu,1 Yingying Wang,1 Dandan Ke,1 Wei Xia,1,3 Chang-hong Zhu1,3 1Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 2Department of Histology and Embryology, Preclinical Medicine College, Xinxiang Medical University, Henan Province, Xinxiang, 3Reproductive Medicine Center, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China *These authors contributed equally to this work Abstract: Numerous studies have reported the accumulation of copper nanoparticles (Cu NPs in organs and the corresponding damage, although whether Cu NPs can be translocated to the ovaries and their ovarian toxicity are still unknown. In this study, three groups of female rats were injected with 3.12, 6.25, or 12.5 mg/kg Cu NPs for 14 consecutive days. The pathological changes, hormone levels, apoptosis and apoptotic proteins, oxidative stress, and gene expression characteristics in the ovaries were then investigated. The results demonstrated that the Cu NPs exhibited obvious accumulation in the rat ovaries, leading to ovarian injury, an imbalance of sex hormones, and ovarian cell apoptosis. Cu NP exposure activated caspase 3, caspase 8, caspase 9, and tBid, decreased the protein levels of Bcl-2, increased the expression levels of the proteins Bax and cytochrome c, and promoted malondialdehyde (MDA accumulation and superoxide dismutase (SOD reduction. Furthermore, gene microarray analysis showed that Cu NPs (12.5 mg/kg/d caused 321 differentially expressed genes. Of these, 180 and 141 genes were upregulated and downregulated, respectively. Hsd17b1, Hsd3b1, Hsd3b6, and Hsd3b were involved in steroid and hormone metabolism, whereas Mt3 and Cebpb were associated with apoptosis. Overall, these findings provide strong evidence that Cu NPs trigger both intrinsic and extrinsic

Preparation and characterization of monomethoxy poly(ethylene glycol-poly(ε-caprolactone micelles for the solubilization and in vivo delivery of luteolin

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Qiu JF

2013-08-01

Full Text Available Jin-Feng Qiu,1 Xiang Gao,1,2 Bi-Lan Wang,1 Xia-Wei Wei,1 Ma-Ling Gou,1 Ke Men,1 Xing-Yu Liu,1 Gang Guo,1 Zhi-Yong Qian,1 Mei-Juan Huang1 1Department of Thoracic Oncology, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital and Medical School, Sichuan University, Chengdu, People’s Republic of China; 2Medical School and Department of Pathophysiology, College of Preclinical and Forensic Medical Sciences, Sichuan University, Chengdu, People’s Republic of China Abstract: Luteolin (Lu is one of the flavonoids with anticancer activity, but its poor water solubility limits its use clinically. In this work, we used monomethoxy poly(ethylene glycol-poly(ε-caprolactone (MPEG-PCL micelles to encapsulate Lu by a self-assembly method, creating a water-soluble Lu/MPEG-PCL micelle. These micelles had a mean particle size of 38.6 ± 0.6 nm (polydispersity index = 0.16 ± 0.02, encapsulation efficiency of 98.32% ± 1.12%, and drug loading of 3.93% ± 0.25%. Lu/MPEG-PCL micelles could slowly release Lu in vitro. Encapsulation of Lu in MPEG-PCL micelles improved the half-life (t½; 152.25 ± 49.92 versus [vs] 7.16 ± 1.23 minutes, P = 0.007, area under the curve (0–t (2914.05 ± 445.17 vs 502.65 ± 140.12 mg/L/minute, P = 0.001, area under the curve (0–∞ (2989.03 ± 433.22 vs 503.81 ± 141.41 mg/L/minute, P = 0.001, and peak concentration (92.70 ± 11.61 vs 38.98 ± 7.73 mg/L, P = 0.003 of Lu when the drug was intravenously administered at a dose of 30 mg/kg in rats. Also, Lu/MPEG-PCL micelles maintained the cytotoxicity of Lu on 4T1 breast cancer cells (IC50 = 6.4 ± 2.30 µg/mL and C-26 colon carcinoma cells (IC50 = 12.62 ± 2.17 µg/mL in vitro. These data suggested that encapsulation of Lu into MPEG-PCL micelles created an aqueous formulation of Lu with potential anticancer effect. Keywords: luteolin, micelle, MPEG-PCL, cancer therapy

Folate-modified lipid–polymer hybrid nanoparticles for targeted paclitaxel delivery

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Zhang L

2015-03-01

Full Text Available Linhua Zhang,1 Dunwan Zhu,1 Xia Dong,1 Hongfan Sun,1 Cunxian Song,1 Chun Wang,2 Deling Kong1 1Tianjin Key Laboratory of Biomaterials, Institute of Biomedical Engineering, Peking Union Medical College and Chinese Academy of Medical Sciences, Tianjin, People’s Republic of China; 2Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA Abstract: The purpose of this study was to develop a novel lipid–polymer hybrid drug carrier comprised of folate (FA modified lipid-shell and polymer-core nanoparticles (FLPNPs for sustained, controlled, and targeted delivery of paclitaxel (PTX. The core-shell NPs consist of 1 a poly(ε-caprolactone hydrophobic core based on self-assembly of poly(ε-caprolactone–poly(ethylene glycol–poly(ε-caprolactone (PCL-PEG-PCL amphiphilic copolymers, 2 a lipid monolayer formed with 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy (polyethylene glycol-2000] (DSPE-PEG2000, 3 a targeting ligand (FA on the surface, and were prepared using a thin-film hydration and ultrasonic dispersion method. Transmission electron microscopy and dynamic light scattering analysis confirmed the coating of the lipid monolayer on the hydrophobic polymer core. Physicochemical characterizations of PTX-loaded FLPNPs, such as particle size and size distribution, zeta potential, morphology, drug loading content, encapsulation efficiency, and in vitro drug release, were also evaluated. Fluorescent microscopy proved the internalization efficiency and targeting ability of the folate conjugated on the lipid monolayer for the EMT6 cancer cells which overexpress folate receptor. In vitro cytotoxicity assay demonstrated that the cytotoxic effect of PTX-loaded FLPNPs was lower than that of Taxol®, but higher than that of PTX-loaded LPNPs (without folate conjugation. In EMT6 breast tumor model, intratumoral administration of PTX-loaded FLPNPs showed similar antitumor efficacy but low toxicity compared to Taxol®. More

A High Performance Frequency Standard and Distribution System for Cassini Ka-Band Experiment

Science.gov (United States)

2005-08-01

Orthogonal Polarization In Anisotropic Dielectric Resonators”, Proceedings of the 2002 IEEE International Frequency Control Symposium , pp. 553-558...2002. [9] G. J. Dick, Rabi T. Wang, Robert Tjoelker, “Design and Progress Report for Compact Cryocooled Sapphire Oscillator "VCSO"”, Proc. 2005 Joint...IEEE FCS/ PTTI. [10] R. Basu, G. J. Dick, Rabi T. Wang,” Novel Design of an All- Cryogenic RF Pound Circuit “,Proc. 2005 Joint IEEE FCS/ PTTI

Hydrothermal growth of ZnO nanoflowers and their photocatalyst ...

Indian Academy of Sciences (India)

JINCHENG FAN1,∗, TENGFEI LI1 and HANG HENG2,3. 1School of Materials ... In this paper, the fabrication of ZnO nanoflowers on Si substrate by the ..... [21] Bae J, Han J B, Zhang X-M, Wei M, Duan X, Zhang Y and. Wang Z L 2009 J. ... 142 570. [31] Sun Y J, Wang L, Yu X G and Chen K Z 2012 CrystEngComm. 14 3199.

KDM2B overexpression correlates with poor prognosis and regulates glioma cell growth

OpenAIRE

Wang, Yiwei; Zang, Jin; Zhang, Dongyong; Sun, Zhenxiang; Qiu, Bo; Wang, Xiaojie

2018-01-01

Yiwei Wang,1 Jin Zang,1 Dongyong Zhang,2 Zhenxiang Sun,1 Bo Qiu,2 Xiaojie Wang1 1Department of Human Anatomy, Shenyang Medical College, Huanggu District, Shenyang City, 2Department of Neurosurgery, First Affiliated Hospital of China Medical University, Heping District, Shenyang City, Liaoning Province, ChinaBackground: Gliomas are one of the most lethal cancers in the human central nervous system. Despite clinical treatment advancements, the prognosis of patients with glioma remains ...

Targeting histone abnormality in triple negative breast cancer

Science.gov (United States)

2017-08-01

mass spectrometry analysis. Briefly, we used the biotinylated primers to prepare longer double stranded biotinylated HDAC5 promoter probes...streptavidin-agarose bead suspension was added to a mixture of 400 µg of nuclear extract proteins and 4 µg of double- strand biotinylated oligonucleotides in...20 Wu Y, Wang Y, Yang XH, Kang T, Zhao Y, Wang C et al. The deubiquitinase USP28 stabilizes LSD1 and confers stem -cell-like traits to breast cancer

Migration of the Three-dimensional Wind Field (3DWF) Model from Linux to Windows and Mobile Platforms

Science.gov (United States)

2017-11-01

Results in netCDF 11 4.3 Morphological Data Generation 16 5. 3DWF on Mobile Platforms 17 5.1 3DWF on Windows Mobile Devices 18 5.2 3DWF Migration to...Windows and Mobile Platforms by Giap Huynh and Yansen Wang Approved for public release; distribution is unlimited. NOTICES...Migration of the Three-dimensional Wind Field (3DWF) Model from Linux to Windows and Mobile Platforms by Giap Huynh and Yansen Wang

Magnetic resonance-guided regional gene delivery strategy using a tumor stroma-permeable nanocarrier for pancreatic cancer

OpenAIRE

Wang, Xiaolin; Wang,Qingbing; Li,Jianfeng; An,Sai; Chen,Yi; Jiang,Chen

2015-01-01

Qingbing Wang,1,2 Jianfeng Li,3 Sai An,3 Yi Chen,1 Chen Jiang,3 Xiaolin Wang1,2 1Department of Interventional Radiology, Zhongshan Hospital, Fudan University, 2Shanghai Institute of Medical Imaging, 3Key Laboratory of Smart Drug Delivery, Ministry of Education, Department of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, People’s Republic of China Background: Gene therapy is a very promising technology for treatment of pancreatic ductal adenocarci...

Piezoelectric Nanogenerators for Self-Powered Nanosystems and Nanosensors

Science.gov (United States)

2013-05-15

researchers 1. Sangmin Lee, Sung-Hwan Bae, Long Lin, Seunghyun Ahn, Chan Park, Seung Nam Cha, Young Jun Park, Hyuk Chang, Sang-Woo Kim and...Sohn, Seung Nam Cha, Dukhyun Choi * Zhong Lin Wang * Sang-Woo Kim * “ P-Type Polymer–Hybridized High-Performance Piezoelectric Nanogenerators”, Nano...Yoon Lee, † Sang-Woo Kim , *,$ Jae-Young Choi, *,† Jong Min Kim , † and Zhong Lin Wang *, “Flexible Hybrid Multi-Type Energy Scavenger”, Energy

Metallic Material Image Segmentation by using 3D Grain Structure Consistency and Intra/Inter-Grain Model Information

Science.gov (United States)

2015-01-05

Based on these research results, we built an interactive interface as a web application using the Django [9] web framework for the backend , and a...started from 2014) ∗ Partially supported by this AFOSR grant. Publications: 1. R. Meng, S. Nelakuditi, S. Wang, R. Choudhury. OmniView: A Mobile ...11. S. Singh, R. Meng, S. Nelakuditi, Y. Tong, S. Wang. SideEye: Mobile Assistant for Blind Spot Monitoring, International Conference on Computing

A Partnership Training Program: Studying Targeted Drug Delivery Using Nanoparticles in Breast Cancer Diagnosis and Therapy

Science.gov (United States)

2013-10-01

Cancer Res, 6, 3056 (2000). 33. Dijkgraaf I, Beer AJ, Wester HJ, Front Biosci, 14, 887 (2009). 34. Lim EH, Danthi N, Bednarski M, Li KC , Nanomedicine, 1...Biol 2007;34:229-32. 34. Wang HH, Wang YX, Leung KC , Au DW, Xuan S, Chak CP, Lee SK, Sheng H, Zhang G, Qin L, Griffith JF, Ahuja AT. Durable...arylamide) (MBA), 3-(trimethoxysilyl) propylmethacrylate (MPS), tetraethoxysilane ( TEOS ), 3-(4,5)- dimethylthiahiazo(-z-yl)-3,5

Cobertura do solo e estoque de nutrientes de duas leguminosas perenes, considerando espaçamentos e densidades de plantio Soil cover and nutrient accumulation of two perennial legumes as functions of spacing and planting densities

Directory of Open Access Journals (Sweden)

A. Perin

2004-02-01

Full Text Available O estabelecimento de leguminosas herbáceas perenes nos sistemas de produção constitui ainda um desafio, principalmente por apresentarem crescimento inicial lento. Para viabilizar sua implantação, este trabalho objetivou determinar as taxas de cobertura do solo, produção de matéria seca, teores e acumulação de N, P e K das leguminosas herbáceas perenes galáxia (Galactia striata e cudzu tropical (Pueraria phaseoloides, considerando espaçamentos e densidades de plantio. O experimento, instalado em dezembro/98 na Embrapa Agrobiologia, Seropédica (RJ, constou do delineamento em blocos ao acaso, em arranjo fatorial 2 x 2 x 4, com quatro repetições. Os tratamentos constaram das espécies galáxia e cudzu tropical, plantadas em dois espaçamentos entre sulcos de plantio (25 e 50 cm e quatro densidades de plantas (5, 10, 15 e 20 plantas m-1. A densidade adequada para a rápida cobertura do solo para cudzu tropical e galáxia foi de 10 plantas m-1, no espaçamento de 25 cm entre os sulcos de plantio. A maior produção de matéria seca e acumulação de N, P e K na parte aérea das plantas foram evidenciadas apenas no primeiro corte, sendo os maiores valores obtidos no espaçamento de 25 cm e na densidade de 10 plantas m-1. O espaçamento de 25 cm com 10 plantas m-1 foi a combinação mais adequada para a plena formação da cobertura viva do solo com cudzu tropical e galáxia.The establishment of herbaceous perennial leguminous in production systems is still a challenge, mainly because of the slow initial growth. Evaluations of the soil cover ratio, dry matter production, contents and accumulations of nitrogen, phosphorus, and potassium of the herbaceous perennial Galactia striata and Pueraria phaseoloides, sown in different densities and row spacing, aimed at making their establishments feasible. The experiment was conducted in December/98 at Embrapa Agrobiologia, Seropédica (RJ, in a completely randomized block design, as a factorial

Organic photovoltaics

Science.gov (United States)

Demming, Anna; Krebs, Frederik C.; Chen, Hongzheng

2013-12-01

X, Jin Z, Li K, Wang S, Wang H and Ma W 2013 Low-temperature, solution-processed alumina for organic solar cells Nanotechnology 24 484010 [12] Chen F, Chen Q, Mao L, Wang Y, Huang X, Lu W, Wang B and Chen L 2013 Tuning ITO work function with solution-processed alkali carbonate interfacial layers for high-efficiency inverted organic photovoltaic cells Nanotechnology 24 484011 [13] Wu Z, Song T, Xia Z, Wei H and Sun B 2013 Enhanced performance of polymer solar cell with ZnO nanoparticle electron transporting layer passivated by in situ cross-linked three-dimensional polymer network Nanotechnology 24 484012 [14] Urbina A, Park J-S, Lee J-M, Kim S-O and Kim J-S 2013 Work function engineering of ZnO electrodes by using p-type and n-type doped carbon nanotubes Nanotechnology 24 484013 [15] van de Wiel H J et al 2013 R2R embedded conductive structures integrated into OPV devices Nanotechnology 24 484014

Rapid Translation of a Novel and Potent Vaccine in HER2+ Metastatic Breast Cancer Patients

Science.gov (United States)

2013-10-01

Xia3, Neil Spector2,3, Larry S Barak4, Timothy M Clay5, Takuya Osada2, Erika Hamilton6, Kimberly Blackwell6, Amy C Hobeika2, Michael A Morse2,3, H Kim...Zhang L, Boehm MF, Fritz LC, Burrows FJ: A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors. Nature 2003, 425:407...410. 13. Zhang H, Burrows F: Targeting multiple signal transduction pathways through inhibition of Hsp90. J Mol Med (Berl) 2004, 82:488-499. 14. Basso

Magnetotransport in Two Dimensional Electron Systems Under Microwave Excitation and in Highly Oriented Pyrolytic Graphite

Science.gov (United States)

2012-01-01

Phys. Rev. Lett. 82, 2147 (1999). [89] Y. Zhang, Y. Tan, H. L. Stormer and P. Kim, Nature 438, 10 (2005). [90] J. W. McClure, Phys. Rev. 108, 612 (1957...Phys. 2, 595 (2006). [97] H. L. Stormer , J. P. Eisenstein, A. C. Gossard, W. Wiegmann, and K. Baldwin, Phys. Rev. Lett. 56, 85 (1985). [98] B. A...Sadowski, J. M. Schneider, and M. Potemski, J. Phys.: Cond. Matter 20, 454223 (2008). [108] W. Pan, J. S. Xia, H. L. Stormer , D. C. Tsui, C. L

Investigating Metabolic Control of Persister Formation in Biofilms

Science.gov (United States)

2013-10-01

Beer , K., McKay, G., Siehnel, R., Schafhauser, J., Wang, Y., et al. (2011). Active starva- tion responses mediate antibiotic tolerance in biofilms and...ATP concentration in Escherichia coli fermentations . Biotechnology and bioengineering 52, 364-372. Lemke, J.J., Sanchez-Vazquez, P., Burgos, H.L...1082– 1093. 33. Nguyen D, Joshi-Datar A, Lepine F, Bauerle E, Olakanmi O, Beer K, McKay G, Siehnel R, Schafhauser J, Wang Y, Britigan BE, Singh PK. 2011

Intranasal delivery of Huperzine A to the brain using lactoferrin-conjugated N-trimethylated chitosan surface-modified PLGA nanoparticles for treatment of Alzheimer’s disease

OpenAIRE

Meng,Qingqing; Wang,Aiping; Hua,Hongchen; Jiang,Ying; Wang,Yiyun; Mu,Hongjie; Wu,Zimei; Sun,Kaoxiang

2018-01-01

Qingqing Meng,1,* Aiping Wang,1,2,* Hongchen Hua,1 Ying Jiang,1 Yiyun Wang,1 Hongjie Mu,1 Zimei Wu,1 Kaoxiang Sun1 1School of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, People’s Republic of China; 2State Key Laboratory of Long-Acting and Targeting Drug Delivery System, Shandong Luye Pharmaceutical Co., Ltd, Yantai, People’s Republic of China *These authors contribute...

CXCL14 Blockade of CXCL12/CXCR4 Signaling in Prostate Cancer Bone Metastasis

Science.gov (United States)

2017-10-01

10.1158/0008-5472.CAN-04-3785. 55. Jung Y, Kim JK, Shiozawa Y, Wang J, Mishra A, Joseph J, Berry JE, McGee S, Lee E, Sun H, Wang J, Jin T, Zhang H...and unfortunate complication of advanced prostate cancer resulting in significant pain and fractures . The most devastating consequence, however, is...treatments. These data suggest a mechanism of increased migration and invasion may be associated with expression of EMT genes. Regulation of Kinase

Sustained release of bactericidal concentrations of penicillin in the pleural space via an antibiotic-eluting pigtail catheter coated with electrospun nanofibers: results from in vivo and in vitro studies

OpenAIRE

Chao, Yin-Kai; Lee, Cheng-Hung; Liu, Kuo-Sheng; Wang, Yi-Chuan; Wang, Chih-Wei; Liu, Shih-Jung

2015-01-01

Yin-Kai Chao,1 Cheng-Hung Lee,2 Kuo-Sheng Liu,1 Yi-Chuan Wang,3 Chih-Wei Wang,4 Shih-Jung Liu3 1Department of Thoracic and Cardiovascular Surgery, Chang Gung Memorial Hospital-Linkou, College of Medicine, Chang Gung University, Taoyuan, Taiwan; 2Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital-Linkou, College of Medicine, Chang Gung University, Taoyuan, Taiwan; 3Department of Mechanical Engineering, Chang Gung University, Taoyuan, Taiwan; 4Department of P...

Identification and Characterization of Distinct Apoptotic Pathways in Cancer Cells Activated in Response to Treatment with Different Anti-Cancer Agents

Science.gov (United States)

2000-08-01

caspases precursors in different cell type induce apoptosis (Miura et al. 1993; Fernandes- 3 Alnemri et al. 1994; Kumar et al. 1994; Wang et al. 1994; Boldin ...association of ribosomes with mRNA. The lysates were sedimented through a linear sucrose gradient and fractions were collected. RNA was extracted from...precursors in different cell type induces apoptosis (Miura et al. 1993; Fernandes- Alnemri et al. 1994; Kumar et al. 1994; Wang et al. 1994; Boldin et al

Myometrial invasion and overall staging of endometrial carcinoma: assessment using fusion of T2-weighted magnetic resonance imaging and diffusion-weighted magnetic resonance imaging

OpenAIRE

Guo, Yu; Wang, Ping; Wang, Penghui; Gao, Wei; Li, Fenge; Yang, Xueling; Ni, Hongyan; Shen, Wen; Guo, Zhi

2017-01-01

Yu Guo,1,2 Ping Wang,2 Penghui Wang,2 Wei Gao,1 Fenge Li,3 Xueling Yang,1 Hongyan Ni,2 Wen Shen,2 Zhi Guo1 1Department of Interventional Therapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin, 2Department of Radiology, Tianjin First Center Hospital, The First Central Clinical College of Tianjin Medical University,...

Design, synthesis, and evaluation of VEGFR-targeted macromolecular MRI contrast agent based on biotin?avidin-specific binding

OpenAIRE

Liu, Yongjun; Wu, Xiaoyun; Sun, Xiaohe; Wang, Dan; Zhong, Ying; Jiang, Dandan; Wang, Tianqi; Yu, Dexin; Zhang, Na

2017-01-01

Yongjun Liu,1 Xiaoyun Wu,1 Xiaohe Sun,1 Dan Wang,1 Ying Zhong,1 Dandan Jiang,1 Tianqi Wang,1 Dexin Yu,2 Na Zhang1 1School of Pharmaceutical Science, Shandong University, 2Department of Radiology Medicine, Qilu Hospital, Jinan, People’s Republic of China Abstract: Developing magnetic resonance imaging (MRI) contrast agents with high relaxivity and specificity was essential to increase MRI diagnostic sensitivity and accuracy. In this study, the MRI contrast agent, vascular endotheli...

Spatially correlated heterogeneous aspirations to enhance network reciprocity

Science.gov (United States)

Tanimoto, Jun; Nakata, Makoto; Hagishima, Aya; Ikegaya, Naoki

2012-02-01

Perc & Wang demonstrated that aspiring to be the fittest under conditions of pairwise strategy updating enhances network reciprocity in structured populations playing 2×2 Prisoner's Dilemma games (Z. Wang, M. Perc, Aspiring to the fittest and promoted of cooperation in the Prisoner's Dilemma game, Physical Review E 82 (2010) 021115; M. Perc, Z. Wang, Heterogeneous aspiration promotes cooperation in the Prisoner's Dilemma game, PLOS one 5 (12) (2010) e15117). Through numerical simulations, this paper shows that network reciprocity is even greater if heterogeneous aspirations are imposed. We also suggest why heterogeneous aspiration fosters network reciprocity. It distributes strategy updating speed among agents in a manner that fortifies the initially allocated cooperators' clusters against invasion. This finding prompted us to further enhance the usual heterogeneous aspiration cases for heterogeneous network topologies. We find that a negative correlation between degree and aspiration level does extend cooperation among heterogeneously structured agents.

Breaking a chaos-based secure communication scheme designed by an improved modulation method

Energy Technology Data Exchange (ETDEWEB)

Li Shujun [Department of Electronic Engineering, City University of Hong Kong, Kowloon, Hong Kong (China)]. E-mail: hooklee@mail.com; Alvarez, Gonzalo [Instituto de Fisica Aplicada, Consejo Superior de Investigaciones Cientificas, Serrano 144-28006 Madrid (Spain); Chen Guanrong [Department of Electronic Engineering, City University of Hong Kong, Kowloon, Hong Kong (China)

2005-07-01

Recently Bu and Wang [Bu S, Wang B-H. Chaos, Solitons and Fractals 2004;19(4):919-24] proposed a simple modulation method aiming to improve the security of chaos-based secure communications against return-map-based attacks. Soon this modulation method was independently cryptanalyzed by Chee et al. [Chee CY, Xu D, Bishop SR. Chaos, Solitons and Fractals 2004;21(5):1129-34], Wu et al. [Wu X, Hu H, Zhang B. Chaos, Solitons and Fractals 2004;22(2):367-73], and Alvarez et al. [Alvarez G, Montoya F, Romera M, Pastor G. Chaos, Solitons and Fractals, in press, arXiv:nlin/0406065] via different attacks. As an enhancement to the Bu-Wang method, an improving scheme was suggested by Wu et al. by removing the relationship between the modulating function and the zero-points. The present paper points out that the improved scheme proposed by Wu et al. is still insecure against a new attack. Compared with the existing attacks, the proposed attack is more powerful and can also break the original Bu-Wang scheme. Furthermore, it is pointed out that the security of the modulation-based schemes proposed by Wu et al. is not so satisfactory from a pure cryptographical point of view. The synchronization performance of this class of modulation-based schemes is also discussed.

Breaking a chaos-based secure communication scheme designed by an improved modulation method

International Nuclear Information System (INIS)

Li Shujun; Alvarez, Gonzalo; Chen Guanrong

2005-01-01

Recently Bu and Wang [Bu S, Wang B-H. Chaos, Solitons and Fractals 2004;19(4):919-24] proposed a simple modulation method aiming to improve the security of chaos-based secure communications against return-map-based attacks. Soon this modulation method was independently cryptanalyzed by Chee et al. [Chee CY, Xu D, Bishop SR. Chaos, Solitons and Fractals 2004;21(5):1129-34], Wu et al. [Wu X, Hu H, Zhang B. Chaos, Solitons and Fractals 2004;22(2):367-73], and Alvarez et al. [Alvarez G, Montoya F, Romera M, Pastor G. Chaos, Solitons and Fractals, in press, arXiv:nlin/0406065] via different attacks. As an enhancement to the Bu-Wang method, an improving scheme was suggested by Wu et al. by removing the relationship between the modulating function and the zero-points. The present paper points out that the improved scheme proposed by Wu et al. is still insecure against a new attack. Compared with the existing attacks, the proposed attack is more powerful and can also break the original Bu-Wang scheme. Furthermore, it is pointed out that the security of the modulation-based schemes proposed by Wu et al. is not so satisfactory from a pure cryptographical point of view. The synchronization performance of this class of modulation-based schemes is also discussed

Evidence of topological insulator state in the semimetal LaBi

Science.gov (United States)

Lou, R.; Fu, B.-B.; Xu, Q. N.; Guo, P.-J.; Kong, L.-Y.; Zeng, L.-K.; Ma, J.-Z.; Richard, P.; Fang, C.; Huang, Y.-B.; Sun, S.-S.; Wang, Q.; Wang, L.; Shi, Y.-G.; Lei, H. C.; Liu, K.; Weng, H. M.; Qian, T.; Ding, H.; Wang, S.-C.

2017-03-01

By employing angle-resolved photoemission spectroscopy combined with first-principles calculations, we performed a systematic investigation on the electronic structure of LaBi, which exhibits extremely large magnetoresistance (XMR), and is theoretically predicted to possess band anticrossing with nontrivial topological properties. Here, the observations of the Fermi-surface topology and band dispersions are similar to previous studies on LaSb [L.-K. Zeng, R. Lou, D.-S. Wu, Q. N. Xu, P.-J. Guo, L.-Y. Kong, Y.-G. Zhong, J.-Z. Ma, B.-B. Fu, P. Richard, P. Wang, G. T. Liu, L. Lu, Y.-B. Huang, C. Fang, S.-S. Sun, Q. Wang, L. Wang, Y.-G. Shi, H. M. Weng, H.-C. Lei, K. Liu, S.-C. Wang, T. Qian, J.-L. Luo, and H. Ding, Phys. Rev. Lett. 117, 127204 (2016), 10.1103/PhysRevLett.117.127204], a topologically trivial XMR semimetal, except the existence of a band inversion along the Γ -X direction, with one massless and one gapped Dirac-like surface state at the X and Γ points, respectively. The odd number of massless Dirac cones suggests that LaBi is analogous to the time-reversal Z2 nontrivial topological insulator. These findings open up a new series for exploring novel topological states and investigating their evolution from the perspective of topological phase transition within the family of rare-earth monopnictides.

Reatividade vascular da artéria mamária interna: estudos farmacológicos comparativos entre artérias caninas direita e esquerda

Directory of Open Access Journals (Sweden)

EVORA Paulo Roberto B.

1999-01-01

Full Text Available Para estudos comparativos da reatividade vascular entre artéria mamária interna (AMI canina direita e esquerda, realizaram-se experimentos "in vitro" utilizando-se banhos orgânicos ("organ chambers" e ensaios biológicos: 1 os produtos plaquetários ADP e 5-HT induziram, respectivamente, vasodilatação dependente e independente do endotélio; 2 os autacóides, bradicinina e histamina, também induziram vasodilatação, respectivamente, dependente e independente do endotélio; 3 o A23187, vasodilatador independente de receptor, induziu relaxamentos dependentes do endotélio; 4 dopamina, dobutamina, papaverina e a poli-L-arginina induziram vasodilatações independentes do endotélio; 5 a NOR induziu intensa vasoconstrição comparável à causada pelo KCI e pela endotelina; 6 em 83% de 24 ensaios, a liberação basal de NO foi maior na AMI esquerda, em comparação com a AMI direita; 7 ensaios biológicos de AMIs demonstraram a importância da PGI2 nas condições de hipóxia, uma vez que a indometacina aboliu vasodilatação adicional em resposta à hipóxia em condições de vasodilatação induzida pela liberação basal de NO; 8 não ocorreram diferenças significantes de resposta, comparando-se estudos realizados em AMIs direita e esquerda.

Taxonomic notes on Neoperla (Plecoptera: Perlidae) from Sichuan Province of China with the description of two new species.

Science.gov (United States)

Li, Weihai; Wang, Ying; Wang, Rongfeng

2017-01-17

Species of the perlid genus Neoperla from Sichuan Province, China are reviewed. Two new species are described, Neoperla caii Li & Wang, sp. nov. and N. emeishana Li & Wang, sp. nov. The new species are compared with related congeners. Available types of several known Neoperla species from Sichuan Province were studied and complementary descriptions or brief taxonomic comments are presented for N. bilineata Wu & Claassen, N. chui Wu & Claassen, N. microtumida Wu & Claassen, N. quadrata Wu & Claassen and N. truncata Wu.

Efficient preparation and labeling of human induced pluripotent stem cells by nanotechnology

OpenAIRE

Ruan, Jing; Shen,; Wang ,Z; Ji,; Song,; Wang,; Liu,Bao-Liang; Li,; Cui,Daxiang

2011-01-01

Jing Ruan1,*, Jie Shen2,*, Zheng Wang2, Jiajia Ji1, Hua Song1, Kan Wang1, Bin Liu1, Jinhui Li2, Daxiang Cui11Department of Bio-Nano Science and Engineering, Key Laboratory for Thin Film and Microfabrication Technology of the Ministry of Education, National Key Laboratory of Micro/Nano Fabrication Technology, Research Institute of Micro/Nano Science and Technology, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 2Shanghai Institute of Digestive Diseases, Shanghai...

Characteristics and Functionalities of Natural and Bioinspired Nanomaterials

Science.gov (United States)

2012-05-01

Phytomedicine 2002, 9, 560-565. 24. Shen, C. C.; Tsai, S. Y.; Wei, S. L.; Wang, S. T.; Shieh, B. J., et al., Flavonoids isolated from Draconis...from Panax notoginseng using human platelet extraction and HPLC -DAD-ESI-MS/MS. J. Sep. Sci. 2008, 31, 1173-1180. 35. Wang, J.; Xu, J.; Zhong, J. B...339, 131-153. 59. Xin, H. L.; Wu, Y. C.; Su, Y. H.; Sheng, J. Y.; Ling, C. Q., Novel flavonoids from the leaves of Actinidia valvata Dunn

Westward movement of eddies into the Gulf of Aden from the Arabian Sea

Digital Repository Service at National Institute of Oceanography (India)

Al Saafani, M.A.; Shenoi, S.S.C.; Shankar, D.; Aparna, M.; Kurian, J.; Durand, F.; Vinayachandran, P.N.

forced SLA response and the Rossby waves from the east, constructive/destructive interference will create a discontinuity [Wang et al., 2001] similar to that noted in Figures 5a and 5b. Wang et al. [2001] noticed a similar discontinuity in the annual... Rossby waves in the interior of the southern Indian Ocean; that discontinuity was caused by constructive/destructive interference between the locally forced response and the Rossby waves propagating from the east. [26] The high-frequency wavelets of Ekman...

Maintenance of Glucose Homeostasis Through Acetylation of the Metabolic Transcriptional Coactivator PGC1-alpha

Science.gov (United States)

2011-02-01

Salmenniemi, U., Ruotsalainen, E., Pihlajamaki, J., Vauhkonen, I., Kai - nulainen, S., Punnonen, K., Vanninen, E., and Laakso, M. (2004). Mul- tiple...cancer: a dawn for evolutionary medicine. Annu. Rev. Genet. 39, 359–407. Wang, Y.X., Zhang, C.L., Yu , R.T., Cho, H.K., Nelson, M.C., Bayuga- Ocampo...calorie diet, Nature 444 (2006) 337–342. [19] J.M. Wu, Z.R. Wang, T.C. Hsieh , J.L. Bruder, J.G. Zou, Y.Z. Huang, Mechanism of cardioprotection by

MicroRNA-200c: A Novel Way to Attack Breast Cancer Metastases by Restoring the Epithelial Phenotype

Science.gov (United States)

2012-02-01

other provision of law , no person shall be subject to any penalty for failing to comply with a collection of information if it does not display a...biallelic loss of Dicer1 promotes tumorigenesis in vivo. Cell Death Differ 17 (4):633–641 38. Law JH, Habibi G, Hu K, Masoudi H, Wang MY, Stratford AL...Reinhardt F, Benaich N, Calogrias D, Szasz AM, Wang ZC, et al. A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell

Reconciling late Quaternary transgressions in the Bohai Sea, China to the global sea level changes, and new linkage of sedimentary records to three astronomical rhythms

Science.gov (United States)

Yi, Liang

2013-04-01

Terminations. Science 326, 248-252. Ding, Z.L., Yu, Z.W., Rutter, N.W., Liu, T.S., 1994. Towards an orbital time scale for chinese loess deposits. Quaternary Science Reviews 13, 39-70. IOCAS (Institute of Oceanology, Chinese Academy of Sciences), 1985. Bohai Sea Geology. Science Press, Beijing, China. Liu, T., 2009. Loess and Arid Environment. Anhui Science & Techonology Press, Hefei, China. Wang, Y., Cheng, H., Edwards, R.L., An, Z., Wu, J., Chen, C.-C., Dorale, J.A., 2001. A High-Resolution Absolute-Dated Late Pleistocene Monsoon Record from Hulu Cave, China. Science 294, 2345-2348. Wang, Y., Cheng, H., Edwards, R.L., Kong, X., Shao, X., Chen, S., Wu, J., Jiang, X., Wang, X., An, Z., 2008. Millennial- and orbital-scale changes in the East Asian monsoon over the past 224,000 years. Nature 451, 1090-1093. Yi, L., Yu, H., Ortiz, J.D., Xu, X., Chen, S., Ge, J., Hao, Q., Yao, J., Shi, X., Peng, S., 2012a. Late Quaternary linkage of sedimentary records to three astronomical rhythms and the Asian monsoon, inferred from a coastal borehole in the south Bohai Sea, China. Palaeogeography, Palaeoclimatology, Palaeoecology 329-310, 101-117. Yi, L., Lai, Z.P., Yu, H.J., Xu, X.Y., Su, Q., Yao, J., Wang, X.L., Shi, X., 2012b. Chronologies of sedimentary changes in the south Bohai Sea, China: Constraints from luminescence and radiocarbon dating. Boreas, doi: 10.1111/j.1502-3885.2012.00271.x. Yi, L., Yu, H.J., Ortiz, J.D., Xu, X.Y., Qiang, X.K., Huang, H.J., Shi, X., Deng, C.L., 2012c. A reconstruction of late Pleistocene relative sea level in the south Bohai Sea, China, based on sediment grain-size analysis. Sedimentary Geology 281, 88-100. Zhao, S., Yang, G., Cang, S., Zhang, H., Huang, Q., Xia, D., Wang, Y., Liu, F., Liu, C., 1978. Transgression's stratas and shoreline changes in the south coast of Bohai Bay, China. Oceanologia et Limnologia Sinica 9, 15-25.

Water use efficiency and integrated water resource management for river basin

Science.gov (United States)

Deng, Xiangzheng; Singh, R. B.; Liu, Junguo; Güneralp, Burak

Water use efficiency and management have attracted increasing attention as water has become scare to challenge the world's sustainable development. Water use efficiency is correlated to the land use and cover changes (LUCC), population distribution, industrial structure, economic development, climate changes, and environmental governance. These factors significantly alter water productivity for water balance through the changes in natural environment and socio-economic system (Wang et al., 2015b). Consequently, dynamics of water inefficiency lower the social welfare of water allocation (Wang et al., 2015b), and induce water management alternation interactively and financially (Wang et al., 2015a). This triggers on actual water price changes through both natural resource and socioeconomic system (Zhou et al., 2015). Therefore, it is very important to figure out a mechanism of water allocation in the course of LUCC (Jin et al., 2015) at a global perspective (Zhao et al., 2015), climate and economic changes of ecosystem service at various spatial and temporal scales (Li et al., 2015).

New modular relations involving cubes of the Göllnitz–Gordon ...

Indian Academy of Sciences (India)

q7)T (q3). S(q21)T (q) − q10T (q21)S(q). = f4f21 f7f12 . (1.34). 2. Proof of Theorem 1.1. The following 2-dissection formulas of f1 and 1 f1 were proved by Xia and Yao [20]: f1 = f4S(−q2) − qf4T (−q2). (2.1) and. 1 f1. = f 2. 4 f 3. 2. S(−q2) + q f 2. 4.

Microfluidics as a tool for micro-manipulation

CSIR Research Space (South Africa)

Potgieter, S

2008-10-01

Full Text Available , exists (Xia & Whitesides, 1998). PDMS (Dow Corning Sylgard 184) will be poured into the moulds and cured to create the flow channels. Channel dimensions in the order of 100 µm deep and 100 µm wide will be used initially. To visualise particle.... DUFFY, D.C., MCDONALD, J.C., SCHUELLER, O.J.A., WHITESIDES, G.M. “Rapid prototyping of microfluidic systems in poly(dimethylsiloxane)”, Analytical Chemistry, 70, pp. 4974 – 4984, 1998. LIU, L., CAO, W., WU, J., WEN, W., CHANG, D.C., SHENG, P...

A Discussion of the Origin of the Erligang Culture%二里岗文化渊源刍议

Institute of Scientific and Technical Information of China (English)

程平山

2001-01-01

This paper argues that the Erligang Culture was a mixture of the Erlitou-type Culture, the Zhanghe - type Culture and the special Erligang features. The Erliang Culture was a development of the Pre - Shang Culture and the Pre - Shang Culture and the Lower Erligang Culture represented the same Shang culture before and after the collapse of the Xia Dynasty and they had little difference in nature. It further argues that the formation of the Erligang culture began in Shangqiu district, thus Shangqiu remains and important area in exploring thePre - Shang Culture

Hernias cerebrais intracranianas

Directory of Open Access Journals (Sweden)

João Guidugli Neto

1975-12-01

Full Text Available O autor estuda as diferentes manifestações macroscópicas de deslocamento intracraniano de massa encefálica em 420 encéfalos. Em 23 destes havia lesão secundária do tronco cerebral. A hérnia temporal uni ou bilateral foi a alteração mais frequente no material, sendo a anóxia terminal provavelmente um dos fatores importantes no seu estabelecimento. Foi verificado decréscimo acentuado das lesões secundárias do tronco cerebral após os 60 anos de idade.

The CARDS array for neutron-rich decay spectroscopy at HRIBF

CERN Document Server

Batchelder, J C; Bingham, C R; Carter, H K; Cole, J D; Fong, D; Garrett, P E; Grzywacz, R; Hamilton, J H; Hartley, D J; Hwang, J K; Krolas, W; Kulp, D C; Larochelle, Y; Piechaczek, A; Ramayya, A V; Rykaczewski, K; Spejewski, E H; Stracener, D W; Tantawy, M N; Winger, J A; Wood, J; Zganjar, E F

2003-01-01

An array for decay studies of neutron-rich nuclei has been commissioned for use at the UNISOR separator at Holifield Radioactive Ion Beam Facility. This array consists of three segmented clover Ge detectors, plastic scintillators, and a high-resolution (approx 1 keV) Si conversion electron spectrometer. These detectors are mounted on a support that surrounds a moving tape collector. This system has been named clover array for radioactive decay studies. The detectors have been outfitted with digital flash ADCs (XIA DGFs) that fit the preamp signals, with built-in pileup rejection.

The CARDS array for neutron-rich decay spectroscopy at HRIBF

International Nuclear Information System (INIS)

Batchelder, J.C.; Bilheux, J.-C.; Bingham, C.R.; Carter, H.K.; Cole, J.D.; Fong, D.; Garrett, P.E.; Grzywacz, R.; Hamilton, J.H.; Hartley, D.J.; Hwang, J.K.; Krolas, W.; Kulp, D.; Larochelle, Y.; Piechaczek, A.; Ramayya, A.V.; Rykaczewski, K.P.; Spejewski, E.H.; Stracener, D.W.; Tantawy, M.N.; Winger, J.A.; Wood, J.; Zganjar, E.F.

2003-01-01

An array for decay studies of neutron-rich nuclei has been commissioned for use at the UNISOR separator at Holifield Radioactive Ion Beam Facility. This array consists of three segmented clover Ge detectors, plastic scintillators, and a high-resolution (∼1 keV) Si conversion electron spectrometer. These detectors are mounted on a support that surrounds a moving tape collector. This system has been named clover array for radioactive decay studies. The detectors have been outfitted with digital flash ADCs (XIA DGFs) that fit the preamp signals, with built-in pileup rejection

Size-controlled fabrication of zein nano/microparticles by modified anti-solvent precipitation with/without sodium caseinate

OpenAIRE

Li, Feng; Chen, Yan; Liu, Shubo; Qi, Jian; Wang, Weiying; Wang, Chenhua; Zhong, Ruiyue; Chen, Zhijun; Li, Xiaoming; Guan, Yuanzhou; Kong, Wei; Zhang, Yong

2017-01-01

Feng Li,1 Yan Chen,1,2 Shubo Liu,1 Jian Qi,1 Weiying Wang,1 Chenhua Wang,1 Ruiyue Zhong,1 Zhijun Chen,1 Xiaoming Li,1 Yuanzhou Guan,1 Wei Kong,1,2 Yong Zhang1,2 1National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, 2Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, School of Life Sciences, Jilin University, Changchun, China Abstract: Zein-based nano/microparticles have been demonstrated to be promising carr...

Evaluation of clear-sky incoming radiation estimating equations typically used in remote sensing evapotranspiration algorithms

CSIR Research Space (South Africa)

Sun, Z

2013-09-01

Full Text Available , Mekonnen Gebremichael 2,*, Qinxue Wang 1, Junming Wang 3, Ted W. Sammis 4 and Alecia Nickless 5 1 National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki 305-8506, Japan; E-Mails: sun.zhigang@nies.go.jp (Z.S.); wangqx@nies.go.jp (Q... Development Fund (E-1203) of the Ministry of the Environment, Japan. Authors thank anonymous reviewers and editors for their constructive comments. Conflicts of Interest The authors declare no conflict of interest. References 1. Ruhoff, A.L.; Paz, A...

The Role of ERG and CXCR4 in Prostate Cancer Progression

Science.gov (United States)

2013-06-01

NI, Koh -Paige AJ, Shim H, et al. (2005). Skeletal localization and neutralization of the SDF-1(CXCL12)/CXCR4 axis blocks prostate cancer metastasis...cancer metastasis and growth in osseous sites in vivo. J Bone Miner Res. 2005;20(2):318-29. 34. Ao M, Franco OE, Park D, Raman D, Williams K...Schneider A, Jung Y, Wang J, Dai J, Wang J, Cook K, Osman NI, Koh -Paige AJ, Shim H, et al: Skeletal localization and neutralization of the SDF- 1(CXCL12

Iterative methods used in overlap astrometric reduction techniques do not always converge

Science.gov (United States)

Rapaport, M.; Ducourant, C.; Colin, J.; Le Campion, J. F.

1993-04-01

In this paper we prove that the classical Gauss-Seidel type iterative methods used for the solution of the reduced normal equations occurring in overlapping reduction methods of astrometry do not always converge. We exhibit examples of divergence. We then analyze an alternative algorithm proposed by Wang (1985). We prove the consistency of this algorithm and verify that it can be convergent while the Gauss-Seidel method is divergent. We conjecture the convergence of Wang method for the solution of astrometric problems using overlap techniques.

The green computing book tackling energy efficiency at large scale

CERN Document Server

Feng, Wu-chun

2014-01-01

Low-Power, Massively Parallel, Energy-Efficient Supercomputers The Blue Gene TeamCompiler-Driven Energy Efficiency Mahmut Kandemir and Shekhar Srikantaiah An Adaptive Run-Time System for Improving Energy Efficiency Chung-Hsing Hsu, Wu-chun Feng, and Stephen W. PooleEnergy-Efficient Multithreading through Run-Time Adaptation Exploring Trade-Offs between Energy Savings and Reliability in Storage Systems Ali R. Butt, Puranjoy Bhattacharjee, Guanying Wang, and Chris GniadyCross-Layer Power Management Zhikui Wang and Parthasarathy Ranganathan Energy-Efficient Virtualized Systems Ripal Nathuji and K

Comment on 'Effects of hydrogen dilution on deposition process of nano-crystalline silicon film by SiCl4/H2 plasma'

International Nuclear Information System (INIS)

Tanarro, Isabel

2007-01-01

In a recent paper, Wang et al (2006 J. Phys. D: Appl. Phys. 39 3030) have reported the effects of hydrogen dilution ratio on the relative densities of SiCl n (n = 0-2) radicals in a SiCl 4 /H 2 plasma generated in a RF low pressure discharge. This comment argues that the radical detection method proposed and used by Wang et al is not appropriate to estimate radical concentrations and that the experimental results obtained with it consequently seem to be unreliable. (comment)

Proceedings of the Annual Meeting of the Technical Documentation Division (22nd) Held on 21-23 May, 1980 at the U.S. Naval Station, Charleston, South Carolina.

Science.gov (United States)

1980-05-01

PETER C.C. Wang Code 53 WG MR. JOHN R. HART Dept of Mathmatics and National Boeing Aerospace Company Security Affairs P.O. Box 3999, M/S 42-01 Naval...but there was major concern voiced over the current existence of two national standards on the same subject. f) Dr. Peter Wang, our Chairman of the...o- 183f - , an: oreoser new or revised regulations a. LxPansuori of too appiicbts sam: units F-,- 220 wrliz~ lesa:; zec Inc use c7 m $sliancsrs

A rare adverse reaction of sorafenib | Wang | Libyan Journal of ...

African Journals Online (AJOL)

2007-10-30

Sorafenib is a multikinase inhibitor thought to target vascular endothelial growth factor and its receptor. The European Medicines Agency (EAMA) and Food and Drug Administration (FDA) approved the use of sorafenib in late-stage hepatic cellular cancer (HCC) on October 30, 2007, and November 19, 2007, respectively.

Hiina mõistatus : Wang-Ba ja palju muudki / Erkki Bahovski

Index Scriptorium Estoniae

Bahovski, Erkki, 1970-

2008-01-01

Artikli autor annab ülevaate Euroopa Välissuhete Nõukogu tegevdirektori Mark Leonardi raamatust "What Does China Think?". Raamatu autori väide on lihtne: selleks, et aru saada maailma poliitikast, tuleb aru saada Hiinas toimuvast

Rice field for the treatment of pond aquaculture effluents | Wang ...

African Journals Online (AJOL)

We conducted an experiment to evaluate the efficiency of rice fields in treating pond aquaculture effluent and its responses to different fertilizer treatments. Four treatments was considered in the experiment: no rice planted as the control (CT); rice planted and no fertilizer input (RE); rice planted and a rate of approximately ...

Computational Thermodynamics of Materials Zi-Kui Liu and Yi Wang

Energy Technology Data Exchange (ETDEWEB)

Devanathan, Ram

2017-02-01

This authoritative volume introduces the reader to computational thermodynamics and the use of this approach to the design of material properties by tailoring the chemical composition. The text covers applications of this approach, introduces the relevant computational codes, and offers exercises at the end of each chapter. The book has nine chapters and two appendices that provide background material on computer codes. Chapter 1 covers the first and second laws of thermodynamics, introduces the spinodal as the limit of stability, and presents the Gibbs-Duhem equation. Chapter 2 focuses on the Gibbs energy function. Starting with a homogeneous system with a single phase, the authors proceed to phases with variable compositions, and polymer blends. The discussion includes the contributions of external electric and magnetic fields to the Gibbs energy. Chapter 3 deals with phase equilibria in heterogeneous systems, the Gibbs phase rule, and phase diagrams. Chapter 4 briefly covers experimental measurements of thermodynamic properties used as input for thermodynamic modeling by Calculation of Phase Diagrams (CALPHAD). Chapter 5 discusses the use of density functional theory to obtain thermochemical data and fill gaps where experimental data is missing. The reader is introduced to the Vienna Ab Initio Simulation Package (VASP) for density functional theory and the YPHON code for phonon calculations. Chapter 6 introduces the modeling of Gibbs energy of phases with the CALPHAD method. Chapter 7 deals with chemical reactions and the Ellingham diagram for metal-oxide systems and presents the calculation of the maximum reaction rate from equilibrium thermodynamics. Chapter 8 is devoted to electrochemical reactions and Pourbaix diagrams with application examples. Chapter 9 concludes this volume with the application of a model of multiple microstates to Ce and Fe3Pt. CALPHAD modeling is briefly discussed in the context of genomics of materials. The book introduces basic thermodynamic concepts clearly and directs readers to appropriate references for advanced concepts and details of software implementation. The list of references is quite comprehensive. The authors make liberal use of diagrams to illustrate key concepts. The two Appendices at the end discuss software requirements and the file structure, and present templates for special quasi-random structures. There is also a link to download pre-compiled binary files of the YPHON code for Linux or Microsoft Windows systems. The exercises at the end of the chapters assume that the reader has access to VASP, which is not freeware. Readers without access to this code can work on a limited number of exercises. However, results from other first principles codes can be organized in the YPHON format as explained in the Appendix. This book will serve as an excellent reference on computational thermodynamics and the exercises provided at the end of each chapter make it valuable as a graduate level textbook. Reviewer: Ram Devanathan is Acting Director of Earth Systems Science Division, Pacific Northwest National Laboratory, USA.

Revision of the genus Ptomaphagus Hellwig from eastern Asia (Coleoptera, Leiodidae, Cholevinae).

Science.gov (United States)

Wang, Cheng-Bin; Perreau, Michel; Růžička, Jan; Nishikawa, Masaaki

2017-01-01

The species belonging to the genus Ptomaphagus Hellwig, 1795 (Coleoptera, Leiodidae, Cholevinae, Ptomaphagini) from eastern Asia are assigned to three species groups. Group yasutoshii has a single species: P. (s. str.) yasutoshii Nishikawa, 1993 from Taiwan, China. Group nepalensis with three species: P. (s. str.) nepalensis Perreau, 1988 from Nepal and P. (s. str.) masumotoi Nishikawa, 2011 from Thailand are redescribed, and P. (s. str.) piccoloi Wang, Růžička, Nishikawa, Perreau & Hayashi, 2016 is recorded for the first time from China (Zhejiang). Group sibiricus with seven species, including two newly described Chinese ones P. (s. str.) funiu sp. n. from Henan, and P. (s. str.) haba sp. n. from Yunnan, and five known species: P. (s. str.) chenggongi Wang, Nishikawa, Perreau, Růžička & Hayashi, 2016, P. (s. str.) hayashii Wang, Růžička, Perreau, Nishikawa & Park, 2016, P. (s. str.) kuntzeni Sokolowski, 1957 (distribution records from Myanmar excluded), P. (s. str.) sibiricus Jeannel, 1934 and P. (s. str.) tingtingtae Wang, Nishikawa, Perreau, Růžička & Hayashi, 2016. Specimens of other undescribed species of the group sibiricus are also recorded, revealing a high diversity of this genus in eastern Asia, especially in central and north Sichuan, China, which essentially remains to be investigated. Relevant morphological characters of the examined species are illustrated with colour plates, and their known distributions are mapped. A key to species of Ptomaphagus from eastern Asia is provided.

New View of Distant Galaxy Reveals Furious Star Formation

Science.gov (United States)

2007-12-01

A furious rate of star formation discovered in a distant galaxy shows that galaxies in the early Universe developed either much faster or in a different way from what astronomers have thought. "This galaxy is forming stars at an incredible rate," said Wei-Hao Wang, an astronomer at the National Radio Astronomy Observatory (NRAO) in Socorro, New Mexico. The galaxy, Wang said, is forming the equivalent of 4,000 Suns a year. This is a thousand times more violent than our own Milky Way Galaxy. Location of Distant Galaxy Visible-light, left (from HST) and Infrared, right, (from Spitzer) Images: Circles indicate location of GOODS 850-5. CREDIT: Wang et al., STScI, Spitzer, NASA, NRAO/AUI/NSF Click on image for high-resolution file (1 MB) The galaxy, called GOODS 850-5, is 12 billion light-years from Earth, and thus is seen as it was only about 1.5 billion years after the Big Bang. Wang and his colleagues observed it using the Smithsonian Astrophysical Observatory's Submillimeter Array (SMA) on Mauna Kea in Hawaii. Young stars in the galaxy were enshrouded in dust that was heated by the stars and radiated infrared light strongly. Because of the galaxy's great distance from Earth, the infrared light waves have been stretched out to submillimeter-length radio waves, which are seen by the SMA. The waves were stretched or "redshifted," as astronomers say, by the ongoing expansion of the Universe. "This evidence for prolific star formation is hidden by the dust from visible-light telescopes," Wang explained. The dust, in turn, was formed from heavy elements that had to be built up in the cores of earlier stars. This indicates, Wang said, that significant numbers of stars already had formed, then spewed those heavy elements into interstellar space through supernova explosions and stellar winds. "Seeing the radiation from this heated dust revealed star formation we could have found in no other way," Wang said. Similar dusty galaxies in the early Universe may contain most of the

In-situ IR monitoring of the formation of Zr-fumarate MOF

CSIR Research Space (South Africa)

Ren, Jianwei

2017-05-01

Full Text Available monitoring of the formation of Zr-fumarate MOF Authors: Jianwei Ren, Nicholas M. Musyoka, Henrietta W. Langmi, Brian C. North, Mkhulu Mathe, Wan Pang, Mingjie Wang, Joseph Walker PII: S0169-4332(17)30296-9 DOI: http://dx.doi.org/doi:10.1016/j.apsusc.2017....01.271 Reference: APSUSC 35066 To appear in: APSUSC Received date: 21-9-2016 Revised date: 20-1-2017 Accepted date: 25-1-2017 Please cite this article as: Jianwei Ren, Nicholas M.Musyoka, Henrietta W.Langmi, Brian C.North, Mkhulu Mathe, Wan Pang, Mingjie Wang...

Argonne Nuclear Data Program

Energy Technology Data Exchange (ETDEWEB)

Kondev, F. [US Nuclear Data Program, U.S. DOE/SC (United States)

2013-08-15

Nuclear Data Compilations and Evaluations: - Nuclear structure and decay data compilations and evaluations for the International NSDD network (ENSDF and XUNDL); - AME12 and NuBase12 - in collaboration with G. Audi and M. MacCormick, CSNSM (Orsay), M. Wang, IMP (Lanzhou) and B. Pfeiffer, GSI (Darmstadt) - presentation by M. Wang; - DDEP coordinator - completed; - Horizontal nuclear data evaluation activities -IAEA CRP's, Isomers, Medical Isotopes; Complementary ND research Activities: - CARIBU, FRIB and other RIB facilities, Gretina, IAEA-CRP - emphasis on nuclear structure physics and astrophysics, and their intersection with applied nuclear physics programs.

Unexpected dehydrogenation behaviors of the 2LiBH4-MgH2 composite confined in a mesoporous carbon scaffold

CSIR Research Space (South Africa)

Wang, K

2014-11-01

Full Text Available Chemistry C Vol. 118(46) Unexpected Dehydrogenation Behaviors of the 2LiBH4−MgH2 Composite Confined in a Mesoporous Carbon Scaffold Kuikui Wang,†,‡ Xiangdong Kang,*,‡ Yujie Zhong,‡ Chaohao Hu,§ Jianwei Ren,⊥ and Ping Wang*,‡ †University... of Science and Technology of China, Hefei 230026, P. R. China ‡Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, P. R. China §Guangxi Key Laboratory of Information Materials...

On the equivalence of LIST and DIIS methods for convergence acceleration

Energy Technology Data Exchange (ETDEWEB)

Garza, Alejandro J. [Department of Chemistry, Rice University, Houston, Texas 77251-1892 (United States); Scuseria, Gustavo E. [Department of Chemistry and Department of Physics and Astronomy, Rice University, Houston, Texas 77251-1892, USA and Chemistry Department, Faculty of Science, King Abdulaziz University, Jeddah 21589 (Saudi Arabia)

2015-04-28

Self-consistent field extrapolation methods play a pivotal role in quantum chemistry and electronic structure theory. We, here, demonstrate the mathematical equivalence between the recently proposed family of LIST methods [Wang et al., J. Chem. Phys. 134, 241103 (2011); Y. K. Chen and Y. A. Wang, J. Chem. Theory Comput. 7, 3045 (2011)] and the general form of Pulay’s DIIS [Chem. Phys. Lett. 73, 393 (1980); J. Comput. Chem. 3, 556 (1982)] with specific error vectors. Our results also explain the differences in performance among the various LIST methods.

Graphene energy storage and conversion applications

CERN Document Server

Liu, Zhaoping

2014-01-01

Series PrefacePrefaceAuthorsGraphene Overview; Xufeng Zhou, Wei Wang, and Zhaoping LiuSynthesis of Graphene; Wei Wang, Hailiang Cao, Xufeng Zhou, and Zhaoping LiuApplications of Graphene in Lithium Ion Batteries; Xufeng Zhou and Zhaoping LiuApplications of Graphene in New-Concept Batteries; Xufeng Zhou and Zhaoping LiuApplications of Graphene in Supercapacitors; Chao Zheng, Xufeng Zhou, Hailiang Cao, and Zhaoping LiuApplications of Graphene in Solar Cells; Fuqiang Huang, Dongyun Wan, Hui Bi, and Tianquan LinApplications of Graphene in Fuel Cells; Xuejun Zhou, Jinli Qiao, and Yuyu LiuIndex.

Antiproton production

International Nuclear Information System (INIS)

Lazarus, D.M.

1987-01-01

The results for the antiproton momentum spectrum produced in proton reactions on lead at the CERN Antiproton Accumulator is scaled to AGS operating conditions using the Sanford-Wang formula with no correction for target material. Yield predictions as a function of momentum are shown for 28.3 GeV protons on beryllium and results are converted to antiproton beam flux. The AGS Medium Energy Separated Beam has a flux which is a factor of 2 lower than Sanford-Wang predictions. This may be due to factors affecting beam acceptance

Interface engineering in inorganic hybrid structures towards improved photocatalysis (Conference Presentation)

Science.gov (United States)

Xiong, Yujie

2016-10-01

Designing new photocatalytic materials for improving photoconversion efficiency is a promising route to alleviate the steadily worsening environmental issues and energy crisis. Despite the invention of a large number of catalytic materials with well-defined structures, their overall efficiency in photocatalysis is still quite limited as the three key steps - light harvesting, charge generation and separation, and charge transfer to surface for redox reactions - have not been substantially improved. To improve each step in the complex process, there is a major trend to develop materials based on inorganic hybrid structures. In this case, interface engineering holds the promise for boosting the overall efficiency, given the key roles of interface structures in charge and energy transfer. In this talk, I will demonstrate several different approaches to designing inorganic hybrid structures with improved photocatalytic performance via interface engineering. The typical demonstrations include semiconductor-plasmonics systems for broad-spectrum light harvesting, metal-semiconductor interfaces for improved charge separation, semiconductor-MOF (metal-organic framework) configurations for activated surface reactions. It is anticipated that this series of works open a new window to rationally designing inorganic hybrid materials for photo-induced applications. References: (1) Bai, S.; Yang, L.; Wang, C.; Lin, Y.; Lu, J.; Jiang, J. and Xiong, Y.*, Angew. Chem. Int. Ed. 54, 14810-14814 (2015). (2) Bai, S.; Jiang, J.; Zhang, Q. and Xiong, Y.*, Chem. Soc. Rev. 44, 2893-2939 (2015). (3) Bai, S.; Li, X.; Kong, Q.; Long, R.; Wang, C.; Jiang, J. and Xiong, Y.*, Adv. Mater. 27, 3444-3452 (2015). (4) Bai, S.; Ge, J.; Wang, L.; Gong, M.; Deng, M.; Kong, Q.; Song, L.; Jiang, J.;* Zhang, Q.;* Luo, Y.; Xie, Y. and Xiong, Y.*, Adv. Mater. 26, 5689-5695 (2014). (5) Li, R.; Hu, J.; Deng, M.; Wang, H.; Wang, X.; Hu, Y.; Jiang, H. L.; Jiang, J.;* Zhang, Q.;* Xie, Y. and Xiong, Y.*, Adv. Mater

CONVERGÊNCIA E TRANSMÍDIA: GALÁXIAS SEMÂNTICAS E NARRATIVAS EMERGENTES EM JORNALISMO

Directory of Open Access Journals (Sweden)

Geane Alzamora

2012-06-01

Full Text Available Este artigo procura discutir as possibilidades de aplicação no Jornalismo do conceito de narrativa transmidiática, proposto por Henry Jenkins (2003 no âmbito das narrativas ficcionais. Aborda inicialmente as definições de Transmedia Storytelling, investiga as diferenças conceituais entre convergência e transmídia e propõe uma abordagem própria do conceito de transmídia no universo jornalístico, fundada na perspectiva do conhecimento produzido em dimensão transmidiática e nas especificidades informacionais dos formatos. Conclui com uma exploração inicial de exemplos de narrativas emergentes no contexto do jornalismo transmidiático, como o Jornalismo de Imersão e os newsgames, sugerindo que o experimentalismo seja um aspecto marcante da narrativa transmídia.

An X-Ray Luminous, Dwarf Seyfert Companion of Markarian 273 (ApJ, 496, L9 [1998])

Science.gov (United States)

Xia, X.-Y.; Boller, Th.; Wu, H.; Deng, Z.-G.; Gao, Y.; Zou, Z.-L.; Mao, S.; Börner, G.

1998-11-01

In the Letter ``An X-Ray Luminous, Dwarf Seyfert Companion of Markarian 273'' by X.-Y. Xia, Th. Boller, H. Wu, Z.-G. Deng, Y. Gao, Z.-L. Zou, S. Mao, and G. Börner (ApJ, 496, L9 [1998]), an observational error occurred that invalidates some of our conclusions. Since Mrk 273x was essentially invisible (B~21) in our acqusition image, in order to position the slit on the faint Mrk 273x, a slit rotation had to be applied. Unfortunately, the amount of rotation was applied incorrectly. As a result, the spectrum obtained (shown in Fig. 2) was not for the intended target, Mrk 273x, but for an object very close to, but northeast of, Mrk 273. A new spectrum of Mrk 273x indicates that Mrk 273x is at redshift 0.458, not at 0.0378 as quoted in the Letter. The larger redshift implies that both the optical and X-ray luminosity have to be revised upward by a factor of ~170. Mrk 273x is therefore not a dwarf galaxy optically. The X-ray properties of Mrk 273x remain the same except that its soft X-ray luminosity now reaches ~1044 ergs s-1 for H0=50 km s-1 Mpc-1. The new observations will be presented in a subsequent paper (X.-Y. Xia et al., in preparation [1998]) in order to make corrections and shed further insights on the objects in the Mrk 273 field.

Book Reivew: A chance for lasting survival: Ecology and behavior of wild giant pandas

Science.gov (United States)

van Manen, Frank T.

2015-01-01

“If we watch species going extinct in front of us, how useful is that we publish 100 or even 1,000 papers by studying them?” (p. 330). This quote from senior author Pan Wenshi captures an important essence of this book. A translation of a 2001 monograph originally published in Chinese, this volume details the findings of a 15-year research program in the Qinling Mountains by Wenshi and his students. Starting in 1984, this Chinese research team from Peking University was only the second to study free-ranging pandas. This is the remarkable journey of a devoted group of field researchers who helped changed the course of giant panda conservation, events that few conservationists outside of China have been aware of until now.Review info: A chance for lasting survival: Ecology and behavior of wild giant pandas. By Pan Wenshi, Lü Zhi, Zhu Xiaojian, Wang Dajun, Wang Hao, Long Yu, Fu Dali, and Zhou Xin; edited by, William J. McShea, Richard B. Harris, David L. Garshelis, and Wang Dajun, 2014. ISBN: 978-1-935623-17-5, 349pp.

Optimal Stopping with Information Constraint

International Nuclear Information System (INIS)

Lempa, Jukka

2012-01-01

We study the optimal stopping problem proposed by Dupuis and Wang (Adv. Appl. Probab. 34:141–157, 2002). In this maximization problem of the expected present value of the exercise payoff, the underlying dynamics follow a linear diffusion. The decision maker is not allowed to stop at any time she chooses but rather on the jump times of an independent Poisson process. Dupuis and Wang (Adv. Appl. Probab. 34:141–157, 2002), solve this problem in the case where the underlying is a geometric Brownian motion and the payoff function is of American call option type. In the current study, we propose a mild set of conditions (covering the setup of Dupuis and Wang in Adv. Appl. Probab. 34:141–157, 2002) on both the underlying and the payoff and build and use a Markovian apparatus based on the Bellman principle of optimality to solve the problem under these conditions. We also discuss the interpretation of this model as optimal timing of an irreversible investment decision under an exogenous information constraint.

Treating cutaneous squamous cell carcinoma using 5-aminolevulinic acid polylactic-co-glycolic acid nanoparticle-mediated photodynamic therapy in a mouse model

Directory of Open Access Journals (Sweden)

Wang X

2015-01-01

Full Text Available Xiaojie Wang,1,2,* Lei Shi,2,* Qingfeng Tu,2 Hongwei Wang,3 Haiyan Zhang,2 Peiru Wang,2 Linglin Zhang,2 Zheng Huang,4 Feng Zhao,5 Hansen Luan,5 Xiuli Wang2 1Shanghai Skin Diseases Clinical College of Anhui Medical University, 2Shanghai Skin Disease Hospital, 3Huadong Hospital, Fudan University, Shanghai, 4MOE Key Laboratory of OptoElectronic Science and Technology for Medicine, Fujian Normal University, Fuzhou, 5National Pharmaceutical Engineering Research Center, China State Institute of Pharmaceutical Industry, Shanghai, People’s Republic of China *These authors contributed equally to this study Background: Squamous cell carcinoma (SCC is a common skin cancer, and its treatment is still difficult. The aim of this study was to evaluate the effectiveness of nanoparticle (NP-assisted 5-aminolevulinic acid (ALA delivery for topical photodynamic therapy (PDT of cutaneous SCC.Materials and methods: Ultraviolet-induced cutaneous SCCs were established in hairless mice. ALA-loaded polylactic-co-glycolic acid (PLGA NPs were prepared and characterized. The kinetics of ALA PLGA NP-induced protoporphyrin IX fluorescence in SCCs, therapeutic efficacy of ALA NP-mediated PDT, and immune responses were examined.Results: PLGA NPs enhanced protoporphyrin IX production in SCC. ALA PLGA NP-mediated topical PDT was more effective than free ALA of the same concentration in treating cutaneous SCC.Conclusion: PLGA NPs provide a promising strategy for delivering ALA in topical PDT of cutaneous SCC. Keywords: 5-aminolevulinic acid (ALA, polylactic-co-glycolic acid (PLGA, nanoparticles (NPs, cutaneous squamous cell carcinoma (SCC, photodynamic therapy (PDT, microneedling

Ortodoxia y heterodoxia en la filosofía de Joseph de Maistre. Sus antecedentes y sus huellas en el pensamiento contrarrevolucionario español (1833-1936)

OpenAIRE

Fornés Murciano, Antonio

2015-01-01

Joseph de Maistre va ser un pensador original, d'una profunditat major de la que freqüentment se li concedeix i posseïdor, a més, d'una prosa excepcional. Aquest estudi pretén mostrar d'una banda que la seva filosofia i la seva lluita a favor de l'ortodòxia polític-religiosa neix, paradoxalment, de fonts obertament heterodoxes, i d'un altre costat que el seu discurs ideològic i antirevolucionari, nodrit per la força d'aquest ascendent, va influir de forma determinant en els apriorismes foname...

Da deflexão de raios cósmicos ultra-energéticos no campo magnético galáctico

OpenAIRE

Rafael Alves Batista

2012-01-01

Resumo: Campos magnéticos cósmicos são ubíquos e estão presentes em todas as escalas, desde os planetas até os superaglomerados de galáxias. Sabe-se que o campo magnético da Via Láctea possui uma componente regular, que tem uma estrutura espiral, e uma componente aleatória. Muitas questões acerca do magnetismo galáctico ainda permanecem sem respostas, e o modelo de espiral mais adequado para descrever as observações é incógnito. Uma possibilidade pouco explorada para estudar o campo magnético...

Analysis on hydrological condition for uranium ore formation in Wuerhe district, Junggar Basin

International Nuclear Information System (INIS)

Zhang Quanqing; Zhang Xinke; Ren Manchuan

2009-01-01

Wuerhe district is located in the northwestern part of Junggar Basin, Xinjiang. It belongs to a relative quiet area without the obvious tectonic activities and obvious subsequent tectonic activization. Through the regional uranium resources evaluation on this area, the inter-bedded oxidation zone and uranium mineralization are discovered in Cretaceous. The wall rock, the recharge-runoff-discharge mechanism of groundwater, palaeo-hydrological condition, hydrological and hydrogeochemical features of groundwater are introduced briefly, the favorable uranium ore-forming segment is summarized to be located in the fore-mountain area to the west of Ke-Xia fault terrace zone. (authors)

The direct effect on geoid computations

OpenAIRE

Juan G. Serpas

2016-01-01

La técnica más popular para la reducción de observaciones gravimétricas al geoide es el método de condensación de Helmert. Dos maneras deferentes de aplicar dicha reducción son estudiadas: el enfoque clásico (Wang y Rapp, 1990, Heiskanen y Morits, 1967) y el enfoque por Vanicek and Kleusberg (1987), extendido por Martinec et al. (1993). El enfoque clásico (Wang y Rapp, 1990, Heiskanen y Moritz, 1967) argumenta que el efecto de la capa condensada tiene que ser evaluado en el geoide y no en el ...

Two new species of the stonefly genus Amphinemura (Insecta, Plecoptera, Nemouridae) from China.

Science.gov (United States)

Ji, Xiao-Yu; Du, Yu-Zhou; Wang, Zhi-Jie

2014-01-01

Two new species of the genus Amphinemura Ris from China are described and illustrated, i.e. A. annulata Du & Ji, sp. n. from Zhejiang, Shanxi, Shaanxi and Guizhou Province, and A. lingulata Du & Wang, sp. n. from Shaanxi and Sichuan Province. A. annulata is similar to A. tricintusidens Wang & Zhu in having an apical cavity of the epiproct, but the epiproct ventral sclerite and the median paraproct lobe of the two species are different. A. lingulata is related to A. didyma Zhu & Yang in having the similar epiproct, but they differ mostly in paraproct median and outer lobes.

Autocrine and Paracrine Hh Signaling Regulate Prostate Development

Science.gov (United States)

2010-09-01

Rev. Mol. Cell. Biol. 6, 306–317 7. Wang, B. E., Shou, J., Ross, S., Koeppen, H., De Sauvage, F. J., and Gao, W. Q. (2003) J. Biol. Chem. 278, 18506...and Placzek, M. (2006) Nat. Rev. Genet. 7, 841–850 13. Callahan, C. A., Ofstad, T., Horng, L.,Wang, J. K., Zhen, H. H., Coulombe , P. A., and Oro, A. E...Albig, A. R., and Schiemann, W. P. (2005)Mol. Biol. Cell 16, 609–625 45. Olsen, M. W., Ley , C. D., Junker, N., Hansen, A. J., Lund, E. L., and Krist

Chlorine isotopic geochemistry of salt lakes in the Qaidam Basin, China

Digital Repository Service at National Institute of Oceanography (India)

Liu, W.G.; Xiao, Y.K.; Wang, Q.Z.; Qi, H.P.; Wang, Y.H.; Zhou, Y.M.; Shirodkar, P.V.

*Cl+ ion. Int. J. Mass Spectrom. Ion Process., 116: crysatallization of saline minerals in salt lake. J. Salt Lake 183-192. Sci., 2: 35-40 (in Chinese). Xiao, Y.K., Sun, D.P., Wang, Y.H., Qi, H.P. and Jin, L., 1992. Boron isotopic compositions of brine..., sediments, and source water in Da Qaidam Lake, Qinghai, China. Geochim. Cos- mochim. Acta, 56: 1.561-1568. Xiao, Y.K., Jin, L., Liu. W.G., Qi, H.P., Wang, W.H. and Sun, D.P., 1994a. The isotopic compositions of chlorine in Da Qaidam Lake. Chin. Sci...

Frontiers in biochip technology

National Research Council Canada - National Science Library

Xing, Wan-Li; Cheng, Jing

2006-01-01

... . . . . . . . . . . . . . . . . . . . . . . . . . . . . Haiching Ma, Yuan Wang, Amy S. Pomaybo, and Connie Tsai 2. Improvement of Microarray Technologies for Detecting Single Nucleotide Mismatch...

Ranitidine reduced levodopa-induced dyskinesia in a rat model of Parkinson’s disease

Directory of Open Access Journals (Sweden)

Cui G

2013-12-01

Full Text Available Guiyun Cui,1,* Xinxin Yang,1,* Xiaoying Wang,2,* Zunsheng Zhang,1 Xuanye Yue,1 Hongjuan Shi,1 Xia Shen11Department of Neurology, 2Department of Ultrasound, the Affiliated Hospital of Xuzhou Medical College, Jiangsu, People’s Republic of China *These authors contributed equally to this workBackground: Chronic administration of levodopa in Parkinson’s disease leads to debilitating involuntary movements, termed levodopa-induced dyskinesia (LID. The pathogenesis of LID is poorly understood. Previous research has shown that histamine H2 receptors are highly expressed in the input (striatum and output (globus pallidus, substantia nigra regions of the basal ganglia, particularly in the GABAergic striatopallidal and striatonigral pathways. Therefore, a histamine H2 receptor antagonist could be used to reduce LID. In the present work, we investigated whether ranitidine has the potential to diminish LID in rats with dyskinesia and explored the underlying mechanisms involved.Methods: A rat model of PD was induced by 6-hydroxydopamine. Valid PD rats were then treated with levodopa (25 mg/kg, intraperitoneally and benserazide (12.5 mg/kg, intraperitoneally for 21 days to induce a rat model of LID. The acute and chronic effects of administration of ranitidine at different doses (5 mg/kg, 10 mg/kg, and 20 mg/kg on abnormal involuntary movements, levodopa-induced rotations, and the forelimb adjusting steps test were investigated in LID rats. The chronic effect of ranitidine (10 mg/kg on the expression of Arc and proenkephalin was also evaluated.Results: Levodopa elicited increased dyskinesia in PD rats. Acute ranitidine treatment had no effect on LID, but chronic ranitidine administration (10 mg/kg, 20 mg/kg reduced LID in rats with dyskinesia. Importantly, levodopa-induced rotations were not affected by chronic treatment with ranitidine. In addition, chronic ranitidine (10 mg/kg, 20 mg/kg significantly improved stepping of the lesioned forepaw. Real

Ultrasound-targeted stromal cell-derived factor-1-loaded microbubble destruction promotes mesenchymal stem cell homing to kidneys in diabetic nephropathy rats

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Wu S

2014-12-01

Full Text Available Shengzheng Wu,1 Lu Li,1 Gong Wang,1 Weiwei Shen,2 Yali Xu,1 Zheng Liu,1 Zhongxiong Zhuo,1 Hongmei Xia,1 Yunhua Gao,1 Kaibin Tan1 1Department of Ultrasound, 2Department of Orthopedics, Xinqiao Hospital, Third Military Medical University, Chongqing, People’s Republic of China Abstract: Mesenchymal stem cell (MSC therapy has been considered a promising strategy to cure diabetic nephropathy (DN. However, insufficient MSCs can settle in injured kidneys, which constitute one of the major barriers to the effective implementation of MSC therapy. Stromal cell-derived factor-1 (SDF-1 plays a vital role in MSC migration and involves activation, mobilization, homing, and retention, which are presumably related to the poor homing in DN therapy. Ultrasound-targeted microbubble destruction has become one of the most promising strategies for the targeted delivery of drugs and genes. To improve MSC homing to DN kidneys, we present a strategy to increase SDF-1 via ultrasound-targeted microbubble destruction. In this study, we developed SDF-1-loaded microbubbles (MBSDF-1 via covalent conjugation. The characterization and bioactivity of MBSDF-1 were assessed in vitro. Target release in the targeted kidneys was triggered with diagnostic ultrasound in combination with MBSDF-1. The related bioeffects were also elucidated. Early DN was induced in rats with streptozotocin. Green fluorescent protein-labeled MSCs were transplanted intravenously following the target release of SDF-1 in the kidneys of normal and DN rats. The homing efficacy was assessed by detecting the implanted exogenous MSCs at 24 hours. The in vitro results showed an impressive SDF-1 loading efficacy of 79% and a loading content of 15.8 µg/mL. MBSDF-1 remained bioactive as a chemoattractant. In the in vivo study, SDF-1 was successfully released in the targeted kidneys. The homing efficacy of MSCs to DN kidneys after the target release of SDF-1 was remarkably ameliorated at 24 hours compared with

Successful in vivo hyperthermal therapy toward breast cancer by Chinese medicine shikonin-loaded thermosensitive micelle

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Su Y

2017-05-01

Full Text Available Yonghua Su,1,* Nian Huang,1,* Di Chen,2,* Li Zhang,2,* Xia Dong,2 Yun Sun,2 Xiandi Zhu,2 Fulei Zhang,2 Jie Gao,2 Ying Wang,2 Kexing Fan,2 Puichi Lo,3 Wei Li,2 Changquan Ling1 1Department of Integrative Oncology, Changhai Hospital of Traditional Chinese Medicine, 2International Joint Cancer Institute, The Second Military Medical University, Shanghai, 3Department of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong, China *These authors contributed equally to this work Abstract: The Chinese traditional medicine Shikonin is an ideal drug due to its multiple targets to tumor cells. But in clinics, improving its aqueous solubility and tumor accumulation is still a challenge. Herein, a copolymer with tunable poly(N-isopropylacrymaide and polylactic acid block lengths is designed, synthesized, and characterized in nuclear magnetic resonance. The corresponding thermosensitive nanomicelle (TN with well-defined core-shell structure is then assembled in an aqueous solution. For promoting the therapeutic index, the physical-chemistry properties of TNs including narrow size, low critical micellar concentration, high serum stability, tunable volume phase transition temperature (VPTT, high drug-loading capacity, and temperature-controlled drug release are systematically investigated and regulated through the fine self-assembly. The shikonin is then entrapped in a degradable inner core resulting in a shikonin-loaded thermosensitive nanomicelle (STN with a VPTT of ~40°C. Compared with small-molecular shikonin, the in vitro cellular internalization and cytotoxicity of STN against breast cancer cells (Michigan Cancer Foundation-7 are obviously enhanced. In addition, the therapeutic effect is further enhanced by the programmed cell death (PCD specifically evoked by shikonin. Interestingly, both the proliferation inhibition and PCD are synergistically promoted as T > VPTT, namely the temperature-regulated passive targeting. Consequently, as

Randomized double-blind trial of prophylactic topical Evozac® Calming Skin Spray for gefitinib-associated acne-like eruption

Directory of Open Access Journals (Sweden)

Wang Y

2014-07-01

Full Text Available Yalan Wang,* Yunpeng Yang,* Jinxia Xu, Juan Yu, Xia Liu, Ruizhen Gao, Li Zhang State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China *These authors contributed equally to this work Background: "Gefitinib" is a first-generation epidermal growth factor receptor tyrosine-kinase inhibitor. More than half of patients receiving gefitinib develop acne-like eruption. Evozac® Calming Skin Spray (Evaux Laboratoires, Évaux-les-Bains, France is made of Évaux thermal spring water and commonly used for the treatment of dermatological toxicities caused by anti- epidermal growth factor receptor therapy. The aim of the study reported here was to test the effect of Evozac Calming Skin Spray on the prevention of rash in patients receiving gefitinib. Methods: Non-small-cell lung cancer patients preparing to initiate gefitinib therapy were randomly assigned to apply Evozac Calming Skin Spray or physiological saline to the face three times a day. The treatment was started on the same day as initiation of gefitinib therapy and continued for 4 weeks. Results: A total of 51 patients in the Evozac Calming Skin Spray group and 50 patients in the physiological saline group completed the study per the protocol. The number of facial lesions peaked at the end of 3 weeks in both groups. There were significantly fewer lesions in the Evozac Calming Skin Spray group than in the physiological saline group at the end of 1 week (0.25 versus [vs] 1.10, P=0.031 and 3 weeks (6.67 vs 12.26, P=0.022. Patients from the Evozac Calming Skin Spray group also developed fewer facial lesions at the end of 2 weeks and 4 weeks, however, the difference was not statistically significant. At the end of 4 weeks, fewer patients from the Evozac Calming Skin Spray group developed rash of grade 2 or greater severity (17.6% vs 36.0%, P=0.037, or experienced rash

Extreme soil erosion rates in citrus slope plantations and control strategies. A literature review

Science.gov (United States)

Cerdà, Artemi; Ángel González Peñaloza, Félix; Pereira, Paulo; Reyes Ruiz Gallardo, José; García Orenes, Fuensanta; Burguet, María

2013-04-01

approach. Catena, 85 (3), 231-236. Cerdà, A., Jurgensen, M.F., Bodi, M.B. 2009. Effects of ants on water and soil losses from organically-managed citrus orchards in eastern Spain. Biologia, 64 (3), 527-531. Cerdà, A., Morera, A.G., Bodí, M.B. 2009. Soil and water losses from new citrus orchards growing on sloped soils in the western Mediterranean basin. Earth Surface Processes and Landforms, 34 (13), 1822-1830. Lavigne, C., Achard, R., Tixier, P., Lesueur Jannoyer, M. 2012. How to integrate cover crops to enhance sustainability in banana and citrus cropping systems. Acta Horticulturae, 928, 351-358. Le Bellec, F., Damas, O., Boullenger, G., Vannière, H., Lesueur Jannoyer, M., Tournebize, R., Ozier Lafontaine, H. 2012. Weed control with a cover crop (Neonotonia wightii) in mandarin orchards in Guadeloupe (FWI). Acta Horticulturae, 928, 359-366. Liu, Y., Tao, Y., Wan, K.Y., Zhang, G.S., Liu, D.B., Xiong, G.Y., Chen, F. 2012. Runoff and nutrient losses in citrus orchards on sloping land subjected to different surface mulching practices in the Danjiangkou Reservoir area of China. Agricultural Water Management, 110, 34-40. Lu, J., Wilson, M.J., Yu, J. 1997. Effects of trench planting and soil chiselling on soil properties and citrus production in hilly ultisols of China Soil and Tillage Research, 43 (3-4), 309-318. Lü, W., Zhang, H., Wu, Y., Cheng, J., Li, J., Wang, X. 2012. The impact of plant hedgerow in Three Gorges on the soil chemicophysical properties and soil erosion. Key Engineering Materials, 500, 142-148. Wang, L., Tang, L., Wang, X., Chen, F. 2010. Effects of alley crop planting on soil and nutrient losses in the citrus orchards of the Three Gorges Region. Soil and Tillage Research, 110 (2), 243-250. Wu J., Li Q., Yan L. 1997. Effect of intercropping on soil erosion in young citrus plantation - a simulation study. Chinese Journal of Applied Ecology, 8 (2), 143-146. Wu, D.-M., Yu, Y.-C., Xia, L.-Z., Yin, S.-X., Yang, L.-Z. 2011. Soil fertility indices of citrus

NASA Child Fitness Promotion Program in Young Children in South Korea

Science.gov (United States)

Min, Jungwon; Kim, Gilsook; Lim, Hyunjung; Carvajal, Nubia A.; Lloyd, Charles W.; Wang, Youfa

2015-01-01

Childhood obesity is a serious global public health concern (WHO, 2015; Wang Y & Lobstein T, 2006). Low self-esteem and related mental health problems are common in obese children (Strauss RS, 2000) as well as poor academic performance and career development (Gurley-Calvez T, 2010).Westernized dietary habits and sedentary lifestyles are identified as the major risk factors of current alarming rate of obesity along with genetic susceptibility (Popkin BM, 1999). Children in many countries, including South Korea, have become increasingly sedentary due to urbanization changes in their respective societies (Ng SW, et al. 2009, Salmon J et al. 2011). In particular, South Korea had abundant dissemination of mobile technology, such as tablet and smart phone devices. Children have become reliant on mobile devices and are less likely to perform physical activities (Do, et al, 2013). Effective and sustainable intervention programs are needed to fight the global obesity epidemic (IOM, 2012; Wang Y et al, 2013; Wang Y et al, 2015). Previous studies suggested focus on prevention strategies that begin in early childhood, a period when children establish their life habits. (Salmon J et al. 2011). Recent systematic reviews and meta-analysis including ours found that obesity prevention programs for young children have a greater intervention effect (Waters E, et al, 2011; Wang Y et al, 2013; Wang Y et al, 2015). The NASA Mission X: Train Like an Astronaut (MX) program was developed to promote children's exercise and healthy eating with excitement for training like an astronaut (Lloyd C, 2012).At present, the NASA MX Program covered 28 countries, enrolled children through their teachers in school setting (MX report 2014, 2015). This pilot study adapted the NASA MX intervention program for young children in South Korea. We assessed its feasibility and effectiveness in promoting physical activity (PA) in children and in improving parents' perspectives. We also examined the status of PA

A new index for identifying different types of El Niño Modoki events

Science.gov (United States)

Wang, Xin; Tan, Wei; Wang, Chunzai

2018-04-01

El Niño Modoki events can be further classified into El Niño Modoki I and II in terms of their opposite impacts on southern China rainfall (Wang and Wang, J Clim 26:1322-1338, 2013) and the Indian Ocean dipole mode (Wang and Wang, Clim Dyn 42:991-1005, 2014). The present paper develops an index to identify the types of El Niño events. The El Niño Modoki II (MII) index is defined as the leading principle component of multivariate empirical orthogonal function analysis of the normalized El Niño Modoki index, Niño4 index and 850 hPa relative vorticity anomalies averaged near the Philippine Sea during autumn. The MII index exhibits dominant variations on interannual (2-3 and 4-5 years) and decadal (10-20 years) timescales. El Niño Modoki II events can be well identified by using the MII index value being larger than 1 standard deviation. Further analyses and numerical model experiments confirm that the MII index can portray the major oceanic and atmospheric features of El Niño Modoki II events. The constructed MII index along with previous ENSO indices can be used for classifying and identifying all types of El Niño events. Because of distinct impacts induced by different types of El Niño events, the implication of the present study is that climate prediction and future climate projection under global warming can be improved by using the MII index and other indices to identify the types of El Niño events.

Laser Spectroscopy of Ruthenium Containing Diatomic Molecules: RuH/D and RuP.

Science.gov (United States)

Adam, Allan G.; Konder, Ricarda M.; Nickerson, Nicole M.; Linton, Colan; Tokaryk, D. W.

2015-06-01

In the last few years, the Cheung group in Hong Kong and the Steimle group in Arizona have successfully studied several ruthenium containing diatomic molecules, RuX (X =C, O, N, B, using the laser-ablation molecular jet technique. Based on this success, the UNB spectroscopy group decided to try and find the optical signatures of other RuX molecules. Using CH_3OH and PH_3 as reactant gases, the RuH and RuP diatomic molecules have been detected in surveys of the 420 - 675 nm spectral region. RuD has also been made using fully deuterated methanol as a reactant. Dispersed fluorescence experiments have been performed to determine ground state vibrational frequencies and the presence of any low-lying electronic states. Rotationally resolved spectra for these molecules have also been taken and the analysis is proceeding. The most recent results will be presented. F. Wang et al., Journal of Chemical Physics 139, 174318 (2013). N. Wang et al., Journal of Physical Chemistry A 117, 13279 (2013). T. Steimle et al., Journal of Chemical Physics 119, 12965 (2003). N. Wang et al., Chemical Physics Letters 547, 21 (2012).

Género y nivel educativo en las narrativas autobiográficas de la infancia

Directory of Open Access Journals (Sweden)

Marcia Leticia Ruíz Cansino

2012-11-01

Full Text Available The present work deals with autobiographic memory, educative background and gender roles. It is based in socio–cultural psychology research supporting the relationship between context and the development of cognitive processes. 96 structured interviews were made in Cd. Victoria, Tamaulipas to men and women with different educative background: literacy, basic education and university, they ranged between 30 and 55 years old. Personal recollections analysis is based in the categories proposed by Wang (Wang 2001, Wang y Conway 2004. Roles of main characters present in the autobiographical narratives were also investigated using family, educational, work, recreational, and sport contexts. The results shows that women childhood narratives centered in social themes, it has more emotional expresions and the roles are related to child care, domestic work and the enjoyment of school work. Men narratives content is about their own wishes and interests, it has less emotional verbal expressions, they are prone to help with child care but not with domestic work, besides, they show a bigger interest in sports. It was also found that the greater the educative background, the larger the narrative production.

The state of research after 25 years of Nanotechnology

Science.gov (United States)

Demming, Anna

2013-01-01

Discussions%20podcasts [2] 25th Volume Special Issue http://iopscience.iop.org/0957-4484/25/1 [3] Lee S-K, Humayun Kabir S M, Sharma B K, Kim B J, Cho J H and Ahn J-H 2014 Photo-patternable ion gel-gated graphene transistors and inverters on plastic Nanotechnology 25 014002 [4] Park S, Yun J M, Maiti U N, Moon H-S, Jin H M and Kim S O 2014 Device-oriented graphene nanopatterning by mussel-inspired directed block copolymer self-assembly Nanotechnology 25 014008 [5] Li Y, Nagato K, Delaunay J-J, Kubota J and Domen K 2014 Fabrication of highly ordered Ta2O5 and Ta3N5 nanorod arrays by nanoimprinting and through-mask anodization Nanotechnology 25 014013 [6] Lu P, Lu N, Wang J, Kim M J and Xia Y 2014 Site-selective sulfurization of bromide-capped palladium nanocubes by polysulfide and the underlying mechanism Nanotechnology 25 014003 [7] Lin Y, Zeng B, Ji Y, Liang W, Feng D, Gao M, Zhang Y, Chen X, Chen B and Chen C 2014 Nucleation dynamics of nanostructural TiO2 films with controllable phases on (001) LaAlO3 Nanotechnology 25 014014 [8] Special issue on Organic Photovoltaics http://iopscience.iop.org/0957-4484/24/48 [9] Rudenko A E, Latif A A and Thompson B 2014 Influence of β-linkages on morphology and performance of DArP P3HT-PC61BM solar cells Nanotechnology 25 014005 [10] Grover G N, Rao N and Christman K L 2014 Myocardial matrix-polyethylene glycol hybrid hydrogels for tissue engineering Nanotechnology 25 014011 [11] Kim T and Hyeon T 2014 Applications of inorganic nanoparticles as therapeutic agents Nanotechnology 25 012001 [12] Moran C H, Rycenga M, Xia X, Cobley C M and Xia Y 2014 Using well-defined Ag nanocubes as substrates to quantify the spatial resolution and penetration depth of SERS imaging Nanotechnology 25 014007

Adaptive feedback synchronization of Lue system

International Nuclear Information System (INIS)

Han, X.; Lu, J.-A.; Wu, X.

2004-01-01

This letter further improves and extends the works of Chen and Lue [Chaos, Solitons and Fractals 14 (2002) 643] and Wang et al. [Phys. Lett. A 312 (2003) 34]. In detail, the linear feedback synchronization and adaptive feedback synchronization for Lue system are discussed. And the lower bound of the feedback gain in linear feedback synchronization is presented. The adaptive feedback synchronization with only one controller is designed, which improves the proof in the work by Wang et al. The adaptive synchronization with two controllers for completely uncertain Lue system is also discussed, which extends the work of Chen and Lue. Also, numerical simulations show the effectiveness of these methods

Pollen Flora of Yuenyang Lake Nature Preserve, Taiwan (IV

Directory of Open Access Journals (Sweden)

Yu-Fa Wang

2002-06-01

Full Text Available Yuenyang Lake is an acidic lake situated within a nature preserve in northern Taiwan. The pollen of nineteen taxa, belonging to five families, was collected from this nature preserve and investigated with light and scanning electron microscopy. The results of this investigation are supplementary work to the previous publications in this journal (Chen and Wang, 1999, 2001; Wang and Chen, 2001. A total of 4 pollen classes were identified on the basis of the aperture on the pollen wall: 3-colpate, 6-colpate, 3-colporate, and 4-7-colporate pollen. These results could be useful in the reconstruction of vegetation history around the Yuenyang Lake.

Entropic sampling in the path integral Monte Carlo method

International Nuclear Information System (INIS)

Vorontsov-Velyaminov, P N; Lyubartsev, A P

2003-01-01

We have extended the entropic sampling Monte Carlo method to the case of path integral representation of a quantum system. A two-dimensional density of states is introduced into path integral form of the quantum canonical partition function. Entropic sampling technique within the algorithm suggested recently by Wang and Landau (Wang F and Landau D P 2001 Phys. Rev. Lett. 86 2050) is then applied to calculate the corresponding entropy distribution. A three-dimensional quantum oscillator is considered as an example. Canonical distributions for a wide range of temperatures are obtained in a single simulation run, and exact data for the energy are reproduced

Regenerative engineering

CERN Document Server

Laurencin, Cato T

2013-01-01

Regenerative Engineering: The Future of Medicine Saadiq F. El-Amin III , MD , PhD; Joylene W.L. Thomas, MD ; Ugonna N. Ihekweazu, MD ; Mia D. Woods, MS; and Ashim Gupta, MSCell Biology Gloria Gronowicz, PhD and Karen Sagomonyants, DMDStem Cells and Tissue Regeneration Kristen Martins-Taylor, PhD; Xiaofang Wang, MD , PhD; Xue-Jun Li, PhD; and Ren-He Xu, MD , PhDIntroduction to Materials Science Sangamesh G. Kumbar, PhD and Cato T. Laurencin, MD , PhDBiomaterials A. Jon Goldberg, PhD and Liisa T. Kuhn, PhDIn Vitro Assessment of Cell-Biomaterial Interactions Yong Wang, PhDHost Response to Biomate

Oxigenoterapia hiperbárica

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Francisco Costa

1996-03-01

Full Text Available RESUMO: A Oxigenoterapia Hiperbárica (OHB é um método terapêutico que consiste na administração por via inalatória de oxigénio a uma pressão superior à pressão atmosférica.O objectivo da OHB é reduzir a hipóxia tecidular (seja ela de causa vascular, traumática, tóxica ou infecciosa através de uma importante elevação da pressão parcial de oxigénio.As suas indicaçõs incluem, entre outras, intoxicações pelo monóxido de carbono, acidentes de mergulho (doença de descompressão, embolias gasosas arterials, gangrena gasosa, osteomielite refractária, isquemia traumática aguda, feridas crónicas e queimaduras.Embora dispendiosa, a sua capacidade de reduzir a morbilidade dependente de lesões tecidulares agudas ou crónicas, pode revelar-se economicamente compensadora. SUMMARY: Hyperbaric oxygen (OHB therapy is the intermittent administration of 100% oxygen at a pressure greater than sea levelThe object of OHB is to reduce peripheral tissue hipoxia (vascular, traumatic, toxic or infectious by increasing the tissue oxygen levels.The indications for OHB include carbon monoxide poisoning, diving accidents (decompression sickness, gas embolism, gas gangrene, refractory osteomyelitis, acute traumatic ischemia, chronic wounds and thermal burns.Although hyperbaric therapy is costly, the ability to reduce morbidity associated with acute and chronic tissue injury can be cost effective. Palavras Chave: Hipóxia tecidular, oxigenoterapia hiperbárica, indicações, Key-Words: Peripheral tissue hypoxia, hyperbaric oxygen therapy, indications

First test results of the digital data acquisition at the HORUS spectrometer

International Nuclear Information System (INIS)

Hennig, Andreas; Elvers, Michael; Endres, Janis; Fransen, Christoph; Mayer, Jan; Netterdon, Lars; Pascovici, Gheorghe; Pickstone, Simon Glynn; Scholz, Philipp; Warr, Nigel; Weinert, Michael; Zilges, Andreas

2013-06-01

The HORUS spectrometer at the 10 MV Tandem accelerator at the Institute for Nuclear Physics in Cologne consists of 14 high-purity germanium γ -ray detectors. To extend the experimental opportunities, the new silicon-detector array SONIC was designed, housing eight ΔE-E sandwich silicon detectors for charged-particle spectroscopy. In order to efficiently process all 30 detector signals, the analog data acquisition was replaced by a digital one using the commercially available DGF- 4C modules from the company XIA. The new data acquisition system was tested in various off-beam measurements and two in-beam experiments, focusing on energy and timing resolution. (authors)

Análise Não-ETL de Estrelas do Disco Galáctico - Tese de Doutorado

OpenAIRE

Bragança, Gustavo

2017-01-01

Neste trabalho, analisamos espectros de alta resolução de uma grande amostra de estrelas OB do disco galáctico a fim de estudar a distribuição de velocidade rotacional projetada (vseni) e a distribuição radial de abundâncias no disco externo Galáctico.A distribuição de vseni de estrelas OB da Galáxia é bimodal.Ao separaramos as estrelas em objetos de campo, associação ou de aglomerado, notamos que a distribuição da velocidade rotacional é diferente para cada conjunto, sendo a velocidade média...

Radon daughter plate-out measurements at SNOLAB for polyethylene and copper

Energy Technology Data Exchange (ETDEWEB)

Stein, Matthew; Bauer, Dan; Bunker, Ray; Calkins, Rob; Cooley, Jodi; Loer, Ben; Scorza, Silvia

2018-02-01

Polyethylene and copper samples were exposed to the underground air at SNOLAB for approximately three months while several environmental factors were monitored. Predictions of the radon-daughter plate-out rate are compared to the resulting surface activities, obtained from high-sensitivity measurements of alpha emissivity using the XIA UltraLo-1800 spectrometer at SMU. From these measurements, we determine an average $^{210}$Pb plate-out rate of 249 and 423~atoms/day/cm$^{2}$ for polyethylene and copper, respectively, when exposed to radon activity of 135 Bq/m$^{3}$ at SNOLAB. A time-dependent model of alpha activity is discussed for these materials placed in similar environmental conditions.

The Chemical Constituents and Pharmacological Actions of Cordyceps sinensis

Science.gov (United States)

Liu, Yi; Wang, Jihui; Wang, Wei; Zhang, Hanyue; Zhang, Xuelan; Han, Chunchao

2015-01-01

Cordyceps sinensis, also called DongChongXiaCao (winter worm, summer grass) in Chinese, is becoming increasingly popular and important in the public and scientific communities. This study summarizes the chemical constituents and their corresponding pharmacological actions of Cordyceps sinensis. Many bioactive components of Cordyceps sinensis have been extracted including nucleoside, polysaccharide, sterol, protein, amino acid, and polypeptide. In addition, these constituents' corresponding pharmacological actions were also shown in the study such as anti-inflammatory, antioxidant, antitumour, antiapoptosis, and immunomodulatory actions. Therefore can use different effects of C. sinensis against different diseases and provide reference for the study of Cordyceps sinensis in the future. PMID:25960753

Bond charge approximation for valence electron density in elemental semiconductors

International Nuclear Information System (INIS)

Bashenov, V.K.; Gorbachov, V.E.; Marvakov, D.I.

1985-07-01

The spatial valence electron distribution in silicon and diamond is calculated in adiabatic bond charge approximation at zero temperature when bond charges have the Gaussian shape and their tensor character is taken into account. An agreement between theory and experiment has been achieved. For this purpose Xia's ionic pseudopotentials and Schulze-Unger's dielectric function are used. By two additional parameters Asub(B) and Zsub(B)sup(') we describe the spatial extent of the bond charge and local-field corrections, respectively. The parameter Zsub(B)sup(') accounts for the ratio between the Coulomb and exchange correlation interactions of the valence electrons and its silicon and diamond values have different signs. (author)

Análise do comportamento do hemometabolismo cerebral durante endarterectomia carotídea com pinçamento transitório Análisis del comportamiento del hemometabolismo cerebral durante endarterectomia carotídea con pinzamiento transitorio Analysis of brain hemometabolism behavior during carotid endarterectomy with temporary clamping

OpenAIRE

Gastão Fernandes Duval Neto; Augusto H. Niencheski

2004-01-01

JUSTIFICATIVA E OBJETIVOS: A endarterectomia carotídea com pinçamento transitório altera a relação entre o fluxo sangüíneo cerebral e a demanda metabólica cerebral de oxigênio, com conseqüente geração de uma tendência a hipóxia oliguêmica ou desacoplamento hemometabólico. O objetivo do presente estudo foi identificar as alterações do hemometabolismo cerebral, avaliados através das alterações da saturação da oxihemoglobina no bulbo da veia jugular interna (SjO2), durante endarterectomia carotí...

Análise do comportamento do hemometabolismo cerebral durante endarterectomia carotídea com pinçamento transitório

OpenAIRE

Duval Neto, Gastão Fernandes; Niencheski, Augusto H.

2004-01-01

JUSTIFICATIVA E OBJETIVOS: A endarterectomia carotídea com pinçamento transitório altera a relação entre o fluxo sangüíneo cerebral e a demanda metabólica cerebral de oxigênio, com conseqüente geração de uma tendência a hipóxia oliguêmica ou desacoplamento hemometabólico. O objetivo do presente estudo foi identificar as alterações do hemometabolismo cerebral, avaliados através das alterações da saturação da oxihemoglobina no bulbo da veia jugular interna (SjO2), durante endarterectomia carotí...