SmartHeart CABG Edu

Directory of Open Access Journals (Sweden)

Gabriele DI GIAMMARCO

2015-12-01

Full Text Available The paper reports on the SmartHeart CABG Edu Android app. The app was conceived to be an innovative and up-to-date tool for patient education, the first of its kind in the Italian context. In particular, the app was developed to provide educational material for patients about to undergo Coronary Artery Bypass Graft (CABG surgery, a set of self-assessment tools concerning health status (i.e., BMI calculator, LDL cholesterol calculator and anxiety assessment tool and usability questionnaires (i.e., SEQ and SUS. The paper initially describes the app, then reports on its evaluation, concerning both the app usability and the pre-operative anxiety, and ends by showing the improvements -- derived from the usability evaluation -- put into practice.

How "Edu-Babble" Turns Pupils into "Customers"

Science.gov (United States)

Chitty, Clyde

2009-01-01

The Report of the Nuffield Review of 14-19 education, described by its Lead Director Professor Richard Pring of Oxford University in the last number of FORUM (Volume 51, Number 2 http://dx.doi.org/10.2304/forum.2009.51.2.197), highlights the increasing use of what can be described as "edu-dabble" by sectors of the education establishment.

TVB-EduPack - An interactive learning and scripting platform for The Virtual Brain

Directory of Open Access Journals (Sweden)

Henrik eMatzke

2015-11-01

Full Text Available The Virtual Brain (TVB; www.thevirtualbrain.org is a neuroinformatics platform for full brain network simulation based on individual anatomical connectivity data. The framework addresses clinical and neuroscientific questions by simulating multi-scale neural dynamics that range from local population activity to large-scale brain function and related macroscopic signals like electroencephalography and functional magnetic resonance imaging. TVB is equipped with a graphical and a command-line interface to create models that capture the characteristic biological variability to predict the brain activity of individual subjects. To enable researchers from various backgrounds a quick start into TVB and brain network modelling in general, we developed an educational module: TVB-EduPack. EduPack offers two educational functionalities that seamlessly integrate into TVB’s graphical user interface (GUI: (i interactive tutorials introduce GUI elements, guide through the basic mechanics of software usage and develop complex use-case scenarios; animations, videos and textual descriptions transport essential principles of computational neuroscience and brain modelling; (ii an automatic script generator records model parameters and produces input files for TVB’s Python programming interface; thereby, simulation configurations can be exported as scripts that allow flexible customization of the modelling process and self-defined batch- and post-processing applications while benefitting from the full power of the Python language and its toolboxes. This article covers the implementation of TVB-EduPack and its integration into TVB architecture. Like TVB, EduPack is an open source community project that lives from the participation and contribution of its users. TVB-EduPack can be obtained as part of TVB from thevirtualbrain.org.

Uuringud tõstavad Eesti e-edu poolest esirinda / Henrik Roonemaa

Index Scriptorium Estoniae

Roonemaa, Henrik

2004-01-01

Economist Intelligence Unit'i uuringust riikide e-valmiduse kohta ja e-Business W@atch'i aruandest, milles võrreldi Euroopa firmade edu IT ning tehnoloogia kasutamist äris. Lisa: Eesti embab e-ajastut

IDES-EDU: Comprehensive multidisciplinary education programme to accelerate the implementation of EPBD in Europe

DEFF Research Database (Denmark)

Wyckmans, Annemie; Almeida, Manuela; Brunsgaard, Camilla

are expected learning outcomes, level of integration in existing curricula and alignment with theory and assessment methods. Measures for improvement as well as further dissemination to other European educational facilities are proposed. In this manner, the project will contribute to make the multiple......This paper presents a new education and training programme on integrated energy design developed by fifteen European universities collaborating within the IDES-EDU project (2010-2013), funded by Intelligent Energy Europe. IDES-EDU aims to accelerate the implementation of the Energy Performance...... of Buildings Directive (EPBD) by proposing Master and Post Graduate education and training in multidisciplinary teams. To speed up transition from traditional, sub-optimised building projects with discipline-oriented, segregated budgets and operations, IDES-EDU developed comprehensive, multidisciplinary...

IAU astroEDU: an open-access platform for peer-reviewed astronomy education activities

Science.gov (United States)

Heenatigala, Thilina; Russo, Pedro; Strubbe, Linda; Gomez, Edward

2015-08-01

astroEDU is an open access platform for peer-reviewed astronomy education activities. It addresses key problems in educational repositories such as variability in quality, not maintained or updated regularly, limited content review, and more. This is achieved through a peer-review process similar to what scholarly articles are based on. Activities submitted are peer-reviewed by an educator and a professional astronomer which gives the credibility to the activities. astroEDU activities are open-access in order to make the activities accessible to educators around the world while letting them discover, review, distribute and remix the activities. The activity submission process allows authors to learn how to apply enquiry-based learning into the activity, identify the process skills required, how to develop core goals and objectives, and how to evaluate the activity to determine the outcome. astroEDU is endorsed by the International Astronomical Union meaning each activity is given an official stamp by the international organisation for professional astronomers.

My Dream, My World

Institute of Scientific and Technical Information of China (English)

Joseph DeVeto; 赵惠妙

2005-01-01

@@ I often dream the same dream: I am driving together with my mother on a stretched straight path1.The birds are singing and playing2 around the car, the flowers are opening3 richly4 which decorate5 the land.The breeze is flirting with ourhair, my long, black waterfall and my mother's short gray hair6.

SAR-EDU - An education initiative for applied Synthetic Aperture Radar remote sensing

Science.gov (United States)

Eckardt, Robert; Richter, Nicole; Auer, Stefan; Eineder, Michael; Roth, Achim; Hajnsek, Irena; Walter, Diana; Braun, Matthias; Motagh, Mahdi; Pathe, Carsten; Pleskachevsky, Andrey; Thiel, Christian; Schmullius, Christiane

2013-04-01

Since the 1970s, radar remote sensing techniques have evolved rapidly and are increasingly employed in all fields of earth sciences. Applications are manifold and still expanding due to the continuous development of new instruments and missions as well as the availability of very high-quality data. The trend worldwide is towards operational employment of the various algorithms and methods that have been developed. However, the utilization of operational services does not keep up yet with the rate of technical developments and the improvements in sensor technology. With the enhancing availability and variety of space borne Synthetic Aperture Radar (SAR) data and a growing number of analysis algorithms the need for a vital user community is increasing. Therefore the German Aerospace Center (DLR) together with the Friedrich-Schiller-University Jena (FSU) and the Technical University Munich (TUM) launched the education initiative SAR-EDU. The aim of the project is to facilitate access to expert knowledge in the scientific field of radar remote sensing. Within this effort a web portal will be created to provide seminar material on SAR basics, methods and applications to support both, lecturers and students. The overall intension of the project SAR-EDU is to provide seminar material for higher education in radar remote sensing covering the topic holistically from the very basics to the most advanced methods and applications that are available. The principles of processing and interpreting SAR data are going to be taught using test data sets and open-source as well as commercial software packages. The material that is provided by SAR-EDU will be accessible at no charge from a DLR web portal. The educational tool will have a modular structure, consisting of separate modules that broach the issue of a particular topic. The aim of the implementation of SAR-EDU as application-oriented radar remote sensing educational tool is to advocate the development and wider use of

Assessing ambient ozone injury in olive (Olea europaea L.) plants by using the antioxidant ethylenediurea (EDU) in Saudi Arabia.

Science.gov (United States)

Basahi, J M; Ismail, I M; Haiba, N S; Hassan, I A; Lorenzini, G

2016-06-01

The antiozonant chemical, ethylenediurea (N-[2-(2-oxo-1-imidazolidinyl)ethyl]-N'-phenylurea, abbreviated as EDU), was applied as stem injections or soil drenches to 5-year-old containerized plants of olive (Olea europaea L. cultivar Kalamata) in growth chambers in order to assess its ameliorative effects against realistic ozone (O3) stress. Visible injury symptoms were reduced greatly in individuals treated with EDU, with injection applications having greater protection than soil drenches. EDU application caused increases in the measured ecophysiological parameters compared to untreated individuals. In particular, the stem injection protected plants against photosynthetic impairment (unchanged net photosynthetic rates and intercellular CO2 concentration, in comparison to plants grown in filtered air). EDU application increased the protection of PSII from ambient O3 oxidative stress, although it did not retain the proportion of redox state of QA, pigment composition of photosynthetic apparatus and size of light-harvesting complex of PSII. However, the stem injection of plants with EDU induced lower non-photochemical quenching (NPQ) values in comparison to ambient air (-2 %), indicating a better photoprotection of PSII in comparison to soil drench application. EDU application caused increases in the morphological and biometric parameters compared to individuals exposed to ambient air. To the best of our knowledge, this is the first study highlighting the protection of Kalamata olive trees due to EDU in terms of growth, yield, visible injury, and photosynthetic performance. Furthermore, this study proved that EDU could be a low-cost and a low-technology efficient tool for assessing O3 effects on plant performances in the field in Saudi Arabia.

Ethylenediurea (EDU): A research tool for assessment and verification of the effects of ground level ozone on plants under natural conditions

Energy Technology Data Exchange (ETDEWEB)

Manning, William J. [Department of Plant, Soil and Insect Sciences, University of Massachusetts, Amherst, MA 01003-9320 (United States); Paoletti, Elena, E-mail: e.paoletti@ipp.cnr.it [IPP CNR, Via Madonna del Piano 10, I-50019 Sesto Fiorentino (Italy); Sandermann, Heinrich [ecotox.freiburg, Schubertstr. 1, D-79104 Freiburg (Germany); Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Institute of Biochemical Plant Pathology, D-85764 Neuherberg (Germany); Ernst, Dieter [ecotox.freiburg, Schubertstr. 1, D-79104 Freiburg (Germany)

2011-12-15

Ethylenediurea (EDU) has been widely used to prevent ozone (O{sub 3}) injury and crop losses in crop plants and growth reductions in forest trees. Successful use requires establishing a dose/response curve for EDU and the proposed plant in the absence of O{sub 3} and in the presence of O{sub 3} before initiating multiple applications to prevent O{sub 3} injury. EDU can be used to verify foliar O{sub 3} symptoms in the field, and to screen plants for sensitivity to O{sub 3} under ambient conditions. Despite considerable research, the mode of action of EDU remains elusive. Additional research on the mode of action of EDU in suppressing O{sub 3} injury in plants may also be helpful in understanding the mode of action of O{sub 3} in causing injury in plants. - EDU is a verified and effective tool for the assessment of the effects of ozone on plants.

EduCTX: A blockchain-based higher education credit platform

OpenAIRE

Turkanović, Muhamed; Hölbl, Marko; Košič, Kristjan; Heričko, Marjan; Kamišalić, Aida

2017-01-01

Blockchain technology enables the creation of a decentralized environment where transactions and data are not under the control of any third party organization. Any transaction ever completed is recorded in a public ledger in a verifiable and permanent way. Based on blockchain technology, we propose a global higher education credit platform, named EduCTX. This platform is based on the concept of the European Credit Transfer and Accumulation System (ECTS). It constitutes a globally trusted, de...

High doses of ethylenediurea (EDU) as soil drenches did not increase leaf N content or cause phytotoxicity in willow grown in fertile soil.

Science.gov (United States)

Agathokleous, Evgenios; Paoletti, Elena; Manning, William J; Kitao, Mitsutoshi; Saitanis, Costas J; Koike, Takayoshi

2018-01-01

Ground-level ozone (O 3 ) levels are nowadays elevated in wide regions of the Earth, causing significant effects on plants that finally lead to suppressed productivity and yield losses. Ethylenediurea (EDU) is a chemical compound which is widely used in research projects as phytoprotectant against O 3 injury. The EDU mode of action remains still unclear, while there are indications that EDU may contribute to plants with nitrogen (N) when the soil is poor in N and the plants have relatively small leaf area. To reveal whether the N content of EDU acts as a fertilizer to plants when the soil is not poor in N and the plants have relatively large total plant leaf area, willow plants (Salix sachalinensis Fr. Schm) were exposed to low ambient O 3 levels and treated ten times (9-day interval) with 200mL soil drench containing 0, 800 or 1600mg EDU L -1 . Fertilizer was added to a nutrient-poor soil, and the plants had an average plant leaf area of 9.1m 2 at the beginning of EDU treatments. Indications for EDU-induced hormesis in maximum electron transport rate (J max ) and ratio of intercellular to ambient CO 2 concentration (C i :C a ) were observed at the end of the experiment. No other EDU-induced effects on leaf greenness and N content, maximum quantum yield of photosystem II (F v /F m ), gas exchange, growth and matter production suggest that EDU did not act as N fertilizer and did not cause toxicity under these experimental conditions. Copyright © 2017 Elsevier Inc. All rights reserved.

Solar UV-B effects on PSII performance in Betula nana are influenced by PAR level and reduced by EDU

DEFF Research Database (Denmark)

Albert, Kristian Rost; Mikkelsen, Teis Nørgaard; Ro-Poulsen, Helge

2012-01-01

-B transparent filter control (Teflon), UV-B-absorbing filter (Mylar) and UV-AB-absorbing filter (Lexan). Ethylenediurea (EDU), a chemical normally used to protect plants against ozone injury, was sprayed on the leaves both in the field and in an additional laboratory study to investigate if EDU mitigated...

Notes on inventive methodologies and affirmative critiques of an affective edu-future

DEFF Research Database (Denmark)

Staunæs, Dorthe

2016-01-01

of minds and bodies. Especially, motivation, engagement and the desire for learning are targets for policy and leadership technologies. This possible scenario is an affective edu-future that has connections to new modes of governance through standards and thereby present ways of leading educational...

Evaluation of the anti-oxidant ethylene diurea (EDU) as a protectant against ozone effects on crops (Growth chamber trials)

Energy Technology Data Exchange (ETDEWEB)

Archambault, D.J.; Li, X. [Alberta Research Council, Vegreville, AB (Canada). Environmental Technologies

2003-02-01

A field study conducted during the summer of 2000 showed that when the antioxidant ethylene diurea (EDU) was applied to crops there was an increase in several parameters. The authors designed a series of controlled-environment trials to test the following: were the effects of EDU the result of EDU-mediated protection against ozone (O{sub 3}) or were they from the plant growth promoting effects of EDU independent of O{sub 3}. The three major objectives were: (1) to modify an existing gas exposure system to expose plants to O{sub 3} and to test the stability and reliability of the system, (2) to perform O{sub 3} exposure trials using wheat, barley, field pea and canola to observe the effects of O{sub 3}, and (3) to test whether the effects of EDU could be attributed to protection against O{sub 3} injury or to the plant growth promoting effects independent of O{sub 3}. The modification to the gas exposure system involved the installation of an O{sub 3} delivery system and a monitoring system. Stability of the system was tested using radish plants. The symptoms of O{sub 3} injury on radish leaves began after two weeks of exposure. It appeared as mottled bleached areas which became red. Mottled chlorotic areas appeared on wheat and barley, which led to complete chlorosis, necrosis and eventually abscission. After two weeks of exposure, field pea developed tendril curl, and canola plants displayed no visible signs of injury from O{sub 3} exposure. The results of the study indicated that the effects of EDU can be species- and cultivar-specific. 15 refs., 11 tabs., 8 figs.

EduSIG: gvSIG aplicado a la enseñanza de la geografía

OpenAIRE

Bermejo Domínguez, Juan A.; Anguix Alfaro, Álvaro; Juncos, Raúl

2009-01-01

EduSIG parte de la idea de disponer de un SIG como herramienta educativa para el aprendizaje de la geografía. Por un lado EduSIG consiste en un gvSIG más simple, sin herramientas complejas o muy técnicas, que permite navegar, consultar, construir y entender los mapas sin necesitar ninguna formación en Sistemas de Información Geográfica. Por otro lado pretende dar una visión didáctica de la enseñanza de la geografía, incluyendo tanto vistas temáticas predefinidas y diverso...

MO-DE-BRA-03: TOPAS-edu: A Window Into the Stochastic World Through the TOPAS Tool for Particle Simulation

International Nuclear Information System (INIS)

Perl, J; Villagomez-Bernabe, B; Currell, F

2015-01-01

Purpose: The stochastic nature of the subatomic world presents a challenge for physics education. Even experienced physicists can be amazed at the varied behavior of electrons, x-rays, protons, neutrons, ions and the any short-lived particles that make up the overall behavior of our accelerators, brachytherapy sources and medical imaging systems. The all-particle Monte Carlo particle transport tool, TOPAS Tool for Particle Simulation, originally developed for proton therapy research, has been repurposed into a physics teaching tool, TOPAS-edu. Methods: TOPAS-edu students set up simulated particle sources, collimators, scatterers, imagers and scoring setups by writing simple ASCII files (in the TOPAS Parameter Control System format). Students visualize geometry setups and particle trajectories in a variety of modes from OpenGL graphics to VRML 3D viewers to gif and PostScript image files. Results written to simple comma separated values files are imported by the student into their preferred data analysis tool. Students can vary random seeds or adjust parameters of physics processes to better understand the stochastic nature of subatomic physics. Results: TOPAS-edu has been successfully deployed as the centerpiece of a physics course for master’s students at Queen’s University Belfast. Tutorials developed there takes students through a step by step course on the basics of particle transport and interaction, scattering, Bremsstrahlung, etc. At each step in the course, students build simulated experimental setups and then analyze the simulated results. Lessons build one upon another so that a student might end up with a full simulation of a medical accelerator, a water-phantom or an imager. Conclusion: TOPAS-edu was well received by students. A second application of TOPAS-edu is currently in development at Zurich University of Applied Sciences, Switzerland. It is our eventual goal to make TOPAS-edu available free of charge to any non-profit organization, along with

MO-DE-BRA-03: TOPAS-edu: A Window Into the Stochastic World Through the TOPAS Tool for Particle Simulation

Energy Technology Data Exchange (ETDEWEB)

Perl, J [Stanford Linear Accelerator Center, Menlo Park, CA (United States); Villagomez-Bernabe, B; Currell, F [Queen’s University Belfast, Belfast, Northern Ireland (United Kingdom)

2015-06-15

Purpose: The stochastic nature of the subatomic world presents a challenge for physics education. Even experienced physicists can be amazed at the varied behavior of electrons, x-rays, protons, neutrons, ions and the any short-lived particles that make up the overall behavior of our accelerators, brachytherapy sources and medical imaging systems. The all-particle Monte Carlo particle transport tool, TOPAS Tool for Particle Simulation, originally developed for proton therapy research, has been repurposed into a physics teaching tool, TOPAS-edu. Methods: TOPAS-edu students set up simulated particle sources, collimators, scatterers, imagers and scoring setups by writing simple ASCII files (in the TOPAS Parameter Control System format). Students visualize geometry setups and particle trajectories in a variety of modes from OpenGL graphics to VRML 3D viewers to gif and PostScript image files. Results written to simple comma separated values files are imported by the student into their preferred data analysis tool. Students can vary random seeds or adjust parameters of physics processes to better understand the stochastic nature of subatomic physics. Results: TOPAS-edu has been successfully deployed as the centerpiece of a physics course for master’s students at Queen’s University Belfast. Tutorials developed there takes students through a step by step course on the basics of particle transport and interaction, scattering, Bremsstrahlung, etc. At each step in the course, students build simulated experimental setups and then analyze the simulated results. Lessons build one upon another so that a student might end up with a full simulation of a medical accelerator, a water-phantom or an imager. Conclusion: TOPAS-edu was well received by students. A second application of TOPAS-edu is currently in development at Zurich University of Applied Sciences, Switzerland. It is our eventual goal to make TOPAS-edu available free of charge to any non-profit organization, along with

Factors affecting the effects of EDU on growth and yield of field-grown bush beans (Phaseolus vulgaris L.), with varying degrees of sensitivity to ozone

Energy Technology Data Exchange (ETDEWEB)

Elagoez, Vahram [Plant Biology Graduate Program, University of Massachusetts, Amherst, MA 01003 (United States)]. E-mail: velagoz@nsm.umass.edu; Manning, William J. [Department of Plant, Soil and Insect Sciences, University of Massachusetts, Amherst, MA 01003 (United States)

2005-08-15

The effects of foliar applications of ethylenediurea (EDU) on responses to ozone by field-grown bush bean (Phaseolus vulgaris L.) lines 'S156' (O{sub 3}-sensitive) and 'R123' (O{sub 3}-tolerant), and cultivars 'BBL 290' (O{sub 3}-sensitive) and 'BBL 274' (O{sub 3}-tolerant) were investigated during the 2001 and 2002 growing seasons. EDU was applied weekly to designated plants between primary leaf expansion and pod senescence. Results were compared with control plants at harvests made at pod maturation and pod senescence. In 2001, average hourly ambient O{sub 3} concentrations ranged between 41 and 59 ppb for a total of 303 h; in 2002, for 355 h. EDU applications prior to pod maturation significantly increased the number of marketable pods in 'R123', but not for the other cultivars. Harvests at pod senescence showed significant improvements in crop yield production in EDU-treated 'S156' plants, whereas for EDU-treated 'R123' plants significant reductions were determined in above-ground biomass and seed production. In contrast, results from 'BBL 290' and 'BBL 274' at both harvest points were inconclusive. Growth and reproductive responses of O{sub 3}-sensitive and O{sub 3}-tolerant bush bean plants to EDU applications varied, depending on developmental stages, duration of EDU applications, and fluctuations in ambient O{sub 3}. - Plant sensitivity to ozone, stage of plant development, number of applications of EDU and ambient ozone affect bean plant responses to EDU.

Protection of ash (Fraxinus excelsior) trees from ozone injury by ethylenediurea (EDU): Roles of biochemical changes and decreased stomatal conductance in enhancement of growth

International Nuclear Information System (INIS)

Paoletti, Elena; Contran, Nicla; Manning, William J.; Castagna, Antonella; Ranieri, Annamaria; Tagliaferro, Francesco

2008-01-01

Treatments with ethylenediurea (EDU) protect plants from ozone foliar injury, but the processes underlying this protection are poorly understood. Adult ash trees (Fraxinus excelsior), with or without foliar ozone symptoms in previous years, were treated with EDU at 450 ppm by gravitational trunk infusion in May-September 2005 (32.5 ppm h AOT40). At 30-day intervals, shoot growth, gas exchange, chlorophyll a fluorescence, and water potential were determined. In September, several biochemical parameters were measured. The protective influence of EDU was supported by enhancement in the number of leaflets. EDU did not contribute its nitrogen to leaf tissue as a fertiliser, as determined from lack of difference in foliar N between treatments. Both biochemical (increase in ascorbate-peroxidase and ascorbic acid, and decrease in apoplastic hydrogen peroxide) and biophysical (decrease in stomatal conductance) processes regulated EDU action. As total ascorbic acid increased only in the asymptomatic trees, its role in alleviating O 3 effects on leaf growth and visible injury is controversial. - Both biochemical and biophysical processes may regulate EDU action

The Communicative Ability of Universiti Teknologi MARA Sarawak's Graduates

Science.gov (United States)

Hassan, Sharifah Zakiah Wan; Hakim, Simon Faizal; Rahim, Mahdalela; Noyem, John Francis; Ibrahim, Sueb; Ahmad, Johnny; Jusoff, Kamaruzaman

2009-01-01

This study explores Universiti Teknologi MARA (UiTM) Sarawak graduating students' oral proficiency, focusing on grammatical accuracy. Oral proficiency in English has always been the benchmark of language proficiency, and in the context of UiTM's language teaching curriculum, efforts to enhance students' oral proficiency are implemented through…

Hiring, Social Media, and E-Due Diligence

Science.gov (United States)

Wodarz, Nan

2011-01-01

Social networking sites are those Websites that allow for a variety of social interactions with friends and family. Literally hundreds of social sites exist, but those most frequently used are Facebook, MySpace, Twitter, and Linkedln. These sites are most commonly used by 20-somethings to folks in their mid-40s. In this article, the author…

Organisatsiooni ja juhtimise valdkonna paradigma ja selle muutumine sõltuvalt edu-uskumusest / Heinrich Ausmees

Index Scriptorium Estoniae

Ausmees, Heinrich, 1941-

2004-01-01

Autori väitel uus edu-uskumus eeldab, et kui me oleme suutelised looma metafoore toimuvatest protsessidest, siis oleme võimelised, või vähemalt oleme loonud eeldused selleks, et valdkonnas tegutseda ja muutusi esile kutsuda

New tools for scientific learning in the EduSeis project: the e-learning experiment

Directory of Open Access Journals (Sweden)

A. Zollo

2007-06-01

Full Text Available The Educational Seismological Project (EduSeis is a scientific and educational project, the main aim of which is the development and implementation of new teaching methodologies in Earth Sciences, using seismology as a vehicle for scientific learning and awareness of earthquake risk. Within this framework, we have recently been experimenting with new learning and information approaches that are mainly aimed at a high school audience. In particular, we have designed, implemented and tested a model of an e-learning environment in a high school located in the surroundings of the Mt. Vesuvius volcano. The proposed e-learning model is built on the EduSeis concepts and educational materials (web-oriented, and is based on computer-supported collaborative learning. Ten teachers from different disciplines and fifty students at the I.T.I.S. “Majorana” technical high school (Naples have been taking part in a cooperative e-learning experiment in which the students have been working in small groups (communities. The learning process is assisted and supervised by the teachers. The evaluation of the results from this cooperative e-learning experiment has provided useful insights into the content and didactic value of the EduSeis modules and activities. The use of network utilities and the “Learning Community” approach promoted the exchange of ideas and expertises between students and teachers and allowed a new approach to the seismology teaching through a multidisciplinary study.

IDES-EDU – new interdisciplinary education program for Sustainable Buildings

DEFF Research Database (Denmark)

Dvorakova, Pavla; Kabele, Karel; Brunsgaard, Camilla

2013-01-01

Buildings fulfilling all requirements related to energy, economy and environment are necessary to be designed by interdisciplinary teams with efficient transfer of information and good knowledge base. IDES EDU is a project co-funded by the Intelligent Energy Europe program in which 15 European...... universities make a concerted effort to develop and implement balanced master and postgraduate courses on Sustainable Energy Design providing skills and knowledge that exceed the requirements of the EPBD. The resulting courses focus on different aspects of sustainable building design from the perspective...

My Secret Life.

Science.gov (United States)

Chilton, Mary-Dell

2018-04-29

In my early childhood, my parents gave me to my maternal grandparents for a "visit" that extended over a period of nine years. I seemed to be a fairly ordinary student in primary grades, and had to take a remedial general science class upon entering high school, my first exposure to science. It was the teacher of that class, Mr. Auer, who told me that I had scored amazingly high on a science aptitude test given to all freshmen. The people who administered the testing were convinced that I must have cheated somehow. Mr. Auer suggested that I might want to consider a career in science if I liked it. I loved it, and I did. This autobiographical article recounts my changing interests as I became aware of new fields of science during my education and the start of my career. Out of basic studies of a microbe that causes plant cancer, we developed a method to engineer new and useful genes into crop plants.

mySearch changed my life – a resource discovery journey

OpenAIRE

Crowley, Emma J.

2013-01-01

mySearch: the federated years mySearch: choosing a new platform mySearch: EBSCO Discovery Service (EDS) Implementing a new system Technical challenges Has resource discovery enhanced experiences at BU? Ongoing challenges Implications for library management systems Implications for information literacy Questions

Kesklinna kolimine tõi Renault' müüjale loodetust suurema edu / Tõnu Tramm

Index Scriptorium Estoniae

Tramm, Tõnu, 1968-

2005-01-01

TOP-i 2. koht. Renault'sid müüva Autori AS-i juht Vello Tamm peab ettevõtte edu aluseks kolimist kesklinna ning senise töö analüüsimist ja uute eesmärkide seadmist. Diagramm: Majandusnäitajad

Assessing effects of ambient ozone on injury and growth of Trifolium subterraneum at four rural sites in the Netherlands with ethylenediurea (EDU)

NARCIS (Netherlands)

Tonneijck, A.E.G.; Dijk, van C.J.

1997-01-01

To assess adverse effects of ambient ozone on injury and growth, EDU (ethylenediurea) and non-EDU-treated plants of subterranean clover (Trifolium subterraneum cv. Geraldton) were exposed to ambient air at four rural sites in the Netherlands. In each of two successive experiments of eight weeks

Exploring Application, Attitudes and Integration of Video Games: MinecraftEdu in Middle School

Science.gov (United States)

Sáez-López, José-Manuel; Miller, John; Vázquez-Cano, Esteban; Domínguez-Garrido, María-Concepción

2015-01-01

The aim of this study is to assess the use of MinecraftEdu in classroom practice analyzing the outcomes and attitudes of all members of the educational community through a quasi-experimental approach. The research presents three dimensions oriented to assessing the use of this application in a didactic unit "History and Architecture"…

screening for cognitive impairment in late onset depression in a Brazilian sample using the BBRC-edu

Directory of Open Access Journals (Sweden)

Tânia Maria da Silva Novaretti

Full Text Available ABSTRACT Depression and dementia are the most prevalent neuropsychiatric disorders in the elderly population. Alzheimer's disease is the leading cause of dementia in most countries, being responsible for more than half of all dementia cases. Late-onset depression is a frequent cause of cognitive decline in the elderly. Differentiating between cognitive impairment secondary to depression and incipient dementia poses a challenge in the clinical setting. Objective: To evaluate the performance of elderly depressed patients using the BBRC-Edu. Methods: We studied 25 patients with late onset depression (mean age: 73.6 y (6.6; schooling: 9.1 y (5.7 and 30 patients with mild AD (mean age 76.6 y (5.4; schooling: 7.5 y (7.1, who were compared to a control group of 30 healthy elderly (mean age 73.8 y (5.8; schooling: 9.1 y (5.4 using the CERAD and BBRC-Edu batteries. Results: For the CERAD battery, depressed patients performed better than AD patients on all tasks (p0.05, and performed poorer than controls on verbal fluency (animals and Word List Recall tasks (p0.05, and performed worse than controls on Learning (second presentation and verbal fluency (fruits tasks (p<0.0001. Conclusion: Overall performance on the BBRC-Edu allowed differentiation of controls and depressed patients from AD patients.

The first toxicological study of the antiozonant and research tool ethylene diurea (EDU) using a Lemna minor L. bioassay: Hints to its mode of action

International Nuclear Information System (INIS)

Agathokleous, Eugenios; Mouzaki-Paxinou, Akrivi-Chara; Saitanis, Costas J.; Paoletti, Elena; Manning, William J.

2016-01-01

The antiozonant and research tool ethylene diurea (EDU) is widely studied as a phytoprotectant against the widespread pollutant ground-surface ozone. Although it has been extensively used, its potential toxicity in the absence of ozone is unknown and its mode of action is unclear. The purpose of this research was to toxicologically assess EDU and to further investigate its mode of action using Lemna minor L. as a model organism. Application of EDU concentrations greater than 593 mg L −1 (practically 600 mg L −1 ) resulted in adverse inhibition of colony growth. As no-observed-toxic-effects concentration (NOEL) we recommend a concentration of 296 mg L −1 (practically 300 mg L −1 ). A hormetic response was detected, i.e. stimulatory effects of low EDU concentrations, which may indicate overcompensation in response to disruption in homeostasis. Growth inhibition and suppressed biomass were associated with impacted chlorophyll a fluorescence (Φ PSII , q P and ETR). Furthermore, EDU increased mesophyll thickness, as indicated by frond succulence index. Applications of concentrations ≥593 mg L −1 to uncontrolled environments should be avoided due to potential toxicity to sensitive organisms and the environment. - Highlights: • The EDU concentration of 300 mg L −1 should be considered as NOEL. • EDU concentrations ≥600 mg L −1 should not be applied to uncontrolled environments. • Hormetic responses indicate overcompensation in response to homeostasis disruption. - Ethylene diurea is not toxic to sensitive organisms when applied at low concentrations (practically < 600 mg L −1 ).

myCOFFEE & myBAR:n ydinsegmentin kartoitus ja tuottavuus

OpenAIRE

Rautiainen, Hanne; Kaihola, Jenni

2009-01-01

Opinnäytetyön tarkoituksena oli saada selville myCOFFEE & myBAR:n tuottavin asiakassegmentti tai segmentit. Lisäksi opinnäytetyössä selvitettiin, kuinka asiakkaat muuten kokevat yrityksen palvelun sekä tutkitaan asiakas- ja ostokäyttäytymistä. Työssä selvitettiin myös mahdollisia kehittämiskohteita sekä poh-ditaan, kuinka yritys voisi saada lisää potentiaalisia asiakkaita. Asiakaspalvelu on yksi markkinoinnin tärkeimmistä kilpailukeinoista. Sillä voidaan erottua kilpailijoista, ja nykyis...

Learning MySQL

CERN Document Server

Tahaghoghi, Saied M M

2007-01-01

Whether you're running a business, keeping track of members andmeetings for a club, or just trying to organize a large and diversecollection of information, you'll find the MySQL database engineuseful for answering questions such as: Which are my top ten fastest-selling products?How frequently does this person come to our facility?What was the highest, lowest, and average score of the team last season? MySQL, the most popular open-source database, offers the power ofa relational database in a package that's easy to set up andadminister, and Learning MySQL provides all the tools you need to

Expansion of the HMX-1 Flight Envelope With the EDU-5/P Laser Eye Protection Spectacles

National Research Council Canada - National Science Library

Penhallegon, William

2004-01-01

...) takeoffs and landings. Flight testing determined that fit, internal and external lighting conditions, aircrew experience, and aircrafi type are important factors in determining the suitability of the EDU-iIP in HMX-I plafforms...

How Have I Come to Recognise and Develop My Talents Which Are My Gift to My Colleagues and Pupils

Science.gov (United States)

Kemp, Kate

2016-01-01

Using a Living Theory approach to action research I explore "Gifts, Talents and Education" by considering what my "unique talent" is, and I use my response as a lens through which to examine literature on the subject and my own professional and personal experience. I have used narratives, written over time, as data to which I…

The Affections of My Life

Institute of Scientific and Technical Information of China (English)

Zhang; Yan; Shi; Xiao; jing

2013-01-01

<正>When I look back over the 90 years of my life, through all the tumultuous events, highs and lows, joys and sorrows, I see that one bright, shining emotion has always warmed my heart: affection. The pillar supporting me throughout has been family love: the care of my parents, the love of my wife and children, and the close feelings between myself and my

The first toxicological study of the antiozonant and research tool ethylene diurea (EDU) using a Lemna minor L. bioassay: Hints to its mode of action.

Science.gov (United States)

Agathokleous, Eugenios; Mouzaki-Paxinou, Akrivi-Chara; Saitanis, Costas J; Paoletti, Elena; Manning, William J

2016-06-01

The antiozonant and research tool ethylene diurea (EDU) is widely studied as a phytoprotectant against the widespread pollutant ground-surface ozone. Although it has been extensively used, its potential toxicity in the absence of ozone is unknown and its mode of action is unclear. The purpose of this research was to toxicologically assess EDU and to further investigate its mode of action using Lemna minor L. as a model organism. Application of EDU concentrations greater than 593 mg L(-1) (practically 600 mg L(-1)) resulted in adverse inhibition of colony growth. As no-observed-toxic-effects concentration (NOEL) we recommend a concentration of 296 mg L(-1) (practically 300 mg L(-1)). A hormetic response was detected, i.e. stimulatory effects of low EDU concentrations, which may indicate overcompensation in response to disruption in homeostasis. Growth inhibition and suppressed biomass were associated with impacted chlorophyll a fluorescence (ΦPSII, qP and ETR). Furthermore, EDU increased mesophyll thickness, as indicated by frond succulence index. Applications of concentrations ≥593 mg L(-1) to uncontrolled environments should be avoided due to potential toxicity to sensitive organisms and the environment. Copyright © 2016 Elsevier Ltd. All rights reserved.

My Nepalese Friends

Institute of Scientific and Technical Information of China (English)

1996-01-01

NEPAL and China are good neighbors. In the 1980s many Chinese technicians went to Nepal to help build roads and other projects. As an interpreter with a Chinese construction cooperative, I worked there from 1993 to 1994. During my stay in Nepal, I met many different Nepalese women who impressed me deeply. My landlady Sumiyala, was the first Nepalese woman to come into my life. She was over 40 years old, a healthy and good-humored housewife. Whenever Ⅰ had time, I liked to chat with her and gradually we became friends. I remember my landlady was busy in and out of her house all day long— cleaning, cooking and taking care of her grandchildren and her parents-in-laws.

Mastering phpMyAdmin 34 for Effective MySQL Management

CERN Document Server

Delisle, Marc

2012-01-01

This is a step-by-step instructional guide to get you started easily with phpMyAdmin and teach you to manage and perform database functions on your database. You will first be introduced to the interface and then build basic tables and perform both simple and advanced functions on the created database. The book progresses gradually and you will follow it best by reading it sequentially. If you are a developer, system administrator, or web designer who wants to manage MySQL databases and tables efficiently, then this book is for you. This book assumes that you are already wellacquainted with My

Perception determinants in learning mathematics

Science.gov (United States)

Mokhtar, Siti Fairus; Ali, Noor Rasidah; Rashid, Nurazlina Abdul

2015-05-01

This article described a statistical study of students' perception in mathematics. The objective of this study is to identify factors related to perception about learning mathematics among non mathematics' student. This study also determined the relationship between of these factors among non mathematics' student. 43 items questionnaires were distributed to one hundred students in UiTM Kedah who enrolled in the Business Mathematics course. These items were measured by using a semantic scale with the following anchors: 1 = strongly disagree to 7 = strongly agree. A factor analysis of respondents were identified into five factors that influencing the students' perception in mathematics. In my study, factors identified were attitude, interest, role of the teacher, role of peers and usefulness of mathematics that may relate to the perception about learning mathematics among non mathematics' student.

Beginning MySQL

CERN Document Server

Sheldon, Robert

2005-01-01

Provides programmers with a complete foundation in MySQL, the multi-user, multi-threaded SQL database server that easily stores, updates, and accesses informationOffers detailed instructions for MySQL installation and configuration on either Windows or LinuxShows how to create a database, work with SQL, add and modify data, run queries, perform administrative tasks, and build database applicationsDemonstrates how to connect to a MySQL database from within PHP, Java, ASP, and ASP.NET applicationsCompanion Web site includes SQL statements needed to create and populate a database plus three ready

Why Did My Doctor Prescribe Birth Control Pills for My Acne?

Science.gov (United States)

... Health Food & Fitness Diseases & Conditions Infections Drugs & Alcohol School & Jobs Sports Expert Answers (Q&A) Staying Safe Videos for Educators Search English Español Why Did My Doctor Prescribe Birth Control Pills for My Acne? KidsHealth / For Teens / Why ...

31 CFR 370.7 - How can my financial institution change my designated deposit account?

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false How can my financial institution... Entries § 370.7 How can my financial institution change my designated deposit account? If your financial.... The financial institution's request will be deemed an agreement by the institution to indemnify us and...

4th International Conference on Electronic Devices, Systems and Applications 2015 (ICEDSA)

Science.gov (United States)

Herman, Sukreen Hana

2015-11-01

On behalf of the Organizing Committee of ICEDSA2015, and with great pleasure, we would like to welcome all delegates to Kuala Lumpur, Malaysia. Being held from 14th to 15th September 2015 at Hotel Istana, Kuala Lumpur, the event is co-sponsored by the Faculty of Electrical Engineering, Universiti Teknologi MARA (UiTM), Malaysia, and the American University of Ras Al Khaimah, (AURAK), United Arab Emirates. This joint conference is an event held under the MoU signed between UiTM and AURAK, the aim being for this conference to be organized by both universities in the future. The conference creates a forum for engineers, scientists and practitioners of varied disciplines and their associated applications. Throughout this event we hope to create an opportunity for researchers, academics and students to get together and, more importantly, to welcome new peers in diverse areas of expertise. On behalf of the organizing committee we would like to take the opportunity to express our gratitude to all reviewers who have been working hard to review the papers on time and share their expertise. Special mention goes to the distinguished Keynote Speakers for their willingness to spend their time and share their valuable knowledge. My deepest gratitude goes to the Organizing Committee who have been working hard behind the scenes for the success of this event. To all participants, we would like to encourage you to fully utilize this platform for knowledge sharing and networking while enjoying your stay in Kuala Lumpur.

EPICS MySQL Archiver - integration between EPICS and MySQL

International Nuclear Information System (INIS)

Roy, A.; Bhole, R.B.; Pal, S.; Sarkar, D.

2012-01-01

The performance evaluation and analysis of intersystem dependency of the various subsystems of the Superconducting Cyclotron (SCC) demand a well configured data logging, archiving and historic analysis facility for large number of control parameters along with on-line failure analysis facility of every system. Experimental Physics and Industrial Control System (EPICS) is used as development architecture of the control system of these systems with MySQL as database for large amount of relational data management. This combination requires integration between EPICS and MySQL server. For this purpose, MySQL Archiver as an EPICS Extension is developed for data logging and archiving of control parameters into MySQL database. This extension also provides a web based tool for online monitoring of control parameters and historic analysis of archived data. This paper describes the software architecture, implementation, as well as method of configuration for any other EPICS based control system as a utility. This facility is also elaborated with examples, web page views and experiences of deploying it in SCC. (author)

This is My Family

OpenAIRE

Yeğen, Hale Nur; Çetin, Merve

2017-01-01

Me and my family, Families poem, Mother-Father, Brother-Sister, Grandparents, Uncle-Aunt, Cousin, Family, Family handgame, My family tree, Activities (Three In a Family), Digital Games, A family poem, Quiz

My winding trail while fulfilling my love for science and family.

Science.gov (United States)

Orth, Kim

2018-04-11

My winding path toward a career in science was awkward, like an adolescent finding an identity. It did not follow a classic course; it had many interruptions, complications, and challenges. It also involved a bit of luck and extremely supportive colleagues, mentors, and family, including my husband, children, and in-laws. I was inspired to tell my story here because I met a young woman interviewing in 2018 for graduate school who is growing up with the same complicated family expectations, social challenges, love for science, and desire to be a scientist as I had four decades ago. Her future is uncertain, because her chosen academic path is not encouraged by those around her. We, as a society, must find ways to encourage, promote, enable, and give strength to those who want to follow their dreams despite facing many challenges in their lives. Here are some things I learned on my career path that I hope might be helpful for others. Published under license by The American Society for Biochemistry and Molecular Biology, Inc.

玩转My Phone

Institute of Scientific and Technical Information of China (English)

树子

2009-01-01

2009年3月，微软同步服务My Phone开始对Windows Live Messenger用户开放试用。相比之前推出的Google Sync同步服务，My Phone的适用范围虽然较窄，只能支持Windows Mobile 6．0以上的智能手机操作系统。但是，My Phone所提供的功能比Google Sync更让人期待。

Pushing Boundaries: My Personal and Scientific Journey

Science.gov (United States)

Sarachik, Myriam P.

2018-03-01

This autobiographical narrative offers a brief account of my journey and adventures in condensed matter physics (a.k.a. solid state physics) and some of the personal events that shaped my life and my career: my early years in Europe, my family's escape from the Nazis, growing up in Cuba, the difficult road into a field that was essentially closed to women, a personal disaster that knocked the wind out of my sails for more than a decade, and my return to a successful career in physics. In closing, I argue that, although we have made remarkable progress, we know but a thimble-full in our inexhaustible search for an understanding of the laws of nature.

MyPlate Food Guide

Science.gov (United States)

... Safe Videos for Educators Search English Español MyPlate Food Guide KidsHealth / For Teens / MyPlate Food Guide What's ... and other sugary drinks. Avoid large portions . Five Food Groups Different food groups have different nutrients and ...

Effects of long-term ambient ozone exposure on biomass and wood traits in poplar treated with ethylenediurea (EDU)

International Nuclear Information System (INIS)

Carriero, G.; Emiliani, G.; Giovannelli, A.; Hoshika, Y.; Manning, W.J.; Traversi, M.L.; Paoletti, E.

2015-01-01

This is the longest continuous experiment where ethylenediurea (EDU) was used to protect plants from ozone (O 3 ). Effects of long-term ambient O 3 exposure (23 ppm h AOT40) on biomass of an O 3 sensitive poplar clone (Oxford) were examined after six years from in-ground planting. Trees were irrigated with either water or 450 ppm EDU. Above (−51%) and below-ground biomass (−47%) was reduced by O 3 although the effect was significant only for stem and coarse roots. Ambient O 3 decreased diameter of the lower stem, and increased moisture content along the stem of not-protected plants (+16%). No other change in the physical wood structure was observed. A comparison with a previous assessment in the same experiment suggested that O 3 effects on biomass partitioning to above-ground organs depend on the tree ontogenetic stage. The root/shoot ratios did not change, suggesting that previous short-term observations of reduced allocation to tree roots may be overestimated. - Highlights: • 6-y ambient O 3 exposure was investigated in a sensitive poplar clone. • EDU irrigation protected poplar against ambient O 3 exposure. • O 3 reduced biomass of roots and stem, but did not change biomass allocation. • O 3 decreased stem diameter only in the lower third of the stem. • O 3 increased moisture content of the wood along the stem. - Ozone exposure reduced lateral branching, leaves and roots in younger trees, and affected stem and roots in older trees, while shoot/root ratios did not change.

Managing and Using MySQL

CERN Document Server

Reese, George; King, Tim

2002-01-01

MySQL is a popular and robust open source database product that supports key subsets of SQL on both Linux and Unix systems. MySQL is free for nonprofit use and costs a small amount for commercial use. Unlike commercial databases, MySQL is affordable and easy to use. This book includes introductions to SQL and to relational database theory. If you plan to use MySQL to build web sites or other Linux or Unix applications, this book teaches you to do that, and it will remain useful as a reference once you understand the basics. Ample tutorial material and examples are included throughout.

Employing Microsoft Live@edu Cloud Platform to Assist in Teaching Chinese Reading for Junior High School Students

Science.gov (United States)

Shih, Ru-Chu; Cho, Chia-Liang; Tsai, Chih-Cheng; Lou, Shi-Jer

2013-01-01

This study aimed to investigate junior high school students' learning attitudes and learning effectiveness through administering Microsoft Live@edu to assist in teaching Chinese reading. Quasi-experimental approach was used and a total of 63 eighth grade students were divided into the experimental group (N = 32) and control group (N = 31).…

Encouraging girl child education in my village

Directory of Open Access Journals (Sweden)

Delphine Entongwe

2015-03-01

Full Text Available My critical reflection will be drawn from an experience I had just a year after my graduation from the university where I was appointed as one of the X-students to lead a student cultural week in my village with the theme “raising awareness on education”. At the university, I was a member of my association in which students from my tribe generally come together to promote unity and encourage others in education. My role was to present a discourse on girl child education all the entire villagers who were gathered at the village square that evening. A high dropout rate at school and illiteracy are major problems in my region, in which there is still a great deal of gender disparity when it comes to educating children, especially the girl child. This programme is in line with the government’s policy of promoting education in my country, whose priority is for education to reach the grass-roots communities.

My experience with research

Indian Academy of Sciences (India)

Lawrence

my heart that scientific research was my true calling. The Head of the ... This was a new area to explore in Physics, and I was initi- ated into this field at the ... physicists in Guwahati had no idea about a Plasma Physics Labo- ratory! Our theory ...

Reconstruction of Orion Engineering Development Unit (EDU) Parachute Inflation Loads

Science.gov (United States)

Ray, Eric S.

2013-01-01

The process of reconstructing inflation loads of Capsule Parachute Assembly System (CPAS) has been updated as the program transitioned to testing Engineering Development Unit (EDU) hardware. The equations used to reduce the test data have been re-derived based on the same physical assumptions made by simulations. Due to instrumentation challenges, individual parachute loads are determined from complementary accelerometer and load cell measurements. Cluster inflations are now simulated by modeling each parachute individually to better represent different inflation times and non-synchronous disreefing. The reconstruction procedure is tailored to either infinite mass or finite mass events based on measurable characteristics from the test data. Inflation parameters are determined from an automated optimization routine to reduce subjectivity. Infinite mass inflation parameters have been re-defined to avoid unrealistic interactions in Monte Carlo simulations. Sample cases demonstrate how best-fit inflation parameters are used to generate simulated drag areas and loads which favorably agree with test data.

How Do I Talk to My Family about Gaucher?

Science.gov (United States)

... to my parents and the rest of our family. My father and mother did not want to accept the ... holding fundraisers and speaking to Jewish organizations. My family also got tested: My father had asymptomatic Gaucher, my mother is a carrier, ...

Can the Weather Affect My Child's Asthma?

Science.gov (United States)

... English Español Can the Weather Affect My Child's Asthma? KidsHealth / For Parents / Can the Weather Affect My ... Asthma? Print Can the Weather Affect My Child's Asthma? Yes. Weather conditions can bring on asthma symptoms. ...

My career in medical research

Indian Academy of Sciences (India)

Lawrence

Sitaramayya, who taught Sir C.V. Raman during his school days. My earliest ... responsible for this condition, changes in other organs, biochemi- cal parameters and ... My work was published in a number of international journals of repute,.

41 CFR 302-15.13 - What are the income tax consequences when my agency pays for my property management services?

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What are the income tax consequences when my agency pays for my property management services? 302-15.13 Section 302-15.13 Public....13 What are the income tax consequences when my agency pays for my property management services? When...

40 CFR 141.564 - My system practices lime softening-is there any special provision regarding my individual filter...

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 22 2010-07-01 2010-07-01 false My system practices lime softening-is... People Individual Filter Turbidity Requirements § 141.564 My system practices lime softening—is there any special provision regarding my individual filter turbidity monitoring? If your system utilizes lime...

40 CFR 141.553 - My system practices lime softening-is there any special provision regarding my combined filter...

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 22 2010-07-01 2010-07-01 false My system practices lime softening-is... Filter Effluent Requirements § 141.553 My system practices lime softening—is there any special provision regarding my combined filter effluent? If your system practices lime softening, you may acidify...

How the Internet Saved My Daughter and How Social Media Saved My Family

Science.gov (United States)

Santos, Marc C.

2011-01-01

This installation is a personal and cathartic engagement with my initial inability to cope with my daughter's cancer. It details events that began in August of 2008 and concluded, in a sense, in February of 2009. I offer it with hopes of helping digitally-oriented rhetoric and composition scholars "determin[e] a should for a we" (Patricia Sullivan…

Head first PHP and MySQL

CERN Document Server

Beighley, Lynn

2008-01-01

If you're ready to create web pages more complex than those you can build with HTML and CSS, Head First PHP & MySQL is the ultimate learning guide to building dynamic, database-driven websites using PHP and MySQL. Packed with real-world examples, this book teaches you all the essentials of server-side programming, from the fundamentals of PHP and MySQL coding to advanced topics such as form validation, session IDs, cookies, database queries and joins, file I/O operations, content management, and more. Head First PHP & MySQL offers the same visually rich format that's turned every title in th

MyPlate: Build a Healthy Eating Style

Science.gov (United States)

... help others in their journey to make healthy eating a part of their lives. What Is MyPlate? Food Guide History MyPlate, MyWins Fruits All About the Fruit Group Nutrients and Health Benefits TIPS: Focus on Whole Fruits Food Gallery Take ...

Edu Lobo e Carlos Lyra: O Nacional e o Popular na Canção de Protesto (Os Anos 60

Directory of Open Access Journals (Sweden)

Arnaldo Daraya Contier

1998-01-01

Full Text Available Trata-se de um estudo sobre as possíveis conexões entre a canção de protesto (Edu Lobo, Carlos Lyra e os discursos do CPC durante os anos 60. As criações artísticas são analisadas com vistas a captar os vínculos entre o nacional-popular na canção brasileira e o impressionismo (C. Debussy, o cool-jazz (Miles Davis, Rodgers and Hart, Heitor Villa-Lobos (modernismo, Waldemar Henrique.This is a study if the possible connections between the protest song (Edu Lobo, Carlos Lyra and the CPC discourses in the 1960s. The artistics creations are analysed with a view to pointing out the ties between the national-popular in Brazilian song and the impressionism (C. Debussy, the cool-jazz (Miles Davis, Rodgers and Hart, Heitor Villa-Lobos (modernism, Waldemar Henrique.

41 CFR 301-13.2 - Under what conditions will my agency pay for my additional travel expense(s) under this part?

Science.gov (United States)

2010-07-01

... will my agency pay for my additional travel expense(s) under this part? 301-13.2 Section 301-13.2 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL... conditions will my agency pay for my additional travel expense(s) under this part? When an additional travel...

My Son 22.10.11

Directory of Open Access Journals (Sweden)

Rebecca Baillie

2013-01-01

Full Text Available 'My Son 22.10.11' was made immediately following a miscarriage 8 weeks into pregnancy. After bleeding lightly for a couple of hours, I went to the toilet and a large bloody mass fell from within me. I knew that I could not flush this away, and that to retrieve the mass was my only chance to connect with the unborn foetus. I fished the contents from the bottom of the toilet bowl using my hands and carried them into my small studio. I found some paper and began to dissect the mass. At the centre, I found the tiny, cold, hard foetus. I kissed it and then began to use it as a kind of painting tool, drawing the outline of the lost child using its very own flesh and blood. I knew that to create a lasting and tangible portrait of 'my son' was the best way to understand the somewhat unreal and fleeting experience of miscarriage. I thought of Frida Kahlo while making the work, thinking 'thank God' that I had a reference to miscarriage before it happened to me. I also thought of my childhood days spent on our family pig farm, and of all the dead pig foetuses that I had seen at various stages of development. Before the miscarriage, I thought little about the subject; afterwards, I recognise the profundity of the creation of a life that is never born. The experience is so common, yet so very rarely discussed or depicted.

Assessing the impact of ambient ozone on growth and yield of a rice (Oryza sativa L.) and a wheat (Triticum aestivum L.) cultivar grown in the Yangtze Delta, China, using three rates of application of ethylenediurea (EDU)

International Nuclear Information System (INIS)

Wang Xiaoke; Zheng Qiwei; Yao Fangfang; Chen Zhan; Feng Zhaozhong; Manning, W.J.

2007-01-01

Foliar applications of ethylenediurea (abbreviated as EDU) were made at 0, 150, 300 or 450 ppm to field-grown rice and wheat in the Yangtze Delta in China. Rice and wheat responded differently to ambient ozone and EDU applications. For wheat, some growth characteristics, such as yield, seed number per plant, seed set rate and harvest index, increased significantly at 300 ppm EDU treatment, while for rice no parameters measured were statistically different regarding EDU application. The reason may be that the wheat cultivar used may be more sensitive to ozone than the rice cultivar. EDU was effective in demonstrating ozone effects on the wheat cultivar, but not on the rice cultivar. Cultivar sensitivity might be an important consideration when assessing the effects of ambient ozone on plants. - Cultivar sensitivity should be considered when using protective chemical to assess the effects of ambient ozone on plants

Karl Ove Knausgaard's My Struggle

DEFF Research Database (Denmark)

Schmitt, Arnaud; Kjerkegaard, Stefan

2016-01-01

In this study of Karl Ove Knausgaard’s My Struggle, the authors theorize what paratextual information does to one’s reading, especially in autobiography informed literature. Although My Struggle can be read both as memoir and novel, and even as autofiction, Knausgaard is aiming at a higher truth...

5 CFR 839.622 - Can I cancel my FERS election if my qualifying retirement coverage error was previously corrected...

Science.gov (United States)

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Can I cancel my FERS election if my qualifying retirement coverage error was previously corrected and I now have an election opportunity under... ERRONEOUS RETIREMENT COVERAGE CORRECTIONS ACT Making an Election Fers Elections § 839.622 Can I cancel my...

Laboratorio de PHP y MySQL, febrer 2010

OpenAIRE

Berni Millet, Pietro; Gil de la Iglesia, Dídac

2010-01-01

El Laboratori de PHP i MySQL és un espai de pràctiques compartit per diverses assignatures de la UOC que tenen en comú un Sistema de Gestió de Bases de Dades (SGBD) d'arquitectura LAMP (Apache + PHP + MySQL). El Laboratorio de PHP y MySQL es un espacio de prácticas compartido por varias asignaturas de la UOC que tienen en común un Sistema de Gestión de Bases de Datos (SGBD) de arquitectura LAMP (Apache + PHP + MySQL). The PHP and MySQL Laboratory is a practical space shared by the UOC s...

5 CFR 839.1114 - Will OPM actuarially reduce my benefit if I elect to change my retirement coverage under these...

Science.gov (United States)

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Will OPM actuarially reduce my benefit if... General Provisions § 839.1114 Will OPM actuarially reduce my benefit if I elect to change my retirement... Basic Employee Death Benefit (see § 839.1121). ...

Nikolai Borisovich Delone in my life

Science.gov (United States)

Ammosov, M. V.

2009-08-01

Nikolai Delone has literally dragged me to science. I owe him my scientific carrier. In addition he taught me diligence, responsibility, purposefulness, and theoretical and experimental skills that were helpful in all my life.

41 CFR 302-9.173 - How many replacement POV's may my agency authorize me to transport to my post of duty at...

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false How many replacement POV's may my agency authorize me to transport to my post of duty at Government expense? 302-9.173... How many replacement POV's may my agency authorize me to transport to my post of duty at Government...

Co-transfer of gfp, CHS and hptII genes into Oncidium Sharry Baby ...

African Journals Online (AJOL)

STORAGESEVER

2008-08-04

Aug 4, 2008 ... 3Malaysian Institute for Nuclear Technology Research (MINT), Bangi, 43000, ... Key words: Biolistic gun, co-transformation, orchidaceae, protocorm-like-body. ... *Corresponding author: E-mail: janna@biotech.upm.edu.my.

How I Left My Comfort Zone in Pure Mathematics

Directory of Open Access Journals (Sweden)

Şeyda UYSAL

2016-12-01

Full Text Available Why am I writing a diary? What did I gain by writing a diary? When I write randomly on a piece of paper, it gives me inspiration about my life and about my academic plans. I discovered my interests with writing practice, and I thought sharing my story with others might be a good idea. I studied mathematics as my major. When I was a senior, I already felt tired of abstract mathematics. Psychology of education could be better for me, or another field which has its concrete application in real life. However, at the same time, I did not want to move away from mathematics. Then I met the Department of Education, and I started to take some classes related to education to get ready for my teaching carrier. Because with some background in pedagogy, I knew that I would be able to be more helpful to my students in the future. Then I realized that some mathematical issues which my professors probably worked on for hours were quite barren and not useful for my purposes: teaching mathematics, I mean, usable mathematics that is lots of fun! When I started teaching after having my bachelor’s degree, the biggest challenge for me was to motivate my students. The classroom had good materials and I had the skills to solve the advanced problem sets in mathematics. But how could I find the opportunity to have good communication with my students? These years were worse than my college years. I loved mathematics and I did not understand why they did not! I pondered and made observations about it for almost a year, and I realized that there could be a bigger reason; not related to me personally or to math. I kept records of my teaching experience and wrote down my opinions daily. My husband and I discussed specific problematic situations in the classroom. Finally I happened to figure it out that I decided to leave my comfort zone. What was my comfort zone? It was where I felt safe and what I felt comfortable in doing. I was solving mathematics problems by myself, but

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African Journals Online (AJOL)

2018-01-15

Jan 15, 2018 ... possesses phytochemical compound that was non cytotoxic to the cell with potential antiviral activity. These species are ... Author Correspondence, e-mail: zarinawahab@unisza.edu.my .... inverted microscope. To determine ...

My Friend Is Talking about Suicide

Science.gov (United States)

... Search English Español My Friend Is Talking About Suicide. What Should I Do? KidsHealth / For Teens / My ... sobre suicidio. ¿Qué debo hacer? Warning Signs of Suicide Everyone feels sad, depressed, or angry sometimes — especially ...

My journey to DNA repair.

Science.gov (United States)

Lindahl, Tomas

2013-02-01

I completed my medical studies at the Karolinska Institute in Stockholm but have always been devoted to basic research. My longstanding interest is to understand fundamental DNA repair mechanisms in the fields of cancer therapy, inherited human genetic disorders and ancient DNA. I initially measured DNA decay, including rates of base loss and cytosine deamination. I have discovered several important DNA repair proteins and determined their mechanisms of action. The discovery of uracil-DNA glycosylase defined a new category of repair enzymes with each specialized for different types of DNA damage. The base excision repair pathway was first reconstituted with human proteins in my group. Cell-free analysis for mammalian nucleotide excision repair of DNA was also developed in my laboratory. I found multiple distinct DNA ligases in mammalian cells, and led the first genetic and biochemical work on DNA ligases I, III and IV. I discovered the mammalian exonucleases DNase III (TREX1) and IV (FEN1). Interestingly, expression of TREX1 was altered in some human autoimmune diseases. I also showed that the mutagenic DNA adduct O(6)-methylguanine (O(6)mG) is repaired without removing the guanine from DNA, identifying a surprising mechanism by which the methyl group is transferred to a residue in the repair protein itself. A further novel process of DNA repair discovered by my research group is the action of AlkB as an iron-dependent enzyme carrying out oxidative demethylation. Copyright © 2013. Production and hosting by Elsevier Ltd.

Is My Penis Normal? (For Teens)

Science.gov (United States)

... Videos for Educators Search English Español Is My Penis Normal? KidsHealth / For Teens / Is My Penis Normal? Print en español ¿Es normal mi pene? ... any guy who's ever worried about whether his penis is a normal size. There's a fairly wide ...

41 CFR 302-3.422 - What expenses will my agency pay when I complete my TCS?

Science.gov (United States)

2010-07-01

... Separation from Government Service § 302-3.422 What expenses will my agency pay when I complete my TCS? Your...; (c) Transportation of a mobile home instead of transportation of our household goods under part 302... privately owned vehicle(s) under part of this chapter; and (g) A relocation income tax allowance under part...

My 2030s. Citizens about the Biobased Economy; My 2030s. Burgers over de Biobased Economy

Energy Technology Data Exchange (ETDEWEB)

Van den Berg, N.; Hulshof, M.; Van der Veen, M.

2013-02-15

My 2030s is the first qualitative study of the needs and concerns of citizens about the Biobased Economy, an economy in which fossil fuels are largely substituted by vegetable alternatives. This final report describes the reason and purpose of My 2030s, the course of the public debates and the results of research into ideas of citizens on the Biobased Economy The report concludes with recommendations on how the stakeholders can actively involve citizens in one of the major transitions of the next century [Dutch] My 2030s is het eerste kwalitatieve onderzoek naar de wensen en zorgen van burgers over de Biobased Economy, een economie waarin fossiele grondstoffen grotendeels zijn vervangen door plantaardige alternatieven. Dit eindrapport beschrijft de aanleiding en opzet van My 2030s, het verloop van de publieksdebatten en de resultaten van het onderzoek naar denkbeelden van burgers over de Biobased Economy. Het rapport eindigt met aanbevelingen over hoe de stakeholders burgers actief kunnen betrekken bij een van de belangrijkste transities van de komende eeuw.

Deep Reflection on My Pedagogical Transformations

Science.gov (United States)

Suzawa, Gilbert S.

2014-01-01

This retrospective essay contains my reflection on the deep concept of ambiguity (uncertainty) and a concomitant epistemological theory that all of our human knowledge is ultimately self-referential in nature. This new epistemological perspective is subsequently utilized as a platform for gaining insights into my experiences in conjunction with…

Can Loud Music Hurt My Ears?

Science.gov (United States)

... Videos for Educators Search English Español Can Loud Music Hurt My Ears? KidsHealth / For Kids / Can Loud Music Hurt My Ears? Print en español La música ... up? Oh! You want to know if loud music can hurt your ears . Are you asking because ...

My idol

Institute of Scientific and Technical Information of China (English)

胡姝慧

2002-01-01

An idol is a person who is admired by many other people. Everybody has his own idol. The idol may be a scientist, an artist, a singer or a politician.My classmates' idols are many superstars, for example, Jordan, Pele, Liu Dehua and so on.

My Way in Archaeomagnetism

Science.gov (United States)

Kovacheva, Mary

2014-05-01

The talk describes the main hallmarks in my nearly half a century activity in the field of archaeomagnetism. Beginning from zero in my country in 1967, now the Bulgarian database is the longest data set comprising the three geomagnetic characteristics. I consider that the determination of the direction and absolute palaeointensity from one and the same material is the most valuable input data for the important geomagnetic field modeling. The recovered full geomagnetic vector gives much more opportunities for different geophysical applications. The maintenance, filling up and revision of the local database remained my principle obligation during my professional way. As a result taking the advantage of our country to have plenty of prehistoric single and multilevel sites the knowledge of the geomagnetic field behavior was prolonged deeply in the past going to 6000 yrs BC. The usage of 14C dates will be discussed describing possible difficulties which can be encountered. The specific multilevel prehistoric sites, found mostly in the Near East and the Balkans, with clear stratigraphy are particularly useful for archaeomagnetic discovery of the past geomagnetic field behavior. In this respect the well-timed activity of geophysical teams following the archaeological excavations is very important for the future elucidation of geomagnetic secular variations. The constant tight contact with the archaeological community of each country during this process is crucial. Examples of most valuable topics of interest for archaeologists will be given in the talk as synchronizations, magnetic characteristics related to the type of ceramics, archaeomagnetic dating etc. This is an important task because we should keep their interest towards our studies giving us the necessary materials. Some obtained questionable results will be discussed parallel with the progress in understanding the physical processes in baked clay and its magnetic mineralogy. Going deeply in diagnosis of the

"I Can See You": An Autoethnography of My Teacher-Student Self

Science.gov (United States)

Vasconcelos, Erika Franca de Souza

2011-01-01

This article is an autoethnographic investigation of my second-nature teacher-student self. What has made me into the teacher I am? What makes me the teacher I am? I draw upon my memories of my own teachers and students to address these questions. As I portray my teaching-learning experiences as textual "snapshots," I find that my dearest memories…

MyShake - Smartphone seismic network powered by citizen scientists

Science.gov (United States)

Kong, Q.; Allen, R. M.; Schreier, L.; Strauss, J. A.

2017-12-01

MyShake is a global smartphone seismic network that harnesses the power of crowdsourcing. It is driven by the citizen scientists that run MyShake on their personal smartphones. It has two components: an android application running on the smartphones to detect earthquake-like motion, and a network detection algorithm to aggregate results from multiple smartphones to confirm when an earthquake occurs. The MyShake application was released to the public on Feb 12th 2016. Within the first year, more than 250,000 people downloaded MyShake app around the world. There are more than 500 earthquakes recorded by the smartphones in this period, including events in Chile, Argentina, Mexico, Morocco, Greece, Nepal, New Zealand, Taiwan, Japan, and across North America. Currently, we are working on earthquake early warning with MyShake network and the shaking data provided by MyShake is a unique dataset that can be used for the research community.

MyFoodAdvisor

Science.gov (United States)

... Pot Salad Dressings & Condiments Sandwiches Sauces Sides Snacks Vegan Vegetarian Salads Lunch Dinner Soup My Likes Ingredients ... Pot Salad Dressings & Condiments Sandwiches Sauces Sides Snacks Vegan Vegetarian Salads Lunch Dinner Soup Apply Cancel Reset ...

Writing My Way to My Future | Poster

Science.gov (United States)

By Nathalie Walker, Guest Writer Editor’s note: This article is the second in a series describing one student’s perspective on her experiences as a Werner H. Kirsten student intern. “The future depends on what you do today.” Those wise words were spoken by Mahatma Gandhi. Before I started my Werner H. Kirsten (WHK) student internship, I did not know what I know now. I only

25 CFR 256.21 - Will I have to vacate my dwelling while repair work or replacement of my dwelling is being done?

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Will I have to vacate my dwelling while repair work or replacement of my dwelling is being done? 256.21 Section 256.21 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HOUSING HOUSING IMPROVEMENT PROGRAM § 256.21 Will I have to vacate my dwelling while...

EduGeoPark: international students exchanges for promoting Earth Science knowledge and Geoheritage awareness

Science.gov (United States)

Giardino, Marco; Magagna, Alessandra; Dellarole, Edoardo; Kiuttu, Mikko

2015-04-01

Geoparks are the ideal destination for international study tours based on the sustainable tourism concept, in which the travel is conceived as an opportunity for sharing both scientific knowledge and intangible and tangible culture. Equally, they are the appropriate places for testing and practicing innovative educational strategies, shareable in an international context. The innovative idea of EduGeoPark project is to involve students and teachers in research activities in Geoparks, including sampling and digital mapping: practical field and laboratory activities for stimulating the geological interpretation of an unknown territory. An approach devoted to improve teamwork and problem solving competences. By means of a partnerships between the Rokua (Finland) and the Sesia-Val Grande (Italy) Geoparks, an exchange program for Secondary School's students started during 2014 (Vaala High School; I.I.S. Luigi Cobianchi High School in Verbania). The study and the visit of both territories was an opportunity for students to observe some relevant geological elements and processes that do not exist in their own country. Moreover, the hosting in families allowed them to feel the culture of the area. Teachers and staff of the Geoparks led field trips to the main geological and cultural attractions of both areas. During the activities, students used mobile devices (smartphone and tablet) and GPS to track field trips, to catch and gather georeferenced data and pictures. They acted as researchers, by using both digital and traditional tools: they observed, asked questions, gathered data, and made hypothesis. By sharing ideas, together with the local guides, they reconstructed the cultural and geological history of the area. Students appreciated the experience: not only they had the opportunity of visiting a different country, but also of deepening the geological awareness on their own territory. EduGeoPark project is opening the participation to other Geoparks, in order to

Learning PHP, MySQL, and JavaScript

CERN Document Server

Nixon, Robin

2009-01-01

If you know HTML, this guide will have you building interactive websites quickly. You'll learn how to create responsive, data-driven websites with PHP, MySQL, and JavaScript, regardless of whether you already know how to program. Discover how the powerful combination of PHP and MySQL provides an easy way to build modern websites complete with dynamic data and user interaction. You'll also learn how to add JavaScript to create rich Internet applications and websites. Learning PHP, MySQL, and JavaScript explains each technology separately, shows you how to combine them, and introduces valuable

My NASA Data

Data.gov (United States)

National Aeronautics and Space Administration — MY NASA DATA (MND) is a tool that allows anyone to make use of satellite data that was previously unavailable.Through the use of MND’s Live Access Server (LAS) a...

Introducción a phpMyAdmin (2/4)

OpenAIRE

Suárez Cueto, Armando

2012-01-01

Curso "Introducción al desarrollo web": phpMyAdmin, creación de tablas, tipos de datos, creación de índices, motores de MySQL (INNODB, MyISAM, MEMORY), inserción de datos, seguimiento de una tabla (historial), exportar una tabla (backup). Más información: http://idesweb.es

Diary of an Edu-Tourist in Costa Rica: An Autoethnographical Account of Learning Spanish

Science.gov (United States)

Lotherington, Heather

2007-01-01

This article presents an autoethnographical account of my foray into Spanish immersion education in Costa Rica as a professor of multilingual education at a university in Canada. This language-learning journey was inspired by curiosity about the growing trend for Internet marketing of second-language learning as a form of tourism, which I label…

Examination of the Film "My Father and My Son" According to the Basic Concepts of Multigenerational Family Therapy

Science.gov (United States)

Acar, Tulin; Voltan-Acar, Nilufer

2013-01-01

The aim of this study was to evaluate the basic concepts of multigenerational Family Therapy and to evaluate the scenes of the film ''My Father and My Son'' according to these concepts. For these purposes firstly basic concepts of Multigenerational Family Therapy such as differentiation of self, triangles/triangulation, nuclear family emotional…

IOS SAFETY APPLICATION FOR UITM

Directory of Open Access Journals (Sweden)

MOHAMAD FAHMI HUSSIN

2016-04-01

Full Text Available This paper presents an iOS application, which is developed, to ensure that every task related to safety and health such as inspection, deviation analysis and accident reporting becomes more simple and easier. Normally, these three (3 tasks are done separately and the data are saved in different ways. These situations make the tasks become complicated and consume a lot of time. Therefore, this application is developed to overcome all the problems that occurred. The main objective of this application is to allow the user to handle inspection checklist, deviation analysis and accident reporting efficiently by using iOS devices such as iPhone and iPad. Hence, using iOS device, instead of using a lot of paper, can do all the tasks. Using Xcode SDK, which is the software that is used to develop iOS application, developed this application. Xcode use Objective-C as the programming language, which is quite similar with other programming languages such as C and C++. The final result of this project is that this application can handle all the three (3 tasks and the form or the findings can be emailed to the Safety and Health Officer (SHO. This application will reduce time consume to conduct safety inspection, deviation and reporting tasks as well as avoid delay that might happen while using the traditional method.

MyOcean Information System : achievements and perspectives

Science.gov (United States)

Loubrieu, T.; Dorandeu, J.; Claverie, V.; Cordier, K.; Barzic, Y.; Lauret, O.; Jolibois, T.; Blower, J.

2012-04-01

MyOcean system (http://www.myocean.eu) objective is to provide a Core Service for the Ocean. This means MyOcean is setting up an operational service for forecasts, analysis and expertise on ocean currents, temperature, salinity, sea level, primary ecosystems and ice coverage. The production of observation and forecasting data is distributed through 12 production centres. The interface with the external users (including web portal) and the coordination of the overall service is managed by a component called service desk. Besides, a transverse component called MIS (myOcean Information System) aims at connecting the production centres and service desk together, manage the shared information for the overall system and implement a standard Inspire interface for the external world. 2012 is a key year for the system. The MyOcean, 3-year project, which has set up the first versions of the system is ending. The MyOcean II, 2-year project, which will upgrade and consolidate the system is starting. Both projects are granted by the European commission within the GMES Program (7th Framework Program). At the end of the MyOcean project, the system has been designed and the 2 first versions have been implemented. The system now offers an integrated service composed with 237 ocean products. The ocean products are homogeneously described in a catalogue. They can be visualized and downloaded by the user (identified with a unique login) through a seamless web interface. The discovery and viewing interfaces are INSPIRE compliant. The data production, subsystems availability and audience are continuously monitored. The presentation will detail the implemented information system architecture and the chosen software solutions. Regarding the information system, MyOcean II is mainly aiming at consolidating the existing functions and promoting the operations cost-effectiveness. In addition, a specific effort will be done so that the less common data features of the system (ocean in

Lessons learned from the birth and evolution of the EduFinland virtual community for educators

Directory of Open Access Journals (Sweden)

Kim Holmberg

2012-03-01

Full Text Available Educators around the world are experimenting with the possibilities virtual three dimensional worlds have for education and learning how to use these new environments efficiently. Virtual worlds have the potential to bring some new added value to education and educators can use them to create something that is not possible to do or show in traditional classrooms. Although a lot have been learned about virtual worlds and their potential, a lot more has to be learned before virtual worlds can become an integrated part of education on various levels. The article looks back at the birth and growth of the EduFinland community in the virtual world of Second Life and discusses lessons learned so far during the years of its existence.

PHP and MySQL 24-Hour Trainer

CERN Document Server

Tarr, Andrea

2011-01-01

Step-by-step lessons for using PHP and MySQL in a unique book-and-video combination Assuming no previous experience with PHP or MySQL, this book-and-video package is ideal reading for anyone who wants to go beyond HTML/CSS in order to provide clients with the most dynamic web sites possible. The approachable tone breaks down the basics of programming and PHP and MySQL in individual lessons starting with the installation of the programs necessary to run PHP. You begin with a static web site and then watch and learn as PHP functionality is added as you work through the lessons. When working w

An Initial Evaluation of a Comprehensive Continuing Care Intervention for Clients with Substance Use Disorders: My First Year of Recovery (MyFYR).

Science.gov (United States)

McKay, James R; Knepper, Cheryl; Deneke, Erin; O'Reilly, Christopher; DuPont, Robert L

2016-08-01

Physician health programs (PHPs) generate high rates of sustained abstinence in addicted physicians, through a combination of formal treatment, self-help involvement, regular monitoring via random urine toxicology tests, and powerful incentives generated by the threat of losing one's medical license. Recently, Caron Treatment Centers developed a new continuing care intervention, "My First Year of Recovery" (MyFYR), which is modeled after PHPs but provides extended recovery support to a broader segment of those with substance use disorders. This paper presents initial outcome data from MyFYR. MyFYR features frequent outcomes monitoring via urine toxicology tests, and also includes a web-based social platform to coordinate efforts of recovery coaches, family members, and others (e.g., employers, probation officers). Participants were the first 198 clients who enrolled in MyFYR after participating in residential treatment at Caron. Substance use outcomes were determined by a combination of urine toxicology tests, client self-report, and information from family members obtained during a 12-month period following entry into MyFYR. Clients in MyFYR provided 70% of scheduled urine samples, for an average of 16.4 urine samples per client. Only 4.1% of the samples tested positive for alcohol or any drug. As determined by urine toxicology and client and family reports, 54% of the participants had some use of alcohol or drugs during the follow-up. Of these relapsed clients, 70.1% were retained or re-engaged in MyFYR, and of these, half were able to re-establish abstinence of two months duration or more, as documented by urine toxicology. These initial results are extremely promising, as they document high rates of sustained participation in urine drug test monitoring and positive outcome in clients not under the threat of losing a professional license or incarceration. Copyright © 2016 Elsevier Inc. All rights reserved.

Self-Presentation and Gender on MySpace

Science.gov (United States)

Manago, Adriana M.; Graham, Michael B.; Greenfield, Patricia M.; Salimkhan, Goldie

2008-01-01

Within the cultural context of MySpace, this study explores the ways emerging adults experience social networking. Through focus group methodology, the role of virtual peer interaction in the development of personal, social, and gender identities was investigated. Findings suggest that college students utilize MySpace for identity exploration,…

Why Are My Breasts Different Sizes? (For Teens)

Science.gov (United States)

... Feelings Expert Answers Q&A Movies & More for Teens Teens site Sitio para adolescentes Body Mind Sexual Health ... Why Are My Breasts Different Sizes? KidsHealth / For Teens / Why Are My Breasts Different Sizes? Print Having ...

Research Article Special Issue

African Journals Online (AJOL)

pc

2017-11-10

Nov 10, 2017 ... find the important of Mathematical skills for future career development. ... opportunities. ... University of Technology (UiTM), the concerns regarding poor performance ... Therefore, this study was conducted to find the lecturers'.

Who is my Jung? A personal and symbolic history.

Science.gov (United States)

Fitzgerald, Jim

2018-06-01

Identifying the reality of Jung in my life requires first of all a historical examination. How Jung first came into my life through my reading a book by P.W.Martin, Experiment in Depth, stands as a metaphor for the conscious unravelling of psychological development. His further appearance in a sequence of dreams demonstrated the significance of both the instinctual and the numinous in Jung's life and in my personal individuation. Finally, through a consideration of light and shadow, particularly in two photographs of Jung, a conclusion is reached that individuation requires an integration of shadow in the personality, in order to achieve wholeness, not perfection. © 2018, The Society of Analytical Psychology.

My fuel treatment planner: a user guide.

Science.gov (United States)

Robin L. Biesecker; Roger D. Fight

2006-01-01

My Fuel Treatment Planner (MyFTP) is a tool for calculating and displaying the financial costs and potential revenues associated with forest fuel reduction treatments. It was designed for fuel treatment planners including those with little or no background in economics, forest management, or timber sales. This guide provides the information needed to acquire, load, and...

Cleanups in My Community

Data.gov (United States)

U.S. Environmental Protection Agency — Cleanups in My Community (CIMC) is a public web application that enables integrated access through maps, lists and search filtering to site-specific information EPA...

41 CFR 302-10.206 - May my agency assume direct responsibility for the costs of preparing and transporting my mobile...

Science.gov (United States)

2010-07-01

... direct responsibility for the costs of preparing and transporting my mobile home? 302-10.206 Section 302... ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 10-ALLOWANCES FOR TRANSPORTATION OF MOBILE HOMES AND BOATS... responsibility for the costs of preparing and transporting my mobile home? Yes, your agency may assume direct...

MyPlate Daily Checklist

Science.gov (United States)

... Price Tag Read the Food Label Kitchen Timesavers Cooking for Your Family Tasty & Low-Cost Recipes Sample 2-Week Menus Resources for Professionals MyPlate Tip Sheets Print Materials Infographics 5 Ways ...

Interferon-inducible MyD88 protein inhibits hepatitis B virus replication

International Nuclear Information System (INIS)

Xiong Wei; Wang Xun; Liu Xiaoying; Xiang Li; Zheng Lingjie; Yuan Zhenghong

2004-01-01

Myeloid differential primary response protein (MyD88) is a critical component in the signaling cascade through Toll-like receptors (TLRs) and is induced by α interferon (IFN-α). To examine the role of MyD88 in the antiviral activity of IFN-α against hepatitis B virus (HBV), we established MyD88 stably expressing cell lines and studied HBV replication in these lines after transient transfection. The levels of HBV proteins and viral replicative intermediates were effectively reduced in MyD88-expressing cells. A significant reduction of total and cytoplasmic viral RNAs in MyD88 stably expressing cells was also observed. Using a nuclear factor-κB (NF-κB) dependent reporter assay, it was shown that activation of NF-κB was moderately increased in the presence of expression of MyD88, and further significantly increased by co-expression of HBV. These results suggest a novel mechanism for the inhibition of HBV replication by IFN-α via expression of MyD88 protein involving activation of NF-κB signaling pathway and downregulation of viral transcription

Drawing together psyche, soma and spirit: my career in cultural psychiatry.

Science.gov (United States)

Dein, Simon

2011-04-01

In this article I discuss my career in cultural psychiatry. I begin by examining the influence of my personal background on my interests in cultural psychiatry and religion and health. I then discuss my research, which has focused upon two areas: the cognitive and phenomenological parallels between religious experiences and psychopathological states, and relationships between biomedicine and religious healing in diverse cultural contexts. Finally, I discuss plans for future research and teaching.

Evolution of Theoretical Perspectives in My Research

Science.gov (United States)

Otero, Valerie K.

2009-11-01

Over the past 10 years I have been using socio-cultural theoretical perspectives to understand how people learn physics in a highly interactive, inquiry-based physics course such as Physics and Everyday Thinking [1]. As a result of using various perspectives (e.g. Distributed Cognition and Vygotsky's Theory of Concept Formation), my understanding of how these perspectives can be useful for investigating students' learning processes has changed. In this paper, I illustrate changes in my thinking about the role of socio-cultural perspectives in understanding physics learning and describe elements of my thinking that have remained fairly stable. Finally, I will discuss pitfalls in the use of certain perspectives and discuss areas that need attention in theoretical development for PER.

User Satisfaction Assessment To Edu-Eco Tourism Services Of Cibodas Botanical Garden

Science.gov (United States)

Hidayat, I. W.; Winarni

2017-10-01

Cibodas Botanical Garden (CBG) is a government institution which has principal duties and functions as area of conservation ex situ of wet highland plants, research, education and tourism, it very closely related to aspect of the services to user. Good services will support the sustainability and existence of CBG as a world class edu-eco tourism destination. The purpose of this study was to measure the quality of services which delivered and improvement which necessary at the future. Assessments were made based on 14 criteria of services aspect for user which need research-education services and regular tourism services activities. The study was conducted by distributing questionnaires to users of these services. Questionnaires distribution was conducted in early August 2015 and August 2016, the respondents were 124 and 207. The results were showed the user satisfaction at good level, there were 77.685 in 2015 and 72.08 in 2016. Although still at a good level, there were a decline in satisfaction levels based on the value. In the future, the managerial needs to continuously to improve it, in order to get a good or very good valuation.

Contributions of co-curricular summer research programs to my professional growth

Science.gov (United States)

Moore, K. D.

2014-12-01

The co-curricular summer research program, in which I was involved over three summers as an undergraduate student, greatly benefited me. In this paper I will briefly describe the program and how the experience contributed to my value and growth. The U.S. Department of Energy operated the Global Change Education Program (GCEP), from 1999-2013, as an outreach to both undergraduate and graduate students. Its goals were to: provide students with hands-on research experience in a one-on-one setting with leaders in global change fields, encourage undergraduate students to enter graduate school, and increase the number of high quality U.S. scientists. I took part in GCEP as a Summer Undergraduate Research Experience (SURE) Fellow. Each Fellow was teamed with a scientist to conduct research over the summer. I spent one summer at Pacific Northwest National Laboratory in Richland, WA working with Dr. William Shaw. The next two summers I spent working at Aerodyne Research, Inc. in Billerica, MA with Dr. Leah Williams. My experiences as a SURE Fellow have benefitted me in many ways. The research presentations, required of SURE Fellows, helped to improve my presentation skills. The GCEP workshops expanded the scope of my knowledge about global change impacts at all scales. I was involved in two large, collaborative field studies, which provided experiences and examples that have helped me lead my own field studies. I took part in well-functioning research teams, helping me see the value of open communication in collaborative work. My critical and analytical thinking abilities were continually honed. My problem solving skills were challenged in laboratory and field work. I worked with talented professionals and students that are now part of my professional network. My contributions resulted in being a coauthor on two peer-reviewed publications. I was able to experience research teams outside of academia, which included government and private sectors. The time spent as a SURE

29 CFR 1472.220 - By when must I publish my drug-free workplace statement and establish my drug-free awareness...

Science.gov (United States)

2010-07-01

... 29 Labor 4 2010-07-01 2010-07-01 false By when must I publish my drug-free workplace statement and establish my drug-free awareness program? 1472.220 Section 1472.220 Labor Regulations Relating to Labor (Continued) FEDERAL MEDIATION AND CONCILIATION SERVICE GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements...

Universe unveiled the cosmos in my bubble bath

CERN Document Server

Vishveshwara, C V

2015-01-01

The bubbles were swirling all around me, massaging my body. As I luxuriated in this fantastic bath, I gasped realizing that those bubbles carried with them miniature galaxies bringing the entire Cosmos into my bathtub... Alfie is back. And so are George and other characters from the author’s previous book Einstein’s Enigma or Black Holes in My Bubble Bath. While the present book, Universe Unveiled - The Cosmos in My Bubble Bath, is completely independent, its storyline can be considered a sequel to the previous one. The scientific content spanning ancient world models to the most recent mysteries of cosmology is presented in an entirely nontechnical and descriptive style through the discussions between Alfie, the enlightened learner, and George, professor of astrophysics. Fantasies, based on these discussions that cover the scientific facts, are created by the magical bubble baths taken by Alfie. Universe Unveiled blends accurate science with philosophy, drama, humour, and fantasy to create an exciting co...

43 CFR 43.220 - By when must I publish my drug-free workplace statement and establish my drug-free awareness...

Science.gov (United States)

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false By when must I publish my drug-free workplace statement and establish my drug-free awareness program? 43.220 Section 43.220 Public Lands: Interior Office of the Secretary of the Interior GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients...

Research Article Special Issue

African Journals Online (AJOL)

pc

2017-10-17

Oct 17, 2017 ... the evaluation of fatigue crack growth rate for iron-carbon metals py generation theorem. ... C steel. mail: shahrum@ukm.edu.my. /10.4314/jfas.v9i5s.37 ... f the present model are .... the shear modulus and σy the yield stress.

PROBLEMS IN TOPOLOGICAL GRAPH THEORY : QUESTIONS I CAN'T ANSWER

OpenAIRE

Archdeacon, Dan

1999-01-01

This paper describes my Problems in Topological Graph Theory, which can be accessed through the world-wide-web at http: //www.emba .uvm.edu/~arcceack/problems/problems.html This list of problems is constantly being revised; the interested reader is encouraged to submit additions and updates.

41 CFR 105-74.220 - By when must I publish my drug-free workplace statement and establish my drug-free awareness...

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false By when must I publish my drug-free workplace statement and establish my drug-free awareness program? 105-74.220 Section 105-74.220 Public Contracts and Property Management Federal Property Management Regulations System...

Synthesis and antibacterial profile of novel azomethine derivatives ...

African Journals Online (AJOL)

3, Banjara hills, Hyderabad, India, 3Universiti Teknologi MARA. (UiTM), Faculty of Pharmacy, Puncak Alam Campus, Selangor D.E, Malaysia ... Results: The structures of azomethine were in full agreement with their spectral data. Among all ...

Using PHP/MySQL to Manage Potential Mass Impacts

Science.gov (United States)

Hager, Benjamin I.

2010-01-01

This paper presents a new application using commercially available software to manage mass properties for spaceflight vehicles. PHP/MySQL(PHP: Hypertext Preprocessor and My Structured Query Language) are a web scripting language and a database language commonly used in concert with each other. They open up new opportunities to develop cutting edge mass properties tools, and in particular, tools for the management of potential mass impacts (threats and opportunities). The paper begins by providing an overview of the functions and capabilities of PHP/MySQL. The focus of this paper is on how PHP/MySQL are being used to develop an advanced "web accessible" database system for identifying and managing mass impacts on NASA's Ares I Upper Stage program, managed by the Marshall Space Flight Center. To fully describe this application, examples of the data, search functions, and views are provided to promote, not only the function, but the security, ease of use, simplicity, and eye-appeal of this new application. This paper concludes with an overview of the other potential mass properties applications and tools that could be developed using PHP/MySQL. The premise behind this paper is that PHP/MySQL are software tools that are easy to use and readily available for the development of cutting edge mass properties applications. These tools are capable of providing "real-time" searching and status of an active database, automated report generation, and other capabilities to streamline and enhance mass properties management application. By using PHP/MySQL, proven existing methods for managing mass properties can be adapted to present-day information technology to accelerate mass properties data gathering, analysis, and reporting, allowing mass property management to keep pace with today's fast-pace design and development processes.

41 CFR 301-10.308 - What will I be reimbursed if I park my POV at a common carrier terminal while I am away from my...

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What will I be reimbursed if I park my POV at a common carrier terminal while I am away from my official station? 301-10.308... am away from my official station? Your agency may reimburse your parking fee as an allowable...

Stem cell survival is severely compromised by the thymidineanalog EdU (5-ethynyl-2'-deoxyuridine), an alternative to BrdU for proliferation assays and stem cell tracing

DEFF Research Database (Denmark)

Andersen, Ditte C; Skovrind, Ida; Christensen, Marlene Louise

2013-01-01

Stem cell therapy has opened up the possibility of treating numerous degenerating diseases. However, we are still merely at the stage of identifying appropriate sources of stem cells and exploring their full differentiation potential. Thus, tracking the stem cells upon in vivo engraftment...... and during in vitro co-culture is very important and is an area of research embracing many pitfalls. 5-Ethynyl-2'-deoxyuridine (EdU), a rather new thymidine analog incorporated into DNA, has recently been suggested to be a novel highly valid alternative to other dyes for labeling of stem cells and subsequent...... tracing of their proliferation and differentiation ability. However, our results herein do not at any stage support this recommendation, since EdU severely reduces the viability of stem cells. Accordingly, we found that transplanted EdU-labeled stem cells hardly survive upon in vivo transplantation...

'My kidneys, my choice, decision aid': supporting shared decision making.

Science.gov (United States)

Fortnum, Debbie; Smolonogov, Tatiana; Walker, Rachael; Kairaitis, Luke; Pugh, Debbie

2015-06-01

For patients with chronic kidney disease (CKD) who are progressing to end-stage kidney disease (ESKD) a decision of whether to undertake dialysis or conservative care is a critical component of the patient journey. Shared decision making for complex decisions such as this could be enhanced by a decision aid, a practice which is well utilised in other disciplines but limited for nephrology. A multidisciplinary team in Australia and New Zealand (ANZ) utilised current decision-making theory and best practice to develop the 'My Kidneys, My Choice', a decision aid for the treatment of kidney disease. A patient-centred, five-sectioned tool is now complete and freely available to all ANZ units to support the ESKD education and shared decision-making process. Distribution and education have occurred across ANZ and evaluation of the decision aid in practice is in the first phase. Development of a new tool such as an ESKD decision aid requires vision, multidisciplinary input and ongoing implementation resources. This tool is being integrated into ANZ, ESKD education practice and is promoting the philosophy of shared decision making. © 2014 European Dialysis and Transplant Nurses Association/European Renal Care Association.

Identification and function of myeloid differentiation factor 88 (MyD88 in Litopenaeus vannamei.

Directory of Open Access Journals (Sweden)

Shuang Zhang

Full Text Available Myeloid differentiation factor 88 (MyD88 is a universal and essential signaling protein in Toll-like receptor/interleukin-1 receptor-induced activation of nuclear factor-kappa B. In this study, two MyD88 protein variants (LvMyD88 and LvMyD88-1 were identified in Litopenaeus vannamei. The LvMyD88 cDNA is 1,848 bp in length and contains an open reading frame (ORF of 1,428 bp, whereas the LvMyD88-1 cDNA is 1,719 bp in length and has an ORF of 1,299 bp. Both variants encode proteins with death and Toll/interleukin-1 receptor domains and share 91% sequence identity. In healthy L. vannamei, the LvMyD88 genes were highly expressed in hemocytes but at a low level in the hepatopancreas. The LvMyD88s expression was induced in hemocytes after challenge with lipopolysaccharide, CpG-ODN2006, Vibrio parahaemolyticus, Staphyloccocus aureus, and white spot syndrome virus, but not by poly I∶C. Overexpression of LvMyD88 and LvMyD88-1 in Drosophila Schneider 2 cells led to activation of antimicrobial peptide genes and wsv069 (ie1, wsv303, and wsv371. These results suggested that LvMyD88 may play a role in antibacterial and antiviral response in L. vannamei. To our knowledge, this is the first report on MyD88 in shrimp and a variant of MyD88 gene in invertebrates.

My 50 years of research in particle physics

International Nuclear Information System (INIS)

Sugawara, Hirotaka

2010-01-01

Some of my work of the last 50 years in the field of theoretical particle physics is described with particular emphasis on the motivation, the process of investigation, relationship to the work of others, and its impact. My judgment is unavoidably subjective, although I do present the comments of other researchers as much as possible. (author)

The pursuit of science – my hobby and profession

Indian Academy of Sciences (India)

Lawrence

hours on my own, daydreaming and imagining things. Initially, because ... My aunt, also a scientist working on cancer ... things, this is what I have been working on for the past 28 years. ... He had just left a sound and prosperous career in USA.

24 CFR 15.112 - How will HUD respond to my appeal?

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false How will HUD respond to my appeal... respond to my appeal? (a) How much time does HUD have to decide my appeal? HUD will decide your appeal of a denial of expedited processing within 10 working days after its receipt. For any other type of...

41 CFR 301-10.117 - May I keep compensation an airline gives me for voluntarily vacating my seat on my scheduled...

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false May I keep compensation an airline gives me for voluntarily vacating my seat on my scheduled airline flight when the airline asks for volunteers? 301-10.117 Section 301-10.117 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY)...

My ADHD and me

DEFF Research Database (Denmark)

Nielsen, Mikka

2017-01-01

In this article, I illustrate how individuals diagnosed with ADHD relate to, engage with, and interpret both ADHD and explanations of the diagnosis. Based on my research on adults’ experiences of ADHD, I describe how my informants 1) identify with ADHD as a specific way of being human as well as 2......) distance themselves from ADHD by separating themselves from and disclaiming behavior connected to ADHD. Notions of ADHD as a brain disorder, I argue, form the basis of both ways of relating to ADHD. Lastly, I discuss how neurobiological explanations of ADHD produce specific choices about and hopes...... for treatment. The analysis is based on interviews with 13 adults diagnosed with ADHD in adulthood; on observations made at conferences and seminars about ADHD for professionals, patients and relatives; and lastly on observations from online blogs and forums about ADHD as part of a two-year anthropological...

My experience learning about autism.

Science.gov (United States)

Rossignol, Daniel A

2013-11-01

I remember the first time I heard the word "autistic." I was 10 years old, and my mom mentioned that someone had a child who was autistic. I was confused because I mistook her description as "artistic." In April 2001, our first child, Isaiah, was born. My wife, Lanier, was concerned that he had autism at about 11 months of age, but I did not recognize his obvious problems, even though he was not responding to his name, was obsessed with spinning objects, and did not play with toys appropriately. He also had no language, did not walk until 18 months, and had significant gastrointestinal (GI) problems including severe reflux requiring medication and chronic diarrhea. At 19 months of age, Isaiah was diagnosed with autistic disorder.

From Baltic rooms to conference rooms: my jouney with data

Science.gov (United States)

Kozlowski, W. A.

2015-12-01

From time spent in murky, mosquito-filled mangrove swamps searching for fiddler crabs, to being transported off ships in webbed "man-baskets" on inky-black winter mornings to sample sea ice, to teaching rooms full of students the benefits of information organization, the wonders of science have long shaped my career path. Regardless of surroundings, the driving factor has always been a desire to learn new skills, then try to figure out how to use them to make work easier or more efficient for myself and hopefully others. Somewhere along the way, I've switched from doing it primarily for my "own" research projects, to a focus on helping others with theirs. Like many in this field, my route to a career in data science has influenced how I do my work. Along the way I've carried skills with me but also learned a few things that have made my journey both practical and fun. In this presentation, I'll discuss a few key factors that contribute to my current efforts as a data curation specialist in a research library, including communication (translation of "library" concepts to "science" concepts and vice versa), flexibility (ability to accomodate ideas, pace and values of those I'm working with), and prioritization (learning to balance what's valuable to researchers with principles important to libraries, curators, repositories, archives and other groups with which I interact).

a bibliometric study

African Journals Online (AJOL)

Nneka Umera-Okeke

50603, Kuala Lumpur, Malaysia. E-mail: murtala@siswa.um.edu.my. Phone: + ... increased trade and investments boosting the roles of private businesses in wealth creation than that of the state. ... It is significant in determining most recent research development on trade liberalisation and to guide other scholars on how to ...

Activation of Toll-like receptors nucleates assembly of the MyDDosome signaling hub.

Science.gov (United States)

Latty, Sarah Louise; Sakai, Jiro; Hopkins, Lee; Verstak, Brett; Paramo, Teresa; Berglund, Nils A; Cammorota, Eugenia; Cicuta, Pietro; Gay, Nicholas J; Bond, Peter J; Klenerman, David; Bryant, Clare E

2018-01-24

Infection and tissue damage induces assembly of supramolecular organizing centres (SMOCs)), such as the Toll-like receptor (TLR) MyDDosome, to co-ordinate inflammatory signaling. SMOC assembly is thought to drive digital all-or-none responses, yet TLR activation by diverse microbes induces anything from mild to severe inflammation. Using single-molecule imaging of TLR4-MyDDosome signaling in living macrophages, we find that MyDDosomes assemble within minutes of TLR4 stimulation. TLR4/MD2 activation leads only to formation of TLR4/MD2 heterotetramers, but not oligomers, suggesting a stoichiometric mismatch between activated receptors and MyDDosomes. The strength of TLR4 signalling depends not only on the number and size of MyDDosomes formed but also how quickly these structures assemble. Activated TLR4, therefore, acts transiently nucleating assembly of MyDDosomes, a process that is uncoupled from receptor activation. These data explain how the oncogenic mutation of MyD88 (L265P) assembles MyDDosomes in the absence of receptor activation to cause constitutive activation of pro-survival NF-κB signalling. © 2018, Latty et al.

Comprendiendo la aparición de los protocolos sociales en MySpace: impacto y ramificaciones Understanding the Emergence of Social Protocols on MySpace: Impact and its Ramifications

Directory of Open Access Journals (Sweden)

Hiesun Cecilia Suhr

2010-03-01

Full Text Available En los últimos años, MySpace ha sido crucial para promover el aumento de los seguidores de músicos independientes y ha representado un papel muy importante a la hora de ayudar a artistas populares a mantener las comunidades de fans. La popularidad de MySpace ha ido acompañada del establecimiento de protocolos sociales que han permitido a los músicos establecer vínculos entre ellos de una manera eficaz y exitosa. Estos protocolos han servido de inspiración para publicar varios libros (como «MySpace Music Profit Monster!: Proven Online Marketing Strategies!» de Nicky Kalliongis con consejos y estrategias para los músicos. Si bien, algunos de estos protocolos pretenden conocer el aspecto tecnológico de MySpace, otros protocolos están directamente relacionados con el aprendizaje de una manera particular de conexión en red a través de MySpace. Además, estas prácticas son consideradas un trabajo serio, ya que requieren mucho tiempo y habilidades de conexión en red para lograr un cierto nivel de éxito, es decir, aumentar el número de amigos en la red personal. Así que, en este artículo, se analizan los protocolos sociales emergentes en MySpace como una forma de trabajo afectivo e inmaterial. La autora sostiene que la implementación de algunos consejos, como los proporcionados por expertos en MySpace, posiblemente pueda tener un efecto regresivo en las prácticas de los músicos en redes sociales, ya que podrían estandarizarizarse y volverse repetitivas. En conjunto, este artículo describe la evolución de My - Space, sobre todo en lo que respecta a la decreciente popularidad del sitio como una tendencia actual.Over the recent years, MySpace has been vital to fostering the growth of independent musicians’ followings and have played critical roles in helping mainstream artists maintain fan communities. The popularity of MySpace has been accompanied by the establishment of social protocols which allow musicians to network with

Reflections from my Pedagogical Practice: Spontaneity versus Formalization

Directory of Open Access Journals (Sweden)

Carla Brenes-Jiménez

2015-01-01

Full Text Available This article describes an action research process undertaken with the main purpose of recognizing, re-evaluating and revising my pedagogical practices, together with the children I work with (two preschool groups: the first one is a preschool group I interacted with in 2012 comprised of 6 students ages 2 years and 3 months to 3 years and 3 months, while the second one is a group of 13 K-students ages 4 years and 3 months to 5 years and 3 months, with whom I shared in 2013.  This research process reflects the changes that drove me to a metamorphosis. In this process, evidence is given of findings, lessons learned and lessons unlearned which arose from the use of methodological strategies drawn from the naturalist paradigm. As part of the action research process, a change can be noted in my performance where I pass from a vertical epistemological position, in which my practices focused on memory, order and repetition, to a horizontal one in which children have the possibility of engaging in dialog, freely creating and sharing. The main tools to compile the information were filming and the classes shared with my students.

Braid My Hair - Randy Owen sings out for sick children

Science.gov (United States)

... Issue Past Issues Braid My Hair - Randy Owen sings out for sick children Past Issues / Spring 2008 ... to it. Former Alabama lead singer Randy Owen sings his new song, "Braid My Hair." Photo courtesy ...

Why Is It Important to Know My Family Medical History?

Science.gov (United States)

... know my family medical history? Why is it important to know my family medical history? A family ... for Links Data Files & API Site Map Subscribe Customer Support USA.gov Copyright Privacy Accessibility FOIA Viewers & ...

National data centre preparedness exercise 2015 (NPE2015): MY-NDC progress result and experience

Science.gov (United States)

Rashid, Faisal Izwan Abdul; Zolkaffly, Muhammed Zulfakar

2017-01-01

Malaysia has established the National Data Centre (MY-NDC) in December 2005. MY-NDC is tasked to perform the Comprehensive Nuclear-Test-Ban-Treaty (CTBT) data management as well as providing relevant information for Treaty related events to the Malaysian Nuclear Agency (Nuclear Malaysia) as the CTBT National Authority. In the late 2015, MY-NDC has participated in the National Data Centre Preparedness Exercise 2015 (NPE 2015) which aims to access the level of readiness at MY-NDC. This paper aims at presenting the progress result of NPE 2015 as well as highlighting MY-NDC experience in NPE 2015 compared to previous participation in NPE 2013. MY-NDC has utilised available resources for NPE 2015. In NPE 2015, MY-NDC has performed five type of analyses compared with only two analyses in NPE 2013. Participation in the NPE 2015 has enabled MY-NDC to assess its capability and identify rooms for improvement.

41 CFR 301-52.17 - Within how many calendar days after I submit a proper travel claim must my agency reimburse my...

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false Within how many calendar days after I submit a proper travel claim must my agency reimburse my allowable expenses? 301-52.17... REIMBURSEMENT 52-CLAIMING REIMBURSEMENT § 301-52.17 Within how many calendar days after I submit a proper travel...

My-Forensic-Loci-queries (MyFLq) framework for analysis of forensic STR data generated by massive parallel sequencing.

Science.gov (United States)

Van Neste, Christophe; Vandewoestyne, Mado; Van Criekinge, Wim; Deforce, Dieter; Van Nieuwerburgh, Filip

2014-03-01

Forensic scientists are currently investigating how to transition from capillary electrophoresis (CE) to massive parallel sequencing (MPS) for analysis of forensic DNA profiles. MPS offers several advantages over CE such as virtually unlimited multiplexy of loci, combining both short tandem repeat (STR) and single nucleotide polymorphism (SNP) loci, small amplicons without constraints of size separation, more discrimination power, deep mixture resolution and sample multiplexing. We present our bioinformatic framework My-Forensic-Loci-queries (MyFLq) for analysis of MPS forensic data. For allele calling, the framework uses a MySQL reference allele database with automatically determined regions of interest (ROIs) by a generic maximal flanking algorithm which makes it possible to use any STR or SNP forensic locus. Python scripts were designed to automatically make allele calls starting from raw MPS data. We also present a method to assess the usefulness and overall performance of a forensic locus with respect to MPS, as well as methods to estimate whether an unknown allele, which sequence is not present in the MySQL database, is in fact a new allele or a sequencing error. The MyFLq framework was applied to an Illumina MiSeq dataset of a forensic Illumina amplicon library, generated from multilocus STR polymerase chain reaction (PCR) on both single contributor samples and multiple person DNA mixtures. Although the multilocus PCR was not yet optimized for MPS in terms of amplicon length or locus selection, the results show excellent results for most loci. The results show a high signal-to-noise ratio, correct allele calls, and a low limit of detection for minor DNA contributors in mixed DNA samples. Technically, forensic MPS affords great promise for routine implementation in forensic genomics. The method is also applicable to adjacent disciplines such as molecular autopsy in legal medicine and in mitochondrial DNA research. Copyright © 2013 The Authors. Published by

My Changing Perception of Mars: A Whipple Award Lecture

Science.gov (United States)

Malin, M. C.

2017-12-01

I have been studying Mars for 46+ years. My initial studies of the planet were mentored by Bruce Murray (my Ph.D. advisor) and Bob Sharp. My 4 years as Bruce's student were the most productive and exciting of my early career, during which I wrote or participated in a dozen published works. My early efforts on Mars, based on Mariner 9 images, culminated in my Ph.D. dissertation, the last paragraph of which, written in 1975, read: "In summary, Mars appears to have had a complex early history, complete with significant atmospheric and some fluid erosion. Just as the polar layered deposits are believed to record the recent history of Mars, so may the ancient layered deposits — the intercrater plains — record the most primitive history of Mars. Detailed studies of Martian stratigraphy in the distant future may be as intellectually rewarding as the studies of terrestrial stratigraphy are today."Welcome to the distant future! During my student years with Murray and Sharp, I concluded that images of significantly higher spatial resolution were needed to unravel the geologic story hinted at in the Mariner 9 data. For 10 years I made the case for aerial photo-like high resolution imaging, to highly skeptical science and engineering communities. With Ed Danielson (of JPL and then Caltech) and a group of young engineers he recruited, we succeeded in convincing advisory groups and a NASA selection board to fly the Mars Observer Camera, that included early 1980's innovations such as a 32-bit microprocessor, a 100 MB solid state memory, gate arrays for instrument control, and a 35 cm aperture telescope with an f/2 primary and a secondary mirror with 8-fold magnification to achieve 3.7 µrad/pixel scale (1.4 m/pxl from 378 km altitude). Although MO failed, the MOC was reflown on MGS and my colleague Ken Edgett and I found evidence for: widespread water-lain sedimentary rock, persistent surficial water flow and ponding in bodies of standing water, gullies that may indicate the

On my association with Bell Labs

Science.gov (United States)

Sondhi, M. Mohan

2004-05-01

I joined the Acoustics Research department at Bell Labs in 1962, just eight days before AT&T launched the first communications satellite, Telstar. During the 39 years between 1962 and my retirement in 2001, I worked on several problems related in one way or another to the processing of speech signals. Schroeder and Flanagan are presenting talks from a broad perspective in this session, so I will confine this talk to just my own contributions and collaborations for some of the topics on which I worked, e.g., echo cancellation, inverse problems in acoustics, speech analysis, synthesis, and recognition. I will tell you about one of these contributions that fortunately turned out to yield considerable profits to AT&T. To give you a flavor of the spirit of free inquiry at Bell Labs during that period, I will tell you about the contribution that I am most proud of (which was supported for several years even though it had no monetary value). And I will also mention the contribution that is most often cited of all my papers (which was in collaboration with two mathematicians, and had nothing at all to do with acoustics).

My tryst with the monsoon

Indian Academy of Sciences (India)

Lawrence

approach for my undergraduate studies at Fergusson College, back in Pune. Madhav, the fellow student whom I eventually married, claims that I ... ics at Pune University. ... complexity to understand the mechanisms responsible for impor-.

PHP & MySQL The Missing Manual

CERN Document Server

McLaughlin, Brett

2011-01-01

If you can build websites with CSS and JavaScript, this book takes you to the next level-creating dynamic, database-driven websites with PHP and MySQL. Learn how to build a database, manage your content, and interact with users through queries and web forms. With step-by-step tutorials, real-world examples, and jargon-free explanations, you'll soon discover the power of server-side programming. The important stuff you need to know: Get a running start. Write PHP scripts and create a web form right away.Learn the language. Get up to speed on PHP and SQL syntax quickly.Build a database. Use My

PHP and MySQL for Dummies

CERN Document Server

Valade, Janet

2009-01-01

Here's what Web designers need to know to create dynamic, database-driven Web sites. To be on the cutting edge, Web sites need to serve up HTML, CSS, and products specific to the needs of different customers using different browsers. An effective e-commerce site gathers information about users and provides information they need to get the desired result. PHP scripting language with a MySQL back-end database offers an effective way to design sites that meet these requirements. This full updated 4th Edition of PHP & MySQL For Dummies gets you quickly up to speed, even if your experience is limit

Shelf-life evaluation of bilayered human skin equivalent, MyDerm™.

Directory of Open Access Journals (Sweden)

Wan Tai Seet

Full Text Available Skin plays an important role in defense against infection and other harmful biological agents. Due to its fragile structure, skin can be easily damaged by heat, chemicals, traumatic injuries and diseases. An autologous bilayered human skin equivalent, MyDerm™, was engineered to provide a living skin substitute to treat critical skin loss. However, one of the disadvantages of living skin substitute is its short shelf-life, hence limiting its distribution worldwide. The aim of this study was to evaluate the shelf-life of MyDerm™ through assessment of cell morphology, cell viability, population doubling time and functional gene expression levels before transplantation. Skin samples were digested with 0.6% Collagenase Type I followed by epithelial cells dissociation with TrypLE Select. Dermal fibroblasts and keratinocytes were culture-expanded to obtain sufficient cells for MyDerm™ construction. MyDerm™ was constructed with plasma-fibrin as temporary biomaterial and evaluated at 0, 24, 48 and 72 hours after storage at 4°C for its shelf-life determination. The morphology of skin cells derived from MyDerm™ remained unchanged across storage times. Cells harvested from MyDerm™ after storage appeared in good viability (90.5%±2.7% to 94.9%±1.6% and had short population doubling time (58.4±8.7 to 76.9±19 hours. The modest drop in cell viability and increased in population doubling time at longer storage duration did not demonstrate a significant difference. Gene expression for CK10, CK14 and COL III were also comparable between different storage times. In conclusion, MyDerm™ can be stored in basal medium at 4°C for at least 72 hours before transplantation without compromising its functionality.

Shelf-life evaluation of bilayered human skin equivalent, MyDerm™.

Science.gov (United States)

Seet, Wan Tai; Manira, Maarof; Maarof, Manira; Khairul Anuar, Khairoji; Chua, Kien-Hui; Ahmad Irfan, Abdul Wahab; Ng, Min Hwei; Aminuddin, Bin Saim; Ruszymah, Bt Hj Idrus

2012-01-01

Skin plays an important role in defense against infection and other harmful biological agents. Due to its fragile structure, skin can be easily damaged by heat, chemicals, traumatic injuries and diseases. An autologous bilayered human skin equivalent, MyDerm™, was engineered to provide a living skin substitute to treat critical skin loss. However, one of the disadvantages of living skin substitute is its short shelf-life, hence limiting its distribution worldwide. The aim of this study was to evaluate the shelf-life of MyDerm™ through assessment of cell morphology, cell viability, population doubling time and functional gene expression levels before transplantation. Skin samples were digested with 0.6% Collagenase Type I followed by epithelial cells dissociation with TrypLE Select. Dermal fibroblasts and keratinocytes were culture-expanded to obtain sufficient cells for MyDerm™ construction. MyDerm™ was constructed with plasma-fibrin as temporary biomaterial and evaluated at 0, 24, 48 and 72 hours after storage at 4°C for its shelf-life determination. The morphology of skin cells derived from MyDerm™ remained unchanged across storage times. Cells harvested from MyDerm™ after storage appeared in good viability (90.5%±2.7% to 94.9%±1.6%) and had short population doubling time (58.4±8.7 to 76.9±19 hours). The modest drop in cell viability and increased in population doubling time at longer storage duration did not demonstrate a significant difference. Gene expression for CK10, CK14 and COL III were also comparable between different storage times. In conclusion, MyDerm™ can be stored in basal medium at 4°C for at least 72 hours before transplantation without compromising its functionality.

Comparison of Regenerative Braking Efficiencies of MY2012 and MY2013 Nissan Leaf

Directory of Open Access Journals (Sweden)

Albert Boretti

2016-07-01

Full Text Available The use of kinetic energy recovery systems (KERS is the best solution presently available to dramatically improve the energy economy of passenger cars. The paper presents an experimental analysis of the energy flow to and from the battery of a MY 2012 and a MY 2013 Nissan Leaf covering the Urban Dynamometer Driving Schedule (UDDS. The two vehicles differ for the integration of the electric drivetrain component, plus a different use of the electric motor and the regenerative brakes, in addition to a different weight. It is shown that while the efficiency propulsive power to vehicle / power from battery are basically unchanged, at about 87-89 %, the efficiency power to the battery / braking power to vehicle are significantly improved from values of about 70-80 % to values of 72-87 %. The analysis provides a state-of-the-art benchmark of the propulsion and regenerative braking efficiencies of electric vehicles.

INIS in My Life

International Nuclear Information System (INIS)

Tolstenkov, Anatoly

2015-01-01

The first time I learned about INIS was in 1975, when I began my career as a junior researcher at the Institute for High Energy Physics (IHEP). At that time, I could not imagine that my future life would be so closely linked to this unique system. Having begun scientific work at IHEP, I faced a serious problem of lack of access to foreign nuclear information that was a vital prerequisite for any scientific activity. At the time, there were only 3 main ways to access foreign information: the use of the Russian information system Referativnyi Zhurnal; a subscription to the leading nuclear journals such as Physical Review and Nuclear Physics; and direct personal contacts, mainly at international conferences. This was obviously insufficient, and access to pre-prints and reports was necessary, considering that at that time there was a significant time lag in published journal articles. Receiving the first magnetic tape with INIS records was a momentous occasion for scientists at my Institute. The first use of INIS information demonstrated the many innovative ideas and thoughts used to develop INIS. Obviously, at that time, there was no other nuclear information system that could compete with INIS on completeness of coverage, the volume of the information, and on the number of people involved in data collection and processing. Even now, I continue to be amazed that from the first day of operations, INIS started collecting NCL documents. As a result, the INIS NCL archive, with over 700 000 documents, was created and many of the documents from the NCL archive remain relevant to modern nuclear research

40 CFR 63.11094 - What are my recordkeeping requirements?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 14 2010-07-01 2010-07-01 false What are my recordkeeping requirements....11094 What are my recordkeeping requirements? (a) Each owner or operator of a bulk gasoline terminal or... compliance with paragraph (c)(1) of this section. (2) For facilities that use a terminal automation system to...

Comparison Of Perceived Students Competency Between Industrial And University

Directory of Open Access Journals (Sweden)

Noor Azland Jainudin

2015-08-01

Full Text Available In Malaysia engineering programs in the public universities require the approval of the Ministry of Higher Education MOHE and accreditation by the Malaysian Qualification Agency MQA. However not all the engineering programs are designed with the industrial training component. Recently in order to enhance employability of the graduates industrial training course was introduced as one of the compulsory requirements in the diploma program of Faculty of Civil Engineering Universiti Teknologi MARA UiTM. The objective of the training is to expose UiTM students to the competency knowledge and skills needed to succeed at the workplace. Based on comparison studied it was found that higher graded was given by the supervisor from university compared to supervisor from industrial. Supervisor from university faculty knew well practical student rather than supervisor from industrial training for a longer period of time which attributed to high mean score.

A is for aphorism--'medicine is my lawful wife, and literature is my mistress. When I get [fed up with] one, I spend the night with the other.'.

Science.gov (United States)

Koh, Chee

2013-09-01

'I feel more confident and more satisfied with myself when I reflect that I have two professions and not one. Medicine is my lawful wife, and literature is my mistress. When I get tired of one I spend the night with the other. Though it is irregular, it is less boring this way, and besides, neither of them loses anything through my infidelity.'

The Basics of the Methodological/mo dal professional improvements of the physical/ sports edu ca tors from the aspect of ther actual values of life and professio nal pedagogical activity

Directory of Open Access Journals (Sweden)

Grujo Bjeković

2007-05-01

Full Text Available Whi le sol ving in cre a sed le vel of pro fes si o nal pre pa ra tion of the physi cal edu cation te ac hers, in mo dern days in cre a sed at ten tion is gi ven to in tel lec tual, mo ral, cul tu ral an pro fes si o nal in cre a se of the cre a ti ve un de pen da bi lity of the fu tu re spe ci a lists with the aim to cre a te shift from pre sently do mi nant physi cal edu ca tion, which is pri ma rily orien ted to wards the de ve lop ment of the physi cal ca pa bi li ti es for ming the per fect mo ving abi li ti es and ha bits, to de ve lop ment of the who le hu man be ing The lead ro le of the se tasks be longs to the ac me o logy, a mul ti di sci pli nary sci en ce abo ut a hu man and so ci ety. In this pa per, a ba sic ca te go rial ap pa ra tus of ac me o logy has bean de fi ned, ac cording to the le vel of it’s mo dern de ve lop ment, co ve ring pro fes si o na lism and com pe tency. To re ach de fi ned goal the fol lo wing sci en ti fi c met hods ha ve been used: analysis of met hodo lo gi cal li te ra tu re, qu e sti on na i re and mo de ling. Twenty pro fes sors of the physi cal edu ca tion with up to 10 year s and mo re as well as 20 stu dents of the Physi cal edu ca tion fa culty from the third and forth year of study ha ve been qu e sti o ned.

Learning Math With My Father: A Memoir

Directory of Open Access Journals (Sweden)

Yolanda De La CRUZ

2012-07-01

Full Text Available If he is indeed wise he does not bid you enter the house of his wisdom, but rather leads you to the threshold of your own mind. Kahlil Gibran. We all build our own houses of wisdom, each of us; we cannot build them for each other. Teachers cannot simply invite students into their houses of wisdom, but can often find ways to help learners to enter and explore their own minds. While Constructivism has had a positive impact on the teaching and learning of literacy mathematics instruction continues to rely heavily on rote memorization and drills. As a young child, I learned to love math. My love of math stems from learning math with my father. He did not focus on rote memorization and drills. The primary emphasis was for a real purpose. My self-confidence was enforced when he started me out with problems that were less difficult and had many different solutions. These solutions were valued and respected, which allowed me to trust in my own problem solving abilities. How can we hope to lead children to the thresholds of their own minds when we remain intent on forcing them into our houses of wisdom? What alternative ways can we devise of interacting with children that respect their confidence and leave intact their levels of understanding, that lead them to the thresholds of their own minds excited about entering?

“There should be a room for self-initiated activity” A narrative inquiry on my teaching practices

Directory of Open Access Journals (Sweden)

Hanung Triyoko

2016-07-01

Full Text Available This paper is my endeavour to shorten the gap between the realities in my own teaching practices and those practices presented in books and research reports as effective English teaching. In this paper, through narrative inquiry method of writing, I will refer to my experiences to show my way of knowing as well as my way of writing the specific contexts of my teaching of English. Here and then, I may show my subjectivity upon certain issues in the English teaching-learning process but I do this to enable myself go deeper to my personal values. Nonetheless, for the betterment of my classroom practices specifically and the teaching of English for Islamic studies in Indonesia, in general, my inquiry on my own professional practices and the insights on how I should see and make some changes in my teaching as specified by the AAA perspective discussed in details will become a very good start.

The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer.

LENUS (Irish Health Repository)

d'Adhemar, Charles J

2014-01-01

The prognosis of epithelial ovarian cancer is poor in part due to the high frequency of chemoresistance. Recent evidence points to the Toll-like receptor-4 (TLR4), and particularly its adaptor protein MyD88, as one potential mediator of this resistance. This study aims to provide further evidence that MyD88 positive cancer cells are clinically significant, stem-like and reproducibly detectable for the purposes of prognostic stratification. Expression of TLR4 and MyD88 was assessed immunohistochemically in 198 paraffin-embedded ovarian tissues and in an embryonal carcinoma model of cancer stemness. In parallel, expression of TLR4 and MyD88 mRNA and regulatory microRNAs (miR-21 and miR-146a) was assessed, as well as in a series of chemosensitive and resistant cancer cells lines. Functional analysis of the pathway was assessed in chemoresistant SKOV-3 ovarian cancer cells. TLR4 and MyD88 expression can be reproducibly assessed via immunohistochemistry using a semi-quantitative scoring system. TLR4 expression was present in all ovarian epithelium (normal and neoplastic), whereas MyD88 was restricted to neoplastic cells, independent of tumour grade and associated with reduced progression-free and overall survival, in an immunohistological specific subset of serous carcinomas, p<0.05. MiR-21 and miR-146a expression was significantly increased in MyD88 negative cancers (p<0.05), indicating their participation in regulation. Significant alterations in MyD88 mRNA expression were observed between chemosensitive and chemoresistant cells and tissue. Knockdown of TLR4 in SKOV-3 ovarian cells recovered chemosensitivity. Knockdown of MyD88 alone did not. MyD88 expression was down-regulated in differentiated embryonal carcinoma (NTera2) cells, supporting the MyD88+ cancer stem cell hypothesis. Our findings demonstrate that expression of MyD88 is associated with significantly reduced patient survival and altered microRNA levels and suggest an intact\\/functioning TLR4\\/MyD88

The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer.

Directory of Open Access Journals (Sweden)

Charles J d'Adhemar

Full Text Available The prognosis of epithelial ovarian cancer is poor in part due to the high frequency of chemoresistance. Recent evidence points to the Toll-like receptor-4 (TLR4, and particularly its adaptor protein MyD88, as one potential mediator of this resistance. This study aims to provide further evidence that MyD88 positive cancer cells are clinically significant, stem-like and reproducibly detectable for the purposes of prognostic stratification. Expression of TLR4 and MyD88 was assessed immunohistochemically in 198 paraffin-embedded ovarian tissues and in an embryonal carcinoma model of cancer stemness. In parallel, expression of TLR4 and MyD88 mRNA and regulatory microRNAs (miR-21 and miR-146a was assessed, as well as in a series of chemosensitive and resistant cancer cells lines. Functional analysis of the pathway was assessed in chemoresistant SKOV-3 ovarian cancer cells. TLR4 and MyD88 expression can be reproducibly assessed via immunohistochemistry using a semi-quantitative scoring system. TLR4 expression was present in all ovarian epithelium (normal and neoplastic, whereas MyD88 was restricted to neoplastic cells, independent of tumour grade and associated with reduced progression-free and overall survival, in an immunohistological specific subset of serous carcinomas, p<0.05. MiR-21 and miR-146a expression was significantly increased in MyD88 negative cancers (p<0.05, indicating their participation in regulation. Significant alterations in MyD88 mRNA expression were observed between chemosensitive and chemoresistant cells and tissue. Knockdown of TLR4 in SKOV-3 ovarian cells recovered chemosensitivity. Knockdown of MyD88 alone did not. MyD88 expression was down-regulated in differentiated embryonal carcinoma (NTera2 cells, supporting the MyD88+ cancer stem cell hypothesis. Our findings demonstrate that expression of MyD88 is associated with significantly reduced patient survival and altered microRNA levels and suggest an intact/functioning TLR4

Make My Trip Count 2015

Data.gov (United States)

Allegheny County / City of Pittsburgh / Western PA Regional Data Center — The Make My Trip Count (MMTC) commuter survey, conducted in September and October 2015 by GBA, the Pittsburgh 2030 District, and 10 other regional transportation...

My Most Memorable AAS Meeting-December 1957, Butler University, Indianapolis, Indiana

Science.gov (United States)

Edmondson, F. K.

1999-05-01

My attendance at AAS meetings began with the 46th meeting in September 1931 at the brand new Perkins Observatory. This was the first semester of my junior year at Indiana University. Professor Wilbur Cogshall, my astronomy professor, took me to the meeting, and paid my expenses for dormitory accommodations and meals. Hence, my attendance at AAS meetings covers a span of nearly 68 years. There have been so many "memorable" meetings that it is hard to pick just one. However, the 99th meeting in December 1957 at Butler University in Indianapolis, a joint meeting with the AAAS, is memorable because I was in a wheel chair and using crutches, following an injury to my right knee cap. I was a member of the AAAS Committee to select the "best paper" presented at the meeting to receive the Newcomb Cleveland Prize, and Martin Schwarzschild's first report of results from Project Stratoscope was on the program. I showed up at the Committee meeting in my wheel chair, and nominated Martin's paper for the "best paper" award. The Committee asked a lot of questions and then approved the paper by a unanimous vote. The wheel chair and crutches obviously played a role in convincing the Committee that I had strong feelings about the merits of Martin's paper. Allan Sandage was the Warner Prize Lecturer, and reported on the current status of his revision of the cosmic distance scale. Hubble's 1936 distances needed to be increased by a factor of five to ten.

30 CFR 285.906 - What must my decommissioning application include?

Science.gov (United States)

2010-07-01

... OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Decommissioning Decommissioning Applications § 285.906 What must my decommissioning application include? You must... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must my decommissioning application...

PathScore: a web tool for identifying altered pathways in cancer data.

Science.gov (United States)

Gaffney, Stephen G; Townsend, Jeffrey P

2016-12-01

PathScore quantifies the level of enrichment of somatic mutations within curated pathways, applying a novel approach that identifies pathways enriched across patients. The application provides several user-friendly, interactive graphic interfaces for data exploration, including tools for comparing pathway effect sizes, significance, gene-set overlap and enrichment differences between projects. Web application available at pathscore.publichealth.yale.edu. Site implemented in Python and MySQL, with all major browsers supported. Source code available at: github.com/sggaffney/pathscore with a GPLv3 license. stephen.gaffney@yale.edu. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Die Entwicklungsgeschichte von MyCoRe an der Universität Leipzig

Directory of Open Access Journals (Sweden)

Jens Kupferschmidt

2018-04-01

Full Text Available This article is a short overview on the history and functionality of the MyCoRe project, which is currently developed by various German universities. The MyCoRe-based applications can be used for cataloging and presentation of digitalized objects like papyrus, manuscripts and antique books. MyCoRe is also able to produce different kinds of repository servers.

41 CFR 302-9.204 - What is the “authorized point of origin” when I transport my POV from my post of duty?

Science.gov (United States)

2010-07-01

... point of originâ when I transport my POV from my post of duty? 302-9.204 Section 302-9.204 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES TRANSPORTATION AND... Return Transportation of a POV From a Post of Duty § 302-9.204 What is the “authorized point of origin...

MySQL High Availability Tools for Building Robust Data Centers

CERN Document Server

Bell, Charles; Thalmann, Lars

2010-01-01

Server bottlenecks and failures are a fact of life in any database deployment, but they don't have to bring everything to a halt. MySQL has several features that can help you protect your system from outages, whether it's running on hardware, virtual machines, or in the cloud. MySQL High Availability explains how to use these replication, cluster, and monitoring features in a wide range of real-life situations. Written by engineers who designed many of the tools covered inside, this book reveals undocumented or hard-to-find aspects of MySQL reliability and high availability -- knowledge that

Help My House Program Profile

Science.gov (United States)

Learn about Help My House, a program that helps participants reduce their utility bills by nearly 35 percent through low-cost loans for EE improvements. Learn more about the key features, approaches, funding sources, and achievements of this program.

National Data Center Preparedness Exercise 2015 (NPE 2015): MY-NDC Preliminary Analysis Result

International Nuclear Information System (INIS)

Faisal Izwan Abdul Rashid; Muhammed Zulfakar Zolkaffly

2016-01-01

Malaysia has established the CTBT National Data Centre (MY-NDC) in December 2005. MY-NDC is tasked to perform Comprehensive Nuclear-Test-Ban-Treaty (CTBT) data management as well as provide information for Treaty related events to Nuclear Malaysia as CTBT National Authority. In 2015, MY-NDC has participated in the National Data Centre Preparedness Exercise 2015 (NPE 2015). This paper aims at presenting MY-NDC preliminary analysis result of NPE 2015. In NPE 2015, MY-NDC has performed five different analyses, namely, radionuclide, atmospheric transport modelling (ATM), data fusion, seismic analysis and site forensics. The preliminary findings show the hypothetical scenario in NPE 2015 most probably is an uncontained event resulted high release of radionuclide to the air. (author)

Is My Child's Appetite Normal?

Science.gov (United States)

Is My Child’s Appetite Normal? Cayla, who is 4 years old, did not finish her lunch. But she is ready to play. Her ... snack for later. That is okay! Your child’s appetite changes. Children do not grow as fast in ...

Performance Evaluation of the MyT4 Technology for Determining ART Eligibility.

Science.gov (United States)

Sitoe, Nádia; Macamo, Rosa; Meggi, Bindiya; Tobaiwa, Ocean; Loquiha, Osvaldo; Bollinger, Timothy; Vojnov, Lara; Jani, Ilesh

2016-01-01

In resource-limited countries, CD4 T-cell (CD4) testing continues to be used for determining antiretroviral therapy (ART) initiation eligibility and opportunistic infection monitoring. To support expanded access to CD4 testing, simple and robust technologies are necessary. We conducted this study to evaluate the performance of a new Point-of-Care (POC) CD4 technology, the MyT4, compared to conventional laboratory CD4 testing. EDTA venous blood from 200 HIV-positive patients was tested in the laboratory using the MyT4 and BD FACSCalibur™. The MyT4 had an r2 of 0.82 and a mean bias of 12.3 cells/μl. The MyT4 had total misclassifications of 14.7% and 8.8% when analyzed using ART eligibility thresholds of 350 and 500 cells/μl, respectively. We conclude that the MyT4 performed well in classifying patients using the current ART initiation eligibility thresholds in Mozambique when compared to the conventional CD4 technology.

Wandering accelerators throughout my life (4)

International Nuclear Information System (INIS)

Nakai, Kozi

2010-01-01

My effort in the last stage of wandering about accelerator was to bridge the gap between nuclear and high-energy physics at the KEK-PS. Since the TRISTAN construction started, the KEK-PS has been opened to nuclear physics users. Among various possibilities, emphasis was placed on the hypernuclear experiments, K-decay experiments, and later, the long-base-line neutrino experiment (K2K), which were successfully carried out. Although the TRISTAN experiment was unable to find the top quark, the CP-test experiments at TRISTAN-II (KEKB) have proven the Kobayashi-Maskawa theory successfully. During the last three years of my tenure in KEK, I served as a science adviser to Minister of Education, and I was involved in international affairs of accelerator science. (author)

30 CFR 285.534 - When may MMS cancel my bond?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When may MMS cancel my bond? 285.534 Section 285.534 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE... Assurance Requirements Changes in Financial Assurance § 285.534 When may MMS cancel my bond? When your lease...

This paper describes 14 Colombian web based “edu-communicational” projects. The aim is to analyze different types of platforms, different type of use and the elements that facilitate interaction with final users. The study sample is composed of three main

Directory of Open Access Journals (Sweden)

Tomás Durán Becerra

2017-12-01

Full Text Available This paper describes 14 Colombian web based “edu-communicational” projects. The aim is to analyze different types of platforms, different type of use and the elements that facilitate interaction with final users. The study sample is composed of three main categories of sites: formal education sites, informal education sites and other types of sites that contain some kind of educational content. The research establishes different variables aimed at discovering educommunicative tools. Both the theoretical framework and the conceptual approach to edu-communication, as well as the methodological proposal applied are retrieved from the works of De Oliveira (2009, Freire (2002, Barbas Coslado (2012, Pérez-Tornero (2004, Tejedor (2010, Said and Arcila (2011a and O’Reilly (2009, among others. In conclusion, the article shows similarities and differences among the platforms that shape the online edu-communicational landscape in Colombia.

Significance of TLR4/MyD88 expression in breast cancer

Science.gov (United States)

Chen, Xiangjin; Zhao, Feng; Zhang, Huihao; Zhu, Youzhi; Wu, Kunlin; Tan, Guozheng

2015-01-01

Objective: To investigate the expression of TLR4/MyD88 in breast cancer, and explore the relationship between their expression and breast cancer tumor growth and invasion. Methods: We examined the protein expression of TLR4 and MyD88 in 60 cases of histologically confirmed breast cancer. The relationship of their protein expressions with clinical features including age at diagnosis, tumor size and stage, lymph node metastasis and distant metastasis were analyzed. Results: The IHC results showed that TLR4 and MyD88 were expressed in 63.3% (38/60) and 58.3% (35/60) of malignant breast tumors respectively. TLR4 expression in breast cancer were significantly higher than in fibroadenoma (n = 4, 20.0%) and adjacent normal tissues (n = 2, 10.0%) (P fibroadenoma (n = 4, 20.0%) and adjacent normal tissue (n = 3, 15.0%) (P fibroadenoma and adjacent normal tissues (P < 0.05). The protein expressions of TLR4 and MyD88 were also significantly associated with poor clinical features (P < 0.05). Conclusion: TLR4 and MyD88 expression might be associated with breast cancer growth and regional and distant metastases. PMID:26261595

Petaminer: Using ROOT for efficient data storage in MySQL database

Science.gov (United States)

Cranshaw, J.; Malon, D.; Vaniachine, A.; Fine, V.; Lauret, J.; Hamill, P.

2010-04-01

High Energy and Nuclear Physics (HENP) experiments store Petabytes of event data and Terabytes of calibration data in ROOT files. The Petaminer project is developing a custom MySQL storage engine to enable the MySQL query processor to directly access experimental data stored in ROOT files. Our project is addressing the problem of efficient navigation to PetaBytes of HENP experimental data described with event-level TAG metadata, which is required by data intensive physics communities such as the LHC and RHIC experiments. Physicists need to be able to compose a metadata query and rapidly retrieve the set of matching events, where improved efficiency will facilitate the discovery process by permitting rapid iterations of data evaluation and retrieval. Our custom MySQL storage engine enables the MySQL query processor to directly access TAG data stored in ROOT TTrees. As ROOT TTrees are column-oriented, reading them directly provides improved performance over traditional row-oriented TAG databases. Leveraging the flexible and powerful SQL query language to access data stored in ROOT TTrees, the Petaminer approach enables rich MySQL index-building capabilities for further performance optimization.

Petaminer: Using ROOT for efficient data storage in MySQL database

International Nuclear Information System (INIS)

Cranshaw, J; Malon, D; Vaniachine, A; Fine, V; Lauret, J; Hamill, P

2010-01-01

High Energy and Nuclear Physics (HENP) experiments store Petabytes of event data and Terabytes of calibration data in ROOT files. The Petaminer project is developing a custom MySQL storage engine to enable the MySQL query processor to directly access experimental data stored in ROOT files. Our project is addressing the problem of efficient navigation to PetaBytes of HENP experimental data described with event-level TAG metadata, which is required by data intensive physics communities such as the LHC and RHIC experiments. Physicists need to be able to compose a metadata query and rapidly retrieve the set of matching events, where improved efficiency will facilitate the discovery process by permitting rapid iterations of data evaluation and retrieval. Our custom MySQL storage engine enables the MySQL query processor to directly access TAG data stored in ROOT TTrees. As ROOT TTrees are column-oriented, reading them directly provides improved performance over traditional row-oriented TAG databases. Leveraging the flexible and powerful SQL query language to access data stored in ROOT TTrees, the Petaminer approach enables rich MySQL index-building capabilities for further performance optimization.

My Personal Journey With Ovarian Cancer Treatment: Caring and Chemotherapy Tips.

Science.gov (United States)

Decker, Kim A

2016-12-01

Six years ago, I was diagnosed with stage IIIA ovarian low malignant cell potential cancer. It was the most shocking situation I have ever experienced. I didn't realize I had any symptoms, except occasional back pain, which I attributed to starting a new workout program. I had scheduled an abdominal computerized tomography (CT) scan for recurrent microscopic hematuria, which my internist wanted to check. I was told I would hear the results in two days. Two hours after my CT scan, while I was eating ice cream and watching television, an on-call genitourinary doctor (who I did not personally know) called to tell me the good news-that I had kidney stones, thus the microscopic hematuria. However, the bad news was that I had ovarian cancer that had spread to my omentum. He said he would call my gynecologist right away.

Development of MY-DRG casemix pharmacy service weights in UKM Medical Centre in Malaysia.

Science.gov (United States)

Ali Jadoo, Saad Ahmed; Aljunid, Syed Mohamed; Nur, Amrizal Muhammad; Ahmed, Zafar; Van Dort, Dexter

2015-02-10

The service weight is among several issues and challenges in the implementation of case-mix in developing countries, including Malaysia. The aim of this study is to develop the Malaysian Diagnosis Related Group (MY-DRG) case-mix pharmacy service weight in University Kebangsaan Malaysia-Medical Center (UKMMC) by identifying the actual cost of pharmacy services by MY-DRG groups in the hospital. All patients admitted to UKMMC in 2011 were recruited in this study. Combination of Step-down and Bottom-up costing methodology has been used in this study. The drug and supplies cost; the cost of staff; the overhead cost; and the equipment cost make up the four components of pharmacy. Direct costing approach has been employed to calculate Drugs and supplies cost from electronic-prescription system; and the inpatient pharmacy staff cost, while the overhead cost and the pharmacy equipments cost have been calculated indirectly from MY-DRG data base. The total pharmacy cost was obtained by summing the four pharmacy components' cost per each MY-DRG. The Pharmacy service weight of a MY-DRG was estimated by dividing the average pharmacy cost of the investigated MY-DRG on the average of a specified MY-DRG (which usually the average pharmacy cost of all MY-DRGs). Drugs and supplies were the main component (86.0%) of pharmacy cost compared o overhead cost centers (7.3%), staff cost (6.5%) and pharmacy equipments (0.2%) respectively. Out of 789 inpatient MY-DRGs case-mix groups, 450 (57.0%) groups were utilized by the UKMMC. Pharmacy service weight has been calculated for each of these 450 MY-DRGs groups. MY-DRG case-mix group of Lymphoma & Chronic Leukemia group with severity level three (C-4-11-III) has the highest pharmacy service weight of 11.8 equivalents to average pharmacy cost of RM 5383.90. While the MY-DRG case-mix group for Circumcision with severity level one (V-1-15-I) has the lowest pharmacy service weight of 0.04 equivalents to average pharmacy cost of RM 17.83. A mixed

My career as an immunoglycobiologist.

Science.gov (United States)

Marcus, Donald M

2013-01-01

The research program of my laboratory included three major topics: the structures and immunology of human carbohydrate blood group and glycosphingolipid antigens; the tissue distribution, subcellular localization and biosynthesis of glycosphingolipids; and the structural basis of the binding of carbohydrates by antibodies and lectins.

An online database for informing ecological network models: http://kelpforest.ucsc.edu.

Science.gov (United States)

Beas-Luna, Rodrigo; Novak, Mark; Carr, Mark H; Tinker, Martin T; Black, August; Caselle, Jennifer E; Hoban, Michael; Malone, Dan; Iles, Alison

2014-01-01

Ecological network models and analyses are recognized as valuable tools for understanding the dynamics and resiliency of ecosystems, and for informing ecosystem-based approaches to management. However, few databases exist that can provide the life history, demographic and species interaction information necessary to parameterize ecological network models. Faced with the difficulty of synthesizing the information required to construct models for kelp forest ecosystems along the West Coast of North America, we developed an online database (http://kelpforest.ucsc.edu/) to facilitate the collation and dissemination of such information. Many of the database's attributes are novel yet the structure is applicable and adaptable to other ecosystem modeling efforts. Information for each taxonomic unit includes stage-specific life history, demography, and body-size allometries. Species interactions include trophic, competitive, facilitative, and parasitic forms. Each data entry is temporally and spatially explicit. The online data entry interface allows researchers anywhere to contribute and access information. Quality control is facilitated by attributing each entry to unique contributor identities and source citations. The database has proven useful as an archive of species and ecosystem-specific information in the development of several ecological network models, for informing management actions, and for education purposes (e.g., undergraduate and graduate training). To facilitate adaptation of the database by other researches for other ecosystems, the code and technical details on how to customize this database and apply it to other ecosystems are freely available and located at the following link (https://github.com/kelpforest-cameo/databaseui).

31 CFR 363.14 - How will you verify my identity?

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false How will you verify my identity? 363... you verify my identity? (a) Individual. When you establish an account, we may use a verification service to verify your identity using information you provide about yourself on the online application. At...

Implementation of an interactive database interface utilizing HTML, PHP, JavaScript, and MySQL in support of water quality assessments in the Northeastern North Carolina Pasquotank Watershed

Science.gov (United States)

Guion, A., Jr.; Hodgkins, H.

2015-12-01

The Center of Excellence in Remote Sensing Education and Research (CERSER) has implemented three research projects during the summer Research Experience for Undergraduates (REU) program gathering water quality data for local waterways. The data has been compiled manually utilizing pen and paper and then entered into a spreadsheet. With the spread of electronic devices capable of interacting with databases, the development of an electronic method of entering and manipulating the water quality data was pursued during this project. This project focused on the development of an interactive database to gather, display, and analyze data collected from local waterways. The database and entry form was built in MySQL on a PHP server allowing participants to enter data from anywhere Internet access is available. This project then researched applying this data to the Google Maps site to provide labeling and information to users. The NIA server at http://nia.ecsu.edu is used to host the application for download and for storage of the databases. Water Quality Database Team members included the authors plus Derek Morris Jr., Kathryne Burton and Mr. Jeff Wood as mentor.

MyGeoHub: A Collaborative Geospatial Research and Education Platform

Science.gov (United States)

Kalyanam, R.; Zhao, L.; Biehl, L. L.; Song, C. X.; Merwade, V.; Villoria, N.

2017-12-01

Scientific research is increasingly collaborative and globally distributed; research groups now rely on web-based scientific tools and data management systems to simplify their day-to-day collaborative workflows. However, such tools often lack seamless interfaces, requiring researchers to contend with manual data transfers, annotation and sharing. MyGeoHub is a web platform that supports out-of-the-box, seamless workflows involving data ingestion, metadata extraction, analysis, sharing and publication. MyGeoHub is built on the HUBzero cyberinfrastructure platform and adds general-purpose software building blocks (GABBs), for geospatial data management, visualization and analysis. A data management building block iData, processes geospatial files, extracting metadata for keyword and map-based search while enabling quick previews. iData is pervasive, allowing access through a web interface, scientific tools on MyGeoHub or even mobile field devices via a data service API. GABBs includes a Python map library as well as map widgets that in a few lines of code, generate complete geospatial visualization web interfaces for scientific tools. GABBs also includes powerful tools that can be used with no programming effort. The GeoBuilder tool provides an intuitive wizard for importing multi-variable, geo-located time series data (typical of sensor readings, GPS trackers) to build visualizations supporting data filtering and plotting. MyGeoHub has been used in tutorials at scientific conferences and educational activities for K-12 students. MyGeoHub is also constantly evolving; the recent addition of Jupyter and R Shiny notebook environments enable reproducible, richly interactive geospatial analyses and applications ranging from simple pre-processing to published tools. MyGeoHub is not a monolithic geospatial science gateway, instead it supports diverse needs ranging from just a feature-rich data management system, to complex scientific tools and workflows.

Geomagnetism gave me my bearings

Indian Academy of Sciences (India)

Lawrence

days at the University of Delhi, but also had the opportunity to attend summer ... versity in the United States, I worked on a problem in condensed- matter physics. ... diately after my Ph.D. made me open to the idea of taking up research in an ...

My Life as a Bookbinder: Binding Connection, Knowledge and Authenticity

Directory of Open Access Journals (Sweden)

Tarlen Handayani

2016-08-01

Full Text Available I love to persuade people to write in a journal. In 2008, I received a cultural exchange program scholarship and took the opportunity to learn how to bind books in an Etsy class in Brooklyn, USA. After that, I decided to become a bookbinder. It wasn’t only because of my journaling habit; the decision also fit with my mission to support the literacy movement in Indonesia. This mission is embedded in Tobucil & Klabs, a literacy and hobby community space in Bandung, West Java, that I founded in 2001. The space allows me to spread ideas about literacy through writing and also to share my passion for making hand-bound journals.

Gianco, my Brother

Science.gov (United States)

Rota, Ester Gasperoni

As a child, Gianco (the nickname by which he was known to family and friends) wanted to be a cook. Since cooking has never been my "cup of tea" I gladly allowed him to experiment on a stove that had been given to me for Christmas, a little electric marvel equipped with a real oven. He concocted sauces, baked cookies and cakes, which were eminently edible. Perhaps thanks to his childhood practice, Gianco's cooking was always far better than mine.

Future Wireless Network: MyNET Platform and End-to-End Network Slicing

OpenAIRE

Zhang, Hang

2016-01-01

Future wireless networks are facing new challenges. These new challenges require new solutions and strategies of the network deployment, management, and operation. Many driving factors are decisive in the re-definition and re-design of the future wireless network architecture. In the previously published paper "5G Wireless Network - MyNET and SONAC", MyNET and SONAC, a future network architecture, are described. This paper elaborates MyNET platform with more details. The design principles of ...

Your Face(book) and MySpace: Let's Hook Up

Science.gov (United States)

Gay, P. L.; Foster, T.

2008-06-01

In the public social network venues of MySpace and Facebook, individuals of all ages and nationalities look for like-minded online denizens with whom they can build relationships. Through social networking sites, it is possible for EPO programs to bring together diverse individuals to laugh, learn, and socialize around pet projects and favorite topics. Astronomy is popular among these people, with over 5000 members of the MySpace community listing ``astronomy'' as an interest. By building interesting MySpace and Facebook profiles for your programs, you can plug into the intellectual and social hunger of these individuals. In this workshop, we will discuss the tricks for creating an interesting profile, how to hide such weirdnesses as age and zodiacal sign, and the proper netiquette for nurturing large friends lists and building large communities. Specific emphasis will be given to using Facebook to build one-on-one relationships with program volunteers and students, and how to use MySpace as a way to distribute program announcements to large populations. We will also address the issues of contacting minors, and coping with stalkers and crazies. Come learn how to reach people who already want to learn and love the cosmos, and are just waiting to hear what you have to share.

Self-medication with antibiotics in Sana'a City, Yemen

African Journals Online (AJOL)

*For correspondence: Email: profyahaya@gmail.com; Tel: +60195515611 ... Conclusion: Self-medication with antibiotics is high among consumers in Sana'a City, ... UiTM university, health office in Sana'a City and ... safety of antibiotics. .... laws and policies in Yemen [18]. .... the authors named in this article and all liabilities.

30 CFR 280.27 - When may MMS cancel my permit?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When may MMS cancel my permit? 280.27 Section... Part Interrupted Activities § 280.27 When may MMS cancel my permit? The RD may cancel a permit at any time. (a) If we cancel your permit, the RD will advise you by certified or registered mail 30 days...

30 CFR 285.613 - How will MMS process my SAP?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How will MMS process my SAP? 285.613 Section... Requirements Contents of the Site Assessment Plan § 285.613 How will MMS process my SAP? (a) The MMS will review your submitted SAP, and additional information provided pursuant to § 285.611, to determine if it...

36 CFR 1250.76 - May I email my FOIA appeal?

Science.gov (United States)

2010-07-01

... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false May I email my FOIA appeal... email my FOIA appeal? Yes, you may submit a FOIA appeal via email to http://www.archives.gov/global_pages/inquire_form.html. You must put the words “FOIA Appeal” in the subject line of your email message...

30 CFR 285.628 - How will MMS process my COP?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How will MMS process my COP? 285.628 Section... Requirements Contents of the Construction and Operations Plan § 285.628 How will MMS process my COP? (a) The MMS will review your submitted COP, and the information provided pursuant to § 285.627, to determine...

What Vaccinations Does My Child Need?

Science.gov (United States)

... needed before your child can enter school or childcare. How do vaccines work? Vaccines help your child’s ... routine vaccines is covered by your health insurance company. How do I know when my child should ...

myChEMBL: a virtual machine implementation of open data and cheminformatics tools.

Science.gov (United States)

Ochoa, Rodrigo; Davies, Mark; Papadatos, George; Atkinson, Francis; Overington, John P

2014-01-15

myChEMBL is a completely open platform, which combines public domain bioactivity data with open source database and cheminformatics technologies. myChEMBL consists of a Linux (Ubuntu) Virtual Machine featuring a PostgreSQL schema with the latest version of the ChEMBL database, as well as the latest RDKit cheminformatics libraries. In addition, a self-contained web interface is available, which can be modified and improved according to user specifications. The VM is available at: ftp://ftp.ebi.ac.uk/pub/databases/chembl/VM/myChEMBL/current. The web interface and web services code is available at: https://github.com/rochoa85/myChEMBL.

MyDiabetesMyWay: An Evolving National Data Driven Diabetes Self-Management Platform.

Science.gov (United States)

Wake, Deborah J; He, Jinzhang; Czesak, Anna Maria; Mughal, Fezan; Cunningham, Scott G

2016-09-01

MyDiabetesMyWay (MDMW) is an award-wining national electronic personal health record and self-management platform for diabetes patients in Scotland. This platform links multiple national institutional and patient-recorded data sources to provide a unique resource for patient care and self-management. This review considers the current evidence for online interventions in diabetes and discusses these in the context of current and ongoing developments for MDMW. Evaluation of MDMW through patient reported outcomes demonstrates a positive impact on self-management. User feedback has highlighted barriers to uptake and has guided platform evolution from an education resource website to an electronic personal health record now encompassing remote monitoring, communication tools and personalized education links. Challenges in delivering digital interventions for long-term conditions include integration of data between institutional and personal recorded sources to perform big data analytics and facilitating technology use in those with disabilities, low digital literacy, low socioeconomic status and in minority groups. The potential for technology supported health improvement is great, but awareness and adoption by health workers and patients remains a significant barrier. © 2016 Diabetes Technology Society.

45 CFR 2522.740 - How will the Corporation use my evaluation?

Science.gov (United States)

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false How will the Corporation use my evaluation? 2522... NATIONAL AND COMMUNITY SERVICE AMERICORPS PARTICIPANTS, PROGRAMS, AND APPLICANTS Evaluation Requirements Evaluating Programs: Requirements and Procedures § 2522.740 How will the Corporation use my evaluation? The...

First evaluation of MyOcean altimetric data in the Arctic Ocean

DEFF Research Database (Denmark)

Cheng, Yongcun; Andersen, Ole Baltazar; Knudsen, Per

2012-01-01

The MyOcean V2 preliminary (V2p) data set of weekly gridded sea level anomaly (SLA) maps from 1993 to 2009 over the Arctic region is evaluated against existing altimetric data sets and tide gauge data. Compared with DUACS V3.0.0 (Data Unification and Altimeter Combination System) data set, MyOcean...... V2p data set improves spatial coverage and quality as well as maximum temporal correlation coefficient between altimetry and tide gauge data. The estimated amplitude of sea level annual signal and linear sea level trend from MyOcean data set are evaluated against altimetry from DUACS and RADS (Radar...... Altimeter Database System), the SODA (Simple Ocean Data Assimilation) ocean reanalysis and tide gauge data sets from PSMSL (Permanent Service for Mean Sea Level). The results show that the MyOcean data set fits in-situ measurements better than DUACS data set with respect to amplitude of annual signal...

30 CFR 285.607 - How do I submit my SAP?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I submit my SAP? 285.607 Section 285.607... Assessment Plan and Information Requirements for Commercial Leases § 285.607 How do I submit my SAP? You must submit one paper copy and one electronic version of your SAP to MMS at the address listed in § 285.110(a). ...

MyChemise: A 2D drawing program that uses morphing for visualisation purposes

Science.gov (United States)

2011-01-01

MyChemise (My Chemical Structure Editor) is a new 2D structure editor. It is designed as a Java applet that enables the direct creation of structures in the Internet using a web browser. MyChemise saves files in a digital format (.cse) and the import and export of .mol files using the appropriate connection tables is also possible. MyChemise is available as a free online version in English and German. The MyChemise GUI is designed to be user friendly and can be used intuitively. There is also an English and German program description available as a PDF file. In addition to the known ways of drawing chemical structure formulas, there are also parts implemented in the program that allow the creation of different types of presentation. The morphing module uses this technology as a component for dynamic visualisation. For example, it enables a clear and simple illustration of molecule vibrations and reaction sequences. PMID:22152022

40 CFR 1045.205 - What must I include in my application?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false What must I include in my application... Engine Families § 1045.205 What must I include in my application? This section specifies the information... system components for controlling exhaust emissions, including all auxiliary emission control devices...

40 CFR 63.9600 - What are my operation and maintenance requirements?

Science.gov (United States)

2010-07-01

... instructions for routine and long-term maintenance. (2) Corrective action procedures for bag leak detection... 40 Protection of Environment 14 2010-07-01 2010-07-01 false What are my operation and maintenance... and Maintenance Requirements § 63.9600 What are my operation and maintenance requirements? (a) As...

40 CFR 63.7300 - What are my operation and maintenance requirements?

Science.gov (United States)

2010-07-01

...-term maintenance. (3) Corrective action for all baghouses applied to pushing emissions. In the event a... 40 Protection of Environment 13 2010-07-01 2010-07-01 false What are my operation and maintenance... Battery Stacks Operation and Maintenance Requirements § 63.7300 What are my operation and maintenance...

eEduHeart I: A Multicenter, Randomized, Controlled Trial Investigating the Effectiveness of a Cardiac Web-Based eLearning Platform - Rationale and Study Design.

Science.gov (United States)

Frederix, Ines; Vandenberk, Thijs; Janssen, Leen; Geurden, Anne; Vandervoort, Pieter; Dendale, Paul

Cardiac telerehabilitation includes, in its most comprehensive format, telemonitoring, telecoaching, social interaction, and eLearning. The specific role of eLearning, however, was seldom assessed. The aim of eEduHeart I is to investigate the medium-term effectiveness of the addition of a cardiac web-based eLearing platform to conventional cardiac care. In this prospective, multicenter randomized, controlled trial, 1,000 patients with coronary artery disease will be randomized 1:1 to an intervention group (receiving 1-month unrestricted access to the cardiac eLearning platform in addition to conventional cardiac care) or to conventional cardiac care alone. The primary endpoint is health-related quality of life, assessed by the HeartQoL questionnaire at the 1- and 3-month follow-ups. Secondary endpoints include pathology-specific knowledge and self-reported eLearning platform user experience. Data on the eLearning platform usage will be gathered through web logging during the study period. eEduHeart I will be one of the first studies to report on the added value of eLearning. If the intervention is proven effective, current cardiac telerehabilitation programs can be augmented by including eLearning, too. The platform can then be used as a model for other chronic diseases in which patient education plays a key role. © 2016 S. Karger AG, Basel.

Identification, functional characterization and expression pattern of myeloid differentiation factor 88 (MyD88) in Sepiella japonica.

Science.gov (United States)

Huo, Liping; Bao, Miaomiao; Lv, Zhenming; Chi, Changfeng; Wang, Tianming; Liu, Huihui

2018-05-01

Myeloid differentiation factor 88 (MyD88) is an adaptor protein involved in the interleukin-1 receptor and Toll-like receptor-induced activation of nuclear factor-κB (NF-κB). In this study a novel isoform of MyD88 in Sepiella japonica (SjMyD88) was cloned and functionally characterized (GenBank accession no. AQY56781.1). The complete cDNA sequence of SjMyD88 was 1912 bp and contained a 1017 bp open reading frame encoding 338 amino acid residues, which was similar to its mollusk orthologues in the length. BLASTp analysis suggested the deduced amino acids sequence of SjMyD88 shared high identity to the known MyD88, for instance, 64% identity with Octopus bimaculoides. Sequence analysis revealed two conserved domains, the N-terminal DD and the C-terminal TIR domain appeared in SjMyD88, which was consistent with MyD88 proteins from other species. The fusion expression of SjMyD88 and green fluorescent protein (EGFP) in HEK293 cells was conducted and cytoplasm localization was detected. Meanwhile, the TIR-pmCherry fusion protein showed red fluorescence and mainly distributed in the cytoplasm. After cotransfection MyD88-EGFP and TIR-pmCherry red obviously overlapped and changed to yellowish green. The results suggested that there was the interaction between homologous TIR-pmcherry and MyD88-EGFP. Tissues expression profiles analysis showed that SjMyD88 ubiquitously expressed in all tested tissues with the highest expression in the gills and livers except reproductive related tissue, and it was significantly induced in livers under LPS stress. These data provide insight into the roles of SjMyD88 in the TLR signaling pathway of S. japonica in response to pathogenic bacteria. Copyright © 2018. Published by Elsevier Ltd.

Prophecy and Doubt in Just Above My Head

Directory of Open Access Journals (Sweden)

Christopher Z. Hobson

2015-09-01

Full Text Available Written in the aftermath of the civil rights era’s expansive hopes, James Baldwin’s last novel, Just Above My Head (1979, examines a fundamental issue, the choice between hope and skepticism, or prophecy and doubt. Baldwin approaches this issue by questioning two cornerstone ideas of his fiction, the need for prophetic art and this art’s focus on anticipating a renovated society, often pictured in terms adapted from apocalyptic biblical texts and Gospel music lyrics. Just Above My Head is Baldwin’s fullest presentation of this kind of art and its linkage to apocalyptic hopes. He dramatizes these ideas in the art of his Gospel singer protagonist, particularly in a climactic scene of artistic dedication whose Gospel lyric envisions “tearing down the kingdom of this world.” Yet Baldwin also unsparingly questions these same ideas through plot and the blues-inflected skeptical-tragic consciousness of his narrator. Responding to a 1970s moment when hopes for transcendent justice seemed passé, Just Above My Head’s unique contribution is not to try to resolve the ideas it counterposes, but to face both the possible falseness of prophetic hope and our continuing need for it, and to present the necessity for choice in a final dream that holds the key to the novel’s meaning. In presenting this issue through a sustained double-voiced narrative that reexamines its author’s artistic practice and raises fundamental choices in outlook and conduct, Just Above My Head evidences the continuing artistic vitality of Baldwin’s late fiction.

40 CFR 1054.205 - What must I include in my application?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false What must I include in my application... Certifying Emission Families § 1054.205 What must I include in my application? This section specifies the... controlling exhaust emissions, including all auxiliary emission control devices (AECDs) and all fuel-system...

45 CFR 2522.720 - How many years must my evaluation cover?

Science.gov (United States)

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false How many years must my evaluation cover? 2522.720 Section 2522.720 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR... Evaluating Programs: Requirements and Procedures § 2522.720 How many years must my evaluation cover? (a) If...

40 CFR 63.1447 - What are my operation and maintenance requirements?

Science.gov (United States)

2010-07-01

... corrective action according to written procedures specified in your operation and maintenance plan to... 40 Protection of Environment 12 2010-07-01 2010-07-01 true What are my operation and maintenance... Maintenance Requirements § 63.1447 What are my operation and maintenance requirements? (a) As required by § 63...

32 CFR 37.120 - Can my organization award or administer TIAs?

Science.gov (United States)

2010-07-01

... 32 National Defense 1 2010-07-01 2010-07-01 false Can my organization award or administer TIAs? 37.120 Section 37.120 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS General § 37.120 Can my organization award...

30 CFR 250.111 - Who oversees operations under my welding plan?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Who oversees operations under my welding plan... § 250.111 Who oversees operations under my welding plan? A welding supervisor or a designated person in charge must be thoroughly familiar with your welding plan. This person must ensure that each welder is...

30 CFR 285.606 - What must I demonstrate in my SAP?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I demonstrate in my SAP? 285.606 Section 285.606 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE... demonstrate in my SAP? (a) Your SAP must demonstrate that you have planned and are prepared to conduct the...

36 CFR 1202.76 - Can NARA deny my request for amendment?

Science.gov (United States)

2010-07-01

... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Can NARA deny my request for amendment? 1202.76 Section 1202.76 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS... Can NARA deny my request for amendment? If the system manager denies your request to amend or...

12 CFR 563.146 - Will the OTS permit my capital distribution?

Science.gov (United States)

2010-01-01

... under 12 U.S.C. 1831o(d)(1)(B). (b) Your proposed capital distribution raises safety or soundness... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Will the OTS permit my capital distribution... SAVINGS ASSOCIATIONS-OPERATIONS Capital Distributions § 563.146 Will the OTS permit my capital...

Custom Orthotics Changed My Life

Science.gov (United States)

Holeton, Richard

2010-01-01

The narrator relates his life's downward spiral and miraculous rebound from severe foot problems using animated bullet points, images, charts, and graphs. "Custom Orthotics Changed My Life" is a work of presentation fiction, or slideshow fiction, in the form of a video with an original soundtrack. The music was composed by David Kettler, a…

My Most Memorable AAS Meeting, or How Stephen Hawking's Chauffeur and Chubby Wise's Fiddle Are Related to the Hubble Deep Field (At Least In My Mind and Experience!)

Science.gov (United States)

Lucas, R. A.

1999-05-01

Sometimes, in the most extraordinary conditions and times, strange things happen which remind us of just how small a world we really inhabit, and how so many varied things may suddenly be juxtaposed in our lives, and in the lives of others. My most memorable AAS meeting involves not only the meeting but events while getting there. It was January 1996, and we had just finished our observations and initial data reduction of the Hubble Deep Field, the members of the HDF working group doggedly coming in to the STScI by various means over the December holidays and the New Year, in the midst of several blizzards which even closed STScI for a number of days. Not surprisingly, work on the HDF AAS presentations was ongoing until the last minute, until people left snowy Baltimore for sunny San Antonio. My street was plowed for the first time in a week a few hours before my 6AM flight, so after digging out my car, with no time for sleep, between 3AM and 6AM on the morning I left, I soon discovered my own surprising connections between Stephen Hawking's chauffeur, Chubby Wise's fiddle, and the Hubble Deep Field. I'll elaborate in this paper if you're curious!

TRAM is involved in IL-18 signaling and functions as a sorting adaptor for MyD88.

Directory of Open Access Journals (Sweden)

Hidenori Ohnishi

Full Text Available MyD88, a Toll/interleukin-1 receptor homology (TIR domain-containing adaptor protein, mediates signals from the Toll-like receptors (TLR or IL-1/IL-18 receptors to downstream kinases. In MyD88-dependent TLR4 signaling, the function of MyD88 is enhanced by another TIR domain-containing adaptor, Mal/TIRAP, which brings MyD88 to the plasma membrane and promotes its interaction with the cytosolic region of TLR4. Hence, Mal is recognized as the "sorting adaptor" for MyD88. In this study, a direct interaction between MyD88-TIR and another membrane-sorting adaptor, TRAM/TICAM-2, was demonstrated in vitro. Cell-based assays including RNA interference experiments and TRAM deficient mice revealed that the interplay between MyD88 and TRAM in cells is important in mediating IL-18 signal transduction. Live cell imaging further demonstrated the co-localized accumulation of MyD88 and TRAM in the membrane regions in HEK293 cells. These findings suggest that TRAM serves as the sorting adaptor for MyD88 in IL-18 signaling, which then facilitates the signal transduction. The binding sites for TRAM are located in the TIR domain of MyD88 and actually overlap with the binding sites for Mal. MyD88, the multifunctional signaling adaptor that works together with most of the TLR members and with the IL-1/IL-18 receptors, can interact with two distinct sorting adaptors, TRAM and Mal, in a conserved manner in a distinct context.

40 CFR 35.4070 - How can my group spend TAG money?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false How can my group spend TAG money? 35.4070 Section 35.4070 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL... my group spend TAG money? (a) Your group must use all or most of your funds to procure a technical...

Self-disclosing my ostomy to the dominant culture: an autoethnography.

Science.gov (United States)

Frohlich, Dennis Owen

2012-01-01

Living with an ostomy is a major change to a person's body and poses difficult questions about how to disclose personal medical information to others. This autoethnography examines my time with an ostomy through the lens of co-cultural theory and sheds light on how people with ostomies communicate with the dominant culture, in this case people without ostomies. I discuss how my communication goals and approaches evolved over time.

Dictionary of international commerce

CERN Document Server

Miller, William J

1985-01-01

International trade is vital to the well-being of the international market. No textbook suited virtually every nation, because no nation is my purpose, so I set about to write one. capable of satisfying its material needs beyond the subsistence level entirely from domestic My first task was to define my terms-tar­ iffs, non-tariff barriers, shipping terminology, resources. As a nation's technology advances and edu­ etc. As this labor progressed over many cational levels improve, heavy industry and months, it became evident there was need for manufacturing are often supplanted by serv­ an encyclopedic reference work which fo­ ice industries, as evidenced by the economies cused upon international trade. My enquiries of Europe, North America, and Japan. The having divulged no similar work in English, I shift to a service economy increases import decided to concentrate efforts upon an reliance, especially in the areas of consumer encyclopedia. products and basic industrial commodities, In selecting entries, i...

A new package: MySAS for small angle scattering data analysis

International Nuclear Information System (INIS)

Huang Chaoqiang; Xia Qingzhong; Yan Guanyun; Sun Guang'ai; Chen Bo

2010-01-01

In this paper, A MySAS package, which is verified on Windows XP, can easily convert two-dimensional data in small angle neutron and X-ray scattering analysis, operate individually and execute one particular operation as numerical data reduction or analysis, and graphical visualization. This MySAS package can implement the input and output routines via scanning certain properties, thus recalling completely sets of repetition input and selecting the input files. On starting from the two-dimensional files, the MySAS package can correct the anisotropic or isotropic data for physical interpretation and select the relevant pixels. Over 50 model functions are fitted by the POWELL code using χ 2 as the figure of merit function. (authors)

REAL-LIFE ACTIVITIES: BOOSTING MY STUDENTS’ AWARENESS OF HONESTY IN CREATING GENRE

Directory of Open Access Journals (Sweden)

Rr. Dewi Wahyu Mustikasari

2017-04-01

Full Text Available My students was strugled to write genre without copypasting sentences or texts from the internet. On the other hand, it was a huge challange for me to teach five big writing classes. Each class consisted of 25-30 students who tended (mostly collecting unoriginal writing works. This paper discusses the real-life activities that can be used to enhance my students’ aweareness of honesty in creating genre. My students must write some genres namely recount, descriptive (optional, spoof (optional, procedure, hortatory (optional and analytical exposition (optional text. I also took some benefits of ICT to equip the learning process. Browsing and experiencing the menu of premierskills.britishcouncil.org were the real-life activities that explore their personal memories to be told as the recount text. Then they defined the feature of one of the menu of the previous website to be informed as the descriptive text. Furthermore, they wrote their personal funny experiences which were related to the Indonesian culture as the spoof text. The procedure text can be produced by exploring the daily activities in the pictures such as how to make a cup of tea/coffee, cook a sunny side-up egg, insert sim card into mobile phone, etc. Next, my students visited the tourism and public places in Salatiga, and they observed the strength and weekness of those places as the production of hortatory or analytical exposition text. The real-life activities were able to foster my students’ awareness of honesty. It was fantastic that my students were able to create the genre honestly.

My Home - analysis of the easy and intelligent way to save energy

Energy Technology Data Exchange (ETDEWEB)

Wilke, Goeran (The Danish Electricity Saving Trust (Denmark))

2009-07-01

The concept of the intelligent home is not new, but translating theory into reality presents many challenges. Launched in Denmark in October 2008, My Home is an interactive web portal offering consumers the opportunity to calculate their household energy consumption, receive advice on possible savings, and control and monitor their indoor environments by managing their energy consumption appropriately. This paper describes the software functionality of My Home and examines the energy saving benefits available to consumers who use this system to control and monitor electricity consumption in their homes. The paper further discusses the necessity of having a common infrastructure and standard for use by all producers and suppliers in order to ensure a mass market for compatible equipment and solutions. The analysis focuses on how My Home allows users to map energy consumption in their homes by using drag-and-drop icons to organise and equip a floorplan with their own electrical appliances. My Home features a calculator which automatically works out the annual electricity consumption and displays appropriate savings advice based on manually inputted readings or remote readings supplied by an electricity provider. Detailed statistical evaluation of metered values is also available. The extent to which the use of My Home has resulted in lower energy consumption in the homes of individual users is currently being determined by ongoing research. This involves examining users' motivations and needs, and testing for usability on the basis of ethnographic field work. The results showed that My Home facilitates easy configuration of home control and monitoring systems, which is normally very difficult to perform.

40 CFR 63.10895 - What are my standards and management practices?

Science.gov (United States)

2010-07-01

... Foundries § 63.10895 What are my standards and management practices? (a) If you own or operate an affected... management practices in §§ 63.10885 and 63.10886, the requirements in paragraphs (b) through (e) of this... 40 Protection of Environment 14 2010-07-01 2010-07-01 false What are my standards and management...

30 CFR 285.222 - What does MMS do with my bid?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What does MMS do with my bid? 285.222 Section... Energy Leases Competitive Lease Award Process § 285.222 What does MMS do with my bid? (a) If sealed... any proposal submitted will be made by a panel composed of members selected by MMS. The details of the...

What If My Child Doesn't Take His or Her Asthma Medication?

Science.gov (United States)

... My Child Doesn't Take His or Her Asthma Medication? KidsHealth / For Parents / What if My Child Doesn't Take His or Her Asthma Medication? ... When to Go to the ER if Your Child Has Asthma Asthma Managing Asthma Asthma Center How Do Asthma ...

Uses and Effects of MySpace among Christian Teens and Young Adult

Directory of Open Access Journals (Sweden)

Michael S. Jeffress

2015-07-01

Full Text Available In 2008, MySpace was one of the world’s top Internet destinations.  Behind only Google and Yahoo in Internet traffic in America, it was the most popular social networking site (SNS with some 300,000 profiles being added daily. Although MySpace would soon be supplanted in the SNS world by the likes of Facebook and Twitter, it still has over 50 million unique users each month and over 300,000 video views monthly.  Research performed during the period of its height in popularity is still valuable not only for historical perspective, but also for what it teaches about the habits of SNS users today. This study of the uses and effects of MySpace among Christian teens and young adults (n = 242, computes four composite variables: a Positive Effects Variable (PEV, a Negative Effects Variable (NEV, an Expressing Faith Variable (EFV, and a Friends and Family Variable (FFV, in order to consider interaction effects among various categories such as, age, gender, church attendance frequency, MySpace use experience and frequency, number of MySpace friends, etc.  The results provide important insights for those who wish to maintain and promote a group identity through SNS platforms.

LOOKING INTO MY BACKYARD: SHIFTS IN PROFESSIONAL IDENTITY

Directory of Open Access Journals (Sweden)

Teuku Zulfikar

2012-07-01

Full Text Available Professional development is a long-life journey and rewarding in an academia. Teachers are required to improve their competences. They do not only enhance their subject matters but also upgrade their pedagogical knowledge. Professional development can be conducted through many ways. It could be done through formal education, informal training or self-reflection. This is reflexivity on an English teacher’s professional journey. It scrutinizes phases of language learning and teaching awareness. The article starts with my first contact with English and then goes on to learning-teaching experience in the later phases. The reflection on these experiences shapes my teaching identity and improves teaching competence.

40 CFR 60.2900 - When must I submit my waste management plan?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... Waste Management Plan § 60.2900 When must I submit my waste management plan? You must submit a waste management plan prior to commencing construction, reconstruction, or modification. ...

40 CFR 51.25 - What geographic area must my state's inventory cover?

Science.gov (United States)

2010-07-01

... Emissions Reporting Requirements Specific Reporting Requirements § 51.25 What geographic area must my state... 40 Protection of Environment 2 2010-07-01 2010-07-01 false What geographic area must my state's inventory cover? 51.25 Section 51.25 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED...

安德玛公司与MapMyFitness公司的合并%Mergers and Acquisitions of Under Armour and MapMyFitness

Institute of Scientific and Technical Information of China (English)

曹娜娜

2016-01-01

在激烈的市场竞争环境中，企业唯有不断发展壮大才可以生存下去，企业取得发展可以通过内部投资，也可以通过并购。近几年，企业并购浪潮愈演愈烈，企业并购已经成为市场经济发展的必然产物。文章选取安德玛并购MapMyFitNess这个案例进行研究，第一部分介绍了安德玛公司和MapMyFitNess的基本情况，以及实现合并的相关信息；第二部分分析了安德玛并购MapMyFitNess的原因，主要从进入壁垒和合并协同效应两个方面进行了分析；第三部分阐述了此次合并给安德玛公司在财务方面产生的影响；第四部分结合安德玛目前的发展证实了此次并购是安德玛公司的明智之举。%In the fierce market competition environment, enterprises need constant development to survive. The internal investment and mergers and acquisitions can make enterprises to develop. In recent years, the merger and acquisition of enterprises are fiercer and fiercer, and mergers and acquisitions have become the inevitable product of the development of the market economy. This paper researches the case of mergers and acquisitions of MapMyFitNess by Under Armour. In this paper, the first part introduces the basic situations of Under Armour and MapMyFitNess and the relevant information of the mergers and acquisitions. The second part analyzes the reasons of the merger and acquisition of MapMyFitNess, mainly from two aspects: entry barriers and merger synergies effect. The third part expounds the influence of the mergers and acquisitions on Under Armour in the financial aspect. The fourth part combines with the current development of Andemar to confirm that this acquisition is wise.

Comparing functionality and performance of MySQL and MariaDB database management systems

OpenAIRE

CETINSKI, TEJA

2015-01-01

MySQL je najbolj priljubljen odprtokodni sistem za upravljanje z relacijskimi bazami. Z Oraclovim prevzemom podjetja Sun in s tem MySQL so se pojavili dvomi o nadaljnjem razvoju sistema in ohranjanju njegove odprtokodnosti, kar je povzročilo pojav izpeljank sistema MySQL, ki slednjega neposredno nadomeščajo ter so vedno bolj priljubljene. V okviru diplomske naloge smo zato raziskali združljivost, funkcionalnosti in performančne izboljšave najpopularnejše od njih, MariaDB. V prvem delu naloge ...

30 CFR 285.610 - What must I include in my SAP?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I include in my SAP? 285.610 Section... Requirements Contents of the Site Assessment Plan § 285.610 What must I include in my SAP? Your SAP must... SAP, you must provide the following information: ER29AP09.115 (b) You must provide the results of...

30 CFR 285.224 - What happens if MMS accepts my bid?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What happens if MMS accepts my bid? 285.224... Renewable Energy Leases Competitive Lease Award Process § 285.224 What happens if MMS accepts my bid? If we... withdraw an OCS area in which we have held a lease sale before you and MMS execute the lease in that area...

How Do I Deal with Depression and Adjustment to My Spinal Cord Injury?

Medline Plus

Full Text Available ... with depression and adjustment to my SCI? How do I deal with depression and adjustment to my ... can I apply for Social Security benefits? How do I find a rehabilitation facility? How can I ...

HippDB: a database of readily targeted helical protein-protein interactions.

Science.gov (United States)

Bergey, Christina M; Watkins, Andrew M; Arora, Paramjit S

2013-11-01

HippDB catalogs every protein-protein interaction whose structure is available in the Protein Data Bank and which exhibits one or more helices at the interface. The Web site accepts queries on variables such as helix length and sequence, and it provides computational alanine scanning and change in solvent-accessible surface area values for every interfacial residue. HippDB is intended to serve as a starting point for structure-based small molecule and peptidomimetic drug development. HippDB is freely available on the web at http://www.nyu.edu/projects/arora/hippdb. The Web site is implemented in PHP, MySQL and Apache. Source code freely available for download at http://code.google.com/p/helidb, implemented in Perl and supported on Linux. arora@nyu.edu.

PREFACE: 5th International Conference on Mechatronics (ICOM'13)

Science.gov (United States)

Akramin Shafie, Amir; Raisuddin Khan, Md

2013-12-01

The Fifth International Conference on Mechatronics (ICOM2013), took place in Kuala Lumpur Malaysia from 2-4 July 2013. The biannual conference which started in 2001 is regularly organized by Faculty of Engineering, International Islamic University Malaysia (IIUM) with the aims to serve as a platform for exchange of ideas on advances of in mechatronics and their applications as well as to foster research and worldwide collaboration. The theme for the 2013 conference was 'Mechatronics: Sustainable Development through Innovative Solutions'. The ICOM 2013 Conference consisted of Keynote Speeches (5) and oral contributions (150). The topics of the conference were: Mechatronic systems and Applications Intelligent Systems Control and Instrumentation Signal and Image Processing Machine Vision Robotics and Automation Manufacturing Mechatronics Green Mechatronics Mechatronic Education Smart Materials and Structures Active Vibration Control Computer and Information Technology MEMS and NEMS Biomechatronics and Rehabilitation Engineering Autonomous Systems Energy and Sustainability Transportation System It is our great pleasure to present this volume of IOP Conference Series: Materials Science and Engineering (MSE) to the scientific community to promote further research in these areas. We believe that this volume will be both an excellent source of scientific material in the fast evolving fields that were covered by ICOM 2013. We thank the authors for their enthusiastic and high-grade contributions. We would also like to express our gratitude to the Organizing Committee, the Institutions and Sponsors and everyone who contributed to this conference through their supports and invaluable efforts. Editors Amir A Shafie aashafie@iium.edu.my Raisuddin Khan raisuddin@iium.edu.my Mahbubur Rashid mahbub@iium.edu.my Department of Mechatronics, International Islamic University Malaysia (IIUM), Kuala Lumpur Malaysia Organizing Committee Md Raisuddin Khan Md Mozasser Rahman Shahrul Naim

Verbo fálico: sobre o erotismo divino na canção Sobre todas as coisas de Chico Buarque e Edu Lobo

OpenAIRE

Soares, Márcio Ronei Cravo

2014-01-01

Este artigo pretende realizar uma leitura interpretativa da canção Sobre todas as coisas, composta por Chico Buarque e Edu Lobo, gravada originalmente no LP O grande circo místico (1983). A partir da ideia de canção como espaço que conjuga os textos verbal (a letra) e musical (melodia, harmonia e ritmo), vistos em relação de mútua correspondência, interessa-nos tentar perceber de que modo aspectos daqueles dois textos estão correspondidos e contribuem para a construção discursiva do sentiment...

40 CFR 62.14715 - When must I submit my waste management plan?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 8 2010-07-01 2010-07-01 false When must I submit my waste management... submit my waste management plan? You must submit the waste management plan no later than April 5, 2004. ... POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That...

40 CFR 63.10886 - What are my management practices for binder formulations?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 14 2010-07-01 2010-07-01 false What are my management practices for... What are my management practices for binder formulations? For each furfuryl alcohol warm box mold or... formulation that does not use methanol as a specific ingredient of the catalyst formulation. This requirement...

How Do I Deal with Depression and Adjustment to My Spinal Cord Injury?

Medline Plus

Full Text Available ... to my SCI? How do I deal with depression and adjustment to my SCI? ☷ ▾ Page contents The ... the moment you are injured. Understanding adjustment and depression Adjustment to paralysis is a process of changing ...

My Journey from Python to R

OpenAIRE

Lorgat, Mohamed Wasim

2018-01-01

A lightning talk of my personal experiences in programming, from childhood with languages including Game Maker and DarkBASIC, to now with Python and R. I highlight the underlying principle which, I argue, separates the R community from others.See the reference for further reading material along this line.

40 CFR 60.1125 - What must I include in my siting analysis?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What must I include in my siting... § 60.1125 What must I include in my siting analysis? (a) Include an analysis of how your municipal...) Vegetation. (b) Include an analysis of alternatives for controlling air pollution that minimize potential...

40 CFR 60.1410 - What must I include in my annual report?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What must I include in my annual report... Modification or Reconstruction is Commenced After June 6, 2001 Reporting § 60.1410 What must I include in my...) For municipal waste combustion units that use activated carbon for controlling dioxins/furans or...

40 CFR 60.2060 - When must I submit my waste management plan?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... Management Plan § 60.2060 When must I submit my waste management plan? You must submit a waste management... Commercial and Industrial Solid Waste Incineration Units for Which Construction Is Commenced After November...

12 CFR 516.80 - What language must I use in my publication?

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false What language must I use in my publication? 516.80 Section 516.80 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY APPLICATION PROCESSING PROCEDURES Publication Requirements § 516.80 What language must I use in my publication...

MyOcean Central Information System - Achievements and Perspectives

Science.gov (United States)

Claverie, Vincent; Loubrieu, Thomas; Jolibois, Tony; de Dianous, Rémi; Blower, Jon; Romero, Laia; Griffiths, Guy

2013-04-01

Since 2009, MyOcean (http://www.myocean.eu) is providing an operational service, for forecasts, analysis and expertise on ocean currents, temperature, salinity, sea level, primary ecosystems and ice coverage. The production of observation and forecasting data is done by 42 Production Units (PU). Product download and visualisation are hosted by 25 Dissemination Units (DU). All these products and associated services are gathered in a single catalogue hiding the intricate distributed organization of PUs and DUs. Besides applying INSPIRE directive and OGC recommendations, MyOcean overcomes technical choices and challenges. This presentation focuses on 3 specific issues met by MyOcean and relevant for many Spatial Data Infrastructures: user's transaction accounting, large volume download and stream line the catalogue maintenance. Transaction Accounting: Set up powerful means to get detailed knowledge of system usage in order to subsequently improve the products (ocean observations, analysis and forecast dataset) and services (view, download) offer. This subject drives the following ones: Central authentication management for the distributed web services implementations: add-on to THREDDS Data Server for WMS and NETCDF sub-setting service, specific FTP. Share user management with co-funding projects. In addition to MyOcean, alternate projects also need consolidated information about the use of the cofunded products. Provide a central facility for the user management. This central facility provides users' rights to geographically distributed services and gathers transaction accounting history from these distributed services. Propose a user-friendly web interface to download large volume of data (several GigaBytes) as robust as basic FTP but intuitive and file/directory independent. This should rely on a web service drafting the INSPIRE to-be specification and OGC recommendations for download taking into account that FTP server is not enough friendly (need to know

Of a Village Bomoh and the Lottery: Content Schemata Influence on Second Language Reading

Science.gov (United States)

Radzi, Amizura Hanadi Mohd.; Aziz, Noor Hashima Abd.

2013-01-01

This paper discusses a study on the aspects of content schemata in second language reading, focusing on two contemporary short stories, i.e. "A Quid of Sirih, A Bowl of Water" and "The Lottery." The study explores the cognitive processes of one UiTM Perlis degree level student, reflecting on his L2 reading processes. The…

40 CFR 60.1885 - What must I include in my annual report?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What must I include in my annual report...-Reporting § 60.1885 What must I include in my annual report? Summarize data collected for all pollutants and... controlling dioxins/furans or mercury emissions, include four records: (1) The average carbon feed rates...

40 CFR 60.3011 - When must I submit my waste management plan?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... Model Rule-Waste Management Plan § 60.3011 When must I submit my waste management plan? You must submit a waste management plan no later than 60 days following the initial performance test as specified in...

40 CFR 62.14585 - When must I submit my waste management plan?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 8 2010-07-01 2010-07-01 false When must I submit my waste management... Commenced Construction On or Before November 30, 1999 Waste Management Plan § 62.14585 When must I submit my waste management plan? You must submit a waste management plan no later than April 5, 2004. ...

Myeloid differentiation factor 88 (MyD88-deficiency increases risk of diabetes in mice.

Directory of Open Access Journals (Sweden)

Toru Hosoi

Full Text Available BACKGROUND: Multiple lines of evidence suggest innate immune response pathways to be involved in the development of obesity-associated diabetes although the molecular mechanism underling the disease is unknown. Recent observations suggest that saturated fatty acids can act as a ligand for toll-like receptor (TLR 4, which is thought to mediate obesity-associated insulin resistance. Myeloid differentiation factor 88 (MyD88 is an adapter protein for TLR/IL-1 receptor signaling, which is involved in the activation of inflammatory pathways. To evaluate molecular mechanisms linking obesity-associated diabetes down-stream of TLR4, we investigated physiological role of MyD88 in high-fat diet (HFD-induced obesity. METHODOLOGY/PRINCIPAL FINDINGS: In the present study, we found MyD88-deficient mice fed a HFD had increased circulating levels of insulin, leptin and cholesterol, as well as liver dysfunction (increased induction of ALT levels, increased activation of JNK and cleavage of PARP, which were linked to the onset of severe diabetes. On the other hand, TNF-alpha would not be involved in HFD-induced diabetes in MyD88-deficient mice, because TNF-alpha level was attenuated in MyD88-deficient mice fed with HFD. CONCLUSIONS/SIGNIFICANCE: The present finding of an unexpected role for MyD88 in preventing diabetes may provide a potential novel target/strategy for treating metabolic syndrome.

MyT1 Counteracts the Neural Progenitor Program to Promote Vertebrate Neurogenesis

Directory of Open Access Journals (Sweden)

Francisca F. Vasconcelos

2016-10-01

Full Text Available The generation of neurons from neural stem cells requires large-scale changes in gene expression that are controlled to a large extent by proneural transcription factors, such as Ascl1. While recent studies have characterized the differentiation genes activated by proneural factors, less is known on the mechanisms that suppress progenitor cell identity. Here, we show that Ascl1 induces the transcription factor MyT1 while promoting neuronal differentiation. We combined functional studies of MyT1 during neurogenesis with the characterization of its transcriptional program. MyT1 binding is associated with repression of gene transcription in neural progenitor cells. It promotes neuronal differentiation by counteracting the inhibitory activity of Notch signaling at multiple levels, targeting the Notch1 receptor and many of its downstream targets. These include regulators of the neural progenitor program, such as Hes1, Sox2, Id3, and Olig1. Thus, Ascl1 suppresses Notch signaling cell-autonomously via MyT1, coupling neuronal differentiation with repression of the progenitor fate.

MyD88 expression in the rat dental follicle: Implications for osteoclastogenesis and tooth eruption

Science.gov (United States)

Liu, Dawen; Yao, Shaomian; Wise, Gary E.

2010-01-01

Myeloid differentiation factor 88 (MyD88) is a key adaptor molecule in the interleukin-1 (IL-1) and IL-18 Toll-like receptor signaling pathway. Because it is present in dental follicle (DF) cells in vitro, the purpose of this study was to determine its chronological expression in vivo, as well as its possible role in osteoclastogenesis and tooth eruption. An oligo DNA microarray was used to determine gene expression of MyD88 in vivo in the DFs from the first mandibular molars of postnatal rats from days 1–11. The results showed that MyD88 was expressed maximally at day 3. Using siRNA to knock down MyD88 expression in the DF cells also reduced the gene expression of nuclear factor-kappa B-1 (NFKB1) and monocyte chemoattractant protein 1 (MCP-1). IL-1α up-regulated the expression of NFKB1, MCP-1 and receptor activator of nuclear factor kappa B ligand (RANKL), but knockdown of MyD88 nullified this IL-1α effect. Conditioned medium from DF cells with MyD88 knocked down reduced chemotactic activity for mononuclear cells and reduced osteoclastogenesis as opposed to controls. In conclusion, the maximal expression of MyD88 at day 3 in the DF may contribute to the major burst of osteoclastogenesis needed for eruption by up-regulating MCP-1 and RANKL expression. PMID:20662905

MyCrystals - a simple visual data management program for laboratory-scale crystallization experiments

DEFF Research Database (Denmark)

Løvgreen, Monika Nøhr; Løvgreen, Mikkel; Christensen, Hans Erik Mølager

2009-01-01

MyCrystals is designed as a user-friendly program to display crystal images and list crystallization conditions. The crystallization conditions entry fields can be customized to suit the experiments. MyCrystals is also able to sort the images by the entered crystallization conditions, which...

40 CFR 60.2625 - When must I submit my waste management plan?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... or Before November 30, 1999 Model Rule-Waste Management Plan § 60.2625 When must I submit my waste management plan? You must submit a waste management plan no later than the date specified in table 1 of this...

5 CFR 894.602 - May I cancel my enrollment at any time?

Science.gov (United States)

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false May I cancel my enrollment at any time... Cancellation of Coverage § 894.602 May I cancel my enrollment at any time? No. You may only cancel your enrollment during an open season. Exceptions: You may cancel your dental and/or vision enrollment if you...

30 CFR 285.437 - When can my lease or grant be canceled?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When can my lease or grant be canceled? 285.437... Administration Lease Or Grant Cancellation § 285.437 When can my lease or grant be canceled? (a) The Secretary will cancel any lease or grant issued under this part upon proof that it was obtained by fraud or...

30 CFR 250.110 - What must I include in my welding plan?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I include in my welding plan? 250.110... must I include in my welding plan? You must include all of the following in the Welding Plan that you... qualified personnel weld; (c) Practices and procedures for safe welding that address: (1) Welding in...

40 CFR 62.14432 - When must my waste management plan be completed?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 8 2010-07-01 2010-07-01 false When must my waste management plan be... Before June 20, 1996 Waste Management Plan § 62.14432 When must my waste management plan be completed? As specified in §§ 62.14463 and 62.14464, you must submit your waste management plan with your initial report...

From my Home: Dvarionas: Elegie / Rob Cowan

Index Scriptorium Estoniae

Cowan, Rob

1997-01-01

Uuest heliplaadist "From my Home: Dvarionas: Elegie; Pärt: Fratres; Barkauskas: Partita; Vasks: Musica Dolorosa; Pelecis: Concerto for Violin, Piano and String Orchestra, "Neverthless"; Plakidis: Two Grasshopper Dances; Tüür: Conversio. Deutsche Kammerphilharmonie. Teldec 0630-14654-2 (79 minutes:DDD)

Molecular identification and functional analysis of two variants of myeloid differentiation factor 88 (MyD88) from disk abalone (Haliotis discus discus).

Science.gov (United States)

Priyathilaka, Thanthrige Thiunuwan; Bathige, S D N K; Lee, Seongdo; Lee, Jehee

2018-02-01

Myeloid differentiation factor 88 (MyD88) is a crucial adaptor protein of the Toll-like receptor (TLR)- and interleukin 1 receptor-mediated signaling pathways and is involved in a diverse array of inflammatory responses via NF-κB activation. In the present study, two MyD88 variants were identified from disk abalone (Haliotis discus discus) and designated AbMyD88-2 and AbMyD88-X. The deduced AbMyD88-2 and AbMyD88-X comprised 433 and 354 amino acids with predicted molecular masses of 48.85 kDa and 40.17 kDa, respectively. AbMyD88-2 and AbMyD88-X possessed typical MyD88 domain structural features including an N-terminal death domain (DD) and C-terminal toll interleukin 1 receptor (TIR) domain similar to those in mammals. Expression analysis of AbMyD88-2 and AbMyD88-X mRNA at different early embryonic developmental stages of abalone by qPCR revealed that their constitutive expression at all developmental stages analyzed with the considerably higher values at the 16-cell (AbMyD88-2) and morula stages (AbMyD88-X). In unchallenged disk abalones, AbMyD88-2 was highly expressed in muscles, while AbMyD88-X mRNA was predominantly transcribed in hemocytes. Moreover, AbMyD88-2 and AbMyD88-X mRNA were differentially modulated in abalone hemocytes after a challenge with live bacteria (Vibrio parahaemolyticus, Listeria monocytogenes), virus (viral hemorrhagic septicemia virus), and pathogen-associated molecular patterns (lipopolysaccharides and Poly I:C). Overexpression of AbMyD88-2 and AbMyD88-X in HEK293T cells induced the activation of the NF-κB promoter. AbMyD88-2 and AbMyD88-X involvement in inflammatory responses was characterized by their overexpression in RAW264.7 murine macrophage cells. These results revealed comparatively higher NO (Nitric oxide) production, induction of inflammatory mediator genes (iNOS and COX2), and proinflammatory genes (IL1β, IL6 and TNFα) expression in abalone MyD88s-overexpressing cells than in mock control in the presence or absence of LPS

The E-health Literacy Demands of Australia's My Health Record: A Heuristic Evaluation of Usability.

Science.gov (United States)

Walsh, Louisa; Hemsley, Bronwyn; Allan, Meredith; Adams, Natalie; Balandin, Susan; Georgiou, Andrew; Higgins, Isabel; McCarthy, Shaun; Hill, Sophie

2017-01-01

My Health Record is Australia's electronic personal health record system, which was introduced in July 2012. As of August 2017, approximately 21 percent of Australia's total population was registered to use My Health Record. Internationally, usability issues have been shown to negatively influence the uptake and use of electronic health record systems, and this scenario may particularly affect people who have low e-health literacy. It is likely that usability issues are negatively affecting the uptake and use of My Health Record in Australia. To identify potential e-health literacy-related usability issues within My Health Record through a heuristic evaluation method. Between September 14 and October 12, 2016, three of the authors conducted a heuristic evaluation of the two consumer-facing components of My Health Record-the information website and the electronic health record itself. These two components were evaluated against two sets of heuristics-the Health Literacy Online checklist and the Monkman Heuristics. The Health Literacy Online checklist and Monkman Heuristics are evidence-based checklists of web design elements with a focus on design for audiences with low health literacy. During this heuristic evaluation, the investigators individually navigated through the consumer-facing components of My Health Record, recording instances where the My Health Record did not conform to the checklist criteria. After the individual evaluations were completed, the investigators conferred and aggregated their results. From this process, a list of usability violations was constructed. When evaluated against the Health Literacy Online Checklist, the information website demonstrated violations in 12 of 35 criteria, and the electronic health record demonstrated violations in 16 of 35 criteria. When evaluated against the Monkman Heuristics, the information website demonstrated violations in 7 of 11 criteria, and the electronic health record demonstrated violations in 9 of 11

Downregulation of adaptor protein MyD88 compromises the angiogenic potential of B16 murine melanoma

Science.gov (United States)

Araya, Paula; Nuñez, Nicolás Gonzalo; Mena, Hebe Agustina; Bocco, José Luis; Negrotto, Soledad; Maccioni, Mariana

2017-01-01

The mechanisms that link inflammatory responses to cancer development remain a subject of intense investigation, emphasizing the need to better understand the cellular and molecular pathways that create a tumor promoting microenvironment. The myeloid differentiation primary response protein MyD88 acts as a main adaptor molecule for the signaling cascades initiated from Toll-like receptors (TLRs) and the interleukin 1 receptor (IL-1R). MyD88 has been shown to contribute to tumorigenesis in many inflammation-associated cancer models. In this study, we sought to better define the role of MyD88 in neoplastic cells using a murine melanoma model. Herein, we have demonstrated that MyD88 expression is required to maintain the angiogenic switch that supports B16 melanoma growth. By knocking down MyD88 we reduced TLR-mediated NF-κB activation with no evident effects over cell proliferation and survival. In addition, MyD88 downregulation was associated with a decrease of HIF1α levels and its target gene VEGF, in correlation with an impaired capability to induce capillary sprouting and tube formation of endothelial cells. Melanomas developed from cells lacking MyD88 showed an enhanced secretion of chemoattractant ligands such as CCL2, CXCL10 and CXCL1 and have an improved infiltration of macrophages to the tumor site. Our results imply that cell-autonomous signaling through MyD88 is required to sustain tumor growth and underscore its function as an important positive modulator of tumor angiogenesis. PMID:28662055

40 CFR 63.6125 - What are my monitor installation, operation, and maintenance requirements?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 12 2010-07-01 2010-07-01 true What are my monitor installation... Combustion Turbines Testing and Initial Compliance Requirements § 63.6125 What are my monitor installation... limitation and you are not using an oxidation catalyst, you must continuously monitor any parameters...

Signaling through MyD88 regulates leukocyte recruitment after brain injury

DEFF Research Database (Denmark)

Babcock, Alicia A; Toft-Hansen, Henrik; Owens, Trevor

2008-01-01

hippocampus. We now show that significant leukocyte entry into the EC occurs within 3-12 h of stab injury. Whereas T cells showed small, gradual increases over 8 days, macrophage infiltration was pronounced and peaked within 12-24 h. MyD88 deficiency significantly reduced macrophage and T cell recruitment...... for TNF-alpha, IL-1beta, and CCL2, which increased >50-fold after stab injury in C57BL/6 mice at the time of peak expression, were severely reduced in injured MyD88 knockout mice. Leukocyte recruitment and gene expression were unaffected in TLR2-deficient or TLR4 mutant mice. No significant differences...... in gene expression were observed in mice lacking IL-1R or IL-18R. These data show that MyD88-dependent signaling mediates proinflammatory gene expression and leukocyte recruitment after CNS injury....

MyD88 But Not TRIF Is Essential for Osteoclastogenesis Induced by Lipopolysaccharide, Diacyl Lipopeptide, and IL-1α

Science.gov (United States)

Sato, Nobuaki; Takahashi, Naoyuki; Suda, Koji; Nakamura, Midori; Yamaki, Mariko; Ninomiya, Tadashi; Kobayashi, Yasuhiro; Takada, Haruhiko; Shibata, Kenichiro; Yamamoto, Masahiro; Takeda, Kiyoshi; Akira, Shizuo; Noguchi, Toshihide; Udagawa, Nobuyuki

2004-01-01

Myeloid differentiation factor 88 (MyD88) plays essential roles in the signaling of the Toll/interleukin (IL)-1 receptor family. Toll–IL-1 receptor domain-containing adaptor inducing interferon-β (TRIF)-mediated signals are involved in lipopolysaccharide (LPS)-induced MyD88-independent pathways. Using MyD88-deficient (MyD88−/−) mice and TRIF-deficient (TRIF−/−) mice, we examined roles of MyD88 and TRIF in osteoclast differentiation and function. LPS, diacyl lipopeptide, and IL-1α stimulated osteoclastogenesis in cocultures of osteoblasts and hemopoietic cells obtained from TRIF−/− mice, but not MyD88−/− mice. These factors stimulated receptor activator of nuclear factor-κB ligand mRNA expression in TRIF−/− osteoblasts, but not MyD88−/− osteoblasts. LPS stimulated IL-6 production in TRIF−/− osteoblasts, but not TRIF−/− macrophages. LPS and IL-1α enhanced the survival of TRIF−/− osteoclasts, but not MyD88−/− osteoclasts. Diacyl lipopeptide did not support the survival of osteoclasts because of the lack of Toll-like receptor (TLR)6 in osteoclasts. Macrophages expressed both TRIF and TRIF-related adaptor molecule (TRAM) mRNA, whereas osteoblasts and osteoclasts expressed only TRIF mRNA. Bone histomorphometry showed that MyD88−/− mice exhibited osteopenia with reduced bone resorption and formation. These results suggest that the MyD88-mediated signal is essential for the osteoclastogenesis and function induced by IL-1 and TLR ligands, and that MyD88 is physiologically involved in bone turnover. PMID:15353553

A Study of the Third Space, Hybridity, and Colonial Mimicry in Athol Fugard’s My Children! My Africa!

Directory of Open Access Journals (Sweden)

Ghasemi Parvin

2017-08-01

Full Text Available South Africa, like many other Eastern countries, was a victim of the brutal phenomenon called colonialism. Its people suffered a lot but did not give up protesting against it. Literature was often used as a means to demonstrate the problems and realities of the society. Therefore, the literary texts can be considered an effective weapon in this battle. One of these influential people is Harold Athol Lanigan Fugard who is known for his anti-apartheid plays. This article scrutinizes the relation between the colonizer and the colonized in Athol Fugard’s My Children! My Africa! based on Homi Bhabha’s ideas. According to him, the relation between the whites and the blacks becomes reciprocal in the third space of enunciation. Despite their differences, they try to live peacefully. The mimicry strategy is employed by the colonized to prevent total resemblance. They are dependent on each other notwithstanding their opposition, and both are aware of this, which makes them stick together.

Why Is My Voice Changing? (For Teens)

Science.gov (United States)

... enter puberty earlier or later than others. How Deep Will My Voice Get? How deep a guy's voice gets depends on his genes: ... of Use Notice of Nondiscrimination Visit the Nemours Web site. Note: All information on TeensHealth® is for ...

12 CFR 563b.435 - What happens to my corporate existence after conversion?

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false What happens to my corporate existence after... What happens to my corporate existence after conversion? Your corporate existence will continue following your conversion, unless you convert to a state-chartered stock savings association and state law...

MyWelch: building an information portal system in a medical library environment.

Science.gov (United States)

Zhang, Dongming; Zambrowicz, Caroline; Zhou, Hong; Roderer, Nancy

2003-01-01

MyWelch is a medical library portal system that users can use to create customized web sites that reflect their research needs and personal interests. In the MyWelch environment, faculty and students are empowered to take a greater role in identifying their needs and determining their requirements in the electronic environment. The portal system also facilitates interaction among library users and staff.

12 CFR 563b.330 - How do I price my conversion shares?

Science.gov (United States)

2010-01-01

... FROM MUTUAL TO STOCK FORM Standard Conversions Offers and Sales of Stock § 563b.330 How do I price my conversion shares? (a) You must sell your conversion shares at a uniform price per share and at a total price... 12 Banks and Banking 5 2010-01-01 2010-01-01 false How do I price my conversion shares? 563b.330...

myPhyloDB: a local web server for the storage and analysis of metagenomic data.

Science.gov (United States)

Manter, Daniel K; Korsa, Matthew; Tebbe, Caleb; Delgado, Jorge A

2016-01-01

myPhyloDB v.1.1.2 is a user-friendly personal database with a browser-interface designed to facilitate the storage, processing, analysis, and distribution of microbial community populations (e.g. 16S metagenomics data). MyPhyloDB archives raw sequencing files, and allows for easy selection of project(s)/sample(s) of any combination from all available data in the database. The data processing capabilities of myPhyloDB are also flexible enough to allow the upload and storage of pre-processed data, or use the built-in Mothur pipeline to automate the processing of raw sequencing data. myPhyloDB provides several analytical (e.g. analysis of covariance,t-tests, linear regression, differential abundance (DESeq2), and principal coordinates analysis (PCoA)) and normalization (rarefaction, DESeq2, and proportion) tools for the comparative analysis of taxonomic abundance, species richness and species diversity for projects of various types (e.g. human-associated, human gut microbiome, air, soil, and water) for any taxonomic level(s) desired. Finally, since myPhyloDB is a local web-server, users can quickly distribute data between colleagues and end-users by simply granting others access to their personal myPhyloDB database. myPhyloDB is available athttp://www.ars.usda.gov/services/software/download.htm?softwareid=472 and more information along with tutorials can be found on our websitehttp://www.myphylodb.org. Database URL:http://www.myphylodb.org. Published by Oxford University Press 2016. This work is written by US Government employees and is in the public domain in the United States.

Facebook and MySpace: complement or substitute for face-to-face interaction?

Science.gov (United States)

Kujath, Carlyne L

2011-01-01

Previous studies have claimed that social-networking sites are used as a substitute for face-to-face interaction, resulting in deteriorating relationship quality and decreased intimacy among its users. The present study hypothesized that this type of communication is not a substitute for face-to-face interaction; rather, that it is an extension of communication with face-to-face partners. A survey was administered to examine the use of Facebook and MySpace in this regard among 183 college students. The study confirmed that Facebook and MySpace do act as an extension of face-to-face interaction, but that some users do tend to rely on Facebook and MySpace for interpersonal communication more than face-to-face interaction.

Beginning PHP and MySQL 5 from novice to professional

CERN Document Server

Gilmore, W Jason

2006-01-01

Written for the budding web developer searching for a powerful, low-cost solution for building flexible, dynamic web sites.Essentially three books in one: provides thorough introductions to the PHP language and the MySQL database, and shows you how these two technologies can be effectively integrated to build powerful websites.Provides over 500 code examples, including real-world tasks such as creating an auto-login feature, sending HTML-formatted e-mail, testing password guessability, and uploading files via a web interface.Updated for MySQL 5, includes new chapters introducing triggers, stor

A Biogeochemical Oceanographer at Sea: My Life with Nitrogen and a Nod to Silica

Science.gov (United States)

Dugdale, Richard C.

2018-01-01

My evolution from electrical engineering student to limnologist and then to oceanographer was a consequence of generous mentoring, which led to my use of the 15N tracer technique to measure nitrogen fixation in aquatic systems. The concept of new and regenerated production arose when I applied this method to measure nitrate and ammonium uptake in marine ecosystems. I then showed that enzyme kinetics could be applied to algal nitrogen uptake and used a silicate pump to explain silicate limitation of diatoms in coastal and equatorial upwelling systems. These concepts are now recognized as modern nutrient paradigms in biogeochemical oceanography. My interest in nutrients required field studies and led to my passion for the study of upwelling ecosystems and the establishment of two major international programs, with numerous advisors, collaborators, and students helping along the way.

My Life with State Space Models

DEFF Research Database (Denmark)

Lundbye-Christensen, Søren

2007-01-01

. The conceptual idea behind the state space model is that the evolution over time in the object we are observing and the measurement process itself are modelled separately. My very first serious analysis of a data set was done using a state space model, and since then I seem to have been "haunted" by state space...

30 CFR 280.29 - Will MMS monitor the environmental effects of my activity?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Will MMS monitor the environmental effects of my activity? 280.29 Section 280.29 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... Obligations Under This Part Environmental Issues § 280.29 Will MMS monitor the environmental effects of my...

40 CFR 141.561 - What happens if my system's turbidity monitoring equipment fails?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 22 2010-07-01 2010-07-01 false What happens if my system's turbidity... Disinfection-Systems Serving Fewer Than 10,000 People Individual Filter Turbidity Requirements § 141.561 What happens if my system's turbidity monitoring equipment fails? If there is a failure in the continuous...

ANALISIS KEPUASAN PASIEN TERHADAP KUALITAS PELAYANAN PERAWATAN GIGI DI KLINIK GIGI MY DENTAL CARE SURABAYA

Directory of Open Access Journals (Sweden)

Adityarani Putranti

2016-10-01

Full Text Available Kebutuhan masyarakat yang semakin tinggi akan jasa layanan kesehatan membuat ekspektasi masyarakat terhadap layanan kesehatan yang baik juga semakin tinggi. Pelayanan gigi dan mulut, merupakan salah satu pelayanan kesehatan dasar pada masyarakat. Klinik gigi My Dental Care Surabaya merupakan salah satu klinik gigi yang terletak di Surabaya Selatan. Klinik Gigi My Dental Care memiliki permasalahan belum tercapainya target jumlah kunjungan pasien sebesar 120 pasien per bulan selama tahun 2013-2014. Jenis penelitian ini adalah penelitian analitik observasional dengan pengumpulan data secara cross sectional. Pengambilan sampel dengan metode simple random sampling dan jumlah sampel sebesar 30 orang. Penelitian ini dilakukan pada pasien yang melakukan perawatan gigi di Klinik Gigi My Dental Care Surabaya. Kata Kunci: Kepuasan Pelanggan, Kualitas Pelayanan, Klinik Gigi My Dental Care Surabaya

30 CFR 285.810 - What must I include in my Safety Management System?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I include in my Safety Management System? 285.810 Section 285.810 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR..., COPs and GAPs Safety Management Systems § 285.810 What must I include in my Safety Management System...

40 CFR 1051.1 - Does this part apply for my vehicles or engines?

Science.gov (United States)

2010-07-01

... (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM RECREATIONAL ENGINES AND VEHICLES Overview and Applicability § 1051.1 Does this part apply for my vehicles or engines? (a) The regulations in this part 1051... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Does this part apply for my vehicles...

12 CFR 516.55 - What information must I include in my public notice?

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false What information must I include in my public notice? 516.55 Section 516.55 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY APPLICATION PROCESSING PROCEDURES Publication Requirements § 516.55 What information must I include in my...

21 CFR 822.17 - How long will your review of my submission take?

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false How long will your review of my submission take... SERVICES (CONTINUED) MEDICAL DEVICES POSTMARKET SURVEILLANCE FDA Review and Action § 822.17 How long will your review of my submission take? We will review your submission within 60 days of receipt. ...

Planetary Science Research Discoveries (PSRD) www.psrd.hawaii.edu

Science.gov (United States)

Martel, L.; Taylor, J.

2010-12-01

NASA's Year of the Solar System is celebrating not only Solar System mission milestones but also the collective data reduction and analysis that happens here on Earth. The Cosmochemistry Program of NASA's Science Mission Directorate takes a direct approach to enhance student learning and engage the public in the latest research on meteorites, asteroids, planets, moons, and other materials in our Solar System with the website known as PSRD. The Planetary Science Research Discoveries (PSRD) website at www.psrd.hawaii.edu explores the science questions that researchers are actively pursuing about our Solar System and explains how the answers are discovered and what they mean. The site helps to convey the scientific basis for sample study to the broader scientific community and the excitement of new results in cosmochemistry to the general public. We share with our broad audience the fascinating discoveries made by cosmochemists, increasing public awareness of the value of sample-focused research in particular and of fundamental scientific research and space exploration in general. The scope of the website covers the full range of cosmochemical research and highlights the investigations of extraterrestrial materials that are used to better understand the origin of the Solar System and the processes by which planets, moons, and small bodies evolve. We relate the research to broader planetary science themes and mission results. Articles are categorized into: asteroids, comets, Earth, instruments of cosmochemistry, Jupiter system, Mars, Mars life issues, Mercury, meteorites, Moon, origins, and space weathering. PSRD articles are based on peer-reviewed, journal publications. Some PSRD articles are based on more than one published paper in order to present multiple views and outcomes of research on a topic of interest. To date, 150 PSRD articles have been based on 184 journal articles (and counting) written by some of the most active cosmochemists and planetary scientists

Blood Pressure Medications: Can They Raise My Triglycerides?

Science.gov (United States)

... medications: Can they raise my triglycerides? Can some blood pressure medications cause an increase in triglycerides? Answers from Sheldon G. Sheps, M.D. Yes, some blood pressure medications can affect triglyceride and cholesterol levels. Hydrochlorothiazide ...

Fasting Diet: Can It Improve My Heart Health?

Science.gov (United States)

... health? Is it true that occasionally following a fasting diet can reduce my risk of heart disease? ... t sure why, but it seems that regularly fasting — severely restricting food and drink for a 24- ...

My-Bookstore: Using Information Technology to Support Children's Classroom Reading and Book Recommendation

Science.gov (United States)

Chien, Tzu-Chao; Chen, Zhi-Hong; Ko, Hwa-Wei; Ku, Yu-Min; Chan, Tak-Wai

2015-01-01

This paper describes a learning system, named My-Bookstore, where students buy (make records of) books (paper books) which they have read, and then sell (recommend) the books they like to others. This system is designed to encourage elementary students' classroom reading and book recommendation. The long-term influence of the My-Bookstore system…

Poetic devices as part of the trauma narrative in Country of My Skull ...

African Journals Online (AJOL)

This article investigates the role of poetic devices in a trauma narrative like Country of My Skull. The nature and characteristics of a trauma narrative are described with reference to Country of My Skull and Antjie Krog's style as poet and journalist. The theory and role of figurative language in trauma narratives suggest an ...

30 CFR 253.50 - How can MMS refuse or invalidate my OSFR evidence?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How can MMS refuse or invalidate my OSFR... can MMS refuse or invalidate my OSFR evidence? (a) If MMS determines that any OSFR evidence you submit... acceptable evidence without being subject to civil penalty under § 253.51. (b) MMS may immediately and...

My Family Health Portrait, A tool from the Surgeon General | NIH MedlinePlus the Magazine

Science.gov (United States)

... of this page please turn Javascript on. My Family Health Portrait, A tool from the Surgeon General ... use Why is it important to know my family medical history? Your family medical history is a ...

The Grey Faces of Academic Workers: On the Non-Emancipatory Resistance of Polish Humanists to the Edu-Factory Reform of Academia

Science.gov (United States)

Szwabowski, Oskar

2016-01-01

In this article I deal with the Polish discourse generated by academics facing a reform of higher education. My primary interest is to what extent their statement enables or disables emancipatory practice. I point out that the structure of academics' prevalent discourse in the face of education-factory reform makes liberation impossible.…

Design of Smart Home Systems Prototype Using MyRIO

Science.gov (United States)

Ratna Wati, Dwi Ann; Abadianto, Dika

2017-06-01

This paper presents the design of smart home systems prototype. It applies. MyRIO 1900 embedded device as the main controller of the smart home systems. The systems include wireless monitoring systems and email based notifications as well as data logging. The prototype systems use simulated sensor such as temperature sensor, push button as proximity sensor, and keypad while its simulated actuators are buzzer as alarm system, LED as light and LCD. Based on the test and analysis, the smart home systems prototype as well as the wireless monitoring systems have real time responses when input signals are available. Tbe performance of MyRIO controller is excellent and it results in a stable system.

Application of MySQL in instantaneous profile gauge system

International Nuclear Information System (INIS)

Guo Xiaojing; Miao Jichen; Wu Zhifang

2011-01-01

As equipment in the hot rolling plate plant for online measurement of strip steel, the instantaneous profile gauge is used to measure instant crown of hot rolling strips and feed back the crown to the rolling mill to adjust strip profile. During the measurement, a large amount of data need to be stored reasonably for query, display, computation and other processing, while a database management software can make it happen. Based on such features of MySQL as small size, fast speed, low cost and open source codes, a database function was implemented in the instantaneous profile gauge for data storage, query and maintenance, by applying MySQL database management system and integrating with the control interface. (authors)

What Do We Learn about Technical Communication in Hungary through My Students and My Hungarian Colleagues: An Initial Investigation

Science.gov (United States)

Ding, Daniel D.

2018-01-01

Very few articles exist that document technical communication in Hungary. My Fulbright research reveals two general points: First, technical communication pedagogy stresses correct use of professional terms and phrases in technical translations or technical articles for fictional audiences. Second, it does not emphasize the importance of…

Knowledge maintenance in myCBR

OpenAIRE

Aul, Vani; Sauer, Christian; Roth-Berghofer, Thomas

2014-01-01

CBR systems, being knowledge based systems, process knowledge. Due to changes in the environment a CBR system’s knowledge model can become outdated, thus creating a need for constant maintenance of said knowledge model. In this paper, we describe an implementation of (semi-)automatic knowledge maintenance of two of the four knowledge containers of CBR systems, specifically case base maintenance and maintenance of similarity measures within the CBR system development SDK myCBR. We describe our...

My relational self psychology.

Science.gov (United States)

Teicholz, Judith Guss

2009-04-01

In this article, I suggest recent sources of influence on psychoanalysis and describe a contemporary relational self psychology that is my personal attempt at integration. Even with this integration, I struggle to find the right "therapeutic" balance between my essential but imperfect instrument for empathic listening, on the one hand, and the risks of authentic engagement, on the other. These dialectical tensions in me mirror those in the psychoanalytic community as a whole, poised between a scientifically based practice and a healing "art"--or between a complex but teachable methodology or discipline-and an ordinary (yet extraordinary) human relationship in which spontaneity and even improvisation play a role. Complicating this balancing act, there is new evidence from neuroscientists, attachment theorists, and infant-caregiver researchers that, from birth onward, bidirectional influences on brain and psychic development create contingent and unpredictable outcomes in every intimately related dyad. Thus, the contemporary analyst must expect to be changed by the work and--while taking full responsibility for his or her own contribution--must recognize patient and analyst as co-creators of the psychoanalytic project. At the same time that we now recognize contingency, complexity, and chaos at the heart of human minds and relationships, we also acknowledge the central importance of a sense of continuity and coherence as the individual undertakes the pursuit of goals and relationships in life. What kind of relationship can facilitate these qualities in the sense of self? That is the question that this article undertakes to answer.

21 CFR 822.26 - If my company changes ownership, what must I do?

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false If my company changes ownership, what must I do? 822.26 Section 822.26 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... my company changes ownership, what must I do? You must notify us within 30 days of any change in...

43 CFR 30.243 - How will the judge decide my petition for reopening?

Science.gov (United States)

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false How will the judge decide my petition for... the judge decide my petition for reopening? (a) If the judge finds that proper grounds are not shown, the judge will issue an order denying the petition for reopening and giving the reasons for the denial...

30 CFR 241.76 - Can MMS reduce my penalty once it is assessed?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Can MMS reduce my penalty once it is assessed? 241.76 Section 241.76 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... Provisions § 241.76 Can MMS reduce my penalty once it is assessed? Under 30 U.S.C. 1719(g), the Director or...

40 CFR 63.6105 - What are my general requirements for complying with this subpart?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 12 2010-07-01 2010-07-01 true What are my general requirements for... Turbines General Compliance Requirements § 63.6105 What are my general requirements for complying with this..., oxidation catalyst emission control device or other air pollution control equipment, and monitoring...

30 CFR 250.136 - How will MMS determine if my operating performance is unacceptable?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How will MMS determine if my operating... Disqualification § 250.136 How will MMS determine if my operating performance is unacceptable? In determining if your operating performance is unacceptable, MMS will consider, individually or collectively: (a...

40 CFR 1054.255 - What decisions may EPA make regarding my certificate of conformity?

Science.gov (United States)

2010-07-01

... my certificate of conformity? 1054.255 Section 1054.255 Protection of Environment ENVIRONMENTAL... regarding my certificate of conformity? (a) If we determine your application is complete and shows that the... of conformity for your emission family for that model year. We may make the approval subject to...

40 CFR 1060.255 - What decisions may EPA make regarding my certificate of conformity?

Science.gov (United States)

2010-07-01

... my certificate of conformity? 1060.255 Section 1060.255 Protection of Environment ENVIRONMENTAL... regarding my certificate of conformity? (a) If we determine your application is complete and shows that the... of conformity for your emission family for that production period. We may make the approval subject...

3D Geo-Structures Visualization Education Project (3dgeostructuresvis.ucdavis.edu)

Science.gov (United States)

Billen, M. I.

2014-12-01

experience in regions without good geologic outcrops, or for students with disabilities that prevent them from going into the field. These exercises and modules are available from 3dgeostructuresvis.ucdavis.edu. We plan to add several new structures to the site each year. This project was funded by a National Science Foundation CAREER grant to Billen.

STEeM- STEM&eTwinning in my school

Science.gov (United States)

Nicolaita, Cristina

2017-04-01

My name is Cristina Nicolăiță, I am a teacher of Physics and Computer Science in Gheorghe Magheru School, Caracal, Romania, and a Romanian Scientix&eTwinning ambassador. My poster presents the two eTwinning projects my students are actively involved in, "STEM Club" and "What's the weather like #eTwCitizen2016", with partners mostly from the Mediterranean area. STEM CLUB project focuses on the introductory level STEM activities, as well as awareness of the STEM fields and occupations. This initial step provides standards-based structured inquiry-based and real world problem-based learning, connecting all four of the STEM subjects. Project's basic aims are: 1. increasing student STEM ability, engagement, participation and aspiration 2. increasing teacher capacity and STEM teaching quality 3. supporting STEM education opportunities 4. facilitating effective school partnerships 5. building a strong evidence base 6. improving ICT skills During the second eTwinning project, What's the weather like #eTwCitizen2016", students will investigate weather in our lives, culture and science, in literature (including popular sayings and informative digital literacy), languages, science and Maths( including astronomy, physics, environmental studies) social sciences, religion, art, music, history, psychology (ways of thinking at different weather conditions, feelings related with the weather forecast, careers related to weather, climate change and sustainability).They will use the different intelligences they possess, bringing their contribution to the team work and developing the ability to identify, find, evaluate, and use information effectively.

How Can I Relieve My Pregnancy Leg Cramps?

Science.gov (United States)

... Fitness Diseases & Conditions Infections Drugs & Alcohol School & Jobs Sports Expert Answers (Q&A) Staying Safe Videos for Educators Search English Español How Can I Relieve My Pregnancy Leg Cramps? KidsHealth / For Parents / How Can I ...

How AMS dating changed my life

International Nuclear Information System (INIS)

Spriggs, M.

2001-01-01

Accelerator mass spectrometry (AMS) radiocarbon dating was developed in the late 1970s. Remembering back to a time before AMS dating was available to archaeologists is a bit like trying to remember how we ever survived without desktop computers, email or automatic teller machines. My own particular interest in AMS dating was an inevitable offshoot from my long-established interest in chronometric hygiene, or 'getting the dates right'. In this paper I attempt to illustrate that accurate dating matters, by discussing some examples of AMS dating projects with which I have been involved over the last six years or so. In relation to these projects, AMS has given us the ability to date sites which we could not before. It has enabled us to provide more detailed stratigraphies when datable materials are rare. It has allowed us to date materials we could not date before, such as rock art pigments. It has been able to provide indications of the degree of site disturbance in the absence of other obvious forms of evidence. And it has allowed us to assess claims for the antiquity of particular material cultural types and faunal introductions. (author). 41 refs

End-to-End Service Oriented Architectures (SOA) Security Project

Science.gov (United States)

2012-02-01

Java 6.0 (javax.ws) platform and deployed on boston.cs.purdue.edu. TB stores all data regarding sessions and services in a MySQL database, setup on...pointcut designators. JBoss AOP [JBO2] and AspectJ [ASP1] are powerful frameworks that implement AOP for Java programs. Its pointcut designators... hibernate cglib enhanced proxies <attribute name="Ignore">*$$EnhancerByCGLIB$$*</attribute> --> <attribute name="Optimized">true</attribute

Characterization and Reliability of Vertical N-Type Gallium Nitride Schottky Contacts

Science.gov (United States)

2016-09-01

ACKNOWLEDGMENTS Foremost, I would like to thank my wife, Melissa, with whom I have three wonderful children. Without her endless love , unwavering...conducting research in the lab and studying in the library, she cared for our children and created a loving home for our family. Her strength, passion...Online]. Available: http://ecee.colorado.edu/~bart/book/book/title.htm 78 [12] R. T. Tung, “The physics and chemistry of the Schottky barrier

Meeting the Challenge of Distributed Real-Time & Embedded (DRE) Systems

Science.gov (United States)

2012-05-10

replication • Dynamic resource management • Examples • W3C Web Services, CORBA Component Model & Object Services, Sun’s J2EE, Microsoft’s .NET, etc...System Middleware Infrastructure Mission Computing Services Model-driven engineering ( MDE ) •Apply MDE tools to • Model • Analyze • Synthesize...Pulse Rate GPS MyLocation Refresh Ready www.isis.vanderbilt.edu/ projects/mobies Applying MDE to Bold Stroke ANALYSIS TOOLS CODE GENERATORS Stateflow Real

Brownian motion, old and new, and Irwin's role in my academic life

Science.gov (United States)

Lindenberg, Katja

2015-03-01

Irwin Oppenheim's early work on Langevin equations, master equations, and Brownian motion was one of the earliest and strongest reasons for my change of direction from my PhD work in condensed matter theory to my later and lifelong interest in Brownian motion and, more broadly, statistical mechanics. I will talk about some of my most recent work on subdiffusion, a form of anomalous diffusion that describes random motions in crowded or disordered media where motions are hindered by the medium. On a personal note, I knew Irwin for decades, from the time before he had a family (he was a sworn bachelor...until he met his wife) until shortly before his death. For many years, first alone and then with family, Irwin would spend some portion of the cold Boston winter in warm La Jolla, and we would always get together during these visits. For a period of a number of years we decided to take advantage of these visits to write the definitive text in traditional Thermodynamics. We did not make it past about 2/3 of the project, but it was a great learning experience for me while it lasted. Irwin's knowledge and understanding of the subject were breathtaking.

What I wish I had in my stockroom

Science.gov (United States)

Sampere, Samuel

2015-12-01

Most new teachers walk into their new classroom territory and find at least some equipment. Perhaps there are items there that you don't recognize. One way to get those types of questions answered is to post a question and/or picture on the TAP-L (Teaching Apparatus List) listserv (see: http://www.pira-online.org for more information). Within a few short minutes, the sender will receive at least a couple of responses. But what if a new teacher walks into a totally empty prep room? Now that teacher is tasked with purchasing useful equipment, and we know that the opportunity for a similar acquisition in the near future is slim. So you better choose wisely! Whether my new stockroom is well equipped or completely empty, I would make sure to have the following six items in my arsenal.

我的寒假%My Winter Holidays

Institute of Scientific and Technical Information of China (English)

无

2008-01-01

@@ Winter holidays have about twenty days.During winter holidays, I do all kinds of interesting thing.I like climbing the hill,because it can make me heMthy.I like fishing,it can give me a lot of fun.I like visiting some places of interest, it can enlarge my knowledge.

40 CFR 63.2343 - What are my requirements for emission sources not requiring control?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 12 2010-07-01 2010-07-01 true What are my requirements for emission sources not requiring control? 63.2343 Section 63.2343 Protection of Environment ENVIRONMENTAL PROTECTION... (Non-Gasoline) What This Subpart Covers § 63.2343 What are my requirements for emission sources not...

Analysis of Motherly Love in Edgar Allan Poe's “to My Mother

OpenAIRE

Rusdi, Putra

2017-01-01

Project analisisMotherly Love in Edgar Allan Poe's “To My Mother” mengkaji unsur intrinsik dan konsep motherly love dalam puisi To My Motherkarya Edgar Allan Poe. Penulis menggunakan studi pustaka sebagai metode pengumpulan data dan informasi tentang objek penelitian melalui buku dan internet. Penulis menggunakan pendekatan psikologi sastra dengan teori cinta karya Erich Fromm untuk mengetahui cinta yang diberikan ibu kepada anak. Dari hasil analisis, penulis menemukan konsep cinta yang dibe...

Translating MyPlate into Food Selections that Meet Dietary Guidelines Recommendations

Directory of Open Access Journals (Sweden)

Jessica Bachman

2016-10-01

Full Text Available The objective was to determine if individuals could plan a diet that met the Dietary Guidelines (DG using MyPlate as a guide. Participants (n=73 were 38.9±17.0 years of age, with 97% being Non-Hispanic White, 95% having some college education, and Body Mass Index (BMI of 26.7±5.9. Participants used MyPlate to plan a one-day menu using food models. Nutrition literacy, nutrition scanning behavior, and nutrition information-seeking experience were assessed. Menus were analyzed using Nutrition Data Systems for Research and were compared to individualized DG recommendations. A multiple linear regression examined what characteristics predicted energy difference scores (difference between energy from menu and DG. Participant menus were lower in energy, grains, and dairy; and higher in fruits and vegetables than DGs (p < 0.001. The regression model was significant (R2 = 0.24; p < 0.01 with sex (B = -386.92; p < 0.05, BMI (B = 29.29; p < 0.05 with nutrition information-seeking experience (B = 44.90; p < 0.05 predicting energy difference score. Being male, having a higher BMI, and experiencing more frustration during nutrition informationseeking were associated with higher energy difference scores. It was challenging for this sample of well-educated individuals to make food selections that met the DGs using MyPlate. Extension professionals should not assume that consumers understand and can apply the key messages of MyPlate.

Functional dependency between the logistics security system and the MySAP ERP in metallurgy

Directory of Open Access Journals (Sweden)

P. Ranitović

2013-10-01

Full Text Available MySAP ERP - Enterprise Resource Planning (system - solution which provides a whole set of functions for the business analytics, finance, human resources management, logistics and corporate services has developed from SAP R/3. It is one of the main products of the SAP AG German multinational company and as such, it is a very important element of the international industrial and technological security system. By defining the functional dependency between the security systems (logistics security systems and the IT (My SAP ERP systems in metallurgy, a concept for designing MY SAP ERP system in metallurgic industry is defined, based on the security aspects.

12 CFR 563b.380 - May my employee stock ownership plan purchase conversion shares?

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false May my employee stock ownership plan purchase... THE TREASURY CONVERSIONS FROM MUTUAL TO STOCK FORM Standard Conversions Offers and Sales of Stock § 563b.380 May my employee stock ownership plan purchase conversion shares? (a) Your tax-qualified...

30 CFR 285.823 - Will MMS reimburse me for my expenses related to inspections?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Will MMS reimburse me for my expenses related... Conducted Under SAPs, COPs and GAPs Inspections and Assessments § 285.823 Will MMS reimburse me for my expenses related to inspections? Upon request, MMS will reimburse you for food, quarters, and...

Development of an omnidirectional Automated Guided Vehicle with MY3 wheels

Directory of Open Access Journals (Sweden)

Suyang Yu

2016-03-01

Full Text Available This paper presents an omnidirectional Automated Guided Vehicle (AGV with a novel omnidirectional wheel named MY3 wheel. Due to the special structure and material of the MY3 wheel, the AGV has full three DOFs in the motion plane and good capabilities of load carrying and slip resisting. In addition, the kinematic model of the AGV is derived, and the guiding method that can make the AGV to follow a specified path is established. Finally, experiments are performed to verify the kinematic model and guiding method.

Ympäristömyötäinen tekstiilituotemallisto lapsille

OpenAIRE

Jääskeläinen, Heidi

2009-01-01

Opinnäytetyön tavoitteena oli tarkastella tekstiilien ympäristömyötäistä suunnittelua ja luoda sen mukainen uniikki tekstiilituotemallisto lapsille. Tuotteet suunniteltiin opintojen päätyttyä aloitettavan yritystoiminnan alkumallistoksi. Opinnäytetyön teoriaosuus jakautuu kolmeen osaan: ympäristömyötäiseen suunnitteluun, tuotesuunnitteluun ja tuotannonsuunnitteluun. Kutakin teoriaosuutta käsitellään opinnäytetyön suunnitteluprojektin näkökulmasta. Opinnäytetyön yhteydessä toteutettiin päi...

Can Glucosamine Supplements Protect My Knee Cartilage from Osteoarthritis?

Science.gov (United States)

... cartilage in osteoarthritis? Can glucosamine supplements protect my knee cartilage from osteoarthritis? Answers from Brent A. Bauer, M.D. Study results on this question have been mixed, with some suggesting possible ...

The reliability of vertical jump tests between the Vertec and My Jump phone application.

Science.gov (United States)

Yingling, Vanessa R; Castro, Dimitri A; Duong, Justin T; Malpartida, Fiorella J; Usher, Justin R; O, Jenny

2018-01-01

The vertical jump is used to estimate sports performance capabilities and physical fitness in children, elderly, non-athletic and injured individuals. Different jump techniques and measurement tools are available to assess vertical jump height and peak power; however, their use is limited by access to laboratory settings, excessive cost and/or time constraints thus making these tools oftentimes unsuitable for field assessment. A popular field test uses the Vertec and the Sargent vertical jump with countermovement; however, new low cost, easy to use tools are becoming available, including the My Jump iOS mobile application (app). The purpose of this study was to assess the reliability of the My Jump relative to values obtained by the Vertec for the Sargent stand and reach vertical jump (VJ) test. One hundred and thirty-five healthy participants aged 18-39 years (94 males, 41 females) completed three maximal Sargent VJ with countermovement that were simultaneously measured using the Vertec and the My Jump . Jump heights were quantified for each jump and peak power was calculated using the Sayers equation. Four separate ICC estimates and their 95% confidence intervals were used to assess reliability. Two analyses (with jump height and calculated peak power as the dependent variables, respectively) were based on a single rater, consistency, two-way mixed-effects model, while two others (with jump height and calculated peak power as the dependent variables, respectively) were based on a single rater, absolute agreement, two-way mixed-effects model. Moderate to excellent reliability relative to the degree of consistency between the Vertec and My Jump values was found for jump height (ICC = 0.813; 95% CI [0.747-0.863]) and calculated peak power (ICC = 0.926; 95% CI [0.897-0.947]). However, poor to good reliability relative to absolute agreement for VJ height (ICC = 0.665; 95% CI [0.050-0.859]) and poor to excellent reliability relative to absolute agreement for peak power

40 CFR 63.1562 - What parts of my plant are covered by this subpart?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 12 2010-07-01 2010-07-01 true What parts of my plant are covered by... What parts of my plant are covered by this subpart? (a) This subpart applies to each new, reconstructed...-regenerative, cyclic, or continuous processes) that are associated with regeneration of the catalyst used in...

30 CFR 250.135 - What will MMS do if my operating performance is unacceptable?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What will MMS do if my operating performance is....135 What will MMS do if my operating performance is unacceptable? If your operating performance is unacceptable, MMS may disapprove or revoke your designation as operator on a single facility or multiple...

30 CFR 250.133 - Will MMS reimburse me for my expenses related to inspections?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Will MMS reimburse me for my expenses related... Inspection of Operations § 250.133 Will MMS reimburse me for my expenses related to inspections? Upon request, MMS will reimburse you for food, quarters, and transportation that you provide for MMS representatives...

The development of an electronic business based on the MySQL technology

Directory of Open Access Journals (Sweden)

Andreea IONESCU

2011-09-01

Full Text Available This article aims to demonstrate the importance of using relational database management system in working with web applications. We chose MySQL technology like representative relational database management system because has: portability, scalability, speed, is easy to use, is open source, is widely used by web developers and provides good security. We watched the analysis of an electronic business. We also presented the technologies that we have used: PHP, MySQL, HTML, CSS.

Personalisatie in academische bibliotheeksystemen. - II: MyLibrary voorbij

NARCIS (Netherlands)

Hunsucker, R.L.

2005-01-01

Personalisation in academic library systems - II: Beyond MyLibrary The academic libraries' attempt to 'personalise' tracking down and accessing relevant literature and information sources developed into an undeniably meagre performance. So wrote R.L. Hunsucker in the first part of his contribution

Transfer of information from personal health records: a survey of veterans using My HealtheVet.

Science.gov (United States)

Turvey, Carolyn L; Zulman, Donna M; Nazi, Kim M; Wakefield, Bonnie J; Woods, Susan S; Hogan, Timothy P; Weaver, Frances M; McInnes, Keith

2012-03-01

Personal health records provide patients with ownership of their health information and allow them to share information with multiple healthcare providers. However, the usefulness of these records relies on patients understanding and using their records appropriately. My HealtheVet is a Web-based patient portal containing a personal health record administered by the Veterans Health Administration. The goal of this study was to explore veterans' interest and use of My HealtheVet to transfer and share information as well as to identify opportunities to increase veteran use of the My HealtheVet functions. Two waves of data were collected in 2010 through an American Customer Satisfaction Index Web-based survey. A random sample of veterans using My HealtheVet was invited to participate in the survey conducted on the My HealtheVet portal through a Web-based pop-up browser window. Wave One results (n=25,898) found that 41% of veterans reported printing information, 21% reported saving information electronically, and only 4% ever sent information from My HealtheVet to another person. In Wave Two (n=18,471), 30% reported self-entering medication information, with 18% sharing this information with their Veterans Affairs (VA) provider and 9.6% sharing with their non-VA provider. Although veterans are transferring important medical information from their personal health records, increased education and awareness are needed to increase use. Personal health records have the potential to improve continuity of care. However, more research is needed on both the barriers to adoption as well as the actual impact on patient health outcomes and well-being.

My Road to Transform Faulting 1963; Long-Term Precursors to Recent Great Earthquakes

Science.gov (United States)

Sykes, L. R.

2017-12-01

My road to plate tectonics started serendipitously in 1963 in a remote area of the southeast Pacific when I was studying the propagation of short-period seismic surface waves for my PhD. The earthquakes I used as sources were poorly located. I discovered that my relocated epicenters followed the crest of the East Pacific Rise but then suddenly took a sharp turn to the east at what I interpreted to be a major fracture zone 1000 km long before turning again to the north near 55 degrees south. I noted that earthquakes along that zone only occurred between the two ridge crests, an observation Tuzo Wilson used to develop his hypothesis of transform faulting. Finding a great, unknown fracture zone led me to conclude that work on similar faults that intersect the Mid-Oceanic Ridge System was more important than my study of surface waves. I found similar great faults over the next two years and obtained refined locations of earthquakes along several island arcs. When I was in Fiji and Tonga during 1965 studying deep earthquakes, James Dorman wrote to me about Wilson's paper and I thought about testing his hypothesis. I started work on it the spring of 1966 immediately after I learned about the symmetrical "magic magnetic anomaly profile" across the East Pacific Rise of Pitman and Heirtzler. I quickly obtained earthquake mechanisms that verified the transform hypothesis and its related concepts of seafloor spreading and continental drift. As an undergraduate in the late 1950s, my mentor told me that respectable young earth scientists should not work on vague and false mobilistic concepts like continental drift since continents cannot plow through strong oceanic crust. Hence, until spring 1966, I did not take continental drift seriously. The second part of my presentation involves new evidence from seismology and GPS of what appear to be long-term precursors to a number of great earthquakes of the past decade.

The Third Wave of Democratization in Indonesia

Science.gov (United States)

2000-03-01

Dewan Perwakilan Rakyat (House of the Representatives) augmented by delegates from the regional territories and the groups in accordance with...unlimited THE THIRD WAVE OF DEMOCRATIZATION IN INDONESIA Azizan bin Md Delin Lieutenant Colonel, Malaysian Army LL B. (Hons), UiTM, Malaysia , 1996...Article 2(1) of the 1945 Constitution reads: "The Majelis Permusyawaratan Rakyat (People’s Consultative Assembly) shall consist of members of the

40 CFR 1051.515 - How do I test my fuel tank for permeation emissions?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false How do I test my fuel tank for... Procedures § 1051.515 How do I test my fuel tank for permeation emissions? Measure permeation emissions by weighing a sealed fuel tank before and after a temperature-controlled soak. (a) Preconditioning fuel soak...

40 CFR 141.551 - What strengthened combined filter effluent turbidity limits must my system meet?

Science.gov (United States)

2010-07-01

... effluent turbidity limits must my system meet? 141.551 Section 141.551 Protection of Environment... Effluent Requirements § 141.551 What strengthened combined filter effluent turbidity limits must my system meet? Your system must meet two strengthened combined filter effluent turbidity limits. (a) The first...

MyD88-dependent dendritic and epithelial cell crosstalk orchestrates immune responses to allergens.

Science.gov (United States)

Thomas, S Y; Whitehead, G S; Takaku, M; Ward, J M; Xu, X; Nakano, K; Lyons-Cohen, M R; Nakano, H; Gowdy, K M; Wade, P A; Cook, D N

2018-05-01

Sensitization to inhaled allergens is dependent on activation of conventional dendritic cells (cDCs) and on the adaptor molecule, MyD88. However, many cell types in the lung express Myd88, and it is unclear how signaling in these different cell types reprograms cDCs and leads to allergic inflammation of the airway. By combining ATAC-seq with RNA profiling, we found that MyD88 signaling in cDCs maintained open chromatin at select loci even at steady state, allowing genes to be rapidly induced during allergic sensitization. A distinct set of genes related to metabolism was indirectly controlled in cDCs through MyD88 signaling in airway epithelial cells (ECs). In mouse models of asthma, Myd88 expression in ECs was critical for eosinophilic inflammation, whereas Myd88 expression in cDCs was required for Th17 cell differentiation and consequent airway neutrophilia. Thus, both cell-intrinsic and cell-extrinsic MyD88 signaling controls gene expression in cDCs and orchestrates immune responses to inhaled allergens.

50 CFR 86.44 - What are my allowable costs?

Science.gov (United States)

2010-10-01

...) PROGRAM Funding Availability § 86.44 What are my allowable costs? (a) The State may spend grant funds to pay only costs that are necessary and reasonable to accomplish the approved grant objectives. Grant...

40 CFR 35.4045 - What requirements must my group meet as a TAG recipient?

Science.gov (United States)

2010-07-01

... for the purpose of participating in decision making at the Superfund site for which we provide a TAG... 40 Protection of Environment 1 2010-07-01 2010-07-01 false What requirements must my group meet as... Responsibilities As A Tag Recipient § 35.4045 What requirements must my group meet as a TAG recipient? Your group...

30 CFR 285.601 - When am I required to submit my plans to MMS?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When am I required to submit my plans to MMS... Information Requirements § 285.601 When am I required to submit my plans to MMS? Your plan submission...) You must provide sufficient data and information with your COP for MMS to complete the needed reviews...

30 CFR 254.7 - How do I submit my response plan to the MMS?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I submit my response plan to the MMS... do I submit my response plan to the MMS? You must submit the number of copies of your response plan that the appropriate MMS regional office requires. If you prefer to use improved information technology...

30 CFR 285.510 - May MMS reduce or waive my lease or grant payments?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false May MMS reduce or waive my lease or grant... Financial Assurance Requirements Payments § 285.510 May MMS reduce or waive my lease or grant payments? (a) The MMS Director may reduce or waive the rent or operating fee or components of the operating fee...

Development of My Footprint Calculator

Science.gov (United States)

Mummidisetti, Karthik

The Environmental footprint is a very powerful tool that helps an individual to understand how their everyday activities are impacting environmental surroundings. Data shows that global climate change, which is a growing concern for nations all over the world, is already affecting humankind, plants and animals through raising ocean levels, droughts & desertification and changing weather patterns. In addition to a wide range of policy measures implemented by national and state governments, it is necessary for individuals to understand the impact that their lifestyle may have on their personal environmental footprint, and thus over the global climate change. "My Footprint Calculator" (myfootprintcalculator.com) has been designed to be one the simplest, yet comprehensive, web tools to help individuals calculate and understand their personal environmental impact. "My Footprint Calculator" is a website that queries users about their everyday habits and activities and calculates their personal impact on the environment. This website was re-designed to help users determine their environmental impact in various aspects of their lives ranging from transportation and recycling habits to water and energy usage with the addition of new features that will allow users to share their experiences and their best practices with other users interested in reducing their personal Environmental footprint. The collected data is stored in the database and a future goal of this work plans to analyze the collected data from all users (anonymously) for developing relevant trends and statistics.

Decreased serum level of HMGB1 and MyD88 during human aging progress in healthy individuals.

Science.gov (United States)

Fu, Guo-Xiang; Chen, Alex F; Zhong, Yuan; Zhao, Jian; Gu, Ying-Jia

2016-04-01

Previous studies have suggested that high mobility group box-1 protein (HMGB1) binds to the toll-like receptor 4 (TLR4) signaling mediates the progression of various inflammatory diseases. But the roles of HMGB1 and TLR4 in aging remain poorly unknown. In this study, we aimed to investigate the serum levels of HMGB1 and myeloid differentiation factor 88 (MyD88), which is one of TLR4's intracellular adaptor proteins during human aging process and their relevance with cathepsin B (CTSB). This research was conducted using the blood samples provided by healthy people (n = 90, 63 men and 27 women). Subjects were subdivided into groups with respect to age: young (about 25 years old, n = 30), middle age (about 40 years old, n = 30), and aged (above 65 years old, n = 30). Altered serum levels of HMGB1, MyD88 and CTSB were measured using an enzyme-linked immunosorbent assay. The serum levels of HMGB1 and MyD88 were significantly decreased in the aged group compared with those in the young group. Linear regression analysis showed that HMGB1 and MyD88 positively correlated with CTSB among the whole healthy people. A negative correlation was determined between MyD88 and age. The serum levels of HMGB1 and MyD88 significantly decreased with age. MyD88, but not HMGB1, was negatively correlated with age.

MyOSD 2014: Evaluating Oceanographic Measurements Contributed by Citizen Scientists in Support of Ocean Sampling Day

Directory of Open Access Journals (Sweden)

Julia Schnetzer

2015-11-01

Full Text Available The first Ocean Sampling Day (OSD took place on June 21, 2014. In a coordinated effort, an internationally distributed group of scientists collected samples from marine surface waters in order to study microbial diversity on a single day with global granularity. Concurrently, citizen scientists enriched the OSD initiative through the MyOSD project, providing additional oceanographic measurements crucial to the contextualization of microbial diversity. Clear protocols, a user-friendly smartphone application, and an online web-form guided citizens in accurate data acquisition, promoting quality submissions to the project’s information system. To evaluate the coverage and quality of MyOSD data submissions, we compared the sea surface temperature measurements acquired through OSD, MyOSD, and automatic in situ systems and satellite measurements. Our results show that the quality of citizen-science measurements was comparable to that of scientific measurements. As 79% of MyOSD measurements were conducted in geographic areas not covered by automatic in situ or satellite measurement, citizen scientists contributed significantly to worldwide oceanographic data gathering. Furthermore, survey results indicate that participation in MyOSD made citizens feel more engaged in ocean issues and may have increased their environmental awareness and ocean literacy.

Mississippi CaP HBCU Undergraduate Research Training Program

Science.gov (United States)

2016-09-01

creativity . Working in the field of prostate cancer has opened my mind to different risk factors of this disease, specifically old age and being of...5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Christian Gomez, Ph.D. 5d. PROJECT NUMBER E-Mail: crgomez@umc.edu 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7...Health Sciences related programs; 2 trainees are hired employees ; 8 trainees are currently pursuing graduation; 14 meeting presentations in the poster

DrugMetZ DB: an anthology of human drug metabolizing Chytochrome P450 enzymes.

Science.gov (United States)

Antony, Tresa Remya Thomas; Nagarajan, Shanthi

2006-11-14

Understandings the basics of Cytochrome P450 (P450 or CYP) will help to discern drug metabolism. CYP, a super-family of heme-thiolate proteins, are found in almost all living organisms and is involved in the biotransformation of a diverse range of xenobiotics, therapeutic drugs and toxins. Here, we describe DrugMetZ DB, a database for CYP metabolizing drugs. The DB is implemented in MySQL, PHP and HTML. www.bicpu.edu.in/DrugMetZDB/

myPhyloDB: a local web server for the storage and analysis of metagenomics data

Science.gov (United States)

myPhyloDB is a user-friendly personal database with a browser-interface designed to facilitate the storage, processing, analysis, and distribution of metagenomics data. MyPhyloDB archives raw sequencing files, and allows for easy selection of project(s)/sample(s) of any combination from all availab...

40 CFR 1048.410 - How must I select, prepare, and test my in-use engines?

Science.gov (United States)

2010-07-01

... my in-use engines? 1048.410 Section 1048.410 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW, LARGE NONROAD SPARK-IGNITION ENGINES Testing In-use Engines § 1048.410 How must I select, prepare, and test my in-use engines? (a) You...

“Because She Is My Teacher”

Institute of Scientific and Technical Information of China (English)

1998-01-01

IT was in late autumn when my engineering corps sent me to the Bayinbuluk Pasture deep in the Tianshan Mountains to learn how to play tumbubra, a traditional gourdshaped string instrument played by ethnic peoples in Xinjiang Uygur Autonomous Region. In order to rehearse for a performance of storytelling accompanied by tumbubra, I was to learn how to play the instrument from a Kazak folk artist, Uncle Aken. Three doctors and nurses from the

MyView2, a new visualization software tool for analysis of LHD data

International Nuclear Information System (INIS)

Moon, Chanho; Yoshinuma, Mikirou; Emoto, Masahiko; Ida, Katsumi

2016-01-01

The Large Helical Device (LHD) at the National Institute for Fusion Science (NIFS) is the world’s largest superconducting helical fusion device, providing a scientific research center to elucidate important physics research such as plasma transport, turbulence dynamics, and other topics. Furthermore, many types of advanced diagnostic devices are used to measure the confinement plasma characteristics, and these valuable physical data are registered over the 131,000 discharges in the LHD database. However, it is difficult to investigate the experimental data even though much physical data has been registered. In order to improve the efficiency for investigating plasma physics in LHD, we have developed a new data visualization software, MyView2, which consists of Python-based modules that can be easily set up and updated. MyView2 provides immediate access to experimental results, cross-shot analysis, and a collaboration point for scientific research. In particular, the MyView2 software is a portable structure for making viewable LHD experimental data in on- and off-site web servers, which is a capability not previously available in any general use tool. We will also discuss the benefits of using the MyView2 software for in-depth analysis of LHD experimental data.

My Folkloristic History of the Việt Nam War: A Non-communist Experience

Directory of Open Access Journals (Sweden)

Long S. Le

2013-01-01

Full Text Available Like many families who were on the “wrong” side of the Việt Nam war, my family history has effectively been “displaced” from official discourse in Việt Nam when the country was “reunified” in 1975, as well as in the discourse of public history in the U.S. which has overwhelmingly emphasized the “lessons” of the “American Experience” in Việt Nam. Using my family history as an index of historical processes, I hope to introduce windows on the continuities of what noncommunist Vietnamese do and think. My family folklore is utilized as a way to create opportunities for other non-communist Vietnamese here and elsewhere to connect, articulate, or remind them of a pattern from the past that can provide a contemporary coherence with an ethic workable for the future.

The COST example for outreach to the general public: I love my Sun

Science.gov (United States)

Tulunay, Yurdanur; Crosby, Norma Bock; Tulunay, Ersin; Calders, Stijn; Parnowski, Aleksei; Sulic, Desanka

2013-01-01

It is important to educate children about the important role that the Sun has in their lives. This paper presents an educational outreach tool entitled "I Love My Sun" that has been developed for school children in the approximate age range of 7 through 11 years. The main objective of this tool is to make children aware of space weather, the Sun, Sun-Earth relations and how they, the children, are part of this global picture. Children are given a lecture about the Sun. The lecture is preceded and followed by the children drawing a picture of the Sun. In this paper the background behind the "I Love My Sun" initiative is given and it is described how to perform an "I Love My Sun". The main results from events in Turkey, Belgium, Ukraine and Serbia are presented.

41 CFR 302-3.218 - Are there any special circumstances when my agency may authorize me travel and transportation...

Science.gov (United States)

2010-07-01

... circumstances when my agency may authorize me travel and transportation expenses for my tour renewal travel in... agency may authorize me travel and transportation expenses for my tour renewal travel in Alaska or Hawaii? Other than as specified in §§ 302-3.209 through 302-3.226, your agency head will only authorize travel...

Christian ethics: on the difficult dialectics between faith and ethics. http://dlibrary.acu.edu.au/research/theology/ejournal/aejt_2/Jan_Jans.htm

NARCIS (Netherlands)

Jans, J.M.N.E.

2004-01-01

The thesis of this paper is that Christian theological ethics or moral theology is only possible for those who conceive such a conflict as an opportunity for a fruitful dialectics between faith and ethics. Furthermore, it would be my thesis that experience and practical reflection in the area of

12 CFR 502.75 - What if I do not pay my fees on time?

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false What if I do not pay my fees on time? 502.75 Section 502.75 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY ASSESSMENTS AND FEES Fees § 502.75 What if I do not pay my fees on time? (a) Interest. An examination or investigation...

Distracted: Academic Performance Differences between Teen Users and Non-Users of MySpace and other Communication Technology

Directory of Open Access Journals (Sweden)

Tamyra A. Pierce

2008-06-01

Full Text Available This study examined the differences in academic performance between teen users and non-users of various communication technologies. Participants included 517 high school students who completed a self-report survey. The results revealed that approximately 3/4 of the teens had a MySpace account and a cell phone and more than 1/2 had an IM account. Results also showed that those who had a MySpace account, cell phone and IM had signifi cantly lower grades than those who did not. Results also revealed that teens who used their MySpace, cell phone and IM while doing their homework reported having lower grades than those who did not use the technology while doing their homework. In addition, those who put off doing their homework to spend time on MySpace also reported lower grades than those who did not put off doing their homework to spend time with MySpace. Finally, results showed that 28% text messaged during class from always to frequently, and 5% reported text messaging during an exam from always to frequently.

32 CFR 37.875 - Should my TIA include a provision concerning foreign access to technology?

Science.gov (United States)

2010-07-01

... 32 National Defense 1 2010-07-01 2010-07-01 false Should my TIA include a provision concerning... Related to Other Administrative Matters Intellectual Property § 37.875 Should my TIA include a provision... provision in the TIA that addresses foreign access to technology developed under the TIA. (b) The provision...

Weighted Moore–Penrose generalized matrix inverse: MySQL vs ...

Indian Academy of Sciences (India)

Danijela Milošević

database system, MySQL and NoSQL, key value store system, ApacheCassandra, on the database layer. The ..... Memory (RAM): 2940MB; System type: 32-bit Operating .... [3] Elmasri R and Navathe SB 2003 Fundamentals of database.

NARRATIVE: A short history of my life in science A short history of my life in science

Science.gov (United States)

Manson, Joseph R.

2010-08-01

I was certainly surprised, and felt extremely honored, when Salvador Miret-Artés suggested that he would like to organize this festschrift. Before that day I never anticipated that such an honor would come to me. I would like to thank Salvador for the large amount of time and work he has expended in organizing this special issue, the Editors of Journal of Physics: Condensed Matter for making it possible, and also the contributing authors for their efforts. My family home was outside of Petersburg, Virginia in Dinwiddie County in an area that was, during my youth, largely occupied by small farms. This is a region rich in American history and our earliest ancestors on both sides of the family settled in this area, beginning in the decade after the first Virginia settlement in Jamestown. My father was an engineer and my mother was a former school teacher, and their parents were small business owners. From earliest memories I recall being interested in finding out how things worked and especially learning about the wonders of nature. These interests were fostered by my parents who encouraged such investigations during long walks, visits to friends and relatives, and trips to museums. However, my earliest memory of wanting to become a scientist is associated with a Christmas gift of a chemistry set when I was about ten years old. I was absolutely fascinated by the amazing results that could be achieved with simple chemical reactions and realized then that I wanted to do something in life that would be associated with science. The gift of that small chemistry set developed over the next few years into a serious interest in chemistry, and throughout my junior high-school years I spent nearly all the money I earned doing odd jobs for neighbors on small laboratory equipment and chemical supplies, eventually taking over our old abandoned chicken house and turning it into a small chemistry lab. I remember being somewhat frustrated at the limits, mainly financial, that kept

Free Speech in a MySpace World

Science.gov (United States)

Baule, Steven M.; Kriha, Darcy L.

2008-01-01

In the potential shadow of a "Bong Hits for Jesus" banner, complicated student speech and discipline issues arise almost daily on the Internet. Whether it is a mock MySpace page set up to make fun of a teacher or a direct threat to an assistant principal, it is often unclear exactly where school ground discipline ends and student free speech…

41 CFR 302-3.419 - For what property will my agency pay property management services?

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false For what property will my agency pay property management services? 302-3.419 Section 302-3.419 Public Contracts and Property....419 For what property will my agency pay property management services? Your agency will only pay for...

31 CFR 370.11 - What must my financial institution do when it receives a payment?

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false What must my financial institution do... What must my financial institution do when it receives a payment? An institution which receives a... which the institution is located, payment will be made on the next-succeeding business day. If the...

Uses and Effects of MySpace among Christian Teens and Young Adult

OpenAIRE

Michael S. Jeffress

2015-01-01

In 2008, MySpace was one of the world’s top Internet destinations.  Behind only Google and Yahoo in Internet traffic in America, it was the most popular social networking site (SNS) with some 300,000 profiles being added daily. Although MySpace would soon be supplanted in the SNS world by the likes of Facebook and Twitter, it still has over 50 million unique users each month and over 300,000 video views monthly.  Research performed during the period of its height in popularity is still valuab...

Butter vs. Margarine: Which Is Better for My Heart?

Science.gov (United States)

... Lifestyle Nutrition and healthy eating Which spread is better for my heart — butter or margarine? Answers from Katherine Zeratsky, R.D., ... answers/butter-vs-margarine/faq-20058152 . Mayo Clinic Footer Legal Conditions and Terms Any use of this ...

The MY NASA DATA Project: Tools and a Collaboration Space for Knowledge Discovery

Science.gov (United States)

Chambers, L. H.; Alston, E. J.; Diones, D. D.; Moore, S. W.; Oots, P. C.; Phelps, C. S.

2006-05-01

The Atmospheric Science Data Center (ASDC) at NASA Langley Research Center is charged with serving a wide user community that is interested in its large data holdings in the areas of Aerosols, Clouds, Radiation Budget, and Tropospheric Chemistry. Most of the data holdings, however, are in large files with specialized data formats. The MY NASA DATA (mynasadata.larc.nasa.gov) project began in 2004, as part of the NASA Research, Education, and Applications Solutions Network (REASoN), in order to open this important resource to a broader community including K-12 education and citizen scientists. MY NASA DATA (short for Mentoring and inquirY using NASA Data on Atmospheric and earth science for Teachers and Amateurs) consists of a web space that collects tools, lesson plans, and specially developed documentation to help the target audience more easily use the vast collection of NASA data about the Earth System. The core piece of the MY NASA DATA project is the creation of microsets (both static and custom) that make data easily accessible. The installation of a Live Access Server (LAS) greatly enhanced the ability for teachers, students, and citizen scientists to create and explore custom microsets of Earth System Science data. The LAS, which is an open source software tool using emerging data standards, also allows the MY NASA DATA team to make available data on other aspects of the Earth System from collaborating data centers. We are currently working with the Physical Oceanography DAAC at the Jet Propulsion Laboratory to bring in several parameters describing the ocean. In addition, MY NASA DATA serves as a central space for the K-12 community to share resources. The site already includes a dozen User-contributed lesson plans. This year we will be focusing on the Citizen Science portion of the site, and will be welcoming user-contributed project ideas, as well as reports of completed projects. An e-mentor network has also been created to involve a wider community in

Strategic planning for MyRA performance: A causal loop diagram approach

Science.gov (United States)

Abidin, Norhaslinda Zainal; Zaibidi, Nerda Zura; Karim, Khairah Nazurah

2017-10-01

The nexus of research and innovation in higher education are continually receiving worldwide priority attention. Hence, Malaysia has taken its move to enhance public universities as a center of excellence by introducing the status of Research University (RU). To inspire all universities towards becoming a research university, The Ministry of Higher Education (MoHE) had revised an assessment called Malaysian Research Assessment Instrument (MyRA) to evaluate the performance of existence RUs, and other potential higher education institutions. The available spreadsheet tool to access MyRA performance is inadequate to support strategic planning. Since, higher education management is a complex system, in which components and their interactions are ever changing over time, there is a need to for an efficient approach to investigate system behavior and devise research management policies for the benefit of the institution itself and the higher education system. In this paper, we proposed a system dynamics simulation model to evaluate the impact of policies for obtaining the highest performance in MyRA assessment. Causal loop diagram is developed to investigate the relationship of various elements in research management, their inter-relationship that link together and their evolution of behavior over time.

Puzzling Pieces and Spiders' Webs: A Narrative about My Personal Journey to Teaching

Science.gov (United States)

Burns, Stephanie

2017-01-01

I wrote the following paper upon completing my semester as a Student Teacher at an elementary school in a mid-size Midwestern university town. The goal in writing and presenting this paper was to select a focus area of growth throughout my time in the education program, considering how I've developed, what I've learned and where I hope to go as I…

The Representation of Muslim American in Karan Johar's Movie My Name is Khan

OpenAIRE

PUTRI, SARAH WIDITA

2015-01-01

Keywords: Representation, Muslim American, My Name is Khan. Literature always appear with the story about something that reflects or describes the human life. Movie can be a medium of communication. Movie is one of mass media that deliver some minds, aspiration, and controversial issue. My Name is Khan presents the reflection in United States about how American treat Muslim unfairly where the United States is the country of various religion, ethnics, and uphold the human rights. Directed by ...

The COST example for outreach to the general public: I love my Sun

Directory of Open Access Journals (Sweden)

Sulic Desanka

2013-01-01

Full Text Available It is important to educate children about the important role that the Sun has in their lives. This paper presents an educational outreach tool entitled “I Love My Sun” that has been developed for school children in the approximate age range of 7 through 11 years. The main objective of this tool is to make children aware of space weather, the Sun, Sun-Earth relations and how they, the children, are part of this global picture. Children are given a lecture about the Sun. The lecture is preceded and followed by the children drawing a picture of the Sun. In this paper the background behind the “I Love My Sun” initiative is given and it is described how to perform an “I Love My Sun”. The main results from events in Turkey, Belgium, Ukraine and Serbia are presented.

Real Time In Situ data management system for EuroGOOS: A ROOSes-MyOcean joint effort

Science.gov (United States)

Pouliquen, S.; Carval, T.; Loubrieu, T.; von Schuckmann, K.; Wehde, H.; SjurRingheim, L.; Hammarklint, T.; Harman, A.; Soetje, K.; Gies, T.; de Alfonso, M.; Perivoliotis, L.; Kassis, D.; Marinova, V.

2012-04-01

MyOcean is the implementation project of the GMES Marine Core Service, that develop the first concerted and integrated pan-European capacity for Ocean Monitoring and Forecasting. Within this project, the in-situ Thematic Assembly Centre (in-situ TAC) of MyOcean is a distributed service integrating data from different sources for operational oceanography needs. The MyOcean in-situ TAC is collecting and carrying out quality control in a homogeneous manner on data from outside MyOcean data providers, especially EuroGOOSparners, to fit the needs of internal and external users. It provides access to integrated datasets of core parameters for initialization, forcing, assimilation and validation of ocean numerical models. Since the primary objective of MyOcean is to forecast ocean state, the initial focus is on observations from automatic observatories at sea (e.g. floats, buoys, gliders, ferrybox, drifters, SOOP) which are transmitted in real-time to the shore. The second objective is to set up a system for re-analysis purposes that integrate data over the past 20 years. The global and regional portals set up by the INS-TAC are extended by the EuroGOOS ROOSES to integrate additionnal parameters important for downstream and national applications.

MyGeneFriends: A Social Network Linking Genes, Genetic Diseases, and Researchers.

Science.gov (United States)

Allot, Alexis; Chennen, Kirsley; Nevers, Yannis; Poidevin, Laetitia; Kress, Arnaud; Ripp, Raymond; Thompson, Julie Dawn; Poch, Olivier; Lecompte, Odile

2017-06-16

The constant and massive increase of biological data offers unprecedented opportunities to decipher the function and evolution of genes and their roles in human diseases. However, the multiplicity of sources and flow of data mean that efficient access to useful information and knowledge production has become a major challenge. This challenge can be addressed by taking inspiration from Web 2.0 and particularly social networks, which are at the forefront of big data exploration and human-data interaction. MyGeneFriends is a Web platform inspired by social networks, devoted to genetic disease analysis, and organized around three types of proactive agents: genes, humans, and genetic diseases. The aim of this study was to improve exploration and exploitation of biological, postgenomic era big data. MyGeneFriends leverages conventions popularized by top social networks (Facebook, LinkedIn, etc), such as networks of friends, profile pages, friendship recommendations, affinity scores, news feeds, content recommendation, and data visualization. MyGeneFriends provides simple and intuitive interactions with data through evaluation and visualization of connections (friendships) between genes, humans, and diseases. The platform suggests new friends and publications and allows agents to follow the activity of their friends. It dynamically personalizes information depending on the user's specific interests and provides an efficient way to share information with collaborators. Furthermore, the user's behavior itself generates new information that constitutes an added value integrated in the network, which can be used to discover new connections between biological agents. We have developed MyGeneFriends, a Web platform leveraging conventions from popular social networks to redefine the relationship between humans and biological big data and improve human processing of biomedical data. MyGeneFriends is available at lbgi.fr/mygenefriends. ©Alexis Allot, Kirsley Chennen, Yannis

Analysis of Personal Digital Library and MyLibrary%"Personal Digital Library"与"MyLibrary"辨析

Institute of Scientific and Technical Information of China (English)

秦飞飞

2011-01-01

学术界一些研究者认为"Personal Digital Library"与"MyLibrary"均可指个人数字图书馆.然而,两者是不同概念、特征及功能的事物.论文对两者的概念、研究现状及趋势作了详细的论述,旨在揭示这两种事物,为后续研究者提供借鉴.

40 CFR 63.1566 - What are my requirements for organic HAP emissions from catalytic reforming units?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 12 2010-07-01 2010-07-01 true What are my requirements for organic HAP emissions from catalytic reforming units? 63.1566 Section 63.1566 Protection of Environment... are my requirements for organic HAP emissions from catalytic reforming units? (a) What emission...

40 CFR 63.1567 - What are my requirements for inorganic HAP emissions from catalytic reforming units?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 12 2010-07-01 2010-07-01 true What are my requirements for inorganic HAP emissions from catalytic reforming units? 63.1567 Section 63.1567 Protection of Environment... are my requirements for inorganic HAP emissions from catalytic reforming units? (a) What emission...

40 CFR 62.15145 - What are the operating practice requirements for my municipal waste combustion unit?

Science.gov (United States)

2010-07-01

... requirements for my municipal waste combustion unit? 62.15145 Section 62.15145 Protection of Environment... Combustion Units Constructed on or Before August 30, 1999 Good Combustion Practices: Operating Requirements § 62.15145 What are the operating practice requirements for my municipal waste combustion unit? (a) You...

My City of Ruins: Bruce Springsteen e l’utopia fra le rovine

Directory of Open Access Journals (Sweden)

Enrico Botta

2011-09-01

Full Text Available The paper focuses on My City of Ruins, the song that Bruce Springsteen sang—ten days after the 09/11 terrorist attacks—for "America: A Tribute to Heroes" and that was released in the concept album The Rising in 2002. The essay aims to highlight how the song describes the post 09/11 New York City by opposing the themes of “ruins” and “utopia.” From a textual and musical point of view, My City of Ruins is, in fact, composed of a double structure that balances different feelings: the fear, pain, and loneliness of the victims, in the rock-blues first section; the faith, love, and hope, in the gospel second part. Furthermore, the paper tries to point out how My City of Ruins no longer describes the symbolic ruins of a foreign past—in line with the nineteenth and twentieth-century American cultural tradition of the Grand Tour—but defines the physical signs of a definitively collapsed “American dream,” which can survive only in a utopian and spiritual “Promised Land.”

MyD88 is crucial for the development of a protective CNS immune response to Toxoplasma gondii infection

Directory of Open Access Journals (Sweden)

Torres Marbel

2013-02-01

Full Text Available Abstract Background Toxoplasmosis is one of the most common parasitic infections in humans. It can establish chronic infection and is characterized by the formation of tissue cysts in the brain. The cysts remain largely quiescent for the life of the host, but can reactivate and cause life-threatening toxoplasmic encephalitis in immunocompromised patients, such as those with AIDS, neoplastic diseases and organ transplants. Toll-like receptor (TLR adaptor MyD88 activation is required for the innate sensing of Toxoplasma gondii. Mice deficient in MyD88 have defective IL-12 and Th1 effector responses, and are highly susceptible to the acute phase of T. gondii infection. However, the role of this signaling pathway during cerebral infection is poorly understood and requires examination. Method MyD88-deficient mice and control mice were orally infected with T. gondii cysts. Cellular and parasite infiltration in the peripheral organs and in the brain were determined by histology and immunohistochemistry. Cytokine levels were determined by ELISA and chemokine mRNA levels were quantified by real-time PCR (qPCR. Results Thirteen days after infection, a higher parasite burden was observed but there was no histological change in the liver, heart, lungs and small intestine of MyD88−/− and MyD88+/+ mice. However, MyD88−/− mice compared to MyD88+/+ mice were highly susceptible to cerebral infection, displayed high parasite migration to the brain, severe neuropathological signs of encephalitis and succumbed within 2 weeks of oral infection. Susceptibility was primarily associated with lower expression of Th1 cytokines, especially IL-12, IFN-γ and TNF-α, significant decrease in the expression of CCL3, CCL5, CCL7 and CCL19 chemokines, marked defect of CD8+ T cells, and infiltration of CD11b+ and F4/80+ cells in the brain. Conclusion MyD88 is essential for the protection of mice during the cerebral installation of T. gondii infection. These results

Experimental and natural infections in MyD88- and IRAK-4-deficient mice and humans

Science.gov (United States)

von Bernuth, Horst; Picard, Capucine; Puel, Anne; Casanova, Jean-Laurent

2013-01-01

Most Toll-like-receptors (TLRs) and interleukin-1 receptors (IL-1Rs) signal via myeloid differentiation primary response 88 (MyD88) and interleukin-1 receptor-associated kinase 4 (IRAK-4). The combined roles of these two receptor families in the course of experimental infections have been assessed in MyD88- and IRAK-4-deficient mice for almost fifteen years. These animals have been shown to be susceptible to 46 pathogens: 27 bacteria, 8 viruses, 7 parasites, and 4 fungi. Humans with inborn MyD88 or IRAK-4 deficiency were first identified in 2003. They suffer from naturally occurring life-threatening infections caused by a small number of bacterial species, although the incidence and severity of these infections decrease with age. Mouse TLR- and IL-1R-dependent immunity mediated by MyD88 and IRAK-4 seems to be vital to combat a wide array of experimentally administered pathogens at most ages. By contrast, human TLR- and IL-1R-dependent immunity mediated by MyD88 and IRAK-4 seems to be effective in the natural setting against only a few bacteria and is most important in infancy and early childhood. The roles of TLRs and IL-1Rs in protective immunity deduced from studies in mutant mice subjected to experimental infections should therefore be reconsidered in the light of findings for natural infections in humans carrying mutations as discussed in this review. PMID:23255009

MySQL based selection of appropriate indexing technique in ...

African Journals Online (AJOL)

Administrator

Keywords: B-tree indexing, MySQL, Support vector machine, Smart card. 1. ..... SVM are strong classifiers in the field of machine learning and we will be using ..... We acknowledge Mr. Abhishek Roy, student of NIT Surathkal for his help in the ...

45 CFR 630.400 - What are my responsibilities as a(n) National Science Foundation awarding official?

Science.gov (United States)

2010-10-01

....400 What are my responsibilities as a(n) National Science Foundation awarding official? As a(n... 45 Public Welfare 3 2010-10-01 2010-10-01 false What are my responsibilities as a(n) National Science Foundation awarding official? 630.400 Section 630.400 Public Welfare Regulations Relating to...

Productes d’informació de premsa nacionals (1). My News

OpenAIRE

Guallar, Javier

2009-01-01

Guide to My News, a press database and a clipping service of Spanish newspapers. The guide is a part of the course "The best digital information resources for journalism documentation" (Barcelona: Cobdc, 2009)

ESTminer: a Web interface for mining EST contig and cluster databases.

Science.gov (United States)

Huang, Yecheng; Pumphrey, Janie; Gingle, Alan R

2005-03-01

ESTminer is a Web application and database schema for interactive mining of expressed sequence tag (EST) contig and cluster datasets. The Web interface contains a query frame that allows the selection of contigs/clusters with specific cDNA library makeup or a threshold number of members. The results are displayed as color-coded tree nodes, where the color indicates the fractional size of each cDNA library component. The nodes are expandable, revealing library statistics as well as EST or contig members, with links to sequence data, GenBank records or user configurable links. Also, the interface allows 'queries within queries' where the result set of a query is further filtered by the subsequent query. ESTminer is implemented in Java/JSP and the package, including MySQL and Oracle schema creation scripts, is available from http://cggc.agtec.uga.edu/Data/download.asp agingle@uga.edu.

gestion d'une agence de voyage selon le modele client/serveur avec swing et mySQL

OpenAIRE

BELGACEM, Hicham; BOUAZZA, Mohammed Reda

2014-01-01

L’objectif de ce modeste travail est le développement d'une application Client/serveur pour la gestion d’une agence de voyage en se basant sur SWING et MySQL. Dans le premier chapitre de notre rapport nous avons présenté les outils misent en place pour la réalisation de notre application, en commençant par le langage Java utilisés sous Netbeans, MySQL pour la gestion de base de données et phpMyAdmin pour créer la BDD. Le deuxième chapitre est consacré à la présentation de notre...

Can anyone help me disseminate my body of nursing research?

Science.gov (United States)

Stockwell, Felicity

2013-04-03

More than 40 years ago, I researched the nurse-patient relationship in The Unpopular Patient. My research, particularly on unmet social needs, has led me to investigate the key issue of maternal-infant bonding.

20 CFR 404.337 - When does my entitlement to widow's and widower's benefits start and end?

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false When does my entitlement to widow's and widower's benefits start and end? 404.337 Section 404.337 Employees' Benefits SOCIAL SECURITY... does my entitlement to widow's and widower's benefits start and end? (a) We will find you entitled to...

My journey on breastfeeding: Autoethnographic challenge to low national prevalence

Directory of Open Access Journals (Sweden)

Diana Verónica Jiménez Cervantes

2016-11-01

Full Text Available In this article I offer a psychosocial reflection around breastfeeding and its scarce prevalence in Mexico. In my multiple role as mother-to-be, psychologist and researcher, I took part in a group, offered as a service by the socialized health organizations to Mexican mothers. In this autoethnography I analized my own pregnancy and maternity condition and compared it with the experiences of other mothers in varied wide variety of circumstances. I found that breastfeeding cannot be understood only as a mother-baby diad in a family environment but as a complex network of relationships and forces that range from national policy to the tastes and personal intentions of the mothers. Placing brestfeeding withing this perspective we can go forth on the road to explain and increase the extremely low present prevalences.

Introducción a phpMyAdmin (3/4)

OpenAIRE

Suárez Cueto, Armando

2012-01-01

Curso "Introducción al desarrollo web": inserción de datos, creación de una relación muchos a muchos (N:N), claves ajenas, integridad referencial, diseñador de phpMyAdmin. Más información: http://idesweb.es

'Electricity is running through my veins': DIE symbiose Zwischen ...

African Journals Online (AJOL)

'Electricity is running through my veins': the symbiosis between humankind and technology in Marshall McLuhan's media theory. In contrast to a widespread technical-mathematical media model that reduces electronic media to transmission channels, thereby making information into a quantifi able commodity, Canadian ...

My Work in the NASA Glenn History Office and Records Management Office

Science.gov (United States)

Mate, Robert C.

2004-01-01

This is my fourth summer working with my mentor, Kevin P. Coleman, who is the Center History Coordinator, Center Records Manager, and Center Forms Manager. I am working in the GRC History Office with some overlap in the Records Management Office. I have three major projects this summer. First, I am assisting in the documentation of historic facilities. Second, I am involved in a project to organize files and create an archives at Plum Brook Station. Third, I have helped the records management office with its inventory of stored records at Plum Brook. Also, I received an award this summer for research work I had done for NASA in the past. First, my primary project is to help assemble documentation for historic facilities at Glenn. This is somewhat of an extension of my project from last summer. Last summer, I worked to compile a complete list of all of NASA s historic sites and landmarks (as designated by the National Park Service, as well as several private organizations) throughout the country. Then, I briefly researched the significance of historic designation under federal law. Finally, I put my findings into a report which was submitted to NASA Headquarters. Upon review by the NASA History Office and several center-level history officials, it was decided that NASA should work to update its documentation of its historic sites and landmarks since some of the documentation was outdated or unavailable. Until recently, many project managers and facility managers working at historic facilities were not even aware that their surroundings had been designated as historic under federal law (most specifically, the National Historic Preservation Act of 1966 and its amendments). Therefore, they were unaware of the legal obligations for historic preservation. This summer, my project is to research some of Glenn s historic sites and landmarks in more detail. The goal is to put together a template for documenting historic NASA facilities. The hope is that this template of

41 CFR 102-118.80 - Who is responsible for keeping my agency's electronic commerce transportation billing records?

Science.gov (United States)

2010-07-01

... keeping my agency's electronic commerce transportation billing records? 102-118.80 Section 102-118.80... Transportation and Transportation Services § 102-118.80 Who is responsible for keeping my agency's electronic commerce transportation billing records? Your agency's internal financial regulations will identify...

Barack Obama’s Dreams from My Father and African American Literature

Directory of Open Access Journals (Sweden)

Daniel Stein

2011-09-01

Full Text Available This article provides a series of close readings of Barack Obama’s autobiography Dreams from My Father. It places the narrative within the history of African American literature and rhetoric and argues that Obama uses the text to create a life story that resonates with central concepts of African American selfhood and black male identity, including double consciousness, invisibility, and black nationalism. The article reads Dreams from My Father as an attempt to arrive at a state of “functional Blackness,” which moves away from questions of racial authenticity and identity politics but recognizes the narrative powers of African American literature to shape a convincing and appealing black self.

My Oar Keeps Breaking: How to Move Your Part of the Program Forward

Science.gov (United States)

2016-02-01

ship analogy. I had a whiteboard in my office. One day, I drew a large sailing ship with two masts and labeled the ship the S.S. Program. I drew...the journey over the edge. Finally, another drew a little boat popping up out of the water and labeled it the alternative to our program that the...that I needed to focus my energies on the part of the program I could control. 55 Defense AT&L: January–February 2016 moron! Of course you can’t

21 CFR 822.11 - What should I consider when designing my plan to conduct postmarket surveillance?

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false What should I consider when designing my plan to conduct postmarket surveillance? 822.11 Section 822.11 Food and Drugs FOOD AND DRUG ADMINISTRATION... Surveillance Plan § 822.11 What should I consider when designing my plan to conduct postmarket surveillance...

14 CFR 61.317 - Is my sport pilot certificate issued with aircraft category and class ratings?

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Is my sport pilot certificate issued with... GROUND INSTRUCTORS Sport Pilots § 61.317 Is my sport pilot certificate issued with aircraft category and class ratings? Your sport pilot certificate does not list aircraft category and class ratings. When you...

30 CFR 204.206 - What will MMS do when it receives my request for other relief?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What will MMS do when it receives my request... THE INTERIOR MINERALS REVENUE MANAGEMENT ALTERNATIVES FOR MARGINAL PROPERTIES Accounting and Auditing Relief § 204.206 What will MMS do when it receives my request for other relief? When MMS receives your...

MyD88 Adaptor Protein Is Required for Appropriate Hepcidin Induction in Response to Dietary Iron Overload in Mice

Directory of Open Access Journals (Sweden)

Antonio Layoun

2018-03-01

Full Text Available Iron homeostasis is tightly regulated to provide virtually all cells in the body, particularly red blood cells, with this essential element while defending against its toxicity. The peptide hormone hepcidin is central to the control of the amount of iron absorbed from the diet and iron recycling from macrophages. Previously, we have shown that hepcidin induction in macrophages following Toll-like receptor (TLR stimulation depends on the presence of myeloid differentiation primary response gene 88 (MyD88. In this study, we analyzed the regulation of iron metabolism in MyD88−/− mice to further investigate MyD88 involvement in iron sensing and hepcidin induction. We show that mice lacking MyD88 accumulate significantly more iron in their livers than wild-type counterparts in response to dietary iron loading as they are unable to appropriately control hepcidin levels. The defect was associated with inappropriately low levels of Smad4 protein and Smad1/5/8 phosphorylation in liver samples found in the MyD88−/− mice compared to wild-type mice. In conclusion, our results reveal a previously unknown link between MyD88 and iron homeostasis, and provide new insights into the regulation of hepcidin through the iron-sensing pathway.

Best Friends: Alliances, Friend Ranking, and the MySpace Social Network.

Science.gov (United States)

DeScioli, Peter; Kurzban, Robert; Koch, Elizabeth N; Liben-Nowell, David

2011-01-01

Like many topics of psychological research, the explanation for friendship is at once intuitive and difficult to address empirically. These difficulties worsen when one seeks, as we do, to go beyond "obvious" explanations ("humans are social creatures") to ask deeper questions, such as "What is the evolved function of human friendship?" In recent years, however, a new window into human behavior has opened as a growing fraction of people's social activity has moved online, leaving a wealth of digital traces behind. One example is a feature of the MySpace social network that allows millions of users to rank their "Top Friends." In this study, we collected over 10 million people's friendship decisions from MySpace to test predictions made by hypotheses about human friendship. We found particular support for the alliance hypothesis, which holds that human friendship is caused by cognitive systems that function to create alliances for potential disputes. Because an ally's support can be undermined by a stronger outside relationship, the alliance model predicts that people will prefer partners who rank them above other friends. Consistent with the alliance model, we found that an individual's choice of best friend in MySpace is strongly predicted by how partners rank that individual. © The Author(s) 2011.

My uncle used to watch television

CSIR Research Space (South Africa)

Smith, Andrew C

2010-09-01

Full Text Available to macular degeneration, an age-related illness characterized by a detached retina leading to complete blindness. He has been classified as legally blind. Using the multitude of remote-control devices is becoming an acute problem for my uncle. He has... to a radio station. Current radio designs present the user with a range of buttons, which can be depressed. Searching for a radio station is accomplished by depressing a specified button and listening to the audio while a circuit changes fre...

My IEP: A Student-Directed Individualized Education Program Model

Science.gov (United States)

Royer, David J.

2017-01-01

Students with disabilities need to be more involved in planning and presenting individualized education program (IEP) meetings, and teachers need an effective, efficient curriculum to teach students how. "My IEP" curriculum uses folding graphic organizers to teach students to self-direct IEP meetings, targeting self-advocacy and…

MyMoon: Engaging the “Missing Link” in Lunar Science Exploration through New Media

Science.gov (United States)

Shaner, A.; Shupla, C.; Shipp, S. S.; Eriksson, A.

2009-12-01

NASA’s new scientific exploration of the Moon, coupled with the public’s interest in the Moon and innovative social networking approaches, is being leveraged to engage a fresh adult audience in lunar science and exploration. In July 2009 the Lunar and Planetary Institute (LPI) launched a lunar education new media portal, MyMoon. LPI is collaborating with lunar scientists, educators, artists - and the public - to populate the site with science content, diverse media exhibits, events, and opportunities for involvement. Through MyMoon, the general public interacts with lunar content that informs them about lunar science research and missions, and engages them in future plans for lunar exploration and eventual habitation. MyMoon’s objectives are to: 1) develop a dynamic, new media learning portal that will enable the general public, with a focus on adults ages 18-35; 2) host a growing, active audience that becomes further involved in NASA’s lunar exploration by sharing their ideas about lunar topics, creating their own materials, and participating in events and experiences; 3) build a community of enthusiasts through social networking media; 4) create a model for online engagement of audiences 18 to 35, and provide detailed evaluation data on best practices and strategies for success. Immersive new media technologies are changing the way that people interact, work, learn, and teach. These provide potentially high-impact opportunities for reaching an audience of young adults, age 18 to 35, that largely is not accessed by, or accessing, NASA (Dittmar, 2004). MyMoon strives to engage - and involve - this audience to build a community of enthusiasts for lunar scientific exploration through social networks and current and emerging new media platforms, including posting videos on YouTube, photo contests on Flickr, and sharing events and challenges on Facebook and Twitter. MyMoon features interactive exhibits that are audience driven and added on a quarterly basis

Distinguished Lectureship Award on the Applications of Physics: Illuminating My Career - From Flash Gordon to Laser Surgery

Science.gov (United States)

Wynne, James

2015-03-01

As a child, I was fascinated by television programs about Flash Gordon. His partner in conquering the universe was Dr. Alexis Zarkov, a physicist, who had invented, among other things, a death ray gun. My personal ``death ray'' was a magnifying glass, focusing sunlight on unsuspecting insects, like crawling ants. I also practiced sneaking up on resting, flying, stinging insects and burning their wings before they could take off and attack me. So I understood something about the power of sunlight. In my senior year of high school, I had a fabulous physics teacher, Lewis E. Love, and I knew after one week that I wanted to be a physicist, not a medical doctor, which is the career my parents wanted me to pursue. It turns out that the first laser functioned on May 16, 1960, just one month before I graduated from high school, and it was inevitable that I would pursue a career working with lasers. My first job as a physicist, during the summer of 1963, was working with lasers at TRG, Inc. a small company whose guru was Gordon Gould, now recognized as the inventor of the laser. After three summers at TRG, I spent three years working on nonlinear optics for my PhD thesis, under the guidance of Prof. Nicolaas Bloembergen, who later won the Nobel Prize in Physics for codifying nonlinear optics. Following completion of my PhD research in 1969, I joined IBM Research, where I have worked ever since. Upon joining the Quantum Electronics group in the Physical Sciences Dept. of the T.J. Watson Research Center, my management told me to ``do something great'' with lasers. After working on atomic spectroscopy with dye lasers through the 1970s, I had the inspiration to acquire an excimer laser for the Laser Physics and Chemistry group. Using this laser, my colleagues and I discovered excimer laser surgery, capable of removing human and animal tissue with great precision, while leaving the underlying and adjacent tissue free of collateral damage. This discovery laid the foundation for

Andrographolide alleviates imiquimod-induced psoriasis in mice via inducing autophagic proteolysis of MyD88.

Science.gov (United States)

Shao, Fenli; Tan, Tao; Tan, Yang; Sun, Yang; Wu, Xingxin; Xu, Qiang

2016-09-01

Psoriasis is a chronic inflammatory skin disease with excessive activation of toll-like receptors (TLRs), which play important roles in developing psoriasis. Targeting TLR signaling remains a challenge for treating psoriasis. Here, we found that andrographolide (Andro), a small-molecule natural product, alleviated imiquimod- but not interleukin 23 (IL-23)-induced psoriasis in mice with reducing expressions of IL-23 and IL-1β in the skin. The improvement in imiquimod-induced psoriasis by Andro was not observed in microtubule-associated protein 1 light chain 3 beta (MAP1LC3B) knockout mice. Furthermore, Andro inhibited mRNA expressions of IL-23, IL-6 and IL-1β but not CD80 and CD86 in bone-marrow derived dendritic cells (BMDCs) treated with lipopolysaccharide (LPS) in a MAP1LC3B-dependent manner. In addition, Andro inhibited imiquimod-induced mRNA expressions of IL-23, IL-6, IL-1β, CD80 and CD86 in BMDCs from mice. Interestingly, Andro induced a degradation of myeloid differentiation factor 88 (MyD88) and blocked the recruitment of TNF receptor-associated factor 6 (TRAF6) to MyD88 upon LPS stimulation in BMDCs from mice. Blockade of autophagic proteolysis using NH4Cl or MAP1LC3B(-/-) BMDCs abolished the Andro-induced MyD88 degradation. In conclusion, Andro controls activation of MyD88-dependent cytokines and alleviates psoriasis in mice via inducing autophagic proteolysis of MyD88, which could be a novel strategy to treat psoriasis. Copyright © 2016 Elsevier Inc. All rights reserved.

Hyaluronan signaling during ozone-induced lung injury requires TLR4, MyD88, and TIRAP.

Directory of Open Access Journals (Sweden)

Zhuowei Li

Full Text Available Ozone exposure is associated with exacerbation of reactive airways disease. We have previously reported that the damage-associated molecular pattern, hyaluronan, is required for the complete biological response to ambient ozone and that hyaluronan fragments signal through toll-like receptor 4 (TLR4. In this study, we further investigated the role of TLR4 adaptors in ozone-induced airway hyperresponsiveness (AHR and the direct response to hyaluronan fragments (HA. Using a murine model of AHR, C57BL/6J, TLR4-/-, MyD88-/-, and TIRAP-/- mice were characterized for AHR after exposure to either ozone (1 ppm × 3 h or HA fragments. Animals were characterized for AHR with methacholine challenge, cellular inflammation, lung injury, and production of pro-inflammatory cytokines. Ozone-exposed C57BL/6J mice developed cellular inflammation, lung injury, pro-inflammatory cytokines, and AHR, while mice deficient in TLR4, MyD88 or TIRAP demonstrated both reduced AHR and reduced levels of pro-inflammatory cytokines including TNFα, IL-1β, MCP-1, IL-6 and KC. The level of hyaluronan was increased after inhalation of ozone in each strain of mice. Direct challenge of mice to hyaluronan resulted in AHR in C57BL/6J mice, but not in TLR4-/-, MyD88-/-, or TIRAP-/- mice. HA-induced cytokine production in wild-type mice was significantly reduced in TLR4-/-, MyD88-/-, or TIRAP-/- mice. In conclusion, our findings support that ozone-induced airway hyperresponsiveness is dependent on the HA-TLR4-MyD88-TIRAP signaling pathway.

41 CFR 301-13.3 - What additional travel expenses may my agency pay under this part?

Science.gov (United States)

2010-07-01

... 13-TRAVEL OF AN EMPLOYEE WITH SPECIAL NEEDS § 301-13.3 What additional travel expenses may my agency... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What additional travel expenses may my agency pay under this part? 301-13.3 Section 301-13.3 Public Contracts and Property...

41 CFR 102-117.285 - What are my choices if a TSP's performance is not satisfactory?

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What are my choices if a TSP's performance is not satisfactory? 102-117.285 Section 102-117.285 Public Contracts and Property... are my choices if a TSP's performance is not satisfactory? You may choose to place a TSP in temporary...

My brief history

CERN Document Server

Hawking, Stephen

2013-01-01

My Brief History recounts Stephen Hawking’s improbable journey, from his postwar London boyhood to his years of international acclaim and celebrity. Lavishly illustrated with rarely seen photographs, this concise, witty, and candid account introduces readers to a Hawking rarely glimpsed in previous books: the inquisitive schoolboy whose classmates nicknamed him Einstein; the jokester who once placed a bet with a colleague over the existence of a particular black hole; and the young husband and father struggling to gain a foothold in the world of physics and cosmology. Writing with characteristic humility and humor, Hawking opens up about the challenges that confronted him following his diagnosis of ALS at age twenty-one. Tracing his development as a thinker, he explains how the prospect of an early death urged him onward through numerous intellectual breakthroughs, and talks about the genesis of his masterpiece A Brief History of Time—one of the iconic books of the twentieth century.

My Folkloristic History of the Việt Nam War: A Non-communist Experience

OpenAIRE

Le, Long S

2015-01-01

Like many families who were on the “wrong” side of the Việt Nam war, my family history has effectively been “displaced” from official discourse in Việt Nam when the country was “reunified” in 1975, as well as in the discourse of public history in the U.S. which has overwhelmingly emphasized the “lessons” of the “American Experience” in Việt Nam. Using my family history as an index of historical processes, I hope to introduce windows on the continuities of what noncommunist Vietnamese do and ...

Systems Engineering Management Procedures

Science.gov (United States)

1966-03-10

hls -iii-rit. -miiiirme 4 --tandnirdized hle iil*ri oa;iu ’ -enperfrm)a- -yýfefi ~lall uitm l--im eniai~ atar n which will lumPremiiieuiea -. v-imli m...with standard component/part selection. and de- tile total system requirements stated in the Sys- tailed functional and physical interfaces: eval- tern...system survivability requirAent. As physical , interface, time, environment, use of these facility requirements are bei developed, standard perts; and

40 CFR 60.2989 - Does this subpart directly affect incineration unit owners and operators in my State?

Science.gov (United States)

2010-07-01

... incineration unit owners and operators in my State? 60.2989 Section 60.2989 Protection of Environment... SOURCES Emission Guidelines and Compliance Times for Other Solid Waste Incineration Units That Commenced... incineration unit owners and operators in my State? (a) No, this subpart does not directly affect incineration...

myBlackBox: Blackbox Mobile Cloud Systems for Personalized Unusual Event Detection

Directory of Open Access Journals (Sweden)

Junho Ahn

2016-05-01

Full Text Available We demonstrate the feasibility of constructing a novel and practical real-world mobile cloud system, called myBlackBox, that efficiently fuses multimodal smartphone sensor data to identify and log unusual personal events in mobile users’ daily lives. The system incorporates a hybrid architectural design that combines unsupervised classification of audio, accelerometer and location data with supervised joint fusion classification to achieve high accuracy, customization, convenience and scalability. We show the feasibility of myBlackBox by implementing and evaluating this end-to-end system that combines Android smartphones with cloud servers, deployed for 15 users over a one-month period.

Flipping my environmental geochemistry classroom using Team-Based Learning

Science.gov (United States)

Griffith, E. M.

2016-02-01

Recent studies indicate that active learning disproportionately benefits STEM students from disadvantaged backgrounds and women in male-dominated fields (Lorenzo et al., 2006; Haak et al., 2011). Freeman et al. (2014) went so far as to suggest that increasing the number of STEM graduates could be done, at least in part, by "abandoning traditional lecturing in favor of active learning". Motivated in part by these previous studies and working at a Hispanic-Serving Institution, I decided to flip my environmental geochemistry course, using Team-Based Learning (TBL) - an instructional strategy for using active learning in small groups (Michaelsen et al., 1982). The course is taught over a 3 hour long class period (once a week) with a mix of upper division undergraduate and graduate students from environmental science, geology, engineering, chemistry, and biological sciences. One of the major learning outcomes of my course is that students "will be able to explain and discuss environmental geochemical data and its significance with their peers." This is practiced each class period throughout the course using TBL, where both undergraduate and graduate students learn from each other and uncover misconceptions. It is essentially one version of a flipped classroom where the students' experience changes from acquiring course content in the classroom to applying course content in the classroom in teams. I will share an overview of the teaching and learning strategy and my experience as well as examples of activities done in the classroom. Cited references: Freeman et al. (2014) PNAS 111: 8410-8415; Haak et al. (2011) Science 332: 1213-1216; Lorenzo et al. (2006) Am J Phys 74: 118-122; Michaelsen et al. (1982) Organ Behav Teaching 7: 13-22.

Wearing my heart on my chest: dating, new relationships, and the reconfiguration of self-esteem after breast cancer.

Science.gov (United States)

Kurowecki, Darya; Fergus, Karen D

2014-01-01

This study investigated women's experiences of establishing an intimate relationship with a new partner after breast cancer diagnosis and treatment. Fifteen breast cancer survivors, who were either actively dating or in a new intimate relationship that began post-diagnosis, participated in semi-structured interviews. Interview transcripts were analyzed using the grounded theory method. The analysis yielded Wearing My Heart on My Chest as the core category with three underlying categories: (1) Losing and Regaining Self and Bodily Esteem; (2) Taking the Leap: Dating and the Obligation to Disclose; and (3) Reclaiming of Self through the New Relationship. The categories refer to the experience of profound vulnerability invoked by the history of breast cancer and the act of verbally and physically revealing this past to a new intimate partner. Disclosure entailed a series of successive 'tests' of the new partner for his ability to accept the physical and psychological ramifications of breast cancer, with the resulting relationship becoming a vehicle through which women regained self-esteem. The process of dating and starting a new intimate relationship had the potential to restore women's self and bodily esteem previously diminished by breast cancer. The reconfiguration of self-esteem following breast cancer is thus experienced as an ongoing process that begins with diagnosis and continues well into the new relationship. Copyright © 2013 John Wiley & Sons, Ltd.

25 CFR 256.16 - Who is responsible for identifying what work will be done on my dwelling?

Science.gov (United States)

2010-04-01

... on my dwelling? 256.16 Section 256.16 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR... my dwelling? The servicing housing office is responsible for identifying what work is to be done on your dwelling or whether your dwelling will be replaced. This includes responsibility to communicate...

Notes on my trip through Nebraska, or some alternative marketing principles for parks and recreation

Science.gov (United States)

Alan R. Graefe

2001-01-01

I started working on this talk on December 19th last year. That was the day I began my trip home from Colorado at the end of my fall semester sabbatical. While traveling through Nebraska I started seeing things that I just couldn't believe. Not just a single thing, but one thing after another. This had to be an omen. I knew immediately that I had found the topic...

41 CFR 301-11.17 - If my agency authorizes per diem reimbursement, will it reduce my M&IE allowance for a meal(s...

Science.gov (United States)

2010-07-01

... for a complimentary meal(s) provided by a hotel/motel? 301-11.17 Section 301-11.17 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false If my agency authorizes...

Differential outcome of infection with attenuated Salmonella in MyD88-deficient mice is dependent on the route of administration.

Science.gov (United States)

Issac, Jincy M; Sarawathiamma, Dhanya; Al-Ketbi, Mai I; Azimullah, Sheikh; Al-Ojali, Samia M; Mohamed, Yassir A; Flavell, Richard A; Fernandez-Cabezudo, Maria J; al-Ramadi, Basel K

2013-01-01

Activation of the innate immune system is a prerequisite for the induction of adaptive immunity to both infectious and non-infectious agents. TLRs are key components of the innate immune recognition system and detect pathogen-associated molecular patterns. Most TLRs utilize the MyD88 adaptor for their signaling pathways. In the current study, we investigated innate and adaptive immune responses to primary as well as secondary Salmonella infections in MyD88-deficient (MyD88(-/-)) mice. Using i.p. or oral route of inoculation, we demonstrate that MyD88(-/-) mice are hypersusceptible to infection by an attenuated, double auxotrophic, mutant of Salmonella enterica serovar Typhimurium (S. typhimurium). This is manifested by 2-3 logs higher bacterial loads in target organs, delayed recruitment of phagocytic cells, and defective production of proinflammatory cytokines in MyD88(-/-) mice. Despite these deficiencies, MyD88(-/-) mice developed Salmonella-specific memory Th1 responses and produced elevated serum levels of anti-Salmonella Abs, not only of Th1-driven (IgG2c, IgG3) but also IgG1 and IgG2b isotypes. Curiously, these adaptive responses were insufficient to afford full protection against a secondary challenge with a virulent strain of S. typhimurium. In comparison with the high degree of mortality seen in MyD88(-/-) mice following i.p. inoculation, oral infections led to the establishment of a state of long-term persistence, characterized by continuous bacterial shedding in animal feces that lasted for more than 6 months, but absence from systemic organs. These findings suggest that the absent expression of MyD88 affects primarily the innate effector arm of the immune system and highlights its critical role in anti-bacterial defense. Copyright © 2012 Elsevier GmbH. All rights reserved.

MySQL based selection of appropriate indexing technique in ...

African Journals Online (AJOL)

This paper deals with selection of appropriate indexing technique applied on MySQL Database for a health care system and related performance issues using multiclass support vector machine (SVM). The patient database is generally huge and contains lot of variations. For the quick search or fast retrieval of the desired ...

40 CFR 63.2164 - If I monitor brew ethanol, what are my monitoring installation, operation, and maintenance...

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 12 2010-07-01 2010-07-01 true If I monitor brew ethanol, what are my... monitor brew ethanol, what are my monitoring installation, operation, and maintenance requirements? (a... considered by us to be generally optimum. Use the brew-to-exhaust correlation equation established under § 63...

45 CFR 2520.60 - What government-wide requirements apply to staff fundraising under my AmeriCorps grant?

Science.gov (United States)

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false What government-wide requirements apply to staff fundraising under my AmeriCorps grant? 2520.60 Section 2520.60 Public Welfare Regulations Relating to Public... C PROGRAMS § 2520.60 What government-wide requirements apply to staff fundraising under my Ameri...

Educating My Replacement

Science.gov (United States)

Tarter, Jill

The search for extraterrestrial intelligence (SETI) could succeed tomorrow, decades from now, or never. The nature of this scientific exploration is such that we cannot predict success on any timescale; we only know that if we do not search, we cannot succeed. Having spent my scientific career in this field, I know perhaps better than anyone that the researchers of tomorrow may hold the key. Thus I have an enormous and vested interest in trying to educate the next generation of scientists. Because SETI excites such enthusiasm in young and old alike, I have an excellent opportunity to capture hearts and minds and leverage this interest into science education at many levels. Astrobiology is the new banner for inter- and cross-disciplinary investigations aimed at answering the big question "Are we alone?" The story of cosmic evolution is one that scientists at the SETI Institute have been telling for decades. We have used it as the framework for developing supplementary materials for elementary and middle schools called Life In The Universe. Currently we are tackling a year-long curriculum called Voyages Through Time for ninth grade students. This curriculum is delivered on CD-ROM and supported by the web. It focuses on evolution as a theme and stresses the contributions made from all the traditionally isolated branches of science --- and by the way, it's fun! I am a product of the post-Sputnik era and the American emphasis on science and engineering education. In the New York City bedroom community where I grew up, every school bond issue passed at every election. So I am appalled at the difficulties, the impecuniousness, and bureaucratic nonsense our pilot and field test teachers encounter on a daily basis. I am also overjoyed that even under such unreasonable conditions, I meet enthusiastic teachers who care about their students and are dedicated to helping them achieve the best possible education. Not all students will become scientists, nor should they. However

Regulator of calcineurin 1 differentially regulates TLR-dependent MyD88 and TRIF signaling pathways.

Directory of Open Access Journals (Sweden)

Zheng Pang

Full Text Available Toll-like receptors (TLRs recognize the conserved molecular patterns in microorganisms and trigger myeloid differentiation primary response 88 (MyD88 and/or TIR-domain-containing adapter-inducing interferon-β (TRIF pathways that are critical for host defense against microbial infection. However, the molecular mechanisms that govern TLR signaling remain incompletely understood. Regulator of calcineurin-1 (RCAN1, a small evolutionarily conserved protein that inhibits calcineurin phosphatase activity, suppresses inflammation during Pseudomonas aeruginosa infection. Here, we define the roles for RCAN1 in P. aeruginosa lipopolysaccharide (LPS-activated TLR4 signaling. We compared the effects of P. aeruginosa LPS challenge on bone marrow-derived macrophages from both wild-type and RCAN1-deficient mice and found that RCAN1 deficiency increased the MyD88-NF-κB-mediated cytokine production (IL-6, TNF and MIP-2, whereas TRIF-interferon-stimulated response elements (ISRE-mediated cytokine production (IFNβ, RANTES and IP-10 was suppressed. RCAN1 deficiency caused increased IκBα phosphorylation and NF-κB activity in the MyD88-dependent pathway, but impaired ISRE activation and reduced IRF7 expression in the TRIF-dependent pathway. Complementary studies of a mouse model of P. aeruginosa LPS-induced acute pneumonia confirmed that RCAN1-deficient mice displayed greatly enhanced NF-κB activity and MyD88-NF-κB-mediated cytokine production, which correlated with enhanced pulmonary infiltration of neutrophils. By contrast, RCAN1 deficiency had little effect on the TRIF pathway in vivo. These findings demonstrate a novel regulatory role of RCAN1 in TLR signaling, which differentially regulates MyD88 and TRIF pathways.

My Scientific Journey: From an Agrarian Start to an Academic Setting.

Science.gov (United States)

Bahr, Janice M

2017-02-08

This article is a combination of an autobiography and a review of outstanding research done by over 70 graduate students, postdoctoral fellows, and visiting scientists along with excellent collaborators during my over-40-year career as a professor of reproductive physiology at the University of Illinois, Urbana-Champaign. I have also shared thoughts on mentoring, how research has changed over the years, and the future of reproductive physiology. I provide the reader with a snapshot of the challenges faced by a woman eager to obtain a PhD under the guidance of renowned professors in the early 1970s and to be hired as the first woman, and the only permanent female faculty member, for more than 20 years on a faculty of 40 men. As a comparative reproductive physiologist, I describe the various animal models used because they were the best models to answer specific questions in reproduction. Also, my graduate students and postdoctoral fellows were given the freedom to identify their research topics, articulate hypotheses to be tested, and select appropriate animal models. This approach caused students to take ownership of their research, resulting in the development of independent and creative scientists and over 170 publications, excluding chapters in top-tier journals. Finally, I am so grateful for a truly rich life mentoring graduate students and postdoctoral fellows who have become my lifelong friends.

31 CFR 370.40 - Can I be held accountable if my negligence contributes to a forged signature?

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Can I be held accountable if my negligence contributes to a forged signature? 370.40 Section 370.40 Money and Finance: Treasury Regulations... if my negligence contributes to a forged signature? (a) General. If your failure to exercise ordinary...

40 CFR 122.31 - As a Tribe, what is my role under the NPDES storm water program?

Science.gov (United States)

2010-07-01

... ELIMINATION SYSTEM Permit Application and Special NPDES Program Requirements § 122.31 As a Tribe, what is my... 40 Protection of Environment 21 2010-07-01 2010-07-01 false As a Tribe, what is my role under the NPDES storm water program? 122.31 Section 122.31 Protection of Environment ENVIRONMENTAL PROTECTION...

A Web-based Examination System Based on PHP+MySQL.

Science.gov (United States)

Wen, Ji; Zhang, Yang; Yan, Yong; Xia, Shunren

2005-01-01

The design and implementation of web-based examination system constructed by PHP and MySQL is presented in this paper. Three primary parts, including students',teachers' and administrators', are introduced and analyzed in detail. Initial application has demonstrated the system's feasibility and reasonability.*

Relating genes to function: identifying enriched transcription factors using the ENCODE ChIP-Seq significance tool.

Science.gov (United States)

Auerbach, Raymond K; Chen, Bin; Butte, Atul J

2013-08-01

Biological analysis has shifted from identifying genes and transcripts to mapping these genes and transcripts to biological functions. The ENCODE Project has generated hundreds of ChIP-Seq experiments spanning multiple transcription factors and cell lines for public use, but tools for a biomedical scientist to analyze these data are either non-existent or tailored to narrow biological questions. We present the ENCODE ChIP-Seq Significance Tool, a flexible web application leveraging public ENCODE data to identify enriched transcription factors in a gene or transcript list for comparative analyses. The ENCODE ChIP-Seq Significance Tool is written in JavaScript on the client side and has been tested on Google Chrome, Apple Safari and Mozilla Firefox browsers. Server-side scripts are written in PHP and leverage R and a MySQL database. The tool is available at http://encodeqt.stanford.edu. abutte@stanford.edu Supplementary material is available at Bioinformatics online.

Examples as Method? My Attempts to Understand Assessment and Fairness (in the Spirit of the Later Wittgenstein)

Science.gov (United States)

Davis, Andrew

2009-01-01

What is "fairness" in the context of educational assessment? I apply this question to a number of contemporary educational assessment practices and policies. My approach to philosophy of education owes much to Wittgenstein. A commentary set apart from the main body of the paper focuses on my style of philosophising. Wittgenstein teaches us to…

My Career as a Teacher and a Political Scientist: If I Knew Then What I Know Now

Science.gov (United States)

Richards, Erin

2018-01-01

This article addresses my professional development as a teacher and political scientist throughout the span of a 15-year career in political science. Also included are reflections on graduate education and the compatibility and necessary dual focus on both political science and teaching in the academy today as it relates to my present-day…

In Vivo Role of TLR2 and MyD88 Signaling in Eliciting Innate Immune Responses in Staphylococcal Endophthalmitis

Science.gov (United States)

Talreja, Deepa; Singh, Pawan Kumar; Kumar, Ashok

2015-01-01

Purpose. The purpose of this study was to investigate the protective mechanisms evoked by TLR2 and MyD88 signaling in bacterial endophthalmitis in vivo. Methods. Endophthalmitis was induced in wild-type (WT), TLR2−/−, MyD88−/−, and Cnlp−/− mice by intravitreal injections of a laboratory strain (RN6390) and two endophthalmitis isolates of Staphylococcus aureus. Disease progression was monitored by assessing corneal and vitreous haze, bacterial burden, and retinal tissue damage. Levels of inflammatory cytokines/chemokines were determined using quantitative RT-PCR (qRT-PCR) and ELISA. Flow cytometry was used to assess neutrophil infiltration. Cathelicidin-related antimicrobial peptide (CRAMP) expression was determined by immunostaining and dot blot. Results. Eyes infected with either laboratory or clinical isolates exhibited higher levels of inflammatory mediators at the early stages of infection (≤24 hours) in WT mice than in TLR2−/− or MyD88−/− mice. However, their levels surpassed that of WT mice at the later stages of infection (>48 hours), coinciding with increased bacterial burden and retinal damage. Both TLR2−/− and MyD88−/− retinas produced reduced levels of CRAMP, and its deficiency (Cnlp−/−) rendered the mice susceptible to increased bacterial burden and retinal tissue damage as early as 1 day post infection. Analyses of inflammatory mediators and neutrophil levels in WT versus Cnlp−/− mice showed a trend similar to that observed in TLR2 and MyD88 KO mice. Furthermore, we observed that even a 10-fold lower infective dose of S. aureus was sufficient to cause endophthalmitis in TLR2−/− and MyD88−/− mice. Conclusions. TLR2 and MyD88 signaling plays an important role in protecting the retina from staphylococcal endophthalmitis by production of the antimicrobial peptide CRAMP. PMID:25678692

MyReDiary: Co-Designing for Collaborative Articulation in Physical Rehabilitation

DEFF Research Database (Denmark)

Bagalkot, Naveen L.; Sokoler, Tomas

2011-01-01

In this paper we present our exploration of co-designing for supporting a collaborative articulation of rehabilitation process. Based on our reading of key CSCW literature, we describe three facets of a collaboratively articulated rehab process: Interdependence, Distributed Process, and Interoper......In this paper we present our exploration of co-designing for supporting a collaborative articulation of rehabilitation process. Based on our reading of key CSCW literature, we describe three facets of a collaboratively articulated rehab process: Interdependence, Distributed Process......, and Interoperability. We highlight Magic-Mirror- Spiral, the design ideal guiding the co-designing of MyReDiary that is aimed to support the three facets as an example in this regard. We offer the conceptual understanding of Collaborative Articulation, the Magic-Mirror-Spiral and MyReDiary as a ‘compositional Whole...

PENGEMBANGAN EVALUASI PEMBELAJARAN BERBASIS MULTIMEDIA DENGAN FLASH, PHP, DAN MySQL

Directory of Open Access Journals (Sweden)

Hadi Sutopo

2012-01-01

Full Text Available Computer-Based Testing (CBT program was launched for years to give test takers the options of taking computerized version of test. The application which generates academic score is developed as a server-side with Adobe Flash. Flash is well known as a powerful and dynamic front-end for the Web. However, Flash is also great interface for server-side applications. PHP can launch server-side script using Flash as a front-end and pass variables back and forth between Flash and the PHP pages. Along with PHP, MySQL can be used to store data and later retrieve it. Using Flash as a front-end, data and variables are passed between the MySQL database, PHP, and Flash to enhance application's functionality in managing databases.

43 CFR 429.37 - Does interest accrue on monies owed to the United States during my appeal process?

Science.gov (United States)

2010-10-01

... United States during my appeal process? 429.37 Section 429.37 Public Lands: Interior Regulations Relating... States during my appeal process? Except for any period in the appeal process during which a stay is then... decision to OHA, or during judicial review of final agency action. ...

40 CFR 63.1591 - What are my notification requirements?

Science.gov (United States)

2010-07-01

... Requirements § 63.1591 What are my notification requirements? (a) If you have an industrial POTW treatment plant or a new or reconstructed non-industrial POTW which is a major source of HAP, and your State has... date; and (4) A brief description of the nature, size, design, and method of operation of your POTW...

iDESWEB: Práctica 9: PHP 3 (MySQL y acceso a una base de datos)

OpenAIRE

Luján Mora, Sergio

2012-01-01

Aprender a administrar una base de datos con MySQL. Conocer algunas herramientas que ayudan a administrar una base de datos de MySQL. Aprender a acceder a una base de datos desde PHP. Aprender a realizar una consulta SELECT y mostrar el resultado en una página web. Sitio web del curso: http://idesweb.es/

DMPD: MyDths and un-TOLLed truths: sensor, instructive and effector immunity totuberculosis. [Dynamic Macrophage Pathway CSML Database

Lifescience Database Archive (English)

Full Text Available 18191460 MyDths and un-TOLLed truths: sensor, instructive and effector immunity totuberculosis...g) (.svg) (.html) (.csml) Show MyDths and un-TOLLed truths: sensor, instructive and effector immunity totuberculosis...e and effector immunity totuberculosis. Authors Reiling N, Ehlers S, Holscher C. Publication Immunol Lett. 2

45 CFR 2540.670 - Will my qualification to participate or eligibility for benefits be suspended during the review...

Science.gov (United States)

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false Will my qualification to participate or eligibility for benefits be suspended during the review process? 2540.670 Section 2540.670 Public Welfare... ADMINISTRATIVE PROVISIONS False or Misleading Statements § 2540.670 Will my qualification to participate or...

Embracing "All But My Life" by Gerda Weissmann Klein.

Science.gov (United States)

Foster, Harold M.

1997-01-01

Discusses Gerda Weissmann Klein's book, "All But My Life," which chronicles the author's journey from a normal young (Jewish) woman to a slave in Nazi labor camps for six years. Argues that the book is well written, has characters of depth and complexity, affirms life through the ordeal of the Holocaust, and is a popular book with…

My drama : story-based game for understanding emotions in context

NARCIS (Netherlands)

Shen, X.; Barakova, E.I.; Poppe, R.; Meyer, J.J.; Veltkamp, R.; Dastani, M.

2017-01-01

This paper presents My Drama, a story-based game application that helps to understand emotions in context. The game was developed for young people with autism, who usually have trouble understanding the non-verbal expression of emotions. We combined elements of drama therapy and mobile game design

Secularism, post-structuralism or beyond? A response to my critics

NARCIS (Netherlands)

Bader, V.

2008-01-01

All three critics raise important issues but also show that thecomplexity of my approach is prone to many misunderstandings. Apartfrom responding to the critical charges, this piece also serves toexplain to the readers why I did things as I did in order toprevent some of these misunderstandings.

From my Home: Dvarionas: Elegie; Pärt: Fratres / Patric Wiklacz

Index Scriptorium Estoniae

Wiklacz, Patric

1997-01-01

Uuest heliplaadist "From my Home: Dvarionas: Elegie; Pärt: Fratres; Barkauskas: Partita; Vasks: Musica Dolorosa; Pelecis: Concerto for Violin, Piano and String Orchestra, "Neverthless"; Plakidis: Two Grasshopper Dances; Tüür: Conversio. Deutsche Kammerphilharmonie, Gidon Kremer (violon), Vadim Sacharov (piano)" Teldec 0630-14654-2 (79 minutes:DDD)

5 CFR 892.301 - How do I pay my premium?

Science.gov (United States)

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false How do I pay my premium? 892.301 Section 892.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL FLEXIBLE BENEFITS PLAN: PRE-TAX PAYMENT OF HEALTH BENEFITS PREMIUMS Contributions and...

MedlinePlus FAQ: Will MedlinePlus work on my mobile device?

Science.gov (United States)

... mobile.html Question: Will MedlinePlus work on my mobile device? To use the sharing features on this page, ... Some video content might not play on your mobile device. See our FAQ on playing videos on phones ...

My Skin – a self-questionnaire for assessment of the emotional-cognitive representation of skin

Directory of Open Access Journals (Sweden)

Marlena M. Kossakowska

2016-02-01

Full Text Available Background The aims of this paper are: 1 to present the My Skin questionnaire, 2 to report the preliminary results of a study on the emotional-cognitive skin representation, and 3 to encourage dermatologists and other specialists to use the My Skin questionnaire in their research. The inspiration for a new tool measuring the emotional and cognitive representation of skin was the psychological conception of the ‘skin ego’. Participants and procedure My Skin, a self-questionnaire (MSQ, was used to measure the emotional and cognitive representation of an individual’s skin. It consists of two main scales: satisfaction with the skin condition (AB and awareness of the biopsychosocial functions of the skin (C. The Body Esteem Scale, Body Self Questionnaire and Self-Esteem Scale were used to validate the MSQ. The participants were: healthy individuals (n = 343 and dermatology patients (psoriasis, vitiligo, juvenile acne, n = 84. Results The psychometric parameters are presented in this article. The internal consistency reliabilities for subscales are in the range of .75 and .95. This article also presents preliminary basic statistics for the skin representation of dermatology patients and healthy people. Conclusions My Skin questionnaire is a valid tool for assessing cognitive and emotional representation of skin and may be used in psychodermatology and esthetic dermatology to assess satisfaction with and awareness of skin.

Scientific Outreach for K-6 Students: The LTER Schoolyard Children's Book Series

Science.gov (United States)

Williams, M.; McKnight, D.

2009-04-01

, written by Antarctic scientist Diane McKnight, describes the first documented encounter with a live seal in the remote McMurdo Dry Valleys of Antarctica. Additional website information on the children's book "My Water Comes from the Mountains" is available at http://intranet.lternet.edu/archives/documents/Newsletters/NetworkNews/fall04/fall04_pg15.htm. All 433 pieces of orginal artwork for My Water Comes from the Mountains can be viewed at http://culter.colorado.edu/exec/Mywater/mywater_search_page.cgi.

30 CFR 285.615 - What other reports or notices must I submit to MMS under my approved SAP?

Science.gov (United States)

2010-07-01

... MMS under my approved SAP? 285.615 Section 285.615 Mineral Resources MINERALS MANAGEMENT SERVICE... CONTINENTAL SHELF Plans and Information Requirements Activities Under An Approved Sap § 285.615 What other reports or notices must I submit to MMS under my approved SAP? (a) You must notify MMS in writing within...

American Self-Fashioning in Helen Foster Snow's My China Years.

Directory of Open Access Journals (Sweden)

Constance J. Post

2013-11-01

Full Text Available In My China Years: A Memoir, Helen Foster Snow draws upon her Puritan roots in fashioning an American self that affirms the power of an individual exemplary life, the ability to exercise free will amid struggle, an optimism borne of hope, and a way to represent failure and success. Self-fashioning, which Stephen Greenblatt attributes to the rise of an autonomous self in early modern Europe, is shaped by Snow as a distinctly American identity based on a secular Puritanism she found more congenial than the Puritanism of her ancestors on both sides of the Atlantic. The many resemblances noted by Snow between the Chinese Communist Army and seventeenth-century English Puritanism led her to interrogate Puritanism, both in its traditional form and its secularised variant. What emerges in the pages of My China Years is an attempt to fashion an American self by negotiating an old Puritanism with the new by way of a triangulation with China.

Embodiment and Desire: All About My Mother and Gender in The Margin

Directory of Open Access Journals (Sweden)

Sônia Weidner Maluf

2002-01-01

Full Text Available This essays does a reading of Pedro Almodovar’s film All About My Mother, focusing on the transvestite character, Agrado. After drawing a comparison with other films on the subject of transgendering, I discuss notions of embodiedness and the construction of the subject by placing them in the context of theories about the body in Brazilian ethnology. My purpose is to offer some elements for a reflection on the experiences at/of the margins as a way of renewing the theoretical debates in feminist and gender studies. The bodily experience of ‘becoming the other’ dramatizes the mechanisms that are in play in the construction of difference and can be seen as an anti-hierarchical force destabilizing dominant politics of subjectivity.

How EXCELERATOR changed my job

Energy Technology Data Exchange (ETDEWEB)

Weir, D.

1988-01-01

I started using a Computer-Aided Software Engineering (CASE) analysis/design tool two years ago in the Administrative Data Processing Division (ADP) and have observed that the way I approach my job has changed. The end product is the same, but the product is derived differently. The ability to change what is done gives freedom to experiment and iterate. This freedom has changed some steps and resequenced others in arriving at a structured specification for a new system. Additionally, the analysis capability of the tools allow the performance of work that was often disregarded because it was either too tedious or overwhelming. This presentation will address the changes observed in the process of analysis and design using CASE. 2 figs.

30 CFR 250.414 - What must my drilling prognosis include?

Science.gov (United States)

2010-07-01

...) Projected plans for logging; (c) Planned safe drilling margin between proposed drilling fluid weights and... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must my drilling prognosis include? 250... OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Drilling Operations...

A Brilliant Example for Women--Comments on "My Brilliant Career"

Science.gov (United States)

Zhang, Xiuqing

2014-01-01

Based on the theory of American feminist critic Elaine Showalter, this paper analyzes a peculiar feature of early Australian novel "My Brilliant Career" and discovers that it spans three phases of Women's Literature. Through her indefatigable strive for equality between men and women, independent personality and self-fulfillment, the…

You want to do what? My mother's choice to have direct-to-consumer genetic testing.

Science.gov (United States)

Varga, Elizabeth A

2012-06-01

As a genetic counselor, I had mixed opinions when my mother told me of her intent to undergo genomewide, SNP-based direct-to-consumer (DTC) genetic testing. I cautioned her that results could be misleading, could increase anxiety and were often of limited clinical validity or utility. I warned of the possibility of learning unintended health information and expressed concerns about how the information might be used by a private company. I told her about the variability in results among companies. Yet, she persisted in her desire, reminding me that she was an informed consumer. After reviewing her goals and understanding of the information she might receive, she elected to proceed. Despite my insistence that I would not be her personal genetic counselor, when the results came back, I found myself immersed in her genetic data. In this manuscript, I will examine how this personal experience challenged my perceptions of DTC testing.

The Affordability of MyPlate: An Analysis of SNAP Benefits and the Actual Cost of Eating According to the Dietary Guidelines.

Science.gov (United States)

Mulik, Kranti; Haynes-Maslow, Lindsey

2017-09-01

To estimate the funds required to support a MyPlate diet and to estimate the additional costs needed for Supplemental Nutrition Assistance Program recipients to adhere to the MyPlate diet. Using the US Department of Agriculture's (USDA's) MyPlate dietary guidelines that specify recommendations for individuals based on age and gender and retail price data from the USDA, the cost of following USDA's MyPlate guidelines for consuming 3 meals daily was estimated for the following individuals: children, adolescents, female adults, male adults, female seniors, male seniors, and a 4-person family. Cost of consuming a MyPlate diet, including canned, frozen, and fresh produce as part of the diet. Descriptive analysis of the cost of consuming a MyPlate diet. Consuming a MyPlate diet consisting of only fresh fruits and vegetables is the most expensive diet. The monthly additional costs on an individual basis is the largest for boys aged 12-17 years ($75/mo) because they have the largest quantity of food consumed compared with all other gender and age groups. The monthly cost for a family of 4 ranged from $1,109 to $1,249/mo. The monetary amount of Supplemental Nutrition Assistance Program benefits may be insufficient to support a healthy diet recommended by federal nutrition guidelines. Copyright © 2017 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

Lack of MyD88 protects the immunodeficient host against fatal lung inflammation triggered by the opportunistic bacteria Burkholderia cenocepacia.

Science.gov (United States)

Ventura, Grasiella M de C; Balloy, Viviane; Ramphal, Reuben; Khun, Huot; Huerre, Michel; Ryffel, Bernhard; Plotkowski, Maria-Cristina M; Chignard, Michel; Si-Tahar, Mustapha

2009-07-01

Burkholderia cenocepacia is an opportunistic pathogen of major concern for cystic fibrosis patients as well as immunocompromised cancer patients and transplant recipients. The mechanisms by which B. cenocepacia triggers a rapid health deterioration of the susceptible host have yet to be characterized. TLR and their key signaling intermediate MyD88 play a central role in the detection of microbial molecular patterns and in the initiation of an effective immune response. We performed a study to better understand the role of TLR-MyD88 signaling in B. cenocepacia-induced pathogenesis in the immunocompromised host, using an experimental murine model. The time-course of several dynamic parameters, including animal survival, bacterial load, and secretion of critical inflammatory mediators, was compared in infected and immunosuppressed wild-type and MyD88(-/-) mice. Notably, when compared with wild-type mice, infected MyD88(-/-) animals displayed significantly reduced levels of inflammatory mediators (including KC, TNF-alpha, IL-6, MIP-2, and G-CSF) in blood and lung airspaces. Moreover, despite a higher transient bacterial load in the lungs, immunosuppressed mice deficient in MyD88 had an unexpected survival advantage. Finally, we showed that this B. cenocepacia-induced life-threatening infection of wild-type mice involved the proinflammatory cytokine TNF-alpha and could be prevented by corticosteroids. Altogether, our findings demonstrate that a MyD88-dependent pathway can critically contribute to a detrimental host inflammatory response that leads to fatal pneumonia.

How can I improve my students' ability in doing laboratory practical ...

African Journals Online (AJOL)

From my experience of teaching in KCTE and class N23 (Natural science ... active in class participation and did what was given to them in theoretical approach. ... That was why I chose them specially in doing Practical Analytical Chemistry-I ...

30 CFR 250.181 - When may the Secretary cancel my lease and when am I compensated for cancellation?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When may the Secretary cancel my lease and when... may the Secretary cancel my lease and when am I compensated for cancellation? If the Secretary cancels.... Section 250.185 states conditions under which you will receive no compensation. The Secretary may cancel a...

"Who I'd Like to Meet: Lil Wayne and God" Self-Disclosure in Emerging Adults' MySpace Profiles

Science.gov (United States)

Bobkowski, Piotr Szymon

2010-01-01

Self-disclosure--the communication of information about oneself to another--is fundamental to the construction of a personal online presence. In many online venues (e.g., MySpace, Facebook) users self-disclose themselves into being. This study examined who said what about themselves on MySpace and how consistently they did so in comparison to…

40 CFR 63.7927 - What are my inspection and monitoring requirements for closed vent systems and control devices?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 13 2010-07-01 2010-07-01 false What are my inspection and monitoring... Pollutants: Site Remediation Closed Vent Systems and Control Devices § 63.7927 What are my inspection and... temperature at the inlet of the catalyst bed, the hourly average temperature at the outlet of the catalyst bed...

43 CFR 2.87 - How will the Department process my Touhy Request?

Science.gov (United States)

2010-10-01

... TESTIMONY; FREEDOM OF INFORMATION ACT Legal Process: Testimony by Employees and Production of Records Responsibility of the Department § 2.87 How will the Department process my Touhy Request? (a) The appropriate...

Inflammation- and tumor-induced anorexia and weight loss require MyD88 in hematopoietic/myeloid cells but not in brain endothelial or neural cells.

Science.gov (United States)

Ruud, Johan; Wilhelms, Daniel Björk; Nilsson, Anna; Eskilsson, Anna; Tang, Yan-Juan; Ströhle, Peter; Caesar, Robert; Schwaninger, Markus; Wunderlich, Thomas; Bäckhed, Fredrik; Engblom, David; Blomqvist, Anders

2013-05-01

Loss of appetite is a hallmark of inflammatory diseases. The underlying mechanisms remain undefined, but it is known that myeloid differentiation primary response gene 88 (MyD88), an adaptor protein critical for Toll-like and IL-1 receptor family signaling, is involved. Here we addressed the question of determining in which cells the MyD88 signaling that results in anorexia development occurs by using chimeric mice and animals with cell-specific deletions. We found that MyD88-knockout mice, which are resistant to bacterial lipopolysaccharide (LPS)-induced anorexia, displayed anorexia when transplanted with wild-type bone marrow cells. Furthermore, mice with a targeted deletion of MyD88 in hematopoietic or myeloid cells were largely protected against LPS-induced anorexia and displayed attenuated weight loss, whereas mice with MyD88 deletion in hepatocytes or in neural cells or the cerebrovascular endothelium developed anorexia and weight loss of similar magnitude as wild-type mice. Furthermore, in a model for cancer-induced anorexia-cachexia, deletion of MyD88 in hematopoietic cells attenuated the anorexia and protected against body weight loss. These findings demonstrate that MyD88-dependent signaling within the brain is not required for eliciting inflammation-induced anorexia. Instead, we identify MyD88 signaling in hematopoietic/myeloid cells as a critical component for acute inflammatory-driven anorexia, as well as for chronic anorexia and weight loss associated with malignant disease.

About the Translation of the Poem by Gabriel Aresti “The House of my Father”

Directory of Open Access Journals (Sweden)

Luarsabishvili, Vladimer

2010-01-01

Full Text Available In this article, several versions of the poem “My father’s house” by Gabriel Aresti are analysed. The author studies in depth the theory and the practice of translation with the example of several translators. In the article, several specific examples of diverse translations by K. Gamsakhurdia, M. Tsvetaeva, V. Nabokov, J. Borges, etc, are quoted. At the end of his work, the author suggests his own version of the russian translation of the poem by Gabriel Aresti “My father’s house”.

Inquiry into Teaching: Using Reflective Teaching to Improve My Practice

Science.gov (United States)

Pennington, Sarah E.

2015-01-01

How effective is reflective teaching in increasing the engagement and achievement of pre-service teachers when utilized by a first-year college instructor? This article documents a practitioner inquiry project in which I reflected both on my own observations and student feedback regarding what teaching methods were most beneficial in an…

Wandering accelerators throughout my life (1)

International Nuclear Information System (INIS)

Nakai, Kozi

2009-01-01

My wanderings about accelerators started being stimulated by nuclear physics activities of the Kikuchi Laboratory in Osaka University. When the university was founded in 1931, President Nagaoka put emphasis on the nuclear physics programs and called Professor Kikuchi to establish a center of nuclear physics. Since then the laboratory successfully cultivated the new field through studies of the neutron-nucleus interactions with a Cockcroft-Walton accelerator, the beta-decay study with a Cyclotron before the World-War II. Those accelerators were all home made, including the second cyclotron built after the war. Through such experimental programs, the Kikuchi Laboratory brought up many talented physicists in accelerator and nuclear science. (author)

Stories fort/da my significant other

Directory of Open Access Journals (Sweden)

Claire Farago

2016-12-01

Full Text Available My statement is abstract enough. I tried to give a sense of our interactions as they fluidly move between the personal and the professional. Difficult to write about the personal in a professional venue. We are all aware of these distinctions – that is not the problem – but we are also aware that the boundaries between personal and professional remain fuzzy. I wanted to give readers of JoAH a sense of our communicating practices – of the unsayable hanging within the said. Not easy to render and I don’t think I did a very good job, but you can judge for yourselves.

30 CFR 285.659 - What requirements must I include in my SAP, COP, or GAP regarding air quality?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What requirements must I include in my SAP, COP, or GAP regarding air quality? 285.659 Section 285.659 Mineral Resources MINERALS MANAGEMENT SERVICE... must I include in my SAP, COP, or GAP regarding air quality? (a) You must comply with the Clean Air Act...

30 CFR 250.116 - How do I determine producibility if my well is in the Gulf of Mexico?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I determine producibility if my well is in the Gulf of Mexico? 250.116 Section 250.116 Mineral Resources MINERALS MANAGEMENT SERVICE... Performance Standards § 250.116 How do I determine producibility if my well is in the Gulf of Mexico? If your...

41 CFR 102-193.25 - What type of records management business process improvements should my agency strive to achieve?

Science.gov (United States)

2010-07-01

... management business process improvements should my agency strive to achieve? 102-193.25 Section 102-193.25...-193.25 What type of records management business process improvements should my agency strive to... correspondence; (b) Design forms that are easy to fill-in, read, transmit, process, and retrieve, and reduce...

41 CFR 301-50.5 - What is my liability if I do not use my agency's TMS or the E-Gov Travel Service, and an...

Science.gov (United States)

2010-07-01

...? 301-50.5 Section 301-50.5 Public Contracts and Property Management Federal Travel Regulation System... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What is my liability if... penalties, or other additional costs (e.g., higher airfares, rental car charges, or hotel rates). In...

30 CFR 285.907 - How will MMS process my decommissioning application?

Science.gov (United States)

2010-07-01

... application? 285.907 Section 285.907 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Decommissioning Decommissioning Applications § 285.907 How will MMS process my decommissioning application? (a...

30 CFR 285.905 - When must I submit my decommissioning application?

Science.gov (United States)

2010-07-01

... application? 285.905 Section 285.905 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Decommissioning Decommissioning Applications § 285.905 When must I submit my decommissioning application? You must...

Cold exposure increases slow-type myosin heavy chain 1 (MyHC1) composition of soleus muscle in rats.

Science.gov (United States)

Mizunoya, Wataru; Iwamoto, Yohei; Sato, Yusuke; Tatsumi, Ryuichi; Ikeuchi, Yoshihide

2014-03-01

The aim of this study was to examine the effects of cold exposure on rat skeletal muscle fiber type, according to myosin heavy chain (MyHC) isoform and metabolism-related factors. Male Wistar rats (7 weeks old) were housed individually at 4 ± 2°C as a cold-exposed group or at room temperature (22 ± 2°C) as a control group for 4 weeks. We found that cold exposure significantly increased the slow-type MyHC1 content in the soleus muscle (a typical slow-type fiber), while the intermediate-type MyHC2A content was significantly decreased. In contrast to soleus, MyHC composition of extensor digitorum longus (EDL, a typical fast-type fiber) and gastrocnemius (a mix of slow-type and fast-type fibers) muscle did not change from cold exposure. Cold exposure increased mRNA expression of mitochondrial uncoupling protein 3 (UCP3) in both the soleus and EDL. Cold exposure also increased mRNA expression of myoglobin, peroxisome proliferator-activated receptor gamma coactivator 1α (PGC1α) and forkhead box O1 (FOXO1) in the soleus. Upregulation of UCP3 and PGC1α proteins were observed with Western blotting in the gastrocnemius. Thus, cold exposure increased metabolism-related factors in all muscle types that were tested, but MyHC isoforms changed only in the soleus. © 2013 Japanese Society of Animal Science.

Experience with ATLAS MySQL PanDA database service

International Nuclear Information System (INIS)

Smirnov, Y; Wlodek, T; Hover, J; Smith, J; Wenaus, T; Yu, D; De, K; Ozturk, N

2010-01-01

The PanDA distributed production and analysis system has been in production use for ATLAS data processing and analysis since late 2005 in the US, and globally throughout ATLAS since early 2008. Its core architecture is based on a set of stateless web services served by Apache and backed by a suite of MySQL databases that are the repository for all PanDA information: active and archival job queues, dataset and file catalogs, site configuration information, monitoring information, system control parameters, and so on. This database system is one of the most critical components of PanDA, and has successfully delivered the functional and scaling performance required by PanDA, currently operating at a scale of half a million jobs per week, with much growth still to come. In this paper we describe the design and implementation of the PanDA database system, its architecture of MySQL servers deployed at BNL and CERN, backup strategy and monitoring tools. The system has been developed, thoroughly tested, and brought to production to provide highly reliable, scalable, flexible and available database services for ATLAS Monte Carlo production, reconstruction and physics analysis.

Experience with ATLAS MySQL PanDA database service

Energy Technology Data Exchange (ETDEWEB)

Smirnov, Y; Wlodek, T; Hover, J; Smith, J; Wenaus, T; Yu, D [Physics Department, Brookhaven National Laboratory, Upton, NY 11973-5000 (United States); De, K; Ozturk, N [Department of Physics, University of Texas at Arlington, Arlington, TX, 76019 (United States)

2010-04-01

The PanDA distributed production and analysis system has been in production use for ATLAS data processing and analysis since late 2005 in the US, and globally throughout ATLAS since early 2008. Its core architecture is based on a set of stateless web services served by Apache and backed by a suite of MySQL databases that are the repository for all PanDA information: active and archival job queues, dataset and file catalogs, site configuration information, monitoring information, system control parameters, and so on. This database system is one of the most critical components of PanDA, and has successfully delivered the functional and scaling performance required by PanDA, currently operating at a scale of half a million jobs per week, with much growth still to come. In this paper we describe the design and implementation of the PanDA database system, its architecture of MySQL servers deployed at BNL and CERN, backup strategy and monitoring tools. The system has been developed, thoroughly tested, and brought to production to provide highly reliable, scalable, flexible and available database services for ATLAS Monte Carlo production, reconstruction and physics analysis.

A retrospective analysis of real-world use of the eaTracker® My Goals website by adults from Ontario and Alberta, Canada.

Science.gov (United States)

Lieffers, Jessica R L; Haresign, Helen; Mehling, Christine; Hanning, Rhona M

2016-09-15

Little is known about use of goal setting and tracking tools within online programs to support nutrition and physical activity behaviour change. In 2011, Dietitians of Canada added "My Goals," a nutrition and physical activity behaviour goal setting and tracking tool to their free publicly available self-monitoring website (eaTracker® ( http://www.eaTracker.ca/ )). My Goals allows users to: a) set "ready-made" SMART (Specific, Measurable, Attainable, Realistic, Time-related) goals (choice of n = 87 goals from n = 13 categories) or "write your own" goals, and b) track progress using the "My Goals Tracker." The purpose of this study was to characterize: a) My Goals user demographics, b) types of goals set, and c) My Goals Tracker use. Anonymous data on all goals set using the My Goals feature from December 6/2012-April 28/2014 by users ≥19y from Ontario and Alberta, Canada were obtained. This dataset contained: anonymous self-reported user demographic data, user set goals, and My Goals Tracker use data. Write your own goals were categorized by topic and specificity. Data were summarized using descriptive statistics. Multivariate binary logistic regression was used to determine associations between user demographics and a) goal topic areas and b) My Goals Tracker use. Overall, n = 16,511 goal statements (75.4 % ready-made; 24.6 % write your own) set by n = 8,067 adult users 19-85y (83.3 % female; mean age 41.1 ± 15.0y, mean BMI 28.8 ± 7.6kg/m(2)) were included for analysis. Overall, 33.1 % of ready-made goals were from the "Managing your Weight" category. Of write your own goal entries, 42.3 % were solely distal goals (most related to weight management); 38.6 % addressed nutrition behaviour change (16.6 % had unspecific general eating goals); 18.1 % addressed physical activity behaviour change (47.3 % had goals without information on exercise amount and type). Many write your own goals were poor quality (e.g., non-specific (e.g., missing

Temporal Role for MyD88 in a Model of Brucella-Induced Arthritis and Musculoskeletal Inflammation.

Science.gov (United States)

Lacey, Carolyn A; Mitchell, William J; Brown, Charles R; Skyberg, Jerod A

2017-03-01

Brucella spp. are facultative intracellular Gram-negative bacteria that cause the zoonotic disease brucellosis, one of the most common global zoonoses. Osteomyelitis, arthritis, and musculoskeletal inflammation are common focal complications of brucellosis in humans; however, wild-type (WT) mice infected systemically with conventional doses of Brucella do not develop these complications. Here we report C57BL/6 WT mice infected via the footpad with 10 3 to 10 6 CFU of Brucella spp. display neutrophil and monocyte infiltration of the joint space and surrounding musculoskeletal tissue. Joint inflammation is detectable as early as 1 day postinfection and peaks 1 to 2 weeks later, after which WT mice are able to slowly resolve inflammation. B and T cells were dispensable for the onset of swelling but required for resolution of joint inflammation and infection. At early time points, MyD88 -/- mice display decreased joint inflammation, swelling, and proinflammatory cytokine levels relative to WT mice. Subsequently, swelling of MyD88 -/- joints surpassed WT joint swelling, and resolution of joint inflammation was prolonged. Joint bacterial loads in MyD88 -/- mice were significantly greater than those in WT mice by day 3 postinfection and at all time points thereafter. In addition, MyD88 -/- joint inflammatory cytokine levels on day 3 and beyond were similar to WT levels. Collectively these data demonstrate MyD88 signaling mediates early inflammatory responses in the joint but also contributes to subsequent clearance of Brucella and resolution of inflammation. This work also establishes a mouse model for studying Brucella -induced arthritis, musculoskeletal complications, and systemic responses, which will lead to a better understanding of focal complications of brucellosis. Copyright © 2017 American Society for Microbiology.

41 CFR 304-3.16 - What must I submit to my agency for reimbursement when a non-Federal source pays all or part of...

Science.gov (United States)

2010-07-01

... agency for reimbursement when a non-Federal source pays all or part of my travel expenses to attend a meeting? 304-3.16 Section 304-3.16 Public Contracts and Property Management Federal Travel Regulation... submit to my agency for reimbursement when a non-Federal source pays all or part of my travel expenses to...

13 CFR 114.109 - What if my claim is denied?

Science.gov (United States)

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What if my claim is denied? 114.109 Section 114.109 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION ADMINISTRATIVE CLAIMS... representative in writing by certified or registered mail if it denies your claim. You have a right to file suit...

41 CFR 102-117.345 - Is there a requirement for me to report to GSA on my transportation activities?

Science.gov (United States)

2010-07-01

... for me to report to GSA on my transportation activities? 102-117.345 Section 102-117.345 Public... requirement for me to report to GSA on my transportation activities? (a) Currently, there is no requirement for reporting to GSA on your transportation activities. However, GSA will work with your agency and...

Lactobacillus rhamnosus GR-1 Limits Escherichia coli-Induced Inflammatory Responses via Attenuating MyD88-Dependent and MyD88-Independent Pathway Activation in Bovine Endometrial Epithelial Cells.

Science.gov (United States)

Liu, Mingchao; Wu, Qiong; Wang, Mengling; Fu, Yunhe; Wang, Jiufeng

2016-08-01

Intrauterine Escherichia coli infection after calving reduces fertility and causes major economic losses in the dairy industry. We investigated the protective effect of the probiotic Lactobacillus rhamnosus GR-1 on E. coli-induced cell damage and inflammation in primary bovine endometrial epithelial cells (BEECs). L. rhamnosus GR-1 reduced ultrastructure alterations and the percentage of BEECs apoptosis after E. coli challenge. Increased messenger RNA (mRNA) expression of immune response indicators, including pattern recognition receptors (toll-like receptor [TLR]2, TLR4, nucleotide-binding oligomerization domain [NOD]1, and NOD2), inflammasome proteins (NOD-like receptor family member pyrin domain-containing protein 3, apoptosis-associated speck-like protein, and caspase-1), TLR4 downstream adaptor molecules (myeloid differentiation antigen 88 [MyD88], toll-like receptor adaptor molecule 2 [TICAM2]), nuclear transcription factor kB (NF-kB), and the inflammatory cytokines tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6, IL-8, IL-10, IL-18, and interferon (IFN)-β, was observed following E. coli challenge. However, these increases were attenuated by L. rhamnosus GR-1 pretreatment. Our data indicate that L. rhamnosus GR-1 ameliorates the E. coli-induced disruption of cellular ultrastructure, subsequently reducing the percentage of BEECs apoptosis and limiting inflammatory responses, partly via attenuation of MyD88-dependent and MyD88-independent pathway activation. Certain probiotics could potentially prevent postpartum uterine diseases in dairy cows, ultimately reducing the use of antibiotics.